ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A01 mock treatment 426991.0 -586000.0 -1.24 446592.0 -531000.0 -1.21 -1.7307 -0.9999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A02 mock treatment 398697.0 -614000.0 -1.3 398123.0 -579000.0 -1.32 -1.8511 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A03 compound treatment 401348.0 -611000.0 -1.3 407322.0 -570000.0 -1.3 -1.8323 -1.0 3001896 Bio2_000321 C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@@]24[C@@H](/C=C/C[C@H](C)C(=O)[C@@](C)(O)/C=C/[C@H]4OC(=O)C)[C@H](O)C1=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A04 mock treatment 578173.0 -434000.0 -0.92 556145.0 -421000.0 -0.96 -1.328 -0.9998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A05 compound treatment 534033.0 -478000.0 -1.01 465038.0 -512000.0 -1.16 -1.5406 -0.9976 236 Bio2_000322 SC(=S)OC1CC2CC1C3CCCC23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A06 mock treatment 582998.0 -429000.0 -0.91 580121.0 -397000.0 -0.9 -1.2822 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A07 compound treatment 772915.0 -240000.0 -0.51 677951.0 -299000.0 -0.68 -0.8402 -0.9896 159 Bio2_000323 COc1c(C=O)c(O)cc2C(=O)c3ccccc3C(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A08 mock treatment 759280.0 -253000.0 -0.54 674524.0 -303000.0 -0.69 -0.8662 -0.9925 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A09 compound treatment 679404.0 -333000.0 -0.71 784795.0 -192000.0 -0.44 -0.8087 -0.9735 2370 Bio2_000324 OCc1ccc(o1)c2nn(Cc3ccccc3)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A10 mock treatment 540967.0 -472000.0 -1.0 692487.0 -285000.0 -0.65 -1.1646 -0.9779 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A11 compound treatment 959380.0 -53100.0 -0.11 826190.0 -151000.0 -0.34 -0.3224 -0.8923 251 Bio2_000325 Nc1ncnc2n(cnc12)C3(CO)OC(=C)C(O)C3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A12 mock treatment 557588.0 -455000.0 -0.96 532790.0 -444000.0 -1.01 -1.3964 -0.9997 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A13 compound treatment 621090.0 -391000.0 -0.83 562550.0 -415000.0 -0.94 -1.2534 -0.998 3001897 Bio2_000326 OC[C@H]1*C[C@@H](O)[C@@H](O)[C@@H]1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A14 mock treatment 606324.0 -406000.0 -0.86 712680.0 -265000.0 -0.6 -1.0341 -0.9846 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A15 compound treatment 591511.0 -421000.0 -0.89 671860.0 -305000.0 -0.69 -1.122 -0.9923 1907766 Bio2_000327 OC[C@H]1*C[C@H](O)[C@@H](O)[C@@H]1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A16 mock treatment 552628.0 -460000.0 -0.97 678290.0 -299000.0 -0.68 -1.1699 -0.9844 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A17 compound treatment 554589.0 -458000.0 -0.97 690196.0 -287000.0 -0.65 -1.1478 -0.9813 3103895 Bio2_000328 C[C@@H]1CC2C3CCC4=CC(=O)C=CC4(C)[C@@]3(F)[C@@H](O)CC2(C)[C@@]1(O)C(=O)CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A18 mock treatment 557749.0 -455000.0 -0.96 703908.0 -273000.0 -0.62 -1.1211 -0.9774 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A19 compound treatment 683549.0 -329000.0 -0.7 655214.0 -322000.0 -0.73 -1.0108 -0.9997 3103896 Bio2_000329 CCCC(=O)Nc1ncnc2n(cnc12)C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3OC(=O)CCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A20 mock treatment 674699.0 -338000.0 -0.72 510939.0 -466000.0 -1.06 -1.256 -0.9818 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A21 compound treatment 641456.0 -371000.0 -0.79 550574.0 -427000.0 -0.97 -1.2421 -0.9946 3001899 Bio2_000330 CCCC(=O)Nc1nc2n(cnc2c(=O)[nH]1)C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3OC(=O)CCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A22 mock treatment 554479.0 -458000.0 -0.97 498908.0 -478000.0 -1.09 -1.4555 -0.9984 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A23 mock treatment 492639.0 -520000.0 -1.1 461679.0 -516000.0 -1.17 -1.6081 -0.9995 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 A24 mock treatment 448319.0 -564000.0 -1.2 430607.0 -547000.0 -1.24 -1.7245 -0.9998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B01 mock treatment 412417.0 -600000.0 -1.27 492353.0 -485000.0 -1.1 -1.679 -0.9975 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B02 mock treatment 825006.0 -187000.0 -0.4 699676.0 -278000.0 -0.63 -0.7272 -0.9752 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B03 compound treatment 1005857.0 -6640.0 -0.01 1096610.0 119000.0 0.27 0.182 0.6695 440 Bio2_000331 COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B04 mock treatment 1047392.0 34900.0 0.07 1015974.0 38800.0 0.09 0.1146 0.9962 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B05 compound treatment 1058029.0 45500.0 0.1 1123258.0 146000.0 0.33 0.303 0.8764 442 Bio2_000332 CCCCCCCCCCCCCCCCCCc1ccc(cc1)C(=O)/C=C/C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B06 mock treatment 1103825.0 91300.0 0.19 1143124.0 166000.0 0.38 0.4036 0.952 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B07 compound treatment 158569.0 -854000.0 -1.81 142208.0 -835000.0 -1.9 -2.6225 -0.9997 3103897 Bio2_000333 C[C@@H](CC(O)[C@H]1OC2CC[C@@]3(CC[C@H](O3)/C=C/[C@@H](C)[C@@H]4CC(=C[C@@]5(O[C@H](C[C@@](C)(O)C(=O)O)CCC5O)O4)C)OC2[C@H](O)C1=C)C6O[C@@]7(CCCCO7)CC[C@H]6C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B08 mock treatment 1019967.0 7470.0 0.02 1164402.0 187000.0 0.43 0.3121 0.7329 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B09 compound treatment 151601.0 -861000.0 -1.83 195364.0 -782000.0 -1.78 -2.5474 -0.9999 3104621 Bio2_000334 CC[C@H]/1CC[C@H]2O[C@@]3(CC[C@@H](C)[C@@H](C[C@H](C)O)O3)[C@H](C)[C@@H](OC(=O)/C=C/[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@](C)(O)[C@H](O)[C@@H](C)C\C=C\C=C1)[C@H]2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B10 mock treatment 1090516.0 78000.0 0.17 1250519.0 273000.0 0.62 0.5563 0.8652 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B11 compound treatment 884706.0 -128000.0 -0.27 723090.0 -254000.0 -0.58 -0.6001 -0.9404 324 Bio2_000335 Cn1cnc2c(NCc3ccccc3)nc(NCCO)nc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B12 mock treatment 1177023.0 165000.0 0.35 1328381.0 351000.0 0.8 0.8112 0.931 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B13 compound treatment 936520.0 -76000.0 -0.16 1032696.0 55500.0 0.13 -0.0247 -0.1207 3103898 Bio2_000336 CC1OC(OC2CC(O)C3(CO)C4[C@H](O)CC5(C)C(CCC5(O)C4CCC3(O)C2)C6=CC(=O)OC6)C(O)C(O)C1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B14 mock treatment 1201686.0 189000.0 0.4 1302791.0 326000.0 0.74 0.807 0.9586 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B15 compound treatment 914284.0 -98200.0 -0.21 1097214.0 120000.0 0.27 0.0457 0.1332 444 Bio2_000337 COC(=O)C1=C(C)NC(=C(C1C)C(=O)OCCSc2ccccc2)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B16 mock treatment 974269.0 -38200.0 -0.08 1204396.0 227000.0 0.52 0.3079 0.589 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B17 compound treatment 1010402.0 -2100.0 0.0 1376283.0 399000.0 0.91 0.6384 0.7036 453 Bio2_000338 COc1cccc(c1N)c2cc(=O)c3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B18 mock treatment 1107633.0 95100.0 0.2 1345267.0 368000.0 0.84 0.7343 0.8531 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B19 compound treatment 1037782.0 25300.0 0.05 934641.0 -42600.0 -0.1 -0.0305 -0.276 1907767 Bio2_000339 CN(C)c1ccc(/C=C/2\C(=O)Nc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B20 mock treatment 1231188.0 219000.0 0.46 1036966.0 59800.0 0.14 0.4239 0.8774 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B21 compound treatment 1034307.0 21800.0 0.05 1148571.0 171000.0 0.39 0.3082 0.7855 387 Bio2_000340 CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CC(C)C)C(C)C)C(C)C)[C@@H](O)CC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B22 mock treatment 1004264.0 -8230.0 -0.02 1122266.0 145000.0 0.33 0.2209 0.6687 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B23 mock treatment 904031.0 -108000.0 -0.23 901591.0 -75600.0 -0.17 -0.2842 -0.9897 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 B24 mock treatment 446150.0 -566000.0 -1.2 528506.0 -449000.0 -1.02 -1.5703 -0.9967 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C01 mock treatment 487297.0 -525000.0 -1.11 569513.0 -408000.0 -0.93 -1.4427 -0.9958 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C02 mock treatment 610460.0 -402000.0 -0.85 715041.0 -262000.0 -0.6 -1.0241 -0.9847 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C03 compound treatment 632180.0 -380000.0 -0.81 664882.0 -312000.0 -0.71 -1.0722 -0.998 1907768 Bio2_000341 [O-][N+](=O)c1ccc(Cl)c(c1)C(=O)Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C04 mock treatment 795504.0 -217000.0 -0.46 855784.0 -121000.0 -0.28 -0.5205 -0.9702 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C05 compound treatment 790538.0 -222000.0 -0.47 772966.0 -204000.0 -0.46 -0.6611 -1.0 1907769 Bio2_000342 *C1CCc2cc(O)c(O)cc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C06 mock treatment 1052412.0 39900.0 0.08 964055.0 -13200.0 -0.03 0.0387 0.4311 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C07 compound treatment 132421.0 -880000.0 -1.87 182699.0 -795000.0 -1.81 -2.5966 -0.9999 2098 Bio2_000343 CC(C)c1cccc(=O)c(O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C08 mock treatment 912685.0 -99800.0 -0.21 892647.0 -84600.0 -0.19 -0.2856 -0.9989 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C09 compound treatment 120012.0 -892000.0 -1.89 166329.0 -811000.0 -1.84 -2.6415 -0.9999 411 Bio2_000344 [I+]1c2ccccc2-c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C10 mock treatment 1081553.0 69100.0 0.15 998481.0 21300.0 0.05 0.1377 0.8932 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C11 compound treatment 129870.0 -883000.0 -1.87 178179.0 -799000.0 -1.82 -2.6076 -0.9999 1961 Bio2_000345 CC(C)(C)c1cc(O)c(cc1O)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C12 mock treatment 1044020.0 31500.0 0.07 1018357.0 41100.0 0.09 0.1134 0.9864 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C13 compound treatment 106852.0 -906000.0 -1.92 131021.0 -846000.0 -1.92 -2.718 -1.0 3103899 Bio2_000346 COc1cccc2C(=O)C3C(C(=C4[C@H](C[C@@](O)(CC4=C3O)C(=O)CO)OC5CC(N)C(O)C(C)O5)O)C(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C14 mock treatment 928645.0 -83900.0 -0.18 1010095.0 32900.0 0.07 -0.0728 -0.3776 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C15 compound treatment 949088.0 -63400.0 -0.13 1025350.0 48100.0 0.11 -0.0177 -0.1019 3000146 Bio2_000347 OC[C@H]1O[C@H](C(O)[C@H]1O)n2cnc3cc(Cl)c(Cl)cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C16 mock treatment 845717.0 -167000.0 -0.35 971037.0 -6170.0 -0.01 -0.2599 -0.7346 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C17 compound treatment 905586.0 -107000.0 -0.23 870017.0 -107000.0 -0.24 -0.3326 -0.9993 3103900 Bio2_000348 OC(=O)c1ccc(cc1)C2=C3C=CC4=[N+]3[Mn+3]5([N+]6=C7C=CC6=C(c8ccc2n85)c9ccc(cc9)C(=O)O)n%10c(=C4c%11ccc(cc%11)C(=O)O)ccc%10=C7c%12ccc(cc%12)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C18 mock treatment 997842.0 -14700.0 -0.03 1082118.0 105000.0 0.24 0.1467 0.6098 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C19 compound treatment 775881.0 -237000.0 -0.5 888937.0 -88300.0 -0.2 -0.4966 -0.9192 3002358 Bio2_000349 COc1cc2CCN(C)[C@@H]3Cc4ccc(OC(=O)c5ccc(cc5)[N+](=O)[O-])c(Oc6ccc(C[C@@H]7N(C)CCc8ccc(Oc(c1OC)c32)cc78)cc6)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C20 mock treatment 1075397.0 62900.0 0.13 961280.0 -15900.0 -0.04 0.0687 0.4971 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C21 compound treatment 280937.0 -732000.0 -1.55 266912.0 -710000.0 -1.61 -2.2385 -0.9998 3002360 Bio2_000350 *[C@H]1O[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCCC(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C22 mock treatment 815175.0 -197000.0 -0.42 869506.0 -108000.0 -0.24 -0.4689 -0.9675 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C23 mock treatment 904566.0 -108000.0 -0.23 1061033.0 83800.0 0.19 -0.027 -0.0908 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 C24 mock treatment 528407.0 -484000.0 -1.03 506660.0 -471000.0 -1.07 -1.4821 -0.9998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D01 mock treatment 418350.0 -594000.0 -1.26 559070.0 -418000.0 -0.95 -1.5629 -0.9904 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D02 mock treatment 926339.0 -86200.0 -0.18 813769.0 -163000.0 -0.37 -0.3919 -0.9465 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D03 compound treatment 1030239.0 17700.0 0.04 870096.0 -107000.0 -0.24 -0.1456 -0.5909 384 Bio2_000351 O=c1[nH]c2ccccc2c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D04 mock treatment 969593.0 -42900.0 -0.09 874473.0 -103000.0 -0.23 -0.2295 -0.9155 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D05 compound treatment 715799.0 -297000.0 -0.63 779116.0 -198000.0 -0.45 -0.7632 -0.9866 290 Bio2_000352 CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)C)CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D06 mock treatment 949765.0 -62700.0 -0.13 1062112.0 84900.0 0.19 0.0425 0.1811 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D07 compound treatment 1028753.0 16300.0 0.03 1053687.0 76500.0 0.17 0.1473 0.8311 455 Bio2_000353 Cc1ccc(cc1)C(=O)Cn2c3CCCCc3sc2=N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D08 mock treatment 1186759.0 174000.0 0.37 1047804.0 70600.0 0.16 0.3747 0.9303 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D09 compound treatment 987101.0 -25400.0 -0.05 1047804.0 70600.0 0.16 0.0754 0.4455 1907770 Bio2_000354 Clc1ccc(cc1)c2nc3sccn3c2/C=N/OCc4ccc(Cl)c(Cl)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D10 mock treatment 1105175.0 92700.0 0.2 1101815.0 125000.0 0.28 0.3392 0.984 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D11 compound treatment 974825.0 -37700.0 -0.08 1057874.0 80700.0 0.18 0.0732 0.366 347 Bio2_000355 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D12 mock treatment 1300309.0 288000.0 0.61 1118509.0 141000.0 0.32 0.6586 0.9551 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D13 compound treatment 1075051.0 62600.0 0.13 1132601.0 155000.0 0.35 0.3436 0.9105 1907771 Bio2_000356 CC1[C@@H]2NC[C@@H](C)C[C@H]2O[C@@]31CC[C@H]4[C@@H]5CC=C6C[C@@H](O)CC[C@]6(C)[C@H]5CC4=C3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D14 mock treatment 971831.0 -40700.0 -0.09 1130311.0 153000.0 0.35 0.1852 0.5164 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D15 compound treatment 921732.0 -90800.0 -0.19 1119807.0 143000.0 0.32 0.0932 0.2472 275745 Bio2_000357 Cc1ccc(cc1)c2nn(c3ncnc(N)c23)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D16 mock treatment 1061203.0 48700.0 0.1 1077390.0 100000.0 0.23 0.2341 0.936 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D17 compound treatment 1059826.0 47300.0 0.1 1548214.0 571000.0 1.3 0.9889 0.7595 349 Bio2_000358 COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D18 mock treatment 931493.0 -81000.0 -0.17 1157874.0 181000.0 0.41 0.169 0.3796 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D19 compound treatment 240240.0 -772000.0 -1.64 252229.0 -725000.0 -1.65 -2.3231 -1.0 244 Bio2_000359 CC[N+](C)(CC)CCC[n+]1c(c2ccccc2)c3cc(N)ccc3c4ccc(N)cc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D20 mock treatment 1046660.0 34200.0 0.07 1019943.0 42700.0 0.1 0.1199 0.9895 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D21 compound treatment 256853.0 -756000.0 -1.6 272409.0 -705000.0 -1.6 -2.2658 -1.0 3002368 Bio2_000360 CC(C)NC[C@H](O)COc1cccc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D22 mock treatment 887799.0 -125000.0 -0.26 933110.0 -44100.0 -0.1 -0.2578 -0.9119 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D23 mock treatment 867988.0 -145000.0 -0.31 763251.0 -214000.0 -0.49 -0.5606 -0.9752 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 D24 mock treatment 562056.0 -450000.0 -0.95 530680.0 -447000.0 -1.02 -1.3931 -0.9995 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E01 mock treatment 481745.0 -531000.0 -1.13 579524.0 -398000.0 -0.9 -1.435 -0.9941 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E02 mock treatment 804524.0 -208000.0 -0.44 834989.0 -142000.0 -0.32 -0.5404 -0.9884 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E03 compound treatment 842531.0 -170000.0 -0.36 815651.0 -162000.0 -0.37 -0.5145 -1.0 413 Bio2_000361 CCCCCC[C@@H]([C@@H](C)O)n1cnc2c(N)ncnc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E04 mock treatment 882580.0 -130000.0 -0.28 803072.0 -174000.0 -0.4 -0.4747 -0.9843 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E05 compound treatment 878930.0 -134000.0 -0.28 834482.0 -143000.0 -0.32 -0.4297 -0.9977 1907772 Bio2_000362 CC(=O)[C@H]1[C@@H](CC2C3CC=C4C[C@@H](O)CCC4(C)C3CCC12C)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E06 mock treatment 889437.0 -123000.0 -0.26 934946.0 -42300.0 -0.1 -0.2524 -0.9079 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E07 compound treatment 1050276.0 37800.0 0.08 963017.0 -14200.0 -0.03 0.0338 0.3916 386 Bio2_000363 C[C@@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]2CC[C@@H]1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E08 mock treatment 903866.0 -109000.0 -0.23 907373.0 -69800.0 -0.16 -0.2751 -0.9835 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E09 compound treatment 808636.0 -204000.0 -0.43 804093.0 -173000.0 -0.39 -0.5839 -0.9989 2080384 Bio2_000364 COc1cc(cc(OC)c1O)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](OC4OC5COC(C)OC5C(O)C4O)c6cc7OCOc7cc26 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E10 mock treatment 1118785.0 106000.0 0.23 1073196.0 96000.0 0.22 0.3136 0.9999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E11 compound treatment 140603.0 -872000.0 -1.85 160567.0 -817000.0 -1.86 -2.6199 -1.0 415 Bio2_000365 FC(F)(F)Oc1ccc(NN=C(C#N)C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E12 mock treatment 1166824.0 154000.0 0.33 1005473.0 28300.0 0.06 0.2768 0.8301 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E13 compound treatment 1003697.0 -8800.0 -0.02 1101111.0 124000.0 0.28 0.186 0.6588 3002452 Bio2_000366 CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E14 mock treatment 1105871.0 93400.0 0.2 1171600.0 194000.0 0.44 0.4525 0.9344 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E15 compound treatment 134223.0 -878000.0 -1.86 146145.0 -831000.0 -1.89 -2.6526 -1.0 3104393 Bio2_000367 CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)/C(=C/C=C\[C@H](OC)[C@@H](OC(=O)N)/C(=C/[C@H](C)[C@H]1O)/C)/C)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E16 mock treatment 1050002.0 37500.0 0.08 1073496.0 96300.0 0.22 0.211 0.906 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E17 compound treatment 959334.0 -53200.0 -0.11 924497.0 -52700.0 -0.12 -0.1644 -0.9995 3103903 Bio2_000368 Cc1ccc(cc1)C2=CCc3cc(C)cc(C)c3C2=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E18 mock treatment 1106416.0 93900.0 0.2 980442.0 3230.0 0.01 0.146 0.7327 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E19 compound treatment 226625.0 -786000.0 -1.67 212189.0 -765000.0 -1.74 -2.4079 -0.9998 576 Bio2_000369 Cn1cc(C2=C(C(=O)NC2=O)c3cn(CCCSC(=N)N)c4ccccc34)c5ccccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E20 mock treatment 998877.0 -13600.0 -0.03 909419.0 -67800.0 -0.15 -0.1294 -0.8252 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E21 compound treatment 489321.0 -523000.0 -1.11 446137.0 -531000.0 -1.21 -1.638 -0.9991 162 Bio2_000370 CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E22 mock treatment 1002669.0 -9830.0 -0.02 1066957.0 89700.0 0.2 0.1295 0.6316 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E23 mock treatment 937704.0 -74800.0 -0.16 1028785.0 51600.0 0.12 -0.0292 -0.1481 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 E24 mock treatment 504930.0 -508000.0 -1.08 519108.0 -458000.0 -1.04 -1.4973 -0.9999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F01 mock treatment 518508.0 -494000.0 -1.05 757401.0 -220000.0 -0.5 -1.0939 -0.9427 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F02 mock treatment 661237.0 -351000.0 -0.74 906075.0 -71100.0 -0.16 -0.6409 -0.8411 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F03 compound treatment 126247.0 -886000.0 -1.88 177367.0 -800000.0 -1.82 -2.6144 -0.9999 3002455 Bio2_000371 *[C@H]1O[C@H]([C@H](O)[C@@H]1NC(=O)C(N)Cc2ccccc2)n3cnc4c(ncnc34)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F04 mock treatment 1168026.0 156000.0 0.33 1029967.0 52800.0 0.12 0.318 0.9062 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F05 compound treatment 1089075.0 76600.0 0.16 1536795.0 560000.0 1.27 1.0144 0.7909 1907773 Bio2_000372 NC(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccc4OCOc4c3)c5ccccn5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F06 mock treatment 915086.0 -97400.0 -0.21 1094611.0 117000.0 0.27 0.0427 0.1266 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F07 compound treatment 1089196.0 76700.0 0.16 1002333.0 25100.0 0.06 0.1554 0.9015 1000035 Bio2_000373 O=C1c2ccccc2-c3n[nH]c4cccc1c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F08 mock treatment 1051503.0 39000.0 0.08 1183722.0 207000.0 0.47 0.3905 0.819 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F09 compound treatment 1113795.0 101000.0 0.21 937908.0 -39300.0 -0.09 0.0887 0.3812 353 Bio2_000374 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F10 mock treatment 1277414.0 265000.0 0.56 1198825.0 222000.0 0.5 0.7534 0.9985 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F11 compound treatment 141724.0 -871000.0 -1.85 164582.0 -813000.0 -1.85 -2.6117 -1.0 3104890 Bio2_000375 CO[C@@H]1CC(CC(C)[C@@H]2CC(=O)[C@H](C)/C=C(\C)/[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)/C=C/C=C/C=C(\C)/[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)OC)CC[C@H]1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F12 mock treatment 1472139.0 460000.0 0.97 1619639.0 642000.0 1.46 1.7218 0.9806 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F13 compound treatment 1147402.0 135000.0 0.29 1330629.0 353000.0 0.8 0.7704 0.9033 1907774 Bio2_000376 CC(C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F14 mock treatment 1232154.0 220000.0 0.47 1253402.0 276000.0 0.63 0.7733 0.9892 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F15 compound treatment 1086575.0 74100.0 0.16 1195335.0 218000.0 0.5 0.4617 0.8876 285 Bio2_000377 O=C(NCCCCCCNC(=O)ON=C1CCCCC1)ON=C2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F16 mock treatment 1116033.0 104000.0 0.22 1258106.0 281000.0 0.64 0.6068 0.8985 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F17 compound treatment 1070016.0 57500.0 0.12 1103066.0 126000.0 0.29 0.2886 0.9277 151 Bio2_000378 CCCCCCCCCCCCCCCC(=O)C1=C(O)C(CO)OC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F18 mock treatment 1107260.0 94800.0 0.2 1110643.0 133000.0 0.3 0.3566 0.98 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F19 compound treatment 373027.0 -639000.0 -1.36 313018.0 -664000.0 -1.51 -2.0264 -0.9986 291 Bio2_000379 CC[C@H](CO)Nc1nc(NCc2ccccc2)c3ncn(C(C)C)c3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F20 mock treatment 1073820.0 61300.0 0.13 1011356.0 34100.0 0.08 0.1468 0.9696 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F21 compound treatment 789909.0 -223000.0 -0.47 810620.0 -167000.0 -0.38 -0.6015 -0.9941 320 Bio2_000380 CC(=O)c1c(O)c(C)c(O)c(Cc2c(O)c(C(=O)/C=C/c3ccccc3)c4OC(C)(C)C=Cc4c2O)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F22 mock treatment 994631.0 -17900.0 -0.04 967356.0 -9850.0 -0.02 -0.0426 -0.9686 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F23 mock treatment 962997.0 -49500.0 -0.1 1033166.0 56000.0 0.13 0.0158 0.0955 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 F24 mock treatment 569494.0 -443000.0 -0.94 508348.0 -469000.0 -1.07 -1.4178 -0.998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G01 mock treatment 779612.0 -233000.0 -0.49 666566.0 -311000.0 -0.71 -0.8485 -0.9847 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G02 mock treatment 868545.0 -144000.0 -0.31 814518.0 -163000.0 -0.37 -0.4773 -0.9954 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G03 compound treatment 143656.0 -869000.0 -1.84 194274.0 -783000.0 -1.78 -2.5611 -0.9999 152 Bio2_000381 Cn1c2ccccc2c3c4C(=O)NCc4c5c6ccccc6n(CCC#N)c5c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G04 mock treatment 911669.0 -101000.0 -0.21 895843.0 -81400.0 -0.18 -0.282 -0.9974 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G05 compound treatment 952726.0 -59800.0 -0.13 915834.0 -61400.0 -0.14 -0.1883 -0.9988 1298 Bio2_000382 CS(=O)(=O)Nc1ccc(cc1Oc2ccccc2)[N+](=O)[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G06 mock treatment 1363312.0 351000.0 0.74 966850.0 -10400.0 -0.02 0.5092 0.6844 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G07 compound treatment 959011.0 -53500.0 -0.11 977305.0 96.3 0.0 -0.08 -0.7057 414 Bio2_000383 CC1CNCCN1S(=O)(=O)c2cccc3cnccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G08 mock treatment 1292207.0 280000.0 0.59 1038264.0 61100.0 0.14 0.5174 0.8497 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G09 compound treatment 1132723.0 120000.0 0.25 1305782.0 329000.0 0.75 0.7084 0.8976 607 Bio2_000384 Brc1ccc(/C=C/CNCCNS(=O)(=O)c2cccc3cnccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G10 mock treatment 1242972.0 230000.0 0.49 1255302.0 278000.0 0.63 0.7926 0.9919 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G11 compound treatment 1079039.0 66500.0 0.14 1071269.0 94100.0 0.21 0.251 0.9796 3002468 Bio2_000385 NCCNOc1cccc2cnccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G12 mock treatment 1317163.0 305000.0 0.65 1439388.0 462000.0 1.05 1.1997 0.9727 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G13 compound treatment 983839.0 -28700.0 -0.06 1401251.0 424000.0 0.96 0.6387 0.6612 610 Bio2_000386 O=S(=O)(N1CCCNCC1)c2cccc3cnccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G14 mock treatment 965772.0 -46700.0 -0.1 1214856.0 238000.0 0.54 0.312 0.568 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G15 compound treatment 1171008.0 159000.0 0.34 945585.0 -31600.0 -0.07 0.1868 0.5435 609 Bio2_000387 NC(=N)NCCNS(=O)(=O)c1cccc2cnccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G16 mock treatment 1309144.0 297000.0 0.63 1093179.0 116000.0 0.26 0.6311 0.9255 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G17 compound treatment 1129350.0 117000.0 0.25 928057.0 -49200.0 -0.11 0.0961 0.3538 611 Bio2_000388 COCc1cc(O)c(O)c(O)c1c2c(O)c(O)c(O)cc2COC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G18 mock treatment 1186131.0 174000.0 0.37 1061320.0 84100.0 0.19 0.3955 0.9535 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G19 compound treatment 1320506.0 308000.0 0.65 1199840.0 223000.0 0.51 0.8196 0.9921 465 Bio2_000389 NCCc1c[nH]cn1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G20 mock treatment 1132760.0 120000.0 0.25 1191127.0 214000.0 0.49 0.5242 0.9546 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G21 compound treatment 1153029.0 141000.0 0.3 1055741.0 78500.0 0.18 0.3369 0.97 239 Bio2_000390 CC(=O)OCOC(c1ccc2ccccc2c1)P(=O)(OCOC(=O)C)OCOC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G22 mock treatment 1146897.0 134000.0 0.28 1107054.0 130000.0 0.3 0.4102 0.9998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G23 mock treatment 998844.0 -13700.0 -0.03 1041738.0 64500.0 0.15 0.0833 0.5569 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 G24 mock treatment 622706.0 -390000.0 -0.83 733231.0 -244000.0 -0.55 -0.9765 -0.9812 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H01 mock treatment 724597.0 -288000.0 -0.61 703135.0 -274000.0 -0.62 -0.8722 -0.9999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H02 mock treatment 1180534.0 168000.0 0.36 1039806.0 62600.0 0.14 0.3525 0.919 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H03 compound treatment 1130996.0 118000.0 0.25 1369602.0 392000.0 0.89 0.8085 0.8723 3104891 Bio2_000391 CC(=O)OCOC(P(=O)OCOC(=O)C)c1cc(ccc1Oc2ccc(Br)cc2)[N+](=O)[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H04 mock treatment 1257420.0 245000.0 0.52 1145958.0 169000.0 0.38 0.6384 0.9889 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H05 compound treatment 1046086.0 33600.0 0.07 940011.0 -37200.0 -0.08 -0.0095 -0.0855 1907775 Bio2_000392 CS(=O)(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H06 mock treatment 1096068.0 83600.0 0.18 1225801.0 249000.0 0.57 0.5249 0.8862 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H07 compound treatment 948980.0 -63500.0 -0.13 949919.0 -27300.0 -0.06 -0.1391 -0.9381 457 Bio2_000393 Oc1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H08 mock treatment 1311090.0 299000.0 0.63 1548295.0 571000.0 1.3 1.3657 0.9455 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H09 compound treatment 124685.0 -888000.0 -1.88 134867.0 -842000.0 -1.92 -2.685 -1.0 1000586 Bio2_000394 O/N=C\1/C(=C\2/C(=O)Nc3ccccc23)/Nc4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H10 mock treatment 1525097.0 513000.0 1.09 1571791.0 595000.0 1.35 1.7243 0.9941 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H11 compound treatment 1543185.0 531000.0 1.13 1634288.0 657000.0 1.49 1.8519 0.9902 3104892 Bio2_000395 O=C/1Nc2ccccc2\C1=C/3\Nc4ccccc4C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H12 mock treatment 1587755.0 575000.0 1.22 1733647.0 756000.0 1.72 2.0784 0.9858 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H13 compound treatment 1489885.0 477000.0 1.01 1562157.0 585000.0 1.33 1.656 0.9909 429 Bio2_000396 NCCc1c[nH]c2ccc(O)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H14 mock treatment 1446765.0 434000.0 0.92 1265207.0 288000.0 0.65 1.114 0.9861 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H15 compound treatment 1476294.0 464000.0 0.98 1235841.0 259000.0 0.59 1.111 0.9698 2269 Bio2_000397 Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H16 mock treatment 1473503.0 461000.0 0.98 1175791.0 199000.0 0.45 1.0103 0.9385 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H17 compound treatment 1560821.0 548000.0 1.16 1324983.0 348000.0 0.79 1.3811 0.9824 2301 Bio2_000398 O=C1CCc2c(O1)ccc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H18 mock treatment 1746788.0 734000.0 1.56 1331407.0 354000.0 0.81 1.6702 0.9529 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H19 compound treatment 1356017.0 344000.0 0.73 1013060.0 35900.0 0.08 0.5726 0.7814 650 Bio2_000399 CC(C)(C)n1nc(c2ccc(Cl)cc2)c3c(N)ncnc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H20 mock treatment 1304398.0 292000.0 0.62 918835.0 -58400.0 -0.13 0.3437 0.5431 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H21 compound treatment 930054.0 -82400.0 -0.17 796685.0 -181000.0 -0.41 -0.4138 -0.9276 648 Bio2_000400 Oc1cc(O)cc(/C=C/c2ccc(O)c(O)c2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H22 mock treatment 1119110.0 107000.0 0.23 935982.0 -41200.0 -0.09 0.0935 0.3823 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H23 mock treatment 1085330.0 72800.0 0.15 957604.0 -19600.0 -0.04 0.0777 0.4832 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 H24 mock treatment 832806.0 -180000.0 -0.38 704494.0 -273000.0 -0.62 -0.7078 -0.9726 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I01 mock treatment 1059372.0 46900.0 0.1 978374.0 1170.0 0.0 0.0721 0.7257 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I02 mock treatment 1068149.0 55700.0 0.12 1023917.0 46700.0 0.11 0.1585 0.9986 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I03 compound treatment 1256832.0 244000.0 0.52 1553929.0 577000.0 1.31 1.2934 0.9175 369 Bio2_000401 CCOc1ccc(cc1)c2nc3cc(ccc3[nH]2)c4nc5cc(ccc5[nH]4)N6CCN(C)CC6 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I04 mock treatment 1090361.0 77900.0 0.17 960059.0 -17100.0 -0.04 0.0891 0.5256 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I05 compound treatment 1122502.0 110000.0 0.23 945269.0 -31900.0 -0.07 0.1136 0.4649 1001953 Bio2_000402 C/C=C/1\C2Cc3[nH]c(=O)ccc3C1(N)CC(=C2)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I06 mock treatment 1398085.0 386000.0 0.82 991147.0 13900.0 0.03 0.6004 0.734 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I07 compound treatment 1636818.0 624000.0 1.32 1158955.0 182000.0 0.41 1.2281 0.8857 1907776 Bio2_000403 CC(C)[C@H](O)CCC(C)C1CCC2C3CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I08 mock treatment 1626857.0 614000.0 1.3 1107867.0 131000.0 0.3 1.131 0.8466 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I09 compound treatment 1662415.0 650000.0 1.38 1168703.0 191000.0 0.44 1.2821 0.8873 3002553 Bio2_000404 C[C@@H]([C@@H](C)N1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I10 mock treatment 1439760.0 427000.0 0.91 1148035.0 171000.0 0.39 0.9151 0.9285 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I11 compound treatment 1274568.0 262000.0 0.56 1095236.0 118000.0 0.27 0.5826 0.9443 2797 Bio2_000405 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)O)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I12 mock treatment 1693747.0 681000.0 1.44 1342799.0 366000.0 0.83 1.609 0.9656 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I13 compound treatment 218054.0 -794000.0 -1.68 211097.0 -766000.0 -1.74 -2.4225 -0.9999 3002555 Bio2_000406 *CC[C@@H](C)C[C@H](C)C[C@H](C)C(=O)/C=C(\O)/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)C[C@@H]1CC[C@](C)(O1)[C@H]2CC[C@](C)(O2)[C@@H](C)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I14 mock treatment 1971358.0 959000.0 2.03 1185988.0 209000.0 0.47 1.773 0.8494 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I15 compound treatment 1838868.0 826000.0 1.75 1200455.0 223000.0 0.51 1.5977 0.876 1505 Bio2_000407 CC(C)Cn1c(=O)n(C)c(=O)c2[nH]cnc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I16 mock treatment 1398882.0 386000.0 0.82 1042764.0 65600.0 0.15 0.6846 0.8223 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I17 compound treatment 1585393.0 573000.0 1.21 1148901.0 172000.0 0.39 1.1348 0.8896 1054783 Bio2_000408 OCCSC1=C(SCCO)C(=O)c2ccccc2C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I18 mock treatment 1802587.0 790000.0 1.67 1171590.0 194000.0 0.44 1.4969 0.8641 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I19 compound treatment 1397004.0 385000.0 0.82 1136865.0 160000.0 0.36 0.8331 0.9336 422 Bio2_000409 Oc1cccc2C(=O)C=CC(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I20 mock treatment 1339953.0 327000.0 0.69 1252187.0 275000.0 0.63 0.9329 0.9986 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I21 compound treatment 912049.0 -100000.0 -0.21 662998.0 -314000.0 -0.71 -0.6557 -0.8796 1907777 Bio2_000410 COC(=O)[C@@]1(O)C[C@@H]2O[C@@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I22 mock treatment 1259322.0 247000.0 0.52 1197596.0 220000.0 0.5 0.7243 0.9998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I23 mock treatment 1302383.0 290000.0 0.61 1147439.0 170000.0 0.39 0.7082 0.9752 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 I24 mock treatment 847887.0 -165000.0 -0.35 801526.0 -176000.0 -0.4 -0.5292 -0.9977 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J01 mock treatment 741701.0 -271000.0 -0.57 660647.0 -317000.0 -0.72 -0.9149 -0.9937 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J02 mock treatment 1026292.0 13800.0 0.03 1089672.0 112000.0 0.26 0.2015 0.7829 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J03 compound treatment 1094982.0 82500.0 0.17 1058513.0 81300.0 0.18 0.2544 0.9996 837968 Bio2_000411 Nc1ncnc2n(cnc12)C3CCCO3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J04 mock treatment 1109655.0 97200.0 0.21 1192827.0 216000.0 0.49 0.4923 0.9258 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J05 compound treatment 1008459.0 -4040.0 -0.01 1158365.0 181000.0 0.41 0.2852 0.6923 790507 Bio2_000412 OC(=O)CN1C(=O)c2cccc3cccc(C1=O)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J06 mock treatment 1435300.0 423000.0 0.9 1188044.0 211000.0 0.48 0.9727 0.957 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J07 compound treatment 142746.0 -870000.0 -1.84 104184.0 -873000.0 -1.98 -2.7073 -0.9993 3104896 Bio2_000413 CN[C@@H]1C[C@@]2(C)O[C@@H]([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J08 mock treatment 1317062.0 305000.0 0.65 1293409.0 316000.0 0.72 0.9649 0.9986 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J09 compound treatment 1447474.0 435000.0 0.92 1219086.0 242000.0 0.55 1.0409 0.9695 197 Bio2_000414 O[C@@H]1CN2CCC[C@@H](O)[C@@H]2[C@@H]1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J10 mock treatment 1409365.0 397000.0 0.84 1393190.0 416000.0 0.95 1.2637 0.9983 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J11 compound treatment 1380720.0 368000.0 0.78 1250081.0 273000.0 0.62 0.9907 0.9935 368 Bio2_000415 CC/C(=C(\c1ccccc1)/c2ccc(OCCN(C)C)cc2)/c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J12 mock treatment 1379495.0 367000.0 0.78 1246681.0 269000.0 0.61 0.9834 0.993 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J13 compound treatment 194438.0 -818000.0 -1.73 184276.0 -793000.0 -1.8 -2.5011 -0.9998 1000045 Bio2_000416 CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c3ccccc3)C4[C@@]5(CO[C@@H]5C[C@H](O)[C@@]4(C)C1=O)OC(=O)C)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c6ccccc6)c7ccccc7 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J14 mock treatment 1351895.0 339000.0 0.72 1338049.0 361000.0 0.82 1.0889 0.9979 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J15 compound treatment 1455986.0 443000.0 0.94 1241980.0 265000.0 0.6 1.0905 0.9768 658 Bio2_000417 Clc1cc(Cl)cc(/C=C(\C#N)/c2cccnc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J16 mock treatment 1537514.0 525000.0 1.11 1582199.0 605000.0 1.38 1.7596 0.9945 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J17 compound treatment 1799389.0 787000.0 1.67 1436680.0 459000.0 1.04 1.9182 0.9746 370 Bio2_000418 O=C1N(C2CCC(=O)NC2=O)C(=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J18 mock treatment 1599629.0 587000.0 1.24 1286051.0 309000.0 0.7 1.3766 0.9633 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J19 compound treatment 1307751.0 295000.0 0.63 1132906.0 156000.0 0.35 0.6929 0.9636 358 Bio2_000419 N[C@@H](CCCNC(=S)N)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J20 mock treatment 1314715.0 302000.0 0.64 1041208.0 64000.0 0.15 0.5559 0.8461 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J21 compound treatment 186320.0 -826000.0 -1.75 177512.0 -800000.0 -1.82 -2.5241 -0.9998 572 Bio2_000420 CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c3c[nH]c4ccccc34)c5ccccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J22 mock treatment 990421.0 -22100.0 -0.05 955757.0 -21500.0 -0.05 -0.0676 -0.9998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J23 mock treatment 1018193.0 5700.0 0.01 1082751.0 106000.0 0.24 0.1782 0.7417 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 J24 mock treatment 692896.0 -320000.0 -0.68 837306.0 -140000.0 -0.32 -0.704 -0.9406 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K01 mock treatment 652115.0 -360000.0 -0.76 637944.0 -339000.0 -0.77 -1.0856 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K02 mock treatment 870961.0 -142000.0 -0.3 852065.0 -125000.0 -0.28 -0.4134 -0.9996 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K03 compound treatment 134575.0 -878000.0 -1.86 148297.0 -829000.0 -1.88 -2.6486 -1.0 3419827 Bio2_000421 CN(C(Cc1ccc(OS(=O)(=O)c2cccc3cnccc23)cc1)C(=O)N4CCN(CC4)c5ccccc5)S(=O)(=O)c6cccc7cnccc67 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K04 mock treatment 986477.0 -26000.0 -0.06 927764.0 -49400.0 -0.11 -0.1185 -0.9463 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K05 compound treatment 856487.0 -156000.0 -0.33 853462.0 -124000.0 -0.28 -0.4328 -0.9968 1907778 Bio2_000422 *[C@@]1(O)C[C@@H]2O[C@@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K06 mock treatment 1027328.0 14800.0 0.03 883051.0 -94200.0 -0.21 -0.1291 -0.5969 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K07 compound treatment 796842.0 -216000.0 -0.46 627469.0 -350000.0 -0.8 -0.8855 -0.9655 3104897 Bio2_000423 CCC(C)[C@@H](CO[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCS(=O)(=O)C)C(=O)OC(C)C)NC[C@@H](N)CS 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K08 mock treatment 1151302.0 139000.0 0.29 953527.0 -23700.0 -0.05 0.17 0.5683 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K09 compound treatment 316315.0 -696000.0 -1.48 322231.0 -655000.0 -1.49 -2.0966 -1.0 1908 Bio2_000424 [O-][n+]1onc(c1C#N)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K10 mock treatment 1601064.0 589000.0 1.25 1056133.0 78900.0 0.18 1.0092 0.8006 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K11 compound treatment 1269445.0 257000.0 0.54 1256190.0 279000.0 0.63 0.8337 0.9971 3001166 Bio2_000425 C[C@H]/1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]3CSC(=O)N3)OC(=O)\C=C(\C)/CC/C=C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K12 mock treatment 1317234.0 305000.0 0.65 1214482.0 237000.0 0.54 0.8383 0.996 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K13 compound treatment 1161964.0 149000.0 0.32 1163460.0 186000.0 0.42 0.5235 0.9898 284 Bio2_000426 OC(=O)c1cc(ccc1O)N(Cc2ccccc2O)Cc3cc(O)ccc3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K14 mock treatment 1269247.0 257000.0 0.54 948329.0 -28900.0 -0.07 0.3384 0.6173 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K15 compound treatment 629408.0 -383000.0 -0.81 625856.0 -351000.0 -0.8 -1.1391 -1.0 1907779 Bio2_000427 CC(C)n1cnc2c(NCc3ccccc3)nc(NCCO)nc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K16 mock treatment 1338812.0 326000.0 0.69 1034768.0 57600.0 0.13 0.5817 0.8262 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K17 compound treatment 999582.0 -12900.0 -0.03 1000876.0 23700.0 0.05 0.0187 0.3095 3104898 Bio2_000428 CC(C)C[C@H](NC(=O)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K18 mock treatment 1537681.0 525000.0 1.11 1065373.0 88200.0 0.2 0.929 0.8212 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K19 compound treatment 1124616.0 112000.0 0.24 878955.0 -98300.0 -0.22 0.0101 0.031 1954 Bio2_000429 Cc1ccc(cc1)S(=O)(=O)/C=C/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K20 mock treatment 1045384.0 32900.0 0.07 909072.0 -68100.0 -0.15 -0.0602 -0.3546 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K21 compound treatment 689951.0 -323000.0 -0.68 649867.0 -327000.0 -0.74 -1.0098 -0.9991 1002387 Bio2_000430 Oc1ccc(C=C(C#N)C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K22 mock treatment 921933.0 -90600.0 -0.19 883052.0 -94200.0 -0.21 -0.2871 -0.9985 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K23 mock treatment 728584.0 -284000.0 -0.6 755379.0 -222000.0 -0.5 -0.7822 -0.9961 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 K24 mock treatment 573443.0 -439000.0 -0.93 522064.0 -455000.0 -1.03 -1.3899 -0.9986 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L01 mock treatment 500275.0 -512000.0 -1.09 611383.0 -366000.0 -0.83 -1.356 -0.9913 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L02 mock treatment 1086484.0 74000.0 0.16 958137.0 -19100.0 -0.04 0.0802 0.4931 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L03 compound treatment 1027244.0 14700.0 0.03 902310.0 -74900.0 -0.17 -0.0983 -0.5678 566 Bio2_000431 COc1cc(/C=C(\C#N)/C(=O)N)cc(CSc2nc3ccccc3s2)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L04 mock treatment 893640.0 -119000.0 -0.25 992227.0 15000.0 0.03 -0.154 -0.6058 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L05 compound treatment 870497.0 -142000.0 -0.3 971977.0 -5230.0 -0.01 -0.2213 -0.7345 1907780 Bio2_000432 COC1=CC(=O)OC(C1)/C=C/c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L06 mock treatment 1059025.0 46500.0 0.1 987748.0 10500.0 0.02 0.0867 0.854 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L07 compound treatment 146659.0 -866000.0 -1.84 128208.0 -849000.0 -1.93 -2.6628 -0.9997 431 Bio2_000433 C(CN(Cc1ccccn1)Cc2ccccn2)N(Cc3ccccn3)Cc4ccccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L08 mock treatment 1067485.0 55000.0 0.12 1100050.0 123000.0 0.28 0.2799 0.9249 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L09 compound treatment 177686.0 -835000.0 -1.77 135191.0 -842000.0 -1.91 -2.6051 -0.9992 199 Bio2_000434 C[C@H](/C=C(\C)/C=C/C(=O)NO)C(=O)c1ccc(cc1)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L10 mock treatment 1542113.0 530000.0 1.12 1030892.0 53700.0 0.12 0.8802 0.7794 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L11 compound treatment 503315.0 -509000.0 -1.08 489160.0 -488000.0 -1.11 -1.5479 -0.9999 437 Bio2_000435 CN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L12 mock treatment 1239429.0 227000.0 0.48 1240642.0 263000.0 0.6 0.7637 0.9941 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L13 compound treatment 612056.0 -400000.0 -0.85 664822.0 -312000.0 -0.71 -1.1025 -0.9961 3001422 Bio2_000436 *C1OC(OC2OC(CC(O)C3OC(C(O)C3O)n4ccc(=O)[nH]c4=O)C(O)C(O)C2NC(=O)/C=C\*C(C)C)C(NC(=O)C)C(O)C1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L14 mock treatment 1089496.0 77000.0 0.16 1152805.0 176000.0 0.4 0.3977 0.9221 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L15 compound treatment 997143.0 -15400.0 -0.03 1001205.0 24000.0 0.05 0.0156 0.2449 203 Bio2_000437 NC(=C(C#N)C#N)/C(=C/c1ccc2[nH]ccc2c1)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L16 mock treatment 1059870.0 47400.0 0.1 1056753.0 79500.0 0.18 0.1989 0.9615 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L17 compound treatment 1081236.0 68700.0 0.15 961947.0 -15300.0 -0.03 0.0785 0.5241 553 Bio2_000438 Oc1cc(C=C(C#N)C#N)ccc1[N+](=O)[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L18 mock treatment 1073097.0 60600.0 0.13 1082726.0 106000.0 0.24 0.2605 0.9572 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L19 compound treatment 904754.0 -108000.0 -0.23 1083706.0 106000.0 0.24 0.0097 0.0291 568 Bio2_000439 COc1ccc(C=C(C#N)C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L20 mock treatment 1086237.0 73700.0 0.16 936601.0 -40600.0 -0.09 0.0453 0.2493 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L21 compound treatment 642854.0 -370000.0 -0.78 441328.0 -536000.0 -1.22 -1.4156 -0.9772 5 Bio2_000440 CC(C)(C)c1cc(C=C(C#N)C#N)cc(c1O)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L22 mock treatment 975879.0 -36600.0 -0.08 889942.0 -87300.0 -0.2 -0.1952 -0.9161 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L23 mock treatment 855489.0 -157000.0 -0.33 892825.0 -84400.0 -0.19 -0.371 -0.9657 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 L24 mock treatment 524140.0 -488000.0 -1.04 608231.0 -369000.0 -0.84 -1.3252 -0.9946 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M01 mock treatment 613633.0 -399000.0 -0.85 559880.0 -417000.0 -0.95 -1.2688 -0.9983 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M02 mock treatment 950169.0 -62300.0 -0.13 975809.0 -1400.0 0.0 -0.0957 -0.7239 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M03 compound treatment 1077460.0 65000.0 0.14 966180.0 -11000.0 -0.03 0.0797 0.569 423 Bio2_000441 COC(=O)[C@@H](N)CCCNC(=N)N[N+](=O)[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M04 mock treatment 1188381.0 176000.0 0.37 1039233.0 62000.0 0.14 0.3634 0.9115 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M05 compound treatment 945324.0 -67200.0 -0.14 1093412.0 116000.0 0.26 0.0861 0.2869 321 Bio2_000442 O=c1cc(oc2c(cccc12)c3ccccc3)N4CCOCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M06 mock treatment 1298455.0 286000.0 0.61 1172387.0 195000.0 0.44 0.7424 0.9882 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M07 compound treatment 162462.0 -850000.0 -1.8 170019.0 -807000.0 -1.84 -2.5719 -1.0 243 Bio2_000443 O=C1C=C(Nc2ccccc2)C(=O)c3cccnc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M08 mock treatment 1318921.0 306000.0 0.65 1024089.0 46900.0 0.11 0.5347 0.8123 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M09 compound treatment 145423.0 -867000.0 -1.84 136703.0 -841000.0 -1.91 -2.651 -0.9998 1059329 Bio2_000444 Nc1ncnc2n(cc(I)c12)C3OC(CO)C(O)C3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M10 mock treatment 1391216.0 379000.0 0.8 1168835.0 192000.0 0.44 0.8758 0.9588 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M11 compound treatment 157937.0 -855000.0 -1.81 168287.0 -809000.0 -1.84 -2.5815 -1.0 3104900 Bio2_000445 C/C(=C\CCC1C=CC(OC1O)C2=CC(=O)OC2O)/CCC3=C(C)CCCC3(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M12 mock treatment 1078394.0 65900.0 0.14 1130538.0 153000.0 0.35 0.3453 0.9194 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M13 compound treatment 1171994.0 159000.0 0.34 1040079.0 62900.0 0.14 0.3402 0.9266 192 Bio2_000446 CCCCC(C)/C=C(\C)/C=C(\C)/C(=O)NC1=CC(O)(\C=C\C=C\C=C\C(=O)NC2=C(O)CCC2=O)C3OC3C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M14 mock treatment 1104326.0 91800.0 0.19 1028264.0 51100.0 0.12 0.2197 0.9695 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M15 compound treatment 922358.0 -90100.0 -0.19 1009119.0 31900.0 0.07 -0.0838 -0.4101 907409 Bio2_000447 CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M16 mock treatment 1080207.0 67700.0 0.14 961754.0 -15500.0 -0.04 0.0767 0.5187 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M17 compound treatment 856374.0 -156000.0 -0.33 730035.0 -247000.0 -0.56 -0.6314 -0.9681 419 Bio2_000448 CC1=NN(C(=O)C1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M18 mock treatment 1216438.0 204000.0 0.43 983585.0 6380.0 0.01 0.316 0.7304 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M19 compound treatment 104377.0 -908000.0 -1.93 99924.0 -877000.0 -1.99 -2.7717 -0.9998 3002144 Bio2_000449 CN1C(=O)[C@@]23CC4=CC=C[C@H](O)[C@H]4N3C(=O)[C@@]1(CO)[S+](C)S2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M20 mock treatment 1182290.0 170000.0 0.36 1116559.0 139000.0 0.32 0.4786 0.998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M21 compound treatment 1005541.0 -6960.0 -0.01 1090848.0 114000.0 0.26 0.1723 0.6657 638 Bio2_000450 C/C(=C(\C#N)/C(=O)Nc1cc(Br)ccc1Br)/O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M22 mock treatment 1018983.0 6490.0 0.01 1064837.0 87600.0 0.2 0.1506 0.7541 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M23 mock treatment 862307.0 -150000.0 -0.32 820405.0 -157000.0 -0.36 -0.4772 -0.9984 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 M24 mock treatment 538026.0 -474000.0 -1.01 469415.0 -508000.0 -1.15 -1.5276 -0.9976 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N01 mock treatment 641492.0 -371000.0 -0.79 588198.0 -389000.0 -0.88 -1.1815 -0.9983 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N02 mock treatment 1008452.0 -4050.0 -0.01 993205.0 16000.0 0.04 0.0197 0.5259 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N03 compound treatment 1040204.0 27700.0 0.06 1072009.0 94800.0 0.22 0.1939 0.8681 3104901 Bio2_000451 CCCc1cc(OC)ccc1C.CC12CCCCC2CCC1NCCCCCCN3C(=O)C=CC3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N04 mock treatment 1221078.0 209000.0 0.44 1055735.0 78500.0 0.18 0.4389 0.9204 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N05 compound treatment 1155153.0 143000.0 0.3 1012893.0 35700.0 0.08 0.2712 0.8662 325 Bio2_000452 N/C(=C(/C#N)\C(=C(/N)\Sc1ccccc1N)\C#N)/Sc2ccccc2N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N06 mock treatment 1365690.0 353000.0 0.75 1107417.0 130000.0 0.3 0.7388 0.9176 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N07 compound treatment 94077.0 -918000.0 -1.95 119286.0 -858000.0 -1.95 -2.756 -1.0 2430 Bio2_000453 CC(C)C1NC(=O)C(C)OC(=O)C(NC(=O)C(OC(=O)C(NC(=O)C(C)OC(=O)C(NC(=O)C(OC(=O)C(NC(=O)C(C)OC(=O)C(NC(=O)C(OC1=O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N08 mock treatment 1291645.0 279000.0 0.59 1100855.0 124000.0 0.28 0.6172 0.9421 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N09 compound treatment 256353.0 -756000.0 -1.6 233688.0 -744000.0 -1.69 -2.3288 -0.9996 3002149 Bio2_000454 *[C@@H]1[C@H]([C@@H]2CN(C[C@](O)(CC)C2)CCc3c1[nH]c4ccccc34)c5cc6c(cc5OC)N(C)[C@@H]7[C@@]86CCN9CC=C[C@](CC)([C@H]98)[C@@H](O)[C@]7(O)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N10 mock treatment 1346327.0 334000.0 0.71 1155721.0 179000.0 0.41 0.7874 0.9652 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N11 compound treatment 1236936.0 224000.0 0.48 1064846.0 87600.0 0.2 0.4773 0.9254 3002210 Bio2_000455 *CCCCCCNOc1cccc2c(Cl)cccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N12 mock treatment 1464928.0 452000.0 0.96 1167867.0 191000.0 0.43 0.9847 0.9356 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N13 compound treatment 1478428.0 466000.0 0.99 1119404.0 142000.0 0.32 0.927 0.892 293 Bio2_000456 COC[C@H]1OC(=O)c2coc3C(=O)C4=C([C@@H](C[C@@]5(C)C4CCC5=O)OC(=O)C)[C@]1(C)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N14 mock treatment 1291869.0 279000.0 0.59 1157251.0 180000.0 0.41 0.7082 0.9837 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N15 compound treatment 1234988.0 222000.0 0.47 1238542.0 261000.0 0.59 0.7537 0.9935 677 Bio2_000457 C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc2ccncc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N16 mock treatment 1131226.0 119000.0 0.25 1221009.0 244000.0 0.55 0.5699 0.9362 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N17 compound treatment 1120317.0 108000.0 0.23 1194634.0 217000.0 0.49 0.5112 0.9386 3000363 Bio2_000458 COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N18 mock treatment 1293063.0 281000.0 0.59 1328386.0 351000.0 0.8 0.9851 0.9895 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N19 compound treatment 101673.0 -911000.0 -1.93 113819.0 -863000.0 -1.96 -2.7534 -1.0 207 Bio2_000459 CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)/C=C/S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N20 mock treatment 1181994.0 169000.0 0.36 1118428.0 141000.0 0.32 0.4811 0.9984 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N21 compound treatment 1047881.0 35400.0 0.08 960616.0 -16600.0 -0.04 0.0264 0.314 352 Bio2_000460 CN(C)c1cccc(c1)C(=O)Nc2ccc(C)c(NC(=O)c3ccc(O)cc3)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N22 mock treatment 1077714.0 65200.0 0.14 1024948.0 47700.0 0.11 0.1745 0.9928 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N23 mock treatment 992831.0 -19700.0 -0.04 1030794.0 53600.0 0.12 0.0567 0.4401 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 N24 mock treatment 546184.0 -466000.0 -0.99 531124.0 -446000.0 -1.01 -1.4162 -0.9999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O01 mock treatment 525981.0 -487000.0 -1.03 522038.0 -455000.0 -1.03 -1.4611 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O02 mock treatment 1034611.0 22100.0 0.05 972043.0 -5170.0 -0.01 0.0248 0.5141 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O03 compound treatment 382184.0 -630000.0 -1.34 327234.0 -650000.0 -1.48 -1.9898 -0.9987 3002219 Bio2_000461 *CCC(NC(=O)c1ccc(cc1)N(C)Cc2cnc3nc(N)nc(N)c3n2)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O04 mock treatment 1108360.0 95900.0 0.2 1079392.0 102000.0 0.23 0.308 0.9978 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O05 compound treatment 1291240.0 279000.0 0.59 1158227.0 181000.0 0.41 0.7089 0.9844 1001921 Bio2_000462 Clc1ccc(cn1)C2CC3CCC2N3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O06 mock treatment 1331193.0 319000.0 0.68 1149307.0 172000.0 0.39 0.7544 0.9663 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O07 compound treatment 1076713.0 64200.0 0.14 994505.0 17300.0 0.04 0.1241 0.8756 381 Bio2_000463 CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3CCCC(=O)O3)[C@@H]12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O08 mock treatment 1266028.0 254000.0 0.54 1198545.0 221000.0 0.5 0.7359 0.9995 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O09 compound treatment 119324.0 -893000.0 -1.89 162560.0 -815000.0 -1.85 -2.6486 -0.9999 1000019 Bio2_000464 CO[C@@]12[C@H]3N[C@H]3CN2C4=C([C@H]1COC(=O)N)C(=O)C(=C(C)C4=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O10 mock treatment 1294488.0 282000.0 0.6 1199838.0 223000.0 0.51 0.7806 0.9966 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O11 compound treatment 1270404.0 258000.0 0.55 1225968.0 249000.0 0.57 0.7865 0.9999 281 Bio2_000465 Ic1cccc2c(cccc12)S(=O)(=O)N3CCCNCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O12 mock treatment 1170642.0 158000.0 0.34 1192846.0 216000.0 0.49 0.5837 0.9828 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O13 compound treatment 1215228.0 203000.0 0.43 1139869.0 163000.0 0.37 0.5654 0.9972 3002225 Bio2_000466 Clc1cccc2c(cccc12)S(=O)(=O)N3CC*CCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O14 mock treatment 1112283.0 99800.0 0.21 1173904.0 197000.0 0.45 0.4658 0.9416 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O15 compound treatment 1216876.0 204000.0 0.43 1227149.0 250000.0 0.57 0.7082 0.991 438 Bio2_000467 CCOC(=O)C1=C(C)NC(=S)NC1c2cccc(O)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O16 mock treatment 1244555.0 232000.0 0.49 1219366.0 242000.0 0.55 0.7372 0.9984 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O17 compound treatment 1071678.0 59200.0 0.13 1018100.0 40900.0 0.09 0.1545 0.9891 656 Bio2_000468 Oc1c(Br)cc(/C=C/2\C(=O)Nc3ccc(I)cc23)cc1Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O18 mock treatment 1160027.0 148000.0 0.31 1140629.0 163000.0 0.37 0.4839 0.9963 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O19 compound treatment 102273.0 -910000.0 -1.93 96867.0 -880000.0 -2.0 -2.7797 -0.9998 3104902 Bio2_000469 CC[C@]1(CC[C@@H](O1)[C@]2(C)CC[C@]3(C[C@H](O)[C@@H](C)[C@H](O3)[C@@H](C)C/C=C(\C)/OO)O2)[C@@H]4O[C@H](C[C@@H]4C)[C@H]5O[C@@](O)(CO)[C@H](C)C[C@@H]5C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O20 mock treatment 1177665.0 165000.0 0.35 1012462.0 35300.0 0.08 0.3043 0.8471 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O21 compound treatment 127089.0 -885000.0 -1.88 151660.0 -826000.0 -1.88 -2.6544 -1.0 1907781 Bio2_000470 CO[C@@H]1C[C@@H](CC[C@H]1O)/C=C(\C)/[C@H]2OC(=O)C3CCCCN3C(=O)C(=O)[C@]4(O)O[C@@H]([C@H](C[C@H]4C)OC)[C@H](C[C@@H](C)C\C(=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)\C)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O22 mock treatment 1012871.0 373.0 0.0 939316.0 -37900.0 -0.09 -0.0604 -0.7006 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O23 mock treatment 1030645.0 18100.0 0.04 783572.0 -194000.0 -0.44 -0.2841 -0.6429 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 O24 mock treatment 454918.0 -558000.0 -1.18 465392.0 -512000.0 -1.16 -1.6586 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P01 mock treatment 436010.0 -576000.0 -1.22 373619.0 -604000.0 -1.37 -1.8345 -0.9983 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P02 mock treatment 478848.0 -534000.0 -1.13 475421.0 -502000.0 -1.14 -1.6067 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P03 compound treatment 672089.0 -340000.0 -0.72 608410.0 -369000.0 -0.84 -1.1032 -0.9972 201 Bio2_000471 COC(=O)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)CF 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P04 mock treatment 672550.0 -340000.0 -0.72 689312.0 -288000.0 -0.65 -0.9724 -0.9988 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P05 compound treatment 927054.0 -85400.0 -0.18 863738.0 -113000.0 -0.26 -0.3105 -0.985 2217 Bio2_000472 CS(=O)(=O)Nc1ccc(cc1OC2CCCCC2)[N+](=O)[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P06 mock treatment 985409.0 -27100.0 -0.06 988161.0 11000.0 0.02 -0.023 -0.3674 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P07 compound treatment 187841.0 -825000.0 -1.75 139042.0 -838000.0 -1.91 -2.5837 -0.9991 1917 Bio2_000473 CC1=C(C)C(=O)C(=C(C)C1=O)CCCCC#CCCCC#CCO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P08 mock treatment 1083432.0 70900.0 0.15 1025001.0 47800.0 0.11 0.1832 0.9873 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P09 compound treatment 280964.0 -732000.0 -1.55 274168.0 -703000.0 -1.6 -2.2268 -0.9999 3002232 Bio2_000474 *CC/C(=C/Cc1c(O)c2C(=O)OCc2c(C)c1OC)/C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P10 mock treatment 1153567.0 141000.0 0.3 1063392.0 86200.0 0.2 0.35 0.979 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P11 compound treatment 1068054.0 55600.0 0.12 1058939.0 81700.0 0.19 0.2147 0.9758 2288 Bio2_000475 CC(=CCC(O)C1=CC(=O)c2c(O)ccc(O)c2C1=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P12 mock treatment 1068203.0 55700.0 0.12 954596.0 -22600.0 -0.05 0.0472 0.3661 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P13 compound treatment 1117436.0 105000.0 0.22 1010738.0 33500.0 0.08 0.2112 0.8981 3104904 Bio2_000476 C1C[C@H]2CCCCCC[C@H]3CCN4CCC[C@H](CCCCCC[C@H]5CCN(C1)[C@@H]2O5)[C@H]4O3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P14 mock treatment 1067864.0 55400.0 0.12 1187706.0 210000.0 0.48 0.4214 0.8552 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P15 compound treatment 858115.0 -154000.0 -0.33 885556.0 -91700.0 -0.21 -0.3788 -0.9762 1907782 Bio2_000477 Oc1ccc(/C=C(/C#N)\C(=O)OC\C=C\c2ccccc2)cc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P16 mock treatment 1010145.0 -2350.0 0.0 1241961.0 265000.0 0.6 0.4221 0.7012 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P17 compound treatment 153899.0 -859000.0 -1.82 185806.0 -791000.0 -1.8 -2.5594 -1.0 3104917 Bio2_000478 C/C=C/C\C=C\CCC(=O)[C@H]1O[C@H]1C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P18 mock treatment 1051107.0 38600.0 0.08 1056711.0 79500.0 0.18 0.1857 0.9358 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P19 compound treatment 767296.0 -245000.0 -0.52 788052.0 -189000.0 -0.43 -0.6717 -0.9956 1395 Bio2_000479 CC(COc1ccccc1)N(CCCl)Cc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P20 mock treatment 834798.0 -178000.0 -0.38 859595.0 -118000.0 -0.27 -0.4555 -0.9859 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P21 compound treatment 629592.0 -383000.0 -0.81 647921.0 -329000.0 -0.75 -1.1034 -0.9992 1303231 Bio2_000480 CN(C)CC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P22 mock treatment 601884.0 -411000.0 -0.87 563387.0 -414000.0 -0.94 -1.2808 -0.9992 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P23 mock treatment 515895.0 -497000.0 -1.05 466517.0 -511000.0 -1.16 -1.5654 -0.9988 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1362 P24 mock treatment 427364.0 -585000.0 -1.24 394125.0 -583000.0 -1.33 -1.8145 -0.9994 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A01 compound treatment 543144.0 -219000.0 -0.46 353876.0 -271000.0 -0.62 -0.7638 -0.9903 1213399 ChemDiv2_003521 CCCc1cc2c(=O)c(coc2cc1OC)c3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A02 compound treatment 646749.0 -115000.0 -0.24 371620.0 -253000.0 -0.58 -0.58 -0.9274 1609007 ChemDiv2_003522 Clc1ccc(OCc2nnc(NC(=O)C3CCCCC3)s2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A03 compound treatment 561169.0 -201000.0 -0.43 591461.0 -33300.0 -0.08 -0.3548 -0.8199 1294366 ChemDiv2_003523 COc1ccc(NC(=O)CSc2nc3cc4ccccc4cc3c(=O)n2CC=C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A04 compound treatment 654241.0 -108000.0 -0.23 691241.0 66500.0 0.15 -0.0549 -0.2003 1271582 ChemDiv2_003524 O=C1N(CCCc2nc3ccccc3c(=O)n2Cc4ccco4)C(=O)c5ccccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A05 compound treatment 742175.0 -20000.0 -0.04 502744.0 -122000.0 -0.28 -0.2261 -0.8057 1985473 ChemDiv2_003525 Cc1ccc(NC(=O)c2cnn(c2NC(=O)c3ccco3)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A06 compound treatment 739820.0 -22300.0 -0.05 640743.0 16000.0 0.04 -0.0078 -0.1308 1392176 ChemDiv2_003526 CCn1c(SCC(=O)OC)nc2n(C)c(=O)n(C)c(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A07 compound treatment 615800.0 -146000.0 -0.31 604055.0 -20700.0 -0.05 -0.2527 -0.8052 1620420 ChemDiv2_003527 C=CCn1c(Cc2ccccc2)nc3n(ncc3c1=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A08 compound treatment 995201.0 233000.0 0.49 791782.0 167000.0 0.38 0.6178 0.9915 1615833 ChemDiv2_003528 CCC(c1nnc(N)s1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A09 compound treatment 852447.0 90300.0 0.19 869103.0 244000.0 0.56 0.5281 0.8989 1595774 ChemDiv2_003529 CCCSc1nc2n(C)c(=O)[nH]c(=O)c2n1C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A10 compound treatment 856449.0 94300.0 0.2 836056.0 211000.0 0.48 0.481 0.9245 1671963 ChemDiv2_003530 Nc1nnc(s1)c2ccccc2SCc3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A11 compound treatment 905989.0 144000.0 0.3 781830.0 157000.0 0.36 0.4681 0.9969 1705701 ChemDiv2_003531 COc1cc(OC)cc(c1)C(=O)N2CCN(C)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A12 compound treatment 439194.0 -323000.0 -0.68 627069.0 2300.0 0.01 -0.4804 -0.7017 1456152 ChemDiv2_003532 CC(=O)Nc1nc2ccccc2n1CCN3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A13 compound treatment 555680.0 -206000.0 -0.44 654951.0 30200.0 0.07 -0.261 -0.5891 1420880 ChemDiv2_003533 CCn1c2ccccc2c3nnc(SCC(=O)Nc4ccc(cc4)S(=O)(=O)N)nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A14 compound treatment 676181.0 -86000.0 -0.18 732268.0 107000.0 0.24 0.0439 0.1441 1382489 ChemDiv2_003534 CCN(CC)CCn1c2nc(C)cn2c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A15 compound treatment 1039482.0 277000.0 0.59 927466.0 303000.0 0.69 0.9023 0.9969 1985474 ChemDiv2_003535 CCC(=O)Nc1nc2CC(CC(=O)c2s1)c3ccc(OC)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A16 compound treatment 664120.0 -98000.0 -0.21 653035.0 28300.0 0.06 -0.1015 -0.4667 1613265 ChemDiv2_003536 CC(C)Cn1c(=O)c2cc3c(=O)n(CC(C)C)c(=O)c3cc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A17 compound treatment 759121.0 -3030.0 -0.01 725528.0 101000.0 0.23 0.1574 0.687 1480506 ChemDiv2_003537 CCC(=O)OCCn1c(=O)c2cc3c(=O)n(CCOC(=O)CC)c(=O)c3cc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A18 compound treatment 698287.0 -63900.0 -0.14 587085.0 -37700.0 -0.09 -0.1563 -0.9756 1123996 ChemDiv2_003538 CC(Oc1ccc2c(=O)c(Oc3ccccc3)c(C)oc2c1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A19 compound treatment 760062.0 -2090.0 0.0 725098.0 100000.0 0.23 0.1582 0.6932 1445496 ChemDiv2_003539 C=CCn1c(=N)n(CC(=O)c2ccco2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A20 compound treatment 878100.0 116000.0 0.25 668133.0 43400.0 0.1 0.2435 0.9195 1143616 ChemDiv2_003540 CN(C1CCS(=O)(=O)C1)C(=O)COc2cccc(Br)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A21 compound treatment 707245.0 -54900.0 -0.12 456848.0 -168000.0 -0.38 -0.3523 -0.8826 1515649 ChemDiv2_003541 COc1ccc(OC(C)C(=O)Nc2nnc[nH]2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A22 compound treatment 686737.0 -75400.0 -0.16 506337.0 -118000.0 -0.27 -0.3035 -0.969 1928306 ChemDiv2_003542 Oc1nc(SCC(=O)c2ccccc2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A23 mock treatment 476057.0 -286000.0 -0.61 361777.0 -263000.0 -0.6 -0.8517 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 A24 mock treatment 506652.0 -256000.0 -0.54 397231.0 -228000.0 -0.52 -0.7488 -0.9997 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B01 compound treatment 597239.0 -165000.0 -0.35 505607.0 -119000.0 -0.27 -0.4388 -0.9921 1321267 ChemDiv2_003543 COc1ccc(Cc2c(O)nc(SC)n(c3ccccc3)c2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B02 compound treatment 903783.0 142000.0 0.3 905342.0 281000.0 0.64 0.6634 0.9409 1985475 ChemDiv2_003544 CCC(=O)Nc1nc2ccccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B03 compound treatment 933890.0 172000.0 0.36 879142.0 254000.0 0.58 0.6664 0.9751 1985476 ChemDiv2_003545 CCC(Sc1ccccn1)C(=O)Nc2ccc(Cl)cn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B04 compound treatment 1115463.0 353000.0 0.75 892635.0 268000.0 0.61 0.9603 0.9947 1134754 ChemDiv2_003546 O=C(CN1C(=O)c2ccccc2C1=O)Nc3ccc(cc3)S(=O)(=O)Nc4ncccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B05 compound treatment 1077428.0 315000.0 0.67 1051392.0 427000.0 0.97 1.1585 0.9835 1274302 ChemDiv2_003547 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3ccc(cc3)S(=O)(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B06 compound treatment 921357.0 159000.0 0.34 1104483.0 480000.0 1.09 1.0099 0.8845 1985477 ChemDiv2_003548 COC(=O)C1=CNC=C(C1c2cccc3ccccc23)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B07 compound treatment 998747.0 237000.0 0.5 1053271.0 428000.0 0.97 1.0435 0.9524 1234602 ChemDiv2_003549 Cc1nc2ccc(Cc3ccc4nc(C)oc(=O)c4c3)cc2c(=O)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B08 compound treatment 1028339.0 266000.0 0.56 1007674.0 383000.0 0.87 1.0146 0.978 1714761 ChemDiv2_003550 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(C)cc3)C(=O)Nc4cc(C)ccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B09 compound treatment 973871.0 212000.0 0.45 983681.0 359000.0 0.82 0.8944 0.9604 1448706 ChemDiv2_003551 CCN(Cc1ccccc1)C(=O)CN2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B10 compound treatment 915580.0 153000.0 0.33 1257566.0 633000.0 1.44 1.2473 0.8456 1612493 ChemDiv2_003552 Cc1cccc(c1)C(=O)Nc2sc3CCCc3c2C(=O)N4CCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B11 compound treatment 971556.0 209000.0 0.44 993347.0 369000.0 0.84 0.9064 0.9559 1285041 ChemDiv2_003553 COC(=O)CNC(=O)c1cc(nc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B12 compound treatment 920257.0 158000.0 0.34 1251586.0 627000.0 1.43 1.2447 0.8502 1665381 ChemDiv2_003554 CCCC(=O)N1C(C2=C(CCCC2=O)Nc3ccccc13)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B13 compound treatment 955508.0 193000.0 0.41 1044521.0 420000.0 0.95 0.9646 0.9288 1985478 ChemDiv2_003555 C=CCSc1nnc2n(c3ccccc3)c(=O)c4c5CCCc5sc4n12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B14 compound treatment 897693.0 136000.0 0.29 1045019.0 420000.0 0.96 0.8788 0.8808 1033505 ChemDiv2_003556 O=c1[nH]c2ccccc2c(=O)n1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B15 compound treatment 1072533.0 310000.0 0.66 1088389.0 464000.0 1.05 1.2106 0.9743 1478188 ChemDiv2_003557 O=C(CN1C(=O)c2ccccc2C1=O)N3CCCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B16 compound treatment 981776.0 220000.0 0.47 1095327.0 471000.0 1.07 1.0857 0.9305 1526658 ChemDiv2_003558 Cc1ccccc1c2nc3cc(NC(=O)c4cccs4)ccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B17 compound treatment 921097.0 159000.0 0.34 1007606.0 383000.0 0.87 0.8537 0.9147 1443126 ChemDiv2_003559 COc1ccccc1C(=O)Nc2cccc3nsnc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B18 compound treatment 1020024.0 258000.0 0.55 1025168.0 400000.0 0.91 1.0302 0.9702 1985479 ChemDiv2_003560 COc1ncnc2sc(C(=O)O)c(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B19 compound treatment 1195133.0 433000.0 0.92 947901.0 323000.0 0.73 1.1685 0.9939 1187503 ChemDiv2_003561 CCN(CC)Cc1c(O)c(CC)cc2c(=O)c(coc12)c3nc4ccccc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B20 compound treatment 1185110.0 423000.0 0.9 948769.0 324000.0 0.74 1.1549 0.9952 1985480 ChemDiv2_003562 CCN(C(=O)Cc1c(C(=O)O)n(CC)c2ccccc12)c3cccc(Cl)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B21 compound treatment 1084297.0 322000.0 0.68 930940.0 306000.0 0.7 0.9751 1.0 1985481 ChemDiv2_003563 Clc1cccc(Oc2ncnc3c4ccccc4oc23)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B22 compound treatment 1060140.0 298000.0 0.63 884905.0 260000.0 0.59 0.8649 0.9995 1411618 ChemDiv2_003564 Cc1ccc(cc1)c2nn(CC(=O)N)c(=O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B23 mock treatment 960738.0 199000.0 0.42 970284.0 346000.0 0.79 0.8531 0.9573 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 B24 mock treatment 590821.0 -171000.0 -0.36 467563.0 -157000.0 -0.36 -0.5096 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C01 compound treatment 680462.0 -81700.0 -0.17 637972.0 13200.0 0.03 -0.1012 -0.576 1661025 ChemDiv2_003565 CCOC(=O)c1ccc(o1)c2coc3cc(O)c(CC)cc3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C02 compound treatment 879091.0 117000.0 0.25 902782.0 278000.0 0.63 0.6222 0.9165 1146986 ChemDiv2_003566 OCCCN1C(=O)C2C3CC(C=C3)C2C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C03 compound treatment 939252.0 177000.0 0.38 968391.0 344000.0 0.78 0.8179 0.9436 1167604 ChemDiv2_003567 CCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2ncn(Cc3ccccc3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C04 compound treatment 974108.0 212000.0 0.45 842990.0 218000.0 0.5 0.6685 0.9988 1564137 ChemDiv2_003568 CC(C)C(=O)Oc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C05 compound treatment 964749.0 203000.0 0.43 939670.0 315000.0 0.72 0.8099 0.9701 1322613 ChemDiv2_003569 Cc1c(CCN)c2cccc3CCCn1c32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C06 compound treatment 1004466.0 242000.0 0.51 815064.0 190000.0 0.43 0.6692 0.9964 1729074 ChemDiv2_003570 Cn1c(=O)n(C)c2nc(SCc3ccc(F)cc3)n(Cc4ccccc4)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C07 compound treatment 987345.0 225000.0 0.48 836685.0 212000.0 0.48 0.6782 1.0 1985482 ChemDiv2_003571 Cc1cc(C)nc(Nc2ccccc2Br)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C08 compound treatment 843696.0 81500.0 0.17 841433.0 217000.0 0.49 0.4705 0.9014 1186388 ChemDiv2_003572 COc1ccc(N2C(=O)c3ccc(cc3C2=O)c4nc5ccccc5c(=O)o4)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C09 compound treatment 962529.0 200000.0 0.42 937048.0 312000.0 0.71 0.8024 0.9698 1566137 ChemDiv2_003573 CCOC(=O)C(C)Sc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(O)COc3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C10 compound treatment 1058560.0 296000.0 0.63 873122.0 248000.0 0.56 0.8436 0.9986 1985483 ChemDiv2_003574 N#Cc1ccc(Sc2nc3ccccc3[nH]2)cc1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C11 compound treatment 897017.0 135000.0 0.29 779155.0 154000.0 0.35 0.4504 0.9948 1341100 ChemDiv2_003575 OC(COc1ccccc1C(=O)O)Cn2cnc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C12 compound treatment 895492.0 133000.0 0.28 900889.0 276000.0 0.63 0.6438 0.9351 1397415 ChemDiv2_003576 CCC(=O)Nc1nc2ccccc2n1CCN3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C13 compound treatment 951135.0 189000.0 0.4 966910.0 342000.0 0.78 0.8333 0.9524 1625849 ChemDiv2_003577 O=C1N(CSc2nc3ccccc3[nH]2)C(=O)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C14 compound treatment 1036340.0 274000.0 0.58 837770.0 213000.0 0.48 0.7534 0.9959 1286795 ChemDiv2_003578 CN(C)C(=O)c1cnn(c1NC(=O)c2ccc(Br)cc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C15 compound treatment 1133349.0 371000.0 0.79 916430.0 292000.0 0.66 1.0253 0.9964 1946553 ChemDiv2_003579 COc1nc(c2ccccc2)c3cc(C)ccc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C16 compound treatment 987975.0 226000.0 0.48 883761.0 259000.0 0.59 0.7549 0.9947 1706155 ChemDiv2_003580 CC(=O)Oc1ccc(cc1)N2C(=O)c3ccc(cc3C2=O)c4nc5ccccc5c(=O)o4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C17 compound treatment 990393.0 228000.0 0.48 968048.0 343000.0 0.78 0.894 0.9736 1985484 ChemDiv2_003581 CC(C)(C)C(=O)OCCn1c(=O)c2cc3c(=O)n(CCOC(=O)C(C)(C)C)c(=O)c3cc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C18 compound treatment 1170002.0 408000.0 0.86 885828.0 261000.0 0.59 1.0311 0.9832 1985485 ChemDiv2_003582 CCC(C)n1c(=O)[nH]c2CCCc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C19 compound treatment 1259041.0 497000.0 1.05 853434.0 229000.0 0.52 1.1125 0.947 1606911 ChemDiv2_003583 Cc1ccc(Cn2c(=N)n(CC(=O)c3ccco3)c4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C20 compound treatment 1154500.0 392000.0 0.83 736287.0 112000.0 0.25 0.7674 0.8826 1777351 ChemDiv2_003584 CCCCn1c(=O)[nH]c2CCCc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C21 compound treatment 1214887.0 453000.0 0.96 726537.0 102000.0 0.23 0.8423 0.8531 1526424 ChemDiv2_003585 CCCn1c(nc2c(=O)n(C)c(=O)[nH]c12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C22 compound treatment 1043189.0 281000.0 0.6 776438.0 152000.0 0.34 0.6651 0.9662 1033442 ChemDiv2_003586 Oc1nc(SCc2ccccc2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C23 mock treatment 1074673.0 313000.0 0.66 580629.0 -44100.0 -0.1 0.3975 0.5932 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 C24 mock treatment 691744.0 -70400.0 -0.15 406170.0 -219000.0 -0.5 -0.457 -0.8806 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D01 compound treatment 693842.0 -68300.0 -0.14 715356.0 90600.0 0.21 0.0432 0.1717 1236687 ChemDiv2_003587 Fc1cccc(c1)C(=O)N2CCN(CC2)C(=O)C3CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D02 compound treatment 802020.0 39900.0 0.08 1061447.0 437000.0 0.99 0.7618 0.7645 1724706 ChemDiv2_003588 Cc1ccc2nsnc2c1NC(=O)c3cccc(Cl)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D03 compound treatment 852158.0 90000.0 0.19 957788.0 333000.0 0.76 0.6703 0.8585 1985486 ChemDiv2_003589 CCC(Sc1nc2ccccc2s1)C(=O)Nc3ccccc3C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D04 compound treatment 857899.0 95700.0 0.2 1037399.0 413000.0 0.94 0.8069 0.8406 1397326 ChemDiv2_003590 Cc1cccc(NC(=O)c2ccn(n2)C(=O)Oc3ccccc3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D05 compound treatment 974969.0 213000.0 0.45 1053712.0 429000.0 0.98 1.0086 0.9387 1089467 ChemDiv2_003591 Cc1cc(O)nc(n1)N2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D06 compound treatment 1023600.0 261000.0 0.55 1098675.0 474000.0 1.08 1.1538 0.9522 1149234 ChemDiv2_003592 OC(=O)C1C2OC3(CN(Cc4ccccc4)C(=O)C13)C=C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D07 compound treatment 996582.0 234000.0 0.5 1175276.0 551000.0 1.25 1.2364 0.9181 1471918 ChemDiv2_003593 Clc1cc(nc(n1)N2CCCC2)N3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D08 compound treatment 920409.0 158000.0 0.34 1075948.0 451000.0 1.03 0.9626 0.8919 1666375 ChemDiv2_003594 CC(NC(=O)c1cc2cccc(CC=C)c2oc1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D09 compound treatment 1098372.0 336000.0 0.71 1090328.0 466000.0 1.06 1.2524 0.9815 1588410 ChemDiv2_003595 OCCNc1cc(ncn1)n2nc(cc2c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D10 compound treatment 1105924.0 344000.0 0.73 1093537.0 469000.0 1.07 1.2689 0.9828 1697507 ChemDiv2_003596 O=c1n(c2ccccc2)c(nc3n(ncc13)c4ccccc4)c5ccco5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D11 compound treatment 1200819.0 439000.0 0.93 1129814.0 505000.0 1.15 1.4695 0.9945 1650656 ChemDiv2_003597 Cc1nnc(SC2CC(=O)N(C2=O)c3ccc(C)cc3)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D12 compound treatment 1313091.0 551000.0 1.17 1258810.0 634000.0 1.44 1.8452 0.9946 1985487 ChemDiv2_003598 CCSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D13 compound treatment 1353884.0 592000.0 1.25 1210764.0 586000.0 1.33 1.8291 0.9995 1444605 ChemDiv2_003599 CCSc1nc2sc3CN(C)CCc3c2c(=O)n1c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D14 compound treatment 1142612.0 380000.0 0.81 1118097.0 493000.0 1.12 1.3634 0.9869 1515816 ChemDiv2_003600 CCOc1cccc(c1)C(=O)Nc2cccc(c3nc4ccccc4[nH]3)c2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D15 compound treatment 1110693.0 349000.0 0.74 1201845.0 577000.0 1.31 1.4502 0.9631 1331335 ChemDiv2_003601 OC(Cn1c(=N)n(Cc2ccccc2)c3ccccc13)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D16 compound treatment 1206647.0 444000.0 0.94 1025514.0 401000.0 0.91 1.3106 0.9999 1561694 ChemDiv2_003602 CCCC1CC(CSc2nc3ccccc3[nH]2)OC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D17 compound treatment 1197872.0 436000.0 0.92 1077897.0 453000.0 1.03 1.3816 0.9985 1174383 ChemDiv2_003603 CCOc1ccc(cc1Br)C(=O)Nc2cccc3nsnc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D18 compound treatment 1299055.0 537000.0 1.14 984064.0 359000.0 0.82 1.3824 0.9868 1309572 ChemDiv2_003604 O=C(Cn1cnc2scc(c3ccccc3)c2c1=O)N4CCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D19 compound treatment 1203849.0 442000.0 0.94 954568.0 330000.0 0.75 1.1923 0.9939 1612854 ChemDiv2_003605 COC(=O)c1c(C)oc2ccc(O)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D20 compound treatment 1217521.0 455000.0 0.97 913511.0 289000.0 0.66 1.1468 0.9823 1985488 ChemDiv2_003606 COc1ccccc1N2CCN(CC2)c3ncc(C(=O)Nc4cc(OC)c(OC)c(OC)c4)c5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D21 compound treatment 1214829.0 453000.0 0.96 927596.0 303000.0 0.69 1.1654 0.9867 1011785 ChemDiv2_003607 O=C(CN1C(=O)c2ccccc2C1=O)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D22 compound treatment 1109523.0 347000.0 0.74 789322.0 165000.0 0.37 0.7853 0.9507 1731728 ChemDiv2_003608 CCCOc1nnc(c2ccc(C)c(c2)S(=O)(=O)N(C)C)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D23 mock treatment 1095492.0 333000.0 0.71 597210.0 -27600.0 -0.06 0.4554 0.6419 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 D24 mock treatment 793951.0 31800.0 0.07 438658.0 -186000.0 -0.42 -0.2515 -0.5871 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E01 compound treatment 312481.0 -450000.0 -0.95 356743.0 -268000.0 -0.61 -1.105 -0.9766 1569706 ChemDiv2_003609 CCCCn1c(=N)n(CC(O)c2ccccc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E02 compound treatment 924397.0 162000.0 0.34 775897.0 151000.0 0.34 0.4862 1.0 1948008 ChemDiv2_003610 Fc1ccc(NC(=O)CSc2nsc(SCC(=O)Nc3ccc(F)cc3)n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E03 compound treatment 967363.0 205000.0 0.44 844384.0 220000.0 0.5 0.6607 0.9976 1926921 ChemDiv2_003611 Brc1ccc(cc1)c2nnc(SC(=O)OCc3ccccc3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E04 compound treatment 1059399.0 297000.0 0.63 884513.0 260000.0 0.59 0.8632 0.9995 1661495 ChemDiv2_003612 CC(C)CC(Nc1ncnc2ccc(C)cc12)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E05 compound treatment 1119645.0 357000.0 0.76 945135.0 320000.0 0.73 1.0509 0.9998 1027121 ChemDiv2_003613 Cc1nc(c([nH]1)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E06 compound treatment 1238234.0 476000.0 1.01 1090303.0 466000.0 1.06 1.4621 0.9997 1068433 ChemDiv2_003614 CC1C(N(C)C(CC1=O)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E07 compound treatment 974787.0 213000.0 0.45 917999.0 293000.0 0.67 0.7901 0.9818 1710211 ChemDiv2_003615 Cc1cc(C)nc(Nc2ccccc2O)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E08 compound treatment 1043970.0 282000.0 0.6 920286.0 296000.0 0.67 0.8975 0.9983 1293534 ChemDiv2_003616 OC(=O)CNc1ncnc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E09 compound treatment 1072084.0 310000.0 0.66 992792.0 368000.0 0.84 1.0562 0.9928 1448443 ChemDiv2_003617 CN(C)c1nc2n(C)c(=O)[nH]c(=O)c2n1Cc3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E10 compound treatment 1063952.0 302000.0 0.64 1000687.0 376000.0 0.85 1.0567 0.9898 1176262 ChemDiv2_003618 OC(CN1CCCCC1)Cn2c3CCCCc3c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E11 compound treatment 1156391.0 394000.0 0.84 1042585.0 418000.0 0.95 1.2627 0.998 1985489 ChemDiv2_003619 CCOc1ccc(OCCSc2nc3ccccc3n2CC(O)CO)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E12 compound treatment 1307441.0 545000.0 1.16 1713076.0 1090000.0 2.47 2.567 0.9399 1225379 ChemDiv2_003620 CCC(=O)Nc1nc2ccccc2n1CCN(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E13 compound treatment 1079374.0 317000.0 0.67 1484697.0 860000.0 1.96 1.858 0.8987 1985490 ChemDiv2_003621 Cc1nnc(SCC(=O)Nc2ccccn2)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E14 compound treatment 1289190.0 527000.0 1.12 1221728.0 597000.0 1.36 1.7497 0.9953 1624516 ChemDiv2_003622 O=C(Nc1nccs1)C2CC2(c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E15 compound treatment 1143792.0 382000.0 0.81 1129927.0 505000.0 1.15 1.3842 0.9853 1673253 ChemDiv2_003623 COc1ccc(NC(=O)CSc2nc3ccccc3o2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E16 compound treatment 1171617.0 409000.0 0.87 1019299.0 395000.0 0.9 1.2481 0.9999 1985491 ChemDiv2_003624 Nc1cccc(c1)c2nnc(o2)c3cccc(N)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E17 compound treatment 1084455.0 322000.0 0.68 1152644.0 528000.0 1.2 1.3318 0.9643 1286612 ChemDiv2_003625 O=C(Nc1c[nH]c(=O)[nH]c1=O)c2ccc3C(=O)N(C(=O)c3c2)c4ccc(cc4)C(=O)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E18 compound treatment 1240631.0 478000.0 1.01 1125323.0 501000.0 1.14 1.522 0.9984 1623041 ChemDiv2_003626 O=C(CN1C(=O)c2ccccc2C1=O)OCc3nc4ccccc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E19 compound treatment 1338066.0 576000.0 1.22 1024921.0 400000.0 0.91 1.5066 0.9895 1701518 ChemDiv2_003627 COc1ccc(cc1)c2cn3c(nc4ccccc43)n2CCN5CCN(CCO)CC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E20 compound treatment 1274060.0 512000.0 1.09 1063207.0 438000.0 1.0 1.4722 0.9991 1690451 ChemDiv2_003628 O=c1[nH]c2CCCc2c(=O)n1Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E21 compound treatment 1247435.0 485000.0 1.03 1106407.0 482000.0 1.1 1.5017 0.9995 1392568 ChemDiv2_003629 CCn1c2ccccc2c3nnc(SCC(=O)N4CCCc5ccccc45)nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E22 compound treatment 1253329.0 491000.0 1.04 902304.0 278000.0 0.63 1.1825 0.9712 1483513 ChemDiv2_003630 CNc1nc2ccccc2n1CCO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E23 mock treatment 1055383.0 293000.0 0.62 768012.0 143000.0 0.33 0.6698 0.9545 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 E24 mock treatment 857247.0 95100.0 0.2 529949.0 -94800.0 -0.22 -0.0099 -0.0335 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F01 compound treatment 685919.0 -76200.0 -0.16 654606.0 29800.0 0.07 -0.0663 -0.3784 1202698 ChemDiv2_003631 COc1ccc2ccccc2c1CN3CCN(CC3)C(=O)c4ccncc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F02 compound treatment 1034146.0 272000.0 0.58 933241.0 308000.0 0.7 0.9036 0.9953 1211430 ChemDiv2_003632 Cc1ccc2nsnc2c1NC(=O)C(c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F03 compound treatment 973439.0 211000.0 0.45 942101.0 317000.0 0.72 0.8269 0.9737 1196151 ChemDiv2_003633 Nc1nc(SCc2cnc(o2)c3ccccc3)nc4[nH]cnc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F04 compound treatment 943127.0 181000.0 0.38 994295.0 370000.0 0.84 0.8653 0.9369 1575799 ChemDiv2_003634 COC(=O)n1ccc(n1)C(=O)Nc2ccccc2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F05 compound treatment 1086558.0 324000.0 0.69 1018204.0 393000.0 0.89 1.1188 0.9916 1985492 ChemDiv2_003635 CC(C)Cc1ccc(cc1)C(C)C(=O)Nc2nccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F06 compound treatment 1069025.0 307000.0 0.65 1044103.0 419000.0 0.95 1.1341 0.9826 1565119 ChemDiv2_003636 CCC(Sc1nnc2c3ccccc3[nH]c2n1)C(=O)Nc4ccc(cc4)S(=O)(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F07 compound treatment 1131273.0 369000.0 0.78 1051490.0 427000.0 0.97 1.2393 0.9943 1518006 ChemDiv2_003637 COc1ccc(NC(=O)CSc2nc3ccccc3[nH]2)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F08 compound treatment 926655.0 165000.0 0.35 1072180.0 447000.0 1.02 0.9659 0.8982 1196538 ChemDiv2_003638 O=C(Nc1ccc2oc(nc2c1)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F09 compound treatment 1131746.0 370000.0 0.78 1221119.0 596000.0 1.36 1.5127 0.966 1616520 ChemDiv2_003639 COc1ccc(Nc2nc(nc3ccccc23)c4ccncc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F10 compound treatment 1169409.0 407000.0 0.86 1233670.0 609000.0 1.38 1.5894 0.9742 1409955 ChemDiv2_003640 O=C(Cc1ccccc1)Nc2cccc(c2)c3nc4ncccc4o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F11 compound treatment 1079323.0 317000.0 0.67 1518158.0 893000.0 2.03 1.9117 0.8935 1503587 ChemDiv2_003641 COc1cccc(c1)C(NC(=O)c2ccccc2)c3ccc4cccnc4c3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F12 compound treatment 1396016.0 634000.0 1.34 1833874.0 1210000.0 2.75 2.894 0.9458 1985493 ChemDiv2_003642 CCOC(=O)CSc1nc(N)c2c3CCCCc3sc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F13 compound treatment 1161333.0 399000.0 0.85 1423322.0 799000.0 1.82 1.8822 0.9396 1654439 ChemDiv2_003643 CCOC(=O)c1c(NC(=O)C)sc2c(OCC(O)CNC(C)(C)C)c(Br)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F14 compound treatment 1131988.0 370000.0 0.78 1667795.0 1040000.0 2.37 2.2312 0.8933 1863043 ChemDiv2_003644 COc1ccc(cc1NC(=O)C)c2nc3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F15 compound treatment 1187746.0 426000.0 0.9 1215730.0 591000.0 1.34 1.588 0.9812 1295749 ChemDiv2_003645 Nc1nnc(SCC(=O)n2c3ccccc3c4ccccc24)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F16 compound treatment 1061239.0 299000.0 0.63 1305872.0 681000.0 1.55 1.5433 0.9223 1443603 ChemDiv2_003646 CCCCC1CC(CSc2nnc[nH]2)OC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F17 compound treatment 1219637.0 457000.0 0.97 1187500.0 563000.0 1.28 1.5904 0.9907 1985494 ChemDiv2_003647 CCCCC(=O)Nc1cccc2nsnc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F18 compound treatment 1270385.0 508000.0 1.08 1259085.0 634000.0 1.44 1.7816 0.9897 1417832 ChemDiv2_003648 CCOC(=O)c1sc2nc(CC(=O)OC)nc(NCC(=O)OC)c2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F19 compound treatment 1080539.0 318000.0 0.67 1059938.0 435000.0 0.99 1.1769 0.9826 1673558 ChemDiv2_003649 CC(C)OC(=O)c1c(C)oc2ccc(OC(=O)N3CCOCC3)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F20 compound treatment 1072378.0 310000.0 0.66 996245.0 371000.0 0.84 1.0622 0.9923 1452684 ChemDiv2_003650 CCc1nc2ccccc2n1CC(O)COc3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F21 compound treatment 1010246.0 248000.0 0.53 1070299.0 446000.0 1.01 1.0881 0.9534 1392118 ChemDiv2_003651 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3CCN(CC3)c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F22 compound treatment 1089610.0 327000.0 0.69 978897.0 354000.0 0.81 1.0602 0.9973 1270735 ChemDiv2_003652 Cn1c(=O)n(C)c2nc(Oc3ccc4OCOc4c3)n(Cc5ccc(F)cc5)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F23 mock treatment 821731.0 59600.0 0.13 875009.0 250000.0 0.57 0.4916 0.8435 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 F24 mock treatment 683258.0 -78900.0 -0.17 577479.0 -47300.0 -0.11 -0.1943 -0.9772 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G01 compound treatment 758906.0 -3250.0 -0.01 709629.0 84900.0 0.19 0.1316 0.6814 1157550 ChemDiv2_003653 C=CCn1c(NCc2ccc3OCOc3c2)nc4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G02 compound treatment 923250.0 161000.0 0.34 857886.0 233000.0 0.53 0.6163 0.9774 1944148 ChemDiv2_003654 Cc1nnc(SCc2ccc(cc2)C(=O)O)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G03 compound treatment 989651.0 227000.0 0.48 814535.0 190000.0 0.43 0.6461 0.9985 1318133 ChemDiv2_003655 Fc1ccccc1C(=O)Nc2ccccc2c3nc4ccccc4[nH]3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G04 compound treatment 1012817.0 251000.0 0.53 905783.0 281000.0 0.64 0.8275 0.9958 1985495 ChemDiv2_003656 CCC(Sc1nc2ccccc2s1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G05 compound treatment 946205.0 184000.0 0.39 984602.0 360000.0 0.82 0.8544 0.9426 1919506 ChemDiv2_003657 CSc1nc2c(ccc3ccccc23)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G06 compound treatment 1249501.0 487000.0 1.03 991932.0 367000.0 0.83 1.3208 0.9944 1571661 ChemDiv2_003658 OC(=O)CSc1nc(c([nH]1)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G07 compound treatment 1131550.0 369000.0 0.78 1088460.0 464000.0 1.05 1.2992 0.9893 1092526 ChemDiv2_003659 c1cn2cc(nc2s1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G08 compound treatment 1154015.0 392000.0 0.83 1006146.0 381000.0 0.87 1.2005 0.9998 1985496 ChemDiv2_003660 Cc1n[nH]c(C)c1Sc2n[nH]c(=O)[nH]c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G09 compound treatment 1241800.0 480000.0 1.02 1210802.0 586000.0 1.33 1.6611 0.9911 1651780 ChemDiv2_003661 Cc1ccc(Cn2c(SCC(O)CO)nc3n(C)c(=O)[nH]c(=O)c23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G10 compound treatment 1088620.0 326000.0 0.69 1406834.0 782000.0 1.78 1.7467 0.9154 1328756 ChemDiv2_003662 Nc1nc2ccccc2n1CCN3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G11 compound treatment 1210961.0 449000.0 0.95 1628507.0 1000000.0 2.28 2.2864 0.9248 1416633 ChemDiv2_003663 CCOC(=O)N1CCN(CC1)C(=O)CC(c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G12 compound treatment 1208652.0 446000.0 0.95 1640337.0 1020000.0 2.31 2.302 0.9225 1677178 ChemDiv2_003664 CCN(CC)CCn1c(NC(=O)CC)nc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G13 compound treatment 991888.0 230000.0 0.49 1639860.0 1020000.0 2.31 1.9763 0.8379 1260672 ChemDiv2_003665 CCOC(=O)Cc1csc(NC(=O)COc2c(C)cccc2C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G14 compound treatment 1315473.0 553000.0 1.17 1493319.0 869000.0 1.97 2.2258 0.9691 1985497 ChemDiv2_003666 Cc1nn(c2ccc(Cl)cc2Cl)c(=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G15 compound treatment 1068324.0 306000.0 0.65 1621379.0 997000.0 2.27 2.0611 0.8745 1373053 ChemDiv2_003667 NS(=O)(=O)c1ccc(NC(=O)CSc2ccccn2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G16 compound treatment 1435966.0 674000.0 1.43 1560269.0 935000.0 2.13 2.514 0.9812 1211062 ChemDiv2_003668 CC(=O)Oc1cccc(c1)c2nc3ccccc3c(=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G17 compound treatment 1489895.0 728000.0 1.54 1234225.0 609000.0 1.39 2.0707 0.9986 1480638 ChemDiv2_003669 O=C(Nc1c[nH]c(=O)[nH]c1=O)C(c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G18 compound treatment 1331246.0 569000.0 1.21 1119459.0 495000.0 1.12 1.6484 0.9994 1638448 ChemDiv2_003670 O=C(Nc1nc(cs1)c2ccc3OCOc3c2)c4cc5ccccc5oc4=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G19 compound treatment 1260562.0 498000.0 1.06 1094487.0 470000.0 1.07 1.5023 1.0 1985498 ChemDiv2_003671 Cc1noc(n1)c2ccccc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G20 compound treatment 1206142.0 444000.0 0.94 961290.0 337000.0 0.77 1.2066 0.9947 1269795 ChemDiv2_003672 O=C(Nc1cccc(c1)c2nc3ccccc3o2)c4cc(=O)c5ccccc5o4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G21 compound treatment 1055795.0 294000.0 0.62 1033385.0 409000.0 0.93 1.0971 0.981 1985499 ChemDiv2_003673 CCC1C(=O)NC(=NC1=O)SCC(=O)NCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G22 compound treatment 1183934.0 422000.0 0.89 825375.0 201000.0 0.46 0.9548 0.9512 1328542 ChemDiv2_003674 O=C(NCC1COc2ccccc2O1)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G23 mock treatment 1114228.0 352000.0 0.75 842837.0 218000.0 0.5 0.8783 0.9802 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 G24 mock treatment 576913.0 -185000.0 -0.39 547244.0 -77500.0 -0.18 -0.4023 -0.9347 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H01 compound treatment 767516.0 5360.0 0.01 780821.0 156000.0 0.35 0.2589 0.7294 1985500 ChemDiv2_003675 C(Cc1c[nH]c2ccccc12)NCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H02 compound treatment 864394.0 102000.0 0.22 905338.0 281000.0 0.64 0.6043 0.897 1985501 ChemDiv2_003676 O=C(CSc1ccccn1)Nc2ccc(cc2)c3ccc(NC(=O)CSc4ccccn4)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H03 compound treatment 978672.0 217000.0 0.46 1094728.0 470000.0 1.07 1.0801 0.9288 1985502 ChemDiv2_003677 O=C(OCc1cnc(o1)c2ccccc2)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H04 compound treatment 990248.0 228000.0 0.48 1218386.0 594000.0 1.35 1.2962 0.9042 1412880 ChemDiv2_003678 C(Nc1ncnc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H05 compound treatment 1083536.0 321000.0 0.68 1030187.0 405000.0 0.92 1.1335 0.9889 1228522 ChemDiv2_003679 CSc1nc2sc3CCCCc3c2c(=O)n1CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H06 compound treatment 1173308.0 411000.0 0.87 1254608.0 630000.0 1.43 1.6289 0.9717 1249130 ChemDiv2_003680 CCCn1c2ccccc2c3nnc(SCOC(=O)CN4C(=O)c5ccccc5C4=O)nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H07 compound treatment 1103623.0 341000.0 0.72 1366984.0 742000.0 1.69 1.7051 0.9286 1660833 ChemDiv2_003681 COC(=O)COc1ccc2c(=O)c(coc2c1)c3ccccc3OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H08 compound treatment 1239395.0 477000.0 1.01 1567838.0 943000.0 2.14 2.2315 0.9412 1677022 ChemDiv2_003682 O=C(COc1ccccc1)Nc2ccc(cc2)c3nc4ncccc4o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H09 compound treatment 1360344.0 598000.0 1.27 2009089.0 1380000.0 3.15 3.1222 0.9201 1160263 ChemDiv2_003683 C1CCC(CC1)Nc2nc(nc3ccccc23)c4ccncc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H10 compound treatment 1481725.0 720000.0 1.53 2046467.0 1420000.0 3.23 3.3642 0.9413 1599171 ChemDiv2_003684 O=C1CCCC2=C1C(Nc3ccccc3N2)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H11 compound treatment 1449094.0 687000.0 1.46 2096937.0 1470000.0 3.35 3.3965 0.9305 1221016 ChemDiv2_003685 COc1ccc(cc1)C(NC(=O)c2ccccc2)c3ccc4cccnc4c3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H12 compound treatment 1610657.0 849000.0 1.8 2542612.0 1920000.0 4.36 4.3551 0.9233 1384204 ChemDiv2_003686 O=C(CN1C(=O)c2ccccc2C1=O)N3c4ccccc4CCc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H13 compound treatment 1635228.0 873000.0 1.85 1669872.0 1050000.0 2.38 2.9889 0.9924 1514352 ChemDiv2_003687 CCCN1C(=O)C(Cc2nc3ccccc3c(=O)n2C)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H14 compound treatment 1633405.0 871000.0 1.85 1714697.0 1090000.0 2.48 3.0582 0.9895 1651359 ChemDiv2_003688 O=C1C2C3CC(C=C3)C2C(=O)N1CCc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H15 compound treatment 1404265.0 642000.0 1.36 1724850.0 1100000.0 2.5 2.7311 0.9591 1312208 ChemDiv2_003689 Nc1nnc(SCC(=O)N2CCc3ccccc3C2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H16 compound treatment 1411771.0 650000.0 1.38 1722216.0 1100000.0 2.5 2.7381 0.9608 1350114 ChemDiv2_003690 CN(C)c1ccc(cc1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H17 compound treatment 1372249.0 610000.0 1.29 1754030.0 1130000.0 2.57 2.73 0.9496 1523430 ChemDiv2_003691 CC1(C)Cc2ccccc2C(=N1)CSc3ccccc3C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H18 compound treatment 1594081.0 832000.0 1.76 1388552.0 764000.0 1.74 2.475 1.0 1447449 ChemDiv2_003692 CCCCN(CC)C(=O)c1sc2ncn(CC(=O)N(CC)CC)c(=O)c2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H19 compound treatment 1701306.0 939000.0 1.99 1060790.0 436000.0 0.99 2.1088 0.9482 1171480 ChemDiv2_003693 CC(=C)COc1ccc2oc(c(C(=O)O)c2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H20 compound treatment 1184996.0 423000.0 0.9 859059.0 234000.0 0.53 1.0105 0.9691 1302163 ChemDiv2_003694 OC(=O)CNc1nc(c2ccccc2)c3cc(Br)ccc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H21 compound treatment 1205575.0 443000.0 0.94 842791.0 218000.0 0.5 1.0152 0.9553 1648808 ChemDiv2_003695 Cn1c(=O)n(C)c2ncn(Cc3ccc(F)cc3)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H22 compound treatment 1059925.0 298000.0 0.63 861067.0 236000.0 0.54 0.8262 0.9968 1985503 ChemDiv2_003696 CCCOc1cccc(c1)C(=O)Nc2c[nH]c(=O)[nH]c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H23 mock treatment 1065334.0 303000.0 0.64 813642.0 189000.0 0.43 0.7581 0.9808 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 H24 mock treatment 610972.0 -151000.0 -0.32 462931.0 -162000.0 -0.37 -0.4868 -0.9976 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I01 compound treatment 937921.0 176000.0 0.37 758723.0 134000.0 0.3 0.4788 0.995 1310171 ChemDiv2_003697 Cn1c(CNc2ccc(cc2)C(=O)O)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I02 compound treatment 1163293.0 401000.0 0.85 990974.0 366000.0 0.83 1.19 0.9999 1402934 ChemDiv2_003698 COc1ccc2[nH]c(SCC(=O)c3ccc4OCOc4c3)nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I03 compound treatment 1095548.0 333000.0 0.71 1087471.0 463000.0 1.05 1.2436 0.9813 1985504 ChemDiv2_003699 CC(=C)c1nc2ccccc2c(=O)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I04 compound treatment 1243093.0 481000.0 1.02 1190070.0 565000.0 1.29 1.6297 0.9934 1246016 ChemDiv2_003700 CCN(CC)C(=O)c1sc2nc(C)cc(C)c2c1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I05 compound treatment 1194570.0 432000.0 0.92 1101982.0 477000.0 1.08 1.4154 0.9965 1985505 ChemDiv2_003701 COc1nnc(Cl)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I06 compound treatment 1425133.0 663000.0 1.41 1023707.0 399000.0 0.91 1.6352 0.9775 1985506 ChemDiv2_003702 CCOc1ccc(Nc2nc(Cl)nc(NCC=C)n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I07 compound treatment 1362473.0 600000.0 1.27 1266569.0 642000.0 1.46 1.9317 0.9977 1594743 ChemDiv2_003703 Cn1c(NCC=C)nc2n(C)c(=O)[nH]c(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I08 compound treatment 1436151.0 674000.0 1.43 1259638.0 635000.0 1.44 2.031 1.0 1985507 ChemDiv2_003704 Cn1c(=O)n(C)c2nc(NCC3CCCO3)n(Cc4ccc(Cl)cc4)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I09 compound treatment 1300111.0 538000.0 1.14 1332446.0 708000.0 1.61 1.9441 0.9858 1945711 ChemDiv2_003705 CCN(CC)CCSc1nc(O)c(CC)c(=O)n1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I10 compound treatment 1740626.0 978000.0 2.07 1393068.0 768000.0 1.75 2.7019 0.9963 1217164 ChemDiv2_003706 Nc1nc2ccccc2n1CCN3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I11 compound treatment 1549656.0 788000.0 1.67 1467519.0 843000.0 1.92 2.5353 0.9976 1306044 ChemDiv2_003707 OCCN1C(=O)c2ccccc2C1(O)c3ncc[nH]3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I12 compound treatment 1837289.0 1080000.0 2.28 1375594.0 751000.0 1.71 2.8187 0.9899 1517877 ChemDiv2_003708 Cc1ccc(Cn2c(NC(=O)c3cccs3)nc4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I13 compound treatment 1371872.0 610000.0 1.29 1313650.0 689000.0 1.57 2.0215 0.9955 1405523 ChemDiv2_003709 CC(C)N(Cc1c(O)ccc2c(=O)c(coc12)c3ccccc3)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I14 compound treatment 1476877.0 715000.0 1.52 1643989.0 1020000.0 2.32 2.7099 0.9788 1674829 ChemDiv2_003710 CN(C)C(=O)Cn1nc(C)c2ccccc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I15 compound treatment 1502198.0 740000.0 1.57 1744464.0 1120000.0 2.55 2.9094 0.973 1592972 ChemDiv2_003711 CSc1nc2ccccc2n1CCOc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I16 compound treatment 1537828.0 776000.0 1.64 1520400.0 896000.0 2.04 2.6026 0.9944 1985508 ChemDiv2_003712 C=CCn1c2ncnn2c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I17 compound treatment 1617826.0 856000.0 1.81 1301801.0 677000.0 1.54 2.3711 0.9967 1341879 ChemDiv2_003713 O=C(Cc1ccccc1)Nc2c[nH]c(=O)[nH]c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I18 compound treatment 1683452.0 921000.0 1.95 1133720.0 509000.0 1.16 2.1993 0.9688 1260052 ChemDiv2_003714 CC1CCN(CC1)S(=O)(=O)c2ccc3NC(=O)c4cccc2c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I19 compound treatment 1379019.0 617000.0 1.31 1077518.0 453000.0 1.03 1.6526 0.993 1610987 ChemDiv2_003715 COC(=O)c1ccc(cc1)n2c(C)nc3ccccc3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I20 compound treatment 1306601.0 544000.0 1.15 969486.0 345000.0 0.78 1.3703 0.9822 1662741 ChemDiv2_003716 CCOC(=O)c1sc2ccccc2c1NC(=O)c3coc4ccccc4c3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I21 compound treatment 1369110.0 607000.0 1.29 1017237.0 392000.0 0.89 1.5408 0.984 1030466 ChemDiv2_003717 CCN(CC)CCSc1nc2ccccc2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I22 compound treatment 1404038.0 642000.0 1.36 930793.0 306000.0 0.7 1.4542 0.9515 1598232 ChemDiv2_003718 OCCNc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)n1c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I23 mock treatment 1095239.0 333000.0 0.71 890304.0 266000.0 0.6 0.9262 0.997 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 I24 mock treatment 651178.0 -111000.0 -0.24 635182.0 10400.0 0.02 -0.1496 -0.6328 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J01 compound treatment 835773.0 73600.0 0.16 552982.0 -71800.0 -0.16 -0.0051 -0.0224 1586604 ChemDiv2_003719 CC(C)NCCc1c[nH]c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J02 compound treatment 922696.0 161000.0 0.34 860530.0 236000.0 0.54 0.6197 0.976 1646746 ChemDiv2_003720 Oc1ccc(cc1)n2c(nc3ccccc3c2=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J03 compound treatment 1046544.0 284000.0 0.6 960852.0 336000.0 0.76 0.9666 0.9931 1985509 ChemDiv2_003721 CCC1C(=O)NC(=NC1=O)SCC(=O)Nc2ncccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J04 compound treatment 1049921.0 288000.0 0.61 1066235.0 441000.0 1.0 1.1411 0.9715 1509059 ChemDiv2_003722 Cc1cccc(NC(=O)Cn2cnc3ccccc3c2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J05 compound treatment 1169503.0 407000.0 0.86 1037900.0 413000.0 0.94 1.2748 0.9991 1500678 ChemDiv2_003723 O=C(CSc1nc2ccccc2o1)NC(=O)CSc3nc4ccccc4o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J06 compound treatment 1539609.0 777000.0 1.65 1032371.0 408000.0 0.93 1.8207 0.9629 1579030 ChemDiv2_003724 C(CN1CCOCC1)Sc2nnc3c4ccccc4n(CCc5ccccc5)c3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J07 compound treatment 972275.0 210000.0 0.45 1138646.0 514000.0 1.17 1.1411 0.9126 1285901 ChemDiv2_003725 CCN(CC)Cc1c(O)ccc2c(cc(=O)oc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J08 compound treatment 1352725.0 591000.0 1.25 1173096.0 548000.0 1.25 1.7668 1.0 1722301 ChemDiv2_003726 OC(=O)CCSc1nc2ccccc2n1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J09 compound treatment 1508378.0 746000.0 1.58 1077732.0 453000.0 1.03 1.8468 0.9784 1985510 ChemDiv2_003727 COc1nc(nc2ccccc12)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J10 compound treatment 1794458.0 1030000.0 2.19 1307549.0 683000.0 1.55 2.6451 0.9858 1256759 ChemDiv2_003728 CCC(=O)N1C(C2=C(CCCC2=O)Nc3ccccc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J11 compound treatment 1731300.0 969000.0 2.05 1412000.0 787000.0 1.79 2.7184 0.9976 1544625 ChemDiv2_003729 COc1ccc(cc1OC)C(NC(=O)C(C)C)c2ccc3cccnc3c2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J12 compound treatment 1011469.0 249000.0 0.53 1562789.0 938000.0 2.13 1.8817 0.8564 1471874 ChemDiv2_003730 CC1=CC(C)(C)Nc2ccc(OC(=O)CN3C(=O)CCC3=O)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J13 compound treatment 1159094.0 397000.0 0.84 1252567.0 628000.0 1.43 1.6043 0.9682 1274056 ChemDiv2_003731 CC(C)Cc1cc(c2ccco2)c(C#N)c(NC(=O)C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J14 compound treatment 1853940.0 1090000.0 2.31 1283006.0 658000.0 1.5 2.6948 0.9777 1642129 ChemDiv2_003732 CC1(C)CC(=O)C2=C(C1)c3c(NC2c4ccncc4)ccc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J15 compound treatment 1572139.0 810000.0 1.72 1355567.0 731000.0 1.66 2.3891 0.9999 1261161 ChemDiv2_003733 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4ccco4)C(=O)C5CC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J16 compound treatment 1728098.0 966000.0 2.05 1270031.0 645000.0 1.47 2.4853 0.9866 1402608 ChemDiv2_003734 CC(=O)NCC1OCCc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J17 compound treatment 1753758.0 992000.0 2.1 1211774.0 587000.0 1.33 2.4301 0.976 1287279 ChemDiv2_003735 COc1cc2CC3(CCCC3)n4c(C)nnc4-c2cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J18 compound treatment 1544103.0 782000.0 1.66 1167397.0 543000.0 1.23 2.0445 0.9894 1284539 ChemDiv2_003736 Cc1sc2ncn(CC(=O)NCC(=O)O)c(=O)c2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J19 compound treatment 1338777.0 577000.0 1.22 1000726.0 376000.0 0.85 1.4688 0.9847 1386115 ChemDiv2_003737 CCOC(=O)COc1ccc2cc(c3nc4ccccc4[nH]3)c(=O)oc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J20 compound treatment 1340170.0 578000.0 1.23 992144.0 367000.0 0.84 1.4571 0.9825 1606578 ChemDiv2_003738 COc1ccc(NC(=O)CCSc2nc3ccccc3s2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J21 compound treatment 1196178.0 434000.0 0.92 969513.0 345000.0 0.78 1.2048 0.9968 1449803 ChemDiv2_003739 Cc1ccc2n3CCN(CCC#N)C4CCCc(c43)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J22 compound treatment 1178060.0 416000.0 0.88 870284.0 246000.0 0.56 1.0182 0.9757 1781477 ChemDiv2_003740 OC(=O)c1ccccc1c2ccccc2C(=O)Nc3c[nH]c(=O)[nH]c3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J23 mock treatment 1190042.0 428000.0 0.91 658291.0 33500.0 0.08 0.6953 0.7638 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 J24 mock treatment 632428.0 -130000.0 -0.28 568309.0 -56500.0 -0.13 -0.2852 -0.9398 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K01 compound treatment 711522.0 -50600.0 -0.11 684433.0 59700.0 0.14 0.02 0.1157 1985511 ChemDiv2_003741 CN(C(=O)c1nc[nH]n1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K02 compound treatment 1125765.0 364000.0 0.77 967792.0 343000.0 0.78 1.0965 1.0 1391868 ChemDiv2_003742 COc1cc(CNc2nc3ccccc3[nH]2)cc(OC)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K03 compound treatment 1141388.0 379000.0 0.8 1006871.0 382000.0 0.87 1.1828 0.9993 1280356 ChemDiv2_003743 CCCOc1ccc(cc1)c2nc(N)n[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K04 compound treatment 1384560.0 622000.0 1.32 1142574.0 518000.0 1.18 1.7654 0.9984 1985512 ChemDiv2_003744 COC(=O)C1=C(N)OC2=C(C1c3cccnc3)C(=O)CCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K05 compound treatment 1249847.0 488000.0 1.03 980620.0 356000.0 0.81 1.3031 0.9926 1166877 ChemDiv2_003745 CSc1nsc(SC)c1NC(=O)OC2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K06 compound treatment 1441874.0 680000.0 1.44 969502.0 345000.0 0.78 1.5731 0.959 1505337 ChemDiv2_003746 CS(=O)(=O)N1CCN(CC(O)Cn2c3ccccc3c4ccccc24)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K07 compound treatment 1291052.0 529000.0 1.12 1041743.0 417000.0 0.95 1.4632 0.9965 1402712 ChemDiv2_003747 CCn1c(nc2n(C)c(=O)[nH]c(=O)c12)N3CCCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K08 compound treatment 1431335.0 669000.0 1.42 972356.0 348000.0 0.79 1.5619 0.9618 1569509 ChemDiv2_003748 Cn1c(=O)n(C)c2nc(NC3CCCCC3)n(Cc4ccccc4F)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K09 compound treatment 1232815.0 471000.0 1.0 1133496.0 509000.0 1.16 1.5234 0.9973 1783822 ChemDiv2_003749 CCN(CC)CCSc1nc(O)c(C2CCCCC2)c(=O)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K10 compound treatment 1492838.0 731000.0 1.55 1043280.0 419000.0 0.95 1.7681 0.9726 1601163 ChemDiv2_003750 Cn1c(=N)n(CC(O)c2ccccc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K11 compound treatment 1521084.0 759000.0 1.61 1242876.0 618000.0 1.41 2.1314 0.9977 1428781 ChemDiv2_003751 C(Sc1nnc2c3ccccc3[nH]c2n1)C4COc5ccccc5O4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K12 compound treatment 1600756.0 839000.0 1.78 1258641.0 634000.0 1.44 2.2761 0.9946 1587696 ChemDiv2_003752 CCc1ccc(cc1)c2cn3c(nc4ccccc43)n2CCO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K13 compound treatment 1679469.0 917000.0 1.94 982070.0 357000.0 0.81 1.9495 0.925 1525172 ChemDiv2_003753 CCN(CC)Cc1c(O)ccc2c(=O)c(coc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K14 compound treatment 1802004.0 1040000.0 2.2 1244705.0 620000.0 1.41 2.5554 0.9766 1590784 ChemDiv2_003754 Oc1ccc(NC(=O)Cn2nc(c3ccccc3)c4ccccc4c2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K15 compound treatment 1245544.0 483000.0 1.02 1223712.0 599000.0 1.36 1.6875 0.9902 1316920 ChemDiv2_003755 CCOC(=O)c1c(CN(CC)CC)n(C)c2cc(Br)c(OC)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K16 compound treatment 1323535.0 561000.0 1.19 1081414.0 457000.0 1.04 1.5756 0.9977 1985513 ChemDiv2_003756 Cn1c(NC(=N)c2ccccc2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K17 compound treatment 1371636.0 609000.0 1.29 1004005.0 379000.0 0.86 1.5233 0.9807 1660106 ChemDiv2_003757 O=C(Nc1nccs1)c2ccc3C(=O)N(CC4CCCO4)C(=O)c3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K18 compound treatment 1528548.0 766000.0 1.62 952329.0 328000.0 0.74 1.6754 0.9374 1448867 ChemDiv2_003758 Cc1nc2c(ccc3nc(NC(=O)c4ccc(cc4)N5C(=O)CCC5=O)sc32)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K19 compound treatment 1379523.0 617000.0 1.31 923414.0 299000.0 0.68 1.4056 0.9533 1985514 ChemDiv2_003759 COc1nc(NC(=O)C)nc(C)c1Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K20 compound treatment 1304330.0 542000.0 1.15 911632.0 287000.0 0.65 1.2739 0.964 1661172 ChemDiv2_003760 Cn1c(=O)n(C)c2nc(NCCO)n(Cc3ccc(F)cc3)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K21 compound treatment 1058920.0 297000.0 0.63 955880.0 331000.0 0.75 0.9772 0.996 1249651 ChemDiv2_003761 Cc1ccc(cc1NC(=O)c2ccc3OCCOc3c2)c4nc5ccccc5s4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K22 compound treatment 1076530.0 314000.0 0.67 868291.0 244000.0 0.55 0.8628 0.9958 1985515 ChemDiv2_003762 COC(=O)C(C)N(C#N)c1nc(C)cc(C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K23 mock treatment 904034.0 142000.0 0.3 783170.0 158000.0 0.36 0.4673 0.996 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 K24 mock treatment 594178.0 -168000.0 -0.36 469365.0 -155000.0 -0.35 -0.5016 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L01 compound treatment 579703.0 -182000.0 -0.39 533803.0 -91000.0 -0.21 -0.4197 -0.957 1525834 ChemDiv2_003763 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3c4ccccc4Sc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L02 compound treatment 703858.0 -58300.0 -0.12 1026414.0 402000.0 0.91 0.5583 0.6059 1372259 ChemDiv2_003764 Oc1cccc(c1)n2c(nc3ccccc3c2=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L03 compound treatment 897015.0 135000.0 0.29 1036540.0 412000.0 0.94 0.8641 0.8828 1119977 ChemDiv2_003765 Cc1nn(c2cccc(c2)C(=O)O)c(=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L04 compound treatment 945574.0 183000.0 0.39 1096448.0 472000.0 1.07 1.0332 0.9058 1682266 ChemDiv2_003766 O=C(CN1C(=O)c2ccccc2C1=O)N3CCc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L05 compound treatment 996368.0 234000.0 0.5 1018019.0 393000.0 0.89 0.9833 0.9615 1695161 ChemDiv2_003767 Cn1c(SCC(=O)Nc2ccccc2Oc3ccccc3)nc4ccccc4c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L06 compound treatment 898574.0 136000.0 0.29 921421.0 297000.0 0.67 0.6814 0.9286 1668224 ChemDiv2_003768 C(NC(Cc1ccccc1)c2ccccc2)c3c[nH]c4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L07 compound treatment 1009921.0 248000.0 0.53 1052682.0 428000.0 0.97 1.0593 0.9581 1332500 ChemDiv2_003769 CCCCN(C)Cc1c(O)ccc2c(=O)c(coc12)c3ccccc3OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L08 compound treatment 1000915.0 239000.0 0.51 1044483.0 420000.0 0.95 1.0327 0.956 1577473 ChemDiv2_003770 COc1ccc(NC(=O)Cn2c(nc3ccccc23)c4cscn4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L09 compound treatment 1179558.0 417000.0 0.88 1111137.0 486000.0 1.11 1.4076 0.9939 1932196 ChemDiv2_003771 CCn1c(SCC(=O)c2ccccc2)nc3ccccc3c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L10 compound treatment 1192743.0 431000.0 0.91 1112680.0 488000.0 1.11 1.4298 0.9953 1190368 ChemDiv2_003772 O=C(N1C(C2=C(CCCC2=O)Nc3ccccc13)c4ccco4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L11 compound treatment 1114186.0 352000.0 0.75 1383925.0 759000.0 1.73 1.7482 0.9297 1173633 ChemDiv2_003773 Oc1c(ccc2cccnc12)C(NC(=O)c3ccccc3)c4ccccc4Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L12 compound treatment 1200807.0 439000.0 0.93 1462637.0 838000.0 1.9 2.0045 0.9456 1619780 ChemDiv2_003774 CC1(C)CC(=O)C2=C(C1)N=C3C(C2c4ccc(O)c(O)c4)C(=O)c5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L13 compound treatment 1116872.0 355000.0 0.75 1425329.0 801000.0 1.82 1.8187 0.9235 1668288 ChemDiv2_003775 CCOC(=O)C(C1CCCCC1)C(=O)Nc2nc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L14 compound treatment 1506773.0 745000.0 1.58 1403767.0 779000.0 1.77 2.3686 0.9984 1207293 ChemDiv2_003776 CC(C)(C)C1CCC(CC1)OC(=O)CCC(=O)Nc2nccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L15 compound treatment 1082073.0 320000.0 0.68 1018907.0 394000.0 0.9 1.1132 0.9906 1985516 ChemDiv2_003777 COC(=O)C1=CNC=C(C1c2ccc(C)s2)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L16 compound treatment 1245586.0 483000.0 1.02 1023275.0 399000.0 0.91 1.3653 0.9981 1154571 ChemDiv2_003778 CNC(=O)CC1Sc2ccccc2NC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L17 compound treatment 1238250.0 476000.0 1.01 1130970.0 506000.0 1.15 1.5275 0.9979 1605114 ChemDiv2_003779 C1CCC2(CC1)Cc3ccccc3-c4nnc(c5cccnc5)n42 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L18 compound treatment 1293937.0 532000.0 1.13 1113634.0 489000.0 1.11 1.5831 1.0 1728037 ChemDiv2_003780 CCOC(=O)c1sc2ncnc(N3CCc4ccccc4C3)c2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L19 compound treatment 1182631.0 420000.0 0.89 922609.0 298000.0 0.68 1.1091 0.9908 1134290 ChemDiv2_003781 CC1CCCN(Cc2c(O)ccc3c(=O)c(c4nc5ccccc5s4)c(C)oc23)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L20 compound treatment 1113553.0 351000.0 0.74 1109133.0 484000.0 1.1 1.3054 0.9819 1285086 ChemDiv2_003782 CN(C)Cc1c(O)ccc2c(=O)c(coc12)c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L21 compound treatment 989575.0 227000.0 0.48 930306.0 306000.0 0.69 0.8321 0.9841 1116168 ChemDiv2_003783 Cn1c(=O)n(C)c2ncn(CC=C)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L22 compound treatment 1082778.0 321000.0 0.68 905702.0 281000.0 0.64 0.9323 0.9995 1522786 ChemDiv2_003784 O=C1CCC(=O)N1c2ccc(cc2)c3nc4ccccc4c(=O)o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L23 mock treatment 786967.0 24800.0 0.05 775720.0 151000.0 0.34 0.2799 0.8061 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 L24 mock treatment 506629.0 -256000.0 -0.54 537462.0 -87300.0 -0.2 -0.5234 -0.9072 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M01 compound treatment 517477.0 -245000.0 -0.52 696666.0 71900.0 0.16 -0.2512 -0.4619 1247577 ChemDiv2_003785 O=C(COc1ccc2c(=O)c(coc2c1)c3ccccc3)N4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M02 compound treatment 832284.0 70100.0 0.15 969212.0 344000.0 0.78 0.6589 0.8266 1274952 ChemDiv2_003786 O=C1N(Cc2nc3ccccc3c(=O)n2c4ccncc4)C(=O)c5ccccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M03 compound treatment 787405.0 25300.0 0.05 1040323.0 416000.0 0.94 0.7059 0.746 1652071 ChemDiv2_003787 Clc1ccc(OC(C(=O)c2ccc(Cl)cc2)n3cncn3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M04 compound treatment 881497.0 119000.0 0.25 1016238.0 391000.0 0.89 0.8082 0.8735 1611104 ChemDiv2_003788 Cn1c(=O)n(C)c2ncn(CC(=O)Nc3ccc(C#N)c(Cl)c3)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M05 compound treatment 1074287.0 312000.0 0.66 960367.0 336000.0 0.76 1.0074 0.9975 1261321 ChemDiv2_003789 COc1ccc(Cl)cc1S(=O)(=O)n2ccnc2C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M06 compound treatment 1053055.0 291000.0 0.62 909054.0 284000.0 0.65 0.8931 0.9997 1507411 ChemDiv2_003790 CS(=O)(=O)N(CC(O)Cn1c2ccccc2c3ccccc13)Cc4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M07 compound treatment 959502.0 197000.0 0.42 1064578.0 440000.0 1.0 1.0029 0.9252 1708969 ChemDiv2_003791 Cn1c(SCC(=O)c2ccccc2)nc3n(C)c(=O)[nH]c(=O)c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M08 compound treatment 888240.0 126000.0 0.27 949363.0 325000.0 0.74 0.7108 0.9056 1362523 ChemDiv2_003792 CC(CCO)Nc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccccc3Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M09 compound treatment 1165539.0 403000.0 0.86 1125487.0 501000.0 1.14 1.4097 0.9901 1560195 ChemDiv2_003793 CN(C)CCSc1nc(O)c(c2ccccc2)c(=O)n1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M10 compound treatment 944114.0 182000.0 0.39 979281.0 355000.0 0.81 0.8427 0.9431 1738517 ChemDiv2_003794 CC(O)Cn1c(=N)n(Cc2ccccc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M11 compound treatment 1028829.0 267000.0 0.57 963705.0 339000.0 0.77 0.9446 0.9884 1485737 ChemDiv2_003795 C(CN1CCCCC1)Sc2nnc3c4ccccc4[nH]c3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M12 compound treatment 1244166.0 482000.0 1.02 1159039.0 534000.0 1.21 1.5815 0.9963 1174008 ChemDiv2_003796 O=S(=O)(Cc1ccccc1)c2nc3ccccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M13 compound treatment 1091745.0 330000.0 0.7 988253.0 363000.0 0.83 1.0784 0.9965 1673829 ChemDiv2_003797 CN(C)Cc1c(O)ccc2c(=O)c(coc12)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M14 compound treatment 992278.0 230000.0 0.49 1036824.0 412000.0 0.94 1.0074 0.9538 1524792 ChemDiv2_003798 OC(=O)CCC(=O)Nc1ccc(cc1)c2nc3cc(NC(=O)CCC(=O)O)ccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M15 compound treatment 1059239.0 297000.0 0.63 996986.0 372000.0 0.85 1.0437 0.9894 1985517 ChemDiv2_003799 Cc1cc(C)nc(SC/C(=N\O)/N)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M16 compound treatment 1172661.0 411000.0 0.87 1030036.0 405000.0 0.92 1.2669 0.9996 1606282 ChemDiv2_003800 Cc1sc2nc(SCC(=O)N3CCCC3)[nH]c(=O)c2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M17 compound treatment 1157087.0 395000.0 0.84 987349.0 363000.0 0.82 1.1749 1.0 1426057 ChemDiv2_003801 O=c1[nH]cc(n2c(=O)c3ccccc3c4ccccc4c2=O)c(=O)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M18 compound treatment 1206095.0 444000.0 0.94 1043533.0 419000.0 0.95 1.3387 1.0 1428395 ChemDiv2_003802 COC(=O)c1sc2ccccc2c1NC(=O)c3ccc(cc3)N4C(=O)CCC4=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M19 compound treatment 1334423.0 572000.0 1.21 947212.0 322000.0 0.73 1.3762 0.9709 1256333 ChemDiv2_003803 COc1cc(C)nc(n1)N(C)S(=O)(=O)c2ccccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M20 compound treatment 1214025.0 452000.0 0.96 880398.0 256000.0 0.58 1.0883 0.9713 1461325 ChemDiv2_003804 CCN(CC)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M21 compound treatment 1182951.0 421000.0 0.89 923483.0 299000.0 0.68 1.111 0.9909 1985518 ChemDiv2_003805 ClC1=CCC2C(C1)C(=O)N(CC(=O)Nc3sc4CCCc4c3C#N)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M22 compound treatment 1008642.0 246000.0 0.52 845457.0 221000.0 0.5 0.7243 0.9998 1985519 ChemDiv2_003806 CC(C)Nc1nc(NC(C)C)nc(n1)N(C)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M23 mock treatment 828602.0 66400.0 0.14 831128.0 206000.0 0.47 0.4314 0.8806 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 M24 mock treatment 549419.0 -213000.0 -0.45 552336.0 -72400.0 -0.16 -0.4353 -0.9068 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N01 compound treatment 486436.0 -276000.0 -0.58 567548.0 -57200.0 -0.13 -0.5053 -0.8438 1985520 ChemDiv2_003807 Oc1nc2cc(Cl)ccc2c(c1Sc3nnc[nH]3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N02 compound treatment 1051691.0 290000.0 0.61 1068600.0 444000.0 1.01 1.1475 0.9716 1137093 ChemDiv2_003808 Oc1ccccc1n2c(nc3ccccc3c2=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N03 compound treatment 1021288.0 259000.0 0.55 1272614.0 648000.0 1.47 1.4299 0.9096 1590333 ChemDiv2_003809 Cc1nn(c2ccccc2C(=O)O)c(=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N04 compound treatment 1150771.0 389000.0 0.82 1130068.0 505000.0 1.15 1.3949 0.9867 1528365 ChemDiv2_003810 CCC(CC)c1nc2cc(OC)c(OC)cc2c(=O)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N05 compound treatment 1087195.0 325000.0 0.69 1188272.0 563000.0 1.28 1.3932 0.9577 1389197 ChemDiv2_003811 NC(=O)CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N06 compound treatment 1027972.0 266000.0 0.56 1227687.0 603000.0 1.37 1.3677 0.9229 1985521 ChemDiv2_003812 Cc1ccc(NC(=O)CSc2nccn2C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N07 compound treatment 1150642.0 388000.0 0.82 1337967.0 713000.0 1.62 1.7289 0.9507 1242910 ChemDiv2_003813 Cc1nc2ccccc2c(O)c1CN3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N08 compound treatment 1094668.0 333000.0 0.7 1376036.0 751000.0 1.71 1.7062 0.9234 1205134 ChemDiv2_003814 COc1ccc(cc1)c2nc(SCC=C)n(CC=C)c(=O)c2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N09 compound treatment 1233902.0 472000.0 1.0 1432586.0 808000.0 1.84 2.0058 0.9592 1448790 ChemDiv2_003815 CSc1nc2sc-3c(CCc4ccccc34)c2c(=O)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N10 compound treatment 1217898.0 456000.0 0.97 1323854.0 699000.0 1.59 1.807 0.9715 1246434 ChemDiv2_003816 CCOC(=O)C(CC)Oc1ccc2c(=O)c(coc2c1)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N11 compound treatment 1115053.0 353000.0 0.75 1417024.0 792000.0 1.8 1.8027 0.9242 1935835 ChemDiv2_003817 CCn1c2C(=O)CCCc2c3cc(C)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N12 compound treatment 1127467.0 365000.0 0.77 1492931.0 868000.0 1.97 1.9433 0.9165 1166230 ChemDiv2_003818 O=C(CSc1nnc[nH]1)N2c3ccccc3CCc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N13 compound treatment 1188313.0 426000.0 0.9 1456543.0 832000.0 1.89 1.976 0.9428 1002464 ChemDiv2_003819 CC(C)Nc1ncnc2n(ncc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N14 compound treatment 1097794.0 336000.0 0.71 1525806.0 901000.0 2.05 1.9517 0.9 1309191 ChemDiv2_003820 Nc1nc2CCCCCc2c(c1C#N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N15 compound treatment 921634.0 159000.0 0.34 1484887.0 860000.0 1.96 1.6218 0.8172 1985522 ChemDiv2_003821 Cn1c(Cn2ccnc2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N16 compound treatment 1057572.0 295000.0 0.63 1621146.0 996000.0 2.27 2.0447 0.87 1713545 ChemDiv2_003822 CC(=O)Oc1ccc(cc1)N2C(=O)C3ON(C(C3C2=O)c4ccc(F)cc4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N17 compound treatment 1141188.0 379000.0 0.8 1553511.0 929000.0 2.11 2.0613 0.9124 1447756 ChemDiv2_003823 CCN(CC)C(=O)c1ccc2nc(NC(=O)c3ccc(OC(=O)C)cc3)sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N18 compound treatment 1024972.0 263000.0 0.56 1631863.0 1010000.0 2.29 2.013 0.8542 1985523 ChemDiv2_003824 Clc1ccc(cc1)n2nc(C(=O)Nc3cccc(Cl)c3)c4ccccc4c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N19 compound treatment 1259868.0 498000.0 1.06 1497503.0 873000.0 1.98 2.1491 0.9563 1699139 ChemDiv2_003825 COC(=O)c1c(C)oc2cc(Br)c(OC)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N20 compound treatment 1169249.0 407000.0 0.86 1405632.0 781000.0 1.78 1.8656 0.9451 1602961 ChemDiv2_003826 C=CCN(CC=C)Cc1c[nH]c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N21 compound treatment 1164057.0 402000.0 0.85 1392005.0 767000.0 1.74 1.8359 0.9457 1430085 ChemDiv2_003827 Cc1cc2nn(nc2cc1NC(=O)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N22 compound treatment 1046751.0 285000.0 0.6 1366680.0 742000.0 1.69 1.6193 0.9039 1124306 ChemDiv2_003828 O=c1n(CC2CCCO2)c(=O)c3ccccc3c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N23 mock treatment 1019172.0 257000.0 0.54 1036669.0 412000.0 0.94 1.0475 0.9668 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 N24 mock treatment 536307.0 -226000.0 -0.48 506770.0 -118000.0 -0.27 -0.5283 -0.9625 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O01 compound treatment 389689.0 -372000.0 -0.79 524093.0 -101000.0 -0.23 -0.7202 -0.876 1249595 ChemDiv2_003829 COC(=O)c1ccc(cc1)N2C(=O)C3ON(C(C3C2=O)c4ccc(OC)cc4OC)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O02 compound treatment 1008772.0 247000.0 0.52 1137957.0 513000.0 1.17 1.1947 0.9344 1579499 ChemDiv2_003830 Cc1cccnc1n2c(CCN3C(=O)c4ccccc4C3=O)nc5ccccc5c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O03 compound treatment 971832.0 210000.0 0.44 1289005.0 664000.0 1.51 1.3822 0.878 1985524 ChemDiv2_003831 Brc1ccc(cc1)N2C(SCC2=O)c3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O04 compound treatment 1093071.0 331000.0 0.7 1231361.0 607000.0 1.38 1.4712 0.9509 1214662 ChemDiv2_003832 CC(=O)NS(=O)(=O)c1ccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O05 compound treatment 952245.0 190000.0 0.4 1259498.0 635000.0 1.44 1.3054 0.8712 1411065 ChemDiv2_003833 CC(=O)Nc1nc(CC(=O)O)cs1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O06 compound treatment 1411717.0 650000.0 1.38 1320364.0 696000.0 1.58 2.092 0.9976 1686502 ChemDiv2_003834 CC(c1nnc(NC(=O)c2ccc3OCOc3c2)s1)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O07 compound treatment 973587.0 211000.0 0.45 1360287.0 736000.0 1.67 1.4994 0.8661 1295273 ChemDiv2_003835 CC(C)Cn1c(nc2n(C)c(=O)[nH]c(=O)c12)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O08 compound treatment 1261780.0 500000.0 1.06 1368665.0 744000.0 1.69 1.9449 0.9746 1109371 ChemDiv2_003836 Cn1c(NCCc2ccccc2)nc3n(C)c(=O)n(C)c(=O)c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O09 compound treatment 1301148.0 539000.0 1.14 1400638.0 776000.0 1.76 2.0553 0.9779 1985525 ChemDiv2_003837 Clc1ccccc1c2nc(no2)C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O10 compound treatment 1183641.0 421000.0 0.89 1236289.0 612000.0 1.39 1.6149 0.9772 1576029 ChemDiv2_003838 CCn1c(=N)n(CC(O)c2cccs2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O11 compound treatment 1490629.0 728000.0 1.54 1327345.0 703000.0 1.6 2.2215 0.9999 1211212 ChemDiv2_003839 CCn1c2ccccc2c3nnc(SCN4C(=O)c5ccccc5C4=O)nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O12 compound treatment 1434406.0 672000.0 1.43 1326769.0 702000.0 1.6 2.1363 0.9984 1210332 ChemDiv2_003840 CC(C)(C)C(=O)Cn1c(=N)n(CC=C)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O13 compound treatment 1467709.0 706000.0 1.5 1276820.0 652000.0 1.48 2.1059 1.0 1721613 ChemDiv2_003841 CC1(C)Cc2c(sc3ncn4nc(nc4c23)c5ccncc5)C(C)(C)N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O14 compound treatment 1365242.0 603000.0 1.28 1490493.0 866000.0 1.97 2.2958 0.9782 1248335 ChemDiv2_003842 CC(=O)OCCn1c(=O)c2cc3c(=O)n(CCOC(=O)C)c(=O)c3cc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O15 compound treatment 1334438.0 572000.0 1.21 1452529.0 828000.0 1.88 2.1886 0.9774 1398101 ChemDiv2_003843 COc1ccc(CN2CCN(CC2)C(=O)CC(C)C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O16 compound treatment 1306515.0 544000.0 1.15 1545846.0 921000.0 2.09 2.2968 0.9606 1669303 ChemDiv2_003844 CC(C)CSc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O17 compound treatment 1271759.0 510000.0 1.08 1360138.0 735000.0 1.67 1.9461 0.9777 1528874 ChemDiv2_003845 Cc1cc(C)nc(Nc2ncc(O)n2c3ccc(C)c(C)c3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O18 compound treatment 1167766.0 406000.0 0.86 1405637.0 781000.0 1.78 1.8634 0.9446 1401181 ChemDiv2_003846 O=C(Nc1cccc(c1)c2nc3ccccc3[nH]2)c4cccc(c4)N5C(=O)CCC5=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O19 compound treatment 1588432.0 826000.0 1.75 1155503.0 531000.0 1.21 2.0918 0.9834 1985526 ChemDiv2_003847 CN(C)c1nc(OCCOC(=O)C)nc(n1)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O20 compound treatment 1433410.0 671000.0 1.42 1200198.0 575000.0 1.31 1.9313 0.9991 1169554 ChemDiv2_003848 CC1(C)CC(=O)C2=C(C1)Nc3[nH]c(=O)[nH]c(=O)c3C2c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O21 compound treatment 1253506.0 491000.0 1.04 1000692.0 376000.0 0.85 1.3409 0.9952 1654469 ChemDiv2_003849 CCCC(=O)Nc1nnc(s1)c2cccc(OCC)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O22 compound treatment 1077157.0 315000.0 0.67 1010409.0 386000.0 0.88 1.0922 0.991 1464046 ChemDiv2_003850 CC(C)(C)C(=O)Nc1ncnc2sc3CCCCc3c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O23 mock treatment 783244.0 21100.0 0.04 829210.0 204000.0 0.46 0.3603 0.7716 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 O24 mock treatment 399328.0 -363000.0 -0.77 444277.0 -180000.0 -0.41 -0.8341 -0.9567 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P01 compound treatment 334488.0 -428000.0 -0.91 425796.0 -199000.0 -0.45 -0.961 -0.9484 1601526 ChemDiv2_003851 Cc1cc(NC(=O)CSc2ccccn2)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P02 compound treatment 386696.0 -375000.0 -0.8 514509.0 -110000.0 -0.25 -0.7401 -0.8869 1985527 ChemDiv2_003852 CCOC(=O)c1cnc2ccccc2c1NCCCN3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P03 compound treatment 496338.0 -266000.0 -0.56 599581.0 -25200.0 -0.06 -0.439 -0.775 1170375 ChemDiv2_003853 Brc1ccc2[nH]c(=O)c(NC(=O)CNS(=O)(=O)c3ccccc3)c(c4ccccc4)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P04 compound treatment 824596.0 62400.0 0.13 722276.0 97500.0 0.22 0.2504 0.9696 1429901 ChemDiv2_003854 Cc1cccc(NC(=O)CSc2nsc(SCC(=O)Nc3cccc(C)c3)n2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P05 compound treatment 997038.0 235000.0 0.5 811371.0 187000.0 0.42 0.6521 0.9968 1109378 ChemDiv2_003855 c1ccc(cc1)c2noc(n2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P06 compound treatment 915917.0 154000.0 0.33 894298.0 270000.0 0.61 0.6638 0.9564 1852059 ChemDiv2_003856 CC1=C(C(C2=C(CCCC2=O)N1)c3cccc(Cl)c3Cl)C(=O)Nc4ccccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P07 compound treatment 1070231.0 308000.0 0.65 969925.0 345000.0 0.78 1.0167 0.9958 1404602 ChemDiv2_003857 CCN1CCN(Cc2c(C)nc3ccc(C)cc3c2O)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P08 compound treatment 1054862.0 293000.0 0.62 1062026.0 437000.0 0.99 1.1417 0.9743 1550131 ChemDiv2_003858 OC(CN1C(=O)c2ccccc2S1(=O)=O)CN3c4ccccc4Sc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P09 compound treatment 1161848.0 400000.0 0.85 1007414.0 383000.0 0.87 1.2143 0.9999 1433402 ChemDiv2_003859 COC(=O)c1[nH]c2CCCC(=O)c2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P10 compound treatment 1140579.0 378000.0 0.8 1074925.0 450000.0 1.02 1.291 0.9927 1350186 ChemDiv2_003860 CC(C)OC(=O)COc1ccc2c(=O)c(coc2c1)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P11 compound treatment 1145198.0 383000.0 0.81 1049415.0 425000.0 0.97 1.2569 0.9963 1223281 ChemDiv2_003861 CCn1c2C(=O)CCCc2c3cc(ccc13)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P12 compound treatment 225981.0 -536000.0 -1.14 281477.0 -343000.0 -0.78 -1.3556 -0.9832 1590353 ChemDiv2_003862 Cc1nccn1CC(=O)N2c3ccccc3Sc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P13 compound treatment 1135584.0 373000.0 0.79 939070.0 314000.0 0.71 1.0651 0.9987 1528981 ChemDiv2_003863 COc1ccc(Nc2ncnc3n(ncc23)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P14 compound treatment 1162947.0 401000.0 0.85 1234194.0 609000.0 1.39 1.5805 0.9724 1494576 ChemDiv2_003864 CC(C)c1ccc(cc1)c2c3CCCc3nc(N)c2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P15 compound treatment 1143215.0 381000.0 0.81 1317131.0 692000.0 1.57 1.6843 0.952 1619071 ChemDiv2_003865 