ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A01 compound treatment 946168.0 39800.0 0.22 1062291.0 61900.0 0.35 0.4002 0.9739 3624959 CBKinase1_014001 Cc1ccc(cc1)S(=O)(=O)Nc2nc(C)cc(n2)N3N=N3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A02 compound treatment 851750.0 -54700.0 -0.3 1143340.0 143000.0 0.81 0.3588 0.4175 1171663 CBKinase1_014002 CCC(=O)Nc1cccc(NC(=O)COc2cc(C)cc(C)c2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A03 compound treatment 932588.0 26200.0 0.14 1095395.0 95000.0 0.54 0.4798 0.8655 3624960 CBKinase1_014003 COc1ccc(CCNc2oc(nc2C#N)c3ccc(C)cc3)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A04 compound treatment 881505.0 -24900.0 -0.14 1075998.0 75600.0 0.43 0.2052 0.4587 3624961 CBKinase1_014004 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2ccc(Oc3cccnc3)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A05 compound treatment 833291.0 -73100.0 -0.4 1058389.0 58000.0 0.33 -0.0511 -0.0989 3023144 CBKinase1_014005 COC(=O)CSc1nc(C)c(Br)c(O)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A06 compound treatment 892412.0 -14000.0 -0.08 979244.0 -21100.0 -0.12 -0.1383 -0.977 1446177 CBKinase1_014006 O=S(=O)(NC1C(Sc2nnnn2c3ccccc3)c4cccc5cccc1c45)c6ccccc6 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A07 compound treatment 827586.0 -78800.0 -0.43 1013055.0 12700.0 0.07 -0.2538 -0.5817 3624962 CBKinase1_014007 OC(=O)CC(Cc1ccccc1)C(=O)Nc2ccc(Cl)c(Cl)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A08 compound treatment 847880.0 -58500.0 -0.32 1019939.0 19600.0 0.11 -0.148 -0.4377 3624963 CBKinase1_014008 CCOC(=O)c1ccc(NC(=O)C2CC(=C(C)CC2C(=O)O)C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A09 compound treatment 814232.0 -92200.0 -0.5 991124.0 -9250.0 -0.05 -0.3927 -0.7762 1123229 CBKinase1_014009 OC(COc1ccc(Br)cc1)CN2C(=O)c3ccccc3S2(=O)=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A10 compound treatment 864001.0 -42400.0 -0.23 1203622.0 203000.0 1.15 0.6463 0.553 1701183 CBKinase1_014010 COc1cc(ccc1OCc2ccc(Cl)cc2)C(=O)Nc3cc(ccc3C)c4nc5ncccc5o4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A11 compound treatment 803040.0 -103000.0 -0.56 1036095.0 35700.0 0.2 -0.2567 -0.4284 3624964 CBKinase1_014011 OC1=C(C(N(CCCn2ccnc2)C1=O)c3cccc(Br)c3)C(=O)c4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A12 compound treatment 808315.0 -98100.0 -0.54 945991.0 -54400.0 -0.31 -0.5954 -0.9649 1503623 CBKinase1_014012 Cc1cc(Cl)ccc1OCC(=O)Nc2cccc(NC(=O)c3ccccc3Cl)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A13 mock treatment 849400.0 -57000.0 -0.31 1116715.0 116000.0 0.66 0.2436 0.3356 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A14 mock treatment 826147.0 -80300.0 -0.44 1096155.0 95800.0 0.54 0.0719 0.1034 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A15 compound treatment 1050435.0 144000.0 0.79 1024607.0 24200.0 0.14 0.6526 0.8177 3624965 CBKinase1_014013 CC(C)c1ccc2oc(nc2c1)c3ccc(Cl)c(NC(=O)COc4ccc(cc4)[N+](=O)[O-])c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A16 compound treatment 889768.0 -16600.0 -0.09 1036414.0 36000.0 0.2 0.0794 0.3567 3624966 CBKinase1_014014 COc1ccccc1OCC(=O)Nc2c[nH]c(=O)[nH]c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A17 compound treatment 835311.0 -71100.0 -0.39 1014584.0 14200.0 0.08 -0.2179 -0.5496 1682839 CBKinase1_014015 OC1=C(C(N(Cc2cccnc2)C1=O)c3ccc(Br)cc3)C(=O)c4cccs4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A18 compound treatment 769629.0 -137000.0 -0.75 1011194.0 10800.0 0.06 -0.4849 -0.6472 3624967 CBKinase1_014016 Cc1c(NC(=O)CN(c2cccc(C)c2)S(=O)(=O)C)c(=O)n(c3ccccc3)n1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A19 compound treatment 848707.0 -57700.0 -0.32 1151119.0 151000.0 0.85 0.378 0.4172 3624968 CBKinase1_014017 COc1ccc(OC)c(NC(=O)COc2ccc(cc2)[N+](=O)[O-])c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A20 compound treatment 810646.0 -95800.0 -0.52 1106552.0 106000.0 0.6 0.0535 0.0673 1156802 CBKinase1_014018 Cc1cc(C)n(n1)C(=O)CCC(=O)Nc2cc(C)ccc2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A21 compound treatment 758466.0 -148000.0 -0.81 1101657.0 101000.0 0.57 -0.1675 -0.1693 3624969 CBKinase1_014019 Cc1cc(C)c(OCC(=O)Nc2cccc(NC(=O)c3ccccc3C)c2)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A22 compound treatment 783322.0 -123000.0 -0.67 892886.0 -107000.0 -0.61 -0.9036 -0.9987 3624970 CBKinase1_014020 COc1ccc(Cl)cc1N(CC(=O)Nc2ccccc2F)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A23 compound treatment 791055.0 -115000.0 -0.63 817707.0 -183000.0 -1.03 -1.1734 -0.9722 3624971 CBKinase1_014021 [O-][N+](=O)c1ccc(OCC(=O)Nc2cccc(NC(=O)c3ccccc3Cl)c2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 A24 compound treatment 771196.0 -135000.0 -0.74 872309.0 -128000.0 -0.72 -1.0324 -0.9999 3211926 CBKinase1_014022 OC(=O)c1ccccc1NC(=O)CCSc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B01 compound treatment 937608.0 31200.0 0.17 990390.0 -9980.0 -0.06 0.0806 0.4496 1560009 CBKinase1_014023 COC(=O)c1ccccc1NC(=O)COc2cc(C)ccc2C(C)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B02 compound treatment 922242.0 15800.0 0.09 960948.0 -39400.0 -0.22 -0.096 -0.4028 3624972 CBKinase1_014024 COc1ccc(Cl)cc1NC(=O)COc2ccc(cc2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B03 compound treatment 975912.0 69500.0 0.38 855345.0 -145000.0 -0.82 -0.3097 -0.3437 1148448 CBKinase1_014025 Cc1ccccc1C(=O)Nc2cccc(NC(=O)COc3ccc(Cl)cc3C)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B04 compound treatment 950869.0 44500.0 0.24 1106740.0 106000.0 0.6 0.5955 0.9208 1203624 CBKinase1_014026 CCOC(=O)c1sc2ncn(CC(=O)Nc3ccc(OC)cc3)c(=O)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B05 compound treatment 956730.0 50300.0 0.27 932487.0 -67900.0 -0.38 -0.0763 -0.162 1173206 CBKinase1_014027 Cc1cc(C)c2oc(nc2c1)c3cccc(NC(=O)COc4ccc(Cl)cc4)c3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B06 compound treatment 927180.0 20800.0 0.11 936223.0 -64100.0 -0.36 -0.1755 -0.4632 3624973 CBKinase1_014028 COc1ccc(NC(=O)CN(C2CCCCC2)S(=O)(=O)c3ccc(Cl)cc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B07 compound treatment 925064.0 18600.0 0.1 1013878.0 13500.0 0.08 0.1258 0.9897 1925269 CBKinase1_014029 [O-][N+](=O)c1ccccc1OCC(=O)Nc2ccc3oc(nc3c2)c4ccc(Br)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B08 compound treatment 878533.0 -27900.0 -0.15 877310.0 -123000.0 -0.69 -0.5981 -0.8422 1397847 CBKinase1_014030 Ic1ccc(cc1)S(=O)(=O)NCc2ccccn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B09 compound treatment 879413.0 -27000.0 -0.15 1039442.0 39100.0 0.22 0.0515 0.1942 1927682 CBKinase1_014031 [O-][N+](=O)c1ccccc1OCC(=O)Nc2ccc3oc(nc3c2)c4cccc(Br)c4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B10 compound treatment 815425.0 -91000.0 -0.5 930916.0 -69500.0 -0.39 -0.6281 -0.993 3624974 CBKinase1_014032 FC(F)(F)c1ccccc1NC(=O)CN(C2CCCCC2)S(=O)(=O)c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B11 compound treatment 1725461.0 819000.0 4.47 2073320.0 1070000.0 6.05 7.4382 0.989 1321727 CBKinase1_014033 Fc1ccc(cc1)n2nc3ccc(NC(=O)COc4ccc(Cl)cc4)cc3n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B12 compound treatment 912471.0 6060.0 0.03 933188.0 -67200.0 -0.38 -0.2444 -0.6429 1865043 CBKinase1_014034 Cc1ccc(cc1)S(=O)(=O)NCCC(=O)Oc2ccc3c(=O)c(coc3c2)c4ccc(F)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B13 mock treatment 885070.0 -21300.0 -0.12 952148.0 -48200.0 -0.27 -0.2746 -0.9285 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B14 mock treatment 847991.0 -58400.0 -0.32 955011.0 -45400.0 -0.26 -0.4063 -0.994 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B15 compound treatment 868041.0 -38400.0 -0.21 970216.0 -30200.0 -0.17 -0.2683 -0.9946 1630473 CBKinase1_014035 Cc1ccc(OCC(=O)Nc2ccccc2C(=O)Nc3ccccc3)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B16 compound treatment 889533.0 -16900.0 -0.09 925862.0 -74500.0 -0.42 -0.3621 -0.8422 3624975 CBKinase1_014036 Brc1ccc(NC(=O)c2c(NC(=O)CN3CCCCC3)sc4CCCc24)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B17 compound treatment 857632.0 -48800.0 -0.27 978839.0 -21500.0 -0.12 -0.2741 -0.9367 3624976 CBKinase1_014037 CC1(C)CC(=O)c2cc(C(=O)NCCCN3CCOCC3)c(=O)n(c4ccccc4)c2C1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B18 compound treatment 890501.0 -15900.0 -0.09 914613.0 -85800.0 -0.48 -0.4032 -0.821 1870511 CBKinase1_014038 O=C(NCc1ccco1)c2c(NC(=O)c3cccs3)sc4CCCCc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B19 compound treatment 828026.0 -78400.0 -0.43 946710.0 -53700.0 -0.3 -0.5165 -0.9856 3624977 CBKinase1_014039 CC(=O)Nc1cccc(NC(=O)CSc2ccccc2[N+](=O)[O-])c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B20 compound treatment 800604.0 -106000.0 -0.58 919073.0 -81300.0 -0.46 -0.7325 -0.9934 3624978 CBKinase1_014040 Brc1ccc(NC(=O)c2c(NC(=O)CN3CCOCC3)sc4CCCc24)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B21 compound treatment 775370.0 -131000.0 -0.72 978970.0 -21400.0 -0.12 -0.5912 -0.8148 3624979 CBKinase1_014041 Brc1ccccc1NC(=O)CCCN2C(=O)c3cccc4cccc(C2=O)c34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B22 compound treatment 794349.0 -112000.0 -0.61 947558.0 -52800.0 -0.3 -0.6431 -0.9452 3624980 CBKinase1_014042 COc1ccccc1c2nnc(SCC(=O)Nc3ccc(Cl)cc3Cl)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B23 compound treatment 565271.0 -341000.0 -1.86 647470.0 -353000.0 -1.99 -2.7235 -0.9995 3624981 CBKinase1_014043 CC(C)OC(=O)CS(=O)c1ccc(cc1[N+](=O)[O-])C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 B24 compound treatment 752835.0 -154000.0 -0.84 1193738.0 193000.0 1.09 0.1778 0.1293 3624982 CBKinase1_014044 Ic1ccccc1C(=O)Nc2ccccc2C(=O)NCCOc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C01 compound treatment 939792.0 33400.0 0.18 1080969.0 80600.0 0.45 0.4501 0.9195 3624983 CBKinase1_014045 [O-][N+](=O)c1ccccc1NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)Nc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C02 compound treatment 991005.0 84600.0 0.46 1137030.0 137000.0 0.77 0.8712 0.9701 1297555 CBKinase1_014046 CCC(=O)Nc1cccc(NC(=O)COc2cc(Cl)c(Cl)cc2Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C03 compound treatment 901647.0 -4770.0 -0.03 944232.0 -56100.0 -0.32 -0.2422 -0.7627 1144753 CBKinase1_014047 Clc1ccc(cc1Cl)S(=O)(=O)c2cccc(c2)S(=O)(=O)Nc3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C04 compound treatment 944842.0 38400.0 0.21 1145476.0 145000.0 0.82 0.7267 0.8606 3624984 CBKinase1_014048 Cc1ccc(cc1NC(=O)Cn2cnc3ccccc3c2=O)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C05 compound treatment 1002425.0 96000.0 0.52 1102827.0 102000.0 0.58 0.779 0.9988 1739363 CBKinase1_014049 COC(=O)c1c(NC(=O)COc2ccc(C(C)C)c(C)c2)sc3CCCc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C06 compound treatment 912952.0 6540.0 0.04 1114513.0 114000.0 0.64 0.4802 0.7452 1406123 CBKinase1_014050 Clc1ccc(C(=O)Nc2sc3CCCCc3c2C(=O)NCC4CCCO4)c(Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C07 compound treatment 1076245.0 170000.0 0.93 1060102.0 59700.0 0.34 0.8937 0.906 3624985 CBKinase1_014051 [O-][N+](=O)c1ccccc1NC(=O)c2cc(ccc2Cl)S(=O)(=O)Nc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C08 compound treatment 1018036.0 112000.0 0.61 963702.0 -36700.0 -0.21 0.2848 0.4425 1975046 CBKinase1_014052 FC(F)(F)c1cc(NC(=O)C(Cc2ccccc2)N3C(=O)C4CCCCC4C3=O)ccc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C09 compound treatment 846390.0 -60000.0 -0.33 914418.0 -86000.0 -0.48 -0.5743 -0.9819 1367660 CBKinase1_014053 Cc1nc2ccccc2n1CC(O)COc3ccc(cc3)C4CCC=C4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C10 compound treatment 1296251.0 390000.0 2.13 1067488.0 67100.0 0.38 1.7724 0.8199 1579913 CBKinase1_014054 CCOC(=O)Cc1cc(=O)nc(Nc2nc3ccccc3o2)[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C11 mock treatment 991047.0 84600.0 0.46 861086.0 -139000.0 -0.79 -0.2284 -0.2507 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C12 mock treatment 1023928.0 118000.0 0.64 1511263.0 511000.0 2.88 2.4898 0.844 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C13 compound treatment 949659.0 43200.0 0.24 977611.0 -22800.0 -0.13 0.0762 0.2837 1602625 CBKinase1_014055 COc1ccc(OC)c(NC(=O)C2=C(C)NC(=O)NC2c3ccc(OC)cc3OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C14 compound treatment 964303.0 57900.0 0.32 1026815.0 26400.0 0.15 0.3289 0.9412 3624986 CBKinase1_014056 CC(Sc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccc(Cl)cc3Cl)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C15 mock treatment 889645.0 -16800.0 -0.09 1012341.0 12000.0 0.07 -0.017 -0.1498 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C16 mock treatment 1014082.0 108000.0 0.59 1138953.0 139000.0 0.78 0.968 0.9902 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C17 compound treatment 905417.0 -998.0 -0.01 1016295.0 15900.0 0.09 0.0596 0.663 1152555 CBKinase1_014057 Cc1ccc(o1)C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c4cccc(Oc5ccccc5)c4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C18 compound treatment 924185.0 17800.0 0.1 1116089.0 116000.0 0.65 0.5298 0.8034 1636512 CBKinase1_014058 CCOc1ccc(Br)cc1S(=O)(=O)n2nnc3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C19 compound treatment 1114159.0 208000.0 1.13 1030281.0 29900.0 0.17 0.9212 0.8034 3624987 CBKinase1_014059 COc1ccc(cc1Cl)n2nc3cc(C)c(NC(=S)NC(=O)COc4cccc(C)c4)cc3n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C20 compound treatment 780682.0 -126000.0 -0.69 1009207.0 8830.0 0.05 -0.4502 -0.6541 3624988 CBKinase1_014060 COc1ccc(C)cc1NC(=O)CN(c2ccc(Cl)cc2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C21 compound treatment 996446.0 90000.0 0.49 980631.0 -19700.0 -0.11 0.2689 0.5335 3624989 CBKinase1_014061 Cc1ccccc1NC(=O)CN(c2ccc(Cl)c(Cl)c2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C22 compound treatment 927625.0 21200.0 0.12 986349.0 -14000.0 -0.08 0.026 0.1854 1730540 CBKinase1_014062 C=CCc1cccc2cc(C(=O)NCCN3CCOCC3)c(=O)oc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C23 compound treatment 894678.0 -11700.0 -0.06 1046189.0 45800.0 0.26 0.1373 0.516 1589938 CBKinase1_014063 Cc1cccc(OCC(=O)Nc2ccc(Cl)c(c2)c3nc4ccccc4s3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 C24 compound treatment 983024.0 76600.0 0.42 899918.0 -100000.0 -0.57 -0.1046 -0.1486 3624990 CBKinase1_014064 Cc1ccc(cc1)n2nc3ccc(NC(=O)COc4cccc(C)c4)cc3n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D01 compound treatment 1030090.0 124000.0 0.68 1034688.0 34300.0 0.19 0.6142 0.8745 1928817 CBKinase1_014065 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4cccc(Cl)c4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D02 compound treatment 908134.0 1720.0 0.01 915813.0 -84600.0 -0.48 -0.3304 -0.693 3624991 CBKinase1_014066 [O-][N+](=O)c1cccc(c1)c2csc3ncn(CC(=O)Nc4ccc(Cl)cc4)c(=O)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D03 compound treatment 1023268.0 117000.0 0.64 901972.0 -98400.0 -0.55 0.0589 0.0697 1439628 CBKinase1_014067 Cc1cc(OCC(=O)Nc2ccc(O)c(c2)c3nc4ccccc4s3)ccc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D04 compound treatment 1043368.0 137000.0 0.75 907547.0 -92800.0 -0.52 0.1587 0.174 1366770 CBKinase1_014068 COc1ccc(cc1)c2csc3ncn(CC(=O)Nc4ccccc4)c(=O)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D05 compound treatment 993567.0 87200.0 0.48 996722.0 -3650.0 -0.02 0.3219 0.6759 1176261 CBKinase1_014069 COc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)N)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D06 compound treatment 812782.0 -93600.0 -0.51 692330.0 -308000.0 -1.74 -1.5892 -0.878 3624992 CBKinase1_014070 CC(C)(C)c1ccc(OCc2nnc(Sc3ccc(cn3)[N+](=O)[O-])n2c4ccccc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D07 compound treatment 1000154.0 93700.0 0.51 955097.0 -45300.0 -0.26 0.1814 0.3173 1946914 CBKinase1_014071 Cc1ccc(cc1NC(=O)COc2ccc(cc2)[N+](=O)[O-])c3nc4cc(C)c(C)cc4o3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D08 compound treatment 1009330.0 103000.0 0.56 918938.0 -81400.0 -0.46 0.0727 0.1003 3624993 CBKinase1_014072 COc1ccc(NC(=O)CN(C2CCCCC2)S(=O)(=O)c3ccc(C)cc3)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D09 compound treatment 935720.0 29300.0 0.16 972082.0 -28300.0 -0.16 4.0E-4 0.0017 1485655 CBKinase1_014073 Cc1ccc(cc1NC(=O)COc2ccc(Cl)c(C)c2)c3nc4ccccc4o3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D10 compound treatment 924844.0 18400.0 0.1 944823.0 -55500.0 -0.31 -0.1502 -0.4569 3624994 CBKinase1_014074 COc1ccccc1NC(=O)c2ccc(NC(=O)C3COc4ccccc4O3)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D11 mock treatment 931220.0 24800.0 0.14 942395.0 -58000.0 -0.33 -0.1353 -0.3825 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D12 mock treatment 912777.0 6360.0 0.03 936592.0 -63800.0 -0.36 -0.2296 -0.6358 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D13 compound treatment 955821.0 49400.0 0.27 913013.0 -87400.0 -0.49 -0.1574 -0.2804 1305890 CBKinase1_014075 Cc1cccc(OCC(=O)Nc2cc(ccc2C)c3nc4ccccc4s3)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D14 compound treatment 1000858.0 94400.0 0.52 920654.0 -79700.0 -0.45 0.0469 0.0685 1870516 CBKinase1_014076 Cc1ccccc1C(=O)Nc2sc3CCCCc3c2C(=O)NCc4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D15 mock treatment 999584.0 93200.0 0.51 923750.0 -76600.0 -0.43 0.0543 0.0814 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D16 mock treatment 1028645.0 122000.0 0.67 1022687.0 22300.0 0.13 0.5608 0.8258 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D17 compound treatment 944691.0 38300.0 0.21 944546.0 -55800.0 -0.31 -0.0747 -0.1978 1595007 CBKinase1_014077 Nc1cc(=O)nc(SCC(=O)N2c3ccccc3Sc4ccccc24)n1c5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D18 compound treatment 950739.0 44300.0 0.24 1050291.0 49900.0 0.28 0.3701 0.9972 3624995 CBKinase1_014078 CCOc1ccc(NC(=O)c2c(NC(=O)CN(C)C)sc3CCCc23)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D19 compound treatment 881400.0 -25000.0 -0.14 984167.0 -16200.0 -0.09 -0.1612 -0.9809 3624996 CBKinase1_014079 COC(=O)c1ccc(C)c(NC(=O)CN(c2ccc(Cl)c(Cl)c2)S(=O)(=O)C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D20 compound treatment 912586.0 6170.0 0.03 1029122.0 28700.0 0.16 0.1384 0.8362 3624997 CBKinase1_014080 CC(C)Oc1ccccc1NC(=O)CSc2nnc(o2)c3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D21 compound treatment 940893.0 34500.0 0.19 911819.0 -88600.0 -0.5 -0.2198 -0.4121 3624998 CBKinase1_014081 COc1cccc(OCC(=O)Nc2ccccc2[N+](=O)[O-])c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D22 compound treatment 556201.0 -350000.0 -1.91 646706.0 -354000.0 -1.99 -2.7615 -0.9998 3624999 CBKinase1_014082 Cc1ccc2ccc(C(Nc3ccccn3)c4ccccc4Cl)c(O)c2n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D23 compound treatment 846873.0 -59500.0 -0.33 834879.0 -165000.0 -0.93 -0.8894 -0.9004 3625000 CBKinase1_014083 COc1ccc(cc1)C(=O)Nc2ccc(Cc3ccc(NC(=O)c4ccc(OC)cc4)c(O)c3)cc2O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 D24 compound treatment 861723.0 -44700.0 -0.24 1005612.0 5240.0 0.03 -0.1516 -0.617 3625001 CBKinase1_014084 Cc1sc2nc(SCC(=O)NCc3ccco3)n(C)c(=O)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E01 mock treatment 854045.0 -52400.0 -0.29 943937.0 -56400.0 -0.32 -0.4271 -0.9986 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E02 mock treatment 878407.0 -28000.0 -0.15 944196.0 -56200.0 -0.32 -0.332 -0.9442 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E03 compound treatment 755986.0 -150000.0 -0.82 910840.0 -89500.0 -0.5 -0.9376 -0.9727 1415345 CBKinase1_014085 Clc1ccc(cc1)n2c(SCC(=O)Nc3cccc(Cl)c3)nc4ccccc4c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E04 compound treatment 879431.0 -27000.0 -0.15 979095.0 -21300.0 -0.12 -0.189 -0.9948 3625002 CBKinase1_014086 CC(N(c1ccccc1)S(=O)(=O)C)C(=O)Nc2ccc(C)c(C)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E05 compound treatment 823048.0 -83400.0 -0.46 1040765.0 40400.0 0.23 -0.1608 -0.3161 3625003 CBKinase1_014087 N#Cc1ccccc1CSc2ncn[nH]2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E06 compound treatment 758403.0 -148000.0 -0.81 1017682.0 17300.0 0.1 -0.5024 -0.6172 3625004 CBKinase1_014088 FC(F)(F)c1nc2ccccc2n1CC(=O)NCc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E07 compound treatment 892999.0 -13400.0 -0.07 879547.0 -121000.0 -0.68 -0.5333 -0.7787 1635829 CBKinase1_014089 OC(=O)c1cccc(NS(=O)(=O)c2cccc(c2)C(=O)Nc3ccc(F)cc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E08 compound treatment 731599.0 -175000.0 -0.95 916514.0 -83900.0 -0.47 -1.0091 -0.9475 1733234 CBKinase1_014090 CCc1ccc(OCC(=O)Nc2ccccc2C#N)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E09 mock treatment 706119.0 -200000.0 -1.09 901724.0 -98600.0 -0.56 -1.1664 -0.9508 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E10 mock treatment 755655.0 -151000.0 -0.82 869249.0 -131000.0 -0.74 -1.1046 -0.9986 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E11 compound treatment 717270.0 -189000.0 -1.03 957256.0 -43100.0 -0.24 -0.902 -0.8503 1667112 CBKinase1_014091 CCOc1ccc(cc1)n2c(SCc3nc4ccccc4[nH]3)nc5sc6CCCCc6c5c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E12 compound treatment 882236.0 -24200.0 -0.13 906538.0 -93800.0 -0.53 -0.4673 -0.8573 1479340 CBKinase1_014092 Cc1ccc(cc1NC(=O)COc2cc(Cl)c(Cl)cc2Cl)c3nc4ncccc4o3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E13 compound treatment 801369.0 -105000.0 -0.57 961760.0 -38600.0 -0.22 -0.5594 -0.912 1284691 CBKinase1_014093 CC1CCc2c(C#N)c(NC(=O)CCN3C(=O)c4ccccc4C3=O)sc2C1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E14 compound treatment 794597.0 -112000.0 -0.61 862434.0 -138000.0 -0.78 -0.9814 -0.9928 1726901 CBKinase1_014094 Brc1cncc(c1)C(=O)NCc2ccco2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E15 compound treatment 766186.0 -140000.0 -0.77 1001087.0 715.0 0.0 -0.5385 -0.7034 3625005 CBKinase1_014095 COc1ccccc1N(CC(=O)Nc2ccccc2Cl)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E16 compound treatment 708792.0 -198000.0 -1.08 931394.0 -69000.0 -0.39 -1.0378 -0.905 1588243 CBKinase1_014096 COc1ccc(OCC(=O)Nc2cccc(c2)c3nc4ccccc4c(=O)o3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E17 mock treatment 790372.0 -116000.0 -0.63 984869.0 -15500.0 -0.09 -0.5098 -0.7971 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E18 mock treatment 836583.0 -69800.0 -0.38 914964.0 -85400.0 -0.48 -0.61 -0.9933 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E19 compound treatment 882569.0 -23800.0 -0.13 959296.0 -41100.0 -0.23 -0.2558 -0.9629 3625006 CBKinase1_014097 CCc1ccc(Nc2nc3ccccc3nc2NS(=O)(=O)c4ccc(NC(=O)C)cc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E20 compound treatment 718240.0 -188000.0 -1.03 815237.0 -185000.0 -1.04 -1.4643 -1.0 3625007 CBKinase1_014098 CN1CCN(CC1)C(=O)CN(c2c(C)cccc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E21 compound treatment 791010.0 -115000.0 -0.63 845796.0 -155000.0 -0.87 -1.0616 -0.9873 3625008 CBKinase1_014099 CS(=O)(=O)N(CC(=O)Nc1ccc(I)cc1)c2ccc(Cl)c(Cl)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E22 compound treatment 639341.0 -267000.0 -1.46 990990.0 -9380.0 -0.05 -1.0684 -0.7323 3625009 CBKinase1_014100 Cc1ccc(Cl)cc1NC(=O)CN(c2ccc(Cl)cc2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E23 compound treatment 740215.0 -166000.0 -0.91 937414.0 -63000.0 -0.35 -0.8925 -0.9161 1666952 CBKinase1_014101 Cc1ccc(OCC(=O)Nc2cc(ccc2C)c3nc4cc(Cl)ccc4o3)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 E24 compound treatment 716739.0 -190000.0 -1.04 898916.0 -101000.0 -0.57 -1.1366 -0.9608 3625010 CBKinase1_014102 CS(=O)(=O)N(CC(=O)Nc1ccc(F)cc1)c2cccc(Br)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F01 mock treatment 822510.0 -83900.0 -0.46 907708.0 -92700.0 -0.52 -0.6932 -0.9979 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F02 mock treatment 870806.0 -35600.0 -0.19 898319.0 -102000.0 -0.58 -0.5442 -0.8963 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F03 compound treatment 861290.0 -45100.0 -0.25 870107.0 -130000.0 -0.73 -0.6934 -0.8953 1346156 CBKinase1_014103 COc1ccc(OC)c(NC(=O)CN(c2ccccc2Br)S(=O)(=O)C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F04 compound treatment 771143.0 -135000.0 -0.74 957700.0 -42700.0 -0.24 -0.6923 -0.8913 3625011 CBKinase1_014104 COc1ccc(cc1)c2c(C)[nH]nc2c3ccc(OCc4cnn(c4)c5ccccc5)c(C)c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F05 compound treatment 887952.0 -18500.0 -0.1 885535.0 -115000.0 -0.65 -0.529 -0.8075 1185235 CBKinase1_014105 Ic1ccc(OCC(=O)Nc2cccnc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F06 compound treatment 791332.0 -115000.0 -0.63 851409.0 -149000.0 -0.84 -1.038 -0.9898 1197230 CBKinase1_014106 COC(=O)c1ccc(NC(=O)C2Cc3ccccc3CN2S(=O)(=O)c4ccc(F)cc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F07 compound treatment 775902.0 -131000.0 -0.71 864809.0 -136000.0 -0.76 -1.0441 -0.9994 1152523 CBKinase1_014107 Cc1cccc(OCC(=O)Nc2cccc(c2)c3nc4ccccc4s3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F08 compound treatment 2416231.0 1510000.0 8.24 1723057.0 723000.0 4.07 8.7089 0.9472 3625012 CBKinase1_014108 CC[C@H](NS(=O)(=O)c1ccc(C)cc1)C(=O)Oc2cc3oc(=O)cc(C)c3cc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F09 mock treatment 890920.0 -15500.0 -0.08 920597.0 -79800.0 -0.45 -0.3778 -0.8257 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F10 mock treatment 809574.0 -96800.0 -0.53 901968.0 -98400.0 -0.55 -0.766 -0.9997 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F11 compound treatment 853725.0 -52700.0 -0.29 878332.0 -122000.0 -0.69 -0.6898 -0.9252 1946991 CBKinase1_014109 Cc1cc2nc(oc2cc1C)c3ccc(NC(=O)COc4ccccc4[N+](=O)[O-])cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F12 compound treatment 857879.0 -48500.0 -0.26 860022.0 -140000.0 -0.79 -0.7467 -0.8951 1411625 CBKinase1_014110 Cc1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccccc4C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F13 compound treatment 730919.0 -175000.0 -0.96 920578.0 -79800.0 -0.45 -0.9955 -0.9406 3625013 CBKinase1_014111 Cc1cc(C)nc(SC2CCCCC2NS(=O)(=O)c3ccc(Cl)cc3)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F14 compound treatment 864177.0 -42200.0 -0.23 793561.0 -207000.0 -1.17 -0.9873 -0.8309 3625014 CBKinase1_014112 CCc1cccc(C)c1NC(=O)CSc2nnc(c3ccc(Cl)cc3Cl)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F15 compound treatment 683612.0 -223000.0 -1.22 860430.0 -140000.0 -0.79 -1.4179 -0.978 3625015 CBKinase1_014113 Cc1cc(=O)nc(SCc2nc3ccc(cc3[nH]2)[N+](=O)[O-])[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F16 compound treatment 848525.0 -57900.0 -0.32 841285.0 -159000.0 -0.9 -0.8575 -0.902 3625016 CBKinase1_014114 Cc1cc(Br)ccc1OCC(=O)Nc2ccccc2[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F17 mock treatment 761596.0 -145000.0 -0.79 904932.0 -95400.0 -0.54 -0.9394 -0.9824 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F18 mock treatment 918769.0 12400.0 0.07 838236.0 -162000.0 -0.91 -0.5985 -0.6531 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F19 compound treatment 868400.0 -38000.0 -0.21 894376.0 -106000.0 -0.6 -0.5692 -0.9 3625017 CBKinase1_014115 COc1ccc(N(CC(=O)N2CCN(CC2)c3ccccc3F)S(=O)(=O)C)c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F20 compound treatment 737974.0 -168000.0 -0.92 781153.0 -219000.0 -1.24 -1.524 -0.9894 3625018 CBKinase1_014116 CCc1cccc(C)c1NC(=O)CSc2nnc(c3ccc(C)cc3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F21 compound treatment 674685.0 -232000.0 -1.27 763285.0 -237000.0 -1.34 -1.8395 -0.9996 3625019 CBKinase1_014117 COc1cccc(c1)c2cc(C#N)c(NC(=O)c3cccc(c3)[N+](=O)[O-])o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F22 compound treatment 714210.0 -192000.0 -1.05 872305.0 -128000.0 -0.72 -1.2524 -0.9833 1736675 CBKinase1_014118 COc1cc(NS(=O)(=O)c2ccc(NC(=O)C3(CC4CC5CC(C4)C3)C5)cc2)ncn1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F23 compound treatment 737092.0 -169000.0 -0.92 852993.0 -147000.0 -0.83 -1.241 -0.9986 3625020 CBKinase1_014119 COc1ccc(CC(=O)Nc2ccc(O)cc2C(=O)O)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 F24 compound treatment 715128.0 -191000.0 -1.04 848177.0 -152000.0 -0.86 -1.345 -0.9952 3625021 CBKinase1_014120 COc1ccc(cc1O)C(Nc2cc(C)ccn2)c3ccc4cccnc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G01 compound treatment 954653.0 48200.0 0.26 1160213.0 160000.0 0.9 0.8233 0.8771 1667602 CBKinase1_014121 COc1ccc(cc1)C(=O)c2oc3ccccc3c2NC(=O)COc4ccc(F)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G02 compound treatment 920529.0 14100.0 0.08 1107446.0 107000.0 0.6 0.4812 0.791 3625022 CBKinase1_014122 CC(=O)c1ccc(NC(=O)CCC(=O)Oc2ccc(C)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G03 mock treatment 871450.0 -35000.0 -0.19 1051124.0 50800.0 0.29 0.0673 0.1957 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G04 mock treatment 872630.0 -33800.0 -0.18 1067071.0 66700.0 0.38 0.1354 0.3234 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G05 compound treatment 907524.0 1110.0 0.01 1071622.0 71200.0 0.4 0.2883 0.7177 3625023 CBKinase1_014123 CN(C)CCN1C(C(=C(O)C1=O)C(=O)c2cccs2)c3ccc(C)o3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G06 compound treatment 812259.0 -94200.0 -0.51 1091647.0 91300.0 0.51 3.0E-4 4.0E-4 1467768 CBKinase1_014124 Cc1ccc2nc(SCc3nc4ccccc4n3C)[nH]c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G07 compound treatment 880511.0 -25900.0 -0.14 1011649.0 11300.0 0.06 -0.0551 -0.3551 3625024 CBKinase1_014125 O=C(NCCCN1CCOCC1)c2cccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G08 compound treatment 885610.0 -20800.0 -0.11 1059689.0 59300.0 0.33 0.1561 0.4421 3625025 CBKinase1_014126 CCc1ccc(cc1)n2nc3ccc(NC(=O)COc4ccccc4[N+](=O)[O-])cc3n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G09 compound treatment 881179.0 -25200.0 -0.14 1108713.0 108000.0 0.61 0.3344 0.5341 1436221 CBKinase1_014127 OC1=C(C(N(CCCn2ccnc2)C1=O)c3ccc(Cl)cc3)C(=O)c4cccs4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G10 compound treatment 862415.0 -44000.0 -0.24 1039609.0 39200.0 0.22 -0.0135 -0.0413 3625026 CBKinase1_014128 O=C(Cn1c(nc2ccccc12)c3cncs3)NCc4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G11 compound treatment 802798.0 -104000.0 -0.57 1081857.0 81500.0 0.46 -0.0752 -0.1033 1629784 CBKinase1_014129 OC1=C(C(N(CCN2CCOCC2)C1=O)c3ccc(Cl)cc3)C(=O)c4cccs4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G12 compound treatment 869358.0 -37100.0 -0.2 1009569.0 9200.0 0.05 -0.1064 -0.5095 1661309 CBKinase1_014130 O=C(CSc1nc2cccnc2[nH]1)NCc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G13 compound treatment 856606.0 -49800.0 -0.27 1036242.0 35900.0 0.2 -0.0493 -0.1456 1271125 CBKinase1_014131 CC(=C)Cn1c(SCc2nc3ccccc3[nH]2)nc4sc5CCCCc5c4c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G14 compound treatment 820293.0 -86100.0 -0.47 1069995.0 69600.0 0.39 -0.055 -0.0898 3625027 CBKinase1_014132 Cc1sc2nc(SCC(=O)c3ccc(C)cc3)nc(O)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G15 compound treatment 788158.0 -118000.0 -0.65 971735.0 -28600.0 -0.16 -0.5707 -0.8575 3625028 CBKinase1_014133 FC(F)(F)c1cccc(NC(=O)CSc2nnc(c3ccccc3)c(n2)c4ccccc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G16 compound treatment 838005.0 -68400.0 -0.37 1078410.0 78000.0 0.44 0.0469 0.0813 3625029 CBKinase1_014134 Fc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2cc(Cl)ccc2Cl)C3CCCCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G17 compound treatment 822968.0 -83400.0 -0.46 1038939.0 38600.0 0.22 -0.1684 -0.3337 3625030 CBKinase1_014135 COC(=O)c1ccc(C)c(NC(=O)COc2ccccc2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G18 compound treatment 821836.0 -84600.0 -0.46 1087900.0 87500.0 0.49 0.0223 0.0331 3625031 CBKinase1_014136 COc1ccc(N(CC(=O)Nc2cccnc2)S(=O)(=O)C)c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G19 mock treatment 794697.0 -112000.0 -0.61 1046129.0 45800.0 0.26 -0.2489 -0.3759 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G20 mock treatment 838005.0 -68400.0 -0.37 1082790.0 82400.0 0.46 0.0644 0.108 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G21 compound treatment 791284.0 -115000.0 -0.63 1052539.0 52200.0 0.29 -0.2365 -0.3409 1353403 CBKinase1_014137 CCC(=O)Nc1cccc(NC(=O)COc2ccc3ccccc3c2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G22 compound treatment 785925.0 -120000.0 -0.66 1041088.0 40700.0 0.23 -0.3029 -0.4347 3625032 CBKinase1_014138 Cc1ccccc1OCC(=O)Nc2cccc(c3nc4cc(C)c(C)cc4o3)c2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G23 compound treatment 783676.0 -123000.0 -0.67 990933.0 -9440.0 -0.05 -0.5114 -0.7609 3625033 CBKinase1_014139 COc1ccccc1N(CC(=O)N2CCCCC2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 G24 compound treatment 789390.0 -117000.0 -0.64 994934.0 -5440.0 -0.03 -0.4734 -0.7402 3625034 CBKinase1_014140 CS(=O)(=O)N(CC(=O)Nc1ccc(cc1)C(=O)N)c2cc(Cl)cc(Cl)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H01 compound treatment 963474.0 57100.0 0.31 1011610.0 11200.0 0.06 0.2651 0.8338 1493798 CBKinase1_014141 CCc1ccc2oc(nc2c1)c3ccc(C)c(NC(=O)COc4ccc(Cl)cc4)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H02 compound treatment 954924.0 48500.0 0.26 1019477.0 19100.0 0.11 0.2634 0.9214 1552879 CBKinase1_014142 Cc1ccc(cc1)S(=O)(=O)NC(C)(C)C(=O)Oc2cc(C)c3c(c2)oc(=O)c4ccccc43 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H03 mock treatment 933246.0 26800.0 0.15 985249.0 -15100.0 -0.09 0.0433 0.2555 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H04 mock treatment 918791.0 12400.0 0.07 1034899.0 34500.0 0.19 0.1854 0.8999 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H05 compound treatment 930542.0 24100.0 0.13 981615.0 -18800.0 -0.11 0.0184 0.1088 1547858 CBKinase1_014143 COc1ccc(OCC(=O)Nc2cc(ccc2C)c3nc4ccccc4o3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H06 compound treatment 969769.0 63400.0 0.35 1024056.0 23700.0 0.13 0.339 0.9143 1217434 CBKinase1_014144 Cc1ccc(OCC(=O)Nc2nc(C)cc(C)n2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H07 compound treatment 939594.0 33200.0 0.18 1010277.0 9900.0 0.06 0.1676 0.884 3625035 CBKinase1_014145 [O-][N+](=O)c1ccc2oc(=O)c(cc2c1)C(=O)NCCCN3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H08 compound treatment 957315.0 50900.0 0.28 1040403.0 40000.0 0.23 0.356 0.9947 1236571 CBKinase1_014146 CC(C)c1ccc(C)cc1OCC(=O)Nc2ccccc2C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H09 compound treatment 1389938.0 484000.0 2.64 1276825.0 276000.0 1.56 2.9684 0.9684 1449958 CBKinase1_014147 Oc1cc(NC(=O)COc2ccc(Cl)cc2Cl)ccc1c3nc4ccccc4s3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H10 compound treatment 939048.0 32600.0 0.18 1068616.0 68200.0 0.38 0.398 0.9388 3625036 CBKinase1_014148 COc1ccc(C)cc1NC(=O)CN(C2CCCCC2)S(=O)(=O)c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H11 compound treatment 1005282.0 98900.0 0.54 1038274.0 37900.0 0.21 0.5327 0.9177 1474117 CBKinase1_014149 Cc1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4cccnc4)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H12 compound treatment 978010.0 71600.0 0.39 974465.0 -25900.0 -0.15 0.1731 0.4149 1579378 CBKinase1_014150 Cc1cc(C)c(cc1C)S(=O)(=O)NCc2ccccn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H13 compound treatment 893977.0 -12400.0 -0.07 972169.0 -28200.0 -0.16 -0.1604 -0.928 3625037 CBKinase1_014151 [O-][N+](=O)c1ccc2nc(CSc3ncnc4ccccc34)[nH]c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H14 compound treatment 914505.0 8090.0 0.04 974485.0 -25900.0 -0.15 -0.0719 -0.4719 1870589 CBKinase1_014152 Clc1ccc(C(=O)Nc2sc3CCCCc3c2C(=O)NCc4ccco4)c(Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H15 compound treatment 913760.0 7350.0 0.04 1009721.0 9350.0 0.05 0.0656 0.9909 1238501 CBKinase1_014153 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2nccs2)C3CN(C(=O)C3)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H16 compound treatment 909426.0 3010.0 0.02 1006457.0 6080.0 0.03 0.0359 0.9433 3625038 CBKinase1_014154 CCOc1cccc(c1)c2nnc(SCC(=O)Nc3c(C)cccc3C)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H17 compound treatment 967337.0 60900.0 0.33 1016104.0 15700.0 0.09 0.2979 0.8654 3625039 CBKinase1_014155 CCCCn1cc(SCC(=O)O)c2ccccc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H18 compound treatment 928590.0 22200.0 0.12 1025469.0 25100.0 0.14 0.1856 0.997 3625040 CBKinase1_014156 COc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(C)c3C)o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H19 mock treatment 883739.0 -22700.0 -0.12 1041654.0 41300.0 0.23 0.077 0.2921 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H20 mock treatment 907411.0 996.0 0.01 1014832.0 14500.0 0.08 0.0615 0.7526 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H21 compound treatment 913565.0 7150.0 0.04 969121.0 -31300.0 -0.18 -0.0969 -0.5374 3625041 CBKinase1_014157 COc1ccc(cc1)c2cc(=O)[nH]c(SCC(=O)Nc3ccc(Br)cc3)n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H22 compound treatment 925352.0 18900.0 0.1 929562.0 -70800.0 -0.4 -0.2091 -0.5072 3625042 CBKinase1_014158 Cc1ccc2nc(SCC(=O)NCc3ccccc3)[nH]c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H23 compound treatment 928095.0 21700.0 0.12 1020601.0 20200.0 0.11 0.1643 0.9998 1255251 CBKinase1_014159 CCOC(=O)c1cnc2c(C)cc(Cl)cc2c1NCCN3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 H24 compound treatment 933751.0 27300.0 0.15 1012957.0 12600.0 0.07 0.1557 0.9422 1870461 CBKinase1_014160 COc1ccc(cc1OC)C(=O)Nc2sc3CCCCc3c2C(=O)NC4CCS(=O)(=O)C4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I01 compound treatment 1063739.0 157000.0 0.86 1128039.0 128000.0 0.72 1.1162 0.9961 3625043 CBKinase1_014161 Cc1sc2ncnc(SCC(=O)c3ccc(Cl)cc3)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I02 compound treatment 994556.0 88100.0 0.48 1086333.0 86000.0 0.48 0.6829 1.0 1447604 CBKinase1_014162 CCC(=O)Nc1cccc(NC(=O)COc2c(C)cc(C)cc2Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I03 compound treatment 964774.0 58400.0 0.32 1125781.0 125000.0 0.71 0.7251 0.9352 3625044 CBKinase1_014163 O=C(Nc1sc2CCCCc2c1C#N)c3cc(cs3)S(=O)(=O)N4CCOCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I04 compound treatment 1006701.0 100000.0 0.55 1126192.0 126000.0 0.71 0.8886 0.9918 1299578 CBKinase1_014164 COc1ccc(NC(=O)CN2c3cccc4cccc(c34)S2(=O)=O)c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I05 mock treatment 999631.0 93200.0 0.51 1118713.0 118000.0 0.67 0.8315 0.9911 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I06 mock treatment 991794.0 85400.0 0.47 1136505.0 136000.0 0.77 0.8722 0.9715 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I07 compound treatment 992493.0 86100.0 0.47 1218633.0 218000.0 1.23 1.2022 0.9129 1217388 CBKinase1_014165 CN(C)CCCN1C(C(=C(O)C1=O)C(=O)c2cccs2)c3ccc(Cl)c(Cl)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I08 compound treatment 1017153.0 111000.0 0.6 1150724.0 150000.0 0.85 1.0267 0.9863 3625045 CBKinase1_014166 Cc1ccc(o1)C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c4ccc(Cl)c(Cl)c4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I09 compound treatment 980314.0 73900.0 0.4 1163020.0 163000.0 0.92 0.9335 0.932 1974790 CBKinase1_014167 COc1ccc(cc1[N+](=O)[O-])C(=O)CC2(O)C(=O)N(C)c3ccccc32 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I10 compound treatment 1003162.0 96700.0 0.53 1141329.0 141000.0 0.79 0.9353 0.9803 1651040 CBKinase1_014168 O=S(=O)(NC1C(Sc2ncccn2)c3cccc4cccc1c34)c5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I11 compound treatment 1031270.0 125000.0 0.68 1158557.0 158000.0 0.89 1.1125 0.9912 2067895 CBKinase1_014169 Cc1sc2nc(SCc3cc(O)[nH]n3)nc(N)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I12 compound treatment 1035352.0 129000.0 0.7 1103271.0 103000.0 0.58 0.9079 0.9954 3625046 CBKinase1_014170 CCOC(=O)c1c(NC(=O)c2ccccc2[N+](=O)[O-])scc1c3ccc(OC)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I13 compound treatment 1004016.0 97600.0 0.53 1146432.0 146000.0 0.82 0.9589 0.9778 1200805 CBKinase1_014171 COc1ccccc1NC(=S)NCc2cccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I14 compound treatment 974072.0 67700.0 0.37 1158491.0 158000.0 0.89 0.8914 0.924 2067817 CBKinase1_014172 Cc1ccc(cc1)S(=O)(=O)NCCSc2nncn2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I15 compound treatment 1010054.0 104000.0 0.57 1133720.0 133000.0 0.75 0.9316 0.9902 3625047 CBKinase1_014173 COc1ccc(cc1)S(=O)(=O)N(C)CCc2ccccn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I16 compound treatment 963998.0 57600.0 0.31 1140157.0 140000.0 0.79 0.7794 0.9188 3625048 CBKinase1_014174 COc1ccc(NC(=O)CN(c2ccc(Cl)cc2)S(=O)(=O)C)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I17 compound treatment 995107.0 88700.0 0.48 1097422.0 97000.0 0.55 0.7292 0.9982 3625049 CBKinase1_014175 CC(O)c1nc2ccccc2n1CCCOc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I18 compound treatment 999018.0 92600.0 0.51 1156609.0 156000.0 0.88 0.9802 0.9653 3625050 CBKinase1_014176 COc1cccc(c1)N(CC(=O)Nc2cccc(Cl)c2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I19 compound treatment 971827.0 65400.0 0.36 1108843.0 108000.0 0.61 0.6848 0.9672 3625051 CBKinase1_014177 CS(=O)(=O)N(CC(=O)NC1CC1)c2ccc(Cl)c(Cl)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I20 compound treatment 957804.0 51400.0 0.28 1039688.0 39300.0 0.22 0.3551 0.9932 3625052 CBKinase1_014178 Cc1c(Cl)cccc1NC(=O)CN(c2ccccc2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I21 mock treatment 947920.0 41500.0 0.23 1123753.0 123000.0 0.7 0.652 0.8914 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I22 mock treatment 938347.0 31900.0 0.17 1105928.0 106000.0 0.59 0.544 0.8774 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I23 compound treatment 945553.0 39100.0 0.21 1058214.0 57800.0 0.33 0.3816 0.979 3625053 CBKinase1_014179 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc(Cl)c(c2)c3nc4ccccc4s3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 I24 compound treatment 963887.0 57500.0 0.31 1092054.0 91700.0 0.52 0.5873 0.9714 3625054 CBKinase1_014180 CS(=O)(=O)N(CC(=O)Nc1ccccc1C(=O)O)c2cccc(c2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J01 compound treatment 946110.0 39700.0 0.22 950504.0 -49900.0 -0.28 -0.0455 -0.1282 1946624 CBKinase1_014181 Cc1cccc(c1)c2nc3cc(NC(=O)COc4ccc(cc4)[N+](=O)[O-])ccc3o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J02 compound treatment 1139769.0 233000.0 1.27 1100174.0 99800.0 0.56 1.2986 0.9325 3625055 CBKinase1_014182 FC(F)(F)c1ccccc1NC(=O)CSc2nc3CCCc3cc2C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J03 compound treatment 957263.0 50800.0 0.28 987789.0 -12600.0 -0.07 0.1461 0.5101 1927181 CBKinase1_014183 [O-][N+](=O)c1ccccc1OCC(=O)Nc2ccc3oc(nc3c2)c4cc(Br)ccc4Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J04 compound treatment 976231.0 69800.0 0.38 999382.0 -990.0 -0.01 0.2656 0.6967 3625056 CBKinase1_014184 Cc1c(OC(=O)[C@H](NC(=O)OC(C)(C)C)c2ccccc2)ccc3c4ccccc4c(=O)oc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J05 mock treatment 983287.0 76900.0 0.42 1037326.0 37000.0 0.21 0.444 0.9477 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J06 mock treatment 1011041.0 105000.0 0.57 999711.0 -661.0 0.0 0.4013 0.7025 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J07 compound treatment 1032027.0 126000.0 0.69 1096946.0 96600.0 0.54 0.8698 0.9935 1311725 CBKinase1_014185 Cc1cc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccncc4)cc(C)c1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J08 compound treatment 966803.0 60400.0 0.33 1093525.0 93200.0 0.53 0.6044 0.9749 3625058 CBKinase1_014186 Cc1sc2ncnc(SCC(=O)Nc3ccc(C)cc3)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J09 compound treatment 1010048.0 104000.0 0.57 1003745.0 3370.0 0.02 0.4135 0.7305 1931537 CBKinase1_014187 Cc1cccc(c1)c2nc3cc(NC(=O)COc4ccccc4[N+](=O)[O-])ccc3o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J10 compound treatment 942425.0 36000.0 0.2 1051644.0 51300.0 0.29 0.3434 0.9824 1594051 CBKinase1_014188 Cc1cccnc1NCC(O)COc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J11 compound treatment 947620.0 41200.0 0.22 1055392.0 55000.0 0.31 0.3784 0.9876 1434771 CBKinase1_014189 CC(C)c1ccc(C)cc1OCC(=O)Nc2cc(ccc2C)c3nc4ccccc4o3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J12 compound treatment 995777.0 89400.0 0.49 1015476.0 15100.0 0.09 0.4052 0.8181 3625059 CBKinase1_014190 Cc1cc(OCC(=O)Nc2ccccc2C(=O)N)cc(C)c1Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J13 compound treatment 950461.0 44000.0 0.24 1011549.0 11200.0 0.06 0.2146 0.8632 1486128 CBKinase1_014191 Cc1ccc(cc1NC(=O)COc2ccc(Cl)c(C)c2)c3nc4ncccc4o3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J14 compound treatment 1033832.0 127000.0 0.7 1065653.0 65300.0 0.37 0.7521 0.9557 3625060 CBKinase1_014192 Brc1ccc(NC(=O)c2c(NC(=O)CN3CCCC3)sc4CCCc24)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J15 compound treatment 887156.0 -19300.0 -0.11 1072653.0 72300.0 0.41 0.2137 0.508 3625061 CBKinase1_014193 [O-][N+](=O)c1ccccc1S(=O)CC(=O)Nc2cccc(c2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J16 compound treatment 1022054.0 116000.0 0.63 1087400.0 87000.0 0.49 0.7933 0.9922 3625062 CBKinase1_014194 CCNC(=O)c1c(NC(=O)COc2ccc(Cl)cc2Cl)sc3CCCCc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J17 compound treatment 996386.0 90000.0 0.49 1023095.0 22700.0 0.13 0.4379 0.8626 3625063 CBKinase1_014195 Cc1ccc(NC(=O)c2cccc(NC(=O)CCC(=O)O)c2)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J18 compound treatment 987255.0 80800.0 0.44 1073936.0 73600.0 0.41 0.6053 0.9995 3625064 CBKinase1_014196 COc1cc2c(cc1NC(=O)COc3ccc(Br)cc3C)oc4ccccc42 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J19 compound treatment 941222.0 34800.0 0.19 1054073.0 53700.0 0.3 0.3484 0.9748 1882036 CBKinase1_014197 Clc1ccc(Cl)c(c1)S(=O)(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J20 compound treatment 954622.0 48200.0 0.26 1072750.0 72400.0 0.41 0.4746 0.9775 3625065 CBKinase1_014198 Cc1ccc(NC(=O)c2c(NC(=O)CN3CCOCC3)sc4CCCc24)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J21 mock treatment 991652.0 85200.0 0.47 946235.0 -54100.0 -0.31 0.1133 0.2036 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J22 mock treatment 947619.0 41200.0 0.22 1013383.0 13000.0 0.07 0.2109 0.8914 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J23 compound treatment 940886.0 34500.0 0.19 953943.0 -46400.0 -0.26 -0.052 -0.1612 3625066 CBKinase1_014199 [O-][N+](=O)c1ccccc1NC(=O)CCCN2C(=O)c3cccc4cccc(C2=O)c34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 J24 compound treatment 921521.0 15100.0 0.08 1168142.0 168000.0 0.95 0.727 0.7659 3625067 CBKinase1_014200 COc1ccc(cc1C)C(Nc2ccccn2)c3ccc4ccc(C)nc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K01 compound treatment 958486.0 52100.0 0.28 1138130.0 138000.0 0.78 0.7501 0.9071 1138109 CBKinase1_014201 Cc1ccc(cc1NC(=O)COc2ccc(cc2)C3CCCCC3)c4nc5ncccc5o4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K02 compound treatment 885253.0 -21200.0 -0.12 1025876.0 25500.0 0.14 0.02 0.1082 1523615 CBKinase1_014202 Cc1ccc(OCC(=O)Nc2cccc(NC(=O)c3ccco3)c2)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K03 compound treatment 857661.0 -48800.0 -0.27 1049349.0 49000.0 0.28 0.007 0.0182 1250263 CBKinase1_014203 Cc1ccc(CC(CC(=O)O)C(=O)Nc2ccc(Cl)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K04 compound treatment 879188.0 -27200.0 -0.15 1040501.0 40100.0 0.23 0.0548 0.2026 3625068 CBKinase1_014204 CCOC(=O)CC(c1ccccc1)S(=O)(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K05 compound treatment 898558.0 -7860.0 -0.04 1049734.0 49400.0 0.28 0.1664 0.5911 1342712 CBKinase1_014205 COc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3cc(C)on3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K06 compound treatment 851527.0 -54900.0 -0.3 1017705.0 17300.0 0.1 -0.1428 -0.4531 1619331 CBKinase1_014206 Cc1ccc2oc(nc2c1)c3ccc(Cl)c(NC(=O)COc4ccc(Br)cc4)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K07 mock treatment 806485.0 -99900.0 -0.55 1044973.0 44600.0 0.25 -0.208 -0.3463 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K08 mock treatment 957892.0 51500.0 0.28 973637.0 -26700.0 -0.15 0.0922 0.289 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K09 compound treatment 856691.0 -49700.0 -0.27 1021171.0 20800.0 0.12 -0.1091 -0.3688 3625069 CBKinase1_014207 Cc1sc2ncnc(SCC(=O)c3cc(Cl)sc3Cl)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K10 compound treatment 908989.0 2570.0 0.01 993853.0 -6520.0 -0.04 -0.016 -0.4078 1788959 CBKinase1_014208 CCCCn1c(SCC(=O)N)nc2n(C)c(=O)n(C)c(=O)c12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K11 compound treatment 865233.0 -41200.0 -0.22 1028168.0 27800.0 0.16 -0.0482 -0.1759 1548608 CBKinase1_014209 Cc1sc2nc(SCC(=O)O)n(c3ccc(Cl)c(Cl)c3)c(=O)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K12 compound treatment 870314.0 -36100.0 -0.2 983402.0 -17000.0 -0.1 -0.207 -0.9449 1740749 CBKinase1_014210 Cc1ccc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc4OCCOc4c3)cc2)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K13 compound treatment 802440.0 -104000.0 -0.57 1025310.0 24900.0 0.14 -0.302 -0.5164 1870596 CBKinase1_014211 COc1ccccc1OC(C)C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K14 compound treatment 875665.0 -30700.0 -0.17 1041703.0 41300.0 0.23 0.046 0.1603 1640250 CBKinase1_014212 Cc1ccccc1C(=O)Nc2ccc(OCC(=O)O)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K15 mock treatment 881882.0 -24500.0 -0.13 847857.0 -153000.0 -0.86 -0.7026 -0.8075 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K16 mock treatment 801677.0 -105000.0 -0.57 1067129.0 66800.0 0.38 -0.1383 -0.202 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K17 compound treatment 886625.0 -19800.0 -0.11 1007217.0 6840.0 0.04 -0.0491 -0.4281 1479863 CBKinase1_014213 Cc1cc(C)cc(OCC(=O)Nc2cc(ccc2C)c3nc4ccccc4s3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K18 compound treatment 859638.0 -46800.0 -0.26 1017819.0 17400.0 0.1 -0.111 -0.4058 3625070 CBKinase1_014214 COc1ccc(cc1Cl)N(CC(=O)Nc2cc(C)ccc2OC)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K19 compound treatment 892831.0 -13600.0 -0.07 848168.0 -152000.0 -0.86 -0.6591 -0.7654 3625071 CBKinase1_014215 [O-][N+](=O)c1ccc(Oc2ccc(cc2)C(=O)Cn3nnc4ccccc34)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K20 compound treatment 874416.0 -32000.0 -0.17 1043587.0 43200.0 0.24 0.0487 0.1625 3625072 CBKinase1_014216 COc1ccc(Cl)cc1N(CC(=O)Nc2cc(Cl)ccc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K21 compound treatment 766531.0 -140000.0 -0.76 1041457.0 41100.0 0.23 -0.3763 -0.4715 1180369 CBKinase1_014217 Nc1nnc(SCc2nc3ccccc3n2Cc4ccccc4)s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K22 compound treatment 858818.0 -47600.0 -0.26 1001290.0 918.0 0.01 -0.1801 -0.6929 3625073 CBKinase1_014218 CS(=O)(=O)N(CC(=O)Nc1ccccc1C(=O)O)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K23 mock treatment 660745.0 -246000.0 -1.34 852021.0 -148000.0 -0.84 -1.5397 -0.9741 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 K24 mock treatment 930599.0 24200.0 0.13 1014999.0 14600.0 0.08 0.1517 0.9743 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L01 compound treatment 784774.0 -122000.0 -0.66 950675.0 -49700.0 -0.28 -0.6677 -0.9263 1946958 CBKinase1_014219 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc(cc2)c3nc4ccccc4o3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L02 compound treatment 967111.0 60700.0 0.33 956281.0 -44100.0 -0.25 0.0586 0.1414 1211831 CBKinase1_014220 Cc1ccc(OCC(=O)NC(=S)Nc2cc(ccc2C)C(=O)O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L03 compound treatment 1110533.0 204000.0 1.11 1097514.0 97100.0 0.55 1.1752 0.9465 1685088 CBKinase1_014221 Oc1ccc(NC(=O)COc2ccc(Cl)cc2Cl)cc1c3nc4ccccc4s3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L04 compound treatment 961992.0 55600.0 0.3 952193.0 -48200.0 -0.27 0.0225 0.0553 1867365 CBKinase1_014222 COc1ccc(OC)c(NC(=O)C2=C(C)NC(=O)NC2c3cccc(OC)c3OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L05 compound treatment 1003453.0 97000.0 0.53 1052328.0 52000.0 0.29 0.5817 0.9609 1154463 CBKinase1_014223 Cc1ccc2oc(nc2c1)c3cccc(NC(=O)COc4ccc(Cl)cc4)c3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L06 compound treatment 992324.0 85900.0 0.47 1020186.0 19800.0 0.11 0.4106 0.8517 1361741 CBKinase1_014224 Cc1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccc(F)cc4Cl)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L07 mock treatment 948908.0 42500.0 0.23 1008337.0 7960.0 0.04 0.1958 0.8286 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L08 mock treatment 1063512.0 157000.0 0.86 1041327.0 41000.0 0.23 0.7697 0.8666 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L09 compound treatment 965020.0 58600.0 0.32 968582.0 -31800.0 -0.18 0.0995 0.2714 1588639 CBKinase1_014225 Cc1ccc(cc1NC(=O)COc2cc(C)c(Cl)c(C)c2)c3nc4ncccc4o3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L10 compound treatment 959077.0 52700.0 0.29 1016169.0 15800.0 0.09 0.2663 0.8846 1862851 CBKinase1_014226 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccc(F)cc4Cl)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L11 compound treatment 957120.0 50700.0 0.28 993647.0 -6730.0 -0.04 0.1689 0.6046 1225211 CBKinase1_014227 CN(C)c1nc(Nc2nc3ccccc3[nH]2)nc(n1)N(C)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L12 compound treatment 994987.0 88600.0 0.48 1081582.0 81200.0 0.46 0.6656 0.9996 3625074 CBKinase1_014228 COc1ccc(OC)c(NC(=O)c2c(NC(=O)CN3CCCC(C)C3)sc4CCCc24)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L13 compound treatment 913909.0 7490.0 0.04 942455.0 -57900.0 -0.33 -0.2019 -0.6137 3625075 CBKinase1_014229 COc1ccccc1NC(=O)CCC(=O)c2ccc(C)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L14 compound treatment 856707.0 -49700.0 -0.27 984183.0 -16200.0 -0.09 -0.2564 -0.8956 3625076 CBKinase1_014230 CCN(CC)CC(=O)Nc1sc2CCCc2c1C(=O)Nc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L15 mock treatment 929023.0 22600.0 0.12 1089717.0 89300.0 0.5 0.4434 0.8551 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L16 mock treatment 937753.0 31300.0 0.17 903464.0 -96900.0 -0.55 -0.2653 -0.4634 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L17 compound treatment 954446.0 48000.0 0.26 970792.0 -29600.0 -0.17 0.0675 0.2173 3625077 CBKinase1_014231 Ic1cccc(c1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L18 compound treatment 894997.0 -11400.0 -0.06 958598.0 -41800.0 -0.24 -0.2106 -0.8645 3625078 CBKinase1_014232 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2sc3CCCCc3c2C(=O)NCc4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L19 compound treatment 989498.0 83100.0 0.45 943935.0 -56400.0 -0.32 0.0958 0.1729 3625079 CBKinase1_014233 COc1ccccc1N(CC(=O)N(C)C)S(=O)(=O)c2ccc(C)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L20 compound treatment 1062540.0 156000.0 0.85 1068561.0 68200.0 0.38 0.8745 0.9353 3625080 CBKinase1_014234 Cc1ccc(cc1S(=O)(=O)NCCOc2ccc(Cl)cc2C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L21 compound treatment 1087935.0 182000.0 0.99 1087366.0 87000.0 0.49 1.0475 0.9474 1371218 CBKinase1_014235 COC(=O)c1cc(COc2ccc3c(c2)oc(=O)c4ccccc43)c(C)o1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L22 compound treatment 963423.0 57000.0 0.31 1046082.0 45700.0 0.26 0.4023 0.9956 3625081 CBKinase1_014236 Cc1ccc(NC(=O)COc2cc(C)c(Br)c(C)c2)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L23 mock treatment 891218.0 -15200.0 -0.08 971131.0 -29200.0 -0.16 -0.1752 -0.9495 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 L24 mock treatment 962338.0 55900.0 0.31 1087642.0 87300.0 0.49 0.5637 0.9737 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M01 compound treatment 963915.0 57500.0 0.31 1278994.0 279000.0 1.57 1.3324 0.832 3625082 CBKinase1_014237 Cc1ccc(CC(CC(=O)O)C(=O)Nc2cc(C)ccc2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M02 compound treatment 917344.0 10900.0 0.06 1124991.0 125000.0 0.7 0.5389 0.7644 3625083 CBKinase1_014238 CC(O)c1cccc(NC(=O)C2C(C3CC2C=C3)C(=O)O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M03 compound treatment 911979.0 5560.0 0.03 1132625.0 132000.0 0.75 0.5486 0.7353 1676366 CBKinase1_014239 Cc1nn(Cc2ccccc2)c(C)c1CCC(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M04 compound treatment 892349.0 -14100.0 -0.08 1090118.0 89700.0 0.51 0.3034 0.593 1337445 CBKinase1_014240 Cc1ccc2oc(nc2c1)c3cccc(NC(=O)COc4cccc(C)c4C)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M05 compound treatment 874069.0 -32300.0 -0.18 1060592.0 60200.0 0.34 0.1151 0.3009 3625084 CBKinase1_014241 Cc1ccc(cc1NS(=O)(=O)c2cccc(c2)C(=O)Nc3ccccc3)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M06 compound treatment 968882.0 62500.0 0.34 1137247.0 137000.0 0.77 0.7867 0.9326 3625085 CBKinase1_014242 COc1ccc(cc1)S(=O)(=O)N(CC(=O)O)c2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M07 compound treatment 917334.0 10900.0 0.06 1053088.0 52700.0 0.3 0.2523 0.8324 3625086 CBKinase1_014243 COc1ccc(cc1)C(=O)CSc2ncnc3sc4CCCCc4c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M08 compound treatment 900046.0 -6370.0 -0.03 1031336.0 31000.0 0.17 0.0988 0.5553 3625087 CBKinase1_014244 CS(=O)(=O)N(CC(=O)Nc1ccc(F)cc1)c2ccc(Cl)c(Cl)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M09 mock treatment 1051999.0 146000.0 0.79 1099053.0 98700.0 0.56 0.9553 0.9848 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M10 mock treatment 906577.0 162.0 0.0 1053829.0 53500.0 0.3 0.2137 0.7092 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M11 compound treatment 917816.0 11400.0 0.06 1223183.0 223000.0 1.26 0.932 0.7412 1623187 CBKinase1_014245 Cc1ccc(cc1)S(=O)(=O)CC(CN2CCOCC2)N3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M12 compound treatment 949367.0 43000.0 0.23 1079750.0 79400.0 0.45 0.4822 0.9546 1253932 CBKinase1_014246 CCc1ccc2oc(nc2c1)c3cc(NC(=O)COc4ccc(OC)cc4)ccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M13 mock treatment 989303.0 82900.0 0.45 1090025.0 89700.0 0.51 0.6773 0.9985 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M14 mock treatment 953983.0 47600.0 0.26 1073232.0 72900.0 0.41 0.474 0.9756 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M15 compound treatment 950480.0 44100.0 0.24 1077689.0 77300.0 0.44 0.4783 0.9608 1506908 CBKinase1_014247 Cc1ccc(C)c(OCC(=O)Nc2ccccc2C#N)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M16 compound treatment 951427.0 45000.0 0.25 1027980.0 27600.0 0.16 0.2838 0.9757 3625088 CBKinase1_014248 COc1ccc(C)cc1NC(=O)CN(c2cc(Cl)ccc2OC)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M17 compound treatment 935991.0 29600.0 0.16 1101257.0 101000.0 0.57 0.5163 0.8734 1206057 CBKinase1_014249 Cc1cc(C)c(OCC(=O)Nc2cccc(NC(=O)c3ccco3)c2)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M18 compound treatment 922169.0 15800.0 0.09 1111795.0 111000.0 0.63 0.5049 0.7965 3625089 CBKinase1_014250 Cc1cc(NC(=O)CN(c2ccc(Cl)cc2)S(=O)(=O)C)ccc1Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M19 compound treatment 1028582.0 122000.0 0.67 1157280.0 157000.0 0.88 1.097 0.9903 1740660 CBKinase1_014251 Cc1cccc(OCC(=O)Nc2cccc(c3nc4cc(Cl)ccc4o3)c2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M20 compound treatment 956438.0 50000.0 0.27 1179031.0 179000.0 1.01 0.9052 0.8675 3625090 CBKinase1_014252 COc1ccc(cc1)N(CC(=O)Nc2cc(Cl)ccc2OC)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M21 compound treatment 1030523.0 124000.0 0.68 1059395.0 59000.0 0.33 0.7144 0.9464 3625091 CBKinase1_014253 COCCNC(=O)c1c(NC(=O)c2ccccc2C)sc3CCCCc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M22 compound treatment 956727.0 50300.0 0.27 1127848.0 127000.0 0.72 0.7023 0.913 3625092 CBKinase1_014254 CS(=O)(=O)N(CC(=O)Nc1ccccc1C(=O)O)c2cccc(Cl)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M23 compound treatment 918166.0 11800.0 0.06 1934141.0 934000.0 5.26 3.7669 0.7157 1319491 CBKinase1_014255 Cc1c(NC(=O)COc2cc(Cl)c(Cl)cc2Cl)cccc1c3nc4ccccc4o3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 M24 compound treatment 1006781.0 100000.0 0.55 1143852.0 143000.0 0.81 0.9593 0.982 1381135 CBKinase1_014256 Cc1cccc(OCC(=O)Nc2cccc(c2)c3nc4cc(C)cc(C)c4o3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N01 compound treatment 897695.0 -8720.0 -0.05 924662.0 -75700.0 -0.43 -0.3354 -0.7811 1132630 CBKinase1_014257 Cc1cc(OCC(=O)Nc2cccnc2)cc(C)c1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N02 compound treatment 913825.0 7410.0 0.04 914274.0 -86100.0 -0.49 -0.3145 -0.6459 1439323 CBKinase1_014258 COc1cc(C)c(cc1C)S(=O)(=O)NCc2cccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N03 compound treatment 878334.0 -28100.0 -0.15 975240.0 -25100.0 -0.14 -0.2086 -0.9992 1946808 CBKinase1_014259 Oc1ccc(NC(=O)COc2ccccc2[N+](=O)[O-])cc1c3nc4ccccc4s3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N04 compound treatment 935339.0 28900.0 0.16 1001082.0 710.0 0.0 0.1145 0.7248 1872915 CBKinase1_014260 CN(C(=O)C)c1ccc(NC(=O)COc2ccc(cc2)[N+](=O)[O-])cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N05 compound treatment 902940.0 -3470.0 -0.02 991770.0 -8600.0 -0.05 -0.0477 -0.9161 1946827 CBKinase1_014261 [O-][N+](=O)c1ccccc1OCC(=O)Nc2ccc(cc2)c3nc4cc(Cl)ccc4o3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N06 compound treatment 1006587.0 100000.0 0.55 1052691.0 52300.0 0.29 0.5952 0.958 3625093 CBKinase1_014262 O=C(CN1CCCCC1)Nc2nonc2NC(=O)CN3CCCCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N07 compound treatment 965177.0 58800.0 0.32 1003145.0 2770.0 0.02 0.2379 0.7407 1928842 CBKinase1_014263 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)COc4ccc(cc4)[N+](=O)[O-])cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N08 compound treatment 965848.0 59400.0 0.32 1083890.0 83500.0 0.47 0.5623 0.9835 1351144 CBKinase1_014264 CCc1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccc(OC)cc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N09 mock treatment 941410.0 35000.0 0.19 1021869.0 21500.0 0.12 0.2208 0.9758 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N10 mock treatment 986347.0 79900.0 0.44 1076445.0 76100.0 0.43 0.6118 1.0 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N11 compound treatment 956089.0 49700.0 0.27 1037114.0 36700.0 0.21 0.3382 0.9911 1590784 CBKinase1_014265 Oc1ccc(NC(=O)Cn2nc(c3ccccc3)c4ccccc4c2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N12 compound treatment 885483.0 -20900.0 -0.11 1018423.0 18100.0 0.1 -0.0089 -0.0579 3625094 CBKinase1_014266 Clc1ccc(NC(=O)c2c(NC(=O)CN3CCCCC3)sc4CCCc24)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N13 mock treatment 1009753.0 103000.0 0.56 1048421.0 48000.0 0.27 0.5904 0.9435 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N14 mock treatment 913427.0 7010.0 0.04 1000636.0 264.0 0.0 0.0281 0.734 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N15 compound treatment 1033052.0 127000.0 0.69 1068230.0 67900.0 0.38 0.7593 0.961 3625095 CBKinase1_014267 COC(=O)c1ccc(C)c(NC(=O)CN(c2ccc(F)cc2)S(=O)(=O)C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N16 compound treatment 1033921.0 128000.0 0.7 1018376.0 18000.0 0.1 0.564 0.8017 3625096 CBKinase1_014268 COC(=O)c1ccccc1NC(=O)COc2cc(C)c(Br)c(C)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N17 compound treatment 940692.0 34300.0 0.19 1030589.0 30200.0 0.17 0.2528 0.9989 3625097 CBKinase1_014269 OC(CON1C(=O)c2ccccc2C1=O)COc3ccc(cc3)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N18 compound treatment 1035990.0 130000.0 0.71 1162201.0 162000.0 0.91 1.1452 0.9921 1875316 CBKinase1_014270 Cc1ccc(cc1)C(=O)Nc2sc3CCCCc3c2C(=O)NCc4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N19 compound treatment 954304.0 47900.0 0.26 1125703.0 125000.0 0.71 0.6844 0.9086 3625098 CBKinase1_014271 Clc1ccc(Cl)c(c1)S(=O)(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N20 compound treatment 985716.0 79300.0 0.43 1045137.0 44800.0 0.25 0.4846 0.967 3625099 CBKinase1_014272 COc1ccc(NC(=O)COc2ccc(Br)cc2C)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N21 compound treatment 985599.0 79200.0 0.43 1060055.0 59700.0 0.34 0.5436 0.9923 1234345 CBKinase1_014273 CC(C)(C)c1ccc(OCC(O)Cn2cnc3ccccc23)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N22 compound treatment 999628.0 93200.0 0.51 1183198.0 183000.0 1.03 1.0885 0.9471 3625100 CBKinase1_014274 COc1ccc(NC(=O)COc2cc(C)c(Br)c(C)c2)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N23 compound treatment 1011299.0 105000.0 0.57 1082113.0 81700.0 0.46 0.7307 0.9942 3625101 CBKinase1_014275 [O-][N+](=O)c1ccccc1NC(=O)COc2cc(Cl)c(Cl)cc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 N24 compound treatment 934691.0 28300.0 0.15 932924.0 -67400.0 -0.38 -0.1597 -0.3891 1874014 CBKinase1_014276 Clc1c(sc2ccccc12)C(=O)Nc3sc4CCCCc4c3C(=O)NCc5ccco5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O01 compound treatment 857984.0 -48400.0 -0.26 1112858.0 112000.0 0.63 0.2614 0.3805 1181089 CBKinase1_014277 COc1ccc(cc1S(=O)(=O)NCc2ccco2)C(=O)Nc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O02 compound treatment 839695.0 -66700.0 -0.36 1064720.0 64300.0 0.36 -0.0011 -0.0022 3625102 CBKinase1_014278 CC(C)c1ccc2oc(nc2c1)c3ccc(NC(=O)COc4ccc(cc4)[N+](=O)[O-])cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O03 compound treatment 893463.0 -13000.0 -0.07 1073709.0 73300.0 0.41 0.2423 0.5778 3625103 CBKinase1_014279 CCOC(=O)c1c(NC(=O)C2COc3ccccc3O2)scc1c4ccc(C)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O04 compound treatment 952229.0 45800.0 0.25 1090135.0 89800.0 0.51 0.5346 0.9472 1411692 CBKinase1_014280 Cc1nnc(s1)N2C(C(=C(O)C2=O)C(=O)c3ccco3)c4cccc(Oc5ccccc5)c4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O05 compound treatment 883142.0 -23300.0 -0.13 1099919.0 99500.0 0.56 0.3069 0.5335 3625104 CBKinase1_014281 CCc1cc2c(SCC(=O)c3ccc(C)cc3)ncnc2s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O06 compound treatment 947718.0 41300.0 0.23 1124737.0 124000.0 0.7 0.6551 0.8897 3625105 CBKinase1_014282 Cc1cccc(N(CC(=O)Nc2ccc(F)cc2)S(=O)(=O)C)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O07 compound treatment 906862.0 447.0 0.0 1070172.0 69800.0 0.39 0.2799 0.7115 1620006 CBKinase1_014283 O=C(COc1ccc(cc1)C2CCCCC2)Nc3cccc(c3)c4nc5ncccc5o4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O08 compound treatment 910737.0 4320.0 0.02 1039201.0 38800.0 0.22 0.1714 0.7788 3625106 CBKinase1_014284 COc1cccc(c1)n2nnnc2SCC(=O)Nc3c(C)cc(C)cc3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O09 compound treatment 915389.0 8970.0 0.05 1058389.0 58000.0 0.33 0.2659 0.8041 3625107 CBKinase1_014285 COc1ccc(NC(=O)C2=C(C)NC(=S)NC2c3cccc(c3)[N+](=O)[O-])c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O10 compound treatment 885785.0 -20600.0 -0.11 994157.0 -6220.0 -0.04 -0.1044 -0.8852 1355571 CBKinase1_014286 Cc1cccc(OCC(=O)Nc2ccc(Cl)c(c2)c3nc4ccccc4o3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O11 mock treatment 844622.0 -61800.0 -0.34 1072711.0 72300.0 0.41 0.0498 0.094 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O12 mock treatment 867066.0 -39300.0 -0.21 939096.0 -61300.0 -0.35 -0.3961 -0.9739 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O13 compound treatment 904535.0 -1880.0 -0.01 1082347.0 82000.0 0.46 0.3195 0.6912 3625108 CBKinase1_014287 CC(=O)c1cccc(NS(=O)(=O)c2cccc(c2)S(=O)(=O)c3ccccc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O14 compound treatment 949458.0 43000.0 0.23 1079309.0 78900.0 0.44 0.4808 0.9555 1021944 CBKinase1_014288 OC(=O)CNC(=O)CN1C(=O)c2ccccc2C1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O15 compound treatment 889853.0 -16600.0 -0.09 1031217.0 30800.0 0.17 0.059 0.3011 1176559 CBKinase1_014289 Cc1ccc(OCC(=O)Nc2cccc(NC(=O)c3ccccc3)c2)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O16 compound treatment 857821.0 -48600.0 -0.27 1038652.0 38300.0 0.22 -0.035 -0.1024 3625109 CBKinase1_014290 COc1ccc(C)cc1NC(=O)CN(c2cc(C)cc(C)c2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O17 compound treatment 901174.0 -5240.0 -0.03 1046670.0 46300.0 0.26 0.1643 0.6258 1251082 CBKinase1_014291 Cc1ccc2oc(nc2c1)c3ccc(Cl)c(NC(=O)COc4ccc(C)c(C)c4)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O18 compound treatment 898060.0 -8350.0 -0.05 1068225.0 67900.0 0.38 0.2382 0.6184 3625110 CBKinase1_014292 COc1ccc(NC(=O)CN(c2cc(C)ccc2OC)S(=O)(=O)C)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O19 compound treatment 927552.0 21100.0 0.12 1183498.0 183000.0 1.03 0.8115 0.7813 3625111 CBKinase1_014293 COc1ccc(NC(=O)COc2ccccc2[N+](=O)[O-])cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O20 compound treatment 987129.0 80700.0 0.44 1122200.0 122000.0 0.69 0.7971 0.977 3625112 CBKinase1_014294 Cc1ccc(Cl)cc1NC(=O)CN(c2ccccc2F)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O21 compound treatment 676444.0 -230000.0 -1.26 712659.0 -288000.0 -1.62 -2.0345 -0.992 3625113 CBKinase1_014295 Cc1ccc(cc1NC(=O)CC2Nc3cc(C)c(C)cc3NC2=O)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O22 compound treatment 991730.0 85300.0 0.47 1088607.0 88200.0 0.5 0.681 0.9995 3625114 CBKinase1_014296 COc1ccc(cc1)N(CC(=O)Nc2ccccc2C(=O)O)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O23 compound treatment 891373.0 -15000.0 -0.08 1009860.0 9490.0 0.05 -0.0203 -0.2067 1872141 CBKinase1_014297 O=C(C(c1ccccc1)n2nnc3ccccc23)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 O24 compound treatment 894129.0 -12300.0 -0.07 1052950.0 52600.0 0.3 0.1621 0.5336 3625115 CBKinase1_014298 Cc1cccc(C)c1NC(=O)CN(C2CCCCC2)S(=O)(=O)c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P01 compound treatment 855384.0 -51000.0 -0.28 872595.0 -128000.0 -0.72 -0.7063 -0.9146 1929639 CBKinase1_014299 CCc1ccc(cc1)c2nc3cc(NC(=O)COc4ccccc4[N+](=O)[O-])ccc3o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P02 compound treatment 831071.0 -75300.0 -0.41 928945.0 -71400.0 -0.4 -0.5755 -0.9999 1862720 CBKinase1_014300 Cc1cc(C)nc(NC(=O)COc2ccc(cc2)[N+](=O)[O-])n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P03 compound treatment 829268.0 -77100.0 -0.42 915594.0 -84800.0 -0.48 -0.6357 -0.998 1946844 CBKinase1_014301 CCc1ccc(cc1)c2nc3cc(NC(=O)COc4ccc(cc4)[N+](=O)[O-])ccc3o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P04 compound treatment 934093.0 27700.0 0.15 973015.0 -27400.0 -0.15 -0.0022 -0.0101 1434542 CBKinase1_014302 Cc1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccccc4C)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P05 compound treatment 959314.0 52900.0 0.29 986441.0 -13900.0 -0.08 0.1487 0.4968 1652159 CBKinase1_014303 Oc1ccc(NC(=O)COc2ccc(Cl)cc2)cc1c3nc4ccccc4o3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P06 compound treatment 838104.0 -68300.0 -0.37 936173.0 -64200.0 -0.36 -0.5196 -0.9999 3625116 CBKinase1_014304 Cc1sc2nc(SCc3n[nH]c(=S)n3c4ccccc4)nc(N)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P07 compound treatment 984808.0 78400.0 0.43 1040516.0 40100.0 0.23 0.4626 0.9556 3625117 CBKinase1_014305 Cc1cccc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccncc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P08 compound treatment 996309.0 89900.0 0.49 1068860.0 68500.0 0.39 0.62 0.9929 3625118 CBKinase1_014306 FC(F)(F)c1ccccc1NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3cccs3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P09 compound treatment 906919.0 504.0 0.0 973239.0 -27100.0 -0.15 -0.1062 -0.6943 1927598 CBKinase1_014307 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccc(Br)cc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P10 compound treatment 925400.0 19000.0 0.1 1001884.0 1510.0 0.01 0.0793 0.7627 3625119 CBKinase1_014308 Cc1sc(NC(=O)C2CC(=CCC2C(=O)O)Cl)c(C#N)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P11 mock treatment 897043.0 -9370.0 -0.05 988894.0 -11500.0 -0.06 -0.0819 -0.9932 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P12 mock treatment 950817.0 44400.0 0.24 963172.0 -37200.0 -0.21 0.0232 0.0722 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P13 compound treatment 982228.0 75800.0 0.41 990539.0 -9830.0 -0.06 0.2535 0.607 3625120 CBKinase1_014309 CCOC(=O)c1c(NC(=O)c2ccc(o2)c3ccccc3[N+](=O)[O-])sc4CCCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P14 compound treatment 1004431.0 98000.0 0.54 945459.0 -54900.0 -0.31 0.1595 0.2581 3625121 CBKinase1_014310 CCNC(=O)c1c(NC(=O)COc2cccc3ccccc23)sc4CCCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P15 compound treatment 919509.0 13100.0 0.07 980354.0 -20000.0 -0.11 -0.0292 -0.2189 1173335 CBKinase1_014311 O=C(CSc1ncnc2[nH]cnc12)N3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P16 compound treatment 952658.0 46200.0 0.25 990734.0 -9640.0 -0.05 0.1401 0.5425 3625122 CBKinase1_014312 COc1cc(NC(=O)COc2ccccc2OC)cc(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P17 compound treatment 925633.0 19200.0 0.1 952578.0 -47800.0 -0.27 -0.1163 -0.4023 1285860 CBKinase1_014313 CC(=O)Oc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P18 compound treatment 920498.0 14100.0 0.08 991309.0 -9060.0 -0.05 0.0182 0.1977 3625123 CBKinase1_014314 Cc1cc(C)c(NC(=O)COc2ccccc2C(=O)Nc3ccc4c(c3)oc5ccccc54)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P19 compound treatment 928147.0 21700.0 0.12 1071437.0 71100.0 0.4 0.3671 0.8788 1140371 CBKinase1_014315 Cc1ccc(cc1)C(=O)CC2(O)C(=O)N(Cc3cccc4ccccc34)c5ccccc52 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P20 compound treatment 918108.0 11700.0 0.06 1039498.0 39100.0 0.22 0.2011 0.8758 3625124 CBKinase1_014316 CCOc1ccccc1NC(=O)CSc2nc3ccccc3c(=O)n2c4cccc(c4)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P21 compound treatment 927947.0 21500.0 0.12 1083411.0 83000.0 0.47 0.4141 0.8581 3625125 CBKinase1_014317 COc1ccc(OC)c(NC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P22 compound treatment 933700.0 27300.0 0.15 1063408.0 63000.0 0.36 0.3566 0.9255 3625126 CBKinase1_014318 Cc1ccc(OCCCn2cnc3ccccc3c2=O)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P23 compound treatment 888077.0 -18300.0 -0.1 1058892.0 58500.0 0.33 0.1624 0.4713 3625127 CBKinase1_014319 COc1ccc(NC(=O)CN(c2ccc(Cl)c(Cl)c2)S(=O)(=O)C)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2368 P24 compound treatment 864996.0 -41400.0 -0.23 1016139.0 15800.0 0.09 -0.0971 -0.3995 1875692 CBKinase1_014320 Cc1cc(C)c(c(C)c1)S(=O)(=O)NCCN2CCN(CC2)S(=O)(=O)c3c(C)cc(C)cc3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A01 compound treatment 799564.0 -55800.0 -0.3 802232.0 -136000.0 -0.77 -0.7589 -0.9179 3625128 CBKinase1_014321 CC(N(c1ccccc1)S(=O)(=O)C)C(=O)Nc2ccccc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A02 compound treatment 809549.0 -45800.0 -0.25 1092121.0 154000.0 0.87 0.435 0.483 1242039 CBKinase1_014322 Cc1cc(C)c(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4Cl)cc3s2)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A03 compound treatment 749098.0 -106000.0 -0.58 744967.0 -194000.0 -1.09 -1.182 -0.9563 1297655 CBKinase1_014323 Oc1ccccc1C(=O)CC2(O)C(=O)N(Cc3cccc4ccccc34)c5ccccc52 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A04 compound treatment 847412.0 -7940.0 -0.04 1070321.0 132000.0 0.74 0.4943 0.6647 3625129 CBKinase1_014324 CC(=O)c1cccc(NC(=O)CSc2nnc3c4ccccc4[nH]c3n2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A05 compound treatment 714606.0 -141000.0 -0.77 1002766.0 64200.0 0.36 -0.2877 -0.3387 3625130 CBKinase1_014325 CS(=O)(=O)NCCSCc1ccco1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A06 compound treatment 764181.0 -91200.0 -0.5 986299.0 47700.0 0.27 -0.1619 -0.2862 1219435 CBKinase1_014326 O=C(COc1ccccc1)Nc2nc[nH]n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A07 compound treatment 565425.0 -290000.0 -1.58 832817.0 -106000.0 -0.6 -1.5409 -0.911 1354198 CBKinase1_014327 OC1(CC(=O)c2ccc(F)cc2)C(=O)N(Cc3cccc4ccccc34)c5ccccc51 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A08 compound treatment 768118.0 -87200.0 -0.48 950672.0 12100.0 0.07 -0.2887 -0.6001 3625131 CBKinase1_014328 Fc1ccccc1n2nnnc2SCC(=O)Nc3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A09 compound treatment 748216.0 -107000.0 -0.58 902292.0 -36300.0 -0.2 -0.5584 -0.901 3625132 CBKinase1_014329 Clc1cccc(Cl)c1C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A10 compound treatment 679603.0 -176000.0 -0.96 936371.0 -2240.0 -0.01 -0.6874 -0.7164 3625133 CBKinase1_014330 Cc1sc2ncnc(SCC(=O)NCc3ccccc3)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A11 compound treatment 663770.0 -192000.0 -1.05 868413.0 -70200.0 -0.4 -1.0194 -0.9116 1658188 CBKinase1_014331 OC(=O)CSc1cn(Cc2ccccc2)c3ccccc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A12 compound treatment 828230.0 -27100.0 -0.15 777656.0 -161000.0 -0.91 -0.7462 -0.8118 1553477 CBKinase1_014332 COC(=O)c1sc(NC(=O)COc2ccc(cc2)C(C)C)c(C#N)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A13 mock treatment 887305.0 32000.0 0.17 995947.0 57300.0 0.32 0.3519 0.9581 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A14 mock treatment 887066.0 31700.0 0.17 935753.0 -2860.0 -0.02 0.111 0.6385 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A15 compound treatment 955386.0 100000.0 0.55 940869.0 2260.0 0.01 0.3952 0.7234 3625134 CBKinase1_014333 Cc1cccc(N(CC(=O)Nc2ccc(Cl)cc2)S(=O)(=O)C)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A16 compound treatment 926368.0 71000.0 0.39 985392.0 46800.0 0.26 0.4606 0.9823 3625135 CBKinase1_014334 CCOc1cc(ccc1NC(=O)CC2Sc3ccccc3NC2=O)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A17 compound treatment 964821.0 109000.0 0.6 1025492.0 86900.0 0.49 0.7689 0.9951 1682475 CBKinase1_014335 COc1ccc(NC(=O)CSc2nc(N)cc(=O)[nH]2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A18 compound treatment 1016990.0 162000.0 0.88 813837.0 -125000.0 -0.7 0.1267 0.1123 3625136 CBKinase1_014336 COc1cccc(OCCSc2nc(N)cc(N)n2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A19 compound treatment 1038009.0 183000.0 1.0 1018431.0 79800.0 0.45 1.0233 0.9353 3625137 CBKinase1_014337 Cc1cccc(NC(=O)C(=O)NCCCO)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A20 compound treatment 903372.0 48000.0 0.26 977108.0 38500.0 0.22 0.3388 0.9956 3625138 CBKinase1_014338 NC(=O)CN(Cc1ccc(F)cc1)S(=O)(=O)c2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A21 compound treatment 872125.0 16800.0 0.09 844577.0 -94000.0 -0.53 -0.31 -0.5764 1228030 CBKinase1_014339 CCOC(=O)C1CCCN(C1)S(=O)(=O)c2cccc3cccnc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A22 compound treatment 870035.0 14700.0 0.08 740302.0 -198000.0 -1.12 -0.7337 -0.6547 3625139 CBKinase1_014340 COc1ccc2N(C(=O)CSc3nnc(C)s3)C(C)(C)CC(C)c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A23 compound treatment 592685.0 -263000.0 -1.43 789624.0 -149000.0 -0.84 -1.6078 -0.9675 3625140 CBKinase1_014341 [O-][N+](=O)c1ccc(NC(=O)CC2Sc3ccc(Cl)cc3NC2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 A24 compound treatment 870054.0 14700.0 0.08 691917.0 -247000.0 -1.39 -0.9265 -0.6652 1871012 CBKinase1_014342 COc1ccc2N(C(=O)CSc3nc4ccccc4[nH]3)C(C)(C)CC(C)c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B01 compound treatment 838170.0 -17200.0 -0.09 968535.0 29900.0 0.17 0.0529 0.2742 3625141 CBKinase1_014343 COC(=O)CCN(C(=O)c1ccc(OC(=O)C)cc1)c2ccccn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B02 compound treatment 266026.0 -589000.0 -3.22 270807.0 -668000.0 -3.76 -4.9366 -0.9969 1475969 CBKinase1_014344 Oc1c(ccc2cccnc12)C(Nc3ccccn3)c4ccc(Br)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B03 compound treatment 992035.0 137000.0 0.75 999531.0 60900.0 0.34 0.7704 0.9379 3625142 CBKinase1_014345 Clc1cccc(NC(=O)CCn2cnc3ccccc3c2=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B04 compound treatment 252762.0 -603000.0 -3.29 246460.0 -692000.0 -3.9 -5.0849 -0.9964 1879467 CBKinase1_014346 Oc1c(ccc2cccnc12)C(Nc3ccccn3)c4ccccc4[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B05 compound treatment 1007714.0 152000.0 0.83 1006199.0 67600.0 0.38 0.8576 0.9373 1480982 CBKinase1_014347 Cc1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4cccc(F)c4)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B06 compound treatment 991293.0 136000.0 0.74 939513.0 899.0 0.01 0.5284 0.7119 3625143 CBKinase1_014348 Cc1c(Cl)cccc1NC(=O)CN(c2ccc(F)cc2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B07 compound treatment 258319.0 -597000.0 -3.26 259633.0 -679000.0 -3.83 -5.0109 -0.9968 3625144 CBKinase1_014349 Cc1cccc(NC(c2ccc(cc2)[N+](=O)[O-])c3ccc4ccc(C)nc4c3O)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B08 compound treatment 985336.0 130000.0 0.71 966206.0 27600.0 0.16 0.6118 0.8421 3625145 CBKinase1_014350 [O-][N+](=O)c1ccccc1OCC(=O)Nc2cccc(c2)c3nc4cc(Cl)cc(Cl)c4o3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B09 compound treatment 882395.0 27000.0 0.15 880804.0 -57800.0 -0.33 -0.126 -0.3522 3625146 CBKinase1_014351 COc1cccc(c1)C(=O)NC(c2ccc(cc2)[N+](=O)[O-])c3c(O)ccc4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B10 compound treatment 1048986.0 194000.0 1.06 907208.0 -31400.0 -0.18 0.6223 0.5806 1297780 CBKinase1_014352 COc1ccc(OC)c(c1)N(CC(=O)N2CCC(C)CC2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B11 compound treatment 923491.0 68100.0 0.37 906174.0 -32400.0 -0.18 0.1338 0.3227 1280892 CBKinase1_014353 COc1ccc(CCNC(=O)c2ccccc2Sc3ccccc3C#N)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B12 compound treatment 992827.0 137000.0 0.75 739723.0 -199000.0 -1.12 -0.262 -0.1942 3625147 CBKinase1_014354 Brc1ccc(cc1)S(=O)(=O)NCCSc2ccccn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B13 mock treatment 901320.0 46000.0 0.25 987637.0 49000.0 0.28 0.3728 0.9988 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B14 mock treatment 992415.0 137000.0 0.75 916093.0 -22500.0 -0.13 0.4394 0.5789 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B15 compound treatment 1090728.0 235000.0 1.29 1037275.0 98700.0 0.56 1.3019 0.9298 3625148 CBKinase1_014355 Cc1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4c(F)c(F)c(F)c(F)c4F)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B16 compound treatment 932602.0 77300.0 0.42 856932.0 -81700.0 -0.46 -0.0273 -0.0438 3625149 CBKinase1_014356 Cc1ccc(NC(=O)c2ccco2)c(NC(=O)COc3ccccc3Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B17 compound treatment 889904.0 34600.0 0.19 906960.0 -31700.0 -0.18 0.0072 0.0278 1163388 CBKinase1_014357 CN(C)C(=O)c1ccc(Nc2nnc(c3ccc(C)c(c3)S(=O)(=O)N)c4ccccc24)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B18 compound treatment 945660.0 90300.0 0.49 1024325.0 85700.0 0.48 0.6902 0.9999 3625150 CBKinase1_014358 CN(CC(=O)Nc1ccc(NC(=O)C)cc1)S(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B19 