ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A01 compound treatment 1086541.0 -589000.0 -1.0 1373603.0 -375000.0 -0.61 -1.1394 -0.973 3629831 CBKinase1_019761 OC(=O)CC(N1CCCCC1)C(=O)Nc2ccc(Cl)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A02 compound treatment 1170668.0 -505000.0 -0.85 1606066.0 -143000.0 -0.23 -0.7693 -0.8686 3629832 CBKinase1_019762 FC(F)(F)c1ccccc1NC(=O)COc2ccc(cc2)C(=O)Nc3ccc(Cl)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A03 compound treatment 1624421.0 -50900.0 -0.09 1172161.0 -576000.0 -0.94 -0.729 -0.7684 3629833 CBKinase1_019763 CC(C)c1ccccc1Oc2coc3cc(OCC(=O)Nc4ccccc4F)ccc3c2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A04 compound treatment 1467590.0 -208000.0 -0.35 1278563.0 -470000.0 -0.77 -0.7934 -0.9369 3629834 CBKinase1_019764 COc1ccc(cc1)N2C(=O)CC(SCC(=O)Nc3ccc(C)cc3)C2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A05 compound treatment 1549356.0 -126000.0 -0.21 1442344.0 -306000.0 -0.5 -0.5058 -0.9273 3027312 CBKinase1_019765 COc1ccc(OCC(=O)c2c(O)c3ccccc3oc2=O)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A06 compound treatment 1512647.0 -163000.0 -0.28 1303315.0 -445000.0 -0.73 -0.7108 -0.9112 3629835 CBKinase1_019766 Fc1ccc2onc(C3CCN(CC3)C(=O)CSc4ncnc5sc6CCCCc6c45)c2c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A07 compound treatment 1501333.0 -174000.0 -0.29 1097475.0 -651000.0 -1.07 -0.9629 -0.8698 3629836 CBKinase1_019767 OC(=O)c1cccc(NC(=O)CSc2nnc(o2)c3ccc(Br)cc3)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A08 compound treatment 1838887.0 164000.0 0.28 1240881.0 -508000.0 -0.83 -0.3927 -0.4478 3629837 CBKinase1_019768 COc1cccc(NC(=O)CSc2ncnc3scc(c4ccc(C)cc4)c23)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A09 compound treatment 1345765.0 -330000.0 -0.56 1165939.0 -583000.0 -0.95 -1.0698 -0.9672 3629838 CBKinase1_019769 Cn1c(SCC(=O)Nc2ccccc2C(F)(F)F)nnc1c3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A10 compound treatment 1528083.0 -147000.0 -0.25 1108125.0 -641000.0 -1.05 -0.9185 -0.8514 3629839 CBKinase1_019770 CN(CCO)S(=O)(=O)c1cc(ccc1C)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A11 compound treatment 1540990.0 -134000.0 -0.23 1440520.0 -308000.0 -0.5 -0.5179 -0.9351 3629840 CBKinase1_019771 OC(=O)CSc1nc2ccccc2n1CC(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A12 compound treatment 1389357.0 -286000.0 -0.48 1244076.0 -505000.0 -0.83 -0.927 -0.9675 3629841 CBKinase1_019772 CCc1ccc(CCC(=O)Nc2ccc(Cl)cc2Cl)o1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A13 mock treatment 1363710.0 -312000.0 -0.53 1117930.0 -631000.0 -1.03 -1.1039 -0.9513 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A14 mock treatment 1535626.0 -140000.0 -0.24 1617561.0 -131000.0 -0.21 -0.3191 -0.9988 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A15 compound treatment 1352007.0 -323000.0 -0.55 1309954.0 -439000.0 -0.72 -0.8954 -0.9909 3629842 CBKinase1_019773 COC(=O)c1c(C)c(sc1NC(=S)Nc2ccc(cc2)S(=O)(=O)NC3(CC4CC5CC(C4)C3)C5)C(=O)N(C)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A16 compound treatment 1268785.0 -407000.0 -0.69 1161048.0 -588000.0 -0.96 -1.1676 -0.9864 2069132 CBKinase1_019774 Cn1c(SCc2nc3ccccc3s2)nnc1c4ccncc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A17 compound treatment 1482075.0 -193000.0 -0.33 1021302.0 -727000.0 -1.19 -1.0742 -0.869 3629843 CBKinase1_019775 O=C(Nc1ccccc1C(=O)N2CCOCC2)C3COc4ccccc4O3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A18 compound treatment 1362020.0 -313000.0 -0.53 1064655.0 -684000.0 -1.12 -1.1677 -0.9416 3629844 CBKinase1_019776 COC(=O)c1cc(OC)c(OC)cc1NC(=O)CN2CCCCC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A19 compound treatment 1598117.0 -77200.0 -0.13 1307064.0 -442000.0 -0.72 -0.6042 -0.8216 1984253 CBKinase1_019777 Cc1oc(cc1C(=O)NCC(=O)O)c2ccc3OCCOc3c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A20 compound treatment 1376022.0 -299000.0 -0.51 1195812.0 -553000.0 -0.91 -0.9989 -0.9623 3629845 CBKinase1_019778 COC(=O)c1c(NC(=O)CSc2nc[nH]n2)sc3CCCCc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A21 compound treatment 1221123.0 -454000.0 -0.77 1374573.0 -374000.0 -0.61 -0.9772 -0.9937 1803427 CBKinase1_019779 CC(Sc1nc2ccccc2[nH]1)C(=O)Nc3cccc(Cl)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A22 compound treatment 1237889.0 -437000.0 -0.74 1223754.0 -525000.0 -0.86 -1.1319 -0.9972 3629846 CBKinase1_019780 CCOC(=O)c1c(NC(=O)CSc2nc[nH]n2)sc3CCCc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A23 compound treatment 1065086.0 -610000.0 -1.03 1056930.0 -692000.0 -1.13 -1.532 -0.9989 3629847 CBKinase1_019781 COc1ccc(cc1)c2nnn(CC(=O)Nc3ccc(OC)cc3OC)n2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 A24 compound treatment 893260.0 -782000.0 -1.32 905003.0 -844000.0 -1.38 -1.9138 -0.9998 3629848 CBKinase1_019782 CC(C)CC(NS(=O)(=O)c1ccc(cc1)C(C)(C)C)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B01 compound treatment 1182629.0 -493000.0 -0.83 1418232.0 -330000.0 -0.54 -0.9726 -0.9781 3629849 CBKinase1_019783 CCOC(=O)c1c(NC(=O)CSc2nc[nH]n2)sc3CCCCCc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B02 compound treatment 1405169.0 -270000.0 -0.46 1739286.0 -9340.0 -0.02 -0.3342 -0.7304 3629850 CBKinase1_019784 Cn1c(SCc2nnn[nH]2)nc3n(C)c(=O)n(Cc4ccccc4Cl)c(=O)c13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B03 compound treatment 1556868.0 -118000.0 -0.2 1722512.0 -26100.0 -0.04 -0.1721 -0.8391 3629851 CBKinase1_019785 COc1cc(OC)c(NC(=O)CSc2nnc(c3ccncc3)n2C)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B04 compound treatment 1546532.0 -129000.0 -0.22 1663384.0 -85200.0 -0.14 -0.253 -0.9768 3629852 CBKinase1_019786 CCOc1ccc(NC(=O)C2CC(=O)n3c(N2)nc4ccccc34)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B05 compound treatment 1889817.0 214000.0 0.36 1657697.0 -90900.0 -0.15 0.1513 0.3856 3629853 CBKinase1_019787 COc1cc2CCN(Cc2cc1OC)C(=O)CSc3ncnc4sc5CC(C)CCc5c34 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B06 compound treatment 1755765.0 80400.0 0.14 1756763.0 8130.0 0.01 0.1057 0.7727 3629854 CBKinase1_019788 Nc1nc(SCC(=O)c2ccc(Oc3ccccc3)cc2)n[nH]1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B07 compound treatment 1687876.0 12500.0 0.02 1847474.0 98800.0 0.16 0.1295 0.7928 3629855 CBKinase1_019789 Fc1ccccc1NC(=O)CNS(=O)(=O)c2cccc(c2)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B08 compound treatment 1785087.0 110000.0 0.19 1793124.0 44500.0 0.07 0.1829 0.9166 3629856 CBKinase1_019790 CC(C)(C)c1ccc(cc1)S(=O)(=O)NCC(=O)Nc2ccc(F)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B09 compound treatment 1801895.0 127000.0 0.21 1700920.0 -47700.0 -0.08 0.0962 0.4217 3629857 CBKinase1_019791 COc1ccc(OC)c(NC(=O)Cn2cnc3sc(C)c(c4ccc(Cl)cc4)c3c2=O)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B10 compound treatment 1875866.0 201000.0 0.34 2009496.0 261000.0 0.43 0.5423 0.9935 3629858 CBKinase1_019792 O=C1NC(=S)N(C1Cc2ccccc2)S(=O)(=O)c3cccc4cccnc34 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B11 compound treatment 2075374.0 400000.0 0.68 1482144.0 -266000.0 -0.44 0.17 0.2109 3629859 CBKinase1_019793 COc1ccc(cc1OC)c2cn(nc2N)S(=O)(=O)c3ccccc3OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B12 compound treatment 1800724.0 125000.0 0.21 1844888.0 96300.0 0.16 0.2616 0.9893 3629860 CBKinase1_019794 COc1nc(Oc2ccc(O)nn2)nc(n1)N3CCOCC3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B13 mock treatment 2092647.0 417000.0 0.71 1737905.0 -10700.0 -0.02 0.487 0.6893 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B14 mock treatment 2086838.0 411000.0 0.7 1771451.0 22800.0 0.04 0.519 0.744 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B15 compound treatment 2186220.0 511000.0 0.86 1934638.0 186000.0 0.3 0.827 0.902 3629861 CBKinase1_019795 COC(=O)c1cc(OC)c(OC)cc1NC(=O)COc2ccccc2F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B16 compound treatment 1818567.0 143000.0 0.24 1962989.0 214000.0 0.35 0.4198 0.9836 3629862 CBKinase1_019796 OC(=O)c1cccc(c1)S(=O)(=O)NCc2ccco2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B17 compound treatment 1724363.0 49000.0 0.08 2137451.0 389000.0 0.64 0.5092 0.7925 3629863 CBKinase1_019797 FC(F)(F)c1cccc(NC(=O)CCc2nc3ccccc3[nH]2)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B18 compound treatment 1877711.0 202000.0 0.34 1745021.0 -3610.0 -0.01 0.238 0.6948 3629864 CBKinase1_019798 CCOC(=O)C1CCN(CC1)C(=O)Nc2ccc3snnc3c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B19 compound treatment 1703782.0 28400.0 0.05 2314051.0 565000.0 0.93 0.6893 0.7428 3629865 CBKinase1_019799 COc1ccc(NC(=O)c2ccc(OC(=O)CCN3C(=O)c4ccccc4C3=O)cc2)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B20 compound treatment 1740570.0 65200.0 0.11 2152950.0 404000.0 0.66 0.5466 0.8137 3120104 CBKinase1_019800 OC(=O)Cn1cc(C(=O)C2CC2)c3ccccc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B21 compound treatment 1423865.0 -251000.0 -0.43 1998491.0 250000.0 0.41 -0.0115 -0.0194 3629866 CBKinase1_019801 CCc1ccc(CCC(=O)Nc2ccc(C)c(C)c2)o1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B22 compound treatment 1722341.0 47000.0 0.08 1758446.0 9820.0 0.02 0.0676 0.8333 1350198 CBKinase1_019802 OC(=O)Cn1nnnc1c2ccc(F)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B23 compound treatment 1509567.0 -166000.0 -0.28 1468608.0 -280000.0 -0.46 -0.523 -0.9722 3120101 CBKinase1_019803 O=C(Cn1c(=O)n2ncnc2c3c4CCCCc4sc13)c5ccccc5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 B24 compound treatment 1116667.0 -559000.0 -0.95 1396649.0 -352000.0 -0.58 -1.0766 -0.9719 3629867 CBKinase1_019804 CCOc1ccccc1Nc2nc(N)nc(CSc3nncn3C)n2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C01 compound treatment 1921488.0 246000.0 0.42 1286873.0 -462000.0 -0.76 -0.2405 -0.2784 3629868 CBKinase1_019805 OC(=O)c1cccc(c1)S(=O)(=O)Nc2ccc(O)cc2Sc3nc4ccccc4s3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C02 compound treatment 1810457.0 135000.0 0.23 1522413.0 -226000.0 -0.37 -0.1005 -0.2306 3629869 CBKinase1_019806 Cc1ccc(cc1)c2csc3nnc(SCC(=O)c4ccc(Cl)c(Cl)c4)n23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C03 compound treatment 1836409.0 161000.0 0.27 1560764.0 -188000.0 -0.31 -0.0249 -0.0607 3629870 CBKinase1_019807 COc1ccc(NC(=O)c2ccco2)cc1NC(=O)c3cc(OC)c(OC)c(OC)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C04 compound treatment 2026569.0 351000.0 0.59 1950372.0 202000.0 0.33 0.6542 0.9616 3629871 CBKinase1_019808 COc1ccccc1NC(=O)Cn2cnc3sc4CC(C)CCc4c3c2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C05 compound treatment 2172762.0 497000.0 0.84 1955535.0 207000.0 0.34 0.8351 0.9201 3629872 CBKinase1_019809 NC(=O)CSc1nnc(c2ccc(Br)cc2)n1CC=C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C06 compound treatment 1927930.0 253000.0 0.43 1964607.0 216000.0 0.35 0.5526 0.9956 3629873 CBKinase1_019810 CCn1c(SCC(=O)Nc2ccc(Br)c(Cl)c2)nnc1c3ccc(Cl)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C07 compound treatment 2035226.0 360000.0 0.61 2016194.0 268000.0 0.44 0.7408 0.987 3629874 CBKinase1_019811 CCc1ccc(CCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)o1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C08 compound treatment 2340341.0 665000.0 1.13 1915719.0 167000.0 0.27 0.9896 0.8542 3629875 CBKinase1_019812 Cc1cccc(c1)c2nnc(SCC(=O)Nc3cc(ccc3C)[N+](=O)[O-])o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C09 compound treatment 1899190.0 224000.0 0.38 1960101.0 211000.0 0.35 0.513 0.999 3629876 CBKinase1_019813 COc1cc2c(cc1NC(=S)NCc3ccco3)oc4ccccc42 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C10 compound treatment 1994212.0 319000.0 0.54 1907912.0 159000.0 0.26 0.5662 0.9444 3629877 CBKinase1_019814 COC(=O)C1=C(C)NC(=O)NC1c2ccccc2OCC(=O)Nc3ccc(C)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C11 mock treatment 2166142.0 491000.0 0.83 1849786.0 101000.0 0.17 0.7047 0.8318 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C12 mock treatment 2142361.0 467000.0 0.79 1852466.0 104000.0 0.17 0.6793 0.8401 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C13 compound treatment 2044022.0 369000.0 0.62 2109165.0 361000.0 0.59 0.8591 0.9996 3629878 CBKinase1_019815 COc1ccc(NC(=O)CN2CCN(CC2)S(=O)(=O)c3ccc(Cl)cc3)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C14 compound treatment 1942114.0 267000.0 0.45 1798830.0 50200.0 0.08 0.3775 0.8224 3629879 CBKinase1_019816 CCc1ccccc1NC(=O)CSc2nnc(C)s2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C15 mock treatment 2262899.0 588000.0 0.99 1458486.0 -290000.0 -0.48 0.367 0.3329 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C16 mock treatment 2230675.0 555000.0 0.94 1561952.0 -187000.0 -0.31 0.4483 0.4535 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C17 compound treatment 2051872.0 377000.0 0.64 2087430.0 339000.0 0.56 0.8433 0.9976 3629880 CBKinase1_019817 COC(=O)c1ccc(NC(=O)CN(c2ccc(I)cc2)S(=O)(=O)C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C18 compound treatment 1996759.0 321000.0 0.54 1817072.0 68400.0 0.11 0.464 0.8353 3629881 CBKinase1_019818 Nc1ncnc(NCCN2CCOCC2)c1[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C19 compound treatment 1908719.0 233000.0 0.4 1915094.0 166000.0 0.27 0.4722 0.9837 3629882 CBKinase1_019819 COCCNC(=S)N1CCN(Cc2ccco2)CC1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C20 compound treatment 2094011.0 419000.0 0.71 2001704.0 253000.0 0.41 0.7944 0.9674 3629883 CBKinase1_019820 Cc1cc(C)nc(NS(=O)(=O)c2ccc(Nc3nc(cs3)c4ccc(O)cc4)cc2)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C21 compound treatment 2251556.0 576000.0 0.98 1564520.0 -184000.0 -0.3 0.4763 0.4665 3629884 CBKinase1_019821 CS(=O)(=O)N(CC(=O)Nc1ccc(Br)cc1F)c2cccc(c2)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C22 compound treatment 1679868.0 4510.0 0.01 1355711.0 -393000.0 -0.64 -0.4499 -0.6987 3629885 CBKinase1_019822 COc1ccc2nc(Nc3nc(C)c(CCC(C)C)c(=O)[nH]3)nc(C)c2c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C23 compound treatment 1862348.0 187000.0 0.32 1343177.0 -405000.0 -0.66 -0.2461 -0.3343 1304731 CBKinase1_019823 O=C(Cn1cnc2scc(c3ccccc3)c2c1=O)Nc4ccc(Oc5ccccc5)cc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 C24 compound treatment 1472105.0 -203000.0 -0.34 1306399.0 -442000.0 -0.72 -0.7558 -0.942 3629886 CBKinase1_019824 CC(C)C(NS(=O)(=O)c1ccc(F)c(Cl)c1)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D01 compound treatment 1249611.0 -426000.0 -0.72 1513921.0 -235000.0 -0.38 -0.7816 -0.9568 3629887 CBKinase1_019825 COc1ccc(NC(=O)c2ccc(OCC(=O)Nc3ccccc3F)cc2)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D02 compound treatment 1764432.0 89100.0 0.15 1928732.0 180000.0 0.3 0.3153 0.9514 3629888 CBKinase1_019826 Brc1ccccc1NC(=O)CSc2ncn(n2)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D03 compound treatment 1739909.0 64500.0 0.11 1980380.0 232000.0 0.38 0.3458 0.875 3629889 CBKinase1_019827 Cc1ccc(cc1)c2csc3ncnc(SCC(=O)Nc4ccc(cc4)S(=O)(=O)N)c23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D04 compound treatment 2011949.0 337000.0 0.57 2111813.0 363000.0 0.6 0.8238 0.9998 3629890 CBKinase1_019828 COC(=O)c1ccccc1NC(=O)C2=C(C)NC(=S)NC2c3cc(Cl)cc(OC)c3OC(C)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D05 compound treatment 1796685.0 121000.0 0.21 1872729.0 124000.0 0.2 0.289 1.0 3629891 CBKinase1_019829 CN1CCN(CC(=O)Nc2ccc(Br)cc2C(=O)c3ccccc3)CC1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D06 compound treatment 2161216.0 486000.0 0.82 2234691.0 486000.0 0.8 1.1448 0.9999 3629892 CBKinase1_019830 CC(Sc1nc(N)c2c3CCC(C)Cc3sc2n1)C(=O)Nc4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D07 compound treatment 2692895.0 1020000.0 1.72 2547776.0 799000.0 1.31 2.144 0.9909 3629893 CBKinase1_019831 Nc1c(C(=O)NCc2ccccc2)c3nc4ccccc4nc3n1CCO 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D08 compound treatment 2175611.0 500000.0 0.85 2287348.0 539000.0 0.88 1.2231 0.9998 3629894 CBKinase1_019832 Cc1cc(C)cc(c1)N2C(=O)CC(SCC(=O)Nc3ccc(Cl)cc3)C2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D09 compound treatment 2048132.0 373000.0 0.63 2278032.0 529000.0 0.87 1.0597 0.9878 3629895 CBKinase1_019833 CC(=O)c1ccc(NC(=O)CNS(=O)(=O)c2ccc(cc2)C(C)(C)C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D10 compound treatment 2147435.0 472000.0 0.8 2266314.0 518000.0 0.85 1.165 0.9996 3629896 CBKinase1_019834 Cc1cccc(c1)c2nnc(SCC(=O)Nc3c(C)cc(I)cc3C)o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D11 mock treatment 2158194.0 483000.0 0.82 2282221.0 534000.0 0.87 1.1963 0.9994 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D12 mock treatment 2109020.0 434000.0 0.73 2298925.0 550000.0 0.9 1.1568 0.9948 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D13 compound treatment 2078875.0 404000.0 0.68 2491604.0 743000.0 1.22 1.344 0.9626 1186879 CBKinase1_019835 CCOC(=O)c1c(NC(=O)c2ccccc2)scc1C3COc4ccccc4O3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D14 compound treatment 2001963.0 327000.0 0.55 2123847.0 375000.0 0.61 0.8257 0.9986 3629897 CBKinase1_019836 COC(=O)c1ccccc1NC(=O)CN2CCN(C)CC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D15 mock treatment 2124781.0 449000.0 0.76 2344522.0 596000.0 0.98 1.2285 0.9924 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D16 mock treatment 2243657.0 568000.0 0.96 2226485.0 478000.0 0.78 1.234 0.9948 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D17 compound treatment 1475523.0 -200000.0 -0.34 2001454.0 253000.0 0.41 0.0538 0.1006 3629898 CBKinase1_019837 Cn1c(SCC(=O)c2ccc(F)cc2)nnc1c3ccc(NC(=O)c4ccccc4Br)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D18 compound treatment 1867114.0 192000.0 0.32 2242397.0 494000.0 0.81 0.8017 0.9195 3629899 CBKinase1_019838 Cc1nc(CSc2ncnc3scc(c4ccc(C)cc4)c23)cs1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D19 compound treatment 2052193.0 377000.0 0.64 1938475.0 190000.0 0.31 0.671 0.9455 3629900 CBKinase1_019839 OC(c1nc2ccccc2n1CCOc3ccccc3)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D20 compound treatment 1832138.0 157000.0 0.27 2117341.0 369000.0 0.6 0.6149 0.9318 3629901 CBKinase1_019840 Cn1c(CN2CCOCC2)nnc1SCC(=O)Nc3ccccc3Br 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D21 compound treatment 1922613.0 247000.0 0.42 1874174.0 126000.0 0.21 0.4414 0.9465 3629902 CBKinase1_019841 Cc1ccc(cc1)n2c(CNCc3cccnc3)nc4ccccc4c2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D22 compound treatment 1856303.0 181000.0 0.31 1665983.0 -82600.0 -0.14 0.1208 0.3607 3629903 CBKinase1_019842 Cc1oc(cc1C(=O)NCc2ccco2)c3cc(Cl)cc(Cl)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D23 compound treatment 1771813.0 96500.0 0.16 1824968.0 76300.0 0.13 0.2039 0.9914 3629904 CBKinase1_019843 Oc1ccnc(SCC(=O)N2CCN(CC2)c3ccccc3)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 D24 compound treatment 1513581.0 -162000.0 -0.27 1428165.0 -320000.0 -0.53 -0.565 -0.9539 3629905 CBKinase1_019844 Cn1cnnc1SCc2nc3ccc(cc3[nH]2)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E01 mock treatment 1192094.0 -483000.0 -0.82 1460196.0 -288000.0 -0.47 -0.9127 -0.966 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E02 mock treatment 1422686.0 -253000.0 -0.43 1670780.0 -77900.0 -0.13 -0.3927 -0.8797 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E03 compound treatment 1700276.0 24900.0 0.04 1823715.0 75100.0 0.12 0.1168 0.8982 3629906 CBKinase1_019845 C(Sc1nnc(c2cccs2)n1c3ccccc3)c4nc5ccccc5s4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E04 compound treatment 1784767.0 109000.0 0.19 1872933.0 124000.0 0.2 0.275 0.9989 3629907 CBKinase1_019846 Cc1ccc(cc1)c2nnc(SCC(=O)Nc3ccc(Br)c(Cl)c3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E05 compound treatment 1783592.0 108000.0 0.18 2066233.0 318000.0 0.52 0.4976 0.9018 3629908 CBKinase1_019847 Nc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(c3)C(F)(F)F)n2c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E06 compound treatment 1623590.0 -51800.0 -0.09 2149979.0 401000.0 0.66 0.4031 0.6075 3629909 CBKinase1_019848 Clc1cccc(NC(=O)CC2NCCNC2=O)c1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E07 compound treatment 1752619.0 77300.0 0.13 2043162.0 295000.0 0.48 0.4338 0.8674 3629910 CBKinase1_019849 Cn1c(SCC(=O)Nc2ccccc2F)nnc1c3cc4ccccc4o3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E08 compound treatment 1849639.0 174000.0 0.3 1649716.0 -98900.0 -0.16 0.094 0.2792 3629911 CBKinase1_019850 CCn1c(SCC(=O)N2CCN(CC2)c3ccccc3)nnc1c4cc5cc(Cl)ccc5o4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E09 mock treatment 1905863.0 231000.0 0.39 2130526.0 382000.0 0.63 0.7185 0.9741 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E10 mock treatment 1764762.0 89400.0 0.15 2315563.0 567000.0 0.93 0.764 0.8116 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E11 compound treatment 1893681.0 218000.0 0.37 2050118.0 301000.0 0.49 0.6107 0.9898 3629912 CBKinase1_019851 COc1ccc(OC)c(c1)N(CC(=O)Nc2ccc(Br)cc2F)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E12 compound treatment 1761907.0 86500.0 0.15 2222478.0 474000.0 0.78 0.6527 0.8259 3629913 CBKinase1_019852 Cc1ccc(cc1S(=O)(=O)NCCCO)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E13 compound treatment 1743651.0 68300.0 0.12 1940908.0 192000.0 0.32 0.3046 0.9074 3629914 CBKinase1_019853 COc1ccc(cc1Cl)N(CC(=O)Nc2ccc(cc2)C(F)(F)F)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E14 compound treatment 1738806.0 63400.0 0.11 1965949.0 217000.0 0.36 0.3278 0.8811 1126888 CBKinase1_019854 Clc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)NCc3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E15 compound treatment 306199.0 -1370000.0 -2.32 310646.0 -1440000.0 -2.36 -3.3052 -1.0 3629915 CBKinase1_019855 Cc1ccc(C)c(NC(=O)CC2N(Cc3ccco3)C(=S)N(C2=O)c4ccccc4)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E16 compound treatment 1711040.0 35700.0 0.06 2176294.0 428000.0 0.7 0.5383 0.7652 3629916 CBKinase1_019856 Cc1ccccc1NC(=O)CSC2CC(=O)N(C2=O)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E17 mock treatment 2213758.0 538000.0 0.91 1856885.0 108000.0 0.18 0.7699 0.8292 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E18 mock treatment 1922863.0 248000.0 0.42 2031716.0 283000.0 0.46 0.6243 0.9987 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E19 compound treatment 1647260.0 -28100.0 -0.05 1992036.0 243000.0 0.4 0.2484 0.6184 1588077 CBKinase1_019857 Nc1ncnc2n(Cc3ccccc3)c4nc5ccccc5nc4c12 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E20 compound treatment 1296340.0 -379000.0 -0.64 1903937.0 155000.0 0.25 -0.2737 -0.3965 1309165 CBKinase1_019858 CCN(CC)CCNc1ncnc2sc3COC(C)(C)Cc3c12 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E21 compound treatment 1737510.0 62100.0 0.11 1708878.0 -39800.0 -0.07 0.0283 0.2289 3629917 CBKinase1_019859 OC1(CC(=O)c2ccccn2)C(=O)N(Cc3cccc4ccccc34)c5ccccc51 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E22 compound treatment 1834861.0 160000.0 0.27 1910612.0 162000.0 0.27 0.3786 1.0 1617160 CBKinase1_019860 CCOc1ccc2nc(SCC(=O)Nc3c(C)n(C)n(c4ccccc4)c3=O)sc2c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E23 compound treatment 1659804.0 -15600.0 -0.03 1661701.0 -86900.0 -0.14 -0.1194 -0.8238 3629918 CBKinase1_019861 O=C1CC(Cc2nc(NCc3ccco3)ncc12)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 E24 compound treatment 1420482.0 -255000.0 -0.43 1513051.0 -236000.0 -0.39 -0.5781 -0.9985 3629919 CBKinase1_019862 O=C(CSc1nc2ccccc2c(=O)[nH]1)Nc3ccc4OCCOc4c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F01 mock treatment 1291551.0 -384000.0 -0.65 1329575.0 -419000.0 -0.69 -0.945 -0.9996 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F02 mock treatment 1470816.0 -205000.0 -0.35 1764376.0 15700.0 0.03 -0.2266 -0.6526 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F03 compound treatment 1458592.0 -217000.0 -0.37 1823587.0 75000.0 0.12 -0.1726 -0.446 3629920 CBKinase1_019863 CC(C)OCCCNc1ncnc(N)c1[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F04 compound treatment 1575084.0 -100000.0 -0.17 1797428.0 48800.0 0.08 -0.0635 -0.3383 3629921 CBKinase1_019864 COC(=O)c1ccccc1NC(=O)CN2CCOCC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F05 compound treatment 1664517.0 -10800.0 -0.02 2108108.0 359000.0 0.59 0.4036 0.6847 3629922 CBKinase1_019865 CNC(=O)CN(C#N)c1nc(C)cc(C)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F06 compound treatment 1534155.0 -141000.0 -0.24 2226454.0 478000.0 0.78 0.3847 0.4699 3629923 CBKinase1_019866 Nc1ncnc2[nH]c(SCc3nc4ccc(I)cc4c(=O)n3c5ccccc5)nc12 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F07 compound treatment 1655037.0 -20300.0 -0.03 1999844.0 251000.0 0.41 0.2668 0.6458 3629924 CBKinase1_019867 COc1ccc(OC)c(c1)n2c(CN3CCC(CC3)C(=O)N)nc4ccccc4c2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F08 compound treatment 1713903.0 38500.0 0.07 2036340.0 288000.0 0.47 0.3795 0.7973 3629925 CBKinase1_019868 CCc1c(O)nc(SCC(=O)N)n(c2ccccc2F)c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F09 mock treatment 1880349.0 205000.0 0.35 1949019.0 200000.0 0.33 0.4776 0.9996 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F10 mock treatment 1826656.0 151000.0 0.26 2194117.0 445000.0 0.73 0.6973 0.9013 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F11 compound treatment 1788349.0 113000.0 0.19 2244645.0 496000.0 0.81 0.7101 0.8503 3629926 CBKinase1_019869 Cc1ccc(NC(=O)CSc2nncn2C)c(C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F12 compound treatment 1741311.0 66000.0 0.11 2125324.0 377000.0 0.62 0.5155 0.8216 3087333 CBKinase1_019870 Cc1cc(C)nc(NC2=NC(=O)CC(N2c3cccc(Cl)c3)C(=O)O)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F13 compound treatment 1765360.0 90000.0 0.15 2231013.0 482000.0 0.79 0.6667 0.8281 3629927 CBKinase1_019871 FC(F)(F)c1cccc(NC(=O)CC2NC(=O)NC2=O)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F14 compound treatment 1774100.0 98700.0 0.17 2053549.0 305000.0 0.5 0.4715 0.8949 3629928 CBKinase1_019872 COC(=O)C(C)N(C#N)c1nc(C)nc(C)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F15 compound treatment 1620619.0 -54700.0 -0.09 1990218.0 242000.0 0.4 0.2144 0.5274 3629929 CBKinase1_019873 Cc1nc(CSc2nc(C)nc3sc4CCCCc4c23)cs1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F16 compound treatment 1493020.0 -182000.0 -0.31 2250127.0 501000.0 0.82 0.3629 0.4134 3629930 CBKinase1_019874 O=C(CSc1nc[nH]n1)Nc2sc3CCCCCc3c2C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F17 mock treatment 1716071.0 40700.0 0.07 2222271.0 474000.0 0.78 0.5976 0.7669 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F18 mock treatment 1659752.0 -15600.0 -0.03 1958990.0 210000.0 0.34 0.2251 0.651 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F19 compound treatment 1721109.0 45700.0 0.08 2121090.0 372000.0 0.61 0.4864 0.7905 3629931 CBKinase1_019875 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2cccc(c2)c3cn4ccc(C)cc4n3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F20 compound treatment 1730313.0 55000.0 0.09 1929575.0 181000.0 0.3 0.2755 0.8863 3629932 CBKinase1_019876 COc1ccc(NC(=O)Cc2nc(cs2)c3cc4ccccc4oc3=O)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F21 compound treatment 1723885.0 48500.0 0.08 1896232.0 148000.0 0.24 0.2291 0.8969 3629933 CBKinase1_019877 COc1cc(NC(=S)NC(=O)C(C)Oc2ccc(Cl)cc2Cl)c(OC)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F22 compound treatment 1537772.0 -138000.0 -0.23 1812492.0 63900.0 0.1 -0.0907 -0.3551 3629934 CBKinase1_019878 Cc1c(Cl)cccc1NC(=O)CSc2nccc(O)n2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F23 compound treatment 1514081.0 -161000.0 -0.27 1601684.0 -147000.0 -0.24 -0.3633 -0.998 1639059 CBKinase1_019879 Oc1ccnc(SCC(=O)N2CCc3ccccc23)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 F24 compound treatment 1554148.0 -121000.0 -0.21 1157314.0 -591000.0 -0.97 -0.8303 -0.8382 3629935 CBKinase1_019880 Clc1cc(Br)ccc1NC(=O)CSc2nc3ccccc3[nH]2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G01 compound treatment 1289108.0 -386000.0 -0.65 1347595.0 -401000.0 -0.66 -0.9271 -1.0 3629936 CBKinase1_019881 CSc1ccccc1NC(=O)CN(C)S(=O)(=O)c2ccc(C)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G02 compound treatment 1524679.0 -151000.0 -0.26 1561681.0 -187000.0 -0.31 -0.397 -0.9958 3629937 CBKinase1_019882 COc1ccccc1NC(=O)CSc2nccc(O)n2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G03 mock treatment 1680125.0 4760.0 0.01 1507774.0 -241000.0 -0.39 -0.2734 -0.6925 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G04 mock treatment 1643433.0 -31900.0 -0.05 1821000.0 72400.0 0.12 0.0457 0.3503 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G05 compound treatment 1689302.0 13900.0 0.02 1681743.0 -66900.0 -0.11 -0.0608 -0.5425 3629938 CBKinase1_019883 Cc1cccc(c1)c2nnc(SCC(=O)Nc3ccccc3F)o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G06 compound treatment 1626219.0 -49100.0 -0.08 1870959.0 122000.0 0.2 0.0829 0.3821 3629939 CBKinase1_019884 CCOC(=O)c1ccc(NC(=O)CN2C(=O)CNC2=O)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G07 compound treatment 1668038.0 -7320.0 -0.01 1849963.0 101000.0 0.17 0.1087 0.6525 3629940 CBKinase1_019885 Cc1cc(Oc2coc3cc(OCC(=O)Nc4ccccc4F)ccc3c2=O)cc(C)c1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G08 compound treatment 1753937.0 78600.0 0.13 1768883.0 20300.0 0.03 0.1175 0.8573 3629941 CBKinase1_019886 CN(C(=O)CSc1nc(O)cc(=O)n1c2ccccc2F)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G09 compound treatment 1610395.0 -65000.0 -0.11 1967903.0 219000.0 0.36 0.1763 0.4692 3629942 CBKinase1_019887 [O-][N+](=O)c1ncn(CC(=O)Nc2c(Cl)cccc2Cl)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G10 compound treatment 1731306.0 55900.0 0.09 1923618.0 175000.0 0.29 0.2697 0.8932 3629943 CBKinase1_019888 Cc1cc(C)c(C)c(c1C)S(=O)(=O)NCC(=O)Nc2ccc3OCCOc3c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G11 compound treatment 1925553.0 250000.0 0.42 1848878.0 100000.0 0.16 0.4156 0.915 3629944 CBKinase1_019889 CC(=O)Nc1c(O)nc(SCC(=O)N(c2ccccc2)c3ccccc3)[nH]c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G12 compound treatment 1476410.0 -199000.0 -0.34 2163872.0 415000.0 0.68 0.2431 0.3201 3629945 CBKinase1_019890 CC1CCc2c(C1)sc3ncnc(SCC(=O)NCC4CCCO4)c23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G13 compound treatment 1703780.0 28400.0 0.05 1826046.0 77400.0 0.13 0.1237 0.9119 3629946 CBKinase1_019891 CN(c1cccc(NC(=O)c2ccc(Cl)c(c2)S(=O)(=O)N3CCOCC3)c1)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G14 compound treatment 2076742.0 401000.0 0.68 2016652.0 268000.0 0.44 0.791 0.9777 3629947 CBKinase1_019892 CC(NS(=O)(=O)c1ccc(Br)cc1)C(=O)Nc2cccc(c2)C(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G15 compound treatment 1608828.0 -66500.0 -0.11 1949719.0 201000.0 0.33 0.1534 0.4405 3629948 CBKinase1_019893 Cc1cc(C)nc(Nc2n[nH]c(n2)c3cccnc3)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G16 compound treatment 1844493.0 169000.0 0.29 1970343.0 222000.0 0.36 0.4594 0.993 3629949 CBKinase1_019894 COc1ccc(CNCC(O)c2nnn(C)n2)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G17 compound treatment 1634665.0 -40700.0 -0.07 1889729.0 141000.0 0.23 0.1148 0.4758 3629950 CBKinase1_019895 CCOC(=O)c1c(NC(=S)Nc2cc(ccc2OC)[N+](=O)[O-])sc3CCCCCc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G18 compound treatment 1692183.0 16800.0 0.03 1553722.0 -195000.0 -0.32 -0.2057 -0.6415 3629951 CBKinase1_019896 COc1ccc(CNCc2nc3ccccc3c(=O)n2c4ccc(F)cc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G19 mock treatment 1873990.0 199000.0 0.34 1906991.0 158000.0 0.26 0.4213 0.9918 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G20 mock treatment 1675587.0 227.0 0.0 1958045.0 209000.0 0.34 0.243 0.7079 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G21 compound treatment 1710202.0 34800.0 0.06 1905227.0 157000.0 0.26 0.2232 0.8475 3629952 CBKinase1_019897 COC(=O)c1c(NC(=S)Nc2nc(C)cc(C)n2)sc3CC(C)CCc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G22 compound treatment 1650647.0 -24700.0 -0.04 1725855.0 -22800.0 -0.04 -0.056 -0.9984 3629953 CBKinase1_019898 COCCNC(=S)Nc1nc(OC)cc(OC)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G23 compound treatment 1629647.0 -45700.0 -0.08 1562607.0 -186000.0 -0.3 -0.2703 -0.8593 3629954 CBKinase1_019899 CC(=O)c1ccc(NC(=O)CNS(=O)(=O)c2cccc(Cl)c2)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 G24 compound treatment 1341347.0 -334000.0 -0.57 1522091.0 -227000.0 -0.37 -0.6623 -0.9792 3629955 CBKinase1_019900 Clc1cccc(Cl)c1NC(=O)CSc2nnc(c3ccncc3)n2c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H01 compound treatment 1235087.0 -440000.0 -0.75 1351212.0 -397000.0 -0.65 -0.9875 -0.9977 3629956 CBKinase1_019901 CCOC(=O)c1c(NC(=O)C2(C)Cc3ccccc3C(=O)O2)sc4CCCCc14 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H02 compound treatment 1667021.0 -8340.0 -0.01 1740307.0 -8320.0 -0.01 -0.0196 -0.9999 3629957 CBKinase1_019902 COc1ccc(CCNc2nc(cs2)c3ccc(OC)c(OC)c3)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H03 mock treatment 1629240.0 -46100.0 -0.08 1704002.0 -44600.0 -0.07 -0.1069 -0.9995 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H04 mock treatment 1641341.0 -34000.0 -0.06 1474057.0 -275000.0 -0.45 -0.3589 -0.7911 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H05 compound treatment 1604102.0 -71300.0 -0.12 1746260.0 -2370.0 0.0 -0.088 -0.7295 3629958 CBKinase1_019903 O=C(Cn1nnc2ccccc12)NCCN3CCCC3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H06 compound treatment 1702771.0 27400.0 0.05 1660131.0 -88500.0 -0.15 -0.0698 -0.458 3629959 CBKinase1_019904 CCOC(=O)c1ccc(NC(=O)CN2c3cccc4cccc(c34)S2(=O)=O)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H07 compound treatment 1750317.0 75000.0 0.13 1839749.0 91100.0 0.15 0.1953 0.9967 1347119 CBKinase1_019905 Cn1c(=O)n(C)c2nc(SCC(=O)O)n(Cc3ccc(F)cc3)c2c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H08 compound treatment 1609591.0 -65800.0 -0.11 2047433.0 299000.0 0.49 0.2676 0.5328 3629960 CBKinase1_019906 Nc1ccc(cc1)c2nnc(SCC(=O)Nc3ccc(Br)cc3F)n2c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H09 compound treatment 1817010.0 142000.0 0.24 1978027.0 229000.0 0.38 0.4354 0.9764 3629961 CBKinase1_019907 O=C(Nc1ccccc1C(=O)N2CCOCC2)c3noc4CCCCc34 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H10 compound treatment 1802919.0 128000.0 0.22 1843249.0 94600.0 0.16 0.2623 0.9868 1429480 CBKinase1_019908 CC(C)(C)c1ccc(cc1)S(=O)(=O)NCCC(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H11 compound treatment 1813850.0 138000.0 0.23 2012199.0 264000.0 0.43 0.4712 0.9588 3629962 CBKinase1_019909 COc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(c3)C(F)(F)F)[nH]2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H12 compound treatment 1843762.0 168000.0 0.29 2071012.0 322000.0 0.53 0.5752 0.9581 3629963 CBKinase1_019910 Cc1ccc(NC(=O)CSc2nc(O)c(C)c(=O)n2c3ccccc3F)c(C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H13 compound treatment 1830562.0 155000.0 0.26 2034827.0 286000.0 0.47 0.5174 0.9625 3629964 CBKinase1_019911 CCOC(=O)c1c(NC(=O)Cc2cccc(OC)c2)sc3CCCCc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H14 compound treatment 1659579.0 -15800.0 -0.03 1979290.0 231000.0 0.38 0.2484 0.6555 3629965 CBKinase1_019912 Cc1cccc(NC(=O)c2cc(NC(=O)C3CCCCC3C(=O)O)ccc2N4CCOCC4)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H15 compound treatment 1619676.0 -55700.0 -0.09 1949872.0 201000.0 0.33 0.1666 0.4856 3629966 CBKinase1_019913 Clc1ccccc1OCCSc2nnc(c3cccnc3)n2c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H16 compound treatment 1655848.0 -19500.0 -0.03 1846909.0 98300.0 0.16 0.0905 0.5506 3629967 CBKinase1_019914 Cn1c(SCC(=O)Nc2ccc(cc2)C(=O)O)nnc1c3ccc(Br)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H17 compound treatment 1655165.0 -20200.0 -0.03 1828936.0 80300.0 0.13 0.0689 0.5066 3629968 CBKinase1_019915 CSc1ccccc1NC(=O)CN(C)S(=O)(=O)c2ccc(Br)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H18 compound treatment 1624708.0 -50700.0 -0.09 1553775.0 -195000.0 -0.32 -0.2864 -0.8663 3629969 CBKinase1_019916 [O-][N+](=O)c1ccc(NC(=O)NCCCN2CCCC2=O)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H19 mock treatment 1547187.0 -128000.0 -0.22 1716374.0 -32300.0 -0.05 -0.1908 -0.8544 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H20 mock treatment 1495657.0 -180000.0 -0.3 1881158.0 133000.0 0.22 -0.0615 -0.1646 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H21 compound treatment 1579836.0 -95500.0 -0.16 1887922.0 139000.0 0.23 0.0471 0.1683 3629970 CBKinase1_019917 Fc1ccc(NC(=O)CCc2nc3ccccc3[nH]2)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H22 compound treatment 1580261.0 -95100.0 -0.16 1610309.0 -138000.0 -0.23 -0.2741 -0.9859 3629971 CBKinase1_019918 COc1ccc(NC(=O)c2c(NC(=O)Cc3ccc(OC)c(OC)c3)sc4CCCc24)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H23 compound treatment 1594031.0 -81300.0 -0.14 1576826.0 -172000.0 -0.28 -0.2964 -0.9458 3629972 CBKinase1_019919 CCn1c(SCC(=O)Nc2ccc(cc2C)[N+](=O)[O-])nnc1c3ccc(Br)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 H24 compound treatment 1418073.0 -257000.0 -0.44 1472698.0 -276000.0 -0.45 -0.6277 -0.9998 3629973 CBKinase1_019920 Oc1cccc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I01 compound treatment 1462936.0 -212000.0 -0.36 1431293.0 -317000.0 -0.52 -0.622 -0.9838 3629974 CBKinase1_019921 Cc1c(CC(=O)O)c(=O)oc2c(C)c(OCC(=O)O)ccc12 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I02 compound treatment 1415119.0 -260000.0 -0.44 1639419.0 -109000.0 -0.18 -0.4381 -0.9213 3629975 CBKinase1_019922 Cn1c(SCC(=O)N2CCN(Cc3ccccc3)CC2)nnc1c4ccncc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I03 compound treatment 1574300.0 -101000.0 -0.17 1591713.0 -157000.0 -0.26 -0.3028 -0.9804 3629976 CBKinase1_019923 CCC1(C)Cc2c(CO1)sc3nnn(CC(=O)Nc4ccc(OC)cc4OC)c(=O)c23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I04 compound treatment 1647580.0 -27800.0 -0.05 1549104.0 -200000.0 -0.33 -0.2645 -0.8006 3629977 CBKinase1_019924 CC(C)C(NS(=O)(=O)c1ccccc1F)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I05 mock treatment 1529278.0 -146000.0 -0.25 1774176.0 25500.0 0.04 -0.1452 -0.5791 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I06 mock treatment 1619796.0 -55600.0 -0.09 1907141.0 159000.0 0.26 0.1172 0.4242 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I07 compound treatment 1455560.0 -220000.0 -0.37 1732998.0 -15600.0 -0.03 -0.2812 -0.754 3629978 CBKinase1_019925 COc1cc(OC)c(NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I08 compound treatment 1433380.0 -242000.0 -0.41 1685593.0 -63000.0 -0.1 -0.3627 -0.8586 3629979 CBKinase1_019926 O=C(CC1NC(=O)NC1=O)Nc2cccc3ccccc23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I09 compound treatment 1600652.0 -74700.0 -0.13 2441543.0 693000.0 1.14 0.7136 0.6245 3629980 CBKinase1_019927 OC(=O)CC(N1CCCC1)C(=O)Nc2ccc(Cl)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I10 compound treatment 1554697.0 -121000.0 -0.2 1863004.0 114000.0 0.19 -0.0119 -0.0429 3629981 CBKinase1_019928 Cc1ccc(cc1C)c2csc3ncn(CC(=O)Nc4ccc(F)c(Cl)c4)c(=O)c23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I11 compound treatment 1649437.0 -25900.0 -0.04 1809055.0 60400.0 0.1 0.039 0.36 3629982 CBKinase1_019929 CCn1nc(C)c(NC(=S)NCc2ccco2)c1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I12 compound treatment 1753299.0 77900.0 0.13 1738293.0 -10300.0 -0.02 0.0813 0.6113 3629983 CBKinase1_019930 COc1ccc(CN2C(=O)C(O)(CC(=O)c3cccs3)c4ccccc24)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I13 compound treatment 1701021.0 25700.0 0.04 1909520.0 161000.0 0.26 0.2172 0.8126 3629984 CBKinase1_019931 Clc1ccccc1NC(=O)CC2NCCNC2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I14 compound treatment 1439720.0 -236000.0 -0.4 1819948.0 71300.0 0.12 -0.1994 -0.4797 3629985 CBKinase1_019932 COc1ccc(CN2C(=O)C(O)(CC(=O)c3cccnc3)c4ccccc24)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I15 compound treatment 1605453.0 -69900.0 -0.12 1897458.0 149000.0 0.24 0.0888 0.3275 3629986 CBKinase1_019933 COc1ccc(OC)c(NC(=O)CSc2nncc3ccccc23)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I16 compound treatment 1629669.0 -45700.0 -0.08 1712241.0 -36400.0 -0.06 -0.0969 -0.9918 3117830 CBKinase1_019934 Cc1nn(c(O)c1C2OC(=O)c3ccccc23)c4nc5ccccc5s4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I17 compound treatment 1433535.0 -242000.0 -0.41 1573782.0 -175000.0 -0.29 -0.4921 -0.9848 3629987 CBKinase1_019935 FC(F)(F)c1ccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccccc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I18 compound treatment 1354205.0 -321000.0 -0.54 1479658.0 -269000.0 -0.44 -0.6961 -0.9946 3629988 CBKinase1_019936 COc1ccccc1n2c(SC(C)C(=O)N3CCCCC3)nc4ccc(I)cc4c2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I19 compound treatment 1630016.0 -45300.0 -0.08 1682227.0 -66400.0 -0.11 -0.1312 -0.9854 3629989 CBKinase1_019937 COc1cc(Cl)cc(C(=O)O)c1OCC(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I20 compound treatment 1634490.0 -40900.0 -0.07 1604966.0 -144000.0 -0.24 -0.2154 -0.8778 3629990 CBKinase1_019938 Cc1cc(NS(=O)(=O)c2ccc(Nc3nc(cs3)c4ccc(O)cc4)cc2)no1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I21 mock treatment 1582782.0 -92600.0 -0.16 1791826.0 43200.0 0.07 -0.0608 -0.3533 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I22 mock treatment 1664241.0 -11100.0 -0.02 1762201.0 13600.0 0.02 0.0024 0.083 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I23 compound treatment 1659735.0 -15600.0 -0.03 1652416.0 -96200.0 -0.16 -0.1302 -0.8143 3629991 CBKinase1_019939 COc1cc(CNC2CCCC2)ccc1OCC(=O)N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 I24 compound treatment 1331358.0 -344000.0 -0.58 1448401.0 -300000.0 -0.49 -0.7597 -0.9965 3629992 CBKinase1_019940 Cc1ccc(NC(=O)C2CC(=O)n3cnnc3N2)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J01 compound treatment 1065942.0 -609000.0 -1.03 1147245.0 -601000.0 -0.99 -1.4264 -0.9997 3629993 CBKinase1_019941 COc1ccccc1NC(=O)Cn2cnc3scc(c4cccc(c4)[N+](=O)[O-])c3c2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J02 compound treatment 1388575.0 -287000.0 -0.49 1313926.0 -435000.0 -0.71 -0.847 -0.9825 3629994 CBKinase1_019942 Cc1c(sc2nc(SCC(=O)Nc3ccccc3C(F)(F)F)[nH]c(=O)c12)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J03 compound treatment 1180769.0 -495000.0 -0.84 1360526.0 -388000.0 -0.64 -1.0417 -0.9908 3629995 CBKinase1_019943 CC(C)OC(=O)CSc1nc(N)c(C#N)cc1C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J04 compound treatment 1475040.0 -200000.0 -0.34 1526777.0 -222000.0 -0.36 -0.4969 -0.9994 3629996 CBKinase1_019944 COc1cccc(c1)S(=O)(=O)NCC(=O)N2CCCCC2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J05 mock treatment 1485176.0 -190000.0 -0.32 1689443.0 -59200.0 -0.1 -0.2962 -0.881 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J06 mock treatment 1047325.0 -628000.0 -1.06 1561348.0 -187000.0 -0.31 -0.9687 -0.8755 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J07 compound treatment 1338711.0 -337000.0 -0.57 1643568.0 -105000.0 -0.17 -0.5247 -0.8814 1713796 CBKinase1_019945 Cc1c(NC(=O)CN2c3cccc4cccc(c34)S2(=O)=O)c(=O)n(c5ccccc5)n1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J08 compound treatment 1596387.0 -79000.0 -0.13 1507710.0 -241000.0 -0.39 -0.3737 -0.8965 3629997 CBKinase1_019946 Cc1ccc2cccc(OCc3nnc(SCC(=O)N)n3C)c2n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J09 compound treatment 1620297.0 -55100.0 -0.09 1643827.0 -105000.0 -0.17 -0.1874 -0.9588 3629998 CBKinase1_019947 Cc1ccn2cc(nc2c1)c3cccc(NS(=O)(=O)c4cccc(c4)[N+](=O)[O-])c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J10 compound treatment 1381386.0 -294000.0 -0.5 1764577.0 15900.0 0.03 -0.3334 -0.669 3629999 CBKinase1_019948 COc1cccc(c1)S(=O)(=O)NCc2ccc(cc2)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J11 compound treatment 1811029.0 136000.0 0.23 1450445.0 -298000.0 -0.49 -0.1832 -0.3392 3630000 CBKinase1_019949 COc1ccc(OC)c(NC(=S)NCCc2c[nH]cn2)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J12 compound treatment 1615948.0 -59400.0 -0.1 1695706.0 -52900.0 -0.09 -0.1324 -0.9973 3630001 CBKinase1_019950 COc1ccccc1NC(=O)c2sc3ncn(CC(=O)Nc4ccccc4C)c(=O)c3c2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J13 compound treatment 1457731.0 -218000.0 -0.37 1685387.0 -63200.0 -0.1 -0.3338 -0.8722 3630002 CBKinase1_019951 Cc1ccc2cccc(c2n1)S(=O)(=O)NC3CCS(=O)(=O)C3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J14 compound treatment 1510326.0 -165000.0 -0.28 1749446.0 815.0 0.0 -0.1966 -0.7037 3630003 CBKinase1_019952 COC(=O)c1sccc1NC(=O)Cn2nnc(n2)c3ccc(C)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J15 compound treatment 1331124.0 -344000.0 -0.58 1489907.0 -259000.0 -0.42 -0.7119 -0.9878 3630004 CBKinase1_019953 COc1ccc(cc1N(C)S(=O)(=O)c2ccccc2)S(=O)(=O)N3CCN(CC3)c4ccccn4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J16 compound treatment 1494523.0 -181000.0 -0.31 1597083.0 -152000.0 -0.25 -0.3921 -0.9946 3630005 CBKinase1_019954 COc1cc(cc(OC)c1OC)c2nnn(CC(=O)Nc3c(C)cccc3C)n2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J17 compound treatment 1463201.0 -212000.0 -0.36 1537521.0 -211000.0 -0.35 -0.4986 -0.9998 3630006 CBKinase1_019955 Cc1ccc(cc1)c2csc3nnc(SCC(=O)Nc4ccc5OCCOc5c4)n23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J18 compound treatment 1314090.0 -361000.0 -0.61 1653574.0 -95100.0 -0.16 -0.5426 -0.8598 3630007 CBKinase1_019956 Nc1nc(Cc2c[nH]c3ccccc23)nc(NC4CCCCC4)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J19 compound treatment 1438751.0 -237000.0 -0.4 1662888.0 -85700.0 -0.14 -0.3826 -0.9013 3630008 CBKinase1_019957 CCOC(=O)CSc1nc(nc2sc3CCCCc3c12)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J20 compound treatment 1347037.0 -328000.0 -0.56 1708053.0 -40600.0 -0.07 -0.44 -0.7861 3630009 CBKinase1_019958 Cc1ccc(Cl)cc1NC(=O)CC2NCCNC2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J21 mock treatment 1464463.0 -211000.0 -0.36 1728631.0 -20000.0 -0.03 -0.2756 -0.7688 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J22 mock treatment 1540870.0 -134000.0 -0.23 1608049.0 -141000.0 -0.23 -0.3239 -1.0 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J23 compound treatment 1749592.0 74200.0 0.13 1476664.0 -272000.0 -0.45 -0.2263 -0.4887 3630010 CBKinase1_019959 CCc1ccc(CCC(=O)Nc2ccc(Br)cc2)o1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 J24 compound treatment 1486237.0 -189000.0 -0.32 1478493.0 -270000.0 -0.44 -0.5394 -0.9873 3630011 CBKinase1_019960 CC1=C(C(NC(=O)N1)c2cc(Br)ccc2OCC(=O)O)C(=O)Nc3cccc(Cl)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K01 compound treatment 2116441.0 441000.0 0.75 1507767.0 -241000.0 -0.39 0.2488 0.2946 3630012 CBKinase1_019961 COC(=O)c1cc(OC)c(OC)cc1NC(=O)COc2ccccc2Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K02 compound treatment 1624692.0 -50700.0 -0.09 1584080.0 -165000.0 -0.27 -0.2513 -0.8882 3630013 CBKinase1_019962 CCc1ccc(CCC(=O)Nc2ccc3ccccc3c2)o1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K03 compound treatment 1671323.0 -4040.0 -0.01 1907906.0 159000.0 0.26 0.1797 0.6884 3630014 CBKinase1_019963 Cc1cc(C)cc(c1)N2C(=O)CC(SCC(=O)Nc3ccc(Br)cc3)C2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K04 compound treatment 1702479.0 27100.0 0.05 1654694.0 -93900.0 -0.15 -0.0764 -0.4756 3630015 CBKinase1_019964 Oc1cc(=O)n(c(SCC(=O)N2CCc3ccccc23)n1)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K05 compound treatment 1807498.0 132000.0 0.22 1927225.0 179000.0 0.29 0.3651 0.9912 3630016 CBKinase1_019965 CC(NS(=O)(=O)c1cc(C)ccc1C)C(=O)Nc2ccc(Br)cc2F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K06 compound treatment 1661799.0 -13600.0 -0.02 1944729.0 196000.0 0.32 0.211 0.6549 2076676 CBKinase1_019966 CCn1c(SCC(=O)N2CCCc3ccccc23)nnc1c4cccs4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K07 mock treatment 1647990.0 -27400.0 -0.05 1948646.0 200000.0 0.33 0.199 0.6012 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K08 mock treatment 1589722.0 -85600.0 -0.14 1927565.0 179000.0 0.29 0.1049 0.3205 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K09 compound treatment 1905777.0 230000.0 0.39 1975347.0 227000.0 0.37 0.5385 0.9997 1875625 CBKinase1_019967 CC(=O)Nc1ccc(NS(=O)(=O)c2ccc(Cl)c(c2)C(=O)O)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K10 compound treatment 1917737.0 242000.0 0.41 2033656.0 285000.0 0.47 0.6204 0.9979 3630017 CBKinase1_019968 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)N4CCCC4C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K11 compound treatment 2287287.0 612000.0 1.04 2200511.0 452000.0 0.74 1.2561 0.9865 2067361 CBKinase1_019969 CC(=O)Nc1ccc(cc1)S(=O)(=O)NCc2ccc3[nH]c4CCCCc4c3c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K12 compound treatment 1794033.0 119000.0 0.2 2065134.0 317000.0 0.52 0.5088 0.9147 3630018 CBKinase1_019970 Oc1cc(OCC(=O)c2cccc(c2)[N+](=O)[O-])cc3oc(cc(=O)c13)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K13 compound treatment 1703798.0 28400.0 0.05 2121412.0 373000.0 0.61 0.466 0.7605 3630019 CBKinase1_019971 CC(=O)N(c1ccc2oc3CCCCc3c2c1)S(=O)(=O)c4cccc5cccnc45 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K14 compound treatment 2066049.0 391000.0 0.66 1416899.0 -332000.0 -0.54 0.0832 0.0972 3630020 CBKinase1_019972 CCc1c(C)sc(NC(=S)Nc2cccnc2)c1C(=O)OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K15 mock treatment 1726366.0 51000.0 0.09 2014007.0 265000.0 0.43 0.3686 0.8313 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K16 mock treatment 1983800.0 308000.0 0.52 2012732.0 264000.0 0.43 0.6752 0.9957 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K17 compound treatment 1810254.0 135000.0 0.23 1806348.0 57700.0 0.09 0.2283 0.9239 3630021 CBKinase1_019973 Cc1cc(C)nc(SCC(=O)Nc2ccc(cc2)N3CCOCC3)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K18 compound treatment 1696616.0 21300.0 0.04 1709693.0 -38900.0 -0.06 -0.0197 -0.2687 3630022 CBKinase1_019974 CC1=C(C(NC(=S)N1)c2cc(Br)ccc2OCC(=O)N)C(=O)Nc3ccccc3Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K19 compound treatment 1534683.0 -141000.0 -0.24 1846275.0 97600.0 0.16 -0.0552 -0.1925 3630023 CBKinase1_019975 COc1ccc(cc1)c2nnc(SCC(=O)Nc3ccc(Br)c(C)c3C)[nH]2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K20 compound treatment 1645581.0 -29800.0 -0.05 1880345.0 132000.0 0.22 0.117 0.5278 3630024 CBKinase1_019976 Cc1ccccc1NC(=O)CSc2ncnc3scc(c4ccc(Cl)cc4)c23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K21 compound treatment 1824165.0 149000.0 0.25 1947720.0 199000.0 0.33 0.4088 0.9918 3630025 CBKinase1_019977 Cc1ccc(NC(=O)CC2N(CCNC2=O)C(=S)Nc3ccccc3)c(C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K22 compound treatment 1876781.0 201000.0 0.34 1914680.0 166000.0 0.27 0.4335 0.9938 3630026 CBKinase1_019978 Cc1ccccc1OCc2nn3c(COc4ccccc4)nnc3s2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K23 mock treatment 2150219.0 475000.0 0.8 1712627.0 -36000.0 -0.06 0.5266 0.6534 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 K24 mock treatment 1757397.0 82000.0 0.14 1546195.0 -202000.0 -0.33 -0.1364 -0.3793 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L01 compound treatment 1292004.0 -383000.0 -0.65 1133882.0 -615000.0 -1.01 -1.1713 -0.9774 3630027 CBKinase1_019979 COc1ccc(Cl)cc1C(=O)N(Cc2nc(no2)c3ccc(C)cc3)C(C)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L02 compound treatment 1590216.0 -85100.0 -0.14 1259714.0 -489000.0 -0.8 -0.6685 -0.8211 3630028 CBKinase1_019980 OCCN1CCN(CC1)C(=S)NCc2ccco2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L03 compound treatment 1415303.0 -260000.0 -0.44 1815461.0 66800.0 0.11 -0.2338 -0.5155 3630029 CBKinase1_019981 COc1ccc(cc1)c2nnc(SCc3ccc(OC)c(c3)[N+](=O)[O-])n2c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L04 compound treatment 1505212.0 -170000.0 -0.29 1791988.0 43400.0 0.07 -0.1534 -0.5171 3630030 CBKinase1_019982 CCc1ccc(OCC(=O)NC(=S)Nc2cccc3nsnc23)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L05 compound treatment 1633216.0 -42100.0 -0.07 1838763.0 90100.0 0.15 0.054 0.3292 3630031 CBKinase1_019983 CCOc1ccc(cc1)c2nnc(SCC(=O)O)n2c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L06 compound treatment 1802944.0 128000.0 0.22 1845624.0 97000.0 0.16 0.2651 0.9886 3630032 CBKinase1_019984 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2ccccc2Br 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L07 mock treatment 1797565.0 122000.0 0.21 1818312.0 69700.0 0.11 0.227 0.9608 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L08 mock treatment 1857723.0 182000.0 0.31 1983512.0 235000.0 0.38 0.4905 0.994 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L09 compound treatment 1747930.0 72600.0 0.12 2122201.0 374000.0 0.61 0.5198 0.8324 3630033 CBKinase1_019985 COc1cccc(c1)S(=O)(=O)Nc2ccc(cc2)C(=O)Nc3ccc4OCCOc4c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L10 compound treatment 1882434.0 207000.0 0.35 2060892.0 312000.0 0.51 0.6097 0.983 3630034 CBKinase1_019986 COC(=O)c1ccccc1NC(=O)CSc2nnc(c3ccc(OC)cc3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L11 compound treatment 1901890.0 227000.0 0.38 1992705.0 244000.0 0.4 0.554 0.9998 3630035 CBKinase1_019987 COc1cccc2cc(oc12)c3nnc(SCC(=O)Nc4cccc(SC)c4)n3C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L12 compound treatment 1940446.0 265000.0 0.45 2028415.0 280000.0 0.46 0.6415 0.9999 3630036 CBKinase1_019988 CCOc1ccc2nc(SCC(=O)Nc3ccc(Br)cc3Cl)sc2c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L13 compound treatment 2012816.0 337000.0 0.57 2243042.0 494000.0 0.81 0.9769 0.9854 3630037 CBKinase1_019989 COC(=O)c1sccc1NC(=O)CSc2nnnn2c3ccccc3C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L14 compound treatment 1891793.0 216000.0 0.37 2134285.0 386000.0 0.63 0.706 0.9664 3630038 CBKinase1_019990 Clc1cccc(c1)S(=O)(=O)NCC(=O)Nc2sc3CCCCc3c2C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L15 mock treatment 1933950.0 259000.0 0.44 2044956.0 296000.0 0.49 0.6529 0.9987 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L16 mock treatment 1422717.0 -253000.0 -0.43 1897337.0 149000.0 0.24 -0.1301 -0.2642 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L17 compound treatment 1633355.0 -42000.0 -0.07 1751402.0 2770.0 0.0 -0.0471 -0.6606 3630039 CBKinase1_019991 CN(C)c1nc(N)nc(CSc2ncc(Cl)cc2Cl)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L18 compound treatment 1748620.0 73300.0 0.12 1423323.0 -325000.0 -0.53 -0.2893 -0.5285 3630040 CBKinase1_019992 CC(=O)Nc1ccc(Br)cc1c2nc3ccccc3nc2OCc4ccc(Cl)cc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L19 compound treatment 1775145.0 99800.0 0.17 2199187.0 451000.0 0.74 0.6416 0.847 3630041 CBKinase1_019993 NC(=O)c1c(NC(=O)CSc2nc[nH]n2)sc3CCCc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L20 compound treatment 1861303.0 186000.0 0.31 1933789.0 185000.0 0.3 0.4371 0.9998 3630042 CBKinase1_019994 Cc1ccc(cc1S(=O)(=O)NCC2CCCO2)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L21 compound treatment 1616519.0 -58800.0 -0.1 1671907.0 -76700.0 -0.13 -0.1593 -0.9933 3630043 CBKinase1_019995 OCCNC(=O)c1nc(NCCO)c2ccccc2n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L22 compound treatment 1675429.0 68.8 0.0 1742070.0 -6560.0 -0.01 -0.0075 -0.6994 1754864 CBKinase1_019996 CCn1c(SCC(=O)N2CCc3ccccc23)nnc1c4ccco4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L23 mock treatment 1542453.0 -133000.0 -0.22 1731556.0 -17100.0 -0.03 -0.1789 -0.789 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 L24 mock treatment 1728385.0 53000.0 0.09 1238237.0 -510000.0 -0.84 -0.528 -0.6276 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M01 compound treatment 1156241.0 -519000.0 -0.88 1126050.0 -623000.0 -1.02 -1.3428 -0.9972 3630044 CBKinase1_019997 FC(F)(F)c1nc2ccccc2n1CC(=O)NCCN3CCCC3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M02 compound treatment 1305567.0 -370000.0 -0.63 1355926.0 -393000.0 -0.64 -0.8977 -0.9999 3630045 CBKinase1_019998 COc1cc(OC)c(NC(=O)CSc2nnc(c3ccccc3)n2C)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M03 compound treatment 1310047.0 -365000.0 -0.62 1310892.0 -438000.0 -0.72 -0.9445 -0.9973 3630046 CBKinase1_019999 Cc1c(Cl)cccc1NC(=O)CSc2nnc(c3ccc(NC(=O)c4ccccc4Br)cc3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M04 compound treatment 1396031.0 -279000.0 -0.47 1660629.0 -88000.0 -0.14 -0.4363 -0.8826 3630047 CBKinase1_020000 Nc1ccc(cc1)c2nnc(SCC(=O)c3ccc(F)cc3)n2c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M05 compound treatment 1479549.0 -196000.0 -0.33 1689299.0 -59300.0 -0.1 -0.3031 -0.8776 3630048 CBKinase1_020001 COc1cccc2cc(oc12)c3nnc(SCC(=O)Nc4sc5CCCCc5c4C#N)n3C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M06 compound treatment 1695775.0 20400.0 0.03 1521689.0 -227000.0 -0.37 -0.2386 -0.6387 3630049 CBKinase1_020002 CCn1c(SCC(=O)Nc2ccc3OCCOc3c2)nnc1c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M07 compound treatment 1436457.0 -239000.0 -0.4 1497050.0 -252000.0 -0.41 -0.5775 -1.0 3630050 CBKinase1_020003 CCOc1ccc(NC(=O)C2CC(=O)N=C(N2)N3CCN(C)CC3)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M08 compound treatment 1219692.0 -456000.0 -0.77 1514934.0 -234000.0 -0.38 -0.8162 -0.9478 3630051 CBKinase1_020004 CCn1c(SCC(=O)Nc2sc3CC(CCc3c2C#N)C(C)(C)C)nnc1c4cccc(C)c4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M09 mock treatment 1377316.0 -298000.0 -0.5 1766313.0 17700.0 0.03 -0.3362 -0.6654 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M10 mock treatment 1607649.0 -67700.0 -0.11 1424434.0 -324000.0 -0.53 -0.4567 -0.8403 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M11 compound treatment 1754613.0 79300.0 0.13 1659404.0 -89200.0 -0.15 -0.0085 -0.043 3630052 CBKinase1_020005 CCCC(=O)n1nc(nc1NCc2ccco2)c3ccc(Cl)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M12 compound treatment 1612259.0 -63100.0 -0.11 1751759.0 3130.0 0.01 -0.0719 -0.6724 3630053 CBKinase1_020006 CS(=O)(=O)N(CC(=O)Nc1ccc(F)c(F)c1)c2ccccc2Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M13 mock treatment 1535652.0 -140000.0 -0.24 1740459.0 -8170.0 -0.01 -0.1767 -0.746 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M14 mock treatment 1620517.0 -54800.0 -0.09 1814461.0 65800.0 0.11 0.0106 0.0748 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M15 compound treatment 1582221.0 -93100.0 -0.16 1733977.0 -14700.0 -0.02 -0.1285 -0.8055 3630054 CBKinase1_020007 COc1ccc(NC(=S)Nc2cccc(Cn3cc(Cl)cn3)c2)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M16 compound treatment 1462365.0 -213000.0 -0.36 1453885.0 -295000.0 -0.48 -0.5965 -0.9896 3630055 CBKinase1_020008 Cc1sc2ncn(CC(=O)NCc3ccco3)c(=O)c2c1c4ccc(Cl)cc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M17 compound treatment 1506875.0 -168000.0 -0.29 1669565.0 -79100.0 -0.13 -0.2933 -0.9363 3630056 CBKinase1_020009 CC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cccc4cccnc34)cc12 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M18 compound treatment 1657135.0 -18200.0 -0.03 1531196.0 -217000.0 -0.36 -0.2738 -0.7655 3630057 CBKinase1_020010 CC(Sc1nnc(c2ccc(Br)cc2)n1c3ccccc3)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M19 compound treatment 1711514.0 36200.0 0.06 1673549.0 -75100.0 -0.12 -0.0437 -0.3182 3630058 CBKinase1_020011 O=C(Cn1cc(C(=O)c2cccs2)c3ccccc13)Nc4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M20 compound treatment 1615259.0 -60100.0 -0.1 1720987.0 -27600.0 -0.05 -0.104 -0.9336 3630059 CBKinase1_020012 Cn1c(SCC(=O)O)nnc1c2ccccc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M21 compound treatment 1680732.0 5370.0 0.01 1628027.0 -121000.0 -0.2 -0.1333 -0.6739 3630060 CBKinase1_020013 Cc1ccc(cc1)c2noc(CSc3nc(=O)c(C)c(C)[nH]3)n2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M22 compound treatment 1570568.0 -105000.0 -0.18 1462377.0 -286000.0 -0.47 -0.4572 -0.9115 3630061 CBKinase1_020014 Clc1ccc(NC(=O)NCCCN2CCCC2=O)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M23 compound treatment 1649940.0 -25400.0 -0.04 1374129.0 -375000.0 -0.61 -0.4644 -0.7548 3630062 CBKinase1_020015 CC(C)(C)c1ccc(NC(=O)CCSc2nnnn2c3ccccc3)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 M24 compound treatment 1316176.0 -359000.0 -0.61 910956.0 -838000.0 -1.37 -1.4007 -0.9329 3630063 CBKinase1_020016 OC(=O)c1cc2cc(CSCCC#N)ccc2o1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N01 compound treatment 1059391.0 -616000.0 -1.04 1224633.0 -524000.0 -0.86 -1.3445 -0.9954 3630064 CBKinase1_020017 OCCCNC(=O)c1ccccc1c2ccccc2C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N02 compound treatment 1110858.0 -565000.0 -0.96 1022409.0 -726000.0 -1.19 -1.5173 -0.9941 3630065 CBKinase1_020018 CCOC(=O)c1c(C)c(C)sc1NC(=O)CSc2nc(C)nc3sc4CCCc4c23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N03 compound treatment 1029936.0 -645000.0 -1.09 1564911.0 -184000.0 -0.3 -0.9854 -0.8696 3630066 CBKinase1_020019 COC(=O)c1ccccc1NC(=O)COc2ccccc2F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N04 compound treatment 1252967.0 -422000.0 -0.71 1338442.0 -410000.0 -0.67 -0.9809 -0.9995 3630067 CBKinase1_020020 CCOC(=O)C1=C(C)NC(=S)NC1c2cc(I)c(OCC#N)c(OC)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N05 compound treatment 1301787.0 -374000.0 -0.63 1370811.0 -378000.0 -0.62 -0.885 -0.9999 3630068 CBKinase1_020021 COc1ccc(NC(=O)c2ccco2)cc1NC(=S)NC(=O)c3cc4ccccc4o3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N06 compound treatment 1237042.0 -438000.0 -0.74 1355235.0 -393000.0 -0.64 -0.9805 -0.9976 3630069 CBKinase1_020022 COc1ccc(Oc2coc3cc(OC(=O)CN4C(=O)c5ccccc5C4=O)ccc3c2=O)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N07 compound treatment 1483086.0 -192000.0 -0.33 1361830.0 -387000.0 -0.63 -0.6784 -0.952 3630070 CBKinase1_020023 CCc1ccc(OCC(=O)Nc2ccccc2c3nc4ccccc4s3)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N08 compound treatment 1433339.0 -242000.0 -0.41 1361320.0 -387000.0 -0.63 -0.7385 -0.9776 3630071 CBKinase1_020024 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N09 mock treatment 1232973.0 -442000.0 -0.75 1102249.0 -646000.0 -1.06 -1.2786 -0.9856 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N10 mock treatment 1167039.0 -508000.0 -0.86 1362134.0 -386000.0 -0.63 -1.0563 -0.9886 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N11 compound treatment 1593069.0 -82300.0 -0.14 1348054.0 -401000.0 -0.66 -0.5627 -0.8385 3630072 CBKinase1_020025 Cc1cc(C)c(cc1C)c2csc(Cc3nc(cs3)c4cc5ccccc5oc4=O)n2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N12 compound treatment 1502292.0 -173000.0 -0.29 1681588.0 -67000.0 -0.11 -0.2848 -0.9104 3630073 CBKinase1_020026 Cc1cc(SCC(=O)N2CCC(CC2)c3noc4ccc(F)cc34)nc5ccccc15 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N13 mock treatment 1494635.0 -181000.0 -0.31 1468094.0 -281000.0 -0.46 -0.5414 -0.9804 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N14 mock treatment 1351359.0 -324000.0 -0.55 1236405.0 -512000.0 -0.84 -0.9814 -0.9787 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N15 compound treatment 1323456.0 -352000.0 -0.6 1455521.0 -293000.0 -0.48 -0.7609 -0.9943 3630074 CBKinase1_020027 COc1ccc(cc1)C2(CCOCC2)C(=O)NCCN3CCOCC3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N16 compound treatment 1351465.0 -324000.0 -0.55 1299556.0 -449000.0 -0.74 -0.9081 -0.9895 3630075 CBKinase1_020028 COc1ccccc1NC(=O)C2=C(C)NC(=S)NC2c3ccccc3OCC(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N17 compound treatment 1117420.0 -558000.0 -0.94 1091169.0 -657000.0 -1.08 -1.4297 -0.9978 3630076 CBKinase1_020029 COc1ccc(NC(=O)c2ccco2)cc1NC(=O)COc3cc(C)c(Cl)c(C)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N18 compound treatment 1292957.0 -382000.0 -0.65 1624067.0 -125000.0 -0.2 -0.6021 -0.887 3630077 CBKinase1_020030 Cc1ccc(cc1)C(=O)NCCCNc2ccccc2[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N19 compound treatment 1397285.0 -278000.0 -0.47 1606411.0 -142000.0 -0.23 -0.4976 -0.9475 3630078 CBKinase1_020031 CC(NS(=O)(=O)c1cccc(Cl)c1)C(=O)Nc2ccc(Br)cc2F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N20 compound treatment 1445280.0 -230000.0 -0.39 1315143.0 -433000.0 -0.71 -0.7777 -0.96 3630079 CBKinase1_020032 CCOc1cc(cc(Br)c1O)C2NC(=S)NC(=C2C(=O)Nc3ccccc3C(=O)OC)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N21 compound treatment 1331349.0 -344000.0 -0.58 1245778.0 -503000.0 -0.82 -0.9945 -0.9855 3630080 CBKinase1_020033 CN(CC(=O)Nc1cc(ccc1C)[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N22 compound treatment 1326121.0 -349000.0 -0.59 1185178.0 -563000.0 -0.92 -1.071 -0.9768 3630081 CBKinase1_020034 COc1ccc(cc1)n2c(SCC(=O)N)nnc2c3cccs3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N23 compound treatment 1429054.0 -246000.0 -0.42 1079511.0 -669000.0 -1.1 -1.0702 -0.9122 3630082 CBKinase1_020035 COc1cc(cc(Cl)c1OCC(=O)N)C2NC(=O)NC(=C2C(=O)c3ccccc3)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 N24 compound treatment 1394126.0 -281000.0 -0.48 956070.0 -793000.0 -1.3 -1.2551 -0.9072 1488938 CBKinase1_020036 Fc1ccc(cc1)N2C(=O)CC(SCC(=O)Nc3ccc(Br)cc3)C2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O01 compound treatment 859588.0 -816000.0 -1.38 947078.0 -802000.0 -1.31 -1.9053 -0.9997 3630083 CBKinase1_020037 COc1ccc(NC(=O)CSc2nccc(O)n2)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O02 compound treatment 1093735.0 -582000.0 -0.98 922915.0 -826000.0 -1.35 -1.6531 -0.9878 3630084 CBKinase1_020038 Cc1ccc(cc1[N+](=O)[O-])C(=O)CSc2nc3ccccc3o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O03 compound treatment 1284476.0 -391000.0 -0.66 1097520.0 -651000.0 -1.07 -1.2224 -0.9736 3630085 CBKinase1_020039 CC(=O)Nc1ccc(NC(=O)CSc2nccc(O)n2)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O04 compound treatment 1360784.0 -315000.0 -0.53 1195832.0 -553000.0 -0.91 -1.0171 -0.9679 1974377 CBKinase1_020040 Cc1nc(SCC(=O)c2ccc3OCCOc3c2)c4c5CCCc5sc4n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O05 compound treatment 1178122.0 -497000.0 -0.84 1422473.0 -326000.0 -0.53 -0.9731 -0.976 3630086 CBKinase1_020041 COc1ccc(NC(=S)NC(=O)C(C)Oc2ccc(Cl)cc2Cl)c(c1)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O06 compound treatment 1265926.0 -409000.0 -0.69 1329731.0 -419000.0 -0.69 -0.9755 -1.0 3630087 CBKinase1_020042 COc1ccc(NC(=O)c2ccco2)cc1NC(=S)NC(=O)c3ccc(o3)c4cccc(Cl)c4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O07 compound treatment 1173542.0 -502000.0 -0.85 1140838.0 -608000.0 -1.0 -1.305 -0.9969 1576233 CBKinase1_020043 Cc1ccc(NC(=O)Cn2c(nc3ccccc23)c4nonc4N)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O08 compound treatment 1189486.0 -486000.0 -0.82 1146829.0 -602000.0 -0.99 -1.279 -0.9959 3630088 CBKinase1_020044 Cc1ccc(NC(=O)C2CC(=O)n3c(N2)nc4ccccc34)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O09 compound treatment 1264037.0 -411000.0 -0.7 1196729.0 -552000.0 -0.9 -1.1319 -0.9916 3042354 CBKinase1_020045 Brc1ccc(cc1)C(=O)CCC(=O)Nc2cccnc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O10 compound treatment 1255289.0 -420000.0 -0.71 1328978.0 -420000.0 -0.69 -0.9891 -0.9999 3630089 CBKinase1_020046 CC(C)(C)NC(=O)Cn1cc(C(=O)c2ccco2)c3ccccc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O11 mock treatment 1224773.0 -451000.0 -0.76 1313938.0 -435000.0 -0.71 -1.0431 -0.9994 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O12 mock treatment 1302929.0 -372000.0 -0.63 1253670.0 -495000.0 -0.81 -1.0194 -0.9922 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O13 compound treatment 1278058.0 -397000.0 -0.67 1338035.0 -411000.0 -0.67 -0.9514 -1.0 3630090 CBKinase1_020047 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)Nc3cc(ccc3Cl)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O14 compound treatment 1082468.0 -593000.0 -1.0 1193328.0 -555000.0 -0.91 -1.3532 -0.9988 3630091 CBKinase1_020048 COc1ccc(OC)c(NC(=O)CSc2nc(nc3CC(C)(C)OCc23)c4ccccc4)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O15 compound treatment 1330786.0 -345000.0 -0.58 1996724.0 248000.0 0.41 -0.1249 -0.1757 3630092 CBKinase1_020049 Cc1oc2cc(OCC(=O)Nc3ccccc3F)ccc2c(=O)c1c4ccc(F)cc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O16 compound treatment 1267222.0 -408000.0 -0.69 1162685.0 -586000.0 -0.96 -1.1675 -0.9869 3630093 CBKinase1_020050 COc1ccc(CCNc2nc(cs2)c3cccc(NC(=O)C)c3)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O17 compound treatment 1193873.0 -481000.0 -0.82 1014528.0 -734000.0 -1.2 -1.427 -0.982 3630094 CBKinase1_020051 CCC(CO)NS(=O)(=O)c1ccc(OC)c(c1)c2nnc3c4ccccc4c(C)nn23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O18 compound treatment 1199946.0 -475000.0 -0.8 1206498.0 -542000.0 -0.89 -1.1973 -0.9988 3630095 CBKinase1_020052 O=C(CSc1nc[nH]n1)Nc2sccc2C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O19 compound treatment 1709699.0 34300.0 0.06 1572536.0 -176000.0 -0.29 -0.163 -0.5536 3630096 CBKinase1_020053 CCOC(=O)c1ccc(NC(=O)CSc2nccc(O)n2)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O20 compound treatment 1440408.0 -235000.0 -0.4 1529474.0 -219000.0 -0.36 -0.5352 -0.9987 3630097 CBKinase1_020054 CN(C(=O)CSc1nc(N)c2c3CC(C)(C)SCc3sc2n1)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O21 compound treatment 1233253.0 -442000.0 -0.75 1406704.0 -342000.0 -0.56 -0.9254 -0.9898 1416715 CBKinase1_020055 COC(=O)c1ccccc1NC(=O)NCc2ccco2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O22 compound treatment 1361345.0 -314000.0 -0.53 1107102.0 -642000.0 -1.05 -1.1193 -0.9501 3630098 CBKinase1_020056 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)NC2CCCC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O23 compound treatment 1487655.0 -188000.0 -0.32 1260887.0 -488000.0 -0.8 -0.7899 -0.9183 3630099 CBKinase1_020057 COc1ccc(NC(=O)C(=O)NCc2cccnc2)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 O24 compound treatment 1115331.0 -560000.0 -0.95 1012642.0 -736000.0 -1.21 -1.5232 -0.9929 3630100 CBKinase1_020058 CN(CC(=O)Nc1c(C)cc(C)cc1C)S(=O)(=O)c2ccc(Br)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P01 compound treatment 743508.0 -932000.0 -1.58 749108.0 -1000000.0 -1.64 -2.2737 -0.9998 3630101 CBKinase1_020059 [O-][N+](=O)c1ccc(OCC(=O)Nc2cccc(c2)c3nc4c(ccc5ccccc45)o3)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P02 compound treatment 754646.0 -921000.0 -1.56 690117.0 -1060000.0 -1.73 -2.3287 -0.9986 3630102 CBKinase1_020060 CCc1nc(SCC(=O)Nc2ccc(OC)cc2)c3c4CC(C)(C)OCc4sc3n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P03 compound treatment 950930.0 -724000.0 -1.23 807886.0 -941000.0 -1.54 -1.9573 -0.9936 1820979 CBKinase1_020061 O=C(CSc1nnc(c2ccco2)n1c3ccccc3)N4CCc5ccccc45 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P04 compound treatment 1127502.0 -548000.0 -0.93 843407.0 -905000.0 -1.48 -1.7048 -0.9744 3630103 CBKinase1_020062 COc1ccc(cc1)c2nnc(SCC(=O)Nc3ccc4ccccc4c3)[nH]2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P05 compound treatment 923472.0 -752000.0 -1.27 1005354.0 -743000.0 -1.22 -1.7613 -0.9998 3630104 CBKinase1_020063 FC(F)(F)c1cccc(NC(=O)Cn2cnc3sc(cc3c2=O)c4ccccc4)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P06 compound treatment 962259.0 -713000.0 -1.21 861874.0 -887000.0 -1.45 -1.8812 -0.9957 3630105 CBKinase1_020064 CCc1ccc(CCC(=O)Nc2sc3CCCCc3c2C#N)o1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P07 compound treatment 955935.0 -719000.0 -1.22 965573.0 -783000.0 -1.28 -1.7686 -0.9997 3630106 CBKinase1_020065 Cn1c(SCC(=O)Nc2cccc(c2)C(=O)O)nnc1c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P08 compound treatment 1030383.0 -645000.0 -1.09 889875.0 -859000.0 -1.41 -1.7672 -0.9921 3630107 CBKinase1_020066 COc1ccc(NC(=O)Cc2nc(cs2)c3ccc(cc3)[N+](=O)[O-])cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P09 compound treatment 920615.0 -755000.0 -1.28 819911.0 -929000.0 -1.52 -1.9796 -0.9962 3630108 CBKinase1_020067 CCn1c(SCC(=O)Nc2cccc(C)c2C)nnc1c3cccs3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P10 compound treatment 999053.0 -676000.0 -1.14 1001132.0 -747000.0 -1.23 -1.6757 -0.9994 2069037 CBKinase1_020068 Cc1cccc(c1C)n2c(SCC(=O)O)nnc2c3cccs3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P11 mock treatment 1181566.0 -494000.0 -0.84 877406.0 -871000.0 -1.43 -1.6007 -0.9675 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P12 mock treatment 1084097.0 -591000.0 -1.0 1009963.0 -739000.0 -1.21 -1.5637 -0.9955 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P13 compound treatment 949374.0 -726000.0 -1.23 921621.0 -827000.0 -1.36 -1.8273 -0.9988 3630109 CBKinase1_020069 CC(C)(C)c1ccc(cc1)S(=O)(=O)NCC(=O)Nc2cccc(Cl)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P14 compound treatment 926552.0 -749000.0 -1.27 899529.0 -849000.0 -1.39 -1.8803 -0.9989 3630110 CBKinase1_020070 O=C(NCCCN1CCOCC1)C(=O)NC2CC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P15 compound treatment 968036.0 -707000.0 -1.2 1032267.0 -716000.0 -1.17 -1.6768 -1.0 3630111 CBKinase1_020071 COc1ccccc1N2C(=O)CC(SCC(=O)Nc3ccc(F)cc3)C2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P16 compound treatment 879781.0 -796000.0 -1.35 895936.0 -853000.0 -1.4 -1.9404 -0.9998 3630112 CBKinase1_020072 COC(=O)c1ccccc1NC(=O)Cn2c(C)ncc2[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P17 compound treatment 1014547.0 -661000.0 -1.12 973123.0 -776000.0 -1.27 -1.6897 -0.998 3630113 CBKinase1_020073 Fc1ccc(NC(=O)c2ccc(OCC(=O)Nc3ccccc3C(F)(F)F)cc2)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P18 compound treatment 958227.0 -717000.0 -1.21 1067314.0 -681000.0 -1.12 -1.6479 -0.9991 3630114 CBKinase1_020074 COc1ccc(NC(=O)CSc2ncn(n2)c3ccccc3)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P19 compound treatment 1020232.0 -655000.0 -1.11 1043946.0 -705000.0 -1.15 -1.6008 -0.9998 3630115 CBKinase1_020075 COc1cc(OC)c(NC(=O)CSc2nnc(C)s2)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P20 compound treatment 1254097.0 -421000.0 -0.71 1004463.0 -744000.0 -1.22 -1.3666 -0.9673 3630116 CBKinase1_020076 Cc1cc(ccc1NC(=O)CSc2nnc(o2)c3ccc(Br)cc3)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P21 compound treatment 1122974.0 -552000.0 -0.94 1030476.0 -718000.0 -1.18 -1.4934 -0.9935 3630117 CBKinase1_020077 CNc1nc(NC(C)C)nc(Oc2ccc(O)nn2)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P22 compound treatment 1074078.0 -601000.0 -1.02 875598.0 -873000.0 -1.43 -1.7314 -0.9861 3630118 CBKinase1_020078 CNC(=O)CN(C)S(=O)(=O)c1ccc(OC)c(C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P23 compound treatment 1001904.0 -673000.0 -1.14 742664.0 -1010000.0 -1.65 -1.9719 -0.9838 3630119 CBKinase1_020079 CCN1CCN(CC1)C(=O)c2ccc(CNS(=O)(=O)c3cccc(OC)c3)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2386 P24 compound treatment 907539.0 -768000.0 -1.3 808108.0 -941000.0 -1.54 -2.009 -0.9964 3630120 CBKinase1_020080 Cc1ccc2cccc(OCc3nnc(SCC(=O)O)n3C)c2n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A01 compound treatment 1487218.0 -480000.0 -0.81 1373977.0 -745000.0 -1.22 -1.4378 -0.9804 3630741 CBKinase1_020721 C(Sc1nccn1Cc2ccccc2)c3nnc(o3)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A02 compound treatment 1636403.0 -331000.0 -0.56 1699524.0 -419000.0 -0.69 -0.882 -0.9948 3041125 CBKinase1_020722 COC(=O)c1ccccc1NC(=O)C2CC(=NO2)c3cccc(Br)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A03 compound treatment 1878374.0 -88800.0 -0.15 1772871.0 -346000.0 -0.57 -0.5073 -0.8647 3630742 