COc1ccc(Nc2nnc(c3ccc(cc3)C(=O)NCCO)c4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P16 compound treatment 1133206.0 371000.0 0.79 1150600.0 526000.0 1.2 1.4016 0.9794 1599355 ChemDiv2_003866 O=C(Cn1cnc2ccccc2c1=O)Nc3ccc(Oc4ccccc4)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P17 compound treatment 1101735.0 340000.0 0.72 1131392.0 507000.0 1.15 1.3235 0.9744 1678180 ChemDiv2_003867 CC1CCCN(Cc2c(O)ccc3cc(c4nc5ccccc5[nH]4)c(=O)oc23)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P18 compound treatment 1176636.0 414000.0 0.88 1159268.0 534000.0 1.22 1.4806 0.9873 1985528 ChemDiv2_003868 CCn1c(C(=O)O)c(CC(=O)Nc2ccccc2OC)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P19 compound treatment 710244.0 -51900.0 -0.11 785978.0 161000.0 0.37 0.1813 0.4739 1693929 ChemDiv2_003869 CCN(CC)CC(O)Cn1c(C)c(C)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P20 compound treatment 830613.0 68500.0 0.15 648315.0 23500.0 0.05 0.1405 0.9081 1485807 ChemDiv2_003870 CN(C)C(=O)c1cc(nc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P21 compound treatment 683023.0 -79100.0 -0.17 610744.0 -14000.0 -0.03 -0.1412 -0.8267 1734260 ChemDiv2_003871 Fc1ccc(cc1)c2ccc(o2)C(=O)Nc3ccc4oc(nc4c3)c5cccnc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P22 compound treatment 641754.0 -120000.0 -0.26 509510.0 -115000.0 -0.26 -0.3658 -0.9999 1398066 ChemDiv2_003872 CSc1nnc(SCc2nc3ccccc3[nH]2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P23 mock treatment 493582.0 -269000.0 -0.57 478670.0 -146000.0 -0.33 -0.6375 -0.9671 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1379 P24 mock treatment 443353.0 -319000.0 -0.68 359246.0 -266000.0 -0.6 -0.9048 -0.9984 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A01 compound treatment 418714.0 -312000.0 -0.66 389389.0 -355000.0 -0.81 -1.0387 -0.995 1985529 ChemDiv2_003873 OCCN1C(=O)C2CC=C(Cl)CC2C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A02 compound treatment 430717.0 -300000.0 -0.64 461367.0 -283000.0 -0.64 -0.905 -1.0 1985530 ChemDiv2_003874 COC(=O)CNc1nc(Cl)nc(Nc2ccc(I)cc2C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A03 compound treatment 464481.0 -266000.0 -0.56 615461.0 -129000.0 -0.29 -0.6067 -0.9538 1787243 ChemDiv2_003875 CCn1c(NCc2nc3ccccc3n2C)nc4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A04 compound treatment 444364.0 -286000.0 -0.61 657508.0 -87200.0 -0.2 -0.5692 -0.8918 1278506 ChemDiv2_003876 CSc1nc2ccccc2c(=O)n1C3CCOC(C)(C)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A05 compound treatment 678693.0 -51900.0 -0.11 681335.0 -63400.0 -0.14 -0.1796 -0.9911 1585132 ChemDiv2_003877 COC(=O)c1ccc(CSc2nc3ccccc3c(=O)n2CC=C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A06 compound treatment 405171.0 -325000.0 -0.69 489663.0 -255000.0 -0.58 -0.8978 -0.9963 1348462 ChemDiv2_003878 CNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3cccc(C)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A07 compound treatment 472971.0 -258000.0 -0.55 719036.0 -25700.0 -0.06 -0.4274 -0.7783 1676456 ChemDiv2_003879 CCOc1ccc(cc1)c2cc(=O)c3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A08 compound treatment 520271.0 -210000.0 -0.45 507155.0 -238000.0 -0.54 -0.6971 -0.9955 1147108 ChemDiv2_003880 CN(C)CCOc1nc(nc2c3ccccc3oc12)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A09 compound treatment 425527.0 -305000.0 -0.65 761475.0 16800.0 0.04 -0.4303 -0.6643 1852741 ChemDiv2_003881 CC1=C(C(C2=C(CC(CC2=O)c3ccccc3)N1)c4ccccc4)C(=O)Nc5ccccc5F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A10 compound treatment 481724.0 -249000.0 -0.53 767703.0 23000.0 0.05 -0.3361 -0.6339 1788959 ChemDiv2_003882 CCCCn1c(SCC(=O)N)nc2n(C)c(=O)n(C)c(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A11 compound treatment 465608.0 -265000.0 -0.56 872776.0 128000.0 0.29 -0.1913 -0.3024 1940697 ChemDiv2_003883 CSc1nnc2sc3ccccc3n12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A12 compound treatment 462671.0 -268000.0 -0.57 630660.0 -114000.0 -0.26 -0.5849 -0.9369 1189819 ChemDiv2_003884 CN1C(=O)C(Cc2nc3ccccc3c(=O)n2c4ccccc4)c5cc(Br)ccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A13 compound treatment 468890.0 -262000.0 -0.55 439178.0 -306000.0 -0.69 -0.8834 -0.9938 1985531 ChemDiv2_003885 CCC(C)C1C(=C(N)OC2=C1C(=O)CC(C)(C)C2)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A14 compound treatment 811375.0 80800.0 0.17 720531.0 -24200.0 -0.05 0.0823 0.4572 1677801 ChemDiv2_003886 CN(Cc1ccccc1)c2ncnc3ccc(Br)cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A15 compound treatment 968709.0 238000.0 0.5 893067.0 148000.0 0.34 0.5955 0.9808 1183872 ChemDiv2_003887 Cc1nnc(NC(=O)C2c3ccccc3Oc4ccccc24)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A16 compound treatment 867802.0 137000.0 0.29 890255.0 146000.0 0.33 0.4397 0.9979 1467768 ChemDiv2_003888 Cc1ccc2nc(SCc3nc4ccccc4n3C)[nH]c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A17 compound treatment 568524.0 -162000.0 -0.34 602415.0 -142000.0 -0.32 -0.4717 -0.9996 1596259 ChemDiv2_003889 COc1ccc(OCC(=O)OCCN2C(=O)c3ccccc3C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A18 compound treatment 897514.0 167000.0 0.35 879026.0 134000.0 0.31 0.4662 0.9973 1585824 ChemDiv2_003890 COc1ccc(C2N(CCCN(C)C)C(=O)C(=C2C(=O)c3cccs3)O)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A19 compound treatment 755894.0 25300.0 0.05 760278.0 15600.0 0.04 0.063 0.9795 1180824 ChemDiv2_003891 CC(C)CNc1ncnc2c3cc4COC(C)(C)Cc4nc3sc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A20 compound treatment 941478.0 211000.0 0.45 842066.0 97400.0 0.22 0.4727 0.9474 1421738 ChemDiv2_003892 COc1ccc2oc(c(C(=O)O)c2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A21 compound treatment 1089221.0 359000.0 0.76 938262.0 194000.0 0.44 0.8488 0.9662 1388493 ChemDiv2_003893 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3nccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A22 compound treatment 960390.0 230000.0 0.49 800894.0 56200.0 0.13 0.4348 0.8633 1134604 ChemDiv2_003894 CCOc1ccc2nc(C)c(CN(CC=C)CC=C)c(O)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A23 mock treatment 549319.0 -181000.0 -0.38 645900.0 -98800.0 -0.22 -0.4305 -0.9673 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 A24 mock treatment 484396.0 -246000.0 -0.52 435798.0 -309000.0 -0.7 -0.8656 -0.9893 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B01 compound treatment 494762.0 -236000.0 -0.5 510524.0 -234000.0 -0.53 -0.73 -0.9995 1985532 ChemDiv2_003895 CCS(=O)(=O)CCSc1nc2ccccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B02 compound treatment 911802.0 181000.0 0.38 1043226.0 299000.0 0.68 0.7516 0.9637 1985533 ChemDiv2_003896 Cc1csc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B03 compound treatment 923606.0 193000.0 0.41 911040.0 166000.0 0.38 0.5568 0.9992 1407872 ChemDiv2_003897 COc1ccc(cc1)C(=O)c2c(C)c3ccccc3n2CC(O)CNC(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B04 compound treatment 1077522.0 347000.0 0.74 1169911.0 425000.0 0.97 1.2037 0.9909 1412975 ChemDiv2_003898 O=C(Cc1ccccc1)NCC2OCCc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B05 compound treatment 1185257.0 455000.0 0.96 1021520.0 277000.0 0.63 1.1266 0.9787 1462746 ChemDiv2_003899 Cc1cccc(n1)N2C(=O)c3cccc4cccc(C2=O)c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B06 compound treatment 1269855.0 539000.0 1.14 986750.0 242000.0 0.55 1.1975 0.9438 1364030 ChemDiv2_003900 CCOC(=O)N1CCN(CC1)C(=O)c2ccc(Br)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B07 compound treatment 1064392.0 334000.0 0.71 1295317.0 551000.0 1.25 1.3856 0.9635 1507536 ChemDiv2_003901 Cc1cccc(c1)C2C3C(=O)c4ccccc4C3=Nc5c2c(=O)n(C)c(=O)n5C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B08 compound treatment 1047248.0 317000.0 0.67 1134469.0 390000.0 0.89 1.1013 0.9906 1378763 ChemDiv2_003902 Cc1nc2ccccc2c3nc(NC(=O)c4ccc5nsnc5c4)nn13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B09 compound treatment 962587.0 232000.0 0.49 1212434.0 468000.0 1.06 1.0997 0.9386 1681748 ChemDiv2_003903 Cc1nnc(NC2CCCCC2)n(C)c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B10 compound treatment 1184305.0 454000.0 0.96 1121409.0 377000.0 0.86 1.2858 0.9983 1246768 ChemDiv2_003904 Cc1ccc(cc1)N2CC(CC2=O)C(=O)N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B11 compound treatment 1087854.0 357000.0 0.76 1289417.0 545000.0 1.24 1.4113 0.9722 1145131 ChemDiv2_003905 Oc1ccccc1c2nc(N3CCCCC3)c4ccccc4n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B12 compound treatment 1198103.0 468000.0 0.99 1224921.0 480000.0 1.09 1.4729 0.9988 1985534 ChemDiv2_003906 CC(C)c1nnc2c3c4CCCCc4sc3ncn12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B13 compound treatment 1151773.0 421000.0 0.89 1097767.0 353000.0 0.8 1.199 0.9986 1618238 ChemDiv2_003907 CC(C)(C)c1ccc(cc1)c2nc(no2)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B14 compound treatment 1042408.0 312000.0 0.66 1182028.0 437000.0 0.99 1.1705 0.9803 1461551 ChemDiv2_003908 CC(C)COC(=O)COc1ccc2c(=O)c(coc2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B15 compound treatment 964725.0 234000.0 0.5 1085302.0 341000.0 0.77 0.8986 0.9769 1433715 ChemDiv2_003909 CCOC(=O)c1c(C)oc2c1c(C(N3CCOCC3)c4cccnc4)c(O)c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B16 compound treatment 1024832.0 294000.0 0.62 1104526.0 360000.0 0.82 1.0196 0.9911 1744845 ChemDiv2_003910 C(Sc1nnc(c2ccco2)c(n1)c3ccco3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B17 compound treatment 1037011.0 306000.0 0.65 1081867.0 337000.0 0.77 1.0014 0.9966 1519762 ChemDiv2_003911 CC1CCCCN1Cc2c(O)ccc3cc(c4nc5ccccc5n4C)c(=O)oc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B18 compound treatment 1251042.0 520000.0 1.1 1114030.0 369000.0 0.84 1.3739 0.9909 1702985 ChemDiv2_003912 CCCN(CCC)c1nc(Cl)nc(NCCN2CCOCC2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B19 compound treatment 1313232.0 583000.0 1.24 966894.0 222000.0 0.51 1.2306 0.9221 1788904 ChemDiv2_003913 CCOc1cc(ccc1O)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B20 compound treatment 1196429.0 466000.0 0.99 1020206.0 275000.0 0.63 1.1412 0.9759 1985535 ChemDiv2_003914 O=C(CN1C(=O)C2C3CC(C=C3)C2C1=O)Nc4nc(cs4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B21 compound treatment 1048383.0 318000.0 0.67 996936.0 252000.0 0.57 0.8819 0.9968 1985536 ChemDiv2_003915 CCc1c(C)c2c(C)n[nH]c2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B22 compound treatment 1137201.0 407000.0 0.86 952919.0 208000.0 0.47 0.9443 0.9602 988 ChemDiv2_003916 COc1ccc2[nH]cc(CCNC(=O)C)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B23 mock treatment 1051222.0 321000.0 0.68 1081858.0 337000.0 0.77 1.0227 0.9982 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 B24 mock treatment 489819.0 -241000.0 -0.51 576034.0 -169000.0 -0.38 -0.6321 -0.9901 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C01 compound treatment 595417.0 -135000.0 -0.29 532388.0 -212000.0 -0.48 -0.5439 -0.969 1447858 ChemDiv2_003917 OC1(Cc2ccccc2)N(C(=O)c3ccccc31)c4ccc5OCOc5c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C02 compound treatment 817790.0 87200.0 0.18 843036.0 98300.0 0.22 0.2888 0.9956 1985537 ChemDiv2_003918 Cn1c(Sc2nc3ccccc3n2CC(=O)NC4CCCCC4)nc5n(C)c(=O)n(C)c(=O)c15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C03 compound treatment 939104.0 209000.0 0.44 845676.0 101000.0 0.23 0.4749 0.9534 1211055 ChemDiv2_003919 COC(=O)Oc1ccc2c(=O)c(coc2c1)c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C04 compound treatment 885554.0 155000.0 0.33 938208.0 193000.0 0.44 0.5434 0.9897 1710707 ChemDiv2_003920 CCn1c(SCC(=O)N)nc2-c3ccccc3CC4(CCCCC4)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C05 compound treatment 891057.0 160000.0 0.34 914028.0 169000.0 0.38 0.5128 0.9981 1985538 ChemDiv2_003921 Cc1nnc(SCC(=O)O)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C06 compound treatment 980292.0 250000.0 0.53 1067749.0 323000.0 0.73 0.8937 0.9871 1700221 ChemDiv2_003922 Cn1c(=O)[nH]c(=O)c2n(CCCc3ccccc3)c(nc12)N4CCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C07 compound treatment 979618.0 249000.0 0.53 956370.0 212000.0 0.48 0.7136 0.9989 1018152 ChemDiv2_003923 Oc1ccc(cc1)c2cc(=O)c3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C08 compound treatment 1152347.0 422000.0 0.89 1041382.0 297000.0 0.67 1.1092 0.9903 1985539 ChemDiv2_003924 O=c1n(c(CSc2ncnc3ccccc23)nc4ccccc14)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C09 compound treatment 1001405.0 271000.0 0.57 957634.0 213000.0 0.48 0.7483 0.9964 1389664 ChemDiv2_003925 Cc1cc(C)n(n1)C(=O)C2COc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C10 compound treatment 982340.0 252000.0 0.53 1063963.0 319000.0 0.73 0.8907 0.9886 1607669 ChemDiv2_003926 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)C3CN(C(=O)C3)c4ccccc4)cc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C11 compound treatment 1087658.0 357000.0 0.76 975707.0 231000.0 0.53 0.9067 0.984 1370661 ChemDiv2_003927 OCCNc1ncnc2oc(c(c3ccccc3)c12)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C12 compound treatment 1242529.0 512000.0 1.09 1217568.0 473000.0 1.08 1.5276 1.0 1931121 ChemDiv2_003928 CCOc1ccc(CSc2nnc[nH]2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C13 compound treatment 1125971.0 395000.0 0.84 1006891.0 262000.0 0.6 1.0142 0.986 1741267 ChemDiv2_003929 CCSC1=C(C#N)C2(CCN(C)CC2)C(C#N)C(=O)N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C14 compound treatment 1132334.0 402000.0 0.85 1073252.0 329000.0 0.75 1.1304 0.9979 1194253 ChemDiv2_003930 CCN1CCN(CC1)c2ncnc3ccc(Br)cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C15 compound treatment 1082349.0 352000.0 0.75 1053789.0 309000.0 0.7 1.0242 0.9996 1681515 ChemDiv2_003931 Cc1cc(NC(=O)CCc2ccccc2)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C16 compound treatment 967154.0 237000.0 0.5 1062601.0 318000.0 0.72 0.8657 0.9841 1101145 ChemDiv2_003932 CCOC(=O)CSc1nnc(o1)c2cc(OC)c(OC)c(OC)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C17 compound treatment 982454.0 252000.0 0.53 1012599.0 268000.0 0.61 0.8083 0.9979 1335202 ChemDiv2_003933 CC(C)c1ccc(C)cc1OCC(=O)OCCN2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C18 compound treatment 1227297.0 497000.0 1.05 1017638.0 273000.0 0.62 1.1834 0.9682 1218864 ChemDiv2_003934 Cc1nnc(s1)N2C(C(=C(O)C2=O)C(=O)c3cccs3)c4ccccc4F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C19 compound treatment 1079592.0 349000.0 0.74 906346.0 162000.0 0.37 0.7831 0.9478 1478851 ChemDiv2_003935 O=C(c1cccc(c1)C(=O)n2cnc3ccccc23)n4cnc5ccccc45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C20 compound treatment 1001187.0 271000.0 0.57 850647.0 106000.0 0.24 0.576 0.9257 1624361 ChemDiv2_003936 CCc1oc2cc(O)ccc2c(=O)c1c3nc4ccccc4n3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C21 compound treatment 943276.0 213000.0 0.45 1021643.0 277000.0 0.63 0.7641 0.9866 1374492 ChemDiv2_003937 Cc1cccc2c(C)nc(Nc3nc(=O)c4ccccc4n3C)nc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C22 compound treatment 943450.0 213000.0 0.45 913679.0 169000.0 0.38 0.5908 0.9968 1936152 ChemDiv2_003938 CCOC(=O)/C(=N/O)/C1=NC(C)(C)Cc2cc(OC)c(OC)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C23 mock treatment 915654.0 185000.0 0.39 783629.0 38900.0 0.09 0.34 0.8453 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 C24 mock treatment 696735.0 -33800.0 -0.07 539266.0 -205000.0 -0.47 -0.381 -0.8062 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D01 compound treatment 509944.0 -221000.0 -0.47 487681.0 -257000.0 -0.58 -0.7439 -0.9939 1985540 ChemDiv2_003939 CC(C)Nc1nc(NC(C)C)nc(OCCOC(=O)Nc2ccccc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D02 compound treatment 665940.0 -64600.0 -0.14 810811.0 66100.0 0.15 0.0094 0.0462 1985541 ChemDiv2_003940 COC(=O)C(CC(C)C)NC(=O)C1c2ccccc2Oc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D03 compound treatment 934064.0 204000.0 0.43 778290.0 33600.0 0.08 0.359 0.8195 1556856 ChemDiv2_003941 CC1(CC2C(C(=O)N3CCOCC3)C(=O)N1CC=C)Oc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D04 compound treatment 694118.0 -36400.0 -0.08 891812.0 147000.0 0.33 0.1818 0.5298 1163961 ChemDiv2_003942 Cc1cc(=O)[nH]c2[nH]nc(c3ccccc3)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D05 compound treatment 916921.0 186000.0 0.4 985297.0 241000.0 0.55 0.6661 0.9872 1460437 ChemDiv2_003943 COc1ccc(cc1)N2C(SCC2=O)c3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D06 compound treatment 913603.0 183000.0 0.39 920958.0 176000.0 0.4 0.5577 0.9999 1199261 ChemDiv2_003944 CCOC(=O)c1c(C)n(c2ccc(OC)cc2)c3ccc(OCC(=O)N)cc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D07 compound treatment 923236.0 193000.0 0.41 876464.0 132000.0 0.3 0.5006 0.9884 1471249 ChemDiv2_003945 COc1ccc(OC)c(c1)N2C(=O)CC(Sc3nc4ccccc4s3)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D08 compound treatment 1018436.0 288000.0 0.61 1025572.0 281000.0 0.64 0.8831 0.9997 1985542 ChemDiv2_003946 O=C(CN1C(=O)C2C3CC(C=C3)C2C1=O)Nc4nncs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D09 compound treatment 1002401.0 272000.0 0.58 1101553.0 357000.0 0.81 0.9812 0.986 1359643 ChemDiv2_003947 COc1ccc(CCNc2nnc(c3ccccc3)c(=O)n2C)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D10 compound treatment 1088439.0 358000.0 0.76 674381.0 -70300.0 -0.16 0.4234 0.5461 1985543 ChemDiv2_003948 CCOc1cc(cc(Br)c1OCC)C2C(=CNC=C2C(=O)OC)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D11 compound treatment 911447.0 181000.0 0.38 997986.0 253000.0 0.58 0.6783 0.9805 1625431 ChemDiv2_003949 CCOc1nc(nc2ccccc12)c3ccccc3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D12 compound treatment 1271235.0 541000.0 1.15 1362875.0 618000.0 1.41 1.8043 0.9949 1276008 ChemDiv2_003950 O=c1oc(nc2sc3CCCCc3c12)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D13 compound treatment 1039260.0 309000.0 0.65 1310002.0 565000.0 1.29 1.3715 0.951 1924112 ChemDiv2_003951 Cc1ccc(cc1)c2noc(CCc3ccccc3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D14 compound treatment 1016579.0 286000.0 0.61 1156446.0 412000.0 0.94 1.0907 0.9779 1331248 ChemDiv2_003952 CN(Cc1c(O)ccc2c(=O)c(coc12)c3ccccc3)C4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D15 compound treatment 928651.0 198000.0 0.42 1155560.0 411000.0 0.93 0.9574 0.9349 1617188 ChemDiv2_003953 Cc1cc(=O)n([nH]1)c2nc3ccccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D16 compound treatment 957395.0 227000.0 0.48 1043182.0 298000.0 0.68 0.8199 0.9858 1985544 ChemDiv2_003954 CC1=CC(C)(C)N(C(=O)CSc2nccn2C)c3cc(C)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D17 compound treatment 1070255.0 340000.0 0.72 1011183.0 266000.0 0.61 0.9376 0.9963 1234210 ChemDiv2_003955 OCCN1CCN(Cc2c(O)ccc3cc(c4nc5ccccc5s4)c(=O)oc23)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D18 compound treatment 1102879.0 372000.0 0.79 1092532.0 348000.0 0.79 1.1173 1.0 1694731 ChemDiv2_003956 CCOc1nc(OCC)nc(n1)N2CCC(C)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D19 compound treatment 952045.0 221000.0 0.47 1051759.0 307000.0 0.7 0.8256 0.9814 1717287 ChemDiv2_003957 Cc1cccc(N(CC(=O)Nc2cccnc2)S(=O)(=O)C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D20 compound treatment 913965.0 183000.0 0.39 952480.0 208000.0 0.47 0.6089 0.9953 1985545 ChemDiv2_003958 CCOc1ccc2sc(NC(=O)CN3C(=O)C4C5CC(C=C5)C4C3=O)nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D21 compound treatment 966479.0 236000.0 0.5 902960.0 158000.0 0.36 0.6081 0.9869 1494460 ChemDiv2_003959 O=C(Nc1ccc(cc1)c2nc3ccccc3[nH]2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D22 compound treatment 854237.0 124000.0 0.26 762924.0 18200.0 0.04 0.2147 0.8087 1985546 ChemDiv2_003960 Nc1ccccc1c2nnc(SCC=C)nc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D23 mock treatment 874979.0 144000.0 0.31 746286.0 1570.0 0.0 0.219 0.7153 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 D24 mock treatment 632458.0 -98100.0 -0.21 561704.0 -183000.0 -0.42 -0.4413 -0.9486 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E01 compound treatment 630766.0 -99800.0 -0.21 537374.0 -207000.0 -0.47 -0.4829 -0.9346 1606935 ChemDiv2_003961 CC1CN(CC(C)O1)C(=O)c2cc(nc3ccccc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E02 compound treatment 597652.0 -133000.0 -0.28 854279.0 110000.0 0.25 -0.0231 -0.0614 1938346 ChemDiv2_003962 CCOC(=O)c1c(C)nc2sccn12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E03 compound treatment 747345.0 16800.0 0.04 956479.0 212000.0 0.48 0.3656 0.7573 1485500 ChemDiv2_003963 Oc1ccc2c(=O)c(coc2c1CN(CC=C)CC=C)c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E04 compound treatment 750618.0 20100.0 0.04 1071534.0 327000.0 0.74 0.5555 0.7463 1152641 ChemDiv2_003964 CC(=C)Cn1c(SCC(=O)N)nc2-c3ccccc3CC4(CCCC4)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E05 compound treatment 922148.0 192000.0 0.41 1077224.0 333000.0 0.76 0.8218 0.9576 1985547 ChemDiv2_003965 CCc1nnc(SCC(=O)OC)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E06 compound treatment 849236.0 119000.0 0.25 1069648.0 325000.0 0.74 0.7003 0.8973 1719946 ChemDiv2_003966 CN(Cc1ccccc1)c2nc3n(C)c(=O)[nH]c(=O)c3n2Cc4cccc(C)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E07 compound treatment 884109.0 154000.0 0.33 1079416.0 335000.0 0.76 0.7683 0.9282 1053054 ChemDiv2_003967 O=c1cc(oc2ccccc12)c3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E08 compound treatment 789494.0 58900.0 0.12 1060168.0 315000.0 0.72 0.5955 0.818 1553742 ChemDiv2_003968 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc3nccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E09 compound treatment 951714.0 221000.0 0.47 1065608.0 321000.0 0.73 0.8474 0.9771 1310466 ChemDiv2_003969 Brc1ccccc1C(=O)NCC2COc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E10 compound treatment 845576.0 115000.0 0.24 1150203.0 405000.0 0.92 0.8243 0.8644 1243246 ChemDiv2_003970 CC1(C)Cc2ccccc2C(=N1)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E11 compound treatment 1086502.0 356000.0 0.75 1108250.0 364000.0 0.83 1.118 0.999 1549340 ChemDiv2_003971 Cc1ccnc(c1)n2c(nc3ccccc3c2=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E12 compound treatment 881463.0 151000.0 0.32 1573014.0 828000.0 1.88 1.5578 0.8155 1355628 ChemDiv2_003972 CCOc1ccc(cc1)c2cc(C(=O)OC)c3ccccc3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E13 compound treatment 1217342.0 487000.0 1.03 1072056.0 327000.0 0.74 1.2559 0.9871 1737515 ChemDiv2_003973 COc1cccc(c1)C(=O)N2CCN(CC2)C(=O)c3cc(OC)cc(OC)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E14 compound treatment 1119392.0 389000.0 0.82 1137034.0 392000.0 0.89 1.2136 0.9992 1372546 ChemDiv2_003974 CCCCN(CC)c1ncnc2ccc(Br)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E15 compound treatment 868601.0 138000.0 0.29 1088360.0 344000.0 0.78 0.7594 0.9102 1321399 ChemDiv2_003975 CC(Oc1ccccc1)C(=O)Nc2cc(C)on2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E16 compound treatment 1086807.0 356000.0 0.76 1114640.0 370000.0 0.84 1.1287 0.9986 1985548 ChemDiv2_003976 Cc1cc(NCCO)nc(n1)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E17 compound treatment 1117858.0 387000.0 0.82 1137578.0 393000.0 0.89 1.2122 0.9991 1288449 ChemDiv2_003977 Brc1cccc(OCC(=O)OCCN2C(=O)c3ccccc3C2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E18 compound treatment 1123878.0 393000.0 0.83 1092917.0 348000.0 0.79 1.1494 0.9997 1670896 ChemDiv2_003978 COc1ccc(cc1)C(=O)C2=C(O)C(=O)N(CCN3CCNCC3)C2c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E19 compound treatment 1004908.0 274000.0 0.58 969088.0 224000.0 0.51 0.772 0.9979 1300061 ChemDiv2_003979 CN(C)c1ncnc2c3ccccc3[nH]c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E20 compound treatment 895128.0 165000.0 0.35 971795.0 227000.0 0.52 0.6118 0.9818 1147545 ChemDiv2_003980 COC(=O)c1c(C)oc2ccc(OCC(=O)N)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E21 compound treatment 884076.0 154000.0 0.33 1063526.0 319000.0 0.72 0.7427 0.9347 1370594 ChemDiv2_003981 CC(C)n1c(SCc2ccc(F)cc2)nc3n(C)c(=O)n(C)c(=O)c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E22 compound treatment 954630.0 224000.0 0.48 1011368.0 267000.0 0.61 0.7646 0.9927 1985549 ChemDiv2_003982 COc1cc2CC(C)(C)N=C(/C(=N\O)/C#N)c2cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E23 mock treatment 898219.0 168000.0 0.36 820118.0 75400.0 0.17 0.3725 0.9441 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 E24 mock treatment 517586.0 -213000.0 -0.45 586815.0 -158000.0 -0.36 -0.5731 -0.9935 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F01 compound treatment 942200.0 212000.0 0.45 882264.0 138000.0 0.31 0.5384 0.9844 1578373 ChemDiv2_003983 CN(C)c1nc(SCCO)nc(n1)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F02 compound treatment 1099322.0 369000.0 0.78 1099848.0 355000.0 0.81 1.1237 0.9999 1183244 ChemDiv2_003984 COCC(=O)Nc1nc2ccccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F03 compound treatment 1180940.0 450000.0 0.95 1185366.0 441000.0 1.0 1.3835 0.9997 1531823 ChemDiv2_003985 CN(C)C(=O)c1cc2cccc(CC=C)c2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F04 compound treatment 1133527.0 403000.0 0.85 1133717.0 389000.0 0.88 1.2294 0.9998 1690768 ChemDiv2_003986 Cc1nn(c2ccccc2)c3[nH]c(=O)cc(C)c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F05 compound treatment 1186116.0 456000.0 0.97 1135278.0 391000.0 0.89 1.3108 0.9991 1572670 ChemDiv2_003987 O=c1n(Cc2ccccc2)n(Cc3ccccc3)c(=O)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F06 compound treatment 1085340.0 355000.0 0.75 1182213.0 437000.0 0.99 1.2352 0.9905 1787081 ChemDiv2_003988 O=C1OC(NCc2cccnc2)(c3ccccc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F07 compound treatment 1049536.0 319000.0 0.68 1140685.0 396000.0 0.9 1.1147 0.9901 1985550 ChemDiv2_003989 CC1=CC(C)(C)N(C(=O)CSc2nc(C)cc(C)n2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F08 compound treatment 1083631.0 353000.0 0.75 1268462.0 524000.0 1.19 1.3713 0.975 1985551 ChemDiv2_003990 OCc1ccccc1NC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F09 compound treatment 1049296.0 319000.0 0.68 1414991.0 670000.0 1.52 1.5554 0.933 1985552 ChemDiv2_003991 CCOC(=O)c1sc2ncn(CC(=O)OCC(C)C)c(=O)c2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F10 compound treatment 1300547.0 570000.0 1.21 1409765.0 665000.0 1.51 1.9236 0.9938 1985553 ChemDiv2_003992 COC(=O)c1scc(C)c1NC(=O)C(C)Sc2nc(C)cc(C)c2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F11 compound treatment 1296747.0 566000.0 1.2 1697949.0 953000.0 2.17 2.3812 0.9612 1023746 ChemDiv2_003993 NCCc1c[nH]c2ccc(F)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F12 compound treatment 1455647.0 725000.0 1.54 1905982.0 1160000.0 2.64 2.9538 0.9669 1985554 ChemDiv2_003994 CCSc1ncnc2sc3CCCCc3c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F13 compound treatment 1452061.0 721000.0 1.53 1521231.0 777000.0 1.77 2.3299 0.9974 1308916 ChemDiv2_003995 COc1cccc(OCC(=O)N2CCN(C)CC2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F14 compound treatment 1143094.0 413000.0 0.87 2208480.0 1460000.0 3.33 2.9716 0.8636 1930247 ChemDiv2_003996 Cc1nc2n(ncc2c(=O)n1CC=C)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F15 compound treatment 1332720.0 602000.0 1.28 1487511.0 743000.0 1.69 2.0968 0.9905 1559847 ChemDiv2_003997 COc1cc(ccc1O)C2CC(=O)NC(=C2C#N)SCC(=O)NCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F16 compound treatment 1001120.0 271000.0 0.57 1533381.0 789000.0 1.79 1.6735 0.8889 1871050 ChemDiv2_003998 COc1cccc(c1)C2C3=C(Nc4c2c(=O)n(C)c(=O)n4C)c5ccccc5C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F17 compound treatment 1010913.0 280000.0 0.59 1520226.0 776000.0 1.76 1.667 0.8959 1145453 ChemDiv2_003999 COC(=O)c1ccc(cc1)C(=O)Nc2ccccc2c3nc4ccccc4[nH]3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F18 compound treatment 1189412.0 459000.0 0.97 1538008.0 793000.0 1.8 1.9632 0.958 1985555 ChemDiv2_004000 CCOC(=O)CN1C(=O)C2CC=C(Cl)CC2C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F19 compound treatment 1128696.0 398000.0 0.84 1328584.0 584000.0 1.33 1.5355 0.9761 1985556 ChemDiv2_004001 COc1ccccc1N(CC(=O)Nc2ccc(Oc3ccccc3)cc2)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F20 compound treatment 966909.0 236000.0 0.5 1416297.0 672000.0 1.53 1.434 0.8923 1985557 ChemDiv2_004002 CC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)Nc4ccccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F21 compound treatment 930401.0 200000.0 0.42 1289975.0 545000.0 1.24 1.1761 0.8978 1985558 ChemDiv2_004003 O=C(Nc1cccc(c1)c2nc3ccccc3s2)c4nc[nH]n4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F22 compound treatment 1019326.0 289000.0 0.61 1154304.0 410000.0 0.93 1.0913 0.9793 1454699 ChemDiv2_004004 Cc1ccc2ccc(C(Nc3ccccn3)c4ccc5OCOc5c4)c(O)c2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F23 mock treatment 1192180.0 462000.0 0.98 1121138.0 376000.0 0.86 1.2971 0.9978 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 F24 mock treatment 627142.0 -103000.0 -0.22 490203.0 -255000.0 -0.58 -0.5642 -0.9118 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G01 compound treatment 931186.0 201000.0 0.43 911627.0 167000.0 0.38 0.5691 0.9984 1688675 ChemDiv2_004005 CC(Nc1nc(c2ccccc2)c3cc(C)ccc3n1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G02 compound treatment 783808.0 53200.0 0.11 1016863.0 272000.0 0.62 0.5173 0.8225 1985559 ChemDiv2_004006 Nc1nc(N)n(n1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G03 compound treatment 925156.0 195000.0 0.41 1351245.0 607000.0 1.38 1.2668 0.8801 1342611 ChemDiv2_004007 CCCOC(=O)c1ccc(cc1)N2COc3ccc4c(C)cc(=O)oc4c3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G04 compound treatment 907323.0 177000.0 0.37 1056683.0 312000.0 0.71 0.7665 0.9555 1985560 ChemDiv2_004008 CCN(CC)c1ncnc2sc3CC(CCc3c12)(C#N)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G05 compound treatment 918492.0 188000.0 0.4 1098848.0 354000.0 0.81 0.851 0.9474 1985561 ChemDiv2_004009 CCc1nnc(SCC(=O)N)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G06 compound treatment 1061087.0 331000.0 0.7 1191344.0 447000.0 1.02 1.2135 0.9836 1179519 ChemDiv2_004010 Cn1c(=O)n(C)c2nc(N3CCCCC3)n(CCCc4ccccc4)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G07 compound treatment 1056944.0 326000.0 0.69 1218191.0 473000.0 1.08 1.2504 0.9772 1415482 ChemDiv2_004011 Oc1ccc2oc(cc(=O)c2c1)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G08 compound treatment 1152201.0 422000.0 0.89 1249267.0 505000.0 1.15 1.4432 0.9924 1788140 ChemDiv2_004012 Cc1n[nH]c(=O)nc1NCC2CCCO2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G09 compound treatment 1004942.0 274000.0 0.58 1425177.0 680000.0 1.55 1.5052 0.9107 1492417 ChemDiv2_004013 OCCN1CCN(CC1)C(=O)CSc2nc3sc4CCCc4c3c(=O)n2CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G10 compound treatment 1244975.0 514000.0 1.09 1555194.0 810000.0 1.84 2.0741 0.9687 1985562 ChemDiv2_004014 Cc1ccc2nc([nH]c2c1)c3cc4ccccc4oc3=N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G11 compound treatment 1175864.0 445000.0 0.94 1816614.0 1070000.0 2.44 2.3908 0.9148 1610332 ChemDiv2_004015 CCC1CC(C)(OC1=O)c2csc(Nc3ccccc3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G12 compound treatment 1052758.0 322000.0 0.68 1325594.0 581000.0 1.32 1.4168 0.9529 1474699 ChemDiv2_004016 Cc1ccc2nc(C)cc(N3CCOCC3)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G13 compound treatment 1092492.0 362000.0 0.77 1593988.0 849000.0 1.93 1.9079 0.9183 1499074 ChemDiv2_004017 CS(=O)(=O)N1CCN(CCCc2ccccc2)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G14 compound treatment 1243324.0 513000.0 1.09 2037874.0 1290000.0 2.94 2.8476 0.9084 1421194 ChemDiv2_004018 OC(=O)c1ccc(Nc2ncnc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G15 compound treatment 982754.0 252000.0 0.53 2116469.0 1370000.0 3.12 2.5833 0.8164 1381460 ChemDiv2_004019 CCOC(=O)Cc1csc(NC(=O)CN2C(=O)c3ccccc3C2=O)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G16 compound treatment 956401.0 226000.0 0.48 1876456.0 1130000.0 2.57 2.158 0.8245 1344892 ChemDiv2_004020 Cc1nnc2n(C3CCCCC3)c(=O)c4c5CCCc5sc4n12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G17 compound treatment 1102507.0 372000.0 0.79 1715384.0 971000.0 2.21 2.118 0.9038 1231822 ChemDiv2_004021 Nc1c(C#N)c2nc3ccccc3nc2n1C4CCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G18 compound treatment 1040146.0 310000.0 0.66 1627973.0 883000.0 2.01 1.884 0.8918 1450839 ChemDiv2_004022 CCN(CC)CCN1C(C(=C(O)C1=O)C(=O)c2ccc(cc2)S(=O)(=O)N3CCOCC3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G19 compound treatment 1006683.0 276000.0 0.59 1303165.0 558000.0 1.27 1.3117 0.9382 1695689 ChemDiv2_004023 CCN(CC)c1ncnc2c3ccccc3[nH]c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G20 compound treatment 1029110.0 299000.0 0.63 1282034.0 537000.0 1.22 1.3114 0.9531 1470992 ChemDiv2_004024 COC(=O)C(C)Oc1ccc2cc(c3nc4ccccc4s3)c(=O)oc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G21 compound treatment 952206.0 222000.0 0.47 1273408.0 529000.0 1.2 1.1822 0.916 1985563 ChemDiv2_004025 OC(=O)C1C2OC3(CN(C(=O)C13)c4ccccc4)C=C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G22 compound treatment 1019041.0 288000.0 0.61 1091460.0 347000.0 0.79 0.9899 0.9921 1648286 ChemDiv2_004026 O=C(Oc1cccc2cccnc12)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G23 mock treatment 954388.0 224000.0 0.47 1075591.0 331000.0 0.75 0.8675 0.9753 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 G24 mock treatment 854142.0 124000.0 0.26 598792.0 -146000.0 -0.33 -0.0493 -0.1167 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H01 compound treatment 685403.0 -45200.0 -0.1 653827.0 -90900.0 -0.21 -0.2138 -0.9388 1363433 ChemDiv2_004027 CCOC(=O)Nc1sc(NS(=O)(=O)c2ccc(C)cc2)nc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H02 compound treatment 1144117.0 414000.0 0.88 1071133.0 326000.0 0.74 1.1447 0.9966 1297191 ChemDiv2_004028 CC(=O)NS(=O)(=O)c1ccc(NC(=O)c2c(C)onc2c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H03 compound treatment 1162085.0 432000.0 0.91 1099519.0 355000.0 0.81 1.2173 0.998 1128100 ChemDiv2_004029 O=C(Nc1cccc(c1)c2nc3ncccc3o2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H04 compound treatment 1195621.0 465000.0 0.99 1058360.0 314000.0 0.71 1.2014 0.9874 1641552 ChemDiv2_004030 OC(=O)C(Cc1ccccc1)N2C(=O)C3C4CC(C=C4)C3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H05 compound treatment 1002417.0 272000.0 0.58 1120437.0 376000.0 0.85 1.0115 0.9816 1343091 ChemDiv2_004031 CC(C(=O)c1ccccc1)C2(O)C(=O)N(CCc3ccccc3)c4ccccc42 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H06 compound treatment 1165943.0 435000.0 0.92 1219054.0 474000.0 1.08 1.4152 0.997 1985564 ChemDiv2_004032 CCOC(=O)C(C1CCCCC1)C(=O)N2CCN(C)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H07 compound treatment 1175453.0 445000.0 0.94 1506602.0 762000.0 1.73 1.8917 0.9592 1083393 ChemDiv2_004033 CSc1nsc(SC)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H08 compound treatment 1032017.0 301000.0 0.64 1545405.0 801000.0 1.82 1.7391 0.9014 1985565 ChemDiv2_004034 O=C(Nc1nncs1)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H09 compound treatment 1214615.0 484000.0 1.03 1126589.0 382000.0 0.87 1.3395 0.9965 1985566 ChemDiv2_004035 CCOC(=O)CSc1nnc(o1)c2ccc(cc2)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H10 compound treatment 1326125.0 596000.0 1.26 1057814.0 313000.0 0.71 1.3961 0.9632 1985567 ChemDiv2_004036 CC(=O)Oc1ccc(cc1)C(=O)Nc2cc(ccc2C)c3nc4ccccc4[nH]3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H11 compound treatment 1260246.0 530000.0 1.12 1955282.0 1210000.0 2.75 2.7402 0.9218 1394912 ChemDiv2_004037 O=C(C1CCCNC1=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H12 compound treatment 1215446.0 485000.0 1.03 1971690.0 1230000.0 2.79 2.6994 0.908 1985568 ChemDiv2_004038 C=CCSc1ncnc2sc3CCCCc3c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H13 compound treatment 1256869.0 526000.0 1.12 1011634.0 267000.0 0.61 1.2181 0.959 1516589 ChemDiv2_004039 COc1ccccc1C(=O)Nc2nc3ccccc3n2CCOc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H14 compound treatment 1180277.0 450000.0 0.95 1767102.0 1020000.0 2.32 2.3178 0.9225 1938255 ChemDiv2_004040 O=c1oc(nc2sc3CCCCc3c12)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H15 compound treatment 1222929.0 492000.0 1.04 1093790.0 349000.0 0.79 1.2993 0.9909 1339554 ChemDiv2_004041 CCOC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccc4C(=O)NC(=O)c4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H16 compound treatment 1120978.0 390000.0 0.83 1145881.0 401000.0 0.91 1.2302 0.9988 1985569 ChemDiv2_004042 Cc1ccc(cc1)c2nc(no2)c3cccc(C)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H17 compound treatment 1241506.0 511000.0 1.08 1023589.0 279000.0 0.63 1.2143 0.9675 1222479 ChemDiv2_004043 CCOc1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC(=O)Nc3cccc(OC)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H18 compound treatment 1138472.0 408000.0 0.86 1891331.0 1150000.0 2.61 2.4548 0.8938 1502222 ChemDiv2_004044 COc1cc(cc(OC)c1OC)c2nnc(SC(=O)OCc3ccccc3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H19 compound treatment 1069744.0 339000.0 0.72 1614468.0 870000.0 1.98 1.9067 0.9062 1985570 ChemDiv2_004045 CCOc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccc(CC#N)cc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H20 compound treatment 952306.0 222000.0 0.47 1304480.0 560000.0 1.27 1.2323 0.9083 1985571 ChemDiv2_004046 CC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)Nc4ccccc4O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H21 compound treatment 853644.0 123000.0 0.26 1181179.0 436000.0 0.99 0.8862 0.8637 1240358 ChemDiv2_004047 CCc1ccc(Oc2coc3cc(OC(=O)OC)ccc3c2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H22 compound treatment 820344.0 89800.0 0.19 1191837.0 447000.0 1.02 0.8534 0.8252 1393349 ChemDiv2_004048 C(Sc1nnc-2c(OC(Nc3ccccc32)c4ccncc4)n1)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H23 mock treatment 792089.0 61500.0 0.13 1103151.0 358000.0 0.81 0.6685 0.81 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 H24 mock treatment 672573.0 -58000.0 -0.12 698563.0 -46200.0 -0.1 -0.1611 -0.9969 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I01 compound treatment 721889.0 -8670.0 -0.02 702615.0 -42100.0 -0.1 -0.0807 -0.8278 1264064 ChemDiv2_004049 O=C(NCc1ccccc1)C2CN(C(=O)C2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I02 compound treatment 830938.0 100000.0 0.21 1128568.0 384000.0 0.87 0.7676 0.8545 1985572 ChemDiv2_004050 CC(=O)Nc1nc(N)n(n1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I03 compound treatment 1130204.0 400000.0 0.85 1227557.0 483000.0 1.1 1.3753 0.9918 1630449 ChemDiv2_004051 COC(=O)c1cccc(c1)N2COc3ccc4c5CCCc5c(=O)oc4c3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I04 compound treatment 974000.0 243000.0 0.52 1162260.0 418000.0 0.95 1.0362 0.959 1333763 ChemDiv2_004052 CCN(CC)c1nc(nc2ccccc12)c3ccccc3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I05 compound treatment 855033.0 124000.0 0.26 1116451.0 372000.0 0.85 0.7842 0.8857 1935272 ChemDiv2_004053 CCOc1cccc(=O)c2c(C)oc(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I06 compound treatment 1170813.0 440000.0 0.93 1235464.0 491000.0 1.12 1.4489 0.9961 1474130 ChemDiv2_004054 CCn1c(NC)nc2n(C)c(=O)n(C)c(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I07 compound treatment 1195267.0 465000.0 0.99 1381210.0 636000.0 1.45 1.7199 0.9824 1172205 ChemDiv2_004055 O=C(Nc1ncnc2sc3CCCc3c12)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I08 compound treatment 1145709.0 415000.0 0.88 1516401.0 772000.0 1.75 1.8629 0.9491 1985573 ChemDiv2_004056 CCCCN(CC)c1ncnc2ccc(C)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I09 compound treatment 998256.0 268000.0 0.57 1474492.0 730000.0 1.66 1.5745 0.8979 1985574 ChemDiv2_004057 N#CC1(CCc2c(C1)sc3ncnc(N4CCCC4)c23)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I10 compound treatment 1104288.0 374000.0 0.79 1449919.0 705000.0 1.6 1.6939 0.9472 1577289 ChemDiv2_004058 CC(C1C(=C(N)OC2=C1C(=O)CC(C)(C)C2)C#N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I11 compound treatment 905196.0 175000.0 0.37 1685956.0 941000.0 2.14 1.775 0.8173 1248301 ChemDiv2_004059 CCCSc1nc2ccccc2c(=O)n1C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I12 compound treatment 1079993.0 349000.0 0.74 1804000.0 1060000.0 2.41 2.2268 0.8837 1985575 ChemDiv2_004060 Cc1ccc2nc(C)cc(NCC=C)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I13 compound treatment 939019.0 208000.0 0.44 1336369.0 592000.0 1.35 1.2637 0.8925 1315107 ChemDiv2_004061 CCc1ccc(CN2CCN(CC2)C(=O)Cc3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I14 compound treatment 1021424.0 291000.0 0.62 1861519.0 1120000.0 2.54 2.2314 0.854 1581829 ChemDiv2_004062 O=C(NCCN1CCOCC1)c2cc3ccccc3oc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I15 compound treatment 1266630.0 536000.0 1.14 1145576.0 401000.0 0.91 1.448 0.994 1637910 ChemDiv2_004063 OC(=O)c1ccc2NC(C3CC=CC3c2c1)c4ccc(Br)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I16 compound treatment 1089802.0 359000.0 0.76 1880047.0 1140000.0 2.58 2.3637 0.8783 1281521 ChemDiv2_004064 Clc1ccc2nc(oc(=O)c2c1)c3ccc4C(=O)N(CC5CCCO5)C(=O)c4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I17 compound treatment 995829.0 265000.0 0.56 1532329.0 788000.0 1.79 1.6638 0.8865 1985576 ChemDiv2_004065 O=C(COC(=O)c1cccc(NS(=O)(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)c1)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I18 compound treatment 1114454.0 384000.0 0.81 1503114.0 758000.0 1.72 1.7947 0.9413 1563751 ChemDiv2_004066 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I19 compound treatment 912884.0 182000.0 0.39 1306144.0 561000.0 1.28 1.1759 0.8817 1679216 ChemDiv2_004067 CCOCc1cnc(C)nc1NCC(=O)c2c(C)n(C)c3ccc(OC)cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I20 compound treatment 1008751.0 278000.0 0.59 1280616.0 536000.0 1.22 1.2786 0.9445 1315726 ChemDiv2_004068 COc1ccc(CCNc2nnc(c3ccccc3)c(=O)[nH]2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I21 compound treatment 1012981.0 282000.0 0.6 1251822.0 507000.0 1.15 1.2386 0.9534 1560002 ChemDiv2_004069 O=C(CC1SC(=O)NC1=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I22 compound treatment 882957.0 152000.0 0.32 1154142.0 409000.0 0.93 0.8867 0.8999 1247513 ChemDiv2_004070 CCCCS(=O)c1sc2nc(C)cc(C)c2c1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I23 mock treatment 860010.0 129000.0 0.27 1172547.0 428000.0 0.97 0.8818 0.8725 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 I24 mock treatment 743675.0 13100.0 0.03 825875.0 81200.0 0.18 0.1501 0.8046 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J01 compound treatment 698252.0 -32300.0 -0.07 737177.0 -7540.0 -0.02 -0.0606 -0.8576 1636508 ChemDiv2_004071 O=c1[nH]c2ccccc2nc1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J02 compound treatment 868408.0 138000.0 0.29 1116133.0 371000.0 0.84 0.8037 0.8995 1574560 ChemDiv2_004072 Fc1ccc(NC(=O)C2CCC(CC2)N3C(=O)C4C5CC(C=C5)C4C3=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J03 compound treatment 845279.0 115000.0 0.24 1116367.0 372000.0 0.84 0.7694 0.8751 1603978 ChemDiv2_004073 O=C(COc1ccccc1)Nc2cccc(c2)c3nc4ncccc4o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J04 compound treatment 953345.0 223000.0 0.47 1194236.0 450000.0 1.02 1.0566 0.9385 1985577 ChemDiv2_004074 CC1(C)Cc2c(C#N)c(sc2CO1)N3C(=O)C4CC=C(Cl)CC4C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J05 compound treatment 954232.0 224000.0 0.47 1266794.0 522000.0 1.19 1.1746 0.919 1385447 ChemDiv2_004075 CCOC(=O)C1C2C(C)C(C)(NC1=O)Oc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J06 compound treatment 1122088.0 392000.0 0.83 1277853.0 533000.0 1.21 1.444 0.9829 1985578 ChemDiv2_004076 CCOC(=O)C(Cc1ccccc1)C(=O)N2CCN(C)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J07 compound treatment 1061728.0 331000.0 0.7 1351321.0 607000.0 1.38 1.4716 0.9509 1985579 ChemDiv2_004077 CCCOC(=O)CN1C(=O)c2ccc(Br)cc2C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J08 compound treatment 1088366.0 358000.0 0.76 1374102.0 629000.0 1.43 1.5482 0.9559 1258167 ChemDiv2_004078 OC(=O)c1cc(C(=O)O)c2cc(Cl)ccc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J09 compound treatment 1000384.0 270000.0 0.57 1509907.0 765000.0 1.74 1.6346 0.8926 1788728 ChemDiv2_004079 NCCOC(=O)Nc1nc2ccccc2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J10 compound treatment 1076029.0 345000.0 0.73 1489450.0 745000.0 1.69 1.7151 0.9297 1583260 ChemDiv2_004080 CC(Sc1nc2ccccc2n1Cc3ccccc3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J11 compound treatment 1004071.0 274000.0 0.58 1747045.0 1000000.0 2.28 2.0214 0.8596 1559143 ChemDiv2_004081 CC(C)NCC(O)COc1ccc2[nH]cc(CCNC(=O)C)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J12 compound treatment 1460952.0 730000.0 1.55 1728294.0 984000.0 2.24 2.6761 0.9839 1985580 ChemDiv2_004082 CC1CCc2c(C1)sc3ncnc(SCC=C)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J13 compound treatment 1348802.0 618000.0 1.31 1604605.0 860000.0 1.95 2.3092 0.9811 1245318 ChemDiv2_004083 CCOC(=O)c1c(CSC#N)oc2ccc(OC(=O)C)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J14 compound treatment 1314719.0 584000.0 1.24 1395901.0 651000.0 1.48 1.9225 0.9961 1460387 ChemDiv2_004084 CCOC(=O)c1cnc2c(ccc3ccccc32)c1NCc4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J15 compound treatment 1216545.0 486000.0 1.03 1482839.0 738000.0 1.68 1.9151 0.9726 1371985 ChemDiv2_004085 CC1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc-4c(COc5ccccc45)s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J16 compound treatment 1214889.0 484000.0 1.03 1771997.0 1030000.0 2.34 2.3775 0.9319 1121878 ChemDiv2_004086 COC(=O)c1cn(C(=O)c2cccs2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J17 compound treatment 1071807.0 341000.0 0.72 1556377.0 812000.0 1.85 1.8164 0.9164 1599498 ChemDiv2_004087 CC(O)CSc1nc2n(C)c(=O)[nH]c(=O)c2n1CC(=C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J18 compound treatment 989414.0 259000.0 0.55 1407125.0 662000.0 1.51 1.4529 0.9065 1985581 ChemDiv2_004088 OC(=O)CCC(=O)Nc1nc2NC(=CC(c3ccccc3)n2n1)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J19 compound treatment 1048692.0 318000.0 0.67 1260899.0 516000.0 1.17 1.3067 0.9654 1985582 ChemDiv2_004089 Clc1ccc(NC(=O)OCN2C(=O)c3ccccc3C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J20 compound treatment 939583.0 209000.0 0.44 1363568.0 619000.0 1.41 1.3082 0.8869 1985583 ChemDiv2_004090 CCCc1nnc(NC(=O)C(C)N2C(=O)C3C4CC(C=C4)C3C2=O)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J21 compound treatment 857781.0 127000.0 0.27 1185858.0 441000.0 1.0 0.8999 0.8665 1738660 ChemDiv2_004091 CC(=O)Oc1cccc(Nc2ncnc3ccccc23)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J22 compound treatment 921316.0 191000.0 0.4 1158746.0 414000.0 0.94 0.9516 0.9288 1439414 ChemDiv2_004092 Cc1cccc(NC(c2cccc(OCC=C)c2)c3ccc4cccnc4c3O)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J23 mock treatment 848861.0 118000.0 0.25 988293.0 244000.0 0.55 0.5689 0.9358 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 J24 mock treatment 671194.0 -59400.0 -0.13 796590.0 51900.0 0.12 -0.0056 -0.0325 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K01 compound treatment 498373.0 -232000.0 -0.49 628130.0 -117000.0 -0.27 -0.5355 -0.9578 1787231 ChemDiv2_004093 CCn1c(NCc2ccccc2O)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K02 compound treatment 1071568.0 341000.0 0.72 1016401.0 272000.0 0.62 0.948 0.9969 1944426 ChemDiv2_004094 CSc1nnc(c2ccccc2)c(n1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K03 compound treatment 1112587.0 382000.0 0.81 1071570.0 327000.0 0.74 1.0981 0.9991 1985584 ChemDiv2_004095 Cc1nnc2c3c(csc3ncn12)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K04 compound treatment 804728.0 74200.0 0.16 848533.0 104000.0 0.24 0.2781 0.9805 1985585 ChemDiv2_004096 CCCOc1ccc(cc1)c2nc(NCCN)c3ccccc3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K05 compound treatment 946959.0 216000.0 0.46 1064161.0 319000.0 0.73 0.8379 0.9755 1181297 ChemDiv2_004097 CCOc1cc(cc(=O)c2c(C)oc(C)c12)c3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K06 compound treatment 1197549.0 467000.0 0.99 1203293.0 459000.0 1.04 1.4373 0.9997 1337936 ChemDiv2_004098 Cn1c(=O)n(C)c2nc(NCC=C)n(Cc3ccc(F)cc3)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K07 compound treatment 1033100.0 303000.0 0.64 1108380.0 364000.0 0.83 1.0382 0.9921 1985586 ChemDiv2_004099 Brc1cnc2[nH]c(SCc3ccccc3C#N)nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K08 compound treatment 1243782.0 513000.0 1.09 1169259.0 425000.0 0.97 1.4519 0.9982 1364518 ChemDiv2_004100 CC1(C)Cc2c(CO1)sc3nc([nH]c(=O)c23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K09 compound treatment 1064835.0 334000.0 0.71 1275784.0 531000.0 1.21 1.3549 0.9678 1625468 ChemDiv2_004101 COc1cc(cc(OC)c1OC)C2C3=C(CC(C)(C)CC3=O)Nc4[nH]c(=O)[nH]c(=O)c24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K10 compound treatment 926456.0 196000.0 0.42 1375815.0 631000.0 1.43 1.3082 0.8758 1200092 ChemDiv2_004102 CCOC(=O)CSC1=C(C#N)C(CC(=O)N1)c2ccc3OCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K11 compound treatment 1012355.0 282000.0 0.6 1614553.0 870000.0 1.98 1.8208 0.8814 1311236 ChemDiv2_004103 CSc1nc2ccccc2c(=O)n1CC3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K12 compound treatment 1131764.0 401000.0 0.85 1708004.0 963000.0 2.19 2.15 0.9151 1677229 ChemDiv2_004104 CCCCN(C)Cc1c(O)ccc2c(cc(=O)oc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K13 compound treatment 1029856.0 299000.0 0.63 1526844.0 782000.0 1.78 1.706 0.9036 1285445 ChemDiv2_004105 CC(C)N1CCN(CC1)C(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K14 compound treatment 1167643.0 437000.0 0.93 1805909.0 1060000.0 2.41 2.3612 0.9136 1140828 ChemDiv2_004106 O=C1CC(c2ccccc2)n3ncnc3N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K15 compound treatment 1031897.0 301000.0 0.64 1474836.0 730000.0 1.66 1.6255 0.9139 1523696 ChemDiv2_004107 CCCn1c(NC(=O)C2CCCCC2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K16 compound treatment 1146767.0 416000.0 0.88 1387774.0 643000.0 1.46 1.6577 0.9708 1720633 ChemDiv2_004108 CCCOc1cccc(c1)c2nc3ccccc3c(=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K17 compound treatment 982236.0 252000.0 0.53 1384655.0 640000.0 1.45 1.4061 0.9073 1985587 ChemDiv2_004109 Cc1ccc(cc1)S(=O)(=O)CCc2nc3ccccc3n2CC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K18 compound treatment 1280919.0 550000.0 1.17 1262319.0 518000.0 1.18 1.6571 1.0 1985588 ChemDiv2_004110 CCN(CC)CCSc1nc2ccccc2c(=O)n1c3ccc(OC)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K19 compound treatment 1211072.0 481000.0 1.02 1206956.0 462000.0 1.05 1.4634 0.9999 1422263 ChemDiv2_004111 Cc1[nH]c2cc(C)ccc2c1C(=O)CNc3nccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K20 compound treatment 1122265.0 392000.0 0.83 1161102.0 416000.0 0.95 1.2566 0.9979 1507069 ChemDiv2_004112 Cc1n[nH]c(=O)nc1NCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K21 compound treatment 1099340.0 369000.0 0.78 1214793.0 470000.0 1.07 1.3085 0.9882 1295730 ChemDiv2_004113 Oc1ccc(NC(=O)CC2SC(=O)NC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K22 compound treatment 984974.0 254000.0 0.54 1084103.0 339000.0 0.77 0.927 0.9847 1414391 ChemDiv2_004114 CCCCS(=O)c1sc2nc3CCCCc3cc2c1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K23 mock treatment 920694.0 190000.0 0.4 936860.0 192000.0 0.44 0.5939 0.9992 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 K24 mock treatment 609349.0 -121000.0 -0.26 580149.0 -165000.0 -0.37 -0.4463 -0.9832 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L01 compound treatment 539934.0 -191000.0 -0.4 647403.0 -97300.0 -0.22 -0.4422 -0.9598 1585607 ChemDiv2_004115 CC(=O)n1c2C(=O)CCCc2c3cc(C)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L02 compound treatment 795950.0 65400.0 0.14 973571.0 229000.0 0.52 0.4659 0.8653 1985589 ChemDiv2_004116 COC(=O)c1ccc(C)c(NC(=O)c2ccc(cc2)C3SCC(=O)N3Cc4ccccc4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L03 compound treatment 853386.0 123000.0 0.26 1026404.0 282000.0 0.64 0.637 0.9214 1647651 ChemDiv2_004117 CC(C)CC(=O)Nc1cc(ccc1C)c2nc3ncccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L04 compound treatment 948964.0 218000.0 0.46 1037019.0 292000.0 0.66 0.7973 0.9844 1985590 ChemDiv2_004118 OC(=O)C1CC=C(Cl)CC1C(=O)NCC2OCCc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L05 compound treatment 958381.0 228000.0 0.48 997741.0 253000.0 0.58 0.7483 0.9962 1507006 ChemDiv2_004119 CSc1nc(SC)c2c3CCN(C)Cc3sc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L06 compound treatment 1041772.0 311000.0 0.66 1034749.0 290000.0 0.66 0.9328 1.0 1781197 ChemDiv2_004120 O=C1C2ON(C(C2C(=O)N1Cc3ccccc3)c4ccco4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L07 compound treatment 932639.0 202000.0 0.43 1078973.0 334000.0 0.76 0.8403 0.9632 1332115 ChemDiv2_004121 CC(C)(C)C1CCc2c(C(=O)N3CCCC3)c(NC(=O)c4ccco4)sc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L08 compound treatment 995446.0 265000.0 0.56 1134514.0 390000.0 0.89 1.0237 0.9758 1985591 ChemDiv2_004122 Fc1cccc2C3C=CCC3C(Nc12)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L09 compound treatment 940852.0 210000.0 0.45 1180458.0 436000.0 0.99 1.0158 0.935 1985592 ChemDiv2_004123 CCCCc1nnc(SCC(=O)Nc2ncccn2)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L10 compound treatment 964668.0 234000.0 0.5 1177803.0 433000.0 0.98 1.0472 0.9497 1469291 ChemDiv2_004124 OC(=O)Cn1c(SC2CCCCC2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L11 compound treatment 1026260.0 296000.0 0.63 1299245.0 555000.0 1.26 1.3347 0.948 1316454 ChemDiv2_004125 COc1ccc2c(CCN)c[nH]c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L12 compound treatment 1132826.0 402000.0 0.85 1496596.0 752000.0 1.71 1.8118 0.9484 1213639 ChemDiv2_004126 OCCN1CCN(CC1)c2ncnc3ccc(Br)cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L13 compound treatment 1094422.0 364000.0 0.77 1278518.0 534000.0 1.21 1.4036 0.9761 1257376 ChemDiv2_004127 CNc1nc2n(C)c(=O)n(C)c(=O)c2n1CC(O)COc3ccccc3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L14 compound treatment 1185410.0 455000.0 0.96 1630769.0 886000.0 2.01 2.1063 0.9431 1360890 ChemDiv2_004128 CCOC(=O)c1cnc2c(C)c(Cl)ccc2c1N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L15 compound treatment 1047819.0 317000.0 0.67 1315783.0 571000.0 1.3 1.3937 0.9531 1985593 ChemDiv2_004129 Cc1cc(C)nc(SCc2n[nH]c(=S)o2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L16 compound treatment 1167459.0 437000.0 0.93 1252490.0 508000.0 1.15 1.4712 0.994 1985594 ChemDiv2_004130 Clc1ccc(CC(=O)Nc2nc[nH]n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L17 compound treatment 1084571.0 354000.0 0.75 1256778.0 512000.0 1.16 1.3539 0.9774 1665366 ChemDiv2_004131 Cc1cccc(Cn2c(SCC=C)nc3n(C)c(=O)n(C)c(=O)c23)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L18 compound treatment 1148238.0 418000.0 0.89 1296658.0 552000.0 1.25 1.5134 0.9854 1985595 ChemDiv2_004132 CCCC(=O)Nc1nc2NC(=CC(c3ccccc3)n2n1)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L19 compound treatment 1049168.0 319000.0 0.68 1164942.0 420000.0 0.96 1.1532 0.9856 1656195 ChemDiv2_004133 CC(C)Nc1nc(NC(C)C)nc(OCC=C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L20 compound treatment 952067.0 222000.0 0.47 1133776.0 389000.0 0.88 0.9575 0.9561 1985596 ChemDiv2_004134 OC(Cn1c(=N)n(CC=C)c2ccccc12)c3cccc(Br)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L21 compound treatment 941185.0 211000.0 0.45 1053934.0 309000.0 0.7 0.8128 0.976 1329450 ChemDiv2_004135 COc1cc(cc(OC)c1OC)C(=O)Oc2cccc(Nc3ncnc4ccccc34)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L22 compound treatment 906666.0 176000.0 0.37 1034706.0 290000.0 0.66 0.7302 0.9637 1426441 ChemDiv2_004136 COC(=O)c1ccc(cc1)C(Nc2ccccn2)c3ccc4ccc(C)nc4c3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L23 mock treatment 840270.0 110000.0 0.23 809692.0 65000.0 0.15 0.2689 0.976 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 L24 mock treatment 609668.0 -121000.0 -0.26 540716.0 -204000.0 -0.46 -0.5092 -0.9609 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M01 compound treatment 457343.0 -273000.0 -0.58 613022.0 -132000.0 -0.3 -0.6213 -0.9529 1787236 ChemDiv2_004137 Cn1c(NCc2cc(Cl)ccc2O)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M02 compound treatment 763828.0 33300.0 0.07 971806.0 227000.0 0.52 0.4149 0.7963 1985597 ChemDiv2_004138 CC(=C)Cn1c(SCC=C)nc2ccccc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M03 compound treatment 843897.0 113000.0 0.24 1051500.0 307000.0 0.7 0.6631 0.8989 1246133 ChemDiv2_004139 CCC(CO)Nc1nc(C)nc2sc3CCCc3c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M04 compound treatment 909351.0 179000.0 0.38 994272.0 250000.0 0.57 0.6692 0.9808 1985598 ChemDiv2_004140 COC(=O)CNc1nc(nc2ccccc12)c3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M05 compound treatment 878869.0 148000.0 0.31 1108883.0 364000.0 0.83 0.8078 0.9121 1659336 ChemDiv2_004141 CCOc1cc(cc(=O)c2c(C)oc(C)c12)c3ccc(O)c(O)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M06 compound treatment 948841.0 218000.0 0.46 1108738.0 364000.0 0.83 0.9124 0.9623 1521556 ChemDiv2_004142 COc1ccc(OCC(O)Cn2c(nc3n(C)c(=O)n(C)c(=O)c23)N(C)C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M07 compound treatment 909120.0 179000.0 0.38 1096655.0 352000.0 0.8 0.8335 0.9416 1852545 ChemDiv2_004143 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(F)cc3)C(=O)Nc4ccc(F)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M08 compound treatment 989597.0 259000.0 0.55 1136209.0 391000.0 0.89 1.0177 0.9731 1711439 ChemDiv2_004144 Cn1c(NCc2ccccc2)nc3n(C)c(=O)n(C)c(=O)c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M09 compound treatment 909306.0 179000.0 0.38 1168530.0 424000.0 0.96 0.9493 0.9168 1941082 ChemDiv2_004145 Nc1cc(O)nc(SCc2ccccc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M10 compound treatment 983720.0 253000.0 0.54 1122921.0 378000.0 0.86 0.9875 0.9743 1873332 ChemDiv2_004146 Nc1c(sc2[nH]c(=O)c(cc12)C(=O)O)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M11 compound treatment 912955.0 182000.0 0.39 1094820.0 350000.0 0.8 0.8363 0.945 1357607 ChemDiv2_004147 CCSc1nc2ccccc2c(=O)n1CC3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M12 compound treatment 1071070.0 341000.0 0.72 1164033.0 419000.0 0.95 1.1845 0.9906 1283051 ChemDiv2_004148 CCN1CCN(Cc2c(O)ccc3c(=O)c(coc23)c4ccccc4Cl)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M13 compound treatment 887689.0 157000.0 0.33 1230249.0 486000.0 1.1 1.0161 0.8812 1199270 ChemDiv2_004149 CC(C)CC(=O)N1CCN(CC2CCC=CC2)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M14 compound treatment 1010225.0 280000.0 0.59 1108807.0 364000.0 0.83 1.0046 0.9866 1985599 ChemDiv2_004150 OCC(O)Cn1c(SCCSc2nc3ccccc3n2CC(O)CO)nc4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M15 compound treatment 920448.0 190000.0 0.4 1182639.0 438000.0 1.0 0.9887 0.9206 1562625 ChemDiv2_004151 NC(=O)COc1ccc(Nc2nnc(c3ccccc3)c4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M16 compound treatment 881298.0 151000.0 0.32 1135066.0 390000.0 0.89 0.8535 0.9048 1274097 ChemDiv2_004152 CC(C)CCN1C(=O)c2ccc(cc2C1=O)c3nc4ccccc4c(=O)o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M17 compound treatment 975128.0 245000.0 0.52 1093434.0 349000.0 0.79 0.9272 0.9788 1488203 ChemDiv2_004153 CC(=O)Nc1nnc(SCC(=O)c2ccccc2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M18 compound treatment 1136529.0 406000.0 0.86 1137208.0 392000.0 0.89 1.2395 0.9998 1209322 ChemDiv2_004154 CN(C)Cc1c(O)ccc2cc(c3nc4ccccc4s3)c(=O)oc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M19 compound treatment 1216937.0 486000.0 1.03 1066485.0 322000.0 0.73 1.2464 0.9859 1247196 ChemDiv2_004155 COc1ccc2n(C)c(C)c(C(=O)CNc3nccs3)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M20 compound treatment 983122.0 253000.0 0.54 1055340.0 311000.0 0.71 0.878 0.9907 1434210 ChemDiv2_004156 CN(C)Cc1c(C)nc2ccccc2c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M21 compound treatment 1104648.0 374000.0 0.79 1077569.0 333000.0 0.76 1.0959 0.9997 1985600 ChemDiv2_004157 CCN(CC)Cc1nc2-c3ccccc3CC4(CCCC4)c2c(=O)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M22 compound treatment 1090409.0 360000.0 0.76 986893.0 242000.0 0.55 0.9288 0.9872 1602483 ChemDiv2_004158 Nc1c(sc2nc3CCCCc3cc12)S(=O)Cc4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M23 mock treatment 986381.0 256000.0 0.54 906577.0 162000.0 0.37 0.6437 0.9822 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 M24 mock treatment 662323.0 -68200.0 -0.14 621666.0 -123000.0 -0.28 -0.3001 -0.9529 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N01 compound treatment 476040.0 -255000.0 -0.54 580729.0 -164000.0 -0.37 -0.6452 -0.9837 1407265 ChemDiv2_004159 Cc1ccc2n(CC(O)CNc3ccccc3)c4C(=O)CCCc4c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N02 compound treatment 990422.0 260000.0 0.55 938919.0 194000.0 0.44 0.7018 0.994 1658265 ChemDiv2_004160 OCCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N03 compound treatment 905377.0 175000.0 0.37 1092568.0 348000.0 0.79 0.8213 0.9403 1985601 ChemDiv2_004161 COC(=O)c1ccc(NC(=O)CN(Cc2ccccc2)S(=O)(=O)c3ccc(OC)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N04 compound treatment 1177962.0 447000.0 0.95 1114762.0 370000.0 0.84 1.2656 0.9982 1582646 ChemDiv2_004162 Cc1cc(C)nc(SCc2nc3ccccc3c(=O)n2c4ccccc4)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N05 compound treatment 256964.0 -474000.0 -1.0 314287.0 -430000.0 -0.98 -1.4019 -0.9999 1985602 ChemDiv2_004163 Cc1cc(NCc2ccccc2)nc(NCc3ccccc3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N06 compound treatment 1345250.0 615000.0 1.3 1187299.0 443000.0 1.01 1.633 0.9918 1592562 ChemDiv2_004164 COc1ccc(cc1O)C2C3C(ON2c4ccccc4)C(=O)N(Cc5ccccc5)C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N07 compound treatment 1054852.0 324000.0 0.69 1182653.0 438000.0 1.0 1.1902 0.9836 1125067 ChemDiv2_004165 Cc1cc(NCc2ccccc2)c3ccccc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N08 compound treatment 1172702.0 442000.0 0.94 1192528.0 448000.0 1.02 1.3827 0.9991 1985603 ChemDiv2_004166 CSc1nnc(c2ccccc2N)c(=O)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N09 compound treatment 1248993.0 518000.0 1.1 1188834.0 444000.0 1.01 1.4911 0.9991 1243491 ChemDiv2_004167 CCCn1c2ccccc2c3nnc(SC(CC)C(=O)Nc4cc(C)on4)nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N10 compound treatment 1255230.0 525000.0 1.11 1257166.0 512000.0 1.17 1.6103 0.9997 1391940 ChemDiv2_004168 Cc1ccc(Nc2nnc(C)c(=O)[nH]2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N11 compound treatment 1223213.0 493000.0 1.04 1285266.0 541000.0 1.23 1.6075 0.9967 1282668 ChemDiv2_004169 CN(C)c1ccnc2sc3c(=O)n(cnc3c12)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N12 compound treatment 1571294.0 841000.0 1.78 1349698.0 605000.0 1.38 2.2329 0.9918 1376108 ChemDiv2_004170 CCC(Oc1ccc2c(c1)oc(=O)c3ccccc32)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N13 compound treatment 1241060.0 510000.0 1.08 1433073.0 688000.0 1.57 1.8719 0.9838 1469143 ChemDiv2_004171 CCCn1c(NC)nc2n(C)c(=O)n(C)c(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N14 compound treatment 1075180.0 345000.0 0.73 1269345.0 525000.0 1.19 1.36 0.9723 1444014 ChemDiv2_004172 COC(=O)Oc1ccc2c(=O)c(Oc3cccc(C)c3)coc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N15 compound treatment 1011420.0 281000.0 0.6 1344995.0 600000.0 1.36 1.3861 0.9309 1985604 ChemDiv2_004173 S=c1[nH]nc(CSc2nc3ccccc3s2)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N16 compound treatment 996838.0 266000.0 0.56 1262147.0 517000.0 1.18 1.231 0.9434 1985605 ChemDiv2_004174 COc1ccc(CC(=O)Nc2nc[nH]n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N17 compound treatment 923489.0 193000.0 0.41 1317830.0 573000.0 1.3 1.2106 0.8864 1788896 ChemDiv2_004175 CSc1ccc(cc1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N18 compound treatment 1019122.0 289000.0 0.61 1304526.0 560000.0 1.27 1.3325 0.9436 1985606 ChemDiv2_004176 O=C(Nc1nc2NC(=CC(c3ccccc3)n2n1)c4ccccc4)c5ccco5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N19 compound treatment 1182835.0 452000.0 0.96 1091864.0 347000.0 0.79 1.2361 0.9953 1490286 ChemDiv2_004177 CCCCc1nc2sc3c(=O)[nH]cnc3c2c4CCCCc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N20 compound treatment 1133123.0 403000.0 0.85 1184512.0 440000.0 1.0 1.3105 0.9969 1985607 ChemDiv2_004178 Cn1c(=O)n(C)c2cn(C3CCCCC3)c(c4ccccc4)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N21 compound treatment 1031923.0 301000.0 0.64 1107134.0 362000.0 0.82 1.0344 0.9921 1123686 ChemDiv2_004179 O=C(Oc1cccc(Nc2ncnc3ccccc23)c1)c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N22 compound treatment 995738.0 265000.0 0.56 1023147.0 278000.0 0.63 0.8451 0.9982 1535427 ChemDiv2_004180 C=CCSc1nnc-2c(OC3(CCCC3)Nc4ccccc42)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N23 mock treatment 811169.0 80600.0 0.17 998461.0 254000.0 0.58 0.5288 0.8788 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 N24 mock treatment 490408.0 -240000.0 -0.51 574296.0 -170000.0 -0.39 -0.634 -0.9909 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O01 compound treatment 470075.0 -260000.0 -0.55 553425.0 -191000.0 -0.43 -0.698 -0.993 1787241 ChemDiv2_004181 CC(Nc1nc2ccccc2n1C)c3cc(Cl)ccc3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O02 compound treatment 762360.0 31800.0 0.07 1013324.0 269000.0 0.61 0.4795 0.7804 1939173 ChemDiv2_004182 CSc1nc(C)cc(n1)n2ccc(=O)[nH]c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O03 compound treatment 880365.0 150000.0 0.32 1142612.0 398000.0 0.9 0.8642 0.9014 1315048 ChemDiv2_004183 OCCNC(=O)c1ccc(CSc2nc3ccccc3c(=O)n2CC=C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O04 compound treatment 878557.0 148000.0 0.31 1213738.0 469000.0 1.07 0.9759 0.8779 1985608 ChemDiv2_004184 COC(=O)c1ccc(Oc2nc(nc3ccccc23)c4cccnc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O05 compound treatment 944032.0 213000.0 0.45 1251432.0 507000.0 1.15 1.1346 0.9167 1308020 ChemDiv2_004185 COc1ccc(cc1)c2cc(=O)c3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O06 compound treatment 920951.0 190000.0 0.4 1356652.0 612000.0 1.39 1.2692 0.8761 1405685 ChemDiv2_004186 Cn1c(=O)n(C)c2[nH]c(=N)c(nc2c1=O)c3nnc4CCCCCn34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O07 compound treatment 974769.0 244000.0 0.52 1287179.0 542000.0 1.23 1.2382 0.9257 1423988 ChemDiv2_004187 CC1=C(C(C2=C(CCCC2=O)N1)c3cccs3)C(=O)Nc4cccc(F)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O08 compound treatment 815665.0 85100.0 0.18 1343039.0 598000.0 1.36 1.0895 0.7939 1939615 ChemDiv2_004188 CCN(CC)c1nc(C)cc(COC)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O09 compound treatment 962186.0 232000.0 0.49 1344816.0 600000.0 1.36 1.312 0.9048 1228828 ChemDiv2_004189 O=C(Oc1ccc2oc(=O)sc2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O10 compound treatment 1033188.0 303000.0 0.64 1480413.0 736000.0 1.67 1.6364 0.9134 1329682 ChemDiv2_004190 NC(=O)CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O11 compound treatment 1003211.0 273000.0 0.58 1389488.0 645000.0 1.47 1.4453 0.9172 1985609 ChemDiv2_004191 CCn1c(SC)nc2ccccc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O12 compound treatment 940977.0 210000.0 0.45 1436751.0 692000.0 1.57 1.428 0.8732 1593808 ChemDiv2_004192 Brc1ccc2ncnc(N3CCOCC3)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O13 compound treatment 951431.0 221000.0 0.47 1353806.0 609000.0 1.38 1.3103 0.8963 1281647 ChemDiv2_004193 CCNc1ccccc1c2nc3ccccc3[nH]c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O14 compound treatment 943593.0 213000.0 0.45 1294018.0 549000.0 1.25 1.2024 0.9054 1432392 ChemDiv2_004194 CCn1c(SCc2nc3ccccc3[nH]2)nc4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O15 compound treatment 1059318.0 329000.0 0.7 1296058.0 551000.0 1.25 1.3792 0.9616 1985610 ChemDiv2_004195 Cc1ccccc1OCCCC(=O)Nc2nc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O16 compound treatment 941824.0 211000.0 0.45 1233925.0 489000.0 1.11 1.1032 0.92 1985611 ChemDiv2_004196 COc1ccccc1OCC(=O)Nc2ccc(cc2)c3nnc(o3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O17 compound treatment 1044453.0 314000.0 0.67 1247947.0 503000.0 1.14 1.2796 0.9667 1933665 ChemDiv2_004197 Cc1cc(O)nc(NCc2ccccc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O18 compound treatment 963435.0 233000.0 0.49 1172163.0 427000.0 0.97 1.0363 0.9507 1288061 ChemDiv2_004198 CCc1cc2c(=O)c(c3nc4ccccc4[nH]3)c(C)oc2cc1OC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O19 compound treatment 1191537.0 461000.0 0.98 1047887.0 303000.0 0.69 1.1784 0.9854 1985612 ChemDiv2_004199 CSc1nc2sc3COC(Cc3c2c(=O)n1c4ccccc4)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O20 compound treatment 1087914.0 357000.0 0.76 1065924.0 321000.0 0.73 1.0521 0.9998 1985613 ChemDiv2_004200 C=CCNc1ncnc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O21 compound treatment 977376.0 247000.0 0.52 999469.0 255000.0 0.58 0.7795 0.9987 1366272 ChemDiv2_004201 Cc1c(NC(=O)c2ccc3OCCOc3c2)cccc1c4nc5ncccc5o4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O22 compound treatment 930165.0 200000.0 0.42 954295.0 210000.0 0.48 0.6361 0.9982 1529850 ChemDiv2_004202 O=C1CCCCC1Sc2nc3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O23 mock treatment 805166.0 74600.0 0.16 813850.0 69100.0 0.16 0.223 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 O24 mock treatment 430854.0 -300000.0 -0.64 457796.0 -287000.0 -0.65 -0.9105 -0.9999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P01 compound treatment 379000.0 -352000.0 -0.75 446685.0 -298000.0 -0.68 -1.0061 -0.9989 1304053 ChemDiv2_004203 CC(C)NCC(O)Cn1c2C(=O)CCCc2c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P02 compound treatment 469694.0 -261000.0 -0.55 509602.0 -235000.0 -0.53 -0.769 -0.9999 1138265 ChemDiv2_004204 COc1ccccc1C2N(CC(C)O)C(=O)C(=C2C(=O)c3ccccc3)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P03 compound treatment 469921.0 -261000.0 -0.55 553925.0 -191000.0 -0.43 -0.6974 -0.9928 1238501 ChemDiv2_004205 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2nccs2)C3CN(C(=O)C3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P04 compound treatment 572678.0 -158000.0 -0.33 603999.0 -141000.0 -0.32 -0.4629 -0.9997 1985614 ChemDiv2_004206 CCOC(=O)N1CCN(CC1)C(=O)CSc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P05 compound treatment 540766.0 -190000.0 -0.4 635875.0 -109000.0 -0.25 -0.4595 -0.9727 1932623 ChemDiv2_004207 CC(=O)N1c2ccccc2C(=CC1(C)C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P06 compound treatment 809544.0 79000.0 0.17 726080.0 -18600.0 -0.04 0.0884 0.512 1661966 ChemDiv2_004208 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)C3COc4ccccc4O3)cc2)nc(C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P07 compound treatment 989039.0 258000.0 0.55 842900.0 98200.0 0.22 0.5453 0.9216 1168548 ChemDiv2_004209 Cc1cc(C)c(NC(=O)C2COc3ccccc3O2)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P08 compound treatment 861438.0 131000.0 0.28 797040.0 52300.0 0.12 0.2803 0.9285 1248403 ChemDiv2_004210 Brc1ccc(cc1)N2CC(CC2=O)C(=O)NCc3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P09 compound treatment 875238.0 145000.0 0.31 888332.0 144000.0 0.33 0.4478 0.9995 1137306 ChemDiv2_004211 CCCc1nc(NC(=O)C)c(C#N)c(c1CC)c2ccccc2OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P10 compound treatment 1035581.0 305000.0 0.65 974461.0 230000.0 0.52 0.8266 0.9944 1985615 ChemDiv2_004212 CCOC(=O)C(C)Sc1ncnc2sc3CCCCc3c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P11 compound treatment 1013627.0 283000.0 0.6 974560.0 230000.0 0.52 0.7938 0.9976 1419811 ChemDiv2_004213 COc1cc(ccc1O)C2N(C(=O)c3[nH]nc(c23)c4ccc(F)cc4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P12 compound treatment 1088624.0 358000.0 0.76 891379.0 147000.0 0.33 0.7725 0.9318 1622871 ChemDiv2_004214 CCCOC(=O)COc1ccc2c(=O)c(coc2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P13 compound treatment 917637.0 187000.0 0.4 892158.0 147000.0 0.34 0.5175 0.9965 1182479 ChemDiv2_004215 CCOC(=O)c1c(C)oc2c1c(C(N3CCN(C)CC3)c4ccccn4)c(O)c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P14 compound treatment 1140541.0 410000.0 0.87 1053091.0 308000.0 0.7 1.1103 0.9943 1985616 ChemDiv2_004216 CSc1nnc(c2ccco2)c(n1)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P15 compound treatment 1189397.0 459000.0 0.97 1135687.0 391000.0 0.89 1.3164 0.999 1690069 ChemDiv2_004217 CC1=C(C(c2ccccc2)c3c(N1)[nH]c(=O)[nH]c3=O)C(=O)OCC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P16 compound treatment 1330593.0 600000.0 1.27 1163403.0 419000.0 0.95 1.5726 0.9898 1184251 ChemDiv2_004218 O=C(CCc1ccccc1)N2CCN(Cc3ccc4OCOc4c3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P17 compound treatment 1154083.0 424000.0 0.9 1098590.0 354000.0 0.8 1.2038 0.9985 1788897 ChemDiv2_004219 COc1ccc(OC)c(c1)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P18 compound treatment 1175824.0 445000.0 0.94 1075624.0 331000.0 0.75 1.1994 0.9937 1570805 ChemDiv2_004220 C(CN1CCOCC1)Nc2ncnc3scc(c4ccccc4)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P19 compound treatment 999272.0 269000.0 0.57 809812.0 65100.0 0.15 0.5075 0.8622 1985617 ChemDiv2_004221 CCOc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccccc2C(=O)OC)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P20 compound treatment 892605.0 162000.0 0.34 732222.0 -12500.0 -0.03 0.2228 0.6464 1985618 ChemDiv2_004222 Cc1n(Cc2ccccc2)c(C)c3c(C)nnc(C)c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P21 compound treatment 809467.0 78900.0 0.17 737908.0 -6810.0 -0.02 0.1073 0.639 1263507 ChemDiv2_004223 Cc1cccc(c1)N2C(=O)C3ON(C(C3C2=O)c4ccco4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P22 compound treatment 490445.0 -240000.0 -0.51 632331.0 -112000.0 -0.26 -0.5406 -0.9492 1985619 ChemDiv2_004224 CSc1nnc-2c(OC(N(C(=O)c3ccccc3)c4ccccc42)c5ccco5)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P23 mock treatment 455814.0 -275000.0 -0.58 511373.0 -233000.0 -0.53 -0.787 -0.9989 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1380 P24 mock treatment 429216.0 -301000.0 -0.64 431301.0 -313000.0 -0.71 -0.9556 -0.9985 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A01 compound treatment 392905.0 -409000.0 -0.87 404703.0 -343000.0 -0.78 -1.164 -0.9986 1985830 ChemDiv2_004577 CC(=O)NCc1cc(ccc1C)c2nn(C)c(=O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A02 compound treatment 330503.0 -471000.0 -1.0 422174.0 -326000.0 -0.74 -1.2295 -0.9891 1985831 ChemDiv2_004578 CCNc1nc(OC)nc(n1)N2CCC(Cc3ccccc3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A03 compound treatment 460940.0 -341000.0 -0.72 425191.0 -322000.0 -0.73 -1.0291 -1.0 1985832 ChemDiv2_004579 CCOC(=O)c1ccccc1NC(=O)CN2C(=O)c3cccc4cccc2c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A04 compound treatment 511069.0 -291000.0 -0.62 507964.0 -240000.0 -0.55 -0.8209 -0.9981 1985833 ChemDiv2_004580 CCOC(=O)c1cc(CC)sc1NC(=O)Cn2c(=O)oc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A05 compound treatment 433809.0 -368000.0 -0.78 713241.0 -34400.0 -0.08 -0.6067 -0.7742 1985834 ChemDiv2_004581 COC(=O)C1CCN(CC1)C(=O)c2sc3ccccc3c2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A06 compound treatment 426070.0 -376000.0 -0.8 568496.0 -179000.0 -0.41 -0.851 -0.9516 1985835 ChemDiv2_004582 OCCN(CCO)S(=O)(=O)c1cccc2cccnc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A07 compound treatment 500988.0 -301000.0 -0.64 655288.0 -92400.0 -0.21 -0.5991 -0.8929 1257855 ChemDiv2_004583 CCc1ccc(cc1)c2cc(C(=O)Nc3ccc(cc3)S(=O)(=O)NC(=O)C)c4ccccc4n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A08 compound treatment 500068.0 -302000.0 -0.64 684720.0 -63000.0 -0.14 -0.5532 -0.8446 1337005 ChemDiv2_004584 CCOc1nsnc1N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A09 compound treatment 539915.0 -262000.0 -0.55 980041.0 232000.0 0.53 -0.0187 -0.0244 1730937 ChemDiv2_004585 CC(C)(C)C1CCc2c(C(=O)N)c(NC(=O)CCC(=O)O)sc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A10 compound treatment 392094.0 -409000.0 -0.87 689016.0 -58700.0 -0.13 -0.7082 -0.8063 1985836 ChemDiv2_004586 COc1cccc(c1)[C@@H]2Nc3ccc(cc3[C@@H]4C=CC[C@@H]42)S(=O)(=O)Nc5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A11 compound treatment 521462.0 -280000.0 -0.59 879478.0 132000.0 0.3 -0.208 -0.3128 1985837 ChemDiv2_004587 CN(C)C(=O)c1sc(NC(=O)C2CC2c3ccc(cc3)C(C)(C)C)nc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A12 compound treatment 521125.0 -280000.0 -0.59 463810.0 -284000.0 -0.65 -0.8768 -0.9992 1985838 ChemDiv2_004588 Nc1nc(CSc2ncccn2)nc(Nc3ccccc3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A13 compound treatment 602641.0 -199000.0 -0.42 543399.0 -204000.0 -0.46 -0.6266 -0.9988 1689276 ChemDiv2_004589 COc1cccc2cc(C(=O)Nc3sc(C)c(c3C(=O)N)c4ccccc4)c(=O)oc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A14 compound treatment 721750.0 -79800.0 -0.17 721500.0 -26200.0 -0.06 -0.1618 -0.9017 1985839 ChemDiv2_004590 CC1CCc2c(C1)sc3nnn(CC=C)c(=O)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A15 compound treatment 619613.0 -182000.0 -0.39 834998.0 87300.0 0.2 -0.1324 -0.3052 1985840 ChemDiv2_004591 Cn1c(=O)n(C)c2cn(c(c3ccccc3)c2c1=O)C(CO)(CO)CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A16 compound treatment 670516.0 -131000.0 -0.28 776964.0 29300.0 0.07 -0.1494 -0.5229 1985841 ChemDiv2_004592 CC1(C)CC(=O)C=C(C1)NCCN2CCN(CC2)C(=O)Cc3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A17 compound treatment 599552.0 -202000.0 -0.43 853935.0 106000.0 0.24 -0.132 -0.2685 1985842 ChemDiv2_004593 CC(C)n1c(CCC(=O)O)ccc1c2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A18 compound treatment 598467.0 -203000.0 -0.43 958751.0 211000.0 0.48 0.0348 0.054 1985843 ChemDiv2_004594 CCCCN(C)S(=O)(=O)c1cc(ccc1C)c2nn(C)c(=O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A19 compound treatment 701160.0 -100000.0 -0.21 829588.0 81900.0 0.19 -0.0189 -0.0667 1985844 ChemDiv2_004595 CC(C)NS(=O)(=O)c1ccc(OCC(=O)N2CCN(Cc3ccccc3)CC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A20 compound treatment 624862.0 -177000.0 -0.37 520767.0 -227000.0 -0.52 -0.6297 -0.9876 1985845 ChemDiv2_004596 COc1ccc(cc1)C(=O)n2c(nc3ccccc23)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A21 compound treatment 562036.0 -240000.0 -0.51 788147.0 40500.0 0.09 -0.294 -0.5698 1985846 ChemDiv2_004597 CC(C)c1cc(C(=O)O)c2cc(Br)ccc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A22 compound treatment 490126.0 -311000.0 -0.66 524825.0 -223000.0 -0.51 -0.8252 -0.9915 1985847 ChemDiv2_004598 CCn1nccc1C(=O)Nc2nccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A23 mock treatment 492445.0 -309000.0 -0.66 426930.0 -321000.0 -0.73 -0.9791 -0.9986 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 A24 mock treatment 445676.0 -356000.0 -0.75 419123.0 -329000.0 -0.75 -1.0617 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B01 compound treatment 465756.0 -336000.0 -0.71 406889.0 -341000.0 -0.77 -1.0513 -0.9991 1465260 ChemDiv2_004599 O=C(N1CCN(CC1)C(=O)c2ccc(COc3ccc4CCCc4c3)o2)c5ccco5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B02 compound treatment 825644.0 24100.0 0.05 610540.0 -137000.0 -0.31 -0.1844 -0.5837 1985848 ChemDiv2_004600 O=c1[nH]c2ccc(cc2[nH]1)S(=O)(=O)N3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B03 compound treatment 884124.0 82500.0 0.17 752569.0 4880.0 0.01 0.1316 0.7504 1165564 ChemDiv2_004601 COc1ccc(cc1)N2CC(CC2=O)C(=O)NC3CC(C)(C)NC(C)(C)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B04 compound treatment 880975.0 79400.0 0.17 998765.0 251000.0 0.57 0.5227 0.8782 1985849 ChemDiv2_004602 CN(C1CCCCC1)C(=O)c2ccc(cc2)c3nn(C)c(=O)c4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B05 compound treatment 910235.0 109000.0 0.23 856627.0 109000.0 0.25 0.338 0.9993 1985850 ChemDiv2_004603 CC(C)CCn1cnc2n(C)c(=O)n(C)c(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B06 compound treatment 1140040.0 338000.0 0.72 1006767.0 259000.0 0.59 0.9239 0.9952 1985851 ChemDiv2_004604 COc1nc(NCC(C)C)nc(Oc2ccc(=O)n(n2)c3ccccc3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B07 compound treatment 999438.0 198000.0 0.42 782649.0 35000.0 0.08 0.3528 0.8264 1985852 ChemDiv2_004605 COC(=O)C1C2OC3(CN(C(C)C)C(=O)C13)C=C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B08 compound treatment 940896.0 139000.0 0.3 879799.0 132000.0 0.3 0.4212 1.0 1985853 ChemDiv2_004606 CC1CC(C)CN(Cc2nc(N)nc(Nc3ccccc3)n2)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B09 compound treatment 1063958.0 262000.0 0.56 1036853.0 289000.0 0.66 0.8582 0.9965 1985854 ChemDiv2_004607 Cc1cccc(C)c1N(CC(O)Cn2c3ccccc3c4ccccc24)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B10 compound treatment 1015522.0 214000.0 0.45 1147895.0 400000.0 0.91 0.9641 0.9483 1985855 ChemDiv2_004608 Cc1nnc(SCc2cc(=O)n3ncnc3[nH]2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B11 compound treatment 1027866.0 226000.0 0.48 985422.0 238000.0 0.54 0.7214 0.9982 1985856 ChemDiv2_004609 CCOc1cc(ccc1OCc2cccc(F)c2)C3NC(CS3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B12 compound treatment 987698.0 186000.0 0.39 1121482.0 374000.0 0.85 0.8799 0.9391 1985857 ChemDiv2_004610 CCCCC(=O)N1CCN(CC1)c2cc(C)c(cc2F)C(=O)CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B13 compound treatment 1085858.0 284000.0 0.6 1073183.0 325000.0 0.74 0.9494 0.9948 1985858 ChemDiv2_004611 CCC(Oc1ccccc1)c2nc(no2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B14 compound treatment 1003626.0 202000.0 0.43 1098895.0 351000.0 0.8 0.8675 0.9574 1985859 ChemDiv2_004612 Cc1cc(C)cc(CC(CC(=O)Nc2nccs2)C(=O)Nc3nccs3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B15 compound treatment 1076448.0 275000.0 0.58 986135.0 238000.0 0.54 0.7954 0.9993 1985860 ChemDiv2_004613 CN(C)c1ccc(CNc2nc3ccccc3n2CC=C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B16 compound treatment 1007735.0 206000.0 0.44 981483.0 234000.0 0.53 0.6849 0.9953 1985861 ChemDiv2_004614 COC(=O)CCC(=O)c1oc2ccc(Br)cc2c1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B17 compound treatment 996826.0 195000.0 0.41 938335.0 191000.0 0.43 0.5992 0.9997 1985862 ChemDiv2_004615 COc1ccc(cc1OC)S(=O)(=O)N2Cc3ccccc3CC2C(=O)N4CCCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B18 compound treatment 968335.0 167000.0 0.35 942010.0 194000.0 0.44 0.5624 0.9939 1985863 ChemDiv2_004616 Clc1ccc(cc1)C2C=C(Nc3nc(nn23)C(=O)N4CCOCC4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B19 compound treatment 1138506.0 337000.0 0.71 1080822.0 333000.0 0.76 1.0406 0.9996 1985864 ChemDiv2_004617 CC1CC(C)CN(C1)c2oc(nc2C#N)c3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B20 compound treatment 1050940.0 249000.0 0.53 928306.0 181000.0 0.41 0.6642 0.9922 1985865 ChemDiv2_004618 Nc1nc2ccccc2n1S(=O)(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B21 compound treatment 1045171.0 244000.0 0.52 1084862.0 337000.0 0.77 0.9072 0.9815 1985866 ChemDiv2_004619 CN(Cc1ccccc1)C(=O)CN2C(=O)c3cccc4cccc2c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B22 compound treatment 970837.0 169000.0 0.36 999248.0 252000.0 0.57 0.6581 0.9748 1985867 ChemDiv2_004620 Cc1ccc(cc1)S(=O)(=O)N(CC(O)Cn2c3ccccc3c4ccccc24)CC(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B23 mock treatment 753046.0 -48500.0 -0.1 835346.0 87700.0 0.2 0.0682 0.3039 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 B24 mock treatment 475766.0 -326000.0 -0.69 559694.0 -188000.0 -0.43 -0.7906 -0.9734 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C01 compound treatment 454461.0 -347000.0 -0.74 556886.0 -191000.0 -0.43 -0.8271 -0.9682 1985868 ChemDiv2_004621 CCC(=O)NCc1cc(ccc1C)c2nn(C)c(=O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C02 compound treatment 987795.0 186000.0 0.39 1023240.0 276000.0 0.63 0.7221 0.9752 1985869 ChemDiv2_004622 CCNc1nc(nc(n1)N2CCC(Cc3ccccc3)CC2)N4CCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C03 compound treatment 849398.0 47800.0 0.1 904860.0 157000.0 0.36 0.3244 0.8732 1985870 ChemDiv2_004623 CN(C)C(=O)c1ccc(cc1)C2SCC(=O)N2CCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C04 compound treatment 1089852.0 288000.0 0.61 1138979.0 391000.0 0.89 1.0612 0.9832 1985871 ChemDiv2_004624 Cc1nnc(NC(=O)Cn2c(=O)sc3ccccc23)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C05 compound treatment 1039955.0 238000.0 0.51 1088536.0 341000.0 0.77 0.9053 0.9785 1985872 ChemDiv2_004625 Cc1cccc(N2CCN(CC2)C(=O)C3C(C4OC3C=C4)C(=O)O)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C06 compound treatment 1065832.0 264000.0 0.56 1237839.0 490000.0 1.11 1.1841 0.9494 1985873 ChemDiv2_004626 Cc1ccc(Cl)cc1NC(=O)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C07 compound treatment 1094276.0 293000.0 0.62 1202610.0 455000.0 1.03 1.1701 0.9701 1369804 ChemDiv2_004627 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2cnc3ccccc3n2)c4ccc5OCOc5c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C08 compound treatment 1180863.0 379000.0 0.8 1128270.0 381000.0 0.87 1.1804 0.9993 1731466 ChemDiv2_004628 C(Oc1nsnc1N2CCOCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C09 compound treatment 1117436.0 316000.0 0.67 1160749.0 413000.0 0.94 1.1375 0.9863 1729202 ChemDiv2_004629 O=C(N1CCc2ccccc2C1)c3cc4ccccc4c(=O)o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C10 compound treatment 1261577.0 460000.0 0.98 1110335.0 363000.0 0.82 1.2726 0.9965 1985874 ChemDiv2_004630 Brc1ccc(cc1)N2OC3C(C2c4cccnc4)C(=O)N(C3=O)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C11 compound treatment 1081755.0 280000.0 0.59 1174648.0 427000.0 0.97 1.1064 0.9722 1985875 ChemDiv2_004631 CCOc1ccc(cc1)C(=O)Nc2cnn(Cc3ccc(F)cc3)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C12 compound treatment 1359686.0 558000.0 1.18 1309831.0 562000.0 1.28 1.7403 0.9993 1985876 ChemDiv2_004632 Cc1cc2nc(SCCOC(=O)CN3C(=O)c4ccccc4C3=O)nc(C)c2cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C13 compound treatment 1351921.0 550000.0 1.17 1236458.0 489000.0 1.11 1.6107 0.9997 1985877 ChemDiv2_004633 COC(=O)Nc1cc(C)nc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C14 compound treatment 1182277.0 381000.0 0.81 1012121.0 264000.0 0.6 0.9958 0.9895 1985878 ChemDiv2_004634 CCCn1nnc2sc3CC(C)CCc3c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C15 compound treatment 1131019.0 329000.0 0.7 1003753.0 256000.0 0.58 0.9055 0.9959 1985879 ChemDiv2_004635 COc1ccc(CCn2cc3n(C)c(=O)n(C)c(=O)c3c2c4ccccc4)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C16 compound treatment 1069851.0 268000.0 0.57 1157331.0 410000.0 0.93 1.0607 0.972 1985880 ChemDiv2_004636 CCn1c(SCc2nc(O)c3ccccc3n2)nc4ccccc4c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C17 compound treatment 1218833.0 417000.0 0.88 1121109.0 373000.0 0.85 1.2258 0.9998 1985881 ChemDiv2_004637 OC(=O)CCc1ccc(c2cccs2)n1Cc3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C18 compound treatment 1010703.0 209000.0 0.44 1221582.0 474000.0 1.08 1.0753 0.923 1985882 ChemDiv2_004638 Cc1ccc(cc1S(=O)(=O)N2CCN(Cc3ccccc3)CC2)c4n[nH]c(=O)c5ccccc45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C19 compound treatment 1262143.0 461000.0 0.98 1158230.0 411000.0 0.93 1.3504 0.9997 1985883 ChemDiv2_004639 COc1ccc(Nc2nc(nc3ccccc23)N4CCCC4)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C20 compound treatment 1209569.0 408000.0 0.86 886781.0 139000.0 0.32 0.8352 0.9069 1985884 ChemDiv2_004640 Nc1nc(SCc2ccccc2Cl)n[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C21 compound treatment 1174722.0 373000.0 0.79 948367.0 201000.0 0.46 0.882 0.9658 1985885 ChemDiv2_004641 CCNc1nc(Cl)nc(Oc2ccc(=O)n(n2)c3ccccc3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C22 compound treatment 1096809.0 295000.0 0.63 905522.0 158000.0 0.36 0.6963 0.9651 1985886 ChemDiv2_004642 COC(=O)c1ccccc1NC(=O)CSc2ccccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C23 mock treatment 932233.0 131000.0 0.28 836252.0 88600.0 0.2 0.3382 0.9877 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 C24 mock treatment 576917.0 -225000.0 -0.48 400105.0 -348000.0 -0.79 -0.8956 -0.9706 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D01 compound treatment 414145.0 -387000.0 -0.82 569506.0 -178000.0 -0.41 -0.8672 -0.947 1440675 ChemDiv2_004643 Brc1cnn(Cc2ccc(cc2)C(=O)N3CCN(CC3)C(=O)c4ccco4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D02 compound treatment 815828.0 14200.0 0.03 900931.0 153000.0 0.35 0.2677 0.7655 1007736 ChemDiv2_004644 Cn1c(OCc2ccccc2)nc3n(C)c(=O)n(C)c(=O)c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D03 compound treatment 957971.0 156000.0 0.33 983891.0 236000.0 0.54 0.6142 0.9731 1356215 ChemDiv2_004645 S=c1sc2c(ncnc2n1c3ccccc3)N4CCOCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D04 compound treatment 1066763.0 265000.0 0.56 824082.0 76400.0 0.17 0.5203 0.8843 1985887 ChemDiv2_004646 Cn1nc(c2ccc(cc2)C(=O)NCCN3CCOCC3)c4ccccc4c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D05 compound treatment 1236177.0 435000.0 0.92 1197878.0 450000.0 1.02 1.3752 0.9986 1985888 ChemDiv2_004647 COC(=O)c1ccc(NC(=O)Cn2c(nc3ccccc23)c4cncs4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D06 compound treatment 1505383.0 704000.0 1.49 1217265.0 470000.0 1.07 1.8099 0.9865 1363845 ChemDiv2_004648 OC(=O)c1ccccc1C(=O)n2cnc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D07 compound treatment 1239756.0 438000.0 0.93 1243060.0 495000.0 1.13 1.4532 0.9954 1985889 ChemDiv2_004649 CCOC(=O)C1C2OC3(CN(C(=O)C13)c4ccc(Cl)c(F)c4)C=C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D08 compound treatment 1206783.0 405000.0 0.86 981279.0 234000.0 0.53 0.9829 0.9733 1985890 ChemDiv2_004650 Cc1ccc(Nc2nc(N)nc(CSc3nnc(o3)c4ccncc4)n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D09 compound treatment 1214305.0 413000.0 0.87 1342499.0 595000.0 1.35 1.5749 0.9778 1985891 ChemDiv2_004651 COc1cc(cc(OC)c1OC)c2nc3n(ncc3c(=O)[nH]2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D10 compound treatment 1147309.0 346000.0 0.73 1050240.0 303000.0 0.69 1.0047 0.9995 1985892 ChemDiv2_004652 CCN1C(=O)c2ccc(cc2C1=O)c3nc4ccccc4c(=O)o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D11 compound treatment 1366139.0 565000.0 1.2 1240016.0 492000.0 1.12 1.6378 0.9994 1985893 ChemDiv2_004653 CCOC(=O)COc1ccc(cc1OC)C2NC(CS2)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D12 compound treatment 1558778.0 757000.0 1.61 1272470.0 525000.0 1.19 1.9787 0.9893 1985894 ChemDiv2_004654 Cc1ccc(OCc2nc(C#N)c(NCC=C)o2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D13 compound treatment 1699677.0 898000.0 1.9 1375011.0 627000.0 1.43 2.3548 0.9899 1985895 ChemDiv2_004655 Cc1nnc(SCC(=O)c2c(C)[nH]c3ccccc23)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D14 compound treatment 1460635.0 659000.0 1.4 1269228.0 522000.0 1.19 1.8264 0.9967 1985896 ChemDiv2_004656 CC1(C)CC(CCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3)C(=O)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D15 compound treatment 1141038.0 339000.0 0.72 1265170.0 517000.0 1.18 1.3408 0.9722 1985897 ChemDiv2_004657 Cc1ccc(cc1)C2N(C(=O)c3oc4ccccc4c(=O)c23)c5nccs5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D16 compound treatment 1323528.0 522000.0 1.11 964100.0 216000.0 0.49 1.1303 0.9334 1985898 ChemDiv2_004658 CCOC(=O)c1c(CN2CCN(CC#N)CC2)n(c3ccccc3)c4ccc(O)cc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D17 compound treatment 1218424.0 417000.0 0.88 1305998.0 558000.0 1.27 1.5224 0.9843 1985899 ChemDiv2_004659 Cc1noc(C)c1CSc2nc3ccccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D18 compound treatment 1423509.0 622000.0 1.32 1211784.0 464000.0 1.06 1.6784 0.9939 1985900 ChemDiv2_004660 CCS(=O)(=O)n1nc(nc1N)C(=O)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D19 compound treatment 1148086.0 347000.0 0.73 1153003.0 405000.0 0.92 1.171 0.9937 1985901 ChemDiv2_004661 CCOc1ccc(cc1)c2nc(C#N)c(o2)N3CCN(CC)CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D20 compound treatment 1055403.0 254000.0 0.54 1016820.0 269000.0 0.61 0.8132 0.9979 1985902 ChemDiv2_004662 CCCCN1C(=O)C(O)(CC(=O)c2ccco2)c3cc(Br)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D21 compound treatment 1092450.0 291000.0 0.62 1064700.0 317000.0 0.72 0.9457 0.997 1985903 ChemDiv2_004663 CCOc1ccccc1NC(=O)CN2C(=O)c3cccc4cccc2c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D22 compound treatment 1009028.0 207000.0 0.44 886537.0 139000.0 0.32 0.5342 0.9868 1985904 ChemDiv2_004664 CC(=O)N1CCC(CC1)C(=O)Nc2nc(ns2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D23 mock treatment 946103.0 145000.0 0.31 737523.0 -10200.0 -0.02 0.2003 0.6519 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 D24 mock treatment 598199.0 -203000.0 -0.43 367581.0 -380000.0 -0.86 -0.916 -0.9484 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E01 compound treatment 567243.0 -234000.0 -0.5 644802.0 -103000.0 -0.23 -0.5167 -0.941 1985905 ChemDiv2_004665 CCc1ccc(OCc2nc(no2)c3ccncc3)c(Br)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E02 compound treatment 907302.0 106000.0 0.22 1043643.0 296000.0 0.67 0.6343 0.8943 1985906 ChemDiv2_004666 Cc1cc(NC(=O)COC(=O)Cn2ccc(=O)[nH]c2=O)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E03 compound treatment 977768.0 176000.0 0.37 1078189.0 330000.0 0.75 0.7954 0.9479 1985907 ChemDiv2_004667 CCN(CC)c1ncnc2c1sc3nc(C)cc(C)c32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E04 compound treatment 1187774.0 386000.0 0.82 1123290.0 376000.0 0.85 1.1827 0.9998 1985908 ChemDiv2_004668 OC(=O)c1ccc(COc2ccc(cc2)C3C4=C(CCCC4=O)OC5=C3C(=O)CCC5)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E05 compound treatment 1178401.0 377000.0 0.8 1140857.0 393000.0 0.89 1.1969 0.9984 1985909 ChemDiv2_004669 NS(=O)(=O)c1ccc(NC(=O)c2cc(nc3ccccc23)c4ccc5OCOc5c4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E06 compound treatment 1342286.0 541000.0 1.15 1123962.0 376000.0 0.86 1.4154 0.9896 1985910 ChemDiv2_004670 O=C(N1CCCCC1)c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E07 compound treatment 1082958.0 281000.0 0.6 1202253.0 455000.0 1.03 1.1526 0.9659 1307325 ChemDiv2_004671 Cc1cc(NC(=O)CCCC(=O)O)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E08 compound treatment 1303245.0 502000.0 1.06 1129358.0 382000.0 0.87 1.3656 0.9949 1985911 ChemDiv2_004672 CCCN1C(=O)SC(CC(=O)Nc2ccccc2)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E09 compound treatment 1185900.0 384000.0 0.81 1116694.0 369000.0 0.84 1.1693 0.9999 1880677 ChemDiv2_004673 COc1cc(cc(OC)c1OC)c2cc(C(=O)O)c3cc(Br)ccc3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E10 compound treatment 1576815.0 775000.0 1.64 1213343.0 466000.0 1.06 1.9107 0.9774 1985912 ChemDiv2_004674 CCN(C)CCc1c[nH]c2ccc(OC)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E11 compound treatment 1388767.0 587000.0 1.24 1201052.0 453000.0 1.03 1.6091 0.9956 1985913 ChemDiv2_004675 Fc1cccc(Cl)c1Cn2ccc(NC(=O)c3cc4ccccc4oc3=O)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E12 compound treatment 1390009.0 588000.0 1.25 1293598.0 546000.0 1.24 1.7597 1.0 1985914 ChemDiv2_004676 CN(C(=O)C(OC(=O)C)c1ccccc1)c2nnc(s2)c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E13 compound treatment 1486869.0 685000.0 1.45 1267010.0 519000.0 1.18 1.8622 0.9947 1985915 ChemDiv2_004677 O=C(Nc1nnc(s1)c2ccncc2)C3c4ccccc4Oc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E14 compound treatment 1256540.0 455000.0 0.96 1249823.0 502000.0 1.14 1.4893 0.9965 1985916 ChemDiv2_004678 O=C(Cn1nnc2sc3CCCCc3c2c1=O)OCc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E15 compound treatment 1287392.0 486000.0 1.03 1308663.0 561000.0 1.28 1.6301 0.9944 1985917 ChemDiv2_004679 Clc1ccc(cc1)c2noc(COc3ccc4OCOc4c3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E16 compound treatment 1142574.0 341000.0 0.72 1209942.0 462000.0 1.05 1.2543 0.9833 1985918 ChemDiv2_004680 Cn1c(=O)n(C)c2ncn(CC(O)CN3C(=O)c4ccccc4S3(=O)=O)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E17 compound treatment 1124300.0 323000.0 0.68 1283620.0 536000.0 1.22 1.3454 0.9628 1985919 ChemDiv2_004681 COc1ccc(cc1)c2ccc(CCC(=O)O)n2c3ccc(cc3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E18 compound treatment 1046607.0 245000.0 0.52 1085598.0 338000.0 0.77 0.9105 0.9818 1985920 ChemDiv2_004682 C(Oc1nnc(c2ccccc2)c3ccccc13)c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E19 compound treatment 997916.0 196000.0 0.42 1155077.0 407000.0 0.93 0.9492 0.9348 1517029 ChemDiv2_004683 CC(C)NCc1c(O)c(Br)cc2oc3CCCCc3c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E20 compound treatment 1077542.0 276000.0 0.59 1171485.0 424000.0 0.96 1.095 0.9714 1985921 ChemDiv2_004684 Cc1ccc(CSc2n[nH]c(N)n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E21 compound treatment 1082314.0 281000.0 0.6 960627.0 213000.0 0.48 0.7632 0.9948 1985922 ChemDiv2_004685 CC(C)(C)Nc1nc(Cl)nc(Oc2ccc(=O)n(n2)c3ccccc3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E22 compound treatment 1036084.0 235000.0 0.5 946848.0 199000.0 0.45 0.6717 0.9989 1210337 ChemDiv2_004686 Cc1ccc2nc(NC(=O)c3ccc(Cn4cc(Cl)cn4)o3)sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E23 mock treatment 903575.0 102000.0 0.22 886127.0 138000.0 0.31 0.3755 0.9832 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 E24 mock treatment 631910.0 -170000.0 -0.36 696104.0 -51600.0 -0.12 -0.3373 -0.8915 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F01 compound treatment 734506.0 -67100.0 -0.14 683128.0 -64600.0 -0.15 -0.2043 -0.9999 1985923 ChemDiv2_004687 CCn1nccc1C(=O)Nc2ccc(C)c(C)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F02 compound treatment 1017131.0 216000.0 0.46 1239652.0 492000.0 1.12 1.114 0.922 1985924 ChemDiv2_004688 Cn1nc(c2ccc(OCC(=O)N)cc2)c3ccccc3c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F03 compound treatment 1142405.0 341000.0 0.72 1213384.0 466000.0 1.06 1.2596 0.9826 1985925 ChemDiv2_004689 Cc1c(nc(N)c(C#N)c1c2ccco2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F04 compound treatment 1412113.0 611000.0 1.29 1398191.0 651000.0 1.48 1.961 0.9978 1985926 ChemDiv2_004690 CN(C(=O)c1ccc(cc1)c2nn(C)c(=O)c3ccccc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F05 compound treatment 1442608.0 641000.0 1.36 1428799.0 681000.0 1.55 2.0559 0.9979 1985927 ChemDiv2_004691 CSc1nc2sc3COC(C)(C)Cc3c2c4nnc(SCC(=O)Nc5ccccc5)n14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F06 compound treatment 1400862.0 599000.0 1.27 1456880.0 709000.0 1.61 2.0385 0.993 1985928 ChemDiv2_004692 COc1ccc(cc1)C2C(=C(Nc3ncnn23)C(C)(C)C)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F07 compound treatment 1281545.0 480000.0 1.02 1405985.0 658000.0 1.5 1.7778 0.9823 1985929 ChemDiv2_004693 CCCn1c(OC)nc2n(C)c(=O)n(C)c(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F08 compound treatment 1286309.0 485000.0 1.03 1435310.0 688000.0 1.56 1.8321 0.9793 1985930 ChemDiv2_004694 Cc1cc(C)nc(n1)N(CC(=O)N2c3ccccc3CCc4ccccc24)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F09 compound treatment 1554773.0 753000.0 1.6 1383422.0 636000.0 1.45 2.1511 0.9988 1985931 ChemDiv2_004695 COC(=O)C(Cc1c[nH]c2ccccc12)NC3OC(=O)c4c3ccc(OC)c4OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F10 compound treatment 1632787.0 831000.0 1.76 1420256.0 673000.0 1.53 2.3273 0.9975 1985932 ChemDiv2_004696 CN(C)S(=O)(=O)N1CCN(CC1)C(=O)c2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F11 compound treatment 1674888.0 873000.0 1.85 1367343.0 620000.0 1.41 2.3053 0.9909 1985933 ChemDiv2_004697 c1ccc(cc1)c2nc3[nH]c4ccccc4n3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F12 compound treatment 1803501.0 1000000.0 2.12 1824900.0 1080000.0 2.45 3.2337 0.9975 1985934 ChemDiv2_004698 CN(Cc1ccccc1)c2oc(COc3ccccc3F)nc2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F13 compound treatment 1353819.0 552000.0 1.17 2016100.0 1270000.0 2.88 2.867 0.9212 1985935 ChemDiv2_004699 Cc1[nH]c2ccccc2c1C(=O)CSc3nnc(N)s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F14 compound treatment 1211939.0 410000.0 0.87 1448349.0 701000.0 1.59 1.7416 0.9595 1985936 ChemDiv2_004700 CCC(C)Nc1nc(OC)nc(Oc2ccc(O)nn2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F15 compound treatment 1345507.0 544000.0 1.15 1312609.0 565000.0 1.28 1.7236 0.9986 1985937 ChemDiv2_004701 O=C1N(C(c2c1oc3ccccc3c2=O)c4ccncc4)c5nccs5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F16 compound treatment 1192400.0 391000.0 0.83 1254246.0 507000.0 1.15 1.4002 0.9869 1985938 ChemDiv2_004702 Nc1c(oc2ccc(Br)cc12)C(=O)CCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F17 compound treatment 1343714.0 542000.0 1.15 1154966.0 407000.0 0.93 1.4674 0.9943 1985939 ChemDiv2_004703 Cn1c(SCCNS(=O)(=O)c2ccccc2)nc3n(C)c(=O)n(C)c(=O)c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F18 compound treatment 1687203.0 886000.0 1.88 1268830.0 521000.0 1.18 2.1654 0.9754 1985940 ChemDiv2_004704 Nc1nc(nn1S(=O)(=O)c2ccccc2)C(=O)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F19 compound treatment 1492020.0 690000.0 1.46 1171902.0 424000.0 0.96 1.717 0.9795 1985941 ChemDiv2_004705 Cc1ccc(cc1)c2nc(C#N)c(NCCCN3CCOCC3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F20 compound treatment 1319081.0 518000.0 1.1 1175529.0 428000.0 0.97 1.4636 0.9982 1985942 ChemDiv2_004706 COc1ccc(cc1)C2C(=C(N)Oc3c2ccc(=O)c4c(C)oc(C)c34)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F21 compound treatment 1367815.0 566000.0 1.2 947141.0 199000.0 0.45 1.1695 0.9114 1985943 ChemDiv2_004707 CCc1ccc2NC(C3CC=CC3c2c1)c4ccc(cc4)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F22 compound treatment 1196243.0 395000.0 0.84 1025389.0 278000.0 0.63 1.0381 0.9904 1985944 ChemDiv2_004708 COCC(=O)Nc1nc(ns1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F23 mock treatment 1196321.0 395000.0 0.84 1174422.0 427000.0 0.97 1.2778 0.9973 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 F24 mock treatment 664541.0 -137000.0 -0.29 571611.0 -176000.0 -0.4 -0.4885 -0.9876 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G01 compound treatment 870131.0 68600.0 0.15 690358.0 -57300.0 -0.13 0.0106 0.0543 1985945 ChemDiv2_004709 CCc1nn2c(=O)cc(nc2s1)N3CCN(CC3)c4cc(C)nc5ccccc45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G02 compound treatment 1234419.0 433000.0 0.92 860342.0 113000.0 0.26 0.8299 0.8712 1985946 ChemDiv2_004710 CCn1cc(Br)c(n1)C(=O)NCc2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G03 compound treatment 1105395.0 304000.0 0.64 928566.0 181000.0 0.41 0.7462 0.9765 1985947 ChemDiv2_004711 OC(=O)CCC(=O)NCC1OCCc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G04 compound treatment 1131495.0 330000.0 0.7 1041480.0 294000.0 0.67 0.9669 0.9997 1985948 ChemDiv2_004712 OC(=O)COc1ccc(cc1)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G05 compound treatment 1497276.0 696000.0 1.47 1081825.0 334000.0 0.76 1.58 0.9524 1985949 ChemDiv2_004713 COC(=O)c1sc(NC(=O)C2c3ccccc3Oc4ccccc24)nc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G06 compound treatment 1774616.0 973000.0 2.06 1175476.0 428000.0 0.97 2.1463 0.9411 1985950 ChemDiv2_004714 Cc1ccccc1NC(=O)C2Cc3ccccc3C(=O)O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G07 compound treatment 1470515.0 669000.0 1.42 1112407.0 365000.0 0.83 1.5891 0.9673 1399422 ChemDiv2_004715 CCN1CCN(CC1)C(=O)c2ccc(COc3ccc(Cl)cc3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G08 compound treatment 1736055.0 934000.0 1.98 1067071.0 319000.0 0.73 1.9143 0.9073 1292618 ChemDiv2_004716 CCOc1ccc(NC(=O)CC2SC(=O)N(C2=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G09 compound treatment 1746921.0 945000.0 2.0 1090935.0 343000.0 0.78 1.9689 0.9155 1880696 ChemDiv2_004717 OC(=O)C1C(C2CC1C=C2)C(=O)N3CCN(C/C=C/c4ccccc4)CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G10 compound treatment 1858659.0 1060000.0 2.24 1298743.0 551000.0 1.25 2.4705 0.9623 1505341 ChemDiv2_004718 CCOC(=O)c1cc2ccccc2n1CCN(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G11 compound treatment 1761720.0 960000.0 2.04 1646599.0 899000.0 2.04 2.8844 1.0 1985951 ChemDiv2_004719 Cc1ccc(o1)C(=O)N2CCCN(CC2)C(=O)c3ccc(C)o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G12 compound treatment 1004810.0 203000.0 0.43 1152287.0 405000.0 0.92 0.9551 0.9403 1985952 ChemDiv2_004720 COc1ccc(cc1)C(=O)N(CC=C)c2nnc(s2)c3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G13 compound treatment 1380333.0 579000.0 1.23 1361561.0 614000.0 1.4 1.8545 0.9979 1882167 ChemDiv2_004721 OC(=O)C1C(C2CCC1O2)C(=O)N3CCN(CC3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G14 compound treatment 1381293.0 580000.0 1.23 1106993.0 359000.0 0.82 1.4466 0.9803 1985953 ChemDiv2_004722 Fc1ccccc1Cn2nnc3sc4CCCCc4c3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G15 compound treatment 1622628.0 821000.0 1.74 1626781.0 879000.0 2.0 2.644 0.9976 1500480 ChemDiv2_004723 CCN1C(C(C)C(=O)C(C)C1c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G16 compound treatment 1823785.0 1020000.0 2.17 1541134.0 793000.0 1.8 2.8079 0.9958 1595276 ChemDiv2_004724 Cc1cccc(NCC(O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G17 compound treatment 1758265.0 957000.0 2.03 1158120.0 410000.0 0.93 2.0939 0.9379 1985954 ChemDiv2_004725 OC(=O)CCc1ccc(c2cccs2)n1c3ccc(cc3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G18 compound treatment 1281574.0 480000.0 1.02 1186794.0 439000.0 1.0 1.4255 1.0 1985955 ChemDiv2_004726 Cc1ccc(cc1)c2nnc(OCCN3CCOCC3)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G19 compound treatment 1289572.0 488000.0 1.03 1029512.0 282000.0 0.64 1.1846 0.9735 1985956 ChemDiv2_004727 COc1ccccc1N2Cc3ccccc3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G20 compound treatment 1344663.0 543000.0 1.15 954594.0 207000.0 0.47 1.1467 0.922 1985957 ChemDiv2_004728 Nc1nc(n[nH]1)S(=O)(=O)Cc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G21 compound treatment 1066113.0 265000.0 0.56 794928.0 47200.0 0.11 0.4725 0.8275 1985958 ChemDiv2_004729 COC(=O)Cc1[nH]nc2OC(=C(C#N)C(C3CCCC=C3)c12)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G22 compound treatment 1137449.0 336000.0 0.71 746376.0 -1310.0 0.0 0.5014 0.7041 1717827 ChemDiv2_004730 CN1CCN(CC1)C(=O)c2ccc(Cn3cc(Cl)cn3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G23 mock treatment 918440.0 117000.0 0.25 771403.0 23700.0 0.05 0.2133 0.8413 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 G24 mock treatment 467417.0 -334000.0 -0.71 450966.0 -297000.0 -0.67 -0.9779 -0.9997 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H01 compound treatment 840085.0 38500.0 0.08 680919.0 -66800.0 -0.15 -0.0496 -0.2879 1985959 ChemDiv2_004731 CCn1ncc(Cl)c1C(=O)NC(C)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H02 compound treatment 1167887.0 366000.0 0.78 1019411.0 272000.0 0.62 0.9859 0.9936 1985960 ChemDiv2_004732 CC1CCN(CC1)C(=O)COc2ccc(cc2)c3nn(C)c(=O)c4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H03 compound treatment 1068688.0 267000.0 0.57 1125366.0 378000.0 0.86 1.0076 0.9796 1985961 ChemDiv2_004733 O=C(Nc1nccs1)C2CC(=O)OC2c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H04 compound treatment 1226266.0 425000.0 0.9 1022982.0 275000.0 0.63 1.0792 0.9842 1985962 ChemDiv2_004734 CCCC(=O)N1CCN(CC1)c2nnc(c3ccc(C)cc3)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H05 compound treatment 1732016.0 930000.0 1.97 1422491.0 675000.0 1.53 2.4796 0.9923 1985963 ChemDiv2_004735 COc1ccccc1NC(=O)CSc2nnc3c4c5CCN(C)Cc5sc4nc(SC)n23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H06 compound treatment 1784078.0 982000.0 2.08 1379655.0 632000.0 1.44 2.4888 0.9836 1985964 ChemDiv2_004736 CCSC1=NN1c2cc(C)nc(N)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H07 compound treatment 1531116.0 730000.0 1.55 1384347.0 637000.0 1.45 2.1171 0.9995 1985965 ChemDiv2_004737 COc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H08 compound treatment 1893555.0 1090000.0 2.31 1462729.0 715000.0 1.63 2.7864 0.985 1985966 ChemDiv2_004738 Cc1[nH]c2ccccc2c1C(=O)CSc3nncn3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H09 compound treatment 2146399.0 1340000.0 2.85 1336216.0 589000.0 1.34 2.9621 0.9405 1985967 ChemDiv2_004739 O=C(Cn1c(=O)oc2ccccc12)Nc3nc4CCCCc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H10 compound treatment 1932770.0 1130000.0 2.4 1505549.0 758000.0 1.72 2.9141 0.9868 1985968 ChemDiv2_004740 CN(C)S(=O)(=O)N1CCN(CC1)C(=O)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H11 compound treatment 2004592.0 1200000.0 2.55 1842200.0 1090000.0 2.49 3.5629 0.9999 1985969 ChemDiv2_004741 COC(=O)c1ccc(cc1)C(=O)Nc2ccc3[nH]c(nc3c2)c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H12 compound treatment 2152605.0 1350000.0 2.86 1254667.0 507000.0 1.15 2.8403 0.92 1985970 ChemDiv2_004742 N#Cc1nc(COc2ccccc2)oc1N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H13 compound treatment 1472294.0 671000.0 1.42 1544952.0 797000.0 1.81 2.2871 0.9928 1985971 ChemDiv2_004743 CCOC(=O)N1CCN(CC1)C(=O)C(C)(C)Oc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H14 compound treatment 1871401.0 1070000.0 2.27 1906378.0 1160000.0 2.63 3.4665 0.9972 1528125 ChemDiv2_004744 CCOC(=O)c1c(CN2CCCCC2)oc3ccc(OC)cc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H15 compound treatment 1649944.0 848000.0 1.8 1780600.0 1030000.0 2.35 2.9323 0.9913 1985972 ChemDiv2_004745 CCOC(=O)c1sc(nc1C)N2C(c3c(oc4ccccc4c3=O)C2=O)c5ccc(O)c(OCC)c5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H16 compound treatment 1844903.0 1040000.0 2.21 1195596.0 448000.0 1.02 2.2841 0.938 1985973 ChemDiv2_004746 CCOC(=O)c1c(CN(CC)CC)oc2ccc(O)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H17 compound treatment 1481452.0 680000.0 1.44 1596520.0 849000.0 1.93 2.3838 0.9897 1985974 ChemDiv2_004747 CC(C)(C)NC(=O)Cn1c(=O)oc2ccc(Cl)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H18 compound treatment 1827289.0 1030000.0 2.17 1120393.0 373000.0 0.85 2.1367 0.9156 1985975 ChemDiv2_004748 Nc1nc(NCc2ccc(F)cc2)nn1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H19 compound treatment 1779115.0 978000.0 2.07 1115288.0 368000.0 0.84 2.0563 0.9203 1464653 ChemDiv2_004749 COc1ccc(cc1)c2nc(C#N)c(o2)N3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H20 compound treatment 1435682.0 634000.0 1.34 1088699.0 341000.0 0.78 1.4988 0.9658 1985976 ChemDiv2_004750 CC1(CC2C(C(=O)OCc3ccccc3)C(=O)N1)Oc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H21 compound treatment 1267419.0 466000.0 0.99 1092574.0 345000.0 0.78 1.2528 0.9935 1985977 ChemDiv2_004751 O=C(CN1C(=O)c2cccc3cccc1c23)Nc4ccc(cc4)S(=O)(=O)Nc5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H22 compound treatment 1282470.0 481000.0 1.02 1093190.0 345000.0 0.79 1.2763 0.9917 1014053 ChemDiv2_004752 O=c1[nH]n(c2ccccc2)c(=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H23 mock treatment 1132019.0 330000.0 0.7 1187236.0 440000.0 1.0 1.202 0.9849 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 H24 mock treatment 845186.0 43600.0 0.09 822472.0 74800.0 0.17 0.1856 0.959 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I01 compound treatment 854968.0 53400.0 0.11 730023.0 -17700.0 -0.04 0.0516 0.4299 1985978 ChemDiv2_004753 CCc1nn2c(=O)cc(nc2s1)N3CCNCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I02 compound treatment 1329068.0 527000.0 1.12 1100097.0 352000.0 0.8 1.3573 0.9866 1985979 ChemDiv2_004754 Cc1nc2c3cc4COC(C)(C)Cc4nc3sc2c(=O)n1Cc5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I03 compound treatment 1246637.0 445000.0 0.94 1252054.0 504000.0 1.15 1.478 0.9953 1985980 ChemDiv2_004755 COc1cc(ccc1OC(=O)C)C2Nc3ccc4ncccc4c3C5=C2C(=O)CCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I04 compound treatment 1347508.0 546000.0 1.16 1140191.0 393000.0 0.89 1.4494 0.9917 1985981 ChemDiv2_004756 CC1(C)CC(CCO1)C(=O)Nc2nccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I05 compound treatment 1568721.0 767000.0 1.63 1242293.0 495000.0 1.12 1.9451 0.9838 1592233 ChemDiv2_004757 Cc1noc(C)c1C(=O)N2CCC(CC2)C(O)(c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I06 compound treatment 1652425.0 851000.0 1.8 1296764.0 549000.0 1.25 2.1582 0.9838 1365319 ChemDiv2_004758 OC(=O)Cn1c2ccccc2c3nc4ccccc4nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I07 compound treatment 1519159.0 718000.0 1.52 1634906.0 887000.0 2.02 2.502 0.9903 1921120 ChemDiv2_004759 O=C(Cc1ccccc1)N2CCN(C/C=C/c3ccccc3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I08 compound treatment 1764880.0 963000.0 2.04 1452091.0 704000.0 1.6 2.5764 0.9928 1985982 ChemDiv2_004760 C=CCn1c(SCC(=O)c2ccc3cc[nH]c3c2)nnc1c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I09 compound treatment 1413435.0 612000.0 1.3 1521104.0 773000.0 1.76 2.1606 0.9888 1985983 ChemDiv2_004761 OC(=O)C1C(C2CCC1O2)C(=O)Nc3cnn(Cc4ccccc4)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I10 compound treatment 1636719.0 835000.0 1.77 1747977.0 1000000.0 2.27 2.86 0.9923 1985984 ChemDiv2_004762 Cc1cc(C)nc(NC(=N)O)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I11 compound treatment 1682077.0 880000.0 1.87 1501194.0 754000.0 1.71 2.5313 0.9991 1985985 ChemDiv2_004763 Cc1ccccc1Cn2cc(NC(=O)c3cc4ccccc4oc3=O)cn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I12 compound treatment 1562537.0 761000.0 1.61 1802273.0 1050000.0 2.4 2.8361 0.9814 1985986 ChemDiv2_004764 Cc1nnc(SCC(=O)N2CCc3ccccc3C2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I13 compound treatment 1685079.0 883000.0 1.87 1941414.0 1190000.0 2.71 3.2435 0.9836 1882173 ChemDiv2_004765 COc1ccc(OC)c(c1)c2cc(C(=O)N3CCN(CC3)c4ncccn4)c5ccccc5n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I14 compound treatment 1345567.0 544000.0 1.15 1837441.0 1090000.0 2.48 2.5674 0.9395 1985987 ChemDiv2_004766 O=C(Cn1nnc2sc3CCCCc3c2c1=O)N4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I15 compound treatment 1289987.0 488000.0 1.04 1800686.0 1050000.0 2.39 2.425 0.9297 1985988 ChemDiv2_004767 CCCCn1c(CCC(=O)O)ccc1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I16 compound treatment 1184490.0 383000.0 0.81 1572793.0 825000.0 1.88 1.9005 0.9298 1985989 ChemDiv2_004768 CCNc1nc(N)nc(Sc2ccc(cc2)C(=O)OC)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I17 compound treatment 1308429.0 507000.0 1.07 1414645.0 667000.0 1.52 1.832 0.9858 1985990 ChemDiv2_004769 Cc1ccc(cc1C)N2Cc3ccccc3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I18 compound treatment 1361554.0 560000.0 1.19 1394990.0 647000.0 1.47 1.88 0.9943 1985991 ChemDiv2_004770 Nc1cc(=O)nc(SCC(=O)Nc2ccccc2)n1CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I19 compound treatment 1488208.0 687000.0 1.46 1165378.0 418000.0 0.95 1.7008 0.9786 1985992 ChemDiv2_004771 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc4CCCc4cc3C#N)cc2)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I20 compound treatment 1234602.0 433000.0 0.92 1169255.0 422000.0 0.96 1.3268 0.9998 1465078 ChemDiv2_004772 Cc1cc(C)n(CC(=O)NC2CCCCC2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I21 compound treatment 1184735.0 383000.0 0.81 1042681.0 295000.0 0.67 1.0486 0.9955 1985993 ChemDiv2_004773 CCOC(=O)CCc1c(C)nc(SCc2ccc(cc2)C(=O)O)c(C#N)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I22 compound treatment 1196836.0 395000.0 0.84 1071143.0 323000.0 0.74 1.1125 0.9979 1572963 ChemDiv2_004774 Fc1cc(F)c(F)c(OCc2ccc(o2)C(=O)NCCc3c[nH]c4ccccc34)c1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I23 mock treatment 1137045.0 335000.0 0.71 960907.0 213000.0 0.48 0.8457 0.9825 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 I24 mock treatment 821925.0 20300.0 0.04 764465.0 16800.0 0.04 0.0575 0.9981 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J01 compound treatment 941574.0 140000.0 0.3 1016125.0 268000.0 0.61 0.6414 0.9451 1985994 ChemDiv2_004775 CCn1ccc(n1)C(=O)NC2=C(CCC2)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J02 compound treatment 898808.0 97200.0 0.21 1028729.0 281000.0 0.64 0.5976 0.89 1985995 ChemDiv2_004776 CN(C1CCCCC1)C(=O)COc2ccc(cc2)c3nn(C)c(=O)c4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J03 compound treatment 1012219.0 211000.0 0.45 1143037.0 395000.0 0.9 0.9513 0.9479 1985996 ChemDiv2_004777 COc1ccc2c(NCC3=CC=CC3)cc(C)nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J04 compound treatment 983607.0 182000.0 0.39 1150154.0 402000.0 0.92 0.9199 0.9263 1985997 ChemDiv2_004778 CC(C)Nc1nc(Oc2ccc(=O)n(n2)c3ccccc3)nc(n1)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J05 compound treatment 1129386.0 328000.0 0.69 1071392.0 324000.0 0.74 1.0118 0.9996 1985998 ChemDiv2_004779 Cc1cccc(c1)n2c(SCC(=O)Nc3ccccc3)nc4nc5CC(C)(C)OCc5cc4c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J06 compound treatment 1281609.0 480000.0 1.02 1258495.0 511000.0 1.16 1.5408 0.9978 1985999 ChemDiv2_004780 CN(C)c1nc(nc(n1)C(=O)Nc2ccccc2)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J07 compound treatment 1339205.0 538000.0 1.14 1207378.0 460000.0 1.05 1.5449 0.9991 1986000 ChemDiv2_004781 CCCCn1c(NCCO)nc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J08 compound treatment 1303717.0 502000.0 1.06 1480757.0 733000.0 1.67 1.9312 0.9765 1986001 ChemDiv2_004782 Oc1c2C(C3=C(CCCC3=O)Nc2nn1c4ccccc4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J09 compound treatment 1146382.0 345000.0 0.73 1149814.0 402000.0 0.91 1.1633 0.9939 1986002 ChemDiv2_004783 CCC(c1nc(no1)c2ccncc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J10 compound treatment 1499922.0 698000.0 1.48 1715183.0 967000.0 2.2 2.6022 0.9814 1986003 ChemDiv2_004784 COc1cc2CCN(Cc2cc1OC)C(=O)CSc3nc4[nH]ncc4c(=O)n3c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J11 compound treatment 1336313.0 535000.0 1.13 1589873.0 842000.0 1.91 2.1555 0.9687 1986004 ChemDiv2_004785 Nc1ccc(cc1)C(=O)Nc2ccc3[nH]c(nc3c2)c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J12 compound treatment 1488400.0 687000.0 1.46 1611081.0 863000.0 1.96 2.4176 0.9892 1986005 ChemDiv2_004786 COc1ccc(Nc2oc(COc3ccccc3F)nc2C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J13 compound treatment 1111622.0 310000.0 0.66 1627883.0 880000.0 2.0 1.8798 0.8924 1986006 ChemDiv2_004787 CCOCC(=O)Nc1cc(C)on1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J14 compound treatment 1101829.0 300000.0 0.64 1801406.0 1050000.0 2.4 2.1441 0.865 1986007 ChemDiv2_004788 CCOC(=O)c1oc2ccccc2c1CSc3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J15 compound treatment 1538356.0 737000.0 1.56 1489641.0 742000.0 1.69 2.2972 0.9993 1986008 ChemDiv2_004789 CNc1ncnc2sc(C)c(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J16 compound treatment 1265188.0 464000.0 0.98 1433627.0 686000.0 1.56 1.7977 0.9752 1986009 ChemDiv2_004790 CCN1C(=O)C2(N(CCN3CCOCC3)C(=O)C(=C2C(=O)c4ccc(F)cc4)O)c5ccccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J17 compound treatment 1175093.0 374000.0 0.79 1162583.0 415000.0 0.94 1.2269 0.9962 1986010 ChemDiv2_004791 CCS(=O)(=O)c1nc2ccccc2n1Cc3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J18 compound treatment 1158822.0 357000.0 0.76 1239680.0 492000.0 1.12 1.3265 0.982 1986011 ChemDiv2_004792 Cc1ccc(CNc2nc(N)n(n2)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J19 compound treatment 1138478.0 337000.0 0.71 964951.0 217000.0 0.49 0.8543 0.9838 1986012 ChemDiv2_004793 CCOC(=O)N1CCC(CC1)Nc2nc(nc(n2)N3CCCC3)N4CCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J20 compound treatment 1184647.0 383000.0 0.81 976174.0 228000.0 0.52 0.9416 0.9767 1986013 ChemDiv2_004794 COc1ccccc1NC(=O)C2C3C4CCCCC4(NC2=O)Oc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J21 compound treatment 1126972.0 325000.0 0.69 904192.0 157000.0 0.36 0.7394 0.9526 1986014 ChemDiv2_004795 O=C(CN1C(=O)c2cccc3cccc1c23)NC4CCCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J22 compound treatment 1082698.0 281000.0 0.6 925409.0 178000.0 0.4 0.7071 0.9821 1986015 ChemDiv2_004796 COc1cccc(CNCCc2c[nH]c3ccccc23)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J23 mock treatment 957301.0 156000.0 0.33 839664.0 92000.0 0.21 0.3813 0.9757 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 J24 mock treatment 718451.0 -83100.0 -0.18 636873.0 -111000.0 -0.25 -0.3028 -0.9847 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K01 compound treatment 662401.0 -139000.0 -0.3 610122.0 -138000.0 -0.31 -0.4298 -0.9996 1986016 ChemDiv2_004797 CC(Sc1nnc2n(C)c3ccccc3n12)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K02 compound treatment 990119.0 189000.0 0.4 888158.0 140000.0 0.32 0.5084 0.9938 1986017 ChemDiv2_004798 CCN(CC)c1nc(C)nc2c3cc4COC(C)(C)Cc4nc3sc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K03 compound treatment 1066314.0 265000.0 0.56 1063086.0 315000.0 0.72 0.9039 0.9927 1986018 ChemDiv2_004799 Oc1ccc(cc1)C2C3=C(CCCC3=O)Nc4ccc5ccccc5c24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K04 compound treatment 1088789.0 287000.0 0.61 1094128.0 346000.0 0.79 0.9875 0.9919 1986019 ChemDiv2_004800 COc1ccc(CNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K05 compound treatment 1061835.0 260000.0 0.55 948819.0 201000.0 0.46 0.7135 0.9956 1412400 ChemDiv2_004801 OCCNc1cc(nc(n1)c2ccc(Br)cc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K06 compound treatment 1258830.0 457000.0 0.97 1207224.0 460000.0 1.04 1.4242 0.9993 1986020 ChemDiv2_004802 Cc1ccc2n(CCN3CCOCC3)c4nc5ccccc5nc4c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K07 compound treatment 1192895.0 391000.0 0.83 1105392.0 358000.0 0.81 1.1617 1.0 1262411 ChemDiv2_004803 O=C(Nc1ccc(Oc2ccc(NC(=O)c3cnccn3)cc2)cc1)c4cnccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K08 compound treatment 1282780.0 481000.0 1.02 1166220.0 419000.0 0.95 1.3942 0.9994 1986021 ChemDiv2_004804 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4cccnc4)C(=O)c5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K09 compound treatment 1199068.0 397000.0 0.84 1406852.0 659000.0 1.5 1.6555 0.9629 1240871 ChemDiv2_004805 CCOC(=O)Cc1csc(NC(=O)C2CCCCC2C(=O)O)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K10 compound treatment 1464391.0 663000.0 1.41 1398002.0 650000.0 1.48 2.039 0.9997 1871768 ChemDiv2_004806 COc1cc(OC)cc(c1)C(=O)N(CC=C)c2nnc(s2)c3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K11 compound treatment 1180621.0 379000.0 0.8 1285113.0 537000.0 1.22 1.4322 0.9793 1986022 ChemDiv2_004807 O=C(NCc1cccc(CNC(=O)c2cnccn2)c1)c3cnccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K12 compound treatment 1489834.0 688000.0 1.46 1162569.0 415000.0 0.94 1.6987 0.9777 1986023 ChemDiv2_004808 CC(C1SC(=O)NC1=O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K13 compound treatment 1213083.0 412000.0 0.87 1186921.0 439000.0 1.0 1.323 0.9977 1882179 ChemDiv2_004809 COC(=O)c1sccc1NC(=O)C2c3ccccc3Oc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K14 compound treatment 1293624.0 492000.0 1.04 1066081.0 318000.0 0.72 1.2495 0.9841 1986024 ChemDiv2_004810 O=C(Cn1nnc2sc3CCCCc3c2c1=O)NC4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K15 compound treatment 1330648.0 529000.0 1.12 1262565.0 515000.0 1.17 1.6208 0.9998 1986025 ChemDiv2_004811 CC(C)Cn1c(CCC(=O)O)ccc1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K16 compound treatment 1077564.0 276000.0 0.59 1162548.0 415000.0 0.94 1.0807 0.9736 1986026 ChemDiv2_004812 CCC(C)Nc1nc(SCC(=O)OC)nc(n1)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K17 compound treatment 1042214.0 241000.0 0.51 1037770.0 290000.0 0.66 0.8271 0.9919 1986027 ChemDiv2_004813 Clc1ccc(cc1)N2Cc3ccccc3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K18 compound treatment 1081274.0 280000.0 0.59 1061658.0 314000.0 0.71 0.924 0.9957 1882583 ChemDiv2_004814 Nc1cc(=O)nc(SCC(=O)Nc2ccccc2)n1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K19 compound treatment 1088618.0 287000.0 0.61 1121920.0 374000.0 0.85 1.0319 0.9865 1312784 ChemDiv2_004815 CCOC(=O)CSc1nc(SCC(=O)OCC)c2c3CCCCc3[nH]c2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K20 compound treatment 1111616.0 310000.0 0.66 1019122.0 271000.0 0.62 0.9011 0.9995 1380378 ChemDiv2_004816 CCN1CC2(OC3C=C2)C(C3C(=O)O)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K21 compound treatment 1120098.0 319000.0 0.68 1185901.0 438000.0 1.0 1.182 0.9821 1986028 ChemDiv2_004817 CCOC(=O)CCc1c(C)nc(SCCCn2c(=O)[nH]c3ccccc23)c(C#N)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K22 compound treatment 1118858.0 317000.0 0.67 921703.0 174000.0 0.4 0.7554 0.968 1986029 ChemDiv2_004818 CCn1ncc(Br)c1C(=O)NC2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K23 mock treatment 1029037.0 227000.0 0.48 1034298.0 287000.0 0.65 0.8017 0.989 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 K24 mock treatment 750391.0 -51200.0 -0.11 768391.0 20700.0 0.05 -0.0435 -0.3674 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L01 compound treatment 724730.0 -76800.0 -0.16 579544.0 -168000.0 -0.38 -0.3855 -0.9277 1986030 ChemDiv2_004819 CCn1ccc(n1)C(=O)Nc2ccc(Cl)cn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L02 compound treatment 1084627.0 283000.0 0.6 877808.0 130000.0 0.3 0.6335 0.9469 1986031 ChemDiv2_004820 COC(=O)COc1ccc(cc1)c2nn(C)c(=O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L03 compound treatment 1127657.0 326000.0 0.69 953699.0 206000.0 0.47 0.82 0.982 1986032 ChemDiv2_004821 CC(=O)Nc1cccc(Oc2nc(C)nc3sc4CCCc4c23)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L04 compound treatment 1125914.0 324000.0 0.69 1038061.0 290000.0 0.66 0.953 0.9998 1986033 ChemDiv2_004822 CCNc1nc(Oc2ccc(OCC)nn2)nc(n1)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L05 compound treatment 1122874.0 321000.0 0.68 971991.0 224000.0 0.51 0.8422 0.9898 1986034 ChemDiv2_004823 CC(C)OC(=O)C1C2OC3(CN(CC4CCCO4)C(=O)C13)C=C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L06 compound treatment 1274720.0 473000.0 1.0 1005787.0 258000.0 0.59 1.1242 0.9674 1986035 ChemDiv2_004824 CN(C)c1nc(nc(n1)C(=O)OCCO)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L07 compound treatment 1163663.0 362000.0 0.77 999654.0 252000.0 0.57 0.9478 0.9896 1986036 ChemDiv2_004825 Cc1ccc(cc1)c2cc(C(=O)OCC(=O)Nc3ccc(cc3)S(=O)(=O)N)c4ccccc4n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L08 compound treatment 1306422.0 505000.0 1.07 1123209.0 376000.0 0.85 1.3605 0.9937 1986037 ChemDiv2_004826 Cc1ccc(cc1)c2nc(Nc3nc(C)cc(C)n3)n[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L09 compound treatment 1174433.0 373000.0 0.79 1096076.0 348000.0 0.79 1.119 1.0 1986038 ChemDiv2_004827 NC(=O)COc1ccc(cc1)c2noc(COc3ccccc3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L10 compound treatment 1260270.0 459000.0 0.97 1203751.0 456000.0 1.04 1.4208 0.9995 1986039 ChemDiv2_004828 COCCn1c2NC3=C(C(c4ccccc4)c2c(=O)[nH]c1=O)C(=O)c5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L11 compound treatment 1314744.0 513000.0 1.09 1338575.0 591000.0 1.34 1.7192 0.9945 1986040 ChemDiv2_004829 Nc1cccc(c1)C(=O)Nc2ccc3[nH]c(nc3c2)c4ccccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L12 compound treatment 1625264.0 824000.0 1.75 1807928.0 1060000.0 2.41 2.9392 0.9875 1986041 ChemDiv2_004830 Oc1ccc(CN2CCCc3ccccc23)c4cccnc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L13 compound treatment 1199961.0 398000.0 0.84 1101145.0 353000.0 0.8 1.1654 0.9997 1986042 ChemDiv2_004831 CCN(CC)S(=O)(=O)c1ccc(NC(=O)Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L14 compound treatment 1256828.0 455000.0 0.97 1219875.0 472000.0 1.07 1.4415 0.9986 1451904 ChemDiv2_004832 COc1cc2c(C(=O)N3CCN(C)CC3)c(C)oc2cc1Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L15 compound treatment 1281814.0 480000.0 1.02 1095498.0 348000.0 0.79 1.279 0.9922 1986043 ChemDiv2_004833 Brc1ccc(cc1)N2OC3C(C2c4cccnc4)C(=O)N(C5CCCCC5)C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L16 compound treatment 1194412.0 393000.0 0.83 955525.0 208000.0 0.47 0.923 0.964 1986044 ChemDiv2_004834 CCCN1C(=O)C2(N(CCN(C)C)C(=O)C(=C2C(=O)c3ccc(F)cc3)O)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L17 compound treatment 1204944.0 403000.0 0.86 1121374.0 374000.0 0.85 1.2054 1.0 1986045 ChemDiv2_004835 CCN(CC)C(=O)Cn1c(nc2ccccc12)S(=O)(=O)CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L18 compound treatment 1188197.0 387000.0 0.82 1035531.0 288000.0 0.65 1.0423 0.9938 1986046 ChemDiv2_004836 Nc1nc(NCc2ccco2)nn1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L19 compound treatment 1212467.0 411000.0 0.87 878104.0 130000.0 0.3 0.8256 0.8972 1986047 ChemDiv2_004837 O=C(CN1C(=O)c2cccc3cccc1c23)N4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L20 compound treatment 1138178.0 337000.0 0.71 928726.0 181000.0 0.41 0.7956 0.9658 1986048 ChemDiv2_004838 Brc1ccc(NC(=O)C2C3C4CCCCC4(NC2=O)Oc5ccccc35)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L21 compound treatment 1089514.0 288000.0 0.61 1020999.0 273000.0 0.62 0.871 1.0 1986049 ChemDiv2_004839 C=CCNC(=O)c1ccccc1NC(=O)CN2C(=O)c3cccc4cccc2c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L22 compound treatment 1096128.0 295000.0 0.62 1111104.0 363000.0 0.83 1.0258 0.9905 1986050 ChemDiv2_004840 CN(C)c1nc(N)nc(CSc2nnc(c3cccnc3)n2CC=C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L23 mock treatment 1012429.0 211000.0 0.45 1167153.0 419000.0 0.95 0.9904 0.9404 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 L24 mock treatment 781725.0 -19900.0 -0.04 600215.0 -147000.0 -0.34 -0.2668 -0.7897 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M01 compound treatment 818675.0 17100.0 0.04 552000.0 -196000.0 -0.44 -0.289 -0.6474 1986051 ChemDiv2_004841 OC(=O)CSc1nnc2n(CCOc3ccccc3)c4ccccc4n12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M02 compound treatment 1107714.0 306000.0 0.65 1182468.0 435000.0 0.99 1.1579 0.9792 1986052 ChemDiv2_004842 Oc1cccc(c1)N2Cc3ccccc3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M03 compound treatment 1150780.0 349000.0 0.74 1099807.0 352000.0 0.8 1.0895 0.9992 1986053 ChemDiv2_004843 Cc1cc(NC(=O)Cc2ccc(C)cc2)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M04 compound treatment 1199634.0 398000.0 0.84 993357.0 246000.0 0.56 0.9916 0.9799 1452141 ChemDiv2_004844 CN(C)C(=O)C1Cc2ccccc2CN1S(=O)(=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M05 compound treatment 1136986.0 335000.0 0.71 1067295.0 320000.0 0.73 1.0166 0.9999 1134920 ChemDiv2_004845 COc1ccc(cc1OC)C(=O)Oc2cccc3cccnc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M06 compound treatment 1352874.0 551000.0 1.17 987248.0 240000.0 0.54 1.2115 0.9396 1986054 ChemDiv2_004846 Cc1ccc2n(CC#N)c3nc4ccccc4nc3c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M07 compound treatment 1364628.0 563000.0 1.19 970068.0 222000.0 0.51 1.2015 0.9269 1510264 ChemDiv2_004847 COc1ccccc1N2CCN(CC2)C(=O)CCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M08 compound treatment 1257311.0 456000.0 0.97 1114453.0 367000.0 0.83 1.2728 0.9973 1986055 ChemDiv2_004848 Nc1nc(COc2cccc3cccnc23)nc(Nc4ccccc4)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M09 compound treatment 1338600.0 537000.0 1.14 918976.0 171000.0 0.39 1.0804 0.8979 1986056 ChemDiv2_004849 Cc1onc(c1C(=O)Nc2ccn(Cc3ccc(C)cc3)n2)c4ccccc4Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M10 compound treatment 1336629.0 535000.0 1.13 1319855.0 572000.0 1.3 1.7219 0.9977 1986057 ChemDiv2_004850 CC(=O)OC(C(=O)Nc1nccs1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M11 compound treatment 1356765.0 555000.0 1.18 998223.0 251000.0 0.57 1.235 0.9445 1881582 ChemDiv2_004851 CCOc1ccccc1c2cc(C(=O)Nc3ccon3)c4ccccc4n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M12 compound treatment 1423089.0 622000.0 1.32 1442825.0 695000.0 1.58 2.0492 0.9959 1986058 ChemDiv2_004852 O=c1[nH]c2SC3C4CCC(C4)C3C(c2s1)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M13 compound treatment 1254971.0 453000.0 0.96 1061766.0 314000.0 0.71 1.1846 0.9893 1986059 ChemDiv2_004853 COc1ccc(cc1)n2cc3n(C)c(=O)n(C)c(=O)c3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M14 compound treatment 1247379.0 446000.0 0.95 940470.0 193000.0 0.44 0.9782 0.939 1986060 ChemDiv2_004854 CC(C)Cc1nnc(NS(=O)(=O)c2ccccc2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M15 compound treatment 1207811.0 406000.0 0.86 1167575.0 420000.0 0.95 1.284 0.9987 1986061 ChemDiv2_004855 OC(=O)CCc1ccc(c2ccccc2)n1CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M16 compound treatment 1141151.0 340000.0 0.72 1188362.0 441000.0 1.0 1.2175 0.9869 1986062 ChemDiv2_004856 C=CCOc1ccc(cc1)C(=O)N(Cc2ccccc2)C3CCS(=O)(=O)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M17 compound treatment 881581.0 80000.0 0.17 1007325.0 260000.0 0.59 0.5373 0.8749 1259552 ChemDiv2_004857 Brc1cccc(c1)N2Cc3ccccc3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M18 compound treatment 1124181.0 323000.0 0.68 1167840.0 420000.0 0.96 1.159 0.9866 1882604 ChemDiv2_004858 Nc1cc(=O)nc(SCC(=O)NC2CCCCC2)n1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M19 compound treatment 1200113.0 399000.0 0.84 939563.0 192000.0 0.44 0.9059 0.9527 1986063 ChemDiv2_004859 CC1(C)Cc2c(CO1)c(nc3sc(c(N)c23)c4ccc(o4)C(=O)O)N5CCOCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M20 compound treatment 1106647.0 305000.0 0.65 1032509.0 285000.0 0.65 0.9152 1.0 1705917 ChemDiv2_004860 CN1CC2(OC3C=C2)C(C3C(=O)O)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M21 compound treatment 1163641.0 362000.0 0.77 1195487.0 