compound treatment 578696.0 -277000.0 -1.51 621423.0 -317000.0 -1.79 -2.3322 -0.9965 1389302 CBKinase1_014359 CCN(CC)C(=O)c1ccc(Nc2nnc(c3ccc(C)c(c3)S(=O)(=O)N)c4ccccc24)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B20 compound treatment 897435.0 42100.0 0.23 963878.0 25300.0 0.14 0.2632 0.9735 3625151 CBKinase1_014360 NC(=O)C1(CCN(CC(=O)Nc2ccc(Oc3ccccc3)cc2)CC1)N4CCCCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B21 compound treatment 946537.0 91200.0 0.5 965657.0 27000.0 0.15 0.4598 0.8831 1487364 CBKinase1_014361 COc1ccc(OCC(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4o3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B22 compound treatment 909236.0 53900.0 0.29 872396.0 -66200.0 -0.37 -0.0559 -0.1176 3625152 CBKinase1_014362 COC(=O)c1cc(OC)c(OC)cc1NC(=O)COc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B23 compound treatment 621411.0 -234000.0 -1.28 954002.0 15400.0 0.09 -0.8418 -0.6576 1404399 CBKinase1_014363 OC(=O)C(Oc1ccc2c(cc(=O)oc2c1)c3ccccc3)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 B24 compound treatment 773536.0 -81800.0 -0.45 816897.0 -122000.0 -0.69 -0.801 -0.9784 3625153 CBKinase1_014364 COc1ccc(cc1)n2c(SCC(=O)Nc3ccc(C)cc3)nc4sc5CCCCc5c4c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C01 compound treatment 680895.0 -174000.0 -0.95 915651.0 -23000.0 -0.13 -0.765 -0.7959 3625154 CBKinase1_014365 COc1ccc(OC)c(NS(=O)(=O)c2ccc(NC(=O)C3COc4ccccc4O3)cc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C02 compound treatment 782214.0 -73100.0 -0.4 804875.0 -134000.0 -0.75 -0.8154 -0.9558 1127427 CBKinase1_014366 CC(C)(C)NC(=O)Cn1c(nc2ccccc12)c3nonc3N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C03 compound treatment 752918.0 -102000.0 -0.56 811095.0 -128000.0 -0.72 -0.9037 -0.9923 1875161 CBKinase1_014367 O=C(CN1C(=O)c2ccccc2C1=O)Nc3ccc(cc3)S(=O)(=O)N4CCOCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C04 compound treatment 812929.0 -42400.0 -0.23 787972.0 -151000.0 -0.85 -0.7642 -0.8683 3625155 CBKinase1_014368 [O-][N+](=O)c1cccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4)cc3s2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C05 compound treatment 702411.0 -153000.0 -0.83 913103.0 -25500.0 -0.14 -0.6921 -0.8169 3625156 CBKinase1_014369 [O-][N+](=O)c1ccc2[nH]c(SCC(=O)Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F)nc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C06 compound treatment 809216.0 -46100.0 -0.25 673450.0 -265000.0 -1.49 -1.2349 -0.8148 3625157 CBKinase1_014370 Fc1ccc(c(F)c1)n2nnnc2SCC(=O)Nc3ccc4OCCOc4c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C07 compound treatment 764999.0 -90400.0 -0.49 965370.0 26800.0 0.15 -0.2422 -0.4695 3625158 CBKinase1_014371 CC(=O)c1cccc(NC(=O)CN(C2CCCCC2)S(=O)(=O)c3ccc(Br)cc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C08 compound treatment 877225.0 21900.0 0.12 903419.0 -35200.0 -0.2 -0.0558 -0.2411 1548110 CBKinase1_014372 COC(=O)c1ccccc1NC(=S)NC(=O)COc2ccc(C)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C09 compound treatment 619897.0 -235000.0 -1.29 882733.0 -55900.0 -0.31 -1.1317 -0.8551 3625159 CBKinase1_014373 CC(=O)Nc1ccc(cc1)n2c(CCC(=O)O)ccc2c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C10 compound treatment 835799.0 -19600.0 -0.11 853309.0 -85300.0 -0.48 -0.4155 -0.8436 1974364 CBKinase1_014374 CN(C)c1nc(Oc2ccc(OCCOc3ccccc3)nn2)nc(n1)N(C)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C11 mock treatment 903125.0 47800.0 0.26 986789.0 48200.0 0.27 0.3764 0.9998 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C12 mock treatment 755039.0 -100000.0 -0.55 951949.0 13300.0 0.08 -0.3341 -0.6044 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C13 compound treatment 722301.0 -133000.0 -0.73 899265.0 -39300.0 -0.22 -0.6705 -0.8828 3625160 CBKinase1_014375 COc1ccc(CC(=O)Nc2cccc(c2)C(=O)Nc3ccccc3C(=O)O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C14 compound treatment 801595.0 -53800.0 -0.29 837802.0 -101000.0 -0.57 -0.6093 -0.9527 3625161 CBKinase1_014376 COc1ccc(Cl)cc1NC(=O)COc2ccccc2[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C15 mock treatment 926298.0 70900.0 0.39 1033913.0 95300.0 0.54 0.6537 0.9871 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C16 mock treatment 647362.0 -208000.0 -1.14 964717.0 26100.0 0.15 -0.6989 -0.6104 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C17 compound treatment 877635.0 22300.0 0.12 939948.0 1330.0 0.01 0.0913 0.7494 1411409 CBKinase1_014377 Fc1ccc(cc1)C(=O)c2oc3ccccc3c2NC(=O)CSc4ccccn4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C18 compound treatment 918693.0 63300.0 0.35 914106.0 -24500.0 -0.14 0.1468 0.3943 1477211 CBKinase1_014378 CCOC(=O)c1c(C)oc2ccc(OCC(=O)c3ccc(Cl)cc3)cc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C19 compound treatment 798644.0 -56700.0 -0.31 886139.0 -52500.0 -0.3 -0.4281 -0.9997 3625162 CBKinase1_014379 Cc1c(C#N)c2ccccc2n1CC(=O)NCCc3c[nH]c4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C20 compound treatment 630523.0 -225000.0 -1.23 876688.0 -61900.0 -0.35 -1.1148 -0.8735 3625163 CBKinase1_014380 CCOc1ccccc1C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C21 compound treatment 749848.0 -106000.0 -0.58 782616.0 -156000.0 -0.88 -1.029 -0.979 3625164 CBKinase1_014381 Cc1ccc(NC(=O)CSc2nc(c([nH]2)c3ccccc3)c4ccccc4)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C22 compound treatment 749075.0 -106000.0 -0.58 709039.0 -230000.0 -1.29 -1.3253 -0.9345 1168469 CBKinase1_014382 CCc1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccccc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C23 compound treatment 706220.0 -149000.0 -0.81 831951.0 -107000.0 -0.6 -1.0008 -0.9889 3625165 CBKinase1_014383 COc1ccc2nc(Nc3nc(=O)cc(CSc4ccc(Cl)cc4)[nH]3)nc(C)c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 C24 compound treatment 981988.0 127000.0 0.69 676473.0 -262000.0 -1.48 -0.5559 -0.3408 3625166 CBKinase1_014384 CN(C)CCCNc1c([N+](=O)[O-])c(=O)n(C)c2ccccc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D01 compound treatment 774973.0 -80400.0 -0.44 811382.0 -127000.0 -0.72 -0.8174 -0.9722 1346181 CBKinase1_014385 Clc1cc(Cl)c(OCC(=O)Nc2cccnc2)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D02 compound treatment 747928.0 -107000.0 -0.59 833169.0 -105000.0 -0.59 -0.835 -1.0 3625167 CBKinase1_014386 CC(=O)Nc1cc(NC(=O)CCCC(=O)O)ccc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D03 compound treatment 625151.0 -230000.0 -1.26 1835217.0 897000.0 5.05 2.6848 0.5156 3625168 CBKinase1_014387 O=c1[nH]c2ccccc2n1CCCSc3nnc4c5ccccc5[nH]c4n3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D04 compound treatment 562537.0 -293000.0 -1.6 629175.0 -309000.0 -1.74 -2.3637 -0.9991 1728813 CBKinase1_014388 Oc1c(ccc2cccnc12)C(Nc3ccccn3)c4ccc(F)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D05 compound treatment 1035623.0 180000.0 0.98 1154995.0 216000.0 1.22 1.5583 0.9943 1357182 CBKinase1_014389 COc1ccc(OC)c(NC(=O)c2c(NC(=O)c3ccccc3)sc4CC(C)CCc24)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D06 compound treatment 253823.0 -602000.0 -3.28 254784.0 -684000.0 -3.85 -5.0476 -0.9968 1977739 CBKinase1_014390 COc1ccc(cc1)C(=O)NC(c2ccc(cc2)[N+](=O)[O-])c3cc(Cl)c4cccnc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D07 compound treatment 731108.0 -124000.0 -0.68 901625.0 -37000.0 -0.21 -0.6271 -0.8836 3625169 CBKinase1_014391 [O-][N+](=O)c1cc(ccc1NCc2ccco2)C(=O)Nc3cccc(Cl)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D08 compound treatment 838427.0 -16900.0 -0.09 905768.0 -32800.0 -0.19 -0.1962 -0.9485 1248511 CBKinase1_014392 Cc1ccc(N(CC(=O)Nc2cc(Cl)ccc2C)S(=O)(=O)C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D09 compound treatment 927915.0 72600.0 0.4 937537.0 -1080.0 -0.01 0.2758 0.6962 3625170 CBKinase1_014393 Cc1ccc(cc1)S(=O)(=O)N[C@H](C(=O)Oc2ccc3c(cc(=O)oc3c2)C(F)(F)F)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D10 compound treatment 747918.0 -107000.0 -0.59 970743.0 32100.0 0.18 -0.2867 -0.467 1703347 CBKinase1_014394 Cc1ccc(Cl)cc1N(CC(=O)Nc2ccc(cc2)C(=O)N)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D11 mock treatment 691717.0 -164000.0 -0.89 850597.0 -88000.0 -0.5 -0.9825 -0.9615 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D12 mock treatment 839046.0 -16300.0 -0.09 878246.0 -60400.0 -0.34 -0.3035 -0.8631 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D13 compound treatment 822181.0 -33200.0 -0.18 993323.0 54700.0 0.31 0.09 0.2516 3625172 CBKinase1_014395 O=C(COc1ccccc1)Nc2ccc3oc(nc3c2)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D14 compound treatment 738015.0 -117000.0 -0.64 958225.0 19600.0 0.11 -0.3748 -0.5766 3625173 CBKinase1_014396 COc1cccc(NC(=O)CSc2nc3ccccc3n2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D15 mock treatment 818515.0 -36800.0 -0.2 951117.0 12500.0 0.07 -0.0924 -0.4335 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D16 mock treatment 792384.0 -63000.0 -0.34 952239.0 13600.0 0.08 -0.1888 -0.5359 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D17 compound treatment 895022.0 39700.0 0.22 1040165.0 102000.0 0.57 0.5579 0.9116 3625174 CBKinase1_014397 COC(=O)c1ccc(NC(=O)CCC(=O)c2ccc(Br)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D18 compound treatment 891378.0 36000.0 0.2 1049970.0 111000.0 0.63 0.5829 0.8862 3625175 CBKinase1_014398 CN(CC(=O)Nc1ccc(cc1)C(F)(F)F)S(=O)(=O)c2ccc(C)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D19 compound treatment 743932.0 -111000.0 -0.61 806055.0 -133000.0 -0.75 -0.9585 -0.9948 1256149 CBKinase1_014399 COc1ccc(OCC(=O)Nc2cc(ccc2C)c3nc4ccccc4s3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D20 compound treatment 713037.0 -142000.0 -0.78 837304.0 -101000.0 -0.57 -0.9532 -0.9885 3625176 CBKinase1_014400 COc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccccc2)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D21 compound treatment 665449.0 -190000.0 -1.04 810436.0 -128000.0 -0.72 -1.244 -0.9844 1658278 CBKinase1_014401 CCCc1c(C)nc2ccc(Br)cc2c1SCCC(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D22 compound treatment 649512.0 -206000.0 -1.12 802479.0 -136000.0 -0.77 -1.3372 -0.9827 3625177 CBKinase1_014402 O=C(CSc1ncnc2sc(cc12)c3ccccc3)NC4CCCCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D23 compound treatment 668190.0 -187000.0 -1.02 849806.0 -88800.0 -0.5 -1.0765 -0.9461 1225587 CBKinase1_014403 O=C(CSc1nc2ccccc2[nH]1)n3c4CCCCc4c5ccccc35 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 D24 compound treatment 792051.0 -63300.0 -0.35 790858.0 -148000.0 -0.83 -0.8333 -0.9241 1545093 CBKinase1_014404 CCC(Sc1nc2ccccc2n1CC)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E01 mock treatment 812063.0 -43300.0 -0.24 893576.0 -45000.0 -0.25 -0.3466 -0.9994 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E02 mock treatment 792465.0 -62900.0 -0.34 896433.0 -42200.0 -0.24 -0.4109 -0.9839 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E03 compound treatment 797324.0 -58000.0 -0.32 818179.0 -120000.0 -0.68 -0.704 -0.9398 3625178 CBKinase1_014405 CC(C)Cc1nnc(SCC(=O)Nc2ccc3ccccc3c2)[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E04 compound treatment 752491.0 -103000.0 -0.56 861335.0 -77300.0 -0.44 -0.7051 -0.9921 3625179 CBKinase1_014406 Cc1ccc2nc(oc2c1)c3ccc(C)c(NC(=O)COc4ccc(cc4)[N+](=O)[O-])c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E05 compound treatment 867063.0 11700.0 0.06 896058.0 -42600.0 -0.24 -0.1244 -0.5011 1621691 CBKinase1_014407 CCCc1cc(=O)oc2cc(OCc3cc(oc3C)C(=O)O)ccc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E06 compound treatment 788859.0 -66500.0 -0.36 810054.0 -129000.0 -0.72 -0.7691 -0.9489 3625180 CBKinase1_014408 CC(=O)c1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4Cl)cc3s2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E07 compound treatment 784817.0 -70500.0 -0.39 807054.0 -132000.0 -0.74 -0.7966 -0.9534 3625181 CBKinase1_014409 COC(=O)c1cccc(NC(=O)COc2ccc(cc2)[N+](=O)[O-])c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E08 compound treatment 800789.0 -54600.0 -0.3 976740.0 38100.0 0.21 -0.0587 -0.1598 3625182 CBKinase1_014410 CCOC(=O)c1c(NC(=O)C2CC(=CCC2C(=O)O)Cl)sc3CCC(C)Cc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E09 mock treatment 880908.0 25600.0 0.14 863134.0 -75500.0 -0.43 -0.2022 -0.4515 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E10 mock treatment 785726.0 -69600.0 -0.38 848991.0 -89600.0 -0.51 -0.626 -0.9902 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E11 compound treatment 842595.0 -12800.0 -0.07 976582.0 38000.0 0.21 0.1021 0.4536 1510683 CBKinase1_014411 CC(=O)Nc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E12 compound treatment 870855.0 15500.0 0.08 906149.0 -32500.0 -0.18 -0.0695 -0.3449 3625183 CBKinase1_014412 Fc1ccccc1NC(=O)CN(C2CCCCC2)S(=O)(=O)c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E13 compound treatment 894070.0 38700.0 0.21 984016.0 45400.0 0.26 0.3304 0.9955 1233165 CBKinase1_014413 Cc1oc(cc1COc2ccc3c(C)c(Cc4ccccc4)c(=O)oc3c2C)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E14 compound treatment 849655.0 -5700.0 -0.03 937827.0 -787.0 0.0 -0.0251 -0.7999 3625184 CBKinase1_014414 CCOC(=O)c1c(C)oc2ccc(OCc3cccc(c3)[N+](=O)[O-])cc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E15 compound treatment 873245.0 17900.0 0.1 850481.0 -88100.0 -0.5 -0.2822 -0.5574 1373814 CBKinase1_014415 CCc1cc(=O)oc2cc(OCc3cc(oc3C)C(=O)OC)ccc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E16 compound treatment 1008995.0 154000.0 0.84 1018882.0 80300.0 0.45 0.913 0.958 3625185 CBKinase1_014416 FC(F)(F)c1ccccc1NC(=O)CSc2nc3CCCCCc3cc2C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E17 mock treatment 765638.0 -89700.0 -0.49 863440.0 -75200.0 -0.42 -0.6459 -0.9974 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E18 mock treatment 868504.0 13200.0 0.07 794448.0 -144000.0 -0.81 -0.5238 -0.6421 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E19 compound treatment 767996.0 -87400.0 -0.48 746745.0 -192000.0 -1.08 -1.1019 -0.9323 1254237 CBKinase1_014417 CCOC(=O)c1c(C)oc2ccc(OCc3cc(oc3C)C(=O)OC)cc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E20 compound treatment 809466.0 -45900.0 -0.25 875252.0 -63400.0 -0.36 -0.4297 -0.985 3625186 CBKinase1_014418 [O-][N+](=O)c1ccccc1c2ccc(o2)C(=O)NCc3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E21 compound treatment 679310.0 -176000.0 -0.96 769367.0 -169000.0 -0.95 -1.3541 -1.0 3625187 CBKinase1_014419 Cc1ccc(cc1)c2noc(CSc3nnnn3c4ccccc4)n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E22 compound treatment 761406.0 -93900.0 -0.51 860886.0 -77700.0 -0.44 -0.6725 -0.9969 1729077 CBKinase1_014420 Clc1cccc(c1)c2nc3cc(NC(=O)COc4ccccc4)ccc3o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E23 compound treatment 727744.0 -128000.0 -0.7 742564.0 -196000.0 -1.11 -1.274 -0.9753 3625188 CBKinase1_014421 COC(=O)c1ccc(cc1)n2nnnc2SCC(=O)Nc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 E24 compound treatment 712457.0 -143000.0 -0.78 781234.0 -157000.0 -0.89 -1.1789 -0.9979 1687685 CBKinase1_014422 Cc1cccc(c1)N2C(=O)NC(=O)C(CCc3ccncc3)(CCc4ccncc4)C2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F01 mock treatment 760924.0 -94400.0 -0.52 766441.0 -172000.0 -0.97 -1.0507 -0.9562 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F02 mock treatment 697849.0 -158000.0 -0.86 809096.0 -130000.0 -0.73 -1.1242 -0.9967 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F03 compound treatment 812978.0 -42400.0 -0.23 846223.0 -92400.0 -0.52 -0.5318 -0.9333 1259509 CBKinase1_014423 COc1cccc(c1)C2N(CCN3CCOCC3)C(=O)C(=C2C(=O)c4cccs4)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F04 compound treatment 683099.0 -172000.0 -0.94 823996.0 -115000.0 -0.65 -1.1218 -0.9832 3625189 CBKinase1_014424 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2ccc(C)cc2[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F05 compound treatment 720343.0 -135000.0 -0.74 837818.0 -101000.0 -0.57 -0.9229 -0.9917 3625190 CBKinase1_014425 [O-][N+](=O)c1ccc2[nH]c(CSc3nc4ccccc4[nH]3)nc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F06 compound treatment 860719.0 5370.0 0.03 857088.0 -81500.0 -0.46 -0.3042 -0.6607 3625191 CBKinase1_014426 Cc1ccc(NC(=O)CCC(=O)c2ccc(Oc3ccccc3)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F07 compound treatment 269586.0 -586000.0 -3.2 267672.0 -671000.0 -3.78 -4.9354 -0.9965 1459392 CBKinase1_014427 Cc1cccc(NC(c2ccc(Br)cc2)c3ccc4cccnc4c3O)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F08 compound treatment 685511.0 -170000.0 -0.93 834782.0 -104000.0 -0.59 -1.0695 -0.9754 1231321 CBKinase1_014428 CCOC(=O)c1ccccc1NC(=O)CC2Nc3ccccc3NC2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F09 mock treatment 876729.0 21400.0 0.12 908494.0 -30100.0 -0.17 -0.0375 -0.1821 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F10 mock treatment 747847.0 -108000.0 -0.59 832379.0 -106000.0 -0.6 -0.8384 -0.9999 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F11 compound treatment 759556.0 -95800.0 -0.52 931499.0 -7110.0 -0.04 -0.3982 -0.7591 3625192 CBKinase1_014429 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccccc2C)C3CCCCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F12 compound treatment 820227.0 -35100.0 -0.19 835554.0 -103000.0 -0.58 -0.5463 -0.8931 1450811 CBKinase1_014430 COc1ccccc1CC(=O)Nc2ccccc2C(=O)NC(C)(C)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F13 compound treatment 796378.0 -59000.0 -0.32 842166.0 -96400.0 -0.54 -0.6121 -0.9687 3625193 CBKinase1_014431 Cc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)Nc4ccc(cc4)[N+](=O)[O-])sc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F14 compound treatment 669857.0 -185000.0 -1.01 847952.0 -90700.0 -0.51 -1.0774 -0.9498 3625194 CBKinase1_014432 O=C(CCCN1C(=O)c2cccc3cccc(C1=O)c23)N4CCN(CC4)c5ncccn5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F15 compound treatment 625609.0 -230000.0 -1.25 853291.0 -85300.0 -0.48 -1.227 -0.9134 3625195 CBKinase1_014433 COc1cc(ccc1NC(=S)NC(=O)COc2ccc(C)cc2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F16 compound treatment 766871.0 -88500.0 -0.48 709552.0 -229000.0 -1.29 -1.2545 -0.9101 3625196 CBKinase1_014434 CC(C)c1cccc(C(C)C)c1NC(=O)Cn2cnc3sc4CC(C)CCc4c3c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F17 mock treatment 608848.0 -247000.0 -1.35 829349.0 -109000.0 -0.62 -1.3871 -0.9372 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F18 mock treatment 734771.0 -121000.0 -0.66 863797.0 -74800.0 -0.42 -0.7637 -0.9768 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F19 compound treatment 806866.0 -48500.0 -0.26 673425.0 -265000.0 -1.49 -1.2441 -0.8196 1176853 CBKinase1_014435 Cc1ccc(OCC(=O)NC(=S)Nc2cccc(NC(=O)c3ccccc3Cl)c2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F20 compound treatment 642093.0 -213000.0 -1.16 797763.0 -141000.0 -0.79 -1.3846 -0.9826 3625197 CBKinase1_014436 Cc1cc(Br)c(cc1C)S(=O)(=O)NCc2ccccn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F21 compound treatment 731641.0 -124000.0 -0.68 694353.0 -244000.0 -1.38 -1.4511 -0.9463 1721236 CBKinase1_014437 Cc1ccc(cc1NC(=O)COc2ccc(Cl)cc2)c3nc4ccccc4s3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F22 compound treatment 608242.0 -247000.0 -1.35 716992.0 -222000.0 -1.25 -1.8372 -0.9993 1323078 CBKinase1_014438 COc1ccc(NC(=O)c2ccc(Cn3cc(Br)cn3)cc2)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F23 compound treatment 573665.0 -282000.0 -1.54 660492.0 -278000.0 -1.57 -2.1959 -1.0 1481987 CBKinase1_014439 COc1cc(NC(=O)C(C)Oc2ccc(Cl)cc2Cl)c(OC)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 F24 compound treatment 636656.0 -219000.0 -1.19 808954.0 -130000.0 -0.73 -1.361 -0.9722 3625198 CBKinase1_014440 Cc1ccc(cc1NC(=O)COc2ccc(cc2)C(C)(C)C)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G01 compound treatment 957961.0 103000.0 0.56 968346.0 29700.0 0.17 0.5146 0.8801 3625199 CBKinase1_014441 CC(=O)Nc1cccc(NC(=O)CNc2ccc(cc2[N+](=O)[O-])C(F)(F)F)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G02 compound treatment 945060.0 89700.0 0.49 940185.0 1570.0 0.01 0.3526 0.7198 1437336 CBKinase1_014442 CCCn1c2ccccc2c3nnc(SCC(=O)N4c5ccccc5Sc6ccccc46)nc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G03 mock treatment 990461.0 135000.0 0.74 938869.0 255.0 0.0 0.5226 0.7085 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G04 mock treatment 896322.0 41000.0 0.22 981073.0 42500.0 0.24 0.3274 0.9994 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G05 compound treatment 955858.0 101000.0 0.55 991333.0 52700.0 0.3 0.5981 0.9585 1250158 CBKinase1_014443 OC1(CC(=O)c2ccc(OCC(=O)N3CCOCC3)cc2)C(=O)Nc4ccccc41 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G06 compound treatment 994311.0 139000.0 0.76 1018895.0 80300.0 0.45 0.8564 0.9695 1228895 CBKinase1_014444 Fc1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4Cl)cc3s2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G07 compound treatment 989374.0 134000.0 0.73 990715.0 52100.0 0.29 0.725 0.9196 3625200 CBKinase1_014445 CC(C)(C)c1ccc(OCC(=O)Nc2ccc(cc2)C(=O)Nc3ccccc3C(=O)O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G08 compound treatment 1001691.0 146000.0 0.8 1005325.0 66700.0 0.38 0.8308 0.9409 3625201 CBKinase1_014446 Cc1nc(NS(=O)(=O)c2ccc(C)cc2)sc1NC(=O)Nc3ccc(Cl)cc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G09 compound treatment 975459.0 120000.0 0.66 1022692.0 84100.0 0.47 0.7988 0.9873 3625202 CBKinase1_014447 Nc1nc(CSc2ccccn2)nc(Nc3ccccc3)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G10 compound treatment 963944.0 109000.0 0.59 1007635.0 69000.0 0.39 0.6943 0.9791 1862850 CBKinase1_014448 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccc(F)cc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G11 compound treatment 1002997.0 148000.0 0.81 1043328.0 105000.0 0.59 0.9873 0.9883 3625203 CBKinase1_014449 COc1cc(NC(=O)c2ccccc2)c(OC)cc1NC(=O)C3c4ccccc4Oc5ccccc35 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G12 compound treatment 1009436.0 154000.0 0.84 993624.0 55000.0 0.31 0.8141 0.908 1504700 CBKinase1_014450 Cc1sc2ncn(CC(=O)NCc3ccco3)c(=O)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G13 compound treatment 969305.0 114000.0 0.62 1916206.0 978000.0 5.51 4.3361 0.782 1542589 CBKinase1_014451 CCN1CCN(Cc2c(C)nc3ccc(Cl)cc3c2O)CC1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G14 compound treatment 981949.0 127000.0 0.69 988275.0 49700.0 0.28 0.6866 0.9208 1211282 CBKinase1_014452 COC(=O)c1c(C)oc2cc(Br)c(OCC(=O)c3ccc(F)cc3)cc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G15 compound treatment 948885.0 93500.0 0.51 1004336.0 65700.0 0.37 0.623 0.9876 3625204 CBKinase1_014453 Cc1ccc(cc1)c2noc(CSc3nc(C)cc(C)n3)n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G16 compound treatment 1475390.0 620000.0 3.39 1348511.0 410000.0 2.31 4.0273 0.9827 1273596 CBKinase1_014454 COc1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccc(C)c(C)c4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G17 compound treatment 1050752.0 195000.0 1.07 1116725.0 178000.0 1.0 1.4642 0.9995 1136162 CBKinase1_014455 CCc1cc2c(=O)c(c3nc(C)cs3)c(CCCC(=O)O)oc2cc1O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G18 compound treatment 944281.0 88900.0 0.49 993360.0 54700.0 0.31 0.5615 0.9761 1539046 CBKinase1_014456 Cc1sc2ncnc(Nc3cccc(c3)C(=O)O)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G19 mock treatment 949522.0 94200.0 0.51 935804.0 -2810.0 -0.02 0.3523 0.685 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G20 mock treatment 931708.0 76400.0 0.42 891021.0 -47600.0 -0.27 0.1051 0.212 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G21 compound treatment 836304.0 -19000.0 -0.1 949670.0 11100.0 0.06 -0.0295 -0.2431 3625205 CBKinase1_014457 [O-][N+](=O)c1ccc2[nH]c(CSc3nc4ccccc4s3)nc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G22 compound treatment 899491.0 44100.0 0.24 921621.0 -17000.0 -0.1 0.1027 0.3959 1206697 CBKinase1_014458 CC1CCc2sc3ncnc(NCCN4CCOCC4)c3c2C1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G23 compound treatment 877170.0 21800.0 0.12 848223.0 -90400.0 -0.51 -0.276 -0.5276 1402130 CBKinase1_014459 Cc1cc(C)c(OCC(=O)Nc2cccnc2)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 G24 compound treatment 912624.0 57300.0 0.31 933888.0 -4730.0 -0.03 0.2023 0.6445 3625206 CBKinase1_014460 O=C(Cc1cccnc1)Nc2c3CCCc3nc4CCCCc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H01 compound treatment 927847.0 72500.0 0.4 1019820.0 81200.0 0.46 0.6035 0.9974 1656247 CBKinase1_014461 COc1cccc(C2N(CCN(C)C)C(=O)C(=C2C(=O)c3ccco3)O)c1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H02 compound treatment 891605.0 36300.0 0.2 906859.0 -31800.0 -0.18 0.0134 0.0502 1430284 CBKinase1_014462 COC(=O)C1=C(C)NC(=S)NC1c2cccc(OC)c2OCc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H03 mock treatment 908722.0 53400.0 0.29 973820.0 35200.0 0.2 0.3463 0.9825 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H04 mock treatment 932202.0 76900.0 0.42 991137.0 52500.0 0.3 0.506 0.9854 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H05 compound treatment 946556.0 91200.0 0.5 997268.0 58700.0 0.33 0.5859 0.9802 3625207 CBKinase1_014463 COc1cc(Br)c(CCNC(=O)c2ccco2)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H06 compound treatment 971072.0 116000.0 0.63 990862.0 52200.0 0.29 0.655 0.9396 1740911 CBKinase1_014464 Clc1ccc(c(Cl)c1Cl)S(=O)(=O)NCc2ccccn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H07 compound treatment 973280.0 118000.0 0.64 983220.0 44600.0 0.25 0.633 0.9159 1335893 CBKinase1_014465 Clc1cc(Cl)c(cc1Cl)S(=O)(=O)NCc2ccccn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H08 compound treatment 891927.0 36600.0 0.2 1024586.0 86000.0 0.48 0.4838 0.9232 1442684 CBKinase1_014466 COc1cccc(c1)N(CC(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H09 compound treatment 993056.0 138000.0 0.75 1034858.0 96200.0 0.54 0.9152 0.9872 3625208 CBKinase1_014467 Cc1ccc(cc1[N+](=O)[O-])C(=O)CC2(O)C(=O)Nc3ccccc32 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H10 compound treatment 974328.0 119000.0 0.65 1062659.0 124000.0 0.7 0.9537 0.9993 1605646 CBKinase1_014468 CC(c1ccccc1)n2c(CCCO)nc3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H11 compound treatment 1022630.0 167000.0 0.91 1039286.0 101000.0 0.57 1.047 0.9738 3625209 CBKinase1_014469 Cc1ccnc(NS(=O)(=O)c2cc(ccc2C)[N+](=O)[O-])c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H12 compound treatment 985671.0 130000.0 0.71 1014698.0 76100.0 0.43 0.8063 0.9706 3625210 CBKinase1_014470 COc1cc(cc(OC)c1OC)C(=O)NC(=S)Nc2cccc(c3nc4ncccc4o3)c2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H13 compound treatment 942891.0 87500.0 0.48 941047.0 2430.0 0.01 0.3476 0.7271 1742447 CBKinase1_014471 CCCn1c2ccccc2c3nnc(SCCN4CCCCC4)nc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H14 compound treatment 950984.0 95600.0 0.52 1059908.0 121000.0 0.68 0.8526 0.9911 3625211 CBKinase1_014472 Fc1cccc(NC(=O)CNS(=O)(=O)c2ccccc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H15 compound treatment 930207.0 74900.0 0.41 997366.0 58800.0 0.33 0.5231 0.9946 1786341 CBKinase1_014473 COc1ccccc1NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4OC)cc3s2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H16 compound treatment 995417.0 140000.0 0.76 1054137.0 116000.0 0.65 1.0011 0.9968 3625212 CBKinase1_014474 Fc1ccc(cc1)C(=O)CSc2nnc(c3ccco3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H17 compound treatment 953371.0 98000.0 0.54 1027620.0 89000.0 0.5 0.7331 0.9995 3625213 CBKinase1_014475 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4cccc(Br)c4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H18 compound treatment 987682.0 132000.0 0.72 1038171.0 99600.0 0.56 0.9076 0.9922 3625214 CBKinase1_014476 CCOC(=O)CSc1ncnc2scc(c3ccc(Cl)cc3)c12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H19 mock treatment 989325.0 134000.0 0.73 962607.0 24000.0 0.14 0.6128 0.8239 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H20 mock treatment 941168.0 85800.0 0.47 979092.0 40500.0 0.23 0.4926 0.9453 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H21 compound treatment 932912.0 77600.0 0.42 991144.0 52500.0 0.3 0.5088 0.9847 1294446 CBKinase1_014477 Cc1nnc(NCc2ccco2)[nH]c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H22 compound treatment 1067452.0 212000.0 1.16 996333.0 57700.0 0.33 1.0488 0.872 3625215 CBKinase1_014478 Cc1cccc(NC(=O)CSc2nnc(o2)c3ccc(Br)cc3)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H23 compound treatment 814595.0 -40800.0 -0.22 879555.0 -59100.0 -0.33 -0.3927 -0.9808 1643016 CBKinase1_014479 CCc1ccc(cc1)C(Nc2ccccn2)c3ccc4ccc(C)nc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 H24 compound treatment 905755.0 50400.0 0.28 952291.0 13700.0 0.08 0.2491 0.8716 3625216 CBKinase1_014480 Cn1c(Cc2cccc3ccccc23)nnc1SCc4ccccc4C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I01 compound treatment 1018166.0 163000.0 0.89 1000789.0 62200.0 0.35 0.8763 0.9172 3625217 CBKinase1_014481 Cc1ccc(C(=O)CSc2nnc(c3cccc(F)c3)n2c4ccccc4)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I02 compound treatment 892868.0 37500.0 0.2 1034880.0 96300.0 0.54 0.5285 0.9113 1719089 CBKinase1_014482 COc1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4cccc(Br)c4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I03 compound treatment 808835.0 -46500.0 -0.25 953758.0 15100.0 0.09 -0.1192 -0.445 3625218 CBKinase1_014483 COc1ccc(NC(=O)CN2CCN(CC2)C(=O)c3ccco3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I04 compound treatment 897867.0 42500.0 0.23 998902.0 60300.0 0.34 0.4044 0.9827 1384350 CBKinase1_014484 CCCn1c2ccccc2c3nnc(SCC(=O)Nc4cccc5ccccc45)nc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I05 mock treatment 870419.0 15100.0 0.08 1010654.0 72000.0 0.41 0.3453 0.8334 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I06 mock treatment 878472.0 23100.0 0.13 992713.0 54100.0 0.3 0.3049 0.9238 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I07 compound treatment 895811.0 40500.0 0.22 1026655.0 88000.0 0.5 0.5071 0.9335 3625219 CBKinase1_014485 COC(=O)c1cc(NC(=O)COc2ccccc2OC)cc(c1)C(=O)OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I08 compound treatment 866781.0 11400.0 0.06 953180.0 14600.0 0.08 0.1022 0.9908 3625220 CBKinase1_014486 [O-][N+](=O)c1ccccc1OCC(=O)Nc2ccc3oc(nc3c2)c4ccc(F)cc4Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I09 compound treatment 897317.0 42000.0 0.23 1024629.0 86000.0 0.48 0.5048 0.9414 3625221 CBKinase1_014487 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2)c3ccccc3Oc4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I10 compound treatment 947586.0 92200.0 0.5 1071537.0 133000.0 0.75 0.8858 0.9813 1336343 CBKinase1_014488 CCOC(=O)c1c(NC(=O)COc2ccc(Cl)cc2C)sc3CCCc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I11 compound treatment 905904.0 50600.0 0.28 1100327.0 162000.0 0.91 0.8397 0.8817 1258026 CBKinase1_014489 Cc1cc(C)n(CC(O)CN2C(=O)NC(C)(C)C2=O)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I12 compound treatment 915933.0 60600.0 0.33 1117735.0 179000.0 1.01 0.9478 0.8921 1862848 CBKinase1_014490 COc1ccc(cc1Cl)c2nc3cc(NC(=O)COc4ccc(cc4)[N+](=O)[O-])ccc3o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I13 compound treatment 853595.0 -1760.0 -0.01 1058278.0 120000.0 0.67 0.4701 0.697 3625222 CBKinase1_014491 CC1(C)NC(=O)N(CC(O)CNC2(CC3CC4CC(C3)C2)C4)C1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I14 compound treatment 913438.0 58100.0 0.32 1028686.0 90100.0 0.51 0.5832 0.9743 1130584 CBKinase1_014492 Cc1ccc(NC(=O)CSc2nc3sc4CCCCc4c3c(=O)n2c5ccccc5)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I15 compound treatment 834375.0 -21000.0 -0.11 994974.0 56400.0 0.32 0.1436 0.4254 3625223 CBKinase1_014493 Clc1cccc(NC(=O)CSc2nc3ccccc3[nH]2)c1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I16 compound treatment 871314.0 16000.0 0.09 1072311.0 134000.0 0.75 0.5945 0.7837 1578426 CBKinase1_014494 Cc1sc2nc3scc(CC(=O)NCCO)n3c(=O)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I17 compound treatment 936566.0 81200.0 0.44 1017568.0 79000.0 0.45 0.6282 1.0 3625224 CBKinase1_014495 Nc1cc(=O)[nH]c(SCC(=O)Nc2ccc(F)cc2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I18 compound treatment 909246.0 53900.0 0.29 1002320.0 63700.0 0.36 0.462 0.9951 3625225 CBKinase1_014496 Cc1c(cccc1[N+](=O)[O-])C(=O)NC(=S)Nc2ncccc2O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I19 compound treatment 864305.0 8950.0 0.05 974570.0 36000.0 0.2 0.1779 0.8532 3625226 CBKinase1_014497 Brc1ccc(NC(=O)CSc2nc(cc(=O)[nH]2)c3ccccc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I20 compound treatment 811851.0 -43500.0 -0.24 986829.0 48200.0 0.27 0.0242 0.0671 3625227 CBKinase1_014498 COC(=O)CNC(=O)c1ccc(cc1)S(=O)(=O)N2CCOCC2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I21 mock treatment 879531.0 24200.0 0.13 983664.0 45100.0 0.25 0.2729 0.9536 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I22 mock treatment 810727.0 -44600.0 -0.24 942753.0 4140.0 0.02 -0.1558 -0.6365 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I23 compound treatment 789598.0 -65800.0 -0.36 989710.0 51100.0 0.29 -0.0502 -0.1091 1412997 CBKinase1_014499 CCc1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccccc4F)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 I24 compound treatment 888341.0 33000.0 0.18 922265.0 -16300.0 -0.09 0.0622 0.3074 1788386 CBKinase1_014500 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2nccs2)C3COc4ccccc4O3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J01 compound treatment 846086.0 -9270.0 -0.05 749430.0 -189000.0 -1.07 -0.7898 -0.7398 1862852 CBKinase1_014501 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccccc4Br)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J02 compound treatment 821280.0 -34100.0 -0.19 890937.0 -47700.0 -0.27 -0.3216 -0.9839 1517675 CBKinase1_014502 COc1ccc(cc1OC)C(Nc2ccccn2)c3ccc4cccnc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J03 compound treatment 856034.0 682.0 0.0 927138.0 -11500.0 -0.06 -0.0431 -0.6653 1349641 CBKinase1_014503 Cc1ccc(Cl)cc1NC(=O)C2CC=CCC2C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J04 compound treatment 837759.0 -17600.0 -0.1 965529.0 26900.0 0.15 0.0394 0.2192 1138447 CBKinase1_014504 OC(=O)CCCC(=O)Nc1ccc(N2CCOCC2)c(c1)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J05 mock treatment 965500.0 110000.0 0.6 1015991.0 77400.0 0.44 0.7336 0.9876 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J06 mock treatment 945881.0 90500.0 0.49 1013478.0 74900.0 0.42 0.6479 0.9969 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J07 compound treatment 918187.0 62800.0 0.34 1006277.0 67700.0 0.38 0.5122 0.9986 1368934 CBKinase1_014505 Cc1cccc(C)c1N(CC(=O)Nc2ccc(Br)c(C)c2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J08 compound treatment 285180.0 -570000.0 -3.11 291686.0 -647000.0 -3.65 -4.7795 -0.9969 1629292 CBKinase1_014506 COc1ccc(cc1)C(=O)NC(c2ccc(OC)c(OC)c2)c3cc(Cl)c4cccnc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J09 compound treatment 2468598.0 1610000.0 8.81 2463981.0 1530000.0 8.6 12.3073 0.9999 1637150 CBKinase1_014507 Cc1ccc(cc1)S(=O)(=O)NCCC(=O)Oc2cc3oc(=O)c4CCCCc4c3cc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J10 compound treatment 932860.0 77500.0 0.42 1092179.0 154000.0 0.87 0.9113 0.9458 1481151 CBKinase1_014508 Cc1ccc2nc(oc2c1)c3ccc(C)c(NC(=O)COc4cc(C)cc(C)c4)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J11 compound treatment 940214.0 84900.0 0.46 1122032.0 183000.0 1.03 1.0586 0.9345 1862846 CBKinase1_014509 Cc1ccc(cc1C)c2nc3cc(NC(=O)COc4ccc(cc4)[N+](=O)[O-])ccc3o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J12 compound treatment 911479.0 56100.0 0.31 1092193.0 154000.0 0.87 0.8288 0.9025 3625228 CBKinase1_014510 COc1ccc(C)cc1N(CC(=O)Nc2ccccc2C(=O)O)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J13 compound treatment 1015172.0 160000.0 0.87 1004363.0 65700.0 0.37 0.879 0.9273 1597085 CBKinase1_014511 CCCn1c2ccccc2c3nnc(SCC(=O)O)nc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J14 compound treatment 947733.0 92400.0 0.5 1099062.0 160000.0 0.9 0.9961 0.962 3625229 CBKinase1_014512 Cc1ccc(Cl)cc1NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J15 compound treatment 915872.0 60500.0 0.33 1077733.0 139000.0 0.78 0.7881 0.9262 3625230 CBKinase1_014513 COc1ccc(cc1)C(=O)CCC(=O)Nc2ccc(Br)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J16 compound treatment 925723.0 70400.0 0.38 1110079.0 171000.0 0.97 0.955 0.9183 1390042 CBKinase1_014514 CC(C)c1ccc(C)cc1OCc2ccc(o2)C(=O)Nc3sc4CCCCc4c3C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J17 compound treatment 977083.0 122000.0 0.66 1019994.0 81400.0 0.46 0.7943 0.9836 1594854 CBKinase1_014515 Cc1ccc(NC(=O)COc2ccc(Cl)cc2)cc1NC(=O)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J18 compound treatment 914205.0 58900.0 0.32 1084943.0 146000.0 0.82 0.8104 0.9156 3625231 CBKinase1_014516 OCCN(C1=NS(=O)(=O)c2ccccc12)c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J19 compound treatment 917566.0 62200.0 0.34 912504.0 -26100.0 -0.15 0.1361 0.3677 3625232 CBKinase1_014517 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccccc4Cl)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J20 compound treatment 904881.0 49500.0 0.27 1043332.0 105000.0 0.59 0.6086 0.9374 1667628 CBKinase1_014518 NC(=O)c1c(NC(=O)c2ccc(COc3cc(Cl)ccc3Cl)o2)sc4CCCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J21 mock treatment 838495.0 -16900.0 -0.09 990896.0 52300.0 0.29 0.1433 0.4642 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J22 mock treatment 883623.0 28300.0 0.15 967384.0 28800.0 0.16 0.2238 0.9997 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J23 compound treatment 496524.0 -359000.0 -1.96 557954.0 -381000.0 -2.15 -2.9024 -0.999 3625233 CBKinase1_014519 Cc1ccc(cc1)C(Nc2ccccn2)c3ccc4cccnc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 J24 compound treatment 864490.0 9140.0 0.05 979293.0 40700.0 0.23 0.1974 0.8413 3625234 CBKinase1_014520 Oc1ccccc1CN(C2=NS(=O)(=O)c3ccccc23)c4ccc(Cl)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K01 compound treatment 710154.0 -145000.0 -0.79 905493.0 -33100.0 -0.19 -0.6925 -0.8504 3022173 CBKinase1_014521 OC(=O)CCC(=O)N1N=C(CC1c2ccccc2F)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K02 compound treatment 811013.0 -44300.0 -0.24 909801.0 -28800.0 -0.16 -0.286 -0.9811 3625235 CBKinase1_014522 COc1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4ccc(C)cc4C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K03 compound treatment 800198.0 -55200.0 -0.3 910262.0 -28400.0 -0.16 -0.3259 -0.9561 3625236 CBKinase1_014523 Cc1oc(cc1COc2cc(C)cc3oc(=O)c4CCCCc4c23)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K04 compound treatment 761678.0 -93700.0 -0.51 868513.0 -70100.0 -0.4 -0.641 -0.9919 1513405 CBKinase1_014524 COc1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4cccc(I)c4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K05 compound treatment 811966.0 -43400.0 -0.24 901254.0 -37400.0 -0.21 -0.3164 -0.9983 3625237 CBKinase1_014525 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc(NC(=O)c3ccccc3)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K06 compound treatment 867553.0 12200.0 0.07 937702.0 -912.0 -0.01 0.0435 0.6506 1973544 CBKinase1_014526 CCC(Sc1nncn1C)C(=O)Nc2ccc(cc2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K07 mock treatment 864014.0 8660.0 0.05 882868.0 -55700.0 -0.31 -0.1887 -0.594 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K08 mock treatment 835770.0 -19600.0 -0.11 953689.0 15100.0 0.08 -0.0155 -0.1136 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K09 compound treatment 801161.0 -54200.0 -0.3 921964.0 -16600.0 -0.09 -0.2756 -0.8878 3625238 CBKinase1_014527 Cc1cc(Cl)ccc1NC(=O)CN(c2ccc(Cl)c(Cl)c2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K10 compound treatment 783516.0 -71800.0 -0.39 800432.0 -138000.0 -0.78 -0.828 -0.9496 1444742 CBKinase1_014528 COc1c(Cl)c(Cl)ccc1S(=O)(=O)N2CCCN(CC2)S(=O)(=O)c3ccc(Cl)c(Cl)c3OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K11 compound treatment 856620.0 1270.0 0.01 1009264.0 70700.0 0.4 0.2865 0.7193 3625239 CBKinase1_014529 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2nccs2)C3c4ccccc4Oc5ccccc35 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K12 compound treatment 376418.0 -479000.0 -2.61 407633.0 -531000.0 -2.99 -3.9652 -0.9977 3625240 CBKinase1_014530 OCCCn1c(/C=C/c2cc(Br)ccc2O)nc3ccccc3c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K13 compound treatment 834596.0 -20800.0 -0.11 967541.0 28900.0 0.16 0.0352 0.1771 1652494 CBKinase1_014531 Cc1onc(c1C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3)c4ccccc4Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K14 compound treatment 835267.0 -20100.0 -0.11 911317.0 -27300.0 -0.15 -0.1863 -0.9862 1374581 CBKinase1_014532 COc1ccc(OCC(=O)Nc2sc3CCCc3c2C#N)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K15 mock treatment 788833.0 -66500.0 -0.36 750355.0 -188000.0 -1.06 -1.0071 -0.898 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K16 mock treatment 712047.0 -143000.0 -0.78 917628.0 -21000.0 -0.12 -0.6369 -0.8049 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K17 compound treatment 950283.0 94900.0 0.52 950338.0 11700.0 0.07 0.4132 0.7909 1632403 CBKinase1_014533 CCc1cc2c(=O)c(c3nc(C)cs3)c(CCC(=O)O)oc2cc1O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K18 compound treatment 804253.0 -51100.0 -0.28 848552.0 -90100.0 -0.51 -0.5562 -0.9603 3625242 CBKinase1_014534 COC(=O)c1c(C)oc2ccc(OCc3cccc(c3)[N+](=O)[O-])cc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K19 compound treatment 830774.0 -24600.0 -0.13 795947.0 -143000.0 -0.8 -0.6635 -0.8138 3625243 CBKinase1_014535 Oc1nc(CSc2nc(cc(=O)[nH]2)c3ccccc3)nc4ccccc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K20 compound treatment 754824.0 -101000.0 -0.55 928080.0 -10500.0 -0.06 -0.4301 -0.7791 3625244 CBKinase1_014536 COc1cccc(c1)c2nc(SCC(=O)Nc3cccc(c3)C(F)(F)F)[nH]c(=O)c2C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K21 compound treatment 763050.0 -92300.0 -0.5 833101.0 -106000.0 -0.59 -0.7769 -0.9966 3625245 CBKinase1_014537 [O-][N+](=O)c1ccc2[nH]c(CSc3nc4ccccc4o3)nc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K22 compound treatment 698659.0 -157000.0 -0.86 953461.0 14800.0 0.08 -0.5457 -0.6349 1266940 CBKinase1_014538 OCCN1CCN(CC(O)COc2ccc3CCCc3c2)CC1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K23 mock treatment 735886.0 -119000.0 -0.65 704695.0 -234000.0 -1.32 -1.3935 -0.9473 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 K24 mock treatment 778213.0 -77100.0 -0.42 868007.0 -70600.0 -0.4 -0.5792 -0.9996 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L01 compound treatment 882040.0 26700.0 0.15 943830.0 5220.0 0.03 0.1238 0.833 1205188 CBKinase1_014539 Cc1sc(NC(=O)COc2ccc(C)cc2)c(C(=O)N)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L02 compound treatment 327876.0 -527000.0 -2.88 340947.0 -598000.0 -3.37 -4.4183 -0.997 1525643 CBKinase1_014540 Cc1ccnc(NC(c2ccc(cc2)C(C)(C)C)c3ccc4cccnc4c3O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L03 compound treatment 867589.0 12200.0 0.07 875401.0 -63200.0 -0.36 -0.2047 -0.5647 3625246 CBKinase1_014541 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)C3COc4ccccc4O3)cc2)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L04 compound treatment 888253.0 32900.0 0.18 976106.0 37500.0 0.21 0.2764 0.9967 1361269 CBKinase1_014542 Nc1c(Cl)cc(NC(=O)CCCC(=O)O)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L05 compound treatment 883117.0 27800.0 0.15 997376.0 58800.0 0.33 0.3414 0.9372 3625247 CBKinase1_014543 Clc1ccc(NC(=O)C(=O)NCc2ccccn2)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L06 compound treatment 833461.0 -21900.0 -0.12 1008913.0 70300.0 0.4 0.1957 0.4728 3625248 CBKinase1_014544 COc1cccc(c1)N(CC(=O)Nc2ccc(C)c(Cl)c2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L07 mock treatment 883801.0 28400.0 0.16 1050969.0 112000.0 0.63 0.5576 0.8552 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L08 mock treatment 860408.0 5060.0 0.03 1009658.0 71000.0 0.4 0.3027 0.7541 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L09 compound treatment 987868.0 133000.0 0.72 1139414.0 201000.0 1.13 1.3119 0.9766 3625249 CBKinase1_014545 FC(F)(F)c1ccccc1NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L10 compound treatment 903971.0 48600.0 0.27 925080.0 -13500.0 -0.08 0.1338 0.4843 1254512 CBKinase1_014546 Cc1c(NC(=O)CN(c2cc(C)cc(C)c2)S(=O)(=O)C)c(=O)n(c3ccccc3)n1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L11 compound treatment 933234.0 77900.0 0.43 1021134.0 82500.0 0.47 0.6295 0.999 1639625 CBKinase1_014547 Fc1ccccc1NC(=O)CSc2nc3cccnc3[nH]2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L12 compound treatment 890223.0 34900.0 0.19 942298.0 3680.0 0.02 0.1493 0.7796 1668167 CBKinase1_014548 COc1ccc(cc1)N(C(C)C(=O)Nc2cc(Cl)ccc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L13 compound treatment 850212.0 -5140.0 -0.03 958026.0 19400.0 0.11 0.0575 0.5093 3625250 CBKinase1_014549 Cc1cc(C)c2oc(nc2c1)c3ccc(NC(=O)COc4ccc(cc4)[N+](=O)[O-])cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L14 compound treatment 863963.0 8610.0 0.05 986668.0 48100.0 0.27 0.2248 0.8176 3625251 CBKinase1_014550 COc1ccc(cc1)c2nnc(SCC(=O)Nc3cc(OC)ccc3OC)n2c4ccccc4C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L15 mock treatment 848028.0 -7320.0 -0.04 1004896.0 66300.0 0.37 0.2359 0.6278 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L16 mock treatment 949966.0 94600.0 0.52 843296.0 -95300.0 -0.54 -0.0146 -0.0196 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L17 compound treatment 803557.0 -51800.0 -0.28 983525.0 44900.0 0.25 -0.021 -0.0552 1217421 CBKinase1_014551 OC(=O)CCNC(=O)c1cncc(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L18 compound treatment 857313.0 1960.0 0.01 895350.0 -43300.0 -0.24 -0.1649 -0.6754 3625252 CBKinase1_014552 Cn1c(SCC(=O)n2c3CCCCc3c4ccccc24)nnc1c5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L19 compound treatment 857826.0 2470.0 0.01 953504.0 14900.0 0.08 0.0689 0.8105 1308295 CBKinase1_014553 CCOc1ccccc1Nc2nc(Nc3ccccc3OCC)nc(Sc4nnc(C)s4)n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L20 compound treatment 853763.0 -1590.0 -0.01 948645.0 10000.0 0.06 0.0338 0.5917 3625253 CBKinase1_014554 FC(F)(F)c1cc(NC(=O)CNS(=O)(=O)c2ccccc2)ccc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L21 compound treatment 1315855.0 461000.0 2.51 1379118.0 441000.0 2.48 3.5334 1.0 3625254 CBKinase1_014555 CC(=O)COc1cc(OCC(=O)C)c2c(C)cc(=O)oc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L22 compound treatment 810462.0 -44900.0 -0.25 954070.0 15500.0 0.09 -0.1117 -0.4294 3625255 CBKinase1_014556 Clc1cc(Cl)cc(NC(=O)CNS(=O)(=O)c2ccccc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L23 mock treatment 739081.0 -116000.0 -0.63 914155.0 -24500.0 -0.14 -0.5463 -0.8411 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 L24 mock treatment 906490.0 51100.0 0.28 970416.0 31800.0 0.18 0.3242 0.9771 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M01 compound treatment 864295.0 8940.0 0.05 905093.0 -33500.0 -0.19 -0.0991 -0.5077 3625256 CBKinase1_014557 COc1cc2nc(COc3ccccc3[N+](=O)[O-])oc(=O)c2cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M02 compound treatment 874298.0 18900.0 0.1 940706.0 2090.0 0.01 0.0815 0.7826 1192929 CBKinase1_014558 Cc1cc(C)c(NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4C)cc3s2)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M03 compound treatment 900963.0 45600.0 0.25 978437.0 39800.0 0.22 0.3348 0.9987 3625257 CBKinase1_014559 Clc1ccc(NC(=O)CCCN2C(=O)c3cccc4cccc(C2=O)c34)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M04 compound treatment 960160.0 105000.0 0.57 957135.0 18500.0 0.1 0.4784 0.8225 3625258 CBKinase1_014560 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)C3(CC4CC5CC(C4)CC3)C5)cc2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M05 compound treatment 965645.0 110000.0 0.6 1057065.0 118000.0 0.67 0.8979 0.9987 1357963 CBKinase1_014561 Cc1ccc(OCC(=O)Nc2ccccc2C#N)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M06 compound treatment 992895.0 138000.0 0.75 1007932.0 69300.0 0.39 0.8072 0.9537 1119229 CBKinase1_014562 CCC(Sc1nnc2c3ccccc3n(C)c2n1)C(=O)Nc4cccc5ccccc45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M07 compound treatment 927319.0 72000.0 0.39 981741.0 43100.0 0.24 0.4497 0.9734 3625259 CBKinase1_014563 Cc1ccc2NC(=O)C(O)(CC(=O)c3cccc(c3)[N+](=O)[O-])c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M08 compound treatment 933731.0 78400.0 0.43 985491.0 46900.0 0.26 0.4894 0.9732 1311293 CBKinase1_014564 Cc1cc(C)c(OCC(=O)Nc2ccccc2C#N)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M09 mock treatment 952072.0 96700.0 0.53 1051348.0 113000.0 0.64 0.8227 0.9958 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M10 mock treatment 998021.0 143000.0 0.78 1030884.0 92300.0 0.52 0.9185 0.9807 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M11 compound treatment 1014052.0 159000.0 0.87 1025957.0 87300.0 0.49 0.9608 0.9641 3625260 CBKinase1_014565 COc1ccc(cc1)c2ccc(CCC(=O)O)n2c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M12 compound treatment 949922.0 94600.0 0.52 1041045.0 102000.0 0.58 0.7733 0.9984 1722721 CBKinase1_014566 CCCn1c2ccccc2c3nnc(SCC(=O)N)nc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M13 mock treatment 1004579.0 149000.0 0.81 1025192.0 86600.0 0.49 0.9211 0.97 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M14 mock treatment 979164.0 124000.0 0.68 1052687.0 114000.0 0.64 0.9326 0.9997 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M15 compound treatment 908946.0 53600.0 0.29 1051160.0 113000.0 0.63 0.6555 0.9383 1876249 CBKinase1_014567 Cc1ccc(NC(=O)CSc2nc(N)cc(=O)[nH]2)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M16 compound treatment 968584.0 113000.0 0.62 1024036.0 85400.0 0.48 0.7776 0.9924 3625261 CBKinase1_014568 CCOC(=O)c1c(NC(=S)NC(=O)c2ccc(OC)c(c2)[N+](=O)[O-])sc3CCCc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M17 compound treatment 1041369.0 186000.0 1.02 1055980.0 117000.0 0.66 1.1859 0.9784 1541691 CBKinase1_014569 O=c1cc(nc(SCc2nc3ccccc3[nH]2)[nH]1)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M18 compound treatment 1052014.0 197000.0 1.07 1053534.0 115000.0 0.65 1.2172 0.9707 1550857 CBKinase1_014570 CC(C)Oc1ccc(NC(=O)CCN2C(=O)c3ccccc3C2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M19 compound treatment 1001327.0 146000.0 0.8 1045143.0 107000.0 0.6 0.9881 0.9903 3625262 CBKinase1_014571 CCCc1cc(=O)[nH]c(SCC(=O)Nc2ccc(C)cc2C)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M20 compound treatment 917515.0 62200.0 0.34 1022900.0 84300.0 0.48 0.5759 0.9864 3625263 CBKinase1_014572 OCCCNc1ncnc2scc(c3ccccc3)c12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M21 compound treatment 796871.0 -58500.0 -0.32 930700.0 -7910.0 -0.04 -0.2573 -0.7981 3625264 CBKinase1_014573 CCOC(=O)c1ccc(NC(=O)Cn2c(nc3ccccc23)C(F)(F)F)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M22 compound treatment 931849.0 76500.0 0.42 1028473.0 89900.0 0.51 0.6535 0.9954 1207996 CBKinase1_014574 CC1=C(C(c2cccnc2)n3ncnc3N1)C(=O)Nc4cccnc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M23 compound treatment 948319.0 93000.0 0.51 1091315.0 153000.0 0.86 0.9675 0.9683 3625265 CBKinase1_014575 Cn1c(SCCSc2nnc(c3ccccc3)n2C)nnc1c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 M24 compound treatment 1065275.0 210000.0 1.15 1003889.0 65300.0 0.37 1.0706 0.8894 1075019 CBKinase1_014576 [O-][N+](=O)c1ccc(OCC(=O)Nc2cccnc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N01 compound treatment 857120.0 1770.0 0.01 957421.0 18800.0 0.11 0.0818 0.7683 1338267 CBKinase1_014577 Cc1ccc(cc1)C(=O)CSc2nnc3c4ccccc4n(CC=C)c3n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N02 compound treatment 810514.0 -44800.0 -0.24 818864.0 -120000.0 -0.67 -0.6504 -0.9058 3625266 CBKinase1_014578 Cc1cccc(NC(c2ccc3ccc(C)nc3c2O)c4ccccc4[N+](=O)[O-])n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N03 compound treatment 881877.0 26500.0 0.14 974199.0 35600.0 0.2 0.2442 0.9872 1862849 CBKinase1_014579 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4cccc(F)c4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N04 compound treatment 928847.0 73500.0 0.4 1065391.0 127000.0 0.71 0.789 0.9628 1587171 CBKinase1_014580 COc1ccc(OCC(=O)Nc2ccc(cc2)c3nc4cc(C)ccc4o3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N05 compound treatment 936296.0 80900.0 0.44 995699.0 57100.0 0.32 0.54 0.9878 1568119 CBKinase1_014581 Cc1cc(C)c2oc(nc2c1)c3ccc(C)c(NC(=O)COc4ccc(Cl)cc4)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N06 compound treatment 961680.0 106000.0 0.58 994837.0 56200.0 0.32 0.6346 0.9595 1464958 CBKinase1_014582 Clc1ccccc1NC(=O)Cn2cnc3ccccc3c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N07 compound treatment 976166.0 121000.0 0.66 1009096.0 70500.0 0.4 0.7473 0.9706 1403499 CBKinase1_014583 CNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3cccc(O)c3)c4ccccc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N08 compound treatment 916956.0 61600.0 0.34 1052126.0 114000.0 0.64 0.6902 0.9549 1167986 CBKinase1_014584 Cc1c(NC(=O)CN(c2ccc(C)c(Cl)c2)S(=O)(=O)C)c(=O)n(c3ccccc3)n1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N09 mock treatment 917356.0 62000.0 0.34 1010594.0 72000.0 0.41 0.5262 0.9959 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N10 mock treatment 974125.0 119000.0 0.65 1013690.0 75100.0 0.42 0.7577 0.9786 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N11 compound treatment 971087.0 116000.0 0.63 1089821.0 151000.0 0.85 1.0494 0.9892 3625267 CBKinase1_014585 FC(F)(F)c1ccccc1NC(=O)CSc2nc3ccc(NC(=O)c4ccccc4)cc3s2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N12 compound treatment 946253.0 90900.0 0.5 1074471.0 136000.0 0.77 0.8924 0.978 2088710 CBKinase1_014586 [O-][N+](=O)c1ccccc1NC(=O)CC2Sc3ccccc3NC2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N13 mock treatment 916453.0 61100.0 0.33 1053641.0 115000.0 0.65 0.6943 0.9523 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N14 mock treatment 984700.0 129000.0 0.71 1032094.0 93500.0 0.53 0.8719 0.9896 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N15 compound treatment 893077.0 37700.0 0.21 1007802.0 69200.0 0.39 0.4214 0.9555 3625268 CBKinase1_014587 COc1ccc(OC)c(c1)C(=O)CCC(=O)Nc2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N16 compound treatment 920258.0 64900.0 0.35 977434.0 38800.0 0.22 0.4053 0.9732 1245193 CBKinase1_014588 Clc1ccccc1OCc2ccc(o2)C(=O)Nc3sc4CCCCc4c3C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N17 compound treatment 821026.0 -34300.0 -0.19 1015941.0 77300.0 0.44 0.1757 0.3703 1340028 CBKinase1_014589 OC(=O)c1ccc(NC(=O)CCC(=O)c2ccc(Oc3ccccc3)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N18 compound treatment 1037845.0 182000.0 1.0 1028614.0 90000.0 0.51 1.0632 0.951 3625269 CBKinase1_014590 COc1ccc(NC(=O)CN(C)S(=O)(=O)c2cc(Cl)ccc2Cl)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N19 compound treatment 939628.0 84300.0 0.46 1010041.0 71400.0 0.4 0.61 0.9978 1422290 CBKinase1_014591 Cc1ccccc1c2nc3cc(NC(=O)COc4ccc(Cl)cc4)ccc3o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N20 compound treatment 987415.0 132000.0 0.72 976383.0 37800.0 0.21 0.6604 0.8784 3625270 CBKinase1_014592 Cc1c(oc2ccccc12)C(=O)Nc3nnc(SCc4ccccc4F)s3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N21 compound treatment 977802.0 122000.0 0.67 1043144.0 105000.0 0.59 0.8893 0.998 3625271 CBKinase1_014593 OC(=O)CCc1ccc(c2ccccc2)n1c3ccc(cc3)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N22 compound treatment 899621.0 44300.0 0.24 1049181.0 111000.0 0.62 0.6116 0.9149 3625272 CBKinase1_014594 Cc1cccc(NC(=O)CSc2nnc(c3ccc(N)cc3)n2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N23 compound treatment 846664.0 -8690.0 -0.05 915069.0 -23500.0 -0.13 -0.1274 -0.9038 1467309 CBKinase1_014595 Cc1cccc(NC(c2ccccc2)c3ccc4ccc(C)nc4c3O)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 N24 compound treatment 927735.0 72400.0 0.4 968853.0 30200.0 0.17 0.4 0.9293 3625273 CBKinase1_014596 Cc1sc2ncn(CC(=O)Nc3cccc(Cl)c3C)c(=O)c2c1c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O01 compound treatment 845751.0 -9600.0 -0.05 903537.0 -35100.0 -0.2 -0.1769 -0.8647 1260588 CBKinase1_014597 Cn1cc(SCC(=O)O)c2ccccc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O02 compound treatment 759271.0 -96100.0 -0.52 897639.0 -41000.0 -0.23 -0.5342 -0.9321 3625274 CBKinase1_014598 CCOC(=O)c1ccccc1NC(=O)COc2ccccc2Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O03 compound treatment 1013321.0 158000.0 0.86 921340.0 -17300.0 -0.1 0.541 0.6233 3625275 CBKinase1_014599 Cc1cccc(OCC(=O)Nc2ccccc2C(=O)NC(C)(C)C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O04 compound treatment 827803.0 -27500.0 -0.15 986721.0 48100.0 0.27 0.0854 0.2754 3625276 CBKinase1_014600 Cn1cnnc1SCC(=O)Nc2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O05 compound treatment 890736.0 35400.0 0.19 960685.0 22100.0 0.12 0.2246 0.9773 1609519 CBKinase1_014601 COC(=O)c1ccc(COc2ccc3c(C)cc(=O)oc3c2)o1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O06 compound treatment 972957.0 118000.0 0.64 961899.0 23300.0 0.13 0.5468 0.8344 1470679 CBKinase1_014602 CN(CC(=O)O)S(=O)(=O)c1ccc2OCCOc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O07 compound treatment 860467.0 5120.0 0.03 950154.0 11500.0 0.07 0.0657 0.9287 3625277 CBKinase1_014603 OC(=O)CCc1ccc(c2cccs2)n1c3cccc(c3)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O08 compound treatment 845039.0 -10300.0 -0.06 896090.0 -42500.0 -0.24 -0.2093 -0.8501 3625278 CBKinase1_014604 [O-][N+](=O)c1ccccc1OCC(=O)Nc2ccccc2C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O09 compound treatment 922739.0 67400.0 0.37 900516.0 -38100.0 -0.21 0.1083 0.2542 1692809 CBKinase1_014605 COc1cc(OC)cc(c1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O10 compound treatment 817032.0 -38300.0 -0.21 901618.0 -37000.0 -0.21 -0.2954 -1.0 1407440 CBKinase1_014606 COc1cc(SC)ccc1C(=O)NCCc2c[nH]c3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O11 mock treatment 717714.0 -138000.0 -0.75 951876.0 13300.0 0.07 -0.4785 -0.6336 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O12 mock treatment 906655.0 51300.0 0.28 954922.0 16300.0 0.09 0.263 0.8923 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O13 compound treatment 904249.0 48900.0 0.27 960417.0 21800.0 0.12 0.2757 0.938 3625279 CBKinase1_014607 COc1ccccc1CC(=O)Nc2ccc(cc2)S(=O)(=O)N3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O14 compound treatment 841529.0 -13800.0 -0.08 983287.0 44700.0 0.25 0.1247 0.4743 3625280 CBKinase1_014608 O=C(CCn1[nH]c(=O)c2ccccc2c1=O)NCc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O15 compound treatment 878094.0 22700.0 0.12 929288.0 -9330.0 -0.05 0.0506 0.3755 3625281 CBKinase1_014609 Cc1ccc(NC(=O)CSc2nc(cc(=O)[nH]2)c3ccccc3)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O16 compound treatment 809053.0 -46300.0 -0.25 1037387.0 98800.0 0.56 0.2149 0.3515 3625282 CBKinase1_014610 Oc1ccc(C(=O)CON2C(=O)c3ccccc3C2=O)c(O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O17 compound treatment 785983.0 -69400.0 -0.38 926412.0 -12200.0 -0.07 -0.3164 -0.8221 1667126 CBKinase1_014611 Nc1cc(=O)[nH]c(SCC(=O)NCc2ccco2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O18 compound treatment 805883.0 -49500.0 -0.27 907473.0 -31100.0 -0.18 -0.3151 -0.9782 3625283 CBKinase1_014612 NC(=O)C1CCN(CC(=O)Nc2ccccc2C#N)CC1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O19 compound treatment 941371.0 86000.0 0.47 1016965.0 78400.0 0.44 0.6443 0.9995 3625284 CBKinase1_014613 Oc1nc(CSc2nnc(c3ccccc3)n2c4ccccc4)nc5ccccc15 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O20 compound treatment 875005.0 19700.0 0.11 1000409.0 61800.0 0.35 0.3222 0.8839 3625285 CBKinase1_014614 COc1ccccc1C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nc(C)cc(C)n3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O21 compound treatment 829608.0 -25700.0 -0.14 944174.0 5560.0 0.03 -0.0772 -0.5363 1687543 CBKinase1_014615 CCOC(=O)c1sc(nc1C)N2C(C(=C(O)C2=O)C(=O)c3ccc(C)cc3)c4ccc(C)o4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O22 compound treatment 798303.0 -57000.0 -0.31 1025001.0 86400.0 0.49 0.1241 0.2146 1661966 CBKinase1_014616 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)C3COc4ccccc4O3)cc2)nc(C)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O23 compound treatment 781440.0 -73900.0 -0.4 930847.0 -7770.0 -0.04 -0.3163 -0.7792 3625286 CBKinase1_014617 Cc1ccc(CN(CC(=O)N)S(=O)(=O)c2ccc(Cl)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 O24 compound treatment 847295.0 -8060.0 -0.04 948919.0 10300.0 0.06 0.01 0.1368 1681640 CBKinase1_014618 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)C3COc4ccccc4O3)cc2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P01 compound treatment 816869.0 -38500.0 -0.21 842849.0 -95800.0 -0.54 -0.5302 -0.9154 3625287 CBKinase1_014619 [O-][N+](=O)c1ccc(NC(=S)NCCCn2ccnc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P02 compound treatment 713065.0 -142000.0 -0.78 866682.0 -71900.0 -0.41 -0.836 -0.954 3625288 CBKinase1_014620 COc1cc2c(cc1NC(=O)C(C)Oc3ccc(Cl)cc3Cl)oc4ccccc42 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P03 compound treatment 806187.0 -49200.0 -0.27 878129.0 -60500.0 -0.34 -0.4309 -0.993 3625289 CBKinase1_014621 COC(=O)C(NC(=O)c1ccc(o1)[N+](=O)[O-])C(C)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P04 compound treatment 748826.0 -107000.0 -0.58 933277.0 -5340.0 -0.03 -0.4325 -0.7427 3625290 CBKinase1_014622 COc1ccc(Cl)cc1N(CC(=O)Nc2ccccc2C(F)(F)F)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P05 compound treatment 843747.0 -11600.0 -0.06 905904.0 -32700.0 -0.18 -0.1752 -0.8985 3625291 CBKinase1_014623 Cc1cc(C)cc(OCC(=O)Nc2cc(ccc2C)c3nc4cc(Cl)ccc4o3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P06 compound treatment 549497.0 -306000.0 -1.67 583020.0 -356000.0 -2.0 -2.598 -0.9959 1178310 CBKinase1_014624 COc1ccc(cc1OC)C(NC(=O)c2cccnc2)c3cc(Cl)c4cccnc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P07 compound treatment 785299.0 -70100.0 -0.38 906895.0 -31700.0 -0.18 -0.3969 -0.94 3625292 CBKinase1_014625 Cc1ccc(NC(=O)CN(c2ccc(Cl)c(c2)C(F)(F)F)S(=O)(=O)C)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P08 compound treatment 832123.0 -23200.0 -0.13 869646.0 -69000.0 -0.39 -0.3645 -0.8915 3625293 CBKinase1_014626 COc1ccc(C)cc1N(CC(=O)Nc2ccccc2C(F)(F)F)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P09 compound treatment 744171.0 -111000.0 -0.61 877500.0 -61100.0 -0.34 -0.6728 -0.964 3625294 CBKinase1_014627 COc1ccc(NC(=O)COc2ccc(cc2)[N+](=O)[O-])c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P10 compound treatment 771787.0 -83600.0 -0.46 892090.0 -46500.0 -0.26 -0.508 -0.9654 3625295 CBKinase1_014628 CS(=O)(=O)N(CC(=O)NC1CC1)c2cccc(c2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P11 mock treatment 759607.0 -95700.0 -0.52 916249.0 -22400.0 -0.13 -0.4588 -0.8532 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P12 mock treatment 743601.0 -112000.0 -0.61 961951.0 23300.0 0.13 -0.3384 -0.5422 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P13 compound treatment 781657.0 -73700.0 -0.4 933194.0 -5420.0 -0.03 -0.3061 -0.7586 1380318 CBKinase1_014629 COc1cc(NC(=O)COc2ccccc2Br)c(OC)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P14 compound treatment 865231.0 9880.0 0.05 956471.0 17900.0 0.1 0.1093 0.9572 3625296 CBKinase1_014630 COc1ccc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)Nc3ccc(OC)cc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P15 compound treatment 864780.0 9430.0 0.05 932792.0 -5820.0 -0.03 0.0132 0.2161 3625297 CBKinase1_014631 Cc1cc2nc(oc2cc1C)c3ccc(NC(=O)COc4ccc(cc4)[N+](=O)[O-])cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P16 compound treatment 806154.0 -49200.0 -0.27 901083.0 -37500.0 -0.21 -0.3395 -0.993 3625298 CBKinase1_014632 CN1CCN(CC(=O)Nc2ccc(cc2C(=O)c3ccccc3)[N+](=O)[O-])CC1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P17 compound treatment 717240.0 -138000.0 -0.75 886903.0 -51700.0 -0.29 -0.7393 -0.9145 1384670 CBKinase1_014633 Clc1ccc(OCC(=O)Nc2cccc(c2)c3nc4ncccc4o3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P18 compound treatment 774337.0 -81000.0 -0.44 987439.0 48800.0 0.28 -0.1182 -0.2268 1124213 CBKinase1_014634 CCOC(=O)c1c(NC(=O)C2(CCC3(C)C(=O)O2)C3(C)C)sc4CCCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P19 compound treatment 822436.0 -32900.0 -0.18 999795.0 61200.0 0.34 0.1168 0.3003 1484621 CBKinase1_014635 CCC(Sc1nnc2c3ccccc3[nH]c2n1)C(=O)N4c5ccccc5Sc6ccccc46 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P20 compound treatment 827410.0 -27900.0 -0.15 910540.0 -28100.0 -0.16 -0.2198 -0.9998 1365728 CBKinase1_014636 COc1ccccc1OCc2ccc(o2)C(=O)n3nc(C)c(Cl)c3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P21 compound treatment 887602.0 32300.0 0.18 954076.0 15500.0 0.09 0.1861 0.9474 1545482 CBKinase1_014637 COC(=O)c1ccccc1n2c(CCC(=O)O)ccc2c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P22 compound treatment 820497.0 -34900.0 -0.19 999547.0 60900.0 0.34 0.1083 0.2758 3625299 CBKinase1_014638 CC(=O)c1ccccc1OC(=O)CCN2C(=O)C3C(C4C=CC3C5CC54)C2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P23 compound treatment 369812.0 -486000.0 -2.65 378124.0 -560000.0 -3.16 -4.1083 -0.9962 1186947 CBKinase1_014639 Oc1c(ccc2cccnc12)C(Nc3ccccn3)c4ccc(Cl)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2369 P24 compound treatment 816684.0 -38700.0 -0.21 890171.0 -48400.0 -0.27 -0.3423 -0.9919 3625300 CBKinase1_014640 COc1ccccc1CC(=O)Nc2cc(OC)c(OC)cc2C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A01 compound treatment 966286.0 10500.0 0.06 409012.0 -82100.0 -0.46 -0.2867 -0.6144 3625301 CBKinase1_014641 COc1ccc(cc1OC)C(=O)Nc2ccc3nc(SCC(=O)Nc4ccccc4F)sc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A02 compound treatment 797562.0 -158000.0 -0.86 589938.0 98800.0 0.56 -0.2169 -0.2111 1615894 CBKinase1_014642 Cc1cc2NC(CC(=O)Nc3ccc(cc3)N4CCOCC4)C(=O)Nc2cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A03 compound treatment 887851.0 -67900.0 -0.37 309404.0 -182000.0 -1.02 -0.9864 -0.9055 3625302 CBKinase1_014643 CCC(Sc1nnc(c2ccc(cc2)[N+](=O)[O-])n1C)C(=O)Nc3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A04 compound treatment 1026129.0 70400.0 0.38 354507.0 -137000.0 -0.77 -0.2729 -0.317 1786616 CBKinase1_014644 COc1ccc(cc1Cl)N(CC(=O)Nc2ccccc2F)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A05 compound treatment 1042120.0 86400.0 0.47 472783.0 -18400.0 -0.1 0.2603 0.5391 3625303 CBKinase1_014645 [O-][N+](=O)c1ccc(cc1)c2nnc(SCC(=O)N3CCOCC3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A06 compound treatment 734793.0 -221000.0 -1.21 242160.0 -249000.0 -1.4 -1.8453 -0.9972 1361139 CBKinase1_014646 COc1cccc(c1)C(=O)NC(c2ccccc2OC)c3c(O)ccc4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A07 compound treatment 1015667.0 59900.0 0.33 324097.0 -167000.0 -0.94 -0.4345 -0.4358 1746665 CBKinase1_014647 COC(=O)c1ccc(NC(=O)CSc2nnc(C)s2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A08 compound treatment 988334.0 32600.0 0.18 352084.0 -139000.0 -0.78 -0.4284 -0.533 1450476 CBKinase1_014648 COc1ccc(Cl)cc1S(=O)(=O)Nc2ccc(Cl)cn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A09 compound treatment 904022.0 -51700.0 -0.28 413995.0 -77200.0 -0.43 -0.5072 -0.9781 3625304 CBKinase1_014649 Brc1ccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccccc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A10 compound treatment 847150.0 -109000.0 -0.59 344834.0 -146000.0 -0.82 -1.0024 -0.9869 3625305 CBKinase1_014650 COc1ccc(cc1[N+](=O)[O-])C(=O)NC(=S)NCc2cccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A11 compound treatment 791162.0 -165000.0 -0.9 391088.0 -100000.0 -0.56 -1.0341 -0.9748 3625306 CBKinase1_014651 O=C(CCN1C(=O)C2C(C3C=CC2C4CC43)C1=O)Oc5cccc6cccnc56 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A12 compound treatment 943625.0 -12100.0 -0.07 389864.0 -101000.0 -0.57 -0.4504 -0.7838 3625307 CBKinase1_014652 CS(=O)(=O)N(CC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F)c2cccc(c2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A13 mock treatment 853256.0 -102000.0 -0.56 379670.0 -111000.0 -0.63 -0.8399 -0.9983 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A14 mock treatment 802547.0 -153000.0 -0.84 310696.0 -180000.0 -1.02 -1.3106 -0.9953 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A15 compound treatment 961903.0 6160.0 0.03 340003.0 -151000.0 -0.85 -0.5786 -0.6787 3625308 CBKinase1_014653 Cc1ccc(NC(=O)CNS(=O)(=O)c2ccccc2)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A16 compound treatment 1005217.0 49500.0 0.27 332297.0 -159000.0 -0.9 -0.4421 -0.4727 3625309 CBKinase1_014654 Brc1ccc(OC(=O)C(Cc2ccccc2)N3C(=O)C4C5CCC(C5)C4C3=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A17 compound treatment 1034198.0 78500.0 0.43 500240.0 9090.0 0.05 0.3391 0.7861 3625310 CBKinase1_014655 Cn1c(Cc2cccc3ccccc23)nnc1SCC(=O)c4ccc(Cl)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A18 compound treatment 886827.0 -68900.0 -0.38 349486.0 -142000.0 -0.8 -0.8306 -0.9411 3625311 CBKinase1_014656 CCOC(=O)CSc1nnc(c2ccc(OC)cc2)n1c3ccccc3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A19 compound treatment 899302.0 -56400.0 -0.31 560638.0 69500.0 0.39 0.0591 0.1185 2062072 CBKinase1_014657 COc1ccccc1NC(=O)CSc2ccccn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A20 compound treatment 809690.0 -146000.0 -0.8 356692.0 -134000.0 -0.76 -1.0997 -0.9997 3625312 CBKinase1_014658 Cc1cc(Cl)ccc1NC(=O)CSc2nc(cc(=O)[nH]2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A21 compound treatment 958829.0 3090.0 0.02 267644.0 -224000.0 -1.26 -0.8789 -0.6976 3625313 CBKinase1_014659 CC1=C(C(C(=C(N1)SCC(=O)c2ccc(Cl)cc2)C#N)c3ccco3)C(=O)Nc4ccccc4F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A22 compound treatment 881124.0 -74600.0 -0.41 550906.0 59800.0 0.34 -0.0499 -0.0944 3625314 CBKinase1_014660 Cn1c(SCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)nnc1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A23 compound treatment 794612.0 -161000.0 -0.88 412729.0 -78400.0 -0.44 -0.9346 -0.9493 3625315 CBKinase1_014661 Brc1ccc(NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 A24 compound treatment 1156671.0 201000.0 1.1 414665.0 -76500.0 -0.43 0.4709 0.3995 3625316 CBKinase1_014662 CCOC(=O)c1c(NC(=O)c2ccc(Cn3cc(Cl)cn3)o2)sc4CCCCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B01 compound treatment 956209.0 468.0 0.0 342308.0 -149000.0 -0.84 -0.5914 -0.705 3625317 CBKinase1_014663 OC(=O)CCC(=O)Nc1ccc(Br)c2cccnc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B02 compound treatment 873327.0 -82400.0 -0.45 407335.0 -83800.0 -0.47 -0.6522 -0.9997 3625318 CBKinase1_014664 COc1cc(NC(=O)COc2cc(C)c(Br)c(C)c2)c(OC)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B03 compound treatment 959568.0 3830.0 0.02 488183.0 -2970.0 -0.02 0.003 0.1103 1591553 CBKinase1_014665 COc1ccc(OC)c(c1)C2N(CCN3CCOCC3)C(=O)C(=C2C(=O)c4ccco4)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B04 compound treatment 971627.0 15900.0 0.09 363430.0 -128000.0 -0.72 -0.4477 -0.6175 3625319 CBKinase1_014666 CCC(Sc1nnnn1c2ccccc2)C(=O)Nc3ccc(cc3)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B05 compound treatment 949426.0 -6320.0 -0.03 471019.0 -20100.0 -0.11 -0.1046 -0.8822 1946544 CBKinase1_014667 COc1ccc(NC(=O)CSc2nc(C)cc(C)n2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B06 compound treatment 1041365.0 85600.0 0.47 354899.0 -136000.0 -0.77 -0.2125 -0.2363 3625320 CBKinase1_014668 CCc1ccccc1NC(=O)CN(C)S(=O)(=O)c2ccc(Br)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B07 compound treatment 947621.0 -8120.0 -0.04 480713.0 -10400.0 -0.06 -0.0729 -0.9903 1329438 CBKinase1_014669 Cc1cccc(NC(=O)CN(c2ccc(Oc3ccccc3)cc2)S(=O)(=O)C)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B08 compound treatment 857300.0 -98400.0 -0.54 405440.0 -85700.0 -0.48 -0.7216 -0.9986 3625321 CBKinase1_014670 Cc1ccc(NC(=O)C(Cc2ccccc2)N3C(=O)C4C5CCC(C5)C4C3=O)cc1[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B09 compound treatment 920549.0 -35200.0 -0.19 443738.0 -47400.0 -0.27 -0.3248 -0.9869 1428422 CBKinase1_014671 COc1ccc(C)cc1NC(=O)CN(c2ccc(I)cc2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B10 compound treatment 1078207.0 122000.0 0.67 316768.0 -174000.0 -0.98 -0.2222 -0.1869 3625322 CBKinase1_014672 CN(CC(=O)Nc1ccc(cc1)C(=O)O)S(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B11 compound treatment 927323.0 -28400.0 -0.16 374858.0 -116000.0 -0.66 -0.5732 -0.851 3625323 CBKinase1_014673 Cc1cc(C)nc(SCc2noc(n2)c3ccc(Cl)cc3)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B12 compound treatment 929666.0 -26100.0 -0.14 344590.0 -147000.0 -0.83 -0.6848 -0.8169 3625324 CBKinase1_014674 O=C(NCc1ccco1)c2cccc(c2)S(=O)(=O)N3CCCCCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B13 mock treatment 946945.0 -8800.0 -0.05 338648.0 -153000.0 -0.86 -0.6418 -0.7455 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B14 mock treatment 984759.0 29000.0 0.16 469877.0 -21300.0 -0.12 0.0272 0.1371 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B15 compound treatment 964126.0 8380.0 0.05 444790.0 -46400.0 -0.26 -0.1524 -0.5745 3625325 CBKinase1_014675 CCOc1ccccc1NC(=O)c2c(NC(=O)CN3CCOCC3)sc4CCCc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B16 compound treatment 999355.0 43600.0 0.24 463323.0 -27800.0 -0.16 0.0575 0.2016 3625326 CBKinase1_014676 Cc1cccc(N(CC(=O)NC2CCCCCC2)S(=O)(=O)C)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B17 compound treatment 828264.0 -127000.0 -0.7 376817.0 -114000.0 -0.64 -0.9478 -0.9993 1870562 CBKinase1_014677 CCNC(=O)c1c(NC(=O)c2ccccc2[N+](=O)[O-])sc3CCCCc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B18 compound treatment 954573.0 -1170.0 -0.01 342834.0 -148000.0 -0.84 -0.5956 -0.7125 3625327 CBKinase1_014678 COc1ccc(Cl)cc1NC(=O)CN(c2ccc(I)cc2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B19 compound treatment 963194.0 7450.0 0.04 601359.0 110000.0 0.62 0.468 0.7518 3625328 CBKinase1_014679 Brc1ccc(cc1)C(=O)Nc2sc3CCCCc3c2C(=O)NCc4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B20 compound treatment 892144.0 -63600.0 -0.35 433032.0 -58100.0 -0.33 -0.4771 -0.9996 1355172 CBKinase1_014680 Clc1cccc(NC(=O)CSc2nc3ccccc3[nH]2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B21 compound treatment 972555.0 16800.0 0.09 506875.0 15700.0 0.09 0.1276 0.9998 3625329 CBKinase1_014681 Fc1ccc(OCC(=O)Nc2sc3CCCCc3c2C(=O)NC4CCS(=O)(=O)C4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B22 compound treatment 857341.0 -98400.0 -0.54 615590.0 124000.0 0.7 0.1161 0.1314 1416829 CBKinase1_014682 Cc1cccc(C)c1NC(=O)C2CC=CCC2C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B23 compound treatment 875951.0 -79800.0 -0.44 360551.0 -131000.0 -0.74 -0.8285 -0.9687 3625330 CBKinase1_014683 COc1cccc(OCCNS(=O)(=O)c2cccc(c2)[N+](=O)[O-])c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 B24 compound treatment 898398.0 -57300.0 -0.31 433053.0 -58100.0 -0.33 -0.4529 -0.9997 1733133 CBKinase1_014684 OCc1nc2ccccc2n1CCOc3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C01 compound treatment 971129.0 15400.0 0.08 333719.0 -157000.0 -0.89 -0.568 -0.6373 3625331 CBKinase1_014685 Cc1sc2ncn(CC(=O)NCc3ccco3)c(=O)c2c1c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C02 compound treatment 993259.0 37500.0 0.2 308541.0 -183000.0 -1.03 -0.583 -0.5555 1439272 CBKinase1_014686 Cc1ccc(cc1)c2nn(CC(=O)Nc3ccc(C)cc3C)c(=O)c4ccccc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C03 compound treatment 1029406.0 73700.0 0.4 344617.0 -147000.0 -0.83 -0.2996 -0.3262 3625332 CBKinase1_014687 CCn1c(SCC(=O)Nc2ccc(Cl)c(Cl)c2)nnc1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C04 compound treatment 1041157.0 85400.0 0.47 299947.0 -191000.0 -1.08 -0.4323 -0.3681 3625333 CBKinase1_014688 CC(=O)Nc1nonc1c2nc3ccccc3n2Cc4ccc(Cl)cc4Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C05 compound treatment 1065222.0 109000.0 0.6 607153.0 116000.0 0.65 0.885 0.999 1208277 CBKinase1_014689 Brc1ccc2oc(=O)c(cc2c1)C(=O)NCc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C06 compound treatment 979784.0 24000.0 0.13 479066.0 -12100.0 -0.07 0.0447 0.302 1624023 CBKinase1_014690 Clc1ccc(c(Cl)c1Cl)S(=O)(=O)NCc2cccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C07 compound treatment 914267.0 -41500.0 -0.23 549701.0 58600.0 0.33 0.0733 0.183 3625334 CBKinase1_014691 Cc1ccccc1NC(=O)CSc2nnc(c3ccc(cc3)[N+](=O)[O-])n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C08 compound treatment 1149494.0 194000.0 1.06 528468.0 37300.0 0.21 0.8967 0.8314 3625335 CBKinase1_014692 CS(=O)(=O)N(CC(=O)NC1CC2CCC1C2)c3ccc(Cl)c(c3)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C09 compound treatment 1040192.0 84500.0 0.46 516361.0 25200.0 0.14 0.4265 0.884 3625336 CBKinase1_014693 COC(=O)c1ccc(NC(=O)CN(C)S(=O)(=O)c2cc(Cl)ccc2Cl)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C10 compound treatment 926325.0 -29400.0 -0.16 322702.0 -168000.0 -0.95 -0.7849 -0.8151 3625337 CBKinase1_014694 Cc1cc(Cl)ccc1NC(=O)CN(c2cccc(Cl)c2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C11 mock treatment 865761.0 -90000.0 -0.49 421223.0 -69900.0 -0.39 -0.6261 -0.994 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C12 mock treatment 1104277.0 149000.0 0.81 547016.0 55900.0 0.31 0.7961 0.9151 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C13 compound treatment 1012677.0 56900.0 0.31 355842.0 -135000.0 -0.76 -0.3195 -0.3879 1713874 CBKinase1_014695 CC(=O)Nc1ccc(Nc2ncnc3n(ncc23)c4ccc(C)cc4C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C14 compound treatment 1046782.0 91000.0 0.5 340200.0 -151000.0 -0.85 -0.2502 -0.2539 1424628 CBKinase1_014696 NS(=O)(=O)c1ccc(NC(=S)NCCN2CCOCC2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C15 mock treatment 963921.0 8180.0 0.04 373259.0 -118000.0 -0.66 -0.4383 -0.6581 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C16 mock treatment 814012.0 -142000.0 -0.77 344629.0 -147000.0 -0.83 -1.1311 -0.9995 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C17 compound treatment 1025590.0 69800.0 0.38 356757.0 -134000.0 -0.76 -0.266 -0.3136 3625338 CBKinase1_014697 Clc1ccccc1c2nc(C#N)c(NCCCN3CCOCC3)o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C18 compound treatment 798470.0 -157000.0 -0.86 560847.0 69700.0 0.39 -0.3294 -0.3488 3625339 CBKinase1_014698 CC(C)(C)c1ccc(cc1)C(=O)N2CCN(CC2)c3ccc([N+](=O)[O-])c(NCc4cccnc4)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C19 compound treatment 937038.0 -18700.0 -0.1 321100.0 -170000.0 -0.96 -0.7499 -0.778 3625340 CBKinase1_014699 CCOc1ccccc1OCC(=O)Nc2ccccc2[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C20 compound treatment 833361.0 -122000.0 -0.67 558024.0 66900.0 0.38 -0.2059 -0.2684 3625341 CBKinase1_014700 COc1ccccc1NC(=O)CSc2nnc(c3ccc(cc3)[N+](=O)[O-])n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C21 compound treatment 947793.0 -7950.0 -0.04 456968.0 -34200.0 -0.19 -0.1669 -0.8452 3625342 CBKinase1_014701 Cc1cccc(OCC(=O)Nc2c[nH]c(=O)[nH]c2=O)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C22 compound treatment 844633.0 -111000.0 -0.61 328529.0 -163000.0 -0.92 -1.0771 -0.9799 3625343 CBKinase1_014702 CC(=O)Nc1ccc(cc1)c2nnc(SCC(=O)NC3CCCCC3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C23 compound treatment 922373.0 -33400.0 -0.18 421095.0 -70100.0 -0.39 -0.408 -0.9383 3625344 CBKinase1_014703 [O-][N+](=O)c1ccc(cc1)c2nnc(SCC(=O)NC3CCCCC3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 C24 compound treatment 986419.0 30700.0 0.17 299020.0 -192000.0 -1.08 -0.6473 -0.5907 3625345 CBKinase1_014704 Cc1nnc(SCC(=O)Nc2ccc(C)cc2C)s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D01 compound treatment 990141.0 34400.0 0.19 256943.0 -234000.0 -1.32 -0.8006 -0.6005 3625346 CBKinase1_014705 COc1ccc(OCC(=O)Nc2cccc(C(=O)O)c2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D02 compound treatment 1011399.0 55700.0 0.3 298280.0 -193000.0 -1.09 -0.5538 -0.4906 3625347 CBKinase1_014706 CC(=O)Nc1ccccc1NC(=O)COc2cc(C)c(Br)c(C)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D03 compound treatment 1016069.0 60300.0 0.33 455183.0 -36000.0 -0.2 0.0895 0.2315 1586995 CBKinase1_014707 Cc1ccc(OCC(=O)NC(=S)Nc2cc(ccc2Cl)c3nc4ncccc4o3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D04 compound treatment 966384.0 10600.0 0.06 315555.0 -176000.0 -0.99 -0.6588 -0.6645 3625348 CBKinase1_014708 COc1cc2c(cc1NC(=O)CSc3ccccn3)oc4ccccc42 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D05 compound treatment 1136458.0 181000.0 0.99 370779.0 -120000.0 -0.68 0.2179 0.182 3625349 CBKinase1_014709 CS(=O)(=O)N(CC(=O)NC1CCCCCC1)c2ccc(I)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D06 compound treatment 1090429.0 135000.0 0.74 395856.0 -95300.0 -0.54 0.1402 0.1539 1983926 CBKinase1_014710 OC(C(CC(=O)O)C(=O)O)c1ccccc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D07 compound treatment 1046016.0 90300.0 0.49 401567.0 -89600.0 -0.5 -0.0085 -0.0121 3625350 CBKinase1_014711 CS(=O)(=O)N(CC(=O)Nc1cccc(c1)[N+](=O)[O-])c2ccc(Br)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D08 compound treatment 928927.0 -26800.0 -0.15 587911.0 96800.0 0.55 0.2821 0.4996 3625351 CBKinase1_014712 O=C(NCc1ccco1)c2ccc3nc(c4cccs4)c(nc3c2)c5cccs5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D09 compound treatment 1104794.0 149000.0 0.81 503481.0 12300.0 0.07 0.6246 0.7647 3625352 CBKinase1_014713 CS(=O)(=O)N(CC(=O)Nc1ccc(Cl)cc1)c2cccc(c2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D10 compound treatment 1009656.0 53900.0 0.29 542820.0 51700.0 0.29 0.4141 1.0 1322776 CBKinase1_014714 Cc1ccccc1OCC(=O)NCC(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D11 mock treatment 1081930.0 126000.0 0.69 446928.0 -44200.0 -0.25 0.3109 0.4244 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D12 mock treatment 1119249.0 164000.0 0.89 523095.0 31900.0 0.18 0.7585 0.833 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D13 compound treatment 986014.0 30300.0 0.17 460399.0 -30700.0 -0.17 -0.0057 -0.0238 3625353 CBKinase1_014715 