CBKinase1_020723 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(NC(=O)c3ccco3)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A04 compound treatment 1972052.0 4870.0 0.01 2062626.0 -56300.0 -0.09 -0.0594 -0.6414 3630743 CBKinase1_020724 Brc1cccc(c1)C2=NOC(C2)C(=O)NCc3ccccn3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A05 compound treatment 1640055.0 -327000.0 -0.55 1590940.0 -528000.0 -0.87 -1.0034 -0.9767 3630744 CBKinase1_020725 COc1cc(NC(=O)CN(C)S(=O)(=O)c2ccc3ccccc3c2)cc(OC)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A06 compound treatment 1781132.0 -186000.0 -0.31 1802446.0 -316000.0 -0.52 -0.5894 -0.9714 3630745 CBKinase1_020726 Oc1ccccc1C2=NOC(C2)C(=O)Nc3cccnc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A07 compound treatment 1599527.0 -368000.0 -0.62 1411310.0 -708000.0 -1.16 -1.2601 -0.9574 3630746 CBKinase1_020727 CN(CC(=O)Nc1ccccc1c2ccccc2)S(=O)(=O)c3ccc4ccccc4c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A08 compound treatment 1743759.0 -223000.0 -0.38 1545286.0 -574000.0 -0.94 -0.9322 -0.9199 3630747 CBKinase1_020728 Cc1cc(NC(=O)c2cc(on2)c3ccccc3)n(n1)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A09 compound treatment 1150161.0 -817000.0 -1.38 1018142.0 -1100000.0 -1.8 -2.2536 -0.9914 1675793 CBKinase1_020729 CN(C)CCNc1nc(c(Cl)s1)S(=O)(=O)c2ccc(C)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A10 compound treatment 2132405.0 165000.0 0.28 2366003.0 247000.0 0.4 0.4841 0.9837 3630748 CBKinase1_020730 CCOC(=O)c1sc(NC(=O)c2cc(on2)c3ccccc3)c(C(=O)OCC)c1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A11 compound treatment 2413932.0 447000.0 0.76 1879591.0 -239000.0 -0.39 0.2574 0.3021 3630749 CBKinase1_020731 O=C(COc1ccccc1C(=O)Nc2ccccc2C#N)Nc3ccc4c(c3)oc5ccccc54 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A12 compound treatment 1735516.0 -232000.0 -0.39 1910596.0 -208000.0 -0.34 -0.5187 -0.9976 3630750 CBKinase1_020732 CC1(C)CC2=C(C(=O)C1)C(NC(=O)c3ccccc3)(C(=O)N2CCCN4CCOCC4)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A13 mock treatment 1855331.0 -112000.0 -0.19 1887906.0 -231000.0 -0.38 -0.4016 -0.9487 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A14 mock treatment 1904617.0 -62600.0 -0.11 1945326.0 -174000.0 -0.28 -0.2761 -0.9094 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A15 compound treatment 1854758.0 -112000.0 -0.19 1913309.0 -206000.0 -0.34 -0.3728 -0.9634 3630751 CBKinase1_020733 CC(C)OC(=O)CSc1nc(cc(c1C#N)C(F)(F)F)c2ccccc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A16 compound treatment 1613322.0 -354000.0 -0.6 1765969.0 -353000.0 -0.58 -0.8326 -0.9998 3630752 CBKinase1_020734 O=C(CSc1nc(ccc1C#N)c2cccs2)Nc3sc4CCCCc4c3C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A17 compound treatment 1611796.0 -355000.0 -0.6 1544436.0 -574000.0 -0.94 -1.0911 -0.9766 3630753 CBKinase1_020735 Nc1cc(N)nc(SCC(=O)Nc2cccc(c2)C(F)(F)F)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A18 compound treatment 1850465.0 -117000.0 -0.2 2149201.0 30300.0 0.05 -0.1046 -0.5136 3630754 CBKinase1_020736 CCOC(=O)c1sc(NC(=O)CSc2nc3CCCc3cc2C#N)c(C#N)c1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A19 compound treatment 1587241.0 -380000.0 -0.64 1572763.0 -546000.0 -0.9 -1.0877 -0.9868 3630755 CBKinase1_020737 CN1CCc2nc(SCC(=O)Nc3cccc(F)c3)c(C#N)c(c4ccccc4)c2C1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A20 compound treatment 5077522.0 3110000.0 5.26 4856506.0 2740000.0 4.49 6.8953 0.9968 3630756 CBKinase1_020738 COc1ccc(cc1)c2ccc(C#N)c(SCC(=O)Nc3cc(OC)c(OC)c(OC)c3)n2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A21 compound treatment 1503025.0 -464000.0 -0.79 1647273.0 -472000.0 -0.77 -1.1021 -1.0 3630757 CBKinase1_020739 Fc1cccc(NC(=O)CSc2nc3CCCCc3cc2C#N)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A22 compound treatment 1479803.0 -487000.0 -0.82 1760430.0 -358000.0 -0.59 -0.9988 -0.9862 3119742 CBKinase1_020740 OC(=O)CCSc1nc(cc(c1C#N)C(F)(F)F)C2(CC3CC4CC(C3)C2)C4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A23 compound treatment 1792587.0 -175000.0 -0.3 1479251.0 -640000.0 -1.05 -0.9503 -0.8724 3630758 CBKinase1_020741 COc1ccc(NC(=O)CN2CCN(CC2)S(=O)(=O)N(C)C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 A24 compound treatment 1518531.0 -449000.0 -0.76 1482578.0 -636000.0 -1.04 -1.2744 -0.9879 3119273 CBKinase1_020742 CC(Sc1nc(ccc1C#N)c2cccnc2)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B01 compound treatment 1449885.0 -517000.0 -0.88 1632553.0 -486000.0 -0.8 -1.1828 -0.9989 3630759 CBKinase1_020743 COc1cc(CO)ccc1OCC(=O)Nc2ccc(Br)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B02 compound treatment 2123724.0 157000.0 0.26 1921124.0 -198000.0 -0.32 -0.0419 -0.1 3630760 CBKinase1_020744 CNc1nc(OCC#N)nc(n1)N2CCCCC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B03 compound treatment 1891150.0 -76000.0 -0.13 2138052.0 19100.0 0.03 -0.0688 -0.5197 3630761 CBKinase1_020745 COc1cc(cc(I)c1OCCO)C2NC(=S)NC(=C2C(=O)c3ccccc3)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B04 compound treatment 1886803.0 -80400.0 -0.14 2303662.0 185000.0 0.3 0.1179 0.3551 3211403 CBKinase1_020746 Cc1ccc(cc1)N2CC(CC2=O)C(=O)NCc3ccccn3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B05 compound treatment 2186471.0 219000.0 0.37 2088906.0 -30000.0 -0.05 0.2277 0.6081 3630762 CBKinase1_020747 Cc1ccc(NC(=O)COc2ccc(Br)cc2CO)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B06 compound treatment 2123506.0 156000.0 0.26 2344057.0 225000.0 0.37 0.448 0.9867 3630763 CBKinase1_020748 Cc1ccnc(NC(=O)COc2ccc(Cl)cc2)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B07 compound treatment 2163174.0 196000.0 0.33 1993929.0 -125000.0 -0.2 0.0897 0.2301 3630764 CBKinase1_020749 COC(=O)c1ccc(NC(=O)CSc2nnc(c3cccs3)n2c4ccc(OC)cc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B08 compound treatment 2194771.0 228000.0 0.39 2290053.0 171000.0 0.28 0.4707 0.9878 3630765 CBKinase1_020750 Cc1ccccc1c2nnc(SCC(=O)Nc3ccc(Oc4ccccc4)cc3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B09 compound treatment 2182079.0 215000.0 0.36 2271270.0 152000.0 0.25 0.4338 0.9831 3630766 CBKinase1_020751 Cc1nc(SCC(=O)Nc2ccc(cc2)[N+](=O)[O-])nc(O)c1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B10 compound treatment 2230651.0 263000.0 0.45 2431731.0 313000.0 0.51 0.6778 0.9976 3630767 CBKinase1_020752 COc1ccc(cc1OC)C(=O)CSc2nnc(c3ccccc3Cl)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B11 compound treatment 2207741.0 241000.0 0.41 2203495.0 84600.0 0.14 0.3859 0.8972 3630768 CBKinase1_020753 Cc1ccc(NC(=O)CSc2nnnn2C3CC4CCC3C4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B12 compound treatment 2045047.0 77900.0 0.13 2444982.0 326000.0 0.53 0.4711 0.8559 3630769 CBKinase1_020754 Cc1c(Cl)cccc1NC(=O)CSc2nnc(c3cccc(Cl)c3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B13 mock treatment 2001771.0 34600.0 0.06 1677199.0 -442000.0 -0.72 -0.4705 -0.6478 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B14 mock treatment 1985304.0 18100.0 0.03 1933204.0 -186000.0 -0.3 -0.1935 -0.6327 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B15 compound treatment 2109038.0 142000.0 0.24 2372867.0 254000.0 0.42 0.4641 0.9658 3630770 CBKinase1_020755 CCc1ccccc1NC(=O)CC(O)(C(=O)OC)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B16 compound treatment 1878790.0 -88400.0 -0.15 1846621.0 -272000.0 -0.45 -0.4214 -0.8952 1295141 CBKinase1_020756 Cn1c2ccccc2c3nnc(SCc4ccc5nonc5c4)nc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B17 compound treatment 1621827.0 -345000.0 -0.58 1689399.0 -430000.0 -0.7 -0.9111 -0.9957 3630771 CBKinase1_020757 CCn1ncc(Cl)c1C(=O)NCc2ccco2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B18 compound treatment 2171777.0 205000.0 0.35 2021981.0 -96900.0 -0.16 0.1325 0.3478 3630772 CBKinase1_020758 OC(=O)CCc1nn2c3ccccc3[nH]c2nc1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B19 compound treatment 2003789.0 36600.0 0.06 2256661.0 138000.0 0.23 0.2034 0.8691 3630773 CBKinase1_020759 Cn1nnnc1SCC(=O)Nc2ccc(cc2)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B20 compound treatment 1948022.0 -19200.0 -0.03 2046385.0 -72500.0 -0.12 -0.107 -0.8683 1984478 CBKinase1_020760 OC(=O)CCc1nn2c3ccccc3nc2n(c4ccccc4)c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B21 compound treatment 1661302.0 -306000.0 -0.52 1951696.0 -167000.0 -0.27 -0.5599 -0.9558 3630774 CBKinase1_020761 CC(=O)Nc1cccc(NC(=O)CSc2nnnn2C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B22 compound treatment 1817596.0 -150000.0 -0.25 1837850.0 -281000.0 -0.46 -0.5048 -0.9603 3630775 CBKinase1_020762 COc1ccc(cc1OC)C(=O)Cn2c3nc(nn3c4ccccc24)c5ccccc5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B23 compound treatment 2008040.0 40900.0 0.07 2166412.0 47500.0 0.08 0.1039 0.9983 3630776 CBKinase1_020763 OC(=O)c1ccc(Cl)cc1NC(=O)CSc2nnnn2c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 B24 compound treatment 1665207.0 -302000.0 -0.51 1471981.0 -647000.0 -1.06 -1.1112 -0.944 3630777 CBKinase1_020764 Cc1ccc(cc1)C(=O)NC(=O)CSc2nc(N)n[nH]2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C01 compound treatment 1631682.0 -336000.0 -0.57 1914758.0 -204000.0 -0.33 -0.6382 -0.9682 3630778 CBKinase1_020765 O=C1N(Cc2nc(no2)c3ccccn3)C(=O)c4ccccc14 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C02 compound treatment 1974087.0 6900.0 0.01 2098994.0 -19900.0 -0.03 -0.0148 -0.4277 3630779 CBKinase1_020766 Brc1cccc(c1)C2=NOC(C2)C(=O)Nc3cccnc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C03 compound treatment 2042560.0 75400.0 0.13 2223875.0 105000.0 0.17 0.2118 0.9892 3630780 CBKinase1_020767 [O-][N+](=O)c1ccccc1COC(=O)c2cccc(c2)c3nnc(o3)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C04 compound treatment 2196257.0 229000.0 0.39 2256123.0 137000.0 0.22 0.4332 0.9664 3630781 CBKinase1_020768 Cc1nn(Cc2ccc(F)cc2)c(C)c1NC(=O)C3CC(=NO3)c4cccc(Br)c4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C05 compound treatment 2086835.0 120000.0 0.2 2387790.0 269000.0 0.44 0.4548 0.9378 3630782 CBKinase1_020769 COc1cc(NC(=O)CN2C(=O)c3ccccc3C2=O)cc(OC)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C06 compound treatment 2035964.0 68800.0 0.12 2370022.0 251000.0 0.41 0.3733 0.8729 3630783 CBKinase1_020770 Oc1ccccc1C2=NOC(C2)C(=O)NCc3cccnc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C07 compound treatment 1699926.0 -267000.0 -0.45 1703094.0 -416000.0 -0.68 -0.8018 -0.9802 3630784 CBKinase1_020771 CN(CC(=O)Nc1nnc[nH]1)S(=O)(=O)c2cc(Cl)ccc2Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C08 compound treatment 1990347.0 23200.0 0.04 1962801.0 -156000.0 -0.26 -0.1532 -0.5918 3630785 CBKinase1_020772 O=C(NCc1cccnc1)c2cc(on2)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C09 compound treatment 2010148.0 43000.0 0.07 1876603.0 -242000.0 -0.4 -0.2294 -0.5682 3630786 CBKinase1_020773 OC(=O)CNC(=O)c1ccc(cc1)S(=O)(=O)N2CCCC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C10 compound treatment 1987154.0 20000.0 0.03 1985049.0 -134000.0 -0.22 -0.1312 -0.5912 3630787 CBKinase1_020774 Fc1ccc(cc1)C2=NC(c3c(N2)n(Cc4ccco4)c(=O)[nH]c3=O)(C(F)(F)F)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C11 mock treatment 1728442.0 -239000.0 -0.4 2053922.0 -65000.0 -0.11 -0.3611 -0.864 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C12 mock treatment 2126304.0 159000.0 0.27 2230345.0 111000.0 0.18 0.3196 0.9821 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C13 compound treatment 1479721.0 -487000.0 -0.83 1988860.0 -130000.0 -0.21 -0.7342 -0.8615 3630788 CBKinase1_020775 COC(=O)c1ccccc1NC(=O)CSc2[nH]c(=O)cc(C)c2C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C14 compound treatment 1786844.0 -180000.0 -0.31 2031077.0 -87800.0 -0.14 -0.3177 -0.9412 3630789 CBKinase1_020776 Fc1cccc(F)c1NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3cccs3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C15 mock treatment 2097388.0 130000.0 0.22 2219747.0 101000.0 0.17 0.2727 0.9899 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C16 mock treatment 1825136.0 -142000.0 -0.24 2109982.0 -8940.0 -0.01 -0.1804 -0.7488 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C17 compound treatment 1587406.0 -380000.0 -0.64 2061205.0 -57700.0 -0.09 -0.5215 -0.8025 1975288 CBKinase1_020777 Cc1cccc(NC(=O)CSc2nc(N)c(C#N)c(c2C#N)c3ccc(F)cc3)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C18 compound treatment 1393562.0 -574000.0 -0.97 1602946.0 -516000.0 -0.85 -1.2845 -0.9976 3630790 CBKinase1_020778 COc1ccc(NC(=O)CSc2nc3CCCCCc3cc2C#N)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C19 compound treatment 1532929.0 -434000.0 -0.74 1702602.0 -416000.0 -0.68 -1.0022 -0.9993 3630791 CBKinase1_020779 Cc1cc(nc(SCC(=O)Nc2ccc(I)cc2)c1C#N)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C20 compound treatment 1343589.0 -624000.0 -1.06 1250928.0 -868000.0 -1.42 -1.7523 -0.9892 3630792 CBKinase1_020780 FC(F)(F)c1cc(nc(SCc2ccccn2)c1C#N)c3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C21 compound treatment 2459593.0 492000.0 0.83 2705385.0 586000.0 0.96 1.269 0.9975 3630793 CBKinase1_020781 Clc1ccc(NC(=O)CSc2nc3CCCCCCc3cc2C#N)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C22 compound treatment 1463434.0 -504000.0 -0.85 1528958.0 -590000.0 -0.97 -1.2866 -0.998 1986064 CBKinase1_020782 Cc1cc(NC(=O)c2sc(NCC=C)nc2N)no1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C23 compound treatment 886193.0 -1080000.0 -1.83 1226808.0 -892000.0 -1.46 -2.3277 -0.9938 3630794 CBKinase1_020783 CN(C)S(=O)(=O)N1CCN(CC(=O)Nc2cc(Cl)ccc2Cl)CC1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 C24 compound treatment 1495430.0 -472000.0 -0.8 1686640.0 -432000.0 -0.71 -1.0656 -0.9982 3630795 CBKinase1_020784 CCc1nc(SCC(=O)Nc2c(Cl)cccc2Cl)c(C#N)c(c1C)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D01 compound treatment 1505611.0 -462000.0 -0.78 1709870.0 -409000.0 -0.67 -1.0265 -0.9971 3630796 CBKinase1_020785 COc1cc(CNC2CCCC2)cc(I)c1OCC(=O)N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D02 compound treatment 1834051.0 -133000.0 -0.23 2075277.0 -43600.0 -0.07 -0.2099 -0.8879 3630797 CBKinase1_020786 CSc1nc(C)cc(SCC(=O)Nc2ccccc2)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D03 compound treatment 1967046.0 -139.0 0.0 2102071.0 -16900.0 -0.03 -0.0197 -0.7131 3630798 CBKinase1_020787 COc1cc(Cl)cc(C#N)c1OCC(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D04 compound treatment 2016174.0 49000.0 0.08 2183282.0 64400.0 0.11 0.1332 0.9929 3630799 CBKinase1_020788 Cc1ccc(cc1)N2CC(CC2=O)C(=O)NCc3cccnc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D05 compound treatment 2225003.0 258000.0 0.44 2426185.0 307000.0 0.5 0.6647 0.9975 1084883 CBKinase1_020789 OC(=O)c1ccccc1OCC(=O)Nc2ccccc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D06 compound treatment 2181459.0 214000.0 0.36 2318471.0 200000.0 0.33 0.4877 0.9987 3630800 CBKinase1_020790 COCCSc1nnc(NC(=O)c2sc3ccccc3c2Cl)s1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D07 compound treatment 2100188.0 133000.0 0.23 2252897.0 134000.0 0.22 0.3145 0.9999 3630801 CBKinase1_020791 CC(=O)c1ccc(NC(=O)CSc2nnc(c3cccs3)n2c4ccccc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D08 compound treatment 2072546.0 105000.0 0.18 2356983.0 238000.0 0.39 0.402 0.9371 3630802 CBKinase1_020792 Cc1ccccc1c2nnc(SCC(=O)Nc3ccc4OCCOc4c3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D09 compound treatment 2004037.0 36900.0 0.06 2253039.0 134000.0 0.22 0.1995 0.8733 3630803 CBKinase1_020793 Cc1cc(O)nc(SCC(=O)Nc2cc(ccc2C)[N+](=O)[O-])n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D10 compound treatment 1847026.0 -120000.0 -0.2 2328642.0 210000.0 0.34 0.0992 0.2484 3630804 CBKinase1_020794 Clc1ccccc1c2nnc(SCC(=O)Nc3ccc(Br)cc3)n2c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D11 mock treatment 1745187.0 -222000.0 -0.38 2220669.0 102000.0 0.17 -0.1478 -0.3595 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D12 mock treatment 2074248.0 107000.0 0.18 2296249.0 177000.0 0.29 0.3336 0.9742 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D13 compound treatment 1853901.0 -113000.0 -0.19 2209140.0 90200.0 0.15 -0.031 -0.1282 3630805 CBKinase1_020795 CN1C(=O)C(CC(=O)Nc2ccc(Cl)cc2)N(Cc3ccco3)C1=S 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D14 compound treatment 1403928.0 -563000.0 -0.95 1821477.0 -297000.0 -0.49 -1.0189 -0.9515 3630806 CBKinase1_020796 CCC(Sc1nncn1C)C(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D15 mock treatment 1910128.0 -57100.0 -0.1 2094653.0 -24300.0 -0.04 -0.0964 -0.9231 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D16 mock treatment 2250069.0 283000.0 0.48 2017455.0 -101000.0 -0.17 0.221 0.436 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D17 compound treatment 1643398.0 -324000.0 -0.55 1986402.0 -133000.0 -0.22 -0.5411 -0.9179 3630807 CBKinase1_020797 [O-][N+](=O)c1nn(CC(=O)Nc2ccccc2F)cc1Br 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D18 compound treatment 1770763.0 -196000.0 -0.33 2206282.0 87400.0 0.14 -0.1339 -0.3698 1669215 CBKinase1_020798 Cn1c2ccccc2n3nc(CCC(=O)O)c(=O)nc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D19 compound treatment 1617870.0 -349000.0 -0.59 1681383.0 -438000.0 -0.72 -0.9252 -0.9954 3630808 CBKinase1_020799 Cn1nnnc1SCC(=O)Nc2ccc(F)c(F)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D20 compound treatment 1881684.0 -85500.0 -0.14 1957899.0 -161000.0 -0.26 -0.2889 -0.96 3630809 CBKinase1_020800 OC(=O)CCc1nn2c3ccccc3nc2n(Cc4ccccc4)c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D21 compound treatment 1622337.0 -345000.0 -0.58 1899832.0 -219000.0 -0.36 -0.6667 -0.9728 3630810 CBKinase1_020801 Cn1nnnc1SCC(=O)Nc2ncccn2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D22 compound treatment 1724444.0 -243000.0 -0.41 2171432.0 52500.0 0.09 -0.2297 -0.5471 3630811 CBKinase1_020802 O=C(Cn1c2nc(nn2c3ccccc13)c4ccccc4)c5cccs5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D23 compound treatment 1238954.0 -728000.0 -1.23 1233710.0 -885000.0 -1.45 -1.8975 -0.9967 3630812 CBKinase1_020803 COc1ccc(NC(=O)CSc2nc3CCN(C)Cc3c(c4cccs4)c2C#N)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 D24 compound treatment 1597385.0 -370000.0 -0.63 1668718.0 -450000.0 -0.74 -0.9644 -0.9967 3630813 CBKinase1_020804 Cc1ccc(cc1)C(=O)NC(=O)CSc2nnnn2c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E01 mock treatment 1815165.0 -152000.0 -0.26 2181907.0 63000.0 0.1 -0.109 -0.393 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E02 mock treatment 1993412.0 26200.0 0.04 2294036.0 175000.0 0.29 0.2343 0.8069 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E03 compound treatment 2211550.0 244000.0 0.41 2283914.0 165000.0 0.27 0.4837 0.9788 3630814 CBKinase1_020805 Clc1cccc(NC(=O)c2ccccc2OCC(=O)Nc3ccc(N4CCOCC4)c(Cl)c3)c1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E04 compound treatment 2156260.0 189000.0 0.32 2168239.0 49300.0 0.08 0.2835 0.8587 3630815 CBKinase1_020806 Clc1ccc(Cn2cc(NC(=O)C3CC(=NO3)c4cccc(Br)c4)cn2)c(Cl)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E05 compound treatment 2369921.0 403000.0 0.68 2375654.0 257000.0 0.42 0.7796 0.9731 3630816 CBKinase1_020807 CC(NC(=O)c1ccc(Cl)cc1)C(=O)NC(C)(C)CO 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E06 compound treatment 2301926.0 335000.0 0.57 2314817.0 196000.0 0.32 0.6277 0.9638 3630817 CBKinase1_020808 Oc1ccccc1C2=NOC(C2)C(=O)NCc3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E07 compound treatment 2441147.0 474000.0 0.8 2364060.0 245000.0 0.4 0.8514 0.9489 1292553 CBKinase1_020809 Brc1ccccc1NC(=O)Cn2cnc3ccccc3c2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E08 compound treatment 1243081.0 -724000.0 -1.23 1384674.0 -734000.0 -1.2 -1.7176 -1.0 3630818 CBKinase1_020810 O=C(NCc1ccco1)c2cc(on2)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E09 mock treatment 2183074.0 216000.0 0.37 2420687.0 302000.0 0.49 0.6081 0.9889 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E10 mock treatment 2289295.0 322000.0 0.55 2511472.0 393000.0 0.64 0.8405 0.9966 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E11 compound treatment 2170766.0 204000.0 0.34 2515014.0 396000.0 0.65 0.7027 0.9561 3630819 CBKinase1_020811 CN(CC(=O)N1CCN(CC1)c2ccccn2)S(=O)(=O)c3ccc4ccccc4c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E12 compound treatment 2392881.0 426000.0 0.72 3306826.0 1190000.0 1.95 1.8861 0.9086 3630820 CBKinase1_020812 COC(=O)C(NC(=O)c1ccccc1)(c2c(C)[nH]n(c3ccccc3)c2=O)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E13 compound treatment 2233914.0 267000.0 0.45 2466504.0 348000.0 0.57 0.7221 0.9934 3630821 CBKinase1_020813 COC(=O)c1cc(OC)c(OC)cc1NC(=O)CSc2nc(C)cc(c2C#N)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E14 compound treatment 2065157.0 98000.0 0.17 2302695.0 184000.0 0.3 0.3302 0.9605 3630822 CBKinase1_020814 Cc1cc(c2cccs2)c(C#N)c(SCC(=O)Nc3cccc(F)c3)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E15 compound treatment 1513198.0 -454000.0 -0.77 1934515.0 -184000.0 -0.3 -0.7571 -0.9168 3630823 CBKinase1_020815 Nc1nc(SCCN2CCOCC2)c(C#N)cc1C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E16 compound treatment 2087252.0 120000.0 0.2 2497688.0 379000.0 0.62 0.5826 0.892 3630824 CBKinase1_020816 COc1cccc(c1)c2ccc(C#N)c(SCC(=O)Nc3ccccc3Br)n2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E17 mock treatment 2248860.0 282000.0 0.48 2534098.0 415000.0 0.68 0.8183 0.9849 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E18 mock treatment 2467642.0 500000.0 0.85 2636984.0 518000.0 0.85 1.1994 1.0 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E19 compound treatment 1966148.0 -1040.0 0.0 2431038.0 312000.0 0.51 0.3605 0.7047 3630825 CBKinase1_020817 COc1ccc(NC(=O)CSc2[nH]c(=O)cc(C)c2C#N)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E20 compound treatment 416094.0 -1550000.0 -2.63 1297163.0 -822000.0 -1.35 -2.8089 -0.9519 3630826 CBKinase1_020818 CC(C)(C)c1cc(c(C#N)c(SCC(=O)Nc2cccc(F)c2)n1)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E21 compound treatment 1160572.0 -807000.0 -1.37 1734599.0 -384000.0 -0.63 -1.4108 -0.9383 3630827 CBKinase1_020819 COc1ccc(cc1)c2cc(nc(SC(C(=O)O)c3ccccc3)c2C#N)c4cccs4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E22 compound treatment 1511542.0 -456000.0 -0.77 1611273.0 -508000.0 -0.83 -1.1337 -0.9993 3630828 CBKinase1_020820 COc1ccc(NC(=O)CSc2nc3CCCc3c(c2C#N)C(F)(F)F)c(OC)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E23 compound treatment 1679271.0 -288000.0 -0.49 1677327.0 -442000.0 -0.72 -0.8564 -0.9815 3630829 CBKinase1_020821 COc1ccc(NC(=O)CN2CCN(CC2)S(=O)(=O)c3ccc(F)cc3)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 E24 compound treatment 1711346.0 -256000.0 -0.43 1618295.0 -501000.0 -0.82 -0.8864 -0.9554 3630830 CBKinase1_020822 CCC1CCc2nc(SCC(=O)Nc3cccc(OC)c3)c(C#N)c(c2C1)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F01 mock treatment 1637106.0 -330000.0 -0.56 1578273.0 -541000.0 -0.89 -1.0216 -0.9753 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F02 mock treatment 1852481.0 -115000.0 -0.19 2061006.0 -57900.0 -0.09 -0.2044 -0.9458 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F03 compound treatment 2040009.0 72800.0 0.12 2197931.0 79000.0 0.13 0.1787 0.9997 3630831 CBKinase1_020823 COc1ccccc1NC(=O)COc2ccc(cc2OC)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F04 compound treatment 2062225.0 95000.0 0.16 2213663.0 94700.0 0.16 0.2235 0.9998 3630832 CBKinase1_020824 Cc1ccc(cc1)N2CC(CC2=O)C(=O)Nc3ccc(cc3)S(=O)(=O)NCC4CCCO4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F05 compound treatment 2048629.0 81400.0 0.14 2155594.0 36700.0 0.06 0.14 0.9308 3630833 CBKinase1_020825 CCOc1c(OC)cc(Cl)cc1C2NC(=O)NC(=C2C(=O)Nc3ccccc3C(=O)OC)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F06 compound treatment 2188799.0 222000.0 0.38 2403180.0 284000.0 0.47 0.5947 0.9942 3630834 CBKinase1_020826 O=C(Nc1ccc(cc1)S(=O)(=O)NCC2CCCO2)C3CCCO3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F07 compound treatment 2350845.0 384000.0 0.65 2205873.0 86900.0 0.14 0.56 0.8422 3630835 CBKinase1_020827 CCc1nnc(SCC(=O)Nc2ccnc3ccccc23)[nH]1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F08 compound treatment 2224789.0 258000.0 0.44 2350935.0 232000.0 0.38 0.5772 0.9977 3630836 CBKinase1_020828 Cc1ccccc1c2nnc(SCC(=O)Nc3ccc(cc3)S(=O)(=O)N)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F09 mock treatment 2490941.0 524000.0 0.89 2614228.0 495000.0 0.81 1.2009 0.999 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F10 mock treatment 2280808.0 314000.0 0.53 2551601.0 433000.0 0.71 0.8768 0.9898 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F11 compound treatment 2493601.0 526000.0 0.89 2578887.0 460000.0 0.75 1.1631 0.9965 3630837 CBKinase1_020829 Cn1c(=O)n(C)c2nc(NCc3cccnc3)n(Cc4ccc(Cl)cc4Cl)c2c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F12 compound treatment 2213781.0 247000.0 0.42 2529288.0 410000.0 0.67 0.7707 0.9737 3630838 CBKinase1_020830 COc1ccc(NC(=O)CSc2nnc(c3cccc(Cl)c3)n2C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F13 compound treatment 2133188.0 166000.0 0.28 2603148.0 484000.0 0.79 0.7598 0.9026 1849884 CBKinase1_020831 COc1ccc(NC(=O)CSc2nc(c(o2)c3ccccc3)c4ccccc4)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F14 compound treatment 1992408.0 25200.0 0.04 2551526.0 433000.0 0.71 0.5315 0.7483 3630839 CBKinase1_020832 CCOC(=O)CSc1ncc(nn1)c2ccccc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F15 compound treatment 1960590.0 -6590.0 -0.01 2572929.0 454000.0 0.74 0.5182 0.6964 3630840 CBKinase1_020833 COC(=O)C(O)(CC(=O)Nc1cccc(SC)c1)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F16 compound treatment 2006629.0 39400.0 0.07 2608096.0 489000.0 0.8 0.6141 0.7634 3630841 CBKinase1_020834 COC(=O)CCCCC(=O)c1[nH]c(=O)[nH]c1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F17 mock treatment 2077376.0 110000.0 0.19 2579019.0 460000.0 0.75 0.6651 0.8562 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F18 mock treatment 2125707.0 159000.0 0.27 2314777.0 196000.0 0.32 0.4167 0.996 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F19 compound treatment 2073018.0 106000.0 0.18 2444334.0 325000.0 0.53 0.5038 0.8955 3630842 CBKinase1_020835 Cn1nnnc1SCC(=O)Nc2ccc3ccccc3c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F20 compound treatment 2343983.0 377000.0 0.64 2450225.0 331000.0 0.54 0.8349 0.9968 3630843 CBKinase1_020836 OC(=O)CCc1nn2c3ccccc3n(CC=C)c2nc1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F21 compound treatment 2323923.0 357000.0 0.6 2436189.0 317000.0 0.52 0.7947 0.9972 3630844 CBKinase1_020837 CCOC(=O)NC(=O)CSc1nnnn1c2ccccc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F22 compound treatment 1501373.0 -466000.0 -0.79 1731686.0 -387000.0 -0.63 -1.0063 -0.9942 3630845 CBKinase1_020838 CCOC(=O)c1c(CN2CCOCC2)nc3c4ccccc4ccn13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F23 compound treatment 1290588.0 -677000.0 -1.15 1940821.0 -178000.0 -0.29 -1.0162 -0.8598 3630846 CBKinase1_020839 CN1CCc2nc(SCC(=O)Nc3ccc(cc3)C(C)(C)C)c(C#N)cc2C1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 F24 compound treatment 1639197.0 -328000.0 -0.56 2188529.0 69600.0 0.11 -0.3119 -0.5503 3630847 CBKinase1_020840 Cc1nnc(SCC(=O)NC(=O)c2ccc(C)cc2)s1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G01 compound treatment 1612239.0 -355000.0 -0.6 2007592.0 -111000.0 -0.18 -0.5539 -0.8821 3630848 CBKinase1_020841 [O-][N+](=O)c1cccc(c1)S(=O)(=O)Nc2cccc(NC(=O)c3cccs3)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G02 compound treatment 2160085.0 193000.0 0.33 2099816.0 -19100.0 -0.03 0.2087 0.6364 3630849 CBKinase1_020842 Cc1cc(NC(=O)C2CC(=NO2)c3cccc(Br)c3)n(n1)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G03 mock treatment 2011720.0 44500.0 0.08 2124257.0 5330.0 0.01 0.0595 0.7838 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G04 mock treatment 1954433.0 -12800.0 -0.02 2102645.0 -16300.0 -0.03 -0.0341 -0.9945 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G05 compound treatment 2152810.0 186000.0 0.31 2492602.0 374000.0 0.61 0.6552 0.9519 3630850 CBKinase1_020843 COc1ccc(cc1[N+](=O)[O-])C(=O)N(Cc2nc(no2)c3ccc(Cl)cc3)C(C)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G06 compound treatment 2386238.0 419000.0 0.71 2329181.0 210000.0 0.34 0.7452 0.945 3630851 CBKinase1_020844 Oc1ccccc1C2=NOC(C2)C(=O)NCC3CCCO3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G07 compound treatment 2230367.0 263000.0 0.45 2400579.0 282000.0 0.46 0.6414 0.9998 3630852 CBKinase1_020845 COC(=O)c1ccccc1NC(=O)CSc2nc(cs2)c3ccc(F)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G08 compound treatment 2084225.0 117000.0 0.2 2055170.0 -63800.0 -0.1 0.0662 0.2956 3630853 CBKinase1_020846 O=C(NCCCN1CCOCC1)c2cc(on2)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G09 compound treatment 2163163.0 196000.0 0.33 2626263.0 507000.0 0.83 0.8225 0.9188 3630854 CBKinase1_020847 Cc1cc(O)nc(SCCOc2ccc3CCCc3c2)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G10 compound treatment 2054861.0 87700.0 0.15 2519328.0 400000.0 0.66 0.569 0.8457 3630855 CBKinase1_020848 Cc1ccc(cc1)C(=O)NC2(C(=O)N(Cc3ccccn3)C4=C2C(=O)CC(C)(C)C4)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G11 compound treatment 2366773.0 400000.0 0.68 2584661.0 466000.0 0.76 1.018 0.9982 3630856 CBKinase1_020849 OC(=O)CNC(=O)c1ccc(cc1)S(=O)(=O)N2CCOCC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G12 compound treatment 2101868.0 135000.0 0.23 2453687.0 335000.0 0.55 0.5492 0.9243 3630857 CBKinase1_020850 O=C(Nc1ccc(cc1)C(=O)NCCN2CCOCC2)C3COc4ccccc4O3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G13 compound treatment 2293822.0 327000.0 0.55 2558264.0 439000.0 0.72 0.9001 0.9915 3630858 CBKinase1_020851 COC(=O)Cc1[nH]nc2OC(=C(C#N)C3(CCSCC3)c12)N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G14 compound treatment 2468419.0 501000.0 0.85 2518085.0 399000.0 0.65 1.0625 0.9917 3630859 CBKinase1_020852 CCOC(=O)c1sc(NC(=O)CSc2ccccn2)c(C#N)c1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G15 compound treatment 2058996.0 91800.0 0.16 2380504.0 262000.0 0.43 0.413 0.9058 1216030 CBKinase1_020853 COc1ccc(NC(=O)CSc2nc3CCCCc3c(c4cccs4)c2C#N)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G16 compound treatment 2735270.0 768000.0 1.3 2827234.0 708000.0 1.16 1.7402 0.9984 3630860 CBKinase1_020854 FC(F)(F)Oc1ccccc1NC(=O)CSc2nc3CCCCc3cc2C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G17 compound treatment 2069715.0 103000.0 0.17 2392541.0 274000.0 0.45 0.4398 0.9147 3630861 CBKinase1_020855 COc1ccc(cc1CSc2ccccn2)C3C(=C(N)Oc4n[nH]c(c34)c5ccccc5)C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G18 compound treatment 2155425.0 188000.0 0.32 2546156.0 427000.0 0.7 0.7204 0.9365 3630862 CBKinase1_020856 CC(C)OC(=O)CSc1nc2CCCCCc2cc1C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G19 mock treatment 2294845.0 328000.0 0.55 2533278.0 414000.0 0.68 0.8724 0.995 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G20 mock treatment 2144869.0 178000.0 0.3 2438813.0 320000.0 0.52 0.5834 0.9652 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G21 compound treatment 2251342.0 284000.0 0.48 2251823.0 133000.0 0.22 0.4941 0.9358 3630863 CBKinase1_020857 COc1ccc(NC(=O)CSc2nc(cc(c3ccsc3)c2C#N)c4cccs4)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G22 compound treatment 1483677.0 -484000.0 -0.82 1586888.0 -532000.0 -0.87 -1.1953 -0.9995 3630864 CBKinase1_020858 Fc1ccc(NC(=O)CSc2nc3CCCCCc3c(c2C#N)C(F)(F)F)c(Cl)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G23 compound treatment 1117504.0 -850000.0 -1.44 1220332.0 -899000.0 -1.47 -2.0584 -0.9999 3630865 CBKinase1_020859 Brc1ccc(NC(=O)CN2CCN(CC2)S(=O)(=O)c3ccc4ccccc4c3)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 G24 compound treatment 1463160.0 -504000.0 -0.85 1707573.0 -411000.0 -0.67 -1.08 -0.9932 3630866 CBKinase1_020860 COC(=O)c1ccccc1NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3cccs3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H01 compound treatment 1495708.0 -471000.0 -0.8 1789769.0 -329000.0 -0.54 -0.9458 -0.9818 3630867 CBKinase1_020861 COc1cc(ccc1OCC#N)C2NC(=S)NC(=C2C(=O)Nc3ccccc3Cl)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H02 compound treatment 1935952.0 -31200.0 -0.05 2346465.0 228000.0 0.37 0.2263 0.6009 3630868 CBKinase1_020862 CSc1nc(C)cc(OCC(=O)Nc2ccc(Cl)cc2)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H03 mock treatment 2008925.0 41700.0 0.07 2140803.0 21900.0 0.04 0.0753 0.9506 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H04 mock treatment 2186822.0 220000.0 0.37 2281812.0 163000.0 0.27 0.4517 0.9868 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H05 compound treatment 2150918.0 184000.0 0.31 2304911.0 186000.0 0.3 0.4354 0.9999 3630869 CBKinase1_020863 COc1cc(cc(I)c1OCC(=O)O)C2NC(=O)NC(=C2C(=O)c3ccccc3)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H06 compound treatment 2219064.0 252000.0 0.43 2165095.0 46200.0 0.08 0.355 0.8198 3630870 CBKinase1_020864 COc1cccc(c1)c2nnc(SCC(=O)N)n2c3ccc(Cl)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H07 compound treatment 1681246.0 -286000.0 -0.48 2060750.0 -58200.0 -0.1 -0.4097 -0.8304 3630871 CBKinase1_020865 O=C(CSc1nnc(c2ccco2)n1c3ccccc3)Nc4ccnc5ccccc45 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H08 compound treatment 2020721.0 53500.0 0.09 2020252.0 -98700.0 -0.16 -0.0503 -0.2712 3630872 CBKinase1_020866 Cn1c(SCC(=O)Nc2ccc(F)c(Cl)c2)nnc1c3ccccc3Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H09 compound treatment 2205276.0 238000.0 0.4 2316277.0 197000.0 0.32 0.5137 0.9941 3630873 CBKinase1_020867 Cc1nc(SCC(=O)Nc2ccc(cc2)C(=O)O)nc(O)c1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H10 compound treatment 2022053.0 54900.0 0.09 2590166.0 471000.0 0.77 0.6118 0.7865 3630874 CBKinase1_020868 Clc1ccccc1c2nnc(SCc3nc4ccccc4[nH]3)n2c5ccccc5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H11 compound treatment 2075531.0 108000.0 0.18 2550112.0 431000.0 0.71 0.6294 0.8621 3630875 CBKinase1_020869 Cc1cccc(Cn2c(NCCCO)nc3n(C)c(=O)n(C)c(=O)c23)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H12 compound treatment 2137145.0 170000.0 0.29 2365764.0 247000.0 0.4 0.4895 0.9861 3630876 CBKinase1_020870 COC(=O)c1ccc(NC(=O)CSc2nnc(c3cccc(Cl)c3)n2C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H13 compound treatment 2040808.0 73600.0 0.12 2363811.0 245000.0 0.4 0.3719 0.885 3630877 CBKinase1_020871 CC(=O)c1cccc(NC(=O)CSc2nc(c(o2)c3ccccc3)c4ccccc4)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H14 compound treatment 2170258.0 203000.0 0.34 2404699.0 286000.0 0.47 0.5742 0.9884 3630878 CBKinase1_020872 Brc1ccc(cc1)C(=O)CSc2ncc(nn2)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H15 compound treatment 1795176.0 -172000.0 -0.29 2394650.0 276000.0 0.45 0.1136 0.2114 3630879 CBKinase1_020873 COc1ccc(cc1NC(=O)CC(O)(C(F)(F)F)C(F)(F)F)C(=O)N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H16 compound treatment 1889679.0 -77500.0 -0.13 2596440.0 478000.0 0.78 0.4606 0.5805 1292361 CBKinase1_020874 C(Cn1c2ccccc2c3nnc(SCc4ccc5nonc5c4)nc13)c6ccccc6 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H17 compound treatment 2184896.0 218000.0 0.37 2333464.0 215000.0 0.35 0.5092 0.9997 1303088 CBKinase1_020875 Cn1nnnc1SCC(=O)Nc2ccc(C#N)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H18 compound treatment 2148979.0 182000.0 0.31 2310737.0 192000.0 0.31 0.4399 0.9999 1261623 CBKinase1_020876 OC(=O)CCc1nn2c3ccccc3n(Cc4ccccc4)c2nc1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H19 mock treatment 2069374.0 102000.0 0.17 2333128.0 214000.0 0.35 0.3705 0.9468 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H20 mock treatment 2013920.0 46700.0 0.08 2413348.0 294000.0 0.48 0.3971 0.8122 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H21 compound treatment 1915032.0 -52200.0 -0.09 2201737.0 82800.0 0.14 0.0335 0.2072 3630880 CBKinase1_020877 CCOC(=O)NC(=O)CSc1nc2ccccc2s1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H22 compound treatment 2299891.0 333000.0 0.56 2332267.0 213000.0 0.35 0.6455 0.9737 3630881 CBKinase1_020878 CCOC(=O)c1c(CSc2nc(C)cc(C)n2)nc3c4ccccc4ccn13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H23 compound treatment 925947.0 -1040000.0 -1.76 969282.0 -1150000.0 -1.88 -2.5786 -0.9994 3630882 CBKinase1_020879 Cc1cc(c(C#N)c(SCC(=O)Nc2ccc(Cl)cc2)n1)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 H24 compound treatment 2229053.0 262000.0 0.44 2094960.0 -24000.0 -0.04 0.2857 0.6419 3630883 CBKinase1_020880 COc1ccccc1NC(=O)CSc2ncc(nn2)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I01 compound treatment 1810158.0 -157000.0 -0.27 1781341.0 -338000.0 -0.55 -0.5792 -0.9436 3630884 CBKinase1_020881 Cc1cc(O)nc(SCCOc2cccc(Oc3ccccc3)c2)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I02 compound treatment 1952664.0 -14500.0 -0.02 1823447.0 -295000.0 -0.48 -0.3598 -0.742 3630885 CBKinase1_020882 Brc1cccc(c1)C2=NOC(C2)C(=O)NCc3cccnc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I03 compound treatment 2108687.0 142000.0 0.24 2067969.0 -51000.0 -0.08 0.1103 0.4349 3630886 CBKinase1_020883 Cc1ccc(O)c(NC(=O)CCCC(=O)O)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I04 compound treatment 2516127.0 549000.0 0.93 2263430.0 145000.0 0.24 0.8245 0.8598 3630887 CBKinase1_020884 CCOC(=O)c1c(C)c(sc1NC(=O)C2CC(=NO2)c3cccc(Br)c3)C(=O)OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I05 mock treatment 2320076.0 353000.0 0.6 2215448.0 96500.0 0.16 0.5342 0.8646 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I06 mock treatment 2172788.0 206000.0 0.35 2491657.0 373000.0 0.61 0.678 0.9644 