ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A01 compound treatment 1172286.0 -343000.0 -0.64 1321013.0 -93200.0 -0.19 -0.5877 -0.8756 3629228 CBKinase1_019121 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2ccccc2N(C)S(=O)(=O)C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A02 compound treatment 832286.0 -683000.0 -1.28 1153665.0 -261000.0 -0.52 -1.2755 -0.9211 3629229 CBKinase1_019122 Cc1c(NC(=O)CN(c2ccccc2F)S(=O)(=O)C)cccc1[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A03 compound treatment 1301508.0 -214000.0 -0.4 963185.0 -451000.0 -0.9 -0.9218 -0.9339 3629230 CBKinase1_019123 COc1ccc(Cl)cc1NC(=O)CC(N2CCNCC2)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A04 compound treatment 1362395.0 -153000.0 -0.29 1060893.0 -353000.0 -0.71 -0.7029 -0.9217 3629231 CBKinase1_019124 O=C(CC1N(C2CCCCC2NC1=O)C(=O)Nc3ccccc3)Nc4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A05 compound treatment 973636.0 -542000.0 -1.02 676164.0 -738000.0 -1.48 -1.7627 -0.9836 3629232 CBKinase1_019125 COc1ccc(OC)c(c1)N(CC(=O)Nc2ccc(Br)c(Cl)c2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A06 compound treatment 902741.0 -613000.0 -1.15 948466.0 -466000.0 -0.93 -1.472 -0.9945 3629233 CBKinase1_019126 CS(=O)(=O)N(CC(=O)Nc1ccc(Br)cc1F)c2ccc(Cl)c(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A07 compound treatment 994239.0 -522000.0 -0.98 689561.0 -725000.0 -1.45 -1.7164 -0.9818 3629234 CBKinase1_019127 COc1ccc(Cn2c(nc3ccccc23)c4nonc4NC(=O)C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A08 compound treatment 1038622.0 -477000.0 -0.9 941702.0 -473000.0 -0.94 -1.3012 -0.9997 3629235 CBKinase1_019128 CS(=O)(=O)N(CC(=O)Nc1c(F)cccc1F)c2cccc(c2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A09 compound treatment 976916.0 -539000.0 -1.01 982369.0 -432000.0 -0.86 -1.3256 -0.9969 3629236 CBKinase1_019129 CC(=O)c1cccc(NC(=O)C2CCCN(C2)S(=O)(=O)c3ccc(Cl)cc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A10 compound treatment 835062.0 -681000.0 -1.28 824344.0 -590000.0 -1.18 -1.7372 -0.9992 3629237 CBKinase1_019130 Cc1cccc(c1)c2nnc(SCC(=O)Nc3cc(ccc3C)[N+](=O)[O-])n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A11 compound treatment 1014591.0 -501000.0 -0.94 837875.0 -576000.0 -1.15 -1.4798 -0.995 3629238 CBKinase1_019131 COc1ccc(cc1Cl)N(CC(=O)Nc2c(F)cccc2F)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A12 compound treatment 952730.0 -563000.0 -1.06 1174895.0 -239000.0 -0.48 -1.0856 -0.9357 3629239 CBKinase1_019132 Cc1c(CCC(=O)O)c(=O)oc2cc(OCc3cccc(F)c3)ccc12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A13 mock treatment 1183168.0 -333000.0 -0.62 977229.0 -437000.0 -0.87 -1.0591 -0.9865 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A14 mock treatment 1103937.0 -412000.0 -0.77 813656.0 -601000.0 -1.2 -1.3954 -0.9774 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A15 compound treatment 950310.0 -565000.0 -1.06 1039001.0 -375000.0 -0.75 -1.2809 -0.9855 3629240 CBKinase1_019133 COC(=O)c1cc(NC(=O)CSc2nnc(C)s2)ccc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A16 compound treatment 1163965.0 -352000.0 -0.66 889652.0 -525000.0 -1.05 -1.2083 -0.9752 3629241 CBKinase1_019134 CC(NS(=O)(=O)c1ccc(C)cc1)C(=O)Nc2c(C)cc(C)cc2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A17 compound treatment 936442.0 -579000.0 -1.09 771362.0 -643000.0 -1.28 -1.6775 -0.9966 3629242 CBKinase1_019135 CC(Sc1nc(O)c(c2ccccc2)c(=O)[nH]1)C(=O)Nc3cccc(Cl)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A18 compound treatment 1185692.0 -330000.0 -0.62 1094606.0 -320000.0 -0.64 -0.8898 -0.9999 3629243 CBKinase1_019136 COc1cccc(c1)N(CC(=O)Nc2ccc(cc2)C(F)(F)F)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A19 compound treatment 1051796.0 -464000.0 -0.87 783313.0 -631000.0 -1.26 -1.5075 -0.9837 3629244 CBKinase1_019137 CSc1ccccc1NC(=O)CN(c2ccc(Br)cc2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A20 compound treatment 1140622.0 -375000.0 -0.7 715945.0 -698000.0 -1.4 -1.4848 -0.9498 3629245 CBKinase1_019138 COc1ccc(cc1OC)N(CC(=O)Nc2ccc(Cl)c(Cl)c2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A21 compound treatment 1153434.0 -362000.0 -0.68 875379.0 -539000.0 -1.08 -1.2425 -0.9754 3629246 CBKinase1_019139 Clc1cccc(NC(=O)CC2N(CCNC2=O)C(=O)Nc3ccccc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A22 compound treatment 823244.0 -693000.0 -1.3 758762.0 -655000.0 -1.31 -1.8456 -1.0 3629247 CBKinase1_019140 CC(C)c1ccc(cc1)C2N(CCCN3CCOCC3)C(=O)c4oc5ccc(Cl)cc5c(=O)c24 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A23 compound treatment 928321.0 -587000.0 -1.1 930841.0 -483000.0 -0.97 -1.4629 -0.9978 3629248 CBKinase1_019141 O=C(COc1ccc(cc1)c2ccc(C#N)cc2)Nc3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 A24 compound treatment 977455.0 -538000.0 -1.01 643799.0 -770000.0 -1.54 -1.8034 -0.9791 3629249 CBKinase1_019142 COc1cc(ccc1NC(=S)Nc2cccc(Cn3nc(C)c(Br)c3C)c2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B01 compound treatment 1113091.0 -403000.0 -0.76 823918.0 -590000.0 -1.18 -1.3688 -0.9769 3629250 CBKinase1_019143 CC(Oc1ccc(Br)cc1)c2nc(no2)c3ccccn3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B02 compound treatment 1388051.0 -128000.0 -0.24 1178050.0 -236000.0 -0.47 -0.5033 -0.9507 3629251 CBKinase1_019144 Cc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)NCc3ccccn3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B03 compound treatment 1358309.0 -157000.0 -0.3 1291389.0 -123000.0 -0.25 -0.3826 -0.9957 3629252 CBKinase1_019145 COc1cc(NC(=O)COc2ccc(cc2)[N+](=O)[O-])cc(OC)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B04 compound treatment 1151350.0 -364000.0 -0.68 981464.0 -433000.0 -0.86 -1.0953 -0.9933 3629253 CBKinase1_019146 COC(=O)c1cc(C)sc1NC(=S)Nc2ncn(Cc3ccc(F)cc3Cl)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B05 compound treatment 1000551.0 -515000.0 -0.97 1238449.0 -176000.0 -0.35 -0.9323 -0.906 3629254 CBKinase1_019147 COC(=O)c1cccc(COC(=O)c2ccc(NC(=O)c3ccccc3)cc2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B06 compound treatment 989448.0 -526000.0 -0.99 887206.0 -527000.0 -1.05 -1.4435 -0.9995 3629255 CBKinase1_019148 COC(=O)c1cccc(NC(=O)COc2ccc(OC)cc2)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B07 compound treatment 1106175.0 -410000.0 -0.77 1144667.0 -270000.0 -0.54 -0.9246 -0.9849 3629256 CBKinase1_019149 CC(C)c1ccccc1NC(=O)CCCN2C(=O)c3ccccc3C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B08 compound treatment 917968.0 -598000.0 -1.12 833666.0 -581000.0 -1.16 -1.614 -0.9999 3629257 CBKinase1_019150 [O-][N+](=O)c1cccc(NC(=O)Nc2nn(Cc3ccc(Cl)c(Cl)c3)cc2Cl)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B09 compound treatment 1020384.0 -495000.0 -0.93 1076807.0 -337000.0 -0.67 -1.1344 -0.9875 3629258 CBKinase1_019151 Cc1c(NC(=O)COc2ccccc2Cl)cccc1C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B10 compound treatment 1178142.0 -338000.0 -0.63 1070056.0 -344000.0 -0.69 -0.9346 -0.9992 3629259 CBKinase1_019152 OC(=O)C(CC(=O)Nc1cccc(c1)[N+](=O)[O-])N2CCCCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B11 compound treatment 1104404.0 -411000.0 -0.77 1333521.0 -80700.0 -0.16 -0.6601 -0.8367 3629260 CBKinase1_019153 O=C(NCc1ccco1)c2ccc3C(=O)N(Cc4cccnc4)C(=O)c3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B12 compound treatment 1123400.0 -392000.0 -0.74 1057893.0 -356000.0 -0.71 -1.0244 -0.9999 3629261 CBKinase1_019154 COc1ccc(CCNC(=O)C(=O)Nc2ccc(cc2)C(C)(C)C)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B13 mock treatment 1265896.0 -250000.0 -0.47 1252453.0 -162000.0 -0.32 -0.5603 -0.9835 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B14 mock treatment 1118722.0 -397000.0 -0.75 939460.0 -475000.0 -0.95 -1.198 -0.9929 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B15 compound treatment 1365624.0 -150000.0 -0.28 832381.0 -582000.0 -1.16 -1.0216 -0.8538 3211646 CBKinase1_019155 CCOC(=O)COc1ccc(cc1)c2nnn[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B16 compound treatment 1228355.0 -287000.0 -0.54 909240.0 -505000.0 -1.01 -1.0952 -0.957 3629262 CBKinase1_019156 FC(F)(F)Oc1ccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccccc4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B17 compound treatment 1268068.0 -248000.0 -0.46 976471.0 -438000.0 -0.87 -0.9474 -0.9563 3629263 CBKinase1_019157 COC(=O)c1c(NC(=S)Nc2ccn(C)n2)sc3CCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B18 compound treatment 1063842.0 -452000.0 -0.85 863968.0 -550000.0 -1.1 -1.3775 -0.9918 3629264 CBKinase1_019158 CCOC(=O)c1c(NC(=S)Nc2nc(C)cc(C)n2)sc3CCCCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B19 compound treatment 1046886.0 -469000.0 -0.88 1112617.0 -302000.0 -0.6 -1.0486 -0.9829 3629265 CBKinase1_019159 COC(=O)c1cc(sc1NC(=S)NC(C)c2cc(OC)ccc2OC)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B20 compound treatment 1075377.0 -440000.0 -0.83 983764.0 -430000.0 -0.86 -1.1929 -0.9998 3629266 CBKinase1_019160 COC(=O)c1c(NC(=S)NCc2ccccn2)sc(C)c1c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B21 compound treatment 1039818.0 -476000.0 -0.89 857126.0 -557000.0 -1.11 -1.4191 -0.994 3629267 CBKinase1_019161 CCn1cc(CNC(=S)Nc2cc(OC)ccc2OC)cn1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B22 compound treatment 1082024.0 -434000.0 -0.81 1192166.0 -222000.0 -0.44 -0.8896 -0.9593 3629268 CBKinase1_019162 O=C(C1c2ccccc2Oc3ccccc13)N(CCC#N)CCC#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B23 compound treatment 928431.0 -587000.0 -1.1 1087818.0 -326000.0 -0.65 -1.2409 -0.9686 3629269 CBKinase1_019163 CCOC(=O)c1c(NC(=O)CN2C(=O)COc3ccc(Cl)cc23)sc4CCCCc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 B24 compound treatment 1266177.0 -250000.0 -0.47 983899.0 -430000.0 -0.86 -0.9395 -0.9592 3629270 CBKinase1_019164 Cc1cc(ccc1NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C01 compound treatment 1846019.0 330000.0 0.62 1531384.0 117000.0 0.23 0.604 0.9114 3629271 CBKinase1_019165 COc1ccc(cc1Cl)N(CC(=O)Nc2ccc(Br)c(Cl)c2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C02 compound treatment 1770659.0 255000.0 0.48 1411216.0 -2990.0 -0.01 0.3342 0.6982 3629272 CBKinase1_019166 Cc1ccc(cc1NC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)C)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C03 compound treatment 1745177.0 229000.0 0.43 1606527.0 192000.0 0.38 0.5764 0.9984 3629273 CBKinase1_019167 COc1cccc(Cn2cc(NC(=O)Nc3ccc(F)cc3F)cn2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C04 compound treatment 1775653.0 260000.0 0.49 1736549.0 322000.0 0.64 0.8006 0.9906 2068000 CBKinase1_019168 OC(=O)C(CC(=O)Nc1ccccc1)N2CCCCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C05 compound treatment 1858907.0 343000.0 0.64 1710586.0 296000.0 0.59 0.8744 0.9991 3629274 CBKinase1_019169 COc1cc(ccc1NC(=S)Nc2cccc(Cn3cc(Cl)cn3)c2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C06 compound treatment 1943644.0 428000.0 0.8 1662671.0 248000.0 0.5 0.9192 0.9733 3629275 CBKinase1_019170 COc1ccc(cc1)N(C(C)C(=O)Nc2ccc(cc2)C(F)(F)F)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C07 compound treatment 2034541.0 519000.0 0.97 1550429.0 136000.0 0.27 0.8812 0.8714 3629276 CBKinase1_019171 O=C(N(CCC#N)CCC#N)c1ccccc1Oc2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C08 compound treatment 2041755.0 526000.0 0.99 1427839.0 13600.0 0.03 0.7175 0.7263 3629277 CBKinase1_019172 CC(C)Cc1nnc(SC(C)C(=O)Nc2cccc(Cl)c2)[nH]1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C09 compound treatment 2107240.0 591000.0 1.11 1643958.0 230000.0 0.46 1.1099 0.9237 3629278 CBKinase1_019173 COC(=O)c1c(NC(=S)Nc2cn(C)nc2C(=O)N)sc3CCCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C10 compound treatment 1728298.0 213000.0 0.4 1508221.0 94000.0 0.19 0.415 0.941 3629279 CBKinase1_019174 CCOC(=O)c1c(NC(=O)c2ccccc2N(C)S(=O)(=O)C)sc3CCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C11 mock treatment 1958153.0 442000.0 0.83 1763218.0 349000.0 0.7 1.0805 0.9962 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C12 mock treatment 2102859.0 587000.0 1.1 1675987.0 262000.0 0.52 1.1493 0.942 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C13 compound treatment 2081487.0 566000.0 1.06 1866204.0 452000.0 0.9 1.3898 0.9968 3629280 CBKinase1_019175 COC(=O)c1c(NC(=S)NCCn2cc(Br)cn2)sc3CC(C)CCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C14 compound treatment 1249049.0 -267000.0 -0.5 696162.0 -718000.0 -1.44 -1.3688 -0.9006 3629281 CBKinase1_019176 COc1cc(C)c(cc1S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2)C(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C15 mock treatment 1786767.0 271000.0 0.51 1624180.0 210000.0 0.42 0.6565 0.9954 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C16 mock treatment 2165020.0 649000.0 1.22 1599145.0 185000.0 0.37 1.1233 0.8819 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C17 compound treatment 2025145.0 509000.0 0.96 1515421.0 101000.0 0.2 0.8193 0.8381 3629282 CBKinase1_019177 Cc1cc(NC(=O)C(=O)NCCCn2ccnc2)ccc1Br 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C18 compound treatment 2251563.0 736000.0 1.38 1371946.0 -42300.0 -0.08 0.9171 0.6626 3629283 CBKinase1_019178 CN(c1ccccc1C(=O)NCc2ccco2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C19 compound treatment 1759687.0 244000.0 0.46 1745321.0 331000.0 0.66 0.7918 0.9838 3629284 CBKinase1_019179 COc1ccc(cc1)C(=O)n2nc(nc2NCc3ccco3)c4ccc(Cl)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C20 compound treatment 2009217.0 493000.0 0.93 1507300.0 93100.0 0.19 0.7866 0.8325 3629285 CBKinase1_019180 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Cl)c2cccc(c2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C21 compound treatment 1827253.0 312000.0 0.58 1804772.0 391000.0 0.78 0.9655 0.9899 3629286 CBKinase1_019181 Cc1nn(C)c(C)c1NC(=S)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C22 compound treatment 1851166.0 335000.0 0.63 1541570.0 127000.0 0.25 0.6253 0.9206 3629287 CBKinase1_019182 CS(=O)(=O)N(CC(=O)Nc1ccc(F)c(F)c1)c2cccc(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C23 compound treatment 1602761.0 87000.0 0.16 1735732.0 322000.0 0.64 0.5699 0.8595 3629288 CBKinase1_019183 CC(C)CNc1nc(Oc2ccc(O)nn2)nc(n1)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 C24 compound treatment 1961730.0 446000.0 0.84 1428779.0 14600.0 0.03 0.6126 0.7313 3629289 CBKinase1_019184 COC(=O)c1cc(OC)c(OC)cc1NC(=O)Cn2nnc(n2)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D01 compound treatment 1486159.0 -29600.0 -0.06 1206020.0 -208000.0 -0.42 -0.3335 -0.7945 3629290 CBKinase1_019185 CS(=O)(=O)CCC(N1C(=O)c2cc(Cl)c(Cl)cc2C1=O)C(=O)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D02 compound treatment 1513073.0 -2680.0 -0.01 1459327.0 45100.0 0.09 0.0602 0.6666 3629291 CBKinase1_019186 COc1cc(cc(Br)c1O)C2N(CCCN3CCOCC3)C(=O)c4oc5ccc(Cl)cc5c(=O)c24 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D03 compound treatment 1492626.0 -23100.0 -0.04 1644417.0 230000.0 0.46 0.2947 0.6376 3629292 CBKinase1_019187 Oc1nc2ccccc2nc1CCC(=O)OCc3c(F)cccc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D04 compound treatment 1671544.0 156000.0 0.29 1848216.0 434000.0 0.87 0.8202 0.896 3629293 CBKinase1_019188 CC(NS(=O)(=O)c1ccccc1)C(=O)Nc2cccc(C)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D05 compound treatment 1406561.0 -109000.0 -0.2 1404115.0 -10100.0 -0.02 -0.1592 -0.7729 3629294 CBKinase1_019189 COc1cc(NC(=O)C(C)Oc2ccc(Cl)cc2Cl)ccc1NC(=O)c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D06 compound treatment 1763889.0 248000.0 0.47 1751482.0 337000.0 0.67 0.8061 0.9837 3629295 CBKinase1_019190 CC(C)c1ccc(cc1)S(=O)(=O)Nc2ccc(O)c(Sc3nc[nH]n3)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D07 compound treatment 1732837.0 217000.0 0.41 1640391.0 226000.0 0.45 0.6078 0.9987 3629296 CBKinase1_019191 COc1cc2c(cc1NC(=O)C(C)Oc3ccc(Br)cc3)oc4ccccc42 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D08 compound treatment 1681328.0 166000.0 0.31 1672751.0 259000.0 0.52 0.5852 0.9704 1641496 CBKinase1_019192 COc1ccc(CCNC(=S)N2CCN(CC2)c3ncccn3)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D09 compound treatment 1859659.0 344000.0 0.65 1729095.0 315000.0 0.63 0.9016 0.9999 3629297 CBKinase1_019193 OC(=O)CCC(=O)Nc1ccc(NC(=O)c2cccs2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D10 compound treatment 1738756.0 223000.0 0.42 1588151.0 174000.0 0.35 0.5419 0.9957 3629298 CBKinase1_019194 Cn1nnnc1SCC(=O)Nc2ccc(N3CCOCC3)c(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D11 mock treatment 1852816.0 337000.0 0.63 1810646.0 396000.0 0.79 1.0077 0.9938 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D12 mock treatment 1898195.0 382000.0 0.72 1931839.0 518000.0 1.03 1.2392 0.9841 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D13 compound treatment 1582583.0 66800.0 0.13 1836446.0 422000.0 0.84 0.6855 0.8034 3629299 CBKinase1_019195 COc1ccc(CCNC(=O)c2cc3cc(F)ccc3nc2C)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D14 compound treatment 1760446.0 245000.0 0.46 1925304.0 511000.0 1.02 1.0472 0.9349 3629300 CBKinase1_019196 CCCOc1ccc(Oc2nc(NC(C)(C)C)nc(n2)N3CCOCC3)nn1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D15 mock treatment 1748411.0 233000.0 0.44 1654373.0 240000.0 0.48 0.6483 0.9989 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D16 mock treatment 1886478.0 371000.0 0.7 1652001.0 238000.0 0.48 0.8282 0.9827 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D17 compound treatment 1982895.0 467000.0 0.88 1595397.0 181000.0 0.36 0.8762 0.9235 1664661 CBKinase1_019197 O=C(CSc1ncn[nH]1)N(c2ccccc2)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D18 compound treatment 1732698.0 217000.0 0.41 1572710.0 159000.0 0.32 0.512 0.9923 3629301 CBKinase1_019198 Cc1nnc(SCC(=O)Nc2ccc(F)c(F)c2F)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D19 compound treatment 1766850.0 251000.0 0.47 1693835.0 280000.0 0.56 0.7285 0.9964 3629302 CBKinase1_019199 COc1ccccc1NC(=O)CC2N(CCNC2=O)C(=O)Nc3ccc(Cl)c(Cl)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D20 compound treatment 1362275.0 -153000.0 -0.29 1276401.0 -138000.0 -0.28 -0.3985 -0.9997 3629303 CBKinase1_019200 COc1c(Cl)cc(cc1Cl)C(=O)Nc2sc3CCCCc3c2C(=O)NCc4cccnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D21 compound treatment 1543172.0 27400.0 0.05 1559479.0 145000.0 0.29 0.2417 0.8197 3629304 CBKinase1_019201 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccccc3)S(=O)(=O)c4cccs4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D22 compound treatment 1423481.0 -92300.0 -0.17 1678790.0 265000.0 0.53 0.2514 0.4519 3629305 CBKinase1_019202 CCn1c2nnc(SCCOc3ccc(C)cc3)n2c4ccccc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D23 compound treatment 1448572.0 -67200.0 -0.13 1642502.0 228000.0 0.46 0.2335 0.4932 3629306 CBKinase1_019203 COc1cc(ccc1NC(=S)NCc2cccnc2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 D24 compound treatment 1708410.0 193000.0 0.36 1593522.0 179000.0 0.36 0.5092 1.0 3629307 CBKinase1_019204 CS(=O)(=O)N(CC(=O)Nc1ccc(Br)c(Cl)c1)c2cccc(c2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E01 mock treatment 1558551.0 42800.0 0.08 964801.0 -449000.0 -0.9 -0.5783 -0.6413 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E02 mock treatment 1721071.0 205000.0 0.39 1175777.0 -238000.0 -0.48 -0.0644 -0.1051 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E03 compound treatment 1616938.0 101000.0 0.19 1480449.0 66200.0 0.13 0.2279 0.9844 3629308 CBKinase1_019205 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Cl)c2ccc(Oc3ccccc3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E04 compound treatment 1620096.0 104000.0 0.2 1306137.0 -108000.0 -0.22 -0.0142 -0.0488 3629309 CBKinase1_019206 COc1ccc(Cl)cc1NC(=S)NCCn2cc(Br)cn2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E05 compound treatment 1170742.0 -345000.0 -0.65 1236052.0 -178000.0 -0.36 -0.7098 -0.9603 3629310 CBKinase1_019207 Clc1ccc(cc1S(=O)(=O)N2CCOCC2)C(=O)NCc3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E06 compound treatment 1618524.0 103000.0 0.19 1231480.0 -183000.0 -0.37 -0.1218 -0.2949 3629311 CBKinase1_019208 COC(=O)c1ccccc1NC(=O)CSc2nnc([nH]2)c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E07 compound treatment 1602505.0 86800.0 0.16 1457325.0 43100.0 0.09 0.1761 0.9557 3629312 CBKinase1_019209 CS(=O)(=O)N(CC(=O)Nc1ccc(Cl)c(Cl)c1)c2ccccc2F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E08 compound treatment 1443726.0 -72000.0 -0.14 1235495.0 -179000.0 -0.36 -0.3482 -0.9117 3629313 CBKinase1_019210 Clc1ccc(cc1)N2CC(CC2=O)C(=O)Nc3ccccc3C(=O)NCc4ccco4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E09 mock treatment 1612336.0 96600.0 0.18 1275670.0 -139000.0 -0.28 -0.0676 -0.2042 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E10 mock treatment 1490431.0 -25300.0 -0.05 1414874.0 668.0 0.0 -0.0327 -0.687 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E11 compound treatment 1440122.0 -75600.0 -0.14 1484040.0 69800.0 0.14 -0.0017 -0.0086 3629314 CBKinase1_019211 COc1ccc(c(C)c1C)S(=O)(=O)NCc2ccccn2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E12 compound treatment 1714632.0 199000.0 0.37 1430598.0 16400.0 0.03 0.2872 0.7662 3629315 CBKinase1_019212 Clc1cc(Cl)cc(NC(=O)CC2OCCN(Cc3ccccc3)C2=O)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E13 compound treatment 1563931.0 48200.0 0.09 1474270.0 60100.0 0.12 0.1488 0.9903 3629316 CBKinase1_019213 COc1ccc(Cl)cc1NC(=O)CSc2nnc(c3ccccc3)n2c4ccc(C)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E14 compound treatment 1551934.0 36200.0 0.07 1394784.0 -19400.0 -0.04 0.0206 0.2631 3629317 CBKinase1_019214 COc1cccc(NC(=O)C(C)NS(=O)(=O)c2ccc(Cl)cc2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E15 compound treatment 1630455.0 115000.0 0.22 1221605.0 -193000.0 -0.38 -0.1199 -0.2719 3629318 CBKinase1_019215 COC(=O)c1c(NC(=S)Nc2ccn(C)n2)sc3CCCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E16 compound treatment 984034.0 -532000.0 -1.0 928462.0 -486000.0 -0.97 -1.3923 -0.9999 3629319 CBKinase1_019216 CCOc1ccc2nc(Nc3nc(C)c(CCC(C)C)c(=O)[nH]3)nc(C)c2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E17 mock treatment 1731132.0 215000.0 0.4 1287130.0 -127000.0 -0.25 0.1063 0.2227 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E18 mock treatment 1589985.0 74200.0 0.14 1297108.0 -117000.0 -0.23 -0.0669 -0.2458 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E19 compound treatment 1315907.0 -200000.0 -0.38 1505612.0 91400.0 0.18 -0.1361 -0.3262 3629320 CBKinase1_019217 O=C(CCc1ccccc1)Nc2ccccc2C(=O)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E20 compound treatment 1032387.0 -483000.0 -0.91 1028726.0 -385000.0 -0.77 -1.1865 -0.9967 3629321 CBKinase1_019218 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3cccc(c3)C(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E21 compound treatment 1459218.0 -56500.0 -0.11 1536019.0 122000.0 0.24 0.0971 0.3656 3629322 CBKinase1_019219 CCc1c(O)nc(SCC(=O)N(c2ccccc2)c3ccccc3)[nH]c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E22 compound treatment 1385690.0 -130000.0 -0.24 1458257.0 44100.0 0.09 -0.1104 -0.4253 3118574 CBKinase1_019220 Clc1cccc(NC(=O)CC2N(CCNC2=O)C(=O)c3ccccc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E23 compound treatment 1458728.0 -57000.0 -0.11 1259487.0 -155000.0 -0.31 -0.2944 -0.8995 3629323 CBKinase1_019221 CS(=O)(=O)N(CC(=O)Nc1ccccc1C(=O)N2CCOCC2)c3cccc(Cl)c3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 E24 compound treatment 1304847.0 -211000.0 -0.4 608080.0 -806000.0 -1.61 -1.4193 -0.8554 3629324 CBKinase1_019222 CCCCc1ccc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F01 mock treatment 1420606.0 -95100.0 -0.18 1506701.0 92500.0 0.18 0.0044 0.0172 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F02 mock treatment 1349507.0 -166000.0 -0.31 1669939.0 256000.0 0.51 0.1407 0.235 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F03 compound treatment 1391880.0 -124000.0 -0.23 1588016.0 174000.0 0.35 0.0812 0.1942 3629325 CBKinase1_019223 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2ccccc2c3nc4ccccc4s3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F04 compound treatment 1273878.0 -242000.0 -0.45 1118825.0 -295000.0 -0.59 -0.7385 -0.9916 3629326 CBKinase1_019224 CS(=O)(=O)N(CC(=O)Nc1ccc(Cl)c(Cl)c1)c2ccc(Br)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F05 compound treatment 599367.0 -916000.0 -1.72 609427.0 -805000.0 -1.61 -2.3539 -0.9994 3629327 CBKinase1_019225 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2cc(ccc2N3CCOCC3)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F06 compound treatment 1600287.0 84500.0 0.16 1739882.0 326000.0 0.65 0.5725 0.8545 3629328 CBKinase1_019226 COC(=O)c1ccc(C(=O)OC)c(NS(=O)(=O)c2ccc3OCCOc3c2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F07 compound treatment 1491897.0 -23900.0 -0.04 1670474.0 256000.0 0.51 0.3305 0.6428 3629329 CBKinase1_019227 COc1cccc(OCC(=O)Nc2cccc(C(=O)O)c2C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F08 compound treatment 1274752.0 -241000.0 -0.45 1700299.0 286000.0 0.57 0.0844 0.1158 3629330 CBKinase1_019228 CC(C)(C)C1CCc2c(C#N)c(NC(=O)CSc3nnc([nH]3)c4ccco4)sc2C1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F09 mock treatment 1662157.0 146000.0 0.27 1785115.0 371000.0 0.74 0.7185 0.9088 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F10 mock treatment 1468390.0 -47400.0 -0.09 1672188.0 258000.0 0.52 0.3017 0.5767 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F11 compound treatment 1518233.0 2480.0 0.0 1827200.0 413000.0 0.83 0.587 0.7111 3629331 CBKinase1_019229 O=C1N(CCCc2nc(no2)c3ccncc3)C(=O)c4ccccc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F12 compound treatment 1444950.0 -70800.0 -0.13 1915116.0 501000.0 1.0 0.6139 0.6079 3629332 CBKinase1_019230 CCn1ncc(NC(=S)NCc2ccco2)c1C(=O)N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F13 compound treatment 1564985.0 49200.0 0.09 1591526.0 177000.0 0.35 0.316 0.8627 3629333 CBKinase1_019231 COc1cccc(NC(=O)CSc2nnc(c3cccc(C)c3)n2c4ccccc4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F14 compound treatment 1547441.0 31700.0 0.06 1714552.0 300000.0 0.6 0.4665 0.7734 3629334 CBKinase1_019232 COc1ccc(cc1c2nnc3c4ccccc4c(C)nn23)S(=O)(=O)NCc5ccco5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F15 compound treatment 1548713.0 33000.0 0.06 1718977.0 305000.0 0.61 0.4745 0.7749 3629335 CBKinase1_019233 COC(=O)c1cc(C)sc1NC(=S)NC(C)c2cn(C)nc2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F16 compound treatment 1325668.0 -190000.0 -0.36 1591888.0 178000.0 0.36 -0.0012 -0.0024 3629336 CBKinase1_019234 COc1ccc(OC)c(NC(=O)Cc2c(OC)ccc3cc(Br)ccc23)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F17 mock treatment 1527917.0 12200.0 0.02 1618902.0 205000.0 0.41 0.3054 0.7454 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F18 mock treatment 1434591.0 -81200.0 -0.15 1447091.0 32900.0 0.07 -0.0613 -0.3692 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F19 compound treatment 1245131.0 -271000.0 -0.51 1654004.0 240000.0 0.48 -0.0203 -0.0291 3629337 CBKinase1_019235 CN(c1ccccc1C(=O)NCC2CCCO2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F20 compound treatment 1274449.0 -241000.0 -0.45 1458623.0 44400.0 0.09 -0.2576 -0.5579 3629338 CBKinase1_019236 COC(=O)c1ccccc1NC(=O)Nc2ncn(Cc3cccc(c3)C(F)(F)F)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F21 compound treatment 1518457.0 2700.0 0.01 1600922.0 187000.0 0.37 0.2675 0.7167 3629339 CBKinase1_019237 COC(=O)c1c(NC(=S)NCCn2cc(Br)cn2)sc3CCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F22 compound treatment 1552718.0 37000.0 0.07 1684182.0 270000.0 0.54 0.4306 0.7915 3629340 CBKinase1_019238 CCCC(=O)n1nc(nc1NCc2ccco2)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F23 compound treatment 1424641.0 -91100.0 -0.17 1033894.0 -380000.0 -0.76 -0.6584 -0.8451 3629341 CBKinase1_019239 COC(=O)c1c(NC(=S)Nc2cc(OC)c(Cl)cc2OC)sc3CCCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 F24 compound treatment 1470575.0 -45200.0 -0.08 440723.0 -973000.0 -1.95 -1.4358 -0.7372 3629342 CBKinase1_019240 CSc1ccccc1NC(=O)Cn2c(nc3ccccc23)c4cscn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G01 compound treatment 1322962.0 -193000.0 -0.36 1631765.0 218000.0 0.43 0.0515 0.0911 3629343 CBKinase1_019241 Cn1c2nnc(SCc3nc4ccc(cc4[nH]3)[N+](=O)[O-])n2c5ccccc15 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G02 compound treatment 1814739.0 299000.0 0.56 1619517.0 205000.0 0.41 0.6871 0.9881 3629344 CBKinase1_019242 O=C(CCC(=O)c1ccc(Oc2ccccc2)cc1)Nc3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G03 mock treatment 1902134.0 386000.0 0.73 1613392.0 199000.0 0.4 0.7944 0.9601 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G04 mock treatment 1849637.0 334000.0 0.63 1617094.0 203000.0 0.41 0.73 0.9778 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G05 compound treatment 2058682.0 543000.0 1.02 1913413.0 499000.0 1.0 1.4262 0.9999 1503771 CBKinase1_019243 Fc1cccc(F)c1NC(=O)CN2C(=O)c3ccccc3S2(=O)=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G06 compound treatment 2031988.0 516000.0 0.97 1693011.0 279000.0 0.56 1.0793 0.9655 3629345 CBKinase1_019244 COc1c(Cl)cc(cc1Cl)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3cc(C)nc(C)n3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G07 compound treatment 2038312.0 523000.0 0.98 1964231.0 550000.0 1.1 1.471 0.9984 3629346 CBKinase1_019245 COC(=O)c1cccc(NC(=O)CN(c2ccc(C)c(Cl)c2)S(=O)(=O)C)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G08 compound treatment 1967044.0 451000.0 0.85 1736820.0 323000.0 0.64 1.055 0.9909 3629347 CBKinase1_019246 CCOc1ccc(cc1)C(=O)c2oc3ccccc3c2NC(=O)c4ccccc4[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G09 compound treatment 2228481.0 713000.0 1.34 1811342.0 397000.0 0.79 1.5074 0.9689 3629348 CBKinase1_019247 Cn1c2nnc(SCC(=O)N3CCN(CC3)c4ccccc4)n2c5ccccc15 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G10 compound treatment 2107146.0 591000.0 1.11 1678546.0 264000.0 0.53 1.1587 0.9423 3629349 CBKinase1_019248 Cc1nnc(SCC(=O)Nc2cc(C)ccc2F)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G11 compound treatment 1539259.0 23500.0 0.04 1899839.0 486000.0 0.97 0.7175 0.7385 3629350 CBKinase1_019249 Cc1ccccc1NC(=O)CSc2nc(C)c3CCCCc3n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G12 compound treatment 1796278.0 281000.0 0.53 1604164.0 190000.0 0.38 0.6409 0.9871 3629351 CBKinase1_019250 CN(c1cccc(NC(=O)c2ccccc2N(C)S(=O)(=O)C)c1)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G13 compound treatment 2226691.0 711000.0 1.33 1924380.0 510000.0 1.02 1.6648 0.9912 2068420 CBKinase1_019251 OC(=O)C(CC(=O)Nc1ccc(Cl)cc1Cl)N2CCOCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G14 compound treatment 2225772.0 710000.0 1.33 1807022.0 393000.0 0.79 1.4977 0.9681 3629352 CBKinase1_019252 CS(=O)(=O)N(CC(=O)Nc1ccccc1C(=O)N2CCOCC2)c3ccc(I)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G15 compound treatment 1899104.0 383000.0 0.72 1926239.0 512000.0 1.02 1.2325 0.9852 3629353 CBKinase1_019253 COc1ccc(CN2C(=O)C(O)(CC(=O)c3ccc(C)o3)c4ccccc24)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G16 compound treatment 2218222.0 702000.0 1.32 1628820.0 215000.0 0.43 1.2358 0.8911 3629354 CBKinase1_019254 COc1ccc(C)cc1NC(=O)C(C)NS(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G17 compound treatment 1852810.0 337000.0 0.63 1853420.0 439000.0 0.88 1.0682 0.9871 3629355 CBKinase1_019255 Cc1nn(CCCNC(=S)Nc2cccc(c2)[N+](=O)[O-])c(C)c1Br 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G18 compound treatment 1899369.0 384000.0 0.72 1779068.0 365000.0 0.73 1.0249 1.0 3629356 CBKinase1_019256 Cc1cnn(CCCNC(=O)NC2(CC3CC4CC(C3)C2)C4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G19 mock treatment 1897575.0 382000.0 0.72 1430556.0 16400.0 0.03 0.53 0.7386 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G20 mock treatment 1626110.0 110000.0 0.21 1621018.0 207000.0 0.41 0.4388 0.949 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G21 compound treatment 1691860.0 176000.0 0.33 1748286.0 334000.0 0.67 0.7059 0.9474 3629357 CBKinase1_019257 COC(=O)c1ccc(NC(=O)CSc2nc(C)c(C)c(O)n2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G22 compound treatment 1518933.0 3180.0 0.01 1651329.0 237000.0 0.47 0.3393 0.716 3629358 CBKinase1_019258 CCOC(=O)c1cnc2c(C)c(C)ccc2c1NCc3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G23 compound treatment 1500909.0 -14800.0 -0.03 1568046.0 154000.0 0.31 0.1977 0.6404 3629359 CBKinase1_019259 COc1ccc(cc1Cl)N(CC(=O)Nc2ccc(F)c(F)c2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 G24 compound treatment 1335688.0 -180000.0 -0.34 1301814.0 -112000.0 -0.22 -0.3979 -0.9803 3629360 CBKinase1_019260 COc1ccc(NC(=S)NCc2cc(C)n(C)n2)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H01 compound treatment 1313495.0 -202000.0 -0.38 1676435.0 262000.0 0.52 0.1021 0.1578 3629361 CBKinase1_019261 COc1cc2c(cc1NC(=O)COc3ccc(cc3)[N+](=O)[O-])oc4ccccc42 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H02 compound treatment 1377228.0 -139000.0 -0.26 1775935.0 362000.0 0.72 0.3273 0.426 1272003 CBKinase1_019262 Nc1cc(N)nc(SCC(=O)N(c2ccccc2)c3ccccc3)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H03 mock treatment 1225359.0 -290000.0 -0.55 1743409.0 329000.0 0.66 0.0798 0.0933 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H04 mock treatment 1599691.0 83900.0 0.16 1832901.0 419000.0 0.84 0.7032 0.8257 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H05 compound treatment 1565242.0 49500.0 0.09 1821482.0 407000.0 0.81 0.6413 0.7827 3629362 CBKinase1_019263 OC(=O)c1ccccc1NC(=O)c2cccc(c2)S(=O)(=O)Nc3cccc(Br)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H06 compound treatment 362936.0 -1150000.0 -2.16 396514.0 -1020000.0 -2.03 -2.9686 -0.9995 3629363 CBKinase1_019264 Clc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=S)NCc3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H07 compound treatment 1553369.0 37600.0 0.07 1772425.0 358000.0 0.72 0.5562 0.7731 3629364 CBKinase1_019265 COc1ccc(CC(=O)Nc2cc(C)ccc2O)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H08 compound treatment 1626508.0 111000.0 0.21 1787321.0 373000.0 0.75 0.6743 0.871 3629365 CBKinase1_019266 CSc1ccccc1NC(=O)CN(c2cccc(Cl)c2Cl)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H09 compound treatment 1755547.0 240000.0 0.45 1826361.0 412000.0 0.82 0.9008 0.9596 3629366 CBKinase1_019267 OC(=O)c1ccccc1NS(=O)(=O)c2cccc(c2)C(=O)N3CCCc4ccccc34 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H10 compound treatment 1652138.0 136000.0 0.26 1866873.0 453000.0 0.9 0.8208 0.8729 3629367 CBKinase1_019268 COc1cc(ccc1NC(=O)NCc2ccco2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H11 compound treatment 1975305.0 460000.0 0.86 1949438.0 535000.0 1.07 1.3665 0.9943 3629368 CBKinase1_019269 CC(Oc1ccc(Br)cc1)C(=O)Nc2ccccc2[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H12 compound treatment 1764383.0 249000.0 0.47 2017006.0 603000.0 1.2 1.182 0.9148 3629369 CBKinase1_019270 COc1ccc(NC(=S)NCc2cccnc2)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H13 compound treatment 1807629.0 292000.0 0.55 2120570.0 706000.0 1.41 1.3858 0.915 3629370 CBKinase1_019271 CCOC(=O)c1c(NC(=O)CC2NCCNC2=O)sc3CCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H14 compound treatment 1844716.0 329000.0 0.62 1901929.0 488000.0 0.97 1.126 0.9757 3629371 CBKinase1_019272 CCc1nnc(SCC(=O)Nc2ccc(cc2)C(=O)OC)[nH]1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H15 compound treatment 1649696.0 134000.0 0.25 1805016.0 391000.0 0.78 0.7301 0.8898 3629372 CBKinase1_019273 COc1ccc(CN2C(=O)C(O)(CC(=O)c3ccc(Cl)s3)c4ccccc24)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H16 compound treatment 1758007.0 242000.0 0.45 1625803.0 212000.0 0.42 0.6206 0.9993 3629373 CBKinase1_019274 O=C(CSc1nnc(o1)c2cccnc2)c3ccc4ccccc4c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H17 compound treatment 1771196.0 255000.0 0.48 1839968.0 426000.0 0.85 0.9408 0.9632 3629374 CBKinase1_019275 CN(C)c1ccc(NC(=O)CC2NCCNC2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H18 compound treatment 1821965.0 306000.0 0.57 1950021.0 536000.0 1.07 1.1637 0.9575 3629375 CBKinase1_019276 COC(=O)c1cc(sc1NC(=S)NCc2ccccn2)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H19 mock treatment 1095837.0 -420000.0 -0.79 1652969.0 239000.0 0.48 -0.22 -0.2387 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H20 mock treatment 1380146.0 -136000.0 -0.25 1942755.0 529000.0 1.06 0.567 0.5218 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H21 compound treatment 1490970.0 -24800.0 -0.05 1731210.0 317000.0 0.63 0.4151 0.6534 3629376 CBKinase1_019277 CS(=O)(=O)N(CC(=O)Nc1ccc(F)c(F)c1)c2ccccc2F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H22 compound treatment 1453181.0 -62600.0 -0.12 1864819.0 451000.0 0.9 0.5538 0.6097 3629377 CBKinase1_019278 CCOC(=O)c1c(NC(=O)CSc2nc(C)c3CCCCc3n2)sc4CCCCc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H23 compound treatment 1623048.0 107000.0 0.2 1812795.0 399000.0 0.8 0.7058 0.8589 3629378 CBKinase1_019279 O=C(c1ccco1)n2nc(nc2NCc3ccco3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 H24 compound treatment 1627124.0 111000.0 0.21 1434253.0 20000.0 0.04 0.1762 0.8276 3629379 CBKinase1_019280 COC(=O)c1sccc1NC(=S)Nc2sc3CCCc3c2C(=O)OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I01 compound treatment 1738859.0 223000.0 0.42 1545467.0 131000.0 0.26 0.4817 0.9746 3629380 CBKinase1_019281 Cc1ccc(NS(=O)(=O)c2ccccc2)cc1CN3C(=O)c4ccccc4C3=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I02 compound treatment 1564294.0 48500.0 0.09 1369728.0 -44500.0 -0.09 0.0016 0.0124 3629381 CBKinase1_019282 CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)COc2ccc3ccccc3c2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I03 compound treatment 1854090.0 338000.0 0.64 1546544.0 132000.0 0.26 0.6362 0.9246 3629382 CBKinase1_019283 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)Nc3cccc(Cl)c3C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I04 compound treatment 1890936.0 375000.0 0.7 1486486.0 72300.0 0.14 0.6002 0.8348 3629383 CBKinase1_019284 COc1ccc(OC)c(NC(=O)NCc2cnn(C)c2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I05 mock treatment 1979055.0 463000.0 0.87 1521404.0 107000.0 0.21 0.7665 0.8557 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I06 mock treatment 1781942.0 266000.0 0.5 1899976.0 486000.0 0.97 1.0399 0.9523 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I07 compound treatment 1501798.0 -14000.0 -0.03 1577795.0 164000.0 0.33 0.2127 0.6484 3629384 CBKinase1_019285 Cc1ccc(cc1)n2c(SCC(=O)NC3CCCCC3)nnc2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I08 compound treatment 1871370.0 356000.0 0.67 1499975.0 85800.0 0.17 0.5933 0.8607 1658096 CBKinase1_019286 Cc1cc(C)cc(NC(=O)COc2ccc(cc2)N3CC(CC3=O)C(=O)N)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I09 compound treatment 1675307.0 160000.0 0.3 1420755.0 6550.0 0.01 0.2211 0.7373 3629385 CBKinase1_019287 Cc1cccc(C)c1N(CC(=O)Nc2cc(Cl)ccc2Oc3ccccc3)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I10 compound treatment 1872552.0 357000.0 0.67 1678707.0 265000.0 0.53 0.8475 0.9931 3629386 CBKinase1_019288 COC(=O)c1c(NC(=S)Nc2cnccn2)sc3CC(C)CCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I11 compound treatment 1834937.0 319000.0 0.6 1440606.0 26400.0 0.05 0.461 0.7664 3629387 CBKinase1_019289 COc1cccc(NC(=O)CC2NCCNC2=O)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I12 compound treatment 1597207.0 81500.0 0.15 1527248.0 113000.0 0.23 0.2679 0.9819 3629388 CBKinase1_019290 COc1ccc(C)cc1NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I13 compound treatment 1606249.0 90500.0 0.17 1638757.0 225000.0 0.45 0.4375 0.9116 3629389 CBKinase1_019291 Nc1cc(=O)nc(SCC(=O)N(c2ccccc2)c3ccccc3)n1c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I14 compound treatment 1836969.0 321000.0 0.6 1685176.0 271000.0 0.54 0.8094 0.9986 3629390 CBKinase1_019292 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)Nc3ccc(Nc4ccccc4)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I15 compound treatment 1632618.0 117000.0 0.22 1442719.0 28500.0 0.06 0.1954 0.8622 3629391 CBKinase1_019293 COc1ccc(OC)c(c1)C(C)NC(=O)Nc2cccc(c2)C(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I16 compound treatment 1812998.0 297000.0 0.56 1639640.0 225000.0 0.45 0.7132 0.9944 3629392 CBKinase1_019294 CCOC(=O)c1cnc2c(C)c(C)ccc2c1NCc3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I17 compound treatment 1692280.0 177000.0 0.33 1480054.0 65800.0 0.13 0.3274 0.9182 3629393 CBKinase1_019295 COc1ccc(cc1Cl)N(CC(=O)Nc2cccc(Cl)c2Cl)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I18 compound treatment 1671326.0 156000.0 0.29 1573956.0 160000.0 0.32 0.4323 0.999 3629394 CBKinase1_019296 Clc1ccc(NC(=O)CSc2nnc([nH]2)c3ccco3)c(Cl)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I19 compound treatment 1227557.0 -288000.0 -0.54 1593360.0 179000.0 0.36 -0.1294 -0.1994 3629395 CBKinase1_019297 COc1ccc(NC(=O)NCc2ccco2)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I20 compound treatment 1560403.0 44700.0 0.08 1597140.0 183000.0 0.37 0.3178 0.8472 3629396 CBKinase1_019298 COc1ccc(cc1S(=O)(=O)Nc2cccc(c2)C(=O)O)C(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I21 mock treatment 1630765.0 115000.0 0.22 1261225.0 -153000.0 -0.31 -0.0635 -0.1697 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I22 mock treatment 1459121.0 -56600.0 -0.11 1625701.0 211000.0 0.42 0.2237 0.5133 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I23 compound treatment 1428766.0 -87000.0 -0.16 1654576.0 240000.0 0.48 0.2242 0.4419 3629397 CBKinase1_019299 CCNS(=O)(=O)c1ccc(NC(=S)Nc2sc(C)c(C)c2C(=O)OC)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 I24 compound treatment 1534378.0 18600.0 0.03 1346413.0 -67800.0 -0.14 -0.0711 -0.508 3629398 CBKinase1_019300 FC(F)(F)c1cccc(NC(=O)c2ccc(OCC(=O)Nc3ccccc3)cc2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J01 compound treatment 1166996.0 -349000.0 -0.65 1253882.0 -160000.0 -0.32 -0.6896 -0.946 3629399 CBKinase1_019301 COC(=O)c1cccc(COC(=O)c2cc(O)nc3ccccc23)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J02 compound treatment 1150048.0 -366000.0 -0.69 1181077.0 -233000.0 -0.47 -0.8149 -0.9822 3629400 CBKinase1_019302 CS(=O)(=O)N(CC(=O)Nc1ccc(F)c(F)c1)c2ccc(Br)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J03 compound treatment 1108813.0 -407000.0 -0.76 1080501.0 -334000.0 -0.67 -1.0118 -0.9977 3629401 CBKinase1_019303 Cc1cccc(c1)C(=O)Nc2cc(C)ccc2NC(=O)COc3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J04 compound treatment 1375447.0 -140000.0 -0.26 1402524.0 -11700.0 -0.02 -0.2028 -0.7668 3629402 CBKinase1_019304 Cc1sc2ncn(CC(=O)Nc3ccc(Cl)cc3C)c(=O)c2c1c4ccc(F)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J05 mock treatment 1400878.0 -115000.0 -0.22 1449944.0 35700.0 0.07 -0.102 -0.4489 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J06 mock treatment 1640294.0 125000.0 0.23 1391078.0 -23100.0 -0.05 0.1326 0.5565 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J07 compound treatment 1584638.0 68900.0 0.13 1575361.0 161000.0 0.32 0.3192 0.9197 3629403 CBKinase1_019305 CC1CCN(CC1)S(=O)(=O)c2cccc(c2)C(=O)NC(C)(C)CO 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J08 compound treatment 1384274.0 -131000.0 -0.25 1613379.0 199000.0 0.4 0.107 0.2283 3629404 CBKinase1_019306 COC(=O)c1cc(NC(=O)CN(c2ccccc2F)S(=O)(=O)C)ccc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J09 compound treatment 1406785.0 -109000.0 -0.2 1398889.0 -15300.0 -0.03 -0.1663 -0.804 3629405 CBKinase1_019307 O=C(Nc1ccccc1)c2ccc(NCC3CCCO3)c(c2)S(=O)(=O)N4CCOCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J10 compound treatment 1250599.0 -265000.0 -0.5 1373342.0 -40900.0 -0.08 -0.4097 -0.8123 3629406 CBKinase1_019308 CSc1ccccc1NC(=O)C(C)NS(=O)(=O)c2ccc(C)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J11 compound treatment 1631823.0 116000.0 0.22 1532143.0 118000.0 0.24 0.3208 0.9992 3629407 CBKinase1_019309 CN(CC(=O)Nc1cc(Cl)ccc1O)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J12 compound treatment 1615239.0 99500.0 0.19 1557465.0 143000.0 0.29 0.3345 0.9786 3629408 CBKinase1_019310 [O-][N+](=O)c1cccc(c1)C2N(CCN3CCOCC3)C(=O)c4oc5ccccc5c(=O)c24 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J13 compound treatment 1569931.0 54200.0 0.1 1228903.0 -185000.0 -0.37 -0.19 -0.4946 3629409 CBKinase1_019311 Cc1ccc(NC(=O)CC(N)C(=O)O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J14 compound treatment 3950215.0 2430000.0 4.57 1227991.0 -186000.0 -0.37 2.9685 0.6474 3629410 CBKinase1_019312 COc1cccc(CN2CCN(CC2)C(=S)NCc3ccco3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J15 compound treatment 1530434.0 14700.0 0.03 1423443.0 9240.0 0.02 0.0325 0.981 3629411 CBKinase1_019313 CCOC(=O)c1c(NC(=S)Nc2cc(OC)c(Cl)cc2OC)sc(C)c1c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J16 compound treatment 1228514.0 -287000.0 -0.54 1161810.0 -252000.0 -0.5 -0.738 -0.9994 3629412 CBKinase1_019314 Cc1cc(C)c(c(C)c1)S(=O)(=O)N2CCN(CC(O)COc3ccc4ccccc4c3)CC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J17 compound treatment 1476683.0 -39100.0 -0.07 1644712.0 231000.0 0.46 0.2739 0.5871 3629413 CBKinase1_019315 COc1ccc2cc(Br)ccc2c1CC(=O)Nc3ccccc3OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J18 compound treatment 1511383.0 -4370.0 -0.01 1487786.0 73600.0 0.15 0.0982 0.6666 3629414 CBKinase1_019316 Cc1cccnc1NC(=S)Nc2ccc(cc2)S(=O)(=O)N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J19 compound treatment 1255296.0 -260000.0 -0.49 1400295.0 -13900.0 -0.03 -0.3654 -0.7461 3629415 CBKinase1_019317 CCOC(=O)c1c(NC(=S)NC(C)C2CCCO2)sc3CCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J20 compound treatment 1385677.0 -130000.0 -0.24 1285288.0 -129000.0 -0.26 -0.3549 -0.9996 3629416 CBKinase1_019318 COc1ccc(C)c(Cn2c(nc3ccccc23)c4nonc4N)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J21 mock treatment 1431749.0 -84000.0 -0.16 1402068.0 -12100.0 -0.02 -0.1287 -0.8064 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J22 mock treatment 1569044.0 53300.0 0.1 1222986.0 -191000.0 -0.38 -0.1995 -0.505 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J23 compound treatment 1314502.0 -201000.0 -0.38 1359947.0 -54300.0 -0.11 -0.3438 -0.8747 1985090 CBKinase1_019319 Fc1ccc(cc1)C(=O)CCC(=O)Nc2cccnc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 J24 compound treatment 1564001.0 48200.0 0.09 961036.0 -453000.0 -0.91 -0.5764 -0.6332 3629417 CBKinase1_019320 O=C(CSc1nnc([nH]1)c2ccco2)N3c4ccccc4Sc5ccccc35 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K01 compound treatment 1502509.0 -13200.0 -0.02 1401642.0 -12600.0 -0.03 -0.0353 -1.0 3629418 CBKinase1_019321 COC(=O)c1c(NC(=S)Nc2ccn(n2)C3(CC4CC5CC(C4)C3)C5)sc6CCCc16 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K02 compound treatment 1511175.0 -4580.0 -0.01 1124745.0 -289000.0 -0.58 -0.4152 -0.7175 1209698 CBKinase1_019322 CSc1ccccc1NC(=O)CN2C(=O)c3ccccc3S2(=O)=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K03 compound treatment 1155146.0 -361000.0 -0.68 1172920.0 -241000.0 -0.48 -0.8197 -0.9862 3629419 CBKinase1_019323 COC(=O)c1ccccc1NC(=O)NCc2ccccn2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K04 compound treatment 1299574.0 -216000.0 -0.41 1199331.0 -215000.0 -0.43 -0.5907 -0.9996 3629420 CBKinase1_019324 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Oc2ccccc2)c3ccccc3F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K05 compound treatment 1478537.0 -37200.0 -0.07 1513619.0 99400.0 0.2 0.0911 0.4325 3629421 CBKinase1_019325 CCN1CCN(CC1)C(=O)C(C)N(c2ccc(OC)cc2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K06 compound treatment 1479962.0 -35800.0 -0.07 1208791.0 -205000.0 -0.41 -0.3378 -0.812 3629422 CBKinase1_019326 COc1ccc(OCC(=O)Nc2c(oc3ccccc23)C(=O)c4ccc(C)c(F)c4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K07 mock treatment 1672331.0 157000.0 0.29 1445860.0 31700.0 0.06 0.2526 0.8401 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K08 mock treatment 1604681.0 88900.0 0.17 1464346.0 50100.0 0.1 0.1889 0.9702 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K09 compound treatment 1742643.0 227000.0 0.43 1494835.0 80600.0 0.16 0.4151 0.9116 3629423 CBKinase1_019327 COc1ccccc1N(CC(=O)Nc2ccc(F)c(F)c2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K10 compound treatment 1556651.0 40900.0 0.08 1189174.0 -225000.0 -0.45 -0.2637 -0.578 3629424 CBKinase1_019328 COc1ccccc1NC(=O)Cn2nnc(n2)c3cc(OC)c(OC)c(OC)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K11 compound treatment 1662206.0 146000.0 0.27 1640418.0 226000.0 0.45 0.5141 0.9716 3629425 CBKinase1_019329 Cc1cc(C)cc(c1)N(CC(=O)Nc2c(F)cccc2F)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K12 compound treatment 1400061.0 -116000.0 -0.22 1525779.0 112000.0 0.22 0.0041 0.0132 3629426 CBKinase1_019330 COc1ccc(cc1OC)C(=O)NC(CC(C)C)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K13 compound treatment 1584171.0 68400.0 0.13 1673448.0 259000.0 0.52 0.4572 0.8565 3629427 CBKinase1_019331 COc1cc(ccc1NC(=O)Nc2ncccc2C)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K14 compound treatment 1629533.0 114000.0 0.21 1674944.0 261000.0 0.52 0.5195 0.9225 3629428 CBKinase1_019332 COc1ccc(Cl)cc1NC(=S)Nc2cccc(c2)S(=O)(=O)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K15 mock treatment 1587037.0 71300.0 0.13 1172963.0 -241000.0 -0.48 -0.2463 -0.4922 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K16 mock treatment 1345839.0 -170000.0 -0.32 1450843.0 36600.0 0.07 -0.1738 -0.531 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K17 compound treatment 1751517.0 236000.0 0.44 1507439.0 93200.0 0.19 0.4447 0.9261 2068184 CBKinase1_019333 Cc1ccc(C)c(NC(=O)CC(NC2CCCCC2)C(=O)O)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K18 compound treatment 1593029.0 77300.0 0.15 1389884.0 -24300.0 -0.05 0.0682 0.4458 3629429 CBKinase1_019334 COc1ccc(CCNC(=O)c2ccnc(c2)C(C)(C)C)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K19 compound treatment 1329325.0 -186000.0 -0.35 1586631.0 172000.0 0.34 -0.0038 -0.0077 3629430 CBKinase1_019335 COC(=O)c1cc(Cc2ccccc2)sc1NC(=S)Nc3ccn(C)n3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K20 compound treatment 1265747.0 -250000.0 -0.47 1373764.0 -40400.0 -0.08 -0.389 -0.8169 3629431 CBKinase1_019336 COc1ccc(cc1c2nnc3c4ccccc4c(C)nn23)S(=O)(=O)N5CCN(CCO)CC5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K21 compound treatment 1474485.0 -41300.0 -0.08 1366568.0 -47600.0 -0.1 -0.1221 -0.9948 3629432 CBKinase1_019337 CCN1CCN(CC1)C(=O)CN(c2ccc(OC)c(Cl)c2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K22 compound treatment 1560892.0 45100.0 0.08 1484621.0 70400.0 0.14 0.1594 0.9705 3629433 CBKinase1_019338 COc1ccccc1N(CC(=O)Nc2ccc(cc2)C(F)(F)F)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K23 mock treatment 1177598.0 -338000.0 -0.63 1231345.0 -183000.0 -0.37 -0.7073 -0.9656 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 K24 mock treatment 1630294.0 115000.0 0.22 1349096.0 -65100.0 -0.13 0.06 0.2388 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L01 compound treatment 1299345.0 -216000.0 -0.41 994945.0 -419000.0 -0.84 -0.8798 -0.9448 3629434 CBKinase1_019339 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc3ccc4OCCOc4c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L02 compound treatment 1027406.0 -488000.0 -0.92 1199871.0 -214000.0 -0.43 -0.9512 -0.94 3629435 CBKinase1_019340 COC(=O)c1ccc(Cl)c(NC(=O)COc2ccc(OC)cc2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L03 compound treatment 1113267.0 -402000.0 -0.76 1169257.0 -245000.0 -0.49 -0.8805 -0.9779 3629436 CBKinase1_019341 CC(Oc1ccc(Br)cc1)C(=O)Nc2nnc[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L04 compound treatment 1139020.0 -377000.0 -0.71 970353.0 -444000.0 -0.89 -1.1274 -0.9937 3629437 CBKinase1_019342 CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2ccc(C)c(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L05 compound treatment 1271698.0 -244000.0 -0.46 1065013.0 -349000.0 -0.7 -0.8175 -0.9792 3629438 CBKinase1_019343 Cc1ccc(NC(=O)COc2ccccc2)c(NC(=O)c3ccccc3I)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L06 compound treatment 1287506.0 -228000.0 -0.43 1015728.0 -398000.0 -0.8 -0.8662 -0.9577 3629439 CBKinase1_019344 COc1ccc(NC(=O)Cn2c(nc3sc4CCCCc4c3c2=O)c5ccccc5)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L07 mock treatment 1370421.0 -145000.0 -0.27 1077562.0 -337000.0 -0.67 -0.6687 -0.921 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L08 mock treatment 1268718.0 -247000.0 -0.46 1317957.0 -96200.0 -0.19 -0.464 -0.9241 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L09 compound treatment 1265815.0 -250000.0 -0.47 1047861.0 -366000.0 -0.73 -0.8495 -0.9769 1365377 CBKinase1_019345 COC(=O)c1cccc(NC(=O)COc2cc(C)ccc2C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L10 compound treatment 1320325.0 -195000.0 -0.37 1142473.0 -272000.0 -0.54 -0.6435 -0.9818 3629440 CBKinase1_019346 CS(=O)(=O)N(CC(=O)Nc1ccccc1Sc2ccccc2)c3ccc(F)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L11 compound treatment 1280273.0 -235000.0 -0.44 992493.0 -422000.0 -0.84 -0.9086 -0.9546 3629441 CBKinase1_019347 Cc1cccc(OCC(=O)Nc2cccc(C(=O)O)c2C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L12 compound treatment 1082912.0 -433000.0 -0.81 1333553.0 -80700.0 -0.16 -0.6886 -0.8312 3629442 CBKinase1_019348 CCOC(=O)c1cnc2c(C)c(C)ccc2c1NCCCN3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L13 compound treatment 1195045.0 -321000.0 -0.6 1412400.0 -1810.0 0.0 -0.4283 -0.7113 1986239 CBKinase1_019349 CCn1c2nnc(SCc3nc4ccccc4[nH]3)n2c5ccccc15 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L14 compound treatment 1287003.0 -229000.0 -0.43 1395831.0 -18400.0 -0.04 -0.3296 -0.7648 3629443 CBKinase1_019350 CC(C)N(Cc1nc(no1)c2ccc(Cl)cc2)S(=O)(=O)c3cccc(c3)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L15 mock treatment 1445486.0 -70300.0 -0.13 1442438.0 28200.0 0.06 -0.0534 -0.372 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L16 mock treatment 1257326.0 -258000.0 -0.49 1560863.0 147000.0 0.29 -0.1358 -0.2396 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L17 compound treatment 1265890.0 -250000.0 -0.47 743049.0 -671000.0 -1.34 -1.2802 -0.9009 3629444 CBKinase1_019351 CC(=O)c1cccc(NC(=S)NCc2ccco2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L18 compound treatment 978891.0 -537000.0 -1.01 1145792.0 -268000.0 -0.54 -1.092 -0.9564 3629445 CBKinase1_019352 CCN1CCN(CC1)C(=O)CN(c2cccc(c2)[N+](=O)[O-])S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L19 compound treatment 1219762.0 -296000.0 -0.56 1027580.0 -387000.0 -0.77 -0.9393 -0.9869 3629446 CBKinase1_019353 Cc1ccccc1c2nnc(SCC(=O)Nc3cccc(c3)[N+](=O)[O-])o2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L20 compound treatment 1040080.0 -476000.0 -0.89 1477142.0 62900.0 0.13 -0.5425 -0.6016 3629447 CBKinase1_019354 COC(=O)c1sc(NC(=S)Nc2cc(OC)c(Cl)cc2OC)c(C(=O)OC)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L21 compound treatment 721586.0 -794000.0 -1.49 472639.0 -942000.0 -1.88 -2.3849 -0.9933 3629448 CBKinase1_019355 Oc1c(Sc2nc[nH]n2)cc(NS(=O)(=O)c3cccs3)c4ccccc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L22 compound treatment 1415377.0 -100000.0 -0.19 1048143.0 -366000.0 -0.73 -0.6506 -0.8611 3629449 CBKinase1_019356 FC(F)(F)c1cccc(NC(=O)Nc2cccc(c2)S(=O)(=O)N3CCOCC3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L23 mock treatment 1303480.0 -212000.0 -0.4 1110569.0 -304000.0 -0.61 -0.7109 -0.9792 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 L24 mock treatment 1401607.0 -114000.0 -0.21 1337951.0 -76300.0 -0.15 -0.2593 -0.9861 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M01 compound treatment 1429268.0 -86500.0 -0.16 1146958.0 -267000.0 -0.53 -0.4925 -0.8822 3629450 CBKinase1_019357 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)Nc3ccc4OCCOc4c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M02 compound treatment 1544897.0 29100.0 0.05 1291731.0 -122000.0 -0.24 -0.1344 -0.5358 3629451 CBKinase1_019358 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)C)S(=O)(=O)c3cccc4cccnc34 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M03 compound treatment 1528506.0 12800.0 0.02 1194104.0 -220000.0 -0.44 -0.2941 -0.6676 3629452 CBKinase1_019359 COc1ccc(cc1NC(=S)NCc2ccco2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M04 compound treatment 1485590.0 -30200.0 -0.06 1258292.0 -156000.0 -0.31 -0.2604 -0.8221 3629453 CBKinase1_019360 COc1ccc(Cl)cc1NC(=O)CC2N(CCNC2=O)C(=S)Nc3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M05 compound treatment 1177995.0 -338000.0 -0.63 1259448.0 -155000.0 -0.31 -0.6671 -0.9455 3629454 CBKinase1_019361 OC1(CC(=O)c2cccc(c2)n3cccc3)C(=O)Nc4ccc(Br)cc41 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M06 compound treatment 1175451.0 -340000.0 -0.64 843459.0 -571000.0 -1.14 -1.2584 -0.9625 3629455 CBKinase1_019362 CCOC(=O)c1c(NC(=S)NC(C)c2ccncc2)sc3CCCCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M07 compound treatment 1719916.0 204000.0 0.38 1317001.0 -97200.0 -0.19 0.1336 0.311 3629456 CBKinase1_019363 Cc1ccccc1NC(=O)c2ccccc2NS(=O)(=O)c3cccc4cccnc34 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M08 compound treatment 1415877.0 -99900.0 -0.19 1157544.0 -257000.0 -0.51 -0.4953 -0.9069 3629457 CBKinase1_019364 Cc1cc(C)c(NC(=O)CN(C2CCCCC2)S(=O)(=O)c3ccc(Br)cc3)c(C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M09 mock treatment 1643352.0 128000.0 0.24 1193914.0 -220000.0 -0.44 -0.1419 -0.2832 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M10 mock treatment 1729872.0 214000.0 0.4 1400500.0 -13700.0 -0.03 0.2649 0.6574 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M11 compound treatment 1860635.0 345000.0 0.65 1322691.0 -91500.0 -0.18 0.3285 0.4882 3629458 CBKinase1_019365 Cc1ccc(s1)C(=O)CC2(O)C(=O)N(Cc3cccc4ccccc34)c5ccccc52 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M12 compound treatment 1700903.0 185000.0 0.35 1219143.0 -195000.0 -0.39 -0.0299 -0.0572 3629459 CBKinase1_019366 CCN1CCN(CC1)C(=O)C(C)N(c2ccccc2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M13 mock treatment 1732456.0 217000.0 0.41 1225805.0 -188000.0 -0.38 0.0214 0.0386 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M14 mock treatment 1446681.0 -69100.0 -0.13 1258412.0 -156000.0 -0.31 -0.3119 -0.9246 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M15 compound treatment 1766848.0 251000.0 0.47 1243365.0 -171000.0 -0.34 0.0919 0.1578 3629460 CBKinase1_019367 COc1ccc(cc1Cl)C(=O)c2oc3ccccc3c2NC(=O)COc4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M16 compound treatment 1587367.0 71600.0 0.13 1341441.0 -72800.0 -0.15 -0.0078 -0.0392 3629461 CBKinase1_019368 COc1ccc(cc1)N(C(C)C(=O)Nc2ccc(Cl)c(Cl)c2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M17 compound treatment 1362073.0 -154000.0 -0.29 1031245.0 -383000.0 -0.77 -0.7452 -0.9111 3629462 CBKinase1_019369 CCN1CCN(CC1)C(=O)CN(c2cc(Cl)ccc2OC)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M18 compound treatment 1712725.0 197000.0 0.37 1335468.0 -78700.0 -0.16 0.1502 0.3737 3629463 CBKinase1_019370 Cc1ccc(cc1NC(=O)CN2C(=O)c3cccc4cccc2c34)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M19 compound treatment 1737927.0 222000.0 0.42 1172236.0 -242000.0 -0.48 -0.047 -0.0737 3629464 CBKinase1_019371 Cc1c(CCC(=O)O)c(=O)oc2c(C)c(OCc3ccc(Br)cc3F)ccc12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M20 compound treatment 1678989.0 163000.0 0.31 1105996.0 -308000.0 -0.62 -0.2189 -0.3181 3629465 CBKinase1_019372 COC(=O)c1c(NC(=S)N(C)Cc2c(C)nn(C)c2C)sc3CCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M21 compound treatment 1559840.0 44100.0 0.08 1259915.0 -154000.0 -0.31 -0.1595 -0.4996 3629466 CBKinase1_019373 CS(=O)(=O)N(CC(=O)Nc1cccc(Cl)c1Cl)c2cccc(Cl)c2Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M22 compound treatment 580681.0 -935000.0 -1.76 478393.0 -936000.0 -1.87 -2.5639 -0.9995 3629467 CBKinase1_019374 COc1cc(C)c(Cl)cc1S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M23 compound treatment 1724381.0 209000.0 0.39 1238215.0 -176000.0 -0.35 0.0282 0.0536 3629468 CBKinase1_019375 Cc1c(CCC(=O)O)c(=O)oc2cc(OCc3ccc(Br)cc3)ccc12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 M24 compound treatment 1510662.0 -5090.0 -0.01 1048530.0 -366000.0 -0.73 -0.5236 -0.7163 3629469 CBKinase1_019376 CSc1ccccc1NC(=O)CN(c2cc(C)cc(C)c2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N01 compound treatment 1300951.0 -215000.0 -0.4 1153097.0 -261000.0 -0.52 -0.6542 -0.9919 3629470 CBKinase1_019377 Cc1cccc(C)c1OCC(=O)Nc2cccc(c2)c3nc4ccccc4s3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N02 compound treatment 1345736.0 -170000.0 -0.32 1198308.0 -216000.0 -0.43 -0.5308 -0.989 3629471 CBKinase1_019378 O=C(CN1C(=O)c2cccc3cccc1c23)Nc4ccccc4C(=O)N5CCOCC5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N03 compound treatment 1198140.0 -318000.0 -0.6 1134111.0 -280000.0 -0.56 -0.8175 -0.9995 3629472 CBKinase1_019379 COC(=O)c1cn(C(=O)CCCN2C(=O)c3ccccc3C2=O)c4ccccc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N04 compound treatment 1190465.0 -325000.0 -0.61 1366048.0 -48200.0 -0.1 -0.4999 -0.8086 3629473 CBKinase1_019380 Fc1cc(F)c(NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3)c(Br)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N05 compound treatment 1154396.0 -361000.0 -0.68 1214946.0 -199000.0 -0.4 -0.7613 -0.9678 3629474 CBKinase1_019381 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2ccccc2N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N06 compound treatment 1113999.0 -402000.0 -0.75 994331.0 -420000.0 -0.84 -1.1267 -0.9986 3629475 CBKinase1_019382 COc1cccc(NC(=O)CN(C)S(=O)(=O)c2ccc3ccccc3c2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N07 compound treatment 1338910.0 -177000.0 -0.33 1206928.0 -207000.0 -0.41 -0.5277 -0.994 3629476 CBKinase1_019383 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc3ccccc3c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N08 compound treatment 1102313.0 -413000.0 -0.78 1047530.0 -367000.0 -0.73 -1.067 -0.9996 3629477 CBKinase1_019384 Fc1ccc(cc1)C(CCNC(=O)c2cccs2)c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N09 mock treatment 1333990.0 -182000.0 -0.34 1369874.0 -44300.0 -0.09 -0.3039 -0.8621 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N10 mock treatment 1426262.0 -89500.0 -0.17 1202060.0 -212000.0 -0.42 -0.4186 -0.9179 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N11 compound treatment 1321178.0 -195000.0 -0.37 1159909.0 -254000.0 -0.51 -0.6177 -0.9869 3629478 CBKinase1_019385 Fc1ccc(NC(=O)CCCN2C(=O)c3ccccc3C2=O)c(F)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N12 compound treatment 1574429.0 58700.0 0.11 1306094.0 -108000.0 -0.22 -0.0749 -0.3088 3629479 CBKinase1_019386 COC(=O)c1cc(NC(=O)CN2C(=O)c3cccc4cccc2c34)ccc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N13 mock treatment 1462485.0 -53300.0 -0.1 1293783.0 -120000.0 -0.24 -0.2409 -0.9243 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N14 mock treatment 1417066.0 -98700.0 -0.19 1226527.0 -188000.0 -0.38 -0.3962 -0.9471 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N15 compound treatment 1454629.0 -61100.0 -0.11 1243416.0 -171000.0 -0.34 -0.3225 -0.8956 3629480 CBKinase1_019387 Cc1cc(F)ccc1S(=O)(=O)N(C(=O)c2ccncc2)c3ccc(OC(=O)c4ccncc4)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N16 compound treatment 1389593.0 -126000.0 -0.24 1384015.0 -30200.0 -0.06 -0.2101 -0.8598 3629481 CBKinase1_019388 COc1cccc(c1)N(CC(=O)Nc2ccc(Br)cc2F)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N17 compound treatment 1301390.0 -214000.0 -0.4 1333697.0 -80500.0 -0.16 -0.3983 -0.9191 3629482 CBKinase1_019389 CCc1c(C)sc(NC(=S)NCc2ccco2)c1C(=O)OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N18 compound treatment 1467774.0 -48000.0 -0.09 1305916.0 -108000.0 -0.22 -0.2167 -0.9245 3629483 CBKinase1_019390 CCn1ccc(CNC(=O)Nc2ccc(Cl)cc2Cl)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N19 compound treatment 1520921.0 5170.0 0.01 1026996.0 -387000.0 -0.77 -0.5404 -0.6982 3629484 CBKinase1_019391 Cc1ccc(C)c(c1)C(=O)CCC(=O)Nc2cccnc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N20 compound treatment 1549835.0 34100.0 0.06 1188393.0 -226000.0 -0.45 -0.2739 -0.6009 3629485 CBKinase1_019392 CCn1cc(CN(C)C(=S)Nc2cccc(c2)C(=O)C)c(C)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N21 compound treatment 1401751.0 -114000.0 -0.21 1229185.0 -185000.0 -0.37 -0.4128 -0.9662 3629486 CBKinase1_019393 CCOC(=O)c1sc(NC(=S)N2CCN(CC2)c3ncccn3)c(C(=O)OCC)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N22 compound treatment 1494605.0 -21100.0 -0.04 1341494.0 -72700.0 -0.15 -0.1308 -0.8685 3629487 CBKinase1_019394 COc1ccc(Cl)cc1N(CC(=O)Nc2ccc(Br)cc2F)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N23 compound treatment 1604994.0 89200.0 0.17 1232523.0 -182000.0 -0.36 -0.1383 -0.3458 3629488 CBKinase1_019395 CCc1ccccc1NC(=O)CC2NCCNC2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 N24 compound treatment 1712312.0 197000.0 0.37 1293701.0 -121000.0 -0.24 0.0906 0.2057 3629489 CBKinase1_019396 Cc1cc(=O)oc2cc(NC(=S)NCc3cccnc3)ccc12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O01 compound treatment 730463.0 -785000.0 -1.47 607944.0 -806000.0 -1.61 -2.1819 -0.999 3629490 CBKinase1_019397 Cc1ccc(c(C)c1)S(=O)(=O)Nc2cc(Sc3nc[nH]n3)c(O)c4ccccc24 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O02 compound treatment 1010021.0 -506000.0 -0.95 694185.0 -720000.0 -1.44 -1.6889 -0.9796 3629491 CBKinase1_019398 