Cc1cccc(NC(=O)CSc2nc3ccccc3c(=O)n2C)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D14 compound treatment 988012.0 32300.0 0.18 401864.0 -89300.0 -0.5 -0.2313 -0.4337 3625354 CBKinase1_014716 Cc1ncc([N+](=O)[O-])n1CC(=O)Nc2ccc(F)c(Cl)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D15 mock treatment 1140844.0 185000.0 1.01 467218.0 -23900.0 -0.13 0.6192 0.6073 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D16 mock treatment 1036054.0 80300.0 0.44 401401.0 -89700.0 -0.51 -0.0477 -0.0712 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D17 compound treatment 1115979.0 160000.0 0.87 526208.0 35100.0 0.2 0.7583 0.8455 3625355 CBKinase1_014717 Cn1c(SCC(=O)Nc2ccccc2[N+](=O)[O-])nc3ccccc3c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D18 compound treatment 1049324.0 93600.0 0.51 459478.0 -31700.0 -0.18 0.235 0.4343 1436485 CBKinase1_014718 COc1cc(cc(OC)c1OC)C(=O)NCc2ccco2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D19 compound treatment 986113.0 30400.0 0.17 348513.0 -143000.0 -0.8 -0.4512 -0.5497 3625356 CBKinase1_014719 COc1ccc(cc1OC)c2nnc(SCC(=O)c3ccc(cc3)c4ccccc4)o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D20 compound treatment 1018337.0 62600.0 0.34 321667.0 -169000.0 -0.96 -0.4338 -0.4276 1007509 CBKinase1_014720 OC(=O)CCCC(=O)Nc1ccccc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D21 compound treatment 943619.0 -12100.0 -0.07 346503.0 -145000.0 -0.82 -0.6233 -0.762 3625357 CBKinase1_014721 Cc1cc(OCC(=O)NCc2ccco2)cc(C)c1Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D22 compound treatment 980160.0 24400.0 0.13 523310.0 32200.0 0.18 0.2224 0.9886 3625358 CBKinase1_014722 Cc1cccc(NC(=O)CN(c2ccc(Cl)cc2C)S(=O)(=O)C)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D23 compound treatment 905730.0 -50000.0 -0.27 321469.0 -170000.0 -0.96 -0.8693 -0.8741 3625359 CBKinase1_014723 C=CCNC(=O)c1c(NC(=O)C2COc3ccccc3O2)sc4CCCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 D24 compound treatment 947040.0 -8700.0 -0.05 472107.0 -19000.0 -0.11 -0.1095 -0.9328 3625360 CBKinase1_014724 Clc1cccc(NC(=O)C(=O)NCc2cccnc2)c1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E01 mock treatment 875664.0 -80100.0 -0.44 607775.0 117000.0 0.66 0.1557 0.1972 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E02 mock treatment 833600.0 -122000.0 -0.67 495342.0 4190.0 0.02 -0.4548 -0.6816 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E03 compound treatment 838136.0 -118000.0 -0.64 632131.0 141000.0 0.79 0.1079 0.1056 1984077 CBKinase1_014725 COC(=O)Cc1cc(O)n(n1)c2nc3ccccc3s2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E04 compound treatment 949370.0 -6370.0 -0.03 634090.0 143000.0 0.81 0.5451 0.6759 3625361 CBKinase1_014726 COc1ccc(CSCC(N)C(=O)O)cc1Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E05 compound treatment 938730.0 -17000.0 -0.09 470243.0 -20900.0 -0.12 -0.149 -0.9931 3625362 CBKinase1_014727 Clc1ccc(NC(=O)CSc2nnc(o2)c3ccc(Br)cc3)c(Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E06 compound treatment 919668.0 -36100.0 -0.2 484569.0 -6580.0 -0.04 -0.1655 -0.8257 3625363 CBKinase1_014728 COc1ccc(NC(=O)CN(C)S(=O)(=O)c2cc(Cl)ccc2Cl)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E07 compound treatment 1018374.0 62600.0 0.34 543176.0 52000.0 0.29 0.4491 0.9971 3625364 CBKinase1_014729 Cn1c(SCC(=O)Nc2ccccc2F)nnc1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E08 compound treatment 916791.0 -39000.0 -0.21 509827.0 18700.0 0.11 -0.0759 -0.32 3625365 CBKinase1_014730 COc1ccc(C)cc1NC(=O)CN(c2ccc(F)cc2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E09 mock treatment 896427.0 -59300.0 -0.32 598519.0 107000.0 0.61 0.1989 0.2899 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E10 mock treatment 750063.0 -206000.0 -1.12 435427.0 -55700.0 -0.31 -1.0161 -0.8714 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E11 compound treatment 966702.0 11000.0 0.06 424095.0 -67100.0 -0.38 -0.2249 -0.5878 1518251 CBKinase1_014731 CCc1c(C)sc(NC(=O)c2ccc(Cn3nc(C)c(Cl)c3C)o2)c1C(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E12 compound treatment 817735.0 -138000.0 -0.75 555918.0 64800.0 0.37 -0.2746 -0.328 1491827 CBKinase1_014732 Cn1nc(CC(=O)Nc2ccc(OC(=O)c3ccccc3)cc2)c4ccccc4c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E13 compound treatment 908491.0 -47300.0 -0.26 643349.0 152000.0 0.86 0.4242 0.4735 3625366 CBKinase1_014733 COc1ccc(Cl)cc1NC(=O)CSc2nnc(c3ccccc3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E14 compound treatment 907704.0 -48000.0 -0.26 595668.0 105000.0 0.59 0.2311 0.3584 3625367 CBKinase1_014734 O=C(Nc1ccccc1C(=O)Nc2ccccc2C(=O)NCc3ccco3)c4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E15 compound treatment 921671.0 -34100.0 -0.19 423662.0 -67500.0 -0.38 -0.4005 -0.9459 3625368 CBKinase1_014735 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2c(C)nn(c2C)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E16 compound treatment 894679.0 -61100.0 -0.33 507438.0 16300.0 0.09 -0.1708 -0.494 1984236 CBKinase1_014736 Brc1ccc(NC(=O)CC2Sc3ncnn3C2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E17 mock treatment 957659.0 1920.0 0.01 489125.0 -2020.0 -0.01 -7.0E-4 -0.0428 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E18 mock treatment 799999.0 -156000.0 -0.85 595228.0 104000.0 0.59 -0.1864 -0.1805 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E19 compound treatment 897570.0 -58200.0 -0.32 527701.0 36600.0 0.21 -0.0789 -0.2084 3625369 CBKinase1_014737 Cc1ccc(NC(=O)CSc2nnc(c3ccc(cc3)[N+](=O)[O-])n2c4ccccc4)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E20 compound treatment 809913.0 -146000.0 -0.8 576832.0 85700.0 0.48 -0.2215 -0.2378 3625370 CBKinase1_014738 N#Cc1ccccc1CSc2nnc(c3ccccc3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E21 compound treatment 827208.0 -129000.0 -0.7 391807.0 -99300.0 -0.56 -0.8921 -0.9937 3625371 CBKinase1_014739 COc1ccccc1n2c(N)cc(=O)nc2SCC(=O)Nc3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E22 compound treatment 646745.0 -309000.0 -1.69 428767.0 -62400.0 -0.35 -1.4415 -0.8365 3118134 CBKinase1_014740 Cc1cc(nn1Cc2ccc(o2)C(=O)NCc3ccco3)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E23 compound treatment 732590.0 -223000.0 -1.22 389504.0 -102000.0 -0.57 -1.2666 -0.9408 3625372 CBKinase1_014741 Fc1cc(Br)ccc1NC(=O)CNS(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 E24 compound treatment 776587.0 -179000.0 -0.98 439804.0 -51300.0 -0.29 -0.8963 -0.8787 3625373 CBKinase1_014742 [O-][N+](=O)c1cc(ccc1NCCNS(=O)(=O)c2ccc(Br)cc2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F01 mock treatment 962509.0 6770.0 0.04 441144.0 -50000.0 -0.28 -0.1732 -0.6092 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F02 mock treatment 751100.0 -205000.0 -1.12 353986.0 -137000.0 -0.77 -1.3367 -0.9838 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F03 compound treatment 872826.0 -82900.0 -0.45 439045.0 -52100.0 -0.29 -0.5278 -0.9781 1723023 CBKinase1_014743 CCOC(=O)c1c(NC(=O)c2cccc(OC(=O)C)c2)scc1c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F04 compound treatment 962934.0 7190.0 0.04 433234.0 -57900.0 -0.33 -0.2031 -0.6176 3625374 CBKinase1_014744 O=C1CC(Cc2ccccc2)C(=O)N1CCCn3ccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F05 compound treatment 858697.0 -97000.0 -0.53 410712.0 -80400.0 -0.45 -0.6952 -0.997 3625375 CBKinase1_014745 CS(=O)(=O)N(CC(=O)Nc1cccc2ccccc12)c3ccc(I)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F06 compound treatment 1264639.0 309000.0 1.69 513258.0 22100.0 0.12 1.2806 0.7573 3625376 CBKinase1_014746 COCCNC(=O)Nc1ccc2nc(c3ccccn3)c(nc2c1)c4ccccn4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F07 compound treatment 916292.0 -39400.0 -0.22 481275.0 -9870.0 -0.06 -0.1916 -0.8615 3625377 CBKinase1_014747 COC(=O)CN(c1cccc(Cl)c1)S(=O)(=O)c2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F08 compound treatment 897071.0 -58700.0 -0.32 420868.0 -70300.0 -0.4 -0.5066 -0.9944 3625378 CBKinase1_014748 Oc1ccc(NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N3CCOCC3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F09 mock treatment 1102079.0 146000.0 0.8 512567.0 21400.0 0.12 0.6503 0.8048 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F10 mock treatment 882307.0 -73400.0 -0.4 591152.0 100000.0 0.56 0.1151 0.1664 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F11 compound treatment 942263.0 -13500.0 -0.07 600528.0 109000.0 0.62 0.3839 0.6183 1918152 CBKinase1_014749 CC(=O)c1ccc(NC(=O)CCCC(=O)O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F12 compound treatment 974749.0 19000.0 0.1 468718.0 -22400.0 -0.13 -0.016 -0.0979 3625379 CBKinase1_014750 CCOc1ccc(NS(=O)(=O)c2cc(ccc2OC)C(=O)O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F13 compound treatment 935287.0 -20500.0 -0.11 489910.0 -1240.0 -0.01 -0.0839 -0.7499 3625380 CBKinase1_014751 OCCCc1nnc(SCc2cccc(C#N)c2)n1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F14 compound treatment 821310.0 -134000.0 -0.73 537253.0 46100.0 0.26 -0.3352 -0.4306 3424756 CBKinase1_014752 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3cccc(c3)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F15 compound treatment 937961.0 -17800.0 -0.1 444114.0 -47000.0 -0.27 -0.2561 -0.9071 3625381 CBKinase1_014753 COC(=O)c1ccccc1NC(=O)c2c(NC(=O)CN3CCCCCC3)sc4CCCc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F16 compound treatment 923692.0 -32000.0 -0.17 428349.0 -62800.0 -0.35 -0.374 -0.9472 3625382 CBKinase1_014754 CC(N(c1ccc(Oc2ccccc2)cc1)S(=O)(=O)C)C(=O)Nc3cccc(C)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F17 mock treatment 803402.0 -152000.0 -0.83 478870.0 -12300.0 -0.07 -0.637 -0.7633 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F18 mock treatment 1009476.0 53700.0 0.29 542169.0 51000.0 0.29 0.4108 1.0 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F19 compound treatment 924207.0 -31500.0 -0.17 421087.0 -70100.0 -0.39 -0.401 -0.9308 3625383 CBKinase1_014755 OCCNCC(=O)Nc1sc2CCCc2c1C(=O)Nc3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F20 compound treatment 855671.0 -100000.0 -0.55 437316.0 -53800.0 -0.3 -0.6009 -0.9615 3625384 CBKinase1_014756 COc1ccc(cc1Cl)N(CC(=O)Nc2cccc(SC)c2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F21 compound treatment 669247.0 -286000.0 -1.56 451188.0 -40000.0 -0.23 -1.2653 -0.8007 1882538 CBKinase1_014757 Cc1ccc2ccc(C(Nc3ccccn3)c4c(F)cccc4Cl)c(O)c2n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F22 compound treatment 657465.0 -298000.0 -1.63 436955.0 -54200.0 -0.31 -1.3675 -0.8253 2085496 CBKinase1_014758 OC(=O)CN(c1ccccc1)S(=O)(=O)c2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F23 compound treatment 587703.0 -368000.0 -2.01 355327.0 -136000.0 -0.77 -1.9621 -0.9125 1443029 CBKinase1_014759 COc1cc(NS(=O)(=O)c2ccc(NC(=O)c3cccc4ccccc34)cc2)ncn1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 F24 compound treatment 684725.0 -271000.0 -1.48 402670.0 -88500.0 -0.5 -1.3989 -0.8959 3039657 CBKinase1_014760 NC(=O)CSc1nnc(c2cccnc2)n1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G01 compound treatment 1008483.0 52700.0 0.29 631489.0 140000.0 0.79 0.7629 0.9063 3625385 CBKinase1_014761 O=C(CCN1C(=O)c2ccccc2S1(=O)=O)Nc3cccc4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G02 compound treatment 322128.0 -634000.0 -3.46 177750.0 -313000.0 -1.77 -3.6951 -0.9513 1672720 CBKinase1_014762 COc1cccc(c1)C(=O)NC(c2ccc(C)cc2)c3cc(Cl)c4cccnc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G03 mock treatment 911891.0 -43900.0 -0.24 643609.0 152000.0 0.86 0.4384 0.4914 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G04 mock treatment 936421.0 -19300.0 -0.11 630059.0 139000.0 0.78 0.479 0.6064 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G05 compound treatment 925704.0 -30000.0 -0.16 631308.0 140000.0 0.79 0.4427 0.5486 3209506 CBKinase1_014763 O=C(CSc1nc(c(C#N)c(=O)[nH]1)c2ccccc2)N3CCCc4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G06 compound treatment 905580.0 -50200.0 -0.27 623329.0 132000.0 0.75 0.3332 0.4197 1313503 CBKinase1_014764 CNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3ccc(cc3)C(=O)N(C)C)c4ccccc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G07 compound treatment 931838.0 -23900.0 -0.13 635840.0 145000.0 0.82 0.4844 0.5865 3625386 CBKinase1_014765 COc1ccc(NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G08 compound treatment 932247.0 -23500.0 -0.13 679444.0 188000.0 1.06 0.6598 0.6172 1643749 CBKinase1_014766 COc1ccc(NC(=O)CCC(=O)c2ccc(cc2)c3ccccc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G09 compound treatment 908850.0 -46900.0 -0.26 615343.0 124000.0 0.7 0.314 0.4212 3625387 CBKinase1_014767 Cc1c(sc2ncn(CC(=O)Nc3cccc(Cl)c3C)c(=O)c12)C(=O)Nc4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G10 compound treatment 996284.0 40500.0 0.22 623980.0 133000.0 0.75 0.6859 0.8786 3625388 CBKinase1_014768 Cc1ccc(Cl)cc1NC(=O)CN(c2cccc(Cl)c2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G11 compound treatment 1077425.0 122000.0 0.66 686161.0 195000.0 1.1 1.247 0.9709 3625389 CBKinase1_014769 Clc1cc(NC(=O)CSc2nc3ccccc3s2)ccc1N4CCOCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G12 compound treatment 830792.0 -125000.0 -0.68 739704.0 249000.0 1.4 0.5083 0.3262 1099419 CBKinase1_014770 OC(=O)C(Cc1ccc(F)cc1)NC(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G13 compound treatment 1008090.0 52300.0 0.29 681667.0 191000.0 1.07 0.9614 0.8652 3625390 CBKinase1_014771 Cc1ccc(Cl)cc1NC(=O)CSc2nnc(c3ccc(cc3)[N+](=O)[O-])n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G14 compound treatment 853600.0 -102000.0 -0.56 689727.0 199000.0 1.12 0.3971 0.3176 3625391 CBKinase1_014772 CCn1c(SCC(=O)Nc2ccccc2C(F)(F)F)nnc1c3ccc(N)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G15 compound treatment 930280.0 -25500.0 -0.14 733722.0 243000.0 1.37 0.8685 0.632 2080554 CBKinase1_014773 CS(=O)(=O)N(CC(=O)O)Cc1ccccc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G16 compound treatment 965558.0 9820.0 0.05 714529.0 223000.0 1.26 0.9282 0.7365 3625392 CBKinase1_014774 CC(=O)Nc1ccc(cc1)c2nnc(SCC(=O)Nc3ccc(Cl)cc3Cl)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G17 compound treatment 903186.0 -52600.0 -0.29 725181.0 234000.0 1.32 0.7299 0.5407 3625393 CBKinase1_014775 CCC(Sc1ccccn1)C(=O)Nc2ccc(Br)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G18 compound treatment 929557.0 -26200.0 -0.14 681764.0 191000.0 1.07 0.6586 0.6077 3625394 CBKinase1_014776 O=C(CCN1C(=O)C2C(C3C=CC2C4CC43)C1=O)Oc5ccc6ccccc6c5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G19 mock treatment 857154.0 -98600.0 -0.54 673417.0 182000.0 1.03 0.3458 0.2982 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G20 mock treatment 850337.0 -105000.0 -0.58 685496.0 194000.0 1.1 0.3677 0.2971 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G21 compound treatment 849495.0 -106000.0 -0.58 661620.0 170000.0 0.96 0.2693 0.2399 3625395 CBKinase1_014777 COC(=O)c1ccccc1NC(=O)CN(C)S(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G22 compound treatment 781027.0 -175000.0 -0.95 625468.0 134000.0 0.76 -0.1391 -0.1143 3625396 CBKinase1_014778 COc1ccc(Cl)cc1NC(=O)CSc2nnc(o2)c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G23 compound treatment 655658.0 -300000.0 -1.64 593462.0 102000.0 0.58 -0.7507 -0.4322 1292911 CBKinase1_014779 Cc1nn(Cc2cccc(c2)C(=O)Nc3ccc(cc3)S(=O)(=O)N4CCCCC4)c(C)c1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 G24 compound treatment 818652.0 -137000.0 -0.75 659078.0 168000.0 0.95 0.1401 0.1161 1985760 CBKinase1_014780 Oc1nc(CSc2nnc(c3cccnc3)n2c4ccccc4)nc5ccccc15 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H01 compound treatment 960401.0 4660.0 0.03 599730.0 109000.0 0.61 0.4507 0.7359 1524650 CBKinase1_014781 OC1=C(C(N(CCN2CCOCC2)C1=O)c3ccc(Cl)cc3)C(=O)c4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H02 compound treatment 1120467.0 165000.0 0.9 676410.0 185000.0 1.04 1.3743 0.9972 1874009 CBKinase1_014782 Cc1c(oc2ccccc12)C(=O)Nc3sc4CCCCc4c3C(=O)NC5CCS(=O)(=O)C5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H03 mock treatment 988844.0 33100.0 0.18 591909.0 101000.0 0.57 0.5294 0.8882 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H04 mock treatment 951296.0 -4450.0 -0.02 607622.0 116000.0 0.66 0.447 0.6805 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H05 compound treatment 935810.0 -19900.0 -0.11 625132.0 134000.0 0.76 0.4571 0.599 3625397 CBKinase1_014783 COc1ccccc1n2nnnc2SCC(=O)Nc3ccccc3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H06 compound treatment 934449.0 -21300.0 -0.12 642928.0 152000.0 0.86 0.5227 0.6055 3625398 CBKinase1_014784 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccc(cc2)C(=O)N)C3CCCCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H07 compound treatment 933551.0 -22200.0 -0.12 618054.0 127000.0 0.72 0.4201 0.5791 1616716 CBKinase1_014785 Cc1ccccc1NC(=O)CCCC(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H08 compound treatment 1002871.0 47100.0 0.26 688420.0 197000.0 1.11 0.9682 0.8483 3625399 CBKinase1_014786 Cc1cccc(C)c1OCC(=O)Nc2cccc(c2)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H09 compound treatment 1026238.0 70500.0 0.38 594915.0 104000.0 0.58 0.6857 0.9794 3625400 CBKinase1_014787 CS(=O)(=O)N(CC(=O)Nc1ccc(F)cc1F)c2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H10 compound treatment 1024705.0 69000.0 0.38 654468.0 163000.0 0.92 0.9171 0.9222 3625401 CBKinase1_014788 CC(C)c1ccc(OCC(=O)Nc2cccc(C(=O)O)c2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H11 compound treatment 1037623.0 81900.0 0.45 665132.0 174000.0 0.98 1.0095 0.9367 1136830 CBKinase1_014789 CC(N(c1ccc(Oc2ccccc2)cc1)S(=O)(=O)C)C(=O)Nc3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H12 compound treatment 1043092.0 87400.0 0.48 693146.0 202000.0 1.14 1.1423 0.9254 3625402 CBKinase1_014790 [O-][N+](=O)c1cccc(OCC(=O)Nc2cccc(I)c2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H13 compound treatment 1001578.0 45800.0 0.25 654019.0 163000.0 0.92 0.8261 0.8682 3625403 CBKinase1_014791 Clc1ccccc1NC(=O)CSc2nnc(c3ccccc3Cl)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H14 compound treatment 1021921.0 66200.0 0.36 684426.0 193000.0 1.09 1.0258 0.8938 1304338 CBKinase1_014792 CCc1ccc(cc1)N(CC(=O)NC)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H15 compound treatment 1000960.0 45200.0 0.25 668381.0 177000.0 1.0 0.8809 0.8561 1870560 CBKinase1_014793 [O-][N+](=O)c1ccccc1C(=O)Nc2sc3CCCCc3c2C(=O)NCc4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H16 compound treatment 991432.0 35700.0 0.19 629292.0 138000.0 0.78 0.6884 0.8576 3625404 CBKinase1_014794 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)cc(Cl)c1)c2cccc(c2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H17 compound treatment 982994.0 27300.0 0.15 652501.0 161000.0 0.91 0.7483 0.812 3625405 CBKinase1_014795 [O-][N+](=O)c1ccccc1OCCCn2c(nc3ccccc3c2=O)c4ccc(Cl)cc4Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H18 compound treatment 1106580.0 151000.0 0.82 676876.0 186000.0 1.05 1.3225 0.9929 1134104 CBKinase1_014796 COc1ccc(cc1Cl)N(CC(=O)Nc2ccccc2OC)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H19 mock treatment 984059.0 28300.0 0.15 643745.0 153000.0 0.86 0.7175 0.821 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H20 mock treatment 999150.0 43400.0 0.24 623844.0 133000.0 0.75 0.6964 0.8877 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H21 compound treatment 934845.0 -20900.0 -0.11 598493.0 107000.0 0.61 0.3472 0.5638 3625406 CBKinase1_014797 COc1cc(cc(OC)c1OC)C(=O)Nc2sc3CCCCc3c2C(=O)NCc4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H22 compound treatment 944239.0 -11500.0 -0.06 622228.0 131000.0 0.74 0.478 0.6447 3625407 CBKinase1_014798 COc1ccc(cc1)N(Cc2cc3cc(C)ccc3nc2O)C(=O)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H23 compound treatment 992182.0 36400.0 0.2 643957.0 153000.0 0.86 0.7497 0.8481 3625408 CBKinase1_014799 O=C(CSc1nnc(c2cccc3ccccc23)n1c4ccccc4)NC5CC5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 H24 compound treatment 952637.0 -3100.0 -0.02 623287.0 132000.0 0.74 0.5147 0.6908 1848143 CBKinase1_014800 O=C(CSc1ccccn1)Nc2ccc(Oc3ccccc3)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I01 compound treatment 1112400.0 157000.0 0.86 334918.0 -156000.0 -0.88 -0.0179 -0.0146 3625409 CBKinase1_014801 Cc1cc(Cl)ccc1NC(=O)CSc2nnc(c3ccc(Br)cc3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I02 compound treatment 1085422.0 130000.0 0.71 455956.0 -35200.0 -0.2 0.3604 0.4901 1341016 CBKinase1_014802 COc1ccc(I)cc1S(=O)(=O)NCc2ccccn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I03 compound treatment 1029956.0 74200.0 0.41 467678.0 -23500.0 -0.13 0.193 0.4527 3625410 CBKinase1_014803 COc1ccc(cc1NC(=O)Cn2nc(C)c3ccccc3c2=O)c4nn(C)c(=O)c5ccccc45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I04 compound treatment 1023394.0 67700.0 0.37 471298.0 -19900.0 -0.11 0.1821 0.4717 3625411 CBKinase1_014804 COc1ccc(OC)c(c1)N(CC(=O)Nc2cccc(Cl)c2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I05 mock treatment 963787.0 8050.0 0.04 486350.0 -4800.0 -0.03 0.0119 0.2313 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I06 mock treatment 1100354.0 145000.0 0.79 508250.0 17100.0 0.1 0.6264 0.7876 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I07 compound treatment 1110137.0 154000.0 0.84 475315.0 -15800.0 -0.09 0.5329 0.6287 3625412 CBKinase1_014805 CC1=CCC(C(C1)C(=O)Nc2ccccc2NC(=O)c3ccc(cc3)C(F)(F)F)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I08 compound treatment 1095899.0 140000.0 0.77 497787.0 6640.0 0.04 0.5675 0.7408 3625413 CBKinase1_014806 CS(=O)(=O)N(CC(=O)Nc1cccnc1)c2cccc(Br)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I09 compound treatment 1132603.0 177000.0 0.97 505972.0 14800.0 0.08 0.7418 0.7654 3625414 CBKinase1_014807 NS(=O)(=O)c1ccc(NC(=S)NCc2cccnc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I10 compound treatment 1154826.0 199000.0 1.09 498019.0 6870.0 0.04 0.7959 0.7318 3625415 CBKinase1_014808 O=C(NCc1cccnc1)C2COc3ccccc3O2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I11 compound treatment 1156567.0 201000.0 1.1 633689.0 143000.0 0.8 1.3434 0.9883 3625416 CBKinase1_014809 COc1cc(NC(=O)C(C)Oc2ccc(Cl)cc2Cl)c(cc1OC)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I12 compound treatment 1173921.0 218000.0 1.19 498103.0 6950.0 0.04 0.87 0.73 1145895 CBKinase1_014810 COC(=O)c1ccccc1NC(=O)C(C)Oc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I13 compound treatment 1041055.0 85300.0 0.47 530416.0 39300.0 0.22 0.4859 0.9422 3625417 CBKinase1_014811 FC(F)(F)c1ccc(N2CCOCC2)c(NC(=O)COc3ccc(Cl)cc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I14 compound treatment 1116314.0 161000.0 0.88 484876.0 -6270.0 -0.04 0.5949 0.678 3625418 CBKinase1_014812 CCOc1ccc(NC(=O)C(C)Sc2nnnn2c3ccccc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I15 compound treatment 1071965.0 116000.0 0.63 478460.0 -12700.0 -0.07 0.3981 0.6235 3625419 CBKinase1_014813 COc1cc(NC(=O)c2ccc(Cn3cc(Cl)cn3)o2)c(cc1OC)C(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I16 compound treatment 1113443.0 158000.0 0.86 569272.0 78100.0 0.44 0.9202 0.9515 3625420 CBKinase1_014814 CCOC(=O)c1ccc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I17 compound treatment 1007350.0 51600.0 0.28 438442.0 -52700.0 -0.3 -0.0108 -0.0265 3625421 CBKinase1_014815 O=C(CSc1nc2sc3CCCCc3c2c(=O)[nH]1)N(c4ccccc4)c5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I18 compound treatment 1071865.0 116000.0 0.63 519204.0 28100.0 0.16 0.5601 0.8572 1407895 CBKinase1_014816 CC1=C(C(c2ccccn2)n3ncnc3N1)C(=O)Nc4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I19 compound treatment 1032311.0 76600.0 0.42 443392.0 -47800.0 -0.27 0.1053 0.2117 3625422 CBKinase1_014817 Fc1ccc(cc1)n2c(SCC(=O)Nc3ccc(Cl)c(Cl)c3)nnc2c4cccs4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I20 compound treatment 1063027.0 107000.0 0.59 580936.0 89800.0 0.51 0.772 0.9973 3625423 CBKinase1_014818 COC(=O)c1sc2ncn(CC(=O)Nc3cccc(Cl)c3C)c(=O)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I21 mock treatment 926613.0 -29100.0 -0.16 453641.0 -37500.0 -0.21 -0.2619 -0.9901 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I22 mock treatment 1069144.0 113000.0 0.62 449726.0 -41400.0 -0.23 0.2727 0.4121 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I23 compound treatment 1032095.0 76400.0 0.42 460294.0 -30900.0 -0.17 0.1718 0.3803 3625424 CBKinase1_014819 Cc1cccc(NC(=O)c2ccccc2NC(=O)COc3ccccc3)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 I24 compound treatment 997950.0 42200.0 0.23 379893.0 -111000.0 -0.63 -0.2805 -0.4198 3625425 CBKinase1_014820 Cc1ccc(NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J01 compound treatment 1047857.0 92100.0 0.5 514167.0 23000.0 0.13 0.4473 0.8613 3023735 CBKinase1_014821 COC(=O)c1c(C)nn(c1NC(=O)C(C)Oc2ccc(Cl)cc2)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J02 compound treatment 1090516.0 135000.0 0.74 446643.0 -44500.0 -0.25 0.3429 0.4411 3625426 CBKinase1_014822 O=C(Nc1cccc(CCc2ccccn2)c1)c3ccccc3Sc4ccccc4C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J03 compound treatment 953801.0 -1940.0 -0.01 728880.0 238000.0 1.34 0.94 0.7015 1686773 CBKinase1_014823 CCOC(=O)c1ccc(NC(=O)CSc2nc3sc4CCCCc4c3c(=O)[nH]2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J04 compound treatment 968097.0 12400.0 0.07 448467.0 -42700.0 -0.24 -0.1224 -0.4899 3625427 CBKinase1_014824 CN(CC(=O)Nc1ccc(C)c(C)c1)S(=O)(=O)c2ccc(Br)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J05 mock treatment 1062434.0 107000.0 0.58 497794.0 6650.0 0.04 0.4384 0.751 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J06 mock treatment 1085256.0 130000.0 0.71 556135.0 65000.0 0.37 0.759 0.9531 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J07 compound treatment 1107426.0 152000.0 0.83 465470.0 -25700.0 -0.14 0.4832 0.5748 3625428 CBKinase1_014825 CS(=O)(=O)N(CC(=O)Nc1ccc(F)cc1F)c2ccc(Br)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J08 compound treatment 1026211.0 70500.0 0.38 538188.0 47000.0 0.27 0.4595 0.9835 3625429 CBKinase1_014826 Cc1ccc(cc1NC(=O)c2cc(c(Cl)cc2Cl)S(=O)(=O)N3CCOCC3)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J09 compound treatment 1035481.0 79700.0 0.44 545737.0 54600.0 0.31 0.5254 0.9856 3625430 CBKinase1_014827 Oc1ccccc1C(=O)CC2(O)C(=O)N(Cc3ccccc3)c4ccc(Br)cc42 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J10 compound treatment 1084711.0 129000.0 0.7 622372.0 131000.0 0.74 1.0209 0.9997 3625431 CBKinase1_014828 Cc1ccccc1NC(=O)c2ccc(C)c(c2)S(=O)(=O)Nc3cc(ccc3C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J11 compound treatment 1134688.0 179000.0 0.98 567145.0 76000.0 0.43 0.9937 0.9315 1467705 CBKinase1_014829 Cc1ccc(NC(=O)CCC(=O)O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J12 compound treatment 1093216.0 137000.0 0.75 547420.0 56300.0 0.32 0.755 0.9266 3625432 CBKinase1_014830 Cc1ccc(cc1NC(=O)c2cccc(c2)S(=O)(=O)N3CCCC3)S(=O)(=O)N4CCOCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J13 compound treatment 1064509.0 109000.0 0.59 516607.0 25500.0 0.14 0.5214 0.8534 1485560 CBKinase1_014831 COc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(Cl)cc3Cl)cc2)ncn1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J14 compound treatment 1087228.0 131000.0 0.72 469196.0 -22000.0 -0.12 0.4201 0.5767 1213746 CBKinase1_014832 COc1cc(Cl)c(C)cc1NC(=O)C(CC(C)C)N2C(=O)c3ccccc3C2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J15 compound treatment 1061885.0 106000.0 0.58 431860.0 -59300.0 -0.33 0.1735 0.2593 3625433 CBKinase1_014833 Clc1ccc(cc1)n2c(SCC(=O)Nc3ccc(Cl)cc3Cl)nc4ccccc4c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J16 compound treatment 1033417.0 77700.0 0.42 500362.0 9210.0 0.05 0.3366 0.7878 3625434 CBKinase1_014834 Cc1c(NC(=O)CN(c2cc(Cl)ccc2Cl)S(=O)(=O)C)c(=O)n(c3ccccc3)n1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J17 compound treatment 1125088.0 169000.0 0.92 584597.0 93400.0 0.53 1.0262 0.9644 1874008 CBKinase1_014835 Cc1c(oc2ccccc12)C(=O)Nc3sc4CCCCc4c3C(=O)NCc5ccco5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J18 compound treatment 1063796.0 108000.0 0.59 603272.0 112000.0 0.63 0.864 0.9994 3625435 CBKinase1_014836 Cc1ccc(NC(=O)c2cc(NC(=O)C3CC=CCC3C(=O)O)ccc2N4CCOCC4)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J19 compound treatment 1055863.0 100000.0 0.55 503617.0 12500.0 0.07 0.4362 0.7915 3625436 CBKinase1_014837 COc1ccc(O)c(c1)C(c2c[nH]c3ccccc23)c4c[nH]c5ccccc45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J20 compound treatment 991109.0 35400.0 0.19 484602.0 -6550.0 -0.04 0.1104 0.5618 1725739 CBKinase1_014838 CCOc1ccc(NC(=O)CSc2ncccn2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J21 mock treatment 1019944.0 64200.0 0.35 432225.0 -58900.0 -0.33 0.013 0.0269 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J22 mock treatment 1060528.0 105000.0 0.57 442764.0 -48400.0 -0.27 0.2117 0.334 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J23 compound treatment 1114915.0 159000.0 0.87 577390.0 86200.0 0.49 0.9582 0.9623 3625437 CBKinase1_014839 Fc1ccc(cc1)C(=O)Nc2sc3CCCCc3c2C(=O)NCc4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 J24 compound treatment 1032737.0 77000.0 0.42 416400.0 -74700.0 -0.42 -7.0E-4 -0.0011 2072988 CBKinase1_014840 [O-][N+](=O)c1cc(ccc1NCCNS(=O)(=O)c2ccc3ccccc3c2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K01 compound treatment 981076.0 25300.0 0.14 445245.0 -45900.0 -0.26 -0.0851 -0.2902 3625438 CBKinase1_014841 COC(=O)CSc1nnc(C2COc3ccccc3O2)n1c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K02 compound treatment 971639.0 15900.0 0.09 454882.0 -36300.0 -0.2 -0.0832 -0.3745 1250099 CBKinase1_014842 Cc1c(NC(=O)CN(c2ccc(Cl)cc2C)S(=O)(=O)C)c(=O)n(c3ccccc3)n1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K03 compound treatment 960907.0 5170.0 0.03 428685.0 -62500.0 -0.35 -0.229 -0.6484 1624830 CBKinase1_014843 Cn1c(NC(=O)c2cccc(Cn3cc(Cl)cn3)c2)nc4ccccc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K04 compound treatment 902021.0 -53700.0 -0.29 446315.0 -44800.0 -0.25 -0.3861 -0.9972 1637495 CBKinase1_014844 OC(CN1c2ccccc2Sc3ccccc13)Cn4nnc5ccccc45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K05 compound treatment 1211114.0 255000.0 1.39 547507.0 56400.0 0.32 1.2105 0.8465 3625439 CBKinase1_014845 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)CSc4nnc[nH]4)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K06 compound treatment 332500.0 -623000.0 -3.4 195167.0 -296000.0 -1.67 -3.5856 -0.9462 1611779 CBKinase1_014846 COc1ccc(cc1)C(=O)NC(c2ccccc2Cl)c3cc(Cl)c4cccnc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K07 mock treatment 935448.0 -20300.0 -0.11 509010.0 17900.0 0.1 -0.0072 -0.0478 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K08 mock treatment 881272.0 -74500.0 -0.41 524012.0 32900.0 0.19 -0.1565 -0.3503 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K09 compound treatment 1052351.0 96600.0 0.53 476638.0 -14500.0 -0.08 0.3151 0.5904 3625440 CBKinase1_014847 CCc1ccc(NC(=O)CSc2nnc(c3ccc(Br)cc3)n2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K10 compound treatment 802372.0 -153000.0 -0.84 434602.0 -56500.0 -0.32 -0.8174 -0.9124 1191034 CBKinase1_014848 COc1cccc(c1)C(=O)NC(c2ccc(Cl)cc2)c3c(O)ccc4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K11 compound treatment 1012118.0 56400.0 0.31 539831.0 48700.0 0.27 0.4117 0.9984 1118385 CBKinase1_014849 Cc1c(Nc2ncnc3n(ncc23)c4ccccc4)c(=O)n(c5ccccc5)n1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K12 compound treatment 1015207.0 59500.0 0.32 465157.0 -26000.0 -0.15 0.126 0.3537 1399580 CBKinase1_014850 COc1ccc(cc1C(=O)O)S(=O)(=O)Nc2cccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K13 compound treatment 996063.0 40300.0 0.22 455819.0 -35300.0 -0.2 0.0149 0.05 1640992 CBKinase1_014851 COc1ccc(NC(=O)c2cccc(Cn3cc(Br)cn3)c2)cn1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K14 compound treatment 963666.0 7920.0 0.04 432465.0 -58700.0 -0.33 -0.2033 -0.6094 3625441 CBKinase1_014852 CCOC(=O)C1=C(C)Nc2ncnn2C1c3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K15 mock treatment 950111.0 -5630.0 -0.03 480495.0 -10700.0 -0.06 -0.0642 -0.9516 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K16 mock treatment 953173.0 -2570.0 -0.01 369192.0 -122000.0 -0.69 -0.496 -0.7214 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K17 compound treatment 975664.0 19900.0 0.11 445538.0 -45600.0 -0.26 -0.1049 -0.3757 3625442 CBKinase1_014853 CS(=O)(=O)N(CC(=O)Nc1ccc(I)cc1)Cc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K18 compound treatment 960146.0 4400.0 0.02 471917.0 -19200.0 -0.11 -0.0596 -0.5372 3625443 CBKinase1_014854 CCOc1ccccc1OCC(=O)Nc2sc3CC(C)CCc3c2C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K19 compound treatment 947177.0 -8560.0 -0.05 420836.0 -70300.0 -0.4 -0.3133 -0.7851 3625444 CBKinase1_014855 COc1cc(NC(=O)CSc2ccccc2)c(cc1OC)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K20 compound treatment 1486753.0 531000.0 2.9 796996.0 306000.0 1.72 3.2689 0.9692 3625445 CBKinase1_014856 N#Cc1nc(oc1NCCCN2CCOCC2)c3cccs3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K21 compound treatment 891984.0 -63800.0 -0.35 333597.0 -158000.0 -0.89 -0.8741 -0.9164 3625446 CBKinase1_014857 Cc1ccc(cc1)N(C2CS(=O)(=O)C=C2)C(=O)COc3ccc(cc3)C(C)(C)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K22 compound treatment 918643.0 -37100.0 -0.2 465831.0 -25300.0 -0.14 -0.2441 -0.9853 3625447 CBKinase1_014858 COc1ccc(CC(=O)Nc2cccc(c2)C(=O)Nc3ccccc3C(=O)O)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K23 mock treatment 837903.0 -118000.0 -0.64 295292.0 -196000.0 -1.1 -1.2355 -0.967 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 K24 mock treatment 1001925.0 46200.0 0.25 466849.0 -24300.0 -0.14 0.0814 0.2838 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L01 compound treatment 958621.0 2880.0 0.02 475588.0 -15600.0 -0.09 -0.0509 -0.5713 1576788 CBKinase1_014859 Clc1ccc(cc1)N2CC(CC2=O)C(=O)NCc3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L02 compound treatment 996262.0 40500.0 0.22 395815.0 -95300.0 -0.54 -0.2235 -0.3847 3625448 CBKinase1_014860 COc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(c3)C(F)(F)F)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L03 compound treatment 997464.0 41700.0 0.23 412123.0 -79000.0 -0.45 -0.1539 -0.3076 3625449 CBKinase1_014861 COc1cc(OC)cc(c1)c2nnc(SCC(=O)Nc3ccc(Cl)cc3)n2c4ccc(F)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L04 compound treatment 1027506.0 71800.0 0.39 435977.0 -55200.0 -0.31 0.0572 0.1143 1152992 CBKinase1_014862 COc1ccc(cc1OC)C(=O)CC2(O)C(=O)Nc3ccc(Cl)cc32 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L05 compound treatment 1037367.0 81600.0 0.45 419985.0 -71200.0 -0.4 0.0315 0.0525 3625450 CBKinase1_014863 Cc1cccc(N(CC(=O)Nc2cccc(c2)[N+](=O)[O-])S(=O)(=O)C)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L06 compound treatment 1091342.0 136000.0 0.74 453264.0 -37900.0 -0.21 0.3725 0.4834 1877358 CBKinase1_014864 CCOc1ccc2[nH]c(SCC(=O)Nc3ccc(Cl)cc3)nc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L07 mock treatment 981124.0 25400.0 0.14 438300.0 -52800.0 -0.3 -0.1126 -0.3429 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L08 mock treatment 1062728.0 107000.0 0.58 426927.0 -64200.0 -0.36 0.1571 0.2286 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L09 compound treatment 968415.0 12700.0 0.07 420746.0 -70400.0 -0.4 -0.2317 -0.5751 1264271 CBKinase1_014865 COc1cccc(c1)N(CC(=O)Nc2ccc(F)cc2F)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L10 compound treatment 884409.0 -71300.0 -0.39 408918.0 -82200.0 -0.46 -0.6031 -0.9963 3625451 CBKinase1_014866 CN(CC(=O)Nc1ccc(F)cc1)S(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L11 compound treatment 994405.0 38700.0 0.21 977792.0 487000.0 2.74 2.0888 0.7593 3625452 CBKinase1_014867 CCOC(=O)c1cnc2c(C)c(Cl)ccc2c1NCCCN3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L12 compound treatment 961152.0 5410.0 0.03 400836.0 -90300.0 -0.51 -0.3391 -0.665 3625453 CBKinase1_014868 CC1CCN(CC1)S(=O)(=O)c2ccc(Cl)c(c2)C(=O)Nc3ccccc3[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L13 compound treatment 899773.0 -56000.0 -0.31 390159.0 -101000.0 -0.57 -0.6186 -0.9575 3625454 CBKinase1_014869 Cc1ccc(C)c(c1)C(Nc2ccccn2)c3ccc4ccc(C)nc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L14 compound treatment 952250.0 -3490.0 -0.02 405766.0 -85400.0 -0.48 -0.3538 -0.7345 3625455 CBKinase1_014870 COc1ccc(cc1NC(=O)COc2ccc(cc2)C(C)(C)C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L15 mock treatment 926074.0 -29700.0 -0.16 413287.0 -77900.0 -0.44 -0.4249 -0.9082 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L16 mock treatment 960203.0 4460.0 0.02 389288.0 -102000.0 -0.57 -0.3887 -0.6765 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L17 compound treatment 1071451.0 116000.0 0.63 432182.0 -59000.0 -0.33 0.2117 0.2965 3625456 CBKinase1_014871 CCn1c(SCC(=O)c2ccc(Br)cc2)nnc1c3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L18 compound treatment 999992.0 44300.0 0.24 365677.0 -125000.0 -0.71 -0.3292 -0.4406 1522182 CBKinase1_014872 CS(=O)(=O)N(CC(=O)NC1CCCCCC1)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L19 compound treatment 892802.0 -62900.0 -0.34 469975.0 -21200.0 -0.12 -0.3274 -0.9 3625457 CBKinase1_014873 COc1ccc(cc1)c2nn(cc2C3NC(=O)NC(=C3C(=O)OCc4ccccc4)C)c5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L20 compound treatment 1071460.0 116000.0 0.63 428353.0 -62800.0 -0.35 0.1965 0.2713 3625458 CBKinase1_014874 CC(=O)c1cccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L21 compound treatment 970047.0 14300.0 0.08 372612.0 -119000.0 -0.67 -0.4172 -0.6202 3625459 CBKinase1_014875 Cn1c(SCC(=O)Nc2cccc(O)c2)nnc1c3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L22 compound treatment 1041162.0 85400.0 0.47 384924.0 -106000.0 -0.6 -0.0936 -0.1233 3625460 CBKinase1_014876 Oc1nc2ccccc2cc1CN(C(=O)c3ccc(cc3)[N+](=O)[O-])c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L23 mock treatment 995210.0 39500.0 0.22 400417.0 -90700.0 -0.51 -0.2092 -0.3771 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 L24 mock treatment 1079923.0 124000.0 0.68 378068.0 -113000.0 -0.64 0.0287 0.0309 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M01 compound treatment 993704.0 38000.0 0.21 531008.0 39900.0 0.22 0.3054 0.9992 3625461 CBKinase1_014877 CCOc1ccc(NC(=O)CSc2nc3sc(C)c(C)c3c(=O)n2c4ccc(C)cc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M02 compound treatment 955178.0 -563.0 0.0 489755.0 -1390.0 -0.01 -0.0077 -0.9162 3625462 CBKinase1_014878 COc1ccc2cc(ccc2c1)S(=O)(=O)NCCCN3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M03 compound treatment 1015751.0 60000.0 0.33 503905.0 12800.0 0.07 0.2825 0.8422 3625463 CBKinase1_014879 CCn1c(SCC(=O)Nc2cc(Cl)ccc2OC)nnc1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M04 compound treatment 962207.0 6470.0 0.04 573331.0 82200.0 0.46 0.3525 0.7588 1316116 CBKinase1_014880 Cc1cccc(OCC(=O)Nc2cccc(c2)c3nc4ccccc4s3)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M05 compound treatment 1006122.0 50400.0 0.28 608391.0 117000.0 0.66 0.6618 0.9245 3625464 CBKinase1_014881 CC(=O)Nc1cccc(c1)c2nnc(SCC(=O)Nc3ccccc3F)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M06 compound treatment 1038320.0 82600.0 0.45 499831.0 8680.0 0.05 0.3534 0.7793 1163026 CBKinase1_014882 Cc1cc(C)cc(OCC(=O)Nc2cccc(c2)c3nc4ccccc4o3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M07 compound treatment 1037582.0 81800.0 0.45 744906.0 254000.0 1.43 1.3273 0.8858 3625465 CBKinase1_014883 COc1cccc(NC(=O)CSc2nc(N)cc(N)n2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M08 compound treatment 881000.0 -74700.0 -0.41 515133.0 24000.0 0.14 -0.1929 -0.4489 3625466 CBKinase1_014884 CS(=O)(=O)N(CC(=O)Nc1ccccc1F)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M09 mock treatment 763073.0 -193000.0 -1.05 510163.0 19000.0 0.11 -0.668 -0.6318 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M10 mock treatment 953343.0 -2400.0 -0.01 760390.0 269000.0 1.52 1.0638 0.701 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M11 compound treatment 951558.0 -4180.0 -0.02 602231.0 111000.0 0.63 0.4266 0.6809 3625467 CBKinase1_014885 Cc1cccc(NC(=O)Cn2cnc3sc(cc3c2=O)c4ccccc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M12 compound treatment 908285.0 -47500.0 -0.26 541947.0 50800.0 0.29 0.0193 0.0499 3625468 CBKinase1_014886 CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)S(=O)(=O)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M13 mock treatment 961155.0 5410.0 0.03 606608.0 115000.0 0.65 0.4811 0.7385 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M14 mock treatment 941011.0 -14700.0 -0.08 580697.0 89500.0 0.5 0.3 0.587 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M15 compound treatment 935325.0 -20400.0 -0.11 618522.0 127000.0 0.72 0.4288 0.5903 3625469 CBKinase1_014887 CCOc1ccc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M16 compound treatment 1011877.0 56100.0 0.31 554133.0 63000.0 0.36 0.4677 0.9973 3625470 CBKinase1_014888 Clc1ccc(NC(=O)CSc2nnc(c3cccnc3)n2C4CCCCC4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M17 compound treatment 1007024.0 51300.0 0.28 479035.0 -12100.0 -0.07 0.1497 0.5194 3625471 CBKinase1_014889 COc1cc(OC)nc(NC(=O)CSc2nc3ccccc3[nH]2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M18 compound treatment 838205.0 -118000.0 -0.64 680534.0 189000.0 1.07 0.3011 0.2417 3625472 CBKinase1_014890 COc1ccc(cc1CSc2nnc(c3ccc(NC(=O)C)cc3)n2C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M19 compound treatment 980977.0 25200.0 0.14 502087.0 10900.0 0.06 0.141 0.9343 1587080 CBKinase1_014891 Clc1cc(Cl)c(cc1C(=O)NCC2CCCO2)S(=O)(=O)N3CCCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M20 compound treatment 1090187.0 134000.0 0.73 539275.0 48100.0 0.27 0.7108 0.9084 3625473 CBKinase1_014892 Nc1cc(=O)[nH]c(SCC(=O)Nc2ccccc2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M21 compound treatment 1065262.0 110000.0 0.6 570704.0 79600.0 0.45 0.7399 0.9899 3625474 CBKinase1_014893 [O-][N+](=O)c1ccc(NCCNS(=O)(=O)c2ccc(Br)cc2)c(c1)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M22 compound treatment 992751.0 37000.0 0.2 631711.0 141000.0 0.79 0.7031 0.8599 3625475 CBKinase1_014894 COc1ccc(NC(=O)c2ccco2)c(NC(=O)CSc3ccc(Cl)cc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M23 compound treatment 837632.0 -118000.0 -0.64 514620.0 23500.0 0.13 -0.3624 -0.5506 3625476 CBKinase1_014895 Brc1ccccc1NC(=O)CNS(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 M24 compound treatment 1013605.0 57900.0 0.32 580343.0 89200.0 0.5 0.5789 0.9749 3625477 CBKinase1_014896 O=C(CSc1nnc(c2cccnc2)n1c3ccccc3)Nc4ccc(Oc5ccccc5)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N01 compound treatment 970259.0 14500.0 0.08 554666.0 63500.0 0.36 0.3092 0.8432 3625478 CBKinase1_014897 CCn1c(SCC(=O)Nc2cccc(Cl)c2C)nnc1c3ccncc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N02 compound treatment 961875.0 6130.0 0.03 499946.0 8800.0 0.05 0.0587 0.9817 3625479 CBKinase1_014898 COc1cc(NC(=O)COc2ccc(Br)cc2C)c(OC)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N03 compound treatment 856355.0 -99400.0 -0.54 519733.0 28600.0 0.16 -0.2698 -0.4766 1174083 CBKinase1_014899 COc1ccccc1NC(=O)CN(c2ccccc2OC)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N04 compound treatment 987821.0 32100.0 0.18 418771.0 -72400.0 -0.41 -0.1646 -0.3708 3625480 CBKinase1_014900 COc1ccc(cc1[N+](=O)[O-])C(=O)CC2(O)C(=O)N(CC=C)c3ccccc32 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N05 compound treatment 932590.0 -23200.0 -0.13 488624.0 -2520.0 -0.01 -0.0994 -0.7818 3625481 CBKinase1_014901 CS(=O)(=O)N(CC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F)c2cccc(c2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N06 compound treatment 989967.0 34200.0 0.19 450416.0 -40700.0 -0.23 -0.0302 -0.1021 3625482 CBKinase1_014902 CN(CC(=O)Nc1ccccc1Cl)S(=O)(=O)c2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N07 compound treatment 1051828.0 96100.0 0.52 477819.0 -13300.0 -0.08 0.3178 0.5997 3625483 CBKinase1_014903 O=C(CSc1ncc2cc3ccccc3nc2c1C#N)Nc4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N08 compound treatment 996534.0 40800.0 0.22 467916.0 -23200.0 -0.13 0.0649 0.2511 3625484 CBKinase1_014904 Cc1ccccc1NC(=O)c2ccc(C)c(c2)S(=O)(=O)Nc3cccc(c3)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N09 mock treatment 1035404.0 79700.0 0.43 553151.0 62000.0 0.35 0.5546 0.9941 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N10 mock treatment 956373.0 632.0 0.0 454787.0 -36400.0 -0.2 -0.1425 -0.6951 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N11 compound treatment 1058783.0 103000.0 0.56 492429.0 1280.0 0.01 0.4029 0.7161 3625485 CBKinase1_014905 Cc1ccc(cc1)N(CC(=O)Nc2ccc(F)c(Cl)c2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N12 compound treatment 945725.0 -10000.0 -0.05 505189.0 14000.0 0.08 0.0173 0.1797 3625486 CBKinase1_014906 CN(CC(=O)Nc1ccc(cc1)[N+](=O)[O-])S(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N13 mock treatment 1009734.0 54000.0 0.29 504835.0 13700.0 0.08 0.263 0.8631 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N14 mock treatment 1005604.0 49900.0 0.27 472235.0 -18900.0 -0.11 0.1171 0.4006 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N15 compound treatment 322977.0 -633000.0 -3.45 192736.0 -298000.0 -1.68 -3.6321 -0.9453 3625487 CBKinase1_014907 Oc1c(ccc2cccnc12)C(Nc3ccccn3)c4cccc(Oc5ccccc5)c4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N16 compound treatment 969889.0 14100.0 0.08 495186.0 4040.0 0.02 0.0707 0.8781 1690140 CBKinase1_014908 CS(=O)(=O)N(CC(=O)Nc1cccc(F)c1)c2cccc3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N17 compound treatment 1031284.0 75500.0 0.41 452883.0 -38300.0 -0.22 0.1391 0.2989 3625488 CBKinase1_014909 Cc1ccc(NC(=O)COc2ccc(Br)cc2C)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N18 compound treatment 1033631.0 77900.0 0.43 441018.0 -50100.0 -0.28 0.1009 0.1976 1695447 CBKinase1_014910 CC(N(c1ccc(Oc2ccccc2)cc1)S(=O)(=O)C)C(=O)Nc3cccc(Cl)c3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N19 compound treatment 840772.0 -115000.0 -0.63 356529.0 -135000.0 -0.76 -0.9804 -0.9956 3625489 CBKinase1_014911 CC(C)c1ccc(cc1)C(Nc2ccccn2)c3ccc4ccc(C)nc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N20 compound treatment 1083941.0 128000.0 0.7 446180.0 -45000.0 -0.25 0.3157 0.4241 1326756 CBKinase1_014912 CC(C)c1cc(Br)c(C)cc1OCC(=O)Nc2ccccc2C(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N21 compound treatment 1065286.0 110000.0 0.6 546397.0 55200.0 0.31 0.6431 0.9537 3625490 CBKinase1_014913 COc1ccc(OC)c(NC(=O)c2c(NC(=O)CN3CCOCC3)sc4CCCc24)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N22 compound treatment 1064943.0 109000.0 0.6 493788.0 2640.0 0.01 0.4321 0.7245 1879755 CBKinase1_014914 OC(=O)C1C(C2OC1C=C2)C(=O)NCCc3cccc(Cl)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N23 compound treatment 981077.0 25300.0 0.14 445548.0 -45600.0 -0.26 -0.0839 -0.2876 3625491 CBKinase1_014915 COc1ccc(OC)c(NC(=O)COc2cc(C)c(Br)c(C)c2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 N24 compound treatment 1028216.0 72500.0 0.4 492077.0 928.0 0.01 0.2835 0.7164 1977552 CBKinase1_014916 O=C(CSc1nnc(c2ccncc2)n1c3ccccc3)c4c[nH]c5ccccc45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O01 compound treatment 933682.0 -22100.0 -0.12 497515.0 6370.0 0.04 -0.0598 -0.4758 3625492 CBKinase1_014917 CCn1c(SCC(=O)Nc2ccccc2C)nnc1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O02 compound treatment 922665.0 -33100.0 -0.18 440857.0 -50300.0 -0.28 -0.3281 -0.9763 1473899 CBKinase1_014918 COC(=O)c1ccc(NC(=O)CCC(=O)c2ccc(OC)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O03 compound treatment 958066.0 2320.0 0.01 515467.0 24300.0 0.14 0.1059 0.7693 3625493 CBKinase1_014919 COc1cc(OC)nc(NC(=O)CSc2nc3ccccc3o2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O04 compound treatment 949081.0 -6660.0 -0.04 421767.0 -69400.0 -0.39 -0.3022 -0.7695 3625494 CBKinase1_014920 Cc1cc(NC(=O)CN(c2ccc(Cl)c(c2)C(F)(F)F)S(=O)(=O)C)ccc1Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O05 compound treatment 958346.0 2600.0 0.01 436411.0 -54700.0 -0.31 -0.2081 -0.6738 3625495 CBKinase1_014921 Cn1c(SCC(=O)Nc2ccc(Cl)cc2Cl)nnc1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O06 compound treatment 975585.0 19800.0 0.11 428759.0 -62400.0 -0.35 -0.1721 -0.4676 3625496 CBKinase1_014922 CS(=O)(=O)N(CC(=O)NC1CC2CCC1C2)c3cc(Cl)cc(Cl)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O07 compound treatment 923766.0 -32000.0 -0.17 451173.0 -40000.0 -0.23 -0.2828 -0.992 3625497 CBKinase1_014923 COc1ccc(OC)c(NC(=O)CSc2nnc(C)s2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O08 compound treatment 941695.0 -14000.0 -0.08 443807.0 -47300.0 -0.27 -0.2429 -0.8749 1983080 CBKinase1_014924 COc1ccc(I)cc1S(=O)(=O)n2nnc3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O09 compound treatment 948100.0 -7640.0 -0.04 424331.0 -66800.0 -0.38 -0.2958 -0.7807 3625498 CBKinase1_014925 O=C(NCCCNC1=NS(=O)(=O)c2ccccc12)c3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O10 compound treatment 939743.0 -16000.0 -0.09 437573.0 -53600.0 -0.3 -0.2753 -0.8757 3625499 CBKinase1_014926 CCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nccc(/C=C/c3ccccc3Cl)n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O11 mock treatment 968401.0 12700.0 0.07 470763.0 -20400.0 -0.11 -0.0324 -0.2415 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O12 mock treatment 955404.0 -337.0 0.0 426028.0 -65100.0 -0.37 -0.2608 -0.7106 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O13 compound treatment 989566.0 33800.0 0.18 449995.0 -41200.0 -0.23 -0.0334 -0.1128 3625501 CBKinase1_014927 CS(=O)(=O)N(CC(=O)Nc1c(F)cccc1F)Cc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O14 compound treatment 966240.0 10500.0 0.06 458382.0 -32800.0 -0.18 -0.0901 -0.4657 3625502 CBKinase1_014928 Cc1[nH]c2ccccc2c1CCNS(=O)(=O)c3c(C)c(C)cc(C)c3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O15 compound treatment 975144.0 19400.0 0.11 458972.0 -32200.0 -0.18 -0.0533 -0.254 1532898 CBKinase1_014929 COC(Cc1nc2ccccc2s1)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O16 compound treatment 960595.0 4850.0 0.03 431616.0 -59500.0 -0.34 -0.2185 -0.6492 1344598 CBKinase1_014930 CCOC(=O)c1ccc(NC(=O)CSc2nc3sc4CCCCc4c3c(=O)n2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O17 compound treatment 933633.0 -22100.0 -0.12 431732.0 -59400.0 -0.33 -0.3222 -0.905 3625503 CBKinase1_014931 COC(=O)Cc1cc(O)n(n1)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O18 compound treatment 973862.0 18100.0 0.1 414768.0 -76400.0 -0.43 -0.2345 -0.5308 3625504 CBKinase1_014932 OC(=O)c1cc(NC(=O)C2CCCO2)cc(NC(=O)C3CCCO3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O19 compound treatment 1023431.0 67700.0 0.37 428207.0 -62900.0 -0.35 0.0105 0.0204 1134486 CBKinase1_014933 COc1ccc(NC(=O)CSc2nc3CCCC(=O)c3cc2C#N)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O20 compound treatment 1006747.0 51000.0 0.28 466327.0 -24800.0 -0.14 0.098 0.3144 3625505 CBKinase1_014934 COc1ccc(cc1)C(=O)Nc2ccccc2C(=O)NCC3CCCO3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O21 compound treatment 1021252.0 65500.0 0.36 424993.0 -66200.0 -0.37 -0.0108 -0.0208 3625506 CBKinase1_014935 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2c(C)cccc2C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O22 compound treatment 1017046.0 61300.0 0.33 369313.0 -122000.0 -0.69 -0.2489 -0.3258 3625507 CBKinase1_014936 COC(=O)CSc1nnc(c2sc3ccccc3c2Cl)n1c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O23 compound treatment 967169.0 11400.0 0.06 379563.0 -112000.0 -0.63 -0.4006 -0.6339 1249641 CBKinase1_014937 COc1ccc(cc1)N(CC(=O)Nc2ccccc2F)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 O24 compound treatment 998888.0 43100.0 0.24 410240.0 -80900.0 -0.46 -0.1559 -0.3037 3212374 CBKinase1_014938 CCc1ccccc1NC(=O)Cn2cnc3ccccc3c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P01 compound treatment 869718.0 -86000.0 -0.47 450591.0 -40600.0 -0.23 -0.4937 -0.9453 1247345 CBKinase1_014939 CC(C)C(=O)Nc1cccc(NC(=O)COc2ccccc2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P02 compound treatment 826244.0 -129000.0 -0.71 460858.0 -30300.0 -0.17 -0.6206 -0.8533 3625508 CBKinase1_014940 O=C(CCN1C(=O)C2C3CC(C=C3)C2C1=O)Nc4cccc5ccccc45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P03 compound treatment 867283.0 -88500.0 -0.48 452660.0 -38500.0 -0.22 -0.4949 -0.9348 3625509 CBKinase1_014941 COc1ccc(cc1NC(=O)C(CC(C)C)N2C(=O)c3ccccc3C2=O)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P04 compound treatment 907756.0 -48000.0 -0.26 504164.0 13000.0 0.07 -0.1334 -0.4902 3625510 CBKinase1_014942 Fc1ccc(NC(=O)CN(C2CCCCC2)S(=O)(=O)c3ccc(Cl)cc3)c(F)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P05 compound treatment 915860.0 -39900.0 -0.22 449705.0 -41400.0 -0.23 -0.3191 -0.9994 3625511 CBKinase1_014943 CCc1nnc(SCC(=O)Nc2ccc(C)cc2)[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P06 compound treatment 1069479.0 114000.0 0.62 533371.0 42200.0 0.24 0.6074 0.9133 3625512 CBKinase1_014944 OCCCNC(=O)Nc1ccc2nc(c3ccco3)c(nc2c1)c4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P07 compound treatment 914930.0 -40800.0 -0.22 452624.0 -38500.0 -0.22 -0.3111 -0.9999 1606265 CBKinase1_014945 Cc1c(Cl)cccc1NC(=O)CN(c2ccc(I)cc2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P08 compound treatment 896894.0 -58800.0 -0.32 451397.0 -39800.0 -0.22 -0.3856 -0.9845 3625513 CBKinase1_014946 CN(CC(=O)Nc1cccc(Cl)c1)S(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P09 compound treatment 914089.0 -41700.0 -0.23 474340.0 -16800.0 -0.09 -0.2278 -0.9247 3625514 CBKinase1_014947 COC(=O)CCN(C(=O)c1cccc(OC(=O)C)c1)c2ccccn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P10 compound treatment 907857.0 -47900.0 -0.26 426245.0 -64900.0 -0.37 -0.4435 -0.9864 3625515 CBKinase1_014948 CCCOc1ccc(cc1)C(=O)C2=C(O)C(=O)N(C2c3ccco3)c4nc(C)c(s4)C(=O)OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P11 mock treatment 936458.0 -19300.0 -0.11 470139.0 -21000.0 -0.12 -0.1582 -0.9983 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P12 mock treatment 1011339.0 55600.0 0.3 441041.0 -50100.0 -0.28 0.0149 0.036 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P13 compound treatment 981676.0 25900.0 0.14 498864.0 7720.0 0.04 0.1309 0.8835 3625516 CBKinase1_014949 COc1ccc(cc1NC(=S)NC(=O)COc2ccc(Br)cc2)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P14 compound treatment 898464.0 -57300.0 -0.31 458028.0 -33100.0 -0.19 -0.3531 -0.9696 1446926 CBKinase1_014950 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCC(C2)C(=O)Nc3ccc(cc3)N(C)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P15 compound treatment 852521.0 -103000.0 -0.56 514710.0 23600.0 0.13 -0.3046 -0.5261 3625517 CBKinase1_014951 Cc1cc(OCC(=O)Nc2ccccc2CO)cc(C)c1Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P16 compound treatment 891073.0 -64700.0 -0.35 393614.0 -97500.0 -0.55 -0.6384 -0.9771 3625518 CBKinase1_014952 COc1ccccc1NC(=O)CN(c2ccc(F)cc2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P17 compound treatment 936095.0 -19600.0 -0.11 399524.0 -91600.0 -0.52 -0.441 -0.8361 3625519 CBKinase1_014953 CCn1c(SCC(=O)N2c3ccccc3CCc4ccccc24)nnc1c5ccco5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P18 compound treatment 915912.0 -39800.0 -0.22 487992.0 -3160.0 -0.02 -0.1663 -0.7624 3625520 CBKinase1_014954 COC(=O)c1ccccc1NC(=O)CN(c2ccc(I)cc2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P19 compound treatment 1174885.0 219000.0 1.2 457952.0 -33200.0 -0.19 0.7137 0.5894 3625521 CBKinase1_014955 [O-][N+](=O)c1ccccc1NC(=O)CSc2nnnn2C3CCCCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P20 compound treatment 891574.0 -64200.0 -0.35 402898.0 -88300.0 -0.5 -0.5994 -0.9853 1615584 CBKinase1_014956 COc1ccccc1NC(=O)CN(c2ccccc2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P21 compound treatment 964813.0 9070.0 0.05 436408.0 -54700.0 -0.31 -0.1832 -0.5861 3625522 CBKinase1_014957 COc1ccc(cc1)C(=O)CSc2nnc(c3ccccc3Cl)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P22 compound treatment 1002612.0 46900.0 0.26 445310.0 -45800.0 -0.26 -0.0018 -0.0048 3625523 CBKinase1_014958 Clc1ccc(OCC(=O)NC(=S)Nc2ccccc2N3CCOCC3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P23 compound treatment 1223462.0 268000.0 1.46 628294.0 137000.0 0.77 1.5801 0.9557 3625524 CBKinase1_014959 COc1ccccc1C(=O)Nc2sc3CCCCc3c2C(=O)NCc4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2370 P24 compound treatment 1080074.0 124000.0 0.68 612421.0 121000.0 0.68 0.9633 1.0 3625525 CBKinase1_014960 COC(=O)c1ccccc1NC(=O)C(C)Oc2cccc(Cl)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A01 compound treatment 898470.0 -36200.0 -0.2 762564.0 31300.0 0.18 -0.0151 -0.057 3625526 CBKinase1_014961 CCn1c(SCC(=O)Nc2ccc(I)cc2C)nnc1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A02 compound treatment 927305.0 -7390.0 -0.04 619973.0 -111000.0 -0.63 -0.4721 -0.7511 3625527 CBKinase1_014962 CCc1cccc(OCC(=O)Nc2ccccc2C(=O)N)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A03 compound treatment 941655.0 6960.0 0.04 651717.0 -79500.0 -0.45 -0.2902 -0.6449 3625528 CBKinase1_014963 Cc1ccc(cc1)S(=O)(=O)NC2C(Sc3nnc(N)[nH]3)c4cccc5cccc2c45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A04 compound treatment 951978.0 17300.0 0.09 695132.0 -36100.0 -0.2 -0.0773 -0.3444 3625529 CBKinase1_014964 CCC(Sc1nnc(c2ccc(cc2)[N+](=O)[O-])n1C)C(=O)Nc3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A05 compound treatment 784472.0 -150000.0 -0.82 508895.0 -222000.0 -1.25 -1.4662 -0.9789 3625530 CBKinase1_014965 CC(C)c1ccc(OCC(=O)Nc2cc(ccc2C)c3nc4ccccc4[nH]3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A06 compound treatment 955045.0 20300.0 0.11 606157.0 -125000.0 -0.71 -0.4201 -0.5885 3625531 CBKinase1_014966 Cc1cccc(OCC(=O)Nc2cccc(c2)c3nnc(o3)c4ccccc4)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A07 compound treatment 847658.0 -87000.0 -0.48 686042.0 -45200.0 -0.25 -0.5163 -0.9574 3625532 CBKinase1_014967 NCCNc1ccc([N+](=O)[O-])c(Sc2nc3ccccc3[nH]2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A08 compound treatment 886902.0 -47800.0 -0.26 547589.0 -184000.0 -1.04 -0.9166 -0.8585 1419220 CBKinase1_014968 COc1ccc(OC)c(Nc2ncnc3n(ncc23)c4ccccc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A09 compound treatment 947450.0 12800.0 0.07 585692.0 -146000.0 -0.82 -0.531 -0.6448 3625533 CBKinase1_014969 COc1ccc(NC(=O)COc2ccccc2Cl)cc1NC(=O)c3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A10 compound treatment 1003814.0 69100.0 0.38 604492.0 -127000.0 -0.71 -0.2384 -0.2951 3625534 CBKinase1_014970 COC(=O)CSc1nnc(c2cc(OC)c(OC)c(OC)c2)n1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A11 compound treatment 775170.0 -160000.0 -0.87 715674.0 -15600.0 -0.09 -0.678 -0.7745 3625535 CBKinase1_014971 Cc1cc(ccc1F)S(=O)(=O)NCc2cccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A12 compound treatment 1021081.0 86400.0 0.47 467105.0 -264000.0 -1.49 -0.7193 -0.4606 3625536 CBKinase1_014972 CCOC(=O)C1=C(C)Nc2ncnn2C1c3ccccc3[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A13 mock treatment 1021904.0 87200.0 0.48 702865.0 -28400.0 -0.16 0.2235 0.4449 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A14 mock treatment 990263.0 55600.0 0.3 646225.0 -85000.0 -0.48 -0.1244 -0.2193 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A15 compound treatment 858679.0 -76000.0 -0.42 548202.0 -183000.0 -1.03 -1.0231 -0.9199 3625537 CBKinase1_014973 OC(=O)c1ccc(CSCCC#N)o1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A16 compound treatment 976632.0 41900.0 0.23 636209.0 -95100.0 -0.54 -0.217 -0.3724 3625538 CBKinase1_014974 CC(=O)Nc1ccc(NC(=O)CSC2=NC(CC(=O)N2)c3ccccc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A17 compound treatment 821016.0 -114000.0 -0.62 735781.0 4520.0 0.03 -0.4209 -0.6775 1708634 CBKinase1_014975 CCOC(=O)CC1N(CCNC1=O)C(=O)c2sc3ccccc3c2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A18 compound treatment 945890.0 11200.0 0.06 527735.0 -204000.0 -1.15 -0.768 -0.6685 3625539 CBKinase1_014976 CC(=O)c1ccccc1OC(=O)CCN2C(=O)c3ccccc3C2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A19 compound treatment 897012.0 -37700.0 -0.21 598208.0 -133000.0 -0.75 -0.6758 -0.869 3625540 CBKinase1_014977 COc1ccc(NC(=O)CCN2C(=O)c3ccccc3S2(=O)=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A20 compound treatment 936861.0 2160.0 0.01 581432.0 -150000.0 -0.84 -0.5888 -0.6972 3625541 CBKinase1_014978 COc1cc2nc(CCN3C(=O)c4ccccc4C3=O)oc(=O)c2cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A21 compound treatment 967797.0 33100.0 0.18 572966.0 -158000.0 -0.89 -0.5031 -0.5527 3625542 CBKinase1_014979 Cc1nnc(SCC(=O)Nc2c(C)cccc2C)[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A22 compound treatment 889417.0 -45300.0 -0.25 648616.0 -82600.0 -0.47 -0.5042 -0.9561 3625543 CBKinase1_014980 Cc1cccc(c1)n2c(N)cc(=O)nc2SCC(=O)N3c4ccccc4Sc5ccccc35 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A23 compound treatment 886899.0 -47800.0 -0.26 395930.0 -335000.0 -1.89 -1.521 -0.7972 3625544 CBKinase1_014981 Cc1nn(Cc2ccc(o2)C(=O)NC3CCCCC3)c(C)c1Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 A24 compound treatment 900006.0 -34700.0 -0.19 569334.0 -162000.0 -0.91 -0.7793 -0.836 3625545 CBKinase1_014982 CCn1c(SCC(=O)Nc2ccc(Cl)cc2C)nnc1c3ccncc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B01 compound treatment 957137.0 22400.0 0.12 567326.0 -164000.0 -0.92 -0.5668 -0.608 3625546 CBKinase1_014983 Clc1ccc(cc1Cl)C(=O)NCCCn2ccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B02 compound treatment 956965.0 22300.0 0.12 589413.0 -142000.0 -0.8 -0.4794 -0.5928 1731818 CBKinase1_014984 O=C(NCc1cccnc1)c2c(NC(=O)c3cccs3)sc4CCCCc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B03 compound treatment 935534.0 836.0 0.0 604404.0 -127000.0 -0.72 -0.5024 -0.7026 1538449 CBKinase1_014985 OCc1nc2ccccc2n1CCOc3cccc(Cl)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B04 compound treatment 951283.0 16600.0 0.09 654060.0 -77200.0 -0.44 -0.2437 -0.5482 3625547 CBKinase1_014986 C(CCSC1=NCCCN1)CSC2=NCCCN2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B05 compound treatment 917909.0 -16800.0 -0.09 703653.0 -27600.0 -0.16 -0.1749 -0.9681 3625548 CBKinase1_014987 Cc1ccc(NC(=O)C2C(C3OC2C=C3)C(=O)O)cc1[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B06 compound treatment 974905.0 40200.0 0.22 647233.0 -84000.0 -0.47 -0.1797 -0.3442 1518267 CBKinase1_014988 CCOC(=O)c1ccc(NC(=O)CSc2nc3sc4CCCc4c3c(=O)[nH]2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B07 compound treatment 859387.0 -75300.0 -0.41 608687.0 -123000.0 -0.69 -0.7793 -0.9693 3025261 CBKinase1_014989 Cc1ccc(C)c(NC(CC(=O)c2ccccc2)C(=O)O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B08 compound treatment 988892.0 54200.0 0.3 650377.0 -80900.0 -0.46 -0.1132 -0.2082 1445100 CBKinase1_014990 CCc1ccccc1OCC(=O)Nc2sc3CCCCc3c2C(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B09 compound treatment 517930.0 -417000.0 -2.28 248722.0 -483000.0 -2.72 -3.5321 -0.9961 3625549 CBKinase1_014991 Cc1ccc2ccc(C(Nc3ccccn3)c4ccc(Cl)c(Cl)c4)c(O)c2n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B10 compound treatment 930719.0 -3980.0 -0.02 646026.0 -85200.0 -0.48 -0.3551 -0.7383 3625550 CBKinase1_014992 Cc1ccc(cc1)c2nnc(SCC(=O)Nc3ccccc3F)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B11 compound treatment 853123.0 -81600.0 -0.45 683532.0 -47700.0 -0.27 -0.5052 -0.9709 3625551 CBKinase1_014993 CN1C(=O)C(O)(CC(=O)c2ccccn2)c3cc(Br)ccc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B12 compound treatment 991186.0 56500.0 0.31 835124.0 104000.0 0.59 0.632 0.9552 3625552 CBKinase1_014994 [O-][N+](=O)c1ccc(cc1)C(=O)NCCNS(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B13 mock treatment 998879.0 64200.0 0.35 705016.0 -26200.0 -0.15 0.1432 0.3764 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B14 mock treatment 892769.0 -41900.0 -0.23 670845.0 -60400.0 -0.34 -0.4027 -0.9813 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B15 compound treatment 895266.0 -39400.0 -0.22 560003.0 -171000.0 -0.97 -0.8348 -0.8441 3625553 CBKinase1_014995 COc1ccc(OC)c(NC(=O)COc2cc(C)cc(C)c2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B16 compound treatment 986071.0 51400.0 0.28 590796.0 -140000.0 -0.79 -0.3615 -0.4304 3625554 CBKinase1_014996 Cc1cc2ccccc2n3c(SCC(=O)NCc4ccco4)nnc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B17 compound treatment 993933.0 59200.0 0.32 677612.0 -53700.0 -0.3 0.0148 0.0335 3625555 CBKinase1_014997 COC(=O)c1cc(OC)c(OC)cc1NC(=O)COc2cccc(C)c2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B18 compound treatment 1016993.0 82300.0 0.45 625768.0 -105000.0 -0.59 -0.1028 -0.1379 1130123 CBKinase1_014998 Cc1ccc2nc(O)c(CCC(=O)O)c(C)c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B19 compound treatment 859911.0 -74800.0 -0.41 679741.0 -51500.0 -0.29 -0.4941 -0.9861 3625556 CBKinase1_014999 Cc1cc(C)c(C)c(OCC(=O)Nc2ccccc2C(=O)N)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B20 compound treatment 711005.0 -224000.0 -1.22 554564.0 -177000.0 -1.0 -1.5678 -0.9949 3625557 CBKinase1_015000 CC(C)c1nnc(s1)N2C(C(=C(O)C2=O)C(=O)c3cccs3)c4cccnc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B21 compound treatment 881571.0 -53100.0 -0.29 687001.0 -44300.0 -0.25 -0.3815 -0.9972 1875024 CBKinase1_015001 [O-][N+](=O)c1ccc(cc1)C(=O)Nc2sc3CCCCc3c2C(=O)NCc4cccnc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B22 compound treatment 906310.0 -28400.0 -0.15 652254.0 -79000.0 -0.45 -0.4245 -0.9002 3625558 CBKinase1_015002 Cc1ccc(Oc2ccc(NC(=O)CCCC(=O)O)cc2)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B23 compound treatment 843675.0 -91000.0 -0.5 689266.0 -42000.0 -0.24 -0.5188 -0.9425 3625559 CBKinase1_015003 COc1cc2c(cc1NC(=O)COc3cccc(C)c3C)oc4ccccc42 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 B24 compound treatment 918514.0 -16200.0 -0.09 637875.0 -93400.0 -0.53 -0.4347 -0.8144 3625560 CBKinase1_015004 CCc1ccccc1NC(=O)c2ccccc2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C01 compound treatment 970512.0 35800.0 0.2 795119.0 63900.0 0.36 0.3928 0.9589 3625561 CBKinase1_015005 COc1ccc(cc1)C(=O)Nc2ccccc2C(=O)N3CCN(CCO)CC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C02 compound treatment 901417.0 -33300.0 -0.18 763483.0 32200.0 0.18 -1.0E-4 -3.0E-4 3625562 CBKinase1_015006 [O-][N+](=O)c1cc(ccc1NCCNC(=O)c2ccc(F)cc2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C03 compound treatment 1000054.0 65400.0 0.36 676899.0 -54400.0 -0.31 0.0356 0.0758 3625563 CBKinase1_015007 COc1ccc(cc1S(=O)(=O)NCc2ccccc2)c3nnnn3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C04 compound treatment 953574.0 18900.0 0.1 599621.0 -132000.0 -0.74 -0.4518 -0.6031 3625564 CBKinase1_015008 O=C(NCc1ccco1)c2ccc3C(=O)N(CC4CCCO4)C(=O)c3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C05 compound treatment 922692.0 -12000.0 -0.07 634511.0 -96800.0 -0.55 -0.432 -0.7864 3625565 CBKinase1_015009 Ic1ccccc1C(=O)NCCCn2ccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C06 compound treatment 930948.0 -3750.0 -0.02 692319.0 -38900.0 -0.22 -0.1697 -0.7697 3625566 CBKinase1_015010 CN(CC(=O)Nc1ccc2OCCOc2c1)S(=O)(=O)c3cc(Cl)ccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C07 compound treatment 952639.0 17900.0 0.1 659714.0 -71600.0 -0.4 -0.2159 -0.5202 3625567 CBKinase1_015011 [O-][N+](=O)c1ccc(cc1)c2nnc(SCc3ccccc3C#N)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C08 compound treatment 919572.0 -15100.0 -0.08 673701.0 -57600.0 -0.32 -0.2878 -0.8597 3625568 CBKinase1_015012 Cn1c(SCC(=O)c2ccc(cc2)[N+](=O)[O-])nnc1c3sc4ccccc4c3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C09 compound treatment 944187.0 9490.0 0.05 669129.0 -62100.0 -0.35 -0.211 -0.596 3625569 CBKinase1_015013 COc1cc(NC(=S)NCc2ccc(cc2)S(=O)(=O)N)c(OC)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C10 compound treatment 1016942.0 82200.0 0.45 731165.0 -99.6 0.0 0.3171 0.7062 3625570 CBKinase1_015014 CN(C)CCCNc1oc(nc1C#N)c2ccccc2F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C11 mock treatment 947781.0 13100.0 0.07 579490.0 -152000.0 -0.86 -0.5544 -0.6458 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C12 mock treatment 965506.0 30800.0 0.17 801540.0 70300.0 0.4 0.399 0.9272 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C13 compound treatment 970348.0 35700.0 0.19 743864.0 12600.0 0.07 0.1878 0.9066 3625571 CBKinase1_015015 COc1ccc(C)cc1NC(=O)CSc2nnc(o2)c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C14 compound treatment 876493.0 -58200.0 -0.32 558482.0 -173000.0 -0.97 -0.9133 -0.8916 3625572 CBKinase1_015016 CCc1ccccc1NC(=O)CSc2nnc(c3ccccc3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C15 mock treatment 934551.0 -147.0 0.0 655872.0 -75400.0 -0.42 -0.301 -0.7084 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C16 mock treatment 951450.0 16800.0 0.09 753382.0 22100.0 0.12 0.1528 0.9884 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C17 compound treatment 902608.0 -32100.0 -0.18 771113.0 39800.0 0.22 0.0349 0.1226 3625573 CBKinase1_015017 [O-][N+](=O)c1ccc(cc1)C(=O)CCNc2ccc3c(c2)oc4ccccc43 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C18 compound treatment 919540.0 -15200.0 -0.08 562017.0 -169000.0 -0.95 -0.7331 -0.7656 3625574 CBKinase1_015018 CCOC(=O)c1cnc2ccc(F)cc2c1NCc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C19 compound treatment 775771.0 -159000.0 -0.87 624221.0 -107000.0 -0.6 -1.0402 -0.9842 3625575 CBKinase1_015019 Clc1ccc(NC(=O)c2ccco2)c(c1)C(=O)NCc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C20 compound treatment 921580.0 -13100.0 -0.07 641925.0 -89300.0 -0.5 -0.4067 -0.7996 3625576 CBKinase1_015020 Clc1ccc(NC(=O)CSc2ccccn2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C21 compound treatment 1197843.0 263000.0 1.44 760490.0 29200.0 0.16 1.1323 0.7831 3025337 CBKinase1_015021 Cc1ccc(cc1)S(=O)(=O)CC(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C22 compound treatment 808722.0 -126000.0 -0.69 662336.0 -68900.0 -0.39 -0.761 -0.9635 3117755 CBKinase1_015022 Cc1ccc(cc1)S(=O)(=O)NC2C(Sc3ccccn3)c4cccc5cccc2c45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C23 compound treatment 953235.0 18500.0 0.1 821210.0 89900.0 0.51 0.43 0.8318 3625577 CBKinase1_015023 Cc1nn(Cc2cccc(c2)C(=O)Nc3ccc4oc(=O)cc(c4c3)C(F)(F)F)c(C)c1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 C24 compound treatment 879881.0 -54800.0 -0.3 578829.0 -152000.0 -0.86 -0.8192 -0.9004 3625578 CBKinase1_015024 CC1CCc2c(C1)sc3ncnc(SCC(=O)NC4CCCCC4)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D01 compound treatment 852898.0 -81800.0 -0.45 718041.0 -13200.0 -0.07 -0.3685 -0.8139 3625579 CBKinase1_015025 COc1ccc(cc1)N2CCN(CC2)c3nc(NCCO)nc(n3)N4CCOCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D02 compound treatment 900702.0 -34000.0 -0.19 539389.0 -192000.0 -1.08 -0.896 -0.8165 3625580 CBKinase1_015026 CCn1c2ccccc2c3cc(NC(=O)Cc4ccccc4[N+](=O)[O-])ccc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D03 compound treatment 935383.0 685.0 0.0 494925.0 -236000.0 -1.33 -0.9393 -0.7051 3625581 CBKinase1_015027 NC(=O)c1c(NC(=O)COc2ccc3ccccc3c2)sc4CCCCCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D04 compound treatment 889356.0 -45300.0 -0.25 620754.0 -111000.0 -0.62 -0.6155 -0.9183 3625582 CBKinase1_015028 Cn1c(SCC(=O)c2ccc(Cl)cc2)nnc1c3ccncc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D05 compound treatment 946141.0 11400.0 0.06 681857.0 -49400.0 -0.28 -0.1527 -0.5352 3625583 CBKinase1_015029 [O-][N+](=O)c1ccccc1OCC(=O)Nc2ccccc2N3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D06 compound treatment 938655.0 3960.0 0.02 674730.0 -56500.0 -0.32 -0.21 -0.6577 1425208 CBKinase1_015030 CN(CC(=O)O)S(=O)(=O)c1ccc(Br)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D07 compound treatment 921812.0 -12900.0 -0.07 729008.0 -2260.0 -0.01 -0.0587 -0.8216 3625584 CBKinase1_015031 COc1cc(cc(OC)c1OC)C2N(Cc3ccco3)C(=O)C(=C2C(=O)c4cccs4)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D08 compound treatment 949008.0 14300.0 0.08 562759.0 -169000.0 -0.95 -0.6163 -0.6468 3625585 CBKinase1_015032 CCn1c(SCC(=O)Nc2ccc(Cl)c(Cl)c2)nnc1c3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D09 compound treatment 928693.0 -6000.0 -0.03 557789.0 -173000.0 -0.98 -0.7146 -0.7304 1697366 CBKinase1_015033 OC1=C(C(N(Cc2ccco2)C1=O)c3ccccc3)C(=O)c4cccs4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D10 compound treatment 948738.0 14000.0 0.08 489033.0 -242000.0 -1.37 -0.9112 -0.6664 3625586 CBKinase1_015034 CN(CC(=O)Nc1ccc(C)cc1C)S(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D11 mock treatment 936333.0 1640.0 0.01 567690.0 -164000.0 -0.92 -0.6456 -0.7002 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D12 mock treatment 1012742.0 78000.0 0.43 579243.0 -152000.0 -0.86 -0.3046 -0.3183 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D13 compound treatment 1009198.0 74500.0 0.41 586592.0 -145000.0 -0.82 -0.289 -0.3171 1875027 CBKinase1_015035 Clc1ccc(cc1)C(=O)Nc2sc3CCCCc3c2C(=O)NCc4cccnc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D14 compound treatment 837187.0 -97500.0 -0.53 557143.0 -174000.0 -0.98 -1.0704 -0.9587 3625587 CBKinase1_015036 Cc1nc([N+](=O)[O-])c(Sc2nc3cc(C)c(C)cc3[nH]2)n1Cc4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D15 mock treatment 995820.0 61100.0 0.33 742076.0 10800.0 0.06 0.279 0.8226 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D16 mock treatment 915085.0 -19600.0 -0.11 671370.0 -59900.0 -0.34 -0.3144 -0.8878 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D17 compound treatment 957800.0 23100.0 0.13 614880.0 -116000.0 -0.66 -0.3747 -0.5609 3625588 CBKinase1_015037 COc1ccc(NC(=O)COc2cc(C)cc(C)c2C)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D18 compound treatment 897491.0 -37200.0 -0.2 633942.0 -97300.0 -0.55 -0.5315 -0.9087 3625589 CBKinase1_015038 CCNc1nc(SCCOc2ccccc2)nc(n1)N(C)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D19 compound treatment 873550.0 -61100.0 -0.33 664766.0 -66500.0 -0.37 -0.5011 -0.9983 3625590 CBKinase1_015039 CCNC(=O)c1c(NC(=O)C(C)Oc2ccccc2F)sc3CCCCc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D20 compound treatment 830636.0 -104000.0 -0.57 672051.0 -59200.0 -0.33 -0.6377 -0.9679 3625591 CBKinase1_015040 Cc1nc(CSc2nc3sc4CCCCc4c3c(=O)n2CC=C)cs1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D21 compound treatment 881983.0 -52700.0 -0.29 673208.0 -58100.0 -0.33 -0.4349 -0.998 3625592 CBKinase1_015041 COc1cccc(OCCCCSc2ncccn2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D22 compound treatment 832444.0 -102000.0 -0.56 788661.0 57400.0 0.32 -0.166 -0.2573 3625593 CBKinase1_015042 [O-][N+](=O)c1cccc(COC(=O)c2ccccc2NC(=O)c3ccccc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D23 compound treatment 802921.0 -132000.0 -0.72 655156.0 -76100.0 -0.43 -0.8121 -0.9695 3625594 CBKinase1_015043 COC(=O)c1ccccc1NC(=O)C(C)(C)Oc2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 D24 compound treatment 886902.0 -47800.0 -0.26 706397.0 -24900.0 -0.14 -0.2836 -0.9575 3625595 CBKinase1_015044 CC(=O)Nc1ccccc1C(=O)OCc2cccc(c2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E01 mock treatment 780279.0 -154000.0 -0.84 610814.0 -120000.0 -0.68 -1.0762 -0.9942 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E02 mock treatment 835566.0 -99100.0 -0.54 715313.0 -16000.0 -0.09 -0.4463 -0.8134 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E03 compound treatment 900319.0 -34400.0 -0.19 695378.0 -35900.0 -0.2 -0.2757 -0.9993 3625596 CBKinase1_015045 COc1ccc(OC)c(c1)S(=O)(=O)Nc2cc(OC)c(Cl)cc2OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E04 compound treatment 829663.0 -105000.0 -0.57 762949.0 31700.0 0.18 -0.2792 -0.4649 3625597 CBKinase1_015046 Fc1ccc(NC(=O)CSc2nc(cc(=O)[nH]2)C(F)(F)F)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E05 compound treatment 779288.0 -155000.0 -0.85 729180.0 -2080.0 -0.01 -0.6083 -0.7168 3625598 CBKinase1_015047 COC(=O)c1ccc(NC(=O)CSc2nnc(c3ccc(NC(=O)C)cc3)n2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E06 compound treatment 807516.0 -127000.0 -0.69 657875.0 -73400.0 -0.41 -0.7835 -0.9694 3625599 CBKinase1_015048 [O-][N+](=O)c1ccc(cc1)c2nnc(SCC(=O)Nc3ccc(F)cc3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E07 compound treatment 332913.0 -602000.0 -3.29 229694.0 -502000.0 -2.83 -4.3222 -0.9972 1361932 CBKinase1_015049 Cc1ccc2n(CC(O)CN3CCN(CCO)CC3)c(c(c4ccccc4)c2c1)c5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E08 compound treatment 999450.0 64800.0 0.35 713387.0 -17900.0 -0.1 0.1787 0.4862 3625600 CBKinase1_015050 Cc1cccc(c1)n2c(N)cc(=O)nc2SCC(=O)Nc3sc4CCCCCCc4c3C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E09 mock treatment 854528.0 -80200.0 -0.44 675778.0 -55500.0 -0.31 -0.5306 -0.9864 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E10 mock treatment 834752.0 -99900.0 -0.55 699689.0 -31600.0 -0.18 -0.5117 -0.8915 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E11 compound treatment 778943.0 -156000.0 -0.85 734717.0 3450.0 0.02 -0.5875 -0.6907 3625601 CBKinase1_015051 CCOc1ccccc1OCC(=O)Nc2ccccc2C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E12 compound treatment 297167.0 -638000.0 -3.48 201256.0 -530000.0 -2.99 -4.5735 -0.9971 1307243 CBKinase1_015052 OC(CNC1CCCC1)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E13 compound treatment 809699.0 -125000.0 -0.68 725783.0 -5480.0 -0.03 -0.5044 -0.7384 3625602 CBKinase1_015053 CCC(Sc1nnc(c2ccc(NC(=O)C)cc2)n1C)C(=O)Nc3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E14 compound treatment 1008266.0 73600.0 0.4 796032.0 64800.0 0.37 0.5421 0.9989 3625603 CBKinase1_015054 COc1cccc(NC(=O)CSc2nc(C)c(C)c(C)c2C#N)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E15 compound treatment 885133.0 -49600.0 -0.27 674911.0 -56400.0 -0.32 -0.4159 -0.9968 3625604 CBKinase1_015055 CCOC(=O)CN(C)C1=NS(=O)(=O)c2ccccc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E16 compound treatment 822018.0 -113000.0 -0.62 784727.0 53500.0 0.3 -0.2219 -0.324 3625605 CBKinase1_015056 CC1CCc2c(C(=O)N)c(NC(=O)c3ccc(Cn4cc(Br)cn4)o3)sc2C1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E17 mock treatment 822007.0 -113000.0 -0.62 732474.0 1210.0 0.01 -0.4302 -0.6992 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E18 mock treatment 849388.0 -85300.0 -0.47 887582.0 156000.0 0.88 0.2937 0.2947 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E19 compound treatment 686234.0 -248000.0 -1.36 634180.0 -97100.0 -0.55 -1.3461 -0.9203 3625606 CBKinase1_015057 [O-][N+](=O)c1ccc(cc1NCc2cccnc2)N3CCN(CC3)C(=O)c4ccccc4Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E20 compound treatment 700201.0 -234000.0 -1.28 692720.0 -38500.0 -0.22 -1.0589 -0.8154 3625607 CBKinase1_015058 Cc1cccc(OCC(=O)Nc2cc(ccc2N3CCOCC3)C(F)(F)F)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E21 compound treatment 814321.0 -120000.0 -0.66 720826.0 -10400.0 -0.06 -0.5063 -0.7673 1348243 CBKinase1_015059 Fc1ccccc1c2nc(C#N)c(NCCN3CCOCC3)o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E22 compound treatment 551456.0 -383000.0 -2.09 684199.0 -47100.0 -0.27 -1.6671 -0.7904 3625608 CBKinase1_015060 O=C(CCN1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)Oc6cccc7cccnc67 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E23 compound treatment 609522.0 -325000.0 -1.78 652988.0 -78300.0 -0.44 -1.5673 -0.8568 3625609 CBKinase1_015061 Cc1ccc(NC(=O)CSc2nc3ccccc3s2)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 E24 compound treatment 444299.0 -490000.0 -2.68 473954.0 -257000.0 -1.45 -2.9187 -0.9585 3625610 CBKinase1_015062 O=C(CSc1nnc(c2ccccc2)n1C3CCCCC3)Nc4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F01 mock treatment 626985.0 -308000.0 -1.68 643441.0 -87800.0 -0.5 -1.5379 -0.8781 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F02 mock treatment 810064.0 -125000.0 -0.68 503184.0 -228000.0 -1.29 -1.3902 -0.9558 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F03 compound treatment 798721.0 -136000.0 -0.74 518491.0 -213000.0 -1.2 -1.373 -0.9734 3625611 CBKinase1_015063 FC(F)(F)c1ccc(Cl)c(NC(=O)CCCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F04 compound treatment 754225.0 -180000.0 -0.99 676076.0 -55200.0 -0.31 -0.9167 -0.8872 3625612 CBKinase1_015064 COc1ccc(cc1)n2c(SCC(=O)c3ccccc3)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F05 compound treatment 871605.0 -63100.0 -0.34 645648.0 -85600.0 -0.48 -0.5848 -0.9863 3625613 CBKinase1_015065 [O-][N+](=O)c1ccccc1OC(=O)CCCOc2ccc(Cl)cc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F06 compound treatment 800112.0 -135000.0 -0.73 719850.0 -11400.0 -0.06 -0.5651 -0.7661 1983963 CBKinase1_015066 CC(CC(=O)O)CC(=O)Nc1ccc(cc1)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F07 compound treatment 893339.0 -41400.0 -0.23 883298.0 152000.0 0.86 0.4463 0.5036 3625614 CBKinase1_015067 COC(=O)c1ccc(cc1)C2N(Cc3ccco3)C(=O)C(=C2C(=O)c4ccco4)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F08 compound treatment 2202480.0 1270000.0 6.92 1272800.0 542000.0 3.05 7.0525 0.9323 3625615 CBKinase1_015068 COc1cc(NC(=O)c2ccccc2)c(OC)cc1NC(=O)COc3ccc(Cl)cc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F09 mock treatment 927721.0 -6980.0 -0.04 651894.0 -79400.0 -0.45 -0.3433 -0.7645 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F10 mock treatment 871770.0 -62900.0 -0.34 676156.0 -55100.0 -0.31 -0.4626 -0.9987 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F11 compound treatment 937307.0 2610.0 0.01 713284.0 -18000.0 -0.1 -0.0616 -0.6018 3625616 CBKinase1_015069 CC(C)(Oc1ccc(Cl)cc1)C(=O)NCc2ccccn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F12 compound treatment 865989.0 -68700.0 -0.38 729846.0 -1420.0 -0.01 -0.2709 -0.722 3625617 CBKinase1_015070 Cc1cccnc1NC(=S)NC(=O)c2cncc(Br)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F13 compound treatment 964206.0 29500.0 0.16 657229.0 -74000.0 -0.42 -0.1812 -0.405 3625618 CBKinase1_015071 COC(=O)c1cc(OC)c(OC)cc1NC(=O)COc2ccc(C)cc2Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F14 compound treatment 983284.0 48600.0 0.27 678301.0 -53000.0 -0.3 -0.0235 -0.0589 3625619 CBKinase1_015072 Cc1cc2ccccc2n3c(SCC(=O)Nc4cccc(c4)C(F)(F)F)nnc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F15 compound treatment 835430.0 -99300.0 -0.54 587056.0 -144000.0 -0.81 -0.958 -0.9806 3625620 CBKinase1_015073 