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I07 compound treatment 1424461.0 -543000.0 -0.92 1363979.0 -755000.0 -1.24 -1.5245 -0.9893 3630888 CBKinase1_020885 CCOc1ccc(cc1)C(Nc2ccccn2)c3cc(Cl)c4cccnc4c3O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I08 compound treatment 2142235.0 175000.0 0.3 2281310.0 162000.0 0.27 0.3977 0.9986 3124174 CBKinase1_020886 O=C(NCCCn1ccnc1)c2cc(on2)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I09 compound treatment 2256980.0 290000.0 0.49 2810924.0 692000.0 1.13 1.1488 0.9297 3630889 CBKinase1_020887 CC(Oc1ccc(cc1)C(C)(C)C)C(=O)NCc2ccccn2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I10 compound treatment 2358750.0 392000.0 0.66 2322868.0 204000.0 0.33 0.705 0.9498 3630890 CBKinase1_020888 CC1(C)CC2=C(C(=O)C1)C(NC(=O)c3ccco3)(C(=O)N2Cc4ccco4)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I11 compound treatment 2034685.0 67500.0 0.11 1837023.0 -282000.0 -0.46 -0.2459 -0.5167 3630891 CBKinase1_020889 Cc1cc(ccc1NC(=O)CNC(=O)C2CCCCC2)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I12 compound treatment 2225759.0 259000.0 0.44 2310930.0 192000.0 0.31 0.532 0.9869 3630892 CBKinase1_020890 O=C(NCCN1CCOCC1)C(=O)NCC2COc3ccccc3O2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I13 compound treatment 2399548.0 432000.0 0.73 2198605.0 79700.0 0.13 0.6098 0.8203 1971439 CBKinase1_020891 CCc1nc(SCC(=O)Nc2cccc(c2)C(F)(F)F)c(C#N)cc1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I14 compound treatment 2173679.0 206000.0 0.35 2572589.0 454000.0 0.74 0.7729 0.9408 3630893 CBKinase1_020892 Cc1cc(C)c(C#N)c(SCC(=O)Nc2sc3CCCc3c2C#N)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I15 compound treatment 2294883.0 328000.0 0.55 2218486.0 99600.0 0.16 0.5076 0.8779 3630894 CBKinase1_020893 CSc1nc(N)nc(SCC(=O)Nc2cccc(F)c2)c1C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I16 compound treatment 2290400.0 323000.0 0.55 2485547.0 367000.0 0.6 0.8117 0.9989 3630895 CBKinase1_020894 Fc1cccc(NC(=O)CSc2nc3CCCCCc3cc2C#N)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I17 compound treatment 2290272.0 323000.0 0.55 2459993.0 341000.0 0.56 0.782 0.9999 1451182 CBKinase1_020895 Cc1ccc(cc1)C(=O)CSc2nsc3sc(C(=O)c4ccc(C)cc4)c(N)c23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I18 compound treatment 2327388.0 360000.0 0.61 2257274.0 138000.0 0.23 0.5915 0.9092 1848194 CBKinase1_020896 Cc1cccc(C)c1NC(=O)CSc2nc3CCCc3cc2C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I19 compound treatment 2257950.0 291000.0 0.49 2177488.0 58600.0 0.1 0.4159 0.8294 3630896 CBKinase1_020897 CSc1nc(N)nc(SCCS(=O)(=O)c2ccc(Cl)cc2)c1C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I20 compound treatment 1726544.0 -241000.0 -0.41 2306524.0 188000.0 0.31 -0.0706 -0.1384 3630897 CBKinase1_020898 COc1ccc(cc1OC)c2cc(c(C#N)c(SCC(=O)c3ccc(O)c(O)c3)n2)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I21 mock treatment 2068582.0 101000.0 0.17 2248515.0 130000.0 0.21 0.2715 0.9944 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I22 mock treatment 2144591.0 177000.0 0.3 2247342.0 128000.0 0.21 0.3612 0.9849 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I23 compound treatment 2037306.0 70100.0 0.12 2380078.0 261000.0 0.43 0.3866 0.8704 3630898 CBKinase1_020899 COc1ccc(NC(=O)CN2CCN(CC2)S(=O)(=O)c3ccc4ccccc4c3)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 I24 compound treatment 2217413.0 250000.0 0.42 1859372.0 -260000.0 -0.43 -0.0013 -0.0021 3630899 CBKinase1_020900 COc1cc(OC)cc(c1)C2C(=C(N)Oc3n[nH]c(c23)c4cccnc4)C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J01 compound treatment 1324616.0 -643000.0 -1.09 1549285.0 -570000.0 -0.93 -1.4292 -0.9971 3630900 CBKinase1_020901 COc1cc(C2NC(=S)NC(=C2C(=O)Nc3ccccc3C)C)c(Br)cc1OCC(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J02 compound treatment 1675753.0 -291000.0 -0.49 1740720.0 -378000.0 -0.62 -0.7871 -0.9936 3630901 CBKinase1_020902 N#CCCSc1nnc(c2cccnc2)n1Cc3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J03 compound treatment 1627206.0 -340000.0 -0.58 1581036.0 -538000.0 -0.88 -1.0303 -0.9786 3630902 CBKinase1_020903 CC(C)NCc1ccccc1OCC(=O)N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J04 compound treatment 1863851.0 -103000.0 -0.17 1972464.0 -146000.0 -0.24 -0.2934 -0.9879 3630903 CBKinase1_020904 CS(=O)(=O)Nc1ccc(cc1)S(=O)(=O)NCC2CCCO2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J05 mock treatment 1910568.0 -56600.0 -0.1 2054011.0 -64900.0 -0.11 -0.143 -0.9986 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J06 mock treatment 1940472.0 -26700.0 -0.05 2350147.0 231000.0 0.38 0.236 0.6183 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J07 compound treatment 2008512.0 41300.0 0.07 1932618.0 -186000.0 -0.31 -0.1664 -0.5313 1984431 CBKinase1_020905 O=c1nc(NCc2ccco2)sc3ncccc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J08 compound treatment 1584608.0 -383000.0 -0.65 1761119.0 -358000.0 -0.59 -0.8726 -0.9988 3630904 CBKinase1_020906 Cn1c(SCC(=O)Nc2cccc(Br)c2)nnc1c3ccccc3Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J09 compound treatment 2156363.0 189000.0 0.32 1851588.0 -267000.0 -0.44 -0.0834 -0.1536 3630905 CBKinase1_020907 Cc1ccc(cc1NC(=O)CSC2=NCCS2)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J10 compound treatment 1887335.0 -79800.0 -0.14 2030404.0 -88500.0 -0.15 -0.1982 -0.9994 3630906 CBKinase1_020908 NS(=O)(=O)c1ccc(NC(=O)CSc2nnc(c3ccccc3Cl)n2c4ccccc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J11 compound treatment 1988874.0 21700.0 0.04 2140581.0 21700.0 0.04 0.0511 0.9999 3630907 CBKinase1_020909 COCCNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccc(Cl)cc3Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J12 compound treatment 2043580.0 76400.0 0.13 1918680.0 -200000.0 -0.33 -0.1406 -0.3986 3630908 CBKinase1_020910 CCn1c(SCC(=O)Nc2ccc3OCCOc3c2)nnc1c4cccc(Cl)c4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J13 compound treatment 1788554.0 -179000.0 -0.3 2212290.0 93400.0 0.15 -0.1056 -0.3116 3630909 CBKinase1_020911 COC(=O)C(O)(CC(=O)Nc1ccc(C)c(F)c1)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J14 compound treatment 1856947.0 -110000.0 -0.19 2038011.0 -80900.0 -0.13 -0.2257 -0.986 3630910 CBKinase1_020912 CCOC(=O)C(C)Sc1nnc2c3ccccc3n(C)c2n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J15 compound treatment 1977835.0 10700.0 0.02 2069395.0 -49500.0 -0.08 -0.0447 -0.537 3630911 CBKinase1_020913 COC(=O)c1ccccc1NC(=O)CC(O)(C(F)(F)F)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J16 compound treatment 1915002.0 -52200.0 -0.09 2036392.0 -82500.0 -0.14 -0.1581 -0.9787 3630912 CBKinase1_020914 O=C(OCc1ccc2nonc2c1)c3cc(nc4ccccc34)c5ccccc5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J17 compound treatment 2061048.0 93900.0 0.16 1753317.0 -366000.0 -0.6 -0.3113 -0.5023 1343044 CBKinase1_020915 COc1cccc(NC(=O)CSc2nnnn2C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J18 compound treatment 1968674.0 1490.0 0.0 2172884.0 54000.0 0.09 0.0643 0.727 1215330 CBKinase1_020916 OC(=O)CCc1nn2c3ccccc3n(CC(=O)c4ccccc4)c2nc1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J19 compound treatment 2079060.0 112000.0 0.19 2309618.0 191000.0 0.31 0.3549 0.9712 3630913 CBKinase1_020917 Cn1nnnc1SCC(=O)Nc2ccc3OCCOc3c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J20 compound treatment 1968147.0 962.0 0.0 1973690.0 -145000.0 -0.24 -0.1672 -0.7023 3630914 CBKinase1_020918 Clc1ccc(cc1)C(=O)Cn2c3nc(nn3c4ccccc24)c5cccs5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J21 mock treatment 2057097.0 89900.0 0.15 2234377.0 115000.0 0.19 0.2414 0.9942 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J22 mock treatment 1860079.0 -107000.0 -0.18 1758300.0 -361000.0 -0.59 -0.5461 -0.8834 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J23 compound treatment 1630949.0 -336000.0 -0.57 1916000.0 -203000.0 -0.33 -0.6376 -0.9673 3630915 CBKinase1_020919 CC(C)OC(=O)CSc1nc(cc(c1C#N)C(F)(F)F)c2cccs2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 J24 compound treatment 2110001.0 143000.0 0.24 2050859.0 -68100.0 -0.11 0.0921 0.3458 3630916 CBKinase1_020920 OC(=O)c1cc(NC(=O)C2CC(=O)OC2c3ccccc3)ccc1O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K01 compound treatment 1702826.0 -264000.0 -0.45 1699489.0 -419000.0 -0.69 -0.8025 -0.9784 3630917 CBKinase1_020921 Cc1ccc(NC(=O)CSc2nnc(c3cccs3)n2C)cc1[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K02 compound treatment 1635563.0 -332000.0 -0.56 1966942.0 -152000.0 -0.25 -0.5731 -0.9331 3630918 CBKinase1_020922 Brc1cccc(c1)C2=NOC(C2)C(=O)NCc3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K03 compound treatment 1893208.0 -74000.0 -0.13 1781525.0 -337000.0 -0.55 -0.4795 -0.8458 3630919 CBKinase1_020923 COC(=O)c1cn(C(=O)CN2C(=O)c3ccccc3C2=O)c4ccccc14 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K04 compound treatment 1962182.0 -5000.0 -0.01 2126790.0 7870.0 0.01 0.0031 0.2027 3630920 CBKinase1_020924 CCOC(=O)c1c(C)c(C)sc1NC(=O)C2CC(=NO2)c3ccccc3Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K05 compound treatment 2118371.0 151000.0 0.26 1920256.0 -199000.0 -0.33 -0.0493 -0.119 3630921 CBKinase1_020925 Clc1cccc(NC(=O)CCn2cnc3ccccc3c2=O)c1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K06 compound treatment 2071436.0 104000.0 0.18 2426804.0 308000.0 0.5 0.4816 0.9009 3630922 CBKinase1_020926 Oc1ccccc1C2=NOC(C2)C(=O)Nc3sc4CCCCc4c3C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K07 mock treatment 2327289.0 360000.0 0.61 2139234.0 20300.0 0.03 0.4546 0.7446 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K08 mock treatment 2054326.0 87100.0 0.15 2246775.0 128000.0 0.21 0.2525 0.9852 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K09 compound treatment 2328312.0 361000.0 0.61 2361963.0 243000.0 0.4 0.7139 0.9785 3630923 CBKinase1_020927 CC(=O)c1ccc(NC(=O)Cn2cnc3ccccc3c2=O)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K10 compound treatment 2032212.0 65000.0 0.11 1947193.0 -172000.0 -0.28 -0.1212 -0.401 3630924 CBKinase1_020928 COc1ccc(CCN2C(=O)C(NC(=O)C(C)(C)C)(C3=C2CC(C)(C)CC3=O)C(F)(F)F)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K11 compound treatment 1538238.0 -429000.0 -0.73 1831212.0 -288000.0 -0.47 -0.8468 -0.9781 3630925 CBKinase1_020929 Fc1ccc(NC(=O)CC2N(Cc3ccco3)C(=O)N(C2=O)c4ccccc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K12 compound treatment 1218840.0 -748000.0 -1.27 1194321.0 -925000.0 -1.52 -1.9672 -0.996 3630926 CBKinase1_020930 OC(=O)C(Cc1c[nH]c2ccccc12)Nc3c4ccccc4nc5ccccc35 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K13 compound treatment 2285903.0 319000.0 0.54 2251787.0 133000.0 0.22 0.5355 0.9204 1430283 CBKinase1_020931 COc1ccc(NC(=O)CSc2nc(ccc2C#N)C3(CC4CC5CC(C4)C3)C5)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K14 compound treatment 2809560.0 842000.0 1.43 2963687.0 845000.0 1.38 1.9872 0.9999 3630927 CBKinase1_020932 CCOC(=O)c1c(NC(=O)CSc2nc3CCCCc3cc2C#N)sc4CCCCc14 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K15 mock treatment 2185760.0 219000.0 0.37 1964296.0 -155000.0 -0.25 0.0824 0.1838 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K16 mock treatment 2157502.0 190000.0 0.32 2383317.0 264000.0 0.43 0.5342 0.9893 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K17 compound treatment 1934699.0 -32500.0 -0.05 2171842.0 52900.0 0.09 0.0224 0.2185 3630928 CBKinase1_020933 CSc1nc(N)nc(SCC(=O)c2ccc(Cl)s2)c1C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K18 compound treatment 1935430.0 -31800.0 -0.05 2090917.0 -28000.0 -0.05 -0.0705 -0.9969 3630929 CBKinase1_020934 COc1ccc(cc1)c2ccc(C#N)c(SCC(=O)Nc3cccc(c3)C(F)(F)F)n2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K19 compound treatment 1993464.0 26300.0 0.04 2497367.0 378000.0 0.62 0.47 0.7559 3630930 CBKinase1_020935 FC(F)(F)c1cccc(NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3ccco3)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K20 compound treatment 2161811.0 195000.0 0.33 2399229.0 280000.0 0.46 0.5578 0.9867 3630931 CBKinase1_020936 OC(=O)CCSc1nc(cc(c1C#N)C(F)(F)F)c2ccc(Br)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K21 compound treatment 2193925.0 227000.0 0.38 2390702.0 272000.0 0.45 0.5863 0.9973 3630932 CBKinase1_020937 CCOC(=O)c1c(NC(=O)CSc2nc(C)cc(c2C#N)C(F)(F)F)sc3CCCCc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K22 compound treatment 1379289.0 -588000.0 -1.0 1848988.0 -270000.0 -0.44 -1.0165 -0.9334 3630933 CBKinase1_020938 Cc1ccc(Cl)cc1NC(=O)CSc2nc3CCCCc3c(c2C#N)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K23 mock treatment 1877910.0 -89300.0 -0.15 2111868.0 -7060.0 -0.01 -0.115 -0.759 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 K24 mock treatment 1798386.0 -169000.0 -0.29 2011572.0 -107000.0 -0.18 -0.3264 -0.9729 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L01 compound treatment 1529563.0 -438000.0 -0.74 1383217.0 -736000.0 -1.21 -1.3764 -0.9726 3630934 CBKinase1_020939 COc1cc(ccc1OCC(=O)O)C2NC(=O)NC(=C2C(=O)C)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L02 compound treatment 1663129.0 -304000.0 -0.51 1755860.0 -363000.0 -0.6 -0.7847 -0.9974 3630935 CBKinase1_020940 N#CCCSc1nnc(c2ccncc2)n1Cc3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L03 compound treatment 1911774.0 -55400.0 -0.09 1955054.0 -164000.0 -0.27 -0.2562 -0.9007 3630936 CBKinase1_020941 COc1cc(cc(Cl)c1OCC(=O)O)C2NC(=S)NC(=C2C(=O)C)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L04 compound treatment 1847448.0 -120000.0 -0.2 1196930.0 -922000.0 -1.51 -1.2118 -0.7948 3630937 CBKinase1_020942 O=C(Nc1ccc(cc1)S(=O)(=O)NCC2CCCO2)c3cc(nc4ccccc34)c5ccccc5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L05 compound treatment 1786327.0 -181000.0 -0.31 1373872.0 -745000.0 -1.22 -1.0799 -0.8578 3630938 CBKinase1_020943 CCOc1cc(cc(I)c1OCC(=O)O)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L06 compound treatment 1581426.0 -386000.0 -0.65 1719044.0 -400000.0 -0.66 -0.9251 -1.0 3630939 CBKinase1_020944 COc1cccc(NC(=O)CSc2nnc(c3cccc(OC)c3)n2c4ccc(Cl)cc4)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L07 mock treatment 1968132.0 947.0 0.0 2045058.0 -73900.0 -0.12 -0.0845 -0.6977 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L08 mock treatment 1805278.0 -162000.0 -0.27 2115009.0 -3920.0 -0.01 -0.1983 -0.7235 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L09 compound treatment 1780975.0 -186000.0 -0.32 1604269.0 -515000.0 -0.84 -0.8193 -0.9099 3630940 CBKinase1_020945 CCc1nnc(SCC(=O)Nc2ccc(cc2)[N+](=O)[O-])[nH]1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L10 compound treatment 1965496.0 -1690.0 0.0 1800488.0 -318000.0 -0.52 -0.371 -0.711 3630941 CBKinase1_020946 COc1ccccc1C(=O)CSc2nnc(c3ccccc3Cl)n2c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L11 compound treatment 1772600.0 -195000.0 -0.33 1899915.0 -219000.0 -0.36 -0.4867 -0.9991 3630942 CBKinase1_020947 Cn1c(=O)n(C)c2nc(OCc3ccco3)n(Cc4c(F)cccc4Cl)c2c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L12 compound treatment 1944681.0 -22500.0 -0.04 1909568.0 -209000.0 -0.34 -0.2696 -0.7808 3630943 CBKinase1_020948 CCn1c(SCC(=O)Nc2ccc(C)c(F)c2)nnc1c3cccc(Cl)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L13 compound treatment 1860007.0 -107000.0 -0.18 2088103.0 -30800.0 -0.05 -0.164 -0.8709 3630944 CBKinase1_020949 COC(=O)C(O)(CC(=O)Nc1ccc(OC(F)(F)F)cc1)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L14 compound treatment 1894535.0 -72600.0 -0.12 1970538.0 -148000.0 -0.24 -0.2589 -0.9501 3630945 CBKinase1_020950 CCOC(=O)CCSc1nnc2c3ccccc3n(C)c2n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L15 mock treatment 2040211.0 73000.0 0.12 2217630.0 98700.0 0.16 0.2018 0.9912 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L16 mock treatment 1961299.0 -5890.0 -0.01 2004927.0 -114000.0 -0.19 -0.1392 -0.7438 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L17 compound treatment 1664609.0 -303000.0 -0.51 1749078.0 -370000.0 -0.61 -0.7908 -0.9965 1416963 CBKinase1_020951 COC(=O)c1ccccc1NC(=O)CSc2nnnn2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L18 compound treatment 2010189.0 43000.0 0.07 1939499.0 -179000.0 -0.29 -0.1565 -0.5165 3630946 CBKinase1_020952 CC(=O)Cn1c2ccccc2n3nc(CCC(=O)O)c(=O)nc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L19 compound treatment 1977617.0 10400.0 0.02 1868946.0 -250000.0 -0.41 -0.2772 -0.676 3630947 CBKinase1_020953 Cn1nnnc1SCC(=O)Nc2ccc(Oc3ccc(Cl)cc3)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L20 compound treatment 2282577.0 315000.0 0.53 2503336.0 384000.0 0.63 0.823 0.9966 3630948 CBKinase1_020954 COc1ccc(cc1OC)C(=O)Cn2c3nc(nn3c4ccccc24)c5cccs5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L21 compound treatment 1738852.0 -228000.0 -0.39 1866372.0 -253000.0 -0.41 -0.566 -0.9994 3630949 CBKinase1_020955 CCOC(=O)NC(=O)CSc1nnc(C)s1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L22 compound treatment 1525511.0 -442000.0 -0.75 2131161.0 12200.0 0.02 -0.5145 -0.6879 3630950 CBKinase1_020956 CCOC(=O)c1c(CSc2cccc3cccnc23)nc4c5ccccc5ccn14 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L23 mock treatment 1216528.0 -751000.0 -1.27 2112491.0 -6430.0 -0.01 -0.9059 -0.713 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 L24 mock treatment 883843.0 -1080000.0 -1.83 1770961.0 -348000.0 -0.57 -1.6999 -0.8852 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M01 compound treatment 1607687.0 -359000.0 -0.61 1524083.0 -595000.0 -0.97 -1.1196 -0.9743 3630951 CBKinase1_020957 O=C(CCN1C(=O)c2ccccc2C1=O)Nc3ccc(Nc4ccccc4)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M02 compound treatment 1679484.0 -288000.0 -0.49 1851653.0 -267000.0 -0.44 -0.6541 -0.9986 3630952 CBKinase1_020958 Brc1cccc(c1)C2=NOC(C2)C(=O)NCCCN3CCOCC3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M03 compound treatment 1797955.0 -169000.0 -0.29 1805927.0 -313000.0 -0.51 -0.5653 -0.9621 1849851 CBKinase1_020959 Cc1ccc(NC(=O)CSc2nnc(N)s2)c(Br)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M04 compound treatment 2129854.0 163000.0 0.28 2054857.0 -64100.0 -0.1 0.1205 0.4088 3630953 CBKinase1_020960 Cc1nn(Cc2ccccc2Cl)c(C)c1NC(=O)C3CC(=NO3)c4ccc(Cl)cc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M05 compound treatment 1986466.0 19300.0 0.03 1959214.0 -160000.0 -0.26 -0.162 -0.6142 3630954 CBKinase1_020961 Cc1nn(C)c(C)c1NC(=O)CSc2nnc(c3cccc(Br)c3)n2c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M06 compound treatment 1954403.0 -12800.0 -0.02 1663316.0 -456000.0 -0.75 -0.5433 -0.7273 3630955 CBKinase1_020962 CCOC(=O)c1c(NC(=O)C2CC(=NO2)c3ccccc3O)sc4CCCCc14 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M07 compound treatment 2070239.0 103000.0 0.17 2037718.0 -81200.0 -0.13 0.0292 0.1333 3630956 CBKinase1_020963 CCn1c2ccccc2c3cc(NC(=O)CN4C(=O)c5ccccc5C4=O)ccc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M08 compound treatment 2056181.0 89000.0 0.15 1993831.0 -125000.0 -0.21 -0.0384 -0.1511 3630957 CBKinase1_020964 O=C(NCCN1CCOCC1)c2cc(on2)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M09 mock treatment 2097091.0 130000.0 0.22 2004792.0 -114000.0 -0.19 0.0232 0.0804 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M10 mock treatment 2296901.0 330000.0 0.56 1989252.0 -130000.0 -0.21 0.2444 0.4092 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M11 compound treatment 2117778.0 151000.0 0.25 2196772.0 77800.0 0.13 0.2705 0.9488 3630958 CBKinase1_020965 Fc1ccc(cc1Cl)N2C(=O)CC(SCc3nc4ccccc4[nH]3)C2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M12 compound treatment 2030830.0 63600.0 0.11 2074136.0 -44800.0 -0.07 0.0243 0.1862 3630959 CBKinase1_020966 O=C1N(CCc2c[nH]cn2)C(=O)c3cccc4cccc1c34 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M13 mock treatment 1991888.0 24700.0 0.04 2153033.0 34100.0 0.06 0.0691 0.9898 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M14 mock treatment 2034815.0 67600.0 0.11 2192342.0 73400.0 0.12 0.166 0.9997 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M15 compound treatment 2009855.0 42700.0 0.07 1920706.0 -198000.0 -0.32 -0.1786 -0.5368 3630960 CBKinase1_020967 COc1ccc(cc1)C(=O)CSc2nc(N)nc(SC)c2C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M16 compound treatment 1740284.0 -227000.0 -0.38 1745327.0 -374000.0 -0.61 -0.7045 -0.9748 3630961 CBKinase1_020968 COc1ccc(cc1)c2c3CCCc3nc(SCC(=O)Nc4cccc(F)c4)c2C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M17 compound treatment 2195119.0 228000.0 0.39 2137586.0 18700.0 0.03 0.2944 0.7608 3630962 CBKinase1_020969 Nc1cc(N)nc(SCc2cccnc2)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M18 compound treatment 1743706.0 -223000.0 -0.38 1717736.0 -401000.0 -0.66 -0.7324 -0.9655 3630963 CBKinase1_020970 CCOC(=O)Cc1[nH]nc2OC(=C(C#N)C(C(C)C)c12)N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M19 compound treatment 2240503.0 273000.0 0.46 2560853.0 442000.0 0.72 0.8393 0.9766 3630964 CBKinase1_020971 CSc1nc(N)nc(SCC(=O)Nc2ccc(Cl)cc2)c1C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M20 compound treatment 2143074.0 176000.0 0.3 2416185.0 297000.0 0.49 0.555 0.9721 3630965 CBKinase1_020972 CC(C)(C)c1cc(c(C#N)c(SCC(=O)Nc2sc3CCCCc3c2C#N)n1)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M21 compound treatment 2217611.0 250000.0 0.42 2155970.0 37000.0 0.06 0.3427 0.8002 3630966 CBKinase1_020973 CN(C)S(=O)(=O)N1CCN(CC(=O)Nc2ccc(F)cc2)CC1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M22 compound treatment 1784119.0 -183000.0 -0.31 2164998.0 46100.0 0.08 -0.1657 -0.5196 3630967 CBKinase1_020974 CCOC(=O)CCCSc1nc2CCC(C)Cc2c(c1C#N)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M23 compound treatment 1336381.0 -631000.0 -1.07 1888993.0 -230000.0 -0.38 -1.0215 -0.9021 3630968 CBKinase1_020975 Clc1ccc(Cl)c(NC(=O)CN2CCN(CC2)S(=O)(=O)c3ccc4ccccc4c3)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 M24 compound treatment 1692529.0 -275000.0 -0.46 1807877.0 -311000.0 -0.51 -0.6892 -0.9989 3630969 CBKinase1_020976 COC(=O)c1ccccc1NC(=O)CSc2nc3CCCCCc3cc2C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N01 compound treatment 990115.0 -977000.0 -1.65 1231870.0 -887000.0 -1.45 -2.1975 -0.9979 3630970 CBKinase1_020977 COC(=O)C1=C(C)NC(=C(C1c2cc(Br)ccc2OCC(=O)N)C(=O)OC)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N02 compound treatment 1403872.0 -563000.0 -0.95 1320386.0 -799000.0 -1.31 -1.5996 -0.9879 3630971 CBKinase1_020978 Cc1cc(ccc1Cl)n2c(SCC(=O)Nc3ccccc3)nnc2c4cccnc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N03 compound treatment 1243860.0 -723000.0 -1.22 1155308.0 -964000.0 -1.58 -1.9825 -0.9921 3630972 CBKinase1_020979 COC(=O)c1ccccc1NC(=O)C2=C(C)NC(=S)NC2c3ccc(OC4CCCC4)c(OC)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N04 compound treatment 1505877.0 -461000.0 -0.78 1473089.0 -646000.0 -1.06 -1.3006 -0.9888 3630973 CBKinase1_020980 Cc1ccnc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N05 compound treatment 1874134.0 -93100.0 -0.16 1222323.0 -897000.0 -1.47 -1.1504 -0.7784 3630974 CBKinase1_020981 O=C(CSC1=NCCS1)Nc2ccnc3ccccc23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N06 compound treatment 1466373.0 -501000.0 -0.85 1206352.0 -913000.0 -1.5 -1.657 -0.9638 3630975 CBKinase1_020982 Cc1ccccc1c2nnc(SCC(=O)Nc3cccc(Br)c3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N07 compound treatment 1878875.0 -88300.0 -0.15 1487289.0 -632000.0 -1.04 -0.8377 -0.8009 3630976 CBKinase1_020983 Cc1ccc(NC(=O)CSc2nc(C)c(C)c(O)n2)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N08 compound treatment 1455961.0 -511000.0 -0.87 1324229.0 -795000.0 -1.3 -1.5328 -0.9803 3630977 CBKinase1_020984 Cn1c(SCC(=O)Nc2ccc(Oc3ccccc3)cc2)nnc1c4ccccc4Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N09 mock treatment 1602223.0 -365000.0 -0.62 1402858.0 -716000.0 -1.17 -1.2667 -0.9551 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N10 mock treatment 1685177.0 -282000.0 -0.48 1805947.0 -313000.0 -0.51 -0.7002 -0.9994 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N11 compound treatment 1589895.0 -377000.0 -0.64 1805497.0 -313000.0 -0.51 -0.8148 -0.9942 1675629 CBKinase1_020985 CC(O)CNc1nc2n(C)c(=O)n(Cc3ccccc3F)c(=O)c2n1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N12 compound treatment 1528996.0 -438000.0 -0.74 1524369.0 -595000.0 -0.97 -1.2135 -0.9909 3630978 CBKinase1_020986 CCn1c(SCc2nc3ccccc3[nH]2)nnc1c4cccc(Cl)c4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N13 mock treatment 1260142.0 -707000.0 -1.2 1730226.0 -389000.0 -0.64 -1.2967 -0.9564 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N14 mock treatment 1481707.0 -485000.0 -0.82 1353740.0 -765000.0 -1.25 -1.4678 -0.979 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N15 compound treatment 1861599.0 -106000.0 -0.18 1525745.0 -593000.0 -0.97 -0.8138 -0.8233 3630979 CBKinase1_020987 CSc1cccc(NC(=O)Cn2cc(Br)c(n2)[N+](=O)[O-])c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N16 compound treatment 1325334.0 -642000.0 -1.09 1759025.0 -360000.0 -0.59 -1.1853 -0.9588 1566605 CBKinase1_020988 C(Sc1nnc2c3ccccc3n(Cc4ccccc4)c2n1)c5ccc6nonc6c5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N17 compound treatment 1159015.0 -808000.0 -1.37 1522398.0 -597000.0 -0.98 -1.6586 -0.9864 1445258 CBKinase1_020989 Cn1nnnc1SCC(=O)Nc2ccccc2C(=O)N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N18 compound treatment 1500001.0 -467000.0 -0.79 1658554.0 -460000.0 -0.75 -1.0927 -0.9997 3630980 CBKinase1_020990 OC(=O)CCc1nn2c3ccccc3n(CC(=O)c4cccs4)c2nc1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N19 compound treatment 1911315.0 -55900.0 -0.09 1657696.0 -461000.0 -0.76 -0.6014 -0.7894 3630981 CBKinase1_020991 Cn1nnnc1SCC(=O)Nc2cccc(NC(=O)C3(CC4CC5CC(C4)C3)C5)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N20 compound treatment 1820750.0 -146000.0 -0.25 1929700.0 -189000.0 -0.31 -0.3946 -0.9938 3630982 CBKinase1_020992 O=C(Cn1c2nc(nn2c3ccccc13)c4ccco4)c5ccccc5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N21 compound treatment 1773887.0 -193000.0 -0.33 1730649.0 -388000.0 -0.64 -0.6813 -0.9522 3630983 CBKinase1_020993 CCOC(=O)NC(=O)CSc1ccccn1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N22 compound treatment 1546129.0 -421000.0 -0.71 1342768.0 -776000.0 -1.27 -1.4034 -0.9625 3630984 CBKinase1_020994 Cc1nn2c(c1C(=O)CN3CCOCC3)n(C)c4ccccc42 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N23 compound treatment 1269312.0 -698000.0 -1.18 1112557.0 -1010000.0 -1.65 -2.0015 -0.9866 1986608 CBKinase1_020995 Cc1cc(NC(=O)c2sc(Nc3ccccc3F)nc2N)no1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 N24 compound treatment 1091420.0 -876000.0 -1.48 1099885.0 -1020000.0 -1.67 -2.2292 -0.9982 3630985 CBKinase1_020996 Cc1ccc(cc1)C2=NNC(=O)C(C2)c3cn(CCC#N)c4ccccc34 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O01 compound treatment 1056361.0 -911000.0 -1.54 1410471.0 -708000.0 -1.16 -1.9112 -0.9902 3630986 CBKinase1_020997 COC(=O)COc1cccc(NC(=O)c2ccccc2Cl)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O02 compound treatment 1633552.0 -334000.0 -0.56 1713320.0 -406000.0 -0.66 -0.8694 -0.9967 3630987 CBKinase1_020998 Brc1cccc(c1)C2=NOC(C2)C(=O)NCCCn3ccnc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O03 compound treatment 1611115.0 -356000.0 -0.6 1443195.0 -676000.0 -1.11 -1.2093 -0.9591 3630988 CBKinase1_020999 COc1ccc(OC)c(NC(=O)CSc2nnc(o2)c3ccco3)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O04 compound treatment 1608220.0 -359000.0 -0.61 1874565.0 -244000.0 -0.4 -0.7128 -0.9795 3630989 CBKinase1_021000 COC(=O)c1ccccc1NC(=O)C2CC(=NO2)c3ccccc3O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O05 compound treatment 1592179.0 -375000.0 -0.63 1860775.0 -258000.0 -0.42 -0.748 -0.9806 3630990 CBKinase1_021001 CC(Oc1ccc(cc1)C(C)(C)C)C(=O)Nc2nnc[nH]2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O06 compound treatment 1997201.0 30000.0 0.05 1953625.0 -165000.0 -0.27 -0.1556 -0.5646 3630991 CBKinase1_021002 CCCn1cc(NC(=O)C2CC(=NO2)c3ccccc3O)cn1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O07 compound treatment 1603341.0 -364000.0 -0.62 1706377.0 -413000.0 -0.68 -0.9136 -0.9989 3630992 CBKinase1_021003 [O-][N+](=O)c1cccc(c1)S(=O)(=O)NCCOc2cccc(Cl)c2Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O08 compound treatment 1416896.0 -550000.0 -0.93 1459804.0 -659000.0 -1.08 -1.4225 -0.9973 3630993 CBKinase1_021004 O=C(NCc1ccccn1)c2cc(on2)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O09 compound treatment 1619177.0 -348000.0 -0.59 1721273.0 -398000.0 -0.65 -0.8774 -0.9987 3630994 CBKinase1_021005 OC1(CC(=O)c2ccco2)C(=O)Nc3c1cccc3C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O10 compound treatment 1500235.0 -467000.0 -0.79 1644113.0 -475000.0 -0.78 -1.1091 -1.0 3630995 CBKinase1_021006 CC1(C)CC2=C(C(=O)C1)C(NC(=O)c3ccccc3)(C(=O)N2CC4CCCO4)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O11 mock treatment 1237927.0 -729000.0 -1.23 1715644.0 -403000.0 -0.66 -1.3402 -0.9571 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O12 mock treatment 1465307.0 -502000.0 -0.85 1806512.0 -312000.0 -0.51 -0.9628 -0.9706 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O13 compound treatment 1552630.0 -415000.0 -0.7 1811163.0 -308000.0 -0.5 -0.8528 -0.9869 3630996 CBKinase1_021007 Cc1cc(C)c(C#N)c(SCC(=O)Nc2ccc(cc2)C(=O)N)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O14 compound treatment 1783965.0 -183000.0 -0.31 1863210.0 -256000.0 -0.42 -0.5156 -0.989 3630997 CBKinase1_021008 FC(F)(F)c1cc(nc(SCC(=O)Nc2sc3CCCc3c2C#N)c1C#N)c4cccs4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O15 compound treatment 1715246.0 -252000.0 -0.43 1780107.0 -339000.0 -0.56 -0.6942 -0.9915 3630998 CBKinase1_021009 COC(=O)C1(C#N)C(C(N2C=C(C=CC21)C(=O)C)C(=O)N)c3ccsc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O16 compound treatment 1986303.0 19100.0 0.03 2184702.0 65800.0 0.11 0.0991 0.8806 3630999 CBKinase1_021010 CCOC(=O)c1c(NC(=O)CSc2nc(C)ccc2C#N)sc3CCCc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O17 compound treatment 1754373.0 -213000.0 -0.36 1761453.0 -357000.0 -0.59 -0.669 -0.9727 3631000 CBKinase1_021011 CSc1nc(N)nc(SC(C(=O)O)c2ccccc2)c1C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O18 compound treatment 1070226.0 -897000.0 -1.52 1579778.0 -539000.0 -0.88 -1.6984 -0.9668 3631001 CBKinase1_021012 CCOC(=O)Cc1[nH]nc2OC(=C(C#N)C(C3CCC=CC3)c12)N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O19 compound treatment 1782914.0 -184000.0 -0.31 2176439.0 57500.0 0.09 -0.1539 -0.4723 3631002 CBKinase1_021013 COC(=O)C(C#N)C(c1c(C)[nH]nc1O)c2cccnc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O20 compound treatment 1967164.0 -20.7 0.0 1730387.0 -389000.0 -0.64 -0.4503 -0.7071 3631003 CBKinase1_021014 Oc1nc(O)c2sc3nc(cc(c3c2n1)C(F)(F)F)c4ccc5OCCOc5c4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O21 compound treatment 1749422.0 -218000.0 -0.37 2265158.0 146000.0 0.24 -0.0912 -0.2074 3631004 CBKinase1_021015 CN(C)S(=O)(=O)N1CCN(CC(=O)Nc2ccc(Br)cc2)CC1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O22 compound treatment 2001239.0 34100.0 0.06 1940830.0 -178000.0 -0.29 -0.1656 -0.5567 3631005 CBKinase1_021016 CN(C)c1ccc(NC(=O)CSc2nc3CCCCCCc3c(c2C#N)C(F)(F)F)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O23 compound treatment 967877.0 -999000.0 -1.69 1306095.0 -813000.0 -1.33 -2.1381 -0.993 3631006 CBKinase1_021017 [O-][N+](=O)c1cccc(c1)S(=O)(=O)N2CCN(CC(=O)Nc3cc(Cl)ccc3Cl)CC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 O24 compound treatment 1284723.0 -682000.0 -1.16 1497986.0 -621000.0 -1.02 -1.5364 -0.998 3631007 CBKinase1_021018 CC(=O)N1CCc2nc(SCC(=O)Nc3cccc(C#N)c3)c(C#N)c(c2C1)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P01 compound treatment 995087.0 -972000.0 -1.65 1334602.0 -784000.0 -1.29 -2.0725 -0.9925 3631008 CBKinase1_021019 NC(=O)COc1ccc(cc1)C2NC(=S)NC(=C2C(=O)c3ccccc3)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P02 compound treatment 1210053.0 -757000.0 -1.28 1460461.0 -658000.0 -1.08 -1.6693 -0.9963 3631009 CBKinase1_021020 Cn1c(SCC(=O)Nc2ccccc2Cl)nnc1c3cccnc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P03 compound treatment 1442546.0 -525000.0 -0.89 1286357.0 -833000.0 -1.36 -1.5928 -0.9784 3631010 CBKinase1_021021 CCOc1cc(cc(Br)c1OCC(=O)N)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P04 compound treatment 1183332.0 -784000.0 -1.33 1661999.0 -457000.0 -0.75 -1.4677 -0.9633 1191363 CBKinase1_021022 Cn1c(=O)n(C)c2ncn(CC(=O)N3CCN(CC3)C(=O)c4ccco4)c2c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P05 compound treatment 1444913.0 -522000.0 -0.88 1563086.0 -556000.0 -0.91 -1.2693 -0.9999 3631011 CBKinase1_021023 CCc1nnc(SCC(=O)Nc2ccc(cc2)C(=O)C)[nH]1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P06 compound treatment 1558144.0 -409000.0 -0.69 1675770.0 -443000.0 -0.73 -1.0031 -0.9997 3631012 CBKinase1_021024 Cc1ccccc1c2nnc(SCC(=O)Nc3ccc(F)c(F)c3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P07 compound treatment 1461712.0 -505000.0 -0.86 1519232.0 -600000.0 -0.98 -1.3 -0.9976 3631013 CBKinase1_021025 Cc1ccc(NC(=O)CSc2nncc3ccccc23)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P08 compound treatment 1503636.0 -464000.0 -0.78 1250476.0 -868000.0 -1.42 -1.5612 -0.9606 3631014 CBKinase1_021026 Cn1c(SCC(=O)Nc2ccc(cc2)S(=O)(=O)N)nnc1c3ccccc3Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P09 compound treatment 1155873.0 -811000.0 -1.37 1604838.0 -514000.0 -0.84 -1.5668 -0.9725 3631015 CBKinase1_021027 COc1ccc(cc1)n2c(S)nnc2Cn3ncc4ccccc4c3=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P10 compound treatment 1345940.0 -621000.0 -1.05 1458160.0 -661000.0 -1.08 -1.5093 -0.9999 3631016 CBKinase1_021028 Cn1c(SCC(=O)N)nnc1c2cccc(Cl)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P11 mock treatment 1460095.0 -507000.0 -0.86 1612884.0 -506000.0 -0.83 -1.1934 -0.9999 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P12 mock treatment 1801792.0 -165000.0 -0.28 1788192.0 -331000.0 -0.54 -0.5812 -0.9527 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P13 compound treatment 1585907.0 -381000.0 -0.65 1674685.0 -444000.0 -0.73 -0.9712 -0.9982 3631017 CBKinase1_021029 COC(=O)C(O)(CC(=O)Nc1ccc(Cl)cc1F)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P14 compound treatment 1384786.0 -582000.0 -0.99 1535548.0 -583000.0 -0.96 -1.3731 -0.9999 3631018 CBKinase1_021030 COC(=O)C(C)Sc1nnc2c3ccccc3n(Cc4ccccc4)c2n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P15 compound treatment 1493431.0 -474000.0 -0.8 1496693.0 -622000.0 -1.02 -1.2881 -0.9929 3631019 CBKinase1_021031 CC(NC(=O)Cn1cc(Br)c(n1)[N+](=O)[O-])c2ccccc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P16 compound treatment 1482230.0 -485000.0 -0.82 1595316.0 -524000.0 -0.86 -1.1872 -0.9998 1226338 CBKinase1_021032 CCn1cc(C(=O)OCc2ccc3nonc3c2)c(=O)c4ccc(C)nc14 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P17 compound treatment 1591126.0 -376000.0 -0.64 1104140.0 -1010000.0 -1.66 -1.6261 -0.9132 3631020 CBKinase1_021033 Cn1nnnc1SCC(=O)Nc2cccc(c2)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P18 compound treatment 1551893.0 -415000.0 -0.7 1586795.0 -532000.0 -0.87 -1.1137 -0.9943 3631021 CBKinase1_021034 OC(=O)CCc1nn2c3ccccc3n(CCN4CCCCC4)c2nc1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P19 compound treatment 1681662.0 -286000.0 -0.48 1744767.0 -374000.0 -0.61 -0.7753 -0.9931 1587901 CBKinase1_021035 COc1cc2c(cc1NC(=O)CSc3nnnn3C)oc4ccccc42 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P20 compound treatment 1682586.0 -285000.0 -0.48 1659926.0 -459000.0 -0.75 -0.8726 -0.9768 3631022 CBKinase1_021036 O=C(Cn1c2nc(nn2c3ccccc13)c4ccccc4)c5ccccc5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P21 compound treatment 2007352.0 40200.0 0.07 1985031.0 -134000.0 -0.22 -0.1071 -0.4661 1480007 CBKinase1_021037 OC(=O)c1cccc(NC(=O)CSc2nnnn2c3ccccc3)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P22 compound treatment 1805291.0 -162000.0 -0.27 1566300.0 -553000.0 -0.91 -0.8342 -0.8816 1432034 CBKinase1_021038 Cc1cc(C)nc(SCC(=O)Nc2nonc2N)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P23 compound treatment 1396047.0 -571000.0 -0.97 1729181.0 -390000.0 -0.64 -1.1353 -0.9798 3631023 CBKinase1_021039 Clc1cccc(Cl)c1NC(=O)CSc2nc3CCCc3c(c2C#N)c4cccnc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2389 P24 compound treatment 1306161.0 -661000.0 -1.12 1177908.0 -941000.0 -1.54 -1.8817 -0.9876 3631024 CBKinase1_021040 Cc1cc(Oc2ccccc2)nc(SCC(=O)Nc3ccc(Cl)cc3Cl)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A01 compound treatment 1045233.0 -476000.0 -0.81 1166990.0 -562000.0 -0.92 -1.2214 -0.9977 3631025 CBKinase1_021041 Fc1ccc(NC(=O)CSc2nnc(c3cccc(Cl)c3)n2c4ccccc4)cc1F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A02 compound treatment 1258863.0 -262000.0 -0.44 1453503.0 -276000.0 -0.45 -0.6336 -1.0 3631026 CBKinase1_021042 Fc1ccc(cc1)N2C(=O)CC(SCCc3nc4ccccc4[nH]3)C2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A03 compound treatment 1192636.0 -328000.0 -0.56 1709796.0 -19600.0 -0.03 -0.4159 -0.7467 3631027 CBKinase1_021043 CCn1c(SCC(=O)c2ccc(C)cc2)nnc1c3ccncc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A04 compound treatment 1201895.0 -319000.0 -0.54 1807989.0 78600.0 0.13 -0.291 -0.5239 3631028 CBKinase1_021044 COc1ccc(NC(=O)C(C)N(c2ccc(Cl)cc2)S(=O)(=O)C)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A05 compound treatment 1533142.0 12000.0 0.02 1435567.0 -294000.0 -0.48 -0.3261 -0.6766 3631029 CBKinase1_021045 Cc1cccc(c1)c2nnc(SCC(=O)Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A06 compound treatment 1476451.0 -44700.0 -0.08 1741855.0 12500.0 0.02 -0.039 -0.4984 3631030 CBKinase1_021046 Cc1ccc(C)c(NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A07 