COc1ccc(Cl)cc1N(CC(=O)Nc2ccc(cc2)C(F)(F)F)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O03 compound treatment 877618.0 -638000.0 -1.2 702204.0 -712000.0 -1.42 -1.8534 -0.9963 3629492 CBKinase1_019399 CCOC(=O)c1ccc(NC(=O)CC2Sc3ncnn3C2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O04 compound treatment 842734.0 -673000.0 -1.26 927402.0 -487000.0 -0.97 -1.5814 -0.9917 3629493 CBKinase1_019400 Cc1ccc(cc1)C(=O)n2nc(nc2NCc3ccco3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O05 compound treatment 798313.0 -717000.0 -1.35 1027612.0 -387000.0 -0.77 -1.4988 -0.9652 3629494 CBKinase1_019401 COc1ccc(Cl)cc1NC(=O)CN2C(=O)COc3ccc(Cl)cc23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O06 compound treatment 973432.0 -542000.0 -1.02 949908.0 -464000.0 -0.93 -1.3761 -0.9989 3629495 CBKinase1_019402 CC(NS(=O)(=O)c1ccc(Br)cc1)C(=O)Nc2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O07 compound treatment 859075.0 -657000.0 -1.23 800646.0 -614000.0 -1.23 -1.7389 -1.0 3629496 CBKinase1_019403 CCCOc1ccc(cc1OC)C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccccc4OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O08 compound treatment 950159.0 -566000.0 -1.06 833516.0 -581000.0 -1.16 -1.5715 -0.999 3629497 CBKinase1_019404 Cc1c(Cl)cccc1NC(=O)COc2ccc(cc2)C(=O)Nc3cccc(c3)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O09 compound treatment 1189337.0 -326000.0 -0.61 818485.0 -596000.0 -1.19 -1.2752 -0.9523 3629498 CBKinase1_019405 CC(Sc1nc(C)cc(C)n1)C(=O)Nc2cccc(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O10 compound treatment 829865.0 -686000.0 -1.29 805910.0 -608000.0 -1.22 -1.7702 -0.9996 3629499 CBKinase1_019406 CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2cc(Cl)ccc2Oc3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O11 mock treatment 976102.0 -540000.0 -1.01 931241.0 -483000.0 -0.97 -1.3989 -0.9997 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O12 mock treatment 866120.0 -650000.0 -1.22 871262.0 -543000.0 -1.09 -1.6297 -0.9983 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O13 compound treatment 880542.0 -635000.0 -1.19 1059045.0 -355000.0 -0.71 -1.3452 -0.9693 3629500 CBKinase1_019407 COc1ccccc1NC(=O)CSc2nnnn2c3c(C)cccc3C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O14 compound treatment 1041990.0 -474000.0 -0.89 792106.0 -622000.0 -1.24 -1.5081 -0.9865 3629501 CBKinase1_019408 Clc1ccc(NC(=O)CSc2nnc(o2)c3ccncc3)c(Cl)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O15 compound treatment 1005655.0 -510000.0 -0.96 854298.0 -560000.0 -1.12 -1.4685 -0.997 3629502 CBKinase1_019409 CN(c1ccccc1C(=O)NCc2ccccn2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O16 compound treatment 974638.0 -541000.0 -1.02 755029.0 -659000.0 -1.32 -1.6499 -0.9917 3629503 CBKinase1_019410 Cc1c(NC(=O)CSc2nc(C)c(C)c(O)n2)c(=O)n(c3ccccc3)n1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O17 compound treatment 989067.0 -527000.0 -0.99 1049795.0 -364000.0 -0.73 -1.2142 -0.9887 3629504 CBKinase1_019411 CC1CCCCC1NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O18 compound treatment 966040.0 -550000.0 -1.03 990612.0 -424000.0 -0.85 -1.3284 -0.9952 3629505 CBKinase1_019412 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Oc2ccccc2)c3cccc(c3)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O19 compound treatment 1202732.0 -313000.0 -0.59 833369.0 -581000.0 -1.16 -1.2364 -0.9502 3629506 CBKinase1_019413 CC(NC(=S)NCc1ccco1)C2CCCO2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O20 compound treatment 1059674.0 -456000.0 -0.86 980706.0 -434000.0 -0.87 -1.2181 -1.0 3629507 CBKinase1_019414 COC(=O)c1sc2cc(NC(=S)NCCn3cc(Br)cn3)ccc2c1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O21 compound treatment 1050862.0 -465000.0 -0.87 1054750.0 -359000.0 -0.72 -1.1251 -0.9953 3629508 CBKinase1_019415 O=C(CCC(=O)c1ccc(cc1)c2ccccc2)Nc3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O22 compound treatment 991037.0 -525000.0 -0.99 844923.0 -569000.0 -1.14 -1.5011 -0.9974 3629509 CBKinase1_019416 CCc1nnc(SCC(=O)N(c2ccccc2)c3ccccc3)[nH]1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O23 compound treatment 907946.0 -608000.0 -1.14 1022773.0 -391000.0 -0.78 -1.3601 -0.9831 3629510 CBKinase1_019417 O=C(CN1C(=O)COc2ccccc12)Nc3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 O24 compound treatment 909784.0 -606000.0 -1.14 822576.0 -592000.0 -1.18 -1.6406 -0.9998 3629511 CBKinase1_019418 [O-][N+](=O)c1ncn(CC(=O)Nc2ccc(Cl)cc2C(F)(F)F)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P01 compound treatment 767006.0 -749000.0 -1.41 614203.0 -800000.0 -1.6 -2.1246 -0.9979 3629512 CBKinase1_019419 NC(=O)c1ccc(NC(=O)CCCN2C(=O)c3ccccc3C2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P02 compound treatment 779100.0 -737000.0 -1.38 689837.0 -724000.0 -1.45 -2.0016 -0.9997 3629513 CBKinase1_019420 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)Nc3cccc(Br)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P03 compound treatment 1446255.0 -69500.0 -0.13 789683.0 -625000.0 -1.25 -0.9749 -0.7768 3629514 CBKinase1_019421 COC(=O)c1cccc(COC(=O)c2ccc(NC(=O)c3ccco3)cc2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P04 compound treatment 720637.0 -795000.0 -1.49 776606.0 -638000.0 -1.27 -1.9566 -0.9969 3629515 CBKinase1_019422 COc1ccc(CC(=O)NCc2nnc(S)n2C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P05 compound treatment 722012.0 -794000.0 -1.49 688780.0 -725000.0 -1.45 -2.0789 -0.9999 3629516 CBKinase1_019423 CC(=O)Nc1ccccc1NC(=O)COc2cc(Cl)c(Cl)cc2Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P06 compound treatment 730958.0 -785000.0 -1.47 800117.0 -614000.0 -1.23 -1.9097 -0.9959 3629517 CBKinase1_019424 COc1ccc(Cl)cc1NC(=S)NCCCn2nc(C)c(Br)c2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P07 compound treatment 749803.0 -766000.0 -1.44 836917.0 -577000.0 -1.15 -1.8327 -0.994 1565142 CBKinase1_019425 CN(C)S(=O)(=O)c1cc(C(=O)NCC2CCCO2)c(Cl)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P08 compound treatment 863090.0 -653000.0 -1.23 1013312.0 -401000.0 -0.8 -1.433 -0.9788 3629518 CBKinase1_019426 CN(CC(=O)Nc1cc(ccc1Cl)C(F)(F)F)S(=O)(=O)c2ccc3ccccc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P09 compound treatment 776790.0 -739000.0 -1.39 796940.0 -617000.0 -1.23 -1.8533 -0.9983 3629519 CBKinase1_019427 COc1ccc(cc1NC(=O)C(C)Oc2ccc(Cl)cc2Cl)c3nc4ccccc4o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P10 compound treatment 778211.0 -738000.0 -1.38 1024966.0 -389000.0 -0.78 -1.5292 -0.9628 3629520 CBKinase1_019428 COC(=O)CCSc1ncnc2c1sc3nc(N4CCOCC4)c5CCCCc5c32 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P11 mock treatment 861778.0 -654000.0 -1.23 669487.0 -745000.0 -1.49 -1.9206 -0.9954 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P12 mock treatment 940730.0 -575000.0 -1.08 1121848.0 -292000.0 -0.58 -1.1765 -0.9585 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P13 compound treatment 934021.0 -582000.0 -1.09 1034320.0 -380000.0 -0.76 -1.3091 -0.9842 3629521 CBKinase1_019429 COC(=O)c1c(NC(=S)Nc2cc(OC)c(OC)cc2C(=O)OC)sc3CCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P14 compound treatment 795728.0 -720000.0 -1.35 1043161.0 -371000.0 -0.74 -1.4802 -0.9601 3629522 CBKinase1_019430 COc1cc(cc(OC)c1OC)c2nnn(CC(=O)O)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P15 compound treatment 1063128.0 -453000.0 -0.85 785153.0 -629000.0 -1.26 -1.4899 -0.9818 3629523 CBKinase1_019431 Cn1c(=O)n(C)c2ncn(CC(=O)NCc3ccccc3Cl)c2c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P16 compound treatment 713169.0 -803000.0 -1.51 1014743.0 -399000.0 -0.8 -1.63 -0.9559 1986351 CBKinase1_019432 Cc1ccc2nsnc2c1S(=O)(=O)N3CCN=C3Cc4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P17 compound treatment 868068.0 -648000.0 -1.22 1052248.0 -362000.0 -0.72 -1.3713 -0.9692 3629524 CBKinase1_019433 FC(F)(F)c1cccc(NC(=O)CC2NC3CCCCC3NC2=O)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P18 compound treatment 785385.0 -730000.0 -1.37 1056769.0 -357000.0 -0.71 -1.4747 -0.9538 3629525 CBKinase1_019434 O=C(C1CCCO1)N2CCN(CC2)C(=S)Nc3ccc(cc3)S(=O)(=O)Nc4ncccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P19 compound treatment 921824.0 -594000.0 -1.12 882675.0 -532000.0 -1.06 -1.5396 -0.9997 3629526 CBKinase1_019435 CCOc1ccc(cc1)C(=O)c2oc3ccccc3c2NC(=O)c4cc5ccccc5oc4=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P20 compound treatment 882201.0 -634000.0 -1.19 843985.0 -570000.0 -1.14 -1.6469 -0.9998 2068347 CBKinase1_019436 Cc1ccc(Cl)cc1NC(=O)CC(N2CCNCC2)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P21 compound treatment 1110885.0 -405000.0 -0.76 838306.0 -576000.0 -1.15 -1.3514 -0.9797 3629527 CBKinase1_019437 Cc1ccc2oc(nc2c1)c3cc(NC(=O)c4nc[nH]n4)ccc3O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P22 compound treatment 936657.0 -579000.0 -1.09 968505.0 -446000.0 -0.89 -1.3986 -0.9951 1515306 CBKinase1_019438 COC(=O)c1ccccc1NC(=O)NCc2ccc(OC)c(OC)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P23 compound treatment 843864.0 -672000.0 -1.26 674905.0 -739000.0 -1.48 -1.9368 -0.9969 3629528 CBKinase1_019439 CC(N(c1ccccc1)S(=O)(=O)C)C(=O)Nc2cc(Cl)ccc2Oc3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2384 P24 compound treatment 1560323.0 44600.0 0.08 830439.0 -584000.0 -1.17 -0.7659 -0.6547 3629529 CBKinase1_019440 O=C(Nc1ccccc1C(=O)N2CCOCC2)c3ccc(CN4CCOCC4)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A01 compound treatment 909563.0 -442000.0 -0.83 1049092.0 -386000.0 -0.77 -1.1325 -0.9993 3629530 CBKinase1_019441 CON(C)c1nc(Oc2ccc(O)nn2)nc(n1)N(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A02 compound treatment 711403.0 -641000.0 -1.2 901780.0 -533000.0 -1.07 -1.6037 -0.9982 3629531 CBKinase1_019442 CCOC(=O)c1c(NC(=S)Nc2cnccn2)sc(C)c1c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A03 compound treatment 911102.0 -441000.0 -0.83 1356401.0 -78400.0 -0.16 -0.6961 -0.8262 3629532 CBKinase1_019443 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A04 compound treatment 1063185.0 -289000.0 -0.54 1124481.0 -310000.0 -0.62 -0.822 -0.9978 3629533 CBKinase1_019444 O=C(N(CCC#N)CCC#N)c1ccco1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A05 compound treatment 1045469.0 -307000.0 -0.58 1154062.0 -281000.0 -0.56 -0.8037 -0.9999 3629534 CBKinase1_019445 CCN(CC)C(=O)c1sc(NC(=S)Nc2ccc(Br)cn2)c(C(=O)OC)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A06 compound treatment 949420.0 -403000.0 -0.76 1080480.0 -354000.0 -0.71 -1.0352 -0.9995 3629535 CBKinase1_019446 CS(=O)(=O)N(CC(=O)Nc1ccccc1C(=O)N2CCOCC2)c3cc(ccc3Cl)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A07 compound treatment 841069.0 -511000.0 -0.96 1007128.0 -428000.0 -0.85 -1.2827 -0.9983 3629536 CBKinase1_019447 Cc1nnc(SCC(=O)Nc2sc3CC(CCc3c2C#N)C(C)(C)C)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A08 compound treatment 970551.0 -382000.0 -0.72 1044148.0 -391000.0 -0.78 -1.0585 -0.9991 1231492 CBKinase1_019448 NC(=O)C1CN(C(=O)C1)c2ccc(OCC(=O)Nc3cc(Cl)cc(Cl)c3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A09 compound treatment 1079502.0 -273000.0 -0.51 1033226.0 -402000.0 -0.8 -0.9293 -0.9764 3629537 CBKinase1_019449 CCN1CCOC(CC(=O)Nc2cc(OC)cc(OC)c2)C1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A10 compound treatment 806112.0 -546000.0 -1.02 1468950.0 34200.0 0.07 -0.6764 -0.6585 3629538 CBKinase1_019450 COC(=O)c1c(C)c(C)sc1NC(=S)Nc2c(C)nn(Cc3ccc(Cl)c(Cl)c3)c2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A11 compound treatment 963606.0 -388000.0 -0.73 1238537.0 -196000.0 -0.39 -0.793 -0.9577 3629539 CBKinase1_019451 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Cl)c2ccc(I)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A12 compound treatment 1032593.0 -319000.0 -0.6 1109201.0 -326000.0 -0.65 -0.8842 -0.9992 3629540 CBKinase1_019452 CCn1c(SCC(=O)Nc2cccc(c2)C(F)(F)F)nnc1c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A13 mock treatment 912101.0 -440000.0 -0.83 1167488.0 -267000.0 -0.53 -0.9618 -0.9778 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A14 mock treatment 831967.0 -520000.0 -0.98 1173238.0 -262000.0 -0.52 -1.06 -0.9571 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A15 compound treatment 917086.0 -435000.0 -0.82 1142841.0 -292000.0 -0.58 -0.99 -0.9864 3629541 CBKinase1_019453 Cc1onc(c1C(=O)N(CCC#N)CCC#N)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A16 compound treatment 919623.0 -432000.0 -0.81 1218163.0 -217000.0 -0.43 -0.8802 -0.9567 3629542 CBKinase1_019454 CC(C)c1ccccc1NC(=O)CSc2nnc(C)s2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A17 compound treatment 825604.0 -526000.0 -0.99 1006076.0 -429000.0 -0.86 -1.3047 -0.9975 3629543 CBKinase1_019455 COC(=O)c1c(C)c(C)sc1NC(=S)Nc2ccc(cc2OC)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A18 compound treatment 840620.0 -511000.0 -0.96 998732.0 -436000.0 -0.87 -1.2951 -0.9988 3629544 CBKinase1_019456 CC(N(c1ccc(Oc2ccccc2)cc1)S(=O)(=O)C)C(=O)Nc3ccc(F)c(F)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A19 compound treatment 1082703.0 -269000.0 -0.51 1320648.0 -114000.0 -0.23 -0.5188 -0.9353 3629545 CBKinase1_019457 COc1cc(NC(=O)C2CCC(=O)N2S(=O)(=O)c3ccc(C)cc3)cc(OC)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A20 compound treatment 1034462.0 -318000.0 -0.6 1234330.0 -200000.0 -0.4 -0.7049 -0.9813 3629546 CBKinase1_019458 CCOc1ccc(NC(=S)Nc2sc3CCCc3c2C(=O)OC)c(c1)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A21 compound treatment 774575.0 -577000.0 -1.08 1091752.0 -343000.0 -0.69 -1.2514 -0.9756 3629547 CBKinase1_019459 CNc1nc(OCCNC(=O)Nc2ccccc2)nc(n1)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A22 compound treatment 878610.0 -473000.0 -0.89 1133342.0 -301000.0 -0.6 -1.0545 -0.9821 3629548 CBKinase1_019460 COC(=O)c1c(NC(=S)Nc2cc3oc4ccccc4c3cc2OC)sc5CCCCc15 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A23 compound treatment 1021460.0 -331000.0 -0.62 1047783.0 -387000.0 -0.77 -0.9858 -0.994 3629549 CBKinase1_019461 COc1cc(ccc1NC(=S)NCc2cn(nc2c3ccccc3)c4ccccc4)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 A24 compound treatment 720275.0 -632000.0 -1.19 1018921.0 -416000.0 -0.83 -1.4264 -0.9849 3629550 CBKinase1_019462 COC(=O)c1sc(NC(=S)Nc2ccn(C)n2)c(C(=O)OC)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B01 compound treatment 1153518.0 -199000.0 -0.37 1022201.0 -413000.0 -0.82 -0.8466 -0.9356 3629551 CBKinase1_019463 CCc1cc(C(=O)OC)c(NC(=S)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B02 compound treatment 960633.0 -391000.0 -0.73 1082615.0 -352000.0 -0.7 -1.0173 -0.9998 3629552 CBKinase1_019464 CC(C)(C)c1cc(ccn1)C(=O)NCc2ccco2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B03 compound treatment 973852.0 -378000.0 -0.71 1319103.0 -116000.0 -0.23 -0.6655 -0.8913 3629553 CBKinase1_019465 COc1cc(cc(OC)c1OC)c2nnn(CC(=O)Nc3ccccc3C)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B04 compound treatment 906172.0 -446000.0 -0.84 1388346.0 -46400.0 -0.09 -0.6575 -0.7807 3629554 CBKinase1_019466 O=C(CSc1nc[nH]n1)Nc2ccc(cc2)c3nc4ccccc4s3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B05 compound treatment 1355674.0 3620.0 0.01 1326294.0 -108000.0 -0.22 -0.1485 -0.6846 1452310 CBKinase1_019467 COc1ccc(CCNC(=S)N2CCN(CC2)C(=O)c3ccco3)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B06 compound treatment 1286128.0 -65900.0 -0.12 1329680.0 -105000.0 -0.21 -0.236 -0.9682 3629555 CBKinase1_019468 CCn1c(SCC(=O)Nc2cccc(SC)c2)nnc1c3cc4cc(Br)ccc4o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B07 compound treatment 958588.0 -393000.0 -0.74 1134274.0 -300000.0 -0.6 -0.947 -0.9947 3629556 CBKinase1_019469 CN(c1cccc(NC(=O)c2ccccc2N(C)S(=O)(=O)c3ccccc3)c1)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B08 compound treatment 1241127.0 -111000.0 -0.21 1220550.0 -214000.0 -0.43 -0.45 -0.9452 3629557 CBKinase1_019470 CC1(C)Cc2nc(nc(SCC(=O)Nc3ccc(Br)cc3)c2CO1)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B09 compound treatment 1115781.0 -236000.0 -0.44 1451489.0 16700.0 0.03 -0.29 -0.6519 3629558 CBKinase1_019471 Cc1nnc(SCC(=O)Nc2ccc(I)cc2C)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B10 compound treatment 802368.0 -550000.0 -1.03 948326.0 -486000.0 -0.97 -1.4172 -0.9996 3629559 CBKinase1_019472 COc1cccc(OC)c1C(=O)NC(=S)Nc2cccc(c2)c3nn4c(C)nnc4s3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B11 compound treatment 1287897.0 -64200.0 -0.12 1357112.0 -77600.0 -0.16 -0.1949 -0.9922 3629560 CBKinase1_019473 [O-][N+](=O)c1ccccc1S(=O)(=O)Nc2ccccc2C(=O)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B12 compound treatment 1146786.0 -205000.0 -0.39 1376526.0 -58200.0 -0.12 -0.3548 -0.8813 3629561 CBKinase1_019474 Clc1cccc(NC(=O)Nc2cccc(c2)S(=O)(=O)N3CCOCC3)c1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B13 mock treatment 1252103.0 -100000.0 -0.19 1367062.0 -67700.0 -0.14 -0.2284 -0.9871 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B14 mock treatment 1173863.0 -178000.0 -0.33 1379740.0 -55000.0 -0.11 -0.3143 -0.8926 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B15 compound treatment 1071617.0 -280000.0 -0.53 1639530.0 205000.0 0.41 -0.0829 -0.1243 3629562 CBKinase1_019475 COc1ccc2oc(nc2c1)c3cccc(NC(=O)COc4ccc(Cl)cc4)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B16 compound treatment 1018901.0 -333000.0 -0.63 1349476.0 -85300.0 -0.17 -0.5628 -0.8681 3629563 CBKinase1_019476 COc1ccc(NC(=O)C2CCC(=O)N2S(=O)(=O)c3ccc(C)cc3)c(OC)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B17 compound treatment 1036454.0 -316000.0 -0.59 1356870.0 -77900.0 -0.16 -0.529 -0.8636 3629564 CBKinase1_019477 Cc1nc(SCC(=O)NCC2CCCO2)c3c4CCCc4sc3n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B18 compound treatment 1034346.0 -318000.0 -0.6 1211828.0 -223000.0 -0.45 -0.7368 -0.9897 3629565 CBKinase1_019478 CN(c1ccccc1C(=O)Nc2cccnc2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B19 compound treatment 787870.0 -564000.0 -1.06 1277286.0 -157000.0 -0.31 -0.9715 -0.8792 3629566 CBKinase1_019479 COc1ccc(NC(=S)NCc2cn(nc2c3ccccc3)c4ccccc4)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B20 compound treatment 882905.0 -469000.0 -0.88 1217283.0 -217000.0 -0.43 -0.9301 -0.947 3629567 CBKinase1_019480 COc1ccc(CN2C(=O)C(O)(CC(=O)c3ccc4ccccc4c3)c5ccccc25)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B21 compound treatment 1382554.0 30500.0 0.06 1236070.0 -199000.0 -0.4 -0.2403 -0.599 3629568 CBKinase1_019481 Cc1ccc(cc1C)S(=O)(=O)N2CCN(CC2)c3ccc([N+](=O)[O-])c(NCc4ccco4)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B22 compound treatment 1179304.0 -173000.0 -0.32 1476622.0 41900.0 0.08 -0.1702 -0.508 3629569 CBKinase1_019482 COc1cc(ccc1NC(=S)Nc2nn(Cc3ccc(Cl)cc3Cl)cc2Cl)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B23 compound treatment 1010394.0 -342000.0 -0.64 1191157.0 -244000.0 -0.49 -0.7978 -0.9908 3629570 CBKinase1_019483 COC(=O)c1c(NC(=O)c2ccccc2N(C)S(=O)(=O)C)sc3CCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 B24 compound treatment 849258.0 -503000.0 -0.94 1292324.0 -142000.0 -0.28 -0.8688 -0.8812 3629571 CBKinase1_019484 COc1ccc(Cl)cc1N(CC(=O)Nc2cc(Cl)ccc2Cl)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C01 compound treatment 1524722.0 173000.0 0.32 1611589.0 177000.0 0.35 0.4791 0.9991 1495655 CBKinase1_019485 NC(=O)C1CN(C(=O)C1)c2ccc(OCC(=O)Nc3ccccc3F)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C02 compound treatment 1335949.0 -16100.0 -0.03 1658589.0 224000.0 0.45 0.295 0.6578 3629572 CBKinase1_019486 COC(=O)c1cccc(NC(=O)CN(c2ccc(I)cc2)S(=O)(=O)C)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C03 compound treatment 1420415.0 68400.0 0.13 1770066.0 335000.0 0.67 0.5646 0.8275 3629573 CBKinase1_019487 CC(Sc1nc2ccccc2c(=O)[nH]1)C(=O)Nc3cccc(Cl)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C04 compound treatment 1660734.0 309000.0 0.58 1706362.0 272000.0 0.54 0.7936 0.9995 3629574 CBKinase1_019488 CC(=O)c1cccc(NC(=O)NCc2ccco2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C05 compound treatment 1668960.0 317000.0 0.59 1722076.0 287000.0 0.57 0.8267 0.9998 3629575 CBKinase1_019489 O=S(=O)(Nc1ncccn1)c2ccc(NC(=S)N3CCN(CC3)c4ncccn4)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C06 compound treatment 1756845.0 405000.0 0.76 1831879.0 397000.0 0.79 1.0986 0.9998 3629576 CBKinase1_019490 OC(=O)C(CC(=O)Nc1cccc(Cl)c1)NC2CCCCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C07 compound treatment 1665569.0 314000.0 0.59 1758233.0 323000.0 0.65 0.8733 0.9989 3629577 CBKinase1_019491 COC(=O)c1c(C)c(sc1NC(=S)Nc2cc(OC)c(Cl)cc2OC)C(=O)N(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C08 compound treatment 1745817.0 394000.0 0.74 1906874.0 472000.0 0.94 1.1899 0.9927 3629578 CBKinase1_019492 OC1(CC(=O)c2ccccc2[N+](=O)[O-])C(=O)N(Cc3ccccc3)c4ccccc41 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C09 compound treatment 1566773.0 215000.0 0.4 1757350.0 323000.0 0.64 0.7409 0.9744 3629579 CBKinase1_019493 Cc1cc(C)c(c(C)c1)S(=O)(=O)N(CC(=O)O)Cc2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C10 compound treatment 1721300.0 369000.0 0.69 1650267.0 216000.0 0.43 0.7947 0.9738 3629580 CBKinase1_019494 Cc1cccc(c1)N(CC(=O)Nc2ccc(Cl)c(Cl)c2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C11 mock treatment 1581406.0 229000.0 0.43 1816493.0 382000.0 0.76 0.844 0.9633 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C12 mock treatment 1810919.0 459000.0 0.86 1932209.0 497000.0 0.99 1.3122 0.9974 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C13 compound treatment 1708716.0 357000.0 0.67 1901218.0 466000.0 0.93 1.1327 0.9868 3629581 CBKinase1_019495 CNc1nc(SCC(=O)N)nc(n1)N2CCOCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C14 compound treatment 1401360.0 49300.0 0.09 2160610.0 726000.0 1.45 1.0913 0.7507 3629582 CBKinase1_019496 CCc1nnc(SCC(=O)Nc2cccc(c2)[N+](=O)[O-])o1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C15 mock treatment 1652162.0 300000.0 0.56 1716527.0 282000.0 0.56 0.7966 1.0 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C16 mock treatment 1707161.0 355000.0 0.67 1727732.0 293000.0 0.59 0.8855 0.9979 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C17 compound treatment 1448728.0 96700.0 0.18 1874599.0 440000.0 0.88 0.75 0.8355 3629583 CBKinase1_019497 COc1cccc(CN2CCN(CC2)C(=S)Nc3ccc(cc3)S(=O)(=O)N)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C18 compound treatment 1378186.0 26100.0 0.05 1775904.0 341000.0 0.68 0.5168 0.756 1329385 CBKinase1_019498 COc1ccc(Cl)cc1NC(=S)NCc2cccnc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C19 compound treatment 1350071.0 -1980.0 0.0 1497798.0 63000.0 0.13 0.0865 0.6859 3629584 CBKinase1_019499 COc1ccc(NS(=O)(=O)c2ccccc2)cc1CN3C(=O)c4ccccc4C3=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C20 compound treatment 1839979.0 488000.0 0.92 1705487.0 271000.0 0.54 1.0303 0.9685 3629585 CBKinase1_019500 COc1ccc(Cl)cc1NC(=S)NCCCN2CCCC2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C21 compound treatment 1308706.0 -43300.0 -0.08 1466500.0 31700.0 0.06 -0.0127 -0.1229 3629586 CBKinase1_019501 CN(CC(=O)N1CCN(C)CC1)S(=O)(=O)c2ccc3ccccc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C22 compound treatment 1641099.0 289000.0 0.54 1661875.0 227000.0 0.45 0.7047 0.9961 1523220 CBKinase1_019502 Cc1cc(C)c(cc1C)S(=O)(=O)NC(CC(=O)O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C23 compound treatment 1486860.0 135000.0 0.25 1611264.0 177000.0 0.35 0.4284 0.9867 3629587 CBKinase1_019503 Cn1c(=O)n(CC(=O)Nc2cccnc2)c3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 C24 compound treatment 1298377.0 -53700.0 -0.1 1419702.0 -15100.0 -0.03 -0.0925 -0.8799 3629588 CBKinase1_019504 COc1ccc(OC)c(c1)S(=O)(=O)Nc2cc(ccc2C)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D01 compound treatment 1114474.0 -238000.0 -0.45 1564085.0 129000.0 0.26 -0.1326 -0.2572 3629589 CBKinase1_019505 Cc1cc(I)cc(C)c1NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D02 compound treatment 1329846.0 -22200.0 -0.04 1525687.0 90900.0 0.18 0.099 0.5311 3629590 CBKinase1_019506 COC(=O)c1cc(C)sc1NC(=S)NCCn2cc(Cl)cn2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D03 compound treatment 1030485.0 -322000.0 -0.6 1299804.0 -135000.0 -0.27 -0.6176 -0.934 3629591 CBKinase1_019507 COC(=O)c1c(NC(=S)NC(C)c2ccncc2)sc3CC(C)CCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D04 compound treatment 1532218.0 180000.0 0.34 1570503.0 136000.0 0.27 0.431 0.994 3629592 CBKinase1_019508 Cc1ccc(cc1C)C(=O)CSc2ncnc3sc4CCCc4c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D05 compound treatment 1558686.0 207000.0 0.39 1636897.0 202000.0 0.4 0.56 0.9998 3629593 CBKinase1_019509 CNc1nc(Oc2ccc(O)nn2)nc(n1)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D06 compound treatment 1132752.0 -219000.0 -0.41 1386529.0 -48200.0 -0.1 -0.3593 -0.8497 3629594 CBKinase1_019510 Cc1sc2ncn(CC(=O)Nc3cccc(c3)C(F)(F)F)c(=O)c2c1c4ccc(Cl)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D07 compound treatment 1606525.0 254000.0 0.48 1541198.0 106000.0 0.21 0.4882 0.9336 3629595 CBKinase1_019511 OC1(CC(=O)c2cccnc2)C(=O)N(Cc3cccc4ccccc34)c5ccccc51 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D08 compound treatment 1478317.0 126000.0 0.24 1465540.0 30800.0 0.06 0.2111 0.8621 3629596 CBKinase1_019512 Cc1ccccc1NC(=O)CSc2nc(N)c3c4CC(C)(C)OCc4sc3n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D09 compound treatment 974856.0 -377000.0 -0.71 1157982.0 -277000.0 -0.55 -0.8919 -0.9925 3629597 CBKinase1_019513 Cc1cc2oc3C(=O)N(CCCN4CCOCC4)C(c3c(=O)c2cc1C)c5cccc(Br)c5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D10 compound treatment 1570681.0 219000.0 0.41 1627857.0 193000.0 0.39 0.5631 0.9995 3629598 CBKinase1_019514 Clc1ccc(NC(=O)c2ccccc2NS(=O)(=O)c3cccc4cccnc34)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D11 mock treatment 1826157.0 474000.0 0.89 1928248.0 493000.0 0.99 1.3268 0.9987 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D12 mock treatment 1691046.0 339000.0 0.64 1910025.0 475000.0 0.95 1.1217 0.981 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D13 compound treatment 1634100.0 282000.0 0.53 1767520.0 333000.0 0.67 0.8447 0.9936 3629599 CBKinase1_019515 CC(C)(C)c1ccc(cc1)S(=O)(=O)NCC(=O)Nc2ccc3OCCOc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D14 compound treatment 1601743.0 250000.0 0.47 1758269.0 324000.0 0.65 0.7887 0.9875 3629600 CBKinase1_019516 COCCNC(=O)c1ccccc1NC(=O)Nc2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D15 mock treatment 1638107.0 286000.0 0.54 1704190.0 269000.0 0.54 0.7605 1.0 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D16 mock treatment 1855139.0 503000.0 0.94 1933933.0 499000.0 1.0 1.3733 0.9996 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D17 compound treatment 1674495.0 322000.0 0.61 1691749.0 257000.0 0.51 0.7912 0.9967 1180084 CBKinase1_019517 Fc1ccc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)cc1F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D18 compound treatment 1758527.0 406000.0 0.76 1612393.0 178000.0 0.36 0.7906 0.9394 3629601 CBKinase1_019518 CCOC(=O)c1c(NC(=S)Nc2cnccn2)sc3CCCCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D19 compound treatment 1521758.0 170000.0 0.32 1733322.0 299000.0 0.6 0.6472 0.9568 3629602 CBKinase1_019519 CC(=O)c1ccc(NC(=O)CSc2nnc(C)[nH]2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D20 compound treatment 1554295.0 202000.0 0.38 1555508.0 121000.0 0.24 0.4391 0.9761 3629603 CBKinase1_019520 COc1ccccc1NC(=O)CC(NC2CCCCC2)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D21 compound treatment 1517015.0 165000.0 0.31 1639674.0 205000.0 0.41 0.5086 0.9905 1449027 CBKinase1_019521 CCn1c(CSc2nc3ccccc3[nH]2)n[nH]c1=S 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D22 compound treatment 831407.0 -521000.0 -0.98 855077.0 -580000.0 -1.16 -1.5104 -0.9964 3629604 CBKinase1_019522 Oc1c(Sc2nc[nH]n2)cc(NS(=O)(=O)c3ccc(Br)cc3)c4ccccc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D23 compound treatment 1243872.0 -108000.0 -0.2 1352654.0 -82100.0 -0.16 -0.2596 -0.9944 3629605 CBKinase1_019523 CC(C)c1ccc(C)cc1OCCSc2nc(N)cc(N)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 D24 compound treatment 1001227.0 -351000.0 -0.66 1442115.0 7360.0 0.01 -0.4553 -0.6911 3629606 CBKinase1_019524 Cc1c(CCC(=O)O)c(=O)oc2c(C)c(OCc3ccccc3Cl)ccc12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E01 mock treatment 874852.0 -477000.0 -0.9 1445968.0 11200.0 0.02 -0.6176 -0.6892 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E02 mock treatment 1174797.0 -177000.0 -0.33 1435597.0 840.0 0.0 -0.2341 -0.7035 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E03 compound treatment 1366635.0 14600.0 0.03 1458306.0 23500.0 0.05 0.0526 0.9667 3629607 CBKinase1_019525 COC(=O)c1c(NC(=O)CC2NCCNC2=O)sc3CCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E04 compound treatment 1327316.0 -24700.0 -0.05 1429831.0 -4930.0 -0.01 -0.0398 -0.8384 3629608 CBKinase1_019526 Clc1cccc(c2ccc(COC(=O)c3cccnc3)o2)c1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E05 compound treatment 1431114.0 79100.0 0.15 1489587.0 54800.0 0.11 0.1824 0.9889 3629609 CBKinase1_019527 Cn1c(SCC(=O)Nc2ccc(F)cc2)nnc1c3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E06 compound treatment 1384340.0 32300.0 0.06 1485347.0 50600.0 0.1 0.1144 0.97 3629610 CBKinase1_019528 COc1ccc(NC(=O)Cn2c(C)ncc2[N+](=O)[O-])c(OC)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E07 compound treatment 1367502.0 15400.0 0.03 1311332.0 -123000.0 -0.25 -0.1539 -0.6197 3629611 CBKinase1_019529 Cn1c(S)nnc1CC(=O)Nc2ccc(Cl)c(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E08 compound treatment 1422020.0 70000.0 0.13 1444181.0 9420.0 0.02 0.1062 0.8003 3629612 CBKinase1_019530 COCC(=O)Nc1sc2CCC(C(=O)OC)c2c1C(=O)OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E09 mock treatment 1260440.0 -91600.0 -0.17 1307661.0 -127000.0 -0.25 -0.3012 -0.982 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E10 mock treatment 1432143.0 80100.0 0.15 1279564.0 -155000.0 -0.31 -0.113 -0.3279 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E11 compound treatment 1264861.0 -87200.0 -0.16 1368965.0 -65800.0 -0.13 -0.2087 -0.9941 3629613 CBKinase1_019531 COc1ccc(CCNC(=S)Nc2ccc(cc2)c3nc4ccc(C)cc4s3)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E12 compound treatment 1559682.0 208000.0 0.39 1507756.0 73000.0 0.15 0.3788 0.9101 3629614 CBKinase1_019532 Cc1nnc(SCC(=O)Nc2ccccc2N3CCOCC3)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E13 compound treatment 1400213.0 48200.0 0.09 1434341.0 -416.0 0.0 0.0633 0.7006 3629615 CBKinase1_019533 CCOC(=O)c1c(NC(=S)NCc2ccco2)sc3CCCCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E14 compound treatment 1345396.0 -6660.0 -0.01 1348403.0 -86400.0 -0.17 -0.1309 -0.7563 3629616 CBKinase1_019534 CCc1c(C)sc(NC(=S)Nc2cnccn2)c1C(=O)OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E15 compound treatment 1129136.0 -223000.0 -0.42 1278359.0 -156000.0 -0.31 -0.517 -0.9897 3629617 CBKinase1_019535 COc1ccccc1CNC(=O)c2ccc(Cl)c(c2)S(=O)(=O)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E16 compound treatment 1387567.0 35500.0 0.07 1240312.0 -194000.0 -0.39 -0.2277 -0.5774 3629618 CBKinase1_019536 COC(=O)c1c(NC(=S)NCc2ccccn2)sc3CCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E17 mock treatment 1332308.0 -19700.0 -0.04 1368134.0 -66600.0 -0.13 -0.1204 -0.8709 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E18 mock treatment 1443481.0 91400.0 0.17 1306380.0 -128000.0 -0.26 -0.0601 -0.1946 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E19 compound treatment 1562430.0 210000.0 0.39 1254303.0 -180000.0 -0.36 0.0242 0.0453 3629619 CBKinase1_019537 COC(=O)c1c(NC(=S)Nc2cccc(c2)S(=O)(=O)N3CCOCC3)sc4CCCc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E20 compound treatment 1438475.0 86400.0 0.16 1417902.0 -16900.0 -0.03 0.0909 0.5486 3629620 CBKinase1_019538 Cc1nnc(SCC(=O)Nc2ccccc2C(=O)c3ccccc3)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E21 compound treatment 1514140.0 162000.0 0.3 1209776.0 -225000.0 -0.45 -0.1028 -0.1893 3629621 CBKinase1_019539 CCn1cc(CN(C)C(=S)Nc2sc3CC(C)CCc3c2C(=O)OC)c(C)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E22 compound treatment 1187750.0 -164000.0 -0.31 1261655.0 -173000.0 -0.35 -0.4628 -0.9984 3629622 CBKinase1_019540 CC(=O)c1cccc(c1)n2nnnc2SCC(=O)Nc3ccccc3F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E23 compound treatment 293579.0 -1060000.0 -1.99 304211.0 -1130000.0 -2.26 -3.0029 -0.9979 3629623 CBKinase1_019541 Cc1ccc2nsnc2c1S(=O)(=O)Nc3cccc4cccnc34 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 E24 compound treatment 873731.0 -478000.0 -0.9 1359974.0 -74800.0 -0.15 -0.7407 -0.8136 1986210 CBKinase1_019542 CCn1c2nnc(SC(C)C(=O)O)n2c3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F01 mock treatment 1192714.0 -159000.0 -0.3 1366682.0 -68100.0 -0.14 -0.3077 -0.9364 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F02 mock treatment 1403868.0 51800.0 0.1 1411898.0 -22900.0 -0.05 0.0365 0.3394 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F03 compound treatment 1255711.0 -96300.0 -0.18 1642487.0 208000.0 0.42 0.1657 0.3659 3629624 CBKinase1_019543 CCOc1ccc(NC(=O)CC2NC3CCCCC3NC2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F04 compound treatment 1307743.0 -44300.0 -0.08 1304714.0 -130000.0 -0.26 -0.2426 -0.889 3629625 CBKinase1_019544 CC1(C)Cc2nc3sc4c(SCC(=O)NCc5ccccc5)ncnc4c3cc2CO1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F05 compound treatment 1377780.0 25700.0 0.05 1474349.0 39600.0 0.08 0.0901 0.9719 3629626 CBKinase1_019545 COc1ccc(cc1)C(=O)NCCNc2ccccc2[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F06 compound treatment 1594607.0 243000.0 0.46 1727456.0 293000.0 0.59 0.7356 0.9923 1720489 CBKinase1_019546 Fc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccc(I)cc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F07 compound treatment 1441008.0 89000.0 0.17 1360814.0 -73900.0 -0.15 0.0136 0.0609 3629627 CBKinase1_019547 CCn1ccc(CNC(=O)Nc2cccc(c2)C(F)(F)F)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F08 compound treatment 1662456.0 310000.0 0.58 1421942.0 -12800.0 -0.03 0.3939 0.6754 3629628 CBKinase1_019548 CC(C)(C)c1cc(NC(=O)CSc2nnnn2c3ccccc3)cc(c1)C(C)(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F09 mock treatment 1569790.0 218000.0 0.41 1787100.0 352000.0 0.7 0.787 0.9665 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F10 mock treatment 1571514.0 219000.0 0.41 1556409.0 122000.0 0.24 0.4633 0.9684 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F11 compound treatment 1641120.0 289000.0 0.54 1530936.0 96200.0 0.19 0.5197 0.9026 3629629 CBKinase1_019549 CCOc1ccccc1NC(=S)NCc2ccco2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F12 compound treatment 1684970.0 333000.0 0.62 1472446.0 37700.0 0.08 0.4952 0.7866 1435710 CBKinase1_019550 Cc1c(NC(=S)NCCc2c[nH]c3ccccc23)c(=O)n(c4ccccc4)n1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F13 compound treatment 1549891.0 198000.0 0.37 1601534.0 167000.0 0.33 0.4983 0.9985 3629630 CBKinase1_019551 CN(C)S(=O)(=O)c1ccc(NC(=O)CCC(=O)O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F14 compound treatment 1498709.0 147000.0 0.28 1166521.0 -268000.0 -0.54 -0.1844 -0.306 3629631 CBKinase1_019552 Cc1cc(C)c(C)c(OCC(O)Cn2cnc3ccccc23)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F15 compound treatment 1747920.0 396000.0 0.74 1586163.0 151000.0 0.3 0.7395 0.9216 1757005 CBKinase1_019553 Cn1c(SCC(=O)NC(C)(C)C)nnc1c2ccco2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F16 compound treatment 1521632.0 170000.0 0.32 1455197.0 20400.0 0.04 0.254 0.7914 3629632 CBKinase1_019554 COc1ccc(NC(=O)CC(N2CCCCC2)C(=O)O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F17 mock treatment 1708519.0 356000.0 0.67 1649040.0 214000.0 0.43 0.776 0.9767 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F18 mock treatment 1489310.0 137000.0 0.26 1631550.0 197000.0 0.39 0.4603 0.979 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F19 compound treatment 1349602.0 -2450.0 0.0 1372514.0 -62200.0 -0.12 -0.0912 -0.7328 3629633 CBKinase1_019555 CCS(=O)(=O)c1nc2ccccc2n1CCOc3ccc(OC)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F20 compound treatment 1527701.0 176000.0 0.33 1578007.0 143000.0 0.29 0.4356 0.9975 2068310 CBKinase1_019556 CN(C)C(CC(=O)Nc1cc(Cl)ccc1C)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F21 compound treatment 1574718.0 223000.0 0.42 1576248.0 141000.0 0.28 0.4955 0.9819 3629634 CBKinase1_019557 COc1ccccc1NC(=O)CC2NC3CCCCC3NC2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F22 compound treatment 1240154.0 -112000.0 -0.21 1442376.0 7620.0 0.02 -0.1378 -0.6541 3629635 CBKinase1_019558 CSc1ccccc1NC(=O)CN(c2ccc(C)c(Cl)c2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F23 compound treatment 1249650.0 -102000.0 -0.19 1701126.0 266000.0 0.53 0.2405 0.4249 3629636 CBKinase1_019559 CS(=O)(=O)N(CC(=O)Nc1ccc(F)c(F)c1)c2ccc(Cl)c(c2)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 F24 compound treatment 1253842.0 -98200.0 -0.18 1557678.0 123000.0 0.25 0.0433 0.1411 3211239 CBKinase1_019560 CCS(=O)(=O)c1nnnn1c2ccccc2S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G01 compound treatment 1265160.0 -86900.0 -0.16 1386810.0 -47900.0 -0.1 -0.1831 -0.9678 3629637 CBKinase1_019561 COCCNC(=O)c1ccccc1NC(=O)c2ccco2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G02 compound treatment 1251998.0 -100000.0 -0.19 1489001.0 54200.0 0.11 -0.0562 -0.2589 3629638 CBKinase1_019562 CN1CCN(CC1)C(CC(=O)Nc2ccc(Cl)cc2)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G03 mock treatment 1202001.0 -150000.0 -0.28 1593214.0 158000.0 0.32 0.0248 0.0584 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G04 mock treatment 1236907.0 -115000.0 -0.22 1477557.0 42800.0 0.09 -0.0924 -0.3973 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G05 compound treatment 1493328.0 141000.0 0.27 1602507.0 168000.0 0.34 0.4246 0.9933 3629639 CBKinase1_019563 CC(Sc1nc(N)cc(N)n1)C(=O)Nc2cccc(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G06 compound treatment 1268209.0 -83800.0 -0.16 1811304.0 377000.0 0.75 0.4209 0.5474 3629640 CBKinase1_019564 Cc1c(NC(=O)CSc2nncc3ccccc23)c(=O)n(c4ccccc4)n1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G07 compound treatment 1429816.0 77800.0 0.15 1508422.0 73700.0 0.15 0.2073 1.0 3629641 CBKinase1_019565 Fc1ccc(NC(=O)CC2N(CCNC2=O)C(=S)Nc3ccccc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G08 compound treatment 1456203.0 104000.0 0.2 1832743.0 398000.0 0.8 0.7007 0.8555 3629642 CBKinase1_019566 COC(=O)c1sc(NC(=S)Nc2cccc(Cn3cc(Cl)cn3)c2)c(C(=O)OC)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G09 compound treatment 1674891.0 323000.0 0.61 1808432.0 374000.0 0.75 0.9567 0.9946 3629643 CBKinase1_019567 FC(F)(F)c1ccccc1NC(=O)NCCCn2cc(Br)cn2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G10 compound treatment 1790069.0 438000.0 0.82 1981770.0 547000.0 1.09 1.3545 0.9901 3629644 CBKinase1_019568 COc1ccc(NC(=O)NC(C)c2cn(C)nc2C)c(OC)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G11 compound treatment 1774334.0 422000.0 0.79 1767797.0 333000.0 0.67 1.0312 0.9962 3629645 CBKinase1_019569 Cc1ccc(SCC(=O)Nc2ccccc2C(=O)N3CCOCC3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G12 compound treatment 1877243.0 525000.0 0.99 1602172.0 167000.0 0.33 0.9338 0.8968 3629646 CBKinase1_019570 Cn1c(SCC(=O)Nc2ccc(N3CCOCC3)c(Cl)c2)nc4n(C)c(=O)n(C)c(=O)c14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G13 compound treatment 1586248.0 234000.0 0.44 1926523.0 492000.0 0.98 1.0059 0.9342 3629647 CBKinase1_019571 Oc1nc(SCC(=O)N(c2ccccc2)c3ccccc3)[nH]c(=O)c1c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G14 compound treatment 1811316.0 459000.0 0.86 1729139.0 294000.0 0.59 1.0257 0.9826 3629648 CBKinase1_019572 CSc1ccccc1n2nnnc2SCC(=O)Nc3cc(C)ccc3C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G15 compound treatment 1881466.0 529000.0 0.99 1731496.0 297000.0 0.59 1.1222 0.9696 3629649 CBKinase1_019573 COC(=O)c1c(C)c(sc1NC(=S)NCc2ccccn2)C(=O)N(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G16 compound treatment 1809379.0 457000.0 0.86 1794504.0 360000.0 0.72 1.1155 0.9961 3629650 CBKinase1_019574 CCn1c2nnc(SCC(=O)Nc3ccc(Cl)cc3)n2c4ccccc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G17 compound treatment 1853120.0 501000.0 0.94 1610134.0 175000.0 0.35 0.913 0.9095 3629651 CBKinase1_019575 CS(=O)(=O)N(CC(=O)Nc1ccc(cc1)C(F)(F)F)c2ccc(I)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G18 compound treatment 1593530.0 241000.0 0.45 1311102.0 -124000.0 -0.25 0.1458 0.2824 3629652 CBKinase1_019576 FC(F)(F)c1ccc(NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G19 mock treatment 1625856.0 274000.0 0.51 1629833.0 195000.0 0.39 0.6392 0.9907 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G20 mock treatment 1529106.0 177000.0 0.33 1229253.0 -206000.0 -0.41 -0.0554 -0.1049 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G21 compound treatment 1079496.0 -273000.0 -0.51 1316854.0 -118000.0 -0.24 -0.5284 -0.9381 3629653 CBKinase1_019577 COC(=O)c1c(NC(=S)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3)sc4CC(C)CCc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G22 compound treatment 1406424.0 54400.0 0.1 1591179.0 156000.0 0.31 0.2932 0.8916 3629654 CBKinase1_019578 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccncc3)S(=O)(=O)c4ccc(F)cc4C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G23 compound treatment 1528967.0 177000.0 0.33 1597477.0 163000.0 0.33 0.4648 0.9999 3629655 CBKinase1_019579 [O-][N+](=O)c1cccc(NC(=S)NCCn2cc(Br)cn2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 G24 compound treatment 1298662.0 -53400.0 -0.1 1285151.0 -150000.0 -0.3 -0.2823 -0.8952 3629656 CBKinase1_019580 OC(=O)C(CC(=O)Nc1cccc2ccccc12)N3CCCCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H01 compound treatment 1004656.0 -347000.0 -0.65 1344285.0 -90500.0 -0.18 -0.589 -0.8703 3629657 CBKinase1_019581 CC(C)c1ccc(C)cc1OCCSc2ncnc3[nH]cnc23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H02 compound treatment 1548376.0 196000.0 0.37 1706734.0 272000.0 0.54 0.645 0.9821 3629658 CBKinase1_019582 Cc1n[nH]c(C)c1C(=O)CC2(O)C(=O)N(Cc3ccccc3)c4ccccc42 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H03 mock treatment 1407942.0 55900.0 0.1 1678660.0 244000.0 0.49 0.4189 0.8401 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H04 mock treatment 1471343.0 119000.0 0.22 1754904.0 320000.0 0.64 0.6108 0.901 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H05 compound treatment 1718748.0 367000.0 0.69 1771619.0 337000.0 0.67 0.9629 0.9999 3629659 CBKinase1_019583 COC(=O)c1ccccc1NC(=O)NC(C)c2cc(OC)ccc2OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H06 compound treatment 1441479.0 89400.0 0.17 1425520.0 -9240.0 -0.02 0.1057 0.6256 3629660 CBKinase1_019584 Cc1ccc(cc1)c2csc3nnc(SCC(=O)Nc4ccc(Cl)cc4)n23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H07 compound treatment 1718180.0 366000.0 0.69 1785918.0 351000.0 0.7 0.9823 0.9999 3629661 CBKinase1_019585 COc1cc(NC(=O)C(C)N2C(=O)C3CC=C(Cl)CC3C2=O)ccc1[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H08 compound treatment 1327225.0 -24800.0 -0.05 1783216.0 348000.0 0.7 0.4595 0.6583 3629662 CBKinase1_019586 COC(=O)c1sccc1NC(=O)COc2ccc(cc2)C(=O)OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H09 compound treatment 1876975.0 525000.0 0.99 1868242.0 433000.0 0.87 1.3095 0.9979 3629663 CBKinase1_019587 CCc1c(C)sc(NC(=S)Nc2cc(OC)c(Cl)cc2OC)c1C(=O)OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H10 compound treatment 1856322.0 504000.0 0.95 1385305.0 -49500.0 -0.1 0.5995 0.6299 3629664 CBKinase1_019588 Clc1cnn(Cc2cccc(NC(=S)NCC3CCCO3)c2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H11 compound treatment 1910326.0 558000.0 1.05 1992689.0 558000.0 1.12 1.5296 0.9995 3629665 CBKinase1_019589 [O-][N+](=O)c1ccccc1NC(=O)CC2NCCNC2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H12 compound treatment 1805353.0 453000.0 0.85 1914921.0 480000.0 0.96 1.2804 0.9982 3629666 CBKinase1_019590 O=C(CN1C(=O)c2ccccc2C1=O)Oc3ccc(cc3)C(=O)Nc4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H13 compound treatment 1814158.0 462000.0 0.87 1974432.0 540000.0 1.08 1.3761 0.9942 3629667 CBKinase1_019591 COC(=O)c1cc(OC)c(OC)cc1NC(=O)Cn2nnc(n2)c3ccccc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H14 compound treatment 1733722.0 382000.0 0.72 1816922.0 382000.0 0.76 1.0468 0.9995 3629668 CBKinase1_019592 Cc1ccc(cc1C)N(Cc2ccc(cc2)C(=O)Nc3cc(ccc3C)[N+](=O)[O-])S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H15 compound treatment 1699467.0 347000.0 0.65 1791872.0 357000.0 0.71 0.9659 0.999 3629669 CBKinase1_019593 Cc1c(O)nc(SCC(=O)Nc2cccc(c2)C(F)(F)F)n(c3ccccc3)c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H16 compound treatment 1843097.0 491000.0 0.92 1909160.0 474000.0 0.95 1.3223 0.9999 3629670 CBKinase1_019594 Cc1c(CNC(=S)Nc2cccc(c2)[N+](=O)[O-])cnn1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H17 compound treatment 1743679.0 392000.0 0.74 1690213.0 255000.0 0.51 0.8809 0.9841 3629671 CBKinase1_019595 COc1cc(ccc1NC(=S)NCc2ccccn2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H18 compound treatment 1615539.0 263000.0 0.49 1608141.0 173000.0 0.35 0.5948 0.9849 3629672 CBKinase1_019596 COc1ccc(CN2C(=O)C(O)(CC(=O)c3ccco3)c4ccccc24)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H19 mock treatment 1623635.0 272000.0 0.51 1722113.0 287000.0 0.57 0.7666 0.9982 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H20 mock treatment 1637331.0 285000.0 0.54 1443963.0 9210.0 0.02 0.3917 0.731 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H21 compound treatment 1569130.0 217000.0 0.41 1714930.0 280000.0 0.56 0.6841 0.9878 3629673 CBKinase1_019597 COC(=O)c1c(NC(=S)Nc2cc3oc4ccccc4c3cc2OC)sc5CCCc15 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H22 compound treatment 1479323.0 127000.0 0.24 1481895.0 47100.0 0.09 0.2356 0.9172 3629674 CBKinase1_019598 COC(=O)c1c(NC(=S)N2CCN(Cc3c(C)nn(C)c3C)CC2)sc4CC(C)CCc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H23 compound treatment 1485164.0 133000.0 0.25 1555425.0 121000.0 0.24 0.3472 0.9998 3629675 CBKinase1_019599 CC(NS(=O)(=O)c1ccc(C)c(C)c1)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 H24 compound treatment 1486894.0 135000.0 0.25 1336301.0 -98500.0 -0.2 0.0399 0.1243 3629676 CBKinase1_019600 [O-][N+](=O)c1ccccc1CC(=O)Nc2ccccc2C(=O)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I01 compound treatment 1223696.0 -128000.0 -0.24 1267471.0 -167000.0 -0.33 -0.4068 -0.9871 3629677 CBKinase1_019601 CCOC(=O)c1c(NC(=S)Nc2cnn(CC)c2C(=O)N)sc3CCCCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I02 compound treatment 973898.0 -378000.0 -0.71 1777470.0 343000.0 0.68 -0.0176 -0.0179 3629678 CBKinase1_019602 CSc1ccccc1NC(=O)Cn2c(nc3ccccc23)c4nonc4N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I03 compound treatment 1224103.0 -128000.0 -0.24 1582971.0 148000.0 0.3 0.0396 0.1039 3629679 CBKinase1_019603 Cc1ccc(Cl)cc1N(CC(=O)Nc2c(F)cccc2F)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I04 compound treatment 1505032.0 153000.0 0.29 1301011.0 -134000.0 -0.27 0.0141 0.0358 3629680 CBKinase1_019604 O=S(=O)(Nc1ccc(cc1)S(=O)(=O)Nc2nccs2)c3cccs3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I05 mock treatment 1571641.0 220000.0 0.41 1635946.0 201000.0 0.4 0.5758 0.9999 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I06 mock treatment 1501182.0 149000.0 0.28 1651906.0 217000.0 0.43 0.5049 0.9775 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I07 compound treatment 1321820.0 -30200.0 -0.06 1463777.0 29000.0 0.06 9.0E-4 0.0108 3119005 CBKinase1_019605 OC(=O)CSc1ncnc2scc(c3ccc(Br)cc3)c12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I08 compound treatment 1135761.0 -216000.0 -0.41 1212142.0 -223000.0 -0.44 -0.6017 -0.999 3629681 CBKinase1_019606 CSc1ccccc1NC(=O)C(C)N(c2ccccc2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I09 compound treatment 1469883.0 118000.0 0.22 1534966.0 100000.0 0.2 0.298 0.9988 3629682 CBKinase1_019607 CN(CC(=O)Nc1ccc(F)c(Cl)c1)S(=O)(=O)c2ccc3ccccc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I10 compound treatment 1555491.0 203000.0 0.38 1476786.0 42000.0 0.08 0.3295 0.8425 1984280 CBKinase1_019608 COc1cccc(NC(=O)CC2OCCN(Cc3ccccc3)C2=O)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I11 compound treatment 1424180.0 72100.0 0.14 1674185.0 239000.0 0.48 0.4341 0.8729 3629683 CBKinase1_019609 CCN1CCOC(CC(=O)Nc2ccc3OCCOc3c2)C1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I12 compound treatment 1510100.0 158000.0 0.3 1187993.0 -247000.0 -0.49 -0.1389 -0.2414 3629684 CBKinase1_019610 COCCNC(=O)c1ccccc1NC(=O)c2ccccc2OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I13 compound treatment 1734037.0 382000.0 0.72 1516079.0 81300.0 0.16 0.622 0.8459 3629685 CBKinase1_019611 CSc1ccccc1NC(=O)CN(c2cccc(c2)[N+](=O)[O-])S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I14 compound treatment 1473956.0 122000.0 0.23 1627953.0 193000.0 0.39 0.4349 0.9688 3629686 CBKinase1_019612 CC(Sc1nc(N)cc(=O)[nH]1)C(=O)Nc2cccc(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I15 compound treatment 1525857.0 174000.0 0.33 1480782.0 46000.0 0.09 0.2958 0.8725 3629687 CBKinase1_019613 CSc1ccccc1NC(=O)CN(c2cccc3ccccc23)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I16 compound treatment 1375048.0 23000.0 0.04 1569361.0 135000.0 0.27 0.2208 0.8102 3629688 CBKinase1_019614 Cc1ccc(cc1)S(=O)(=O)N2C(CCC2=O)C(=O)Nc3ccc(I)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I17 compound treatment 1414978.0 62900.0 0.12 1420715.0 -14000.0 -0.03 0.0637 0.5245 3629689 CBKinase1_019615 Cc1cccc(c1)n2c(N)cc(=O)nc2SCC(=O)N(c3ccccc3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I18 compound treatment 1412994.0 60900.0 0.11 1268508.0 -166000.0 -0.33 -0.1541 -0.4384 3629690 CBKinase1_019616 [O-][N+](=O)c1ccc(cc1)c2nnc(SCC(=O)Nc3ccccc3Cl)n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I19 compound treatment 1534060.0 182000.0 0.34 1278930.0 -156000.0 -0.31 0.0214 0.0462 3629691 CBKinase1_019617 Fc1ccc(cc1)C(=O)n2nc(nc2NCc3ccco3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I20 compound treatment 1419269.0 67200.0 0.13 1313279.0 -121000.0 -0.24 -0.0825 -0.3013 3629692 CBKinase1_019618 COc1ccc(NC(=S)NCCn2cc(Br)cn2)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I21 mock treatment 1542383.0 190000.0 0.36 1419451.0 -15300.0 -0.03 0.231 0.6442 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I22 mock treatment 1357189.0 5130.0 0.01 1506767.0 72000.0 0.14 0.1086 0.7528 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I23 compound treatment 1170656.0 -181000.0 -0.34 1302435.0 -132000.0 -0.26 -0.4278 -0.9922 3629693 CBKinase1_019619 Cc1c(Cl)cccc1NC(=O)Nc2cccc(Cn3cccn3)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 I24 compound treatment 985238.0 -367000.0 -0.69 1546262.0 112000.0 0.22 -0.3294 -0.455 3629694 CBKinase1_019620 COc1ccc(NC(=O)NCc2cc(C)n(C)n2)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J01 compound treatment 881411.0 -471000.0 -0.88 1052371.0 -382000.0 -0.76 -1.1652 -0.9974 3629695 CBKinase1_019621 COc1cc2c(cc1NC(=O)CCCOc3ccccc3)oc4ccccc42 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J02 compound treatment 1159880.0 -192000.0 -0.36 1274197.0 -161000.0 -0.32 -0.482 -0.9983 3629696 CBKinase1_019622 COc1ccc(NC(=O)CN2CCN(CC2)S(=O)(=O)c3c(C)cc(C)cc3C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J03 compound treatment 1106991.0 -245000.0 -0.46 1371157.0 -63600.0 -0.13 -0.4152 -0.8699 3629697 CBKinase1_019623 CSc1ccccc1NC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J04 compound treatment 1324475.0 -27600.0 -0.05 1294851.0 -140000.0 -0.28 -0.2343 -0.824 3629698 CBKinase1_019624 O=C(Cn1cnc2scc(c3ccccc3)c2c1=O)Nc4sc5CCCc5c4C#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J05 mock treatment 1481415.0 129000.0 0.24 1641276.0 207000.0 0.41 0.4636 0.968 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J06 mock treatment 1369857.0 17800.0 0.03 1560359.0 126000.0 0.25 0.2011 0.7942 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J07 compound treatment 1479077.0 127000.0 0.24 1536535.0 102000.0 0.2 0.3125 0.9969 3629699 CBKinase1_019625 COc1ccc(Cl)cc1NC(=S)NCCn2cc(Cl)cn2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J08 compound treatment 1446717.0 94700.0 0.18 1321572.0 -113000.0 -0.23 -0.0343 -0.1192 3629700 CBKinase1_019626 Cn1c(SCC(=O)Nc2sc3CCCCc3c2C#N)nnc1c4ccc(Br)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J09 compound treatment 1395620.0 43600.0 0.08 1544889.0 110000.0 0.22 0.2135 0.9091 3629701 CBKinase1_019627 CN(C)C(CC(=O)Nc1ccc(C)cc1)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J10 compound treatment 1707793.0 356000.0 0.67 1818224.0 383000.0 0.77 1.0142 0.9976 3629702 CBKinase1_019628 Cc1c(CCC(=O)O)c(=O)oc2cc(OCC(=O)O)ccc12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J11 compound treatment 1510673.0 159000.0 0.3 1445910.0 11200.0 0.02 0.2263 0.7579 3629703 CBKinase1_019629 CCc1c(O)nc(SC(C)C(=O)Nc2cccc(Cl)c2)[nH]c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J12 compound treatment 1535617.0 184000.0 0.34 1597341.0 163000.0 0.32 0.4735 0.9996 3629704 CBKinase1_019630 COC(=O)c1sc(NC(=S)Nc2c(C)nn(Cc3c(F)c(F)c(F)c(F)c3F)c2C)c(C(=O)OC)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J13 compound treatment 1548503.0 196000.0 0.37 1475399.0 40600.0 0.08 0.3182 0.8427 3629705 CBKinase1_019631 CCCOc1ccc(cc1)c2nnc(SCC(=O)O)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J14 compound treatment 1493998.0 142000.0 0.27 1478976.0 44200.0 0.09 0.2509 0.8938 1744796 CBKinase1_019632 Oc1cc(=O)[nH]c(SCC(=O)N(c2ccccc2)c3ccccc3)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J15 compound treatment 1557333.0 205000.0 0.39 1481327.0 46600.0 0.09 0.3383 0.8534 3629706 CBKinase1_019633 COc1ccccc1NC(=O)Cn2nnc3sc4CC(C)CCc4c3c2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J16 compound treatment 1456949.0 105000.0 0.2 1618183.0 183000.0 0.37 0.3985 0.9575 3629707 CBKinase1_019634 COc1ccc(NC(=O)CC2NCCNC2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J17 compound treatment 1326163.0 -25900.0 -0.05 1462405.0 27600.0 0.06 0.0047 0.0639 3629708 CBKinase1_019635 COC(=O)c1ccc(C(=O)OC)c(NC(=O)CN2C(=O)c3cccc4cccc2c34)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J18 compound treatment 1535036.0 183000.0 0.34 1475298.0 40500.0 0.08 0.3002 0.8506 3629709 CBKinase1_019636 COC(=O)c1c(C)c(C)sc1NC(=S)Nc2ccc(CC(=O)O)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J19 compound treatment 1469330.0 117000.0 0.22 1226892.0 -208000.0 -0.42 -0.1381 -0.2937 3629710 CBKinase1_019637 Cn1c(SCC(=O)Nc2c(F)cc(F)cc2Br)nnc1c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J20 compound treatment 835547.0 -517000.0 -0.97 970389.0 -464000.0 -0.93 -1.3419 -0.9998 3629711 CBKinase1_019638 COc1cc(c(OC)cc1Br)S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J21 mock treatment 1325771.0 -26300.0 -0.05 1392388.0 -42400.0 -0.08 -0.0948 -0.967 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J22 mock treatment 1229302.0 -123000.0 -0.23 1413187.0 -21600.0 -0.04 -0.1934 -0.8251 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J23 compound treatment 1076203.0 -276000.0 -0.52 1205604.0 -229000.0 -0.46 -0.69 -0.9981 3629712 CBKinase1_019639 OC(=O)CSc1cc(NS(=O)(=O)c2cccc3cccnc23)c4ccccc4c1O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 J24 compound treatment 1211043.0 -141000.0 -0.26 1395027.0 -39700.0 -0.08 -0.2433 -0.8805 3629713 CBKinase1_019640 Clc1cccc(c1)C(=O)Nc2cccc(NC(=O)c3nc[nH]n3)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K01 compound treatment 989048.0 -363000.0 -0.68 921387.0 -513000.0 -1.03 -1.2074 -0.9802 3629714 CBKinase1_019641 CS(=O)(=O)N(CC(=O)Nc1ccccc1C(=O)N2CCOCC2)c3cccc(F)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K02 compound treatment 1097176.0 -255000.0 -0.48 879496.0 -555000.0 -1.11 -1.1231 -0.9293 3629715 CBKinase1_019642 CS(=O)(=O)N1CCN(CC1)C(=S)NCc2ccco2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K03 compound treatment 1114931.0 -237000.0 -0.45 1315672.0 -119000.0 -0.24 -0.4831 -0.957 3629716 CBKinase1_019643 CSc1ccccc1n2nnnc2SCC(=O)Nc3ccccc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K04 compound treatment 1230886.0 -121000.0 -0.23 1225619.0 -209000.0 -0.42 -0.4564 -0.9591 3629717 CBKinase1_019644 C(Nc1ncnc2c1sc3nc(N4CCCCC4)c5CCCCc5c32)C6CCCO6 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K05 compound treatment 920343.0 -432000.0 -0.81 1006476.0 -428000.0 -0.86 -1.1784 -0.9996 3629718 CBKinase1_019645 CCOc1ccc(OCC)c(c1)S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K06 compound treatment 918443.0 -434000.0 -0.81 1430757.0 -4000.0 -0.01 -0.5813 -0.714 3629719 CBKinase1_019646 S=C(NCc1ccco1)N2CCN(CC2)c3ncccn3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K07 mock treatment 1414135.0 62100.0 0.12 1435064.0 307.0 0.0 0.0828 0.7108 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K08 mock treatment 1370607.0 18600.0 0.03 1328338.0 -106000.0 -0.21 -0.1258 -0.5835 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K09 compound treatment 1436559.0 84500.0 0.16 1389189.0 -45600.0 -0.09 0.0478 0.2612 3629720 CBKinase1_019647 Cc1nn(C)c(C)c1CN2CCN(CC2)C(=S)Nc3ccc(cc3)S(=O)(=O)N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K10 compound treatment 1338510.0 -13500.0 -0.03 1386036.0 -48700.0 -0.1 -0.0868 -0.8628 3629721 CBKinase1_019648 CN1CCN(CC1)C(CC(=O)Nc2cccc(c2)[N+](=O)[O-])C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K11 compound treatment 1492087.0 140000.0 0.26 1551685.0 117000.0 0.23 0.3511 0.9983 3629722 CBKinase1_019649 COc1ccc(C)cc1NC(=O)c2ccccc2NS(=O)(=O)c3cccc4cccnc34 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K12 compound treatment 1192234.0 -160000.0 -0.3 1441643.0 6890.0 0.01 -0.2024 -0.674 3629723 CBKinase1_019650 COC(=O)c1c(NC(=S)NCc2cn(nc2c3ccccc3)c4ccccc4)sc5CCCc15 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K13 compound treatment 1399413.0 47400.0 0.09 934650.0 -500000.0 -1.0 -0.6439 -0.6417 3629724 CBKinase1_019651 COc1ccc(C)cc1NC(=O)NCc2cc(C)n(C)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K14 compound treatment 1062755.0 -289000.0 -0.54 1389101.0 -45700.0 -0.09 -0.4486 -0.8145 3629725 CBKinase1_019652 Cc1ccc(C)c(c1)n2nnnc2SCC(=O)Nc3ccc(F)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K15 mock treatment 1383497.0 31400.0 0.06 1237119.0 -198000.0 -0.4 -0.2376 -0.5948 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K16 mock treatment 1443743.0 91700.0 0.17 1169379.0 -265000.0 -0.53 -0.2533 -0.4543 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K17 compound treatment 1368465.0 16400.0 0.03 1031653.0 -403000.0 -0.81 -0.5479 -0.6796 3629726 CBKinase1_019653 COC(=O)c1c(C)c(C)sc1NC(=S)Nc2cccc(NC(=O)C)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K18 compound treatment 1012935.0 -339000.0 -0.64 972681.0 -462000.0 -0.92 -1.1032 -0.9835 3629727 CBKinase1_019654 COC(=O)c1sc(NC(=S)Nc2ccc(Cl)cn2)c(C(=O)OC)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K19 compound treatment 1241309.0 -111000.0 -0.21 1397266.0 -37500.0 -0.07 -0.2 -0.905 3629728 CBKinase1_019655 Nc1ncnc2[nH]c(SCC(=O)N3CCN(CC3)c4ccccc4)nc12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K20 compound treatment 1324277.0 -27800.0 -0.05 1330807.0 -104000.0 -0.21 -0.1838 -0.858 3629729 CBKinase1_019656 CN(c1ccccc1C(=O)Nc2ccccc2C(=O)N3CCOCC3)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K21 compound treatment 1410547.0 58500.0 0.11 1326640.0 -108000.0 -0.22 -0.0752 -0.31 3629730 CBKinase1_019657 Cc1sc(NC(=O)COc2c(C)cccc2C)c(C(=O)N)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K22 compound treatment 1296428.0 -55600.0 -0.1 1396393.0 -38400.0 -0.08 -0.1281 -0.9885 3629731 CBKinase1_019658 Cc1cc(=O)oc2cc(NC(=S)NCCCN3CCCC3=O)ccc12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K23 mock treatment 1132978.0 -219000.0 -0.41 1374205.0 -60600.0 -0.12 -0.3764 -0.878 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 K24 mock treatment 1190224.0 -162000.0 -0.3 1277763.0 -157000.0 -0.31 -0.4367 -0.9999 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L01 compound treatment 851037.0 -501000.0 -0.94 1190508.0 -244000.0 -0.49 -1.0103 -0.9533 3629732 CBKinase1_019659 O=S(=O)(Nc1ncccn1)c2ccc(NC(=S)Nc3ccc4OCCOc4c3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L02 compound treatment 977284.0 -375000.0 -0.7 1252405.0 -182000.0 -0.36 -0.7552 -0.9531 3629733 CBKinase1_019660 Nc1nc(nn1C(=O)c2ccco2)c3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L03 compound treatment 1222414.0 -130000.0 -0.24 1269276.0 -165000.0 -0.33 -0.406 -0.9886 3629734 CBKinase1_019661 COc1ccc(OC)c(c1)N(CC(=O)Nc2ccc(F)c(F)c2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L04 compound treatment 1133578.0 -218000.0 -0.41 1147264.0 -287000.0 -0.57 -0.6963 -0.9863 3629735 CBKinase1_019662 COc1ccc(OCC(=O)Nc2cc(ccc2C)c3nn4c(C)nnc4s3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L05 compound treatment 1219294.0 -133000.0 -0.25 1334150.0 -101000.0 -0.2 -0.3184 -0.9943 3629736 CBKinase1_019663 COc1ccc(NC(=O)Cc2c(OC)ccc3cc(Br)ccc23)c(OC)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L06 compound treatment 1375692.0 23600.0 0.04 1444596.0 9840.0 0.02 0.0453 0.933 3629737 CBKinase1_019664 Cc1ccc(cc1)c2csc3nnc(SCC(=O)Nc4nsc(n4)c5ccccc5)n23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L07 mock treatment 1429006.0 77000.0 0.14 1333790.0 -101000.0 -0.2 -0.0405 -0.1634 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L08 mock treatment 1378642.0 26600.0 0.05 1136409.0 -298000.0 -0.6 -0.3864 -0.6457 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L09 compound treatment 1287421.0 -64600.0 -0.12 1341628.0 -93100.0 -0.19 -0.2174 -0.9785 3629738 CBKinase1_019665 CCCN1C(=O)C(O)(CC(=O)c2ccc(OC)c(c2)[N+](=O)[O-])c3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L10 compound treatment 1143882.0 -208000.0 -0.39 1433955.0 -802.0 0.0 -0.2775 -0.71 1627303 CBKinase1_019666 CCSc1nc2ccccc2n1C(CC(=O)O)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L11 compound treatment 1404574.0 52500.0 0.1 1494617.0 59900.0 0.12 0.1543 0.9954 3629739 CBKinase1_019667 Fc1ccc(NC(=O)CC2NC3CCCCC3NC2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L12 compound treatment 1436265.0 84200.0 0.16 1309501.0 -125000.0 -0.25 -0.0652 -0.2203 3629740 CBKinase1_019668 COC(=O)c1ccc(NC(=O)CN(c2ccc(C)cc2C)S(=O)(=O)C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L13 compound treatment 1351856.0 -199.0 0.0 1445375.0 10600.0 0.02 0.0147 0.6945 3629741 CBKinase1_019669 C(Sc1nnc(c2ccncc2)n1c3ccccc3)c4nc5ccccc5s4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L14 compound treatment 1421830.0 69800.0 0.13 1515352.0 80600.0 0.16 0.2065 0.9947 3629742 CBKinase1_019670 CCn1c2nnc(SCCC(=O)O)n2c3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L15 mock treatment 1319900.0 -32200.0 -0.06 1381600.0 -53200.0 -0.11 -0.1178 -0.9641 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L16 mock treatment 1278039.0 -74000.0 -0.14 1303876.0 -131000.0 -0.26 -0.2832 -0.9562 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L17 compound treatment 1249483.0 -103000.0 -0.19 1343301.0 -91500.0 -0.18 -0.2654 -0.9997 3629743 CBKinase1_019671 COC(=O)c1c(NC(=S)Nc2c(C)nn(Cc3c(F)c(F)c(F)c(F)c3F)c2C)sc(C)c1c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L18 compound treatment 1300169.0 -51900.0 -0.1 1389586.0 -45200.0 -0.09 -0.1327 -0.9993 3629744 CBKinase1_019672 Cc1ccc(NC(=O)CC2NCCNC2=O)cc1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L19 compound treatment 1297535.0 -54500.0 -0.1 1348928.0 -85800.0 -0.17 -0.1937 -0.9695 3629745 CBKinase1_019673 CCN1CCOC(CC(=O)Nc2cc(cc(c2)C(=O)OC)C(=O)OC)C1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L20 compound treatment 1394882.0 42800.0 0.08 1386904.0 -47900.0 -0.1 -0.0108 -0.0863 3629746 CBKinase1_019674 CSc1ccccc1NC(=O)CSc2nnnn2c3ccccc3F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L21 compound treatment 1157822.0 -194000.0 -0.36 1181252.0 -254000.0 -0.51 -0.6161 -0.987 3629747 CBKinase1_019675 COC(=O)c1ccccc1NC(=O)Nc2nn(Cc3ccc(Cl)c(Cl)c3)cc2Br 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L22 compound treatment 1480633.0 129000.0 0.24 1436292.0 1540.0 0.0 0.1729 0.716 1219753 CBKinase1_019676 COC(=O)Cc1csc(Nc2c(C)n(C)n(c3ccccc3)c2=O)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L23 mock treatment 1116480.0 -236000.0 -0.44 1163180.0 -272000.0 -0.54 -0.6965 -0.9948 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 L24 mock treatment 1130457.0 -222000.0 -0.42 1269513.0 -165000.0 -0.33 -0.5277 -0.9935 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M01 compound treatment 1033550.0 -319000.0 -0.6 1065006.0 -370000.0 -0.74 -0.9454 -0.9945 3629748 CBKinase1_019677 CS(=O)(=O)N(CC(=O)Nc1c(F)cccc1F)c2cccc(Br)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M02 compound treatment 1166113.0 -186000.0 -0.35 1091445.0 -343000.0 -0.69 -0.732 -0.9509 3629749 CBKinase1_019678 COC(=O)c1cccc(NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M03 compound treatment 1112149.0 -240000.0 -0.45 1156242.0 -279000.0 -0.56 -0.7121 -0.9945 3629750 CBKinase1_019679 COc1ccc(NC(=S)NCc2ccccn2)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M04 compound treatment 1114544.0 -238000.0 -0.45 1225524.0 -209000.0 -0.42 -0.611 -0.9995 3629751 CBKinase1_019680 COc1cc(ccc1NC(=O)Nc2nn(Cc3ccc(Cl)c(Cl)c3)cc2Cl)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M05 compound treatment 1250784.0 -101000.0 -0.19 1179286.0 -255000.0 -0.51 -0.4955 -0.9094 3629752 CBKinase1_019681 COC(=O)c1ccccc1NC(=O)NCC2CCCO2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M06 compound