CC(=O)Nc1ccccc1NC(=O)Cc2ccccc2[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F16 compound treatment 885743.0 -49000.0 -0.27 636999.0 -94300.0 -0.53 -0.5647 -0.9494 3625621 CBKinase1_015074 Brc1ccc(cc1)C(=O)CSc2nc3ccccc3c(=O)n2Cc4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F17 mock treatment 817049.0 -118000.0 -0.64 675282.0 -56000.0 -0.32 -0.6773 -0.9464 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F18 mock treatment 692662.0 -242000.0 -1.32 679310.0 -52000.0 -0.29 -1.1414 -0.8433 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F19 compound treatment 751790.0 -183000.0 -1.0 597264.0 -134000.0 -0.76 -1.2402 -0.9905 3625622 CBKinase1_015075 COc1cc(Cl)c(C)cc1NC(=O)Cc2ccccc2[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F20 compound treatment 668848.0 -266000.0 -1.45 578803.0 -152000.0 -0.86 -1.6339 -0.9687 3625623 CBKinase1_015076 CCc1ccccc1OCC(=O)Nc2ccc(C)cc2[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F21 compound treatment 724840.0 -210000.0 -1.15 636867.0 -94400.0 -0.53 -1.1864 -0.9392 3625624 CBKinase1_015077 Clc1ccc(OCCCCSc2ncccn2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F22 compound treatment 733326.0 -201000.0 -1.1 634574.0 -96700.0 -0.54 -1.1628 -0.9476 3625625 CBKinase1_015078 O=C(CCN1C(=O)c2ccccc2C1=O)Nc3ccc(NC(=O)c4ccco4)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F23 compound treatment 592501.0 -342000.0 -1.87 597317.0 -134000.0 -0.75 -1.8549 -0.9205 3625626 CBKinase1_015079 COc1cc(OC)c(NC(=O)Cc2ccccc2[N+](=O)[O-])cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 F24 compound treatment 374441.0 -560000.0 -3.06 544615.0 -187000.0 -1.05 -2.9067 -0.8986 3625627 CBKinase1_015080 COc1ccc(cc1)C(=O)Nc2ccc(cc2)C(=O)OCc3cccc(c3)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G01 compound treatment 862871.0 -71800.0 -0.39 869343.0 138000.0 0.78 0.273 0.3133 3625628 CBKinase1_015081 Cc1cc(NC(=O)CCCN2C(=O)c3cccc4cccc(C2=O)c34)n(n1)c5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G02 compound treatment 883354.0 -51300.0 -0.28 732650.0 1390.0 0.01 -0.1927 -0.6871 3625629 CBKinase1_015082 FC(F)(F)c1ccc(Cl)c(NC(=O)CSc2nnc(o2)c3ccc(Br)cc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G03 mock treatment 862844.0 -71900.0 -0.39 815621.0 84400.0 0.48 0.0588 0.0954 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G04 mock treatment 902233.0 -32500.0 -0.18 815180.0 83900.0 0.47 0.2091 0.414 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G05 compound treatment 780821.0 -154000.0 -0.84 733012.0 1750.0 0.01 -0.5871 -0.6988 3625630 CBKinase1_015083 COc1cc(NC(=S)NCCc2c[nH]c3ccccc23)c(OC)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G06 compound treatment 940757.0 6060.0 0.03 827479.0 96200.0 0.54 0.4069 0.7488 3026510 CBKinase1_015084 FC(F)(F)c1ccc(NC(=O)c2ccc(Cn3cc(Br)cn3)o2)c(Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G07 compound treatment 346395.0 -588000.0 -3.21 262948.0 -468000.0 -2.64 -4.1376 -0.9953 1309428 CBKinase1_015085 OC(CNC1CCCC1)Cn2c3ccccc3c4ccccc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G08 compound treatment 1012010.0 77300.0 0.42 937040.0 206000.0 1.16 1.1186 0.9063 3625631 CBKinase1_015086 NCCc1c[nH]c2ccc(OCC(=O)O)cc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G09 compound treatment 884144.0 -50600.0 -0.28 905863.0 175000.0 0.98 0.5007 0.4899 1873465 CBKinase1_015087 Fc1ccccc1C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccccc3C(=O)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G10 compound treatment 989095.0 54400.0 0.3 879211.0 148000.0 0.83 0.7996 0.9034 3625632 CBKinase1_015088 Cc1ccccc1CN(CC(=O)N)S(=O)(=O)c2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G11 compound treatment 927619.0 -7080.0 -0.04 862845.0 132000.0 0.74 0.4971 0.6694 3625633 CBKinase1_015089 FC(F)(F)c1ccc(N2CCOCC2)c(NC(=O)COc3ccc(Br)cc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G12 compound treatment 1027026.0 92300.0 0.5 930417.0 199000.0 1.12 1.1502 0.9347 3625634 CBKinase1_015090 COc1ccc(C)cc1NC(=O)CN(C)S(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G13 compound treatment 958310.0 23600.0 0.13 984125.0 253000.0 1.43 1.0989 0.7679 1286750 CBKinase1_015091 Cc1ccc2n(CC(O)CN3C(=O)CNC3=O)c(c(c4ccccc4)c2c1)c5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G14 compound treatment 968971.0 34300.0 0.19 927485.0 196000.0 1.11 0.9144 0.8152 3625635 CBKinase1_015092 CCOc1ccccc1OCC(=O)Nc2cccc(c2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G15 compound treatment 918898.0 -15800.0 -0.09 933553.0 202000.0 1.14 0.7452 0.6517 3625636 CBKinase1_015093 CCn1c(SCC(=O)Nc2cc(Cl)cc(Cl)c2)nnc1c3cccs3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G16 compound treatment 971192.0 36500.0 0.2 882506.0 151000.0 0.85 0.7437 0.8495 3625637 CBKinase1_015094 CC1C2N(C(C(C)C1=O)c3ccco3)C(=O)C4C(C5OC42C=C5)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G17 compound treatment 957510.0 22800.0 0.12 926128.0 195000.0 1.1 0.8647 0.7823 3625638 CBKinase1_015095 NS(=O)(=O)c1ccc(NC(=S)NCCc2c[nH]c3ccccc23)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G18 compound treatment 894826.0 -39900.0 -0.22 960920.0 230000.0 1.29 0.7614 0.58 3625639 CBKinase1_015096 CCOc1ccc(NC2=NC(=O)C(CC(=O)Nc3ccc(OC)cc3)S2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G19 mock treatment 798900.0 -136000.0 -0.74 771315.0 40100.0 0.23 -0.3646 -0.4705 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G20 mock treatment 844638.0 -90100.0 -0.49 773434.0 42200.0 0.24 -0.1796 -0.3289 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G21 compound treatment 819966.0 -115000.0 -0.63 778827.0 47600.0 0.27 -0.2534 -0.3719 3625640 CBKinase1_015097 CCc1cccc(C)c1NC(=O)CN(C)S(=O)(=O)c2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G22 compound treatment 812571.0 -122000.0 -0.67 793770.0 62500.0 0.35 -0.2223 -0.2948 3625641 CBKinase1_015098 CCOc1ccc(NC(=O)C(C)Sc2nc3ccccc3s2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G23 compound treatment 776883.0 -158000.0 -0.86 767432.0 36200.0 0.2 -0.4651 -0.5253 3625642 CBKinase1_015099 Cc1nnc(SCC(=O)Nc2ccc(cc2)[N+](=O)[O-])s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 G24 compound treatment 484095.0 -451000.0 -2.46 706352.0 -24900.0 -0.14 -1.8388 -0.7463 3625643 CBKinase1_015100 Cc1ccc(cc1NC(=O)CSc2nnc(o2)c3ccc(Br)cc3)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H01 compound treatment 823901.0 -111000.0 -0.6 806427.0 75200.0 0.42 -0.1282 -0.1735 1870200 CBKinase1_015101 COc1ccc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(Br)cc3)cc2)nn1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H02 compound treatment 947714.0 13000.0 0.07 809718.0 78500.0 0.44 0.3629 0.8103 1625958 CBKinase1_015102 Cc1cccc(C)c1OCC(=O)Nc2cccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H03 mock treatment 951103.0 16400.0 0.09 815014.0 83700.0 0.47 0.3971 0.8265 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H04 mock treatment 1003240.0 68500.0 0.37 835633.0 104000.0 0.59 0.6806 0.9761 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H05 compound treatment 957073.0 22400.0 0.12 801784.0 70500.0 0.4 0.3674 0.8836 3625644 CBKinase1_015103 COC(=O)c1c(C)c(C)sc1NC(=O)C2C(C3CC2C=C3)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H06 compound treatment 948282.0 13600.0 0.07 837011.0 106000.0 0.6 0.4739 0.789 3625645 CBKinase1_015104 Cc1ccc(cc1)c2nnc(SCC(=O)Nc3ccc(Br)c(C)c3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H07 compound treatment 969993.0 35300.0 0.19 860024.0 129000.0 0.73 0.6494 0.8649 3625646 CBKinase1_015105 OCc1ccccc1NC(=O)Cc2ccccc2[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H08 compound treatment 986201.0 51500.0 0.28 874325.0 143000.0 0.81 0.769 0.9005 3625647 CBKinase1_015106 COC(=O)c1c(NC(=O)CC2Sc3ccccc3NC2=O)sc4CC(C)CCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H09 compound treatment 986847.0 52100.0 0.28 873671.0 142000.0 0.8 0.7689 0.9028 3625648 CBKinase1_015107 Cc1cc(C)c(C)c(OCC(=O)NCCN2CCOCC2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H10 compound treatment 973702.0 39000.0 0.21 924137.0 193000.0 1.09 0.9193 0.8298 3625649 CBKinase1_015108 Cc1nnc(SCC(=O)NCC2CCCO2)s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H11 compound treatment 999778.0 65100.0 0.36 907854.0 177000.0 1.0 0.955 0.9037 1524322 CBKinase1_015109 CC(Oc1ccc(F)cc1)C(=O)Nc2sc3CCCCc3c2C(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H12 compound treatment 1086857.0 152000.0 0.83 993751.0 262000.0 1.48 1.6336 0.9628 3625650 CBKinase1_015110 FC(Cl)C(F)(F)Oc1ccc(NC(=O)CC2Nc3ccccc3NC2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H13 compound treatment 968554.0 33900.0 0.18 905785.0 175000.0 0.98 0.8263 0.8255 3625651 CBKinase1_015111 Cc1ccsc1C2N(Cc3ccco3)C(=O)C(=C2C(=O)c4ccco4)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H14 compound treatment 1034801.0 100000.0 0.55 928416.0 197000.0 1.11 1.1722 0.9466 3625652 CBKinase1_015112 Cc1cc(Br)c(NC(=O)CSc2nnc(o2)c3ccccc3)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H15 compound treatment 1015938.0 81200.0 0.44 919650.0 188000.0 1.06 1.0644 0.925 3625653 CBKinase1_015113 COC(=O)c1c(NC(=O)C(C)Oc2ccccc2F)sc3CCCc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H16 compound treatment 1019736.0 85000.0 0.46 944620.0 213000.0 1.2 1.1786 0.9143 2068543 CBKinase1_015114 CCOC(=O)c1c(NC(=O)CSc2nnc(C)s2)sc3CCCCCc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H17 compound treatment 1029500.0 94800.0 0.52 881475.0 150000.0 0.85 0.9646 0.9721 3625654 CBKinase1_015115 COc1cc2c(cc1NC(=O)Cc3ccccc3[N+](=O)[O-])oc4ccccc42 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H18 compound treatment 980004.0 45300.0 0.25 900809.0 170000.0 0.96 0.8506 0.8617 3625655 CBKinase1_015116 [O-][N+](=O)c1ccc2C(=O)N(CCC(=O)Nc3ccccc3I)C(=O)c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H19 mock treatment 917914.0 -16800.0 -0.09 810313.0 79000.0 0.45 0.2503 0.5502 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H20 mock treatment 920190.0 -14500.0 -0.08 771619.0 40400.0 0.23 0.1048 0.4352 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H21 compound treatment 840462.0 -94200.0 -0.51 743036.0 11800.0 0.07 -0.3169 -0.6109 3625656 CBKinase1_015117 Cc1cc(C)c(C)c(OCC(=O)NCc2ccco2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H22 compound treatment 881378.0 -53300.0 -0.29 849062.0 118000.0 0.66 0.2636 0.3637 3625657 CBKinase1_015118 Cc1ccc(OCC(=O)Nc2ncccn2)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H23 compound treatment 986596.0 51900.0 0.28 822652.0 91400.0 0.52 0.5646 0.9604 1874949 CBKinase1_015119 O=C(NCc1cccnc1)c2c(NC(=O)c3ccco3)sc4CCCCc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 H24 compound treatment 868005.0 -66700.0 -0.36 742582.0 11300.0 0.06 -0.2124 -0.5745 3625658 CBKinase1_015120 CN(C)S(=O)(=O)c1ccc(Cl)c(c1)C(=O)Nc2ccccc2[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I01 compound treatment 1030410.0 95700.0 0.52 780982.0 49700.0 0.28 0.5676 0.9573 3625659 CBKinase1_015121 Cc1nnc(SCC(=O)Nc2cccc3ccccc23)s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I02 compound treatment 1040455.0 106000.0 0.58 638666.0 -92600.0 -0.52 0.0392 0.0504 3625660 CBKinase1_015122 CN(CC(=O)O)S(=O)(=O)c1cc(Cl)ccc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I03 compound treatment 1023060.0 88400.0 0.48 680211.0 -51100.0 -0.29 0.1376 0.245 3625661 CBKinase1_015123 Cc1nnc(SCC(=O)Nc2ccccc2C(F)(F)F)s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I04 compound treatment 1048888.0 114000.0 0.62 666469.0 -64800.0 -0.37 0.1826 0.2527 3625662 CBKinase1_015124 CC(=O)c1ccc(NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I05 mock treatment 1075921.0 141000.0 0.77 815479.0 84200.0 0.47 0.8808 0.9728 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I06 mock treatment 1059576.0 125000.0 0.68 689942.0 -41300.0 -0.23 0.3174 0.4405 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I07 compound treatment 971528.0 36800.0 0.2 666194.0 -65100.0 -0.37 -0.1172 -0.2801 3625663 CBKinase1_015125 Cc1ccc(cc1)S(=O)(=O)NC2C(Sc3nnnn3c4ccccc4)c5cccc6cccc2c56 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I08 compound treatment 1088883.0 154000.0 0.84 703014.0 -28300.0 -0.16 0.4826 0.5634 3625664 CBKinase1_015126 Cc1cccc(C)c1OC(=O)CCN2C(=O)C3C(C4C=CC3C5CC54)C2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I09 compound treatment 1051907.0 117000.0 0.64 729885.0 -1380.0 -0.01 0.447 0.6985 3625665 CBKinase1_015127 CN(CC(=O)Nc1c(F)cccc1F)S(=O)(=O)c2ccc(C)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I10 compound treatment 1114412.0 180000.0 0.98 741246.0 9980.0 0.06 0.7336 0.7464 3625666 CBKinase1_015128 O=C(CCN1C(=O)c2cccc3cccc(C1=O)c23)N4CCN(CC4)c5ncccn5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I11 compound treatment 1083079.0 148000.0 0.81 735165.0 3900.0 0.02 0.5884 0.726 3625667 CBKinase1_015129 CC(C)(C)c1ccc(cc1)S(=O)(=O)NCc2cccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I12 compound treatment 1091932.0 157000.0 0.86 804939.0 73700.0 0.42 0.9006 0.9445 3625668 CBKinase1_015130 Cn1c(SCC(=O)Nc2ccc3c(c2)oc4ccccc43)nnc1c5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I13 compound treatment 1067113.0 132000.0 0.72 658306.0 -73000.0 -0.41 0.2204 0.265 3625669 CBKinase1_015131 Cc1sc2ncnc(SCC(=O)NC3CCCCC3)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I14 compound treatment 1107534.0 173000.0 0.94 756913.0 25600.0 0.14 0.7694 0.806 3625670 CBKinase1_015132 COc1cc(OC)nc(NC(=O)CSc2nc3ccccc3s2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I15 compound treatment 1142298.0 208000.0 1.13 689295.0 -42000.0 -0.24 0.6342 0.5477 3625671 CBKinase1_015133 COc1ccc(NC(=O)CNS(=O)(=O)c2ccccc2)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I16 compound treatment 1061718.0 127000.0 0.69 721516.0 -9750.0 -0.05 0.4515 0.649 3625672 CBKinase1_015134 CS(=O)(=O)N(CC(=O)Nc1ccc(F)c(Cl)c1)Cc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I17 compound treatment 1075852.0 141000.0 0.77 859295.0 128000.0 0.72 1.0552 0.9995 3625673 CBKinase1_015135 CC(=O)Nc1c(O)nc(SCC(=O)N2CCN(CC2)c3ccc(F)cc3)[nH]c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I18 compound treatment 1322900.0 388000.0 2.12 766944.0 35700.0 0.2 1.6408 0.7707 3625674 CBKinase1_015136 CCOC(=O)c1c(NC(=O)c2ccc(Cn3cc(Br)cn3)o2)sc4CCCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I19 compound treatment 969481.0 34800.0 0.19 668444.0 -62800.0 -0.35 -0.1161 -0.2889 3625675 CBKinase1_015137 Oc1ccnc(SCC(=O)N2CCCc3ccccc23)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I20 compound treatment 1024591.0 89900.0 0.49 665909.0 -65400.0 -0.37 0.0866 0.141 3625676 CBKinase1_015138 CCn1c(SCC(=O)Nc2cccc(OC)c2)nnc1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I21 mock treatment 993927.0 59200.0 0.32 640515.0 -90700.0 -0.51 -0.133 -0.2198 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I22 mock treatment 985838.0 51100.0 0.28 684867.0 -46400.0 -0.26 0.0125 0.0327 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I23 compound treatment 888372.0 -46300.0 -0.25 667097.0 -64200.0 -0.36 -0.4346 -0.9847 3625677 CBKinase1_015139 Cc1nnc(Nc2ccc(OCC(=O)N3CCN(CC3)c4ccccc4)cc2)c5ccccc15 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 I24 compound treatment 979427.0 44700.0 0.24 685594.0 -45700.0 -0.26 -0.0093 -0.0263 3625678 CBKinase1_015140 CN(CC(=O)Nc1cccc(c1)C(=O)C)S(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J01 compound treatment 1035895.0 101000.0 0.55 529452.0 -202000.0 -1.14 -0.4137 -0.3271 3625679 CBKinase1_015141 O=C(CN1CCCCC1)Nc2ccc(NC(=O)CN3CCCCC3)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J02 compound treatment 1008452.0 73800.0 0.4 679573.0 -51700.0 -0.29 0.0787 0.1584 3625680 CBKinase1_015142 OC(=O)c1cccc(NC(=O)c2ccc3C(=O)N(Cc4cccnc4)C(=O)c3c2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J03 compound treatment 1040118.0 105000.0 0.58 757125.0 25900.0 0.15 0.51 0.8591 3625681 CBKinase1_015143 Cc1ccc(cc1)N(Cc2cc3ccccc3nc2O)C(=O)c4cccnc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J04 compound treatment 1008637.0 73900.0 0.4 751882.0 20600.0 0.12 0.3676 0.8751 3625682 CBKinase1_015144 O=C(CN1C(=O)C2C(C3C=CC2C4CC43)C1=O)Oc5ccccc5C(=O)Oc6ccccc6 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J05 mock treatment 989109.0 54400.0 0.3 726794.0 -4470.0 -0.03 0.1922 0.6448 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J06 mock treatment 1005443.0 70700.0 0.39 707841.0 -23400.0 -0.13 0.1798 0.4404 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J07 compound treatment 1005917.0 71200.0 0.39 748196.0 16900.0 0.1 0.3424 0.8553 3625683 CBKinase1_015145 OC1=C(C(N(Cc2ccco2)C1=O)c3cccc(Cl)c3)C(=O)c4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J08 compound treatment 1059973.0 125000.0 0.68 741354.0 10100.0 0.06 0.5238 0.7633 3625684 CBKinase1_015146 Cc1ccc(F)cc1NC(=O)CSc2nnc(o2)c3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J09 compound treatment 1094861.0 160000.0 0.87 744182.0 12900.0 0.07 0.6698 0.7633 3625685 CBKinase1_015147 OC1=C(C(N(Cc2ccco2)C1=O)c3cccc(O)c3)C(=O)c4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J10 compound treatment 1081480.0 147000.0 0.8 832834.0 102000.0 0.57 0.9715 0.9864 3625686 CBKinase1_015148 CN(CC(=O)Nc1ccc(Cl)cc1)S(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J11 compound treatment 1090796.0 156000.0 0.85 811985.0 80700.0 0.45 0.9243 0.9568 3625687 CBKinase1_015149 Cc1ccc(C)c(OCC(=O)Nc2cccc(Oc3ccc4C(=O)NC(=O)c4c3)c2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J12 compound treatment 1136365.0 202000.0 1.1 814458.0 83200.0 0.47 1.1101 0.9276 3625688 CBKinase1_015150 O=S(=O)(NCc1ccco1)c2ccc(Oc3ccccc3)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J13 compound treatment 1117608.0 183000.0 1.0 837532.0 106000.0 0.6 1.1296 0.9701 3625689 CBKinase1_015151 OC1=C(C(N(Cc2ccco2)C1=O)c3cccc(Oc4ccccc4)c3)C(=O)c5cccs5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J14 compound treatment 1119939.0 185000.0 1.01 763478.0 32200.0 0.18 0.8435 0.8209 3625690 CBKinase1_015152 COc1ccc(cc1NC(=O)C2(CCCCC2)c3ccc(OC)c(OC)c3)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J15 compound treatment 1116911.0 182000.0 0.99 825696.0 94400.0 0.53 1.0798 0.9571 3625691 CBKinase1_015153 Cc1ccc(cc1)S(=O)(=O)c2nc(SCC(=O)c3ccc(Cl)cc3)sc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J16 compound treatment 1160216.0 226000.0 1.23 868691.0 137000.0 0.77 1.4183 0.9751 3625692 CBKinase1_015154 O=C(CSc1nnc2scc(c3ccccc3)n12)Nc4nsc(n4)c5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J17 compound treatment 1093543.0 159000.0 0.87 705776.0 -25500.0 -0.14 0.5116 0.582 3625693 CBKinase1_015155 CC(C)(Oc1ccc(Cl)cc1)C(=O)NCc2ccco2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J18 compound treatment 1052338.0 118000.0 0.64 727409.0 -3860.0 -0.02 0.4388 0.6828 3625694 CBKinase1_015156 Cn1c(SCC(=O)Nc2ccc(Br)cc2)nnc1c3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J19 compound treatment 1088913.0 154000.0 0.84 763748.0 32500.0 0.18 0.7248 0.8412 3625695 CBKinase1_015157 Cc1ccc(o1)C(=O)C2=C(O)C(=O)N(Cc3ccco3)C2c4ccc(F)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J20 compound treatment 1060159.0 125000.0 0.68 710247.0 -21000.0 -0.12 0.4006 0.5763 3625696 CBKinase1_015158 OC(=O)c1cc(NC(=S)NC(=O)c2cccc(COc3ccccc3)c2)ccc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J21 mock treatment 1040601.0 106000.0 0.58 735873.0 4610.0 0.03 0.4272 0.7381 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J22 mock treatment 929914.0 -4780.0 -0.03 713935.0 -17300.0 -0.1 -0.0875 -0.8658 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J23 compound treatment 966980.0 32300.0 0.18 744736.0 13500.0 0.08 0.1783 0.9292 3625697 CBKinase1_015159 Cc1ccc(OCC(=O)NCCN2CCOCC2)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 J24 compound treatment 873366.0 -61300.0 -0.33 677692.0 -53600.0 -0.3 -0.4503 -0.9987 3625698 CBKinase1_015160 Cc1ccc(O)c(NC(=O)CCCOc2ccc(Cl)cc2Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K01 compound treatment 760087.0 -175000.0 -0.95 642789.0 -88500.0 -0.5 -1.0267 -0.9543 3625699 CBKinase1_015161 CC(=O)c1cccc(NC(=O)CN(Cc2ccccc2)S(=O)(=O)C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K02 compound treatment 841332.0 -93400.0 -0.51 653840.0 -77400.0 -0.44 -0.669 -0.997 3625700 CBKinase1_015162 Brc1ccc(cc1)c2nnc(SCC(=O)Nc3ccc4ccccc4c3)o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K03 compound treatment 964306.0 29600.0 0.16 663325.0 -67900.0 -0.38 -0.1565 -0.3765 1399964 CBKinase1_015163 Brc1cccc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K04 compound treatment 878063.0 -56600.0 -0.31 687229.0 -44000.0 -0.25 -0.3941 -0.9941 1740818 CBKinase1_015164 COc1ccccc1NC(=O)c2ccc(OCC(=O)O)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K05 compound treatment 926662.0 -8040.0 -0.04 613545.0 -118000.0 -0.66 -0.5002 -0.7522 3625701 CBKinase1_015165 CC(=O)Nc1cccc(c1)c2nnc(SCC(=O)N3CCN(CC3)c4ccccc4)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K06 compound treatment 899173.0 -35500.0 -0.19 634412.0 -96900.0 -0.55 -0.5232 -0.903 3625702 CBKinase1_015166 COc1ccccc1NC(=O)CSc2nnc(c3ccc(Br)cc3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K07 mock treatment 951026.0 16300.0 0.09 663640.0 -67600.0 -0.38 -0.2065 -0.5275 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K08 mock treatment 1019305.0 84600.0 0.46 619336.0 -112000.0 -0.63 -0.1195 -0.1528 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K09 compound treatment 954434.0 19700.0 0.11 813808.0 82500.0 0.47 0.4052 0.8484 1878325 CBKinase1_015167 Cc1cc(C)n(n1)S(=O)(=O)c2cc(C(=O)O)c(Cl)cc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K10 compound treatment 989504.0 54800.0 0.3 760424.0 29200.0 0.16 0.3278 0.9602 3625703 CBKinase1_015168 CCn1c(SCC(=O)N)nnc1c2ccncc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K11 compound treatment 962006.0 27300.0 0.15 776191.0 44900.0 0.25 0.2845 0.9681 3625704 CBKinase1_015169 [O-][N+](=O)c1cccc(NC(=O)CNS(=O)(=O)c2ccccc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K12 compound treatment 958612.0 23900.0 0.13 657029.0 -74200.0 -0.42 -0.2035 -0.4644 3625705 CBKinase1_015170 CCc1cccc(C)c1NC(=O)CN(C)S(=O)(=O)c2ccc(Br)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K13 compound treatment 931801.0 -2900.0 -0.02 678705.0 -52600.0 -0.3 -0.2207 -0.7438 1320012 CBKinase1_015171 Cc1ccc(CNC(=O)c2cccc(Cn3cc(Cl)cn3)c2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K14 compound treatment 1023381.0 88700.0 0.48 807361.0 76100.0 0.43 0.6456 0.9982 3625706 CBKinase1_015172 CN(CC(=O)Nc1ccc(F)cc1F)S(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K15 mock treatment 913215.0 -21500.0 -0.12 757285.0 26000.0 0.15 0.0208 0.1106 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K16 mock treatment 929149.0 -5550.0 -0.03 674866.0 -56400.0 -0.32 -0.2462 -0.771 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K17 compound treatment 1018036.0 83300.0 0.45 681129.0 -50100.0 -0.28 0.1219 0.2276 3625707 CBKinase1_015173 COc1cc(NC(=S)NCc2cccnc2)c(OC)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K18 compound treatment 979431.0 44700.0 0.24 801478.0 70200.0 0.4 0.4525 0.9731 3625708 CBKinase1_015174 CC1=C(C(c2ccco2)n3ncnc3N1)C(=O)Nc4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K19 compound treatment 890924.0 -43800.0 -0.24 596258.0 -135000.0 -0.76 -0.7071 -0.8865 3625709 CBKinase1_015175 Cn1c(SCC(=O)Nc2ccccc2C(F)(F)F)nnc1c3cccc(N)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K20 compound treatment 963531.0 28800.0 0.16 719157.0 -12100.0 -0.07 0.0631 0.3675 3625710 CBKinase1_015176 Cc1ccccc1c2nc(C#N)c(NCCN3CCOCC3)o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K21 compound treatment 879974.0 -54700.0 -0.3 584929.0 -146000.0 -0.82 -0.7945 -0.9057 3625711 CBKinase1_015177 [O-][N+](=O)c1ccc(cc1NCc2ccco2)N3CCN(CC3)S(=O)(=O)c4ccc(F)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K22 compound treatment 839219.0 -95500.0 -0.52 661709.0 -69600.0 -0.39 -0.6458 -0.9901 3625712 CBKinase1_015178 CC(C)c1ccc(NC(=O)CNS(=O)(=O)c2ccccc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K23 mock treatment 904972.0 -29700.0 -0.16 697456.0 -33800.0 -0.19 -0.2495 -0.9968 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 K24 mock treatment 729133.0 -206000.0 -1.12 647590.0 -83700.0 -0.47 -1.1271 -0.9258 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L01 compound treatment 1135960.0 201000.0 1.1 677931.0 -53300.0 -0.3 0.5644 0.4954 1862959 CBKinase1_015179 [O-][N+](=O)c1ccc(OCC(=O)Nc2ccc3oc(nc3c2)c4cc(F)c(F)cc4Cl)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L02 compound treatment 941800.0 7100.0 0.04 716621.0 -14600.0 -0.08 -0.0309 -0.3393 3625713 CBKinase1_015180 Cc1c(NC(=O)CCCC(=O)O)cccc1C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L03 compound treatment 952214.0 17500.0 0.1 680359.0 -50900.0 -0.29 -0.1353 -0.4472 3625714 CBKinase1_015181 Clc1cccc(NC(=O)C(=O)NCc2ccccn2)c1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L04 compound treatment 1018338.0 83600.0 0.46 828826.0 97600.0 0.55 0.7117 0.9957 1479695 CBKinase1_015182 CCOC(=O)c1c(NC(=O)c2cc(ccc2OC)S(=O)(=O)N3CCOCC3)sc4CCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L05 compound treatment 971873.0 37200.0 0.2 686590.0 -44700.0 -0.25 -0.0345 -0.1068 3625715 CBKinase1_015183 CCCC(=O)N(Cc1cc2cccc(C)c2nc1O)c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L06 compound treatment 935753.0 1060.0 0.01 657300.0 -74000.0 -0.42 -0.2907 -0.6973 3625716 CBKinase1_015184 Cc1cccc(NC(=O)Cn2nc(c3ccc(Cl)cc3)c4ccccc4c2=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L07 mock treatment 1013285.0 78600.0 0.43 764224.0 33000.0 0.19 0.4347 0.9299 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L08 mock treatment 1070095.0 135000.0 0.74 741421.0 10200.0 0.06 0.5632 0.7596 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L09 compound treatment 874205.0 -60500.0 -0.33 652992.0 -78300.0 -0.44 -0.5455 -0.9898 3625717 CBKinase1_015185 COC(=O)c1c(C)c(sc1NC(=O)C(C)Oc2ccc(F)cc2)C(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L10 compound treatment 883765.0 -50900.0 -0.28 699253.0 -32000.0 -0.18 -0.3242 -0.9781 3625718 CBKinase1_015186 Cc1ccc(O)c(CNc2nc3ccccc3n2CC=C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L11 compound treatment 1096987.0 162000.0 0.89 794366.0 63100.0 0.36 0.878 0.9196 3625719 CBKinase1_015187 COC(=O)c1ccccc1NC(=O)C(C)Oc2ccccc2F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L12 compound treatment 1066599.0 132000.0 0.72 760356.0 29100.0 0.16 0.6251 0.8464 1315657 CBKinase1_015188 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccncc3)S(=O)(=O)c4ccc(OC)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L13 compound treatment 1058563.0 124000.0 0.68 716787.0 -14500.0 -0.08 0.4205 0.6173 3625720 CBKinase1_015189 OC1=C(C(N(Cc2ccco2)C1=O)c3cccs3)C(=O)c4cccs4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L14 compound treatment 1000410.0 65700.0 0.36 774238.0 43000.0 0.24 0.425 0.9817 3625721 CBKinase1_015190 CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3cc(ccc3C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L15 mock treatment 1039782.0 105000.0 0.57 705523.0 -25700.0 -0.15 0.3031 0.5122 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L16 mock treatment 1010508.0 75800.0 0.41 730577.0 -688.0 0.0 0.2899 0.7005 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L17 compound treatment 693042.0 -242000.0 -1.32 511312.0 -220000.0 -1.24 -1.8095 -0.9995 1355760 CBKinase1_015191 Cc1ccnc(NC(c2ccccn2)c3ccc4ccc(C)nc4c3O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L18 compound treatment 1008682.0 74000.0 0.4 706527.0 -24700.0 -0.14 0.187 0.4377 3625722 CBKinase1_015192 Cc1ccc(cn1)C(=O)NCCCn2ccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L19 compound treatment 1003348.0 68700.0 0.37 728647.0 -2620.0 -0.01 0.2546 0.6787 3625723 CBKinase1_015193 COc1ccc(NC(=O)Cc2ccccc2[N+](=O)[O-])cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L20 compound treatment 946619.0 11900.0 0.07 698223.0 -33000.0 -0.19 -0.0857 -0.4342 3625724 CBKinase1_015194 COc1ccccc1CNC(=O)c2cccc(NC(=O)c3ccccc3)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L21 compound treatment 928060.0 -6640.0 -0.04 706664.0 -24600.0 -0.14 -0.1237 -0.8629 3625725 CBKinase1_015195 Cc1cccc(C)c1OCC(=O)Nc2ccccc2C(=O)Nc3ccc(cc3)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L22 compound treatment 926499.0 -8200.0 -0.04 692631.0 -38600.0 -0.22 -0.1856 -0.835 3625726 CBKinase1_015196 [O-][N+](=O)c1ccccc1S(=O)(=O)c2ccccc2C(=O)Nc3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L23 mock treatment 911988.0 -22700.0 -0.12 663521.0 -67700.0 -0.38 -0.3577 -0.8909 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 L24 mock treatment 974551.0 39900.0 0.22 599283.0 -132000.0 -0.74 -0.3722 -0.4802 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M01 compound treatment 852115.0 -82600.0 -0.45 571585.0 -160000.0 -0.9 -0.9552 -0.9489 3625727 CBKinase1_015197 COc1ccc(NC(=O)CSc2nnc(c3cccs3)n2c4ccc(F)cc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M02 compound treatment 830236.0 -104000.0 -0.57 775753.0 44500.0 0.25 -0.226 -0.3627 3625728 CBKinase1_015198 CC(=O)Nc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(c3)C(F)(F)F)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M03 compound treatment 638574.0 -296000.0 -1.62 807396.0 76100.0 0.43 -0.8397 -0.502 3625729 CBKinase1_015199 CN(CC(=O)Nc1ccc(NC(=O)C)cc1)S(=O)(=O)c2ccc(Br)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M04 compound treatment 1037753.0 103000.0 0.56 839303.0 108000.0 0.61 0.8284 0.9992 3625730 CBKinase1_015200 Cc1ccc(cc1)N(C2CS(=O)(=O)C=C2)C(=O)COc3ccccc3[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M05 compound treatment 984088.0 49400.0 0.27 789904.0 58600.0 0.33 0.4244 0.9949 3625731 CBKinase1_015201 CC(=O)Nc1cccc(c1)c2nnc(SCC(=O)Nc3ccc(cc3)C(=O)C)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M06 compound treatment 917697.0 -17000.0 -0.09 839848.0 109000.0 0.61 0.3671 0.5931 3625732 CBKinase1_015202 COc1ccc(cc1OC)S(=O)(=O)N2CCC(CC2)C(=O)Nc3ccc(NC(=O)C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M07 compound treatment 988136.0 53400.0 0.29 810940.0 79700.0 0.45 0.5238 0.9782 3625733 CBKinase1_015203 FC(F)(F)c1ccccc1NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M08 compound treatment 1027619.0 92900.0 0.51 901231.0 170000.0 0.96 1.0361 0.9558 1153657 CBKinase1_015204 COc1cc(C)c(cc1C)S(=O)(=O)NCCc2c(C)[nH]c3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M09 mock treatment 970542.0 35800.0 0.2 869305.0 138000.0 0.78 0.6885 0.8582 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M10 mock treatment 978850.0 44200.0 0.24 875863.0 145000.0 0.82 0.7468 0.8786 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M11 compound treatment 998497.0 63800.0 0.35 874779.0 144000.0 0.81 0.8183 0.9291 1216323 CBKinase1_015205 CCOC(=O)C1=C(C)Nc2ncnn2C1c3ccccn3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M12 compound treatment 1004007.0 69300.0 0.38 882418.0 151000.0 0.85 0.87 0.9333 3625734 CBKinase1_015206 Cc1cccc(OCC(=O)Nc2cccc(c2)c3nnc(o3)c4ccco4)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M13 mock treatment 1008888.0 74200.0 0.41 848226.0 117000.0 0.66 0.7526 0.9726 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M14 mock treatment 952015.0 17300.0 0.09 880311.0 149000.0 0.84 0.6609 0.7817 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M15 compound treatment 972074.0 37400.0 0.2 890856.0 160000.0 0.9 0.7803 0.846 3625735 CBKinase1_015207 Cn1c(SCC(=O)c2ccc(F)cc2)nnc1c3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M16 compound treatment 965444.0 30700.0 0.17 863026.0 132000.0 0.74 0.6438 0.8456 3026563 CBKinase1_015208 Cn1cc(Cl)c(n1)C(=O)NCC(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M17 compound treatment 957858.0 23200.0 0.13 874411.0 143000.0 0.81 0.6599 0.8081 3625736 CBKinase1_015209 CC(C)c1cccc(C(C)C)c1NC(=O)Cn2cnc3sc(C)c(C)c3c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M18 compound treatment 989353.0 54700.0 0.3 895340.0 164000.0 0.92 0.8649 0.8901 3625737 CBKinase1_015210 Cc1cc(ccc1NC(=O)COc2ccccc2Cl)C(=O)Nc3ccccc3C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M19 compound treatment 933135.0 -1560.0 -0.01 765267.0 34000.0 0.19 0.1295 0.675 3625738 CBKinase1_015211 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3ccc(cc3)C(=O)N4CCCCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M20 compound treatment 970517.0 35800.0 0.2 816748.0 85500.0 0.48 0.479 0.9211 1861573 CBKinase1_015212 CCCn1nnnc1NC(=O)COc2ccc(Cl)c(C)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M21 compound treatment 915987.0 -18700.0 -0.1 810594.0 79300.0 0.45 0.2439 0.5319 3625739 CBKinase1_015213 CCOC(=O)C1=C(C)Nc2ncnn2C1c3c[nH]c4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M22 compound treatment 951832.0 17100.0 0.09 908826.0 178000.0 1.0 0.7738 0.7698 3625740 CBKinase1_015214 COC(=O)c1sc2nc(nc(Nc3nc(C)cc(C)n3)c2c1C)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M23 compound treatment 949402.0 14700.0 0.08 776222.0 45000.0 0.25 0.2359 0.8876 3625741 CBKinase1_015215 [O-][N+](=O)c1ccc(cc1)C(=O)CSc2nnc(C3COc4ccccc4O3)n2c5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 M24 compound treatment 907873.0 -26800.0 -0.15 783706.0 52400.0 0.3 0.1055 0.3197 3625742 CBKinase1_015216 CCn1c(SCc2nc(O)c3ccccc3n2)nnc1c4ccccc4Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N01 compound treatment 883470.0 -51200.0 -0.28 676554.0 -54700.0 -0.31 -0.4158 -0.9988 3625743 CBKinase1_015217 CCC(=O)N(Cc1cc2ccccc2nc1O)c3cccc(C)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N02 compound treatment 1100398.0 166000.0 0.9 782360.0 51100.0 0.29 0.8433 0.8883 3625744 CBKinase1_015218 Cc1cc(O)nc(SCC(=O)N2CCc3ccccc3C2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N03 compound treatment 902294.0 -32400.0 -0.18 778234.0 47000.0 0.26 0.0621 0.195 3625745 CBKinase1_015219 CNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3ccc(NC(=O)C)cc3)c4ccccc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N04 compound treatment 934470.0 -228.0 0.0 819604.0 88300.0 0.5 0.3512 0.7053 3625746 CBKinase1_015220 FC(F)(F)Oc1ccc(cc1)N2C(=O)CC(SCC(=O)Nc3ccc(Cl)cc3)C2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N05 compound treatment 824646.0 -110000.0 -0.6 691981.0 -39300.0 -0.22 -0.5814 -0.908 3625747 CBKinase1_015221 CCNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3ccc(NC(=O)C)cc3)c4ccccc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N06 compound treatment 1016363.0 81700.0 0.45 860762.0 129000.0 0.73 0.8314 0.972 1221802 CBKinase1_015222 CCc1ccccc1OCC(=O)Nc2cc(OC)ccc2OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N07 compound treatment 980887.0 46200.0 0.25 801470.0 70200.0 0.4 0.4581 0.9763 1875354 CBKinase1_015223 COc1cccc(c1)C(=O)Nc2sc3CCCCc3c2C(=O)NCc4cccnc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N08 compound treatment 976574.0 41900.0 0.23 865662.0 134000.0 0.76 0.6973 0.8813 1419551 CBKinase1_015224 Cc1cc(SCC(=O)N)nc2ccccc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N09 mock treatment 993075.0 58400.0 0.32 909000.0 178000.0 1.0 0.9337 0.8882 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N10 mock treatment 995272.0 60600.0 0.33 890119.0 159000.0 0.9 0.867 0.9083 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N11 compound treatment 1006504.0 71800.0 0.39 881780.0 151000.0 0.85 0.8771 0.9385 3625748 CBKinase1_015225 OC1=C(C(N(CC2CCCO2)C1=O)c3cccc(Oc4ccccc4)c3)C(=O)c5ccco5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N12 compound treatment 1005371.0 70700.0 0.39 837542.0 106000.0 0.6 0.6964 0.9774 1449048 CBKinase1_015226 COc1ccc(CCNC(=O)c2c(C)onc2c3c(F)cccc3Cl)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N13 mock treatment 1022706.0 88000.0 0.48 914528.0 183000.0 1.03 1.0702 0.9394 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N14 mock treatment 1009623.0 74900.0 0.41 895548.0 164000.0 0.93 0.944 0.9325 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N15 compound treatment 941911.0 7210.0 0.04 900590.0 169000.0 0.95 0.7027 0.7357 3625749 CBKinase1_015227 CC(Oc1ccccc1F)C(=O)Nc2ccccc2[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N16 compound treatment 1078260.0 144000.0 0.78 736711.0 5450.0 0.03 0.5759 0.7342 3625750 CBKinase1_015228 Cc1cccc(C)c1NC(=O)CSc2nnnn2c3c(C)cccc3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N17 compound treatment 1086551.0 152000.0 0.83 834092.0 103000.0 0.58 0.996 0.9847 1984149 CBKinase1_015229 CC(Oc1ccc(F)cc1)C(=O)NCCN2CCOCC2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N18 compound treatment 989316.0 54600.0 0.3 885683.0 154000.0 0.87 0.8263 0.8981 3625751 CBKinase1_015230 CCc1ccc(NC(=O)CSc2nc(C)cc(C)n2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N19 compound treatment 976427.0 41700.0 0.23 817105.0 85800.0 0.48 0.5032 0.941 3625752 CBKinase1_015231 COC(=O)c1cc(OC)c(OC)cc1NC(=O)Cc2ccccc2[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N20 compound treatment 943673.0 8980.0 0.05 777467.0 46200.0 0.26 0.2188 0.8257 3625753 CBKinase1_015232 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)c2ccccc2C(=O)Nc3cccc4cccnc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N21 compound treatment 976646.0 41900.0 0.23 814845.0 83600.0 0.47 0.4951 0.9451 3625754 CBKinase1_015233 COc1ccc(OCCCSc2ncccn2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N22 compound treatment 908928.0 -25800.0 -0.14 755566.0 24300.0 0.14 -0.0026 -0.0134 3625755 CBKinase1_015234 COc1cc(NC(=O)COc2cc(C)c(C)cc2C)c(cc1OC)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N23 compound treatment 913298.0 -21400.0 -0.12 784861.0 53600.0 0.3 0.131 0.4044 3625756 CBKinase1_015235 COc1cc(NC(=O)COc2cc(C)cc(C)c2C)c(OC)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 N24 compound treatment 1407488.0 473000.0 2.58 736502.0 5240.0 0.03 1.8461 0.7151 3625757 CBKinase1_015236 [O-][N+](=O)c1ccccc1S(=O)(=O)c2ccccc2C(=O)Oc3ccc4ccccc4c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O01 compound treatment 984705.0 50000.0 0.27 784186.0 52900.0 0.3 0.404 0.999 3625758 CBKinase1_015237 COc1ccc(cc1)c2cc(=O)[nH]c(SCc3nc(O)c4ccccc4n3)n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O02 compound treatment 865428.0 -69300.0 -0.38 729305.0 -1960.0 -0.01 -0.2752 -0.7274 3625759 CBKinase1_015238 COC(=O)c1ccccc1NC(=O)CN(C)S(=O)(=O)c2cc(Cl)ccc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O03 compound treatment 868087.0 -66600.0 -0.36 793598.0 62300.0 0.35 -0.0087 -0.0172 3625760 CBKinase1_015239 COc1ccc(OC)c(NC(=O)CSc2nnnn2c3ccccc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O04 compound treatment 908694.0 -26000.0 -0.14 796691.0 65400.0 0.37 0.1604 0.4058 3625761 CBKinase1_015240 OC(=O)C1CC=CCC1C(=O)Nc2cccc(c2)C(=O)N3CCCCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O05 compound treatment 914038.0 -20700.0 -0.11 746197.0 14900.0 0.08 -0.0202 -0.1438 3625762 CBKinase1_015241 COc1ccc(cc1)C(=O)Nc2ccc(Cl)cc2C(=O)NCCN3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O06 compound treatment 973024.0 38300.0 0.21 710809.0 -20500.0 -0.12 0.0664 0.2781 3625763 CBKinase1_015242 COc1ccc(cc1NC(=O)COc2ccc(C)cc2)c3nn(C)c(=O)c4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O07 compound treatment 980031.0 45300.0 0.25 807059.0 75800.0 0.43 0.4771 0.9663 3087026 CBKinase1_015243 O=S1(=O)N=C(NCc2ccco2)c3ccccc31 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O08 compound treatment 900815.0 -33900.0 -0.18 762225.0 31000.0 0.17 -0.0074 -0.0291 3625764 CBKinase1_015244 COc1ccc(Cl)cc1NC(=O)CN(Cc2ccccc2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O09 compound treatment 975699.0 41000.0 0.22 839886.0 109000.0 0.61 0.5912 0.9069 3625765 CBKinase1_015245 Cc1ccc(NC(=O)CNS(=O)(=O)c2ccccc2)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O10 compound treatment 991558.0 56900.0 0.31 763272.0 32000.0 0.18 0.3471 0.9667 3625766 CBKinase1_015246 COC(=O)c1ccc(NC(=O)CN(C)S(=O)(=O)c2ccccc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O11 mock treatment 979013.0 44300.0 0.24 743471.0 12200.0 0.07 0.2197 0.8736 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O12 mock treatment 936210.0 1510.0 0.01 766103.0 34800.0 0.2 0.1447 0.7362 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O13 compound treatment 988683.0 54000.0 0.29 762707.0 31400.0 0.18 0.3337 0.9704 3625767 CBKinase1_015247 Cc1ccc(cc1)N(Cc2ccco2)C(=O)c3cccc(c3)S(=O)(=O)N4CCOCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O14 compound treatment 955653.0 21000.0 0.11 784170.0 52900.0 0.3 0.2918 0.9135 3625768 CBKinase1_015248 Cc1nnc(SCC(=O)Nc2ccc(C)c(Cl)c2)s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O15 compound treatment 886472.0 -48200.0 -0.26 767326.0 36100.0 0.2 -0.0424 -0.1276 3625769 CBKinase1_015249 CCn1c(SCC(=O)Nc2ccccc2OC)nnc1c3ccc(N)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O16 compound treatment 961923.0 27200.0 0.15 740219.0 8950.0 0.05 0.1408 0.8969 3625770 CBKinase1_015250 O=C(CNS(=O)(=O)c1ccccc1)Nc2ccc3OCCOc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O17 compound treatment 978166.0 43500.0 0.24 708740.0 -22500.0 -0.13 0.078 0.2899 3625771 CBKinase1_015251 CCn1c(SCC(=O)Nc2ccccc2F)nnc1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O18 compound treatment 925724.0 -8970.0 -0.05 766274.0 35000.0 0.2 0.1049 0.5159 3625772 CBKinase1_015252 Cc1ccc(cc1)S(=O)(=O)NC2C(Sc3nnc(N)s3)c4cccc5cccc2c45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O19 compound treatment 980097.0 45400.0 0.25 758780.0 27500.0 0.16 0.2849 0.9745 3625773 CBKinase1_015253 COc1ccccc1OCC(=O)Nc2cccc(c2)c3nnc(o3)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O20 compound treatment 931992.0 -2710.0 -0.01 717414.0 -13900.0 -0.08 -0.0656 -0.8263 3625774 CBKinase1_015254 Clc1ccc(cc1)n2ncc3c(NCCCN4CCCC4=O)ncnc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O21 compound treatment 1100642.0 166000.0 0.91 863339.0 132000.0 0.74 1.167 0.9952 3625775 CBKinase1_015255 CC(=O)c1c(C)nc(nc1NC(=O)Cc2ccccc2)c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O22 compound treatment 945406.0 10700.0 0.06 790943.0 59700.0 0.34 0.2792 0.8177 3625776 CBKinase1_015256 CCn1ncc(Br)c1C(=O)Nc2ccccc2C(=O)OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O23 compound treatment 924340.0 -10400.0 -0.06 711039.0 -20200.0 -0.11 -0.1206 -0.9477 3625777 CBKinase1_015257 COc1ccc(NC(=O)CSC2=NC(CC(=O)N2)c3ccccc3)cc1Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 O24 compound treatment 910341.0 -24400.0 -0.13 725203.0 -6060.0 -0.03 -0.1182 -0.8608 3625778 CBKinase1_015258 Cc1ccc(NC(=O)CSc2nnc(o2)c3ccc(Br)cc3)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P01 compound treatment 881286.0 -53400.0 -0.29 773044.0 41800.0 0.24 -0.0397 -0.1059 1862919 CBKinase1_015259 Cc1ccc(OCC(=O)Nc2ccccc2N3CCOCC3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P02 compound treatment 912062.0 -22600.0 -0.12 804924.0 73700.0 0.42 0.2062 0.476 3625779 CBKinase1_015260 CC(=O)Oc1ccc(NC(=O)COc2ccccc2)c(c1)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P03 compound treatment 937072.0 2370.0 0.01 727582.0 -3680.0 -0.02 -0.0055 -0.2252 3625780 CBKinase1_015261 COc1ccc(cc1)N(Cc2cc3ccccc3nc2O)C(=O)c4cccc(OC)c4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P04 compound treatment 912440.0 -22300.0 -0.12 781457.0 50200.0 0.28 0.1141 0.3706 3625781 CBKinase1_015262 COc1ccccc1NC(=O)CN2C(=O)C3C4CCC(C4)C3C2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P05 compound treatment 975319.0 40600.0 0.22 741809.0 10500.0 0.06 0.1988 0.866 3625782 CBKinase1_015263 COc1ccc(OC)c(NC(=O)C2C(C3OC2C=C3)C(=O)O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P06 compound treatment 1032697.0 98000.0 0.54 717102.0 -14200.0 -0.08 0.3219 0.595 1983954 CBKinase1_015264 CCC(Sc1nnnn1c2ccccc2)C(=O)Nc3ccccc3OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P07 compound treatment 931991.0 -2710.0 -0.01 825536.0 94300.0 0.53 0.3653 0.6872 3625783 CBKinase1_015265 Cc1ccc(cc1)S(=O)(=O)c2nc(sc2NCC3CCCO3)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P08 compound treatment 839047.0 -95700.0 -0.52 818095.0 86800.0 0.49 -0.0232 -0.0324 3625784 CBKinase1_015266 CC(=O)c1c(C)oc2ccc(cc12)N(C(=O)c3ccncc3)S(=O)(=O)c4ccc(F)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P09 compound treatment 968948.0 34300.0 0.19 791269.0 60000.0 0.34 0.3714 0.961 3625785 CBKinase1_015267 COc1ccc(NC(=O)C(C)(C)Oc2ccc(Cl)cc2)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P10 compound treatment 993713.0 59000.0 0.32 721620.0 -9640.0 -0.05 0.1894 0.5796 1300567 CBKinase1_015268 Cc1c(NS(=O)(=O)c2cccc3nonc23)c(=O)n(c4ccccc4)n1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P11 mock treatment 903977.0 -30700.0 -0.17 763474.0 32200.0 0.18 0.0098 0.0395 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P12 mock treatment 1036243.0 102000.0 0.55 830356.0 99100.0 0.56 0.7869 1.0 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P13 compound treatment 1520311.0 586000.0 3.2 770823.0 39600.0 0.22 2.4184 0.7546 3625786 CBKinase1_015269 OC(=O)c1cc(NC(=O)COc2ccc(I)cc2)cc(c1)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P14 compound treatment 1047784.0 113000.0 0.62 764009.0 32700.0 0.18 0.5671 0.88 3625787 CBKinase1_015270 CCOC(=O)c1cc(CC)sc1N2C(=O)CC(Sc3ncccc3C(=O)O)C2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P15 compound treatment 999134.0 64400.0 0.35 796553.0 65300.0 0.37 0.509 0.9997 3625788 CBKinase1_015271 Cc1cccc(OCC(=O)Nc2ccccc2CO)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P16 compound treatment 1046757.0 112000.0 0.61 808787.0 77500.0 0.44 0.7416 0.9864 1356062 CBKinase1_015272 CCOC(=O)c1cnc2c(cccc2c1NCc3ccco3)C(=O)OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P17 compound treatment 925225.0 -9470.0 -0.05 828608.0 97300.0 0.55 0.3514 0.6376 3625789 CBKinase1_015273 Cc1cc(C)c(C)c(OCC(=O)NCc2ccccn2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P18 compound treatment 971160.0 36500.0 0.2 754845.0 23600.0 0.13 0.2347 0.9807 3625790 CBKinase1_015274 Cc1ccc(cc1NC(=O)CCN2C(=O)c3ccccc3C2=O)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P19 compound treatment 984692.0 50000.0 0.27 692816.0 -38400.0 -0.22 0.0398 0.1141 3625791 CBKinase1_015275 Brc1ccc(OCC(=O)NCCN2CCOCC2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P20 compound treatment 954186.0 19500.0 0.11 734678.0 3410.0 0.02 0.0888 0.8216 3625792 CBKinase1_015276 Cc1ccc(OCC(=O)Nc2cc(Cl)ccc2C(=O)O)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P21 compound treatment 986028.0 51300.0 0.28 767086.0 35800.0 0.2 0.3409 0.9871 3625793 CBKinase1_015277 Cc1cc(C)c(C)c(OCC(=O)NCc2cccnc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P22 compound treatment 945003.0 10300.0 0.06 753197.0 21900.0 0.12 0.1272 0.9365 3625794 CBKinase1_015278 COc1ccccc1NC(=O)c2ccccc2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P23 compound treatment 1023984.0 89300.0 0.49 785534.0 54300.0 0.31 0.561 0.9748 3625795 CBKinase1_015279 [O-][N+](=O)c1ccccc1CC(=O)Nc2ccc3OCCOc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2371 P24 compound treatment 939567.0 4870.0 0.03 734623.0 3360.0 0.02 0.0322 0.9862 3625796 CBKinase1_015280 [O-][N+](=O)c1cccc(COC(=O)CN2C(=O)c3ccccc3C2=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A01 compound treatment 983567.0 60900.0 0.33 584088.0 -108000.0 -0.61 -0.1943 -0.2808 3625797 CBKinase1_015281 COc1ccc(Cl)cc1NC(=O)CCCN2C(=O)c3ccccc3C2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A02 compound treatment 877089.0 -45600.0 -0.25 543696.0 -148000.0 -0.83 -0.7664 -0.8798 1244160 CBKinase1_015282 COc1cccc(NC(=O)Cn2cnc3ccccc3c2=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A03 compound treatment 1067647.0 145000.0 0.79 504203.0 -188000.0 -1.06 -0.1881 -0.1425 3625798 CBKinase1_015283 CN(C)C(=O)c1ccc(NC(=O)Cn2nc(C)c3ccccc3c2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A04 compound treatment 873062.0 -49700.0 -0.27 665021.0 -26800.0 -0.15 -0.2984 -0.9617 3625799 CBKinase1_015284 Clc1cccc(NC(=O)CNS(=O)(=O)c2ccccc2)c1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A05 compound treatment 968094.0 45400.0 0.25 584784.0 -107000.0 -0.6 -0.2513 -0.3854 3625800 CBKinase1_015285 COc1cccc(Oc2coc3cc(OCC(=O)N)ccc3c2=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A06 compound treatment 1037947.0 115000.0 0.63 626556.0 -65200.0 -0.37 0.1849 0.2537 1863899 CBKinase1_015286 COc1cc(CNC2(CC3CC4(C)CC(C)(C3)C2)C4)cc(Br)c1OCC(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A07 compound treatment 893466.0 -29200.0 -0.16 571351.0 -120000.0 -0.68 -0.5929 -0.8502 3625801 CBKinase1_015287 Cc1nc(NS(=O)(=O)c2ccccc2)sc1NC(=O)Nc3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A08 compound treatment 902616.0 -20100.0 -0.11 611326.0 -80500.0 -0.45 -0.3983 -0.8536 1769035 CBKinase1_015288 COC(=O)c1ccc(NC(=O)CSc2nc(cc(=O)[nH]2)c3ccccc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A09 compound treatment 871844.0 -50900.0 -0.28 589239.0 -103000.0 -0.58 -0.6051 -0.9436 3625802 CBKinase1_015289 COc1ccc(Oc2ccc(NC(=O)CCC(=O)O)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A10 compound treatment 906588.0 -16100.0 -0.09 540422.0 -151000.0 -0.85 -0.6655 -0.776 3625803 CBKinase1_015290 Fc1ccc(NC(=O)Cn2cnc3scc(c4ccc(F)cc4)c3c2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A11 compound treatment 821010.0 -102000.0 -0.56 463845.0 -228000.0 -1.28 -1.3011 -0.9296 3625804 CBKinase1_015291 CC(C)c1ccc(NC(=O)CN(C)S(=O)(=O)c2ccccc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A12 compound treatment 927756.0 5040.0 0.03 687864.0 -3930.0 -0.02 0.0038 0.108 1984017 CBKinase1_015292 Brc1cnn(Cc2ccc(o2)C(=O)Nc3sc4CCCCCCc4c3C#N)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A13 mock treatment 3963889.0 3040000.0 16.6 669367.0 -22400.0 -0.13 11.651 0.7017 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A14 mock treatment 996878.0 74200.0 0.4 644149.0 -47600.0 -0.27 0.0964 0.1985 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A15 compound treatment 976832.0 54100.0 0.3 605390.0 -86400.0 -0.49 -0.1354 -0.2378 3625805 CBKinase1_015293 COC(=O)c1cc(OC)c(OC)cc1NC(=O)COc2ccc(OC)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A16 compound treatment 982849.0 60100.0 0.33 641825.0 -50000.0 -0.28 0.033 0.0763 3625806 CBKinase1_015294 COC(=O)c1ccc(COc2nc(C)cc(C)c2C#N)o1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A17 compound treatment 964631.0 41900.0 0.23 544687.0 -147000.0 -0.83 -0.4245 -0.4935 3625807 CBKinase1_015295 COc1ccc(C(Nc2cccc(C)n2)c3ccc4ccc(C)nc4c3O)c(OC)c1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A18 compound treatment 926655.0 3940.0 0.02 457088.0 -235000.0 -1.32 -0.9202 -0.6955 3625808 CBKinase1_015296 O=C(CSc1ccccn1)Nc2cccc3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A19 compound treatment 1086677.0 164000.0 0.9 520799.0 -171000.0 -0.96 -0.0485 -0.0369 3625809 CBKinase1_015297 Cc1ccc(cc1S(=O)(=O)N2CCOCC2)C(=O)Nc3ccccc3C(=O)N4CCCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A20 compound treatment 884791.0 -37900.0 -0.21 531968.0 -160000.0 -0.9 -0.7834 -0.8475 3625810 CBKinase1_015298 CC(C)c1ccc(OCC(=O)Nc2cc(ccc2N3CCOCC3)C(F)(F)F)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A21 compound treatment 708700.0 -214000.0 -1.17 470904.0 -221000.0 -1.24 -1.7065 -0.9995 3625811 CBKinase1_015299 OC(=O)CCSc1nnc2[nH]c3ccccc3n12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A22 compound treatment 691865.0 -231000.0 -1.26 512660.0 -179000.0 -1.01 -1.6051 -0.994 3625812 CBKinase1_015300 COc1ccc(NC(=O)COc2ccccc2)cc1NC(=O)c3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A23 compound treatment 718650.0 -204000.0 -1.11 696691.0 4900.0 0.03 -0.7682 -0.6894 3625813 CBKinase1_015301 Cc1sc2nc(SCC(=O)Nc3ccc(C)cc3)n(c4ccc(C)c(C)c4)c(=O)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 A24 compound treatment 767366.0 -155000.0 -0.85 649775.0 -42000.0 -0.24 -0.7672 -0.8712 3625814 CBKinase1_015302 Clc1ccc(NC(=O)CSc2nnc(o2)c3ccc(Br)cc3)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B01 compound treatment 977131.0 54400.0 0.3 583211.0 -109000.0 -0.61 -0.2227 -0.3273 3625815 CBKinase1_015303 Cc1ccnc(NC(c2ccc3ccc(C)nc3c2O)c4ccccc4[N+](=O)[O-])c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B02 compound treatment 975710.0 53000.0 0.29 611511.0 -80300.0 -0.45 -0.1154 -0.2148 3625816 CBKinase1_015304 CSc1ccc(cc1)C(Nc2cc(C)ccn2)c3ccc4ccc(C)nc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B03 compound treatment 1017522.0 94800.0 0.52 711620.0 19800.0 0.11 0.445 0.8404 3625817 CBKinase1_015305 CS(=O)(=O)N(CC(=O)Nc1cc(ccc1Cl)C(F)(F)F)c2ccc3OCCOc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B04 compound treatment 957363.0 34600.0 0.19 657071.0 -34700.0 -0.2 -0.0046 -0.017 3625818 CBKinase1_015306 COc1cc(C(c2c[nH]c3ccccc23)c4c[nH]c5ccccc45)c(O)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B05 compound treatment 1045520.0 123000.0 0.67 599605.0 -92200.0 -0.52 0.1067 0.1258 3625819 CBKinase1_015307 CC(=O)Nc1ccc(NC(=O)COc2ccccc2C(=O)Nc3cccc(Cl)c3Cl)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B06 compound treatment 1075352.0 153000.0 0.83 586631.0 -105000.0 -0.59 0.1701 0.1664 3625820 CBKinase1_015308 COc1ccc(cc1CSc2nc3cc(C)c(C)cc3[nH]2)C(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B07 compound treatment 933372.0 10700.0 0.06 755823.0 64000.0 0.36 0.2963 0.8106 3625821 CBKinase1_015309 Cc1ccc(NC(=O)CSc2nnc(c3cccs3)n2C)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B08 compound treatment 1000720.0 78000.0 0.43 690682.0 -1110.0 -0.01 0.2967 0.6967 3625822 CBKinase1_015310 Fc1ccccc1CSc2nnc(Cn3cnc4ccccc34)n2c5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B09 compound treatment 868562.0 -54200.0 -0.3 599166.0 -92600.0 -0.52 -0.5782 -0.9637 3625823 CBKinase1_015311 CCC(Oc1ccccc1)C(=O)Nc2cc3oc4ccccc4c3cc2OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B10 compound treatment 1053479.0 131000.0 0.71 611142.0 -80600.0 -0.45 0.1834 0.2167 3625824 CBKinase1_015312 [O-][N+](=O)c1ccc(NC(=O)CN2CCN(CC2)c3cccc(Cl)c3)c(c1)C(=O)Nc4ccccc4F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B11 compound treatment 901975.0 -20700.0 -0.11 607058.0 -84700.0 -0.48 -0.4178 -0.8512 3625825 CBKinase1_015313 Cn1c(SCC(=O)Nc2ccc(Cl)cc2Cl)nc3ccccc3c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B12 compound treatment 740380.0 -182000.0 -1.0 582173.0 -110000.0 -0.62 -1.1408 -0.9737 3625826 CBKinase1_015314 [O-][N+](=O)c1cccc(c1)C(=O)Nc2c(Cl)cc(Cl)cc2C(=O)NCCN3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B13 mock treatment 1030872.0 108000.0 0.59 634697.0 -57100.0 -0.32 0.19 0.2825 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B14 mock treatment 1031747.0 109000.0 0.6 527956.0 -164000.0 -0.92 -0.2321 -0.2112 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B15 compound treatment 919650.0 -3070.0 -0.02 567857.0 -124000.0 -0.7 -0.5058 -0.7238 3625827 CBKinase1_015315 Cc1ccc(NC(=O)CSc2nnc(o2)c3ccc(cc3)C(C)(C)C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B16 compound treatment 977785.0 55100.0 0.3 589999.0 -102000.0 -0.57 -0.1931 -0.2981 3625828 CBKinase1_015316 CCCc1cc(=O)[nH]c(SCC(=O)Nc2cc(Cl)ccc2Cl)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B17 compound treatment 1025978.0 103000.0 0.56 511072.0 -181000.0 -1.02 -0.3216 -0.2763 3625829 CBKinase1_015317 Clc1cccc(NC(=O)CSc2nc3ccccc3c(=O)n2c4cccc(Cl)c4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B18 compound treatment 912717.0 -10000.0 -0.05 736936.0 45100.0 0.25 0.1413 0.5431 3625830 CBKinase1_015318 Oc1ccc(Cc2ccc(NC(=O)c3ccccc3F)c(O)c2)cc1NC(=O)c4ccccc4F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B19 compound treatment 975584.0 52900.0 0.29 565595.0 -126000.0 -0.71 -0.2989 -0.3893 3625831 CBKinase1_015319 CC1CCCC(C)N1C(=O)c2ccccc2NC(=O)COc3ccccc3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B20 compound treatment 1054133.0 131000.0 0.72 600695.0 -91100.0 -0.51 0.1443 0.1635 3625832 CBKinase1_015320 COC(=O)c1ccc(NC(=O)CSc2nnc(C)n2c3ccccc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B21 compound treatment 1048292.0 126000.0 0.69 691427.0 -362.0 0.0 0.4833 0.705 3625833 CBKinase1_015321 COc1ccccc1n2c(SCC(=O)c3ccc4CCCCc4c3)nc5ccccc5c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B22 compound treatment 1016025.0 93300.0 0.51 685065.0 -6720.0 -0.04 0.3334 0.6527 3625834 CBKinase1_015322 Cc1c(NC(=O)c2nc[nH]n2)cccc1c3nc4cc(Cl)ccc4o3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B23 compound treatment 974629.0 51900.0 0.28 526167.0 -166000.0 -0.93 -0.4597 -0.4712 3625835 CBKinase1_015323 Cn1cc(C(c2cn(C)c3ccccc23)c4ccc(O)c(O)c4O)c5ccccc15 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 B24 compound treatment 959679.0 37000.0 0.2 671514.0 -20300.0 -0.11 0.0619 0.2669 3625836 CBKinase1_015324 Cc1ccc(C)c(c1)N2CCN(CC(=O)Nc3ccc(cc3C(=O)Nc4ccccc4F)[N+](=O)[O-])CC2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C01 compound treatment 1107611.0 185000.0 1.01 473352.0 -218000.0 -1.23 -0.1568 -0.0985 3625837 CBKinase1_015325 OCCSCC(=O)Nc1ccc(F)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C02 compound treatment 1014260.0 91500.0 0.5 581520.0 -110000.0 -0.62 -0.0861 -0.1079 3625838 CBKinase1_015326 CCc1cccc(OCC(=O)Nc2ccc(OC)cc2[N+](=O)[O-])c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C03 compound treatment 989057.0 66300.0 0.36 656959.0 -34800.0 -0.2 0.1173 0.2847 3625839 CBKinase1_015327 COC(=O)c1cccc(NC(=O)CSc2nc(=O)cc(N)n2c3ccccc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C04 compound treatment 905268.0 -17400.0 -0.1 491305.0 -200000.0 -1.13 -0.8664 -0.764 3625840 CBKinase1_015328 Fc1ccccc1NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C05 compound treatment 1098979.0 176000.0 0.96 550319.0 -141000.0 -0.8 0.1166 0.0933 3625841 CBKinase1_015329 Cc1ccc2n(CC(O)CN3CCOCC3)c4C(=O)CCCc4c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C06 compound treatment 959054.0 36300.0 0.2 607001.0 -84800.0 -0.48 -0.1976 -0.382 3625842 CBKinase1_015330 CS(=O)(=O)N(CC(=O)Nc1cccc(F)c1)Cc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C07 compound treatment 1044881.0 122000.0 0.67 707912.0 16100.0 0.09 0.5359 0.7961 3625843 CBKinase1_015331 COc1ccc(NC(=O)CSc2nnc3sc4ccccc4n23)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C08 compound treatment 1017731.0 95000.0 0.52 684471.0 -7320.0 -0.04 0.3376 0.6488 3625844 CBKinase1_015332 COc1ccc(OC)c(NC(=O)CSc2nnc(c3ccccc3)n2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C09 compound treatment 1065798.0 143000.0 0.78 575346.0 -116000.0 -0.66 0.0883 0.0865 3625845 CBKinase1_015333 [O-][N+](=O)c1ccc(CSc2nnc3c4ccccc4n(CC=C)c3n2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C10 compound treatment 951113.0 28400.0 0.16 646763.0 -45000.0 -0.25 -0.0698 -0.2348 3625846 CBKinase1_015334 O=C(Nc1ccccc1C(=O)NCC2CCCO2)c3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C11 mock treatment 938018.0 15300.0 0.08 636892.0 -54900.0 -0.31 -0.1597 -0.4983 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C12 mock treatment 1065573.0 143000.0 0.78 683878.0 -7910.0 -0.04 0.52 0.6656 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C13 compound treatment 992928.0 70200.0 0.38 683851.0 -7940.0 -0.04 0.2394 0.6204 3625847 CBKinase1_015335 CCOc1ccc(cc1)C(Nc2cccc(C)n2)c3ccc4ccc(C)nc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C14 compound treatment 950735.0 28000.0 0.15 578061.0 -114000.0 -0.64 -0.3451 -0.5237 1294297 CBKinase1_015336 COc1cccc(NC(=O)Cn2c(=O)oc3ccccc23)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C15 mock treatment 976898.0 54200.0 0.3 579155.0 -113000.0 -0.63 -0.2397 -0.3423 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C16 mock treatment 1001899.0 79200.0 0.43 635701.0 -56100.0 -0.32 0.0821 0.1534 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C17 compound treatment 381573.0 -541000.0 -2.95 446677.0 -245000.0 -1.38 -3.066 -0.9401 3625848 CBKinase1_015337 [O-][N+](=O)c1ccccc1C(c2c[nH]c3ccccc23)c4c[nH]c5ccccc45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C18 compound treatment 961297.0 38600.0 0.21 775871.0 84100.0 0.47 0.4841 0.9333 3625849 CBKinase1_015338 Cc1nn(Cc2cccc(c2)C(=O)NCc3ccccn3)c(C)c1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C19 compound treatment 623717.0 -299000.0 -1.63 646290.0 -45500.0 -0.26 -1.3356 -0.8083 3625850 CBKinase1_015339 Cc1cccc(NC(c2ccccc2C)c3ccc4ccc(C)nc4c3O)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C20 compound treatment 896619.0 -26100.0 -0.14 679579.0 -12200.0 -0.07 -0.1494 -0.9443 3625851 CBKinase1_015340 Brc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)Nc4ccccc4)sc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C21 compound treatment 1002068.0 79400.0 0.43 469584.0 -222000.0 -1.25 -0.5793 -0.4371 3625852 CBKinase1_015341 CCn1nccc1C(=O)Nc2nc3ccccc3n2CCN4CCCCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C22 compound treatment 938116.0 15400.0 0.08 525078.0 -167000.0 -0.94 -0.605 -0.6413 3625853 CBKinase1_015342 CCn1c(SCC(=O)Nc2ccccc2OC)nnc1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C23 compound treatment 747137.0 -176000.0 -0.96 499896.0 -192000.0 -1.08 -1.4426 -0.9982 3625854 CBKinase1_015343 COC(=O)c1ccc(NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 C24 compound treatment 851910.0 -70800.0 -0.39 544490.0 -147000.0 -0.83 -0.8604 -0.9395 3625855 CBKinase1_015344 Clc1cc(Cl)c2oc(=O)c(cc2c1)C(=O)NCc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D01 compound treatment 1012911.0 90200.0 0.49 345419.0 -346000.0 -1.95 -1.0323 -0.5127 3625856 CBKinase1_015345 COc1cccc(c1)c2nnc(SCC(=O)Nc3cccc(Cl)c3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D02 compound treatment 823760.0 -99000.0 -0.54 536063.0 -156000.0 -0.88 -1.0027 -0.9728 3625857 CBKinase1_015346 Cc1ccnc(NC(c2cccc(c2)[N+](=O)[O-])c3ccc4ccc(C)nc4c3O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D03 compound treatment 967319.0 44600.0 0.24 652019.0 -39800.0 -0.22 0.0137 0.0413 3625858 CBKinase1_015347 CCCCN1C(=O)C(O)(CC(=O)c2ccccn2)c3ccccc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D04 compound treatment 988451.0 65700.0 0.36 656806.0 -35000.0 -0.2 0.1143 0.2792 3625859 CBKinase1_015348 COC(=O)c1ccc(OCC(=O)Nc2cc(OC)ccc2OC)c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D05 compound treatment 972425.0 49700.0 0.27 653484.0 -38300.0 -0.22 0.0392 0.1131 3625860 CBKinase1_015349 NS(=O)(=O)c1ccc(NC(=O)CC2c3ccccc3Oc4ccccc24)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D06 compound treatment 988474.0 65800.0 0.36 555093.0 -137000.0 -0.77 -0.291 -0.3423 3625861 CBKinase1_015350 CC(C)C(=O)Nc1ccccc1C(=O)OCc2cccc(c2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D07 compound treatment 954717.0 32000.0 0.17 659709.0 -32100.0 -0.18 -0.0043 -0.0172 3625862 CBKinase1_015351 Cn1c(SCC(=O)Nc2ccc(Cl)cc2Cl)nnc1C3(CC4CC5CC(C4)C3)C5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D08 compound treatment 975514.0 52800.0 0.29 684964.0 -6830.0 -0.04 0.1766 0.6074 3625863 CBKinase1_015352 OC1(CC(=O)c2ccccn2)C(=O)Nc3ccc(I)cc31 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D09 compound treatment 990153.0 67400.0 0.37 523221.0 -169000.0 -0.95 -0.4115 -0.4038 3625864 CBKinase1_015353 CCC(=O)Nc1ccc(Cl)c(NC(=O)COc2ccc(Br)cc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D10 compound treatment 904104.0 -18600.0 -0.1 517453.0 -174000.0 -0.98 -0.7667 -0.7761 3625865 CBKinase1_015354 Cn1c(SCC(=O)N2c3ccccc3CCc4ccccc24)nnc1c5ccc(Cl)cc5Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D11 mock treatment 984569.0 61900.0 0.34 704161.0 12400.0 0.07 0.2881 0.8355 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D12 mock treatment 942746.0 20000.0 0.11 715555.0 23800.0 0.13 0.172 0.9949 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D13 compound treatment 1009264.0 86500.0 0.47 548835.0 -143000.0 -0.81 -0.2356 -0.2523 3625866 CBKinase1_015355 Cc1ccc(OCC(=O)Nc2ccc3c(c2)oc4ccccc43)cc1[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D14 compound treatment 1029663.0 107000.0 0.58 750067.0 58300.0 0.33 0.6451 0.963 3625867 CBKinase1_015356 CC(C)c1ccc(NC(=O)CSc2nnc(c3ccccc3O)n2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D15 mock treatment 976864.0 54100.0 0.3 592502.0 -99300.0 -0.56 -0.1867 -0.2949 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D16 mock treatment 887436.0 -35300.0 -0.19 781194.0 89400.0 0.5 0.2201 0.408 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D17 compound treatment 994498.0 71800.0 0.39 667933.0 -23900.0 -0.13 0.182 0.4394 3625868 CBKinase1_015357 COc1ccccc1NC(=O)c2ccccc2NC(=O)COc3ccccc3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D18 compound treatment 965358.0 42600.0 0.23 587860.0 -104000.0 -0.59 -0.2496 -0.396 3625869 CBKinase1_015358 Cc1nnc(SCC(=O)Nc2cc(Cl)ccc2C)s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D19 compound treatment 527428.0 -395000.0 -2.16 599778.0 -92000.0 -0.52 -1.8927 -0.8528 3625870 CBKinase1_015359 Cc1ccnc(NC(c2cccc(Br)c2)c3ccc4ccc(C)nc4c3O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D20 compound treatment 928974.0 6260.0 0.03 574536.0 -117000.0 -0.66 -0.4432 -0.6697 3625871 CBKinase1_015360 Cc1ccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccccc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D21 compound treatment 899660.0 -23100.0 -0.13 521155.0 -171000.0 -0.96 -0.7691 -0.7929 1773643 CBKinase1_015361 Cn1nc(CC(=O)Nc2ccc3c(c2)oc4ccccc43)c5ccccc5c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D22 compound treatment 983988.0 61300.0 0.33 560973.0 -131000.0 -0.74 -0.2848 -0.3518 1505627 CBKinase1_015362 COc1ccc(cc1)c2nc(C#N)c(NCCN3CCOCC3)o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D23 compound treatment 715993.0 -207000.0 -1.13 553990.0 -138000.0 -0.78 -1.3472 -0.9834 3625872 CBKinase1_015363 [O-][N+](=O)c1cccc(c1)C(=O)Nc2c(Cl)cc(Cl)cc2C(=O)NCc3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 D24 compound treatment 873433.0 -49300.0 -0.27 530661.0 -161000.0 -0.91 -0.8324 -0.8788 3625873 CBKinase1_015364 COc1cccc(c1)c2cc(C(=O)NCc3ccco3)c4cc(C)cc(C)c4n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E01 mock treatment 904123.0 -18600.0 -0.1 741221.0 49400.0 0.28 0.1252 0.4223 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E02 mock treatment 733677.0 -189000.0 -1.03 653112.0 -38700.0 -0.22 -0.8839 -0.838 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E03 compound treatment 816595.0 -106000.0 -0.58 652326.0 -39500.0 -0.22 -0.567 -0.9136 1983966 CBKinase1_015365 COc1ccccc1NC(=O)CSC2=NC(=O)CC(N2)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E04 compound treatment 850940.0 -71800.0 -0.39 624803.0 -67000.0 -0.38 -0.5441 -0.9998 3625874 CBKinase1_015366 Cc1ccc(OCC(=O)N(C2CCCCC2)c3ccccn3)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E05 compound treatment 839036.0 -83700.0 -0.46 675094.0 -16700.0 -0.09 -0.3896 -0.8352 3625875 CBKinase1_015367 Clc1cccc(Cl)c1NC(=O)CSc2nnc3sc4ccccc4n23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E06 compound treatment 788133.0 -135000.0 -0.73 697708.0 5920.0 0.03 -0.496 -0.6743 3625876 CBKinase1_015368 Cn1c(SCC(=O)c2ccc(Cl)cc2Cl)nnc1c3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E07 compound treatment 909354.0 -13400.0 -0.07 698724.0 6930.0 0.04 -0.0239 -0.2893 3625877 CBKinase1_015369 Cc1ccccc1NC(=O)CSCCO 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E08 compound treatment 760284.0 -162000.0 -0.89 618148.0 -73600.0 -0.42 -0.9206 -0.9402 3625878 CBKinase1_015370 CC(=O)c1ccccc1OC(=O)CCN2C(=O)C3C(C4c5ccccc5C3c6ccccc46)C2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E09 mock treatment 844017.0 -78700.0 -0.43 657686.0 -34100.0 -0.19 -0.4397 -0.9342 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E10 mock treatment 814992.0 -108000.0 -0.59 679030.0 -12800.0 -0.07 -0.4667 -0.7877 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E11 compound treatment 878061.0 -44700.0 -0.24 744319.0 52500.0 0.3 0.037 0.0964 3625879 CBKinase1_015371 Cc1cc(NC(=O)CSc2nnc(c3ccccc3Cl)n2C)ccc1Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E12 compound treatment 777418.0 -145000.0 -0.79 689494.0 -2300.0 -0.01 -0.5701 -0.7185 3625880 CBKinase1_015372 Cc1c(Cl)cccc1NC(=O)CN2CCN(CCO)CC2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E13 compound treatment 929754.0 7040.0 0.04 709605.0 17800.0 0.1 0.0982 0.9131 3625881 CBKinase1_015373 Oc1cc(ccc1NC(=O)COc2ccc(I)cc2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E14 compound treatment 907100.0 -15600.0 -0.09 682507.0 -9280.0 -0.05 -0.0973 -0.9725 3625882 CBKinase1_015374 OC(=O)CCN1C(=O)c2ccc(NC(=O)c3ccco3)cc2C1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E15 compound treatment 892791.0 -29900.0 -0.16 647232.0 -44600.0 -0.25 -0.2931 -0.9783 3625883 CBKinase1_015375 O=C(CN1C(=O)c2ccccc2C1=O)Nc3ccc(NC(=O)c4ccco4)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E16 compound treatment 933639.0 10900.0 0.06 695867.0 4080.0 0.02 0.0584 0.9141 3625884 CBKinase1_015376 Brc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc4ccccc34)o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E17 mock treatment 856651.0 -66100.0 -0.36 679017.0 -12800.0 -0.07 -0.3059 -0.8318 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E18 mock treatment 828103.0 -94600.0 -0.52 674853.0 -16900.0 -0.1 -0.4327 -0.8238 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E19 compound treatment 704108.0 -219000.0 -1.19 693323.0 1530.0 0.01 -0.8378 -0.702 3625885 CBKinase1_015377 OC(=O)C1CCCN1S(=O)(=O)c2cc(ccc2Cl)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E20 compound treatment 855477.0 -67200.0 -0.37 627960.0 -63800.0 -0.36 -0.514 -0.9999 3625886 CBKinase1_015378 NC(=O)CSc1nnc(c2cccs2)n1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E21 compound treatment 657333.0 -265000.0 -1.45 672702.0 -19100.0 -0.11 -1.1006 -0.7575 3625887 CBKinase1_015379 CC1=C(C(C(=C(N1)SCC(=O)c2ccc(C)cc2)C#N)c3ccco3)C(=O)Nc4ccccc4F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E22 compound treatment 727727.0 -195000.0 -1.06 715669.0 23900.0 0.13 -0.6576 -0.6128 3625888 CBKinase1_015380 NC(=O)c1c(NC(=O)C(Cc2ccccc2)N3C(=O)c4ccccc4C3=O)sc5CCCCc15 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E23 compound treatment 622141.0 -301000.0 -1.64 623341.0 -68400.0 -0.39 -1.4332 -0.8502 3625889 CBKinase1_015381 COc1ccc(OC(=O)CCN2C(=O)C3C4CC(C=C4)C3C2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 E24 compound treatment 718998.0 -204000.0 -1.11 552708.0 -139000.0 -0.78 -1.3408 -0.9853 3625890 CBKinase1_015382 CCC(Sc1nc(N)cc(=O)[nH]1)C(=O)Nc2ccc3ccccc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F01 mock treatment 779383.0 -143000.0 -0.78 626135.0 -65700.0 -0.37 -0.815 -0.9415 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F02 mock treatment 832592.0 -90100.0 -0.49 623418.0 -68400.0 -0.39 -0.6204 -0.9927 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F03 compound treatment 920598.0 -2120.0 -0.01 624237.0 -67600.0 -0.38 -0.2774 -0.7282 3625891 CBKinase1_015383 Cc1ccnc(NC(c2ccc3ccc(C)nc3c2O)c4cc(C)ccc4C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F04 compound treatment 747669.0 -175000.0 -0.96 519114.0 -173000.0 -0.97 -1.364 -1.0 3625892 CBKinase1_015384 COc1ccc(NC(=O)CSc2nc3ccccc3n2c4ccccc4)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F05 compound treatment 890238.0 -32500.0 -0.18 641873.0 -49900.0 -0.28 -0.3243 -0.9752 3625893 CBKinase1_015385 Cc1cc(C)c2nc(cc(C(=O)NCc3ccco3)c2c1)c4ccc(F)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F06 compound treatment 884817.0 -37900.0 -0.21 589056.0 -103000.0 -0.58 -0.5558 -0.9038 3625894 CBKinase1_015386 COc1ccccc1N2CCN(CC(=O)Nc3ccc(cc3C(=O)Nc4ccccc4F)[N+](=O)[O-])CC2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F07 compound treatment 744703.0 -178000.0 -0.97 567946.0 -124000.0 -0.7 -1.1808 -0.9868 3625895 CBKinase1_015387 O=C(CSc1nnc(o1)c2ccco2)N3c4ccccc4CCc5ccccc35 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F08 compound treatment 969352.0 46600.0 0.25 609652.0 -82100.0 -0.46 -0.1473 -0.2788 3625896 CBKinase1_015388 COc1ccc(NC(=O)CCn2cnc3ccccc3c2=O)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F09 mock treatment 885948.0 -36800.0 -0.2 671025.0 -20800.0 -0.12 -0.2247 -0.967 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F10 mock treatment 913596.0 -9120.0 -0.05 711503.0 19700.0 0.11 0.0434 0.3562 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F11 compound treatment 931943.0 9230.0 0.05 654291.0 -37500.0 -0.21 -0.1138 -0.5239 3625897 CBKinase1_015389 CCc1cccc(C)c1NC(=O)CSc2nc3cc(C)cc(n4nc5ccccc5n4)c3o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F12 compound treatment 831137.0 -91600.0 -0.5 573927.0 -118000.0 -0.66 -0.8233 -0.9902 3625898 CBKinase1_015390 Cc1c(Cl)cccc1NC(=O)CSc2nc(cs2)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F13 compound treatment 868757.0 -54000.0 -0.29 532440.0 -159000.0 -0.9 -0.8434 -0.8923 3625899 CBKinase1_015391 O=C(CSc1nc(cs1)c2ccccc2)Nc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F14 compound treatment 937057.0 14300.0 0.08 635364.0 -56400.0 -0.32 -0.1695 -0.5176 3625900 CBKinase1_015392 Cc1cc(Cl)ccc1NC(=O)CSc2nnc(c3cccs3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F15 compound treatment 942244.0 19500.0 0.11 577225.0 -115000.0 -0.65 -0.3812 -0.5825 3625901 CBKinase1_015393 CCC(=O)Nc1ccc(Cl)c(NC(=O)COc2cc(C)cc(C)c2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F16 compound treatment 882379.0 -40300.0 -0.22 627192.0 -64600.0 -0.36 -0.4132 -0.971 3625902 CBKinase1_015394 COc1cc(NC(=S)NCCCO)c(OC)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F17 mock treatment 864114.0 -58600.0 -0.32 672315.0 -19500.0 -0.11 -0.3038 -0.8983 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F18 mock treatment 922885.0 170.0 0.0 653978.0 -37800.0 -0.21 -0.15 -0.704 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F19 compound treatment 664959.0 -258000.0 -1.41 555522.0 -136000.0 -0.77 -1.5382 -0.9594 3625903 CBKinase1_015395 Cc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2c4cccc(c4)C(F)(F)F)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F20 compound treatment 696023.0 -227000.0 -1.24 585291.0 -106000.0 -0.6 -1.2996 -0.9448 3625904 CBKinase1_015396 COc1ccc(NC(=O)CS(=O)(=O)c2ccc(C)cc2)c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F21 compound treatment 1138585.0 216000.0 1.18 207170.0 -485000.0 -2.73 -1.0981 -0.3691 3625905 CBKinase1_015397 COc1cccc(NC(=O)c2cc(ccc2NC(=O)CN3CCc4ccccc4C3)[N+](=O)[O-])c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F22 compound treatment 738304.0 -184000.0 -1.01 618645.0 -73100.0 -0.41 -1.0034 -0.9223 1579907 CBKinase1_015398 Cc1cc(C)n(n1)C(=O)c2ccc(COc3c(F)c(F)cc(F)c3F)o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F23 compound treatment 610570.0 -312000.0 -1.7 578336.0 -113000.0 -0.64 -1.6572 -0.9105 3625906 CBKinase1_015399 Cc1c(Cl)cccc1NC(=O)c2ccccc2OCC(=O)Nc3ccc4CCc5cccc3c54 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 F24 compound treatment 744639.0 -178000.0 -0.97 525321.0 -166000.0 -0.94 -1.3509 -0.9998 3625907 CBKinase1_015400 Cc1cc2c(NC(=O)C2(O)CC(=O)c3ccccn3)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G01 compound treatment 921606.0 -1110.0 -0.01 731112.0 39300.0 0.22 0.1524 0.6875 3625908 CBKinase1_015401 CC(C)C(N1C(=O)c2ccccc2C1=O)C(=O)Nc3ccc(cc3)S(=O)(=O)N4CCOCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G02 compound treatment 949542.0 26800.0 0.15 766726.0 74900.0 0.42 0.4022 0.8997 3625909 CBKinase1_015402 CCn1c(SCC(=O)Nc2ccc(Cl)cc2Cl)nnc1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G03 mock treatment 881742.0 -41000.0 -0.22 767213.0 75400.0 0.43 0.1424 0.2965 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G04 mock treatment 914080.0 -8640.0 -0.05 790972.0 99200.0 0.56 0.362 0.6452 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G05 compound treatment 881836.0 -40900.0 -0.22 796785.0 105000.0 0.59 0.2607 0.4121 3625910 CBKinase1_015403 OC(=O)CCCNC(=O)c1cccnc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G06 compound treatment 883478.0 -39200.0 -0.21 775116.0 83300.0 0.47 0.1806 0.3499 3625911 CBKinase1_015404 CN(CC(=O)Nc1c(F)cccc1F)S(=O)(=O)c2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G07 compound treatment 890085.0 -32600.0 -0.18 823527.0 132000.0 0.74 0.3991 0.5226 1282664 CBKinase1_015405 Cc1ccc(c(C)c1)S(=O)(=O)N(C(=O)c2ccncc2)c3ccc(OC(=O)c4ccncc4)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G08 compound treatment 903793.0 -18900.0 -0.1 960537.0 269000.0 1.51 0.9981 0.6574 3625912 CBKinase1_015406 COc1ccc(cc1)C(=O)Nc2ccccc2C(=O)NCc3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G09 compound treatment 893519.0 -29200.0 -0.16 880515.0 189000.0 1.06 0.6395 0.5945 1653761 CBKinase1_015407 CCNc1nc(NC(C)(C)C)nc(n1)N(CC(=O)OC)C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G10 compound treatment 898239.0 -24500.0 -0.13 892200.0 200000.0 1.13 0.7043 0.6191 1692921 CBKinase1_015408 COc1cc(cc(OC)c1OC)c2nnc(SCC(=O)N)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G11 compound treatment 888678.0 -34000.0 -0.19 800691.0 109000.0 0.61 0.3026 0.4719 3625913 CBKinase1_015409 CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3ccc(cc3)S(=O)(=O)N4CC(C)OC(C)C4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G12 compound treatment 895327.0 -27400.0 -0.15 837315.0 146000.0 0.82 0.4743 0.5688 3625914 CBKinase1_015410 Cc1c(Cl)cccc1NC(=O)CSc2nnc(c3ccc(cc3)[N+](=O)[O-])n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G13 compound treatment 939263.0 16500.0 0.09 835054.0 143000.0 0.81 0.6349 0.7813 3625915 CBKinase1_015411 COC(=O)c1cc(OC)c(OC)cc1NC(=O)COc2ccc(Cl)cc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G14 compound treatment 941011.0 18300.0 0.1 822691.0 131000.0 0.74 0.5923 0.7956 3625916 CBKinase1_015412 CCc1ccc(NC(=O)CSc2nc(cc(=O)[nH]2)c3ccc(OC)cc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G15 compound treatment 913966.0 -8750.0 -0.05 863599.0 172000.0 0.97 0.651 0.6714 3625917 CBKinase1_015413 CN(CC(=O)O)C(=O)c1ccc(cc1)S(=O)(=O)N2CCCC2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G16 compound treatment 898322.0 -24400.0 -0.13 831452.0 140000.0 0.79 0.4625 0.5792 3625918 CBKinase1_015414 COCc1cc(ccc1OC)C2SCC(=O)Nc3c2c(C)nn3c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G17 compound treatment 849054.0 -73700.0 -0.4 879631.0 188000.0 1.06 0.4643 0.4099 3625919 CBKinase1_015415 Oc1ccc(cc1C(c2c[nH]c3ccccc23)c4c[nH]c5ccccc45)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G18 compound treatment 845803.0 -76900.0 -0.42 800251.0 108000.0 0.61 0.1354 0.1825 3625920 CBKinase1_015416 CCC(Sc1nnc(c2ccccc2)n1c3ccccc3)C(=O)Nc4ccc(Cl)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G19 mock treatment 801731.0 -121000.0 -0.66 754511.0 62700.0 0.35 -0.2171 -0.2898 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G20 mock treatment 772994.0 -150000.0 -0.82 755536.0 63700.0 0.36 -0.3239 -0.3628 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G21 compound treatment 782578.0 -140000.0 -0.77 788890.0 97100.0 0.55 -0.154 -0.1637 3625921 CBKinase1_015417 Cc1ccc(C)c(NC(=O)CSc2nnc(c3ccc(N)cc3)n2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G22 compound treatment 782549.0 -140000.0 -0.77 719689.0 27900.0 0.16 -0.4299 -0.5503 3625922 CBKinase1_015418 Fc1cccc(F)c1NC(=O)CN(C2CCCCC2)S(=O)(=O)c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G23 compound treatment 785337.0 -137000.0 -0.75 713023.0 21200.0 0.12 -0.4457 -0.5868 1567416 CBKinase1_015419 COc1ccc2oc(=O)c(cc2c1)C(=O)NCc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 G24 compound treatment 746618.0 -176000.0 -0.96 538490.0 -153000.0 -0.86 -1.2908 -0.9986 3625923 CBKinase1_015420 COC(=O)c1c(NC(=O)c2ccc(Cn3cc(Cl)cn3)cc2)sc4CCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H01 compound treatment 876873.0 -45800.0 -0.25 788555.0 96800.0 0.55 0.2087 0.3478 3625924 CBKinase1_015421 Nc1nncn1C(=O)CCCOc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H02 compound treatment 943791.0 21100.0 0.12 768777.0 77000.0 0.43 0.3882 0.8647 3625925 CBKinase1_015422 [O-][N+](=O)c1cccc(c1)C(=O)Nc2ccccc2C(=O)NCCN3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H03 mock treatment 941562.0 18800.0 0.1 799821.0 108000.0 0.61 0.5033 0.815 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H04 mock treatment 944223.0 21500.0 0.12 829796.0 138000.0 0.78 0.6331 0.8047 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H05 compound treatment 924509.0 1790.0 0.01 790853.0 99100.0 0.56 0.4017 0.7194 3625926 CBKinase1_015423 COc1cc(NC(=O)COc2ccc(C)c(C)c2)ccc1NC(=O)c3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H06 compound treatment 943556.0 20800.0 0.11 791821.0 100000.0 0.56 0.4791 0.833 3625927 CBKinase1_015424 OCCN1CCN(CC1)C(=O)c2ccccc2NC(=O)c3cccc(c3)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H07 compound treatment 944621.0 21900.0 0.12 811241.0 119000.0 0.67 0.5606 0.8199 3625928 CBKinase1_015425 Cc1cccc(NC(=O)CSc2nnc(c3cccnc3)n2c4ccccc4)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H08 compound treatment 950681.0 28000.0 0.15 852546.0 161000.0 0.91 0.7487 0.8148 3625929 CBKinase1_015426 COc1ccc(cc1OC)c2nnc(SCC(=O)Nc3ccc(C)cc3C)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H09 compound treatment 942953.0 20200.0 0.11 810920.0 119000.0 0.67 0.5529 0.8125 3625930 CBKinase1_015427 CS(=O)(=O)N(CC(=O)Nc1ccc(I)cc1)c2ccc3OCCOc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H10 compound treatment 961239.0 38500.0 0.21 867121.0 175000.0 0.99 0.8475 0.8388 3625931 CBKinase1_015428 COc1ccccc1OCC(=O)Nc2cccc(c2)C(=O)N3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H11 compound treatment 900689.0 -22000.0 -0.12 827632.0 136000.0 0.77 0.4564 0.5888 3625932 CBKinase1_015429 Cc1c(NC(=O)CN(c2ccc3OCCOc3c2)S(=O)(=O)C)c(=O)n(c4ccccc4)n1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H12 compound treatment 900685.0 -22000.0 -0.12 852108.0 160000.0 0.9 0.5539 0.6076 3625933 CBKinase1_015430 CCc1ccccc1NC(=O)CSc2nnc(c3cc4ccccc4cc3O)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H13 compound treatment 971475.0 48800.0 0.27 850950.0 159000.0 0.9 0.8226 0.879 3625934 CBKinase1_015431 O=C(NCCc1c[nH]c2ccccc12)NC3CCCCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H14 compound treatment 922313.0 -402.0 0.0 877173.0 185000.0 1.04 0.7373 0.7056 3625935 CBKinase1_015432 O=S(=O)(NCc1cccnc1)c2ccc(cc2)C3CCCCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H15 compound treatment 939013.0 16300.0 0.09 847866.0 156000.0 0.88 0.685 0.7747 1121936 CBKinase1_015433 Cc1ccc(o1)C(=O)CC2(O)C(=O)Nc3ccccc32 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H16 compound treatment 956131.0 33400.0 