compound treatment 1009756.0 -511000.0 -0.87 1598629.0 -131000.0 -0.21 -0.7636 -0.8563 3631031 CBKinase1_021047 COc1ccccc1c2nnc(SCC(=O)c3ccc(NC(=O)C)cc3)o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A08 compound treatment 1470437.0 -50700.0 -0.09 1589704.0 -140000.0 -0.23 -0.2225 -0.9102 3631032 CBKinase1_021048 Cc1ccc(NC(=O)CSc2nc(N)c(c3ccccc3)c(=O)[nH]2)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A09 compound treatment 1118923.0 -402000.0 -0.68 1862329.0 133000.0 0.22 -0.3273 -0.458 3631033 CBKinase1_021049 CS(=O)(=O)N(CC(=O)NC1CCCC1)c2cc(Cl)c(Cl)cc2Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A10 compound treatment 1348108.0 -173000.0 -0.29 1830370.0 101000.0 0.17 -0.0901 -0.2678 3631034 CBKinase1_021050 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)Nc2ccccc2C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A11 compound treatment 1593167.0 72100.0 0.12 1871354.0 142000.0 0.23 0.2507 0.9546 3631035 CBKinase1_021051 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)Nc2ccccc2Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A12 compound treatment 1246372.0 -275000.0 -0.47 1443745.0 -286000.0 -0.47 -0.6599 -1.0 3631036 CBKinase1_021052 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)N2CCOCC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A13 mock treatment 1252848.0 -268000.0 -0.45 1663711.0 -65700.0 -0.11 -0.3972 -0.8512 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A14 mock treatment 1421717.0 -99400.0 -0.17 1658861.0 -70500.0 -0.12 -0.2007 -0.9832 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A15 compound treatment 1222476.0 -299000.0 -0.51 1323853.0 -406000.0 -0.66 -0.8274 -0.9909 3631037 CBKinase1_021053 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2ccc(I)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A16 compound treatment 1255745.0 -265000.0 -0.45 1079658.0 -650000.0 -1.06 -1.0706 -0.9263 3631038 CBKinase1_021054 CCN(CC(=O)N)S(=O)(=O)c1ccc2ccccc2c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A17 compound treatment 1329608.0 -192000.0 -0.32 1833605.0 104000.0 0.17 -0.1085 -0.296 3631039 CBKinase1_021055 COc1ccc(OC)c(NC(=O)CSc2nc3sc(C)c(C)c3c(=O)n2c4ccccc4)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A18 compound treatment 924527.0 -597000.0 -1.01 1546923.0 -182000.0 -0.3 -0.9255 -0.8788 3631040 CBKinase1_021056 CC(=O)c1cccc(NC(=O)CN(Cc2ccc(Cl)cc2)S(=O)(=O)C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A19 compound treatment 1288259.0 -233000.0 -0.39 1965492.0 236000.0 0.39 -0.0051 -0.0093 3178745 CBKinase1_021057 C(On1nnc2ccccc12)c3ccccc3COn4nnc5ccccc45 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A20 compound treatment 1001113.0 -520000.0 -0.88 1356652.0 -373000.0 -0.61 -1.0544 -0.9841 3631041 CBKinase1_021058 CC(=O)c1cccc(c1)N(CC(=O)N2CCCC2)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A21 compound treatment 1166592.0 -355000.0 -0.6 1434748.0 -295000.0 -0.48 -0.7658 -0.9942 1672727 CBKinase1_021059 Cn1c(=O)n(C)c2nc(NCC(O)c3ccccc3)n(Cc4ccc(F)cc4)c2c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A22 compound treatment 1228323.0 -293000.0 -0.5 1371548.0 -358000.0 -0.59 -0.7652 -0.9965 3631042 CBKinase1_021060 CCOC(=O)CN(c1c(C)cccc1C)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A23 compound treatment 1166932.0 -354000.0 -0.6 1300781.0 -429000.0 -0.7 -0.9206 -0.9969 3631043 CBKinase1_021061 Cn1c(OCc2cccnc2)nc3n(C)c(=O)n(Cc4ccc(Cl)c(Cl)c4)c(=O)c13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 A24 compound treatment 1059927.0 -461000.0 -0.78 1084661.0 -645000.0 -1.06 -1.2992 -0.9889 3631044 CBKinase1_021062 CC(N(c1cc(C)cc(C)c1)S(=O)(=O)C)C(=O)Nc2cccc(Cl)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B01 compound treatment 1090136.0 -431000.0 -0.73 1529171.0 -200000.0 -0.33 -0.7479 -0.9349 3631045 CBKinase1_021063 CNC(=O)CN(c1ccc(cc1)C2(CC3CC4CC(C3)C2)C4)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B02 compound treatment 1379861.0 -141000.0 -0.24 1884260.0 155000.0 0.25 0.0104 0.0298 3631046 CBKinase1_021064 COc1ccccc1NC(=O)C2=C(C)Nc3ncnn3C2c4ccccc4C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B03 compound treatment 1296263.0 -225000.0 -0.38 1809041.0 79600.0 0.13 -0.1768 -0.4395 3631047 CBKinase1_021065 COc1ccccc1NC(=O)C(C)N2c3cccc4cccc(c34)S2(=O)=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B04 compound treatment 1409186.0 -112000.0 -0.19 1999061.0 270000.0 0.44 0.1785 0.3713 3631048 CBKinase1_021066 COC(=O)CNC(=O)c1cc2cc(Cl)ccc2oc1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B05 compound treatment 1560015.0 38900.0 0.07 1910635.0 181000.0 0.3 0.2566 0.8434 3631049 CBKinase1_021067 Clc1cccc(c1)c2nnc(SCC(=O)Nc3ccccc3)o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B06 compound treatment 1364642.0 -156000.0 -0.26 1871662.0 142000.0 0.23 -0.0224 -0.0636 3631050 CBKinase1_021068 OC(=O)C1C(C2CCC1O2)C(=O)Nc3ccc(cc3)S(=O)(=O)N4CCc5ccccc45 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B07 compound treatment 1681902.0 161000.0 0.27 1815296.0 85900.0 0.14 0.292 0.9529 3631051 CBKinase1_021069 Fc1ccc(NC(=O)CC2Nc3cccc4cccc(NC2=O)c34)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B08 compound treatment 1217021.0 -304000.0 -0.51 1824848.0 95400.0 0.16 -0.2534 -0.471 3631052 CBKinase1_021070 CC1(C)CC(=O)c2c(O)cc(OCC(=O)c3ccc(cc3)c4ccccc4)cc2O1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B09 compound treatment 1167435.0 -354000.0 -0.6 1697761.0 -31600.0 -0.05 -0.46 -0.7655 3631053 CBKinase1_021071 CCOc1ccc2NC(=O)C(CC(=O)Nc3ccccc3[N+](=O)[O-])Sc2c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B10 compound treatment 1474608.0 -46500.0 -0.08 2099100.0 370000.0 0.61 0.3728 0.6101 3631054 CBKinase1_021072 Cc1nn(c(OC(=O)c2ccccc2C(F)(F)F)c1S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B11 compound treatment 1352290.0 -169000.0 -0.29 1465824.0 -264000.0 -0.43 -0.5075 -0.9799 3030932 CBKinase1_021073 Cn1c(=O)oc2cc(ccc12)S(=O)(=O)NCc3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B12 compound treatment 1540540.0 19400.0 0.03 1929632.0 200000.0 0.33 0.2553 0.7741 3631055 CBKinase1_021074 Cn1c(SCC(=O)Nc2c(F)cc(F)cc2Br)nnc1c3cccnc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B13 mock treatment 1200130.0 -321000.0 -0.54 1841813.0 112000.0 0.18 -0.2539 -0.4426 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B14 mock treatment 1229453.0 -292000.0 -0.49 1742290.0 12900.0 0.02 -0.3342 -0.6762 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B15 compound treatment 1169383.0 -352000.0 -0.6 1345786.0 -384000.0 -0.63 -0.8656 -0.9996 3631056 CBKinase1_021075 CC(NS(=O)(=O)c1ccccc1)C(=O)Nc2ccc(Oc3ccccc3)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B16 compound treatment 1242709.0 -278000.0 -0.47 1515303.0 -214000.0 -0.35 -0.5813 -0.9895 3631057 CBKinase1_021076 CCn1c(SCC(=O)Nc2ccc3OCCOc3c2)nnc1c4cccs4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B17 compound treatment 1608263.0 87100.0 0.15 1778595.0 49200.0 0.08 0.1613 0.9596 3631058 CBKinase1_021077 Brc1ccc(NC(=O)CSc2nnc(c3cnccn3)n2c4ccccc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B18 compound treatment 1275127.0 -246000.0 -0.42 1616089.0 -113000.0 -0.19 -0.4257 -0.9338 3631059 CBKinase1_021078 CCn1c(SCC(=O)Nc2ccc(cc2)C(=O)N)nnc1c3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B19 compound treatment 1503058.0 -18100.0 -0.03 1778676.0 49300.0 0.08 0.0355 0.411 3631060 CBKinase1_021079 CC(C)OC(=O)CSc1nnc(c2cnccn2)n1c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B20 compound treatment 1078726.0 -442000.0 -0.75 1429977.0 -299000.0 -0.49 -0.8765 -0.979 3631061 CBKinase1_021080 Cc1sc2ncnc(SCC(=O)Nc3ccccc3c4ccccc4)c2c1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B21 compound treatment 1239555.0 -282000.0 -0.48 1554849.0 -175000.0 -0.29 -0.5393 -0.9702 3631062 CBKinase1_021081 Cc1ccc(cc1)n2c(SCC(=O)N)nnc2c3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B22 compound treatment 1139245.0 -382000.0 -0.65 1585141.0 -144000.0 -0.24 -0.6242 -0.907 3631063 CBKinase1_021082 CN(C)c1ccc(NC(=O)CSc2nnc(c3cnccn3)n2C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B23 compound treatment 849307.0 -672000.0 -1.14 1216721.0 -513000.0 -0.84 -1.3982 -0.9889 3631064 CBKinase1_021083 Cn1c(SCc2nc3ccccc3s2)nnc1c4cccnc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 B24 compound treatment 1422966.0 -98100.0 -0.17 1504844.0 -225000.0 -0.37 -0.3777 -0.9354 3631065 CBKinase1_021084 OC(=O)c1ccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccc(Cl)cc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C01 compound treatment 1414500.0 -107000.0 -0.18 1615525.0 -114000.0 -0.19 -0.2596 -0.9999 3631066 CBKinase1_021085 Clc1cccc(c1)c2nnc(SCC(=O)Nc3ccccc3c4ccccc4)n2c5ccccc5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C02 compound treatment 1499073.0 -22000.0 -0.04 1827166.0 97800.0 0.16 0.0869 0.5283 3631067 CBKinase1_021086 [O-][N+](=O)c1ccc(NC(=O)CN2C(=O)COc3ccc(Cl)cc23)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C03 compound treatment 1643804.0 123000.0 0.21 1952658.0 223000.0 0.37 0.4056 0.964 3631068 CBKinase1_021087 CCn1c(SCC(=O)c2cc(OC)ccc2OC)nnc1c3ccncc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C04 compound treatment 1822592.0 301000.0 0.51 1994760.0 265000.0 0.43 0.6684 0.9968 3631069 CBKinase1_021088 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2cc(C)cc(C)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C05 compound treatment 1724924.0 204000.0 0.34 1967218.0 238000.0 0.39 0.5195 0.9981 3631070 CBKinase1_021089 CCn1c(SCC(=O)Nc2ccccc2C(F)(F)F)nnc1c3cccc(C)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C06 compound treatment 1539877.0 18800.0 0.03 1691572.0 -37800.0 -0.06 -0.0214 -0.307 3631071 CBKinase1_021090 Cc1ccc(NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C07 compound treatment 1798442.0 277000.0 0.47 1109339.0 -620000.0 -1.02 -0.3866 -0.3454 3631072 CBKinase1_021091 CC(=O)Nc1ccc(cc1)C(=O)CSc2nnc(C)s2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C08 compound treatment 1668968.0 148000.0 0.25 1651829.0 -77600.0 -0.13 0.0871 0.3102 3631073 CBKinase1_021092 Nc1nc(SCC(=O)N2CCCc3ccccc23)[nH]c(=O)c1c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C09 compound treatment 1443629.0 -77500.0 -0.13 1653766.0 -75600.0 -0.12 -0.1804 -0.9996 3631074 CBKinase1_021093 CN(C)C(=O)CN(c1cccc(c1)C(=O)C)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C10 compound treatment 1453714.0 -67400.0 -0.11 1750977.0 21600.0 0.04 -0.0557 -0.4661 3631075 CBKinase1_021094 COc1ccccc1NC(=O)CN(C)S(=O)(=O)c2cc(C)ccc2OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C11 mock treatment 1365250.0 -156000.0 -0.26 1663618.0 -65800.0 -0.11 -0.2628 -0.922 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C12 mock treatment 1611225.0 90100.0 0.15 2076362.0 347000.0 0.57 0.5099 0.8662 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C13 compound treatment 1589410.0 68300.0 0.12 2047810.0 318000.0 0.52 0.4507 0.8433 3631076 CBKinase1_021095 COc1ccc(cc1)S(=O)(=O)N(CC(=O)N)c2ccc(F)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C14 compound treatment 1542178.0 21100.0 0.04 1614656.0 -115000.0 -0.19 -0.1078 -0.563 3631077 CBKinase1_021096 CCN(CC(=O)Nc1cccc(c1)C(=O)C)S(=O)(=O)c2ccc(C)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C15 mock treatment 1730032.0 209000.0 0.35 1366335.0 -363000.0 -0.6 -0.1707 -0.2466 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C16 mock treatment 1599328.0 78200.0 0.13 1254576.0 -475000.0 -0.78 -0.4566 -0.5785 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C17 compound treatment 1752846.0 232000.0 0.39 1289992.0 -439000.0 -0.72 -0.2319 -0.2827 3631078 CBKinase1_021097 COc1ccc(OC)c(NC(=O)CSc2nc3sc4CCCCc4c3c(=O)n2c5ccccc5)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C18 compound treatment 1567814.0 46700.0 0.08 1369675.0 -360000.0 -0.59 -0.361 -0.6069 3631079 CBKinase1_021098 CS(=O)(=O)N(CC(=O)Nc1cccc(c1)[N+](=O)[O-])Cc2ccc(Cl)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C19 compound treatment 1594288.0 73200.0 0.12 1642403.0 -87000.0 -0.14 -0.0132 -0.0701 3631080 CBKinase1_021099 CC(CCO)Nc1nc2n(C)c(=O)n(C)c(=O)c2[nH]1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C20 compound treatment 1472759.0 -48400.0 -0.08 1354602.0 -375000.0 -0.61 -0.4922 -0.7943 3631081 CBKinase1_021100 Cc1cc(C)cc(NC(=O)CN(c2ccc(Cl)cc2Cl)S(=O)(=O)C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C21 compound treatment 1459906.0 -61200.0 -0.1 1436721.0 -293000.0 -0.48 -0.4124 -0.8405 1735278 CBKinase1_021101 Cn1c(=O)n(C)c2nc(NCCO)n(CCc3ccccc3)c2c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C22 compound treatment 1319791.0 -201000.0 -0.34 1507487.0 -222000.0 -0.36 -0.4981 -0.9995 3631082 CBKinase1_021102 Cc1cccc(c1)N(CC(=O)NC(C)(C)C)S(=O)(=O)c2ccc(Cl)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C23 compound treatment 1173743.0 -347000.0 -0.59 1192541.0 -537000.0 -0.88 -1.0379 -0.9808 3631083 CBKinase1_021103 Cn1c(=O)n(C)c2nc(NCc3cccnc3)n(Cc4ccc(F)cc4)c2c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 C24 compound treatment 1271939.0 -249000.0 -0.42 1867972.0 139000.0 0.23 -0.1377 -0.2874 3631084 CBKinase1_021104 COc1ccc(OC)c(NC(=O)c2ccc(cc2)N(C)S(=O)(=O)c3ccc(OC)c(OC)c3)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D01 compound treatment 1357949.0 -163000.0 -0.28 1322969.0 -406000.0 -0.67 -0.6663 -0.924 3631085 CBKinase1_021105 COc1cccc(NC(=O)C(C)N(c2ccc(C)c(C)c2)S(=O)(=O)C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D02 compound treatment 1443670.0 -77400.0 -0.13 1921908.0 193000.0 0.32 0.1304 0.3817 3631086 CBKinase1_021106 COc1ccccc1NC(=O)C2=C(C)Nc3ncnn3C2c4ccc(cc4)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D03 compound treatment 1541788.0 20700.0 0.03 1956532.0 227000.0 0.37 0.288 0.7702 3631087 CBKinase1_021107 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)Nc2ccc(I)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D04 compound treatment 1687446.0 166000.0 0.28 2101022.0 372000.0 0.61 0.6297 0.9386 3631088 CBKinase1_021108 CC(=O)c1cccc(NC(=O)c2ccsc2NC(=O)COc3ccccc3)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D05 compound treatment 1676516.0 155000.0 0.26 2104985.0 376000.0 0.62 0.6213 0.9281 3631089 CBKinase1_021109 COc1ccccc1c2nnc(SCC(=O)Nc3ccccc3)o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D06 compound treatment 1905599.0 384000.0 0.65 2094432.0 365000.0 0.6 0.8832 0.9991 3122535 CBKinase1_021110 Cc1cc(no1)C(=O)NCc2cccnc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D07 compound treatment 1628778.0 108000.0 0.18 1637850.0 -91600.0 -0.15 0.0228 0.0964 3631090 CBKinase1_021111 CCOC(=O)c1ccc(NC(=O)CC2Nc3cccc4cccc(NC2=O)c34)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D08 compound treatment 1733311.0 212000.0 0.36 2069950.0 341000.0 0.56 0.6486 0.9773 3631091 CBKinase1_021112 Cc1sc2nc(SCC(=O)Nc3c(F)cc(F)cc3Br)n(C)c(=O)c2c1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D09 compound treatment 1842021.0 321000.0 0.54 1838122.0 109000.0 0.18 0.5101 0.8923 3631092 CBKinase1_021113 Cc1ccc(cc1[N+](=O)[O-])C(=O)NC(=S)NCc2ccco2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D10 compound treatment 1532085.0 11000.0 0.02 1686366.0 -43000.0 -0.07 -0.0367 -0.5038 3631093 CBKinase1_021114 COc1ccc(CCN2C(c3c(oc4ccc(C)cc4c3=O)C2=O)c5cccc(c5)[N+](=O)[O-])cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D11 mock treatment 1805567.0 284000.0 0.48 1956094.0 227000.0 0.37 0.6032 0.9918 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D12 mock treatment 1809173.0 288000.0 0.49 2129826.0 400000.0 0.66 0.8088 0.9893 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D13 compound treatment 1611580.0 90500.0 0.15 1916403.0 187000.0 0.31 0.325 0.9486 3631094 CBKinase1_021115 COc1ccc(cc1)N(C(=O)C2CCCCC2)S(=O)(=O)c3cccc4cccnc34 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D14 compound treatment 1708738.0 188000.0 0.32 1935715.0 206000.0 0.34 0.4637 0.9995 3631095 CBKinase1_021116 Cn1c(SCc2ccc(cc2)[N+](=O)[O-])nnc1c3ccccn3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D15 mock treatment 1747572.0 226000.0 0.38 2002586.0 273000.0 0.45 0.5876 0.997 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D16 mock treatment 1875601.0 354000.0 0.6 1938944.0 210000.0 0.34 0.6671 0.9649 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D17 compound treatment 1689160.0 168000.0 0.28 1865503.0 136000.0 0.22 0.3589 0.9928 3631096 CBKinase1_021117 NC(=O)CSc1nnc(c2cnccn2)n1c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D18 compound treatment 1774673.0 254000.0 0.43 1727629.0 -1770.0 0.0 0.3014 0.7023 3631097 CBKinase1_021118 CCn1c(SCC(=O)Nc2ccc(F)cc2F)nnc1c3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D19 compound treatment 1539238.0 18100.0 0.03 1897057.0 168000.0 0.27 0.216 0.7812 3631098 CBKinase1_021119 Cc1ccc(cc1)n2c(SCC(=O)Nc3ccc(F)c(F)c3)nnc2c4cnccn4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D20 compound treatment 1552951.0 31800.0 0.05 1429580.0 -300000.0 -0.49 -0.3093 -0.6258 3631099 CBKinase1_021120 CN(C)c1ccc(NC(=O)CSc2ncnc3scc(c4ccc(C)cc4)c23)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D21 compound treatment 1424141.0 -97000.0 -0.16 1735581.0 6180.0 0.01 -0.1089 -0.6622 3631100 CBKinase1_021121 Cc1ccc(cc1)n2c(SCC(=O)c3ccc(Cl)cc3)nnc2c4ccco4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D22 compound treatment 1494748.0 -26400.0 -0.04 1741232.0 11800.0 0.02 -0.0179 -0.3669 3631101 CBKinase1_021122 CC(C)(C)C(=O)CSc1nnc(c2ccco2)n1Cc3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D23 compound treatment 1604451.0 83300.0 0.14 1871906.0 143000.0 0.23 0.2649 0.9709 3631102 CBKinase1_021123 COc1ccc(cc1[N+](=O)[O-])S(=O)(=O)NCc2ccco2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 D24 compound treatment 1340411.0 -181000.0 -0.31 1445715.0 -284000.0 -0.46 -0.545 -0.9794 3631103 CBKinase1_021124 Clc1ccc(cc1)n2c(SCc3nc4ccccc4[nH]3)nnc2c5ccncc5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E01 mock treatment 1108324.0 -413000.0 -0.7 1551943.0 -177000.0 -0.29 -0.6997 -0.9245 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E02 mock treatment 1556714.0 35600.0 0.06 2004148.0 275000.0 0.45 0.361 0.7947 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E03 compound treatment 1754414.0 233000.0 0.39 2038572.0 309000.0 0.51 0.6375 0.9924 3631104 CBKinase1_021125 FC(F)(F)c1ccc(Cl)c(NC(=O)CSc2nnc(c3cccnc3)n2c4ccccc4)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E04 compound treatment 1860869.0 340000.0 0.58 2166464.0 437000.0 0.72 0.9132 0.9941 3631105 CBKinase1_021126 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2ccccc2Br 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E05 compound treatment 1892940.0 372000.0 0.63 1809540.0 80100.0 0.13 0.5379 0.8366 3631106 CBKinase1_021127 COc1ccccc1c2nnc(SCC(=O)c3ccc(cc3)[N+](=O)[O-])o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E06 compound treatment 1845667.0 325000.0 0.55 2113892.0 384000.0 0.63 0.834 0.9977 3631107 CBKinase1_021128 Fc1ccccc1C(=O)c2cn(CC(=O)Nc3ccccc3)c4ccccc24 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E07 compound treatment 1921951.0 401000.0 0.68 1978484.0 249000.0 0.41 0.7684 0.9704 3631108 CBKinase1_021129 CC(=O)Nc1ccc(cc1)C(=O)CSc2nncn2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E08 compound treatment 1628135.0 107000.0 0.18 2120843.0 391000.0 0.64 0.5817 0.8727 3631109 CBKinase1_021130 Nc1nc(SCC(=O)Nc2ccccc2C(F)(F)F)[nH]c(=O)c1c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E09 mock treatment 1819395.0 298000.0 0.5 2158928.0 430000.0 0.7 0.8548 0.9867 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E10 mock treatment 2028881.0 508000.0 0.86 2182128.0 453000.0 0.74 1.1324 0.9973 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E11 compound treatment 1852530.0 331000.0 0.56 1998080.0 269000.0 0.44 0.708 0.9928 3631110 CBKinase1_021131 COc1ccc(NC(=O)c2ccc(cc2)N(C)S(=O)(=O)c3ccc(OC)c(OC)c3)c(OC)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E12 compound treatment 1863904.0 343000.0 0.58 2014758.0 285000.0 0.47 0.741 0.9943 3631111 CBKinase1_021132 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)N2CCN(C)CC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E13 compound treatment 1785017.0 264000.0 0.45 2098101.0 369000.0 0.6 0.7431 0.989 3631112 CBKinase1_021133 COc1ccc(NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C)c(OC)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E14 compound treatment 1327754.0 -193000.0 -0.33 1922550.0 193000.0 0.32 -0.0076 -0.0167 3631113 CBKinase1_021134 CCN(CC(=O)Nc1cccc(c1)[N+](=O)[O-])S(=O)(=O)c2ccc(C)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E15 compound treatment 1857797.0 337000.0 0.57 1695561.0 -33800.0 -0.06 0.3638 0.6353 3631114 CBKinase1_021135 Cc1cc(ccc1Br)N(CC(=O)NC2CCCCC2)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E16 compound treatment 1809021.0 288000.0 0.49 1930350.0 201000.0 0.33 0.5775 0.9818 3631115 CBKinase1_021136 CCN(CC(=O)Nc1ccccc1Br)S(=O)(=O)c2ccc3ccccc3c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E17 mock treatment 1951303.0 430000.0 0.73 2163350.0 434000.0 0.71 1.0178 0.9999 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E18 mock treatment 1727444.0 206000.0 0.35 2143351.0 414000.0 0.68 0.7267 0.9523 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E19 compound treatment 1498312.0 -22800.0 -0.04 1743849.0 14400.0 0.02 -0.0106 -0.233 1423647 CBKinase1_021137 CN(C)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccccc3F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E20 compound treatment 1508507.0 -12600.0 -0.02 1830019.0 101000.0 0.16 0.1015 0.6105 3631116 CBKinase1_021138 COc1ccc(NC(=O)C(C)N(c2cc(C)cc(C)c2)S(=O)(=O)C)c(OC)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E21 compound treatment 1510601.0 -10500.0 -0.02 1928588.0 199000.0 0.33 0.2182 0.6676 1394518 CBKinase1_021139 Cn1c(=O)n(C)c2nc(OCc3ccco3)n(Cc4ccc(Br)cc4)c2c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E22 compound treatment 1540708.0 19600.0 0.03 1654695.0 -74700.0 -0.12 -0.0631 -0.4976 3631117 CBKinase1_021140 CS(=O)(=O)N(CC(=O)Nc1ccc(Br)cc1)c2ccc(Cl)cc2Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E23 compound treatment 1285819.0 -235000.0 -0.4 1650561.0 -78800.0 -0.13 -0.373 -0.8908 1295904 CBKinase1_021141 Cn1c(NCc2ccco2)nc3n(C)c(=O)n(Cc4ccc(Br)cc4)c(=O)c13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 E24 compound treatment 1440480.0 -80600.0 -0.14 1540710.0 -189000.0 -0.31 -0.3152 -0.9324 3631118 CBKinase1_021142 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)Nc2cccc(Cl)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F01 mock treatment 1146171.0 -375000.0 -0.63 1574399.0 -155000.0 -0.25 -0.6284 -0.9192 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F02 mock treatment 1380303.0 -141000.0 -0.24 1846647.0 117000.0 0.19 -0.0327 -0.1067 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F03 compound treatment 1622994.0 102000.0 0.17 1992148.0 263000.0 0.43 0.4264 0.9193 3631119 CBKinase1_021143 COc1ccc(cc1N(CC(=O)N2CCOCC2)S(=O)(=O)C)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F04 compound treatment 1422397.0 -98700.0 -0.17 1715762.0 -13600.0 -0.02 -0.134 -0.7946 3631120 CBKinase1_021144 Cc1cc(CNC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc(C)c(C)c4)nn1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F05 compound treatment 1588713.0 67600.0 0.11 1635542.0 -93900.0 -0.15 -0.0279 -0.1453 3631121 CBKinase1_021145 CCOc1ccc(cc1)n2c(SCC(=O)c3ccc(Br)cc3)nnc2c4cccnc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F06 compound treatment 297498.0 -1220000.0 -2.07 323121.0 -1410000.0 -2.3 -3.0943 -0.9986 3631122 CBKinase1_021146 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=S)NCc3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F07 compound treatment 1589793.0 68700.0 0.12 1955643.0 226000.0 0.37 0.3444 0.8863 3631123 CBKinase1_021147 Cc1cccc(NC(=O)CC2Nc3cccc4cccc(NC2=O)c34)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F08 compound treatment 1790438.0 269000.0 0.46 2029213.0 300000.0 0.49 0.6698 0.9993 3631124 CBKinase1_021148 COc1cccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccc(Br)cc4)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F09 mock treatment 1836568.0 315000.0 0.53 2031125.0 302000.0 0.49 0.7272 0.9993 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F10 mock treatment 1716755.0 196000.0 0.33 1941748.0 212000.0 0.35 0.4802 0.9997 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F11 compound treatment 1840862.0 320000.0 0.54 2148409.0 419000.0 0.69 0.8683 0.9931 3631125 CBKinase1_021149 Cc1ccc2cc(ccc2c1)S(=O)(=O)NCCCC(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F12 compound treatment 1725672.0 205000.0 0.35 1939414.0 210000.0 0.34 0.4882 1.0 3631126 CBKinase1_021150 CCn1c(SCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)nnc1c3cccnc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F13 compound treatment 1799878.0 279000.0 0.47 1911281.0 182000.0 0.3 0.5444 0.9755 3119183 CBKinase1_021151 COc1ccc(cc1)N(C(=O)c2ccccc2)S(=O)(=O)c3cccc4cccnc34 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F14 compound treatment 1621940.0 101000.0 0.17 2008195.0 279000.0 0.46 0.4438 0.9098 3631127 CBKinase1_021152 Cn1c(SCC(=O)Nc2ccc(F)c(F)c2)nnc1c3ccccn3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F15 compound treatment 1734742.0 214000.0 0.36 1975165.0 246000.0 0.4 0.5405 0.9986 3631128 CBKinase1_021153 CC(NS(=O)(=O)c1ccccc1)C(=O)Nc2ccc3OCCOc3c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F16 compound treatment 1786228.0 265000.0 0.45 2044058.0 315000.0 0.52 0.682 0.9976 3631129 CBKinase1_021154 CCn1c(SCC(=O)Nc2ccc(F)cc2F)nnc1c3cccs3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F17 mock treatment 1778245.0 257000.0 0.44 1982699.0 253000.0 0.42 0.6013 0.9997 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F18 mock treatment 1683546.0 162000.0 0.27 1829770.0 100000.0 0.16 0.3107 0.9698 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F19 compound treatment 1498926.0 -22200.0 -0.04 1843774.0 114000.0 0.19 0.106 0.5544 2076247 CBKinase1_021155 Cn1c(SCC(=O)c2ccc(F)cc2)nnc1c3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F20 compound treatment 1550583.0 29500.0 0.05 1851771.0 122000.0 0.2 0.1771 0.8569 3631130 CBKinase1_021156 CC(C)(C)C(=O)CSc1ncnc2sc3CCCCc3c12 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F21 compound treatment 1591859.0 70700.0 0.12 1826905.0 97500.0 0.16 0.1977 0.9899 3631131 CBKinase1_021157 Cc1ccc(cc1)n2c(SCC(=O)Nc3cc(ccc3Cl)C(F)(F)F)nnc2c4ccco4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F22 compound treatment 1427374.0 -93700.0 -0.16 1749967.0 20600.0 0.03 -0.0884 -0.5448 3631132 CBKinase1_021158 Clc1ccc(CSc2nnc(c3ccco3)n2Cc4ccco4)c(Cl)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F23 compound treatment 1230432.0 -291000.0 -0.49 1962800.0 233000.0 0.38 -0.0774 -0.1243 3631133 CBKinase1_021159 Cc1cc(C)nc(SCC(=O)Nc2ccc(cc2)S(=O)(=O)NC(C)(C)C)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 F24 compound treatment 788575.0 -733000.0 -1.24 1513605.0 -216000.0 -0.35 -1.1269 -0.8739 3631134 CBKinase1_021160 COc1ccc(cc1)n2c(SCC(=O)Nc3cc(NC(=O)C)ccc3OC)nc4ccccc4c2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G01 compound treatment 1276487.0 -245000.0 -0.41 1429236.0 -300000.0 -0.49 -0.6407 -0.9963 3631135 CBKinase1_021161 CCn1c(SCC(=O)Nc2cccc(Br)c2)nnc1c3ccncc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G02 compound treatment 1326672.0 -194000.0 -0.33 1588832.0 -141000.0 -0.23 -0.3956 -0.9848 3631136 CBKinase1_021162 CCOC(=O)c1ccc(NC(=O)CN2C(=O)COc3ccc(Cl)cc23)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G03 mock treatment 1491533.0 -29600.0 -0.05 1621924.0 -107000.0 -0.18 -0.16 -0.8735 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G04 mock treatment 1491364.0 -29700.0 -0.05 1746155.0 16800.0 0.03 -0.0162 -0.2824 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G05 compound treatment 1470149.0 -51000.0 -0.09 1730206.0 803.0 0.0 -0.0601 -0.6962 3631137 CBKinase1_021163 Cc1nnc(SCC(=O)c2ccc(cc2)[N+](=O)[O-])s1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G06 compound treatment 1503644.0 -17500.0 -0.03 1703976.0 -25400.0 -0.04 -0.0504 -0.9859 3631138 CBKinase1_021164 Fc1ccccc1C(=O)c2cn(CC(=O)NCC3CCCO3)c4ccccc24 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G07 compound treatment 1553114.0 32000.0 0.05 1814554.0 85200.0 0.14 0.137 0.9151 3631139 CBKinase1_021165 Clc1ccccc1c2nnc(SCC(=O)c3ccc4OCCOc4c3)o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G08 compound treatment 1792633.0 272000.0 0.46 1867886.0 138000.0 0.23 0.4855 0.9471 3631140 CBKinase1_021166 Nc1nc(SCc2nc(no2)c3ccccc3)[nH]c(=O)c1c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G09 compound treatment 1702101.0 181000.0 0.31 2161123.0 432000.0 0.71 0.7169 0.9299 3631141 CBKinase1_021167 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G10 compound treatment 1831871.0 311000.0 0.53 2034920.0 306000.0 0.5 0.726 0.9997 3631142 CBKinase1_021168 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)Nc2ccc3OCCOc3c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G11 compound treatment 1673061.0 152000.0 0.26 1894156.0 165000.0 0.27 0.3728 0.9997 3631143 CBKinase1_021169 Cc1cc(ccc1Br)N(CC(=O)Nc2cccc(c2)C(F)(F)F)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G12 compound treatment 1699820.0 179000.0 0.3 2224545.0 495000.0 0.81 0.7877 0.9096 3631144 CBKinase1_021170 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)N2CCN(CC2)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G13 compound treatment 1886421.0 365000.0 0.62 2047252.0 318000.0 0.52 0.8056 0.9964 3631145 CBKinase1_021171 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)NC2CCCCC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G14 compound treatment 1755712.0 235000.0 0.4 2093166.0 364000.0 0.6 0.7023 0.9805 3631146 CBKinase1_021172 CCN(CC(=O)O)S(=O)(=O)c1ccc(Cl)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G15 compound treatment 1728153.0 207000.0 0.35 1933786.0 204000.0 0.33 0.4847 0.9997 3631147 CBKinase1_021173 Cc1cc(ccc1Br)N(CC(=O)Nc2ccc(Oc3ccccc3)cc2)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G16 compound treatment 1704645.0 184000.0 0.31 1976438.0 247000.0 0.4 0.506 0.9914 3631148 CBKinase1_021174 CCN(CC(=O)Nc1ccc(I)cc1)S(=O)(=O)c2ccc3ccccc3c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G17 compound treatment 1732150.0 211000.0 0.36 1787131.0 57700.0 0.09 0.3195 0.8646 3631149 CBKinase1_021175 CC(C)(C)C(=O)c1cn(CC(=O)Nc2ccccc2)c3ccccc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G18 compound treatment 1490658.0 -30500.0 -0.05 1870099.0 141000.0 0.23 0.1266 0.5358 3631150 CBKinase1_021176 Ic1ccc(NC(=O)CSc2nc(c3ccco3)c(C#N)c(=O)[nH]2)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G19 mock treatment 1654229.0 133000.0 0.23 1888523.0 159000.0 0.26 0.3437 0.9974 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G20 mock treatment 1393722.0 -127000.0 -0.22 1807787.0 78400.0 0.13 -0.0616 -0.2456 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G21 compound treatment 1238375.0 -283000.0 -0.48 1406626.0 -323000.0 -0.53 -0.7125 -0.9988 3631151 CBKinase1_021177 COc1ccccc1C2=NOC(Cn3c(NCc4ccccc4)nc5n(C)c(=O)n(C)c(=O)c35)C2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G22 compound treatment 1386340.0 -135000.0 -0.23 1810527.0 81100.0 0.13 -0.0673 -0.2549 3631152 CBKinase1_021178 CS(=O)(=O)N(CC(=O)Nc1cccc(Br)c1)c2ccc(F)c(Cl)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G23 compound treatment 1579623.0 58500.0 0.1 1930087.0 201000.0 0.33 0.3026 0.881 3631153 CBKinase1_021179 COCCNCCn1cnc2n(C)c(=O)[nH]c(=O)c12 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 G24 compound treatment 1445236.0 -75900.0 -0.13 1558885.0 -171000.0 -0.28 -0.2884 -0.9378 3631154 CBKinase1_021180 CCNC(=O)CN(c1ccc(Br)c(C)c1)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H01 compound treatment 1054744.0 -466000.0 -0.79 1368921.0 -360000.0 -0.59 -0.976 -0.9898 3631155 CBKinase1_021181 CS(=O)(=O)N(CC(=O)Nc1cccc2ccccc12)c3ccc(F)c(Cl)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H02 compound treatment 1367673.0 -153000.0 -0.26 1601232.0 -128000.0 -0.21 -0.3322 -0.9945 3631156 CBKinase1_021182 COc1ccccc1NC(=O)C2=C(C)Nc3ncnn3C2c4ccccc4OCc5ccccc5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H03 mock treatment 1450292.0 -70800.0 -0.12 1780821.0 51400.0 0.08 -0.0252 -0.1719 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H04 mock treatment 1422111.0 -99000.0 -0.17 1895331.0 166000.0 0.27 0.0738 0.231 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H05 compound treatment 1525676.0 4560.0 0.01 1572871.0 -157000.0 -0.26 -0.1759 -0.6855 3631157 CBKinase1_021183 COC(=O)c1c(NC(=O)C2CC(=O)NN2Cc3ccccc3)sc4CCCc14 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H06 compound treatment 1494526.0 -26600.0 -0.05 1487320.0 -242000.0 -0.4 -0.3124 -0.7823 3631158 CBKinase1_021184 CC(C)OC(=O)CSc1nnc(c2ccccc2F)n1c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H07 compound treatment 1282721.0 -238000.0 -0.4 1640966.0 -88400.0 -0.14 -0.3878 -0.9045 3631159 CBKinase1_021185 [O-][N+](=O)c1cccc(NC(=O)CC2Nc3cccc4cccc(NC2=O)c34)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H08 compound treatment 1444282.0 -76800.0 -0.13 1758542.0 29100.0 0.05 -0.0582 -0.42 3631160 CBKinase1_021186 CN(C)S(=O)(=O)c1cccc(c1)C(=O)N(Cc2ccco2)c3ccc(C)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H09 compound treatment 1588291.0 67200.0 0.11 1890704.0 161000.0 0.26 0.2673 0.929 3631161 CBKinase1_021187 COc1ccc(cc1S(=O)(=O)NCCc2ccc(F)cc2)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H10 compound treatment 1522177.0 1060.0 0.0 1721209.0 -8190.0 -0.01 -0.0082 -0.6069 3631162 CBKinase1_021188 COc1cc(cc(Br)c1O)C2N(Cc3ccco3)C(=O)c4oc5ccc(Cl)cc5c(=O)c24 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H11 compound treatment 1799542.0 278000.0 0.47 2031716.0 302000.0 0.5 0.6836 0.9997 3631163 CBKinase1_021189 Cc1ccc2cc(ccc2c1)S(=O)(=O)NCCC(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H12 compound treatment 1754354.0 233000.0 0.39 1906666.0 177000.0 0.29 0.4846 0.9886 3631164 CBKinase1_021190 CCn1c(SCC(=O)Nc2ccc3OCCOc3c2)nnc1c4cccnc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H13 compound treatment 1582350.0 61200.0 0.1 1909264.0 180000.0 0.29 0.2817 0.9016 3631165 CBKinase1_021191 COc1ccc(cc1)N(C(=O)c2cccnc2)S(=O)(=O)c3ccc4n(C)c(=O)n(C)c4c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H14 compound treatment 1531164.0 10100.0 0.02 2027967.0 299000.0 0.49 0.358 0.7312 3631166 CBKinase1_021192 Oc1ccccc1c2nnc(SC3CC(=O)N(C3=O)c4ccccc4)o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H15 compound treatment 1607648.0 86500.0 0.15 1781226.0 51800.0 0.08 0.1636 0.9664 3631167 CBKinase1_021193 COc1ccc(NC(=O)C(C)NS(=O)(=O)c2ccccc2)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H16 compound treatment 1452215.0 -68900.0 -0.12 1732310.0 2910.0 0.0 -0.0791 -0.6777 3631168 CBKinase1_021194 CCn1c(SCC(=O)Nc2cc3oc4ccccc4c3cc2OC)nnc1c5cccs5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H17 compound treatment 1543322.0 22200.0 0.04 2007507.0 278000.0 0.46 0.3489 0.7628 3631169 CBKinase1_021195 [O-][N+](=O)c1ccc(CSc2nnc(c3cnccn3)n2c4ccccc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H18 compound treatment 1203456.0 -318000.0 -0.54 1379409.0 -350000.0 -0.57 -0.7858 -0.9995 3631170 CBKinase1_021196 Cc1sc2ncnc(SCC(=O)C(C)(C)C)c2c1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H19 mock treatment 1595336.0 74200.0 0.13 1900973.0 172000.0 0.28 0.2877 0.9341 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H20 mock treatment 1236897.0 -284000.0 -0.48 1806577.0 77200.0 0.13 -0.2508 -0.5041 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H21 compound treatment 1363685.0 -157000.0 -0.27 1870045.0 141000.0 0.23 -0.0254 -0.0722 3631171 CBKinase1_021197 Cc1ccc(cc1)n2c(SCC(=O)Nc3ccc(F)c(Cl)c3)nnc2c4ccco4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H22 compound treatment 1654055.0 133000.0 0.23 1792806.0 63400.0 0.1 0.2326 0.9384 3631172 CBKinase1_021198 Fc1ccccc1CSc2nnc(c3cccnc3)n2Cc4ccco4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H23 compound treatment 1342358.0 -179000.0 -0.3 1523211.0 -206000.0 -0.34 -0.4529 -0.9985 3631173 CBKinase1_021199 CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)CSc2nc3ccccc3[nH]2)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 H24 compound treatment 1015740.0 -505000.0 -0.86 1716675.0 -12700.0 -0.02 -0.6196 -0.7241 3631174 CBKinase1_021200 COC(=O)c1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2c4ccc(Cl)cc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I01 compound treatment 1175022.0 -346000.0 -0.59 1607695.0 -122000.0 -0.2 -0.5553 -0.8973 3631175 CBKinase1_021201 CCn1c(SCC(=O)Nc2ccc(F)c(F)c2)nnc1c3ccncc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I02 compound treatment 1353119.0 -168000.0 -0.28 1770387.0 41000.0 0.07 -0.1536 -0.5256 3631176 CBKinase1_021202 CCOC(=O)c1sc2ncn(CC(=O)Nc3ccc(cc3)C(=O)C)c(=O)c2c1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I03 compound treatment 1597444.0 76300.0 0.13 1721975.0 -7430.0 -0.01 0.0828 0.6377 3631177 CBKinase1_021203 COC(=O)c1ccc(NC(=O)CSc2nnc(c3cccnc3)n2c4ccccc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I04 compound treatment 1597936.0 76800.0 0.13 1929742.0 200000.0 0.33 0.3241 0.9178 3631178 CBKinase1_021204 COc1ccc(cc1N(CC(=O)Nc2cccc(Br)c2)S(=O)(=O)C)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I05 mock treatment 1548574.0 27500.0 0.05 1906082.0 177000.0 0.29 0.2376 0.8102 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I06 