treatment 1388822.0 36800.0 0.07 1260779.0 -174000.0 -0.35 -0.1971 -0.5559 3629753 CBKinase1_019682 Fc1ccccc1NC(=O)CSc2nnc(o2)c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M07 compound treatment 1142899.0 -209000.0 -0.39 1189330.0 -245000.0 -0.49 -0.6245 -0.9939 3629754 CBKinase1_019683 CC(=O)c1cccc(NC(=S)NCCn2cc(Cl)cn2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M08 compound treatment 1117914.0 -234000.0 -0.44 1221601.0 -213000.0 -0.43 -0.6121 -0.9999 3629755 CBKinase1_019684 Fc1ccc(NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M09 mock treatment 1238025.0 -114000.0 -0.21 1335453.0 -99300.0 -0.2 -0.2917 -0.9993 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M10 mock treatment 1328947.0 -23100.0 -0.04 1237941.0 -197000.0 -0.39 -0.3088 -0.7804 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M11 compound treatment 1298268.0 -53800.0 -0.1 1306356.0 -128000.0 -0.26 -0.2529 -0.9169 3629756 CBKinase1_019685 COC(=O)c1c(NC(=S)Nc2cccnc2)sc3CCCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M12 compound treatment 1333532.0 -18500.0 -0.03 1198209.0 -237000.0 -0.47 -0.3589 -0.7571 3629757 CBKinase1_019686 CSc1cccc(NC(=O)CSc2nnc(c3cccc(C)c3)n2c4ccccc4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M13 mock treatment 1349650.0 -2410.0 0.0 1351954.0 -82800.0 -0.17 -0.1202 -0.7261 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M14 mock treatment 1143547.0 -209000.0 -0.39 1216387.0 -218000.0 -0.44 -0.5854 -0.9985 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M15 compound treatment 1324691.0 -27400.0 -0.05 1208888.0 -226000.0 -0.45 -0.3555 -0.7825 3629758 CBKinase1_019687 Cc1ccc(cc1NC(=O)CN(c2ccccc2F)S(=O)(=O)C)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M16 compound treatment 1279547.0 -72500.0 -0.14 1235943.0 -199000.0 -0.4 -0.3772 -0.8981 3629759 CBKinase1_019688 COc1ccccc1C(=O)n2nc(nc2NCc3ccco3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M17 compound treatment 1308181.0 -43900.0 -0.08 1253210.0 -182000.0 -0.36 -0.3148 -0.8461 3629760 CBKinase1_019689 CSc1ccccc1NC(=O)Cn2c(C)ncc2[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M18 compound treatment 1178772.0 -173000.0 -0.33 1185597.0 -249000.0 -0.5 -0.5822 -0.9787 3629761 CBKinase1_019690 O=C(CC1NCCNC1=O)Nc2ccc(Oc3ccccc3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M19 compound treatment 1328631.0 -23400.0 -0.04 1250703.0 -184000.0 -0.37 -0.2912 -0.786 3629762 CBKinase1_019691 CCCNC(=O)c1ccccc1NC(=O)C2COc3ccccc3O2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M20 compound treatment 1276489.0 -75600.0 -0.14 1410109.0 -24600.0 -0.05 -0.1351 -0.8999 3629763 CBKinase1_019692 COC(=O)c1sccc1NC(=S)Nc2sc3CC(C)CCc3c2C(=O)OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M21 compound treatment 1128129.0 -224000.0 -0.42 1186709.0 -248000.0 -0.5 -0.6478 -0.9966 3629764 CBKinase1_019693 COc1ccc(cc1NC(=O)c2ccccc2N(C)S(=O)(=O)c3ccc(C)cc3)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M22 compound treatment 1059860.0 -292000.0 -0.55 1032065.0 -403000.0 -0.8 -0.957 -0.9825 3629765 CBKinase1_019694 COC(=O)c1sc(NC(=S)NCc2cccnc2)c(C(=O)OC)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M23 compound treatment 1274397.0 -77700.0 -0.15 1305498.0 -129000.0 -0.26 -0.2858 -0.9633 3629766 CBKinase1_019695 COc1ccc(Cl)cc1NC(=S)NCc2ccc(cc2)S(=O)(=O)N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 M24 compound treatment 1299214.0 -52800.0 -0.1 1335566.0 -99200.0 -0.2 -0.2103 -0.9488 3629767 CBKinase1_019696 Cc1cccc(C)c1OCC(=O)Nc2ccccc2C#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N01 compound treatment 942385.0 -410000.0 -0.77 1103955.0 -331000.0 -0.66 -1.0113 -0.9972 3629768 CBKinase1_019697 Cc1cc(F)ccc1NC(=S)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N02 compound treatment 1208726.0 -143000.0 -0.27 1261628.0 -173000.0 -0.35 -0.4349 -0.9923 3629769 CBKinase1_019698 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2cc(ccc2C)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N03 compound treatment 1041348.0 -311000.0 -0.58 1276947.0 -158000.0 -0.32 -0.6355 -0.9583 3629770 CBKinase1_019699 CCc1c(C)sc(NC(=S)Nc2cccc(c2)S(=O)(=O)N3CCOCC3)c1C(=O)OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N04 compound treatment 1085858.0 -266000.0 -0.5 1275514.0 -159000.0 -0.32 -0.5784 -0.9763 3629771 CBKinase1_019700 OC(=O)COc1ccc(cc1Cl)S(=O)(=O)NC2CCCCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N05 compound treatment 1137428.0 -215000.0 -0.4 1195654.0 -239000.0 -0.48 -0.6228 -0.9964 3629772 CBKinase1_019701 COC(=O)c1c(NC(=S)Nc2ccc(cc2)S(=O)(=O)NC3(CC4CC5CC(C4)C3)C5)sc6CCCc16 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N06 compound treatment 1296748.0 -55300.0 -0.1 1304999.0 -130000.0 -0.26 -0.2568 -0.9193 3629773 CBKinase1_019702 OC(=O)Cn1cc(C(=O)c2cccs2)c3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N07 compound treatment 1123003.0 -229000.0 -0.43 1363228.0 -71500.0 -0.14 -0.4052 -0.8941 3629774 CBKinase1_019703 O=C(CSc1nnc(o1)c2ccncc2)c3ccc4ccccc4c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N08 compound treatment 1186158.0 -166000.0 -0.31 1232722.0 -202000.0 -0.4 -0.5058 -0.9918 3629775 CBKinase1_019704 CC(C)C1Cc2c(CO1)sc3nc(SCC(=O)Nc4ccc(Cl)cc4Cl)nc(N)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N09 mock treatment 1255248.0 -96800.0 -0.18 1331620.0 -103000.0 -0.21 -0.2743 -0.998 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N10 mock treatment 1134569.0 -217000.0 -0.41 1300131.0 -135000.0 -0.27 -0.479 -0.9795 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N11 compound treatment 1195531.0 -157000.0 -0.29 1331884.0 -103000.0 -0.21 -0.3532 -0.9847 3629776 CBKinase1_019705 COC(=O)c1c(NC(=S)Nc2ccc(OC)cc2[N+](=O)[O-])sc3CC(C)CCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N12 compound treatment 1394970.0 42900.0 0.08 1429341.0 -5420.0 -0.01 0.0493 0.6067 3629777 CBKinase1_019706 COc1c(Cl)cc(cc1Cl)C(=O)Nc2sc3CCCCc3c2C(=O)NCc4ccco4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N13 mock treatment 1325992.0 -26100.0 -0.05 1431133.0 -3620.0 -0.01 -0.0397 -0.803 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N14 mock treatment 1215810.0 -136000.0 -0.26 1332391.0 -102000.0 -0.2 -0.3255 -0.9939 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N15 compound treatment 1272341.0 -79700.0 -0.15 1227886.0 -207000.0 -0.41 -0.3982 -0.9055 3629778 CBKinase1_019707 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N16 compound treatment 1242809.0 -109000.0 -0.21 1112189.0 -323000.0 -0.64 -0.6009 -0.8882 3629779 CBKinase1_019708 COC(=O)c1ccc(NS(=O)(=O)c2ccc3N=C(O)C(Cl)(Cl)c3c2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N17 compound treatment 1169659.0 -182000.0 -0.34 1196170.0 -239000.0 -0.48 -0.5793 -0.9868 3629780 CBKinase1_019709 [O-][N+](=O)c1ccccc1CC(=O)Nc2cc(Cl)ccc2Oc3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N18 compound treatment 1292123.0 -59900.0 -0.11 1179714.0 -255000.0 -0.51 -0.44 -0.8429 3629781 CBKinase1_019710 CC(=O)c1cccc(NC(=O)NCc2cccnc2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N19 compound treatment 1494716.0 143000.0 0.27 1447408.0 12700.0 0.03 0.2073 0.7704 3629782 CBKinase1_019711 CS(=O)(=O)N(CC(=O)Nc1ccc(F)c(F)c1)c2cccc(c2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N20 compound treatment 1201199.0 -151000.0 -0.28 1114511.0 -320000.0 -0.64 -0.6529 -0.9328 3629783 CBKinase1_019712 Cc1nc(SCC(=O)N2c3ccccc3Sc4ccccc24)nc5CCCCc15 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N21 compound treatment 1296776.0 -55300.0 -0.1 1226536.0 -208000.0 -0.42 -0.3677 -0.8572 3629784 CBKinase1_019713 O=C(CSc1nc(c(C#N)c(=O)[nH]1)c2ccccc2)N(c3ccccc3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N22 compound treatment 1302017.0 -50000.0 -0.09 1281230.0 -154000.0 -0.31 -0.2834 -0.8831 3629785 CBKinase1_019714 CCOC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccncc3)S(=O)(=O)c4ccc(F)cc4C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N23 compound treatment 1206593.0 -145000.0 -0.27 1231877.0 -203000.0 -0.41 -0.4798 -0.9815 3629786 CBKinase1_019715 CSc1ccccc1NC(=O)CN(c2ccc(I)cc2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 N24 compound treatment 1257780.0 -94300.0 -0.18 1191597.0 -243000.0 -0.49 -0.4688 -0.9064 3629787 CBKinase1_019716 COC(=O)Cn1c2sc(C)nc2c3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O01 compound treatment 685660.0 -666000.0 -1.25 760674.0 -674000.0 -1.35 -1.8373 -0.9993 3629788 CBKinase1_019717 COC(=O)c1c(NC(=S)NCc2ccc(cc2)S(=O)(=O)N)sc3CC(C)CCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O02 compound treatment 692450.0 -660000.0 -1.24 1004869.0 -430000.0 -0.86 -1.4832 -0.9841 3629789 CBKinase1_019718 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)CC2CSc3nc4ccccc4n23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O03 compound treatment 768037.0 -584000.0 -1.1 1077584.0 -357000.0 -0.71 -1.2801 -0.9784 3629790 CBKinase1_019719 COc1ccc2cc(Br)ccc2c1CC(=O)Nc3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O04 compound treatment 979238.0 -373000.0 -0.7 780949.0 -654000.0 -1.31 -1.4189 -0.9572 3629791 CBKinase1_019720 CS(=O)(=O)N(CC(=O)Nc1cccc(Cl)c1Cl)c2cccc(F)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O05 compound treatment 742336.0 -610000.0 -1.14 1178424.0 -256000.0 -0.51 -1.1717 -0.9343 3629792 CBKinase1_019721 COC(=O)c1ccccc1NC(=O)NCCc2ccccc2OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O06 compound treatment 900550.0 -452000.0 -0.85 826907.0 -608000.0 -1.21 -1.4584 -0.9845 3629793 CBKinase1_019722 COc1ccc(NC(=S)Nc2cccc(Cn3nc(C)c(Br)c3C)c2)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O07 compound treatment 703426.0 -649000.0 -1.22 740794.0 -694000.0 -1.39 -1.8418 -0.9979 3629794 CBKinase1_019723 COc1ccc(NC(=O)NCc2ccccn2)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O08 compound treatment 789724.0 -562000.0 -1.06 849778.0 -585000.0 -1.17 -1.5732 -0.9987 3629795 CBKinase1_019724 CCc1cc(C(=O)OC)c(NC(=S)Nc2cn(CC)nc2C(=O)N)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O09 compound treatment 769740.0 -582000.0 -1.09 1302522.0 -132000.0 -0.26 -0.9599 -0.8535 3629796 CBKinase1_019725 CCn1cc(NC(=S)Nc2sc3CC(C)CCc3c2C(=O)OC)c(n1)C(=O)N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O10 compound treatment 731493.0 -621000.0 -1.17 910591.0 -524000.0 -1.05 -1.5646 -0.9986 3629797 CBKinase1_019726 [O-][N+](=O)c1cccc(NC(=S)NCCn2cc(Cl)cn2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O11 mock treatment 816471.0 -536000.0 -1.01 915537.0 -519000.0 -1.04 -1.4448 -0.9999 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O12 mock treatment 991661.0 -360000.0 -0.68 998957.0 -436000.0 -0.87 -1.0943 -0.9922 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O13 compound treatment 816602.0 -535000.0 -1.01 967088.0 -468000.0 -0.93 -1.3718 -0.9993 3629798 CBKinase1_019727 Cc1ccc(cc1C)S(=O)(=O)Nc2c(C)nc(O)nc2O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O14 compound treatment 777289.0 -575000.0 -1.08 884219.0 -551000.0 -1.1 -1.5411 -1.0 3629799 CBKinase1_019728 CS(=O)(=O)N(CC(=O)Nc1ccc(Br)cc1F)c2ccccc2Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O15 compound treatment 736384.0 -616000.0 -1.16 814574.0 -620000.0 -1.24 -1.6938 -0.9994 3629800 CBKinase1_019729 CCN(CC)C(=O)c1sc(NC(=S)Nc2nc(C)cc(C)n2)c(C(=O)OC)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O16 compound treatment 750413.0 -602000.0 -1.13 742671.0 -692000.0 -1.38 -1.7768 -0.9949 3629801 CBKinase1_019730 OC(=O)C(CC(=O)Nc1ccc(Cl)cc1)N2CCOCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O17 compound treatment 772607.0 -579000.0 -1.09 801195.0 -634000.0 -1.27 -1.6646 -0.9971 3629802 CBKinase1_019731 COc1ccc(OC)c(c1)C(C)NC(=O)Nc2cccc(c2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O18 compound treatment 750183.0 -602000.0 -1.13 845964.0 -589000.0 -1.18 -1.6311 -0.9998 3629803 CBKinase1_019732 COc1cc(c(OC)cc1Cl)S(=O)(=O)Nc2cccc(c2)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O19 compound treatment 811544.0 -541000.0 -1.01 995170.0 -440000.0 -0.88 -1.3388 -0.9974 3629804 CBKinase1_019733 Cc1nnc(SCC(=O)N(c2ccccc2)c3ccccc3)[nH]1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O20 compound treatment 1019533.0 -333000.0 -0.62 961247.0 -474000.0 -0.95 -1.1106 -0.9796 1726419 CBKinase1_019734 Cc1[nH]c2ccc(cc2c1CC(=O)O)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O21 compound treatment 802339.0 -550000.0 -1.03 889863.0 -545000.0 -1.09 -1.4998 -0.9996 3629805 CBKinase1_019735 CC(NS(=O)(=O)c1ccc(Br)cc1)C(=O)Nc2cccc(c2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O22 compound treatment 750040.0 -602000.0 -1.13 989818.0 -445000.0 -0.89 -1.428 -0.993 3629806 CBKinase1_019736 Cc1n[nH]c(C)c1C(=O)CC2(O)C(=O)Nc3ccc(Br)cc32 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O23 compound treatment 730890.0 -621000.0 -1.17 1041068.0 -394000.0 -0.79 -1.381 -0.9817 3629807 CBKinase1_019737 COc1ccc(NC(=S)N2CCNC(=O)C2CC(=O)Nc3ccc(C)cc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 O24 compound treatment 727263.0 -625000.0 -1.17 1008932.0 -426000.0 -0.85 -1.4312 -0.9876 3629808 CBKinase1_019738 CCCCn1c(SCC(=O)O)nc2ccccc12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P01 compound treatment 753035.0 -599000.0 -1.12 759824.0 -675000.0 -1.35 -1.7491 -0.9959 3629809 CBKinase1_019739 Cc1cc(CNC(=S)Nc2ccc(cc2)S(=O)(=O)N)nn1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P02 compound treatment 658440.0 -694000.0 -1.3 801281.0 -633000.0 -1.27 -1.816 -0.9999 3629810 CBKinase1_019740 [O-][N+](=O)c1ccccc1OCC(=O)Nc2ccc3oc(=O)ccc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P03 compound treatment 876202.0 -476000.0 -0.89 796192.0 -639000.0 -1.28 -1.5342 -0.9848 3629811 CBKinase1_019741 CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2cccc(c2)C(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P04 compound treatment 722246.0 -630000.0 -1.18 1032754.0 -402000.0 -0.8 -1.4042 -0.9823 3629812 CBKinase1_019742 CCn1nnc(NC(=O)COc2ccc(Cl)cc2C)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P05 compound treatment 679035.0 -673000.0 -1.26 1005264.0 -429000.0 -0.86 -1.5004 -0.9823 3629813 CBKinase1_019743 Cc1cc(CNC(=O)Nc2cccc(c2)[N+](=O)[O-])nn1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P06 compound treatment 775637.0 -576000.0 -1.08 1050091.0 -385000.0 -0.77 -1.3088 -0.986 3629814 CBKinase1_019744 Cc1ccc(cc1C)n2ncc(C(=O)NCCN3CCOCC3)c2NC(=O)c4ccco4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P07 compound treatment 676357.0 -676000.0 -1.27 985756.0 -449000.0 -0.9 -1.5315 -0.9856 3629815 CBKinase1_019745 COc1ccccc1n2nnnc2SCC(=O)Nc3ccccc3SC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P08 compound treatment 727356.0 -625000.0 -1.17 941188.0 -494000.0 -0.99 -1.5268 -0.9963 3629816 CBKinase1_019746 Cn1c(SCC(=O)Nc2cccc(c2)C(=O)O)nnc1c3cc4cc(Br)ccc4o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P09 compound treatment 719618.0 -632000.0 -1.19 868167.0 -567000.0 -1.13 -1.6403 -0.9997 3629817 CBKinase1_019747 CN(CC(=O)Nc1cc(Cl)ccc1Oc2ccccc2)S(=O)(=O)c3ccc(C)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P10 compound treatment 757981.0 -594000.0 -1.12 864243.0 -571000.0 -1.14 -1.5949 -0.9999 3629818 CBKinase1_019748 Cc1nn2c(CN3CCOCC3)nnc2c4cc(ccc14)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P11 mock treatment 776701.0 -575000.0 -1.08 784794.0 -650000.0 -1.3 -1.6824 -0.9958 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P12 mock treatment 868472.0 -484000.0 -0.91 1124251.0 -311000.0 -0.62 -1.0808 -0.9828 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P13 compound treatment 827851.0 -524000.0 -0.98 911349.0 -523000.0 -1.05 -1.4356 -0.9995 3629819 CBKinase1_019749 COC(=O)c1ccc(CSc2nnc([nH]2)c3ccccc3OC)o1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P14 compound treatment 790320.0 -562000.0 -1.05 819334.0 -615000.0 -1.23 -1.6155 -0.9971 3629820 CBKinase1_019750 CCc1c(C)sc(NC(=S)Nc2cc(ccc2OC)[N+](=O)[O-])c1C(=O)OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P15 compound treatment 731874.0 -620000.0 -1.16 996022.0 -439000.0 -0.88 -1.4433 -0.9902 3629821 CBKinase1_019751 Cn1c(SCc2nc(no2)c3ccc(Br)cc3)nnc1c4ccco4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P16 compound treatment 676159.0 -676000.0 -1.27 949435.0 -485000.0 -0.97 -1.5831 -0.9912 3629822 CBKinase1_019752 COC(=O)c1c(NC(=S)Nc2cc(OC)c(OC)cc2C(=O)OC)sc3CCCCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P17 compound treatment 904782.0 -447000.0 -0.84 850023.0 -585000.0 -1.17 -1.4201 -0.9868 3629823 CBKinase1_019753 COC(=O)c1cc(C)sc1NC(=S)Nc2cnn(Cc3cccc4ccccc34)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P18 compound treatment 745831.0 -606000.0 -1.14 973270.0 -461000.0 -0.92 -1.457 -0.9946 3629824 CBKinase1_019754 COc1ccc(OCC(=O)Nc2ccc(c3nc4ccccc4s3)c(Cl)c2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P19 compound treatment 620110.0 -732000.0 -1.37 893004.0 -542000.0 -1.08 -1.7373 -0.993 3629825 CBKinase1_019755 COc1ccc(Cl)cc1NC(=O)N(C)Cc2c(C)nn(C)c2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P20 compound treatment 908685.0 -443000.0 -0.83 1080610.0 -354000.0 -0.71 -1.0891 -0.9967 3629826 CBKinase1_019756 Clc1ccc(cc1)c2nnc(SCC(=O)Nc3sc4CCCCc4c3C#N)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P21 compound treatment 879241.0 -473000.0 -0.89 1015580.0 -419000.0 -0.84 -1.2201 -0.9996 3629827 CBKinase1_019757 CSc1ccccc1NC(=O)CN(c2cccc(C)c2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P22 compound treatment 613263.0 -739000.0 -1.39 693543.0 -741000.0 -1.48 -2.0283 -0.9995 3629828 CBKinase1_019758 CCOc1ccc(Br)cc1S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P23 compound treatment 829511.0 -523000.0 -0.98 1067562.0 -367000.0 -0.73 -1.2126 -0.9898 3629829 CBKinase1_019759 O=C(CN1C(=O)c2cccc3cccc1c23)Nc4ccc(cc4)S(=O)(=O)N5CCCC5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2385 P24 compound treatment 723835.0 -628000.0 -1.18 813720.0 -621000.0 -1.24 -1.7117 -0.9997 3629830 CBKinase1_019760 CC(=O)c1cccc(NC(=O)NCc2cnn(C)c2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A01 compound treatment 1225191.0 -599000.0 -1.12 1105678.0 -258000.0 -0.52 -1.1597 -0.9376 3630121 CBKinase1_020081 CCc1cc2c(=O)n(CC(=O)Nc3ccccc3OC)cnc2s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A02 compound treatment 1355732.0 -468000.0 -0.88 1134252.0 -230000.0 -0.46 -0.946 -0.9541 3630122 CBKinase1_020082 O=C(Nc1ccccc1C(=O)N2CCOCC2)C3CCCO3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A03 compound treatment 1693503.0 -130000.0 -0.24 1224697.0 -139000.0 -0.28 -0.3698 -0.998 3630123 CBKinase1_020083 Cc1ccc(NC(=O)CC2NC3CCCCC3NC2=O)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A04 compound treatment 1743394.0 -80500.0 -0.15 1356281.0 -7570.0 -0.02 -0.1176 -0.774 3630124 CBKinase1_020084 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)NC2CCCCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A05 compound treatment 1737523.0 -86400.0 -0.16 1280598.0 -83300.0 -0.17 -0.2324 -0.9999 3630125 CBKinase1_020085 COc1cc(OC)c(NC(=O)CSc2nnnn2c3ccccc3)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A06 compound treatment 1688946.0 -135000.0 -0.25 1103767.0 -260000.0 -0.52 -0.5468 -0.9455 1756992 CBKinase1_020086 Cn1c(SCC(=O)N2CCc3ccccc23)nnc1c4ccco4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A07 compound treatment 1402796.0 -421000.0 -0.79 936525.0 -427000.0 -0.85 -1.163 -0.9993 3630126 CBKinase1_020087 COc1cccc(NC(=O)CSc2nnc(c3ccco3)n2c4ccccc4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A08 compound treatment 1736499.0 -87400.0 -0.16 1588858.0 225000.0 0.45 0.2019 0.4218 3630127 CBKinase1_020088 Clc1ccc(cc1)c2nc(NC(=O)CSc3nc[nH]n3)ns2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A09 compound treatment 1883769.0 59800.0 0.11 1344024.0 -19800.0 -0.04 0.0514 0.4315 3630128 CBKinase1_020089 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)NC3CCCCC3)cc2)no1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A10 compound treatment 2047009.0 223000.0 0.42 1481527.0 118000.0 0.24 0.4624 0.9628 3630129 CBKinase1_020090 OC(=O)C1(CCCCC1)NS(=O)(=O)c2ccc(F)c(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A11 compound treatment 1502079.0 -322000.0 -0.6 1383974.0 20100.0 0.04 -0.3988 -0.6586 3630130 CBKinase1_020091 COC(=O)c1cc(NC(=S)NCc2cccnc2)cc(c1)C(=O)OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A12 compound treatment 1714236.0 -110000.0 -0.21 1385599.0 21700.0 0.04 -0.1149 -0.5459 3630131 CBKinase1_020092 CCn1c(SCC(=O)Nc2ccc(C)cc2C)nnc1c3cccs3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A13 mock treatment 1818858.0 -5070.0 -0.01 1252213.0 -112000.0 -0.22 -0.1645 -0.7366 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A14 mock treatment 1854745.0 30800.0 0.06 1671919.0 308000.0 0.62 0.4763 0.7702 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A15 compound treatment 1835590.0 11700.0 0.02 1431793.0 67900.0 0.14 0.1115 0.8106 1263574 CBKinase1_020093 COC(=O)c1ccccc1NC(=O)Cn2nnc(n2)c3ccc(OC)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A16 compound treatment 1378242.0 -446000.0 -0.84 837954.0 -526000.0 -1.05 -1.3349 -0.9936 3630132 CBKinase1_020094 CCC(Oc1nc2ccccc2nc1c3ccccc3NC(=O)C)C(=O)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A17 compound treatment 1866193.0 42300.0 0.08 1313881.0 -50000.0 -0.1 -0.0145 -0.1139 3630133 CBKinase1_020095 NC(=O)CSc1nnc(c2ccco2)n1CC=C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A18 compound treatment 1541591.0 -282000.0 -0.53 1491174.0 127000.0 0.25 -0.1949 -0.3314 3630134 CBKinase1_020096 COc1ccc(C)cc1NC(=O)c2ccc(OCC(=O)Nc3ccccc3C(F)(F)F)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A19 compound treatment 1483335.0 -341000.0 -0.64 1587489.0 224000.0 0.45 -0.1361 -0.1744 3630135 CBKinase1_020097 COc1ccc(NC(=O)CCSc2nnc3scc(c4ccc(C)cc4)n23)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A20 compound treatment 1663963.0 -160000.0 -0.3 979445.0 -384000.0 -0.77 -0.7556 -0.916 3630136 CBKinase1_020098 Nc1nc(SCC(=O)N2CCC(CC2)c3noc4ccc(F)cc34)n[nH]1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A21 compound treatment 1781226.0 -42700.0 -0.08 1361223.0 -2630.0 -0.01 -0.0604 -0.7519 3630137 CBKinase1_020099 Cn1c(SCC(=O)Nc2ccc(I)cc2)nnc1c3cc4ccccc4o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A22 compound treatment 1323624.0 -500000.0 -0.94 1102151.0 -262000.0 -0.52 -1.034 -0.9618 3630138 CBKinase1_020100 Cc1ccc(cc1C)C(=O)CSc2ncnc3sc4CCCCc4c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A23 compound treatment 1586953.0 -237000.0 -0.44 1329818.0 -34000.0 -0.07 -0.3627 -0.8059 3630139 CBKinase1_020101 Cc1c(Cl)cccc1NC(=O)CN2CCC(CC2)(N3CCCCC3)C(=O)N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 A24 compound treatment 1066321.0 -758000.0 -1.42 952455.0 -411000.0 -0.82 -1.5871 -0.9661 3630140 CBKinase1_020102 CCOc1ccc(cc1CSc2nc(C)cc(O)n2)C(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B01 compound treatment 1711905.0 -112000.0 -0.21 1368975.0 5120.0 0.01 -0.1415 -0.6719 1803614 CBKinase1_020103 CCOC(=O)c1ccc(NC(=O)C(C)Sc2nc3ccccc3[nH]2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B02 compound treatment 1457434.0 -366000.0 -0.69 1156259.0 -208000.0 -0.41 -0.7799 -0.9707 3630141 CBKinase1_020104 [O-][N+](=O)c1cccc(c1)c2csc3ncn(CC(=O)Nc4cccc(c4)C(F)(F)F)c(=O)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B03 compound treatment 1528426.0 -296000.0 -0.55 1351906.0 -11900.0 -0.02 -0.4092 -0.7369 3630142 CBKinase1_020105 CC(=O)Nc1ccc(cc1)c2nnc(SCC(=O)Nc3cc(Cl)cc(Cl)c3)n2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B04 compound treatment 1790512.0 -33400.0 -0.06 1643630.0 280000.0 0.56 0.351 0.6239 3630143 CBKinase1_020106 OC(=O)CSc1nc2cc(F)c(cc2[nH]1)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B05 compound treatment 1872717.0 48800.0 0.09 1513769.0 150000.0 0.3 0.2766 0.8829 3630144 CBKinase1_020107 Cc1cccc(c1)N2C(=O)CC(SCC(=O)Nc3ccccc3)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B06 compound treatment 2136503.0 313000.0 0.59 1720730.0 357000.0 0.71 0.9193 0.9953 3630145 CBKinase1_020108 Cc1ccc(C)c(c1)S(=O)(=O)NCC(=O)Nc2ccc(F)c(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B07 compound treatment 2153442.0 330000.0 0.62 1377381.0 13500.0 0.03 0.4565 0.7373 3630146 CBKinase1_020109 NC(=O)C1(CCN(CC1)C(=S)NCc2ccco2)N3CCCCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B08 compound treatment 1826100.0 2170.0 0.0 1588932.0 225000.0 0.45 0.321 0.7135 1986207 CBKinase1_020110 Cc1nccn1CCc2nc(N)nc(N)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B09 compound treatment 1779116.0 -44800.0 -0.08 1500125.0 136000.0 0.27 0.1331 0.4669 3630147 CBKinase1_020111 Cc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccc(Cl)cc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B10 compound treatment 1924468.0 101000.0 0.19 1875183.0 511000.0 1.02 0.8561 0.8238 3630148 CBKinase1_020112 CCN(CC)CCNc1ncnc2scc(c3ccc(F)cc3)c12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B11 compound treatment 1900597.0 76700.0 0.14 1536134.0 172000.0 0.34 0.3453 0.9251 3630149 CBKinase1_020113 COc1ccc(cc1)c2csc(Cc3nc(cs3)c4cc5ccccc5oc4=O)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B12 compound treatment 2116886.0 293000.0 0.55 1684659.0 321000.0 0.64 0.8423 0.9971 3630150 CBKinase1_020114 COc1cccc(c1)S(=O)(=O)NCc2ccc(cc2)C(=O)Nc3ccc4sc(C)nc4c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B13 mock treatment 2107085.0 283000.0 0.53 1485885.0 122000.0 0.24 0.5483 0.9376 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B14 mock treatment 1899242.0 75300.0 0.14 1792062.0 428000.0 0.86 0.7052 0.8129 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B15 compound treatment 1770456.0 -53500.0 -0.1 1441017.0 77200.0 0.15 0.0381 0.2069 3630151 CBKinase1_020115 CC(=O)C1=C(NC(=S)NC1c2cc(Cl)ccc2OCC(=O)O)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B16 compound treatment 1453686.0 -370000.0 -0.7 997499.0 -366000.0 -0.73 -1.0093 -0.9997 3630152 CBKinase1_020116 COc1cc(OC)c(NC(=O)CSc2nnc(c3ccncc3)n2c4ccccc4)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B17 compound treatment 1542733.0 -281000.0 -0.53 1036252.0 -328000.0 -0.65 -0.8363 -0.9943 3630153 CBKinase1_020117 C(c1nnc2sc(nn12)C3COc4ccccc4O3)c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B18 compound treatment 1711422.0 -113000.0 -0.21 1543433.0 180000.0 0.36 0.1044 0.2508 3630154 CBKinase1_020118 FC(F)(F)c1nc2ccccc2n1CC(=O)NCCN3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B19 compound treatment 1598643.0 -225000.0 -0.42 1451190.0 87300.0 0.17 -0.1756 -0.3839 3630155 CBKinase1_020119 [O-][N+](=O)c1cccc2C(=O)N(CCC(=O)Oc3ccc(cc3Br)c4ccccc4)C(=O)c21 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B20 compound treatment 1966670.0 143000.0 0.27 1308456.0 -55400.0 -0.11 0.1112 0.3835 3630156 CBKinase1_020120 CCCC1=C(C(c2cccnc2)n3ncnc3N1)C(=O)OCC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B21 compound treatment 1556411.0 -268000.0 -0.5 1270706.0 -93100.0 -0.19 -0.4868 -0.9088 3630157 CBKinase1_020121 COc1ccc(cc1)n2c(SCc3nc4ccccc4s3)nnc2c5cccnc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B22 compound treatment 2075919.0 252000.0 0.47 1478140.0 114000.0 0.23 0.496 0.9442 3630158 CBKinase1_020122 CCNC(=S)N1CCN(CC(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3)CC1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B23 compound treatment 820025.0 -1000000.0 -1.88 841444.0 -522000.0 -1.04 -2.071 -0.9612 3630159 CBKinase1_020123 CN(C(=O)CSc1nc2nc3CC(C)(C)OCc3cc2c(=O)n1c4ccc(C)cc4)c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 B24 compound treatment 1356588.0 -467000.0 -0.88 902969.0 -461000.0 -0.92 -1.2717 -0.9997 3630160 CBKinase1_020124 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)NC3CCCCC3)cc2)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C01 compound treatment 1524837.0 -299000.0 -0.56 999468.0 -364000.0 -0.73 -0.912 -0.9917 3630161 CBKinase1_020125 Cc1cc(nc(SCC(=O)Nc2ccc(OC(F)F)cc2)n1)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C02 compound treatment 1646332.0 -178000.0 -0.33 1094227.0 -270000.0 -0.54 -0.6168 -0.9734 3630162 CBKinase1_020126 CCOc1ccc(NC(=O)C2CC(=O)n3cnnc3N2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C03 compound treatment 1981051.0 157000.0 0.29 1182456.0 -181000.0 -0.36 -0.0478 -0.1023 3630163 CBKinase1_020127 O=c1oc2ccccc2cc1c3csc(Cc4nc5CCCCc5s4)n3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C04 compound treatment 1571691.0 -252000.0 -0.47 892352.0 -472000.0 -0.94 -1.0012 -0.9493 3630164 CBKinase1_020128 Clc1ccc(NC(=O)C2CC(=O)n3ncnc3N2)c(Cl)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C05 compound treatment 1623184.0 -201000.0 -0.38 1372522.0 8670.0 0.02 -0.2542 -0.6739 3630165 CBKinase1_020129 Cc1ccc(cc1)c2csc3nnc(SCC(=O)N4CCOCC4)n23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C06 compound treatment 1817824.0 -6110.0 -0.01 1229436.0 -134000.0 -0.27 -0.1981 -0.7366 3630166 CBKinase1_020130 COC(=O)c1ccccc1NC(=O)Cn2nnc(n2)c3ccc(SC)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C07 compound treatment 1317459.0 -506000.0 -0.95 1092901.0 -271000.0 -0.54 -1.0553 -0.9644 3630167 CBKinase1_020131 [O-][N+](=O)c1ccccc1N2CCN(CCCNC(=O)Nc3ccccc3F)CC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C08 compound treatment 1977251.0 153000.0 0.29 1241786.0 -122000.0 -0.24 0.031 0.0822 3630168 CBKinase1_020132 Cc1cccc(NC(=O)CSc2nncn2C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C09 compound treatment 1400553.0 -423000.0 -0.79 1314903.0 -49000.0 -0.1 -0.6312 -0.7882 3630169 CBKinase1_020133 COc1ccc(CCNc2nc(cs2)c3ccccn3)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C10 compound treatment 1030387.0 -794000.0 -1.49 1150322.0 -214000.0 -0.43 -1.3552 -0.8745 3630170 CBKinase1_020134 Clc1ccccc1NC(=O)Cn2cc(C(=O)C3CC3)c4ccccc24 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C11 mock treatment 1243152.0 -581000.0 -1.09 769884.0 -594000.0 -1.19 -1.6104 -0.9991 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C12 mock treatment 1514168.0 -310000.0 -0.58 1400515.0 36700.0 0.07 -0.3594 -0.6132 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C13 compound treatment 1394279.0 -430000.0 -0.81 1462204.0 98300.0 0.2 -0.4314 -0.5196 3630171 CBKinase1_020135 COc1ccc(OC)c(c1)n2c(CNC3CCN(Cc4ccccc4)CC3)nc5ccccc5c2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C14 compound treatment 1250473.0 -573000.0 -1.08 1307477.0 -56400.0 -0.11 -0.8409 -0.7769 3630172 CBKinase1_020136 COc1ccccc1NC(=O)CSc2ncnc3scc(c4ccccc4)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C15 mock treatment 1635111.0 -189000.0 -0.35 1007082.0 -357000.0 -0.71 -0.7549 -0.9479 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C16 mock treatment 1181857.0 -642000.0 -1.21 772541.0 -591000.0 -1.18 -1.688 -1.0 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C17 compound treatment 1499447.0 -324000.0 -0.61 1624794.0 261000.0 0.52 -0.062 -0.0773 3630173 CBKinase1_020137 Cc1ccccc1NC(=O)COc2ccc(cc2)c3nc4sc5CCCCc5c4c(=O)[nH]3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C18 compound treatment 1303831.0 -520000.0 -0.98 897471.0 -466000.0 -0.93 -1.3496 -0.9997 3630174 CBKinase1_020138 CC(=O)Nc1ccc(Br)cc1C(=O)OCc2cccc(c2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C19 compound treatment 1124265.0 -700000.0 -1.31 1030969.0 -333000.0 -0.67 -1.3993 -0.9503 3630175 CBKinase1_020139 COc1ccc(Cl)cc1NC(=S)NCc2ccco2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C20 compound treatment 1676270.0 -148000.0 -0.28 817178.0 -547000.0 -1.09 -0.9686 -0.8593 3630176 CBKinase1_020140 COc1ccccc1C(=O)N(Cc2nc(no2)c3ccc(Cl)cc3)C(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C21 compound treatment 1165652.0 -658000.0 -1.24 1411029.0 47200.0 0.09 -0.8072 -0.6513 3630177 CBKinase1_020141 COc1ccccc1n2c(SCC(=O)N)nc3ccc(I)cc3c2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C22 compound treatment 1037003.0 -787000.0 -1.48 924808.0 -439000.0 -0.88 -1.6651 -0.9691 3630178 CBKinase1_020142 COc1cccc(c1)S(=O)(=O)NCc2ccc(cc2)C(=O)Nc3ccc(Br)cc3F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C23 compound treatment 1394582.0 -429000.0 -0.81 739912.0 -624000.0 -1.25 -1.4518 -0.9777 3630179 CBKinase1_020143 OCc1cc(Br)ccc1OCC(=O)Nc2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 C24 compound treatment 1116544.0 -707000.0 -1.33 869919.0 -494000.0 -0.99 -1.6371 -0.9893 3630180 CBKinase1_020144 COc1ccccc1NC(=O)CSc2ncnc3sc(cc23)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D01 compound treatment 1526673.0 -297000.0 -0.56 1276874.0 -87000.0 -0.17 -0.5175 -0.8854 3630181 CBKinase1_020145 O=C(COc1ccc2c(cc(=O)oc2c1)c3ccccc3)Nc4sc5CCCc5c4C#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D02 compound treatment 1760912.0 -63000.0 -0.12 1202002.0 -162000.0 -0.32 -0.3124 -0.907 3630182 CBKinase1_020146 Fc1ccc(NC(=O)CSc2ncn(n2)c3ccccc3)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D03 compound treatment 1847302.0 23400.0 0.04 853077.0 -511000.0 -1.02 -0.6908 -0.6761 3630183 CBKinase1_020147 Nc1ncnc(Sc2nc3ccccc3s2)c1[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D04 compound treatment 1845909.0 22000.0 0.04 1089368.0 -274000.0 -0.55 -0.3588 -0.6521 3630184 CBKinase1_020148 COc1ccc(NC(=O)CSc2nc3ccccc3c(=O)[nH]2)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D05 compound treatment 2006700.0 183000.0 0.34 1078488.0 -285000.0 -0.57 -0.1607 -0.2414 3630185 CBKinase1_020149 CC(=O)Nc1ccccc1c2nc3ccccc3nc2OCC(=O)c4ccc(Br)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D06 compound treatment 1899261.0 75300.0 0.14 1863375.0 500000.0 1.0 0.806 0.7993 3630186 CBKinase1_020150 COc1ccc(cc1OC)C(=O)N(Cc2nc(no2)c3ccc(Cl)cc3)C(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D07 compound treatment 1904646.0 80700.0 0.15 1526825.0 163000.0 0.33 0.3375 0.9394 3630187 CBKinase1_020151 COc1ccc(CCNc2nc(cs2)c3ccc(NC(=O)C)cc3)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D08 compound treatment 1830874.0 6940.0 0.01 1217855.0 -146000.0 -0.29 -0.1971 -0.6748 3630188 CBKinase1_020152 CCn1c(SCC(=O)c2ccc(OC)cc2)nnc1c3ccccc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D09 compound treatment 1899192.0 75300.0 0.14 1551840.0 188000.0 0.38 0.3656 0.9108 3630189 CBKinase1_020153 CCOc1ccccc1NC(=O)CC2NC3CCCCC3NC2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D10 compound treatment 794397.0 -1030000.0 -1.93 683721.0 -680000.0 -1.36 -2.3279 -0.9852 3630190 CBKinase1_020154 Cc1cc(C)c(C)c(c1C)S(=O)(=O)NCc2ccc(cc2)C(=O)Nc3ccncc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D11 mock treatment 2032512.0 209000.0 0.39 1490326.0 126000.0 0.25 0.4556 0.9776 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D12 mock treatment 1823167.0 -762.0 0.0 1815455.0 452000.0 0.9 0.6372 0.706 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D13 compound treatment 2495373.0 671000.0 1.26 1357248.0 -6610.0 -0.01 0.882 0.6997 3630191 CBKinase1_020155 Cc1ccc(Cl)c(NC(=O)NCCN2CCN(CC2)c3ccccc3[N+](=O)[O-])c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D14 compound treatment 2124686.0 301000.0 0.56 994372.0 -369000.0 -0.74 -0.1229 -0.1322 3630192 CBKinase1_020156 COc1ccc(cc1[N+](=O)[O-])C(=O)N(Cc2nc(no2)c3ccccc3)C(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D15 mock treatment 2009119.0 185000.0 0.35 1306362.0 -57500.0 -0.11 0.1646 0.4495 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D16 mock treatment 2015001.0 191000.0 0.36 1436511.0 72700.0 0.15 0.3563 0.9208 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D17 compound treatment 1724467.0 -99500.0 -0.19 1617001.0 253000.0 0.51 0.2257 0.4186 3630193 CBKinase1_020157 COc1ccc(NC(=O)CSc2nnc3c4c5CCCc5sc4nc(c6ccccc6)n23)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D18 compound treatment 2192170.0 368000.0 0.69 1534914.0 171000.0 0.34 0.7306 0.9473 1974184 CBKinase1_020158 Cc1nc(SCC(=O)Nc2ccc3OCCOc3c2)c4c5CCCc5sc4n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D19 compound treatment 2096757.0 273000.0 0.51 1218452.0 -145000.0 -0.29 0.1567 0.2661 3630194 CBKinase1_020159 COc1ccc(cc1)c2nnc(SCC(=O)Nc3ccc(Br)c(Cl)c3)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D20 compound treatment 2191874.0 368000.0 0.69 1559174.0 195000.0 0.39 0.7645 0.9635 3630195 CBKinase1_020160 COC(=O)c1ccsc1NC(=O)CSc2nnnn2c3ccccc3SC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D21 compound treatment 2002261.0 178000.0 0.33 1273642.0 -90200.0 -0.18 0.1092 0.2873 3630196 CBKinase1_020161 COc1ccccc1NC(=O)CNS(=O)(=O)c2ccc(cc2)C(C)(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D22 compound treatment 1370223.0 -454000.0 -0.85 784036.0 -580000.0 -1.16 -1.4217 -0.9885 3630197 CBKinase1_020162 COc1ccc(NC(=O)c2ccco2)cc1NC(=O)CSc3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D23 compound treatment 1172498.0 -651000.0 -1.22 685144.0 -679000.0 -1.36 -1.824 -0.9987 3630198 CBKinase1_020163 COc1cc(ccc1OCC(=O)Nc2ccc(C)cc2)c3nc4ccccc4s3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 D24 compound treatment 1235121.0 -589000.0 -1.11 814024.0 -550000.0 -1.1 -1.5587 -1.0 3630199 CBKinase1_020164 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4cccnc4)C(=S)NCc5ccco5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E01 mock treatment 1371392.0 -453000.0 -0.85 1286987.0 -76900.0 -0.15 -0.7094 -0.8217 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E02 mock treatment 1395396.0 -429000.0 -0.8 1378678.0 14800.0 0.03 -0.5479 -0.6806 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E03 compound treatment 2050104.0 226000.0 0.42 1555557.0 192000.0 0.38 0.5712 0.9987 1722785 CBKinase1_020165 Nc1ncnc2n(CCc3ccccc3)c4nc5ccccc5nc4c12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E04 compound treatment 2039900.0 216000.0 0.41 1503085.0 139000.0 0.28 0.4835 0.9831 3630200 CBKinase1_020166 N#Cc1ccccc1CSc2nnc(c3ccco3)n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E05 compound treatment 2059750.0 236000.0 0.44 1544601.0 181000.0 0.36 0.5685 0.9949 3630201 CBKinase1_020167 Clc1ccc(cc1)c2csc(Cc3nc(cs3)c4cc5ccccc5oc4=O)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E06 compound treatment 1935737.0 112000.0 0.21 1457488.0 93600.0 0.19 0.2808 0.9984 3630202 CBKinase1_020168 COc1ccc(cc1)c2nnc(SCc3ccc(OC)c(c3)[N+](=O)[O-])[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E07 compound treatment 2117473.0 294000.0 0.55 1645793.0 282000.0 0.56 0.7881 0.9999 3630203 CBKinase1_020169 COC(=O)c1ccsc1NC(=O)CN2c3cccc4cccc(c34)S2(=O)=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E08 compound treatment 1871632.0 47700.0 0.09 1654631.0 291000.0 0.58 0.4743 0.8065 3630204 CBKinase1_020170 Cc1cc(nc(SCC(=O)Nc2ccc(SC(F)F)cc2)n1)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E09 mock treatment 1865734.0 41800.0 0.08 1638498.0 275000.0 0.55 0.4436 0.8001 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E10 mock treatment 2357602.0 534000.0 1.0 1380136.0 16300.0 0.03 0.7314 0.7297 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E11 compound treatment 2437890.0 614000.0 1.15 1703618.0 340000.0 0.68 1.2952 0.9682 3630205 CBKinase1_020171 OC(=O)CCNS(=O)(=O)c1cccc(F)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E12 compound treatment 2021251.0 197000.0 0.37 1800045.0 436000.0 0.87 0.8784 0.9273 3630206 CBKinase1_020172 COc1ccc(NC(=O)CC2NC(=O)NC2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E13 compound treatment 2134064.0 310000.0 0.58 1862550.0 499000.0 1.0 1.1165 0.9672 3630207 CBKinase1_020173 Cc1sc2ncnc(SCC(=O)NCC3CCCO3)c2c1c4ccc(Cl)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E14 compound treatment 1788401.0 -35500.0 -0.07 615472.0 -748000.0 -1.5 -1.1048 -0.7379 3630208 CBKinase1_020174 S=C(NCCc1c[nH]cn1)Nc2ccc(Oc3ccccc3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E15 compound treatment 2094163.0 270000.0 0.51 1611684.0 248000.0 0.5 0.709 0.9999 3630209 CBKinase1_020175 COC(=O)c1sc2ncn(CC(=O)Nc3ccccc3OC)c(=O)c2c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E16 compound treatment 1790758.0 -33200.0 -0.06 1447852.0 84000.0 0.17 0.0747 0.417 1196354 CBKinase1_020176 O=C(NCCN1CCOCC1)c2cccc(c2)S(=O)(=O)N3CCCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E17 mock treatment 2031424.0 207000.0 0.39 1835382.0 472000.0 0.94 0.9418 0.9236 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E18 mock treatment 2018010.0 194000.0 0.36 1591332.0 227000.0 0.45 0.5791 0.994 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E19 compound treatment 1805504.0 -18400.0 -0.03 1545089.0 181000.0 0.36 0.2317 0.6367 3630210 CBKinase1_020177 Cc1nc(CSc2nnc3scc(c4ccc(C)cc4)n23)cs1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E20 compound treatment 1795776.0 -28200.0 -0.05 1475410.0 112000.0 0.22 0.1203 0.5249 3630211 CBKinase1_020178 Cc1ccc(cc1S(=O)(=O)N2CCC(CC2)C(=O)O)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E21 compound treatment 1838748.0 14800.0 0.03 1428075.0 64200.0 0.13 0.1104 0.8408 3630212 CBKinase1_020179 Oc1ccnc(SCC(=O)Nc2cccc(c2)C(F)(F)F)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E22 compound treatment 2164695.0 341000.0 0.64 1297225.0 -66600.0 -0.13 0.3582 0.5482 3630213 CBKinase1_020180 Cc1cc(C)nc(NC2=NC(=O)CC(N2c3cccc(c3)C(F)(F)F)C(=O)O)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E23 compound treatment 1682089.0 -142000.0 -0.27 1404143.0 40300.0 0.08 -0.1314 -0.4722 3630214 CBKinase1_020181 CN(CC(=O)Nc1cc(ccc1C)[N+](=O)[O-])S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 E24 compound treatment 1140352.0 -684000.0 -1.28 801323.0 -563000.0 -1.12 -1.7025 -0.9978 3630215 CBKinase1_020182 Clc1ccc(cc1)n2c(SCc3nc4ccccc4s3)nnc2c5cccs5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F01 mock treatment 1671180.0 -153000.0 -0.29 1272651.0 -91200.0 -0.18 -0.3317 -0.9761 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F02 mock treatment 1603606.0 -220000.0 -0.41 1259048.0 -105000.0 -0.21 -0.4406 -0.9503 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F03 compound treatment 1822599.0 -1330.0 0.0 1410579.0 46700.0 0.09 0.0643 0.6879 3630216 CBKinase1_020183 Cc1cc(Br)cc(C)c1NC(=O)CSc2nnc(c3cc4cc(Cl)ccc4o3)n2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F04 compound treatment 1509811.0 -314000.0 -0.59 1145348.0 -219000.0 -0.44 -0.7258 -0.9891 3630217 CBKinase1_020184 Fc1ccc(NC(=O)N(Cc2ccco2)C3CC(=O)N(C3=O)c4ccc(F)cc4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F05 compound treatment 1920684.0 96800.0 0.18 1138518.0 -225000.0 -0.45 -0.19 -0.3913 3630218 CBKinase1_020185 CCC1(C)Cc2c(CO1)sc3nnn(CC(=O)N(c4ccccc4)c5ccccc5)c(=O)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F06 compound treatment 2346322.0 522000.0 0.98 1608974.0 245000.0 0.49 1.0399 0.9486 3630219 CBKinase1_020186 COc1cccc(c1)S(=O)(=O)NCc2ccc(cc2)C(=O)Nc3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F07 compound treatment 2369679.0 546000.0 1.02 1691140.0 327000.0 0.65 1.187 0.9765 3630220 CBKinase1_020187 Cn1c(SCC(=O)NC2CCCCCC2)nnc1c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F08 compound treatment 2350895.0 527000.0 0.99 1412393.0 48500.0 0.1 0.7681 0.7727 3630221 CBKinase1_020188 Cc1sc2ncnc(SCC(=O)N3CCOCC3)c2c1c4ccc(Cl)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F09 mock treatment 2506804.0 683000.0 1.28 1633424.0 270000.0 0.54 1.2875 0.9258 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F10 mock treatment 2169548.0 346000.0 0.65 1520782.0 157000.0 0.31 0.6806 0.9444 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F11 compound treatment 1821186.0 -2740.0 -0.01 1426646.0 62800.0 0.13 0.0851 0.6775 3630222 CBKinase1_020189 Cn1c(SCc2nc(no2)c3ccccc3)nnc1c4ccco4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F12 compound treatment 2264949.0 441000.0 0.83 1292283.0 -71600.0 -0.14 0.4843 0.5764 3630223 CBKinase1_020190 CC(C)C(NS(=O)(=O)c1ccc(Oc2ccccc2Cl)cc1)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F13 compound treatment 2499191.0 675000.0 1.27 1978206.0 614000.0 1.23 1.7646 0.9999 3630224 CBKinase1_020191 COC(=O)c1ccc(cc1)N2C(=O)CC(SCC(=O)Nc3ccc(Br)cc3)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F14 compound treatment 2372878.0 549000.0 1.03 1581086.0 217000.0 0.43 1.0357 0.9262 3630225 CBKinase1_020192 O=C(CC1N(Cc2cccs2)C(=O)N(C1=O)c3ccccc3)Nc4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F15 compound treatment 2293803.0 470000.0 0.88 1606343.0 242000.0 0.48 0.9665 0.9602 3630226 CBKinase1_020193 CC(=O)OCCCNC(=O)c1cc2ccccc2oc1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F16 compound treatment 2145934.0 322000.0 0.6 1503551.0 140000.0 0.28 0.6249 0.9384 3630227 CBKinase1_020194 COc1ccc(Cl)cc1NC(=S)NCCc2c[nH]c3ccccc23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F17 mock treatment 2005023.0 181000.0 0.34 1517598.0 154000.0 0.31 0.4577 0.9987 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F18 mock treatment 2255469.0 432000.0 0.81 1708552.0 345000.0 0.69 1.06 0.9967 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F19 compound treatment 1973900.0 150000.0 0.28 1417391.0 53500.0 0.11 0.2747 0.9122 3119007 CBKinase1_020195 Cc1ccc(C)c(c1)S(=O)(=O)NCC(=O)Nc2nsc(n2)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F20 compound treatment 2149628.0 326000.0 0.61 1420927.0 57100.0 0.11 0.513 0.8248 3630228 CBKinase1_020196 CCc1ccc(CCC(=O)Nc2ccc(OC)cc2)o1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F21 compound treatment 2145513.0 322000.0 0.6 1630834.0 267000.0 0.53 0.8042 0.9981 3630229 CBKinase1_020197 Cn1c(SCC(=O)c2ccc(Br)cc2)nnc1c3cc4ccccc4o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F22 compound treatment 1952195.0 128000.0 0.24 1154543.0 -209000.0 -0.42 -0.1255 -0.2601 3630230 CBKinase1_020198 CC1(C)Cc2c(CS1)sc3nc(SCC(=O)Nc4ccc(Br)cc4)nc(N)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F23 compound treatment 1854565.0 30600.0 0.06 1238560.0 -125000.0 -0.25 -0.1364 -0.5309 3630231 CBKinase1_020199 NC(=O)CSc1nc(nc2sc3CCCCc3c12)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 F24 compound treatment 1178063.0 -646000.0 -1.21 714710.0 -649000.0 -1.3 -1.7748 -0.9994 3630232 CBKinase1_020200 Clc1ccc(NC(=O)CC2NC3CCCCC3NC2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G01 compound treatment 1730469.0 -93500.0 -0.18 1192617.0 -171000.0 -0.34 -0.3661 -0.9518 3630233 CBKinase1_020201 Fc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3cc(Cl)cc(Cl)c3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G02 compound treatment 1675056.0 -149000.0 -0.28 1362882.0 -973.0 0.0 -0.199 -0.712 3630234 CBKinase1_020202 [O-][N+](=O)c1cc(ccc1NCCCNC(=O)c2ccc(F)cc2)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G03 mock treatment 1764580.0 -59300.0 -0.11 1290713.0 -73100.0 -0.15 -0.1822 -0.991 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G04 mock treatment 1916326.0 92400.0 0.17 1460201.0 96300.0 0.19 0.2588 0.9986 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G05 compound treatment 2474386.0 650000.0 1.22 1593628.0 230000.0 0.46 1.1882 0.9108 3630235 CBKinase1_020203 CNC(=O)CN(C#N)c1nc(nc(n1)N(C)C)N(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G06 compound treatment 2207386.0 383000.0 0.72 1794564.0 431000.0 0.86 1.1177 0.996 3630236 CBKinase1_020204 Cc1ccn2cc(nc2c1)c3cccc(NS(=O)(=O)c4cc(ccc4C)[N+](=O)[O-])c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G07 compound treatment 2405500.0 582000.0 1.09 1594584.0 231000.0 0.46 1.0981 0.9265 3630237 CBKinase1_020205 Fc1ccc(NC(=O)C2CC(=O)n3cnnc3N2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G08 compound treatment 2457943.0 634000.0 1.19 1896077.0 532000.0 1.06 1.5938 0.9984 3630238 CBKinase1_020206 COc1ccc(cc1)n2c(SCC(=O)N)nnc2c3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G09 compound treatment 2453948.0 630000.0 1.18 1878617.0 515000.0 1.03 1.5638 0.9976 3630239 CBKinase1_020207 CCOC(=O)c1c(NC(=O)CN2C(=O)c3ccccc3C2=O)sc(C)c1c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G10 compound treatment 2387741.0 564000.0 1.06 1664638.0 301000.0 0.6 1.1735 0.9641 3630240 CBKinase1_020208 COc1ccc(CCNc2ncnc3scc(c4cccs4)c23)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G11 compound treatment 2678892.0 855000.0 1.61 1775070.0 411000.0 0.82 1.7161 0.9517 3630241 CBKinase1_020209 CCc1nc(SCC(=O)OC)c2c3CCCCc3sc2n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G12 compound treatment 2382600.0 559000.0 1.05 1761977.0 398000.0 0.8 1.3043 0.9907 3630242 CBKinase1_020210 COc1ccc(NC(=O)C2CC(=O)n3c(N2)nc4ccccc34)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G13 compound treatment 2511134.0 687000.0 1.29 1975306.0 611000.0 1.22 1.7764 0.9996 3630243 CBKinase1_020211 Cc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccc(I)cc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G14 compound treatment 2421880.0 598000.0 1.12 1592526.0 229000.0 0.46 1.1169 0.9215 3630244 CBKinase1_020212 CCOc1ccc(cc1)c2nnc(SCc3ccc(o3)C(=O)OC)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G15 compound treatment 2309717.0 486000.0 0.91 1529478.0 166000.0 0.33 0.8789 0.9059 3630245 CBKinase1_020213 CC(C)N(C(=O)CSc1nc2cc(Cl)ccc2[nH]1)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G16 compound treatment 2158970.0 335000.0 0.63 1776606.0 413000.0 0.82 1.0281 0.991 3630246 CBKinase1_020214 COc1ccc(Cl)cc1NC(=O)CC2NC3CCCCC3NC2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G17 compound treatment 2523549.0 700000.0 1.31 1537352.0 173000.0 0.35 1.1739 0.8642 3630247 CBKinase1_020215 CCc1ccc(CCC(=O)Nc2ccc(cc2)C(=O)O)o1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G18 compound treatment 2122662.0 299000.0 0.56 1594847.0 231000.0 0.46 0.723 0.9953 3630248 CBKinase1_020216 COc1ccc(CCNc2nc(cs2)c3ccc(O)cc3)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G19 mock treatment 2087456.0 264000.0 0.49 1693766.0 330000.0 0.66 0.8161 0.99 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G20 mock treatment 1996902.0 173000.0 0.32 1476494.0 113000.0 0.23 0.3888 0.984 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G21 compound treatment 2038298.0 214000.0 0.4 1626708.0 263000.0 0.53 0.6561 0.9913 1441249 CBKinase1_020217 S=C(NCC1CCCO1)NCc2ccco2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G22 compound treatment 2156777.0 333000.0 0.62 1651010.0 287000.0 0.57 0.8477 0.9991 3630249 CBKinase1_020218 Cc1ccccc1NC(=O)CSC2CC(=O)N(C2=O)c3ccc(F)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G23 compound treatment 1971292.0 147000.0 0.28 1437413.0 73600.0 0.15 0.2996 0.9562 3630250 CBKinase1_020219 Clc1ccc(Cl)c(NC(=O)c2ccc(OCC(=O)Nc3sc4CCCc4c3C#N)cc2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 G24 compound treatment 1398511.0 -425000.0 -0.8 1122156.0 -242000.0 -0.48 -0.9063 -0.971 1392885 CBKinase1_020220 Cc1ccc(cc1S(=O)(=O)N2CCCCC2)C(=O)NCCN3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H01 compound treatment 1779162.0 -44800.0 -0.08 1108368.0 -255000.0 -0.51 -0.4205 -0.8126 3630251 CBKinase1_020221 O=C(CC1NC(=O)NC1=O)Nc2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H02 compound treatment 1959904.0 136000.0 0.26 1306331.0 -57500.0 -0.11 0.0992 0.3543 3630252 CBKinase1_020222 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2cc(C)ccc2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H03 mock treatment 2078900.0 255000.0 0.48 1367690.0 3830.0 0.01 0.3439 0.7183 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H04 mock treatment 2143199.0 319000.0 0.6 1436085.0 72200.0 0.14 0.5259 0.853 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H05 compound treatment 2157850.0 334000.0 0.63 1609113.0 245000.0 0.49 0.7899 0.9926 3630253 CBKinase1_020223 CCN(CC)CCNc1ncnc(N)c1[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H06 compound treatment 2345829.0 522000.0 0.98 1480185.0 116000.0 0.23 0.8572 0.8513 3630254 CBKinase1_020224 CC(=O)c1ccc(NC(=O)CSc2nnc3n(C)c(=O)c4c5CCCCc5sc4n23)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H07 compound treatment 2478537.0 655000.0 1.23 1565933.0 202000.0 0.4 1.1546 0.8925 3630255 CBKinase1_020225 COc1cccc(c1)S(=O)(=O)N2CCCC2C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H08 compound treatment 2396211.0 572000.0 1.07 1784055.0 420000.0 0.84 1.3536 0.9926 3630256 CBKinase1_020226 CC1(C)Cc2c(CS1)sc3nc(SCC(=O)c4ccccc4)nc(N)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H09 compound treatment 2605603.0 782000.0 1.47 1594331.0 230000.0 0.46 1.3634 0.8864 3630257 CBKinase1_020227 COc1ccc(NC(=O)CSc2nnc(c3ccco3)n2c4ccccc4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H10 compound treatment 2349010.0 525000.0 0.99 1548599.0 185000.0 0.37 0.9581 0.9102 3630258 CBKinase1_020228 OC(=O)CSc1nnc2n(CCc3ccccc3)c(=O)c4c5CCCCc5sc4n12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H11 compound treatment 2353224.0 529000.0 0.99 1681545.0 318000.0 0.63 1.1516 0.9766 3630259 CBKinase1_020229 CCCOc1ccc(Oc2nc(NC)nc(n2)N3CCOCC3)nn1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H12 compound treatment 2541963.0 718000.0 1.35 1709823.0 346000.0 0.69 1.4421 0.9519 3630260 CBKinase1_020230 CCCc1cc(=O)[nH]c(Nc2nc(C)c3ccc(OC)cc3n2)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H13 compound treatment 2310778.0 487000.0 0.91 1485194.0 121000.0 0.24 0.8178 0.8648 3630261 CBKinase1_020231 COc1ccc(cc1OC)C(=O)N(Cc2nc(no2)c3ccccc3)C(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H14 compound treatment 2165328.0 341000.0 0.64 1847524.0 484000.0 0.97 1.1368 0.9801 3630262 CBKinase1_020232 Cc1sc2nc(SCC(=O)N3CCC(CC3)c4noc5ccc(F)cc45)n(c6ccccc6)c(=O)c2c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H15 compound treatment 862084.0 -962000.0 -1.81 562162.0 -802000.0 -1.6 -2.4099 -0.9982 3630263 CBKinase1_020233 CC1(C)Cc2nc(nc(SCC(=O)Nc3cccc(c3)C(F)(F)F)c2CO1)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H16 compound treatment 2273563.0 450000.0 0.84 1520625.0 157000.0 0.31 0.8184 0.909 1207434 CBKinase1_020234 Cc1ccc(cc1S(=O)(=O)N(CCO)CCO)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H17 compound treatment 2356273.0 532000.0 1.0 1833720.0 470000.0 0.94 1.3707 0.9995 3630264 CBKinase1_020235 CC(Oc1ccc(Cl)cc1Cl)C(=O)NC(=S)Nc2cccc(NC(=O)c3cccs3)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H18 compound treatment 2251125.0 427000.0 0.8 1758457.0 395000.0 0.79 1.1248 1.0 3630265 CBKinase1_020236 CC(C)N(Cc1nc(no1)c2ccccc2)C(=O)c3ccc(cc3)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H19 mock treatment 2485229.0 661000.0 1.24 1492841.0 129000.0 0.26 1.0602 0.8361 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H20 mock treatment 2304585.0 481000.0 0.9 1576467.0 213000.0 0.42 0.9385 0.941 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H21 compound treatment 2147940.0 324000.0 0.61 1351434.0 -12400.0 -0.02 0.4126 0.6777 3630266 CBKinase1_020237 OC(=O)Cn1cc(C(=O)c2ccccc2)c3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H22 compound treatment 2034001.0 210000.0 0.39 1465962.0 102000.0 0.2 0.4232 0.953 3630267 CBKinase1_020238 NC(=O)CSc1nnc(s1)c2cccnc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H23 compound treatment 1839940.0 16000.0 0.03 1023364.0 -340000.0 -0.68 -0.46 -0.6752 3630268 CBKinase1_020239 Clc1ccc(NC(=O)Cn2cc(C(=O)c3ccccc3)c4ccccc24)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 H24 compound treatment 1499176.0 -325000.0 -0.61 622070.0 -742000.0 -1.48 -1.4795 -0.9229 3630269 CBKinase1_020240 CCc1c(C)nc(Nc2nc(C)c3ccc(OC)cc3n2)[nH]c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I01 compound treatment 1520286.0 -304000.0 -0.57 1157573.0 -206000.0 -0.41 -0.6946 -0.9874 3630270 CBKinase1_020241 COc1cccc(CNc2nc3ccccc3n2CCN4CCOCC4)c1O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I02 compound treatment 1734110.0 -89800.0 -0.17 1129155.0 -235000.0 -0.47 -0.4509 -0.9046 1394944 CBKinase1_020242 C=CCn1c(SCc2nc3ccccc3[nH]2)nnc1c4ccco4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I03 compound treatment 1762161.0 -61800.0 -0.12 1408100.0 44200.0 0.09 -0.0195 -0.1335 3630271 CBKinase1_020243 COc1ccc(cc1)c2nnc(SCc3cc(Cl)ccc3OC)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I04 compound treatment 1814659.0 -9270.0 -0.02 1398909.0 35100.0 0.07 0.0372 0.5158 3630272 CBKinase1_020244 COc1ccc(cc1)c2nnc(SCC(=O)Nc3c(F)cc(F)cc3Br)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I05 mock treatment 2119794.0 296000.0 0.56 1493060.0 129000.0 0.26 0.5754 0.9393 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I06 mock treatment 1715337.0 -109000.0 -0.2 1367812.0 3960.0 0.01 -0.1386 -0.6792 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I07 compound treatment 2055538.0 232000.0 0.43 1314121.0 -49700.0 -0.1 0.2372 0.5317 3630273 CBKinase1_020245 COc1cccc(NC(=O)CSc2nncn2C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I08 compound treatment 1933351.0 109000.0 0.21 1523024.0 159000.0 0.32 0.3702 0.9776 3630274 CBKinase1_020246 Nc1nnc(SCC(=O)Nc2ccccc2Br)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I09 compound treatment 2082762.0 259000.0 0.49 1300551.0 -63300.0 -0.13 0.2541 0.5061 3630275 CBKinase1_020247 Cc1ccc(cc1)c2nnc(SCC(=O)Nc3cc(C)c(C)cc3Br)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I10 compound treatment 1883471.0 59500.0 0.11 1347836.0 -16000.0 -0.03 0.0564 0.4851 3630276 CBKinase1_020248 CCOC(=O)c1ccc(NC(=O)CC2NC3CCCCC3NC2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I11 compound treatment 2249624.0 426000.0 0.8 1372403.0 8550.0 0.02 0.5772 0.7221 3630277 CBKinase1_020249 Cc1cc(C(=O)CSc2nc[nH]n2)c(C)n1c3cccc(c3)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I12 compound treatment 2356359.0 532000.0 1.0 1654037.0 290000.0 0.58 1.1169 0.9665 3630278 CBKinase1_020250 FC(F)(F)c1cccc(NC(=O)CN2C(=O)CNC2=O)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I13 compound treatment 2053782.0 230000.0 0.43 1442723.0 78900.0 0.16 0.4166 0.9068 3630279 CBKinase1_020251 Nc1ncnc(NCCCN2CCOCC2)c1[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I14 compound treatment 1894642.0 70700.0 0.13 1466105.0 102000.0 0.2 0.2384 0.9782 3630280 CBKinase1_020252 CC(Sc1nc(N)c2c3CC(C)(C)OCc3sc2n1)C(=O)Nc4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I15 compound treatment 2389071.0 565000.0 1.06 1665855.0 302000.0 0.6 1.177 0.9643 3630281 CBKinase1_020253 Fc1ccc(NC(=O)Cn2cc(C(=O)c3ccccc3)c4ccccc24)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I16 compound treatment 2103925.0 280000.0 0.53 1428260.0 64400.0 0.13 0.4627 0.855 3630282 CBKinase1_020254 COc1ccc(c(OC)c1)S(=O)(=O)n2cc(c(N)n2)c3ccc(F)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I17 compound treatment 2029174.0 205000.0 0.39 1420798.0 56900.0 0.11 0.3529 0.8784 3630283 CBKinase1_020255 Cc1ccccc1NC(=O)CSC2CC(=O)N(C2=O)c3cc(Cl)cc(Cl)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I18 compound treatment 1269776.0 -554000.0 -1.04 729690.0 -634000.0 -1.27 -1.6319 -0.9952 3630284 CBKinase1_020256 COc1ccc(cc1CSc2nnc(c3ccc(Br)cc3)n2c4ccccc4)C(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I19 compound treatment 2214223.0 390000.0 0.73 1263265.0 -101000.0 -0.2 0.3759 0.4948 3630285 CBKinase1_020257 O=C(CSc1nnnn1c2ccccc2)Nc3ccc(cc3)c4nc5ccccc5s4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I20 compound treatment 2071020.0 247000.0 0.46 1653499.0 290000.0 0.58 0.7374 0.994 3630286 CBKinase1_020258 O=C(CSc1nnc(c2ccco2)n1c3ccccc3)N4CCOCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I21 mock treatment 2072134.0 248000.0 0.47 1482221.0 118000.0 0.24 0.4968 0.9506 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I22 mock treatment 2148522.0 325000.0 0.61 1527409.0 164000.0 0.33 0.662 0.9574 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I23 compound treatment 1884521.0 60600.0 0.11 1634634.0 271000.0 0.54 0.4631 0.8374 1784349 CBKinase1_020259 COc1ccc(cc1OC)C2(CNC(=O)c3ccc(OC)c(c3)[N+](=O)[O-])CCCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 I24 compound treatment 1423715.0 -400000.0 -0.75 989601.0 -374000.0 -0.75 -1.0602 -1.0 3630287 CBKinase1_020260 COc1ccc(Oc2c(oc3cc(OCC(=O)Nc4ccccc4F)ccc3c2=O)C(F)(F)F)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J01 compound treatment 1030397.0 -794000.0 -1.49 1039444.0 -324000.0 -0.65 -1.5119 -0.9306 3630288 CBKinase1_020261 Cc1cccc(NC(=O)c2cc(NC(=O)C3CCCCC3C(=O)O)ccc2N4CCCCC4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J02 compound treatment 1655258.0 -169000.0 -0.32 977460.0 -386000.0 -0.77 -0.77 -0.9225 3630289 CBKinase1_020262 Cn1c(SCC(=O)N2CCc3ccccc23)nnc1c4ccc(NC(=O)c5ccccc5Br)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J03 compound treatment 1376884.0 -447000.0 -0.84 971463.0 -392000.0 -0.78 -1.148 -0.9994 3630290 CBKinase1_020263 COc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccccc3C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J04 compound treatment 1828930.0 5000.0 0.01 1275540.0 -88300.0 -0.18 -0.1182 -0.6686 3630291 CBKinase1_020264 Cc1sc(NC(=O)COc2c(C)cc(Br)cc2C)c(C(=O)N)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J05 mock treatment 1848232.0 24300.0 0.05 1102404.0 -261000.0 -0.52 -0.3372 -0.6429 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J06 mock treatment 1650931.0 -173000.0 -0.32 1129244.0 -235000.0 -0.47 -0.5612 -0.9839 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J07 compound treatment 1988296.0 164000.0 0.31 1063058.0 -301000.0 -0.6 -0.2069 -0.3062 3630292 CBKinase1_020265 CC1(C)Cc2nc3sc4c(=O)n(CC(=O)NCCc5ccccc5)cnc4c3cc2CO1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J08 compound treatment 2031181.0 207000.0 0.39 1148057.0 -216000.0 -0.43 -0.0299 -0.0514 3630293 CBKinase1_020266 O=C(CSc1nnnn1c2ccccc2)Nc3nsc(n3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J09 compound treatment 2145539.0 322000.0 0.6 1354146.0 -9710.0 -0.02 0.4132 0.684 3630294 CBKinase1_020267 Cc1ccc(NC(=O)CSc2nnc(c3ccco3)n2c4ccccc4)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J10 compound treatment 2089602.0 266000.0 0.5 1354079.0 -9780.0 -0.02 0.3389 0.6789 3630295 CBKinase1_020268 Cn1nnnc1SCC(=O)Nc2cc(Cl)cc(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J11 compound treatment 2182227.0 358000.0 0.67 1459392.0 95500.0 0.19 0.6107 0.8733 3630296 CBKinase1_020269 CCc1ccc(NC(=O)CC2NCCNC2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J12 compound treatment 1879638.0 55700.0 0.1 1195877.0 -168000.0 -0.34 -0.1634 -0.4648 3630297 CBKinase1_020270 Cc1cc(C(=O)CSc2nnnn2c3ccccc3)c(C)n1c4cc(F)ccc4F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J13 compound treatment 2177521.0 354000.0 0.66 1468763.0 105000.0 0.21 0.6177 0.8872 3630298 CBKinase1_020271 COc1cccc(c1)S(=O)(=O)NCC(=O)N2CCCCCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J14 compound treatment 1849442.0 25500.0 0.05 1161725.0 -202000.0 -0.4 -0.2518 -0.6189 3630299 CBKinase1_020272 NC(=O)c1cc(sc1NC(=O)Cn2cnc3scc(c4ccccc4)c3c2=O)c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J15 compound treatment 1955947.0 132000.0 0.25 1379081.0 15200.0 0.03 0.1968 0.788 3630300 CBKinase1_020273 COc1ccc(NC(=O)CSc2nc3ccccc3[nH]2)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J16 compound treatment 2055781.0 232000.0 0.44 1466630.0 103000.0 0.21 0.453 0.9413 3630301 CBKinase1_020274 Cc1nc2ccccc2n1CC(=O)NCCN3CCCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J17 compound treatment 2190446.0 367000.0 0.69 1363019.0 -836.0 0.0 0.4854 0.7054 3630302 CBKinase1_020275 Cc1sc2ncnc(SCC(=O)N3CCC(CC3)c4noc5ccc(F)cc45)c2c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J18 compound treatment 1831324.0 7390.0 0.01 1753657.0 390000.0 0.78 0.5607 0.7196 3630303 CBKinase1_020276 Fc1ccc2onc(C3CCN(CC3)C(=O)CSc4nc5sc6CCCc6c5c(=O)n4c7ccccc7)c2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J19 compound treatment 1915840.0 91900.0 0.17 1143227.0 -221000.0 -0.44 -0.1898 -0.4008 3630304 CBKinase1_020277 O=C(CSc1ncn(n1)c2ccccc2)Nc3ccc4OCCOc4c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J20 compound treatment 1451810.0 -372000.0 -0.7 963747.0 -400000.0 -0.8 -1.0594 -0.9977 3630305 CBKinase1_020278 Cc1cc(nc(SCC(=O)Nc2cccc(c2)C(F)(F)F)n1)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J21 mock treatment 1804554.0 -19400.0 -0.04 1166109.0 -198000.0 -0.4 -0.3052 -0.7689 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J22 mock treatment 1920372.0 96400.0 0.18 1195041.0 -169000.0 -0.34 -0.1106 -0.2887 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J23 compound treatment 1837379.0 13400.0 0.03 936202.0 -428000.0 -0.85 -0.5865 -0.6859 3630306 CBKinase1_020279 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2ccc(I)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 J24 compound treatment 1637897.0 -186000.0 -0.35 749689.0 -614000.0 -1.23 -1.1149 -0.8736 3630307 CBKinase1_020280 [O-][N+](=O)c1cccc(c1)c2csc3ncn(CC(=O)Nc4ccc(F)c(Cl)c4)c(=O)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K01 compound treatment 1157535.0 -666000.0 -1.25 1236654.0 -127000.0 -0.25 -1.0644 -0.8338 3630308 CBKinase1_020281 Cc1nc(CSc2nc3sc(C)c(C)c3c(=O)n2CC=C)cs1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K02 compound treatment 1492715.0 -331000.0 -0.62 1124940.0 -239000.0 -0.48 -0.7773 -0.9915 3630309 CBKinase1_020282 Cc1sc2nc(SCc3n[nH]c(=S)n3c4ccccc4)[nH]c(=O)c2c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K03 compound treatment 1283165.0 -541000.0 -1.02 1071375.0 -292000.0 -0.58 -1.1312 -0.9656 3630310 CBKinase1_020283 CC(=O)c1ccc(OC(=O)CCCN2C(=O)c3ccccc3C2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K04 compound treatment 1266137.0 -558000.0 -1.05 1242702.0 -121000.0 -0.24 -0.9117 -0.8482 3630311 CBKinase1_020284 [O-][N+](=O)c1ccc2nc(SCC(=O)Nc3cc(Cl)cc(Cl)c3)sc2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K05 compound treatment 1652272.0 -172000.0 -0.32 1298867.0 -65000.0 -0.13 -0.3197 -0.9202 3630312 CBKinase1_020285 COc1ccc(NC(=O)c2ccco2)cc1NC(=O)c3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K06 compound treatment 1168653.0 -655000.0 -1.23 1550806.0 187000.0 0.37 -0.6057 -0.4711 3630313 CBKinase1_020286 