0.18 852904.0 161000.0 0.91 0.7711 0.8325 3625936 CBKinase1_015434 CCc1cccc(C)c1NC(=O)CN(C)S(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H17 compound treatment 998360.0 75600.0 0.41 879483.0 188000.0 1.06 1.0401 0.9158 3625937 CBKinase1_015435 CCOc1c(O)ccc(C(c2c[nH]c3ccccc23)c4c[nH]c5ccccc45)c1[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H18 compound treatment 944882.0 22200.0 0.12 843889.0 152000.0 0.86 0.6918 0.799 3625938 CBKinase1_015436 Cc1cc(C)c(C)c(c1C)S(=O)(=O)NCc2cccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H19 mock treatment 959201.0 36500.0 0.2 764667.0 72900.0 0.41 0.4313 0.9448 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H20 mock treatment 895497.0 -27200.0 -0.15 778147.0 86400.0 0.49 0.2391 0.4698 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H21 compound treatment 838761.0 -84000.0 -0.46 759083.0 67300.0 0.38 -0.0559 -0.094 3625939 CBKinase1_015437 Clc1cccc(NC(=O)CSc2nc3ccc(cc3[nH]2)C(=O)c4ccccc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H22 compound treatment 842994.0 -79700.0 -0.44 757342.0 65600.0 0.37 -0.0465 -0.0814 3625940 CBKinase1_015438 Cc1ccc(OCC(=O)Nc2cc(ccc2N3CCOCC3)C(F)(F)F)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H23 compound treatment 900158.0 -22600.0 -0.12 765858.0 74100.0 0.42 0.2081 0.4781 3625941 CBKinase1_015439 Cc1ccccc1NC(=O)COc2ccc(C)c(c2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 H24 compound treatment 862462.0 -60300.0 -0.33 727631.0 35800.0 0.2 -0.0898 -0.2325 3625942 CBKinase1_015440 COc1ccc(OC)c(NC(=O)CSc2nnnn2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I01 compound treatment 979831.0 57100.0 0.31 484853.0 -207000.0 -1.17 -0.6043 -0.5005 1848008 CBKinase1_015441 COc1ccccc1NC(=O)CSC2=NCCS2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I02 compound treatment 1054747.0 132000.0 0.72 605537.0 -86300.0 -0.49 0.1659 0.1909 3625943 CBKinase1_015442 Cc1nnc(SCC(=O)Nc2cccc(c2)[N+](=O)[O-])s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I03 compound treatment 1035142.0 112000.0 0.61 607789.0 -84000.0 -0.47 0.0992 0.128 3625944 CBKinase1_015443 CC1CCc2c(C1)sc3nc(SCC(=O)NCC4CCCO4)n(c5ccccc5)c(=O)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I04 compound treatment 1050633.0 128000.0 0.7 643884.0 -47900.0 -0.27 0.3029 0.4045 3625945 CBKinase1_015444 CCOC(=O)c1ccc(NC(=O)Cn2cnc3ccccc3c2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I05 mock treatment 1119060.0 196000.0 1.07 634778.0 -57000.0 -0.32 0.5308 0.4743 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I06 mock treatment 1051373.0 129000.0 0.7 673515.0 -18300.0 -0.1 0.4238 0.597 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I07 compound treatment 1089300.0 167000.0 0.91 676426.0 -15400.0 -0.09 0.5819 0.6369 3625946 CBKinase1_015445 CCOc1ccc2[nH]c(SCC(=O)Nc3c(C)cccc3C)nc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I08 compound treatment 1113535.0 191000.0 1.04 707510.0 15700.0 0.09 0.7993 0.7645 3625947 CBKinase1_015446 CCn1c(SCC(=O)Nc2ccc(Br)cc2)nnc1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I09 compound treatment 915915.0 -6800.0 -0.04 694260.0 2470.0 0.01 -0.0164 -0.4137 3625948 CBKinase1_015447 CCn1c(SCC(=O)Nc2ccc(F)cc2)nnc1c3ccc(Cl)cc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I10 compound treatment 1065061.0 142000.0 0.78 674608.0 -17200.0 -0.1 0.481 0.6142 3625949 CBKinase1_015448 COc1cc(NC(=O)CSc2nc(C)cc(=O)[nH]2)c(OC)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I11 compound treatment 1080554.0 158000.0 0.86 671604.0 -20200.0 -0.11 0.5289 0.6085 3625950 CBKinase1_015449 O=C(CSc1nnc2ccc3ccccc3n12)Nc4ccc5OCCOc5c4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I12 compound treatment 975450.0 52700.0 0.29 630761.0 -61000.0 -0.34 -0.0397 -0.0884 3625951 CBKinase1_015450 Clc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)NCCN3CCOCC3)c(Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I13 compound treatment 1077709.0 155000.0 0.85 680244.0 -11500.0 -0.07 0.5523 0.6508 3625952 CBKinase1_015451 Cc1ccc(OCC(=O)Nc2ccc(Cl)cc2C(=O)O)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I14 compound treatment 930876.0 8160.0 0.04 706812.0 15000.0 0.08 0.0914 0.955 3625953 CBKinase1_015452 CCn1c(SCC(=O)Nc2ccccc2F)nnc1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I15 compound treatment 986231.0 63500.0 0.35 610930.0 -80900.0 -0.46 -0.0771 -0.1346 3625954 CBKinase1_015453 CC(C)Oc1ccc(cc1)C(Nc2cc(C)ccn2)c3ccc4cccnc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I16 compound treatment 1121118.0 198000.0 1.08 709793.0 18000.0 0.1 0.8377 0.77 3625955 CBKinase1_015454 COc1cc(NC(=O)C2CCCO2)c(cc1OC)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I17 compound treatment 1083499.0 161000.0 0.88 692732.0 943.0 0.01 0.6245 0.7114 3625956 CBKinase1_015455 Clc1ccc(NS(=O)(=O)c2cccc(c2)S(=O)(=O)c3ccccc3)nc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I18 compound treatment 826482.0 -96200.0 -0.53 655501.0 -36300.0 -0.2 -0.5161 -0.9155 3625957 CBKinase1_015456 Clc1ccc(C(=O)Nc2ccccc2C(=O)NCc3cccnc3)c(Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I19 compound treatment 992446.0 69700.0 0.38 803747.0 112000.0 0.63 0.7154 0.9707 3625958 CBKinase1_015457 COc1cc(OC)cc(c1)c2nnc(SCC(=O)Nc3ccc(Cl)cc3C)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I20 compound treatment 916055.0 -6660.0 -0.04 762606.0 70800.0 0.4 0.2565 0.64 3625959 CBKinase1_015458 COc1ccc(cc1CSc2nnc(c3ccccc3)n2c4ccccc4)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I21 mock treatment 757513.0 -165000.0 -0.9 708549.0 16800.0 0.09 -0.571 -0.6296 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I22 mock treatment 909884.0 -12800.0 -0.07 659178.0 -32600.0 -0.18 -0.1795 -0.9126 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I23 compound treatment 930464.0 7750.0 0.04 687106.0 -4680.0 -0.03 0.0112 0.2256 3625960 CBKinase1_015459 Cc1ccc(C)c(NC(=O)CNS(=O)(=O)c2ccccc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 I24 compound treatment 979036.0 56300.0 0.31 695617.0 3830.0 0.02 0.2327 0.7549 3625961 CBKinase1_015460 Clc1ccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccccc4)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J01 compound treatment 967959.0 45200.0 0.25 655470.0 -36300.0 -0.2 0.0299 0.0932 3625962 CBKinase1_015461 COC(=O)CN(c1ccc2OCCOc2c1)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J02 compound treatment 945563.0 22800.0 0.12 486900.0 -205000.0 -1.15 -0.7284 -0.6271 3625963 CBKinase1_015462 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)NCc2cccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J03 compound treatment 943576.0 20900.0 0.11 631150.0 -60600.0 -0.34 -0.1611 -0.4473 3625964 CBKinase1_015463 COC(=O)c1ccccc1NC(=O)CN(c2ccc3OCCOc3c2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J04 compound treatment 981234.0 58500.0 0.32 689278.0 -2510.0 -0.01 0.2159 0.6751 3625965 CBKinase1_015464 Clc1ccc(cc1)C(=O)Nc2ccccc2C(=O)NCCOc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J05 mock treatment 976363.0 53600.0 0.29 687036.0 -4750.0 -0.03 0.1882 0.6398 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J06 mock treatment 1047840.0 125000.0 0.68 666791.0 -25000.0 -0.14 0.3834 0.5497 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J07 compound treatment 924482.0 1770.0 0.01 709239.0 17400.0 0.1 0.0764 0.7727 3625966 CBKinase1_015465 COc1cccc(NC(=O)COc2ccccc2C(=O)Nc3c(C)cccc3C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J08 compound treatment 1127838.0 205000.0 1.12 723965.0 32200.0 0.18 0.9201 0.8111 3625967 CBKinase1_015466 CSc1cccc(NC(=O)CN(c2ccc3OCCOc3c2)S(=O)(=O)C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J09 compound treatment 1065891.0 143000.0 0.78 762314.0 70500.0 0.4 0.8338 0.9508 1711205 CBKinase1_015467 O=C(CSc1nnc[nH]1)NCc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J10 compound treatment 1208466.0 286000.0 1.56 839408.0 148000.0 0.83 1.6915 0.9567 3625968 CBKinase1_015468 COCCCNC(=O)c1cc(nc2c(C)cc(C)cc12)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J11 compound treatment 1115645.0 193000.0 1.05 773266.0 81500.0 0.46 1.0695 0.9308 3625969 CBKinase1_015469 COc1ccc(NC(=O)CSc2nc3sc4CCCCc4c3c(=O)n2c5ccccc5)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J12 compound treatment 919919.0 -2800.0 -0.02 691093.0 -696.0 0.0 -0.0136 -0.8609 3625970 CBKinase1_015470 [O-][N+](=O)c1ccc(NC(=O)NCc2ccccn2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J13 compound treatment 1113503.0 191000.0 1.04 744024.0 52200.0 0.29 0.9447 0.8728 3625971 CBKinase1_015471 [O-][N+](=O)c1cccc(NC(=O)CSc2nc(cs2)c3ccc(Cl)cc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J14 compound treatment 1100555.0 178000.0 0.97 753960.0 62200.0 0.35 0.9343 0.9052 3625972 CBKinase1_015472 Cn1c(Cc2cccc3ccccc23)nnc1SCC(=O)N4CCc5ccccc45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J15 compound treatment 1013095.0 90400.0 0.49 768257.0 76500.0 0.43 0.6537 0.9977 3625973 CBKinase1_015473 Brc1ccccc1NC(=O)CCn2cnc3ccccc3c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J16 compound treatment 967749.0 45000.0 0.25 702054.0 10300.0 0.06 0.2148 0.8503 3625974 CBKinase1_015474 Clc1ccc(NC(=O)CSc2nc3ccccc3c(=O)[nH]2)c(Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J17 compound treatment 1060853.0 138000.0 0.75 695974.0 4180.0 0.02 0.55 0.7289 3625975 CBKinase1_015475 O=C(CSc1nc2sc3CCCCc3c2c(=O)n1C4CCCCC4)Nc5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J18 compound treatment 1058478.0 136000.0 0.74 745287.0 53500.0 0.3 0.7373 0.9214 1873464 CBKinase1_015476 COc1cc(Cl)c(C)cc1NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3ccccc3F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J19 compound treatment 1001289.0 78600.0 0.43 722829.0 31000.0 0.17 0.427 0.9218 3625976 CBKinase1_015477 Cc1cc(C)c(NC(=O)CSc2nc(cs2)c3ccc(F)cc3)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J20 compound treatment 1040380.0 118000.0 0.64 652372.0 -39400.0 -0.22 0.2971 0.4371 3625977 CBKinase1_015478 COc1ccc(C)cc1NC(=O)CNS(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J21 mock treatment 996488.0 73800.0 0.4 687456.0 -4330.0 -0.02 0.2675 0.663 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J22 mock treatment 904901.0 -17800.0 -0.1 659681.0 -32100.0 -0.18 -0.1967 -0.9576 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J23 compound treatment 847170.0 -75500.0 -0.41 668146.0 -23600.0 -0.13 -0.3859 -0.8903 3625978 CBKinase1_015479 Clc1ccc(NC(=O)NCCc2c[nH]c3ccccc23)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 J24 compound treatment 729041.0 -194000.0 -1.06 624340.0 -67400.0 -0.38 -1.0165 -0.9046 3625979 CBKinase1_015480 CC(=O)CCc1ccc(Oc2ccc(cn2)C(F)(F)F)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K01 compound treatment 969472.0 46800.0 0.26 687954.0 -3840.0 -0.02 0.1652 0.6449 3625980 CBKinase1_015481 COc1ccccc1NC(=O)CSc2nnc(C)[nH]2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K02 compound treatment 784502.0 -138000.0 -0.75 448006.0 -244000.0 -1.37 -1.5052 -0.9602 3625981 CBKinase1_015482 CCC(Sc1nnc(c2ccc(NC(=O)C)cc2)n1C)C(=O)Nc3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K03 compound treatment 877344.0 -45400.0 -0.25 465303.0 -226000.0 -1.28 -1.0778 -0.8289 3625982 CBKinase1_015483 OCCSCC(=O)Nc1cccc2ccccc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K04 compound treatment 868849.0 -53900.0 -0.29 594038.0 -97800.0 -0.55 -0.5975 -0.9568 3625983 CBKinase1_015484 CC(=O)Nc1ccc(cc1)c2nnc(SCC(=O)n3c4CCCCc4c5ccccc35)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K05 compound treatment 906248.0 -16500.0 -0.09 559066.0 -133000.0 -0.75 -0.5925 -0.7864 3625984 CBKinase1_015485 CC(=O)Nc1ccc(NC(=O)CSc2nncn2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K06 compound treatment 921499.0 -1220.0 -0.01 577749.0 -114000.0 -0.64 -0.4592 -0.7144 3625985 CBKinase1_015486 Cc1ccc(CN(CC(=O)O)S(=O)(=O)c2ccc(Br)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K07 mock treatment 876774.0 -45900.0 -0.25 681361.0 -10400.0 -0.06 -0.2189 -0.8498 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K08 mock treatment 827471.0 -95200.0 -0.52 623443.0 -68300.0 -0.39 -0.6401 -0.9891 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K09 compound treatment 818974.0 -104000.0 -0.57 612601.0 -79200.0 -0.45 -0.7161 -0.993 1983959 CBKinase1_015487 Cc1cccc(C)c1OCc2nnc3c4cnn(c5ccccc5)c4ncn23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K10 compound treatment 853345.0 -69400.0 -0.38 673475.0 -18300.0 -0.1 -0.3408 -0.8682 3625986 CBKinase1_015488 Cn1c(SCC(=O)c2ccc-3c(Cc4ccccc43)c2)nnc1c5cccc(N)c5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K11 compound treatment 988606.0 65900.0 0.36 648482.0 -43300.0 -0.24 0.0818 0.1881 3625987 CBKinase1_015489 O=C(CSc1nc2scc(c3ccco3)c2c(=O)n1c4ccccc4)N5CCOCC5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K12 compound treatment 1070658.0 148000.0 0.81 860888.0 169000.0 0.95 1.2451 0.9966 3625988 CBKinase1_015490 Cc1nnc(SCC(=O)Nc2cccc(C)c2C)s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K13 compound treatment 811165.0 -112000.0 -0.61 814361.0 123000.0 0.69 0.0579 0.0628 3625989 CBKinase1_015491 Cc1ccccc1OCC(=O)Nc2ccc(cc2O)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K14 compound treatment 949823.0 27100.0 0.15 653675.0 -38100.0 -0.21 -0.0473 -0.1812 1800668 CBKinase1_015492 CCC(Sc1nnc(C)s1)C(=O)Nc2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K15 mock treatment 1021200.0 98500.0 0.54 640125.0 -51700.0 -0.29 0.1743 0.285 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K16 mock treatment 958224.0 35500.0 0.19 662799.0 -29000.0 -0.16 0.0215 0.0849 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K17 compound treatment 879717.0 -43000.0 -0.23 748251.0 56500.0 0.32 0.059 0.1493 3625990 CBKinase1_015493 OC(=O)c1cc(Cl)ccc1NC(=O)COc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K18 compound treatment 951091.0 28400.0 0.15 644524.0 -47300.0 -0.27 -0.0788 -0.2558 3625991 CBKinase1_015494 COc1ccccc1OCC(=O)Nc2ccc(cc2)c3nc4cc(C)ccc4[nH]3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K19 compound treatment 763139.0 -160000.0 -0.87 549899.0 -142000.0 -0.8 -1.1815 -0.9991 3625992 CBKinase1_015495 [O-][N+](=O)c1ccc(cc1NCc2cccnc2)N3CCN(CC3)C(=O)c4ccccc4Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K20 compound treatment 871925.0 -50800.0 -0.28 700756.0 8970.0 0.05 -0.1603 -0.5689 3625993 CBKinase1_015496 Cn1c(SCC(=O)Nc2ccc(Cl)cc2)nnc1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K21 compound treatment 814368.0 -108000.0 -0.59 649785.0 -42000.0 -0.24 -0.5857 -0.9192 3026207 CBKinase1_015497 COc1ccc(NC(=O)CC2SC(=NC2=O)Nc3ccc(OC)cc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K22 compound treatment 939255.0 16500.0 0.09 661212.0 -30600.0 -0.17 -0.058 -0.2982 3625994 CBKinase1_015498 Ic1ccc(NC(=O)CNS(=O)(=O)c2ccccc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K23 mock treatment 747393.0 -175000.0 -0.96 587238.0 -105000.0 -0.59 -1.0935 -0.9729 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 K24 mock treatment 789374.0 -133000.0 -0.73 533644.0 -158000.0 -0.89 -1.1451 -0.9949 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L01 compound treatment 561377.0 -361000.0 -1.97 598165.0 -93600.0 -0.53 -1.7681 -0.8658 3625995 CBKinase1_015499 Cc1ccnc(NC(c2ccc(cc2)[N+](=O)[O-])c3ccc4ccc(C)nc4c3O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L02 compound treatment 926641.0 3930.0 0.02 637654.0 -54100.0 -0.31 -0.2006 -0.6558 3625996 CBKinase1_015500 CCOc1ccc(NC(=O)C(C)Sc2nnc(C)n2c3ccccc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L03 compound treatment 866170.0 -56500.0 -0.31 606138.0 -85700.0 -0.48 -0.5597 -0.9767 3625997 CBKinase1_015501 CC(Oc1cccc(Cl)c1)c2nc(no2)c3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L04 compound treatment 871115.0 -51600.0 -0.28 650680.0 -41100.0 -0.23 -0.363 -0.9953 3625998 CBKinase1_015502 COc1ccc(cc1OC)c2nnc(SCC(=O)Nc3ccc(Cl)cc3Cl)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L05 compound treatment 925296.0 2580.0 0.01 585796.0 -106000.0 -0.6 -0.4125 -0.6902 3625999 CBKinase1_015503 COc1cccc(NC(=O)c2cc(ccc2NC(=O)CN3CCCCCC3)[N+](=O)[O-])c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L06 compound treatment 958722.0 36000.0 0.2 605277.0 -86500.0 -0.49 -0.2058 -0.3914 1221372 CBKinase1_015504 Cc1ccnc(NC(c2ccsc2)c3ccc4ccc(C)nc4c3O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L07 mock treatment 987138.0 64400.0 0.35 714044.0 22300.0 0.13 0.3374 0.9035 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L08 mock treatment 1059988.0 137000.0 0.75 688981.0 -2810.0 -0.02 0.5187 0.692 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L09 compound treatment 966176.0 43500.0 0.24 659958.0 -31800.0 -0.18 0.0409 0.1375 3626000 CBKinase1_015505 OC1(CC(=O)c2ccccc2)C(=O)Nc3ccc(cc31)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L10 compound treatment 1004081.0 81400.0 0.44 607353.0 -84400.0 -0.48 -0.0224 -0.0344 3626001 CBKinase1_015506 CS(=O)(=O)N(CC(=O)Nc1ccccc1c2ccccc2)c3ccc4OCCOc4c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L11 compound treatment 974621.0 51900.0 0.28 712013.0 20200.0 0.11 0.281 0.9199 1453641 CBKinase1_015507 CN(C)c1ccc(cc1)C(Nc2cc(C)ccn2)c3ccc4ccc(C)nc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L12 compound treatment 1032042.0 109000.0 0.6 697671.0 5880.0 0.03 0.4455 0.7452 3626002 CBKinase1_015508 OC1(CC(=O)c2ccccn2)C(=O)Nc3ccc(Cl)cc31 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L13 compound treatment 1040900.0 118000.0 0.65 687523.0 -4270.0 -0.02 0.4392 0.6803 3626003 CBKinase1_015509 CS(=O)(=O)N(CC(=O)Nc1ccc(F)cc1F)c2ccc3OCCOc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L14 compound treatment 961811.0 39100.0 0.21 673496.0 -18300.0 -0.1 0.078 0.3291 3626004 CBKinase1_015510 COc1ccc(cc1OC)C(=O)Nc2ccc3nc(SCC(=O)N4CCOCC4)sc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L15 mock treatment 1017579.0 94900.0 0.52 606367.0 -85400.0 -0.48 0.0258 0.0364 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L16 mock treatment 959065.0 36300.0 0.2 669605.0 -22200.0 -0.13 0.0519 0.2213 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L17 compound treatment 1090799.0 168000.0 0.92 659331.0 -32500.0 -0.18 0.5195 0.5552 3626005 CBKinase1_015511 Cn1c(SCC(=O)c2ccc(F)cc2)nnc1c3cccc(c3)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L18 compound treatment 1036445.0 114000.0 0.62 688962.0 -2830.0 -0.02 0.4278 0.6887 1159095 CBKinase1_015512 COC(=O)c1cc(OC)c(OC)cc1NC(=O)COc2ccc(Br)cc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L19 compound treatment 883636.0 -39100.0 -0.21 637296.0 -54500.0 -0.31 -0.368 -0.9841 3626006 CBKinase1_015513 Cc1occc1c2nnc(SCC(=O)Nc3cccc(Cl)c3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L20 compound treatment 922588.0 -127.0 0.0 606171.0 -85600.0 -0.48 -0.3417 -0.7081 3626007 CBKinase1_015514 COc1ccc(cc1NC(=O)COc2cccc(C)c2)c3nn(C)c(=O)c4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L21 compound treatment 830248.0 -92500.0 -0.5 580970.0 -111000.0 -0.62 -0.7986 -0.9944 3626008 CBKinase1_015515 COc1ccc(CCNC(=O)Nc2ccc(cc2)[N+](=O)[O-])cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L22 compound treatment 960325.0 37600.0 0.21 644157.0 -47600.0 -0.27 -0.0446 -0.1321 3118544 CBKinase1_015516 C(Cn1c2ccccc2c3nc4ccccc4nc13)N5CCOCC5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L23 mock treatment 891648.0 -31100.0 -0.17 558636.0 -133000.0 -0.75 -0.6506 -0.8456 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 L24 mock treatment 995481.0 72800.0 0.4 587650.0 -104000.0 -0.59 -0.1341 -0.1893 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M01 compound treatment 928294.0 5580.0 0.03 747612.0 55800.0 0.31 0.244 0.7719 3626009 CBKinase1_015517 CCC(CCC(=O)Nc1ccccc1[N+](=O)[O-])C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M02 compound treatment 976142.0 53400.0 0.29 736780.0 45000.0 0.25 0.3856 0.9976 3626010 CBKinase1_015518 CS(=O)(=O)N(CC(=O)Nc1ccc2OCCOc2c1)Cc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M03 compound treatment 869819.0 -52900.0 -0.29 788048.0 96300.0 0.54 0.1794 0.2919 3626011 CBKinase1_015519 [O-][N+](=O)c1ccc(NC(=O)CSc2nnc(o2)c3ccc(Cl)cc3Cl)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M04 compound treatment 894080.0 -28600.0 -0.16 762297.0 70500.0 0.4 0.1705 0.3992 3626012 CBKinase1_015520 CCc1cccc(OCC(=O)Nc2sc3CCCCc3c2C(=O)N)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M05 compound treatment 903428.0 -19300.0 -0.11 835754.0 144000.0 0.81 0.4993 0.6102 1751325 CBKinase1_015521 CC(=O)Nc1ccc(NC(=O)CSc2nnc3c4ccccc4n(C)c3n2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M06 compound treatment 951325.0 28600.0 0.16 704706.0 12900.0 0.07 0.1619 0.9396 3626013 CBKinase1_015522 Cc1ccc(OCC(=O)Nc2cccc(c2)c3nnc(o3)c4ccccc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M07 compound treatment 973640.0 50900.0 0.28 808190.0 116000.0 0.66 0.6605 0.927 3626014 CBKinase1_015523 Cc1ccc(cc1)N(C2CS(=O)(=O)C=C2)C(=O)COc3ccc(C)cc3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M08 compound treatment 973435.0 50700.0 0.28 799782.0 108000.0 0.61 0.6262 0.9364 3626015 CBKinase1_015524 Cc1nn(Cc2cccc(c2)C(=O)Nc3ccccc3F)c(C)c1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M09 mock treatment 990475.0 67800.0 0.37 782235.0 90400.0 0.51 0.6221 0.9876 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M10 mock treatment 910404.0 -12300.0 -0.07 828372.0 137000.0 0.77 0.4968 0.6429 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M11 compound treatment 951405.0 28700.0 0.16 806011.0 114000.0 0.64 0.566 0.8542 3626016 CBKinase1_015525 Clc1ccccc1OCC(=O)Nc2ccccc2C(=O)Nc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M12 compound treatment 952822.0 30100.0 0.16 787423.0 95600.0 0.54 0.4974 0.8826 3626017 CBKinase1_015526 O=C(Oc1ccc(cc1)c2ccccc2)C(Cc3ccccc3)N4C(=O)C5C6CCC(C6)C5C4=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M13 mock treatment 745395.0 -177000.0 -0.97 757293.0 65500.0 0.37 -0.4235 -0.4087 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M14 mock treatment 715689.0 -207000.0 -1.13 769945.0 78200.0 0.44 -0.4877 -0.4021 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M15 compound treatment 957680.0 35000.0 0.19 808679.0 117000.0 0.66 0.6008 0.876 3626018 CBKinase1_015527 CCOc1cc(ccc1O)C(Nc2cccc(C)n2)c3ccc4ccc(C)nc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M16 compound treatment 1000980.0 78300.0 0.43 911606.0 220000.0 1.24 1.1782 0.899 3626019 CBKinase1_015528 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)CN4CCN(CC4)C(=O)C5CCCO5)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M17 compound treatment 862260.0 -60500.0 -0.33 691112.0 -677.0 0.0 -0.2361 -0.7152 3626020 CBKinase1_015529 Oc1cc(ccc1NC(=O)COc2ccccc2Cl)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M18 compound treatment 962634.0 39900.0 0.22 795017.0 103000.0 0.58 0.5655 0.9102 1863690 CBKinase1_015530 COc1cc(CNC2(CC3CC4CC(C3)C2)C4)ccc1OCC(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M19 compound treatment 933158.0 10400.0 0.06 779508.0 87700.0 0.49 0.3899 0.7835 3626021 CBKinase1_015531 CCn1c(SCC(=O)Nc2cccc(Cl)c2C)nnc1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M20 compound treatment 893781.0 -28900.0 -0.16 771882.0 80100.0 0.45 0.2075 0.4339 3626022 CBKinase1_015532 Cn1c(SCC(=O)Nc2ccc(F)cc2)nnc1c3ccc(cc3)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M21 compound treatment 778975.0 -144000.0 -0.78 753619.0 61800.0 0.35 -0.3085 -0.3593 3626023 CBKinase1_015533 CCn1c(SCc2nc(O)c3ccccc3n2)nnc1c4cccnc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M22 compound treatment 887807.0 -34900.0 -0.19 687534.0 -4260.0 -0.02 -0.1517 -0.7899 3626024 CBKinase1_015534 Cc1[nH]c2ccccc2c1CCNS(=O)(=O)c3cc(ccc3C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M23 compound treatment 866604.0 -56100.0 -0.31 766129.0 74300.0 0.42 0.0797 0.1535 3626025 CBKinase1_015535 COc1ccc(NC(=O)CSc2nnc(c3ccc(Br)cc3)n2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 M24 compound treatment 1012786.0 90100.0 0.49 775493.0 83700.0 0.47 0.6813 0.9998 3626026 CBKinase1_015536 O=C(Nc1ccccc1C(=O)NCCN2CCOCC2)c3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N01 compound treatment 891482.0 -31200.0 -0.17 742633.0 50800.0 0.29 0.0821 0.2461 3626027 CBKinase1_015537 [O-][N+](=O)c1cccc(c1)C(=O)Nc2c(Cl)cc(Cl)cc2C(=O)NCc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N02 compound treatment 966873.0 44200.0 0.24 742523.0 50700.0 0.29 0.3727 0.9964 1617630 CBKinase1_015538 COc1cccc(c1)C(Nc2cc(C)ccn2)c3ccc4ccc(C)nc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N03 compound treatment 930198.0 7480.0 0.04 773584.0 81800.0 0.46 0.3549 0.7668 3626028 CBKinase1_015539 Cc1sc2nc(SCC(=O)Nc3cccc(C)c3C)n(C)c(=O)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N04 compound treatment 904214.0 -18500.0 -0.1 752736.0 60900.0 0.34 0.1715 0.4789 3626029 CBKinase1_015540 COc1cc(NC(=O)COc2ccc(cc2)[N+](=O)[O-])ccc1NC(=O)c3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N05 compound treatment 1031082.0 108000.0 0.59 735261.0 43500.0 0.25 0.5916 0.9239 3626030 CBKinase1_015541 Cc1cccc(OCC(=O)Nc2ccccc2C(=O)NC3CCCCC3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N06 compound treatment 984803.0 62100.0 0.34 643528.0 -48300.0 -0.27 0.0473 0.1089 3626031 CBKinase1_015542 Cc1ccc(NC(=O)CSc2nnc(c3cccc4ccccc34)n2c5ccccc5)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N07 compound treatment 897979.0 -24700.0 -0.14 757903.0 66100.0 0.37 0.168 0.4239 3626032 CBKinase1_015543 [O-][N+](=O)c1ccc(NC(=O)CN2CCN(CC2)C3CCCC3)c(c1)C(=O)Nc4ccccc4F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N08 compound treatment 1036531.0 114000.0 0.62 745939.0 54100.0 0.31 0.6552 0.9464 1754965 CBKinase1_015544 CCn1c(SCC(=O)Nc2ccccc2C)nc3ccccc3c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N09 mock treatment 938749.0 16000.0 0.09 711472.0 19700.0 0.11 0.1403 0.9931 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N10 mock treatment 868672.0 -54000.0 -0.3 805493.0 114000.0 0.64 0.2445 0.3466 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N11 compound treatment 990440.0 67700.0 0.37 717460.0 25700.0 0.14 0.3638 0.9162 3626033 CBKinase1_015545 Cc1ccc(NC(=O)CCCOc2ccccc2)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N12 compound treatment 1044327.0 122000.0 0.66 809338.0 118000.0 0.66 0.938 1.0 3626034 CBKinase1_015546 COc1cc2c(cc1NC(=O)C(C)Oc3cccc(Cl)c3)oc4ccccc42 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N13 mock treatment 1073242.0 151000.0 0.82 766505.0 74700.0 0.42 0.8789 0.9518 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N14 mock treatment 908760.0 -14000.0 -0.08 768455.0 76700.0 0.43 0.2517 0.5736 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N15 compound treatment 800772.0 -122000.0 -0.67 580274.0 -112000.0 -0.63 -0.9152 -0.9996 1593484 CBKinase1_015547 Cc1ccnc(NC(c2cccc(F)c2)c3ccc4ccc(C)nc4c3O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N16 compound treatment 891617.0 -31100.0 -0.17 740097.0 48300.0 0.27 0.0725 0.2259 3626035 CBKinase1_015548 CCC(=O)Nc1ccc2nc(SCc3ccccc3C#N)sc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N17 compound treatment 1068165.0 145000.0 0.79 1081258.0 389000.0 2.2 2.1137 0.9055 3626036 CBKinase1_015549 CS(=O)(=O)N(CC(=O)Nc1cccnc1)c2ccc3OCCOc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N18 compound treatment 896585.0 -26100.0 -0.14 699003.0 7210.0 0.04 -0.0721 -0.4862 3626037 CBKinase1_015550 CC(N1C(=O)c2ccccc2C1=O)C(=O)Oc3cccc4cccnc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N19 compound treatment 929652.0 6940.0 0.04 774687.0 82900.0 0.47 0.3572 0.7619 3626038 CBKinase1_015551 COC(=O)c1ccc(OCC(=O)Nc2ccc(cc2)C(=O)C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N20 compound treatment 1054382.0 132000.0 0.72 734884.0 43100.0 0.24 0.68 0.8963 3626039 CBKinase1_015552 COCCNc1ncnc2n(ncc12)c3cccc(C)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N21 compound treatment 970499.0 47800.0 0.26 763755.0 72000.0 0.41 0.4713 0.9772 3626040 CBKinase1_015553 CCc1ccccc1NC(=O)CSc2nnc(c3cccc(OC)c3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N22 compound treatment 1035353.0 113000.0 0.61 697630.0 5840.0 0.03 0.4581 0.7439 1876327 CBKinase1_015554 Cc1cccc(c1)n2c(N)cc(=O)nc2SCC(=O)Nc3ccccc3C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N23 compound treatment 852492.0 -70200.0 -0.38 726853.0 35100.0 0.2 -0.1313 -0.3045 3626041 CBKinase1_015555 CCOc1ccc(NC(=O)C(C)Sc2nc3ccc(F)cc3[nH]2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 N24 compound treatment 973744.0 51000.0 0.28 705159.0 13400.0 0.08 0.2503 0.8672 3626042 CBKinase1_015556 COC(=O)c1ccccc1NC(=O)CSc2nnc([nH]2)c3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O01 compound treatment 913587.0 -9130.0 -0.05 762406.0 70600.0 0.4 0.2462 0.6138 3118511 CBKinase1_015557 CCNc1nc(OCCO)nc(n1)N(C)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O02 compound treatment 913923.0 -8790.0 -0.05 700213.0 8420.0 0.05 -4.0E-4 -0.0055 3626043 CBKinase1_015558 OC(CNC(=O)c1ccc(cc1)S(=O)(=O)N2CCOCC2)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O03 compound treatment 991219.0 68500.0 0.37 758535.0 66700.0 0.38 0.5305 1.0 3626044 CBKinase1_015559 Cc1cc2ccccc2n3c(SCC(=O)N)nnc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O04 compound treatment 973031.0 50300.0 0.27 706244.0 14500.0 0.08 0.2519 0.879 3626045 CBKinase1_015560 COc1cc(cc(OC)c1OC)c2nnc(SCC(=O)c3ccc(Cl)cc3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O05 compound treatment 1049093.0 126000.0 0.69 771537.0 79700.0 0.45 0.8057 0.9784 1451779 CBKinase1_015561 Brc1ccc(cc1)C(=O)CSc2nc3ccccc3c(=O)n2CC4CCCO4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O06 compound treatment 1006046.0 83300.0 0.45 722815.0 31000.0 0.17 0.4453 0.9137 3626046 CBKinase1_015562 Cc1cccc(C)c1OCC(=O)Nc2ccc(O)cc2C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O07 compound treatment 975255.0 52500.0 0.29 733273.0 41500.0 0.23 0.3682 0.9949 3626047 CBKinase1_015563 O=C(CCN1C(=O)C2C(C3C=CC2C4CC43)C1=O)Oc5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O08 compound treatment 964333.0 41600.0 0.23 658156.0 -33600.0 -0.19 0.0266 0.0899 1254107 CBKinase1_015564 COc1cccc(C2CC(=O)NC(=C2C#N)SCC(=O)Nc3ccccc3Cl)c1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O09 compound treatment 999624.0 76900.0 0.42 718157.0 26400.0 0.15 0.402 0.9025 3024129 CBKinase1_015565 CC(CC(=O)O)CC(=O)Nc1cccc(c1)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O10 compound treatment 998835.0 76100.0 0.42 675855.0 -15900.0 -0.09 0.2303 0.5418 3626048 CBKinase1_015566 [O-][N+](=O)c1ccc(cc1)c2nnc(SCC(=O)Nc3ccc(Cl)cc3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O11 mock treatment 1016086.0 93400.0 0.51 738450.0 46700.0 0.26 0.5464 0.9526 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O12 mock treatment 989210.0 66500.0 0.36 717589.0 25800.0 0.15 0.3595 0.9193 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O13 compound treatment 1055384.0 133000.0 0.72 697445.0 5660.0 0.03 0.5347 0.7375 3626049 CBKinase1_015567 [O-][N+](=O)c1ccc(cc1)S(=O)(=O)c2ccccc2C(=O)NCC3CCCO3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O14 compound treatment 1026511.0 104000.0 0.57 734107.0 42300.0 0.24 0.5694 0.926 3025407 CBKinase1_015568 CC(C)(C)c1cc(cc(c1)C(C)(C)C)C(=O)NCCCn2ccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O15 compound treatment 1004360.0 81600.0 0.45 742610.0 50800.0 0.29 0.5177 0.9771 3626050 CBKinase1_015569 [O-][N+](=O)c1cccc(NC(=O)c2ccc(Cn3nnc4ccccc34)cc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O16 compound treatment 1016350.0 93600.0 0.51 706758.0 15000.0 0.08 0.4211 0.8128 3626051 CBKinase1_015570 CC(C)C(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nccc(/C=C/c3ccccc3F)n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O17 compound treatment 896781.0 -25900.0 -0.14 672063.0 -19700.0 -0.11 -0.1787 -0.9928 3626053 CBKinase1_015571 [O-][N+](=O)c1ccccc1S(=O)(=O)c2ccccc2C(=O)Nc3ccc(F)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O18 compound treatment 937867.0 15200.0 0.08 735167.0 43400.0 0.24 0.2314 0.8964 3626054 CBKinase1_015572 CCOC(=O)c1c(NC(=O)c2nn(CC)cc2Br)c(C#N)nn1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O19 compound treatment 989538.0 66800.0 0.36 639044.0 -52700.0 -0.3 0.0477 0.1015 3626055 CBKinase1_015573 CCn1c(SCC(=O)Nc2ccc(C)cc2)nnc1c3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O20 compound treatment 972765.0 50000.0 0.27 641396.0 -50400.0 -0.28 -0.0076 -0.0194 3211468 CBKinase1_015574 OC(=O)C1CCCCC1C(=O)Nc2ccc(cc2)C(=O)N3CCCCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O21 compound treatment 908345.0 -14400.0 -0.08 642528.0 -49300.0 -0.28 -0.2518 -0.8727 3626056 CBKinase1_015575 Clc1ccc(COc2ccccc2CNc3nnc[nH]3)c(Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O22 compound treatment 949266.0 26600.0 0.14 677978.0 -13800.0 -0.08 0.0475 0.2884 3626057 CBKinase1_015576 CS(=O)(=O)N(CC(=O)Nc1cccc(Cl)c1Cl)Cc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O23 compound treatment 936904.0 14200.0 0.08 700803.0 9010.0 0.05 0.0907 0.9791 3626058 CBKinase1_015577 CCn1c(SCC(=O)Nc2ccc(C)cc2)nnc1c3ccc(N)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 O24 compound treatment 951181.0 28500.0 0.16 617504.0 -74300.0 -0.42 -0.1862 -0.4169 3626059 CBKinase1_015578 CS(=O)(=O)N(CC(=O)Nc1cccc(c1)C(F)(F)F)Cc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P01 compound treatment 890686.0 -32000.0 -0.17 734705.0 42900.0 0.24 0.0474 0.1588 3626060 CBKinase1_015579 Clc1ccccc1c2nnc(SCC(=O)NC3CCCCC3)[nH]2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P02 compound treatment 922618.0 -97.3 0.0 745851.0 54100.0 0.3 0.2151 0.7059 3626061 CBKinase1_015580 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)Nc2cc(Cl)c(Cl)cc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P03 compound treatment 861259.0 -61500.0 -0.34 698415.0 6630.0 0.04 -0.2108 -0.6245 1599355 CBKinase1_015581 O=C(Cn1cnc2ccccc2c1=O)Nc3ccc(Oc4ccccc4)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P04 compound treatment 959530.0 36800.0 0.2 720960.0 29200.0 0.16 0.2584 0.995 3626062 CBKinase1_015582 Cc1ccc(cc1S(=O)(=O)NCCOc2ccccc2Cl)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P05 compound treatment 927796.0 5080.0 0.03 767593.0 75800.0 0.43 0.3217 0.7514 3626063 CBKinase1_015583 COc1cc(NC(=O)COc2ccccc2C)ccc1NC(=O)c3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P06 compound treatment 974686.0 52000.0 0.28 641164.0 -50600.0 -0.29 -0.0011 -0.0028 3626064 CBKinase1_015584 COC(=O)c1ccccc1NC(=O)COc2c(Cl)cc(Cl)c3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P07 compound treatment 1046603.0 124000.0 0.68 923791.0 232000.0 1.31 1.4029 0.9529 3626065 CBKinase1_015585 Cc1cccc(NC(=O)CSc2nnc(c3ccccc3)n2C4CCCCC4)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P08 compound treatment 962180.0 39500.0 0.22 750489.0 58700.0 0.33 0.3863 0.9784 3626066 CBKinase1_015586 Cc1cccc(NC(=O)CSc2nnc(c3cccc(Br)c3)n2c4ccccc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P09 compound treatment 1007348.0 84600.0 0.46 712681.0 20900.0 0.12 0.41 0.8598 1120539 CBKinase1_015587 Clc1ccccc1NC(=O)NCc2ccccn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P10 compound treatment 987615.0 64900.0 0.35 818183.0 126000.0 0.71 0.7543 0.948 3626067 CBKinase1_015588 [O-][N+](=O)c1cccc(COc2ccc(cc2)c3cnc4ccccc4n3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P11 mock treatment 962076.0 39400.0 0.21 821326.0 130000.0 0.73 0.6682 0.878 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P12 mock treatment 992938.0 70200.0 0.38 787340.0 95600.0 0.54 0.6519 0.9861 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P13 compound treatment 943952.0 21200.0 0.12 838008.0 146000.0 0.82 0.6647 0.7987 3626068 CBKinase1_015589 CS(=O)(=O)N(CC(=O)NC1CCCC1)c2ccc3OCCOc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P14 compound treatment 1132854.0 210000.0 1.15 770509.0 78700.0 0.44 1.125 0.9146 3626069 CBKinase1_015590 CS(=O)(=O)N(CC(=O)Nc1ccccc1Br)Cc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P15 compound treatment 730100.0 -193000.0 -1.05 722692.0 30900.0 0.17 -0.6204 -0.5821 3626070 CBKinase1_015591 CCn1nc(C)c(NC(=O)CSc2nnc(c3ccco3)n2C)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P16 compound treatment 1069109.0 146000.0 0.8 701601.0 9810.0 0.06 0.6043 0.7542 3626071 CBKinase1_015592 Cn1c(SCC(=O)Nc2ccccc2F)nnc1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P17 compound treatment 994733.0 72000.0 0.39 775110.0 83300.0 0.47 0.6101 0.9961 3626072 CBKinase1_015593 COc1ccc(OC)c(NC(=O)CSc2nc3ccccc3n2C4CCCCC4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P18 compound treatment 939494.0 16800.0 0.09 749136.0 57300.0 0.32 0.2933 0.8731 3626073 CBKinase1_015594 CN(CC(=O)Nc1cccc(c1)[N+](=O)[O-])S(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P19 compound treatment 1040610.0 118000.0 0.64 724830.0 33000.0 0.19 0.5868 0.8758 3626074 CBKinase1_015595 Cc1nnc(SCC(=O)NC2CC2)n1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P20 compound treatment 1004880.0 82200.0 0.45 688660.0 -3130.0 -0.02 0.3047 0.6788 3626075 CBKinase1_015596 Clc1ccc(NC(=O)c2ccco2)c(c1)C(=O)NCc3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P21 compound treatment 1061508.0 139000.0 0.76 698695.0 6910.0 0.04 0.5633 0.7425 3626076 CBKinase1_015597 CCOc1ccc(NC(=O)C(C)Sc2nnnn2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P22 compound treatment 962972.0 40300.0 0.22 701477.0 9690.0 0.05 0.194 0.8567 3626077 CBKinase1_015598 [O-][N+](=O)c1cccc(NC(=O)COc2ccc3cc(Br)ccc3c2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P23 compound treatment 910366.0 -12300.0 -0.07 620774.0 -71000.0 -0.4 -0.3307 -0.8147 3626078 CBKinase1_015599 Cc1ccc(o1)C(=O)CC2(O)C(=O)Nc3c2cc(C)cc3Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2372 P24 compound treatment 946120.0 23400.0 0.13 670366.0 -21400.0 -0.12 0.005 0.0283 3626079 CBKinase1_015600 CC(=O)Nc1ccc(NC(=O)COc2ccccc2C(=O)Nc3cccc(C)c3C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A01 compound treatment 843933.0 115000.0 0.63 803640.0 16700.0 0.09 0.5095 0.8043 3626080 CBKinase1_015601 COC(=O)c1ccccc1NC(=O)COc2ccc([N+](=O)[O-])c(C)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A02 compound treatment 830830.0 102000.0 0.55 809733.0 22800.0 0.13 0.4832 0.8483 3626081 CBKinase1_015602 CC(=O)Nc1ccc(NC(=O)CN(c2ccccc2Br)S(=O)(=O)C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A03 compound treatment 795302.0 66100.0 0.36 799255.0 12300.0 0.07 0.3043 0.8278 3626082 CBKinase1_015603 COc1cc(Br)cc2cc(C(=O)NCCCN3CCOCC3)c(=O)oc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A04 compound treatment 819488.0 90300.0 0.49 834265.0 47300.0 0.27 0.5372 0.9584 1984263 CBKinase1_015604 OCc1cn(CC(=O)Nc2ccccc2)c3ccccc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A05 compound treatment 838535.0 109000.0 0.6 834985.0 48000.0 0.27 0.6136 0.936 3626083 CBKinase1_015605 Clc1ccc(COCCNC2=NS(=O)(=O)c3ccccc23)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A06 compound treatment 779778.0 50600.0 0.28 834367.0 47400.0 0.27 0.3843 0.9999 3626084 CBKinase1_015606 CS(=O)(=O)N(CC(=O)Nc1ccccc1)c2cccc(F)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A07 compound treatment 726715.0 -2460.0 -0.01 836507.0 49600.0 0.28 0.188 0.6723 3626085 CBKinase1_015607 CC(C)(C)NC(=O)c1cccc(NC(=O)COc2ccc3ccccc3c2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A08 compound treatment 876460.0 147000.0 0.8 813820.0 26900.0 0.15 0.6757 0.8258 3626086 CBKinase1_015608 OC(=O)CCN1C(=O)c2ccc(NC(=O)c3cccs3)cc2C1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A09 compound treatment 827890.0 98700.0 0.54 727572.0 -59400.0 -0.33 0.1444 0.2277 3626087 CBKinase1_015609 COc1ccccc1OCC(=O)Nc2cccc(c2)c3nc4ccccc4s3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A10 compound treatment 916994.0 188000.0 1.03 868997.0 82000.0 0.46 1.0521 0.9353 3626088 CBKinase1_015610 Cn1c(SCC(=O)Nc2cc(Cl)cc(Cl)c2)nnc1c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A11 compound treatment 871842.0 143000.0 0.78 824704.0 37800.0 0.21 0.7012 0.8685 3626089 CBKinase1_015611 CC(C)(C)c1ccc(OC(=O)CCN2C(=O)C3C(C4C=CC3C5CC54)C2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A12 compound treatment 880824.0 152000.0 0.83 873844.0 86900.0 0.49 0.9318 0.9686 3626090 CBKinase1_015612 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)Nc2ccc(Cl)c(Cl)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A13 mock treatment 873861.0 145000.0 0.79 822697.0 35700.0 0.2 0.701 0.8599 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A14 mock treatment 868309.0 139000.0 0.76 857751.0 70800.0 0.4 0.8193 0.9548 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A15 compound treatment 801821.0 72600.0 0.4 851087.0 64100.0 0.36 0.5361 0.9989 3626091 CBKinase1_015613 COc1ccc(NC(=O)CNS(=O)(=O)c2c(C)cc(C)cc2C)c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A16 compound treatment 817144.0 88000.0 0.48 816316.0 29400.0 0.17 0.4566 0.8989 1339355 CBKinase1_015614 Cc1ccc(C)c(NC(=O)CSc2cc(C)c3ccccc3n2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A17 compound treatment 836807.0 108000.0 0.59 902897.0 116000.0 0.65 0.8776 0.9986 3626092 CBKinase1_015615 COC(=O)c1ccc(cc1)n2c(CCC(=O)O)ccc2c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A18 compound treatment 859539.0 130000.0 0.71 850300.0 63400.0 0.36 0.7557 0.9491 3626093 CBKinase1_015616 COC(=O)c1ccccc1NC(=O)CN2C(=O)c3cccc4cccc2c34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A19 compound treatment 802569.0 73400.0 0.4 861509.0 74600.0 0.42 0.5805 0.9997 3626094 CBKinase1_015617 CC(=O)Nc1ccc(NC(=O)CNS(=O)(=O)c2c(C)cc(C)cc2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A20 compound treatment 842889.0 114000.0 0.62 953872.0 167000.0 0.94 1.1043 0.9796 3626095 CBKinase1_015618 COc1ccccc1OCC(=O)Nc2ccccc2C(=O)Nc3cccc(c3)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A21 compound treatment 762694.0 33500.0 0.18 829029.0 42100.0 0.24 0.2971 0.9918 3626096 CBKinase1_015619 Cc1nnc(SCC(=O)Nc2ccc(C)c(C)c2)n1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A22 compound treatment 754502.0 25300.0 0.14 818124.0 31200.0 0.18 0.222 0.993 3626097 CBKinase1_015620 CN(CC(=O)Nc1ccc(Cl)c(Cl)c1)S(=O)(=O)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A23 compound treatment 775746.0 46600.0 0.25 830292.0 43300.0 0.24 0.3525 0.9998 3626098 CBKinase1_015621 COC(=O)CSc1ncnc2scc(c3ccc(Cl)cc3)c12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 A24 compound treatment 771778.0 42600.0 0.23 821615.0 34700.0 0.2 0.3026 0.9962 1165502 CBKinase1_015622 Cc1ccc(NC(=O)CSc2ncccn2)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B01 compound treatment 777321.0 48100.0 0.26 850493.0 63500.0 0.36 0.4391 0.9884 3626099 CBKinase1_015623 Clc1ccc(NC(=O)CSc2nc3ccccc3[nH]2)cc1Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B02 compound treatment 810687.0 81500.0 0.45 871057.0 84100.0 0.47 0.6499 0.9995 3626100 CBKinase1_015624 Cc1nnc(SCC(=O)Nc2c(C)cccc2C)n1c3ccc(C)c(C)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B03 compound treatment 829379.0 100000.0 0.55 877191.0 90200.0 0.51 0.7465 0.9993 3626101 CBKinase1_015625 Cc1cccc(c1)n2c(SCC(=O)Nc3ccc(Br)cc3F)nnc2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B04 compound treatment 805343.0 76200.0 0.42 883187.0 96200.0 0.54 0.6776 0.9914 3626102 CBKinase1_015626 Cc1ccc(cc1)c2csc3ncnc(SCC(=O)Nc4ccccc4F)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B05 compound treatment 840159.0 111000.0 0.61 900416.0 113000.0 0.64 0.8807 0.9996 1504059 CBKinase1_015627 CCc1cccc(CC)c1NC(=O)Cn2cnc3sc(C)c(C)c3c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B06 compound treatment 853664.0 124000.0 0.68 876908.0 90000.0 0.51 0.8391 0.9896 3626103 CBKinase1_015628 CCCn1nnc(NC(=O)COc2ccccc2Cl)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B07 compound treatment 848530.0 119000.0 0.65 893589.0 107000.0 0.6 0.8858 0.9992 3626104 CBKinase1_015629 COc1ccc(NC(=O)c2ccccc2NC(=O)COc3cccc(OC)c3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B08 compound treatment 847766.0 119000.0 0.65 911895.0 125000.0 0.7 0.9558 0.9991 3626105 CBKinase1_015630 Clc1ccc(CS(=O)CCSc2nc3ccccc3s2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B09 compound treatment 829583.0 100000.0 0.55 866576.0 79600.0 0.45 0.705 0.9951 3626106 CBKinase1_015631 Cc1cccc(OCC(=O)Nc2cccc(c2)c3nnc(o3)c4ccccc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B10 compound treatment 837598.0 108000.0 0.59 864643.0 77700.0 0.44 0.7282 0.989 3626107 CBKinase1_015632 COc1ccc(C)cc1NC(=O)CNS(=O)(=O)c2c(C)cc(C)cc2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B11 compound treatment 787671.0 58500.0 0.32 861178.0 74200.0 0.42 0.5217 0.9911 3626108 CBKinase1_015633 Cc1cc(ccc1NC(=O)CSc2nnc(c3ccc(Cl)cc3Cl)n2C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B12 compound treatment 828858.0 99700.0 0.54 888700.0 102000.0 0.57 0.7903 0.9997 3626109 CBKinase1_015634 Clc1ccc(NC(=O)CSc2ncnc3sc4CCCc4c23)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B13 mock treatment 875139.0 146000.0 0.8 852251.0 65300.0 0.37 0.8237 0.9384 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B14 mock treatment 826173.0 97000.0 0.53 935770.0 149000.0 0.84 0.9676 0.9754 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B15 compound treatment 844928.0 116000.0 0.63 865285.0 78300.0 0.44 0.7591 0.9846 3626110 CBKinase1_015635 Cc1c(cccc1[N+](=O)[O-])C(=O)Nc2ccccc2C(=O)NCc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B16 compound treatment 851451.0 122000.0 0.67 897882.0 111000.0 0.63 0.9142 0.9995 3626111 CBKinase1_015636 Cn1nnnc1SCC(=O)c2ccc(O)c(O)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B17 compound treatment 889014.0 160000.0 0.87 926887.0 140000.0 0.79 1.1748 0.9987 3626112 CBKinase1_015637 CC(=O)Nc1ccc(NC(=O)CN(c2ccc(Cl)c(c2)C(F)(F)F)S(=O)(=O)C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B18 compound treatment 876331.0 147000.0 0.8 868418.0 81500.0 0.46 0.8928 0.9648 3626113 CBKinase1_015638 COc1ccc(cc1NC(=O)CN(c2ccccc2Br)S(=O)(=O)C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B19 compound treatment 832075.0 103000.0 0.56 860400.0 73500.0 0.41 0.69 0.9887 3626114 CBKinase1_015639 Cc1nnc(SCC(=O)Nc2ccc(C)cc2Br)n1c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B20 compound treatment 719689.0 -9490.0 -0.05 849395.0 62400.0 0.35 0.2123 0.5966 3626115 CBKinase1_015640 Cc1cc(C)c(NC(=O)CN(c2ccc(F)cc2)S(=O)(=O)C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B21 compound treatment 747090.0 17900.0 0.1 807950.0 21000.0 0.12 0.1529 0.9955 3626116 CBKinase1_015641 OC(=O)c1cc(NC(=O)COc2cccc3ccccc23)cc(c1)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B22 compound treatment 827352.0 98200.0 0.54 951794.0 165000.0 0.93 1.036 0.9658 3626117 CBKinase1_015642 CC(N(c1ccccc1)S(=O)(=O)C)C(=O)Nc2c(C)cc(C)cc2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B23 compound treatment 775410.0 46200.0 0.25 803752.0 16800.0 0.09 0.2455 0.9104 3626118 CBKinase1_015643 [O-][N+](=O)c1ccc(cc1NCc2cccnc2)N3CCN(CC3)S(=O)(=O)c4ccc(F)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 B24 compound treatment 818395.0 89200.0 0.49 818534.0 31600.0 0.18 0.4703 0.9069 1636967 CBKinase1_015644 CCOc1ccccc1NC(=O)c2c(NCc3ccc(C)o3)sc4CCCc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C01 compound treatment 799559.0 70400.0 0.38 851119.0 64200.0 0.36 0.5275 0.9995 3626119 CBKinase1_015645 COC(=O)c1ccc(NC(=O)CSc2nnc(o2)c3ccc(Br)cc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C02 compound treatment 799744.0 70600.0 0.39 861587.0 74600.0 0.42 0.5699 0.999 1985832 CBKinase1_015646 CCOC(=O)c1ccccc1NC(=O)CN2C(=O)c3cccc4cccc2c34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C03 compound treatment 808890.0 79700.0 0.44 790503.0 3550.0 0.02 0.3219 0.7389 3626120 CBKinase1_015647 Brc1ccc(OC(=O)CCN2C(=O)C3C(C4C=CC3C5CC54)C2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C04 compound treatment 842384.0 113000.0 0.62 772457.0 -14500.0 -0.08 0.3793 0.6084 3626121 CBKinase1_015648 Cc1cc(NC(=O)CSc2nc3ccccc3[nH]2)ccc1Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C05 compound treatment 781750.0 52600.0 0.29 783430.0 -3520.0 -0.02 0.1889 0.6567 1806165 CBKinase1_015649 CCOc1ccc(NC(=O)C(C)Sc2ccccn2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C06 compound treatment 769421.0 40200.0 0.22 845818.0 58900.0 0.33 0.39 0.98 1590296 CBKinase1_015650 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ccccn3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C07 compound treatment 766537.0 37400.0 0.2 796521.0 9570.0 0.05 0.1824 0.8644 3626122 CBKinase1_015651 COc1ccc(cc1)c2cc(=O)[nH]c(SCC(=O)Nc3cccc(Cl)c3C)n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C08 compound treatment 794858.0 65700.0 0.36 781569.0 -5380.0 -0.03 0.2321 0.645 3626123 CBKinase1_015652 CCOc1ccc(cc1)n2c(SCC(=O)N3CCOCC3)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C09 compound treatment 722969.0 -6210.0 -0.03 807662.0 20700.0 0.12 0.0586 0.4819 3626124 CBKinase1_015653 CC1=CCC(C(C1)C(=O)Nc2cccnc2)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C10 compound treatment 739457.0 10300.0 0.06 763115.0 -23800.0 -0.13 -0.0553 -0.3799 3626125 CBKinase1_015654 CC(=O)c1cccc(NC(=O)CCN2C(=O)c3ccccc3S2(=O)=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C11 mock treatment 733262.0 4090.0 0.02 792843.0 5890.0 0.03 0.0393 0.9812 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C12 mock treatment 773008.0 43800.0 0.24 811119.0 24200.0 0.14 0.2655 0.9643 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C13 compound treatment 770753.0 41600.0 0.23 799992.0 13000.0 0.07 0.2125 0.8906 3626126 CBKinase1_015655 CCc1ccc(NC(=O)CSc2nnc(o2)c3ccc(Br)cc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C14 compound treatment 807958.0 78800.0 0.43 810035.0 23100.0 0.13 0.3961 0.8816 1126272 CBKinase1_015656 Clc1ccc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C15 mock treatment 721210.0 -7970.0 -0.04 776551.0 -10400.0 -0.06 -0.0722 -0.9892 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C16 mock treatment 616505.0 -113000.0 -0.62 720433.0 -66500.0 -0.37 -0.7001 -0.9718 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C17 compound treatment 742428.0 13300.0 0.07 771117.0 -15800.0 -0.09 -0.0119 -0.104 3626127 CBKinase1_015657 Cc1ccc(cc1NC(=O)CN2C(=O)c3ccccc3C2=O)c4nc5ccccc5o4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C18 compound treatment 792440.0 63300.0 0.35 796954.0 10000.0 0.06 0.2841 0.8118 3626128 CBKinase1_015658 Cc1ccc(cc1)n2c(SCC(=O)N3CCOCC3)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C19 compound treatment 742747.0 13600.0 0.07 695773.0 -91200.0 -0.51 -0.311 -0.599 3626129 CBKinase1_015659 Cc1ccc(NC(=O)CSc2nnnn2c3ccc(F)cc3)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C20 compound treatment 677259.0 -51900.0 -0.28 706559.0 -80400.0 -0.45 -0.5208 -0.9745 1463579 CBKinase1_015660 Cc1ccccc1NC(=O)COc2ccc(cc2)N3CC(CC3=O)C(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C21 compound treatment 619835.0 -109000.0 -0.6 796329.0 9380.0 0.05 -0.3847 -0.642 1598033 CBKinase1_015661 Fc1ccc(NC(=O)Cn2cnc3scc(c4ccccc4)c3c2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C22 compound treatment 757842.0 28700.0 0.16 781560.0 -5390.0 -0.03 0.0892 0.5594 1985903 CBKinase1_015662 CCOc1ccccc1NC(=O)CN2C(=O)c3cccc4cccc2c34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C23 compound treatment 750227.0 21100.0 0.11 748126.0 -38800.0 -0.22 -0.0735 -0.2972 3626130 CBKinase1_015663 Cc1nnc(SCC(=O)Nc2ccccc2C(F)(F)F)n1c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 C24 compound treatment 740794.0 11600.0 0.06 715676.0 -71300.0 -0.4 -0.2392 -0.5882 3626131 CBKinase1_015664 Cc1ccc(cc1)S(=O)(=O)NCC(=O)Nc2ccc(Cl)cc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D01 compound treatment 674978.0 -54200.0 -0.3 841716.0 54800.0 0.31 0.009 0.0212 3626132 CBKinase1_015665 CC(=O)c1ccc(cc1)n2c(CCC(=O)O)ccc2c3ccc(F)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D02 compound treatment 582730.0 -146000.0 -0.8 803648.0 16700.0 0.09 -0.4988 -0.6196 3626133 CBKinase1_015666 CN(c1cccc(NC(=O)c2ccc(CN3CCc4ccccc4C3)cc2)c1)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D03 compound treatment 590137.0 -139000.0 -0.76 777531.0 -9420.0 -0.05 -0.5743 -0.7547 3626134 CBKinase1_015667 CCn1c(SCC(=O)Nc2ccc(Br)cc2Cl)nnc1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D04 compound treatment 693454.0 -35700.0 -0.2 773950.0 -13000.0 -0.07 -0.1897 -0.9106 1710326 CBKinase1_015668 CC1CCc2c(C1)sc3ncn(CC(=O)Nc4ccccc4F)c(=O)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D05 compound treatment 676542.0 -52600.0 -0.29 714785.0 -72200.0 -0.41 -0.4908 -0.9855 1750172 CBKinase1_015669 COc1ccc(cc1)c2nnc(SCC(=O)N3c4ccccc4Sc5ccccc35)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D06 compound treatment 635138.0 -94000.0 -0.51 767605.0 -19300.0 -0.11 -0.4401 -0.8386 3626135 CBKinase1_015670 COc1ccc(OC)c(c1)S(=O)(=O)Nc2cccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D07 compound treatment 653633.0 -75500.0 -0.41 786820.0 -129.0 0.0 -0.2921 -0.7083 3626136 CBKinase1_015671 COc1ccc(C)cc1NC(=O)CNS(=O)(=O)c2ccc(C)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D08 compound treatment 706886.0 -22300.0 -0.12 793181.0 6230.0 0.04 -0.0612 -0.4833 1438203 CBKinase1_015672 COC(=O)c1ccc(NC(=O)CSc2cc(C)c3ccccc3n2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D09 compound treatment 682362.0 -46800.0 -0.26 786875.0 -73.7 0.0 -0.181 -0.7083 3626137 CBKinase1_015673 Cc1cccc(c1)n2c(SCC(=O)Nc3ccc(C)cc3Br)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D10 compound treatment 680088.0 -49100.0 -0.27 753542.0 -33400.0 -0.19 -0.3226 -0.9851 3626138 CBKinase1_015674 Clc1ccc(cc1)c2csc3ncnc(SCc4ccco4)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D11 mock treatment 650895.0 -78300.0 -0.43 787569.0 620.0 0.0 -0.2997 -0.7013 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D12 mock treatment 699762.0 -29400.0 -0.16 812391.0 25400.0 0.14 -0.0122 -0.0564 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D13 compound treatment 689869.0 -39300.0 -0.21 831048.0 44100.0 0.25 0.024 0.0731 3626139 CBKinase1_015675 CCc1cc(Br)cc(C)c1NC(=O)CSc2nnc(c3ccc(Cl)cc3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D14 compound treatment 700031.0 -29100.0 -0.16 833897.0 46900.0 0.26 0.0746 0.2416 1358825 CBKinase1_015676 Cc1cc(C(=O)CSc2nnc3sc4ccccc4n23)c(C)n1Cc5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D15 mock treatment 672926.0 -56300.0 -0.31 818558.0 31600.0 0.18 -0.0912 -0.2568 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D16 mock treatment 579518.0 -150000.0 -0.82 758512.0 -28400.0 -0.16 -0.6911 -0.83 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D17 compound treatment 664693.0 -64500.0 -0.35 799575.0 12600.0 0.07 -0.1986 -0.553 3626140 CBKinase1_015677 COc1cccc(c1)N(CC(=O)Nc2ccc(I)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D18 compound treatment 796413.0 67200.0 0.37 804927.0 18000.0 0.1 0.3312 0.8698 3626141 CBKinase1_015678 Cc1cc2nnc(SCC(=O)Nc3sc4CCCc4c3C#N)n2c5ccccc15 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D19 compound treatment 674931.0 -54200.0 -0.3 729805.0 -57100.0 -0.32 -0.4372 -0.9991 3626142 CBKinase1_015679 Cc1cc(C)nc(n1)N(Cc2cccc(c2)[N+](=O)[O-])C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D20 compound treatment 657087.0 -72100.0 -0.39 791475.0 4530.0 0.03 -0.2603 -0.6599 3626143 CBKinase1_015680 CCc1ccc(NC(=O)CSc2nnc(C)n2c3ccccc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D21 compound treatment 641774.0 -87400.0 -0.48 759379.0 -27600.0 -0.16 -0.4473 -0.8913 3626144 CBKinase1_015681 COc1ccc(cc1NC(=O)C(C)N(c2ccccc2)S(=O)(=O)C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D22 compound treatment 627295.0 -102000.0 -0.56 733863.0 -53100.0 -0.3 -0.6049 -0.9577 3626145 CBKinase1_015682 Cc1cccc(NC(=O)CNS(=O)(=O)c2ccc(Br)cc2)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D23 compound treatment 659366.0 -69800.0 -0.38 767869.0 -19100.0 -0.11 -0.3455 -0.8726 3626146 CBKinase1_015683 COC(=O)c1c(NC(=O)c2ccc(cc2)N(C)S(=O)(=O)c3ccccc3)sc4CCCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 D24 compound treatment 739261.0 10100.0 0.06 813906.0 27000.0 0.15 0.1464 0.9057 1299537 CBKinase1_015684 O=c1c2ccccc2nc3c4ccccc4c(NCc5ccccn5)nn13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E01 mock treatment 728509.0 -668.0 0.0 734996.0 -52000.0 -0.29 -0.2096 -0.7159 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E02 mock treatment 534724.0 -194000.0 -1.06 668722.0 -118000.0 -0.67 -1.2219 -0.9748 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E03 compound treatment 679010.0 -50200.0 -0.27 617916.0 -169000.0 -0.95 -0.8674 -0.8749 3626147 CBKinase1_015685 CN(CC(=O)Nc1ccc(cc1)C(F)(F)F)S(=O)(=O)c2ccc(Br)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E04 compound treatment 721773.0 -7400.0 -0.04 667749.0 -119000.0 -0.67 -0.5037 -0.7483 3626148 CBKinase1_015686 CCn1c(SCC(=O)Nc2sc3CC(CCc3c2C#N)C(C)(C)C)nnc1c4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E05 compound treatment 707847.0 -21300.0 -0.12 681072.0 -106000.0 -0.6 -0.5043 -0.8294 3626149 CBKinase1_015687 COc1ccc(NC(=O)CSc2nnc(C)s2)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E06 compound treatment 748574.0 19400.0 0.11 668909.0 -118000.0 -0.67 -0.3956 -0.5872 3626150 CBKinase1_015688 Cc1cc(C)cc(Oc2c(oc3cc(OCC(=O)O)ccc3c2=O)C(F)(F)F)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E07 compound treatment 730294.0 1120.0 0.01 688993.0 -98000.0 -0.55 -0.3861 -0.6993 3626151 CBKinase1_015689 Fc1ccc(NC(=O)CSc2nnc(c3ccco3)c(n2)c4ccco4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E08 compound treatment 674922.0 -54300.0 -0.3 602768.0 -184000.0 -1.04 -0.9435 -0.874 3626152 CBKinase1_015690 Brc1ccc(NC(=O)c2c(NC(=O)CN3CCOCC3)sc4CCCCc24)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E09 mock treatment 727152.0 -2020.0 -0.01 632495.0 -154000.0 -0.87 -0.6234 -0.716 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E10 mock treatment 738793.0 9620.0 0.05 661670.0 -125000.0 -0.71 -0.4622 -0.6527 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E11 compound treatment 697842.0 -31300.0 -0.17 724076.0 -62900.0 -0.35 -0.3715 -0.9442 3626153 CBKinase1_015691 Fc1ccc(CN(Cc2ccco2)C(=O)c3cc4ccccc4oc3=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E12 compound treatment 750410.0 21200.0 0.12 715385.0 -71600.0 -0.4 -0.2032 -0.4843 3626154 CBKinase1_015692 COC(=O)c1cccc(c1)n2c(CCC(=O)O)ccc2c3cccs3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E13 compound treatment 763845.0 34700.0 0.19 714574.0 -72400.0 -0.41 -0.1546 -0.3438 3626155 CBKinase1_015693 Cc1cccc(OCC(=O)Nc2cccc(c2)c3nc4ccccc4[nH]3)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E14 compound treatment 728562.0 -615.0 0.0 691059.0 -95900.0 -0.54 -0.3845 -0.7115 3626156 CBKinase1_015694 Cc1ccc(NC(=O)COc2ccc(CO)cc2Cl)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E15 compound treatment 688976.0 -40200.0 -0.22 684201.0 -103000.0 -0.58 -0.5647 -0.9118 3626157 CBKinase1_015695 Fc1ccc(cc1)n2c(SCC(=O)c3ccccc3)nnc2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E16 compound treatment 694096.0 -35100.0 -0.19 627861.0 -159000.0 -0.9 -0.7695 -0.8392 3626158 CBKinase1_015696 Cc1nnc(SCC(=O)Nc2ccc(Br)cc2F)n1c3cccc(C)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E17 mock treatment 677970.0 -51200.0 -0.28 698395.0 -88600.0 -0.5 -0.5506 -0.9625 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E18 mock treatment 689785.0 -39400.0 -0.22 682470.0 -104000.0 -0.59 -0.5685 -0.9068 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E19 compound treatment 673329.0 -55800.0 -0.3 667703.0 -119000.0 -0.67 -0.6909 -0.9361 3626159 CBKinase1_015697 Fc1ccc(cc1)n2c(SCC(=O)Nc3ccccc3F)nnc2c4ccc(Cl)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E20 compound treatment 637383.0 -91800.0 -0.5 581344.0 -206000.0 -1.16 -1.1738 -0.9297 3626160 CBKinase1_015698 CC(Sc1ncnc2sc(cc12)c3ccccc3)C(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E21 compound treatment 674520.0 -54700.0 -0.3 614789.0 -172000.0 -0.97 -0.8971 -0.8837 3626161 CBKinase1_015699 CCn1c(SCC(=O)Nc2cccc(OC)c2)nnc1c3cccc(C)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E22 compound treatment 574415.0 -155000.0 -0.84 564880.0 -222000.0 -1.25 -1.4825 -0.9817 3626162 CBKinase1_015700 CCOc1ccc(cc1)n2c(SCC(=O)c3ccccc3)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E23 compound treatment 385514.0 -344000.0 -1.88 603834.0 -183000.0 -1.03 -2.0565 -0.9604 3626163 CBKinase1_015701 Cc1cc(Cl)ccc1NC(=O)CNS(=O)(=O)c2ccc(Br)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 E24 compound treatment 464278.0 -265000.0 -1.45 502604.0 -284000.0 -1.6 -2.1559 -0.9987 3626164 CBKinase1_015702 Cc1cccc(C)c1NC(=O)CN(c2cccc(F)c2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F01 mock treatment 562101.0 -167000.0 -0.91 627293.0 -160000.0 -0.9 -1.2813 -1.0 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F02 mock treatment 657397.0 -71800.0 -0.39 663376.0 -124000.0 -0.7 -0.7696 -0.963 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F03 compound treatment 551420.0 -178000.0 -0.97 713729.0 -73200.0 -0.41 -0.978 -0.9274 1179812 CBKinase1_015703 COc1ccccc1NC(=O)Cn2c(=O)oc3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F04 compound treatment 651445.0 -77700.0 -0.42 664679.0 -122000.0 -0.69 -0.7874 -0.9729 3626165 CBKinase1_015704 COC(=O)c1ccccc1NC(=O)COc2ccc(cc2Br)C(C)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F05 compound treatment 689661.0 -39500.0 -0.22 666032.0 -121000.0 -0.68 -0.6345 -0.8875 3626166 CBKinase1_015705 CCn1c(SCC(=O)Nc2ccc(C)c(C)c2)nnc1c3ccncc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F06 compound treatment 631972.0 -97200.0 -0.53 716273.0 -70700.0 -0.4 -0.6569 -0.99 3626167 CBKinase1_015706 CCCn1c(SCC(=O)N2CCOCC2)nnc1c3ccncc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F07 compound treatment 661155.0 -68000.0 -0.37 655502.0 -131000.0 -0.74 -0.7865 -0.949 1208320 CBKinase1_015707 Cc1cc(C)c(C#N)c(SCC(O)CNc2ccc(Cl)cc2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F08 compound treatment 665276.0 -63900.0 -0.35 675743.0 -111000.0 -0.63 -0.6899 -0.9617 1326194 CBKinase1_015708 CCCCC(Nc1ncnc2ccccc12)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F09 mock treatment 730843.0 1670.0 0.01 721826.0 -65100.0 -0.37 -0.2531 -0.6894 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F10 mock treatment 674760.0 -54400.0 -0.3 689678.0 -97300.0 -0.55 -0.5977 -0.9586 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F11 compound treatment 676924.0 -52300.0 -0.29 696522.0 -90400.0 -0.51 -0.5621 -0.9624 3626168 CBKinase1_015709 Cc1nnc(SCC(=O)Nc2cccc(Cl)c2Cl)n1c3ccc(F)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F12 compound treatment 556528.0 -173000.0 -0.94 702816.0 -84100.0 -0.47 -1.0018 -0.9495 3626169 CBKinase1_015710 Cc1cc2nc(SCC(=O)O)nc(C)c2cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F13 compound treatment 706278.0 -22900.0 -0.13 701723.0 -85200.0 -0.48 -0.4281 -0.8624 3626170 CBKinase1_015711 Cc1cc(C)cc(c1)N(CC(=O)Nc2c(C)cc(C)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F14 compound treatment 662218.0 -67000.0 -0.37 715637.0 -71300.0 -0.4 -0.5427 -0.9989 3626171 CBKinase1_015712 Cc1ccc(Nc2nc(N)nc(CSCCO)n2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F15 compound treatment 677155.0 -52000.0 -0.28 660967.0 -126000.0 -0.71 -0.7029 -0.9191 3626172 CBKinase1_015713 OC(=O)CCc1ccc(c2cccs2)n1c3cc(Cl)ccc3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F16 compound treatment 526904.0 -202000.0 -1.1 639007.0 -148000.0 -0.83 -1.3705 -0.9904 3626173 CBKinase1_015714 Cc1ccc(cc1NC(=O)COc2cccc(c2)[N+](=O)[O-])c3nc4ccccc4[nH]3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F17 mock treatment 648832.0 -80300.0 -0.44 670255.0 -117000.0 -0.66 -0.7753 -0.9806 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F18 mock treatment 602811.0 -126000.0 -0.69 697180.0 -89800.0 -0.51 -0.8456 -0.9884 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F19 compound treatment 589512.0 -140000.0 -0.76 600460.0 -186000.0 -1.05 -1.2824 -0.9876 3626174 CBKinase1_015715 Cc1ccc(cc1)S(=O)(=O)NCC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F20 compound treatment 590662.0 -139000.0 -0.76 661000.0 -126000.0 -0.71 -1.0367 -0.9995 3626175 CBKinase1_015716 COc1ccc(Cl)cc1N(CC(=O)N2CCN(CC2)c3cccc(Cl)c3)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F21 compound treatment 632411.0 -96800.0 -0.53 611465.0 -175000.0 -0.99 -1.073 -0.9569 3626176 CBKinase1_015717 CC(C)NS(=O)(=O)c1ccc(OCC(=O)N2CCOCC2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F22 compound treatment 538063.0 -191000.0 -1.04 611364.0 -176000.0 -0.99 -1.4376 -0.9997 3626177 CBKinase1_015718 CCn1c(SCC(=O)Nc2ccc(C)cc2Br)nnc1c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F23 compound treatment 417590.0 -312000.0 -1.7 420841.0 -366000.0 -2.06 -2.662 -0.9954 1848124 CBKinase1_015719 Cc1ccc(NC(=O)CSc2nc3ccccc3s2)cc1[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 F24 compound treatment 511402.0 -218000.0 -1.19 591756.0 -195000.0 -1.1 -1.6187 -0.9992 3626178 CBKinase1_015720 Cc1cc(Br)c(NC(=O)CSc2nc3ccccc3[nH]2)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G01 compound treatment 778348.0 49200.0 0.27 602337.0 -185000.0 -1.04 -0.546 -0.508 3626179 CBKinase1_015721 Oc1nc(CSc2nnc(c3ccccc3)n2C4CCCCC4)nc5ccccc15 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G02 compound treatment 818536.0 89400.0 0.49 813113.0 26200.0 0.15 0.4492 0.8815 3626180 CBKinase1_015722 COc1ccccc1NC(=O)CSc2ncccn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G03 mock treatment 845244.0 116000.0 0.63 811447.0 24500.0 0.14 0.5457 0.8414 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G04 mock treatment 850686.0 122000.0 0.66 777574.0 -9370.0 -0.05 0.4317 0.6487 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G05 compound treatment 794456.0 65300.0 0.36 763501.0 -23400.0 -0.13 0.1586 0.4171 3626181 CBKinase1_015723 Cn1cnnc1SC2CCCCC2NS(=O)(=O)c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G06 compound treatment 776555.0 47400.0 0.26 778882.0 -8070.0 -0.05 0.1508 0.574 3626182 CBKinase1_015724 Cc1nnc(SCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)n1c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G07 compound treatment 785619.0 56400.0 0.31 796710.0 9760.0 0.06 0.2568 0.8204 3626183 CBKinase1_015725 COc1cc(cc(OC)c1OC)c2nnc(SCC(=O)c3ccc(cc3)c4ccccc4)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G08 compound treatment 858278.0 129000.0 0.7 840195.0 53200.0 0.3 0.7106 0.9276 3626184 CBKinase1_015726 COc1ccc(cc1)n2c(SCC(=O)Nc3ccc(Cl)cc3Cl)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G09 compound treatment 811326.0 82100.0 0.45 787592.0 643.0 0.0 0.3197 0.7128 3626185 CBKinase1_015727 COc1cc(NC(=S)NCc2ccco2)c(OC)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G10 compound treatment 818278.0 89100.0 0.49 822360.0 35400.0 0.2 0.4851 0.9226 3626186 CBKinase1_015728 CC(C)c1ccccc1NC(=O)CSc2ncnc3scc(c4ccc(C)cc4)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G11 compound treatment 831107.0 102000.0 0.56 863897.0 76900.0 0.43 0.7002 0.9924 3626187 CBKinase1_015729 COc1cccc(NC(=O)CSC2=C(C#N)C(CC(=O)N2)c3cccc(Br)c3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G12 compound treatment 845600.0 116000.0 0.64 775196.0 -11800.0 -0.07 0.4026 0.63 3626188 CBKinase1_015730 CCn1c(SCC(=O)Nc2ccc(C)c(C)c2)nnc1c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G13 compound treatment 767192.0 38000.0 0.21 734298.0 -52700.0 -0.3 -0.0631 -0.1742 3626189 CBKinase1_015731 O=C(CCN1C(=O)C2C3CC(C=C3)C2C1=O)Oc4cccc5cccnc45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G14 compound treatment 835128.0 106000.0 0.58 775184.0 -11800.0 -0.07 0.3621 0.622 3626190 CBKinase1_015732 COc1ccc(cc1NC(=O)CN(c2ccc(F)cc2)S(=O)(=O)C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G15 compound treatment 811690.0 82500.0 0.45 819040.0 32100.0 0.18 0.4464 0.9197 3626191 CBKinase1_015733 CCc1ccc(NC(=O)CSc2nnc(c3ccc(Cl)cc3)n2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G16 compound treatment 833890.0 105000.0 0.57 765310.0 -21600.0 -0.12 0.318 0.544 1985919 CBKinase1_015734 COc1ccc(cc1)c2ccc(CCC(=O)O)n2c3ccc(cc3)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G17 compound treatment 805621.0 76400.0 0.42 801667.0 14700.0 0.08 0.3538 0.8314 3626192 CBKinase1_015735 COc1cccc(c1)N(CC(=O)Nc2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G18 compound treatment 788574.0 59400.0 0.32 837443.0 50500.0 0.28 0.4305 0.9979 3626193 CBKinase1_015736 CCCn1nnc(NC(=O)COc2ccc(Cl)cc2C)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G19 mock treatment 741141.0 12000.0 0.07 760865.0 -26100.0 -0.15 -0.0578 -0.3591 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G20 mock treatment 713775.0 -15400.0 -0.08 741530.0 -45400.0 -0.26 -0.2405 -0.8925 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G21 compound treatment 740460.0 11300.0 0.06 927579.0 141000.0 0.79 0.604 0.7598 3626194 CBKinase1_015737 COc1ccc(C)cc1N(CC(=O)Nc2c(C)cc(C)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G22 compound treatment 748160.0 19000.0 0.1 728724.0 -58200.0 -0.33 -0.1588 -0.4613 3626195 CBKinase1_015738 COC(=O)c1c(NC(=O)CN(c2cc(C)ccc2C)S(=O)(=O)C)sc3CCCCc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G23 compound treatment 737856.0 8680.0 0.05 650968.0 -136000.0 -0.77 -0.5085 -0.6621 3626196 CBKinase1_015739 COc1cccc(NC(=O)CSc2nnc(c3ccccc3)n2c4ccc(F)cc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 G24 compound treatment 780815.0 51600.0 0.28 692162.0 -94800.0 -0.53 -0.1784 -0.2954 3626197 CBKinase1_015740 NC(=O)C1CCN(CC1)C(=O)CSc2nc3ccccc3s2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H01 compound treatment 741760.0 12600.0 0.07 733811.0 -53100.0 -0.3 -0.1632 -0.5311 3626198 CBKinase1_015741 CCn1c(SCC(=O)Nc2cccc(OC)c2)nnc1c3ccncc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H02 compound treatment 732549.0 3370.0 0.02 830519.0 43600.0 0.25 0.1867 0.758 3626199 CBKinase1_015742 CS(=O)(=O)N(CC(=O)Nc1cc(ccc1Cl)C(F)(F)F)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H03 mock treatment 749087.0 19900.0 0.11 829050.0 42100.0 0.24 0.2447 0.9374 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H04 mock treatment 735080.0 5900.0 0.03 810888.0 23900.0 0.13 0.1182 0.852 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H05 compound treatment 764962.0 35800.0 0.2 827391.0 40400.0 0.23 0.2993 0.9971 3626200 CBKinase1_015743 CCc1ccccc1NC(=O)CN(C)S(=O)(=O)c2c(C)cc(C)cc2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H06 compound treatment 741247.0 12100.0 0.07 899850.0 113000.0 0.64 0.4966 0.7762 3626201 CBKinase1_015744 COc1cc(CO)cc(Cl)c1OCc2cccc(c2)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H07 compound treatment 776888.0 47700.0 0.26 849986.0 63000.0 0.36 0.4354 0.9884 3626202 CBKinase1_015745 COc1ccc(cc1OC)S(=O)(=O)NCC(=O)Nc2cccc(C)c2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H08 compound treatment 800332.0 71200.0 0.39 907683.0 121000.0 0.68 0.7559 0.9647 3626203 CBKinase1_015746 COc1ccc(cc1NC(=O)CN(c2ccccc2Cl)S(=O)(=O)C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H09 compound treatment 764868.0 35700.0 0.19 903681.0 117000.0 0.66 0.603 0.8788 3626204 CBKinase1_015747 COc1ccccc1OCC(=O)Nc2cccc(c2)N(C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H10 compound treatment 1450008.0 721000.0 3.94 855026.0 68100.0 0.38 3.0541 0.7724 3626205 CBKinase1_015748 Cc1cccc(C)c1N(CC(=O)Nc2ccc(I)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H11 compound treatment 795063.0 65900.0 0.36 848298.0 61300.0 0.35 0.4989 0.9998 3626206 CBKinase1_015749 CC(C)c1ccc(NC(=O)CNS(=O)(=O)c2c(C)cc(C)cc2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H12 compound treatment 794532.0 65400.0 0.36 863527.0 76600.0 0.43 0.5575 0.9955 3626207 CBKinase1_015750 CN(c1cccc(NC(=O)COc2ccccc2)c1)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H13 compound treatment 747799.0 18600.0 0.1 848933.0 62000.0 0.35 0.3189 0.8765 3626208 CBKinase1_015751 Cc1cc(C)c(c(C)c1)S(=O)(=O)NCC(=O)Nc2ccc(F)c(Cl)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H14 compound treatment 643991.0 -85200.0 -0.47 747044.0 -39900.0 -0.22 -0.4879 -0.9444 3626209 CBKinase1_015752 [O-][N+](=O)c1cc(ccc1S(=O)CC(=O)OC2CCCCC2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H15 compound treatment 804099.0 74900.0 0.41 886820.0 99900.0 0.56 0.6873 0.9877 3626210 CBKinase1_015753 CN1C(=O)c2ccc(cc2C1=O)C(=O)Nc3ccc(OCC(=O)O)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H16 compound treatment 847566.0 118000.0 0.65 890947.0 104000.0 0.59 0.8715 0.9988 3626211 CBKinase1_015754 Cc1nc(SCC(=O)Nc2ccc(Cl)cc2)c3ccsc3n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H17 compound treatment 868612.0 139000.0 0.76 867817.0 80900.0 0.46 0.8606 0.9699 3626212 CBKinase1_015755 Clc1ccccc1C(=O)Nc2ccccc2C(=O)NCc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H18 compound treatment 765593.0 36400.0 0.2 843441.0 56500.0 0.32 0.3657 0.9743 3626213 CBKinase1_015756 COc1ccc(cc1)n2c(SCC(=O)Nc3ccccc3C(F)(F)F)nnc2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H19 mock treatment 738148.0 8970.0 0.05 846185.0 59200.0 0.33 0.2707 0.8023 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H20 mock treatment 770054.0 40900.0 0.22 820266.0 33300.0 0.19 0.2906 0.9963 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H21 compound treatment 722711.0 -6470.0 -0.04 854254.0 67300.0 0.38 0.2433 0.6386 3626214 CBKinase1_015757 COc1ccc(cc1OC)S(=O)(=O)N(C)CC(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H22 compound treatment 737355.0 8180.0 0.04 802283.0 15300.0 0.09 0.0927 0.9528 3626215 CBKinase1_015758 Cc1ccc(cc1)S(=O)(=O)NCC(=O)Nc2ccc(Br)cc2F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H23 compound treatment 716617.0 -12600.0 -0.07 787699.0 750.0 0.0 -0.0455 -0.6622 1138276 CBKinase1_015759 COc1ccc(Oc2coc3cc(OC(C)C(=O)O)ccc3c2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 H24 compound treatment 756546.0 27400.0 0.15 698191.0 -88800.0 -0.5 -0.2481 -0.4752 3626216 CBKinase1_015760 CC1=CC(C)(C)N2C(=O)C(=O)c3cc(OC(=O)CN4C(=O)c5cccc6cccc(C4=O)c56)cc1c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I01 compound treatment 757496.0 28300.0 0.15 690379.0 -96600.0 -0.54 -0.2756 -0.487 3626217 CBKinase1_015761 CSc1nc2ccccc2n1C(=O)CCCN3C(=O)c4cccc5cccc(C3=O)c45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I02 compound treatment 775579.0 46400.0 0.25 798054.0 11100.0 0.06 0.2234 0.8561 3626218 CBKinase1_015762 CN(CC(=O)Nc1ccc(Cl)cc1C)S(=O)(=O)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I03 compound treatment 777366.0 48200.0 0.26 818312.0 31400.0 0.18 0.311 0.9813 3626219 CBKinase1_015763 Cn1c(SCC(=O)Nc2ccc(cc2)[N+](=O)[O-])nc3ccccc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I04 compound treatment 755698.0 26500.0 0.14 779989.0 -6960.0 -0.04 0.0746 0.4976 3626220 CBKinase1_015764 COc1cccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccc(C)cc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I05 mock treatment 768892.0 39700.0 0.22 832793.0 45800.0 0.26 0.336 0.9962 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I06 mock treatment 736121.0 6940.0 0.04 833766.0 46800.0 0.26 0.2134 0.8005 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I07 compound treatment 741218.0 12000.0 0.07 876551.0 89600.0 0.51 0.4036 0.7925 3626221 CBKinase1_015765 CCC(Sc1nc2ccccc2s1)C(=O)Nc3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I08 compound treatment 778112.0 48900.0 0.27 819468.0 32500.0 0.18 0.3185 0.9831 3626222 CBKinase1_015766 CCCn1nnc(NC(=O)COc2ccc(Br)cc2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I09 compound treatment 788120.0 58900.0 0.32 872610.0 85700.0 0.48 0.569 0.9806 3626223 CBKinase1_015767 COc1ccc(NC(=O)CSc2nc(C)cc(=O)[nH]2)c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I10 compound treatment 734360.0 5180.0 0.03 761551.0 -25400.0 -0.14 -0.0812 -0.5566 3626224 CBKinase1_015768 Cc1cc(C)c(NC(=O)CN(c2cccc(Br)c2)S(=O)(=O)C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I11 compound treatment 809841.0 80700.0 0.44 898705.0 112000.0 0.63 0.7568 0.9847 3626225 CBKinase1_015769 CCOC(=O)c1ccccc1NC(=O)c2cc(Cl)ccc2NC(=O)c3ccc(OC)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I12 compound treatment 741700.0 12500.0 0.07 868903.0 82000.0 0.46 0.375 0.803 3626226 CBKinase1_015770 COc1ccc(cc1NC(=O)CN(c2ccc(C)cc2C)S(=O)(=O)C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I13 compound treatment 719240.0 -9940.0 -0.05 796908.0 9960.0 0.06 0.0013 0.0171 1423515 CBKinase1_015771 CC(=O)Nc1cccc(NC(=O)c2cccc(Cn3cc(Cl)cn3)c2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I14 compound treatment 786226.0 57000.0 0.31 817814.0 30900.0 0.17 0.3433 0.9622 3626227 CBKinase1_015772 Clc1ccccc1n2nnnc2SCC(=O)Nc3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I15 compound treatment 770738.0 41600.0 0.23 838802.0 51900.0 0.29 0.3671 0.9922 3626228 CBKinase1_015773 Cc1ccc(cc1)S(=O)(=O)NCC(=O)Nc2ccccc2F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I16 compound treatment 723719.0 -5460.0 -0.03 793690.0 6740.0 0.04 0.0058 0.1201 3626229 CBKinase1_015774 Cc1nnc(SCC(=O)Nc2ccc(C)c(Cl)c2)n1c3ccc(F)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I17 compound treatment 707384.0 -21800.0 -0.12 898803.0 112000.0 0.63 0.3617 0.5637 3626230 CBKinase1_015775 Cc1cccc(c1)n2c(SCC(=O)Nc3ccccc3)nnc2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I18 compound treatment 720625.0 -8550.0 -0.05 787475.0 526.0 0.0 -0.0309 -0.6608 1860791 CBKinase1_015776 CCc1ccc(OCC(=O)Nc2ccccc2C(=O)N)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I19 compound treatment 692291.0 -36900.0 -0.2 791931.0 4980.0 0.03 -0.1225 -0.6027 3626231 CBKinase1_015777 Clc1ccc(c2nnc(SCC(=O)Nc3sc4CCCCc4c3C#N)[nH]2)c(Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I20 compound treatment 682010.0 -47200.0 -0.26 807416.0 20500.0 0.12 -0.1005 -0.3562 3626232 CBKinase1_015778 Cc1ccc(F)cc1NC(=O)CSc2nc3ccccc3s2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I21 mock treatment 704701.0 -24500.0 -0.13 796998.0 10000.0 0.06 -0.0544 -0.3751 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I22 mock treatment 679363.0 -49800.0 -0.27 773777.0 -13200.0 -0.07 -0.2448 -0.8684 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I23 compound treatment 650826.0 -78400.0 -0.43 751728.0 -35200.0 -0.2 -0.4428 -0.9391 3626233 CBKinase1_015779 Cc1cc(C)c(NC(=O)CN(c2cccc(Cl)c2C)S(=O)(=O)C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 I24 compound treatment 658662.0 -70500.0 -0.38 753340.0 -33600.0 -0.19 -0.4062 -0.9467 1587717 CBKinase1_015780 Clc1ccc(cc1)c2csc3ncnc(NCCN4CCOCC4)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J01 compound treatment 713541.0 -15600.0 -0.09 536831.0 -250000.0 -1.41 -1.0572 -0.7486 3626234 CBKinase1_015781 CC(=O)c1cccc(c1)n2c(CCC(=O)O)ccc2c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J02 compound treatment 723407.0 -5770.0 -0.03 817779.0 30800.0 0.17 0.1006 0.5696 3626235 CBKinase1_015782 OC(=O)CCc1ccc(c2ccc(F)cc2)n1c3ccc(cc3)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J03 compound treatment 709882.0 -19300.0 -0.11 838273.0 51300.0 0.29 0.1301 0.4225 3626236 CBKinase1_015783 CCCn1nnc(NC(=O)COc2ccc(C)cc2C)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J04 compound treatment 687548.0 -41600.0 -0.23 871810.0 84900.0 0.48 0.1775 0.3352 1486646 CBKinase1_015784 NC1=C(C(=O)CN1CCCN2CCOCC2)c3nc4ccccc4s3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J05 mock treatment 732131.0 2950.0 0.02 867779.0 80800.0 0.46 0.3336 0.7317 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J06 mock treatment 726400.0 -2780.0 -0.02 934933.0 148000.0 0.83 0.5791 0.6941 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J07 compound treatment 723457.0 -5720.0 -0.03 833484.0 46500.0 0.26 0.1634 0.6186 1501056 CBKinase1_015785 CC(C)(C)c1ccc(SCC(O)CSc2nc3CCCCc3cc2C#N)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J08 compound treatment 1570761.0 842000.0 4.59 852526.0 65600.0 0.37 3.5103 0.7615 3626237 CBKinase1_015786 CCn1c(SCC(=O)Nc2sc3CCCCc3c2C#N)nnc1c4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J09 compound treatment 726899.0 -2280.0 -0.01 938164.0 151000.0 0.85 0.5939 0.6967 3626238 CBKinase1_015787 Cc1sc2ncnc(NCCOCCO)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J10 compound treatment 752796.0 23600.0 0.13 934509.0 148000.0 0.83 0.6793 0.8071 3626239 CBKinase1_015788 CS(=O)(=O)N(CC(=O)Nc1cc(ccc1Cl)C(F)(F)F)c2cccc(c2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J11 compound treatment 740562.0 11400.0 0.06 844430.0 57500.0 0.32 0.273 0.8277 3626240 CBKinase1_015789 Ic1ccc(NC(=O)CSc2nc3ccccc3s2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J12 compound treatment 727118.0 -2060.0 -0.01 890672.0 104000.0 0.58 0.4054 0.6934 1985642 CBKinase1_015790 NC(=O)C1CCN(CC1)C(=O)CSc2ccccn2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J13 compound treatment 795930.0 66800.0 0.36 973014.0 186000.0 1.05 0.9993 0.9 1601854 CBKinase1_015791 CCOC(=O)c1c(NC(=O)COc2cc(C)ccc2C)sc3CCCc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J14 compound treatment 785005.0 55800.0 0.3 909623.0 123000.0 0.69 0.7044 0.9323 3626241 CBKinase1_015792 CCc1cccc(OCC(=O)Nc2cc(ccc2O)[N+](=O)[O-])c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J15 compound treatment 760055.0 30900.0 0.17 891313.0 104000.0 0.59 0.5352 0.8745 3626242 CBKinase1_015793 Cc1cc(C)c(NC(=O)CN(c2ccc(Cl)cc2C)S(=O)(=O)C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J16 compound treatment 745414.0 16200.0 0.09 878946.0 92000.0 0.52 0.4293 0.8162 3626243 CBKinase1_015794 Cc1ccc(cc1C)N(CC(=O)Nc2ccc(I)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J17 compound treatment 766284.0 37100.0 0.2 872019.0 85100.0 0.48 0.4823 0.9266 3626244 CBKinase1_015795 CCc1cccc(C)c1NC(=O)COc2ccc(NC(=O)C)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J18 compound treatment 715956.0 -13200.0 -0.07 837739.0 50800.0 0.29 0.1514 0.5128 3626245 CBKinase1_015796 COc1ccc(cc1)n2c(SCC(=O)Nc3ccc(Cl)cc3Cl)nnc2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J19 compound treatment 754579.0 25400.0 0.14 866431.0 79500.0 0.45 0.4148 0.8846 1860802 CBKinase1_015797 CCc1ccc(OCC(=O)Nc2cc(OC)ccc2OC)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J20 compound treatment 693593.0 -35600.0 -0.19 813114.0 26200.0 0.15 -0.0331 -0.1357 3626246 CBKinase1_015798 