448000.0 1.02 1.2626 0.9903 1986064 ChemDiv2_004861 Cc1cc(NC(=O)c2sc(NCC=C)nc2N)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M22 compound treatment 1117094.0 316000.0 0.67 1178269.0 431000.0 0.98 1.1652 0.9828 1311215 ChemDiv2_004862 CN(C)S(=O)(=O)c1cc(C(=O)N2CCN(Cc3ccccc3)CC2)c(Cl)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M23 mock treatment 965175.0 164000.0 0.35 1162675.0 415000.0 0.94 0.9124 0.9077 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 M24 mock treatment 723056.0 -78500.0 -0.17 584309.0 -163000.0 -0.37 -0.3804 -0.9344 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N01 compound treatment 801077.0 -502.0 0.0 480830.0 -267000.0 -0.61 -0.4298 -0.7083 1986065 ChemDiv2_004863 Clc1cnn(Cc2cccc(c2)C(=O)Nc3nc4ccc(Cl)cc4s3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N02 compound treatment 1212460.0 411000.0 0.87 906321.0 159000.0 0.36 0.8709 0.9238 1986066 ChemDiv2_004864 Cn1nc(c2ccc(cc2)C(=O)O)c3ccccc3c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N03 compound treatment 1212773.0 411000.0 0.87 1171416.0 424000.0 0.96 1.2976 0.9988 1986067 ChemDiv2_004865 OCCN1CCN(CC1)C(=O)c2cccc(F)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N04 compound treatment 1308975.0 507000.0 1.08 1017939.0 270000.0 0.61 1.1951 0.9647 1986068 ChemDiv2_004866 CC(C)(C)Nc1nc(Oc2ccc(=O)n(n2)c3ccccc3)nc(n1)N4CCOCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N05 compound treatment 1217127.0 416000.0 0.88 990583.0 243000.0 0.55 1.0134 0.9747 1986069 ChemDiv2_004867 COC(=O)C1C2OC3(CN(CCc4ccccc4)C(=O)C13)C=C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N06 compound treatment 1296630.0 495000.0 1.05 1159141.0 411000.0 0.94 1.4036 0.9984 1986070 ChemDiv2_004868 CCNc1nc(nc(n1)C(=O)O)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N07 compound treatment 1383714.0 582000.0 1.23 1200231.0 453000.0 1.03 1.6002 0.9959 1986071 ChemDiv2_004869 Cc1cc(C)nc(SCCC(=O)OCN2C(=O)c3ccccc3C2=O)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N08 compound treatment 1400680.0 599000.0 1.27 1188791.0 441000.0 1.0 1.6072 0.9932 1986072 ChemDiv2_004870 Cc1ccc(SCc2cc(=O)n3ncnc3[nH]2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N09 compound treatment 1402528.0 601000.0 1.27 1214942.0 467000.0 1.06 1.652 0.9959 1986073 ChemDiv2_004871 NC(=O)COc1ccc(cc1)c2noc(n2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N10 compound treatment 1441472.0 640000.0 1.36 1226349.0 479000.0 1.09 1.7287 0.994 1986074 ChemDiv2_004872 CCn1c2NC3=C(C(c4ccccc4)c2c(=O)[nH]c1=O)C(=O)c5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N11 compound treatment 1422929.0 621000.0 1.32 1100855.0 353000.0 0.8 1.4992 0.9718 1986075 ChemDiv2_004873 Fc1ccccc1C(=O)Nc2ccc3[nH]c(nc3c2)c4ccccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N12 compound treatment 1544923.0 743000.0 1.58 1262864.0 515000.0 1.17 1.9425 0.9893 1986076 ChemDiv2_004874 CCC1(C)Cc2ccccc2-c3nc(NCCO)n(c4ccccc4)c(=O)c31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N13 compound treatment 1411860.0 610000.0 1.29 1328152.0 580000.0 1.32 1.848 1.0 1986077 ChemDiv2_004875 CCn1c(NCc2ccc(Br)cc2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N14 compound treatment 1274826.0 473000.0 1.0 1245901.0 498000.0 1.13 1.5104 0.9982 1784157 ChemDiv2_004876 COc1ccc2n(C)c(C)c(C(=O)N3CCN(C)CC3)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N15 compound treatment 1358220.0 557000.0 1.18 1246955.0 499000.0 1.14 1.6371 0.9998 1986078 ChemDiv2_004877 Cc1cc(C)n2c(SCCN3C(=O)c4ccccc4C3=O)nnc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N16 compound treatment 1149335.0 348000.0 0.74 1222612.0 475000.0 1.08 1.2848 0.9827 1986079 ChemDiv2_004878 CN1C(=O)C2(N(CC3CCCO3)C(=O)C(=C2C(=O)c4ccc(Cl)cc4)O)c5ccccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N17 compound treatment 1302193.0 501000.0 1.06 1326945.0 579000.0 1.32 1.6817 0.9943 1693306 ChemDiv2_004879 Cn1c(SCC(=O)NC(c2ccccc2)c3ccccc3)nc4n(C)c(=O)n(C)c(=O)c14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N18 compound treatment 1464546.0 663000.0 1.41 1230693.0 483000.0 1.1 1.7703 0.9925 1986080 ChemDiv2_004880 Nc1nc(NCc2cccs2)nn1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N19 compound treatment 1187723.0 386000.0 0.82 1118159.0 370000.0 0.84 1.1744 0.9999 1986081 ChemDiv2_004881 CCOc1ccc(NC(=O)CN2C(=O)c3cccc4cccc2c34)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N20 compound treatment 1173076.0 371000.0 0.79 1113639.0 366000.0 0.83 1.1452 0.9996 1986082 ChemDiv2_004882 CC(C)NCc1nc(no1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N21 compound treatment 1283097.0 482000.0 1.02 1113231.0 366000.0 0.83 1.3095 0.9948 1986083 ChemDiv2_004883 COc1ccc(CCNC(=O)CN2C(=O)c3cccc4cccc2c34)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N22 compound treatment 1305210.0 504000.0 1.07 1000219.0 253000.0 0.57 1.1609 0.9577 1986084 ChemDiv2_004884 Nc1nc(Cc2cc3ccccc3[nH]2)nc(NC4CCCCC4)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N23 mock treatment 1278382.0 477000.0 1.01 1021855.0 274000.0 0.62 1.1555 0.973 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 N24 mock treatment 785049.0 -16500.0 -0.04 702719.0 -45000.0 -0.1 -0.0971 -0.8982 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O01 compound treatment 769642.0 -31900.0 -0.07 449767.0 -298000.0 -0.68 -0.5268 -0.7739 1986085 ChemDiv2_004885 CN(C)S(=O)(=O)c1ccc2[nH]c(=O)[nH]c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O02 compound treatment 1271123.0 470000.0 1.0 940819.0 193000.0 0.44 1.0143 0.9323 1986086 ChemDiv2_004886 Cc1nnc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O03 compound treatment 1124161.0 323000.0 0.68 908200.0 161000.0 0.36 0.7416 0.9567 1986087 ChemDiv2_004887 COCc1nnc(NC(=O)c2cccc(NC(=O)C(C)C)c2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O04 compound treatment 1349108.0 548000.0 1.16 1003213.0 256000.0 0.58 1.2316 0.9488 1986088 ChemDiv2_004888 CN(C)CCSc1nnc2sc3ccccc3n12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O05 compound treatment 1495598.0 694000.0 1.47 974902.0 227000.0 0.52 1.4056 0.9014 1629645 ChemDiv2_004889 CC(Oc1ccc(Cl)cc1C)C(=O)n2cnc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O06 compound treatment 1348474.0 547000.0 1.16 1147828.0 400000.0 0.91 1.4631 0.9928 1237456 ChemDiv2_004890 Cc1c(C)c2ccccc2n1CC(O)CNC(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O07 compound treatment 1308838.0 507000.0 1.08 968133.0 220000.0 0.5 1.1148 0.9396 1879686 ChemDiv2_004891 Cc1cccc(N2CCN(CC2)C(=O)CCCC(=O)O)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O08 compound treatment 1210077.0 408000.0 0.87 1019645.0 272000.0 0.62 1.0496 0.9864 1986089 ChemDiv2_004892 Cc1cccc(Nc2nc(N)nc(CSc3nccn3C)n2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O09 compound treatment 1414943.0 613000.0 1.3 1256601.0 509000.0 1.16 1.7376 0.9983 1881065 ChemDiv2_004893 CCn1c(NC(=O)c2cccc(Cn3cc(Cl)cn3)c2)nc4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O10 compound treatment 1398004.0 596000.0 1.26 1051060.0 303000.0 0.69 1.3818 0.9594 1986090 ChemDiv2_004894 COc1ccccc1N2CCN(CC2)C(=O)C(C)N3C(=O)c4ccccc4C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O11 compound treatment 1318910.0 517000.0 1.1 1003647.0 256000.0 0.58 1.187 0.9561 1696403 ChemDiv2_004895 COC(=O)c1cc(nc2ccccc12)c3cccc(N)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O12 compound treatment 1261935.0 460000.0 0.98 1353727.0 606000.0 1.38 1.6644 0.9857 1864300 ChemDiv2_004896 Cc1n[nH]c(=O)nc1NC2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O13 compound treatment 1387679.0 586000.0 1.24 1135692.0 388000.0 0.88 1.5024 0.9859 1986091 ChemDiv2_004897 CCOC(=O)Cn1cc2n(C)c(=O)n(C)c(=O)c2c1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O14 compound treatment 1249924.0 448000.0 0.95 1158272.0 411000.0 0.93 1.3322 1.0 1986092 ChemDiv2_004898 Cc1cc(O)n(n1)c2nc3ccccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O15 compound treatment 1286627.0 485000.0 1.03 1384719.0 637000.0 1.45 1.7512 0.9859 1986093 ChemDiv2_004899 OC(=O)CCc1ccc(c2ccc(F)cc2)n1Cc3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O16 compound treatment 1254910.0 453000.0 0.96 1394244.0 647000.0 1.47 1.719 0.9788 1986094 ChemDiv2_004900 Cc1ccc(cc1S(=O)(=O)N2CCCC2)c3nn(C)c(=O)c4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O17 compound treatment 1296868.0 495000.0 1.05 1026459.0 279000.0 0.63 1.1906 0.9708 1986095 ChemDiv2_004901 CCCOc1ccc(cc1)N2CC(CC2=O)C(=O)Nc3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O18 compound treatment 1081985.0 280000.0 0.59 1157253.0 410000.0 0.93 1.0788 0.9765 1876335 ChemDiv2_004902 CC(Sc1nc(=O)cc(N)n1c2ccccc2)C(=O)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O19 compound treatment 1509782.0 708000.0 1.5 937943.0 190000.0 0.43 1.3675 0.8752 1986096 ChemDiv2_004903 Cc1ccc(cc1)C2C=C(Nc3nc(nn23)N4C(=O)CCC4=O)c5ccc(Cl)cc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O20 compound treatment 1338612.0 537000.0 1.14 974238.0 227000.0 0.52 1.1692 0.9357 1986097 ChemDiv2_004904 CCOC(=O)c1sc(NC(=O)c2c(Br)cnn2CC)c(C#N)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O21 compound treatment 1172786.0 371000.0 0.79 957035.0 209000.0 0.48 0.893 0.971 1986098 ChemDiv2_004905 NC1=C(C#N)C(c2ccccc2Cl)c3c(O)ncnc3O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O22 compound treatment 1301164.0 500000.0 1.06 1042390.0 295000.0 0.67 1.2227 0.9756 1986099 ChemDiv2_004906 Cn1cc(Cl)c(n1)C(=O)NC2CCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O23 mock treatment 1082037.0 280000.0 0.59 1068316.0 321000.0 0.73 0.9359 0.9949 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 O24 mock treatment 570645.0 -231000.0 -0.49 518181.0 -230000.0 -0.52 -0.7151 -0.9995 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P01 compound treatment 537584.0 -264000.0 -0.56 444514.0 -303000.0 -0.69 -0.8831 -0.9947 1986100 ChemDiv2_004907 COc1ccc(CCNC(=O)c2nn(C)cc2Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P02 compound treatment 742442.0 -59100.0 -0.13 520982.0 -227000.0 -0.52 -0.4531 -0.8542 1986101 ChemDiv2_004908 CNC(=O)c1ccc(cc1)c2nn(C)c(=O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P03 compound treatment 1036175.0 235000.0 0.5 1144322.0 397000.0 0.9 0.9893 0.9607 1986102 ChemDiv2_004909 OCCN1CCN(CC1)C(=O)CCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P04 compound treatment 930313.0 129000.0 0.27 1135330.0 388000.0 0.88 0.8162 0.8846 1986103 ChemDiv2_004910 COc1nc(NCC(C)C)nc(Oc2ccc(OCc3ccccc3)nn2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P05 compound treatment 1056406.0 255000.0 0.54 1006660.0 259000.0 0.59 0.7983 0.9991 1986104 ChemDiv2_004911 OC(=O)C1C2OC3(CN(C4CCCC4)C(=O)C13)C=C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P06 compound treatment 926738.0 125000.0 0.27 1106029.0 358000.0 0.81 0.7637 0.8913 1986105 ChemDiv2_004912 Nc1nc(CN2CCc3ccccc3C2)nc(Nc4ccccc4)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P07 compound treatment 870945.0 69400.0 0.15 649564.0 -98100.0 -0.22 -0.0538 -0.2012 1986106 ChemDiv2_004913 Cc1n[nH]c(=O)nc1N2CCc3ccccc3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P08 compound treatment 838268.0 36700.0 0.08 728287.0 -19400.0 -0.04 0.0238 0.2662 1986107 ChemDiv2_004914 Clc1ccc(SCc2cc(=O)n3ncnc3[nH]2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P09 compound treatment 763615.0 -38000.0 -0.08 755452.0 7760.0 0.02 -0.0444 -0.5393 1986108 ChemDiv2_004915 COC(=O)c1ccc(COc2ccc(cc2OC)C3NC(CS3)C(=O)O)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P10 compound treatment 827159.0 25600.0 0.05 872114.0 124000.0 0.28 0.2384 0.8276 1986109 ChemDiv2_004916 Cc1cccc(c1)C2C3=C(Nc4c2c(=O)[nH]c(=O)n4C)c5ccccc5C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P11 compound treatment 738435.0 -63100.0 -0.13 687794.0 -59900.0 -0.14 -0.1909 -1.0 1986110 ChemDiv2_004917 CC(Oc1cccc(Cl)c1)c2nc(no2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P12 compound treatment 707843.0 -93700.0 -0.2 644246.0 -103000.0 -0.24 -0.3068 -0.9965 1986111 ChemDiv2_004918 CCC1(C)Cc2ccccc2-c3nc(c4ccccc4)n(CCO)c(=O)c31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P13 compound treatment 754356.0 -47200.0 -0.1 676372.0 -71300.0 -0.16 -0.1854 -0.9731 1986112 ChemDiv2_004919 CC(C)n1c(NCc2ccc(cc2)N(C)C)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P14 compound treatment 831792.0 30200.0 0.06 867755.0 120000.0 0.27 0.2383 0.8499 1986113 ChemDiv2_004920 COc1ccc(OC)c(c1)C(=O)c2oc3ccc(OC)cc3c2N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P15 compound treatment 907097.0 106000.0 0.22 950463.0 203000.0 0.46 0.4842 0.9449 1986114 ChemDiv2_004921 Cc1nnc(SCCN2C(=O)c3ccccc3C2=O)nc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P16 compound treatment 842565.0 41000.0 0.09 969956.0 222000.0 0.51 0.4188 0.8167 1986115 ChemDiv2_004922 Cc1ccc(cc1F)C(=O)C2=C(O)C(=O)N(CCCN3CCOCC3)C42C(=O)N(CC=C)c5ccccc54 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P17 compound treatment 815125.0 13500.0 0.03 954990.0 207000.0 0.47 0.3536 0.7488 1211907 ChemDiv2_004923 Cn1c(SCC(=O)Nc2ccccc2)nc3n(C)c(=O)n(C)c(=O)c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P18 compound treatment 774330.0 -27200.0 -0.06 760917.0 13200.0 0.03 -0.0196 -0.3007 1986116 ChemDiv2_004924 Nc1nc2ccccc2n1C(=O)CCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P19 compound treatment 966815.0 165000.0 0.35 687619.0 -60100.0 -0.14 0.1511 0.4019 1986117 ChemDiv2_004925 CCN(CC)C(=O)CN1C(=O)c2cccc3cccc1c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P20 compound treatment 767356.0 -34200.0 -0.07 741797.0 -5890.0 -0.01 -0.0608 -0.8238 1986118 ChemDiv2_004926 CC(C)N(Cc1nc2ccccc2[nH]1)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P21 compound treatment 788103.0 -13500.0 -0.03 696695.0 -51000.0 -0.12 -0.1022 -0.8558 1673682 ChemDiv2_004927 OC(=O)CC1SC(=O)NC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P22 compound treatment 731188.0 -70400.0 -0.15 681477.0 -66200.0 -0.15 -0.212 -1.0 1986119 ChemDiv2_004928 O=C1N(C(=O)c2ccccc12)c3nc4[nH]c(cc(=O)n4n3)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P23 mock treatment 548974.0 -253000.0 -0.54 545949.0 -202000.0 -0.46 -0.703 -0.997 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1382 P24 mock treatment 509122.0 -292000.0 -0.62 407221.0 -340000.0 -0.77 -0.9858 -0.9939 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A01 compound treatment 350096.0 -355000.0 -0.75 406580.0 -364000.0 -0.83 -1.1171 -0.9989 1409745 IFLab1_003521 O=C(NCc1ccc2OCOc2c1)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A02 compound treatment 411432.0 -294000.0 -0.62 482517.0 -288000.0 -0.65 -0.9031 -0.9997 1784445 IFLab1_003522 CC/C(=C(\C#N)/c1nc2ccccc2[nH]1)/O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A03 compound treatment 407794.0 -298000.0 -0.63 732602.0 -37500.0 -0.09 -0.5065 -0.7955 2067605 IFLab1_003523 Cc1ccc(/C=N/c2sc(C)c(C)c2C#N)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A04 compound treatment 465592.0 -240000.0 -0.51 773210.0 3060.0 0.01 -0.3546 -0.6974 2067606 IFLab1_003524 COC1CS(=O)(=O)CC1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A05 compound treatment 487750.0 -218000.0 -0.46 511078.0 -259000.0 -0.59 -0.7428 -0.9927 1227048 IFLab1_003525 CC1CN(CCN1C(=O)c2cccc(Cl)c2)C(=O)c3cccc(Cl)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A06 compound treatment 422743.0 -283000.0 -0.6 546182.0 -224000.0 -0.51 -0.7838 -0.9967 1326007 IFLab1_003526 COc1cccc2cc(c3nnc(Nc4ccccc4F)s3)c(=O)oc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A07 compound treatment 463644.0 -242000.0 -0.51 767630.0 -2520.0 -0.01 -0.3665 -0.715 1345083 IFLab1_003527 O=C(Nc1ccncc1NC(=O)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A08 compound treatment 382222.0 -323000.0 -0.69 695968.0 -74200.0 -0.17 -0.6037 -0.8556 1656482 IFLab1_003528 Clc1cccc(c1)C2SCCN2C(=O)c3cc4ccccc4oc3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A09 compound treatment 513028.0 -192000.0 -0.41 597827.0 -172000.0 -0.39 -0.5654 -0.9998 1520132 IFLab1_003529 CC(C)N(C(=O)Cn1cnc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A10 compound treatment 520759.0 -185000.0 -0.39 548542.0 -222000.0 -0.5 -0.6331 -0.9922 1637825 IFLab1_003530 COC(=O)c1sc2ccccc2c1NC(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A11 compound treatment 457379.0 -248000.0 -0.53 825100.0 54900.0 0.12 -0.2835 -0.5245 1230553 IFLab1_003531 Clc1ccc(OCc2nc3ccccc3[nH]2)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A12 compound treatment 402361.0 -303000.0 -0.64 693024.0 -77100.0 -0.18 -0.5783 -0.8683 2067607 IFLab1_003532 FC(F)(F)c1cccc(c1)C(=O)Nc2ccccc2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A13 compound treatment 528470.0 -177000.0 -0.38 652816.0 -117000.0 -0.27 -0.4539 -0.9861 1243864 IFLab1_003533 COc1ccc(NC(=O)CSc2nc(C)cc(=O)[nH]2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A14 compound treatment 642273.0 -63100.0 -0.13 609319.0 -161000.0 -0.37 -0.3532 -0.9071 2067608 IFLab1_003534 CCNc1nc(NCC)nc(SCC(=O)c2ccccc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A15 compound treatment 822176.0 117000.0 0.25 742277.0 -27900.0 -0.06 0.1302 0.5096 2067609 IFLab1_003535 C=CCn1nnnc1SCC(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A16 compound treatment 824995.0 120000.0 0.25 826952.0 56800.0 0.13 0.2706 0.951 1331694 IFLab1_003536 COc1ccc(cc1)c2cc3ccccn3c2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A17 compound treatment 900177.0 195000.0 0.41 844873.0 74700.0 0.17 0.4121 0.923 1166854 IFLab1_003537 C(N1CCN(CC1)c2ccccc2)c3cn4cccnc4n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A18 compound treatment 755166.0 49800.0 0.11 616959.0 -153000.0 -0.35 -0.1717 -0.4718 2067610 IFLab1_003538 O=C(Nc1nccs1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A19 compound treatment 929957.0 225000.0 0.48 809107.0 39000.0 0.09 0.3992 0.8245 2067611 IFLab1_003539 COc1ccc(cc1)C(=O)CNC2=NCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A20 compound treatment 1037657.0 332000.0 0.7 899432.0 129000.0 0.29 0.7059 0.9249 1700419 IFLab1_003540 CCOc1ccc(cc1)S(=O)(=O)NCCO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A21 compound treatment 734792.0 29400.0 0.06 632476.0 -138000.0 -0.31 -0.1773 -0.5555 1164353 IFLab1_003541 OC(=O)CNC(=O)COc1cccc(Br)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A22 compound treatment 625332.0 -80100.0 -0.17 520314.0 -250000.0 -0.57 -0.5217 -0.88 1152002 IFLab1_003542 COc1ccccc1NC(=O)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A23 mock treatment 458658.0 -247000.0 -0.52 598613.0 -172000.0 -0.39 -0.6457 -0.9895 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 A24 mock treatment 441052.0 -264000.0 -0.56 444620.0 -326000.0 -0.74 -0.9196 -0.9906 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B01 compound treatment 439823.0 -266000.0 -0.56 545071.0 -225000.0 -0.51 -0.76 -0.9989 1677123 IFLab1_003543 Cc1cc(=O)cc(C)n1c2ccc(cc2)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B02 compound treatment 1074188.0 369000.0 0.78 1004889.0 235000.0 0.53 0.9302 0.9827 2067612 IFLab1_003544 CC(=C)C(=O)Oc1ccc(cc1)N2C(=O)C3C4CC(C=C4)C3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B03 compound treatment 1110716.0 405000.0 0.86 1180372.0 410000.0 0.93 1.267 0.9992 1207063 IFLab1_003545 CCOC(=O)C1CCN(Cc2cc(Cl)c3cccnc3c2O)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B04 compound treatment 980639.0 275000.0 0.58 1251137.0 481000.0 1.09 1.1858 0.9567 1980352 IFLab1_003546 CCCc1nnc2SCC(=Nn12)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B05 compound treatment 1100411.0 395000.0 0.84 1279047.0 509000.0 1.16 1.4102 0.9874 1398133 IFLab1_003547 Cn1c(=NC(=O)c2nc3ccccc3s2)sc4cc(Cl)ccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B06 compound treatment 1140826.0 435000.0 0.92 1416920.0 647000.0 1.47 1.6925 0.9748 2067613 IFLab1_003548 COc1ccc(cc1)C(=O)CSc2nnc3CCCCCn23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B07 compound treatment 1009356.0 304000.0 0.64 1320148.0 550000.0 1.25 1.3398 0.9525 2067614 IFLab1_003549 O=C(Nc1ccc2sccc2c1)/C=C/c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B08 compound treatment 1132686.0 427000.0 0.91 1443729.0 674000.0 1.53 1.7234 0.9686 2067615 IFLab1_003550 CCc1ccc(/C=C/2\SC(=S)N(CCCC(=O)Nc3cccnc3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B09 compound treatment 933229.0 228000.0 0.48 1434063.0 664000.0 1.51 1.4088 0.889 1145470 IFLab1_003551 O=C(Nc1ccc(cc1)c2nc3ccccc3o2)C4CC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B10 compound treatment 1219375.0 514000.0 1.09 1334311.0 564000.0 1.28 1.6774 0.9967 2067616 IFLab1_003552 Cn1c(=NC(=O)c2ccc(Br)s2)sc3cc(F)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B11 compound treatment 1096781.0 391000.0 0.83 1254855.0 485000.0 1.1 1.3659 0.9902 1265904 IFLab1_003553 CCC(=O)Nc1ccc(cc1)c2nnc3CCCCCn23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B12 compound treatment 1174199.0 469000.0 0.99 1340796.0 571000.0 1.3 1.6201 0.9913 2067617 IFLab1_003554 NC(=O)c1ccc(N/C=C(\C#N)/c2nc(cs2)c3cccc4ccccc34)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B13 compound treatment 1086479.0 381000.0 0.81 1144783.0 375000.0 0.85 1.1735 0.9997 2067618 IFLab1_003555 CC(Sc1nnc(o1)c2cccc(Br)c2)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B14 compound treatment 974516.0 269000.0 0.57 1347604.0 577000.0 1.31 1.3317 0.9303 1134927 IFLab1_003556 CC(C)(C)NC(=O)C1C2CC(C)(NC1=O)Oc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B15 compound treatment 1015698.0 310000.0 0.66 1318397.0 548000.0 1.25 1.3465 0.9554 1650896 IFLab1_003557 CCOC(=O)c1c(C)[nH]c(C(=O)CC(=O)OC)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B16 compound treatment 1083955.0 379000.0 0.8 1148294.0 378000.0 0.86 1.1754 0.9994 1545249 IFLab1_003558 Cc1ccc(OCC(O)CN2CCCCC2)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B17 compound treatment 924261.0 219000.0 0.46 1220681.0 451000.0 1.02 1.0523 0.9359 2067619 IFLab1_003559 OC(=O)c1cccc(c1)N2C(=O)/C(=C\c3ccc4OCOc4c3)/SC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B18 compound treatment 1043515.0 338000.0 0.72 1076013.0 306000.0 0.7 0.9985 0.9999 1351386 IFLab1_003560 COc1ccccc1N2CCN(CC(O)COc3ccccc3CC=C)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B19 compound treatment 947650.0 242000.0 0.51 1231081.0 461000.0 1.05 1.1041 0.9461 1166032 IFLab1_003561 CC(C)c1ccc(OCC(C)NC(=O)c2cccs2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B20 compound treatment 923808.0 218000.0 0.46 1186266.0 416000.0 0.95 0.9963 0.946 1068756 IFLab1_003562 Cc1ccc(cc1)S(=O)(=O)CC(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B21 compound treatment 912991.0 208000.0 0.44 1152758.0 383000.0 0.87 0.9263 0.9502 1597132 IFLab1_003563 CCC(=O)Oc1ccc(cc1)N2C(=O)CCC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B22 compound treatment 938870.0 233000.0 0.49 965503.0 195000.0 0.44 0.664 0.9985 1604489 IFLab1_003564 O=S(=O)(N1CCc2ccccc12)c3cccc4cccnc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B23 mock treatment 911157.0 206000.0 0.44 940579.0 170000.0 0.39 0.5824 0.9983 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 B24 mock treatment 534382.0 -171000.0 -0.36 493469.0 -277000.0 -0.63 -0.7012 -0.9657 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C01 compound treatment 846355.0 141000.0 0.3 712776.0 -57400.0 -0.13 0.119 0.3651 1280715 IFLab1_003565 COc1ccc(Br)cc1S(=O)(=O)n2ccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C02 compound treatment 1096293.0 391000.0 0.83 1016703.0 247000.0 0.56 0.9823 0.9819 2067620 IFLab1_003566 FC(F)(F)SCC(=O)Nc1ccc(I)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C03 compound treatment 1179717.0 474000.0 1.01 1140205.0 370000.0 0.84 1.3059 0.9961 1475116 IFLab1_003567 COc1ccc2cc(ccc2c1)S(=O)(=O)N3CCN(C)CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C04 compound treatment 1148175.0 443000.0 0.94 1128245.0 358000.0 0.81 1.2394 0.9975 1224373 IFLab1_003568 OC1CS(=O)(=O)CC1N2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C05 compound treatment 1062322.0 357000.0 0.76 1159690.0 390000.0 0.89 1.1613 0.9969 1490334 IFLab1_003569 CC1CN(CCN1C(=O)c2ccccc2Cl)C(=O)c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C06 compound treatment 956459.0 251000.0 0.53 1252372.0 482000.0 1.1 1.1516 0.9449 1327035 IFLab1_003570 CCOc1cccc2cc(C(=O)N)c(=Nc3ccccc3F)oc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C07 compound treatment 1029940.0 325000.0 0.69 1170558.0 400000.0 0.91 1.1302 0.9905 1117794 IFLab1_003571 O=C(Nc1ccncc1NC(=O)C2CC2)C3CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C08 compound treatment 1130282.0 425000.0 0.9 1225122.0 455000.0 1.03 1.3683 0.9976 1303507 IFLab1_003572 CCC(=O)Nc1cccc(c1)c2cn3ccccc3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C09 compound treatment 979235.0 274000.0 0.58 1149183.0 379000.0 0.86 1.0198 0.9815 2067621 IFLab1_003573 CCCn1c(CCCO)nc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C10 compound treatment 1021178.0 316000.0 0.67 1267745.0 498000.0 1.13 1.2733 0.9686 1383855 IFLab1_003574 COC(=O)c1sc2ccccc2c1NC(=O)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C11 compound treatment 1071754.0 366000.0 0.78 1027739.0 258000.0 0.59 0.9633 0.9903 1142340 IFLab1_003575 COc1cc(Cn2c(nc3ccccc23)c4ccc(O)c(OC)c4)ccc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C12 compound treatment 1052905.0 347000.0 0.74 1199436.0 429000.0 0.98 1.211 0.9904 1385320 IFLab1_003576 O=C(Nc1ccccc1C#N)c2cc(=O)c3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C13 compound treatment 1023284.0 318000.0 0.67 1206054.0 436000.0 0.99 1.1773 0.9823 2067622 IFLab1_003577 Brc1ccc(NC2=Nc3ccccc3SC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C14 compound treatment 1150401.0 445000.0 0.94 1190200.0 420000.0 0.96 1.3423 1.0 1455353 IFLab1_003578 O=C(CSc1nc2ccccc2c(=O)n1c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C15 compound treatment 934937.0 230000.0 0.49 1125745.0 356000.0 0.81 0.9157 0.9705 1569227 IFLab1_003579 COc1ccc(cc1)C(=O)CSc2nnnn2CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C16 compound treatment 1076716.0 371000.0 0.79 1028804.0 259000.0 0.59 0.9724 0.9897 1182009 IFLab1_003580 CC(C)N(C(=O)CSc1ccccc1C(=O)O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C17 compound treatment 901304.0 196000.0 0.42 1181256.0 411000.0 0.93 0.9546 0.9333 2067623 IFLab1_003581 Cn1cnn2cc(c3ccccc3)[n+](C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C18 compound treatment 865145.0 160000.0 0.34 1119670.0 350000.0 0.79 0.8013 0.9277 1360104 IFLab1_003582 COc1ccccc1N2CCN(CC2)C(=O)Oc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C19 compound treatment 984989.0 280000.0 0.59 1049393.0 279000.0 0.63 0.868 0.9994 1730817 IFLab1_003583 COC(=O)c1ccccc1Sc2c(nc3ncccn23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C20 compound treatment 924879.0 219000.0 0.47 997728.0 228000.0 0.52 0.6948 0.9986 1207062 IFLab1_003584 OCCNS(=O)(=O)c1cc(Cl)ccc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C21 compound treatment 887430.0 182000.0 0.39 961861.0 192000.0 0.44 0.581 0.9982 1720395 IFLab1_003585 O=C(COc1cccc2ccccc12)OC3CCS(=O)(=O)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C22 compound treatment 922517.0 217000.0 0.46 1050468.0 280000.0 0.64 0.7761 0.9872 1409165 IFLab1_003586 COc1ccc(cc1)S(=O)(=O)N2C(C)CCCC2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C23 mock treatment 791196.0 85800.0 0.18 843060.0 72900.0 0.17 0.2458 0.9989 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 C24 mock treatment 505963.0 -199000.0 -0.42 585178.0 -185000.0 -0.42 -0.5964 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D01 compound treatment 343173.0 -362000.0 -0.77 612474.0 -158000.0 -0.36 -0.7965 -0.9398 2067624 IFLab1_003587 OC(=O)CC1(OCCO1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D02 compound treatment 1011759.0 306000.0 0.65 926771.0 157000.0 0.36 0.711 0.96 1400553 IFLab1_003588 Oc1cccc(c1)N2C(=O)C3C4CC(C=C4)C3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D03 compound treatment 1006710.0 301000.0 0.64 992797.0 223000.0 0.51 0.8096 0.9934 1107771 IFLab1_003589 CN1CCN(Cc2oc(CO)cc(=O)c2O)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D04 compound treatment 1029791.0 324000.0 0.69 1244888.0 475000.0 1.08 1.2495 0.9763 2067625 IFLab1_003590 CCCc1nnc2SCC(=Nn12)c3ccc(OC)c(OC)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D05 compound treatment 1148294.0 443000.0 0.94 910527.0 140000.0 0.32 0.8896 0.8971 1309648 IFLab1_003591 Fc1cccc(F)c1C(=O)Nc2ccc(cc2)c3nc4ccccc4[nH]3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D06 compound treatment 1266085.0 561000.0 1.19 1011229.0 241000.0 0.55 1.228 0.9382 2067626 IFLab1_003592 Cc1nnc2SCC(=Nn12)c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D07 compound treatment 1190111.0 485000.0 1.03 1083721.0 314000.0 0.71 1.2307 0.9841 1710483 IFLab1_003593 O=C(Nc1ccc2sccc2c1)c3ccc(cc3)S(=O)(=O)N4CCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D08 compound treatment 1024676.0 319000.0 0.68 1068472.0 298000.0 0.68 0.9582 1.0 2067627 IFLab1_003594 CCc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3CCCC3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D09 compound treatment 967850.0 262000.0 0.56 1074060.0 304000.0 0.69 0.882 0.9942 2067628 IFLab1_003595 OC(=O)c1sc2cc(Cl)ccc2c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D10 compound treatment 1303774.0 598000.0 1.27 1030303.0 260000.0 0.59 1.3152 0.9397 2067629 IFLab1_003596 COc1cccc2sc(=NC(=O)c3cccc(c3)C(F)(F)F)n(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D11 compound treatment 1188596.0 483000.0 1.02 885716.0 116000.0 0.26 0.9101 0.8606 2067630 IFLab1_003597 Cc1ccc(cc1)C(=O)CSc2nnc3[nH]c(=O)cc(C)n23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D12 compound treatment 1374855.0 669000.0 1.42 1160004.0 390000.0 0.89 1.6303 0.9743 1220393 IFLab1_003598 COc1ccc(Br)cc1S(=O)(=O)n2ccnc2C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D13 compound treatment 1232464.0 527000.0 1.12 1069565.0 299000.0 0.68 1.2714 0.9718 2067631 IFLab1_003599 Cc1ccc(NC2=NCCOC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D14 compound treatment 1033961.0 329000.0 0.7 1033538.0 263000.0 0.6 0.9159 0.9972 1631142 IFLab1_003600 Cc1nc2ccccc2n1CC(=O)N3CC(=O)Nc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D15 compound treatment 1078385.0 373000.0 0.79 1001738.0 232000.0 0.53 0.9314 0.9805 2067632 IFLab1_003601 O=c1ccc2ccc(OCCOc3ccc4ccc(=O)oc4c3)cc2o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D16 compound treatment 1173896.0 468000.0 0.99 995643.0 225000.0 0.51 1.0648 0.9527 1559652 IFLab1_003602 CC1CCCN(CC(O)COCc2ccc(Cl)cc2)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D17 compound treatment 1146013.0 441000.0 0.93 1082648.0 312000.0 0.71 1.1629 0.9909 2067633 IFLab1_003603 O=S(=O)(/C=C/c1ccccc1)N2CCN(Cc3ccccc3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D18 compound treatment 1178773.0 473000.0 1.0 1088628.0 318000.0 0.72 1.2216 0.9872 1444119 IFLab1_003604 Cc1cc(OCC(O)CN2CCN(CC2)c3ccccn3)ccc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D19 compound treatment 1099556.0 394000.0 0.84 869836.0 99700.0 0.23 0.7511 0.8676 1432502 IFLab1_003605 Cc1ccc(cc1)N(C2CS(=O)(=O)C=C2)C(=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D20 compound treatment 995119.0 290000.0 0.61 739627.0 -30500.0 -0.07 0.3852 0.6232 1559961 IFLab1_003606 Oc1c(ccc2cccnc12)C(N3CCCC3)c4ccc(F)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D21 compound treatment 825560.0 120000.0 0.25 814239.0 44100.0 0.1 0.251 0.9169 1239975 IFLab1_003607 CCC(=O)Oc1cccc(c1)N2C(=O)C3C4CC(C=C4)C3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D22 compound treatment 913854.0 208000.0 0.44 819069.0 48900.0 0.11 0.3911 0.8583 1400810 IFLab1_003608 O=S(=O)(N1CCc2ccccc12)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D23 mock treatment 882884.0 177000.0 0.38 698596.0 -71600.0 -0.16 0.151 0.3684 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 D24 mock treatment 510066.0 -195000.0 -0.41 516692.0 -253000.0 -0.58 -0.7003 -0.9869 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E01 compound treatment 872194.0 167000.0 0.35 830160.0 60000.0 0.14 0.3465 0.9143 1627518 IFLab1_003609 Cc1ccc(C(=O)O)c(c1)C(=O)Nc2nccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E02 compound treatment 1001157.0 296000.0 0.63 1167151.0 397000.0 0.9 1.0816 0.9841 2067634 IFLab1_003610 FC(F)(F)c1ccc2sc(CC#N)nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E03 compound treatment 1029186.0 324000.0 0.69 1145289.0 375000.0 0.85 1.0884 0.9942 1530960 IFLab1_003611 COc1ccc2cc(ccc2c1)S(=O)(=O)n3nnc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E04 compound treatment 1181593.0 476000.0 1.01 1225183.0 455000.0 1.03 1.4453 0.9999 1083304 IFLab1_003612 O=S1(=O)CC(SC#N)C=C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E05 compound treatment 1005032.0 300000.0 0.64 1193068.0 423000.0 0.96 1.129 0.9797 1193288 IFLab1_003613 COc1ccc(C)cc1S(=O)(=O)N2CCN(CC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E06 compound treatment 977163.0 272000.0 0.58 1284633.0 514000.0 1.17 1.2345 0.9468 1737734 IFLab1_003614 CCOc1cccc2cc(C(=O)N)c(=Nc3ccc(F)cc3)oc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E07 compound treatment 1031002.0 326000.0 0.69 1325526.0 555000.0 1.26 1.3809 0.9596 1655301 IFLab1_003615 COC(=O)c1sc(cc1NC(=O)C)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E08 compound treatment 1073194.0 368000.0 0.78 1280633.0 510000.0 1.16 1.372 0.9813 1496658 IFLab1_003616 Cc1nc(cs1)c2cccc(NC(=O)c3cc4ccccc4oc3=O)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E09 compound treatment 989466.0 284000.0 0.6 1108503.0 338000.0 0.77 0.9698 0.9927 2067635 IFLab1_003617 C=CCn1c(nc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E10 compound treatment 1455617.0 750000.0 1.59 1191211.0 421000.0 0.96 1.8015 0.9705 1221120 IFLab1_003618 COC(=O)c1sc2ccccc2c1NC(=O)C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E11 compound treatment 1374309.0 669000.0 1.42 1315603.0 545000.0 1.24 1.8796 0.9978 1553473 IFLab1_003619 CCc1cccc(CC)c1N(COC)C(=O)CSc2nc3ccccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E12 compound treatment 1610578.0 905000.0 1.92 1406516.0 636000.0 1.45 2.3799 0.9903 2067636 IFLab1_003620 O=C(Cn1nnc(n1)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E13 compound treatment 1559066.0 854000.0 1.81 1051377.0 281000.0 0.64 1.7318 0.9023 2067637 IFLab1_003621 O=C1C(CCc2ccccc12)Sc3nnc(o3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E14 compound treatment 908145.0 203000.0 0.43 1265628.0 495000.0 1.13 1.1004 0.9127 2067638 IFLab1_003622 CC(C)c1ccc(/C=C/2\C(=O)Nc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E15 compound treatment 1088483.0 383000.0 0.81 1206510.0 436000.0 0.99 1.2757 0.9951 2067639 IFLab1_003623 C/C(=C(/C#N)\c1nnc2CCCCCn12)/O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E16 compound treatment 928353.0 223000.0 0.47 1086244.0 316000.0 0.72 0.8424 0.9793 2067640 IFLab1_003624 CC1CSC(=N1)Nc2cccc(c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E17 compound treatment 1089305.0 384000.0 0.81 1274726.0 505000.0 1.15 1.3866 0.9859 2067641 IFLab1_003625 Cc1n[n+](CC(=O)c2ccc(Br)cc2)c(N)n1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E18 compound treatment 1182484.0 477000.0 1.01 1192636.0 422000.0 0.96 1.3943 0.9997 2067642 IFLab1_003626 O=C(Oc1ccccc1)Oc2cccc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E19 compound treatment 1057450.0 352000.0 0.75 1097598.0 327000.0 0.74 1.0541 1.0 1149978 IFLab1_003627 OC(=O)c1ccc(CNC2CCS(=O)(=O)C2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E20 compound treatment 908029.0 203000.0 0.43 1025857.0 256000.0 0.58 0.7148 0.9889 2067643 IFLab1_003628 CN(C)S(=O)(=O)c1c(C)cc(C)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E21 compound treatment 1022660.0 317000.0 0.67 1005966.0 236000.0 0.54 0.8547 0.9937 1420932 IFLab1_003629 NS(=O)(=O)c1ccc(NC(=O)COc2cccc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E22 compound treatment 768056.0 62600.0 0.13 951959.0 182000.0 0.41 0.3862 0.8895 1403291 IFLab1_003630 COC(=O)c1c(C)oc2ccc(NS(=O)(=O)c3ccc(C)cc3)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E23 mock treatment 812232.0 107000.0 0.23 830776.0 60600.0 0.14 0.2576 0.9717 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 E24 mock treatment 510338.0 -195000.0 -0.41 642419.0 -128000.0 -0.29 -0.4978 -0.985 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F01 compound treatment 926406.0 221000.0 0.47 945022.0 175000.0 0.4 0.6124 0.9967 2067644 IFLab1_003631 C1CN=C(Nc2ccccc2)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F02 compound treatment 1058241.0 353000.0 0.75 1205319.0 435000.0 0.99 1.2285 0.9905 1431348 IFLab1_003632 Oc1ccc(cc1)N2C(=O)C3C4CC(C=C4)C3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F03 compound treatment 1116763.0 411000.0 0.87 1206829.0 437000.0 0.99 1.3186 0.9979 1512484 IFLab1_003633 OC(=O)c1ccc(cc1)n2c(cc3C(=O)CCCc32)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F04 compound treatment 1117082.0 412000.0 0.87 1157079.0 387000.0 0.88 1.2391 1.0 1486736 IFLab1_003634 Cc1ccc(NC(=O)CSc2nnc3CCCCCn23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F05 compound treatment 1052510.0 347000.0 0.74 1114796.0 345000.0 0.78 1.0744 0.9995 2067645 IFLab1_003635 O=C(Nc1ccc(cc1)c2nc3ccccc3o2)/C=C/c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F06 compound treatment 1299193.0 594000.0 1.26 1282621.0 512000.0 1.17 1.714 0.9993 2067646 IFLab1_003636 Clc1ccc(cc1)C(=O)CSc2nnc3CCCCCn23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F07 compound treatment 1167212.0 462000.0 0.98 1362583.0 592000.0 1.35 1.6447 0.9877 1637291 IFLab1_003637 O=C(CCc1ccccc1)Nc2ccc3sccc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F08 compound treatment 1067772.0 362000.0 0.77 1441436.0 671000.0 1.53 1.6224 0.9495 1502473 IFLab1_003638 NC(=O)c1oc2ccccc2c1NC(=O)C3CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F09 compound treatment 1055128.0 350000.0 0.74 1415480.0 645000.0 1.47 1.5617 0.95 1560840 IFLab1_003639 O=S(=O)(N1CCc2ccccc2C1)c3cccc4cccnc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F10 compound treatment 1192685.0 487000.0 1.03 1564878.0 795000.0 1.81 2.0081 0.9648 1179572 IFLab1_003640 COc1cccc2sc(=NC(=O)C3CCCCC3)n(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F11 compound treatment 1330550.0 625000.0 1.33 1402925.0 633000.0 1.44 1.9544 0.9992 2067647 IFLab1_003641 Nc1ccc(cc1)S(=O)(=O)/N=C/2\CCCCCN2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F12 compound treatment 1616128.0 911000.0 1.93 1582453.0 812000.0 1.85 2.6711 0.9998 1682798 IFLab1_003642 Cc1c(Cl)ccc(c1Cl)S(=O)(=O)Nc2ccncc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F13 compound treatment 1544362.0 839000.0 1.78 1765809.0 996000.0 2.26 2.8583 0.9929 1211371 IFLab1_003643 CCOC(=O)c1c(C)oc2cc(Br)c(O)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F14 compound treatment 1586292.0 881000.0 1.87 1665637.0 895000.0 2.04 2.7601 0.9991 1205440 IFLab1_003644 COc1cccc(OCC(O)CN2CCCCC2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F15 compound treatment 1326105.0 621000.0 1.32 1209588.0 439000.0 1.0 1.6369 0.9908 1298587 IFLab1_003645 CC(C)(C)c1ccc(cc1)C(=O)N2CCCCCC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F16 compound treatment 1230908.0 525000.0 1.11 1169189.0 399000.0 0.91 1.4292 0.9948 1699254 IFLab1_003646 OCCN1CCN(CC(O)COCc2ccc(Cl)cc2)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F17 compound treatment 1548578.0 843000.0 1.79 1375986.0 606000.0 1.38 2.2379 0.9917 2067648 IFLab1_003647 O=C/1N(C(=S)S\C1=C/c2cccnc2)c3ccc4OCCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F18 compound treatment 1161898.0 456000.0 0.97 1195488.0 425000.0 0.97 1.3681 1.0 1181961 IFLab1_003648 COc1cccc(OC)c1OCC(O)CN2CCN(C)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F19 compound treatment 995180.0 290000.0 0.61 1061278.0 291000.0 0.66 0.9024 0.9993 1705677 IFLab1_003649 CC(C)c1ccc(OCC(C)NC(=O)c2ccc(Br)o2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F20 compound treatment 813630.0 108000.0 0.23 802966.0 32800.0 0.07 0.215 0.8911 1667146 IFLab1_003650 Oc1c(ccc2cccnc12)C(Nc3ccc(F)cc3)c4ccncc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F21 compound treatment 1054821.0 349000.0 0.74 1043231.0 273000.0 0.62 0.9628 0.9961 1613489 IFLab1_003651 CCC(=O)Oc1ccc(cc1)N2C(=O)C3C4CC(C=C4)C3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F22 compound treatment 884918.0 180000.0 0.38 1019897.0 250000.0 0.57 0.6706 0.9811 1705192 IFLab1_003652 Clc1ccc(cc1)C2CC(=O)n3c(S2)nc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F23 mock treatment 867674.0 162000.0 0.34 922171.0 152000.0 0.35 0.4876 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 F24 mock treatment 548642.0 -157000.0 -0.33 874492.0 104000.0 0.24 -0.0673 -0.1647 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G01 compound treatment 982800.0 277000.0 0.59 1113256.0 343000.0 0.78 0.9674 0.9903 2067649 IFLab1_003653 Cc1cc(C)c(C(=O)NCCCN2CCOCC2)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G02 compound treatment 1010927.0 306000.0 0.65 1327250.0 557000.0 1.27 1.3536 0.9515 2067650 IFLab1_003654 CCn1c2ccccc2c3nc4ccccc4nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G03 compound treatment 925104.0 220000.0 0.47 1316503.0 546000.0 1.24 1.2077 0.9103 1341016 IFLab1_003655 COc1ccc(I)cc1S(=O)(=O)NCc2ccccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G04 compound treatment 937468.0 232000.0 0.49 1318650.0 548000.0 1.25 1.2296 0.9173 1086344 IFLab1_003656 C=CS(=O)(=O)Cc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G05 compound treatment 1053515.0 348000.0 0.74 1418580.0 648000.0 1.47 1.5643 0.9488 1480776 IFLab1_003657 COc1ccc(C)cc1S(=O)(=O)n2nnc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G06 compound treatment 1220387.0 515000.0 1.09 1471313.0 701000.0 1.59 1.8992 0.983 2067651 IFLab1_003658 FC(F)(F)c1cccc(Nc2nnc(s2)c3cc4ccccc4oc3=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G07 compound treatment 1238079.0 533000.0 1.13 1538372.0 768000.0 1.75 2.0335 0.9777 1271620 IFLab1_003659 COC(=O)c1sc(cc1NC(=O)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G08 compound treatment 1150967.0 446000.0 0.94 1477308.0 707000.0 1.61 1.8048 0.9679 2067652 IFLab1_003660 Cc1nc(cs1)c2ccc(/N=C/c3cc(Br)ccc3O)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G09 compound treatment 970680.0 265000.0 0.56 1347724.0 578000.0 1.31 1.3262 0.9284 2067653 IFLab1_003661 C=CCn1c(Cc2ccccc2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G10 compound treatment 1481641.0 776000.0 1.65 1392358.0 622000.0 1.41 2.1639 0.9972 1416878 IFLab1_003662 COC(=O)c1sc2ccccc2c1NC(=O)COc3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G11 compound treatment 1114976.0 410000.0 0.87 1757326.0 987000.0 2.24 2.201 0.9146 1590989 IFLab1_003663 CCc1cccc(CC)c1N(COC)C(=O)Cn2c(nc3ccccc23)C(C)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G12 compound treatment 1344518.0 639000.0 1.35 1405682.0 636000.0 1.44 1.9797 0.9995 1503144 IFLab1_003664 CC(=O)n1c(N)nc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G13 compound treatment 962088.0 257000.0 0.54 1938160.0 1170000.0 2.66 2.2625 0.8347 2067654 IFLab1_003665 CC(C)N(C(=O)CSc1nnc(o1)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G14 compound treatment 1422401.0 717000.0 1.52 1727608.0 957000.0 2.18 2.614 0.9846 2067655 IFLab1_003666 Brc1cccc(c1)c2nnc(Nc3ccccc3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G15 compound treatment 1572380.0 867000.0 1.84 1623827.0 854000.0 1.94 2.672 0.9996 2067656 IFLab1_003667 Cc1cc(NC(=O)CCN2C(=O)/C(=C\c3ccccc3F)/SC2=S)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G16 compound treatment 1269899.0 564000.0 1.2 1321757.0 552000.0 1.25 1.733 0.9997 1547461 IFLab1_003668 CC(C)c1ccc(cc1)S(=O)(=O)Nc2ccc(O)c(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G17 compound treatment 1192015.0 487000.0 1.03 1491534.0 721000.0 1.64 1.8892 0.975 2067657 IFLab1_003669 N#CCc1ncc(CSc2nnnn2c3ccccc3)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G18 compound treatment 1310194.0 605000.0 1.28 1341224.0 571000.0 1.3 1.8247 1.0 1007899 IFLab1_003670 O=C(Oc1ccc2ccccc2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G19 compound treatment 1340685.0 635000.0 1.35 1175431.0 405000.0 0.92 1.6038 0.9829 1476561 IFLab1_003671 CN1CCN(CC1)C(=O)COc2ccc(Oc3ccccc3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G20 compound treatment 1129383.0 424000.0 0.9 1420934.0 651000.0 1.48 1.6818 0.9715 1376608 IFLab1_003672 OCCNS(=O)(=O)c1ccc2NC(=O)c3cccc1c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G21 compound treatment 968318.0 263000.0 0.56 993161.0 223000.0 0.51 0.7526 0.9989 1532797 IFLab1_003673 CCOC(=O)Cc1csc(NC(=O)COc2cccc3ccccc23)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G22 compound treatment 1059070.0 354000.0 0.75 1302062.0 532000.0 1.21 1.3853 0.9736 1730280 IFLab1_003674 O=C(Oc1ccccc1)Oc2ccc3ccc(=O)oc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G23 mock treatment 781311.0 75900.0 0.16 965382.0 195000.0 0.44 0.4276 0.9058 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 G24 mock treatment 611846.0 -93600.0 -0.2 859099.0 88900.0 0.2 0.0027 0.0097 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H01 compound treatment 570785.0 -135000.0 -0.29 721239.0 -48900.0 -0.11 -0.2804 -0.9156 1666173 IFLab1_003675 O=C1C(CN2CCCCC2)CCCC1CN3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H02 compound treatment 1049053.0 344000.0 0.73 1372785.0 603000.0 1.37 1.4839 0.9563 1172015 IFLab1_003676 CC1=CCC2C(C1)C(=O)N(C2=O)c3ccc(O)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H03 compound treatment 1138054.0 433000.0 0.92 1359569.0 589000.0 1.34 1.5961 0.9829 2067658 IFLab1_003677 Clc1ccc(cc1)C2C=C(Nc3ncnn23)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H04 compound treatment 1535425.0 830000.0 1.76 1443150.0 673000.0 1.53 2.3262 0.9976 1328685 IFLab1_003678 COc1ccc(NC(=O)CSc2nnc3CCCCCn23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H05 compound treatment 1262552.0 557000.0 1.18 1199983.0 430000.0 0.98 1.5262 0.9956 2067659 IFLab1_003679 COC(=O)c1sc2ccccc2c1NC(=O)c3ccc(Br)s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H06 compound treatment 1585416.0 880000.0 1.87 1475502.0 705000.0 1.6 2.4531 0.9972 1111757 IFLab1_003680 Fc1ccc(cc1)c2nc3ccccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H07 compound treatment 1375089.0 670000.0 1.42 1538406.0 768000.0 1.75 2.2389 0.9947 1734773 IFLab1_003681 O=C(CN1C(=O)CCC1=O)Nc2ccc3sccc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H08 compound treatment 1194538.0 489000.0 1.04 1332755.0 563000.0 1.28 1.6377 0.9946 1304791 IFLab1_003682 COc1cccc2sc(=NC(=O)c3cccc4ccccc34)n(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H09 compound treatment 1734625.0 1030000.0 2.18 1448480.0 678000.0 1.54 2.6333 0.9856 1621309 IFLab1_003683 Cc1ccccc1NC(=O)CSc2ccccc2C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H10 compound treatment 1495942.0 791000.0 1.68 1587642.0 817000.0 1.86 2.4993 0.9987 1634225 IFLab1_003684 Cc1ccc(cc1C)C(=O)Nc2c(oc3ccccc23)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H11 compound treatment 1705944.0 1000000.0 2.12 1370647.0 600000.0 1.37 2.4652 0.9773 2067660 IFLab1_003685 Cc1ccccc1NC(=O)CSC2=NCCN2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H12 compound treatment 1739166.0 1030000.0 2.19 1888408.0 1120000.0 2.54 3.3474 0.9973 1650383 IFLab1_003686 CCC1CCCCN1S(=O)(=O)c2ccc3cc(OC)ccc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H13 compound treatment 1922766.0 1220000.0 2.58 1777224.0 1010000.0 2.29 3.4439 0.9982 1536420 IFLab1_003687 CCOC(=O)c1c(C)oc2cc(Br)c(OCC#N)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H14 compound treatment 1393315.0 688000.0 1.46 2425054.0 1650000.0 3.76 3.6917 0.9149 1634405 IFLab1_003688 COc1cccc(OCC(O)CN2CC(C)CC(C)C2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H15 compound treatment 1824635.0 1120000.0 2.37 1899201.0 1130000.0 2.57 3.4929 0.9992 2067661 IFLab1_003689 COC(=O)c1c(NC(=O)CCNCc2ccco2)sc3CCCc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H16 compound treatment 1435766.0 730000.0 1.55 1745453.0 975000.0 2.22 2.6628 0.9846 1404662 IFLab1_003690 CCOC(=O)C1CCN(CC(O)COCc2ccc(Cl)cc2)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H17 compound treatment 1294765.0 589000.0 1.25 1148537.0 378000.0 0.86 1.4918 0.9834 2067662 IFLab1_003691 Cc1sc2ncnc(SCC(=O)c3ccc4OCCOc4c3)c2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H18 compound treatment 1708916.0 1000000.0 2.13 1216145.0 446000.0 1.01 2.2213 0.9425 1544274 IFLab1_003692 CC1CCCCN1CC(O)COc2ccc3ccccc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H19 compound treatment 1471688.0 766000.0 1.62 1121413.0 351000.0 0.8 1.7134 0.9465 1291788 IFLab1_003693 CC(C)(C)c1csc(NC(=O)c2ccc(Br)o2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H20 compound treatment 1040180.0 335000.0 0.71 1149723.0 380000.0 0.86 1.112 0.9953 1455013 IFLab1_003694 CC1(C)CC(CC(C)(C)N1)NC(=O)c2cc3ccccc3oc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H21 compound treatment 1037716.0 332000.0 0.7 1094196.0 324000.0 0.74 1.0191 0.9997 2067663 IFLab1_003695 COC(=O)c1ccc(cc1)N2C(=O)CCC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H22 compound treatment 1057173.0 352000.0 0.75 1134070.0 364000.0 0.83 1.1123 0.9987 1158912 IFLab1_003696 COc1ccc(cc1)C2CC(=O)n3c(S2)nc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H23 mock treatment 914026.0 209000.0 0.44 1100309.0 330000.0 0.75 0.8435 0.9682 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 H24 mock treatment 636916.0 -68500.0 -0.15 908835.0 139000.0 0.32 0.1203 0.3465 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I01 compound treatment 837859.0 132000.0 0.28 705211.0 -64900.0 -0.15 0.0941 0.2968 2067664 IFLab1_003697 CC(C)c1cc(C(C)C)c(S(=O)NCCCN2CCOCC2)c(c1)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I02 compound treatment 932572.0 227000.0 0.48 707528.0 -62600.0 -0.14 0.2398 0.4776 2067665 IFLab1_003698 CC(C)n1c2ccccc2c3nc4ccccc4nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I03 compound treatment 1153480.0 448000.0 0.95 1394420.0 624000.0 1.42 1.6753 0.9809 1218592 IFLab1_003699 COc1ccc2cc(ccc2c1)S(=O)(=O)N3CCN(Cc4ccccc4)CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I04 compound treatment 1270122.0 565000.0 1.2 1327829.0 558000.0 1.27 1.7431 0.9996 2067666 IFLab1_003700 Brc1cccc(c1)S(=O)(=O)C=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I05 compound treatment 1149867.0 444000.0 0.94 1353620.0 583000.0 1.33 1.6043 0.986 1119800 IFLab1_003701 CCC(=O)Nc1c2CSCc2nn1c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I06 compound treatment 1624472.0 919000.0 1.95 1506750.0 737000.0 1.67 2.5619 0.9972 1216791 IFLab1_003702 C1CSC(N1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I07 compound treatment 1447817.0 742000.0 1.57 1641271.0 871000.0 1.98 2.5133 0.9935 1129857 IFLab1_003703 COC(=O)c1sc(cc1NC(=O)C2CC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I08 compound treatment 1373221.0 668000.0 1.42 1353673.0 584000.0 1.33 1.9392 0.9995 1217935 IFLab1_003704 Cc1nc(cs1)c2cccc(N)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I09 compound treatment 1448949.0 744000.0 1.58 1513532.0 743000.0 1.69 2.3097 0.9994 2067667 IFLab1_003705 CCn1c(Cc2ccccc2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I10 compound treatment 1541770.0 836000.0 1.77 1833206.0 1060000.0 2.42 2.9627 0.9884 1464364 IFLab1_003706 COC(=O)c1sc2ccccc2c1NC(=O)Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I11 compound treatment 1429219.0 724000.0 1.53 1679099.0 909000.0 2.07 2.5463 0.9893 1535035 IFLab1_003707 CC(C)N(C(=O)Cn1c(C)nc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I12 compound treatment 1578515.0 873000.0 1.85 1602296.0 832000.0 1.89 2.6466 0.9999 1073760 IFLab1_003708 COc1ccc(NC2=NCCS2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I13 compound treatment 1498051.0 793000.0 1.68 992862.0 223000.0 0.51 1.5462 0.881 2067668 IFLab1_003709 Cc1nnc(SCC(=O)Nc2ccccc2)n1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I14 compound treatment 1350406.0 645000.0 1.37 2329606.0 1560000.0 3.55 3.4739 0.9142 1344074 IFLab1_003710 CC(C)N(C(=O)Cn1c(=N)sc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I15 compound treatment 1151250.0 446000.0 0.95 1809034.0 1040000.0 2.36 2.3385 0.9192 1379574 IFLab1_003711 CCOC(=O)CSc1nc2ccccc2c(=O)n1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I16 compound treatment 1449010.0 744000.0 1.58 1916622.0 1150000.0 2.61 2.9578 0.971 2067669 IFLab1_003712 Clc1ccccc1C(=O)Oc2cccc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I17 compound treatment 1118519.0 413000.0 0.88 1474035.0 704000.0 1.6 1.7509 0.9598 1735150 IFLab1_003713 N#CCc1ncc(CSc2nc3ccccc3[nH]2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I18 compound treatment 1270326.0 565000.0 1.2 1346519.0 576000.0 1.31 1.7734 0.999 1013810 IFLab1_003714 O=C1OC2(CCCCC2)OC1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I19 compound treatment 1002415.0 297000.0 0.63 1288612.0 518000.0 1.18 1.2787 0.9569 1228915 IFLab1_003715 COc1cccc(OCC(=O)Nc2ccc(F)cc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I20 compound treatment 1065549.0 360000.0 0.76 1292517.0 522000.0 1.19 1.3796 0.9772 1248295 IFLab1_003716 CN(C)S(=O)(=O)c1ccc2NC(=O)c3cccc1c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I21 compound treatment 1070502.0 365000.0 0.77 1300885.0 531000.0 1.21 1.4005 0.977 1296632 IFLab1_003717 OC(=O)CNC(=O)COc1cccc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I22 compound treatment 1175808.0 470000.0 1.0 1229180.0 459000.0 1.04 1.4431 0.9997 2067670 IFLab1_003718 CN1CCN(CC1)c2cc(C)ncn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I23 mock treatment 945741.0 240000.0 0.51 1157831.0 388000.0 0.88 0.9835 0.9661 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 I24 mock treatment 953766.0 248000.0 0.53 879885.0 110000.0 0.25 0.5487 0.9418 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J01 compound treatment 762006.0 56600.0 0.12 852158.0 82000.0 0.19 0.2167 0.9773 1357445 IFLab1_003719 CC1(C)COC(=O)C1OC(=O)c2ccccc2C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J02 compound treatment 1092022.0 387000.0 0.82 1358333.0 588000.0 1.34 1.5251 0.9724 2067671 IFLab1_003720 CC(=C)C(=O)Oc1ccc(cc1)N2Cc3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J03 compound treatment 969489.0 264000.0 0.56 1524990.0 755000.0 1.72 1.6094 0.8915 1673475 IFLab1_003721 CCc1nc(c2ccccc2)c3ccccn13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J04 compound treatment 1116578.0 411000.0 0.87 1355868.0 586000.0 1.33 1.558 0.9789 2067672 IFLab1_003722 CCc1nnc2SCC(=Nn12)c3ccc4OCCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J05 compound treatment 1208695.0 503000.0 1.07 1174289.0 404000.0 0.92 1.4041 0.9972 2067673 IFLab1_003723 COC(=O)c1sc2ccccc2c1NC(=O)c3cc(Cl)sc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J06 compound treatment 945419.0 240000.0 0.51 912855.0 143000.0 0.32 0.5892 0.9764 2067674 IFLab1_003724 Fc1ccc(NC2=NC(=O)/C(=C\c3ccc4OCOc4c3)/S2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J07 compound treatment 1325041.0 620000.0 1.31 1391787.0 622000.0 1.41 1.9282 0.9993 1605554 IFLab1_003725 O=C(Nc1ccc2sccc2c1)c3cccc(c3)N4C(=O)CCC4=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J08 compound treatment 1465206.0 760000.0 1.61 1315905.0 546000.0 1.24 2.0163 0.9917 1647947 IFLab1_003726 COc1cccc2sc(=NC(=O)c3ccc(C#N)cc3)n(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J09 compound treatment 1391090.0 686000.0 1.45 1335659.0 566000.0 1.29 1.937 0.9981 2067675 IFLab1_003727 OC(=O)c1ccccc1SCC(=O)Nc2cccc(c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J10 compound treatment 1267294.0 562000.0 1.19 1511150.0 741000.0 1.68 2.0335 0.9856 1316524 IFLab1_003728 COC(=O)c1ccc(cc1)C(=O)N=c2sc3cc(F)ccc3n2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J11 compound treatment 1168338.0 463000.0 0.98 1673952.0 904000.0 2.05 2.1469 0.9428 2067676 IFLab1_003729 COc1ccc(NC(=O)CSC2=NCCN2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J12 compound treatment 1389226.0 684000.0 1.45 1764267.0 994000.0 2.26 2.6232 0.977 1447150 IFLab1_003730 COc1cc(C)c(cc1S(=O)(=O)N2CCCC(C)C2)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J13 compound treatment 1432949.0 728000.0 1.54 1366804.0 597000.0 1.36 2.0498 0.998 2067677 IFLab1_003731 COc1ccc(/C=C/C(=O)Nc2sc3CCCCc3c2C(=O)N)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J14 compound treatment 1272088.0 567000.0 1.2 1506803.0 737000.0 1.67 2.0337 0.9867 1637379 IFLab1_003732 CCN1CCN(CC(O)COc2cccc(OC)c2)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J15 compound treatment 1534551.0 829000.0 1.76 1487174.0 717000.0 1.63 2.3956 0.9993 2067678 IFLab1_003733 Cc1ccc(/C=C\2/SC(=S)N(C2=O)c3ccc(cc3)S(=O)(=O)N)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J16 compound treatment 1468348.0 763000.0 1.62 1465501.0 695000.0 1.58 2.2615 0.9999 1303213 IFLab1_003734 CN1CCN(CC(O)COc2ccc(cc2)C3CCCCC3)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J17 compound treatment 1523813.0 818000.0 1.73 1423707.0 654000.0 1.49 2.2775 0.997 1246133 IFLab1_003735 CCC(CO)Nc1nc(C)nc2sc3CCCc3c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J18 compound treatment 1057046.0 352000.0 0.75 1398219.0 628000.0 1.43 1.5368 0.9541 1283409 IFLab1_003736 CC1CCCCN1CC(O)COc2c(F)cc(Br)cc2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J19 compound treatment 1181203.0 476000.0 1.01 1179748.0 410000.0 0.93 1.3717 0.9992 1562712 IFLab1_003737 O=C1C2C3CC(C=C3)C2C(=O)N1c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J20 compound treatment 1150179.0 445000.0 0.94 1137911.0 368000.0 0.84 1.2579 0.9982 2067679 IFLab1_003738 O=C/1Oc2ccccc2C(=O)\C1=C\NN3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J21 compound treatment 1070544.0 365000.0 0.77 1136850.0 367000.0 0.83 1.1369 0.9993 1327796 IFLab1_003739 OC(=O)CCCN1C(=O)C2C3CC(C=C3)C2C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J22 compound treatment 975583.0 270000.0 0.57 1159124.0 389000.0 0.88 1.0303 0.9779 1421681 IFLab1_003740 OC(=O)C1CCN(CC1)S(=O)(=O)c2cccc3cccnc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J23 mock treatment 874230.0 169000.0 0.36 1055534.0 285000.0 0.65 0.7119 0.9607 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 J24 mock treatment 598164.0 -107000.0 -0.23 856748.0 86600.0 0.2 -0.0216 -0.0717 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K01 compound treatment 559437.0 -146000.0 -0.31 616897.0 -153000.0 -0.35 -0.4652 -0.9983 1597075 IFLab1_003741 Cc1ccc(c(C)c1)S(=O)(=O)n2cnc3cc(C)c(C)cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K02 compound treatment 1106006.0 401000.0 0.85 1225370.0 455000.0 1.03 1.3323 0.9952 2067680 IFLab1_003742 CCCn1c2ccccc2c3nc4ccccc4nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K03 compound treatment 1119475.0 414000.0 0.88 1197263.0 427000.0 0.97 1.3073 0.9987 2067681 IFLab1_003743 Clc1ccc2n(nnc2c1)C(=O)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K04 compound treatment 914540.0 209000.0 0.44 1086581.0 316000.0 0.72 0.8222 0.973 1643138 IFLab1_003744 O=S1(=O)CCC(C1)NC(=S)SCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K05 compound treatment 1099888.0 394000.0 0.84 995740.0 226000.0 0.51 0.954 0.9725 1547490 IFLab1_003745 Cc1ccc(cc1)n2nc3CSCc3c2NC(=O)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K06 compound treatment 1043744.0 338000.0 0.72 1025524.0 255000.0 0.58 0.9177 0.9945 1294431 IFLab1_003746 COc1ccc(cc1)C2SCCN2S(=O)(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K07 compound treatment 1235757.0 530000.0 1.12 1026445.0 256000.0 0.58 1.207 0.9532 1655407 IFLab1_003747 COC(=O)c1sc(cc1NC(=O)C2CCCCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K08 compound treatment 1023208.0 318000.0 0.67 1064145.0 294000.0 0.67 0.949 1.0 1583005 IFLab1_003748 COc1ccccc1C(=O)Nc2ccc(cc2)c3csc(C)n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K09 compound treatment 1099864.0 394000.0 0.84 1125532.0 355000.0 0.81 1.1626 0.9999 2067682 IFLab1_003749 CCCCn1c(nc2ccccc12)C(C)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K10 compound treatment 1064502.0 359000.0 0.76 1040103.0 270000.0 0.61 0.9723 0.9943 1479098 IFLab1_003750 O=C(Nc1ncc(s1)c2ccccc2)c3cccc(c3)N4C(=O)CCC4=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K11 compound treatment 1089378.0 384000.0 0.81 1219170.0 449000.0 1.02 1.2974 0.9937 1157513 IFLab1_003751 CC(C)N(C(=O)Cn1c(CO)nc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K12 compound treatment 1162388.0 457000.0 0.97 1387870.0 618000.0 1.4 1.6781 0.9836 2067683 IFLab1_003752 CCOc1ccc(cc1)n2nnnc2SCC(=O)c3c(C)cc(C)cc3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K13 compound treatment 1019808.0 314000.0 0.67 946448.0 176000.0 0.4 0.7547 0.9704 1467007 IFLab1_003753 Cc1cc(=O)[nH]c(SCC(=O)Nc2ccccc2C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K14 compound treatment 1031989.0 327000.0 0.69 1212296.0 442000.0 1.01 1.2004 0.9834 2067684 IFLab1_003754 COc1ccc(NC(=O)CSc2nnc(C)n2c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K15 compound treatment 1027531.0 322000.0 0.68 1261166.0 491000.0 1.12 1.2722 0.9722 1301130 IFLab1_003755 O=C(CSc1nc2ccccc2c(=O)n1c3ccccc3)N4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K16 compound treatment 1054869.0 349000.0 0.74 1050163.0 280000.0 0.64 0.974 0.9972 1621327 IFLab1_003756 OC(=O)CC(NS(=O)(=O)c1ccc(Br)cc1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K17 compound treatment 1226165.0 521000.0 1.1 1030147.0 260000.0 0.59 1.1986 0.9572 1550526 IFLab1_003757 O=C(N1CCCC1)c2ccc(cc2)S(=O)(=O)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K18 compound treatment 1012095.0 307000.0 0.65 972924.0 203000.0 0.46 0.7857 0.9858 1036303 IFLab1_003758 COc1ccc(NS(=O)(=O)c2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K19 compound treatment 890223.0 185000.0 0.39 979429.0 209000.0 0.48 0.6135 0.9953 1138357 IFLab1_003759 Cc1ccc(Oc2ccc(OCC(=O)NCC3CCCO3)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K20 compound treatment 918038.0 213000.0 0.45 923069.0 153000.0 0.35 0.5646 0.9918 1260052 IFLab1_003760 CC1CCN(CC1)S(=O)(=O)c2ccc3NC(=O)c4cccc2c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K21 compound treatment 911731.0 206000.0 0.44 896362.0 126000.0 0.29 0.5122 0.9791 1661854 IFLab1_003761 OCCSc1nc2sc3CCCCc3c2c(=O)n1c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K22 compound treatment 758058.0 52600.0 0.11 895607.0 125000.0 0.29 0.2806 0.9161 1442345 IFLab1_003762 CCn1c(SCc2nc3ccccc3[nH]2)nnc1c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K23 mock treatment 827021.0 122000.0 0.26 771822.0 1670.0 0.0 0.185 0.7174 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 K24 mock treatment 604152.0 -101000.0 -0.21 560936.0 -209000.0 -0.48 -0.4881 -0.9354 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L01 compound treatment 616446.0 -89000.0 -0.19 609828.0 -160000.0 -0.36 -0.3911 -0.953 1421062 IFLab1_003763 CCN1CCN(Cc2oc(CO)cc(=O)c2O)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L02 compound treatment 963386.0 258000.0 0.55 1113885.0 344000.0 0.78 0.9393 0.9848 1742285 IFLab1_003764 CC(=O)Oc1cccc(c1)N2Cc3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L03 compound treatment 911020.0 206000.0 0.44 1062598.0 292000.0 0.66 0.7784 0.979 1590090 IFLab1_003765 COc1cccc2cc(c3nc4ccccc4s3)c(=O)oc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L04 compound treatment 1011657.0 306000.0 0.65 1056090.0 286000.0 0.65 0.9188 1.0 2067685 IFLab1_003766 FC(F)(F)c1nnc2SCC(=Nn12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L05 compound treatment 1081165.0 376000.0 0.8 1025274.0 255000.0 0.58 0.9734 0.9879 1623297 IFLab1_003767 O=C(Nc1ccc2sccc2c1)C3CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L06 compound treatment 1032048.0 327000.0 0.69 1025336.0 255000.0 0.58 0.8999 0.9961 2067686 IFLab1_003768 Oc1ccc(/C=C\2/SC(=NC2=O)Nc3cccnc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L07 compound treatment 913699.0 208000.0 0.44 1128064.0 358000.0 0.81 0.8876 0.9587 2067687 IFLab1_003769 COC(=O)c1ccc(cc1)C(=O)Nc2ccc3sccc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L08 compound treatment 1027794.0 322000.0 0.68 959723.0 190000.0 0.43 0.788 0.9753 1691783 IFLab1_003770 NC(=O)c1oc2ccccc2c1NC(=O)Cc3cccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L09 compound treatment 1193814.0 488000.0 1.04 1029435.0 259000.0 0.59 1.149 0.9643 1429998 IFLab1_003771 Cc1ccc(cc1)C(=O)Nc2ccc(cc2)c3nnc4CCCCCn34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L10 compound treatment 1317935.0 613000.0 1.3 1040315.0 270000.0 0.61 1.3525 0.9416 1920805 IFLab1_003772 CCOC(=O)CSc1nc2ccccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L11 compound treatment 1245202.0 540000.0 1.14 1166698.0 397000.0 0.9 1.4467 0.993 1481544 IFLab1_003773 Brc1ccc(OCc2nnc3CCCCCn23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L12 compound treatment 1491041.0 786000.0 1.67 759943.0 -10200.0 -0.02 1.1613 0.6972 1230624 IFLab1_003774 CC1CN(CCN1C(=O)c2cccs2)C(=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L13 compound treatment 1248907.0 543000.0 1.15 1230256.0 460000.0 1.05 1.5544 0.9988 2067688 IFLab1_003775 Cc1noc(C)c1CSc2ncnc3sc4CCCCc4c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L14 compound treatment 1434416.0 729000.0 1.55 1109793.0 340000.0 0.77 1.6388 0.9486 1568403 IFLab1_003776 COc1cccc(OCC(O)CN2CCN(CC2)c3ccc(F)cc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L15 compound treatment 1356283.0 651000.0 1.38 1091998.0 322000.0 0.73 1.4931 0.956 2067689 IFLab1_003777 NS(=O)(=O)c1ccc(cc1)N2C(=O)/C(=C\C=C\c3ccccc3)/SC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L16 compound treatment 1240783.0 535000.0 1.13 999212.0 229000.0 0.52 1.1708 0.9376 1585215 IFLab1_003778 CCN1CCN(CC(O)COc2ccc(cc2)C3CCCCC3)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L17 compound treatment 1116768.0 411000.0 0.87 1042360.0 272000.0 0.62 1.0542 0.9859 2067690 IFLab1_003779 Cc1sc2ncnc(Sc3ccccc3)c2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L18 compound treatment 1117353.0 412000.0 0.87 581601.0 -189000.0 -0.43 0.3144 0.3232 1457194 IFLab1_003780 CC1CCCCN1CC(O)COc2cc(C)c(Cl)c(C)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L19 compound treatment 1101753.0 396000.0 0.84 994412.0 224000.0 0.51 0.9547 0.9713 1396726 IFLab1_003781 CC(C)CC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L20 compound treatment 1046197.0 341000.0 0.72 968356.0 198000.0 0.45 0.8295 0.9742 2067691 IFLab1_003782 COc1ccc(N/C=C/2\C(=O)OC(=CC2=O)C)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L21 compound treatment 989652.0 284000.0 0.6 946029.0 176000.0 0.4 0.7088 0.9802 1156241 IFLab1_003783 CC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L22 compound treatment 911658.0 206000.0 0.44 962892.0 193000.0 0.44 0.619 1.0 1271483 IFLab1_003784 Fc1ccc(cc1)N2CCN(CC2)S(=O)(=O)c3ccc4ccccc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L23 mock treatment 873553.0 168000.0 0.36 864317.0 94200.0 0.21 0.4034 0.9703 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 L24 mock treatment 667642.0 -37800.0 -0.08 714650.0 -55500.0 -0.13 -0.1458 -0.9759 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M01 compound treatment 593078.0 -112000.0 -0.24 719577.0 -50600.0 -0.11 -0.2497 -0.9442 1722879 IFLab1_003785 O=C(NCc1ccc2OCOc2c1)c3cc4ccccc4oc3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M02 compound treatment 827076.0 122000.0 0.26 1062685.0 293000.0 0.67 0.6527 0.9149 2067692 IFLab1_003786 CC(C)Cn1c2ccccc2c3nc4ccccc4nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M03 compound treatment 963878.0 258000.0 0.55 1027682.0 258000.0 0.59 0.8015 0.9995 1334268 IFLab1_003787 COc1ccc(OC)c(c1)S(=O)(=O)N2C(C)CCCC2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M04 compound treatment 912779.0 207000.0 0.44 995020.0 225000.0 0.51 0.6724 0.9972 1337692 IFLab1_003788 O=C(NC1CS(=O)(=O)C=C1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M05 compound treatment 982397.0 277000.0 0.59 951397.0 181000.0 0.41 0.7066 0.985 1555709 IFLab1_003789 Cc1cc(C)cc(c1)n2nc3CSCc3c2NC(=O)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M06 compound treatment 1259925.0 555000.0 1.18 996351.0 226000.0 0.51 1.1949 0.9312 1577333 IFLab1_003790 OCCNC(=O)c1cc2cc(Br)ccc2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M07 compound treatment 990631.0 285000.0 0.6 1070341.0 300000.0 0.68 0.9101 0.9982 1552568 IFLab1_003791 O=C(Cc1ccccc1)Nc2nc(cs2)c3nc4ccccc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M08 compound treatment 947924.0 243000.0 0.51 1101255.0 331000.0 0.75 0.8958 0.9827 1670918 IFLab1_003792 Cc1nc(sc1C(=O)Nc2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M09 compound treatment 1044815.0 339000.0 0.72 1088205.0 318000.0 0.72 1.0201 1.0 1030469 IFLab1_003793 CC(O)c1nc2ccccc2n1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M10 compound treatment 1045525.0 340000.0 0.72 1141694.0 372000.0 0.84 1.1071 0.9969 1299003 IFLab1_003794 CCC(=O)Nc1cccc(c1)c2nc3ccccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M11 compound treatment 1082410.0 377000.0 0.8 1093529.0 323000.0 0.74 1.085 0.9991 1699317 IFLab1_003795 CC(C)N(C(=O)Cn1c(nc2ccccc12)C(C)O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M12 compound treatment 993147.0 288000.0 0.61 1301609.0 531000.0 1.21 1.2857 0.9499 1504395 IFLab1_003796 CC(C)N(C(=O)CSc1nc2ccccc2[nH]1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M13 compound treatment 1137626.0 432000.0 0.92 1171446.0 401000.0 0.91 1.293 1.0 2067693 IFLab1_003797 CCOc1ccc(cc1)C(=O)CSc2nnc(CC)n2N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M14 compound treatment 1109614.0 404000.0 0.86 1145544.0 375000.0 0.85 1.2094 1.0 2067694 IFLab1_003798 c1csc(c1)c2cn3ccsc3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M15 compound treatment 1160147.0 455000.0 0.96 1275295.0 505000.0 1.15 1.4938 0.9962 1406732 IFLab1_003799 OC(=O)c1ccc(CSc2nc3ccccc3s2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M16 compound treatment 1002910.0 297000.0 0.63 1031326.0 261000.0 0.59 0.8658 0.9995 1032066 IFLab1_003800 Cc1ccccc1NS(=O)(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M17 compound treatment 1119782.0 414000.0 0.88 1089498.0 319000.0 0.73 1.1345 0.9955 2067695 IFLab1_003801 Cc1ccc(cc1)C(=O)CSc2nnnn2c3cccc(C)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M18 compound treatment 1101642.0 396000.0 0.84 1168335.0 398000.0 0.91 1.2341 0.9993 1463364 IFLab1_003802 CCOc1ccc(cc1)S(=O)(=O)N2CCC(C)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M19 compound treatment 859070.0 154000.0 0.33 1108160.0 338000.0 0.77 0.7737 0.927 1369379 IFLab1_003803 CC1CCCC(C)N1C(=O)COc2ccc(Br)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M20 compound treatment 886378.0 181000.0 0.38 986923.0 217000.0 0.49 0.6198 0.9923 1641505 IFLab1_003804 CCOc1ccc(cc1)S(=O)(=O)Nc2cc(Cl)c(O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M21 compound treatment 986670.0 281000.0 0.6 974319.0 204000.0 0.46 0.7498 0.9923 2067696 IFLab1_003805 CN(C)c1nc(c2ccccc2)c3cc(Cl)ccc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M22 compound treatment 912506.0 207000.0 0.44 981643.0 211000.0 0.48 0.6504 0.999 2067697 IFLab1_003806 COC(=O)CN1CCN(CC1)S(=O)(=O)c2ccc(Br)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M23 mock treatment 850715.0 145000.0 0.31 859873.0 89700.0 0.2 0.3621 0.98 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 M24 mock treatment 695863.0 -9550.0 -0.02 647064.0 -123000.0 -0.28 -0.2122 -0.7563 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N01 compound treatment 653165.0 -52200.0 -0.11 623214.0 -147000.0 -0.33 -0.3145 -0.8937 1262773 IFLab1_003807 OC(c1ccc2OCOc2c1)c3nccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N02 compound treatment 1001251.0 296000.0 0.63 990288.0 220000.0 0.5 0.7974 0.9938 2067698 IFLab1_003808 COC(=O)c1ccc(NC(=O)CSC2=NCCN2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N03 compound treatment 1107664.0 402000.0 0.85 1094419.0 324000.0 0.74 1.1243 0.9974 1162882 IFLab1_003809 Cc1[nH]c2ccccc2c1C(N3CCOCC3)c4ccncc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N04 compound treatment 1139433.0 434000.0 0.92 1148663.0 379000.0 0.86 1.2591 0.9994 1283766 IFLab1_003810 Cc1n[nH]c(O)c1C2=NCCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N05 compound treatment 1060074.0 355000.0 0.75 966246.0 196000.0 0.45 0.8469 0.9689 2067699 IFLab1_003811 O=C(Nc1ccc2sccc2c1)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N06 compound treatment 1245203.0 540000.0 1.14 1101028.0 331000.0 0.75 1.3411 0.9793 2067700 IFLab1_003812 COC(=O)c1ccc(/C=C\2/SC(=NC2=O)Nc3cccnc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N07 compound treatment 1011314.0 306000.0 0.65 956788.0 187000.0 0.42 0.7586 0.9789 1237264 IFLab1_003813 CSc1nc2ccc3nc(N)sc3c2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N08 compound treatment 1096971.0 392000.0 0.83 1089356.0 319000.0 0.73 1.1001 0.9978 1137905 IFLab1_003814 Cc1ccc2n(C)c(=NC(=O)Cc3cccc4ccccc34)sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N09 compound treatment 1149974.0 445000.0 0.94 1112840.0 343000.0 0.78 1.2173 0.9955 1632673 IFLab1_003815 CC(=O)Nc1ccc(cc1)c2nnc3CCCCCn23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N10 compound treatment 1142442.0 437000.0 0.93 1150067.0 380000.0 0.86 1.2659 0.9994 2067701 IFLab1_003816 Cc1ccc(N/C=C(\C#N)/c2nc(cs2)c3cc4ccccc4oc3=O)cc1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N11 compound treatment 1209526.0 504000.0 1.07 1151745.0 382000.0 0.87 1.3691 0.9946 1475279 IFLab1_003817 CCc1ccc(cc1)C(=O)CSc2ccccc2C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N12 compound treatment 1042584.0 337000.0 0.71 1125685.0 356000.0 0.81 1.077 0.9981 1242387 IFLab1_003818 Cc1cccc(c1)C(=O)N2CCCN(CC2)C(=O)c3cccc(C)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N13 compound treatment 1074523.0 369000.0 0.78 1222589.0 452000.0 1.03 1.2807 0.9909 2067702 IFLab1_003819 Cc1sc2ncnc(Sc3nnnn3c4ccccc4)c2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N14 compound treatment 1053333.0 348000.0 0.74 1169380.0 399000.0 0.91 1.1634 0.9947 1370244 IFLab1_003820 COc1cccc(OCC(O)CN2CCc3ccccc3C2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N15 compound treatment 1086539.0 381000.0 0.81 1130418.0 360000.0 0.82 1.1505 1.0 2067703 IFLab1_003821 OC(=O)COc1ccccc1/C=C\2/SC(=S)N(C2=O)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N16 compound treatment 1090474.0 385000.0 0.82 1129269.0 359000.0 0.82 1.1546 1.0 1541183 IFLab1_003822 CC1CN(CC(O)COc2ccc(cc2)C3CCCCC3)CC(C)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N17 compound treatment 1177010.0 472000.0 1.0 1097014.0 327000.0 0.74 1.2324 0.9893 1214816 IFLab1_003823 NC(=O)CCS(=O)(=O)CCN1CCCCC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N18 compound treatment 1053820.0 348000.0 0.74 405705.0 -364000.0 -0.83 -0.0636 -0.0573 1663477 IFLab1_003824 Oc1ccccc1C(Nc2nccs2)c3ccc4cccnc4c3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N19 compound treatment 1119864.0 414000.0 0.88 1026032.0 256000.0 0.58 1.0326 0.98 2067704 IFLab1_003825 O=C1C2C3CC(C=C3)C2C(=O)N1c4ccccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N20 compound treatment 1109738.0 404000.0 0.86 1004908.0 235000.0 0.53 0.9835 0.974 2067705 IFLab1_003826 Clc1ccc(SCc2cn3cccnc3n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N21 compound treatment 1020688.0 315000.0 0.67 1013024.0 243000.0 0.55 0.8631 0.9955 1043174 IFLab1_003827 O=C1C2C3CC(C=C3)C2C(=O)N1c4nccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N22 compound treatment 991337.0 286000.0 0.61 934957.0 165000.0 0.37 0.6936 0.9733 2067706 IFLab1_003828 CC1CCN(CC1)S(=O)(=O)c2ccc(/C=C/C(=O)O)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N23 mock treatment 801145.0 95700.0 0.2 921118.0 151000.0 0.34 0.3862 0.9686 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 N24 mock treatment 595044.0 -110000.0 -0.23 676666.0 -93500.0 -0.21 -0.3157 -0.9988 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O01 compound treatment 595739.0 -110000.0 -0.23 501110.0 -269000.0 -0.61 -0.5969 -0.9122 1377919 IFLab1_003829 COc1ccc(Cl)cc1S(=O)(=O)N2CCCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O02 compound treatment 1032922.0 328000.0 0.69 1088366.0 318000.0 0.72 1.0025 0.9998 2899 IFLab1_003830 COc1ccc(cc1)c2noc(CC(=O)O)c2c3ccc(OC)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O03 compound treatment 1108500.0 403000.0 0.85 1302017.0 532000.0 1.21 1.4593 0.9855 1434813 IFLab1_003831 CC1CN(CCN1S(=O)(=O)c2ccc(Cl)cc2)S(=O)(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O04 compound treatment 1164927.0 460000.0 0.97 1283745.0 514000.0 1.17 1.5145 0.9959 1487527 IFLab1_003832 Cc1ccc(Nc2nnc(s2)c3cc4cc(Cl)ccc4oc3=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O05 compound treatment 1188801.0 483000.0 1.02 1233117.0 463000.0 1.05 1.4689 0.9999 1266519 IFLab1_003833 CC(=O)Nc1ccncc1NC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O06 compound treatment 1260526.0 555000.0 1.18 1285193.0 515000.0 1.17 1.6601 1.0 1565108 IFLab1_003834 COc1ccccc1C2SCCN2S(=O)(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O07 compound treatment 1060763.0 355000.0 0.75 1299449.0 529000.0 1.2 1.3836 0.9746 1321850 IFLab1_003835 CCc1cccc(CC)c1N(COC)C(=O)Cn2cnc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O08 compound treatment 1245998.0 541000.0 1.15 1350698.0 581000.0 1.32 1.7437 0.9975 2067707 IFLab1_003836 Cc1nc(cs1)c2cccc(NC(=O)/C=C\C(=O)O)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O09 compound treatment 1179157.0 474000.0 1.0 1459963.0 690000.0 1.57 1.8191 0.9768 1033879 IFLab1_003837 C(Oc1ccccc1)c2nc3ccccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O10 compound treatment 1149799.0 444000.0 0.94 1402424.0 632000.0 1.44 1.6826 0.979 1381079 IFLab1_003838 CCC(=O)Nc1sc2CCCCCc2c1C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O11 compound treatment 1095770.0 390000.0 0.83 1422120.0 652000.0 1.48 1.6333 0.9621 1281502 IFLab1_003839 CC(C)C(=O)Nc1ccc(cc1)c2nc3ccccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O12 compound treatment 1015278.0 310000.0 0.66 1411640.0 641000.0 1.46 1.4958 0.9351 2067708 IFLab1_003840 C1CN=C(C1)NC2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O13 compound treatment 1124730.0 419000.0 0.89 1351602.0 581000.0 1.32 1.5633 0.9814 1232395 IFLab1_003841 C=CCn1nnnc1SCC(=O)Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O14 compound treatment 1039968.0 335000.0 0.71 1347747.0 578000.0 1.31 1.4301 0.9582 1684284 IFLab1_003842 OC(=O)CN1C(=O)c2cccc3cccc1c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O15 compound treatment 1134048.0 429000.0 0.91 1304780.0 535000.0 1.22 1.502 0.9897 2067709 IFLab1_003843 CN(C1=CC(=O)c2ccccc2C1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O16 compound treatment 1124610.0 419000.0 0.89 1297320.0 527000.0 1.2 1.4759 0.9892 1232143 IFLab1_003844 Cc1ccc(C)c(c1)S(=O)(=O)Nc2ccc(O)c(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O17 compound treatment 1025382.0 320000.0 0.68 1210030.0 440000.0 1.0 1.1868 0.9821 1556147 IFLab1_003845 CCc1ccc(cc1)c2csc(N)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O18 compound treatment 984745.0 279000.0 0.59 1242289.0 472000.0 1.07 1.1778 0.9607 2067710 IFLab1_003846 CCOc1ccc(cc1)S(=O)(=O)NC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O19 compound treatment 1216608.0 511000.0 1.08 1086845.0 317000.0 0.72 1.2754 0.9803 1143616 IFLab1_003847 CN(C1CCS(=O)(=O)C1)C(=O)COc2cccc(Br)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O20 compound treatment 1285417.0 580000.0 1.23 1328156.0 558000.0 1.27 1.7665 0.9999 1687160 IFLab1_003848 NS(=O)(=O)c1ccc2NC(=O)c3cccc1c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O21 compound treatment 1103548.0 398000.0 0.84 1169082.0 399000.0 0.91 1.2382 0.9994 1208892 IFLab1_003849 CCC(Sc1ccc(Cl)cc1)C(=O)Nc2nnc(s2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O22 compound treatment 1043948.0 339000.0 0.72 878519.0 108000.0 0.25 0.6817 0.8984 2067711 IFLab1_003850 COC(=O)CSc1nnc(SCc2ccc(Cl)cc2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O23 mock treatment 920799.0 215000.0 0.46 944455.0 174000.0 0.4 0.6031 0.9975 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 O24 mock treatment 548723.0 -157000.0 -0.33 498555.0 -272000.0 -0.62 -0.6715 -0.9577 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P01 compound treatment 460245.0 -245000.0 -0.52 389788.0 -380000.0 -0.86 -0.979 -0.9703 1460909 IFLab1_003851 OCCN1CCN(CC1)C(c2ccccc2)c3ccc4cccnc4c3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P02 compound treatment 716289.0 10900.0 0.02 471215.0 -299000.0 -0.68 -0.4643 -0.6827 2067712 IFLab1_003852 Cc1ccc(NC(=O)CSC2=NCCN2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P03 compound treatment 928630.0 223000.0 0.47 664859.0 -105000.0 -0.24 0.1653 0.3118 1584511 IFLab1_003853 Cc1ccc(o1)c2csc(NC(=O)c3nc4ccccc4s3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P04 compound treatment 1016633.0 311000.0 0.66 737214.0 -32900.0 -0.07 0.4136 0.6229 2067713 IFLab1_003854 Cc1n[nH]c(O)c1C2=NCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P05 compound treatment 731269.0 25900.0 0.05 829486.0 59300.0 0.13 0.1341 0.9213 2067714 IFLab1_003855 O=C(Nc1ccc2sccc2c1)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P06 compound treatment 1055815.0 350000.0 0.74 875435.0 105000.0 0.24 0.6945 0.8899 2067715 IFLab1_003856 O=C/1N=C(Nc2cccnc2)S\C1=C\c3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P07 compound treatment 883362.0 178000.0 0.38 894665.0 125000.0 0.28 0.4669 0.99 1685961 IFLab1_003857 CCC(=O)Nc1nc2ccc3nc(SC)sc3c2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P08 compound treatment 914285.0 209000.0 0.44 959463.0 189000.0 0.43 0.6174 0.9999 1504525 IFLab1_003858 NC(=O)c1oc2ccccc2c1NC(=O)C(c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P09 compound treatment 833139.0 128000.0 0.27 1124652.0 355000.0 0.81 0.7614 0.8955 2067716 IFLab1_003859 CCCc1nnc(SCC(=O)O)n1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P10 compound treatment 945377.0 240000.0 0.51 1059981.0 290000.0 0.66 0.8257 0.9918 2067717 IFLab1_003860 NC(=O)c1ccc(N/C=C(\C#N)/c2nc(cs2)c3cccc(Br)c3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P11 compound treatment 873218.0 168000.0 0.36 1026854.0 257000.0 0.58 0.6642 0.9718 1312456 IFLab1_003861 COC(=O)c1ccc(NCC(=O)c2ccc(OC)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P12 compound treatment 795784.0 90400.0 0.19 917486.0 147000.0 0.33 0.3723 0.9649 1298903 IFLab1_003862 Cc1ccc2nc(NC(=O)c3ccco3)sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P13 compound treatment 571388.0 -134000.0 -0.28 814429.0 44300.0 0.1 -0.1297 -0.4304 1591687 IFLab1_003863 CC1CCc2c(C(=O)O)c(NC(=O)c3cccs3)sc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P14 compound treatment 945275.0 240000.0 0.51 694785.0 -75400.0 -0.17 0.2384 0.4443 1199813 IFLab1_003864 COc1cccc(OCC(O)CNC(C)c2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P15 compound treatment 883053.0 178000.0 0.38 991089.0 221000.0 0.5 0.6215 0.9899 2067718 IFLab1_003865 OC(=O)COc1ccccc1/C=C\2/SC(=S)N(Cc3ccco3)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P16 compound treatment 966113.0 261000.0 0.55 772460.0 2310.0 0.01 0.3945 0.7138 1241600 IFLab1_003866 OC(COc1ccc(cc1)C2CCCCC2)CN3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P17 compound treatment 877392.0 172000.0 0.36 814992.0 44800.0 0.1 0.3299 0.8714 2067719 IFLab1_003867 Cc1ccc(cc1)N(Sc2ccc(Cl)cc2)C3CS(=O)(=O)C=C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P18 compound treatment 891092.0 186000.0 0.39 843869.0 73700.0 0.17 0.3968 0.9276 1368925 IFLab1_003868 Oc1c(ccc2cccnc12)C(Nc3nccs3)c4ccc(F)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P19 compound treatment 979797.0 274000.0 0.58 689542.0 -80600.0 -0.18 0.2817 0.4619 1589801 IFLab1_003869 CCOc1ccc(cc1)N2C(=O)C3C4CC(C=C4)C3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P20 compound treatment 891308.0 186000.0 0.39 698334.0 -71800.0 -0.16 0.1632 0.3826 1522937 IFLab1_003870 O=C1CC(Sc2nc3ccccc3n12)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P21 compound treatment 836028.0 131000.0 0.28 671020.0 -99100.0 -0.23 0.0364 0.102 2067720 IFLab1_003871 CC(=C)C(=O)Oc1cccc(c1)N2C(=O)C3C4CC(C=C4)C3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P22 compound treatment 836720.0 131000.0 0.28 580215.0 -190000.0 -0.43 -0.1085 -0.2112 1429354 IFLab1_003872 COc1ccc(cc1C(=O)O)S(=O)(=O)N2CCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P23 mock treatment 616494.0 -88900.0 -0.19 544187.0 -226000.0 -0.51 -0.4966 -0.9074 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1422 P24 mock treatment 481870.0 -224000.0 -0.47 466902.0 -303000.0 -0.69 -0.8226 -0.9833 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A01 compound treatment 399179.0 -481000.0 -1.02 545228.0 -307000.0 -0.7 -1.2146 -0.9828 1023263 Maybridge3_000001 OC(=O)c1ccc(Br)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A02 compound treatment 900600.0 20200.0 0.04 712044.0 -140000.0 -0.32 -0.1948 -0.6066 2075164 Maybridge3_000002 CC(C)(C)OC(=O)NC1CCN(CC1)c2nccc(n2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A03 compound treatment 883469.0 3040.0 0.01 855121.0 3120.0 0.01 0.0096 0.9989 2075165 Maybridge3_000003 CC(C)(C)OC(=O)N1CCC(N)(CC1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A04 compound treatment 614511.0 -266000.0 -0.56 634012.0 -218000.0 -0.5 -0.7491 -0.9979 1125505 Maybridge3_000004 CC(=O)Nc1ccc(cc1Cl)S(=O)(=O)N2CCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A05 compound treatment 953042.0 72600.0 0.15 873764.0 21800.0 0.05 0.1438 0.8895 2075166 Maybridge3_000005 FC(F)(F)c1ccnc(SCC(=O)c2cccnc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A06 compound treatment 717172.0 -163000.0 -0.35 652153.0 -200000.0 -0.45 -0.566 -0.991 1209791 Maybridge3_000006 CC(C)(C)OC(=O)NC1CCN(CC1)C(=O)c2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A07 compound treatment 797426.0 -83000.0 -0.18 655036.0 -197000.0 -0.45 -0.4411 -0.9167 2075167 Maybridge3_000007 OC(COc1ccc(F)cc1)CN2CCN(CC2)c3nccc(n3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A08 compound treatment 722151.0 -158000.0 -0.34 630092.0 -222000.0 -0.5 -0.594 -0.9804 2075168 Maybridge3_000008 Fc1cccc(Cl)c1CN2CCN(CCCNc3nccc(n3)C(F)(F)F)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A09 compound treatment 545757.0 -335000.0 -0.71 623591.0 -228000.0 -0.52 -0.8689 -0.9882 2075169 Maybridge3_000009 CC(=O)Nc1ccc(cc1)c2csc(C)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A10 compound treatment 852966.0 -27500.0 -0.06 757994.0 -94000.0 -0.21 -0.1923 -0.8681 1620264 Maybridge3_000010 Cc1nc(nc(N2CCCN(Cc3ccc(F)cc3)CC2)c1Cl)c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A11 compound treatment 743555.0 -137000.0 -0.29 751312.0 -101000.0 -0.23 -0.3671 -0.9931 2075170 Maybridge3_000011 Cc1nc(ccc1c2nnc(SCc3cc(F)cc(F)c3)o2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A12 compound treatment 447540.0 -433000.0 -0.92 473500.0 -379000.0 -0.86 -1.2574 -0.9995 2075171 Maybridge3_000012 Clc1cccc(c1Cl)S(=O)(=O)NCCCN2CCN(Cc3ccccc3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A13 compound treatment 430675.0 -450000.0 -0.95 627845.0 -224000.0 -0.51 -1.0346 -0.9569 1658739 Maybridge3_000013 OC(CNC1CCN(Cc2ccccc2)CC1)CSc3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A14 compound treatment 815238.0 -65200.0 -0.14 753939.0 -98100.0 -0.22 -0.2554 -0.9736 2075172 Maybridge3_000014 Clc1ccc(OCC(=O)NC2=NCCS2)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A15 compound treatment 528066.0 -352000.0 -0.75 535227.0 -317000.0 -0.72 -1.0375 -0.9998 1464531 Maybridge3_000015 CCOC(=O)c1cc(C#N)c(C)nc1N(CC)CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A16 compound treatment 854733.0 -25700.0 -0.05 747888.0 -104000.0 -0.24 -0.2059 -0.8477 2075173 Maybridge3_000016 COc1cc(/C=N/c2cc(C)ccc2NC(=O)C)cc(OC)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A17 compound treatment 864429.0 -16000.0 -0.03 754194.0 -97800.0 -0.22 -0.1812 -0.8057 2075174 Maybridge3_000017 FC(F)(F)c1ccnc(NCCNS(=O)(=O)c2ccccc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A18 compound treatment 913234.0 32800.0 0.07 861702.0 9700.0 0.02 0.0648 0.8877 1167525 Maybridge3_000018 OC(=O)CSC1(CCCCCC1)SCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A19 compound treatment 864643.0 -15800.0 -0.03 819921.0 -32100.0 -0.07 -0.0752 -0.9376 2075175 Maybridge3_000019 Cc1oc(cc1C(=O)O)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A20 compound treatment 832965.0 -47500.0 -0.1 746671.0 -105000.0 -0.24 -0.2405 -0.9258 1575563 Maybridge3_000020 Cc1nc2cc(Cl)ccc2c(=O)n1c3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A21 compound treatment 916729.0 36300.0 0.08 826305.0 -25700.0 -0.06 0.0131 0.1355 2075176 Maybridge3_000021 Cc1nc(ccc1C(=O)NCc2ccccc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A22 compound treatment 985587.0 105000.0 0.22 825479.0 -26500.0 -0.06 0.115 0.4979 1510905 Maybridge3_000022 Clc1ccc(cc1)S(=O)(=O)N(CCc2ccccn2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A23 mock treatment 416299.0 -464000.0 -0.98 562968.0 -289000.0 -0.66 -1.1604 -0.9807 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 A24 mock treatment 452846.0 -428000.0 -0.91 448966.0 -403000.0 -0.92 -1.2889 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B01 compound treatment 281023.0 -599000.0 -1.27 257879.0 -594000.0 -1.35 -1.8537 -0.9995 2075177 Maybridge3_000023 Fc1cccc(NCc2ccc3OCOc3c2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B02 compound treatment 1052260.0 172000.0 0.36 1064668.0 213000.0 0.48 0.5995 0.9903 2075178 Maybridge3_000024 Brc1ccc(cc1)C2=CSc3ccccc3N2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B03 compound treatment 1015966.0 136000.0 0.29 1214156.0 362000.0 0.82 0.7854 0.9006 2075179 Maybridge3_000025 Cn1nc(CC#N)c(C#N)c1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B04 compound treatment 1149538.0 269000.0 0.57 1199133.0 347000.0 0.79 0.9615 0.9873 2075180 Maybridge3_000026 CCOc1ccccc1NC(=O)Oc2ccc(F)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B05 compound treatment 998736.0 118000.0 0.25 975750.0 124000.0 0.28 0.3763 0.9984 2075181 Maybridge3_000027 COc1ccc(cc1)/C(=C/c2cccs2)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B06 compound treatment 1078515.0 198000.0 0.42 1268727.0 417000.0 0.95 0.9669 0.933 1568831 Maybridge3_000028 Fc1cccc2nc(oc(=O)c12)c3cccnc3Oc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B07 compound treatment 1071008.0 191000.0 0.4 1234359.0 382000.0 0.87 0.9004 0.9393 1718012 Maybridge3_000029 COc1cc2CCNC(c3ccccc3)c2cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B08 compound treatment 1071912.0 191000.0 0.41 1130286.0 278000.0 0.63 0.7344 0.977 2075182 Maybridge3_000030 COc1ccc(/N=C\2/NC(C)(C)C(=C)S2)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B09 compound treatment 1187558.0 307000.0 0.65 1197914.0 346000.0 0.79 1.0165 0.9956 1314153 Maybridge3_000031 Nc1cccc(Cl)c1Oc2ccc(cc2)S(=O)(=O)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B10 compound treatment 1053426.0 173000.0 0.37 1168250.0 316000.0 0.72 0.7677 0.9512 2075183 Maybridge3_000032 COC(=O)/C=C/1\S/C(=N\c2cccc(SC)c2)/N(C1=O)c3cccc(SC)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B11 compound treatment 1198654.0 318000.0 0.67 1429658.0 578000.0 1.31 1.4057 0.9521 1136610 Maybridge3_000033 O=C(Oc1ccccc1)c2cccnc2Oc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B12 compound treatment 1122769.0 242000.0 0.51 1332449.0 480000.0 1.09 1.1357 0.9408 2075184 Maybridge3_000034 CC(=O)Nc1cc2cc(NC(=O)C(F)(F)F)ccc2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B13 compound treatment 1210343.0 330000.0 0.7 1210246.0 358000.0 0.81 1.0705 0.9971 1365408 Maybridge3_000035 Cc1ccc2cccc(OC(=O)c3cccnc3Oc4ccccc4)c2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B14 compound treatment 1160078.0 280000.0 0.59 1339142.0 487000.0 1.11 1.2023 0.9571 2075185 Maybridge3_000036 FC(F)(F)C(=O)Nc1nnc(s1)C2CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B15 compound treatment 582663.0 -298000.0 -0.63 599367.0 -253000.0 -0.57 -0.8525 -0.9989 2075186 Maybridge3_000037 CCOC(=O)C1=CNc2ccccc2N=C1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B16 compound treatment 1127124.0 247000.0 0.52 1304781.0 453000.0 1.03 1.0977 0.9507 1144609 Maybridge3_000038 Fc1ccc(NC(=O)Cc2ncon2)c(F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B17 compound treatment 1046055.0 166000.0 0.35 1248576.0 397000.0 0.9 0.8858 0.9155 2075187 Maybridge3_000039 CCOC(=O)c1cc(Cl)c(NC(=O)C(F)(F)F)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B18 compound treatment 1154040.0 274000.0 0.58 1284327.0 432000.0 0.98 1.1052 0.9683 2075188 Maybridge3_000040 Cn1c(nc(=O)c2ccccc12)c3cc(Br)cs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B19 compound treatment 1358438.0 478000.0 1.01 1172465.0 320000.0 0.73 1.2317 0.9869 2075189 Maybridge3_000041 Fc1ccc(cc1Cl)C(=O)Nc2nnc(s2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B20 compound treatment 1020689.0 140000.0 0.3 1208095.0 356000.0 0.81 0.7827 0.9075 2075190 Maybridge3_000042 CC(C)(C)c1nnc(N/C=N/O)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B21 compound treatment 1278681.0 398000.0 0.84 1181033.0 329000.0 0.75 1.126 0.9982 2075191 Maybridge3_000043 C/C=C(\C)/c1nnc(NCC(C)(C)C)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B22 compound treatment 1213838.0 333000.0 0.71 1025763.0 174000.0 0.4 0.7791 0.9622 1193479 Maybridge3_000044 O=C(NCC1CC1)c2ccccc2NC(=O)c3cc4ccccc4oc3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B23 mock treatment 1066078.0 186000.0 0.39 1068170.0 216000.0 0.49 0.6258 0.9939 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 B24 mock treatment 508501.0 -372000.0 -0.79 679390.0 -173000.0 -0.39 -0.835 -0.9481 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C01 compound treatment 854671.0 -25800.0 -0.05 737730.0 -114000.0 -0.26 -0.2223 -0.8374 342762 Maybridge3_000045 COc1ccc2[nH]cc(CCN(C)C)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C02 compound treatment 1036802.0 156000.0 0.33 947724.0 95700.0 0.22 0.3883 0.9792 1121244 Maybridge3_000046 CCOC(=O)c1ccc(cc1)N2C(=O)CC3(CCCC3)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C03 compound treatment 1136204.0 256000.0 0.54 1020715.0 169000.0 0.38 0.6546 0.9856 1252601 Maybridge3_000047 CCN(CC)S(=O)(=O)c1ccc(s1)c2csc(C)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C04 compound treatment 1007038.0 127000.0 0.27 969235.0 117000.0 0.27 0.3783 1.0 2075192 Maybridge3_000048 FC(F)(F)c1ccnc(n1)N2CCC(CC2)NC(=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C05 compound treatment 1076410.0 196000.0 0.42 999641.0 148000.0 0.34 0.5311 0.9944 2075193 Maybridge3_000049 FC(F)(F)c1ccnc(SCC(=O)Nc2ccc(Br)cc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C06 compound treatment 1098597.0 218000.0 0.46 1121972.0 270000.0 0.61 0.761 0.9903 1566490 Maybridge3_000050 CCN(CC)S(=O)(=O)c1ccc(N2C(=O)CC3(CCCC3)C2=O)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C07 compound treatment 1020389.0 140000.0 0.3 1057968.0 206000.0 0.47 0.5409 0.9758 1513220 Maybridge3_000051 CC(C)(C)OC(=O)N1CCCN(CC1)C(=O)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C08 compound treatment 1102273.0 222000.0 0.47 1178416.0 326000.0 0.74 0.8573 0.9758 1121829 Maybridge3_000052 CC(=O)Nc1ccc(cc1Cl)S(=O)(=O)N2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C09 compound treatment 1005336.0 125000.0 0.26 1157443.0 305000.0 0.69 0.6783 0.9126 1309044 Maybridge3_000053 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)N3CCN(Cc4ccccc4)CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C10 compound treatment 1230877.0 350000.0 0.74 1033934.0 182000.0 0.41 0.8178 0.9618 1606977 Maybridge3_000054 COc1cccc(CC(=O)Nc2ccc(cc2)c3csc(C)n3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C11 compound treatment 1090310.0 210000.0 0.44 1112603.0 261000.0 0.59 0.7336 0.99 2075194 Maybridge3_000055 Cc1nc(ccc1c2nnc(SCC=C)o2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C12 compound treatment 1099584.0 219000.0 0.46 1179329.0 327000.0 0.74 0.8547 0.9743 2075195 Maybridge3_000056 FC(F)(F)c1ccnc(n1)N2CCC(CC2)N3C(=O)CC4(CCCC4)C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C13 compound treatment 1219656.0 339000.0 0.72 1315462.0 463000.0 1.05 1.2536 0.9827 2075196 Maybridge3_000057 Cc1nc(ccc1C(=O)Oc2ccc3OCOc3c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C14 compound treatment 1269793.0 389000.0 0.83 1184046.0 332000.0 0.75 1.1175 0.999 2075197 Maybridge3_000058 O=C(Cc1ccccc1)NC2=NCCS2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C15 compound treatment 1013250.0 133000.0 0.28 1175574.0 324000.0 0.74 0.7193 0.9132 2075198 Maybridge3_000059 Cc1nc(ccc1C(=O)NCCc2cccs2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C16 compound treatment 1163599.0 283000.0 0.6 1234723.0 383000.0 0.87 1.0398 0.9836 2075199 Maybridge3_000060 CC(=O)Nc1ccc(C)cc1/N=C/c2ccc3OCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C17 compound treatment 968594.0 88200.0 0.19 1047255.0 195000.0 0.44 0.4461 0.9261 2075200 Maybridge3_000061 FC(F)(F)c1cccc(c1)C(=O)NCCNc2nccc(n2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C18 compound treatment 1084990.0 205000.0 0.43 953434.0 101000.0 0.23 0.4697 0.9563 2075201 Maybridge3_000062 CS(=O)(=O)N1CCc2ccccc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C19 compound treatment 1030323.0 150000.0 0.32 828266.0 -23700.0 -0.05 0.1865 0.5787 1199320 Maybridge3_000063 CCCc1cnc(nc1)N2CCCN(CC2)S(=O)(=O)c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C20 compound treatment 1091735.0 211000.0 0.45 954326.0 102000.0 0.23 0.4812 0.9534 2075202 Maybridge3_000064 CCOC(=O)c1ccc(/N=C/c2ccccn2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C21 compound treatment 947748.0 67300.0 0.14 973696.0 122000.0 0.28 0.2965 0.9526 2075203 Maybridge3_000065 Cc1nc(ccc1C(=O)NCCNc2cccc(n2)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C22 compound treatment 1185649.0 305000.0 0.65 1003383.0 151000.0 0.34 0.7009 0.9563 2075204 Maybridge3_000066 C/C=C(\C)/C(=O)Nc1cc(C)ccc1n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C23 mock treatment 1033168.0 153000.0 0.32 1195382.0 343000.0 0.78 0.781 0.9241 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 C24 mock treatment 614562.0 -266000.0 -0.56 548398.0 -304000.0 -0.69 -0.8866 -0.9949 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D01 compound treatment 349069.0 -531000.0 -1.13 658795.0 -193000.0 -0.44 -1.1071 -0.9157 1722143 Maybridge3_000067 C(Cc1ccccn1)c2c[nH]c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D02 compound treatment 546458.0 -334000.0 -0.71 855005.0 3000.0 0.01 -0.4958 -0.7003 1604322 Maybridge3_000068 Fc1ccccc1C(=O)NCC(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D03 compound treatment 751731.0 -129000.0 -0.27 903167.0 51200.0 0.12 -0.1107 -0.3731 2075205 Maybridge3_000069 Oc1c(Cl)cc(Cl)cc1/C=N/c2c(C#N)c(CC#N)nn2c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D04 compound treatment 715291.0 -165000.0 -0.35 926765.0 74800.0 0.17 -0.1274 -0.3273 2075206 Maybridge3_000070 Fc1ccc(OC(=O)c2cc3ccccc3s2)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D05 compound treatment 721639.0 -159000.0 -0.34 968632.0 117000.0 0.27 -0.0505 -0.1179 2075207 Maybridge3_000071 Cc1ccc(cc1)/C(=C/c2c(F)cccc2Cl)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D06 compound treatment 1052889.0 172000.0 0.37 1116036.0 264000.0 0.6 0.683 0.9717 2075208 Maybridge3_000072 Fc1cccc2nc(oc(=O)c12)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D07 compound treatment 1109553.0 229000.0 0.49 1109946.0 258000.0 0.59 0.7581 0.9956 2075209 Maybridge3_000073 FC(F)(F)C(=O)Nc1ccc(Br)cc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D08 compound treatment 791488.0 -88900.0 -0.19 811693.0 -40300.0 -0.09 -0.1981 -0.9451 2075210 Maybridge3_000074 CC(=O)Nc1ccc(F)cc1Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D09 compound treatment 890892.0 10500.0 0.02 999922.0 148000.0 0.34 0.2535 0.7521 1718995 Maybridge3_000075 COc1ccc2cc(oc2c1)C(=O)c3ccc(Cl)c(C)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D10 compound treatment 1045330.0 165000.0 0.35 1138403.0 286000.0 0.65 0.7076 0.9575 2075211 Maybridge3_000076 Cc1ncc(CSc2nccc(O)n2)c(CO)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D11 compound treatment 1035435.0 155000.0 0.33 1235937.0 384000.0 0.87 0.8496 0.9109 1104602 Maybridge3_000077 COC1(C)CNc2ccccc2C(=O)N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D12 compound treatment 1161386.0 281000.0 0.6 1409112.0 557000.0 1.27 1.3168 0.9408 2075212 Maybridge3_000078 COC(=O)/C=C/1\S/C(=N\c2ccccn2)/N(C1=O)c3cccc(c3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D13 compound treatment 1179840.0 299000.0 0.63 1415795.0 564000.0 1.28 1.3552 0.9475 1064547 Maybridge3_000079 Cc1ccc(cc1)C(=O)CCN2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D14 compound treatment 1199215.0 319000.0 0.68 1189673.0 338000.0 0.77 1.0207 0.998 1517249 Maybridge3_000080 Fc1cccc(CSc2ncc3ccccn23)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D15 compound treatment 1249850.0 369000.0 0.78 1193051.0 341000.0 0.78 1.1021 1.0 1223097 Maybridge3_000081 Cn1sc(=O)c2ccc(cc12)S(=O)(=O)NCCc3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D16 compound treatment 1338360.0 458000.0 0.97 936427.0 84400.0 0.19 0.8222 0.8308 1283484 Maybridge3_000082 O=c1c2cccnc2oc3ccc(cc13)n4cccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D17 compound treatment 1200994.0 321000.0 0.68 1134752.0 283000.0 0.64 0.9351 0.9996 2075213 Maybridge3_000083 Cc1onc(c1C(=O)NCCSC2=NCCN2)c3c(Cl)cccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D18 compound treatment 1103179.0 223000.0 0.47 1194910.0 343000.0 0.78 0.8852 0.9711 2075214 Maybridge3_000084 Brc1csc(c1)c2nc(=O)c3ccccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D19 compound treatment 1156132.0 276000.0 0.58 1084809.0 233000.0 0.53 0.7876 0.9988 2075215 Maybridge3_000085 CC(=Cc1nc2cccc(F)c2c(=O)o1)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D20 compound treatment 1137860.0 257000.0 0.55 1155835.0 304000.0 0.69 0.8743 0.9932 1322517 Maybridge3_000086 Fc1ccc(NC(=O)Cc2nn[nH]n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D21 compound treatment 1352444.0 472000.0 1.0 1043208.0 191000.0 0.43 1.015 0.9303 2075216 Maybridge3_000087 Cc1nnc(NCC(C)(C)C)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D22 compound treatment 1266919.0 386000.0 0.82 955444.0 103000.0 0.24 0.7457 0.8747 2075217 Maybridge3_000088 CCCc1ccc(cc1)c2ccc(cc2)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D23 mock treatment 1226840.0 346000.0 0.73 815109.0 -36900.0 -0.08 0.46 0.6223 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 D24 mock treatment 749653.0 -131000.0 -0.28 609203.0 -243000.0 -0.55 -0.5864 -0.9492 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E01 compound treatment 930159.0 49700.0 0.11 937973.0 86000.0 0.2 0.2128 0.958 1050973 Maybridge3_000089 Cc1ccc2[nH]cc(CCN)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E02 compound treatment 864823.0 -15600.0 -0.03 996866.0 145000.0 0.33 0.2095 0.6329 2075218 Maybridge3_000090 Brc1ccc(cc1)N2C(=O)CC3(CCCC3)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E03 compound treatment 1080110.0 200000.0 0.42 1088359.0 236000.0 0.54 0.6793 0.993 1123698 Maybridge3_000091 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)NCc3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E04 compound treatment 1153436.0 273000.0 0.58 1095455.0 243000.0 0.55 0.8006 0.9998 1231775 Maybridge3_000092 CCOC(=O)c1c(NC(=O)CCC(=O)O)sc(C)c1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E05 compound treatment 1127369.0 247000.0 0.52 1125518.0 274000.0 0.62 0.8099 0.9963 2075219 Maybridge3_000093 OC(=O)CSCC(=O)Nc1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E06 compound treatment 1149367.0 269000.0 0.57 1059649.0 208000.0 0.47 0.737 0.9956 1696466 Maybridge3_000094 Clc1cc(ccc1N2C(=O)CC3(CCCC3)C2=O)S(=O)(=O)N4CCSCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E07 compound treatment 1200079.0 320000.0 0.68 1215218.0 363000.0 0.83 1.0631 0.9952 1470375 Maybridge3_000095 Clc1cccc(c1Cl)S(=O)(=O)N2CCCN(CC2)C(=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E08 compound treatment 1232872.0 352000.0 0.75 1244999.0 393000.0 0.89 1.1601 0.996 2075220 Maybridge3_000096 OC(COc1ccc(/N=C/c2ccc(Cl)cc2)cc1)CN3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E09 compound treatment 1183196.0 303000.0 0.64 1217604.0 366000.0 0.83 1.0416 0.9918 1589430 Maybridge3_000097 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)N3CCCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E10 compound treatment 1196581.0 316000.0 0.67 1309957.0 458000.0 1.04 1.2101 0.9773 2075221 Maybridge3_000098 FC(F)(F)c1ccnc(Oc2ccc(I)cc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E11 compound treatment 1372442.0 492000.0 1.04 1263583.0 412000.0 0.94 1.3992 0.9985 1678944 Maybridge3_000099 Clc1ccc(CN2CCCNCC2)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E12 compound treatment 1541431.0 661000.0 1.4 1590745.0 739000.0 1.68 2.1785 0.9959 2075222 Maybridge3_000100 FC(F)(F)c1ccnc(n1)N2CCC(CC2)C(=O)N3CCSCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E13 compound treatment 1430012.0 550000.0 1.17 1641056.0 789000.0 1.79 2.0924 0.9782 1517901 Maybridge3_000101 OC(COc1ccc(Cl)c(Cl)c1)CN2CCC(O)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E14 compound treatment 1211296.0 331000.0 0.7 1328351.0 476000.0 1.08 1.2618 0.9779 2075223 Maybridge3_000102 COc1cc(/C=C/2\CCCCC2=O)cc(OC)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E15 compound treatment 1086170.0 206000.0 0.44 1315342.0 463000.0 1.05 1.0533 0.9238 2075224 Maybridge3_000103 CCOC(=O)c1cc(/C(=N/O)/N)c(C)nc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E16 compound treatment 1303647.0 423000.0 0.9 1217066.0 365000.0 0.83 1.2213 0.9992 2075225 Maybridge3_000104 CC(=O)Nc1ccc(C)cc1/N=C/c2ccncc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E17 compound treatment 122914.0 -758000.0 -1.61 156208.0 -696000.0 -1.58 -2.2541 -1.0 1127707 Maybridge3_000105 Cc1cc(Cl)cc(Br)c1OCC(O)CNCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E18 compound treatment 1075007.0 195000.0 0.41 1485205.0 633000.0 1.44 1.3096 0.8745 2075226 Maybridge3_000106 CCOC(=O)/C(=C(/C)\Nc1ccc(F)cc1)/C2CC(=O)N(C2=O)c3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E19 compound treatment 1172160.0 292000.0 0.62 1152947.0 301000.0 0.68 0.9211 0.9987 2075227 Maybridge3_000107 COC(=O)c1sccc1Oc2nccc(n2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E20 compound treatment 1169189.0 289000.0 0.61 1029662.0 178000.0 0.4 0.7185 0.9796 2075228 Maybridge3_000108 Oc1ccc(Br)cc1/C=N/c2ccc3[nH]nnc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E21 compound treatment 1120220.0 240000.0 0.51 1111996.0 260000.0 0.59 0.7774 0.9972 2075229 Maybridge3_000109 Cc1nc(ccc1C(=O)N2CCCCC2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E22 compound treatment 1300661.0 420000.0 0.89 1051200.0 199000.0 0.45 0.9502 0.9508 2075230 Maybridge3_000110 C/C=C(\C)/C(=O)Nc1ccc(cc1)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E23 mock treatment 1036095.0 156000.0 0.33 1069025.0 217000.0 0.49 0.5822 0.9809 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 E24 mock treatment 710215.0 -170000.0 -0.36 600355.0 -252000.0 -0.57 -0.6597 -0.9753 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F01 compound treatment 988363.0 108000.0 0.23 808207.0 -43800.0 -0.1 0.0914 0.3662 1295702 Maybridge3_000111 Cc1cc(C)c(NC(=O)CSCc2cnc(C)c(O)c2CO)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F02 compound treatment 1000259.0 120000.0 0.25 1169601.0 318000.0 0.72 0.6902 0.9017 1449189 Maybridge3_000112 Cc1ccccc1C(=O)NCC(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F03 compound treatment 910331.0 29900.0 0.06 1229388.0 377000.0 0.86 0.6515 0.7573 2075231 Maybridge3_000113 Cn1ncc(C#N)c1n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F04 compound treatment 958686.0 78300.0 0.17 1249014.0 397000.0 0.9 0.7556 0.8233 2075232 Maybridge3_000114 COc1ccccc1Oc2ccc(cc2N)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F05 compound treatment 1009532.0 129000.0 0.27 1171682.0 320000.0 0.73 0.7075 0.9109 2075233 Maybridge3_000115 COC(=O)C1SC/C(=N\O)/C1C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F06 compound treatment 966634.0 86200.0 0.18 1430459.0 578000.0 1.32 1.0592 0.7977 1209945 Maybridge3_000116 Fc1ccc(cc1Cl)c2nc3cccc(F)c3c(=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F07 compound treatment 960887.0 80500.0 0.17 1211345.0 359000.0 0.82 0.6983 0.8367 1422600 Maybridge3_000117 Clc1c(sc2ccccc12)C(=O)NCC3CCC(CC3)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F08 compound treatment 1157301.0 277000.0 0.59 1468023.0 616000.0 1.4 1.4054 0.9255 2075234 Maybridge3_000118 Clc1cccc2nc(oc(=O)c12)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F09 compound treatment 1150614.0 270000.0 0.57 1598658.0 747000.0 1.7 1.6054 0.8961 2075235 Maybridge3_000119 Cc1cc(ccc1Cl)C(=O)CSC#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F10 compound treatment 1033707.0 153000.0 0.32 1570757.0 719000.0 1.63 1.3853 0.8314 1399737 Maybridge3_000120 CC(=O)Nc1cc2cc(NC(=O)c3c(F)cccc3F)ccc2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F11 compound treatment 1184752.0 304000.0 0.65 1686849.0 835000.0 1.9 1.7983 0.897 2075236 Maybridge3_000121 Nc1ccc(c(C#N)c1)n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F12 compound treatment 1264285.0 384000.0 0.81 2012269.0 1160000.0 2.64 2.4407 0.8841 2075237 Maybridge3_000122 COC(=O)/C=C/1\S/C(=N\c2ccccn2)/N(C1=O)c3cccc(SC)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F13 compound treatment 1153278.0 273000.0 0.58 1632102.0 780000.0 1.77 1.6631 0.8915 1012037 Maybridge3_000123 O=C(CCN1CCCCC1)c2ccc(cc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F14 compound treatment 1586994.0 707000.0 1.5 1703451.0 851000.0 1.94 2.428 0.992 2075238 Maybridge3_000124 CCc1nc2cc(cc(Cl)c2nc1CC)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F15 compound treatment 1144379.0 264000.0 0.56 1671467.0 819000.0 1.86 1.7131 0.8806 1917196 Maybridge3_000125 FC(F)(F)C(=O)NCCc1ccncc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F16 compound treatment 1175948.0 296000.0 0.63 1153548.0 302000.0 0.69 0.9278 0.999 2075239 Maybridge3_000126 Clc1ccc2OC(Nc2c1)c3ccc(C#N)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F17 compound treatment 1251112.0 371000.0 0.79 1140451.0 288000.0 0.66 1.0194 0.996 2075240 Maybridge3_000127 O=C(NCCSC1=NCCN1)c2cccnc2Oc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F18 compound treatment 1179412.0 299000.0 0.63 1139523.0 288000.0 0.65 0.9104 0.9999 1172488 Maybridge3_000128 O=c1nc([nH]c2ccccc12)c3ccc(C#N)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F19 compound treatment 1204873.0 324000.0 0.69 1070040.0 218000.0 0.5 0.8369 0.9871 1505028 Maybridge3_000129 OC(=O)c1c(F)cccc1NC(=O)COc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F20 compound treatment 1171221.0 291000.0 0.62 1064057.0 212000.0 0.48 0.7768 0.9926 1261208 Maybridge3_000130 Cc1ccc(NC(=O)Cc2nn[nH]n2)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F21 compound treatment 1125582.0 245000.0 0.52 1055063.0 203000.0 0.46 0.6939 0.9983 2075241 Maybridge3_000131 CC(C)c1nnc(NCC(C)(C)C)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F22 compound treatment 1025380.0 145000.0 0.31 1060314.0 208000.0 0.47 0.5522 0.9781 2075242 Maybridge3_000132 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F23 mock treatment 1081023.0 201000.0 0.43 945046.0 93000.0 0.21 0.4503 0.948 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 F24 mock treatment 594908.0 -286000.0 -0.61 581710.0 -270000.0 -0.61 -0.8625 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G01 compound treatment 935444.0 55000.0 0.12 830883.0 -21100.0 -0.05 0.0485 0.3846 2075243 Maybridge3_000133 Oc1ccc(cc1)n2cncn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G02 compound treatment 1086464.0 206000.0 0.44 1082305.0 230000.0 0.52 0.6791 0.9959 1484820 Maybridge3_000134 NCCNc1ncnc2scc(c3ccccc3)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G03 compound treatment 1086463.0 206000.0 0.44 1181987.0 330000.0 0.75 0.8393 0.9669 2075244 Maybridge3_000135 c1csc(c1)c2cc[nH]n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G04 compound treatment 1202626.0 322000.0 0.68 1116805.0 265000.0 0.6 0.9087 0.998 1368451 Maybridge3_000136 CCOC(=O)c1c(sc(C)c1c2ccccc2)N3C(=O)CCC3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G05 compound treatment 1098601.0 218000.0 0.46 958960.0 107000.0 0.24 0.499 0.9549 2075245 Maybridge3_000137 COc1ccc(CCNCC(O)Cn2ccc3ccccc23)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G06 compound treatment 1449647.0 569000.0 1.21 1148563.0 297000.0 0.67 1.33 0.9622 1139862 Maybridge3_000138 Clc1cc(ccc1N2C(=O)CC3(CCCC3)C2=O)S(=O)(=O)NC4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G07 compound treatment 1157873.0 277000.0 0.59 1272447.0 420000.0 0.96 1.0918 0.9728 1263570 Maybridge3_000139 OC(COc1ccc(Cl)c(Cl)c1)CN2CCCN(CC2)C(=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G08 compound treatment 1376530.0 496000.0 1.05 1543457.0 691000.0 1.57 1.8553 0.9809 1720104 Maybridge3_000140 CC(O)CNc1ncnc2scc(c3ccccc3)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G09 compound treatment 1490837.0 610000.0 1.29 1470360.0 618000.0 1.41 1.9091 0.9991 1618125 Maybridge3_000141 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)NCc3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G10 compound treatment 1082226.0 202000.0 0.43 1605576.0 754000.0 1.71 1.514 0.8573 2075246 Maybridge3_000142 CCCc1cnc(nc1)N2CCSCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G11 compound treatment 1103840.0 223000.0 0.47 1956106.0 1100000.0 2.51 2.1099 0.8259 1463644 Maybridge3_000143 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)NCC3CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G12 compound treatment 1674636.0 794000.0 1.68 1988120.0 1140000.0 2.58 3.017 0.9785 2075247 Maybridge3_000144 FC(F)(F)c1ccnc(n1)N2CCC(CC2)C(=O)NC3CCN(Cc4ccccc4)CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G13 compound treatment 1316462.0 436000.0 0.92 1557207.0 705000.0 1.6 1.7873 0.9658 2075248 Maybridge3_000145 Cc1nc(ccc1NC(=O)/C=C/C(=O)O)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G14 compound treatment 1522100.0 642000.0 1.36 1128902.0 277000.0 0.63 1.407 0.9387 2075249 Maybridge3_000146 CC(=O)NS(=O)(=O)c1ccc(/N=C/c2ccccc2O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G15 compound treatment 1196339.0 316000.0 0.67 1347372.0 495000.0 1.13 1.2699 0.9692 1530311 Maybridge3_000147 COC(=O)c1ccc(nc1C)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G16 compound treatment 1094022.0 214000.0 0.45 1661342.0 809000.0 1.84 1.6213 0.8556 1918878 Maybridge3_000148 COc1cc(/C=N/Cc2ccccc2)ccc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G17 compound treatment 1136011.0 256000.0 0.54 1027759.0 176000.0 0.4 0.6657 0.9888 1704746 Maybridge3_000149 Cc1ccc(OCC(O)CNCc2ccccc2)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G18 compound treatment 1280018.0 400000.0 0.85 1726952.0 875000.0 1.99 2.0056 0.9276 2075250 Maybridge3_000150 COc1ccc(/C=N/c2cc(NS(=O)(=O)C)ccc2C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G19 compound treatment 1223742.0 343000.0 0.73 1130105.0 278000.0 0.63 0.9617 0.9975 2075251 Maybridge3_000151 OC(CSc1ccccc1)CN2CCC(CC2)Nc3nccc(n3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G20 compound treatment 1116194.0 236000.0 0.5 1087925.0 236000.0 0.54 0.7327 0.9994 1431187 Maybridge3_000152 Cc1onc(c1C(=O)Nc2ccc(cc2)N3CCOCC3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G21 compound treatment 1245724.0 365000.0 0.77 1082071.0 230000.0 0.52 0.9175 0.9817 2075252 Maybridge3_000153 OC(COc1ccc(Cl)c(Cl)c1)CN2CCC(CC2)Nc3nccc(n3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G22 compound treatment 1153666.0 273000.0 0.58 988434.0 136000.0 0.31 0.6289 0.9572 2075253 Maybridge3_000154 C/C=C(\C)/C(=O)Nc1ccc(Cl)cc1C(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G23 mock treatment 981059.0 101000.0 0.21 1034142.0 182000.0 0.41 0.4437 0.9524 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 G24 mock treatment 686199.0 -194000.0 -0.41 900908.0 48900.0 0.11 -0.2125 -0.4983 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H01 compound treatment 620710.0 -260000.0 -0.55 842333.0 -9670.0 -0.02 -0.4049 -0.7348 2075254 Maybridge3_000155 Cc1ncc(CSCC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(CO)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H02 compound treatment 1113968.0 234000.0 0.5 1099781.0 248000.0 0.56 0.7484 0.9979 2075255 Maybridge3_000156 Fc1ccccc1c2ncc(o2)c3ccc(Br)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H03 compound treatment 1078904.0 198000.0 0.42 1181371.0 329000.0 0.75 0.827 0.9628 2075256 Maybridge3_000157 CC1ONC(=N1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H04 compound treatment 1133936.0 254000.0 0.54 1049949.0 198000.0 0.45 0.6982 0.9961 1588151 Maybridge3_000158 COc1ccc(OC)c(c1)S(=O)(=O)NC2CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H05 compound treatment 1148451.0 268000.0 0.57 1213488.0 361000.0 0.82 0.9829 0.9838 1381483 Maybridge3_000159 Nc1cc(Cl)c(cc1N2CCOCC2)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H06 compound treatment 1452010.0 572000.0 1.21 1406389.0 554000.0 1.26 1.7481 0.9998 1540229 Maybridge3_000160 CC(C)(C)NC(=O)c1cc2ccccc2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H07 compound treatment 1408892.0 528000.0 1.12 1601041.0 749000.0 1.7 1.9964 0.9794 2075257 Maybridge3_000161 Nc1cc(ccc1Oc2ccc(Cl)cc2Cl)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H08 compound treatment 1337993.0 458000.0 0.97 1443683.0 592000.0 1.35 1.6371 0.9871 2075258 Maybridge3_000162 FC(F)(F)c1cccc(c1)c2nc3cccc(Cl)c3c(=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H09 compound treatment 1519026.0 639000.0 1.35 1979868.0 1130000.0 2.56 2.7705 0.9554 2075259 Maybridge3_000163 COc1ccc2ncc(nc2c1)c3ccc(Cl)c(C)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H10 compound treatment 1179628.0 299000.0 0.63 1476192.0 624000.0 1.42 1.452 0.9341 2075260 Maybridge3_000164 Cc1cccc(/N=C/2\NC(C)(C)C(=C)S2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H11 compound treatment 1756340.0 876000.0 1.86 2103089.0 1250000.0 2.84 3.3243 0.9786 2075261 Maybridge3_000165 COc1cccc(C)c1OC(=O)c2cc(F)cc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H12 compound treatment 1711401.0 831000.0 1.76 2031167.0 1180000.0 2.68 3.1413 0.9793 2075262 Maybridge3_000166 COC(=O)/C=C/1\S/C(=N\c2ccccn2)/N(C1=O)c3ccc(C)c(C)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H13 compound treatment 1735032.0 855000.0 1.81 1396122.0 544000.0 1.24 2.1558 0.9827 2075263 Maybridge3_000167 Clc1c(sc2ccccc12)C(=O)Nc3ccc(Br)cn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H14 compound treatment 1572590.0 692000.0 1.47 1838655.0 987000.0 2.24 2.6238 0.9788 2075264 Maybridge3_000168 COC(=O)c1sc2ccccc2c1OC(=O)c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H15 compound treatment 1845593.0 965000.0 2.05 2044137.0 1190000.0 2.71 3.3633 0.9904 1591924 Maybridge3_000169 O=C(CSc1ccccc1)NCc2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H16 compound treatment 1585656.0 705000.0 1.5 1965421.0 1110000.0 2.53 2.8471 0.9684 2075265 Maybridge3_000170 Fc1ccc2nc(cnc2c1)c3ccc(Cl)c(Cl)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H17 compound treatment 1987817.0 1110000.0 2.35 2092913.0 1240000.0 2.82 3.6549 0.9958 2075266 Maybridge3_000171 Cc1nn(nc1C(=O)Nc2cc(Cl)cc(Cl)c2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H18 compound treatment 1591040.0 711000.0 1.51 1393644.0 542000.0 1.23 1.936 0.995 1188919 Maybridge3_000172 Cc1cc(NS(=O)(=O)c2ccc(C)cc2)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H19 compound treatment 1875211.0 995000.0 2.11 1417322.0 565000.0 1.29 2.4 0.9718 2075267 Maybridge3_000173 Fc1cccc2nc(oc(=O)c12)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H20 compound treatment 1331076.0 451000.0 0.96 1187795.0 336000.0 0.76 1.2154 0.9938 2075268 Maybridge3_000174 COC(=O)CSc1cc(C)c(Cl)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H21 compound treatment 1463664.0 583000.0 1.24 1222829.0 371000.0 0.84 1.4704 0.9826 2075269 Maybridge3_000175 COc1ccc(cc1OC)S(=O)(=O)Nc2c(F)cc(F)cc2Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H22 compound treatment 1233054.0 353000.0 0.75 1126814.0 275000.0 0.62 0.9704 0.996 1710792 Maybridge3_000176 COC(=O)c1sccc1OC(=O)c2cc3ccccc3oc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H23 mock treatment 1113663.0 233000.0 0.49 1159371.0 307000.0 0.7 0.8438 0.9856 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 H24 mock treatment 1020034.0 140000.0 0.3 964985.0 113000.0 0.26 0.3909 0.9975 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I01 compound treatment 1186443.0 306000.0 0.65 1056270.0 204000.0 0.46 0.7871 0.9866 1055531 Maybridge3_000177 OCc1c(F)c(F)c(F)c(F)c1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I02 compound treatment 1126173.0 246000.0 0.52 1422339.0 570000.0 1.3 1.2853 0.9197 1169015 Maybridge3_000178 O=C(N1CCCN(Cc2cccc3ccccc23)CC1)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I03 compound treatment 1242225.0 362000.0 0.77 1241767.0 390000.0 0.89 1.1689 0.9974 2075270 Maybridge3_000179 OC(=O)c1ccccc1C(=O)Nc2ccc(cc2)n3nccc3C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I04 compound treatment 1369327.0 489000.0 1.04 1271843.0 420000.0 0.95 1.4078 0.9992 2075271 Maybridge3_000180 O=C(NCCNc1ncnc2scc(c3ccccc3)c12)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I05 compound treatment 1445948.0 566000.0 1.2 1163189.0 311000.0 0.71 1.348 0.9683 1317957 Maybridge3_000181 COc1ccc(Cc2noc(N)n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I06 compound treatment 1599723.0 719000.0 1.52 1236956.0 385000.0 0.88 1.6971 0.9653 1185792 Maybridge3_000182 CC(C)(C)NS(=O)(=O)c1ccc(N2C(=O)CC3(CCCC3)C2=O)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I07 compound treatment 1355391.0 475000.0 1.01 1528350.0 676000.0 1.54 1.7993 0.9789 2075272 Maybridge3_000183 OC(COc1ccc(OC(F)(F)F)cc1)CS(=O)(=O)Cc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I08 compound treatment 1346713.0 466000.0 0.99 1282811.0 431000.0 0.98 1.3916 1.0 1465029 Maybridge3_000184 Cc1ccc(cc1)c2csc3ncnc(N4CCNCC4)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I09 compound treatment 1544179.0 664000.0 1.41 1698978.0 847000.0 1.93 2.3566 0.9881 1557263 Maybridge3_000185 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)NCc3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I10 compound treatment 1397099.0 517000.0 1.1 1446819.0 595000.0 1.35 1.7308 0.9945 2075273 Maybridge3_000186 Oc1ncnc2scc(c3ccc4ccccc4c3)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I11 compound treatment 1420091.0 540000.0 1.14 1684295.0 832000.0 1.89 2.147 0.971 2075274 Maybridge3_000187 CC(C)c1csc2nc[nH]c(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I12 compound treatment 1682992.0 803000.0 1.7 1772563.0 921000.0 2.09 2.683 0.9947 2075275 Maybridge3_000188 CC(O)C/N=C(\C)/c1cc(Cl)ccc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I13 compound treatment 1787577.0 907000.0 1.92 1965311.0 1110000.0 2.53 3.1496 0.9908 2075276 Maybridge3_000189 NC(=O)c1ccc([nH]c1=O)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I14 compound treatment 1762730.0 882000.0 1.87 1409114.0 557000.0 1.27 2.2182 0.982 1310718 Maybridge3_000190 Clc1c(sc2ccccc12)C(=O)N(CCC#N)C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I15 compound treatment 1440901.0 560000.0 1.19 1747363.0 895000.0 2.04 2.2796 0.9671 1523218 Maybridge3_000191 CCOC(=O)c1cc(C#N)c(C)nc1NCC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I16 compound treatment 1244315.0 364000.0 0.77 1376690.0 525000.0 1.19 1.389 0.9777 2075277 Maybridge3_000192 COc1cccc(/C=N/c2ccccc2C(=O)Nc3ccc(F)cc3)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I17 compound treatment 1340226.0 460000.0 0.97 1666131.0 814000.0 1.85 1.9981 0.9551 1376595 Maybridge3_000193 Cc1ccc(OCC(O)CNCc2ccco2)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I18 compound treatment 1296635.0 416000.0 0.88 1260910.0 409000.0 0.93 1.2813 0.9997 2075278 Maybridge3_000194 CCOC(=O)/C(=C(/C)\N)/C1CC(=O)N(C1=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I19 compound treatment 1384347.0 504000.0 1.07 1132048.0 280000.0 0.64 1.2056 0.9694 2075279 Maybridge3_000195 C(Oc1cccnc1)C2=NCCN2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I20 compound treatment 1164494.0 284000.0 0.6 1337441.0 485000.0 1.1 1.2062 0.9594 1152459 Maybridge3_000196 CC(=O)Nc1ccc(NC(=O)c2cccc(Cl)c2)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I21 compound treatment 1379841.0 499000.0 1.06 1178533.0 327000.0 0.74 1.2736 0.9849 2075280 Maybridge3_000197 FC(F)(F)c1ccnc(Sc2ccccc2NC(=O)CSc3ccccn3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I22 compound treatment 1586974.0 707000.0 1.5 1425878.0 574000.0 1.3 1.9817 0.9976 1061675 Maybridge3_000198 CNc1ccc(Cl)cc1C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I23 mock treatment 1077709.0 197000.0 0.42 1190029.0 338000.0 0.77 0.8391 0.9591 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 I24 mock treatment 1070684.0 190000.0 0.4 1192080.0 340000.0 0.77 0.8319 0.954 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J01 compound treatment 908240.0 27800.0 0.06 992610.0 141000.0 0.32 0.2677 0.8236 1327006 Maybridge3_000199 COc1ccccc1NC(=O)CSCc2cnc(C)c(O)c2CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J02 compound treatment 926146.0 45700.0 0.1 1313652.0 462000.0 1.05 0.8107 0.7691 2075281 Maybridge3_000200 Fc1ccccc1c2ncc(o2)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J03 compound treatment 1097293.0 217000.0 0.46 1445667.0 594000.0 1.35 1.2795 0.8973 2075282 Maybridge3_000201 Fc1ccc(NC(=O)CCc2nc(no2)c3ccc(Cl)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J04 compound treatment 1089623.0 209000.0 0.44 1351077.0 499000.0 1.13 1.1159 0.916 2075283 Maybridge3_000202 Clc1cc(Cl)cc(c1)C(=O)NC2CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J05 compound treatment 1276254.0 396000.0 0.84 1403134.0 551000.0 1.25 1.4794 0.981 1160752 Maybridge3_000203 Clc1ccc(cc1)c2csc(=N)n2c3ccccc3N4CCOCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J06 compound treatment 1419241.0 539000.0 1.14 1545741.0 694000.0 1.58 1.923 0.9874 1382622 Maybridge3_000204 O=C(NC1CC1)c2cc3ccccc3oc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J07 compound treatment 1477138.0 597000.0 1.26 1525350.0 673000.0 1.53 1.977 0.9955 1163772 Maybridge3_000205 CS(=O)(=O)N(c1cccc(C#N)c1)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J08 compound treatment 1525236.0 645000.0 1.37 1372874.0 521000.0 1.18 1.804 0.9974 2075284 Maybridge3_000206 Fc1cc(Br)c(c(Br)c1)n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J09 compound treatment 1532597.0 652000.0 1.38 1523281.0 671000.0 1.53 2.0568 0.9988 1391249 Maybridge3_000207 Nc1nc(nc2n(ncc12)c3ccccc3)c4ccncc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J10 compound treatment 1463113.0 583000.0 1.24 1441003.0 589000.0 1.34 1.8204 0.9992 1664843 Maybridge3_000208 Nc1ccc(Cl)cc1C(=O)NCCc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J11 compound treatment 1441677.0 561000.0 1.19 1524485.0 672000.0 1.53 1.9224 0.9923 1510127 Maybridge3_000209 CCOC(=O)c1cc(OC)ccc1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J12 compound treatment 1729535.0 849000.0 1.8 1749241.0 897000.0 2.04 2.7153 0.9981 1404519 Maybridge3_000210 Cc1cc(Oc2c(C)cccc2C)c3ccccc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J13 compound treatment 1426913.0 546000.0 1.16 1491453.0 639000.0 1.45 1.8472 0.9937 1397748 Maybridge3_000211 OC(CCN1CCCCC1)c2ccc(cc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J14 compound treatment 1429545.0 549000.0 1.16 2026884.0 1170000.0 2.67 2.7119 0.9307 2075285 Maybridge3_000212 COC(=O)c1sc2ccccc2c1OC(=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J15 compound treatment 1636788.0 756000.0 1.6 1786078.0 934000.0 2.12 2.6355 0.9904 1205036 Maybridge3_000213 Cc1ccc(SCC(=O)NCc2cccs2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J16 compound treatment 1541188.0 661000.0 1.4 1855177.0 1000000.0 2.28 2.6032 0.9726 1714158 Maybridge3_000214 COc1cc2c(=O)oc(nc2c(OC)c1OC)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J17 compound treatment 1182088.0 302000.0 0.64 1141381.0 289000.0 0.66 0.9174 0.9999 2075286 Maybridge3_000215 CSCc1ccc(cc1)C(=O)Nc2ccc(C)cc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J18 compound treatment 1468287.0 588000.0 1.25 1493560.0 642000.0 1.46 1.9126 0.9969 2075287 Maybridge3_000216 CCOC(=O)c1cc2cc(Cl)ccc2o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J19 compound treatment 1310395.0 430000.0 0.91 1231610.0 380000.0 0.86 1.2548 0.9996 1164150 Maybridge3_000217 Fc1cccc(NC(=O)c2cccs2)c1C(=O)NCc3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J20 compound treatment 1457898.0 577000.0 1.22 1228658.0 377000.0 0.86 1.4712 0.9847 1536952 Maybridge3_000218 O=C(NCC1CC1)c2cc3ccccc3oc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J21 compound treatment 1197993.0 318000.0 0.67 1332680.0 481000.0 1.09 1.2488 0.9729 2075288 Maybridge3_000219 Fc1cc(F)c(NC(=O)c2cccs2)c(C#N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J22 compound treatment 1128941.0 249000.0 0.53 1471546.0 620000.0 1.41 1.3685 0.91 2075289 Maybridge3_000220 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)NN 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J23 mock treatment 1119514.0 239000.0 0.51 1412055.0 560000.0 1.27 1.2588 0.9185 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 J24 mock treatment 944292.0 63900.0 0.14 1272405.0 420000.0 0.96 0.7716 0.7993 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K01 compound treatment 704341.0 -176000.0 -0.37 733103.0 -119000.0 -0.27 -0.4551 -0.9874 2042 Maybridge3_000221 CN(C)c1ncnc2[nH]cnc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K02 compound treatment 895176.0 14700.0 0.03 965520.0 114000.0 0.26 0.2046 0.787 1367399 Maybridge3_000222 OC(=O)C1CCN(CC1)c2ncnc3scc(c4ccccc4)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K03 compound treatment 951329.0 70900.0 0.15 1016938.0 165000.0 0.37 0.3714 0.9194 2075290 Maybridge3_000223 OC(=O)/C=C/C(=O)Nc1ccc(cc1)n2nccc2C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K04 compound treatment 934593.0 54200.0 0.11 951081.0 99100.0 0.23 0.2405 0.9511 2075291 Maybridge3_000224 FC(F)(F)c1ccnc(n1)N2CCC(CC2)NC(=O)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K05 compound treatment 1109219.0 229000.0 0.49 1003006.0 151000.0 0.34 0.5857 0.9857 1276407 Maybridge3_000225 CCOC(=O)C1CCN(CC1)S(=O)(=O)c2ccc(s2)c3csc(C)n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K06 compound treatment 1315740.0 435000.0 0.92 957883.0 106000.0 0.24 0.8228 0.8627 1564123 Maybridge3_000226 Clc1cc(ccc1N2C(=O)CC3(CCCC3)C2=O)S(=O)(=O)NCC4CC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K07 compound treatment 1149639.0 269000.0 0.57 965751.0 114000.0 0.26 0.5864 0.9359 1142977 Maybridge3_000227 CC(C)(C)OC(=O)N1CCCN(CC1)S(=O)(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K08 compound treatment 1426736.0 546000.0 1.16 972352.0 120000.0 0.27 1.0124 0.8507 1445458 Maybridge3_000228 CC(C)(C)OC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K09 compound treatment 1266587.0 386000.0 0.82 933775.0 81800.0 0.19 0.7103 0.8461 1611715 Maybridge3_000229 CC(C)(C)OC(=O)NCCN1C(=O)CC2(CCCC2)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K10 compound treatment 1505349.0 625000.0 1.32 1059610.0 208000.0 0.47 1.2705 0.9034 1158858 Maybridge3_000230 CCCc1cnc(nc1)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K11 compound treatment 1257464.0 377000.0 0.8 1280265.0 428000.0 0.97 1.2537 0.9952 1576456 Maybridge3_000231 OC(CSc1ccc(F)cc1)CN2CCN(CC2)c3nc4ccc(Cl)cc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K12 compound treatment 1259612.0 379000.0 0.8 1083816.0 232000.0 0.53 0.9411 0.979 2075292 Maybridge3_000232 COC(=O)c1ccc(CSc2ccccc2N)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K13 compound treatment 1401731.0 521000.0 1.11 1054129.0 202000.0 0.46 1.1064 0.9244 2075293 Maybridge3_000233 Cc1cn(nc1C(F)(F)F)c2ncnc3scc(c4ccccc4)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K14 compound treatment 1421087.0 541000.0 1.15 1010016.0 158000.0 0.36 1.0645 0.8862 2075294 Maybridge3_000234 Cc1cccc(C)c1/N=C/2\NC3(CCCCC3)C(=C)S2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K15 compound treatment 1462906.0 582000.0 1.23 959831.0 108000.0 0.25 1.0465 0.8313 2075295 Maybridge3_000235 Cc1nc(ccc1C(=O)Oc2ccc(F)cc2F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K16 compound treatment 1383774.0 503000.0 1.07 953940.0 102000.0 0.23 0.9184 0.8411 2075296 Maybridge3_000236 COc1cc(N2C(SCC2=O)c3ccccc3)c(OC)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K17 compound treatment 1280134.0 400000.0 0.85 984282.0 132000.0 0.3 0.8118 0.9029 2075297 Maybridge3_000237 