O=S(=O)(CCSc1ccccn1)c2nc3ccccc3s2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K07 mock treatment 1569192.0 -255000.0 -0.48 1486190.0 122000.0 0.24 -0.1653 -0.3077 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K08 mock treatment 1858445.0 34500.0 0.06 1208368.0 -155000.0 -0.31 -0.1739 -0.5479 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K09 compound treatment 1851349.0 27400.0 0.05 1504082.0 140000.0 0.28 0.2346 0.8232 3630314 CBKinase1_020287 CSc1ccccc1NC(=O)CN(C)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K10 compound treatment 1496756.0 -327000.0 -0.61 1495382.0 132000.0 0.26 -0.2484 -0.3718 3630315 CBKinase1_020288 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2ccc(cc2)C(=O)N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K11 compound treatment 2028206.0 204000.0 0.38 1445775.0 81900.0 0.16 0.3869 0.928 3630316 CBKinase1_020289 O=C(NCc1ccco1)c2ccc3nc(c4ccco4)c(nc3c2)c5ccco5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K12 compound treatment 1569403.0 -255000.0 -0.48 1757046.0 393000.0 0.79 0.2178 0.2368 3630317 CBKinase1_020290 CC(C)(C)NC(=O)CSc1nnc(c2ccco2)n1c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K13 compound treatment 1770962.0 -53000.0 -0.1 1855345.0 491000.0 0.98 0.6243 0.6323 3630318 CBKinase1_020291 Cc1nc(SCC(=O)NCc2ccco2)c3c4CCCc4sc3n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K14 compound treatment 1795505.0 -28400.0 -0.05 1582499.0 219000.0 0.44 0.2713 0.6162 3630319 CBKinase1_020292 CC1(C)Cc2c(CS1)sc3nc(SCC(=O)c4ccc(Cl)cc4)nc(N)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K15 mock treatment 1827337.0 3410.0 0.01 1436075.0 72200.0 0.14 0.1066 0.7377 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K16 mock treatment 1820743.0 -3190.0 -0.01 1569330.0 205000.0 0.41 0.2862 0.6967 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K17 compound treatment 1884491.0 60600.0 0.11 1442749.0 78900.0 0.16 0.1919 0.9871 3630320 CBKinase1_020293 CN1CCN(CC(=O)Nc2ccccc2[N+](=O)[O-])CC1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K18 compound treatment 1547624.0 -276000.0 -0.52 1430873.0 67000.0 0.13 -0.2721 -0.5079 3630321 CBKinase1_020294 CC1CCc2c(C1)sc3ncnc(SCC(=O)Nc4ccc5OCCOc5c4)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K19 compound treatment 1607192.0 -217000.0 -0.41 1462430.0 98600.0 0.2 -0.1484 -0.3283 3630322 CBKinase1_020295 COC(=O)c1cc(OC)c(OC)cc1NC(=O)CN2CCOCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K20 compound treatment 388044.0 -1440000.0 -2.7 400610.0 -963000.0 -1.93 -3.2674 -0.9864 3630323 CBKinase1_020296 Nc1ncnc(Oc2cccc3cccnc23)c1[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K21 compound treatment 1241354.0 -583000.0 -1.09 1087918.0 -276000.0 -0.55 -1.1633 -0.9498 3630324 CBKinase1_020297 Cc1cccc(Nc2ncnc(N)c2[N+](=O)[O-])n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K22 compound treatment 1780737.0 -43200.0 -0.08 1518027.0 154000.0 0.31 0.1606 0.5039 3630325 CBKinase1_020298 Cn1c(SCC(=O)Nc2cccc(c2)C(F)(F)F)nnc1c3cc4cc(Cl)ccc4o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K23 mock treatment 1800201.0 -23700.0 -0.04 1285032.0 -78800.0 -0.16 -0.1429 -0.8728 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 K24 mock treatment 1436497.0 -387000.0 -0.73 691654.0 -672000.0 -1.34 -1.4643 -0.9585 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L01 compound treatment 938971.0 -885000.0 -1.66 955712.0 -408000.0 -0.82 -1.7516 -0.9464 3630326 CBKinase1_020299 CCCOc1ccc(cc1)c2nnc(SCC(=O)N)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L02 compound treatment 1119499.0 -704000.0 -1.32 1063908.0 -300000.0 -0.6 -1.359 -0.936 3630327 CBKinase1_020300 Cn1c(CN2CCOCC2)nnc1SCC(=O)Nc3ccc4OCCOc4c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L03 compound treatment 1364763.0 -459000.0 -0.86 1011850.0 -352000.0 -0.7 -1.107 -0.9949 3630328 CBKinase1_020301 Cc1nn(c(O)c1C2OC(=O)c3ccccc23)c4nc5ccccc5[nH]4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L04 compound treatment 1033888.0 -790000.0 -1.48 936770.0 -427000.0 -0.85 -1.6524 -0.9656 1283719 CBKinase1_020302 Nc1nnc(SCC(=O)Nc2cc(Cl)cc(Cl)c2)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L05 compound treatment 1330795.0 -493000.0 -0.93 1012911.0 -351000.0 -0.7 -1.1506 -0.9906 3630329 CBKinase1_020303 CCN(CC)c1nc(Nc2ccccc2)nc(Oc3ccc(O)nn3)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L06 compound treatment 1451255.0 -373000.0 -0.7 1193148.0 -171000.0 -0.34 -0.736 -0.9455 3630330 CBKinase1_020304 CC(C)C(NS(=O)(=O)c1cccc(C)c1)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L07 mock treatment 1664305.0 -160000.0 -0.3 1180427.0 -183000.0 -0.37 -0.4711 -0.995 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L08 mock treatment 1649824.0 -174000.0 -0.33 1318751.0 -45100.0 -0.09 -0.2949 -0.8697 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L09 compound treatment 1398244.0 -426000.0 -0.8 1154409.0 -209000.0 -0.42 -0.8611 -0.9545 3630331 CBKinase1_020305 Oc1ccnc(SCC(=O)Nc2ccc(cc2)[N+](=O)[O-])n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L10 compound treatment 1666082.0 -158000.0 -0.3 1389494.0 25600.0 0.05 -0.1733 -0.5763 3630332 CBKinase1_020306 Fc1ccc(NC(=O)CC2NC(=O)NC2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L11 compound treatment 1783368.0 -40600.0 -0.08 1476891.0 113000.0 0.23 0.1059 0.4442 3630333 CBKinase1_020307 Clc1ccccc1n2c(CSc3ncnc4[nH]cnc34)nc5ccccc5c2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L12 compound treatment 1645991.0 -178000.0 -0.33 1339856.0 -24000.0 -0.05 -0.2701 -0.8004 3630334 CBKinase1_020308 Cc1cc(SCC(=O)Nc2ccc(SC(F)F)cc2)nc3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L13 compound treatment 1782870.0 -41100.0 -0.08 1522437.0 159000.0 0.32 0.1696 0.52 3630335 CBKinase1_020309 COc1ccc(NC(=O)C2(CCCC2)c3ccc(NC(=O)c4ccc(OC(=O)C)cc4)cc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L14 compound treatment 1559759.0 -264000.0 -0.5 1431590.0 67700.0 0.14 -0.255 -0.4959 3630336 CBKinase1_020310 CC(C)C(NCCC(O)c1ccc(Br)cc1)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L15 mock treatment 1369497.0 -454000.0 -0.85 1285470.0 -78400.0 -0.16 -0.714 -0.8232 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L16 mock treatment 1619830.0 -204000.0 -0.38 1138192.0 -226000.0 -0.45 -0.5899 -0.9967 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L17 compound treatment 1723958.0 -100000.0 -0.19 1546862.0 183000.0 0.37 0.1259 0.3063 3630337 CBKinase1_020311 Fc1ccc(NC(=O)Cn2cnc3sc(cc3c2=O)c4ccccc4)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L18 compound treatment 1528913.0 -295000.0 -0.55 1189031.0 -175000.0 -0.35 -0.6387 -0.9753 3630338 CBKinase1_020312 OC(=O)CSc1nc2cc(F)c(F)cc2[nH]1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L19 compound treatment 1076737.0 -747000.0 -1.4 1006049.0 -358000.0 -0.72 -1.4976 -0.9511 3630339 CBKinase1_020313 Cc1ccc(O)c(NC(=S)NC(=O)c2ccc(o2)c3ccccc3[N+](=O)[O-])c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L20 compound treatment 1344230.0 -480000.0 -0.9 1375748.0 11900.0 0.02 -0.62 -0.6882 3630340 CBKinase1_020314 CC(=O)c1ccc(NC(=O)CSc2ncnc3c4cc5COC(C)(C)Cc5nc4sc23)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L21 compound treatment 1212722.0 -611000.0 -1.15 1082614.0 -281000.0 -0.56 -1.2088 -0.9461 3630341 CBKinase1_020315 Oc1ccnc(SCC(=O)Nc2ccc(Oc3ccccc3)cc2)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L22 compound treatment 1481716.0 -342000.0 -0.64 1319743.0 -44100.0 -0.09 -0.5166 -0.7967 3630342 CBKinase1_020316 COC(=O)Cc1cc(O)n(n1)c2nc3ccccc3[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L23 mock treatment 1174661.0 -649000.0 -1.22 1187447.0 -176000.0 -0.35 -1.1112 -0.8757 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 L24 mock treatment 1191465.0 -632000.0 -1.19 981082.0 -383000.0 -0.77 -1.3806 -0.9774 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M01 compound treatment 1302135.0 -522000.0 -0.98 1104618.0 -259000.0 -0.52 -1.059 -0.9557 3630343 CBKinase1_020317 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2cccc(c2)C(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M02 compound treatment 1643560.0 -180000.0 -0.34 1248187.0 -116000.0 -0.23 -0.4029 -0.9827 3630344 CBKinase1_020318 Cc1nnc(SCC(=O)N2CCC(CC2)c3noc4ccc(F)cc34)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M03 compound treatment 1672574.0 -151000.0 -0.28 1400033.0 36200.0 0.07 -0.1498 -0.5109 3630345 CBKinase1_020319 Cc1cc(C)n(n1)S(=O)(=O)c2cccc3ccc(C)nc23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M04 compound treatment 1367045.0 -457000.0 -0.86 1350118.0 -13700.0 -0.03 -0.6259 -0.7294 3630346 CBKinase1_020320 Cn1c(SCC(=O)Nc2c(Cl)cccc2Cl)nnc1c3ccc(NC(=O)c4ccc(F)cc4)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M05 compound treatment 1808770.0 -15200.0 -0.03 1534561.0 171000.0 0.34 0.2211 0.6459 3630347 CBKinase1_020321 Nc1nc(SCC(=O)c2ccc(cc2)c3ccccc3)n[nH]1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M06 compound treatment 1495940.0 -328000.0 -0.62 1133290.0 -231000.0 -0.46 -0.7613 -0.9898 3630348 CBKinase1_020322 Cc1ccccc1OCCn2c(nc3ccccc23)C(O)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M07 compound treatment 1597954.0 -226000.0 -0.42 1272909.0 -90900.0 -0.18 -0.4285 -0.9284 3630349 CBKinase1_020323 COc1ccc(c(OC)c1)S(=O)(=O)n2cc(c(N)n2)c3ccc(C)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M08 compound treatment 1749705.0 -74200.0 -0.14 1605210.0 241000.0 0.48 0.2426 0.4831 3630350 CBKinase1_020324 Ic1ccc(cc1)N2C(=O)CC(SCC(=O)Nc3ccccc3)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M09 mock treatment 1730870.0 -93100.0 -0.17 1693262.0 329000.0 0.66 0.342 0.5021 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M10 mock treatment 1616483.0 -207000.0 -0.39 1330764.0 -33100.0 -0.07 -0.3221 -0.8155 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M11 compound treatment 1684890.0 -139000.0 -0.26 1530332.0 166000.0 0.33 0.0507 0.1199 3630351 CBKinase1_020325 OCCCNC(=O)C(=O)NCC1COc2ccccc2O1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M12 compound treatment 1814014.0 -9920.0 -0.02 1693300.0 329000.0 0.66 0.4524 0.6868 3630352 CBKinase1_020326 COc1ccc(cc1)C2CC(=O)c3cnc(NCCN4CCOCC4)nc3C2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M13 mock treatment 1823202.0 -727.0 0.0 1666765.0 303000.0 0.61 0.4271 0.7055 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M14 mock treatment 1837678.0 13700.0 0.03 1754025.0 390000.0 0.78 0.5697 0.7301 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M15 compound treatment 1741913.0 -82000.0 -0.15 1563371.0 200000.0 0.4 0.1731 0.4049 3630353 CBKinase1_020327 CCc1ccc(CCC(=O)Nc2ccc(I)cc2)o1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M16 compound treatment 1995016.0 171000.0 0.32 1628607.0 265000.0 0.53 0.6013 0.9714 3630354 CBKinase1_020328 COc1cc(Cl)c(C)cc1NC(=O)CC2Sc3ccccc3NC2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M17 compound treatment 1713307.0 -111000.0 -0.21 1709079.0 345000.0 0.69 0.341 0.4733 3630355 CBKinase1_020329 COc1ccc(NC(=O)Cc2nc(cs2)c3ccc(OC)cc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M18 compound treatment 1808689.0 -15200.0 -0.03 1026131.0 -338000.0 -0.68 -0.4975 -0.7364 3630356 CBKinase1_020330 COc1cc(CNCc2ccccc2)cc(I)c1OCC#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M19 compound treatment 2046545.0 223000.0 0.42 1410689.0 46800.0 0.09 0.3617 0.8446 3630357 CBKinase1_020331 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2cccc(Cl)c2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M20 compound treatment 2075255.0 251000.0 0.47 1671618.0 308000.0 0.62 0.7686 0.9914 1986402 CBKinase1_020332 CN(C(=O)CN1C(=O)c2ccccc2S1(=O)=O)c3ccccc3C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M21 compound treatment 1779935.0 -44000.0 -0.08 1631694.0 268000.0 0.54 0.3201 0.591 3630358 CBKinase1_020333 O=C(Cn1c(nc2ccccc12)c3ccccn3)NCCN4CCOCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M22 compound treatment 1839988.0 16100.0 0.03 1578985.0 215000.0 0.43 0.3254 0.7548 3630359 CBKinase1_020334 OC(=O)CCNS(=O)(=O)c1cccc(Cl)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M23 compound treatment 1848419.0 24500.0 0.05 383635.0 -980000.0 -1.96 -1.3528 -0.6903 3630360 CBKinase1_020335 Cc1ccccc1NC(=O)CSc2nc(N)c(C#N)cc2C#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 M24 compound treatment 1497563.0 -326000.0 -0.61 1061376.0 -302000.0 -0.6 -0.8607 -1.0 3630361 CBKinase1_020336 O=C(CSC1=C(C#N)C2(CCCCC2)C(C#N)C(=O)N1)Nc3cccc4cccnc34 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N01 compound treatment 1291973.0 -532000.0 -1.0 891825.0 -472000.0 -0.94 -1.3733 -0.9996 3630362 CBKinase1_020337 COc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccc(F)cc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N02 compound treatment 1624644.0 -199000.0 -0.37 1180518.0 -183000.0 -0.37 -0.5237 -0.9999 3630363 CBKinase1_020338 Fc1ccc(NC(=O)C2CC(=O)n3ncnc3N2)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N03 compound treatment 1394951.0 -429000.0 -0.81 1255306.0 -109000.0 -0.22 -0.7229 -0.8667 3630364 CBKinase1_020339 Cc1cc(C(=O)CSc2nc[nH]n2)c(C)n1c3cc(Cl)ccc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N04 compound treatment 1713745.0 -110000.0 -0.21 1409392.0 45500.0 0.09 -0.0819 -0.3625 1432672 CBKinase1_020340 CCOC(=O)c1c(NC(=O)c2ccco2)scc1C3COc4ccccc4O3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N05 compound treatment 1707708.0 -116000.0 -0.22 944740.0 -419000.0 -0.84 -0.7466 -0.8625 3630365 CBKinase1_020341 O=C(Cn1c(nc2ccccc12)c3ccccn3)NCc4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N06 compound treatment 1609129.0 -215000.0 -0.4 1158044.0 -206000.0 -0.41 -0.576 -1.0 3630366 CBKinase1_020342 COC(=O)c1ccc(cc1)N2C(=O)CC(SCCc3nc4ccccc4[nH]3)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N07 compound treatment 1289440.0 -534000.0 -1.0 1098888.0 -265000.0 -0.53 -1.084 -0.9554 3630367 CBKinase1_020343 COc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccc(I)cc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N08 compound treatment 1989880.0 166000.0 0.31 2241037.0 877000.0 1.75 1.46 0.8199 3630368 CBKinase1_020344 COc1cccc(NC(=O)CC2NC3CCCCC3NC2=O)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N09 mock treatment 1905664.0 81700.0 0.15 1127847.0 -236000.0 -0.47 -0.225 -0.4537 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N10 mock treatment 1852229.0 28300.0 0.05 1506671.0 143000.0 0.29 0.2394 0.8246 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N11 compound treatment 1387695.0 -436000.0 -0.82 1172558.0 -191000.0 -0.38 -0.8495 -0.9398 3630369 CBKinase1_020345 COc1ccc(CCNc2nc(cs2)c3ccncc3)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N12 compound treatment 1944753.0 121000.0 0.23 1726874.0 363000.0 0.73 0.6734 0.8859 3630370 CBKinase1_020346 Cc1sc2ncn(CC(=O)Nc3ccc(F)c(Cl)c3)c(=O)c2c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N13 mock treatment 1998904.0 175000.0 0.33 1659668.0 296000.0 0.59 0.6503 0.9615 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N14 mock treatment 1748346.0 -75600.0 -0.14 1529557.0 166000.0 0.33 0.1338 0.3715 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N15 compound treatment 1782354.0 -41600.0 -0.08 1806010.0 442000.0 0.88 0.5697 0.6422 3630371 CBKinase1_020347 CCn1c(SCC(=O)Nc2ccc(F)cc2)nnc1c3cccs3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N16 compound treatment 2237923.0 414000.0 0.78 1632868.0 269000.0 0.54 0.9298 0.9838 3630372 CBKinase1_020348 COc1ccc(NC(=O)NCCCN2CCCC2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N17 compound treatment 1350516.0 -473000.0 -0.89 1496714.0 133000.0 0.27 -0.4407 -0.4751 3630373 CBKinase1_020349 COc1cc(OC)c(NC(=O)CSc2ccccn2)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N18 compound treatment 1866467.0 42500.0 0.08 1714805.0 351000.0 0.7 0.5525 0.7826 3630374 CBKinase1_020350 COC(=O)CSc1ncnc2c3cc4COC(C)(C)Cc4nc3sc12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N19 compound treatment 2298821.0 475000.0 0.89 1665147.0 301000.0 0.6 1.0562 0.9818 3630375 CBKinase1_020351 Cc1occc1c2nnc3sc(nn23)c4ccc(o4)c5ccccc5[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N20 compound treatment 1931955.0 108000.0 0.2 1622681.0 259000.0 0.52 0.5092 0.9164 3630376 CBKinase1_020352 COc1ccc(cc1)C(=O)NCCNc2ccc(cc2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N21 compound treatment 1838376.0 14400.0 0.03 1767158.0 403000.0 0.81 0.5892 0.7305 3630377 CBKinase1_020353 Nc1nnc(SCC(=O)N2CCN(Cc3ccccc3)CC2)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N22 compound treatment 1795610.0 -28300.0 -0.05 1607729.0 244000.0 0.49 0.3071 0.6263 3630378 CBKinase1_020354 Cc1ccc(cc1C)n2ncc(C(=O)NCc3ccccn3)c2NC(=O)c4ccco4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N23 compound treatment 1763293.0 -60600.0 -0.11 1661896.0 298000.0 0.6 0.3407 0.5618 3630379 CBKinase1_020355 CC(=O)c1cn(CC(=O)Nc2ccccc2)c3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 N24 compound treatment 1226875.0 -597000.0 -1.12 1095136.0 -269000.0 -0.54 -1.1724 -0.9432 3630380 CBKinase1_020356 Fc1ccc(NC(=O)CSc2nc3ccccc3c(=O)[nH]2)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O01 compound treatment 995682.0 -828000.0 -1.55 728456.0 -635000.0 -1.27 -1.9975 -0.995 1359112 CBKinase1_020357 Cc1cc(C)c(C)c(c1C)S(=O)(=O)NCCC(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O02 compound treatment 944084.0 -880000.0 -1.65 867440.0 -496000.0 -0.99 -1.8696 -0.9703 3630381 CBKinase1_020358 Cc1ccccc1N2C(=O)CC(SCC(=O)Nc3ccccc3)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O03 compound treatment 1152895.0 -671000.0 -1.26 862792.0 -501000.0 -1.0 -1.5989 -0.9935 3630382 CBKinase1_020359 Cc1cc(C)nc(NS(=O)(=O)c2ccc(Nc3nc(cs3)c4ccc(F)cc4)cc2)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O04 compound treatment 987676.0 -836000.0 -1.57 895742.0 -468000.0 -0.94 -1.7717 -0.9694 3630383 CBKinase1_020360 COc1ccc(OC)c(NC(=O)c2cnn(c2NC(=O)c3ccco3)c4ccccc4Cl)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O05 compound treatment 904740.0 -919000.0 -1.73 826871.0 -537000.0 -1.07 -1.9791 -0.9739 1527577 CBKinase1_020361 O=C(CN1C(=O)c2ccccc2S1(=O)=O)Nc3ccc(cc3)N4CCOCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O06 compound treatment 921981.0 -902000.0 -1.69 871366.0 -492000.0 -0.98 -1.8933 -0.9667 3630384 CBKinase1_020362 CCc1ccc(CCC(=O)Nc2cc(Cl)ccc2Cl)o1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O07 compound treatment 1090478.0 -733000.0 -1.38 805919.0 -558000.0 -1.12 -1.7622 -0.9945 3630385 CBKinase1_020363 Brc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(c3)C(=O)N4CCOCC4)o2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O08 compound treatment 877117.0 -947000.0 -1.78 930908.0 -433000.0 -0.87 -1.8688 -0.9453 3630386 CBKinase1_020364 Nc1ncnc(NCc2cccnc2)c1[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O09 compound treatment 1081174.0 -743000.0 -1.39 961579.0 -402000.0 -0.8 -1.5545 -0.9658 3630387 CBKinase1_020365 COc1ccc(cc1)c2nnc(SCc3ccc([N+](=O)[O-])c(OC)c3)n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O10 compound treatment 1112324.0 -712000.0 -1.34 908318.0 -456000.0 -0.91 -1.5884 -0.9825 3630388 CBKinase1_020366 CC(=O)c1cccc(NC(=O)c2ccc(CNS(=O)(=O)c3ccc(cc3)C(C)(C)C)cc2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O11 mock treatment 1005820.0 -818000.0 -1.54 1038620.0 -325000.0 -0.65 -1.5457 -0.9268 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O12 mock treatment 924904.0 -899000.0 -1.69 1001311.0 -363000.0 -0.72 -1.7058 -0.9287 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O13 compound treatment 1019949.0 -804000.0 -1.51 866549.0 -497000.0 -0.99 -1.7701 -0.9795 3630389 CBKinase1_020367 COC(=O)c1ccccc1NC(=O)CSc2nnc(o2)c3ccc(C)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O14 compound treatment 1102257.0 -722000.0 -1.35 1077208.0 -287000.0 -0.57 -1.3631 -0.9267 3630390 CBKinase1_020368 Cn1ncc(C#N)c1NC(=O)C2CC(=NO2)c3c(F)cccc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O15 compound treatment 1087229.0 -737000.0 -1.38 852786.0 -511000.0 -1.02 -1.7002 -0.9889 3630391 CBKinase1_020369 [O-][N+](=O)c1ccccc1c2ccc(o2)c3nn4c(nnc4s3)c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O16 compound treatment 1219602.0 -604000.0 -1.13 963643.0 -400000.0 -0.8 -1.3678 -0.9854 1986267 CBKinase1_020370 CC(=O)Nc1ccc(Br)cc1c2nc3ccccc3nc2O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O17 compound treatment 1095391.0 -729000.0 -1.37 1038913.0 -325000.0 -0.65 -1.4264 -0.9421 3630392 CBKinase1_020371 Cc1nc2ccccc2nc1OCc3cccc(c3)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O18 compound treatment 775116.0 -1050000.0 -1.97 668188.0 -696000.0 -1.39 -2.3755 -0.9855 3630393 CBKinase1_020372 Cc1ccc(cc1C)c2csc3nnc(SCC(=O)c4ccc5OCCOc5c4)n23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O19 compound treatment 1444607.0 -379000.0 -0.71 974804.0 -389000.0 -0.78 -1.0534 -0.999 3630394 CBKinase1_020373 CCc1ccc(CCC(=O)Nc2ccc(C)cc2C)o1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O20 compound treatment 959245.0 -865000.0 -1.62 749826.0 -614000.0 -1.23 -2.0156 -0.9905 3630395 CBKinase1_020374 COc1ccc(cc1)c2nnc(SCCC(=O)O)n2c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O21 compound treatment 1114064.0 -710000.0 -1.33 993917.0 -370000.0 -0.74 -1.4652 -0.9614 3630396 CBKinase1_020375 CC(Oc1ccc(Cl)cc1Cl)C(=O)NC(=S)Nc2sc3CCCCc3c2C#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O22 compound treatment 1310549.0 -513000.0 -0.96 1145252.0 -219000.0 -0.44 -0.9905 -0.936 3630397 CBKinase1_020376 COc1ccc(cc1N(C)S(=O)(=O)c2ccccc2)S(=O)(=O)n3nc(C)cc3C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O23 compound treatment 1324351.0 -500000.0 -0.94 867058.0 -497000.0 -0.99 -1.3653 -0.9996 3630398 CBKinase1_020377 COc1ccccc1NC(=O)c2ccc(OCC(=O)Nc3ccccc3F)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 O24 compound treatment 984825.0 -839000.0 -1.58 790790.0 -573000.0 -1.15 -1.9238 -0.9877 3630399 CBKinase1_020378 Cc1ccc(cc1)S(=O)(=O)NC(=O)CSc2nc3ccccc3s2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P01 compound treatment 749497.0 -1070000.0 -2.02 595407.0 -768000.0 -1.54 -2.5123 -0.991 3630400 CBKinase1_020379 Cc1cccc(NC(=O)c2cc(NC(=O)CCC(=O)O)ccc2N3CCOCC3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P02 compound treatment 788819.0 -1040000.0 -1.94 639107.0 -725000.0 -1.45 -2.3984 -0.9895 3630401 CBKinase1_020380 CCOC(=O)c1sc2ncn(CC(=O)Nc3ccc(F)c(Cl)c3)c(=O)c2c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P03 compound treatment 863830.0 -960000.0 -1.8 748555.0 -615000.0 -1.23 -2.1441 -0.9826 3630402 CBKinase1_020381 Cc1ccc(Oc2coc3cc(OCC(=O)Nc4ccccc4C(F)(F)F)ccc3c2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P04 compound treatment 791714.0 -1030000.0 -1.94 741782.0 -622000.0 -1.24 -2.2494 -0.977 3630403 CBKinase1_020382 COC(=O)c1c(NC(=O)CN2C(=O)c3ccccc3C2=O)sc4CC(CCc14)C(C)(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P05 compound treatment 927863.0 -896000.0 -1.68 740890.0 -623000.0 -1.25 -2.0699 -0.989 3630404 CBKinase1_020383 Cc1nnc2sc(nn12)c3cccc(NC(=O)c4cccnc4)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P06 compound treatment 1022625.0 -801000.0 -1.5 680438.0 -683000.0 -1.37 -2.0296 -0.9988 3630405 CBKinase1_020384 CC(C)N(Cc1nc(no1)c2ccc(C)cc2)C(=O)c3ccc(cc3)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P07 compound treatment 1114638.0 -709000.0 -1.33 1078610.0 -285000.0 -0.57 -1.3447 -0.9283 3630406 CBKinase1_020385 COc1ccc(cc1)c2nc(NC(=O)CSc3nnc(C)s3)ns2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P08 compound treatment 1149738.0 -674000.0 -1.27 838589.0 -525000.0 -1.05 -1.6373 -0.9957 1977531 CBKinase1_020386 O=C(NCCCN1CCOCC1)c2ccc3nc(c4ccccc4)c(nc3c2)c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P09 compound treatment 1075002.0 -749000.0 -1.41 878114.0 -486000.0 -0.97 -1.6807 -0.9837 3630407 CBKinase1_020387 CCOc1c(OC)cccc1C2C(=C(C)Nc3ncnn23)C(=O)Nc4ccccc4OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P10 compound treatment 1014693.0 -809000.0 -1.52 665812.0 -698000.0 -1.4 -2.0608 -0.9991 3630408 CBKinase1_020388 [O-][N+](=O)c1ccc(NCCNCc2cccnc2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P11 mock treatment 1049539.0 -774000.0 -1.45 810364.0 -553000.0 -1.11 -1.8102 -0.9909 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P12 mock treatment 1322068.0 -502000.0 -0.94 918481.0 -445000.0 -0.89 -1.2957 -0.9996 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P13 compound treatment 752777.0 -1070000.0 -2.01 552702.0 -811000.0 -1.62 -2.5683 -0.9943 3630409 CBKinase1_020389 CC(C)(CO)NCC(O)COc1ccccc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P14 compound treatment 1106990.0 -717000.0 -1.35 762997.0 -601000.0 -1.2 -1.8009 -0.9984 3630410 CBKinase1_020390 COCCCNc1ncnc(N)c1[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P15 compound treatment 1088568.0 -735000.0 -1.38 888766.0 -475000.0 -0.95 -1.6476 -0.9833 3630411 CBKinase1_020391 Fc1ccc(cc1)n2c(CNCC3CCCO3)nc4ccccc4c2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P16 compound treatment 1159502.0 -664000.0 -1.25 993718.0 -370000.0 -0.74 -1.4051 -0.9689 3630412 CBKinase1_020392 Nc1ncnc(Nc2ccccn2)c1[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P17 compound treatment 973677.0 -850000.0 -1.6 861384.0 -502000.0 -1.0 -1.8388 -0.9751 3630413 CBKinase1_020393 CCn1c(SCC(=O)Nc2ccccc2Br)nnc1c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P18 compound treatment 1029449.0 -794000.0 -1.49 815869.0 -548000.0 -1.1 -1.8291 -0.9885 3630414 CBKinase1_020394 CC(=O)Nc1nonc1c2nc3ccccc3n2Cc4cccc5ccccc45 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P19 compound treatment 1019321.0 -805000.0 -1.51 1027477.0 -336000.0 -0.67 -1.5435 -0.9335 3630415 CBKinase1_020395 COc1ccc(cc1CSc2nnc(c3ccccc3O)n2c4ccccc4)C(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P20 compound treatment 1244424.0 -580000.0 -1.09 1192671.0 -171000.0 -0.34 -1.0112 -0.8867 3630416 CBKinase1_020396 O=C(CSc1nc[nH]n1)Nc2ccc3OCCOc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P21 compound treatment 686931.0 -1140000.0 -2.13 557714.0 -806000.0 -1.61 -2.6487 -0.9904 3630417 CBKinase1_020397 Cn1c(SCC(=O)N2CCN(CC2)c3ccccc3)nnc1c4cc5ccccc5o4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P22 compound treatment 960361.0 -864000.0 -1.62 912016.0 -452000.0 -0.9 -1.7849 -0.9618 3630418 CBKinase1_020398 Brc1ccc(cc1)c2csc(Cc3nc(cs3)c4cc5ccccc5oc4=O)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P23 compound treatment 1016101.0 -808000.0 -1.52 727043.0 -637000.0 -1.27 -1.9724 -0.9962 3630419 CBKinase1_020399 Cc1cccc(c1C)n2c(SCC(=O)c3ccccc3)nnc2c4cccs4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2387 P24 compound treatment 856630.0 -967000.0 -1.82 681796.0 -682000.0 -1.36 -2.248 -0.99 3630420 CBKinase1_020400 O=C(CN1C(=O)CSc2ccccc12)Nc3ccccc3C(=O)N4CCOCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A01 compound treatment 1142459.0 -581000.0 -1.09 1023166.0 -706000.0 -1.41 -1.7691 -0.992 3630421 CBKinase1_020401 COc1ccc(cc1)N2C(=O)CC(SCCc3nc4ccccc4[nH]3)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A02 compound treatment 1420891.0 -303000.0 -0.57 1212946.0 -516000.0 -1.03 -1.1313 -0.9607 3630422 CBKinase1_020402 O=C(CCn1cnc2ccccc2c1=O)Nc3cccc(c3)C(=O)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A03 compound treatment 1160084.0 -564000.0 -1.06 1233635.0 -495000.0 -0.99 -1.4483 -0.9994 3630423 CBKinase1_020403 CC1(C)Cc2nc3nc(SCC(=O)Nc4ccccc4)nc(N)c3cc2CO1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A04 compound treatment 1457338.0 -266000.0 -0.5 1605634.0 -123000.0 -0.25 -0.5279 -0.9468 3630424 CBKinase1_020404 CCOc1ccc(NC(=O)CSc2n[nH]c(=O)n2c3ccccc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A05 compound treatment 1298080.0 -426000.0 -0.8 1311773.0 -417000.0 -0.83 -1.1546 -0.9998 3630425 CBKinase1_020405 Cn1ccnc1SCC(=O)Nc2cccc(F)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A06 compound treatment 1491852.0 -232000.0 -0.44 1303873.0 -425000.0 -0.85 -0.9086 -0.9518 3630426 CBKinase1_020406 CN(CC(=O)Nc1ccccc1c2ccccc2)S(=O)(=O)c3cc(Cl)ccc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A07 compound treatment 1456605.0 -267000.0 -0.5 1159391.0 -569000.0 -1.14 -1.1596 -0.9322 3630427 CBKinase1_020407 COc1cc(OC)c(NC(=O)CSc2nc3ccc(cc3s2)[N+](=O)[O-])cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A08 compound treatment 1641288.0 -82500.0 -0.15 1661359.0 -67500.0 -0.13 -0.205 -0.9976 3630428 CBKinase1_020408 COc1ccc(cc1OC)c2nnc(SCC(=O)Nc3c(C)n[nH]c3C)n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A09 compound treatment 1644928.0 -78900.0 -0.15 1716182.0 -12700.0 -0.03 -0.1227 -0.8165 3630429 CBKinase1_020409 Cc1ccc(OCCCCSc2nc(C)cc(O)n2)c(C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A10 compound treatment 1583728.0 -140000.0 -0.26 1563201.0 -166000.0 -0.33 -0.4201 -0.9935 3630430 CBKinase1_020410 CCOc1cccc(c1)c2nnc(SCC(=O)n3c4CCCCc4c5ccccc35)n2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A11 compound treatment 1370599.0 -353000.0 -0.66 1607671.0 -121000.0 -0.24 -0.6402 -0.9068 3630431 CBKinase1_020411 Cc1cc(OCC(=O)Nc2cccc(c2)c3nnc(o3)c4ccccc4)cc(C)c1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A12 compound treatment 1288729.0 -435000.0 -0.82 1494502.0 -234000.0 -0.47 -0.9088 -0.9652 3630432 CBKinase1_020412 [O-][N+](=O)c1cccc(c1)c2noc(CCN3C(=O)c4ccccc4C3=O)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A13 mock treatment 1685330.0 -38500.0 -0.07 1262738.0 -466000.0 -0.93 -0.7099 -0.7596 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A14 mock treatment 1240540.0 -483000.0 -0.91 1737868.0 8980.0 0.02 -0.6288 -0.693 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A15 compound treatment 255786.0 -1470000.0 -2.76 258140.0 -1470000.0 -2.94 -4.0273 -0.9995 3630433 CBKinase1_020413 Oc1c(cc(Cl)c2cccnc12)C(Nc3ccccn3)c4ccc(cc4)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A16 compound treatment 1592814.0 -131000.0 -0.25 1805917.0 77000.0 0.15 -0.065 -0.2241 3630434 CBKinase1_020414 Cc1cc(Cl)c(OCCCSc2nc(C)cc(O)n2)c(Br)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A17 compound treatment 1430857.0 -293000.0 -0.55 1450282.0 -279000.0 -0.56 -0.7826 -1.0 3630435 CBKinase1_020415 Cc1ccc(OCCCSc2nc(C)cc(O)n2)c(I)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A18 compound treatment 907713.0 -816000.0 -1.53 889105.0 -840000.0 -1.68 -2.2702 -0.999 3630436 CBKinase1_020416 CN(CC(=O)Nc1ccc(cc1)[N+](=O)[O-])S(=O)(=O)c2cc(Cl)ccc2Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A19 compound treatment 1786673.0 62900.0 0.12 1683716.0 -45200.0 -0.09 0.0196 0.132 3630437 CBKinase1_020417 Cc1cc(n2nc3ccccc3n2)c4oc(SCc5nnc(o5)c6ccccc6)nc4c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A20 compound treatment 1320447.0 -403000.0 -0.76 1283839.0 -445000.0 -0.89 -1.1644 -0.9968 3630438 CBKinase1_020418 CN(CC(=O)Nc1ccncc1)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A21 compound treatment 1090861.0 -633000.0 -1.19 1102044.0 -627000.0 -1.25 -1.7261 -0.9996 3630439 CBKinase1_020419 COC(=O)c1ccccc1NC(=O)c2ccc(NC(=O)COc3ccccc3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A22 compound treatment 1245554.0 -478000.0 -0.9 1248011.0 -481000.0 -0.96 -1.3145 -0.9994 3630440 CBKinase1_020420 COc1ccc(cc1NC(=O)c2ccccc2OCC(=O)Nc3cccc(C)c3)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A23 compound treatment 1471270.0 -253000.0 -0.47 1258989.0 -470000.0 -0.94 -0.9993 -0.9499 3630441 CBKinase1_020421 CC(=O)c1cccc(NC(=O)CSc2nnc(c3cc4ccccc4cc3O)n2C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 A24 compound treatment 949979.0 -774000.0 -1.45 869447.0 -859000.0 -1.72 -2.2419 -0.9965 3630442 CBKinase1_020422 CN(CC(=O)Nc1ccc(C#N)cc1)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B01 compound treatment 1202268.0 -522000.0 -0.98 1408722.0 -320000.0 -0.64 -1.1448 -0.9788 3630443 CBKinase1_020423 CC1(C)NC(=O)N(CCCCOc2ccccc2[N+](=O)[O-])C1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B02 compound treatment 1704922.0 -18900.0 -0.04 1907117.0 178000.0 0.36 0.2268 0.6336 3630444 CBKinase1_020424 Cc1ccc(c(c1)[N+](=O)[O-])S(=O)(=O)Nc2cccc3cccnc23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B03 compound treatment 1756073.0 32300.0 0.06 1692224.0 -36700.0 -0.07 -0.009 -0.0944 3630445 CBKinase1_020425 CCC(=O)c1ccccc1OCCCN2C(=O)NC(C)(C)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B04 compound treatment 1945308.0 222000.0 0.42 1618524.0 -110000.0 -0.22 0.1381 0.2933 3630446 CBKinase1_020426 COc1cc(ccc1NC(=O)CN(C)S(=O)(=O)c2ccc3ccccc3c2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B05 compound treatment 1687593.0 -36200.0 -0.07 1653126.0 -75800.0 -0.15 -0.1551 -0.9347 3630447 CBKinase1_020427 CCOc1ccccc1NC(=O)CN2C(=O)c3ccc(cc3C2=O)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B06 compound treatment 1583000.0 -141000.0 -0.26 1952757.0 224000.0 0.45 0.1295 0.2492 3630448 CBKinase1_020428 CCCCN1C(=O)C(O)(CC(=O)c2ccco2)c3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B07 compound treatment 1833237.0 109000.0 0.21 1828683.0 99800.0 0.2 0.2863 0.9999 3630449 CBKinase1_020429 Cn1c(SCC(=O)n2c3CCCCc3c4ccccc24)nnc1c5ccco5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B08 compound treatment 1938750.0 215000.0 0.4 1692844.0 -36000.0 -0.07 0.2344 0.5718 3630450 CBKinase1_020430 CN(CC(=O)Nc1ccc(Cl)cc1C(F)(F)F)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B09 compound treatment 1077444.0 -646000.0 -1.21 1125651.0 -603000.0 -1.21 -1.7106 -1.0 3630451 CBKinase1_020431 CCC(C)S(=O)(=O)c1oc(nc1S(=O)(=O)c2ccccc2)c3ccc(C)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B10 compound treatment 1669590.0 -54200.0 -0.1 1780792.0 51900.0 0.1 0.0014 0.0096 3630452 CBKinase1_020432 CN(CC(=O)Nc1cccc(I)c1)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B11 compound treatment 1532551.0 -191000.0 -0.36 1722650.0 -6240.0 -0.01 -0.2627 -0.7312 3630453 CBKinase1_020433 Cc1ccccc1NC(=O)CSc2nnc(c3ccc(cc3)C(C)(C)C)n2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B12 compound treatment 1669563.0 -54200.0 -0.1 1825245.0 96400.0 0.19 0.0642 0.2946 3630454 CBKinase1_020434 Cc1ccc(C)c(OCCNS(=O)(=O)c2cc(ccc2C)[N+](=O)[O-])c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B13 mock treatment 1567968.0 -156000.0 -0.29 1823372.0 94500.0 0.19 -0.0733 -0.2106 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B14 mock treatment 2107835.0 384000.0 0.72 1805985.0 77100.0 0.15 0.6188 0.8393 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B15 compound treatment 1877956.0 154000.0 0.29 1719125.0 -9760.0 -0.02 0.1908 0.6579 3630455 CBKinase1_020435 Cc1nn(C)c(C)c1NC(=O)CSc2nnc(C)n2c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B16 compound treatment 1702349.0 -21500.0 -0.04 1844477.0 116000.0 0.23 0.1349 0.5752 3630456 CBKinase1_020436 OC(COc1ccc2ccccc2c1)Cn3cncn3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B17 compound treatment 1638404.0 -85400.0 -0.16 1634852.0 -94000.0 -0.19 -0.2463 -0.9969 3630457 CBKinase1_020437 O=C(Cn1c(=O)oc2ccccc12)Nc3ccc4c(c3)oc5ccccc54 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B18 compound treatment 2116505.0 393000.0 0.74 1963042.0 234000.0 0.47 0.8522 0.9759 3630458 CBKinase1_020438 CC(=O)Nc1ccc(OCC(O)Cn2nc(C)nc2C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B19 compound treatment 2344217.0 620000.0 1.16 1629994.0 -98900.0 -0.2 0.6838 0.5788 1439098 CBKinase1_020439 OC(=O)CCC(=O)Nc1ccc2C(=O)NC(=O)c2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B20 compound treatment 1430031.0 -294000.0 -0.55 1356392.0 -372000.0 -0.74 -0.9164 -0.9891 3630459 CBKinase1_020440 CC1(C)CC2=C(C(=O)C1)C(NC(=O)c3cccnc3)(C(=O)N2CCc4ccccc4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B21 compound treatment 1608100.0 -116000.0 -0.22 1596214.0 -133000.0 -0.27 -0.3411 -0.9951 3630460 CBKinase1_020441 O=C(CCN1C(=O)c2ccccc2S1(=O)=O)Nc3ccc(Oc4ccccc4)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B22 compound treatment 2001599.0 278000.0 0.52 1907795.0 179000.0 0.36 0.6216 0.9831 3630461 CBKinase1_020442 CCOC(=O)C1=C(C)NC(=O)C1(NC(=O)c2cccnc2)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B23 compound treatment 1367016.0 -357000.0 -0.67 1413006.0 -316000.0 -0.63 -0.9201 -0.9996 3630462 CBKinase1_020443 CC(=O)c1cccc(NC(=O)COc2ccccc2C(=O)Nc3ccccc3C#N)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 B24 compound treatment 1374286.0 -350000.0 -0.66 1046503.0 -682000.0 -1.36 -1.4284 -0.9438 3630463 CBKinase1_020444 Clc1ccc(cc1Cl)C2=NOC(C2)C(=O)Nc3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C01 compound treatment 1303313.0 -420000.0 -0.79 1386076.0 -343000.0 -0.69 -1.0427 -0.9975 3630464 CBKinase1_020445 Cn1c(nc2ccccc12)c3nonc3NC(=O)c4ccccc4Br 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C02 compound treatment 1267520.0 -456000.0 -0.86 1659614.0 -69300.0 -0.14 -0.7036 -0.8109 3630465 CBKinase1_020446 COc1ccc(cc1NC(=O)CN(C)S(=O)(=O)c2ccc(Cl)cc2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C03 compound treatment 1379786.0 -344000.0 -0.65 1824874.0 96000.0 0.19 -0.321 -0.4765 1454379 CBKinase1_020447 S=C(NCc1ccco1)Nc2cccnc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C04 compound treatment 1644499.0 -79300.0 -0.15 1370418.0 -358000.0 -0.72 -0.6119 -0.8362 3630466 CBKinase1_020448 COc1cc(OC)c(NC(=O)CN(C)S(=O)(=O)c2cc(Cl)ccc2Cl)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C05 compound treatment 1403477.0 -320000.0 -0.6 1681025.0 -47900.0 -0.1 -0.4929 -0.8094 3630467 CBKinase1_020449 Fc1ccccc1n2c(CSc3ncnc4ccccc34)nc5ccccc5c2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C06 compound treatment 1849646.0 126000.0 0.24 1441546.0 -287000.0 -0.57 -0.239 -0.3849 3630468 CBKinase1_020450 Clc1cc(NC(=O)CSc2nc3ccccc3o2)ccc1N4CCOCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C07 compound treatment 1410105.0 -314000.0 -0.59 1290379.0 -439000.0 -0.88 -1.0362 -0.9813 3630469 CBKinase1_020451 Cc1cc(Br)ccc1NC(=O)C(=O)NCCCN2CCOCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C08 compound treatment 1512352.0 -211000.0 -0.4 1562670.0 -166000.0 -0.33 -0.5156 -0.9961 3630470 CBKinase1_020452 Cc1cc(O)nc(SCCCOc2cccc(Br)c2)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C09 compound treatment 1226571.0 -497000.0 -0.93 1540715.0 -188000.0 -0.38 -0.926 -0.9201 3630471 CBKinase1_020453 Brc1c(OCC(=O)NCc2ccccn2)ccc3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C10 compound treatment 1611056.0 -113000.0 -0.21 1758862.0 30000.0 0.06 -0.1073 -0.4878 3630472 CBKinase1_020454 Cn1c(SCC(=O)c2ccc(cc2)[N+](=O)[O-])nnc1c3cc4ccccc4cc3O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C11 mock treatment 1247514.0 -476000.0 -0.89 1476540.0 -252000.0 -0.5 -0.9889 -0.9633 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C12 mock treatment 1313332.0 -410000.0 -0.77 2188652.0 460000.0 0.92 0.1049 0.0875 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C13 compound treatment 1339872.0 -384000.0 -0.72 1540697.0 -188000.0 -0.38 -0.7756 -0.954 3630473 CBKinase1_020455 CN(CC(=O)Nc1ccccc1C#N)S(=O)(=O)c2cc(Cl)ccc2Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C14 compound treatment 1200739.0 -523000.0 -0.98 1824110.0 95200.0 0.19 -0.5598 -0.5596 3630474 CBKinase1_020456 O=C(CCN1C(=O)c2ccccc2C1=O)Nc3ccccc3c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C15 mock treatment 1909678.0 186000.0 0.35 1840940.0 112000.0 0.22 0.4051 0.977 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C16 mock treatment 1512253.0 -212000.0 -0.4 2264423.0 536000.0 1.07 0.476 0.417 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C17 compound treatment 1546401.0 -177000.0 -0.33 1458777.0 -270000.0 -0.54 -0.6172 -0.9731 3630475 CBKinase1_020457 Nc1nnc(SCC(=O)NC2(CC3CC4CC(C3)C2)C4)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C18 compound treatment 1344982.0 -379000.0 -0.71 1558484.0 -170000.0 -0.34 -0.7437 -0.9432 3630476 CBKinase1_020458 COC(=O)c1ccccc1NC(=O)c2ccc(NC(=O)C3CCCO3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C19 compound treatment 255341.0 -1470000.0 -2.76 265725.0 -1460000.0 -2.92 -4.0172 -0.9996 3630477 CBKinase1_020459 Oc1c(cc(Cl)c2cccnc12)C(Nc3ccccn3)c4cccc(Br)c4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C20 compound treatment 1314126.0 -410000.0 -0.77 1518071.0 -211000.0 -0.42 -0.8418 -0.9599 3630478 CBKinase1_020460 CN(CC(=O)Nc1cccnc1)S(=O)(=O)c2cc(Cl)ccc2Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C21 compound treatment 355140.0 -1370000.0 -2.57 327837.0 -1400000.0 -2.8 -3.797 -0.9991 3630479 CBKinase1_020461 [O-][N+](=O)c1cccc(c1)S(=O)(=O)NCCOc2ccccc2c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C22 compound treatment 941807.0 -782000.0 -1.47 1362797.0 -366000.0 -0.73 -1.5555 -0.9483 3630480 CBKinase1_020462 COC(=O)c1ccccc1NC(=O)COc2ccc3ccccc3c2Br 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C23 compound treatment 1261305.0 -462000.0 -0.87 1289580.0 -439000.0 -0.88 -1.2348 -1.0 3630481 CBKinase1_020463 Cn1c(SCC(=O)Nc2ccc3c(c2)oc4ccccc43)nc5ccccc5c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 C24 compound treatment 944944.0 -779000.0 -1.46 953150.0 -776000.0 -1.55 -2.1303 -0.9996 3630482 CBKinase1_020464 COC(=O)c1ccccc1NC(=O)CSc2nnc(n2C)C3(CC4CC5CC(C4)C3)C5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D01 compound treatment 1245893.0 -478000.0 -0.9 1518764.0 -210000.0 -0.42 -0.9314 -0.9402 3630483 CBKinase1_020465 Cc1cc(O)nc(SCCOc2c(C)ccc(C)c2Cl)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D02 compound treatment 1520329.0 -203000.0 -0.38 1760760.0 31900.0 0.06 -0.2251 -0.5812 3630484 CBKinase1_020466 CCn1c(SCC(=O)NC(C)(C)C)nnc1c2cccc(c2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D03 compound treatment 1711290.0 -12500.0 -0.02 1587627.0 -141000.0 -0.28 -0.2162 -0.7633 3630485 CBKinase1_020467 O=C(COc1cccc(NC(=O)C2CCCCC2)c1)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D04 compound treatment 1629806.0 -94000.0 -0.18 1966821.0 238000.0 0.48 0.2115 0.4169 3630486 CBKinase1_020468 COc1ccc(NC(=O)C(C)Oc2ccccc2)cc1NC(=O)c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D05 compound treatment 1674988.0 -48800.0 -0.09 1824627.0 95700.0 0.19 0.0705 0.3323 3630487 CBKinase1_020469 COc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc(Cl)cc2)c(c1)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D06 compound treatment 1478159.0 -246000.0 -0.46 1827049.0 98200.0 0.2 -0.1874 -0.3738 3630488 CBKinase1_020470 Brc1c(OCC(=O)NCCN2CCOCC2)ccc3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D07 compound treatment 1452678.0 -271000.0 -0.51 1753242.0 24400.0 0.05 -0.3255 -0.6366 3630489 CBKinase1_020471 COc1ccc(NC(=O)COc2ccc3ccccc3c2Br)c(c1)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D08 compound treatment 1771886.0 48100.0 0.09 2100452.0 372000.0 0.74 0.589 0.7873 3630490 CBKinase1_020472 CCCSc1nnc(c(O)n1)c2cc(Br)ccc2NC(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D09 compound treatment 1662015.0 -61800.0 -0.12 2003187.0 274000.0 0.55 0.3056 0.5454 3630491 CBKinase1_020473 Cn1c(SCC(=O)Nc2cccc(c2)C(F)(F)F)nnc1c3ccc(F)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D10 compound treatment 1757113.0 33300.0 0.06 2020635.0 292000.0 0.58 0.4565 0.7785 3630492 CBKinase1_020474 COc1ccc(NC(=O)c2ccccc2OCC(=O)Nc3ccccc3C(F)(F)F)c(C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D11 mock treatment 1788595.0 64800.0 0.12 1781519.0 52600.0 0.11 0.1604 0.9974 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D12 mock treatment 2210501.0 487000.0 0.91 2052369.0 323000.0 0.65 1.1033 0.9857 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D13 compound treatment 2075016.0 351000.0 0.66 1838392.0 110000.0 0.22 0.621 0.8939 3630493 CBKinase1_020475 CCc1ccccc1NC(=O)CSc2nc3ccc(cc3[nH]2)C(=O)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D14 compound treatment 1562718.0 -161000.0 -0.3 1889912.0 161000.0 0.32 0.0137 0.0311 3630494 CBKinase1_020476 Brc1c(OCC(=O)Nc2ccccc2C(=O)N3CCCCC3)ccc4ccccc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D15 mock treatment 1540399.0 -183000.0 -0.34 2210126.0 481000.0 0.96 0.4367 0.4274 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D16 mock treatment 1995436.0 272000.0 0.51 2125758.0 397000.0 0.79 0.9215 0.9772 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D17 compound treatment 1734213.0 10400.0 0.02 1995617.0 267000.0 0.53 0.3908 0.7325 3630495 CBKinase1_020477 Cc1cccc(NC(=O)c2ccccc2OCC(=O)Nc3cccc(c3)[N+](=O)[O-])c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D18 compound treatment 2023538.0 300000.0 0.56 2266900.0 538000.0 1.08 1.1583 0.9544 3630496 CBKinase1_020478 Cc1nn(C(=O)c2ccco2)c(C)c1CN3C(=O)c4ccccc4C3=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D19 compound treatment 1473205.0 -251000.0 -0.47 1373918.0 -355000.0 -0.71 -0.8343 -0.9801 3630497 CBKinase1_020479 Cn1c(SCC(=O)NC2(CC3CC4CC(C3)C2)C4)nnc1c5cccc(c5)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D20 compound treatment 1542684.0 -181000.0 -0.34 1813021.0 84100.0 0.17 -0.1215 -0.3204 3630498 CBKinase1_020480 CC1(C)CC2=C(C(=O)C1)C(NC(=O)c3cccnc3)(C(=O)N2Cc4ccc(F)cc4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D21 compound treatment 1588028.0 -136000.0 -0.25 1633994.0 -94900.0 -0.19 -0.3143 -0.9894 3630499 CBKinase1_020481 Fc1ccccc1NC(=O)CCn2cnc3ccccc3c2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D22 compound treatment 1617147.0 -107000.0 -0.2 1472169.0 -257000.0 -0.51 -0.5044 -0.9158 3630500 CBKinase1_020482 COC(=O)C1=C(C)NC(=O)C1(Nc2ccc(Cl)cn2)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D23 compound treatment 1241949.0 -482000.0 -0.9 1301808.0 -427000.0 -0.85 -1.2432 -0.9996 3630501 CBKinase1_020483 CCOc1ccc(NC(=O)CSc2nnc(c3cc(Cl)ccc3O)n2C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 D24 compound treatment 1314399.0 -409000.0 -0.77 1113397.0 -615000.0 -1.23 -1.4133 -0.9744 3630502 CBKinase1_020484 Clc1ccc(cc1Cl)C2=NOC(C2)C(=O)NCc3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E01 mock treatment 975605.0 -748000.0 -1.4 1490330.0 -239000.0 -0.48 -1.3304 -0.8969 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E02 mock treatment 1370297.0 -354000.0 -0.66 1770855.0 42000.0 0.08 -0.41 -0.6129 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E03 compound treatment 1578935.0 -145000.0 -0.27 1609678.0 -119000.0 -0.24 -0.3608 -0.9978 3630503 CBKinase1_020485 COC(=O)c1ccccc1NC(=O)CSc2nnc(c3cc4cccc(OC)c4o3)n2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E04 compound treatment 1390150.0 -334000.0 -0.63 1731954.0 3070.0 0.01 -0.4386 -0.7002 3630504 CBKinase1_020486 COc1ccc(NC(=O)COc2cc(C)ccc2C)cc1NC(=O)c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E05 compound treatment 1615803.0 -108000.0 -0.2 1754006.0 25100.0 0.05 -0.1079 -0.5164 3630505 CBKinase1_020487 Fc1ccccc1C(=O)Nc2ccc(NC(=O)CN3C(=O)c4ccccc4C3=O)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E06 compound treatment 1979814.0 256000.0 0.48 2021202.0 292000.0 0.58 0.753 0.9953 3630506 CBKinase1_020488 OC(=O)CCC(=O)Nc1ccc(cc1)c2nc3cc(ccc3[nH]2)C(=O)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E07 compound treatment 1579282.0 -145000.0 -0.27 1381447.0 -347000.0 -0.69 -0.6829 -0.9159 3630507 CBKinase1_020489 Cc1nc(N)sc1c2nnc(SCC(=O)Nc3ccccc3C(F)(F)F)n2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E08 compound treatment 1567965.0 -156000.0 -0.29 1636873.0 -92000.0 -0.18 -0.3369 -0.975 3630508 CBKinase1_020490 CN(CC(=O)Nc1ccccc1C(=O)N)S(=O)(=O)c2cc(Cl)ccc2Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E09 mock treatment 1607478.0 -116000.0 -0.22 1633866.0 -95000.0 -0.19 -0.2887 -0.9976 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E10 mock treatment 2244688.0 521000.0 0.98 1666357.0 -62500.0 -0.12 0.6031 0.6118 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E11 compound treatment 1985565.0 262000.0 0.49 1726001.0 -2890.0 -0.01 0.3434 0.6988 3630509 CBKinase1_020491 Cc1ccc(NC(=O)CSc2nnc(c3ccc(Cl)cc3Cl)n2c4ccccc4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E12 compound treatment 2130370.0 407000.0 0.76 2515268.0 786000.0 1.57 1.6511 0.945 3630510 CBKinase1_020492 Cn1c(SCC(=O)n2c3CCCCc3c4ccccc24)nnc1c5cccc(c5)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E13 compound treatment 1828879.0 105000.0 0.2 2283310.0 554000.0 1.11 0.923 0.8201 3630511 CBKinase1_020493 COC(=O)COc1cccc(NC(=O)c2ccccc2F)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E14 compound treatment 1743975.0 20200.0 0.04 2227369.0 498000.0 1.0 0.7313 0.7335 3630512 CBKinase1_020494 Oc1cc(C(=O)OCc2cccc(c2)C(=O)Oc3ccccc3)c4ccccc4n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E15 compound treatment 1564629.0 -159000.0 -0.3 2122355.0 393000.0 0.79 0.3448 0.4098 3630513 CBKinase1_020495 COC(=O)c1ccccc1NC(=O)COc2ccc(Br)cc2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E16 compound treatment 1918932.0 195000.0 0.37 1789279.0 60400.0 0.12 0.3444 0.8929 3630514 CBKinase1_020496 COC(=O)COc1cccc(NC(=O)c2ccc(Cl)c(Cl)c2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E17 mock treatment 2049113.0 325000.0 0.61 2039524.0 311000.0 0.62 0.8709 1.0 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E18 mock treatment 1892704.0 169000.0 0.32 1750409.0 21500.0 0.04 0.2546 0.7957 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E19 compound treatment 1142880.0 -581000.0 -1.09 1414506.0 -314000.0 -0.63 -1.2155 -0.9657 3630515 CBKinase1_020497 Cc1ccc(OCCSc2nc(C)cc(O)n2)c(I)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E20 compound treatment 971058.0 -753000.0 -1.41 793930.0 -935000.0 -1.87 -2.3206 -0.9905 3630516 CBKinase1_020498 Cc1nnc(SCC(=O)n2c3CCCCc3c4CCCCc42)n1Cc5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E21 compound treatment 1300901.0 -423000.0 -0.79 1008166.0 -721000.0 -1.44 -1.58 -0.9606 3630517 CBKinase1_020499 Clc1ccc2n(C3CCCCC3)c(SCc4nnc(o4)c5ccccc5)nc2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E22 compound treatment 1953708.0 230000.0 0.43 1334761.0 -394000.0 -0.79 -0.2518 -0.2803 3630518 CBKinase1_020500 O=C(NCc1cccnc1)c2ccc3C(=O)N(Cc4cccnc4)C(=O)c3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E23 compound treatment 1510237.0 -214000.0 -0.4 1369079.0 -360000.0 -0.72 -0.792 -0.9619 3630519 CBKinase1_020501 CCc1ccccc1NC(=O)CSc2nc3cc(ccc3s2)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 E24 compound treatment 1401451.0 -322000.0 -0.61 1240180.0 -489000.0 -0.98 -1.1186 -0.9735 3630520 CBKinase1_020502 Cc1cc(O)nc(SCCCOc2ccc(cc2)[N+](=O)[O-])n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F01 mock treatment 1252204.0 -472000.0 -0.89 1755465.0 26600.0 0.05 -0.5885 -0.6635 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F02 mock treatment 1567153.0 -157000.0 -0.29 1735523.0 6640.0 0.01 -0.1986 -0.6745 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F03 compound treatment 1622916.0 -101000.0 -0.19 1765011.0 36100.0 0.07 -0.0829 -0.4088 3630521 CBKinase1_020503 COc1cc(NC(=O)COc2ccc(Cl)cc2C)c(cc1OC)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F04 compound treatment 1790585.0 66800.0 0.13 1828764.0 99900.0 0.2 0.2298 0.9749 3630522 CBKinase1_020504 CN(Cc1nc(no1)c2ccc(Br)cc2)S(=O)(=O)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F05 compound treatment 1750912.0 27100.0 0.05 1903401.0 175000.0 0.35 0.2826 0.8018 3630523 CBKinase1_020505 O=C(CC1c2ccccc2Oc3ccccc13)Nc4ccccc4C(=O)N5CCCCC5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F06 compound treatment 1842288.0 118000.0 0.22 1881671.0 153000.0 0.31 0.3732 0.9879 3630524 CBKinase1_020506 COc1cc(NC(=O)CN(C)S(=O)(=O)c2cc(Cl)ccc2Cl)cc(OC)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F07 compound treatment 1606944.0 -117000.0 -0.22 1798059.0 69200.0 0.14 -0.0574 -0.2212 3630525 CBKinase1_020507 CN(C(=O)COc1cccc(NC(=O)C)c1)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F08 compound treatment 1964197.0 240000.0 0.45 1780388.0 51500.0 0.1 0.3919 0.8466 3630526 CBKinase1_020508 CCc1ccc(OCCSc2nc(C)cc(O)n2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F09 mock treatment 1986303.0 263000.0 0.49 2406625.0 678000.0 1.35 1.3063 0.9062 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F10 mock treatment 1994995.0 271000.0 0.51 2133100.0 404000.0 0.81 0.9313 0.9752 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F11 compound treatment 1999848.0 276000.0 0.52 2195617.0 467000.0 0.93 1.0261 0.9615 3630527 CBKinase1_020509 [O-][N+](=O)c1cccc(NC(=O)COc2ccc(Cl)c3cccnc23)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F12 compound treatment 1746352.0 22600.0 0.04 1919273.0 190000.0 0.38 0.299 0.781 3630528 CBKinase1_020510 COc1ccc(NC(=O)CSc2nc3sc(C)c(C)c3c(=O)n2c4ccccc4)c(c1)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F13 compound treatment 2045417.0 322000.0 0.6 2128685.0 400000.0 0.8 0.992 0.9904 3630529 CBKinase1_020511 CC(=O)Nc1ccc(OCC(=O)Nc2ccc3c(c2)oc4ccccc43)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F14 compound treatment 2101056.0 377000.0 0.71 1690714.0 -38200.0 -0.08 0.4468 0.6273 3630530 CBKinase1_020512 [O-][N+](=O)c1cccc(c1)S(=O)(=O)N2CCN(CC(=O)Nc3ccc(F)cc3)CC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F15 compound treatment 2210482.0 487000.0 0.91 2260641.0 532000.0 1.06 1.3976 0.9972 3630531 CBKinase1_020513 COc1ccccc1NC(=O)CSc2nnc(c3ccc(F)cc3)n2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F16 compound treatment 2132560.0 409000.0 0.77 1966262.0 237000.0 0.47 0.8781 0.9733 3630532 CBKinase1_020514 CC(=O)c1c(C)nn(CC(O)COc2ccc3CCCc3c2)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F17 mock treatment 2060861.0 337000.0 0.63 2162830.0 434000.0 0.87 1.0607 0.988 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F18 mock treatment 2099494.0 376000.0 0.71 2483405.0 755000.0 1.51 1.5651 0.9401 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F19 compound treatment 1734127.0 10300.0 0.02 1772040.0 43200.0 0.09 0.0747 0.845 3630533 CBKinase1_020515 Clc1ccc(cc1)C(=O)Nc2cccc(CCc3ccccn3)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F20 compound treatment 1240710.0 -483000.0 -0.91 1101311.0 -628000.0 -1.25 -1.5282 -0.9873 3630534 CBKinase1_020516 COc1cc(cc(OC)c1OC)C(=O)NC2(C(=O)N(Cc3ccco3)C4=C2C(=O)CC(C)(C)C4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F21 compound treatment 1565104.0 -159000.0 -0.3 2018248.0 289000.0 0.58 0.1983 0.3048 1377205 CBKinase1_020517 O=C(CCN1C(=O)c2ccccc2C1=O)Nc3ccc4OCCOc4c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F22 compound treatment 533407.0 -1190000.0 -2.23 647029.0 -1080000.0 -2.16 -3.1092 -0.9999 3630535 CBKinase1_020518 CC1=C(C(=O)c2ccccc2)C(NC(=O)c3ccncc3)(C(=O)N1Cc4ccccc4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F23 compound treatment 1266871.0 -457000.0 -0.86 1362610.0 -366000.0 -0.73 -1.1242 -0.9969 3630536 CBKinase1_020519 COc1ccc(CCNS(=O)(=O)c2cc(ccc2C)[N+](=O)[O-])cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 F24 compound treatment 1235191.0 -489000.0 -0.92 1307095.0 -422000.0 -0.84 -1.2447 -0.9991 3630537 CBKinase1_020520 Clc1ccc(cc1Cl)C2=NOC(C2)C(=O)NCc3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G01 compound treatment 1288116.0 -436000.0 -0.82 1443175.0 -286000.0 -0.57 -0.9822 -0.9846 1848197 CBKinase1_020521 CCOc1ccc2nc(SCC(=O)Nc3cccc(C)c3C)sc2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G02 compound treatment 1683607.0 -40200.0 -0.08 1318116.0 -411000.0 -0.82 -0.6339 -0.7689 3630538 CBKinase1_020522 COc1ccc(NC(=O)CCN2C(=O)c3ccccc3C2=O)c(c1)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G03 mock treatment 1878462.0 155000.0 0.29 1599761.0 -129000.0 -0.26 0.0228 0.0587 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G04 mock treatment 1778008.0 54200.0 0.1 1840822.0 112000.0 0.22 0.2302 0.9364 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G05 compound treatment 1891999.0 168000.0 0.32 1657158.0 -71700.0 -0.14 0.1219 0.3515 3630539 CBKinase1_020523 FC(F)(F)c1cccc(c1)S(=O)(=O)NCc2ccc(cc2)C(=O)Nc3ccc4OCCOc4c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G06 compound treatment 2117988.0 394000.0 0.74 1934848.0 206000.0 0.41 0.8144 0.9617 3630540 CBKinase1_020524 COC(=O)COc1cccc(NC(=O)c2cc(OC)cc(OC)c2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G07 compound treatment 2003275.0 279000.0 0.52 1652844.0 -76000.0 -0.15 0.2635 0.4824 3630541 CBKinase1_020525 O=C(CN1C(=O)CNC1=O)Nc2cccc3ccccc23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G08 compound treatment 2159058.0 435000.0 0.82 1696665.0 -32200.0 -0.06 0.5323 0.6494 3630542 CBKinase1_020526 O=C(CCN1C(=O)c2ccccc2C1=O)Nc3ccc(C#N)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G09 compound treatment 2089255.0 365000.0 0.69 2067251.0 338000.0 0.68 0.9633 1.0 3630543 CBKinase1_020527 CN(CC(=O)Nc1ccccc1C(=O)N2CCCC2)S(=O)(=O)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G10 compound treatment 2277736.0 554000.0 1.04 1748786.0 19900.0 0.04 0.7635 0.7336 3630544 CBKinase1_020528 Cc1cc(O)nc(SCCCOc2ccc3CCCc3c2)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G11 compound treatment 2363023.0 639000.0 1.2 1614117.0 -115000.0 -0.23 0.6864 0.5618 3630545 CBKinase1_020529 CCc1cc(OCCCSc2nc(C)cc(O)n2)ccc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G12 compound treatment 2327033.0 603000.0 1.13 1636829.0 -92100.0 -0.18 0.6707 0.5846 3630546 CBKinase1_020530 CN(C(=O)CSc1nnc(N)s1)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G13 compound treatment 2467150.0 743000.0 1.4 1919689.0 191000.0 0.38 1.2564 0.8685 3630547 CBKinase1_020531 CCOc1ccccc1NC(=O)CSc2nc3sc(C)c(C)c3c(=O)n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G14 compound treatment 2179065.0 455000.0 0.85 2086425.0 358000.0 0.71 1.1097 0.996 3630548 CBKinase1_020532 CN(Cc1nc(no1)c2cccc(C)c2)S(=O)(=O)c3cc(Cl)ccc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G15 compound treatment 2346012.0 622000.0 1.17 2227912.0 499000.0 1.0 1.5312 0.9969 3630549 CBKinase1_020533 COc1ccccc1OCC(=O)Nc2ccccc2C(=O)N3C(C)CCCC3C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G16 compound treatment 2358764.0 635000.0 1.19 2359357.0 630000.0 1.26 1.7339 0.9996 3630550 CBKinase1_020534 CC(=O)c1ccc(NC(=O)COc2ccccc2C(=O)Nc3sc4CCCCc4c3C#N)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G17 compound treatment 2234451.0 511000.0 0.96 2006774.0 278000.0 0.56 1.0706 0.9663 3630551 CBKinase1_020535 CC(=O)c1cccc(NC(=O)CSc2nc(cs2)c3ccc(F)cc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G18 compound treatment 2030490.0 307000.0 0.58 1976547.0 248000.0 0.49 0.7571 0.9972 3630552 CBKinase1_020536 CC(=O)c1ccc(NC(=O)COc2ccccc2C(=O)Nc3cc(ccc3Cl)C(F)(F)F)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G19 mock treatment 2025246.0 301000.0 0.57 2276697.0 548000.0 1.09 1.1744 0.9528 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G20 mock treatment 1990306.0 267000.0 0.5 1834714.0 106000.0 0.21 0.5033 0.9266 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G21 compound treatment 1581674.0 -142000.0 -0.27 1694976.0 -33900.0 -0.07 -0.2366 -0.8594 3630553 CBKinase1_020537 CC(Oc1ccc(cc1)C(C)(C)C)c2nc(no2)c3ccccn3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G22 compound treatment 1538004.0 -186000.0 -0.35 1349142.0 -380000.0 -0.76 -0.7833 -0.9378 3630554 CBKinase1_020538 CCn1c2ccccc2c3cc(NC(=O)CN(C)S(=O)(=O)c4ccc(Cl)cc4)ccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G23 compound treatment 1789394.0 65600.0 0.12 1624511.0 -104000.0 -0.21 -0.0604 -0.2495 3630555 CBKinase1_020539 COC(=O)c1cc(OC)c(OC)cc1NC(=O)CCN2C(=O)c3ccccc3C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 G24 compound treatment 1436816.0 -287000.0 -0.54 1416135.0 -313000.0 -0.63 -0.823 -0.9973 3630556 CBKinase1_020540 CN(Cc1nc(no1)c2cccc(c2)[N+](=O)[O-])S(=O)(=O)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H01 compound treatment 1358434.0 -365000.0 -0.69 1097985.0 -631000.0 -1.26 -1.3767 -0.959 3630557 CBKinase1_020541 CC(C)c1ccc(OCCCSc2nc(C)cc(O)n2)cc1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H02 compound treatment 1934131.0 210000.0 0.39 2069668.0 341000.0 0.68 0.7608 0.9664 3630558 CBKinase1_020542 Cc1ccccc1NC(=O)CSc2nnc(o2)C3(CC4CC5CC(C4)C3)C5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H03 mock treatment 1761533.0 37700.0 0.07 2094920.0 366000.0 0.73 0.5674 0.772 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H04 mock treatment 1859177.0 135000.0 0.25 2155421.0 427000.0 0.85 0.7825 0.8797 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H05 compound treatment 1924435.0 201000.0 0.38 2305836.0 577000.0 1.15 1.0817 0.8917 3630559 CBKinase1_020543 COc1cc(Cl)c(C)cc1NC(=O)CN(C)S(=O)(=O)c2ccc3ccccc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H06 compound treatment 1941840.0 218000.0 0.41 2026824.0 298000.0 0.6 0.7105 0.9833 3630560 CBKinase1_020544 Clc1cccc(NC(=O)Cn2cnc3ccccc3c2=O)c1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H07 compound treatment 326090.0 -1400000.0 -2.62 311817.0 -1420000.0 -2.83 -3.8582 -0.9993 3630561 CBKinase1_020545 Oc1c(cc(Cl)c2cccnc12)C(Nc3ccccn3)c4cccc(Cl)c4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H08 compound treatment 1785785.0 62000.0 0.12 2264324.0 535000.0 1.07 0.839 0.7794 3630562 CBKinase1_020546 COC(=O)c1cc(OC)c(OC)cc1NC(=O)COc2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H09 compound treatment 2207745.0 484000.0 0.91 2181156.0 452000.0 0.9 1.2816 1.0 3630563 CBKinase1_020547 CC(=O)Nc1ccc(NC(=O)CSc2nc3sc(C)c(C)c3c(=O)n2C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H10 compound treatment 2159167.0 435000.0 0.82 2481938.0 753000.0 1.51 1.6422 0.9588 3630564 CBKinase1_020548 COC(=O)COc1cccc(NC(=O)c2ccccc2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H11 compound treatment 2047826.0 324000.0 0.61 2277336.0 548000.0 1.1 1.2053 0.9614 3630565 CBKinase1_020549 CN(CC(=O)Nc1ccccc1C(C)(C)C)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H12 compound treatment 2674404.0 951000.0 1.78 2695052.0 966000.0 1.93 2.6274 0.9992 3630566 CBKinase1_020550 Clc1cc(NC(=O)CSc2nnc(o2)C3(CC4CC5CC(C4)C3)C5)ccc1N6CCOCC6 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H13 compound treatment 2122060.0 398000.0 0.75 2508046.0 779000.0 1.56 1.6299 0.9435 3630567 CBKinase1_020551 Cc1cc(O)nc(SCCCOc2ccc(F)cc2)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H14 compound treatment 2232173.0 508000.0 0.95 1959763.0 231000.0 0.46 1.0011 0.9444 3630568 CBKinase1_020552 O=S(=O)(N1CCOCC1)n2nnc3ccccc23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H15 compound treatment 2224711.0 501000.0 0.94 1955508.0 227000.0 0.45 0.9852 0.9439 3630569 CBKinase1_020553 COc1cc(/C=C/C)ccc1OCCSc2nc(C)cc(O)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H16 compound treatment 2183644.0 460000.0 0.86 2246442.0 518000.0 1.03 1.3419 0.996 3630571 CBKinase1_020554 Cc1nn(CC(O)COc2ccc3CCCc3c2)c(C)c1Br 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H17 compound treatment 1805035.0 81200.0 0.15 1826635.0 97700.0 0.2 0.246 0.9925 3630572 CBKinase1_020555 [O-][N+](=O)c1ccccc1OCCCn2cnc3ccccc3c2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H18 compound treatment 2203696.0 480000.0 0.9 2461581.0 733000.0 1.46 1.6726 0.9728 3630573 CBKinase1_020556 CN(C)S(=O)(=O)n1nc(C)c(CN2C(=O)c3ccccc3C2=O)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H19 mock treatment 2300621.0 577000.0 1.08 2163184.0 434000.0 0.87 1.3795 0.994 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H20 mock treatment 1882582.0 159000.0 0.3 2059336.0 330000.0 0.66 0.6778 0.9354 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H21 compound treatment 1719405.0 -4400.0 -0.01 1783385.0 54500.0 0.11 0.0712 0.6517 3630574 CBKinase1_020557 Brc1c(OCC(=O)NCc2ccco2)ccc3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H22 compound treatment 1899656.0 176000.0 0.33 1844675.0 116000.0 0.23 0.3971 0.9849 3630575 CBKinase1_020558 Fc1cccc(Cl)c1C2=NOC(C2)C(=O)Nc3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H23 compound treatment 1789353.0 65600.0 0.12 1721851.0 -7040.0 -0.01 0.0771 0.6223 3630576 CBKinase1_020559 COc1cc(/C=C/C)ccc1OCCCSc2nc(C)cc(O)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 H24 compound treatment 661478.0 -1060000.0 -1.99 726485.0 -1000000.0 -2.0 -2.8269 -1.0 3630578 CBKinase1_020560 Clc1ccc(cc1Cl)C2=NOC(C2)C(=O)NCCCN3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I01 compound treatment 1391587.0 -332000.0 -0.62 1662416.0 -66500.0 -0.13 -0.535 -0.8389 3630579 CBKinase1_020561 Cc1ccc(C)c(NC(=O)C2CN(CCN2S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I02 compound treatment 1515778.0 -208000.0 -0.39 1821865.0 93000.0 0.19 -0.1447 -0.3347 3630580 CBKinase1_020562 Cc1ccc(SCCCCSc2nc(C)cc(O)n2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I03 compound treatment 1782359.0 58600.0 0.11 1883126.0 154000.0 0.31 0.2957 0.9035 3630581 CBKinase1_020563 COc1ccccc1NC(=O)Cn2cnc3sc(cc3c2=O)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I04 compound treatment 1717604.0 -6200.0 -0.01 1719042.0 -9850.0 -0.02 -0.0221 -0.9685 3630582 CBKinase1_020564 COc1cc(/C=C/C)ccc1OCCCN2C(=O)NC(C)(C)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I05 mock treatment 1887776.0 164000.0 0.31 2029026.0 300000.0 0.6 0.6419 0.9519 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I06 mock treatment 1908443.0 185000.0 0.35 1999803.0 271000.0 0.54 0.628 0.9768 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I07 compound treatment 1904397.0 181000.0 0.34 1792526.0 63600.0 0.13 0.3297 0.9104 3630584 CBKinase1_020565 Nc1ncnc(NCC2CCCO2)c1[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I08 compound treatment 1420506.0 -303000.0 -0.57 1697088.0 -31800.0 -0.06 -0.4476 -0.7812 3630585 CBKinase1_020566 CN(CC(=O)Nc1ccc(Nc2ccccc2)cc1)S(=O)(=O)c3cc(Cl)ccc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I09 compound treatment 2002069.0 278000.0 0.52 1966846.0 238000.0 0.48 0.7057 0.9989 3630586 CBKinase1_020567 Cc1cc(O)nc(SCCCOc2ccccc2Cl)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I10 compound