Cc1nnc(SCC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)n1c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J21 mock treatment 687043.0 -42100.0 -0.23 854982.0 68000.0 0.38 0.1085 0.2426 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J22 mock treatment 721180.0 -8000.0 -0.04 771638.0 -15300.0 -0.09 -0.0919 -0.9502 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J23 compound treatment 731285.0 2110.0 0.01 769388.0 -17600.0 -0.1 -0.0618 -0.6207 1438273 CBKinase1_015799 CC(O)C(Nc1ncnc2ccccc12)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 J24 compound treatment 665988.0 -63200.0 -0.34 802780.0 15800.0 0.09 -0.1808 -0.5075 1391065 CBKinase1_015800 OC(=O)C1CCCN1c2ncnc3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K01 compound treatment 788050.0 58900.0 0.32 743129.0 -43800.0 -0.25 0.0526 0.1298 3626247 CBKinase1_015801 COc1cc(NC(=S)NCCN2CCOCC2)c(OC)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K02 compound treatment 726234.0 -2940.0 -0.02 852906.0 66000.0 0.37 0.2515 0.6759 3626248 CBKinase1_015802 CCOC(=O)CSc1nnc(c2ccccc2)n1c3cccc(C)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K03 compound treatment 609709.0 -119000.0 -0.65 789303.0 2350.0 0.01 -0.4518 -0.6926 3626249 CBKinase1_015803 COc1ccc(cc1)C(=O)Nc2ccccc2C(=O)NCCN3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K04 compound treatment 664311.0 -64900.0 -0.35 704887.0 -82100.0 -0.46 -0.5775 -0.9913 3626250 CBKinase1_015804 Cc1ccccc1c2nnc(SCC(=O)Nc3sc4CCCCc4c3C#N)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K05 compound treatment 719048.0 -10100.0 -0.06 758824.0 -28100.0 -0.16 -0.1512 -0.9005 3626251 CBKinase1_015805 CN(CC(=O)Nc1cccc(F)c1)S(=O)(=O)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K06 compound treatment 730565.0 1390.0 0.01 804073.0 17100.0 0.1 0.0736 0.7603 3626252 CBKinase1_015806 Cc1nc2cc(NC(=O)NCc3ccco3)ccc2o1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K07 mock treatment 759131.0 30000.0 0.16 730208.0 -56700.0 -0.32 -0.1105 -0.3076 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K08 mock treatment 750569.0 21400.0 0.12 756668.0 -30300.0 -0.17 -0.0381 -0.1842 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K09 compound treatment 714568.0 -14600.0 -0.08 790157.0 3210.0 0.02 -0.0436 -0.5332 3626253 CBKinase1_015807 COc1ccc(CC(=O)Nc2ccc(NC(=O)c3ccco3)cc2)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K10 compound treatment 676987.0 -52200.0 -0.28 732875.0 -54100.0 -0.3 -0.417 -0.9994 3626254 CBKinase1_015808 CN(CC(=O)Nc1cccc(c1)[N+](=O)[O-])S(=O)(=O)c2c(C)cc(C)cc2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K11 compound treatment 714804.0 -14400.0 -0.08 742791.0 -44200.0 -0.25 -0.2315 -0.887 3626255 CBKinase1_015809 COc1ccc(OC)c(NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K12 compound treatment 697223.0 -32000.0 -0.17 820506.0 33600.0 0.19 0.0104 0.0404 3626256 CBKinase1_015810 COc1cccc(OCC(=O)Nc2ccc(Sc3ccc(cc3)[N+](=O)[O-])cc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K13 compound treatment 664929.0 -64200.0 -0.35 846086.0 59100.0 0.33 -0.0123 -0.0255 3626257 CBKinase1_015811 COc1cccc(NC(=O)CSc2nnc(c3ccccc3)n2c4ccc(Cl)cc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K14 compound treatment 730803.0 1630.0 0.01 777895.0 -9050.0 -0.05 -0.0298 -0.5754 3626258 CBKinase1_015812 Clc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(Cl)c3Cl)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K15 mock treatment 739355.0 10200.0 0.06 842212.0 55300.0 0.31 0.2595 0.8203 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K16 mock treatment 706479.0 -22700.0 -0.12 775304.0 -11600.0 -0.07 -0.134 -0.9558 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K17 compound treatment 699684.0 -29500.0 -0.16 780758.0 -6190.0 -0.03 -0.1385 -0.8408 1863090 CBKinase1_015813 CCn1c(SCC(=O)Nc2ccc(cc2)C(=O)O)nnc1c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K18 compound treatment 772420.0 43200.0 0.24 770861.0 -16100.0 -0.09 0.1028 0.4066 3626259 CBKinase1_015814 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)Nc2c(F)cccc2F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K19 compound treatment 627579.0 -102000.0 -0.55 773872.0 -13100.0 -0.07 -0.4443 -0.7941 3626260 CBKinase1_015815 Fc1ccc(cc1)n2c(SCC(=O)Nc3ccc(Cl)cc3)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K20 compound treatment 617891.0 -111000.0 -0.61 679102.0 -108000.0 -0.61 -0.8594 -1.0 3626261 CBKinase1_015816 COc1cc(CO)ccc1OCC(=O)Nc2ccc(C)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K21 compound treatment 655058.0 -74100.0 -0.4 735131.0 -51800.0 -0.29 -0.4927 -0.9872 3626262 CBKinase1_015817 Cc1cc(I)ccc1NC(=O)CN(c2ccccc2F)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K22 compound treatment 697681.0 -31500.0 -0.17 752714.0 -34200.0 -0.19 -0.258 -0.9983 3626263 CBKinase1_015818 Clc1cc(Cl)c(NC(=O)CSc2nnc3ccccn23)c(Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K23 mock treatment 660087.0 -69100.0 -0.38 692161.0 -94800.0 -0.53 -0.6445 -0.9855 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 K24 mock treatment 625973.0 -103000.0 -0.56 660946.0 -126000.0 -0.71 -0.9006 -0.9934 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L01 compound treatment 751316.0 22100.0 0.12 848878.0 61900.0 0.35 0.3323 0.8996 1443047 CBKinase1_015819 COc1ccc(OC)c(NC(=O)c2c(NCc3ccccn3)sc4CCCCc24)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L02 compound treatment 676284.0 -52900.0 -0.29 780850.0 -6100.0 -0.03 -0.2285 -0.7857 3626264 CBKinase1_015820 COc1ccc(NC(=O)CSc2nnc(C)n2c3ccc(C)c(C)c3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L03 compound treatment 651704.0 -77500.0 -0.42 829139.0 42200.0 0.24 -0.1309 -0.2698 3626265 CBKinase1_015821 Cc1ccc(cc1)N(CC(=O)Nc2c(C)cc(C)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L04 compound treatment 680913.0 -48300.0 -0.26 800381.0 13400.0 0.08 -0.1328 -0.4843 3626266 CBKinase1_015822 Cc1ccc(cc1)S(=O)(=O)NCC(=O)Nc2ccc(F)cc2F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L05 compound treatment 697647.0 -31500.0 -0.17 821330.0 34400.0 0.19 0.0153 0.0591 3626267 CBKinase1_015823 Cc1cc(C)c(NC(=O)CSc2nnc(c3ccncc3)n2C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L06 compound treatment 701334.0 -27800.0 -0.15 793619.0 6670.0 0.04 -0.0809 -0.5166 3626268 CBKinase1_015824 CCc1ccc(cc1)n2c(SCC(=O)Nc3cccc(C)c3)nnc2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L07 mock treatment 673259.0 -55900.0 -0.31 862503.0 75600.0 0.43 0.0853 0.1627 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L08 mock treatment 716490.0 -12700.0 -0.07 839335.0 52400.0 0.3 0.1598 0.5269 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L09 compound treatment 639146.0 -90000.0 -0.49 821087.0 34100.0 0.19 -0.2115 -0.4007 3626269 CBKinase1_015825 COc1ccc(cc1)c2ccc(CCC(=O)O)n2c3ccc(cc3)N(C)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L10 compound treatment 729969.0 792.0 0.0 831956.0 45000.0 0.25 0.1824 0.7191 3626270 CBKinase1_015826 CCc1ccc(OCC(=O)Nc2cccnc2)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L11 compound treatment 718216.0 -11000.0 -0.06 854401.0 67500.0 0.38 0.2265 0.5886 3626271 CBKinase1_015827 Cc1nnc(SCC(=O)Nc2ccc(Br)cc2F)n1c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L12 compound treatment 707686.0 -21500.0 -0.12 909865.0 123000.0 0.69 0.4069 0.5791 3626272 CBKinase1_015828 Cc1ccc(OCC(=O)Nc2cccc(C(=O)O)c2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L13 compound treatment 798594.0 69400.0 0.38 773678.0 -13300.0 -0.07 0.2151 0.5568 3626273 CBKinase1_015829 OC(=O)c1ccc(Cl)cc1NC(=O)COc2ccc(Cl)cc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L14 compound treatment 747843.0 18700.0 0.1 848204.0 61300.0 0.35 0.3162 0.8784 3626274 CBKinase1_015830 CN(CC(=O)Nc1cccc(C)c1C)S(=O)(=O)c2c(C)cc(C)cc2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L15 mock treatment 680140.0 -49000.0 -0.27 816692.0 29700.0 0.17 -0.0708 -0.224 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L16 mock treatment 756449.0 27300.0 0.15 815410.0 28500.0 0.16 0.2187 0.9993 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L17 compound treatment 746983.0 17800.0 0.1 829856.0 42900.0 0.24 0.2397 0.9198 1863093 CBKinase1_015831 Cn1c(SCC(=O)N2c3ccccc3Sc4ccccc24)nnc1c5ccccc5Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L18 compound treatment 660020.0 -69200.0 -0.38 843830.0 56900.0 0.32 -0.0403 -0.0813 3626275 CBKinase1_015832 Cc1cc(I)ccc1NC(=O)CN(c2ccc(Cl)c(Cl)c2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L19 compound treatment 697298.0 -31900.0 -0.17 784923.0 -2030.0 -0.01 -0.1311 -0.7519 3626276 CBKinase1_015833 CC(=O)Nc1ccccc1SCC(=O)Nc2ccc(C)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L20 compound treatment 1782218.0 1050000.0 5.75 2188651.0 1400000.0 7.9 9.6518 0.9878 1716846 CBKinase1_015834 OCCN(CCO)c1nc(nc2sc(cc12)c3ccccc3)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L21 compound treatment 678345.0 -50800.0 -0.28 854719.0 67800.0 0.38 0.0739 0.1565 3626277 CBKinase1_015835 COc1ccc(OCC(=O)Nc2ccccc2C(=O)Nc3ccc(cc3)C(=O)O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L22 compound treatment 696698.0 -32500.0 -0.18 715608.0 -71300.0 -0.4 -0.4097 -0.9323 3626278 CBKinase1_015836 CC(C)c1ccc(OCC(=O)Nc2ccccc2C#N)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L23 mock treatment 739318.0 10100.0 0.06 743375.0 -43600.0 -0.25 -0.1345 -0.5343 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 L24 mock treatment 676154.0 -53000.0 -0.29 814704.0 27800.0 0.16 -0.0941 -0.2859 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M01 compound treatment 889185.0 160000.0 0.87 894133.0 107000.0 0.6 1.0449 0.9838 1985789 CBKinase1_015837 Nc1cc(=O)nc(SCC(=O)N2c3ccccc3Sc4ccccc24)n1CC=C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M02 compound treatment 823949.0 94800.0 0.52 827728.0 40800.0 0.23 0.5284 0.9333 3626279 CBKinase1_015838 Cn1nnc2cc(NC(=O)NCCO)ccc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M03 compound treatment 821910.0 92700.0 0.51 810205.0 23300.0 0.13 0.4507 0.8618 3626280 CBKinase1_015839 O=C(CSc1nnc(c2ccccc2)n1c3ccccc3)N4CCOCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M04 compound treatment 802598.0 73400.0 0.4 779987.0 -6960.0 -0.04 0.2557 0.6349 1222269 CBKinase1_015840 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2ccccn2)c3cc4ccccc4oc3=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M05 compound treatment 778403.0 49200.0 0.27 851016.0 64100.0 0.36 0.4454 0.9894 3626281 CBKinase1_015841 Cc1cccc(OC(=O)C(Cc2ccccc2)N3C(=O)C4C5CCC(C5)C4C3=O)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M06 compound treatment 771518.0 42300.0 0.23 815812.0 28900.0 0.16 0.2785 0.9852 3626282 CBKinase1_015842 CC(C)NS(=O)(=O)c1ccc(OCC(=O)N)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M07 compound treatment 791534.0 62400.0 0.34 884308.0 97400.0 0.55 0.6288 0.9736 3626283 CBKinase1_015843 Clc1cnn(Cc2ccc(o2)C(=O)Nc3ccc(Br)c4cccnc34)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M08 compound treatment 782323.0 53100.0 0.29 851659.0 64700.0 0.36 0.4631 0.9936 3626284 CBKinase1_015844 COc1cccc(NC(=O)CSc2nnc(c3ccc(Cl)cc3)n2c4ccc(F)cc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M09 mock treatment 837476.0 108000.0 0.59 829667.0 42700.0 0.24 0.5883 0.9216 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M10 mock treatment 807928.0 78800.0 0.43 813262.0 26300.0 0.15 0.4089 0.899 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M11 compound treatment 1256906.0 528000.0 2.88 1262883.0 476000.0 2.68 3.9341 0.9994 3626285 CBKinase1_015845 Oc1cc(NC(=O)c2nc[nH]n2)ccc1c3nc4ccccc4o3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M12 compound treatment 786084.0 56900.0 0.31 820503.0 33600.0 0.19 0.3534 0.9717 3626286 CBKinase1_015846 Cc1nnc(SCC(=O)Nc2cc(Cl)cc(Cl)c2)n1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M13 mock treatment 814827.0 85700.0 0.47 852735.0 65800.0 0.37 0.5928 0.9934 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M14 mock treatment 793169.0 64000.0 0.35 791464.0 4520.0 0.03 0.265 0.7566 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M15 compound treatment 782907.0 53700.0 0.29 770206.0 -16700.0 -0.09 0.1407 0.4566 3626287 CBKinase1_015847 Cc1ccc(cc1)S(=O)(=O)NCC(=O)Nc2cccc(c2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M16 compound treatment 781020.0 51800.0 0.28 773508.0 -13400.0 -0.08 0.1466 0.5002 3626288 CBKinase1_015848 [O-][N+](=O)c1cc(ccc1S(=O)CC(=O)Oc2ccccc2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M17 compound treatment 794471.0 65300.0 0.36 803478.0 16500.0 0.09 0.3179 0.8629 3626289 CBKinase1_015849 COC(=O)c1cccc(NC(=O)COc2cccc(c2)[N+](=O)[O-])c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M18 compound treatment 983990.0 255000.0 1.39 957242.0 170000.0 0.96 1.6624 0.9836 3626290 CBKinase1_015850 Cc1ccc(cc1)c2csc3nc4c5ccccc5c(NCCCN6CCOCC6)nn4c(=O)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M19 compound treatment 761916.0 32700.0 0.18 800926.0 14000.0 0.08 0.1821 0.9322 3626291 CBKinase1_015851 Cc1ccc(C)c(NC(=O)CSc2ncnc3sc4CCCc4c23)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M20 compound treatment 763578.0 34400.0 0.19 810954.0 24000.0 0.14 0.2285 0.9871 3626292 CBKinase1_015852 COC(=O)c1ccc(NC(=O)CNS(=O)(=O)c2c(C)cc(C)cc2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M21 compound treatment 745061.0 15900.0 0.09 817876.0 30900.0 0.17 0.1846 0.948 3626293 CBKinase1_015853 Cc1cccc(c1)c2nnc(SCC(=O)Nc3cccc(C)c3C)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M22 compound treatment 762815.0 33600.0 0.18 795582.0 8630.0 0.05 0.1643 0.8646 3626294 CBKinase1_015854 CCN(C(=O)Cn1c(nc2ccccc12)c3nonc3N)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M23 compound treatment 795005.0 65800.0 0.36 829672.0 42700.0 0.24 0.4244 0.981 1985821 CBKinase1_015855 Fc1ccccc1NC(=O)CSc2n[nH]c(n2)c3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 M24 compound treatment 727831.0 -1350.0 -0.01 827265.0 40300.0 0.23 0.1555 0.6839 3626295 CBKinase1_015856 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)Nc2ccc(Br)cc2F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N01 compound treatment 780488.0 51300.0 0.28 876285.0 89300.0 0.5 0.5541 0.9617 1210556 CBKinase1_015857 Cc1cccc(NC(=O)c2ccc(OCC(=O)Nc3ccccc3)cc2)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N02 compound treatment 794019.0 64800.0 0.35 693970.0 -93000.0 -0.52 -0.1202 -0.1901 3626296 CBKinase1_015858 CCn1c(SCC(=O)Nc2ccccc2OC)nnc1c3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N03 compound treatment 786809.0 57600.0 0.31 855767.0 68800.0 0.39 0.4968 0.9946 3626297 CBKinase1_015859 Cc1ccc(NC(=O)CCN2C(=O)c3ccccc3S2(=O)=O)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N04 compound treatment 788217.0 59000.0 0.32 829693.0 42700.0 0.24 0.3983 0.9897 3626298 CBKinase1_015860 OCc1ccc(OCC(=O)Nc2ccccc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N05 compound treatment 765690.0 36500.0 0.2 808540.0 21600.0 0.12 0.227 0.972 3626299 CBKinase1_015861 CCOC(=O)c1c(C)c(C)sc1NC(=O)Cn2cnc3sc(C)c(C)c3c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N06 compound treatment 734637.0 5460.0 0.03 865718.0 78800.0 0.44 0.335 0.7529 3626300 CBKinase1_015862 O=C(COc1ccccc1)Nc2cccc(Oc3ccc4C(=O)NC(=O)c4c3)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N07 compound treatment 741359.0 12200.0 0.07 913997.0 127000.0 0.72 0.5534 0.7695 3626301 CBKinase1_015863 CCc1cc(Br)cc(C)c1NC(=O)CSc2nnc(c3ccncc3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N08 compound treatment 799934.0 70800.0 0.39 859889.0 72900.0 0.41 0.5639 0.9995 3626302 CBKinase1_015864 Cn1c(SCC(=O)Nc2ccc(F)c(Cl)c2)nnc1c3ccncc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N09 mock treatment 821369.0 92200.0 0.5 872288.0 85300.0 0.48 0.696 0.9997 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N10 mock treatment 790220.0 61000.0 0.33 901018.0 114000.0 0.64 0.6903 0.9532 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N11 compound treatment 711324.0 -17900.0 -0.1 785742.0 -1210.0 -0.01 -0.0737 -0.7546 3626303 CBKinase1_015865 CCc1ccc(cc1)n2c(SCC(=O)c3ccc(Cl)cc3)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N12 compound treatment 799421.0 70200.0 0.38 875263.0 88300.0 0.5 0.6232 0.9917 3626304 CBKinase1_015866 CCOc1ccccc1NC(=O)Cn2cnc3ccccc3c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N13 mock treatment 820323.0 91100.0 0.5 902414.0 115000.0 0.65 0.8121 0.9912 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N14 mock treatment 714614.0 -14600.0 -0.08 760141.0 -26800.0 -0.15 -0.1631 -0.955 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N15 compound treatment 753659.0 24500.0 0.13 854320.0 67400.0 0.38 0.363 0.9018 3626305 CBKinase1_015867 CC(=O)Nc1ccc(NC(=O)CN(c2cccc(Br)c2)S(=O)(=O)C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N16 compound treatment 786213.0 57000.0 0.31 853527.0 66600.0 0.38 0.4855 0.9957 1145011 CBKinase1_015868 O=S(=O)(CCSc1nc2CCCCc2cc1C#N)c3nc4ccccc4s3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N17 compound treatment 741222.0 12000.0 0.07 820129.0 33200.0 0.19 0.1787 0.9016 3118938 CBKinase1_015869 O=S(=O)(CCSc1nc2ccccc2s1)c3nc4ccccc4s3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N18 compound treatment 798793.0 69600.0 0.38 847457.0 60500.0 0.34 0.5099 0.9985 3626306 CBKinase1_015870 CCn1c(SCC(=O)Nc2cccc(Cl)c2)nnc1c3ccc(Cl)cc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N19 compound treatment 787806.0 58600.0 0.32 894228.0 107000.0 0.6 0.6539 0.9558 3626307 CBKinase1_015871 OC(COc1ccc(Cl)cc1)CSc2nc(cc(c2C#N)C(F)(F)F)c3cccs3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N20 compound treatment 779878.0 50700.0 0.28 820604.0 33700.0 0.19 0.3299 0.983 3626308 CBKinase1_015872 OCc1ccc(OCc2cccc(c2)C(=O)O)c(Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N21 compound treatment 757047.0 27900.0 0.15 820993.0 34000.0 0.19 0.2433 0.9934 3626309 CBKinase1_015873 Cc1[nH]c2ccccc2c1C(=O)CSc3ncnc4sc(C)c(C)c34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N22 compound treatment 729425.0 248.0 0.0 813428.0 26500.0 0.15 0.1065 0.7135 3626310 CBKinase1_015874 Clc1ccc(SCC(=O)Nc2cccc(c2)c3nnc(o3)c4ccco4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N23 compound treatment 760758.0 31600.0 0.17 793821.0 6870.0 0.04 0.1493 0.8449 3626311 CBKinase1_015875 CCc1ccc(cc1)n2c(C)nnc2SCC(=O)Nc3ccc(Cl)cc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 N24 compound treatment 797190.0 68000.0 0.37 853561.0 66600.0 0.38 0.528 1.0 3626312 CBKinase1_015876 COc1cc(ccc1OC(=O)C)C(=O)Nc2ccc(OCC(=O)O)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O01 compound treatment 785101.0 55900.0 0.31 823329.0 36400.0 0.21 0.3609 0.9812 3626313 CBKinase1_015877 OCCNC(=O)c1cc(Cl)ccc1NC(=O)c2ccc(Cl)cc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O02 compound treatment 881780.0 153000.0 0.83 730065.0 -56900.0 -0.32 0.3624 0.406 3626314 CBKinase1_015878 CCOc1ccc2nc(SCC(=O)O)nc(C)c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O03 compound treatment 813137.0 84000.0 0.46 761898.0 -25100.0 -0.14 0.2243 0.4676 3120769 CBKinase1_015879 Cc1cc(C)c2c(nn3c(C)c(CCC(=O)O)c(C)nc23)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O04 compound treatment 795827.0 66700.0 0.36 776866.0 -10100.0 -0.06 0.2171 0.5895 3626315 CBKinase1_015880 Cc1nnc(SCC(=O)Nc2ccc(Cl)cc2)n1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O05 compound treatment 781702.0 52500.0 0.29 774364.0 -12600.0 -0.07 0.1526 0.5166 3626316 CBKinase1_015881 CN(CC(=O)Nc1ccc(NC(=O)C)cc1)S(=O)(=O)c2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O06 compound treatment 756313.0 27100.0 0.15 784564.0 -2380.0 -0.01 0.0953 0.6403 3626317 CBKinase1_015882 OC(=O)CCc1ccc(c2ccc(Cl)cc2)n1c3ccc(cc3)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O07 compound treatment 793402.0 64200.0 0.35 854058.0 67100.0 0.38 0.5154 0.9993 3626318 CBKinase1_015883 OC(=O)c1cc(Br)ccc1NC(=O)c2ccc(NC(=O)CSc3ccccc3)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O08 compound treatment 814036.0 84900.0 0.46 781709.0 -5240.0 -0.03 0.3067 0.6607 3626319 CBKinase1_015884 Cn1c(SCC(=O)Nc2ccc(cc2)C(=O)O)nnc1c3ccc(Cl)cc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O09 compound treatment 793138.0 64000.0 0.35 839273.0 52300.0 0.29 0.4555 0.9965 3626320 CBKinase1_015885 COc1ccc(NC(=O)CNS(=O)(=O)c2ccccc2)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O10 compound treatment 758788.0 29600.0 0.16 797641.0 10700.0 0.06 0.1569 0.9096 3626321 CBKinase1_015886 FC(F)(F)c1ccccc1NC(=O)CSc2nnc(c3ccc(Cl)cc3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O11 mock treatment 799049.0 69900.0 0.38 824897.0 37900.0 0.21 0.421 0.9626 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O12 mock treatment 816129.0 87000.0 0.47 806024.0 19100.0 0.11 0.4117 0.8458 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O13 compound treatment 809253.0 80100.0 0.44 872247.0 85300.0 0.48 0.6491 0.9989 1296009 CBKinase1_015887 Cc1sc2ncn(CC(=O)Nc3ccc(F)cc3)c(=O)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O14 compound treatment 790271.0 61100.0 0.33 821140.0 34200.0 0.19 0.3721 0.966 3626322 CBKinase1_015888 Cc1ccc(cc1C)n2c(SCC(=O)Nc3cccc(C)c3C)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O15 compound treatment 795625.0 66400.0 0.36 848795.0 61800.0 0.35 0.503 0.9998 3626323 CBKinase1_015889 Cc1cccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccc(C)c(C)c4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O16 compound treatment 823364.0 94200.0 0.51 797313.0 10400.0 0.06 0.4049 0.7824 3626324 CBKinase1_015890 CCc1ccc(cc1)n2c(SCC(=O)Nc3ccc(F)cc3)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O17 compound treatment 821411.0 92200.0 0.5 790668.0 3720.0 0.02 0.3709 0.7359 3626325 CBKinase1_015891 Cc1nnc(SCC(=O)Nc2ccc(C)cc2Br)n1c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O18 compound treatment 782081.0 52900.0 0.29 807587.0 20600.0 0.12 0.2865 0.9201 1693247 CBKinase1_015892 Cc1cc(C)c(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3cc(C)nc(C)n3)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O19 compound treatment 788020.0 58800.0 0.32 734257.0 -52700.0 -0.3 0.0172 0.0392 3626326 CBKinase1_015893 COc1ccc(OC)c(c1)S(=O)(=O)Nc2ccc(NC(=O)C)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O20 compound treatment 768433.0 39300.0 0.21 835757.0 48800.0 0.28 0.3461 0.9924 3626327 CBKinase1_015894 CCOc1ccccc1NC(=O)CSc2ncnc3sc(C)c(C)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O21 compound treatment 780835.0 51700.0 0.28 777487.0 -9460.0 -0.05 0.1617 0.5634 3626328 CBKinase1_015895 Cc1ccc(cc1)S(=O)(=O)NCC(=O)Nc2ccc(C)c(Cl)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O22 compound treatment 784791.0 55600.0 0.3 759441.0 -27500.0 -0.16 0.1051 0.3082 3626329 CBKinase1_015896 COc1cc(CO)cc(Cl)c1OCc2cccc(c2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O23 compound treatment 739128.0 9950.0 0.05 737786.0 -49200.0 -0.28 -0.1575 -0.5578 1341818 CBKinase1_015897 CCc1ccccc1NC(=O)Cn2cnc3scc(c4ccc(OC)cc4)c3c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 O24 compound treatment 751152.0 22000.0 0.12 770425.0 -16500.0 -0.09 0.019 0.125 3626330 CBKinase1_015898 Cc1sc2ncnc(SCC(=O)Nc3ccccc3)c2c1c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P01 compound treatment 779569.0 50400.0 0.28 750259.0 -36700.0 -0.21 0.0483 0.1404 1722638 CBKinase1_015899 NC(=O)CCC(Nc1ncnc2ccccc12)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P02 compound treatment 773916.0 44700.0 0.24 776149.0 -10800.0 -0.06 0.1297 0.5151 3626331 CBKinase1_015900 Fc1ccc(cc1)n2c(SCC(=O)c3ccccc3)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P03 compound treatment 723955.0 -5220.0 -0.03 852164.0 65200.0 0.37 0.2398 0.6503 3626332 CBKinase1_015901 COc1cccc(NC(=O)CSc2nnc(c3ccc(Cl)cc3)n2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P04 compound treatment 788753.0 59600.0 0.33 770709.0 -16200.0 -0.09 0.1653 0.4891 3626333 CBKinase1_015902 COc1ccc(OC)c(NS(=O)(=O)c2cc(OC)ccc2OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P05 compound treatment 730980.0 1800.0 0.01 822842.0 35900.0 0.2 0.15 0.7406 3626334 CBKinase1_015903 COc1ccc(Cl)cc1NC(=O)CSc2nnc(c3cccc(C)c3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P06 compound treatment 719253.0 -9920.0 -0.05 836638.0 49700.0 0.28 0.1597 0.5599 3626335 CBKinase1_015904 COc1ccc(cc1)n2c(SCC(=O)N3CCOCC3)nnc2c4ccc(Cl)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P07 compound treatment 708682.0 -20500.0 -0.11 1050248.0 263000.0 1.48 0.9703 0.6519 3626336 CBKinase1_015905 Cc1ccc(C)c(NC(=O)CSc2nnc(c3ccncc3)n2c4ccc(F)cc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P08 compound treatment 763023.0 33800.0 0.18 819509.0 32600.0 0.18 0.2604 1.0 3626337 CBKinase1_015906 Brc1ccc(cc1)c2csc3ncnc(SCC(=O)Nc4ccccc4)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P09 compound treatment 663313.0 -65900.0 -0.36 718762.0 -68200.0 -0.38 -0.526 -0.9994 3626338 CBKinase1_015907 Oc1ccc(cc1Nc2ncnc3ccccc23)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P10 compound treatment 792399.0 63200.0 0.35 830856.0 43900.0 0.25 0.4191 0.9867 3626339 CBKinase1_015908 COc1ccc(C)cc1N(CC(=O)N2CCN(CC2)c3cc(Cl)ccc3C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P11 mock treatment 711430.0 -17700.0 -0.1 906138.0 119000.0 0.67 0.4065 0.5989 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P12 mock treatment 694074.0 -35100.0 -0.19 795881.0 8930.0 0.05 -0.0999 -0.5042 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P13 compound treatment 625695.0 -103000.0 -0.56 815384.0 28400.0 0.16 -0.2862 -0.4873 3626340 CBKinase1_015909 CC(=O)c1cccc(NC(=O)CNS(=O)(=O)c2ccc(Cl)cc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P14 compound treatment 729589.0 412.0 0.0 922102.0 135000.0 0.76 0.5403 0.7092 3626341 CBKinase1_015910 [O-][N+](=O)c1ccc(cc1NCc2cccnc2)N3CCN(CC3)C(=O)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P15 compound treatment 763634.0 34500.0 0.19 850266.0 63300.0 0.36 0.3854 0.9553 3626342 CBKinase1_015911 Cn1c(SCC(=O)Nc2ccc(Br)cc2Cl)nnc1c3ccncc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P16 compound treatment 809776.0 80600.0 0.44 850347.0 63400.0 0.36 0.5638 0.9947 3626343 CBKinase1_015912 OCc1ccc(OCc2cccc(c2)C(=O)O)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P17 compound treatment 821281.0 92100.0 0.5 867135.0 80200.0 0.45 0.6752 0.9986 3626344 CBKinase1_015913 COc1ccccc1NC(=O)CNS(=O)(=O)c2ccc(C)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P18 compound treatment 860124.0 131000.0 0.71 880596.0 93600.0 0.53 0.8788 0.9889 3626345 CBKinase1_015914 COC(=O)COc1c(Br)cc(cc1OC)C2C3=C(CCCC3=O)NC4=C2C(=O)CCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P19 compound treatment 801064.0 71900.0 0.39 832005.0 45100.0 0.25 0.4571 0.9778 3626346 CBKinase1_015915 COC(=O)c1cc(cc(c1)n2c(C)cc(C(=O)CSc3nc(C)cc(C)c3C#N)c2C)C(=O)OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P20 compound treatment 788623.0 59400.0 0.32 830031.0 43100.0 0.24 0.4012 0.9898 3626347 CBKinase1_015916 CC(=O)Nc1ccc(OCC(=O)Nc2ccc(Cl)c(Cl)c2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P21 compound treatment 782290.0 53100.0 0.29 812383.0 25400.0 0.14 0.3064 0.9472 1978169 CBKinase1_015917 OC(CSc1nc(cc(c1C#N)C(F)(F)F)c2cccs2)CN3CCSCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P22 compound treatment 766792.0 37600.0 0.21 793625.0 6680.0 0.04 0.1718 0.823 3626348 CBKinase1_015918 Cc1ccc(cc1C)n2c(SCC(=O)Nc3ccccc3F)nnc2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P23 compound treatment 798038.0 68900.0 0.38 806781.0 19800.0 0.11 0.3449 0.8793 3118990 CBKinase1_015919 COc1ccc(cc1)C(=O)Nc2ccc3C(=O)N(CCC(=O)O)C(=O)c3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2373 P24 compound treatment 716951.0 -12200.0 -0.07 837347.0 50400.0 0.28 0.1537 0.5266 3626349 CBKinase1_015920 COC(=O)C(C)Sc1ncnc2scc(c3ccc(Cl)cc3)c12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A01 compound treatment 910099.0 11100.0 0.06 902945.0 18500.0 0.1 0.1167 0.9671 3626350 CBKinase1_015921 CC(C)OCCCNc1ncnc2sc3CC(C)CCc3c12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A02 compound treatment 968986.0 70000.0 0.38 971216.0 86800.0 0.49 0.6161 0.9926 3626351 CBKinase1_015922 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)Nc2ccc(cc2)C(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A03 compound treatment 877224.0 -21700.0 -0.12 947138.0 62700.0 0.35 0.1659 0.4451 3626352 CBKinase1_015923 Cc1cc(O)nc(SCC(=O)N2CCC(CC2)C(=O)N)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A04 compound treatment 778911.0 -120000.0 -0.66 868696.0 -15800.0 -0.09 -0.5263 -0.7957 3626353 CBKinase1_015924 CCc1ccc(NC(=O)Cn2cnc3ccccc3c2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A05 compound treatment 932142.0 33200.0 0.18 893967.0 9510.0 0.05 0.166 0.8787 1257072 CBKinase1_015925 Cc1[nH]c2ccccc2c1C(=O)CSc3nc4sc5CCCc5c4c(=O)n3CC=C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A06 compound treatment 960089.0 61100.0 0.33 920443.0 36000.0 0.2 0.3794 0.9715 3626354 CBKinase1_015926 OCCOCCNc1ncnc2sc(cc12)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A07 compound treatment 992554.0 93600.0 0.51 918941.0 34500.0 0.19 0.4987 0.9123 3626355 CBKinase1_015927 OC(=O)CCS(=O)(=O)c1cccc2cccnc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A08 compound treatment 981966.0 83000.0 0.45 903109.0 18700.0 0.11 0.3948 0.8486 3626356 CBKinase1_015928 CS(=O)(=O)N(CC(=O)Nc1ccccc1c2ccccc2)c3ccc(F)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A09 compound treatment 1013875.0 115000.0 0.63 833544.0 -50900.0 -0.29 0.2407 0.3489 3626357 CBKinase1_015929 Oc1ccc(cc1)n2nnnc2SCC(=O)Nc3ccc(F)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A10 compound treatment 923723.0 24800.0 0.14 914178.0 29700.0 0.17 0.214 0.9943 3626358 CBKinase1_015930 Cc1nnc(SCC(=O)Nc2cccc(c2)C(F)(F)F)n1c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A11 compound treatment 830584.0 -68400.0 -0.37 857882.0 -26600.0 -0.15 -0.3699 -0.9196 1168824 CBKinase1_015931 COc1ccccc1NC(=O)c2ccc(OCC(=O)Nc3cc(Cl)cc(Cl)c3)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A12 compound treatment 934550.0 35600.0 0.19 723085.0 -161000.0 -0.91 -0.5058 -0.5438 3626359 CBKinase1_015932 CCOc1ccc(cc1)n2c(C)nnc2SCC(=O)Nc3ccc(Br)cc3F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A13 mock treatment 1014432.0 115000.0 0.63 1015168.0 131000.0 0.74 0.9667 0.997 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A14 mock treatment 974014.0 75100.0 0.41 1047253.0 163000.0 0.92 0.9386 0.934 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A15 compound treatment 981909.0 82900.0 0.45 876818.0 -7640.0 -0.04 0.2898 0.637 3626360 CBKinase1_015933 OCc1ccc(OCC(=O)Nc2ccc(F)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A16 compound treatment 980855.0 81900.0 0.45 945494.0 61000.0 0.34 0.5594 0.9916 3626361 CBKinase1_015934 COc1ccc(cc1NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A17 compound treatment 753593.0 -145000.0 -0.79 869521.0 -14900.0 -0.08 -0.6207 -0.7778 3626362 CBKinase1_015935 OCc1cc(Cl)c(OCC(=O)O)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A18 compound treatment 861351.0 -37600.0 -0.21 983375.0 98900.0 0.56 0.249 0.4192 3626363 CBKinase1_015936 Cc1cc(Br)ccc1NC(=O)CCN2C(=O)c3ccccc3S2(=O)=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A19 compound treatment 1048845.0 150000.0 0.82 1892086.0 1010000.0 5.68 4.5946 0.8007 3626364 CBKinase1_015937 Cn1c(SCC(=O)Nc2sc3CCCCc3c2C#N)nnc1c4ccc(Cl)cc4Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A20 compound treatment 888868.0 -10100.0 -0.06 841544.0 -42900.0 -0.24 -0.21 -0.8465 3626365 CBKinase1_015938 COC(=O)c1ccc(cc1)C2N(Cc3ccncc3)C(=O)C(=C2C(=O)c4cc5ccccc5o4)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A21 compound treatment 642986.0 -256000.0 -1.4 892341.0 7880.0 0.04 -0.9568 -0.6843 1381040 CBKinase1_015939 Clc1cc(Cl)cc(NC(=O)COc2ccc(cc2)C(=O)Nc3ccccc3Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A22 compound treatment 949436.0 50500.0 0.28 832935.0 -51500.0 -0.29 -0.0105 -0.0262 3626366 CBKinase1_015940 CCn1c(SCC(=O)Nc2ccc(cc2C)[N+](=O)[O-])nnc1c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A23 compound treatment 889003.0 -9960.0 -0.05 909914.0 25500.0 0.14 0.063 0.4107 3626367 CBKinase1_015941 COc1ccc(cc1)n2c(SCC(=O)Nc3ccc(C)c(C)c3)nnc2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 A24 compound treatment 875691.0 -23300.0 -0.13 872314.0 -12100.0 -0.07 -0.1382 -0.9579 3626368 CBKinase1_015942 CC(=O)c1ccccc1OC(=O)COc2ccc(cc2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B01 compound treatment 869999.0 -29000.0 -0.16 945143.0 60700.0 0.34 0.1301 0.3451 3626369 CBKinase1_015943 COc1ccc(cc1OC)c2csc3ncn(CC(=O)N)c(=O)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B02 compound treatment 888698.0 -10300.0 -0.06 967575.0 83100.0 0.47 0.2916 0.6181 1280380 CBKinase1_015944 Fc1cc(Br)ccc1NC(=O)CN2C(=O)c3ccccc3S2(=O)=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B03 compound treatment 783033.0 -116000.0 -0.63 924074.0 39600.0 0.22 -0.2896 -0.4316 3626370 CBKinase1_015945 CCOC(=O)C(C)Sc1nc2ccc(I)cc2c(=O)n1c3ccccc3OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B04 compound treatment 928030.0 29100.0 0.16 901601.0 17100.0 0.1 0.1805 0.9717 3626371 CBKinase1_015946 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)Nc2cc(ccc2Cl)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B05 compound treatment 915981.0 17000.0 0.09 932149.0 47700.0 0.27 0.2558 0.8993 3626372 CBKinase1_015947 COc1ccc(NC(=O)c2ccc(OC(C)C(=O)O)cc2)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B06 compound treatment 930945.0 32000.0 0.17 943198.0 58700.0 0.33 0.3576 0.9553 3626373 CBKinase1_015948 CN(CC(=O)Nc1cccc2ccccc12)S(=O)(=O)c3ccc(F)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B07 compound treatment 915732.0 16800.0 0.09 999532.0 115000.0 0.65 0.5234 0.799 1415824 CBKinase1_015949 CCc1ccccc1NC(=O)COc2ccc3c(=O)c(Oc4ccccc4Cl)coc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B08 compound treatment 910955.0 12000.0 0.07 977309.0 92900.0 0.52 0.4164 0.7894 3626374 CBKinase1_015950 COc1ccc(Nc2nc(N)nc(CSc3nc4cc(OC)ccc4s3)n2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B09 compound treatment 576536.0 -322000.0 -1.76 632819.0 -252000.0 -1.42 -2.2476 -0.9943 3626375 CBKinase1_015951 Cc1ccnc(NC(c2cccc(Cl)c2)c3ccc4ccc(C)nc4c3O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B10 compound treatment 843635.0 -55300.0 -0.3 920022.0 35600.0 0.2 -0.0718 -0.1982 3626376 CBKinase1_015952 CCc1cccc(C)c1NC(=O)CNS(=O)(=O)c2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B11 compound treatment 937823.0 38900.0 0.21 890429.0 5970.0 0.03 0.1738 0.8091 3626377 CBKinase1_015953 COc1ccc(NC(=O)c2ccccc2OCC(=O)Nc3cccc(C)c3C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B12 compound treatment 989813.0 90900.0 0.5 932819.0 48400.0 0.27 0.5435 0.9602 3626378 CBKinase1_015954 CCn1c(SCC(=O)Nc2cccc(Cl)c2)nnc1c3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B13 mock treatment 887341.0 -11600.0 -0.06 886265.0 1810.0 0.01 -0.0377 -0.5861 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B14 mock treatment 841598.0 -57400.0 -0.31 972386.0 87900.0 0.5 0.129 0.22 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B15 compound treatment 950511.0 51600.0 0.28 895770.0 11300.0 0.06 0.2441 0.8459 3626379 CBKinase1_015955 [O-][N+](=O)c1ccc(NC(=O)CN2CCOCC2)c(c1)C(=O)Nc3ccccc3F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B16 compound treatment 975084.0 76100.0 0.42 898759.0 14300.0 0.08 0.3509 0.8288 3626380 CBKinase1_015956 Cc1ccc(cc1)C(=O)Nc2ccc(OCC(=O)O)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B17 compound treatment 895835.0 -3130.0 -0.02 883604.0 -854.0 0.0 -0.0155 -0.8726 3626381 CBKinase1_015957 COc1ccc(CCNC(=O)Nc2cccc3ccccc23)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B18 compound treatment 1022017.0 123000.0 0.67 984816.0 100000.0 0.57 0.875 0.9963 3626382 CBKinase1_015958 Cc1cc(C)c(NC(=O)CN(c2ccc(I)cc2)S(=O)(=O)C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B19 compound treatment 928799.0 29800.0 0.16 941355.0 56900.0 0.32 0.342 0.9507 3626383 CBKinase1_015959 COC(=O)c1ccc(cc1)n2c(CCC(=O)O)ccc2c3ccc(OC)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B20 compound treatment 879195.0 -19800.0 -0.11 986759.0 102000.0 0.58 0.3314 0.565 3626384 CBKinase1_015960 O=C(CCN1C(=O)c2ccccc2S1(=O)=O)Nc3ccc4OCCOc4c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B21 compound treatment 973249.0 74300.0 0.41 986766.0 102000.0 0.58 0.6945 0.9852 3626385 CBKinase1_015961 Cc1ccc(NC(=O)CSc2nc3sc4CCCc4c3c(=O)n2c5ccccc5)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B22 compound treatment 897631.0 -1330.0 -0.01 963518.0 79100.0 0.45 0.31 0.6955 3626386 CBKinase1_015962 CCOc1ccc(NC(=O)CSc2nnc(c3ccc(Cl)cc3)n2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B23 compound treatment 1070281.0 171000.0 0.94 793591.0 -90900.0 -0.51 0.2992 0.2806 3626387 CBKinase1_015963 COc1ccc(cc1)n2c(C)nnc2SCC(=O)Nc3ccc(F)c(Cl)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 B24 compound treatment 1004863.0 106000.0 0.58 666510.0 -218000.0 -1.23 -0.4598 -0.3387 3626388 CBKinase1_015964 COc1cccc(NC(=O)c2cc(ccc2NCc3cccnc3)[N+](=O)[O-])c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C01 compound treatment 922788.0 23800.0 0.13 901217.0 16800.0 0.09 0.1588 0.9876 3626389 CBKinase1_015965 COc1ccc(cc1NC(=O)CN(c2ccc(Cl)cc2C)S(=O)(=O)C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C02 compound treatment 854529.0 -44400.0 -0.24 887266.0 2810.0 0.02 -0.1603 -0.6596 3626390 CBKinase1_015966 COc1ccc(cc1)c2ccc(CCC(=O)O)n2c3cc(Cl)ccc3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C03 compound treatment 751079.0 -148000.0 -0.81 867509.0 -16900.0 -0.1 -0.6384 -0.7853 3626391 CBKinase1_015967 OC(=O)c1cccc(NC(=O)c2ccc(CN3C(=O)c4ccccc4C3=O)cc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C04 compound treatment 822248.0 -76700.0 -0.42 840066.0 -44400.0 -0.25 -0.4731 -0.9697 3626392 CBKinase1_015968 CC(=O)Nc1ccc(NC(=O)CN(c2ccc(I)cc2)S(=O)(=O)C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C05 compound treatment 909511.0 10600.0 0.06 968995.0 84500.0 0.48 0.3777 0.7869 1573381 CBKinase1_015969 Cc1ccc(NC(=O)c2ccc(OC(=O)CCN3C(=O)c4ccccc4C3=O)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C06 compound treatment 819679.0 -79300.0 -0.43 884367.0 -91.3 0.0 -0.3064 -0.7079 3626393 CBKinase1_015970 CCOC(=O)c1cnc2c(cccc2c1NCCO)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C07 compound treatment 965108.0 66100.0 0.36 942709.0 58300.0 0.33 0.4875 0.9989 3626394 CBKinase1_015971 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)Nc2cccc(c2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C08 compound treatment 1014613.0 116000.0 0.63 924253.0 39800.0 0.22 0.6051 0.903 3626395 CBKinase1_015972 Clc1ccc(NC(=O)Cn2cnc3ccccc3c2=O)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C09 compound treatment 878561.0 -20400.0 -0.11 814155.0 -70300.0 -0.4 -0.3589 -0.8721 3626396 CBKinase1_015973 CC(=O)Nc1ccc(NC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C10 compound treatment 962177.0 63200.0 0.35 901185.0 16700.0 0.09 0.3107 0.8684 3626397 CBKinase1_015974 Cc1cc(C)c(c(C)c1)S(=O)(=O)NCC(=O)Nc2ccc(I)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C11 mock treatment 730792.0 -168000.0 -0.92 936002.0 51500.0 0.29 -0.4438 -0.4608 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C12 mock treatment 967420.0 68500.0 0.37 874424.0 -10000.0 -0.06 0.2243 0.5934 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C13 compound treatment 922885.0 23900.0 0.13 868437.0 -16000.0 -0.09 0.0285 0.1795 3626398 CBKinase1_015975 COc1cc(CO)cc(I)c1OCc2cccc(c2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C14 compound treatment 884077.0 -14900.0 -0.08 874148.0 -10300.0 -0.06 -0.0985 -0.9865 3626399 CBKinase1_015976 Cc1cc(C)c(C#N)c(SCC(O)CSc2ccc(Cl)cc2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C15 mock treatment 888963.0 -10000.0 -0.05 847722.0 -36700.0 -0.21 -0.185 -0.864 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C16 mock treatment 870347.0 -28600.0 -0.16 953366.0 68900.0 0.39 0.1642 0.3922 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C17 compound treatment 951452.0 52500.0 0.29 879607.0 -4850.0 -0.03 0.1833 0.6367 3626400 CBKinase1_015977 Cc1sc2ncnc(SCC(=O)c3ccc4ccccc4c3)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C18 compound treatment 977562.0 78600.0 0.43 938834.0 54400.0 0.31 0.5202 0.9864 3626401 CBKinase1_015978 Cc1ccc(cc1)N(CC(=O)Nc2ccccc2c3ccccc3)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C19 compound treatment 871905.0 -27100.0 -0.15 1000865.0 116000.0 0.66 0.3595 0.5345 3626402 CBKinase1_015979 Cc1ccc(cc1)S(=O)(=O)NCC(=O)Nc2ccc(I)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C20 compound treatment 775486.0 -123000.0 -0.67 887864.0 3410.0 0.02 -0.4631 -0.6867 3626403 CBKinase1_015980 CC(C)OC(=O)c1sc2ncn(CC(=O)Nc3ccc(C)cc3)c(=O)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C21 compound treatment 971330.0 72400.0 0.4 918955.0 34500.0 0.19 0.4169 0.9467 3626404 CBKinase1_015981 O=C(CSc1ncccn1)Nc2sc3CCCCc3c2C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C22 compound treatment 816435.0 -82500.0 -0.45 1013164.0 129000.0 0.73 0.1944 0.2276 3626405 CBKinase1_015982 CCOc1ccc(NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)c3cccs3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C23 compound treatment 803209.0 -95800.0 -0.52 844371.0 -40100.0 -0.23 -0.5294 -0.9296 3626406 CBKinase1_015983 CCc1cccc(C)c1NC(=O)CSc2nnc(c3ccncc3)n2c4ccc(C)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 C24 compound treatment 863419.0 -35500.0 -0.19 771581.0 -113000.0 -0.64 -0.5871 -0.8826 3626407 CBKinase1_015984 COc1ccc(OC)c(NC(=O)Cn2cnc3sc(C)c(c4ccccc4)c3c2=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D01 compound treatment 903164.0 4200.0 0.02 982718.0 98300.0 0.55 0.4078 0.7358 3626408 CBKinase1_015985 Cc1ccc(cc1)n2c(SCC(=O)Nc3c(Cl)cccc3Cl)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D02 compound treatment 779833.0 -119000.0 -0.65 874150.0 -10300.0 -0.06 -0.501 -0.7672 3626409 CBKinase1_015986 COC(=O)c1c(C)c(C)sc1NC(=O)CSc2ncnc3sc(C)c(C)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D03 compound treatment 795605.0 -103000.0 -0.56 804551.0 -79900.0 -0.45 -0.7175 -0.9938 3626410 CBKinase1_015987 Cc1ccc(NC(=O)CSc2nnc([nH]2)c3ccncc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D04 compound treatment 781219.0 -118000.0 -0.64 848367.0 -36100.0 -0.2 -0.5984 -0.8875 3626411 CBKinase1_015988 Cc1ccc(cc1)S(=O)(=O)NCC(=O)Nc2ccc(cc2)C(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D05 compound treatment 922053.0 23100.0 0.13 940924.0 56500.0 0.32 0.3142 0.9178 3626412 CBKinase1_015989 CN(CC(=O)O)S(=O)(=O)c1c(C)cc(C)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D06 compound treatment 852277.0 -46700.0 -0.25 847829.0 -36600.0 -0.21 -0.3262 -0.9945 3626413 CBKinase1_015990 OC(=O)c1cc(Br)ccc1NC(=O)COc2ccc(Cl)cc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D07 compound treatment 859970.0 -39000.0 -0.21 875640.0 -8820.0 -0.05 -0.1857 -0.8494 3626414 CBKinase1_015991 COc1cccc(c1)N(CC(=O)Nc2c(C)cc(C)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D08 compound treatment 923088.0 24100.0 0.13 921742.0 37300.0 0.21 0.2417 0.9747 3626415 CBKinase1_015992 COC(=O)COc1cccc(NC(=O)c2cccc(C)c2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D09 compound treatment 974891.0 75900.0 0.41 816083.0 -68400.0 -0.39 0.0206 0.0364 3626416 CBKinase1_015993 CS(=O)(=O)N(CC(=O)Nc1ccc(Br)cc1)c2ccc3OCCOc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D10 compound treatment 815877.0 -83100.0 -0.45 900579.0 16100.0 0.09 -0.2565 -0.5544 1552108 CBKinase1_015994 Cc1cc(C)c(C#N)c(SCC(O)CS(=O)(=O)c2ccc(cc2)C(C)(C)C)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D11 mock treatment 909179.0 10200.0 0.06 854505.0 -30000.0 -0.17 -0.0799 -0.4495 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D12 mock treatment 856005.0 -43000.0 -0.23 1013237.0 129000.0 0.73 0.3474 0.4555 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D13 compound treatment 1011792.0 113000.0 0.62 861751.0 -22700.0 -0.13 0.3451 0.5485 3626417 CBKinase1_015995 Cc1cccc(NC(=O)CN(c2ccc3OCCOc3c2)S(=O)(=O)C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D14 compound treatment 874185.0 -24800.0 -0.14 983922.0 99500.0 0.56 0.3008 0.5215 1193353 CBKinase1_015996 COc1ccc(cc1)c2cc(=O)c3cc(OCC(=O)Nc4ccc(C)cc4C)ccc3o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D15 mock treatment 834448.0 -64500.0 -0.35 806436.0 -78000.0 -0.44 -0.56 -0.9939 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D16 mock treatment 829491.0 -69500.0 -0.38 899989.0 15500.0 0.09 -0.2063 -0.53 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D17 compound treatment 814744.0 -84200.0 -0.46 882721.0 -1740.0 -0.01 -0.332 -0.722 3626418 CBKinase1_015997 CCc1cccc(C)c1NC(=O)CSc2nc3sc4CC(C)CCc4c3c(=O)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D18 compound treatment 845713.0 -53200.0 -0.29 951943.0 67500.0 0.38 0.0634 0.1324 1529209 CBKinase1_015998 Cc1cc(Cl)ccc1NC(=O)c2ccc(OCC(=O)Nc3ccccc3)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D19 compound treatment 825055.0 -73900.0 -0.4 850226.0 -34200.0 -0.19 -0.4217 -0.943 3626419 CBKinase1_015999 CS(=O)(=O)N(CC(=O)Nc1cc(ccc1Cl)C(F)(F)F)c2ccccc2Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D20 compound treatment 895691.0 -3270.0 -0.02 968186.0 83700.0 0.47 0.3211 0.6799 3626420 CBKinase1_016000 OC(=O)c1cc(NC(=O)C2CCCO2)cc(c1)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D21 compound treatment 622073.0 -277000.0 -1.51 801379.0 -83100.0 -0.47 -1.4 -0.8847 3626421 CBKinase1_016001 O=C(NCc1ccco1)C2(CCOCC2)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D22 compound treatment 643659.0 -255000.0 -1.39 783080.0 -101000.0 -0.57 -1.3896 -0.9225 1420689 CBKinase1_016002 COc1cc(cc(OC)c1OC)C(=O)Nc2ccc(Oc3ncnc4sc(C)c(C)c34)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D23 compound treatment 811671.0 -87300.0 -0.48 813314.0 -71100.0 -0.4 -0.6205 -0.9963 3626422 CBKinase1_016003 Cc1cc(C(=O)CSc2nnc3ccccn23)c(C)n1Cc4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 D24 compound treatment 786866.0 -112000.0 -0.61 851208.0 -33300.0 -0.19 -0.5653 -0.8832 3626423 CBKinase1_016004 Brc1ccc(cc1)S(=O)(=O)NCC(=O)Nc2cccc3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E01 mock treatment 751859.0 -147000.0 -0.8 651444.0 -233000.0 -1.31 -1.4966 -0.9721 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E02 mock treatment 795122.0 -104000.0 -0.57 488728.0 -396000.0 -2.23 -1.9781 -0.8595 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E03 compound treatment 783433.0 -116000.0 -0.63 673393.0 -211000.0 -1.19 -1.2872 -0.956 3626424 CBKinase1_016005 CC(N(c1ccccc1)S(=O)(=O)C)C(=O)Nc2ccccc2c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E04 compound treatment 805858.0 -93100.0 -0.51 700994.0 -183000.0 -1.03 -1.0906 -0.9465 3626425 CBKinase1_016006 CC(C)(C)c1cc(CN2CCOCC2)c(o1)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E05 compound treatment 857940.0 -41000.0 -0.22 746713.0 -138000.0 -0.78 -0.7073 -0.8754 3626426 CBKinase1_016007 CC(C)c1ccc(OCC(=O)Nc2ccc(O)cc2C(=O)O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E06 compound treatment 755569.0 -143000.0 -0.78 677396.0 -207000.0 -1.17 -1.3788 -0.9811 3626427 CBKinase1_016008 Cc1cccc(NC(=O)CSc2nnc(c3ccc(Cl)cc3)n2c4cccc(C)c4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E07 compound treatment 896987.0 -1970.0 -0.01 777712.0 -107000.0 -0.6 -0.4331 -0.7197 3118844 CBKinase1_016009 COc1ccc(C)cc1Cn2c(nc3ccccc23)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E08 compound treatment 796996.0 -102000.0 -0.56 765894.0 -119000.0 -0.67 -0.8662 -0.9959 3626428 CBKinase1_016010 NC(=O)C1CCN(CC1)C(=O)CSc2nc(O)cc(n2)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E09 mock treatment 791405.0 -108000.0 -0.59 735909.0 -149000.0 -0.84 -1.0073 -0.9849 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E10 mock treatment 800071.0 -98900.0 -0.54 764857.0 -120000.0 -0.67 -0.8584 -0.9939 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E11 compound treatment 845863.0 -53100.0 -0.29 755591.0 -129000.0 -0.73 -0.7186 -0.9188 3626429 CBKinase1_016011 Ic1ccc(OCC(=O)Nc2cccc(c2)c3nnc(o3)c4ccco4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E12 compound treatment 981654.0 82700.0 0.45 922874.0 38400.0 0.22 0.4723 0.9434 3626430 CBKinase1_016012 Fc1ccc(cc1)n2c(SCC(=O)c3ccc(Cl)cc3)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E13 compound treatment 842211.0 -56700.0 -0.31 742016.0 -142000.0 -0.8 -0.7868 -0.9143 1747657 CBKinase1_016013 Cc1ccc(cc1)c2nnn(CC(=O)Nc3ccc4OCCOc4c3)n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E14 compound treatment 877522.0 -21400.0 -0.12 806088.0 -78400.0 -0.44 -0.3951 -0.8646 3626431 CBKinase1_016014 CN(c1cccc(NC(=O)c2ccc(cc2)N(C)S(=O)(=O)c3ccccc3)c1)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E15 compound treatment 712104.0 -187000.0 -1.02 784760.0 -99700.0 -0.56 -1.1187 -0.9605 3626432 CBKinase1_016015 O=c1n(c(CSc2nc(Cc3ccccc3)nc4ccccc24)nc5ccccc15)c6ccccc6 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E16 compound treatment 818609.0 -80400.0 -0.44 792452.0 -92000.0 -0.52 -0.6769 -0.9965 3626433 CBKinase1_016016 COc1cccc(CO)c1OCC(=O)Nc2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E17 mock treatment 753935.0 -145000.0 -0.79 802312.0 -82100.0 -0.46 -0.8873 -0.9673 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E18 mock treatment 828010.0 -71000.0 -0.39 751690.0 -133000.0 -0.75 -0.8031 -0.953 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E19 compound treatment 750291.0 -149000.0 -0.81 719109.0 -165000.0 -0.93 -1.2329 -0.9976 3626434 CBKinase1_016017 COC(=O)COc1ccc(cc1)S(=O)(=O)NC2CCCCCC2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E20 compound treatment 664464.0 -234000.0 -1.28 672612.0 -212000.0 -1.19 -1.7496 -0.9994 3626435 CBKinase1_016018 CCn1c(SCC(=O)Nc2cccc(SC)c2)nnc1c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E21 compound treatment 701764.0 -197000.0 -1.08 696268.0 -188000.0 -1.06 -1.5113 -1.0 3626436 CBKinase1_016019 COc1ccccc1OCC(=O)Nc2cccc(c2)c3nc4ccccc4o3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E22 compound treatment 595565.0 -303000.0 -1.66 661576.0 -223000.0 -1.26 -2.0596 -0.9907 3626437 CBKinase1_016020 CCn1c(SCC(=O)Nc2cc(Cl)c(Cl)cc2Cl)nnc1c3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E23 compound treatment 705626.0 -193000.0 -1.06 671002.0 -213000.0 -1.2 -1.5971 -0.9979 3626438 CBKinase1_016021 COc1cc(CO)cc(I)c1OCc2cccc(c2)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 E24 compound treatment 721667.0 -177000.0 -0.97 725811.0 -159000.0 -0.89 -1.3167 -0.9992 3626439 CBKinase1_016022 O=C1N(OS(=O)(=O)c2cccc3cccnc23)C(=O)c4ccccc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F01 mock treatment 495078.0 -404000.0 -2.2 801209.0 -83200.0 -0.47 -1.891 -0.8388 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F02 mock treatment 798675.0 -100000.0 -0.55 774039.0 -110000.0 -0.62 -0.8272 -0.998 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F03 compound treatment 634579.0 -264000.0 -1.44 792330.0 -92100.0 -0.52 -1.3878 -0.9047 3626440 CBKinase1_016023 COc1ccc(Cl)cc1NC(=O)CN(C)S(=O)(=O)c2c(C)cc(C)cc2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F04 compound treatment 671035.0 -228000.0 -1.24 716252.0 -168000.0 -0.95 -1.5503 -0.991 3626441 CBKinase1_016024 COc1ccc(OC)c(c1)N(CC(=O)Nc2ccc(I)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F05 compound treatment 682910.0 -216000.0 -1.18 725598.0 -159000.0 -0.9 -1.4672 -0.9908 3626442 CBKinase1_016025 CN(C)S(=O)(=O)c1cccc(NC(=O)c2c(C)onc2c3ccccc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F06 compound treatment 794023.0 -105000.0 -0.57 789687.0 -94800.0 -0.53 -0.7828 -0.9994 3626443 CBKinase1_016026 CCn1c(SCC(=O)Nc2ccccc2C)nnc1c3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F07 compound treatment 793574.0 -105000.0 -0.58 855176.0 -29300.0 -0.17 -0.5235 -0.8747 3626444 CBKinase1_016027 COC(=O)c1ccccc1NC(=O)CN(c2cccc(F)c2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F08 compound treatment 712615.0 -186000.0 -1.02 750526.0 -134000.0 -0.75 -1.2532 -0.9892 3626445 CBKinase1_016028 CC(C)NS(=O)(=O)c1ccc(OCC(=O)O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F09 mock treatment 900201.0 1240.0 0.01 907184.0 22700.0 0.13 0.0954 0.7435 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F10 mock treatment 780647.0 -118000.0 -0.65 824359.0 -60100.0 -0.34 -0.6963 -0.9546 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F11 compound treatment 848001.0 -51000.0 -0.28 855245.0 -29200.0 -0.16 -0.3132 -0.9687 3626446 CBKinase1_016029 Clc1cccc(NC(=O)CSc2nnc(o2)c3ccco3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F12 compound treatment 787264.0 -112000.0 -0.61 900001.0 15500.0 0.09 -0.3693 -0.5994 3626447 CBKinase1_016030 O=C(Nc1ccccc1C(=O)NCc2ccco2)C3COc4ccccc4O3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F13 compound treatment 882023.0 -16900.0 -0.09 735963.0 -148000.0 -0.84 -0.6572 -0.7805 3626448 CBKinase1_016031 COC(=O)c1ccccc1NC(=O)COc2cccc(Cl)c2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F14 compound treatment 752705.0 -146000.0 -0.8 844106.0 -40400.0 -0.23 -0.7254 -0.8738 3626449 CBKinase1_016032 COc1ccccc1OCC(=O)Nc2ccc(C)cc2[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F15 compound treatment 855256.0 -43700.0 -0.24 887368.0 2910.0 0.02 -0.1571 -0.657 1648710 CBKinase1_016033 Cc1ccc(C)c(NC(=O)Cn2cnc3ccccc3c2=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F16 compound treatment 815756.0 -83200.0 -0.45 783515.0 -101000.0 -0.57 -0.7235 -0.9938 3626450 CBKinase1_016034 Cc1cccc(OCC(=O)Nc2ccc(cc2C)C(=O)Nc3ccccc3C(=O)O)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F17 mock treatment 684538.0 -214000.0 -1.17 812770.0 -71700.0 -0.4 -1.1135 -0.8991 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F18 mock treatment 827773.0 -71200.0 -0.39 882742.0 -1720.0 -0.01 -0.2817 -0.7245 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F19 compound treatment 618505.0 -280000.0 -1.53 700905.0 -184000.0 -1.03 -1.8142 -0.9818 3626451 CBKinase1_016035 Cc1cc(C)nc(n1)N(C#N)C(C(=O)c2ccccc2)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F20 compound treatment 769444.0 -130000.0 -0.71 694421.0 -190000.0 -1.07 -1.2574 -0.9797 3626452 CBKinase1_016036 CC(=O)c1cccc(c1)n2c(CCC(=O)O)ccc2c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F21 compound treatment 643463.0 -255000.0 -1.39 692756.0 -192000.0 -1.08 -1.7504 -0.992 1179133 CBKinase1_016037 Cc1cc(C)c(C#N)c(SCC(O)CS(=O)c2ccc(cc2)C(C)(C)C)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F22 compound treatment 683835.0 -215000.0 -1.17 571286.0 -313000.0 -1.77 -2.0786 -0.9804 1859504 CBKinase1_016038 COC(=O)c1ccccc1NC(=O)CCSc2ccc(C)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F23 compound treatment 582870.0 -316000.0 -1.73 705674.0 -179000.0 -1.01 -1.9328 -0.9672 3626453 CBKinase1_016039 COc1ccc(cc1NC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 F24 compound treatment 767298.0 -132000.0 -0.72 601821.0 -283000.0 -1.59 -1.6347 -0.9354 3088333 CBKinase1_016040 CN(CC(=O)Nc1ccc(NC(=O)C)cc1)S(=O)(=O)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G01 compound treatment 797876.0 -101000.0 -0.55 768071.0 -116000.0 -0.66 -0.8541 -0.9963 3626454 CBKinase1_016041 Clc1ccccc1NC(=O)CSc2ncnc3sc(cc23)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G02 compound treatment 850988.0 -48000.0 -0.26 812543.0 -71900.0 -0.41 -0.4718 -0.9777 1218742 CBKinase1_016042 O=C(Nc1ccccc1)Nc2ccccc2C(=O)NCc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G03 mock treatment 907379.0 8420.0 0.05 803607.0 -80900.0 -0.46 -0.2897 -0.6326 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G04 mock treatment 862699.0 -36300.0 -0.2 844023.0 -40400.0 -0.23 -0.3011 -0.9975 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G05 compound treatment 884188.0 -14800.0 -0.08 847943.0 -36500.0 -0.21 -0.2026 -0.9163 1224155 CBKinase1_016043 CC(Oc1ccc2c(=O)c(coc2c1)c3ccc(Cl)cc3)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G06 compound treatment 876909.0 -22100.0 -0.12 789353.0 -95100.0 -0.54 -0.4642 -0.8449 3626455 CBKinase1_016044 Cc1cc(NC(=O)C2CC=CCC2C(=O)O)ccc1NC(=O)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G07 compound treatment 935315.0 36400.0 0.2 809317.0 -75100.0 -0.42 -0.1591 -0.3402 3626456 CBKinase1_016045 Cc1c(sc2ncn(CC(=O)Nc3ccc(C)cc3)c(=O)c12)C(=O)Nc4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G08 compound treatment 952047.0 53100.0 0.29 847304.0 -37200.0 -0.21 0.0569 0.159 3626457 CBKinase1_016046 OCc1c(OCc2ccccc2C#N)ccc3ccccc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G09 compound treatment 890958.0 -8000.0 -0.04 837795.0 -46700.0 -0.26 -0.2169 -0.8134 1318561 CBKinase1_016047 Cc1ccc(NCC(O)CSc2nc3CCCCc3cc2C#N)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G10 compound treatment 865985.0 -33000.0 -0.18 838283.0 -46200.0 -0.26 -0.3113 -0.9838 3626458 CBKinase1_016048 CN(CC(=O)Nc1cc(Cl)ccc1C)S(=O)(=O)c2c(C)cc(C)cc2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G11 compound treatment 908863.0 9900.0 0.05 868365.0 -16100.0 -0.09 -0.0259 -0.2454 3626459 CBKinase1_016049 COC(=O)c1ccccc1NC(=O)CNS(=O)(=O)c2c(C)cc(C)cc2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G12 compound treatment 900231.0 1270.0 0.01 896783.0 12300.0 0.07 0.054 0.7739 3626460 CBKinase1_016050 OC(=O)c1cc(NC(=O)COc2ccc(Cl)cc2Cl)cc(c1)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G13 compound treatment 916147.0 17200.0 0.09 818892.0 -65600.0 -0.37 -0.195 -0.5113 3626461 CBKinase1_016051 CCS(=O)(=O)CCSc1nc(C)c(C(=O)Nc2ccccc2)c(c1C#N)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G14 compound treatment 921405.0 22400.0 0.12 887445.0 2990.0 0.02 0.0986 0.7968 3626462 CBKinase1_016052 CN(C)c1ccc(cc1)n2c(CCC(=O)O)ccc2c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G15 compound treatment 544029.0 -355000.0 -1.94 510861.0 -374000.0 -2.11 -2.8592 -0.9991 3626463 CBKinase1_016053 COc1ccccc1OCC(=O)Nc2cc(Cl)ccc2O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G16 compound treatment 973239.0 74300.0 0.41 830835.0 -53600.0 -0.3 0.073 0.1444 3626464 CBKinase1_016054 CCOc1ccc(cc1)n2c(SCC(=O)OC)nnc2c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G17 compound treatment 905401.0 6440.0 0.04 860316.0 -24100.0 -0.14 -0.0714 -0.5077 3626465 CBKinase1_016055 CCOc1ccc(cc1)n2c(SCc3cccc(c3)[N+](=O)[O-])nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G18 compound treatment 869507.0 -29500.0 -0.16 807223.0 -77200.0 -0.44 -0.4215 -0.9083 3626466 CBKinase1_016056 CCc1ccc(cc1)n2c(SCC(=O)Nc3cc(Cl)ccc3C)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G19 mock treatment 837602.0 -61400.0 -0.33 782623.0 -102000.0 -0.57 -0.6427 -0.9671 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G20 mock treatment 802196.0 -96800.0 -0.53 769360.0 -115000.0 -0.65 -0.8323 -0.9948 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G21 compound treatment 805336.0 -93600.0 -0.51 733824.0 -151000.0 -0.85 -0.9618 -0.9705 3626467 CBKinase1_016057 COc1ccccc1OCC(=O)Nc2cc(ccc2C)C(=O)Nc3ccccc3C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G22 compound treatment 733338.0 -166000.0 -0.9 730299.0 -154000.0 -0.87 -1.2538 -0.9998 3626468 CBKinase1_016058 CCn1c(SCC(=O)Nc2ccccc2C)nc3ccc(I)cc3c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G23 compound treatment 819191.0 -79800.0 -0.44 759003.0 -125000.0 -0.71 -0.808 -0.9729 3626469 CBKinase1_016059 CSc1cccc(NC(=O)CNS(=O)(=O)c2c(C)cc(C)cc2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 G24 compound treatment 878814.0 -20100.0 -0.11 734112.0 -150000.0 -0.85 -0.677 -0.7922 3626470 CBKinase1_016060 CC1(C)CC(CCO1)NC(=O)CC(c2ccco2)c3ccc(F)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H01 compound treatment 769023.0 -130000.0 -0.71 813180.0 -71300.0 -0.4 -0.7857 -0.9637 3626471 CBKinase1_016061 Brc1ccc(NC(=O)CSc2nnc([nH]2)c3ccncc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H02 compound treatment 838916.0 -60000.0 -0.33 854334.0 -30100.0 -0.17 -0.3519 -0.9531 3626472 CBKinase1_016062 Ic1ccc(NC(=O)CSc2nc3ccccc3[nH]2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H03 mock treatment 879797.0 -19200.0 -0.1 860239.0 -24200.0 -0.14 -0.1705 -0.9914 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H04 mock treatment 870143.0 -28800.0 -0.16 901277.0 16800.0 0.09 -0.0442 -0.2407 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H05 compound treatment 850208.0 -48800.0 -0.27 904439.0 20000.0 0.11 -0.1086 -0.3757 3626473 CBKinase1_016063 COc1ccc(OC)c(c1)N(CC(=O)Nc2c(C)cc(C)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H06 compound treatment 923310.0 24300.0 0.13 1370778.0 486000.0 2.74 2.0322 0.7405 3626474 CBKinase1_016064 CS(=O)(=O)N(CC(=O)Nc1cc(ccc1Cl)C(F)(F)F)c2ccc(Br)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H07 compound treatment 914849.0 15900.0 0.09 893732.0 9270.0 0.05 0.0983 0.9706 3626475 CBKinase1_016065 CS(=O)(=O)N(CC(=O)Nc1ccccc1C(F)(F)F)c2ccc3OCCOc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H08 compound treatment 961997.0 63000.0 0.34 894356.0 9900.0 0.06 0.2828 0.8111 3626476 CBKinase1_016066 Cc1cc(NC(=O)CSc2nnc(c3ccccc3)n2c4ccc(F)cc4)ccc1Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H09 compound treatment 876597.0 -22400.0 -0.12 866541.0 -17900.0 -0.1 -0.1577 -0.9956 3626477 CBKinase1_016067 CCC(=O)Nc1ccc(Cl)c(NC(=O)COc2ccccc2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H10 compound treatment 885351.0 -13600.0 -0.07 886523.0 2060.0 0.01 -0.0443 -0.5892 3626478 CBKinase1_016068 CS(=O)(=O)N(CC(=O)Nc1cccc(c1)[N+](=O)[O-])c2ccc3CCc4cccc2c43 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H11 compound treatment 908663.0 9700.0 0.05 871407.0 -13100.0 -0.07 -0.0146 -0.1606 3626479 CBKinase1_016069 Cc1c(Cl)cccc1NC(=O)CN(c2ccc3OCCOc3c2)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H12 compound treatment 901951.0 2990.0 0.02 963627.0 79200.0 0.45 0.3271 0.7325 3626480 CBKinase1_016070 CS(=O)(=O)N(CC(=O)Nc1cc(ccc1Cl)C(F)(F)F)c2ccc(I)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H13 compound treatment 924203.0 25200.0 0.14 872283.0 -12200.0 -0.07 0.0489 0.3178 3626481 CBKinase1_016071 Clc1ccc(NC(=O)CSc2nc(cs2)c3ccccc3)c(Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H14 compound treatment 1001892.0 103000.0 0.56 967091.0 82600.0 0.47 0.7267 0.9956 3626482 CBKinase1_016072 CC(=O)c1ccc(cc1)n2c(CCC(=O)O)ccc2c3cccs3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H15 compound treatment 927380.0 28400.0 0.16 932087.0 47600.0 0.27 0.2995 0.966 3626483 CBKinase1_016073 COc1cccc(NC(=O)CSc2nc3ccccc3c(=O)n2c4cccc(c4)C(F)(F)F)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H16 compound treatment 915533.0 16600.0 0.09 943310.0 58900.0 0.33 0.2985 0.8683 3626484 CBKinase1_016074 COc1cccc(NC(=O)CSc2nnc(C)n2c3ccc(F)cc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H17 compound treatment 986419.0 87500.0 0.48 884514.0 55.7 0.0 0.3379 0.7076 3626485 CBKinase1_016075 Cn1c(SCC(=O)Nc2ccccc2Cl)nnc1c3cccc(c3)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H18 compound treatment 952668.0 53700.0 0.29 887251.0 2790.0 0.02 0.2185 0.744 3626486 CBKinase1_016076 Cc1cc(C)c(NC(=O)CSc2nnc(c3ccncc3)n2c4ccc(F)cc4)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H19 mock treatment 933541.0 34600.0 0.19 864819.0 -19600.0 -0.11 0.0552 0.2523 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H20 mock treatment 916004.0 17000.0 0.09 881784.0 -2670.0 -0.02 0.0551 0.5849 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H21 compound treatment 868038.0 -30900.0 -0.17 839610.0 -44800.0 -0.25 -0.2981 -0.9807 3626487 CBKinase1_016077 CC(N(c1ccc(Oc2ccccc2)cc1)S(=O)(=O)C)C(=O)Nc3c(C)cc(C)cc3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H22 compound treatment 857666.0 -41300.0 -0.23 854365.0 -30100.0 -0.17 -0.2794 -0.9902 3626488 CBKinase1_016078 Cc1ccccc1OCC(=O)Nc2ccc(O)cc2C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H23 compound treatment 849719.0 -49200.0 -0.27 834516.0 -49900.0 -0.28 -0.3891 -0.9997 3025041 CBKinase1_016079 OC(=O)CCSC1CC(=O)N(C1=O)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 H24 compound treatment 760087.0 -139000.0 -0.76 774340.0 -110000.0 -0.62 -0.975 -0.9951 1629454 CBKinase1_016080 Cc1ccc(cc1)S(=O)(=O)N2CCN(CC2)C(=O)CSc3nnc4sc5ccccc5n34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I01 compound treatment 715622.0 -183000.0 -1.0 1297656.0 413000.0 2.33 0.939 0.3704 3626489 CBKinase1_016081 COc1cccc(c1)C(=O)NCCNC2=NS(=O)(=O)c3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I02 compound treatment 856232.0 -42700.0 -0.23 939173.0 54700.0 0.31 0.0531 0.1374 3626490 CBKinase1_016082 OC(=O)c1ccccc1NC(=O)COc2cccc3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I03 compound treatment 942080.0 43100.0 0.24 922766.0 38300.0 0.22 0.3191 0.9991 3626491 CBKinase1_016083 COc1ccc(cc1Cl)N(CC(=O)Nc2ccc(I)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I04 compound treatment 952731.0 53800.0 0.29 927490.0 43000.0 0.24 0.3791 0.9955 3626492 CBKinase1_016084 O=C(CSc1nnc([nH]1)c2ccccc2)Nc3sc4CCCCc4c3C(=O)Nc5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I05 mock treatment 983879.0 84900.0 0.46 929100.0 44600.0 0.25 0.5057 0.9588 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I06 mock treatment 1001909.0 103000.0 0.56 1018719.0 134000.0 0.76 0.9325 0.9893 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I07 compound treatment 1030932.0 132000.0 0.72 1018711.0 134000.0 0.76 1.0445 0.9997 3626493 CBKinase1_016085 Cc1cc(C)c(NC(=O)CN(c2ccc(Oc3ccccc3)cc2)S(=O)(=O)C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I08 compound treatment 1044387.0 145000.0 0.79 940897.0 56400.0 0.32 0.7864 0.9194 3626494 CBKinase1_016086 Cc1nc2cc(NC(=O)NCc3ccco3)ccc2n1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I09 compound treatment 1021545.0 123000.0 0.67 967382.0 82900.0 0.47 0.8037 0.9846 3626495 CBKinase1_016087 COc1ccc(cc1)n2c(C)nnc2SCC(=O)Nc3cccc(c3)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I10 compound treatment 933448.0 34500.0 0.19 1026748.0 142000.0 0.8 0.7002 0.85 3626496 CBKinase1_016088 CS(=O)(=O)N(CC(=O)Nc1ccccc1c2ccccc2)c3cccc(c3)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I11 compound treatment 1010481.0 112000.0 0.61 1084124.0 200000.0 1.13 1.2263 0.9584 3626497 CBKinase1_016089 Cc1ccc(NC(=O)COc2ccc(CO)cc2Br)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I12 compound treatment 996963.0 98000.0 0.54 973250.0 88800.0 0.5 0.7322 0.9994 3626498 CBKinase1_016090 CCc1cccc(C)c1NC(=O)CSc2nnc(C)n2c3ccc(F)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I13 compound treatment 968526.0 69600.0 0.38 881555.0 -2900.0 -0.02 0.257 0.676 3626499 CBKinase1_016091 [O-][N+](=O)c1ccc2C(=O)N(CCC(=O)Nc3cccc(I)c3)C(=O)c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I14 compound treatment 1025813.0 127000.0 0.69 1058477.0 174000.0 0.98 1.1833 0.9855 3626500 CBKinase1_016092 COC(=O)c1c(NC(=O)CN(c2cccc(Br)c2)S(=O)(=O)C)sc3CCCCc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I15 compound treatment 1068714.0 170000.0 0.93 998872.0 114000.0 0.64 1.1113 0.9843 3626501 CBKinase1_016093 Cc1cc(NC(=O)C2CCCCC2C(=O)O)ccc1NC(=O)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I16 compound treatment 1001850.0 103000.0 0.56 888594.0 4140.0 0.02 0.4137 0.7358 3626502 CBKinase1_016094 OC(=O)c1ccc(Cl)cc1NC(=O)COc2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I17 compound treatment 968832.0 69900.0 0.38 970087.0 85600.0 0.48 0.611 0.9932 3626503 CBKinase1_016095 OCc1ccccc1OCC(=O)Nc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I18 compound treatment 962569.0 63600.0 0.35 1001669.0 117000.0 0.66 0.7127 0.9549 3626504 CBKinase1_016096 COc1ccccc1c2c(oc3cc(OCC(=O)Nc4cc(C)ccc4C)ccc3c2=O)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I19 compound treatment 1024216.0 125000.0 0.68 897164.0 12700.0 0.07 0.5342 0.7769 3626505 CBKinase1_016097 COc1cccc(c1)n2nnnc2SCC(=O)Nc3ccccc3OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I20 compound treatment 864466.0 -34500.0 -0.19 967110.0 82700.0 0.47 0.1962 0.3906 3626506 CBKinase1_016098 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cnn3c(cc(nc23)c4ccc(C)cc4)C(F)F)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I21 mock treatment 939630.0 40700.0 0.22 847376.0 -37100.0 -0.21 0.0092 0.0302 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I22 mock treatment 904471.0 5510.0 0.03 874234.0 -10200.0 -0.06 -0.0195 -0.2996 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I23 compound treatment 911811.0 12900.0 0.07 919131.0 34700.0 0.2 0.1878 0.9044 1348377 CBKinase1_016099 Cc1cc(C)c(C#N)c(SCC(O)COc2ccc(Cl)cc2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 I24 compound treatment 843699.0 -55300.0 -0.3 962907.0 78400.0 0.44 0.0993 0.1856 3626507 CBKinase1_016100 Clc1ccc(NC(=O)CN2C(=O)CNC2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J01 compound treatment 859860.0 -39100.0 -0.21 917481.0 33000.0 0.19 -0.0193 -0.0683 3626508 CBKinase1_016101 CCOC(=O)c1c(C)n(C)c2ccc(OC(=O)CN3C(=O)c4ccccc4C3=O)cc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J02 compound treatment 892578.0 -6380.0 -0.03 935272.0 50800.0 0.29 0.1779 0.6165 3626509 CBKinase1_016102 CCc1cccc(C)c1NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J03 compound treatment 909611.0 10700.0 0.06 907237.0 22800.0 0.13 0.1319 0.9358 3626510 CBKinase1_016103 Cc1ccc(cc1)c2csc3ncn(CC(=O)Nc4cc(Cl)ccc4Cl)c(=O)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J04 compound treatment 930789.0 31800.0 0.17 971659.0 87200.0 0.49 0.4704 0.9024 3626511 CBKinase1_016104 Cc1nnc(SCC(=O)Nc2cccc(C)c2C)n1c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J05 mock treatment 935879.0 36900.0 0.2 952088.0 67600.0 0.38 0.4121 0.9556 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J06 mock treatment 904455.0 5490.0 0.03 906289.0 21800.0 0.12 0.1082 0.8545 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J07 compound treatment 959381.0 60400.0 0.33 970644.0 86200.0 0.49 0.5767 0.9822 3626512 CBKinase1_016105 CS(=O)(=O)N(CC(=O)Nc1cc(Cl)ccc1Cl)c2ccc3OCCOc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J08 compound treatment 1040923.0 142000.0 0.78 1006223.0 122000.0 0.69 1.0333 0.9982 3626513 CBKinase1_016106 CC(C)c1ccc(OCC(=O)Nc2ccc(Br)cc2C(=O)O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J09 compound treatment 995441.0 96500.0 0.53 1008541.0 124000.0 0.7 0.867 0.9902 3626514 CBKinase1_016107 COCCCNC1=NS(=O)(=O)c2ccccc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J10 compound treatment 950968.0 52000.0 0.28 980321.0 95900.0 0.54 0.5828 0.9549 3626515 CBKinase1_016108 Cc1nnc(SCC(=O)Nc2ccc(Br)cc2)n1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J11 compound treatment 975894.0 76900.0 0.42 974473.0 90000.0 0.51 0.6558 0.9956 3626516 CBKinase1_016109 CC(=O)c1ccc(NC(=O)CSc2nnc(n2C)C3(CC4CC5CC(C4)C3)C5)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J12 compound treatment 986054.0 87100.0 0.48 1032446.0 148000.0 0.83 0.926 0.9645 3626517 CBKinase1_016110 Cc1ccc(cc1)S(=O)(=O)NCC(=O)Nc2cccc(Cl)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J13 compound treatment 990056.0 91100.0 0.5 1015363.0 131000.0 0.74 0.8734 0.9816 3626518 CBKinase1_016111 COc1ccc(cc1)C(Nc2cc(C)ccn2)c3ccc4ccc(C)nc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J14 compound treatment 996914.0 98000.0 0.53 1079129.0 195000.0 1.1 1.154 0.9454 3626519 CBKinase1_016112 CCOC(=O)c1sc(NC(=O)CSc2ncccn2)c(C#N)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J15 compound treatment 995114.0 96200.0 0.52 950754.0 66300.0 0.37 0.6354 0.9861 3626520 CBKinase1_016113 COc1cc(NC(=O)COc2ccc(Br)cc2)ccc1NC(=O)c3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J16 compound treatment 1057873.0 159000.0 0.87 1043857.0 159000.0 0.9 1.2488 0.9998 1579979 CBKinase1_016114 OC(COc1ccc(Cl)cc1Cl)CN2C(=O)c3ccccc3S2(=O)=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J17 compound treatment 982631.0 83700.0 0.46 990308.0 106000.0 0.6 0.7449 0.9913 1594715 CBKinase1_016115 COC(=O)c1ccccc1NC(=O)CN2C(=O)c3ccccc3S2(=O)=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J18 compound treatment 1018775.0 120000.0 0.65 1024712.0 140000.0 0.79 1.0215 0.9956 3626521 CBKinase1_016116 Cc1nnc(SCC(=O)Nc2ccc(Br)c(C)c2)n1c3ccc(C)c(C)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J19 compound treatment 1014816.0 116000.0 0.63 990219.0 106000.0 0.6 0.8688 0.9996 1743765 CBKinase1_016117 CCn1c(SCC(=O)N2c3ccccc3Sc4ccccc24)nnc1c5ccncc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J20 compound treatment 997942.0 99000.0 0.54 901324.0 16900.0 0.1 0.4493 0.8189 1985766 CBKinase1_016118 COc1ccccc1c2nc(SCC(=O)c3ccc(O)c(O)c3)n[nH]2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J21 mock treatment 942035.0 43100.0 0.24 910116.0 25700.0 0.14 0.2685 0.9727 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J22 mock treatment 893903.0 -5060.0 -0.03 797315.0 -87100.0 -0.49 -0.3668 -0.7457 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J23 compound treatment 839790.0 -59200.0 -0.32 843823.0 -40600.0 -0.23 -0.3904 -0.9858 3626522 CBKinase1_016119 Clc1cccc(NC(=O)CSc2nc3ccccc3s2)c1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 J24 compound treatment 904416.0 5460.0 0.03 666096.0 -218000.0 -1.23 -0.8492 -0.6898 3626523 CBKinase1_016120 Cc1sc2nc(SCC(=O)NCC3CCCO3)n(c4ccccc4)c(=O)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K01 compound treatment 853598.0 -45400.0 -0.25 923672.0 39200.0 0.22 -0.0188 -0.0567 1421918 CBKinase1_016121 Fc1ccc(NC(=O)c2ccc(OCC(=O)Nc3cc(Cl)cc(Cl)c3)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K02 compound treatment 827732.0 -71200.0 -0.39 770822.0 -114000.0 -0.64 -0.7279 -0.9714 3626524 CBKinase1_016122 CCOC(=O)c1c(NC(=O)CSc2ncccn2)sc3CCCCc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K03 compound treatment 802808.0 -96200.0 -0.52 859447.0 -25000.0 -0.14 -0.4709 -0.8663 3626525 CBKinase1_016123 CCn1c(SCC(=O)Nc2cc(Cl)cc(Cl)c2)nnc1c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K04 compound treatment 881571.0 -17400.0 -0.09 874342.0 -10100.0 -0.06 -0.1074 -0.9703 3626526 CBKinase1_016124 COc1ccc(NC(=O)c2ccccc2NC(=O)COc3ccc(cc3)[N+](=O)[O-])cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K05 compound treatment 908680.0 9720.0 0.05 818133.0 -66300.0 -0.37 -0.2268 -0.6007 3626527 CBKinase1_016125 Cc1cc(C)c(c(C)c1)S(=O)(=O)NCC(=O)Nc2cccc(Cl)c2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K06 compound treatment 790635.0 -108000.0 -0.59 742677.0 -142000.0 -0.8 -0.9833 -0.989 3626528 CBKinase1_016126 Cc1cc(C)nc(n1)N(CC(=O)c2ccccc2)C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K07 mock treatment 945845.0 46900.0 0.26 868758.0 -15700.0 -0.09 0.1184 0.4373 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K08 mock treatment 949725.0 50800.0 0.28 905992.0 21500.0 0.12 0.2818 0.9314 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K09 compound treatment 962805.0 63800.0 0.35 877178.0 -7280.0 -0.04 0.2175 0.6196 3626529 CBKinase1_016127 CC(=O)c1ccc(cc1)n2c(CCC(=O)O)ccc2c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K10 compound treatment 1123792.0 225000.0 1.23 958083.0 73600.0 0.41 1.1614 0.8963 3626530 CBKinase1_016128 OCCOCCNc1nn2c(=O)c3c4CCCCc4sc3nc2c5ccccc15 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K11 compound treatment 926155.0 27200.0 0.15 850297.0 -34200.0 -0.19 -0.0312 -0.1282 3626531 CBKinase1_016129 COC(=O)c1c(NC(=O)CSc2ncnc3sc4CCCc4c23)scc1c5ccc(F)cc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K12 compound treatment 901712.0 2750.0 0.02 879987.0 -4470.0 -0.03 -0.0072 -0.2453 3626532 CBKinase1_016130 Cc1cc(C)c(NC(=O)CN(c2cc(Cl)cc(Cl)c2)S(=O)(=O)C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K13 compound treatment 946880.0 47900.0 0.26 942653.0 58200.0 0.33 0.4169 0.9937 3626533 CBKinase1_016131 NC(=O)C1CCN(CC1)C(=O)CSc2nnnn2c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K14 compound treatment 982977.0 84000.0 0.46 881770.0 -2690.0 -0.02 0.3136 0.6834 3626534 CBKinase1_016132 COc1cccc(NC(=O)CSc2nnc(c3ccc(Cl)cc3)n2c4cccc(C)c4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K15 mock treatment 987438.0 88500.0 0.48 868848.0 -15600.0 -0.09 0.2793 0.5689 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K16 mock treatment 910834.0 11900.0 0.06 864591.0 -19900.0 -0.11 -0.0333 -0.2577 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K17 compound treatment 1000280.0 101000.0 0.55 867774.0 -16700.0 -0.09 0.3246 0.5786 3626535 CBKinase1_016133 CCc1ccc(NC(=O)COc2ccc(NC(=O)C)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K18 compound treatment 949296.0 50300.0 0.27 887145.0 2690.0 0.02 0.205 0.7449 3626536 CBKinase1_016134 Cc1nc(SCC(=O)c2cc3ccccc3oc2=O)c(C(=O)N)c(C)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K19 compound treatment 889916.0 -9040.0 -0.05 799481.0 -85000.0 -0.48 -0.3736 -0.7759 3626537 CBKinase1_016135 Clc1ccc(NC(=O)CSc2nnc(c3ccccc3)n2c4ccc(Cl)cc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K20 compound treatment 845622.0 -53300.0 -0.29 828620.0 -55800.0 -0.31 -0.4285 -0.9992 3626538 CBKinase1_016136 Ic1ccc(NC(=O)c2cccnc2)c(c1)C(=O)NCCN3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K21 compound treatment 893897.0 -5060.0 -0.03 752222.0 -132000.0 -0.75 -0.5466 -0.7328 3626539 CBKinase1_016137 COc1ccccc1N(CC(=O)Nc2ccc(I)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K22 compound treatment 627786.0 -271000.0 -1.48 750723.0 -134000.0 -0.75 -1.5799 -0.951 3626540 CBKinase1_016138 CC(=O)OC(COc1cccc2ccccc12)Cn3cnc4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K23 mock treatment 692621.0 -206000.0 -1.13 793556.0 -90900.0 -0.51 -1.1589 -0.9364 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 K24 mock treatment 886007.0 -13000.0 -0.07 732993.0 -151000.0 -0.85 -0.6537 -0.7631 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L01 compound treatment 887887.0 -11100.0 -0.06 1051845.0 167000.0 0.94 0.6244 0.6604 3626541 CBKinase1_016139 Cc1ccccc1NC(=O)CSc2cc(C)c3ccccc3n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L02 compound treatment 865381.0 -33600.0 -0.18 849611.0 -34800.0 -0.2 -0.2685 -0.9994 3626542 CBKinase1_016140 Cc1cc2nnc(SCC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)n2c4ccccc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L03 compound treatment 900385.0 1420.0 0.01 821910.0 -62500.0 -0.35 -0.2438 -0.6913 3626543 CBKinase1_016141 Cc1ccc(C)c(NC(=O)COc2ccc(cc2)C(=O)Nc3ccccc3C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L04 compound treatment 804477.0 -94500.0 -0.52 938253.0 53800.0 0.3 -0.1503 -0.2513 1986212 CBKinase1_016142 OC(=O)c1cccc(NS(=O)(=O)c2cccc3cccnc23)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L05 compound treatment 974895.0 75900.0 0.41 896896.0 12400.0 0.07 0.3427 0.8151 3626544 CBKinase1_016143 Cc1ccc(cc1[N+](=O)[O-])C(=O)Nc2ccccc2C(=O)NCc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L06 compound treatment 999693.0 101000.0 0.55 920226.0 35800.0 0.2 0.5314 0.9073 1598220 CBKinase1_016144 CN1C(=O)c2cccc(NC(=O)C3COc4ccccc4O3)c2C1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L07 mock treatment 930954.0 32000.0 0.17 967092.0 82600.0 0.47 0.4529 0.9104 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L08 mock treatment 903164.0 4200.0 0.02 934922.0 50500.0 0.28 0.2174 0.7617 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L09 compound treatment 1022054.0 123000.0 0.67 922177.0 37700.0 0.21 0.6255 0.8875 3626545 CBKinase1_016145 Cc1cc(C)c(NC(=O)CSc2nnc(c3ccc(F)cc3)n2C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L10 compound treatment 980658.0 81700.0 0.45 1011980.0 128000.0 0.72 0.8236 0.9737 3626546 CBKinase1_016146 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)Nc2ccccc2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L11 compound treatment 990801.0 91800.0 0.5 933770.0 49300.0 0.28 0.5511 0.9613 3626547 CBKinase1_016147 COC(=O)c1ccc(NC(=O)CN(c2ccc3OCCOc3c2)S(=O)(=O)C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L12 compound treatment 931103.0 32100.0 0.18 997922.0 113000.0 0.64 0.5763 0.869 3626548 CBKinase1_016148 CN(CC(=O)N)S(=O)(=O)c1ccc(F)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L13 compound treatment 1063079.0 164000.0 0.9 908245.0 23800.0 0.13 0.7284 0.804 3626549 CBKinase1_016149 COc1ccc(OC)c(NC(=O)CSc2nnc(c3ccc(Cl)cc3Cl)n2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L14 compound treatment 970874.0 71900.0 0.39 994240.0 110000.0 0.62 0.7152 0.9759 1418488 CBKinase1_016150 COc1ccc(Cl)cc1NC(=O)CN2C(=O)c3ccccc3S2(=O)=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L15 mock treatment 1015382.0 116000.0 0.64 887148.0 2690.0 0.02 0.4602 0.7238 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L16 mock treatment 981379.0 82400.0 0.45 963407.0 78900.0 0.44 0.6328 1.0 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L17 compound treatment 932440.0 33500.0 0.18 890652.0 6190.0 0.03 0.1539 0.8272 3626550 CBKinase1_016151 Cc1ccc(cc1C)n2c(SCC(=O)c3ccccc3)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L18 compound treatment 988841.0 89900.0 0.49 888837.0 4380.0 0.02 0.3644 0.7417 3626551 CBKinase1_016152 Cn1c(=O)n(C)c2nc(SCC(=O)N)n(Cc3ccccc3F)c2c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L19 compound treatment 975310.0 76300.0 0.42 959900.0 75400.0 0.43 0.5954 1.0 3626552 CBKinase1_016153 Cc1cccc(NC(=O)CNS(=O)(=O)c2ccc(Br)cc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L20 compound treatment 982223.0 83300.0 0.45 930470.0 46000.0 0.26 0.5048 0.9646 3626553 CBKinase1_016154 NC(=O)CSc1ncnc2scc(c3ccc(Cl)cc3)c12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L21 compound treatment 868029.0 -30900.0 -0.17 871219.0 -13200.0 -0.07 -0.1722 -0.9326 3626554 CBKinase1_016155 COc1ccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccc(Cl)cc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L22 compound treatment 909402.0 10400.0 0.06 887847.0 3390.0 0.02 0.0538 0.8951 1290149 CBKinase1_016156 O=C(Cn1cnc2ccccc2c1=O)NCc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L23 mock treatment 738767.0 -160000.0 -0.87 878343.0 -6120.0 -0.03 -0.6428 -0.7344 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 L24 mock treatment 922485.0 23500.0 0.13 857174.0 -27300.0 -0.15 -0.0179 -0.0895 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M01 compound treatment 981822.0 82900.0 0.45 969129.0 84700.0 0.48 0.6573 0.9996 3626555 CBKinase1_016157 