FC(F)(F)c1cccnc1N2CCCN(CC2)S(=O)(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K18 compound treatment 1263189.0 383000.0 0.81 902591.0 50600.0 0.12 0.6551 0.7993 1515242 Maybridge3_000238 CCOC(=O)C1=C(C)NC(=O)C1CC(=O)Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K19 compound treatment 1313657.0 433000.0 0.92 895709.0 43700.0 0.1 0.7197 0.7791 2075298 Maybridge3_000239 Cc1oc(cc1C(=O)NCCNc2nccc(n2)C(F)(F)F)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K20 compound treatment 1155432.0 275000.0 0.58 894547.0 42500.0 0.1 0.4806 0.8133 1249782 Maybridge3_000240 Clc1cccc(c1)C(=O)Nc2ccc3[nH]nnc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K21 compound treatment 1183994.0 304000.0 0.64 873731.0 21700.0 0.05 0.49 0.7591 1077231 Maybridge3_000241 CCOC(=O)C(=C1CCN(Cc2ccccc2)CC1)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K22 compound treatment 1155605.0 275000.0 0.58 952134.0 100000.0 0.23 0.5735 0.9158 1538537 Maybridge3_000242 NC(=O)c1ccccc1NCC(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K23 mock treatment 982498.0 102000.0 0.22 887853.0 35800.0 0.08 0.2106 0.911 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 K24 mock treatment 875198.0 -5230.0 -0.01 920981.0 69000.0 0.16 0.103 0.6554 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L01 compound treatment 601932.0 -278000.0 -0.59 799145.0 -52900.0 -0.12 -0.5025 -0.8339 2075299 Maybridge3_000243 Cc1ncc(CSCC(=O)Nc2cc(ccc2Cl)C(F)(F)F)c(CO)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L02 compound treatment 929655.0 49200.0 0.1 896489.0 44500.0 0.1 0.1453 0.9999 1333099 Maybridge3_000244 O=C(N1CCOCC1)c2cc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L03 compound treatment 925346.0 44900.0 0.1 975753.0 124000.0 0.28 0.2663 0.8965 1117699 Maybridge3_000245 Fc1ccc(NC(=O)c2ccccc2NC(=O)c3ccco3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L04 compound treatment 930743.0 50300.0 0.11 920149.0 68100.0 0.15 0.185 0.9834 2075300 Maybridge3_000246 CCC1(CC)N/C(=N/c2ccc(F)c(Cl)c2)/SC1=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L05 compound treatment 1034056.0 154000.0 0.33 1027643.0 176000.0 0.4 0.5127 0.9949 2075301 Maybridge3_000247 CC(C)(C)n1ncc(C#N)c1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L06 compound treatment 1138981.0 259000.0 0.55 1055118.0 203000.0 0.46 0.7141 0.9964 1495296 Maybridge3_000248 O=C(N1CCCCC1)c2cc3ccccc3oc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L07 compound treatment 1202884.0 322000.0 0.68 1117454.0 265000.0 0.6 0.9101 0.9981 2075302 Maybridge3_000249 N/C(=N\O)/c1cccc(c1)n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L08 compound treatment 1195634.0 315000.0 0.67 1123844.0 272000.0 0.62 0.9095 0.9992 2075303 Maybridge3_000250 Nc1ccc(Oc2ccc(cc2)C(F)(F)F)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L09 compound treatment 1120166.0 240000.0 0.51 1164958.0 313000.0 0.71 0.8625 0.9864 1195614 Maybridge3_000251 CC(C)(C)CC(C)(C)NC(=O)c1cccnc1Oc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L10 compound treatment 1265602.0 385000.0 0.82 1107771.0 256000.0 0.58 0.9886 0.9862 1642557 Maybridge3_000252 Clc1ccc(CCNC(=O)c2cc3ccccc3oc2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L11 compound treatment 1150552.0 270000.0 0.57 1220669.0 369000.0 0.84 0.9976 0.9827 2075304 Maybridge3_000253 OC(=O)CCC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L12 compound treatment 1166105.0 286000.0 0.61 1408754.0 557000.0 1.27 1.3233 0.943 1251326 Maybridge3_000254 COC(=O)c1ccc(Cl)cc1NC(=O)c2cccnc2Oc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L13 compound treatment 1372546.0 492000.0 1.04 1282925.0 431000.0 0.98 1.4305 0.9995 1348369 Maybridge3_000255 Clc1ccccc1C(=O)Nc2ccccc2C(=O)NCc3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L14 compound treatment 1186171.0 306000.0 0.65 1472328.0 620000.0 1.41 1.4556 0.9378 2075305 Maybridge3_000256 CSc1ncc(C#N)c2nc(nn12)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L15 compound treatment 1531928.0 651000.0 1.38 1164410.0 312000.0 0.71 1.4789 0.9522 2075306 Maybridge3_000257 O=C(NCCSc1ccccc1)c2cccnc2Oc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L16 compound treatment 1068627.0 188000.0 0.4 1119681.0 268000.0 0.61 0.7124 0.979 1641688 Maybridge3_000258 Cn1c(nc(=O)c2cc(Cl)ccc12)c3ccc(C#N)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L17 compound treatment 1217314.0 337000.0 0.71 1187185.0 335000.0 0.76 1.0438 0.9995 2075307 Maybridge3_000259 CC1CN(CC(C)O1)C(C#N)c2c(F)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L18 compound treatment 1473458.0 593000.0 1.26 1166625.0 315000.0 0.72 1.3948 0.9643 1370020 Maybridge3_000260 CCOC(=O)c1cc(NC(=O)c2cc3ccccc3oc2=O)sc1CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L19 compound treatment 1166307.0 286000.0 0.61 1078983.0 227000.0 0.52 0.7934 0.9968 2075308 Maybridge3_000261 Fc1cccc(NC(=O)c2cccc(c2)C(F)(F)F)c1C(=O)NCCc3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L20 compound treatment 1301947.0 422000.0 0.89 1114314.0 262000.0 0.6 1.0536 0.9807 1352714 Maybridge3_000262 Cc1nn(nc1C(=O)NCC2CC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L21 compound treatment 1020022.0 140000.0 0.3 905861.0 53900.0 0.12 0.2958 0.9237 2075309 Maybridge3_000263 COC(C/N=C/c1cc(Cl)cc(Cl)c1O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L22 compound treatment 1089713.0 209000.0 0.44 1060445.0 208000.0 0.47 0.6488 0.9995 2075310 Maybridge3_000264 C/C(=C\C(=O)Nc1ccc(F)cc1)/Nc2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L23 mock treatment 1066484.0 186000.0 0.39 876768.0 24800.0 0.06 0.3187 0.7999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 L24 mock treatment 837026.0 -43400.0 -0.09 718202.0 -134000.0 -0.3 -0.2802 -0.8815 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M01 compound treatment 697846.0 -183000.0 -0.39 819939.0 -32100.0 -0.07 -0.3253 -0.8258 2075311 Maybridge3_000265 C(=N/c1cccc2ccccc12)/c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M02 compound treatment 970570.0 90100.0 0.19 897107.0 45100.0 0.1 0.2076 0.9574 2075312 Maybridge3_000266 CC(C)Nc1nccc(n1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M03 compound treatment 1033300.0 153000.0 0.32 895121.0 43100.0 0.1 0.2985 0.8815 2075313 Maybridge3_000267 FC(F)(F)c1ccnc(NCc2ccc(Cl)cc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M04 compound treatment 1063447.0 183000.0 0.39 849566.0 -2440.0 -0.01 0.2704 0.6969 1310185 Maybridge3_000268 OC(CN1CCN(Cc2c(F)cccc2Cl)CC1)Cn3ccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M05 compound treatment 1112530.0 232000.0 0.49 825170.0 -26800.0 -0.06 0.3048 0.6147 1049274 Maybridge3_000269 OC(=O)CC1(CCCC1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M06 compound treatment 1100086.0 220000.0 0.47 847815.0 -4190.0 -0.01 0.3225 0.6925 2075314 Maybridge3_000270 C(Nc1ncnc2scc(c3ccccc3)c12)c4ccccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M07 compound treatment 1196564.0 316000.0 0.67 780062.0 -71900.0 -0.16 0.3582 0.5193 1323196 Maybridge3_000271 Cc1ccc(cc1)S(=O)(=O)N2CCCN(CC2)C(=O)OC(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M08 compound treatment 1230480.0 350000.0 0.74 922718.0 70700.0 0.16 0.6384 0.8408 2075315 Maybridge3_000272 COc1cccc(CC(=O)NC2CCN(CC2)c3nccc(n3)C(F)(F)F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M09 compound treatment 1277550.0 397000.0 0.84 1014624.0 163000.0 0.37 0.8567 0.9318 2075316 Maybridge3_000273 CC(C)(C)OC(=O)N1CCC(O)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M10 compound treatment 1196684.0 316000.0 0.67 1078263.0 226000.0 0.51 0.8378 0.9914 2075317 Maybridge3_000274 Fc1cccc(Cl)c1CN2CCN(CCCNc3nc(ns3)c4ccccc4)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M11 compound treatment 1321357.0 441000.0 0.93 912474.0 60500.0 0.14 0.7582 0.8025 1572373 Maybridge3_000275 OC(CN1CCCC1=O)CN2CCN(CC2)c3nc4ccc(Cl)cc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M12 compound treatment 1510719.0 630000.0 1.34 1003293.0 151000.0 0.34 1.188 0.8611 2075318 Maybridge3_000276 O=C(NC1=NCCS1)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M13 compound treatment 1105280.0 225000.0 0.48 988410.0 136000.0 0.31 0.5563 0.9783 2075319 Maybridge3_000277 Cc1c[nH]nc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M14 compound treatment 1316112.0 436000.0 0.92 981789.0 130000.0 0.3 0.8617 0.8888 1715499 Maybridge3_000278 COc1ccc(NC(=O)C)c(NC(=O)c2ccc(Cl)cc2Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M15 compound treatment 1184602.0 304000.0 0.64 1075908.0 224000.0 0.51 0.8159 0.9931 2075320 Maybridge3_000279 Cc1nc(ccc1C(=O)Sc2ccccc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M16 compound treatment 1228776.0 348000.0 0.74 1014707.0 163000.0 0.37 0.7837 0.9489 2075321 Maybridge3_000280 CCOC(=O)c1cc(C)ccc1/N=C/c2cc(Cl)cc(Cl)c2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M17 compound treatment 1133279.0 253000.0 0.54 986411.0 134000.0 0.31 0.5951 0.9645 2075322 Maybridge3_000281 FC(F)(F)c1ccn(n1)c2ncnc3scc(c4ccccc4)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M18 compound treatment 1287009.0 407000.0 0.86 1043475.0 191000.0 0.44 0.9173 0.95 1397179 Maybridge3_000282 CC(C)N(Cc1ccc(cc1)N(C)C)S(=O)(=O)c2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M19 compound treatment 1316663.0 436000.0 0.92 926073.0 74100.0 0.17 0.773 0.8223 2075323 Maybridge3_000283 Cc1nc(ccc1C(=O)NCCNc2ncccc2C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M20 compound treatment 1274550.0 394000.0 0.84 960618.0 109000.0 0.25 0.7654 0.8785 2075324 Maybridge3_000284 CCc1cc(CC)c(NC(=O)C(C)(C)C)c(CC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M21 compound treatment 1352530.0 472000.0 1.0 1047890.0 196000.0 0.45 1.0226 0.9335 1523751 Maybridge3_000285 C(N1CCCNCC1)c2cccc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M22 compound treatment 1216202.0 336000.0 0.71 945529.0 93500.0 0.21 0.6537 0.8799 2075325 Maybridge3_000286 Oc1ccccc1/C=N/c2cc(ccc2Cl)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M23 mock treatment 1056010.0 176000.0 0.37 755545.0 -96500.0 -0.22 0.1081 0.2503 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 M24 mock treatment 785732.0 -94700.0 -0.2 672572.0 -179000.0 -0.41 -0.4304 -0.9467 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N01 compound treatment 634432.0 -246000.0 -0.52 695965.0 -156000.0 -0.35 -0.6196 -0.9824 2075326 Maybridge3_000287 COc1cccc(OC)c1C(=O)Nc2nnc(s2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N02 compound treatment 1067185.0 187000.0 0.4 1106271.0 254000.0 0.58 0.6887 0.983 2075327 Maybridge3_000288 CC1CCN(CC1)C(=O)c2cc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N03 compound treatment 1044532.0 164000.0 0.35 1181460.0 329000.0 0.75 0.7756 0.9392 2075328 Maybridge3_000289 Brc1cc(Br)c2nc(oc(=O)c2c1)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N04 compound treatment 1134762.0 254000.0 0.54 1168861.0 317000.0 0.72 0.8906 0.9898 2075329 Maybridge3_000290 CCOC(=O)c1cnc(SCC(=O)c2ccc(Cl)c(C)c2)nc1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N05 compound treatment 1149023.0 269000.0 0.57 1099328.0 247000.0 0.56 0.8002 1.0 2075330 Maybridge3_000291 FC(F)(F)c1ccc(N2CCOCC2)c(c1)n3c(csc3=N)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N06 compound treatment 1011196.0 131000.0 0.28 1202481.0 350000.0 0.8 0.7595 0.9002 1320006 Maybridge3_000292 O=C(Nc1ccccc1N2CCOCC2)c3cc4ccccc4oc3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N07 compound treatment 955424.0 75000.0 0.16 1279166.0 427000.0 0.97 0.7991 0.8121 1478773 Maybridge3_000293 Cc1cccc(C)c1NC(=O)CSC(=O)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N08 compound treatment 1110076.0 230000.0 0.49 1213570.0 362000.0 0.82 0.9255 0.9687 1436586 Maybridge3_000294 COC(=O)C=c1sc2nc3ccccc3n2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N09 compound treatment 1241781.0 361000.0 0.77 1211528.0 360000.0 0.82 1.1197 0.9995 1547277 Maybridge3_000295 O=C(N1CCOCC1)c2cccnc2Oc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N10 compound treatment 1107360.0 227000.0 0.48 1216811.0 365000.0 0.83 0.9267 0.9664 2075331 Maybridge3_000296 Clc1ccc(CCNC(=O)c2cccnc2Oc3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N11 compound treatment 1266827.0 386000.0 0.82 1150632.0 299000.0 0.68 1.0593 0.9956 2075332 Maybridge3_000297 N#CCCn1ncc(C#N)c1n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N12 compound treatment 1182547.0 302000.0 0.64 1406132.0 554000.0 1.26 1.3437 0.9508 1620514 Maybridge3_000298 COC(=O)c1ccc(Cl)cc1NC(=O)c2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N13 compound treatment 1327385.0 447000.0 0.95 1283058.0 431000.0 0.98 1.363 0.9999 2075333 Maybridge3_000299 Nc1ccccc1c2nc(no2)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N14 compound treatment 1196648.0 316000.0 0.67 1281302.0 429000.0 0.98 1.1642 0.9832 1246890 Maybridge3_000300 Cc1ccc(NC(=O)Cc2ncon2)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N15 compound treatment 1295491.0 415000.0 0.88 1378102.0 526000.0 1.2 1.468 0.9886 2075334 Maybridge3_000301 FC(F)(F)C(=O)Nc1ccccc1c2nc(no2)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N16 compound treatment 1168699.0 288000.0 0.61 1355625.0 504000.0 1.15 1.2418 0.9568 2075335 Maybridge3_000302 CC1CN(CC(=N)NS(=O)(=O)c2cc(Cl)cc(Cl)c2)CC(C)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N17 compound treatment 1147291.0 267000.0 0.57 1165490.0 313000.0 0.71 0.904 0.9935 2075336 Maybridge3_000303 Cc1nn(nc1C(=O)Oc2ccc(Cl)cc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N18 compound treatment 1373859.0 493000.0 1.05 1422953.0 571000.0 1.3 1.6575 0.9943 1735808 Maybridge3_000304 CCOC(=O)c1cc(CC)sc1NC(=O)c2cccnc2Oc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N19 compound treatment 1375168.0 495000.0 1.05 1163521.0 312000.0 0.71 1.2424 0.9817 2075337 Maybridge3_000305 CCOC(=O)c1c[nH]c2c(F)cc(F)cc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N20 compound treatment 1351920.0 471000.0 1.0 1179477.0 327000.0 0.74 1.2332 0.9895 2075338 Maybridge3_000306 O=C(NCC1CC1)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N21 compound treatment 1399875.0 519000.0 1.1 1182039.0 330000.0 0.75 1.3092 0.9825 1512174 Maybridge3_000307 Cc1cc(C)c(NC(=O)CSCC(=O)c2ccc(Cl)cc2)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N22 compound treatment 1280770.0 400000.0 0.85 1096742.0 245000.0 0.56 0.9936 0.979 2075339 Maybridge3_000308 Cc1cc(no1)N2C(=O)C=CC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N23 mock treatment 1198179.0 318000.0 0.67 899575.0 47600.0 0.11 0.5528 0.8103 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 N24 mock treatment 916628.0 36200.0 0.08 773689.0 -78300.0 -0.18 -0.0716 -0.3695 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O01 compound treatment 583181.0 -297000.0 -0.63 516699.0 -335000.0 -0.76 -0.9846 -0.9955 2075340 Maybridge3_000309 CCOc1nc(N)nc(NC)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O02 compound treatment 1185428.0 305000.0 0.65 1004389.0 152000.0 0.35 0.7022 0.9572 2075341 Maybridge3_000310 FC(F)(F)c1ccnc(NCc2ccc3OCOc3c2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O03 compound treatment 1209861.0 329000.0 0.7 1074918.0 223000.0 0.51 0.8522 0.9876 2075342 Maybridge3_000311 Nc1ccccc1Sc2ncnc3scc(c4ccccc4)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O04 compound treatment 1360037.0 480000.0 1.02 1121462.0 269000.0 0.61 1.1521 0.9706 2075343 Maybridge3_000312 OC(=O)/C=C/C(=O)N1CCCN(CC1)c2ncccc2C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O05 compound treatment 1104927.0 224000.0 0.48 1064056.0 212000.0 0.48 0.6774 1.0 2075344 Maybridge3_000313 OC(CSc1ccccc1)CN2CCN(CC2)c3nccc(n3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O06 compound treatment 1343862.0 463000.0 0.98 1140466.0 288000.0 0.66 1.1584 0.9807 2075345 Maybridge3_000314 NC1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O07 compound treatment 1214323.0 334000.0 0.71 1176083.0 324000.0 0.74 1.0215 0.9998 1468130 Maybridge3_000315 CC(C)(C)OC(=O)N1CCCN(CC1)C(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O08 compound treatment 1324072.0 444000.0 0.94 1243695.0 392000.0 0.89 1.2947 0.9996 2075346 Maybridge3_000316 Cc1nc(ccc1NC(=O)C(F)(F)Sc2ccccc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O09 compound treatment 1338648.0 458000.0 0.97 1199142.0 347000.0 0.79 1.245 0.9947 2075347 Maybridge3_000317 Cc1nc(ccc1c2nnc(SC(=O)c3ccc(Cl)cc3)o2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O10 compound treatment 1372985.0 493000.0 1.04 1197057.0 345000.0 0.78 1.2931 0.9901 2075348 Maybridge3_000318 O=C(NCCCN1CCN(Cc2ccccc2)CC1)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O11 compound treatment 1114574.0 234000.0 0.5 1194548.0 343000.0 0.78 0.9017 0.9763 1676831 Maybridge3_000319 OC(CN1CCN(CC1)c2nc3ccc(Cl)cc3s2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O12 compound treatment 1242388.0 362000.0 0.77 1233587.0 382000.0 0.87 1.156 0.9981 2075349 Maybridge3_000320 O=C(NC1=NCCS1)c2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O13 compound treatment 1145284.0 265000.0 0.56 1155275.0 303000.0 0.69 0.8846 0.9948 2075350 Maybridge3_000321 Cc1nc(ccc1NC(=O)c2ccc(cc2)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O14 compound treatment 1051943.0 172000.0 0.36 1254817.0 403000.0 0.92 0.9047 0.9181 1366003 Maybridge3_000322 COc1nc(Nc2ccc(F)cc2)nc(OC)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O15 compound treatment 1211533.0 331000.0 0.7 1242151.0 390000.0 0.89 1.1235 0.9933 2075351 Maybridge3_000323 FC(F)(F)c1ccnc(NCCNC(=O)C2CC2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O16 compound treatment 1132673.0 252000.0 0.53 1190945.0 339000.0 0.77 0.923 0.9841 1016138 Maybridge3_000324 OC(=O)CSC1(CCCCC1)SCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O17 compound treatment 1189447.0 309000.0 0.66 1248132.0 396000.0 0.9 1.1001 0.9878 2075352 Maybridge3_000325 FC(F)(F)c1ccn(n1)c2nc(ns2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O18 compound treatment 1184299.0 304000.0 0.64 1238592.0 387000.0 0.88 1.077 0.9883 1123304 Maybridge3_000326 CC(C)N(Cc1ccc(cc1)N(C)C)C(=O)c2c(C)onc2c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O19 compound treatment 1369730.0 489000.0 1.04 1115664.0 264000.0 0.6 1.1573 0.966 2075353 Maybridge3_000327 Clc1ccc(cc1)S(=O)(=O)N2CCN=C2COc3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O20 compound treatment 1271879.0 391000.0 0.83 1054055.0 202000.0 0.46 0.9116 0.9611 1029792 Maybridge3_000328 C(CN1CCCCC1)C2CCCCN2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O21 compound treatment 1317998.0 438000.0 0.93 1174561.0 323000.0 0.73 1.1745 0.9932 2075354 Maybridge3_000329 OC(=O)c1ccccc1C(=O)N2CCCN(CC2)c3ncccc3C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O22 compound treatment 1268204.0 388000.0 0.82 958057.0 106000.0 0.24 0.7518 0.8775 1537726 Maybridge3_000330 O=C(Nc1ccc2OCOCc2c1)c3cc4ccccc4oc3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O23 mock treatment 1119410.0 239000.0 0.51 932210.0 80200.0 0.18 0.4872 0.9048 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 O24 mock treatment 646032.0 -234000.0 -0.5 476089.0 -376000.0 -0.85 -0.9557 -0.9667 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P01 compound treatment 479689.0 -401000.0 -0.85 460551.0 -391000.0 -0.89 -1.23 -0.9997 2075355 Maybridge3_000331 CCOC(=O)CCc1ccc2OC(Nc2c1)c3ccc(cc3)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P02 compound treatment 668468.0 -212000.0 -0.45 516749.0 -335000.0 -0.76 -0.8567 -0.9682 2075356 Maybridge3_000332 Cc1ccc(NC(=O)Oc2ccc(F)cc2Cl)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P03 compound treatment 545950.0 -334000.0 -0.71 790856.0 -61100.0 -0.14 -0.5997 -0.8299 1270266 Maybridge3_000333 Brc1cc(Br)c2nc(oc(=O)c2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P04 compound treatment 975493.0 95100.0 0.2 869495.0 17500.0 0.04 0.1706 0.8306 2075357 Maybridge3_000334 CCOC(=O)c1cnc(SCC(=O)c2ccc(cc2)c3ccccc3)nc1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P05 compound treatment 964192.0 83800.0 0.18 930528.0 78500.0 0.18 0.2518 1.0 2075358 Maybridge3_000335 C/C=C(\C)/C(=O)Nc1nncs1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P06 compound treatment 1056752.0 176000.0 0.37 942490.0 90500.0 0.21 0.4098 0.9604 2075359 Maybridge3_000336 CCC1(CC)N/C(=N/c2ccc(C)cc2C)/SC1=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P07 compound treatment 1006086.0 126000.0 0.27 1088229.0 236000.0 0.54 0.5681 0.9477 1310840 Maybridge3_000337 OC(=O)c1cnc2c(F)cccc2c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P08 compound treatment 910813.0 30400.0 0.06 993280.0 141000.0 0.32 0.2727 0.8323 2075360 Maybridge3_000338 COC(=O)/C=C/1\S/C(=N\c2ccc(Cl)cc2)/N(C1=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P09 compound treatment 949433.0 69000.0 0.15 1098136.0 246000.0 0.56 0.4991 0.863 2075361 Maybridge3_000339 O=C(Sc1ccccc1)c2cccnc2Oc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P10 compound treatment 968917.0 88500.0 0.19 1132838.0 281000.0 0.64 0.5841 0.8778 1600278 Maybridge3_000340 CC(=O)Nc1cc2cc(ccc2oc1=O)n3cccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P11 compound treatment 1099181.0 219000.0 0.46 1147862.0 296000.0 0.67 0.8035 0.9835 1726788 Maybridge3_000341 CC(=O)Nc1cc2cc(N)ccc2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P12 compound treatment 1087577.0 207000.0 0.44 920357.0 68400.0 0.16 0.4204 0.9025 1372903 Maybridge3_000342 Cc1onc(c1C(=O)Nc2nnc(s2)C3CC3)c4c(F)cccc4Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P13 compound treatment 984259.0 104000.0 0.22 833396.0 -18600.0 -0.04 0.1257 0.5609 2075362 Maybridge3_000343 CN(C)c1ccc(CC(C#N)C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P14 compound treatment 1014683.0 134000.0 0.28 1211924.0 360000.0 0.82 0.7799 0.9002 1525163 Maybridge3_000344 Clc1cc(Cl)cc(NC(=O)Cc2ncon2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P15 compound treatment 1133949.0 254000.0 0.54 1205855.0 354000.0 0.8 0.9489 0.9808 1394189 Maybridge3_000345 Cc1onc(c1C(=O)NCCS(=O)(=O)c2ccccc2)c3c(Cl)cccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P16 compound treatment 1092327.0 212000.0 0.45 1183511.0 332000.0 0.75 0.8506 0.9694 2075363 Maybridge3_000346 Clc1cc(Cl)cc(c1)S(=O)(=O)NC(=N)CN2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P17 compound treatment 977151.0 96700.0 0.21 1049518.0 198000.0 0.45 0.4625 0.9369 2075364 Maybridge3_000347 Cc1nn(nc1C(=O)Sc2ccccn2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P18 compound treatment 1167005.0 287000.0 0.61 1074841.0 223000.0 0.51 0.7878 0.9959 1025104 Maybridge3_000348 CSC(=S)Nc1ccc(Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P19 compound treatment 904394.0 24000.0 0.05 835367.0 -16600.0 -0.04 0.0092 0.1448 1192638 Maybridge3_000349 CCOC(=O)c1cnc2c(F)cc(F)cc2c1N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P20 compound treatment 904949.0 24500.0 0.05 877435.0 25400.0 0.06 0.0776 0.9986 1166619 Maybridge3_000350 Fc1ccc(c(F)c1)S(=O)(=O)NCC2CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P21 compound treatment 924491.0 44100.0 0.09 782577.0 -69400.0 -0.16 -0.0456 -0.2484 2075365 Maybridge3_000351 Fc1ccc(OC(=O)c2c(Cl)cccc2Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P22 compound treatment 765104.0 -115000.0 -0.24 631519.0 -220000.0 -0.5 -0.5273 -0.9455 2075366 Maybridge3_000352 Clc1ccc2sc(Oc3cccc(c3)N4CCOCC4)nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P23 mock treatment 621898.0 -259000.0 -0.55 646421.0 -206000.0 -0.47 -0.7181 -0.9969 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1431 P24 mock treatment 565347.0 -315000.0 -0.67 454549.0 -397000.0 -0.9 -1.1113 -0.9889 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A01 compound treatment 436430.0 -334000.0 -0.71 517149.0 -210000.0 -0.48 -0.8372 -0.9816 2075367 Maybridge3_000353 Nc1nnc(Sc2nc3cc(Cl)ccc3s2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A02 compound treatment 480466.0 -290000.0 -0.61 618997.0 -108000.0 -0.25 -0.6075 -0.919 1354581 Maybridge3_000354 CCCSc1nc(=O)c2cccnc2n1c3ccc(OC)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A03 compound treatment 491702.0 -278000.0 -0.59 448208.0 -279000.0 -0.63 -0.8652 -0.9994 2075368 Maybridge3_000355 Cc1nn(C)c2oc(=O)cc(c3ccccc3)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A04 compound treatment 571785.0 -198000.0 -0.42 605704.0 -121000.0 -0.28 -0.4919 -0.979 2075369 Maybridge3_000356 Cc1ccc(cc1)S(=O)(=O)CC(=O)Nc2ccc(F)c(F)c2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A05 compound treatment 558221.0 -212000.0 -0.45 583289.0 -144000.0 -0.33 -0.5483 -0.9878 2075370 Maybridge3_000357 CCOC(=O)CSc1cc(C)c(Cl)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A06 compound treatment 580943.0 -189000.0 -0.4 578101.0 -149000.0 -0.34 -0.5226 -0.9964 1298817 Maybridge3_000358 CC(C)(C)c1cc(cc(c1)C(=O)Oc2cccnc2)C(=O)Oc3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A07 compound treatment 528889.0 -241000.0 -0.51 577249.0 -150000.0 -0.34 -0.602 -0.9804 2075371 Maybridge3_000359 CN(C(=O)CSc1cc(Cl)ccc1Cl)c2ccc(F)cc2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A08 compound treatment 535658.0 -234000.0 -0.5 651403.0 -75500.0 -0.17 -0.4726 -0.8992 2075372 Maybridge3_000360 COc1cc(C)nc2nc(SC)nn12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A09 compound treatment 537463.0 -233000.0 -0.49 712805.0 -14100.0 -0.03 -0.3712 -0.7514 1661500 Maybridge3_000361 CC(=O)Nc1ccccc1c2nnc(o2)c3ccc(cc3)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A10 compound treatment 554961.0 -215000.0 -0.46 621076.0 -106000.0 -0.24 -0.4925 -0.9554 1284592 Maybridge3_000362 COC(=O)CNC(=O)c1cccnc1Sc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A11 compound treatment 476355.0 -294000.0 -0.62 513500.0 -213000.0 -0.49 -0.7832 -0.9924 1345631 Maybridge3_000363 Cc1onc(c1NC(=O)Oc2ccc(CC#N)cc2)c3c(F)cccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A12 compound treatment 429765.0 -340000.0 -0.72 507705.0 -219000.0 -0.5 -0.8624 -0.9837 2075373 Maybridge3_000364 CSc1ncccc1C2=N/C(=C\c3ccc(cc3)C(F)(F)F)/C(=O)O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A13 compound treatment 508207.0 -262000.0 -0.55 577571.0 -149000.0 -0.34 -0.6325 -0.9722 2075374 Maybridge3_000365 Clc1ccc(cc1)S(=O)(=O)n2ccc(c2)c3cnc4ccccc4n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A14 compound treatment 622876.0 -147000.0 -0.31 557220.0 -170000.0 -0.39 -0.4933 -0.9944 1474356 Maybridge3_000366 Clc1cccc(c1)C(=O)OCCS(=O)(=O)c2ccccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A15 compound treatment 700364.0 -69600.0 -0.15 521654.0 -205000.0 -0.47 -0.4343 -0.8875 2075375 Maybridge3_000367 O/N=C/Nc1cc(Cl)c(cc1Cl)n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A16 compound treatment 742886.0 -27100.0 -0.06 571478.0 -155000.0 -0.35 -0.2905 -0.8115 2075376 Maybridge3_000368 CSC1=C(C#N)C(=C(C#N)C#N)NC(=N1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A17 compound treatment 732157.0 -37800.0 -0.08 553492.0 -173000.0 -0.39 -0.3355 -0.8339 2075377 Maybridge3_000369 Clc1cncc(Oc2ccc(cn2)n3cccc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A18 compound treatment 658152.0 -112000.0 -0.24 563838.0 -163000.0 -0.37 -0.4298 -0.9767 1401952 Maybridge3_000370 CCOC(=O)c1c(C)c(C#N)c(N)n1c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A19 compound treatment 1000854.0 231000.0 0.49 951686.0 225000.0 0.51 0.7075 0.9998 2075378 Maybridge3_000371 FC(F)(F)c1ccc(SCCNC(=O)c2ccc(Cl)cc2)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A20 compound treatment 860429.0 90400.0 0.19 912804.0 186000.0 0.42 0.4344 0.936 1135908 Maybridge3_000372 CN(C(=O)CSc1ccccn1)c2c3CCCCc3nn2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A21 compound treatment 763432.0 -6570.0 -0.01 818518.0 91600.0 0.21 0.1375 0.6584 2075379 Maybridge3_000373 CC(=C)C(=O)Nc1ccc(Oc2ccc(F)cc2)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A22 compound treatment 585422.0 -185000.0 -0.39 482525.0 -244000.0 -0.56 -0.6695 -0.9853 2075380 Maybridge3_000374 Cn1nc(OC(C)(C)C(=O)O)cc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A23 mock treatment 537912.0 -232000.0 -0.49 464015.0 -263000.0 -0.6 -0.7705 -0.9953 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 A24 mock treatment 471822.0 -298000.0 -0.63 425422.0 -301000.0 -0.69 -0.9316 -0.9992 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B01 compound treatment 491465.0 -279000.0 -0.59 532293.0 -195000.0 -0.44 -0.7304 -0.9899 1206250 Maybridge3_000375 OC(=O)C1CC1C(=O)Nc2ccc(Oc3ccc(F)cc3)nc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B02 compound treatment 829814.0 59800.0 0.13 773916.0 47000.0 0.11 0.1653 0.9964 1921490 Maybridge3_000376 O=C(Nc1ccccc1)/C=C/c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B03 compound treatment 1061574.0 292000.0 0.62 1047350.0 320000.0 0.73 0.9523 0.9967 2075381 Maybridge3_000377 COc1ccc(cc1)/C(=C/c2cn[nH]c2)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B04 compound treatment 1219617.0 450000.0 0.95 1140949.0 414000.0 0.94 1.3397 1.0 1002705 Maybridge3_000378 CC1(C)OC2OC(C(O)CO)C(O)C2O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B05 compound treatment 1291112.0 521000.0 1.1 1197055.0 470000.0 1.07 1.537 0.9999 2075382 Maybridge3_000379 O/N=C/c1c[nH]c(n1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B06 compound treatment 1329081.0 559000.0 1.19 1000032.0 273000.0 0.62 1.2772 0.9545 1260437 Maybridge3_000380 O=C(N(c1ccccc1)c2ccccc2)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B07 compound treatment 1244453.0 474000.0 1.01 902145.0 175000.0 0.4 0.993 0.9178 2075383 Maybridge3_000381 CCCc1cc(=O)c2ccc(OC/C(=N/O)/C)cc2o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B08 compound treatment 1277788.0 508000.0 1.08 1008387.0 282000.0 0.64 1.2137 0.9692 1425483 Maybridge3_000382 CCC(=O)c1ccc(NC(=O)C)cc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B09 compound treatment 1239989.0 470000.0 1.0 1159558.0 433000.0 0.98 1.4001 1.0 1184940 Maybridge3_000383 OCc1cc(=O)c(OCc2ccccc2)c[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B10 compound treatment 1214065.0 444000.0 0.94 961961.0 235000.0 0.53 1.0436 0.964 2075384 Maybridge3_000384 CSC1=N/C(=C/c2cccs2)/C(=O)N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B11 compound treatment 1126314.0 356000.0 0.76 1011209.0 284000.0 0.65 0.9912 0.997 1153981 Maybridge3_000385 CC(O)c1ccccc1c2ccccc2C(C)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B12 compound treatment 1274079.0 504000.0 1.07 1018466.0 292000.0 0.66 1.2244 0.9736 1084431 Maybridge3_000386 CC1(CC1(Br)Br)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B13 compound treatment 1144462.0 374000.0 0.79 1006119.0 279000.0 0.63 1.0102 0.9939 1452761 Maybridge3_000387 O=C(N1CCCCC1)c2cccc3C(=O)c4ccccc4-c32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B14 compound treatment 1107331.0 337000.0 0.72 1140005.0 413000.0 0.94 1.1698 0.9909 1006126 Maybridge3_000388 COC(=O)c1cccc2-c3ccccc3C(=O)c21 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B15 compound treatment 1376651.0 607000.0 1.29 1077518.0 351000.0 0.8 1.4731 0.9736 1691637 Maybridge3_000389 CCc1ccc(cc1)n2nnnc2c3cn[nH]c3c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B16 compound treatment 1215410.0 445000.0 0.94 1193192.0 466000.0 1.06 1.4173 0.9983 1020878 Maybridge3_000390 CNC(=O)Oc1cccc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B17 compound treatment 1182853.0 413000.0 0.88 1157245.0 430000.0 0.98 1.3107 0.9985 1294341 Maybridge3_000391 CCNC(=O)c1ccccc1Sc2ccccc2COC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B18 compound treatment 1422287.0 652000.0 1.38 916676.0 190000.0 0.43 1.2829 0.8856 1016816 Maybridge3_000392 CC(=O)NC(CCc1ccccc1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B19 compound treatment 1419473.0 649000.0 1.38 978683.0 252000.0 0.57 1.3784 0.9244 1511758 Maybridge3_000393 CC(=O)NCc1ccccc1S(=O)c2ccccc2C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B20 compound treatment 1463206.0 693000.0 1.47 1198429.0 472000.0 1.07 1.7972 0.988 1461606 Maybridge3_000394 COc1ccc(cc1)N(C(=C)C2CC2)C(=O)c3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B21 compound treatment 1436190.0 666000.0 1.41 1068813.0 342000.0 0.78 1.5483 0.9604 1115519 Maybridge3_000395 CSc1nc2nc(C)cc(O)n2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B22 compound treatment 1359696.0 590000.0 1.25 920600.0 194000.0 0.44 1.1954 0.9019 1178621 Maybridge3_000396 COn1c2CCCCc2c3c1ccc4nonc43 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B23 mock treatment 1186481.0 416000.0 0.88 1030287.0 303000.0 0.69 1.1121 0.9925 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 B24 mock treatment 505737.0 -264000.0 -0.56 458757.0 -268000.0 -0.61 -0.8272 -0.9991 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C01 compound treatment 517210.0 -253000.0 -0.54 483187.0 -244000.0 -0.55 -0.7707 -0.9999 2075385 Maybridge3_000397 Cc1cc(C)n(n1)c2ccc(nn2)N3CCSCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C02 compound treatment 879291.0 109000.0 0.23 704188.0 -22700.0 -0.05 0.1273 0.5365 2075386 Maybridge3_000398 CN(c1ccc(Br)cc1)c2nc(=O)c3cccnc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C03 compound treatment 1085136.0 315000.0 0.67 1078336.0 351000.0 0.8 1.0374 0.996 1582616 Maybridge3_000399 CCOC(=O)Cc1csc(NS(=O)(=O)c2cc(C)c(Cl)cc2Cl)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C04 compound treatment 1273622.0 504000.0 1.07 1177377.0 450000.0 1.02 1.4792 0.9998 2075387 Maybridge3_000400 Fc1ccc(cc1Cl)S(=O)(=O)/C=C/c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C05 compound treatment 1227999.0 458000.0 0.97 1186685.0 460000.0 1.05 1.4257 0.9993 1293762 Maybridge3_000401 Cc1cc(Oc2ncccc2C(=O)O)cc(C)c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C06 compound treatment 1298753.0 529000.0 1.12 1149045.0 422000.0 0.96 1.4713 0.997 2075388 Maybridge3_000402 Cc1ccc(NC(=O)OCCS(=O)(=O)c2ccc(cn2)C(F)(F)F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C07 compound treatment 1155709.0 386000.0 0.82 1177562.0 451000.0 1.02 1.3027 0.9937 2075389 Maybridge3_000403 O/N=C/Nc1ccccc1Sc2nc3cc(Cl)ccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C08 compound treatment 1109372.0 339000.0 0.72 991686.0 265000.0 0.6 0.9344 0.9961 2075390 Maybridge3_000404 OC(=O)CSc1cccc(Cl)c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C09 compound treatment 1173938.0 404000.0 0.86 1156460.0 430000.0 0.98 1.2961 0.9979 1053033 Maybridge3_000405 O=S(=O)(c1ccccc1)n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C10 compound treatment 1020816.0 251000.0 0.53 1001301.0 274000.0 0.62 0.8171 0.9968 1189912 Maybridge3_000406 COC(=O)CNC(=O)c1cccnc1Sc2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C11 compound treatment 1075886.0 306000.0 0.65 1191811.0 465000.0 1.06 1.206 0.9725 2075391 Maybridge3_000407 Clc1cc2ncc(nc2cc1Cl)c3ccn(c3)S(=O)(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C12 compound treatment 1132002.0 362000.0 0.77 963919.0 237000.0 0.54 0.9237 0.985 1216248 Maybridge3_000408 OC(=O)CNC(=O)c1cccnc1Sc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C13 compound treatment 1167890.0 398000.0 0.84 1289220.0 562000.0 1.28 1.5005 0.9796 1597701 Maybridge3_000409 Cc1cccc(NC(=O)c2ccc(Cl)cc2N)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C14 compound treatment 1030502.0 261000.0 0.55 1040473.0 314000.0 0.71 0.8946 0.992 2075392 Maybridge3_000410 CSc1nc(nc(SC)c1C#N)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C15 compound treatment 1083970.0 314000.0 0.67 988919.0 262000.0 0.6 0.8919 0.9985 1676336 Maybridge3_000411 CSc1nnc(SC)n1CCNC(=O)c2cccc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C16 compound treatment 1022153.0 252000.0 0.53 936091.0 209000.0 0.48 0.7143 0.9983 2075393 Maybridge3_000412 CN(C)c1nc(nc(c1C#N)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C17 compound treatment 972452.0 202000.0 0.43 946801.0 220000.0 0.5 0.657 0.9971 2075394 Maybridge3_000413 COc1ccc(cc1)n2cc(C#N)c(N)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C18 compound treatment 1155679.0 386000.0 0.82 905041.0 178000.0 0.41 0.8646 0.9475 2075395 Maybridge3_000414 CCOC(=O)c1c(C)c(C#N)c(n2cccc2)n1c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C19 compound treatment 1262856.0 493000.0 1.04 1032625.0 306000.0 0.7 1.2303 0.9804 2075396 Maybridge3_000415 OCCS(=O)(=O)c1ccc(cn1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C20 compound treatment 1031187.0 261000.0 0.55 1092475.0 366000.0 0.83 0.9793 0.9805 1461156 Maybridge3_000416 COc1ccc(Sc2nc(C)c(cc2C#N)c3csc(C)n3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C21 compound treatment 1074825.0 305000.0 0.65 1038568.0 312000.0 0.71 0.958 0.9989 2075397 Maybridge3_000417 FC(F)(F)c1ccc(SCC(=O)c2cccc(c2)C(F)(F)F)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C22 compound treatment 1362912.0 593000.0 1.26 897570.0 171000.0 0.39 1.1632 0.8842 2075398 Maybridge3_000418 Cn1nc(OC(C)(C)C(=O)Nc2ccc(Cl)cc2Cl)cc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C23 mock treatment 1141073.0 371000.0 0.79 866218.0 139000.0 0.32 0.7802 0.9201 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 C24 mock treatment 517189.0 -253000.0 -0.54 445941.0 -281000.0 -0.64 -0.8306 -0.9962 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D01 compound treatment 496754.0 -273000.0 -0.58 487549.0 -239000.0 -0.54 -0.7944 -0.9995 1536821 Maybridge3_000419 Nc1nc(cs1)c2ccc3NC(=O)CCc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D02 compound treatment 870327.0 100000.0 0.21 692043.0 -34800.0 -0.08 0.0944 0.4158 2075399 Maybridge3_000420 OC(=O)/C(=C/C(=O)c1ccccc1)/O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D03 compound treatment 1088184.0 318000.0 0.67 1191520.0 465000.0 1.06 1.2239 0.9765 2075400 Maybridge3_000421 COC(=O)/C(=C\Nc1ccc(Sc2ccc(Cl)cc2)nc1)/NC(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D04 compound treatment 1119037.0 349000.0 0.74 1046438.0 320000.0 0.73 1.0369 1.0 1031898 Maybridge3_000422 CC1(C)OCC(O1)C(O)C(O)C2COC(C)(C)O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D05 compound treatment 1146236.0 376000.0 0.8 1113085.0 386000.0 0.88 1.1849 0.9988 1325167 Maybridge3_000423 CN1C2CCC1CC(C2)NC(=O)c3c(F)cccc3F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D06 compound treatment 1343313.0 573000.0 1.22 1051579.0 325000.0 0.74 1.3814 0.9714 1092418 Maybridge3_000424 OCc1ccccc1Sc2ccccc2CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D07 compound treatment 1253966.0 484000.0 1.03 1024691.0 298000.0 0.68 1.2042 0.9797 1360357 Maybridge3_000425 Cc1cc(=O)oc2c(CC=C)c(O)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D08 compound treatment 1128046.0 358000.0 0.76 995124.0 268000.0 0.61 0.968 0.9941 1038220 Maybridge3_000426 Oc1ccc(cc1)C(=O)Cc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D09 compound treatment 1167622.0 398000.0 0.84 1067750.0 341000.0 0.77 1.144 0.9991 2075401 Maybridge3_000427 COc1cccc(NC(=O)C(C)(C)C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D10 compound treatment 1245562.0 476000.0 1.01 1119407.0 393000.0 0.89 1.3439 0.9982 2075402 Maybridge3_000428 C/C(=C/1\N=C(OC1=O)c2ccccc2)/Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D11 compound treatment 1235764.0 466000.0 0.99 1013141.0 286000.0 0.65 1.1584 0.9795 2075403 Maybridge3_000429 c1cc(sc1c2ccccn2)c3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D12 compound treatment 1339406.0 569000.0 1.21 1506482.0 780000.0 1.77 2.1069 0.9825 2075404 Maybridge3_000430 CC(CC(=O)c1cccs1)C(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D13 compound treatment 1370005.0 600000.0 1.27 1637589.0 911000.0 2.07 2.3635 0.9726 1537471 Maybridge3_000431 Oc1c(Cc2ccccc2)c(=O)n3CCCc4cccc1c43 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D14 compound treatment 1465235.0 695000.0 1.47 1300345.0 573000.0 1.3 1.9641 0.9981 2075405 Maybridge3_000432 CC(C)OC(=O)c1cccc2-c3ccccc3C(=O)c21 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D15 compound treatment 1386963.0 617000.0 1.31 1080671.0 354000.0 0.8 1.4936 0.9727 2075406 Maybridge3_000433 Fc1ccc(cc1)C(=O)/C=C/S(=O)(=O)c2ccc(Br)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D16 compound treatment 1431182.0 661000.0 1.4 1164445.0 438000.0 0.99 1.6946 0.9859 2075407 Maybridge3_000434 CCCC(=O)Oc1c[nH]c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D17 compound treatment 1412119.0 642000.0 1.36 1010489.0 284000.0 0.64 1.4185 0.9417 1272565 Maybridge3_000435 CNC(=O)c1ccccc1Sc2ccc(Cl)cc2C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D18 compound treatment 1330500.0 560000.0 1.19 1427085.0 700000.0 1.59 1.9659 0.9896 1116545 Maybridge3_000436 CC(N)C(=O)OCc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D19 compound treatment 1258785.0 489000.0 1.04 1135361.0 408000.0 0.93 1.3894 0.9985 1407680 Maybridge3_000437 OCCc1ccccc1S(=O)c2ccccc2C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D20 compound treatment 1212411.0 442000.0 0.94 1145585.0 419000.0 0.95 1.3363 1.0 1488771 Maybridge3_000438 Nc1ccc(Oc2cccc(Oc3ccc(N)cc3)c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D21 compound treatment 1202794.0 433000.0 0.92 1067093.0 340000.0 0.77 1.1957 0.9964 1095526 Maybridge3_000439 OC1C=COC2COC(OC12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D22 compound treatment 919232.0 149000.0 0.32 996908.0 270000.0 0.61 0.6578 0.9525 2075408 Maybridge3_000440 CC1(C)NC(C)(C)C(=C1)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D23 mock treatment 1127658.0 358000.0 0.76 1022463.0 296000.0 0.67 1.0113 0.9982 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 D24 mock treatment 511061.0 -259000.0 -0.55 493870.0 -233000.0 -0.53 -0.7628 -0.9998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E01 compound treatment 620941.0 -149000.0 -0.32 622366.0 -105000.0 -0.24 -0.3915 -0.9901 1396970 Maybridge3_000441 CC1CCN(CC1)c2ccc(nn2)n3nc(C)cc3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E02 compound treatment 1032843.0 263000.0 0.56 821727.0 94800.0 0.22 0.5465 0.9146 2075409 Maybridge3_000442 O=C(CSc1ssc(=S)c1c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E03 compound treatment 1047353.0 277000.0 0.59 1018834.0 292000.0 0.66 0.8851 0.9982 1322883 Maybridge3_000443 CC(Sc1ncccc1C(=O)O)c2cc(C)ccc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E04 compound treatment 1153035.0 383000.0 0.81 1006005.0 279000.0 0.63 1.0229 0.9926 1644141 Maybridge3_000444 CN(C)C=C=C(O)c1ccccc1C(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E05 compound treatment 1081108.0 311000.0 0.66 1014038.0 287000.0 0.65 0.928 1.0 2075410 Maybridge3_000445 CCCc1cc(O)nc(SCC(=O)Nc2cc(Cl)cc(Cl)c2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E06 compound treatment 1046230.0 276000.0 0.59 1089507.0 363000.0 0.82 0.997 0.986 2075411 Maybridge3_000446 CC(=O)OCCS(=O)(=O)c1ccc(cn1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E07 compound treatment 984772.0 215000.0 0.46 1104927.0 378000.0 0.86 0.9297 0.9559 2075412 Maybridge3_000447 Cc1cc(=O)oc2n(C)nc(c12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E08 compound treatment 1115140.0 345000.0 0.73 1185281.0 458000.0 1.04 1.2543 0.985 1691409 Maybridge3_000448 COC(=O)CNC(=O)c1cccnc1SC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E09 compound treatment 1092099.0 322000.0 0.68 1153709.0 427000.0 0.97 1.169 0.9852 1455911 Maybridge3_000449 Cc1nn(nc1C(=O)Oc2ccc(CC#N)cc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E10 compound treatment 1144001.0 374000.0 0.79 1254417.0 528000.0 1.2 1.4087 0.9798 1176197 Maybridge3_000450 COC(=O)CNC(=O)c1cccnc1Oc2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E11 compound treatment 1072930.0 303000.0 0.64 1416423.0 690000.0 1.57 1.5626 0.9224 2075413 Maybridge3_000451 Cc1ccc(Sc2ccc(N)cn2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E12 compound treatment 1501613.0 732000.0 1.55 1248336.0 521000.0 1.19 1.935 0.9912 2075414 Maybridge3_000452 Cc1cc(OCC(=O)c2ccc(cc2)C(F)(F)F)n3cnnc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E13 compound treatment 1362504.0 593000.0 1.26 1323702.0 597000.0 1.36 1.8476 0.9993 1231742 Maybridge3_000453 N#CCc1cccc(OCc2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E14 compound treatment 1315920.0 546000.0 1.16 1148103.0 421000.0 0.96 1.4955 0.9956 2075415 Maybridge3_000454 CSc1nc(nc(Nc2ccccc2)c1C#N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E15 compound treatment 1214516.0 445000.0 0.94 1157040.0 430000.0 0.98 1.3579 0.9998 1386414 Maybridge3_000455 CSc1nnc(SC)n1CCNS(=O)(=O)c2cccc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E16 compound treatment 1243944.0 474000.0 1.0 1068671.0 342000.0 0.78 1.2599 0.9919 2075416 Maybridge3_000456 Clc1ccc(SCCOC(=O)c2cccc(Cl)c2)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E17 compound treatment 1170319.0 400000.0 0.85 1022638.0 296000.0 0.67 1.0756 0.9934 2075417 Maybridge3_000457 Cc1cc(ccc1Cl)c2csc(=S)n2Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E18 compound treatment 1069343.0 299000.0 0.63 1098978.0 372000.0 0.85 1.0469 0.99 2075418 Maybridge3_000458 Cc1cc(cc(n1)S(=O)(=O)CCOC(=O)c2cccc(Cl)c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E19 compound treatment 1100603.0 331000.0 0.7 1146824.0 420000.0 0.95 1.1707 0.9884 2075419 Maybridge3_000459 N/C(=N\O)/CC(=O)Nc1ccc(F)c(F)c1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E20 compound treatment 1135905.0 366000.0 0.78 963941.0 237000.0 0.54 0.9296 0.9842 1540377 Maybridge3_000460 O=C(CSc1ccccc1)c2ccc3NC(=O)CCc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E21 compound treatment 1168252.0 398000.0 0.84 1032131.0 305000.0 0.69 1.0877 0.9953 2075420 Maybridge3_000461 CSC1=C(C(=SS1)SC)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E22 compound treatment 986394.0 216000.0 0.46 915346.0 188000.0 0.43 0.6274 0.9994 2075421 Maybridge3_000462 Cn1nc(OCC(=O)O)cc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E23 mock treatment 755835.0 -14200.0 -0.03 729737.0 2850.0 0.01 -0.0167 -0.542 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 E24 mock treatment 589660.0 -180000.0 -0.38 539355.0 -188000.0 -0.43 -0.5718 -0.9985 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F01 compound treatment 673588.0 -96400.0 -0.2 860856.0 134000.0 0.3 0.0708 0.1931 2075422 Maybridge3_000463 O/N=C/Nc1nc(cs1)c2ccc3NC(=O)CCc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F02 compound treatment 1013428.0 243000.0 0.52 911601.0 185000.0 0.42 0.6619 0.9948 1508220 Maybridge3_000464 Oc1c(c2ccccc2)c(=O)[nH]c3cc(F)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F03 compound treatment 975054.0 205000.0 0.43 891960.0 165000.0 0.38 0.5728 0.9973 2075423 Maybridge3_000465 FC(F)(F)c1cc(Br)c2[nH]c(=O)c(=O)[nH]c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F04 compound treatment 1083766.0 314000.0 0.67 1137479.0 411000.0 0.93 1.1304 0.9862 2075424 Maybridge3_000466 CC(C)SC1OC(CO)C(O)C(O)C1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F05 compound treatment 1028296.0 258000.0 0.55 1109351.0 382000.0 0.87 1.0021 0.9751 1273132 Maybridge3_000467 COc1ccccc1CC(=O)NC2CC3CCC(C2)N3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F06 compound treatment 1333803.0 564000.0 1.2 1297263.0 570000.0 1.3 1.7621 0.9992 2075425 Maybridge3_000468 CC(=O)Nc1ccccc1OCCOc2ccccc2NC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F07 compound treatment 1214056.0 444000.0 0.94 1316598.0 590000.0 1.34 1.6137 0.985 1315554 Maybridge3_000469 CCCc1cc(=O)c2c(O)cccc2o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F08 compound treatment 1097783.0 328000.0 0.69 931612.0 205000.0 0.47 0.8205 0.981 1133392 Maybridge3_000470 O=c1c(Cc2ccccc2)coc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F09 compound treatment 1025167.0 255000.0 0.54 960446.0 234000.0 0.53 0.758 1.0 1004558 Maybridge3_000471 CN(C)C(c1ccccc1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F10 compound treatment 1236562.0 467000.0 0.99 1220873.0 494000.0 1.12 1.4935 0.998 2075426 Maybridge3_000472 CC1CCCC1/C(=N/O)/c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F11 compound treatment 1614473.0 844000.0 1.79 1236998.0 510000.0 1.16 2.086 0.9779 1635865 Maybridge3_000473 OC(=O)CCCc1ccc2OCOc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F12 compound treatment 1552335.0 782000.0 1.66 1113625.0 387000.0 0.88 1.7945 0.9559 1600318 Maybridge3_000474 CCOC(=O)COc1ccccc1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F13 compound treatment 1259330.0 489000.0 1.04 1046236.0 319000.0 0.73 1.2469 0.9848 1026021 Maybridge3_000475 Cc1nc2ccccc2c(=O)n1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F14 compound treatment 1155016.0 385000.0 0.82 1524364.0 797000.0 1.81 1.8592 0.935 1081820 Maybridge3_000476 CC(C)NC(=O)Oc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F15 compound treatment 1156409.0 386000.0 0.82 1113794.0 387000.0 0.88 1.2012 0.9994 1476519 Maybridge3_000477 CNC(=O)c1cccc2cccc(Sc3ccccc3C(=O)O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F16 compound treatment 1218152.0 448000.0 0.95 1215965.0 489000.0 1.11 1.4581 0.9969 1494580 Maybridge3_000478 Fc1ccc2[nH]c3CCN(Cc3c2c1)C(=O)C4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F17 compound treatment 1000690.0 231000.0 0.49 1124196.0 397000.0 0.9 0.9845 0.9585 1725347 Maybridge3_000479 OC(=O)CCSc1ccccc1C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F18 compound treatment 1095399.0 325000.0 0.69 1103416.0 377000.0 0.86 1.0931 0.9943 1051989 Maybridge3_000480 Fc1ccc(cc1)c2cc(=O)c3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F19 compound treatment 1076455.0 306000.0 0.65 1157839.0 431000.0 0.98 1.1522 0.9801 1534976 Maybridge3_000481 CC(=O)N1Cc2ccccc2S31OC(=O)c4ccccc43 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F20 compound treatment 1086109.0 316000.0 0.67 1054861.0 328000.0 0.75 1.0011 0.9986 1570526 Maybridge3_000482 COC(=O)C1=C(N)CCCC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F21 compound treatment 1111915.0 342000.0 0.72 1111089.0 384000.0 0.87 1.1302 0.9957 2075427 Maybridge3_000483 CC(=O)NC(c1ccc(Cl)cc1)n2ccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F22 compound treatment 907759.0 138000.0 0.29 997884.0 271000.0 0.62 0.6422 0.9418 1077803 Maybridge3_000484 COc1cc(CC(=O)O)ccc1OCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F23 mock treatment 673436.0 -96600.0 -0.2 915224.0 188000.0 0.43 0.158 0.333 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 F24 mock treatment 606616.0 -163000.0 -0.35 506034.0 -221000.0 -0.5 -0.6 -0.9836 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G01 compound treatment 755405.0 -14600.0 -0.03 1045301.0 318000.0 0.72 0.49 0.6763 2075428 Maybridge3_000485 CC1CN(CC(C)O1)c2ccc(nn2)n3nc(C)cc3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G02 compound treatment 940081.0 170000.0 0.36 1109283.0 382000.0 0.87 0.8697 0.924 2075429 Maybridge3_000486 Cc1cc(ccc1Cl)C(=O)CSc2c(F)c(F)c(C(=O)O)c(F)c2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G03 compound treatment 1053656.0 284000.0 0.6 1153165.0 426000.0 0.97 1.1105 0.9737 1376755 Maybridge3_000487 CSc1ncccc1C(=O)NC(C)(C#N)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G04 compound treatment 959687.0 190000.0 0.4 1054607.0 328000.0 0.75 0.8112 0.9581 1363604 Maybridge3_000488 Nc1ncccc1OCc2ccc(Cl)c(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G05 compound treatment 1095936.0 326000.0 0.69 1327934.0 601000.0 1.37 1.4549 0.9501 2075430 Maybridge3_000489 FC(F)(F)c1cccc(c1)C(=O)Nc2ccccc2C(=O)NC3CCCCNC3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G06 compound treatment 1124273.0 354000.0 0.75 1739384.0 1010000.0 2.3 2.1588 0.8916 1142600 Maybridge3_000490 CCOC(=O)c1cnc2c(F)ccc(F)c2c1Oc3cncc(Cl)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G07 compound treatment 1189085.0 419000.0 0.89 1683959.0 957000.0 2.18 2.1669 0.9219 2075431 Maybridge3_000491 NS(=O)(=O)c1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G08 compound treatment 1188008.0 418000.0 0.89 1309848.0 583000.0 1.33 1.5638 0.9808 1303519 Maybridge3_000492 OC(=O)CNC(=O)c1cccnc1Oc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G09 compound treatment 1249579.0 480000.0 1.02 1549829.0 823000.0 1.87 2.0419 0.9589 1181739 Maybridge3_000493 Clc1c(sc2ccccc12)C(=O)Oc3ccc(CC#N)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G10 compound treatment 1013093.0 243000.0 0.52 1393147.0 666000.0 1.51 1.4355 0.8972 1627842 Maybridge3_000494 COC(=O)CNC(=O)c1cccnc1Oc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G11 compound treatment 1122738.0 353000.0 0.75 1711435.0 985000.0 2.24 2.1116 0.8947 1548800 Maybridge3_000495 CC(C)(C)c1ccc(cc1)C(=O)Nc2ccc(Oc3cccnc3)nc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G12 compound treatment 1202311.0 432000.0 0.92 1627542.0 901000.0 2.05 2.096 0.9343 2075432 Maybridge3_000496 OC(=O)CNC(=O)c1ccccc1N(CC=C)C(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G13 compound treatment 1250252.0 480000.0 1.02 1489462.0 763000.0 1.73 1.9459 0.9678 1461087 Maybridge3_000497 Cc1ccc(C)n1c2ncccc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G14 compound treatment 1151417.0 381000.0 0.81 1697419.0 971000.0 2.21 2.132 0.9072 2075433 Maybridge3_000498 CSc1nc(C)nc(Nc2ccccc2)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G15 compound treatment 1291694.0 522000.0 1.11 1716191.0 989000.0 2.25 2.3725 0.9466 1218801 Maybridge3_000499 CCSc1ncccc1C(=O)Oc2cc(C)nn2c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G16 compound treatment 1197624.0 428000.0 0.91 1711314.0 984000.0 2.24 2.2236 0.9208 2075434 Maybridge3_000500 CN(C)c1nc(nc(Nc2cccc(c2)C(F)(F)F)c1C#N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G17 compound treatment 1130821.0 361000.0 0.76 1359601.0 633000.0 1.44 1.5581 0.9563 2075435 Maybridge3_000501 FC(F)(F)c1ccc(cc1)C(=O)Oc2cccc3[nH]ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G18 compound treatment 1131870.0 362000.0 0.77 1217415.0 491000.0 1.12 1.331 0.9833 1668703 Maybridge3_000502 CCOC(=O)c1c(C)c(C#N)c(NC(=O)C(C)(C)C)n1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G19 compound treatment 1085941.0 316000.0 0.67 1186080.0 459000.0 1.04 1.2118 0.977 2075436 Maybridge3_000503 O/N=C/Nc1ncc(cc1Cl)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G20 compound treatment 951950.0 182000.0 0.39 1187416.0 461000.0 1.05 1.0131 0.9079 1419348 Maybridge3_000504 CC(C)(C)SCC(=O)c1ccc2NC(=O)CCc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G21 compound treatment 979109.0 209000.0 0.44 1284633.0 558000.0 1.27 1.2101 0.9008 2075437 Maybridge3_000505 CS(=O)(=O)N(Cc1ccc(Cl)cc1)c2ncc(cc2Cl)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G22 compound treatment 951238.0 181000.0 0.38 1056304.0 329000.0 0.75 0.8013 0.9519 2075438 Maybridge3_000506 Cn1nc(OCC(=O)Nc2ccc(Cl)cc2Cl)cc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G23 mock treatment 897855.0 128000.0 0.27 927859.0 201000.0 0.46 0.5148 0.9689 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 G24 mock treatment 581216.0 -189000.0 -0.4 622686.0 -104000.0 -0.24 -0.4505 -0.9687 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H01 compound treatment 699252.0 -70700.0 -0.15 910766.0 184000.0 0.42 0.1896 0.4268 1528340 Maybridge3_000507 OCc1ccc(OCc2ccc(F)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H02 compound treatment 1191685.0 422000.0 0.89 1313744.0 587000.0 1.33 1.5756 0.981 1058115 Maybridge3_000508 C(N1CCCCC1)n2c3ccccc3c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H03 compound treatment 998732.0 229000.0 0.48 1170119.0 443000.0 1.01 1.0554 0.9438 1676832 Maybridge3_000509 OC(=O)CC(C(=O)NCc1ccccc1)C2=CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H04 compound treatment 1171665.0 402000.0 0.85 1152634.0 426000.0 0.97 1.2866 0.998 1087972 Maybridge3_000510 OCC1OC(Sc2ccccc2)C(O)C(O)C1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H05 compound treatment 1137218.0 367000.0 0.78 1254952.0 528000.0 1.2 1.3994 0.978 1066281 Maybridge3_000511 c1ccc(cc1)c2cccc(n2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H06 compound treatment 1394300.0 624000.0 1.32 1918693.0 1190000.0 2.71 2.8518 0.9457 2075439 Maybridge3_000512 CC1(C)SC(NC1C(=O)O)c2ccc(Cl)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H07 compound treatment 1266870.0 497000.0 1.05 1729422.0 1000000.0 2.28 2.3565 0.9385 1255440 Maybridge3_000513 CCCc1cc(=O)c2c(O)ccc(OC)c2o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H08 compound treatment 1416829.0 647000.0 1.37 1843369.0 1120000.0 2.54 2.7645 0.9582 1220272 Maybridge3_000514 O=C1C(COc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H09 compound treatment 1538500.0 768000.0 1.63 1857562.0 1130000.0 2.57 2.9697 0.9758 1740369 Maybridge3_000515 OCC1c2ccccc2Oc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H10 compound treatment 1454018.0 684000.0 1.45 1693687.0 967000.0 2.2 2.5796 0.9796 1408710 Maybridge3_000516 COC(=O)C(CO)NS(=O)(=O)c1ccc(C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H11 compound treatment 1296529.0 527000.0 1.12 1972523.0 1250000.0 2.83 2.7918 0.9171 1524491 Maybridge3_000517 CC(=O)Nc1ccc-2c(CCc3ccccc32)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H12 compound treatment 1504925.0 735000.0 1.56 1837640.0 1110000.0 2.53 2.8874 0.9731 2075440 Maybridge3_000518 CC1(C)CN=C(Nc2ccc(F)c(Cl)c2)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H13 compound treatment 1776820.0 1010000.0 2.13 1684827.0 958000.0 2.18 3.0493 0.9999 1072271 Maybridge3_000519 CC(=O)Nc1ccc(CC#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H14 compound treatment 1481637.0 712000.0 1.51 1908987.0 1180000.0 2.69 2.9672 0.9627 1064797 Maybridge3_000520 O=C(NC1CCCCC1)Oc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H15 compound treatment 1644419.0 874000.0 1.85 1122049.0 395000.0 0.9 1.9461 0.9447 1330529 Maybridge3_000521 CNC(=O)c1cccc2cccc(Sc3ccccc3C(=O)OC)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H16 compound treatment 1436725.0 667000.0 1.41 1321810.0 595000.0 1.35 1.9559 0.9998 1425252 Maybridge3_000522 Cc1nnsc1C(=O)N2CCc3[nH]c4ccc(F)cc4c3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H17 compound treatment 1523593.0 754000.0 1.6 1034459.0 308000.0 0.7 1.6241 0.9313 1731122 Maybridge3_000523 CCOC(=O)c1ccccc1Sc2ccccc2C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H18 compound treatment 1420075.0 650000.0 1.38 1817075.0 1090000.0 2.48 2.7271 0.9616 2075441 Maybridge3_000524 NC1=C(C#N)C(C(=C(N)S1)C#N)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H19 compound treatment 1274947.0 505000.0 1.07 1647799.0 921000.0 2.09 2.2374 0.9515 2075442 Maybridge3_000525 CN1[S+](c2ccccc2C(=O)O)c3cccc4cccc(C1=O)c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H20 compound treatment 1006454.0 236000.0 0.5 1438206.0 711000.0 1.62 1.498 0.8848 1741501 Maybridge3_000526 OC(=O)c1ncccc1C(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H21 compound treatment 988177.0 218000.0 0.46 1380353.0 653000.0 1.49 1.3776 0.8853 1081833 Maybridge3_000527 COC(=S)Nc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H22 compound treatment 1107933.0 338000.0 0.72 1188388.0 462000.0 1.05 1.2485 0.9827 1016602 Maybridge3_000528 C1CN(CCO1)c2cc(nc3ccccc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H23 mock treatment 1189326.0 419000.0 0.89 1153087.0 426000.0 0.97 1.3138 0.9991 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 H24 mock treatment 641277.0 -129000.0 -0.27 641651.0 -85200.0 -0.19 -0.33 -0.9859 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I01 compound treatment 1184327.0 414000.0 0.88 1117555.0 391000.0 0.89 1.2491 1.0 2075443 Maybridge3_000529 Cc1cc(C)n(n1)c2ccc(SCc3ccc(Cl)cc3)nn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I02 compound treatment 1147359.0 377000.0 0.8 1136249.0 409000.0 0.93 1.2238 0.9972 2075444 Maybridge3_000530 FC(F)(F)Oc1ccc(N/C=C(\C#N)/c2nc3ccccc3[nH]2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I03 compound treatment 1098714.0 329000.0 0.7 1180560.0 454000.0 1.03 1.2221 0.9818 2075445 Maybridge3_000531 Cc1cc(SCc2n[nH]c3oc(=O)cc(C)c23)c(C)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I04 compound treatment 1091270.0 321000.0 0.68 1272521.0 546000.0 1.24 1.3588 0.9601 2075446 Maybridge3_000532 COC(=O)CSc1nnc(SC)n1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I05 compound treatment 1032008.0 262000.0 0.56 1349797.0 623000.0 1.42 1.3942 0.9165 1695135 Maybridge3_000533 CCCc1cc(OC(=O)c2cccnc2Oc3ccccc3)n(C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I06 compound treatment 1506559.0 737000.0 1.56 1381412.0 655000.0 1.49 2.1564 0.9997 1325490 Maybridge3_000534 COc1ccc(Oc2ccc(NC(=O)Cc3cccs3)cn2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I07 compound treatment 1424750.0 655000.0 1.39 1338515.0 612000.0 1.39 1.9648 1.0 1625906 Maybridge3_000535 Clc1ccc(Cl)c(Oc2ccccc2NC(=O)CC#N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I08 compound treatment 1584161.0 814000.0 1.73 1449186.0 722000.0 1.64 2.3817 0.9997 2075447 Maybridge3_000536 OC(=O)CSc1ccc(F)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I09 compound treatment 1616861.0 847000.0 1.8 1395785.0 669000.0 1.52 2.3448 0.9966 2075448 Maybridge3_000537 Clc1ccc(OC(=O)NC(=O)c2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I10 compound treatment 1578151.0 808000.0 1.71 1498977.0 772000.0 1.76 2.4527 0.9999 1187652 Maybridge3_000538 COc1ccc(OC)c(SCC(=O)O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I11 compound treatment 1116362.0 346000.0 0.73 1506404.0 780000.0 1.77 1.7724 0.9239 2075449 Maybridge3_000539 FC(F)(F)c1ccc(cc1)C(=O)Nc2ccc(Oc3cccnc3)nc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I12 compound treatment 1254461.0 484000.0 1.03 1552177.0 825000.0 1.88 2.053 0.9598 2075450 Maybridge3_000540 CSc1nc(C)[nH]c(=O)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I13 compound treatment 1668016.0 898000.0 1.9 1355570.0 629000.0 1.43 2.3569 0.99 2075451 Maybridge3_000541 Clc1cncc(OC(=O)c2cc3ccccc3s2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I14 compound treatment 1497915.0 728000.0 1.54 1335091.0 608000.0 1.38 2.0689 0.9985 2075452 Maybridge3_000542 Clc1cccc(c1)C(=O)OCCSc2ncccc2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I15 compound treatment 1085062.0 315000.0 0.67 1519183.0 792000.0 1.8 1.746 0.9088 2075453 Maybridge3_000543 Cc1cc(OC(=O)c2ccccc2)n(n1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I16 compound treatment 1316794.0 547000.0 1.16 1428259.0 701000.0 1.59 1.9472 0.9877 2075454 Maybridge3_000544 CSc1nc(C)nc(N(C)C)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I17 compound treatment 1409230.0 639000.0 1.36 1448962.0 722000.0 1.64 2.1191 0.9955 1382015 Maybridge3_000545 Cc1ccc(cc1)C(=O)Oc2cccc3[nH]ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I18 compound treatment 1224904.0 455000.0 0.96 1772046.0 1050000.0 2.38 2.3622 0.9211 1277053 Maybridge3_000546 NC(=O)c1ccc(cc1)c2ccc(cc2)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I19 compound treatment 1254730.0 485000.0 1.03 1481207.0 754000.0 1.71 1.9393 0.97 2075455 Maybridge3_000547 FC(F)(F)c1ccc(nc1)S(=O)(=O)CCNC(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I20 compound treatment 1149604.0 380000.0 0.8 1329733.0 603000.0 1.37 1.5382 0.9678 1327270 Maybridge3_000548 Cc1nc(cs1)c2cc(C#N)c(NCc3ccccc3)nc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I21 compound treatment 1081385.0 311000.0 0.66 1425624.0 699000.0 1.59 1.5901 0.9243 2075456 Maybridge3_000549 FC(F)(F)c1ccc(nc1)S(=O)(=O)CC(=O)Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I22 compound treatment 1229403.0 459000.0 0.97 1235857.0 509000.0 1.16 1.5069 0.9963 2075457 Maybridge3_000550 Cn1nc(OCC(=O)NC(C)(C)C)cc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I23 mock treatment 1218236.0 448000.0 0.95 1181053.0 454000.0 1.03 1.4021 0.9991 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 I24 mock treatment 771185.0 1180.0 0.0 583169.0 -144000.0 -0.33 -0.2293 -0.7017 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J01 compound treatment 942688.0 173000.0 0.37 1068420.0 342000.0 0.78 0.8079 0.9411 1256256 Maybridge3_000551 Cc1cc(Cl)ccc1Oc2ncccc2N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J02 compound treatment 1218240.0 448000.0 0.95 1124763.0 398000.0 0.9 1.3116 0.9997 2075458 Maybridge3_000552 CC(C)n1c2ccccc2c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J03 compound treatment 1117587.0 348000.0 0.74 1161857.0 435000.0 0.99 1.2203 0.9895 1244194 Maybridge3_000553 CC(=CC(=O)ON1C(=O)C2C3OC(C=C3)C2C1=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J04 compound treatment 1236241.0 466000.0 0.99 1211888.0 485000.0 1.1 1.4786 0.9985 2075459 Maybridge3_000554 COc1ccc(cc1)C(=O)/C=C/Nc2ccccc2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J05 compound treatment 1260776.0 491000.0 1.04 1316680.0 590000.0 1.34 1.6839 0.9921 2075460 Maybridge3_000555 COc1cc(CCC(C)NCc2ccccc2)ccc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J06 compound treatment 1625616.0 856000.0 1.81 1528247.0 801000.0 1.82 2.5709 1.0 2075461 Maybridge3_000556 c1ccc(cc1)c2cccnn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J07 compound treatment 1452673.0 683000.0 1.45 1476300.0 749000.0 1.7 2.2281 0.9967 1553196 Maybridge3_000557 CCCc1c(N)ccc2c(=O)cc(oc12)C(=O)OCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J08 compound treatment 1448073.0 678000.0 1.44 1472453.0 746000.0 1.7 2.2151 0.9966 1607994 Maybridge3_000558 COc1ccccc1c2coc3ccccc3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J09 compound treatment 1706369.0 936000.0 1.99 1591175.0 864000.0 1.97 2.7931 1.0 1541139 Maybridge3_000559 O=C(Oc1cccnc1)C2c3ccccc3Oc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J10 compound treatment 1823553.0 1050000.0 2.23 1438709.0 712000.0 1.62 2.7237 0.9875 1002178 Maybridge3_000560 CCOC(=O)C1CC(=O)C(CC1=O)C(=O)OCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J11 compound treatment 1638876.0 869000.0 1.84 1372255.0 645000.0 1.47 2.34 0.9937 2075462 Maybridge3_000561 COC(=O)Cc1nc(oc1C)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J12 compound treatment 1613658.0 844000.0 1.79 1544925.0 818000.0 1.86 2.5798 0.9998 2075463 Maybridge3_000562 Cc1ccc(SC#N)c(N)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J13 compound treatment 1835291.0 1070000.0 2.26 1470098.0 743000.0 1.69 2.7917 0.9898 2075464 Maybridge3_000563 c1ccc(cc1)c2cnc(nc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J14 compound treatment 1021864.0 252000.0 0.53 1638074.0 911000.0 2.07 1.8424 0.8612 1019721 Maybridge3_000564 COc1ccc(NC(=O)Oc2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J15 compound treatment 1088538.0 319000.0 0.68 1374321.0 647000.0 1.47 1.5183 0.9375 1367336 Maybridge3_000565 CNC(=O)c1ccccc1Sc2cccc3cccc(COC(=O)C)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J16 compound treatment 1479232.0 709000.0 1.5 1351025.0 624000.0 1.42 2.0666 0.9996 1164670 Maybridge3_000566 Cc1[nH]c2ccccc2c1CC#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J17 compound treatment 1718850.0 949000.0 2.01 1390002.0 663000.0 1.51 2.4884 0.9899 1265803 Maybridge3_000567 OCc1cccc2cccc(S(=O)c3ccccc3C(=O)O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J18 compound treatment 1517825.0 748000.0 1.59 1511840.0 785000.0 1.78 2.3829 0.9983 2075465 Maybridge3_000568 CCN(CC)S(=O)(=O)C1CCS(=O)(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J19 compound treatment 1710046.0 940000.0 1.99 1524973.0 798000.0 1.81 2.6922 0.9989 1431098 Maybridge3_000569 CC(=O)NC(=O)c1cccc2cccc(I)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J20 compound treatment 1255448.0 485000.0 1.03 1453796.0 727000.0 1.65 1.8963 0.974 1588875 Maybridge3_000570 Oc1ccc2OC(CC(=O)c2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J21 compound treatment 1079691.0 310000.0 0.66 1421127.0 694000.0 1.58 1.5803 0.9244 1462691 Maybridge3_000571 Oc1ccccc1N2C(=O)c3cccc4cccc(C2=O)c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J22 compound treatment 234558.0 -535000.0 -1.14 220460.0 -506000.0 -1.15 -1.6168 -1.0 1610135 Maybridge3_000572 CN(C)CCNc1cc(nc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J23 mock treatment 1147688.0 378000.0 0.8 930217.0 203000.0 0.46 0.8931 0.9659 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 J24 mock treatment 685727.0 -84300.0 -0.18 559175.0 -168000.0 -0.38 -0.3959 -0.9403 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K01 compound treatment 747990.0 -22000.0 -0.05 886802.0 160000.0 0.36 0.2241 0.6113 2075466 Maybridge3_000573 Cc1cc(C)n(n1)c2ccc(SCC(=O)Nc3ccc(Cl)cc3)nn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K02 compound treatment 1027381.0 257000.0 0.55 1090293.0 363000.0 0.83 0.9701 0.9797 2075467 Maybridge3_000574 FC(F)(F)c1cccc(N/C=C(\C#N)/c2nc3ccccc3[nH]2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K03 compound treatment 976448.0 206000.0 0.44 1216898.0 490000.0 1.11 1.0972 0.9167 1376910 Maybridge3_000575 Cc1cc(=O)oc2n(nc(c3ccccc3)c12)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K04 compound treatment 1077224.0 307000.0 0.65 1157049.0 430000.0 0.98 1.1521 0.9805 2075468 Maybridge3_000576 FC(F)(F)c1ccc(cc1)C(=O)OCCS(=O)(=O)c2ccc(cn2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K05 compound treatment 1020266.0 250000.0 0.53 1247325.0 520000.0 1.18 1.2118 0.9345 1638249 Maybridge3_000577 Cc1cc(C)n(n1)c2ccc(cc2)S(=O)(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K06 compound treatment 1016105.0 246000.0 0.52 1296897.0 570000.0 1.3 1.2853 0.92 1231832 Maybridge3_000578 Clc1cc(Cl)cc(CNC(=O)Cc2cccs2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K07 compound treatment 1164353.0 394000.0 0.84 1468474.0 742000.0 1.69 1.7834 0.9476 2075469 Maybridge3_000579 CSc1ncccc1C(=O)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K08 compound treatment 1084646.0 315000.0 0.67 1263154.0 536000.0 1.22 1.3338 0.9597 2075470 Maybridge3_000580 OC(=O)CSc1cccc(c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K09 compound treatment 1221814.0 452000.0 0.96 1384973.0 658000.0 1.5 1.7353 0.9768 2075471 Maybridge3_000581 Fc1cccc(F)c1OC(=O)NC(=O)c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K10 compound treatment 1147907.0 378000.0 0.8 1546686.0 820000.0 1.86 1.8844 0.9289 2075472 Maybridge3_000582 Cc1cc(OCC(=O)c2cccc(c2)C(F)(F)F)n3cnnc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K11 compound treatment 1535486.0 765000.0 1.62 1381885.0 655000.0 1.49 2.2005 0.9991 2075473 Maybridge3_000583 Clc1ccc(cc1)C(=O)Nc2ccc(Oc3cccnc3)nc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K12 compound treatment 1065447.0 295000.0 0.63 1345803.0 619000.0 1.41 1.4379 0.9335 2075474 Maybridge3_000584 COC(=O)CSc1nc(C)nc(SC)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K13 compound treatment 1311156.0 541000.0 1.15 1373622.0 647000.0 1.47 1.8509 0.9925 2075475 Maybridge3_000585 Clc1cncc(OC(=O)c2cccs2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K14 compound treatment 1501054.0 731000.0 1.55 1648895.0 922000.0 2.1 2.5781 0.989 2075476 Maybridge3_000586 FC(F)(F)c1cccnc1S(=O)(=O)CCOC(=O)c2cccc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K15 compound treatment 1447606.0 678000.0 1.44 1535736.0 809000.0 1.84 2.3161 0.9925 1399454 Maybridge3_000587 COC(=O)c1c(OC)ccc(c1OC)n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K16 compound treatment 1423228.0 653000.0 1.38 1430171.0 703000.0 1.6 2.1098 0.9974 2075477 Maybridge3_000588 COC(=O)C(C)(C)S(=O)(=O)c1ccc(cn1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K17 compound treatment 1311343.0 541000.0 1.15 1505562.0 779000.0 1.77 2.0633 0.978 1203424 Maybridge3_000589 Fc1cccc(F)c1C(=O)Oc2cccc3[nH]ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K18 compound treatment 1408578.0 639000.0 1.35 1910664.0 1180000.0 2.69 2.8603 0.9494 1414362 Maybridge3_000590 CC(=O)Nc1cc(C)ccc1OC(C)(C)C(=O)OC(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K19 compound treatment 1460798.0 691000.0 1.46 1423725.0 697000.0 1.58 2.1558 0.9992 2075478 Maybridge3_000591 Nc1cccnc1Oc2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K20 compound treatment 1390628.0 621000.0 1.32 1330248.0 603000.0 1.37 1.9003 0.9998 1605002 Maybridge3_000592 CCOC(=O)c1[nH]c(Cc2[nH]c(C(=O)OCC)c(C)c2C)c(C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K21 compound treatment 1255991.0 486000.0 1.03 1333321.0 606000.0 1.38 1.7034 0.9897 2075479 Maybridge3_000593 FC(F)(F)c1cccc(c1)S(=O)(=O)N(CCC#N)Cc2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K22 compound treatment 1166542.0 397000.0 0.84 1167599.0 441000.0 1.0 1.3029 0.9962 2075480 Maybridge3_000594 CN(C)C(=O)C(C)(C)Oc1cc(n(C)n1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K23 mock treatment 1060269.0 290000.0 0.62 1073189.0 346000.0 0.79 0.9919 0.9926 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 K24 mock treatment 648499.0 -122000.0 -0.26 521593.0 -205000.0 -0.47 -0.5122 -0.9607 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L01 compound treatment 544479.0 -226000.0 -0.48 832102.0 105000.0 0.24 -0.1689 -0.316 1636894 Maybridge3_000595 Cc1nc(c(o1)c2ccccc2)c3ccc(NC(=O)C(C)(C)C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L02 compound treatment 860974.0 91000.0 0.19 999770.0 273000.0 0.62 0.5751 0.8851 1057689 Maybridge3_000596 OCn1c2ccccc2c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L03 compound treatment 904026.0 134000.0 0.28 1097158.0 370000.0 0.84 0.7962 0.8961 1250886 Maybridge3_000597 Clc1ccc(s1)C(=O)ON2C(=O)C3C4OC(C=C4)C3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L04 compound treatment 1062617.0 293000.0 0.62 1216843.0 490000.0 1.11 1.2263 0.9618 1337528 Maybridge3_000598 CCSc1ncc(c2nnnn2c3ccccc3)c(n1)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L05 compound treatment 997858.0 228000.0 0.48 1252097.0 525000.0 1.19 1.1859 0.9207 2075481 Maybridge3_000599 Cc1oc(nc1CCO)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L06 compound treatment 1148405.0 378000.0 0.8 1565539.0 839000.0 1.91 1.9155 0.926 1416638 Maybridge3_000600 CCCCn1c(=O)cc(O)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L07 compound treatment 1045694.0 276000.0 0.58 1250623.0 524000.0 1.19 1.2553 0.9463 1179929 Maybridge3_000601 COc1ccc(OCCN)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L08 compound treatment 1147737.0 378000.0 0.8 1253618.0 527000.0 1.2 1.413 0.9809 2075482 Maybridge3_000602 COc1ccc(cc1)c2coc3ccccc3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L09 compound treatment 1166056.0 396000.0 0.84 1285499.0 559000.0 1.27 1.4918 0.9798 1077052 Maybridge3_000603 O=C(C(SC#N)c1ccccc1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L10 compound treatment 1187734.0 418000.0 0.89 1456476.0 730000.0 1.66 1.7991 0.9568 1077090 Maybridge3_000604 OC(=O)C1CC2CCC1C=C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L11 compound treatment 1564128.0 794000.0 1.68 1237521.0 511000.0 1.16 2.0113 0.9835 2075483 Maybridge3_000605 O=C(CCC(=O)c1ccccc1)OCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L12 compound treatment 1393616.0 624000.0 1.32 1281609.0 555000.0 1.26 1.8266 0.9997 2075484 Maybridge3_000606 O=c1ccc(no1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L13 compound treatment 1309322.0 539000.0 1.14 1467778.0 741000.0 1.68 1.9995 0.9822 1703544 Maybridge3_000607 O=c1[nH]c2ccccc2c3oc(nc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L14 compound treatment 1738766.0 969000.0 2.05 1353289.0 626000.0 1.42 2.4592 0.984 2075485 Maybridge3_000608 Clc1ccc(OC(=O)NCCc2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L15 compound treatment 1343509.0 574000.0 1.22 1448196.0 721000.0 1.64 2.0193 0.9892 1337655 Maybridge3_000609 CNC(=O)c1ccccc1Sc2cccc3cccc(C(=O)NC)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L16 compound treatment 1323267.0 553000.0 1.17 1372096.0 645000.0 1.47 1.8666 0.9939 2075486 Maybridge3_000610 CSC(=S)Nc1ccc(Br)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L17 compound treatment 1383381.0 613000.0 1.3 1253774.0 527000.0 1.2 1.7665 0.9992 2075487 Maybridge3_000611 COC(=O)c1ccccc1S(=O)c2cccc3cccc(CO)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L18 compound treatment 1653454.0 883000.0 1.87 1259282.0 532000.0 1.21 2.1802 0.9777 2075488 Maybridge3_000612 OC(=O)CSC1CCS(=O)(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L19 compound treatment 1369846.0 600000.0 1.27 1325521.0 599000.0 1.36 1.8616 0.9994 1640133 Maybridge3_000613 COc1ccc(NC(=O)C)c(c1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L20 compound treatment 1181461.0 411000.0 0.87 1106518.0 380000.0 0.86 1.2271 1.0 2075489 Maybridge3_000614 Nc1nnc(Nc2ccc(Cl)cc2)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L21 compound treatment 1244992.0 475000.0 1.01 1075184.0 348000.0 0.79 1.272 0.9929 2075490 Maybridge3_000615 c1c(sc2nc(nnc12)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L22 compound treatment 1259776.0 490000.0 1.04 1059637.0 333000.0 0.76 1.2691 0.9879 1005928 Maybridge3_000616 Cc1ccc(CCC(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L23 mock treatment 1191458.0 421000.0 0.89 872247.0 145000.0 0.33 0.8655 0.9085 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 L24 mock treatment 608762.0 -161000.0 -0.34 596386.0 -130000.0 -0.3 -0.4515 -0.9975 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M01 compound treatment 569209.0 -201000.0 -0.43 845513.0 119000.0 0.27 -0.1103 -0.2189 2075491 Maybridge3_000617 Cn1cc(C(=O)Nc2ccc(F)c(Cl)c2)c(N)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M02 compound treatment 1014532.0 245000.0 0.52 1051597.0 325000.0 0.74 0.8886 0.985 2075492 Maybridge3_000618 CSc1nc2nccc(NC(=O)c3cccc(C)c3)n2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M03 compound treatment 1090394.0 320000.0 0.68 1098417.0 372000.0 0.84 1.0776 0.9942 2075493 Maybridge3_000619 CCCc1cc(=O)oc2n(C)nc(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M04 compound treatment 1044841.0 275000.0 0.58 1156808.0 430000.0 0.98 1.1032 0.9694 2075494 Maybridge3_000620 FC(F)(F)c1ccc(nc1)S(=O)(=O)CCOC(=O)Nc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M05 compound treatment 932198.0 162000.0 0.34 1159155.0 432000.0 0.98 0.9381 0.901 2075495 Maybridge3_000621 Fc1ccc(CNC(=O)CC#N)c(F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M06 compound treatment 950326.0 180000.0 0.38 1160746.0 434000.0 0.99 0.9678 0.9148 1178380 Maybridge3_000622 Fc1ccc(c2ccc(CNC(=O)Cc3cccs3)o2)c(F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M07 compound treatment 1042648.0 273000.0 0.58 1241023.0 514000.0 1.17 1.2353 0.9473 1222852 Maybridge3_000623 O=C1CS(=O)(=O)N(Cc2ccccc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M08 compound treatment 1184203.0 414000.0 0.88 1237950.0 511000.0 1.16 1.4425 0.9905 1529004 Maybridge3_000624 COc1ccc(OC)c(Sc2ncccc2C(=O)O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M09 compound treatment 1175879.0 406000.0 0.86 1294790.0 568000.0 1.29 1.5214 0.9805 2075496 Maybridge3_000625 Oc1ccc(cc1)/C(=C/c2ccc(cc2)C(F)(F)F)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M10 compound treatment 1150439.0 380000.0 0.81 1158375.0 431000.0 0.98 1.264 0.9953 2075497 Maybridge3_000626 CSc1ncccc1C2=N/C(=C\c3ccc(Cl)cc3)/C(=O)O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M11 compound treatment 830253.0 60300.0 0.13 1067613.0 341000.0 0.77 0.6381 0.8127 1507727 Maybridge3_000627 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(Oc3cccnc3)nc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M12 compound treatment 1229739.0 460000.0 0.97 1428017.0 701000.0 1.59 1.8163 0.9721 2075498 Maybridge3_000628 CSc1nc(nc(Sc2ccccc2)c1C#N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M13 compound treatment 1039002.0 269000.0 0.57 1139292.0 412000.0 0.94 1.0662 0.9716 1127265 Maybridge3_000629 Clc1cc(Cl)cc(COc2ccc(CC#N)cc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M14 compound treatment 986736.0 217000.0 0.46 1125696.0 399000.0 0.91 0.966 0.9504 2075499 Maybridge3_000630 CSC1=C(C#N)C(=C(C#N)C#N)NC(=N1)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M15 compound treatment 1033168.0 263000.0 0.56 1072060.0 345000.0 0.78 0.9494 0.986 1645179 Maybridge3_000631 O=C(Nc1nnc(SCC#N)s1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M16 compound treatment 1059682.0 290000.0 0.61 1157625.0 431000.0 0.98 1.1267 0.9747 2075500 Maybridge3_000632 CC(C)(C(=O)Nc1ccccc1)S(=O)(=O)c2ccc(cn2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M17 compound treatment 1067928.0 298000.0 0.63 1102505.0 376000.0 0.85 1.0505 0.989 1582377 Maybridge3_000633 CCOC(=O)c1cc(NC(=O)C)ccc1Oc2cncc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M18 compound treatment 1090852.0 321000.0 0.68 1181717.0 455000.0 1.03 1.2122 0.9793 2075501 Maybridge3_000634 CC(C)(Oc1ccc(C#N)cc1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M19 compound treatment 885414.0 115000.0 0.24 1119402.0 393000.0 0.89 0.804 0.8689 2075502 Maybridge3_000635 Fc1ccc(Oc2ccc(NC(=O)/C=C/c3ccccc3)cn2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M20 compound treatment 1146698.0 377000.0 0.8 1120349.0 393000.0 0.89 1.1972 0.9984 2075503 Maybridge3_000636 CCCC1=C(C(=O)NC1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M21 compound treatment 934884.0 165000.0 0.35 1125501.0 399000.0 0.91 0.888 0.9142 2075504 Maybridge3_000637 CCOC(=O)NC1=Nc2ccccc2NC=C1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M22 compound treatment 1084235.0 314000.0 0.67 1039398.0 313000.0 0.71 0.9735 0.9995 2075505 Maybridge3_000638 Cn1nc(OC(C)(C)C(=O)NC(C)(C)C)cc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M23 mock treatment 1055009.0 285000.0 0.6 939312.0 212000.0 0.48 0.7687 0.9938 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 M24 mock treatment 456780.0 -313000.0 -0.66 561994.0 -165000.0 -0.37 -0.7346 -0.9634 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N01 compound treatment 672134.0 -97900.0 -0.21 799150.0 72300.0 0.16 -0.0305 -0.1154 2075506 Maybridge3_000639 CC(=CC(=O)Oc1ccc(cc1)n2nnnc2SCC=C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N02 compound treatment 1165983.0 396000.0 0.84 1227677.0 501000.0 1.14 1.3987 0.9888 2075507 Maybridge3_000640 C(C1CS1)n2c3ccccc3c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N03 compound treatment 1193009.0 423000.0 0.9 1191321.0 464000.0 1.06 1.3807 0.9967 2075508 Maybridge3_000641 FC(F)(F)Oc1ccc(CON2C(=O)C3C4OC(C=C4)C3C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N04 compound treatment 1266918.0 497000.0 1.05 1204117.0 477000.0 1.09 1.5121 0.9999 2075509 Maybridge3_000642 CCOC(=O)c1c(O)cc(C)[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N05 compound treatment 1268383.0 498000.0 1.06 1031003.0 304000.0 0.69 1.236 0.9789 2075510 Maybridge3_000643 CN1C2CCC1CC(C2)NC(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N06 compound treatment 1479576.0 710000.0 1.5 1217268.0 490000.0 1.11 1.852 0.9891 1447827 Maybridge3_000644 OC(=O)C(=C1C2CC3CC(C2)CC1C3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N07 compound treatment 1197531.0 428000.0 0.91 1068439.0 342000.0 0.78 1.19 0.997 1706281 Maybridge3_000645 CCOC(=O)c1c(C)[nH]c2ccc(OCC=C)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N08 compound treatment 1345293.0 575000.0 1.22 1142866.0 416000.0 0.95 1.5311 0.9921 1203832 Maybridge3_000646 COc1ccc(Nc2nc3ccccc3nc2c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N09 compound treatment 1315008.0 545000.0 1.16 1177909.0 451000.0 1.03 1.5421 0.9982 1034187 Maybridge3_000647 OCc1ccccc1c2ccccc2CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N10 compound treatment 1193741.0 424000.0 0.9 1209707.0 483000.0 1.1 1.4114 0.995 1363311 Maybridge3_000648 CCOc1ccc(cc1)N2Cc3cc(OCC)ccc3N=C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N11 compound treatment 1291713.0 522000.0 1.11 1182488.0 456000.0 1.04 1.5145 0.9995 2075511 Maybridge3_000649 COc1cccc(c1)/C(=C/O)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N12 compound treatment 1415319.0 645000.0 1.37 1138457.0 412000.0 0.94 1.629 0.9828 1698210 Maybridge3_000650 O=C(N1CCOCC1)c2cccc3Cc4ccccc4-c32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N13 compound treatment 1220866.0 451000.0 0.96 1296480.0 570000.0 1.3 1.5916 0.9888 2075512 Maybridge3_000651 O=C1OCC(=C1)Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N14 compound treatment 1198665.0 429000.0 0.91 1137876.0 411000.0 0.93 1.3033 0.9999 1185125 Maybridge3_000652 COc1ccc(OC(=O)NCCc2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N15 compound treatment 1040467.0 270000.0 0.57 1049588.0 323000.0 0.73 0.9242 0.9926 1092424 Maybridge3_000653 CNC(=O)c1ccccc1Sc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N16 compound treatment 1342819.0 573000.0 1.21 1230124.0 503000.0 1.14 1.6677 0.9996 2075513 Maybridge3_000654 CSC(=S)Nc1ccc(NC(=O)C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N17 compound treatment 1199039.0 429000.0 0.91 1026565.0 300000.0 0.68 1.1249 0.9899 1364067 Maybridge3_000655 CNC(=O)c1ccccc1S(=O)c2cccc3cccc(CO)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N18 compound treatment 1279798.0 510000.0 1.08 1111303.0 384000.0 0.87 1.3822 0.9945 1191735 Maybridge3_000656 COc1ccc(NC(CC(=O)C2CC2)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N19 compound treatment 1341329.0 571000.0 1.21 1115331.0 388000.0 0.88 1.4809 0.988 2075514 Maybridge3_000657 Cc1ccc(I)c(c1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N20 compound treatment 1302169.0 532000.0 1.13 1076388.0 350000.0 0.79 1.3596 0.9853 1028615 Maybridge3_000658 Nc1cc(Nc2ccc(Br)cc2)nc(N)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N21 compound treatment 1386269.0 616000.0 1.31 1126595.0 400000.0 0.91 1.5664 0.9843 2075515 Maybridge3_000659 COc1ccc(cc1)c2cc3nnc(nc3s2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N22 compound treatment 1090157.0 320000.0 0.68 1045521.0 319000.0 0.72 0.9922 0.9995 2075516 Maybridge3_000660 CCOC(=O)c1cc(CO)cc(c1)C(=O)OCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N23 mock treatment 988981.0 219000.0 0.46 981189.0 254000.0 0.58 0.7371 0.9941 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 N24 mock treatment 533084.0 -237000.0 -0.5 669041.0 -57800.0 -0.13 -0.4481 -0.8632 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O01 compound treatment 554734.0 -215000.0 -0.46 647657.0 -79200.0 -0.18 -0.4501 -0.9173 1916588 Maybridge3_000661 COC(=O)/C=C/1\Nc2ccccc2NC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O02 compound treatment 825385.0 55400.0 0.12 1178818.0 452000.0 1.03 0.8096 0.7828 2075517 Maybridge3_000662 COC(=O)CS(=O)(=O)c1nccn1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O03 compound treatment 950765.0 181000.0 0.38 1062483.0 336000.0 0.76 0.8105 0.9492 2075518 Maybridge3_000663 CCCc1cc(=O)oc2[nH]nc(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O04 compound treatment 230293.0 -540000.0 -1.14 260144.0 -467000.0 -1.06 -1.5594 -0.9993 1733743 Maybridge3_000664 CC(C)(C)c1cc(cc(c1)C(=O)Nc2cccnc2)C(=O)Nc3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O05 compound treatment 1027080.0 257000.0 0.54 976694.0 250000.0 0.57 0.787 0.9998 2075519 Maybridge3_000665 CN(C(=O)CC#N)c1ccc(F)cc1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O06 compound treatment 1108669.0 339000.0 0.72 1046684.0 320000.0 0.73 1.0218 1.0 1716609 Maybridge3_000666 CCOC(=O)c1cnc2onc(C)c2c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O07 compound treatment 908110.0 138000.0 0.29 1005085.0 278000.0 0.63 0.6543 0.9387 1479341 Maybridge3_000667 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccccc3N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O08 compound treatment 1141633.0 372000.0 0.79 1147722.0 421000.0 0.96 1.2336 0.9953 1483580 Maybridge3_000668 Cc1ccc(Oc2ncccc2C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O09 compound treatment 1092027.0 322000.0 0.68 908840.0 182000.0 0.41 0.7752 0.9712 2075520 Maybridge3_000669 COc1ccc(/C=C(\C#N)/c2ccc(O)cc2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O10 compound treatment 1110146.0 340000.0 0.72 920261.0 193000.0 0.44 0.8208 0.9718 2075521 Maybridge3_000670 CSc1ncccc1C2=N/C(=C\c3ccc(C)cc3)/C(=O)O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O11 compound treatment 956488.0 186000.0 0.4 1075810.0 349000.0 0.79 0.8405 0.9483 1150800 Maybridge3_000671 CC(=O)Nc1ccc(Oc2cccnc2)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O12 compound treatment 848202.0 78200.0 0.17 996328.0 269000.0 0.61 0.5504 0.8673 2075522 Maybridge3_000672 O=C(OCCSc1ccccn1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O13 compound treatment 909731.0 140000.0 0.3 1090123.0 363000.0 0.83 0.7934 0.9043 1018990 Maybridge3_000673 O=C(C1COC(=O)C1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O14 compound treatment 1306028.0 536000.0 1.14 1005429.0 279000.0 0.63 1.2513 0.9619 1473988 Maybridge3_000674 Nc1n(nc2[nH]c(nc(=O)c12)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O15 compound treatment 1061586.0 292000.0 0.62 1033652.0 307000.0 0.7 0.9303 0.9982 1287534 Maybridge3_000675 CC(=O)Nc1nnc(SCC#N)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O16 compound treatment 1212899.0 443000.0 0.94 1054274.0 327000.0 0.74 1.1902 0.9934 1469722 Maybridge3_000676 CCOC(=O)c1c(C)c2c(=O)[nH]cnc2n1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O17 compound treatment 975529.0 206000.0 0.44 878985.0 152000.0 0.35 0.5526 0.9934 2075523 Maybridge3_000677 Cc1ccc(cc1)C(=O)OCCSc2ccc(cn2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O18 compound treatment 1086678.0 317000.0 0.67 960417.0 234000.0 0.53 0.8501 0.9933 1613952 Maybridge3_000678 Cc1[nH]c(=O)c(C#N)cc1c2csc(n2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O19 compound treatment 1147850.0 378000.0 0.8 1035226.0 308000.0 0.7 1.0621 0.9978 2075524 Maybridge3_000679 Fc1ccc(Oc2ncccc2NC(=O)/C=C/c3ccccc3)c(F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O20 compound treatment 1034753.0 265000.0 0.56 1015769.0 289000.0 0.66 0.8613 0.9969 1551430 Maybridge3_000680 CC(=O)N1CC(=C(C#N)C1O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O21 compound treatment 1298219.0 528000.0 1.12 951859.0 225000.0 0.51 1.1535 0.937 1186844 Maybridge3_000681 CCCN(c1ccc(C)cc1)c2nc(=O)c3cccnc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O22 compound treatment 1047813.0 278000.0 0.59 941950.0 215000.0 0.49 0.7622 0.9957 2075525 Maybridge3_000682 Cc1ccc(Oc2ccc(cn2)C(F)(F)F)c3CCCc31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O23 mock treatment 906177.0 136000.0 0.29 921931.0 195000.0 0.44 0.5177 0.9784 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 O24 mock treatment 449748.0 -320000.0 -0.68 510856.0 -216000.0 -0.49 -0.8274 -0.9874 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P01 compound treatment 430071.0 -340000.0 -0.72 471167.0 -256000.0 -0.58 -0.9207 -0.9943 2075526 Maybridge3_000683 Oc1cc(ccn1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P02 compound treatment 609584.0 -160000.0 -0.34 535238.0 -192000.0 -0.44 -0.5486 -0.9925 1151687 Maybridge3_000684 CC(=O)Oc1cc2sc(=O)oc2c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P03 compound treatment 727344.0 -42700.0 -0.09 705292.0 -21600.0 -0.05 -0.0987 -0.9588 1419965 Maybridge3_000685 Fc1cccc(Cl)c1CON2C(=O)C3C4OC(C=C4)C3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P04 compound treatment 869546.0 99500.0 0.21 713436.0 -13400.0 -0.03 0.1276 0.5984 2075527 Maybridge3_000686 CC(=O)Nc1ccc(OCCOc2ccc(NC(=O)C)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P05 compound treatment 865768.0 95800.0 0.2 775283.0 48400.0 0.11 0.2214 0.9586 1690708 Maybridge3_000687 CCOC(=O)c1cc(=O)c2c(O)cccc2o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P06 compound treatment 973236.0 203000.0 0.43 948810.0 222000.0 0.5 0.6614 0.9969 1527724 Maybridge3_000688 CC(C)OC(=O)c1cccc2C(=O)c3ccccc3-c21 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P07 compound treatment 873057.0 103000.0 0.22 868826.0 142000.0 0.32 0.3827 0.982 1338763 Maybridge3_000689 Oc1nc2ccccc2n(c3ccc(Cl)cc3)c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P08 compound treatment 722964.0 -47000.0 -0.1 741551.0 14700.0 0.03 -0.0469 -0.4464 2075528 Maybridge3_000690 CSC1=N/C(=C/c2ccco2)/C(=O)N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P09 compound treatment 847549.0 77500.0 0.16 752713.0 25800.0 0.06 0.1578 0.9038 1009360 Maybridge3_000691 CC(C)C1CCC(C)CC1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P10 compound treatment 735896.0 -34100.0 -0.07 706088.0 -20800.0 -0.05 -0.0846 -0.9788 2075529 Maybridge3_000692 OC1(CCCCC1)c2cccc(F)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P11 compound treatment 823251.0 53200.0 0.11 792198.0 65300.0 0.15 0.1848 0.9908 1138107 Maybridge3_000693 CCN(CC)C(=O)c1cccc2C(=O)c3ccccc3-c21 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P12 compound treatment 779205.0 9200.0 0.02 667758.0 -59100.0 -0.13 -0.0813 -0.5982 1430738 Maybridge3_000694 CCN(CC)C(=O)c1cccc2-c3ccccc3C(=O)c21 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P13 compound treatment 881067.0 111000.0 0.24 703443.0 -23400.0 -0.05 0.1288 0.5336 2075530 Maybridge3_000695 CCc1c(O)c2ccccc2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P14 compound treatment 847985.0 78000.0 0.17 661282.0 -65600.0 -0.15 0.0114 0.0514 1051125 Maybridge3_000696 CNC(=O)Oc1cccc(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P15 compound treatment 982319.0 212000.0 0.45 871735.0 145000.0 0.33 0.5511 0.9882 1656319 Maybridge3_000697 CCNC(=O)c1ccccc1Sc2ccccc2CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P16 compound treatment 950535.0 181000.0 0.38 745522.0 18600.0 0.04 0.3006 0.7806 1286529 Maybridge3_000698 Oc1c(c2ccccc2)c(=O)n(c3ccccc3)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P17 compound treatment 814185.0 44200.0 0.09 807736.0 80900.0 0.18 0.1962 0.9511 1429737 Maybridge3_000699 CNC(=O)c1ccccc1S(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P18 compound treatment 702490.0 -67500.0 -0.14 815553.0 88700.0 0.2 0.0413 0.1672 1600212 Maybridge3_000700 Cc1ccc(NC(CC(=O)C2CC2)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P19 compound treatment 900320.0 130000.0 0.28 981759.0 255000.0 0.58 0.6051 0.9426 1143166 Maybridge3_000701 Oc1cc(=O)n(c2ccccc2)c3CCCCc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P20 compound treatment 1028437.0 258000.0 0.55 905228.0 178000.0 0.41 0.6741 0.989 1066953 Maybridge3_000702 CSc1nc(C(=O)N)c(N)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P21 compound treatment 980952.0 211000.0 0.45 680442.0 -46400.0 -0.11 0.2416 0.5257 2075531 Maybridge3_000703 Clc1ccc(cc1)c2cc3nnc(nc3s2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P22 compound treatment 733301.0 -36700.0 -0.08 668832.0 -58100.0 -0.13 -0.1483 -0.9682 2075532 Maybridge3_000704 CCC(=O)N1C2CC(C=C2)C1(C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P23 mock treatment 566227.0 -204000.0 -0.43 578245.0 -149000.0 -0.34 -0.5444 -0.9926 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1432 P24 mock treatment 418071.0 -352000.0 -0.75 538117.0 -189000.0 -0.43 -0.831 -0.9655 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A01 compound treatment 452436.0 -348000.0 -0.74 497033.0 -218000.0 -0.5 -0.8726 -0.9811 1063882 Maybridge3_000705 OC(C(=O)O)c1cccc(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A02 compound treatment 603891.0 -197000.0 -0.42 507990.0 -207000.0 -0.47 -0.6279 -0.9982 1012545 Maybridge3_000706 O=C(c1ccccc1)c2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A03 compound treatment 694145.0 -107000.0 -0.23 661815.0 -53100.0 -0.12 -0.2453 -0.9569 1340150 Maybridge3_000707 CC(=O)Nc1ccc(O)c(c1)C(=O)CC(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A04 compound treatment 595946.0 -205000.0 -0.43 603001.0 -112000.0 -0.25 -0.4871 -0.9676 2075533 Maybridge3_000708 O=C(CC1S/C(=N/c2ccccc2)/NC1=O)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A05 compound treatment 657407.0 -143000.0 -0.3 612005.0 -103000.0 -0.23 -0.3805 -0.9917 1587589 Maybridge3_000709 O=C(C1CCCCC1)N2CCN(CC2)c3cccc4[nH]ccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A06 compound treatment 694250.0 -107000.0 -0.23 685977.0 -29000.0 -0.07 -0.2063 -0.8768 2075534 Maybridge3_000710 O=C/1Nc2ccccc2\C1=C/c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A07 compound treatment 527519.0 -273000.0 -0.58 519220.0 -196000.0 -0.45 -0.7243 -0.9915 1198441 Maybridge3_000711 COc1ccc(CCNC(=O)c2cccs2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A08 compound treatment 649405.0 -151000.0 -0.32 618136.0 -96800.0 -0.22 -0.3826 -0.9831 1664899 Maybridge3_000712 Cc1cc(C)c(C(=O)O)c2CC(C)(C)C(=O)c21 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A09 compound treatment 637404.0 -163000.0 -0.35 693096.0 -21900.0 -0.05 -0.2801 -0.8003 1156182 Maybridge3_000713 CN1C2CCC1CC(C2)NC(=O)CSc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A10 compound treatment 618159.0 -183000.0 -0.39 696654.0 -18300.0 -0.04 -0.3032 -0.7786 1579963 Maybridge3_000714 Clc1ccc(cc1)C(=O)Nc2ccccc2C(=O)NCc3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A11 compound treatment 610713.0 -190000.0 -0.4 644077.0 -70900.0 -0.16 -0.3989 -0.9191 1650341 Maybridge3_000715 CCOC(=O)c1cc(=O)oc2cc(O)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A12 compound treatment 903206.0 102000.0 0.22 685331.0 -29600.0 -0.07 0.1059 0.4658 2075535 Maybridge3_000716 CN(C)c1ccc(cc1)C2Nc3ccccc3S2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A13 compound treatment 634444.0 -166000.0 -0.35 551714.0 -163000.0 -0.37 -0.5118 -0.9997 1654309 Maybridge3_000717 CC1(CC2(C)CC3(C)C1)CC(CCO)(C2)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A14 compound treatment 687247.0 -114000.0 -0.24 585276.0 -130000.0 -0.29 -0.3787 -0.9949 1563478 Maybridge3_000718 OC(=O)CCC(=O)N1CCCc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A15 compound treatment 698022.0 -103000.0 -0.22 647857.0 -67100.0 -0.15 -0.262 -0.9848 1663621 Maybridge3_000719 CCOC(=O)c1nnc2cc(sc2n1)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A16 compound treatment 644546.0 -156000.0 -0.33 593842.0 -121000.0 -0.28 -0.429 -0.9958 2075536 Maybridge3_000720 COc1ccc(OC)c(c1)C(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A17 compound treatment 592839.0 -208000.0 -0.44 548846.0 -166000.0 -0.38 -0.5788 -0.997 2075537 Maybridge3_000721 CCCOc1cccc(c1)C2CCCCN(C)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A18 compound treatment 569508.0 -231000.0 -0.49 460502.0 -254000.0 -0.58 -0.7558 -0.9966 2075538 Maybridge3_000722 Clc1ccc(cc1)c2noc(CSC3=NCC4CCCC4N3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A19 compound treatment 762612.0 -38200.0 -0.08 587357.0 -128000.0 -0.29 -0.2624 -0.8712 1715439 Maybridge3_000723 CN(CC(=O)Nc1ccccc1)C(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A20 compound treatment 722457.0 -78400.0 -0.17 570020.0 -145000.0 -0.33 -0.3505 -0.9497 1056263 Maybridge3_000724 COc1ccc(cc1)C2C(C#N)(C#N)C2(C#N)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A21 compound treatment 769764.0 -31100.0 -0.07 504349.0 -211000.0 -0.48 -0.3851 -0.7968 1297522 Maybridge3_000725 OC(=O)C1C(C2CCC1CCC2)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A22 compound treatment 669256.0 -132000.0 -0.28 527118.0 -188000.0 -0.43 -0.4992 -0.9787 1429927 Maybridge3_000726 Clc1ccc(cc1)c2nc(CN3CCOCC3)cs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A23 mock treatment 614090.0 -187000.0 -0.4 444366.0 -271000.0 -0.62 -0.7149 -0.9773 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 A24 mock treatment 444511.0 -356000.0 -0.76 389110.0 -326000.0 -0.74 -1.0579 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B01 compound treatment 411978.0 -389000.0 -0.82 517118.0 -198000.0 -0.45 -0.9009 -0.9594 1652436 Maybridge3_000727 Oc1nc(CSc2ccccn2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B02 compound treatment 698139.0 -103000.0 -0.22 788134.0 73200.0 0.17 -0.0363 -0.1324 1168234 Maybridge3_000728 Clc1ccc(C(=O)N(CC#N)CC#N)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B03 compound treatment 558501.0 -242000.0 -0.51 834146.0 119000.0 0.27 -0.1716 -0.2955 2075539 Maybridge3_000729 CC(OC(=O)Nc1c(C)onc1c2ccccc2Cl)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B04 compound treatment 781545.0 -19300.0 -0.04 940421.0 225000.0 0.51 0.3336 0.6487 2075540 Maybridge3_000730 On1c(cc(cc1=O)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B05 compound treatment 805361.0 4550.0 0.01 922588.0 208000.0 0.47 0.3406 0.7214 2075541 Maybridge3_000731 CSC1=C(C#N)C(=O)NC(S1)c2ccccc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B06 compound treatment 917140.0 116000.0 0.25 914951.0 200000.0 0.45 0.4959 0.9587 2075542 Maybridge3_000732 CS(=O)(=O)NC(=N)c1ccncc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B07 compound treatment 792331.0 -8480.0 -0.02 861914.0 147000.0 0.33 0.2235 0.6681 2075543 Maybridge3_000733 FC(F)(F)c1cc(C#CCN2CCOCC2)cc(c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B08 compound treatment 800565.0 -249.0 0.0 871582.0 157000.0 0.36 0.2514 0.7061 1537560 Maybridge3_000734 CC1CN(CC(C)O1)c2ccc(N)cc2C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B09 compound treatment 808694.0 7880.0 0.02 878955.0 164000.0 0.37 0.2755 0.738 2075544 Maybridge3_000735 Oc1ccccc1C2NC(=NO2)CC(=O)N3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B10 compound treatment 1080155.0 279000.0 0.59 932148.0 217000.0 0.49 0.7679 0.9959 1599729 Maybridge3_000736 CC(=O)NCc1c(C)onc1c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B11 compound treatment 762039.0 -38800.0 -0.08 918432.0 203000.0 0.46 0.269 0.5725 2075545 Maybridge3_000737 Clc1ccc(SCc2ccc(o2)C(=O)Nc3cccnc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B12 compound treatment 912583.0 112000.0 0.24 945454.0 231000.0 0.52 0.5381 0.9356 2075546 Maybridge3_000738 COc1ccc(OC(=O)c2c(Cl)cccc2Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B13 compound treatment 843059.0 42200.0 0.09 931994.0 217000.0 0.49 0.4123 0.822 2075547 Maybridge3_000739 NC1=C(C#N)C(C(=C(O1)c2ccco2)C#N)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B14 compound treatment 856077.0 55300.0 0.12 911224.0 196000.0 0.45 0.3984 0.8635 1638414 Maybridge3_000740 CC1CN(CC(C)O1)C(=O)CCCC(=O)N2CC(C)OC(C)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B15 compound treatment 822528.0 21700.0 0.05 926208.0 211000.0 0.48 0.3722 0.7713 2075548 Maybridge3_000741 COc1ccc(OC(=O)c2snnc2C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B16 compound treatment 795329.0 -5490.0 -0.01 823761.0 109000.0 0.25 0.1667 0.6731 2075549 Maybridge3_000742 Nc1ccccc1SC(CC(=O)c2cccs2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B17 compound treatment 759538.0 -41300.0 -0.09 724415.0 9460.0 0.02 -0.0467 -0.5178 2075550 Maybridge3_000743 Cc1cccc(CS(=O)(=O)c2ccc(Cl)cc2)c1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B18 compound treatment 780482.0 -20300.0 -0.04 914325.0 199000.0 0.45 0.29 0.637 2075551 Maybridge3_000744 Oc1ccccc1/C=N/c2n[nH]c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B19 compound treatment 884331.0 83500.0 0.18 940120.0 225000.0 0.51 0.4872 0.8994 2075552 Maybridge3_000745 Clc1ccc(CNc2cccc(Cl)c2C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B20 compound treatment 866582.0 65800.0 0.14 860210.0 145000.0 0.33 0.3321 0.9265 2075553 Maybridge3_000746 Clc1cccc(Cl)c1CSC(=S)N2CCSCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B21 compound treatment 937613.0 137000.0 0.29 885124.0 170000.0 0.39 0.4786 0.9899 2075554 Maybridge3_000747 CN(C)c1ccc(/C=N/O)c(F)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B22 compound treatment 905791.0 105000.0 0.22 884983.0 170000.0 0.39 0.4307 0.9656 2075555 Maybridge3_000748 Cc1cc(cc(C)c1F)S(=O)(=O)NC(=N)c2ccccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B23 mock treatment 803455.0 2640.0 0.01 801511.0 86600.0 0.2 0.1431 0.7269 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 B24 mock treatment 456816.0 -344000.0 -0.73 458129.0 -257000.0 -0.58 -0.9285 -0.9939 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C01 compound treatment 610026.0 -191000.0 -0.4 549296.0 -166000.0 -0.38 -0.5523 -0.9994 1260995 Maybridge3_000749 O=C(c1ccccc1)c2ccc3ccccc3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C02 compound treatment 624796.0 -176000.0 -0.37 801213.0 86300.0 0.2 -0.1252 -0.297 2075556 Maybridge3_000750 Brc1ccc2NC(=O)/C(=C\C(=O)c3ccc4OCOc4c3)/c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C03 compound treatment 869253.0 68400.0 0.15 879986.0 165000.0 0.38 0.3679 0.9145 1154181 Maybridge3_000751 O=C(C1CCCCC1)N2CCN(CC2)c3ncccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C04 compound treatment 792561.0 -8250.0 -0.02 906447.0 191000.0 0.44 0.2955 0.6781 2075557 Maybridge3_000752 Brc1ccc(CS(=N)Nc2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C05 compound treatment 909888.0 109000.0 0.23 1064654.0 350000.0 0.8 0.7257 0.8764 1714598 Maybridge3_000753 COC(=O)c1ccccc1S(=O)(=O)NC2C(C)(C)C3CCC2(C)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C06 compound treatment 903706.0 103000.0 0.22 920507.0 206000.0 0.47 0.4847 0.9398 617 Maybridge3_000754 COc1cc(OC)c(/C=C\2/C(=O)Nc3ccccc23)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C07 compound treatment 940189.0 139000.0 0.3 951721.0 237000.0 0.54 0.5896 0.9601 1286190 Maybridge3_000755 COc1ccccc1N2CCN(Cc3cccc4ccccc34)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C08 compound treatment 939582.0 139000.0 0.29 961823.0 247000.0 0.56 0.6049 0.9546 2075558 Maybridge3_000756 NS(=O)(=O)/C=C/c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C09 compound treatment 994619.0 194000.0 0.41 896908.0 182000.0 0.41 0.583 1.0 1255945 Maybridge3_000757 COc1ccc(CSCC(=O)NC2CC3CCC(C2)N3C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C10 compound treatment 917887.0 117000.0 0.25 1003822.0 289000.0 0.66 0.6399 0.9114 1614043 Maybridge3_000758 Clc1c(NC(=O)c2ccccc2C(=O)NCc3cccnc3)sc4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C11 compound treatment 914250.0 113000.0 0.24 1001342.0 286000.0 0.65 0.6305 0.9083 1053995 Maybridge3_000759 N#Cc1ccccc1c2ccccc2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C12 compound treatment 866028.0 65200.0 0.14 1143631.0 429000.0 0.97 0.7869 0.7994 1252316 Maybridge3_000760 COc1cccc(C2Nc3ccccc3S2)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C13 compound treatment 947570.0 147000.0 0.31 1024260.0 309000.0 0.7 0.7172 0.9327 2075559 Maybridge3_000761 CSC(=S)OCC1(CC2CC3CC(C2)C1)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C14 compound treatment 853910.0 53100.0 0.11 1026386.0 311000.0 0.71 0.5803 0.8094 1195010 Maybridge3_000762 Cc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccccc3)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C15 compound treatment 954123.0 153000.0 0.33 1030346.0 315000.0 0.72 0.7369 0.936 1557640 Maybridge3_000763 OCC1CN(Cc2ccccc2)C(=O)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C16 compound treatment 867953.0 67100.0 0.14 899630.0 185000.0 0.42 0.3975 0.8967 2075560 Maybridge3_000764 Cc1c(C)c(C)c(CSc2nnc(CC#N)n2C)c(C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C17 compound treatment 868795.0 68000.0 0.14 882384.0 167000.0 0.38 0.3711 0.9117 2075561 Maybridge3_000765 CS(=O)(=O)c1ncc(OCc2ccccc2)cn1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C18 compound treatment 901580.0 101000.0 0.21 967834.0 253000.0 0.57 0.5576 0.9091 2075562 Maybridge3_000766 Clc1ccc(cc1)c2noc(CSc3ccccn3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C19 compound treatment 846932.0 46100.0 0.1 902189.0 187000.0 0.43 0.3701 0.8474 1011473 Maybridge3_000767 NC(=O)C1CCCCC1C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C20 compound treatment 902821.0 102000.0 0.22 962287.0 247000.0 0.56 0.5505 0.9138 1503216 Maybridge3_000768 COc1ccc(cc1)C(CC(=O)N)CC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C21 compound treatment 820383.0 19600.0 0.04 977439.0 262000.0 0.6 0.4513 0.7544 2075563 Maybridge3_000769 C/C(=N\O)/C(=O)Nc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C22 compound treatment 826328.0 25500.0 0.05 892343.0 177000.0 0.4 0.3234 0.7948 2075564 Maybridge3_000770 Clc1ccc(cc1)c2nc(CSc3ccccn3)cs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C23 mock treatment 797051.0 -3760.0 -0.01 793088.0 78100.0 0.18 0.12 0.6747 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 C24 mock treatment 616194.0 -185000.0 -0.39 456407.0 -259000.0 -0.59 -0.6924 -0.9805 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D01 compound treatment 376784.0 -424000.0 -0.9 502765.0 -212000.0 -0.48 -0.9768 -0.9574 2075565 Maybridge3_000771 Oc1ccccc1/C=N/c2nc(cs2)c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D02 compound treatment 646489.0 -154000.0 -0.33 932430.0 217000.0 0.49 0.1183 0.1995 2075566 Maybridge3_000772 CN(C)C(=S)SCc1ccc(cc1)C(=O)Oc2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D03 compound treatment 750645.0 -50200.0 -0.11 951680.0 237000.0 0.54 0.3054 0.5566 2075567 Maybridge3_000773 COC(=S)Nc1ccc(cc1)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D04 compound treatment 838589.0 37800.0 0.08 927837.0 213000.0 0.48 0.3989 0.813 2075568 Maybridge3_000774 Cc1nnsc1C(=O)NCCc2c[nH]c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D05 compound treatment 834897.0 34100.0 0.07 894309.0 179000.0 0.41 0.3394 0.8196 2075569 Maybridge3_000775 Cc1ncc(CSc2ccccn2)c(CO)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D06 compound treatment 996950.0 196000.0 0.42 1009744.0 295000.0 0.67 0.7679 0.9736 1137680 Maybridge3_000776 CCN(CCC#N)C(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D07 compound treatment 952419.0 152000.0 0.32 1056093.0 341000.0 0.78 0.7757 0.9239 1309582 Maybridge3_000777 Fc1cccc(F)c1C(=O)Nc2ccccc2C(=O)NCc3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D08 compound treatment 927876.0 127000.0 0.27 1090764.0 376000.0 0.85 0.7946 0.887 1686550 Maybridge3_000778 Cc1onc(c1C(=O)NCCO)c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D09 compound treatment 990584.0 190000.0 0.4 1137735.0 423000.0 0.96 0.9642 0.9253 2075570 Maybridge3_000779 COc1cc(Cl)c(cc1NC(=O)C)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D10 compound treatment 987163.0 186000.0 0.4 944571.0 230000.0 0.52 0.6485 0.9905 2075571 Maybridge3_000780 CCN(CC)C(=S)Oc1ccc(Br)cc1C(=O)NCCc2ccncc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D11 compound treatment 902000.0 101000.0 0.21 1266141.0 551000.0 1.25 1.0378 0.8163 2075572 Maybridge3_000781 Clc1ccc(SCc2ccc(o2)C(=O)N3CCOCC3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D12 compound treatment 967996.0 167000.0 0.35 1251978.0 537000.0 1.22 1.114 0.8762 2075573 Maybridge3_000782 Fc1cccc(NCCCn2ccnc2)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D13 compound treatment 1028055.0 227000.0 0.48 1229233.0 514000.0 1.17 1.1674 0.9232 2075574 Maybridge3_000783 CS/C(=C(/C#N)\C(=O)c1ccco1)/Nc2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D14 compound treatment 987913.0 187000.0 0.4 1288500.0 574000.0 1.3 1.2025 0.8823 1563197 Maybridge3_000784 O=C(CCCC(=O)N1CCCC1)N2CCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D15 compound treatment 979396.0 179000.0 0.38 1033231.0 318000.0 0.72 0.7794 0.9543 1593642 Maybridge3_000785 Cc1nnsc1C(=O)Oc2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D16 compound treatment 814378.0 13600.0 0.03 1214005.0 499000.0 1.13 0.8226 0.7248 2075575 Maybridge3_000786 CC(=O)NCCc1c(F)cccc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D17 compound treatment 957007.0 156000.0 0.33 1284336.0 569000.0 1.29 1.1495 0.8603 2075576 Maybridge3_000787 Cc1csc(n1)c2snnc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D18 compound treatment 916367.0 116000.0 0.24 1290570.0 576000.0 1.31 1.0986 0.8251 2075577 Maybridge3_000788 CCOC(=O)NCCc1c(F)cccc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D19 compound treatment 893012.0 92200.0 0.2 1171273.0 456000.0 1.04 0.8718 0.8258 2075578 Maybridge3_000789 OC1(CC1)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D20 compound treatment 922895.0 122000.0 0.26 1255050.0 540000.0 1.23 1.0513 0.8377 1315234 Maybridge3_000790 Clc1cc(CSC(=S)N2CCSCC2)c3OCOCc3c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D21 compound treatment 954404.0 154000.0 0.33 1226282.0 511000.0 1.16 1.0523 0.8716 2075579 Maybridge3_000791 CCc1nc(cs1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D22 compound treatment 926725.0 126000.0 0.27 1101118.0 386000.0 0.88 0.8096 0.8822 1677375 Maybridge3_000792 NS(=O)(=O)c1ccccc1Oc2ccc(Cl)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D23 mock treatment 935220.0 134000.0 0.28 1001335.0 286000.0 0.65 0.6619 0.9313 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 D24 mock treatment 765854.0 -35000.0 -0.07 476684.0 -238000.0 -0.54 -0.4355 -0.7964 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E01 compound treatment 850038.0 49200.0 0.1 756138.0 41200.0 0.09 0.14 0.9985 1451192 Maybridge3_000793 COC(=O)C1C2C=CCC2=C(C(=O)OC)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E02 compound treatment 570527.0 -230000.0 -0.49 583474.0 -131000.0 -0.3 -0.5566 -0.9723 2075580 Maybridge3_000794 O=C1/C(=C/c2cccc3ccccc23)/Nc4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E03 compound treatment 849623.0 48800.0 0.1 1040486.0 326000.0 0.74 0.5965 0.7982 2075581 Maybridge3_000795 FC(F)(F)c1cccc(c1)C(=O)N2CCN(CC2)c3cccc4[nH]ccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E04 compound treatment 916410.0 116000.0 0.25 972881.0 258000.0 0.59 0.5879 0.9251 2075582 Maybridge3_000796 N=C(Nc1ccccc1)SCc2ccc(C#N)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E05 compound treatment 903276.0 102000.0 0.22 1037218.0 322000.0 0.73 0.6717 0.8789 1607133 Maybridge3_000797 CC1(C)C(NC(=O)C2CCC2)C3(C)CCC1C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E06 compound treatment 941289.0 140000.0 0.3 1007187.0 292000.0 0.66 0.6804 0.9345 2075583 Maybridge3_000798 COc1ccc(/C=C\2/C(=O)Nc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E07 compound treatment 997853.0 197000.0 0.42 1030536.0 316000.0 0.72 0.8027 0.9669 1297748 Maybridge3_000799 Nc1ccc(cc1)C(=O)Oc2ccc(Oc3ccccc3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E08 compound treatment 939725.0 139000.0 0.29 1154232.0 439000.0 1.0 0.9144 0.8782 2075584 Maybridge3_000800 COc1cc(cc(OC)c1OC)C2SC(=C(C#N)C(=N2)O)SC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E09 compound treatment 942111.0 141000.0 0.3 1113502.0 399000.0 0.91 0.8525 0.8933 1614928 Maybridge3_000801 CN1C2CCC1CC(C2)NC(=O)CSc3nnc(N)s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E10 compound treatment 1051949.0 251000.0 0.53 1067142.0 352000.0 0.8 0.9427 0.9803 1586400 Maybridge3_000802 O=C(Nc1ccccc1C(=O)NCc2cccnc2)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E11 compound treatment 1157212.0 356000.0 0.76 1148015.0 433000.0 0.98 1.2305 0.9914 2075585 Maybridge3_000803 COC(=O)NC1(CCCC2CCC1)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E12 compound treatment 1146868.0 346000.0 0.73 1590176.0 875000.0 1.99 1.9258 0.9081 2075586 Maybridge3_000804 Cc1ccc(NC(=O)CSCc2ccc(C#N)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E13 compound treatment 1350202.0 549000.0 1.16 1332028.0 617000.0 1.4 1.8156 0.9957 1644876 Maybridge3_000805 CCC1(CC2CC3(C1)NC(=O)C)CC(C2)(C3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E14 compound treatment 1205365.0 405000.0 0.86 1203030.0 488000.0 1.11 1.3911 0.9919 1374505 Maybridge3_000806 OC(=O)c1ccccc1c2ccccc2C(=O)Nc3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E15 compound treatment 1091361.0 291000.0 0.62 1235033.0 520000.0 1.18 1.2716 0.9538 2075587 Maybridge3_000807 CC(C)(C)N1CC(CO)OC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E16 compound treatment 1042235.0 241000.0 0.51 1174395.0 459000.0 1.04 1.1005 0.9461 2075588 Maybridge3_000808 N/C(=N\O)/c1ccc2OCOc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E17 compound treatment 1153136.0 352000.0 0.75 1080592.0 366000.0 0.83 1.116 0.9986 1054635 Maybridge3_000809 CSc1ncc(OCc2ccccc2)c(O)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E18 compound treatment 1176761.0 376000.0 0.8 1164425.0 449000.0 1.02 1.2861 0.9924 2075589 Maybridge3_000810 CC(=O)OCc1c(C)c(C)c(C)c(C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E19 compound treatment 1162414.0 362000.0 0.77 1117372.0 402000.0 0.91 1.189 0.9961 2075590 Maybridge3_000811 CC1CC(C(CC1C)C(=O)O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E20 compound treatment 1019276.0 218000.0 0.46 1209153.0 494000.0 1.12 1.122 0.9232 1390420 Maybridge3_000812 Cc1cc(C)c(C(=O)N)c(CC(C)(C)C(=O)O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E21 compound treatment 1106274.0 305000.0 0.65 1200367.0 485000.0 1.1 1.2383 0.9677 2075591 Maybridge3_000813 COC(=O)C(=C(C)C)c1ccc(cc1)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E22 compound treatment 1162255.0 361000.0 0.77 1135999.0 421000.0 0.96 1.2187 0.9939 2075592 Maybridge3_000814 CSc1nc2ccccc2n3cccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E23 mock treatment 1117110.0 316000.0 0.67 956359.0 241000.0 0.55 0.8622 0.9951 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 E24 mock treatment 662100.0 -139000.0 -0.29 659434.0 -55500.0 -0.13 -0.2972 -0.9287 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F01 compound treatment 834403.0 33600.0 0.07 677139.0 -37800.0 -0.09 -0.0104 -0.0935 2075593 Maybridge3_000815 FC(F)(F)c1cccc(c1)/C(=C/c2cccnc2)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F02 compound treatment 1007837.0 207000.0 0.44 1004646.0 290000.0 0.66 0.7761 0.9805 2075594 Maybridge3_000816 Clc1ccc(C(=O)NCc2cccs2)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F03 compound treatment 1179391.0 379000.0 0.8 1036861.0 322000.0 0.73 1.085 0.9989 2075595 Maybridge3_000817 Fc1cccc(F)c1C(=O)NCCCn2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F04 compound treatment 1159216.0 358000.0 0.76 1122495.0 408000.0 0.93 1.1924 0.9951 2075596 Maybridge3_000818 Cc1onc(c1CC#N)c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F05 compound treatment 971921.0 171000.0 0.36 949790.0 235000.0 0.53 0.634 0.9823 1042708 Maybridge3_000819 Cc1ncc(CSc2ccc(Cl)cc2)c(CO)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F06 compound treatment 1126264.0 325000.0 0.69 1162906.0 448000.0 1.02 1.208 0.982 1132871 Maybridge3_000820 Oc1ccccc1C(=O)NCc2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F07 compound treatment 949009.0 148000.0 0.31 1160351.0 445000.0 1.01 0.9382 0.8849 2075597 Maybridge3_000821 Fc1cccc(F)c1CN2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F08 compound treatment 1061436.0 261000.0 0.55 1140588.0 426000.0 0.97 1.075 0.9647 2075598 Maybridge3_000822 Cc1snc(c1C(=O)O)c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F09 compound treatment 1108478.0 308000.0 0.65 1170459.0 456000.0 1.04 1.1935 0.9752 2075599 Maybridge3_000823 NC(=O)c1nnn(c1c2ccccc2)c3cccc(c3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F10 compound treatment 972858.0 172000.0 0.36 1222082.0 507000.0 1.15 1.0732 0.8874 1691543 Maybridge3_000824 Clc1cccc(Oc2ccc(cc2)S(=O)(=O)N3CCOCC3)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F11 compound treatment 1130795.0 330000.0 0.7 1379700.0 665000.0 1.51 1.5633 0.9387 1296871 Maybridge3_000825 CN(C)c1c(F)cc(cc1F)c2nnn[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F12 compound treatment 1098769.0 298000.0 0.63 1406790.0 692000.0 1.57 1.5589 0.9197 2075600 Maybridge3_000826 Fc1ccc(N/C=N/c2ccc(F)cc2F)c(F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F13 compound treatment 964445.0 164000.0 0.35 1396953.0 682000.0 1.55 1.3417 0.8444 1531556 Maybridge3_000827 COc1cccc(Oc2ccc(OC)cc2C(=O)O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F14 compound treatment 1064216.0 263000.0 0.56 1788082.0 1070000.0 2.44 2.1201 0.847 2075601 Maybridge3_000828 CC(C)(C)NC1=C(C#N)C(=O)NC(S1)c2ccccc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F15 compound treatment 864700.0 63900.0 0.14 1630172.0 915000.0 2.08 1.5671 0.7515 2075602 Maybridge3_000829 Clc1ccc(OC(=O)c2snnc2c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F16 compound treatment 988848.0 188000.0 0.4 1186847.0 472000.0 1.07 1.0405 0.9091 1384617 Maybridge3_000830 Clc1ccc(cc1Cl)S(=O)(=O)N2CCSCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F17 compound treatment 916774.0 116000.0 0.25 1150675.0 436000.0 0.99 0.8743 0.8566 2075603 Maybridge3_000831 CCOC(=O)Nc1c(C)noc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F18 compound treatment 1150497.0 350000.0 0.74 1198658.0 484000.0 1.1 1.3018 0.9816 2075604 Maybridge3_000832 CCOC(=O)Nc1nc2cc(C)ccc2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F19 compound treatment 925172.0 124000.0 0.26 1196293.0 481000.0 1.09 0.9602 0.853 1342849 Maybridge3_000833 Fc1cccc(Cl)c1CNCc2c(F)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F20 compound treatment 1161368.0 361000.0 0.76 1138929.0 424000.0 0.96 1.2221 0.9934 2075605 Maybridge3_000834 Oc1cc(CSC(=S)N2CCSCC2)c3ccccc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F21 compound treatment 1100383.0 300000.0 0.64 1271306.0 556000.0 1.26 1.3435 0.9492 2075606 Maybridge3_000835 C(c1cccs1)n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F22 compound treatment 1134620.0 334000.0 0.71 1144250.0 429000.0 0.98 1.1905 0.9875 1167965 Maybridge3_000836 Clc1ccc(Oc2ccccc2S(=O)(=O)N3CCOCC3)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F23 mock treatment 1190072.0 389000.0 0.83 840022.0 125000.0 0.28 0.7846 0.8989 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 F24 mock treatment 453983.0 -347000.0 -0.74 400819.0 -314000.0 -0.71 -1.0249 -0.9999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G01 compound treatment 844016.0 43200.0 0.09 843732.0 129000.0 0.29 0.2718 0.886 1004045 Maybridge3_000837 COC1=CC(=O)C(=CC1=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G02 compound treatment 964539.0 164000.0 0.35 770032.0 55100.0 0.13 0.334 0.9051 2075607 Maybridge3_000838 FC(F)(F)c1cccc(Nc2nnc(s2)c3cccnc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G03 compound treatment 901521.0 101000.0 0.21 886217.0 171000.0 0.39 0.4263 0.96 1649197 Maybridge3_000839 O=C(N1CCN(CC1)c2cccc3[nH]ccc23)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G04 compound treatment 1047636.0 247000.0 0.52 969809.0 255000.0 0.58 0.7797 0.9987 2075608 Maybridge3_000840 NC(=N)SCc1ccc(C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G05 compound treatment 1048090.0 247000.0 0.52 957722.0 243000.0 0.55 0.761 0.9997 1527173 Maybridge3_000841 CN1C2CCC1CC(C2)NS(=O)(=O)c3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G06 compound treatment 1112484.0 312000.0 0.66 955216.0 240000.0 0.55 0.8535 0.9955 2075609 Maybridge3_000842 O=C/1Nc2ccccc2\C1=C/c3cccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G07 compound treatment 1104051.0 303000.0 0.64 887768.0 173000.0 0.39 0.7324 0.9721 1433728 Maybridge3_000843 O=C(OC1CN2CCC1CC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G08 compound treatment 1075799.0 275000.0 0.58 1009941.0 295000.0 0.67 0.8864 0.9976 2075610 Maybridge3_000844 CSC1=C(C#N)C(=O)NC(S1)c2cccc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G09 compound treatment 1260369.0 460000.0 0.97 993121.0 278000.0 0.63 1.1361 0.9781 1032294 Maybridge3_000845 CN(C)N=Nc1ccc(C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G10 compound treatment 1378601.0 578000.0 1.22 1013173.0 298000.0 0.68 1.3456 0.9611 2075611 Maybridge3_000846 O=C(CSc1nnc(SCC(=O)c2ccccc2)s1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G11 compound treatment 1335540.0 535000.0 1.13 1342788.0 628000.0 1.43 1.8109 0.9935 2075612 Maybridge3_000847 C/C(=N/O)/C1(CCC2CC1)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G12 compound treatment 1497706.0 697000.0 1.48 1439516.0 725000.0 1.65 2.2095 0.9985 1578875 Maybridge3_000848 COc1ccc(NC(=O)CSCC(=O)N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G13 compound treatment 1385861.0 585000.0 1.24 1011854.0 297000.0 0.68 1.3543 0.9591 2075613 Maybridge3_000849 CC1(CC2(C)CC3(C)C1)CC(CO)(C2)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G14 compound treatment 1252850.0 452000.0 0.96 1079658.0 365000.0 0.83 1.2639 0.9974 2075614 Maybridge3_000850 COc1cc(OC)c(cc1Cl)N2C(=O)C=CC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G15 compound treatment 1288346.0 488000.0 1.03 1136493.0 422000.0 0.96 1.4085 0.9993 1709987 Maybridge3_000851 Cc1ccc(OCC2CN(Cc3ccccc3)C(=O)O2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G16 compound treatment 1145904.0 345000.0 0.73 948801.0 234000.0 0.53 0.8932 0.9877 1165784 Maybridge3_000852 CCOC(=O)C(Cc1c(C)c(C)c(C)c(C)c1C)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G17 compound treatment 1157420.0 357000.0 0.76 1025256.0 310000.0 0.71 1.0334 0.9994 1054634 Maybridge3_000853 Nc1ncc(OCc2ccccc2)c(O)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G18 compound treatment 1155438.0 355000.0 0.75 955270.0 240000.0 0.55 0.9179 0.9877 1392212 Maybridge3_000854 Clc1ccc(cc1)c2noc(CN3CCOCC3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G19 compound treatment 1202249.0 401000.0 0.85 960710.0 246000.0 0.56 0.9969 0.9792 2075615 Maybridge3_000855 O/N=C(\CN1CCCCC1)/c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G20 compound treatment 969711.0 169000.0 0.36 871155.0 156000.0 0.36 0.5043 1.0 2075616 Maybridge3_000856 FC(F)(F)c1cccc(CS(=O)(=O)c2ccc(Cl)cc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G21 compound treatment 1030099.0 229000.0 0.49 1006672.0 292000.0 0.66 0.8127 0.9883 2075617 Maybridge3_000857 C/C(=N\O)/C(=C)c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G22 compound treatment 1013838.0 213000.0 0.45 1005877.0 291000.0 0.66 0.787 0.9827 1617420 Maybridge3_000858 Cc1ccc-2c(NC(c3cccn32)c4ccc(cc4)C(=O)O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G23 mock treatment 1091795.0 291000.0 0.62 682174.0 -32800.0 -0.07 0.3835 0.6172 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 G24 mock treatment 721885.0 -78900.0 -0.17 553670.0 -161000.0 -0.37 -0.3776 -0.9368 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H01 compound treatment 789337.0 -11500.0 -0.02 798646.0 83700.0 0.19 0.1173 0.6117 2075618 Maybridge3_000859 CCOC(=O)C(C(Nc1ccc(F)cc1)c2ccccn2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H02 compound treatment 1057298.0 256000.0 0.54 1077552.0 363000.0 0.82 0.9674 0.9796 2075619 Maybridge3_000860 CN(C)C(=S)SCc1c(C)onc1c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H03 compound treatment 962885.0 162000.0 0.34 1193020.0 478000.0 1.09 1.0115 0.8874 2075620 Maybridge3_000861 COC(=S)Nc1cccc(c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H04 compound treatment 950976.0 150000.0 0.32 1295884.0 581000.0 1.32 1.159 0.8531 2075621 Maybridge3_000862 Nc1cccc(F)c1C(=O)NCc2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H05 compound treatment 1026975.0 226000.0 0.48 1252106.0 537000.0 1.22 1.2026 0.9166 1122553 Maybridge3_000863 Cc1ncc(CSc2ccccc2N)c(CO)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H06 compound treatment 1175784.0 375000.0 0.79 1445319.0 730000.0 1.66 1.7363 0.9431 2075622 Maybridge3_000864 CC(=O)NCc1c(Cl)cccc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H07 compound treatment 1403452.0 603000.0 1.28 1465576.0 751000.0 1.71 2.1101 0.9898 1406262 Maybridge3_000865 Fc1cccc(F)c1C(=O)Nc2ccc(nc2)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H08 compound treatment 1153089.0 352000.0 0.75 1305221.0 590000.0 1.34 1.477 0.9617 2075623 Maybridge3_000866 CC1(CO)CS/C(=N\c2ccc(F)cc2F)/N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H09 compound treatment 1550460.0 750000.0 1.59 1698832.0 984000.0 2.24 2.7055 0.986 1240423 Maybridge3_000867 Fc1cccc(F)c1C(=O)Oc2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H10 compound treatment 1457637.0 657000.0 1.39 1045514.0 331000.0 0.75 1.516 0.9581 1428324 Maybridge3_000868 Clc1cc(Cl)cc(NC(=O)CCN2CCOCC2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H11 compound treatment 1410903.0 610000.0 1.29 1595783.0 881000.0 2.0 2.3306 0.9776 2075624 Maybridge3_000869 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NC(=N)c2ccncc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H12 compound treatment 1574086.0 773000.0 1.64 1454486.0 740000.0 1.68 2.3481 0.9999 2075625 Maybridge3_000870 Cc1nn(C)c(C)c1Cc2c(F)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H13 compound treatment 1252869.0 452000.0 0.96 1616252.0 901000.0 2.05 2.1266 0.9401 1163257 Maybridge3_000871 Cc1onc(c1C(=O)N(CC=C)CC=C)c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H14 compound treatment 1655127.0 854000.0 1.81 1714413.0 999000.0 2.27 2.8874 0.9937 2075626 Maybridge3_000872 O=C(/C=C/1\NC(=O)CS1)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H15 compound treatment 1416774.0 616000.0 1.31 1372614.0 658000.0 1.5 1.9806 0.9977 2075627 Maybridge3_000873 Cc1nnsc1C(=O)Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H16 compound treatment 1263439.0 463000.0 0.98 760362.0 45400.0 0.1 0.7665 0.7772 2075628 Maybridge3_000874 Cc1c(C)c(C)c(CN2CCSCC2)c(C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H17 compound treatment 1439963.0 639000.0 1.35 1345423.0 630000.0 1.43 1.9717 0.9996 1289132 Maybridge3_000875 Fc1cccc(NCc2cccnc2)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H18 compound treatment 1493326.0 693000.0 1.47 1461699.0 747000.0 1.7 2.2386 0.9974 2075629 Maybridge3_000876 N#Cc1cnc(nc1c2cccs2)c3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H19 compound treatment 1135251.0 334000.0 0.71 1133034.0 418000.0 0.95 1.1735 0.9896 2075630 Maybridge3_000877 CSc1nnc(s1)n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H20 compound treatment 1061951.0 261000.0 0.55 935905.0 221000.0 0.5 0.7467 0.9988 2075631 Maybridge3_000878 Cc1cc(cc(C)c1F)S(=O)(=O)Nc2ccc(F)c(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H21 compound treatment 1060256.0 259000.0 0.55 967580.0 253000.0 0.57 0.795 0.9998 2075632 Maybridge3_000879 CN(C)S(=O)(=O)Nc1cccc(c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H22 compound treatment 958711.0 158000.0 0.33 982927.0 268000.0 0.61 0.6675 0.9602 1470715 Maybridge3_000880 Cc1ncc(CSc2nc(cs2)C(C)(C)C)c(CO)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H23 mock treatment 989916.0 189000.0 0.4 853139.0 138000.0 0.31 0.5056 0.9927 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 H24 mock treatment 873136.0 72300.0 0.15 862480.0 148000.0 0.34 0.3456 0.9371 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I01 compound treatment 1005003.0 204000.0 0.43 903170.0 188000.0 0.43 0.6087 1.0 1627512 Maybridge3_000881 OC(C(O)C(=O)N1CCCC1)C(=O)N2CCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I02 compound treatment 1086017.0 285000.0 0.6 1076383.0 361000.0 0.82 1.0086 0.9886 1244598 Maybridge3_000882 NC(=O)c1cc(nc2ccc(Br)cc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I03 compound treatment 1006741.0 206000.0 0.44 963439.0 248000.0 0.56 0.7082 0.9919 1200031 Maybridge3_000883 O=C(N1CCN(CC1)c2cccc3[nH]ccc23)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I04 compound treatment 998968.0 198000.0 0.42 1014781.0 300000.0 0.68 0.7791 0.973 2075633 Maybridge3_000884 N#CCSc1nsc(SCC#N)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I05 compound treatment 1220925.0 420000.0 0.89 1160886.0 446000.0 1.01 1.3467 0.9979 1240063 Maybridge3_000885 CN1C2CCC1CC(C2)NS(=O)(=O)c3ccc(NC(=O)C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I06 compound treatment 1066975.0 266000.0 0.56 1150482.0 436000.0 0.99 1.0992 0.9644 2075634 Maybridge3_000886 Clc1ccc(/C=C\2/C(=O)Nc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I07 compound treatment 1102261.0 301000.0 0.64 1233686.0 519000.0 1.18 1.2858 0.9586 1259827 Maybridge3_000887 COC(=O)c1c(O)c2ccccc2[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I08 compound treatment 1007960.0 207000.0 0.44 1073740.0 359000.0 0.82 0.8873 0.9578 2075635 Maybridge3_000888 CSC1=C(C#N)C(=O)NC(S1)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I09 compound treatment 1114862.0 314000.0 0.67 1156795.0 442000.0 1.0 1.1811 0.98 2075636 Maybridge3_000889 CC1(C)C2CCC1(C)c3n[nH]c(c23)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I10 compound treatment 1261143.0 460000.0 0.98 1236615.0 522000.0 1.19 1.5287 0.9953 1405984 Maybridge3_000890 Clc1ccc(cc1Cl)C(=O)Nc2ccccc2C(=O)NCCc3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I11 compound treatment 1153203.0 352000.0 0.75 1491781.0 777000.0 1.77 1.7771 0.9267 2075637 Maybridge3_000891 C/C(=N/O)/C1(CCCC2CCC1)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I12 compound treatment 1590022.0 789000.0 1.67 1270840.0 556000.0 1.26 2.0767 0.9904 1604606 Maybridge3_000892 CCC(O)(c1ccccc1)c2ccccc2N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I13 compound treatment 1425495.0 625000.0 1.32 1519920.0 805000.0 1.83 2.2305 0.9874 1343794 Maybridge3_000893 CCOC(=O)CSCN1CCCCC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I14 compound treatment 1644899.0 844000.0 1.79 1482957.0 768000.0 1.75 2.5 0.9999 1420540 Maybridge3_000894 Cc1c(C)c(C)c(C(=O)CCCC(=O)O)c(C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I15 compound treatment 1319251.0 518000.0 1.1 1423620.0 709000.0 1.61 1.9164 0.9826 2075638 Maybridge3_000895 CN(C)C(=O)COc1ccc2ccccc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I16 compound treatment 1127955.0 327000.0 0.69 1306144.0 591000.0 1.34 1.4408 0.9526 2075639 Maybridge3_000896 O=C/1Nc2ccccc2\C1=C/C3CC4CC3C=C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I17 compound treatment 1397129.0 596000.0 