treatment 2272815.0 549000.0 1.03 2044997.0 316000.0 0.63 1.1756 0.9724 3630587 CBKinase1_020568 Cc1ccc(NC(=O)COc2ccc3ccccc3c2Br)c(c1)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I11 compound treatment 2199840.0 476000.0 0.89 2048856.0 320000.0 0.64 1.0841 0.9865 3630588 CBKinase1_020569 Cn1c(SCC(=O)c2ccc(Cl)cc2)nnc1c3ccccc3O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I12 compound treatment 1816908.0 93100.0 0.17 2062874.0 334000.0 0.67 0.5956 0.8632 3630589 CBKinase1_020570 CC(=O)Nc1ccccc1NC(=O)CN2C(=O)c3ccccc3C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I13 compound treatment 2332248.0 608000.0 1.14 2201932.0 473000.0 0.95 1.4762 0.9956 3630590 CBKinase1_020571 Cc1c(Cl)cccc1NC(=O)CCN2C(=O)c3ccc(cc3C2=O)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I14 compound treatment 2236136.0 512000.0 0.96 2120545.0 392000.0 0.78 1.2336 0.9948 3630591 CBKinase1_020572 Cc1cc(O)nc(SCCOc2ccc(Br)cc2Cl)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I15 compound treatment 2334222.0 610000.0 1.15 2072381.0 343000.0 0.69 1.2958 0.97 3630592 CBKinase1_020573 CN(CC(=O)Nc1ccccc1C(=O)N2CCCCC2)S(=O)(=O)c3ccc4ccccc4c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I16 compound treatment 2077111.0 353000.0 0.66 2101273.0 372000.0 0.74 0.9953 0.9983 3630593 CBKinase1_020574 Clc1cccc(NC(=O)CCN2C(=O)c3ccccc3S2(=O)=O)c1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I17 compound treatment 2044515.0 321000.0 0.6 2003873.0 275000.0 0.55 0.8144 0.999 3630594 CBKinase1_020575 OC(=O)c1ccc(CNC(=O)c2cccnc2C(=O)O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I18 compound treatment 1737406.0 13600.0 0.03 1584304.0 -145000.0 -0.29 -0.1863 -0.6421 3630595 CBKinase1_020576 COc1ccc(cc1)c2nnc(SCc3csc(N)n3)n2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I19 compound treatment 2051115.0 327000.0 0.61 2017885.0 289000.0 0.58 0.8429 0.9995 3630596 CBKinase1_020577 COc1c(C)cc(Br)cc1C(=O)NC(=S)Nc2sc3CCCCCc3c2C(=O)N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I20 compound treatment 2348608.0 625000.0 1.17 1818665.0 89800.0 0.18 0.9563 0.8059 3630597 CBKinase1_020578 CC(=O)Nc1ccc(NS(=O)(=O)c2ccc(C)cc2[N+](=O)[O-])cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I21 mock treatment 2030326.0 307000.0 0.58 1756236.0 27300.0 0.05 0.4456 0.7708 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I22 mock treatment 1961601.0 238000.0 0.45 1795256.0 66400.0 0.13 0.4095 0.8792 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I23 compound treatment 1460675.0 -263000.0 -0.49 1823801.0 94900.0 0.19 -0.2152 -0.4066 3630598 CBKinase1_020579 O=C(Cn1cnc2ccccc2c1=O)Nc3cccc(c3)C(=O)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 I24 compound treatment 1376677.0 -347000.0 -0.65 1458071.0 -271000.0 -0.54 -0.8435 -0.9957 3630599 CBKinase1_020580 [O-][N+](=O)c1cccc(c1)S(=O)(=O)Nc2cccc(c2)C(=O)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J01 compound treatment 1134017.0 -590000.0 -1.11 1336670.0 -392000.0 -0.78 -1.3372 -0.9857 3630600 CBKinase1_020581 O=C(OCc1cccc(c1)C(=O)Oc2ccccc2)c3cc4ccccc4oc3=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J02 compound treatment 1656333.0 -67500.0 -0.13 1627485.0 -101000.0 -0.2 -0.2329 -0.9744 3630601 CBKinase1_020582 CCc1ccc2NC(=O)C(O)(CC(=O)c3ccco3)c2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J03 compound treatment 1404256.0 -320000.0 -0.6 1438322.0 -291000.0 -0.58 -0.8348 -0.9999 3630602 CBKinase1_020583 Brc1c(OCC(=O)Nc2nnc[nH]2)ccc3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J04 compound treatment 419106.0 -1300000.0 -2.45 420187.0 -1310000.0 -2.62 -3.5815 -0.9995 3630603 CBKinase1_020584 Oc1c(cc(Cl)c2cccnc12)C(Nc3ccccn3)c4ccccc4F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J05 mock treatment 1721279.0 -2520.0 0.0 1652789.0 -76100.0 -0.15 -0.1109 -0.7288 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J06 mock treatment 1770791.0 47000.0 0.09 1557386.0 -172000.0 -0.34 -0.18 -0.5086 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J07 compound treatment 1784538.0 60700.0 0.11 1709283.0 -19600.0 -0.04 0.0529 0.4389 3630604 CBKinase1_020585 Cc1cc(Cl)ccc1OCC(=O)Nc2cc(Cl)ccc2C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J08 compound treatment 1502481.0 -221000.0 -0.42 1629876.0 -99000.0 -0.2 -0.4337 -0.9425 3630605 CBKinase1_020586 CN(Cc1nc(no1)c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3cc(Cl)ccc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J09 compound treatment 1677384.0 -46400.0 -0.09 1646569.0 -82300.0 -0.16 -0.178 -0.9558 3630606 CBKinase1_020587 Cc1ccc([N+](=O)[O-])c(OCCCN2C(=O)NC(C)(C)C2=O)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J10 compound treatment 2018017.0 294000.0 0.55 1655841.0 -73000.0 -0.15 0.2873 0.5029 3630607 CBKinase1_020588 CN(C(=O)CSc1nnc(c2ccc(cc2)[N+](=O)[O-])n1C)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J11 compound treatment 2101107.0 377000.0 0.71 1674758.0 -54100.0 -0.11 0.4244 0.5922 3630608 CBKinase1_020589 CC(C)(C)c1ccc(cc1)c2nnc(SCC(=O)Nc3ccccc3[N+](=O)[O-])o2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J12 compound treatment 2136970.0 413000.0 0.78 2291302.0 562000.0 1.12 1.3433 0.9836 3630609 CBKinase1_020590 CN(CC(=O)Nc1ccc(cc1)C(=O)C)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J13 compound treatment 1804383.0 80600.0 0.15 2145400.0 417000.0 0.83 0.6956 0.8221 3630610 CBKinase1_020591 Brc1c(OCC(=O)Nc2cccnc2)ccc3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J14 compound treatment 2223760.0 500000.0 0.94 1661016.0 -67900.0 -0.14 0.5678 0.5987 3630611 CBKinase1_020592 O=S(=O)(N1CCOCC1)n2c(Cc3ccccc3)nc4ccccc24 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J15 compound treatment 1970945.0 247000.0 0.46 1903510.0 175000.0 0.35 0.5749 0.9902 3630612 CBKinase1_020593 CC(=O)c1cccc(NC(=O)COc2ccccc2C(=O)Nc3ccc4c(c3)oc5ccccc54)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J16 compound treatment 2233490.0 510000.0 0.96 1964524.0 236000.0 0.47 1.0096 0.9467 3630613 CBKinase1_020594 CC(=O)Nc1ccc(OCC(O)Cn2nc(C)cc2C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J17 compound treatment 298104.0 -1430000.0 -2.68 275195.0 -1450000.0 -2.91 -3.9471 -0.9992 3630614 CBKinase1_020595 Oc1c(cc(Cl)c2cccnc12)C(Nc3ccccn3)c4cccc(c4)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J18 compound treatment 1771012.0 47200.0 0.09 1884440.0 156000.0 0.31 0.2825 0.8739 3630615 CBKinase1_020596 COC(=O)C(O)(c1c(C)nn(c1N)c2ccccc2)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J19 compound treatment 1966743.0 243000.0 0.46 1919329.0 190000.0 0.38 0.5916 0.996 3630616 CBKinase1_020597 OC(=O)c1ccc(CNC(=O)c2ccc(NC(=O)c3ccco3)cc2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J20 compound treatment 1553979.0 -170000.0 -0.32 1225932.0 -503000.0 -1.01 -0.9363 -0.8878 3630617 CBKinase1_020598 COc1cc(cc(OC)c1OC)C(=O)NC2(C(=O)N(CC3CCCO3)C4=C2C(=O)CC(C)(C)C4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J21 mock treatment 1633005.0 -90800.0 -0.17 1567085.0 -162000.0 -0.32 -0.3492 -0.9552 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J22 mock treatment 1662084.0 -61700.0 -0.12 1989093.0 260000.0 0.52 0.2858 0.5364 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J23 compound treatment 1414351.0 -309000.0 -0.58 1233972.0 -495000.0 -0.99 -1.1102 -0.9678 3630618 CBKinase1_020599 Cc1ccc(c2nnc(SCC(=O)Nc3ccccc3Cl)n2C)c(Cl)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 J24 compound treatment 1212317.0 -511000.0 -0.96 1127363.0 -602000.0 -1.2 -1.5291 -0.9938 3630619 CBKinase1_020600 Clc1ccc(cc1Cl)C2=NOC(C2)C(=O)NCc3ccccn3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K01 compound treatment 1315291.0 -409000.0 -0.77 1431440.0 -297000.0 -0.59 -0.9627 -0.9921 3630620 CBKinase1_020601 Clc1ccc(NC(=O)CC2NC(=O)NC2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K02 compound treatment 1348955.0 -375000.0 -0.7 1550231.0 -179000.0 -0.36 -0.7501 -0.9505 3630621 CBKinase1_020602 Fc1ccc(NC(=O)c2ccccc2NC(=O)COc3ccc4ccccc4c3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K03 compound treatment 1236019.0 -488000.0 -0.92 1293018.0 -436000.0 -0.87 -1.2635 -0.9997 3630622 CBKinase1_020603 CN(C)CCCNc1ncnc(N)c1[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K04 compound treatment 931231.0 -793000.0 -1.49 1307707.0 -421000.0 -0.84 -1.6474 -0.9636 3630623 CBKinase1_020604 CC(Oc1ccc(cc1)C(C)(C)C)c2nc(no2)c3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K05 compound treatment 1511467.0 -212000.0 -0.4 1445061.0 -284000.0 -0.57 -0.683 -0.9851 3630624 CBKinase1_020605 Cc1cc(C(=O)CSc2nc[nH]n2)c(C)n1c3cc(F)ccc3F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K06 compound treatment 1544152.0 -180000.0 -0.34 1506904.0 -222000.0 -0.44 -0.5522 -0.9908 3630625 CBKinase1_020606 O=C(OCc1cccc(c1)C(=O)Oc2ccccc2)c3cnccn3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K07 mock treatment 1591356.0 -132000.0 -0.25 1298041.0 -431000.0 -0.86 -0.7847 -0.8755 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K08 mock treatment 1162942.0 -561000.0 -1.05 1586321.0 -143000.0 -0.28 -0.946 -0.8673 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K09 compound treatment 1629640.0 -94200.0 -0.18 1470287.0 -259000.0 -0.52 -0.4905 -0.8979 3630626 CBKinase1_020607 CN(CC(=O)Nc1cccc2CCCCc12)S(=O)(=O)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K10 compound treatment 1465944.0 -258000.0 -0.48 1379410.0 -349000.0 -0.7 -0.8362 -0.984 3630627 CBKinase1_020608 COc1cc2c(cc1NC(=O)CN(C)S(=O)(=O)c3ccc(Cl)cc3)oc4ccccc42 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K11 compound treatment 1771254.0 47500.0 0.09 1661288.0 -67600.0 -0.14 -0.0325 -0.2011 3630628 CBKinase1_020609 O=C(Nc1cccc(c1)c2nc3cc(ccc3[nH]2)C(=O)c4ccccc4)C5CCCO5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K12 compound treatment 1710214.0 -13600.0 -0.03 1755413.0 26500.0 0.05 0.0195 0.3306 3630629 CBKinase1_020610 Cc1cc(Cl)ccc1OCC(=O)Nc2ccc(Br)cc2C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K13 compound treatment 1806750.0 82900.0 0.16 1682025.0 -46900.0 -0.09 0.0439 0.2415 3630630 CBKinase1_020611 Cc1ccc(c2nnc(SCC(=O)Nc3ccc4c(c3)oc5ccccc54)n2C)c(Cl)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K14 compound treatment 1944380.0 221000.0 0.41 1877205.0 148000.0 0.3 0.5024 0.9866 3630631 CBKinase1_020612 Cc1cc(O)nc(SCCOc2cccc(Br)c2)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K15 mock treatment 2061155.0 337000.0 0.63 1857593.0 129000.0 0.26 0.6297 0.9212 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K16 mock treatment 1845161.0 121000.0 0.23 1763264.0 34400.0 0.07 0.2097 0.8812 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K17 compound treatment 1814341.0 90500.0 0.17 1821551.0 92700.0 0.19 0.2512 0.9991 3630632 CBKinase1_020613 COc1ccc(cc1)C(=O)CSc2nnc(CC(C)O)n2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K18 compound treatment 1649459.0 -74300.0 -0.14 1738335.0 9450.0 0.02 -0.0853 -0.6059 3630633 CBKinase1_020614 Cc1nn(c(C)c1NC(=O)COc2ccc3ccccc3c2)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K19 compound treatment 1873108.0 149000.0 0.28 1722523.0 -6360.0 -0.01 0.1892 0.6743 3630634 CBKinase1_020615 CN(CC(=O)Nc1cccnc1)S(=O)(=O)c2ccc3ccccc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K20 compound treatment 1750577.0 26800.0 0.05 1350226.0 -379000.0 -0.76 -0.4996 -0.6587 3630635 CBKinase1_020616 Brc1c(OCC(=O)NCc2cccnc2)ccc3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K21 compound treatment 1572754.0 -151000.0 -0.28 1622180.0 -107000.0 -0.21 -0.3513 -0.9901 3630636 CBKinase1_020617 COc1cc(NC(=O)COc2ccc3ccccc3c2Br)c(OC)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K22 compound treatment 1077846.0 -646000.0 -1.21 1131616.0 -597000.0 -1.19 -1.7016 -1.0 3630637 CBKinase1_020618 COC(=O)c1cc(OC)c(OC)cc1NC(=O)COc2ccc3ccccc3c2Br 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K23 mock treatment 1008920.0 -715000.0 -1.34 1278641.0 -450000.0 -0.9 -1.5853 -0.9811 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 K24 mock treatment 1293741.0 -430000.0 -0.81 696098.0 -1030000.0 -2.06 -2.0305 -0.9161 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L01 compound treatment 1163727.0 -560000.0 -1.05 1235376.0 -494000.0 -0.99 -1.441 -0.9995 3630638 CBKinase1_020619 Fc1ccc(NC(=O)CCn2cnc3ccccc3c2=O)cc1C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L02 compound treatment 1179356.0 -544000.0 -1.02 1311753.0 -417000.0 -0.83 -1.3123 -0.9949 3630639 CBKinase1_020620 CS(=O)(=O)CCC(N1C(=O)c2ccc(Br)cc2C1=O)C(=O)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L03 compound treatment 1070874.0 -653000.0 -1.23 1492123.0 -237000.0 -0.47 -1.2014 -0.9143 3630640 CBKinase1_020621 CN(Cc1nc(no1)c2ccccn2)S(=O)(=O)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L04 compound treatment 1088203.0 -636000.0 -1.19 1218514.0 -510000.0 -1.02 -1.565 -0.997 3630641 CBKinase1_020622 Cc1ccc(NC(=O)CSCc2n[nH]c(=O)[nH]2)c(Br)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L05 compound treatment 1152278.0 -572000.0 -1.07 1168059.0 -561000.0 -1.12 -1.5513 -0.9998 3630642 CBKinase1_020623 CN1C(=O)C(O)(CC(=O)c2ccco2)c3cccc(C)c13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L06 compound treatment 1435084.0 -289000.0 -0.54 1440695.0 -288000.0 -0.58 -0.7906 -0.9995 3630643 CBKinase1_020624 Cc1ccc(NC(=O)CSc2nnc(c3ccc(C)c(Cl)c3)n2C)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L07 mock treatment 1428793.0 -295000.0 -0.55 1521172.0 -208000.0 -0.42 -0.6852 -0.9899 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L08 mock treatment 1452282.0 -272000.0 -0.51 1220681.0 -508000.0 -1.02 -1.0787 -0.9491 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L09 compound treatment 1032479.0 -691000.0 -1.3 1424871.0 -304000.0 -0.61 -1.3474 -0.9402 3630644 CBKinase1_020625 CN(CC(=O)Nc1ccccc1NC(=O)C)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L10 compound treatment 1733508.0 9710.0 0.02 1791449.0 62600.0 0.13 0.1013 0.8017 3630645 CBKinase1_020626 CCOc1cccc(c1)c2nnc(SCC(=O)Nc3cccc(Cl)c3C)n2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L11 compound treatment 1439457.0 -284000.0 -0.53 1477614.0 -251000.0 -0.5 -0.7326 -0.9995 3630646 CBKinase1_020627 OC1(CC(=O)c2ccc3CCCCc3c2)C(=O)N(CCOc4ccccc4)c5ccccc51 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L12 compound treatment 1425358.0 -298000.0 -0.56 1430800.0 -298000.0 -0.6 -0.8175 -0.9995 3630647 CBKinase1_020628 COC(=O)C1=C(C)n2nnnc2NC1c3cc4ccccc4o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L13 compound treatment 1746508.0 22700.0 0.04 1545944.0 -183000.0 -0.37 -0.2284 -0.6205 3630648 CBKinase1_020629 FC(F)(F)c1ccccc1NC(=O)CSc2nc(cs2)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L14 compound treatment 1583464.0 -140000.0 -0.26 1640475.0 -88400.0 -0.18 -0.3112 -0.9811 3630649 CBKinase1_020630 Cc1nc(C)n(CC(O)COc2ccc3CCCc3c2)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L15 mock treatment 1795866.0 72100.0 0.14 1788117.0 59200.0 0.12 0.1794 0.9978 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L16 mock treatment 1447891.0 -276000.0 -0.52 1563917.0 -165000.0 -0.33 -0.5994 -0.9762 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L17 compound treatment 1763155.0 39400.0 0.07 926020.0 -803000.0 -1.6 -1.0824 -0.6738 3630650 CBKinase1_020631 Cc1cc(O)nc(SCCOc2cccc(Cl)c2)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L18 compound treatment 1602677.0 -121000.0 -0.23 1396797.0 -332000.0 -0.66 -0.6301 -0.8981 3630651 CBKinase1_020632 Cc1ccc(cc1)S(=O)(=O)NC2(C(=O)N(CC3CCCO3)C4=C2C(=O)CC(C)(C)C4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L19 compound treatment 1349390.0 -374000.0 -0.7 1420247.0 -309000.0 -0.62 -0.9332 -0.9979 3630652 CBKinase1_020633 CCc1cc(OCCSc2nc(C)cc(O)n2)ccc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L20 compound treatment 1461701.0 -262000.0 -0.49 1451943.0 -277000.0 -0.55 -0.7393 -0.9983 3630653 CBKinase1_020634 COc1ccc(cc1)S(=O)(=O)NC2(C(=O)N(Cc3cccnc3)C4=C2C(=O)CC(C)(C)C4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L21 compound treatment 1403666.0 -320000.0 -0.6 1192182.0 -537000.0 -1.07 -1.1835 -0.9625 3630654 CBKinase1_020635 CC(C)c1ccc(NC(=O)CCN2C(=O)c3ccc(cc3C2=O)[N+](=O)[O-])cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L22 compound treatment 1594279.0 -130000.0 -0.24 1294994.0 -434000.0 -0.87 -0.7852 -0.8718 3630655 CBKinase1_020636 Cc1cc(NC(=O)C2CC(=NO2)c3c(F)cccc3Cl)n(n1)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L23 mock treatment 1370246.0 -354000.0 -0.66 1268778.0 -460000.0 -0.92 -1.1196 -0.9872 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 L24 mock treatment 1289654.0 -434000.0 -0.82 1051254.0 -678000.0 -1.35 -1.534 -0.9705 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M01 compound treatment 1325348.0 -398000.0 -0.75 1136883.0 -592000.0 -1.18 -1.3656 -0.9755 3630656 CBKinase1_020637 Clc1cc(Cl)cc(NC(=O)CSc2ncccn2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M02 compound treatment 1577360.0 -146000.0 -0.27 1852088.0 123000.0 0.25 -0.0203 -0.0549 3630657 CBKinase1_020638 CN(CC(=O)Nc1ccc(Cl)cc1C(=O)c2ccccc2)S(=O)(=O)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M03 compound treatment 1540139.0 -184000.0 -0.34 1590345.0 -139000.0 -0.28 -0.4396 -0.9941 3630658 CBKinase1_020639 Cc1ccc(cc1)C(=O)Oc2ccc(cc2)C(=O)CSc3nc4ccccc4o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M04 compound treatment 1528118.0 -196000.0 -0.37 1265840.0 -463000.0 -0.93 -0.9142 -0.9181 3630659 CBKinase1_020640 CC(Oc1ccc(cc1)C(C)(C)C)C(=O)NCc2ccco2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M05 compound treatment 1663403.0 -60400.0 -0.11 1479536.0 -249000.0 -0.5 -0.4326 -0.8464 3630660 CBKinase1_020641 CC(C)C(NS(=O)(=O)c1c(Cl)cccc1Cl)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M06 compound treatment 1961388.0 238000.0 0.45 1441173.0 -288000.0 -0.58 -0.0912 -0.1254 3630661 CBKinase1_020642 COc1cc(OC)cc(c1)C(=O)Nc2ccc(OCC(=O)O)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M07 compound treatment 1686308.0 -37500.0 -0.07 1517554.0 -211000.0 -0.42 -0.3484 -0.8137 3630662 CBKinase1_020643 O=C(CSc1nc[nH]n1)c2ccc3OCCOc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M08 compound treatment 1254853.0 -469000.0 -0.88 1402989.0 -326000.0 -0.65 -1.0831 -0.989 3630663 CBKinase1_020644 Cn1c(SCC(=O)Nc2ccccc2)nc3sc4CCCc4c3c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M09 mock treatment 1772303.0 48500.0 0.09 1418176.0 -311000.0 -0.62 -0.3747 -0.597 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M10 mock treatment 1759061.0 35300.0 0.07 1401367.0 -328000.0 -0.65 -0.4161 -0.6324 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M11 compound treatment 1620028.0 -104000.0 -0.19 1235396.0 -493000.0 -0.99 -0.8352 -0.8307 3630664 CBKinase1_020645 COC(=O)c1cc(OC)c(OC)cc1NC(=O)C(C)Oc2ccc(cc2)C(C)(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M12 compound treatment 1752346.0 28500.0 0.05 1589389.0 -139000.0 -0.28 -0.1593 -0.5609 3630665 CBKinase1_020646 OC(=O)C(NC(=O)Nc1ccc(Cl)cc1)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M13 mock treatment 1895023.0 171000.0 0.32 1559536.0 -169000.0 -0.34 -0.012 -0.0258 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M14 mock treatment 1805724.0 81900.0 0.15 1632791.0 -96100.0 -0.19 -0.0271 -0.11 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M15 compound treatment 1705174.0 -18600.0 -0.03 1497490.0 -231000.0 -0.46 -0.3518 -0.7584 3630666 CBKinase1_020647 CN(CC(=O)Nc1ccccc1C#N)S(=O)(=O)c2ccc3ccccc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M16 compound treatment 1914107.0 190000.0 0.36 1595336.0 -134000.0 -0.27 0.0639 0.1432 3630667 CBKinase1_020648 COc1ccc(NC(=O)c2cccnc2C(=O)O)c(OC)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M17 compound treatment 1881960.0 158000.0 0.3 1472682.0 -256000.0 -0.51 -0.1521 -0.257 3630668 CBKinase1_020649 Cc1c2NC(=O)C(O)(CC(=O)c3ccco3)c2ccc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M18 compound treatment 1841461.0 118000.0 0.22 1512093.0 -217000.0 -0.43 -0.1502 -0.3088 3630669 CBKinase1_020650 CC1(C)NC(=O)N(CCCOc2ccccc2CO)C1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M19 compound treatment 1929296.0 205000.0 0.39 1623836.0 -105000.0 -0.21 0.1243 0.2831 3630670 CBKinase1_020651 CCc1ccccc1NC(=O)CSc2nc3sc4CCCc4c3c(=O)n2c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M20 compound treatment 2053771.0 330000.0 0.62 1622848.0 -106000.0 -0.21 0.2882 0.4401 3630671 CBKinase1_020652 CC(=O)Nc1ccccc1NC(=O)CCN2C(=O)c3ccccc3C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M21 compound treatment 1931246.0 207000.0 0.39 1697132.0 -31800.0 -0.06 0.2305 0.5842 3630672 CBKinase1_020653 CCS(=O)(=O)c1ccc2nc(SCC(=O)n3c4CCCCc4c5ccccc35)oc2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M22 compound treatment 629088.0 -1090000.0 -2.06 612936.0 -1120000.0 -2.23 -3.0304 -0.9992 3630673 CBKinase1_020654 COc1ccccc1NC(=O)CSc2nnc(c3cccc4ccccc34)n2c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M23 compound treatment 888354.0 -835000.0 -1.57 634209.0 -1090000.0 -2.19 -2.6561 -0.9867 3630674 CBKinase1_020655 OCCCc1nnc(Sc2ccc(cc2[N+](=O)[O-])C(F)(F)F)n1c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 M24 compound treatment 1179825.0 -544000.0 -1.02 819829.0 -909000.0 -1.82 -2.0069 -0.9629 3630675 CBKinase1_020656 COc1cccc(c1)C(=O)Nc2cc(C)ccc2NC(=O)COc3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N01 compound treatment 1214019.0 -510000.0 -0.96 1104538.0 -624000.0 -1.25 -1.5591 -0.9914 3630676 CBKinase1_020657 CN(CC(=O)Nc1nnc[nH]1)S(=O)(=O)c2ccc3ccccc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N02 compound treatment 1533910.0 -190000.0 -0.36 1427570.0 -301000.0 -0.6 -0.6779 -0.9687 3630677 CBKinase1_020658 COc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(c3)C(=O)C)n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N03 compound treatment 1621812.0 -102000.0 -0.19 2428663.0 700000.0 1.4 0.8536 0.6047 3630678 CBKinase1_020659 COc1ccc(cc1OC)c2noc(CN(C)S(=O)(=O)c3ccc(Cl)cc3)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N04 compound treatment 1658147.0 -65700.0 -0.12 1678414.0 -50500.0 -0.1 -0.1585 -0.9951 3630679 CBKinase1_020660 COC(=O)c1ccccc1NC(=O)c2ccc(NC(=O)CSc3ccccc3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N05 compound treatment 1462037.0 -262000.0 -0.49 1435785.0 -293000.0 -0.59 -0.7617 -0.9962 3630680 CBKinase1_020661 Cc1cc(O)nc(SCCOc2ccc(F)cc2)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N06 compound treatment 1681621.0 -42200.0 -0.08 1285511.0 -443000.0 -0.89 -0.6826 -0.7672 3630681 CBKinase1_020662 CCN1C(=O)C(O)(CC(=O)c2ccco2)c3cc(Br)ccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N07 compound treatment 1706025.0 -17800.0 -0.03 1689550.0 -39300.0 -0.08 -0.0792 -0.9272 3630682 CBKinase1_020663 CC(=O)Nc1ccccc1NC(=O)COc2ccc3ccccc3c2Br 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N08 compound treatment 1457086.0 -267000.0 -0.5 1653807.0 -75100.0 -0.15 -0.4602 -0.8803 3630683 CBKinase1_020664 COc1ccc(NC(=O)COc2ccc(Cl)cc2)cc1NC(=O)c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N09 mock treatment 1713873.0 -9930.0 -0.02 1765223.0 36300.0 0.07 0.0382 0.5091 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N10 mock treatment 1807952.0 84200.0 0.16 1569729.0 -159000.0 -0.32 -0.1132 -0.3188 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N11 compound treatment 1831248.0 107000.0 0.2 1674966.0 -53900.0 -0.11 0.0664 0.2905 3630684 CBKinase1_020665 Fc1ccc(cc1)C(=O)CSc2nnc(c3cccc(Br)c3)n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N12 compound treatment 1447796.0 -276000.0 -0.52 1597014.0 -132000.0 -0.26 -0.5528 -0.9508 3630685 CBKinase1_020666 CN1C(=O)C(O)(CC(=O)c2ccco2)c3cc(C)cc(Br)c13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N13 mock treatment 1634848.0 -89000.0 -0.17 1686183.0 -42700.0 -0.09 -0.1784 -0.9514 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N14 mock treatment 1853804.0 130000.0 0.24 1683719.0 -45200.0 -0.09 0.1087 0.4179 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N15 compound treatment 1315215.0 -409000.0 -0.77 1159282.0 -570000.0 -1.14 -1.3474 -0.9815 3630686 CBKinase1_020667 OC1(CC(=O)c2ccco2)C(=O)Nc3ccc(F)cc31 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N16 compound treatment 1982421.0 259000.0 0.49 1671944.0 -56900.0 -0.11 0.2628 0.5271 3630687 CBKinase1_020668 CC(=O)Nc1ccc(OCC(O)Cn2nc(C)c(Br)c2C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N17 compound treatment 1939781.0 216000.0 0.41 1691214.0 -37700.0 -0.08 0.2335 0.5661 3630688 CBKinase1_020669 COC(=O)COc1cccc(NC(=O)c2ccccc2c3ccccc3C(=O)O)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N18 compound treatment 1821905.0 98100.0 0.18 1608596.0 -120000.0 -0.24 -0.0398 -0.1313 3630689 CBKinase1_020670 Cc1ccc(cc1)S(=O)(=O)NC2(C(=O)N(Cc3ccco3)C4=C2C(=O)CC(C)(C)C4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N19 compound treatment 2131788.0 408000.0 0.77 1728204.0 -683.0 0.0 0.5406 0.7058 3630690 CBKinase1_020671 Cc1ccc(cc1C)C(=O)Nc2ccc(OCC(=O)O)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N20 compound treatment 2257103.0 533000.0 1.0 1779591.0 50700.0 0.1 0.7796 0.7747 3630691 CBKinase1_020672 CC1(C)CC2=C(C(=O)C1)C(NC(=O)c3ccco3)(C(=O)N2Cc4cccnc4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N21 compound treatment 2032973.0 309000.0 0.58 1846237.0 117000.0 0.23 0.5763 0.9205 3630692 CBKinase1_020673 [O-][N+](=O)c1cccc(c1)C(=O)Nc2cccc(OCC(=O)N3CCOCC3)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N22 compound treatment 1772504.0 48700.0 0.09 1342971.0 -386000.0 -0.77 -0.4808 -0.619 3630693 CBKinase1_020674 Cc1nn(Cc2ccc(F)cc2)c(C)c1NC(=O)C3CC(=NO3)c4c(F)cccc4Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N23 compound treatment 1495891.0 -228000.0 -0.43 1301548.0 -427000.0 -0.85 -0.9065 -0.9489 3630694 CBKinase1_020675 COc1ccc(cc1)c2nnc(SCC(=O)n3c4CCCCc4c5CCCCc53)n2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 N24 compound treatment 1360785.0 -363000.0 -0.68 1160833.0 -568000.0 -1.14 -1.2847 -0.9702 3630695 CBKinase1_020676 Clc1ccc(cc1Cl)C2=NOC(C2)C(=O)Nc3cnn(c3)C4(CC5CC6CC(C5)C4)C6 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O01 compound treatment 962282.0 -762000.0 -1.43 807729.0 -921000.0 -1.84 -2.3128 -0.9922 3630696 CBKinase1_020677 Clc1ccc(c2nnc(SCC(=O)N3CCc4ccccc34)[nH]2)c(Cl)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O02 compound treatment 1046589.0 -677000.0 -1.27 887851.0 -841000.0 -1.68 -2.0876 -0.9905 3630697 CBKinase1_020678 OC(=O)Cc1ccc(NC(=O)c2cccnc2C(=O)O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O03 compound treatment 1329176.0 -395000.0 -0.74 991008.0 -738000.0 -1.47 -1.5667 -0.9493 3630698 CBKinase1_020679 COc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3cc(Cl)cc(Cl)c3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O04 compound treatment 1422428.0 -301000.0 -0.57 1117160.0 -612000.0 -1.22 -1.2646 -0.9387 3630699 CBKinase1_020680 COc1cc(NC(=O)CN(C)S(=O)(=O)c2ccc3ccccc3c2)c(OC)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O05 compound treatment 1075873.0 -648000.0 -1.22 1137030.0 -592000.0 -1.18 -1.6966 -0.9999 3630700 CBKinase1_020681 CCOC(=O)c1c(C)c(C)sc1NC(=O)C2(C)Cc3ccccc3C(=O)O2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O06 compound treatment 1039523.0 -684000.0 -1.28 1002194.0 -727000.0 -1.45 -1.9354 -0.9981 3630701 CBKinase1_020682 Cc1ccc(SCC(=O)Nc2cccc(Oc3ccc4C(=O)NC(=O)c4c3)c2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O07 compound treatment 1091980.0 -632000.0 -1.19 1035328.0 -694000.0 -1.39 -1.8189 -0.997 3630702 CBKinase1_020683 Cc1ccc(cc1)c2csc3ncnc(SCC(=O)c4ccc5OCCOc5c4)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O08 compound treatment 1151172.0 -573000.0 -1.08 1001932.0 -727000.0 -1.45 -1.7875 -0.989 3630703 CBKinase1_020684 Cc1cc(O)nc(SCCOc2ccccc2CO)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O09 compound treatment 1072801.0 -651000.0 -1.22 1406228.0 -323000.0 -0.64 -1.3202 -0.9554 3630704 CBKinase1_020685 Cn1c(NC(=O)CSc2nc3sc4CCCc4c3c(=O)n2C)cc(=O)n(C)c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O10 compound treatment 1250741.0 -473000.0 -0.89 1002564.0 -726000.0 -1.45 -1.6545 -0.9722 3630705 CBKinase1_020686 COc1cccc(OCC(=O)Nc2cccc(Oc3ccc4C(=O)NC(=O)c4c3)c2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O11 mock treatment 1095776.0 -628000.0 -1.18 1242552.0 -486000.0 -0.97 -1.521 -0.9954 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O12 mock treatment 1054675.0 -669000.0 -1.26 1323397.0 -405000.0 -0.81 -1.4613 -0.9775 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O13 compound treatment 1089117.0 -635000.0 -1.19 1050419.0 -678000.0 -1.36 -1.8014 -0.9979 3630706 CBKinase1_020687 COC(=O)c1cc(OC)c(OC)cc1NC(=O)CN2C(=O)c3ccccc3C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O14 compound treatment 1268184.0 -456000.0 -0.86 1470432.0 -258000.0 -0.52 -0.9701 -0.9708 3630707 CBKinase1_020688 Cc1cc(O)nc(SCCOc2ccccc2C#N)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O15 compound treatment 1044055.0 -680000.0 -1.28 1061440.0 -667000.0 -1.33 -1.8456 -0.9998 3630708 CBKinase1_020689 COC(=O)COc1cccc(NC(=O)c2ccc(NC(=O)c3ccco3)cc2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O16 compound treatment 1300873.0 -423000.0 -0.79 1178355.0 -551000.0 -1.1 -1.3395 -0.9872 3630709 CBKinase1_020690 CCC(=O)c1ccccc1OCCSc2nc(C)cc(O)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O17 compound treatment 1127446.0 -596000.0 -1.12 1279778.0 -449000.0 -0.9 -1.4264 -0.994 3630710 CBKinase1_020691 CC(=O)c1ccc(NC(=O)CCn2cnc3ccccc3c2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O18 compound treatment 1459656.0 -264000.0 -0.5 996767.0 -732000.0 -1.46 -1.3853 -0.8966 3630711 CBKinase1_020692 Cc1cc(O)nc(SCCOc2ccc(cc2)C(=O)c3ccccc3)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O19 compound treatment 1503808.0 -220000.0 -0.41 410724.0 -1320000.0 -2.63 -2.155 -0.8081 3630712 CBKinase1_020693 Oc1c(cc(Cl)c2cccnc12)C(Nc3ccccn3)c4ccco4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O20 compound treatment 1300135.0 -424000.0 -0.8 1133362.0 -596000.0 -1.19 -1.4041 -0.9808 3630713 CBKinase1_020694 CN(Cc1nc(no1)c2cccnc2)S(=O)(=O)c3ccc4ccccc4c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O21 compound treatment 1009357.0 -714000.0 -1.34 1269098.0 -460000.0 -0.92 -1.5982 -0.983 3630714 CBKinase1_020695 COc1cc(NC(=O)CCN2C(=O)c3ccccc3C2=O)cc(OC)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O22 compound treatment 1294497.0 -429000.0 -0.81 1358379.0 -371000.0 -0.74 -1.0935 -0.9991 3630715 CBKinase1_020696 OC(=O)C(Cc1ccc(O)cc1)NC(=O)Nc2ccc(Cl)cc2Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O23 compound treatment 958923.0 -765000.0 -1.44 1012246.0 -717000.0 -1.43 -2.0282 -1.0 3630716 CBKinase1_020697 Cc1ccc(C)c(NC(=O)CCn2cnc3ccccc3c2=O)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 O24 compound treatment 929601.0 -794000.0 -1.49 919366.0 -810000.0 -1.62 -2.1984 -0.9992 3630717 CBKinase1_020698 Clc1ccccc1NC(=O)CSc2nnc(Nc3ccccc3)n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P01 compound treatment 651346.0 -1070000.0 -2.01 850865.0 -878000.0 -1.75 -2.6646 -0.9977 3630718 CBKinase1_020699 OC1(CC(=O)c2ccccn2)C(=O)N(C/C=C/c3ccccc3)c4ccccc41 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P02 compound treatment 884950.0 -839000.0 -1.57 873482.0 -855000.0 -1.71 -2.3225 -0.9992 3630720 CBKinase1_020700 CN(CC(=O)Nc1ccc(Br)cc1C)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P03 compound treatment 828856.0 -895000.0 -1.68 802867.0 -926000.0 -1.85 -2.4968 -0.9988 3630721 CBKinase1_020701 CC(C)N(Cc1nc(no1)c2ccc(Cl)cc2)S(=O)(=O)c3ccc4ccccc4c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P04 compound treatment 929704.0 -794000.0 -1.49 904849.0 -824000.0 -1.65 -2.2187 -0.9988 3630722 CBKinase1_020702 O=C(Cn1cnc2ccccc2c1=O)Nc3ccc4c(c3)oc5ccccc54 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P05 compound treatment 872840.0 -851000.0 -1.6 1120163.0 -609000.0 -1.22 -1.9899 -0.991 3630723 CBKinase1_020703 CN1C(=O)C(O)(CC(=O)c2ccco2)c3cc(ccc13)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P06 compound treatment 974803.0 -749000.0 -1.41 924402.0 -804000.0 -1.61 -2.1312 -0.9978 3630724 CBKinase1_020704 O=C1N(CCc2nc(no2)c3ccccn3)C(=O)c4ccccc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P07 compound treatment 1025983.0 -698000.0 -1.31 962132.0 -767000.0 -1.53 -2.01 -0.997 3630725 CBKinase1_020705 [O-][N+](=O)c1ccccc1NC(=O)CSc2nnc(c3cccc(Br)c3)n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P08 compound treatment 900535.0 -823000.0 -1.55 1009328.0 -720000.0 -1.44 -2.1098 -0.9994 3630726 CBKinase1_020706 Cc1cc(Br)cc2c1NC(=O)C2(O)CC(=O)c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P09 compound treatment 1044194.0 -680000.0 -1.28 984959.0 -744000.0 -1.49 -1.9535 -0.9971 3630727 CBKinase1_020707 Cc1occc1c2nnc(SCC(=O)Nc3ccccc3[N+](=O)[O-])n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P10 compound treatment 1026250.0 -698000.0 -1.31 917585.0 -811000.0 -1.62 -2.0726 -0.9944 3630728 CBKinase1_020708 COc1ccc(OC)c(NC(=O)CSc2nc(cs2)c3ccccc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P11 mock treatment 938935.0 -785000.0 -1.47 1052911.0 -676000.0 -1.35 -1.9972 -0.9991 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P12 mock treatment 1027793.0 -696000.0 -1.31 1170953.0 -558000.0 -1.12 -1.7125 -0.9969 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P13 compound treatment 988507.0 -735000.0 -1.38 985846.0 -743000.0 -1.49 -2.0262 -0.9993 3630729 CBKinase1_020709 CN(Cc1nc(no1)c2ccncc2)S(=O)(=O)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P14 compound treatment 961700.0 -762000.0 -1.43 867060.0 -862000.0 -1.72 -2.2297 -0.9957 3630730 CBKinase1_020710 OC(COc1ccc2CCCc2c1)CN3CCN(CC3)S(=O)(=O)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P15 compound treatment 1129168.0 -595000.0 -1.12 1140988.0 -588000.0 -1.18 -1.6202 -0.9997 3630731 CBKinase1_020711 Fc1ccc(cc1)c2csc(SCC(=O)Nc3ccc(N4CCOCC4)c(Cl)c3)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P16 compound treatment 877510.0 -846000.0 -1.59 974216.0 -755000.0 -1.51 -2.19 -0.9997 3630732 CBKinase1_020712 CC(=O)Nc1ccc(OCC(O)Cn2nc(C)c(C(=O)C)c2C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P17 compound treatment 1095279.0 -629000.0 -1.18 1186791.0 -542000.0 -1.08 -1.6005 -0.9991 3630733 CBKinase1_020713 CCn1c2ccccc2c3cc(NC(=O)CCN4C(=O)c5ccccc5C4=O)ccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P18 compound treatment 943880.0 -780000.0 -1.46 890711.0 -838000.0 -1.68 -2.2199 -0.9977 3630734 CBKinase1_020714 CC1(C)CC2=C(C(=O)C1)C(NC(=O)c3cccnc3)(C(=O)N2c4ccccc4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P19 compound treatment 1153535.0 -570000.0 -1.07 1026382.0 -703000.0 -1.4 -1.7499 -0.991 3630735 CBKinase1_020715 COc1ccccc1NC(=O)c2ccccc2NC(=O)CCc3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P20 compound treatment 890833.0 -833000.0 -1.56 1013212.0 -716000.0 -1.43 -2.1172 -0.999 3630736 CBKinase1_020716 CC1(C)CC2=C(C(=O)C1)C(NC(=O)c3cccs3)(C(=O)N2Cc4cccnc4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P21 compound treatment 1275298.0 -449000.0 -0.84 1273647.0 -455000.0 -0.91 -1.2388 -0.9992 3630737 CBKinase1_020717 Cc1cc(O)nc(SCCCOc2ccccc2c3ccccc3)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P22 compound treatment 946924.0 -777000.0 -1.46 1097949.0 -631000.0 -1.26 -1.923 -0.9974 3630738 CBKinase1_020718 COC(=O)c1ccccc1NC(=O)C2CC(=NO2)c3ccc(Cl)c(Cl)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P23 compound treatment 880754.0 -843000.0 -1.58 929805.0 -799000.0 -1.6 -2.2485 -1.0 3630739 CBKinase1_020719 Cc1ccc(NC(=O)CSc2nnc(c3ccco3)n2C)c(Br)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2388 P24 compound treatment 730085.0 -994000.0 -1.87 1109091.0 -620000.0 -1.24 -2.1951 -0.9802 3630740 CBKinase1_020720 Cn1ncc(C#N)c1NC(=O)C2CC(=NO2)c3ccc(Cl)c(Cl)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A01 compound treatment 1148738.0 -467000.0 -0.88 1225436.0 -816000.0 -1.63 -1.7733 -0.9576 3631621 CBKinase1_021681 CCc1ccc(NC(=O)Cn2c(nc3ccccc23)c4nonc4N)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A02 compound treatment 1212929.0 -403000.0 -0.76 1665882.0 -376000.0 -0.75 -1.0657 -1.0 3631622 CBKinase1_021682 O=C(Cn1c(=O)oc2ccccc12)Nc3sc4CCCc4c3C#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A03 compound treatment 1185393.0 -430000.0 -0.81 1243236.0 -798000.0 -1.6 -1.6995 -0.9502 3631623 CBKinase1_021683 CCOc1ccccc1N2CC(CC2=O)C(=O)Nc3ccc(cc3)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A04 compound treatment 1323411.0 -292000.0 -0.55 1350059.0 -692000.0 -1.38 -1.3653 -0.9181 3631624 CBKinase1_021684 O=C(Cn1cnc2ccccc2c1=O)Nc3oc(c(c3C#N)c4ccccc4)c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A05 compound treatment 1842522.0 227000.0 0.43 1752055.0 -290000.0 -0.58 -0.1081 -0.1504 3631625 CBKinase1_021685 Oc1cc(=O)n(c(SCC(=O)Nc2ccccc2Cl)n1)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A06 compound treatment 689822.0 -926000.0 -1.74 1809659.0 -232000.0 -0.46 -1.5569 -0.8654 3631626 CBKinase1_021686 CCOC(=O)c1ccc(COC(=O)c2cc3ccccc3oc2=O)o1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A07 compound treatment 1213580.0 -402000.0 -0.75 1481197.0 -560000.0 -1.12 -1.3258 -0.9816 3631627 CBKinase1_021687 CC(C)(C)c1ccc(OCCn2c(CO)nc3ccccc23)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A08 compound treatment 1316104.0 -300000.0 -0.56 2026558.0 -15000.0 -0.03 -0.419 -0.7439 3631628 CBKinase1_021688 Oc1ccc(cc1O)C(=O)CSc2nnnn2c3cccc4ccccc34 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A09 compound treatment 1412292.0 -203000.0 -0.38 1539254.0 -502000.0 -1.0 -0.98 -0.9123 3631629 CBKinase1_021689 [O-][N+](=O)c1ccc(cc1)c2ccc(NC(=O)CSc3nnnn3c4ccccc4)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A10 compound treatment 747701.0 -868000.0 -1.63 1461586.0 -580000.0 -1.16 -1.972 -0.9861 3631630 CBKinase1_021690 Cc1c(NC(=O)CSc2nnc([nH]2)c3ccccc3)c(=O)n(c4ccccc4)n1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A11 compound treatment 1268564.0 -347000.0 -0.65 1898386.0 -143000.0 -0.29 -0.6632 -0.9318 3631631 CBKinase1_021691 COc1cc(NC(=O)CSc2nncn2C)cc(OC)c1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A12 compound treatment 1507858.0 -108000.0 -0.2 1509784.0 -532000.0 -1.06 -0.8947 -0.8269 3026881 CBKinase1_021692 Oc1cccnc1NC(=O)CCC2COc3ccccc3O2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A13 mock treatment 1074660.0 -541000.0 -1.02 1512677.0 -529000.0 -1.06 -1.4657 -0.9998 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A14 mock treatment 1370403.0 -245000.0 -0.46 1786673.0 -255000.0 -0.51 -0.6859 -0.9987 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A15 compound treatment 1697579.0 81900.0 0.15 1590659.0 -451000.0 -0.9 -0.5286 -0.5781 3631632 CBKinase1_021693 Brc1ccc2nc(cc(C(=O)NCCCn3ccnc3)c2c1)c4cccnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A16 compound treatment 1182011.0 -434000.0 -0.81 1706631.0 -335000.0 -0.67 -1.0491 -0.9953 3631633 CBKinase1_021694 CCOC(=O)c1cnn(c1N)c2nc(SC)nc3sc4CCCc4c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A17 compound treatment 1314457.0 -301000.0 -0.57 1733345.0 -308000.0 -0.62 -0.8355 -0.9991 3631634 CBKinase1_021695 CCNS(=O)(=O)c1ccc(NC(=O)c2cc(nc3c(C)c(Cl)ccc23)c4ccncc4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A18 compound treatment 1108814.0 -507000.0 -0.95 1557477.0 -484000.0 -0.97 -1.3571 -1.0 3631635 CBKinase1_021696 CSc1nc(SCC(=O)N(c2ccccc2)c3ccccc3)c4c5CCCc5sc4n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A19 compound treatment 1497412.0 -118000.0 -0.22 1641429.0 -400000.0 -0.8 -0.7226 -0.8705 3631636 CBKinase1_021697 Cn1cc(CNC(=O)c2cc(nc3ccc(Br)cc23)c4ccncc4)cn1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A20 compound treatment 1063741.0 -552000.0 -1.04 1222701.0 -819000.0 -1.64 -1.89 -0.9757 3631637 CBKinase1_021698 CCOc1ccc(NC(=O)CSc2nnc3c4c5CCCc5sc4nc(SC)n23)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A21 compound treatment 1401697.0 -214000.0 -0.4 1138575.0 -903000.0 -1.8 -1.5603 -0.8438 3631638 CBKinase1_021699 Cc1sc(NC(=O)c2cc(nc3ccc(C)cc23)c4cccnc4)c(C(=O)N)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A22 compound treatment 1243432.0 -372000.0 -0.7 1199956.0 -842000.0 -1.68 -1.6836 -0.9243 3631639 CBKinase1_021700 COc1ccccc1C2(CC(=O)O)CCOC(C2)C(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A23 compound treatment 1304921.0 -311000.0 -0.58 1166794.0 -875000.0 -1.75 -1.6489 -0.8946 3631640 CBKinase1_021701 Cc1sc(NC(=O)c2cc(nc3ccccc23)c4ccccc4)c(C(=O)NCc5cccnc5)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 A24 compound treatment 1007584.0 -608000.0 -1.14 1116055.0 -926000.0 -1.85 -2.1153 -0.9731 3631641 CBKinase1_021702 COC(=O)c1cc(OC)c(OC)cc1NC(=O)c2cc(nc3ccc(Br)cc23)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B01 compound treatment 1099546.0 -516000.0 -0.97 1162064.0 -880000.0 -1.76 -1.9282 -0.9606 3631642 CBKinase1_021703 Cc1cccc2c(cc(nc12)c3ccccc3Cl)C(=O)NCCc4ccc(cc4)S(=O)(=O)N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B02 compound treatment 1596823.0 -18900.0 -0.04 1815304.0 -226000.0 -0.45 -0.3449 -0.7601 3631643 CBKinase1_021704 COC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3cc(OC)ccc3OC)cc12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B03 compound treatment 1390590.0 -225000.0 -0.42 1675742.0 -366000.0 -0.73 -0.8159 -0.966 3631644 CBKinase1_021705 COc1ccccc1CCNC(=O)c2cc(nc3ccccc23)c4cccs4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B04 compound treatment 1127314.0 -488000.0 -0.92 2030894.0 -10700.0 -0.02 -0.6634 -0.7234 3631645 CBKinase1_021706 Cc1ccccc1c2nc(c(NCCN3CCOCC3)o2)S(=O)(=O)c4ccc(Cl)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B05 compound treatment 1336406.0 -279000.0 -0.52 1661752.0 -380000.0 -0.76 -0.9076 -0.9837 3631646 CBKinase1_021707 NS(=O)(=O)c1ccc(CNC(=O)c2cc(nc3ccc(Cl)cc23)c4ccccn4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B06 compound treatment 1775520.0 160000.0 0.3 1722173.0 -319000.0 -0.64 -0.2393 -0.3392 3631647 CBKinase1_021708 O=S(=O)(c1nc(oc1NCc2cccnc2)c3ccco3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B07 compound treatment 1519615.0 -96100.0 -0.18 1714189.0 -327000.0 -0.65 -0.5903 -0.8696 3631648 CBKinase1_021709 O=C(CCN1C(=O)c2ccccc2C1=O)Nc3ccc(cc3)c4nc5ccccc5o4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B08 compound treatment 1606864.0 -8820.0 -0.02 2001567.0 -40000.0 -0.08 -0.0683 -0.8357 3631649 CBKinase1_021710 Fc1ccc(cc1)S(=O)(=O)c2nc(oc2NCc3ccco3)c4ccccc4Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B09 compound treatment 632140.0 -984000.0 -1.85 926574.0 -1120000.0 -2.23 -2.8815 -0.9956 3631650 CBKinase1_021711 Oc1c(cc(Cl)c2cccnc12)C(Nc3ccccn3)c4c(F)cccc4Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B10 compound treatment 1812561.0 197000.0 0.37 2016815.0 -24800.0 -0.05 0.2263 0.6069 3631651 CBKinase1_021712 COC(=O)c1cccc(OCC(O)Cn2ccnc2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B11 compound treatment 1682406.0 66700.0 0.13 1948006.0 -93600.0 -0.19 -0.0437 -0.1941 3631652 CBKinase1_021713 Cc1ccc(cc1NC(=O)COc2ccc(I)cc2)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B12 compound treatment 1740041.0 124000.0 0.23 1574597.0 -467000.0 -0.93 -0.4949 -0.5144 3631653 CBKinase1_021714 OCCN(Cc1ccccc1)c2ncnc3c2sc4nc(N5CCOCC5)c6CCCCc6c43 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B13 mock treatment 1588411.0 -27300.0 -0.05 1551294.0 -490000.0 -0.98 -0.7292 -0.743 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B14 mock treatment 1336104.0 -280000.0 -0.52 1945706.0 -95900.0 -0.19 -0.5067 -0.9068 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B15 compound treatment 1482530.0 -133000.0 -0.25 1588481.0 -453000.0 -0.91 -0.8171 -0.8698 3631654 CBKinase1_021715 COC(=O)CNC(=O)c1cc(nc2ccc(Cl)cc12)c3ccccn3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B16 compound treatment 1377967.0 -238000.0 -0.45 1962480.0 -79100.0 -0.16 -0.4274 -0.9027 3631655 CBKinase1_021716 COc1ccc(cc1)N2C(=O)CC(SCC(=O)Nc3ccc(C)c(C)c3)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B17 compound treatment 899028.0 -717000.0 -1.35 2094128.0 52500.0 0.1 -0.8771 -0.65 3631656 CBKinase1_021717 CCOC(=O)c1c(C)c(sc1NC(=O)c2cc(nc3c(C)cc(C)cc23)c4cccnc4)C(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B18 compound treatment 1566753.0 -48900.0 -0.09 1732826.0 -309000.0 -0.62 -0.5013 -0.8035 3631657 CBKinase1_021718 Fc1cccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccc(I)cc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B19 compound treatment 1273119.0 -343000.0 -0.64 1473640.0 -568000.0 -1.14 -1.2574 -0.9638 3631658 CBKinase1_021719 Cc1cccc2c(cc(nc12)c3ccccc3Cl)C(=O)NCCN4CCOCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B20 compound treatment 1438586.0 -177000.0 -0.33 1377099.0 -665000.0 -1.33 -1.1742 -0.8577 3631659 CBKinase1_021720 Cc1cccc2c(C)cc(SCC(=O)Nc3ccccc3)nc12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B21 compound treatment 1054366.0 -561000.0 -1.05 1345051.0 -697000.0 -1.39 -1.7296 -0.9906 3631660 CBKinase1_021721 CC(C)Oc1cccc(c1)c2cc(C(=O)NCc3ccco3)c4ccccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B22 compound treatment 1311212.0 -304000.0 -0.57 1586994.0 -455000.0 -0.91 -1.0467 -0.975 3631661 CBKinase1_021722 COc1ccc(NC(=O)CSc2c(C)nn(c2C)c3nnc(C)c(=O)[nH]3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B23 compound treatment 693193.0 -922000.0 -1.73 1094011.0 -948000.0 -1.89 -2.5638 -0.999 3631662 CBKinase1_021723 CC(=O)Nc1cccc(NC(=O)c2cc(nc3ccc(Br)cc23)c4cccnc4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 B24 compound treatment 1187773.0 -428000.0 -0.8 1118156.0 -923000.0 -1.85 -1.8731 -0.9306 3631663 CBKinase1_021724 COc1cccc(c1)C(=O)c2oc3ccccc3c2NC(=O)COc4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C01 compound treatment 1498370.0 -117000.0 -0.22 1956096.0 -85500.0 -0.17 -0.2766 -0.9921 3631664 CBKinase1_021725 O=C(CSc1nc(Nc2ccccc2)nc(n1)N3CCOCC3)N4CCc5ccccc45 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C02 compound treatment 1377244.0 -238000.0 -0.45 2096870.0 55300.0 0.11 -0.2384 -0.5171 3631665 CBKinase1_021726 Brc1ccc2n(CC(=O)Nc3sc4CCCCc4c3C#N)c(=O)oc2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C03 compound treatment 1291475.0 -324000.0 -0.61 2225276.0 184000.0 0.37 -0.1708 -0.2403 3631666 CBKinase1_021727 COCc1nc2ccccc2n1CCOc3ccc(Cl)cc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C04 compound treatment 1444379.0 -171000.0 -0.32 2264813.0 223000.0 0.45 0.0881 0.1601 3631667 CBKinase1_021728 CC(=O)c1c(C)oc(NC(=O)Cn2cnc3ccccc3c2=O)c1C#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C05 compound treatment 1727872.0 112000.0 0.21 2077420.0 35800.0 0.07 0.1995 0.897 3631668 CBKinase1_021729 Oc1cc(=O)n(c(SCC(=O)Nc2ccc3ccccc3c2)n1)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C06 compound treatment 1787407.0 172000.0 0.32 2023962.0 -17600.0 -0.04 0.203 0.626 3631669 CBKinase1_021730 CCOC(=O)c1ccc(COC(=O)c2cc(O)nc3ccccc23)o1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C07 compound treatment 1083240.0 -532000.0 -1.0 2281779.0 240000.0 0.48 -0.3674 -0.3313 3631670 CBKinase1_021731 CC(O)c1nc2ccccc2n1CCOc3ccc(F)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C08 compound treatment 1802780.0 187000.0 0.35 2248126.0 207000.0 0.41 0.5402 0.9968 3631671 CBKinase1_021732 CN(C)c1nc(N)nc(CSc2nnnn2c3ccc(F)cc3)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C09 compound treatment 1334860.0 -281000.0 -0.53 2273269.0 232000.0 0.46 -0.0454 -0.0647 3631672 CBKinase1_021733 Oc1ccc(Cl)cc1NC(=O)CSc2nnnn2c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C10 compound treatment 1771192.0 156000.0 0.29 2118956.0 77400.0 0.15 0.3158 0.9558 3631673 CBKinase1_021734 FC(F)(F)c1cccc(NC(=O)CSc2nnc([nH]2)c3ccccc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C11 mock treatment 1610231.0 -5450.0 -0.01 1826716.0 -215000.0 -0.43 -0.3109 -0.7237 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C12 mock treatment 1647359.0 31700.0 0.06 2021219.0 -20400.0 -0.04 0.0132 0.1836 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C13 compound treatment 1609060.0 -6620.0 -0.01 1816328.0 -225000.0 -0.45 -0.3272 -0.7264 3631674 CBKinase1_021735 O=C(NC1CCCC1)c2c(NC(=O)c3cc(nc4ccccc34)c5ccccn5)sc6CCCc26 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C14 compound treatment 1452391.0 -163000.0 -0.31 2117657.0 76100.0 0.15 -0.1093 -0.3194 1259601 CBKinase1_021736 Cn1c(=O)n(C)c2nc(N3CCOCC3)n(CCCN)c2c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C15 mock treatment 1358470.0 -257000.0 -0.48 2173136.0 132000.0 0.26 -0.1556 -0.2829 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C16 mock treatment 1520640.0 -95000.0 -0.18 1751171.0 -290000.0 -0.58 -0.5366 -0.8837 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C17 compound treatment 1743488.0 128000.0 0.24 1770829.0 -271000.0 -0.54 -0.213 -0.3598 3631675 CBKinase1_021737 Cc1ccc(c(C)c1)c2cc(C(=O)NCCN3CCOCC3)c4cccc(C)c4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C18 compound treatment 1098769.0 -517000.0 -0.97 1824809.0 -217000.0 -0.43 -0.9926 -0.934 3631676 CBKinase1_021738 CCOc1ccc(NC(=O)Cn2c(=O)n(c3ccc(Cl)cc3)c(=O)c4c5CCCc5sc24)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C19 compound treatment 1665403.0 49700.0 0.09 2012866.0 -28700.0 -0.06 0.0254 0.2316 3631677 CBKinase1_021739 Brc1ccc2nc(cc(C(=O)NCCCN3CCCC3=O)c2c1)c4ccncc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C20 compound treatment 2008357.0 393000.0 0.74 1747968.0 -294000.0 -0.59 0.1063 0.1128 3631678 CBKinase1_021740 CC1(C)Cc2nc3nc(SCC(=O)Nc4ccccc4)n(c5ccccc5)c(=O)c3cc2CO1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C21 compound treatment 1141462.0 -474000.0 -0.89 1671781.0 -370000.0 -0.74 -1.1522 -0.9957 3631679 CBKinase1_021741 COc1ccccc1CCNC(=O)c2cc(nc3c(C)c(Cl)ccc23)c4ccncc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C22 compound treatment 1198682.0 -417000.0 -0.78 1335139.0 -706000.0 -1.41 -1.552 -0.9613 3631680 CBKinase1_021742 COc1ccccc1CNC(=O)c2cc(nc3c(Cl)cccc23)c4ccncc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C23 compound treatment 1304178.0 -312000.0 -0.58 1746935.0 -295000.0 -0.59 -0.83 -1.0 3631681 CBKinase1_021743 COc1ccc(CCNC(=O)c2cc(nc3c(Cl)cccc23)c4ccccn4)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 C24 compound treatment 1060151.0 -556000.0 -1.04 1388402.0 -653000.0 -1.31 -1.6606 -0.9938 3631682 CBKinase1_021744 Brc1ccc2nc(cc(C(=O)NCc3cc4ccccc4[nH]3)c2c1)c5ccccn5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D01 compound treatment 1381075.0 -235000.0 -0.44 1886539.0 -155000.0 -0.31 -0.5306 -0.9852 3631683 CBKinase1_021745 Cc1sc(NC(=O)c2cc(nc3ccccc23)c4ccccn4)c(C(=O)NC5CCCCC5)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D02 compound treatment 1587634.0 -28000.0 -0.05 2158762.0 117000.0 0.23 0.1283 0.5347 3631684 CBKinase1_021746 COc1ccc(cc1)N(C(=O)c2ccncc2)S(=O)(=O)c3ccc4N(C)C(=O)c5cccc3c45 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D03 compound treatment 645531.0 -970000.0 -1.82 668056.0 -1370000.0 -2.75 -3.2291 -0.9801 3631685 CBKinase1_021747 CC(CN1CCCCC1)NC(=O)c2cc(nc3ccc(Br)cc23)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D04 compound treatment 1668126.0 52400.0 0.1 1964964.0 -76600.0 -0.15 -0.0387 -0.2125 3631686 CBKinase1_021748 Fc1ccc(cc1)c2nc(c(NCc3cccnc3)o2)S(=O)(=O)c4ccc(Cl)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D05 compound treatment 1652189.0 36500.0 0.07 2078960.0 37400.0 0.07 0.1013 0.9991 3631687 CBKinase1_021749 Cc1ccc2nc(cc(C(=O)NCc3cnn(C)c3)c2c1)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D06 compound treatment 1431333.0 -184000.0 -0.35 1868020.0 -174000.0 -0.35 -0.49 -1.0 3631688 CBKinase1_021750 O=S(=O)(c1nc(oc1NCc2ccco2)c3cccs3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D07 compound treatment 1393794.0 -222000.0 -0.42 2180666.0 139000.0 0.28 -0.098 -0.1957 3631689 CBKinase1_021751 Cc1ccc(cc1)c2nnc(SCC(=O)c3ccccc3)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D08 compound treatment 1667066.0 51400.0 0.1 2142712.0 101000.0 0.2 0.2111 0.9427 3631690 CBKinase1_021752 Fc1ccccc1c2nc(c(NCc3cccnc3)o2)S(=O)(=O)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D09 compound treatment 1562814.0 -52900.0 -0.1 2235032.0 193000.0 0.39 0.2032 0.5091 3631691 CBKinase1_021753 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N)c2ccc(Cl)c(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D10 compound treatment 1268643.0 -347000.0 -0.65 1706540.0 -335000.0 -0.67 -0.9342 -0.9999 3631692 CBKinase1_021754 OCCNC(=O)c1cccc(Nc2nc(c3ccccc3)c4cc(Cl)ccc4n2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D11 mock treatment 1610566.0 -5120.0 -0.01 2048560.0 6950.0 0.01 0.003 0.1798 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D12 mock treatment 1657711.0 42000.0 0.08 2327968.0 286000.0 0.57 0.4605 0.797 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D13 compound treatment 1204878.0 -411000.0 -0.77 1884564.0 -157000.0 -0.31 -0.7673 -0.9215 3631693 CBKinase1_021755 Cc1ccccc1c2cc(C(=O)NCCCn3cc(Br)cn3)c4ccccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D14 compound treatment 1644151.0 28500.0 0.05 2320139.0 279000.0 0.56 0.4314 0.7714 3631694 CBKinase1_021756 COc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccccc3)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D15 mock treatment 1519261.0 -96400.0 -0.18 1919600.0 -122000.0 -0.24 -0.3004 -0.9892 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D16 mock treatment 1560013.0 -55700.0 -0.1 1931456.0 -110000.0 -0.22 -0.2296 -0.942 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D17 compound treatment 1486126.0 -130000.0 -0.24 1558063.0 -484000.0 -0.97 -0.8554 -0.8583 3631695 CBKinase1_021757 Brc1ccc2nc(cc(C(=O)NCc3ccccn3)c2c1)c4cccnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D18 compound treatment 1318841.0 -297000.0 -0.56 2082371.0 40800.0 0.08 -0.3364 -0.5974 3631696 CBKinase1_021758 COc1ccccc1NC(=O)CSC2CC(=O)N(C2=O)c3ccc(I)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D19 compound treatment 1321452.0 -294000.0 -0.55 2097675.0 56100.0 0.11 -0.3113 -0.5524 3631697 CBKinase1_021759 CCc1ccc(s1)c2cc(C(=O)NCc3ccco3)c4ccccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D20 compound treatment 1101076.0 -515000.0 -0.97 1664412.0 -377000.0 -0.75 -1.2162 -0.9925 3631698 CBKinase1_021760 COc1ccc(NC(=O)CSc2cc(C)c3cccc(C)c3n2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D21 compound treatment 1204589.0 -411000.0 -0.77 2136646.0 95000.0 0.19 -0.4114 -0.5176 3631699 CBKinase1_021761 Cc1ccc(cc1)c2cc(C(=O)NCc3cccnc3)c4cc(Br)ccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D22 compound treatment 1612864.0 -2820.0 -0.01 1567606.0 -474000.0 -0.95 -0.6736 -0.711 3631700 CBKinase1_021762 COc1ccc(NC(=O)C2CCCCC2C(=O)O)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D23 compound treatment 1270823.0 -345000.0 -0.65 1409524.0 -632000.0 -1.26 -1.3511 -0.9518 3631701 CBKinase1_021763 Cc1cc(CNC(=O)c2cc(nc3ccc(Cl)cc23)c4cccnc4)nn1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 D24 compound treatment 1479035.0 -137000.0 -0.26 1730190.0 -311000.0 -0.62 -0.6215 -0.9232 3631702 CBKinase1_021764 COc1cccc(c1)C(=O)c2oc3ccccc3c2NC(=O)CCc4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E01 mock treatment 1362877.0 -253000.0 -0.47 1996184.0 -45400.0 -0.09 -0.3998 -0.8274 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E02 mock treatment 1694059.0 78400.0 0.15 2252403.0 211000.0 0.42 0.402 0.9007 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E03 compound treatment 1820604.0 205000.0 0.38 2288576.0 247000.0 0.49 0.6211 0.9924 3631703 CBKinase1_021765 COCc1nc2ccccc2n1CCOc3ccc(Br)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E04 compound treatment 1763172.0 147000.0 0.28 2318836.0 277000.0 0.55 0.5876 0.9486 3631704 CBKinase1_021766 O=C(Cn1cnc2ccccc2c1=O)Nc3sc4CCCc4c3C#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E05 compound treatment 1571244.0 -44400.0 -0.08 2085017.0 43400.0 0.09 0.0024 0.0196 3631705 CBKinase1_021767 COc1ccc(C)cc1NC(=O)CS(=O)(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E06 compound treatment 1515184.0 -100000.0 -0.19 2037036.0 -4570.0 -0.01 -0.1399 -0.7405 3631706 CBKinase1_021768 CCOC(=O)c1ccc(COc2ccc(cc2)c3cnc4ccccc4n3)o1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E07 compound treatment 1599655.0 -16000.0 -0.03 2289143.0 248000.0 0.49 0.3286 0.6629 3631707 CBKinase1_021769 CC(O)c1nc2ccccc2n1CCOc3ccc(Br)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E08 compound treatment 1907648.0 292000.0 0.55 1976496.0 -65100.0 -0.13 0.2956 0.5246 3631708 CBKinase1_021770 Cc1c(NC(=O)CSc2nnnn2c3ccc(F)cc3)c(=O)n(c4ccccc4)n1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E09 mock treatment 1826736.0 211000.0 0.4 2155429.0 114000.0 0.23 0.441 0.9653 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E10 mock treatment 1684276.0 68600.0 0.13 1928174.0 -113000.0 -0.23 -0.0693 -0.2656 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E11 compound treatment 1866467.0 251000.0 0.47 1339892.0 -702000.0 -1.4 -0.6588 -0.4453 3631709 CBKinase1_021771 COc1ccc(cc1NC(=O)CSc2nncn2C)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E12 compound treatment 1766573.0 151000.0 0.28 1953564.0 -88000.0 -0.18 0.0759 0.2275 3631710 CBKinase1_021772 O=C(CCC1COc2ccccc2O1)NCc3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E13 compound treatment 1935968.0 320000.0 0.6 1640517.0 -401000.0 -0.8 -0.1417 -0.1414 3631711 CBKinase1_021773 COc1ccccc1CCNC(=O)c2cc(nc3ccccc23)c4ccc(C)o4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E14 compound treatment 1693709.0 78000.0 0.15 1422109.0 -619000.0 -1.24 -0.7719 -0.6191 1569922 CBKinase1_021774 CCC(CO)(C(=O)OC1CC2CCC(C1)N2C)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E15 compound treatment 1514183.0 -101000.0 -0.19 1573682.0 -468000.0 -0.94 -0.796 -0.834 3631712 CBKinase1_021775 Cc1c(Cl)ccc2c(cc(nc12)c3ccncc3)C(=O)NCCCn4cc(Br)cn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E16 compound treatment 1223060.0 -393000.0 -0.74 1979558.0 -62000.0 -0.12 -0.6089 -0.8146 3631713 CBKinase1_021776 CCC1(C)Cc2c(CO1)sc3nc(SC)nc(SCC(=O)OC)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E17 mock treatment 1758776.0 143000.0 0.27 2460478.0 419000.0 0.84 0.7819 0.8893 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E18 mock treatment 2072114.0 456000.0 0.86 1799965.0 -242000.0 -0.48 0.2644 0.2688 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E19 compound treatment 1137167.0 -479000.0 -0.9 1200188.0 -841000.0 -1.68 -1.8244 -0.9569 3631714 CBKinase1_021777 COc1ccc(CN2CCN(CC2)C(=O)c3cc(nc4ccc(Cl)cc34)c5cccnc5)c(OC)c1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E20 compound treatment 1372888.0 -243000.0 -0.46 1444508.0 -597000.0 -1.19 -1.1662 -0.9129 3631715 CBKinase1_021778 Clc1ccc(NC(=O)CSc2nc3nc4CCCCc4cc3c(=O)n2c5ccccc5)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E21 compound treatment 1279705.0 -336000.0 -0.63 1546866.0 -495000.0 -0.99 -1.1452 -0.9764 3631716 CBKinase1_021779 Cc1cc(CNC(=O)c2cc(nc3ccccc23)c4ccccc4)nn1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E22 compound treatment 1568959.0 -46700.0 -0.09 1473216.0 -568000.0 -1.14 -0.8653 -0.7594 3631717 CBKinase1_021780 Cc1c(Cl)ccc2c(cc(nc12)c3cccnc3)C(=O)Nc4ccc(cc4)S(=O)(=O)N5CCOCC5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E23 compound treatment 1262834.0 -353000.0 -0.66 1793303.0 -248000.0 -0.5 -0.8193 -0.9899 3631718 CBKinase1_021781 Clc1ccc2nc(cc(C(=O)NCc3ccco3)c2c1)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 E24 compound treatment 1128568.0 -487000.0 -0.91 1092093.0 -950000.0 -1.9 -1.9886 -0.944 3631719 CBKinase1_021782 Brc1ccc2nc(cc(C(=O)NCCCN3CCCC3=O)c2c1)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F01 mock treatment 1351086.0 -265000.0 -0.5 1438031.0 -604000.0 -1.21 -1.2043 -0.9231 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F02 mock treatment 1533376.0 -82300.0 -0.15 1679480.0 -362000.0 -0.72 -0.621 -0.8392 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F03 compound treatment 1800537.0 185000.0 0.35 2139990.0 98400.0 0.2 0.3844 0.9638 3631720 CBKinase1_021783 Cc1nn(Cc2ccccc2C)c(C)c1NC(=O)c3cc(nc4c(C)cc(C)cc34)c5cccnc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F04 compound treatment 1704549.0 88900.0 0.17 1861196.0 -180000.0 -0.36 -0.137 -0.3448 3631721 CBKinase1_021784 Fc1ccc(cc1)c2nc(c(NCc3cccnc3)o2)S(=O)(=O)c4ccc(Br)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F05 compound treatment 1715055.0 99400.0 0.19 2013169.0 -28400.0 -0.06 0.0917 0.4703 3631722 CBKinase1_021785 COC(=O)c1c(NC(=O)c2cc(nc3ccccc23)c4ccc(C)o4)scc1c5cccnc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F06 compound treatment 1802229.0 187000.0 0.35 2235094.0 193000.0 0.39 0.5211 0.9988 3631723 CBKinase1_021786 O=S(=O)(c1nc(oc1NCC2CCCO2)c3cccs3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F07 compound treatment 1768775.0 153000.0 0.29 2156361.0 115000.0 0.23 0.3654 0.9938 3631724 CBKinase1_021787 O=C(Nc1ccccc1C(=O)OCc2cccc(c2)C(=O)c3ccccc3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F08 compound treatment 2047952.0 432000.0 0.81 2064403.0 22800.0 0.05 0.6061 0.7456 3631725 CBKinase1_021788 Cc1ccc(cc1)S(=O)(=O)c2nc(oc2NCC3CCCO3)c4ccccc4F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F09 mock treatment 2322282.0 707000.0 1.33 2492973.0 451000.0 0.9 1.5759 0.9823 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F10 mock treatment 1918775.0 303000.0 0.57 2036604.0 -5000.0 -0.01 0.3953 0.6946 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F11 compound treatment 2212741.0 597000.0 1.12 2406170.0 365000.0 0.73 1.3078 0.9782 3631726 CBKinase1_021789 COc1ccc(cc1)C(=O)CSc2nnc([nH]2)c3ccc(C)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F12 compound treatment 1942244.0 327000.0 0.61 2037957.0 -3650.0 -0.01 0.4283 0.6986 3631727 CBKinase1_021790 CC1(C)Cc2c(C#N)c(OCC(=O)c3ccc(Cl)cc3)nc(c4ccco4)c2CO1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F13 compound treatment 1963283.0 348000.0 0.65 2124755.0 83100.0 0.17 0.5789 0.8597 3631728 CBKinase1_021791 Cc1ccc2nc(cc(C(=O)Nc3scc(c3C(=O)N)c4ccc(C)c(C)c4)c2c1)c5cccnc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F14 compound treatment 2057710.0 442000.0 0.83 2248560.0 207000.0 0.41 0.8793 0.9483 3631729 CBKinase1_021792 Cc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccc(F)cc3)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F15 compound treatment 1018655.0 -597000.0 -1.12 969741.0 -1070000.0 -2.14 -2.3074 -0.9543 3631730 CBKinase1_021793 CN(C)CCNC(=O)c1cc(nc2c(Cl)cccc12)c3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F16 compound treatment 1869142.0 253000.0 0.48 2040783.0 -823.0 0.0 0.3353 0.7047 3631731 CBKinase1_021794 COc1ccc(cc1)N2C(=O)CC(SCC(=O)Nc3c(C)cccc3C)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F17 mock treatment 1844742.0 229000.0 0.43 2026954.0 -14700.0 -0.03 0.2834 0.6574 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F18 mock treatment 1899542.0 284000.0 0.53 2349288.0 308000.0 0.61 0.8117 0.9975 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F19 compound treatment 1447532.0 -168000.0 -0.32 1986985.0 -54600.0 -0.11 -0.3004 -0.8994 3631732 CBKinase1_021795 COC(=O)c1c(NC(=O)c2cc(nc3ccccc23)c4cccnc4)scc1c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F20 compound treatment 1449282.0 -166000.0 -0.31 1485968.0 -556000.0 -1.11 -1.0062 -0.8722 3631733 CBKinase1_021796 CCOc1ccccc1NC(=O)CSc2cc(C)c3cccc(C)c3n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F21 compound treatment 1066468.0 -549000.0 -1.03 1293268.0 -748000.0 -1.5 -1.7867 -0.9835 3631734 CBKinase1_021797 CC(=O)Nc1cccc(NC(=O)c2cc(nc3ccc(Cl)cc23)c4cccnc4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F22 compound treatment 1522967.0 -92700.0 -0.17 2067564.0 26000.0 0.05 -0.0864 -0.4757 3631735 CBKinase1_021798 Brc1ccc2oc(=O)c(cc2c1)C(=O)NCCN3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F23 compound treatment 1375215.0 -240000.0 -0.45 1802213.0 -239000.0 -0.48 -0.6575 -0.9996 3631736 CBKinase1_021799 Cc1cc(nn1CCCNC(=O)c2cc(nc3ccc(Cl)cc23)c4cccnc4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 F24 compound treatment 1243144.0 -373000.0 -0.7 1046840.0 -995000.0 -1.99 -1.9004 -0.9017 3631737 CBKinase1_021800 COc1cccc(C2N(C(=O)C(=C2C(=O)c3cc4ccccc4o3)O)c5nc(C)c(C)s5)c1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G01 compound treatment 1351818.0 -264000.0 -0.5 1827018.0 -215000.0 -0.43 -0.6535 -0.9974 3631738 CBKinase1_021801 CC(=O)c1ccc(NC(=O)COc2ccccc2C(=O)Nc3ccccc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G02 compound treatment 1609368.0 -6310.0 -0.01 2151208.0 110000.0 0.22 0.1465 0.6679 3631739 CBKinase1_021802 O=C(CCn1cnc2ccccc2c1=O)Nc3ccc4CCc5cccc3c54 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G03 mock treatment 1872482.0 257000.0 0.48 2606731.0 565000.0 1.13 1.1396 0.9279 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G04 mock treatment 1979280.0 364000.0 0.68 2229935.0 188000.0 0.38 0.7488 0.9607 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G05 compound treatment 2183025.0 567000.0 1.07 2684339.0 643000.0 1.28 1.6615 0.9957 3631740 CBKinase1_021803 COc1cc(OC)c(NC(=O)CS(=O)(=O)c2ccccc2)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G06 compound treatment 1833923.0 218000.0 0.41 2404224.0 363000.0 0.72 0.8022 0.9635 3631741 CBKinase1_021804 CCOC(=O)c1ccc(COC(=O)c2cc3ccccc3cc2O)o1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G07 compound treatment 1915503.0 300000.0 0.56 2538186.0 497000.0 0.99 1.0998 0.9639 3631742 CBKinase1_021805 FC(F)(F)c1cccc(NC(=O)CSc2nnc(o2)c3ccncc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G08 compound treatment 1971813.0 356000.0 0.67 2752781.0 711000.0 1.42 1.4778 0.9408 