Cc1ccc(cc1C)N(CC(=O)N)S(=O)(=O)c2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M02 compound treatment 926459.0 27500.0 0.15 1009856.0 125000.0 0.71 0.6059 0.8386 3626556 CBKinase1_016158 Cn1nnc2cc(NC(=O)NCc3ccco3)ccc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M03 compound treatment 900428.0 1470.0 0.01 901682.0 17200.0 0.1 0.0743 0.7629 3626557 CBKinase1_016159 Cc1cc(C)c(c(C)c1)S(=O)(=O)NCC(=O)Nc2ccc(Br)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M04 compound treatment 912265.0 13300.0 0.07 927074.0 42600.0 0.24 0.2212 0.8815 1911042 CBKinase1_016160 COC(=O)c1ccccc1NC(=O)Cn2c(nc3ccccc23)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M05 compound treatment 908609.0 9650.0 0.05 929833.0 45400.0 0.26 0.2181 0.8352 3626558 CBKinase1_016161 COC(=O)c1ccc(cc1)n2c(CCC(=O)O)ccc2c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M06 compound treatment 922662.0 23700.0 0.13 857924.0 -26500.0 -0.15 -0.0143 -0.0721 3626559 CBKinase1_016162 Cc1cc(C)c(NC(=O)CSc2nnc(c3ccccc3)n2c4ccc(F)cc4)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M07 compound treatment 999364.0 100000.0 0.55 886134.0 1680.0 0.01 0.3943 0.7192 2068670 CBKinase1_016163 Cc1cc(C)nc(SCCS(=O)(=O)Cc2ccc(Cl)cc2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M08 compound treatment 993282.0 94300.0 0.51 955198.0 70700.0 0.4 0.6461 0.992 3626560 CBKinase1_016164 COc1cccc(OCC(=O)Nc2ccccc2C(=O)Nc3ccc(cc3)C(=O)O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M09 mock treatment 947144.0 48200.0 0.26 881841.0 -2620.0 -0.01 0.1756 0.6664 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M10 mock treatment 998870.0 99900.0 0.55 922189.0 37700.0 0.21 0.5361 0.9157 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M11 compound treatment 989198.0 90200.0 0.49 851936.0 -32500.0 -0.18 0.2187 0.4161 3626561 CBKinase1_016165 CC(C)OC(=O)C1C2OC3(CN(Cc4ccco4)C(=O)C13)C=C2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M12 compound treatment 942919.0 44000.0 0.24 878980.0 -5480.0 -0.03 0.1479 0.6111 3626562 CBKinase1_016166 Cc1cc(C)c(NC(=O)CN(c2ccc(C)c(C)c2)S(=O)(=O)C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M13 mock treatment 1028484.0 130000.0 0.71 841461.0 -43000.0 -0.24 0.3287 0.4397 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M14 mock treatment 954494.0 55500.0 0.3 967083.0 82600.0 0.47 0.5437 0.9784 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M15 compound treatment 971302.0 72300.0 0.39 943760.0 59300.0 0.33 0.5156 0.9966 3626563 CBKinase1_016167 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)NC2CCCC2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M16 compound treatment 999527.0 101000.0 0.55 867129.0 -17300.0 -0.1 0.3192 0.5723 3626564 CBKinase1_016168 Cc1ccc(NC(=O)CSc2nnc(c3ccccc3)n2c4ccccc4)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M17 compound treatment 956244.0 57300.0 0.31 965079.0 80600.0 0.45 0.5425 0.9834 3626565 CBKinase1_016169 CS(=O)(=O)N(CC(=O)Nc1ccccc1c2ccccc2)c3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M18 compound treatment 944158.0 45200.0 0.25 868448.0 -16000.0 -0.09 0.1107 0.4212 3626566 CBKinase1_016170 Cc1ccc(cc1CNC(=O)CN2CCOCC2)c3nn(C)c(=O)c4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M19 compound treatment 1039248.0 140000.0 0.77 892869.0 8410.0 0.05 0.5751 0.7494 3626567 CBKinase1_016171 COC(=O)c1c(C)c(C)sc1NC(=O)CSc2nnc3ccccn23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M20 compound treatment 969549.0 70600.0 0.39 905530.0 21100.0 0.12 0.3565 0.884 3626568 CBKinase1_016172 Cc1nn(Cc2ccc(Cl)cc2)c(C)c1NC(=O)c3nc4nc(C)cc(C(F)F)n4n3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M21 compound treatment 920483.0 21500.0 0.12 847140.0 -37300.0 -0.21 -0.0656 -0.2725 3626569 CBKinase1_016173 Cc1ccc(cc1)S(=O)(=O)NCC(=O)Nc2ccc(cc2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M22 compound treatment 891120.0 -7840.0 -0.04 839517.0 -44900.0 -0.25 -0.2094 -0.815 3626570 CBKinase1_016174 Cc1cc(C)c2c(O)nc(SCC(=O)c3ccc(F)c(C)c3)nc2n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M23 compound treatment 930823.0 31900.0 0.17 972341.0 87900.0 0.5 0.4733 0.9015 1631557 CBKinase1_016175 CC(C)(C)c1ccc(cc1)S(=O)(=O)CC(O)CSc2nc3CCCCc3cc2C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 M24 compound treatment 1003408.0 104000.0 0.57 862527.0 -21900.0 -0.12 0.3158 0.5413 3626571 CBKinase1_016176 OC1=C(C(N(Cc2ccco2)C1=O)c3ccc(Cl)cc3)C(=O)c4cc5ccccc5o4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N01 compound treatment 957206.0 58200.0 0.32 992150.0 108000.0 0.61 0.6541 0.9545 3626572 CBKinase1_016177 OC1=C(C(N(CCCN2CCOCC2)C1=O)c3ccc(F)cc3)C(=O)c4cc5ccccc5o4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N02 compound treatment 946425.0 47500.0 0.26 972107.0 87600.0 0.49 0.5326 0.9547 3626573 CBKinase1_016178 COc1ccc(OCC(=O)Nc2ccc3C(=O)NC(=O)c3c2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N03 compound treatment 970112.0 71200.0 0.39 962953.0 78500.0 0.44 0.5875 0.9979 3626574 CBKinase1_016179 Cc1ccc(cc1)n2c3CCCC(=O)c3cc(C(=O)NCCCN4CCOCC4)c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N04 compound treatment 1027300.0 128000.0 0.7 947282.0 62800.0 0.35 0.7458 0.95 1338234 CBKinase1_016180 CCOC(=O)c1sc2ncn(CC(=O)Nc3ccccc3Cl)c(=O)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N05 compound treatment 928363.0 29400.0 0.16 954054.0 69600.0 0.39 0.3909 0.9222 1474987 CBKinase1_016181 COC(=O)c1ccc(NC(=O)c2c(NCc3cccnc3)sc4CCCCc24)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N06 compound treatment 1016562.0 118000.0 0.64 987475.0 103000.0 0.58 0.8646 0.9987 3626575 CBKinase1_016182 Cc1cc(C)c(OCC(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N07 compound treatment 997188.0 98200.0 0.54 981171.0 96700.0 0.55 0.7647 1.0 3626576 CBKinase1_016183 Cc1ccnc(NC(c2ccc3ccc(C)nc3c2O)c4c(F)cccc4Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N08 compound treatment 1011464.0 113000.0 0.61 1013233.0 129000.0 0.73 0.9476 0.9965 3626577 CBKinase1_016184 COc1ccc(C)cc1NC(=O)c2ccc(OCC(=O)Nc3cccc(c3)C(F)(F)F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N09 mock treatment 1025562.0 127000.0 0.69 1009207.0 125000.0 0.7 0.9859 1.0 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N10 mock treatment 1013400.0 114000.0 0.62 861098.0 -23400.0 -0.13 0.3487 0.5461 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N11 compound treatment 918673.0 19700.0 0.11 913689.0 29200.0 0.16 0.1926 0.9787 3626578 CBKinase1_016185 Cc1ccccc1NC(=O)CSc2nnc(c3cccc(Cl)c3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N12 compound treatment 1036402.0 137000.0 0.75 1001253.0 117000.0 0.66 0.9961 0.9979 3626579 CBKinase1_016186 COc1ccc(cc1)n2c(SCC(=O)Nc3cccc(C)c3C)nnc2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N13 mock treatment 1019986.0 121000.0 0.66 901900.0 17400.0 0.1 0.5367 0.8035 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N14 mock treatment 996315.0 97400.0 0.53 1071418.0 187000.0 1.05 1.121 0.9498 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N15 compound treatment 987481.0 88500.0 0.48 926515.0 42100.0 0.24 0.5093 0.9462 3626580 CBKinase1_016187 CCC(=O)Nc1ccc(Cl)c(NC(=O)COc2cccc3ccccc23)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N16 compound treatment 1032940.0 134000.0 0.73 930838.0 46400.0 0.26 0.7021 0.9038 3626581 CBKinase1_016188 NC(=O)C1CCN(CC1)C(=O)CSc2nc3ccccc3[nH]2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N17 compound treatment 905296.0 6340.0 0.03 1003497.0 119000.0 0.67 0.4989 0.7426 3626582 CBKinase1_016189 CS(=O)(=O)N(CC(=O)NC1CCCCC1)c2cccc(F)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N18 compound treatment 1042266.0 143000.0 0.78 988543.0 104000.0 0.59 0.9681 0.9899 3626583 CBKinase1_016190 OC(=O)CNS(=O)(=O)c1ccc(cc1)c2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N19 compound treatment 943091.0 44100.0 0.24 1017159.0 133000.0 0.75 0.6992 0.8899 3626584 CBKinase1_016191 NC(=O)c1c(NC(=O)COc2ccc(Br)cc2Cl)sc3CCCCc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N20 compound treatment 956601.0 57600.0 0.31 996155.0 112000.0 0.63 0.6677 0.9486 3626585 CBKinase1_016192 OC(=O)c1cc(O)ccc1NC(=O)COc2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N21 compound treatment 975418.0 76500.0 0.42 920297.0 35800.0 0.2 0.438 0.9445 1682750 CBKinase1_016193 COc1ccccc1NC(=O)c2c(NCc3ccc(C)o3)sc4CCCc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N22 compound treatment 978675.0 79700.0 0.44 938897.0 54400.0 0.31 0.5247 0.9854 3626586 CBKinase1_016194 CC(C)(C)c1ccc(cc1)S(=O)(=O)CCSc2nc3ccccc3o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N23 compound treatment 979744.0 80800.0 0.44 963976.0 79500.0 0.45 0.6288 1.0 3626587 CBKinase1_016195 COc1ccc(NC(=O)CN(c2cccc(F)c2)S(=O)(=O)C)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 N24 compound treatment 1019171.0 120000.0 0.66 1010000.0 126000.0 0.71 0.9644 0.9993 3626588 CBKinase1_016196 Cc1ccc(cc1C)N(CC(=O)Nc2ccccc2c3ccccc3)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O01 compound treatment 948199.0 49200.0 0.27 982783.0 98300.0 0.55 0.582 0.9448 3626589 CBKinase1_016197 OC(=O)CC(N1CCOCC1)C(=O)OC2CCCCC2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O02 compound treatment 959645.0 60700.0 0.33 918471.0 34000.0 0.19 0.3698 0.9662 3626590 CBKinase1_016198 Cc1sc2ncnc(SCC(=O)Nc3ccc(F)cc3)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O03 compound treatment 1172299.0 273000.0 1.49 975744.0 91300.0 0.51 1.419 0.899 3626591 CBKinase1_016199 COC(=O)c1ccc(NC(=O)CSc2ncnc3sc(C)c(C)c23)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O04 compound treatment 992669.0 93700.0 0.51 956038.0 71600.0 0.4 0.647 0.9931 3626592 CBKinase1_016200 COc1cc(CO)cc(Br)c1OCc2cccc(c2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O05 compound treatment 1017206.0 118000.0 0.65 941975.0 57500.0 0.32 0.6857 0.9492 3626593 CBKinase1_016201 NC(=O)C1CCN(CC1)C(=O)CSc2nc3ccccc3o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O06 compound treatment 1016443.0 117000.0 0.64 952818.0 68400.0 0.39 0.726 0.9703 3626594 CBKinase1_016202 COc1ccc(cc1)n2c(SCC(=O)N3CCOCC3)nnc2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O07 compound treatment 1041967.0 143000.0 0.78 997168.0 113000.0 0.64 1.0013 0.9948 2085432 CBKinase1_016203 CN(CC(=O)O)S(=O)(=O)c1ccc(F)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O08 compound treatment 979911.0 81000.0 0.44 934042.0 49600.0 0.28 0.5101 0.9756 3626595 CBKinase1_016204 CCc1ccc(cc1)n2c(C)nnc2SCC(=O)Nc3ccc(OC)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O09 compound treatment 1042299.0 143000.0 0.78 971149.0 86700.0 0.49 0.8989 0.9743 3626596 CBKinase1_016205 Cc1sc2ncnc(SCC(=O)Nc3cccc(c3)C(F)(F)F)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O10 compound treatment 973294.0 74300.0 0.41 975600.0 91100.0 0.51 0.6502 0.9932 3626597 CBKinase1_016206 Cc1cc(C)cc(NC(=O)CSc2nnc(c3ccncc3)n2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O11 mock treatment 984633.0 85700.0 0.47 989752.0 105000.0 0.59 0.7504 0.9931 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O12 mock treatment 992643.0 93700.0 0.51 998021.0 114000.0 0.64 0.8143 0.9938 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O13 compound treatment 1065163.0 166000.0 0.91 1036796.0 152000.0 0.86 1.2488 0.9996 3626598 CBKinase1_016207 COc1ccc(NC(=O)COc2ccc(cc2Br)C(C)C)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O14 compound treatment 1019913.0 121000.0 0.66 992166.0 108000.0 0.61 0.8962 0.9991 3626599 CBKinase1_016208 CCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2cccnc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O15 compound treatment 1053358.0 154000.0 0.84 1069421.0 185000.0 1.04 1.3332 0.9944 3626600 CBKinase1_016209 Cc1nnc(SCC(=O)Nc2ccc(Br)cc2Cl)n1c3cccc(C)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O16 compound treatment 1019462.0 121000.0 0.66 991476.0 107000.0 0.6 0.8917 0.9991 3626601 CBKinase1_016210 Cc1cc(C)c(NC(=O)CN(c2ccc(Br)cc2)S(=O)(=O)C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O17 compound treatment 1067981.0 169000.0 0.92 1045303.0 161000.0 0.91 1.2936 1.0 1860803 CBKinase1_016211 CCc1ccc(OCC(=O)Nc2sc3CCCc3c2C(=O)OC)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O18 compound treatment 988283.0 89300.0 0.49 1008663.0 124000.0 0.7 0.8398 0.9844 3626602 CBKinase1_016212 COc1ccc(cc1OC)S(=O)(=O)N(C)CC(=O)Nc2ccc(Br)cc2F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O19 compound treatment 979389.0 80400.0 0.44 952920.0 68500.0 0.39 0.5833 0.9979 3626603 CBKinase1_016213 COc1ccc(OC)c(c1)S(=O)(=O)Nc2ccc(cc2)C(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O20 compound treatment 947225.0 48300.0 0.26 934551.0 50100.0 0.28 0.386 0.9994 3626604 CBKinase1_016214 Cn1c(SCC(=O)Nc2c(Cl)cc(Cl)cc2Cl)nnc1c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O21 compound treatment 1005317.0 106000.0 0.58 991018.0 107000.0 0.6 0.8353 0.9999 3626605 CBKinase1_016215 Fc1ccc(NC(=O)CCN2C(=O)c3ccccc3S2(=O)=O)c(F)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O22 compound treatment 950311.0 51400.0 0.28 943529.0 59100.0 0.33 0.4337 0.9963 3626606 CBKinase1_016216 CC(=O)CSc1ncnc2scc(c3ccc(F)cc3)c12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O23 compound treatment 927669.0 28700.0 0.16 925645.0 41200.0 0.23 0.275 0.9817 3626607 CBKinase1_016217 Brc1ccc(cc1)c2csc3ncnc(SCC(=O)N4CCOCC4)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 O24 compound treatment 995778.0 96800.0 0.53 886958.0 2500.0 0.01 0.3837 0.7257 3626608 CBKinase1_016218 CCOc1ccc(OCC(=O)Nc2sc3CC(C)CCc3c2C(=O)N)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P01 compound treatment 939201.0 40200.0 0.22 823449.0 -61000.0 -0.34 -0.0878 -0.2152 3626609 CBKinase1_016219 OC1=C(C(N(Cc2ccco2)C1=O)c3cccnc3)C(=O)c4cc5ccccc5o4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P02 compound treatment 914253.0 15300.0 0.08 850744.0 -33700.0 -0.19 -0.0753 -0.3629 3626610 CBKinase1_016220 COc1ccc(C)cc1NC(=O)CSc2nc3ccccc3s2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P03 compound treatment 905868.0 6910.0 0.04 908385.0 23900.0 0.13 0.122 0.8714 3626611 CBKinase1_016221 CCn1c(SCC(=O)Nc2ccc(Br)cc2F)nnc1c3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P04 compound treatment 911039.0 12100.0 0.07 887489.0 3030.0 0.02 0.0587 0.8618 3626612 CBKinase1_016222 Cc1cc(C)c(NC(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P05 compound treatment 945333.0 46400.0 0.25 930129.0 45700.0 0.26 0.361 1.0 1700276 CBKinase1_016223 Clc1ccccc1NC(=O)CN2C(=O)c3ccccc3S2(=O)=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P06 compound treatment 955519.0 56600.0 0.31 605295.0 -279000.0 -1.57 -0.8943 -0.5577 3626613 CBKinase1_016224 Cc1ccc(NC(=O)c2ccco2)c(NC(=O)COc3ccccc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P07 compound treatment 876285.0 -22700.0 -0.12 964349.0 79900.0 0.45 0.2309 0.4944 3626614 CBKinase1_016225 CCc1ccc(cc1)C(Nc2cc(C)ccn2)c3ccc4ccc(C)nc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P08 compound treatment 916593.0 17600.0 0.1 862616.0 -21800.0 -0.12 -0.019 -0.1215 1241787 CBKinase1_016226 COC(=O)c1sc(c(C(=O)OC)c1C)S(=O)(=O)NCc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P09 compound treatment 1001650.0 103000.0 0.56 1007125.0 123000.0 0.69 0.8853 0.9946 3626615 CBKinase1_016227 CN(C(=O)CSc1nnc(c2ccc(Cl)cc2)n1c3ccccc3)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P10 compound treatment 892139.0 -6820.0 -0.04 894577.0 10100.0 0.06 0.014 0.2055 3626616 CBKinase1_016228 COc1ccc(cc1NC(=O)COc2ccc(Br)cc2Cl)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P11 mock treatment 956290.0 57300.0 0.31 1021227.0 137000.0 0.77 0.7664 0.9212 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P12 mock treatment 1020290.0 121000.0 0.66 974617.0 90200.0 0.51 0.8277 0.9914 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P13 compound treatment 976795.0 77800.0 0.42 1014549.0 130000.0 0.73 0.819 0.9663 3626617 CBKinase1_016229 CNC(=O)CN(c1ccc2OCCOc2c1)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P14 compound treatment 904322.0 5360.0 0.03 966544.0 82100.0 0.46 0.3479 0.7503 3626618 CBKinase1_016230 CC(=O)Oc1ccc(NC(=O)COc2cccc(C)c2C)c(c1)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P15 compound treatment 998117.0 99200.0 0.54 1013114.0 129000.0 0.73 0.8956 0.9896 3626619 CBKinase1_016231 Cn1c(SCC(=O)Nc2ccc(Oc3ccc(Cl)cc3)cc2)nnc1c4ccccc4O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P16 compound treatment 981364.0 82400.0 0.45 1019363.0 135000.0 0.76 0.8558 0.9686 3626620 CBKinase1_016232 COc1ccc2sc(SCc3nc(N)nc(Nc4cccc(C)c4C)n3)nc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P17 compound treatment 1062865.0 164000.0 0.89 1005290.0 121000.0 0.68 1.1143 0.9909 3626621 CBKinase1_016233 COc1ccc(cc1NC(=O)CN(c2ccc(Cl)c(Cl)c2)S(=O)(=O)C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P18 compound treatment 989735.0 90800.0 0.5 980748.0 96300.0 0.54 0.7342 0.999 1985820 CBKinase1_016234 CCOc1cccc2c(C)nc(Nc3nc(=O)c4CCCCc4[nH]3)nc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P19 compound treatment 957556.0 58600.0 0.32 965279.0 80800.0 0.46 0.5483 0.985 3626622 CBKinase1_016235 CC(Oc1ccc2c(=O)c(c3ccc(Cl)cc3)c(oc2c1)C(F)(F)F)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P20 compound treatment 874792.0 -24200.0 -0.13 786321.0 -98100.0 -0.55 -0.4844 -0.8519 3626623 CBKinase1_016236 COc1cccc(NC(=O)c2ccc(NCc3cccnc3)c(c2)[N+](=O)[O-])c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P21 compound treatment 967448.0 68500.0 0.37 1000009.0 116000.0 0.65 0.7249 0.9653 3626624 CBKinase1_016237 CCn1c(SCC(=O)N2c3ccccc3Sc4ccccc24)nnc1c5ccco5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P22 compound treatment 948928.0 50000.0 0.27 928329.0 43900.0 0.25 0.3677 0.9988 3626625 CBKinase1_016238 CCn1c(SCC(=O)Nc2cccc(OC)c2)nc3scc(c4ccccc4)c3c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P23 compound treatment 928304.0 29300.0 0.16 927917.0 43500.0 0.24 0.2865 0.9788 3626626 CBKinase1_016239 Cn1c(=O)n(CC(=O)Nc2ccccc2[N+](=O)[O-])c3ccccc3c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2374 P24 compound treatment 931245.0 32300.0 0.18 950479.0 66000.0 0.37 0.3878 0.9417 3626627 CBKinase1_016240 CS(=O)(=O)N(CC(=O)Nc1ccccc1c2ccccc2)c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A01 compound treatment 831801.0 -83500.0 -0.46 769105.0 -123000.0 -0.69 -0.8114 -0.9795 3626628 CBKinase1_016241 CCOc1ccc(NC(=O)C(C)Sc2nc3ccccc3c(=O)n2c4cccc(C)c4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A02 compound treatment 867045.0 -48300.0 -0.26 849410.0 -42400.0 -0.24 -0.3553 -0.9988 3626629 CBKinase1_016242 CC(Sc1nc(N)cc(N)n1)C(=O)Nc2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A03 compound treatment 920234.0 4930.0 0.03 1005727.0 114000.0 0.64 0.473 0.7361 3626630 CBKinase1_016243 Clc1ccc(NC(=O)CSc2nnc(c3cccc(Br)c3)n2c4ccccc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A04 compound treatment 999544.0 84200.0 0.46 925576.0 33800.0 0.19 0.4598 0.9237 3626631 CBKinase1_016244 CC(=O)Nc1ccc(NC(=O)CC2Nc3ccccc3NC2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A05 compound treatment 928198.0 12900.0 0.07 730886.0 -161000.0 -0.91 -0.5916 -0.6503 3626632 CBKinase1_016245 CCc1cccc(C)c1NC(=O)CSc2nc3ccccc3c(=O)n2c4cccc5ccccc45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A06 compound treatment 844202.0 -71100.0 -0.39 849197.0 -42600.0 -0.24 -0.4443 -0.9734 3626633 CBKinase1_016246 OC1=C(C(N(CCCN2CCOCC2)C1=O)c3cccnc3)C(=O)c4cc5ccccc5o4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A07 compound treatment 910084.0 -5220.0 -0.03 822671.0 -69100.0 -0.39 -0.2957 -0.7568 3626634 CBKinase1_016247 COC(=O)c1ccccc1NC(=O)CSc2nnc(c3cccnc3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A08 compound treatment 992327.0 77000.0 0.42 743691.0 -148000.0 -0.83 -0.293 -0.3134 3626635 CBKinase1_016248 Cc1ccccc1c2nnc(SCC(=O)Nc3ccc(Br)cc3F)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A09 compound treatment 938667.0 23400.0 0.13 900204.0 8390.0 0.05 0.1236 0.9088 3626636 CBKinase1_016249 CCc1ccccc1NC(=O)CSc2nc3ccccc3c(=O)n2c4ccccc4Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A10 compound treatment 863498.0 -51800.0 -0.28 923197.0 31400.0 0.18 -0.0749 -0.2246 3626637 CBKinase1_016250 Cc1cccc(NC(=O)CSc2nnc([nH]2)c3ccccc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A11 compound treatment 928879.0 13600.0 0.07 805074.0 -86700.0 -0.49 -0.2933 -0.5931 3626638 CBKinase1_016251 Cc1ccc(cc1)c2nn(CCC(=O)Nc3cccc(Cl)c3)c(=O)c4ccccc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A12 compound treatment 850154.0 -65200.0 -0.36 936076.0 44300.0 0.25 -0.0751 -0.1729 3626639 CBKinase1_016252 CCOc1ccc(cc1)C(=O)CSc2nnc(c3ccncc3)n2c4ccc(C)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A13 mock treatment 953355.0 38100.0 0.21 974530.0 82700.0 0.47 0.4766 0.9337 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A14 mock treatment 1020648.0 105000.0 0.58 878609.0 -13200.0 -0.07 0.354 0.6105 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A15 compound treatment 1001617.0 86300.0 0.47 1001193.0 109000.0 0.62 0.7691 0.9912 3626640 CBKinase1_016253 COc1ccc(NC(=O)c2c(NCc3ccc(C)o3)sc4CC(C)CCc24)c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A16 compound treatment 951765.0 36500.0 0.2 937125.0 45300.0 0.26 0.3213 0.9924 3626641 CBKinase1_016254 Cc1c(CC(=O)O)c(=O)oc2cc(OCC(=O)O)ccc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A17 compound treatment 992757.0 77500.0 0.42 978620.0 86800.0 0.49 0.645 0.9974 3626642 CBKinase1_016255 CNC(=O)CN(c1ccc(F)cc1)S(=O)(=O)c2ccc3OCCOc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A18 compound treatment 1006646.0 91300.0 0.5 848869.0 -42900.0 -0.24 0.1815 0.3274 3626643 CBKinase1_016256 COc1ccc(cc1NC(=S)NC(=O)COc2ccc(Br)cc2Cl)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A19 compound treatment 986123.0 70800.0 0.39 844847.0 -47000.0 -0.26 0.0862 0.184 3626644 CBKinase1_016257 Cc1nonc1OCCNc2ccc(cc2[N+](=O)[O-])C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A20 compound treatment 1094758.0 179000.0 0.98 1088514.0 197000.0 1.11 1.4767 0.9981 3626645 CBKinase1_016258 COc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc(F)cc2)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A21 compound treatment 998732.0 83400.0 0.46 805120.0 -86700.0 -0.49 -0.0235 -0.0351 3626646 CBKinase1_016259 Cc1ccc(NC(=O)CN(c2cccc(F)c2)S(=O)(=O)C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A22 compound treatment 815952.0 -99400.0 -0.54 811968.0 -79800.0 -0.45 -0.7018 -0.9957 3626647 CBKinase1_016260 CC(=O)c1cccc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A23 compound treatment 875742.0 -39600.0 -0.22 831620.0 -60200.0 -0.34 -0.3926 -0.9762 3626648 CBKinase1_016261 Cc1ccc(NC(=O)CSc2ncnc3sc4CCCc4c23)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 A24 compound treatment 733606.0 -182000.0 -0.99 760506.0 -131000.0 -0.74 -1.2248 -0.9896 3626649 CBKinase1_016262 CN(C)c1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2c4ccc(Cl)cc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B01 compound treatment 913699.0 -1610.0 -0.01 645201.0 -247000.0 -1.39 -0.9891 -0.7116 3626650 CBKinase1_016263 Cc1ccc(o1)C(=O)CC2(O)C(=O)N(CCCC#N)c3ccccc32 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B02 compound treatment 952043.0 36700.0 0.2 682878.0 -209000.0 -1.18 -0.6909 -0.5783 3626651 CBKinase1_016264 CCn1c(SCC(=O)Nc2cccc(c2)C(=O)O)nnc1c3ccc(Cl)cc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B03 compound treatment 961064.0 45800.0 0.25 897298.0 5480.0 0.03 0.1985 0.7886 3626652 CBKinase1_016265 COc1ccc(NC(=O)Cn2cnc3sc(cc3c2=O)c4ccccc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B04 compound treatment 928759.0 13500.0 0.07 868026.0 -23800.0 -0.13 -0.0429 -0.2804 3626653 CBKinase1_016266 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)NC2CC2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B05 compound treatment 1150950.0 236000.0 1.29 750891.0 -141000.0 -0.79 0.348 0.2302 1652120 CBKinase1_016267 Cc1ccc2NC(=O)C(O)(CC(=O)c3ccco3)c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B06 compound treatment 985097.0 69800.0 0.38 706147.0 -186000.0 -1.05 -0.4706 -0.4225 3626654 CBKinase1_016268 COc1cccc(NC(=O)CCN2C(=O)c3ccccc3S2(=O)=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B07 compound treatment 1179485.0 264000.0 1.44 727201.0 -165000.0 -0.93 0.3638 0.2121 3626655 CBKinase1_016269 FC(F)c1cc(nc2c(cnn12)C(=O)NCCN3CCOCC3)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B08 compound treatment 863751.0 -51600.0 -0.28 898978.0 7160.0 0.04 -0.1705 -0.5995 3626656 CBKinase1_016270 CC1=CC(C)(C)N2C(=O)C(=O)c3cc(OC(=O)CN4C(=O)c5ccccc5C4=O)cc1c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B09 compound treatment 975340.0 60000.0 0.33 840779.0 -51000.0 -0.29 0.0284 0.065 3626657 CBKinase1_016271 COc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2c4ccc(C)cc4)c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B10 compound treatment 818225.0 -97100.0 -0.53 924026.0 32200.0 0.18 -0.2464 -0.4398 3626658 CBKinase1_016272 OC(=O)c1cc(Br)ccc1NC(=O)COc2ccccc2[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B11 compound treatment 933627.0 18300.0 0.1 826807.0 -65000.0 -0.37 -0.1884 -0.4959 3626659 CBKinase1_016273 CC(=O)C(Sc1cc(C)nc(N)n1)C(=O)Nc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B12 compound treatment 1038061.0 123000.0 0.67 993670.0 102000.0 0.57 0.8798 0.997 2085430 CBKinase1_016274 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B13 mock treatment 920554.0 5250.0 0.03 908535.0 16700.0 0.09 0.0869 0.8822 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B14 mock treatment 1052918.0 138000.0 0.75 948676.0 56900.0 0.32 0.7579 0.9279 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B15 compound treatment 877007.0 -38300.0 -0.21 938819.0 47000.0 0.26 0.0395 0.117 3626660 CBKinase1_016275 OC(COc1ccc2ccccc2c1Br)Cn3ccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B16 compound treatment 1003744.0 88400.0 0.48 921887.0 30100.0 0.17 0.4613 0.9014 3626661 CBKinase1_016276 CC(=O)c1cccc(c1)n2c(CCC(=O)O)ccc2c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B17 compound treatment 1085515.0 170000.0 0.93 1006371.0 115000.0 0.65 1.1137 0.9842 3626662 CBKinase1_016277 CCOc1ccc(OCC(=O)Nc2cccc(c2)C(=O)O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B18 compound treatment 990592.0 75300.0 0.41 887310.0 -4500.0 -0.03 0.2727 0.6622 3626663 CBKinase1_016278 CS(=O)(=O)N(CC(=O)NC1CCCC1)c2cccc(F)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B19 compound treatment 962344.0 47000.0 0.26 865208.0 -26600.0 -0.15 0.0756 0.2541 3626664 CBKinase1_016279 COC(=O)CCSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4cccc(C)c4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B20 compound treatment 877390.0 -37900.0 -0.21 973651.0 81800.0 0.46 0.1798 0.3556 3626665 CBKinase1_016280 COc1ccccc1NC(=O)CSc2nnnn2c3cc(C)cc(C)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B21 compound treatment 1079794.0 164000.0 0.9 1017669.0 126000.0 0.71 1.1366 0.9932 3626666 CBKinase1_016281 COc1ccc(cc1CNC(=O)c2ccc(cc2)[N+](=O)[O-])c3nn(C)c(=O)c4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B22 compound treatment 1041560.0 126000.0 0.69 911681.0 19900.0 0.11 0.5666 0.8113 3626667 CBKinase1_016282 CC(=O)c1cccc(NC(=O)CNS(=O)(=O)c2ccc(Br)cc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B23 compound treatment 926766.0 11500.0 0.06 896006.0 4190.0 0.02 0.061 0.9113 3626668 CBKinase1_016283 COc1ccc(NC(=O)CC2Sc3ccc(cc3NC2=O)C(F)(F)F)c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 B24 compound treatment 1016916.0 102000.0 0.55 840485.0 -51300.0 -0.29 0.1877 0.3 3626669 CBKinase1_016284 COc1ccccc1N(CC(=O)Nc2c(C)cc(C)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C01 compound treatment 1009513.0 94200.0 0.51 932383.0 40600.0 0.23 0.5254 0.9334 3626670 CBKinase1_016285 Cn1nc(CC(=O)Nc2ccc(Oc3ccccc3)cc2)c4ccccc4c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C02 compound treatment 961249.0 45900.0 0.25 927292.0 35500.0 0.2 0.3188 0.9937 3626671 CBKinase1_016286 CCOc1ccc(OCC(=O)Nc2cc(C)c(Cl)cc2OC)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C03 compound treatment 822873.0 -92400.0 -0.5 732583.0 -159000.0 -0.9 -0.9915 -0.9629 3626672 CBKinase1_016287 COc1cc(cc(Cl)c1OC)C(Nc2cc(C)ccn2)c3ccc4ccc(C)nc4c3O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C04 compound treatment 881447.0 -33900.0 -0.18 969997.0 78200.0 0.44 0.1809 0.3785 3626673 CBKinase1_016288 COc1ccc(cc1OC)C(=O)NCc2nnc(S)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C05 compound treatment 1204220.0 289000.0 1.58 944606.0 52800.0 0.3 1.3257 0.8259 3626674 CBKinase1_016289 Clc1ccccc1CSc2nnc(Cn3cnc4ccccc34)n2c5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C06 compound treatment 925217.0 9910.0 0.05 908780.0 17000.0 0.1 0.1059 0.9637 1868322 CBKinase1_016290 O=C(Cc1coc2ccc3ccccc3c12)Nc4cccnc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C07 compound treatment 842412.0 -72900.0 -0.4 929322.0 37500.0 0.21 -0.1319 -0.2927 3626675 CBKinase1_016291 CCc1cccc(CC)c1NC(=O)Cn2cnc3ccccc3c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C08 compound treatment 926582.0 11300.0 0.06 995121.0 103000.0 0.58 0.4553 0.7775 3626676 CBKinase1_016292 CCOc1ccc(cc1)S(=O)(=O)NCC(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C09 compound treatment 926095.0 10800.0 0.06 912928.0 21100.0 0.12 0.1258 0.9474 3626677 CBKinase1_016293 CS(=O)(=O)N(CC(=O)N1CCOCC1)c2ccc3OCCOc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C10 compound treatment 907488.0 -7820.0 -0.04 845449.0 -46400.0 -0.26 -0.215 -0.8118 3626678 CBKinase1_016294 Cc1cccc(OCCCn2c(CO)nc3ccccc23)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C11 mock treatment 904466.0 -10800.0 -0.06 906621.0 14800.0 0.08 0.0172 0.1678 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C12 mock treatment 905933.0 -9370.0 -0.05 877932.0 -13900.0 -0.08 -0.0915 -0.9788 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C13 compound treatment 876584.0 -38700.0 -0.21 833889.0 -57900.0 -0.33 -0.3803 -0.9779 3626679 CBKinase1_016295 COc1ccc(cc1)N(CC(=O)Nc2ccccc2c3ccccc3)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C14 compound treatment 894488.0 -20800.0 -0.11 954696.0 62900.0 0.35 0.1703 0.4574 3626680 CBKinase1_016296 Cc1cc(C)c(NC(=O)CSc2nnc(o2)c3ccc(Br)cc3)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C15 mock treatment 986098.0 70800.0 0.39 1077840.0 186000.0 1.05 1.0147 0.908 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C16 mock treatment 939128.0 23800.0 0.13 807403.0 -84400.0 -0.48 -0.2445 -0.4956 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C17 compound treatment 944326.0 29000.0 0.16 866548.0 -25300.0 -0.14 0.0113 0.0532 3626681 CBKinase1_016297 Cc1cc(C)c(NC(=O)CN(c2ccc(Cl)cc2)S(=O)(=O)C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C18 compound treatment 1155340.0 240000.0 1.31 958968.0 67200.0 0.38 1.1943 0.8756 3626682 CBKinase1_016298 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)CSc4nncn4C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C19 compound treatment 1045954.0 131000.0 0.71 896887.0 5070.0 0.03 0.5246 0.7349 1615250 CBKinase1_016299 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2ccccn2)c3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C20 compound treatment 794806.0 -120000.0 -0.66 965322.0 73500.0 0.41 -0.1722 -0.2215 1670375 CBKinase1_016300 OC1(CC(=O)c2ccncc2)C(=O)N(Cc3ccccc3)c4ccc(Cl)cc41 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C21 compound treatment 841918.0 -73400.0 -0.4 905413.0 13600.0 0.08 -0.2291 -0.5616 3626683 CBKinase1_016301 CCc1ccc(OCC(=O)Nc2ccccc2C(=O)OC)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C22 compound treatment 758794.0 -157000.0 -0.85 936402.0 44600.0 0.25 -0.4265 -0.4789 2068716 CBKinase1_016302 CCn1c(SCC(=O)N)nnc1c2sc3cc(Cl)ccc3c2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C23 compound treatment 919515.0 4210.0 0.02 812763.0 -79100.0 -0.45 -0.2988 -0.6697 3626684 CBKinase1_016303 OC(=O)CCc1ccc(c2ccc(F)cc2)n1c3cccc(c3)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 C24 compound treatment 769265.0 -146000.0 -0.8 698900.0 -193000.0 -1.09 -1.3326 -0.9884 3626685 CBKinase1_016304 CCc1ccc(Oc2c(CC(=O)O)oc3cc(O)c(CC)cc3c2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D01 compound treatment 882720.0 -32600.0 -0.18 636666.0 -255000.0 -1.44 -1.1427 -0.7886 3626686 CBKinase1_016305 CN(CC(=O)Nc1ccccc1F)S(=O)(=O)c2c(C)cc(C)cc2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D02 compound treatment 873226.0 -42100.0 -0.23 550639.0 -341000.0 -1.92 -1.5222 -0.786 3626687 CBKinase1_016306 CCOC(=O)c1c(NC(=O)CSc2nnc[nH]2)sc3CCCCc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D03 compound treatment 744337.0 -171000.0 -0.93 613112.0 -279000.0 -1.57 -1.7708 -0.9691 3626688 CBKinase1_016307 COC(=O)CSc1nc(nc2CCCCc12)c3cccc(C)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D04 compound treatment 868601.0 -46700.0 -0.25 553302.0 -339000.0 -1.91 -1.5295 -0.7945 3024609 CBKinase1_016308 Cc1cc(C)nc(SCCS(=O)(=O)c2ccc(cc2)C(C)(C)C)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D05 compound treatment 860758.0 -54500.0 -0.3 698375.0 -193000.0 -1.09 -0.9815 -0.8684 3626689 CBKinase1_016309 O=C(CSC1=NC(=O)CC(N1)c2ccccc2)Nc3ccc4ccccc4c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D06 compound treatment 847971.0 -67300.0 -0.37 842725.0 -49100.0 -0.28 -0.4556 -0.9902 3626690 CBKinase1_016310 Cc1cc(I)ccc1NC(=O)CN(c2cccc(c2)C(F)(F)F)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D07 compound treatment 993616.0 78300.0 0.43 832656.0 -59200.0 -0.33 0.0665 0.1227 3626691 CBKinase1_016311 CC1CCc2c(C1)sc3nnn(CC(=O)Nc4cc(Cl)ccc4Cl)c(=O)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D08 compound treatment 957082.0 41800.0 0.23 851115.0 -40700.0 -0.23 -9.0E-4 -0.0029 3626692 CBKinase1_016312 CSc1cccc(NC(=O)CNS(=O)(=O)c2ccc(F)cc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D09 compound treatment 835484.0 -79800.0 -0.44 956152.0 64300.0 0.36 -0.0517 -0.0912 3626693 CBKinase1_016313 Clc1ccccc1C(=O)Nc2ccc(I)cc2C(=O)NCc3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D10 compound treatment 898462.0 -16800.0 -0.09 907308.0 15500.0 0.09 -0.0033 -0.0258 3626694 CBKinase1_016314 CCCn1nnc(NC(=O)COc2ccc(Cl)c(C)c2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D11 mock treatment 926055.0 10800.0 0.06 896175.0 4360.0 0.02 0.0589 0.9254 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D12 mock treatment 944388.0 29100.0 0.16 893421.0 1610.0 0.01 0.1187 0.7462 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D13 compound treatment 881910.0 -33400.0 -0.18 911538.0 19700.0 0.11 -0.0503 -0.2356 3626695 CBKinase1_016315 Clc1ccc(cc1)n2c(SCC(=O)Nc3ccc4cn[nH]c4c3)nnc2c5ccncc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D14 compound treatment 895629.0 -19700.0 -0.11 863507.0 -28300.0 -0.16 -0.1888 -0.9815 3626696 CBKinase1_016316 COc1ccc(cc1NC(=O)CN(c2cc(C)ccc2C)S(=O)(=O)C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D15 mock treatment 892525.0 -22800.0 -0.12 888639.0 -3180.0 -0.02 -0.1006 -0.8006 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D16 mock treatment 961675.0 46400.0 0.25 916286.0 24500.0 0.14 0.2765 0.9592 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D17 compound treatment 1058908.0 144000.0 0.78 1092097.0 200000.0 1.13 1.3526 0.9841 3626697 CBKinase1_016317 CCC1(C)Cc2ccccc2-c3nc(NCCCO)n(c4ccc(C)cc4)c(=O)c31 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D18 compound treatment 977902.0 62600.0 0.34 919827.0 28000.0 0.16 0.3533 0.9385 3626698 CBKinase1_016318 CCn1c(SCC(=O)Nc2ccc(Cl)cc2Cl)nnc1c3cccc(C)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D19 compound treatment 998770.0 83500.0 0.46 892818.0 1000.0 0.01 0.3262 0.7158 3626699 CBKinase1_016319 CC(C)c1ccc(NC(=O)CSc2nnc(c3ccccc3C)n2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D20 compound treatment 979873.0 64600.0 0.35 946697.0 54900.0 0.31 0.468 0.9979 3626700 CBKinase1_016320 Cc1nonc1OCCNc2cc(ccc2[N+](=O)[O-])N3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D21 compound treatment 748803.0 -167000.0 -0.91 855131.0 -36700.0 -0.21 -0.789 -0.8463 3626701 CBKinase1_016321 NC(=O)CSc1nc2cc(ccc2[nH]1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D22 compound treatment 730469.0 -185000.0 -1.01 742320.0 -149000.0 -0.84 -1.3094 -0.996 3626702 CBKinase1_016322 Cc1ccc(Cl)cc1N(CC(=O)Nc2ccc(I)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D23 compound treatment 716408.0 -199000.0 -1.09 729965.0 -162000.0 -0.91 -1.4129 -0.9962 3626703 CBKinase1_016323 COc1ccc(C)cc1NC(=O)CSc2nc3ccccc3c(=O)n2c4ccc(Cl)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 D24 compound treatment 786245.0 -129000.0 -0.7 796321.0 -95500.0 -0.54 -0.8788 -0.9912 3626704 CBKinase1_016324 Cn1c(SCC(=O)Nc2cc(Cl)cc(Cl)c2)nnc1c3ccc(Cl)cc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E01 mock treatment 808133.0 -107000.0 -0.59 791653.0 -100000.0 -0.56 -0.8129 -0.9998 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E02 mock treatment 789658.0 -126000.0 -0.69 723476.0 -168000.0 -0.95 -1.156 -0.9873 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E03 compound treatment 666018.0 -249000.0 -1.36 708480.0 -183000.0 -1.03 -1.693 -0.9908 3626705 CBKinase1_016325 [O-][N+](=O)c1cccc(c1)C(=O)Nc2ccccc2C(=O)NCc3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E04 compound treatment 623757.0 -292000.0 -1.59 712889.0 -179000.0 -1.01 -1.8386 -0.9758 3626706 CBKinase1_016326 NC(=O)c1c(NC(=O)c2cnn3c(cc(nc23)c4ccccc4)C(F)F)sc5CCCCc15 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E05 compound treatment 706746.0 -209000.0 -1.14 701931.0 -190000.0 -1.07 -1.5619 -0.9995 3626707 CBKinase1_016327 COc1cc(NC(=O)COc2ccc(Cl)cc2Cl)ccc1NC(=O)c3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E06 compound treatment 679189.0 -236000.0 -1.29 702091.0 -190000.0 -1.07 -1.6677 -0.9957 3626708 CBKinase1_016328 Cc1cc(ccc1OC(=O)COc2ccccc2[N+](=O)[O-])C(=O)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E07 compound treatment 771526.0 -144000.0 -0.78 852083.0 -39700.0 -0.22 -0.7134 -0.874 1295121 CBKinase1_016329 O=C(NCCc1c[nH]c2ccccc12)Nc3cccc4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E08 compound treatment 787560.0 -128000.0 -0.7 807200.0 -84600.0 -0.48 -0.8304 -0.9828 3626709 CBKinase1_016330 Cc1cccc(NC(=O)CN2C(=O)CNC2=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E09 mock treatment 751811.0 -163000.0 -0.89 730566.0 -161000.0 -0.91 -1.2738 -1.0 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E10 mock treatment 726721.0 -189000.0 -1.03 800719.0 -91100.0 -0.51 -1.0911 -0.9484 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E11 compound treatment 737315.0 -178000.0 -0.97 811191.0 -80600.0 -0.45 -1.0084 -0.9401 1692892 CBKinase1_016331 COc1ccccc1NC(=O)C2=C(C)Nc3ncnn3C2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E12 compound treatment 990993.0 75700.0 0.41 880160.0 -11700.0 -0.07 0.2457 0.5873 3626710 CBKinase1_016332 COC(=O)c1ccccc1NC(=O)c2nc3nc(C)cc(C(F)F)n3n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E13 compound treatment 757916.0 -157000.0 -0.86 771858.0 -120000.0 -0.68 -1.0857 -0.993 3626711 CBKinase1_016333 FC(F)(F)c1cccc(NC(=O)COc2ccc(cc2)C(=O)Nc3ccccc3Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E14 compound treatment 829134.0 -86200.0 -0.47 809879.0 -81900.0 -0.46 -0.6592 -1.0 3626712 CBKinase1_016334 CCOc1ccc(cc1CSc2nc(C)cc(C)n2)C(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E15 compound treatment 706794.0 -209000.0 -1.14 852471.0 -39300.0 -0.22 -0.9618 -0.8293 3626713 CBKinase1_016335 COc1ccc(cc1Cl)N(CC(=O)Nc2c(C)cc(C)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E16 compound treatment 845557.0 -69700.0 -0.38 709385.0 -182000.0 -1.03 -0.9963 -0.9087 3119280 CBKinase1_016336 Cc1ccc(Nc2nc(=O)cc(CSc3nc4ccccc4s3)[nH]2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E17 mock treatment 724588.0 -191000.0 -1.04 838662.0 -53200.0 -0.3 -0.9481 -0.8751 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E18 mock treatment 879355.0 -35900.0 -0.2 824618.0 -67200.0 -0.38 -0.4066 -0.9532 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E19 compound treatment 694866.0 -220000.0 -1.2 662260.0 -230000.0 -1.29 -1.7659 -0.9993 3626714 CBKinase1_016337 Cc1cc(C)c(NC(=O)CN(c2cccc3ccccc23)S(=O)(=O)C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E20 compound treatment 711799.0 -204000.0 -1.11 682835.0 -209000.0 -1.18 -1.6185 -0.9996 3626715 CBKinase1_016338 CN(CC(=O)Nc1ccc(Br)cc1F)S(=O)(=O)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E21 compound treatment 549938.0 -365000.0 -1.99 687042.0 -205000.0 -1.15 -2.2266 -0.9662 3626716 CBKinase1_016339 COc1ccc(NC(=O)c2ccccc2NC(=O)COc3cccc(c3)[N+](=O)[O-])cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E22 compound treatment 412033.0 -503000.0 -2.75 672394.0 -219000.0 -1.24 -2.8174 -0.935 3626717 CBKinase1_016340 CCOC(=O)CSc1ncnc2c3cc4COC(C)(C)Cc4nc3sc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E23 compound treatment 504954.0 -410000.0 -2.24 651775.0 -240000.0 -1.35 -2.5408 -0.9708 3022759 CBKinase1_016341 O=S(CCSc1nc2ccccc2s1)Cc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 E24 compound treatment 575837.0 -339000.0 -1.85 510216.0 -382000.0 -2.15 -2.8314 -0.9973 3626718 CBKinase1_016342 COc1ccccc1NC(=O)c2ccc(OC(C)C(=O)O)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F01 mock treatment 741722.0 -174000.0 -0.95 834369.0 -57400.0 -0.32 -0.8991 -0.8977 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F02 mock treatment 795407.0 -120000.0 -0.65 711834.0 -180000.0 -1.01 -1.1802 -0.9775 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F03 compound treatment 790400.0 -125000.0 -0.68 797935.0 -93900.0 -0.53 -0.8563 -0.9921 2068800 CBKinase1_016343 COc1ccc(OC)c(NC(=O)CC2Sc3ccccc3NC2=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F04 compound treatment 711611.0 -204000.0 -1.11 747707.0 -144000.0 -0.81 -1.3607 -0.9881 3626719 CBKinase1_016344 CC(NC(=O)c1ccccc1NC(=O)C2COc3ccccc3O2)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F05 compound treatment 832877.0 -82400.0 -0.45 809016.0 -82800.0 -0.47 -0.6482 -0.9998 3626720 CBKinase1_016345 CCCCn1c2ccccc2c3nnc(SCC(=O)c4ccccc4)nc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F06 compound treatment 784787.0 -131000.0 -0.71 820309.0 -71500.0 -0.4 -0.7888 -0.9636 3626721 CBKinase1_016346 CC(=O)Nc1ccc(NC(=O)CN(c2ccc(C)cc2C)S(=O)(=O)C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F07 compound treatment 865550.0 -49800.0 -0.27 829641.0 -62200.0 -0.35 -0.4399 -0.9921 3626722 CBKinase1_016347 CCOC(=O)c1c(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)sc4CCCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F08 compound treatment 842257.0 -73000.0 -0.4 718379.0 -173000.0 -0.98 -0.9732 -0.9218 3626723 CBKinase1_016348 Cc1cccc(N(CC(=O)Nc2ccccc2c3ccccc3)S(=O)(=O)C)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F09 mock treatment 868951.0 -46400.0 -0.25 816633.0 -75200.0 -0.42 -0.4786 -0.9696 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F10 mock treatment 919762.0 4460.0 0.02 941432.0 49600.0 0.28 0.215 0.7657 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F11 compound treatment 950296.0 35000.0 0.19 814210.0 -77600.0 -0.44 -0.1742 -0.365 3626724 CBKinase1_016349 Cc1cc(C)cc(NC(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F12 compound treatment 993612.0 78300.0 0.43 978215.0 86400.0 0.49 0.6467 0.9979 3626725 CBKinase1_016350 Cc1cccc(c1)n2c(SCC(=O)N3CCOCC3)nnc2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F13 compound treatment 896761.0 -18500.0 -0.1 818515.0 -73300.0 -0.41 -0.3637 -0.8551 3626726 CBKinase1_016351 CC(C)Cc1nnc(SC(C)C(=O)Nc2ccc(Cl)cc2)[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F14 compound treatment 917118.0 1810.0 0.01 1271864.0 380000.0 2.14 1.5217 0.7104 3626727 CBKinase1_016352 COc1ccc(cc1)n2c(SCC(=O)Nc3ccc(C)c(Cl)c3)nnc2c4ccncc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F15 compound treatment 740567.0 -175000.0 -0.95 818316.0 -73500.0 -0.41 -0.9675 -0.9302 3626728 CBKinase1_016353 O=C(CCn1nc(c2ccccc2)c3ccccc3c1=O)Nc4cccnc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F16 compound treatment 990442.0 75100.0 0.41 819046.0 -72800.0 -0.41 0.0 1.0E-4 3626729 CBKinase1_016354 Cc1ccc(NC(=O)CSc2nnc(c3ccncc3)n2C)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F17 mock treatment 775981.0 -139000.0 -0.76 974160.0 82300.0 0.46 -0.2097 -0.2353 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F18 mock treatment 885257.0 -30000.0 -0.16 706010.0 -186000.0 -1.05 -0.8565 -0.808 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F19 compound treatment 811366.0 -104000.0 -0.57 617811.0 -274000.0 -1.54 -1.4933 -0.9076 3626730 CBKinase1_016355 COc1ccccc1CCNC(=O)c2cnn3c(cc(C)nc23)C(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F20 compound treatment 672889.0 -242000.0 -1.32 734852.0 -157000.0 -0.88 -1.5614 -0.9808 3626731 CBKinase1_016356 COc1cc(CO)ccc1OCc2cccc(c2)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F21 compound treatment 623083.0 -292000.0 -1.6 792718.0 -99100.0 -0.56 -1.5231 -0.901 3626732 CBKinase1_016357 CC(O)c1nc2ccccc2n1CCCOc3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F22 compound treatment 626363.0 -289000.0 -1.58 646132.0 -246000.0 -1.38 -2.0946 -0.9979 3626733 CBKinase1_016358 Cc1cccc(c1)N(CC(=O)Nc2ccc(I)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F23 compound treatment 728520.0 -187000.0 -1.02 681521.0 -210000.0 -1.19 -1.5592 -0.9972 3626734 CBKinase1_016359 Cc1ccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccc(Cl)cc4)cc1F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 F24 compound treatment 672676.0 -243000.0 -1.32 320626.0 -571000.0 -3.22 -3.2132 -0.923 3626735 CBKinase1_016360 Cc1nnc(SCC(=O)Nc2cc(Cl)ccc2C)n1c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G01 compound treatment 767113.0 -148000.0 -0.81 856449.0 -35400.0 -0.2 -0.713 -0.8557 3626736 CBKinase1_016361 COc1ccc(cc1)c2nnc(SCC(=O)NC(C)(C)C)n2c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G02 compound treatment 848575.0 -66700.0 -0.36 793600.0 -98200.0 -0.55 -0.649 -0.9794 3626737 CBKinase1_016362 Cc1c(NC2=NC(=O)C(CC(=O)Nc3ccccc3)S2)c(=O)n(c4ccccc4)n1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G03 mock treatment 791425.0 -124000.0 -0.68 850918.0 -40900.0 -0.23 -0.6412 -0.8974 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G04 mock treatment 806779.0 -109000.0 -0.59 807884.0 -83900.0 -0.47 -0.7535 -0.9938 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G05 compound treatment 784650.0 -131000.0 -0.71 817854.0 -74000.0 -0.42 -0.7992 -0.9673 3626738 CBKinase1_016363 CC(=O)c1ccc(NC(=O)CSc2nc3cc(C)c(C)cc3[nH]2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G06 compound treatment 775404.0 -140000.0 -0.76 817693.0 -74100.0 -0.42 -0.8355 -0.9597 3626739 CBKinase1_016364 Cc1ccccc1c2nnc(SCC(=O)Nc3ccc(Br)c(C)c3C)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G07 compound treatment 773115.0 -142000.0 -0.78 823507.0 -68300.0 -0.39 -0.8212 -0.9477 3626740 CBKinase1_016365 COC(=O)c1cc(OC)c(OC)cc1NC(=O)C(C)Oc2cccc(Cl)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G08 compound treatment 834215.0 -81100.0 -0.44 876913.0 -14900.0 -0.08 -0.3724 -0.8265 3626741 CBKinase1_016366 CCc1nnc(SCC(=O)N2CCCc3ccccc23)[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G09 compound treatment 819278.0 -96000.0 -0.52 835085.0 -56700.0 -0.32 -0.5968 -0.9719 3626742 CBKinase1_016367 COc1ccc(cc1)C(=O)CSc2nnc(c3ccccc3O)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G10 compound treatment 819202.0 -96100.0 -0.52 941742.0 49900.0 0.28 -0.172 -0.2889 3626743 CBKinase1_016368 Cn1nc(c2ccc(NCCN3CCOCC3)c(c2)[N+](=O)[O-])c4ccccc4c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G11 compound treatment 916655.0 1350.0 0.01 917591.0 25800.0 0.15 0.1079 0.742 3118846 CBKinase1_016369 CCN(CC)C(=O)CSc1nc(O)c2c(C)cc(C)nc2n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G12 compound treatment 886187.0 -29100.0 -0.16 873015.0 -18800.0 -0.11 -0.1873 -0.9806 3626744 CBKinase1_016370 Cc1ccc(NC(=O)CSc2nnc(c3cccnc3)n2c4ccc(Br)cc4)cc1F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G13 compound treatment 866246.0 -49100.0 -0.27 909244.0 17400.0 0.1 -0.1199 -0.4204 3626745 CBKinase1_016371 CCCn1nnc(NC(=O)COc2ccc(C)cc2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G14 compound treatment 862053.0 -53300.0 -0.29 874636.0 -17200.0 -0.1 -0.274 -0.8943 3626746 CBKinase1_016372 COc1ccccc1NC(=O)CSc2nc(O)c3c(C)cc(C)nc3n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G15 compound treatment 825159.0 -90100.0 -0.49 955326.0 63500.0 0.36 -0.0949 -0.1559 3626747 CBKinase1_016373 O=C(CSc1ncnc2sc3CCCc3c12)N4CCOCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G16 compound treatment 1287068.0 372000.0 2.03 917409.0 25600.0 0.14 1.5372 0.7555 3626748 CBKinase1_016374 CCOc1ccc(NC(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G17 compound treatment 1611254.0 696000.0 3.8 930592.0 38800.0 0.22 2.8412 0.7465 3626749 CBKinase1_016375 Nc1nnc(SCC(=O)c2ccc(Cl)cc2Cl)[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G18 compound treatment 881848.0 -33500.0 -0.18 853889.0 -37900.0 -0.21 -0.2803 -0.9969 3626750 CBKinase1_016376 CC(C)(C)C(=O)CSc1nnc(c2ccncc2)n1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G19 mock treatment 798595.0 -117000.0 -0.64 813634.0 -78200.0 -0.44 -0.7621 -0.9838 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G20 mock treatment 762070.0 -153000.0 -0.84 763132.0 -129000.0 -0.73 -1.1044 -0.9975 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G21 compound treatment 809476.0 -106000.0 -0.58 788247.0 -104000.0 -0.58 -0.8213 -1.0 3626751 CBKinase1_016377 O=C(CCN1C(=O)c2ccccc2S1(=O)=O)NCc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G22 compound treatment 780958.0 -134000.0 -0.73 764201.0 -128000.0 -0.72 -1.0272 -1.0 3626752 CBKinase1_016378 OC1CC(N(C1)S(=O)(=O)c2ccc(Cl)cc2)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G23 compound treatment 774770.0 -141000.0 -0.77 903407.0 11600.0 0.07 -0.4963 -0.6446 3626753 CBKinase1_016379 O=C(CSc1ncnc2scc(c3ccccc3)c12)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 G24 compound treatment 680097.0 -235000.0 -1.28 735445.0 -156000.0 -0.88 -1.5312 -0.9831 3626754 CBKinase1_016380 CCc1cccc(C)c1NC(=O)CSc2nnc(c3ccc(OC)cc3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H01 compound treatment 801792.0 -114000.0 -0.62 664250.0 -228000.0 -1.28 -1.3452 -0.9443 3626755 CBKinase1_016381 COc1ccc(cc1)c2nnc(SCC(=O)Nc3cc(Cl)c(Cl)cc3Cl)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H02 compound treatment 771657.0 -144000.0 -0.78 750631.0 -141000.0 -0.8 -1.1172 -1.0 3626756 CBKinase1_016382 COC(=O)c1cc(NC(=O)CSc2nc(C)nc3sc4CCCc4c23)cc(c1)C(=O)OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H03 mock treatment 836617.0 -78700.0 -0.43 694915.0 -197000.0 -1.11 -1.0885 -0.9147 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H04 mock treatment 811001.0 -104000.0 -0.57 628927.0 -263000.0 -1.48 -1.4504 -0.9137 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H05 compound treatment 865198.0 -50100.0 -0.27 753244.0 -139000.0 -0.78 -0.7457 -0.9011 3211381 CBKinase1_016383 Cc1ccccc1C(=O)Nc2c(C)nc(O)nc2O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H06 compound treatment 753981.0 -161000.0 -0.88 762857.0 -129000.0 -0.73 -1.1367 -0.9954 3626757 CBKinase1_016384 Cc1c(CO)c2ccccc2n1Cc3ccccc3C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H07 compound treatment 1362222.0 447000.0 2.44 1737631.0 846000.0 4.77 5.0963 0.9516 3626758 CBKinase1_016385 COc1ccc(cc1)C(=O)Nc2sc3CCCc3c2C(=O)Nc4cccc(OC)c4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H08 compound treatment 900602.0 -14700.0 -0.08 909451.0 17600.0 0.1 0.0135 0.1059 3118397 CBKinase1_016386 O=C(CCN1C(=O)c2ccccc2S1(=O)=O)Nc3ccc4CCc5cccc3c54 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H09 compound treatment 909238.0 -6070.0 -0.03 795510.0 -96300.0 -0.54 -0.4072 -0.7489 3626759 CBKinase1_016387 Nc1nnc(SCC(=O)c2ccc3ccccc3c2)s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H10 compound treatment 934991.0 19700.0 0.11 923228.0 31400.0 0.18 0.2012 0.9714 1632740 CBKinase1_016388 COc1ccc(OC)c(c1)S(=O)(=O)NC2CCN(Cc3ccccc3)CC2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H11 compound treatment 944922.0 29600.0 0.16 925310.0 33500.0 0.19 0.2478 0.997 3626760 CBKinase1_016389 Nc1nnc(SCC(=O)NC2CCCCCC2)s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H12 compound treatment 981125.0 65800.0 0.36 963876.0 72100.0 0.41 0.5413 0.9981 1985881 CBKinase1_016390 OC(=O)CCc1ccc(c2cccs2)n1Cc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H13 compound treatment 983415.0 68100.0 0.37 941530.0 49700.0 0.28 0.4611 0.9903 3626761 CBKinase1_016391 CS(=O)(=O)N(CC(=O)NC1CC1)c2ccc(Cl)c(c2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H14 compound treatment 940708.0 25400.0 0.14 967447.0 75600.0 0.43 0.3995 0.8912 3626762 CBKinase1_016392 CCc1ccccc1NC(=O)CSc2ncnc3sc(C)c(C)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H15 compound treatment 971804.0 56500.0 0.31 966830.0 75000.0 0.42 0.5171 0.988 3626763 CBKinase1_016393 CC1CCc2c(C1)sc3ncnc(SCCO)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H16 compound treatment 912212.0 -3090.0 -0.02 941530.0 49700.0 0.28 0.1862 0.6633 3626764 CBKinase1_016394 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)Nc2cccc(c2)C(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H17 compound treatment 995151.0 79800.0 0.44 981602.0 89800.0 0.51 0.6661 0.9972 3626765 CBKinase1_016395 CC(N1C(=O)C2C(C3C=CC2C4CC43)C1=O)C(=O)Nc5cccc(c5)C(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H18 compound treatment 915306.0 1.47 0.0 935564.0 43700.0 0.25 0.1744 0.7071 3626766 CBKinase1_016396 COc1ccc(NC(=O)CSc2nnc(c3ccc(Cl)cc3)n2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H19 mock treatment 913424.0 -1880.0 -0.01 918551.0 26700.0 0.15 0.0993 0.6574 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H20 mock treatment 884052.0 -31300.0 -0.17 889116.0 -2700.0 -0.02 -0.1314 -0.7671 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H21 compound treatment 843965.0 -71300.0 -0.39 881157.0 -10700.0 -0.06 -0.3179 -0.8066 1476821 CBKinase1_016397 OC1(CC(=O)c2ccc(Br)s2)C(=O)N(Cc3cccc4ccccc34)c5ccccc51 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H22 compound treatment 961739.0 46400.0 0.25 961113.0 69300.0 0.39 0.4555 0.9781 1638814 CBKinase1_016398 Cc1sc2nc3c4ccccc4c(NCc5ccccn5)nn3c(=O)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H23 compound treatment 857605.0 -57700.0 -0.32 833892.0 -57900.0 -0.33 -0.4536 -0.9998 3626767 CBKinase1_016399 Cc1cc(C(F)F)n2nc(nc2n1)C(=O)Nc3ccc(cc3)S(=O)(=O)N4CCCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 H24 compound treatment 787677.0 -128000.0 -0.7 803307.0 -88500.0 -0.5 -0.8455 -0.9866 3626768 CBKinase1_016400 COc1ccc(cc1OC)S(=O)(=O)N(C)CC(=O)Nc2cccc(Cl)c2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I01 compound treatment 703732.0 -212000.0 -1.16 753819.0 -138000.0 -0.78 -1.3668 -0.9815 3626769 CBKinase1_016401 COc1ccccc1N2CCN(CC2)C(=O)CN(c3ccc4OCCOc4c3)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I02 compound treatment 919403.0 4100.0 0.02 947283.0 55500.0 0.31 0.2369 0.7558 3626770 CBKinase1_016402 NC(=O)C1(CCN(CC1)C(=O)CSc2nc3ccccc3[nH]2)N4CCCCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I03 compound treatment 967439.0 52100.0 0.28 972154.0 80300.0 0.45 0.5215 0.975 3626771 CBKinase1_016403 C(COc1ccccc1)Cc2nc(no2)c3ccccn3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I04 compound treatment 929317.0 14000.0 0.08 928720.0 36900.0 0.21 0.2012 0.9077 1985880 CBKinase1_016404 CCn1c(SCc2nc(O)c3ccccc3n2)nc4ccccc4c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I05 mock treatment 991709.0 76400.0 0.42 1038578.0 147000.0 0.83 0.8799 0.9498 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I06 mock treatment 1024399.0 109000.0 0.6 1002127.0 110000.0 0.62 0.8608 0.9998 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I07 compound treatment 972618.0 57300.0 0.31 987040.0 95200.0 0.54 0.6008 0.967 3626772 CBKinase1_016405 O=c1n(c(SCc2cccc3nsnc23)nc4ccccc14)c5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I08 compound treatment 1014337.0 99000.0 0.54 981524.0 89700.0 0.51 0.7399 0.9994 3626773 CBKinase1_016406 Clc1ccc(cc1)c2nn(CCC(=O)Nc3ccc(Br)cc3)c(=O)c4ccccc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I09 compound treatment 1068745.0 153000.0 0.84 1050989.0 159000.0 0.9 1.2267 0.9994 3626774 CBKinase1_016407 CS(=O)(=O)N(CC(=O)Nc1ccc(F)c(Cl)c1)c2ccc3OCCOc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I10 compound treatment 1078519.0 163000.0 0.89 1136692.0 245000.0 1.38 1.6061 0.9776 3626775 CBKinase1_016408 Cc1n[nH]c(SCCCSc2nc(C)n[nH]2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I11 compound treatment 1105274.0 190000.0 1.04 1049122.0 157000.0 0.89 1.3603 0.997 3626776 CBKinase1_016409 CC(O)c1nc2ccccc2n1CCOc3cccc(C)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I12 compound treatment 1084419.0 169000.0 0.92 1056819.0 165000.0 0.93 1.3105 1.0 3626777 CBKinase1_016410 COc1ccc(cc1OC)c2csc3ncn(CC(=O)Nc4sc5CCCc5c4C#N)c(=O)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I13 compound treatment 1088978.0 174000.0 0.95 1006293.0 114000.0 0.65 1.1267 0.9824 3626778 CBKinase1_016411 CCc1ccc(OCC(=O)Nc2sc3CCCCc3c2C(=O)N)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I14 compound treatment 896785.0 -18500.0 -0.1 928634.0 36800.0 0.21 0.0753 0.326 3626779 CBKinase1_016412 COc1ccc(NC(=O)CCn2nc(c3ccccc3)c4ccccc4c2=O)cc1C(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I15 compound treatment 1118541.0 203000.0 1.11 992411.0 101000.0 0.57 1.1855 0.9514 3626780 CBKinase1_016413 COC(=O)c1cccc(c1)n2c(CCC(=O)O)ccc2c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I16 compound treatment 1088805.0 174000.0 0.95 1019462.0 128000.0 0.72 1.1785 0.9908 3626781 CBKinase1_016414 CC1CCc2c(C1)sc3ncnc(SCC(=O)NCc4ccco4)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I17 compound treatment 1080584.0 165000.0 0.9 1587020.0 695000.0 3.92 3.4088 0.8478 3626782 CBKinase1_016415 COc1ccc(C)cc1N(CC(=O)Nc2ccccc2c3ccccc3)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I18 compound treatment 1002167.0 86900.0 0.47 1052533.0 161000.0 0.91 0.9759 0.9544 3626783 CBKinase1_016416 COc1cc(ccc1OCC(O)Cn2nc(C)c(C(=O)C)c2C)C(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I19 compound treatment 1026992.0 112000.0 0.61 946440.0 54600.0 0.31 0.6489 0.9499 3626784 CBKinase1_016417 CN(CC(=O)Nc1ccc(C)cc1C)S(=O)(=O)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I20 compound treatment 989647.0 74300.0 0.41 922078.0 30300.0 0.17 0.4076 0.9258 1415079 CBKinase1_016418 Cc1ccc(cc1)n2c(SCC(=O)Nc3c(C)cccc3C)nc4ccccc4c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I21 mock treatment 1034488.0 119000.0 0.65 923940.0 32100.0 0.18 0.5881 0.8708 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I22 mock treatment 1059484.0 144000.0 0.79 935089.0 43300.0 0.24 0.7291 0.8847 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I23 compound treatment 1237814.0 323000.0 1.76 903115.0 11300.0 0.06 1.2901 0.7322 3626785 CBKinase1_016419 COc1ccc(NC(=O)CN2C(=O)c3cccc4cccc2c34)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 I24 compound treatment 878030.0 -37300.0 -0.2 874160.0 -17700.0 -0.1 -0.2143 -0.9458 3626786 CBKinase1_016420 COC(=O)CSc1nc(nc(n1)N(C)C)N(C)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J01 compound treatment 839035.0 -76300.0 -0.42 616318.0 -275000.0 -1.55 -1.3924 -0.8661 1669032 CBKinase1_016421 O=C(COc1ccc2oc3CCCCc3c2c1)Nc4cccnc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J02 compound treatment 747564.0 -168000.0 -0.92 629954.0 -262000.0 -1.48 -1.6912 -0.9737 3626787 CBKinase1_016422 COc1ccc(NC(=O)c2c(NCc3cccnc3)sc4CCCc24)c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J03 compound treatment 973643.0 58300.0 0.32 814561.0 -77300.0 -0.44 -0.0827 -0.1533 3626788 CBKinase1_016423 CN(CC(=O)Nc1ccc(cc1)C(=O)N)S(=O)(=O)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J04 compound treatment 944298.0 29000.0 0.16 743034.0 -149000.0 -0.84 -0.481 -0.5637 3626789 CBKinase1_016424 COc1ccc(NC(=O)CNS(=O)(=O)c2ccc(C)cc2)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J05 mock treatment 1003693.0 88400.0 0.48 809323.0 -82500.0 -0.46 0.0124 0.0186 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J06 mock treatment 1012158.0 96900.0 0.53 890164.0 -1650.0 -0.01 0.3673 0.6946 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J07 compound treatment 991560.0 76300.0 0.42 813857.0 -78000.0 -0.44 -0.0163 -0.027 3626790 CBKinase1_016425 [O-][N+](=O)c1ccc(NCc2cccnc2)c(c1)C(=O)Nc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J08 compound treatment 882490.0 -32800.0 -0.18 892521.0 707.0 0.0 -0.1239 -0.6912 3626791 CBKinase1_016426 O=S(=O)(CCSc1nc2ccccc2o1)c3nc4ccccc4s3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J09 compound treatment 1013560.0 98300.0 0.54 918557.0 26700.0 0.15 0.4859 0.872 3626792 CBKinase1_016427 CCN(CC)C(=O)CSc1nc(O)c2c(C)c(C)sc2n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J10 compound treatment 1091992.0 177000.0 0.96 1018884.0 127000.0 0.72 1.1885 0.9893 3626793 CBKinase1_016428 COc1ccc(CC(=O)Nc2ccc(cc2)C(=O)Nc3ccccc3C(=O)O)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J11 compound treatment 1080348.0 165000.0 0.9 995266.0 103000.0 0.58 1.0495 0.9778 3626794 CBKinase1_016429 Cc1nnc(SCC(=O)Nc2ccc(Br)cc2)[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J12 compound treatment 1125296.0 210000.0 1.15 964755.0 72900.0 0.41 1.1014 0.9043 3626795 CBKinase1_016430 CN(CC(=O)Nc1cccc(c1)C(=O)C)S(=O)(=O)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J13 compound treatment 1094227.0 179000.0 0.98 1058482.0 167000.0 0.94 1.355 0.9998 1803919 CBKinase1_016431 CC(Sc1nc2ccccc2[nH]1)C(=O)Nc3ccc(cc3)S(=O)(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J14 compound treatment 1057749.0 142000.0 0.78 1056800.0 165000.0 0.93 1.2075 0.996 3626796 CBKinase1_016432 CC(C)c1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc(F)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J15 compound treatment 1096072.0 181000.0 0.99 1103319.0 212000.0 1.19 1.5408 0.9956 3626797 CBKinase1_016433 CN(CC(=O)N1CCC(CC1)C(=O)N)S(=O)(=O)c2c(C)cc(C)cc2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J16 compound treatment 1081464.0 166000.0 0.91 974742.0 82900.0 0.47 0.972 0.9524 3626798 CBKinase1_016434 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)Nc2cc(Cl)cc(Cl)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J17 compound treatment 1074747.0 159000.0 0.87 1077992.0 186000.0 1.05 1.3575 0.9957 3626799 CBKinase1_016435 CC(Sc1nnc(C)[nH]1)C(=O)Nc2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J18 compound treatment 1059450.0 144000.0 0.79 1020170.0 128000.0 0.72 1.068 0.9991 3626800 CBKinase1_016436 CC(=O)Nc1ccc(NC(=O)CN(c2cccc(c2)C(F)(F)F)S(=O)(=O)C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J19 compound treatment 1015911.0 101000.0 0.55 984416.0 92600.0 0.52 0.7575 0.9997 3626801 CBKinase1_016437 COc1ccc(cc1)c2nnc(SCC(=O)N)n2c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J20 compound treatment 931729.0 16400.0 0.09 993276.0 101000.0 0.57 0.4678 0.8081 3626802 CBKinase1_016438 Cc1ccc(C)c(NC(=O)CN(c2cccc(F)c2)S(=O)(=O)C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J21 mock treatment 1010978.0 95700.0 0.52 906651.0 14800.0 0.08 0.4285 0.81 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J22 mock treatment 835209.0 -80100.0 -0.44 878107.0 -13700.0 -0.08 -0.3638 -0.8193 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J23 compound treatment 900240.0 -15100.0 -0.08 844523.0 -47300.0 -0.27 -0.2466 -0.8842 3626803 CBKinase1_016439 Cc1cc(ccc1Cl)S(=O)(=O)NCC(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 J24 compound treatment 512639.0 -403000.0 -2.2 771073.0 -121000.0 -0.68 -2.0357 -0.8846 3626804 CBKinase1_016440 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)Nc2ccccc2C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K01 compound treatment 900350.0 -15000.0 -0.08 888039.0 -3780.0 -0.02 -0.0728 -0.8626 3626805 CBKinase1_016441 CC(C)c1ccc(NC(=O)CSc2nnc([nH]2)c3ccccc3Cl)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K02 compound treatment 779964.0 -135000.0 -0.74 741894.0 -150000.0 -0.85 -1.12 -0.9978 3626806 CBKinase1_016442 COc1ccc(cc1OC)S(=O)(=O)N(C)CC(=O)Nc2cccc(F)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K03 compound treatment 968783.0 53500.0 0.29 777355.0 -114000.0 -0.65 -0.2497 -0.3527 3626807 CBKinase1_016443 CCOc1ccccc1NC(=O)COc2cc(N3CCOCC3)c4ccccc4c2Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K04 compound treatment 908045.0 -7260.0 -0.04 856007.0 -35800.0 -0.2 -0.1707 -0.8301 3626808 CBKinase1_016444 Cc1cc(C)c(C)c(Oc2coc3cc(OCC(=O)Nc4ccccc4Cl)ccc3c2=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K05 compound treatment 789336.0 -126000.0 -0.69 899031.0 7220.0 0.04 -0.4575 -0.6641 3626809 CBKinase1_016445 COc1ccc(OC)c(NC(=O)CSc2nnc(c3ccc(F)cc3)n2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K06 compound treatment 854945.0 -60400.0 -0.33 904560.0 12700.0 0.07 -0.1822 -0.5403 3626810 CBKinase1_016446 NC(=O)CSc1nnc(SCc2cccc3ccccc23)s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K07 mock treatment 858291.0 -57000.0 -0.31 935745.0 43900.0 0.25 -0.045 -0.1132 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K08 mock treatment 979606.0 64300.0 0.35 957469.0 65700.0 0.37 0.5099 0.9997 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K09 compound treatment 837333.0 -78000.0 -0.43 889713.0 -2100.0 -0.01 -0.3094 -0.7265 3626811 CBKinase1_016447 Cn1cc(C(c2ccc(o2)[N+](=O)[O-])c3cn(C)c4ccccc34)c5ccccc15 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K10 compound treatment 754549.0 -161000.0 -0.88 998995.0 107000.0 0.6 -0.1934 -0.1815 3626812 CBKinase1_016448 CCC(C)Cn1c(CCCO)nc2ccccc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K11 compound treatment 928149.0 12800.0 0.07 1013080.0 121000.0 0.68 0.5329 0.7756 3626813 CBKinase1_016449 Cc1ccc(cc1)C2CC(=O)c3cnc(NCCN4CCOCC4)nc3C2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K12 compound treatment 863328.0 -52000.0 -0.28 1001192.0 109000.0 0.62 0.2353 0.3467 3118252 CBKinase1_016450 Cc1cc(C)nc(SCc2cc(ccc2C)c3nn(C)c(=O)c4ccccc34)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K13 compound treatment 872153.0 -43200.0 -0.24 892439.0 625.0 0.0 -0.1641 -0.6965 3626814 CBKinase1_016451 Cc1cc(C)cc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccccc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K14 compound treatment 1195714.0 280000.0 1.53 1033792.0 142000.0 0.8 1.6484 0.9542 3626815 CBKinase1_016452 Cc1cc(C)c(NC(=O)CSc2nnc(c3ccccc3Cl)n2C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K15 mock treatment 848665.0 -66600.0 -0.36 955151.0 63300.0 0.36 -0.0048 -0.0095 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K16 mock treatment 924592.0 9290.0 0.05 988017.0 96200.0 0.54 0.4193 0.7699 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K17 compound treatment 1011245.0 95900.0 0.52 771987.0 -120000.0 -0.68 -0.1072 -0.1254 1232350 CBKinase1_016453 Brc1ccccc1NC(=O)CN2C(=O)c3ccccc3S2(=O)=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K18 compound treatment 889950.0 -25400.0 -0.14 909943.0 18100.0 0.1 -0.0256 -0.149 3626816 CBKinase1_016454 OC(=O)CSc1ccc(Br)c2cccc(C(=O)O)c12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K19 compound treatment 729020.0 -186000.0 -1.02 714273.0 -178000.0 -1.0 -1.4267 -1.0 1984169 CBKinase1_016455 COc1ccccc1OCC(=O)Nc2cc(ccc2C)c3nc4ccccc4[nH]3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K20 compound treatment 946387.0 31100.0 0.17 878294.0 -13500.0 -0.08 0.0661 0.3554 2068720 CBKinase1_016456 Clc1ccc(Cn2ncc3c(NCc4cccnc4)ncnc23)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K21 compound treatment 847057.0 -68200.0 -0.37 876410.0 -15400.0 -0.09 -0.3249 -0.8491 3626817 CBKinase1_016457 Fc1ccc(cc1)n2c(SCC(=O)Nc3ccccc3Cl)nnc2c4ccc(Cl)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K22 compound treatment 799033.0 -116000.0 -0.63 770678.0 -121000.0 -0.68 -0.9317 -0.9993 3626818 CBKinase1_016458 COc1cc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccc(C)cc4)cc(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K23 mock treatment 941521.0 26200.0 0.14 898284.0 6470.0 0.04 0.127 0.8598 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 K24 mock treatment 735773.0 -180000.0 -0.98 745099.0 -147000.0 -0.83 -1.2778 -0.9964 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L01 compound treatment 975106.0 59800.0 0.33 696769.0 -195000.0 -1.1 -0.5465 -0.4765 3626819 CBKinase1_016459 COc1ccc(cc1CNS(=O)(=O)c2ccc(Cl)cc2)c3nn(C)c(=O)c4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L02 compound treatment 873386.0 -41900.0 -0.23 815157.0 -76700.0 -0.43 -0.4673 -0.9558 3626820 CBKinase1_016460 O=C(Oc1ccc(cc1)N(Cc2ccco2)C3=NS(=O)(=O)c4ccccc34)c5ccco5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L03 compound treatment 918785.0 3480.0 0.02 973948.0 82100.0 0.46 0.3408 0.7355 1686477 CBKinase1_016461 COc1ccc(cc1OC)c2cc(C(=O)OCc3ccco3)c4ccccc4n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L04 compound treatment 882434.0 -32900.0 -0.18 930982.0 39200.0 0.22 0.0292 0.1027 3626821 CBKinase1_016462 CCn1c(SCC(=O)Nc2ccccc2OC)nnc1c3ccncc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L05 compound treatment 1009182.0 93900.0 0.51 934270.0 42500.0 0.24 0.5316 0.9399 3626822 CBKinase1_016463 FC(F)c1cc(nc2c(cnn12)C(=O)NCc3cccnc3)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L06 compound treatment 920204.0 4900.0 0.03 980379.0 88600.0 0.5 0.3719 0.7439 1717572 CBKinase1_016464 CCOc1ccccc1NC(=O)Cn2cnc3scc(c4ccc(Cl)cc4)c3c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L07 mock treatment 1054571.0 139000.0 0.76 919756.0 27900.0 0.16 0.649 0.8358 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L08 mock treatment 1001709.0 86400.0 0.47 1030344.0 139000.0 0.78 0.8857 0.9709 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L09 compound treatment 1001262.0 86000.0 0.47 935855.0 44000.0 0.25 0.5074 0.9557 3626823 CBKinase1_016465 COC(=O)c1ccc(NC(=O)CCn2nc(c3ccc(Cl)cc3)c4ccccc4c2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L10 compound treatment 1043643.0 128000.0 0.7 1068784.0 177000.0 1.0 1.2008 0.9851 3626824 CBKinase1_016466 CC(=O)Nc1ccc(NC(=O)CN(c2ccc(F)cc2)S(=O)(=O)C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L11 compound treatment 1103491.0 188000.0 1.03 1042405.0 151000.0 0.85 1.3267 0.9955 3626825 CBKinase1_016467 CC(C)c1cc(Br)ccc1NC(=O)CSc2nnc(c3cccc(C)c3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L12 compound treatment 949089.0 33800.0 0.18 964990.0 73200.0 0.41 0.4221 0.9342 3626826 CBKinase1_016468 Cc1ccccc1OCC(=O)Nc2cccc(Oc3ccc4C(=O)NC(=O)c4c3)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L13 compound treatment 1107390.0 192000.0 1.05 1070427.0 179000.0 1.01 1.4534 0.9998 3626827 CBKinase1_016469 COc1ccc(cc1)c2nnc(SCC(=O)Nc3ccc4cn[nH]c4c3)n2c5ccc(Cl)cc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L14 compound treatment 983309.0 68000.0 0.37 969263.0 77400.0 0.44 0.5712 0.9968 3626828 CBKinase1_016470 COc1ccc(cc1NC(=O)CN(c2ccccc2F)S(=O)(=O)C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L15 mock treatment 1010097.0 94800.0 0.52 947928.0 56100.0 0.32 0.5896 0.9721 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L16 mock treatment 1047897.0 133000.0 0.72 1044954.0 153000.0 0.86 1.1222 0.9962 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L17 compound treatment 996873.0 81600.0 0.45 1007824.0 116000.0 0.65 0.7773 0.9825 3626829 CBKinase1_016471 O=c1oc2ccccc2n1CCn3c4ccccc4c5nc6ccccc6nc35 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L18 compound treatment 906465.0 -8840.0 -0.05 957161.0 65300.0 0.37 0.2263 0.6093 3626830 CBKinase1_016472 CN(CC(=O)Nc1ccc(Cl)cc1Cl)S(=O)(=O)c2c(C)cc(C)cc2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L19 compound treatment 771842.0 -143000.0 -0.78 860677.0 -31100.0 -0.18 -0.6779 -0.8446 3626831 CBKinase1_016473 COc1ccc(OC)c(NC(=O)CC2Nc3cc(C)c(C)cc3NC2=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L20 compound treatment 1068624.0 153000.0 0.84 953752.0 61900.0 0.35 0.8387 0.9248 3626832 CBKinase1_016474 OCc1ccc(OCC(=O)Nc2ccc(F)cc2)c(Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L21 compound treatment 945275.0 30000.0 0.16 938651.0 46800.0 0.26 0.3024 0.9735 3626833 CBKinase1_016475 COc1ccc(cc1)c2nnc(SCC(=O)Nc3ccc(Br)cc3C(C)C)o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L22 compound treatment 935954.0 20600.0 0.11 926710.0 34900.0 0.2 0.2188 0.9651 3626834 CBKinase1_016476 Cc1sc2ncnc(SCC(=O)Nc3ccccc3Cl)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L23 mock treatment 943352.0 28000.0 0.15 857238.0 -34600.0 -0.19 -0.0295 -0.1191 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 L24 mock treatment 933744.0 18400.0 0.1 899676.0 7860.0 0.04 0.1025 0.9321 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M01 compound treatment 960886.0 45600.0 0.25 926029.0 34200.0 0.19 0.3123 0.9921 3626835 CBKinase1_016477 COc1ccc(NC(=O)CSc2nc3sc4CCCc4c3c(=O)n2c5ccccc5)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M02 compound treatment 822174.0 -93100.0 -0.51 856851.0 -35000.0 -0.2 -0.4989 -0.9149 3118997 CBKinase1_016478 Clc1ccc(cc1)c2nn(CCC(=O)NCC3CCCO3)c(=O)c4ccccc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M03 compound treatment 897097.0 -18200.0 -0.1 967713.0 75900.0 0.43 0.2322 0.5287 3626836 CBKinase1_016479 COc1ccc(cc1CSc2nnc(c3cccc(Br)c3)n2c4ccccc4)C(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M04 compound treatment 844227.0 -71100.0 -0.39 937333.0 45500.0 0.26 -0.093 -0.1999 3626837 CBKinase1_016480 CCOc1ccc2[nH]c(SCC(=O)Nc3ccc(cc3)[N+](=O)[O-])nc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M05 compound treatment 749521.0 -166000.0 -0.91 850002.0 -41800.0 -0.24 -0.8066 -0.8625 3626838 CBKinase1_016481 O=C(CSc1nnnn1Cc2ccccc2)n3c4CCCCc4c5CCCCc53 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M06 compound treatment 939835.0 24500.0 0.13 947714.0 55900.0 0.32 0.3175 0.9274 3626839 CBKinase1_016482 OC(COc1ccccc1F)Cn2cnc3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M07 compound treatment 912321.0 -2980.0 -0.02 966531.0 74700.0 0.42 0.2863 0.6792 3626840 CBKinase1_016483 CS(=O)(=O)N(CC(=O)Nc1ccc(Oc2ccccc2)cc1)c3ccc4OCCOc4c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M08 compound treatment 916998.0 1690.0 0.01 1011056.0 119000.0 0.67 0.4818 0.7168 3626841 CBKinase1_016484 CSc1cccc(NC(=O)CSc2nnc(o2)c3ccc(Br)cc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M09 mock treatment 940703.0 25400.0 0.14 975954.0 84100.0 0.47 0.4334 0.8771 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M10 mock treatment 933516.0 18200.0 0.1 1020257.0 128000.0 0.72 0.5822 0.7967 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M11 compound treatment 743993.0 -171000.0 -0.94 950534.0 58700.0 0.33 -0.4273 -0.4307 3626842 CBKinase1_016485 CSc1cccc(NC(=O)CSc2nnc(c3cccc(C)c3)n2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M12 compound treatment 920068.0 4760.0 0.03 990759.0 98900.0 0.56 0.4127 0.7393 3626843 CBKinase1_016486 NS(=O)(=O)c1ccc(NC(=O)CN2CCN(Cc3ccccc3)CC2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M13 mock treatment 946221.0 30900.0 0.17 968731.0 76900.0 0.43 0.4259 0.9155 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M14 mock treatment 946700.0 31400.0 0.17 898140.0 6330.0 0.04 0.1464 0.8363 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M15 compound treatment 929949.0 14600.0 0.08 957318.0 65500.0 0.37 0.3176 0.8407 3626844 CBKinase1_016487 Cc1nnc(SCC(=O)Nc2ccc(Cl)cc2Cl)n1c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M16 compound treatment 1148122.0 233000.0 1.27 1043742.0 152000.0 0.86 1.5043 0.9815 3626845 CBKinase1_016488 COc1ccc(cc1)c2cc(c(C#N)c(SCC(=O)Nc3ccccc3F)n2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M17 compound treatment 861563.0 -53700.0 -0.29 978992.0 87200.0 0.49 0.14 0.2446 1497879 CBKinase1_016489 Cc1ccc(NC(=O)c2ccc(OC(=O)CN3C(=O)c4ccccc4C3=O)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M18 compound treatment 899865.0 -15400.0 -0.08 953734.0 61900.0 0.35 0.1872 0.5213 3626846 CBKinase1_016490 Fc1cccc(NC(=O)CSc2nc3ccccc3c(=O)n2c4ccc(Br)cc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M19 compound treatment 984564.0 69300.0 0.38 1019704.0 128000.0 0.72 0.7771 0.9547 3626847 CBKinase1_016491 CC(C)c1ccc(NC(=O)CNS(=O)(=O)c2ccc(Br)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M20 compound treatment 975621.0 60300.0 0.33 878489.0 -13300.0 -0.08 0.1797 0.5322 1986089 CBKinase1_016492 Cc1cccc(Nc2nc(N)nc(CSc3nccn3C)n2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M21 compound treatment 1008043.0 92700.0 0.51 982052.0 90200.0 0.51 0.7177 1.0 3626848 CBKinase1_016493 [O-][N+](=O)c1cccc(NC(=O)CNS(=O)(=O)c2ccc(Cl)cc2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M22 compound treatment 940727.0 25400.0 0.14 867810.0 -24000.0 -0.14 0.0025 0.0128 3626849 CBKinase1_016494 Ic1ccc(NC(=O)Cn2cnc3ccccc3c2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M23 compound treatment 902552.0 -12800.0 -0.07 870279.0 -21500.0 -0.12 -0.1351 -0.9652 3626850 CBKinase1_016495 CNC(=O)CN(c1cccc(F)c1)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 M24 compound treatment 961134.0 45800.0 0.25 769557.0 -122000.0 -0.69 -0.3103 -0.4233 3626851 CBKinase1_016496 [O-][N+](=O)CC(=O)CCN1C(=O)c2ccccc2C1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N01 compound treatment 986132.0 70800.0 0.39 1086473.0 195000.0 1.1 1.0492 0.9019 3626852 CBKinase1_016497 CCOC(=O)c1c(NC(=O)c2nc3nc(C)cc(C(F)F)n3n2)sc4CCCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N02 compound treatment 913489.0 -1820.0 -0.01 899831.0 8020.0 0.05 0.0249 0.5392 1311212 CBKinase1_016498 CCOc1ccccc1C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ccccn3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N03 compound treatment 852323.0 -63000.0 -0.34 932705.0 40900.0 0.23 -0.0802 -0.1937 3626853 CBKinase1_016499 COc1ccc(cc1)c2nnc(SCC(=O)Nc3ccc(Br)c(C)c3C)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N04 compound treatment 902712.0 -12600.0 -0.07 918439.0 26600.0 0.15 0.0575 0.3484 3626854 CBKinase1_016500 CC(=O)Nc1ccc(NC(=O)CN(c2ccc(C)c(Cl)c2)S(=O)(=O)C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N05 compound treatment 899057.0 -16200.0 -0.09 1023489.0 132000.0 0.74 0.4621 0.6182 3626855 CBKinase1_016501 Ic1ccc(NC(=O)c2ccco2)c(c1)C(=O)NCc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N06 compound treatment 898969.0 -16300.0 -0.09 1009619.0 118000.0 0.66 0.4065 0.6067 3626856 CBKinase1_016502 Cn1c(SCC(=O)Nc2ccc(Cl)cc2Cl)nnc1c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N07 compound treatment 948594.0 33300.0 0.18 1032541.0 141000.0 0.79 0.6894 0.8472 3626857 CBKinase1_016503 CC(NS(=O)(=O)c1c(C)ccc2nsnc12)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N08 compound treatment 1086980.0 172000.0 0.94 994627.0 103000.0 0.58 1.0725 0.9733 3626858 CBKinase1_016504 Cc1ccc(OCC(=O)Nc2ccc(Br)cc2C(=O)O)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N09 mock treatment 1027422.0 112000.0 0.61 972356.0 80500.0 0.45 0.7538 0.9892 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N10 mock treatment 985553.0 70200.0 0.38 897045.0 5230.0 0.03 0.292 0.7592 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N11 compound treatment 919832.0 4530.0 0.02 1048722.0 157000.0 0.88 0.6428 0.7266 2068624 CBKinase1_016505 CCN(CC)C(=O)CSc1nc(N)cc(O)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N12 compound treatment 1084744.0 169000.0 0.93 1098344.0 207000.0 1.16 1.4772 0.9935 3626859 CBKinase1_016506 Fc1ccc(cc1)n2c(SCC(=O)N3CCOCC3)nnc2c4ccc(Cl)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N13 mock treatment 984780.0 69500.0 0.38 937071.0 45300.0 0.26 0.4486 0.9814 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N14 mock treatment 1036406.0 121000.0 0.66 1025644.0 134000.0 0.75 1.0009 0.9978 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N15 compound treatment 1022522.0 107000.0 0.59 1023370.0 132000.0 0.74 0.9382 0.9931 3626860 CBKinase1_016507 CC(Sc1ncn(n1)c2ccccc2)C(=O)Nc3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N16 compound treatment 995661.0 80400.0 0.44 985718.0 93900.0 0.53 0.6845 0.9957 3626861 CBKinase1_016508 Cc1cc(C)c(NC(=O)CN(c2cccc(c2)[N+](=O)[O-])S(=O)(=O)C)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N17 compound treatment 975091.0 59800.0 0.33 983733.0 91900.0 0.52 0.5971 0.9752 3626862 CBKinase1_016509 CCc1nnc(SCC(=O)Nc2cccc(Cl)c2)[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N18 compound treatment 968873.0 53600.0 0.29 961506.0 69700.0 0.39 0.4846 0.9894 3626863 CBKinase1_016510 CCOc1cc(CO)c(Br)cc1OCC(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N19 compound treatment 1030408.0 115000.0 0.63 997497.0 106000.0 0.6 0.8656 0.9996 3626864 CBKinase1_016511 Cc1cc(C)nc(NC2=NC(=O)CC(N2c3ccc(F)c(Cl)c3)C(=O)O)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N20 compound treatment 961848.0 46500.0 0.25 1038299.0 146000.0 0.83 0.7635 0.8838 3626865 CBKinase1_016512 CN(c1cccc(NC(=O)c2ccc(CN3CCOCC3)cc2)c1)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N21 compound treatment 952668.0 37400.0 0.2 918273.0 26500.0 0.15 0.2497 0.9881 1364983 CBKinase1_016513 CCOC(=O)c1ccc(CNS(=O)(=O)c2c(C)ccc3nsnc23)o1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N22 compound treatment 956386.0 41100.0 0.22 941954.0 50100.0 0.28 0.3584 0.9934 3626866 CBKinase1_016514 CCc1ccccc1NC(=O)CNS(=O)(=O)c2ccc(C)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N23 compound treatment 975110.0 59800.0 0.33 956151.0 64300.0 0.36 0.4873 0.9986 3626867 CBKinase1_016515 CC(=O)Nc1ccc(NC(=O)CSc2nnc3c4cc(Br)ccc4n(C)c3n2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 N24 compound treatment 1053057.0 138000.0 0.75 926334.0 34500.0 0.19 0.6694 0.8617 3626868 CBKinase1_016516 Cc1cc(C)nc(SCCS(=O)(=O)Cc2ccccc2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O01 compound treatment 964877.0 49600.0 0.27 884531.0 -7280.0 -0.04 0.1623 0.5931 3626869 CBKinase1_016517 Cc1cc2c(NC(=O)C2(O)CC(=O)c3ccccn3)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O02 compound treatment 898387.0 -16900.0 -0.09 944815.0 53000.0 0.3 0.1459 0.4667 3626870 CBKinase1_016518 Cc1ccc(c(C)c1)S(=O)(=O)NCC(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O03 