1.26 1218625.0 504000.0 1.15 1.7036 0.9988 2075640 Maybridge3_000897 Cn1c2CCC(Cn3ccnc3)C(=O)c2c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I18 compound treatment 1198044.0 397000.0 0.84 1342829.0 628000.0 1.43 1.6049 0.9683 1457705 Maybridge3_000898 Clc1ccc(cc1)c2noc(CN3CCCC3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I19 compound treatment 1159909.0 359000.0 0.76 1157882.0 443000.0 1.01 1.2504 0.9905 1264910 Maybridge3_000899 COC(=O)c1ccc(NC(=O)C)c(c1)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I20 compound treatment 1351869.0 551000.0 1.17 1046027.0 331000.0 0.75 1.3583 0.9774 2075641 Maybridge3_000900 FC(F)(F)c1cccc(CSC2=NCCCN2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I21 compound treatment 1353351.0 553000.0 1.17 1223774.0 509000.0 1.16 1.6463 1.0 1342131 Maybridge3_000901 CCOC(=O)C1(CCC(=NO)CC1)C(=O)OCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I22 compound treatment 1160660.0 360000.0 0.76 1157850.0 443000.0 1.01 1.2514 0.9906 2075642 Maybridge3_000902 Cc1ccnc(NC(=O)CSc2ccccn2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I23 mock treatment 1352792.0 552000.0 1.17 1078322.0 363000.0 0.83 1.4116 0.9855 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 I24 mock treatment 885994.0 85200.0 0.18 615154.0 -99800.0 -0.23 -0.0328 -0.1129 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J01 compound treatment 489582.0 -311000.0 -0.66 479422.0 -236000.0 -0.54 -0.8452 -0.9946 1694044 Maybridge3_000903 CCNc1cc(=N)n(CC)c2sc(C(=O)OCC)c(N)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J02 compound treatment 903413.0 103000.0 0.22 1009338.0 294000.0 0.67 0.6271 0.891 2075643 Maybridge3_000904 CN(C)C(=S)SCc1nc(no1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J03 compound treatment 825363.0 24500.0 0.05 982325.0 267000.0 0.61 0.4666 0.7648 2075644 Maybridge3_000905 COC(=S)Nc1ccc(Cl)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J04 compound treatment 1028006.0 227000.0 0.48 1058090.0 343000.0 0.78 0.8922 0.9731 2075645 Maybridge3_000906 Cc1c(C)c(sc1C(=O)N)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J05 compound treatment 1174870.0 374000.0 0.79 1216983.0 502000.0 1.14 1.3678 0.9842 2075646 Maybridge3_000907 Cc1ncc(CSc2ccccc2/N=C/c3cc(Cl)cc(Cl)c3O)c(CO)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J06 compound treatment 1421655.0 621000.0 1.32 1343199.0 628000.0 1.43 1.9407 0.9992 2075647 Maybridge3_000908 CC(=N)NS(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J07 compound treatment 1186525.0 386000.0 0.82 1205207.0 490000.0 1.11 1.3663 0.9884 2075648 Maybridge3_000909 CSc1nc2c(C)c(C)c(C)c(C)c2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J08 compound treatment 1059861.0 259000.0 0.55 1234751.0 520000.0 1.18 1.224 0.9392 1259138 Maybridge3_000910 CN(C)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J09 compound treatment 1427009.0 626000.0 1.33 1329116.0 614000.0 1.4 1.926 0.9997 2075649 Maybridge3_000911 N/C(=N\O)/C=C/c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J10 compound treatment 1324373.0 524000.0 1.11 1471494.0 757000.0 1.72 2.0011 0.9775 1484889 Maybridge3_000912 OC(COc1ccc(Cl)cc1Cl)Cn2ccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J11 compound treatment 494089.0 -307000.0 -0.65 639251.0 -75700.0 -0.17 -0.5815 -0.8645 2075650 Maybridge3_000913 C=C(CN1CCN(CC(=C)C#N)CC1)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J12 compound treatment 1191083.0 390000.0 0.83 1612215.0 897000.0 2.04 2.0275 0.921 2075651 Maybridge3_000914 CSC1=C(C#N)C(=O)NC(S1)c2ccc(Cl)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J13 compound treatment 1587695.0 787000.0 1.67 1630845.0 916000.0 2.08 2.652 0.994 2075652 Maybridge3_000915 CSc1ccc(Cl)cc1NC(=O)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J14 compound treatment 1422750.0 622000.0 1.32 1748049.0 1030000.0 2.35 2.5932 0.9627 2075653 Maybridge3_000916 O=C(/C=C/1\NC(=O)CS1)N2CCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J15 compound treatment 1515276.0 714000.0 1.51 1483222.0 768000.0 1.75 2.3061 0.9975 1172931 Maybridge3_000917 COc1ccc(cc1OC)S(=O)(=O)NCc2c(F)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J16 compound treatment 1371887.0 571000.0 1.21 1377836.0 663000.0 1.51 1.9217 0.9941 2075654 Maybridge3_000918 Clc1cccc(N2CCSCC2)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J17 compound treatment 1029193.0 228000.0 0.48 1244943.0 530000.0 1.2 1.1944 0.9198 2075655 Maybridge3_000919 COC(=O)c1cccc(CS(=O)(=O)C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J18 compound treatment 1189774.0 389000.0 0.82 1329829.0 615000.0 1.4 1.5716 0.9683 2075656 Maybridge3_000920 Cc1c(nnn1c2ccc(F)cc2F)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J19 compound treatment 1143901.0 343000.0 0.73 1162360.0 447000.0 1.02 1.2336 0.9865 2075657 Maybridge3_000921 OC(=O)c1cc(NC(=O)/C=C/c2cccs2)ccc1N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J20 compound treatment 1121347.0 321000.0 0.68 1111477.0 397000.0 0.9 1.118 0.9903 1413162 Maybridge3_000922 Clc1cccc(Cl)c1C(C#N)N2CCSCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J21 compound treatment 1182887.0 382000.0 0.81 1179633.0 465000.0 1.06 1.3198 0.9914 2075658 Maybridge3_000923 CS(=O)(=O)Cc1cc(Cl)cc2COCOc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J22 compound treatment 1103367.0 303000.0 0.64 957846.0 243000.0 0.55 0.844 0.9972 1613619 Maybridge3_000924 Cc1c(nnn1c2ccccc2Oc3ccc(Cl)cc3Cl)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J23 mock treatment 908018.0 107000.0 0.23 914802.0 200000.0 0.45 0.482 0.9487 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 J24 mock treatment 765183.0 -35600.0 -0.08 582190.0 -133000.0 -0.3 -0.2668 -0.8576 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K01 compound treatment 836095.0 35300.0 0.07 693988.0 -21000.0 -0.05 0.0192 0.2163 2075659 Maybridge3_000925 Cn1c(nc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K02 compound treatment 822474.0 21700.0 0.05 991483.0 277000.0 0.63 0.477 0.7567 2075660 Maybridge3_000926 Cc1c(C)c(C)c(CC#N)c(C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K03 compound treatment 906574.0 106000.0 0.22 1022450.0 307000.0 0.7 0.6529 0.8893 1360936 Maybridge3_000927 Clc1cccc(Cl)c1C(=O)N2CCN(CC2)c3cccc4[nH]ccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K04 compound treatment 1013129.0 212000.0 0.45 1107391.0 392000.0 0.89 0.9492 0.9498 2075661 Maybridge3_000928 Cc1ncc(s1)c2ccc3ccccc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K05 compound treatment 988228.0 187000.0 0.4 1066918.0 352000.0 0.8 0.8468 0.9478 1458921 Maybridge3_000929 COc1ccccc1N2CCN(Cc3ccc(Cl)cc3Cl)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K06 compound treatment 1100305.0 299000.0 0.63 1271444.0 556000.0 1.27 1.3436 0.9491 2075662 Maybridge3_000930 O=C/1Nc2ccccc2\C1=C/c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K07 compound treatment 1094553.0 294000.0 0.62 1240096.0 525000.0 1.19 1.2846 0.954 1675252 Maybridge3_000931 CCC(C)c1ccc(NC(=O)CSc2ccccn2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K08 compound treatment 985476.0 185000.0 0.39 1198472.0 484000.0 1.1 1.0541 0.9033 1645450 Maybridge3_000932 NC(=O)c1c(N)c(sc1SCc2ccccc2)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K09 compound treatment 1006257.0 205000.0 0.44 1126800.0 412000.0 0.94 0.9701 0.9394 1015371 Maybridge3_000933 COc1c(CO)cc(C)cc1CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K10 compound treatment 1042448.0 242000.0 0.51 1136049.0 421000.0 0.96 1.0392 0.9571 2075663 Maybridge3_000934 N1C(c2cccn2-c3ccccc13)c4ccccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K11 compound treatment 1136443.0 336000.0 0.71 1212803.0 498000.0 1.13 1.3035 0.975 1922165 Maybridge3_000935 CC1(CC(=O)O1)C2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K12 compound treatment 1060428.0 260000.0 0.55 1544171.0 829000.0 1.89 1.7223 0.8769 2075664 Maybridge3_000936 Nc1ccccc1C(O)(Cc2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K13 compound treatment 1012263.0 211000.0 0.45 1478951.0 764000.0 1.74 1.5452 0.8614 2075665 Maybridge3_000937 FC(F)(F)c1cc([nH]n1)c2ccc(cc2)n3cccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K14 compound treatment 1301214.0 500000.0 1.06 1546246.0 831000.0 1.89 2.0865 0.9627 1667855 Maybridge3_000938 Cc1c(C)c(C)c(C(=O)c2ccccc2C(=O)N3CCOCC3)c(C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K15 compound treatment 1332789.0 532000.0 1.13 1671730.0 957000.0 2.18 2.3356 0.9532 1010990 Maybridge3_000939 OC(C(=O)OCc1ccccc1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K16 compound treatment 1141876.0 341000.0 0.72 1142946.0 428000.0 0.97 1.1993 0.9893 2075666 Maybridge3_000940 COc1ccc(cc1CN2CCCC2)/C(=N/O)/C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K17 compound treatment 1011753.0 211000.0 0.45 1271300.0 556000.0 1.26 1.2106 0.9024 2075667 Maybridge3_000941 C/C(=N\O)/c1nnn(c1C)c2cc(ccc2Cl)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K18 compound treatment 1098986.0 298000.0 0.63 1099230.0 384000.0 0.87 1.0648 0.9874 1618782 Maybridge3_000942 CCOC(=O)C1CCN(Cc2nc(no2)c3ccc(Cl)cc3)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K19 compound treatment 1122336.0 322000.0 0.68 1129396.0 414000.0 0.94 1.1482 0.9874 1474567 Maybridge3_000943 O=C(NC1CC2CCC1CC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K20 compound treatment 949843.0 149000.0 0.32 1188845.0 474000.0 1.08 0.9852 0.8775 1733607 Maybridge3_000944 Cc1cc(C)c(C(=O)Nc2ccccc2)c(CC(C)(C)C(=O)O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K21 compound treatment 954867.0 154000.0 0.33 1126711.0 412000.0 0.94 0.8929 0.9006 1193355 Maybridge3_000945 COc1ccc(cc1)C2(CC3CC4CC(O)(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K22 compound treatment 940154.0 139000.0 0.3 978607.0 264000.0 0.6 0.6327 0.9468 1565286 Maybridge3_000946 Oc1nc(CN2CCOCC2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K23 mock treatment 835430.0 34600.0 0.07 782042.0 67100.0 0.15 0.1597 0.9438 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 K24 mock treatment 676718.0 -124000.0 -0.26 441120.0 -274000.0 -0.62 -0.6262 -0.9266 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L01 compound treatment 687211.0 -114000.0 -0.24 761478.0 46500.0 0.11 -0.0955 -0.3631 1035084 Maybridge3_000947 NS(=O)(=O)c1cccc(c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L02 compound treatment 751365.0 -49400.0 -0.1 1115506.0 401000.0 0.91 0.5698 0.6216 2075668 Maybridge3_000948 CCc1cccc(C(C)C)c1NC(=O)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L03 compound treatment 1114477.0 314000.0 0.66 1188466.0 474000.0 1.08 1.2314 0.9732 2075669 Maybridge3_000949 COC(=S)Nc1ccc(F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L04 compound treatment 1024380.0 224000.0 0.47 1103541.0 389000.0 0.88 0.9598 0.9574 1575534 Maybridge3_000950 Nc1cc(nn1CCC#N)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L05 compound treatment 1099341.0 299000.0 0.63 1174987.0 460000.0 1.05 1.1871 0.971 2075670 Maybridge3_000951 N#CCc1nnc([nH]1)c2ccccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L06 compound treatment 1133297.0 332000.0 0.7 1394492.0 680000.0 1.54 1.5909 0.9368 1316531 Maybridge3_000952 Oc1ccc(Br)cc1C(=O)NCCc2ccncc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L07 compound treatment 974008.0 173000.0 0.37 1225474.0 511000.0 1.16 1.0804 0.8874 2075671 Maybridge3_000953 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2noc(CN3CCOCC3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L08 compound treatment 989787.0 189000.0 0.4 1258477.0 544000.0 1.24 1.1571 0.8907 2075672 Maybridge3_000954 OCC1(CO)CS/C(=N\c2ccc(F)c(Cl)c2)/N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L09 compound treatment 1038549.0 238000.0 0.5 1261246.0 546000.0 1.24 1.2346 0.9211 2075673 Maybridge3_000955 Clc1ccc(Cl)c(NC(=O)CC2SC(=NC2=O)NC3CC4CC3C=C4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L10 compound treatment 967757.0 167000.0 0.35 1282623.0 568000.0 1.29 1.1629 0.8689 2075674 Maybridge3_000956 Cc1cc(nn1c2ccccc2)C(=O)n3nc(C)c(Br)c3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L11 compound treatment 1111082.0 310000.0 0.66 1487394.0 772000.0 1.76 1.7069 0.9102 2075675 Maybridge3_000957 NC1=C(C#N)C(C(=C(O1)c2cccs2)C#N)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L12 compound treatment 731236.0 -69600.0 -0.15 1554462.0 840000.0 1.91 1.2453 0.6505 2075676 Maybridge3_000958 Clc1ccccc1NC2=C(C#N)C(=O)NC(S2)c3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L13 compound treatment 1049012.0 248000.0 0.53 1318795.0 604000.0 1.37 1.3428 0.9133 2075677 Maybridge3_000959 Fc1cccc(Cl)c1CN2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L14 compound treatment 1031668.0 231000.0 0.49 1633020.0 918000.0 2.09 1.822 0.8499 2075678 Maybridge3_000960 Cc1nn(c(C)c1C#N)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L15 compound treatment 973158.0 172000.0 0.37 1350051.0 635000.0 1.44 1.2794 0.859 2075679 Maybridge3_000961 NC(=O)c1snnc1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L16 compound treatment 1054168.0 253000.0 0.54 1331206.0 616000.0 1.4 1.3705 0.9134 2075680 Maybridge3_000962 CSc1ccc(Oc2cc(F)ccc2C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L17 compound treatment 1104298.0 303000.0 0.64 1447068.0 732000.0 1.66 1.6319 0.9145 2075681 Maybridge3_000963 COC(=O)c1ccccc1CS(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L18 compound treatment 1224067.0 423000.0 0.9 1357272.0 642000.0 1.46 1.6671 0.9726 2075682 Maybridge3_000964 Fc1ccccc1C(=O)Oc2cc(Cl)cc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L19 compound treatment 1028200.0 227000.0 0.48 1300404.0 585000.0 1.33 1.2821 0.9056 2075683 Maybridge3_000965 Fc1cccc(Cl)c1CSc2nnc(s2)n3cccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L20 compound treatment 1100460.0 300000.0 0.64 1095781.0 381000.0 0.87 1.0614 0.9884 2075684 Maybridge3_000966 N#CCSc1nsc(SCC#N)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L21 compound treatment 1181910.0 381000.0 0.81 1151583.0 437000.0 0.99 1.2732 0.9948 1042868 Maybridge3_000967 O=C(C1CCCCC1)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L22 compound treatment 1139481.0 339000.0 0.72 1137471.0 423000.0 0.96 1.1869 0.9897 2075685 Maybridge3_000968 Cc1c(nnn1c2cccc(Cl)c2C#N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L23 mock treatment 1190639.0 390000.0 0.83 1062684.0 348000.0 0.79 1.1434 0.9998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 L24 mock treatment 595483.0 -205000.0 -0.44 608993.0 -106000.0 -0.24 -0.4781 -0.9611 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M01 compound treatment 791116.0 -9700.0 -0.02 747129.0 32200.0 0.07 0.0372 0.4894 1247573 Maybridge3_000969 OC1(CCC2C1CCC2(O)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M02 compound treatment 1125756.0 325000.0 0.69 1049355.0 334000.0 0.76 1.0247 0.9988 2075686 Maybridge3_000970 O=C(CC1S/C(=N/c2ccccc2)/NC1=O)NCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M03 compound treatment 935344.0 135000.0 0.29 1067658.0 353000.0 0.8 0.7687 0.9032 1300102 Maybridge3_000971 Clc1ccc(cc1)C(=O)N2CCN(CC2)c3cccc4[nH]ccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M04 compound treatment 964238.0 163000.0 0.35 1152693.0 438000.0 1.0 0.9487 0.9003 2075687 Maybridge3_000972 CC(C)c1ccc(/N=C/c2ccc(NC(=O)C)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M05 compound treatment 1011685.0 211000.0 0.45 1195999.0 481000.0 1.09 1.0895 0.9221 1560877 Maybridge3_000973 COc1ccccc1N2CCN(Cc3ccccc3F)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M06 compound treatment 1169097.0 368000.0 0.78 1315579.0 601000.0 1.37 1.5177 0.9648 2075688 Maybridge3_000974 O=C/1Nc2ccccc2\C1=C/c3c[nH]c4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M07 compound treatment 1062985.0 262000.0 0.56 1250615.0 536000.0 1.22 1.2542 0.9369 1054918 Maybridge3_000975 COc1ccc(cc1Br)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M08 compound treatment 999666.0 199000.0 0.42 1205522.0 491000.0 1.12 1.0867 0.9114 2075689 Maybridge3_000976 COc1cc(ccc1O)C2NC(=O)C(=C(Nc3cccc(C)c3)S2)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M09 compound treatment 1176688.0 376000.0 0.8 1324992.0 610000.0 1.39 1.5442 0.9654 2075690 Maybridge3_000977 CC1(C)C2CCC1(C)c3nc(N)nc(c23)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M10 compound treatment 1039933.0 239000.0 0.51 1248199.0 533000.0 1.21 1.2157 0.9252 1622986 Maybridge3_000978 Nc1nc(nc2sc3CCCCCc3c12)c4ccncc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M11 compound treatment 1071639.0 271000.0 0.57 1352131.0 637000.0 1.45 1.4303 0.9179 2075691 Maybridge3_000979 COC(=O)C1(CCC(=O)C2(CCC1=O)C(=O)OC)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M12 compound treatment 1136743.0 336000.0 0.71 1399949.0 685000.0 1.56 1.6048 0.9371 2075692 Maybridge3_000980 O/N=C(\c1ccccc1)/c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M13 compound treatment 1123523.0 323000.0 0.68 1501969.0 787000.0 1.79 1.749 0.913 2075693 Maybridge3_000981 C/S(=N\S(=O)(=O)c1ccccc1)/c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M14 compound treatment 1004591.0 204000.0 0.43 1301670.0 587000.0 1.33 1.2487 0.8906 2075694 Maybridge3_000982 COc1cc(CSC2=NCCN2)cc(OC)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M15 compound treatment 1044811.0 244000.0 0.52 1350450.0 635000.0 1.44 1.3874 0.9041 1051739 Maybridge3_000983 OC(=O)CNC(=O)Cc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M16 compound treatment 1112444.0 312000.0 0.66 1302154.0 587000.0 1.34 1.4112 0.9474 2075695 Maybridge3_000984 NC(=N)SCc1nc(no1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M17 compound treatment 980329.0 180000.0 0.38 1232944.0 518000.0 1.18 1.1018 0.8903 1074888 Maybridge3_000985 O=C1CCCC(=O)C1CCC#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M18 compound treatment 971001.0 170000.0 0.36 1242371.0 527000.0 1.2 1.103 0.8809 1426775 Maybridge3_000986 CC1CCN(Cc2nc(no2)c3ccc(Cl)cc3)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M19 compound treatment 919151.0 118000.0 0.25 1293523.0 579000.0 1.32 1.1075 0.8271 2075696 Maybridge3_000987 NC(=O)C1CC2CCC1CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M20 compound treatment 1131453.0 331000.0 0.7 1315403.0 600000.0 1.37 1.4609 0.952 2075697 Maybridge3_000988 Nc1ccccc1SCc2nc(no2)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M21 compound treatment 1153526.0 353000.0 0.75 1294670.0 580000.0 1.32 1.4607 0.9639 1537706 Maybridge3_000989 COC(=O)C1(CC2CC3C1)CC(C2)(C3)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M22 compound treatment 1164171.0 363000.0 0.77 1064055.0 349000.0 0.79 1.1059 0.9999 2075698 Maybridge3_000990 O=c1[nH]c(CN2CCCCC2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M23 mock treatment 1161656.0 361000.0 0.76 1067557.0 353000.0 0.8 1.1078 0.9997 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 M24 mock treatment 607598.0 -193000.0 -0.41 694789.0 -20200.0 -0.05 -0.3221 -0.7814 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N01 compound treatment 871131.0 70300.0 0.15 845795.0 131000.0 0.3 0.3158 0.949 2075699 Maybridge3_000991 FC(F)(F)c1cccc(c1)S(=O)(=O)n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N02 compound treatment 1145690.0 345000.0 0.73 1133694.0 419000.0 0.95 1.1902 0.9915 2075700 Maybridge3_000992 CCOC(=S)SCc1nc(no1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N03 compound treatment 1159429.0 359000.0 0.76 1156104.0 441000.0 1.0 1.2468 0.9907 1121997 Maybridge3_000993 COc1cccc(Oc2ccccc2C(=O)O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N04 compound treatment 1148261.0 347000.0 0.74 1145951.0 431000.0 0.98 1.2137 0.9901 2075701 Maybridge3_000994 Cc1ccc(cc1)c2nc(O)cc(n2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N05 compound treatment 1028800.0 228000.0 0.48 1154869.0 440000.0 1.0 1.049 0.9443 2075702 Maybridge3_000995 FC(F)(F)c1cc(cc(c1)S(=O)(=O)Nc2cccnc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N06 compound treatment 1005320.0 205000.0 0.43 1223797.0 509000.0 1.16 1.1246 0.9103 2075703 Maybridge3_000996 Clc1cccc(c1C#N)n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N07 compound treatment 1076064.0 275000.0 0.58 1337730.0 623000.0 1.42 1.4138 0.9232 2075704 Maybridge3_000997 OC(=O)c1nnn(c1c2ccccc2)c3cccc(c3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N08 compound treatment 1007891.0 207000.0 0.44 1230156.0 515000.0 1.17 1.1387 0.9103 2075705 Maybridge3_000998 CN(NS(=O)(=O)c1ccc(Cl)c(Cl)c1)c2cccc(F)c2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N09 compound treatment 1082940.0 282000.0 0.6 1420645.0 706000.0 1.6 1.5574 0.9096 2075706 Maybridge3_000999 OC(=O)c1ccc(CSc2ccc(Cl)cc2)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N10 compound treatment 883526.0 82700.0 0.18 1260810.0 546000.0 1.24 1.0015 0.7991 2075707 Maybridge3_001000 Cn1nccc1c2cc(Cl)cc(Cl)c2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N11 compound treatment 1184329.0 384000.0 0.81 1135110.0 420000.0 0.96 1.2504 0.9968 1102307 Maybridge3_001001 N#CC(CN1CCOCC1)CN2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N12 compound treatment 1203568.0 403000.0 0.85 1224860.0 510000.0 1.16 1.4235 0.9887 1633599 Maybridge3_001002 Fc1ccc(NC(=O)CCCC(=O)Nc2ccc(F)cc2F)c(F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N13 compound treatment 1005240.0 204000.0 0.43 1269826.0 555000.0 1.26 1.1985 0.8985 1719890 Maybridge3_001003 Fc1cccc(Cl)c1CN2CCN(Cc3c(F)cccc3Cl)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N14 compound treatment 1054805.0 254000.0 0.54 1417872.0 703000.0 1.6 1.5108 0.8959 2075708 Maybridge3_001004 O/N=C/c1cc(Cl)cs1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N15 compound treatment 1199190.0 398000.0 0.84 1353423.0 638000.0 1.45 1.6236 0.9668 2075709 Maybridge3_001005 N/C(=N\O)/c1snnc1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N16 compound treatment 1028071.0 227000.0 0.48 1382999.0 668000.0 1.52 1.4146 0.8878 2075710 Maybridge3_001006 Clc1ccc(C(=O)N2CCSCC2)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N17 compound treatment 1092124.0 291000.0 0.62 1160487.0 446000.0 1.01 1.1529 0.9718 1150414 Maybridge3_001007 OCCNc1cccc(F)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N18 compound treatment 959705.0 159000.0 0.34 1213671.0 499000.0 1.13 1.0399 0.8792 2075711 Maybridge3_001008 CSCC(=N)NS(=O)(=O)c1ccc(Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N19 compound treatment 1227468.0 427000.0 0.9 1293389.0 578000.0 1.32 1.5695 0.9833 2075712 Maybridge3_001009 CCOC(=O)C(C#N)C(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N20 compound treatment 1188422.0 388000.0 0.82 1356687.0 642000.0 1.46 1.6127 0.9631 1641517 Maybridge3_001010 Fc1cccc(NCCc2ccc(Cl)cc2)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N21 compound treatment 1178148.0 377000.0 0.8 1302084.0 587000.0 1.33 1.5095 0.97 2075713 Maybridge3_001011 CS/C(=N\c1ccccc1F)/Nc2ccccc2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N22 compound treatment 1163648.0 363000.0 0.77 1124574.0 410000.0 0.93 1.2024 0.9955 2075714 Maybridge3_001012 CCOC(=S)SCc1cc(F)cc2COCOc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N23 mock treatment 1094725.0 294000.0 0.62 1065820.0 351000.0 0.8 1.0047 0.9925 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 N24 mock treatment 649717.0 -151000.0 -0.32 605770.0 -109000.0 -0.25 -0.402 -0.9921 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O01 compound treatment 570984.0 -230000.0 -0.49 610127.0 -105000.0 -0.24 -0.513 -0.9459 2075715 Maybridge3_001013 N1C(Oc2ccccc12)C3Nc4ccccc4O3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O02 compound treatment 1073290.0 272000.0 0.58 1104520.0 390000.0 0.89 1.0347 0.9786 2073392 Maybridge3_001014 NC(=N)SCc1ccc(F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O03 compound treatment 1039370.0 239000.0 0.51 1261074.0 546000.0 1.24 1.2356 0.9216 1532488 Maybridge3_001015 O=S(=O)(N1CCN(CC1)c2cccc3[nH]ccc23)c4ccc(C#N)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O04 compound treatment 953688.0 153000.0 0.32 1283919.0 569000.0 1.29 1.1439 0.8578 2075716 Maybridge3_001016 Oc1ccc(Cl)cc1/C=N/c2ccc3cn[nH]c3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O05 compound treatment 1103410.0 303000.0 0.64 1296135.0 581000.0 1.32 1.3879 0.9449 1307355 Maybridge3_001017 COc1ccccc1N2CCN(Cc3ccc(C)cc3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O06 compound treatment 1053526.0 253000.0 0.54 1380352.0 665000.0 1.51 1.4485 0.9026 2075717 Maybridge3_001018 CCOc1cc(OCC)c(/C=N/O)c(OCC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O07 compound treatment 1043478.0 243000.0 0.51 1094027.0 379000.0 0.86 0.9732 0.9696 2075718 Maybridge3_001019 COc1cc(SC)c(OC)cc1SC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O08 compound treatment 1106336.0 306000.0 0.65 1315399.0 600000.0 1.37 1.4233 0.942 2075719 Maybridge3_001020 Cc1cccc(NC2=C(C#N)C(=O)NC3(CCCC3)S2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O09 compound treatment 1079385.0 279000.0 0.59 1338668.0 624000.0 1.42 1.4203 0.9246 1399951 Maybridge3_001021 CC(=O)OCc1ccccc1S(=O)(=O)c2ccccc2COC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O10 compound treatment 1104827.0 304000.0 0.64 1367327.0 652000.0 1.48 1.5045 0.9303 2075720 Maybridge3_001022 COc1ccc(CC/C(=C\2/C(=O)Nc3ccccc23)/C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O11 compound treatment 1032196.0 231000.0 0.49 1275480.0 561000.0 1.27 1.248 0.9139 2075721 Maybridge3_001023 CC1(CCCC2(CCC1)C(=O)O)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O12 compound treatment 1020963.0 220000.0 0.47 1354677.0 640000.0 1.45 1.3585 0.8893 2075722 Maybridge3_001024 NC(=N)SCc1cccc(C#N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O13 compound treatment 1063276.0 262000.0 0.56 1205891.0 491000.0 1.12 1.1827 0.9483 1428708 Maybridge3_001025 OC(=O)Cc1ccccc1Sc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O14 compound treatment 997109.0 196000.0 0.42 1323430.0 608000.0 1.38 1.2725 0.8808 2075723 Maybridge3_001026 COc1ccc(cc1CSc2ccccn2)/C(=N/O)/C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O15 compound treatment 1006075.0 205000.0 0.44 1240045.0 525000.0 1.19 1.1519 0.9065 1018022 Maybridge3_001027 OCC1C(CO)C2c3ccccc3C1c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O16 compound treatment 942062.0 141000.0 0.3 1196740.0 482000.0 1.1 0.9863 0.8685 2075724 Maybridge3_001028 Clc1ccc(cc1)c2noc(CSC3=NCCN3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O17 compound treatment 921416.0 121000.0 0.26 1406516.0 692000.0 1.57 1.2926 0.8114 2075725 Maybridge3_001029 CCC(C)(C)/C(=N/O)/c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O18 compound treatment 981839.0 181000.0 0.38 1278267.0 563000.0 1.28 1.177 0.8803 1056307 Maybridge3_001030 Clc1ccccc1C2C(C#N)(C#N)C2(C#N)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O19 compound treatment 949899.0 149000.0 0.32 1151818.0 437000.0 0.99 0.9258 0.8882 2075726 Maybridge3_001031 CC(C)(O)C1(CCC2(C)CC1)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O20 compound treatment 927174.0 126000.0 0.27 1393261.0 678000.0 1.54 1.2799 0.8177 2075727 Maybridge3_001032 FC(F)(F)c1cc(NC(=O)CC#N)cc(c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O21 compound treatment 1085418.0 285000.0 0.6 1221250.0 506000.0 1.15 1.2406 0.9546 1451360 Maybridge3_001033 OC(C1CCNCC1)(c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O22 compound treatment 1041453.0 241000.0 0.51 1135513.0 421000.0 0.96 1.0368 0.9567 1682023 Maybridge3_001034 Nc1ccccc1SCc2nc3ccccc3c(=O)[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O23 mock treatment 936092.0 135000.0 0.29 965488.0 251000.0 0.57 0.6056 0.9496 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 O24 mock treatment 507321.0 -293000.0 -0.62 584889.0 -130000.0 -0.3 -0.6491 -0.9422 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P01 compound treatment 454839.0 -346000.0 -0.73 485790.0 -229000.0 -0.52 -0.887 -0.986 2075728 Maybridge3_001035 Cc1onc(c1C(=O)n2cccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P02 compound treatment 517407.0 -283000.0 -0.6 544832.0 -170000.0 -0.39 -0.6983 -0.9773 2075729 Maybridge3_001036 NC(=O)CC(=O)c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P03 compound treatment 706067.0 -94700.0 -0.2 784108.0 69200.0 0.16 -0.0309 -0.121 1362369 Maybridge3_001037 CSC1=C(C#N)C(=O)NC2(CCCCC2)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P04 compound treatment 760243.0 -40600.0 -0.09 851788.0 137000.0 0.31 0.1592 0.4931 1317178 Maybridge3_001038 O=c1cc(oc(=O)[nH]1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P05 compound treatment 781007.0 -19800.0 -0.04 985988.0 271000.0 0.62 0.406 0.6574 2075730 Maybridge3_001039 NC(=O)CCNc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P06 compound treatment 830818.0 30000.0 0.06 966730.0 252000.0 0.57 0.4497 0.7809 2075731 Maybridge3_001040 CSc1cccc(NC(=O)c2ccccc2F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P07 compound treatment 823903.0 23100.0 0.05 911176.0 196000.0 0.45 0.3501 0.78 2075732 Maybridge3_001041 CC1CCN(Cc2nc(no2)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P08 compound treatment 686940.0 -114000.0 -0.24 757539.0 42600.0 0.1 -0.1022 -0.3931 2075733 Maybridge3_001042 OCC1(CO)CS/C(=N\c2cc(Cl)cc(Cl)c2)/N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P09 compound treatment 864526.0 63700.0 0.14 786510.0 71600.0 0.16 0.2105 0.9957 1723199 Maybridge3_001043 CN(C)c1c(F)cc(cc1F)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P10 compound treatment 784643.0 -16200.0 -0.03 804337.0 89400.0 0.2 0.1195 0.5796 2075734 Maybridge3_001044 CC(C)(C)Sc1ccccc1/C=N/O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P11 compound treatment 779844.0 -21000.0 -0.04 737837.0 22900.0 0.05 0.0054 0.0783 1707999 Maybridge3_001045 Nc1n[nH]c(Nc2cccc(Cl)c2Cl)c1C(=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P12 compound treatment 666512.0 -134000.0 -0.28 729213.0 14300.0 0.03 -0.1784 -0.6226 2075735 Maybridge3_001046 O=C(CCCC(=O)Nc1cccnc1)Nc2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P13 compound treatment 674061.0 -127000.0 -0.27 780833.0 65900.0 0.15 -0.0841 -0.2734 2075736 Maybridge3_001047 O/N=C(/C(=O)c1ccco1)\c2nc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P14 compound treatment 676834.0 -124000.0 -0.26 815843.0 101000.0 0.23 -0.0237 -0.0678 2075737 Maybridge3_001048 Fc1ccc(NC(=O)/C=C/C(=O)Nc2ccc(F)c(Cl)c2)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P15 compound treatment 747366.0 -53400.0 -0.11 917383.0 202000.0 0.46 0.2453 0.5176 2075738 Maybridge3_001049 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NCCCN2CCOCC2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P16 compound treatment 803016.0 2200.0 0.0 1022582.0 308000.0 0.7 0.4979 0.7118 2075739 Maybridge3_001050 Fc1cccc(F)c1C(=O)N2CCSCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P17 compound treatment 711937.0 -88900.0 -0.19 549708.0 -165000.0 -0.38 -0.3989 -0.9491 2075740 Maybridge3_001051 Clc1c(Br)ccc(N2CCCC2)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P18 compound treatment 618013.0 -183000.0 -0.39 981165.0 266000.0 0.61 0.1539 0.2142 2075741 Maybridge3_001052 CN(NC(=N)C)c1cccc(F)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P19 compound treatment 1122031.0 321000.0 0.68 1219796.0 505000.0 1.15 1.2931 0.9689 2075742 Maybridge3_001053 Clc1cccc(NCc2cccs2)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P20 compound treatment 1116649.0 316000.0 0.67 1157089.0 442000.0 1.01 1.1842 0.9805 2075743 Maybridge3_001054 Cc1cc(cc(C)c1F)S(=O)(=O)NC(=N)c2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P21 compound treatment 704380.0 -96400.0 -0.2 896448.0 181000.0 0.41 0.1472 0.3197 2075744 Maybridge3_001055 O=C(N(CC#N)CC#N)c1cccs1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P22 compound treatment 523110.0 -278000.0 -0.59 836155.0 121000.0 0.28 -0.2214 -0.3407 1643711 Maybridge3_001056 Nc1nnc(SCc2cc(F)cc3COCOc23)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P23 mock treatment 472349.0 -328000.0 -0.7 669704.0 -45200.0 -0.1 -0.5651 -0.8029 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1433 P24 mock treatment 453149.0 -348000.0 -0.74 510425.0 -205000.0 -0.47 -0.85 -0.9753 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A01 compound treatment 425783.0 -453000.0 -0.96 484522.0 -448000.0 -1.02 -1.3985 -0.9996 2075745 Maybridge3_001057 Cn1c(SCc2cc(F)cc3COCOc23)nnc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A02 compound treatment 668488.0 -210000.0 -0.44 776898.0 -155000.0 -0.35 -0.5646 -0.9935 2075746 Maybridge3_001058 CC1=C(OC(=O)c2cccs2)C(=O)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A03 compound treatment 623502.0 -255000.0 -0.54 719253.0 -213000.0 -0.48 -0.7247 -0.9985 1367326 Maybridge3_001059 Cc1onc(c1C(O)c2ccc(F)cc2)c3c(F)cccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A04 compound treatment 808562.0 -69800.0 -0.15 853002.0 -79400.0 -0.18 -0.2323 -0.9951 2075747 Maybridge3_001060 CC1SCC(CS1)NS(=O)(=O)c2cc(Cl)sc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A05 compound treatment 828304.0 -50100.0 -0.11 827162.0 -105000.0 -0.24 -0.2442 -0.9331 1220212 Maybridge3_001061 Cc1nn(CCC#N)c(C)c1Cc2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A06 compound treatment 780959.0 -97400.0 -0.21 776826.0 -156000.0 -0.35 -0.3961 -0.9672 2075748 Maybridge3_001062 OC(=O)c1cccc(C(=O)O)c1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A07 compound treatment 578502.0 -300000.0 -0.64 681442.0 -251000.0 -0.57 -0.8529 -0.9985 1708285 Maybridge3_001063 Fc1c(CSC(=S)N2CCOCC2)cccc1CSC(=S)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A08 compound treatment 869650.0 -8730.0 -0.02 795161.0 -137000.0 -0.31 -0.2337 -0.7477 1248512 Maybridge3_001064 Cc1noc(C)c1S(=O)(=O)Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A09 compound treatment 874258.0 -4120.0 -0.01 827208.0 -105000.0 -0.24 -0.1753 -0.7324 2075749 Maybridge3_001065 Brc1ccc2oc(cc2c1)c3cc[nH]n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A10 compound treatment 704639.0 -174000.0 -0.37 837554.0 -94800.0 -0.22 -0.4129 -0.9675 2075750 Maybridge3_001066 CS/C(=N\C#N)/NCc1c(N)cccc1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A11 compound treatment 790576.0 -87800.0 -0.19 811959.0 -120000.0 -0.27 -0.3252 -0.9823 2075751 Maybridge3_001067 CSC(=NS(=O)(=O)c1cc(Cl)sc1Cl)SC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A12 compound treatment 883315.0 4940.0 0.01 606248.0 -326000.0 -0.74 -0.5169 -0.6971 1418653 Maybridge3_001068 Nc1ccc(Oc2c(C#N)cccc2C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A13 compound treatment 791544.0 -86800.0 -0.18 799015.0 -133000.0 -0.3 -0.3446 -0.9714 2075752 Maybridge3_001069 O=S(=O)(CS(=O)(=O)NCc1cccs1)NCc2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A14 compound treatment 819904.0 -58500.0 -0.12 421268.0 -511000.0 -1.16 -0.9093 -0.7781 2075753 Maybridge3_001070 CC(C)(C)C(=O)C(C#N)C(=O)Nc1ccc(Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A15 compound treatment 879132.0 757.0 0.0 995549.0 63200.0 0.14 0.1027 0.715 2075754 Maybridge3_001071 CC(C)NC(=O)n1ccc(n1)c2sc(C)nc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A16 compound treatment 855168.0 -23200.0 -0.05 990555.0 58200.0 0.13 0.0587 0.4162 1739347 Maybridge3_001072 Clc1ccc(cc1)S(=O)(=O)Nc2n[nH]c3cccc(Cl)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A17 compound treatment 674061.0 -204000.0 -0.43 965014.0 32600.0 0.07 -0.2538 -0.5776 2075755 Maybridge3_001073 COc1ccc(cc1)c2c[nH]nc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A18 compound treatment 762944.0 -115000.0 -0.24 1030154.0 97800.0 0.22 -0.0159 -0.048 1497137 Maybridge3_001074 Cc1cc(NC(=O)CSCC(=O)O)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A19 compound treatment 937071.0 58700.0 0.12 1099673.0 167000.0 0.38 0.3569 0.8919 2075756 Maybridge3_001075 CN(C1CC2CC1C=C2)C(=O)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A20 compound treatment 978206.0 99800.0 0.21 1159142.0 227000.0 0.52 0.5142 0.9227 2075757 Maybridge3_001076 Oc1nccn(c2c(F)cccc2F)c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A21 compound treatment 792355.0 -86000.0 -0.18 842866.0 -89500.0 -0.2 -0.2729 -0.9985 2075758 Maybridge3_001077 CS/C(=N\S(=O)(=O)c1ccccc1)/Nc2c(C)nn(C)c2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A22 compound treatment 571433.0 -307000.0 -0.65 818629.0 -114000.0 -0.26 -0.643 -0.9183 1497628 Maybridge3_001078 CC(C)(C)c1ccc(cc1)c2cc(=O)[nH]c(=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A23 mock treatment 476102.0 -402000.0 -0.85 786769.0 -146000.0 -0.33 -0.8371 -0.9151 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 A24 mock treatment 488337.0 -390000.0 -0.83 485841.0 -447000.0 -1.02 -1.3026 -0.9948 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B01 compound treatment 405754.0 -473000.0 -1.0 826152.0 -106000.0 -0.24 -0.8793 -0.8531 1552202 Maybridge3_001079 Cc1nccnc1c2ccnn2S(=O)(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B02 compound treatment 842831.0 -35500.0 -0.08 920343.0 -12000.0 -0.03 -0.0726 -0.906 1394454 Maybridge3_001080 CC1C(OCCN1C(=O)c2c(C)onc2c3ccccc3Cl)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B03 compound treatment 958949.0 80600.0 0.17 1038598.0 106000.0 0.24 0.2915 0.9856 1168145 Maybridge3_001081 Clc1ccc(cc1)c2cncn2N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B04 compound treatment 998122.0 120000.0 0.25 993814.0 61400.0 0.14 0.2783 0.9604 2075759 Maybridge3_001082 OC(=O)c1ccc(/N=C/c2cccs2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B05 compound treatment 982506.0 104000.0 0.22 878260.0 -54100.0 -0.12 0.0691 0.2734 1227005 Maybridge3_001083 CCn1cc(C(=O)O)c(=O)c2cc(Cl)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B06 compound treatment 1079141.0 201000.0 0.43 1130459.0 198000.0 0.45 0.6194 0.9996 1679835 Maybridge3_001084 N#CCc1ccc(NC2(C#N)C3CC4CC(C3)CC2C4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B07 compound treatment 972974.0 94600.0 0.2 933700.0 1320.0 0.0 0.1439 0.7176 1173406 Maybridge3_001085 CCNc1sc(C(=O)OC)c(N)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B08 compound treatment 990026.0 112000.0 0.24 915883.0 -16500.0 -0.04 0.1408 0.5877 1222507 Maybridge3_001086 COc1cc(cc(OC)c1OC)C(=O)N(CCC#N)C2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B09 compound treatment 1065354.0 187000.0 0.4 939834.0 7450.0 0.02 0.2923 0.7367 1481233 Maybridge3_001087 Cc1nnc(NC(=O)c2ccccc2NC(=O)c3ccccc3)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B10 compound treatment 1141210.0 263000.0 0.56 875945.0 -56400.0 -0.13 0.3033 0.5304 2075760 Maybridge3_001088 Cn1nc(cc1OC(=O)c2ccccc2Cl)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B11 compound treatment 1096441.0 218000.0 0.46 892162.0 -40200.0 -0.09 0.2622 0.5565 2075761 Maybridge3_001089 COc1ccc(/C=C/2\CN(C)C/C(=C\c3ccc(OC)cc3)/C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B12 compound treatment 1287582.0 409000.0 0.87 1058074.0 126000.0 0.29 0.8155 0.8928 2075762 Maybridge3_001090 COc1cc(nc(N)n1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B13 compound treatment 1158120.0 280000.0 0.59 801858.0 -131000.0 -0.3 0.2095 0.3159 2075763 Maybridge3_001091 CC1CNC(=N1)SCc2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B14 compound treatment 1130283.0 252000.0 0.53 1023301.0 90900.0 0.21 0.5238 0.9147 1118789 Maybridge3_001092 COc1nc-2c(Cc3ccccc32)c(c4ccc[nH]4)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B15 compound treatment 1017652.0 139000.0 0.3 973312.0 40900.0 0.09 0.2746 0.887 2075764 Maybridge3_001093 CCc1nc(no1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B16 compound treatment 977527.0 99200.0 0.21 972662.0 40300.0 0.09 0.2134 0.9307 2075765 Maybridge3_001094 COC(=O)C1=C(N)Oc2ccccc2C1C(C#N)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B17 compound treatment 959859.0 81500.0 0.17 944353.0 12000.0 0.03 0.1414 0.8085 2075766 Maybridge3_001095 CCOC(=O)/C(=C(\C)/c1ccc(NC(=O)C)cc1)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B18 compound treatment 764224.0 -114000.0 -0.24 987739.0 55400.0 0.13 -0.0821 -0.3011 1619856 Maybridge3_001096 Cc1sc(N)c(C(=O)c2cccs2)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B19 compound treatment 1105763.0 227000.0 0.48 1157243.0 225000.0 0.51 0.7024 0.9996 2075767 Maybridge3_001097 Cc1ccc(cc1)c2cn3nc(sc3n2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B20 compound treatment 1070034.0 192000.0 0.41 1093580.0 161000.0 0.37 0.5465 0.9987 2075768 Maybridge3_001098 COC(=O)c1sccc1NC(=O)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B21 compound treatment 1062130.0 184000.0 0.39 1046702.0 114000.0 0.26 0.4592 0.9807 2075769 Maybridge3_001099 CC1CNC(=N1)c2ccccc2N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B22 compound treatment 960922.0 82500.0 0.17 983054.0 50700.0 0.12 0.2052 0.9794 1345582 Maybridge3_001100 CC1CN(CC(C)O1)c2ncnc3ccsc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B23 mock treatment 863088.0 -15300.0 -0.03 1006778.0 74400.0 0.17 0.0967 0.5614 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 B24 mock treatment 522353.0 -356000.0 -0.75 676290.0 -256000.0 -0.58 -0.9454 -0.9918 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C01 compound treatment 579773.0 -299000.0 -0.63 760811.0 -172000.0 -0.39 -0.7234 -0.9729 2075770 Maybridge3_001101 CCOC(=S)SCc1cc(Br)cc(Br)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C02 compound treatment 628777.0 -250000.0 -0.53 802127.0 -130000.0 -0.3 -0.5836 -0.9624 2075771 Maybridge3_001102 CC1=C(Sc2ccccc2)C(=NCCN1)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C03 compound treatment 716718.0 -162000.0 -0.34 834314.0 -98100.0 -0.22 -0.4 -0.9783 1441511 Maybridge3_001103 Cc1onc(c1C(=O)c2ccccc2O)c3c(F)cccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C04 compound treatment 798800.0 -79600.0 -0.17 971295.0 38900.0 0.09 -0.0567 -0.2978 2075772 Maybridge3_001104 Cc1cc(C)n(n1)C2=NCCN2S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C05 compound treatment 733409.0 -145000.0 -0.31 1054685.0 122000.0 0.28 -0.0207 -0.0499 2075773 Maybridge3_001105 Cc1cc(cc(C)c1F)S(=O)(=O)NC(=N)c2ccc(cc2)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C06 compound treatment 874145.0 -4230.0 -0.01 1041225.0 109000.0 0.25 0.1686 0.681 1630915 Maybridge3_001106 Clc1cccc(NC2CCSC2)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C07 compound treatment 1161114.0 283000.0 0.6 997475.0 65100.0 0.15 0.5285 0.856 2075774 Maybridge3_001107 OC(=C(C#N)C#N)c1c(Cl)cccc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C08 compound treatment 1068063.0 190000.0 0.4 1031148.0 98800.0 0.22 0.4431 0.9621 2075775 Maybridge3_001108 CSc1cc(n[nH]1)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C09 compound treatment 1081718.0 203000.0 0.43 1081410.0 149000.0 0.34 0.5444 0.9929 2075776 Maybridge3_001109 O=C(Nc1ccccc1)C(C#N)C(=O)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C10 compound treatment 827475.0 -50900.0 -0.11 950900.0 18500.0 0.04 -0.0465 -0.4017 1406131 Maybridge3_001110 NC(=O)C1CCN(CC1)S(=O)(=O)c2cc(Cl)sc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C11 compound treatment 934042.0 55700.0 0.12 1144787.0 212000.0 0.48 0.4249 0.8548 2075777 Maybridge3_001111 Clc1cc(c(Cl)s1)S(=O)(=O)n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C12 compound treatment 1152570.0 274000.0 0.58 1146745.0 214000.0 0.49 0.7556 0.9962 2075778 Maybridge3_001112 CC(C)(C)C(=O)NCCC1CC1(Cl)Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C13 compound treatment 1183727.0 305000.0 0.65 764803.0 -168000.0 -0.38 0.1883 0.2507 1121384 Maybridge3_001113 Cn1ncc(c1N)c2nc(cs2)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C14 compound treatment 1019879.0 142000.0 0.3 1055930.0 124000.0 0.28 0.4107 0.9995 2075779 Maybridge3_001114 COc1ccc(OCC(F)(F)F)c(c1)C(=O)Nc2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C15 compound treatment 939321.0 60900.0 0.13 1103354.0 171000.0 0.39 0.3662 0.894 2075780 Maybridge3_001115 CCc1c[nH]nc1c2c(F)cccc2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C16 compound treatment 1135016.0 257000.0 0.54 1098728.0 166000.0 0.38 0.6521 0.9842 1117781 Maybridge3_001116 Clc1cccc(Oc2ccc(cc2)c3ccn[nH]3)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C17 compound treatment 1034998.0 157000.0 0.33 1131675.0 199000.0 0.45 0.5552 0.9883 2075781 Maybridge3_001117 Clc1ccc(NC(=O)CC2=NC(=O)CS2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C18 compound treatment 1073551.0 195000.0 0.41 1182627.0 250000.0 0.57 0.6949 0.9878 1547445 Maybridge3_001118 Clc1cc(CN2CCSCC2)c(Cl)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C19 compound treatment 996126.0 118000.0 0.25 1042634.0 110000.0 0.25 0.3538 1.0 2075782 Maybridge3_001119 C(=C/c1cc[nH]n1)\C=C\c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C20 compound treatment 1091294.0 213000.0 0.45 1134933.0 203000.0 0.46 0.6448 0.9999 1278984 Maybridge3_001120 COc1ccc(Oc2cccc(Cl)c2CNC(=O)c3ccccc3N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C21 compound treatment 1186691.0 308000.0 0.65 1042106.0 110000.0 0.25 0.6386 0.9128 2075783 Maybridge3_001121 Oc1ccccc1C(=C)n2ccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C22 compound treatment 1021822.0 143000.0 0.3 1069651.0 137000.0 0.31 0.4357 0.9999 1103933 Maybridge3_001122 COC(=O)c1cc(O)n(C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C23 mock treatment 1021542.0 143000.0 0.3 1115281.0 183000.0 0.42 0.5086 0.988 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 C24 mock treatment 905693.0 27300.0 0.06 895191.0 -37200.0 -0.08 -0.0188 -0.1838 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D01 compound treatment 884297.0 5920.0 0.01 701724.0 -231000.0 -0.52 -0.3619 -0.69 1671574 Maybridge3_001123 C1CN(CCO1)c2cc(n[nH]2)c3ccc(Oc4ccccc4)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D02 compound treatment 512678.0 -366000.0 -0.78 785098.0 -147000.0 -0.33 -0.785 -0.9295 2075784 Maybridge3_001124 CC(NC(=O)C(C)(C)C)c1ccc(C)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D03 compound treatment 708754.0 -170000.0 -0.36 836321.0 -96100.0 -0.22 -0.4087 -0.9714 1248603 Maybridge3_001125 O=C(Nc1ccc(cc1)c2cnco2)C3CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D04 compound treatment 808335.0 -70000.0 -0.15 939089.0 6710.0 0.02 -0.0942 -0.6312 2075785 Maybridge3_001126 CN(CCC#N)c1ccc(/C=N/c2ccc(cc2)C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D05 compound treatment 787105.0 -91300.0 -0.19 956359.0 24000.0 0.05 -0.0983 -0.4889 1586772 Maybridge3_001127 CC1N(CCc2sccc12)C(=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D06 compound treatment 985715.0 107000.0 0.23 941935.0 9550.0 0.02 0.1763 0.7711 1310916 Maybridge3_001128 CC1CC(C)(C)CC1(Nc2ccc(CC#N)cc2)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D07 compound treatment 942383.0 64000.0 0.14 951343.0 19000.0 0.04 0.1264 0.888 2075786 Maybridge3_001129 Cc1ccc(cc1)C(=O)CN2C(=O)CCC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D08 compound treatment 907180.0 28800.0 0.06 962753.0 30400.0 0.07 0.092 0.9981 2075787 Maybridge3_001130 Fc1ccc(NC(=O)c2sc3ccccc3c2Cl)cc1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D09 compound treatment 892966.0 14600.0 0.03 956394.0 24000.0 0.05 0.0605 0.9638 2075788 Maybridge3_001131 Clc1ccc(cc1)c2nn3c(nnc3s2)c4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D10 compound treatment 1045826.0 167000.0 0.35 1044049.0 112000.0 0.25 0.4305 0.9865 2075789 Maybridge3_001132 Cn1nc(cc1OC(=O)c2cccs2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D11 compound treatment 992292.0 114000.0 0.24 1035402.0 103000.0 0.23 0.3364 0.9999 1024629 Maybridge3_001133 CC(C)(C)c1nc2ccccc2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D12 compound treatment 1323189.0 445000.0 0.94 964061.0 31700.0 0.07 0.7177 0.7589 2075790 Maybridge3_001134 O=C(C=C1SCCS1)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D13 compound treatment 1089711.0 211000.0 0.45 909279.0 -23100.0 -0.05 0.2797 0.62 2075791 Maybridge3_001135 CC1CN=C(N1)SCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D14 compound treatment 1173138.0 295000.0 0.62 1021866.0 89500.0 0.2 0.5857 0.8913 2075792 Maybridge3_001136 NC(=O)/C(=C/1\CCc2ccccc12)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D15 compound treatment 1059503.0 181000.0 0.38 1023909.0 91500.0 0.21 0.4187 0.9586 1373168 Maybridge3_001137 OC(=O)CCCc1nc(no1)c2ccccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D16 compound treatment 1181200.0 303000.0 0.64 1118336.0 186000.0 0.42 0.7529 0.9795 2075793 Maybridge3_001138 CCOC(=O)C1=C(N)Oc2ccccc2C1C(C#N)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D17 compound treatment 910870.0 32500.0 0.07 1081419.0 149000.0 0.34 0.2883 0.8338 1662876 Maybridge3_001139 OC(=O)CC1SC(=NC1=O)Cc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D18 compound treatment 914692.0 36300.0 0.08 1149968.0 218000.0 0.49 0.4042 0.8074 1167009 Maybridge3_001140 CCOC(=O)c1cc(CC)sc1NC(=O)CC#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D19 compound treatment 981505.0 103000.0 0.22 1194280.0 262000.0 0.6 0.5756 0.9075 1135722 Maybridge3_001141 Nc1ccc(Cl)cc1C(=O)NCc2ccccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D20 compound treatment 941377.0 63000.0 0.13 996838.0 64500.0 0.15 0.1981 0.9989 2075794 Maybridge3_001142 CCc1cc2c(OC(=O)N(C)C)ncnc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D21 compound treatment 1082900.0 205000.0 0.43 943633.0 11300.0 0.03 0.3247 0.7475 1231291 Maybridge3_001143 Nc1ccc(c(Cl)c1)S(=O)(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D22 compound treatment 916184.0 37800.0 0.08 938137.0 5750.0 0.01 0.0659 0.8118 1248952 Maybridge3_001144 Clc1cccc(Cl)c1CSc2nc3ccnn3c(=O)[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D23 mock treatment 1026779.0 148000.0 0.31 1050416.0 118000.0 0.27 0.4122 0.9969 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 D24 mock treatment 1159818.0 281000.0 0.6 1006789.0 74400.0 0.17 0.5415 0.8732 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E01 compound treatment 859755.0 -18600.0 -0.04 825059.0 -107000.0 -0.24 -0.2004 -0.811 2075795 Maybridge3_001145 Cc1cc(C)n(n1)C2=NCCN2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E02 compound treatment 1094347.0 216000.0 0.46 922561.0 -9820.0 -0.02 0.308 0.6718 2075796 Maybridge3_001146 CC1=C(OC(=O)/C=C/c2ccccc2)C(=O)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E03 compound treatment 1072553.0 194000.0 0.41 885297.0 -47100.0 -0.11 0.2154 0.5064 2075797 Maybridge3_001147 Fc1ccc(cc1)C(=O)C2CC2C(=O)c3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E04 compound treatment 974515.0 96100.0 0.2 1058895.0 127000.0 0.29 0.3475 0.9858 2075798 Maybridge3_001148 ClC1(Cl)CC1CSC2=NCCN2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E05 compound treatment 967506.0 89100.0 0.19 1073247.0 141000.0 0.32 0.3601 0.9683 1308755 Maybridge3_001149 Clc1cccc(NC(=O)C2(CC3CC4CC(C3)C2)C4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E06 compound treatment 1161611.0 283000.0 0.6 1171460.0 239000.0 0.54 0.8089 0.9988 2075799 Maybridge3_001150 CSc1nnc(CCCO)n1c2ccc(Cl)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E07 compound treatment 1088631.0 210000.0 0.45 1118571.0 186000.0 0.42 0.6145 0.9997 1680663 Maybridge3_001151 CC1=C(O)C(=O)OC1c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E08 compound treatment 1146821.0 268000.0 0.57 1100657.0 168000.0 0.38 0.6729 0.9813 2075800 Maybridge3_001152 CSc1cc(nn1S(=O)(=O)c2ccc(Cl)cc2)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E09 compound treatment 1072682.0 194000.0 0.41 1075181.0 143000.0 0.32 0.5208 0.9931 2075801 Maybridge3_001153 Cc1nn(cc1c2ccccc2)S(=O)(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E10 compound treatment 1348575.0 470000.0 1.0 1388374.0 456000.0 1.04 1.4379 0.9998 2075802 Maybridge3_001154 Cc1ccnn1c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E11 compound treatment 1076011.0 198000.0 0.42 1389617.0 457000.0 1.04 1.0313 0.9202 1665318 Maybridge3_001155 Cc1cc(NS(=O)(=O)c2cc(Cl)sc2Cl)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E12 compound treatment 1475743.0 597000.0 1.27 1243720.0 311000.0 0.71 1.396 0.9622 2075803 Maybridge3_001156 CS/C(=N\C#N)/NCCC1CC1(Cl)Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E13 compound treatment 1276403.0 398000.0 0.84 1102515.0 170000.0 0.39 0.8702 0.9374 2075804 Maybridge3_001157 OCCCc1[nH]nc(c1Br)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E14 compound treatment 1445322.0 567000.0 1.2 1095323.0 163000.0 0.37 1.1118 0.884 2075805 Maybridge3_001158 O=C1CC(CC(=O)C1)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E15 compound treatment 1073610.0 195000.0 0.41 1139280.0 207000.0 0.47 0.6253 0.998 2075806 Maybridge3_001159 CCc1cnc(N/C=N/O)nc1c2c(F)cccc2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E16 compound treatment 1022373.0 144000.0 0.31 1079169.0 147000.0 0.33 0.4518 0.999 2075807 Maybridge3_001160 CC(C)(C)c1csc(=S)n1CCc2ccccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E17 compound treatment 1146225.0 268000.0 0.57 1186585.0 254000.0 0.58 0.8102 1.0 2075808 Maybridge3_001161 Cc1c(cnn1c2ccccc2)c3ccnc(N)n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E18 compound treatment 1144658.0 266000.0 0.56 1046923.0 115000.0 0.26 0.5833 0.9383 2075809 Maybridge3_001162 CC(NS(=O)(=O)c1cccc(c1)C(F)(F)F)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E19 compound treatment 1098643.0 220000.0 0.47 926905.0 -5480.0 -0.01 0.3214 0.688 2075810 Maybridge3_001163 Clc1cc(C(=O)CSc2ccccn2)c(Cl)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E20 compound treatment 1143656.0 265000.0 0.56 991402.0 59000.0 0.13 0.4925 0.8519 2075811 Maybridge3_001164 COC(=O)c1ccccc1N/C=N/O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E21 compound treatment 968604.0 90200.0 0.19 977308.0 44900.0 0.1 0.2075 0.9568 1413743 Maybridge3_001165 Cc1nn(C)c(C)c1NC(=O)c2ccccc2N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E22 compound treatment 909125.0 30700.0 0.07 1053957.0 122000.0 0.28 0.2415 0.8505 1540816 Maybridge3_001166 CS(=O)(=O)NCc1c(Cl)cccc1Sc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E23 mock treatment 885781.0 7410.0 0.02 937465.0 5080.0 0.01 0.0193 0.9886 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 E24 mock treatment 512324.0 -366000.0 -0.78 852842.0 -79500.0 -0.18 -0.6766 -0.8491 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F01 compound treatment 591670.0 -287000.0 -0.61 508856.0 -424000.0 -0.96 -1.1107 -0.9754 2075812 Maybridge3_001167 Cc1nc(CSc2ccc(Cl)cc2)cs1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F02 compound treatment 825550.0 -52800.0 -0.11 767087.0 -165000.0 -0.38 -0.3449 -0.8796 2075813 Maybridge3_001168 CC(NC(=O)/C=C/c1ccccc1)c2ccc(C)cc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F03 compound treatment 856750.0 -21600.0 -0.05 811558.0 -121000.0 -0.27 -0.2267 -0.8139 1247128 Maybridge3_001169 COC(=O)c1cccc(NC(=O)c2ccc(cc2)C(C)(C)C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F04 compound treatment 860038.0 -18300.0 -0.04 899049.0 -33300.0 -0.08 -0.0811 -0.9519 1200571 Maybridge3_001170 COc1ccc(CCNC(C#N)c2ccco2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F05 compound treatment 852673.0 -25700.0 -0.05 984739.0 52400.0 0.12 0.0456 0.3486 1379769 Maybridge3_001171 CC1N(CCc2sccc12)C(=O)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F06 compound treatment 1474867.0 596000.0 1.26 1224004.0 292000.0 0.66 1.363 0.9546 1504019 Maybridge3_001172 CN(C)c1ccc(c(Cl)c1)c2nc(=O)c3ccccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F07 compound treatment 1187680.0 309000.0 0.66 1028270.0 95900.0 0.22 0.6178 0.8941 1015425 Maybridge3_001173 Cc1ccccc1NC(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F08 compound treatment 1091189.0 213000.0 0.45 1104365.0 172000.0 0.39 0.5955 0.9975 1249585 Maybridge3_001174 CCOC(=O)C(=C1C2CC3CC(C2)CC1C3)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F09 compound treatment 1041557.0 163000.0 0.35 1028504.0 96100.0 0.22 0.3991 0.9755 1632392 Maybridge3_001175 O=C1OCCN=C(c2ccccc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F10 compound treatment 1336060.0 458000.0 0.97 1224335.0 292000.0 0.66 1.1554 0.9829 2075814 Maybridge3_001176 CSc1nc(nc(N)c1c2ccccc2)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F11 compound treatment 1388421.0 510000.0 1.08 1302663.0 370000.0 0.84 1.3599 0.9923 1720841 Maybridge3_001177 Fc1ccccc1n2c(csc2=N)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F12 compound treatment 1576808.0 698000.0 1.48 1134760.0 202000.0 0.46 1.3723 0.8851 2075815 Maybridge3_001178 COC(=O)c1ccccc1NC(=S)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F13 compound treatment 1219068.0 341000.0 0.72 951854.0 19500.0 0.04 0.542 0.749 2075816 Maybridge3_001179 Clc1ccc(cc1)c2ncon2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F14 compound treatment 1447754.0 569000.0 1.21 1270446.0 338000.0 0.77 1.397 0.9762 1629322 Maybridge3_001180 COc1nc-2c(Cc3cc(NC(=O)C)ccc32)c(c4ccco4)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F15 compound treatment 1530354.0 652000.0 1.38 1240434.0 308000.0 0.7 1.4726 0.9504 1482140 Maybridge3_001181 Cc1nc2ccccc2n1C3CC(=O)N(C3=O)c4ccc(F)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F16 compound treatment 1415704.0 537000.0 1.14 1105729.0 173000.0 0.39 1.0842 0.8994 1742113 Maybridge3_001182 Cc1ccc(cc1)C(=O)Nc2nccc(n2)c3ccc4OCCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F17 compound treatment 1062491.0 184000.0 0.39 1159198.0 227000.0 0.52 0.6406 0.9906 1674958 Maybridge3_001183 Clc1ccccc1CC2=NC(=O)C(CC(=O)Nc3ccccc3)S2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F18 compound treatment 1131754.0 253000.0 0.54 999953.0 67600.0 0.15 0.4885 0.8743 2075817 Maybridge3_001184 COC(=O)c1sccc1NC(=O)CSCc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F19 compound treatment 966102.0 87700.0 0.19 1110582.0 178000.0 0.41 0.418 0.9376 2075818 Maybridge3_001185 CC(C)(O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F20 compound treatment 1089835.0 211000.0 0.45 991500.0 59100.0 0.13 0.412 0.8804 2075819 Maybridge3_001186 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2nnc(o2)N3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F21 compound treatment 1399317.0 521000.0 1.1 1099086.0 167000.0 0.38 1.0489 0.8983 2075820 Maybridge3_001187 FC(F)(F)c1cccc(c1)c2nnc(o2)c3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F22 compound treatment 1302040.0 424000.0 0.9 966597.0 34200.0 0.08 0.6901 0.7655 2075821 Maybridge3_001188 Nc1ncc(c2nc3ccccc3s2)c(N)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F23 mock treatment 875455.0 -2920.0 -0.01 1020485.0 88100.0 0.2 0.1373 0.6849 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 F24 mock treatment 735999.0 -142000.0 -0.3 733365.0 -199000.0 -0.45 -0.5334 -0.9806 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G01 compound treatment 1066035.0 188000.0 0.4 1017982.0 85600.0 0.19 0.4189 0.9459 2075822 Maybridge3_001189 CN(c1cccc(F)c1C#N)n2c(C)ccc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G02 compound treatment 1017194.0 139000.0 0.29 995343.0 63000.0 0.14 0.3093 0.9452 2075823 Maybridge3_001190 c1coc(c1)c2nccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G03 compound treatment 988571.0 110000.0 0.23 1014058.0 81700.0 0.19 0.2965 0.9935 2075824 Maybridge3_001191 CSCC(CSC)OC(=O)Nc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G04 compound treatment 877298.0 -1080.0 0.0 1198587.0 266000.0 0.61 0.4263 0.7044 1621848 Maybridge3_001192 Clc1ccc(cc1)S(=O)(=O)NC2CCSC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G05 compound treatment 1164930.0 287000.0 0.61 1132686.0 200000.0 0.46 0.7516 0.9899 2075825 Maybridge3_001193 Cc1cc(Cl)cc2S/C(=C/c3cccnc3)/C(=O)c21 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G06 compound treatment 1249889.0 372000.0 0.79 1493733.0 561000.0 1.28 1.4594 0.9731 1156701 Maybridge3_001194 Fc1c(cccc1C(=O)Oc2ccccc2)C(=O)Oc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G07 compound treatment 1109701.0 231000.0 0.49 1134277.0 202000.0 0.46 0.6713 0.9995 2075826 Maybridge3_001195 Cc1cc(no1)n2c(C)ccc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G08 compound treatment 1632969.0 755000.0 1.6 1522898.0 591000.0 1.34 2.0805 0.9962 2075827 Maybridge3_001196 O/N=C/c1ccc(o1)c2ccc(F)cc2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G09 compound treatment 1223465.0 345000.0 0.73 1496865.0 564000.0 1.28 1.4248 0.9645 2075828 Maybridge3_001197 O/N=C/NC1=C(C(=O)c2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G10 compound treatment 1159638.0 281000.0 0.6 1743618.0 811000.0 1.84 1.7258 0.8903 1238271 Maybridge3_001198 Cn1cccc1C2=C(C#N)C(C(=C(N)O2)C#N)c3c(Cl)cccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G11 compound treatment 1541174.0 663000.0 1.41 1260344.0 328000.0 0.75 1.5208 0.9561 1441863 Maybridge3_001199 Clc1cc(c(Cl)s1)S(=O)(=O)Nc2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G12 compound treatment 1283903.0 406000.0 0.86 1503011.0 571000.0 1.3 1.5253 0.98 2075829 Maybridge3_001200 ClC1(Cl)CC1CCNS(=O)(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G13 compound treatment 906835.0 28500.0 0.06 1221820.0 289000.0 0.66 0.508 0.7687 2075830 Maybridge3_001201 CNC(=O)n1cc(C)c(n1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G14 compound treatment 1181204.0 303000.0 0.64 1470449.0 538000.0 1.22 1.319 0.9547 2075831 Maybridge3_001202 CS(=O)(=O)N(CCc1ccc(Cl)cc1)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G15 compound treatment 1381271.0 503000.0 1.07 1533973.0 602000.0 1.37 1.721 0.9924 2075832 Maybridge3_001203 Cc1cn(nc1c2cccs2)C(=O)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G16 compound treatment 1362475.0 484000.0 1.03 1306570.0 374000.0 0.85 1.3272 0.9957 2075833 Maybridge3_001204 Clc1ccc(cc1)c2cc(=O)[nH]c(=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G17 compound treatment 1535643.0 657000.0 1.39 1998943.0 1070000.0 2.42 2.6999 0.9654 2075834 Maybridge3_001205 Cc1n[nH]cc1c2nc(no2)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G18 compound treatment 1554927.0 677000.0 1.43 1332953.0 401000.0 0.91 1.6581 0.976 2075835 Maybridge3_001206 Clc1ccc(cc1)C2CC(=O)C=C(C2)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G19 compound treatment 1523202.0 645000.0 1.37 1285249.0 353000.0 0.8 1.5339 0.9677 2075836 Maybridge3_001207 Cc1nn(C)c(C)c1NS(=O)(=O)c2cc(C)c(Cl)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G20 compound treatment 1287741.0 409000.0 0.87 1238469.0 306000.0 0.7 1.1057 0.994 2075837 Maybridge3_001208 CN(NC1OC(=O)c2ccccc12)c3cc(cc(C)n3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G21 compound treatment 1329109.0 451000.0 0.96 1107312.0 175000.0 0.4 0.9569 0.9245 2075838 Maybridge3_001209 O/N=C/NC1CCCCNC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G22 compound treatment 1323360.0 445000.0 0.94 1095050.0 163000.0 0.37 0.9286 0.9164 2075839 Maybridge3_001210 CC(=O)NCc1c(Cl)cccc1Sc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G23 mock treatment 1089802.0 211000.0 0.45 1114174.0 182000.0 0.41 0.6092 0.9992 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 G24 mock treatment 736552.0 -142000.0 -0.3 934008.0 1630.0 0.0 -0.21 -0.6984 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H01 compound treatment 958469.0 80100.0 0.17 888277.0 -44100.0 -0.1 0.0492 0.2493 2075840 Maybridge3_001211 CC(C)(C)n1ccc(n1)c2cc(F)cc(F)c2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H02 compound treatment 1152486.0 274000.0 0.58 909674.0 -22700.0 -0.05 0.3744 0.6418 1084493 Maybridge3_001212 Cc1c(C#N)c(N)sc1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H03 compound treatment 1026335.0 148000.0 0.31 877659.0 -54700.0 -0.12 0.1338 0.3966 2075841 Maybridge3_001213 COC(=O)c1cccc(NC(=O)C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H04 compound treatment 950303.0 71900.0 0.15 912356.0 -20000.0 -0.05 0.0756 0.4752 1591706 Maybridge3_001214 COc1ccc(CCNC(C#N)c2cc(Br)ccc2O)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H05 compound treatment 934567.0 56200.0 0.12 1085504.0 153000.0 0.35 0.3304 0.898 2075842 Maybridge3_001215 COC(=O)c1cccc(NS(=O)(=O)c2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H06 compound treatment 1259910.0 382000.0 0.81 880109.0 -52300.0 -0.12 0.4879 0.5968 1577664 Maybridge3_001216 Oc1ccc(Br)cc1CNc2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H07 compound treatment 1518539.0 640000.0 1.36 1107088.0 175000.0 0.4 1.2405 0.8773 2075843 Maybridge3_001217 CCOC(=O)/C(=C\1/C(=O)Nc2ccc(Br)cc12)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H08 compound treatment 1098870.0 220000.0 0.47 1200141.0 268000.0 0.61 0.761 0.9915 1340707 Maybridge3_001218 Cc1noc(N2C(=O)C3C4CC(C=C4)C3C2=O)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H09 compound treatment 1803622.0 925000.0 1.96 1388588.0 456000.0 1.04 2.1204 0.9556 1002388 Maybridge3_001219 O=C(CSC#N)c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H10 compound treatment 1305390.0 427000.0 0.91 1212660.0 280000.0 0.64 1.0907 0.9852 2075844 Maybridge3_001220 COC(=O)c1cc2c(C)nn(C)c2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H11 compound treatment 1372227.0 494000.0 1.05 1535954.0 604000.0 1.37 1.7106 0.9911 1713070 Maybridge3_001221 CSc1cccc(c1)n2c(csc2=N)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H12 compound treatment 1642278.0 764000.0 1.62 1430762.0 498000.0 1.13 1.9463 0.9847 2075845 Maybridge3_001222 Clc1ccccc1SC(=O)Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H13 compound treatment 1849707.0 971000.0 2.06 861069.0 -71300.0 -0.16 1.3414 0.6494 2075846 Maybridge3_001223 Clc1ccc2OC(Nc2c1)c3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H14 compound treatment 1012592.0 134000.0 0.28 1654448.0 722000.0 1.64 1.362 0.8175 1544404 Maybridge3_001224 Cc1ccc2N=C(CC(=O)Nc2c1C)c3ccccc3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H15 compound treatment 1887861.0 1010000.0 2.14 1417849.0 485000.0 1.1 2.2937 0.9526 2075847 Maybridge3_001225 CSC1=NCCCN1S(=O)(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H16 compound treatment 1798089.0 920000.0 1.95 1500446.0 568000.0 1.29 2.2919 0.98 2075848 Maybridge3_001226 N/C(=C(\N=C\c1ccc(Cl)cc1)/C#N)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H17 compound treatment 1024626.0 146000.0 0.31 1279759.0 347000.0 0.79 0.7777 0.9166 1151352 Maybridge3_001227 CN(C)c1ccc(cc1)C2Nc3ccc(C)cc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H18 compound treatment 1069289.0 191000.0 0.4 1424824.0 492000.0 1.12 1.0779 0.9054 2075849 Maybridge3_001228 CCOC(=O)c1c(C)csc1NC(=O)CSc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H19 compound treatment 1790503.0 912000.0 1.93 1400477.0 468000.0 1.06 2.1198 0.9604 1393284 Maybridge3_001229 Clc1ccc(cc1)C(=C)NCc2ccncc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H20 compound treatment 1350912.0 473000.0 1.0 1156170.0 224000.0 0.51 1.0681 0.9507 2075850 Maybridge3_001230 CSc1nc(=O)c2sccc2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H21 compound treatment 1445254.0 567000.0 1.2 1177697.0 245000.0 0.56 1.2441 0.9391 2075851 Maybridge3_001231 Cc1ccc(c2nnc(o2)c3ccncc3)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H22 compound treatment 1406859.0 528000.0 1.12 1086280.0 154000.0 0.35 1.0396 0.8857 2075852 Maybridge3_001232 NC(=O)c1sccc1NS(=O)(=O)c2ccc(Cl)c(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H23 mock treatment 1319505.0 441000.0 0.94 1096684.0 164000.0 0.37 0.9254 0.919 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 H24 mock treatment 802580.0 -75800.0 -0.16 885197.0 -47200.0 -0.11 -0.1895 -0.9807 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I01 compound treatment 1077362.0 199000.0 0.42 1030776.0 98400.0 0.22 0.4565 0.956 1091165 Maybridge3_001233 Cc1onc(c1C(=O)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I02 compound treatment 1144287.0 266000.0 0.56 1062210.0 130000.0 0.3 0.6073 0.9544 2075853 Maybridge3_001234 Cc1nn(C)c(Cl)c1S(=O)(=O)Nc2ccc(Br)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I03 compound treatment 1076283.0 198000.0 0.42 1183911.0 252000.0 0.57 0.701 0.9884 2075854 Maybridge3_001235 O/N=C(\NCCc1ccncc1)/C(c2ccccc2)c3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I04 compound treatment 1289266.0 411000.0 0.87 1219457.0 287000.0 0.65 1.0775 0.9899 2075855 Maybridge3_001236 Clc1cccc(c1)C(=O)NC2CCSC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I05 compound treatment 1406450.0 528000.0 1.12 1185880.0 253000.0 0.58 1.1991 0.9523 2075856 Maybridge3_001237 CC(C)(COC(=O)Nc1ccc(Cl)cc1)n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I06 compound treatment 1278455.0 400000.0 0.85 1419280.0 487000.0 1.11 1.3825 0.9914 1340148 Maybridge3_001238 Fc1c(cccc1C(=O)N2CCCCC2)C(=O)N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I07 compound treatment 1220289.0 342000.0 0.72 1353584.0 421000.0 0.96 1.1897 0.9906 1231777 Maybridge3_001239 Cc1cc(NC(=O)CC#N)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I08 compound treatment 1360135.0 482000.0 1.02 1556781.0 624000.0 1.42 1.726 0.9869 2075857 Maybridge3_001240 Fc1ccc(cc1)C(=O)NCc2ccc(cc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I09 compound treatment 1455293.0 577000.0 1.22 1354425.0 422000.0 0.96 1.5433 0.9928 2075858 Maybridge3_001241 CSc1ccccc1NC(=O)c2cc(Cl)sc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I10 compound treatment 1754596.0 876000.0 1.86 1375489.0 443000.0 1.01 2.0258 0.9587 2075859 Maybridge3_001242 CS(=O)(=O)Nc1cc(NS(=O)(=O)C)cc(c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I11 compound treatment 1335905.0 458000.0 0.97 1241293.0 309000.0 0.7 1.1825 0.9874 1657518 Maybridge3_001243 O=C(Nc1ccccc1Oc2ccccc2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I12 compound treatment 1447086.0 569000.0 1.21 1071424.0 139000.0 0.32 1.076 0.8633 1464788 Maybridge3_001244 CS(=O)(=O)Nc1ccc(Oc2c(C#N)cccc2C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I13 compound treatment 1087798.0 209000.0 0.44 1520004.0 588000.0 1.34 1.2586 0.894 1235084 Maybridge3_001245 CN(C)c1cccc(N(C)C)c1CNS(=O)(=O)c2cc(Cl)sc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I14 compound treatment 1466429.0 588000.0 1.25 1832925.0 901000.0 2.05 2.3293 0.9717 2075860 Maybridge3_001246 NS(=O)(=O)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I15 compound treatment 1451075.0 573000.0 1.21 1430742.0 498000.0 1.13 1.6597 0.9994 2075861 Maybridge3_001247 Cc1nc(C)c(s1)c2ccnc(N)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I16 compound treatment 1284595.0 406000.0 0.86 1882531.0 950000.0 2.16 2.1364 0.9187 1459848 Maybridge3_001248 CSc1nnc(SC2=CC(=O)CC(C2)c3ccccc3)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I17 compound treatment 1377649.0 499000.0 1.06 1591141.0 659000.0 1.5 1.8075 0.9856 1511153 Maybridge3_001249 Cc1nc(C)c(s1)c2cnc(NS(=O)(=O)c3ccc(Cl)cc3)nc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I18 compound treatment 1499568.0 621000.0 1.32 1714370.0 782000.0 1.78 2.1883 0.9891 2075862 Maybridge3_001250 CS/C(=N/C#N)/NCc1c(Cl)cccc1Oc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I19 compound treatment 1484693.0 606000.0 1.29 1434547.0 502000.0 1.14 1.7162 0.9983 1613492 Maybridge3_001251 CN(C1CC2CC1C=C2)S(=O)(=O)c3cc(Cl)sc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I20 compound treatment 1252568.0 374000.0 0.79 1532574.0 600000.0 1.36 1.5258 0.9667 2075863 Maybridge3_001252 Cc1cc(cc(n1)n2cc(C#N)c(N)n2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I21 compound treatment 1152341.0 274000.0 0.58 1407242.0 475000.0 1.08 1.1741 0.9577 1646441 Maybridge3_001253 Clc1cccc(NC2CCCCNC2=O)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I22 compound treatment 1278612.0 400000.0 0.85 1236638.0 304000.0 0.69 1.0891 0.9949 1521899 Maybridge3_001254 CC(=O)N1CCC(CC1)NC(=O)Oc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I23 mock treatment 1098081.0 220000.0 0.47 1204467.0 272000.0 0.62 0.7668 0.9902 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 I24 mock treatment 739059.0 -139000.0 -0.3 1035408.0 103000.0 0.23 -0.0432 -0.1146 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J01 compound treatment 992098.0 114000.0 0.24 947070.0 14700.0 0.03 0.1941 0.7974 1637576 Maybridge3_001255 CC(C)N1CCS(=O)(=O)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J02 compound treatment 1000607.0 122000.0 0.26 990368.0 58000.0 0.13 0.2765 0.9509 1297552 Maybridge3_001256 COc1cc(cc(OC)c1OC)C(=O)NC(C)(C)CCO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J03 compound treatment 1094966.0 217000.0 0.46 913928.0 -18500.0 -0.04 0.295 0.6398 1728518 Maybridge3_001257 COC(=O)c1cccc(NC(=O)C(C)(C)C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J04 compound treatment 901649.0 23300.0 0.05 1169962.0 238000.0 0.54 0.4168 0.7685 1722497 Maybridge3_001258 Brc1ccc(cc1)S(=O)(=O)N(CCC#N)C2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J05 compound treatment 1058639.0 180000.0 0.38 1168109.0 236000.0 0.54 0.6492 0.9863 1211575 Maybridge3_001259 COC(=O)c1cccc(NS(=O)(=O)C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J06 compound treatment 1682308.0 804000.0 1.7 1395060.0 463000.0 1.05 1.9489 0.9731 1680927 Maybridge3_001260 N#CCc1ccc(NC2(CCCC2)C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J07 compound treatment 1601403.0 723000.0 1.53 1898656.0 966000.0 2.2 2.6373 0.9845 1729902 Maybridge3_001261 Oc1nnc(c2ccc(Cl)cc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J08 compound treatment 1825890.0 948000.0 2.01 1574744.0 642000.0 1.46 2.453 0.9877 2075864 Maybridge3_001262 CS/C(=N\C(=O)c1c(Cl)cccc1Cl)/NCc2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J09 compound treatment 1688101.0 810000.0 1.72 1600008.0 668000.0 1.52 2.2871 0.9981 1244183 Maybridge3_001263 Clc1ccc(c(Cl)c1)n2c(csc2=N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J10 compound treatment 1710431.0 832000.0 1.76 1430013.0 498000.0 1.13 2.0473 0.977 2075865 Maybridge3_001264 CSC(=CC(=O)c1cccs1)SC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J11 compound treatment 1790160.0 912000.0 1.93 1460483.0 528000.0 1.2 2.2158 0.9738 1718424 Maybridge3_001265 CN1C(=O)CN(C2CCCCC2)C(=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J12 compound treatment 1843666.0 965000.0 2.05 1785023.0 853000.0 1.94 2.8177 0.9996 2075866 Maybridge3_001266 CNC(=O)Sc1ccccc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J13 compound treatment 1631768.0 753000.0 1.6 1545759.0 613000.0 1.39 2.1155 0.9977 2075867 Maybridge3_001267 Clc1ccc(cc1)C2Nc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J14 compound treatment 1861344.0 983000.0 2.08 1362475.0 430000.0 0.98 2.1649 0.9405 2075868 Maybridge3_001268 O=C1ON=C(C1C=C2CCCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J15 compound treatment 1758131.0 880000.0 1.87 1417214.0 485000.0 1.1 2.0982 0.9685 1290526 Maybridge3_001269 Clc1ccccc1c2csc(n2)c3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J16 compound treatment 1795806.0 917000.0 1.94 1896901.0 965000.0 2.19 2.9259 0.9982 2075869 Maybridge3_001270 N/C(=C(\N=C\c1ccc(cc1)C(F)(F)F)/C#N)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J17 compound treatment 1526245.0 648000.0 1.37 1363070.0 431000.0 0.98 1.6636 0.9862 1175688 Maybridge3_001271 COc1ccc(cc1OC)C2Nc3cc(C)ccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J18 compound treatment 2144373.0 1270000.0 2.68 1625854.0 693000.0 1.58 3.0126 0.9679 2075870 Maybridge3_001272 Cc1csc(NC(=O)C(F)(F)F)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J19 compound treatment 1394118.0 516000.0 1.09 1613301.0 681000.0 1.55 1.8678 0.9855 1527880 Maybridge3_001273 Clc1ccccc1c2nc3ccccc3c(=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J20 compound treatment 1344359.0 466000.0 0.99 1387392.0 455000.0 1.03 1.43 0.9997 2075871 Maybridge3_001274 Cn1cc(Br)c(NS(=O)(=O)c2ccccc2C(F)(F)F)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J21 compound treatment 1196873.0 318000.0 0.68 1303061.0 371000.0 0.84 1.0734 0.994 2075872 Maybridge3_001275 Oc1ccccc1/C=N/c2ccc(c(Cl)c2)S(=O)(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J22 compound treatment 1457880.0 580000.0 1.23 1290496.0 358000.0 0.81 1.4444 0.98 2075873 Maybridge3_001276 COC(=O)/C(=C\1/CCSC1)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J23 mock treatment 1227295.0 349000.0 0.74 1131420.0 199000.0 0.45 0.843 0.9722 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 J24 mock treatment 806235.0 -72100.0 -0.15 575276.0 -357000.0 -0.81 -0.6822 -0.8258 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K01 compound treatment 1037840.0 159000.0 0.34 727925.0 -204000.0 -0.46 -0.0896 -0.156 2075874 Maybridge3_001277 Nc1nnc(SCc2c(nnn2c3ccc(F)cc3F)c4ccccc4)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K02 compound treatment 983254.0 105000.0 0.22 908203.0 -24200.0 -0.05 0.1183 0.5167 1228040 Maybridge3_001278 NC(=O)C1CCN(CC1)c2cccc(Cl)c2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K03 compound treatment 1052583.0 174000.0 0.37 977018.0 44600.0 0.1 0.3329 0.8692 2075875 Maybridge3_001279 NC(=O)c1ccccc1Oc2ccc(Cl)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K04 compound treatment 1033016.0 155000.0 0.33 986976.0 54600.0 0.12 0.3196 0.9117 2075876 Maybridge3_001280 Cc1cnnn1c2c(C)nn(C)c2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K05 compound treatment 1118444.0 240000.0 0.51 1128340.0 196000.0 0.45 0.6749 0.9978 1420885 Maybridge3_001281 Fc1c(CN2CCOCC2)cccc1CN3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K06 compound treatment 1190008.0 312000.0 0.66 1128369.0 196000.0 0.45 0.7822 0.9816 2075877 Maybridge3_001282 Cc1c(nnn1c2cc(Cl)ccc2Cl)c3ccn[nH]3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K07 compound treatment 1205687.0 327000.0 0.69 1151861.0 219000.0 0.5 0.8435 0.9869 2075878 Maybridge3_001283 c1cc(n[nH]1)c2cc3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K08 compound treatment 1210984.0 333000.0 0.71 1053365.0 121000.0 0.28 0.6931 0.9157 2075879 Maybridge3_001284 Fc1ccc(c2ccc(CNC(=O)c3ccccc3)o2)c(F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K09 compound treatment 1204300.0 326000.0 0.69 1224268.0 292000.0 0.66 0.9578 0.9998 2075880 Maybridge3_001285 Clc1cc(c(Cl)s1)S(=O)(=O)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K10 compound treatment 1062952.0 185000.0 0.39 1362888.0 431000.0 0.98 0.9688 0.9191 1174817 Maybridge3_001286 Cn1cccc1C2=C(C#N)C(C(=C(N)O2)C#N)c3ccc(C#N)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K11 compound treatment 1469118.0 591000.0 1.25 1358303.0 426000.0 0.97 1.5703 0.9919 1525251 Maybridge3_001287 Clc1sc(Cl)c(c1Br)S(=O)(=O)N2CCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K12 compound treatment 958326.0 80000.0 0.17 1363469.0 431000.0 0.98 0.8129 0.8173 2075881 Maybridge3_001288 CSc1cc(nn1C(=O)Nc2ccccc2)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K13 compound treatment 1089144.0 211000.0 0.45 1352331.0 420000.0 0.95 0.9911 0.9402 1434021 Maybridge3_001289 CSc1nc(NS(=O)(=O)c2ccc(F)cc2F)nn1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K14 compound treatment 1106090.0 228000.0 0.48 1667946.0 736000.0 1.67 1.5239 0.8755 2075882 Maybridge3_001290 Fc1ccc(NC(=O)CSc2ccccn2)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K15 compound treatment 1201910.0 324000.0 0.69 1417203.0 485000.0 1.1 1.2644 0.9739 2075883 Maybridge3_001291 Cc1nc(C)c(s1)c2ccnc(N/C=N/O)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K16 compound treatment 1180518.0 302000.0 0.64 1555974.0 624000.0 1.42 1.4554 0.9355 2075884 Maybridge3_001292 NC(=O)CC(=O)c1ccc(F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K17 compound treatment 1236977.0 359000.0 0.76 1357498.0 425000.0 0.97 1.221 0.9929 2075885 Maybridge3_001293 Cc1c(cnn1c2ccccc2)c3ccnn3C(=O)Nc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K18 compound treatment 1324037.0 446000.0 0.94 1704358.0 772000.0 1.76 1.9091 0.9578 1638955 Maybridge3_001294 Nc1n[nH]c(NCc2c(Cl)cccc2Oc3ccccc3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K19 compound treatment 1394612.0 516000.0 1.09 1689377.0 757000.0 1.72 1.9908 0.9761 1124837 Maybridge3_001295 CCc1c(CC)c(sc1C#N)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K20 compound treatment 1169389.0 291000.0 0.62 1542240.0 610000.0 1.39 1.4167 0.9335 1471850 Maybridge3_001296 O(c1ccccc1)c2ccc(cc2)c3ccn[nH]3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K21 compound treatment 1191522.0 313000.0 0.66 1357706.0 425000.0 0.97 1.1532 0.9832 1730052 Maybridge3_001297 Cc1nn(C)c(C)c1NC(=O)c2ccccc2NC(=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K22 compound treatment 1216842.0 338000.0 0.72 1387621.0 455000.0 1.04 1.2392 0.984 1391203 Maybridge3_001298 CSC(=CC(=O)c1ccc(Oc2ccccc2)cc1)SC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K23 mock treatment 1165688.0 287000.0 0.61 1222330.0 290000.0 0.66 0.8968 0.9992 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 K24 mock treatment 782774.0 -95600.0 -0.2 746979.0 -185000.0 -0.42 -0.4414 -0.9437 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L01 compound treatment 721504.0 -157000.0 -0.33 635368.0 -297000.0 -0.68 -0.7126 -0.9468 2075886 Maybridge3_001299 Nc1ccc(cc1)c2cnco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L02 compound treatment 750821.0 -128000.0 -0.27 873084.0 -59300.0 -0.13 -0.2865 -0.9483 2075887 Maybridge3_001300 CNC(=O)c1ccc(/C=C/2\N3CCC(CC3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L03 compound treatment 876224.0 -2150.0 0.0 942776.0 10400.0 0.02 0.0135 0.5603 1331061 Maybridge3_001301 COC(=O)c1cccc(NC(=O)C2CC2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L04 compound treatment 190155.0 -688000.0 -1.46 136269.0 -796000.0 -1.81 -2.3115 -0.9943 2075888 Maybridge3_001302 NC1=Nc2ccc(Cl)cc2C1(O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L05 compound treatment 1014549.0 136000.0 0.29 1181413.0 249000.0 0.57 0.6045 0.9511 2075889 Maybridge3_001303 CC1N(CCc2sccc12)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L06 compound treatment 853125.0 -25300.0 -0.05 968255.0 35900.0 0.08 0.0198 0.2032 2075890 Maybridge3_001304 COc1cc(NC(=O)/C=C/c2ccccc2Cl)c(OC)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L07 compound treatment 1145275.0 267000.0 0.57 1142980.0 211000.0 0.48 0.7387 0.9965 1446051 Maybridge3_001305 O=C(Nc1ccccc1C(=O)Nc2ccccn2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L08 compound treatment 1232022.0 354000.0 0.75 1134464.0 202000.0 0.46 0.855 0.9724 1539708 Maybridge3_001306 CC(=O)Nc1ccc(cc1)C(=O)CCC#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L09 compound treatment 1389722.0 511000.0 1.08 1238127.0 306000.0 0.7 1.2581 0.9769 2075891 Maybridge3_001307 Cc1c(C)c(C)c(CS/C(=N/N)/N)c(C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L10 compound treatment 1263007.0 385000.0 0.82 1362795.0 430000.0 0.98 1.2685 0.9959 2075892 Maybridge3_001308 CCOc1cc(nc(N)n1)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L11 compound treatment 1523205.0 645000.0 1.37 1412752.0 480000.0 1.09 1.7389 0.9938 1265243 Maybridge3_001309 COc1ccc(cc1OC)n2c(csc2=N)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L12 compound treatment 1520015.0 642000.0 1.36 1485146.0 553000.0 1.26 1.8505 0.9992 2075893 Maybridge3_001310 CSc1cc(nc(c1)c2ccc(Cl)cc2)c3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L13 compound treatment 1512820.0 634000.0 1.34 1553811.0 621000.0 1.41 1.9501 0.9997 2075894 Maybridge3_001311 COc1ccc(cc1)c2noc(CCC(=O)O)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L14 compound treatment 1528272.0 650000.0 1.38 1293026.0 361000.0 0.82 1.554 0.9693 1413345 Maybridge3_001312 COc1ccc2OC(=C(C#N)C(C(C#N)C#N)c2c1)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L15 compound treatment 1497458.0 619000.0 1.31 1333494.0 401000.0 0.91 1.5729 0.9842 2075895 Maybridge3_001313 Cc1nc(cs1)c2ccccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L16 compound treatment 1541025.0 663000.0 1.4 1299323.0 367000.0 0.83 1.5832 0.969 1496287 Maybridge3_001314 Cc1cc(Cl)ccc1OCC2NCCS2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L17 compound treatment 1243749.0 365000.0 0.77 1246338.0 314000.0 0.71 1.0524 0.9992 1209869 Maybridge3_001315 CC(=O)Nc1ccc(cc1)C2Nc3ccc(C)cc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L18 compound treatment 1408534.0 530000.0 1.12 1169582.0 237000.0 0.54 1.1761 0.9434 2075896 Maybridge3_001316 Cc1csc(NC(=O)C(F)(F)F)c1C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L19 compound treatment 1319863.0 441000.0 0.94 1296773.0 364000.0 0.83 1.2476 0.9981 1639375 Maybridge3_001317 Clc1cc(NC(=O)c2ccccc2)ccc1N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L20 compound treatment 1440956.0 563000.0 1.19 1475815.0 543000.0 1.24 1.717 0.9998 2075897 Maybridge3_001318 CCOC(=O)CC(=O)Nc1ccn(C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L21 compound treatment 1482026.0 604000.0 1.28 1265475.0 333000.0 0.76 1.4404 0.9687 2075898 Maybridge3_001319 Oc1ccc(Cl)cc1/C=N/Cc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L22 compound treatment 1384890.0 507000.0 1.07 1370114.0 438000.0 1.0 1.463 0.9993 1577472 Maybridge3_001320 CCOC(=O)CC(=O)Nc1ccsc1C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L23 mock treatment 1249469.0 371000.0 0.79 1191835.0 259000.0 0.59 0.9734 0.9899 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 L24 mock treatment 581239.0 -297000.0 -0.63 897303.0 -35100.0 -0.08 -0.5018 -0.7903 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M01 compound treatment 814848.0 -63500.0 -0.13 866602.0 -65800.0 -0.15 -0.201 -0.9986 1492038 Maybridge3_001321 CC(C)(C)C(=O)CSc1nc(N)c(s1)C(=O)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M02 compound treatment 1073603.0 195000.0 0.41 1050308.0 118000.0 0.27 0.4822 0.9779 2075899 Maybridge3_001322 c1cc([nH]n1)c2ccsc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M03 compound treatment 1082578.0 204000.0 0.43 1075264.0 143000.0 0.32 0.5358 0.99 1674378 Maybridge3_001323 Fc1ccc(NC(=O)C2(CC3CC4CC(C3)C2)C4)c(F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M04 compound treatment 1228554.0 350000.0 0.74 1229867.0 297000.0 0.68 1.0032 0.9989 1467781 Maybridge3_001324 Clc1cccc(c1)C(=O)Nc2ccccc2C(=O)NC3CCSC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M05 compound treatment 1352540.0 474000.0 1.01 1320535.0 388000.0 0.88 1.3348 0.9979 2075900 Maybridge3_001325 CCOC(=O)c1sc2cccc(Cl)c2c1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M06 compound treatment 1328717.0 450000.0 0.95 1376504.0 444000.0 1.01 1.3891 0.9996 2075901 Maybridge3_001326 CS/C(=N\S(=O)(=O)/C=C/c1ccccc1)/NN 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M07 compound treatment 1316563.0 438000.0 0.93 1312773.0 380000.0 0.86 1.2684 0.9994 2075902 Maybridge3_001327 CSCC(=O)Nc1cc(C)on1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M08 compound treatment 1362291.0 484000.0 1.03 1159108.0 227000.0 0.52 1.0899 0.9493 1605779 Maybridge3_001328 Cc1onc(c1C(=O)NCc2cc(Cl)cc(Cl)c2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M09 compound treatment 1193500.0 315000.0 0.67 1203433.0 271000.0 0.62 0.9081 0.9992 1315742 Maybridge3_001329 CN(C)c1cccc(N(C)C)c1CNC(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M10 compound treatment 980079.0 102000.0 0.22 1112003.0 180000.0 0.41 0.4412 0.9554 2075903 Maybridge3_001330 Fc1ccc(c2ccc(C#N)o2)c(F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M11 compound treatment 1136698.0 258000.0 0.55 1197948.0 266000.0 0.6 0.8142 0.9988 1600433 Maybridge3_001331 O=C(Nc1ccccc1)Oc2cccc(c2)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M12 compound treatment 1399170.0 521000.0 1.1 1339475.0 407000.0 0.93 1.4351 0.9962 2075904 Maybridge3_001332 Cc1ccc(cn1)c2ccn[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M13 compound treatment 1188228.0 310000.0 0.66 1298993.0 367000.0 0.83 1.0539 0.9931 1583981 Maybridge3_001333 CN(C)c1cccc(N(C)C)c1CNC(=O)c2ccccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M14 compound treatment 1109370.0 231000.0 0.49 892678.0 -39700.0 -0.09 0.2824 0.5672 2075905 Maybridge3_001334 CSCC(=O)Nc1ccc(F)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M15 compound treatment 1012758.0 134000.0 0.28 1182165.0 250000.0 0.57 0.603 0.9491 2075906 Maybridge3_001335 Cc1nc(C)c(s1)c2ccnc(n2)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M16 compound treatment 1058737.0 180000.0 0.38 1149510.0 217000.0 0.49 0.6194 0.992 1207118 Maybridge3_001336 CS(=O)(=O)n1nccc1c2ccc(Oc3cccc(Cl)c3C#N)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M17 compound treatment 1186428.0 308000.0 0.65 1161005.0 229000.0 0.52 0.8293 0.9936 2075907 Maybridge3_001337 CS/C(=N/S(=O)(=O)c1ccccc1)/NCc2c(cccc2N(C)C)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M18 compound treatment 907482.0 29100.0 0.06 1217241.0 285000.0 0.65 0.5016 0.771 2075908 Maybridge3_001338 CC(=O)OC1=CC(=O)CC(C1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M19 compound treatment 1082863.0 204000.0 0.43 1348152.0 416000.0 0.95 0.9749 0.9375 1151169 Maybridge3_001339 COC(CNc1cccc(Cl)c1C#N)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M20 compound treatment 1306307.0 428000.0 0.91 1321887.0 390000.0 0.89 1.2677 0.9999 1187428 Maybridge3_001340 CC(C)(C)c1ccc(cc1)C(=O)CC(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M21 compound treatment 1152871.0 274000.0 0.58 1191576.0 259000.0 0.59 0.8282 1.0 2075909 Maybridge3_001341 CC1SCC(CS1)NC(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M22 compound treatment 1098645.0 220000.0 0.47 1151913.0 220000.0 0.5 0.6831 0.9994 2075910 Maybridge3_001342 Nc1nccc(n1)c2cccc(Cl)c2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M23 mock treatment 1033270.0 155000.0 0.33 1206786.0 274000.0 0.62 0.6733 0.9551 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 M24 mock treatment 995399.0 117000.0 0.25 908829.0 -23600.0 -0.05 0.1376 0.542 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N01 compound treatment 617237.0 -261000.0 -0.55 605866.0 -327000.0 -0.74 -0.9164 -0.9896 1119590 Maybridge3_001343 Oc1ccccc1c2cncn2Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N02 compound treatment 897385.0 19000.0 0.04 1069973.0 138000.0 0.31 0.2497 0.7917 2075911 Maybridge3_001344 CCOC(=O)c1ccc(/N=C\2/NC3(CCCCC3)C(=C)S2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N03 compound treatment 979125.0 101000.0 0.21 1074256.0 142000.0 0.32 0.3791 0.98 2075912 Maybridge3_001345 CCC(=O)Nc1cccc(c1)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N04 compound treatment 918878.0 40500.0 0.09 1191527.0 259000.0 0.59 0.4773 0.8017 1315287 Maybridge3_001346 COc1cc(cc(OC)c1OC)c2nc3ccccc3c(=O)[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N05 compound treatment 991701.0 113000.0 0.24 1174217.0 242000.0 0.55 0.5587 0.9311 1514026 Maybridge3_001347 CC1N(CCc2sccc12)S(=O)(=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N06 compound treatment 1335791.0 457000.0 0.97 1314950.0 383000.0 0.87 1.3007 0.9985 2075913 Maybridge3_001348 O=c1nc([nH]c2ccccc12)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N07 compound treatment 1265707.0 387000.0 0.82 1220984.0 289000.0 0.66 1.0446 0.9938 1732031 Maybridge3_001349 O=C(Nc1ccccc1C(=O)Nc2cccnc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N08 compound treatment 1297667.0 419000.0 0.89 1395839.0 463000.0 1.05 1.3736 0.9964 1287544 Maybridge3_001350 COc1ccc(cc1)C(=C(SC)SC)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N09 compound treatment 1162328.0 284000.0 0.6 1155267.0 223000.0 0.51 0.784 0.9963 2075914 Maybridge3_001351 N/N=C(\N)/SCc1ccc(C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N10 compound treatment 1217287.0 339000.0 0.72 1508977.0 577000.0 1.31 1.435 0.9599 1230204 Maybridge3_001352 CCOc1cc(nc(N)n1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N11 compound treatment 1248346.0 370000.0 0.78 1339930.0 408000.0 0.93 1.2098 0.9966 1455493 Maybridge3_001353 CNc1ccc(Cl)cc1C(=O)NCCc2ccc(OC)c(OC)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N12 compound treatment 1384676.0 506000.0 1.07 1392585.0 460000.0 1.05 1.4988 0.9999 1082548 Maybridge3_001354 Clc1ccc(cc1)c2cc(=S)ss2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N13 compound treatment 1321423.0 443000.0 0.94 1294513.0 362000.0 0.82 1.2463 0.9978 1452031 Maybridge3_001355 Cc1c(C)c(C)c(CCN)c(C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N14 compound treatment 1154343.0 276000.0 0.59 1192506.0 260000.0 0.59 0.8319 1.0 2075915 Maybridge3_001356 O=C(CC(C(C#N)C#N)c1ccccc1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N15 compound treatment 1037113.0 159000.0 0.34 1298320.0 366000.0 0.83 0.8262 0.9207 1536665 Maybridge3_001357 O=C(NCc1cccnc1)c2nc3ccccc3c(=O)[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N16 compound treatment 1138756.0 260000.0 0.55 1310957.0 379000.0 0.86 0.9989 0.9769 2075916 Maybridge3_001358 FC(F)(F)c1cc(cc(c1)C(F)(F)F)N2C(=O)CCC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N17 compound treatment 1230273.0 352000.0 0.75 1344305.0 412000.0 0.94 1.1897 0.9937 2075917 Maybridge3_001359 COc1ccc(C/N=C/c2cc(Cl)cc(Cl)c2O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N18 compound treatment 1197376.0 319000.0 0.68 1385664.0 453000.0 1.03 1.2069 0.9791 2075918 Maybridge3_001360 CSc1nc2ccnn2c(=O)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N19 compound treatment 1286259.0 408000.0 0.86 1575676.0 643000.0 1.46 1.6456 0.9686 2075919 Maybridge3_001361 COC(=O)CSc1nnc([nH]1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N20 compound treatment 1170654.0 292000.0 0.62 1556174.0 624000.0 1.42 1.441 0.9311 1716607 Maybridge3_001362 Cn1cc(Br)c(NC(=O)c2ccc(Cl)c(Cl)c2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N21 compound treatment 1255156.0 377000.0 0.8 1405760.0 473000.0 1.08 1.3258 0.9892 1729999 Maybridge3_001363 CCOC(=O)c1sc2ccc(NC(=O)C)cc2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N22 compound treatment 1191876.0 314000.0 0.66 1353178.0 421000.0 0.96 1.1464 0.9842 2075920 Maybridge3_001364 NC(=O)c1sccc1NC(=O)CSc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N23 mock treatment 1151216.0 273000.0 0.58 1166788.0 234000.0 0.53 0.7858 0.9992 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 N24 mock treatment 609957.0 -268000.0 -0.57 859211.0 -73200.0 -0.17 -0.52 -0.8771 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O01 compound treatment 590876.0 -287000.0 -0.61 763786.0 -169000.0 -0.38 -0.702 -0.975 2075921 Maybridge3_001365 Cc1nn(C)c(O)c1C(=O)c2c(C)onc2c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O02 compound treatment 1108094.0 230000.0 0.49 1230983.0 299000.0 0.68 0.8244 0.9867 2075922 Maybridge3_001366 O/N=C/NC(=O)C1CCN(CC1)c2cccc(Cl)c2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O03 compound treatment 1140332.0 262000.0 0.56 1164516.0 232000.0 0.53 0.7659 0.9997 2075923 Maybridge3_001367 Cc1n[nH]c(C)c1Cc2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O04 compound treatment 1298374.0 420000.0 0.89 1239013.0 307000.0 0.7 1.1225 0.9927 1218923 Maybridge3_001368 O=C(NC1CCSC1)c2ccccc2NS(=O)(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O05 compound treatment 1039389.0 161000.0 0.34 1020901.0 88500.0 0.2 0.3837 0.9682 2075924 Maybridge3_001369 NC(=N)SCc1cccc(CSC(=N)N)c1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O06 compound treatment 1249705.0 371000.0 0.79 1327488.0 395000.0 0.9 1.1918 0.9978 2075925 Maybridge3_001370 Clc1ccc(NC(=O)OC2CCSC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O07 compound treatment 1302108.0 424000.0 0.9 1082345.0 150000.0 0.34 0.8763 0.912 2075926 Maybridge3_001371 Nc1oc(c(C#N)c1c2ccc(C#N)cc2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O08 compound treatment 1339607.0 461000.0 0.98 1177904.0 246000.0 0.56 1.0861 0.9647 1326203 Maybridge3_001372 NC(=O)c1ccc(cc1)S(=O)(=O)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O09 compound treatment 1355353.0 477000.0 1.01 1300850.0 368000.0 0.84 1.3074 0.9956 1344241 Maybridge3_001373 CN(C)c1cccc(N(C)C)c1CNC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O10 compound treatment 1291686.0 413000.0 0.88 1339576.0 407000.0 0.93 1.2742 0.9996 2075927 Maybridge3_001374 CS(=O)(=O)n1nccc1c2ccc(o2)c3ccc(F)cc3F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O11 compound treatment 1420095.0 542000.0 1.15 1266289.0 334000.0 0.76 1.3489 0.9798 2075928 Maybridge3_001375 O=C(Oc1cccc(c1)N2CCOCC2)c3ccc(CSC(=S)N4CCSCC4)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O12 compound treatment 1445945.0 568000.0 1.2 1404396.0 472000.0 1.07 1.6096 0.9984 2075929 Maybridge3_001376 COC(=O)Nc1cc(OC)cc(c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O13 compound treatment 1358681.0 480000.0 1.02 1277574.0 345000.0 0.78 1.2749 0.9917 1218908 Maybridge3_001377 CN(C)c1cccc(N(C)C)c1CNC(=O)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O14 compound treatment 1337371.0 459000.0 0.97 1063175.0 131000.0 0.3 0.8983 0.8829 1303697 Maybridge3_001378 CS(=O)(=O)CC(=O)NC1CCCCC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O15 compound treatment 1387329.0 509000.0 1.08 1182788.0 250000.0 0.57 1.1655 0.9554 2075930 Maybridge3_001379 Cc1n[nH]cc1c2ccccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O16 compound treatment 1301184.0 423000.0 0.9 1101894.0 170000.0 0.39 0.9063 0.9289 2075931 Maybridge3_001380 Clc1cc(CSC(=S)NCc2cccnc2)c(Cl)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O17 compound treatment 1139297.0 261000.0 0.55 1131975.0 200000.0 0.45 0.712 0.9952 2075932 Maybridge3_001381 CS/C(=N/C#N)/NCc1c(cccc1N(C)C)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O18 compound treatment 1264242.0 386000.0 0.82 1164118.0 232000.0 0.53 0.951 0.9774 2075933 Maybridge3_001382 COc1ccc(Oc2cccc(Cl)c2C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O19 compound treatment 1493623.0 615000.0 1.3 1120592.0 188000.0 0.43 1.2249 0.8923 2075934 Maybridge3_001383 CS/C(=N\C#N)/Nc1c(C)nn(C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O20 compound treatment 1694818.0 816000.0 1.73 1180888.0 249000.0 0.56 1.6234 0.8916 2075935 Maybridge3_001384 Fc1cccc(N2CCC(CC2)C#N)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O21 compound treatment 1523103.0 645000.0 1.37 1335193.0 403000.0 0.92 1.614 0.981 2075936 Maybridge3_001385 CC1=C(OC(=O)c2c(C)onc2c3c(Cl)cccc3Cl)C(=O)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O22 compound treatment 1500126.0 622000.0 1.32 1297097.0 365000.0 0.83 1.5184 0.975 2075937 Maybridge3_001386 O=S(=O)(c1ccccc1)c2ccc(cc2)c3ccn[nH]3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O23 mock treatment 1293473.0 415000.0 0.88 1038050.0 106000.0 0.24 0.7921 0.8684 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 O24 mock treatment 699007.0 -179000.0 -0.38 786997.0 -145000.0 -0.33 -0.5026 -0.9976 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P01 compound treatment 478149.0 -400000.0 -0.85 492673.0 -440000.0 -1.0 -1.3068 -0.9967 2075938 Maybridge3_001387 CC1N(CCc2sccc12)C(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P02 compound treatment 530827.0 -348000.0 -0.74 646697.0 -286000.0 -0.65 -0.9803 -0.998 2075939 Maybridge3_001388 COc1ccccc1/N=C/2\NC3(CCCCC3)C(=C)S2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P03 compound treatment 727549.0 -151000.0 -0.32 821881.0 -111000.0 -0.25 -0.4037 -0.9929 1378845 Maybridge3_001389 O=S(=O)(Nc1ccc(cc1)c2cnco2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P04 compound treatment 799504.0 -78900.0 -0.17 866718.0 -65700.0 -0.15 -0.2238 -0.9984 1403222 Maybridge3_001390 CC1CN(CCC(=O)Nc2ccc(Cl)cc2C(=O)c3ccccc3)CC(C)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P05 compound treatment 880823.0 2450.0 0.01 856132.0 -76300.0 -0.17 -0.1189 -0.6856 1714399 Maybridge3_001391 NC(=O)c1c(N)c(sc1Nc2ccccc2)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P06 compound treatment 967396.0 89000.0 0.19 901876.0 -30500.0 -0.07 0.0844 0.4198 2075940 Maybridge3_001392 Fc1ccc(cc1)S(=O)(=O)Nc2ccc(F)c(F)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P07 compound treatment 959315.0 80900.0 0.17 886564.0 -45800.0 -0.1 0.0477 0.2375 1234015 Maybridge3_001393 O=C(Nc1nncs1)c2ccccc2NC(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P08 compound treatment 865284.0 -13100.0 -0.03 803757.0 -129000.0 -0.29 -0.2264 -0.7708 2075941 Maybridge3_001394 CN(C)CC1=C(Cl)c2ccccc2S1(=O)=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P09 compound treatment 953033.0 74700.0 0.16 832374.0 -100000.0 -0.23 -0.0489 -0.1764 2075942 Maybridge3_001395 O=C/1/C(=C/c2cccs2)/CC\C1=C/c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P10 compound treatment 960595.0 82200.0 0.17 885674.0 -46700.0 -0.11 0.0482 0.236 2075943 Maybridge3_001396 CSc1cc(nc(n1)c2ccc(Cl)cc2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P11 compound treatment 945691.0 67300.0 0.14 829712.0 -103000.0 -0.23 -0.0641 -0.2345 2075944 Maybridge3_001397 Cc1ccc(CSC2=NCCCN2)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P12 compound treatment 971059.0 92700.0 0.2 925766.0 -6620.0 -0.02 0.1283 0.6511 2075945 Maybridge3_001398 O=C1/C(=C/c2ccc[nH]2)/Cc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P13 compound treatment 939423.0 61000.0 0.13 863474.0 -68900.0 -0.16 -0.0193 -0.0948 2075946 Maybridge3_001399 N#CSCc1ccc(C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P14 compound treatment 1035955.0 158000.0 0.33 1010208.0 77800.0 0.18 0.3613 0.9558 2075947 Maybridge3_001400 Nc1nccc(n1)c2ccc3OCCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P15 compound treatment 1203566.0 325000.0 0.69 1021456.0 89100.0 0.2 0.6307 0.8777 1180190 Maybridge3_001401 Oc1nc(nc2ccccc12)C(=O)NCCc3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P16 compound treatment 1138031.0 260000.0 0.55 1002696.0 70300.0 0.16 0.5023 0.8763 1461261 Maybridge3_001402 CC(=O)Nc1ccsc1C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P17 compound treatment 1004453.0 126000.0 0.27 929997.0 -2390.0 -0.01 0.1852 0.6926 1713486 Maybridge3_001403 Clc1ccc(OCc2nc3ccccc3c(=O)o2)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P18 compound treatment 1112356.0 234000.0 0.5 954244.0 21900.0 0.05 0.3859 0.7741 1984555 Maybridge3_001404 CCc1cc2c(=O)[nH]cnc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P19 compound treatment 1370671.0 492000.0 1.04 1127599.0 195000.0 0.44 1.0518 0.9274 2075948 Maybridge3_001405 FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)N2CCC=CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P20 compound treatment 1292252.0 414000.0 0.88 1227415.0 295000.0 0.67 1.0947 0.9912 1533743 Maybridge3_001406 Clc1ccc(s1)S(=O)(=O)Nc2[nH]ncc2Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P21 compound treatment 1252610.0 374000.0 0.79 1039240.0 107000.0 0.24 0.7328 0.8832 1290814 Maybridge3_001407 Oc1ccc(cc1)C(=O)CCN2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P22 compound treatment 954215.0 75800.0 0.16 1077319.0 145000.0 0.33 0.3467 0.9456 2075949 Maybridge3_001408 NC(=O)c1sccc1NC(=O)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P23 mock treatment 677308.0 -201000.0 -0.43 746319.0 -186000.0 -0.42 -0.6005 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1434 P24 mock treatment 576828.0 -302000.0 -0.64 520658.0 -412000.0 -0.94 -1.1139 -0.9827 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A01 compound treatment 450228.0 -347000.0 -0.73 387243.0 -293000.0 -0.67 -0.9905 -0.9988 2076514 Maybridge3_002817 CC1CC(=O)Nc2ccccc2N1C(=O)c3cc(Cl)sc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A02 compound treatment 496589.0 -300000.0 -0.64 405028.0 -275000.0 -0.63 -0.8925 -1.0 2076515 Maybridge3_002818 COc1ccc(NCc2ccc[nH]2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A03 compound treatment 483000.0 -314000.0 -0.67 415117.0 -265000.0 -0.6 -0.8966 -0.9988 2076516 Maybridge3_002819 FC(F)(F)c1ccc(cc1)c2nnc(o2)c3ccc4nccnc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A04 compound treatment 520981.0 -276000.0 -0.58 587847.0 -92300.0 -0.21 -0.562 -0.9043 2076517 Maybridge3_002820 CC(C)(C)c1ccc(NC(=O)c2ccsc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A05 compound treatment 553802.0 -243000.0 -0.52 577975.0 -102000.0 -0.23 -0.5287 -0.9352 1249645 Maybridge3_002821 CCC1c2c(Oc3c1c(=O)oc4ccccc34)nc(C)[nH]c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A06 compound treatment 583498.0 -213000.0 -0.45 497705.0 -182000.0 -0.41 -0.6132 -0.9991 1289349 Maybridge3_002822 Clc1cc(c(Cl)s1)S(=O)(=O)NCC2COc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A07 compound treatment 543617.0 -253000.0 -0.54 439585.0 -241000.0 -0.55 -0.7664 -1.0 2076518 Maybridge3_002823 O=C1N(Cc2ccc3nsnc3c2)S(=O)(=O)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A08 compound treatment 550655.0 -246000.0 -0.52 567667.0 -112000.0 -0.26 -0.5499 -0.9461 2076519 Maybridge3_002824 COc1ccc(cc1)c2nnsc2NC(=O)c3ccccc3CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A09 compound treatment 645811.0 -151000.0 -0.32 704295.0 24200.0 0.05 -0.1877 -0.5774 2076520 Maybridge3_002825 COc1ccccc1CC(=O)NC(=O)c2ccccc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A10 compound treatment 607661.0 -189000.0 -0.4 686274.0 6150.0 0.01 -0.2738 -0.6821 2076521 Maybridge3_002826 OC(=O)COCc1ccc(Br)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A11 compound treatment 557335.0 -240000.0 -0.51 580412.0 -99700.0 -0.23 -0.5194 -0.9339 1113215 Maybridge3_002827 O=C1Nc2ccccc2C1Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A12 compound treatment 515384.0 -282000.0 -0.6 554266.0 -126000.0 -0.29 -0.6244 -0.9433 1054438 Maybridge3_002828 OC(=O)c1cccc(CC=C)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A13 compound treatment 560940.0 -236000.0 -0.5 516684.0 -163000.0 -0.37 -0.6165 -0.9893 2076522 Maybridge3_002829 COc1cccc(c1)C(=O)Nc2n[nH]c(SCc3ccc(Cl)cc3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A14 compound treatment 636574.0 -160000.0 -0.34 653611.0 -26500.0 -0.06 -0.283 -0.8197 2076523 Maybridge3_002830 CCOC(=O)c1nnc(o1)c2ccc(cc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A15 compound treatment 644339.0 -153000.0 -0.32 585010.0 -95100.0 -0.22 -0.3816 -0.9808 2076524 Maybridge3_002831 Cn1nc(cc1NC(=O)C2CCCCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A16 compound treatment 541222.0 -256000.0 -0.54 554416.0 -126000.0 -0.29 -0.5854 -0.9553 2076525 Maybridge3_002832 CCCSc1ncccc1C(=O)Nc2cccc3nonc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A17 compound treatment 573885.0 -223000.0 -0.47 548006.0 -132000.0 -0.3 -0.5467 -0.976 2076526 Maybridge3_002833 O=c1[nH]c(cc(c2ccco2)c1C#N)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A18 compound treatment 497826.0 -299000.0 -0.63 494926.0 -185000.0 -0.42 -0.7461 -0.9802 2076527 Maybridge3_002834 Clc1ccc(cc1)C2=NOC(C2)C(=O)NCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A19 compound treatment 618189.0 -179000.0 -0.38 571367.0 -109000.0 -0.25 -0.4428 -0.9786 2076528 Maybridge3_002835 OC(=O)CCc1ccc2OCCc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A20 compound treatment 542079.0 -255000.0 -0.54 501542.0 -179000.0 -0.41 -0.6691 -0.9901 2076529 Maybridge3_002836 C=CCSc1nnc2NCCCn12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A21 compound treatment 517603.0 -279000.0 -0.59 487073.0 -193000.0 -0.44 -0.7291 -0.9891 2076530 Maybridge3_002837 Oc1ccccc1C(=O)NC(=O)c2ccc(F)cc2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A22 compound treatment 464747.0 -332000.0 -0.7 444566.0 -236000.0 -0.54 -0.8766 -0.9909 2076531 Maybridge3_002838 C/C(=C\1/CCOC1=O)/Nc2ccccc2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A23 mock treatment 474199.0 -323000.0 -0.68 433463.0 -247000.0 -0.56 -0.8803 -0.9951 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 A24 mock treatment 415034.0 -382000.0 -0.81 374890.0 -305000.0 -0.69 -1.0632 -0.9971 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B01 compound treatment 495835.0 -301000.0 -0.64 369244.0 -311000.0 -0.71 -0.9511 -0.9987 2076532 Maybridge3_002839 CSc1ncnc2n(Cc3ccccc3)nnc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B02 compound treatment 670533.0 -126000.0 -0.27 805694.0 126000.0 0.29 0.0124 0.0317 1077132 Maybridge3_002840 COc1ccc2c(OC)cccc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B03 compound treatment 798026.0 1110.0 0.0 839202.0 159000.0 0.36 0.2574 0.7117 2076533 Maybridge3_002841 Clc1ccc(COc2ccncc2)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B04 compound treatment 928493.0 132000.0 0.28 997783.0 318000.0 0.72 0.7079 0.9144 1396844 Maybridge3_002842 CCS(=O)CC(=O)Nc1c(oc2ccccc2c1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B05 compound treatment 900050.0 103000.0 0.22 1143706.0 464000.0 1.05 0.8999 0.836 2076534 Maybridge3_002843 CSc1nnc(c2sc3nc(C)cc(C)c3c2N)n1Cc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B06 compound treatment 939278.0 142000.0 0.3 1154286.0 474000.0 1.08 0.9757 0.8716 2076535 Maybridge3_002844 Fc1ccc(cc1)C(=O)/C=C/OC(=O)c2ccc(cc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B07 compound treatment 882565.0 85700.0 0.18 1062020.0 382000.0 0.87 0.7423 0.8369 2076536 Maybridge3_002845 Nc1nc(ncc1C#N)N2CCc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B08 compound treatment 918835.0 122000.0 0.26 1065856.0 386000.0 0.88 0.8029 0.8782 2076537 Maybridge3_002846 CN(C)c1ccc(/C=C/c2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B09 compound treatment 948717.0 152000.0 0.32 1054189.0 374000.0 0.85 0.8289 0.9116 2076538 Maybridge3_002847 CCOC(=O)CSc1nc(NC)c2c3CCCCc3sc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B10 compound treatment 201134.0 -596000.0 -1.26 199198.0 -481000.0 -1.09 -1.6663 -0.9974 2076539 Maybridge3_002848 CC(=O)Oc1c(sc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B11 compound treatment 1147445.0 351000.0 0.74 1066700.0 387000.0 0.88 1.1469 0.9965 2076540 Maybridge3_002849 COc1cccc(Nc2ncc(C#N)c(N)n2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B12 compound treatment 1115281.0 318000.0 0.67 1188818.0 509000.0 1.16 1.295 0.9671 2076541 Maybridge3_002850 CC1(C)OC2OC(CO)C(O)C(O)C2O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B13 compound treatment 1142429.0 346000.0 0.73 1204233.0 524000.0 1.19 1.3605 0.9727 2076542 Maybridge3_002851 Nc1ncc(cc1C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B14 compound treatment 1020378.0 223000.0 0.47 1148542.0 468000.0 1.06 1.088 0.9335 2076543 Maybridge3_002852 CCSC(=O)NCc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B15 compound treatment 1161144.0 364000.0 0.77 1128474.0 448000.0 1.02 1.2668 0.9906 2076544 Maybridge3_002853 CCOC(=O)Cn1sc2nc(C)cc(C)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B16 compound treatment 1059353.0 262000.0 0.56 1087087.0 407000.0 0.93 1.0476 0.9704 1548418 Maybridge3_002854 Fc1ccccc1CC(=O)NCCc2c[nH]c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B17 compound treatment 1067168.0 270000.0 0.57 1132023.0 452000.0 1.03 1.1316 0.962 2076545 Maybridge3_002855 Cc1ccccc1n2cc(nc2SCC(=O)N)c3ccc(Br)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B18 compound treatment 1067662.0 271000.0 0.57 1112230.0 432000.0 0.98 1.1005 0.9672 1022389 Maybridge3_002856 CN(C)c1ccc(cc1)C(=S)c2ccc(cc2)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B19 compound treatment 1165757.0 369000.0 0.78 1188767.0 509000.0 1.16 1.3706 0.9818 2076546 Maybridge3_002857 Cc1cc(C)c2c(N)c(sc2n1)C(=O)Nc3nnc(s3)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B20 compound treatment 1119958.0 323000.0 0.68 947970.0 268000.0 0.61 0.9148 0.9983 1291803 Maybridge3_002858 CC(CN1CCN(Cc2ccccc2)CC1)N(C(=O)c3ccoc3)c4ccccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B21 compound treatment 1085038.0 288000.0 0.61 1075247.0 395000.0 0.9 1.0671 0.9823 2076547 Maybridge3_002859 Nc1nc(cc(c2cccs2)c1C#N)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B22 compound treatment 1084051.0 287000.0 0.61 954655.0 275000.0 0.62 0.8718 0.9999 1707826 Maybridge3_002860 OCC(CO)NC(=O)OCC1c2ccccc2-c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B23 mock treatment 896449.0 99500.0 0.21 742669.0 62500.0 0.14 0.2497 0.9815 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 B24 mock treatment 515595.0 -281000.0 -0.6 462088.0 -218000.0 -0.5 -0.7722 -0.9958 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C01 compound treatment 512668.0 -284000.0 -0.6 481947.0 -198000.0 -0.45 -0.7447 -0.9897 2076548 Maybridge3_002861 Cc1nnsc1C(=O)NCc2ccc(cc2)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C02 compound treatment 685468.0 -111000.0 -0.24 730441.0 50300.0 0.11 -0.0862 -0.3283 2076549 Maybridge3_002862 COc1ccc(cc1)N(Cc2ccccn2)C(=O)c3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C03 compound treatment 853743.0 56800.0 0.12 964937.0 285000.0 0.65 0.5431 0.8245 2076550 Maybridge3_002863 CCOC(=O)c1cnn(C(=O)c2cccc3ccccc23)c1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C04 compound treatment 966282.0 169000.0 0.36 1048637.0 369000.0 0.84 0.8463 0.9285 2076551 Maybridge3_002864 O=C(NCc1ccco1)c2ccsc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C05 compound treatment 946466.0 150000.0 0.32 1172875.0 493000.0 1.12 1.0163 0.8729 2076552 Maybridge3_002865 C=CCn1c(=S)sc2c(ncnc12)N3CCN(CC3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C06 compound treatment 1016024.0 219000.0 0.46 1443948.0 764000.0 1.74 1.5564 0.8658 1509965 Maybridge3_002866 O=S(=O)(NCC1COc2ccccc2O1)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C07 compound treatment 902362.0 105000.0 0.22 1287716.0 608000.0 1.38 1.1349 0.811 2076553 Maybridge3_002867 Cc1cc(CN2C(=O)c3ccccc3S2(=O)=O)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C08 compound treatment 1061547.0 265000.0 0.56 1353975.0 674000.0 1.53 1.48 0.9071 2076554 Maybridge3_002868 CCOC(=O)c1cn2nc(Oc3ccccc3)ccc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C09 compound treatment 955803.0 159000.0 0.34 1202026.0 522000.0 1.19 1.0772 0.8733 2076555 Maybridge3_002869 Oc1ccccc1C(=O)NC(=O)c2sc3ccccc3c2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C10 compound treatment 910454.0 114000.0 0.24 1160963.0 481000.0 1.09 0.9432 0.8426 2076556 Maybridge3_002870 CC(C)(C)OC(=O)N1CCCN(CC1)S(=O)(=O)c2cccc(c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C11 compound treatment 985603.0 189000.0 0.4 1239514.0 559000.0 1.27 1.1821 0.8867 2076557 Maybridge3_002871 c1snnc1c2ccc(cc2)c3nc(cs3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C12 compound treatment 1162135.0 365000.0 0.77 1397801.0 718000.0 1.63 1.7012 0.942 2076558 Maybridge3_002872 Clc1ccc(cc1)n2ncc(n2)C(=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C13 compound treatment 1043622.0 247000.0 0.52 1453542.0 773000.0 1.76 1.6132 0.8794 1294098 Maybridge3_002873 Cc1onc(c1C(=O)N2CCCc3ccccc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C14 compound treatment 1085645.0 289000.0 0.61 1438152.0 758000.0 1.72 1.6514 0.903 2076559 Maybridge3_002874 N(c1nnc(o1)c2cccc3ccccc23)c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C15 compound treatment 998300.0 201000.0 0.43 1058255.0 378000.0 0.86 0.9098 0.9478 2076560 Maybridge3_002875 Cn1nc(cc1NC(=O)CCCC(=O)O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C16 compound treatment 1071661.0 275000.0 0.58 1251003.0 571000.0 1.3 1.3296 0.9346 2076561 Maybridge3_002876 CCCSc1ncccc1C(=O)Nc2cc(C)no2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C17 compound treatment 900336.0 103000.0 0.22 1161960.0 482000.0 1.1 0.9296 0.8321 1213370 Maybridge3_002877 O=c1[nH]c(cc(c2ccco2)c1C#N)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C18 compound treatment 1110710.0 314000.0 0.67 1140489.0 460000.0 1.05 1.2105 0.9761 2076562 Maybridge3_002878 O=C(OCC1CC(=NO1)c2ccccc2)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C19 compound treatment 1076989.0 280000.0 0.59 1230942.0 551000.0 1.25 1.3054 0.9419 2076563 Maybridge3_002879 C/C(=N\O)/C(C)(C)NCCc1c[nH]c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C20 compound treatment 1120253.0 323000.0 0.69 1189273.0 509000.0 1.16 1.3032 0.9687 2076564 Maybridge3_002880 CCOC(=O)CSc1nnc(c2ccncc2)n1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C21 compound treatment 1030120.0 233000.0 0.49 1185529.0 505000.0 1.15 1.1621 0.929 2076565 Maybridge3_002881 CCC1(CCCCNC1=O)c2cccc(OC)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C22 compound treatment 994003.0 197000.0 0.42 1246479.0 566000.0 1.29 1.2059 0.8908 2076566 Maybridge3_002882 C/C(=C\1/CCOC1=O)/Nc2ccccc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C23 mock treatment 957540.0 161000.0 0.34 922776.0 243000.0 0.55 0.6309 0.9731 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 C24 mock treatment 486900.0 -310000.0 -0.66 443607.0 -237000.0 -0.54 -0.845 -0.995 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D01 compound treatment 467575.0 -329000.0 -0.7 404012.0 -276000.0 -0.63 -0.9376 -0.9986 2076567 Maybridge3_002883 S=c1[nH]cnc2n(Cc3ccccc3)nnc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D02 compound treatment 670811.0 -126000.0 -0.27 756241.0 76100.0 0.17 -0.0667 -0.2094 2076568 Maybridge3_002884 O=C(NC1CCCCC1)SCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D03 compound treatment 714227.0 -82700.0 -0.18 773538.0 93400.0 0.21 0.0262 0.0952 2076569 Maybridge3_002885 CC(C)(C)OC(=O)N1C(COC1(C)C)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D04 compound treatment 959166.0 162000.0 0.34 974393.0 294000.0 0.67 0.7163 0.9522 1721183 Maybridge3_002886 Clc1ccc2C(=O)CC(Oc2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D05 compound treatment 876322.0 79400.0 0.17 1019812.0 340000.0 0.77 0.6651 0.8415 2076570 Maybridge3_002887 CCOC(=O)c1nnn2c1nc(SCC=C)c3ccccc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D06 compound treatment 1056082.0 259000.0 0.55 1124581.0 444000.0 1.01 1.103 0.959 1280047 Maybridge3_002888 CC1(C)Oc2cc(OCC(=O)Nc3ccccc3)ccc2C=C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D07 compound treatment 984270.0 187000.0 0.4 1072338.0 392000.0 0.89 0.9114 0.9336 2076571 Maybridge3_002889 C=CCC(C(=O)N1CCc2ccccc12)C(=O)N3CCc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D08 compound treatment 1167792.0 371000.0 0.79 1054385.0 374000.0 0.85 1.1576 0.9992 2076572 Maybridge3_002890 CC(C)(C)C(Cc1ccccc1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D09 compound treatment 1190684.0 394000.0 0.83 1065857.0 386000.0 0.88 1.2104 0.9997 2076573 Maybridge3_002891 Nc1c(cnn1c2ccccc2)c3nnc(SCc4ccc(Cl)cc4)o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D10 compound treatment 988209.0 191000.0 0.41 1310458.0 630000.0 1.43 1.3001 0.8729 2076574 Maybridge3_002892 COC(=O)c1ccccc1S(=O)(=O)Cc2ccc(OC)c(OC)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D11 compound treatment 925193.0 128000.0 0.27 1173949.0 494000.0 1.12 0.9862 0.8537 2076575 Maybridge3_002893 C=CCn1c2ccccc2c3nn4cnnc4nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D12 compound treatment 1200804.0 404000.0 0.86 1480563.0 800000.0 1.82 1.8923 0.9409 2076576 Maybridge3_002894 O=C(OCC#N)c1ccc(cc1)c2cc(=O)c3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D13 compound treatment 1109030.0 312000.0 0.66 1546049.0 866000.0 1.97 1.86 0.8955 2076577 Maybridge3_002895 CCOC(=O)N1CCc2c(C1)sc3nc[nH]c(=O)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D14 compound treatment 1131999.0 335000.0 0.71 1301069.0 621000.0 1.41 1.5006 0.9495 2076578 Maybridge3_002896 O=C(NC1CCCCC1)Sc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D15 compound treatment 1089700.0 293000.0 0.62 1140615.0 460000.0 1.05 1.1792 0.9689 2076579 Maybridge3_002897 Cc1cc(C)c2c(=O)n(sc2n1)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D16 compound treatment 981854.0 185000.0 0.39 1301833.0 622000.0 1.41 1.2767 0.8704 2076580 Maybridge3_002898 O=C(Oc1ccc(Oc2ccccc2)cc1)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D17 compound treatment 963545.0 167000.0 0.35 1305833.0 626000.0 1.42 1.2557 0.8567 2076581 Maybridge3_002899 O=C(CSc1ncnc2sc(cc12)c3ccccc3)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D18 compound treatment 1256552.0 460000.0 0.97 1423441.0 743000.0 1.69 1.884 0.9658 1261683 Maybridge3_002900 COc1ccc(cc1)C(O)(C2CC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D19 compound treatment 1160064.0 363000.0 0.77 1370180.0 690000.0 1.57 1.6537 0.9463 2076582 Maybridge3_002901 OC(=O)CSc1nnc([nH]1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D20 compound treatment 1073229.0 276000.0 0.59 1370445.0 690000.0 1.57 1.524 0.9097 1490238 Maybridge3_002902 Cc1ccc(Sc2ccccc2C(=O)O)c(c1)S(=O)(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D21 compound treatment 1166576.0 370000.0 0.78 1255119.0 575000.0 1.31 1.4785 0.97 2076583 Maybridge3_002903 COc1ccc(cc1)c2cc(c3ccccc3)c4c(N)ncnc4n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D22 compound treatment 1039315.0 242000.0 0.51 1283404.0 603000.0 1.37 1.3332 0.9102 2076584 Maybridge3_002904 CC(=O)OC1CSSCC1OC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D23 mock treatment 1011619.0 215000.0 0.46 1036266.0 356000.0 0.81 0.8944 0.9629 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 D24 mock treatment 559020.0 -238000.0 -0.5 485185.0 -195000.0 -0.44 -0.67 -0.9979 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E01 compound treatment 617696.0 -179000.0 -0.38 608861.0 -71300.0 -0.16 -0.3832 -0.9278 2076585 Maybridge3_002905 FC(F)(F)c1ccc(cc1)S(=O)(=O)NCc2ccc(cc2)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E02 compound treatment 972103.0 175000.0 0.37 1074502.0 394000.0 0.9 0.8966 0.9239 2076586 Maybridge3_002906 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E03 compound treatment 1035887.0 239000.0 0.51 946716.0 267000.0 0.61 0.7868 0.996 1731255 Maybridge3_002907 Cc1cc(on1)c2ccccc2C(=O)NC3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E04 compound treatment 1133141.0 336000.0 0.71 1079046.0 399000.0 0.91 1.1453 0.9929 2076587 Maybridge3_002908 Clc1ccc(CSc2nc(NS(=O)(=O)c3ccccc3)n[nH]2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E05 compound treatment 1131445.0 335000.0 0.71 1038410.0 358000.0 0.81 1.0775 0.9976 1589685 Maybridge3_002909 CN1CCN(CC1)c2nc(C)nc3n(c4ccccc4)c(=S)sc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E06 compound treatment 1272648.0 476000.0 1.01 1183721.0 504000.0 1.14 1.5227 0.998 2076588 Maybridge3_002910 COc1ccc(NS(=O)(=O)c2ccc(Cl)s2)cn1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E07 compound treatment 1164017.0 367000.0 0.78 1071651.0 392000.0 0.89 1.1797 0.9978 2076589 Maybridge3_002911 Cc1ccc(cc1)C(=O)CN2C(=O)c3ccccc3S2(=O)=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E08 compound treatment 1116396.0 319000.0 0.68 1292455.0 612000.0 1.39 1.4633 0.9452 2076590 Maybridge3_002912 Clc1ccc(cc1)c2nc3ccccc3[nH]c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E09 compound treatment 1234939.0 438000.0 0.93 1095647.0 416000.0 0.94 1.3246 1.0 2076591 Maybridge3_002913 Cc1ccc(Oc2ncccc2C(=O)NC(=O)c3ccccc3O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E10 compound treatment 1188900.0 392000.0 0.83 1206358.0 526000.0 1.2 1.4336 0.9841 2076592 Maybridge3_002914 COc1cccc(Cc2nnc(o2)c3ccc4OCOc4c3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E11 compound treatment 1437157.0 640000.0 1.36 1008387.0 328000.0 0.75 1.4875 0.9603 2076593 Maybridge3_002915 CS(=O)(=O)c1ccc(cc1)c2csc(n2)c3ccc(cc3)c4csnn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E12 compound treatment 1224892.0 428000.0 0.91 1542481.0 862000.0 1.96 2.0279 0.9387 2076594 Maybridge3_002916 Nc1nn(nc1C(=O)c2ccccc2)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E13 compound treatment 1181813.0 385000.0 0.82 1136684.0 457000.0 1.04 1.311 0.9929 2076595 Maybridge3_002917 Cc1nc(sc1C(=O)N2CCCc3ccccc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E14 compound treatment 1260453.0 464000.0 0.98 1235179.0 555000.0 1.26 1.5872 0.9924 2076596 Maybridge3_002918 C/C(=N\O)/C(C)(C)Nc1ccc2OCOc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E15 compound treatment 1223741.0 427000.0 0.9 1166982.0 487000.0 1.11 1.4225 0.995 2076597 Maybridge3_002919 Cn1nc(cc1NC(=O)c2ccccc2C(=O)O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E16 compound treatment 1065440.0 269000.0 0.57 1187298.0 507000.0 1.15 1.2179 0.9471 2076598 Maybridge3_002920 FC(F)(F)c1ccc(NS(=O)(=O)c2ccccc2)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E17 compound treatment 1109131.0 312000.0 0.66 1267178.0 587000.0 1.33 1.4118 0.9476 1509251 Maybridge3_002921 O=c1[nH]c(cc(c2ccco2)c1C#N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E18 compound treatment 1148587.0 352000.0 0.75 1204919.0 525000.0 1.19 1.3708 0.9744 2076599 Maybridge3_002922 O(c1ccccn1)c2cccc3cccnc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E19 compound treatment 1292255.0 495000.0 1.05 1079275.0 399000.0 0.91 1.3842 0.9974 2076600 Maybridge3_002923 C/C(=N\O)/C(C)(C)Nc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E20 compound treatment 1281263.0 484000.0 1.03 1075346.0 395000.0 0.9 1.3614 0.9978 2076601 Maybridge3_002924 CC1CCc2c(C#N)c(NC(=O)CSc3nccn3C)sc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E21 compound treatment 1260418.0 464000.0 0.98 1049044.0 369000.0 0.84 1.2879 0.9969 2076602 Maybridge3_002925 Cc1ccc(cc1)c2nc(=O)c3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E22 compound treatment 1120167.0 323000.0 0.69 1147837.0 468000.0 1.06 1.2365 0.9774 2076603 Maybridge3_002926 C/C(=C\1/CCOC1=O)/Nc2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E23 mock treatment 966406.0 169000.0 0.36 979756.0 300000.0 0.68 0.7358 0.9553 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 E24 mock treatment 625052.0 -172000.0 -0.36 482505.0 -198000.0 -0.45 -0.5753 -0.9946 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F01 compound treatment 490805.0 -306000.0 -0.65 617181.0 -62900.0 -0.14 -0.5601 -0.8428 2076604 Maybridge3_002927 FC(F)(F)c1cccc(Nc2ncnc3n(Cc4ccccc4)nnc23)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F02 compound treatment 812749.0 15800.0 0.03 882397.0 202000.0 0.46 0.3489 0.7567 2076605 Maybridge3_002928 CC(C)(C)NC(=O)Oc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F03 compound treatment 806735.0 9820.0 0.02 907863.0 228000.0 0.52 0.3808 0.7349 2076606 Maybridge3_002929 CC(C)CC(NC(=O)c1ccc(Cl)cc1Cl)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F04 compound treatment 1170925.0 374000.0 0.79 1053377.0 373000.0 0.85 1.1607 0.9994 2076607 Maybridge3_002930 OC1C(Oc2ccccc2C1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F05 compound treatment 1030340.0 233000.0 0.49 1039041.0 359000.0 0.82 0.9269 0.9713 2076608 Maybridge3_002931 Clc1ccc(cc1)n2c(Cn3nnc4ccccc34)nnc2SCC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F06 compound treatment 1110516.0 314000.0 0.66 1157269.0 477000.0 1.08 1.2372 0.9724 2076609 Maybridge3_002932 CC1=C(C#N)C(C2=C(N1)c3ccccc3C2=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F07 compound treatment 1066749.0 270000.0 0.57 1019730.0 340000.0 0.77 0.9504 0.9891 2076610 Maybridge3_002933 Clc1ccc(cc1)c2c(C#N)c(=O)[nH]c-3c2COc4ccccc43 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F08 compound treatment 1009983.0 213000.0 0.45 1064695.0 385000.0 0.87 0.9376 0.9528 2076611 Maybridge3_002934 c1ccc(nc1)c2nccnc2c3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F09 compound treatment 987989.0 191000.0 0.41 998413.0 318000.0 0.72 0.7981 0.9624 1607073 Maybridge3_002935 Cc1cc(NC(=O)CSc2nc3ccccc3[nH]2)n(n1)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F10 compound treatment 1252669.0 456000.0 0.97 1101527.0 421000.0 0.96 1.3607 1.0 1489868 Maybridge3_002936 COc1ccc(cc1OC)C(=O)CC(=O)Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F11 compound treatment 1141835.0 345000.0 0.73 1458410.0 778000.0 1.77 1.7682 0.9236 2076612 Maybridge3_002937 CC1=Nn2c(nnc2SC1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F12 compound treatment 1369081.0 572000.0 1.21 1472829.0 793000.0 1.8 2.1321 0.9814 1251199 Maybridge3_002938 O=c1cc(oc2ccc(cc12)c3nnn[nH]3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F13 compound treatment 1270890.0 474000.0 1.0 1514395.0 834000.0 1.9 2.0517 0.9559 1625565 Maybridge3_002939 Nc1sc(cc1C(=O)O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F14 compound treatment 1283198.0 486000.0 1.03 1388559.0 708000.0 1.61 1.8679 0.9768 1012288 Maybridge3_002940 NC(C1CCCCC1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F15 compound treatment 1225528.0 429000.0 0.91 1384738.0 705000.0 1.6 1.7753 0.9639 2076613 Maybridge3_002941 Cc1cc(C)c2c(=O)n(sc2n1)C(=O)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F16 compound treatment 1178374.0 381000.0 0.81 1271467.0 591000.0 1.34 1.5225 0.9704 1228625 Maybridge3_002942 COc1cccc(OC)c1CCOC(=O)c2c(F)cccc2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F17 compound treatment 1165621.0 369000.0 0.78 1309382.0 629000.0 1.43 1.5643 0.9596 2076614 Maybridge3_002943 Nc1c(sc2nsc(SCCN3CCOCC3)c12)C(=O)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F18 compound treatment 1071422.0 275000.0 0.58 1394243.0 714000.0 1.62 1.5595 0.9042 2076615 Maybridge3_002944 FC(F)(F)c1ccc(cc1)N2CCCCC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F19 compound treatment 1129555.0 333000.0 0.71 1307347.0 627000.0 1.43 1.507 0.9473 2076616 Maybridge3_002945 NC(=O)CSc1nc(CN2c3ccccc3Sc4ccccc24)n[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F20 compound treatment 1218041.0 421000.0 0.89 1091856.0 412000.0 0.94 1.2932 0.9997 1601566 Maybridge3_002946 CC(CN1CCN(Cc2ccccc2)CC1)N(C(=O)C3CCC3)c4ccccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F21 compound treatment 1036697.0 240000.0 0.51 1151294.0 471000.0 1.07 1.1169 0.942 2076617 Maybridge3_002947 COc1ccc(/C=C(\C#N)/c2cccc(Cl)c2)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F22 compound treatment 1205379.0 408000.0 0.87 1111686.0 432000.0 0.98 1.3061 0.9981 2076618 Maybridge3_002948 O=C(OC1CSSCC1OC(=O)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F23 mock treatment 975673.0 179000.0 0.38 948455.0 268000.0 0.61 0.6993 0.9738 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 F24 mock treatment 644431.0 -152000.0 -0.32 467212.0 -213000.0 -0.48 -0.5709 -0.9807 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G01 compound treatment 518084.0 -279000.0 -0.59 720348.0 40200.0 0.09 -0.3533 -0.5907 2076619 Maybridge3_002949 Cn1nc(cc1NC(=O)c2cccs2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G02 compound treatment 873397.0 76500.0 0.16 981390.0 301000.0 0.68 0.599 0.851 2076620 Maybridge3_002950 CCOC(=O)N1CCC(CC1)NC(=O)c2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G03 compound treatment 974909.0 178000.0 0.38 1077179.0 397000.0 0.9 0.9051 0.9251 1336744 Maybridge3_002951 Cc1cc(on1)c2ccccc2C(=O)Nc3ccccc3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G04 compound treatment 1073240.0 276000.0 0.59 1015356.0 335000.0 0.76 0.9531 0.9916 2076621 Maybridge3_002952 Nc1nnc(o1)c2ccc3nsnc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G05 compound treatment 1110025.0 313000.0 0.66 1077223.0 397000.0 0.9 1.1077 0.9886 1561126 Maybridge3_002953 Cc1nc(N2CCOCC2)c3sc(=S)n(c4ccccc4)c3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G06 compound treatment 1260345.0 463000.0 0.98 1777296.0 1100000.0 2.49 2.4586 0.917 2076622 Maybridge3_002954 FC(F)(F)c1ccc(nc1)N2CCCN(CC2)S(=O)(=O)c3ccc(C#N)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G07 compound treatment 1078388.0 281000.0 0.6 1248114.0 568000.0 1.29 1.3351 0.9385 2076623 Maybridge3_002955 COc1ccc(cc1)C(=O)CN2C(=O)c3ccccc3S2(=O)=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G08 compound treatment 1314980.0 518000.0 1.1 1223636.0 544000.0 1.24 1.6504 0.9983 2076624 Maybridge3_002956 Cc1ccc2cc(NC(=O)C3CN(Cc4ccco4)C(=O)C3)ccc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G09 compound treatment 374264.0 -423000.0 -0.9 321895.0 -358000.0 -0.81 -1.2095 -0.9989 2076625 Maybridge3_002957 CCCc1ccc(cc1)C(=O)NC(=O)c2ccccc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G10 compound treatment 1393396.0 596000.0 1.26 1821752.0 1140000.0 2.6 2.7295 0.9454 2076626 Maybridge3_002958 COc1cccc(Cc2nnc(o2)c3snnc3C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G11 compound treatment 1268255.0 471000.0 1.0 1658427.0 978000.0 2.22 2.2793 0.9348 2076627 Maybridge3_002959 COC(=O)CNC(=O)C1CCC(CC1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G12 compound treatment 1204354.0 407000.0 0.86 1924378.0 1240000.0 2.83 2.6111 0.8828 2076628 Maybridge3_002960 O=c1oc2ccccc2cc1c3ccn[nH]3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G13 compound treatment 1388300.0 591000.0 1.25 1543839.0 864000.0 1.96 2.275 0.9765 2076629 Maybridge3_002961 Cc1nn(nc1C(=O)N2CCCc3ccccc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G14 compound treatment 1442437.0 646000.0 1.37 1806756.0 1130000.0 2.56 2.7789 0.9569 2076630 Maybridge3_002962 O=C(Nc1ccc2OCCOc2c1)c3ccoc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G15 compound treatment 1297700.0 501000.0 1.06 1194965.0 515000.0 1.17 1.5784 0.9988 2076631 Maybridge3_002963 COc1ccc(NC(=O)c2scc(c2N)S(=O)(=O)C(C)C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G16 compound treatment 1507841.0 711000.0 1.51 1544825.0 865000.0 1.97 2.4558 0.9914 2076632 Maybridge3_002964 Cc1nn(nc1C(=O)N2CCC(O)(CC2)c3ccc(Cl)cc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G17 compound treatment 1092509.0 296000.0 0.63 1640366.0 960000.0 2.18 1.9868 0.8748 1537696 Maybridge3_002965 CC1CCc2c(C1)sc3nc(SCC(=O)N)nc(NCc4ccccc4)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G18 