mock treatment 1797185.0 276000.0 0.47 1670439.0 -59000.0 -0.1 0.2621 0.5493 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I07 compound treatment 1713193.0 192000.0 0.33 1833818.0 104000.0 0.17 0.3509 0.9551 3631179 CBKinase1_021205 Cn1cnnc1SCC(=O)c2ccc3OCCOc3c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I08 compound treatment 1418616.0 -102000.0 -0.17 1586363.0 -143000.0 -0.23 -0.2884 -0.989 3631180 CBKinase1_021206 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)NC2CC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I09 compound treatment 1632025.0 111000.0 0.19 2019670.0 290000.0 0.48 0.4691 0.9173 3631181 CBKinase1_021207 Cc1cc(ccc1Br)N(CC(=O)N)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I10 compound treatment 1667512.0 146000.0 0.25 1874241.0 145000.0 0.24 0.3431 0.9998 3631182 CBKinase1_021208 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)Nc2cccc(SC)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I11 compound treatment 1681495.0 160000.0 0.27 1921659.0 192000.0 0.32 0.4148 0.9972 3631183 CBKinase1_021209 CS(=O)(=O)N(CC(=O)Nc1ccccc1Br)c2cc(Cl)c(Cl)cc2Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I12 compound treatment 1633357.0 112000.0 0.19 1991367.0 262000.0 0.43 0.4379 0.9328 3631184 CBKinase1_021210 CCN(CC(=O)O)S(=O)(=O)c1ccc(C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I13 compound treatment 1504050.0 -17100.0 -0.03 1936876.0 207000.0 0.34 0.22 0.6447 3631185 CBKinase1_021211 CS(=O)(=O)N(CC(=O)NC1CCCC1)c2ccc(F)c(Cl)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I14 compound treatment 1433290.0 -87800.0 -0.15 1753593.0 24200.0 0.04 -0.0771 -0.501 3631186 CBKinase1_021212 CCN(CC(=O)Nc1ccccc1)S(=O)(=O)c2ccc(Cl)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I15 compound treatment 1699788.0 179000.0 0.3 1910508.0 181000.0 0.3 0.4237 1.0 3631187 CBKinase1_021213 CC(=O)c1cccc(c1)N(CC(=O)N2CCOCC2)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I16 compound treatment 1623876.0 103000.0 0.17 1875485.0 146000.0 0.24 0.2923 0.9877 3631188 CBKinase1_021214 CS(=O)(=O)N(CC(=O)O)Cc1ccc(Cl)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I17 compound treatment 1672157.0 151000.0 0.26 1932608.0 203000.0 0.33 0.4163 0.9915 3631189 CBKinase1_021215 CC(C)(C)C(=O)c1cn(CC(=O)NCc2ccco2)c3ccccc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I18 compound treatment 1740204.0 219000.0 0.37 1873398.0 144000.0 0.24 0.4291 0.9762 3631190 CBKinase1_021216 Ic1ccc(NC(=O)CSc2ncc(nn2)c3ccccc3)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I19 compound treatment 1340597.0 -181000.0 -0.31 1630844.0 -98600.0 -0.16 -0.3303 -0.9556 3121473 CBKinase1_021217 Nc1ncnc2n(CCNCc3ccccc3)cnc12 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I20 compound treatment 1609990.0 88900.0 0.15 1715196.0 -14200.0 -0.02 0.0899 0.5906 3631191 CBKinase1_021218 COc1ccc(OC)c(NC(=O)c2ccc(Cl)c(c2)S(=O)(=O)Nc3ccc(C)cc3)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I21 mock treatment 1473769.0 -47300.0 -0.08 1930102.0 201000.0 0.33 0.1759 0.5196 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I22 mock treatment 1672288.0 151000.0 0.26 1866422.0 137000.0 0.22 0.3397 0.9979 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I23 compound treatment 1621020.0 99900.0 0.17 1666643.0 -62800.0 -0.1 0.0468 0.2367 3631192 CBKinase1_021219 Cc1ccc(CN2C(CC(=O)Nc3ccccc3)C(=O)N(C2=O)c4ccccc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 I24 compound treatment 1347666.0 -173000.0 -0.29 1692195.0 -37200.0 -0.06 -0.2507 -0.8361 3631193 CBKinase1_021220 COc1ccc(cc1N(CC(=O)Nc2cccc(c2)C(F)(F)F)S(=O)(=O)C)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J01 compound treatment 1253852.0 -267000.0 -0.45 1550963.0 -178000.0 -0.29 -0.5267 -0.9777 3631194 CBKinase1_021221 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)NC2CCCCC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J02 compound treatment 1279045.0 -242000.0 -0.41 1590996.0 -138000.0 -0.23 -0.4501 -0.9611 3631195 CBKinase1_021222 CC(C)(C)c1ccc(OCC(=O)Nc2cccc3ncccc23)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J03 compound treatment 1299828.0 -221000.0 -0.37 1543569.0 -186000.0 -0.3 -0.4802 -0.9947 3631196 CBKinase1_021223 COC(=O)c1ccccc1NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J04 compound treatment 1201437.0 -320000.0 -0.54 1727804.0 -1600.0 0.0 -0.3845 -0.7105 3631197 CBKinase1_021224 Cc1sc(NC(=O)c2cc3ccccc3oc2=O)c(C(=O)NCc4cccnc4)c1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J05 mock treatment 1528453.0 7340.0 0.01 1742520.0 13100.0 0.02 0.024 0.966 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J06 mock treatment 1375949.0 -145000.0 -0.25 1451844.0 -278000.0 -0.45 -0.4954 -0.9582 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J07 compound treatment 1439704.0 -81400.0 -0.14 1952550.0 223000.0 0.37 0.1612 0.4124 3631198 CBKinase1_021225 COC(=O)c1c(NC(=O)CC2Nc3cccc4cccc(NC2=O)c34)sc5CCCCc15 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J08 compound treatment 1252711.0 -268000.0 -0.45 1484367.0 -245000.0 -0.4 -0.6052 -0.9981 3631199 CBKinase1_021226 O=C(N(Cc1ccccc1)c2ccccn2)c3cc4ccccc4oc3=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J09 compound treatment 1284339.0 -237000.0 -0.4 2029055.0 300000.0 0.49 0.0639 0.1007 3117982 CBKinase1_021227 Cn1c(=O)n(C)c2cc(ccc12)S(=O)(=O)NCCC(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J10 compound treatment 1540982.0 19900.0 0.03 2015849.0 286000.0 0.47 0.3557 0.7558 3631200 CBKinase1_021228 CCc1cccc(C)c1NC(=O)CSc2nnc(c3cccnc3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J11 compound treatment 1517035.0 -4080.0 -0.01 2050211.0 321000.0 0.53 0.3669 0.6978 3631201 CBKinase1_021229 Cc1ccc2cc(ccc2c1)S(=O)(=O)NCc3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J12 compound treatment 1469672.0 -51400.0 -0.09 1892524.0 163000.0 0.27 0.1275 0.4533 3631202 CBKinase1_021230 CCn1c(SCC(=O)Nc2cc3oc4ccccc4c3cc2OC)nnc1c5cccnc5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J13 compound treatment 1404246.0 -117000.0 -0.2 1845789.0 116000.0 0.19 -0.005 -0.0182 3631203 CBKinase1_021231 COc1ccc(cc1)N(C(=O)C)S(=O)(=O)c2cc(OC)ccc2OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J14 compound treatment 1451369.0 -69700.0 -0.12 1836111.0 107000.0 0.17 0.0402 0.1904 3631204 CBKinase1_021232 CCOC(=O)c1c(NC(=O)c2cc3cccc(OC)c3oc2=O)sc(C)c1c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J15 compound treatment 1587763.0 66600.0 0.11 2028896.0 299000.0 0.49 0.4268 0.8475 3631205 CBKinase1_021233 Cn1c(SCC(=O)Nc2c(F)cc(F)cc2Br)nnc1c3cnccn3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J16 compound treatment 1519273.0 -1840.0 0.0 1623267.0 -106000.0 -0.17 -0.1252 -0.7197 3631206 CBKinase1_021234 CCn1c(SCC(=O)Nc2cc(C)c(Cl)cc2OC)nnc1c3cccs3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J17 compound treatment 1488759.0 -32400.0 -0.05 1694549.0 -34900.0 -0.06 -0.0791 -0.9998 3631207 CBKinase1_021235 FC(F)(F)c1ccc(Cl)c(NC(=O)CSc2nnc(c3cnccn3)n2c4ccccc4)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J18 compound treatment 1452907.0 -68200.0 -0.12 1813520.0 84100.0 0.14 0.0158 0.0881 3631208 CBKinase1_021236 COc1cc(NC(=O)CSc2ncnc3sc(C)c(C)c23)cc(OC)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J19 compound treatment 1485073.0 -36000.0 -0.06 1775483.0 46100.0 0.08 0.0103 0.1057 3631209 CBKinase1_021237 CCOc1ccccc1NC(=O)CSc2nnc(c3ccco3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J20 compound treatment 1237237.0 -284000.0 -0.48 1952184.0 223000.0 0.37 -0.0816 -0.1352 3631210 CBKinase1_021238 COc1cc(NC(=O)CSc2ncnc3sc4CCCCc4c23)cc(OC)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J21 mock treatment 1526273.0 5160.0 0.01 1607680.0 -122000.0 -0.2 -0.1349 -0.6755 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J22 mock treatment 1577675.0 56600.0 0.1 1599092.0 -130000.0 -0.21 -0.0833 -0.356 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J23 compound treatment 1233107.0 -288000.0 -0.49 1476933.0 -252000.0 -0.41 -0.6373 -0.9967 3631211 CBKinase1_021239 Cc1cc(N)nc(COc2ccc(cc2)[N+](=O)[O-])n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 J24 compound treatment 929531.0 -592000.0 -1.0 1760145.0 30700.0 0.05 -0.6725 -0.6707 3631212 CBKinase1_021240 Cc1cccc(c1)c2nnc(SCc3nc4ccccc4[nH]3)n2CC=C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K01 compound treatment 1019247.0 -502000.0 -0.85 1617086.0 -112000.0 -0.18 -0.7309 -0.8408 3631213 CBKinase1_021241 CCn1c(SCC(=O)Nc2cc(Cl)ccc2Cl)nnc1c3ccncc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K02 compound treatment 1351887.0 -169000.0 -0.29 1579033.0 -150000.0 -0.25 -0.3768 -0.9972 3631214 CBKinase1_021242 Cc1cc(ccc1Br)N(CC(=O)Nc2ccccc2Cl)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K03 compound treatment 1313765.0 -207000.0 -0.35 1591576.0 -138000.0 -0.23 -0.4079 -0.9773 3631215 CBKinase1_021243 O=C(CSc1nnc(c2cccnc2)n1c3ccccc3)Nc4ccc5OCCOc5c4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K04 compound treatment 1565381.0 44300.0 0.07 1817282.0 87900.0 0.14 0.1548 0.9536 3631216 CBKinase1_021244 COC(=O)c1ccc(NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K05 compound treatment 1580457.0 59300.0 0.1 1681479.0 -47900.0 -0.08 0.0155 0.1215 3631217 CBKinase1_021245 Cn1cnnc1SCC(=O)c2ccc(cc2)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K06 compound treatment 1595561.0 74400.0 0.13 1874002.0 145000.0 0.24 0.2567 0.9563 3631218 CBKinase1_021246 O=C(Cn1ccc2ccc(C#N)cc12)NCc3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K07 mock treatment 1717819.0 197000.0 0.33 1736644.0 7240.0 0.01 0.2438 0.7318 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K08 mock treatment 1599865.0 78800.0 0.13 1842920.0 114000.0 0.19 0.2258 0.9866 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K09 compound treatment 1589915.0 68800.0 0.12 1671899.0 -57500.0 -0.09 0.0157 0.1049 3631219 CBKinase1_021247 COc1ccc(NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C)c(OC)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K10 compound treatment 1421212.0 -99900.0 -0.17 1691714.0 -37700.0 -0.06 -0.1633 -0.9068 3631220 CBKinase1_021248 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)N2CCCC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K11 compound treatment 1652604.0 131000.0 0.22 1940158.0 211000.0 0.35 0.4016 0.9774 3631221 CBKinase1_021249 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)Nc2ccc(C)cc2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K12 compound treatment 1416050.0 -105000.0 -0.18 1536701.0 -193000.0 -0.32 -0.3491 -0.9631 3631222 CBKinase1_021250 CCN(CC(=O)Nc1ccccc1)S(=O)(=O)c2ccc(C)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K13 compound treatment 1672766.0 152000.0 0.26 1795479.0 66100.0 0.11 0.2581 0.9263 3631223 CBKinase1_021251 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2ccc(Cl)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K14 compound treatment 1398228.0 -123000.0 -0.21 1487743.0 -242000.0 -0.4 -0.4271 -0.9548 3631224 CBKinase1_021252 CCN(CC(=O)Nc1cccc(c1)[N+](=O)[O-])S(=O)(=O)c2ccc(Cl)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K15 mock treatment 1696458.0 175000.0 0.3 1740178.0 10800.0 0.02 0.2224 0.7479 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K16 mock treatment 1796468.0 275000.0 0.47 1833582.0 104000.0 0.17 0.4503 0.9072 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K17 compound treatment 1357378.0 -164000.0 -0.28 1729024.0 -379.0 0.0 -0.1964 -0.7087 3631225 CBKinase1_021253 COc1ccccc1Cn2c(NCC(C)O)nc3n(C)c(=O)n(C)c(=O)c23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K18 compound treatment 1529036.0 7920.0 0.01 1843911.0 115000.0 0.19 0.1422 0.7557 3631226 CBKinase1_021254 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K19 compound treatment 1549129.0 28000.0 0.05 1750098.0 20700.0 0.03 0.0575 0.9865 3631227 CBKinase1_021255 COCc1ccccc1Cn2cnc3ccccc23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K20 compound treatment 1472606.0 -48500.0 -0.08 1678813.0 -50600.0 -0.08 -0.1167 -1.0 3631228 CBKinase1_021256 COc1ccc(OC)c(NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K21 compound treatment 1558781.0 37700.0 0.06 1885802.0 156000.0 0.26 0.2263 0.8569 1549546 CBKinase1_021257 Cn1c(NCc2ccco2)nc3n(C)c(=O)n(C)c(=O)c13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K22 compound treatment 1486890.0 -34200.0 -0.06 1919129.0 190000.0 0.31 0.1789 0.5656 3631229 CBKinase1_021258 COC(=O)c1ccccc1NC(=O)C(C)N(c2ccc(Cl)cc2)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K23 mock treatment 1497431.0 -23700.0 -0.04 1851306.0 122000.0 0.2 0.1129 0.5542 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 K24 mock treatment 1743332.0 222000.0 0.38 1727393.0 -2010.0 0.0 0.2636 0.7009 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L01 compound treatment 1033240.0 -488000.0 -0.83 1310058.0 -419000.0 -0.69 -1.0699 -0.9958 3631230 CBKinase1_021259 CS(=O)(=O)N(CC(=O)Nc1ccc(Oc2ccccc2)cc1)c3ccc(F)c(Cl)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L02 compound treatment 1249660.0 -271000.0 -0.46 1493506.0 -236000.0 -0.39 -0.5983 -0.9963 3631231 CBKinase1_021260 COC(=O)c1cc(C)sc1NC(=O)COc2ccccc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L03 compound treatment 1214819.0 -306000.0 -0.52 1404174.0 -325000.0 -0.53 -0.7435 -0.9999 3631232 CBKinase1_021261 CC(N(c1cc(C)cc(C)c1)S(=O)(=O)C)C(=O)Nc2cccc(c2)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L04 compound treatment 1340128.0 -181000.0 -0.31 1240678.0 -489000.0 -0.8 -0.783 -0.9131 3631233 CBKinase1_021262 COc1ccccc1CCNC(=O)c2cnccn2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L05 compound treatment 1238166.0 -283000.0 -0.48 1239742.0 -490000.0 -0.8 -0.9061 -0.9696 3631234 CBKinase1_021263 COc1ccc(NC(=O)CC2Nc3cccc4cccc(NC2=O)c34)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L06 compound treatment 1581391.0 60300.0 0.1 1611284.0 -118000.0 -0.19 -0.0647 -0.2958 3631235 CBKinase1_021264 Cc1cc(sc1c2ccccc2)C(=O)NCCCn3ccnc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L07 mock treatment 1494814.0 -26300.0 -0.04 1676377.0 -53000.0 -0.09 -0.0929 -0.9517 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L08 mock treatment 1493797.0 -27300.0 -0.05 1759139.0 29700.0 0.05 0.0018 0.0262 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L09 compound treatment 1575800.0 54700.0 0.09 1700553.0 -28900.0 -0.05 0.032 0.3081 3631236 CBKinase1_021265 Cn1c(=O)n(C)c2cc(ccc12)S(=O)(=O)NCc3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L10 compound treatment 1527766.0 6650.0 0.01 1648550.0 -80900.0 -0.13 -0.0857 -0.6447 3631237 CBKinase1_021266 COc1ccc(OC)c(c1)C(=O)CSc2nnc(c3cccnc3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L11 compound treatment 1438211.0 -82900.0 -0.14 1649318.0 -80100.0 -0.13 -0.192 -0.9994 3631238 CBKinase1_021267 COc1ccc(OC)c(c1)S(=O)(=O)Nc2ccc(O)c3ccccc23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L12 compound treatment 1640201.0 119000.0 0.2 1922966.0 194000.0 0.32 0.3669 0.976 3631239 CBKinase1_021268 CCn1c(SCc2cccc(OC)c2)nnc1c3cccnc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L13 compound treatment 1571649.0 50500.0 0.09 1738778.0 9370.0 0.02 0.0714 0.821 3631240 CBKinase1_021269 COc1ccc(cc1)N(C(=O)c2ccccc2)S(=O)(=O)c3cc(OC)ccc3OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L14 compound treatment 1348492.0 -173000.0 -0.29 1507376.0 -222000.0 -0.36 -0.4639 -0.9941 3631241 CBKinase1_021270 COc1cccc2cc(C(=O)N3CCN(CCN4C(=O)c5cccc6cccc(C4=O)c56)CC3)c(=O)oc12 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L15 mock treatment 1598705.0 77600.0 0.13 1707896.0 -21500.0 -0.04 0.0679 0.4997 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L16 mock treatment 1485001.0 -36100.0 -0.06 1665858.0 -63500.0 -0.1 -0.1169 -0.9678 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L17 compound treatment 1321099.0 -200000.0 -0.34 1599688.0 -130000.0 -0.21 -0.3897 -0.9749 3631242 CBKinase1_021271 O=C(CSc1nnc(c2cnccn2)n1c3ccccc3)Nc4ccc5OCCOc5c4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L18 compound treatment 921884.0 -599000.0 -1.01 893457.0 -836000.0 -1.37 -1.686 -0.9891 3631243 CBKinase1_021272 Cc1sc2ncnc(SCC(=O)Nc3cc(ccc3Cl)C(F)(F)F)c2c1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L19 compound treatment 1287697.0 -233000.0 -0.4 1393235.0 -336000.0 -0.55 -0.669 -0.9867 3631244 CBKinase1_021273 COc1ccc(OC)c(c1)C(=O)CSc2nnc(c3ccco3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L20 compound treatment 1521435.0 321.0 0.0 1703015.0 -26400.0 -0.04 -0.0302 -0.6982 3631245 CBKinase1_021274 COc1cc(NC(=O)CSc2nnc(c3ccncc3)n2C)cc(OC)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L21 compound treatment 1321844.0 -199000.0 -0.34 1548476.0 -181000.0 -0.3 -0.4482 -0.9979 3631246 CBKinase1_021275 Cc1ccc(cc1)n2c(SCC(=O)Nc3ccc4OCCOc4c3)nnc2c5ccco5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L22 compound treatment 1315753.0 -205000.0 -0.35 1371102.0 -358000.0 -0.59 -0.661 -0.9687 3631247 CBKinase1_021276 Clc1ccc(CSc2nnc(c3cccs3)n2Cc4ccco4)c(Cl)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L23 mock treatment 1383316.0 -138000.0 -0.23 1344439.0 -385000.0 -0.63 -0.6111 -0.9084 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 L24 mock treatment 1437140.0 -84000.0 -0.14 1157115.0 -572000.0 -0.94 -0.7637 -0.8051 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M01 compound treatment 932656.0 -588000.0 -1.0 1337514.0 -392000.0 -0.64 -1.1585 -0.9775 3631248 CBKinase1_021277 CCn1c(SCC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)nnc1c3ccncc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M02 compound treatment 1292172.0 -229000.0 -0.39 1635778.0 -93600.0 -0.15 -0.3825 -0.9178 3631249 CBKinase1_021278 CS(=O)(=O)N(CC(=O)Nc1ccc2ccccc2c1)c3ccc(Cl)cc3Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M03 compound treatment 1366961.0 -154000.0 -0.26 1746529.0 17100.0 0.03 -0.1647 -0.6274 3631250 CBKinase1_021279 Cc1ccc(cc1)c2nnc(SCC(=O)Nc3ccccc3C(C)(C)C)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M04 compound treatment 1262498.0 -259000.0 -0.44 1721657.0 -7750.0 -0.01 -0.3185 -0.7273 3631251 CBKinase1_021280 COC(=O)c1ccccc1NC(=O)c2ccc(Cl)c(c2)S(=O)(=O)Nc3ccc(C)cc3C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M05 compound treatment 1421459.0 -99700.0 -0.17 1651789.0 -77600.0 -0.13 -0.2092 -0.9903 3631252 CBKinase1_021281 CC(=O)Nc1ccc(cc1)C(=O)CSc2nnc(o2)c3ccccc3Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M06 compound treatment 1441992.0 -79100.0 -0.13 1810200.0 80800.0 0.13 -0.0011 -0.0057 3631253 CBKinase1_021282 Nc1nc(SCC(=O)Nc2ccccc2)[nH]c(=O)c1c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M07 compound treatment 1414251.0 -107000.0 -0.18 1549978.0 -179000.0 -0.29 -0.3358 -0.9728 3631254 CBKinase1_021283 Clc1ccccc1c2nnc(SCC(=O)c3cc4ccccc4oc3=O)o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M08 compound treatment 1366197.0 -155000.0 -0.26 1464166.0 -265000.0 -0.43 -0.4928 -0.9707 3631255 CBKinase1_021284 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)Nc2ccccc2F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M09 mock treatment 1481017.0 -40100.0 -0.07 1615373.0 -114000.0 -0.19 -0.1801 -0.906 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M10 mock treatment 1421930.0 -99200.0 -0.17 1513739.0 -216000.0 -0.35 -0.3686 -0.9421 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M11 compound treatment 1512479.0 -8630.0 -0.01 1371446.0 -358000.0 -0.59 -0.4252 -0.7245 3631256 CBKinase1_021285 CS(=O)(=O)N(CC(=O)Nc1ccc(I)cc1)c2ccc(Cl)cc2Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M12 compound treatment 1476338.0 -44800.0 -0.08 1618749.0 -111000.0 -0.18 -0.1818 -0.9251 3631257 CBKinase1_021286 CCN(CC(=O)Nc1cccc(Cl)c1C)S(=O)(=O)c2ccc(C)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M13 mock treatment 1617895.0 96800.0 0.16 1763542.0 34100.0 0.06 0.1554 0.8977 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M14 mock treatment 1429456.0 -91700.0 -0.16 1677722.0 -51700.0 -0.08 -0.1696 -0.9595 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M15 compound treatment 1433968.0 -87100.0 -0.15 1514852.0 -215000.0 -0.35 -0.3529 -0.9256 3631258 CBKinase1_021287 CC(N1c2cccc3cccc(c23)S1(=O)=O)C(=O)Nc4ccc(Oc5ccccc5)cc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M16 compound treatment 1505302.0 -15800.0 -0.03 1624168.0 -105000.0 -0.17 -0.1409 -0.8072 3631259 CBKinase1_021288 CS(=O)(=O)N(CC(=O)N)Cc1ccc(Cl)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M17 compound treatment 1322065.0 -199000.0 -0.34 1676984.0 -52400.0 -0.09 -0.299 -0.8599 1398177 CBKinase1_021289 Cn1c(=O)n(C)c2nc(NCC(O)CO)n(Cc3ccc(Cl)cc3)c2c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M18 compound treatment 1307543.0 -214000.0 -0.36 1729296.0 -107.0 0.0 -0.2558 -0.7075 3631260 CBKinase1_021290 COc1ccc(cc1N(CC(=O)Nc2ccccc2Cl)S(=O)(=O)C)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M19 compound treatment 1377268.0 -144000.0 -0.24 1937075.0 208000.0 0.34 0.0685 0.1637 1543603 CBKinase1_021291 Cc1ccccc1Cn2c(NCc3ccco3)nc4n(C)c(=O)n(C)c(=O)c24 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M20 compound treatment 1306638.0 -214000.0 -0.36 1878214.0 149000.0 0.24 -0.0843 -0.1927 3631261 CBKinase1_021292 COc1ccc(cc1N(CC(=O)N2CCCC2)S(=O)(=O)C)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M21 compound treatment 1296914.0 -224000.0 -0.38 1392898.0 -337000.0 -0.55 -0.6583 -0.9834 3631262 CBKinase1_021293 Cn1c(=O)[nH]c(=O)c2n(CCNCc3ccco3)cnc12 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M22 compound treatment 1526478.0 5360.0 0.01 1846279.0 117000.0 0.19 0.1419 0.7398 3631263 CBKinase1_021294 [O-][N+](=O)c1cccc(c1)S(=O)(=O)Nc2ccccc2C(=O)N3CCOCC3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M23 compound treatment 1387101.0 -134000.0 -0.23 1540845.0 -189000.0 -0.31 -0.3789 -0.9884 3631264 CBKinase1_021295 Cc1ccc(CN2C(CC(=O)Nc3ccc(Cl)cc3)C(=O)N(C2=O)c4ccc(F)cc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 M24 compound treatment 1563736.0 42600.0 0.07 1164466.0 -565000.0 -0.93 -0.6037 -0.65 3631265 CBKinase1_021296 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)Nc2ccccc2Br 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N01 compound treatment 828312.0 -693000.0 -1.17 1200140.0 -529000.0 -0.87 -1.4426 -0.989 3631266 CBKinase1_021297 COc1ccc(NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N02 compound treatment 938482.0 -583000.0 -0.99 1101508.0 -628000.0 -1.03 -1.425 -0.9998 3631267 CBKinase1_021298 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3csc4CCCCc34)cc2)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N03 compound treatment 910962.0 -610000.0 -1.03 1068126.0 -661000.0 -1.08 -1.4966 -0.9997 3631268 CBKinase1_021299 COc1ccccc1NC(=O)C2=C(C)NC3=C(C2c4ccc(C)o4)C(=O)CC(C3)c5ccc(OC)c(OC)c5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N04 compound treatment 1117666.0 -403000.0 -0.68 1480322.0 -249000.0 -0.41 -0.7715 -0.9697 3631269 CBKinase1_021300 CCOC(=O)Cc1csc(NC(=O)c2sc3cccc(F)c3c2Cl)n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N05 compound treatment 1021658.0 -499000.0 -0.85 1173604.0 -556000.0 -0.91 -1.2419 -0.9993 3631270 CBKinase1_021301 [O-][N+](=O)c1ccc(NC(=O)CC2Nc3cccc4cccc(NC2=O)c34)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N06 compound treatment 1224866.0 -296000.0 -0.5 1121123.0 -608000.0 -1.0 -1.0595 -0.9494 3631271 CBKinase1_021302 COc1ccc(cc1[N+](=O)[O-])C(=O)NCCCN2CCCC2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N07 compound treatment 1042499.0 -479000.0 -0.81 1662378.0 -67000.0 -0.11 -0.6505 -0.7957 3631272 CBKinase1_021303 COC(=O)c1c(C)c(C)sc1NC(=O)CC2Nc3cccc4cccc(NC2=O)c34 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N08 compound treatment 1255637.0 -265000.0 -0.45 1382719.0 -347000.0 -0.57 -0.7195 -0.9933 3631273 CBKinase1_021304 CCOc1ccccc1C(=O)Oc2c(c(C)nn2c3ccccc3)S(=O)(=O)c4ccc(C)cc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N09 mock treatment 1169868.0 -351000.0 -0.59 1344244.0 -385000.0 -0.63 -0.8668 -0.9996 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N10 mock treatment 1292619.0 -228000.0 -0.39 1254885.0 -475000.0 -0.78 -0.8234 -0.948 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N11 compound treatment 1441411.0 -79700.0 -0.13 1325758.0 -404000.0 -0.66 -0.5632 -0.8341 3631274 CBKinase1_021305 COc1ccc(cc1)N(C(=O)c2cccnc2)S(=O)(=O)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N12 compound treatment 1194751.0 -326000.0 -0.55 1352802.0 -377000.0 -0.62 -0.8271 -0.9985 3631275 CBKinase1_021306 Cn1c(SCC(=O)Nc2ccc(Br)cc2)nnc1c3ccccn3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N13 mock treatment 1460122.0 -61000.0 -0.1 1296191.0 -433000.0 -0.71 -0.575 -0.8015 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N14 mock treatment 1270782.0 -250000.0 -0.42 1412543.0 -317000.0 -0.52 -0.6668 -0.9949 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N15 compound treatment 1278966.0 -242000.0 -0.41 1173630.0 -556000.0 -0.91 -0.9339 -0.935 3631276 CBKinase1_021307 CCn1c(SCC(=O)Nc2c(C)cccc2C)nnc1c3cnccn3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N16 compound treatment 1035013.0 -486000.0 -0.82 1223162.0 -506000.0 -0.83 -1.1685 -1.0 3631277 CBKinase1_021308 CCn1c(SCC(=O)Nc2ccccc2c3ccccc3)nnc1c4cccs4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N17 compound treatment 1275806.0 -245000.0 -0.42 1373263.0 -356000.0 -0.58 -0.7063 -0.9861 3631278 CBKinase1_021309 COc1cc2c(cc1NC(=O)CSc3nnc(c4cnccn4)n3c5ccccc5)oc6ccccc62 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N18 compound treatment 1197131.0 -324000.0 -0.55 1387296.0 -342000.0 -0.56 -0.7842 -0.9999 3631279 CBKinase1_021310 Cc1sc2ncnc(SCC(=O)Nc3ccc(cc3)C(=O)N)c2c1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N19 compound treatment 1190199.0 -331000.0 -0.56 1177970.0 -551000.0 -0.9 -1.0351 -0.9735 3631280 CBKinase1_021311 C(Sc1nnc(c2ccco2)n1Cc3ccco3)c4nc5ccccc5[nH]4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N20 compound treatment 985240.0 -536000.0 -0.91 1206471.0 -523000.0 -0.86 -1.2474 -0.9996 3631281 CBKinase1_021312 Cn1c(SCC(=O)Nc2ccc(Oc3ccccc3)cc2)nnc1c4ccncc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N21 compound treatment 1063155.0 -458000.0 -0.78 1278238.0 -451000.0 -0.74 -1.071 -0.9997 3631282 CBKinase1_021313 CC(C)OC(=O)CSc1nnc(c2ccco2)n1c3ccc(C)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N22 compound treatment 1250963.0 -270000.0 -0.46 1302586.0 -427000.0 -0.7 -0.818 -0.9788 3631283 CBKinase1_021314 Fc1ccccc1CSc2nnc(c3cnccn3)n2Cc4ccco4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N23 compound treatment 903739.0 -617000.0 -1.05 1233220.0 -496000.0 -0.81 -1.314 -0.9923 3631284 CBKinase1_021315 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2cccnc2)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 N24 compound treatment 1257525.0 -264000.0 -0.45 1189134.0 -540000.0 -0.89 -0.9416 -0.9497 3631285 CBKinase1_021316 COc1ccccc1c2nnc(SCC(=O)Nc3ccccc3C(F)(F)F)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O01 compound treatment 1176498.0 -345000.0 -0.58 1057362.0 -672000.0 -1.1 -1.1913 -0.9558 3631286 CBKinase1_021317 CCn1c(SCC(=O)Nc2ccc3OCCOc3c2)nnc1c4ccncc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O02 compound treatment 1202962.0 -318000.0 -0.54 1128114.0 -601000.0 -0.99 -1.0776 -0.9596 3631287 CBKinase1_021318 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2ccccc2Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O03 compound treatment 1431335.0 -89800.0 -0.15 1361930.0 -367000.0 -0.6 -0.5333 -0.8586 3631288 CBKinase1_021319 CCn1c(SCC(=O)Nc2ccc(OC)c(Cl)c2)nnc1c3ccc(C)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O04 compound treatment 1429746.0 -91400.0 -0.15 1332738.0 -397000.0 -0.65 -0.569 -0.8516 3631289 CBKinase1_021320 CS(=O)(=O)N(CC(=O)NC1CCCCC1)c2ccc(F)c(Cl)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O05 compound treatment 1009332.0 -512000.0 -0.87 1573363.0 -156000.0 -0.26 -0.7934 -0.8784 3631290 CBKinase1_021321 CC(=O)Nc1ccc(cc1)C(=O)CSc2nnc(o2)c3cccc(Br)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O06 compound treatment 1111502.0 -410000.0 -0.69 1550143.0 -179000.0 -0.29 -0.698 -0.9269 3631291 CBKinase1_021322 Nc1nc(SCC(=O)NCC2CCCO2)[nH]c(=O)c1c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O07 compound treatment 1173617.0 -347000.0 -0.59 1208640.0 -521000.0 -0.85 -1.0194 -0.9835 3631292 CBKinase1_021323 Cn1cnnc1SCC(=O)c2cc3ccccc3oc2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O08 compound treatment 982516.0 -539000.0 -0.91 1070491.0 -659000.0 -1.08 -1.4083 -0.9965 3631293 CBKinase1_021324 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)Nc2ccc(F)c(Cl)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O09 compound treatment 1070596.0 -451000.0 -0.76 1448119.0 -281000.0 -0.46 -0.8652 -0.9709 3631294 CBKinase1_021325 COc1cccc(NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O10 compound treatment 1029231.0 -492000.0 -0.83 1391096.0 -338000.0 -0.55 -0.9808 -0.9805 3631295 CBKinase1_021326 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)N2CCCCC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O11 mock treatment 1235533.0 -286000.0 -0.48 1170087.0 -559000.0 -0.92 -0.99 -0.9553 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O12 mock treatment 911571.0 -610000.0 -1.03 1582507.0 -147000.0 -0.24 -0.8998 -0.8493 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O13 compound treatment 1168078.0 -353000.0 -0.6 1465700.0 -264000.0 -0.43 -0.7282 -0.9873 3631296 CBKinase1_021327 CC(N(c1cc(C)cc(C)c1)S(=O)(=O)C)C(=O)NC2CCCC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O14 compound treatment 1201028.0 -320000.0 -0.54 1470997.0 -258000.0 -0.42 -0.6826 -0.9926 3631297 CBKinase1_021328 CCN(CC(=O)O)S(=O)(=O)c1ccc2ccccc2c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O15 compound treatment 1094085.0 -427000.0 -0.72 1398733.0 -331000.0 -0.54 -0.8943 -0.9899 3631298 CBKinase1_021329 CC(=O)c1cn(CC(=O)NCc2cccnc2)c3ccccc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O16 compound treatment 1133813.0 -387000.0 -0.66 1114993.0 -614000.0 -1.01 -1.1756 -0.9784 3631299 CBKinase1_021330 CS(=O)(=O)N(CC(=O)Nc1ccccc1)Cc2ccc(Cl)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O17 compound treatment 1085418.0 -436000.0 -0.74 1310274.0 -419000.0 -0.69 -1.0072 -0.9994 1311890 CBKinase1_021331 CN(C)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccccc3Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O18 compound treatment 1071327.0 -450000.0 -0.76 1389185.0 -340000.0 -0.56 -0.9326 -0.9883 3631300 CBKinase1_021332 Cc1ccc(cc1)N(CC(=O)N)S(=O)(=O)c2ccc(Cl)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O19 compound treatment 1515546.0 -5570.0 -0.01 1431307.0 -298000.0 -0.49 -0.3521 -0.7206 1443154 CBKinase1_021333 Cn1c(NCCO)nc2n(C)c(=O)n(Cc3ccccc3Cl)c(=O)c12 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O20 compound treatment 1084932.0 -436000.0 -0.74 1288329.0 -441000.0 -0.72 -1.0332 -0.9999 3631301 CBKinase1_021334 CC(=O)c1cccc(c1)N(CC(=O)Nc2c(C)cccc2C)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O21 compound treatment 1058144.0 -463000.0 -0.78 1579511.0 -150000.0 -0.25 -0.7278 -0.8862 3631302 CBKinase1_021335 Clc1cccc(Cl)c1Cn2cnc3c(Oc4cccnc4)ncnc23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O22 compound treatment 1574422.0 53300.0 0.09 1566742.0 -163000.0 -0.27 -0.1247 -0.4431 3631303 CBKinase1_021336 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2ccc(Oc3ccccc3)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O23 compound treatment 1533137.0 12000.0 0.02 1590307.0 -139000.0 -0.23 -0.1468 -0.6414 3631304 CBKinase1_021337 Fc1ccc(cc1)N2C(=O)C(CC(=O)Nc3ccccc3)N(Cc4ccccn4)C2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 O24 compound treatment 1464011.0 -57100.0 -0.1 1385318.0 -344000.0 -0.56 -0.4671 -0.8164 3631305 CBKinase1_021338 COc1ccc(cc1N(CC(=O)N2CCCCC2)S(=O)(=O)C)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P01 compound treatment 804402.0 -717000.0 -1.21 938428.0 -791000.0 -1.3 -1.7745 -0.9995 3631306 CBKinase1_021339 CC(N(c1cc(C)cc(C)c1)S(=O)(=O)C)C(=O)Nc2cccc(Br)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P02 compound treatment 969433.0 -552000.0 -0.93 1143350.0 -586000.0 -0.96 -1.3395 -0.9999 3631307 CBKinase1_021340 COC(=O)c1cc(OC)c(OC)cc1NC(=O)C2c3ccccc3Oc4ccccc24 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P03 compound treatment 1167164.0 -354000.0 -0.6 1252398.0 -477000.0 -0.78 -0.9764 -0.9914 3631308 CBKinase1_021341 COc1ccccc1NC(=O)C(CCS(=O)(=O)C)N2C(=O)c3ccc(Br)cc3C2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P04 compound treatment 1151592.0 -370000.0 -0.63 1136635.0 -593000.0 -0.97 -1.1292 -0.9773 3631309 CBKinase1_021342 COC(=O)c1c(NC(=O)COc2ccccc2)scc1c3ccc(OC)c(OC)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P05 compound treatment 1111149.0 -410000.0 -0.69 1296505.0 -433000.0 -0.71 -0.9924 -0.9999 3631310 CBKinase1_021343 CC(=O)c1ccc(NC(=O)CC2Nc3cccc4cccc(NC2=O)c34)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P06 compound treatment 1302190.0 -219000.0 -0.37 1303027.0 -426000.0 -0.7 -0.7561 -0.956 3631311 CBKinase1_021344 Cc1onc(c1C(=O)Nc2cccc(Cn3cccn3)c2)c4c(F)cccc4Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P07 compound treatment 864940.0 -656000.0 -1.11 1270355.0 -459000.0 -0.75 -1.3174 -0.982 3631312 CBKinase1_021345 CCc1cc(C(=O)OC)c(NC(=O)CC2Nc3cccc4cccc(NC2=O)c34)s1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P08 compound treatment 1090047.0 -431000.0 -0.73 1241450.0 -488000.0 -0.8 -1.0814 -0.999 3631313 CBKinase1_021346 Cc1nn(c(OC(=O)c2ccccc2Br)c1S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P09 compound treatment 1113661.0 -407000.0 -0.69 1435479.0 -294000.0 -0.48 -0.8283 -0.9846 3631314 CBKinase1_021347 Cn1c(=O)oc2cc(ccc12)S(=O)(=O)NCCC(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P10 compound treatment 1249843.0 -271000.0 -0.46 1209307.0 -520000.0 -0.85 -0.9274 -0.9579 3631315 CBKinase1_021348 Cn1c(SCC(=O)c2ccc(cc2)[N+](=O)[O-])nnc1c3cccnc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P11 mock treatment 1342612.0 -179000.0 -0.3 1409797.0 -320000.0 -0.52 -0.584 -0.9658 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P12 mock treatment 1156543.0 -365000.0 -0.62 1670820.0 -58600.0 -0.1 -0.5043 -0.8074 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P13 compound treatment 1040017.0 -481000.0 -0.81 1193038.0 -536000.0 -0.88 -1.1974 -0.9993 3631316 CBKinase1_021349 COc1ccc(cc1)N(C(=O)C2CCCCC2)S(=O)(=O)c3cc(OC)ccc3OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P14 compound treatment 972802.0 -548000.0 -0.93 1257586.0 -472000.0 -0.77 -1.2031 -0.9959 3631317 CBKinase1_021350 CCn1c(SCC(=O)c2ccc(OC)cc2)nnc1c3cccs3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P15 compound treatment 1349440.0 -172000.0 -0.29 1330103.0 -399000.0 -0.65 -0.6682 -0.9332 3631318 CBKinase1_021351 CCn1c(SCC(=O)Nc2cc(C)c(Cl)cc2OC)nnc1c3cnccn3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P16 compound treatment 1136169.0 -385000.0 -0.65 1329173.0 -400000.0 -0.66 -0.9246 -1.0 3631319 CBKinase1_021352 CCn1c(SCC(=O)Nc2ccc3OCCOc3c2)nnc1c4ccco4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P17 compound treatment 1296347.0 -225000.0 -0.38 1200988.0 -528000.0 -0.87 -0.8814 -0.9318 3631320 CBKinase1_021353 C(Sc1nnc(c2cnccn2)n1c3ccccc3)c4nc5ccccc5[nH]4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P18 compound treatment 838279.0 -683000.0 -1.16 1171654.0 -558000.0 -0.91 -1.4637 -0.9932 3631321 CBKinase1_021354 CCN(CC)C(=O)CSc1ncnc2sc(C)c(C)c12 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P19 compound treatment 1433424.0 -87700.0 -0.15 1431729.0 -298000.0 -0.49 -0.4499 -0.8823 3631322 CBKinase1_021355 Cc1ccc(cc1)n2c(SCC(=O)Nc3ccc(Br)cc3)nnc2c4ccco4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P20 compound treatment 1056135.0 -465000.0 -0.79 1460531.0 -269000.0 -0.44 -0.8681 -0.9624 3631323 CBKinase1_021356 COc1cc(Cl)c(C)cc1NC(=O)CSc2nnc(c3ccncc3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P21 compound treatment 1459386.0 -61700.0 -0.1 1346318.0 -383000.0 -0.63 -0.5178 -0.8136 3631324 CBKinase1_021357 NC(=O)CSc1nnc(c2ccncc2)n1c3cccc(c3)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P22 compound treatment 1462584.0 -58500.0 -0.1 1115354.0 -614000.0 -1.01 -0.7817 -0.773 3631325 CBKinase1_021358 Fc1ccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccc(Cl)cc4)c(F)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P23 compound treatment 1255767.0 -265000.0 -0.45 1374328.0 -355000.0 -0.58 -0.7291 -0.9918 3631326 CBKinase1_021359 COc1ccc(OC)c(c1)S(=O)(=O)N(C)c2ccccc2C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2390 P24 compound treatment 1143893.0 -377000.0 -0.64 1140952.0 -588000.0 -0.96 -1.1334 -0.98 3631327 CBKinase1_021360 COc1ccccc1c2nnc(SCC(=O)Nc3ccccc3c4ccccc4)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A01 compound treatment 1087195.0 -566000.0 -0.96 1048024.0 -883000.0 -1.45 -1.7006 -0.98 3631328 CBKinase1_021361 CCn1c(SCC(=O)Nc2ccc(F)cc2F)nnc1c3ccccc3OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A02 compound treatment 1459000.0 -194000.0 -0.33 1312095.0 -619000.0 -1.01 -0.9495 -0.8909 3631329 CBKinase1_021362 Cc1ccc(NS(=O)(=O)c2ccc(OCC(=O)O)cc2)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A03 compound treatment 1366098.0 -287000.0 -0.49 1472868.0 -458000.0 -0.75 -0.8744 -0.978 3631330 CBKinase1_021363 COc1ccc(CCNC(=O)Nc2cccc(c2)[N+](=O)[O-])cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A04 compound treatment 1486450.0 -167000.0 -0.28 1266700.0 -664000.0 -1.09 -0.9693 -0.8622 3631331 CBKinase1_021364 