3631743 CBKinase1_021806 Cc1ccc(NC(=O)CSc2nnc([nH]2)c3ccccc3Cl)cc1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G09 compound treatment 2114842.0 499000.0 0.94 2604231.0 563000.0 1.12 1.4578 0.9959 1162956 CBKinase1_021807 CCn1c2ccccc2c3cc(NC(=O)CSc4nnnn4c5ccccc5)ccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G10 compound treatment 2106393.0 491000.0 0.92 2683683.0 642000.0 1.28 1.5588 0.9868 3631744 CBKinase1_021808 CCOc1ccccc1NC(=O)C2C(C3CC2C=C3)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G11 compound treatment 2229722.0 614000.0 1.15 2622522.0 581000.0 1.16 1.6361 1.0 3631745 CBKinase1_021809 Fc1cccc(NC(=O)CSc2ccccn2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G12 compound treatment 1989480.0 374000.0 0.7 2068501.0 26900.0 0.05 0.5342 0.759 3631746 CBKinase1_021810 Fc1ccccc1C(=O)Nc2ccc(NC(=O)CCC3COc4ccccc4O3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G13 compound treatment 1997227.0 382000.0 0.72 2513736.0 472000.0 0.94 1.1737 0.9908 3631747 CBKinase1_021811 Cc1cc(C)c2nc(cc(C(=O)Nc3cccc(Cn4cccn4)c3)c2c1)c5ccccn5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G14 compound treatment 1743198.0 128000.0 0.24 2279253.0 238000.0 0.47 0.5051 0.9497 3631748 CBKinase1_021812 CC(=O)c1ccc(NC(=O)CSc2nnc3n(c4ccccc4)c(=O)c5c6CC(C)(C)OCc6sc5n23)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G15 compound treatment 1795869.0 180000.0 0.34 1944614.0 -97000.0 -0.19 0.1021 0.2619 3631749 CBKinase1_021813 CCc1c(C)sc(NC(=O)c2cc(nc3c(C)cccc23)c4ccccn4)c1C(=O)N5CCCCC5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G16 compound treatment 1923322.0 308000.0 0.58 2493144.0 452000.0 0.9 1.0465 0.9767 3631750 CBKinase1_021814 CCC1(C)Cc2c(CO1)sc3nc(SC)nc(SCC(=O)Nc4ccc(C)cc4)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G17 compound treatment 1109063.0 -507000.0 -0.95 1267803.0 -774000.0 -1.55 -1.7661 -0.9727 3631751 CBKinase1_021815 Cc1nn(Cc2ccc(F)cc2)c(C)c1NC(=O)c3cc(nc4c(Cl)cccc34)c5cccnc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G18 compound treatment 1859231.0 244000.0 0.46 2365417.0 324000.0 0.65 0.7809 0.9855 3631752 CBKinase1_021816 CCn1c(=O)c2c3CCCCc3sc2n4c(SCC(=O)Nc5ccc(Cl)cc5)nnc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G19 mock treatment 1761912.0 146000.0 0.27 2371083.0 329000.0 0.66 0.6598 0.9247 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G20 mock treatment 1616458.0 776.0 0.0 1970395.0 -71200.0 -0.14 -0.0996 -0.6998 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G21 compound treatment 1627513.0 11800.0 0.02 2070098.0 28500.0 0.06 0.056 0.9157 3631753 CBKinase1_021817 COC(=O)c1sccc1NC(=O)c2cc(nc3ccc(Cl)cc23)c4cccnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G22 compound treatment 1637797.0 22100.0 0.04 2306093.0 264000.0 0.53 0.4032 0.7603 3631754 CBKinase1_021818 O=C(NCCCN1CCCC1=O)c2cc(nc3ccccc23)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G23 compound treatment 1633321.0 17600.0 0.03 1901205.0 -140000.0 -0.28 -0.175 -0.6194 3631755 CBKinase1_021819 NS(=O)(=O)c1ccc(CNC(=O)c2cc(nc3ccc(Br)cc23)c4cccnc4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 G24 compound treatment 1488776.0 -127000.0 -0.24 1592046.0 -450000.0 -0.9 -0.8038 -0.8647 3631756 CBKinase1_021820 COc1cc2c(cc1NC(=O)c3cc(nc4ccc(C)cc34)c5cccnc5)oc6ccccc62 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H01 compound treatment 1445793.0 -170000.0 -0.32 1816632.0 -225000.0 -0.45 -0.5435 -0.9858 3631757 CBKinase1_021821 CCCc1ccc(cc1)c2cc(C(=O)NCc3ccccn3)c4ccccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H02 compound treatment 1721356.0 106000.0 0.2 1960203.0 -81400.0 -0.16 0.0252 0.0984 3631758 CBKinase1_021822 Cc1ccc(cc1)c2nc(c(NCc3ccco3)o2)S(=O)(=O)c4ccc(F)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H03 mock treatment 1878499.0 263000.0 0.49 2173273.0 132000.0 0.26 0.535 0.9567 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H04 mock treatment 1834936.0 219000.0 0.41 2220640.0 179000.0 0.36 0.5441 0.9976 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H05 compound treatment 963659.0 -652000.0 -1.22 1333583.0 -708000.0 -1.42 -1.8662 -0.9974 3631759 CBKinase1_021823 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cc(nc3c(C)c(C)ccc23)c4ccccn4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H06 compound treatment 1741694.0 126000.0 0.24 2270419.0 229000.0 0.46 0.4907 0.9529 3631760 CBKinase1_021824 Cc1ccc(cc1)S(=O)(=O)c2nc(oc2NCc3cccnc3)c4cccs4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H07 compound treatment 2014692.0 399000.0 0.75 2321965.0 280000.0 0.56 0.9259 0.9898 3631761 CBKinase1_021825 CCn1c(SCC(=O)Nc2cccc(F)c2)nnc1c3cc4cc(Br)ccc4o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H08 compound treatment 1743144.0 127000.0 0.24 2202256.0 161000.0 0.32 0.3962 0.9895 3631762 CBKinase1_021826 Fc1ccccc1c2nc(c(NCCN3CCOCC3)o2)S(=O)(=O)c4ccc(Cl)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H09 compound treatment 1874818.0 259000.0 0.49 2051684.0 10100.0 0.02 0.3582 0.7358 3631763 CBKinase1_021827 Brc1cccc(NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H10 compound treatment 1302439.0 -313000.0 -0.59 1609514.0 -432000.0 -0.86 -1.0265 -0.9825 1251565 CBKinase1_021828 Clc1ccc(cc1)C2=NN(C(C2)c3ccco3)C(=O)CCN4CCCCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H11 compound treatment 2373680.0 758000.0 1.42 2735414.0 694000.0 1.39 1.9868 0.9999 3631764 CBKinase1_021829 O=C(NCc1ccco1)c2cccc(c2)S(=O)(=O)N3CCCCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H12 compound treatment 2289852.0 674000.0 1.27 2661298.0 620000.0 1.24 1.7707 0.9999 3631765 CBKinase1_021830 Clc1ccc(OCC(=O)Nc2ccccc2C(=O)NC3CCCCC3)c(Br)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H13 compound treatment 2110544.0 495000.0 0.93 2591764.0 550000.0 1.1 1.4344 0.9965 3631766 CBKinase1_021831 COC(=O)c1c(C)c(sc1NC(=O)c2cc(nc3ccc(Br)cc23)c4ccccn4)C(=O)N(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H14 compound treatment 2245950.0 630000.0 1.18 2857517.0 816000.0 1.63 1.9898 0.9876 3631767 CBKinase1_021832 Cc1cc(C)cc(NC(=O)CSC2CC(=O)N(C2=O)c3ccc(F)cc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H15 compound treatment 2019962.0 404000.0 0.76 2316143.0 275000.0 0.55 0.9247 0.9873 3631768 CBKinase1_021833 CC1CCc2c(C(=O)N)c(NC(=O)c3cc(nc4ccc(Cl)cc34)c5cccnc5)sc2C1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H16 compound treatment 2317625.0 702000.0 1.32 2597011.0 555000.0 1.11 1.7168 0.9964 3631769 CBKinase1_021834 COc1ccc(cc1)N2C(=O)CC(SCC(=O)Nc3ccccc3F)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H17 compound treatment 2375154.0 759000.0 1.43 2588270.0 547000.0 1.09 1.7808 0.9914 3631770 CBKinase1_021835 CCOC(=O)CNC(=O)c1cc(nc2c(C)c(Cl)ccc12)c3ccccn3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H18 compound treatment 2230684.0 615000.0 1.15 2569155.0 528000.0 1.05 1.562 0.999 3631771 CBKinase1_021836 COc1cccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccc(I)cc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H19 mock treatment 1640767.0 25100.0 0.05 2106351.0 64700.0 0.13 0.1248 0.9063 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H20 mock treatment 1977603.0 362000.0 0.68 2495288.0 454000.0 0.91 1.1216 0.9899 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H21 compound treatment 1461298.0 -154000.0 -0.29 2276192.0 235000.0 0.47 0.1266 0.2297 3631772 CBKinase1_021837 CN(C)C(=O)c1sc(NC(=O)c2cc(nc3ccc(Cl)cc23)c4ccccn4)c(C#N)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H22 compound treatment 1764598.0 149000.0 0.28 2320084.0 278000.0 0.56 0.5913 0.9493 1986151 CBKinase1_021838 CC(NCC(O)Cn1c2ccccc2c3ccccc13)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H23 compound treatment 1710173.0 94500.0 0.18 2356471.0 315000.0 0.63 0.5704 0.8724 3631773 CBKinase1_021839 Cc1cc(CNC(=O)c2cc(nc3c(C)cc(C)cc23)c4ccccn4)nn1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 H24 compound treatment 1742088.0 126000.0 0.24 1936621.0 -105000.0 -0.21 0.0194 0.0613 3631774 CBKinase1_021840 COc1cccc2cc(oc12)C(=O)C3=C(O)C(=O)N(C3c4ccco4)c5nc(C)c(C)s5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I01 compound treatment 1580316.0 -35400.0 -0.07 1500647.0 -541000.0 -1.08 -0.8115 -0.7491 3631775 CBKinase1_021841 COc1ccccc1NC(=O)COc2ccccc2C(=O)Nc3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I02 compound treatment 1426140.0 -190000.0 -0.36 1871117.0 -170000.0 -0.34 -0.4926 -0.9998 3631776 CBKinase1_021842 FC(F)(F)c1cccc(NC(=O)CCn2cnc3ccccc3c2=O)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I03 compound treatment 1214343.0 -401000.0 -0.75 2203406.0 162000.0 0.32 -0.3041 -0.3709 3631777 CBKinase1_021843 OCc1nc2ccccc2n1CCCOc3ccc(Br)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I04 compound treatment 1728277.0 113000.0 0.21 2249124.0 208000.0 0.41 0.4428 0.9511 3631778 CBKinase1_021844 Nc1nnc(SCCN2C(=O)c3ccccc3S2(=O)=O)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I05 mock treatment 1912512.0 297000.0 0.56 2441845.0 400000.0 0.8 0.9597 0.9844 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I06 mock treatment 1967953.0 352000.0 0.66 2551011.0 509000.0 1.02 1.1876 0.9782 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I07 compound treatment 1890337.0 275000.0 0.52 2629054.0 587000.0 1.17 1.1948 0.9317 1228908 CBKinase1_021845 COc1cc(Cl)c(C)cc1NC(=O)CSc2nc3ccccc3s2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I08 compound treatment 1727640.0 112000.0 0.21 2674506.0 633000.0 1.26 1.0431 0.8134 3631779 CBKinase1_021846 Oc1ccc(cc1O)C(=O)CSc2nnc([nH]2)c3ccccc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I09 compound treatment 2114244.0 499000.0 0.94 2517724.0 476000.0 0.95 1.3347 1.0 3631780 CBKinase1_021847 CC(=O)c1cccc(NC(=O)CS(=O)(=O)c2ccccc2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I10 compound treatment 2075813.0 460000.0 0.86 2386186.0 345000.0 0.69 1.0978 0.9937 3631781 CBKinase1_021848 OCc1nnn(c1CO)c2ccc(Br)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I11 compound treatment 1955437.0 340000.0 0.64 2479053.0 437000.0 0.87 1.0693 0.988 3631782 CBKinase1_021849 COC(=O)c1cc(NC(=O)CSc2ccccn2)cc(c1)C(=O)OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I12 compound treatment 1831931.0 216000.0 0.41 2656021.0 614000.0 1.23 1.1554 0.8933 3026945 CBKinase1_021850 NS(=O)(=O)c1ccc(NC(=O)CCC2COc3ccccc3O2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I13 compound treatment 1872739.0 257000.0 0.48 2590209.0 549000.0 1.1 1.1166 0.932 3631783 CBKinase1_021851 Clc1cccc2c(cc(nc12)c3ccncc3)C(=O)Nc4ccc(cc4)S(=O)(=O)N5CCOCC5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I14 compound treatment 2063027.0 447000.0 0.84 2271127.0 230000.0 0.46 0.9182 0.9595 3631784 CBKinase1_021852 Cc1nc2sc3CCCCc3c2c4nnc(SCC(=O)Nc5cccc6ccccc56)n14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I15 compound treatment 2100209.0 485000.0 0.91 2716832.0 675000.0 1.35 1.5975 0.9816 3631785 CBKinase1_021853 Cn1cc(CNC(=O)c2cc(nc3ccccc23)c4ccc(Br)cc4)cn1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I16 compound treatment 1947143.0 331000.0 0.62 2069920.0 28300.0 0.06 0.48 0.7682 3631786 CBKinase1_021854 COC(=O)CCSc1nc(SC)nc2sc3COC(C)(C)Cc3c12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I17 compound treatment 1991247.0 376000.0 0.71 2216338.0 175000.0 0.35 0.7455 0.9475 3631787 CBKinase1_021855 CCNS(=O)(=O)c1ccc(NC(=O)c2cc(nc3c(C)c(C)ccc23)c4ccccn4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I18 compound treatment 1760140.0 144000.0 0.27 2159514.0 118000.0 0.24 0.3584 0.9976 3631788 CBKinase1_021856 CCOc1ccc(NC(=O)CSc2nc(N)c3c4CC(C)(C)OCc4sc3n2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I19 compound treatment 1696583.0 80900.0 0.15 2113400.0 71800.0 0.14 0.2089 0.9996 3631789 CBKinase1_021857 Cc1ccccc1c2cc(C(=O)NCCCn3ccnc3)c4cc(Cl)ccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I20 compound treatment 1767789.0 152000.0 0.29 2218587.0 177000.0 0.35 0.452 0.9944 3631790 CBKinase1_021858 CCn1c(SCC(=O)Nc2ccc(cc2)C(=O)C)nc3nc4CCCCc4cc3c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I21 mock treatment 1614874.0 -808.0 0.0 2170883.0 129000.0 0.26 0.1816 0.7029 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I22 mock treatment 1818595.0 203000.0 0.38 2338821.0 297000.0 0.59 0.6894 0.9769 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I23 compound treatment 1193689.0 -422000.0 -0.79 1841114.0 -200000.0 -0.4 -0.8435 -0.9501 3631791 CBKinase1_021859 O=C(NC1CCCCC1)c2c(NC(=O)c3cc(nc4ccccc34)c5cccnc5)sc6CCCc26 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 I24 compound treatment 1202429.0 -413000.0 -0.78 1849500.0 -192000.0 -0.38 -0.8201 -0.9474 3631792 CBKinase1_021860 Cc1cc(C)c2nc(cc(C(=O)NCc3ccco3)c2c1)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J01 compound treatment 1356886.0 -259000.0 -0.49 1138952.0 -903000.0 -1.8 -1.6193 -0.8667 3631793 CBKinase1_021861 NS(=O)(=O)c1ccc(CCNC(=O)c2cc(nc3ccc(Br)cc23)c4ccccn4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J02 compound treatment 1414247.0 -201000.0 -0.38 2140411.0 98800.0 0.2 -0.1278 -0.2995 1338189 CBKinase1_021862 O=S(=O)(c1nc(oc1NCC2CCCO2)c3ccccc3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J03 compound treatment 1481463.0 -134000.0 -0.25 1574276.0 -467000.0 -0.93 -0.8386 -0.8669 3631794 CBKinase1_021863 COCCCNC(=O)c1cc(nc2ccc(Br)cc12)c3ccccn3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J04 compound treatment 1533375.0 -82300.0 -0.15 1786713.0 -255000.0 -0.51 -0.4695 -0.8819 3631795 CBKinase1_021864 Cc1ccccc1c2nc(c(NCc3cccnc3)o2)S(=O)(=O)c4ccc(Cl)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J05 mock treatment 1636391.0 20700.0 0.04 1997286.0 -44300.0 -0.09 -0.0351 -0.3633 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J06 mock treatment 1860823.0 245000.0 0.46 2316219.0 275000.0 0.55 0.7135 0.9962 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J07 compound treatment 471134.0 -1140000.0 -2.15 620812.0 -1420000.0 -2.84 -3.5273 -0.9905 3631796 CBKinase1_021865 COc1cc(Cl)c(cc1OC)C(Nc2ccccn2)c3cc(Cl)c4cccnc4c3O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J08 compound treatment 1904316.0 289000.0 0.54 2136277.0 94700.0 0.19 0.517 0.9007 1873699 CBKinase1_021866 CC(=O)Nc1ccc(OCC(O)Cn2cnc3ccccc23)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J09 compound treatment 1817420.0 202000.0 0.38 2066786.0 25200.0 0.05 0.3034 0.7941 3631797 CBKinase1_021867 Cc1cccc(c1)c2nnc(SCC(=O)Nc3cccc(Br)c3)n2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J10 compound treatment 2009172.0 393000.0 0.74 2104156.0 62600.0 0.13 0.6108 0.8152 3631798 CBKinase1_021868 COc1ccc(NC(=O)CSc2ncnc3c2sc4nc(N5CCOCC5)c6COC(C)(C)Cc6c43)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J11 compound treatment 1467018.0 -149000.0 -0.28 1919446.0 -122000.0 -0.24 -0.37 -0.9978 3631799 CBKinase1_021869 COc1ccccc1NC(=O)CNC(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J12 compound treatment 2210326.0 595000.0 1.12 2060388.0 18800.0 0.04 0.8159 0.7305 3631800 CBKinase1_021870 Cc1cc(OCC(=O)Nc2ccccc2C(=O)NC3CCCCC3)cc(C)c1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J13 compound treatment 1910343.0 295000.0 0.55 2228107.0 187000.0 0.37 0.6547 0.9815 3631801 CBKinase1_021871 CC(=O)Nc1cccc(NC(=O)c2cc(nc3ccc(Br)cc23)c4ccccn4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J14 compound treatment 1941314.0 326000.0 0.61 2329413.0 288000.0 0.58 0.839 0.9995 3631802 CBKinase1_021872 COc1ccccc1NC(=O)CSC2CC(=O)N(C2=O)c3ccc(F)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J15 compound treatment 1858375.0 243000.0 0.46 2103915.0 62300.0 0.12 0.4102 0.8685 3631803 CBKinase1_021873 CC(C)c1cc(C(=O)N2CCOCC2)c(NC(=O)c3cc(nc4ccc(Br)cc34)c5cccnc5)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J16 compound treatment 1971070.0 355000.0 0.67 2290874.0 249000.0 0.5 0.8241 0.9897 3631804 CBKinase1_021874 COc1ccc(cc1)N2C(=O)CC(SCC(=O)Nc3cccc(Br)c3)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J17 compound treatment 1600989.0 -14700.0 -0.03 1994421.0 -47200.0 -0.09 -0.0862 -0.8772 3631805 CBKinase1_021875 Clc1cccc(c1)c2cc(C(=O)NCc3cccnc3)c4ccccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J18 compound treatment 1786682.0 171000.0 0.32 2047364.0 5760.0 0.01 0.2351 0.732 3631806 CBKinase1_021876 Cc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccc(Br)cc3)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J19 compound treatment 1819789.0 204000.0 0.38 1921776.0 -120000.0 -0.24 0.1016 0.2248 3631807 CBKinase1_021877 Cc1ccc2nc(cc(C(=O)Nc3ccc(cc3)S(=O)(=O)NC(C)(C)C)c2c1)c4cccnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J20 compound treatment 1801316.0 186000.0 0.35 1986243.0 -55400.0 -0.11 0.1682 0.46 3631808 CBKinase1_021878 Cc1cccc2c(C)cc(SCC(=O)Nc3cccc(Br)c3)nc12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J21 mock treatment 1532710.0 -83000.0 -0.16 2015832.0 -25800.0 -0.05 -0.1466 -0.8934 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J22 mock treatment 1592872.0 -22800.0 -0.04 2048220.0 6610.0 0.01 -0.0209 -0.4671 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J23 compound treatment 1243068.0 -373000.0 -0.7 1939551.0 -102000.0 -0.2 -0.6389 -0.8768 3631809 CBKinase1_021879 O=C(Nc1cccc(Cn2cccn2)c1)c3cc(nc4ccccc34)c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 J24 compound treatment 1238700.0 -377000.0 -0.71 1469045.0 -573000.0 -1.14 -1.3096 -0.9733 3631810 CBKinase1_021880 COc1cccc2cc(oc12)C(=O)C3=C(O)C(=O)N(C3c4ccccc4)c5cc(C)on5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K01 compound treatment 1439505.0 -176000.0 -0.33 1711393.0 -330000.0 -0.66 -0.7006 -0.949 3631811 CBKinase1_021881 [O-][N+](=O)c1ccc(NC(=O)COc2ccccc2C(=O)Nc3ccccc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K02 compound treatment 1593629.0 -22100.0 -0.04 2107450.0 65800.0 0.13 0.0638 0.4623 3631812 CBKinase1_021882 O=C(CCn1cnc2ccccc2c1=O)Nc3oc(c(c3C#N)c4ccccc4)c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K03 compound treatment 1507884.0 -108000.0 -0.2 2107823.0 66200.0 0.13 -0.0495 -0.2048 3631813 CBKinase1_021883 Clc1cccc(c1)c2nnc(SCC(=O)Nc3ccccc3)n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K04 compound treatment 1669231.0 53500.0 0.1 2079523.0 37900.0 0.08 0.1247 0.9903 3631814 CBKinase1_021884 CC(=O)Nc1ccc(cc1)S(=O)(=O)NC2(C(=O)N(Cc3ccc(F)cc3)C4=C2C(=O)CC(C)(C)C4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K05 compound treatment 1496725.0 -119000.0 -0.22 2236207.0 195000.0 0.39 0.1171 0.2611 3631815 CBKinase1_021885 COc1cc(NC(=O)CS(=O)(=O)c2ccccc2)cc(OC)c1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K06 compound treatment 1698951.0 83300.0 0.16 2394140.0 353000.0 0.7 0.6088 0.8435 3631816 CBKinase1_021886 CCOC(=O)c1ccc(Cn2c(nnc2c3ccccc3)c4ccccc4)o1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K07 mock treatment 1816133.0 200000.0 0.38 2397168.0 356000.0 0.71 0.7686 0.9558 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K08 mock treatment 2000309.0 385000.0 0.72 2570108.0 529000.0 1.06 1.2575 0.9828 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K09 compound treatment 1924673.0 309000.0 0.58 2561110.0 520000.0 1.04 1.1444 0.9622 3631817 CBKinase1_021887 Cc1nnc(SCC(=O)Nc2cccc(F)c2)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K10 compound treatment 1634900.0 19200.0 0.04 2226131.0 185000.0 0.37 0.2863 0.7726 3631818 CBKinase1_021888 CCOC(=O)c1cc(sc1NC(=S)NC(=O)c2ccccc2)C3COc4ccccc4O3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K11 compound treatment 1810862.0 195000.0 0.37 2547184.0 506000.0 1.01 0.9736 0.9058 3631819 CBKinase1_021889 COC(=O)c1ccc(C(=O)OC)c(NC(=O)CSc2ccccn2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K12 compound treatment 2031169.0 415000.0 0.78 2463671.0 422000.0 0.84 1.148 0.9992 3631820 CBKinase1_021890 COC(=O)c1c(NC(=O)CCC(=O)O)sc2COC(C)(C)Cc12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K13 compound treatment 1927795.0 312000.0 0.59 2430959.0 389000.0 0.78 0.9646 0.9902 3631821 CBKinase1_021891 COC(=O)c1c(C)c(C)sc1NC(=O)c2cc(nc3c(C)cc(C)cc23)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K14 compound treatment 1598918.0 -16800.0 -0.03 2260881.0 219000.0 0.44 0.2876 0.6546 3631822 CBKinase1_021892 Cc1ccc(cc1)n2c(=O)c3c4CCCCc4sc3n5c(SCC(=O)c6ccc(F)cc6)nnc25 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K15 mock treatment 1822209.0 207000.0 0.39 2268869.0 227000.0 0.45 0.5953 0.9969 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K16 mock treatment 2013743.0 398000.0 0.75 1805426.0 -236000.0 -0.47 0.1946 0.2202 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K17 compound treatment 1401476.0 -214000.0 -0.4 1826292.0 -215000.0 -0.43 -0.5887 -0.9994 3631823 CBKinase1_021893 COc1cccc(CN2CCN(CC2)C(=O)c3cc(nc4ccc(Cl)cc34)c5ccccn5)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K18 compound treatment 1696362.0 80700.0 0.15 2209957.0 168000.0 0.34 0.345 0.935 3631824 CBKinase1_021894 CCc1nc2sc3CCCc3c2c4nnc(SCC(=O)Nc5ccccc5)n14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K19 compound treatment 1260997.0 -355000.0 -0.67 1546588.0 -495000.0 -0.99 -1.1704 -0.9814 3631825 CBKinase1_021895 CCn1ncc(CN(C)C(=O)c2cc(nc3ccc(Cl)cc23)c4cccnc4)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K20 compound treatment 1286827.0 -329000.0 -0.62 1964583.0 -77000.0 -0.15 -0.5454 -0.8572 3631826 CBKinase1_021896 COc1ccc(NC(=O)Cn2c(=O)n(c3ccc(Cl)cc3)c(=O)c4c5CCCCc5sc24)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K21 compound treatment 1572352.0 -43300.0 -0.08 2292838.0 251000.0 0.5 0.2975 0.5849 3631827 CBKinase1_021897 COC(=O)c1cc(OC)c(OC)cc1NC(=O)c2cc(nc3ccccc23)c4ccc(C)o4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K22 compound treatment 1243633.0 -372000.0 -0.7 1990019.0 -51600.0 -0.1 -0.5668 -0.8028 3631828 CBKinase1_021898 Clc1ccc2nc(cc(C(=O)NCc3ccco3)c2c1)c4cccnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K23 mock treatment 1223461.0 -392000.0 -0.74 1841620.0 -200000.0 -0.4 -0.8033 -0.9588 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 K24 mock treatment 1108616.0 -507000.0 -0.95 1865787.0 -176000.0 -0.35 -0.9216 -0.9082 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L01 compound treatment 1208777.0 -407000.0 -0.76 1665810.0 -376000.0 -0.75 -1.0713 -1.0 3631829 CBKinase1_021899 Cc1ccc2nc(cc(C(=O)Nc3ccc(cc3)S(=O)(=O)N4CCOCC4)c2c1)c5ccccn5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L02 compound treatment 1347660.0 -268000.0 -0.5 1527684.0 -514000.0 -1.03 -1.0821 -0.9461 3631830 CBKinase1_021900 Cc1ccccc1c2nc(c(NCC3CCCO3)o2)S(=O)(=O)c4ccc(Cl)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L03 compound treatment 1448247.0 -167000.0 -0.31 1887705.0 -154000.0 -0.31 -0.4398 -0.9999 3631831 CBKinase1_021901 COCCNC(=O)c1cc(nc2ccc(Br)cc12)c3cccnc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L04 compound treatment 1385111.0 -231000.0 -0.43 1876688.0 -165000.0 -0.33 -0.5392 -0.991 3631832 CBKinase1_021902 Cc1ccccc1c2nc(c(NCc3cccnc3)o2)S(=O)(=O)c4ccc(Br)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L05 compound treatment 1261406.0 -354000.0 -0.67 2042685.0 1080.0 0.0 -0.4688 -0.7048 3631833 CBKinase1_021903 Cc1ccc2nc(cc(C(=O)NCc3cnn(C)c3)c2c1)c4cccnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L06 compound treatment 1297298.0 -318000.0 -0.6 1821904.0 -220000.0 -0.44 -0.7331 -0.9885 1874188 CBKinase1_021904 Clc1ccccc1c2nc(c(NCCN3CCOCC3)o2)S(=O)(=O)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L07 mock treatment 1498861.0 -117000.0 -0.22 2125578.0 84000.0 0.17 -0.0364 -0.1318 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L08 mock treatment 1988621.0 373000.0 0.7 2022261.0 -19300.0 -0.04 0.4677 0.667 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L09 compound treatment 1423038.0 -193000.0 -0.36 2212370.0 171000.0 0.34 -0.0144 -0.0289 3631834 CBKinase1_021905 [O-][N+](=O)c1ccc2C(=O)N(CC(=O)Nc3ccccc3c4ccccc4)C(=O)c2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L10 compound treatment 1507785.0 -108000.0 -0.2 2013153.0 -28500.0 -0.06 -0.1834 -0.8719 3631835 CBKinase1_021906 CCOC(=O)C(C)Sc1ncnc2c1sc3nc(N4CCOCC4)c5COC(C)(C)Cc5c32 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L11 compound treatment 1357565.0 -258000.0 -0.48 1448385.0 -593000.0 -1.19 -1.181 -0.9221 3631836 CBKinase1_021907 O=C(CCN1C(=O)c2ccccc2C1=O)Nc3ccc(cc3)c4nc5ccccc5s4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L12 compound treatment 1335216.0 -280000.0 -0.53 2025278.0 -16300.0 -0.03 -0.3954 -0.7495 3631837 CBKinase1_021908 Cc1cccc(C)c1OCC(=O)Nc2ccccc2C(=O)NC3CCCCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L13 compound treatment 1185105.0 -431000.0 -0.81 1390950.0 -651000.0 -1.3 -1.4911 -0.9738 3631838 CBKinase1_021909 NS(=O)(=O)c1ccc(CCNC(=O)c2cc(nc3ccc(Cl)cc23)c4cccnc4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L14 compound treatment 1856153.0 240000.0 0.45 1820176.0 -221000.0 -0.44 0.0063 0.0099 3631839 CBKinase1_021910 COc1ccccc1NC(=O)CSC2CC(=O)N(C2=O)c3ccc(C)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L15 mock treatment 1728990.0 113000.0 0.21 1724008.0 -318000.0 -0.63 -0.2984 -0.4458 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L16 mock treatment 1422475.0 -193000.0 -0.36 2179909.0 138000.0 0.28 -0.061 -0.1338 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L17 compound treatment 1314964.0 -301000.0 -0.56 1861823.0 -180000.0 -0.36 -0.6533 -0.9762 3631840 CBKinase1_021911 Clc1ccc2nc(cc(C(=O)NCCCN3CCCC3=O)c2c1)c4cccnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L18 compound treatment 1634842.0 19200.0 0.04 1834544.0 -207000.0 -0.41 -0.2672 -0.6432 3631841 CBKinase1_021912 COc1cccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccc(Br)cc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L19 compound treatment 1601334.0 -14300.0 -0.03 2070362.0 28800.0 0.06 0.0216 0.3402 3631842 CBKinase1_021913 NS(=O)(=O)c1ccc(CCNC(=O)c2cc(nc3ccccc23)c4cccs4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L20 compound treatment 1425668.0 -190000.0 -0.36 1479460.0 -562000.0 -1.12 -1.0467 -0.8879 3631843 CBKinase1_021914 Cc1ccc(Cl)cc1NC(=O)CSc2cc(C)c3cccc(C)c3n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L21 compound treatment 1178278.0 -437000.0 -0.82 2127113.0 85500.0 0.17 -0.4598 -0.5482 3631844 CBKinase1_021915 COc1ccccc1CCNC(=O)c2cc(nc3c(C)c(Cl)ccc23)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L22 compound treatment 1341739.0 -274000.0 -0.51 1994775.0 -46800.0 -0.09 -0.4298 -0.8223 3631845 CBKinase1_021916 COCCn1c(=O)n(CC(=O)N)c2sc3CCCCc3c2c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L23 mock treatment 1344874.0 -271000.0 -0.51 1902179.0 -139000.0 -0.28 -0.5565 -0.9599 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 L24 mock treatment 1179115.0 -437000.0 -0.82 2020996.0 -20600.0 -0.04 -0.6087 -0.7417 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M01 compound treatment 1497538.0 -118000.0 -0.22 1597907.0 -444000.0 -0.89 -0.7839 -0.8575 3631846 CBKinase1_021917 COc1cccc(NC(=O)COc2ccccc2C(=O)N)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M02 compound treatment 1522997.0 -92700.0 -0.17 1857475.0 -184000.0 -0.37 -0.3833 -0.9415 3631847 CBKinase1_021918 O=C(CCn1cnc2ccccc2c1=O)Nc3sc4CCCc4c3C#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M03 compound treatment 1584928.0 -30800.0 -0.06 1612882.0 -429000.0 -0.86 -0.6467 -0.753 3631848 CBKinase1_021919 Cc1ccc2nsnc2c1S(=O)(=O)NCc3ccncc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M04 compound treatment 1591309.0 -24400.0 -0.05 1879433.0 -162000.0 -0.32 -0.2616 -0.799 3631849 CBKinase1_021920 Cc1nnc(NC2(C(=O)Nc3c2c(=O)n(C)c(=O)n3C)C(F)(F)F)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M05 compound treatment 1589382.0 -26300.0 -0.05 1702047.0 -340000.0 -0.68 -0.5148 -0.7565 3631850 CBKinase1_021921 Oc1ccccc1NC(=O)CS(=O)(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M06 compound treatment 1391491.0 -224000.0 -0.42 1859869.0 -182000.0 -0.36 -0.5545 -0.9973 3631851 CBKinase1_021922 O=C(Cn1c(nc2ccccc12)S(=O)(=O)Cc3ccccc3)N4CCOCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M07 compound treatment 1557486.0 -58200.0 -0.11 1895993.0 -146000.0 -0.29 -0.283 -0.9105 3631852 CBKinase1_021923 COc1cc(Cl)c(C)cc1NC(=O)CSc2nnnn2c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M08 compound treatment 1507778.0 -108000.0 -0.2 1778093.0 -264000.0 -0.53 -0.5157 -0.9138 3631853 CBKinase1_021924 Clc1cc(NC(=O)CSc2nnnn2c3cccc4ccccc34)ccc1N5CCOCC5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M09 mock treatment 1651858.0 36200.0 0.07 1927055.0 -115000.0 -0.23 -0.1139 -0.4768 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M10 mock treatment 1445396.0 -170000.0 -0.32 1931220.0 -110000.0 -0.22 -0.3821 -0.9836 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M11 compound treatment 1691806.0 76100.0 0.14 1955474.0 -86100.0 -0.17 -0.0207 -0.0924 3631854 CBKinase1_021925 COc1cc(NC(=O)CSc2nnc(o2)c3ccncc3)cc(OC)c1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M12 compound treatment 1484619.0 -131000.0 -0.25 1973647.0 -68000.0 -0.14 -0.27 -0.9608 3631855 CBKinase1_021926 OC(=O)CCc1nn2cnc3sc4CCCCc4c3c2nc1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M13 mock treatment 1556560.0 -59100.0 -0.11 2017446.0 -24200.0 -0.05 -0.1126 -0.9305 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M14 mock treatment 1440442.0 -175000.0 -0.33 1796970.0 -245000.0 -0.49 -0.5784 -0.9814 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M15 compound treatment 1576877.0 -38800.0 -0.07 1694583.0 -347000.0 -0.69 -0.542 -0.7771 3631856 CBKinase1_021927 COc1ccc(cc1OC)C(C)NC(=O)c2cc(nc3ccc(Cl)cc23)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M16 compound treatment 1316031.0 -300000.0 -0.56 1387605.0 -654000.0 -1.31 -1.3221 -0.929 3631857 CBKinase1_021928 CC1(C)Cc2c(CO1)sc3nc(SCc4ccccc4)nc(NCc5ccco5)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M17 compound treatment 1455889.0 -160000.0 -0.3 1548975.0 -493000.0 -0.98 -0.9083 -0.8825 3631858 CBKinase1_021929 Brc1ccc2nc(cc(C(=O)NCCCN3CCCC3=O)c2c1)c4cccnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M18 compound treatment 1519391.0 -96300.0 -0.18 1921414.0 -120000.0 -0.24 -0.2977 -0.9902 3631859 CBKinase1_021930 CCc1nc2sc3CCCc3c2c4nnc(SCC(=O)OC)n14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M19 compound treatment 1552447.0 -63200.0 -0.12 1162605.0 -879000.0 -1.76 -1.3262 -0.7532 3631860 CBKinase1_021931 COC(=O)c1cc(sc1NC(=O)c2cc(nc3ccccc23)c4cccnc4)c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M20 compound treatment 1026438.0 -589000.0 -1.11 1143671.0 -898000.0 -1.79 -2.0512 -0.973 3631861 CBKinase1_021932 COc1ccc(NC(=O)CC(c2ccco2)c3ccccc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M21 compound treatment 1341277.0 -274000.0 -0.52 1620415.0 -421000.0 -0.84 -0.9595 -0.9722 3631862 CBKinase1_021933 COc1ccccc1CNC(=O)c2cc(nc3c(Cl)cccc23)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M22 compound treatment 1317511.0 -298000.0 -0.56 1587994.0 -454000.0 -0.91 -1.0369 -0.9731 3631863 CBKinase1_021934 Clc1cccc(c1)c2cc(C(=O)NCc3ccco3)c4ccccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M23 compound treatment 1033565.0 -582000.0 -1.09 1450469.0 -591000.0 -1.18 -1.6082 -0.9992 3631864 CBKinase1_021935 COC(=O)c1cc(Cc2ccccc2)sc1NC(=O)c3cc(nc4ccccc34)c5cccnc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 M24 compound treatment 1125467.0 -490000.0 -0.92 1567488.0 -474000.0 -0.95 -1.3208 -0.9999 3631865 CBKinase1_021936 NS(=O)(=O)c1ccc(CNC(=O)c2cc(nc3ccc(Br)cc23)c4ccccn4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N01 compound treatment 1340101.0 -276000.0 -0.52 1555063.0 -487000.0 -0.97 -1.0535 -0.9564 3631866 CBKinase1_021937 Cc1ccc(o1)c2cc(C(=O)NCc3ccc(cc3)S(=O)(=O)N)c4cc(Br)ccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N02 compound treatment 1398288.0 -217000.0 -0.41 1697178.0 -344000.0 -0.69 -0.7754 -0.9689 3631867 CBKinase1_021938 Cc1ccc(cc1)S(=O)(=O)c2nc(oc2NCCN3CCOCC3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N03 compound treatment 1117596.0 -498000.0 -0.94 1203138.0 -838000.0 -1.68 -1.8462 -0.962 3631868 CBKinase1_021939 COc1ccc(OC)c(c1)c2cc(C(=O)NC(C)c3ccc(OC)c(OC)c3)c4ccccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N04 compound treatment 1443591.0 -172000.0 -0.32 1776502.0 -265000.0 -0.53 -0.6031 -0.9718 3631869 CBKinase1_021940 O=S(=O)(c1nc(oc1NCc2ccco2)c3ccco3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N05 compound treatment 1245698.0 -370000.0 -0.69 1666710.0 -375000.0 -0.75 -1.021 -0.9993 3631870 CBKinase1_021941 NS(=O)(=O)c1ccc(CCNC(=O)c2cc(nc3ccc(Br)cc23)c4cccnc4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N06 compound treatment 1030805.0 -585000.0 -1.1 1792890.0 -249000.0 -0.5 -1.1279 -0.9358 1533989 CBKinase1_021942 Clc1ccccc1c2nc(c(NCc3cccnc3)o2)S(=O)(=O)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N07 compound treatment 1429766.0 -186000.0 -0.35 1591526.0 -450000.0 -0.9 -0.8829 -0.915 3631871 CBKinase1_021943 Cc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(Br)c3)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N08 compound treatment 1259065.0 -357000.0 -0.67 1677283.0 -364000.0 -0.73 -0.9883 -0.9991 3631872 CBKinase1_021944 CC(=O)Nc1ccc(OCC(O)Cn2ccnc2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N09 mock treatment 1458694.0 -157000.0 -0.29 1798095.0 -244000.0 -0.49 -0.5525 -0.9711 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N10 mock treatment 1409719.0 -206000.0 -0.39 1769058.0 -273000.0 -0.54 -0.6586 -0.9859 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N11 compound treatment 1428638.0 -187000.0 -0.35 1731094.0 -311000.0 -0.62 -0.6871 -0.9636 3631873 CBKinase1_021945 OC(=O)c1cc(O)ccc1NC(=O)COc2ccc(I)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N12 compound treatment 1401571.0 -214000.0 -0.4 1727346.0 -314000.0 -0.63 -0.7284 -0.9767 3631874 CBKinase1_021946 Brc1c(OCC(=O)Nc2ccccc2C(=O)NC3CCCCC3)ccc4ccccc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N13 mock treatment 1424481.0 -191000.0 -0.36 1580771.0 -461000.0 -0.92 -0.9051 -0.9156 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N14 mock treatment 1486881.0 -129000.0 -0.24 1485854.0 -556000.0 -1.11 -0.9564 -0.8413 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N15 compound treatment 1764677.0 149000.0 0.28 1578138.0 -463000.0 -0.93 -0.4572 -0.4725 3631875 CBKinase1_021947 Cc1sc(NC(=O)c2cc(nc3ccc(Cl)cc23)c4ccccn4)c(C(=O)N)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N16 compound treatment 1643613.0 27900.0 0.05 1823842.0 -218000.0 -0.44 -0.2707 -0.6175 3631876 CBKinase1_021948 Cc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3cc(Cl)cc(Cl)c3)cc1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N17 compound treatment 1532589.0 -83100.0 -0.16 1682213.0 -359000.0 -0.72 -0.6182 -0.8411 3631877 CBKinase1_021949 Cc1ccc(cc1)c2cc(C(=O)NCCCN3CCOCC3)c4cc(Br)ccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N18 compound treatment 1579777.0 -35900.0 -0.07 2357207.0 316000.0 0.63 0.3984 0.628 3631878 CBKinase1_021950 COC(=O)c1ccc(cc1)N2C(=O)CC(SCC(=O)Nc3ccc(C)c(C)c3)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N19 compound treatment 1524886.0 -90800.0 -0.17 1683645.0 -358000.0 -0.72 -0.6264 -0.8517 3631879 CBKinase1_021951 Cc1sc(NC(=O)c2cc(nc3ccccc23)c4cccnc4)c(C(=O)NC5CCCCC5)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N20 compound treatment 1442024.0 -174000.0 -0.33 1650436.0 -391000.0 -0.78 -0.7834 -0.9248 3631880 CBKinase1_021952 Cc1nn(c(C)c1SCC(=O)Nc2ccc(F)cc2)c3nnc(C)c(=O)[nH]3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N21 compound treatment 1273341.0 -342000.0 -0.64 1483266.0 -558000.0 -1.12 -1.2435 -0.9656 3631881 CBKinase1_021953 Cc1ccc(o1)c2cc(C(=O)NCc3ccco3)c4cc(Br)ccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N22 compound treatment 1325732.0 -290000.0 -0.54 1872656.0 -169000.0 -0.34 -0.6237 -0.9736 3631882 CBKinase1_021954 COC(=O)Cn1c(=O)n(Cc2ccco2)c(=O)c3c4CCCCc4sc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N23 compound treatment 1268165.0 -348000.0 -0.65 1341194.0 -700000.0 -1.4 -1.4512 -0.9396 3631883 CBKinase1_021955 Clc1ccc2nc(cc(C(=O)Nc3cccc(Cn4cccn4)c3)c2c1)c5cccnc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 N24 compound treatment 1158320.0 -457000.0 -0.86 1516909.0 -525000.0 -1.05 -1.3487 -0.9951 3631884 CBKinase1_021956 COc1cccc2cc(oc12)C(=O)C3=C(O)C(=O)N(C3c4cccs4)c5cc(C)on5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O01 compound treatment 993362.0 -622000.0 -1.17 1016695.0 -1020000.0 -2.05 -2.2746 -0.9645 3631885 CBKinase1_021957 COc1ccccc1N2CC(CC2=O)C(=O)Nc3cccc(c3)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O02 compound treatment 1070737.0 -545000.0 -1.02 1382256.0 -659000.0 -1.32 -1.6553 -0.9922 3631886 CBKinase1_021958 O=C(Cn1cnc2ccccc2c1=O)Nc3ccc(cc3)S(=O)(=O)N4CCOCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O03 compound treatment 1259085.0 -357000.0 -0.67 1066686.0 -975000.0 -1.95 -1.8512 -0.8985 3631887 CBKinase1_021959 CCCn1c2ccccc2c3nnc(Sc4ccc5nsnc5c4[N+](=O)[O-])nc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O04 compound treatment 973407.0 -642000.0 -1.21 1378295.0 -663000.0 -1.33 -1.7901 -0.9989 3631888 CBKinase1_021960 CC(=O)c1ccc(OC(=O)C(CCS(=O)(=O)C)N2C(=O)c3ccccc3C2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O05 compound treatment 1287754.0 -328000.0 -0.62 1427746.0 -614000.0 -1.23 -1.3029 -0.9491 3631889 CBKinase1_021961 CCOC(=O)CSc1nc2ccc(Br)cc2c(=O)n1c3ccccc3OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O06 compound treatment 1141155.0 -475000.0 -0.89 1354566.0 -687000.0 -1.37 -1.6009 -0.9781 3631890 CBKinase1_021962 Cc1ccc(NC(=O)CSc2nnnn2c3ccc(Cl)c(c3)C(=O)O)cc1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O07 compound treatment 1164532.0 -451000.0 -0.85 1481610.0 -560000.0 -1.12 -1.3903 -0.9905 3631891 CBKinase1_021963 COc1cc(NC(=O)CSc2nnnn2c3ccccc3)cc(OC)c1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O08 compound treatment 1383503.0 -232000.0 -0.44 1679502.0 -362000.0 -0.72 -0.82 -0.9705 3631892 CBKinase1_021964 COc1ccc(Cl)cc1NC(=O)CSc2nnc([nH]2)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O09 compound treatment 1482527.0 -133000.0 -0.25 1499798.0 -542000.0 -1.08 -0.9425 -0.848 3631893 CBKinase1_021965 COc1cc(NC(=O)CSc2nnc(C)s2)cc(OC)c1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O10 compound treatment 1324514.0 -291000.0 -0.55 1591022.0 -451000.0 -0.9 -1.0233 -0.9714 3631894 CBKinase1_021966 FC(F)(F)c1cnc(NC(=O)CCC2COc3ccccc3O2)c(Cl)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O11 mock treatment 1196682.0 -419000.0 -0.79 1077447.0 -964000.0 -1.93 -1.9188 -0.9219 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O12 mock treatment 1349512.0 -266000.0 -0.5 1299736.0 -742000.0 -1.48 -1.4018 -0.8959 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O13 compound treatment 1249103.0 -367000.0 -0.69 1283791.0 -758000.0 -1.51 -1.5576 -0.9363 3631895 CBKinase1_021967 Cc1cc(C)c2nc(cc(C(=O)Nc3sc(Cc4ccccc4)cc3C(=O)N)c2c1)c5cccnc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O14 compound treatment 1026761.0 -589000.0 -1.11 1404288.0 -637000.0 -1.27 -1.6825 -0.9975 3631896 CBKinase1_021968 CCC1(C)Cc2c(CO1)sc3nc(SCC(=O)Nc4ccc(Cl)cc4)nc(N)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O15 compound treatment 1078568.0 -537000.0 -1.01 1008217.0 -1030000.0 -2.07 -2.1735 -0.9456 3631897 CBKinase1_021969 Cc1ccc2nc(cc(C(=O)NCc3ccccn3)c2c1)c4ccncc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O16 compound treatment 1119842.0 -496000.0 -0.93 1345318.0 -696000.0 -1.39 -1.6423 -0.9809 3631898 CBKinase1_021970 CCCSc1nc(NCCO)c2c3CC(C)(CC)OCc3sc2n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O17 compound treatment 1507287.0 -108000.0 -0.2 1344764.0 -697000.0 -1.39 -1.1287 -0.8019 3631899 CBKinase1_021971 CCn1cc(CNC(=O)c2cc(nc3ccc(Br)cc23)c4cccnc4)c(C)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O18 compound treatment 1258365.0 -357000.0 -0.67 1419916.0 -622000.0 -1.24 -1.353 -0.9581 3631900 CBKinase1_021972 COC(=O)CSc1nnc2c3c4CCCCc4sc3nc(c5ccccc5Cl)n12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O19 compound treatment 1136763.0 -479000.0 -0.9 1395543.0 -646000.0 -1.29 -1.5488 -0.9843 3631901 CBKinase1_021973 CC(=O)Nc1cccc(NC(=O)c2cc(nc3ccccc23)c4ccc(C)o4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O20 compound treatment 779547.0 -836000.0 -1.57 940757.0 -1100000.0 -2.2 -2.6658 -0.9863 3631902 CBKinase1_021974 CC(C)C1CC(CCNCc2ccco2)(CCO1)c3ccc(C)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O21 compound treatment 878797.0 -737000.0 -1.38 1091993.0 -950000.0 -1.9 -2.3203 -0.9879 3631903 CBKinase1_021975 COc1ccc(NC(=O)c2cc(nc3c(C)cc(C)cc23)c4ccccn4)c(c1)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O22 compound treatment 1293031.0 -323000.0 -0.61 752134.0 -1290000.0 -2.58 -2.2507 -0.8501 3631904 CBKinase1_021976 Clc1cccc2c(cc(nc12)c3ccccn3)C(=O)NCc4cccnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O23 compound treatment 960728.0 -655000.0 -1.23 1170658.0 -871000.0 -1.74 -2.1003 -0.9855 3631905 CBKinase1_021977 Brc1ccc2nc(cc(C(=O)NCc3ccco3)c2c1)c4cccnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 O24 compound treatment 1007839.0 -608000.0 -1.14 1051499.0 -990000.0 -1.98 -2.2062 -0.9658 3631906 CBKinase1_021978 CN(C)CCNC(=O)c1cc(nc2ccc(Br)cc12)c3ccc(C)o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P01 compound treatment 826938.0 -789000.0 -1.48 894140.0 -1150000.0 -2.29 -2.6687 -0.9776 3631907 CBKinase1_021979 Cc1ccc2nc(cc(C(=O)NCc3ccccn3)c2c1)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P02 compound treatment 964529.0 -651000.0 -1.22 930197.0 -1110000.0 -2.22 -2.4351 -0.9604 3631908 CBKinase1_021980 Fc1ccc(cc1)c2nc(c(NCCN3CCOCC3)o2)S(=O)(=O)c4ccc(F)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P03 compound treatment 906489.0 -709000.0 -1.33 1150962.0 -891000.0 -1.78 -2.2002 -0.9898 3631909 CBKinase1_021981 Cc1ccc(o1)c2cc(C(=O)Nc3sc(C)c(c3C(=O)N)c4ccccc4)c5ccccc5n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P04 compound treatment 909065.0 -707000.0 -1.33 1133044.0 -909000.0 -1.82 -2.2221 -0.9881 3631910 CBKinase1_021982 O=S(=O)(c1nc(oc1NCC2CCCO2)c3ccco3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P05 compound treatment 914768.0 -701000.0 -1.32 1104189.0 -937000.0 -1.87 -2.2553 -0.9851 3631911 CBKinase1_021983 COc1ccc(cc1OC)c2csc(NC(=O)c3cc(nc4ccccc34)c5ccc(C)o5)c2C#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P06 compound treatment 939393.0 -676000.0 -1.27 1233768.0 -808000.0 -1.61 -2.0395 -0.9929 1874195 CBKinase1_021984 Cc1ccc(cc1)S(=O)(=O)c2nc(oc2NCC3CCCO3)c4ccccc4Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P07 compound treatment 1030179.0 -586000.0 -1.1 1198174.0 -843000.0 -1.69 -1.9693 -0.9785 3631912 CBKinase1_021985 Fc1cccc(NC(=O)CSc2nnc(o2)c3ccccc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P08 compound treatment 1028785.0 -587000.0 -1.1 1278223.0 -763000.0 -1.53 -1.858 -0.9872 3631913 CBKinase1_021986 Cc1cc2ncn(CC(O)COc3ccc(N)cc3)c2cc1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P09 compound treatment 1147598.0 -468000.0 -0.88 1411926.0 -630000.0 -1.26 -1.5113 -0.9846 3631914 CBKinase1_021987 CCn1c(SCC(=O)Nc2cccc(Br)c2)nnc1c3ccc(Cl)cc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P10 compound treatment 992287.0 -623000.0 -1.17 1131488.0 -910000.0 -1.82 -2.1138 -0.9773 3631915 CBKinase1_021988 CC1(C)Cc2c(CO1)c(nc3sc4c(NCc5ccco5)ncnc4c23)N6CCCC6 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P11 mock treatment 1042309.0 -573000.0 -1.08 1263380.0 -778000.0 -1.56 -1.861 -0.9838 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P12 mock treatment 1172561.0 -443000.0 -0.83 1025183.0 -1020000.0 -2.03 -2.0247 -0.9223 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P13 compound treatment 975499.0 -640000.0 -1.2 1079546.0 -962000.0 -1.92 -2.2095 -0.9744 3631916 CBKinase1_021989 Cc1ccc(o1)c2cc(C(=O)NCCCn3ccnc3)c4cc(Br)ccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P14 compound treatment 1055807.0 -560000.0 -1.05 1218263.0 -823000.0 -1.65 -1.9068 -0.9765 3631917 CBKinase1_021990 COc1cccc(NC(=O)CSC2CC(=O)N(C2=O)c3cc(C)cc(C)c3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P15 compound treatment 865602.0 -750000.0 -1.41 1094331.0 -947000.0 -1.89 -2.3345 -0.9894 3631918 CBKinase1_021991 Cc1c(Cl)ccc2c(cc(nc12)c3ccccn3)C(=O)NCCN4CCCCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P16 compound treatment 987669.0 -628000.0 -1.18 1107493.0 -934000.0 -1.87 -2.1538 -0.9754 3631919 CBKinase1_021992 Fc1ccccc1NC(=O)CSC2CC(=O)N(C2=O)c3cc(Cl)cc(Cl)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P17 compound treatment 1013422.0 -602000.0 -1.13 1266611.0 -775000.0 -1.55 -1.8948 -0.988 3631920 CBKinase1_021993 COc1ccc(CCNC(=O)c2cc(nc3c(Cl)cccc23)c4ccncc4)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P18 compound treatment 1058599.0 -557000.0 -1.05 1050518.0 -991000.0 -1.98 -2.1402 -0.9554 3631921 CBKinase1_021994 COC(=O)c1ccc(cc1)N2C(=O)CC(SCC(=O)Nc3ccc(C)c(Cl)c3)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P19 compound treatment 877198.0 -738000.0 -1.39 1094666.0 -947000.0 -1.89 -2.3186 -0.9883 3631922 CBKinase1_021995 CCCc1ccc(cc1)c2cc(C(=O)NCc3cccnc3)c4ccccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P20 compound treatment 846579.0 -769000.0 -1.44 1002235.0 -1040000.0 -2.08 -2.4899 -0.9842 3631923 CBKinase1_021996 CC(C)c1ccc(NC(=O)CSc2c(C)nn(c2C)c3nnc(C)c(=O)[nH]3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P21 compound treatment 338228.0 -1280000.0 -2.4 411573.0 -1630000.0 -3.26 -3.9995 -0.9886 3631924 CBKinase1_021997 CNS(=O)(=O)c1ccc(NC(=O)c2cc(nc3ccc(Br)cc23)c4cccnc4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P22 compound treatment 871889.0 -744000.0 -1.4 1138724.0 -903000.0 -1.8 -2.2634 -0.992 3631925 CBKinase1_021998 COc1ccc(OC)c(c1)S(=O)(=O)Nc2cc3c(C(=O)C)c(C)oc3c4ccccc24 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P23 compound treatment 903543.0 -712000.0 -1.34 1003397.0 -1040000.0 -2.08 -2.4126 -0.9774 3631926 CBKinase1_021999 COc1ccc(cc1OC)C(C)NC(=O)c2cc(nc3ccc(Br)cc23)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2392 P24 compound treatment 910999.0 -705000.0 -1.32 944545.0 -1100000.0 -2.19 -2.4859 -0.9707 3631927 CBKinase1_022000 COc1ccc(OC)c(c1)S(=O)(=O)Nc2ccc(O)c(Sc3nc4ccccc4s3)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A01 compound treatment 1193497.0 -638000.0 -1.2 1132947.0 -562000.0 -1.12 -1.6404 -0.9995 3631928 CBKinase1_022001 CC(C)(C)Nc1nc(SCC(=O)Nc2ccccc2Cl)nc(n1)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A02 compound treatment 1391775.0 -439000.0 -0.82 1188764.0 -506000.0 -1.01 -1.2983 -0.9949 3631929 CBKinase1_022002 COc1ccc(NC(=O)C(C)N(c2ccc(C)c(C)c2)S(=O)(=O)C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A03 compound treatment 1123742.0 -707000.0 -1.33 970805.0 -724000.0 -1.45 -1.9621 -0.9991 3631930 CBKinase1_022003 COc1ccc(NC(=O)CSc2nnc3n4ncnc4c5c6CC(C)(C)OCc6sc5n23)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A04 compound treatment 1381269.0 -450000.0 -0.84 1249650.0 -445000.0 -0.89 -1.2262 -0.9997 3631931 CBKinase1_022004 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)Nc2c(C)cccc2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A05 compound treatment 1465427.0 -366000.0 -0.69 1328506.0 -366000.0 -0.73 -1.003 -0.9995 1206753 CBKinase1_022005 Cc1sc(NC(=O)COc2ccc3c(C)cc(=O)oc3c2)c(C#N)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A06 compound treatment 1446667.0 -384000.0 -0.72 1204051.0 -491000.0 -0.98 -1.2038 -0.9886 3631932 CBKinase1_022006 COc1ccc(C)cc1S(=O)(=O)NCc2ccccn2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A07 compound treatment 1427204.0 -404000.0 -0.76 1364692.0 -330000.0 -0.66 -1.0026 -0.9976 3631933 CBKinase1_022007 CCOC(=O)c1c(NC(=S)NC(=O)c2ccccc2Br)scc1c3ccc(C)o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A08 compound treatment 1652005.0 -179000.0 -0.34 774326.0 -920000.0 -1.84 -1.5385 -0.8227 3631934 CBKinase1_022008 OCCCN1C(c2c(oc3ccccc3c2=O)C1=O)c4cccc(Oc5ccccc5)c4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A09 compound treatment 1654501.0 -177000.0 -0.33 1268831.0 -426000.0 -0.85 -0.8364 -0.9155 3631935 CBKinase1_022009 CC(C)(O)C#Cc1ccccc1C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A10 compound treatment 1313483.0 -518000.0 -0.97 1167441.0 -527000.0 -1.05 -1.4323 -0.9992 3631936 CBKinase1_022010 Cc1c(oc2ccc(F)cc12)C(=O)Nc3sc4CCCc4c3C(=O)NCCc5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A11 compound treatment 1840682.0 9600.0 0.02 1534074.0 -161000.0 -0.32 -0.2143 -0.6664 3631937 CBKinase1_022011 CCCCn1c(C)c(C(=O)C)c2c(OCC(=O)O)c(Cl)c(Cl)c(Cl)c12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A12 compound treatment 1527890.0 -303000.0 -0.57 1558655.0 -136000.0 -0.27 -0.5948 -0.9429 3631938 CBKinase1_022012 Cc1n[nH]c(C)c1SCC(=O)Nc2cc(C)ccc2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A13 mock treatment 1712077.0 -119000.0 -0.22 1359918.0 -335000.0 -0.67 -0.6312 -0.8946 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A14 mock treatment 1834038.0 2960.0 0.01 1426173.0 -269000.0 -0.54 -0.3756 -0.6997 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A15 compound treatment 1739367.0 -91700.0 -0.17 1597770.0 -97000.0 -0.19 -0.2588 -0.9983 3631939 CBKinase1_022013 COc1cc2c(cc1NC(=O)CCCN3C(=O)CCC3=O)oc4ccccc42 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A16 compound treatment 1640014.0 -191000.0 -0.36 1271326.0 -423000.0 -0.85 -0.8521 -0.927 1599411 CBKinase1_022014 Cc1ccc(o1)C(=O)CC2(O)C(=O)N(CC=C)c3ccccc32 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A17 compound treatment 1918539.0 87500.0 0.16 887679.0 -807000.0 -1.61 -1.0245 -0.6319 3631940 CBKinase1_022015 CN(CC(=O)Nc1ccccc1[N+](=O)[O-])S(=O)(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A18 compound treatment 1652099.0 -179000.0 -0.34 1442541.0 -252000.0 -0.5 -0.594 -0.9806 3631941 CBKinase1_022016 CC(N(c1ccc(C)c(C)c1)S(=O)(=O)C)C(=O)Nc2cc(Cl)ccc2Oc3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A19 compound treatment 1614193.0 -217000.0 -0.41 1360147.0 -335000.0 -0.67 -0.7608 -0.9717 3631942 CBKinase1_022017 CN(CC(=O)Nc1ccncc1)S(=O)(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A20 compound treatment 1363704.0 -467000.0 -0.88 1686658.0 -8090.0 -0.02 -0.6319 -0.72 3631943 CBKinase1_022018 COc1cc(c(OC)cc1Cl)S(=O)(=O)NCC2CCCO2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A21 compound treatment 1293932.0 -537000.0 -1.01 1278158.0 -417000.0 -0.83 -1.3018 -0.9955 3631944 CBKinase1_022019 COc1cc(ccc1NC(=O)CN(C)S(=O)(=O)c2ccccc2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A22 compound treatment 1395591.0 -435000.0 -0.82 1691134.0 -3620.0 -0.01 -0.5832 -0.7133 3631945 CBKinase1_022020 COc1ccc(OC)c(NC(=O)C(C)N(c2ccc(C)c(C)c2)S(=O)(=O)C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A23 compound treatment 1395438.0 -436000.0 -0.82 1420306.0 -274000.0 -0.55 -0.9662 -0.9811 3631946 CBKinase1_022021 CN(Cc1nc(no1)c2cccc(c2)[N+](=O)[O-])S(=O)(=O)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 A24 compound treatment 996777.0 -834000.0 -1.57 1375054.0 -320000.0 -0.64 -1.5593 -0.9218 3631947 CBKinase1_022022 COc1ccc(NC(=O)C(C)Oc2cccc(Br)c2)c(c1)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B01 compound treatment 1034606.0 -796000.0 -1.5 1372224.0 -323000.0 -0.64 -1.5131 -0.9293 3631948 CBKinase1_022023 Cc1c(NC(=O)CCN2C(=O)c3ccccc3C2=O)cccc1C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B02 compound treatment 1811694.0 -19400.0 -0.04 1339759.0 -355000.0 -0.71 -0.5274 -0.7424 3631949 CBKinase1_022024 FC(F)(F)c1cc(nc(SCC(=O)c2ccccc2)n1)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B03 compound treatment 2000318.0 169000.0 0.32 1838537.0 144000.0 0.29 0.4279 0.9987 3631950 CBKinase1_022025 O=C(OCc1cccc(c1)C(=O)c2ccccc2)c3ccc(Oc4ccc(C#N)c(C#N)c4)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B04 compound treatment 2096824.0 266000.0 0.5 1372587.0 -322000.0 -0.64 -0.1025 -0.1259 3631951 CBKinase1_022026 COC(=O)c1ccc(C(=O)OC)c(NC(=O)CSc2nc(C)cc(C)n2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B05 compound treatment 1489782.0 -341000.0 -0.64 1172155.0 -523000.0 -1.04 -1.1916 -0.9725 3631952 CBKinase1_022027 COc1cc(NC(=O)COc2cc(C)c(Cl)c(C)c2)c(cc1OC)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B06 compound treatment 1314316.0 -517000.0 -0.97 1393843.0 -301000.0 -0.6 -1.1113 -0.9736 3631953 CBKinase1_022028 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)Nc2cccc(c2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B07 compound treatment 1391586.0 -439000.0 -0.83 1465535.0 -229000.0 -0.46 -0.9074 -0.9615 3631954 CBKinase1_022029 Cn1c(SCC(=O)Nc2cccc(F)c2)nnc1c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B08 compound treatment 1920957.0 89900.0 0.17 1482722.0 -212000.0 -0.42 -0.1803 -0.3954 3631955 CBKinase1_022030 Cn1c(SCC(=O)Nc2ccc(Cl)cc2)nc3sc4CCCCc4c3c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B09 compound treatment 1642913.0 -188000.0 -0.35 1255284.0 -439000.0 -0.88 -0.8709 -0.9199 3631956 CBKinase1_022031 CCn1c(SCC(=O)c2ccc(OC)cc2)nnc1c3ccc(C)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B10 compound treatment 2266354.0 435000.0 0.82 1824573.0 130000.0 0.26 0.7613 0.8879 3631957 CBKinase1_022032 OCc1cc(Cl)ccc1OCC(=O)Nc2ccccc2F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B11 compound treatment 1558931.0 -272000.0 -0.51 1302880.0 -392000.0 -0.78 -0.9151 -0.9786 3631958 CBKinase1_022033 COc1cccc2cc(oc12)c3nnc(SCC(=O)c4ccccc4)n3C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B12 compound treatment 1547261.0 -284000.0 -0.53 1337934.0 -357000.0 -0.71 -0.881 -0.9897 3631959 CBKinase1_022034 CCOC(=O)c1sc(NC(=O)CSc2nc(C)cc(n2)C(F)(F)F)c(C#N)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B13 mock treatment 1336170.0 -495000.0 -0.93 1288496.0 -406000.0 -0.81 -1.2311 -0.9977 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B14 mock treatment 1739505.0 -91600.0 -0.17 1279248.0 -416000.0 -0.83 -0.7088 -0.8358 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B15 compound treatment 1870310.0 39200.0 0.07 1313569.0 -381000.0 -0.76 -0.4866 -0.6358 3631960 CBKinase1_022035 CCOc1ccc(cc1)n2nc3cc(C)c(NC(=O)c4cc(ccc4Cl)n5cnnc5)cc3n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B16 compound treatment 1856521.0 25400.0 0.05 956742.0 -738000.0 -1.48 -1.0092 -0.6839 3631961 CBKinase1_022036 Cc1cc(nc(SCC(=O)Nc2ccccc2)n1)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B17 compound treatment 2053039.0 222000.0 0.42 1668389.0 -26400.0 -0.05 0.2574 0.6128 3631962 CBKinase1_022037 OC(=O)C1CCCCC1C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B18 compound treatment 2048588.0 218000.0 0.41 1457194.0 -238000.0 -0.47 -0.047 -0.075 3631963 CBKinase1_022038 Cn1c(SCC(=O)Nc2ccc(Br)c(Cl)c2)nnc1c3ccccc3F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B19 compound treatment 1417169.0 -414000.0 -0.78 1201401.0 -493000.0 -0.99 -1.2467 -0.993 3631964 CBKinase1_022039 CCOC(=O)c1sc(NC(=O)CSc2nc(c3CCCCc3n2)C(F)(F)F)c(C#N)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B20 compound treatment 1843909.0 12800.0 0.02 1332760.0 -362000.0 -0.72 -0.4946 -0.6832 3631965 CBKinase1_022040 Cc1c(Cl)cccc1NC(=O)CSc2nc3sc4CCCCc4c3c(=O)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B21 compound treatment 1881322.0 50200.0 0.09 1269799.0 -425000.0 -0.85 -0.5339 -0.6247 3631966 CBKinase1_022041 CCOc1cc(ccc1Cl)S(=O)(=O)NCc2ccco2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B22 compound treatment 1517610.0 -313000.0 -0.59 1188009.0 -507000.0 -1.01 -1.1323 -0.9666 3631967 CBKinase1_022042 Oc1ccc(cc1)N2CC(CC2=O)C(=O)NCc3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B23 compound treatment 1497382.0 -334000.0 -0.63 1212520.0 -482000.0 -0.96 -1.1245 -0.9782 3631968 CBKinase1_022043 CN(c1cccc(NC(=O)c2ccc(Cl)c(c2)S(=O)(=O)Nc3ccccc3)c1)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 B24 compound treatment 1140847.0 -690000.0 -1.3 978016.0 -717000.0 -1.43 -1.9292 -0.9987 3631969 CBKinase1_022044 Cc1csc2nc(SCC(=O)Nc3ccc(cc3)[N+](=O)[O-])[nH]c(=O)c12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C01 compound treatment 1435282.0 -396000.0 -0.74 1440387.0 -254000.0 -0.51 -0.8849 -0.9829 3631970 CBKinase1_022045 CC(C)Nc1nc(SCC(=O)N)nc(n1)N2CCOCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C02 compound treatment 1800646.0 -30400.0 -0.06 988507.0 -706000.0 -1.41 -1.0385 -0.7351 3631971 CBKinase1_022046 COc1ccc(OC)c(NC(=O)Cn2cc(C(=O)c3ccccc3)c4ccccc24)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C03 compound treatment 1455613.0 -375000.0 -0.7 1274235.0 -421000.0 -0.84 -1.0927 -0.9962 3631972 CBKinase1_022047 CC1(C)Cc2c(CO1)sc3c2c4ncnn4c5nnc(SCC(=O)NCc6ccccc6)n53 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C04 compound treatment 1840209.0 9130.0 0.02 1364750.0 -330000.0 -0.66 -0.4543 -0.6885 3631973 CBKinase1_022048 COC(=O)c1ccccc1NC(=O)CSc2nc(c3CCCCc3n2)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C05 compound treatment 1669998.0 -161000.0 -0.3 1673335.0 -21400.0 -0.04 -0.2441 -0.7992 3631974 CBKinase1_022049 OCCCNc1ncnc2scc(c3ccc(Br)cc3)c12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C06 compound treatment 1729033.0 -102000.0 -0.19 1824351.0 130000.0 0.26 0.0477 0.148 3631975 CBKinase1_022050 FC(F)(F)c1nc(SCC(=O)N2c3ccccc3Sc4ccccc24)nc5CCCCc15 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C07 compound treatment 1665732.0 -165000.0 -0.31 1261940.0 -433000.0 -0.87 -0.8312 -0.9044 1249649 CBKinase1_022051 O=C(COc1ccc2oc3CCCCc3c2c1)NCCN4CCOCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C08 compound treatment 1800081.0 -31000.0 -0.06 1389542.0 -305000.0 -0.61 -0.4725 -0.7711 3631976 CBKinase1_022052 Cc1c(oc2cc(C)ccc12)C(=O)Nc3ccc(cc3)S(=O)(=O)Nc4ncccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C09 compound treatment 2093922.0 263000.0 0.49 1719417.0 24700.0 0.05 0.3838 0.7739 3631977 CBKinase1_022053 OC(=O)CCNC(=O)c1ccc(C#CC2(O)CCCCC2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C10 compound treatment 2099297.0 268000.0 0.5 1463841.0 -231000.0 -0.46 0.0297 0.0435 3631978 CBKinase1_022054 Cc1n[nH]c(C)c1SCC(=O)Nc2ccc(F)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C11 mock treatment 1786952.0 -44100.0 -0.08 1675271.0 -19500.0 -0.04 -0.0861 -0.9407 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C12 mock treatment 1595620.0 -235000.0 -0.44 1634671.0 -60100.0 -0.12 -0.3975 -0.8678 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C13 compound treatment 1671152.0 -160000.0 -0.3 1358448.0 -336000.0 -0.67 -0.6876 -0.934 3631979 CBKinase1_022055 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2ccccc2C(=O)NC3CCCCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C14 compound treatment 1895824.0 64700.0 0.12 1476887.0 -218000.0 -0.44 -0.222 -0.491 3631980 CBKinase1_022056 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3cccc(c3)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C15 mock treatment 1727756.0 -103000.0 -0.19 1065877.0 -629000.0 -1.26 -1.0259 -0.8067 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C16 mock treatment 1333371.0 -498000.0 -0.93 1693322.0 -1430.0 0.0 -0.6627 -0.7093 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C17 compound treatment 1375343.0 -456000.0 -0.86 897513.0 -797000.0 -1.59 -1.7317 -0.9575 3631981 CBKinase1_022057 CN(CC(=O)Nc1ccccc1C#N)S(=O)(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C18 compound treatment 1411580.0 -419000.0 -0.79 1579397.0 -115000.0 -0.23 -0.7199 -0.8773 3631982 CBKinase1_022058 O=C(Cn1cnc2sc(cc2c1=O)c3ccccc3)NCc4ccco4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C19 compound treatment 1336197.0 -495000.0 -0.93 1396997.0 -298000.0 -0.6 -1.0778 -0.9768 3631983 CBKinase1_022059 CCn1c2ccccc2c3cc(NC(=O)CN(C)S(=O)(=O)c4ccccc4)ccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C20 compound treatment 1781017.0 -50100.0 -0.09 1787509.0 92800.0 0.19 0.0646 0.311 3631984 CBKinase1_022060 COc1cc(NC(=O)CS(=O)(=O)c2ccc(C)cc2)cc(OC)c1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C21 compound treatment 1677596.0 -153000.0 -0.29 908412.0 -786000.0 -1.57 -1.3151 -0.823 3631985 CBKinase1_022061 CN(CC(=O)Nc1ccc(cc1)C(=O)C)S(=O)(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C22 compound treatment 1470461.0 -361000.0 -0.68 1272548.0 -422000.0 -0.84 -1.0754 -0.994 3631986 CBKinase1_022062 COc1ccc(cc1)N(Cc2cc3cccc(C)c3nc2O)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C23 compound treatment 1208461.0 -623000.0 -1.17 1331119.0 -364000.0 -0.73 -1.3404 -0.9739 3631987 CBKinase1_022063 CN(Cc1nc(no1)c2ccncc2)S(=O)(=O)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 C24 compound treatment 1412280.0 -419000.0 -0.79 1135167.0 -560000.0 -1.12 -1.3468 -0.9851 3631988 CBKinase1_022064 Clc1ccccc1c2nnc(SCC(=O)N3CCc4ccccc34)n2c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D01 compound treatment 425558.0 -1410000.0 -2.64 427619.0 -1270000.0 -2.53 -3.6566 -0.9998 3631989 CBKinase1_022065 COc1ccc(Br)cc1C(Nc2ccccn2)c3cc(Cl)c4cccnc4c3O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D02 compound treatment 1835253.0 4180.0 0.01 1393456.0 -301000.0 -0.6 -0.4203 -0.6978 3631990 CBKinase1_022066 COc1ccc(NC(=O)c2ccc(cc2)N(C)S(=O)(=O)c3ccc(OC)c(OC)c3)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D03 compound treatment 1958993.0 128000.0 0.24 1568053.0 -127000.0 -0.25 -0.0093 -0.0265 3631991 CBKinase1_022067 CCn1c(SCC(=O)Nc2cccc(Br)c2)nnc1c3ccc(C)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D04 compound treatment 1676783.0 -154000.0 -0.29 1610975.0 -83800.0 -0.17 -0.3232 -0.9661 3631992 CBKinase1_022068 CC(Oc1ccc(cc1)C(=O)Nc2ccc(Cl)cc2)C(=O)Nc3cc(Cl)ccc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D05 compound treatment 1879019.0 47900.0 0.09 1650423.0 -44300.0 -0.09 0.001 0.0078 3631993 CBKinase1_022069 COc1cc(cc(Br)c1O)C(Nc2ccccn2)c3cc(Cl)c4cccnc4c3O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D06 compound treatment 2052809.0 222000.0 0.42 1569673.0 -125000.0 -0.25 0.1176 0.2421 3631994 CBKinase1_022070 COc1ccc(cc1)c2cc(C)nc(SCC(=O)c3cccc(c3)[N+](=O)[O-])n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D07 compound treatment 1841203.0 10100.0 0.02 1755557.0 60800.0 0.12 0.0994 0.8079 3631995 CBKinase1_022071 Fc1cccc(NC(=O)CSc2nnc([nH]2)c3ccc(Cl)cc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D08 compound treatment 1776792.0 -54300.0 -0.1 1741286.0 46500.0 0.09 -0.0063 -0.0457 3631996 CBKinase1_022072 CCOC(=O)c1c(NC(=O)C(C)Oc2ccc3c(C)cc(=O)oc3c2)sc4CCCCc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D09 compound treatment 1650550.0 -181000.0 -0.34 2026246.0 331000.0 0.66 0.2288 0.3075 3631997 CBKinase1_022073 Oc1cc(ccc1NC(=O)COc2ccccc2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D10 compound treatment 1798898.0 -32200.0 -0.06 1527074.0 -168000.0 -0.34 -0.2797 -0.8213 3631998 CBKinase1_022074 OC1(CC(=O)c2cccnc2)C(=O)N(Cc3ccccc3)c4ccc(Br)cc41 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D11 mock treatment 1945593.0 115000.0 0.21 1384178.0 -311000.0 -0.62 -0.2869 -0.4368 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D12 mock treatment 1878757.0 47700.0 0.09 1578379.0 -116000.0 -0.23 -0.1012 -0.406 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D13 compound treatment 2049833.0 219000.0 0.41 1697384.0 2630.0 0.01 0.2941 0.7161 3631999 CBKinase1_022075 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D14 compound treatment 1902116.0 71000.0 0.13 1458208.0 -237000.0 -0.47 -0.24 -0.4886 3632000 CBKinase1_022076 CCn1c(SCC(=O)Nc2cccc(F)c2)nnc1c3ccc(C)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D15 mock treatment 2086420.0 255000.0 0.48 1481305.0 -213000.0 -0.43 0.0373 0.0581 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D16 mock treatment 1761143.0 -69900.0 -0.13 1735450.0 40700.0 0.08 -0.0353 -0.2287 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D17 compound treatment 1720136.0 -111000.0 -0.21 1459848.0 -235000.0 -0.47 -0.4793 -0.9331 3632001 CBKinase1_022077 CC(Oc1ccc(cc1)C(=O)NC2CCCCC2)C(=O)Nc3ccccc3C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D18 compound treatment 1495826.0 -335000.0 -0.63 1737597.0 42800.0 0.09 -0.3845 -0.6053 3632002 CBKinase1_022078 O=C(CSc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1Cc5ccco5)c6cccs6 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D19 compound treatment 1631852.0 -199000.0 -0.37 1822564.0 128000.0 0.26 -0.0838 -0.1851 3632003 CBKinase1_022079 CCS(=O)(=O)c1nc2ccccc2n1CC(=O)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D20 compound treatment 1474572.0 -357000.0 -0.67 1699128.0 4380.0 0.01 -0.4671 -0.6978 3632004 CBKinase1_022080 Cc1ccc(NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D21 compound treatment 1680873.0 -150000.0 -0.28 1347591.0 -347000.0 -0.69 -0.69 -0.9213 3632005 CBKinase1_022081 O=C(CN1C(=O)c2ccccc2C1=O)Oc3c(oc4ccccc4c3=O)c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D22 compound treatment 1544613.0 -286000.0 -0.54 1273273.0 -421000.0 -0.84 -0.9759 -0.9765 3117986 CBKinase1_022082 COC(=O)c1ccccc1NC(=O)C(C)N2c3cccc4cccc(c34)S2(=O)=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D23 compound treatment 1463630.0 -367000.0 -0.69 1101135.0 -594000.0 -1.19 -1.3267 -0.9667 3632006 CBKinase1_022083 CCN(CC)CCSc1nnc2c3cc(C)ccc3n(C)c2n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 D24 compound treatment 1148868.0 -682000.0 -1.28 1159530.0 -535000.0 -1.07 -1.662 -0.996 3632007 CBKinase1_022084 [O-][N+](=O)c1cccc(NC(=O)C2CCCN(C2)S(=O)(=O)c3ccc(F)cc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E01 mock treatment 1594335.0 -237000.0 -0.44 1616732.0 -78000.0 -0.16 -0.4245 -0.9013 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E02 mock treatment 1832361.0 1280.0 0.0 1460825.0 -234000.0 -0.47 -0.3289 -0.7035 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E03 