compound treatment 1251182.0 454000.0 0.96 1537868.0 858000.0 1.95 2.0599 0.9471 1496557 Maybridge3_002966 O=C(NCc1ccco1)c2cc3ccccc3oc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G19 compound treatment 1302212.0 505000.0 1.07 1291092.0 611000.0 1.39 1.7397 0.9918 2076633 Maybridge3_002967 Cc1nc(sc1C(=O)NC(=O)c2ccccc2O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G20 compound treatment 1298000.0 501000.0 1.06 1216922.0 537000.0 1.22 1.6141 0.9976 2076634 Maybridge3_002968 CC1CCc2c(C#N)c(NC(=O)CSc3nnc[nH]3)sc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G21 compound treatment 1263562.0 467000.0 0.99 1208432.0 528000.0 1.2 1.5488 0.9954 2076635 Maybridge3_002969 CC(=O)Nc1ccc(cc1)c2nc3ccccc3c(=O)[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G22 compound treatment 1072496.0 276000.0 0.58 1118444.0 438000.0 1.0 1.1178 0.9676 2076636 Maybridge3_002970 Cc1cc(NC(=O)CSc2nccn2C)n(n1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G23 mock treatment 965255.0 168000.0 0.36 945634.0 266000.0 0.6 0.6792 0.9685 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 G24 mock treatment 447757.0 -349000.0 -0.74 480799.0 -199000.0 -0.45 -0.8438 -0.9723 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H01 compound treatment 492947.0 -304000.0 -0.64 747335.0 67200.0 0.15 -0.3476 -0.5249 2076637 Maybridge3_002971 CCN(CC)c1ncnc2n(Cc3ccccc3)nnc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H02 compound treatment 1042449.0 246000.0 0.52 1077908.0 398000.0 0.9 1.0076 0.9656 2076638 Maybridge3_002972 CN1CCN(CC1)C(=O)Oc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H03 compound treatment 1086612.0 290000.0 0.61 1098488.0 418000.0 0.95 1.1068 0.9776 2076639 Maybridge3_002973 CC(NC(=O)c1ccc(Cl)cc1Cl)C(=O)NC2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H04 compound treatment 947799.0 151000.0 0.32 1059927.0 380000.0 0.86 0.8368 0.9087 2076640 Maybridge3_002974 CCCC(=O)OC1C(Oc2ccccc2C1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H05 compound treatment 1077063.0 280000.0 0.59 1263590.0 583000.0 1.33 1.3579 0.9343 2076641 Maybridge3_002975 CCOC(=O)c1cnn2c(=O)c3CCCCc3[nH]c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H06 compound treatment 1113858.0 317000.0 0.67 1612990.0 933000.0 2.12 1.9748 0.8876 1664247 Maybridge3_002976 CC(=O)Nc1ccc(NC(=O)C2CC2(C)C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H07 compound treatment 1260927.0 464000.0 0.98 1376518.0 696000.0 1.58 1.8151 0.9738 1879051 Maybridge3_002977 CCOC(=O)c1cnn2c(=O)c3CCCc3[nH]c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H08 compound treatment 1266585.0 470000.0 1.0 1274961.0 595000.0 1.35 1.6603 0.9887 1047844 Maybridge3_002978 OC1(Cc2ccccc2)CCNCC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H09 compound treatment 1314739.0 518000.0 1.1 1557777.0 878000.0 2.0 2.1872 0.9604 1393091 Maybridge3_002979 O=c1[nH]c-2c(CCc3ccccc32)c(c1C#N)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H10 compound treatment 1605572.0 809000.0 1.71 1712777.0 1030000.0 2.35 2.8723 0.9881 2076642 Maybridge3_002980 OC(=O)CCSc1cccc(c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H11 compound treatment 1426193.0 629000.0 1.33 1482629.0 803000.0 1.82 2.2334 0.9882 2076643 Maybridge3_002981 C1Sc2nnc(c3ccccc3)n2N=C1c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H12 compound treatment 1325246.0 528000.0 1.12 2262862.0 1580000.0 3.6 3.3365 0.8853 1053054 Maybridge3_002982 O=c1cc(oc2ccccc12)c3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H13 compound treatment 1591437.0 795000.0 1.68 1988596.0 1310000.0 2.97 3.2946 0.9637 2076644 Maybridge3_002983 Cc1ccc(cc1)N2CC(=O)Nc3c(sc4nc(C)cc(C)c34)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H14 compound treatment 1486888.0 690000.0 1.46 1733970.0 1050000.0 2.4 2.7285 0.972 2076645 Maybridge3_002984 CC(CCC(=O)O)C1CCC2C3C(CC(=O)C12C)C4(C)CCC(=O)CC4CC3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H15 compound treatment 1170648.0 374000.0 0.79 1682639.0 1000000.0 2.28 2.1719 0.9001 2076646 Maybridge3_002985 CC(=O)n1sc2nc(C)cc(C)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H16 compound treatment 1279590.0 483000.0 1.02 1606907.0 927000.0 2.11 2.2135 0.945 2076647 Maybridge3_002986 CC1(C)C2CCC1(C)C(C2)NS(=O)(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H17 compound treatment 1535647.0 739000.0 1.57 1481647.0 802000.0 1.82 2.3959 0.9972 2076648 Maybridge3_002987 Nc1c(C#N)sc2nnc(c3ccncc3)n12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H18 compound treatment 1292110.0 495000.0 1.05 1377072.0 697000.0 1.58 1.8628 0.98 2076649 Maybridge3_002988 FC(F)(F)c1ccc(cc1)n2ccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H19 compound treatment 1372854.0 576000.0 1.22 1701572.0 1020000.0 2.32 2.5055 0.9549 2076650 Maybridge3_002989 Cc1cc(C)c2c3NC(=O)CN(C(=O)c3oc2n1)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H20 compound treatment 1256804.0 460000.0 0.97 1263509.0 583000.0 1.33 1.6273 0.9885 1524786 Maybridge3_002990 O=C(Nc1cccc2[nH]ccc12)C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H21 compound treatment 1224505.0 428000.0 0.91 1249101.0 569000.0 1.29 1.5557 0.9849 2076651 Maybridge3_002991 CCOc1ccc(NC(=O)/C=N/O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H22 compound treatment 1153822.0 357000.0 0.76 1191593.0 511000.0 1.16 1.3573 0.9783 1915825 Maybridge3_002992 O=C(Nc1ccc2ccccc2c1)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H23 mock treatment 1093937.0 297000.0 0.63 1036881.0 357000.0 0.81 1.0188 0.9922 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 H24 mock treatment 715395.0 -81500.0 -0.17 577888.0 -102000.0 -0.23 -0.2866 -0.9893 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I01 compound treatment 579187.0 -218000.0 -0.46 767142.0 87000.0 0.2 -0.1865 -0.3714 2076652 Maybridge3_002993 Cc1cc(no1)C(=O)Nc2cc(nn2C)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I02 compound treatment 1147852.0 351000.0 0.74 1077019.0 397000.0 0.9 1.1641 0.9954 2076653 Maybridge3_002994 Cc1c(cnn1c2ccccc2)S(=O)(=O)N3CCCc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I03 compound treatment 1129656.0 333000.0 0.71 1100191.0 420000.0 0.96 1.1741 0.9889 2076654 Maybridge3_002995 O=C(OCC1CC(=NO1)c2ccccc2)c3ccc4ccccc4n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I04 compound treatment 1152892.0 356000.0 0.75 1083242.0 403000.0 0.92 1.1817 0.9953 1527073 Maybridge3_002996 O=C(NCC1COc2ccccc2O1)C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I05 compound treatment 1269418.0 473000.0 1.0 1169914.0 490000.0 1.11 1.4957 0.9986 2076655 Maybridge3_002997 C=CCn1c(Sc2ncnc3n(CC=C)c(=S)sc23)nnc1c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I06 compound treatment 1526558.0 730000.0 1.55 1186299.0 506000.0 1.15 1.9075 0.9894 2076656 Maybridge3_002998 Cc1ccc(CNS(=O)(=O)c2cccs2)n1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I07 compound treatment 1442717.0 646000.0 1.37 1237565.0 557000.0 1.27 1.8642 0.9993 2076657 Maybridge3_002999 O=C1N(CC2CC2)S(=O)(=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I08 compound treatment 1627428.0 831000.0 1.76 1303189.0 623000.0 1.42 2.2466 0.9942 2076658 Maybridge3_003000 OC(=O)CCCC(=O)N1CCCN(CC1)c2ccc(cn2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I09 compound treatment 952798.0 156000.0 0.33 877316.0 197000.0 0.45 0.5507 0.9887 2076659 Maybridge3_003001 CCc1ccc(cc1)C(=O)NC(=O)c2ccccc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I10 compound treatment 1384001.0 587000.0 1.24 1382803.0 703000.0 1.6 2.0097 0.9924 2076660 Maybridge3_003002 COc1cccc(Cc2nnc(o2)c3ccc4nsnc4c3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I11 compound treatment 1448209.0 651000.0 1.38 1294595.0 614000.0 1.4 1.9642 1.0 2076661 Maybridge3_003003 Clc1ccc(cc1)C2CCC(CC2)C(=O)NCc3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I12 compound treatment 1296244.0 499000.0 1.06 1424219.0 744000.0 1.69 1.9447 0.9745 1085295 Maybridge3_003004 Nc1ncnc2n(CCc3ccccc3)cnc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I13 compound treatment 1531988.0 735000.0 1.56 1227918.0 548000.0 1.25 1.9826 0.9938 2076662 Maybridge3_003005 COC(=O)c1c(C)oc(C)c1S(=O)(=O)N2CCCc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I14 compound treatment 1427640.0 631000.0 1.34 1104766.0 425000.0 0.97 1.6281 0.9872 2076663 Maybridge3_003006 O=C(Nc1ccc2OCCOc2c1)c3ccc4nsnc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I15 compound treatment 1490280.0 693000.0 1.47 1319851.0 640000.0 1.45 2.0678 1.0 1657296 Maybridge3_003007 Cc1cc(C)c2c(N)c(sc2n1)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I16 compound treatment 1481258.0 684000.0 1.45 1561755.0 882000.0 2.0 2.4432 0.9874 2076664 Maybridge3_003008 COC(=O)c1ccc(Oc2ccc(cc2)C3SCCS3)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I17 compound treatment 1800498.0 1000000.0 2.13 1539117.0 859000.0 1.95 2.8854 0.9991 1416967 Maybridge3_003009 O=C(COc1ccccc1)N2c3ccccc3Sc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I18 compound treatment 1041234.0 244000.0 0.52 1345999.0 666000.0 1.51 1.4367 0.8979 2076665 Maybridge3_003010 CC(NCCn1cnc2c(N)ncnc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I19 compound treatment 1093375.0 296000.0 0.63 915256.0 235000.0 0.53 0.8224 0.9968 2076666 Maybridge3_003011 Oc1ccccc1C(=O)NC(=O)c2ccoc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I20 compound treatment 1410712.0 614000.0 1.3 1172575.0 492000.0 1.12 1.7118 0.9972 2076667 Maybridge3_003012 FC(F)(F)c1cccc(Nc2cc(nc3ncnn23)c4ccccc4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I21 compound treatment 1292212.0 495000.0 1.05 1107053.0 427000.0 0.97 1.4288 0.9992 2076668 Maybridge3_003013 Oc1ccccc1c2nc(n[nH]2)c3ccc4OCCc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I22 compound treatment 1381783.0 585000.0 1.24 1174561.0 494000.0 1.12 1.6716 0.9988 2076669 Maybridge3_003014 CCC1C2=C(CC(C)(C)CC2=O)Nc3c1c(C)nn3c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I23 mock treatment 1192684.0 396000.0 0.84 1049108.0 369000.0 0.84 1.1865 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 I24 mock treatment 757051.0 -39900.0 -0.08 541267.0 -139000.0 -0.32 -0.283 -0.8659 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J01 compound treatment 608146.0 -189000.0 -0.4 842604.0 162000.0 0.37 -0.0218 -0.04 2076670 Maybridge3_003015 Clc1ccccc1Cn2nnc3c(ncnc23)N4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J02 compound treatment 928573.0 132000.0 0.28 1069953.0 390000.0 0.89 0.8241 0.8869 2076671 Maybridge3_003016 COCOc1ccc(cc1)C(=O)CC(=O)c2ccccc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J03 compound treatment 1183451.0 387000.0 0.82 1021354.0 341000.0 0.78 1.128 0.9996 2076672 Maybridge3_003017 CC(NC(=O)c1ccc(Cl)cc1Cl)C(=O)NCc2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J04 compound treatment 1005218.0 208000.0 0.44 1096308.0 416000.0 0.95 0.9813 0.9398 2076673 Maybridge3_003018 O=C1/C(=C\c2ccccc2)/Sc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J05 compound treatment 1076892.0 280000.0 0.59 1115150.0 435000.0 0.99 1.1191 0.9702 1151675 Maybridge3_003019 CCOC(=O)c1cnn2c(=O)cc(C)[nH]c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J06 compound treatment 1276527.0 480000.0 1.02 1321306.0 641000.0 1.46 1.7497 0.9845 1540118 Maybridge3_003020 O=C(OCC1c2ccccc2-c3ccccc13)ON4C(=O)CCC4=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J07 compound treatment 1345277.0 548000.0 1.16 1219851.0 540000.0 1.23 1.6897 0.9996 2076674 Maybridge3_003021 CC(=O)Oc1c(c2ccccc2)c(=O)n3CCc4cccc1c43 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J08 compound treatment 1293019.0 496000.0 1.05 1216805.0 537000.0 1.22 1.6065 0.9973 2076675 Maybridge3_003022 CS/C(=N\N)/NC1(CC2CC3CC(C2)C1)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J09 compound treatment 1291141.0 494000.0 1.05 1238474.0 558000.0 1.27 1.6385 0.9955 2076676 Maybridge3_003023 CCn1c(SCC(=O)N2CCCc3ccccc23)nnc1c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J10 compound treatment 1709900.0 913000.0 1.94 1267348.0 587000.0 1.34 2.3126 0.9836 1230905 Maybridge3_003024 CNC(=O)c1ccccc1SCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J11 compound treatment 1438082.0 641000.0 1.36 1411855.0 732000.0 1.66 2.1375 0.995 2076677 Maybridge3_003025 O=C(CSc1nc2ccccc2s1)Nc3c(C#N)cnn3c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J12 compound treatment 1795176.0 998000.0 2.12 1533754.0 854000.0 1.94 2.8688 0.9991 1704321 Maybridge3_003026 CCOC(=O)COc1ccc2c(=O)cc(oc2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J13 compound treatment 1582087.0 785000.0 1.66 1297892.0 618000.0 1.4 2.1701 0.9964 2076678 Maybridge3_003027 C1Sc2ccccc2-n3c(nnc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J14 compound treatment 1635586.0 839000.0 1.78 1282061.0 602000.0 1.37 2.2249 0.9916 1007376 Maybridge3_003028 OC(=O)c1ccc(F)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J15 compound treatment 1579055.0 782000.0 1.66 1310206.0 630000.0 1.43 2.1854 0.9973 2076679 Maybridge3_003029 COc1cc(/C=C\2/N=C(NC2=O)c3ccccc3)cc(OC)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J16 compound treatment 1627819.0 831000.0 1.76 1523925.0 844000.0 1.92 2.6021 0.9991 2076680 Maybridge3_003030 Cc1ccc(cc1)S(=O)(=O)NC2CC3CCC2(C)C3(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J17 compound treatment 1525781.0 729000.0 1.55 1323319.0 643000.0 1.46 2.1266 0.9996 2076681 Maybridge3_003031 O=C1CSc2nnc(c3ccncc3)n12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J18 compound treatment 1568129.0 771000.0 1.63 1209347.0 529000.0 1.2 2.0069 0.9886 2076682 Maybridge3_003032 CCOC(=O)c1sc(N)nc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J19 compound treatment 1375635.0 579000.0 1.23 1221963.0 542000.0 1.23 1.7386 1.0 2076683 Maybridge3_003033 O=C(Nc1scc2c1c(=O)oc3ccccc23)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J20 compound treatment 1328647.0 532000.0 1.13 1114373.0 434000.0 0.99 1.4952 0.9978 2076684 Maybridge3_003034 FC(F)(F)c1cccc(c1)C(=O)Nc2cccc3[nH]ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J21 compound treatment 1318457.0 522000.0 1.11 1165499.0 485000.0 1.1 1.5621 1.0 2076685 Maybridge3_003035 O/C(=C\C(=O)c1ccc(Br)cc1)/C(=O)Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J22 compound treatment 1250016.0 453000.0 0.96 1002501.0 322000.0 0.73 1.1975 0.9911 1198285 Maybridge3_003036 Fc1cccc(c1)C(=O)N(Cc2ccccc2)C(=C)C3CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J23 mock treatment 1137470.0 341000.0 0.72 835188.0 155000.0 0.35 0.7598 0.9457 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 J24 mock treatment 608900.0 -188000.0 -0.4 563468.0 -117000.0 -0.27 -0.4694 -0.9804 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K01 compound treatment 497459.0 -299000.0 -0.63 711130.0 31000.0 0.07 -0.3991 -0.6248 2076686 Maybridge3_003037 CCOC(=O)c1cnn(C(=O)c2ccc(cc2)C(F)(F)F)c1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K02 compound treatment 1221069.0 424000.0 0.9 884352.0 204000.0 0.46 0.9641 0.9527 2076687 Maybridge3_003038 O=S(=O)(N1CCCc2ccccc12)c3ccc(cc3)n4cccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K03 compound treatment 1193050.0 396000.0 0.84 934946.0 255000.0 0.58 1.0035 0.9836 1306563 Maybridge3_003039 CSc1nnc2NCCCn12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K04 compound treatment 1369877.0 573000.0 1.21 1024578.0 344000.0 0.78 1.4126 0.9775 2076688 Maybridge3_003040 Clc1cc(C(=O)NCC2COc3ccccc3O2)c(Cl)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K05 compound treatment 1316296.0 519000.0 1.1 1115113.0 435000.0 0.99 1.4779 0.9986 1717070 Maybridge3_003041 Cc1nn(c2ccccc2)c3nc(N)c(cc13)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K06 compound treatment 1434248.0 637000.0 1.35 1056684.0 377000.0 0.86 1.5608 0.9758 2076689 Maybridge3_003042 Cc1ccc(CNS(=O)(=O)c2ccccc2)n1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K07 compound treatment 1528573.0 732000.0 1.55 953980.0 274000.0 0.62 1.537 0.9196 2076690 Maybridge3_003043 O=C1N(Cc2ccc(cc2)c3csnn3)S(=O)(=O)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K08 compound treatment 1411330.0 614000.0 1.3 1041072.0 361000.0 0.82 1.5013 0.9752 2076691 Maybridge3_003044 FC(F)(F)c1ccc(nc1)N2CCCN(CC2)S(=O)(=O)c3ccc4OCCc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K09 compound treatment 1385910.0 589000.0 1.25 1045706.0 366000.0 0.83 1.4706 0.9804 1178648 Maybridge3_003045 Cc1ccc(cc1)S(=O)(=O)Nc2cccc3nnc(C)cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K10 compound treatment 1589682.0 793000.0 1.68 988994.0 309000.0 0.7 1.6849 0.9251 2076692 Maybridge3_003046 OC(=O)CCC(=O)Nc1ccc(Oc2c(Cl)cccc2Cl)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K11 compound treatment 1689035.0 892000.0 1.89 1186644.0 507000.0 1.15 2.1516 0.9717 2076693 Maybridge3_003047 CC(C)(C)C(=O)OCc1nc(cs1)c2ccc3OCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K12 compound treatment 1989335.0 1190000.0 2.53 1023495.0 343000.0 0.78 2.3395 0.8843 2076694 Maybridge3_003048 CCOC(=O)c1cnn(C(=O)Cc2ccsc2)c1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K13 compound treatment 1828114.0 1030000.0 2.19 985754.0 306000.0 0.69 2.0371 0.8881 1502073 Maybridge3_003049 O=S(=O)(N1CCCc2ccccc12)c3cccc4nsnc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K14 compound treatment 1014144.0 217000.0 0.46 1101319.0 421000.0 0.96 1.0028 0.9437 2076695 Maybridge3_003050 Cc1cc(nn1C(C)(C)C)C(=O)Nc2ccc3OCCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K15 compound treatment 1796019.0 999000.0 2.12 1116605.0 436000.0 0.99 2.1994 0.9403 1520276 Maybridge3_003051 N#CCOc1nc(cc(c2ccco2)c1C#N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K16 compound treatment 1717232.0 920000.0 1.95 952886.0 273000.0 0.62 1.8181 0.8881 2076696 Maybridge3_003052 O/N=C\1/CCCCC1Cn2ccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K17 compound treatment 1540069.0 743000.0 1.58 1014451.0 334000.0 0.76 1.6515 0.9441 1141744 Maybridge3_003053 O=C(CSc1nnc[nH]1)N2c3ccccc3Sc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K18 compound treatment 1539162.0 742000.0 1.57 1149106.0 469000.0 1.07 1.8666 0.982 1026368 Maybridge3_003054 c1ccc2sc(nc2c1)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K19 compound treatment 1634264.0 837000.0 1.78 1339135.0 659000.0 1.5 2.3147 0.9964 2076697 Maybridge3_003055 Oc1ccccc1C(=O)NC(=O)c2ccc3OCCc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K20 compound treatment 1658242.0 861000.0 1.83 1363780.0 684000.0 1.55 2.3902 0.9968 2076698 Maybridge3_003056 Cc1ccc(Nc2cc(nc3ncnn23)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K21 compound treatment 1615657.0 819000.0 1.74 1027473.0 347000.0 0.79 1.7857 0.9365 2076699 Maybridge3_003057 COc1ccc(cc1OC)c2nc(=O)c3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K22 compound treatment 1361961.0 565000.0 1.2 633664.0 -46500.0 -0.11 0.7723 0.6423 2076700 Maybridge3_003058 Cc1cc(C)c2c(n1)sc3c(SCC=C)ncnc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K23 mock treatment 1218364.0 421000.0 0.89 612786.0 -67300.0 -0.15 0.5235 0.5775 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 K24 mock treatment 765138.0 -31800.0 -0.07 435012.0 -245000.0 -0.56 -0.4417 -0.7869 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L01 compound treatment 568168.0 -229000.0 -0.48 749191.0 69100.0 0.16 -0.2319 -0.4549 2076701 Maybridge3_003059 Clc1ccc(cc1)n2cc(C#N)c(n2)C(=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L02 compound treatment 974627.0 178000.0 0.38 936793.0 257000.0 0.58 0.679 0.9776 1467534 Maybridge3_003060 Cc1ccc(cc1)c2cc(=O)c3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L03 compound treatment 972871.0 176000.0 0.37 1014893.0 335000.0 0.76 0.8019 0.9461 2076702 Maybridge3_003061 CC(NC(=O)c1ccc(Cl)cc1Cl)C(=O)NCc2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L04 compound treatment 1010302.0 213000.0 0.45 1021903.0 342000.0 0.78 0.8693 0.9669 2076703 Maybridge3_003062 Cc1ccccc1/C=C\2/Sc3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L05 compound treatment 1083416.0 287000.0 0.61 1231346.0 551000.0 1.25 1.3156 0.9447 2076704 Maybridge3_003063 CCOC(=O)c1cnn2c(=O)cc([nH]c12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L06 compound treatment 1151197.0 354000.0 0.75 1318888.0 639000.0 1.45 1.558 0.9529 1723317 Maybridge3_003064 COC(=O)C(Cc1ccccc1)NC(=O)c2cccc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L07 compound treatment 1221813.0 425000.0 0.9 1035921.0 356000.0 0.81 1.2089 0.9986 2076705 Maybridge3_003065 Clc1ccc(Oc2ncnc3n(Cc4ccccc4)nnc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L08 compound treatment 1332554.0 536000.0 1.14 1251632.0 572000.0 1.3 1.7217 0.9977 2076706 Maybridge3_003066 Clc1ccc(cc1)C(=O)/C=C/2\SCC(=O)N2c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L09 compound treatment 1239990.0 443000.0 0.94 1178167.0 498000.0 1.13 1.4649 0.9957 2076707 Maybridge3_003067 Nc1nc(SCc2ccc(Cl)cc2)ncc1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L10 compound treatment 1354096.0 557000.0 1.18 1337710.0 658000.0 1.5 1.8924 0.9932 1128028 Maybridge3_003068 OC(=O)CCSc1cccc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L11 compound treatment 1537402.0 740000.0 1.57 1368965.0 689000.0 1.57 2.2174 1.0 2076708 Maybridge3_003069 Clc1ccccc1CSc2nnc3NCCCn23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L12 compound treatment 1471136.0 674000.0 1.43 1489801.0 810000.0 1.84 2.3123 0.9922 1041430 Maybridge3_003070 CC(=O)Nc1c(oc2ccccc2c1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L13 compound treatment 1578312.0 781000.0 1.66 1175754.0 496000.0 1.13 1.9681 0.9824 2076709 Maybridge3_003071 Cc1nc2sc(cc2c(=O)o1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L14 compound treatment 1540340.0 743000.0 1.58 1271009.0 591000.0 1.34 2.0643 0.9968 2076710 Maybridge3_003072 OC(=O)CCCCc1cccs1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L15 compound treatment 1393425.0 597000.0 1.26 1133324.0 453000.0 1.03 1.6228 0.9948 2076711 Maybridge3_003073 O=c1[nH]cnc2sc(cc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L16 compound treatment 1312308.0 515000.0 1.09 1192376.0 512000.0 1.16 1.5961 0.9995 1524655 Maybridge3_003074 CC(C)C1CCC(C)CC1NC(=O)c2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L17 compound treatment 1453424.0 657000.0 1.39 1116822.0 437000.0 0.99 1.6862 0.9863 2076712 Maybridge3_003075 Nc1ncnc2nc(ncc12)N3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L18 compound treatment 1344601.0 548000.0 1.16 1033198.0 353000.0 0.8 1.3886 0.9838 1233522 Maybridge3_003076 CC(=O)Nc1ccc(cc1)S(=O)(=O)NC2C(C)(C)C3CCC2(C)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L19 compound treatment 1547709.0 751000.0 1.59 1202492.0 522000.0 1.19 1.9652 0.9896 2076713 Maybridge3_003077 NS(=O)(=O)c1ccc(NC(=O)CN2CCCc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L20 compound treatment 1381371.0 584000.0 1.24 1170021.0 490000.0 1.11 1.6637 0.9986 1696824 Maybridge3_003078 COc1ccccc1N2CCN(CC2)C(=O)C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L21 compound treatment 1554866.0 758000.0 1.61 1084737.0 405000.0 0.92 1.7867 0.965 1733585 Maybridge3_003079 COc1ccc(cc1OC)C(=O)Cc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L22 compound treatment 1381416.0 585000.0 1.24 1273169.0 593000.0 1.35 1.8296 0.9991 2076714 Maybridge3_003080 CCOC(=O)CSc1nnnn1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L23 mock treatment 1334020.0 537000.0 1.14 1293930.0 614000.0 1.4 1.7919 0.9949 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 L24 mock treatment 757219.0 -39700.0 -0.08 605957.0 -74200.0 -0.17 -0.1787 -0.9484 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M01 compound treatment 568434.0 -228000.0 -0.48 614528.0 -65600.0 -0.15 -0.448 -0.8839 2076715 Maybridge3_003081 OC(=O)COCC(=O)N1CCN(CC1)C2c3ccccc3-c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M02 compound treatment 1129629.0 333000.0 0.71 969035.0 289000.0 0.66 0.9632 0.9994 1671891 Maybridge3_003082 OC(=O)c1ccccc1C(=O)N2CCCc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M03 compound treatment 1078650.0 282000.0 0.6 1045158.0 365000.0 0.83 1.0092 0.987 2076716 Maybridge3_003083 CCOc1ncnc2sc3CCCCc3c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M04 compound treatment 1142015.0 345000.0 0.73 1086168.0 406000.0 0.92 1.1701 0.9934 2076717 Maybridge3_003084 Cc1nnsc1C(=O)NCC2COc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M05 compound treatment 1123543.0 327000.0 0.69 1187073.0 507000.0 1.15 1.3046 0.9703 1603526 Maybridge3_003085 Cn1ccnc1SCC(=O)N2c3ccccc3Sc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M06 compound treatment 1152611.0 356000.0 0.75 1186140.0 506000.0 1.15 1.3467 0.979 2076718 Maybridge3_003086 Fc1ccc(CN2CC(CC2=O)C(=O)NCc3ccc4OCOc4c3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M07 compound treatment 1143579.0 347000.0 0.73 1062928.0 383000.0 0.87 1.1351 0.9965 2076719 Maybridge3_003087 Oc1ccccc1C(=O)NC(=O)C2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M08 compound treatment 1134913.0 338000.0 0.72 1048021.0 368000.0 0.84 1.0981 0.997 2076720 Maybridge3_003088 CC(C)S(=O)(=O)c1csc(C(=O)Nc2ccc(F)cc2)c1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M09 compound treatment 1164229.0 367000.0 0.78 1174278.0 494000.0 1.12 1.345 0.984 2076721 Maybridge3_003089 Fc1ccc(cc1)C(=O)CN2C(=O)CCC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M10 compound treatment 1085169.0 288000.0 0.61 1192674.0 513000.0 1.17 1.2561 0.9546 2076722 Maybridge3_003090 OC(=O)CSCC(=O)Nc1ccc(Oc2c(Cl)cccc2Cl)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M11 compound treatment 1044602.0 248000.0 0.53 944300.0 264000.0 0.6 0.796 0.9978 1444526 Maybridge3_003091 CC(C)(C)C(=O)OCc1nc(cs1)c2ccc(O)c(O)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M12 compound treatment 1104004.0 307000.0 0.65 1200511.0 520000.0 1.18 1.2969 0.9604 2076723 Maybridge3_003092 Cc1nc(n[nH]1)c2cccc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M13 compound treatment 1299889.0 503000.0 1.07 1104686.0 425000.0 0.97 1.4365 0.9988 2076724 Maybridge3_003093 Cc1onc(c1C(=O)NC(CN2CCOCC2)c3ccccc3)c4c(F)cccc4Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M14 compound treatment 1224260.0 427000.0 0.91 1285991.0 606000.0 1.38 1.6146 0.9793 2076725 Maybridge3_003094 O=C(Nc1ccc2OCCOc2c1)c3ncoc3c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M15 compound treatment 1424831.0 628000.0 1.33 1154071.0 474000.0 1.08 1.7032 0.9945 1385209 Maybridge3_003095 CCOC(=O)COc1nc(cc(c2ccco2)c1C#N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M16 compound treatment 1201821.0 405000.0 0.86 1021439.0 341000.0 0.78 1.1557 0.9987 1628910 Maybridge3_003096 OC(=O)Cn1c2ccccc2c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M17 compound treatment 1141873.0 345000.0 0.73 1146467.0 466000.0 1.06 1.2668 0.9836 2076726 Maybridge3_003097 Brc1ccc(cc1)C(=O)CSc2nnc(o2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M18 compound treatment 1246445.0 450000.0 0.95 1146896.0 467000.0 1.06 1.4243 0.9986 2076727 Maybridge3_003098 Nc1cc(Cl)ccc1Nc2ccncc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M19 compound treatment 1388934.0 592000.0 1.26 1021439.0 341000.0 0.78 1.4362 0.9733 2076728 Maybridge3_003099 Cc1nnsc1C(=O)NC(=O)c2ccccc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M20 compound treatment 1273848.0 477000.0 1.01 1118182.0 438000.0 1.0 1.4192 1.0 2076729 Maybridge3_003100 Clc1ccc(Nc2cc(nc3ncnn23)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M21 compound treatment 1404195.0 607000.0 1.29 1088445.0 408000.0 0.93 1.5668 0.9871 2076730 Maybridge3_003101 FC(F)(F)c1ccccc1NS(=O)(=O)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M22 compound treatment 1333055.0 536000.0 1.14 1007803.0 328000.0 0.74 1.3305 0.979 2076731 Maybridge3_003102 Cc1cc(C)c2c(n1)sc3c(Sc4nccn4C)ncnc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M23 mock treatment 1201689.0 405000.0 0.86 873360.0 193000.0 0.44 0.9174 0.9517 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 M24 mock treatment 660091.0 -137000.0 -0.29 581607.0 -98500.0 -0.22 -0.3635 -0.9918 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N01 compound treatment 439516.0 -357000.0 -0.76 650296.0 -29800.0 -0.07 -0.5837 -0.7673 2076732 Maybridge3_003103 Cc1ccc(cc1)n2cc(C#N)c(n2)C(=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N02 compound treatment 1055380.0 258000.0 0.55 1028248.0 348000.0 0.79 0.9471 0.9839 1329051 Maybridge3_003104 COc1ccc(cc1)c2cc(=O)c3cc(F)ccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N03 compound treatment 1104423.0 308000.0 0.65 1103538.0 423000.0 0.96 1.1417 0.982 2076733 Maybridge3_003105 CC(=O)Nc1c(sc2nc(C)cc(C)c12)C(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N04 compound treatment 1180976.0 384000.0 0.81 1246035.0 566000.0 1.29 1.4855 0.9756 2076734 Maybridge3_003106 Cc1cccc(/C=C\2/Sc3ccccc3C2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N05 compound treatment 972721.0 176000.0 0.37 1192145.0 512000.0 1.16 1.0867 0.889 1820764 Maybridge3_003107 O=C(CSc1ccccc1)N2CCc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N06 compound treatment 967207.0 170000.0 0.36 1401515.0 721000.0 1.64 1.415 0.8426 2076735 Maybridge3_003108 CCOC(=O)c1c(NC(=O)C(F)(F)F)sc2CCCCc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N07 compound treatment 956842.0 160000.0 0.34 985064.0 305000.0 0.69 0.73 0.9459 2076736 Maybridge3_003109 Nc1nc(Nc2cccc(c2)C(F)(F)F)ncc1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N08 compound treatment 1041948.0 245000.0 0.52 1318668.0 639000.0 1.45 1.3939 0.904 1424787 Maybridge3_003110 CCOC(=O)CN1C(=O)C2(OCCO2)c3cc(Br)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N09 compound treatment 956130.0 159000.0 0.34 1197094.0 517000.0 1.18 1.0698 0.8748 2076737 Maybridge3_003111 Nc1nc(Sc2nc3ccccc3s2)ncc1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N10 compound treatment 1023717.0 227000.0 0.48 1115265.0 435000.0 0.99 1.0395 0.9451 1560631 Maybridge3_003112 CNS(=O)(=O)c1ccccc1Sc2cccc3cccc(C(=O)O)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N11 compound treatment 1108694.0 312000.0 0.66 1227834.0 548000.0 1.25 1.3479 0.9561 2076738 Maybridge3_003113 O=C(N1CCCn2c(SCc3ccccc3)nnc12)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N12 compound treatment 1261600.0 465000.0 0.99 1460536.0 780000.0 1.77 1.9512 0.9615 1377352 Maybridge3_003114 Nc1c(oc2ccccc2c1=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N13 compound treatment 955687.0 159000.0 0.34 1250055.0 570000.0 1.3 1.1542 0.8622 2076739 Maybridge3_003115 Nc1c(C#N)cnn1c2ncnc3sc4CCCCc4c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N14 compound treatment 1106866.0 310000.0 0.66 1128326.0 448000.0 1.02 1.1852 0.9775 1523192 Maybridge3_003116 CN(C)c1ccc(cc1)C2Nc3[nH]nc(C)c3C4=C2C(=O)CC(C)(C)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N15 compound treatment 1117964.0 321000.0 0.68 1197874.0 518000.0 1.18 1.3136 0.9661 2076740 Maybridge3_003117 CCOC(=O)c1cc(sc1NC(=O)CSc2nccn2C)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N16 compound treatment 1141097.0 344000.0 0.73 1290611.0 610000.0 1.39 1.4974 0.9549 2076741 Maybridge3_003118 CCOC(NC(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N17 compound treatment 1090279.0 293000.0 0.62 1361490.0 681000.0 1.55 1.5351 0.9196 1411244 Maybridge3_003119 C1CCN(C1)c2ncnc3n(ncc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N18 compound treatment 1115801.0 319000.0 0.68 1465916.0 786000.0 1.79 1.7413 0.9116 1382805 Maybridge3_003120 CC1(C)C(NS(=O)(=O)c2ccc(F)cc2)C3(C)CCC1C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N19 compound treatment 1361814.0 565000.0 1.2 1414898.0 735000.0 1.67 2.0281 0.9867 2076742 Maybridge3_003121 NS(=O)(=O)c1ccc(NC(=O)CN2CCc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N20 compound treatment 1300794.0 504000.0 1.07 1353254.0 673000.0 1.53 1.8375 0.9845 1501899 Maybridge3_003122 COc1ccccc1N2CCN(CC2)C(=O)c3ccc(Cl)cc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N21 compound treatment 1166795.0 370000.0 0.78 1093091.0 413000.0 0.94 1.2184 0.996 1170387 Maybridge3_003123 CCOC(=O)C1=C(C)NCC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N22 compound treatment 1242122.0 445000.0 0.94 1163400.0 483000.0 1.1 1.4443 0.9971 1551452 Maybridge3_003124 OC(C1CCCN1)(c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N23 mock treatment 1080290.0 283000.0 0.6 1003543.0 323000.0 0.74 0.9447 0.995 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 N24 mock treatment 571168.0 -226000.0 -0.48 639696.0 -40400.0 -0.09 -0.4034 -0.8278 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O01 compound treatment 439609.0 -357000.0 -0.76 565596.0 -115000.0 -0.26 -0.7197 -0.8986 2076743 Maybridge3_003125 FC(F)(F)c1ccc(cc1)c2nnc(o2)c3ccc4nsnc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O02 compound treatment 885968.0 89100.0 0.19 1000519.0 320000.0 0.73 0.6486 0.8619 2076744 Maybridge3_003126 FC(F)(F)c1ccccc1NC(=O)c2ccsc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O03 compound treatment 1151905.0 355000.0 0.75 1042078.0 362000.0 0.82 1.114 0.999 1273536 Maybridge3_003127 COc1cccc(c1)C2C(=C(N)Oc3c2c(=O)oc4ccccc34)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O04 compound treatment 1119426.0 323000.0 0.68 1066399.0 386000.0 0.88 1.1044 0.9923 1467853 Maybridge3_003128 O=S(=O)(NCC1COc2ccccc2O1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O05 compound treatment 1183795.0 387000.0 0.82 1086091.0 406000.0 0.92 1.2326 0.9983 2076745 Maybridge3_003129 Cc1nc(Sc2nnc[nH]2)c3sc(=S)n(c4ccccc4)c3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O06 compound treatment 1433118.0 636000.0 1.35 1146169.0 466000.0 1.06 1.7029 0.9929 2076746 Maybridge3_003130 Clc1ccc(CCN2CC(CC2=O)C(=O)NCc3ccc4OCOc4c3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O07 compound treatment 1190168.0 393000.0 0.83 1012550.0 332000.0 0.76 1.1239 0.9988 2076747 Maybridge3_003131 Cc1ccc(cc1)C(=O)NC(=O)c2ccccc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O08 compound treatment 1175484.0 379000.0 0.8 1078078.0 398000.0 0.9 1.2072 0.9982 2076748 Maybridge3_003132 O=S(=O)(N1CCOCC1)c2ccc(CN3CCOCC3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O09 compound treatment 1375966.0 579000.0 1.23 1183070.0 503000.0 1.14 1.6766 0.9994 1236448 Maybridge3_003133 N#Cc1ccc(cc1)c2cn3CCSc3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O10 compound treatment 1279128.0 482000.0 1.02 1158765.0 479000.0 1.09 1.4923 0.9995 2076749 Maybridge3_003134 CCCSc1ncccc1C(=O)Nc2c(C)noc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O11 compound treatment 1263704.0 467000.0 0.99 1118150.0 438000.0 1.0 1.4039 1.0 2076750 Maybridge3_003135 Clc1ccc(CSc2nc(NC(=O)c3cccs3)n[nH]2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O12 compound treatment 1515051.0 718000.0 1.52 1177391.0 497000.0 1.13 1.8759 0.9893 2076751 Maybridge3_003136 Clc1cccc(c1)c2n[nH]c(n2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O13 compound treatment 1315448.0 519000.0 1.1 1135287.0 455000.0 1.03 1.509 0.9995 2076752 Maybridge3_003137 Cn1nc(cc1NC(=O)c2cc(Cl)sc2Cl)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O14 compound treatment 1206049.0 409000.0 0.87 1158633.0 479000.0 1.09 1.3826 0.9937 2076753 Maybridge3_003138 Cc1cc(no1)C(=O)Nc2ccc3OCCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O15 compound treatment 1320991.0 524000.0 1.11 1017703.0 338000.0 0.77 1.3283 0.9837 1148356 Maybridge3_003139 O=c1[nH]c(cc(c2cccs2)c1C#N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O16 compound treatment 1325485.0 529000.0 1.12 1066964.0 387000.0 0.88 1.4142 0.9928 2076754 Maybridge3_003140 CC(C)CNC(=O)C1CC(=NO1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O17 compound treatment 1321374.0 524000.0 1.11 1054359.0 374000.0 0.85 1.3878 0.9913 2076755 Maybridge3_003141 Clc1ccccc1CSc2nnc(o2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O18 compound treatment 1280044.0 483000.0 1.02 1076160.0 396000.0 0.9 1.3609 0.9979 2076756 Maybridge3_003142 Cc1cc(nc2oc3c(=O)[nH]cnc3c12)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O19 compound treatment 1274268.0 477000.0 1.01 1160099.0 480000.0 1.09 1.4872 0.9993 2076757 Maybridge3_003143 Oc1ccccc1C(=O)NC(=O)c2cc(oc2C(F)(F)F)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O20 compound treatment 1172443.0 376000.0 0.8 1168022.0 488000.0 1.11 1.3473 0.9868 2076758 Maybridge3_003144 C/C(=C\1/CCOC1=O)/Nc2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O21 compound treatment 1295142.0 498000.0 1.06 1142272.0 462000.0 1.05 1.4898 1.0 2076759 Maybridge3_003145 CS(=O)(=O)N(Cc1ccccc1)Cc2ccccc2N3CCC(CC3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O22 compound treatment 1202157.0 405000.0 0.86 1032448.0 352000.0 0.8 1.1739 0.9994 2076760 Maybridge3_003146 CCOc1ncnc2c1sc3nc(C)cc(C)c32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O23 mock treatment 1003670.0 207000.0 0.44 1006125.0 326000.0 0.74 0.834 0.9686 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 O24 mock treatment 470278.0 -327000.0 -0.69 542778.0 -137000.0 -0.31 -0.7104 -0.9353 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P01 compound treatment 404227.0 -393000.0 -0.83 584920.0 -95200.0 -0.22 -0.7417 -0.8623 2076761 Maybridge3_003147 CCOC(=O)c1nn(cc1C#N)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P02 compound treatment 463539.0 -333000.0 -0.71 616965.0 -63200.0 -0.14 -0.6013 -0.8337 1672168 Maybridge3_003148 Cc1c(oc2ccccc2c1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P03 compound treatment 596452.0 -200000.0 -0.42 754258.0 74100.0 0.17 -0.1813 -0.3966 2076762 Maybridge3_003149 CCOc1ncnc2n(Cc3ccccc3Cl)nnc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P04 compound treatment 689022.0 -108000.0 -0.23 765768.0 85600.0 0.19 -0.0241 -0.0801 2076763 Maybridge3_003150 O=C(c1ccccc1)C2(CC2c3ccccc3)C(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P05 compound treatment 734377.0 -62500.0 -0.13 780112.0 100000.0 0.23 0.067 0.2546 2076764 Maybridge3_003151 CN1CCN(CC1)c2ncc(C#N)c(N)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P06 compound treatment 902302.0 105000.0 0.22 822497.0 142000.0 0.32 0.3869 0.9836 2076765 Maybridge3_003152 O=C1CCC2=C(CCCC2)N1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P07 compound treatment 782466.0 -14400.0 -0.03 563101.0 -117000.0 -0.27 -0.2098 -0.7833 2076766 Maybridge3_003153 Clc1ccc(cc1)c2nnc(Sc3ncnc4n(CC=C)c(=S)sc34)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P08 compound treatment 728838.0 -68100.0 -0.14 724247.0 44100.0 0.1 -0.0311 -0.1771 1458196 Maybridge3_003154 OC(c1c[nH]c2ccccc12)c3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P09 compound treatment 733499.0 -63400.0 -0.13 727839.0 47700.0 0.11 -0.0184 -0.1063 2076767 Maybridge3_003155 Nc1nc(Nc2ccc(F)cc2)ncc1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P10 compound treatment 811891.0 15000.0 0.03 730708.0 50600.0 0.11 0.1038 0.8698 2076768 Maybridge3_003156 OCC(O)C(O)C(O)C1Nc2ccccc2S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P11 compound treatment 664626.0 -132000.0 -0.28 670646.0 -9480.0 -0.02 -0.2135 -0.7592 2076769 Maybridge3_003157 CCOC(=O)CSc1nnc2sc3ccccc3n12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P12 compound treatment 706912.0 -90000.0 -0.19 632650.0 -47500.0 -0.11 -0.2112 -0.9636 1022251 Maybridge3_003158 COC(=O)NCc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P13 compound treatment 730289.0 -66600.0 -0.14 648143.0 -32000.0 -0.07 -0.1513 -0.9524 1061573 Maybridge3_003159 Cc1nc2n(ncc2c(=O)o1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P14 compound treatment 887363.0 90400.0 0.19 699856.0 19700.0 0.04 0.1673 0.8496 1162219 Maybridge3_003160 O=S1(=O)CC(CS(=O)(=O)C1CCN2CCOCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P15 compound treatment 1010300.0 213000.0 0.45 724741.0 44600.0 0.1 0.3916 0.8447 2076770 Maybridge3_003161 CCOC(=O)CSc1nc(cn1c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P16 compound treatment 959944.0 163000.0 0.35 704189.0 24100.0 0.05 0.2831 0.809 2076771 Maybridge3_003162 COc1cccc(c1)I(OC(=O)C)OC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P17 compound treatment 852288.0 55400.0 0.12 650604.0 -29500.0 -0.07 0.0355 0.2628 2076772 Maybridge3_003163 Clc1ccc(cc1)c2nnc3sc(=Cc4cccs4)c(=O)n23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P18 compound treatment 839432.0 42500.0 0.09 685907.0 5780.0 0.01 0.073 0.8017 2076773 Maybridge3_003164 CC1(C)C(NC(=O)c2ccco2)C3(C)CCC1C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P19 compound treatment 971802.0 175000.0 0.37 794773.0 115000.0 0.26 0.4465 0.9851 2076774 Maybridge3_003165 Nc1nc(cc(c2ccco2)c1C#N)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P20 compound treatment 924602.0 128000.0 0.27 784149.0 104000.0 0.24 0.3586 0.9977 2076775 Maybridge3_003166 C(=C/c1ccccc1)\C=N\c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P21 compound treatment 816779.0 19900.0 0.04 663936.0 -16200.0 -0.04 0.0037 0.067 2076776 Maybridge3_003167 N#CCc1c2ccccc2c(CC#N)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P22 compound treatment 669868.0 -127000.0 -0.27 527100.0 -153000.0 -0.35 -0.4365 -0.992 2076777 Maybridge3_003168 CS(=O)(=O)c1ccc(C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P23 mock treatment 547539.0 -249000.0 -0.53 509929.0 -170000.0 -0.39 -0.6474 -0.9882 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1439 P24 mock treatment 445398.0 -352000.0 -0.75 464099.0 -216000.0 -0.49 -0.8742 -0.9795 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A01 compound treatment 380709.0 -363000.0 -0.77 463247.0 -320000.0 -0.73 -1.0587 -0.9996 2077234 Maybridge3_003873 N/C(=N/O)/c1nccnc1Sc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A02 compound treatment 486869.0 -257000.0 -0.55 483250.0 -300000.0 -0.68 -0.8674 -0.9939 2077235 Maybridge3_003874 CSC(C)c1ccn(n1)S(=O)(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A03 compound treatment 438725.0 -305000.0 -0.65 423431.0 -360000.0 -0.82 -1.0357 -0.9933 1138417 Maybridge3_003875 Cc1onc(c1C(=O)Nc2cccc3nsnc23)c4ccccc4Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A04 compound treatment 481535.0 -262000.0 -0.56 472840.0 -310000.0 -0.71 -0.8921 -0.9931 2077236 Maybridge3_003876 N/C(=N\O)/c1nccnc1Oc2cccc(c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A05 compound treatment 485274.0 -259000.0 -0.55 576897.0 -206000.0 -0.47 -0.7192 -0.9969 1656884 Maybridge3_003877 Cn1nc(cc1NC(=O)C2COc3ccccc3O2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A06 compound treatment 519798.0 -224000.0 -0.48 550755.0 -232000.0 -0.53 -0.7095 -0.9986 2077237 Maybridge3_003878 COC(=O)CSc1cc(nc2cc(nn12)C(C)(C)C)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A07 compound treatment 529752.0 -214000.0 -0.45 575708.0 -207000.0 -0.47 -0.6545 -0.9998 2077238 Maybridge3_003879 Cn1cnc(c1)S(=O)(=O)N=S(=O)(C)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A08 compound treatment 520541.0 -223000.0 -0.47 447761.0 -335000.0 -0.76 -0.874 -0.9738 1063968 Maybridge3_003880 C(c1ccccc1)n2ccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A09 compound treatment 557093.0 -187000.0 -0.4 610047.0 -173000.0 -0.39 -0.5583 -1.0 1573915 Maybridge3_003881 O=C(Oc1ccccc1)c2csc(n2)C3COc4ccccc4O3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A10 compound treatment 496772.0 -247000.0 -0.52 596346.0 -187000.0 -0.42 -0.6707 -0.9945 2077239 Maybridge3_003882 O=S(=O)(C1CS(=O)(=O)c2ccccc12)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A11 compound treatment 478748.0 -265000.0 -0.56 621390.0 -162000.0 -0.37 -0.6575 -0.9788 1240503 Maybridge3_003883 O=C(Oc1ccccc1)c2ccc3OCCc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A12 compound treatment 499129.0 -245000.0 -0.52 433942.0 -349000.0 -0.79 -0.9283 -0.9788 2077240 Maybridge3_003884 COc1cc(nc2ccc(C)c(N)c12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A13 compound treatment 482868.0 -261000.0 -0.55 615406.0 -168000.0 -0.38 -0.6609 -0.9834 2077241 Maybridge3_003885 Cn1c(SCc2ccc(Br)cc2F)nnc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A14 compound treatment 574712.0 -169000.0 -0.36 656696.0 -126000.0 -0.29 -0.4569 -0.9939 2077242 Maybridge3_003886 COc1cc(nc2ccc(C)c(NC(=O)c3ccccc3)c12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A15 compound treatment 523475.0 -220000.0 -0.47 495470.0 -288000.0 -0.65 -0.7929 -0.9865 1654432 Maybridge3_003887 Brc1cc2CCOc2c(c1)C(=O)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A16 compound treatment 495947.0 -248000.0 -0.53 502366.0 -281000.0 -0.64 -0.8231 -0.9954 2077243 Maybridge3_003888 C/S(=N\S(=O)(=O)c1cccc2nsnc12)/c3ncccc3C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A17 compound treatment 491091.0 -253000.0 -0.54 590829.0 -192000.0 -0.44 -0.6881 -0.9949 1415267 Maybridge3_003889 N#CCOc1ccc2nonc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A18 compound treatment 467615.0 -276000.0 -0.59 502190.0 -281000.0 -0.64 -0.8658 -0.9991 2077244 Maybridge3_003890 O=S(=O)(/C(=C/NC1CCN(Cc2ccccc2)CC1)/C#N)c3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A19 compound treatment 488241.0 -256000.0 -0.54 602558.0 -181000.0 -0.41 -0.6735 -0.9906 1645474 Maybridge3_003891 Clc1ccc(C(=O)Oc2ccc3c(=O)ccoc3c2)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A20 compound treatment 476237.0 -268000.0 -0.57 515026.0 -268000.0 -0.61 -0.8323 -0.9994 1580603 Maybridge3_003892 O=S(=O)(CCN1CCC(CC1)n2cccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A21 compound treatment 498997.0 -245000.0 -0.52 529368.0 -254000.0 -0.58 -0.7751 -0.9986 2077245 Maybridge3_003893 COC(=O)c1scc2c(OC)cc(nc12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A22 compound treatment 473593.0 -270000.0 -0.57 473335.0 -310000.0 -0.7 -0.9032 -0.9948 1330270 Maybridge3_003894 O=C(Nc1ccc(cc1)N2CCC(CC2)n3cccc3)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A23 mock treatment 470277.0 -274000.0 -0.58 392509.0 -391000.0 -0.89 -1.0382 -0.9787 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 A24 mock treatment 416985.0 -327000.0 -0.69 379455.0 -404000.0 -0.92 -1.139 -0.9904 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B01 compound treatment 445268.0 -299000.0 -0.63 397388.0 -386000.0 -0.88 -1.0678 -0.9872 2077246 Maybridge3_003895 CSc1nn(cc1C(=O)Sc2cccs2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B02 compound treatment 736521.0 -7450.0 -0.02 909407.0 126000.0 0.29 0.1919 0.6672 1229384 Maybridge3_003896 COc1c(I)cc(Cl)c2cccnc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B03 compound treatment 934327.0 190000.0 0.4 1093077.0 310000.0 0.7 0.7837 0.965 1462132 Maybridge3_003897 CCOC(=O)c1c(SC)nc2c(Cl)cccc2c1N(C)CCO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B04 compound treatment 995983.0 252000.0 0.53 1162017.0 379000.0 0.86 0.987 0.9736 2077247 Maybridge3_003898 FC(F)(F)c1cccc(NC(=O)c2ccc3ncccc3c2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B05 compound treatment 947785.0 204000.0 0.43 1111999.0 329000.0 0.75 0.8343 0.966 2077248 Maybridge3_003899 Cc1ccc2nc(cc(N3CCN(CCS(=O)(=O)c4ccc(Cl)cc4)CC3)c2c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B06 compound treatment 1067228.0 323000.0 0.69 1194436.0 411000.0 0.94 1.1459 0.9883 2077249 Maybridge3_003900 FC(F)(F)c1c2CCCc2nc3cc(nn13)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B07 compound treatment 935095.0 191000.0 0.41 931796.0 149000.0 0.34 0.5256 0.996 1557957 Maybridge3_003901 O=C(Oc1ccccc1)c2c(nnc3ccccc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B08 compound treatment 989111.0 245000.0 0.52 974990.0 192000.0 0.44 0.676 0.9962 2077250 Maybridge3_003902 CCOC(=O)N1CCN(CC1)c2cc(nc3ccccc23)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B09 compound treatment 1023430.0 279000.0 0.59 1015586.0 233000.0 0.53 0.7927 0.9984 2077251 Maybridge3_003903 COc1ccc(cc1OC)S(=O)(=O)N(CCC#N)Cc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B10 compound treatment 1006494.0 263000.0 0.56 1187606.0 405000.0 0.92 1.0439 0.971 2077252 Maybridge3_003904 FC(F)(F)c1cc(N2CCN(CCOC(=O)C3CC3)CC2)c4cccc(Cl)c4n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B11 compound treatment 1015249.0 271000.0 0.58 1139208.0 356000.0 0.81 0.9792 0.986 2077253 Maybridge3_003905 Oc1ccnc2ccc(OC(F)(F)F)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B12 compound treatment 1080736.0 337000.0 0.71 1228379.0 445000.0 1.01 1.2207 0.9854 1672604 Maybridge3_003906 O=C(N1CCOCC1)c2ccc3snnc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B13 compound treatment 994022.0 250000.0 0.53 962126.0 179000.0 0.41 0.6627 0.9915 2077254 Maybridge3_003907 OC1(CC(=NO1)c2cccs2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B14 compound treatment 965582.0 222000.0 0.47 1023427.0 240000.0 0.55 0.7186 0.9972 2077255 Maybridge3_003908 Cc1ccc2nc(cc(N3CCC(CC3)C(=O)O)c2c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B15 compound treatment 999885.0 256000.0 0.54 944769.0 162000.0 0.37 0.6436 0.982 2077256 Maybridge3_003909 COc1ccc(cc1OC2CCCC2)/C(=N/O)/N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B16 compound treatment 881894.0 138000.0 0.29 918117.0 135000.0 0.31 0.4239 0.9997 1012681 Maybridge3_003910 OC(=O)CSc1ccnc2cc(Cl)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B17 compound treatment 961549.0 218000.0 0.46 961880.0 179000.0 0.41 0.6136 0.998 2077257 Maybridge3_003911 Fc1cccc(OC(=O)c2ccc3nonc3c2)c1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B18 compound treatment 932769.0 189000.0 0.4 949557.0 166000.0 0.38 0.5507 0.9996 2077258 Maybridge3_003912 CN(C(=O)c1cc2c(C)cc(C)cc2[nH]1)c3ccc(F)cc3F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B19 compound treatment 1054962.0 311000.0 0.66 1026831.0 244000.0 0.55 0.8581 0.9963 2077259 Maybridge3_003913 CN(C)S(=O)(=O)c1ccc(s1)c2cc(on2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B20 compound treatment 985770.0 242000.0 0.51 896681.0 114000.0 0.26 0.5451 0.9497 1360569 Maybridge3_003914 CS(=O)(=O)N1CCN(CC1)c2ccnc3cc(Cl)ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B21 compound treatment 897365.0 153000.0 0.33 972818.0 190000.0 0.43 0.535 0.9903 1729595 Maybridge3_003915 O=S(=O)(N1CCN(CC1)c2ccccc2)c3cccc4nsnc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B22 compound treatment 887279.0 143000.0 0.3 870983.0 87900.0 0.2 0.3562 0.9794 2077260 Maybridge3_003916 C/C=C/C(=O)N1CCN(CC1)c2ccnc3cc(Cl)ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B23 mock treatment 730481.0 -13500.0 -0.03 596975.0 -186000.0 -0.42 -0.3194 -0.7532 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 B24 mock treatment 490286.0 -254000.0 -0.54 482207.0 -301000.0 -0.68 -0.864 -0.9929 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C01 compound treatment 462265.0 -282000.0 -0.6 457656.0 -325000.0 -0.74 -0.9454 -0.9944 1646562 Maybridge3_003917 CS(=O)(=NS(=O)(=O)c1cccc2nsnc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C02 compound treatment 736371.0 -7600.0 -0.02 717618.0 -65400.0 -0.15 -0.1166 -0.7791 2077261 Maybridge3_003918 COC(=O)c1csc(c1OC)S(=O)(=O)Nc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C03 compound treatment 1035322.0 291000.0 0.62 897791.0 115000.0 0.26 0.6212 0.9265 2077262 Maybridge3_003919 FC(F)(F)c1ccc(SCC(=O)Nc2cccc3nsnc23)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C04 compound treatment 1106230.0 362000.0 0.77 870849.0 87800.0 0.2 0.6842 0.8622 1615428 Maybridge3_003920 COC(=O)c1csc(c1OC)S(=O)(=O)N2CCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C05 compound treatment 1053050.0 309000.0 0.66 970086.0 187000.0 0.43 0.764 0.9781 2077263 Maybridge3_003921 N/C(=N\O)/c1ccc2nonc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C06 compound treatment 1239654.0 496000.0 1.05 1014123.0 231000.0 0.53 1.1145 0.9487 2077264 Maybridge3_003922 COC(=O)c1scc2c(Oc3ccccc3)cc(nc12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C07 compound treatment 1074717.0 331000.0 0.7 1050011.0 267000.0 0.61 0.925 0.9974 1678019 Maybridge3_003923 O=C(Sc1ccccn1)c2csc(n2)C3COc4ccccc4O3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C08 compound treatment 1235458.0 491000.0 1.04 989893.0 207000.0 0.47 1.0693 0.9354 2077265 Maybridge3_003924 Cn1c(SCc2nccn2Cc3ccc(Cl)cc3)nnc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C09 compound treatment 1131149.0 387000.0 0.82 1116526.0 333000.0 0.76 1.1165 0.9992 1626824 Maybridge3_003925 CCOC(=O)c1sc(nc1C)C2COc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C10 compound treatment 1236568.0 493000.0 1.04 1179704.0 397000.0 0.9 1.3761 0.9973 1922402 Maybridge3_003926 COC(=O)c1ccc(C#CC(C)(C)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C11 compound treatment 1208044.0 464000.0 0.98 1098518.0 315000.0 0.72 1.2028 0.9879 2077266 Maybridge3_003927 C(Sc1cccs1)c2ccc3nonc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C12 compound treatment 1261089.0 517000.0 1.1 1122755.0 340000.0 0.77 1.3213 0.9853 2077267 Maybridge3_003928 Clc1ccc(CSc2nccnc2C#N)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C13 compound treatment 1177669.0 434000.0 0.92 964044.0 181000.0 0.41 0.9411 0.9343 2077268 Maybridge3_003929 Fc1cc(Br)ccc1CS(=O)(=O)c2ccccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C14 compound treatment 986001.0 242000.0 0.51 1126851.0 344000.0 0.78 0.9155 0.9792 2077269 Maybridge3_003930 CCOC(=O)c1cncc(C#CCOC(=O)c2ccc(Cl)cc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C15 compound treatment 1042111.0 298000.0 0.63 1136463.0 353000.0 0.8 1.0151 0.9929 1249394 Maybridge3_003931 NC(=O)c1cc(Br)cc2CCOc21 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C16 compound treatment 1025035.0 281000.0 0.6 1118077.0 335000.0 0.76 0.9599 0.9926 2077270 Maybridge3_003932 NC(=O)C1CCN(CC1)c2cc(ccn2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C17 compound treatment 975042.0 231000.0 0.49 812839.0 29800.0 0.07 0.3943 0.7972 2077271 Maybridge3_003933 CC(C)(C)c1csc(n1)c2ccc3nonc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C18 compound treatment 1072598.0 329000.0 0.7 804237.0 21200.0 0.05 0.5267 0.7542 1266206 Maybridge3_003934 OCc1sccc1Oc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C19 compound treatment 1140556.0 397000.0 0.84 1209973.0 427000.0 0.97 1.2808 0.9974 2077272 Maybridge3_003935 CSc1nn2c(cc(nc2c1C(=O)O)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C20 compound treatment 1253296.0 509000.0 1.08 1221467.0 438000.0 1.0 1.4683 0.9992 2077273 Maybridge3_003936 FC(F)(F)c1nnc(SC(=O)c2ccc(C#Cc3ccccc3)o2)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C21 compound treatment 954367.0 210000.0 0.45 1132671.0 350000.0 0.79 0.8774 0.9627 2077274 Maybridge3_003937 FC(F)(F)c1cc(Oc2ccccc2)c3cccc(C#N)c3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C22 compound treatment 1025252.0 281000.0 0.6 1148895.0 366000.0 0.83 1.0098 0.9867 1735700 Maybridge3_003938 CCOC(=O)c1c(O)c2cc(Cl)ccc2nc1SC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C23 mock treatment 842071.0 98100.0 0.21 883049.0 100000.0 0.23 0.3078 0.999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 C24 mock treatment 487914.0 -256000.0 -0.54 469377.0 -314000.0 -0.71 -0.8881 -0.9909 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D01 compound treatment 463923.0 -280000.0 -0.59 347164.0 -436000.0 -0.99 -1.1206 -0.97 2077275 Maybridge3_003939 CSc1nn(cc1C(=O)Sc2ccccn2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D02 compound treatment 748801.0 4830.0 0.01 856219.0 73200.0 0.17 0.1248 0.7492 1585459 Maybridge3_003940 Cc1occc1c2cc(N)n(n2)c3cccc(Cl)c3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D03 compound treatment 885606.0 142000.0 0.3 885592.0 103000.0 0.23 0.3771 0.9922 1370289 Maybridge3_003941 OC(=O)c1cncc(C#CCC2CCCCC2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D04 compound treatment 1047573.0 304000.0 0.64 897858.0 115000.0 0.26 0.6397 0.921 1614929 Maybridge3_003942 O=C(NCCc1ccccc1)c2ccc3ncccc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D05 compound treatment 1106708.0 363000.0 0.77 999902.0 217000.0 0.49 0.8924 0.9769 2077276 Maybridge3_003943 O=C(Nc1ccccc1)OCC#Cc2ccc(C#N)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D06 compound treatment 1148242.0 404000.0 0.86 1094136.0 311000.0 0.71 1.1061 0.9954 2077277 Maybridge3_003944 Nc1nc(cc(n1)C(F)(F)F)c2nccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D07 compound treatment 1080391.0 336000.0 0.71 995698.0 213000.0 0.48 0.8461 0.9821 1671972 Maybridge3_003945 COc1cc(NC(=O)c2c(nnc3ccccc23)c4ccccc4)cc(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D08 compound treatment 1105874.0 362000.0 0.77 907127.0 124000.0 0.28 0.742 0.9077 2077278 Maybridge3_003946 FC(F)(F)c1cc(nc2ccnn12)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D09 compound treatment 1167877.0 424000.0 0.9 1093690.0 311000.0 0.71 1.1348 0.9929 1510085 Maybridge3_003947 COc1ccc(cc1OC)S(=O)(=O)NC2CCc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D10 compound treatment 1135416.0 391000.0 0.83 1061719.0 279000.0 0.63 1.0348 0.9911 1241394 Maybridge3_003948 COC(=O)c1ccc2n(nnc2c1)C3CCN(Cc4ccccc4)CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D11 compound treatment 1100602.0 357000.0 0.76 1174344.0 391000.0 0.89 1.1636 0.9967 1127976 Maybridge3_003949 O=S(=O)(N(CCC#N)Cc1cccs1)c2cccc3nsnc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D12 compound treatment 1261197.0 517000.0 1.1 1390704.0 608000.0 1.38 1.7522 0.9935 2077279 Maybridge3_003950 C=CCn1c(SCC(=O)NCc2ccccc2)nnc1c3ccc4ncccc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D13 compound treatment 1125224.0 381000.0 0.81 1053707.0 271000.0 0.62 1.0066 0.9909 1480094 Maybridge3_003951 Clc1cccc2c(ccnc12)N3CCC(CC3)n4cccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D14 compound treatment 1136802.0 393000.0 0.83 1182710.0 400000.0 0.91 1.2314 0.9991 2077280 Maybridge3_003952 Cn1c(CNC(=O)c2ccccc2)nnc1SCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D15 compound treatment 1135191.0 391000.0 0.83 1169752.0 387000.0 0.88 1.2081 0.9996 1558253 Maybridge3_003953 Fc1ccc(NC(=O)c2ccc3nonc3c2)c(F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D16 compound treatment 1169252.0 425000.0 0.9 1223982.0 441000.0 1.0 1.3463 0.9986 1120418 Maybridge3_003954 CSc1nc2ccc(NC(=O)c3ccc4snnc4c3)cc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D17 compound treatment 1078609.0 335000.0 0.71 1273543.0 490000.0 1.12 1.2901 0.9762 1459416 Maybridge3_003955 O=C(N1CCN(CC1)c2ccccc2)c3ccc4nonc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D18 compound treatment 1194121.0 450000.0 0.95 1077747.0 295000.0 0.67 1.1485 0.985 1585700 Maybridge3_003956 COCC(C)NC(=O)c1cc2c(C)cc(C)cc2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D19 compound treatment 1154242.0 410000.0 0.87 1255902.0 473000.0 1.08 1.3752 0.9945 1708839 Maybridge3_003957 N#Cc1nccnc1N2CCN(Cc3ccccc3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D20 compound treatment 1127142.0 383000.0 0.81 1278430.0 495000.0 1.13 1.3708 0.9871 1732100 Maybridge3_003958 Clc1ccc2c(ccnc2c1)N3CCN(CC3)C(=O)C4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D21 compound treatment 1099018.0 355000.0 0.75 1115082.0 332000.0 0.75 1.066 1.0 1392947 Maybridge3_003959 O=S(=O)(NCCc1c[nH]c2ccccc12)c3cccc4nsnc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D22 compound treatment 987894.0 244000.0 0.52 1071749.0 289000.0 0.66 0.8297 0.993 1736799 Maybridge3_003960 CN(C)c1ccc(cc1)C(=O)N2CCN(CC2)c3ccnc4cc(Cl)ccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D23 mock treatment 620843.0 -123000.0 -0.26 925381.0 142000.0 0.32 0.0442 0.1064 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 D24 mock treatment 535579.0 -208000.0 -0.44 469172.0 -314000.0 -0.71 -0.817 -0.9734 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E01 compound treatment 422082.0 -322000.0 -0.68 590108.0 -193000.0 -0.44 -0.7927 -0.9772 2077281 Maybridge3_003961 Clc1ccc(cc1)C(=O)N2CCSC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E02 compound treatment 819343.0 75400.0 0.16 844411.0 61300.0 0.14 0.2116 0.9977 2077282 Maybridge3_003962 CSc1nn(cc1c2noc(n2)c3ccc(Cl)cc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E03 compound treatment 1018471.0 275000.0 0.58 946889.0 164000.0 0.37 0.6749 0.9768 2077283 Maybridge3_003963 Clc1ccc(NS(=O)(=O)c2cccc3nonc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E04 compound treatment 1144183.0 400000.0 0.85 1024313.0 241000.0 0.55 0.9878 0.9777 2077284 Maybridge3_003964 FC(F)(F)c1cccc(Oc2nccnc2c3noc(n3)c4cccs4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E05 compound treatment 1081624.0 338000.0 0.72 1032841.0 250000.0 0.57 0.9077 0.9934 1319212 Maybridge3_003965 CC(C)C1Oc2c(cccc2NC1=O)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E06 compound treatment 1169270.0 425000.0 0.9 1225234.0 442000.0 1.01 1.3484 0.9985 2077285 Maybridge3_003966 COc1cc(nc2ccc(C#CCO)cc12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E07 compound treatment 1200560.0 457000.0 0.97 1124508.0 341000.0 0.78 1.2334 0.994 2077286 Maybridge3_003967 Oc1cc(nc2[nH]nc(c3cccs3)c12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E08 compound treatment 1223482.0 480000.0 1.02 1301417.0 518000.0 1.18 1.5521 0.9973 2077287 Maybridge3_003968 C(#Cc1ccccc1)c2ccc(s2)c3cc[nH]n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E09 compound treatment 1143183.0 399000.0 0.85 1313477.0 530000.0 1.21 1.4511 0.985 2077288 Maybridge3_003969 CSc1nn2c(cc(nc2c1C#N)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E10 compound treatment 1320261.0 576000.0 1.22 1171230.0 388000.0 0.88 1.4879 0.9873 2077289 Maybridge3_003970 FC(F)(F)c1ccc(nc1)N2CCC(CC2)C(=O)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E11 compound treatment 1344573.0 601000.0 1.27 1146779.0 364000.0 0.83 1.485 0.9782 2077290 Maybridge3_003971 FC(F)(F)c1ccc(SCc2ccc3nonc3c2)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E12 compound treatment 1265361.0 521000.0 1.11 1632617.0 850000.0 1.93 2.1474 0.9649 2077291 Maybridge3_003972 FC(F)(F)c1ccc2SCC(=O)N(Cc3ccccc3)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E13 compound treatment 1671532.0 928000.0 1.97 1798870.0 1020000.0 2.31 3.0235 0.9968 1332456 Maybridge3_003973 Cc1csc(n1)c2sc3ccccc3c2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E14 compound treatment 1341837.0 598000.0 1.27 1437112.0 654000.0 1.49 1.9477 0.9968 1258662 Maybridge3_003974 CN(C)CC#Cc1ccc(s1)c2cc[nH]n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E15 compound treatment 1156469.0 412000.0 0.87 1402147.0 619000.0 1.41 1.6136 0.9738 2077292 Maybridge3_003975 COc1c(C)cnc(CO)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E16 compound treatment 1164061.0 420000.0 0.89 1304810.0 522000.0 1.19 1.4685 0.99 2077293 Maybridge3_003976 O=C(Nc1ccc2COC(=O)c2c1)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E17 compound treatment 1199784.0 456000.0 0.97 1333495.0 550000.0 1.25 1.5682 0.9918 1718090 Maybridge3_003977 N#Cc1ccc(cc1)c2csc(COc3ccc4nonc4c3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E18 compound treatment 1119983.0 376000.0 0.8 1368605.0 586000.0 1.33 1.505 0.9699 2077294 Maybridge3_003978 Brc1ccc(s1)c2ccn(n2)S(=O)(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E19 compound treatment 1289972.0 546000.0 1.16 1182048.0 399000.0 0.91 1.4599 0.9927 2077295 Maybridge3_003979 CC(C)(C)c1cc2nc(cc(C#N)n2n1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E20 compound treatment 1208994.0 465000.0 0.99 1109720.0 327000.0 0.74 1.2222 0.9902 1507720 Maybridge3_003980 O=C(Nc1ccccc1)c2ccc(C#Cc3ccccc3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E21 compound treatment 1130812.0 387000.0 0.82 1213868.0 431000.0 0.98 1.2725 0.9961 1264652 Maybridge3_003981 Cc1ccc(cc1)C(=O)Nc2ccc3CS(=O)(=O)Cc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E22 compound treatment 1072206.0 328000.0 0.7 1082863.0 300000.0 0.68 0.974 0.9999 1101325 Maybridge3_003982 OC1CN(C1)C(c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E23 mock treatment 785732.0 41800.0 0.09 1019084.0 236000.0 0.54 0.442 0.8128 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 E24 mock treatment 573800.0 -170000.0 -0.36 648562.0 -135000.0 -0.31 -0.4713 -0.9966 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F01 compound treatment 565096.0 -179000.0 -0.38 858802.0 75700.0 0.17 -0.1464 -0.3515 2077296 Maybridge3_003983 CSc1nn(cc1C(=O)Oc2ccc(Cl)cc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F02 compound treatment 901381.0 157000.0 0.33 936770.0 154000.0 0.35 0.4831 0.9997 2077297 Maybridge3_003984 CC(=O)Nc1c(nn2c(C)cc(nc12)C(F)(F)F)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F03 compound treatment 948057.0 204000.0 0.43 968064.0 185000.0 0.42 0.6033 0.9999 2077298 Maybridge3_003985 FC(F)(F)c1cc(N2CCN(CC2)S(=O)(=O)c3ccccc3)c4ccccc4n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F04 compound treatment 1080174.0 336000.0 0.71 1028077.0 245000.0 0.56 0.8979 0.9926 1662303 Maybridge3_003986 COc1ccc(OC(=O)c2ccc3ncccc3c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F05 compound treatment 1117567.0 374000.0 0.79 1050823.0 268000.0 0.61 0.9905 0.9916 1634093 Maybridge3_003987 O=C(CSc1ccccc1)N2CCC(CC2)n3cccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F06 compound treatment 1297058.0 553000.0 1.17 1186917.0 404000.0 0.92 1.4783 0.9927 2077299 Maybridge3_003988 Nc1nc(cc(n1)C(F)(F)F)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F07 compound treatment 1224803.0 481000.0 1.02 1059708.0 277000.0 0.63 1.1655 0.9731 1420243 Maybridge3_003989 Cc1ccc(NC(=O)c2c(nnc3ccccc23)c4ccccc4)cc1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F08 compound treatment 1294749.0 551000.0 1.17 1022179.0 239000.0 0.54 1.21 0.9395 2077300 Maybridge3_003990 FC(F)(F)c1ccn(n1)c2cc(=O)c3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F09 compound treatment 1228042.0 484000.0 1.03 1166859.0 384000.0 0.87 1.3426 0.9967 2077301 Maybridge3_003991 CSc1scc(NC(=O)c2ccc(C)cc2)c1S(=O)(=O)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F10 compound treatment 1397185.0 653000.0 1.38 1247228.0 464000.0 1.06 1.7254 0.991 2077302 Maybridge3_003992 Cn1c(CNC(=O)OC(C)(C)C)nnc1SCc2c(F)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F11 compound treatment 1433498.0 690000.0 1.46 1382485.0 599000.0 1.36 1.9973 0.9994 2077303 Maybridge3_003993 CCOC(=O)c1sc(SC)c(c1N)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F12 compound treatment 1390499.0 647000.0 1.37 1420000.0 637000.0 1.45 1.9931 0.9996 2077304 Maybridge3_003994 CC(C)NC(=O)CSc1nnc(c2ccc3ncccc3c2)n1CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F13 compound treatment 1233443.0 489000.0 1.04 1343375.0 560000.0 1.27 1.6345 0.9948 2077305 Maybridge3_003995 CCOC(=O)Cc1cc(=O)n2nc(cc2[nH]1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F14 compound treatment 1455160.0 711000.0 1.51 1261887.0 479000.0 1.09 1.8359 0.9872 1423418 Maybridge3_003996 COC(=O)CSc1ccnc2cc(Cl)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F15 compound treatment 1267266.0 523000.0 1.11 998488.0 215000.0 0.49 1.1308 0.9325 2077306 Maybridge3_003997 FC(F)(F)c1cccc(NC(=O)c2ccc3nonc3c2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F16 compound treatment 1434524.0 691000.0 1.46 1190040.0 407000.0 0.93 1.6894 0.9755 2077307 Maybridge3_003998 O=C(Nc1ccc2CS(=O)(=O)Cc2c1)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F17 compound treatment 1333932.0 590000.0 1.25 1268538.0 485000.0 1.1 1.6648 0.9981 2077308 Maybridge3_003999 FC(F)(F)c1cc(n[nH]1)c2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F18 compound treatment 1247430.0 503000.0 1.07 1103148.0 320000.0 0.73 1.2693 0.9826 2077309 Maybridge3_004000 Cc1cc(C)c2cc([nH]c2c1)C(=O)NCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F19 compound treatment 1259519.0 516000.0 1.09 1118218.0 335000.0 0.76 1.3116 0.9845 1523206 Maybridge3_004001 N#Cc1nccnc1N2CCN(CC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F20 compound treatment 1250161.0 506000.0 1.07 1012280.0 229000.0 0.52 1.1273 0.945 1149229 Maybridge3_004002 CCS(=O)(=O)N1CCN(CC1)c2ccnc3cc(Cl)ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F21 compound treatment 1165714.0 422000.0 0.89 1097473.0 314000.0 0.71 1.1377 0.9939 2077310 Maybridge3_004003 CN(C)S(=O)(=O)Nc1ccc(C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F22 compound treatment 1068638.0 325000.0 0.69 935804.0 153000.0 0.35 0.7322 0.9498 1200296 Maybridge3_004004 Clc1ccc2c(ccnc2c1)N3CCN(CC3)C(=O)Cc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F23 mock treatment 962027.0 218000.0 0.46 926947.0 144000.0 0.33 0.5582 0.9857 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 F24 mock treatment 631413.0 -113000.0 -0.24 529953.0 -253000.0 -0.58 -0.5756 -0.924 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G01 compound treatment 601001.0 -143000.0 -0.3 848932.0 65900.0 0.15 -0.1084 -0.3207 2077311 Maybridge3_004005 CSc1nnc(SCCS(=O)(=O)c2ccc(Cl)cc2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G02 compound treatment 1105730.0 362000.0 0.77 1216103.0 433000.0 0.98 1.2385 0.9924 1162460 Maybridge3_004006 OCC#Cc1ccc(s1)c2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G03 compound treatment 1117225.0 373000.0 0.79 1103675.0 321000.0 0.73 1.0749 0.9992 1636969 Maybridge3_004007 CS(=N)(=O)c1ccc(Oc2cccc(F)c2C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G04 compound treatment 1076406.0 332000.0 0.7 999234.0 216000.0 0.49 0.8459 0.9845 2077312 Maybridge3_004008 COC(=O)CSc1cc(nc2c(scc12)C(=O)OC)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G05 compound treatment 1102828.0 359000.0 0.76 982895.0 200000.0 0.45 0.8592 0.9696 1130330 Maybridge3_004009 CCOC(=O)CN1C(=O)C(Oc2c(cccc12)C(C)C)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G06 compound treatment 1237546.0 494000.0 1.05 1105722.0 323000.0 0.73 1.2586 0.9849 1729930 Maybridge3_004010 CCOC(=O)c1cn(Cc2ccccc2)c3cc(C)nn3c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G07 compound treatment 1213714.0 470000.0 1.0 1127057.0 344000.0 0.78 1.2572 0.9929 2077313 Maybridge3_004011 CCOC(=O)c1csc(n1)c2ccc3nonc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G08 compound treatment 1147884.0 404000.0 0.86 1036069.0 253000.0 0.58 1.0122 0.9813 2077314 Maybridge3_004012 FC(F)(F)C1CCN(CCS(=O)(=O)c2ccccc2)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G09 compound treatment 1072124.0 328000.0 0.7 1143351.0 360000.0 0.82 1.0711 0.9967 1726778 Maybridge3_004013 Cc1nc(sc1C(=O)O)C2COc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G10 compound treatment 1549021.0 805000.0 1.71 1179994.0 397000.0 0.9 1.8449 0.9556 2077315 Maybridge3_004014 CSc1ncc2c(O)ncnc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G11 compound treatment 1524016.0 780000.0 1.65 1268208.0 485000.0 1.1 1.9493 0.9806 2077316 Maybridge3_004015 O=S(Cc1ccc2nonc2c1)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G12 compound treatment 1127023.0 383000.0 0.81 1413998.0 631000.0 1.43 1.5885 0.9637 1382187 Maybridge3_004016 CCOC(=O)c1cncc(C#CC(C)(C)O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G13 compound treatment 1204720.0 461000.0 0.98 1264552.0 481000.0 1.09 1.4647 0.9984 1638255 Maybridge3_004017 Cc1ccc(cc1)C(=O)NCC2COc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G14 compound treatment 1157014.0 413000.0 0.88 1413896.0 631000.0 1.43 1.6333 0.972 1146518 Maybridge3_004018 NC(=O)CCOC1CCN(CC1)C(c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G15 compound treatment 1418084.0 674000.0 1.43 1419844.0 637000.0 1.45 2.0342 1.0 1131426 Maybridge3_004019 CC(C)(C)NC(=O)c1cc(Br)cc2CCOc21 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G16 compound treatment 1250092.0 506000.0 1.07 694604.0 -88500.0 -0.2 0.6165 0.5647 1374712 Maybridge3_004020 O=C(Nc1ccc2COC(=O)c2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G17 compound treatment 1149383.0 405000.0 0.86 1290883.0 508000.0 1.15 1.4241 0.9894 2077317 Maybridge3_004021 Cc1cc(nc2c(Cl)c(nn12)C3CC3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G18 compound treatment 1256557.0 513000.0 1.09 1502684.0 720000.0 1.64 1.9253 0.9802 1374157 Maybridge3_004022 O=C(N1CCC(CC1)n2cccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G19 compound treatment 1285425.0 541000.0 1.15 1322397.0 539000.0 1.23 1.6787 0.9995 2077318 Maybridge3_004023 Oc1cc(nc2c(OC(F)(F)F)cccc12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G20 compound treatment 1168247.0 424000.0 0.9 1194804.0 412000.0 0.94 1.2979 0.9998 1689779 Maybridge3_004024 O=C(N1CCOCC1)c2ccc(C#Cc3ccccc3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G21 compound treatment 1091388.0 347000.0 0.74 1084537.0 301000.0 0.69 1.0054 0.9994 1702398 Maybridge3_004025 COc1ccc(cc1)S(=O)(=O)Nc2ccc3CS(=O)(=O)Cc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G22 compound treatment 1076470.0 332000.0 0.7 1086219.0 303000.0 0.69 0.9858 0.9999 1391261 Maybridge3_004026 CCOC(=O)c1c(O)c2cccc(Cl)c2nc1SC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G23 mock treatment 1038706.0 295000.0 0.62 1088604.0 306000.0 0.69 0.933 0.9986 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 G24 mock treatment 664388.0 -79600.0 -0.17 678508.0 -105000.0 -0.24 -0.2874 -0.9859 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H01 compound treatment 633938.0 -110000.0 -0.23 879559.0 96500.0 0.22 -0.0098 -0.0307 2077319 Maybridge3_004027 COc1ccc(OC(=O)c2cn(nc2SC)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H02 compound treatment 1185618.0 442000.0 0.94 1438437.0 655000.0 1.49 1.7156 0.9749 1405433 Maybridge3_004028 CC(C)N1CCC(CC1)n2nnc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H03 compound treatment 1099976.0 356000.0 0.75 1255891.0 473000.0 1.07 1.2938 0.985 2077320 Maybridge3_004029 FC(F)(F)c1cc(N2CCN(CC2)C(=O)c3ccccc3)c4ccccc4n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H04 compound treatment 1051002.0 307000.0 0.65 1344666.0 562000.0 1.28 1.3631 0.9511 1181065 Maybridge3_004030 O=C(N1CCN(CC1)c2ccccc2)c3ccc4ncccc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H05 compound treatment 1261456.0 517000.0 1.1 1115204.0 332000.0 0.76 1.3097 0.9834 2077321 Maybridge3_004031 O=C(OCC#Cc1ccc(C#N)cc1)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H06 compound treatment 1532921.0 789000.0 1.67 1309568.0 527000.0 1.2 2.0291 0.9865 2077322 Maybridge3_004032 Nc1nc(c2CCc3ccccc3-c2n1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H07 compound treatment 1476815.0 733000.0 1.55 1119075.0 336000.0 0.76 1.6387 0.9466 2077323 Maybridge3_004033 Cn1c(CSCC(=O)Nc2ccccc2)nnc1SCC(=O)c3ccc(F)c(F)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H08 compound treatment 1459870.0 716000.0 1.52 1270354.0 487000.0 1.11 1.8565 0.988 2077324 Maybridge3_004034 FC(F)(F)c1cc(nc2cc(nn12)c3cccs3)c4nccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H09 compound treatment 1332311.0 588000.0 1.25 1344149.0 561000.0 1.28 1.784 0.9999 1237588 Maybridge3_004035 CSc1scc(NS(=O)(=O)c2ccc(Cl)cc2)c1S(=O)(=O)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H10 compound treatment 1510810.0 767000.0 1.63 1678286.0 895000.0 2.04 2.5887 0.9938 1211183 Maybridge3_004036 COc1cc(NC(=O)c2ccc3snnc3c2)cc(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H11 compound treatment 1090727.0 347000.0 0.74 1357548.0 574000.0 1.31 1.4434 0.963 2077325 Maybridge3_004037 Clc1ccc(cc1)S(=O)(=O)n2ncc(C#N)c2C3CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H12 compound treatment 1750434.0 1010000.0 2.13 1682538.0 899000.0 2.04 2.9548 0.9998 1725990 Maybridge3_004038 O=C(NCc1ccco1)c2ccc3snnc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H13 compound treatment 1502888.0 759000.0 1.61 1201536.0 418000.0 0.95 1.8104 0.9686 1261573 Maybridge3_004039 Clc1ccc(cc1)S(=O)(=O)N(CCC(=O)Nc2ccccc2)Cc3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H14 compound treatment 1536226.0 792000.0 1.68 1385515.0 602000.0 1.37 2.1561 0.9949 2077326 Maybridge3_004040 COC(=O)c1ccc(Cn2cnc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H15 compound treatment 1565198.0 821000.0 1.74 1604307.0 821000.0 1.87 2.5513 0.9994 2077327 Maybridge3_004041 COc1ccc(NC(=O)c2ccc3nonc3c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H16 compound treatment 1513924.0 770000.0 1.63 1427693.0 645000.0 1.47 2.1905 0.9986 2077328 Maybridge3_004042 CC(=O)N1CCC(CC1)c2nc(no2)c3ccc(cc3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H17 compound treatment 1536976.0 793000.0 1.68 1538000.0 755000.0 1.72 2.4024 0.9999 2077329 Maybridge3_004043 COc1ccc(cc1OC2CCCC2)c3noc(n3)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H18 compound treatment 1524244.0 780000.0 1.65 1324550.0 541000.0 1.23 2.0402 0.9894 1331976 Maybridge3_004044 CCc1ccc2[nH]c(cc2c1)C(=O)N(C)c3ccc(F)cc3F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H19 compound treatment 1396973.0 653000.0 1.38 1467362.0 684000.0 1.56 2.079 0.9983 1661316 Maybridge3_004045 Fc1ccc(cc1)S(=O)(=O)CCN2CCN(CC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H20 compound treatment 1347443.0 603000.0 1.28 1074971.0 292000.0 0.66 1.3739 0.9533 1700688 Maybridge3_004046 CC(C)S(=O)(=O)N1CCN(CC1)c2ccnc3cc(Cl)ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H21 compound treatment 1210525.0 467000.0 0.99 1264767.0 482000.0 1.1 1.4738 0.9987 1535026 Maybridge3_004047 CCOC(=O)Nc1cncc(Br)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H22 compound treatment 1176468.0 432000.0 0.92 1132720.0 350000.0 0.79 1.2104 0.9975 1199932 Maybridge3_004048 Cc1cc(Nc2ccccc2)c3ccccc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H23 mock treatment 1113638.0 370000.0 0.78 1040169.0 257000.0 0.58 0.9675 0.9896 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 H24 mock treatment 901183.0 157000.0 0.33 817113.0 34000.0 0.08 0.2904 0.8487 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I01 compound treatment 724557.0 -19400.0 -0.04 933350.0 150000.0 0.34 0.2125 0.6175 2077330 Maybridge3_004049 O/N=C/c1ccc2OCCc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I02 compound treatment 973477.0 230000.0 0.49 1393268.0 610000.0 1.39 1.325 0.9013 2077331 Maybridge3_004050 CSc1nn(cc1c2noc(n2)c3cccs3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I03 compound treatment 1344896.0 601000.0 1.27 1246243.0 463000.0 1.05 1.6454 0.9955 2077332 Maybridge3_004051 Cc1occc1C(=O)C(=C2SCCCCS2)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I04 compound treatment 1273714.0 530000.0 1.12 1289512.0 506000.0 1.15 1.6083 0.9999 2077333 Maybridge3_004052 O/N=C/C(=O)Nc1ccccc1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I05 compound treatment 1333768.0 590000.0 1.25 1358763.0 576000.0 1.31 1.8096 0.9997 2077334 Maybridge3_004053 CCOC(=O)c1csc(n1)C2COc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I06 compound treatment 1461133.0 717000.0 1.52 1475734.0 693000.0 1.57 2.1886 0.9998 2077335 Maybridge3_004054 COC(=O)c1sccc1Oc2cc(nc3c(scc23)C(=O)OC)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I07 compound treatment 1292528.0 549000.0 1.16 1535292.0 752000.0 1.71 2.0316 0.9823 1167446 Maybridge3_004055 O=C(Nc1ccccc1)c2csc(n2)C3COc4ccccc4O3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I08 compound treatment 1614921.0 871000.0 1.85 1295840.0 513000.0 1.17 2.1299 0.9754 2077336 Maybridge3_004056 CC(C)(C)c1cc2nc(cc(SCCO)n2n1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I09 compound treatment 1631276.0 887000.0 1.88 1609154.0 826000.0 1.88 2.6582 1.0 2077337 Maybridge3_004057 CC1(C)Oc2ccc(cc2C=C1)/C(=N/O)/N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I10 compound treatment 1465564.0 722000.0 1.53 1328304.0 545000.0 1.24 1.9582 0.9946 2077338 Maybridge3_004058 FC(F)(F)c1ccc(nc1)N2CCC(CC2)C(=O)Oc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I11 compound treatment 1534814.0 791000.0 1.68 1328237.0 545000.0 1.24 2.0619 0.989 2077339 Maybridge3_004059 C(SCc1ccc2nonc2c1)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I12 compound treatment 1227745.0 484000.0 1.03 1371797.0 589000.0 1.34 1.6717 0.9914 2077340 Maybridge3_004060 O=S(=O)(/C(=C/c1c[nH]cn1)/C#N)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I13 compound treatment 1171602.0 428000.0 0.91 1268186.0 485000.0 1.1 1.4209 0.9953 1742782 Maybridge3_004061 CC(C)(C)C(=O)NCC1COc2ccccc2O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I14 compound treatment 1443421.0 699000.0 1.48 1577348.0 794000.0 1.81 2.3254 0.9952 1581992 Maybridge3_004062 COc1ccc(OC(=O)c2cncc(C#Cc3ccccc3)c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I15 compound treatment 1400227.0 656000.0 1.39 1500473.0 717000.0 1.63 2.1371 0.9969 2077341 Maybridge3_004063 Clc1ccc(CSc2nc3CSCc3c(=O)[nH]2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I16 compound treatment 1614227.0 870000.0 1.84 1374116.0 591000.0 1.34 2.2547 0.9879 2077342 Maybridge3_004064 O=C1OCc2ccc(NS(=O)(=O)c3ccccc3)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I17 compound treatment 1277844.0 534000.0 1.13 1345729.0 563000.0 1.28 1.7049 0.9981 2077343 Maybridge3_004065 Oc1cc(nc2ccc(Br)cc12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I18 compound treatment 1520869.0 777000.0 1.65 1628955.0 846000.0 1.92 2.5245 0.997 2077344 Maybridge3_004066 Cn1c(SCCS(=O)(=O)c2ccc(F)cc2)nnc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I19 compound treatment 1520542.0 777000.0 1.65 1587604.0 805000.0 1.83 2.4575 0.9986 2077345 Maybridge3_004067 CC(C)Oc1cc(nc2ccc(C)cc12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I20 compound treatment 1473237.0 729000.0 1.55 1365010.0 582000.0 1.32 2.0288 0.997 1522065 Maybridge3_004068 O=C(N1CCCCC1)c2ccc(C#Cc3ccccc3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I21 compound treatment 1274865.0 531000.0 1.13 1223480.0 440000.0 1.0 1.5039 0.9983 1485285 Maybridge3_004069 NC(=O)C1CCN(CCS(=O)(=O)c2ccccc2)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I22 compound treatment 1238665.0 495000.0 1.05 1342321.0 559000.0 1.27 1.6406 0.9954 2077346 Maybridge3_004070 O=C(Nc1ccccc1)c2ncc[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I23 mock treatment 1267217.0 523000.0 1.11 1257335.0 474000.0 1.08 1.5468 0.9999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 I24 mock treatment 854130.0 110000.0 0.23 659688.0 -123000.0 -0.28 -0.0332 -0.091 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J01 compound treatment 1198704.0 455000.0 0.96 1000006.0 217000.0 0.49 1.0304 0.9516 1583673 Maybridge3_004071 CSc1nn(cc1C(=O)N2CCCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J02 compound treatment 1130499.0 387000.0 0.82 1334499.0 551000.0 1.25 1.4659 0.9788 1456490 Maybridge3_004072 OC(=O)C1CN(C1)C(c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J03 compound treatment 1147494.0 404000.0 0.86 1439621.0 657000.0 1.49 1.6604 0.9651 2077347 Maybridge3_004073 C(#Cc1ccc(cc1)c2ccn[nH]2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J04 compound treatment 1031114.0 287000.0 0.61 1450680.0 668000.0 1.52 1.5037 0.9195 1541332 Maybridge3_004074 O=C(N1CCOCC1)c2ccc3ncccc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J05 compound treatment 1161043.0 417000.0 0.88 1388382.0 605000.0 1.38 1.5983 0.9771 2077348 Maybridge3_004075 CCOC(=O)Cc1c(C(=O)OCC)c(C)cn1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J06 compound treatment 1432660.0 689000.0 1.46 1484160.0 701000.0 1.59 2.1595 0.999 1477926 Maybridge3_004076 Cn1c(SCC(=O)NCc2ccccc2)nnc1c3ccc4ncccc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J07 compound treatment 1384388.0 640000.0 1.36 1346731.0 564000.0 1.28 1.8662 0.9996 2077349 Maybridge3_004077 C/C(=N\O)/c1ccccc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J08 compound treatment 1077936.0 334000.0 0.71 1401219.0 618000.0 1.41 1.4944 0.9496 2077350 Maybridge3_004078 OCCN1CCN(CC1)c2cc(nc3ccccc23)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J09 compound treatment 1659826.0 916000.0 1.94 1246988.0 464000.0 1.05 2.1187 0.9589 2077351 Maybridge3_004079 COc1ccc(/C=N/O)cc1OC2CCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J10 compound treatment 1402742.0 659000.0 1.4 1419836.0 637000.0 1.45 2.0112 0.9998 2077352 Maybridge3_004080 COC(=O)c1ccc(CSc2nnc(c3ccc4ncccc4c3)n2C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J11 compound treatment 1144124.0 400000.0 0.85 1681343.0 898000.0 2.04 2.044 0.9243 1118471 Maybridge3_004081 Clc1ccc(cc1)C(=O)n2ncc(C#N)c2C3CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J12 compound treatment 1578945.0 835000.0 1.77 1721984.0 939000.0 2.13 2.7611 0.9957 2077353 Maybridge3_004082 OC1CCN(CC1)c2cc(nc3cc(Cl)cc(Cl)c23)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J13 compound treatment 1225764.0 482000.0 1.02 1632584.0 850000.0 1.93 2.0879 0.9556 1435746 Maybridge3_004083 CCOC(=O)Cc1cc(=O)n2nc(C)cc2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J14 compound treatment 1596259.0 852000.0 1.81 1779178.0 996000.0 2.26 2.879 0.9937 2077354 Maybridge3_004084 CC(C)n1c(nc2cc(ccc12)C(=O)NCc3ccncc3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J15 compound treatment 1486284.0 742000.0 1.57 1714746.0 932000.0 2.12 2.6106 0.9893 1545156 Maybridge3_004085 Clc1ccc(NC(=O)c2ccc3nonc3c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J16 compound treatment 1471602.0 728000.0 1.54 1463534.0 680000.0 1.55 2.1847 1.0 2077355 Maybridge3_004086 C1CCN(CC1)c2noc(n2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J17 compound treatment 1397144.0 653000.0 1.38 1616512.0 833000.0 1.89 2.319 0.9881 2077356 Maybridge3_004087 Cn1c(SCc2ccccc2)nnc1c3ccc4nonc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J18 compound treatment 1658473.0 915000.0 1.94 1426150.0 643000.0 1.46 2.4047 0.9903 2077357 Maybridge3_004088 CN(C(=O)c1cc2c(C)cc(C)cc2[nH]1)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J19 compound treatment 1627836.0 884000.0 1.87 1360073.0 577000.0 1.31 2.2526 0.9848 2077358 Maybridge3_004089 FC(F)(F)c1cc(N2CCCC2)c3cccc(Cl)c3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J20 compound treatment 1254522.0 511000.0 1.08 1340808.0 558000.0 1.27 1.662 0.9969 1547868 Maybridge3_004090 Clc1ccc2c(Nc3ccc4OCOc4c3)ccnc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J21 compound treatment 1266066.0 522000.0 1.11 1144683.0 362000.0 0.82 1.364 0.9893 1436487 Maybridge3_004091 O=S(=O)(N1CCc2ccccc12)c3cccc4nsnc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J22 compound treatment 1010903.0 267000.0 0.57 1058964.0 276000.0 0.63 0.8437 0.9987 1712208 Maybridge3_004092 Cc1cc(Nc2ccc(C)c(F)c2)c3ccccc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J23 mock treatment 1014962.0 271000.0 0.57 1255938.0 473000.0 1.08 1.1664 0.9569 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 J24 mock treatment 596272.0 -148000.0 -0.31 646114.0 -137000.0 -0.31 -0.4416 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K01 compound treatment 862981.0 119000.0 0.25 839374.0 56300.0 0.13 0.2689 0.9505 2077359 Maybridge3_004093 N/C(=N/O)/C1COc2ccccc2O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K02 compound treatment 1008617.0 265000.0 0.56 1180186.0 397000.0 0.9 1.0351 0.9738 2077360 Maybridge3_004094 CS(=O)(=O)NCCSc1cc(nc2ccccc12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K03 compound treatment 1095161.0 351000.0 0.74 1150848.0 368000.0 0.84 1.1177 0.9983 1286819 Maybridge3_004095 O=C(Sc1cccs1)C2COc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K04 compound treatment 1001145.0 257000.0 0.55 1171884.0 389000.0 0.88 1.0106 0.973 2077361 Maybridge3_004096 COC(=O)c1scc2c(Sc3nccn3C)cc(nc12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K05 compound treatment 1032455.0 288000.0 0.61 1254364.0 471000.0 1.07 1.1901 0.9646 1368806 Maybridge3_004097 Clc1ccccc1c2nc(no2)c3ccc4nonc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K06 compound treatment 1343723.0 600000.0 1.27 1384116.0 601000.0 1.37 1.8653 0.9994 1522513 Maybridge3_004098 Cc1[nH]c2ccccc2c1SCc3nnc(SCC(=O)Nc4ccccc4)n3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K07 compound treatment 1413811.0 670000.0 1.42 1233314.0 450000.0 1.02 1.728 0.9871 1339013 Maybridge3_004099 CN(C)C(=O)c1csc(n1)C2COc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K08 compound treatment 1306339.0 562000.0 1.19 1298368.0 515000.0 1.17 1.6714 1.0 2077362 Maybridge3_004100 CCOC(=O)c1ccc(OCC#Cc2ccc(cn2)C(F)(F)F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K09 compound treatment 1272531.0 529000.0 1.12 1261238.0 478000.0 1.09 1.5611 0.9999 1146145 Maybridge3_004101 O=C(Nc1ccccc1)c2ccc3OCCc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K10 compound treatment 1356689.0 613000.0 1.3 1290780.0 508000.0 1.15 1.7347 0.9983 1555938 Maybridge3_004102 O=S1(=O)CC(N2CCCCC2)c3ccccc31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K11 compound treatment 1574147.0 830000.0 1.76 1454787.0 672000.0 1.53 2.3244 0.9975 2077363 Maybridge3_004103 CN(C(=O)c1ccc2OCCc2c1)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K12 compound treatment 943235.0 199000.0 0.42 1326761.0 544000.0 1.24 1.1728 0.8978 2077364 Maybridge3_004104 CC(C)S(=O)(=O)/C(=C/c1c[nH]cn1)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K13 compound treatment 1217794.0 474000.0 1.0 1473812.0 691000.0 1.57 1.8208 0.9767 2077365 Maybridge3_004105 Nc1ccccc1SCc2ccc3nonc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K14 compound treatment 1501075.0 757000.0 1.61 1450527.0 667000.0 1.52 2.208 0.9996 1460370 Maybridge3_004106 C(#Cc1cncc(c1)c2nc(no2)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K15 compound treatment 1263226.0 519000.0 1.1 1360710.0 578000.0 1.31 1.707 0.9961 2077366 Maybridge3_004107 Cn1cc(cc1/C=C(\C#N)/S(=O)(=O)c2cccs2)C(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K16 compound treatment 1461590.0 718000.0 1.52 1440186.0 657000.0 1.49 2.1322 1.0 2077367 Maybridge3_004108 Cn1c(SCC(=O)Nc2ccccc2)nnc1c3cncc(C#Cc4ccccc4)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K17 compound treatment 1438297.0 694000.0 1.47 1681041.0 898000.0 2.04 2.4844 0.9871 2077368 Maybridge3_004109 Cc1cc(C)n2nc(c(Cl)c2n1)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K18 compound treatment 1424315.0 680000.0 1.44 1515713.0 733000.0 1.67 2.1977 0.9974 2077369 Maybridge3_004110 FC(F)(F)c1ccc(nc1)N2CCC(CC2)n3cccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K19 compound treatment 1446116.0 702000.0 1.49 1572708.0 790000.0 1.8 2.322 0.9957 2077370 Maybridge3_004111 Cn1c(Sc2cccs2)nc(C#N)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K20 compound treatment 1401597.0 658000.0 1.39 1359438.0 576000.0 1.31 1.9124 0.9995 1197251 Maybridge3_004112 O=C(N1CCCC1)c2ccc(C#Cc3ccccc3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K21 compound treatment 1320221.0 576000.0 1.22 1197994.0 415000.0 0.94 1.5309 0.9918 2077371 Maybridge3_004113 OC(=O)CSc1cc(nc2ccccc12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K22 compound treatment 1095336.0 351000.0 0.74 1136680.0 354000.0 0.8 1.0952 0.9993 1060162 Maybridge3_004114 O=C1CC2CCCC(C1)N2Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K23 mock treatment 893743.0 150000.0 0.32 1149626.0 367000.0 0.83 0.8138 0.9125 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 K24 mock treatment 503050.0 -241000.0 -0.51 652759.0 -130000.0 -0.3 -0.5706 -0.9664 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L01 compound treatment 533447.0 -211000.0 -0.45 834790.0 51700.0 0.12 -0.2324 -0.5036 2077372 Maybridge3_004115 COC(=O)c1c(C)[nH]c(C)c1/C=C(\C#N)/S(=O)(=O)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L02 compound treatment 1184368.0 440000.0 0.93 1115071.0 332000.0 0.75 1.1939 0.9944 2077373 Maybridge3_004116 COC(=O)c1ccccc1NC(=O)/C=N/O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L03 compound treatment 926112.0 182000.0 0.39 1304615.0 522000.0 1.19 1.1115 0.8913 1421413 Maybridge3_004117 COC(=O)C(Cc1csc2ccc(Cl)cc12)NC(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L04 compound treatment 1174358.0 430000.0 0.91 1353598.0 571000.0 1.3 1.5624 0.9852 1389033 Maybridge3_004118 COC(=O)c1sccc1NC(=O)c2ccc3ncccc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L05 compound treatment 1082916.0 339000.0 0.72 1313302.0 530000.0 1.21 1.3605 0.9694 2077374 Maybridge3_004119 Cn1c(CSCC(=O)Nc2ccccc2)nnc1SCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L06 compound treatment 1434244.0 690000.0 1.46 1491820.0 709000.0 1.61 2.1742 0.9988 2077375 Maybridge3_004120 COC(=O)c1ccc2n(nnc2c1)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L07 compound treatment 1290554.0 547000.0 1.16 1282711.0 500000.0 1.14 1.6226 1.0 2077376 Maybridge3_004121 Nc1cc(n[nH]1)c2cccc(c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L08 compound treatment 1211782.0 468000.0 0.99 1325593.0 543000.0 1.23 1.5735 0.9942 1207721 Maybridge3_004122 Cn1nnnc1SCC(=O)NC2Cc3ccccc3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L09 compound treatment 1293612.0 550000.0 1.17 1227980.0 445000.0 1.01 1.5392 0.9975 2077377 Maybridge3_004123 C/C(=N\O)/c1ccc(C#Cc2ccccc2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L10 compound treatment 1259690.0 516000.0 1.09 1548341.0 765000.0 1.74 2.0034 0.9749 2077378 Maybridge3_004124 CSc1nnc(c2ccc3ncccc3c2)n1CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L11 compound treatment 1412484.0 669000.0 1.42 1435963.0 653000.0 1.48 2.0518 0.9997 2077379 Maybridge3_004125 O=C(c1cccs1)n2ncc(C#N)c2C3CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L12 compound treatment 1581733.0 838000.0 1.78 1529814.0 747000.0 1.7 2.4563 0.9997 2077380 Maybridge3_004126 FC(F)(F)c1cc(N2CCC(=O)CC2)c3c(Cl)cc(Cl)cc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L13 compound treatment 1476894.0 733000.0 1.55 1899958.0 1120000.0 2.54 2.8942 0.9722 1174104 Maybridge3_004127 CCOC(=O)Cc1cc(=O)n2nc(cc2[nH]1)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L14 compound treatment 1667548.0 924000.0 1.96 1697259.0 914000.0 2.08 2.8542 0.9996 2077381 Maybridge3_004128 CC(C)n1c(nc2cc(ccc12)C(=O)N3CCCCC3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L15 compound treatment 1384171.0 640000.0 1.36 1296629.0 514000.0 1.17 1.7853 0.9972 1556737 Maybridge3_004129 Clc1ccc(OC(=O)c2ccc3nonc3c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L16 compound treatment 1423294.0 679000.0 1.44 1441851.0 659000.0 1.5 2.0774 0.9998 1225885 Maybridge3_004130 COc1ccc2c(CC(=O)O)coc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L17 compound treatment 1269676.0 526000.0 1.11 1293011.0 510000.0 1.16 1.6079 0.9998 1128713 Maybridge3_004131 CSc1nc(N)nc(n1)C2COc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L18 compound treatment 1273021.0 529000.0 1.12 1548672.0 766000.0 1.74 2.0239 0.9774 1364620 Maybridge3_004132 O=C(NCc1ccc(s1)S(=O)(=O)NCCc2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L19 compound treatment 1302550.0 559000.0 1.18 1358432.0 575000.0 1.31 1.7623 0.9988 1329219 Maybridge3_004133 Clc1ccc(cc1)S(=O)(=O)CCN2CCN(Cc3ccccc3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L20 compound treatment 1204408.0 460000.0 0.98 1260730.0 478000.0 1.09 1.4581 0.9986 1549522 Maybridge3_004134 Cc1ccc(Nc2ccnc3cc(Cl)ccc23)cc1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L21 compound treatment 1165327.0 421000.0 0.89 1117202.0 334000.0 0.76 1.1688 0.9968 1288040 Maybridge3_004135 N#CC1(CCN(Cc2ccccc2)CC1)NCCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L22 compound treatment 1116657.0 373000.0 0.79 1339132.0 556000.0 1.26 1.4526 0.9744 1682067 Maybridge3_004136 O=C(NCc1ccc(s1)S(=O)(=O)NC2CCCCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L23 mock treatment 988519.0 245000.0 0.52 1196096.0 413000.0 0.94 1.0306 0.9608 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 L24 mock treatment 540559.0 -203000.0 -0.43 671678.0 -111000.0 -0.25 -0.484 -0.9678 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M01 compound treatment 516748.0 -227000.0 -0.48 733173.0 -49900.0 -0.11 -0.4208 -0.8504 2077382 Maybridge3_004137 CSC(=C(C#N)C(=O)c1ccoc1C)SC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M02 compound treatment 1161846.0 418000.0 0.89 1123905.0 341000.0 0.77 1.1744 0.9978 2077383 Maybridge3_004138 O=C(OCC#Cc1ccc(s1)c2ccccn2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M03 compound treatment 1087187.0 343000.0 0.73 1308812.0 526000.0 1.2 1.3597 0.9717 1134608 Maybridge3_004139 O=C(Nc1cc(n[nH]1)c2ccccc2)C3COc4ccccc4O3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M04 compound treatment 1179188.0 435000.0 0.92 1307796.0 525000.0 1.19 1.496 0.9919 2077384 Maybridge3_004140 FC(F)(F)c1ccc(Oc2ccc(Br)cc2)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M05 compound treatment 1068046.0 324000.0 0.69 1280364.0 497000.0 1.13 1.2853 0.9715 1601097 Maybridge3_004141 COc1ccc(NS(=O)(=O)c2cn(C)cn2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M06 compound treatment 1257089.0 513000.0 1.09 1299057.0 516000.0 1.17 1.5987 0.9993 1644493 Maybridge3_004142 Clc1ccc(Cn2ccnc2COC(=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M07 compound treatment 1061170.0 317000.0 0.67 1160526.0 377000.0 0.86 1.0823 0.9927 1286518 Maybridge3_004143 O=C(NCc1ccco1)c2csc(n2)C3COc4ccccc4O3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M08 compound treatment 1169509.0 426000.0 0.9 1400027.0 617000.0 1.4 1.6298 0.9772 2077385 Maybridge3_004144 CC(C)(O)C#Cc1ccc(CO)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M09 compound treatment 1191655.0 448000.0 0.95 1210864.0 428000.0 0.97 1.3588 0.9999 2077386 Maybridge3_004145 CNC(=O)c1ccc2OCCc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M10 compound treatment 1263012.0 519000.0 1.1 1412302.0 629000.0 1.43 1.7896 0.9916 1677679 Maybridge3_004146 Clc1ccc(s1)S(=O)(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M11 compound treatment 1165497.0 422000.0 0.89 1238101.0 455000.0 1.03 1.3634 0.9973 1430746 Maybridge3_004147 CN(C)CC1COc2ccccc2C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M12 compound treatment 1326093.0 582000.0 1.23 1257319.0 474000.0 1.08 1.6351 0.9977 2077387 Maybridge3_004148 Clc1ccc(cc1)S(=O)(=O)/C(=C/c2c[nH]cn2)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M13 compound treatment 1206515.0 463000.0 0.98 1421820.0 639000.0 1.45 1.7203 0.9817 1167106 Maybridge3_004149 Brc1cc2CCOc2c(c1)C(=O)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M14 compound treatment 1383644.0 640000.0 1.36 1295004.0 512000.0 1.16 1.7819 0.9971 2077388 Maybridge3_004150 CN(C)CC#Cc1cncc(C#N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M15 compound treatment 1179619.0 436000.0 0.92 1190744.0 408000.0 0.93 1.3085 1.0 1276171 Maybridge3_004151 N#Cc1ccc(OCc2ccc3nonc3c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M16 compound treatment 1192032.0 448000.0 0.95 1231096.0 448000.0 1.02 1.3919 0.9994 2077389 Maybridge3_004152 O=C(Sc1cccs1)c2cncc(C#Cc3ccccc3)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M17 compound treatment 1169503.0 426000.0 0.9 1329771.0 547000.0 1.24 1.5168 0.9876 2077390 Maybridge3_004153 O=C(Sc1ccccc1)c2ccc3ncsc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M18 compound treatment 1319017.0 575000.0 1.22 1271730.0 489000.0 1.11 1.6476 0.9989 2077391 Maybridge3_004154 Fc1ccc(cc1)S(=O)(=O)CCSc2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M19 compound treatment 1280501.0 537000.0 1.14 1276771.0 494000.0 1.12 1.598 1.0 2077392 Maybridge3_004155 Cn1c(CC2Sc3ccccc3NC2=O)nnc1SCC(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M20 compound treatment 1265227.0 521000.0 1.11 1243064.0 460000.0 1.05 1.5209 0.9996 2077393 Maybridge3_004156 COC(=O)CSCC1=CS(=O)(=O)c2ccc(Cl)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M21 compound treatment 1054026.0 310000.0 0.66 1180996.0 398000.0 0.9 1.1045 0.9877 1387055 Maybridge3_004157 Cc1ncn2cc([nH]c(=O)c12)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M22 compound treatment 1126478.0 383000.0 0.81 1202336.0 419000.0 0.95 1.2474 0.9968 1682804 Maybridge3_004158 ON=C1CC2CCCC(C1)N2Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M23 mock treatment 1005866.0 262000.0 0.56 1023128.0 240000.0 0.55 0.7785 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 M24 mock treatment 564543.0 -179000.0 -0.38 615305.0 -168000.0 -0.38 -0.5387 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N01 compound treatment 961972.0 218000.0 0.46 806788.0 23700.0 0.05 0.3649 0.7843 2077394 Maybridge3_004159 CS(=O)(=O)N1CCN(CC1)c2cc(nc3ccccc23)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N02 compound treatment 1027048.0 283000.0 0.6 1278758.0 496000.0 1.13 1.2212 0.9565 1276474 Maybridge3_004160 O=C(Nc1ccccc1)c2ccc3ncccc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N03 compound treatment 1171435.0 427000.0 0.91 1436385.0 653000.0 1.49 1.6911 0.9719 2077395 Maybridge3_004161 CC(=O)n1ccc(n1)c2ccc(C#Cc3ccccc3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N04 compound treatment 1178046.0 434000.0 0.92 1503372.0 720000.0 1.64 1.8087 0.9628 1515408 Maybridge3_004162 Clc1ccc(cc1)C(=O)N2CCC(CC2)n3nnc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N05 compound treatment 1178934.0 435000.0 0.92 1529187.0 746000.0 1.7 1.8515 0.959 2077396 Maybridge3_004163 c1ccc(cc1)c2cc3ccccc3nn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N06 compound treatment 910481.0 167000.0 0.35 1535230.0 752000.0 1.71 1.4588 0.8355 1203539 Maybridge3_004164 COc1ccc(cc1OC)C(=O)NC2Cc3ccccc3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N07 compound treatment 1141164.0 397000.0 0.84 1438495.0 655000.0 1.49 1.6491 0.9635 1329343 Maybridge3_004165 CC(=O)NC(=O)c1cnn(c1N)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N08 compound treatment 931528.0 188000.0 0.4 1254970.0 472000.0 1.07 1.0398 0.9088 1485969 Maybridge3_004166 Cn1ccnc1SCC(=O)NC2Cc3ccccc3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N09 compound treatment 1024076.0 280000.0 0.59 1311779.0 529000.0 1.2 1.2699 0.9472 2077397 Maybridge3_004167 COc1ccc(cc1OC)S(=O)(=O)N(CCC#N)C2CCc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N10 compound treatment 1104759.0 361000.0 0.76 1541372.0 758000.0 1.72 1.7599 0.9331 2077398 Maybridge3_004168 Cn1c(SCC#N)nnc1c2ccc3ncccc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N11 compound treatment 1157484.0 414000.0 0.88 1345596.0 563000.0 1.28 1.5242 0.983 1461212 Maybridge3_004169 CSc1sc(C(=O)O)c(C)c1C(C)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N12 compound treatment 1037790.0 294000.0 0.62 1602595.0 820000.0 1.86 1.758 0.8948 2077399 Maybridge3_004170 Fc1ccc2nc(cc(N3CCOCC3)c2c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N13 compound treatment 1028588.0 285000.0 0.6 1385981.0 603000.0 1.37 1.3959 0.9321 2077400 Maybridge3_004171 FC(F)(F)c1cc(nc2cc(nn12)c3ccccc3)c4ccccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N14 compound treatment 1130487.0 387000.0 0.82 1330964.0 548000.0 1.25 1.4602 0.9794 2077401 Maybridge3_004172 CC(C)n1c(nc2cc(ccc12)C(=O)N3CCC(O)CC3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N15 compound treatment 1004236.0 260000.0 0.55 1286498.0 503000.0 1.14 1.1995 0.944 1710980 Maybridge3_004173 COc1ccc(OC(=O)c2ccc3nonc3c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N16 compound treatment 1068782.0 325000.0 0.69 1347269.0 564000.0 1.28 1.3939 0.9575 2077402 Maybridge3_004174 CCc1ccc2[nH]c(cc2c1)C(=O)NCCN3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N17 compound treatment 1035418.0 291000.0 0.62 1504590.0 722000.0 1.64 1.5968 0.911 1579669 Maybridge3_004175 Nc1nc(ncc1C#N)C2COc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N18 compound treatment 1122009.0 378000.0 0.8 1387186.0 604000.0 1.37 1.5379 0.9671 1418287 Maybridge3_004176 Clc1ccc2c(Nc3ccccc3)ccnc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N19 compound treatment 1197745.0 454000.0 0.96 1600551.0 817000.0 1.86 1.9944 0.953 1622980 Maybridge3_004177 Brc1ccc(s1)S(=O)(=O)N2CCN(CC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N20 compound treatment 1341580.0 598000.0 1.27 1389008.0 606000.0 1.38 1.87 0.9991 1739946 Maybridge3_004178 Clc1ccc2c(ccnc2c1)N3CCN(CC3)C(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N21 compound treatment 1321065.0 577000.0 1.22 1284103.0 501000.0 1.14 1.6706 0.9994 2077403 Maybridge3_004179 Cc1cc(Nc2cc(nc3c(Cl)cccc23)C(F)(F)F)on1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N22 compound treatment 1154473.0 411000.0 0.87 1274112.0 491000.0 1.12 1.4048 0.9924 1374568 Maybridge3_004180 CCC(=O)N1CCN(CC1)c2ccnc3cc(Cl)ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N23 mock treatment 1044783.0 301000.0 0.64 1189163.0 406000.0 0.92 1.1038 0.9837 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 N24 mock treatment 568016.0 -176000.0 -0.37 706341.0 -76700.0 -0.17 -0.3871 -0.9401 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O01 compound treatment 412822.0 -331000.0 -0.7 693405.0 -89700.0 -0.2 -0.6405 -0.8762 2077404 Maybridge3_004181 O=S(=O)(Nc1cccc2nsnc12)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O02 compound treatment 1042979.0 299000.0 0.63 941462.0 158000.0 0.36 0.7029 0.9641 2077405 Maybridge3_004182 Clc1cccc(NC(=O)OCC#Cc2ccc(s2)c3ccccn3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O03 compound treatment 1188546.0 445000.0 0.94 1242893.0 460000.0 1.05 1.4057 0.9987 1586200 Maybridge3_004183 CC(C)(C)c1cc(NC(=O)C2COc3ccccc3O2)[nH]n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O04 compound treatment 1299682.0 556000.0 1.18 1360246.0 577000.0 1.31 1.7609 0.9986 2077406 Maybridge3_004184 COC(=O)c1scc2c(cc(nc12)C(F)(F)F)N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O05 compound treatment 1342728.0 599000.0 1.27 1206648.0 424000.0 0.96 1.5785 0.9907 1200852 Maybridge3_004185 OC(=O)c1csc(n1)C2COc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O06 compound treatment 1421170.0 677000.0 1.44 1177123.0 394000.0 0.9 1.6487 0.9742 1252194 Maybridge3_004186 Clc1ccc(Cn2ccnc2COC(=O)Nc3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O07 compound treatment 1283428.0 539000.0 1.14 1276009.0 493000.0 1.12 1.6011 0.9999 1603073 Maybridge3_004187 O=C(SCc1ccco1)c2csc(n2)C3COc4ccccc4O3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O08 compound treatment 1287492.0 544000.0 1.15 1264397.0 481000.0 1.09 1.5886 0.9997 1365631 Maybridge3_004188 O=S1(=O)CC(Sc2ccccc2)c3ccccc31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O09 compound treatment 1465160.0 721000.0 1.53 1228346.0 445000.0 1.01 1.7969 0.98 1337081 Maybridge3_004189 CC(C)(C)NC(=O)c1ccc2OCCc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O10 compound treatment 1441876.0 698000.0 1.48 1206347.0 423000.0 0.96 1.7267 0.9783 1676570 Maybridge3_004190 CC(C)(C)OC(=O)N1CCN(CCNC(=O)c2ccccc2)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O11 compound treatment 97063.0 -647000.0 -1.37 92808.0 -690000.0 -1.57 -2.0794 -0.9977 2077407 Maybridge3_004191 CSc1ncc(c2nnc(SCc3ccccc3)n2C)n1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O12 compound treatment 1449948.0 706000.0 1.5 1155897.0 373000.0 0.85 1.6577 0.9638 2077408 Maybridge3_004192 CCOC(=O)c1cncc(C#CCOC(=O)Nc2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O13 compound treatment 1098805.0 355000.0 0.75 1012040.0 229000.0 0.52 0.9 0.9838 2077409 Maybridge3_004193 CN(C)C(=O)c1cc(Br)cc2CCOc21 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O14 compound treatment 1141068.0 397000.0 0.84 1114856.0 332000.0 0.75 1.1287 0.9985 2077410 Maybridge3_004194 C/S(=N\S(=O)(=O)c1cccc2nsnc12)/c3ccc(cn3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O15 compound treatment 1294828.0 551000.0 1.17 1194178.0 411000.0 0.93 1.4867 0.9939 1347374 Maybridge3_004195 Cc1c(ncn1Cc2ccc(Cl)cc2)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O16 compound treatment 1440494.0 697000.0 1.48 1100790.0 318000.0 0.72 1.5549 0.9459 2077411 Maybridge3_004196 Clc1ccc(cc1)S(=O)(=O)/C(=C/NC2CCN(Cc3ccccc3)CC2)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O17 compound treatment 1405063.0 661000.0 1.4 1153773.0 371000.0 0.84 1.587 0.9704 2077412 Maybridge3_004197 CN(C)C(=O)c1ccc2ncsc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O18 compound treatment 1270303.0 526000.0 1.12 1074410.0 291000.0 0.66 1.2574 0.969 1389063 Maybridge3_004198 NC(=O)C1CCN(CCO)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O19 compound treatment 1562037.0 818000.0 1.73 1174358.0 391000.0 0.89 1.8554 0.9519 2077413 Maybridge3_004199 CN(C)CCOc1cc(nc2ccc(C)cc12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O20 compound treatment 1429712.0 686000.0 1.45 1190897.0 408000.0 0.93 1.6836 0.9764 2077414 Maybridge3_004200 Clc1ccc2c(c1)C(=CS2(=O)=O)CSc3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O21 compound treatment 1521494.0 778000.0 1.65 1316697.0 534000.0 1.21 2.0234 0.9886 2077415 Maybridge3_004201 CC(C)NC(=O)CSc1nnc(CSc2cc(nc3ccccc23)C(F)(F)F)n1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O22 compound treatment 1282515.0 539000.0 1.14 1165221.0 382000.0 0.87 1.4217 0.9909 2077416 Maybridge3_004202 CSc1nn(cc1C(=O)Nc2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O23 mock treatment 1139218.0 395000.0 0.84 1094435.0 311000.0 0.71 1.0931 0.9965 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 O24 mock treatment 581176.0 -163000.0 -0.35 524043.0 -259000.0 -0.59 -0.6604 -0.9676 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P01 compound treatment 418070.0 -326000.0 -0.69 456647.0 -326000.0 -0.74 -1.0133 -0.9994 1584127 Maybridge3_004203 CCOC(=O)C1=C(NC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P02 compound treatment 474196.0 -270000.0 -0.57 751601.0 -31500.0 -0.07 -0.455 -0.7894 1515716 Maybridge3_004204 COc1ccc(NC(=O)c2ccc3ncccc3c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P03 compound treatment 1093275.0 349000.0 0.74 991293.0 208000.0 0.47 0.8584 0.9766 2077417 Maybridge3_004205 FC(F)(F)Oc1ccc(CC2SC(=N)NC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P04 compound treatment 1128139.0 384000.0 0.81 1002108.0 219000.0 0.5 0.928 0.9721 2077418 Maybridge3_004206 COc1ccc(cc1)c2cc(n3nccc3n2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P05 compound treatment 1013260.0 269000.0 0.57 1016241.0 233000.0 0.53 0.7785 0.9993 1126864 Maybridge3_004207 OC(=O)c1c(nnc2ccccc12)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P06 compound treatment 1059881.0 316000.0 0.67 1058868.0 276000.0 0.63 0.917 0.9995 1447911 Maybridge3_004208 O=C(NC1Cc2ccccc2C1)c3ccc4nonc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P07 compound treatment 951421.0 207000.0 0.44 911953.0 129000.0 0.29 0.5182 0.9805 2077419 Maybridge3_004209 CCCN(Cc1ccco1)S(=O)(=O)c2ccc(OC)c(OC)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P08 compound treatment 999524.0 256000.0 0.54 893843.0 111000.0 0.25 0.5612 0.9393 1328406 Maybridge3_004210 O=C(CSC1=NCCS1)NC2Cc3ccccc3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P09 compound treatment 700226.0 -43700.0 -0.09 761127.0 -21900.0 -0.05 -0.1008 -0.9577 2077420 Maybridge3_004211 COc1ccc(cc1OC2CCCC2)S(=O)(=O)NCc3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P10 compound treatment 956774.0 213000.0 0.45 882635.0 99600.0 0.23 0.4791 0.9491 2077421 Maybridge3_004212 C=CCn1c(SCC#N)nnc1c2ccc3ncccc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P11 compound treatment 731194.0 -12800.0 -0.03 782048.0 -1020.0 0.0 -0.0208 -0.7647 1510724 Maybridge3_004213 OC(=O)CCN(Cc1ccco1)S(=O)(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P12 compound treatment 579348.0 -165000.0 -0.35 768697.0 -14400.0 -0.03 -0.2699 -0.7699 2077422 Maybridge3_004214 CCOC(=O)c1ccc2nc(cc(N3CCN(C)CC3)c2c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P13 compound treatment 566002.0 -178000.0 -0.38 798491.0 15400.0 0.04 -0.242 -0.6386 2077423 Maybridge3_004215 FC(F)(F)c1cc(nc2cc(nn12)C3CC3)c4ccccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P14 compound treatment 588474.0 -155000.0 -0.33 800400.0 17300.0 0.04 -0.2052 -0.6182 1372489 Maybridge3_004216 CN1CCN(CC1)S(=O)(=O)c2ccc(CNC(=O)c3ccccc3)s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P15 compound treatment 691383.0 -52600.0 -0.11 880433.0 97400.0 0.22 0.0777 0.3135 2077424 Maybridge3_004217 FC(F)(F)c1cccc(OC(=O)c2ccc3nonc3c2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P16 compound treatment 787438.0 43500.0 0.09 870748.0 87700.0 0.2 0.2061 0.9385 1348162 Maybridge3_004218 Cc1cc(C)c2cc([nH]c2c1)C(=O)NCCN3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P17 compound treatment 723113.0 -20900.0 -0.04 960017.0 177000.0 0.4 0.2532 0.6256 2077425 Maybridge3_004219 FC(F)(F)c1cc(no1)c2ccc(s2)S(=O)(=O)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P18 compound treatment 643095.0 -101000.0 -0.21 858840.0 75800.0 0.17 -0.0294 -0.1071 1553305 Maybridge3_004220 Clc1ccc2c(ccnc2c1)N3CCN(CC3)S(=O)(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P19 compound treatment 874770.0 131000.0 0.28 986142.0 203000.0 0.46 0.5225 0.9702 2077426 Maybridge3_004221 CCOC(=O)C1CCN(CC1)c2cc(nc3ccccc23)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P20 compound treatment 725678.0 -18300.0 -0.04 855402.0 72300.0 0.16 0.0889 0.526 1155426 Maybridge3_004222 CC(=O)N1CCN(CC1)c2ccnc3cc(Cl)ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P21 compound treatment 708009.0 -36000.0 -0.08 889596.0 107000.0 0.24 0.1174 0.4622 1324782 Maybridge3_004223 COc1ccc(cc1OC(C)C)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P22 compound treatment 576858.0 -167000.0 -0.35 770827.0 -12200.0 -0.03 -0.2702 -0.7603 2077427 Maybridge3_004224 FC(F)(F)c1cc(N2CCN(CC2)C(=O)Cc3ccccc3)c4ccccc4n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P23 mock treatment 525694.0 -218000.0 -0.46 567758.0 -215000.0 -0.49 -0.6733 -0.9996 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1442 P24 mock treatment 453984.0 -290000.0 -0.61 501613.0 -281000.0 -0.64 -0.8872 -0.9998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A01 compound treatment 364322.0 -337000.0 -0.71 405976.0 -414000.0 -0.94 -1.1709 -0.9907 2077828 Maybridge3_004929 CN(C)C(=O)Oc1noc2ccc(C)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A02 compound treatment 424462.0 -277000.0 -0.59 396670.0 -424000.0 -0.96 -1.0957 -0.9717 1668297 Maybridge3_004930 Oc1nc(nc2CCSCc12)c3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A03 compound treatment 490606.0 -210000.0 -0.45 481092.0 -339000.0 -0.77 -0.8608 -0.9662 1313901 Maybridge3_004931 CC(Oc1c(C)nccc1O)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A04 compound treatment 597661.0 -103000.0 -0.22 510636.0 -310000.0 -0.7 -0.6529 -0.8854 2077829 Maybridge3_004932 CNc1nc2cc(Cl)ccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A05 compound treatment 561747.0 -139000.0 -0.3 439214.0 -381000.0 -0.87 -0.8215 -0.8975 2077830 Maybridge3_004933 CC(C)(C)c1ccc(NC(=O)C2CC2)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A06 compound treatment 645496.0 -55600.0 -0.12 437052.0 -383000.0 -0.87 -0.6994 -0.7955 2077831 Maybridge3_004934 Cn1cc(Cl)c(/C=C(\C#N)/S(=O)(=O)c2ccccc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A07 compound treatment 575793.0 -125000.0 -0.27 517199.0 -303000.0 -0.69 -0.6751 -0.9141 2077832 Maybridge3_004935 Oc1ncc(Oc2ccc(Cl)cc2Cl)cn1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A08 compound treatment 497069.0 -204000.0 -0.43 525853.0 -294000.0 -0.67 -0.7792 -0.9777 2077833 Maybridge3_004936 Cn1cc(Cl)c(n1)c2nc(cs2)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A09 compound treatment 642691.0 -58400.0 -0.12 447561.0 -373000.0 -0.85 -0.6868 -0.8019 2077834 Maybridge3_004937 CS/C(=N\C#N)/NC1(CC2CC3CC(C2)C1)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A10 compound treatment 499709.0 -201000.0 -0.43 495757.0 -325000.0 -0.74 -0.8236 -0.9662 2077835 Maybridge3_004938 CNC(=O)OC(C)(C)C#Cc1cncnc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A11 compound treatment 512512.0 -189000.0 -0.4 563542.0 -257000.0 -0.58 -0.6954 -0.983 1072389 Maybridge3_004939 COC(=O)c1cc(OC)nc(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A12 compound treatment 467662.0 -233000.0 -0.49 433535.0 -387000.0 -0.88 -0.9717 -0.963 2077836 Maybridge3_004940 Cn1nc(cc1C(=O)Nc2ccc(Cl)cc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A13 compound treatment 546417.0 -155000.0 -0.33 442171.0 -378000.0 -0.86 -0.8397 -0.9127 2077837 Maybridge3_004941 Oc1ccc(Oc2c(Cl)cncc2Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A14 compound treatment 548536.0 -153000.0 -0.32 499793.0 -320000.0 -0.73 -0.7439 -0.9332 2077838 Maybridge3_004942 CCN(C(=O)c1cnccc1C(F)(F)F)c2cccc(C)c2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A15 compound treatment 601572.0 -99500.0 -0.21 550823.0 -269000.0 -0.61 -0.5824 -0.8988 1625339 Maybridge3_004943 Nc1nc(O)nc(n1)C2CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A16 compound treatment 614124.0 -87000.0 -0.18 574956.0 -245000.0 -0.56 -0.5248 -0.8933 2077839 Maybridge3_004944 Cn1nc(O)c2c(ccnc12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A17 compound treatment 590402.0 -111000.0 -0.23 428892.0 -391000.0 -0.89 -0.7951 -0.864 2077840 Maybridge3_004945 Cc1cc(NCc2ccccc2)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A18 compound treatment 540789.0 -160000.0 -0.34 482092.0 -338000.0 -0.77 -0.784 -0.9326 2077841 Maybridge3_004946 Cc1ccc(cc1)c2nnnn2c3ccccc3C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A19 compound treatment 644669.0 -56400.0 -0.12 598851.0 -221000.0 -0.5 -0.4406 -0.8514 2077842 Maybridge3_004947 CC(C)(C)C(=O)OCC(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A20 compound treatment 513341.0 -188000.0 -0.4 539687.0 -281000.0 -0.64 -0.7325 -0.9742 2077843 Maybridge3_004948 CCN(C(=O)c1c(OC)nccc1C(F)(F)F)c2c(C)cccc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A21 compound treatment 465867.0 -235000.0 -0.5 522976.0 -297000.0 -0.68 -0.8306 -0.9888 1028520 Maybridge3_004949 CCSc1nc(O)cc(n1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A22 compound treatment 444968.0 -256000.0 -0.54 509429.0 -311000.0 -0.71 -0.8837 -0.9915 2077844 Maybridge3_004950 CN(C(=O)c1cnc(O)cc1C(F)(F)F)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A23 mock treatment 431925.0 -269000.0 -0.57 484098.0 -336000.0 -0.76 -0.944 -0.9896 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 A24 mock treatment 367740.0 -333000.0 -0.71 467391.0 -353000.0 -0.8 -1.067 -0.998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B01 compound treatment 393870.0 -307000.0 -0.65 384693.0 -436000.0 -0.99 -1.1608 -0.9793 2077845 Maybridge3_004951 CCOC(=O)c1c(C)n[nH]c1SC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B02 compound treatment 688578.0 -12500.0 -0.03 532078.0 -288000.0 -0.66 -0.4821 -0.7351 1631011 Maybridge3_004952 Cc1ccc2ncnc(Oc3ncccc3NC(=O)C(C)(C)C)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B03 compound treatment 914030.0 213000.0 0.45 901531.0 81300.0 0.18 0.4498 0.9222 2077846 Maybridge3_004953 NC(=O)c1c(O)nccc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B04 compound treatment 865092.0 164000.0 0.35 880980.0 60700.0 0.14 0.3434 0.9181 2077847 Maybridge3_004954 Nc1cccnc1Sc2nc3cccnc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B05 compound treatment 1078956.0 378000.0 0.8 1100840.0 281000.0 0.64 1.0175 0.9936 2077848 Maybridge3_004955 CCC(=O)Nc1cc(cnc1OC)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B06 compound treatment 859731.0 159000.0 0.34 960720.0 140000.0 0.32 0.4636 0.9997 1690665 Maybridge3_004956 Oc1cc(=O)oc2c3ccccc3n(c4ccccc4)c(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B07 compound treatment 863069.0 162000.0 0.34 908047.0 87800.0 0.2 0.3839 0.9667 2077849 Maybridge3_004957 FC(F)(F)c1cccc(c1)n2c(noc2=O)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B08 compound treatment 977304.0 276000.0 0.59 936673.0 116000.0 0.26 0.6012 0.9356 2077850 Maybridge3_004958 CC(NCc1ccccc1O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B09 compound treatment 1023652.0 323000.0 0.68 966473.0 146000.0 0.33 0.7185 0.9451 2077851 Maybridge3_004959 Nc1cnc(Oc2c(Cl)cccc2Cl)c(c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B10 compound treatment 1029672.0 329000.0 0.7 930372.0 110000.0 0.25 0.6695 0.9046 1019826 Maybridge3_004960 O=C1CCCN1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B11 compound treatment 1096945.0 396000.0 0.84 998692.0 178000.0 0.41 0.8802 0.9444 2077852 Maybridge3_004961 CC(C)(C)c1ccc(cc1)c2noc(n2)c3ccno3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B12 compound treatment 1137468.0 436000.0 0.93 997311.0 177000.0 0.4 0.9387 0.9305 2077853 Maybridge3_004962 CSc1nc(c(C#N)c(=O)[nH]1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B13 compound treatment 965920.0 265000.0 0.56 986527.0 166000.0 0.38 0.6642 0.9815 2077854 Maybridge3_004963 Clc1ccc(cc1)c2csc(n2)c3[nH]ncc3Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B14 compound treatment 815480.0 114000.0 0.24 858803.0 38500.0 0.09 0.2334 0.9053 2077855 Maybridge3_004964 COc1c2CCCc2c(C)cc1/C(=N/O)/N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B15 compound treatment 843299.0 142000.0 0.3 980265.0 160000.0 0.36 0.4704 0.9956 1031000 Maybridge3_004965 O=c1cc(oc2ccccc12)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B16 compound treatment 895448.0 194000.0 0.41 900582.0 80300.0 0.18 0.4204 0.9329 2077856 Maybridge3_004966 COc1ccccc1c2nnc(SC)n2c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B17 compound treatment 806723.0 106000.0 0.22 930357.0 110000.0 0.25 0.3353 0.9985 2077857 Maybridge3_004967 Cn1c(=O)c(C#N)c(c2cccs2)n3cnnc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B18 compound treatment 876550.0 175000.0 0.37 837122.0 16800.0 0.04 0.2901 0.7758 1193356 Maybridge3_004968 CCNc1nc2ccc(Cl)cc2nc1NCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B19 compound treatment 921555.0 220000.0 0.47 922933.0 103000.0 0.23 0.4955 0.9485 2077858 Maybridge3_004969 COc1ccc(OC)c(Sc2ccc3nnc(c4ccccc4)n3n2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B20 compound treatment 924043.0 223000.0 0.47 882429.0 62100.0 0.14 0.4341 0.88 2077859 Maybridge3_004970 C(N1CCCCC1)c2nnc(o2)c3cccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B21 compound treatment 822480.0 121000.0 0.26 897254.0 77000.0 0.18 0.3057 0.9824 1372286 Maybridge3_004971 COC(CSc1nc2cccc(F)c2c(=O)n1c3ccc(C)c(C)c3)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B22 compound treatment 832042.0 131000.0 0.28 828764.0 8480.0 0.02 0.2099 0.7544 1255927 Maybridge3_004972 O=C(NC1CCN(CCc2c[nH]c3ccccc23)CC1)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B23 mock treatment 707913.0 6810.0 0.01 744887.0 -75400.0 -0.17 -0.111 -0.6452 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 B24 mock treatment 408214.0 -293000.0 -0.62 445562.0 -375000.0 -0.85 -1.0415 -0.9879 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C01 compound treatment 428131.0 -273000.0 -0.58 475186.0 -345000.0 -0.78 -0.964 -0.9888 1454544 Maybridge3_004973 CC(C)(C)NC(=O)Oc1noc2cc(Cl)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C02 compound treatment 647785.0 -53300.0 -0.11 774766.0 -45500.0 -0.1 -0.1531 -0.999 2077860 Maybridge3_004974 Clc1ccc(/N=C/c2ccn(n2)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C03 compound treatment 896843.0 196000.0 0.41 908038.0 87800.0 0.2 0.4345 0.9437 1261257 Maybridge3_004975 Cc1onc(c1C(=O)Oc2noc3ccccc23)c4c(Cl)cccc4Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C04 compound treatment 937707.0 237000.0 0.5 981149.0 161000.0 0.37 0.6133 0.988 1283591 Maybridge3_004976 CCNc1nc2cc(Cl)ccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C05 compound treatment 932342.0 231000.0 0.49 905782.0 85500.0 0.19 0.4841 0.918 1234934 Maybridge3_004977 Nc1nnc(O)c2cc(nc(O)c12)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C06 compound treatment 1222566.0 521000.0 1.11 1031755.0 211000.0 0.48 1.1217 0.9305 2077861 Maybridge3_004978 FC(F)(F)c1ccncc1c2nnc(o2)C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C07 compound treatment 971325.0 270000.0 0.57 955104.0 135000.0 0.31 0.6218 0.9571 2077862 Maybridge3_004979 Clc1ccc(cc1)C2=CSC(=C(C#N)C#N)S2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C08 compound treatment 970080.0 269000.0 0.57 1054029.0 234000.0 0.53 0.779 0.9994 2077863 Maybridge3_004980 CC(C)NC(=O)OCc1noc(n1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C09 compound treatment 1032861.0 332000.0 0.7 959037.0 139000.0 0.32 0.7204 0.9346 2077864 Maybridge3_004981 COC(=O)c1snc(c1C(=O)OC)c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C10 compound treatment 881473.0 180000.0 0.38 1064914.0 245000.0 0.56 0.6637 0.9833 2077865 Maybridge3_004982 Cc1nc(c2noc(n2)c3cccc(Cl)c3)c(o1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C11 compound treatment 1055665.0 355000.0 0.75 989672.0 169000.0 0.39 0.8038 0.9517 2077866 Maybridge3_004983 CN(C)N/C(=N\O)/c1c(Cl)cccc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C12 compound treatment 1143439.0 442000.0 0.94 1362744.0 542000.0 1.23 1.5352 0.9909 2077867 Maybridge3_004984 Clc1ccc(cc1)c2cc(on2)c3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C13 compound treatment 1073252.0 372000.0 0.79 1299875.0 480000.0 1.09 1.3289 0.9874 1565017 Maybridge3_004985 COc1nc(N)nc(n1)C2CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C14 compound treatment 929765.0 229000.0 0.48 988701.0 168000.0 0.38 0.6135 0.9932 1138067 Maybridge3_004986 COC(=O)C(CC(=O)c1cccs1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C15 compound treatment 884990.0 184000.0 0.39 1121198.0 301000.0 0.68 0.7594 0.9644 1584990 Maybridge3_004987 COc1nc(N)nc(n1)C2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C16 compound treatment 975423.0 274000.0 0.58 999602.0 179000.0 0.41 0.6995 0.9849 2077868 Maybridge3_004988 CCN(Cc1ccc(OC)cc1OC)C(=O)c2cnc(OC)cc2C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C17 compound treatment 1033361.0 332000.0 0.7 896740.0 76500.0 0.17 0.621 0.8559 2077869 Maybridge3_004989 OCc1nc(cs1)c2ccc(cc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C18 compound treatment 1068026.0 367000.0 0.78 1030065.0 210000.0 0.48 0.8873 0.9724 2077870 Maybridge3_004990 Cc1cccc(C)c1n2nnnc2c3cnccc3C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C19 compound treatment 1029732.0 329000.0 0.7 975008.0 155000.0 0.35 0.7414 0.9499 1691304 Maybridge3_004991 CC(C)(O)C(=O)OCC(=O)c1ccc(Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C20 compound treatment 1098667.0 398000.0 0.84 1033280.0 213000.0 0.48 0.9384 0.9654 2077871 Maybridge3_004992 COC(=O)c1cncc(Br)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C21 compound treatment 988263.0 287000.0 0.61 1026068.0 206000.0 0.47 0.7613 0.9915 2077872 Maybridge3_004993 CSc1nc(C)nc(c1C#N)n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C22 compound treatment 968932.0 268000.0 0.57 946150.0 126000.0 0.29 0.6038 0.9497 2077873 Maybridge3_004994 CC1(OCCO1)C2(C)OCCO2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C23 mock treatment 806776.0 106000.0 0.22 947473.0 127000.0 0.29 0.3629 0.992 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 C24 mock treatment 470803.0 -230000.0 -0.49 555568.0 -265000.0 -0.6 -0.7708 -0.9946 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D01 compound treatment 458350.0 -243000.0 -0.51 538023.0 -282000.0 -0.64 -0.8177 -0.994 2077874 Maybridge3_004995 FC(F)(F)COc1ncccc1C(=O)NCc2ccc(Cl)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D02 compound treatment 791049.0 90000.0 0.19 902735.0 82500.0 0.19 0.2674 1.0 2077875 Maybridge3_004996 C1CC1n2nnc3cccnc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D03 compound treatment 893882.0 193000.0 0.41 1023211.0 203000.0 0.46 0.6152 0.9982 2077876 Maybridge3_004997 CC(C)C(=O)NCc1c(C)cc(Cl)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D04 compound treatment 906471.0 205000.0 0.44 1107277.0 287000.0 0.65 0.7692 0.9807 1333573 Maybridge3_004998 CCOC(=O)c1cc(=O)c2ccc(OC(=O)c3cccs3)cc2o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D05 compound treatment 939227.0 238000.0 0.5 1205603.0 385000.0 0.88 0.9764 0.9657 1519109 Maybridge3_004999 Clc1ccc(c2noc(=O)n2c3cccnc3)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D06 compound treatment 1094252.0 393000.0 0.83 1388036.0 568000.0 1.29 1.5021 0.9776 2077877 Maybridge3_005000 CCCCc1ccc(N/C=N/O)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D07 compound treatment 926235.0 225000.0 0.48 1009729.0 189000.0 0.43 0.6421 0.9987 1380506 Maybridge3_005001 O=c1onc(c2cccnc2)n1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D08 compound treatment 913953.0 213000.0 0.45 960125.0 140000.0 0.32 0.5439 0.9853 2077878 Maybridge3_005002 CC(C)CC(NCc1ccccc1O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D09 compound treatment 900126.0 199000.0 0.42 919551.0 99300.0 0.23 0.4579 0.957 2077879 Maybridge3_005003 Nc1ccc(OCC(F)(F)F)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D10 compound treatment 988350.0 287000.0 0.61 1410102.0 590000.0 1.34 1.3788 0.9362 1303968 Maybridge3_005004 CCCCc1cc(C)c2[nH]c(=O)cc(C)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D11 compound treatment 851291.0 150000.0 0.32 1287172.0 467000.0 1.06 0.9757 0.8805 2077880 Maybridge3_005005 Cc1coc(=O)n1c2ccc(Cl)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D12 compound treatment 956832.0 256000.0 0.54 1740513.0 920000.0 2.09 1.8628 0.8619 1539028 Maybridge3_005006 COc1ccc(N(C)CC(=O)O)c(c1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D13 compound treatment 1305788.0 605000.0 1.28 1556306.0 736000.0 1.67 2.0897 0.9913 1409985 Maybridge3_005007 CSc1ccncc1C(=O)Nc2cc(Cl)cc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D14 compound treatment 1035453.0 334000.0 0.71 967162.0 147000.0 0.33 0.7373 0.941 2077881 Maybridge3_005008 CC1Sc2ccc(cc2NC1=O)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D15 compound treatment 349112.0 -352000.0 -0.75 381754.0 -439000.0 -1.0 -1.2326 -0.9898 2077882 Maybridge3_005009 Oc1ccccc1c2cc(n[nH]2)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D16 compound treatment 845034.0 144000.0 0.31 1135917.0 316000.0 0.72 0.7232 0.9274 1138183 Maybridge3_005010 O=C(Nc1nc-2c(Cc3ccccc23)s1)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D17 compound treatment 947540.0 246000.0 0.52 964522.0 144000.0 0.33 0.6013 0.9748 1196135 Maybridge3_005011 CCOC(=O)c1cnn2c1[nH]c(=O)c3ccccc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D18 compound treatment 889346.0 188000.0 0.4 1005180.0 185000.0 0.42 0.5794 0.9997 1725366 Maybridge3_005012 CN(C(=O)COc1cc(C)c2C(=O)CC(C)(C)Oc2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D19 compound treatment 850057.0 149000.0 0.32 988693.0 168000.0 0.38 0.494 0.9954 2077883 Maybridge3_005013 CCOC(=O)CSc1ccc2nnc(c3ccccc3)n2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D20 compound treatment 913240.0 212000.0 0.45 928130.0 108000.0 0.25 0.4914 0.9593 2077884 Maybridge3_005014 CN1CC2CCC1CC(C2)NC(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D21 compound treatment 885492.0 184000.0 0.39 792298.0 -28000.0 -0.06 0.2314 0.5843 2077885 Maybridge3_005015 Cc1cc(C=C2C(=O)CC(C)(C)CC2=O)oc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D22 compound treatment 693200.0 -7900.0 -0.02 862342.0 42100.0 0.1 0.0558 0.5746 1318276 Maybridge3_005016 COc1ccccc1C2CCN(CC2)C(=O)c3ccc(N)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D23 mock treatment 688600.0 -12500.0 -0.03 806415.0 -13900.0 -0.03 -0.041 -0.9963 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 D24 mock treatment 487834.0 -213000.0 -0.45 572731.0 -248000.0 -0.56 -0.7177 -0.9941 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E01 compound treatment 508008.0 -193000.0 -0.41 610318.0 -210000.0 -0.48 -0.627 -0.9971 1601560 Maybridge3_005017 CCCNC(=O)Oc1noc2ccc(Cl)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E02 compound treatment 809365.0 108000.0 0.23 1043181.0 223000.0 0.51 0.5206 0.9358 2077886 Maybridge3_005018 Oc1nc(nc2CCSCc12)c3ccc(cc3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E03 compound treatment 1131196.0 430000.0 0.91 1126158.0 306000.0 0.7 1.1365 0.9911 2077887 Maybridge3_005019 O/N=C/c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E04 compound treatment 1001561.0 300000.0 0.64 1038064.0 218000.0 0.5 0.8005 0.9922 2077888 Maybridge3_005020 CN(C(=O)c1cnccc1C(F)(F)F)c2nc3cc(Cl)ccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E05 compound treatment 912897.0 212000.0 0.45 1073337.0 253000.0 0.58 0.7243 0.9925 2077889 Maybridge3_005021 Cc1nc(nc(O)c1Cl)C2CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E06 compound treatment 1151615.0 451000.0 0.96 1172388.0 352000.0 0.8 1.2414 0.9961 2077890 Maybridge3_005022 FC(F)(F)c1ccncc1c2ncc(o2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E07 compound treatment 1148957.0 448000.0 0.95 1044000.0 224000.0 0.51 1.031 0.9572 2077891 Maybridge3_005023 CS/C(=N\C#N)/NCc1ccco1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E08 compound treatment 1018550.0 317000.0 0.67 1164018.0 344000.0 0.78 1.0285 0.9972 2077892 Maybridge3_005024 CCOc1cccc(NC(=O)c2nc(C)oc2C(F)(F)F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E09 compound treatment 1057429.0 356000.0 0.76 997541.0 177000.0 0.4 0.8191 0.9567 2077893 Maybridge3_005025 CSc1nnc([nH]1)C2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E10 compound treatment 1256111.0 555000.0 1.18 1421666.0 601000.0 1.37 1.7988 0.9972 2077894 Maybridge3_005026 CCN(C(=O)c1cnc(OC)cc1C(F)(F)F)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E11 compound treatment 1172378.0 471000.0 1.0 1301732.0 481000.0 1.09 1.4805 0.999 1287188 Maybridge3_005027 Oc1nsc(Nc2ccc(Cl)cc2)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E12 compound treatment 1250594.0 549000.0 1.16 1703638.0 883000.0 2.01 2.2438 0.9664 