compound treatment 923179.0 7870.0 0.04 963374.0 71600.0 0.4 0.3156 0.7781 3626871 CBKinase1_016519 CC(C)(C)NC(=O)CSc1nnc(c2ccccc2Cl)n1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O04 compound treatment 936828.0 21500.0 0.12 972358.0 80500.0 0.45 0.4041 0.8617 3626872 CBKinase1_016520 NC(=O)c1c(NC(=O)C2CN(C(=O)C2)c3ccc(Cl)cc3)sc4CCCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O05 compound treatment 960489.0 45200.0 0.25 945426.0 53600.0 0.3 0.3881 0.9949 3626873 CBKinase1_016521 COc1cccc(c1)c2nnc(SCC(=O)Nc3cccc(c3)[N+](=O)[O-])n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O06 compound treatment 1033522.0 118000.0 0.65 917479.0 25700.0 0.14 0.5587 0.8446 3626874 CBKinase1_016522 CCN(CC)C(=O)CSc1nc(O)c2ccccc2n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O07 compound treatment 970702.0 55400.0 0.3 926917.0 35100.0 0.2 0.3538 0.9788 3626875 CBKinase1_016523 Cc1ccc2cccc(OCC(=O)Nc3ccc(C)c(c3)[N+](=O)[O-])c2n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O08 compound treatment 987302.0 72000.0 0.39 1006756.0 115000.0 0.65 0.736 0.9713 3626876 CBKinase1_016524 COc1cc(C)c(C)cc1S(=O)(=O)n2c(C)nc3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O09 compound treatment 1007383.0 92100.0 0.5 1031875.0 140000.0 0.79 0.9137 0.9763 3120072 CBKinase1_016525 CCn1c(SCc2nc3ccccc3[nH]2)nc4cc(ccc4c1=O)C(=O)OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O10 compound treatment 1004193.0 88900.0 0.49 1014302.0 122000.0 0.69 0.8313 0.9851 3626877 CBKinase1_016526 Clc1cccc(NC(=O)CC2Nc3ccccc3NC2=O)c1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O11 mock treatment 930595.0 15300.0 0.08 932148.0 40300.0 0.23 0.2198 0.9075 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O12 mock treatment 979708.0 64400.0 0.35 953272.0 61500.0 0.35 0.4936 1.0 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O13 compound treatment 970489.0 55200.0 0.3 1045444.0 154000.0 0.87 0.8253 0.9002 3626878 CBKinase1_016527 Cc1cc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3cccs3)cc2)nc(C)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O14 compound treatment 1004220.0 88900.0 0.49 999700.0 108000.0 0.61 0.7732 0.9938 3626879 CBKinase1_016528 CC(=O)c1c(C)n(c2ccc(C)cc2)c3ccc(OC(=O)CN4C(=O)c5ccccc5C4=O)cc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O15 compound treatment 1068621.0 153000.0 0.84 1037662.0 146000.0 0.82 1.1732 1.0 3626880 CBKinase1_016529 CCn1c(SCC(=O)Nc2ccc(F)c(Cl)c2)nnc1c3ccncc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O16 compound treatment 939454.0 24100.0 0.13 962800.0 71000.0 0.4 0.3761 0.8929 3626881 CBKinase1_016530 OC1(CC(=O)c2ccc(Br)s2)C(=O)N(CCCC#N)c3ccccc31 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O17 compound treatment 947210.0 31900.0 0.17 1004920.0 113000.0 0.64 0.574 0.8685 3626882 CBKinase1_016531 COc1ccc(cc1NC(=O)CN(c2ccc(I)cc2)S(=O)(=O)C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O18 compound treatment 931241.0 15900.0 0.09 938902.0 47100.0 0.27 0.2492 0.8922 3626883 CBKinase1_016532 COc1nnc(c2ccc(N3CCOCC3)c(NC(=O)COc4ccc(C)cc4)c2)c5ccccc15 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O19 compound treatment 1015752.0 100000.0 0.55 1125111.0 233000.0 1.31 1.3176 0.9248 3626884 CBKinase1_016533 CS(=O)(=O)N(CC(=O)Nc1ccccc1c2ccccc2)c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O20 compound treatment 1001582.0 86300.0 0.47 946665.0 54900.0 0.31 0.5517 0.9791 3626885 CBKinase1_016534 NC(=O)CSc1nnc(c2ccncc2)n1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O21 compound treatment 911020.0 -4280.0 -0.02 951174.0 59400.0 0.33 0.22 0.6561 3626886 CBKinase1_016535 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2cc(Cl)ccc2C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O22 compound treatment 1006245.0 90900.0 0.5 918627.0 26800.0 0.15 0.4579 0.8824 3626887 CBKinase1_016536 CCc1nnc(SCC(=O)Nc2ccccc2C(=O)OC)[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O23 compound treatment 930995.0 15700.0 0.09 920419.0 28600.0 0.16 0.1746 0.9562 3626888 CBKinase1_016537 Cc1c(Cl)cccc1NC(=O)CCN2C(=O)c3ccccc3S2(=O)=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 O24 compound treatment 1760528.0 845000.0 4.61 919106.0 27300.0 0.15 3.3717 0.7303 3626889 CBKinase1_016538 Oc1nc(SCC(=O)Nc2ccc(Br)cc2)nc3ccccc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P01 compound treatment 868726.0 -46600.0 -0.25 901270.0 9460.0 0.05 -0.1421 -0.547 3626890 CBKinase1_016539 CCc1cccc(C)c1NC(=O)CSc2nnc(o2)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P02 compound treatment 859586.0 -55700.0 -0.3 905511.0 13700.0 0.08 -0.1605 -0.5114 3626891 CBKinase1_016540 CCn1c(SCC(=O)Nc2ccc(Cl)cc2)nnc1c3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P03 compound treatment 862663.0 -52600.0 -0.29 892437.0 623.0 0.0 -0.2007 -0.6984 1984004 CBKinase1_016541 Cc1ccc(cc1)S(=O)(=O)Nc2cccc(c2)C(=O)NC(C)(C)CO 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P04 compound treatment 907073.0 -8230.0 -0.04 953296.0 61500.0 0.35 0.2133 0.6103 3626892 CBKinase1_016542 CC1C2N(C(CC1=O)c3ccco3)C(=O)C4C(C5OC42C=C5)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P05 compound treatment 880101.0 -35200.0 -0.19 975826.0 84000.0 0.47 0.1989 0.3893 3626893 CBKinase1_016543 COc1cc(NC(=O)CCC(=O)O)ccc1NC(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P06 compound treatment 857867.0 -57400.0 -0.31 922847.0 31000.0 0.17 -0.0981 -0.2731 3626894 CBKinase1_016544 CC(NC(=O)Cn1c(nc2ccccc12)c3nonc3N)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P07 compound treatment 835980.0 -79300.0 -0.43 974464.0 82600.0 0.47 0.0232 0.0364 3626895 CBKinase1_016545 COc1ccc(cc1OC)S(=O)(=O)N(C)CC(=O)Nc2ccc3OCCOc3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P08 compound treatment 901096.0 -14200.0 -0.08 892211.0 397.0 0.0 -0.0533 -0.6864 3626896 CBKinase1_016546 COc1ccc(C)cc1N(CC(=O)Nc2ccc(I)cc2C)S(=O)(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P09 compound treatment 932357.0 17100.0 0.09 966899.0 75100.0 0.42 0.3651 0.8425 3626897 CBKinase1_016547 O=C1N(CCn2c3ccccc3c4nc5ccccc5nc24)c6ccccc6C1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P10 compound treatment 897310.0 -18000.0 -0.1 961077.0 69300.0 0.39 0.2066 0.5132 3626898 CBKinase1_016548 CCOC(=O)c1cnc2c(cccc2c1NCCCN3CCOCC3)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P11 mock treatment 900513.0 -14800.0 -0.08 975427.0 83600.0 0.47 0.2761 0.5775 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P12 mock treatment 1036385.0 121000.0 0.66 920554.0 28700.0 0.16 0.582 0.8551 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P13 compound treatment 990142.0 74800.0 0.41 957746.0 65900.0 0.37 0.5517 0.9989 3626899 CBKinase1_016549 [O-][N+](=O)c1ccccc1NC(=O)C2Cc3ccccc3CN2S(=O)(=O)c4ccc(F)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P14 compound treatment 981765.0 66500.0 0.36 937902.0 46100.0 0.26 0.4403 0.9866 1974660 CBKinase1_016550 Cc1cc(C)c(C#N)c(SCCS(=O)(=O)c2nc3ccccc3s2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P15 compound treatment 1065926.0 151000.0 0.82 1063509.0 172000.0 0.97 1.2658 0.9967 3626900 CBKinase1_016551 COc1ccc(OC)c(NC(=O)CCn2cnc3ccccc3c2=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P16 compound treatment 951470.0 36200.0 0.2 1013574.0 122000.0 0.69 0.6249 0.875 3626901 CBKinase1_016552 Cc1cccc(NC(=O)CSc2nc3c(N)ncnc3[nH]2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P17 compound treatment 1047701.0 132000.0 0.72 1023197.0 131000.0 0.74 1.0347 0.9999 1530472 CBKinase1_016553 OC1(CC(=O)c2cc3ccccc3oc2=O)C(=O)N(Cc4ccccc4)c5ccccc51 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P18 compound treatment 1012294.0 97000.0 0.53 991018.0 99200.0 0.56 0.7698 0.9996 3626902 CBKinase1_016554 COc1ccc(NC(=O)c2c(NCc3cccc(OC)c3OC)sc4CCCc24)c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P19 compound treatment 1013638.0 98300.0 0.54 1030996.0 139000.0 0.78 0.9343 0.9829 3626903 CBKinase1_016555 OC(=O)CNS(=O)(=O)c1cc(Cl)c(Cl)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P20 compound treatment 1038925.0 124000.0 0.67 996540.0 105000.0 0.59 0.8946 0.9978 3626904 CBKinase1_016556 FC(F)(F)c1cc(Br)ccc1NC(=O)CSc2nnc(c3ccncc3)n2c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P21 compound treatment 989007.0 73700.0 0.4 965726.0 73900.0 0.42 0.5791 0.9998 3626905 CBKinase1_016557 CCOC(=O)C1CCCN(Cc2nc(N)nc(Nc3ccccc3)n2)C1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P22 compound treatment 977739.0 62400.0 0.34 930353.0 38500.0 0.22 0.3946 0.9763 3626906 CBKinase1_016558 CCc1ccccc1NC(=O)CSc2nnc(c3cccc(C)c3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P23 compound treatment 960772.0 45500.0 0.25 943937.0 52100.0 0.29 0.3833 0.9965 3626907 CBKinase1_016559 Cc1nn(CC(O)COc2ccc3ccccc3c2)c(C)c1Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2375 P24 compound treatment 971258.0 56000.0 0.31 963958.0 72100.0 0.41 0.5035 0.9901 3626908 CBKinase1_016560 COc1ccc(cc1)S(=O)(=O)N(C)CC(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A01 compound treatment 873865.0 -48300.0 -0.26 999863.0 72000.0 0.41 0.1005 0.2078 3626909 CBKinase1_016561 O=C(Cn1nnc2sc3CCCCc3c2c1=O)NCc4ccco4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A02 compound treatment 927073.0 4960.0 0.03 941490.0 13600.0 0.08 0.0733 0.9023 3626910 CBKinase1_016562 Brc1cccc(NC(=O)CCn2nc(c3ccccc3)c4ccccc4c2=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A03 compound treatment 964304.0 42200.0 0.23 756857.0 -171000.0 -0.96 -0.5189 -0.5235 3626911 CBKinase1_016563 CSc1cccc(NC(=O)CSc2nnc(c3ccc(Br)cc3)n2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A04 compound treatment 874580.0 -47500.0 -0.26 1010960.0 83100.0 0.47 0.1475 0.2756 3626912 CBKinase1_016564 COc1nnc(c2ccc(N3CCOCC3)c(NS(=O)(=O)c4ccc(Cl)cc4)c2)c5ccccc15 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A05 compound treatment 960210.0 38100.0 0.21 839942.0 -88000.0 -0.5 -0.2035 -0.3785 3626913 CBKinase1_016565 COc1ccccc1NC(=O)C2=C(C)Nc3ncnn3C2c4cc(Br)c(O)c(OC)c4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A06 compound treatment 1082795.0 161000.0 0.88 1035289.0 107000.0 0.61 1.0483 0.9836 1673329 CBKinase1_016566 Cc1ccc2NC(=O)C(O)(CC(=O)c3cccnc3)c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A07 compound treatment 1010527.0 88400.0 0.48 840045.0 -87900.0 -0.5 -0.0089 -0.0128 3626914 CBKinase1_016567 Fc1ccc(cc1)N2CCN(CC2)C(=O)CSc3nnc(c4cccnc4)n3c5ccccc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A08 compound treatment 901551.0 -20600.0 -0.11 1011621.0 83700.0 0.47 0.2543 0.5242 3626915 CBKinase1_016568 CCOc1ccccc1NC(=O)CN2C(=O)C(=O)c3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A09 compound treatment 939042.0 16900.0 0.09 857431.0 -70500.0 -0.4 -0.2155 -0.5285 3626916 CBKinase1_016569 CN(CC(=O)Nc1ccccc1C(F)(F)F)S(=O)(=O)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A10 compound treatment 832390.0 -89700.0 -0.49 907664.0 -20200.0 -0.11 -0.4271 -0.8491 3626917 CBKinase1_016570 CCn1c(SCC(=O)Nc2ccc(cc2)C(=O)O)nnc1c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A11 compound treatment 983282.0 61200.0 0.33 984336.0 56400.0 0.32 0.461 0.9997 3626918 CBKinase1_016571 Cc1ccc(NC(=O)CCn2nc(c3ccccc3)c4ccccc4c2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A12 compound treatment 943751.0 21600.0 0.12 1094716.0 167000.0 0.94 0.7483 0.7897 1986055 CBKinase1_016572 Nc1nc(COc2cccc3cccnc23)nc(Nc4ccccc4)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A13 mock treatment 984002.0 61900.0 0.34 958026.0 30100.0 0.17 0.3589 0.9493 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A14 mock treatment 974239.0 52100.0 0.28 992482.0 64600.0 0.36 0.4586 0.9926 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A15 compound treatment 976100.0 54000.0 0.29 921026.0 -6880.0 -0.04 0.181 0.6088 3626919 CBKinase1_016573 CCn1c(SCC(=O)Nc2c(Cl)cc(Cl)cc2Cl)nnc1c3ccc(OC)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A16 compound treatment 942517.0 20400.0 0.11 867686.0 -60200.0 -0.34 -0.1613 -0.4514 3626920 CBKinase1_016574 Cc1ccc(cc1)c2cc(C(F)F)n3ncc(C(=O)NCCN4CCOCC4)c3n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A17 compound treatment 1037605.0 115000.0 0.63 925937.0 -1970.0 -0.01 0.438 0.6946 3626921 CBKinase1_016575 CN(CC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F)S(=O)(=O)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A18 compound treatment 918125.0 -3990.0 -0.02 905009.0 -22900.0 -0.13 -0.1067 -0.815 1297103 CBKinase1_016576 NC(=O)CN1C(=O)C(O)(CC(=O)c2ccc3OCCOc3c2)c4ccccc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A19 compound treatment 1149299.0 227000.0 1.24 1120294.0 192000.0 1.08 1.6438 0.9978 3626922 CBKinase1_016577 COC(=O)c1ccccc1NC(=O)CN(C)S(=O)(=O)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A20 compound treatment 934676.0 12600.0 0.07 905941.0 -22000.0 -0.12 -0.0391 -0.276 3626923 CBKinase1_016578 CN(CC(=O)Nc1ccc2OCCOc2c1)S(=O)(=O)c3c(C)cc(C)cc3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A21 compound treatment 1096086.0 174000.0 0.95 843754.0 -84200.0 -0.47 0.3362 0.3167 3626924 CBKinase1_016579 CCOc1ccccc1OCC(=O)Nc2cc(Cl)ccc2OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A22 compound treatment 847422.0 -74700.0 -0.41 836872.0 -91000.0 -0.51 -0.6512 -0.9935 3626925 CBKinase1_016580 Clc1ccc(Cn2ncc3c(NCCN4CCOCC4)ncnc23)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A23 compound treatment 983148.0 61000.0 0.33 775246.0 -153000.0 -0.86 -0.3728 -0.4041 3626926 CBKinase1_016581 COc1ccc2[nH]c(SCC(=O)Nc3cccc(c3)[N+](=O)[O-])nc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 A24 compound treatment 777798.0 -144000.0 -0.79 655744.0 -272000.0 -1.53 -1.6419 -0.9521 3626927 CBKinase1_016582 Cc1ccc(NC(=O)CSc2nnc([nH]2)c3ccccc3)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B01 compound treatment 856663.0 -65500.0 -0.36 843281.0 -84600.0 -0.48 -0.59 -0.9899 3626928 CBKinase1_016583 COc1nnc(c2ccc(N3CCOCC3)c(NC(=O)COc4cccc(C)c4)c2)c5ccccc15 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B02 compound treatment 809397.0 -113000.0 -0.62 904728.0 -23200.0 -0.13 -0.5275 -0.8385 3626929 CBKinase1_016584 Cc1ccc(cc1)c2nnc(SCC(=O)Nc3c(Cl)cc(Cl)cc3Cl)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B03 compound treatment 847992.0 -74100.0 -0.4 878030.0 -49900.0 -0.28 -0.4849 -0.9842 1683802 CBKinase1_016585 COc1ccc(NC(=O)CSc2nnc(N)s2)c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B04 compound treatment 1103159.0 181000.0 0.99 901919.0 -26000.0 -0.15 0.5953 0.5958 3626930 CBKinase1_016586 CS(=O)(=O)N(CC(=O)O)c1ccc(cc1)C2(CC3CC4CC(C3)C2)C4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B05 compound treatment 973416.0 51300.0 0.28 921003.0 -6900.0 -0.04 0.1705 0.6031 3626931 CBKinase1_016587 Oc1ncnc2n(Cc3ccc(Cl)cc3)ncc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B06 compound treatment 957662.0 35500.0 0.19 882505.0 -45400.0 -0.26 -0.0437 -0.1362 3626932 CBKinase1_016588 CCOC(=O)c1c(NC(=O)Cn2cnc3ccccc3c2=O)sc4CCCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B07 compound treatment 984188.0 62100.0 0.34 901303.0 -26600.0 -0.15 0.1336 0.3605 3626933 CBKinase1_016589 FC(F)(F)c1cccc(NC(=O)CCn2nc(c3ccc(Cl)cc3)c4ccccc4c2=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B08 compound treatment 856836.0 -65300.0 -0.36 929105.0 1200.0 0.01 -0.2472 -0.6936 3626934 CBKinase1_016590 OC(=O)c1cc(NS(=O)(=O)c2cccc3cccnc23)ccc1O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B09 compound treatment 898762.0 -23400.0 -0.13 987399.0 59500.0 0.34 0.147 0.4096 3626935 CBKinase1_016591 Ic1ccc(NC(=O)c2cccnc2)c(c1)C(=O)NCC3CCCO3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B10 compound treatment 950889.0 28800.0 0.16 931542.0 3640.0 0.02 0.1256 0.7926 1571215 CBKinase1_016592 Cc1ccc(NC(=O)CSc2nc3cc(Cl)ccc3s2)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B11 compound treatment 282359.0 -640000.0 -3.49 302958.0 -625000.0 -3.52 -4.9605 -1.0 3626936 CBKinase1_016593 CCCOc1ccc(Oc2nc(NCC)nc(OC)n2)nn1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B12 compound treatment 807680.0 -114000.0 -0.62 1012051.0 84100.0 0.47 -0.1064 -0.1357 1126408 CBKinase1_016594 COc1ccc2[nH]c(SCC(=O)NC3CCCC3)nc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B13 mock treatment 1004814.0 82700.0 0.45 925952.0 -1950.0 -0.01 0.3115 0.6897 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B14 mock treatment 1124742.0 203000.0 1.11 944796.0 16900.0 0.1 0.8495 0.7651 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B15 compound treatment 1086175.0 164000.0 0.9 953397.0 25500.0 0.14 0.7349 0.8102 3626937 CBKinase1_016595 Nc1nc(nn1C(=O)c2ccco2)c3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B16 compound treatment 999498.0 77400.0 0.42 952177.0 24300.0 0.14 0.3955 0.8906 3626938 CBKinase1_016596 CC(=O)c1cccc(NC(=O)CCN2C(=O)C3CC=C(Cl)CC3C2=O)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B17 compound treatment 987422.0 65300.0 0.36 1022719.0 94800.0 0.53 0.63 0.9806 3626939 CBKinase1_016597 Cn1c(SCC(=O)Nc2ccccc2Cl)nnc1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B18 compound treatment 913683.0 -8430.0 -0.05 1017047.0 89100.0 0.5 0.3227 0.6396 2068696 CBKinase1_016598 Cc1oc2nc(SCC(=O)N3CCCCC3)nc(N)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B19 compound treatment 1010548.0 88400.0 0.48 950920.0 23000.0 0.13 0.4331 0.8664 3626940 CBKinase1_016599 CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc2nc3NC(=CC(c4ccccc4)n3n2)c5ccc(C)cc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B20 compound treatment 997744.0 75600.0 0.41 964155.0 36200.0 0.2 0.4364 0.9474 3626941 CBKinase1_016600 CCOc1ccc(OCC(=O)Nc2ccc(C)cc2[N+](=O)[O-])cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B21 compound treatment 1107332.0 185000.0 1.01 837345.0 -90600.0 -0.51 0.3541 0.3126 3626942 CBKinase1_016601 Ic1ccc(NC(=O)c2ccco2)c(c1)C(=O)NCc3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B22 compound treatment 685835.0 -236000.0 -1.29 997536.0 69600.0 0.39 -0.6346 -0.4707 3626943 CBKinase1_016602 Cc1ccc(OCC(=O)Oc2cccc(NC3=NS(=O)(=O)c4ccccc34)c2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B23 compound treatment 1084329.0 162000.0 0.89 790920.0 -137000.0 -0.77 0.0802 0.0683 3626944 CBKinase1_016603 Cn1nc(c2ccc(NCc3cccnc3)c(c2)[N+](=O)[O-])c4ccccc4c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 B24 compound treatment 827174.0 -94900.0 -0.52 825790.0 -102000.0 -0.58 -0.7735 -0.9986 3626945 CBKinase1_016604 NC(=O)c1c(NC(=O)Cn2c(=O)oc3ccccc23)sc4CCCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C01 compound treatment 1036595.0 114000.0 0.62 1050429.0 123000.0 0.69 0.9303 0.9988 3626946 CBKinase1_016605 COc1ccc(NC(=O)CC2Nc3ccccc3NC2=O)c(OC)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C02 compound treatment 1012201.0 90100.0 0.49 998787.0 70900.0 0.4 0.6303 0.9947 3626947 CBKinase1_016606 COc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(SC)c3)o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C03 compound treatment 929911.0 7790.0 0.04 863605.0 -64300.0 -0.36 -0.2262 -0.6198 3626948 CBKinase1_016607 CCc1nnc(SCC(=O)Nc2ccccc2C)[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C04 compound treatment 904555.0 -17600.0 -0.1 843684.0 -84200.0 -0.47 -0.4035 -0.8331 3626949 CBKinase1_016608 COc1ccccc1n2c(SCC(=O)Nc3ccccc3C)nc4ccc(I)cc4c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C05 compound treatment 983594.0 61500.0 0.34 868009.0 -59900.0 -0.34 -0.0014 -0.0029 3626950 CBKinase1_016609 COC(=O)c1ccccc1NC(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C06 compound treatment 1058893.0 137000.0 0.75 961049.0 33100.0 0.19 0.6601 0.8576 3626951 CBKinase1_016610 Cc1ccc(NC(=O)CSc2nc(cc(n2)C(F)(F)F)c3cccs3)c(c1)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C07 compound treatment 934727.0 12600.0 0.07 996047.0 68100.0 0.38 0.3203 0.8208 3626952 CBKinase1_016611 CC(Sc1nc(C)cc(=O)[nH]1)C(=O)Nc2cccc3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C08 compound treatment 948384.0 26300.0 0.14 884420.0 -43500.0 -0.25 -0.0719 -0.2532 3626953 CBKinase1_016612 Clc1ccc(NC(=O)CSc2ncn(n2)c3ccccc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C09 compound treatment 955710.0 33600.0 0.18 954341.0 26400.0 0.15 0.235 0.9947 3626954 CBKinase1_016613 COc1ccc(Cl)cc1NC(=O)CCN2C(=O)C3C(C4C=CC3C5CC54)C2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C10 compound treatment 934520.0 12400.0 0.07 884126.0 -43800.0 -0.25 -0.1266 -0.4948 3626955 CBKinase1_016614 CCCc1cc(=O)[nH]c(SCC(=O)Nc2ccc(Cl)c(Cl)c2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C11 mock treatment 1025480.0 103000.0 0.56 949849.0 21900.0 0.12 0.4865 0.8421 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C12 mock treatment 1046908.0 125000.0 0.68 895400.0 -32500.0 -0.18 0.3522 0.4992 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C13 compound treatment 1025572.0 103000.0 0.56 890447.0 -37500.0 -0.21 0.2501 0.4148 3626956 CBKinase1_016615 CC(Sc1nc(C)cc(=O)[nH]1)C(=O)Nc2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C14 compound treatment 916042.0 -6070.0 -0.03 880796.0 -47100.0 -0.27 -0.2112 -0.7893 3626957 CBKinase1_016616 Cc1ccc(cc1)n2c(SCC(=O)Nc3ccccc3c4ccccc4)nc5ccccc5c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C15 mock treatment 1062071.0 140000.0 0.76 958080.0 30200.0 0.17 0.6605 0.8438 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C16 mock treatment 994933.0 72800.0 0.4 984841.0 56900.0 0.32 0.508 0.9944 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C17 compound treatment 891219.0 -30900.0 -0.17 953859.0 26000.0 0.15 -0.0158 -0.071 1551345 CBKinase1_016617 CCOC(=O)CN1C(=O)C(O)(c2c[nH]c3ccccc23)c4ccccc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C18 compound treatment 1007686.0 85600.0 0.47 943127.0 15200.0 0.09 0.391 0.8232 3626958 CBKinase1_016618 COc1cc(ccc1OCC(O)Cn2nc(C)c(Br)c2C)C(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C19 compound treatment 1020984.0 98900.0 0.54 994965.0 67100.0 0.38 0.6489 0.9848 3626959 CBKinase1_016619 CCOC(=O)c1ccc(NC(=O)C2CC=CCC2(C)C(=O)O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C20 compound treatment 1118227.0 196000.0 1.07 860855.0 -67100.0 -0.38 0.4898 0.4314 3626960 CBKinase1_016620 CC(Sc1nc(O)c(c2ccccc2)c(=O)[nH]1)C(=O)Nc3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C21 compound treatment 1059443.0 137000.0 0.75 952473.0 24600.0 0.14 0.6281 0.8238 3626961 CBKinase1_016621 COc1ccc(OC)c(NC(=O)CSc2nc(cc(=O)[nH]2)c3ccccc3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C22 compound treatment 860307.0 -61800.0 -0.34 901396.0 -26500.0 -0.15 -0.3443 -0.9328 3626962 CBKinase1_016622 CCOC(=O)c1c(C)c(C)sc1NC(=O)C(C)Oc2ccccc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C23 compound treatment 839872.0 -82200.0 -0.45 811953.0 -116000.0 -0.65 -0.7796 -0.9832 3626963 CBKinase1_016623 Cc1nn(C)cc1CNC(=O)c2cnn3c(cc(nc23)c4ccc(C)cc4)C(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 C24 compound treatment 880085.0 -42000.0 -0.23 928762.0 856.0 0.0 -0.1589 -0.6921 3626964 CBKinase1_016624 CC(Sc1nc2ccccc2c(=O)[nH]1)C(=O)Nc3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D01 compound treatment 804501.0 -118000.0 -0.64 908607.0 -19300.0 -0.11 -0.531 -0.8153 3626965 CBKinase1_016625 COC(=O)c1ccc(NC(=O)CCn2nc(c3ccccc3)c4ccccc4c2=O)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D02 compound treatment 856787.0 -65300.0 -0.36 905628.0 -22300.0 -0.13 -0.341 -0.9018 3626966 CBKinase1_016626 Cc1ccc2nc(Nc3nc(=O)cc(CSc4nc5ccccc5s4)[nH]3)nc(C)c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D03 compound treatment 803753.0 -118000.0 -0.65 918733.0 -9170.0 -0.05 -0.4935 -0.7612 3626967 CBKinase1_016627 Ic1ccc(NC(=O)c2ccco2)c(c1)C(=O)NCCN3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D04 compound treatment 902329.0 -19800.0 -0.11 897371.0 -30500.0 -0.17 -0.1981 -0.9748 3626968 CBKinase1_016628 COc1ccc(cc1OC)S(=O)(=O)N(C)CC(=O)N2CCOCC2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D05 compound treatment 958828.0 36700.0 0.2 906159.0 -21700.0 -0.12 0.055 0.2343 3626969 CBKinase1_016629 Cc1ccc(NC(=O)CSc2nnc[nH]2)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D06 compound treatment 923470.0 1350.0 0.01 883708.0 -44200.0 -0.25 -0.1709 -0.6858 3626970 CBKinase1_016630 O=C(N1CCOCC1)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D07 compound treatment 858355.0 -63800.0 -0.35 886177.0 -41700.0 -0.24 -0.4125 -0.9818 1171350 CBKinase1_016631 OC1(CC(=O)c2ccco2)C(=O)N(Cc3cccc4ccccc34)c5ccccc51 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D08 compound treatment 790816.0 -131000.0 -0.72 966927.0 39000.0 0.22 -0.3514 -0.4686 3626971 CBKinase1_016632 CCC(Sc1nc(C)cc(=O)[nH]1)C(=O)Nc2ccccc2C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D09 compound treatment 910594.0 -11500.0 -0.06 892161.0 -35700.0 -0.2 -0.1869 -0.8857 3626972 CBKinase1_016633 COc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2c4ccc(C)cc4)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D10 compound treatment 934269.0 12200.0 0.07 877805.0 -50100.0 -0.28 -0.1528 -0.5266 3026141 CBKinase1_016634 COC(=O)c1ccc(CN(Cc2ccc(o2)C(=O)OC)C(C)(C)C)o1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D11 mock treatment 908564.0 -13600.0 -0.07 923065.0 -4840.0 -0.03 -0.0716 -0.9081 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D12 mock treatment 996061.0 73900.0 0.4 1036914.0 109000.0 0.61 0.7199 0.9792 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D13 compound treatment 978736.0 56600.0 0.31 901108.0 -26800.0 -0.15 0.1118 0.3249 3626973 CBKinase1_016635 CCn1cc(cn1)C(=O)NC(=S)Nc2sc3CCCCCCc3c2C(=O)OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D14 compound treatment 800231.0 -122000.0 -0.67 933155.0 5250.0 0.03 -0.4496 -0.675 3626974 CBKinase1_016636 Ic1ccc(NC(=O)c2cccnc2)c(c1)C(=O)NCc3ccco3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D15 mock treatment 1006895.0 84800.0 0.46 945648.0 17700.0 0.1 0.398 0.8405 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D16 mock treatment 978794.0 56700.0 0.31 936385.0 8480.0 0.05 0.2526 0.8068 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D17 compound treatment 942996.0 20900.0 0.11 917899.0 -10000.0 -0.06 0.0407 0.3202 3626975 CBKinase1_016637 Cc1ccc(cc1)c2nnc(SCC(=O)Nc3ccc(Br)c(C)c3C)o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D18 compound treatment 948133.0 26000.0 0.14 978578.0 50700.0 0.29 0.3024 0.948 3626976 CBKinase1_016638 COc1cc(NC(=O)C2CC=CCC2C(=O)O)ccc1NC(=O)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D19 compound treatment 915141.0 -6980.0 -0.04 892766.0 -35100.0 -0.2 -0.167 -0.8279 3626977 CBKinase1_016639 CN(CC(=O)Nc1ccc(F)c(Cl)c1)S(=O)(=O)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D20 compound treatment 974845.0 52700.0 0.29 972078.0 44200.0 0.25 0.3796 0.9974 3626978 CBKinase1_016640 CCc1cc2c(=O)n(CC(=O)Nc3cc(OC)ccc3OC)cnc2s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D21 compound treatment 910142.0 -12000.0 -0.07 866117.0 -61800.0 -0.35 -0.2925 -0.8254 3626979 CBKinase1_016641 Nc1cc(N)nc(SCC(=O)Nc2ccc3ccccc3c2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D22 compound treatment 808053.0 -114000.0 -0.62 761659.0 -166000.0 -0.94 -1.1029 -0.9803 1263877 CBKinase1_016642 COc1ccc(OC)c(c1)C(=O)c2ccc(cc2)C(=O)NCc3nc(cs3)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D23 compound treatment 849301.0 -72800.0 -0.4 801881.0 -126000.0 -0.71 -0.7834 -0.9624 3626980 CBKinase1_016643 COc1ccccc1NC(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 D24 compound treatment 900005.0 -22100.0 -0.12 969746.0 41800.0 0.24 0.0814 0.3072 3626981 CBKinase1_016644 COc1cc(NC(=O)C2C(C3CC2C=C3)C(=O)O)ccc1NC(=O)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E01 mock treatment 503057.0 -419000.0 -2.29 817869.0 -110000.0 -0.62 -2.0563 -0.8675 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E02 mock treatment 715136.0 -207000.0 -1.13 791969.0 -136000.0 -0.77 -1.3408 -0.9821 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E03 compound treatment 634683.0 -287000.0 -1.57 861907.0 -66000.0 -0.37 -1.3727 -0.8511 1507592 CBKinase1_016645 Cc1ccc(cc1)n2c(SCC(=O)Nc3cccc(F)c3)nc4ccccc4c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E04 compound treatment 643197.0 -279000.0 -1.52 693308.0 -235000.0 -1.32 -2.0118 -0.9975 3626982 CBKinase1_016646 Clc1ccc(NC(=O)CSC2=NC(CC(=O)N2)c3ccccc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E05 compound treatment 586788.0 -335000.0 -1.83 657027.0 -271000.0 -1.53 -2.3741 -0.9959 3626983 CBKinase1_016647 OC1(CC(=O)c2ccc3OCCOc3c2)C(=O)N(CCCC#N)c4ccccc41 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E06 compound treatment 649129.0 -273000.0 -1.49 679513.0 -248000.0 -1.4 -2.0438 -0.9995 1322745 CBKinase1_016648 Cc1ccc(o1)C(=O)CC2(O)C(=O)N(Cc3ccccc3)c4ccc(Br)cc42 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E07 compound treatment 829958.0 -92200.0 -0.5 741422.0 -186000.0 -1.05 -1.099 -0.9431 1392585 CBKinase1_016649 COc1ccc2[nH]c(SCC(=O)NC3CCCCC3)nc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E08 compound treatment 763683.0 -158000.0 -0.86 844250.0 -83700.0 -0.47 -0.945 -0.9593 3626984 CBKinase1_016650 COc1ccc(C)cc1NC(=O)c2ccc(OCC(=O)Nc3cc(Cl)ccc3Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E09 mock treatment 720775.0 -201000.0 -1.1 745489.0 -182000.0 -1.03 -1.5043 -0.9994 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E10 mock treatment 852226.0 -69900.0 -0.38 756136.0 -172000.0 -0.97 -0.9544 -0.9171 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E11 compound treatment 837741.0 -84400.0 -0.46 773392.0 -155000.0 -0.87 -0.9416 -0.9557 3626985 CBKinase1_016651 COc1ccc(cc1)C(CC(=O)O)NC(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E12 compound treatment 909341.0 -12800.0 -0.07 1034721.0 107000.0 0.6 0.3764 0.621 3626986 CBKinase1_016652 COc1cc(ccc1OCC(O)Cn2nc(C)cc2C)C(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E13 compound treatment 732525.0 -190000.0 -1.04 881666.0 -46200.0 -0.26 -0.9162 -0.8584 3626987 CBKinase1_016653 COC(=O)c1ccc2c(=O)n(c(SCC(=O)Nc3ccccc3)nc2c1)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E14 compound treatment 876417.0 -45700.0 -0.25 774686.0 -153000.0 -0.86 -0.7871 -0.8756 3626988 CBKinase1_016654 OC(=O)COc1ccc(cc1)C(=O)Nc2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E15 compound treatment 924465.0 2350.0 0.01 821208.0 -107000.0 -0.6 -0.4162 -0.6919 3626989 CBKinase1_016655 OC1=C(C(N(CCCn2ccnc2)C1=O)c3cccs3)C(=O)c4cc5ccccc5o4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E16 compound treatment 845342.0 -76800.0 -0.42 778362.0 -150000.0 -0.84 -0.8924 -0.948 3025183 CBKinase1_016656 CC(Sc1ccc(Br)c2cccc(C(=O)O)c12)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E17 mock treatment 677614.0 -245000.0 -1.33 797489.0 -130000.0 -0.74 -1.4637 -0.9605 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E18 mock treatment 941160.0 19000.0 0.1 791454.0 -136000.0 -0.77 -0.4703 -0.606 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E19 compound treatment 726861.0 -195000.0 -1.07 719824.0 -208000.0 -1.17 -1.5831 -0.9989 3626990 CBKinase1_016657 OC1=C(C(N(CCc2ccccc2)C1=O)c3ccco3)C(=O)c4cc5ccccc5o4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E20 compound treatment 754198.0 -168000.0 -0.92 697797.0 -230000.0 -1.3 -1.5654 -0.9856 3626991 CBKinase1_016658 O=C1N(OS(=O)(=O)c2cccc3cccnc23)C(=O)c4cccc5cccc1c45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E21 compound treatment 640654.0 -281000.0 -1.54 658050.0 -270000.0 -1.52 -2.1621 -1.0 3626992 CBKinase1_016659 Cc1ccc(cc1S(=O)(=O)N2CCN(CCO)CC2)c3nn(C)c(=O)c4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E22 compound treatment 805172.0 -117000.0 -0.64 727049.0 -201000.0 -1.13 -1.252 -0.9633 3626993 CBKinase1_016660 COC(=O)c1ccccc1NC(=O)CSC2=NC(CC(=O)N2)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E23 compound treatment 646839.0 -275000.0 -1.5 641515.0 -286000.0 -1.61 -2.2041 -0.9994 3626994 CBKinase1_016661 Cn1c(=O)n(C)c2nc(NCCN3CCOCC3)[nH]c2c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 E24 compound treatment 508342.0 -414000.0 -2.26 585055.0 -343000.0 -1.93 -2.9638 -0.997 3626995 CBKinase1_016662 CC(=O)c1c(C)nn(CC(O)COc2ccc3ccccc3c2)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F01 mock treatment 696609.0 -226000.0 -1.23 752760.0 -175000.0 -0.99 -1.5686 -0.994 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F02 mock treatment 669435.0 -253000.0 -1.38 847826.0 -80100.0 -0.45 -1.2946 -0.8919 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F03 compound treatment 789635.0 -132000.0 -0.72 885728.0 -42200.0 -0.24 -0.6795 -0.8925 1310502 CBKinase1_016663 COc1ccccc1NC(=S)NCc2ccc(cc2)S(=O)(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F04 compound treatment 722962.0 -199000.0 -1.09 896465.0 -31400.0 -0.18 -0.8941 -0.8116 1577198 CBKinase1_016664 COc1ccccc1NC(=O)C2=C(C)Nc3ncnn3C2c4ccccn4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F05 compound treatment 719284.0 -203000.0 -1.11 890990.0 -36900.0 -0.21 -0.9302 -0.8255 3626996 CBKinase1_016665 CCOC(=O)C(Sc1nc(nc(n1)N(C)C)N(C)C)C(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F06 compound treatment 801047.0 -121000.0 -0.66 831873.0 -96000.0 -0.54 -0.8501 -0.9951 3626997 CBKinase1_016666 COC(=O)c1c(NC(=O)c2nc3nc(C)cc(C(F)F)n3n2)sc4CCCc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F07 compound treatment 817257.0 -105000.0 -0.57 856671.0 -71200.0 -0.4 -0.6887 -0.9849 3626998 CBKinase1_016667 OC(COc1ccc2ccccc2c1Br)Cn3cnc(c3)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F08 compound treatment 846733.0 -75400.0 -0.41 848863.0 -79000.0 -0.45 -0.606 -0.9992 3626999 CBKinase1_016668 COc1ccc(cc1[N+](=O)[O-])C(=O)NCCc2c[nH]c3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F09 mock treatment 793182.0 -129000.0 -0.7 855566.0 -72300.0 -0.41 -0.7861 -0.9663 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F10 mock treatment 1018757.0 96600.0 0.53 888368.0 -39500.0 -0.22 0.2155 0.3762 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F11 compound treatment 996782.0 74700.0 0.41 890907.0 -37000.0 -0.21 0.1408 0.3075 3627000 CBKinase1_016669 Cc1ccc(cc1)n2c(SCC(=O)Nc3ccc(cc3)C(=O)N)nnc2c4ccc(Cl)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F12 compound treatment 849418.0 -72700.0 -0.4 859063.0 -68800.0 -0.39 -0.555 -0.9999 3627001 CBKinase1_016670 CCn1c(SCC(=O)Nc2cccc(C)c2C)nnc1c3ccc(Cl)c(Cl)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F13 compound treatment 946798.0 24700.0 0.13 822759.0 -105000.0 -0.59 -0.3238 -0.5327 3627002 CBKinase1_016671 Cc1cc(C(F)F)n2nc(nc2n1)C(=O)Nc3cccc(c3)S(=O)(=O)N4CCOCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F14 compound treatment 774757.0 -147000.0 -0.8 843828.0 -84100.0 -0.47 -0.904 -0.9681 3627003 CBKinase1_016672 [O-][N+](=O)c1cc(ccc1NCc2cccnc2)c3n[nH]c(=O)c4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F15 compound treatment 989862.0 67700.0 0.37 932630.0 4720.0 0.03 0.2804 0.7561 3627004 CBKinase1_016673 CCOC(=O)c1c(NC(=O)c2cccc(OC(=O)C)c2)scc1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F16 compound treatment 695538.0 -227000.0 -1.24 786741.0 -141000.0 -0.8 -1.4373 -0.9772 3627005 CBKinase1_016674 CC(Sc1nnc(C)[nH]1)C(=O)Nc2ccc(C)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F17 mock treatment 938604.0 16500.0 0.09 802463.0 -125000.0 -0.71 -0.4363 -0.6121 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F18 mock treatment 704423.0 -218000.0 -1.19 817177.0 -111000.0 -0.62 -1.2817 -0.9548 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F19 compound treatment 662865.0 -259000.0 -1.42 710042.0 -218000.0 -1.23 -1.8691 -0.9975 3627006 CBKinase1_016675 COc1ccc(cc1)c2nnc(SCC(=O)Nc3cccc(SC)c3)n2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F20 compound treatment 753794.0 -168000.0 -0.92 772551.0 -155000.0 -0.88 -1.269 -0.9997 3627007 CBKinase1_016676 Cc1ccc(cc1)S(=O)(=O)NCC(=O)N2CCN(CC2)c3ccccn3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F21 compound treatment 707566.0 -215000.0 -1.17 736511.0 -191000.0 -1.08 -1.5911 -0.9992 3627008 CBKinase1_016677 COc1ccc([N+](=O)[O-])c(NC(=O)c2cnn3c(cc(nc23)c4ccc(C)cc4)C(F)F)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F22 compound treatment 658028.0 -264000.0 -1.44 675679.0 -252000.0 -1.42 -2.0248 -1.0 3627009 CBKinase1_016678 Clc1ccccc1C(=O)Nc2ccc(I)cc2C(=O)NCCN3CCOCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F23 compound treatment 744307.0 -178000.0 -0.97 663035.0 -265000.0 -1.49 -1.7421 -0.9783 3627010 CBKinase1_016679 Fc1ccc(cc1)C(=O)CSc2nnc(c3cccnc3)n2c4ccc(Br)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 F24 compound treatment 693077.0 -229000.0 -1.25 580495.0 -347000.0 -1.96 -2.2688 -0.9765 3627011 CBKinase1_016680 Cc1ccc(NC(=O)CSc2nnc([nH]2)c3ccco3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G01 compound treatment 793689.0 -128000.0 -0.7 841199.0 -86700.0 -0.49 -0.8414 -0.9844 3627012 CBKinase1_016681 CCn1c(SCC(=O)Nc2c(C)cc(C)cc2C)nnc1c3ccccc3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G02 compound treatment 1147826.0 226000.0 1.23 1221038.0 293000.0 1.65 2.0396 0.9896 3627013 CBKinase1_016682 OC(=O)COc1ccc(Cl)cc1C2C3=C(CCCC3=O)NC4=C2C(=O)CCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G03 mock treatment 759551.0 -163000.0 -0.89 882531.0 -45400.0 -0.26 -0.8084 -0.8753 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G04 mock treatment 805714.0 -116000.0 -0.64 885944.0 -42000.0 -0.24 -0.6166 -0.9093 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G05 compound treatment 637252.0 -285000.0 -1.56 655505.0 -272000.0 -1.54 -2.1854 -1.0 3627014 CBKinase1_016683 Cc1c(OCC(=O)Nc2ccc3OCCOc3c2)ccc4c5ccccc5c(=O)oc14 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G06 compound treatment 810845.0 -111000.0 -0.61 890853.0 -37100.0 -0.21 -0.5772 -0.8986 3627015 CBKinase1_016684 CCn1c(SCC(=O)Nc2cc(Cl)ccc2Cl)nnc1c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G07 compound treatment 952715.0 30600.0 0.17 1035244.0 107000.0 0.61 0.5459 0.8698 3627016 CBKinase1_016685 CCC(Sc1nc(C)cc(C)n1)C(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G08 compound treatment 843653.0 -78500.0 -0.43 843790.0 -84100.0 -0.47 -0.6382 -0.9987 3627017 CBKinase1_016686 Cc1ccc(cc1NC(=O)c2ccc(NC(=O)C3(CCOCC3)c4ccccc4)cc2)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G09 compound treatment 870460.0 -51700.0 -0.28 947181.0 19300.0 0.11 -0.1226 -0.4057 3627018 CBKinase1_016687 COc1ccc(OC)c(c1)C(=O)CSc2nnc(c3ccncc3)n2c4ccc(C)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G10 compound treatment 934867.0 12800.0 0.07 916388.0 -11500.0 -0.06 0.0033 0.0348 3627019 CBKinase1_016688 COC(=O)C1(CCC2(C)C(C1)OC(=O)c3cc4ccccc4oc3=O)C2(C)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G11 compound treatment 923813.0 1700.0 0.01 899424.0 -28500.0 -0.16 -0.107 -0.6652 3627020 CBKinase1_016689 CCn1c(SCC(=O)Nc2ccc(Cl)cc2C)nnc1c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G12 compound treatment 905243.0 -16900.0 -0.09 932085.0 4180.0 0.02 -0.0485 -0.5099 3627021 CBKinase1_016690 CCOc1ccccc1NC(=O)CSc2nc3ccccc3c(=O)n2c4ccc(Cl)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G13 compound treatment 838089.0 -84000.0 -0.46 878987.0 -48900.0 -0.28 -0.5194 -0.9703 3627022 CBKinase1_016691 Cc1ccc(cc1)n2c(SCC(=O)Nc3cccc(C)c3C)nc4ccccc4c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G14 compound treatment 989515.0 67400.0 0.37 934517.0 6610.0 0.04 0.2865 0.7748 3627023 CBKinase1_016692 Cc1c(O)ccc(c2n[nH]cc2c3nncn3c4ccccc4)c1O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G15 compound treatment 908340.0 -13800.0 -0.08 1004671.0 76800.0 0.43 0.2528 0.5756 3627024 CBKinase1_016693 Cc1ccc(cc1S(=O)(=O)NCCN2CCOCC2)c3nn(C)c(=O)c4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G16 compound treatment 953731.0 31600.0 0.17 911837.0 -16100.0 -0.09 0.058 0.2976 3627025 CBKinase1_016694 Cc1nonc1OCCNc2cc(ccc2[N+](=O)[O-])N3CCCC3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G17 compound treatment 924683.0 2570.0 0.01 929890.0 1980.0 0.01 0.0178 0.9938 1335693 CBKinase1_016695 COc1cc2c(cc1NC(=O)CSc3nnc(N)s3)oc4ccccc42 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G18 compound treatment 848079.0 -74000.0 -0.4 873321.0 -54600.0 -0.31 -0.5034 -0.9909 3627026 CBKinase1_016696 Clc1ccc(cc1)c2nn(CCC(=O)Nc3ccccc3)c(=O)c4ccccc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G19 mock treatment 785953.0 -136000.0 -0.74 854237.0 -73700.0 -0.42 -0.8193 -0.9622 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G20 mock treatment 817538.0 -105000.0 -0.57 780488.0 -147000.0 -0.83 -0.9913 -0.9832 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G21 compound treatment 772626.0 -149000.0 -0.82 793347.0 -135000.0 -0.76 -1.1134 -0.9993 3627027 CBKinase1_016697 CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)S(=O)(=O)c3ccc(F)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G22 compound treatment 721714.0 -200000.0 -1.09 834771.0 -93100.0 -0.52 -1.1448 -0.9434 3627028 CBKinase1_016698 Cc1ccc(cc1CNC(=O)CN2C(=O)c3ccccc3C2=O)c4nn(C)c(=O)c5ccccc45 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G23 compound treatment 688809.0 -233000.0 -1.27 735425.0 -192000.0 -1.08 -1.6678 -0.9968 3627029 CBKinase1_016699 CCc1cc(C(=O)OC)c(NC(=O)CC2Nc3cc(C)c(C)cc3NC2=O)s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 G24 compound treatment 434413.0 -488000.0 -2.66 703783.0 -224000.0 -1.26 -2.776 -0.9419 3627030 CBKinase1_016700 CC(Sc1ncn[nH]1)C(=O)Nc2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H01 compound treatment 799531.0 -123000.0 -0.67 907355.0 -20600.0 -0.12 -0.5551 -0.8173 3627031 CBKinase1_016701 Cc1ccc(cc1)n2c(SCC(=O)Nc3ccc(F)c(F)c3)nnc2c4ccc(Cl)cc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H02 compound treatment 793124.0 -129000.0 -0.7 897488.0 -30400.0 -0.17 -0.6192 -0.8543 3627032 CBKinase1_016702 CC(=O)Nc1ccc(NC(=O)CC2Sc3ccc(cc3NC2=O)C(F)(F)F)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H03 mock treatment 803730.0 -118000.0 -0.65 866602.0 -61300.0 -0.35 -0.7014 -0.957 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H04 mock treatment 857526.0 -64600.0 -0.35 920497.0 -7410.0 -0.04 -0.2789 -0.7854 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H05 compound treatment 873399.0 -48700.0 -0.27 888293.0 -39600.0 -0.22 -0.346 -0.9962 3627033 CBKinase1_016703 FC(F)(F)c1ccccc1NC(=O)CCCN2C(=O)c3cccc4cccc(C2=O)c34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H06 compound treatment 879741.0 -42400.0 -0.23 931844.0 3940.0 0.02 -0.1479 -0.6363 3627034 CBKinase1_016704 Cc1ccc(cc1)c2cc(C(F)F)n3ncc(C(=O)NCCCN4CCOCC4)c3n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H07 compound treatment 877306.0 -44800.0 -0.24 944900.0 17000.0 0.1 -0.1053 -0.4006 3627035 CBKinase1_016705 COc1ccc(CCNC(=O)c2ccc(o2)c3cccc(c3)[N+](=O)[O-])cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H08 compound treatment 871684.0 -50400.0 -0.28 934817.0 6910.0 0.04 -0.1672 -0.6011 3627036 CBKinase1_016706 CCc1nnc(SCC(=O)Nc2ccc(Br)cc2)[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H09 compound treatment 947352.0 25200.0 0.14 941207.0 13300.0 0.07 0.1504 0.9591 3627037 CBKinase1_016707 Cc1cc2NC(CC(=O)Nc3ccc(Cl)cc3Cl)C(=O)Nc2cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H10 compound treatment 935894.0 13800.0 0.08 967781.0 39900.0 0.22 0.2121 0.895 1984162 CBKinase1_016708 OC(=O)C1CCCCC1C(=O)NCCc2ccncc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H11 compound treatment 933233.0 11100.0 0.06 985526.0 57600.0 0.32 0.2726 0.825 3627038 CBKinase1_016709 Cc1cccc(c1)c2nnc(SCC(=O)Nc3c(Cl)cc(Cl)cc3Cl)o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H12 compound treatment 964211.0 42100.0 0.23 1066808.0 139000.0 0.78 0.7161 0.8776 3627039 CBKinase1_016710 O=C(COc1ccc2ccccc2c1)Nc3ccccc3c4nc5ccccc5s4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H13 compound treatment 915731.0 -6390.0 -0.03 992072.0 64200.0 0.36 0.2311 0.636 3627040 CBKinase1_016711 CCn1c(SCC(=O)Nc2c(Cl)cc(Cl)cc2Cl)nnc1c3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H14 compound treatment 902300.0 -19800.0 -0.11 962497.0 34600.0 0.19 0.0614 0.2752 3627041 CBKinase1_016712 COc1ccccc1CNC(=O)c2cnn3c(cc(C)nc23)C(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H15 compound treatment 1037186.0 115000.0 0.63 1058494.0 131000.0 0.74 0.9647 0.9969 3627042 CBKinase1_016713 COC(=O)Cc1c(C)c2cc(Cl)c(OC(C)C(=O)C)cc2oc1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H16 compound treatment 941402.0 19300.0 0.11 982325.0 54400.0 0.31 0.2913 0.8984 3627043 CBKinase1_016714 OC(=O)CNC(=O)C1COc2ccccc2O1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H17 compound treatment 941408.0 19300.0 0.11 986015.0 58100.0 0.33 0.3061 0.8896 3627044 CBKinase1_016715 CN(C)C(=O)CSc1nc(O)c2ccccc2n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H18 compound treatment 853501.0 -68600.0 -0.37 945263.0 17400.0 0.1 -0.1957 -0.5055 3627045 CBKinase1_016716 O=C(CCn1cnc2ccccc2c1=O)Nc3sc4CCCCc4c3C#N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H19 mock treatment 861839.0 -60300.0 -0.33 893356.0 -34600.0 -0.19 -0.3704 -0.9686 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H20 mock treatment 845238.0 -76900.0 -0.42 873981.0 -53900.0 -0.3 -0.5117 -0.9874 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H21 compound treatment 881733.0 -40400.0 -0.22 864412.0 -63500.0 -0.36 -0.409 -0.9729 3627046 CBKinase1_016717 Cc1ccc(cc1)c2nn(CC(=O)NCCN3CCOCC3)c(=O)c4ccccc24 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H22 compound treatment 851937.0 -70200.0 -0.38 811347.0 -117000.0 -0.66 -0.7355 -0.967 3627047 CBKinase1_016718 COc1ccc(cc1)c2cc(=O)[nH]c(SCC(=O)Nc3ccc(Oc4ccccc4)cc3)n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H23 compound treatment 865719.0 -56400.0 -0.31 868754.0 -59200.0 -0.33 -0.4535 -0.9992 3627048 CBKinase1_016719 CCn1c(SCC(=O)Nc2cccc(c2)C(F)(F)F)nnc1c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 H24 compound treatment 800760.0 -121000.0 -0.66 1194932.0 267000.0 1.51 0.5957 0.3623 3627049 CBKinase1_016720 Cn1c(SCC(=O)Nc2ccc(I)cc2)nnc1c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I01 compound treatment 1055491.0 133000.0 0.73 1036735.0 109000.0 0.61 0.9486 0.9964 3627050 CBKinase1_016721 Cc1cc(Br)c(NC(=O)CSc2nnc(c3ccc(Cl)cc3)n2C)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I02 compound treatment 999883.0 77800.0 0.42 991933.0 64000.0 0.36 0.5554 0.9967 3627051 CBKinase1_016722 CC(=O)Nc1ccc(Nc2ncnc3n(Cc4ccc(Cl)cc4)ncc23)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I03 compound treatment 972886.0 50800.0 0.28 1011453.0 83500.0 0.47 0.529 0.9681 1308939 CBKinase1_016723 Cc1ccc(cc1)c2csc3nc(SCC(=O)O)n(c4ccccc4)c(=O)c23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I04 compound treatment 1003229.0 81100.0 0.44 1033907.0 106000.0 0.6 0.7356 0.9891 3627052 CBKinase1_016724 CN(C)C(=O)CSc1nc(O)c2c3CCCCc3sc2n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I05 mock treatment 1079445.0 157000.0 0.86 1065980.0 138000.0 0.78 1.1577 0.9988 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I06 mock treatment 1117695.0 196000.0 1.07 1038765.0 111000.0 0.62 1.1969 0.9674 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I07 compound treatment 1075979.0 154000.0 0.84 1069118.0 141000.0 0.8 1.1568 0.9996 3627053 CBKinase1_016725 CCc1cc(C(=O)OC)c(NC(=O)CC2Sc3ccc(cc3NC2=O)C(F)(F)F)s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I08 compound treatment 1122374.0 200000.0 1.09 1088450.0 161000.0 0.9 1.4129 0.9956 3627054 CBKinase1_016726 OC(CCN1C(=O)c2ccccc2C1=O)C[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I09 compound treatment 1110699.0 189000.0 1.03 1129215.0 201000.0 1.13 1.5303 0.9988 3627055 CBKinase1_016727 OC(=O)CCSc1nnc2c3ccccc3[nH]c2n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I10 compound treatment 1116789.0 195000.0 1.06 1071066.0 143000.0 0.81 1.3221 0.9908 3627056 CBKinase1_016728 CCc1ccc(cc1)S(=O)(=O)NCC(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I11 compound treatment 1149132.0 227000.0 1.24 1119773.0 192000.0 1.08 1.6411 0.9977 3627057 CBKinase1_016729 CC(C)c1cc(Br)ccc1NC(=O)CSc2nnc(o2)c3ccc(C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I12 compound treatment 1045523.0 123000.0 0.67 1108800.0 181000.0 1.02 1.1974 0.9798 3627058 CBKinase1_016730 Brc1ccc(NC(=O)CSc2nnc([nH]2)c3ccccc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I13 compound treatment 1128798.0 207000.0 1.13 1058397.0 130000.0 0.74 1.318 0.9785 1430416 CBKinase1_016731 Cc1ccc(o1)C(=O)CC2(O)C(=O)N(Cc3ccccc3Cl)c4ccccc42 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I14 compound treatment 1135893.0 214000.0 1.17 1083100.0 155000.0 0.87 1.4438 0.9899 3627059 CBKinase1_016732 COC(=O)c1ccccc1NC(=O)CSc2nc3cc(C)ccc3[nH]2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I15 compound treatment 1147951.0 226000.0 1.23 1099550.0 172000.0 0.97 1.5559 0.9928 3627060 CBKinase1_016733 Cn1c(SCC(=O)Nc2cc(Cl)c(Cl)cc2Cl)nnc1c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I16 compound treatment 1015104.0 93000.0 0.51 1067736.0 140000.0 0.79 0.9163 0.9774 3627061 CBKinase1_016734 Cc1cc(C(F)F)n2nc(nc2n1)C(=O)Nc3ccc(Cl)cc3C(=O)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I17 compound treatment 1119159.0 197000.0 1.08 1126629.0 199000.0 1.12 1.5527 0.9998 3627062 CBKinase1_016735 OCCN1CCN(CC1)C(=O)c2cc(I)ccc2NC(=O)c3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I18 compound treatment 1131937.0 210000.0 1.15 1018658.0 90800.0 0.51 1.1717 0.934 3627063 CBKinase1_016736 COc1ccc(cc1CNC(=O)Nc2ccccc2)c3nn(C)c(=O)c4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I19 compound treatment 1103238.0 181000.0 0.99 1002686.0 74800.0 0.42 0.9972 0.9277 3627064 CBKinase1_016737 CCCCn1c2ccccc2c3nnc(SCCN4CCOCC4)nc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I20 compound treatment 667540.0 -255000.0 -1.39 644438.0 -283000.0 -1.6 -2.1126 -0.9976 3627065 CBKinase1_016738 OC1(CC(=O)c2ccccn2)C(=O)N(CCCC#N)c3ccccc31 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I21 mock treatment 1071438.0 149000.0 0.82 959780.0 31900.0 0.18 0.7035 0.8427 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I22 mock treatment 1000316.0 78200.0 0.43 962463.0 34600.0 0.19 0.4396 0.9368 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I23 compound treatment 949373.0 27300.0 0.15 910151.0 -17800.0 -0.1 0.0345 0.1921 3627066 CBKinase1_016739 NC(=O)C1(CCN(CC1)C(=O)CSc2nc3ccccc3s2)N4CCCCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 I24 compound treatment 939072.0 17000.0 0.09 912233.0 -15700.0 -0.09 0.003 0.0234 3627067 CBKinase1_016740 CC(Sc1nc(c(C#N)c(=O)[nH]1)c2ccccc2)C(=O)Nc3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J01 compound treatment 864376.0 -57700.0 -0.32 988138.0 60200.0 0.34 0.0172 0.037 3627068 CBKinase1_016741 COCCNS(=O)(=O)c1cc(ccc1C)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J02 compound treatment 903838.0 -18300.0 -0.1 928175.0 269.0 0.0 -0.0695 -0.6963 1242552 CBKinase1_016742 Cc1ccc(o1)C(=O)CC2(O)C(=O)N(CC#C)c3ccccc32 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J03 compound treatment 855443.0 -66700.0 -0.36 1034196.0 106000.0 0.6 0.1662 0.2371 3627069 CBKinase1_016743 COc1cccc(NC(=O)CC2COc3ccccc3O2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J04 compound treatment 937206.0 15100.0 0.08 900191.0 -27700.0 -0.16 -0.0522 -0.2956 1732831 CBKinase1_016744 C(Nc1ncnc2scc(c3ccccc3)c12)C4CCCO4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J05 mock treatment 907393.0 -14700.0 -0.08 1037795.0 110000.0 0.62 0.3811 0.6102 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J06 mock treatment 976272.0 54200.0 0.3 969636.0 41700.0 0.24 0.3754 0.9936 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J07 compound treatment 1044151.0 122000.0 0.67 1008570.0 80700.0 0.45 0.7926 0.9826 1860995 CBKinase1_016745 COc1ccc(OCC(=O)Nc2ccccc2C(=O)Nc3ccccc3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J08 compound treatment 1035076.0 113000.0 0.62 1038709.0 111000.0 0.62 0.8777 1.0 3627070 CBKinase1_016746 Cn1c(COc2cccc3cccnc23)nnc1SCC(=O)N 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J09 compound treatment 1106602.0 184000.0 1.01 1092347.0 164000.0 0.93 1.3676 0.9991 3627071 CBKinase1_016747 CN(C)c1nc(SC(C(=O)C)C(=O)Nc2ccccc2)nc(n1)N(C)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J10 compound treatment 944414.0 22300.0 0.12 1051258.0 123000.0 0.7 0.5777 0.8185 3627072 CBKinase1_016748 COc1ccc(cc1)C(=O)NC(CC(=O)O)c2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J11 compound treatment 1101042.0 179000.0 0.98 1131597.0 204000.0 1.15 1.5026 0.9968 3627073 CBKinase1_016749 [O-][N+](=O)c1cc(ccc1NCc2cccnc2)C(=O)Nc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J12 compound treatment 1093990.0 172000.0 0.94 1164053.0 236000.0 1.33 1.6047 0.9854 3627074 CBKinase1_016750 Cc1ccc(OCC(=O)Nc2cc3nn(nc3cc2Cl)c4ccccc4)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J13 compound treatment 1123243.0 201000.0 1.1 1068919.0 141000.0 0.79 1.3385 0.9874 3627075 CBKinase1_016751 Oc1nc(CSc2nnc(c3cccnc3)n2C4CCCCC4)nc5ccccc15 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J14 compound treatment 1084557.0 162000.0 0.89 1067868.0 140000.0 0.79 1.1849 0.9983 3627076 CBKinase1_016752 Cc1ccc(Cl)cc1NC(=O)Cn2cnc3ccccc3c2=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J15 compound treatment 1166252.0 244000.0 1.33 1133336.0 205000.0 1.16 1.7612 0.9975 3627077 CBKinase1_016753 Cc1cccc(c1)c2nnc(SCC(=O)Nc3ccc(Br)cc3F)o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J16 compound treatment 1094554.0 172000.0 0.94 1141892.0 214000.0 1.21 1.5185 0.9925 3627078 CBKinase1_016754 COC(=O)c1ccccc1NC(=O)CSc2nc3cc(Cl)ccc3s2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J17 compound treatment 1009846.0 87700.0 0.48 1032157.0 104000.0 0.59 0.7542 0.9949 3627079 CBKinase1_016755 Cc1sc2ncnc(NCCCN3CCOCC3)c2c1c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J18 compound treatment 979674.0 57600.0 0.31 1032419.0 105000.0 0.59 0.6387 0.9567 3627080 CBKinase1_016756 NC(=O)C1(CCN(CC1)C(=O)CSc2nc3ccccc3o2)N4CCCCC4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J19 compound treatment 992987.0 70900.0 0.39 937056.0 9150.0 0.05 0.3101 0.7943 3627081 CBKinase1_016757 Cc1ccc(C(=O)CC2(O)C(=O)N(CC(=O)N)c3ccccc32)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J20 compound treatment 1027859.0 106000.0 0.58 989191.0 61300.0 0.35 0.6525 0.9698 3627082 CBKinase1_016758 Cc1ccccc1NC(=O)CSc2nnc([nH]2)c3ccncc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J21 mock treatment 939366.0 17200.0 0.09 994786.0 66900.0 0.38 0.3331 0.8574 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J22 mock treatment 861149.0 -61000.0 -0.33 909020.0 -18900.0 -0.11 -0.3106 -0.8889 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J23 compound treatment 807093.0 -115000.0 -0.63 896296.0 -31600.0 -0.18 -0.57 -0.8733 3627083 CBKinase1_016759 Clc1ccc(cc1)n2c(SCC(=O)Nc3ccccc3c4ccccc4)nnc2c5ccncc5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 J24 compound treatment 911007.0 -11100.0 -0.06 879155.0 -48800.0 -0.27 -0.2372 -0.8429 3627084 CBKinase1_016760 COc1ccc(OC)c(NC(=O)CN(C)S(=O)(=O)c2c(C)cc(C)cc2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K01 compound treatment 954551.0 32400.0 0.18 1010117.0 82200.0 0.46 0.4529 0.9129 3627085 CBKinase1_016761 NC(=O)CN1CCN(CCN2C(=O)c3cccc4cccc(C2=O)c34)CC1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K02 compound treatment 942542.0 20400.0 0.11 872459.0 -55400.0 -0.31 -0.1421 -0.4284 3627086 CBKinase1_016762 COC(=O)c1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2c4ccc(C)cc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K03 compound treatment 755538.0 -167000.0 -0.91 944094.0 16200.0 0.09 -0.5786 -0.633 3627087 CBKinase1_016763 COc1ccc(NC(=O)CN(c2ccc(OC)c(Cl)c2)S(=O)(=O)C)cc1Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K04 compound treatment 968323.0 46200.0 0.25 878513.0 -49400.0 -0.28 -0.0185 -0.0492 3627088 CBKinase1_016764 Cc1cccc(Nc2nc(N)nc(CSc3nccc(C)n3)n2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K05 compound treatment 862577.0 -59500.0 -0.33 946420.0 18500.0 0.1 -0.1561 -0.4571 1801167 CBKinase1_016765 CCC(Sc1nc2ccccc2[nH]1)C(=O)Nc3ccc(NC(=O)C)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K06 compound treatment 866554.0 -55600.0 -0.3 912295.0 -15600.0 -0.09 -0.2767 -0.8761 3627089 CBKinase1_016766 Cc1nc(SCC(=O)N)c(C(=O)N)c(C)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K07 mock treatment 909603.0 -12500.0 -0.07 863982.0 -63900.0 -0.36 -0.3031 -0.8265 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K08 mock treatment 898936.0 -23200.0 -0.13 1038548.0 111000.0 0.62 0.3515 0.5523 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K09 compound treatment 1104367.0 182000.0 0.99 953091.0 25200.0 0.14 0.8039 0.7999 3119142 CBKinase1_016767 COc1cc(OC)nc(NC(=O)CS(=O)(=O)c2ccccc2)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K10 compound treatment 993560.0 71400.0 0.39 842841.0 -85100.0 -0.48 -0.0632 -0.1023 3627090 CBKinase1_016768 Brc1ccc(NC(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K11 compound treatment 940452.0 18300.0 0.1 1027724.0 99800.0 0.56 0.4686 0.82 3627091 CBKinase1_016769 OC(COc1ccc(Cl)cc1)Cn2cnc(c2)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K12 compound treatment 990094.0 68000.0 0.37 963669.0 35800.0 0.2 0.405 0.9589 3627092 CBKinase1_016770 CN(CC(=O)Nc1ccc(F)c(Cl)c1)S(=O)(=O)c2c(C)cc(C)cc2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K13 compound treatment 1026045.0 104000.0 0.57 974087.0 46200.0 0.26 0.5853 0.9375 3627093 CBKinase1_016771 COC(=O)c1cccc(NC(=O)CSc2nnc(c3ccc(Cl)cc3)n2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K14 compound treatment 988935.0 66800.0 0.36 848664.0 -79200.0 -0.45 -0.0579 -0.1004 3627094 CBKinase1_016772 CCc1c(C)nc(SCC(=O)Nc2ccc(cc2)C(=O)OC)nc1O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K15 mock treatment 949964.0 27800.0 0.15 964780.0 36900.0 0.21 0.2545 0.9882 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K16 mock treatment 1011965.0 89800.0 0.49 921323.0 -6580.0 -0.04 0.3206 0.6518 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K17 compound treatment 1042188.0 120000.0 0.66 1030412.0 103000.0 0.58 0.8721 0.998 3627095 CBKinase1_016773 COc1cccc(NC(=O)CSc2nc3ccccc3c(=O)n2c4ccc(Br)cc4)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K18 compound treatment 907734.0 -14400.0 -0.08 940019.0 12100.0 0.07 -0.0072 -0.0697 3627096 CBKinase1_016774 Brc1ccc(NC(=O)CSc2nnc([nH]2)c3ccco3)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K19 compound treatment 897101.0 -25000.0 -0.14 888171.0 -39700.0 -0.22 -0.2549 -0.9719 3627097 CBKinase1_016775 Cc1c(C)c(NC(=O)CSc2nnc(c3ccc(Cl)cc3)n2C)ccc1Br 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K20 compound treatment 893976.0 -28100.0 -0.15 880719.0 -47200.0 -0.27 -0.2967 -0.966 3627098 CBKinase1_016776 Cc1nnc(SCc2nc(N)nc(Nc3ccc4ccccc4c3)n2)s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K21 compound treatment 780063.0 -142000.0 -0.78 809514.0 -118000.0 -0.67 -1.0202 -0.9972 3627099 CBKinase1_016777 Cc1ccc(NC(=O)C2Cc3ccccc3CN2S(=O)(=O)c4ccc(C)cc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K22 compound treatment 850700.0 -71400.0 -0.39 910414.0 -17500.0 -0.1 -0.3454 -0.8589 1985920 CBKinase1_016778 C(Oc1nnc(c2ccccc2)c3ccccc13)c4cccnc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K23 mock treatment 878786.0 -43300.0 -0.24 788765.0 -139000.0 -0.78 -0.7218 -0.8812 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 K24 mock treatment 752900.0 -169000.0 -0.92 873715.0 -54200.0 -0.31 -0.8692 -0.8933 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L01 compound treatment 843697.0 -78400.0 -0.43 986607.0 58700.0 0.33 -0.0688 -0.1271 1118768 CBKinase1_016779 CCOC(=O)c1c(C)n(C)c2ccc(OCC(=O)N)cc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L02 compound treatment 885419.0 -36700.0 -0.2 854972.0 -72900.0 -0.41 -0.4324 -0.9454 3627100 CBKinase1_016780 CSc1cccc(NC(=O)CN(C)S(=O)(=O)c2c(C)cc(C)cc2C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L03 compound treatment 890845.0 -31300.0 -0.17 923129.0 -4780.0 -0.03 -0.1398 -0.8086 3627101 CBKinase1_016781 [O-][N+](=O)c1cc(ccc1NCCN2CCOCC2)c3n[nH]c(=O)c4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L04 compound treatment 856647.0 -65500.0 -0.36 876062.0 -51800.0 -0.29 -0.4594 -0.995 3627102 CBKinase1_016782 Cc1cc(C)c2c(O)nc(SCC(=O)c3cccs3)nc2n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L05 compound treatment 857795.0 -64300.0 -0.35 984336.0 56400.0 0.32 -0.0234 -0.0494 3627103 CBKinase1_016783 COc1ccc(Nc2ncnc3n(Cc4ccc(C)cc4)ncc23)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L06 compound treatment 903161.0 -19000.0 -0.1 921225.0 -6680.0 -0.04 -0.0998 -0.9063 3627104 CBKinase1_016784 CC(Sc1nc(=O)cc(N)n1c2ccccc2)C(=O)Nc3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L07 mock treatment 991439.0 69300.0 0.38 1001388.0 73500.0 0.41 0.5605 0.999 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L08 mock treatment 1000967.0 78900.0 0.43 1041222.0 113000.0 0.64 0.756 0.9816 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L09 compound treatment 952973.0 30900.0 0.17 1032660.0 105000.0 0.59 0.5366 0.874 3627105 CBKinase1_016785 Cc1cccc(NC(=O)CSc2nc(O)c3c4CCCCc4sc3n2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L10 compound treatment 1020318.0 98200.0 0.54 944384.0 16500.0 0.09 0.4448 0.8174 3627106 CBKinase1_016786 COCCNS(=O)(=O)c1cc(OC)c(C)cc1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L11 compound treatment 1020516.0 98400.0 0.54 929489.0 1580.0 0.01 0.3862 0.7188 1350816 CBKinase1_016787 CC(C)C(=O)Nc1sc2CCCCc2c1C(=O)Nc3cccnc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L12 compound treatment 1045805.0 124000.0 0.68 1041100.0 113000.0 0.64 0.9286 0.9996 3627107 CBKinase1_016788 O=C(CCS(=O)(=O)c1ccc2ccccc2c1)Nc3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L13 compound treatment 1056293.0 134000.0 0.73 1093177.0 165000.0 0.93 1.1767 0.9929 3627108 CBKinase1_016789 Cc1nnc(SCC(=O)Nc2ccc3ccccc3c2)[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L14 compound treatment 982608.0 60500.0 0.33 1013992.0 86100.0 0.49 0.5766 0.9824 3627109 CBKinase1_016790 Cc1ccc(cc1)S(=O)(=O)N2CCN(CC(O)COc3ccc4ccccc4c3)CC2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L15 mock treatment 991988.0 69900.0 0.38 1641337.0 713000.0 4.02 3.1131 0.7707 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L16 mock treatment 966063.0 43900.0 0.24 1049737.0 122000.0 0.69 0.6552 0.9008 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L17 compound treatment 986314.0 64200.0 0.35 966768.0 38900.0 0.22 0.4027 0.9744 3627110 CBKinase1_016791 CCc1nnc(SCC(=O)Nc2ccccc2Cl)[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L18 compound treatment 992874.0 70800.0 0.39 1053106.0 125000.0 0.71 0.7721 0.9598 3627111 CBKinase1_016792 COc1ccc(cc1OC)S(=O)(=O)N(C)CC(=O)Nc2cccc(c2)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L19 compound treatment 996835.0 74700.0 0.41 955820.0 27900.0 0.16 0.3997 0.9142 3627112 CBKinase1_016793 COc1ccc(cc1CNC(=O)CN2CCOCC2)c3nn(C)c(=O)c4ccccc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L20 compound treatment 907939.0 -14200.0 -0.08 986759.0 58900.0 0.33 0.1798 0.5279 3627113 CBKinase1_016794 CCc1cccc(C)c1NC(=O)CSc2nnc(o2)c3ccc(OC)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L21 compound treatment 949575.0 27500.0 0.15 927147.0 -759.0 0.0 0.103 0.6866 3627114 CBKinase1_016795 CN(CC(=O)Nc1cc(ccc1Cl)C(F)(F)F)S(=O)(=O)c2c(C)cc(C)cc2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L22 compound treatment 828018.0 -94100.0 -0.51 939121.0 11200.0 0.06 -0.3186 -0.6155 3627115 CBKinase1_016796 COc1ccc2[nH]c(SCC(=O)NC3CCCCCC3)nc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L23 mock treatment 822691.0 -99400.0 -0.54 866189.0 -61700.0 -0.35 -0.6298 -0.9769 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 L24 mock treatment 416732.0 -505000.0 -2.76 959396.0 31500.0 0.18 -1.8255 -0.6603 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M01 compound treatment 813887.0 -108000.0 -0.59 1025969.0 98100.0 0.55 -0.027 -0.0333 3627116 CBKinase1_016797 OC1=C(C(N(CCN2CCOCC2)C1=O)c3ccncc3)C(=O)c4cc5ccccc5o4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M02 compound treatment 787542.0 -135000.0 -0.73 921554.0 -6350.0 -0.04 -0.5448 -0.7407 3627117 CBKinase1_016798 C(Sc1nnc(c2ccccc2)n1C3CCCCC3)c4nc5ccccc5[nH]4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M03 compound treatment 817949.0 -104000.0 -0.57 951124.0 23200.0 0.13 -0.3096 -0.5305 3627118 CBKinase1_016799 COCCNS(=O)(=O)c1ccc(Cl)c(Cl)c1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M04 compound treatment 864814.0 -57300.0 -0.31 983131.0 55200.0 0.31 -0.0011 -0.0025 3087985 CBKinase1_016800 COc1ccc(OCc2nc(N)nc(Nc3ccc(C)cc3)n2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M05 compound treatment 852492.0 -69600.0 -0.38 947253.0 19300.0 0.11 -0.1917 -0.4847 1984173 CBKinase1_016801 COc1ccc(cc1OC)C(=O)CSc2nc(O)c3c(C)cc(C)nc3n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M06 compound treatment 894184.0 -27900.0 -0.15 986352.0 58400.0 0.33 0.1251 0.3446 3627119 CBKinase1_016802 CCn1c(SCC(=O)Nc2ccc(Br)c(C)c2C)nnc1c3ccccc3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M07 compound treatment 820342.0 -102000.0 -0.56 982168.0 54300.0 0.31 -0.1766 -0.2785 3627120 CBKinase1_016803 CCOCCCNc1nc2n(C)c(=O)n(C)c(=O)c2[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M08 compound treatment 873156.0 -49000.0 -0.27 906274.0 -21600.0 -0.12 -0.2752 -0.9368 1479397 CBKinase1_016804 NC(=O)c1ccccc1NC(=O)COc2ccc3oc4CCCCc4c3c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M09 mock treatment 901968.0 -20100.0 -0.11 846114.0 -81800.0 -0.46 -0.4038 -0.8519 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M10 mock treatment 869437.0 -52700.0 -0.29 971392.0 43500.0 0.25 -0.0301 -0.0795 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M11 compound treatment 932252.0 10100.0 0.06 946093.0 18200.0 0.1 0.1116 0.9581 3627121 CBKinase1_016805 CCOC(=O)c1ccc(NC(=O)CSc2nc(N)c3c4CCCc4sc3n2)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M12 compound treatment 871176.0 -50900.0 -0.28 993041.0 65100.0 0.37 0.0629 0.1367 3627122 CBKinase1_016806 Ic1ccc(NC(=O)c2ccco2)c(c1)C(=O)NCC3CCCO3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M13 mock treatment 976135.0 54000.0 0.29 997198.0 69300.0 0.39 0.4847 0.9904 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M14 mock treatment 986769.0 64700.0 0.35 1107760.0 180000.0 1.01 0.9664 0.9003 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M15 compound treatment 983275.0 61200.0 0.33 1092626.0 165000.0 0.93 0.8926 0.9047 3627123 CBKinase1_016807 COc1ccc2nc(SCC3=CC(C)(C)N(C(=O)C)c4ccccc34)nc(C)c2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M16 compound treatment 1026334.0 104000.0 0.57 974847.0 46900.0 0.26 0.5894 0.9393 3627124 CBKinase1_016808 CC(=O)Nc1ccc(NC(=O)CSc2nnc(c3ccncc3)n2c4ccc(Cl)cc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M17 compound treatment 998989.0 76900.0 0.42 1079441.0 152000.0 0.85 0.9007 0.9465 3627125 CBKinase1_016809 COc1ccccc1NC(=O)CSc2nnc([nH]2)c3ccncc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M18 compound treatment 940519.0 18400.0 0.1 1008463.0 80600.0 0.45 0.3921 0.8432 3627126 CBKinase1_016810 CCn1c(SCC(=O)Nc2cccc(SC)c2)nnc1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M19 compound treatment 1371690.0 450000.0 2.45 1421487.0 494000.0 2.78 3.7027 0.998 3627127 CBKinase1_016811 Cc1nnc(SCC(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3)s1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M20 compound treatment 1013267.0 91200.0 0.5 998081.0 70200.0 0.4 0.6316 0.9935 3627128 CBKinase1_016812 CCOC(=O)C(Sc1cc(C)nc(N)n1)C(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M21 compound treatment 843432.0 -78700.0 -0.43 996590.0 68700.0 0.39 -0.03 -0.0519 3627129 CBKinase1_016813 Cc1ccc(NC(=O)C2CC(=CCC2C(=O)O)Cl)c(Br)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M22 compound treatment 928387.0 6270.0 0.03 921725.0 -6180.0 -0.03 -4.0E-4 -0.0088 3627130 CBKinase1_016814 Clc1ccc(C(=O)Nc2ccc(I)cc2C(=O)NCc3cccnc3)c(Cl)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M23 compound treatment 914274.0 -7840.0 -0.04 941865.0 14000.0 0.08 0.0254 0.2831 3627131 CBKinase1_016815 CC(C)c1ccc(NC(=O)CSc2nnc(c3ccc(Br)cc3)n2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 M24 compound treatment 882825.0 -39300.0 -0.21 929014.0 1110.0 0.01 -0.1473 -0.6862 3627132 CBKinase1_016816 CCn1c(S)nnc1CNC(=O)c2ccc(OC)c(OC)c2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N01 compound treatment 916524.0 -5590.0 -0.03 968952.0 41000.0 0.23 0.142 0.6085 3627133 CBKinase1_016817 CCn1c(SCC(=O)N)nnc1c2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N02 compound treatment 893416.0 -28700.0 -0.16 982395.0 54500.0 0.31 0.1064 0.3085 2068721 CBKinase1_016818 Cc1oc2nc(SCC(=O)NC3CCCCC3)nc(N)c2c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N03 compound treatment 829696.0 -92400.0 -0.5 1004561.0 76700.0 0.43 -0.0513 -0.0772 3627134 CBKinase1_016819 CCn1c(SCC(=O)Nc2c(C)cc(C)cc2C)nnc1c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N04 compound treatment 921990.0 -127.0 0.0 1035858.0 108000.0 0.61 0.4298 0.7063 1386833 CBKinase1_016820 COc1ccc(Cl)cc1NC(=O)Cn2c(=O)oc3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N05 compound treatment 972509.0 50400.0 0.28 1031143.0 103000.0 0.58 0.606 0.9415 3627135 CBKinase1_016821 Cc1ccc(Cn2ncc3c(ncnc23)N4CCN(CCOc5ccc(C)cc5)CC4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N06 compound treatment 895306.0 -26800.0 -0.15 955113.0 27200.0 0.15 0.0049 0.0233 1985835 CBKinase1_016822 OCCN(CCO)S(=O)(=O)c1cccc2cccnc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N07 compound treatment 972398.0 50300.0 0.27 1059142.0 131000.0 0.74 0.7172 0.9089 3627136 CBKinase1_016823 CCOC(=O)c1c(C)c(C)sc1NC(=O)c2nc3nc(C)cc(C(F)F)n3n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N08 compound treatment 1002951.0 80800.0 0.44 1049548.0 122000.0 0.69 0.7969 0.9773 3627137 CBKinase1_016824 CCCn1c2ccccc2c3nnc(SCCC(=O)O)nc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N09 mock treatment 908881.0 -13200.0 -0.07 1069277.0 141000.0 0.8 0.5123 0.6404 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N10 mock treatment 1035712.0 114000.0 0.62 955433.0 27500.0 0.16 0.5482 0.8576 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N11 compound treatment 873484.0 -48600.0 -0.27 1043707.0 116000.0 0.65 0.2738 0.3885 3627138 CBKinase1_016825 CC(=O)Nc1ccc(cc1)C(=O)CSc2cc(C)c3ccccc3n2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N12 compound treatment 1067005.0 145000.0 0.79 1040239.0 112000.0 0.63 1.007 0.9939 1620088 CBKinase1_016826 CC1=C(C(c2cccnc2)n3nc(SCc4ccccc4)nc3N1)C(=O)Nc5ccccc5C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N13 mock treatment 1041220.0 119000.0 0.65 1051344.0 123000.0 0.7 0.9518 0.9994 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N14 mock treatment 1015830.0 93700.0 0.51 1101007.0 173000.0 0.98 1.0517 0.9546 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N15 compound treatment 1017498.0 95400.0 0.52 851154.0 -76800.0 -0.43 0.0623 0.092 3627139 CBKinase1_016827 CC(O)c1nc2ccccc2n1CCOc3ccccc3C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N16 compound treatment 1034425.0 112000.0 0.61 1152096.0 224000.0 1.26 1.3271 0.9449 3627140 CBKinase1_016828 COC(=O)c1ccccc1NC(=O)CN(C)S(=O)(=O)c2c(C)cc(C)cc2C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N17 compound treatment 998053.0 75900.0 0.41 926268.0 -1640.0 -0.01 0.2866 0.6912 3627141 CBKinase1_016829 COc1ccc(CN(C2CCS(=O)(=O)C2)C(=O)c3oc4ccccc4c3C)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N18 compound treatment 889675.0 -32400.0 -0.18 1118212.0 190000.0 1.07 0.6332 0.5825 1868227 CBKinase1_016830 COc1ccc(OC)c(NC(=O)Cc2coc3ccc4ccccc4c23)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N19 compound treatment 1040383.0 118000.0 0.65 866343.0 -61600.0 -0.35 0.2112 0.2881 1984008 CBKinase1_016831 O=C1CC(Cc2nc(NCCN3CCOCC3)ncc12)c4cccs4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N20 compound treatment 922385.0 268.0 0.0 1038383.0 110000.0 0.62 0.4413 0.7088 3627142 CBKinase1_016832 Cc1cc(C)c(NS(=O)(=O)c2ccc(NC(=O)c3nc4nc(C)cc(C(F)F)n4n3)cc2)c(C)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N21 compound treatment 985835.0 63700.0 0.35 826716.0 -101000.0 -0.57 -0.1573 -0.2355 3627143 CBKinase1_016833 COC(=O)c1ccccc1NC(=O)CSc2nnc(C)[nH]2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N22 compound treatment 1010486.0 88400.0 0.48 1008250.0 80300.0 0.45 0.6614 0.9995 3627144 CBKinase1_016834 COc1ccc(OC)c(NC(=O)CSc2nc(C)cc(=O)[nH]2)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N23 compound treatment 1024602.0 102000.0 0.56 858663.0 -69200.0 -0.39 0.1197 0.1754 1344925 CBKinase1_016835 Cn1ccnc1CN2CCN(Cc3nccn3C)CC2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 N24 compound treatment 1097352.0 175000.0 0.96 1022151.0 94200.0 0.53 1.0521 0.9615 3627145 CBKinase1_016836 CCC(SC1=NCCS1)C(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O01 compound treatment 1037489.0 115000.0 0.63 1032564.0 105000.0 0.59 0.8625 0.9995 3627146 CBKinase1_016837 CN(CC(=O)N1CCC(CC1)C(=O)N)S(=O)(=O)c2ccc(F)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O02 compound treatment 954573.0 32500.0 0.18 955413.0 27500.0 0.16 0.2349 0.9978 1138839 CBKinase1_016838 Clc1ccccc1NC(=O)CSc2nc3cccnc3[nH]2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O03 compound treatment 1042096.0 120000.0 0.66 971814.0 43900.0 0.25 0.6382 0.9114 3627147 CBKinase1_016839 CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3cccc4cccnc34 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O04 compound treatment 1010326.0 88200.0 0.48 1055643.0 128000.0 0.72 0.8496 0.9809 3627148 CBKinase1_016840 CCOc1ccc2[nH]c(SCC(=O)Nc3ccc(C)cc3C)nc2c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O05 compound treatment 1008434.0 86300.0 0.47 1068996.0 141000.0 0.8 0.8955 0.9688 1474445 CBKinase1_016841 OC1(CC(=O)c2ccc3OCCOc3c2)C(=O)N(Cc4ccccc4)c5ccc(Cl)cc51 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O06 compound treatment 990668.0 68600.0 0.37 988355.0 60400.0 0.34 0.5056 0.9989 1876264 CBKinase1_016842 Cc1cccc(c1)n2c(N)cc(=O)nc2SCC(=O)Nc3ccc4ccccc4c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O07 compound treatment 1030170.0 108000.0 0.59 1043445.0 116000.0 0.65 0.8776 0.9988 3627149 CBKinase1_016843 COc1ccc(cc1OC)S(=O)(=O)N(C)CC(=O)Nc2ccc(I)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O08 compound treatment 991258.0 69100.0 0.38 953508.0 25600.0 0.14 0.369 0.913 3627150 CBKinase1_016844 CCn1c(SCC(=O)Nc2cccc(SC)c2)nnc1c3ccccc3Cl 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O09 compound treatment 1042209.0 120000.0 0.66 1015573.0 87700.0 0.49 0.813 0.9903 3627151 CBKinase1_016845 Oc1nc(SCC(=O)Nc2ccccc2Cl)nc3ccccc13 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O10 compound treatment 1041121.0 119000.0 0.65 1069839.0 142000.0 0.8 1.0251 0.9947 3627152 CBKinase1_016846 CC1(C)CC(=O)c2cnc(NC(=O)CSc3nc4ccccc4o3)nc2C1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O11 mock treatment 1032081.0 110000.0 0.6 966199.0 38300.0 0.22 0.5771 0.9046 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O12 mock treatment 981328.0 59200.0 0.32 1048879.0 121000.0 0.68 0.7107 0.9419 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O13 compound treatment 1055203.0 133000.0 0.73 1025587.0 97700.0 0.55 0.9031 0.9906 3627153 CBKinase1_016847 CC(C)c1ccc(NC(=O)CSc2nnc(c3ccccc3Cl)n2C)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O14 compound treatment 1023709.0 102000.0 0.55 1061856.0 134000.0 0.75 0.9261 0.9885 1861017 CBKinase1_016848 COc1ccc(OCC(=O)Nc2sc(C)c(C)c2C(=O)N)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O15 compound treatment 1063294.0 141000.0 0.77 1062640.0 135000.0 0.76 1.082 1.0 3627154 CBKinase1_016849 CC(C)Cc1nnc(SCC(=O)Nc2ccc(C)cc2)[nH]1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O16 compound treatment 991192.0 69100.0 0.38 1043995.0 116000.0 0.65 0.7293 0.9657 3627155 CBKinase1_016850 CC(Sc1cccc2cccc(C(=O)O)c12)C(=O)O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O17 compound treatment 1052684.0 131000.0 0.71 1046116.0 118000.0 0.67 0.9752 0.9994 3627156 CBKinase1_016851 Cc1cc(C)c2c(O)nc(SCC(=O)NCc3ccccc3)nc2n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O18 compound treatment 1000707.0 78600.0 0.43 1019440.0 91500.0 0.52 0.6682 0.9958 3627157 CBKinase1_016852 COc1ccc(CCNC(=O)c2ccc(o2)c3cccc(c3)C(F)(F)F)cc1OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O19 compound treatment 1046427.0 124000.0 0.68 1032016.0 104000.0 0.59 0.8948 0.9974 3627158 CBKinase1_016853 Cc1cc(C(F)F)n2nc(nc2n1)C(=O)Nc3ccc4c(cc(=O)oc4c3)C(F)(F)F 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O20 compound treatment 1039069.0 117000.0 0.64 1028853.0 101000.0 0.57 0.8538 0.9983 3627159 CBKinase1_016854 COc1c(Cl)c(Cl)ccc1S(=O)(=O)n2c(C)nc3ccccc23 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O21 compound treatment 1002849.0 80700.0 0.44 993497.0 65600.0 0.37 0.5731 0.9962 3627160 CBKinase1_016855 Cc1ccc(OCCCn2c(CO)nc3ccccc23)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O22 compound treatment 997876.0 75800.0 0.41 875225.0 -52700.0 -0.3 0.0825 0.162 3627161 CBKinase1_016856 COCCNc1ncnc2n(Cc3ccc(C)cc3)ncc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O23 compound treatment 998021.0 75900.0 0.41 978807.0 50900.0 0.29 0.4959 0.9839 3627162 CBKinase1_016857 O=C(NC1CCS(=O)(=O)C1)c2ccc(cc2)S(=O)(=O)NCC3CCCO3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 O24 compound treatment 1190533.0 268000.0 1.47 941645.0 13700.0 0.08 1.091 0.7434 3627163 CBKinase1_016858 CCn1c(SCC(=O)Nc2cc(Cl)c(Cl)cc2Cl)nnc1c3cccc(C)c3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P01 compound treatment 910940.0 -11200.0 -0.06 882167.0 -45700.0 -0.26 -0.2254 -0.851 3627164 CBKinase1_016859 CCCc1cc(=O)oc2cc(OCC(=O)Nc3ccc4OCCOc4c3)ccc12 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P02 compound treatment 852992.0 -69100.0 -0.38 933957.0 6050.0 0.03 -0.2427 -0.6406 3627165 CBKinase1_016860 CC(Sc1nc(cc(n1)c2ccccc2)c3ccccc3)C(=O)Nc4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P03 compound treatment 904675.0 -17400.0 -0.1 908301.0 -19600.0 -0.11 -0.1455 -0.9973 3627166 CBKinase1_016861 Cc1cccc(N(CC(=O)O)S(=O)(=O)C)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P04 compound treatment 935368.0 13300.0 0.07 930876.0 2970.0 0.02 0.063 0.8483 3627167 CBKinase1_016862 CSc1cccc(NC(=O)CSc2nnc(o2)c3cccc(C)c3)c1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P05 compound treatment 834275.0 -87800.0 -0.48 953489.0 25600.0 0.14 -0.2371 -0.4736 3627168 CBKinase1_016863 CCc1c(O)nc(SC(C)C(=O)Nc2ccc(Cl)cc2)[nH]c1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P06 compound treatment 1012343.0 90200.0 0.49 976659.0 48800.0 0.27 0.5426 0.962 1803439 CBKinase1_016864 CC(Sc1nnc(N)s1)C(=O)Nc2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P07 compound treatment 892854.0 -29300.0 -0.16 957447.0 29500.0 0.17 0.0048 0.0207 3627169 CBKinase1_016865 Cc1ccc(cc1)c2nnc(SCC(=O)Nc3c(C)cc(C)cc3C)o2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P08 compound treatment 771833.0 -150000.0 -0.82 919011.0 -8900.0 -0.05 -0.6156 -0.7489 3627170 CBKinase1_016866 COC(=O)c1cc(NC(=O)CC2Sc3ccccc3NC2=O)cc(c1)C(=O)OC 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P09 compound treatment 973811.0 51700.0 0.28 990858.0 63000.0 0.35 0.4505 0.9936 3627171 CBKinase1_016867 Clc1ccccc1NC(=O)CSc2nnc([nH]2)c3ccccc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P10 compound treatment 980773.0 58700.0 0.32 968637.0 40700.0 0.23 0.3888 0.9867 3627172 CBKinase1_016868 CC(Sc1nc(N)cc(=O)[nH]1)C(=O)Nc2ccc(Cl)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P11 mock treatment 940459.0 18300.0 0.1 979025.0 51100.0 0.29 0.2745 0.9001 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P12 mock treatment 980541.0 58400.0 0.32 983546.0 55600.0 0.31 0.4473 1.0 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P13 compound treatment 938890.0 16800.0 0.09 1161320.0 233000.0 1.32 0.995 0.7545 1801168 CBKinase1_016869 CCC(SC1=NCCS1)C(=O)Nc2ccc(NC(=O)C)cc2 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P14 compound treatment 1009317.0 87200.0 0.48 1081420.0 154000.0 0.87 0.9485 0.9604 3627173 CBKinase1_016870 CC(=O)c1c(C)nn(CC(O)COc2ccc(cc2)C(=O)c3ccc(Cl)cc3)c1C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P15 compound treatment 967913.0 45800.0 0.25 1025697.0 97800.0 0.55 0.5665 0.9361 3627174 CBKinase1_016871 CCn1c(SCC(=O)Nc2cc(C)ccc2OC)nnc1c3ccc(Cl)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P16 compound treatment 954152.0 32000.0 0.17 1035441.0 108000.0 0.61 0.5523 0.8754 3627175 CBKinase1_016872 Cc1cc(C)n(CC(O)COc2ccc(cc2)C(=O)c3ccc(Cl)cc3)n1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P17 compound treatment 1020086.0 98000.0 0.53 1040975.0 113000.0 0.64 0.8288 0.9962 3627176 CBKinase1_016873 CN(C)c1ccc(NC(=O)CSc2nc(c(o2)c3ccccc3)c4ccccc4)cc1 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P18 compound treatment 1004568.0 82500.0 0.45 1047858.0 120000.0 0.68 0.7964 0.9805 3627177 CBKinase1_016874 OC(CNC(=O)CN1C(=O)c2cccc3cccc(C1=O)c23)c4ccccc4 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P19 compound treatment 937858.0 15700.0 0.09 1027538.0 99600.0 0.56 0.4579 0.8059 3627178 CBKinase1_016875 OCCCNC(=O)c1cc2ccccc2oc1=O 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P20 compound treatment 887095.0 -35000.0 -0.19 929874.0 1970.0 0.01 -0.1274 -0.665 3627179 CBKinase1_016876 COc1ccc(cc1NC(=O)C2(CCOCC2)c3ccc(OC)c(OC)c3)[N+](=O)[O-] 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P21 compound treatment 1012203.0 90100.0 0.49 1028984.0 101000.0 0.57 0.7506 0.9973 3627180 CBKinase1_016877 CC1(C)Cc2c(CO1)c(nc3sc4c(O)nnnc4c23)N5CCOCC5 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P22 compound treatment 971729.0 49600.0 0.27 991844.0 63900.0 0.36 0.4464 0.9901 3627181 CBKinase1_016878 CC(N1C(=O)C2C(C3C=CC2C4CC43)C1=O)C(=O)Nc5ccc(cc5)C(=O)C 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P23 compound treatment 966251.0 44100.0 0.24 1009396.0 81500.0 0.46 0.4952 0.9547 3627182 CBKinase1_016879 Clc1ccccc1NC(=O)CSc2nnc(o2)c3ccc(Br)cc3 1010.0027 DAPIStaining(1010.0027) PlasmodiumViabilityAssay 1010.0027.2376 P24 compound treatment 947127.0 25000.0 0.14 937813.0 9910.0 0.06 0.136 0.9221 3627183 CBKinase1_016880 CC(Sc1nc(C)cc(C)n1)C(=O)Nc2ccc(Cl)cc2