COc1ccc(Cl)cc1NC(=O)C(C)NS(=O)(=O)c2ccc(Br)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A05 compound treatment 1448887.0 -205000.0 -0.35 1361192.0 -569000.0 -0.93 -0.9047 -0.9089 3631332 CBKinase1_021365 OC(=O)CCC(=O)N1N=C(CC1c2ccccn2)c3c(O)nc4ccc(Cl)cc4c3c5ccccc5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A06 compound treatment 1382437.0 -271000.0 -0.46 1628625.0 -302000.0 -0.49 -0.6744 -0.9993 3631333 CBKinase1_021366 CSc1ccccc1NC(=O)C(C)NS(=O)(=O)c2ccccc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A07 compound treatment 1085119.0 -568000.0 -0.96 1315332.0 -615000.0 -1.01 -1.3933 -0.9997 3631334 CBKinase1_021367 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2ccccc2C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A08 compound treatment 1593217.0 -60200.0 -0.1 1666684.0 -264000.0 -0.43 -0.378 -0.8504 3631335 CBKinase1_021368 CNC(=O)CN(c1ccc(C)cc1)S(=O)(=O)c2ccc(Cl)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A09 compound treatment 1567124.0 -86300.0 -0.15 1982269.0 51600.0 0.08 -0.0435 -0.2575 3631336 CBKinase1_021369 Fc1cccc(NC(=O)CSc2nnc(o2)c3cccc4ccccc34)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A10 compound treatment 1417501.0 -236000.0 -0.4 1852429.0 -78200.0 -0.13 -0.373 -0.8894 3631337 CBKinase1_021370 [O-][N+](=O)c1cccc(c1)C(=O)CSc2nnc(o2)c3ccc(Cl)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A11 compound treatment 1450305.0 -203000.0 -0.34 1731320.0 -199000.0 -0.33 -0.4741 -0.9997 3631338 CBKinase1_021371 COc1ccc(OC)c(c1)S(=O)(=O)N(C)CC(=O)N2CCOCC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A12 compound treatment 941150.0 -712000.0 -1.21 1598723.0 -332000.0 -0.54 -1.2372 -0.9353 1986264 CBKinase1_021372 CCC(=O)c1cn(CC(=O)O)c2ccccc12 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A13 mock treatment 1583180.0 -70200.0 -0.12 1924006.0 -6640.0 -0.01 -0.0918 -0.7686 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A14 mock treatment 1441929.0 -211000.0 -0.36 1688671.0 -242000.0 -0.4 -0.5336 -0.9987 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A15 compound treatment 1681927.0 28500.0 0.05 1758130.0 -173000.0 -0.28 -0.1658 -0.5781 3631339 CBKinase1_021373 O=C(Cn1cnc2ccccc2c1=O)Nc3ccc(cc3)S(=O)(=O)N4CCCC4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A16 compound treatment 1631512.0 -21900.0 -0.04 2138635.0 208000.0 0.34 0.2148 0.6265 3631340 CBKinase1_021374 Clc1cccc(NC(=O)CSc2nnc([nH]2)c3ccncc3)c1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A17 compound treatment 1538270.0 -115000.0 -0.19 2124953.0 194000.0 0.32 0.0873 0.2339 3631341 CBKinase1_021375 O=C(CCn1cnc2ccccc2c1=O)Nc3ccc(cc3)S(=O)(=O)N4CCCC4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A18 compound treatment 1412854.0 -241000.0 -0.41 1407243.0 -523000.0 -0.86 -0.8945 -0.942 1864416 CBKinase1_021376 [O-][N+](=O)c1cccc(c1)C(=O)CSc2nnc(o2)c3ccncc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A19 compound treatment 1565614.0 -87800.0 -0.15 1407119.0 -524000.0 -0.86 -0.7118 -0.8174 3631342 CBKinase1_021377 CCOC(=O)c1c(NC(=O)Cn2c(=O)oc3cc(Br)ccc23)sc4CCCCc14 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A20 compound treatment 1501157.0 -152000.0 -0.26 1278999.0 -652000.0 -1.07 -0.9374 -0.8533 3211493 CBKinase1_021378 COc1cccc(Cn2c(nc3ccccc23)c4cncs4)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A21 compound treatment 1211351.0 -442000.0 -0.75 1508814.0 -422000.0 -0.69 -1.018 -0.9992 3631343 CBKinase1_021379 FC(F)(F)c1nc(SCC(=O)Nc2ccc(Cl)cc2)nc-3c1CCc4ccccc43 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A22 compound treatment 1466453.0 -187000.0 -0.32 1462566.0 -468000.0 -0.77 -0.7662 -0.9233 3631344 CBKinase1_021380 COc1ccc(cc1)c2cc(C(F)F)n3ncc(C(=O)Nc4cccc(c4)S(=O)(=O)N5CCOCC5)c3n2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A23 compound treatment 1548260.0 -105000.0 -0.18 1360840.0 -570000.0 -0.93 -0.7862 -0.827 3631345 CBKinase1_021381 CC(=O)NC(=S)Nc1ccc(cc1)S(=O)(=O)Nc2nc(C)cc(C)n2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 A24 compound treatment 1217119.0 -436000.0 -0.74 1473519.0 -457000.0 -0.75 -1.052 -1.0 3631346 CBKinase1_021382 COc1cc(NC(=O)CN2c3cccc4cccc(c34)S2(=O)=O)cc(OC)c1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B01 compound treatment 1096557.0 -557000.0 -0.94 1330665.0 -600000.0 -0.98 -1.3618 -0.9998 3631347 CBKinase1_021383 CCN1CCN(CC1)C(=O)CSc2nc(cc(n2)C(F)(F)F)c3ccc(OC)c(OC)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B02 compound treatment 1495368.0 -158000.0 -0.27 1857911.0 -72700.0 -0.12 -0.2735 -0.9337 3631348 CBKinase1_021384 CCn1c(SCC(=O)Nc2ccc3OCCOc3c2)nc4sc(C)c(C)c4c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B03 compound treatment 1501962.0 -151000.0 -0.26 1958824.0 28200.0 0.05 -0.1486 -0.5706 1788885 CBKinase1_021385 CCOC(=O)c1c(NC(=O)c2nc3ncccn3n2)sc4CC(C)CCc14 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B04 compound treatment 1672190.0 18800.0 0.03 1747856.0 -183000.0 -0.3 -0.1894 -0.6286 3631349 CBKinase1_021386 Fc1ccccc1c2nnc(SCc3nc4ccccc4[nH]3)n2c5ccccc5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B05 compound treatment 1446047.0 -207000.0 -0.35 2070480.0 140000.0 0.23 -0.0862 -0.2055 3631350 CBKinase1_021387 COc1ccc(cc1OC)c2cc(nc(SCC(=O)N(C)c3ccccc3)n2)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B06 compound treatment 1437846.0 -216000.0 -0.36 2074948.0 144000.0 0.24 -0.0908 -0.2088 3631351 CBKinase1_021388 COc1ccc(NC(=O)C2CC=CCC2C(=O)Nc3ccccc3Cl)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B07 compound treatment 1466582.0 -187000.0 -0.32 2049448.0 119000.0 0.19 -0.086 -0.2314 3631352 CBKinase1_021389 [O-][N+](=O)c1ccccc1OCC(=O)Nc2cccc3ncccc23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B08 compound treatment 1705599.0 52200.0 0.09 2088763.0 158000.0 0.26 0.2457 0.8974 3631353 CBKinase1_021390 Cn1c(SCC(=O)Nc2ccccc2c3ccccc3)nnc1c4ccccn4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B09 compound treatment 1674365.0 20900.0 0.04 1730805.0 -200000.0 -0.33 -0.2065 -0.6269 3631354 CBKinase1_021391 Cc1ccc(OCC(=O)Nc2cc(Cl)ccc2N3CCOCC3)c(C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B10 compound treatment 1479604.0 -174000.0 -0.29 2003890.0 73200.0 0.12 -0.1232 -0.3876 3631355 CBKinase1_021392 O=C(CSc1nnc(c2ccccn2)n1c3ccccc3)Nc4ccc5cn[nH]c5c4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B11 compound treatment 1738523.0 85100.0 0.14 2227944.0 297000.0 0.49 0.4464 0.8786 3631356 CBKinase1_021393 Cc1ccccc1OCC(=O)NC(=S)Nc2ccccc2N3CCN(CC3)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B12 compound treatment 1559151.0 -94300.0 -0.16 2101741.0 171000.0 0.28 0.0854 0.2648 3631357 CBKinase1_021394 Cn1c(SCc2nc3ccccc3[nH]2)nnc1c4cnccn4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B13 mock treatment 1651651.0 -1770.0 0.0 2216742.0 286000.0 0.47 0.3294 0.7026 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B14 mock treatment 1700407.0 47000.0 0.08 1790967.0 -140000.0 -0.23 -0.1056 -0.4359 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B15 compound treatment 1875699.0 222000.0 0.38 2298589.0 368000.0 0.6 0.6924 0.9742 3631358 CBKinase1_021395 O=C(COc1ccc(cc1)C(=O)NC2CCCCC2)Nc3sc4CCCc4c3C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B16 compound treatment 1862069.0 209000.0 0.35 2269682.0 339000.0 0.56 0.6426 0.9761 3631359 CBKinase1_021396 Cc1ccnc(SCC(=O)c2cccc(c2)[N+](=O)[O-])n1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B17 compound treatment 1704320.0 50900.0 0.09 2427864.0 497000.0 0.81 0.6371 0.7775 3631360 CBKinase1_021397 COc1ccc(NC(=O)CSc2ncnc3sc4CC(C)CCc4c23)c(c1)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B18 compound treatment 1866463.0 213000.0 0.36 2458310.0 528000.0 0.86 0.8665 0.9248 3631361 CBKinase1_021398 COC(=O)c1ccc(NC(=O)C(C)N2c3cccc4cccc(c34)S2(=O)=O)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B19 compound treatment 1614575.0 -38800.0 -0.07 1919039.0 -11600.0 -0.02 -0.0599 -0.8757 3631362 CBKinase1_021399 FC(F)(F)c1ccccc1NC(=O)CSc2ncnc3sc(cc23)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B20 compound treatment 1386635.0 -267000.0 -0.45 1941595.0 10900.0 0.02 -0.3066 -0.6785 3631363 CBKinase1_021400 Cc1nc(SCC(=O)Nc2ccc(F)cc2)nc3CCCCc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B21 compound treatment 1488330.0 -165000.0 -0.28 1838127.0 -92500.0 -0.15 -0.3048 -0.9587 2069069 CBKinase1_021401 OC(=O)CSc1nnc(c2cccs2)n1c3cccc(c3)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B22 compound treatment 1373994.0 -279000.0 -0.47 1555924.0 -375000.0 -0.61 -0.7687 -0.9917 3631364 CBKinase1_021402 CC(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccc(cc2)C(=O)N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B23 compound treatment 1650606.0 -2820.0 0.0 1772219.0 -158000.0 -0.26 -0.187 -0.72 3631365 CBKinase1_021403 Cc1ccc(Cl)cc1NC(=O)CSc2nnc(c3cccs3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 B24 compound treatment 1257517.0 -396000.0 -0.67 1676196.0 -254000.0 -0.42 -0.7687 -0.9739 3631366 CBKinase1_021404 COC(=O)c1ccc(NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C01 compound treatment 1449133.0 -204000.0 -0.35 1545134.0 -386000.0 -0.63 -0.6913 -0.9598 3631367 CBKinase1_021405 CCn1c(SCC(=O)Nc2cc(Cl)ccc2Cl)nnc1c3ccccc3OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C02 compound treatment 1898350.0 245000.0 0.41 1920845.0 -9800.0 -0.02 0.2818 0.6792 3631368 CBKinase1_021406 Clc1cc(ccc1OCC(=O)N2CCOCC2)S(=O)(=O)NC3CCCCC3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C03 compound treatment 1879997.0 227000.0 0.38 2160153.0 230000.0 0.38 0.5372 1.0 3631369 CBKinase1_021407 COc1cc(OC)cc(OCC(O)Cn2cnc3ccccc23)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C04 compound treatment 2066781.0 413000.0 0.7 2114250.0 184000.0 0.3 0.7075 0.9289 3631370 CBKinase1_021408 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3ccccc3F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C05 compound treatment 1780454.0 127000.0 0.22 1885988.0 -44700.0 -0.07 0.1003 0.4416 3631371 CBKinase1_021409 Clc1ccc2[nH]c(=O)c(C3=NN(C(C3)c4ccco4)C(=O)C5CCCO5)c(c6ccccc6)c2c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C06 compound treatment 1964773.0 311000.0 0.53 2082390.0 152000.0 0.25 0.5485 0.9412 3631372 CBKinase1_021410 CC(NS(=O)(=O)c1ccccc1)C(=O)Nc2ccccc2Sc3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C07 compound treatment 2039960.0 387000.0 0.65 2472595.0 542000.0 0.89 1.0907 0.9887 3631373 CBKinase1_021411 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2ccccc2OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C08 compound treatment 1979361.0 326000.0 0.55 2028461.0 97800.0 0.16 0.5035 0.8763 3631374 CBKinase1_021412 Cc1ccc(cc1NC(=O)C2CCCN(C2)S(=O)(=O)c3ccc(F)cc3)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C09 compound treatment 1913306.0 260000.0 0.44 2217269.0 287000.0 0.47 0.6432 0.9995 3631375 CBKinase1_021413 COc1ccc(OC)c(c1)S(=O)(=O)N(C)CC(=O)Nc2ccccc2F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C10 compound treatment 2042070.0 389000.0 0.66 2533694.0 603000.0 0.99 1.164 0.9804 3631376 CBKinase1_021414 COc1cc(OC)cc(c1)c2nnc(SCC(=O)Nc3sc4CC(CCc4c3C#N)C(C)(C)C)o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C11 mock treatment 2035901.0 382000.0 0.65 2484102.0 553000.0 0.91 1.0992 0.9863 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C12 mock treatment 1778494.0 125000.0 0.21 2270340.0 340000.0 0.56 0.5434 0.9123 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C13 compound treatment 2017954.0 365000.0 0.62 2253511.0 323000.0 0.53 0.8105 0.9971 3631377 CBKinase1_021415 O=C(Cn1c(=O)oc2ccccc12)Nc3ccc(cc3)S(=O)(=O)N4CCOCC4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C14 compound treatment 2093459.0 440000.0 0.74 2401389.0 471000.0 0.77 1.0722 0.9998 3631378 CBKinase1_021416 CNC(=O)CN(c1ccccc1)S(=O)(=O)c2ccc(F)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C15 mock treatment 1879920.0 226000.0 0.38 2504619.0 574000.0 0.94 0.9363 0.9217 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C16 mock treatment 1947940.0 295000.0 0.5 2534845.0 604000.0 0.99 1.0527 0.9496 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C17 compound treatment 2286899.0 633000.0 1.07 2284212.0 354000.0 0.58 1.168 0.9583 1625307 CBKinase1_021417 COc1ccc(NC(=O)Cn2cnc3ccccc3c2=O)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C18 compound treatment 1888029.0 235000.0 0.4 2232179.0 302000.0 0.49 0.6302 0.9941 3631379 CBKinase1_021418 CS(=O)(=O)N(CC(=O)Nc1ccccc1)c2ccc(F)c(Cl)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C19 compound treatment 2111432.0 458000.0 0.78 2295822.0 365000.0 0.6 0.9714 0.9918 1624945 CBKinase1_021419 Cc1cc(Br)ccc1NC(=O)Cn2cnc3ccccc3c2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C20 compound treatment 2290554.0 637000.0 1.08 2429544.0 499000.0 0.82 1.3408 0.9907 3631380 CBKinase1_021420 CCOC(=O)c1ccc(NC(=O)CSc2nc3cc(C)ccc3[nH]2)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C21 compound treatment 1746009.0 92600.0 0.16 1734931.0 -196000.0 -0.32 -0.116 -0.3249 3631381 CBKinase1_021421 Cc1c(NC(=O)CSc2nc(c3CCc4ccccc4-c3n2)C(F)(F)F)c(=O)n(c5ccccc5)n1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C22 compound treatment 1692595.0 39200.0 0.07 2197602.0 267000.0 0.44 0.3563 0.8051 3631382 CBKinase1_021422 OCCc1cnc2cc(nn2c1)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C23 compound treatment 1943507.0 290000.0 0.49 2064440.0 134000.0 0.22 0.5023 0.934 3631383 CBKinase1_021423 Cc1c(Cl)c(nn1CC(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 C24 compound treatment 1626552.0 -26900.0 -0.05 1873618.0 -57000.0 -0.09 -0.0983 -0.9452 1788889 CBKinase1_021424 Cc1ccccc1Cn2cc(NC(=O)c3nc4ncccn4n3)cn2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D01 compound treatment 1479883.0 -174000.0 -0.29 1534168.0 -396000.0 -0.65 -0.6672 -0.9356 1788834 CBKinase1_021425 O=C(NCc1ccco1)c2nc3ncccn3n2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D02 compound treatment 1687958.0 34500.0 0.06 1557342.0 -373000.0 -0.61 -0.3913 -0.6366 3631384 CBKinase1_021426 CCn1c(SCc2nc3ccccc3[nH]2)nc4sc(C)c(C)c4c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D03 compound treatment 1762173.0 109000.0 0.18 1777672.0 -153000.0 -0.25 -0.0471 -0.1515 3631385 CBKinase1_021427 FC(F)(F)c1cc(nc(SCCC(=O)Nc2cccnc2)n1)c3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D04 compound treatment 1920395.0 267000.0 0.45 2188719.0 258000.0 0.42 0.6186 0.9995 3631386 CBKinase1_021428 NS(=O)(=O)c1ccc(NC(=O)CSc2nnc(c3ccccc3F)n2c4ccccc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D05 compound treatment 1893798.0 240000.0 0.41 2133132.0 202000.0 0.33 0.5224 0.9949 3026939 CBKinase1_021429 COc1ccc(cc1OC)c2cc(nc(SCC(=O)N3CCc4ccccc34)n2)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D06 compound treatment 1907168.0 254000.0 0.43 2132177.0 202000.0 0.33 0.5373 0.9916 3631387 CBKinase1_021430 CN(CC(=O)O)S(=O)(=O)c1ccc(NC(=O)C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D07 compound treatment 1987742.0 334000.0 0.57 2359475.0 429000.0 0.7 0.8971 0.9942 3631388 CBKinase1_021431 [O-][N+](=O)c1ccc(OCC(=O)Nc2cccc3cccnc23)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D08 compound treatment 1998440.0 345000.0 0.58 2309340.0 379000.0 0.62 0.8518 0.9995 3631389 CBKinase1_021432 Cn1c(SCc2nc3ccccc3[nH]2)nnc1c4ccccn4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D09 compound treatment 2048049.0 395000.0 0.67 2905387.0 975000.0 1.6 1.6019 0.9252 3631390 CBKinase1_021433 O=C(COc1ccc(cc1)C2CCCCC2)Nc3cccc4ncccc34 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D10 compound treatment 1933484.0 280000.0 0.47 2171232.0 241000.0 0.39 0.614 0.9958 3631391 CBKinase1_021434 Cc1ccc(cc1)n2c(SCC(=O)Nc3ccc(F)c(F)c3)nnc2c4ccccn4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D11 mock treatment 1958721.0 305000.0 0.52 2351804.0 421000.0 0.69 0.8535 0.9898 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D12 mock treatment 1961882.0 308000.0 0.52 2559872.0 629000.0 1.03 1.0984 0.9503 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D13 compound treatment 2002155.0 349000.0 0.59 2329674.0 399000.0 0.65 0.8798 0.9987 3631392 CBKinase1_021435 OCc1cc(Br)ccc1OCC(=O)Nc2ccc(F)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D14 compound treatment 1715615.0 62200.0 0.11 2238345.0 308000.0 0.5 0.431 0.8367 3631393 CBKinase1_021436 COc1cc(OC)cc(c1)c2nnc(SCC(=O)c3cccc(c3)[N+](=O)[O-])o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D15 mock treatment 1898675.0 245000.0 0.42 2309342.0 379000.0 0.62 0.7324 0.9809 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D16 mock treatment 1988202.0 335000.0 0.57 2250884.0 320000.0 0.52 0.7718 0.9993 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D17 compound treatment 1783499.0 130000.0 0.22 2067789.0 137000.0 0.22 0.3146 0.9999 3631394 CBKinase1_021437 CC1CCc2c(C1)sc3ncnc(SCC(=O)Nc4cccc(Cl)c4Cl)c23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D18 compound treatment 1786889.0 133000.0 0.23 2212280.0 282000.0 0.46 0.4861 0.946 3631395 CBKinase1_021438 COC(=O)c1ccccc1NC(=O)C(C)NS(=O)(=O)c2ccc(F)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D19 compound treatment 1847542.0 194000.0 0.33 2246973.0 316000.0 0.52 0.5989 0.9758 3631396 CBKinase1_021439 COc1ccc(NC(=O)CSc2ncnc3sc(cc23)c4ccccc4)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D20 compound treatment 1783355.0 130000.0 0.22 2088753.0 158000.0 0.26 0.3387 0.9967 3119941 CBKinase1_021440 O=C(Cn1cc(C(=O)c2ccco2)c3ccccc13)NCC4CCCO4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D21 compound treatment 1834868.0 181000.0 0.31 2076803.0 146000.0 0.24 0.3866 0.9924 3631397 CBKinase1_021441 CCOC(=O)c1c(NC(=O)c2ccc(C)c(c2)S(=O)(=O)N3CCCCCC3)sc4CCCc14 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D22 compound treatment 1881162.0 228000.0 0.39 2161362.0 231000.0 0.38 0.54 1.0 3631398 CBKinase1_021442 COc1ccc(NC(=O)CN(c2ccc(Cl)cc2Cl)S(=O)(=O)C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D23 compound treatment 1832460.0 179000.0 0.3 1851852.0 -78800.0 -0.13 0.123 0.3733 3631399 CBKinase1_021443 Cn1c(SCC(=O)Nc2cccc(Br)c2)nnc1c3cccs3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 D24 compound treatment 1773235.0 120000.0 0.2 1920357.0 -10300.0 -0.02 0.1315 0.6461 3631400 CBKinase1_021444 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2cccc(Br)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E01 mock treatment 1373821.0 -280000.0 -0.47 1643341.0 -287000.0 -0.47 -0.6676 -1.0 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E02 mock treatment 1828174.0 175000.0 0.3 1796481.0 -134000.0 -0.22 0.0537 0.1457 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E03 compound treatment 1826565.0 173000.0 0.29 2157373.0 227000.0 0.37 0.47 0.9931 3087253 CBKinase1_021445 COc1cc(OC)cc(OCC(O)Cn2ccnc2)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E04 compound treatment 1453840.0 -200000.0 -0.34 1572165.0 -358000.0 -0.59 -0.6543 -0.9655 3631401 CBKinase1_021446 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3ccc(Cl)c(c3)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E05 compound treatment 1015163.0 -638000.0 -1.08 1098230.0 -832000.0 -1.36 -1.7286 -0.9933 1972738 CBKinase1_021447 CN1CCN(CC(=O)N2N=C(CC2c3ccccc3)c4c(c5ccccc5)c6cc(Cl)ccc6[nH]c4=O)CC1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E06 compound treatment 1478445.0 -175000.0 -0.3 1756768.0 -174000.0 -0.28 -0.4109 -0.9998 3631402 CBKinase1_021448 CC(NS(=O)(=O)c1ccccc1)C(=O)Nc2cc(Cl)ccc2Oc3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E07 compound treatment 1714731.0 61300.0 0.1 1896754.0 -33900.0 -0.06 0.0341 0.2897 3631403 CBKinase1_021449 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2ccc3OCCOc3c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E08 compound treatment 1884745.0 231000.0 0.39 2306955.0 376000.0 0.62 0.713 0.976 3631404 CBKinase1_021450 COC(=O)c1ccc(NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E09 mock treatment 1824759.0 171000.0 0.29 2284591.0 354000.0 0.58 0.6153 0.9487 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E10 mock treatment 1784479.0 131000.0 0.22 2218976.0 288000.0 0.47 0.491 0.9406 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E11 compound treatment 1701355.0 47900.0 0.08 2360933.0 430000.0 0.71 0.556 0.7833 3631405 CBKinase1_021451 COc1ccc(OC)c(c1)S(=O)(=O)N(C)CC(=O)N2CCN(CC2)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E12 compound treatment 2030521.0 377000.0 0.64 2510396.0 580000.0 0.95 1.1232 0.9813 3631406 CBKinase1_021452 Cc1ccc(NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E13 compound treatment 1857096.0 204000.0 0.34 2678696.0 748000.0 1.23 1.1107 0.8721 3631407 CBKinase1_021453 Cc1ccc(cc1NC(=O)CCn2cnc3ccccc3c2=O)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E14 compound treatment 1623726.0 -29700.0 -0.05 2035766.0 105000.0 0.17 0.0863 0.4807 3631408 CBKinase1_021454 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2cccc(c2)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E15 compound treatment 1629270.0 -24200.0 -0.04 1854817.0 -75800.0 -0.12 -0.1168 -0.8927 3631409 CBKinase1_021455 CCOC(=O)c1c(NC(=O)Cn2cnc3ccccc3c2=O)scc1c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E16 compound treatment 1439326.0 -214000.0 -0.36 2333878.0 403000.0 0.66 0.211 0.28 3631410 CBKinase1_021456 COc1ccccc1NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E17 mock treatment 2236507.0 583000.0 0.99 2357155.0 427000.0 0.7 1.1922 0.9857 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E18 mock treatment 1663761.0 10300.0 0.02 2303195.0 373000.0 0.61 0.4441 0.7271 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E19 compound treatment 1895117.0 242000.0 0.41 2076135.0 145000.0 0.24 0.4579 0.967 3631411 CBKinase1_021457 FC(F)(F)c1cc(nc(SCC(=O)N2CCCc3ccccc23)n1)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E20 compound treatment 1956722.0 303000.0 0.51 2023562.0 92900.0 0.15 0.4707 0.879 3631412 CBKinase1_021458 COC(=O)c1sccc1NC(=O)CSc2nnnn2c3ccccc3F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E21 compound treatment 1820768.0 167000.0 0.28 1724575.0 -206000.0 -0.34 -0.0385 -0.0874 3631413 CBKinase1_021459 FC(F)(F)c1cc(nc(SCCC(=O)N2CCN(CC2)c3ccccn3)n1)c4ccco4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E22 compound treatment 1694103.0 40700.0 0.07 1557414.0 -373000.0 -0.61 -0.3838 -0.6236 3027242 CBKinase1_021460 O=C(NCCc1c[nH]c2ccccc12)c3ccccn3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E23 compound treatment 1738110.0 84700.0 0.14 1853922.0 -76700.0 -0.13 0.0125 0.0653 3631414 CBKinase1_021461 FC(F)(F)c1cc(nc(SCC(=O)Nc2sc3CCCc3c2C#N)n1)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 E24 compound treatment 1278560.0 -375000.0 -0.63 1850267.0 -80400.0 -0.13 -0.5418 -0.8361 1788894 CBKinase1_021462 Cc1nn(Cc2cccc(Oc3ccccc3)c2)c(C)c1NC(=O)c4nc5ncccn5n4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F01 mock treatment 1291349.0 -362000.0 -0.61 1453157.0 -477000.0 -0.78 -0.9867 -0.9927 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F02 mock treatment 1339945.0 -313000.0 -0.53 1760869.0 -170000.0 -0.28 -0.572 -0.9546 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F03 compound treatment 1439739.0 -214000.0 -0.36 1768545.0 -162000.0 -0.27 -0.4436 -0.9885 3631415 CBKinase1_021463 Cc1cc(NC(=O)CCSc2nc(cc(n2)C(F)(F)F)c3ccco3)n(n1)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F04 compound treatment 1630793.0 -22600.0 -0.04 1860577.0 -70100.0 -0.11 -0.1083 -0.8945 3631416 CBKinase1_021464 COc1ccc(cc1)N(C(=O)c2ccccc2)S(=O)(=O)c3cccc(c3)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F05 compound treatment 1732705.0 79300.0 0.13 1911130.0 -19500.0 -0.03 0.0723 0.5239 3631417 CBKinase1_021465 Cc1cc(C(F)F)n2nc(nc2n1)C(=O)Nc3cnn(Cc4ccc(Cl)cc4Cl)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F06 compound treatment 1699278.0 45900.0 0.08 2038489.0 108000.0 0.18 0.1799 0.9317 3631418 CBKinase1_021466 CSCC(NS(=O)(=O)c1ccc(Br)cc1)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F07 compound treatment 1404609.0 -249000.0 -0.42 1654273.0 -276000.0 -0.45 -0.6181 -0.9993 3631419 CBKinase1_021467 CCN1CCN(CC1)c2c(Cl)cccc2NC(=O)c3ccc(o3)c4ccccc4[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F08 compound treatment 1652963.0 -461.0 0.0 2127876.0 197000.0 0.32 0.228 0.7054 3631420 CBKinase1_021468 Brc1ccc(NC(=O)CSc2nnc(c3ccccn3)n2c4ccccc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F09 mock treatment 1868885.0 215000.0 0.36 2158149.0 228000.0 0.37 0.5215 0.9999 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F10 mock treatment 1677925.0 24500.0 0.04 2101237.0 171000.0 0.28 0.227 0.8032 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F11 compound treatment 1789493.0 136000.0 0.23 2407569.0 477000.0 0.78 0.7156 0.8781 3631421 CBKinase1_021469 COc1ccc(cc1)C(=O)NCc2occc2C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F12 compound treatment 1711942.0 58500.0 0.1 2321522.0 391000.0 0.64 0.523 0.8069 3631422 CBKinase1_021470 COc1ccc(cc1)n2c(SCC(=O)Nc3ccc(cc3)C(=O)N)nc4sc5CCCCc5c4c2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F13 compound treatment 1834270.0 181000.0 0.31 2637065.0 706000.0 1.16 1.0351 0.8644 3631423 CBKinase1_021471 CC(NS(=O)(=O)c1ccccc1)C(=O)Nc2ccccc2F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F14 compound treatment 1526257.0 -127000.0 -0.22 2156799.0 226000.0 0.37 0.1099 0.2563 3631424 CBKinase1_021472 COc1ccc(NC(=O)C(C)N(c2ccc(Cl)cc2)S(=O)(=O)C)c(OC)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F15 compound treatment 1644158.0 -9270.0 -0.02 2185344.0 255000.0 0.42 0.2841 0.6801 3631425 CBKinase1_021473 Cc1ccccc1NC(=O)c2ccc(OCC(=O)Nc3ccccc3C(F)(F)F)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F16 compound treatment 1486396.0 -167000.0 -0.28 2101282.0 171000.0 0.28 -0.0022 -0.0055 3631426 CBKinase1_021474 Cc1cc(ccc1Br)N(CC(=O)Nc2cc(Cl)ccc2Cl)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F17 mock treatment 1861467.0 208000.0 0.35 2265387.0 335000.0 0.55 0.6369 0.977 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F18 mock treatment 1729231.0 75800.0 0.13 2231074.0 300000.0 0.49 0.4389 0.8626 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F19 compound treatment 1596687.0 -56700.0 -0.1 2041198.0 111000.0 0.18 0.0602 0.2936 3631427 CBKinase1_021475 COC(=O)CSc1nnc(c2sc3ccccc3c2Cl)n1c4ccc(OC)cc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F20 compound treatment 1565783.0 -87600.0 -0.15 1873588.0 -57100.0 -0.09 -0.171 -0.9752 1725736 CBKinase1_021476 Clc1ccc(cc1)c2nnc(SCC(=O)N3c4ccccc4Sc5ccccc35)o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F21 compound treatment 1589315.0 -64100.0 -0.11 2026999.0 96400.0 0.16 0.0349 0.1823 3631428 CBKinase1_021477 Fc1ccc(cc1)C(=O)CSc2nnc(c3cccs3)n2c4cccc(c4)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F22 compound treatment 1721764.0 68300.0 0.12 2003438.0 72800.0 0.12 0.1662 0.9999 3631429 CBKinase1_021478 COc1cccc(NC(=O)C(C)N(c2cc(C)cc(C)c2)S(=O)(=O)C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F23 compound treatment 1694423.0 41000.0 0.07 2106682.0 176000.0 0.29 0.2531 0.8529 3631430 CBKinase1_021479 Cn1c(SCC(=O)Nc2ccc(Oc3ccccc3)cc2)nnc1c4cccs4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 F24 compound treatment 1506413.0 -147000.0 -0.25 1785183.0 -145000.0 -0.24 -0.3445 -0.9998 3631431 CBKinase1_021480 CS(=O)(=O)N(CC(=O)Nc1cccc(c1)C(F)(F)F)c2cc(Cl)c(Cl)cc2Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G01 compound treatment 1232301.0 -421000.0 -0.71 1577259.0 -353000.0 -0.58 -0.9136 -0.9947 3631432 CBKinase1_021481 COc1ccccc1c2nnc(SCC(=O)c3ccc(Cl)cc3)n2c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G02 compound treatment 1433902.0 -220000.0 -0.37 1881440.0 -49200.0 -0.08 -0.3198 -0.841 3631433 CBKinase1_021482 CN1CCN(CC1)C(=O)COc2ccc(cc2Cl)S(=O)(=O)NC3CCCCC3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G03 mock treatment 1589738.0 -63700.0 -0.11 1925063.0 -5580.0 -0.01 -0.0827 -0.7644 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G04 mock treatment 1582954.0 -70500.0 -0.12 1788848.0 -142000.0 -0.23 -0.2487 -0.952 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G05 compound treatment 1719593.0 66200.0 0.11 2019475.0 88800.0 0.15 0.1821 0.9916 3631434 CBKinase1_021483 CS(=O)(=O)Nc1ccc(cc1)C(=O)CC2(O)C(=O)Nc3ccc(Br)cc32 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G06 compound treatment 1588848.0 -64600.0 -0.11 1915956.0 -14700.0 -0.02 -0.0943 -0.8426 3631435 CBKinase1_021484 CC(NS(=O)(=O)c1ccc(Br)cc1)C(=O)Nc2cccc(F)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G07 compound treatment 1637770.0 -15700.0 -0.03 2005715.0 75100.0 0.12 0.0683 0.5424 3631436 CBKinase1_021485 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2cccc(SC)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G08 compound treatment 1783925.0 131000.0 0.22 2152140.0 221000.0 0.36 0.4129 0.9716 3631437 CBKinase1_021486 CC(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccc(C)c(Cl)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G09 compound treatment 1763034.0 110000.0 0.19 2289423.0 359000.0 0.59 0.547 0.8871 3631438 CBKinase1_021487 COc1ccc(OC)c(c1)S(=O)(=O)N(C)CC(=O)Nc2ccc(F)c(Cl)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G10 compound treatment 1621223.0 -32200.0 -0.05 1989195.0 58500.0 0.1 0.0293 0.2656 3631439 CBKinase1_021488 COc1ccc(OC)c(NC(=O)Cn2cc(C(=O)C3CC3)c4ccccc24)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G11 compound treatment 1817726.0 164000.0 0.28 2440084.0 509000.0 0.83 0.787 0.8943 3631440 CBKinase1_021489 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2ccccc2F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G12 compound treatment 1519364.0 -134000.0 -0.23 2126022.0 195000.0 0.32 0.066 0.1681 3631441 CBKinase1_021490 O=C(c1ccco1)c2cn(CCCOc3ccccc3)c4ccccc24 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G13 compound treatment 1709142.0 55700.0 0.09 2224626.0 294000.0 0.48 0.4074 0.8298 3631442 CBKinase1_021491 CN1C(=O)c2ccc(NC(=O)CCn3cnc4ccccc4c3=O)cc2C1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G14 compound treatment 1901440.0 248000.0 0.42 2041293.0 111000.0 0.18 0.4251 0.9295 3631443 CBKinase1_021492 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Cl)c2cc(Cl)c(Cl)cc2Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G15 compound treatment 1658847.0 5420.0 0.01 2291568.0 361000.0 0.59 0.4248 0.718 3631444 CBKinase1_021493 Cc1cccc(C)c1NC(=O)CCn2cnc3ccccc3c2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G16 compound treatment 1733273.0 79800.0 0.14 2408058.0 477000.0 0.78 0.6488 0.8172 3631445 CBKinase1_021494 Cc1cccc(C)c1OCC(=O)NCc2ccccn2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G17 compound treatment 1736052.0 82600.0 0.14 2060781.0 130000.0 0.21 0.2497 0.9791 3027153 CBKinase1_021495 CCc1cc(C(=O)N2CCOCC2)c(NC3=NS(=O)(=O)c4ccccc34)s1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G18 compound treatment 1653361.0 -62.7 0.0 2281983.0 351000.0 0.58 0.4071 0.707 3631446 CBKinase1_021496 CC(=O)c1cccc(NC(=O)C2CCCN(C2)S(=O)(=O)c3ccc(F)cc3)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G19 mock treatment 1579966.0 -73500.0 -0.12 2098929.0 168000.0 0.28 0.1071 0.354 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G20 mock treatment 1514815.0 -139000.0 -0.23 1818031.0 -113000.0 -0.18 -0.2964 -0.9929 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G21 compound treatment 1597306.0 -56100.0 -0.09 1903415.0 -27200.0 -0.04 -0.0987 -0.9407 3631447 CBKinase1_021497 COc1ccccc1NC(=O)NCCc2ccncc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G22 compound treatment 1631952.0 -21500.0 -0.04 1950559.0 19900.0 0.03 -0.0026 -0.0537 3631448 CBKinase1_021498 Cn1c(=O)n(C)c2nc(SCc3nnn[nH]3)n(Cc4ccccc4)c2c1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G23 compound treatment 1648560.0 -4860.0 -0.01 1887723.0 -42900.0 -0.07 -0.0556 -0.7845 3631449 CBKinase1_021499 CCc1c(C)sc(NC(=O)CSc2nc(cc(n2)C(F)(F)F)c3ccccc3)c1C#N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 G24 compound treatment 1115682.0 -538000.0 -0.91 1701777.0 -229000.0 -0.38 -0.9089 -0.9232 3631450 CBKinase1_021500 CN(Cc1c(C)nn(C)c1C)C(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc(Cl)cc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H01 compound treatment 1257888.0 -396000.0 -0.67 1647294.0 -283000.0 -0.46 -0.8018 -0.984 3631451 CBKinase1_021501 FC(F)(F)c1cc(=O)oc2cc(NC(=O)c3nc4ncccn4n3)ccc12 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H02 compound treatment 1484960.0 -168000.0 -0.29 1782949.0 -148000.0 -0.24 -0.3728 -0.9967 3631452 CBKinase1_021502 Cc1ccc(cc1)c2csc3ncnc(SCC(=O)c4ccc(F)cc4)c23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H03 mock treatment 1475764.0 -178000.0 -0.3 1847950.0 -82700.0 -0.14 -0.3085 -0.9352 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H04 mock treatment 1511514.0 -142000.0 -0.24 1937199.0 6550.0 0.01 -0.1623 -0.6748 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H05 compound treatment 1606746.0 -46700.0 -0.08 2575071.0 644000.0 1.06 0.6909 0.6524 3631453 CBKinase1_021503 FC(F)c1cc(nc2c(cnn12)C(=O)NCc3ccco3)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H06 compound treatment 1518009.0 -135000.0 -0.23 1889485.0 -41200.0 -0.07 -0.2098 -0.878 3631454 CBKinase1_021504 COc1ccc(cc1)S(=O)(=O)NC2(CCCCC2)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H07 compound treatment 1545564.0 -108000.0 -0.18 1917984.0 -12700.0 -0.02 -0.1438 -0.7824 3631455 CBKinase1_021505 CS(=O)(=O)N1CCN(CC1)c2ccccc2NC(=O)c3ccc(N4CCCCC4)c(c3)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H08 compound treatment 1612419.0 -41000.0 -0.07 2130431.0 200000.0 0.33 0.1824 0.5451 3631456 CBKinase1_021506 [O-][N+](=O)c1ccc(CSc2nnc(c3ccccn3)n2c4ccccc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H09 compound treatment 1646028.0 -7400.0 -0.01 2167076.0 236000.0 0.39 0.2651 0.6839 3631457 CBKinase1_021507 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2cccc(Cl)c2N3CCOCC3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H10 compound treatment 889790.0 -764000.0 -1.29 1058524.0 -872000.0 -1.43 -1.9247 -0.9987 3631458 CBKinase1_021508 COc1ccc(OC)c(c1)C(=O)CSc2nnc(c3ccccn3)n2c4ccc(C)cc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H11 compound treatment 1780350.0 127000.0 0.21 2285125.0 354000.0 0.58 0.5627 0.9085 3631459 CBKinase1_021509 COc1ccc(cc1)C(=O)NCc2oc(cc2C(=O)O)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H12 compound treatment 1768753.0 115000.0 0.2 2202981.0 272000.0 0.45 0.4536 0.9312 3631460 CBKinase1_021510 CCc1cccc(C)c1NC(=O)CSc2nc3ccccc3c(=O)n2c4ccc(C)cc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H13 compound treatment 1738417.0 85000.0 0.14 2314273.0 384000.0 0.63 0.5463 0.847 3631461 CBKinase1_021511 CC(NS(=O)(=O)c1ccccc1)C(=O)Nc2ccc(F)c(Cl)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H14 compound treatment 1530788.0 -123000.0 -0.21 2136098.0 205000.0 0.34 0.0913 0.2308 3631462 CBKinase1_021512 COc1ccc(C)cc1S(=O)(=O)NCc2ccncc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H15 compound treatment 1624821.0 -28600.0 -0.05 2196075.0 265000.0 0.44 0.2734 0.6246 3631463 CBKinase1_021513 Fc1ccccc1NC(=O)COc2ccc(cc2)C(=O)Nc3cccc(c3)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H16 compound treatment 1592603.0 -60800.0 -0.1 2255405.0 325000.0 0.53 0.3036 0.56 3631464 CBKinase1_021514 CNC(=O)CN(c1cc(Cl)c(Cl)cc1Cl)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H17 compound treatment 1635881.0 -17500.0 -0.03 2131246.0 201000.0 0.33 0.2115 0.6406 3631465 CBKinase1_021515 COC(=O)c1ccccc1NC(=O)CSc2ncnc3sc4CC(C)CCc4c23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H18 compound treatment 1438854.0 -215000.0 -0.36 1825882.0 -105000.0 -0.17 -0.3782 -0.9415 3631466 CBKinase1_021516 O=C(Cn1cc(C(=O)c2ccco2)c3ccccc13)N4CCCc5ccccc45 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H19 mock treatment 1502127.0 -151000.0 -0.26 1856032.0 -74600.0 -0.12 -0.2676 -0.9428 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H20 mock treatment 1476376.0 -177000.0 -0.3 1978910.0 48300.0 0.08 -0.156 -0.5032 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H21 compound treatment 1450887.0 -203000.0 -0.34 1820134.0 -111000.0 -0.18 -0.3705 -0.9555 3631467 CBKinase1_021517 CCOC(=O)c1c(C)c(C)sc1NC(=O)c2ccc(C)c(c2)S(=O)(=O)N3CCCC3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H22 compound treatment 1537014.0 -116000.0 -0.2 1894821.0 -35800.0 -0.06 -0.1808 -0.8796 3631468 CBKinase1_021518 COc1cc(OC)cc(c1)c2nnc(SCc3cccc(c3)C(=O)O)o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H23 compound treatment 1506188.0 -147000.0 -0.25 1703118.0 -228000.0 -0.37 -0.4399 -0.9808 3631469 CBKinase1_021519 COc1ccc(OC)c(c1)C(=O)CSc2nnc(c3cccs3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 H24 compound treatment 1008328.0 -645000.0 -1.09 1798870.0 -132000.0 -0.22 -0.9248 -0.8309 3631470 CBKinase1_021520 OC(=O)c1cccc(CSc2nnc(o2)c3ccc(Cl)cc3)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I01 compound treatment 1285454.0 -368000.0 -0.62 1643992.0 -287000.0 -0.47 -0.7726 -0.9903 3631471 CBKinase1_021521 COc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(F)c3)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I02 compound treatment 1488345.0 -165000.0 -0.28 2813047.0 882000.0 1.45 0.825 0.5601 3631472 CBKinase1_021522 C=CCOc1ccc2ccccc2c1CNc3nn[nH]n3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I03 compound treatment 1541935.0 -111000.0 -0.19 1749073.0 -182000.0 -0.3 -0.3439 -0.9758 3631473 CBKinase1_021523 COc1cc(OC)cc(OCC(O)Cn2cnc(c2)c3ccccc3)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I04 compound treatment 1270232.0 -383000.0 -0.65 1437199.0 -493000.0 -0.81 -1.0305 -0.994 3631474 CBKinase1_021524 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3ccc(Oc4ccccc4)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I05 mock treatment 1590649.0 -62800.0 -0.11 1961158.0 30500.0 0.05 -0.0398 -0.3387 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I06 mock treatment 1597024.0 -56400.0 -0.1 2077891.0 147000.0 0.24 0.1031 0.3974 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I07 compound treatment 1719813.0 66400.0 0.11 1734481.0 -196000.0 -0.32 -0.1479 -0.4342 3631475 CBKinase1_021525 CCN(CC(=O)Nc1c(C)cc(C)cc1C)S(=O)(=O)c2ccc3ccccc3c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I08 compound treatment 1644308.0 -9120.0 -0.02 2134521.0 204000.0 0.33 0.2254 0.6737 1986138 CBKinase1_021526 OC(=O)Cn1cc(C(=O)C2CCCCC2)c3ccccc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I09 compound treatment 1674677.0 21300.0 0.04 2049241.0 119000.0 0.19 0.1629 0.824 3631476 CBKinase1_021527 COc1ccc(OC)c(c1)S(=O)(=O)N(C)CC(=O)Nc2ccc3OCCOc3c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I10 compound treatment 1635478.0 -17900.0 -0.03 2256587.0 326000.0 0.53 0.3562 0.6658 3631477 CBKinase1_021528 CC(=O)c1cccc(c1)N(CC(=O)Nc2cc(C)cc(C)c2)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I11 compound treatment 1642644.0 -10800.0 -0.02 2145339.0 215000.0 0.35 0.2359 0.6695 3631478 CBKinase1_021529 CC1CCCC(C)N1S(=O)(=O)c2ccc(NC(=O)CCn3cnc4ccccc4c3=O)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I12 compound treatment 1762001.0 109000.0 0.18 2274154.0 344000.0 0.56 0.528 0.8916 3631479 CBKinase1_021530 CC(N(c1cc(C)cc(C)c1)S(=O)(=O)C)C(=O)Nc2cccc3ccccc23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I13 compound treatment 1650312.0 -3110.0 -0.01 2250178.0 320000.0 0.52 0.3666 0.7 3631480 CBKinase1_021531 Cc1ccc(NC(=O)CCn2cnc3ccccc3c2=O)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I14 compound treatment 1701986.0 48600.0 0.08 2133687.0 203000.0 0.33 0.2934 0.8561 3631481 CBKinase1_021532 CC(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccc(C)cc2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I15 compound treatment 1702942.0 49500.0 0.08 1992683.0 62000.0 0.1 0.1312 0.9954 3631482 CBKinase1_021533 O=C(CCn1cnc2ccccc2c1=O)Nc3ccc-4c(Cc5ccccc54)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I16 compound treatment 1641828.0 -11600.0 -0.02 1948114.0 17500.0 0.03 0.0064 0.1834 3631483 CBKinase1_021534 Cc1ccc(NC(=O)CSc2nc(c3CCCCc3n2)C(F)(F)F)cc1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I17 compound treatment 1919688.0 266000.0 0.45 2180881.0 250000.0 0.41 0.6087 0.9989 3631484 CBKinase1_021535 COc1ccc(OC)c(NC(=O)Cn2c(=O)oc3ccccc23)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I18 compound treatment 1552424.0 -101000.0 -0.17 2002242.0 71600.0 0.12 -0.0379 -0.1829 3631485 CBKinase1_021536 COc1ccc(NC(=O)Cn2cc(C(=O)C(C)C)c3ccccc23)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I19 compound treatment 1592594.0 -60800.0 -0.1 2065146.0 135000.0 0.22 0.0831 0.3414 3631486 CBKinase1_021537 FC(F)(F)c1cc(nc(SCC(=O)Nc2sc3CCCCCc3c2C#N)n1)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I20 compound treatment 1672521.0 19100.0 0.03 2001267.0 70600.0 0.12 0.1047 0.8713 3631487 CBKinase1_021538 COc1cc(NC(=O)Cn2nnc(n2)c3ccccc3Cl)cc(OC)c1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I21 mock treatment 1744101.0 90700.0 0.15 1878283.0 -52400.0 -0.09 0.0479 0.2721 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I22 mock treatment 1615645.0 -37800.0 -0.06 1812492.0 -118000.0 -0.19 -0.1821 -0.8932 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I23 compound treatment 1260510.0 -393000.0 -0.67 1677349.0 -253000.0 -0.42 -0.7638 -0.9743 3631488 CBKinase1_021539 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3cccc(SC)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 I24 compound treatment 1524132.0 -129000.0 -0.22 1825081.0 -106000.0 -0.17 -0.2771 -0.9932 3631489 CBKinase1_021540 Cc1c(CNC(=O)c2cnn3C(CC(Nc23)c4ccc(Br)cc4)C(F)(F)F)cnn1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J01 compound treatment 1132351.0 -521000.0 -0.88 1349143.0 -582000.0 -0.95 -1.2976 -0.9993 1788860 CBKinase1_021541 Cc1ccc(O)c(NC(=O)c2nc3ncccn3n2)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J02 compound treatment 1321922.0 -332000.0 -0.56 1594581.0 -336000.0 -0.55 -0.7862 -1.0 3631490 CBKinase1_021542 Fc1ccccc1c2nnc(SCC(=O)Nc3ccc(Br)cc3)n2c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J03 compound treatment 1293816.0 -360000.0 -0.61 1541811.0 -389000.0 -0.64 -0.881 -0.9997 3631491 CBKinase1_021543 NC(=O)c1c(NC(=O)CCSc2nc(cc(n2)C(F)(F)F)c3ccco3)sc4CCCc14 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J04 compound treatment 1514473.0 -139000.0 -0.24 1755476.0 -175000.0 -0.29 -0.3693 -0.9951 3631492 CBKinase1_021544 COc1ccc(cc1)N(C(=O)c2cccnc2)S(=O)(=O)c3cccc(c3)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J05 mock treatment 1591846.0 -61600.0 -0.1 1883512.0 -47100.0 -0.08 -0.1283 -0.9891 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J06 mock treatment 1524756.0 -129000.0 -0.22 1737118.0 -194000.0 -0.32 -0.3783 -0.9832 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J07 compound treatment 1688588.0 35200.0 0.06 1862695.0 -68000.0 -0.11 -0.0367 -0.2903 3631493 CBKinase1_021545 Cc1cc(OCC(=O)Nc2cccc3ncccc23)ccc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J08 compound treatment 1472376.0 -181000.0 -0.31 1959453.0 28800.0 0.05 -0.1833 -0.5912 3631494 CBKinase1_021546 FC(F)(F)c1ccc(Cl)c(NC(=O)CSc2nnc(c3ccccn3)n2c4ccccc4)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J09 compound treatment 1365755.0 -288000.0 -0.49 1801187.0 -129000.0 -0.21 -0.4943 -0.9307 1236244 CBKinase1_021547 Brc1ccc(OCC(=O)Nc2cccc3ncccc23)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J10 compound treatment 1422011.0 -231000.0 -0.39 1798487.0 -132000.0 -0.22 -0.4301 -0.961 3631495 CBKinase1_021548 Cn1c(SCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)nnc1c3cnccn3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J11 compound treatment 1909323.0 256000.0 0.43 2225663.0 295000.0 0.48 0.6482 0.9985 3631496 CBKinase1_021549 Cc1cc(Br)c(NC(=O)CSc2nccc(=O)[nH]2)cc1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J12 compound treatment 1564792.0 -88600.0 -0.15 2160919.0 230000.0 0.38 0.1608 0.3959 3631497 CBKinase1_021550 Cc1ccc(cc1)n2c(SCC(=O)Nc3c(F)cc(F)cc3Br)nc4ccccc4c2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J13 compound treatment 1385314.0 -268000.0 -0.45 1777023.0 -154000.0 -0.25 -0.4989 -0.9614 3631498 CBKinase1_021551 CC(NS(=O)(=O)c1ccccc1)C(=O)Nc2ccccc2C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J14 compound treatment 1589043.0 -64400.0 -0.11 1871662.0 -59000.0 -0.1 -0.1454 -0.9982 3631499 CBKinase1_021552 COC(=O)c1ccc(NC(=O)C(C)N(c2ccc(Cl)cc2)S(=O)(=O)C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J15 compound treatment 1485118.0 -168000.0 -0.28 2046621.0 116000.0 0.19 -0.067 -0.1958 3631500 CBKinase1_021553 COC(=O)c1c(NC(=S)NC(=O)CN2C(=O)c3ccccc3C2=O)sc4CCCCc14 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J16 compound treatment 1591653.0 -61800.0 -0.1 1991932.0 61300.0 0.1 -0.0029 -0.0201 3631501 CBKinase1_021554 CN(C)S(=O)(=O)N(CC(=O)O)c1ccccc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J17 compound treatment 1462322.0 -191000.0 -0.32 1796605.0 -134000.0 -0.22 -0.3841 -0.9822 3631502 CBKinase1_021555 CC1CCc2c(C1)sc3ncnc(SCCOc4ccccc4)c23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J18 compound treatment 1517569.0 -136000.0 -0.23 1699679.0 -231000.0 -0.38 -0.4303 -0.9715 3631503 CBKinase1_021556 COc1ccc(cc1N(CC(=O)Nc2ccccc2Br)S(=O)(=O)C)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J19 compound treatment 1562086.0 -91300.0 -0.15 1799067.0 -132000.0 -0.22 -0.2618 -0.9867 3631504 CBKinase1_021557 CCOC(=O)c1c(C)c(C)sc1NC(=O)c2ccc(C)c(c2)S(=O)(=O)N3CCOCC3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J20 compound treatment 1668112.0 14700.0 0.02 1943256.0 12600.0 0.02 0.0322 0.9958 3631505 CBKinase1_021558 CNC(=O)C(C)N(c1cc(C)cc(C)c1)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J21 mock treatment 1517095.0 -136000.0 -0.23 1814000.0 -117000.0 -0.19 -0.2984 -0.9956 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J22 mock treatment 1475939.0 -177000.0 -0.3 1959555.0 28900.0 0.05 -0.1789 -0.5883 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J23 compound treatment 1683276.0 29900.0 0.05 1822131.0 -109000.0 -0.18 -0.09 -0.4869 3631506 CBKinase1_021559 Cn1c(SCC(=O)c2ccc(cc2)[N+](=O)[O-])nnc1c3cccs3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 J24 compound treatment 1295751.0 -358000.0 -0.61 1542852.0 -388000.0 -0.64 -0.8775 -0.9997 3631507 CBKinase1_021560 CC(N(c1cc(C)cc(C)c1)S(=O)(=O)C)C(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K01 compound treatment 1147863.0 -506000.0 -0.86 1277971.0 -653000.0 -1.07 -1.3615 -0.9939 3631508 CBKinase1_021561 Cn1c(SCC(=O)N)nnc1c2ccc(cc2)C(C)(C)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K02 compound treatment 1153116.0 -500000.0 -0.85 1313074.0 -618000.0 -1.01 -1.3145 -0.9961 3631509 CBKinase1_021562 COc1ccc(CCNCc2cc(Cl)cc(Cl)c2OC)cc1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K03 compound treatment 1551145.0 -102000.0 -0.17 1572990.0 -358000.0 -0.59 -0.5369 -0.8784 3631510 CBKinase1_021563 CC(=O)c1ccccc1OCC(O)Cn2cnc3ccccc23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K04 compound treatment 1257249.0 -396000.0 -0.67 1346090.0 -585000.0 -0.96 -1.1516 -0.9848 3631511 CBKinase1_021564 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3ccc4OCCOc4c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K05 compound treatment 1526777.0 -127000.0 -0.21 1642205.0 -288000.0 -0.47 -0.4859 -0.936 3631512 CBKinase1_021565 OC1(CC(=O)c2ccc(NS(=O)(=O)c3ccccc3)cc2)C(=O)Nc4ccc(Br)cc41 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K06 compound treatment 1603137.0 -50300.0 -0.09 2736692.0 806000.0 1.32 0.8739 0.6602 3631513 CBKinase1_021566 Fc1ccc(NC(=O)CSc2nnc([nH]2)c3ccncc3)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K07 mock treatment 1730515.0 77100.0 0.13 1873570.0 -57100.0 -0.09 0.0261 0.1627 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K08 mock treatment 1607215.0 -46200.0 -0.08 2005385.0 74700.0 0.12 0.0313 0.2154 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K09 compound treatment 1731398.0 78000.0 0.13 2143083.0 212000.0 0.35 0.3395 0.9118 3631514 CBKinase1_021567 COc1ccc(OC)c(c1)S(=O)(=O)N(C)CC(=O)N2CCCC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K10 compound treatment 1648237.0 -5190.0 -0.01 1972255.0 41600.0 0.07 0.042 0.611 3631515 CBKinase1_021568 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccco3)c4ccccc24)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K11 compound treatment 1661941.0 8520.0 0.01 2228113.0 297000.0 0.49 0.3549 0.7277 3631516 CBKinase1_021569 Oc1ccc(cc1)N(Cc2ccco2)C(=O)c3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K12 compound treatment 1735632.0 82200.0 0.14 1868223.0 -62400.0 -0.1 0.0261 0.1509 3631517 CBKinase1_021570 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2ccc(Oc3ccccc3)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K13 compound treatment 1575758.0 -77700.0 -0.13 2142677.0 212000.0 0.35 0.1528 0.4112 3631518 CBKinase1_021571 O=C(CCn1cnc2ccccc2c1=O)Nc3ccc(cc3)S(=O)(=O)N4CCOCC4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K14 compound treatment 1875936.0 223000.0 0.38 2540744.0 610000.0 1.0 0.9734 0.911 3631519 CBKinase1_021572 CC(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccc(I)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K15 mock treatment 1598724.0 -54700.0 -0.09 1839807.0 -90800.0 -0.15 -0.1707 -0.9739 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K16 mock treatment 1625499.0 -27900.0 -0.05 1908418.0 -22200.0 -0.04 -0.0592 -0.9917 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K17 compound treatment 1729169.0 75700.0 0.13 1818449.0 -112000.0 -0.18 -0.0394 -0.1756 3631520 CBKinase1_021573 OC(=O)c1cccc(NC(=O)Cn2c(=O)oc3ccccc23)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K18 compound treatment 1488136.0 -165000.0 -0.28 1690836.0 -240000.0 -0.39 -0.4757 -0.9861 3631521 CBKinase1_021574 Fc1ccc(NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3Cl)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K19 compound treatment 1322180.0 -331000.0 -0.56 1563895.0 -367000.0 -0.6 -0.8215 -0.9994 3631522 CBKinase1_021575 FC(F)(F)c1cc(nc(SCC(=O)Nc2ccc3CCCc3c2)n1)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K20 compound treatment 1689282.0 35900.0 0.06 1646796.0 -284000.0 -0.47 -0.286 -0.6097 3631523 CBKinase1_021576 CCOC(=O)c1c(NC(=O)COc2ccccc2F)sc3CCCCc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K21 compound treatment 1582507.0 -70900.0 -0.12 1711909.0 -219000.0 -0.36 -0.3384 -0.895 3631524 CBKinase1_021577 Cc1onc(c1C(=O)NCc2ccc(cc2)N3CCCC3=O)c4ccccc4Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K22 compound treatment 1707061.0 53600.0 0.09 1911244.0 -19400.0 -0.03 0.0417 0.4336 3631525 CBKinase1_021578 Cn1c(Cn2nnc(n2)c3ccccc3)nnc1SCC(=O)N 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K23 mock treatment 1550400.0 -103000.0 -0.17 1859857.0 -70800.0 -0.12 -0.2053 -0.9804 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 K24 mock treatment 1463934.0 -189000.0 -0.32 1537583.0 -393000.0 -0.64 -0.6823 -0.9482 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L01 compound treatment 1202762.0 -451000.0 -0.76 1301268.0 -629000.0 -1.03 -1.2688 -0.989 1788861 CBKinase1_021579 COC(=O)c1ccccc1NC(=O)c2nc3ncccn3n2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L02 compound treatment 1364619.0 -289000.0 -0.49 1638892.0 -292000.0 -0.48 -0.6838 -0.9999 3631526 CBKinase1_021580 NC(=O)CSc1nnc(c2ccccc2F)n1c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L03 compound treatment 1457788.0 -196000.0 -0.33 1679183.0 -251000.0 -0.41 -0.5256 -0.9941 3631527 CBKinase1_021581 NC(=O)c1c(NC(=O)CCSc2nc(cc(n2)C(F)(F)F)c3ccco3)sc4CCCCc14 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L04 compound treatment 1520351.0 -133000.0 -0.23 1561001.0 -370000.0 -0.61 -0.5876 -0.9092 3631528 CBKinase1_021582 COc1ccc(cc1)N(C(=O)c2ccncc2)S(=O)(=O)c3cccc(c3)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L05 compound treatment 1823228.0 170000.0 0.29 1825267.0 -105000.0 -0.17 0.0811 0.2419 3631529 CBKinase1_021583 COc1ccc(cc1NC(=O)COc2ccc(cc2)C(C)(C)C)c3cc4ccccc4oc3=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L06 compound treatment 1590233.0 -63200.0 -0.11 1674452.0 -256000.0 -0.42 -0.3725 -0.8598 3631530 CBKinase1_021584 COC(=O)Cc1c(C)c2c(OCC(=O)N)cc(C)cc2oc1=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L07 mock treatment 1799199.0 146000.0 0.25 1839331.0 -91300.0 -0.15 0.0687 0.2379 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L08 mock treatment 1797433.0 144000.0 0.24 1988434.0 57800.0 0.09 0.2393 0.9152 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L09 compound treatment 3498313.0 1840000.0 3.12 4044772.0 2110000.0 3.46 4.6582 0.9987 3631531 CBKinase1_021585 COc1ccc(cc1NC(=O)COc2ccc(Br)cc2)c3cc4ccccc4oc3=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L10 compound treatment 1637694.0 -15700.0 -0.03 1885980.0 -44700.0 -0.07 -0.0706 -0.9062 3631532 CBKinase1_021586 COC(=O)c1ccc(NC(=O)CSc2nnc(c3cnccn3)n2C)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L11 compound treatment 1813736.0 160000.0 0.27 1848623.0 -82000.0 -0.13 0.0968 0.3197 3631533 CBKinase1_021587 CN1C2=C(C(C3=C1CC(C)(C)CC3=O)c4ccccc4OCC(=O)Nc5ccc(F)cc5)C(=O)CC(C)(C)C2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L12 compound treatment 1803602.0 150000.0 0.25 1852833.0 -77800.0 -0.13 0.0896 0.315 3631534 CBKinase1_021588 CCOc1ccc(cc1)n2c(SCC(=O)Nc3ccc(Cl)cc3)nc4ccccc4c2=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L13 compound treatment 1753791.0 100000.0 0.17 1810867.0 -120000.0 -0.2 -0.0187 -0.0719 3631535 CBKinase1_021589 CC(NS(=O)(=O)c1ccccc1)C(=O)Nc2ccc(Cl)c(c2)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L14 compound treatment 1829538.0 176000.0 0.3 1831713.0 -98900.0 -0.16 0.0961 0.2833 3631536 CBKinase1_021590 CC(C)NS(=O)(=O)c1ccc(OCC(=O)O)c(Cl)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L15 mock treatment 1638794.0 -14600.0 -0.02 2077077.0 146000.0 0.24 0.1522 0.6308 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L16 mock treatment 1635059.0 -18400.0 -0.03 1852104.0 -78500.0 -0.13 -0.113 -0.8533 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L17 compound treatment 1285873.0 -368000.0 -0.62 1505063.0 -426000.0 -0.7 -0.9331 -0.9984 3631537 CBKinase1_021591 COc1ccc(NC(=O)CSc2ncnc3scc(c4ccccc4)c23)c(c1)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L18 compound treatment 1555942.0 -97500.0 -0.17 1876933.0 -53700.0 -0.09 -0.1789 -0.9567 3631538 CBKinase1_021592 FC(F)(F)c1nc(SCC(=O)Nc2sc3CCCCc3c2C#N)nc4CCCCc14 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L19 compound treatment 1533831.0 -120000.0 -0.2 1756575.0 -174000.0 -0.29 -0.3449 -0.9859 3631539 CBKinase1_021593 NC(=O)CSc1nnc(c2cccnc2)n1c3cccc(c3)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L20 compound treatment 1518309.0 -135000.0 -0.23 1751177.0 -179000.0 -0.29 -0.3697 -0.9923 3631540 CBKinase1_021594 COc1ccccc1NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L21 compound treatment 1488043.0 -165000.0 -0.28 1640339.0 -290000.0 -0.48 -0.5344 -0.968 2069046 CBKinase1_021595 Cn1c(SCc2nc3ccccc3s2)nnc1c4cccs4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L22 compound treatment 1488235.0 -165000.0 -0.28 1630221.0 -300000.0 -0.49 -0.5459 -0.9641 3631541 CBKinase1_021596 COc1ccc(OC)c(NC(=O)C(C)N2c3cccc4cccc(c34)S2(=O)=O)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L23 mock treatment 1505441.0 -148000.0 -0.25 1749813.0 -181000.0 -0.3 -0.3867 -0.9965 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 L24 mock treatment 1565521.0 -87900.0 -0.15 1629376.0 -301000.0 -0.49 -0.4543 -0.8811 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M01 compound treatment 1188180.0 -465000.0 -0.79 1373874.0 -557000.0 -0.91 -1.2021 -0.9973 3631542 CBKinase1_021597 COc1ccc(C)cc1NC(=O)CSc2nnc(c3ccc(cc3)C(C)(C)C)n2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M02 compound treatment 1150740.0 -503000.0 -0.85 1472264.0 -458000.0 -0.75 -1.1329 -0.9981 3631543 CBKinase1_021598 CC(NS(=O)(=O)c1ccc(Br)cc1)C(=O)Nc2cccc(c2)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M03 compound treatment 1255507.0 -398000.0 -0.67 1594273.0 -336000.0 -0.55 -0.8661 -0.9951 3631544 CBKinase1_021599 CC(=O)c1ccccc1OCC(O)Cn2ccnc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M04 compound treatment 1230451.0 -423000.0 -0.72 1446296.0 -484000.0 -0.79 -1.0676 -0.9987 3631545 CBKinase1_021600 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3ccc(OC)c(Cl)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M05 compound treatment 1517566.0 -136000.0 -0.23 1688514.0 -242000.0 -0.4 -0.4432 -0.9663 3631546 CBKinase1_021601 CS(=O)(=O)N1N=C(CC1c2ccco2)c3cccc(NS(=O)(=O)c4ccccc4)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M06 compound treatment 1292099.0 -361000.0 -0.61 1593708.0 -337000.0 -0.55 -0.8229 -0.9987 3631547 CBKinase1_021602 Cc1nc(SCC(=O)c2cccc(c2)[N+](=O)[O-])nc3CCCCc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M07 compound treatment 1620923.0 -32500.0 -0.06 1825470.0 -105000.0 -0.17 -0.1608 -0.8886 3631548 CBKinase1_021603 CCN(CC(=O)Nc1cc(ccc1C)[N+](=O)[O-])S(=O)(=O)c2ccc3ccccc3c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M08 compound treatment 1396487.0 -257000.0 -0.43 1595721.0 -335000.0 -0.55 -0.6957 -0.9934 3631549 CBKinase1_021604 CS(=O)(=O)N(CC(=O)Nc1ccc(Oc2ccccc2)cc1)c3cc(Cl)c(Cl)cc3Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M09 mock treatment 1672062.0 18600.0 0.03 1867213.0 -63400.0 -0.1 -0.0512 -0.4713 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M10 mock treatment 1635205.0 -18200.0 -0.03 1867002.0 -63600.0 -0.1 -0.0956 -0.8786 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M11 compound treatment 1669716.0 16300.0 0.03 1788229.0 -142000.0 -0.23 -0.1455 -0.6192 3631550 CBKinase1_021605 [O-][N+](=O)c1cccc(NC(=O)Cn2c(=O)oc3ccccc23)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M12 compound treatment 1757187.0 104000.0 0.18 1867412.0 -63200.0 -0.1 0.0509 0.2497 3631551 CBKinase1_021606 Cc1cc(ccc1Br)N(CC(=O)O)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M13 mock treatment 1682358.0 28900.0 0.05 2019857.0 89200.0 0.15 0.138 0.8951 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M14 mock treatment 1537512.0 -116000.0 -0.2 1947341.0 16700.0 0.03 -0.1194 -0.6027 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M15 compound treatment 1619542.0 -33900.0 -0.06 1798698.0 -132000.0 -0.22 -0.1935 -0.8647 3631552 CBKinase1_021607 COc1cc(NC(=O)CCn2cnc3ccccc3c2=O)c(OC)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M16 compound treatment 1446214.0 -207000.0 -0.35 1737605.0 -193000.0 -0.32 -0.4717 -0.9987 1542636 CBKinase1_021608 CCOC(=O)c1c(NC(=O)CCN2CCC(C)CC2)sc3COC(C)(C)Cc13 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M17 compound treatment 1571697.0 -81700.0 -0.14 1767507.0 -163000.0 -0.27 -0.2869 -0.953 3631553 CBKinase1_021609 O=C(Cn1c(=O)oc2ccccc12)Nc3ccc(cc3)S(=O)(=O)N4CCCC4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M18 compound treatment 1496494.0 -157000.0 -0.27 1804100.0 -127000.0 -0.21 -0.3345 -0.9925 3631554 CBKinase1_021610 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2cc(Cl)cc(Cl)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M19 compound treatment 1492707.0 -161000.0 -0.27 1743281.0 -187000.0 -0.31 -0.4095 -0.9982 3631555 CBKinase1_021611 COc1cccc(c1)C2CC(n3ncc(C(=O)NCc4cccnc4)c3N2)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M20 compound treatment 1573436.0 -80000.0 -0.14 1731690.0 -199000.0 -0.33 -0.3263 -0.9242 3631556 CBKinase1_021612 COC(=O)c1ccccc1NC(=O)CSc2nnnn2c3ccccc3OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M21 compound treatment 1592110.0 -61300.0 -0.1 1717182.0 -213000.0 -0.35 -0.3208 -0.879 3631557 CBKinase1_021613 Cc1onc(c1C(=O)Nc2cccc3nsnc23)c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M22 compound treatment 1361671.0 -292000.0 -0.49 2028294.0 97600.0 0.16 -0.236 -0.4547 1986273 CBKinase1_021614 COc1cc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc(OC)c1OC 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M23 compound treatment 1265632.0 -388000.0 -0.66 1368086.0 -563000.0 -0.92 -1.1161 -0.9861 3631558 CBKinase1_021615 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3cc(Cl)ccc3Oc4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 M24 compound treatment 1282420.0 -371000.0 -0.63 1399075.0 -532000.0 -0.87 -1.0601 -0.9871 3631559 CBKinase1_021616 COc1ccc(cc1OC)c2cc(n3nc(cc3n2)C(=O)N(C)Cc4cnn(C)c4C)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N01 compound treatment 1150997.0 -502000.0 -0.85 1036857.0 -894000.0 -1.46 -1.6371 -0.9666 1788868 CBKinase1_021617 CCOC(=O)c1c(C)c(C)sc1NC(=O)c2nc3ncccn3n2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N02 compound treatment 1103160.0 -550000.0 -0.93 1356976.0 -574000.0 -0.94 -1.3234 -1.0 3631560 CBKinase1_021618 COc1cccc(NC(=O)CSc2nnc(c3ccccc3F)n2c4ccccc4)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N03 compound treatment 1265159.0 -388000.0 -0.66 1314543.0 -616000.0 -1.01 -1.1787 -0.9784 3631561 CBKinase1_021619 CCOC(=O)CCS(=O)(=O)c1nc(cc(n1)C(F)(F)F)c2ccccc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N04 compound treatment 1274577.0 -379000.0 -0.64 1323734.0 -607000.0 -0.99 -1.1568 -0.9775 3631562 CBKinase1_021620 COc1ccc(cc1)N(C(=O)c2cccnc2)S(=O)(=O)c3cccs3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N05 compound treatment 1466188.0 -187000.0 -0.32 1391568.0 -539000.0 -0.88 -0.8488 -0.9043 3631563 CBKinase1_021621 [O-][N+](=O)c1ccccc1OCC(=O)Nc2cccc(Cl)c2N3CCOCC3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N06 compound treatment 1360810.0 -293000.0 -0.5 1397419.0 -533000.0 -0.87 -0.9682 -0.9638 3631564 CBKinase1_021622 Cn1c(SCC(=O)Nc2ccc(cc2)C(=O)N)nnc1c3ccccn3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N07 compound treatment 1584955.0 -68500.0 -0.12 1591591.0 -339000.0 -0.56 -0.4749 -0.8366 3631565 CBKinase1_021623 COc1ccc(cc1NC(=O)COc2ccc(Cl)cc2C)c3cc4ccccc4oc3=O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N08 compound treatment 1482943.0 -170000.0 -0.29 1383337.0 -547000.0 -0.9 -0.8383 -0.8897 3631566 CBKinase1_021624 O=C(CSc1nnc(c2ccccn2)n1c3ccccc3)Nc4ccc5OCCOc5c4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N09 mock treatment 1539273.0 -114000.0 -0.19 1746608.0 -184000.0 -0.3 -0.3499 -0.9768 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N10 mock treatment 1557585.0 -95800.0 -0.16 1736403.0 -194000.0 -0.32 -0.3398 -0.9511 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N11 compound treatment 1514698.0 -139000.0 -0.23 1424996.0 -506000.0 -0.83 -0.752 -0.8731 3631567 CBKinase1_021625 OCc1cc(Cl)ccc1OCC(=O)Nc2ccc(F)cc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N12 compound treatment 1469346.0 -184000.0 -0.31 1677511.0 -253000.0 -0.41 -0.5137 -0.99 3631568 CBKinase1_021626 OC(=O)c1ccc(CSc2nnc(c3cccnc3)n2c4ccc(Br)cc4)cc1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N13 mock treatment 1624682.0 -28700.0 -0.05 1721945.0 -209000.0 -0.34 -0.2763 -0.7996 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N14 mock treatment 1427795.0 -226000.0 -0.38 1494410.0 -436000.0 -0.71 -0.7756 -0.9569 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N15 compound treatment 1553710.0 -99700.0 -0.17 1743538.0 -187000.0 -0.31 -0.3362 -0.9604 3631569 CBKinase1_021627 O=C(CCN1C(=O)c2ccccc2C1=O)NC(=S)Nc3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N16 compound treatment 1467446.0 -186000.0 -0.31 1715367.0 -215000.0 -0.35 -0.4721 -0.9984 3631570 CBKinase1_021628 CNC(=O)CN(c1ccc(Br)c(C)c1)S(=O)(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N17 compound treatment 1286038.0 -367000.0 -0.62 1564990.0 -366000.0 -0.6 -0.8635 -0.9998 3631571 CBKinase1_021629 Clc1cccc(NC(=O)CSc2ncnc3scc(c4ccccc4)c23)c1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N18 compound treatment 1246294.0 -407000.0 -0.69 1573912.0 -357000.0 -0.58 -0.9007 -0.9967 3631572 CBKinase1_021630 FC(F)(F)c1ccccc1NC(=O)Cn2cc(C(=O)c3ccco3)c4ccccc24 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N19 compound treatment 1552397.0 -101000.0 -0.17 1606503.0 -324000.0 -0.53 -0.4966 -0.8898 3631573 CBKinase1_021631 Fc1ccc(cc1)C(=O)CSc2nnc(c3cccnc3)n2c4cccc(c4)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N20 compound treatment 1394039.0 -259000.0 -0.44 1507387.0 -423000.0 -0.69 -0.801 -0.9757 3631574 CBKinase1_021632 CCn1c(SCC(=O)c2cccc(c2)[N+](=O)[O-])nnc1c3ccco3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N21 compound treatment 1418841.0 -235000.0 -0.4 1318138.0 -613000.0 -1.0 -0.9906 -0.9176 3631575 CBKinase1_021633 Fc1ccc(cc1)C(=O)CSc2nnc(c3ccncc3)n2c4cccc(c4)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N22 compound treatment 1277871.0 -376000.0 -0.64 1200505.0 -730000.0 -1.2 -1.2956 -0.9562 3631576 CBKinase1_021634 CC(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2cccc(c2)C(=O)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N23 compound treatment 1330255.0 -323000.0 -0.55 1479498.0 -451000.0 -0.74 -0.9096 -0.989 3631577 CBKinase1_021635 Cc1ccc(cc1)n2c(SCC(=O)Nc3ccc(Br)cc3)nnc2c4cccs4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 N24 compound treatment 1286178.0 -367000.0 -0.62 1201055.0 -730000.0 -1.2 -1.2851 -0.9536 3631578 CBKinase1_021636 [O-][N+](=O)c1cccc(c1)C(=O)CSc2nc(cc(n2)C(F)(F)F)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O01 compound treatment 1048580.0 -605000.0 -1.02 999212.0 -931000.0 -1.53 -1.8034 -0.9811 3631579 CBKinase1_021637 CCn1c(SCC(=O)Nc2ccc(F)c(Cl)c2)nnc1c3ccc(cc3)C(C)(C)C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O02 compound treatment 1301343.0 -352000.0 -0.6 1178227.0 -752000.0 -1.23 -1.2934 -0.9443 3631580 CBKinase1_021638 COc1cccc(NC(=O)C(C)NS(=O)(=O)c2ccc(Br)cc2)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O03 compound treatment 1265307.0 -388000.0 -0.66 906022.0 -1020000.0 -1.68 -1.6519 -0.9161 3631581 CBKinase1_021639 COc1ccccc1C2=NN(C(C2)c3ccco3)C(=O)CCC(=O)O 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O04 compound treatment 1545221.0 -108000.0 -0.18 1143750.0 -787000.0 -1.29 -1.0414 -0.7995 3631582 CBKinase1_021640 CSc1cccc(NC(=O)C(C)NS(=O)(=O)c2ccccc2)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O05 compound treatment 1561919.0 -91500.0 -0.15 1471926.0 -459000.0 -0.75 -0.6411 -0.8352 3631583 CBKinase1_021641 Clc1ccc2nc(NCc3ccccn3)nc(c4ccccc4)c2c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O06 compound treatment 1499105.0 -154000.0 -0.26 1307023.0 -624000.0 -1.02 -0.9074 -0.8602 3631584 CBKinase1_021642 COc1ccc(OC)c(NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O07 compound treatment 1501390.0 -152000.0 -0.26 1127416.0 -803000.0 -1.32 -1.1128 -0.8296 3631585 CBKinase1_021643 COc1ccc(C)cc1S(=O)(=O)N(CC(=O)O)c2ccccc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O08 compound treatment 1551705.0 -102000.0 -0.17 1215615.0 -715000.0 -1.17 -0.9504 -0.8024 3631586 CBKinase1_021644 CS(=O)(=O)N(CC(=O)NC1CCCCC1)c2ccc(Cl)cc2Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O09 compound treatment 1616427.0 -37000.0 -0.06 1308971.0 -622000.0 -1.02 -0.7647 -0.7492 3631587 CBKinase1_021645 COc1ccc(OC)c(c1)S(=O)(=O)N(C)CC(=O)N2CCCCC2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O10 compound treatment 1502497.0 -151000.0 -0.26 1098846.0 -832000.0 -1.36 -1.1446 -0.8253 3631588 CBKinase1_021646 COc1ccc(cc1N(CC(=O)N(C)C)S(=O)(=O)C)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O11 mock treatment 1702461.0 49000.0 0.08 1140158.0 -790000.0 -1.3 -0.8574 -0.6604 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O12 mock treatment 1710247.0 56800.0 0.1 1197263.0 -733000.0 -1.2 -0.7819 -0.6484 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O13 compound treatment 1617303.0 -36100.0 -0.06 1137123.0 -794000.0 -1.3 -0.9628 -0.7395 1542895 CBKinase1_021647 Fc1ccc(NC(=O)Cn2cnc3ccccc3c2=O)c(F)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O14 compound treatment 1748046.0 94600.0 0.16 1280380.0 -650000.0 -1.07 -0.6403 -0.5942 3631589 CBKinase1_021648 COc1cccc(NC(=O)C(C)N(c2ccc(Cl)cc2)S(=O)(=O)C)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O15 compound treatment 1579008.0 -74400.0 -0.13 998169.0 -932000.0 -1.53 -1.1697 -0.7628 3631590 CBKinase1_021649 Cc1sc(NC(=O)CCn2cnc3ccccc3c2=O)c(C#N)c1C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O16 compound treatment 1502473.0 -151000.0 -0.26 1190358.0 -740000.0 -1.21 -1.0386 -0.8377 3631591 CBKinase1_021650 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2cccc(C)c2C 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O17 compound treatment 1600448.0 -53000.0 -0.09 1176453.0 -754000.0 -1.24 -0.9374 -0.7564 3631592 CBKinase1_021651 CCOC(=O)c1c(NC(=O)Cn2c(=O)oc3ccccc23)scc1c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O18 compound treatment 1651429.0 -1990.0 0.0 1134824.0 -796000.0 -1.3 -0.9246 -0.7089 3631593 CBKinase1_021652 COC(=O)c1cc(OC)c(OC)cc1NC(=O)CSc2nc3ccccc3o2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O19 compound treatment 1426174.0 -227000.0 -0.38 1284538.0 -646000.0 -1.06 -1.0208 -0.906 3631594 CBKinase1_021653 COc1cccc(c1)C2CC(n3ncc(C(=O)NCc4ccco4)c3N2)C(F)(F)F 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O20 compound treatment 1670741.0 17300.0 0.03 1241132.0 -690000.0 -1.13 -0.7783 -0.6885 3631595 CBKinase1_021654 O=C(Cn1c(=O)oc2ccccc12)Nc3oc(c(c3C#N)c4ccccc4)c5ccccc5 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O21 compound treatment 1473812.0 -180000.0 -0.3 1106887.0 -824000.0 -1.35 -1.1696 -0.8452 3631596 CBKinase1_021655 Cc1[nH]c2ccc(C)cc2c1CCNC(=O)Nc3ccc(Cl)cc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O22 compound treatment 1464157.0 -189000.0 -0.32 1056884.0 -874000.0 -1.43 -1.2391 -0.8444 3631597 CBKinase1_021656 COC(=O)c1sccc1NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O23 compound treatment 1405856.0 -248000.0 -0.42 1349421.0 -581000.0 -0.95 -0.9699 -0.932 3631598 CBKinase1_021657 COc1ccc(cc1Cl)S(=O)(=O)NCc2ccccn2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 O24 compound treatment 1070096.0 -583000.0 -0.99 1116672.0 -814000.0 -1.33 -1.6415 -0.989 3631599 CBKinase1_021658 NC(=O)c1c(NC(=O)c2cnn3c(cc(nc23)c4ccccc4)C(F)F)sc5CCCc15 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P01 compound treatment 901148.0 -752000.0 -1.27 822425.0 -1110000.0 -1.82 -2.1847 -0.9849 1788884 CBKinase1_021659 CC1CCc2c(C(=O)N)c(NC(=O)c3nc4ncccn4n3)sc2C1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P02 compound treatment 1012119.0 -641000.0 -1.09 954576.0 -976000.0 -1.6 -1.8987 -0.9822 3631600 CBKinase1_021660 Fc1ccccc1c2nnc(SCC(=O)Nc3ccccc3C(F)(F)F)n2c4ccccc4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P03 compound treatment 1453963.0 -199000.0 -0.34 1381872.0 -549000.0 -0.9 -0.8747 -0.9105 3631601 CBKinase1_021661 CC1CCc2c(C(=O)N)c(NC(=O)c3cc4NC(CC(n4n3)C(F)(F)F)c5ccco5)sc2C1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P04 compound treatment 1218308.0 -435000.0 -0.74 1007109.0 -924000.0 -1.51 -1.5911 -0.9452 3631602 CBKinase1_021662 OC(=O)C1CC=CCC1C(=O)Nc2ccc(Br)cc2C(=O)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P05 compound treatment 1332628.0 -321000.0 -0.54 875352.0 -1060000.0 -1.73 -1.6069 -0.8865 3631603 CBKinase1_021663 [O-][N+](=O)c1ccccc1OCC(=O)Nc2cc(c3nc4ccccc4s3)c(Cl)cc2Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P06 compound treatment 1251703.0 -402000.0 -0.68 894335.0 -1040000.0 -1.7 -1.6818 -0.9193 3631604 CBKinase1_021664 Cn1c(SCC(=O)Nc2ccc(Oc3ccccc3)cc2)nnc1c4ccccn4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P07 compound treatment 1182877.0 -471000.0 -0.8 991182.0 -939000.0 -1.54 -1.6519 -0.9529 3631605 CBKinase1_021665 Cc1ccccc1OCC(=O)Nc2cc(c3nc4ccccc4s3)c(Cl)cc2Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P08 compound treatment 1202770.0 -451000.0 -0.76 1026286.0 -904000.0 -1.48 -1.5874 -0.9523 3631606 CBKinase1_021666 CC(C)OC(=O)CSc1nnc(c2ccccn2)n1c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P09 compound treatment 1355888.0 -298000.0 -0.5 1052572.0 -878000.0 -1.44 -1.3737 -0.901 3631607 CBKinase1_021667 OCc1ccc(o1)c2cccc(NC(=S)NC(=O)c3cc4ccccc4o3)c2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P10 compound treatment 1370171.0 -283000.0 -0.48 1099201.0 -831000.0 -1.36 -1.3026 -0.9017 3631608 CBKinase1_021668 Cn1c(SCC(=O)Nc2ccc3OCCOc3c2)nnc1c4cnccn4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P11 mock treatment 1464832.0 -189000.0 -0.32 1130983.0 -800000.0 -1.31 -1.1524 -0.8544 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P12 mock treatment 1549854.0 -104000.0 -0.18 1696604.0 -234000.0 -0.38 -0.3952 -0.9371 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P13 compound treatment 1496811.0 -157000.0 -0.27 1326766.0 -604000.0 -0.99 -0.8873 -0.866 3631609 CBKinase1_021669 COc1ccccc1NC(=O)C(C)NS(=O)(=O)c2ccccc2 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P14 compound treatment 1128024.0 -525000.0 -0.89 940885.0 -990000.0 -1.62 -1.7759 -0.96 3631610 CBKinase1_021670 FC(F)(F)c1cc(nc(SCC(=O)Nc2cccc(Cl)c2Cl)n1)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P15 compound treatment 1353666.0 -300000.0 -0.51 880663.0 -1050000.0 -1.72 -1.5756 -0.8782 3631611 CBKinase1_021671 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2cc3ccccc3oc2=O)c1 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P16 compound treatment 1198187.0 -455000.0 -0.77 964515.0 -966000.0 -1.58 -1.6645 -0.9452 3631612 CBKinase1_021672 CC(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2cc(ccc2C)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P17 compound treatment 1306839.0 -347000.0 -0.59 1133079.0 -798000.0 -1.31 -1.3391 -0.9347 3631613 CBKinase1_021673 COc1ccc(NC(=O)CSc2ncnc3sc(cc23)c4ccccc4)c(c1)[N+](=O)[O-] 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P18 compound treatment 1064518.0 -589000.0 -1.0 887326.0 -1040000.0 -1.71 -1.9139 -0.967 3631614 CBKinase1_021674 Cc1ccc(NC(=O)Cn2cc(C(=O)c3cccs3)c4ccccc24)cc1Cl 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P19 compound treatment 1178461.0 -475000.0 -0.8 1027417.0 -903000.0 -1.48 -1.6152 -0.9589 3631615 CBKinase1_021675 CCOC(=O)c1c(C)c(C)sc1NC(=O)c2ccc(C)c(c2)S(=O)(=O)N3CCCCCC3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P20 compound treatment 1236879.0 -417000.0 -0.71 929384.0 -1000000.0 -1.64 -1.6589 -0.9288 3631616 CBKinase1_021676 COC(=O)c1ccccc1NC(=O)c2ccc(cc2)N(C)S(=O)(=O)c3ccc(OC)c(OC)c3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P21 compound treatment 1269557.0 -384000.0 -0.65 1025061.0 -906000.0 -1.48 -1.5089 -0.9313 3631617 CBKinase1_021677 COc1ccc(cc1)n2c(SCC(=O)Nc3ccc(F)cc3F)nnc2c4ccco4 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P22 compound treatment 1147108.0 -506000.0 -0.86 959375.0 -971000.0 -1.59 -1.7316 -0.9578 3631618 CBKinase1_021678 FC(F)(F)c1cc(nc(SCC(=O)c2ccccc2)n1)c3ccccc3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P23 compound treatment 1225541.0 -428000.0 -0.72 1111957.0 -819000.0 -1.34 -1.4609 -0.9581 3631619 CBKinase1_021679 Cc1ccc(cc1)n2c(SCC(=O)N)nnc2c3cccs3 1010.0040 DAPIStaining(1010.0040) PlasmodiumViabilityAssay 1010.0040.2391 P24 compound treatment 969707.0 -684000.0 -1.16 939622.0 -991000.0 -1.62 -1.9668 -0.9862 3631620 CBKinase1_021680 Fc1ccc(NC(=O)CSc2nnc([nH]2)c3ccco3)cc1