2077895 Maybridge3_005028 COc1ccc(CNC(=O)c2cnc(OC)cc2C(F)(F)F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E13 compound treatment 1063130.0 362000.0 0.77 1630868.0 811000.0 1.84 1.8458 0.9246 2077896 Maybridge3_005029 CN(C)c1nc(C)nc(N)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E14 compound treatment 1096205.0 395000.0 0.84 1412162.0 592000.0 1.35 1.5438 0.974 2077897 Maybridge3_005030 CCSc1cc(c(cn1)C(=O)Nc2ccc(Cl)cc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E15 compound treatment 1038386.0 337000.0 0.72 1131284.0 311000.0 0.71 1.0056 1.0 1922922 Maybridge3_005031 OCc1nc(cs1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E16 compound treatment 1316034.0 615000.0 1.3 1147789.0 328000.0 0.74 1.4483 0.9647 2077898 Maybridge3_005032 NC(=O)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E17 compound treatment 988694.0 288000.0 0.61 1080195.0 260000.0 0.59 0.849 0.9999 2077899 Maybridge3_005033 CSc1nc(N)nc(n1)c2ccc(cc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E18 compound treatment 1145980.0 445000.0 0.94 1090903.0 271000.0 0.62 1.102 0.9786 2077900 Maybridge3_005034 OC(=O)c1c(O)nccc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E19 compound treatment 1079188.0 378000.0 0.8 1042170.0 222000.0 0.5 0.9235 0.9751 2077901 Maybridge3_005035 Clc1ccc(/C=N/Cc2cccnc2)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E20 compound treatment 1157089.0 456000.0 0.97 966373.0 146000.0 0.33 0.9184 0.8985 2077902 Maybridge3_005036 CCN(Cc1cc(OC)cc(OC)c1)C(=O)c2c(OC)nccc2C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E21 compound treatment 1123392.0 422000.0 0.9 941443.0 121000.0 0.28 0.8278 0.8838 2077903 Maybridge3_005037 Fc1ccc(SC(=O)Nc2ccccc2)c(F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E22 compound treatment 941872.0 241000.0 0.51 960558.0 140000.0 0.32 0.5864 0.9744 2077904 Maybridge3_005038 FC(F)(F)c1cc(Cl)c2nnc(CNC(=O)c3ccccc3)n2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E23 mock treatment 725029.0 23900.0 0.05 806753.0 -13500.0 -0.03 0.0141 0.2381 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 E24 mock treatment 498979.0 -202000.0 -0.43 483304.0 -337000.0 -0.77 -0.8447 -0.9623 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F01 compound treatment 902879.0 202000.0 0.43 987807.0 168000.0 0.38 0.5718 0.9983 2077905 Maybridge3_005039 CN(C)C(=O)c1ccc(OCC(F)(F)F)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F02 compound treatment 1031235.0 330000.0 0.7 1223212.0 403000.0 0.92 1.1427 0.9912 3177834 Maybridge3_005040 CC1CN(Cc2ccccc2)CCN1.OC(=O)/C=C/C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F03 compound treatment 1086111.0 385000.0 0.82 1287507.0 467000.0 1.06 1.3283 0.9915 2077907 Maybridge3_005041 CCSc1nccc(c1C(=O)Nc2ccc(Cl)cc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F04 compound treatment 1142562.0 441000.0 0.94 1097031.0 277000.0 0.63 1.1067 0.9813 1568121 Maybridge3_005042 Clc1ccc2c(ccnc2c1)N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F05 compound treatment 1130288.0 429000.0 0.91 1135073.0 315000.0 0.72 1.1494 0.9929 1705288 Maybridge3_005043 Clc1cccc(c2noc(=O)n2c3cccnc3)c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F06 compound treatment 1103232.0 402000.0 0.85 1249202.0 429000.0 0.98 1.2924 0.9978 2077908 Maybridge3_005044 O=C1/C(=C/c2ccccc2)/Cc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F07 compound treatment 960295.0 259000.0 0.55 1649046.0 829000.0 1.88 1.7209 0.8768 1434016 Maybridge3_005045 COc1ccc(cc1)c2noc(=O)n2c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F08 compound treatment 874107.0 173000.0 0.37 1140212.0 320000.0 0.73 0.7737 0.9497 2077909 Maybridge3_005046 CSCCC(NCc1ccccc1O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F09 compound treatment 1102249.0 401000.0 0.85 1303622.0 483000.0 1.1 1.3784 0.992 2077910 Maybridge3_005047 Nc1ccc(Sc2ccccc2)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F10 compound treatment 1304874.0 604000.0 1.28 1442647.0 622000.0 1.41 1.9056 0.9987 2077911 Maybridge3_005048 CC1=N/C(=C/c2ccc(C)cc2)/C(=O)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F11 compound treatment 1209502.0 508000.0 1.08 2458455.0 1640000.0 3.72 3.3957 0.8758 2077912 Maybridge3_005049 COc1cccc(OC)c1CN(C)C(=O)c2cnc(OC(C)C)cc2C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F12 compound treatment 1692917.0 992000.0 2.1 2251728.0 1430000.0 3.25 3.788 0.9777 2077913 Maybridge3_005050 Cc1c(sc2ccccc12)C(=O)CSc3ncccc3C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F13 compound treatment 1583142.0 882000.0 1.87 1867398.0 1050000.0 2.38 3.0056 0.9929 1382721 Maybridge3_005051 CN(C)c1ccncc1C(=O)Nc2cc(Cl)cc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F14 compound treatment 1445522.0 744000.0 1.58 2214471.0 1390000.0 3.17 3.3573 0.9481 1010987 Maybridge3_005052 O=C1C(c2ccccc2N1Cc3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F15 compound treatment 1011246.0 310000.0 0.66 1189379.0 369000.0 0.84 1.0583 0.9927 2077914 Maybridge3_005053 Cc1cc(C)c(c2cc([nH]n2)c3ccccc3Cl)c(O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F16 compound treatment 1114347.0 413000.0 0.88 1559537.0 739000.0 1.68 1.8079 0.9539 2077915 Maybridge3_005054 CCOC(=O)c1ccccc1NC(=O)CSc2ncccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F17 compound treatment 1212175.0 511000.0 1.08 1695298.0 875000.0 1.99 2.1728 0.9592 1507326 Maybridge3_005055 CCOC(=O)c1cnn2c1nc(N)c3ccccc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F18 compound treatment 1094356.0 393000.0 0.83 1430871.0 611000.0 1.39 1.5711 0.9702 1373326 Maybridge3_005056 Cc1cc(OCC(=O)O)cc2OC(C)(C)CC(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F19 compound treatment 1195851.0 495000.0 1.05 1578631.0 758000.0 1.72 1.9608 0.9716 2077916 Maybridge3_005057 OCCSc1ccc2nnc(c3ccccc3)n2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F20 compound treatment 1118680.0 418000.0 0.89 1272385.0 452000.0 1.03 1.3528 0.9972 1479693 Maybridge3_005058 COc1cc(ccc1O)c2onc3ccc(Cl)cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F21 compound treatment 907249.0 206000.0 0.44 1373970.0 554000.0 1.26 1.1992 0.8999 2077917 Maybridge3_005059 CSc1nc2cc(Cl)c(Cl)cc2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F22 compound treatment 1141994.0 441000.0 0.93 1143174.0 323000.0 0.73 1.18 0.9929 2077918 Maybridge3_005060 COC(=O)C1(C)Cc2c([nH]c3ccccc23)C(N1)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F23 mock treatment 1141844.0 441000.0 0.93 987176.0 167000.0 0.38 0.929 0.9212 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 F24 mock treatment 469470.0 -232000.0 -0.49 621908.0 -198000.0 -0.45 -0.6661 -0.9991 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G01 compound treatment 960049.0 259000.0 0.55 861119.0 40800.0 0.09 0.4538 0.8151 1172405 Maybridge3_005061 CCN(CC)OC(=O)Nc1c(C)onc1c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G02 compound treatment 1024502.0 323000.0 0.69 1240991.0 421000.0 0.96 1.1611 0.9867 2077919 Maybridge3_005062 Cn1cc(Cl)c(/C=N/O)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G03 compound treatment 1028206.0 327000.0 0.69 1185399.0 365000.0 0.83 1.0773 0.996 1049120 Maybridge3_005063 CC(=O)Nc1ccc(cc1Br)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G04 compound treatment 1030950.0 330000.0 0.7 1134137.0 314000.0 0.71 0.999 0.9999 2077920 Maybridge3_005064 CC(C)OC(=O)Nc1cnccc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G05 compound treatment 1010683.0 310000.0 0.66 1036261.0 216000.0 0.49 0.8113 0.9898 2077921 Maybridge3_005065 Cc1nc(nc(O)c1Cl)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G06 compound treatment 1429839.0 729000.0 1.54 1632819.0 813000.0 1.85 2.3987 0.996 2077922 Maybridge3_005066 Cn1cc(Cl)c(/C=C(\C#N)/S(=O)(=O)C(C)(C)C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G07 compound treatment 1297003.0 596000.0 1.26 1683497.0 863000.0 1.96 2.281 0.9773 2077923 Maybridge3_005067 CS/C(=N/C#N)/NCc1cccs1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G08 compound treatment 1141189.0 440000.0 0.93 1482284.0 662000.0 1.51 1.724 0.9736 2077924 Maybridge3_005068 Cc1nc(c2ncc(o2)c3ccccc3)c(o1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G09 compound treatment 1276290.0 575000.0 1.22 1847270.0 1030000.0 2.33 2.5133 0.9541 2077925 Maybridge3_005069 Nc1n[nH]c(NCc2cccnc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G10 compound treatment 1251830.0 551000.0 1.17 1411438.0 591000.0 1.34 1.7759 0.9975 2077926 Maybridge3_005070 CCOc1cc(c(cn1)C(=O)N(CC)c2ccc(Cl)cc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G11 compound treatment 1385067.0 684000.0 1.45 1549737.0 729000.0 1.66 2.198 0.9978 2077927 Maybridge3_005071 COCc1cc(O)n(n1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G12 compound treatment 1242696.0 542000.0 1.15 1971029.0 1150000.0 2.62 2.6619 0.9317 2077928 Maybridge3_005072 COc1cc(c(cn1)C(=O)NCc2cccc(Cl)c2Cl)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G13 compound treatment 1421811.0 721000.0 1.53 1470441.0 650000.0 1.48 2.1256 0.9999 2077929 Maybridge3_005073 CSc1nc(N)nc(n1)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G14 compound treatment 1364298.0 663000.0 1.41 2120403.0 1300000.0 2.96 3.0843 0.9423 2077930 Maybridge3_005074 CNc1cc(c(cn1)C(=O)Nc2ccc(Cl)cc2Cl)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G15 compound treatment 1505965.0 805000.0 1.71 1700225.0 880000.0 2.0 2.6212 0.9969 2077931 Maybridge3_005075 CC(C)(C)C(=O)OCc1noc(n1)c2ccc(Cl)c(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G16 compound treatment 1455515.0 754000.0 1.6 1501005.0 681000.0 1.55 2.2253 0.9999 2077932 Maybridge3_005076 FC(F)(F)c1ccncc1c2nnnn2c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G17 compound treatment 1478485.0 777000.0 1.65 1561723.0 741000.0 1.69 2.3573 0.9999 1538786 Maybridge3_005077 Clc1ccc(CNCc2cccnc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G18 compound treatment 1165350.0 464000.0 0.98 1778485.0 958000.0 2.18 2.2364 0.9355 2077933 Maybridge3_005078 COc1nccc(c1C(=O)Nc2ccc(Cl)cc2Cl)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G19 compound treatment 1425580.0 724000.0 1.54 1550719.0 730000.0 1.66 2.2603 0.9992 2077934 Maybridge3_005079 OCc1nc(cs1)c2cccc(c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G20 compound treatment 1185435.0 484000.0 1.03 1499127.0 679000.0 1.54 1.8174 0.9804 1451821 Maybridge3_005080 O=C(Oc1ccc(CC#N)cc1)c2ccncc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G21 compound treatment 1181995.0 481000.0 1.02 1603861.0 784000.0 1.78 1.9806 0.9649 2077935 Maybridge3_005081 CNC(=S)Sc1ccc(F)cc1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G22 compound treatment 900193.0 199000.0 0.42 1168191.0 348000.0 0.79 0.8578 0.9567 2077936 Maybridge3_005082 OC(=O)c1ccc(OCC(F)(F)F)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G23 mock treatment 785079.0 84000.0 0.18 1163856.0 344000.0 0.78 0.6782 0.8466 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 G24 mock treatment 484406.0 -217000.0 -0.46 859052.0 38800.0 0.09 -0.2625 -0.5612 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H01 compound treatment 689534.0 -11600.0 -0.02 839752.0 19500.0 0.04 0.014 0.276 2077937 Maybridge3_005083 CCC(=O)NCc1ccc(Cl)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H02 compound treatment 965749.0 265000.0 0.56 1224674.0 404000.0 0.92 1.0468 0.9719 2077938 Maybridge3_005084 CSc1nc2cccnc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H03 compound treatment 1266962.0 566000.0 1.2 1177876.0 358000.0 0.81 1.4231 0.982 2077939 Maybridge3_005085 CCC(=O)Nc1cnc(OC)c(c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H04 compound treatment 1043043.0 342000.0 0.72 1260015.0 440000.0 1.0 1.2195 0.9875 1428554 Maybridge3_005086 CC(=CC(=O)Nc1nnc(Sc2ccnc3cc(Cl)ccc23)s1)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H05 compound treatment 1088959.0 388000.0 0.82 1098321.0 278000.0 0.63 1.0284 0.9916 2077940 Maybridge3_005087 COc1ccccc1N/C(=N\O)/c2ccccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H06 compound treatment 1499761.0 799000.0 1.69 1339920.0 520000.0 1.18 2.0326 0.9845 2077941 Maybridge3_005088 COC(=O)c1cccc(CSc2ncccc2C(=O)O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H07 compound treatment 949960.0 249000.0 0.53 1144101.0 324000.0 0.74 0.8936 0.9866 1679611 Maybridge3_005089 Fc1cccc(F)c1c2noc(=O)n2c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H08 compound treatment 1135586.0 434000.0 0.92 1695608.0 875000.0 1.99 2.0585 0.9387 1394439 Maybridge3_005090 COc1ccc(OC)c(c2cc[nH]n2)c1OCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H09 compound treatment 1388992.0 688000.0 1.46 1208788.0 389000.0 0.88 1.6558 0.9711 2077942 Maybridge3_005091 Nc1cnc(Sc2ccccc2)c(c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H10 compound treatment 1699876.0 999000.0 2.12 1663960.0 844000.0 1.92 2.8535 0.9988 2077943 Maybridge3_005092 COC(=O)c1cc(Br)c(Br)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H11 compound treatment 1356993.0 656000.0 1.39 1784710.0 964000.0 2.19 2.5337 0.9758 2077944 Maybridge3_005093 COc1cccc(OC)c1CN(C)C(=O)c2c(OC)nccc2C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H12 compound treatment 1915371.0 1210000.0 2.57 1830877.0 1010000.0 2.3 3.4449 0.9984 1367935 Maybridge3_005094 CC(=O)OC(C(=O)N(Cc1ccccc1)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H13 compound treatment 1103186.0 402000.0 0.85 1427848.0 608000.0 1.38 1.5795 0.9731 1194404 Maybridge3_005095 COc1ccncc1C(=O)Nc2cc(Cl)cc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H14 compound treatment 1079398.0 378000.0 0.8 1734606.0 914000.0 2.08 2.037 0.9142 1471887 Maybridge3_005096 CCOC(=O)c1c(C)n(C2CC2)c3ccc(O)cc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H15 compound treatment 1652782.0 952000.0 2.02 1926709.0 1110000.0 2.52 3.2053 0.994 2077945 Maybridge3_005097 Oc1ccccc1C(=O)CC(=O)c2c(F)cccc2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H16 compound treatment 1325081.0 624000.0 1.32 1743916.0 924000.0 2.1 2.4202 0.9752 1603605 Maybridge3_005098 Cc1cc(no1)C(=O)Nc2nc-3c(Cc4ccccc34)s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H17 compound treatment 1392894.0 692000.0 1.47 904425.0 84100.0 0.19 1.1723 0.7926 2077946 Maybridge3_005099 FC(F)(F)c1ccc(cc1)c2nnc3ccc(NC4CC4)nn23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H18 compound treatment 1289469.0 588000.0 1.25 1535673.0 715000.0 1.63 2.0321 0.9914 1736812 Maybridge3_005100 O=C(Nc1cccc(c1)C(=O)c2ccccc2)c3cccnc3Oc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H19 compound treatment 1285749.0 585000.0 1.24 1418845.0 599000.0 1.36 1.8387 0.9989 2077947 Maybridge3_005101 Clc1ccc(Oc2ccc3nnc(c4ccccc4)n3n2)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H20 compound treatment 1037702.0 337000.0 0.71 1264649.0 444000.0 1.01 1.219 0.9855 2077948 Maybridge3_005102 C(N1CCOCC1)c2nnc(o2)c3cccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H21 compound treatment 1114995.0 414000.0 0.88 1142749.0 322000.0 0.73 1.1389 0.996 1475594 Maybridge3_005103 Cc1ccc(CNc2ccc3nnc(c4ccccc4)n3n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H22 compound treatment 1002184.0 301000.0 0.64 983284.0 163000.0 0.37 0.7134 0.9666 2077949 Maybridge3_005104 CC(C)Oc1ccccc1C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H23 mock treatment 930670.0 230000.0 0.49 1032670.0 212000.0 0.48 0.6856 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 H24 mock treatment 564577.0 -137000.0 -0.29 767686.0 -52600.0 -0.12 -0.2892 -0.9235 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I01 compound treatment 674242.0 -26900.0 -0.06 894585.0 74300.0 0.17 0.0792 0.4442 2077950 Maybridge3_005105 CCN(CC)OC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I02 compound treatment 1217787.0 517000.0 1.1 1063119.0 243000.0 0.55 1.1649 0.9497 2077951 Maybridge3_005106 CC(C)Oc1cccc(NC(=O)c2cnccc2C(F)(F)F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I03 compound treatment 1303079.0 602000.0 1.28 1058385.0 238000.0 0.54 1.2852 0.9271 1510007 Maybridge3_005107 CC(=O)Nc1ccc(cc1C#N)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I04 compound treatment 1304709.0 604000.0 1.28 1146511.0 326000.0 0.74 1.4293 0.9664 2077952 Maybridge3_005108 CSc1nc(nc(N)c1C#N)c2ccncc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I05 compound treatment 1204319.0 503000.0 1.07 996306.0 176000.0 0.4 1.0373 0.9104 1669143 Maybridge3_005109 CC(C)(C)c1ccc(NC(=O)c2ccco2)c(N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I06 compound treatment 1867596.0 1170000.0 2.47 1307741.0 487000.0 1.11 2.5323 0.9345 2077953 Maybridge3_005110 FC(F)(F)c1ccncc1c2nc(no2)c3cc(Cl)cc(Cl)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I07 compound treatment 1771513.0 1070000.0 2.27 1195141.0 375000.0 0.85 2.2072 0.9106 1486142 Maybridge3_005111 CC(=O)Nc1cccc(c1)c2cc(no2)c3ccc(Cl)cc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I08 compound treatment 1294181.0 593000.0 1.26 1040660.0 220000.0 0.5 1.2433 0.9186 2077954 Maybridge3_005112 OCc1noc(n1)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I09 compound treatment 1840535.0 1140000.0 2.42 1191062.0 371000.0 0.84 2.3041 0.9006 1123605 Maybridge3_005113 CNc1nc(ns1)C2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I10 compound treatment 1605036.0 904000.0 1.92 1095126.0 275000.0 0.62 1.7969 0.8915 2077955 Maybridge3_005114 COc1cc(c(cn1)C(=O)N(C)c2ccc(Cl)cc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I11 compound treatment 1916907.0 1220000.0 2.58 1252087.0 432000.0 0.98 2.5167 0.9125 2077956 Maybridge3_005115 Clc1ccc(Cn2ccnc2C(=O)c3ccccc3Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I12 compound treatment 1953691.0 1250000.0 2.66 1566961.0 747000.0 1.7 3.0781 0.9766 2077957 Maybridge3_005116 COc1cc(c(cn1)C(=O)Nc2cccc(C)c2C)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I13 compound treatment 1659515.0 958000.0 2.03 1301708.0 481000.0 1.09 2.2107 0.9579 2077958 Maybridge3_005117 CCSc1nc(C)nc(N)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I14 compound treatment 1301302.0 600000.0 1.27 1342020.0 522000.0 1.19 1.7385 0.9994 2077959 Maybridge3_005118 CC(C)Nc1cc(c(cn1)C(=O)Nc2c(C)cccc2C)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I15 compound treatment 1845837.0 1140000.0 2.43 1360294.0 540000.0 1.23 2.5842 0.9502 1088402 Maybridge3_005119 COC(=O)c1ccc(nc1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I16 compound treatment 1883783.0 1180000.0 2.51 1169529.0 349000.0 0.79 2.3344 0.8876 2077960 Maybridge3_005120 CCc1ccccc1n2nnnc2c3cnccc3C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I17 compound treatment 1366424.0 665000.0 1.41 1122092.0 302000.0 0.69 1.4826 0.9452 1639568 Maybridge3_005121 CC(C)(C)C(=O)N(Cc1cccs1)Cc2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I18 compound treatment 1597610.0 897000.0 1.9 1353684.0 533000.0 1.21 2.2014 0.9765 2077961 Maybridge3_005122 COc1nccc(c1C(=O)Nc2c(C)cccc2C)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I19 compound treatment 1438484.0 737000.0 1.56 1022606.0 202000.0 0.46 1.4306 0.878 1119880 Maybridge3_005123 CC(C)(C)C(=O)N(Cc1cccnc1)Cc2ccc(Cl)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I20 compound treatment 1340589.0 639000.0 1.36 1114904.0 295000.0 0.67 1.4323 0.9472 2077962 Maybridge3_005124 FC(F)(F)c1ccncc1C(=O)Oc2ccc(CC#N)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I21 compound treatment 1413017.0 712000.0 1.51 1134903.0 315000.0 0.72 1.573 0.9418 1092463 Maybridge3_005125 Nc1ccc(cc1)n2ccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I22 compound treatment 1316453.0 615000.0 1.3 1133386.0 313000.0 0.71 1.4258 0.9594 2077963 Maybridge3_005126 NC(=O)c1cccnc1OCC(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I23 mock treatment 1157874.0 457000.0 0.97 1088356.0 268000.0 0.61 1.1157 0.9751 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 I24 mock treatment 809956.0 109000.0 0.23 867672.0 47400.0 0.11 0.2394 0.9399 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J01 compound treatment 707711.0 6610.0 0.01 997569.0 177000.0 0.4 0.2949 0.7313 2077964 Maybridge3_005127 CC(C)C(=O)NCc1ccc(Cl)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J02 compound treatment 1048286.0 347000.0 0.74 1042691.0 222000.0 0.51 0.878 0.9832 1607458 Maybridge3_005128 Nc1cccc(F)c1c2nc(n[nH]2)c3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J03 compound treatment 1203242.0 502000.0 1.06 1223983.0 404000.0 0.92 1.4017 0.9973 2077965 Maybridge3_005129 Fc1ccc(NC(=O)c2c(Oc3ccccc3)nccc2C(F)(F)F)c(F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J04 compound treatment 1020647.0 320000.0 0.68 1145239.0 325000.0 0.74 1.0014 0.9991 1278612 Maybridge3_005130 Clc1ccc2c(Sc3nnc(NC(=O)C4CC4)s3)ccnc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J05 compound treatment 1129478.0 428000.0 0.91 1216574.0 396000.0 0.9 1.2793 1.0 2077966 Maybridge3_005131 Cc1ccccc1N/C(=N\O)/c2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J06 compound treatment 1373166.0 672000.0 1.42 1339567.0 519000.0 1.18 1.8423 0.9956 2077967 Maybridge3_005132 CSc1c(C#N)c(N)nc(SCc2ccc(C)cc2)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J07 compound treatment 1210238.0 509000.0 1.08 955488.0 135000.0 0.31 0.9806 0.8737 2077968 Maybridge3_005133 FC(F)(F)c1ccccc1c2noc(=O)n2c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J08 compound treatment 1362302.0 661000.0 1.4 1322860.0 503000.0 1.14 1.7991 0.9949 1058359 Maybridge3_005134 COc1ccc2ccccc2c1Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J09 compound treatment 1336152.0 635000.0 1.35 1404603.0 584000.0 1.33 1.8913 1.0 1395393 Maybridge3_005135 CCOC(=O)c1noc(Oc2ccc(Cl)cc2Cl)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J10 compound treatment 1188655.0 488000.0 1.03 1231730.0 411000.0 0.94 1.3923 0.9988 2077969 Maybridge3_005136 CS(=O)(=O)c1ncc(Cl)cn1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J11 compound treatment 1579771.0 879000.0 1.86 1099032.0 279000.0 0.63 1.7653 0.8972 2077970 Maybridge3_005137 COc1ccccc1n2c(C)coc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J12 compound treatment 1502176.0 801000.0 1.7 1740777.0 920000.0 2.09 2.6807 0.9946 2077971 Maybridge3_005138 Cc1cc(ccc1NC(=O)c2cccs2)c3nnc(o3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J13 compound treatment 1701890.0 1000000.0 2.12 1885204.0 1060000.0 2.42 3.2122 0.9978 1719948 Maybridge3_005139 CSc1ccncc1C(=O)Nc2ccc(F)cc2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J14 compound treatment 1634063.0 933000.0 1.98 1683672.0 863000.0 1.96 2.7866 1.0 1123701 Maybridge3_005140 OC1(Cc2ccncc2)C(=O)Nc3ccc(F)cc31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J15 compound treatment 1992422.0 1290000.0 2.74 1555696.0 735000.0 1.67 3.118 0.972 2077972 Maybridge3_005141 Clc1ccc(cc1)C(=O)CC(C(=O)c2cccnc2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J16 compound treatment 1677649.0 977000.0 2.07 1624588.0 804000.0 1.83 2.7569 0.9981 1421742 Maybridge3_005142 CCOC(=O)c1csc(NC(=O)CSc2cc(Cl)ccc2Cl)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J17 compound treatment 1607564.0 906000.0 1.92 1696147.0 876000.0 1.99 2.7669 0.9998 1524229 Maybridge3_005143 OCCSc1nc2n(ncc2c(=O)[nH]1)c3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J18 compound treatment 1566906.0 866000.0 1.84 1488158.0 668000.0 1.52 2.3716 0.9956 2077973 Maybridge3_005144 CN(C(=O)CSc1nc(C2CCCCC2)c(C#N)c(=O)[nH]1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J19 compound treatment 1330727.0 630000.0 1.33 1261208.0 441000.0 1.0 1.6527 0.99 2077974 Maybridge3_005145 FC(F)(F)c1cccc(Oc2ccc3nnc(c4ccccc4)n3n2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J20 compound treatment 1201164.0 500000.0 1.06 1116330.0 296000.0 0.67 1.2256 0.976 1509284 Maybridge3_005146 CNC(C)CN1c2ccccc2Sc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J21 compound treatment 1232244.0 531000.0 1.13 1225932.0 406000.0 0.92 1.4483 0.9951 2077975 Maybridge3_005147 Fc1ccc(COc2ncnc3cc(Cl)ccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J22 compound treatment 1014315.0 313000.0 0.66 1205640.0 385000.0 0.88 1.089 0.9906 1344604 Maybridge3_005148 C1Cc2ccccc2C(N1)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J23 mock treatment 1161806.0 461000.0 0.98 1168711.0 348000.0 0.79 1.2508 0.9946 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 J24 mock treatment 607857.0 -93200.0 -0.2 738405.0 -81900.0 -0.19 -0.2714 -0.9995 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K01 compound treatment 833621.0 133000.0 0.28 843868.0 23600.0 0.05 0.2366 0.8272 2077976 Maybridge3_005149 CCNC(=O)Oc1noc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K02 compound treatment 1028219.0 327000.0 0.69 1092836.0 273000.0 0.62 0.9285 0.9984 2077977 Maybridge3_005150 CN(C(=O)c1cnccc1C(F)(F)F)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K03 compound treatment 1073727.0 373000.0 0.79 1192504.0 372000.0 0.85 1.157 0.9994 1171341 Maybridge3_005151 CC(=O)Nc1ccc(cc1N)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K04 compound treatment 1076329.0 375000.0 0.8 1183332.0 363000.0 0.83 1.1461 0.9998 2077978 Maybridge3_005152 CSc1nc(nc(N)c1C#N)c2ccc(cc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K05 compound treatment 1222828.0 522000.0 1.11 1196189.0 376000.0 0.85 1.3864 0.9919 1425442 Maybridge3_005153 NC(=O)c1ccc(OCc2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K06 compound treatment 1298133.0 597000.0 1.27 1237502.0 417000.0 0.95 1.5657 0.9899 2077979 Maybridge3_005154 FC(F)(F)c1ccncc1c2noc(n2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K07 compound treatment 1262898.0 562000.0 1.19 1485205.0 665000.0 1.51 1.9111 0.993 2077980 Maybridge3_005155 CCOC(=O)c1cc(no1)c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K08 compound treatment 1275419.0 574000.0 1.22 1212816.0 393000.0 0.89 1.492 0.9883 2077981 Maybridge3_005156 Clc1ccc(NC(=O)OCc2noc(n2)c3cccs3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K09 compound treatment 1445057.0 744000.0 1.58 1310531.0 490000.0 1.11 1.9034 0.9856 2077982 Maybridge3_005157 Nc1n[nH]c(NCc2ccco2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K10 compound treatment 1628483.0 927000.0 1.97 1400498.0 580000.0 1.32 2.323 0.9812 2077983 Maybridge3_005158 CCOc1cc(c(cn1)C(=O)NCc2ccc(Cl)cc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K11 compound treatment 1583781.0 883000.0 1.87 1724772.0 904000.0 2.06 2.7773 0.9989 2077984 Maybridge3_005159 CCOC(=O)/C(=C/1\SCC(C)(O)N1c2c(F)cccc2F)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K12 compound treatment 1551480.0 850000.0 1.8 1419488.0 599000.0 1.36 2.2381 0.9905 2077985 Maybridge3_005160 CSc1cc(c(cn1)C(=O)Nc2cccc(C)c2C)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K13 compound treatment 1547716.0 847000.0 1.79 1291212.0 471000.0 1.07 2.0262 0.9695 1444169 Maybridge3_005161 CSc1nc(N)nc(n1)N2CCSCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K14 compound treatment 1692958.0 992000.0 2.1 1175856.0 356000.0 0.81 2.0585 0.9138 2077986 Maybridge3_005162 CCN(C(=O)c1cnc(SC)cc1C(F)(F)F)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K15 compound treatment 1857808.0 1160000.0 2.45 985204.0 165000.0 0.37 1.9991 0.8059 2077987 Maybridge3_005163 Cc1ccc(cc1)c2csc(CO)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K16 compound treatment 1602411.0 901000.0 1.91 1369360.0 549000.0 1.25 2.2338 0.9787 2077988 Maybridge3_005164 FC(F)(F)c1ccc(cc1)n2nnnc2c3cnccc3C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K17 compound treatment 1551258.0 850000.0 1.8 1541949.0 722000.0 1.64 2.4346 0.9989 2077989 Maybridge3_005165 CC(=O)OCC(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K18 compound treatment 1543386.0 842000.0 1.79 1323252.0 503000.0 1.14 2.0712 0.9768 2077990 Maybridge3_005166 CCSc1nccc(c1C(=O)Nc2c(C)cccc2C)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K19 compound treatment 1360874.0 660000.0 1.4 1364511.0 544000.0 1.24 1.864 0.9981 1095724 Maybridge3_005167 CSc1nc(O)cc(n1)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K20 compound treatment 1308520.0 607000.0 1.29 1226887.0 407000.0 0.92 1.5642 0.9868 1436142 Maybridge3_005168 O=C(Oc1ccc(CC#N)cc1)c2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K21 compound treatment 1301000.0 600000.0 1.27 1190901.0 371000.0 0.84 1.4951 0.98 2077991 Maybridge3_005169 CC(=O)Nc1c(Cl)cc(Cl)c2cccnc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K22 compound treatment 1019241.0 318000.0 0.67 1148407.0 328000.0 0.75 1.0044 0.9987 2077992 Maybridge3_005170 FC(F)(F)COc1ncccc1C(=O)Nc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K23 mock treatment 1140450.0 439000.0 0.93 1066591.0 246000.0 0.56 1.0546 0.9704 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 K24 mock treatment 948662.0 248000.0 0.52 843708.0 23400.0 0.05 0.4088 0.7749 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L01 compound treatment 602903.0 -98200.0 -0.21 780115.0 -40200.0 -0.09 -0.2118 -0.9316 2077993 Maybridge3_005171 CCOC(=O)c1n[nH]cc1c2ccc(Cl)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L02 compound treatment 942450.0 241000.0 0.51 1030839.0 211000.0 0.48 0.7003 0.9994 1396790 Maybridge3_005172 COc1ccc(CNC(=O)CSc2nc3cccnc3s2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L03 compound treatment 1071115.0 370000.0 0.78 1081051.0 261000.0 0.59 0.9739 0.9905 2077994 Maybridge3_005173 Cc1cccc(N/C(=N\O)/c2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L04 compound treatment 1043785.0 343000.0 0.73 1190529.0 370000.0 0.84 1.1089 0.9973 2077995 Maybridge3_005174 Clc1ccc2c(Sc3nnc(NC(=O)c4cccs4)s3)ccnc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L05 compound treatment 1259734.0 559000.0 1.18 1151231.0 331000.0 0.75 1.3695 0.976 2077996 Maybridge3_005175 O/N=C(\Nc1ccccc1C(F)(F)F)/c2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L06 compound treatment 1267064.0 566000.0 1.2 1435717.0 615000.0 1.4 1.8378 0.9971 2077997 Maybridge3_005176 CSc1c(C#N)c(N)nc(SCc2ccc(F)c(F)c2)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L07 compound treatment 1293892.0 593000.0 1.26 1336844.0 517000.0 1.17 1.7191 0.9994 2077998 Maybridge3_005177 Cc1ccc(N/C(=N/O)/c2cnccc2C(F)(F)F)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L08 compound treatment 1256224.0 555000.0 1.18 1268519.0 448000.0 1.02 1.5528 0.9974 1083641 Maybridge3_005178 CCOc1nc(N)c(C#N)c(c1C#N)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L09 compound treatment 1407982.0 707000.0 1.5 1312206.0 492000.0 1.12 1.8505 0.9896 2077999 Maybridge3_005179 Clc1cccc(c1)c2nnc(o2)c3ccno3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L10 compound treatment 1484104.0 783000.0 1.66 1539682.0 719000.0 1.64 2.3303 1.0 1066693 Maybridge3_005180 OC(=O)Cc1ccc(OCc2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L11 compound treatment 1692540.0 991000.0 2.1 1357928.0 538000.0 1.22 2.3506 0.9667 2078000 Maybridge3_005181 Clc1ccccc1CN2C(=C)COC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L12 compound treatment 1668741.0 968000.0 2.05 1498706.0 678000.0 1.54 2.5412 0.9901 1345520 Maybridge3_005182 COC(=O)C1=C(C)NC(=O)CC1c2ccc(cc2)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L13 compound treatment 1746271.0 1050000.0 2.22 1553993.0 734000.0 1.67 2.7463 0.9902 2078001 Maybridge3_005183 COc1ccncc1C(=O)Nc2ccc(F)cc2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L14 compound treatment 1579024.0 878000.0 1.86 1399750.0 579000.0 1.32 2.2476 0.9857 2078002 Maybridge3_005184 OC(=O)CC1=Nn2c(nnc2SC1)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L15 compound treatment 1519066.0 818000.0 1.73 1347719.0 527000.0 1.2 2.0741 0.9838 2078003 Maybridge3_005185 Clc1ccc(cc1)C(=O)CC(C(=O)c2cccnc2)c3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L16 compound treatment 1786623.0 1090000.0 2.3 1288707.0 468000.0 1.06 2.3803 0.9387 1718647 Maybridge3_005186 COC(=O)C1=C(C)Nc2[nH]ncc2C1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L17 compound treatment 99450.0 -602000.0 -1.28 95636.0 -725000.0 -1.65 -2.0669 -0.992 2078004 Maybridge3_005187 CCOC(=O)c1ccc2nc(N/C=N/O)sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L18 compound treatment 1491201.0 790000.0 1.67 1358088.0 538000.0 1.22 2.049 0.988 2078005 Maybridge3_005188 CCC/1(CCCC\C1=N/O)c2cccc(OC)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L19 compound treatment 1346876.0 646000.0 1.37 1311088.0 491000.0 1.12 1.7571 0.9949 2078006 Maybridge3_005189 Fc1ccc(Oc2ccc3nnc(c4ccccc4)n3n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L20 compound treatment 1268636.0 568000.0 1.2 1532484.0 712000.0 1.62 1.9957 0.9893 1680891 Maybridge3_005190 OC1N=C(c2cccc(O)c2)c3cc(Cl)ccc3NC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L21 compound treatment 1159643.0 459000.0 0.97 1352519.0 532000.0 1.21 1.543 0.9941 2078007 Maybridge3_005191 Cc1ccccc1COc2ncnc3cc(Cl)ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L22 compound treatment 922406.0 221000.0 0.47 1224951.0 405000.0 0.92 0.9823 0.9512 1317921 Maybridge3_005192 CC(C)N(CCO)S(=O)(=O)c1ccc(N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L23 mock treatment 780831.0 79700.0 0.17 1169555.0 349000.0 0.79 0.681 0.8388 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 L24 mock treatment 500099.0 -201000.0 -0.43 851871.0 31600.0 0.07 -0.2505 -0.5797 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M01 compound treatment 608769.0 -92300.0 -0.2 707802.0 -112000.0 -0.26 -0.3192 -0.9913 1432157 Maybridge3_005193 CC(C)NC(=O)Oc1noc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M02 compound treatment 1272977.0 572000.0 1.21 971841.0 152000.0 0.34 1.1009 0.8735 2078008 Maybridge3_005194 CCN(C(=O)c1cnccc1C(F)(F)F)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M03 compound treatment 1155439.0 454000.0 0.96 1121654.0 301000.0 0.69 1.1656 0.9861 2078009 Maybridge3_005195 CC(=O)Nc1cccc(c1)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M04 compound treatment 1149338.0 448000.0 0.95 1171579.0 351000.0 0.8 1.2367 0.9963 2078010 Maybridge3_005196 FC(F)(F)c1ccncc1c2nnc(o2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M05 compound treatment 1193444.0 492000.0 1.04 1254903.0 435000.0 0.99 1.4368 0.9996 2078011 Maybridge3_005197 Oc1cc(nc(n1)c2cccs2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M06 compound treatment 1328856.0 628000.0 1.33 1356616.0 536000.0 1.22 1.8033 0.999 2078012 Maybridge3_005198 Cn1cc(Cl)c(n1)c2noc(n2)c3ccccc3C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M07 compound treatment 1455388.0 754000.0 1.6 1243676.0 423000.0 0.96 1.8114 0.9705 2078013 Maybridge3_005199 Fc1cccc(F)c1C(=O)CSC(=S)N2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M08 compound treatment 1361007.0 660000.0 1.4 1269435.0 449000.0 1.02 1.7113 0.988 2078014 Maybridge3_005200 Cc1nc(C(=O)NCC(=O)c2cccc(Cl)c2)c(o1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M09 compound treatment 1367627.0 667000.0 1.41 1407994.0 588000.0 1.34 1.944 0.9996 1097098 Maybridge3_005201 O=c1oc(ns1)c2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M10 compound treatment 1186438.0 485000.0 1.03 1492472.0 672000.0 1.53 1.8082 0.9815 2078015 Maybridge3_005202 CCOc1cc(c(cn1)C(=O)N(CC)Cc2ccc(Cl)cc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M11 compound treatment 1533313.0 832000.0 1.76 1625383.0 805000.0 1.83 2.5418 0.9998 1461277 Maybridge3_005203 CC(C)Nc1nc(cs1)c2c(F)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M12 compound treatment 1595737.0 895000.0 1.9 1694515.0 874000.0 1.99 2.7466 0.9997 2078016 Maybridge3_005204 CCc1cccc(CC)c1N(C)C(=O)c2cnccc2C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M13 compound treatment 1536216.0 835000.0 1.77 1649426.0 829000.0 1.89 2.5848 0.9995 1633709 Maybridge3_005205 CSc1nc(N)nc(n1)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M14 compound treatment 1557453.0 856000.0 1.82 1497846.0 678000.0 1.54 2.373 0.9967 2078017 Maybridge3_005206 COC(=O)CSc1cc(c(cn1)C(=O)Nc2ccc(Cl)cc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M15 compound treatment 1669780.0 969000.0 2.05 1520077.0 700000.0 1.59 2.5771 0.992 2078018 Maybridge3_005207 OCc1nc(cs1)c2ccc(Cl)c(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M16 compound treatment 1575895.0 875000.0 1.85 1378502.0 558000.0 1.27 2.2088 0.9829 2078019 Maybridge3_005208 NC(=O)c1cnc(cc1C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M17 compound treatment 1535204.0 834000.0 1.77 1636799.0 817000.0 1.86 2.563 0.9997 2078020 Maybridge3_005209 CC(=O)OCC(=O)c1ccc(cc1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M18 compound treatment 1568318.0 867000.0 1.84 1381113.0 561000.0 1.28 2.2016 0.984 2078021 Maybridge3_005210 CNc1nccc(c1C(=O)Nc2c(C)cccc2C)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M19 compound treatment 1245796.0 545000.0 1.15 1572701.0 752000.0 1.71 2.0261 0.9817 1614933 Maybridge3_005211 OC(=O)c1ccccc1C(=O)N(Cc2cccnc2)Cc3ccc(Cl)cc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M20 compound treatment 1567704.0 867000.0 1.84 1470701.0 650000.0 1.48 2.3447 0.9942 2078022 Maybridge3_005212 COC(=O)c1cnc(Oc2ccc(N)cc2)cc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M21 compound treatment 1520437.0 819000.0 1.74 1221694.0 401000.0 0.91 1.8735 0.9549 2078023 Maybridge3_005213 Oc1c2CSCCc2nn1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M22 compound treatment 1066212.0 365000.0 0.77 1003810.0 184000.0 0.42 0.8424 0.958 2078024 Maybridge3_005214 CCN(C(=O)c1cccnc1OCC(F)(F)F)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M23 mock treatment 1083152.0 382000.0 0.81 1018230.0 198000.0 0.45 0.8909 0.9615 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 M24 mock treatment 552730.0 -148000.0 -0.31 816130.0 -4150.0 -0.01 -0.2291 -0.728 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N01 compound treatment 573811.0 -127000.0 -0.27 769663.0 -50600.0 -0.12 -0.2722 -0.9278 1463277 Maybridge3_005215 CSc1[nH]nc(c1SC(=O)N(C)C)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N02 compound treatment 1207822.0 507000.0 1.07 1105057.0 285000.0 0.65 1.2174 0.9706 1460875 Maybridge3_005216 COc1cccc(CNC(=O)CSc2nc3cccnc3s2)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N03 compound treatment 1274381.0 573000.0 1.22 1305744.0 485000.0 1.1 1.6398 0.9988 2078025 Maybridge3_005217 O/N=C(\Nc1cccc(c1)C(F)(F)F)/c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N04 compound treatment 1123368.0 422000.0 0.9 1465190.0 645000.0 1.47 1.6698 0.972 1529579 Maybridge3_005218 CC(=O)N1CCc2cccc(N)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N05 compound treatment 1359349.0 658000.0 1.4 1409007.0 589000.0 1.34 1.9332 0.9998 1247459 Maybridge3_005219 Cc1ccccc1n2c(noc2=O)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N06 compound treatment 1424258.0 723000.0 1.53 1409612.0 589000.0 1.34 2.0315 0.9977 2078026 Maybridge3_005220 CSc1c(C#N)c(N)nc(SCC(=O)c2ccccc2)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N07 compound treatment 1355953.0 655000.0 1.39 1262416.0 442000.0 1.01 1.6924 0.9874 2078027 Maybridge3_005221 O/N=C(\Nc1ccc(Cl)cc1Cl)/c2cnccc2C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N08 compound treatment 1198272.0 497000.0 1.05 1381902.0 562000.0 1.28 1.6482 0.9955 2078028 Maybridge3_005222 CC(C)(C)C1NC(CS1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N09 compound treatment 1298601.0 598000.0 1.27 1378707.0 558000.0 1.27 1.7934 1.0 2078029 Maybridge3_005223 Clc1cccc(Cl)c1c2noc(n2)c3ccno3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N10 compound treatment 1313428.0 612000.0 1.3 1370042.0 550000.0 1.25 1.8017 0.9998 1681856 Maybridge3_005224 Cc1nn(c2ccccc2)c3[nH]c4ccccc4c(=O)c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N11 compound treatment 1368050.0 667000.0 1.41 1418763.0 598000.0 1.36 1.9619 0.9998 2078030 Maybridge3_005225 COc1cccc(OC)c1CNC(=O)c2cnccc2C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N12 compound treatment 1268032.0 567000.0 1.2 1721455.0 901000.0 2.05 2.2986 0.9677 2078031 Maybridge3_005226 CCC(=O)Nc1ccc(cc1C)c2nnc(o2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N13 compound treatment 1198752.0 498000.0 1.06 1368931.0 549000.0 1.25 1.628 0.9965 1032913 Maybridge3_005227 Clc1ccccc1C2CC(=O)c3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N14 compound treatment 1214139.0 513000.0 1.09 1406907.0 587000.0 1.33 1.7122 0.9949 1479452 Maybridge3_005228 CCOC(=O)c1c(C)n(C2CC2)c3ccc(OC)cc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N15 compound treatment 1332141.0 631000.0 1.34 1382378.0 562000.0 1.28 1.8496 0.9997 2078032 Maybridge3_005229 O=C/1NC(=N\C1=C\c2cccs2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N16 compound treatment 1340049.0 639000.0 1.35 1266932.0 447000.0 1.02 1.6759 0.9899 2078033 Maybridge3_005230 CO/C=N/c1nc-2c(CCc3ccccc23)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N17 compound treatment 1267036.0 566000.0 1.2 1370924.0 551000.0 1.25 1.7336 0.9998 2078034 Maybridge3_005231 CCOC(=O)CSc1nc2c(C)ccc(F)c2cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N18 compound treatment 1199268.0 498000.0 1.06 1614568.0 794000.0 1.81 2.0237 0.9674 1491062 Maybridge3_005232 NC(=O)c1ccccc1OCC2CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N19 compound treatment 1256803.0 556000.0 1.18 1370719.0 550000.0 1.25 1.7179 0.9995 1535120 Maybridge3_005233 Oc1c(C2CCCCC2)c(=O)n3CCCc4cccc1c43 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N20 compound treatment 1219468.0 518000.0 1.1 1233075.0 413000.0 0.94 1.4407 0.9969 1174232 Maybridge3_005234 CC1(C)C2CCC1(C)C(C2)N3CCNCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N21 compound treatment 1541163.0 840000.0 1.78 1324091.0 504000.0 1.15 2.0692 0.9772 1352902 Maybridge3_005235 Cc1ccc2ncnc(Oc3ncccc3N)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N22 compound treatment 1151575.0 450000.0 0.95 1299059.0 479000.0 1.09 1.445 0.9979 2078035 Maybridge3_005236 CN(C1CCN2CCc3ccccc3C2C1)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N23 mock treatment 959684.0 259000.0 0.55 1156716.0 336000.0 0.76 0.9285 0.9867 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 N24 mock treatment 556868.0 -144000.0 -0.31 866486.0 46200.0 0.11 -0.1419 -0.439 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O01 compound treatment 471539.0 -230000.0 -0.49 531855.0 -288000.0 -0.66 -0.8078 -0.9892 2078036 Maybridge3_005237 Cc1cc(C)c2c(=O)c(coc2c1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O02 compound treatment 1346875.0 646000.0 1.37 1052273.0 232000.0 0.53 1.341 0.914 2078037 Maybridge3_005238 CCOc1cccc(NC(=O)c2cnccc2C(F)(F)F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O03 compound treatment 1190676.0 490000.0 1.04 1224880.0 405000.0 0.92 1.3843 0.9982 2078038 Maybridge3_005239 CC(CC#N)C(=O)c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O04 compound treatment 1391142.0 690000.0 1.46 1319188.0 499000.0 1.13 1.8365 0.9921 2078039 Maybridge3_005240 CC(C)(C)c1nnc(o1)c2cnccc2C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O05 compound treatment 1500933.0 800000.0 1.7 1284892.0 465000.0 1.06 1.9459 0.9741 2078040 Maybridge3_005241 OCc1cc(no1)c2ccc(Cl)c(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O06 compound treatment 1629523.0 928000.0 1.97 1295038.0 475000.0 1.08 2.155 0.96 2078041 Maybridge3_005242 CCOC(=O)c1cc(n[nH]1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O07 compound treatment 1492219.0 791000.0 1.68 1267299.0 447000.0 1.02 1.9046 0.9712 1238161 Maybridge3_005243 Clc1ccc(cc1)C(=O)CSC(=S)N2CCSCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O08 compound treatment 1476368.0 775000.0 1.64 1276721.0 456000.0 1.04 1.896 0.9754 1575872 Maybridge3_005244 CC(C)(OC(=O)Nc1ccc(Cl)cc1)C#Cc2cncnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O09 compound treatment 1480625.0 780000.0 1.65 1265621.0 445000.0 1.01 1.8845 0.9724 2078042 Maybridge3_005245 O=c1oc(ns1)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O10 compound treatment 1251266.0 550000.0 1.17 1266505.0 446000.0 1.01 1.5421 0.9976 2078043 Maybridge3_005246 COc1cc(c(cn1)C(=O)N(C)Cc2cc(Cl)cc(Cl)c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O11 compound treatment 1421459.0 720000.0 1.53 1219232.0 399000.0 0.91 1.7212 0.9691 2078044 Maybridge3_005247 Clc1ccc(cc1)C(=O)NCC#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O12 compound treatment 1608398.0 907000.0 1.92 1171780.0 352000.0 0.8 1.9252 0.9243 2078045 Maybridge3_005248 CN(C(=O)c1cnccc1C(F)(F)F)c2cccc(C)c2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O13 compound treatment 1599188.0 898000.0 1.9 1182111.0 362000.0 0.82 1.928 0.9296 1663601 Maybridge3_005249 CC(C)c1nc(N)nc(O)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O14 compound treatment 1577761.0 877000.0 1.86 1101693.0 281000.0 0.64 1.7666 0.8988 2078046 Maybridge3_005250 CCN(C(=O)c1cnc(NC(C)C)cc1C(F)(F)F)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O15 compound treatment 1629800.0 929000.0 1.97 1155315.0 335000.0 0.76 1.9308 0.9146 2078047 Maybridge3_005251 Cc1cc(/N=C/c2cccnc2)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O16 compound treatment 1713098.0 1010000.0 2.15 1234518.0 414000.0 0.94 2.183 0.9317 2078048 Maybridge3_005252 FC(F)(F)c1ccccc1n2nnnc2c3ccc(Cl)cc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O17 compound treatment 1624372.0 923000.0 1.96 1055965.0 236000.0 0.54 1.7629 0.8687 2078049 Maybridge3_005253 CC(C)(C)C(=O)OCC(=O)c1ccc(cc1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O18 compound treatment 1736464.0 1040000.0 2.19 1066622.0 246000.0 0.56 1.9481 0.86 2078050 Maybridge3_005254 CN(C)CCSc1nccc(c1C(=O)Nc2c(C)cccc2C)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O19 compound treatment 1678234.0 977000.0 2.07 1186582.0 366000.0 0.83 2.0536 0.9198 1255779 Maybridge3_005255 CC1=CCC(C(C1)C(=O)O)C(=O)N(Cc2cccnc2)Cc3ccc(Cl)cc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O20 compound treatment 1952287.0 1250000.0 2.65 1275636.0 455000.0 1.04 2.6076 0.9158 2078051 Maybridge3_005256 COc1ccc(/C=C(\C#N)/S(=O)(=O)c2ccc(cn2)C(F)(F)F)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O21 compound treatment 1812639.0 1110000.0 2.36 1249872.0 430000.0 0.98 2.3569 0.924 1361645 Maybridge3_005257 Oc1nc(nc2CCSCc12)C3CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O22 compound treatment 1408968.0 708000.0 1.5 1078336.0 258000.0 0.59 1.476 0.916 2078052 Maybridge3_005258 CC1OC(=O)N(C1=O)c2cc(Cl)cc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O23 mock treatment 1338626.0 638000.0 1.35 1014991.0 195000.0 0.44 1.2687 0.8921 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 O24 mock treatment 558283.0 -143000.0 -0.3 650760.0 -170000.0 -0.39 -0.4866 -0.9929 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P01 compound treatment 384160.0 -317000.0 -0.67 504027.0 -316000.0 -0.72 -0.9835 -0.9994 2078053 Maybridge3_005259 CNC(=O)Sc1c(SC)n(nc1c2ccc(Cl)cc2)C(=O)NC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P02 compound treatment 526974.0 -174000.0 -0.37 781344.0 -38900.0 -0.09 -0.3236 -0.8525 1629161 Maybridge3_005260 CCOC(=O)c1cnc2cc(Cl)c(F)cc2c1OCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P03 compound treatment 1079166.0 378000.0 0.8 953632.0 133000.0 0.3 0.7811 0.9115 2078054 Maybridge3_005261 O/N=C(\Nc1ccc(cc1)C(F)(F)F)/c2c(F)cccc2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P04 compound treatment 934418.0 233000.0 0.49 872260.0 52000.0 0.12 0.4333 0.8521 1350307 Maybridge3_005262 COC(=O)C1(C)Oc2cc(Cl)ccc2NC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P05 compound treatment 1095258.0 394000.0 0.84 1123344.0 303000.0 0.69 1.0781 0.9954 2078055 Maybridge3_005263 FC(F)(F)c1ccccc1n2c(noc2=O)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P06 compound treatment 1063055.0 362000.0 0.77 1084984.0 265000.0 0.6 0.9681 0.9928 1605723 Maybridge3_005264 CSc1c(C#N)c(N)nc2sc(C(=O)c3ccc(F)c(F)c3)c(N)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P07 compound treatment 793758.0 92700.0 0.2 853287.0 33000.0 0.08 0.192 0.9129 2078056 Maybridge3_005265 FC(F)(F)c1ccncc1c2noc(=O)n2c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P08 compound treatment 788995.0 87900.0 0.19 950251.0 130000.0 0.3 0.3407 0.9753 2078057 Maybridge3_005266 Cc1ccc(cc1)c2nn[nH]n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P09 compound treatment 774449.0 73400.0 0.16 790263.0 -30000.0 -0.07 0.0617 0.3633 2078058 Maybridge3_005267 FC(F)(F)c1ccc(cc1)c2noc(n2)c3ccno3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P10 compound treatment 677245.0 -23900.0 -0.05 790150.0 -30100.0 -0.07 -0.0842 -0.9888 1465285 Maybridge3_005268 COc1ccc(cc1)n2nc(C)cc2Nc3ccccc3C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P11 compound treatment 725362.0 24300.0 0.05 732498.0 -87800.0 -0.2 -0.1047 -0.5083 2078059 Maybridge3_005269 Clc1ccc(Cn2ncc(Br)c2C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P12 compound treatment 749978.0 48900.0 0.1 690585.0 -130000.0 -0.29 -0.1352 -0.4327 1728956 Maybridge3_005270 C(N1CCCCC1)c2csc(Nc3ccccc3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P13 compound treatment 537601.0 -163000.0 -0.35 484000.0 -336000.0 -0.76 -0.7857 -0.936 2078060 Maybridge3_005271 Oc1ccccc1c2cc(n[nH]2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P14 compound treatment 868604.0 168000.0 0.36 859594.0 39300.0 0.09 0.3143 0.8583 2078061 Maybridge3_005272 CN(C(=O)C)c1cccnc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P15 compound treatment 1042321.0 341000.0 0.72 945935.0 126000.0 0.29 0.7135 0.9174 1575180 Maybridge3_005273 CC(C)(Oc1ccc(C#N)cc1)C(=O)Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P16 compound treatment 944042.0 243000.0 0.52 994853.0 175000.0 0.4 0.6448 0.9917 1266077 Maybridge3_005274 CC(=O)Nc1nc-2c(Cc3ccccc23)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P17 compound treatment 959924.0 259000.0 0.55 836089.0 15800.0 0.04 0.4134 0.7518 2078062 Maybridge3_005275 Clc1ccc(Sc2ccc3nnc(c4ccccc4)n3n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P18 compound treatment 906687.0 206000.0 0.44 877098.0 56800.0 0.13 0.3995 0.8789 1141653 Maybridge3_005276 Cc1c(OCC(=O)NCC=C)ccc2C(=O)CC(C)(C)Oc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P19 compound treatment 1024054.0 323000.0 0.68 955614.0 135000.0 0.31 0.7017 0.9348 2078063 Maybridge3_005277 Cc1ccc(Oc2ccc3nnc(c4ccccc4)n3n2)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P20 compound treatment 1004685.0 304000.0 0.64 976775.0 156000.0 0.36 0.7067 0.961 2078064 Maybridge3_005278 COc1cccc(c1)C/2CCCC\C2=N\O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P21 compound treatment 888039.0 187000.0 0.4 759172.0 -61100.0 -0.14 0.182 0.4334 1642742 Maybridge3_005279 CC(=O)Nc1ccc(F)c(C#N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P22 compound treatment 513548.0 -188000.0 -0.4 659442.0 -161000.0 -0.37 -0.5397 -0.9991 1258357 Maybridge3_005280 Cc1ccc(OCC(=O)O)c2CCCc21 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P23 mock treatment 534948.0 -166000.0 -0.35 644874.0 -175000.0 -0.4 -0.5311 -0.9981 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1445 P24 mock treatment 410996.0 -290000.0 -0.62 539364.0 -281000.0 -0.64 -0.8865 -0.9998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A01 compound treatment 393524.0 -365000.0 -0.77 400561.0 -402000.0 -0.91 -1.1939 -0.9966 1262176 Maybridge3_005281 CN1C=NC(O)(c2ccccc2)c3cc(Cl)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A02 compound treatment 490788.0 -268000.0 -0.57 427319.0 -375000.0 -0.85 -1.0051 -0.9806 2078065 Maybridge3_005282 CCC/C(=N\O)/c1ccccn1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A03 compound treatment 555424.0 -204000.0 -0.43 407095.0 -395000.0 -0.9 -0.9407 -0.9435 1178270 Maybridge3_005283 CCc1ccc(cc1)C(=O)Nc2cccnc2Oc3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A04 compound treatment 611459.0 -148000.0 -0.31 437900.0 -364000.0 -0.83 -0.8072 -0.9113 2078066 Maybridge3_005284 COc1ccc(cc1)c2ccc(OC)cc2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A05 compound treatment 630800.0 -128000.0 -0.27 581007.0 -221000.0 -0.5 -0.5481 -0.9582 1673293 Maybridge3_005285 COc1ccc(COc2cccnc2N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A06 compound treatment 638420.0 -121000.0 -0.26 695453.0 -107000.0 -0.24 -0.3527 -0.9997 1016235 Maybridge3_005286 O=c1cc(oc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A07 compound treatment 596556.0 -162000.0 -0.34 473670.0 -329000.0 -0.75 -0.772 -0.9381 1303077 Maybridge3_005287 Cc1ccc(Sc2ncccc2NC(=O)C(C)(C)C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A08 compound treatment 559798.0 -199000.0 -0.42 500493.0 -302000.0 -0.69 -0.784 -0.9728 1618605 Maybridge3_005288 COc1ccc(CC2(O)CCC3(CC2)OCCO3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A09 compound treatment 300087.0 -459000.0 -0.97 310673.0 -492000.0 -1.12 -1.4785 -0.9976 1474271 Maybridge3_005289 COc1ccc2nc(cc(NCCN(C)C)c2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A10 compound treatment 586500.0 -173000.0 -0.37 791953.0 -10400.0 -0.02 -0.2754 -0.7514 1914510 Maybridge3_005290 CN(S(=O)(=O)c1ccc(F)cc1)S(=O)(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A11 compound treatment 540312.0 -219000.0 -0.46 723553.0 -78800.0 -0.18 -0.4546 -0.9145 2078067 Maybridge3_005291 CCOC(=O)COc1nc(cc(c1C#N)C(F)(F)F)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A12 compound treatment 501817.0 -257000.0 -0.55 600739.0 -202000.0 -0.46 -0.7098 -0.9963 2078068 Maybridge3_005292 CC1CN=C(Nc2ccc(F)cc2F)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A13 compound treatment 712360.0 -46700.0 -0.1 1057712.0 255000.0 0.58 0.3405 0.5783 2078069 Maybridge3_005293 COc1nc(C)cc(c1C#N)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A14 compound treatment 660324.0 -98700.0 -0.21 767353.0 -35000.0 -0.08 -0.2043 -0.9125 2078070 Maybridge3_005294 CC1(C)NCSC1C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A15 compound treatment 622193.0 -137000.0 -0.29 776446.0 -26000.0 -0.06 -0.2468 -0.8339 2078071 Maybridge3_005295 CCOC(=O)c1csc(n1)n2cccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A16 compound treatment 554397.0 -205000.0 -0.43 500667.0 -302000.0 -0.69 -0.7918 -0.9756 1377776 Maybridge3_005296 COc1ccc(cc1)C(=O)NCC(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A17 compound treatment 552316.0 -207000.0 -0.44 609369.0 -193000.0 -0.44 -0.6202 -1.0 1368851 Maybridge3_005297 CC1(C)CC(=O)c2ccc(OCC#N)cc2O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A18 compound treatment 524597.0 -234000.0 -0.5 617609.0 -185000.0 -0.42 -0.6485 -0.9965 1919002 Maybridge3_005298 Fc1c(F)c(F)c(NS(=O)(=O)C2CCS(=O)(=O)C2)c(F)c1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A19 compound treatment 602473.0 -157000.0 -0.33 685247.0 -117000.0 -0.27 -0.423 -0.9941 2078072 Maybridge3_005299 CSc1cc(=O)c2ccccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A20 compound treatment 541906.0 -217000.0 -0.46 567049.0 -235000.0 -0.54 -0.7038 -0.9972 1698058 Maybridge3_005300 COC1OC(OC)C2C1C3CCC2C(O)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A21 compound treatment 488592.0 -270000.0 -0.57 550815.0 -252000.0 -0.57 -0.8098 -1.0 1385755 Maybridge3_005301 NCC(c1ccccc1)c2ccc3OCCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A22 compound treatment 460638.0 -298000.0 -0.63 489951.0 -312000.0 -0.71 -0.9496 -0.9983 2078073 Maybridge3_005302 Clc1ccc(OCCCN2CCN(CC2)c3cccc4[nH]ccc34)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A23 mock treatment 476384.0 -283000.0 -0.6 384899.0 -417000.0 -0.95 -1.0949 -0.9754 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 A24 mock treatment 435531.0 -323000.0 -0.69 427735.0 -375000.0 -0.85 -1.0872 -0.9942 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B01 compound treatment 449544.0 -309000.0 -0.66 465701.0 -337000.0 -0.77 -1.0052 -0.9971 1576065 Maybridge3_005303 O=C(C1CCCCC1)N2CCN(Cc3ccccc3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B02 compound treatment 601359.0 -158000.0 -0.33 967450.0 165000.0 0.38 0.029 0.0577 2078074 Maybridge3_005304 Oc1cc(nc(SCC(=O)c2ccc(Cl)cc2)n1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B03 compound treatment 895179.0 136000.0 0.29 1013293.0 211000.0 0.48 0.5431 0.9705 1029362 Maybridge3_005305 COC(=O)C(Cc1ccccc1)NC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B04 compound treatment 944986.0 186000.0 0.39 1027773.0 225000.0 0.51 0.6411 0.9916 2078075 Maybridge3_005306 CC[n+]1c(C)csc1Nc2ccc(cc2)N3CC(C)OC(C)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B05 compound treatment 1020136.0 261000.0 0.55 1038813.0 236000.0 0.54 0.7715 0.9999 1662988 Maybridge3_005307 Oc1nc(sc(=O)c1Cc2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B06 compound treatment 1114392.0 355000.0 0.75 1115671.0 313000.0 0.71 1.0363 0.9996 2078076 Maybridge3_005308 CCSc1nc(O)cc(n1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B07 compound treatment 842563.0 83500.0 0.18 1069399.0 267000.0 0.61 0.5545 0.8769 1683883 Maybridge3_005309 Oc1c(c2ccccc2)c(=O)[nH]c3cc(Cl)c(Cl)cc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B08 compound treatment 938176.0 179000.0 0.38 904668.0 102000.0 0.23 0.433 0.9723 1380299 Maybridge3_005310 Cc1cccc(Nc2ncnc(N)n2)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B09 compound treatment 1013945.0 255000.0 0.54 1070122.0 268000.0 0.61 0.8125 0.9982 1691877 Maybridge3_005311 CN(C)CCNc1cc(nc2ccccc12)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B10 compound treatment 1046840.0 288000.0 0.61 1370340.0 568000.0 1.29 1.3445 0.9414 2078077 Maybridge3_005312 FC(F)(F)c1cccc(Nc2ncnc(n2)n3cccc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B11 compound treatment 990927.0 232000.0 0.49 1178917.0 377000.0 0.86 0.9529 0.9653 1405740 Maybridge3_005313 CC(Cc1ccccc1)(Nc2ccc(Cl)cc2)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B12 compound treatment 1011743.0 253000.0 0.54 1116681.0 314000.0 0.71 0.8841 0.9899 2078078 Maybridge3_005314 Nc1nc(N)nc(n1)c2ccccc2C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B13 compound treatment 1031422.0 272000.0 0.58 1062106.0 260000.0 0.59 0.8259 0.9999 1151988 Maybridge3_005315 CCCC1C(NC(CC1=O)c2ccco2)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B14 compound treatment 1033770.0 275000.0 0.58 1093466.0 291000.0 0.66 0.8798 0.998 1733095 Maybridge3_005316 COCc1cc(=O)oc2cc(NS(=O)(=O)C)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B15 compound treatment 786112.0 27100.0 0.06 848882.0 46500.0 0.11 0.1153 0.9589 2078079 Maybridge3_005317 CCc1nc2cccc3cccc([nH]1)c32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B16 compound treatment 910706.0 152000.0 0.32 1027987.0 226000.0 0.51 0.59 0.9747 2078080 Maybridge3_005318 COc1cc(/C=N/c2ccc(Cl)cc2)ccc1OC(=O)C3CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B17 compound treatment 915039.0 156000.0 0.33 1050164.0 248000.0 0.56 0.6322 0.9678 2078081 Maybridge3_005319 NC(=O)c1ccccc1OCCCN2CCN(CC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B18 compound treatment 1056213.0 297000.0 0.63 1133100.0 331000.0 0.75 0.9772 0.9961 1520180 Maybridge3_005320 Cc1cc(O)nc(NC(=O)C(C)(C)C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B19 compound treatment 1167935.0 409000.0 0.87 1218265.0 416000.0 0.95 1.2815 0.9991 2078082 Maybridge3_005321 Nc1nnc(o1)c2cn(nc2c3ccc(Cl)cc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B20 compound treatment 1118469.0 359000.0 0.76 1146239.0 344000.0 0.78 1.0916 0.9999 2078083 Maybridge3_005322 CCCc1nc(SC)nc(O)c1CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B21 compound treatment 1144923.0 386000.0 0.82 1031907.0 230000.0 0.52 0.9474 0.9764 1160001 Maybridge3_005323 O=C(Oc1cc(=O)n2CCCc3cccc1c32)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B22 compound treatment 1088159.0 329000.0 0.7 1103528.0 301000.0 0.68 0.9775 1.0 2078084 Maybridge3_005324 FC(F)(F)c1cccc(c1)N(C(=O)c2ccco2)C3=NCCCC(=O)S3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B23 mock treatment 719867.0 -39200.0 -0.08 661908.0 -140000.0 -0.32 -0.2846 -0.8622 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 B24 mock treatment 479276.0 -280000.0 -0.59 486809.0 -316000.0 -0.72 -0.9267 -0.9955 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C01 compound treatment 460075.0 -299000.0 -0.63 512086.0 -290000.0 -0.66 -0.9148 -0.9998 1006770 Maybridge3_005325 CCOC(=O)c1cc2ccccc2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C02 compound treatment 583568.0 -175000.0 -0.37 738325.0 -64100.0 -0.15 -0.366 -0.9163 2078085 Maybridge3_005326 CC(C)(C)C(=O)/C=C\1/Nc2ccccc2NC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C03 compound treatment 724334.0 -34700.0 -0.07 929314.0 127000.0 0.29 0.152 0.5106 2078086 Maybridge3_005327 CCOC(=O)Cn1c2ccccc2c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C04 compound treatment 844205.0 85200.0 0.18 1097103.0 295000.0 0.67 0.6015 0.8668 1118001 Maybridge3_005328 CN1C(CC(=O)C2(O)CCCCC12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C05 compound treatment 973000.0 214000.0 0.45 951541.0 149000.0 0.34 0.5605 0.9897 1590446 Maybridge3_005329 Clc1ccc(Oc2ncccc2NS(=O)(=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C06 compound treatment 1013878.0 255000.0 0.54 1087844.0 285000.0 0.65 0.8409 0.9958 2078087 Maybridge3_005330 CC(=O)OC1C(Oc2ccccc2C1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C07 compound treatment 1189949.0 431000.0 0.91 1123033.0 321000.0 0.73 1.1614 0.9937 1640580 Maybridge3_005331 Cc1ccc(cc1)S(=O)(=O)Nc2ncccc2OCc3cc(F)cc(F)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C08 compound treatment 1187349.0 428000.0 0.91 1198451.0 396000.0 0.9 1.2788 1.0 1606796 Maybridge3_005332 COc1ccccc1C2(O)CCN(Cc3ccccc3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C09 compound treatment 1013739.0 255000.0 0.54 1265561.0 463000.0 1.05 1.1264 0.9519 1547687 Maybridge3_005333 CN1CCN(CC1)C(=O)COc2cc(nc3ccccc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C10 compound treatment 944934.0 186000.0 0.39 1257814.0 455000.0 1.04 1.0108 0.9124 1347240 Maybridge3_005334 OC1CCN(CC1)C(=O)Oc2ccc(Oc3ccccc3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C11 compound treatment 1089314.0 330000.0 0.7 1020927.0 219000.0 0.5 0.8464 0.9859 2078088 Maybridge3_005335 CC(=O)n1c(=O)oc2ccc(C)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C12 compound treatment 1040556.0 282000.0 0.6 1372579.0 570000.0 1.3 1.3387 0.938 1302672 Maybridge3_005336 Cc1n[nH]c(N)c1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C13 compound treatment 1009966.0 251000.0 0.53 1421991.0 620000.0 1.41 1.3723 0.9113 1480604 Maybridge3_005337 CCOC(=O)c1cc2c(Cl)cc(Cl)cc2n1C(=O)OC(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C14 compound treatment 952792.0 194000.0 0.41 1228536.0 426000.0 0.97 0.9755 0.927 1057854 Maybridge3_005338 CCC1NC(CS1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C15 compound treatment 1041395.0 282000.0 0.6 960797.0 158000.0 0.36 0.6779 0.9704 2078089 Maybridge3_005339 COC(=O)c1sc2cc(Cl)ccc2c1OC(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C16 compound treatment 1036920.0 278000.0 0.59 1129823.0 327000.0 0.74 0.943 0.9933 1722093 Maybridge3_005340 CCCSc1ccc2[nH]c(NC(=O)C)nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C17 compound treatment 960775.0 202000.0 0.43 1175644.0 373000.0 0.85 0.9025 0.9497 1383819 Maybridge3_005341 CC1(C)CC(=O)c2ccc(OCc3ccc(F)cc3)cc2O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C18 compound treatment 1061980.0 303000.0 0.64 1341578.0 539000.0 1.23 1.321 0.9545 2078090 Maybridge3_005342 COC(=O)N1C2CC(C=C2)C1(C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C19 compound treatment 1073177.0 314000.0 0.67 1226055.0 424000.0 0.96 1.152 0.9838 2078091 Maybridge3_005343 CCOC(=O)C1=C(SC)/C(=N\O)/NC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C20 compound treatment 1122563.0 364000.0 0.77 1286918.0 485000.0 1.1 1.3239 0.9847 1155369 Maybridge3_005344 Cc1ccc(CN2CCC(CC2)NC(=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C21 compound treatment 1192517.0 433000.0 0.92 1258118.0 456000.0 1.04 1.3825 0.9982 2078092 Maybridge3_005345 O=C/1ON(C(=O)\C1=C\c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C22 compound treatment 1129776.0 371000.0 0.79 1149279.0 347000.0 0.79 1.1134 1.0 1586669 Maybridge3_005346 Cc1ccc(CN2CCN(CC2)c3cccc4[nH]ccc34)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C23 mock treatment 1093367.0 334000.0 0.71 1025727.0 223000.0 0.51 0.8602 0.9866 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 C24 mock treatment 481640.0 -277000.0 -0.59 571596.0 -231000.0 -0.52 -0.7869 -0.9984 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D01 compound treatment 387985.0 -371000.0 -0.79 494932.0 -307000.0 -0.7 -1.0505 -0.9983 1138004 Maybridge3_005347 Clc1ccc(c(Cl)c1)S(=O)(=O)N2CCN(CC2)C(=O)C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D02 compound treatment 875100.0 116000.0 0.25 818736.0 16300.0 0.04 0.2003 0.8047 2078093 Maybridge3_005348 CN(C)C(=O)Oc1nc(SCc2c(F)cccc2Cl)nc(C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D03 compound treatment 1085041.0 326000.0 0.69 1040497.0 238000.0 0.54 0.8715 0.9927 1031352 Maybridge3_005349 O=C(CCCC(=O)c1ccccc1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D04 compound treatment 1192399.0 433000.0 0.92 1087788.0 285000.0 0.65 1.1085 0.9855 2078094 Maybridge3_005350 Clc1cc(Cl)cc(NC(=O)C2CC2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D05 compound treatment 1094500.0 335000.0 0.71 1017486.0 215000.0 0.49 0.8487 0.9833 1144979 Maybridge3_005351 CC1(C)c2ccccc2-n3c1cc(O)c(Cc4ccccc4)c3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D06 compound treatment 930299.0 171000.0 0.36 1112749.0 310000.0 0.71 0.7557 0.9523 1302814 Maybridge3_005352 COCc1cc(=O)oc2cc(OC(=O)N(C)C)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D07 compound treatment 1077354.0 318000.0 0.67 1016799.0 214000.0 0.49 0.8219 0.9872 1426387 Maybridge3_005353 Oc1cc2nnnn2nc1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D08 compound treatment 1178163.0 419000.0 0.89 1031971.0 230000.0 0.52 0.9974 0.9678 2078095 Maybridge3_005354 Nc1ncnc(Nc2ccc(F)cc2Br)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D09 compound treatment 171429.0 -588000.0 -1.25 177564.0 -625000.0 -1.42 -1.8853 -0.9979 1137849 Maybridge3_005355 CCN(CC)CCNc1cc(nc2ccccc12)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D10 compound treatment 912064.0 153000.0 0.32 985183.0 183000.0 0.42 0.5233 0.9925 1616809 Maybridge3_005356 COc1ccccc1Nc2ncnc(n2)n3cccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D11 compound treatment 1143460.0 384000.0 0.81 1133869.0 331000.0 0.75 1.1092 0.9992 2078096 Maybridge3_005357 CC/1C(N(C)C(C\C1=N\O)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D12 compound treatment 1203504.0 444000.0 0.94 1332768.0 530000.0 1.21 1.5189 0.9926 2078097 Maybridge3_005358 COCc1cc(OC(=O)N(C)C)nc(n1)c2ccc(C)c(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D13 compound treatment 1289535.0 531000.0 1.12 1199874.0 397000.0 0.9 1.4343 0.9941 2078098 Maybridge3_005359 CN1C(=O)/C(=C\Nc2ccccc2)/C(=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D14 compound treatment 1180111.0 421000.0 0.89 1363913.0 562000.0 1.28 1.5339 0.9847 1614259 Maybridge3_005360 COCc1cc(=O)oc2cc(NS(=O)(=O)c3ccc(C)cc3)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D15 compound treatment 1104209.0 345000.0 0.73 1097032.0 295000.0 0.67 0.9911 0.999 1460864 Maybridge3_005361 Clc1c(Cc2ccccc2)c(=O)oc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D16 compound treatment 1183024.0 424000.0 0.9 1194734.0 392000.0 0.89 1.2663 1.0 1250098 Maybridge3_005362 Cc1n[nH]c2oc(=O)c(Cc3c(F)cccc3Cl)c(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D17 compound treatment 1027648.0 269000.0 0.57 1159277.0 357000.0 0.81 0.9764 0.985 2078099 Maybridge3_005363 CC(=O)NC(=O)c1ocnc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D18 compound treatment 850955.0 91900.0 0.19 1307407.0 505000.0 1.15 0.9497 0.8155 1307545 Maybridge3_005364 Cc1cc(NCC2CC2)n3nc(Nc4cc(Cl)ccc4C)nc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D19 compound treatment 1250677.0 492000.0 1.04 1295833.0 493000.0 1.12 1.5303 0.9993 2078100 Maybridge3_005365 NC(=O)c1c(/N=C/c2cc(Br)ccc2O)sc3CCCCc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D20 compound treatment 1282334.0 523000.0 1.11 1355604.0 553000.0 1.26 1.6738 0.998 2078101 Maybridge3_005366 CCc1cccc(C)c1NC2=NCCC(=O)S2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D21 compound treatment 1151298.0 392000.0 0.83 1201743.0 399000.0 0.91 1.23 0.999 2078102 Maybridge3_005367 CCOC(=O)c1c(C)n[nH]c1/N=C/c2ccncc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D22 compound treatment 1012891.0 254000.0 0.54 1175784.0 373000.0 0.85 0.9808 0.9758 2078103 Maybridge3_005368 COCc1nc(SCC2CC2)nc(O)c1CC(=C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D23 mock treatment 1098515.0 339000.0 0.72 991272.0 189000.0 0.43 0.8126 0.9695 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 D24 mock treatment 436987.0 -322000.0 -0.68 569558.0 -233000.0 -0.53 -0.8571 -0.9921 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E01 compound treatment 477437.0 -282000.0 -0.6 602031.0 -200000.0 -0.46 -0.7442 -0.9911 1121092 Maybridge3_005369 COc1ccccc1N2CCN(CC(C)Nc3ccccn3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E02 compound treatment 1082720.0 324000.0 0.69 1001028.0 199000.0 0.45 0.8046 0.9794 2078104 Maybridge3_005370 O/N=C(\C1CCCCC1)/c2ccccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E03 compound treatment 1174432.0 415000.0 0.88 1170415.0 368000.0 0.84 1.2144 0.9997 1594825 Maybridge3_005371 Clc1ccc(Oc2ncccc2NC(=O)c3ccccc3Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E04 compound treatment 1196900.0 438000.0 0.93 1228830.0 426000.0 0.97 1.3419 0.9998 1285664 Maybridge3_005372 Cc1cccc2C(=O)C(C(=O)Nc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E05 compound treatment 163666.0 -595000.0 -1.26 167710.0 -635000.0 -1.44 -1.9128 -0.9978 2078105 Maybridge3_005373 CS(=O)(=O)NCCNc1cc(nc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E06 compound treatment 1021829.0 263000.0 0.56 1256865.0 454000.0 1.03 1.1246 0.958 873833 Maybridge3_005374 COC(=O)C(C)(N)Cc1ccc(O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E07 compound treatment 1079972.0 321000.0 0.68 1346798.0 544000.0 1.24 1.3563 0.9603 1378223 Maybridge3_005375 CC(C)(C)c1ccc(Oc2ncccc2NC(=O)c3cccs3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E08 compound treatment 931001.0 172000.0 0.36 1205429.0 403000.0 0.92 0.9057 0.9184 1297666 Maybridge3_005376 COC(=O)C1CN(Cc2ccccc2)CCC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E09 compound treatment 1097482.0 338000.0 0.72 1046832.0 244000.0 0.56 0.9003 0.992 1316338 Maybridge3_005377 Cc1ccc(Sc2ncccc2NS(=O)(=O)c3ccc(F)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E10 compound treatment 1047722.0 289000.0 0.61 1163612.0 361000.0 0.82 1.0135 0.9895 1208025 Maybridge3_005378 CCC1(CCCCN(C)C1=O)c2cccc(OC)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E11 compound treatment 1366536.0 608000.0 1.29 1724499.0 922000.0 2.1 2.3931 0.9726 2078106 Maybridge3_005379 CSc1nccc(n1)c2sc(nc2C)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E12 compound treatment 1535514.0 776000.0 1.65 1601669.0 799000.0 1.82 2.4489 0.9988 1160883 Maybridge3_005380 O=S(=O)(C1CCS(=O)(=O)C1)N2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E13 compound treatment 1212779.0 454000.0 0.96 1585822.0 783000.0 1.78 1.9397 0.9582 1732082 Maybridge3_005381 Cc1ccc2cc(NC(=O)Cc3ccccc3)ccc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E14 compound treatment 1214312.0 455000.0 0.97 1411524.0 609000.0 1.38 1.6618 0.9844 2078107 Maybridge3_005382 COC(=O)Cn1nnnc1c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E15 compound treatment 1110966.0 352000.0 0.75 1249272.0 447000.0 1.02 1.246 0.9885 1265272 Maybridge3_005383 CCOC(=O)COc1ccc(Cl)cc1C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E16 compound treatment 1048422.0 289000.0 0.61 1184914.0 383000.0 0.87 1.0488 0.9854 1035162 Maybridge3_005384 O=C(NCC#N)OCc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E17 compound treatment 1183327.0 424000.0 0.9 1123139.0 321000.0 0.73 1.1517 0.9946 1205724 Maybridge3_005385 CC1(C)CC(=O)c2ccc(OCC(=O)Nc3ccc(Br)cc3)cc2O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E18 compound treatment 1174233.0 415000.0 0.88 1233825.0 431000.0 0.98 1.316 0.9985 1369945 Maybridge3_005386 CC(C1CC1)N(C(=O)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E19 compound treatment 1064651.0 306000.0 0.65 1214741.0 412000.0 0.94 1.121 0.9837 1716844 Maybridge3_005387 CC(=O)N1C(=O)CC(Sc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E20 compound treatment 1030445.0 271000.0 0.58 1182197.0 380000.0 0.86 1.0175 0.9805 1250634 Maybridge3_005388 Clc1ccccc1CN2CCC(CC2)NC(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E21 compound treatment 1101202.0 342000.0 0.73 1253278.0 451000.0 1.03 1.2378 0.9857 2078108 Maybridge3_005389 Cc1ccnc(/N=C\2/N(Cc3ccccc23)c4cc(C)ccn4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E22 compound treatment 1119082.0 360000.0 0.76 1261538.0 459000.0 1.04 1.2779 0.9882 2078109 Maybridge3_005390 Clc1ccc(OCCCN2CCN(Cc3ccccc3)CC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E23 mock treatment 1131589.0 373000.0 0.79 1104975.0 303000.0 0.69 1.0449 0.9976 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 E24 mock treatment 484209.0 -275000.0 -0.58 686597.0 -116000.0 -0.26 -0.5981 -0.9356 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F01 compound treatment 518187.0 -241000.0 -0.51 712771.0 -89600.0 -0.2 -0.5051 -0.9188 1481367 Maybridge3_005391 COC(=O)c1c(O)c2ccccc2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F02 compound treatment 1012964.0 254000.0 0.54 1075421.0 273000.0 0.62 0.8196 0.9975 1668909 Maybridge3_005392 Clc1ccc(cc1)C(=O)Cn2nnc(n2)N3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F03 compound treatment 1023299.0 264000.0 0.56 1179176.0 377000.0 0.86 1.0019 0.9788 2078110 Maybridge3_005393 COc1cc(OC)c(nn1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F04 compound treatment 1022772.0 264000.0 0.56 1087653.0 285000.0 0.65 0.854 0.9973 2078111 Maybridge3_005394 CCCc1c(C)nc(SCC(=O)C(C)(C)C)nc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F05 compound treatment 1052118.0 293000.0 0.62 1262669.0 460000.0 1.05 1.1793 0.969 1197747 Maybridge3_005395 CCc1c(O)nc2sc3cc(OC)ccc3n2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F06 compound treatment 1167602.0 409000.0 0.87 1411063.0 609000.0 1.38 1.591 0.9745 2078112 Maybridge3_005396 COCc1nc(SC)nc(O)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F07 compound treatment 1171335.0 412000.0 0.87 1058554.0 256000.0 0.58 1.0299 0.9805 1137263 Maybridge3_005397 Oc1cc(c2ccccc2)n(c3ccccc3)c(=O)c1S(=O)(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F08 compound treatment 1193523.0 435000.0 0.92 1271467.0 469000.0 1.07 1.4054 0.9973 2078113 Maybridge3_005398 CN(C)C(=O)Oc1cc(nc(n1)C2CC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F09 compound treatment 1161150.0 402000.0 0.85 1334653.0 532000.0 1.21 1.4585 0.9853 1556741 Maybridge3_005399 Clc1cc2[nH]cc(c3nnnn3c4ccccc4)c2cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F10 compound treatment 903920.0 145000.0 0.31 1791179.0 989000.0 2.25 1.8068 0.7963 1631105 Maybridge3_005400 CC(C)CCc1c(C)nc(NC(=O)C)nc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F11 compound treatment 1365243.0 606000.0 1.29 1715687.0 913000.0 2.08 2.377 0.9734 2078114 Maybridge3_005401 COc1ccc(cc1)C2C/C(=N/O)/C(C)C(N2)c3ccc(OC)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F12 compound treatment 1295189.0 536000.0 1.14 1771863.0 969000.0 2.2 2.3623 0.9526 2078115 Maybridge3_005402 COCc1nc(SCC(=O)C(C)(C)C)nc(O)c1CC(=C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F13 compound treatment 1515529.0 757000.0 1.6 1524874.0 722000.0 1.64 2.2955 0.9999 1006417 Maybridge3_005403 N#CC(Cc1ccccc1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F14 compound treatment 1242430.0 483000.0 1.02 1183112.0 381000.0 0.87 1.3367 0.9965 2078116 Maybridge3_005404 CC(=C)Cc1c(C)nn(c1O)S(=O)(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F15 compound treatment 1260239.0 501000.0 1.06 1365541.0 563000.0 1.28 1.6567 0.9957 2078117 Maybridge3_005405 COc1ccccc1Oc2cccc(C)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F16 compound treatment 975890.0 217000.0 0.46 1290432.0 488000.0 1.11 1.1097 0.9239 2078118 Maybridge3_005406 Cc1ccc(Cn2nnc(n2)c3cc(Cl)cc(Cl)c3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F17 compound treatment 916536.0 158000.0 0.33 1251255.0 449000.0 1.02 0.9577 0.8919 1666967 Maybridge3_005407 CC(C)C1OCc2cnc(C)c(O)c2CO1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F18 compound treatment 1083284.0 324000.0 0.69 1133344.0 331000.0 0.75 1.0181 0.999 2078119 Maybridge3_005408 Cc1ccc(Cc2nn[nH]n2)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F19 compound treatment 1078764.0 320000.0 0.68 1580953.0 779000.0 1.77 1.7309 0.9132 1222962 Maybridge3_005409 CC(O)C(Nc1ccccc1CC(=O)OC(C)(C)C)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F20 compound treatment 928571.0 170000.0 0.36 1219305.0 417000.0 0.95 0.9244 0.9119 2078120 Maybridge3_005410 CCc1cccc(C)c1N(C(=O)C)C2=NCCC(=O)S2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F21 compound treatment 960899.0 202000.0 0.43 1249530.0 447000.0 1.02 1.0214 0.9261 2078121 Maybridge3_005411 CCN(CC)C(=O)Oc1ccc2c(cc(=O)oc2c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F22 compound treatment 1002360.0 243000.0 0.52 1105431.0 303000.0 0.69 0.8519 0.9898 2078122 Maybridge3_005412 COCc1nc(nc(O)c1CC2CC2)c3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F23 mock treatment 1181869.0 423000.0 0.9 1040930.0 239000.0 0.54 1.0173 0.971 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 F24 mock treatment 931766.0 173000.0 0.37 820500.0 18100.0 0.04 0.2881 0.7817 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G01 compound treatment 1048556.0 290000.0 0.61 786265.0 -16100.0 -0.04 0.4081 0.6637 1921432 Maybridge3_005413 COc1ccccc1NC(=O)/C=C/c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G02 compound treatment 939255.0 180000.0 0.38 1101178.0 299000.0 0.68 0.7505 0.963 2078123 Maybridge3_005414 C/C(=N\O)/c1c(O)cc(c2ccccc2)n(c3ccccc3)c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G03 compound treatment 921296.0 162000.0 0.34 1029135.0 227000.0 0.52 0.6078 0.9807 2078124 Maybridge3_005415 COc1ccc(Oc2ncccc2NC(=O)c3ccco3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G04 compound treatment 1071292.0 312000.0 0.66 1064925.0 263000.0 0.6 0.8902 0.9987 2078125 Maybridge3_005416 OC(=O)CSCCc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G05 compound treatment 1033467.0 274000.0 0.58 999200.0 197000.0 0.45 0.7278 0.9916 1559760 Maybridge3_005417 COc1ccc(cc1)S(=O)(=O)Nc2ncccc2OCc3cc(F)cc(F)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G06 compound treatment 1190862.0 432000.0 0.92 1197996.0 396000.0 0.9 1.2833 1.0 1620309 Maybridge3_005418 CC(C)(C)NC(=O)c1cccc2-c3ccccc3C(=O)c21 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G07 compound treatment 261238.0 -498000.0 -1.06 304205.0 -498000.0 -1.13 -1.5471 -0.9994 1592388 Maybridge3_005419 COc1ccc2nc(cc(O)c2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G08 compound treatment 1043534.0 285000.0 0.6 939867.0 137000.0 0.31 0.6475 0.9531 1478003 Maybridge3_005420 CC1(C)CC(CC(C)(C)N1)Nc2ccc(Nc3ccccc3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G09 compound treatment 1177223.0 418000.0 0.89 1283119.0 481000.0 1.09 1.3997 0.9946 1711358 Maybridge3_005421 CC(C)c1ccc2[nH]c(C)c(CC(=O)O)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G10 compound treatment 1248148.0 489000.0 1.04 1245202.0 443000.0 1.01 1.4451 0.9999 1707121 Maybridge3_005422 NC(=O)c1cn(C2CCCCC2)c3ccccc3c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G11 compound treatment 1321295.0 562000.0 1.19 538846.0 -264000.0 -0.6 0.4192 0.3142 2078126 Maybridge3_005423 Nc1ccc(SCc2ccccc2)c(C#N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G12 compound treatment 1228739.0 470000.0 1.0 1523799.0 721000.0 1.64 1.8639 0.9714 1377868 Maybridge3_005424 O=S(=O)(NCc1ccccc1)C2CCS(=O)(=O)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G13 compound treatment 1508638.0 750000.0 1.59 1281047.0 479000.0 1.09 1.8932 0.9829 1673408 Maybridge3_005425 COc1nc(C)cc(C)c1C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G14 compound treatment 1343995.0 585000.0 1.24 1232916.0 431000.0 0.98 1.569 0.9931 1158878 Maybridge3_005426 OC(=O)CNC(=O)CSc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G15 compound treatment 1388307.0 629000.0 1.33 1152506.0 350000.0 0.8 1.5062 0.9695 2078127 Maybridge3_005427 CC(=O)Nc1ccc(Cl)cc1C(=O)OCC(=O)c2ccc(Br)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G16 compound treatment 1154084.0 395000.0 0.84 1107177.0 305000.0 0.69 1.0822 0.9956 2078128 Maybridge3_005428 CC(C)SCC(=O)Nc1ccc(Br)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G17 compound treatment 1365173.0 606000.0 1.29 994492.0 192000.0 0.44 1.2175 0.897 1686101 Maybridge3_005429 Cc1oc2cc(O)cc(O)c2c(=O)c1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G18 compound treatment 1222419.0 463000.0 0.98 1224935.0 423000.0 0.96 1.3739 0.9999 2078129 Maybridge3_005430 NC(=O)c1ccc(o1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G19 compound treatment 1257387.0 498000.0 1.06 1027339.0 225000.0 0.51 1.1087 0.9445 1139456 Maybridge3_005431 OC(=O)CN1C(=O)CC(Sc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G20 compound treatment 1153687.0 395000.0 0.84 831041.0 28600.0 0.07 0.6377 0.7598 1735473 Maybridge3_005432 COc1ccccc1C2CCN(Cc3ccccc3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G21 compound treatment 997083.0 238000.0 0.5 917728.0 115000.0 0.26 0.5423 0.9535 2078130 Maybridge3_005433 OCC(O)C(O)C(O)C(=O)Nc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G22 compound treatment 979687.0 221000.0 0.47 887291.0 84900.0 0.19 0.4673 0.9233 1254465 Maybridge3_005434 O=C(NC1CCN(Cc2ccccc2)CC1)C3CCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G23 mock treatment 832005.0 73000.0 0.15 830569.0 28200.0 0.06 0.1547 0.9238 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 G24 mock treatment 932697.0 174000.0 0.37 755107.0 -47300.0 -0.11 0.1843 0.4805 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H01 compound treatment 840930.0 81900.0 0.17 799299.0 -3100.0 -0.01 0.1178 0.6779 1295043 Maybridge3_005435 CCc1c(O)c2ccccc2n(C)c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H02 compound treatment 1035220.0 276000.0 0.59 1183643.0 381000.0 0.87 1.0269 0.9818 1351100 Maybridge3_005436 Clc1ccc(cc1Cl)C(=O)Cn2nnc(n2)N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H03 compound treatment 932750.0 174000.0 0.37 1111613.0 309000.0 0.7 0.7575 0.9545 1248478 Maybridge3_005437 Cc1ccc(Nc2ccccc2)nn1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H04 compound treatment 1121635.0 363000.0 0.77 1121390.0 319000.0 0.73 1.0564 0.9996 2078131 Maybridge3_005438 CN(C)C(=O)Oc1cc(C)nc(SCC(=O)C(C)(C)C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H05 compound treatment 1160592.0 402000.0 0.85 1079849.0 277000.0 0.63 1.048 0.9891 1442972 Maybridge3_005439 Cc1c(O)[nH]c2n(ncc2c1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H06 compound treatment 1251366.0 492000.0 1.04 1332947.0 531000.0 1.21 1.591 0.9974 1248545 Maybridge3_005440 CSc1ccccc1Nc2ncnc(N)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H07 compound treatment 1168424.0 409000.0 0.87 1153478.0 351000.0 0.8 1.1781 0.9991 1342353 Maybridge3_005441 CN(C)C(=S)Sc1c(O)c2ccccc2n(C)c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H08 compound treatment 1041045.0 282000.0 0.6 1268822.0 466000.0 1.06 1.1726 0.9632 2078132 Maybridge3_005442 CN(C)C(=O)Oc1cc(nc(n1)C2CC2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H09 compound treatment 1446794.0 688000.0 1.46 1369089.0 567000.0 1.29 1.942 0.9981 2078133 Maybridge3_005443 O=S1(=O)N=S(c2ccccc21)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H10 compound treatment 1542606.0 784000.0 1.66 750939.0 -51500.0 -0.12 1.0919 0.6557 2078134 Maybridge3_005444 Cc1cc(Br)ccc1Nc2ncnc(n2)n3cccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H11 compound treatment 1696147.0 937000.0 1.99 1449270.0 647000.0 1.47 2.4447 0.989 1615119 Maybridge3_005445 CC(C)C1(O)c2ccccc2-c3ncccc31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H12 compound treatment 1766811.0 1010000.0 2.14 1791779.0 989000.0 2.25 3.1013 0.9997 2078135 Maybridge3_005446 CN(C)C(=O)Oc1cc(nc(n1)c2ccc(C)c(Cl)c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H13 compound treatment 1629687.0 871000.0 1.85 1788585.0 986000.0 2.24 2.8906 0.9953 2078136 Maybridge3_005447 N#CC1(CC1)c2ccccc2C3(CC3)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H14 compound treatment 1507889.0 749000.0 1.59 1732307.0 930000.0 2.11 2.6175 0.99 2078137 Maybridge3_005448 COCc1cc(OC(C)C)nc(n1)c2cccc(C)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H15 compound treatment 981893.0 223000.0 0.47 1212230.0 410000.0 0.93 0.993 0.9505 1438947 Maybridge3_005449 C(Cc1ccc(OCc2ccccc2)cc1)C3OCCO3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H16 compound treatment 1368680.0 610000.0 1.29 1505808.0 703000.0 1.6 2.0447 0.9944 2078138 Maybridge3_005450 Clc1cc(Cl)cc(c1)c2nnn(CC(=O)c3ccc4ccccc4c3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H17 compound treatment 1092784.0 334000.0 0.71 1479465.0 677000.0 1.54 1.5888 0.9378 1068086 Maybridge3_005451 O=C(NCCc1c[nH]c2ccccc12)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H18 compound treatment 875877.0 117000.0 0.25 1248192.0 446000.0 1.01 0.8918 0.8548 1458941 Maybridge3_005452 CC(=O)Nc1ccc(cc1)S(=O)(=O)NC2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H19 compound treatment 1461640.0 703000.0 1.49 1358763.0 556000.0 1.26 1.9477 0.9967 2078139 Maybridge3_005453 NC(=O)c1c(/N=C/c2ccccc2Cl)sc3CCCCc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H20 compound treatment 1236764.0 478000.0 1.01 1102342.0 300000.0 0.68 1.1984 0.9815 2078140 Maybridge3_005454 CCc1cccc(C)c1N(C(=O)c2ccco2)C3=NCCC(=O)S3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H21 compound treatment 1205457.0 446000.0 0.95 1098161.0 296000.0 0.67 1.1447 0.986 1338065 Maybridge3_005455 Cc1c(Cc2c(F)cccc2Cl)c(=O)oc3cc(O)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H22 compound treatment 1209297.0 450000.0 0.95 1108552.0 306000.0 0.7 1.1672 0.988 1538410 Maybridge3_005456 CN(C)C(=O)Oc1ccc2c(C)c(Cc3ccc(F)cc3)c(=O)oc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H23 mock treatment 1159931.0 401000.0 0.85 988748.0 186000.0 0.42 0.9006 0.9483 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 H24 mock treatment 527469.0 -232000.0 -0.49 805025.0 2630.0 0.01 -0.3429 -0.6985 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I01 compound treatment 749545.0 -9480.0 -0.02 922809.0 120000.0 0.27 0.1794 0.6535 1144487 Maybridge3_005457 COc1ccc(Oc2ncccc2NC(=O)c3ccc(C)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I02 compound treatment 1195906.0 437000.0 0.93 1305051.0 503000.0 1.14 1.463 0.9946 2078141 Maybridge3_005458 O=C(N1C=Cc2ccccc2C1C#N)C3=CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I03 compound treatment 1253140.0 494000.0 1.05 1280563.0 478000.0 1.09 1.5094 0.9998 1306223 Maybridge3_005459 CC(=O)N1CCC(CC1)c2c[nH]c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I04 compound treatment 1164055.0 405000.0 0.86 1164142.0 362000.0 0.82 1.1887 0.9998 2078142 Maybridge3_005460 OC(Cn1cncn1)c2ccc(Cl)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I05 compound treatment 1581711.0 823000.0 1.74 1288336.0 486000.0 1.1 2.0145 0.9757 1710402 Maybridge3_005461 Fc1cc(F)cc(COc2cccnc2NS(=O)(=O)c3cccc(Cl)c3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I06 compound treatment 1491621.0 733000.0 1.55 1436823.0 634000.0 1.44 2.1181 0.9993 1004100 Maybridge3_005462 CC(=O)Nc1ccc(cc1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I07 compound treatment 1285905.0 527000.0 1.12 1354485.0 552000.0 1.26 1.6774 0.9983 1124590 Maybridge3_005463 Cc1ccc(Sc2ncccc2NC(=O)C3CC3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I08 compound treatment 1183716.0 425000.0 0.9 1295087.0 493000.0 1.12 1.4287 0.9941 2078143 Maybridge3_005464 COC(=O)/C(=C/C(=O)c1ccc(Cl)cc1)/O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I09 compound treatment 1791747.0 1030000.0 2.19 1389240.0 587000.0 1.33 2.4915 0.9718 1557900 Maybridge3_005465 COc1ccc(cc1)C(=O)Nc2cccnc2Sc3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I10 compound treatment 1485785.0 727000.0 1.54 1628683.0 826000.0 1.88 2.4178 0.9952 1558318 Maybridge3_005466 C=CCCN1C(=O)CN=C(c2ccccc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I11 compound treatment 1495263.0 736000.0 1.56 1298220.0 496000.0 1.13 1.9008 0.9872 2078144 Maybridge3_005467 Cc1nc(sc1c2ccnc(N)n2)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I12 compound treatment 978703.0 220000.0 0.47 1405886.0 603000.0 1.37 1.2995 0.8969 2078145 Maybridge3_005468 O=C(/C(=C/1\Nc2ccccc2S1)/C#N)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I13 compound treatment 1617797.0 859000.0 1.82 1320174.0 518000.0 1.18 2.1197 0.9777 1162575 Maybridge3_005469 COc1nc(C)cc(C)c1C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I14 compound treatment 1795027.0 1040000.0 2.2 1460391.0 658000.0 1.5 2.6108 0.9825 1029435 Maybridge3_005470 NC(=O)CNC(=O)c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I15 compound treatment 1354194.0 595000.0 1.26 1357636.0 555000.0 1.26 1.7848 1.0 2078146 Maybridge3_005471 COc1ccccc1/C=C/2\Cc3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I16 compound treatment 1513654.0 755000.0 1.6 1520530.0 718000.0 1.63 2.2857 0.9999 2078147 Maybridge3_005472 CCOC(=O)Cc1csc(NC(=O)C/C=C/C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I17 compound treatment 1669184.0 910000.0 1.93 1312908.0 511000.0 1.16 2.1851 0.9704 2078148 Maybridge3_005473 COc1ccc(cc1)C(=O)Sc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I18 compound treatment 1635848.0 877000.0 1.86 1540044.0 738000.0 1.68 2.5003 0.9987 2078149 Maybridge3_005474 CC(=O)Nc1cccc(Oc2c(F)c(F)c(F)c(F)c2F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I19 compound treatment 1337952.0 579000.0 1.23 1086459.0 284000.0 0.65 1.3245 0.955 1311180 Maybridge3_005475 O=C1CC(c2ccccc2)S(=O)(=O)c3ccccc3N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I20 compound treatment 1240347.0 481000.0 1.02 1224860.0 422000.0 0.96 1.4007 0.9995 1220868 Maybridge3_005476 O=C(NC1CCN(Cc2ccc3ccccc3c2)CC1)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I21 compound treatment 1130639.0 372000.0 0.79 1190667.0 388000.0 0.88 1.1813 0.9984 1045701 Maybridge3_005477 OC1CC(Oc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I22 compound treatment 1065766.0 307000.0 0.65 1094649.0 292000.0 0.66 0.9297 0.9999 1258566 Maybridge3_005478 CC(=O)Nc1ccc(cc1)S(=O)(=O)NC2CCN(Cc3ccccc3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I23 mock treatment 1124151.0 365000.0 0.77 1115123.0 313000.0 0.71 1.0501 0.9991 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 I24 mock treatment 639210.0 -120000.0 -0.25 829922.0 27500.0 0.06 -0.1354 -0.5174 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J01 compound treatment 533626.0 -225000.0 -0.48 675884.0 -127000.0 -0.29 -0.5413 -0.9705 2078150 Maybridge3_005479 CCOc1ccc(cc1)C(=O)/C=C/C(=O)Nc2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J02 compound treatment 1172351.0 413000.0 0.88 1257820.0 455000.0 1.04 1.3518 0.9966 1238462 Maybridge3_005480 Clc1cccc(Cl)c1Cn2nnc(n2)N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J03 compound treatment 952878.0 194000.0 0.41 1266651.0 464000.0 1.06 1.0369 0.9155 1438952 Maybridge3_005481 N(c1ccccc1)c2ccc(nn2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J04 compound treatment 1018650.0 260000.0 0.55 1214378.0 412000.0 0.94 1.0515 0.9679 1291127 Maybridge3_005482 CC(C)(C)C(=O)Cn1nnc(n1)N2CCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J05 compound treatment 1163003.0 404000.0 0.86 1298084.0 496000.0 1.13 1.4025 0.9908 1212941 Maybridge3_005483 CCCCc1c(O)nc2sc3ccccc3n2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J06 compound treatment 1710855.0 952000.0 2.02 1320539.0 518000.0 1.18 2.2598 0.9672 2078151 Maybridge3_005484 COCc1cc(OC(=O)N(C)C)nc(n1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J07 compound treatment 1521612.0 763000.0 1.62 1175428.0 373000.0 0.85 1.7428 0.9547 2078152 Maybridge3_005485 COC(=O)C1=C(C)NC(=C(C1c2ccc(o2)c3ccccc3C(F)(F)F)C(=O)OC)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J08 compound treatment 1394577.0 636000.0 1.35 1278272.0 476000.0 1.08 1.7178 0.9941 2078153 Maybridge3_005486 Cc1cc(O)nc(n1)c2ccc(cc2)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J09 compound treatment 1632198.0 873000.0 1.85 1316571.0 514000.0 1.17 2.1355 0.9754 1202036 Maybridge3_005487 NS(=O)(=O)c1ccccc1Sc2ccccc2C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J10 compound treatment 1643551.0 885000.0 1.88 1294964.0 493000.0 1.12 2.1178 0.9696 1716332 Maybridge3_005488 CC(=C)Cc1c(C)nc(N)nc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J11 compound treatment 1525486.0 766000.0 1.62 1120141.0 318000.0 0.72 1.6598 0.9334 2078154 Maybridge3_005489 CCCC/1C(NC(C\C1=N\O)c2ccco2)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J12 compound treatment 1956236.0 1200000.0 2.54 1097341.0 295000.0 0.67 2.2688 0.8643 2078155 Maybridge3_005490 Cc1ccc(cc1Cl)c2nnn(CC(=O)C(C)(C)C)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J13 compound treatment 1728850.0 970000.0 2.06 1219609.0 417000.0 0.95 2.1245 0.9383 2078156 Maybridge3_005491 COC(=O)C(Cc1ccccc1)(Cc2ccccc2)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J14 compound treatment 1985142.0 1230000.0 2.6 1364137.0 562000.0 1.28 2.7411 0.9465 2078157 Maybridge3_005492 CCCCc1c(O)nc(nc1COC)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J15 compound treatment 1941365.0 1180000.0 2.51 1545700.0 743000.0 1.69 2.9673 0.9816 2078158 Maybridge3_005493 CC(=O)Oc1c(C)c(C)c2oc(=O)ccc2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J16 compound treatment 1579666.0 821000.0 1.74 1581113.0 779000.0 1.77 2.4821 1.0 2078159 Maybridge3_005494 Cn1nnc(n1)c2cc(Cl)cc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J17 compound treatment 1599763.0 841000.0 1.78 1216847.0 414000.0 0.94 1.9266 0.9556 1532186 Maybridge3_005495 O=C1COc2ccccc2N1Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J18 compound treatment 1715568.0 957000.0 2.03 1402802.0 600000.0 1.37 2.3991 0.9814 2078160 Maybridge3_005496 CCCc1cc(O)nc(n1)c2cccc(C)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J19 compound treatment 1313847.0 555000.0 1.18 1154861.0 352000.0 0.8 1.3983 0.9825 2078161 Maybridge3_005497 CN(C)/C=C\c1ccnc(c1)c2cc(/C=C\N(C)C)ccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J20 compound treatment 1155336.0 396000.0 0.84 1179873.0 377000.0 0.86 1.2009 0.9999 2078162 Maybridge3_005498 Fc1cccc(NC2=NCCCC(=O)S2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J21 compound treatment 1405525.0 647000.0 1.37 1425917.0 624000.0 1.42 1.9715 0.9999 2078163 Maybridge3_005499 Oc1cc2oc(=O)cc(c2cc1Cl)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J22 compound treatment 1186070.0 427000.0 0.91 1022862.0 220000.0 0.5 0.9946 0.9611 2078164 Maybridge3_005500 CCCc1nc(SCC(=O)c2ccc(Cl)cc2)nc(OC(=O)N(C)C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J23 mock treatment 1043779.0 285000.0 0.6 1035462.0 233000.0 0.53 0.8015 0.9979 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 J24 mock treatment 545527.0 -213000.0 -0.45 789890.0 -12500.0 -0.03 -0.3401 -0.7501 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K01 compound treatment 733449.0 -25600.0 -0.05 736287.0 -66100.0 -0.15 -0.1446 -0.9051 2078165 Maybridge3_005501 COc1ccc(Oc2ncccc2NC(=O)c3ccccc3C(F)(F)F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K02 compound treatment 944286.0 185000.0 0.39 755519.0 -46900.0 -0.11 0.2024 0.4972 2078166 Maybridge3_005502 CCCc1ccc(nc1)c2ccc(C#N)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K03 compound treatment 150763.0 -608000.0 -1.29 148058.0 -654000.0 -1.49 -1.9637 -0.9975 1198835 Maybridge3_005503 NCCNc1cc(nc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K04 compound treatment 1093158.0 334000.0 0.71 963044.0 161000.0 0.37 0.7591 0.9525 1572113 Maybridge3_005504 Cc1ccc(cc1)C(=O)OCC2OC(CC2OC(=O)c3ccc(C)cc3)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K05 compound treatment 995041.0 236000.0 0.5 1008154.0 206000.0 0.47 0.6846 0.9994 1597421 Maybridge3_005505 Cc1ccc(Sc2ncccc2NC(=O)c3ccc(C)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K06 compound treatment 1164428.0 405000.0 0.86 1254650.0 452000.0 1.03 1.3348 0.996 1723862 Maybridge3_005506 Clc1ccc2n(CN3CCOCC3)c4ccccc4c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K07 compound treatment 1168936.0 410000.0 0.87 1044534.0 242000.0 0.55 1.0037 0.9757 1199418 Maybridge3_005507 Cc1ccc(Sc2ncccc2NC(=O)Cc3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K08 compound treatment 946753.0 188000.0 0.4 1009706.0 207000.0 0.47 0.6147 0.9965 1276282 Maybridge3_005508 CNC(=O)c1ccccc1Sc2ccc(OC)cc2C(=O)NC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K09 compound treatment 1290289.0 531000.0 1.13 1139350.0 337000.0 0.77 1.3381 0.9824 1130288 Maybridge3_005509 NC(=O)c1ccccc1NC(=O)c2ccoc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K10 compound treatment 1069670.0 311000.0 0.66 1186273.0 384000.0 0.87 1.0828 0.9904 1262977 Maybridge3_005510 CCCCC1(O)CCN(Cc2ccccc2)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K11 compound treatment 1476148.0 717000.0 1.52 1140605.0 338000.0 0.77 1.6187 0.9501 2078167 Maybridge3_005511 Cc1cc(N2CCN(CC2)C(=O)/C=C/C(=O)O)c3ccccc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K12 compound treatment 1551973.0 793000.0 1.68 1470596.0 668000.0 1.52 2.2629 0.9987 1732918 Maybridge3_005512 O=S1(=O)CC(CS(=O)(=O)C1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K13 compound treatment 1400408.0 641000.0 1.36 1104078.0 302000.0 0.69 1.4465 0.9498 2078168 Maybridge3_005513 OCCNc1nc2ccccc2nc1NCCO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K14 compound treatment 1367669.0 609000.0 1.29 1150844.0 348000.0 0.79 1.4726 0.9726 1413105 Maybridge3_005514 C(Sc1ccccn1)c2cccc(CSc3ccccn3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K15 compound treatment 1436688.0 678000.0 1.44 1147932.0 346000.0 0.79 1.5713 0.9597 1732657 Maybridge3_005515 NC(=O)c1cccc2cccc(Sc3ccccc3)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K16 compound treatment 1000633.0 242000.0 0.51 1038552.0 236000.0 0.54 0.7418 0.9997 1146462 Maybridge3_005516 CCOC(=O)c1ccc(NC(=O)CSc2nccn2C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K17 compound treatment 1138195.0 379000.0 0.8 1003388.0 201000.0 0.46 0.8915 0.9642 1624690 Maybridge3_005517 OC(COc1ccc(F)cc1)(c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K18 compound treatment 1061157.0 302000.0 0.64 1183826.0 381000.0 0.87 1.0661 0.9889 1312048 Maybridge3_005518 CC(C)(C)NS(=O)(=O)C1CCS(=O)(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K19 compound treatment 1291008.0 532000.0 1.13 1053378.0 251000.0 0.57 1.201 0.9502 1731529 Maybridge3_005519 CN1CC(Oc2ccccc2C1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K20 compound treatment 1189325.0 430000.0 0.91 1027718.0 225000.0 0.51 1.0073 0.9628 1425842 Maybridge3_005520 O=C(NC1CCN(CC1)C(=O)C2CCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K21 compound treatment 1193076.0 434000.0 0.92 1026622.0 224000.0 0.51 1.0111 0.9612 2078169 Maybridge3_005521 O=C1CC(c2ccccc2)S(=O)(=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K22 compound treatment 1076021.0 317000.0 0.67 961811.0 159000.0 0.36 0.7315 0.958 1588419 Maybridge3_005522 Cc1cc(c(C)cc1Cl)S(=O)(=O)NC2CCN(Cc3ccccc3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K23 mock treatment 1020816.0 262000.0 0.55 888485.0 86100.0 0.2 0.5308 0.902 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 K24 mock treatment 421917.0 -337000.0 -0.71 735479.0 -66900.0 -0.15 -0.6129 -0.8388 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L01 compound treatment 251806.0 -507000.0 -1.08 331388.0 -471000.0 -1.07 -1.5175 -1.0 2078170 Maybridge3_005523 Oc1ccc(Br)cc1CNc2cccc(c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L02 compound treatment 1029115.0 270000.0 0.57 1082453.0 280000.0 0.64 0.8551 0.9986 1535928 Maybridge3_005524 Fc1cccc(Cn2nnc(n2)N3CCCCC3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L03 compound treatment 1052632.0 294000.0 0.62 1044706.0 242000.0 0.55 0.8297 0.9981 1300241 Maybridge3_005525 COc1cccc(Nc2ccc(nn2)c3ccccc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L04 compound treatment 1150003.0 391000.0 0.83 1039507.0 237000.0 0.54 0.9673 0.9783 2078171 Maybridge3_005526 CN(C)C(=O)Oc1nc(nc(C)c1CC=C)c2ccc(F)c(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L05 compound treatment 1024385.0 265000.0 0.56 1214776.0 412000.0 0.94 1.0607 0.9701 1136104 Maybridge3_005527 Cn1c(=O)c(Sc2ccccc2)c(O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L06 compound treatment 1045988.0 287000.0 0.61 976113.0 174000.0 0.39 0.7094 0.9781 2078172 Maybridge3_005528 CN(C)C(=O)Sc1nnc(C2CC2)n1c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L07 compound treatment 1118606.0 360000.0 0.76 1431849.0 629000.0 1.43 1.551 0.9565 2078173 Maybridge3_005529 CC1=C(C#N)C(C(=C(C)N1)C#N)c2ccc(o2)c3ccccc3C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L08 compound treatment 1166306.0 407000.0 0.86 1385301.0 583000.0 1.33 1.5476 0.9785 1161217 Maybridge3_005530 COCc1cc(O)nc(NC(=O)C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L09 compound treatment 1061115.0 302000.0 0.64 1348702.0 546000.0 1.24 1.3311 0.9525 2078174 Maybridge3_005531 COC(=O)c1ccccc1S2=NS(=O)(=O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L10 compound treatment 968061.0 209000.0 0.44 1366355.0 564000.0 1.28 1.22 0.8993 2078175 Maybridge3_005532 COCc1nc(SC)nc(O)c1CC(=C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L11 compound treatment 1089268.0 330000.0 0.7 1583360.0 781000.0 1.78 1.7506 0.9172 1430946 Maybridge3_005533 CC1C(O)CC(NC1c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L12 compound treatment 1702156.0 943000.0 2.0 1586211.0 784000.0 1.78 2.6739 0.9984 2078176 Maybridge3_005534 Fc1cccc(Cl)c1Cn2nnc(n2)c3ccccc3C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L13 compound treatment 1412826.0 654000.0 1.39 1347213.0 545000.0 1.24 1.8559 0.9984 2078177 Maybridge3_005535 ClC1(Cl)CC1OC(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L14 compound treatment 1610283.0 851000.0 1.8 1316043.0 514000.0 1.17 2.1018 0.9778 2078178 Maybridge3_005536 CC(C)[n+]1c(C)csc1Nc2ccc(F)c(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L15 compound treatment 1005157.0 246000.0 0.52 1040632.0 238000.0 0.54 0.752 0.9998 2078179 Maybridge3_005537 CC(=O)Oc1cccc2C(=O)C=CC(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L16 compound treatment 1461334.0 702000.0 1.49 1867933.0 1070000.0 2.42 2.7658 0.9727 2078180 Maybridge3_005538 CCn1nnc(n1)c2cc(Cl)cc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L17 compound treatment 1231819.0 473000.0 1.0 1223757.0 421000.0 0.96 1.3861 0.9997 1669414 Maybridge3_005539 Clc1ccc(cc1)C(=O)N2C(=O)COc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L18 compound treatment 1037065.0 278000.0 0.59 1185985.0 384000.0 0.87 1.0335 0.9818 2078181 Maybridge3_005540 CCCc1nc(SC)nc(O)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L19 compound treatment 1164734.0 406000.0 0.86 1329389.0 527000.0 1.2 1.4554 0.9868 1650332 Maybridge3_005541 CCOC(=O)C(C(=O)O)c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L20 compound treatment 1242900.0 484000.0 1.03 1152884.0 350000.0 0.8 1.2888 0.9922 1262370 Maybridge3_005542 C(C1CC1)n2nnc(n2)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L21 compound treatment 1165357.0 406000.0 0.86 1152537.0 350000.0 0.8 1.172 0.9992 2078182 Maybridge3_005543 Cc1nnc(Nc2cccc(F)c2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L22 compound treatment 986470.0 227000.0 0.48 1047320.0 245000.0 0.56 0.7347 0.9974 1387562 Maybridge3_005544 CC(C)(C)C(=O)Cn1nnc(n1)c2ccncc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L23 mock treatment 760609.0 1590.0 0.0 1057745.0 255000.0 0.58 0.4129 0.7112 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 L24 mock treatment 488103.0 -271000.0 -0.57 864539.0 62100.0 0.14 -0.3062 -0.5177 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M01 compound treatment 605067.0 -154000.0 -0.33 633357.0 -169000.0 -0.38 -0.5025 -0.9967 2078183 Maybridge3_005545 COc1ccc(Oc2ncccc2NC(=O)c3ccc(OC(F)(F)F)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M02 compound treatment 1328562.0 570000.0 1.21 980488.0 178000.0 0.4 1.1401 0.8952 2078184 Maybridge3_005546 COC(=O)/C=C\1/OC(=CC1=O)c2ccc(OC)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M03 compound treatment 1473794.0 715000.0 1.52 987673.0 185000.0 0.42 1.3693 0.8707 2078185 Maybridge3_005547 Oc1nc(nc2ccccc12)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M04 compound treatment 1438344.0 679000.0 1.44 1042026.0 240000.0 0.54 1.4036 0.9116 1346725 Maybridge3_005548 CCc1c(O)c2ccccc2[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M05 compound treatment 1336343.0 577000.0 1.22 1037351.0 235000.0 0.53 1.2431 0.9309 1384414 Maybridge3_005549 Cc1ccc(Sc2ncccc2NC(=O)c3ccco3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M06 compound treatment 1378523.0 620000.0 1.31 1002493.0 200000.0 0.45 1.2503 0.8996 1380766 Maybridge3_005550 Fc1ccc(cc1)C2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M07 compound treatment 1435195.0 676000.0 1.43 1039663.0 237000.0 0.54 1.395 0.9108 1157232 Maybridge3_005551 Cn1c(Cn2c3ccccc3c4ccccc24)nnc1SCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M08 compound treatment 1200077.0 441000.0 0.94 831877.0 29500.0 0.07 0.7086 0.7559 1418277 Maybridge3_005552 OCc1ccccc1Sc2ccc(Cl)cc2C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M09 compound treatment 1488381.0 729000.0 1.55 996599.0 194000.0 0.44 1.4055 0.8741 1547625 Maybridge3_005553 Cc1cc(N2CCN(CC2)C(=O)c3ccco3)c4ccccc4n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M10 compound treatment 1089721.0 331000.0 0.7 998518.0 196000.0 0.45 0.811 0.9761 1549124 Maybridge3_005554 COC(=O)c1ccccc1S(=O)(=O)N2CCc3[nH]c4ccc(F)cc4c3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M11 compound treatment 1474198.0 715000.0 1.52 913297.0 111000.0 0.25 1.2504 0.8135 2078186 Maybridge3_005555 CC(C)(C)OC(=O)n1ccc2cc(Br)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M12 compound treatment 1707661.0 949000.0 2.01 1426685.0 624000.0 1.42 2.4257 0.9854 2078187 Maybridge3_005556 CC(=O)Oc1ccc(cc1)C2NC(CS2)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M13 compound treatment 1085762.0 327000.0 0.69 1326858.0 524000.0 1.19 1.3329 0.9666 1269607 Maybridge3_005557 O=C(Nc1nnc(s1)C2CC2)C3CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M14 compound treatment 1481856.0 723000.0 1.53 1085697.0 283000.0 0.64 1.539 0.9259 1331915 Maybridge3_005558 CCSc1ccc(cc1)C(=O)NCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M15 compound treatment 1201354.0 442000.0 0.94 1181192.0 379000.0 0.86 1.272 0.9991 2078188 Maybridge3_005559 COc1cc(/C=C/2\Cc3ccccc3C2=O)ccc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M16 compound treatment 1079463.0 320000.0 0.68 1210508.0 408000.0 0.93 1.1364 0.9883 1145220 Maybridge3_005560 OCCOc1ccc(C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M17 compound treatment 1127071.0 368000.0 0.78 836011.0 33600.0 0.08 0.6058 0.7727 2078189 Maybridge3_005561 CC(C)C(N)C(O)(c1ccccc1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M18 compound treatment 1249357.0 490000.0 1.04 1181916.0 380000.0 0.86 1.3452 0.9957 2078190 Maybridge3_005562 C/C(=N\O)/c1ccc(OC(=O)c2ccc(Br)o2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M19 compound treatment 1122628.0 364000.0 0.77 1227745.0 425000.0 0.97 1.2289 0.9937 1150780 Maybridge3_005563 NC(=O)COc1ccc(cc1)C2=Nc3ccccc3NC(C2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M20 compound treatment 1099674.0 341000.0 0.72 1150060.0 348000.0 0.79 1.0696 0.999 1198975 Maybridge3_005564 O=C(NC1CCN(CC1)C(=O)c2cccs2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M21 compound treatment 1175617.0 417000.0 0.88 1228042.0 426000.0 0.97 1.3088 0.999 1075344 Maybridge3_005565 CCNc1nc(NC(C)C)nc(SC)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M22 compound treatment 1187475.0 428000.0 0.91 1153562.0 351000.0 0.8 1.2068 0.9979 1339230 Maybridge3_005566 O=S(=O)(NC1CCN(Cc2ccccc2)CC1)c3ccc(C#N)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M23 mock treatment 1097874.0 339000.0 0.72 1067135.0 265000.0 0.6 0.9336 0.9961 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 M24 mock treatment 557549.0 -201000.0 -0.43 739019.0 -63400.0 -0.14 -0.4039 -0.896 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N01 compound treatment 534389.0 -225000.0 -0.48 642659.0 -160000.0 -0.36 -0.5935 -0.9911 1377737 Maybridge3_005567 Cc1ccc(SC(CC(=O)c2ccc(C)cc2)C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N02 compound treatment 1047084.0 288000.0 0.61 1532046.0 730000.0 1.66 1.6048 0.9079 1428151 Maybridge3_005568 Clc1ccc(Cn2nnc(n2)N3CCCCC3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N03 compound treatment 1159030.0 400000.0 0.85 1351321.0 549000.0 1.25 1.4821 0.9823 2078191 Maybridge3_005569 CC1(C)CC(=C(Sc2ccccc2)C(=O)C1)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N04 compound treatment 1094165.0 335000.0 0.71 1390669.0 588000.0 1.34 1.4481 0.9562 1510914 Maybridge3_005570 Cc1nc(nc(O)c1CC2CC2)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N05 compound treatment 1226980.0 468000.0 0.99 1268593.0 466000.0 1.06 1.451 0.9995 1166245 Maybridge3_005571 Oc1nc2sc3ccccc3n2c(=O)c1c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N06 compound treatment 1333784.0 575000.0 1.22 1524675.0 722000.0 1.64 2.0228 0.9892 2078192 Maybridge3_005572 CCN(CC)C(=O)Oc1cc(COC)nc(n1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N07 compound treatment 1220413.0 461000.0 0.98 1163982.0 362000.0 0.82 1.2729 0.9963 1207911 Maybridge3_005573 CC1=C(C#N)C(C(=C(C)N1)C#N)c2ccc(O)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N08 compound treatment 1308738.0 550000.0 1.17 1270361.0 468000.0 1.06 1.5764 0.999 2078193 Maybridge3_005574 CCCCc1c(C)nc(nc1O)C2CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N09 compound treatment 1276910.0 518000.0 1.1 1402148.0 600000.0 1.36 1.7405 0.9942 1916985 Maybridge3_005575 C/C(=N/O)/c1ccc(OCCO)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N10 compound treatment 1350948.0 592000.0 1.25 1263551.0 461000.0 1.05 1.6287 0.996 2078194 Maybridge3_005576 CCCCc1c(O)nc(SC)nc1COC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N11 compound treatment 1436508.0 677000.0 1.44 1379611.0 577000.0 1.31 1.9435 0.999 1415843 Maybridge3_005577 CCC1C(O)CC(NC1c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N12 compound treatment 1787496.0 1030000.0 2.18 1542280.0 740000.0 1.68 2.7312 0.9918 1400296 Maybridge3_005578 COCc1cc(=O)oc2cc(NC(=O)c3ccc(cc3)C(C)(C)C)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N13 compound treatment 1229365.0 470000.0 1.0 1269705.0 467000.0 1.06 1.4563 0.9995 2078195 Maybridge3_005579 ClC1(Cl)CC1CS(=O)(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N14 compound treatment 1392645.0 634000.0 1.34 1407108.0 605000.0 1.37 1.922 0.9999 2078196 Maybridge3_005580 CS/C(=N\C(C)(C)C)/NCC1CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N15 compound treatment 1481870.0 723000.0 1.53 1472196.0 670000.0 1.52 2.1604 1.0 2078197 Maybridge3_005581 COc1ccc(Oc2ccccc2OC)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N16 compound treatment 682408.0 -76600.0 -0.16 752848.0 -49600.0 -0.11 -0.1945 -0.984 1650125 Maybridge3_005582 Nc1ncnc(Nc2ccc(Cl)cc2C#N)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N17 compound treatment 1145233.0 386000.0 0.82 1427341.0 625000.0 1.42 1.5836 0.9657 1515750 Maybridge3_005583 CCN1CCC(O)(CC1)C#Cc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N18 compound treatment 1246982.0 488000.0 1.03 1617468.0 815000.0 1.85 2.0418 0.9621 2078198 Maybridge3_005584 CCCc1nc(nc(O)c1C(C)C=C)c2ccccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N19 compound treatment 1505411.0 746000.0 1.58 1633914.0 832000.0 1.89 2.4556 0.9961 1712018 Maybridge3_005585 CC(NCc1ccccc1)c2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N20 compound treatment 1196682.0 438000.0 0.93 1651317.0 849000.0 1.93 2.0208 0.9437 2078199 Maybridge3_005586 Fc1ccc(NC2=NCCC(=O)S2)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N21 compound treatment 1299938.0 541000.0 1.15 1700080.0 898000.0 2.04 2.254 0.9628 1130350 Maybridge3_005587 Cc1nc(nc(O)c1CC=C)N2CCSCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N22 compound treatment 1248377.0 489000.0 1.04 1476052.0 674000.0 1.53 1.8166 0.982 1249270 Maybridge3_005588 COCC(=O)Oc1ccc2c(C)c(Cc3ccc(F)cc3)c(=O)oc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N23 mock treatment 999830.0 241000.0 0.51 1471146.0 669000.0 1.52 1.4361 0.8954 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 N24 mock treatment 918806.0 160000.0 0.34 896011.0 93600.0 0.21 0.39 0.9749 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O01 compound treatment 472449.0 -287000.0 -0.61 544323.0 -258000.0 -0.59 -0.8445 -0.9998 2078200 Maybridge3_005589 O=C/1Nc2ccccc2C(=O)\C1=C\Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O02 compound treatment 1047377.0 288000.0 0.61 1065794.0 263000.0 0.6 0.8557 0.9999 1049683 Maybridge3_005590 N#Cc1ccc(cc1)c2ccc(C#N)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O03 compound treatment 1071469.0 312000.0 0.66 987797.0 185000.0 0.42 0.7664 0.9762 1353347 Maybridge3_005591 CC(C)C(=O)n1c2ccc(F)cc2c3nc4ccccc4nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O04 compound treatment 1162162.0 403000.0 0.85 1188290.0 386000.0 0.88 1.2247 0.9999 2078201 Maybridge3_005592 OC(=O)CCc1cccs1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O05 compound treatment 1186898.0 428000.0 0.91 1138383.0 336000.0 0.76 1.1815 0.9963 1585161 Maybridge3_005593 Cc1ccc(Sc2ncccc2NC(=O)c3cccs3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O06 compound treatment 1414442.0 655000.0 1.39 1184631.0 382000.0 0.87 1.597 0.9745 1722952 Maybridge3_005594 CCC1C2=C(CCCC2=O)NC3=C1C(=O)CCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O07 compound treatment 1103000.0 344000.0 0.73 1200580.0 398000.0 0.91 1.1558 0.9942 1337452 Maybridge3_005595 Clc1ccc(Sc2ncccc2NC(=O)C3CC3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O08 compound treatment 1053765.0 295000.0 0.62 1026960.0 225000.0 0.51 0.8028 0.995 1610969 Maybridge3_005596 CC(=O)OCc1ccccc1Sc2ccc(Cl)cc2C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O09 compound treatment 1083631.0 325000.0 0.69 1095827.0 293000.0 0.67 0.9583 0.9999 1738371 Maybridge3_005597 C(CN1CCCCC1)Nc2cc(nc3ccccc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O10 compound treatment 979738.0 221000.0 0.47 807108.0 4710.0 0.01 0.3384 0.7231 1703424 Maybridge3_005598 CC1(C)C2CCC1(C)C(C2)NC(=O)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O11 compound treatment 1156893.0 398000.0 0.84 1025781.0 223000.0 0.51 0.9555 0.9705 2078202 Maybridge3_005599 FC(F)(F)c1cc(nc(OCC(=O)c2ccccc2)c1C#N)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O12 compound treatment 1173055.0 414000.0 0.88 1182472.0 380000.0 0.86 1.2317 1.0 1514301 Maybridge3_005600 Nc1ccc(SCC(=O)O)c(c1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O13 compound treatment 1141160.0 382000.0 0.81 1061660.0 259000.0 0.59 0.9896 0.9878 1223945 Maybridge3_005601 COC(=O)CCC(=O)c1ccn(c1)S(=O)(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O14 compound treatment 1145186.0 386000.0 0.82 989097.0 187000.0 0.42 0.879 0.9532 1134038 Maybridge3_005602 NC(=O)CNC(=O)c1cccs1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O15 compound treatment 1179743.0 421000.0 0.89 1125068.0 323000.0 0.73 1.1494 0.9953 2078203 Maybridge3_005603 O=C1/C(=C/c2c[nH]c3ccccc23)/COc4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O16 compound treatment 1011976.0 253000.0 0.54 1171399.0 369000.0 0.84 0.9724 0.9766 1708769 Maybridge3_005604 OCCOc1ccc(cc1)C2=NCCO2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O17 compound treatment 1016940.0 258000.0 0.55 1180045.0 378000.0 0.86 0.9937 0.9763 2078204 Maybridge3_005605 NC(=O)c1ccccc1Sc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O18 compound treatment 1189642.0 431000.0 0.91 1055879.0 253000.0 0.58 1.053 0.9754 1561379 Maybridge3_005606 CSc1nnc(CCCc2nnc(SC)o2)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O19 compound treatment 1352726.0 594000.0 1.26 1365734.0 563000.0 1.28 1.7956 1.0 2078205 Maybridge3_005607 O=C(CCC(=O)c1cccs1)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O20 compound treatment 1008558.0 250000.0 0.53 1312678.0 510000.0 1.16 1.1944 0.9367 1380599 Maybridge3_005608 O=C(NC1CCN(CC1)C(=O)c2ccco2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O21 compound treatment 1095607.0 337000.0 0.71 1230605.0 428000.0 0.97 1.193 0.9883 1031949 Maybridge3_005609 OC(=O)CCOc1ccc(Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O22 compound treatment 1087670.0 329000.0 0.7 1139647.0 337000.0 0.77 1.0348 0.9989 1513124 Maybridge3_005610 COc1ccc(CCNC(=O)c2ccco2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O23 mock treatment 910466.0 151000.0 0.32 1127217.0 325000.0 0.74 0.7492 0.9304 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 O24 mock treatment 482018.0 -277000.0 -0.59 561197.0 -241000.0 -0.55 -0.803 -0.9994 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P01 compound treatment 427083.0 -332000.0 -0.7 458673.0 -344000.0 -0.78 -1.0502 -0.9986 2078206 Maybridge3_005611 COc1cc(OC)c(Br)cc1Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P02 compound treatment 154323.0 -605000.0 -1.28 128130.0 -674000.0 -1.53 -1.9904 -0.996 1567530 Maybridge3_005612 Cc1cc(Nc2cc(Cl)cc(Cl)c2)nc(N)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P03 compound treatment 616120.0 -143000.0 -0.3 766905.0 -35500.0 -0.08 -0.2713 -0.8653 1401618 Maybridge3_005613 Cc1cccc(Nc2ccc(nn2)c3ccccc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P04 compound treatment 627897.0 -131000.0 -0.28 871334.0 68900.0 0.16 -0.0857 -0.2687 2078207 Maybridge3_005614 COCc1cc(OC(=O)N(C)C)nc(SC)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P05 compound treatment 800183.0 41200.0 0.09 935348.0 133000.0 0.3 0.2754 0.8755 2078208 Maybridge3_005615 C/C(=N\c1ccccc1)/c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P06 compound treatment 827104.0 68100.0 0.14 874488.0 72100.0 0.16 0.218 0.998 2078209 Maybridge3_005616 CSc1nnc(C2CC2)n1c3cccc(Cl)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P07 compound treatment 793217.0 34200.0 0.07 790172.0 -12200.0 -0.03 0.0316 0.4071 1523901 Maybridge3_005617 COC(=O)C1=C(C)NC(=C(C1c2ccccc2)C(=O)OC)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P08 compound treatment 778962.0 19900.0 0.04 717844.0 -84600.0 -0.19 -0.106 -0.5387 2078210 Maybridge3_005618 COCc1nc(nc(O)c1C)c2ccccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P09 compound treatment 771077.0 12100.0 0.03 788767.0 -13600.0 -0.03 -0.0038 -0.0956 1681351 Maybridge3_005619 CC(C)c1cc(O)c(c2ccccc2)c(=O)n1c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P10 compound treatment 769131.0 10100.0 0.02 725295.0 -77100.0 -0.18 -0.1088 -0.6161 1050551 Maybridge3_005620 CCSc1nc(N)cc(O)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P11 compound treatment 649149.0 -110000.0 -0.23 744621.0 -57800.0 -0.13 -0.2576 -0.9633 1446663 Maybridge3_005621 CC1C(NC(C(C)C1=O)c2ccco2)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P12 compound treatment 582985.0 -176000.0 -0.37 649002.0 -153000.0 -0.35 -0.5105 -0.9994 1561669 Maybridge3_005622 COCc1cc(=O)oc2cc(NC(=O)C3CC3)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P13 compound treatment 566300.0 -193000.0 -0.41 620376.0 -182000.0 -0.41 -0.5815 -1.0 2078211 Maybridge3_005623 N#CCOc1ccc2ccccc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P14 compound treatment 639916.0 -119000.0 -0.25 721004.0 -81400.0 -0.19 -0.3094 -0.9883 2078212 Maybridge3_005624 CCC(=O)N(C1=NCCC(=O)S1)c2ccc(cc2)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P15 compound treatment 741964.0 -17100.0 -0.04 766951.0 -35400.0 -0.08 -0.0826 -0.9346 2078213 Maybridge3_005625 Brc1ccc(OCC#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P16 compound treatment 705370.0 -53700.0 -0.11 786822.0 -15600.0 -0.04 -0.1055 -0.8853 2078214 Maybridge3_005626 CCc1cc(O)nc(n1)c2ccc(F)c(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P17 compound treatment 584739.0 -174000.0 -0.37 786176.0 -16200.0 -0.04 -0.2873 -0.7738 2078215 Maybridge3_005627 COC(=O)CCC1CCC(CCC(=O)OC)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P18 compound treatment 557721.0 -201000.0 -0.43 604261.0 -198000.0 -0.45 -0.6203 -0.9996 2078216 Maybridge3_005628 CCCc1nc(nc(O)c1CC=C)c2ccccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P19 compound treatment 654663.0 -104000.0 -0.22 812326.0 9930.0 0.02 -0.1405 -0.6317 1131627 Maybridge3_005629 CC(CO)NC(=O)OCC1c2ccccc2-c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P20 compound treatment 616950.0 -142000.0 -0.3 743758.0 -58600.0 -0.13 -0.3072 -0.9328 2078217 Maybridge3_005630 Fc1ccc(cc1Cl)N(C(=O)c2ccco2)C3=NCCC(=O)S3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P21 compound treatment 519987.0 -239000.0 -0.51 672858.0 -130000.0 -0.29 -0.5666 -0.9667 2078218 Maybridge3_005631 CN(C)C(=S)Oc1ccc2c(cc(=O)oc2c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P22 compound treatment 710415.0 -48600.0 -0.1 863484.0 61100.0 0.14 0.0253 0.1465 1276434 Maybridge3_005632 COCc1cc(=O)oc2cc(OC(=O)C)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P23 mock treatment 484642.0 -274000.0 -0.58 529514.0 -273000.0 -0.62 -0.85 -0.9995 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1446 P24 mock treatment 390274.0 -369000.0 -0.78 485656.0 -317000.0 -0.72 -1.062 -0.9992 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A01 compound treatment 456650.0 -293000.0 -0.62 498989.0 -163000.0 -0.37 -0.7 -0.9694 1345321 Maybridge3_005633 COCc1cc(=O)oc2cc(OC(=O)C)c(Cl)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A02 compound treatment 398379.0 -351000.0 -0.74 431709.0 -230000.0 -0.52 -0.8956 -0.9851 2078219 Maybridge3_005634 CCOC(=O)c1c(/N=C/c2ccccc2O)sc3CCCc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A03 compound treatment 443245.0 -306000.0 -0.65 445757.0 -216000.0 -0.49 -0.8057 -0.9905 2078220 Maybridge3_005635 CC1CC(CC(C)(C)C1)NC(=O)/C=C/C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A04 compound treatment 499212.0 -250000.0 -0.53 621912.0 -39600.0 -0.09 -0.4386 -0.8156 2078221 Maybridge3_005636 O=C(CC1OC(=O)c2ccccc12)c3ccc4ccccc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A05 compound treatment 542737.0 -207000.0 -0.44 479707.0 -182000.0 -0.41 -0.602 -0.9996 1071883 Maybridge3_005637 COc1ccc(CCN2C(=O)CSC2=S)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A06 compound treatment 560123.0 -189000.0 -0.4 433692.0 -228000.0 -0.52 -0.6499 -0.992 2078222 Maybridge3_005638 CSc1cccc(c1)N2C(=O)CSC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A07 compound treatment 444580.0 -305000.0 -0.65 516258.0 -145000.0 -0.33 -0.6904 -0.9515 2078223 Maybridge3_005639 COc1ccc(CC/N=C\2/NCCS2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A08 compound treatment 526707.0 -223000.0 -0.47 491808.0 -170000.0 -0.39 -0.6066 -0.995 2078224 Maybridge3_005640 Clc1ccccc1C2OC(=O)c3ccccc3S2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A09 compound treatment 532065.0 -217000.0 -0.46 600927.0 -60600.0 -0.14 -0.4231 -0.8802 1473832 Maybridge3_005641 COc1cccc(c1)N2C(=O)CC(Sc3ccccc3N)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A10 compound treatment 614735.0 -135000.0 -0.29 580057.0 -81500.0 -0.19 -0.3327 -0.9782 2078225 Maybridge3_005642 Fc1ccc(CSc2nnc(s2)c3ccncc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A11 compound treatment 489288.0 -260000.0 -0.55 596956.0 -64600.0 -0.15 -0.4936 -0.8653 2078226 Maybridge3_005643 COc1cc(OC)cc(c1)/C(=N/O)/N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A12 compound treatment 471601.0 -278000.0 -0.59 601990.0 -59600.0 -0.14 -0.512 -0.8476 2078227 Maybridge3_005644 CC(C)(C)c1ccc(cc1)n2nnnc2c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A13 compound treatment 597973.0 -151000.0 -0.32 647449.0 -14100.0 -0.03 -0.2495 -0.7739 2078228 Maybridge3_005645 C/C(=N\Cc1cccnc1)/c2ccccc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A14 compound treatment 720201.0 -29100.0 -0.06 657566.0 -3980.0 -0.01 -0.05 -0.8023 2078229 Maybridge3_005646 Oc1ccc(Cl)cc1/C=N/Cc2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A15 compound treatment 760540.0 11200.0 0.02 699680.0 38100.0 0.09 0.0781 0.8691 2078230 Maybridge3_005647 CSc1cccc(NC(=O)CC2S/C(=N/c3cccc(SC)c3)/NC2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A16 compound treatment 594872.0 -154000.0 -0.33 609103.0 -52400.0 -0.12 -0.3158 -0.9064 2078231 Maybridge3_005648 NC(=O)C1=C(NC(C(=N1)c2ccccc2)c3ccccc3)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A17 compound treatment 594611.0 -155000.0 -0.33 623971.0 -37600.0 -0.09 -0.2923 -0.8625 2078232 Maybridge3_005649 Oc1ccc(Br)cc1/C=N/Cc2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A18 compound treatment 601262.0 -148000.0 -0.31 491594.0 -170000.0 -0.39 -0.4952 -0.9947 1214261 Maybridge3_005650 Clc1ccc(NC(=O)Oc2ccccc2N3CCSCC3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A19 compound treatment 650677.0 -98600.0 -0.21 597904.0 -63600.0 -0.14 -0.2502 -0.9838 2078233 Maybridge3_005651 Clc1cc(Cl)cc(Nc2n[nH]c(=S)s2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A20 compound treatment 594444.0 -155000.0 -0.33 519317.0 -142000.0 -0.32 -0.4608 -1.0 2078234 Maybridge3_005652 Clc1ccc(Oc2ccccc2N3C(=O)C=CC3=O)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A21 compound treatment 574760.0 -175000.0 -0.37 549985.0 -112000.0 -0.25 -0.441 -0.983 1921450 Maybridge3_005653 OCCSc1nc2ccccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A22 compound treatment 505295.0 -244000.0 -0.52 394573.0 -267000.0 -0.61 -0.795 -0.9968 2078235 Maybridge3_005654 O=C(CC(CC(=O)c1ccccc1)c2ccccc2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A23 mock treatment 474708.0 -275000.0 -0.58 459373.0 -202000.0 -0.46 -0.7367 -0.9932 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 A24 mock treatment 502110.0 -247000.0 -0.52 398217.0 -263000.0 -0.6 -0.7939 -0.9978 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B01 compound treatment 437224.0 -312000.0 -0.66 349443.0 -312000.0 -0.71 -0.9696 -0.9994 1616152 Maybridge3_005655 Brc1ccccc1C2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B02 compound treatment 587945.0 -161000.0 -0.34 713267.0 51700.0 0.12 -0.1588 -0.4389 1211437 Maybridge3_005656 O=C1COCC(=O)N1Cc2csc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B03 compound treatment 763440.0 14100.0 0.03 823520.0 162000.0 0.37 0.2816 0.7621 2078236 Maybridge3_005657 Oc1c(Br)cc(Br)cc1C(=O)NCC2CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B04 compound treatment 941511.0 192000.0 0.41 872159.0 211000.0 0.48 0.6267 0.9968 1229010 Maybridge3_005658 Cc1ccc(nc1)n2cc3ccccc3c2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B05 compound treatment 881305.0 132000.0 0.28 914267.0 253000.0 0.57 0.6041 0.9453 2078237 Maybridge3_005659 CC(=O)SC1CC(=O)N(C1=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B06 compound treatment 955000.0 206000.0 0.44 930301.0 269000.0 0.61 0.7404 0.9863 1500011 Maybridge3_005660 O=C1C(=C(NCCC2=CCCCC2)C#N)C(=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B07 compound treatment 832374.0 83100.0 0.18 848470.0 187000.0 0.42 0.425 0.9239 1131936 Maybridge3_005661 OC(=O)CSCC(=O)Nc1ccc2OCOc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B08 compound treatment 674706.0 -74600.0 -0.16 877453.0 216000.0 0.49 0.2353 0.4562 2078238 Maybridge3_005662 N#CCC1(CCc2ccccc21)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B09 compound treatment 952759.0 203000.0 0.43 823655.0 162000.0 0.37 0.5656 0.9969 2078239 Maybridge3_005663 CSc1nnc(Nc2ccc(Cl)cc2Cl)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B10 compound treatment 793580.0 44300.0 0.09 951680.0 290000.0 0.66 0.5328 0.7997 1071586 Maybridge3_005664 COc1ccc(NC2=CC(=O)N(C2=O)c3ccc(OC)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B11 compound treatment 846860.0 97600.0 0.21 935156.0 274000.0 0.62 0.5861 0.8941 1605725 Maybridge3_005665 CC1SC(N(C1=O)c2ccc(Cl)cc2)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B12 compound treatment 858328.0 109000.0 0.23 992721.0 331000.0 0.75 0.6958 0.8835 2078240 Maybridge3_005666 CC(C)(C)c1ccccc1N2C(=O)C=CC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B13 compound treatment 927265.0 178000.0 0.38 928586.0 267000.0 0.61 0.6961 0.9738 1339068 Maybridge3_005667 Cc1ccc(c(O)c1C)C2(O)C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B14 compound treatment 1099594.0 350000.0 0.74 1022910.0 361000.0 0.82 1.106 0.9987 1172604 Maybridge3_005668 O=C1COCC(=O)N1c2ccccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B15 compound treatment 1093620.0 344000.0 0.73 985807.0 324000.0 0.74 1.0374 1.0 2078241 Maybridge3_005669 Fc1ccc(/C=C/2\SC(=O)N(C2=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B16 compound treatment 997409.0 248000.0 0.53 1040901.0 379000.0 0.86 0.9818 0.9719 2078242 Maybridge3_005670 CCOC(=O)C(N)CSC1CC(=O)N(C1=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B17 compound treatment 1061778.0 312000.0 0.66 938228.0 277000.0 0.63 0.9132 0.9997 2078243 Maybridge3_005671 COc1ccc(Cl)cc1NC(=C2C(=O)c3ccccc3C2=O)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B18 compound treatment 1142939.0 394000.0 0.83 900200.0 239000.0 0.54 0.9737 0.9783 2078244 Maybridge3_005672 CC(C)(C)c1ccc(cc1)c2nnc(N)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B19 compound treatment 1106074.0 357000.0 0.76 1058496.0 397000.0 0.9 1.1729 0.9961 2078245 Maybridge3_005673 COc1ccc(/C=N/CCc2cccs2)c(O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B20 compound treatment 1092554.0 343000.0 0.73 1061341.0 400000.0 0.91 1.1573 0.9939 1677349 Maybridge3_005674 Cc1ccc(CNc2n[nH]c(=S)s2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B21 compound treatment 1128379.0 379000.0 0.8 1034681.0 373000.0 0.85 1.1681 0.9996 1690607 Maybridge3_005675 OC(=O)CCSC1CC(=O)N(C1=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B22 compound treatment 845073.0 95800.0 0.2 861302.0 200000.0 0.45 0.4647 0.9341 2078246 Maybridge3_005676 Cc1ccc(/C=C/2\N3CCC(CC3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B23 mock treatment 710614.0 -38700.0 -0.08 589336.0 -72200.0 -0.16 -0.1741 -0.9486 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 B24 mock treatment 544751.0 -205000.0 -0.43 338559.0 -323000.0 -0.73 -0.8259 -0.9684 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C01 compound treatment 398541.0 -351000.0 -0.74 437006.0 -225000.0 -0.51 -0.8868 -0.9832 2078247 Maybridge3_005677 Fc1ccc(Cn2nnc(n2)c3cccc(c3)C(F)(F)F)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C02 compound treatment 634978.0 -114000.0 -0.24 642164.0 -19400.0 -0.04 -0.2026 -0.8222 2078248 Maybridge3_005678 Oc1ccccc1/C=N/c2sc3CCCc3c2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C03 compound treatment 481129.0 -268000.0 -0.57 532315.0 -129000.0 -0.29 -0.6098 -0.9528 2078249 Maybridge3_005679 Cc1ccc(CNc2ccccn2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C04 compound treatment 734312.0 -15000.0 -0.03 867961.0 206000.0 0.47 0.3094 0.6577 2078250 Maybridge3_005680 CC(/N=C/c1cc(Cl)ccc1O)c2ccc3OCCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C05 compound treatment 723326.0 -26000.0 -0.06 824357.0 163000.0 0.37 0.2228 0.5953 1741192 Maybridge3_005681 Nc1ccccc1SC2CC(=O)N(C2=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C06 compound treatment 894985.0 146000.0 0.31 932995.0 271000.0 0.62 0.6548 0.9488 2078251 Maybridge3_005682 CCn1c2ccccc2c3cc(NC(=O)/C=C/C(=O)O)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C07 compound treatment 943314.0 194000.0 0.41 912323.0 251000.0 0.57 0.694 0.9872 1021361 Maybridge3_005683 OC(=O)CC(NC(=O)c1ccccc1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C08 compound treatment 935397.0 186000.0 0.39 995067.0 334000.0 0.76 0.8151 0.9536 1124743 Maybridge3_005684 CC(C)(C)c1ccc(cc1)c2nc3ccccc3c(=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C09 compound treatment 865361.0 116000.0 0.25 968218.0 307000.0 0.7 0.667 0.9021 1090054 Maybridge3_005685 COc1ccccc1Nc2n[nH]c(=S)s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C10 compound treatment 786137.0 36800.0 0.08 862069.0 201000.0 0.46 0.3776 0.8163 1442578 Maybridge3_005686 Clc1ccc(CN2C(SCC2=O)c3cccnc3)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C11 compound treatment 945340.0 196000.0 0.42 931016.0 269000.0 0.61 0.7271 0.9821 2078252 Maybridge3_005687 Cc1cc(NC(=O)/C=C/C(=O)O)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C12 