compound treatment 2131942.0 301000.0 0.56 1583903.0 -111000.0 -0.22 0.2427 0.4001 3632008 CBKinase1_022085 CC(=O)c1ccc(NC(=O)CN(c2ccc(I)cc2)S(=O)(=O)C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E04 compound treatment 2075811.0 245000.0 0.46 1542810.0 -152000.0 -0.3 0.1101 0.2 3632009 CBKinase1_022086 Cc1nc(SCC(=O)Nc2cccc(Cl)c2Cl)nc3CCCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E05 compound treatment 1933132.0 102000.0 0.19 1470973.0 -224000.0 -0.45 -0.1808 -0.3716 3632010 CBKinase1_022087 OC(=O)C(Sc1cccc2cccc(C(=O)O)c12)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E06 compound treatment 1744891.0 -86200.0 -0.16 1689208.0 -5540.0 -0.01 -0.1222 -0.7538 3632011 CBKinase1_022088 COC(=O)c1ccc(NC(=O)C(C)N(c2ccc(C)c(C)c2)S(=O)(=O)C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E07 compound treatment 1763419.0 -67700.0 -0.13 1644414.0 -50300.0 -0.1 -0.161 -0.9933 3632012 CBKinase1_022089 COC(=O)c1ccc(C(=O)OC)c(NC(=O)COc2ccc3oc4CCCCc4c3c2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E08 compound treatment 1964426.0 133000.0 0.25 1941081.0 246000.0 0.49 0.5251 0.9508 3632013 CBKinase1_022090 Cc1c(oc2cc(C)ccc12)C(=O)Nc3sc4CCCCc4c3C(=O)NCC5CCCO5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E09 mock treatment 2202021.0 371000.0 0.7 1664287.0 -30500.0 -0.06 0.4494 0.6428 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E10 mock treatment 1905774.0 74700.0 0.14 1738302.0 43500.0 0.09 0.1607 0.9737 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E11 compound treatment 1548648.0 -282000.0 -0.53 1757848.0 63100.0 0.13 -0.2857 -0.5243 1511683 CBKinase1_022091 Cn1c(=O)n(C)c2ncn(CCCN)c2c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E12 compound treatment 2089442.0 258000.0 0.49 2045280.0 351000.0 0.7 0.8384 0.9839 3632014 CBKinase1_022092 Cc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccccc3)cc1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E13 compound treatment 2094057.0 263000.0 0.49 2339358.0 645000.0 1.29 1.2601 0.9133 3632015 CBKinase1_022093 Cc1cc(OCC(=O)Nc2ccccc2C(=O)NC3CCCCC3)ccc1Br 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E14 compound treatment 2017606.0 187000.0 0.35 1733984.0 39200.0 0.08 0.3031 0.8445 3632016 CBKinase1_022094 COc1cc(ccc1Br)S(=O)(=O)NCc2ccccn2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E15 compound treatment 1858852.0 27800.0 0.05 1478953.0 -216000.0 -0.43 -0.2681 -0.6171 3632017 CBKinase1_022095 COc1ccc(NC(=O)CCCN2C(=O)CCC2=O)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E16 compound treatment 2401829.0 571000.0 1.07 1711516.0 16800.0 0.03 0.7814 0.7289 3211380 CBKinase1_022096 COc1cccc(NC(=O)Cn2c(nc3ccccc23)c4cncs4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E17 mock treatment 2311462.0 480000.0 0.9 1631042.0 -63700.0 -0.13 0.5477 0.6013 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E18 mock treatment 1702620.0 -128000.0 -0.24 1816037.0 121000.0 0.24 9.0E-4 0.0026 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E19 compound treatment 1592719.0 -238000.0 -0.45 1526428.0 -168000.0 -0.34 -0.5543 -0.9901 3632018 CBKinase1_022097 COc1cc2c(cc1NC(=O)CN(C)S(=O)(=O)c3ccccc3)oc4ccccc42 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E20 compound treatment 1245409.0 -586000.0 -1.1 1261239.0 -434000.0 -0.87 -1.3901 -0.993 3632019 CBKinase1_022098 COc1ccc(OC)c(c1)S(=O)(=O)N(C)CC(=O)Nc2cccc(Cl)c2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E21 compound treatment 1450928.0 -380000.0 -0.71 1307922.0 -387000.0 -0.77 -1.0513 -0.9992 3632020 CBKinase1_022099 COc1cc(OC)c(NC(=O)CN(C)S(=O)(=O)c2ccccc2)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E22 compound treatment 1602440.0 -229000.0 -0.43 1367834.0 -327000.0 -0.65 -0.7655 -0.9792 3632021 CBKinase1_022100 Cc1ccccc1c2nnc(SCC(=O)Nc3sc4CCCCc4c3C#N)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E23 compound treatment 1329804.0 -501000.0 -0.94 1335591.0 -359000.0 -0.72 -1.173 -0.9911 3632022 CBKinase1_022101 CN(Cc1nc(no1)c2ccccn2)S(=O)(=O)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 E24 compound treatment 1424297.0 -407000.0 -0.76 1231246.0 -464000.0 -0.93 -1.1951 -0.9954 3632023 CBKinase1_022102 COc1ccc(cc1Cl)S(=O)(=O)NCCc2ccc(OC)c(OC)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F01 mock treatment 1336403.0 -495000.0 -0.93 1441837.0 -253000.0 -0.51 -1.0141 -0.9591 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F02 mock treatment 1997493.0 166000.0 0.31 1667874.0 -26900.0 -0.05 0.1829 0.577 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F03 compound treatment 2180840.0 350000.0 0.66 1505269.0 -189000.0 -0.38 0.1965 0.2592 3632024 CBKinase1_022103 COc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(F)c3)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F04 compound treatment 2010266.0 179000.0 0.34 1676081.0 -18700.0 -0.04 0.2115 0.6248 3632025 CBKinase1_022104 Cc1sc2ncn(CC(=O)Nc3ccccc3C(F)(F)F)c(=O)c2c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F05 compound treatment 2132595.0 302000.0 0.57 1600460.0 -94300.0 -0.19 0.267 0.4475 3632026 CBKinase1_022105 NC(=O)CN(c1cc(Cl)ccc1Cl)S(=O)(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F06 compound treatment 1955267.0 124000.0 0.23 1968861.0 274000.0 0.55 0.5523 0.9275 3632027 CBKinase1_022106 COc1ccc(CNc2nc3[nH]c(C)cc(=O)n3n2)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F07 compound treatment 360235.0 -1470000.0 -2.76 369982.0 -1320000.0 -2.65 -3.8248 -0.9998 3632028 CBKinase1_022107 Oc1c(cc(Cl)c2cccnc12)C(Nc3ccccn3)c4cccc(F)c4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F08 compound treatment 2349606.0 519000.0 0.97 1946645.0 252000.0 0.5 1.0443 0.9529 3632029 CBKinase1_022108 COc1ccc(cc1Cl)S(=O)(=O)N(CC(=O)N)C2CCCCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F09 mock treatment 2405328.0 574000.0 1.08 2157744.0 463000.0 0.93 1.4166 0.9971 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F10 mock treatment 2271968.0 441000.0 0.83 1895667.0 201000.0 0.4 0.8692 0.9448 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F11 compound treatment 2479066.0 648000.0 1.22 2014518.0 320000.0 0.64 1.3121 0.9548 3632030 CBKinase1_022109 Cc1cc(OCC(=O)Nc2ccccc2C(=O)O)cc(C)c1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F12 compound treatment 2642964.0 812000.0 1.52 2004612.0 310000.0 0.62 1.5157 0.9213 3632031 CBKinase1_022110 CCn1c(SCC(=O)Nc2ccc(F)c(F)c2F)nnc1c3ccccc3O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F13 compound treatment 2406051.0 575000.0 1.08 1945862.0 251000.0 0.5 1.1182 0.9393 3632032 CBKinase1_022111 CCN(CC(=O)Nc1ccc(I)cc1)S(=O)(=O)c2ccc(C)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F14 compound treatment 1849386.0 18300.0 0.03 1519160.0 -176000.0 -0.35 -0.2239 -0.6348 3632033 CBKinase1_022112 N#Cc1ccccc1OCCCn2cnc3ccccc23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F15 compound treatment 2179186.0 348000.0 0.65 2024082.0 329000.0 0.66 0.9275 1.0 3632034 CBKinase1_022113 COc1ccc(OC)c(c1)S(=O)(=O)N(C)CC(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F16 compound treatment 2132080.0 301000.0 0.57 1590590.0 -104000.0 -0.21 0.2524 0.4191 3632035 CBKinase1_022114 Cc1[nH]c2ccccc2c1C(=O)CSc3nc4scc(c5ccco5)c4c(=O)n3c6ccccc6 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F17 mock treatment 2299633.0 469000.0 0.88 1736080.0 41300.0 0.08 0.6804 0.7701 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F18 mock treatment 2196720.0 366000.0 0.69 1894937.0 200000.0 0.4 0.7683 0.967 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F19 compound treatment 1967368.0 136000.0 0.26 1426551.0 -268000.0 -0.54 -0.1981 -0.3335 3123755 CBKinase1_022115 CCc1ccccc1NC(=O)CSc2nc3cccnc3[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F20 compound treatment 1951874.0 121000.0 0.23 1506896.0 -188000.0 -0.38 -0.1051 -0.2397 3632036 CBKinase1_022116 CCc1c(C#N)c(SCC(=O)c2c(C)[nH]c3ccccc23)nc4CC(C)(C)CC(=O)c14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F21 compound treatment 1997441.0 166000.0 0.31 1919383.0 225000.0 0.45 0.5383 0.9843 3632037 CBKinase1_022117 CCc1nnc(SCC(=O)Nc2c(C)cc(C)cc2[N+](=O)[O-])[nH]1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F22 compound treatment 2000124.0 169000.0 0.32 1487621.0 -207000.0 -0.41 -0.0683 -0.131 3632038 CBKinase1_022118 O=C(CS(=O)(=O)c1ccccc1)Nc2ccc3OCCOc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F23 compound treatment 1771407.0 -59700.0 -0.11 1360061.0 -335000.0 -0.67 -0.5522 -0.8142 3632039 CBKinase1_022119 COc1ccc(OC)c(NC(=O)COc2ccc3c4CCCc4c(=O)oc3c2C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 F24 compound treatment 1502482.0 -329000.0 -0.62 1305180.0 -390000.0 -0.78 -0.9868 -0.9934 3632040 CBKinase1_022120 CCCc1cc(=O)n2nc(NCc3ccccc3OC)nc2[nH]1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G01 compound treatment 1630936.0 -200000.0 -0.38 1284385.0 -410000.0 -0.82 -0.8457 -0.9374 3632041 CBKinase1_022121 COc1ccccc1NC(=O)CSc2nc(nc3CC(C)(C)OCc23)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G02 compound treatment 2035606.0 205000.0 0.38 1840570.0 146000.0 0.29 0.4776 0.9907 3632042 CBKinase1_022122 COc1ccc(OC)c(NC(=O)Cn2cc(C(=O)c3cccs3)c4ccccc24)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G03 mock treatment 2123239.0 292000.0 0.55 1904648.0 210000.0 0.42 0.6845 0.9912 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G04 mock treatment 1816777.0 -14300.0 -0.03 1874961.0 180000.0 0.36 0.2357 0.6526 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G05 compound treatment 2097768.0 267000.0 0.5 2094270.0 400000.0 0.8 0.9187 0.9747 1723892 CBKinase1_022123 Cc1cc(=O)oc2cc(OCC(=O)Nc3cccc(c3)C(=O)O)ccc12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G06 compound treatment 2119572.0 288000.0 0.54 2121370.0 427000.0 0.85 0.9859 0.976 3632043 CBKinase1_022124 COc1ccc(NC(=O)C2(CC3CC4C2)CC(C3)(C4)C(=O)Nc5ccc(OC)c(OC)c5)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G07 compound treatment 2308541.0 477000.0 0.9 2199175.0 504000.0 1.01 1.3467 0.9983 3632044 CBKinase1_022125 CCOC(=O)c1c(C)n(C)c2cccc(OC(=O)CN3C(=O)c4ccccc4C3=O)c12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G08 compound treatment 2379615.0 549000.0 1.03 2224149.0 529000.0 1.06 1.4764 0.9999 3632045 CBKinase1_022126 Cc1c(oc2cc(C)ccc12)C(=O)Nc3sc4CCCc4c3C(=O)NCC5CCCO5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G09 compound treatment 2417798.0 587000.0 1.1 2323482.0 629000.0 1.26 1.6674 0.9978 3632046 CBKinase1_022127 CC(C)(O)C#Cc1ccc(cc1)C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G10 compound treatment 2598359.0 767000.0 1.44 2440738.0 746000.0 1.49 2.0728 0.9999 3632047 CBKinase1_022128 COc1ccc(NC(=O)CSc2c(C)n[nH]c2C)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G11 compound treatment 2378262.0 547000.0 1.03 2252362.0 558000.0 1.11 1.5144 0.9992 3632048 CBKinase1_022129 Cn1c(=O)n(C)c2ncn(CCCNC3=CC(C)(C)CC(=O)C3)c2c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G12 compound treatment 2388477.0 557000.0 1.05 2247410.0 553000.0 1.1 1.521 0.9996 3632049 CBKinase1_022130 Clc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccccc3)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G13 compound treatment 2502237.0 671000.0 1.26 2276813.0 582000.0 1.16 1.7136 0.9992 3632050 CBKinase1_022131 OC(=O)C1CCCCC1C(=O)Nc2ccccc2C(=O)NC3CCCCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G14 compound treatment 2150417.0 319000.0 0.6 2222616.0 528000.0 1.06 1.1699 0.9641 3632051 CBKinase1_022132 COc1ccccc1NC(=O)C2CCCN(C2)S(=O)(=O)c3ccc(Br)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G15 compound treatment 2457435.0 626000.0 1.18 2242938.0 548000.0 1.1 1.6062 0.9994 3632052 CBKinase1_022133 CN(CC(=O)Nc1cccc2CCCCc12)S(=O)(=O)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G16 compound treatment 2258864.0 428000.0 0.8 2212843.0 518000.0 1.04 1.3001 0.9921 3632053 CBKinase1_022134 CCCc1cc(=O)n2nc(NCc3cccc(c3)[N+](=O)[O-])nc2[nH]1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G17 compound treatment 2258993.0 428000.0 0.8 2143292.0 449000.0 0.9 1.202 0.9985 3632054 CBKinase1_022135 CN(CC(=O)Nc1ccc(C#N)cc1)S(=O)(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G18 compound treatment 1922506.0 91400.0 0.17 1734014.0 39300.0 0.08 0.1769 0.9371 3632055 CBKinase1_022136 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)Nc2cccc(Br)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G19 mock treatment 2111030.0 280000.0 0.53 2166188.0 471000.0 0.94 1.0379 0.962 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G20 mock treatment 1938279.0 107000.0 0.2 1804540.0 110000.0 0.22 0.2975 0.9991 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G21 compound treatment 2016349.0 185000.0 0.35 1813610.0 119000.0 0.24 0.4139 0.9827 3632056 CBKinase1_022137 CN(CC(=O)Nc1ccc(Br)cc1C)S(=O)(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G22 compound treatment 2027141.0 196000.0 0.37 1782171.0 87400.0 0.17 0.3838 0.942 3632057 CBKinase1_022138 COC(=O)c1ccccc1NC(=O)CNC(=O)c2ccccc2F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G23 compound treatment 1830136.0 -942.0 0.0 1857188.0 162000.0 0.32 0.2283 0.7032 3632058 CBKinase1_022139 NC(=O)CSc1nc2ccc(I)cc2c(=O)n1Cc3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 G24 compound treatment 2006754.0 176000.0 0.33 1646388.0 -48400.0 -0.1 0.1649 0.4797 3632059 CBKinase1_022140 O=C(CN1CCN(Cc2ccccc2)CC1)Nc3sc4CCCCc4c3C#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H01 compound treatment 1462569.0 -369000.0 -0.69 1720686.0 25900.0 0.05 -0.4525 -0.6523 3632060 CBKinase1_022141 Cn1c(SCC(=O)c2ccccc2)nnc1c3cc4ccccc4o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H02 compound treatment 2172248.0 341000.0 0.64 1693659.0 -1090.0 0.0 0.4514 0.7047 3632061 CBKinase1_022142 COc1ccc(cc1)c2cc(C)nc(SCc3cccc(c3)C(=O)O)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H03 mock treatment 2118374.0 287000.0 0.54 1909290.0 215000.0 0.43 0.6846 0.9935 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H04 mock treatment 2388639.0 558000.0 1.05 2056617.0 362000.0 0.72 1.2516 0.9837 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H05 compound treatment 2110143.0 279000.0 0.52 1890189.0 195000.0 0.39 0.6467 0.9895 3632062 CBKinase1_022143 Brc1cccc(NC(=O)CSc2nnc(o2)c3ccccc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H06 compound treatment 2159171.0 328000.0 0.62 1975569.0 281000.0 0.56 0.8324 0.9989 3632063 CBKinase1_022144 COc1ccc(NC(=O)c2ccc(OC(C)C(=O)Nc3ccccc3C(F)(F)F)cc2)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H07 compound treatment 2407933.0 577000.0 1.08 2229135.0 534000.0 1.07 1.521 1.0 3632064 CBKinase1_022145 Cn1c(SCC(=O)Nc2cccc(Br)c2)nnc1c3cc4ccccc4o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H08 compound treatment 2435473.0 604000.0 1.13 2102144.0 407000.0 0.81 1.3781 0.9868 3632065 CBKinase1_022146 COc1ccc(cc1)c2cc(nc(SCC(=O)Nc3ccc(C)cc3)n2)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H09 compound treatment 2473723.0 643000.0 1.21 2308865.0 614000.0 1.23 1.721 1.0 3632066 CBKinase1_022147 CCn1c(SCC(=O)Nc2cccc(Br)c2)nnc1c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H10 compound treatment 2553048.0 722000.0 1.36 2126816.0 432000.0 0.86 1.569 0.9763 3632067 CBKinase1_022148 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2cc(ccc2Cl)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H11 compound treatment 2710290.0 879000.0 1.65 2384486.0 690000.0 1.38 2.1419 0.996 3632068 CBKinase1_022149 O=C(Nc1ccccc1)c2ccc(cc2)S(=O)(=O)NCc3ccncc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H12 compound treatment 2725115.0 894000.0 1.68 2337882.0 643000.0 1.29 2.0957 0.9913 3632069 CBKinase1_022150 CCN(CC(=O)Nc1ccc2OCCOc2c1)S(=O)(=O)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H13 compound treatment 2797191.0 966000.0 1.81 2234451.0 540000.0 1.08 2.0452 0.9692 3632070 CBKinase1_022151 Cc1cccc(NC(=O)C2CC(=O)n3c(N2)nc4ccccc34)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H14 compound treatment 307569.0 -1520000.0 -2.86 284779.0 -1410000.0 -2.82 -4.0151 -1.0 3632071 CBKinase1_022152 CCc1ccc(cc1)C(Nc2ccccn2)c3cc(Cl)c4cccnc4c3O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H15 compound treatment 2514398.0 683000.0 1.28 2222875.0 528000.0 1.06 1.6535 0.9953 3632072 CBKinase1_022153 Cc1cc(C)c(C)c(Oc2coc3cc(OC(=O)CCN4C(=O)c5ccccc5C4=O)ccc3c2=O)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H16 compound treatment 2372568.0 541000.0 1.02 1999963.0 305000.0 0.61 1.1502 0.9702 3632073 CBKinase1_022154 COc1ccccc1NC(=O)COc2ccc(Cl)cc2CO 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H17 compound treatment 2405312.0 574000.0 1.08 2185325.0 491000.0 0.98 1.4556 0.9989 3632074 CBKinase1_022155 Cc1cc(ccc1Br)N(CC(=O)Nc2cccc([N+](=O)[O-])c2C)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H18 compound treatment 2093311.0 262000.0 0.49 2070365.0 376000.0 0.75 0.879 0.9791 3632075 CBKinase1_022156 CC(C)NS(=O)(=O)c1ccc(OCC(=O)N2CCOCC2)c(Cl)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H19 mock treatment 2167959.0 337000.0 0.63 1865245.0 170000.0 0.34 0.6882 0.9579 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H20 mock treatment 2083313.0 252000.0 0.47 1892334.0 198000.0 0.39 0.6141 0.9959 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H21 compound treatment 2115589.0 285000.0 0.53 1892487.0 198000.0 0.4 0.6571 0.989 3632076 CBKinase1_022157 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2ccccc2OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H22 compound treatment 2108230.0 277000.0 0.52 1707703.0 13000.0 0.03 0.3862 0.7414 3632077 CBKinase1_022158 Cc1ccc(cc1C)n2nnnc2SCC(=O)Nc3ccc(N4CCOCC4)c(Cl)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H23 compound treatment 2027502.0 196000.0 0.37 1625573.0 -69200.0 -0.14 0.163 0.4138 3632078 CBKinase1_022159 [O-][N+](=O)c1ccccc1NC(=O)NCCCN2CCCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 H24 compound treatment 1205100.0 -626000.0 -1.18 1527189.0 -168000.0 -0.33 -1.0678 -0.8738 3632079 CBKinase1_022160 COc1ccccc1NC(=O)CSc2nc(nc3CC(C)(C)OCc23)c4ccc(C)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I01 compound treatment 1527706.0 -303000.0 -0.57 1303357.0 -391000.0 -0.78 -0.9559 -0.9878 3632080 CBKinase1_022161 CC(Sc1nc(nc2CC(C)(C)OCc12)c3ccc(C)cc3)C(=O)Nc4ccc(C)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I02 compound treatment 1984069.0 153000.0 0.29 1440027.0 -255000.0 -0.51 -0.1569 -0.2684 3632081 CBKinase1_022162 COc1ccc(cc1N(CC(=O)Nc2cc(Cl)ccc2Cl)S(=O)(=O)C)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I03 compound treatment 1917043.0 86000.0 0.16 1699171.0 4420.0 0.01 0.1204 0.7447 3632082 CBKinase1_022163 COC(=O)CN(c1ccc2OCCOc2c1)S(=O)(=O)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I04 compound treatment 2239970.0 409000.0 0.77 1806485.0 112000.0 0.22 0.7007 0.8765 3632083 CBKinase1_022164 Cc1cccc(C)c1OCC(=O)NCc2cccnc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I05 mock treatment 2251232.0 420000.0 0.79 1971439.0 277000.0 0.55 0.9488 0.9849 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I06 mock treatment 2345063.0 514000.0 0.96 1827280.0 133000.0 0.26 0.8696 0.8691 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I07 compound treatment 2219363.0 388000.0 0.73 2025054.0 330000.0 0.66 0.9823 0.9988 3632084 CBKinase1_022165 CCOC(=O)c1c(C)c(C)sc1NC(=O)c2c(NC(=O)C)sc3CCCCc23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I08 compound treatment 2284633.0 454000.0 0.85 2155724.0 461000.0 0.92 1.2536 0.9992 3632085 CBKinase1_022166 Cc1c(oc2cc(C)ccc12)C(=O)Nc3sc4CCCc4c3C(=O)NCc5ccco5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I09 compound treatment 2189763.0 359000.0 0.67 2038940.0 344000.0 0.69 0.9626 0.9999 3632086 CBKinase1_022167 CC(Cc1c[nH]c2ccccc12)NC(=O)CN 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I10 compound treatment 2470110.0 639000.0 1.2 1998094.0 303000.0 0.61 1.277 0.95 3632087 CBKinase1_022168 CCc1ccccc1NC(=O)CSc2c(C)n[nH]c2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I11 compound treatment 2361817.0 531000.0 1.0 1996101.0 301000.0 0.6 1.1304 0.9709 3632088 CBKinase1_022169 CCOC(=O)c1sc2ncnc(NC(C)(C)C)c2c1CNC(C)(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I12 compound treatment 2685788.0 855000.0 1.6 2233085.0 538000.0 1.08 1.8954 0.9811 3632089 CBKinase1_022170 Cc1c(Cl)cccc1NC(=O)CSC2CC(=O)N(C2=O)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I13 compound treatment 2479423.0 648000.0 1.22 2086213.0 391000.0 0.78 1.4139 0.9772 3632090 CBKinase1_022171 COc1ccc(NC(=O)CCCN2C(=O)CCC2=O)c(OC)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I14 compound treatment 1958802.0 128000.0 0.24 1968299.0 274000.0 0.55 0.5561 0.9316 3632091 CBKinase1_022172 CC(Oc1ccc2c(C)cc(=O)oc2c1)C(=O)Nc3ccc(Cl)c(c3)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I15 compound treatment 2375894.0 545000.0 1.02 1705336.0 10600.0 0.02 0.7382 0.7216 3632092 CBKinase1_022173 COc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccccc2)c(c1)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I16 compound treatment 2465610.0 635000.0 1.19 1904435.0 210000.0 0.42 1.1387 0.9017 3632093 CBKinase1_022174 CC1CCc2c(C1)sc3ncn(CC(=O)Nc4sc5CCCc5c4C#N)c(=O)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I17 compound treatment 2034144.0 203000.0 0.38 2004053.0 309000.0 0.62 0.7067 0.973 3632094 CBKinase1_022175 CN(CC(=O)Nc1ccccc1C(=O)N)S(=O)(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I18 compound treatment 2356673.0 526000.0 0.99 2020918.0 326000.0 0.65 1.1587 0.9798 3632095 CBKinase1_022176 Nc1cc(O)nc(SCc2ccccc2C#N)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I19 compound treatment 1909279.0 78200.0 0.15 1619041.0 -75700.0 -0.15 -0.0032 -0.0151 3632096 CBKinase1_022177 CN(CC(=O)Nc1ccc(C)cc1[N+](=O)[O-])S(=O)(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I20 compound treatment 1534948.0 -296000.0 -0.56 1391383.0 -303000.0 -0.61 -0.8219 -0.9991 3632097 CBKinase1_022178 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2cccc(c2)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I21 mock treatment 2244543.0 413000.0 0.78 1890496.0 196000.0 0.39 0.8255 0.9497 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I22 mock treatment 2067278.0 236000.0 0.44 1811501.0 117000.0 0.23 0.4785 0.955 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I23 compound treatment 1611472.0 -220000.0 -0.41 1504729.0 -190000.0 -0.38 -0.5601 -0.9992 3632098 CBKinase1_022179 NC(=O)CSc1nnc(c2cc3ccccc3o2)n1c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 I24 compound treatment 1152459.0 -679000.0 -1.27 1238894.0 -456000.0 -0.91 -1.5451 -0.9865 1156449 CBKinase1_022180 C(Sc1nnc(c2ccccc2)n1c3ccccc3)c4nc5ccccc5s4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J01 compound treatment 1412813.0 -418000.0 -0.79 1345918.0 -349000.0 -0.7 -1.0482 -0.9982 3632099 CBKinase1_022181 CCn1c(SCC(=O)Nc2cccc(F)c2)nnc1c3ccc(Cl)cc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J02 compound treatment 1723377.0 -108000.0 -0.2 1469054.0 -226000.0 -0.45 -0.4619 -0.9345 3632100 CBKinase1_022182 CCOC(=O)c1c(C)c(C)sc1NC(=O)CSc2nncn2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J03 compound treatment 562033.0 -1270000.0 -2.38 569402.0 -1130000.0 -2.25 -3.2751 -0.9996 3632101 CBKinase1_022183 COc1ccc(cc1[N+](=O)[O-])C(Nc2ccccn2)c3cc(Cl)c4cccnc4c3O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J04 compound treatment 2049538.0 218000.0 0.41 1598683.0 -96100.0 -0.19 0.1542 0.3406 3632102 CBKinase1_022184 Fc1ccc(NC(=O)CSc2nc(c([nH]2)c3ccccc3)c4ccccc4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J05 mock treatment 1505877.0 -325000.0 -0.61 1709767.0 15000.0 0.03 -0.4105 -0.6715 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J06 mock treatment 1788142.0 -42900.0 -0.08 1632594.0 -62200.0 -0.12 -0.1448 -0.9781 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J07 compound treatment 2154679.0 324000.0 0.61 1766541.0 71800.0 0.14 0.531 0.8507 3632103 CBKinase1_022185 Cn1c(SCC(=O)Nc2cccc(F)c2)nnc1c3cc4ccccc4o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J08 compound treatment 2062942.0 232000.0 0.44 1520104.0 -175000.0 -0.35 0.061 0.1093 3632104 CBKinase1_022186 O=C(CCN1C(=O)c2ccccc2C1=O)Oc3c(oc4ccccc4c3=O)c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J09 compound treatment 1625799.0 -205000.0 -0.39 1808351.0 114000.0 0.23 -0.112 -0.2503 3632105 CBKinase1_022187 COc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(Br)c3)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J10 compound treatment 1845166.0 14100.0 0.03 1906879.0 212000.0 0.42 0.3185 0.7498 3632106 CBKinase1_022188 O=C(CSc1nc(nc(n1)N2CCCCC2)N3CCCCC3)N4CCc5ccccc45 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J11 compound treatment 2162499.0 331000.0 0.62 1821642.0 127000.0 0.25 0.6193 0.9217 3632107 CBKinase1_022189 Ic1ccc(OCC(=O)NCc2ccco2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J12 compound treatment 2273420.0 442000.0 0.83 1749218.0 54500.0 0.11 0.6642 0.793 3632108 CBKinase1_022190 COc1ccccc1C(=O)N(Cc2nc(no2)c3cccc(C)c3)C(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J13 compound treatment 2064158.0 233000.0 0.44 1792204.0 97500.0 0.19 0.4471 0.9335 3632109 CBKinase1_022191 Cc1nc(SCC(=O)Nc2cccc(c2)C(=O)O)nc(O)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J14 compound treatment 2332933.0 502000.0 0.94 2084677.0 390000.0 0.78 1.2173 0.9956 3632110 CBKinase1_022192 CNC(=O)CN(c1cccc(Cl)c1Cl)S(=O)(=O)c2ccc(C)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J15 compound treatment 1043976.0 -787000.0 -1.48 965861.0 -729000.0 -1.46 -2.075 -1.0 3632111 CBKinase1_022193 CCN(CC)CCSc1nnc2c3ccccc3n(CC)c2n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J16 compound treatment 2136353.0 305000.0 0.57 1859013.0 164000.0 0.33 0.6374 0.965 3632112 CBKinase1_022194 CS(=O)(=O)N(CC(=O)Nc1ccc2ccccc2c1)c3cc(Cl)c(Cl)cc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J17 compound treatment 1354733.0 -476000.0 -0.89 1382853.0 -312000.0 -0.62 -1.0731 -0.9844 3632113 CBKinase1_022195 Cc1c(n2c(/C=C\c3ccc(o3)[N+](=O)[O-])nc4ccccc4c2=O)c(=O)n(c5ccccc5)n1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J18 compound treatment 1976133.0 145000.0 0.27 1512195.0 -183000.0 -0.36 -0.0654 -0.1437 3632115 CBKinase1_022196 COc1ccc(NC(=O)C(C)N(c2ccc(C)cc2)S(=O)(=O)C)c(OC)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J19 compound treatment 1601075.0 -230000.0 -0.43 1848454.0 154000.0 0.31 -0.0881 -0.1663 3632116 CBKinase1_022197 CCN(CC(=O)Nc1ccc(Cl)cc1C)S(=O)(=O)c2ccc(C)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J20 compound treatment 2055386.0 224000.0 0.42 1703923.0 9170.0 0.02 0.3107 0.7372 3632117 CBKinase1_022198 CCc1c(C)nc(SCC(=O)Nc2ccc(C)cc2)nc1O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J21 mock treatment 2028705.0 198000.0 0.37 1580479.0 -114000.0 -0.23 0.1008 0.2315 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J22 mock treatment 1754114.0 -77000.0 -0.14 1557422.0 -137000.0 -0.27 -0.2963 -0.9551 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J23 compound treatment 1699323.0 -132000.0 -0.25 1503382.0 -191000.0 -0.38 -0.4454 -0.9777 3632118 CBKinase1_022199 CCN(CC(=O)Nc1ccc(I)cc1)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 J24 compound treatment 1121864.0 -709000.0 -1.33 1519812.0 -175000.0 -0.35 -1.1887 -0.8635 3632119 CBKinase1_022200 COc1ccc(Cl)cc1Nc2nc(N)nc(n2)c3oc4ccccc4c3C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K01 compound treatment 1620184.0 -211000.0 -0.4 1416829.0 -278000.0 -0.56 -0.6727 -0.9862 3632120 CBKinase1_022201 CCOC(=O)CSc1nnc2n3ncnc3c4c5CCC(C)Cc5sc4n12 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K02 compound treatment 1805901.0 -25200.0 -0.05 1650431.0 -44300.0 -0.09 -0.0961 -0.9567 3632121 CBKinase1_022202 Cc1ccccc1N(CC(=O)O)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K03 compound treatment 1786991.0 -44100.0 -0.08 1467194.0 -228000.0 -0.45 -0.3801 -0.8223 3632122 CBKinase1_022203 COC(=O)CN(c1cc(ccc1C)[N+](=O)[O-])S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K04 compound treatment 1785953.0 -45100.0 -0.08 1612959.0 -81800.0 -0.16 -0.1755 -0.9532 3632123 CBKinase1_022204 CCOC(=O)CSc1nnc([nH]1)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K05 compound treatment 1652403.0 -179000.0 -0.34 1530258.0 -164000.0 -0.33 -0.4697 -0.9999 3632124 CBKinase1_022205 CCOC(=O)c1c(NC(=O)CN2CCOCC2)scc1c3ccc(OC)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K06 compound treatment 1936076.0 105000.0 0.2 1698731.0 3980.0 0.01 0.145 0.735 3632125 CBKinase1_022206 COc1ccc(NC(=O)C2(CC3CC4C2)CC(C3)(C4)C(=O)Nc5ccc(OC)cc5OC)c(OC)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K07 mock treatment 2117360.0 286000.0 0.54 1971768.0 277000.0 0.55 0.7715 0.9999 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K08 mock treatment 1892180.0 61100.0 0.11 1895138.0 200000.0 0.4 0.3643 0.8745 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K09 compound treatment 2294746.0 464000.0 0.87 2134111.0 439000.0 0.88 1.2364 1.0 3632126 CBKinase1_022207 COc1ccc2[nH]cc(CCNC(=O)c3cccnc3)c2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K10 compound treatment 1873128.0 42100.0 0.08 1976160.0 281000.0 0.56 0.4535 0.7985 3632127 CBKinase1_022208 Cc1n[nH]c(C)c1SCC(=O)Nc2cccc(Br)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K11 compound treatment 2097936.0 267000.0 0.5 2023143.0 328000.0 0.66 0.8184 0.9911 1366008 CBKinase1_022209 Cn1c(=O)n(C)c2nc(N3CCCCC3)n(CCN)c2c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K12 compound treatment 2126350.0 295000.0 0.55 2224163.0 529000.0 1.06 1.1402 0.9545 3632128 CBKinase1_022210 Fc1ccccc1NC(=O)CSC2CC(=O)N(C2=O)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K13 compound treatment 2077876.0 247000.0 0.46 1920103.0 225000.0 0.45 0.6461 0.9999 3632129 CBKinase1_022211 O=C(CCCN1C(=O)CCC1=O)Nc2ccc3OCCOc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K14 compound treatment 2208676.0 378000.0 0.71 2456858.0 762000.0 1.52 1.5783 0.9394 3632130 CBKinase1_022212 Brc1cccc(NC(=O)CSc2nccc(=O)[nH]2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K15 mock treatment 2074227.0 243000.0 0.46 2005639.0 311000.0 0.62 0.7621 0.9885 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K16 mock treatment 1963937.0 133000.0 0.25 1989429.0 295000.0 0.59 0.5928 0.9269 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K17 compound treatment 2247316.0 416000.0 0.78 1901897.0 207000.0 0.41 0.8453 0.9559 3632131 CBKinase1_022213 CN(CC(=O)Nc1ccccc1NC(=O)C)S(=O)(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K18 compound treatment 1640681.0 -190000.0 -0.36 1734723.0 40000.0 0.08 -0.1963 -0.5358 3632132 CBKinase1_022214 Cc1cc(ccc1NC(=O)C2CC=CCC2C(=O)O)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K19 compound treatment 1544988.0 -286000.0 -0.54 1514420.0 -180000.0 -0.36 -0.6346 -0.9812 3632133 CBKinase1_022215 COc1ccc(cc1NC(=O)CN(C)S(=O)(=O)c2ccccc2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K20 compound treatment 1814589.0 -16500.0 -0.03 1556511.0 -138000.0 -0.28 -0.2173 -0.7814 3632134 CBKinase1_022216 COC(=O)c1ccc(NC(=O)CSc2nc(c([nH]2)c3ccccc3)c4ccccc4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K21 compound treatment 1870484.0 39400.0 0.07 1720502.0 25700.0 0.05 0.0887 0.9843 3632135 CBKinase1_022217 COc1cc(Cl)c(C)cc1NC(=O)CN(C)S(=O)(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K22 compound treatment 1864406.0 33300.0 0.06 1694062.0 -691.0 0.0 0.0433 0.6913 3632136 CBKinase1_022218 COC(=O)Cc1c(C)[nH]c2nc(Cc3ccccc3)nn2c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K23 mock treatment 1624779.0 -206000.0 -0.39 1687931.0 -6820.0 -0.01 -0.2835 -0.7315 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 K24 mock treatment 1495082.0 -336000.0 -0.63 1175788.0 -519000.0 -1.04 -1.1795 -0.9716 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L01 compound treatment 1470149.0 -361000.0 -0.68 1201677.0 -493000.0 -0.99 -1.176 -0.9833 3632137 CBKinase1_022219 Oc1c(cc(Cl)c2cccnc12)C(Nc3ccccn3)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L02 compound treatment 1430703.0 -400000.0 -0.75 1265900.0 -429000.0 -0.86 -1.1376 -0.9979 3632138 CBKinase1_022220 Cc1cc(C)n2nc(NCc3cccc(c3)[N+](=O)[O-])nc2n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L03 compound treatment 1520525.0 -311000.0 -0.58 1524970.0 -170000.0 -0.34 -0.6522 -0.9668 3632139 CBKinase1_022221 COc1cc(cc(I)c1O)C(Nc2ccccn2)c3cc(Cl)c4cccnc4c3O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L04 compound treatment 1685264.0 -146000.0 -0.27 1732135.0 37400.0 0.07 -0.1407 -0.496 3632140 CBKinase1_022222 Cc1c(CCC(=O)O)c(=O)n2c3ccccc3[nH]c2c1C#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L05 compound treatment 1054661.0 -776000.0 -1.46 926869.0 -768000.0 -1.53 -2.1159 -0.9997 3632141 CBKinase1_022223 OC(C(N1CCCCC1)c2ccccc2)C(=O)c3c[nH]c4ccccc34 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L06 compound treatment 1799358.0 -31700.0 -0.06 1607239.0 -87500.0 -0.17 -0.1658 -0.8973 3632142 CBKinase1_022224 COC(=O)c1ccccc1NC(=O)CSc2nnc(o2)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L07 mock treatment 2005796.0 175000.0 0.33 1925160.0 230000.0 0.46 0.5576 0.9862 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L08 mock treatment 1580053.0 -251000.0 -0.47 1737866.0 43100.0 0.09 -0.2723 -0.5684 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L09 compound treatment 1829409.0 -1670.0 0.0 1965790.0 271000.0 0.54 0.3808 0.703 3632143 CBKinase1_022225 CCn1c(SCC(=O)Nc2cccc(Br)c2)nnc1c3ccc(OC)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L10 compound treatment 1427144.0 -404000.0 -0.76 1949417.0 255000.0 0.51 -0.1763 -0.193 3632144 CBKinase1_022226 [O-][N+](=O)c1cccc(CNc2nc3[nH]c(cc(=O)n3n2)c4ccccc4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L11 compound treatment 1537058.0 -294000.0 -0.55 1585517.0 -109000.0 -0.22 -0.5447 -0.9176 3632145 CBKinase1_022227 Oc1c(ccc2cccnc12)C(Nc3ccccn3)c4ccc(OCC#C)cc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L12 compound treatment 1994125.0 163000.0 0.31 1860946.0 166000.0 0.33 0.4513 0.9992 3632146 CBKinase1_022228 CCCc1oc(cc1CN2CCOCC2)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L13 compound treatment 1656899.0 -174000.0 -0.33 2082342.0 388000.0 0.77 0.3166 0.3765 3632147 CBKinase1_022229 COc1cccc(NC(=O)COc2ccccc2C(=O)O)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L14 compound treatment 1499607.0 -331000.0 -0.62 1811598.0 117000.0 0.23 -0.2749 -0.4136 3632148 CBKinase1_022230 COc1cc(NC(=O)COc2ccc(I)cc2)c(cc1OC)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L15 mock treatment 1798751.0 -32300.0 -0.06 1982104.0 287000.0 0.57 0.3632 0.6289 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L16 mock treatment 1696531.0 -135000.0 -0.25 1625743.0 -69000.0 -0.14 -0.2761 -0.9595 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L17 compound treatment 1619046.0 -212000.0 -0.4 2034677.0 340000.0 0.68 0.1989 0.2526 3632149 CBKinase1_022231 CCN(CC(=O)Nc1ccccc1F)S(=O)(=O)c2ccc3ccccc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L18 compound treatment 1298898.0 -532000.0 -1.0 1847983.0 153000.0 0.31 -0.4899 -0.4688 3632150 CBKinase1_022232 CN(Cc1nc2ccccc2n1C)S(=O)(=O)c3ccc(F)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L19 compound treatment 1526748.0 -304000.0 -0.57 1588649.0 -106000.0 -0.21 -0.5539 -0.909 3632151 CBKinase1_022233 COc1ccc(NC(=O)CNC(=O)c2cccc(C)c2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L20 compound treatment 1677560.0 -154000.0 -0.29 1619601.0 -75200.0 -0.15 -0.31 -0.9539 3632152 CBKinase1_022234 COC(=O)c1ccccc1NC(=O)CNC(=O)c2ccc(OC)c(OC)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L21 compound treatment 1160587.0 -670000.0 -1.26 1396910.0 -298000.0 -0.6 -1.311 -0.9415 3632153 CBKinase1_022235 CCN(CC(=O)Nc1cccc(c1)C(F)(F)F)S(=O)(=O)c2ccc(C)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L22 compound treatment 1418616.0 -412000.0 -0.77 1610285.0 -84500.0 -0.17 -0.6669 -0.8415 3632154 CBKinase1_022236 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)Nc2cccnc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L23 mock treatment 1525031.0 -306000.0 -0.57 1253878.0 -441000.0 -0.88 -1.0294 -0.9785 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 L24 mock treatment 1655914.0 -175000.0 -0.33 1478454.0 -216000.0 -0.43 -0.5382 -0.9909 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M01 compound treatment 1499552.0 -332000.0 -0.62 1513862.0 -181000.0 -0.36 -0.6957 -0.9666 3632155 CBKinase1_022237 CC(C)Sc1nc2sc3CCCCc3c2c4nnc(SCC(=O)c5ccccc5)n14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M02 compound treatment 1577074.0 -254000.0 -0.48 1485520.0 -209000.0 -0.42 -0.6329 -0.9979 3632156 CBKinase1_022238 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)Nc2ccc(Oc3ccccc3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M03 compound treatment 1572143.0 -259000.0 -0.49 1672039.0 -22700.0 -0.05 -0.3758 -0.7698 3632157 CBKinase1_022239 O=C(NCc1n[nH]c(=O)c2ccccc12)c3cc4ccccc4oc3=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M04 compound treatment 1803337.0 -27700.0 -0.05 1946183.0 251000.0 0.5 0.3185 0.6305 3632158 CBKinase1_022240 CS(=O)(=O)N(CC(=O)O)c1cc(Cl)c(Cl)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M05 compound treatment 1749260.0 -81800.0 -0.15 1796499.0 102000.0 0.2 0.0352 0.1381 3632159 CBKinase1_022241 COc1ccc(NC(=O)c2c(NC(=O)CN3CCOCC3)scc2c4ccccc4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M06 compound treatment 1707346.0 -124000.0 -0.23 1715936.0 21200.0 0.04 -0.1343 -0.5689 3632160 CBKinase1_022242 OC(=O)c1ccc(cc1)S(=O)(=O)Nc2ccc(O)c(Sc3nc4ccccc4s3)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M07 compound treatment 1691801.0 -139000.0 -0.26 1866951.0 172000.0 0.34 0.0585 0.1353 3632161 CBKinase1_022243 CCOC(=O)c1c(NC(=S)NC(=O)N(C)C)scc1c2ccc(C)o2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M08 compound treatment 1640009.0 -191000.0 -0.36 1877889.0 183000.0 0.37 0.0052 0.0101 3632162 CBKinase1_022244 Cc1c(oc2cc(C)ccc12)C(=O)Nc3sc4CCCCc4c3C(=O)NCc5cccnc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M09 mock treatment 1861921.0 30800.0 0.06 1674119.0 -20600.0 -0.04 0.0118 0.1657 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M10 mock treatment 1537841.0 -293000.0 -0.55 1877039.0 182000.0 0.36 -0.1316 -0.1994 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M11 compound treatment 1753207.0 -77900.0 -0.15 1873344.0 179000.0 0.36 0.149 0.3864 1145891 CBKinase1_022245 Cn1c(=O)n(C)c2nc(N3CCOCC3)n(CCN)c2c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M12 compound treatment 1888787.0 57700.0 0.11 1989648.0 295000.0 0.59 0.4934 0.8233 3632163 CBKinase1_022246 Brc1cccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccccc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M13 mock treatment 1744153.0 -86900.0 -0.16 1963259.0 269000.0 0.54 0.2641 0.4708 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M14 mock treatment 1613842.0 -217000.0 -0.41 1944388.0 250000.0 0.5 0.0644 0.1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M15 compound treatment 1514226.0 -317000.0 -0.59 1679874.0 -14900.0 -0.03 -0.4416 -0.7415 3632164 CBKinase1_022247 CN(CC(=O)Nc1cccc(I)c1)S(=O)(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M16 compound treatment 1712539.0 -119000.0 -0.22 1662628.0 -32100.0 -0.06 -0.2028 -0.8754 3632165 CBKinase1_022248 OC(=O)C1CC=CCC1C(=O)Nc2ccc(Cl)c(c2)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M17 compound treatment 1701947.0 -129000.0 -0.24 1663265.0 -31500.0 -0.06 -0.2159 -0.8621 3632166 CBKinase1_022249 CN(CC(=O)Nc1ccc2ccccc2c1)S(=O)(=O)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M18 compound treatment 1468252.0 -363000.0 -0.68 1664929.0 -29800.0 -0.06 -0.5238 -0.7661 3632167 CBKinase1_022250 CC(Oc1ccc2c(C)cc(=O)oc2c1)C(=O)Nc3ccc(cc3)N4CCOCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M19 compound treatment 1320643.0 -510000.0 -0.96 1510138.0 -185000.0 -0.37 -0.9385 -0.914 3632168 CBKinase1_022251 COc1cc(NC(=O)CN(C)S(=O)(=O)c2ccccc2)c(OC)cc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M20 compound treatment 1671444.0 -160000.0 -0.3 1670776.0 -24000.0 -0.05 -0.2458 -0.8099 3632169 CBKinase1_022252 CC1(C)CC2=C(C(=O)C1)C(NC(=O)c3ccc(Cl)cc3Cl)(C(=O)N2Cc4cccnc4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M21 compound treatment 1457126.0 -374000.0 -0.7 1588495.0 -106000.0 -0.21 -0.6466 -0.8816 3632170 CBKinase1_022253 CN(Cc1nc(no1)c2ccccc2)S(=O)(=O)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M22 compound treatment 507430.0 -1320000.0 -2.48 648964.0 -1050000.0 -2.09 -3.2351 -0.9963 3632171 CBKinase1_022254 Cc1cc(=O)n2c3ccccc3n(CC(O)CNCc4ccccc4)c2c1C#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M23 compound treatment 1091550.0 -740000.0 -1.39 1834578.0 140000.0 0.28 -0.7841 -0.5537 3632172 CBKinase1_022255 Cc1ccc2oc(nc2c1)c3ccc(NC(=O)Cn4c(=O)oc5ccccc45)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 M24 compound treatment 1252611.0 -578000.0 -1.09 1449286.0 -245000.0 -0.49 -1.1148 -0.9355 3632173 CBKinase1_022256 COc1ccc(cc1OC)C(=O)NCC(=O)Nc2ccccc2C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N01 compound treatment 1039042.0 -792000.0 -1.49 1256540.0 -438000.0 -0.88 -1.6707 -0.9681 3632174 CBKinase1_022257 [O-][N+](=O)c1ccccc1NC(=O)C2(CCN(CC2)S(=O)(=O)c3ccccc3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N02 compound treatment 1427667.0 -403000.0 -0.76 1476671.0 -218000.0 -0.44 -0.8437 -0.9656 3632175 CBKinase1_022258 COC(=O)Cc1c(C)[nH]c2nc(NCc3c(F)cccc3Cl)nn2c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N03 compound treatment 1491711.0 -339000.0 -0.64 1484926.0 -210000.0 -0.42 -0.747 -0.9794 3632176 CBKinase1_022259 Clc1ccc(OCCCC(=O)Nc2ccc3C(=O)NC(=O)c3c2)c(Cl)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N04 compound treatment 1604915.0 -226000.0 -0.42 1349768.0 -345000.0 -0.69 -0.7878 -0.9729 3632177 CBKinase1_022260 O=C(CN1CCCCC1)Nc2sc3CCCCc3c2C(=O)Nc4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N05 compound treatment 1581047.0 -250000.0 -0.47 1770989.0 76200.0 0.15 -0.2242 -0.4542 3632178 CBKinase1_022261 CCn1c(SCC(=O)c2ccc(OC)cc2)nnc1c3ccc(Cl)cc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N06 compound treatment 1552502.0 -279000.0 -0.52 1481202.0 -214000.0 -0.43 -0.6716 -0.9949 3632179 CBKinase1_022262 COc1ccc(OCC(=O)Nc2cccc(c2)c3cnc4ccccc4n3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N07 compound treatment 1641016.0 -190000.0 -0.36 1675560.0 -19200.0 -0.04 -0.2794 -0.7786 3632180 CBKinase1_022263 OC(C(N1CCOCC1)c2ccccc2)C(=O)c3c[nH]c4ccccc34 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N08 compound treatment 1739709.0 -91400.0 -0.17 1631738.0 -63000.0 -0.13 -0.2103 -0.9885 3632181 CBKinase1_022264 Fc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)NCc3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N09 mock treatment 1848539.0 17500.0 0.03 1752251.0 57500.0 0.11 0.1044 0.8739 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N10 mock treatment 1565578.0 -265000.0 -0.5 1758119.0 63400.0 0.13 -0.2629 -0.5112 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N11 compound treatment 1527650.0 -303000.0 -0.57 1734122.0 39400.0 0.08 -0.3472 -0.6037 3632182 CBKinase1_022265 COC(=O)c1ccc(C(=O)OC)c(NC(=O)COc2cc(C)c(C)cc2C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N12 compound treatment 1489410.0 -342000.0 -0.64 1800400.0 106000.0 0.21 -0.3042 -0.4505 3632183 CBKinase1_022266 CCN(CC(=O)Nc1cc(Cl)ccc1OC)S(=O)(=O)c2ccc(C)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N13 mock treatment 1662338.0 -169000.0 -0.32 1730465.0 35700.0 0.07 -0.1735 -0.5344 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N14 mock treatment 1612554.0 -219000.0 -0.41 2748185.0 1050000.0 2.11 1.1987 0.5588 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N15 compound treatment 1634581.0 -196000.0 -0.37 1675241.0 -19500.0 -0.04 -0.2884 -0.7775 3632184 CBKinase1_022267 Clc1ccccc1NC(=O)c2ccc(OCC(=O)Nc3ccc(Oc4ccccc4)cc3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N16 compound treatment 1473889.0 -357000.0 -0.67 1653948.0 -40800.0 -0.08 -0.5318 -0.7873 3632185 CBKinase1_022268 FC(F)(F)c1ccccc1NC(=O)COc2ccc(cc2)C(=O)Nc3ccccc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N17 compound treatment 1632817.0 -198000.0 -0.37 1810789.0 116000.0 0.23 -0.0992 -0.2262 3632186 CBKinase1_022269 CC(=O)c1cc(C)ccc1OC(=O)CCN2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N18 compound treatment 1526953.0 -304000.0 -0.57 1674345.0 -20400.0 -0.04 -0.4326 -0.7557 3632187 CBKinase1_022270 COc1ccc(OC)c(c1)S(=O)(=O)N(C)CC(=O)N2CCN(CC2)c3cccc(Cl)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N19 compound treatment 1679422.0 -152000.0 -0.28 1684296.0 -10500.0 -0.02 -0.2161 -0.757 3632188 CBKinase1_022271 COC(=O)CSc1nc(NC(C)C)nc(n1)N2CCOCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N20 compound treatment 1669780.0 -161000.0 -0.3 1625046.0 -69700.0 -0.14 -0.3126 -0.9379 3632189 CBKinase1_022272 CC(Oc1ccc2c(C)cc(=O)oc2c1)C(=O)Nc3sc4CCCCc4c3C#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N21 compound treatment 1091279.0 -740000.0 -1.39 1683329.0 -11400.0 -0.02 -0.9982 -0.7186 3632190 CBKinase1_022273 COc1ccc(cc1NC(=O)CS(=O)(=O)c2ccc(C)cc2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N22 compound treatment 1384853.0 -446000.0 -0.84 1619422.0 -75300.0 -0.15 -0.6988 -0.821 3632191 CBKinase1_022274 COc1ccccc1NC(=O)CSc2nc(cc(=O)[nH]2)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N23 compound treatment 1480137.0 -351000.0 -0.66 1544878.0 -150000.0 -0.3 -0.6777 -0.9364 3632192 CBKinase1_022275 COc1ccccc1CNc2nc3[nH]c(C)cc(=O)n3n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 N24 compound treatment 1300805.0 -530000.0 -1.0 1419954.0 -275000.0 -0.55 -1.0923 -0.9607 3632193 CBKinase1_022276 CC1(C)CC(CC(C)(C)N1)NC(=O)C(=O)NCC2COc3ccccc3O2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O01 compound treatment 938060.0 -893000.0 -1.68 978313.0 -716000.0 -1.43 -2.198 -0.9969 3632194 CBKinase1_022277 CC1(C)Cc2c(CO1)sc3c2c4ncnn4c5nnc(SCC(=O)c6ccc(Br)cc6)n53 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O02 compound treatment 1527664.0 -303000.0 -0.57 1462402.0 -232000.0 -0.46 -0.7312 -0.9949 3632195 CBKinase1_022278 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)Nc2cccc(c2)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O03 compound treatment 1528188.0 -303000.0 -0.57 1406834.0 -288000.0 -0.58 -0.809 -1.0 3632196 CBKinase1_022279 COc1ccc(cc1)n2c(C)c(C(=O)C)c3cc(OCC(=O)N)ccc23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O04 compound treatment 1568069.0 -263000.0 -0.49 1476423.0 -218000.0 -0.44 -0.6577 -0.9981 3632197 CBKinase1_022280 COC(=O)CN(c1ccccc1)S(=O)(=O)c2ccc(F)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O05 compound treatment 1648922.0 -182000.0 -0.34 1313778.0 -381000.0 -0.76 -0.7802 -0.9347 1648310 CBKinase1_022281 CCOC(=O)c1c(NC(=O)CN2C(=O)c3ccccc3C2=O)scc1c4ccc(C)o4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O06 compound treatment 1708338.0 -123000.0 -0.23 1215287.0 -479000.0 -0.96 -0.8406 -0.8528 3632198 CBKinase1_022282 OCCCN1C(c2c(oc3ccccc3c2=O)C1=O)c4ccc(cc4)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O07 compound treatment 1295613.0 -535000.0 -1.01 1331055.0 -364000.0 -0.73 -1.2248 -0.9873 3632199 CBKinase1_022283 CC(C)(O)C#Cc1ccccc1C(=O)NC(CC(=O)O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O08 compound treatment 2120481.0 289000.0 0.54 2038877.0 344000.0 0.69 0.8705 0.9932 3632200 CBKinase1_022284 CC1CCc2c(C(=O)NC3CCS(=O)(=O)C3)c(NC(=O)c4oc5ccc(Cl)cc5c4C)sc2C1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O09 compound treatment 1342335.0 -489000.0 -0.92 1306842.0 -388000.0 -0.78 -1.197 -0.9965 3632201 CBKinase1_022285 CC(=O)c1c(C)n(Cc2ccccc2)c3c(Cl)c(Cl)c(Cl)c(OCC(=O)O)c13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O10 compound treatment 1320930.0 -510000.0 -0.96 1197537.0 -497000.0 -0.99 -1.3799 -0.9998 3632202 CBKinase1_022286 CCOc1ccccc1NC(=O)CSc2c(C)n[nH]c2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O11 mock treatment 1129290.0 -702000.0 -1.32 1456051.0 -239000.0 -0.48 -1.269 -0.9056 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O12 mock treatment 1225113.0 -606000.0 -1.14 1333693.0 -361000.0 -0.72 -1.3147 -0.9759 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O13 compound treatment 1176245.0 -655000.0 -1.23 1597064.0 -97700.0 -0.2 -1.0073 -0.8093 3632203 CBKinase1_022287 CCn1c2ccccc2c3cc(NC(=O)CCCN4C(=O)CCC4=O)ccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O14 compound treatment 1442847.0 -388000.0 -0.73 1431182.0 -264000.0 -0.53 -0.8879 -0.9873 3632204 CBKinase1_022288 COc1ccc(CNc2nc3[nH]c(cc(=O)n3n2)c4ccccc4)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O15 compound treatment 1517953.0 -313000.0 -0.59 1276531.0 -418000.0 -0.84 -1.0067 -0.9852 3632205 CBKinase1_022289 CN(CC(=O)Nc1ccc(Nc2ccccc2)cc1)S(=O)(=O)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O16 compound treatment 1386687.0 -444000.0 -0.83 1248152.0 -447000.0 -0.89 -1.2211 -0.9994 3632206 CBKinase1_022290 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)Nc2ccc(F)c(F)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O17 compound treatment 1262368.0 -569000.0 -1.07 1397775.0 -297000.0 -0.59 -1.1747 -0.9616 3632207 CBKinase1_022291 CN(CC(=O)Nc1cccnc1)S(=O)(=O)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O18 compound treatment 1629396.0 -202000.0 -0.38 1380341.0 -314000.0 -0.63 -0.7121 -0.9706 1652635 CBKinase1_022292 CCn1c(nc2ccccc12)c3nonc3NC(=O)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O19 compound treatment 1540004.0 -291000.0 -0.55 1312384.0 -382000.0 -0.76 -0.9268 -0.9865 3632208 CBKinase1_022293 COc1cc(NC(=O)CN(C)S(=O)(=O)c2ccccc2)cc(OC)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O20 compound treatment 990182.0 -841000.0 -1.58 1197560.0 -497000.0 -0.99 -1.8189 -0.9751 3632209 CBKinase1_022294 OC1(CC(=O)c2ccncc2)C(=O)N(CCc3ccccc3)c4ccc(Br)cc41 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O21 compound treatment 973953.0 -857000.0 -1.61 1233567.0 -461000.0 -0.92 -1.7896 -0.965 3632210 CBKinase1_022295 COc1ccc(cc1OC)c2noc(CN(C)S(=O)(=O)c3ccccc3)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O22 compound treatment 1347879.0 -483000.0 -0.91 1364536.0 -330000.0 -0.66 -1.1081 -0.9878 3632211 CBKinase1_022296 O=C(Nc1cccc(c1)C(=O)NCc2ccco2)c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O23 compound treatment 1281575.0 -550000.0 -1.03 1242585.0 -452000.0 -0.9 -1.3685 -0.9978 3632212 CBKinase1_022297 CCOC(=O)c1c(C)c(sc1NC(=O)Cn2c(=O)oc3ccccc23)C(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 O24 compound treatment 1162713.0 -668000.0 -1.25 1153687.0 -541000.0 -1.08 -1.6519 -0.9973 3632213 CBKinase1_022298 COc1ccc(CNC(=O)C2CCCCC2C(=O)O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P01 compound treatment 793100.0 -1040000.0 -1.95 742799.0 -952000.0 -1.9 -2.7233 -0.9999 3632214 CBKinase1_022299 Brc1ccc(cc1)C(=O)Nc2cccc(c2)C(=O)NCc3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P02 compound treatment 1134591.0 -696000.0 -1.31 890803.0 -804000.0 -1.61 -2.0608 -0.9948 3632215 CBKinase1_022300 COC(=O)c1c(NC(=O)COc2ccccc2)sc(C)c1c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P03 compound treatment 911982.0 -919000.0 -1.73 1053616.0 -641000.0 -1.28 -2.1262 -0.9893 3632216 CBKinase1_022301 O=C(Nc1ccc(cc1)C(=O)OCc2cccc(c2)C(=O)c3ccccc3)c4ccco4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P04 compound treatment 1066506.0 -765000.0 -1.44 962854.0 -732000.0 -1.46 -2.0493 -1.0 3632217 CBKinase1_022302 OC(=O)c1ccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccccc4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P05 compound treatment 1160190.0 -671000.0 -1.26 1215707.0 -479000.0 -0.96 -1.5676 -0.9908 3632218 CBKinase1_022303 OC(=O)c1[nH]c2ccccc2c1C(c3c([nH]c4ccccc34)C(=O)O)c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P06 compound treatment 1012872.0 -818000.0 -1.54 1024486.0 -670000.0 -1.34 -2.0334 -0.9977 3632219 CBKinase1_022304 CCC1(C)Cc2c(CO1)sc3nc(SC)nc(SCC(=O)Nc4cccc(Cl)c4)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P07 compound treatment 1229604.0 -601000.0 -1.13 1081150.0 -614000.0 -1.23 -1.6656 -0.9991 3632220 CBKinase1_022305 COC(=O)c1cc(NC(=O)COc2ccc(I)cc2)cc(c1)C(=O)OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P08 compound treatment 1069366.0 -762000.0 -1.43 1030825.0 -664000.0 -1.33 -1.9495 -0.9993 3632221 CBKinase1_022306 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2cccc(c2)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P09 compound treatment 1306260.0 -525000.0 -0.99 1185598.0 -509000.0 -1.02 -1.4163 -0.9999 3632222 CBKinase1_022307 COC(=O)c1ccc(C(=O)OC)c(NC(=O)COc2ccc(I)cc2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P10 compound treatment 1149848.0 -681000.0 -1.28 1269257.0 -425000.0 -0.85 -1.5057 -0.9803 3632223 CBKinase1_022308 CCOC(=O)c1c(C)c(C)sc1NC(=O)COc2ccccc2Br 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P11 mock treatment 1199088.0 -632000.0 -1.19 1276773.0 -418000.0 -0.84 -1.4297 -0.9853 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P12 mock treatment 1232999.0 -598000.0 -1.12 1495924.0 -199000.0 -0.4 -1.0749 -0.9025 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P13 compound treatment 1091906.0 -739000.0 -1.39 1238265.0 -456000.0 -0.91 -1.6264 -0.9793 3632224 CBKinase1_022309 COc1ccc(OC)c(NC(=O)c2ccc(Cl)c(c2)S(=O)(=O)Nc3ccc(C)cc3C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P14 compound treatment 1123868.0 -707000.0 -1.33 1226867.0 -468000.0 -0.94 -1.6001 -0.9853 3632225 CBKinase1_022310 CC(=O)C1=C(C)N(Cc2ccco2)C(=O)C1(NC(=O)C3CCCCC3)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P15 compound treatment 1336371.0 -495000.0 -0.93 1800251.0 105000.0 0.21 -0.5076 -0.533 3632226 CBKinase1_022311 CS(=O)(=O)N(CC(=O)Nc1ccc2OCCOc2c1)c3cc(Cl)c(Cl)cc3Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P16 compound treatment 1264864.0 -566000.0 -1.06 1358344.0 -336000.0 -0.67 -1.2271 -0.9756 3632227 CBKinase1_022312 COc1cccc(OCc2nc(no2)c3ccccc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P17 compound treatment 1193992.0 -637000.0 -1.2 1021206.0 -674000.0 -1.35 -1.7976 -0.9983 3632228 CBKinase1_022313 FC(F)(F)C1(NC(=O)N(Cc2cccnc2)C1=O)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P18 compound treatment 1119970.0 -711000.0 -1.33 1202320.0 -492000.0 -0.98 -1.6399 -0.9888 3632229 CBKinase1_022314 COc1ccc(cc1S(=O)(=O)NCC2CCCO2)C(C)(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P19 compound treatment 1090613.0 -740000.0 -1.39 1084212.0 -611000.0 -1.22 -1.8458 -0.9979 3632230 CBKinase1_022315 [O-][N+](=O)c1ccccc1OC(=O)CCN2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P20 compound treatment 941003.0 -890000.0 -1.67 1078217.0 -617000.0 -1.23 -2.0529 -0.9888 3632231 CBKinase1_022316 Cc1cccc(OCC(=O)Nc2ccc3n(C)c(CN4CCCCC4)nc3c2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P21 compound treatment 900550.0 -931000.0 -1.75 1117653.0 -577000.0 -1.15 -2.0509 -0.9797 3632232 CBKinase1_022317 COC(=O)c1ccc(NC(=O)CSc2nnc([nH]2)c3ccncc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P22 compound treatment 970889.0 -860000.0 -1.61 1406675.0 -288000.0 -0.58 -1.549 -0.9035 3632233 CBKinase1_022318 COc1cc(C)c(Cl)cc1S(=O)(=O)NCc2ccco2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P23 compound treatment 1032619.0 -798000.0 -1.5 985531.0 -709000.0 -1.42 -2.0623 -0.9996 3040636 CBKinase1_022319 OC(Cn1ccc2ccccc12)Cn3cnc4ccccc34 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2393 P24 compound treatment 894211.0 -937000.0 -1.76 808320.0 -886000.0 -1.77 -2.4965 -1.0 3632234 CBKinase1_022320 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2ccc(F)c(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A01 compound treatment 1253470.0 -608000.0 -1.14 1235294.0 -492000.0 -0.98 -1.5029 -0.9972 3632235 CBKinase1_022321 Cc1cc(C)c2nc(cc(C(=O)NCc3ccc(cc3)S(=O)(=O)N)c2c1)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A02 compound treatment 1157033.0 -705000.0 -1.32 1309208.0 -418000.0 -0.84 -1.5264 -0.9754 3632236 CBKinase1_022322 COc1ccc(OC)c(c1)S(=O)(=O)N(C)CC(=O)N2CCN(CC2)c3ccccc3F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A03 compound treatment 1287044.0 -575000.0 -1.08 1617772.0 -109000.0 -0.22 -0.9177 -0.8335 3632237 CBKinase1_022323 CC1CCc2c(C(=O)N)c(NC(=O)c3cc(nc4c(Cl)cccc34)c5ccccn5)sc2C1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A04 compound treatment 1223073.0 -639000.0 -1.2 1477157.0 -250000.0 -0.5 -1.2014 -0.9247 3632238 CBKinase1_022324 Cc1cc(=O)n2nc(NCc3cccc(c3)[N+](=O)[O-])nc2[nH]1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A05 compound treatment 1343376.0 -518000.0 -0.97 1579326.0 -148000.0 -0.3 -0.8973 -0.8821 3632239 CBKinase1_022325 O=C(NC1CCCC1)c2c(NC(=O)c3cc(nc4ccccc34)c5cccnc5)sc6CCCCc26 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A06 compound treatment 1332630.0 -529000.0 -0.99 1558572.0 -169000.0 -0.34 -0.9409 -0.8968 3632240 CBKinase1_022326 COc1ccccc1C(=O)NC2(C(=O)N(Cc3ccco3)C4=C2C(=O)CC(C)(C)C4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A07 compound treatment 1483302.0 -379000.0 -0.71 1638365.0 -88900.0 -0.18 -0.6281 -0.8575 3632241 CBKinase1_022327 CCOC(=O)c1sc(NC(=O)c2cc(nc3ccccc23)c4ccccn4)c(C(=O)OCC)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A08 compound treatment 1183922.0 -678000.0 -1.27 1212577.0 -515000.0 -1.03 -1.6273 -0.9944 3632242 CBKinase1_022328 CCN(CC(=O)Nc1ccccc1C(F)(F)F)S(=O)(=O)c2ccc(C)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A09 compound treatment 1695258.0 -167000.0 -0.31 1574310.0 -153000.0 -0.31 -0.4373 -0.9999 3632243 CBKinase1_022329 Clc1ccc2nc(cc(C(=O)NCCCn3ccnc3)c2c1)c4cccnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A10 compound treatment 1614257.0 -248000.0 -0.46 1786480.0 59200.0 0.12 -0.2449 -0.5107 3632244 CBKinase1_022330 CCn1c(SCC(=O)Nc2ccccc2N3CCOCC3)nnc1c4ccccc4O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A11 compound treatment 1366856.0 -495000.0 -0.93 1687915.0 -39300.0 -0.08 -0.7127 -0.7642 3632245 CBKinase1_022331 Brc1ccc2nc(cc(C(=O)NCCCn3ccnc3)c2c1)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A12 compound treatment 1691598.0 -170000.0 -0.32 1542415.0 -185000.0 -0.37 -0.4872 -0.9974 3632246 CBKinase1_022332 Cc1ccc2NC(=O)C(O)(CC(=O)c3ccccc3[N+](=O)[O-])c2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A13 mock treatment 1469620.0 -392000.0 -0.74 1607971.0 -119000.0 -0.24 -0.6892 -0.8906 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A14 mock treatment 1406896.0 -455000.0 -0.85 1505748.0 -222000.0 -0.44 -0.917 -0.9532 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A15 compound treatment 2105750.0 244000.0 0.46 1803373.0 76100.0 0.15 0.4314 0.894 3632247 CBKinase1_022333 CC(=O)c1ccc(NC(=O)CSc2nnc([nH]2)c3ccncc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A16 compound treatment 1298772.0 -563000.0 -1.06 1754858.0 27600.0 0.06 -0.7084 -0.6693 3632248 CBKinase1_022334 Cc1cc(ccc1Br)N(CC(=O)Nc2ccccc2C(=O)N3CCOCC3)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A17 compound treatment 1928448.0 66600.0 0.13 1409675.0 -318000.0 -0.63 -0.3604 -0.557 3632249 CBKinase1_022335 [O-][N+](=O)c1ccc(cc1NCc2ccco2)N3CCN(CC3)S(=O)(=O)c4cccs4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A18 compound treatment 1855399.0 -6410.0 -0.01 1431718.0 -296000.0 -0.59 -0.4262 -0.7214 3632250 CBKinase1_022336 Cc1cccc(OCCCC(=O)Nc2ccc3OCCOc3c2)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A19 compound treatment 1358934.0 -503000.0 -0.94 1507071.0 -220000.0 -0.44 -0.9788 -0.9397 3632251 CBKinase1_022337 CN1CCN(CC1)c2ccccc2NC(=O)COc3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A20 compound treatment 1106671.0 -755000.0 -1.42 1543067.0 -184000.0 -0.37 -1.2628 -0.8621 3632252 CBKinase1_022338 CSc1nsc(SCC(=O)N2CCc3ccccc23)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A21 compound treatment 1482891.0 -379000.0 -0.71 1583757.0 -144000.0 -0.29 -0.7058 -0.9202 3632253 CBKinase1_022339 COc1ccccc1NC(=O)COc2ccc3c(cc(=O)oc3c2C)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A22 compound treatment 1172808.0 -689000.0 -1.29 1594885.0 -132000.0 -0.26 -1.1017 -0.8345 3632254 CBKinase1_022340 Clc1ccc(NC(=O)CSc2nnc3n(c4ccccc4)c5ccccc5n23)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A23 compound treatment 1181940.0 -680000.0 -1.28 1636034.0 -91200.0 -0.18 -1.0315 -0.8 3632255 CBKinase1_022341 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2cccc(SC)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 A24 compound treatment 1157516.0 -704000.0 -1.32 1614611.0 -113000.0 -0.23 -1.0941 -0.8158 3632256 CBKinase1_022342 COC(=O)c1cccc(NC(=O)C(C)Oc2ccc3c(C)cc(=O)oc3c2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B01 compound treatment 1354688.0 -507000.0 -0.95 1301035.0 -426000.0 -0.85 -1.2756 -0.9985 3632257 CBKinase1_022343 COC(=O)c1ccccc1NC(=O)CSc2nnc(c3ccccc3O)n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B02 compound treatment 1693730.0 -168000.0 -0.32 1468061.0 -259000.0 -0.52 -0.5895 -0.9717 3632258 CBKinase1_022344 COC(=O)C1=C(C)NC(=O)C1(NS(=O)(=O)c2ccc(C)cc2)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B03 compound treatment 1586150.0 -276000.0 -0.52 1870883.0 144000.0 0.29 -0.163 -0.2754 3632259 CBKinase1_022345 Cc1c(Cl)cccc1NC(=O)CNC(=O)c2ccco2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B04 compound treatment 1454383.0 -407000.0 -0.76 1848002.0 121000.0 0.24 -0.3702 -0.4616 3632260 CBKinase1_022346 COc1ccc(NC(=O)C(C)Oc2cc(C)c(Cl)c(C)c2)c(c1)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B05 compound treatment 1614983.0 -247000.0 -0.46 1821186.0 93900.0 0.19 -0.1949 -0.3899 3632261 CBKinase1_022347 CC(Oc1ccc(cc1)C(=O)Nc2cccc(C)c2C)C(=O)Nc3ccc(Br)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B06 compound treatment 1382128.0 -480000.0 -0.9 1929681.0 202000.0 0.4 -0.3507 -0.3552 3632262 CBKinase1_022348 Cc1ccc2n(Cc3ccccc3)c4nc(SCCN5CCOCC5)nnc4c2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B07 compound treatment 1121320.0 -740000.0 -1.39 1710467.0 -16800.0 -0.03 -1.0067 -0.724 3632263 CBKinase1_022349 COc1ccc(C)cc1S(=O)(=O)N2CCC(CC2)C(=O)Nc3ccccc3Sc4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B08 compound treatment 1804693.0 -57100.0 -0.11 1957062.0 230000.0 0.46 0.2489 0.5278 3632264 CBKinase1_022350 CC(=O)c1cccc(NC(=O)CSc2nc(nc(n2)N3CCCCC3)N4CCCCC4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B09 compound treatment 1638364.0 -223000.0 -0.42 1648577.0 -78700.0 -0.16 -0.4078 -0.9103 3632265 CBKinase1_022351 CCN(CC(=O)Nc1ccc(C)c(Cl)c1)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B10 compound treatment 1446830.0 -415000.0 -0.78 1525076.0 -202000.0 -0.4 -0.8366 -0.9533 3632266 CBKinase1_022352 COC(=O)c1ccccc1NC(=O)CNC(=O)c2ccc(cc2)C(C)(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B11 compound treatment 1472218.0 -390000.0 -0.73 1869515.0 142000.0 0.28 -0.3161 -0.4029 3632267 CBKinase1_022353 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2ccccc2Br 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B12 compound treatment 1365388.0 -496000.0 -0.93 1527625.0 -200000.0 -0.4 -0.9411 -0.9283 3632268 CBKinase1_022354 CSc1cccc(NC(=O)C(C)NS(=O)(=O)c2ccc(F)cc2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B13 mock treatment 1628774.0 -233000.0 -0.44 1874801.0 148000.0 0.29 -0.1008 -0.1911 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B14 mock treatment 1503067.0 -359000.0 -0.67 1612772.0 -114000.0 -0.23 -0.638 -0.897 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B15 compound treatment 1476657.0 -385000.0 -0.72 1602439.0 -125000.0 -0.25 -0.6877 -0.8991 3632269 CBKinase1_022355 CN1CCN(CCCNC(=O)Nc2ccccc2C)CC1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B16 compound treatment 2080461.0 219000.0 0.41 1957724.0 230000.0 0.46 0.616 0.9983 3632270 CBKinase1_022356 O=C(Nc1cccc(OC2=NS(=O)(=O)c3ccccc23)c1)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B17 compound treatment 1711689.0 -150000.0 -0.28 1771973.0 44700.0 0.09 -0.1361 -0.4603 3632271 CBKinase1_022357 Cc1ccc(cc1NC(=O)CSc2nnnn2C3CC4CCC3C4)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B18 compound treatment 815442.0 -1050000.0 -1.96 1088403.0 -639000.0 -1.28 -2.2919 -0.9782 3632272 CBKinase1_022358 Cc1ccc(C)c(c1)C(Nc2ccccn2)c3cc(Cl)c4cccnc4c3O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B19 compound treatment 1663999.0 -198000.0 -0.37 1671355.0 -55900.0 -0.11 -0.3416 -0.8809 3632273 CBKinase1_022359 COc1ccccc1NC(=O)CSc2nc3cc4ccccc4cc3[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B20 compound treatment 1635856.0 -226000.0 -0.42 1866975.0 140000.0 0.28 -0.1025 -0.2018 3632274 CBKinase1_022360 OC(=O)c1cccc(NC(=O)C2(CCN(CC2)S(=O)(=O)c3ccccc3)c4ccccc4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B21 compound treatment 1152702.0 -709000.0 -1.33 2008282.0 281000.0 0.56 -0.5442 -0.3766 3632275 CBKinase1_022361 CCOc1ccc(C)cc1S(=O)(=O)NCc2ccco2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B22 compound treatment 1199142.0 -663000.0 -1.24 1858479.0 131000.0 0.26 -0.6942 -0.546 3632276 CBKinase1_022362 O=C(CCN1C(=O)c2ccccc2C1=O)Nc3ccc(cc3)c4nc5ccccc5[nH]4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B23 compound treatment 1557312.0 -305000.0 -0.57 1826369.0 99100.0 0.2 -0.2642 -0.4366 3632277 CBKinase1_022363 COc1ccc(NC(=O)CSc2nnnn2c3ccc(OC)cc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 B24 compound treatment 1149870.0 -712000.0 -1.34 1664867.0 -62400.0 -0.12 -1.0333 -0.7697 3632278 CBKinase1_022364 O=C(OCc1ccco1)c2ccc(cc2)S(=O)(=O)N3CCCCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C01 compound treatment 1700411.0 -161000.0 -0.3 1414682.0 -313000.0 -0.62 -0.656 -0.9448 3632279 CBKinase1_022365 Cc1nn(C)c(C)c1CNC(=O)c2cc(nc3c(C)cccc23)c4ccccc4Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C02 compound treatment 1762552.0 -99300.0 -0.19 1821654.0 94400.0 0.19 0.0016 0.0062 3632280 CBKinase1_022366 CCOc1ccccc1CNc2nc3nc(C)c(Cl)c(C)n3n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C03 compound treatment 1948489.0 86700.0 0.16 1732426.0 5160.0 0.01 0.1224 0.7505 3632281 CBKinase1_022367 Cc1sc(NC(=O)c2cc(nc3ccc(Cl)cc23)c4cccnc4)c(C(=O)N)c1c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C04 compound treatment 1948716.0 86900.0 0.16 2072542.0 345000.0 0.69 0.6033 0.8508 3632282 CBKinase1_022368 COc1ccc(Oc2ccc(NC(=O)C(C)N3C(=O)C4C(C5C=CC4C6CC65)C3=O)cc2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C05 compound treatment 1912255.0 50400.0 0.09 1921735.0 194000.0 0.39 0.3418 0.8544 3632283 CBKinase1_022369 COC(=O)c1ccccc1NC(=O)c2cc(nc3c(C)c(Cl)ccc23)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C06 compound treatment 1742445.0 -119000.0 -0.22 1854592.0 127000.0 0.25 0.0215 0.0634 3632284 CBKinase1_022370 COc1ccccc1NC(=O)CSc2nnc(o2)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C07 compound treatment 1683132.0 -179000.0 -0.34 1838486.0 111000.0 0.22 -0.08 -0.1988 3632285 CBKinase1_022371 CCc1c(C)sc(NC(=O)c2cc(nc3ccc(Cl)cc23)c4cccnc4)c1C(=O)N5CCOCC5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C08 compound treatment 2007822.0 146000.0 0.27 1908537.0 181000.0 0.36 0.45 0.9905 3632286 CBKinase1_022372 COc1cccc(OC)c1C(=O)Nc2cccc(c2)c3nc4ncccc4o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C09 compound treatment 1910073.0 48300.0 0.09 1919273.0 192000.0 0.38 0.3354 0.8507 3632287 CBKinase1_022373 Cc1cc(nn1CCCNC(=O)c2cc(nc3ccccc23)c4ccccc4)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C10 compound treatment 1715005.0 -147000.0 -0.28 1910669.0 183000.0 0.37 0.0643 0.1402 3632288 CBKinase1_022374 CN(c1cccc(NC(=O)c2ccc(C)c(c2)S(=O)(=O)Nc3cc(C)ccc3C)c1)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C11 mock treatment 2053883.0 192000.0 0.36 1721864.0 -5400.0 -0.01 0.2473 0.6856 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C12 mock treatment 1617740.0 -244000.0 -0.46 2072498.0 345000.0 0.69 0.1639 0.1979 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C13 compound treatment 1672815.0 -189000.0 -0.35 1806906.0 79600.0 0.16 -0.1383 -0.3557 3632289 CBKinase1_022375 CC(=O)c1cccc(c1)N(CC(=O)Nc2ccccc2C)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C14 compound treatment 1804579.0 -57200.0 -0.11 1978439.0 251000.0 0.5 0.279 0.5435 3632290 CBKinase1_022376 CCn1c(SCC(=O)Nc2cccc(F)c2)nnc1c3ccc(OC)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C15 mock treatment 1927100.0 65300.0 0.12 1892122.0 165000.0 0.33 0.3197 0.9093 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C16 mock treatment 2035202.0 173000.0 0.33 1819607.0 92300.0 0.18 0.3607 0.9639 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C17 compound treatment 1439858.0 -422000.0 -0.79 1870555.0 143000.0 0.29 -0.3576 -0.4246 3632291 CBKinase1_022377 COc1ccccc1NC(=O)COc2ccc(Br)cc2CO 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C18 compound treatment 1824553.0 -37300.0 -0.07 1979439.0 252000.0 0.5 0.3069 0.6032 3632292 CBKinase1_022378 COc1ccc(C)cc1NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C19 compound treatment 1751937.0 -110000.0 -0.21 1468071.0 -259000.0 -0.52 -0.5122 -0.9185 1206916 CBKinase1_022379 CC(C)c1ccc(C)cc1OCC(=O)Nc2sc3CC(C)CCc3c2C(=O)N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C20 compound treatment 1675703.0 -186000.0 -0.35 1824860.0 97600.0 0.2 -0.1091 -0.2727 3632293 CBKinase1_022380 CCCN(Cc1cc2cccc(C)c2nc1O)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C21 compound treatment 1795047.0 -66800.0 -0.13 1554851.0 -172000.0 -0.34 -0.3323 -0.9062 3632294 CBKinase1_022381 CC(=O)c1ccc(NC(=O)CSc2nc(N)n[nH]2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C22 compound treatment 1789344.0 -72500.0 -0.14 1660633.0 -66600.0 -0.13 -0.1904 -0.9999 1430552 CBKinase1_022382 COC(=O)c1c(NC(=O)COc2cc(C)ccc2C)sc3CCCc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C23 compound treatment 1534768.0 -327000.0 -0.61 1565188.0 -162000.0 -0.32 -0.6632 -0.9554 3632295 CBKinase1_022383 COc1ccccc1n2c(SCC(=O)N(c3ccccc3)c4ccccc4)nc5ccccc5c2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 C24 compound treatment 1508396.0 -353000.0 -0.66 1617996.0 -109000.0 -0.22 -0.6236 -0.8927 3632296 CBKinase1_022384 CCn1c(SCC(=O)N2c3ccccc3Sc4ccccc24)nnc1c5cc(OC)cc(OC)c5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D01 compound treatment 1595582.0 -266000.0 -0.5 1425677.0 -302000.0 -0.6 -0.7796 -0.9957 3632297 CBKinase1_022385 CC(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccc(Oc3ccccc3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D02 compound treatment 1847788.0 -14000.0 -0.03 1711111.0 -16200.0 -0.03 -0.0414 -0.9949 3632298 CBKinase1_022386 COc1ccccc1NC(=O)C(C)NS(=O)(=O)c2ccc(F)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D03 compound treatment 1845540.0 -16300.0 -0.03 1953421.0 226000.0 0.45 0.298 0.6578 3632299 CBKinase1_022387 COc1ccc(NC(=O)C(=O)NCC(=O)Nc2ccccc2OC)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D04 compound treatment 1820142.0 -41700.0 -0.08 1809410.0 82100.0 0.16 0.0608 0.3342 3632300 CBKinase1_022388 COC(=O)c1cc(NC(=O)CSc2nnc(c3ccccc3O)n2c4ccccc4)ccc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D05 compound treatment 1944478.0 82700.0 0.16 1645635.0 -81600.0 -0.16 -0.0056 -0.025 3632301 CBKinase1_022389 Clc1ccccc1NC(=O)CSc2nc3cc4ccccc4cc3[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D06 compound treatment 1940569.0 78800.0 0.15 1689964.0 -37300.0 -0.07 0.0518 0.313 3632302 CBKinase1_022390 CC(=O)c1cccc(NC(=O)CSc2nnc(c3ccccc3Cl)n2c4ccccc4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D07 compound treatment 1975282.0 113000.0 0.21 1770986.0 43700.0 0.09 0.2124 0.9226 3632303 CBKinase1_022391 CCN(CC(=O)Nc1cccc(OC)c1)S(=O)(=O)c2ccc(C)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D08 compound treatment 851476.0 -1010000.0 -1.9 1008737.0 -719000.0 -1.44 -2.3567 -0.9906 3632304 CBKinase1_022392 CCOc1cc(C)c(Cl)cc1S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D09 compound treatment 2072870.0 211000.0 0.4 1789263.0 62000.0 0.12 0.3678 0.8859 3632305 CBKinase1_022393 CC(C)NS(=O)(=O)c1ccc(NC(=O)C2CCCCC2C(=O)O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D10 compound treatment 2319387.0 458000.0 0.86 1750183.0 22900.0 0.05 0.6398 0.7438 3632306 CBKinase1_022394 CC(Oc1cccc(Br)c1)C(=O)Nc2ccc(C)cc2[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D11 mock treatment 2137839.0 276000.0 0.52 1999597.0 272000.0 0.54 0.7513 0.9997 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D12 mock treatment 2226464.0 365000.0 0.68 1874797.0 148000.0 0.29 0.6926 0.9292 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D13 compound treatment 2150945.0 289000.0 0.54 1703086.0 -24200.0 -0.05 0.3496 0.6416 3632307 CBKinase1_022395 CC(C)NS(=O)(=O)c1ccc(OCC(=O)N)c(Cl)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D14 compound treatment 2119052.0 257000.0 0.48 1914592.0 187000.0 0.37 0.6062 0.9921 3632308 CBKinase1_022396 CC(=O)Nc1ccc(cc1)C(=O)Nc2ccc(OCC(=O)O)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D15 mock treatment 1968118.0 106000.0 0.2 1972412.0 245000.0 0.49 0.4876 0.9216 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D16 mock treatment 2099641.0 238000.0 0.45 1929251.0 202000.0 0.4 0.6012 0.9987 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D17 compound treatment 2002556.0 141000.0 0.26 1511722.0 -216000.0 -0.43 -0.1178 -0.2331 3632309 CBKinase1_022397 CC(C)c1ccc(cc1)N2C(=C(C(=O)C)C(NS(=O)(=O)c3ccc(NC(=O)C)cc3)(C2=O)C(F)(F)F)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D18 compound treatment 468388.0 -1390000.0 -2.62 352872.0 -1370000.0 -2.75 -3.7921 -0.9997 3632310 CBKinase1_022398 Oc1c(cc(Cl)c2cccnc12)C(Nc3ccccn3)c4ccccc4Br 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D19 compound treatment 2049176.0 187000.0 0.35 2160998.0 434000.0 0.87 0.8617 0.9211 3632311 CBKinase1_022399 COC(=O)c1sccc1NC(=O)CN2c3cccc4cccc(c34)S2(=O)=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D20 compound treatment 1543438.0 -318000.0 -0.6 1780890.0 53600.0 0.11 -0.3468 -0.5712 3632312 CBKinase1_022400 Cc1cc(OCC(=O)Nc2cccc(c2)C(=O)O)cc(C)c1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D21 compound treatment 1929262.0 67400.0 0.13 1639338.0 -87900.0 -0.18 -0.0347 -0.1603 3632313 CBKinase1_022401 CCn1c(SCC(=O)Nc2ccccc2Br)nnc1c3ccccc3O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D22 compound treatment 1865719.0 3910.0 0.01 1641288.0 -86000.0 -0.17 -0.1163 -0.6763 3632314 CBKinase1_022402 COc1cc(C(Nc2ccccn2)c3cc(Cl)c4cccnc4c3O)c(Br)cc1OC(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D23 compound treatment 1769658.0 -92200.0 -0.17 1495860.0 -231000.0 -0.46 -0.4494 -0.91 3632315 CBKinase1_022403 Ic1cccc(c1)C(=O)Nc2ccc(OCc3nc4ccccc4s3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 D24 compound treatment 1112731.0 -749000.0 -1.41 1625144.0 -102000.0 -0.2 -1.1387 -0.8013 1690364 CBKinase1_022404 COC(=O)c1ccc(C(=O)OC)c(NC(=O)COc2ccc(C)cc2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E01 mock treatment 1277920.0 -584000.0 -1.1 1402157.0 -325000.0 -0.65 -1.2346 -0.9688 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E02 mock treatment 1427074.0 -435000.0 -0.82 1556816.0 -170000.0 -0.34 -0.818 -0.9249 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E03 compound treatment 1842524.0 -19300.0 -0.04 1632625.0 -94600.0 -0.19 -0.1594 -0.8275 3632316 CBKinase1_022405 Cc1ccnn1CCCNC(=O)c2cc(nc3c(C)c(Cl)ccc23)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E04 compound treatment 1343492.0 -518000.0 -0.97 1293403.0 -434000.0 -0.87 -1.3012 -0.9983 3632317 CBKinase1_022406 COc1ccc(Cl)cc1N2CCN(CCNC(=O)Nc3ccccc3C)CC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E05 compound treatment 1631582.0 -230000.0 -0.43 1453142.0 -274000.0 -0.55 -0.693 -0.9931 3632318 CBKinase1_022407 COC(=O)CNC(=O)c1cc(nc2c(C)c(Cl)ccc12)c3ccncc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E06 compound treatment 1634581.0 -227000.0 -0.43 1456332.0 -271000.0 -0.54 -0.6845 -0.993 3632319 CBKinase1_022408 C(Nc1ncnc2c1sc3nc(N4CCOCC4)c5CCCc5c32)c6ccco6 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E07 compound treatment 1826046.0 -35800.0 -0.07 1622705.0 -105000.0 -0.21 -0.1952 -0.8895 3632320 CBKinase1_022409 Brc1ccc2nc(cc(C(=O)Nc3cccc(Cn4cccn4)c3)c2c1)c5ccncc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E08 compound treatment 1933353.0 71500.0 0.13 1540709.0 -187000.0 -0.37 -0.1687 -0.4256 3632321 CBKinase1_022410 COc1ccccc1n2nnnc2SCC(=O)Nc3cc(OC)c(OC)c(OC)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E09 mock treatment 1891135.0 29300.0 0.06 1598058.0 -129000.0 -0.26 -0.1437 -0.5442 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E10 mock treatment 1865019.0 3210.0 0.01 1673595.0 -53700.0 -0.11 -0.0716 -0.6664 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E11 compound treatment 1661784.0 -200000.0 -0.38 1588807.0 -138000.0 -0.28 -0.4612 -0.9887 3632322 CBKinase1_022411 COc1ccc(OC)c(c1)c2cc(C(=O)NCCc3ccccc3OC)c4ccccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E12 compound treatment 1893128.0 31300.0 0.06 1873289.0 146000.0 0.29 0.2479 0.8328 3632323 CBKinase1_022412 Cc1cccc(OCCCC(=O)Nc2sc3CCCCc3c2C(=O)N)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E13 compound treatment 2349559.0 488000.0 0.92 1829179.0 102000.0 0.2 0.7915 0.8438 3632324 CBKinase1_022413 CCOC(=O)Nc1ccc2n(C)c(CN3CCOCC3)nc2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E14 compound treatment 2111781.0 250000.0 0.47 1784761.0 57500.0 0.11 0.4131 0.855 3632325 CBKinase1_022414 COC(=O)c1ccccc1NC(=O)c2ccc(NC(=O)CSc3ccc(C)cc3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E15 compound treatment 1785951.0 -75900.0 -0.14 1587226.0 -140000.0 -0.28 -0.2986 -0.9509 3632326 CBKinase1_022415 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)NC2CCCCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E16 compound treatment 1843343.0 -18500.0 -0.03 1620997.0 -106000.0 -0.21 -0.1747 -0.8118 3042735 CBKinase1_022416 CN(Cc1nc2ccccc2n1C)S(=O)(=O)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E17 mock treatment 1812705.0 -49100.0 -0.09 1455814.0 -271000.0 -0.54 -0.4488 -0.8156 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E18 mock treatment 2023825.0 162000.0 0.3 1536194.0 -191000.0 -0.38 -0.055 -0.1126 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E19 compound treatment 1486419.0 -375000.0 -0.7 1547244.0 -180000.0 -0.36 -0.7527 -0.9513 3632327 CBKinase1_022417 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2ccccc2F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E20 compound treatment 1650402.0 -211000.0 -0.4 1661466.0 -65800.0 -0.13 -0.3736 -0.8936 3632328 CBKinase1_022418 CCOC(=O)c1c(NC(=O)Cn2cnc3sc(cc3c2=O)c4ccccc4)sc5CCCCc15 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E21 compound treatment 1690874.0 -171000.0 -0.32 1519993.0 -207000.0 -0.41 -0.5198 -0.992 3632329 CBKinase1_022419 Cc1cccc(NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E22 compound treatment 1662604.0 -199000.0 -0.37 1333729.0 -394000.0 -0.79 -0.8206 -0.9422 3632330 CBKinase1_022420 COC(=O)c1ccccc1NC(=O)C2CCCN(C2)S(=O)(=O)c3ccc(Br)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E23 compound treatment 1429906.0 -432000.0 -0.81 1439484.0 -288000.0 -0.58 -0.9801 -0.9859 3632331 CBKinase1_022421 CC(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccc3OCCOc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 E24 compound treatment 1052982.0 -809000.0 -1.52 1120782.0 -606000.0 -1.21 -1.9308 -0.9938 3632332 CBKinase1_022422 Clc1ccccc1NC(=O)CSc2nc(cc(=O)[nH]2)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F01 mock treatment 1656595.0 -205000.0 -0.39 1164329.0 -563000.0 -1.13 -1.068 -0.898 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F02 mock treatment 1655062.0 -207000.0 -0.39 1510402.0 -217000.0 -0.43 -0.5809 -0.9985 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F03 compound treatment 1909327.0 47500.0 0.09 1538211.0 -189000.0 -0.38 -0.2041 -0.5257 3632333 CBKinase1_022423 O=C(CSc1nnnn1C2CC3CCC2C3)Nc4ccnc5ccccc45 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F04 compound treatment 1660361.0 -201000.0 -0.38 1510058.0 -217000.0 -0.43 -0.5744 -0.9976 3632334 CBKinase1_022424 Cc1nn2c(CN(C(=O)c3ccco3)c4ccccc4)nnc2c5ccccc15 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F05 compound treatment 2026057.0 164000.0 0.31 1633996.0 -93300.0 -0.19 0.0862 0.2393 3632335 CBKinase1_022425 CCn1c(SCC(=O)Nc2ccc(cc2)[N+](=O)[O-])nnc1c3ccccc3F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F06 compound treatment 1919544.0 57700.0 0.11 1724731.0 -2530.0 -0.01 0.0731 0.6734 3632336 CBKinase1_022426 Cc1ccccc1NC(=O)CSc2nc(nc(n2)N3CCCCC3)N4CCCCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F07 compound treatment 2137436.0 276000.0 0.52 1752011.0 24700.0 0.05 0.4009 0.7712 3632337 CBKinase1_022427 CCN(CC(=O)Nc1ccc(OC)c(Cl)c1)S(=O)(=O)c2ccc3ccccc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F08 compound treatment 2161777.0 300000.0 0.56 1812193.0 84900.0 0.17 0.5182 0.8811 3632338 CBKinase1_022428 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2ccc(cc2)C(=O)N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F09 mock treatment 2157935.0 296000.0 0.56 1802589.0 75300.0 0.15 0.4996 0.8674 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F10 mock treatment 2483614.0 622000.0 1.17 1830510.0 103000.0 0.21 0.9713 0.8194 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F11 compound treatment 2286649.0 425000.0 0.8 1748788.0 21500.0 0.04 0.5944 0.7442 3632339 CBKinase1_022429 CC(Oc1ccc2c(C)cc(=O)oc2c1)C(=O)Nc3ccccc3[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F12 compound treatment 1821907.0 -39900.0 -0.07 1396036.0 -331000.0 -0.66 -0.5211 -0.7821 3632340 CBKinase1_022430 Cc1[nH]c2ccccc2c1C(=O)CSc3ccc4ccccc4n3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F13 compound treatment 2081302.0 219000.0 0.41 2006609.0 279000.0 0.56 0.6862 0.9888 3632341 CBKinase1_022431 COc1ccc(Cl)cc1NC(=O)CSc2nc3sccc3c(=O)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F14 compound treatment 2286537.0 425000.0 0.8 1766477.0 39200.0 0.08 0.6192 0.7729 3632342 CBKinase1_022432 O=C(CNC(=O)c1ccccc1)Nc2cccc(c2)c3cnc4ccccc4n3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F15 compound treatment 1504249.0 -358000.0 -0.67 1595808.0 -131000.0 -0.26 -0.6604 -0.9162 3632343 CBKinase1_022433 COc1ccc(Cl)cc1N2CCN(CCCNC(=S)Nc3ccc(Cl)cc3C)CC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F16 compound treatment 289887.0 -1570000.0 -2.95 287404.0 -1440000.0 -2.88 -4.1216 -0.9999 3632344 CBKinase1_022434 CSc1ccc(cc1)C(Nc2ccccn2)c3cc(Cl)c4cccnc4c3O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F17 mock treatment 2049519.0 188000.0 0.35 1888284.0 161000.0 0.32 0.4767 0.999 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F18 mock treatment 2379712.0 518000.0 0.97 1790013.0 62800.0 0.13 0.7762 0.7918 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F19 compound treatment 1933256.0 71400.0 0.13 1484363.0 -243000.0 -0.49 -0.2484 -0.4933 3632345 CBKinase1_022435 CN(C1CCCCC1)S(=O)(=O)c2ccc(NC(=O)C3CCCCC3C(=O)O)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F20 compound treatment 1510588.0 -351000.0 -0.66 1597270.0 -130000.0 -0.26 -0.65 -0.9171 3632346 CBKinase1_022436 COC(=O)c1ccccc1NC(=O)c2ccc(NC(=O)C(C)Oc3ccccc3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F21 compound treatment 1755585.0 -106000.0 -0.2 1512436.0 -215000.0 -0.43 -0.4446 -0.9392 3632347 CBKinase1_022437 [O-][N+](=O)c1cccc(CNc2nc3[nH]c4CCCc4c(=O)n3n2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F22 compound treatment 1778754.0 -83100.0 -0.16 1436216.0 -291000.0 -0.58 -0.5216 -0.8661 3632348 CBKinase1_022438 Clc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(Br)c3)[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F23 compound treatment 1524401.0 -337000.0 -0.63 1422039.0 -305000.0 -0.61 -0.8793 -0.9998 3632349 CBKinase1_022439 C(Oc1ccccc1)c2nc3ccccc3n2Cc4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 F24 compound treatment 1377858.0 -484000.0 -0.91 1268161.0 -459000.0 -0.92 -1.2913 -1.0 3632350 CBKinase1_022440 Cn1c(SCC(=O)Nc2cccc(Br)c2)nnc1c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G01 compound treatment 1507920.0 -354000.0 -0.66 1442285.0 -285000.0 -0.57 -0.8725 -0.9971 3632351 CBKinase1_022441 COC(=O)c1sccc1NC(=O)c2cc(nc3ccc(Br)cc23)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G02 compound treatment 1665070.0 -197000.0 -0.37 1883700.0 156000.0 0.31 -0.0401 -0.0828 3632352 CBKinase1_022442 CS(=O)(=O)N(CC(=O)Nc1ccc(Br)cc1)c2cc(Cl)c(Cl)cc2Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G03 mock treatment 1932349.0 70500.0 0.13 2027184.0 300000.0 0.6 0.5175 0.843 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G04 mock treatment 1939350.0 77500.0 0.15 2016379.0 289000.0 0.58 0.5115 0.8584 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G05 compound treatment 2272225.0 410000.0 0.77 2092710.0 365000.0 0.73 1.0613 0.9996 3632353 CBKinase1_022443 COC(=O)c1cc(OC)c(OC)cc1NC(=O)c2cc(nc3ccc(Cl)cc23)c4cccnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G06 compound treatment 2029525.0 168000.0 0.31 2087568.0 360000.0 0.72 0.7318 0.9312 3632354 CBKinase1_022444 Clc1ccccc1Oc2ccc(NC(=O)CN3C(=O)C4C(C5C=CC4C6CC65)C3=O)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G07 compound treatment 2249318.0 388000.0 0.73 1967905.0 241000.0 0.48 0.8545 0.9798 3632355 CBKinase1_022445 COc1ccc(cc1NC(=O)c2cc(nc3ccc(C)cc23)c4ccccn4)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G08 compound treatment 2467183.0 605000.0 1.14 2133594.0 406000.0 0.81 1.3779 0.9864 3632356 CBKinase1_022446 Cc1[nH]nc2OC(=C(C#N)C(c12)c3cc(C)cc(Cn4ccc(n4)C(F)(F)F)c3C)N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G09 compound treatment 2589984.0 728000.0 1.37 2119531.0 392000.0 0.78 1.521 0.9652 3632357 CBKinase1_022447 Cc1cnn(CCCNC(=O)c2cc(nc3ccc(Cl)cc23)c4cccnc4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G10 compound treatment 2305279.0 443000.0 0.83 2055657.0 328000.0 0.66 1.0528 0.9931 3632358 CBKinase1_022448 COc1ccccc1CNc2nc3nc(C)cc(C)n3n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G11 compound treatment 2491194.0 629000.0 1.18 2189098.0 462000.0 0.92 1.4882 0.9925 3632359 CBKinase1_022449 Cc1ccc2nc(cc(C(=O)NCc3cccnc3)c2c1)c4cccc(Br)c4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G12 compound treatment 2450832.0 589000.0 1.11 2042627.0 315000.0 0.63 1.2276 0.9645 3632360 CBKinase1_022450 COC(=O)CNc1nc(OC)nc(n1)N(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G13 compound treatment 2178550.0 317000.0 0.59 2126181.0 399000.0 0.8 0.9842 0.9896 3632361 CBKinase1_022451 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)NC2CCCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G14 compound treatment 1898261.0 36400.0 0.07 2017672.0 290000.0 0.58 0.4588 0.785 3632362 CBKinase1_022452 CCn1c(SCC(=O)c2ccccc2)nnc1c3cc4cc(Br)ccc4o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G15 compound treatment 2499402.0 638000.0 1.2 2026457.0 299000.0 0.6 1.2692 0.9486 3632363 CBKinase1_022453 COC(=O)c1ccccc1NC(=O)CSc2nc3cccnc3[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G16 compound treatment 2550203.0 688000.0 1.29 2111010.0 384000.0 0.77 1.4562 0.969 3632364 CBKinase1_022454 COc1ccc(cc1)c2nc(SCC(=O)Nc3ccc(Cl)cc3)[nH]c(=O)c2C#N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G17 compound treatment 2035749.0 174000.0 0.33 2117050.0 390000.0 0.78 0.7818 0.9255 3632365 CBKinase1_022455 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2ccc(Br)cc2F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G18 compound treatment 2437692.0 576000.0 1.08 1979458.0 252000.0 0.5 1.1209 0.9397 3632366 CBKinase1_022456 O=C(CSc1nc2sccc2c(=O)[nH]1)Nc3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G19 mock treatment 2308032.0 446000.0 0.84 1975511.0 248000.0 0.5 0.9432 0.9687 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G20 mock treatment 2155998.0 294000.0 0.55 2081265.0 354000.0 0.71 0.8908 0.9925 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G21 compound treatment 2076478.0 215000.0 0.4 2102300.0 375000.0 0.75 0.815 0.9576 3632367 CBKinase1_022457 COc1ccc(cc1)S(=O)(=O)N(CC(=O)O)c2ccc(F)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G22 compound treatment 1997367.0 136000.0 0.25 2054113.0 327000.0 0.65 0.6419 0.9155 3632368 CBKinase1_022458 Clc1cc(Cl)cc(NC(=O)Cn2cnc3scc(c4ccccc4)c3c2=O)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G23 compound treatment 1876319.0 14500.0 0.03 2026191.0 299000.0 0.6 0.4417 0.7386 3632369 CBKinase1_022459 COc1ccccc1NC(=O)COc2ccc(cc2)C(=O)Nc3cccc(c3)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 G24 compound treatment 1820262.0 -41600.0 -0.08 1628759.0 -98500.0 -0.2 -0.1944 -0.9179 3632370 CBKinase1_022460 COC(=O)Cc1c(C)[nH]c2nc(COc3ccccc3)nn2c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H01 compound treatment 1483577.0 -378000.0 -0.71 1687186.0 -40100.0 -0.08 -0.5587 -0.7819 3632371 CBKinase1_022461 O=C(NCc1cccnc1)c2cccnc2c3nc4ccccc4s3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H02 compound treatment 587467.0 -1270000.0 -2.39 580155.0 -1150000.0 -2.29 -3.3129 -0.9998 3632372 CBKinase1_022462 CCN(CC)CCNc1ncnc2c1sc3nc(N4CCCC4)c5COC(C)(C)Cc5c32 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H03 mock treatment 2098462.0 237000.0 0.44 1768388.0 41100.0 0.08 0.3723 0.824 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H04 mock treatment 2177879.0 316000.0 0.59 1929299.0 202000.0 0.4 0.7051 0.9824 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H05 compound treatment 2090589.0 229000.0 0.43 1938934.0 212000.0 0.42 0.6028 1.0 3632373 CBKinase1_022463 COc1cccc(OCc2nc(no2)c3ccc(cc3)[N+](=O)[O-])c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H06 compound treatment 2184202.0 322000.0 0.61 2091360.0 364000.0 0.73 0.9425 0.9958 3632374 CBKinase1_022464 COc1ccc(cc1)C(=O)NCC(=O)Nc2ccc(C)c(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H07 compound treatment 2345036.0 483000.0 0.91 2017836.0 291000.0 0.58 1.0521 0.9768 3632375 CBKinase1_022465 CC(=O)Nc1ccc(NC(=O)CC2N(C(=O)C)c3ccccc3NC2=O)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H08 compound treatment 1995554.0 134000.0 0.25 1700433.0 -26800.0 -0.05 0.1396 0.5438 3632376 CBKinase1_022466 COc1ccc(cc1)n2c(SCC(=O)N(c3ccccc3)c4ccccc4)nc5ccccc5c2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H09 compound treatment 2466315.0 605000.0 1.13 2123566.0 396000.0 0.79 1.3626 0.9845 3632377 CBKinase1_022467 Cc1c(NC(=O)CSc2nnc(o2)c3cccc(Cl)c3)c(=O)n(c4ccccc4)n1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H10 compound treatment 2473676.0 612000.0 1.15 2233010.0 506000.0 1.01 1.527 0.998 2066029 CBKinase1_022468 O=C(OCc1nc2ccccc2s1)c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H11 compound treatment 1455763.0 -406000.0 -0.76 1270690.0 -457000.0 -0.91 -1.1843 -0.996 3632378 CBKinase1_022469 O=c1n(CCCN2CCN(Cc3ccccc3)CC2)c(=S)[nH]c4ccccc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H12 compound treatment 2234354.0 373000.0 0.7 2142845.0 416000.0 0.83 1.0819 0.9963 3632379 CBKinase1_022470 CCN(CC(=O)Nc1cc(ccc1C)[N+](=O)[O-])S(=O)(=O)c2ccc(C)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H13 compound treatment 2538678.0 677000.0 1.27 2379435.0 652000.0 1.3 1.8202 0.9999 3632380 CBKinase1_022471 O=C(Cn1cnc2sc(cc2c1=O)c3ccccc3)Nc4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H14 compound treatment 2223487.0 362000.0 0.68 2127083.0 400000.0 0.8 1.0452 0.9967 3632381 CBKinase1_022472 COc1ccc(cc1)C(=O)CSc2nnc(c3ccccc3)n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H15 compound treatment 1886834.0 25000.0 0.05 2039816.0 313000.0 0.62 0.4749 0.7581 3632382 CBKinase1_022473 CCOC(=O)c1ccccc1NC(=O)C(C)Oc2ccc3c(C)cc(=O)oc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H16 compound treatment 2591359.0 730000.0 1.37 2278121.0 551000.0 1.1 1.747 0.9941 3632383 CBKinase1_022474 CC(=O)Nc1ccc(cc1)C(=O)Nc2cccc(NC(=O)c3ccco3)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H17 compound treatment 1662494.0 -199000.0 -0.37 1478004.0 -249000.0 -0.5 -0.6169 -0.99 3632384 CBKinase1_022475 CN1CCN(CC1)c2ccccc2NC(=O)COc3ccccc3[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H18 compound treatment 978272.0 -884000.0 -1.66 1495799.0 -231000.0 -0.46 -1.5 -0.8711 3632385 CBKinase1_022476 Oc1c(cc(Cl)c2cccnc12)C(Nc3ccccn3)c4cccnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H19 mock treatment 2049384.0 188000.0 0.35 1924808.0 198000.0 0.39 0.5282 0.9984 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H20 mock treatment 2190429.0 329000.0 0.62 1891909.0 165000.0 0.33 0.6689 0.9567 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H21 compound treatment 2031436.0 170000.0 0.32 2068084.0 341000.0 0.68 0.7068 0.94 3632386 CBKinase1_022477 CCN(CC(=O)Nc1ccc2OCCOc2c1)S(=O)(=O)c3ccc(C)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H22 compound treatment 2227600.0 366000.0 0.69 1943794.0 217000.0 0.43 0.7916 0.9752 3632387 CBKinase1_022478 CC(=O)Nc1ccccc1C(=O)OCc2cccc(c2)C(=O)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H23 compound treatment 2010613.0 149000.0 0.28 1939678.0 212000.0 0.42 0.4977 0.9794 3632388 CBKinase1_022479 CC(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccc(F)c(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 H24 compound treatment 1702370.0 -159000.0 -0.3 1982393.0 255000.0 0.51 0.1489 0.2518 3632389 CBKinase1_022480 O=C(Nc1ccc(cc1)C(=O)OCc2cccc(c2)C(=O)c3ccccc3)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I01 compound treatment 1583565.0 -278000.0 -0.52 1348952.0 -378000.0 -0.76 -0.904 -0.9837 3632390 CBKinase1_022481 COc1ccccc1CCNC(=O)c2cc(nc3ccccc23)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I02 compound treatment 1531472.0 -330000.0 -0.62 1504655.0 -223000.0 -0.44 -0.7531 -0.9867 3632391 CBKinase1_022482 CC(C)N(Cc1nc(no1)c2cccc(C)c2)S(=O)(=O)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I03 compound treatment 1703106.0 -159000.0 -0.3 1556364.0 -171000.0 -0.34 -0.4522 -0.9977 3632392 CBKinase1_022483 Cc1ccc2nc(cc(C(=O)Nc3sc4CCCCCCc4c3C(=O)N)c2c1)c5cccnc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I04 compound treatment 1592269.0 -270000.0 -0.51 1491072.0 -236000.0 -0.47 -0.6916 -0.9994 3632393 CBKinase1_022484 CC(C)c1ccc(C)cc1OCC(=O)Nc2ccccc2N3CCN(C)CC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I05 mock treatment 2150141.0 288000.0 0.54 1855029.0 128000.0 0.26 0.5633 0.9412 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I06 mock treatment 1847373.0 -14400.0 -0.03 1826469.0 99200.0 0.2 0.121 0.6048 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I07 compound treatment 2104410.0 243000.0 0.46 2036635.0 309000.0 0.62 0.7593 0.9887 3632394 CBKinase1_022485 CC(NC(=O)c1cc(nc2c(C)cc(C)cc12)c3cccnc3)c4cnn(C)c4C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I08 compound treatment 1792242.0 -69600.0 -0.13 1716612.0 -10600.0 -0.02 -0.1074 -0.8116 3632395 CBKinase1_022486 Clc1ccc(cc1S(=O)(=O)Nc2ccccc2)C(=O)NCC3CCCO3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I09 compound treatment 1956552.0 94700.0 0.18 1702490.0 -24800.0 -0.05 0.0908 0.4916 3632396 CBKinase1_022487 Cc1ccc2nc(cc(C(=O)Nc3sc-4c(CCc5ccccc45)c3C(=O)N)c2c1)c6ccccn6 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I10 compound treatment 2177809.0 316000.0 0.59 2033275.0 306000.0 0.61 0.852 0.9999 3632397 CBKinase1_022488 COc1ccc(Cl)cc1NC(=O)CSc2nc(nc(n2)N3CCCCC3)N4CCCCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I11 compound treatment 2156209.0 294000.0 0.55 1972893.0 246000.0 0.49 0.738 0.9983 3632398 CBKinase1_022489 COc1ccccc1CCNC(=O)c2cc(nc3ccc(Br)cc23)c4ccncc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I12 compound treatment 2312814.0 451000.0 0.85 1903048.0 176000.0 0.35 0.8471 0.9241 3632399 CBKinase1_022490 COc1ccc(OC)c(NC(=O)COc2ccc(cc2)C(=O)Nc3ccc(Cl)cc3)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I13 compound treatment 2327255.0 465000.0 0.87 2006291.0 279000.0 0.56 1.0122 0.9765 3632400 CBKinase1_022491 CCOC(=O)c1ccccc1NC(=O)CSc2nc3ccccc3[nH]2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I14 compound treatment 2143012.0 281000.0 0.53 2015901.0 289000.0 0.58 0.7812 0.999 3632401 CBKinase1_022492 COc1ccc(NC(=O)c2cccc(NC(=O)C3C4CC5OC(=O)C3C5C4)c2)c(OC)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I15 compound treatment 2121620.0 260000.0 0.49 1897509.0 170000.0 0.34 0.5855 0.9845 3632402 CBKinase1_022493 CCOc1ccc(C)cc1S(=O)(=O)Nc2cccnc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I16 compound treatment 2157087.0 295000.0 0.55 1966481.0 239000.0 0.48 0.7301 0.9973 3632403 CBKinase1_022494 NC(=O)CN1C(=O)C(O)(CC(=O)c2ccc(Cl)s2)c3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I17 compound treatment 2309301.0 447000.0 0.84 1903074.0 176000.0 0.35 0.8425 0.9252 3632404 CBKinase1_022495 COc1cc(ccc1F)S(=O)(=O)Nc2cccnc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I18 compound treatment 2265869.0 404000.0 0.76 1868466.0 141000.0 0.28 0.7359 0.9093 3632405 CBKinase1_022496 COc1ccc(OC)c(NC(=O)CNC(=O)c2cccs2)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I19 compound treatment 1687660.0 -174000.0 -0.33 1756973.0 29700.0 0.06 -0.1892 -0.5694 3632406 CBKinase1_022497 COc1ccc(NC(=O)CSc2nncc3ccccc23)c(c1)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I20 compound treatment 1985245.0 123000.0 0.23 2002418.0 275000.0 0.55 0.5527 0.9262 3632407 CBKinase1_022498 COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)NC2CCCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I21 mock treatment 1967636.0 106000.0 0.2 1780847.0 53600.0 0.11 0.2162 0.958 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I22 mock treatment 1847189.0 -14600.0 -0.03 1680283.0 -47000.0 -0.09 -0.0858 -0.8771 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I23 compound treatment 1736287.0 -126000.0 -0.24 1856599.0 129000.0 0.26 0.0162 0.0462 3632408 CBKinase1_022499 CCN(CC(=O)Nc1ccc(C)c(C)c1)S(=O)(=O)c2ccc(C)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 I24 compound treatment 1048091.0 -814000.0 -1.53 1430625.0 -297000.0 -0.59 -1.4994 -0.915 3632409 CBKinase1_022500 Cc1cc(NC(=O)C(=O)NCc2cccnc2)ccc1Br 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J01 compound treatment 1265111.0 -597000.0 -1.12 1016776.0 -710000.0 -1.42 -1.7962 -0.9931 1436593 CBKinase1_022501 Ic1ccc(NC(=O)CSc2nc3ccccc3o2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J02 compound treatment 1662065.0 -200000.0 -0.37 1501210.0 -226000.0 -0.45 -0.5846 -0.9957 3632410 CBKinase1_022502 Cc1cc(C)c(NC(=O)CSc2nncc3ccccc23)c(c1)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J03 compound treatment 1646706.0 -215000.0 -0.4 1572463.0 -155000.0 -0.31 -0.5043 -0.9913 3632411 CBKinase1_022503 COc1ccc(cc1Cl)S(=O)(=O)N(C)CC(=O)Nc2cccc(c2)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J04 compound treatment 1817792.0 -44000.0 -0.08 1573435.0 -154000.0 -0.31 -0.2758 -0.8664 3632412 CBKinase1_022504 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)Nc2ccccc2c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J05 mock treatment 1975258.0 113000.0 0.21 1727734.0 472.0 0.0 0.1513 0.7102 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J06 mock treatment 1957870.0 96100.0 0.18 1681105.0 -46200.0 -0.09 0.0623 0.3075 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J07 compound treatment 2184423.0 323000.0 0.61 1688636.0 -38600.0 -0.08 0.3737 0.612 3632413 CBKinase1_022505 CC(C)NC(=O)CN(c1ccc(Br)c(C)c1)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J08 compound treatment 2055027.0 193000.0 0.36 1721024.0 -6240.0 -0.01 0.2477 0.6824 3632414 CBKinase1_022506 COc1ccc2nc(O)c(CN(C)S(=O)(=O)c3ccc(C)cc3)cc2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J09 compound treatment 2142406.0 281000.0 0.53 1891643.0 164000.0 0.33 0.6048 0.9742 3632415 CBKinase1_022507 COC(=O)c1ccc(C)c(NC(=O)CN(c2cc(Cl)c(Cl)cc2Cl)S(=O)(=O)C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J10 compound treatment 1830925.0 -30900.0 -0.06 1576323.0 -151000.0 -0.3 -0.2543 -0.8279 3632416 CBKinase1_022508 CSc1nsc(SCC(=O)c2ccc(cc2)[N+](=O)[O-])n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J11 compound treatment 1971589.0 110000.0 0.21 1776944.0 49700.0 0.1 0.2159 0.944 3632417 CBKinase1_022509 Clc1ccc(cc1C(=O)NCCOc2cccc(Oc3ccccc3)c2)n4cnnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J12 compound treatment 2121563.0 260000.0 0.49 1881499.0 154000.0 0.31 0.5628 0.9755 3632418 CBKinase1_022510 CCN(CC(=O)Nc1ccccc1SC)S(=O)(=O)c2ccc3ccccc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J13 compound treatment 1810497.0 -51300.0 -0.1 1747468.0 20200.0 0.04 -0.0396 -0.3787 3632419 CBKinase1_022511 COc1ccc2n(C)c(C)c(/C=C/c3nc4ccccc4c(=O)n3CCCO)c2c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J14 compound treatment 2026004.0 164000.0 0.31 1707003.0 -20300.0 -0.04 0.1893 0.609 3632421 CBKinase1_022512 COc1cccc2cc(oc12)c3nnc(SCC(=O)Nc4cccc(Br)c4)n3C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J15 compound treatment 2054261.0 192000.0 0.36 2026165.0 299000.0 0.6 0.6779 0.971 3632422 CBKinase1_022513 CCOC(=O)c1ccccc1NC(=O)C(C)Oc2cccc(Br)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J16 compound treatment 1944913.0 83100.0 0.16 1785955.0 58700.0 0.12 0.1933 0.9901 3632423 CBKinase1_022514 Nc1ccc(cc1)C(=O)CC2(O)C(=O)Nc3ccc(F)cc32 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J17 compound treatment 2054210.0 192000.0 0.36 1712349.0 -14900.0 -0.03 0.2343 0.6466 3632424 CBKinase1_022515 OC1(CC(=O)c2ccncc2)C(=O)N(Cc3ccccc3)c4ccc(Br)cc41 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J18 compound treatment 1522227.0 -340000.0 -0.64 1724522.0 -2740.0 -0.01 -0.4547 -0.7132 3632425 CBKinase1_022516 COc1cccc2cc(oc12)c3nnc(SCC(=O)Nc4cccc(F)c4)n3C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J19 compound treatment 1607731.0 -254000.0 -0.48 1409741.0 -318000.0 -0.63 -0.786 -0.9901 3632426 CBKinase1_022517 CN1CCN(CC1)c2ccccc2NC(=O)COc3ccc(Br)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J20 compound treatment 358893.0 -1500000.0 -2.82 325103.0 -1400000.0 -2.8 -3.9767 -1.0 3632427 CBKinase1_022518 COc1ccc(I)cc1C(Nc2cc(C)ccn2)c3ccc4cccnc4c3O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J21 mock treatment 2008992.0 147000.0 0.28 1721208.0 -6050.0 -0.01 0.1868 0.6755 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J22 mock treatment 1949176.0 87400.0 0.16 1772625.0 45400.0 0.09 0.1801 0.9609 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J23 compound treatment 1745602.0 -116000.0 -0.22 1639614.0 -87600.0 -0.18 -0.2781 -0.9941 3632428 CBKinase1_022519 CCN(CC(=O)Nc1ccc(cc1)C(F)(F)F)S(=O)(=O)c2ccc3ccccc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 J24 compound treatment 1626936.0 -235000.0 -0.44 1227595.0 -500000.0 -1.0 -1.018 -0.9325 3632429 CBKinase1_022520 O=C(Nc1ccc(cc1)C(=O)NCc2ccco2)c3cccs3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K01 compound treatment 1549113.0 -313000.0 -0.59 911902.0 -815000.0 -1.63 -1.5674 -0.9049 3632430 CBKinase1_022521 COc1ccc(CCNC(=O)c2cc(nc3c(Cl)cccc23)c4cccnc4)cc1OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K02 compound treatment 1564175.0 -298000.0 -0.56 1510498.0 -217000.0 -0.43 -0.7015 -0.9921 3632431 CBKinase1_022522 COc1ccccc1NC(=O)c2ccc(CSc3nc4ccccc4o3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K03 compound treatment 1459513.0 -402000.0 -0.76 1687595.0 -39700.0 -0.08 -0.5901 -0.7771 3632432 CBKinase1_022523 CCCc1ccc(cc1)c2cc(C(=O)NCc3cnn(C)c3)c4ccccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K04 compound treatment 1785277.0 -76500.0 -0.14 1686371.0 -40900.0 -0.08 -0.1594 -0.9642 1868225 CBKinase1_022524 COc1ccc(OC)c(NC(=O)Cc2coc3cc(C)cc(C)c23)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K05 compound treatment 1607008.0 -255000.0 -0.48 1775106.0 47800.0 0.1 -0.2706 -0.5548 3632433 CBKinase1_022525 Cc1ccc2c(cc(nc2c1C)c3ccccn3)C(=O)Nc4sc5CCCCCc5c4C(=O)N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K06 compound treatment 1961422.0 99600.0 0.19 2028696.0 301000.0 0.6 0.5582 0.8849 3632434 CBKinase1_022526 Oc1ccccc1c2nnc(SCC(=O)Nc3ccccc3Cl)n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K07 mock treatment 1840558.0 -21300.0 -0.04 2037439.0 310000.0 0.62 0.4102 0.6602 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K08 mock treatment 2080877.0 219000.0 0.41 1722114.0 -5150.0 -0.01 0.2835 0.6892 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K09 compound treatment 811002.0 -1050000.0 -1.97 736321.0 -991000.0 -1.98 -2.7954 -1.0 3632435 CBKinase1_022527 CC(CN1CCCCC1)NC(=O)c2cc(nc3ccc(Cl)cc23)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K10 compound treatment 1729941.0 -132000.0 -0.25 1985468.0 258000.0 0.52 0.1899 0.3317 3632436 CBKinase1_022528 CS(=O)(=O)N(CC(=O)NC1CCCCC1)c2cc(Cl)c(Cl)cc2Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K11 compound treatment 2114705.0 253000.0 0.47 1807071.0 79800.0 0.16 0.4485 0.8955 3632437 CBKinase1_022529 CC(NC(=O)c1cc(nc2ccc(C)cc12)c3ccncc3)c4cnn(C)c4C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K12 compound treatment 1513436.0 -348000.0 -0.65 1571397.0 -156000.0 -0.31 -0.6827 -0.9425 3632438 CBKinase1_022530 CCOc1ccc(Br)cc1CNCc2cccnc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K13 compound treatment 2246303.0 384000.0 0.72 2030970.0 304000.0 0.61 0.9396 0.9963 3632439 CBKinase1_022531 COC(=O)c1c(NC(=O)c2ccc(C)c(c2)S(=O)(=O)Nc3ccccc3C)sc4CCCCc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K14 compound treatment 1949006.0 87200.0 0.16 1864042.0 137000.0 0.27 0.3091 0.9699 3632440 CBKinase1_022532 Cc1cc(ccc1[N+](=O)[O-])C(=O)Nc2ccc(OCC(=O)O)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K15 mock treatment 1753604.0 -108000.0 -0.2 1829944.0 103000.0 0.21 0.0015 0.0051 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K16 mock treatment 2092842.0 231000.0 0.43 1980749.0 253000.0 0.51 0.6649 0.997 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K17 compound treatment 1881767.0 20000.0 0.04 1885142.0 158000.0 0.32 0.2496 0.7855 3632441 CBKinase1_022533 NC(=O)CN1C(=O)C(O)(CC(=O)c2ccncc2)c3ccccc13 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K18 compound treatment 1911903.0 50100.0 0.09 1905374.0 178000.0 0.36 0.3182 0.8642 3632442 CBKinase1_022534 Fc1ccc(NC(=O)CNC(=O)c2ccco2)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K19 compound treatment 1460238.0 -402000.0 -0.75 1588493.0 -139000.0 -0.28 -0.7292 -0.9078 3632443 CBKinase1_022535 OC(=O)C1CCCCC1C(=O)Nc2ccc(C#N)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K20 compound treatment 1456057.0 -406000.0 -0.76 1667190.0 -60100.0 -0.12 -0.6235 -0.8086 3632444 CBKinase1_022536 CC(N(c1ccc(C)cc1)S(=O)(=O)C)C(=O)NC2CCCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K21 compound treatment 2066365.0 205000.0 0.38 1816424.0 89200.0 0.18 0.3976 0.9391 3632445 CBKinase1_022537 CCN(CC(=O)Nc1ccc(Br)cc1F)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K22 compound treatment 1813995.0 -47800.0 -0.09 1692389.0 -34900.0 -0.07 -0.1128 -0.9922 3632446 CBKinase1_022538 Cn1c(=O)n(C)c2nc(SCc3nnn[nH]3)n(Cc4ccccc4F)c2c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K23 mock treatment 1558251.0 -304000.0 -0.57 1569835.0 -157000.0 -0.31 -0.6255 -0.9608 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 K24 mock treatment 1338800.0 -523000.0 -0.98 1398423.0 -329000.0 -0.66 -1.159 -0.9809 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L01 compound treatment 1417956.0 -444000.0 -0.83 1238582.0 -489000.0 -0.98 -1.2799 -0.9969 3632447 CBKinase1_022539 CCOc1ccc(C)cc1S(=O)(=O)NCC2CCCO2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L02 compound treatment 1733975.0 -128000.0 -0.24 1491007.0 -236000.0 -0.47 -0.5036 -0.9507 3632448 CBKinase1_022540 CCN(CC(=O)Nc1ccc(Br)cc1)S(=O)(=O)c2ccc(C)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L03 compound treatment 1567734.0 -294000.0 -0.55 1474899.0 -252000.0 -0.5 -0.747 -0.999 3632449 CBKinase1_022541 CC(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2ccccc2Sc3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L04 compound treatment 1862932.0 1120.0 0.0 1575581.0 -152000.0 -0.3 -0.2129 -0.7022 3632450 CBKinase1_022542 COC(=O)c1c(NC(=O)CCN2C(=O)c3ccccc3C2=O)sc(C)c1c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L05 compound treatment 1648466.0 -213000.0 -0.4 1619206.0 -108000.0 -0.22 -0.4359 -0.958 3632451 CBKinase1_022543 OC(CN1C(=O)c2ccccc2S1(=O)=O)Cn3ccc4ccccc34 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L06 compound treatment 1642868.0 -219000.0 -0.41 1424099.0 -303000.0 -0.61 -0.7191 -0.9821 3632452 CBKinase1_022544 COc1ccc(cc1[N+](=O)[O-])C(=O)CC2(O)C(=O)N(Cc3ccccc3)c4ccc(Br)cc42 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L07 mock treatment 1830816.0 -31000.0 -0.06 1747592.0 20300.0 0.04 -0.0124 -0.1749 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L08 mock treatment 1744589.0 -117000.0 -0.22 1780359.0 53100.0 0.11 -0.0806 -0.3298 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L09 compound treatment 1927626.0 65800.0 0.12 1719846.0 -7420.0 -0.01 0.0769 0.6179 3632453 CBKinase1_022545 Cc1ccccc1NC(=O)CSc2nc(cc(n2)C(F)(F)F)c3ccc(Cl)cc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L10 compound treatment 2082348.0 221000.0 0.41 1925021.0 198000.0 0.4 0.5722 0.9997 3632454 CBKinase1_022546 CCN(CC)c1nc(Oc2ccc(O)nn2)nc(n1)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L11 compound treatment 1917334.0 55500.0 0.1 1608551.0 -119000.0 -0.24 -0.0941 -0.363 3632455 CBKinase1_022547 CS(=O)(=O)N(CC(=O)Nc1cccc(c1)[N+](=O)[O-])c2ccc(F)c(Cl)c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L12 compound treatment 1926815.0 65000.0 0.12 2077127.0 350000.0 0.7 0.5807 0.8181 1164481 CBKinase1_022548 CCOC(=O)c1c(NC(=O)CN2C(=O)c3ccccc3C2=O)sc4CC(C)CCc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L13 compound treatment 1940949.0 79100.0 0.15 1760271.0 33000.0 0.07 0.1517 0.9332 3632456 CBKinase1_022549 CCOC(=O)c1sc2ncn(CC(=O)Nc3cccc(Br)c3)c(=O)c2c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L14 compound treatment 2066123.0 204000.0 0.38 1622937.0 -104000.0 -0.21 0.1238 0.2835 3632457 CBKinase1_022550 OC(=O)CNS(=O)(=O)c1ccc(cc1)C(=O)Nc2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L15 mock treatment 1769713.0 -92100.0 -0.17 1642507.0 -84800.0 -0.17 -0.242 -0.9999 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L16 mock treatment 1587502.0 -274000.0 -0.51 1870467.0 143000.0 0.29 -0.1618 -0.2745 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L17 compound treatment 1730685.0 -131000.0 -0.25 1967896.0 241000.0 0.48 0.166 0.3073 3632458 CBKinase1_022551 CC(=O)c1cccc(c1)N(CC(=O)Nc2ccc(C)cc2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L18 compound treatment 1942267.0 80500.0 0.15 1689862.0 -37400.0 -0.07 0.0539 0.3201 3632459 CBKinase1_022552 COC(=O)c1cc(NC(=O)COc2ccccc2Cl)cc(c1)C(=O)OC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L19 compound treatment 1628539.0 -233000.0 -0.44 1699894.0 -27400.0 -0.05 -0.3483 -0.7893 3632460 CBKinase1_022553 CCS(=O)(=O)c1nc2ccccc2n1CC(=O)N3CCCCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L20 compound treatment 1938421.0 76600.0 0.14 1749423.0 22200.0 0.04 0.133 0.8839 3632461 CBKinase1_022554 O=C(Nc1ccc(cc1)C(=O)NCc2ccccn2)c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L21 compound treatment 1661880.0 -200000.0 -0.38 2371215.0 644000.0 1.29 0.6447 0.4809 3632462 CBKinase1_022555 Cc1ccc(cc1)S(=O)(=O)NC(=O)N(CCC#N)c2ccccc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L22 compound treatment 1692870.0 -169000.0 -0.32 1599351.0 -128000.0 -0.26 -0.405 -0.9943 3632463 CBKinase1_022556 Cc1cccc(c1)c2nnc(SCC(=O)c3ccccc3)n2c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L23 mock treatment 1498224.0 -364000.0 -0.68 1448888.0 -278000.0 -0.56 -0.8761 -0.9949 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 L24 mock treatment 1452013.0 -410000.0 -0.77 1331819.0 -395000.0 -0.79 -1.1029 -0.9999 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M01 compound treatment 1466979.0 -395000.0 -0.74 1289384.0 -438000.0 -0.88 -1.143 -0.9966 3632464 CBKinase1_022557 Cc1ccccc1c2cc(C(=O)NCCCN3CCOCC3)c4cc(Cl)ccc4n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M02 compound treatment 1580269.0 -282000.0 -0.53 1526970.0 -200000.0 -0.4 -0.6568 -0.9906 3632465 CBKinase1_022558 O=C(Nc1cccc(c1)C(=O)OC2Cc3ccccc3C2=O)c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M03 compound treatment 1423021.0 -439000.0 -0.82 1409483.0 -318000.0 -0.64 -1.0316 -0.9917 3632466 CBKinase1_022559 CCc1cc(C(=O)OC)c(NC(=O)c2cc(nc3ccc(Br)cc23)c4cccnc4)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M04 compound treatment 1448907.0 -413000.0 -0.78 1384950.0 -342000.0 -0.68 -1.0319 -0.9981 3632467 CBKinase1_022560 COc1ccc(C)cc1S(=O)(=O)N2CCC(CC2)C(=O)Nc3cccc(c3)C(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M05 compound treatment 1516369.0 -345000.0 -0.65 1694412.0 -32800.0 -0.07 -0.505 -0.7747 3632468 CBKinase1_022561 CN(C)C(=O)c1sc(NC(=O)c2cc(nc3c(C)c(Cl)ccc23)c4cccnc4)c(C#N)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M06 compound treatment 1465829.0 -396000.0 -0.74 1552495.0 -175000.0 -0.35 -0.7727 -0.9407 3632469 CBKinase1_022562 Cc1cc(Cn2ccc(n2)C(F)(F)F)c(C)c(c1)c3c(C#N)c(N)nc4CCCCCc34 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M07 compound treatment 1872646.0 10800.0 0.02 1618027.0 -109000.0 -0.22 -0.14 -0.6385 3632470 CBKinase1_022563 COC(=O)CNC(=O)c1cc(nc2ccc(C)cc12)c3ccncc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M08 compound treatment 1924414.0 62600.0 0.12 1763611.0 36300.0 0.07 0.1345 0.9733 3632471 CBKinase1_022564 [O-][N+](=O)c1ccc(cc1)C(=O)NCC(=O)Nc2cccc(c2)C(F)(F)F 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M09 mock treatment 1935502.0 73700.0 0.14 1671025.0 -56200.0 -0.11 0.0183 0.1029 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M10 mock treatment 1857364.0 -4450.0 -0.01 1741510.0 14200.0 0.03 0.0142 0.4795 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M11 compound treatment 1879737.0 17900.0 0.03 1660118.0 -67100.0 -0.13 -0.0711 -0.5139 3632472 CBKinase1_022565 Cc1cc(C)c2nc(cc(C(=O)NCCc3ccc(cc3)S(=O)(=O)N)c2c1)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M12 compound treatment 1784527.0 -77300.0 -0.15 1783220.0 56000.0 0.11 -0.0235 -0.1283 3632473 CBKinase1_022566 CCN(CC(=O)Nc1ccc(Br)cc1)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M13 mock treatment 1861362.0 -451.0 0.0 1610154.0 -117000.0 -0.23 -0.1661 -0.7097 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M14 mock treatment 1875553.0 13700.0 0.03 1610132.0 -117000.0 -0.23 -0.1473 -0.6254 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M15 compound treatment 1854840.0 -6970.0 -0.01 1633123.0 -94100.0 -0.19 -0.1423 -0.7545 3632474 CBKinase1_022567 COc1ccc(cc1NC(=O)COc2cccc(C)c2)c3nc4ccccc4s3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M16 compound treatment 1671152.0 -191000.0 -0.36 1238280.0 -489000.0 -0.98 -0.9442 -0.9072 3632475 CBKinase1_022568 Cc1[nH]c2ccccc2c1C(=O)CSc3nnc4ccccn34 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M17 compound treatment 1781265.0 -80500.0 -0.15 1667831.0 -59400.0 -0.12 -0.1909 -0.9929 3632476 CBKinase1_022569 Cc1cc(ccc1NC(=O)CCCC(=O)O)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M18 compound treatment 1719382.0 -142000.0 -0.27 1377143.0 -350000.0 -0.7 -0.6839 -0.9129 3632477 CBKinase1_022570 Cc1cccc(NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M19 compound treatment 1667372.0 -194000.0 -0.37 1449013.0 -278000.0 -0.56 -0.6514 -0.9792 3632478 CBKinase1_022571 CSc1nsc(SCC(=O)Nc2ccc(C)c(Cl)c2)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M20 compound treatment 1868021.0 6210.0 0.01 1634950.0 -92300.0 -0.18 -0.1222 -0.6611 3632479 CBKinase1_022572 Cc1ccc(c(C)c1)S(=O)(=O)NC(=O)COc2cccc3ccccc23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M21 compound treatment 1666976.0 -195000.0 -0.37 1472336.0 -255000.0 -0.51 -0.6189 -0.9868 1868350 CBKinase1_022573 COC(=O)c1ccccc1NC(=O)Cc2coc3cc(C)cc(C)c23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M22 compound treatment 1422372.0 -439000.0 -0.82 1466589.0 -261000.0 -0.52 -0.9518 -0.9754 3632480 CBKinase1_022574 Cc1cc(ccc1OCC(=O)O)S(=O)(=O)NC2CCCCC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M23 compound treatment 1361125.0 -501000.0 -0.94 1459298.0 -268000.0 -0.54 -1.0434 -0.9644 3632481 CBKinase1_022575 COc1cc(OC)cc(c1)C(=O)N(Cc2nc(no2)c3cccc(C)c3)C(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 M24 compound treatment 1595261.0 -267000.0 -0.5 1500741.0 -227000.0 -0.45 -0.674 -0.9988 3632482 CBKinase1_022576 COc1ccc(cc1NC(=S)NC(=O)COc2ccc(C)cc2)c3nc4ccccc4s3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N01 compound treatment 1124081.0 -738000.0 -1.38 1331823.0 -395000.0 -0.79 -1.5382 -0.9646 3632483 CBKinase1_022577 CCOC(=O)c1c(NC(=O)c2sc3nc(C)cc(COC)c3c2N)sc4CCCCc14 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N02 compound treatment 1606837.0 -255000.0 -0.48 1355887.0 -371000.0 -0.74 -0.8633 -0.9775 3632484 CBKinase1_022578 COc1ccc(OC)c(c1)S(=O)(=O)N2CCC(CC2)C(=O)Nc3ccccc3SC 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N03 compound treatment 1401671.0 -460000.0 -0.86 1553061.0 -174000.0 -0.35 -0.857 -0.9202 3632485 CBKinase1_022579 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)NC2CC2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N04 compound treatment 1717804.0 -144000.0 -0.27 1576477.0 -151000.0 -0.3 -0.4043 -0.9985 3632486 CBKinase1_022580 N#Cc1ccccc1CSc2nc(nc(n2)N3CCCCC3)N4CCCCC4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N05 compound treatment 1825894.0 -35900.0 -0.07 1501120.0 -226000.0 -0.45 -0.3673 -0.8037 3632487 CBKinase1_022581 COc1ccc(cc1C)S(=O)(=O)N(C)CC(=O)Nc2ccc3OCCOc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N06 compound treatment 1630090.0 -232000.0 -0.44 1662219.0 -65000.0 -0.13 -0.3995 -0.88 3632488 CBKinase1_022582 CS(=O)(=O)N(CC(=O)N)c1ccc(F)c(Cl)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N07 compound treatment 1855857.0 -5960.0 -0.01 1781507.0 54200.0 0.11 0.0688 0.6308 3632489 CBKinase1_022583 COc1ccc(Cl)cc1Nc2nc(N)nc(n2)c3cc4ccccc4o3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N08 compound treatment 1723421.0 -138000.0 -0.26 1573347.0 -154000.0 -0.31 -0.4012 -0.9965 3632490 CBKinase1_022584 CC(C)Nc1nc(SCC(=O)Nc2ccccc2)nc(n1)N3CCOCC3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N09 mock treatment 1864882.0 3070.0 0.01 1930303.0 203000.0 0.41 0.291 0.7171 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N10 mock treatment 1932118.0 70300.0 0.13 1839302.0 112000.0 0.22 0.2517 0.9682 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N11 compound treatment 1926280.0 64500.0 0.12 1687185.0 -40100.0 -0.08 0.0289 0.1994 1868351 CBKinase1_022585 COC(=O)c1ccccc1NC(=O)Cc2coc3c(C)c(C)ccc23 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N12 compound treatment 1900547.0 38700.0 0.07 1819727.0 92500.0 0.18 0.1821 0.9169 3632491 CBKinase1_022586 FC(F)(F)c1cc(nc(SCCC(=O)Nc2ccccc2)c1C#N)c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N13 mock treatment 1692234.0 -170000.0 -0.32 1801846.0 74600.0 0.15 -0.1197 -0.3405 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N14 mock treatment 1792897.0 -68900.0 -0.13 1709755.0 -17500.0 -0.03 -0.1162 -0.8672 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N15 compound treatment 1898644.0 36800.0 0.07 1809916.0 82700.0 0.17 0.1657 0.9253 3632492 CBKinase1_022587 COC(=O)Cc1c(C)[nH]c2nc(nn2c1=O)c3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N16 compound treatment 357573.0 -1500000.0 -2.82 375218.0 -1350000.0 -2.7 -3.9077 -0.9998 3632493 CBKinase1_022588 Oc1c(cc(Cl)c2cccnc12)C(Nc3ccccn3)c4ccccc4[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N17 compound treatment 1711622.0 -150000.0 -0.28 1760070.0 32800.0 0.07 -0.153 -0.5286 3632494 CBKinase1_022589 CCOC(=O)c1ccc(NC(=O)CSc2nc(C)cc(n2)C(F)(F)F)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N18 compound treatment 1788172.0 -73600.0 -0.14 1791989.0 64700.0 0.13 -0.0063 -0.0332 3632495 CBKinase1_022590 O=C(Nc1ccccc1)c2ccc(cc2)S(=O)(=O)NCc3ccco3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N19 compound treatment 1160193.0 -702000.0 -1.32 1160975.0 -566000.0 -1.13 -1.7317 -0.9971 3632496 CBKinase1_022591 COc1ccc2ccccc2c1CNCc3ccccn3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N20 compound treatment 1652756.0 -209000.0 -0.39 1428492.0 -299000.0 -0.6 -0.6998 -0.9793 3632497 CBKinase1_022592 COC(=O)c1ccccc1NC(=O)COc2ccc(I)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N21 compound treatment 1752126.0 -110000.0 -0.21 1674106.0 -53200.0 -0.11 -0.2207 -0.9526 3632498 CBKinase1_022593 CCOC(=O)c1c(C)c(sc1NC(=O)CN2CCOCC2)C(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N22 compound treatment 1648595.0 -213000.0 -0.4 1520121.0 -207000.0 -0.41 -0.5758 -0.9999 3632499 CBKinase1_022594 Fc1cccc(NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N23 compound treatment 1386786.0 -475000.0 -0.89 1548817.0 -178000.0 -0.36 -0.8828 -0.9191 3632500 CBKinase1_022595 CC(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc2cc(Cl)ccc2Oc3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 N24 compound treatment 1489662.0 -372000.0 -0.7 1273472.0 -454000.0 -0.91 -1.1354 -0.9917 3632501 CBKinase1_022596 O=C(Nc1ccccc1C(=O)OCc2ccc(cc2)C(=O)c3ccccc3)c4ccco4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O01 compound treatment 1114995.0 -747000.0 -1.4 1137683.0 -590000.0 -1.18 -1.8246 -0.9963 3632502 CBKinase1_022597 Cc1cc(C)c2nc(cc(C(=O)NCCCn3ccnc3)c2c1)c4ccncc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O02 compound treatment 1255061.0 -607000.0 -1.14 1306457.0 -421000.0 -0.84 -1.4002 -0.9889 3632503 CBKinase1_022598 Cc1ccc(OCCSc2nnc3[nH]c4ccccc4n23)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O03 compound treatment 1281659.0 -580000.0 -1.09 1372394.0 -355000.0 -0.71 -1.2717 -0.9784 3632504 CBKinase1_022599 CC(=O)Nc1cccc(NC(=O)c2cc(nc3ccc(Cl)cc23)c4ccccn4)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O04 compound treatment 1405037.0 -457000.0 -0.86 1553580.0 -174000.0 -0.35 -0.8518 -0.9208 3632505 CBKinase1_022600 Nc1cc(O)nc(SCC(=O)N2CCN(CC2)c3ccccc3)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O05 compound treatment 1536672.0 -325000.0 -0.61 1296003.0 -431000.0 -0.86 -1.0411 -0.9857 3632506 CBKinase1_022601 CCc1cc(C(=O)OC)c(NC(=O)c2cc(nc3ccc(Cl)cc23)c4ccccn4)s1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O06 compound treatment 1567992.0 -294000.0 -0.55 1560872.0 -166000.0 -0.33 -0.6252 -0.9707 3632507 CBKinase1_022602 CCOc1ccccc1CNc2nc3[nH]c4CCCc4c(=O)n3n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O07 compound treatment 1531413.0 -330000.0 -0.62 1455353.0 -272000.0 -0.54 -0.8229 -0.9978 3632508 CBKinase1_022603 Cc1ccc2nc(cc(C(=O)Nc3ccc(CC(=O)O)cc3)c2c1)c4cccnc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O08 compound treatment 1063930.0 -798000.0 -1.5 1197136.0 -530000.0 -1.06 -1.8084 -0.9856 3632509 CBKinase1_022604 CC1(C)Cc2c(CO1)sc3c2c(=O)n(c4cccc(Cl)c4)c5nnc(SCC(=O)Nc6cccc(Cl)c6)n53 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O09 compound treatment 1683104.0 -179000.0 -0.34 1574510.0 -153000.0 -0.31 -0.4531 -0.9989 3632510 CBKinase1_022605 COc1ccccc1CCNC(=O)c2cc(nc3ccc(Br)cc23)c4ccccn4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O10 compound treatment 1435654.0 -426000.0 -0.8 1326526.0 -401000.0 -0.8 -1.1321 -1.0 3632511 CBKinase1_022606 CS(=O)(=O)N(CC(=O)Nc1ccccc1C(=O)N2CCOCC2)c3ccc(F)c(Cl)c3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O11 mock treatment 1446152.0 -416000.0 -0.78 1481264.0 -246000.0 -0.49 -0.8994 -0.9752 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O12 mock treatment 1413292.0 -449000.0 -0.84 1381067.0 -346000.0 -0.69 -1.0847 -0.9952 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O13 compound treatment 1344765.0 -517000.0 -0.97 1443883.0 -283000.0 -0.57 -1.0869 -0.9671 3632512 CBKinase1_022607 COc1ccc(OCC(=O)Nc2cc(Cl)ccc2N3CCOCC3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O14 compound treatment 1369248.0 -493000.0 -0.92 1502172.0 -225000.0 -0.45 -0.972 -0.9452 3632513 CBKinase1_022608 CCN(CC(=O)Nc1cc(ccc1Cl)C(F)(F)F)S(=O)(=O)c2ccc(Cl)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O15 compound treatment 1452084.0 -410000.0 -0.77 1259401.0 -468000.0 -0.94 -1.2051 -0.9953 3632514 CBKinase1_022609 CCN(CC(=O)Nc1ccccc1OC)S(=O)(=O)c2ccc(C)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O16 compound treatment 1689574.0 -172000.0 -0.32 1497935.0 -229000.0 -0.46 -0.5527 -0.9854 3632515 CBKinase1_022610 COC(=O)c1cc(NC(=O)CN(c2ccc(F)c(Cl)c2)S(=O)(=O)C)ccc1Cl 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O17 compound treatment 1558239.0 -304000.0 -0.57 1625780.0 -101000.0 -0.2 -0.5464 -0.9033 3632516 CBKinase1_022611 Nc1n[nH]c(SCC(=O)N2CCc3ccccc23)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O18 compound treatment 1393398.0 -468000.0 -0.88 1370469.0 -357000.0 -0.71 -1.1261 -0.9946 3632517 CBKinase1_022612 Cc1cccc(NC(=O)CN(c2ccc(Br)c(C)c2)S(=O)(=O)C)c1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O19 compound treatment 1405616.0 -456000.0 -0.86 1487866.0 -239000.0 -0.48 -0.9439 -0.9622 3632518 CBKinase1_022613 COC(=O)Cc1c(C)[nH]c2nc(NCc3ccccc3)nn2c1=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O20 compound treatment 1222045.0 -640000.0 -1.2 1351481.0 -376000.0 -0.75 -1.3804 -0.9744 3632519 CBKinase1_022614 CCOc1cc(ccc1F)S(=O)(=O)NCc2ccco2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O21 compound treatment 1059824.0 -802000.0 -1.51 1030518.0 -697000.0 -1.39 -2.0493 -0.9992 3632520 CBKinase1_022615 Fc1ccc(NC(=O)CSc2nnc([nH]2)c3ccccc3)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O22 compound treatment 1681294.0 -181000.0 -0.34 1581146.0 -146000.0 -0.29 -0.4461 -0.9973 3632521 CBKinase1_022616 NC(=O)CSc1nnc(c2ccccc2O)n1c3ccccc3 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O23 compound treatment 1523824.0 -338000.0 -0.63 1377382.0 -350000.0 -0.7 -0.9432 -0.9988 3632522 CBKinase1_022617 COc1ccc(Cl)cc1NC(=O)CSc2nc(N)cc(O)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 O24 compound treatment 1223226.0 -639000.0 -1.2 1165863.0 -561000.0 -1.12 -1.6411 -0.9995 3632523 CBKinase1_022618 OC(=O)CCc1nc2c3c4CCCCc4sc3ncn2n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P01 compound treatment 868450.0 -993000.0 -1.86 836591.0 -891000.0 -1.78 -2.5774 -0.9997 3632524 CBKinase1_022619 O=C(CSc1nnc(c2ccncc2)n1c3ccccc3)Nc4ccnc5ccccc45 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P02 compound treatment 1058440.0 -803000.0 -1.51 1015011.0 -712000.0 -1.42 -2.0731 -0.9996 3632525 CBKinase1_022620 CC(N(c1ccc(Cl)cc1)S(=O)(=O)C)C(=O)Nc2cc(C)ccc2C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P03 compound treatment 1022028.0 -840000.0 -1.58 1016563.0 -711000.0 -1.42 -2.1192 -0.9986 3632526 CBKinase1_022621 Cc1cccc(NC(=O)c2ccc(OCC(=O)Nc3ccc(Cl)c(Cl)c3)cc2)c1C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P04 compound treatment 1066154.0 -796000.0 -1.49 1125273.0 -602000.0 -1.2 -1.907 -0.9942 3632527 CBKinase1_022622 COc1ccc(cc1)c2cc(C)nc(SCC(=O)N3c4ccccc4Sc5ccccc35)n2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P05 compound treatment 1317752.0 -544000.0 -1.02 937235.0 -790000.0 -1.58 -1.8388 -0.9778 3632528 CBKinase1_022623 OC(=O)CCCC(=O)Nc1cc(ccc1Cl)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P06 compound treatment 1213941.0 -648000.0 -1.22 1105189.0 -622000.0 -1.24 -1.7392 -0.9999 3632529 CBKinase1_022624 Cc1[nH]c2ccccc2c1C(=O)CSc3nc4sc(C)c(C)c4c(=O)n3c5ccccc5 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P07 compound treatment 1309219.0 -553000.0 -1.04 1191138.0 -536000.0 -1.07 -1.4913 -0.9999 3632530 CBKinase1_022625 Cc1cc(ccc1Br)N(CC(=O)NC2CC2)S(=O)(=O)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P08 compound treatment 1310786.0 -551000.0 -1.03 1128745.0 -599000.0 -1.2 -1.5774 -0.9974 3632531 CBKinase1_022626 COc1ccc(C)cc1S(=O)(=O)N2CCCC(C2)C(=O)N 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P09 compound treatment 1226001.0 -636000.0 -1.19 1320101.0 -407000.0 -0.81 -1.4195 -0.9826 3632532 CBKinase1_022627 COc1ccccc1n2c(SCC(=O)N3CCOCC3)nc4ccccc4c2=O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P10 compound treatment 1355435.0 -506000.0 -0.95 1069888.0 -657000.0 -1.31 -1.6013 -0.9874 3632533 CBKinase1_022628 COc1ccc(cc1)C(=O)N(Cc2nc(no2)c3ccc(C)cc3)C(C)C 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P11 mock treatment 1132039.0 -730000.0 -1.37 1335740.0 -392000.0 -0.78 -1.5221 -0.9647 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P12 mock treatment 1765121.0 -96700.0 -0.18 1320272.0 -407000.0 -0.81 -0.7035 -0.8441 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P13 compound treatment 1123305.0 -739000.0 -1.39 1170313.0 -557000.0 -1.11 -1.7675 -0.9941 3632534 CBKinase1_022629 Cc1sc2ncn(CC(=O)Nc3cc(ccc3Cl)C(F)(F)F)c(=O)c2c1c4ccccc4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P14 compound treatment 1150508.0 -711000.0 -1.34 1315942.0 -411000.0 -0.82 -1.5256 -0.9728 3632535 CBKinase1_022630 OC(=O)c1ccc(cc1)C(Nc2ccccn2)c3cc(Cl)c4cccnc4c3O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P15 compound treatment 1559817.0 -302000.0 -0.57 1217897.0 -509000.0 -1.02 -1.1208 -0.9618 3632536 CBKinase1_022631 Cc1cc(O)nc(SCC(=O)N2CCN(CC2)c3ccccc3)n1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P16 compound treatment 421189.0 -1440000.0 -2.7 407577.0 -1320000.0 -2.64 -3.7775 -0.9999 3632537 CBKinase1_022632 Oc1c(ccc2cccnc12)C(Nc3ccccn3)c4cccc(OC5CCCC5)c4 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P17 compound treatment 1302649.0 -559000.0 -1.05 1328679.0 -399000.0 -0.8 -1.3056 -0.9907 1445173 CBKinase1_022633 Fc1ccc(NC(=O)COc2ccc3c(=O)c(coc3c2)c4ccccc4)cc1 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P18 compound treatment 1126736.0 -735000.0 -1.38 1114086.0 -613000.0 -1.23 -1.8424 -0.9982 3632538 CBKinase1_022634 Cc1ccc(cc1NC(=O)C2(CCN(CC2)S(=O)(=O)c3ccccc3)c4ccccc4)[N+](=O)[O-] 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P19 compound treatment 952035.0 -910000.0 -1.71 985802.0 -741000.0 -1.48 -2.2556 -0.9975 1204329 CBKinase1_022635 COc1ccccc1C(=O)Oc2c(CN3CCOCC3)cc(Cl)c4cccnc24 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P20 compound treatment 1020598.0 -841000.0 -1.58 1166835.0 -560000.0 -1.12 -1.9087 -0.9858 3632539 CBKinase1_022636 Cc1ccc(NC(=O)COc2ccc(I)cc2)c(c1)C(=O)O 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P21 compound treatment 1174923.0 -687000.0 -1.29 1354043.0 -373000.0 -0.75 -1.4393 -0.9661 3632540 CBKinase1_022637 CCN(CC(=O)Nc1ccccc1OC)S(=O)(=O)c2ccc3ccccc3c2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P22 compound treatment 1202924.0 -659000.0 -1.24 1148586.0 -579000.0 -1.16 -1.6925 -0.9994 3632541 CBKinase1_022638 O=C(NCc1ccco1)c2ccc(NC(=O)c3ccccc3)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P23 compound treatment 1094948.0 -767000.0 -1.44 896219.0 -831000.0 -1.66 -2.1925 -0.9975 3632542 CBKinase1_022639 CCN(CC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F)S(=O)(=O)c2ccc(C)cc2 1010.0038 DAPIStaining(1010.0038) PlasmodiumViabilityAssay 1010.0038.2394 P24 compound treatment 974588.0 -887000.0 -1.67 855705.0 -872000.0 -1.74 -2.4095 -0.9997 3632543 CBKinase1_022640 Cc1cccc(C)c1OCC(=O)Nc2cccc(NC(=O)c3ccco3)c2