compound treatment 1089910.0 341000.0 0.72 991887.0 330000.0 0.75 1.0416 0.9998 2078253 Maybridge3_005688 O=C1C(=C(Nc2ccc3OCCOc3c2)C#N)C(=O)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C13 compound treatment 927961.0 179000.0 0.38 889770.0 228000.0 0.52 0.6347 0.988 2078254 Maybridge3_005689 CCc1ccc(Nc2n[nH]c(=S)s2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C14 compound treatment 919934.0 171000.0 0.36 919755.0 258000.0 0.59 0.6709 0.9729 2078255 Maybridge3_005690 OC(=O)/C=C/C(=O)Nc1nccs1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C15 compound treatment 933309.0 184000.0 0.39 919468.0 258000.0 0.59 0.6905 0.9804 2078256 Maybridge3_005691 CSc1cccc(NC(=O)CC2S/C(=N/c3ccc(F)c(F)c3)/NC2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C16 compound treatment 1007692.0 258000.0 0.55 924826.0 263000.0 0.6 0.8106 0.999 2078257 Maybridge3_005692 Clc1cccc(c1)N2CSC(=C(C#N)C#N)SC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C17 compound treatment 778076.0 28800.0 0.06 789535.0 128000.0 0.29 0.2489 0.8371 1915666 Maybridge3_005693 Oc1ccc2ccccc2c1/C=N/Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C18 compound treatment 1075733.0 326000.0 0.69 1002555.0 341000.0 0.78 1.0375 0.9984 2078258 Maybridge3_005694 OC(=O)/C=C/C(=O)Nc1ccc(cc1)C2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C19 compound treatment 1055401.0 306000.0 0.65 1083013.0 421000.0 0.96 1.1364 0.982 2078259 Maybridge3_005695 Oc1ccccc1/C=N/c2ccc(cc2)S(=O)(=O)\N=C\c3ccccc3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C20 compound treatment 1026247.0 277000.0 0.59 1121224.0 460000.0 1.05 1.1541 0.9628 2078260 Maybridge3_005696 Clc1cccc(c1)N2C(=O)C=C(C2=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C21 compound treatment 939743.0 190000.0 0.4 868971.0 207000.0 0.47 0.6189 0.997 2078261 Maybridge3_005697 CCO/C=C\1/SC(=S)N(C1=O)c2cc(OC)cc(c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C22 compound treatment 929505.0 180000.0 0.38 907807.0 246000.0 0.56 0.666 0.9826 1677967 Maybridge3_005698 COc1ccc(Cc2nnc(Nc3ccc(C)cc3)o2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C23 mock treatment 862648.0 113000.0 0.24 803874.0 142000.0 0.32 0.3987 0.9893 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 C24 mock treatment 594733.0 -155000.0 -0.33 469066.0 -192000.0 -0.44 -0.5412 -0.9898 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D01 compound treatment 370744.0 -379000.0 -0.8 445220.0 -216000.0 -0.49 -0.9153 -0.9724 2078262 Maybridge3_005699 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3cc(Cl)cc(Cl)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D02 compound treatment 612033.0 -137000.0 -0.29 694739.0 33200.0 0.08 -0.1524 -0.507 1381937 Maybridge3_005700 OC(=O)c1ccccc1C(=O)NCc2csc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D03 compound treatment 624238.0 -125000.0 -0.27 590257.0 -71300.0 -0.16 -0.3021 -0.9721 1183202 Maybridge3_005701 O=C1CS(=O)(=O)C(N1c2ccccc2)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D04 compound treatment 776442.0 27100.0 0.06 638612.0 -22900.0 -0.05 0.0038 0.0489 2078263 Maybridge3_005702 CCOC(=S)Nc1ccc(OC(F)(F)F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D05 compound treatment 752446.0 3140.0 0.01 729863.0 68300.0 0.16 0.1145 0.7367 1701711 Maybridge3_005703 OC(=O)CCCC(=O)Nc1ccc(F)cc1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D06 compound treatment 808561.0 59300.0 0.13 940070.0 279000.0 0.63 0.5366 0.8312 1461971 Maybridge3_005704 O=c1cc(NCCC2=CCCCC2)c3ccccc3o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D07 compound treatment 762275.0 13000.0 0.03 875178.0 214000.0 0.49 0.3629 0.7459 1127442 Maybridge3_005705 O=C1CSCC(=O)N1c2ccc3OCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D08 compound treatment 901321.0 152000.0 0.32 810533.0 149000.0 0.34 0.4674 0.9997 1217015 Maybridge3_005706 COc1ccc2c(CCCC2(CC#N)C#N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D09 compound treatment 945684.0 196000.0 0.42 911588.0 250000.0 0.57 0.6963 0.9883 1117856 Maybridge3_005707 CSc1nnc(NCc2cccc(Cl)c2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D10 compound treatment 985142.0 236000.0 0.5 850541.0 189000.0 0.43 0.6573 0.9972 1155297 Maybridge3_005708 Clc1cc(Cl)cc(c1)N2C(=O)CC(C2=O)S(=O)(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D11 compound treatment 983140.0 234000.0 0.5 890552.0 229000.0 0.52 0.7187 0.9997 1408183 Maybridge3_005709 CC1SC(N(C1=O)c2ccc(F)cc2F)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D12 compound treatment 1117337.0 368000.0 0.78 1223858.0 562000.0 1.28 1.4557 0.9719 2078264 Maybridge3_005710 OC(=O)/C=C/C(=O)NCc1ccc(F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D13 compound treatment 514556.0 -235000.0 -0.5 472646.0 -189000.0 -0.43 -0.6556 -0.9973 1486931 Maybridge3_005711 COc1ccc(O)c(c1)C(=O)C2N(C(=O)c3ccccc23)c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D14 compound treatment 986285.0 237000.0 0.5 1060866.0 399000.0 0.91 0.9972 0.9611 1657982 Maybridge3_005712 O=C1CCC(=O)N1c2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D15 compound treatment 1040890.0 292000.0 0.62 897418.0 236000.0 0.54 0.8163 0.9975 2078265 Maybridge3_005713 Fc1cccc(F)c1c2nc3ccc(SC#N)cc3c(=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D16 compound treatment 1118176.0 369000.0 0.78 1030607.0 369000.0 0.84 1.1463 0.9994 1723958 Maybridge3_005714 CCOC(=O)C1CSC(CC(=O)Nc2ccccc2)C(=O)N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D17 compound treatment 1113720.0 364000.0 0.77 1031037.0 369000.0 0.84 1.1403 0.9991 1700520 Maybridge3_005715 COc1ccc(Cl)cc1NC(=O)CSCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D18 compound treatment 1134272.0 385000.0 0.82 967825.0 306000.0 0.7 1.0695 0.9969 2078266 Maybridge3_005716 CC(O)c1nc2cc(Cl)ccc2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D19 compound treatment 1091615.0 342000.0 0.73 874977.0 213000.0 0.49 0.8562 0.9809 2078267 Maybridge3_005717 FC(F)(F)c1ccc(NC(C#N)c2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D20 compound treatment 1051773.0 302000.0 0.64 971349.0 310000.0 0.7 0.9514 0.9989 1161511 Maybridge3_005718 COc1ccc(CNc2n[nH]c(=S)s2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D21 compound treatment 1039020.0 290000.0 0.61 812049.0 150000.0 0.34 0.6762 0.9619 2078268 Maybridge3_005719 OC(=O)/C=C/C(=O)Nc1ccc(OC(F)(F)F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D22 compound treatment 908480.0 159000.0 0.34 827641.0 166000.0 0.38 0.5056 0.9984 2078269 Maybridge3_005720 Cc1ccc(cc1F)N2C(=O)CC(CC=C)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D23 mock treatment 955726.0 206000.0 0.44 731799.0 70200.0 0.16 0.4224 0.9067 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 D24 mock treatment 618977.0 -130000.0 -0.28 479017.0 -183000.0 -0.41 -0.4888 -0.9805 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E01 compound treatment 624808.0 -125000.0 -0.26 524610.0 -137000.0 -0.31 -0.4068 -0.9966 2078270 Maybridge3_005721 Cc1cccc(Cl)c1c2nn[nH]n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E02 compound treatment 758764.0 9450.0 0.02 738859.0 77300.0 0.18 0.1385 0.7827 2078271 Maybridge3_005722 OC(=O)/C=C/C(=O)Nc1ccc2OCCOc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E03 compound treatment 903633.0 154000.0 0.33 884362.0 223000.0 0.51 0.5895 0.9776 2078272 Maybridge3_005723 Cc1ccc(CNc2cccnc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E04 compound treatment 916332.0 167000.0 0.35 915021.0 253000.0 0.58 0.6579 0.9726 2078273 Maybridge3_005724 C=CC/N=C/1\NC(=O)C(CC(=O)Nc2ccccc2)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E05 compound treatment 1063466.0 314000.0 0.67 894298.0 233000.0 0.53 0.8451 0.9935 2078274 Maybridge3_005725 CCO/C=C/1\SC(=S)N(CCc2ccc(OC)c(OC)c2)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E06 compound treatment 1220322.0 471000.0 1.0 954500.0 293000.0 0.67 1.177 0.9806 2078275 Maybridge3_005726 CCn1c2ccccc2c3cc(ccc13)N4C(=O)C=CC4=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E07 compound treatment 325780.0 -424000.0 -0.9 313913.0 -348000.0 -0.79 -1.1938 -0.998 2078276 Maybridge3_005727 Cc1c(C)c(C)c(CSC(=N)N)c(C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E08 compound treatment 1122007.0 373000.0 0.79 1007759.0 346000.0 0.79 1.1153 1.0 1660547 Maybridge3_005728 CC(C)(C)c1ccc(cc1)C(=C(C#N)C#N)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E09 compound treatment 934481.0 185000.0 0.39 849050.0 187000.0 0.43 0.579 0.9992 2078277 Maybridge3_005729 O=C1CSC(=S)N1CCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E10 compound treatment 1505591.0 756000.0 1.6 1076244.0 415000.0 0.94 1.8004 0.968 2078278 Maybridge3_005730 Clc1ccc(CSc2nnc(s2)c3ccncc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E11 compound treatment 1274719.0 525000.0 1.11 1146282.0 485000.0 1.1 1.5669 1.0 2078279 Maybridge3_005731 Clc1ccc(Oc2ccc(cc2)N3C(=O)CSC3=S)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E12 compound treatment 1239511.0 490000.0 1.04 929766.0 268000.0 0.61 1.166 0.9677 1184213 Maybridge3_005732 OC(=O)CC(NC(=O)Cc1cccc2ccccc12)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E13 compound treatment 1160041.0 411000.0 0.87 1101746.0 440000.0 1.0 1.3234 0.9976 2078280 Maybridge3_005733 CSc1ccc(cc1)N2C(=O)C=CC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E14 compound treatment 1405304.0 656000.0 1.39 1115990.0 454000.0 1.03 1.7139 0.9893 1701575 Maybridge3_005734 CC(C)CCSc1nnc(N)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E15 compound treatment 1151128.0 402000.0 0.85 1261108.0 600000.0 1.36 1.5662 0.9744 2078281 Maybridge3_005735 Clc1ccc(Cl)c(Nc2nn(c3ccccc3)c(=S)s2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E16 compound treatment 1277953.0 529000.0 1.12 969398.0 308000.0 0.7 1.2874 0.9743 1467444 Maybridge3_005736 OC(=O)CC(CC(=O)Oc1ccc(F)cc1)c2ccc(Cl)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E17 compound treatment 1153591.0 404000.0 0.86 957565.0 296000.0 0.67 1.0819 0.9928 2078282 Maybridge3_005737 Oc1ccc(Br)cc1/C=N/Cc2ccncc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E18 compound treatment 1251496.0 502000.0 1.06 1088798.0 427000.0 0.97 1.4397 0.999 2078283 Maybridge3_005738 O=C1C=CC(=O)N1c2ccc(cc2)C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E19 compound treatment 1260301.0 511000.0 1.08 1092785.0 431000.0 0.98 1.4593 0.9988 2078284 Maybridge3_005739 Cc1ccc(C)c(Nc2n[nH]c(=S)s2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E20 compound treatment 1143150.0 394000.0 0.83 1050427.0 389000.0 0.88 1.2156 0.9996 2078285 Maybridge3_005740 Cc1ccsc1/C=C\2/N=C(OC2=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E21 compound treatment 1212685.0 463000.0 0.98 980135.0 319000.0 0.72 1.2068 0.9888 2078286 Maybridge3_005741 Cc1onc(c1c2n[nH]c(N)c2C#N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E22 compound treatment 1053319.0 304000.0 0.64 886348.0 225000.0 0.51 0.8171 0.9934 1691043 Maybridge3_005742 Fc1ccccc1C2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E23 mock treatment 834781.0 85500.0 0.18 744421.0 82900.0 0.19 0.2613 0.9998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 E24 mock treatment 640509.0 -109000.0 -0.23 469627.0 -192000.0 -0.44 -0.4716 -0.9556 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F01 compound treatment 501563.0 -248000.0 -0.53 579182.0 -82400.0 -0.19 -0.5038 -0.9035 2078287 Maybridge3_005743 Cc1cc(NC(=O)C2C(C3CC2C=C3)C(=O)O)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F02 compound treatment 640564.0 -109000.0 -0.23 822311.0 161000.0 0.37 0.0954 0.2208 2078288 Maybridge3_005744 FC(F)(F)Oc1ccc(Nc2cc(=O)oc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F03 compound treatment 840819.0 91500.0 0.19 800041.0 138000.0 0.31 0.3598 0.9729 1667940 Maybridge3_005745 CC(CC(=O)O)CC(=O)Nc1cc(Cl)cc(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F04 compound treatment 914894.0 166000.0 0.35 900127.0 239000.0 0.54 0.6318 0.9778 1235146 Maybridge3_005746 OC1(NC(=O)Cc2ccccc2)C(=O)c3ccccc3C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F05 compound treatment 944647.0 195000.0 0.41 768742.0 107000.0 0.24 0.4651 0.968 2078289 Maybridge3_005747 OC(=O)CCCC(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F06 compound treatment 964456.0 215000.0 0.46 771673.0 110000.0 0.25 0.4995 0.9601 2078290 Maybridge3_005748 FC(F)(F)Oc1ccc(Nc2nc(=O)oc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F07 compound treatment 1272761.0 523000.0 1.11 806754.0 145000.0 0.33 1.0181 0.8794 1159841 Maybridge3_005749 O=C1CSC(N1CC2CC2)c3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F08 compound treatment 937920.0 189000.0 0.4 875969.0 214000.0 0.49 0.6274 0.9952 2078291 Maybridge3_005750 OC(=O)CCC(=O)Nc1ccc(OC(F)(F)F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F09 compound treatment 1080384.0 331000.0 0.7 871392.0 210000.0 0.48 0.8336 0.9823 2078292 Maybridge3_005751 CSc1cc(n[nH]1)c2csc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F10 compound treatment 1417959.0 669000.0 1.42 844692.0 183000.0 0.42 1.2968 0.8777 1034515 Maybridge3_005752 Cc1cc(C)cc(c1)N2C(=O)C=CC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F11 compound treatment 908936.0 160000.0 0.34 895002.0 233000.0 0.53 0.6146 0.9764 2078293 Maybridge3_005753 CC1SC(N(C1=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F12 compound treatment 1645986.0 897000.0 1.9 1295863.0 634000.0 1.44 2.3639 0.9907 1501573 Maybridge3_005754 Fc1ccc(CNC(=O)Cc2cc3ccccc3o2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F13 compound treatment 1646559.0 897000.0 1.9 1216332.0 555000.0 1.26 2.2369 0.9801 1271816 Maybridge3_005755 COc1ccccc1c2oc3ccccc3c(=O)c2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F14 compound treatment 1534274.0 785000.0 1.66 1013778.0 352000.0 0.8 1.7429 0.9438 1383539 Maybridge3_005756 O=C1COCC(=O)N1CCc2c[nH]c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F15 compound treatment 943039.0 194000.0 0.41 1223402.0 562000.0 1.28 1.1937 0.8896 1590035 Maybridge3_005757 O=C(Oc1cccc2C(=O)CCc21)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F16 compound treatment 1483802.0 734000.0 1.56 920457.0 259000.0 0.59 1.5173 0.9115 2078294 Maybridge3_005758 CC(=O)Oc1nc(c2ccc(cc2)C(C)(C)C)n(n1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F17 compound treatment 1323931.0 575000.0 1.22 878956.0 217000.0 0.49 1.2109 0.9211 1383926 Maybridge3_005759 COc1ccc(Cl)cc1NC(=O)CC(C)(C)CC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F18 compound treatment 1365342.0 616000.0 1.31 1054443.0 393000.0 0.89 1.5551 0.9828 1184032 Maybridge3_005760 CC1OCN(Cn2c1nc3ccccc23)c4ccc(F)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F19 compound treatment 1340186.0 591000.0 1.25 951362.0 290000.0 0.66 1.3517 0.955 1655485 Maybridge3_005761 Ic1ccc(NC(C#N)c2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F20 compound treatment 1177315.0 428000.0 0.91 851329.0 190000.0 0.43 0.9467 0.9422 2078295 Maybridge3_005762 N=C1NC(=O)C(CC(=O)Nc2cccc3ccccc23)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F21 compound treatment 1255821.0 507000.0 1.07 808939.0 147000.0 0.34 0.9962 0.8856 2078296 Maybridge3_005763 OC(=O)/C=C/C(=O)Nc1ccccc1OC(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F22 compound treatment 1119990.0 371000.0 0.79 784347.0 123000.0 0.28 0.7531 0.903 1257187 Maybridge3_005764 CC(C)(C)c1ccc(cc1)N2C(=O)CC(CC=C)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F23 mock treatment 955211.0 206000.0 0.44 641494.0 -20100.0 -0.05 0.2764 0.6298 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 F24 mock treatment 481554.0 -268000.0 -0.57 466150.0 -195000.0 -0.44 -0.7155 -0.9926 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G01 compound treatment 707977.0 -41300.0 -0.09 711308.0 49800.0 0.11 0.018 0.126 1317800 Maybridge3_005765 Clc1ccc(cc1)c2nnc(o2)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G02 compound treatment 976220.0 227000.0 0.48 856627.0 195000.0 0.44 0.6538 0.9992 2078297 Maybridge3_005766 O=C1C=CC(=O)N1c2ccc3OCCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G03 compound treatment 799397.0 50100.0 0.11 907610.0 246000.0 0.56 0.4707 0.8266 1058235 Maybridge3_005767 COc1ccc(CNc2ccccc2C(=O)O)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G04 compound treatment 1099830.0 351000.0 0.74 1000461.0 339000.0 0.77 1.0703 0.9998 2078298 Maybridge3_005768 COc1ccc(CSC(=N)Nc2ccccc2Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G05 compound treatment 1149093.0 400000.0 0.85 1121950.0 460000.0 1.05 1.3394 0.9945 2078299 Maybridge3_005769 CCO/C=C/1\SC(=S)N(Cc2ccccc2)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G06 compound treatment 106057.0 -643000.0 -1.36 120610.0 -541000.0 -1.23 -1.8339 -0.9987 1524297 Maybridge3_005770 CC(NCc1ccccc1)c2ccccc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G07 compound treatment 1028776.0 279000.0 0.59 1119685.0 458000.0 1.04 1.1554 0.9642 2078300 Maybridge3_005771 CCOc1ccccc1/N=C\2/NCCS2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G08 compound treatment 1205272.0 456000.0 0.97 1204592.0 543000.0 1.23 1.5565 0.9927 1476079 Maybridge3_005772 CC1=CCC2C(C1)C(=O)N(C2=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G09 compound treatment 1355373.0 606000.0 1.28 1193078.0 532000.0 1.21 1.763 0.9995 2078301 Maybridge3_005773 CO/C=C/1\SC(=S)N(CCc2ccccc2)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G10 compound treatment 1485281.0 736000.0 1.56 1480480.0 819000.0 1.86 2.4198 0.9961 2078302 Maybridge3_005774 CCOC(=O)c1cccc(CSC(=N)N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G11 compound treatment 1499210.0 750000.0 1.59 1294154.0 633000.0 1.44 2.1411 0.9988 2078303 Maybridge3_005775 O=C(CC(C#N)c1ccccc1)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G12 compound treatment 1355877.0 607000.0 1.29 1459825.0 798000.0 1.81 2.1926 0.9858 1728358 Maybridge3_005776 O=C1CSC(N1Cc2ccc3OCOc3c2)c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G13 compound treatment 1434451.0 685000.0 1.45 1543943.0 882000.0 2.01 2.4456 0.9874 2078304 Maybridge3_005777 COC(=O)c1ccccc1NC2=NCCS2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G14 compound treatment 1339933.0 591000.0 1.25 1526640.0 865000.0 1.97 2.2761 0.9762 2078305 Maybridge3_005778 CC1(NC(=O)CS1)c2ccc(Br)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G15 compound treatment 1412763.0 663000.0 1.41 1333775.0 672000.0 1.53 2.0752 0.9991 2078306 Maybridge3_005779 O=C1C=CC(=O)N1c2ccc3scnc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G16 compound treatment 1449229.0 700000.0 1.48 1354009.0 692000.0 1.57 2.1624 0.9996 1151798 Maybridge3_005780 COc1cc(cc(OC)c1OC)C(CC#N)CC#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G17 compound treatment 1689333.0 940000.0 1.99 1202663.0 541000.0 1.23 2.279 0.9731 2078307 Maybridge3_005781 Clc1cc(Br)ccc1Nc2n[nH]c(=S)s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G18 compound treatment 1374473.0 625000.0 1.33 1257498.0 596000.0 1.35 1.8952 0.9999 2078308 Maybridge3_005782 CCC(C)c1ccc(cc1)N2C(=O)C=CC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G19 compound treatment 1341891.0 593000.0 1.26 1315923.0 654000.0 1.49 1.9403 0.9965 2078309 Maybridge3_005783 Cc1ccc(C)c(/N=C/c2ccccc2O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G20 compound treatment 1334729.0 585000.0 1.24 1326265.0 665000.0 1.51 1.9462 0.9952 1713859 Maybridge3_005784 Clc1ccc(CCNc2n[nH]c(=S)s2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G21 compound treatment 1121242.0 372000.0 0.79 1114323.0 453000.0 1.03 1.2854 0.9913 2078310 Maybridge3_005785 CC(C)c1ccccc1NC2=NCCS2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G22 compound treatment 1148129.0 399000.0 0.85 935227.0 274000.0 0.62 1.0378 0.9886 2078311 Maybridge3_005786 Cc1ccc(/C=N/C(=C(\N)/C#N)/C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G23 mock treatment 1016229.0 267000.0 0.57 925228.0 264000.0 0.6 0.824 0.9996 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 G24 mock treatment 668940.0 -80400.0 -0.17 461317.0 -200000.0 -0.46 -0.4424 -0.9101 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H01 compound treatment 675844.0 -73500.0 -0.16 766661.0 105000.0 0.24 0.0589 0.2063 2078312 Maybridge3_005787 OC(=O)/C=C/C(=O)NCC1CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H02 compound treatment 1149891.0 401000.0 0.85 1035485.0 374000.0 0.85 1.2016 1.0 2078313 Maybridge3_005788 Cc1ccc(N/C=C/2\C(=O)N(C(c3cccnc3)S2(=O)=O)c4ccc(F)cc4F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H03 compound treatment 1152608.0 403000.0 0.85 929230.0 268000.0 0.61 1.0349 0.9861 1397380 Maybridge3_005789 CC(CC(=O)O)CC(=O)Nc1cc(C)on1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H04 compound treatment 1189160.0 440000.0 0.93 944720.0 283000.0 0.64 1.1146 0.9836 1474311 Maybridge3_005790 CC1(C)COC(=N1)c2ccccc2CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H05 compound treatment 1060196.0 311000.0 0.66 1021767.0 360000.0 0.82 1.0451 0.9942 1715379 Maybridge3_005791 CC(=O)SC1CC(=O)N(C1=O)c2c(C)cccc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H06 compound treatment 1094099.0 345000.0 0.73 1122290.0 461000.0 1.05 1.2576 0.9845 1365999 Maybridge3_005792 CCOC(=O)C(C)c1ccc2cc(OC)ccc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H07 compound treatment 1033055.0 284000.0 0.6 1222600.0 561000.0 1.28 1.3273 0.9412 1273308 Maybridge3_005793 CCC(C)(CC(=O)O)CC(=O)Nc1ccc(Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H08 compound treatment 1399089.0 650000.0 1.38 1471262.0 810000.0 1.84 2.2758 0.9898 2078314 Maybridge3_005794 FC(F)(F)Oc1ccc(cc1)N2C(=O)CCC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H09 compound treatment 1503414.0 754000.0 1.6 1529549.0 868000.0 1.97 2.5259 0.9945 2078315 Maybridge3_005795 CCOC(=O)Sc1ccc2ccccc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H10 compound treatment 1471411.0 722000.0 1.53 1353043.0 691000.0 1.57 2.1941 0.9999 2078316 Maybridge3_005796 Oc1ccccc1/C=N/Cc2csc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H11 compound treatment 1659173.0 910000.0 1.93 1361663.0 700000.0 1.59 2.4894 0.9954 1172116 Maybridge3_005797 COc1ccc(CN2C(SC(C)C2=O)c3cccnc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H12 compound treatment 1811959.0 1060000.0 2.25 1699003.0 1040000.0 2.36 3.2608 0.9997 2078317 Maybridge3_005798 Cc1ccc2oc(nc2c1)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H13 compound treatment 1563816.0 815000.0 1.73 1540962.0 879000.0 2.0 2.6348 0.9973 2078318 Maybridge3_005799 COc1ccc(CC(=O)NCc2cccc(Cl)c2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H14 compound treatment 1625394.0 876000.0 1.86 1791884.0 1130000.0 2.57 3.1305 0.9873 2078319 Maybridge3_005800 COc1ccc(CNC(=O)/C=C/C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H15 compound treatment 1537425.0 788000.0 1.67 1555917.0 894000.0 2.03 2.6192 0.9952 2078320 Maybridge3_005801 FC(F)(F)c1ccc(cc1)N2C(c3ccccn3)S(=O)(=O)CC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H16 compound treatment 1720121.0 971000.0 2.06 1301230.0 640000.0 1.45 2.4837 0.9855 2078321 Maybridge3_005802 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccccc3)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H17 compound treatment 1599375.0 850000.0 1.8 1621696.0 960000.0 2.18 2.8178 0.9955 2078322 Maybridge3_005803 COc1ccc(Cl)cc1NC(=O)COCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H18 compound treatment 1561532.0 812000.0 1.72 1470329.0 809000.0 1.84 2.5178 0.9995 1357039 Maybridge3_005804 COc1ccc(cc1)N2COC(C)c3nc4ccccc4n3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H19 compound treatment 1318834.0 570000.0 1.21 1439548.0 778000.0 1.77 2.1045 0.9827 1162213 Maybridge3_005805 CSc1cccc(NC(C#N)c2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H20 compound treatment 1073515.0 324000.0 0.69 1017676.0 356000.0 0.81 1.0585 0.9967 2078323 Maybridge3_005806 CSc1nnc(/N=C/c2ccccc2O)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H21 compound treatment 1200121.0 451000.0 0.96 975032.0 313000.0 0.71 1.1797 0.9896 2078324 Maybridge3_005807 FC(F)(F)Oc1ccccc1N2C(=O)C=CC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H22 compound treatment 1202438.0 453000.0 0.96 900006.0 238000.0 0.54 1.0626 0.9633 2078325 Maybridge3_005808 FC(F)(F)c1ccc(cc1)N2C(=O)CC(CC=C)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H23 mock treatment 1095533.0 346000.0 0.73 923717.0 262000.0 0.6 0.9405 0.9947 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 H24 mock treatment 498107.0 -251000.0 -0.53 584415.0 -77100.0 -0.18 -0.5006 -0.8928 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I01 compound treatment 822774.0 73500.0 0.16 731511.0 70000.0 0.16 0.2226 0.9999 2078326 Maybridge3_005809 Ic1ccc(Nc2n[nH]c(=S)s2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I02 compound treatment 1361291.0 612000.0 1.3 1348043.0 686000.0 1.56 2.021 0.9958 1585685 Maybridge3_005810 Nc1ccccc1SC2CC(=O)N(C2=O)c3ccc4OCCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I03 compound treatment 1282200.0 533000.0 1.13 1239513.0 578000.0 1.31 1.728 0.9972 2078327 Maybridge3_005811 COc1ccc(/C=C(/NC(=O)c2ccccc2)\C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I04 compound treatment 1156104.0 407000.0 0.86 1279807.0 618000.0 1.41 1.6037 0.9725 2078328 Maybridge3_005812 CCN(CC)C(=S)Oc1ccc(Cl)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I05 compound treatment 1309766.0 560000.0 1.19 1654285.0 993000.0 2.26 2.4361 0.9551 1004834 Maybridge3_005813 COc1ccc(cc1)N2C(=O)CSC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I06 compound treatment 1427535.0 678000.0 1.44 1330511.0 669000.0 1.52 2.0921 0.9996 2078329 Maybridge3_005814 Cc1onc(c1C(=O)N2C=Cc3ccccc3C2C#N)c4ccccc4Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I07 compound treatment 1259773.0 510000.0 1.08 1560855.0 899000.0 2.04 2.211 0.9557 1546147 Maybridge3_005815 Cc1ccccc1c2nc3cc(Cl)ccc3c(=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I08 compound treatment 1566421.0 817000.0 1.73 1529838.0 868000.0 1.97 2.6208 0.9979 1685517 Maybridge3_005816 COc1ccc(Br)c(c1)c2nc3ccccc3c(=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I09 compound treatment 1871812.0 1120000.0 2.38 1392887.0 731000.0 1.66 2.8584 0.9846 2078330 Maybridge3_005817 Cc1onc(c1c2nnnn2c3ccccc3)c4ccccc4Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I10 compound treatment 1676239.0 927000.0 1.97 1530382.0 869000.0 1.98 2.7863 1.0 1071312 Maybridge3_005818 COc1ccc(Nc2cccc(Cl)c2)c(c1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I11 compound treatment 1616834.0 868000.0 1.84 1448324.0 787000.0 1.79 2.5653 0.9999 1181592 Maybridge3_005819 CCOC(=O)c1ccc(cc1)N2C(=O)CC(Sc3ccc(C)cc3)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I12 compound treatment 1762116.0 1010000.0 2.15 1906839.0 1250000.0 2.83 3.5202 0.9907 2078331 Maybridge3_005820 OC(=O)/C=C/C(=O)NCc1cccs1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I13 compound treatment 1529311.0 780000.0 1.65 1367763.0 706000.0 1.61 2.3046 0.9999 2078332 Maybridge3_005821 COC(=O)c1ccccc1NC(=O)/C=C/C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I14 compound treatment 1753281.0 1000000.0 2.13 1522381.0 861000.0 1.96 2.8889 0.9991 1522974 Maybridge3_005822 OC(=O)CC(CC(=O)O)c1ccc(Cl)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I15 compound treatment 1917375.0 1170000.0 2.48 1267078.0 606000.0 1.38 2.7244 0.9616 2078333 Maybridge3_005823 O=C(c1ccccc1)c2ccccc2N3C(=O)C=CC3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I16 compound treatment 1786257.0 1040000.0 2.2 1810353.0 1150000.0 2.61 3.4013 0.9963 1455388 Maybridge3_005824 Cc1ccc2nc(oc(=O)c2c1)c3cc4ccccc4o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I17 compound treatment 1391165.0 642000.0 1.36 1402460.0 741000.0 1.68 2.1533 0.9944 1113873 Maybridge3_005825 Clc1ccc(cc1)C2OC(=O)c3ccccc3S2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I18 compound treatment 1018139.0 269000.0 0.57 1611049.0 949000.0 2.16 1.9294 0.8642 2078334 Maybridge3_005826 O=C1C=CC(=O)N1c2cccc(C#N)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I19 compound treatment 1305508.0 556000.0 1.18 1460788.0 799000.0 1.82 2.1186 0.9781 2078335 Maybridge3_005827 Cc1cccc(Cl)c1N/2C(=O)C(CC(=O)O)S\C2=N/C3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I20 compound treatment 1469797.0 720000.0 1.53 1397804.0 736000.0 1.67 2.2637 0.999 2078336 Maybridge3_005828 Fc1ccc(NC(=O)c2ccccc2I)c(F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I21 compound treatment 1300624.0 551000.0 1.17 1395155.0 734000.0 1.67 2.0058 0.9849 2078337 Maybridge3_005829 FC(F)(F)c1ccc(cc1)N2C(=O)C=CC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I22 compound treatment 1394904.0 646000.0 1.37 1330392.0 669000.0 1.52 2.043 0.9986 1722086 Maybridge3_005830 O=C(CC1OC(=O)c2ccccc12)c3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I23 mock treatment 1118608.0 369000.0 0.78 1106489.0 445000.0 1.01 1.2689 0.992 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 I24 mock treatment 491934.0 -257000.0 -0.55 701828.0 40300.0 0.09 -0.3211 -0.5803 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J01 compound treatment 647118.0 -102000.0 -0.22 862341.0 201000.0 0.46 0.1696 0.3357 1201263 Maybridge3_005831 O=C1CSCC(=O)N1c2cccc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J02 compound treatment 943769.0 194000.0 0.41 1084143.0 423000.0 0.96 0.9709 0.9286 1416459 Maybridge3_005832 Fc1ccc(Nc2cc(=O)oc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J03 compound treatment 962123.0 213000.0 0.45 1140658.0 479000.0 1.09 1.0892 0.9239 1276888 Maybridge3_005833 CC(CC(=O)O)CC(=O)Nc1ccc(F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J04 compound treatment 1159754.0 410000.0 0.87 1192642.0 531000.0 1.21 1.4691 0.9871 1266631 Maybridge3_005834 Clc1ccc(CNC(=C2C(=O)c3ccccc3C2=O)C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J05 compound treatment 1275953.0 527000.0 1.12 1139186.0 478000.0 1.09 1.5573 0.9999 2078338 Maybridge3_005835 Fc1ccc(N2C(=O)COCC2=O)c(F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J06 compound treatment 1110780.0 361000.0 0.77 1260116.0 599000.0 1.36 1.5041 0.9631 1456556 Maybridge3_005836 COc1ccc2cc(ccc2c1)C(C)C(=O)NCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J07 compound treatment 1455594.0 706000.0 1.5 1413707.0 752000.0 1.71 2.2679 0.9978 1195036 Maybridge3_005837 CNc1nnc(SCc2csc3ccccc23)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J08 compound treatment 1711677.0 962000.0 2.04 1523462.0 862000.0 1.96 2.8283 0.9998 2078339 Maybridge3_005838 N#CCC1(C#N)C2CC3CC(C2)CC1C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J09 compound treatment 1762962.0 1010000.0 2.15 1534445.0 873000.0 1.98 2.9228 0.9992 1674973 Maybridge3_005839 OC(=O)CCSc1ccc2ccccc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J10 compound treatment 1695262.0 946000.0 2.01 1634170.0 973000.0 2.21 2.9816 0.9988 2078340 Maybridge3_005840 COC(=O)/C(=C\1/C(=O)Nc2ccccc12)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J11 compound treatment 1777543.0 1030000.0 2.18 1702801.0 1040000.0 2.37 3.2153 0.9992 1500768 Maybridge3_005841 OC(=O)C(C1Sc2ccccc2NC1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J12 compound treatment 2085296.0 1340000.0 2.83 1935949.0 1270000.0 2.9 4.0515 0.9999 2078341 Maybridge3_005842 Fc1ccc(cc1)c2nc3cc(Cl)ccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J13 compound treatment 1123225.0 374000.0 0.79 1586580.0 925000.0 2.1 2.0476 0.9111 2078342 Maybridge3_005843 COc1cc(=O)oc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J14 compound treatment 1724140.0 975000.0 2.07 1812343.0 1150000.0 2.62 3.3114 0.9932 2078343 Maybridge3_005844 COc1ccc(CN2C(=O)C=CC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J15 compound treatment 1152195.0 403000.0 0.85 1667916.0 1010000.0 2.29 2.2218 0.9097 1383942 Maybridge3_005845 NC(=O)c1ccccc1NC(=O)C2C(C3CC2C=C3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J16 compound treatment 1648196.0 899000.0 1.91 1639728.0 978000.0 2.22 2.92 0.997 1682643 Maybridge3_005846 CC(C)Cc1ccc(cc1)C2=CC(C(C(=O)N)C(=O)N2)c3ccc(C#N)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J17 compound treatment 1012458.0 263000.0 0.56 1184997.0 523000.0 1.19 1.236 0.9404 2078344 Maybridge3_005847 COc1ccc(Cl)cc1N2C(=O)COCC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J18 compound treatment 1866383.0 1120000.0 2.37 1563352.0 902000.0 2.05 3.1243 0.9974 2078345 Maybridge3_005848 Clc1cc(Cl)cc(c1)N2C(=C)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J19 compound treatment 1376971.0 628000.0 1.33 1080073.0 419000.0 0.95 1.6137 0.9865 2078346 Maybridge3_005849 Clc1ccc(cc1)C(=O)CC(C#N)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J20 compound treatment 1378772.0 629000.0 1.33 1109585.0 448000.0 1.02 1.6639 0.9911 2078347 Maybridge3_005850 FC(F)(F)c1ccc(NC2=NCCCS2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J21 compound treatment 1332291.0 583000.0 1.24 1107941.0 446000.0 1.01 1.5915 0.9952 2078348 Maybridge3_005851 CC1CC(=O)N(C1=O)c2ccccc2OC(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J22 compound treatment 1066846.0 318000.0 0.67 877094.0 216000.0 0.49 0.8225 0.9878 2078349 Maybridge3_005852 CC(C)(C)C(=O)CSc1nc(c(C#N)c(=O)[nH]1)c2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J23 mock treatment 1095993.0 347000.0 0.73 841443.0 180000.0 0.41 0.8089 0.9617 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 J24 mock treatment 724292.0 -25000.0 -0.05 598210.0 -63300.0 -0.14 -0.1393 -0.9079 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K01 compound treatment 556508.0 -193000.0 -0.41 615449.0 -46100.0 -0.1 -0.3631 -0.8606 2078350 Maybridge3_005853 C1CN=C(NC2CCCCC2)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K02 compound treatment 512827.0 -236000.0 -0.5 500555.0 -161000.0 -0.37 -0.6133 -0.9881 2071140 Maybridge3_005854 Cc1cc(C)c(CSC(=N)N)c(C)c1CSC(=N)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K03 compound treatment 954957.0 206000.0 0.44 942647.0 281000.0 0.64 0.7602 0.9826 2078351 Maybridge3_005855 Cc1ccc(/N=C\2/NCCS2)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K04 compound treatment 871836.0 123000.0 0.26 810105.0 149000.0 0.34 0.4225 0.9916 2078352 Maybridge3_005856 C1CN=C(NC2CC3CC2C4C=CCC34)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K05 compound treatment 1151244.0 402000.0 0.85 1211806.0 550000.0 1.25 1.4871 0.9825 1368985 Maybridge3_005857 Cc1ccc(Cl)cc1N2C(=O)CC(Sc3ccccc3N)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K06 compound treatment 1286744.0 537000.0 1.14 1492102.0 831000.0 1.89 2.1409 0.9707 2078353 Maybridge3_005858 CC(=O)NC1=CC(=O)CC(C)(C)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K07 compound treatment 1227170.0 478000.0 1.01 1362208.0 701000.0 1.59 1.8427 0.9761 1083077 Maybridge3_005859 CSc1cccc(c1)N2C(=O)C=CC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K08 compound treatment 1343388.0 594000.0 1.26 1240038.0 578000.0 1.32 1.8205 0.9998 1230292 Maybridge3_005860 O=C1C(=C(NCc2cccnc2)C#N)C(=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K09 compound treatment 1400984.0 652000.0 1.38 1246347.0 585000.0 1.33 1.917 0.9998 1209524 Maybridge3_005861 COc1cc(cc(OC)c1OC)c2noc(C)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K10 compound treatment 1491999.0 743000.0 1.57 1255808.0 594000.0 1.35 2.0687 0.9971 1064487 Maybridge3_005862 CN(C)C(=O)c1ccc(cc1)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K11 compound treatment 1691624.0 942000.0 2.0 1274433.0 613000.0 1.39 2.3979 0.9845 2078354 Maybridge3_005863 Cc1ccc(NC(=O)C(F)(F)F)c(c1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K12 compound treatment 1392651.0 643000.0 1.36 1700101.0 1040000.0 2.36 2.634 0.966 2078355 Maybridge3_005864 O=C1C=CC(=O)N1Cc2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K13 compound treatment 1685833.0 937000.0 1.99 1209454.0 548000.0 1.25 2.2847 0.9748 1070150 Maybridge3_005865 COC(=O)c1ccccc1N2C(=O)C=CC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K14 compound treatment 1685834.0 937000.0 1.99 1415875.0 754000.0 1.71 2.6166 0.9973 1630954 Maybridge3_005866 Cc1ccc2nc(oc(=O)c2c1)c3ccccc3F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K15 compound treatment 1881318.0 1130000.0 2.4 1327530.0 666000.0 1.51 2.7676 0.9753 2078356 Maybridge3_005867 O=C1C=CC(=O)N1Cc2ccc3OCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K16 compound treatment 1835669.0 1090000.0 2.3 1149222.0 488000.0 1.11 2.4125 0.9438 1462549 Maybridge3_005868 CC1CN(CC(C)O1)c2ccccc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K17 compound treatment 1489336.0 740000.0 1.57 1223396.0 562000.0 1.28 2.0126 0.9948 2078357 Maybridge3_005869 COc1cc(cc(OC)c1OC)C2OC(=O)c3ccccc3S2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K18 compound treatment 1365783.0 616000.0 1.31 1373102.0 712000.0 1.62 2.068 0.9944 1286809 Maybridge3_005870 O=C1CCC(=O)N1c2ccc(cc2)C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K19 compound treatment 1543011.0 794000.0 1.68 1246826.0 585000.0 1.33 2.1307 0.9932 2078358 Maybridge3_005871 OC(=O)/C=C/C(=O)Nc1ccnn1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K20 compound treatment 1421808.0 672000.0 1.43 1123574.0 462000.0 1.05 1.7509 0.9887 2078359 Maybridge3_005872 Clc1ccc(CCN2C(SCCC2=O)c3cccnc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K21 compound treatment 1311293.0 562000.0 1.19 1065634.0 404000.0 0.92 1.4921 0.9918 2078360 Maybridge3_005873 Fc1cccc(c1)n2nnnc2c3ccc(Cl)c(Cl)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K22 compound treatment 1144701.0 395000.0 0.84 945401.0 284000.0 0.65 1.049 0.9917 1556396 Maybridge3_005874 Cc1ccc(cc1)C2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K23 mock treatment 1052268.0 303000.0 0.64 777665.0 116000.0 0.26 0.6408 0.9228 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 K24 mock treatment 601944.0 -147000.0 -0.31 467998.0 -194000.0 -0.44 -0.5321 -0.9859 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L01 compound treatment 613863.0 -135000.0 -0.29 557067.0 -104000.0 -0.24 -0.371 -0.9956 1516643 Maybridge3_005875 Cc1cc(Cl)ccc1NC(=O)COCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L02 compound treatment 840092.0 90800.0 0.19 836377.0 175000.0 0.4 0.4171 0.9446 2078361 Maybridge3_005876 Cc1cc(C)c(c(C)c1)n2nnnc2SCC(=O)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L03 compound treatment 832514.0 83200.0 0.18 903935.0 242000.0 0.55 0.5144 0.889 1576657 Maybridge3_005877 CC(CC(=O)O)CC(=O)Nc1ccc(Cl)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L04 compound treatment 847895.0 98600.0 0.21 931863.0 270000.0 0.61 0.5823 0.8971 1332546 Maybridge3_005878 CCOC(=O)N1C(C=Cc2cc(ccc12)C(C)C)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L05 compound treatment 886163.0 137000.0 0.29 1073318.0 412000.0 0.94 0.8671 0.8847 2078362 Maybridge3_005879 CC(=O)Nc1ccc(cc1)C2=N/C(=C/c3cc(Br)cs3)/C(=O)O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L06 compound treatment 1148054.0 399000.0 0.85 1090251.0 429000.0 0.97 1.2869 0.9975 2078363 Maybridge3_005880 CCOC(=O)/C(=C/1\CCCc2cc(OC)ccc12)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L07 compound treatment 961579.0 212000.0 0.45 1144952.0 483000.0 1.1 1.0953 0.9223 2078364 Maybridge3_005881 Cc1ccc(NC(=C2C(=O)c3ccccc3C2=O)C#N)cc1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L08 compound treatment 1054670.0 305000.0 0.65 1138835.0 477000.0 1.09 1.225 0.9695 2078365 Maybridge3_005882 CCOc1nc2ccc(C)cc2c(=O)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L09 compound treatment 880841.0 132000.0 0.28 1181882.0 520000.0 1.18 1.0337 0.8505 2078366 Maybridge3_005883 COc1ccc(/C=C\2/N=C(OC2=O)c3ccccc3)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L10 compound treatment 990533.0 241000.0 0.51 1073646.0 412000.0 0.94 1.0241 0.9594 2078367 Maybridge3_005884 O=C1CC(Sc2cccs2)C(=O)N1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L11 compound treatment 1087207.0 338000.0 0.72 1227938.0 566000.0 1.29 1.4171 0.9617 2078368 Maybridge3_005885 OC(=O)/C=C/C(=O)NCc1csc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L12 compound treatment 1526637.0 777000.0 1.65 1482698.0 821000.0 1.87 2.4854 0.9981 2078369 Maybridge3_005886 Cc1ccc2oc(nc2c1)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L13 compound treatment 1351079.0 602000.0 1.28 1163820.0 502000.0 1.14 1.7095 0.9985 1438301 Maybridge3_005887 OC(=O)C1C(C2OC1C=C2)C(=O)NCc3cccc(Cl)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L14 compound treatment 1834804.0 1090000.0 2.3 1280469.0 619000.0 1.41 2.6222 0.9721 2078370 Maybridge3_005888 COc1ccccc1CNC(=O)/C=C/C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L15 compound treatment 1333879.0 585000.0 1.24 1212997.0 551000.0 1.25 1.7628 1.0 1523047 Maybridge3_005889 Fc1ccc(NC(=O)Cc2csc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L16 compound treatment 1089667.0 340000.0 0.72 1024598.0 363000.0 0.83 1.0939 0.9978 2078371 Maybridge3_005890 COc1ccc(cc1)C2C(=C(N)OC3=C2C(=O)CC(C3)c4ccccc4)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L17 compound treatment 1241712.0 492000.0 1.04 1058270.0 397000.0 0.9 1.3759 0.9974 1377837 Maybridge3_005891 COc1cc(OC)cc(c1)N2C(=O)CSCC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L18 compound treatment 1495696.0 746000.0 1.58 878139.0 217000.0 0.49 1.4671 0.8853 2078372 Maybridge3_005892 Fc1ccc(/C=C(\C#N)/c2csc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L19 compound treatment 1761463.0 1010000.0 2.15 1102549.0 441000.0 1.0 2.2262 0.94 2078373 Maybridge3_005893 Fc1ccc(C=C2C(=O)c3ccccc3C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L20 compound treatment 1524491.0 775000.0 1.64 971220.0 310000.0 0.7 1.6599 0.9284 1698353 Maybridge3_005894 COc1cccc(c1)c2c(C#N)c(=O)[nH]c3CCc4cc(OC)ccc4-c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L21 compound treatment 1469143.0 720000.0 1.53 953202.0 292000.0 0.66 1.5479 0.9303 2078374 Maybridge3_005895 OCC1(CO)CSC(=N1)Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L22 compound treatment 1357688.0 608000.0 1.29 957862.0 296000.0 0.67 1.3883 0.9541 2078375 Maybridge3_005896 CC(C)(C)c1ccc(NC(=C2C(=O)c3ccccc3C2=O)C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L23 mock treatment 1255631.0 506000.0 1.07 736433.0 74900.0 0.17 0.8794 0.8091 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 L24 mock treatment 496126.0 -253000.0 -0.54 566014.0 -95500.0 -0.22 -0.5331 -0.9207 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M01 compound treatment 380083.0 -369000.0 -0.78 352249.0 -309000.0 -0.7 -1.0507 -0.9986 2078376 Maybridge3_005897 CC1CC(CC(C)(C)C1)/N=C\2/NCCS2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M02 compound treatment 1015084.0 266000.0 0.56 1004416.0 343000.0 0.78 0.9496 0.9873 2078377 Maybridge3_005898 O=C1C=CC(=O)N1c2ccccc2N3CCCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M03 compound treatment 871711.0 122000.0 0.26 1047050.0 385000.0 0.88 0.8032 0.8788 1267614 Maybridge3_005899 COc1ccc(CNc2ccc(cc2)C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M04 compound treatment 994131.0 245000.0 0.52 1212567.0 551000.0 1.25 1.2528 0.9239 1015374 Maybridge3_005900 O=C1CSC(=S)N1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M05 compound treatment 936411.0 187000.0 0.4 1207276.0 546000.0 1.24 1.1578 0.8888 2078378 Maybridge3_005901 CCc1cccc(CC)c1NC(=O)/C=C/C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M06 compound treatment 967765.0 218000.0 0.46 1327243.0 666000.0 1.51 1.3977 0.8831 2078379 Maybridge3_005902 OC(=O)CNC(=O)/C=C/c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M07 compound treatment 1120263.0 371000.0 0.79 1107731.0 446000.0 1.01 1.2734 0.9921 2078380 Maybridge3_005903 CCO/C=C/1\SC(=S)N(C1=O)c2ccc(cc2)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M08 compound treatment 987309.0 238000.0 0.5 1207802.0 546000.0 1.24 1.2349 0.9213 2078381 Maybridge3_005904 COc1ccc(Br)c(NC2=NCCS2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M09 compound treatment 1071811.0 323000.0 0.68 1139204.0 478000.0 1.09 1.2513 0.9751 2078382 Maybridge3_005905 CCOC(=O)c1ccc(/N=C/c2ccc(Cl)c(Cl)c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M10 compound treatment 994195.0 245000.0 0.52 1207495.0 546000.0 1.24 1.2448 0.9252 2078383 Maybridge3_005906 OC(=O)/C=C/C(=O)Nc1cccc2CCCCc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M11 compound treatment 1222281.0 473000.0 1.0 974946.0 313000.0 0.71 1.2128 0.986 1048382 Maybridge3_005907 OC(=O)c1ccccc1NC(=O)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M12 compound treatment 1106615.0 357000.0 0.76 1258386.0 597000.0 1.36 1.4951 0.9621 1504168 Maybridge3_005908 O=C(Cc1cccc2ccccc12)NCc3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M13 compound treatment 1044297.0 295000.0 0.63 912649.0 251000.0 0.57 0.8459 0.999 2078384 Maybridge3_005909 OC(=O)/C=C/C(=O)Nc1ccccc1SCc2ccccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M14 compound treatment 1309296.0 560000.0 1.19 1271574.0 610000.0 1.39 1.8201 0.997 2078385 Maybridge3_005910 N/C(=C(/N=C/c1cccc(Cl)c1)\C#N)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M15 compound treatment 1269997.0 521000.0 1.1 886579.0 225000.0 0.51 1.1423 0.9389 2078386 Maybridge3_005911 COc1ccc(NC(=O)/C=C/C(=O)O)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M16 compound treatment 1181822.0 433000.0 0.92 1011950.0 350000.0 0.8 1.2117 0.9975 1312957 Maybridge3_005912 NC(=O)CC(CC(=O)N)c1c(Cl)cccc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M17 compound treatment 1223430.0 474000.0 1.01 1040094.0 379000.0 0.86 1.3193 0.997 2078387 Maybridge3_005913 COc1ccc(NC(=O)/C=C/C(=O)O)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M18 compound treatment 1298438.0 549000.0 1.16 1145940.0 484000.0 1.1 1.6019 0.9996 1710869 Maybridge3_005914 O=C1CCC(=O)N1c2cccc(C#N)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M19 compound treatment 1391153.0 642000.0 1.36 1256413.0 595000.0 1.35 1.9185 1.0 2078388 Maybridge3_005915 Cc1ccc(/C=C\2/SC(=S)N(C2=O)c3ccc(cc3)S(=O)(=O)Nc4nccs4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M20 compound treatment 1468262.0 719000.0 1.52 1293490.0 632000.0 1.44 2.0937 0.9996 2078389 Maybridge3_005916 OC(=O)C1CSC(N1)C2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M21 compound treatment 1415129.0 666000.0 1.41 1055848.0 394000.0 0.9 1.632 0.976 2078390 Maybridge3_005917 FC(F)(F)c1ccc(Nc2n[nH]c(=S)s2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M22 compound treatment 1288478.0 539000.0 1.14 1151215.0 490000.0 1.11 1.5954 0.9999 2078391 Maybridge3_005918 Cc1cc(/N=C/c2ccccc2O)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M23 mock treatment 1239030.0 490000.0 1.04 1012404.0 351000.0 0.8 1.2982 0.9915 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 M24 mock treatment 632471.0 -117000.0 -0.25 649316.0 -12200.0 -0.03 -0.1948 -0.7816 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N01 compound treatment 500766.0 -249000.0 -0.53 630150.0 -31400.0 -0.07 -0.4231 -0.7956 1469510 Maybridge3_005919 OC(=O)COCC(=O)Nc1cccc(C#N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N02 compound treatment 940588.0 191000.0 0.41 1075417.0 414000.0 0.94 0.9521 0.9292 2078392 Maybridge3_005920 O/N=C\1/Cc2ccccc2OC1c3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N03 compound treatment 1175020.0 426000.0 0.9 1031173.0 370000.0 0.84 1.2324 0.9994 1255246 Maybridge3_005921 Clc1ccc(CSC2CC(=O)N(C2=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N04 compound treatment 931985.0 183000.0 0.39 1126206.0 465000.0 1.06 1.0208 0.9073 2078393 Maybridge3_005922 CSc1ccc(/C=C\2/N3CCC(CC3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N05 compound treatment 957142.0 208000.0 0.44 1275711.0 614000.0 1.4 1.2989 0.8871 1432855 Maybridge3_005923 CCOC(=O)c1ccc(NC(=O)CSCC(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N06 compound treatment 1089164.0 340000.0 0.72 1266208.0 605000.0 1.37 1.4815 0.9545 2078394 Maybridge3_005924 N#CCC1(CCCc2ccccc21)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N07 compound treatment 1028168.0 279000.0 0.59 1100261.0 439000.0 1.0 1.1233 0.9688 2078395 Maybridge3_005925 O=C/1OC(=N\C1=C/c2ccsc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N08 compound treatment 1042292.0 293000.0 0.62 1221032.0 559000.0 1.27 1.3386 0.9457 1473393 Maybridge3_005926 CCN1CCC2(CC1)NC(=O)c3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N09 compound treatment 1049268.0 300000.0 0.64 1176910.0 515000.0 1.17 1.2782 0.9588 1185892 Maybridge3_005927 COc1ccc(CNC(=C2C(=O)c3ccccc3C2=O)C#N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N10 compound treatment 1005418.0 256000.0 0.54 1132100.0 471000.0 1.07 1.1404 0.9506 2078396 Maybridge3_005928 FC(F)(F)Oc1ccccc1NCn2nnc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N11 compound treatment 1138814.0 390000.0 0.83 1255453.0 594000.0 1.35 1.5387 0.9722 2078397 Maybridge3_005929 Cc1cc(/C=C/2\N=COC2=O)ccc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N12 compound treatment 1155800.0 406000.0 0.86 1248810.0 587000.0 1.34 1.5534 0.9776 1728896 Maybridge3_005930 Cc1ccnc(c1)N2C(=O)CCC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N13 compound treatment 1259413.0 510000.0 1.08 1231909.0 570000.0 1.3 1.6816 0.9959 2078398 Maybridge3_005931 CCc1cccc(C)c1NC(=C2C(=O)c3ccccc3C2=O)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N14 compound treatment 1207797.0 458000.0 0.97 1100348.0 439000.0 1.0 1.3927 0.9999 2078399 Maybridge3_005932 Cc1ccc(CNC(=O)/C=C/C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N15 compound treatment 1144523.0 395000.0 0.84 1041350.0 380000.0 0.86 1.203 0.9999 2078400 Maybridge3_005933 Clc1cc(Cl)cc(NC(C#N)c2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N16 compound treatment 1113607.0 364000.0 0.77 1090872.0 429000.0 0.98 1.2363 0.9933 2078401 Maybridge3_005934 FC(F)(F)c1ccc(cc1)N2C(=C)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N17 compound treatment 1150746.0 401000.0 0.85 999825.0 338000.0 0.77 1.1456 0.9987 2078402 Maybridge3_005935 COc1cc(OC)cc(/C=C/2\N=C(C)OC2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N18 compound treatment 1290609.0 541000.0 1.15 1169915.0 508000.0 1.16 1.6287 1.0 1415728 Maybridge3_005936 COc1ccccc1CNc2n[nH]c(=S)s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N19 compound treatment 1648895.0 900000.0 1.91 1279015.0 617000.0 1.4 2.3412 0.9886 1710115 Maybridge3_005937 OC(=O)CSC1CC(=O)N(C1=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N20 compound treatment 1260824.0 512000.0 1.08 1152207.0 491000.0 1.12 1.5556 0.9999 1547948 Maybridge3_005938 Fc1ccc(CN2C(c3cccnc3)S(=O)(=O)CC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N21 compound treatment 1569294.0 820000.0 1.74 1227441.0 566000.0 1.29 2.1389 0.989 2078403 Maybridge3_005939 COc1ccc2C(=O)/C(=C/c3ccc(C)o3)/CCc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N22 compound treatment 1355996.0 607000.0 1.29 1131287.0 470000.0 1.07 1.6646 0.9957 2078404 Maybridge3_005940 O=C1C(=C(Nc2ccccc2)C#N)C(=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N23 mock treatment 1307489.0 558000.0 1.18 1056796.0 395000.0 0.9 1.4721 0.9908 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 N24 mock treatment 546614.0 -203000.0 -0.43 609356.0 -52200.0 -0.12 -0.3878 -0.8698 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O01 compound treatment 478552.0 -271000.0 -0.57 568380.0 -93200.0 -0.21 -0.5557 -0.9082 2078405 Maybridge3_005941 CCOc1ccc(/N=C\2/NCCS2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O02 compound treatment 1089755.0 340000.0 0.72 1206098.0 545000.0 1.24 1.3858 0.967 2078406 Maybridge3_005942 CCOc1ccc(cc1)C(=O)CC2OC(=O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O03 compound treatment 207849.0 -541000.0 -1.15 280075.0 -381000.0 -0.87 -1.4249 -0.9904 1071715 Maybridge3_005943 Cc1cc(CSC(=N)N)c(C)cc1CSC(=N)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O04 compound treatment 1195724.0 446000.0 0.95 1437729.0 776000.0 1.76 1.917 0.9573 2078407 Maybridge3_005944 CSc1cccc(c1)N2C(=O)SC(C2=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O05 compound treatment 1247232.0 498000.0 1.06 1410869.0 749000.0 1.7 1.951 0.9735 1340187 Maybridge3_005945 Clc1cccc(c1)c2nc3ccccc3c(=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O06 compound treatment 1470160.0 721000.0 1.53 1542022.0 880000.0 2.0 2.4961 0.9911 1288043 Maybridge3_005946 CCOC(=O)c1ccc(cc1)N2C(SCC2=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O07 compound treatment 1208027.0 459000.0 0.97 1309360.0 648000.0 1.47 1.7291 0.9797 2078408 Maybridge3_005947 CCO/C=C/1\SC(=S)N(C1=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O08 compound treatment 1234058.0 485000.0 1.03 1325538.0 664000.0 1.51 1.7941 0.9824 1435480 Maybridge3_005948 COc1ccc(Br)c(c1)C(=O)NC(C)(C)CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O09 compound treatment 1572168.0 823000.0 1.74 1284510.0 623000.0 1.42 2.235 0.9947 2078409 Maybridge3_005949 COc1cc(cc(OC)c1OC)N2C(=O)CSC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O10 compound treatment 1472411.0 723000.0 1.53 1403235.0 742000.0 1.69 2.2763 0.9989 2078410 Maybridge3_005950 O=C1C=CC(=O)N1c2cccc3CCCCc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O11 compound treatment 1432010.0 683000.0 1.45 1178716.0 517000.0 1.18 1.8548 0.9947 2078411 Maybridge3_005951 C/C(=N\Cc1ccc(C#N)cc1)/c2ccccc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O12 compound treatment 1657827.0 909000.0 1.93 1293795.0 632000.0 1.44 2.3783 0.9896 2078412 Maybridge3_005952 S=c1[nH]nc(NCc2cccs2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O13 compound treatment 1535114.0 786000.0 1.67 1436144.0 775000.0 1.76 2.4232 0.9996 1553751 Maybridge3_005953 COC(=O)c1ccccc1N2C(=O)CC(Sc3ccccc3N)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O14 compound treatment 1347295.0 598000.0 1.27 1467653.0 806000.0 1.83 2.1923 0.9838 2078413 Maybridge3_005954 N/C(=C(/N=C/c1ccccc1)\C#N)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O15 compound treatment 1562894.0 814000.0 1.72 1319956.0 658000.0 1.5 2.2781 0.9975 2078414 Maybridge3_005955 Cc1onc(c1c2nc3ccccc3c(=O)o2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O16 compound treatment 1511307.0 762000.0 1.62 1095995.0 434000.0 0.99 1.8407 0.9721 1459131 Maybridge3_005956 COc1ccc(cc1)c2nc3ccccc3c(=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O17 compound treatment 1338111.0 589000.0 1.25 1214117.0 553000.0 1.26 1.771 1.0 2078415 Maybridge3_005957 CC(C)c1cccc(C(C)C)c1N2C(=O)C=CC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O18 compound treatment 1275058.0 526000.0 1.11 1383540.0 722000.0 1.64 1.9488 0.9822 2078416 Maybridge3_005958 CCCc1ccc(cc1)N2C(=O)CCC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O19 compound treatment 1777196.0 1030000.0 2.18 1257270.0 596000.0 1.35 2.4985 0.9738 2078417 Maybridge3_005959 Cc1cc(C)nc(/N=C/c2ccccc2O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O20 compound treatment 1583081.0 834000.0 1.77 1340847.0 679000.0 1.54 2.3419 0.9977 2078418 Maybridge3_005960 Cc1ccc(Nc2nnc(o2)c3ccccc3N)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O21 compound treatment 1553637.0 804000.0 1.71 1272046.0 610000.0 1.39 2.1872 0.9948 2078419 Maybridge3_005961 Oc1ccccc1/C=N/c2ccc(Oc3ccccc3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O22 compound treatment 1426155.0 677000.0 1.43 1238601.0 577000.0 1.31 1.9423 0.999 2078420 Maybridge3_005962 O=C(NCCc1cccs1)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O23 mock treatment 1060318.0 311000.0 0.66 1022397.0 361000.0 0.82 1.0463 0.9941 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 O24 mock treatment 465495.0 -284000.0 -0.6 505254.0 -156000.0 -0.36 -0.6767 -0.9684 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P01 compound treatment 448020.0 -301000.0 -0.64 490007.0 -172000.0 -0.39 -0.7274 -0.972 2078421 Maybridge3_005963 O=C1CSC(=S)N1CC2CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P02 compound treatment 465790.0 -284000.0 -0.6 579086.0 -82500.0 -0.19 -0.5576 -0.8856 2078422 Maybridge3_005964 Clc1ccc(cc1)C(=O)CC(C(C#N)C#N)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P03 compound treatment 602531.0 -147000.0 -0.31 821807.0 160000.0 0.36 0.0376 0.0785 1507005 Maybridge3_005965 CC(=O)SC1CC(=O)N(C1=O)c2cc(Cl)cc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P04 compound treatment 613765.0 -136000.0 -0.29 845672.0 184000.0 0.42 0.0928 0.1828 2078423 Maybridge3_005966 FC(F)(F)Oc1ccc(NC(=O)C#Cc2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P05 compound treatment 692120.0 -57200.0 -0.12 892935.0 231000.0 0.53 0.2863 0.5302 1331738 Maybridge3_005967 CCOC(=O)c1ccc(cc1)N2C(=O)CSCC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P06 compound treatment 790032.0 40700.0 0.09 937546.0 276000.0 0.63 0.5047 0.7969 2078424 Maybridge3_005968 CCOC(=O)/C(=C/1\CCc2ccccc12)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P07 compound treatment 666549.0 -82800.0 -0.18 824921.0 163000.0 0.37 0.1386 0.3374 2078425 Maybridge3_005969 Oc1ccc(Cl)cc1NC(=C2C(=O)c3ccccc3C2=O)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P08 compound treatment 631948.0 -117000.0 -0.25 708757.0 47200.0 0.11 -0.1 -0.3692 1610166 Maybridge3_005970 Clc1ccc(NC2CC(=O)N(C2=O)c3ccc(Cl)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P09 compound treatment 646026.0 -103000.0 -0.22 694078.0 32500.0 0.07 -0.1025 -0.4437 1620166 Maybridge3_005971 CC(C)(CC(=O)O)CC(=O)Nc1cc(Cl)ccc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P10 compound treatment 723162.0 -26100.0 -0.06 666865.0 5310.0 0.01 -0.0307 -0.5403 2078426 Maybridge3_005972 FC(F)(F)Oc1ccc(NCn2nnc3cc(Cl)ccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P11 compound treatment 812466.0 63200.0 0.13 572650.0 -88900.0 -0.2 -0.0482 -0.199 1544733 Maybridge3_005973 CC(C)(C)c1cccc(c1O)C2(O)C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P12 compound treatment 615165.0 -134000.0 -0.28 549588.0 -112000.0 -0.25 -0.3811 -0.9985 1311154 Maybridge3_005974 OC(=O)COCC(=O)Nc1ccccn1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P13 compound treatment 543697.0 -206000.0 -0.44 509075.0 -152000.0 -0.35 -0.5533 -0.9936 2078427 Maybridge3_005975 Cc1ccc(/C=C/2\SC(=O)N(C2=O)c3ccccc3)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P14 compound treatment 661893.0 -87400.0 -0.19 586733.0 -74800.0 -0.17 -0.2513 -0.9991 1081390 Maybridge3_005976 Cc1ccc(CN2C(=O)C=CC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P15 compound treatment 710138.0 -39200.0 -0.08 704930.0 43400.0 0.1 0.011 0.0855 2078428 Maybridge3_005977 Cc1ccc(Cl)cc1NC(C#N)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P16 compound treatment 711764.0 -37500.0 -0.08 736915.0 75400.0 0.17 0.0649 0.3434 2078429 Maybridge3_005978 Fc1ccc(cc1)N2C(=C)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P17 compound treatment 645030.0 -104000.0 -0.22 714867.0 53300.0 0.12 -0.0706 -0.28 1662322 Maybridge3_005979 Cc1ccc(cc1)S(=O)(=O)NCCc2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P18 compound treatment 462562.0 -287000.0 -0.61 452931.0 -209000.0 -0.47 -0.7652 -0.9925 2078430 Maybridge3_005980 Cc1ccc(CNC2=NCCS2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P19 compound treatment 683378.0 -65900.0 -0.14 766593.0 105000.0 0.24 0.07 0.2531 2078431 Maybridge3_005981 CC(SC1CC(=O)N(C1=O)c2ccccc2)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P20 compound treatment 692290.0 -57000.0 -0.12 720741.0 59200.0 0.13 0.0097 0.0535 2078432 Maybridge3_005982 C=CCOc1ccc(/C=C/2\N3CCC(CC3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P21 compound treatment 561009.0 -188000.0 -0.4 625204.0 -36300.0 -0.08 -0.3407 -0.8358 2078433 Maybridge3_005983 Cc1cc(C)c(NC2=NC(CO)(CO)CS2)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P22 compound treatment 566541.0 -183000.0 -0.39 550710.0 -111000.0 -0.25 -0.4522 -0.9783 2078434 Maybridge3_005984 O=C/1C2CCN(CC2)\C1=C\c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P23 mock treatment 549636.0 -200000.0 -0.42 549654.0 -112000.0 -0.25 -0.4792 -0.9703 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.1447 P24 mock treatment 443113.0 -306000.0 -0.65 482762.0 -179000.0 -0.41 -0.7464 -0.9746 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A01 compound treatment 479063.0 -256000.0 -0.54 360724.0 -400000.0 -0.91 -1.0262 -0.9696 1205993 ChemDiv3_000001 Cc1cc(c(O)c(c1)C(C)(C)C)n2nc3ccc(Cl)cc3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A02 compound treatment 573136.0 -162000.0 -0.34 418019.0 -342000.0 -0.78 -0.7931 -0.9323 1044707 ChemDiv3_000002 OC(=O)c1ccccc1C(=O)c2ccc(cc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A03 compound treatment 760769.0 25800.0 0.05 361440.0 -399000.0 -0.91 -0.6028 -0.6633 1699093 ChemDiv3_000003 Cc1ccc(Nc2ccc3ncnc4-c5ccccc5C(=O)c2c43)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A04 compound treatment 788591.0 53600.0 0.11 456632.0 -304000.0 -0.69 -0.4081 -0.583 3117569 ChemDiv3_000004 Clc1c(sc2ccccc12)C(=O)Nc3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A05 compound treatment 2539697.0 1800000.0 3.83 922079.0 162000.0 0.37 2.9652 0.7715 1561677 ChemDiv3_000005 CCOC(=O)c1c(O)nc2c3ccccc3oc2c1c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A06 compound treatment 839511.0 104000.0 0.22 593684.0 -167000.0 -0.38 -0.1114 -0.2537 3117570 ChemDiv3_000006 CN(C)C(=O)C[n+]1ccc(/C=N/O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A07 compound treatment 614920.0 -120000.0 -0.25 458076.0 -302000.0 -0.69 -0.6661 -0.9087 1166193 ChemDiv3_000007 CCCC1CCC(CC1)c2ccc(cc2)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A08 compound treatment 381309.0 -354000.0 -0.75 249838.0 -511000.0 -1.16 -1.351 -0.9776 3019825 ChemDiv3_000008 C(c1ccccc1)[n+]2ccc(cc2)c3nc4ccccc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A09 compound treatment 372226.0 -363000.0 -0.77 360967.0 -399000.0 -0.91 -1.186 -0.9966 1640201 ChemDiv3_000009 CCCc1ccc(OC(=O)c2ccc(O)cc2Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A10 compound treatment 434155.0 -301000.0 -0.64 443994.0 -316000.0 -0.72 -0.9597 -0.9982 1305993 ChemDiv3_000010 Cc1sc(N)nc1C2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A11 compound treatment 540876.0 -194000.0 -0.41 563758.0 -197000.0 -0.45 -0.6072 -0.9991 3019826 ChemDiv3_000011 CCN1C(=O)/C(=C/C=C\2/Sc3ccccc3N2CC)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A12 compound treatment 509933.0 -225000.0 -0.48 594345.0 -166000.0 -0.38 -0.6044 -0.9933 1005107 ChemDiv3_000012 CC(C)(C)C(=O)C[n+]1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A13 compound treatment 245959.0 -489000.0 -1.04 284259.0 -476000.0 -1.08 -1.4986 -0.9998 1917998 ChemDiv3_000013 CN(C)c1ccc(cc1)c2n(C)c3ccccc3[n+]2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A14 compound treatment 420290.0 -315000.0 -0.67 419697.0 -341000.0 -0.77 -1.0195 -0.9972 3117571 ChemDiv3_000014 O/N=C/c1cc[n+](C/C=C\c2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A15 compound treatment 847380.0 112000.0 0.24 769597.0 9180.0 0.02 0.1832 0.7661 1511477 ChemDiv3_000015 Cc1ccc(cc1)S(=O)(=O)c2ccc(cc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A16 compound treatment 698488.0 -36500.0 -0.08 651116.0 -109000.0 -0.25 -0.2305 -0.8854 1463254 ChemDiv3_000016 C(CN1CCOCC1)Oc2ccc3ccccc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A17 compound treatment 658614.0 -76400.0 -0.16 627903.0 -133000.0 -0.3 -0.3276 -0.9576 1289110 ChemDiv3_000017 N#CC(=c1ccc(=C(C#N)c2ccc(cc2)N3CCCC3)cc1)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A18 compound treatment 543968.0 -191000.0 -0.41 511332.0 -249000.0 -0.57 -0.6868 -0.9865 1594677 ChemDiv3_000018 CC(C)CN(CC(C)C)Cn1c(=O)oc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A19 compound treatment 726632.0 -8380.0 -0.02 550924.0 -209000.0 -0.48 -0.3494 -0.733 1914297 ChemDiv3_000019 COc1ccc(/C=N/n2cnnc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A20 compound treatment 595749.0 -139000.0 -0.3 460131.0 -300000.0 -0.68 -0.6915 -0.9297 1550111 ChemDiv3_000020 CC(C)C1CCC(C)C(C(O)c2ccc(cc2)c3ccccc3)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A21 compound treatment 244348.0 -491000.0 -1.04 253706.0 -507000.0 -1.15 -1.5501 -0.9987 3019827 ChemDiv3_000021 CN(C)c1ccc(/C=C/C=C/c2cc[n+](C)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A22 compound treatment 547831.0 -187000.0 -0.4 379520.0 -381000.0 -0.87 -0.8929 -0.9374 1470588 ChemDiv3_000022 Fc1ccccc1C(=O)Oc2cccc(OC(=O)c3ccccc3F)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A23 mock treatment 496572.0 -238000.0 -0.51 453764.0 -307000.0 -0.7 -0.8504 -0.9875 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 A24 mock treatment 499618.0 -235000.0 -0.5 410395.0 -350000.0 -0.8 -0.9156 -0.9747 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B01 compound treatment 417931.0 -317000.0 -0.67 450283.0 -310000.0 -0.71 -0.9739 -0.9997 3117572 ChemDiv3_000023 COc1ccc(/C=N/c2ccc(OCC(O)CN3C(C)CCCC3C)cc2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B02 compound treatment 822940.0 87900.0 0.19 470640.0 -290000.0 -0.66 -0.3341 -0.4879 1476169 ChemDiv3_000024 CC(C)(C)NC(=O)C1(CC2CC3C1)CC(C2)CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B03 compound treatment 937219.0 202000.0 0.43 672273.0 -88100.0 -0.2 0.1614 0.3411 1164812 ChemDiv3_000025 O(c1ccccc1)c2cccc(Oc3ccccc3)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B04 compound treatment 982181.0 247000.0 0.52 934901.0 174000.0 0.4 0.651 0.9906 3019828 ChemDiv3_000026 Brc1ccc(/C=N/C2CCCCC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B05 compound treatment 276947.0 -458000.0 -0.97 271313.0 -489000.0 -1.11 -1.473 -0.9977 2083946 ChemDiv3_000027 O=C(/C=C/c1ccccc1)/C=C/c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B06 compound treatment 616656.0 -118000.0 -0.25 608746.0 -152000.0 -0.34 -0.4213 -0.9878 3117574 ChemDiv3_000028 CC1(CC2(C)CC3(C)C1)CC(C/N=C/c4ccc(O)cc4)(C2)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B07 compound treatment 752896.0 17900.0 0.04 818110.0 57700.0 0.13 0.1196 0.8756 1666537 ChemDiv3_000029 COC(=O)NCC1(CC2CC3CC(C2)C1)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B08 compound treatment 1109098.0 374000.0 0.79 891095.0 131000.0 0.3 0.7708 0.9102 1021487 ChemDiv3_000030 C1CN(CCN1c2ccccn2)c3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B09 compound treatment 903494.0 168000.0 0.36 871622.0 111000.0 0.25 0.4313 0.9857 3019829 ChemDiv3_000031 COc1ccc(/C=N/c2ccc(C)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B10 compound treatment 880749.0 146000.0 0.31 963927.0 204000.0 0.46 0.5456 0.9807 1699181 ChemDiv3_000032 Cc1c(NC(=O)c2ccccc2)c(=O)n(c3ccccc3)n1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B11 compound treatment 786319.0 51300.0 0.11 713468.0 -47000.0 -0.11 0.0014 0.0094 3019830 ChemDiv3_000033 CC(C)Cc1ccc(cc1)C(C)C(=O)NC(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B12 compound treatment 1030346.0 295000.0 0.63 1057460.0 297000.0 0.68 0.9202 0.9993 3117575 ChemDiv3_000034 COc1ccc(/C=C/2\CC/C(=C\c3ccc(C)cc3)/C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B13 compound treatment 842545.0 108000.0 0.23 838964.0 78500.0 0.18 0.2875 0.9927 1119180 ChemDiv3_000035 CNC(=O)c1ccc(Oc2ccc(cc2)C(=O)NC)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B14 compound treatment 822267.0 87300.0 0.18 902932.0 143000.0 0.32 0.3599 0.9647 1616129 ChemDiv3_000036 CC(=O)Nc1cccc(Oc2ccc3C(=O)N(C(=O)c3c2)c4ccc(Oc5ccc(C)c(C)c5)cc4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B15 compound treatment 931788.0 197000.0 0.42 954127.0 194000.0 0.44 0.6064 0.9996 1336672 ChemDiv3_000037 O=C(Nc1cc(=O)c2ccccc2o1)OCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B16 compound treatment 166990.0 -568000.0 -1.2 167989.0 -592000.0 -1.35 -1.8039 -0.9984 3117576 ChemDiv3_000038 CC[n+]1ccc(C)c2cc(ccc12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B17 compound treatment 563737.0 -171000.0 -0.36 635220.0 -125000.0 -0.28 -0.458 -0.9927 3019831 ChemDiv3_000039 NNC(=S)NC1(CC2CC3CC(C2)C1)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B18 compound treatment 894022.0 159000.0 0.34 873014.0 113000.0 0.26 0.4194 0.9908 1270265 ChemDiv3_000040 Clc1ccc(cc1)S(=O)(=O)n2cnc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B19 compound treatment 1058643.0 324000.0 0.69 1015519.0 255000.0 0.58 0.8952 0.9965 3117577 ChemDiv3_000041 Cc1cc(nc2ccc3ccccc3c12)c4ccc5ccccc5n4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B20 compound treatment 1012418.0 277000.0 0.59 947181.0 187000.0 0.42 0.7161 0.9872 1591919 ChemDiv3_000042 CNc1ccc(cc1)S(=O)(=O)c2ccc(NC)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B21 compound treatment 94858.0 -640000.0 -1.36 134967.0 -625000.0 -1.42 -1.9651 -0.9997 3117578 ChemDiv3_000043 O=C(C1=C(C(=O)c2ccccc2C1=O)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B22 compound treatment 935177.0 200000.0 0.42 845047.0 84600.0 0.19 0.4361 0.936 1583295 ChemDiv3_000044 Brc1ccc(OC(=O)c2cccnc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B23 mock treatment 881561.0 147000.0 0.31 747401.0 -13000.0 -0.03 0.1988 0.6369 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 B24 mock treatment 496240.0 -239000.0 -0.51 488102.0 -272000.0 -0.62 -0.7957 -0.995 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C01 compound treatment 494468.0 -241000.0 -0.51 481652.0 -279000.0 -0.63 -0.8087 -0.9942 3019835 ChemDiv3_000045 Cc1ccn(CN2CCN(Cn3ccc(C)n3)C2=S)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C02 compound treatment 544664.0 -190000.0 -0.4 634059.0 -126000.0 -0.29 -0.4885 -0.9861 1183514 ChemDiv3_000046 CC(=O)Oc1ccc(C(=O)c2ccccc2)c(OC(=O)C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C03 compound treatment 980714.0 246000.0 0.52 981653.0 221000.0 0.5 0.724 0.9998 1699403 ChemDiv3_000047 O=C(NC1(CCC(=O)O1)C(=O)OCc2ccccc2)OCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C04 compound treatment 1074958.0 340000.0 0.72 1035324.0 275000.0 0.63 0.9515 0.9975 3019836 ChemDiv3_000048 COc1ccc(NC(=S)C)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C05 compound treatment 1176889.0 442000.0 0.94 1007384.0 247000.0 0.56 1.0594 0.97 3019837 ChemDiv3_000049 Clc1ccc(OC(=O)c2ccc(Br)cc2)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C06 compound treatment 1138164.0 403000.0 0.85 1078603.0 318000.0 0.72 1.1159 0.9966 3117579 ChemDiv3_000050 CC(C)N(C(C)C)C(=O)C[n+]1ccc(/C=N/O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C07 compound treatment 1190173.0 455000.0 0.96 1028825.0 268000.0 0.61 1.1138 0.9756 1112119 ChemDiv3_000051 CC(=O)Oc1ccc(cc1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C08 compound treatment 356982.0 -378000.0 -0.8 337129.0 -423000.0 -0.96 -1.2472 -0.9959 1921020 ChemDiv3_000052 CC[n+]1cccc(c1)c2nc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C09 compound treatment 127422.0 -608000.0 -1.29 171792.0 -589000.0 -1.34 -1.8571 -0.9998 1233273 ChemDiv3_000053 CCN1CCN(CC1)c2ccc(Nc3ccnc4cc5ccccc5cc34)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C10 compound treatment 1025063.0 290000.0 0.61 1198675.0 438000.0 1.0 1.1394 0.9731 3019838 ChemDiv3_000054 NC(=O)N1CCc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C11 compound treatment 962474.0 227000.0 0.48 992189.0 232000.0 0.53 0.7136 0.999 1021994 ChemDiv3_000055 Oc1ccc(cc1)C2(CCCCC2)c3ccc(O)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C12 compound treatment 897690.0 163000.0 0.34 1263530.0 503000.0 1.14 1.0527 0.8811 3019839 ChemDiv3_000056 CC(C)(C)OC(=O)C[n+]1cccc(c1)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C13 compound treatment 919510.0 184000.0 0.39 1066727.0 306000.0 0.7 0.769 0.9628 3117584 ChemDiv3_000057 O=C1CN(C(=O)N1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C14 compound treatment 1085359.0 350000.0 0.74 1202086.0 442000.0 1.0 1.2352 0.989 3019840 ChemDiv3_000058 O/N=C/c1cc[n+](CC(=O)N2CCCCC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C15 compound treatment 1070771.0 336000.0 0.71 1081653.0 321000.0 0.73 1.0197 0.9999 1320550 ChemDiv3_000059 COC(=O)CCS(=O)(=O)c1cccc2c(cccc12)S(=O)(=O)CCC(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C16 compound treatment 1180586.0 446000.0 0.94 1008204.0 248000.0 0.56 1.0663 0.9695 1778026 ChemDiv3_000060 OCc1c(CO)[n+]([O-])c2ccccc2[n+]1[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C17 compound treatment 839637.0 105000.0 0.22 947698.0 187000.0 0.43 0.4579 0.9538 3019841 ChemDiv3_000061 Cc1ccc(cc1)C(=O)C2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C18 compound treatment 1189282.0 454000.0 0.96 1093663.0 333000.0 0.76 1.2167 0.993 1353751 ChemDiv3_000062 Clc1cccc(NCn2c(=O)oc3ccccc23)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C19 compound treatment 1151150.0 416000.0 0.88 1231880.0 471000.0 1.07 1.3817 0.9953 1912422 ChemDiv3_000063 CCc1ccc(/N=C/c2c[nH]c3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C20 compound treatment 750303.0 15300.0 0.03 830660.0 70200.0 0.16 0.1358 0.8336 1318161 ChemDiv3_000064 C(N1CCOCCN(Cc2ccccc2)CCOCC1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C21 compound treatment 2083242.0 1350000.0 2.86 2414915.0 1650000.0 3.76 4.6809 0.9908 1038768 ChemDiv3_000065 CCN(CC)c1ccc2c(C)cc(=O)oc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C22 compound treatment 885119.0 150000.0 0.32 1035273.0 275000.0 0.62 0.6669 0.951 3019842 ChemDiv3_000066 O=C(Oc1ccc(cc1)c2ccccc2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C23 mock treatment 902648.0 168000.0 0.36 929504.0 169000.0 0.38 0.5231 0.9992 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 C24 mock treatment 443439.0 -292000.0 -0.62 556667.0 -204000.0 -0.46 -0.7646 -0.9899 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D01 compound treatment 464236.0 -271000.0 -0.57 503621.0 -257000.0 -0.58 -0.8187 -1.0 3117585 ChemDiv3_000067 C(Sc1nnnn1c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D02 compound treatment 499619.0 -235000.0 -0.5 569646.0 -191000.0 -0.43 -0.6596 -0.9976 3117586 ChemDiv3_000068 CC(C)(C)C(/C=C/c1ccc(Cl)cc1Cl)n2nnnc2C(C)(C)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D03 compound treatment 782961.0 47900.0 0.1 834310.0 73900.0 0.17 0.1907 0.971 1053376 ChemDiv3_000069 OC(=O)C1C(C(C1c2ccccc2)C(=O)O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D04 compound treatment 848463.0 113000.0 0.24 920194.0 160000.0 0.36 0.4269 0.98 3117587 ChemDiv3_000070 O=C(/C=C/N1C(=O)c2ccccc2C1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D05 compound treatment 706453.0 -28600.0 -0.06 764392.0 3970.0 0.01 -0.0364 -0.5951 3019843 ChemDiv3_000071 c1cncc(c1)c2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D06 compound treatment 914589.0 180000.0 0.38 1006769.0 246000.0 0.56 0.6652 0.9823 1343691 ChemDiv3_000072 CCN(C)CC1(CC2CC3CC(C2)C1)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D07 compound treatment 810530.0 75500.0 0.16 859456.0 99000.0 0.23 0.2724 0.986 1187732 ChemDiv3_000073 COC(=O)NC1(CC2CC3CC(C2)C1)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D08 compound treatment 840548.0 106000.0 0.22 921210.0 161000.0 0.37 0.4167 0.9722 1355186 ChemDiv3_000074 Nc1ccc(Sc2ccc3ccccc3c2Cl)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D09 compound treatment 985012.0 250000.0 0.53 887536.0 127000.0 0.29 0.5791 0.9593 1016949 ChemDiv3_000075 NC(=N)NC(=N)NCc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D10 compound treatment 934298.0 199000.0 0.42 973143.0 213000.0 0.48 0.6407 0.9977 1392304 ChemDiv3_000076 Clc1ccc(cc1)c2nnc(o2)C3CCC(CC3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D11 compound treatment 918831.0 184000.0 0.39 919854.0 159000.0 0.36 0.5319 0.9993 1388409 ChemDiv3_000077 S=c1sc2ccccc2n1CN3CCN(Cc4ccccc4)CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D12 compound treatment 994927.0 260000.0 0.55 1102978.0 343000.0 0.78 0.9403 0.9856 3117588 ChemDiv3_000078 COc1ccc(/C=C/2\CC/C(=C\c3ccc(Cl)cc3)/C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D13 compound treatment 377759.0 -357000.0 -0.76 331555.0 -429000.0 -0.98 -1.225 -0.9922 1025986 ChemDiv3_000079 Cc1ccccc1NC(=O)c2cc3ccccc3cc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D14 compound treatment 970843.0 236000.0 0.5 1033056.0 273000.0 0.62 0.7918 0.9943 1513086 ChemDiv3_000080 O=C(COc1ccc2ccccc2c1)NS(=O)(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D15 compound treatment 957018.0 222000.0 0.47 1034616.0 274000.0 0.62 0.7736 0.9904 1550944 ChemDiv3_000081 O=C(N1CC(CC1=O)c2ccccc2)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D16 compound treatment 877739.0 143000.0 0.3 1014960.0 255000.0 0.58 0.6232 0.9543 1432699 ChemDiv3_000082 CCOC(=O)c1cccc(n1)C(=O)Nc2nc3ccc(OC)cc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D17 compound treatment 1008701.0 274000.0 0.58 1001775.0 241000.0 0.55 0.7983 0.9996 1601789 ChemDiv3_000083 Cc1ccc(NC(=O)CC2(CC3CC4CC(C3)C2)C4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D18 compound treatment 907088.0 172000.0 0.36 1176566.0 416000.0 0.95 0.927 0.9141 3019844 ChemDiv3_000084 CC(C)OC(=O)n1c(=S)oc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D19 compound treatment 1009476.0 274000.0 0.58 1183280.0 423000.0 0.96 1.0912 0.9711 1581559 ChemDiv3_000085 O=C(Oc1ccc(OC(=O)c2ccccc2)cc1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D20 compound treatment 738558.0 3550.0 0.01 885748.0 125000.0 0.28 0.2068 0.7255 3117589 ChemDiv3_000086 O=S(=O)(/C=C/c1ccccc1)N2C=Cc3ccccc3C2c4c[nH]c5ccccc45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D21 compound treatment 757118.0 22100.0 0.05 952354.0 192000.0 0.44 0.3417 0.7786 1529969 ChemDiv3_000087 Nc1nnc(s1)C(=O)c2ccccc2N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D22 compound treatment 801278.0 66300.0 0.14 970952.0 211000.0 0.48 0.4378 0.8776 1119404 ChemDiv3_000088 CCCC1CCC(CC1)c2ccc(OC(=O)c3cccnc3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D23 mock treatment 868001.0 133000.0 0.28 841204.0 80800.0 0.18 0.3292 0.9784 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 D24 mock treatment 536503.0 -199000.0 -0.42 577514.0 -183000.0 -0.42 -0.5916 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E01 compound treatment 496368.0 -239000.0 -0.51 631901.0 -129000.0 -0.29 -0.5643 -0.966 3019845 ChemDiv3_000089 C1OC(OCC2OC(OC12)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E02 compound treatment 111646.0 -623000.0 -1.32 120912.0 -640000.0 -1.45 -1.9625 -0.9989 1616713 ChemDiv3_000090 CCCOc1ccc(N)cc1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E03 compound treatment 934828.0 200000.0 0.42 958407.0 198000.0 0.45 0.6178 0.9995 3117590 ChemDiv3_000091 COc1ccc(cc1OC)C(=O)CN2Cc3ccccc3C2=N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E04 compound treatment 951558.0 217000.0 0.46 936135.0 176000.0 0.4 0.6071 0.9976 3019846 ChemDiv3_000092 COc1ccc(NC(=O)C)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E05 compound treatment 1093658.0 359000.0 0.76 1113640.0 353000.0 0.8 1.1055 0.9996 3019847 ChemDiv3_000093 Nc1nc(cc[n+]1[O-])c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E06 compound treatment 467288.0 -268000.0 -0.57 460448.0 -300000.0 -0.68 -0.8836 -0.9958 3117591 ChemDiv3_000094 O/N=C/c1cc[n+](CC(=O)NC2CCCCC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E07 compound treatment 1032721.0 298000.0 0.63 1063627.0 303000.0 0.69 0.9337 0.999 1701731 ChemDiv3_000095 CCc1ccc(cc1)C(=O)Oc2ccc(C#N)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E08 compound treatment 949383.0 214000.0 0.45 994771.0 234000.0 0.53 0.6981 0.9969 1069596 ChemDiv3_000096 COC(=O)N1C(C=Cc2ccccc12)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E09 compound treatment 982401.0 247000.0 0.52 1046505.0 286000.0 0.65 0.8308 0.9943 3019848 ChemDiv3_000097 N/N=C/c1ccc(cc1)S(=O)(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E10 compound treatment 1240654.0 506000.0 1.07 1237035.0 477000.0 1.08 1.5242 1.0 3117592 ChemDiv3_000098 CN1CCN(CC1)C(=O)/C=C(/C)\C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E11 compound treatment 1091109.0 356000.0 0.75 1190088.0 430000.0 0.98 1.2246 0.9919 1026004 ChemDiv3_000099 COc1ccc2ccccc2c1c3c(OC)ccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E12 compound treatment 1136563.0 402000.0 0.85 1410695.0 650000.0 1.48 1.6473 0.9656 3019849 ChemDiv3_000100 CC(C)(C)C(=O)C[n+]1cccc(c1)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E13 compound treatment 1298990.0 564000.0 1.2 1195312.0 435000.0 0.99 1.5446 0.9955 1049039 ChemDiv3_000101 CC(=O)N(Nc1ccccc1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E14 compound treatment 261202.0 -474000.0 -1.0 294054.0 -466000.0 -1.06 -1.46 -0.9996 3117593 ChemDiv3_000102 O/N=C/c1ccc[n+](CC(=O)NC2(CC3CC4CC(C3)C2)C4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E15 compound treatment 1278920.0 544000.0 1.15 1141246.0 381000.0 0.87 1.4276 0.99 3019850 ChemDiv3_000103 CSc1ccc(cc1)c2ccc(SC)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E16 compound treatment 1051119.0 316000.0 0.67 1049862.0 289000.0 0.66 0.9392 1.0 3019851 ChemDiv3_000104 Nc1ccc(cc1)S(=O)(=O)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E17 compound treatment 992066.0 257000.0 0.54 1127003.0 367000.0 0.83 0.9747 0.9788 1913805 ChemDiv3_000105 CC(C)(C)OC(=O)Nc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E18 compound treatment 1133489.0 398000.0 0.84 1155562.0 395000.0 0.9 1.2326 0.9995 1334112 ChemDiv3_000106 Cc1ccc(NCn2c(=O)oc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E19 compound treatment 1090001.0 355000.0 0.75 1245887.0 485000.0 1.1 1.3126 0.9826 1464160 ChemDiv3_000107 OCCNC(=O)c1cc2ccccc2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E20 compound treatment 1174105.0 439000.0 0.93 1188850.0 428000.0 0.97 1.347 0.9997 1484925 ChemDiv3_000108 CC(NS(=O)(=O)c1ccc(C)cc1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E21 compound treatment 441595.0 -293000.0 -0.62 570547.0 -190000.0 -0.43 -0.7451 -0.9841 3117594 ChemDiv3_000109 [O-][S+]1NN([S+]([O-])NN1c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E22 compound treatment 316402.0 -419000.0 -0.89 364363.0 -396000.0 -0.9 -1.2642 -1.0 1033254 ChemDiv3_000110 COc1cc(NCCCC(C)N)c2ncccc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E23 mock treatment 916268.0 181000.0 0.38 796019.0 35600.0 0.08 0.3289 0.8377 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 E24 mock treatment 678837.0 -56200.0 -0.12 646629.0 -114000.0 -0.26 -0.2671 -0.938 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F01 compound treatment 484740.0 -250000.0 -0.53 681669.0 -78800.0 -0.18 -0.5018 -0.8961 1915982 ChemDiv3_000111 O=C1NC(=O)/C(=C/c2ccccc2)/C(=O)N1Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F02 compound treatment 711418.0 -23600.0 -0.05 789198.0 28800.0 0.07 0.0109 0.1323 1272580 ChemDiv3_000112 CC(=C)CN1c2ccccc2Sc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F03 compound treatment 902877.0 168000.0 0.36 926236.0 166000.0 0.38 0.5182 0.9996 1220799 ChemDiv3_000113 Cc1ccc(Nc2ccc3noc4-c5ccccc5C(=O)c2c43)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F04 compound treatment 629868.0 -105000.0 -0.22 677059.0 -83400.0 -0.19 -0.2916 -0.9967 1191611 ChemDiv3_000114 O=c1oc2ccccc2c(Nc3ccccc3)c1CN4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F05 compound treatment 837079.0 102000.0 0.22 846848.0 86400.0 0.2 0.2919 0.9988 1052238 ChemDiv3_000115 COc1ccc(C=C2C(=O)NC(=O)NC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F06 compound treatment 1056991.0 322000.0 0.68 1040436.0 280000.0 0.64 0.9328 0.9994 1363766 ChemDiv3_000116 Cc1cccc(c1)N(CC(=O)O)CC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F07 compound treatment 802409.0 67400.0 0.14 802962.0 42500.0 0.1 0.1694 0.9819 1561715 ChemDiv3_000117 O=C(Nc1ccc(cc1)C2(CC3CC4CC(C3)C2)C4)c5cccs5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F08 compound treatment 1219411.0 484000.0 1.03 873766.0 113000.0 0.26 0.9084 0.858 1160251 ChemDiv3_000118 CCCC1CCC(CC1)c2ccc(OC(=O)c3ccco3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F09 compound treatment 955197.0 220000.0 0.47 862679.0 102000.0 0.23 0.4945 0.9482 1185575 ChemDiv3_000119 Cc1cc(F)ccc1S(=O)(=O)NCC2CC3CCC2C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F10 compound treatment 1145183.0 410000.0 0.87 1078788.0 318000.0 0.72 1.1267 0.9958 1298807 ChemDiv3_000120 OCC(O)C1OC(Nc2ccc(Cl)cc2)C(O)C1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F11 compound treatment 1135801.0 401000.0 0.85 1065186.0 305000.0 0.69 1.0908 0.9949 1454827 ChemDiv3_000121 CC(C)(c1ccccc1)c2cc(CN3CCOCC3)c(O)c(CN4CCOCC4)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F12 compound treatment 1381244.0 646000.0 1.37 1543617.0 783000.0 1.78 2.2278 0.9916 1403981 ChemDiv3_000122 COc1ccc2oc(=O)c(cc2c1)c3cnc(C)s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F13 compound treatment 1561915.0 827000.0 1.75 1010615.0 250000.0 0.57 1.6418 0.8908 3117595 ChemDiv3_000123 O/N=C(\C(=O)c1ccccc1Cl)/n2cncn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F14 compound treatment 1589909.0 855000.0 1.81 1056123.0 296000.0 0.67 1.7569 0.9089 3117598 ChemDiv3_000124 CC1(C)COP(=S)(OC1)C(Nc2ccc(Cl)cc2)c3ccc(O)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F15 compound treatment 1017553.0 283000.0 0.6 1042462.0 282000.0 0.64 0.877 0.9994 1605115 ChemDiv3_000125 Oc1ccccc1c2nsnc2C(=O)N3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F16 compound treatment 939442.0 204000.0 0.43 1014437.0 254000.0 0.58 0.7148 0.99 1419832 ChemDiv3_000126 O=C(Oc1ccc(cc1)S(=O)(=O)c2ccc(OC(=O)c3cccs3)cc2)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F17 compound treatment 844910.0 110000.0 0.23 1053658.0 293000.0 0.67 0.6362 0.9008 1721700 ChemDiv3_000127 COc1cccc(c1)C2(CCCC2)c3ccc(O)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F18 compound treatment 1093845.0 359000.0 0.76 1034427.0 274000.0 0.62 0.9784 0.9951 1321397 ChemDiv3_000128 Nc1ncn(CC(O)CO)c2nc(Br)nc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F19 compound treatment 996760.0 262000.0 0.55 1102955.0 343000.0 0.78 0.943 0.9862 3019915 ChemDiv3_000129 COc1ccc(cc1)C(=O)C[n+]2ccc3n(C)nnc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F20 compound treatment 995693.0 261000.0 0.55 1077105.0 317000.0 0.72 0.8999 0.9915 1406847 ChemDiv3_000130 CCCC1CCC(CC1)c2ccc(OC(=O)c3cccs3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F21 compound treatment 1007479.0 272000.0 0.58 1055783.0 295000.0 0.67 0.8833 0.9972 1504493 ChemDiv3_000131 CC(=O)N1C(NC(=S)N)C(=O)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F22 compound treatment 935958.0 201000.0 0.43 1076799.0 316000.0 0.72 0.8098 0.9687 1667131 ChemDiv3_000132 CCOc1ccc(OC(=O)c2cccnc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F23 mock treatment 777981.0 43000.0 0.09 832580.0 72200.0 0.16 0.1804 0.9615 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 F24 mock treatment 625223.0 -110000.0 -0.23 656402.0 -104000.0 -0.24 -0.3318 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G01 compound treatment 762190.0 27200.0 0.06 652647.0 -108000.0 -0.25 -0.1325 -0.5265 1210291 ChemDiv3_000133 CN(C)CCOC(=O)c1ccc2[nH]c3CCSCc3c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G02 compound treatment 832517.0 97500.0 0.21 794539.0 34100.0 0.08 0.201 0.9105 1432983 ChemDiv3_000134 O=C(CC1(CC2CC3CC(C2)C1)C3)N4CCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G03 compound treatment 932626.0 198000.0 0.42 809758.0 49300.0 0.11 0.3755 0.8659 3019916 ChemDiv3_000135 CC(Cc1ccccc1)[n+]2cc(N)on2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G04 compound treatment 1033235.0 298000.0 0.63 975954.0 216000.0 0.49 0.7935 0.9921 1091968 ChemDiv3_000136 Nc1ccc(Br)cc1C(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G05 compound treatment 546123.0 -189000.0 -0.4 677327.0 -83100.0 -0.19 -0.4167 -0.9412 1446265 ChemDiv3_000137 CC(=O)Oc1ccc2ccc3ccc(OC(=O)C)c4ccc1c2c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G06 compound treatment 801363.0 66400.0 0.14 786523.0 26100.0 0.06 0.1414 0.9264 3019918 ChemDiv3_000138 O/N=C/c1ccc[n+](CC(=O)NCc2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G07 compound treatment 1085019.0 350000.0 0.74 908836.0 148000.0 0.34 0.7633 0.9364 3117599 ChemDiv3_000139 CC1CCC/C(=C/c2ccc(Cl)cc2)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G08 compound treatment 1104784.0 370000.0 0.78 1069621.0 309000.0 0.7 1.0514 0.9985 1662647 ChemDiv3_000140 CCOC(=O)NC(=S)Nc1ccc(NC(=O)c2cc(Cl)ccc2O)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G09 compound treatment 1394946.0 660000.0 1.4 1069978.0 310000.0 0.7 1.4869 0.9495 1320817 ChemDiv3_000141 CCN(CC)C(=O)N1CCN(CCC#N)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G10 compound treatment 1178116.0 443000.0 0.94 1214073.0 454000.0 1.03 1.3935 0.9989 1913999 ChemDiv3_000142 CC(Cc1c[nH]c2ccccc12)NC(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G11 compound treatment 1166275.0 431000.0 0.91 1105225.0 345000.0 0.78 1.2008 0.9971 3117600 ChemDiv3_000143 S=c1nc(oc2CCCCc21)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G12 compound treatment 1380608.0 646000.0 1.37 1337352.0 577000.0 1.31 1.8953 0.9998 3019921 ChemDiv3_000144 CC(C)(C)C(=O)C[n+]1ccc(cc1)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G13 compound treatment 1072023.0 337000.0 0.71 1285347.0 525000.0 1.19 1.3491 0.9699 1032623 ChemDiv3_000145 O=C(N(Nc1ccccc1)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G14 compound treatment 1.0 -735000.0 -1.56 1210737.0 450000.0 1.02 -0.3779 -0.2027 3117601 ChemDiv3_000146 OC(=O)c1ccc(NC(=O)C[n+]2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G15 compound treatment 1414555.0 680000.0 1.44 1321405.0 561000.0 1.28 1.9205 0.9982 3117602 ChemDiv3_000147 CSc1ccc(Sc2ccc(SC)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G16 compound treatment 1318976.0 584000.0 1.24 1077189.0 317000.0 0.72 1.3846 0.9668 1075919 ChemDiv3_000148 Clc1ccc(OCC(=O)NCCc2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G17 compound treatment 1167381.0 432000.0 0.92 1015412.0 255000.0 0.58 1.0581 0.9756 1146554 ChemDiv3_000149 OCC1(C(=O)c2ccccc2C1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G18 compound treatment 1450951.0 716000.0 1.52 1022071.0 262000.0 0.59 1.4939 0.9164 1723737 ChemDiv3_000150 NC(=S)c1cc2ccccc2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G19 compound treatment 1369485.0 634000.0 1.35 900851.0 140000.0 0.32 1.1769 0.8513 1601550 ChemDiv3_000151 COc1ccc(C2C(=O)c3ccccc3C2=O)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G20 compound treatment 1213765.0 479000.0 1.01 1029653.0 269000.0 0.61 1.1505 0.9707 1302822 ChemDiv3_000152 Cc1ccc(cc1)S(=O)(=O)N2CCCC2C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G21 compound treatment 1009230.0 274000.0 0.58 759004.0 -1420.0 0.0 0.4088 0.7032 3019795 ChemDiv3_000153 S=C1NN=C(C(N1)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G22 compound treatment 1228197.0 493000.0 1.05 965379.0 205000.0 0.47 1.0688 0.9337 1416806 ChemDiv3_000154 Nc1ccc(cc1)C(=O)Nc2ccc(cc2N)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G23 mock treatment 974742.0 240000.0 0.51 848360.0 87900.0 0.2 0.5007 0.9169 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 G24 mock treatment 794032.0 59000.0 0.13 651639.0 -109000.0 -0.25 -0.0864 -0.3118 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H01 compound treatment 592142.0 -143000.0 -0.3 679533.0 -80900.0 -0.18 -0.3442 -0.9714 1123126 ChemDiv3_000155 C(CN1CCOCC1)Sc2nc3ccccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H02 compound treatment 521660.0 -213000.0 -0.45 630155.0 -130000.0 -0.3 -0.5292 -0.9789 3019817 ChemDiv3_000156 CCOC(=O)c1c(C)c(C)sc1/N=C/c2ccc(cc2)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H03 compound treatment 947718.0 213000.0 0.45 978367.0 218000.0 0.5 0.6692 0.9989 3117603 ChemDiv3_000157 CCOC(=O)c1c(C)c(C)sc1/N=C/c2ccccc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H04 compound treatment 753671.0 18700.0 0.04 857703.0 97300.0 0.22 0.1844 0.8205 3019818 ChemDiv3_000158 COc1ccc(cc1)N(C(=O)/C=C/c2ccc(OC)c(OC)c2)C3=CC4CCC(C3)N4C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H05 compound treatment 976576.0 242000.0 0.51 1100912.0 340000.0 0.77 0.9095 0.9799 1020750 ChemDiv3_000159 NC(=O)c1ccc[n+](CC(=O)c2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H06 compound treatment 1391938.0 657000.0 1.39 1111443.0 351000.0 0.8 1.5491 0.9651 1221336 ChemDiv3_000160 Cc1ccc(OC(=O)c2ccccc2)c(c1)n3nc4ccccc4n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H07 compound treatment 1007574.0 273000.0 0.58 1076840.0 316000.0 0.72 0.9173 0.9941 1171342 ChemDiv3_000161 COC(=O)NC(=S)Nc1ccc(Oc2ccc(Cl)cc2Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H08 compound treatment 1149962.0 415000.0 0.88 1263598.0 503000.0 1.14 1.431 0.9916 1054931 ChemDiv3_000162 O=C(Oc1ccc(cc1)c2ccccc2)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H09 compound treatment 1358652.0 624000.0 1.32 1209005.0 449000.0 1.02 1.656 0.9918 1080023 ChemDiv3_000163 O=C1C2C3CC(C=C3)C2C(=O)N1c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H10 compound treatment 1187593.0 453000.0 0.96 1347571.0 587000.0 1.33 1.6224 0.9869 1270809 ChemDiv3_000164 Cc1ccccc1C(=O)N2N=C(CC2c3nc4ccccc4[nH]3)c5ccc(Br)cc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H11 compound treatment 1489700.0 755000.0 1.6 1660029.0 900000.0 2.05 2.5776 0.9926 1111851 ChemDiv3_000165 OCc1nc2cc3ccccc3cc2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H12 compound treatment 1314928.0 580000.0 1.23 1559912.0 799000.0 1.82 2.1546 0.9819 3117604 ChemDiv3_000166 O=C1N(C(=O)c2cc(ccc12)c3ncc(o3)c4ccccc4)c5ncn[nH]5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H13 compound treatment 136172.0 -599000.0 -1.27 189465.0 -571000.0 -1.3 -1.8156 -0.9999 3019820 ChemDiv3_000167 Oc1ccccc1/C=N/n2c3ccccc3c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H14 compound treatment 1336875.0 602000.0 1.28 1744616.0 984000.0 2.24 2.4844 0.9645 3117605 ChemDiv3_000168 C/N=C(\C)/c1c(O)c2ccccc2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H15 compound treatment 133928.0 -601000.0 -1.27 181914.0 -579000.0 -1.32 -1.8311 -0.9999 1279829 ChemDiv3_000169 Oc1ccccc1C2CCCCC2c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H16 compound treatment 1304583.0 570000.0 1.21 1501909.0 741000.0 1.69 2.0459 0.9866 1311336 ChemDiv3_000170 Nc1cccc(NC(=O)c2cccc(c2)S(=O)(=O)Nc3cccc(N)c3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H17 compound treatment 197814.0 -537000.0 -1.14 135464.0 -625000.0 -1.42 -1.81 -0.994 1341633 ChemDiv3_000171 Cc1cc(C)c2ccc(NN)nc2c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H18 compound treatment 1307174.0 572000.0 1.21 1402137.0 642000.0 1.46 1.8893 0.9958 3117606 ChemDiv3_000172 CC(=O)Nc1c(C)nn(c1O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H19 compound treatment 836739.0 102000.0 0.22 1101111.0 341000.0 0.77 0.7002 0.8709 3019822 ChemDiv3_000173 COc1ccc2nc(C)cc(S)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H20 compound treatment 1109503.0 374000.0 0.79 1213826.0 453000.0 1.03 1.2903 0.9917 1016095 ChemDiv3_000174 COC(=O)c1cccc(n1)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H21 compound treatment 846886.0 112000.0 0.24 1197997.0 438000.0 0.99 0.8712 0.8518 1229822 ChemDiv3_000175 CCN(CC)S(=O)(=O)c1cccc(c1)C(=O)Nc2ccc(I)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H22 compound treatment 858940.0 124000.0 0.26 1173879.0 413000.0 0.94 0.8505 0.8713 1484239 ChemDiv3_000176 CC(C)OC(=O)c1cccc(n1)C(=O)Nc2ccc(NC(=O)C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H23 mock treatment 827869.0 92900.0 0.2 1176369.0 416000.0 0.95 0.8079 0.8364 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 H24 mock treatment 657599.0 -77400.0 -0.16 853354.0 92900.0 0.21 0.0334 0.1247 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I01 compound treatment 732972.0 -2040.0 0.0 884920.0 125000.0 0.28 0.1971 0.6962 1528297 ChemDiv3_000177 CCN(CC)C(=O)COc1ccc(C)nc1CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I02 compound treatment 1276985.0 542000.0 1.15 1366255.0 606000.0 1.38 1.7864 0.9959 1726229 ChemDiv3_000178 O=C(NC1CCCCC1)NC2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I03 compound treatment 1126683.0 392000.0 0.83 1106882.0 346000.0 0.79 1.1441 0.9997 1695838 ChemDiv3_000179 OC(=O)c1ccc2C(=O)c3ccccc3S(=O)(=O)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I04 compound treatment 432508.0 -303000.0 -0.64 470393.0 -290000.0 -0.66 -0.9197 -0.9999 1706757 ChemDiv3_000180 CCCN(CCC)C(=O)Cn1ccc(=N)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I05 compound treatment 1208186.0 473000.0 1.0 1450437.0 690000.0 1.57 1.8186 0.9767 3019863 ChemDiv3_000181 OC(=O)c1ccc(cc1)c2ccc(Br)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I06 compound treatment 334671.0 -400000.0 -0.85 379020.0 -381000.0 -0.87 -1.2133 -0.9999 3117607 ChemDiv3_000182 C[N+](C)(CCOc1ccccc1)Cc2ccccc2.OC(=O)c1cc2ccccc2c(Br)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I07 compound treatment 1408486.0 673000.0 1.43 1469437.0 709000.0 1.61 2.1494 0.9982 1103446 ChemDiv3_000183 OC(=O)C(Cc1ccccc1)NC=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I08 compound treatment 936056.0 201000.0 0.43 1174686.0 414000.0 0.94 0.9674 0.9357 3019864 ChemDiv3_000184 NC(=S)/N=C/1\CCCCC1=C2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I09 compound treatment 1565121.0 830000.0 1.76 1167205.0 407000.0 0.92 1.8983 0.9549 3117608 ChemDiv3_000185 Clc1ccc(cc1)S(=O)(=O)/N=C/2\SCCN2S(=O)(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I10 compound treatment 1630001.0 895000.0 1.9 1796074.0 1040000.0 2.35 3.0066 0.9943 3019865 ChemDiv3_000186 NC(=O)c1ccc[n+](CC(=O)N(CC=C)CC=C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I11 compound treatment 1393864.0 659000.0 1.4 1530741.0 770000.0 1.75 2.226 0.9937 1008424 ChemDiv3_000187 Nc1ccc(Sc2ccc(N)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I12 compound treatment 1448325.0 713000.0 1.51 1081963.0 322000.0 0.73 1.5862 0.9444 3117609 ChemDiv3_000188 CC(C)(C)OC(=O)C[n+]1ccc(cc1)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I13 compound treatment 1789170.0 1050000.0 2.23 1814155.0 1050000.0 2.4 3.2742 0.9994 1590292 ChemDiv3_000189 Cc1ccc(cc1)C(=O)Oc2cc(C)cc(OC(=O)c3ccc(C)cc3)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I14 compound treatment 146654.0 -588000.0 -1.25 198638.0 -562000.0 -1.28 -1.7851 -0.9999 3019866 ChemDiv3_000190 Brc1ccc2[n+](C/C=C/c3ccccc3)cccc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I15 compound treatment 1837293.0 1100000.0 2.34 1891261.0 1130000.0 2.57 3.4703 0.9989 2121292 ChemDiv3_000191 Clc1ccc(cc1Cl)S(=O)(=O)Cc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I16 compound treatment 1170665.0 436000.0 0.92 1841004.0 1080000.0 2.46 2.3902 0.9107 1483300 ChemDiv3_000192 COc1ccc(Cl)c(NCCC(=O)O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I17 compound treatment 1496221.0 761000.0 1.61 1754677.0 994000.0 2.26 2.7395 0.9864 1243544 ChemDiv3_000193 CCOc1ccc(cc1OC)C2(CC(=O)Nc3ccccc3)C(=O)c4ccccc4C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I18 compound treatment 1682438.0 947000.0 2.01 1811704.0 1050000.0 2.39 3.1103 0.9963 1632789 ChemDiv3_000194 O=C(Nc1cccc2ccccc12)c3cc4ccccc4oc3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I19 compound treatment 1525737.0 791000.0 1.68 1620507.0 860000.0 1.96 2.568 0.9971 1020326 ChemDiv3_000195 CCOC(=O)C1=C(O)c2ccccc2C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I20 compound treatment 1640407.0 905000.0 1.92 1485317.0 725000.0 1.65 2.5226 0.9971 1160580 ChemDiv3_000196 OC(=O)C(Cc1cnc[nH]1)N2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I21 compound treatment 1532356.0 797000.0 1.69 1420701.0 660000.0 1.5 2.2567 0.9982 1223725 ChemDiv3_000197 OC(=O)CC1(CC2CC3C1)CC(CC(=O)O)(C2)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I22 compound treatment 1382936.0 648000.0 1.37 1361821.0 601000.0 1.37 1.9381 1.0 3019868 ChemDiv3_000198 OC(=O)c1ccc(C(=O)O)c(c1)c2nc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I23 mock treatment 1422414.0 687000.0 1.46 1394348.0 634000.0 1.44 2.0496 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 I24 mock treatment 1091297.0 356000.0 0.76 1001680.0 241000.0 0.55 0.9219 0.9877 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J01 compound treatment 604210.0 -131000.0 -0.28 762997.0 2580.0 0.01 -0.1919 -0.692 3117610 ChemDiv3_000199 N/N=C(\C(=O)O)/c1ccccc1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J02 compound treatment 889387.0 154000.0 0.33 827649.0 67200.0 0.15 0.3395 0.9399 3019869 ChemDiv3_000200 O=C(C[n+]1ccc(C#N)cc1)c2ccc(NC(=O)c3ccccc3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J03 compound treatment 547824.0 -187000.0 -0.4 545811.0 -215000.0 -0.49 -0.6256 -0.9947 3117612 ChemDiv3_000201 O=C(/C=C/c1c[nH]c2ccccc12)N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J04 compound treatment 934007.0 199000.0 0.42 1081175.0 321000.0 0.73 0.814 0.9661 1170304 ChemDiv3_000202 OC(=O)CCNc1cc(Cl)ccc1Oc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J05 compound treatment 878699.0 144000.0 0.3 1007767.0 247000.0 0.56 0.613 0.9585 3019870 ChemDiv3_000203 O=C(C[n+]1cccc(NC(=O)c2ccccc2)c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J06 compound treatment 1241403.0 506000.0 1.07 1562143.0 802000.0 1.82 2.048 0.9681 1618034 ChemDiv3_000204 COc1ccc(cc1)N2C(=O)C3CC=CC(C)C3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J07 compound treatment 1206796.0 472000.0 1.0 1259343.0 499000.0 1.13 1.5093 0.998 3117613 ChemDiv3_000205 CCn1c(C)[n+](CC)c2cc(ccc12)S(=O)(=O)NC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J08 compound treatment 1258041.0 523000.0 1.11 1308615.0 548000.0 1.25 1.6653 0.9983 1082227 ChemDiv3_000206 C(CSc1nc2ccccc2[nH]1)Sc3nc4ccccc4[nH]3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J09 compound treatment 1407450.0 672000.0 1.43 1847823.0 1090000.0 2.47 2.7562 0.9658 3019871 ChemDiv3_000207 Cc1ccc(cc1C)C(=O)c2ccc(C)c(C)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J10 compound treatment 1444219.0 709000.0 1.5 1764797.0 1000000.0 2.28 2.6778 0.9794 1921766 ChemDiv3_000208 CC(/N=C/c1ccccc1O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J11 compound treatment 1662255.0 927000.0 1.97 1833426.0 1070000.0 2.44 3.115 0.9943 1340958 ChemDiv3_000209 CCN(CC)CCSc1nnc2c3ccccc3n(CC(=O)N)c2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J12 compound treatment 1628083.0 893000.0 1.89 2031830.0 1270000.0 2.89 3.3827 0.979 1421356 ChemDiv3_000210 O=C(Nc1nc(cs1)c2ccccc2)c3ccc(cc3)S(=O)(=O)N4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J13 compound treatment 1565005.0 830000.0 1.76 1804285.0 1040000.0 2.37 2.9223 0.9892 3019898 ChemDiv3_000211 Oc1ccccc1/C=N/c2cccc(\N=C\c3ccccc3O)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J14 compound treatment 1573520.0 839000.0 1.78 1928176.0 1170000.0 2.65 3.1343 0.981 3117614 ChemDiv3_000212 Clc1ccc2[nH]c(=O)nc(c3ccccc3)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J15 compound treatment 435887.0 -299000.0 -0.63 506648.0 -254000.0 -0.58 -0.8564 -0.9989 1122932 ChemDiv3_000213 Oc1cc(cc(c1)C2CCCCC2)C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J16 compound treatment 1701361.0 966000.0 2.05 1867656.0 1110000.0 2.52 3.2286 0.9948 3117615 ChemDiv3_000214 CC(=O)NC1=NN(C(=O)C)C(C)(CS(=O)(=O)c2ccc(C)cc2)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J17 compound treatment 1202406.0 467000.0 0.99 1295534.0 535000.0 1.22 1.5609 0.9948 1730515 ChemDiv3_000215 CNc1ccc2cccc(Oc3ccc4cccc(O)c4n3)c2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J18 compound treatment 1575997.0 841000.0 1.78 1820613.0 1060000.0 2.41 2.9651 0.989 1591676 ChemDiv3_000216 Nc1cccc(NC(=O)CCC(=O)O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J19 compound treatment 1179507.0 444000.0 0.94 1327418.0 567000.0 1.29 1.5778 0.9881 3117616 ChemDiv3_000217 CC1(C)CC(CC(C)(C)N1)/N=C/c2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J20 compound treatment 1202755.0 468000.0 0.99 1424116.0 664000.0 1.51 1.7681 0.9793 1528923 ChemDiv3_000218 CC(C)OC(=O)c1cccc(n1)C(=O)OC(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J21 compound treatment 1233962.0 499000.0 1.06 1369690.0 609000.0 1.39 1.7274 0.9911 1320476 ChemDiv3_000219 OC(=O)CC(N1C(=O)c2ccccc2C1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J22 compound treatment 211909.0 -523000.0 -1.11 224150.0 -536000.0 -1.22 -1.6463 -0.9989 1009844 ChemDiv3_000220 Nc1cc(ccc1O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J23 mock treatment 950951.0 216000.0 0.46 1181889.0 421000.0 0.96 1.0013 0.9428 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 J24 mock treatment 565400.0 -170000.0 -0.36 697059.0 -63400.0 -0.14 -0.3561 -0.9194 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K01 compound treatment 570641.0 -164000.0 -0.35 627790.0 -133000.0 -0.3 -0.4596 -0.9974 1273679 ChemDiv3_000221 CCN(CC)CCOc1ccc2nc(sc2c1)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K02 compound treatment 858269.0 123000.0 0.26 1007553.0 247000.0 0.56 0.5821 0.9393 1202625 ChemDiv3_000222 OCCC1(CC2CC3CC(C2)C1)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K03 compound treatment 1181484.0 446000.0 0.95 1136019.0 376000.0 0.85 1.2731 0.9987 1450413 ChemDiv3_000223 CS(=O)(=O)CS(=O)(=O)C1=C(C2CCN1CC2)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K04 compound treatment 420066.0 -315000.0 -0.67 456650.0 -304000.0 -0.69 -0.9605 -0.9999 1353143 ChemDiv3_000224 CC(C)N(C(C)C)C(=O)Cn1ccc(=N)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K05 compound treatment 1003550.0 269000.0 0.57 1126713.0 366000.0 0.83 0.9914 0.9828 3117617 ChemDiv3_000225 CCCCc1ccc(CC(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K06 compound treatment 229138.0 -506000.0 -1.07 271386.0 -489000.0 -1.11 -1.5445 -0.9998 3019901 ChemDiv3_000226 CC[n+]1cccc(c1)c2nc3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K07 compound treatment 968231.0 233000.0 0.49 1372123.0 612000.0 1.39 1.333 0.9031 1058991 ChemDiv3_000227 CCc1ccc(CC(=S)N2CCOCC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K08 compound treatment 832573.0 97600.0 0.21 1365507.0 605000.0 1.38 1.119 0.8044 1049850 ChemDiv3_000228 C(N1CCN(CC1)c2ccccc2)N3CCN(CC3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K09 compound treatment 1102227.0 367000.0 0.78 1216689.0 456000.0 1.04 1.284 0.99 1529951 ChemDiv3_000229 COc1ccc2N(C)C(=O)C(C)(CC#N)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K10 compound treatment 1065464.0 330000.0 0.7 1494759.0 734000.0 1.67 1.6759 0.9256 3117618 ChemDiv3_000230 NC(=O)c1cc[n+](CC(=O)N(CC=C)CC=C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K11 compound treatment 1236330.0 501000.0 1.06 1462667.0 702000.0 1.6 1.8805 0.9804 1049796 ChemDiv3_000231 C[n+]1ccc(cc1)c2cc[n+](C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K12 compound treatment 305241.0 -430000.0 -0.91 367577.0 -393000.0 -0.89 -1.2758 -1.0 3117619 ChemDiv3_000232 O/N=C/c1ccc[n+](C/C=C/c2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K13 compound treatment 1150073.0 415000.0 0.88 1491954.0 732000.0 1.66 1.7982 0.9557 1377603 ChemDiv3_000233 Cc1cccc(NC(=O)c2cccc(c2)C(=O)Nc3cccc(C)c3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K14 compound treatment 1358150.0 623000.0 1.32 1524263.0 764000.0 1.74 2.1621 0.9909 3117620 ChemDiv3_000234 NC(=O)NC(=O)C[n+]1ccc(/C=N/O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K15 compound treatment 1282165.0 547000.0 1.16 1658439.0 898000.0 2.04 2.2639 0.9641 1086380 ChemDiv3_000235 Brc1ccc(cc1)S(=O)(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K16 compound treatment 1336654.0 602000.0 1.28 1481473.0 721000.0 1.64 2.0611 0.9923 3117621 ChemDiv3_000236 OC(=O)CN(CCc1ccccc1)CC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K17 compound treatment 1241648.0 507000.0 1.07 1601554.0 841000.0 1.91 2.1117 0.9628 1677145 ChemDiv3_000237 O=C1C(C(C2C(=O)c3ccccc3C2=O)c4ccccc4)C(=O)c5ccccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K18 compound treatment 1462877.0 728000.0 1.54 1617741.0 857000.0 1.95 2.4694 0.9933 1190677 ChemDiv3_000238 CCN(CC)c1ccc2cc(C(=O)Nc3ccccc3)c(=N)oc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K19 compound treatment 1472587.0 738000.0 1.56 1578838.0 818000.0 1.86 2.4214 0.9963 3019902 ChemDiv3_000239 CCC(=O)c1ccc2cc(OC)ccc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K20 compound treatment 1257830.0 523000.0 1.11 1252136.0 492000.0 1.12 1.5742 1.0 1231229 ChemDiv3_000240 CCCCC(N1C(=O)c2ccccc2C1=O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K21 compound treatment 1125039.0 390000.0 0.83 1182386.0 422000.0 0.96 1.263 0.9973 1111942 ChemDiv3_000241 CN(C)CCC(=O)c1ccc(Br)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K22 compound treatment 1155735.0 421000.0 0.89 1078130.0 318000.0 0.72 1.1414 0.9945 3019922 ChemDiv3_000242 Cc1cc(NC(=O)c2ccc(N)cc2)c(N)cc1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K23 mock treatment 1113601.0 379000.0 0.8 959311.0 199000.0 0.45 0.8873 0.9632 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 K24 mock treatment 635967.0 -99000.0 -0.21 719183.0 -41200.0 -0.09 -0.2148 -0.934 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L01 compound treatment 501619.0 -233000.0 -0.49 606502.0 -154000.0 -0.35 -0.5973 -0.9856 3117622 ChemDiv3_000243 CC(=O)Nc1ccc(NC(=O)/C=N/O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L02 compound treatment 810398.0 75400.0 0.16 842005.0 81600.0 0.19 0.2442 0.9972 3117623 ChemDiv3_000244 O=C(C[n+]1cccc(c1)C(=O)Nc2ccccc2)c3ccc(cc3)N4C(=O)c5ccccc5C4=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L03 compound treatment 990452.0 255000.0 0.54 1023033.0 263000.0 0.6 0.8051 0.9988 3019923 ChemDiv3_000245 CC1(C)CC(CC(C)(C)N1)NC(=O)/C=C/C(=O)NC2CC(C)(C)NC(C)(C)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L04 compound treatment 112991.0 -622000.0 -1.32 132355.0 -628000.0 -1.43 -1.9421 -0.9992 1260714 ChemDiv3_000246 CC(C)(C)c1ccc(O)c(CN2CCN(CC2)c3ccccc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L05 compound treatment 923633.0 189000.0 0.4 1020928.0 261000.0 0.59 0.7016 0.9817 3019924 ChemDiv3_000247 CC(C)N1C(=O)N(C(=CC1(C)C)C)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L06 compound treatment 1084029.0 349000.0 0.74 1116271.0 356000.0 0.81 1.0953 0.999 1635573 ChemDiv3_000248 COc1ccc(cc1CN2CCOCC2)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L07 compound treatment 259462.0 -476000.0 -1.01 265837.0 -495000.0 -1.12 -1.508 -0.9985 1417227 ChemDiv3_000249 C1CN(CCO1)c2ccc(Nc3ccnc4cc5ccccc5cc34)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L08 compound treatment 1172311.0 437000.0 0.93 1170046.0 410000.0 0.93 1.3141 1.0 3019925 ChemDiv3_000250 Brc1ccc(cc1)N(CN2C(=O)c3ccccc3C2=O)C(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L09 compound treatment 1232854.0 498000.0 1.06 1267608.0 507000.0 1.15 1.5617 0.999 1196316 ChemDiv3_000251 COc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccnc3OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L10 compound treatment 1141385.0 406000.0 0.86 1325237.0 565000.0 1.28 1.5172 0.9811 1401655 ChemDiv3_000252 CCSC1=C(C#N)C(C(=C(C)N1)C(=O)Nc2ccccc2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L11 compound treatment 1429009.0 694000.0 1.47 1580085.0 820000.0 1.86 2.3581 0.9932 1010418 ChemDiv3_000253 Oc1ccc(cc1)S(=O)(=O)c2ccc(O)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L12 compound treatment 1071776.0 337000.0 0.71 1289863.0 529000.0 1.2 1.356 0.9689 1538510 ChemDiv3_000254 CCOC(=O)n1c(=O)oc2cc(Cl)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L13 compound treatment 1269047.0 534000.0 1.13 1510957.0 751000.0 1.71 2.0071 0.9801 1642025 ChemDiv3_000255 CCOC(=O)Nc1cc(=O)c2ccccc2o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L14 compound treatment 1551469.0 816000.0 1.73 1942072.0 1180000.0 2.69 3.1236 0.9774 1641183 ChemDiv3_000256 O=C(COC(=O)c1cc2ccccc2oc1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L15 compound treatment 1368243.0 633000.0 1.34 1712853.0 952000.0 2.17 2.4804 0.9736 3019926 ChemDiv3_000257 O/N=C(\c1ccccc1)/C2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L16 compound treatment 162481.0 -573000.0 -1.21 103958.0 -656000.0 -1.49 -1.9136 -0.9947 3117624 ChemDiv3_000258 CC[n+]1c(/C=C\2/CC(C)(C)CC(=C2)C)oc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L17 compound treatment 1140788.0 406000.0 0.86 1232786.0 472000.0 1.07 1.3677 0.994 1920076 ChemDiv3_000259 Cc1cc(C)c2ccc(/C=N/O)nc2c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L18 compound treatment 150310.0 -585000.0 -1.24 196409.0 -564000.0 -1.28 -1.7832 -0.9999 3117625 ChemDiv3_000260 CC[n+]1c(/C=C/2\CC(C)CC(=C2)C)sc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L19 compound treatment 1048405.0 313000.0 0.66 1368372.0 608000.0 1.38 1.4472 0.9436 1315100 ChemDiv3_000261 CSc1nc2ccccc2n1CN(C)Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L20 compound treatment 1158187.0 423000.0 0.9 1243911.0 483000.0 1.1 1.4116 0.9949 1305784 ChemDiv3_000262 COC(=O)c1cccc(n1)C(=O)Oc2ccc(OC(=O)c3cccc(n3)C(=O)OC)c(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L21 compound treatment 910143.0 175000.0 0.37 1106127.0 346000.0 0.79 0.8183 0.9414 1433025 ChemDiv3_000263 Cc1cc(cc(C)c1N)C2(CCCCC2)c3cc(C)c(N)c(C)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L22 compound treatment 1128517.0 394000.0 0.83 1330567.0 570000.0 1.3 1.5065 0.9773 1464584 ChemDiv3_000264 CN(C)c1ccc(cc1)C(O)C(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L23 mock treatment 909085.0 174000.0 0.37 1025903.0 265000.0 0.6 0.6877 0.9721 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 L24 mock treatment 568365.0 -167000.0 -0.35 701201.0 -59200.0 -0.13 -0.345 -0.9126 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M01 compound treatment 856682.0 122000.0 0.26 730700.0 -29700.0 -0.07 0.1346 0.5048 1660133 ChemDiv3_000265 CC1=CC(=O)OC1Cc2ccc3ccccc3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M02 compound treatment 884911.0 150000.0 0.32 928939.0 169000.0 0.38 0.4956 0.9957 1710588 ChemDiv3_000266 CC(=O)Nc1nc(cs1)C2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M03 compound treatment 1071044.0 336000.0 0.71 980475.0 220000.0 0.5 0.8575 0.9851 3117626 ChemDiv3_000267 C/N=C\1/S/C(=C\c2cn(CC(=O)O)c3ccccc23)/C(=O)N1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M04 compound treatment 341643.0 -393000.0 -0.83 307923.0 -452000.0 -1.03 -1.3171 -0.9946 3019928 ChemDiv3_000268 CC(C)(C)NC(=O)C[n+]1cccc(/C=N/O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M05 compound treatment 1059705.0 325000.0 0.69 1135506.0 375000.0 0.85 1.0897 0.9944 3117629 ChemDiv3_000269 CC(=O)OC1CCC(CC1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M06 compound treatment 940942.0 206000.0 0.44 964147.0 204000.0 0.46 0.6362 0.9996 3019929 ChemDiv3_000270 CC(=O)Nc1sc2CCCCc2c1SC#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M07 compound treatment 917637.0 183000.0 0.39 1027601.0 267000.0 0.61 0.7033 0.9763 3117630 ChemDiv3_000271 CCC1(CC)C(=[N+](C)c2ccccc21)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M08 compound treatment 1088611.0 354000.0 0.75 1124086.0 364000.0 0.83 1.1147 0.9988 1692026 ChemDiv3_000272 CC1(C)CC(CC(C)(C)N1)NC(=O)c2ccccc2C(=O)NC3CC(C)(C)NC(C)(C)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M09 compound treatment 195712.0 -539000.0 -1.14 137834.0 -623000.0 -1.42 -1.8093 -0.9944 3019876 ChemDiv3_000273 CC[n+]1c(C)sc(c1c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M10 compound treatment 1045257.0 310000.0 0.66 1206033.0 446000.0 1.01 1.1815 0.9781 3117631 ChemDiv3_000274 NC(=O)c1ccc[n+](CC(=O)N2CCCCC2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M11 compound treatment 1068079.0 333000.0 0.71 1071420.0 311000.0 0.71 0.9993 1.0 1141301 ChemDiv3_000275 COC(=O)Nc1ccc(cc1)S(=O)(=O)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M12 compound treatment 741327.0 6310.0 0.01 902469.0 142000.0 0.32 0.2378 0.7358 3117632 ChemDiv3_000276 O/N=C/c1cc[n+](CCC(=O)NCc2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M13 compound treatment 987488.0 252000.0 0.54 1015909.0 255000.0 0.58 0.7892 0.9992 3019878 ChemDiv3_000277 Cc1cccc(NC(=O)/C=C/c2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M14 compound treatment 1029242.0 294000.0 0.62 972617.0 212000.0 0.48 0.7822 0.9919 3117633 ChemDiv3_000278 OC(=O)c1ccccc1NC(=O)C[n+]2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M15 compound treatment 1111370.0 376000.0 0.8 1135159.0 375000.0 0.85 1.1666 0.9995 1048436 ChemDiv3_000279 O=C(Nc1ccccc1)C2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M16 compound treatment 1085216.0 350000.0 0.74 1064139.0 304000.0 0.69 1.0132 0.9993 1410422 ChemDiv3_000280 CCNc1c(N)c(=O)oc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M17 compound treatment 1064955.0 330000.0 0.7 1044872.0 284000.0 0.65 0.9519 0.9992 3019903 ChemDiv3_000281 Nc1nonc1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M18 compound treatment 1272872.0 538000.0 1.14 1315588.0 555000.0 1.26 1.6988 0.9987 3019904 ChemDiv3_000282 CC(C)C1=CCC(C)/C(=C\c2ccc(Cl)cc2)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M19 compound treatment 1215452.0 480000.0 1.02 1154503.0 394000.0 0.9 1.3537 0.998 1010017 ChemDiv3_000283 O=C1C=CC(=O)N1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M20 compound treatment 1292075.0 557000.0 1.18 1189248.0 429000.0 0.97 1.5245 0.9955 1922526 ChemDiv3_000284 Brc1ccccc1c2nc3ccccc3c4nc5ccccc5n24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M21 compound treatment 1244677.0 510000.0 1.08 1138950.0 379000.0 0.86 1.3725 0.9936 1409537 ChemDiv3_000285 Nc1ccc(cc1)C(=O)CC(=O)Nc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M22 compound treatment 1232156.0 497000.0 1.05 1215370.0 455000.0 1.03 1.4766 1.0 1104285 ChemDiv3_000286 OC(=O)c1cc2ccc3cccc4ccc(c1)c2c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M23 mock treatment 1115978.0 381000.0 0.81 906969.0 147000.0 0.33 0.8067 0.9233 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 M24 mock treatment 640991.0 -94000.0 -0.2 608566.0 -152000.0 -0.35 -0.3851 -0.9659 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N01 compound treatment 487373.0 -248000.0 -0.52 618000.0 -142000.0 -0.32 -0.6002 -0.973 3019905 ChemDiv3_000287 C/C(=C/C(=O)O)/C=C/c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N02 compound treatment 833558.0 98500.0 0.21 871672.0 111000.0 0.25 0.3266 0.9955 1113098 ChemDiv3_000288 O=C(Oc1ccccc1OC(=O)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N03 compound treatment 906405.0 171000.0 0.36 996502.0 236000.0 0.54 0.6365 0.9819 1455237 ChemDiv3_000289 S=C1NCN(CN1)C2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N04 compound treatment 171144.0 -564000.0 -1.2 197760.0 -563000.0 -1.28 -1.7498 -0.9994 1652365 ChemDiv3_000290 CC(C)c1cc(CN2CCN(CC2)c3ccccc3)c(O)c(CN4CCN(CC4)c5ccccc5)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N05 compound treatment 1037665.0 303000.0 0.64 1041808.0 281000.0 0.64 0.9061 1.0 3019907 ChemDiv3_000291 CN(C)C/C(=N/O)/C(=O)Nc1ccc(C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N06 compound treatment 1182624.0 448000.0 0.95 1158705.0 398000.0 0.91 1.3113 0.9997 1498499 ChemDiv3_000292 COc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3)cc2)nc(OC)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N07 compound treatment 1135459.0 400000.0 0.85 1180786.0 420000.0 0.96 1.2761 0.9983 1034347 ChemDiv3_000293 N#CCCn1nnc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N08 compound treatment 1064711.0 330000.0 0.7 1191874.0 431000.0 0.98 1.1879 0.9862 3117634 ChemDiv3_000294 CC(=O)N(CN1C(=O)c2ccccc2C1=O)c3ccc4ccccc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N09 compound treatment 1101107.0 366000.0 0.78 1105999.0 346000.0 0.79 1.1044 1.0 1051930 ChemDiv3_000295 C(c1ccccc1)n2ccc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N10 compound treatment 1154861.0 420000.0 0.89 1227969.0 468000.0 1.06 1.381 0.9961 1022496 ChemDiv3_000296 OC(=O)CCCc1ccc2ccc3cccc4ccc1c2c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N11 compound treatment 1224774.0 490000.0 1.04 1020295.0 260000.0 0.59 1.152 0.9643 1579194 ChemDiv3_000297 CN(C)C(=O)c1ccc(Oc2ccc(cc2)C(=O)N(C)C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N12 compound treatment 1219467.0 484000.0 1.03 1249866.0 489000.0 1.11 1.5131 0.9992 1676465 ChemDiv3_000298 Clc1ccc(cc1)C(=O)n2c(=O)oc3cc(Cl)ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N13 compound treatment 1158153.0 423000.0 0.9 989192.0 229000.0 0.52 1.0021 0.9664 1542255 ChemDiv3_000299 CCOC(=O)c1c(O)cc(C)cc1Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N14 compound treatment 1247000.0 512000.0 1.09 980567.0 220000.0 0.5 1.1214 0.9382 3117635 ChemDiv3_000300 O=C(C[n+]1ccccc1)c2cc3ccccc3oc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N15 compound treatment 1102781.0 368000.0 0.78 912265.0 152000.0 0.35 0.7954 0.9328 1382153 ChemDiv3_000301 O=C1N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N16 compound treatment 1267316.0 532000.0 1.13 1154388.0 394000.0 0.9 1.4313 0.9935 1667966 ChemDiv3_000302 O=C(Nc1ccc(cc1)c2nc3cc(NC(=O)C4CCCCC4)ccc3o2)C5CCCCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N17 compound treatment 1106043.0 371000.0 0.79 900867.0 140000.0 0.32 0.782 0.9212 3019932 ChemDiv3_000303 COC(=O)c1cc2cc(Br)ccc2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N18 compound treatment 1091906.0 357000.0 0.76 1032916.0 272000.0 0.62 0.9731 0.9951 1508788 ChemDiv3_000304 CC(=O)Nc1ccc2oc3ccccc3c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N19 compound treatment 1286368.0 551000.0 1.17 1245560.0 485000.0 1.1 1.6064 0.9996 3019933 ChemDiv3_000305 NC(=O)CSc1nc2ccccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N20 compound treatment 1201163.0 466000.0 0.99 1187641.0 427000.0 0.97 1.3856 1.0 1682374 ChemDiv3_000306 COC(=O)c1cccc(n1)C(=O)Nc2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N21 compound treatment 1217042.0 482000.0 1.02 1058882.0 298000.0 0.68 1.2024 0.9802 1467868 ChemDiv3_000307 Cc1ccc(NC(=O)C2(CC3CC4CC(C3)C2)C4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N22 compound treatment 1074401.0 339000.0 0.72 999589.0 239000.0 0.54 0.8933 0.9905 3019936 ChemDiv3_000308 O=C/1OC(=N\C1=C/c2ccco2)c3ccc(cc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N23 mock treatment 896080.0 161000.0 0.34 834694.0 74300.0 0.17 0.3609 0.9473 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 N24 mock treatment 558541.0 -176000.0 -0.37 619690.0 -141000.0 -0.32 -0.4908 -0.997 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O01 compound treatment 335027.0 -400000.0 -0.85 329645.0 -431000.0 -0.98 -1.2921 -0.9974 3117636 ChemDiv3_000309 NNc1nc(cc(n1)c2ccccc2O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O02 compound treatment 854008.0 119000.0 0.25 1280784.0 520000.0 1.18 1.0149 0.839 3019937 ChemDiv3_000310 CCCc1[nH]c(Br)nc1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O03 compound treatment 1060191.0 325000.0 0.69 1428549.0 668000.0 1.52 1.5616 0.9361 1573334 ChemDiv3_000311 COc1nsnc1N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O04 compound treatment 983219.0 248000.0 0.53 1457924.0 698000.0 1.59 1.4934 0.8938 3117637 ChemDiv3_000312 CN(C)C(=O)C[n+]1cccc(/C=N/O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O05 compound treatment 1093865.0 359000.0 0.76 1617956.0 858000.0 1.95 1.9165 0.9158 1280359 ChemDiv3_000313 CCCCC1CCC(CC1)c2ccc(cc2)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O06 compound treatment 291913.0 -443000.0 -0.94 299088.0 -461000.0 -1.05 -1.4059 -0.9985 3019939 ChemDiv3_000314 C[n+]1ccccc1c2nc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O07 compound treatment 1111806.0 377000.0 0.8 1537656.0 777000.0 1.77 1.8143 0.9356 1372721 ChemDiv3_000315 CCCCC1CCC(CC1)C(=O)Oc2ccc(OCC)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O08 compound treatment 1111655.0 377000.0 0.8 1264752.0 504000.0 1.15 1.3754 0.9844 1559693 ChemDiv3_000316 CCOC(=O)c1[nH]c2ccc(OCC)cc2c1CCCN3C(=O)c4ccccc4C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O09 compound treatment 1300799.0 566000.0 1.2 1502332.0 742000.0 1.69 2.0409 0.986 1672292 ChemDiv3_000317 COC(=O)c1ccc2n(CCO)c(C)nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O10 compound treatment 1241865.0 507000.0 1.07 1416433.0 656000.0 1.49 1.8144 0.9871 3117638 ChemDiv3_000318 CC(C)(C)CC[n+]1ccc(cc1)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O11 compound treatment 288569.0 -446000.0 -0.95 227016.0 -533000.0 -1.21 -1.5268 -0.9925 3019783 ChemDiv3_000319 CN1C(N(C)c2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O12 compound treatment 1100305.0 365000.0 0.77 1191517.0 431000.0 0.98 1.2406 0.9932 3019784 ChemDiv3_000320 CC(C)(C)CC[n+]1ccc(/C=N/O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O13 compound treatment 1352712.0 618000.0 1.31 1367198.0 607000.0 1.38 1.9014 0.9997 1564111 ChemDiv3_000321 Cc1ccc(cc1)C(=O)c2ccc(Oc3ccccc3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O14 compound treatment 1449486.0 714000.0 1.51 1552391.0 792000.0 1.8 2.3442 0.9963 1011033 ChemDiv3_000322 Cc1nc(N)c(nc1C)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O15 compound treatment 175787.0 -559000.0 -1.19 200573.0 -560000.0 -1.27 -1.7383 -0.9994 1628748 ChemDiv3_000323 CN(CC(=O)C1=C(C(=O)c2ccccc2C1=O)c3ccc(Br)cc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O16 compound treatment 1160175.0 425000.0 0.9 1420099.0 660000.0 1.5 1.6979 0.9703 1540210 ChemDiv3_000324 Nc1c(N2CCOCC2)c3ccccc3oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O17 compound treatment 1256051.0 521000.0 1.1 1417065.0 657000.0 1.49 1.8367 0.989 1072203 ChemDiv3_000325 CCCn1c2ccccc2c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O18 compound treatment 1057918.0 323000.0 0.68 1348659.0 588000.0 1.34 1.4297 0.9516 3019785 ChemDiv3_000326 COc1ccc(/C=C/2\C(C)CC=C(C(C)C)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O19 compound treatment 377953.0 -357000.0 -0.76 406778.0 -354000.0 -0.8 -1.1038 -0.9995 1084080 ChemDiv3_000327 CC[n+]1ccc(C)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O20 compound treatment 1332417.0 597000.0 1.27 1502636.0 742000.0 1.69 2.0887 0.99 1594899 ChemDiv3_000328 COC(=O)CNC(=O)c1cc(OC)c(OC)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O21 compound treatment 1310419.0 575000.0 1.22 1387375.0 627000.0 1.43 1.8705 0.997 1181132 ChemDiv3_000329 O=C(NCC1(CC2CC3CC(C2)C1)C3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O22 compound treatment 1237900.0 503000.0 1.07 1177318.0 417000.0 0.95 1.4241 0.9983 1124218 ChemDiv3_000330 CCc1nc(C)ccc1OCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O23 mock treatment 1029827.0 295000.0 0.62 1134799.0 374000.0 0.85 1.0438 0.9885 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 O24 mock treatment 474911.0 -260000.0 -0.55 532659.0 -228000.0 -0.52 -0.7561 -0.9995 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P01 compound treatment 352023.0 -383000.0 -0.81 483618.0 -277000.0 -0.63 -1.0191 -0.9921 1003174 ChemDiv3_000331 CC(O)c1ccc(Oc2ccc(cc2)C(C)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P02 compound treatment 465409.0 -270000.0 -0.57 624349.0 -136000.0 -0.31 -0.6229 -0.9584 3019787 ChemDiv3_000332 CN(C)c1ccc(/C=N/c2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P03 compound treatment 488209.0 -247000.0 -0.52 771180.0 10800.0 0.02 -0.3527 -0.6733 1340347 ChemDiv3_000333 CC(C)(C)c1cc(CN2CCN(CCC#N)CC2)cc(c1O)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P04 compound treatment 584319.0 -151000.0 -0.32 1037613.0 277000.0 0.63 0.2197 0.311 3019803 ChemDiv3_000334 COc1cccc2s/c(=N/C(=O)CC3(CC4CC5CC(C4)C3)C5)/n(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P05 compound treatment 576916.0 -158000.0 -0.34 884398.0 124000.0 0.28 -0.0377 -0.086 1922875 ChemDiv3_000335 CCN(CC)C(=O)C1(CC2CC3C1)CC(C2)CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P06 compound treatment 588680.0 -146000.0 -0.31 950756.0 190000.0 0.43 0.0866 0.1627 3117639 ChemDiv3_000336 O/N=C/c1cccc[n+]1CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P07 compound treatment 610500.0 -125000.0 -0.26 951216.0 191000.0 0.43 0.1201 0.2365 1035295 ChemDiv3_000337 CC(C)(C)N1C(=O)c2ccccc2C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P08 compound treatment 569510.0 -166000.0 -0.35 722719.0 -37700.0 -0.09 -0.3087 -0.8547 1005478 ChemDiv3_000338 Nc1ccc(Oc2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P09 compound treatment 723051.0 -12000.0 -0.03 819744.0 59300.0 0.13 0.0774 0.5643 1734538 ChemDiv3_000339 OC(=O)CCNC(=O)c1ccco1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P10 compound treatment 598233.0 -137000.0 -0.29 537468.0 -223000.0 -0.51 -0.5635 -0.9649 3117642 ChemDiv3_000340 CN(C)c1ccc(/C=C/2\CCC/C(=C\c3ccccc3)/C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P11 compound treatment 697920.0 -37100.0 -0.08 527155.0 -233000.0 -0.53 -0.4306 -0.8032 1511725 ChemDiv3_000341 COC(=O)c1ccc2C(=O)N(C(=O)c2c1)c3cccc(c3)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P12 compound treatment 636783.0 -98200.0 -0.21 502297.0 -258000.0 -0.59 -0.5622 -0.9029 1287341 ChemDiv3_000342 O=S(=O)(N1CCOCC1)c2cccc(c2)S(=O)(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P13 compound treatment 690434.0 -44600.0 -0.09 512628.0 -248000.0 -0.56 -0.4652 -0.8143 1166133 ChemDiv3_000343 CN(C)CCOC(=O)c1ccc2n(CCN(C)C)c(C)c(C)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P14 compound treatment 736149.0 1140.0 0.0 615026.0 -145000.0 -0.33 -0.232 -0.7019 1920545 ChemDiv3_000344 O=c1cc([nH]c(=S)[nH]1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P15 compound treatment 580328.0 -155000.0 -0.33 643335.0 -117000.0 -0.27 -0.4201 -0.9946 3117643 ChemDiv3_000345 Oc1ccc(Br)cc1/C=N\CC2(CC3CC4CC(C3)CC2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P16 compound treatment 924828.0 190000.0 0.4 883029.0 123000.0 0.28 0.4817 0.9839 1350693 ChemDiv3_000346 Nc1ccc(CCc2nc3ccccc3[nH]2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P17 compound treatment 935522.0 201000.0 0.43 803468.0 43000.0 0.1 0.3698 0.8477 1509469 ChemDiv3_000347 CCN(CC)C(=O)c1cc(nc2ccccc12)c3cc(C(=O)N(CC)CC)c4ccccc4n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P18 compound treatment 830823.0 95800.0 0.2 914676.0 154000.0 0.35 0.3916 0.9663 3019852 ChemDiv3_000348 O/N=C(\Cn1cncn1)/c2ccc(Cl)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P19 compound treatment 967312.0 232000.0 0.49 1087233.0 327000.0 0.74 0.8736 0.98 1127886 ChemDiv3_000349 C(Cc1nc2ccccc2o1)Cc3nc4ccccc4o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P20 compound treatment 1021076.0 286000.0 0.61 1132468.0 372000.0 0.85 1.0269 0.9867 1524725 ChemDiv3_000350 COC(=O)c1cccc(n1)C(=O)Nc2cnc3ccccc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P21 compound treatment 373726.0 -361000.0 -0.77 474479.0 -286000.0 -0.65 -1.0013 -0.9967 1740437 ChemDiv3_000351 OC(CNCc1ccccc1)C2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P22 compound treatment 503455.0 -232000.0 -0.49 786037.0 25600.0 0.06 -0.3059 -0.6189 3019853 ChemDiv3_000352 Brc1ccc(cc1)S(=O)(=O)/N=C(\Oc2ccccc2)/c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P23 mock treatment 460912.0 -274000.0 -0.58 637538.0 -123000.0 -0.28 -0.6084 -0.9437 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2001 P24 mock treatment 396351.0 -339000.0 -0.72 545975.0 -214000.0 -0.49 -0.8524 -0.9822 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A01 compound treatment 934965.0 146000.0 0.31 1156361.0 349000.0 0.79 0.7802 0.9155 1487428 ChemDiv3_000705 CCOC(=O)C1=C(CC)NC2=C(C1c3ccc(Cl)cc3)C(=O)CCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A02 compound treatment 446016.0 -343000.0 -0.73 452015.0 -355000.0 -0.81 -1.0851 -0.9986 1295860 ChemDiv3_000706 Ic1ccc(NC(=O)COc2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A03 compound treatment 564734.0 -224000.0 -0.48 418038.0 -389000.0 -0.88 -0.9618 -0.9577 1077646 ChemDiv3_000707 Clc1ccc2Sc3ccccc3N(CCC#N)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A04 compound treatment 719055.0 -70100.0 -0.15 497414.0 -310000.0 -0.7 -0.6028 -0.8378 3117740 ChemDiv3_000708 FC(F)(F)Oc1ccc(cc1)N2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A05 compound treatment 552653.0 -236000.0 -0.5 412356.0 -395000.0 -0.9 -0.989 -0.9622 3020717 ChemDiv3_000709 NC(=S)N1C(CCN1c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A06 compound treatment 728315.0 -60800.0 -0.13 486449.0 -321000.0 -0.73 -0.6066 -0.8194 1443291 ChemDiv3_000710 OCCc1ccc(s1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A07 compound treatment 522852.0 -266000.0 -0.56 472923.0 -334000.0 -0.76 -0.9363 -0.9893 3117741 ChemDiv3_000711 CCN(N(CC)S(=O)(=O)c1ccc(C)cc1)C2=NS(=O)(=O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A08 compound treatment 582698.0 -206000.0 -0.44 515136.0 -292000.0 -0.66 -0.7787 -0.9796 3020718 ChemDiv3_000712 COc1ccccc1/N=C/c2ccsc2S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A09 compound treatment 649867.0 -139000.0 -0.3 491714.0 -315000.0 -0.72 -0.7157 -0.9231 1233664 ChemDiv3_000713 O=C(CCN1C(=O)c2ccccc2C1=O)NCc3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A10 compound treatment 535903.0 -253000.0 -0.54 662071.0 -145000.0 -0.33 -0.6127 -0.9726 1914325 ChemDiv3_000714 NC(=N)SCCS(=O)(=O)c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A11 compound treatment 523346.0 -266000.0 -0.56 617759.0 -189000.0 -0.43 -0.7027 -0.9912 1506625 ChemDiv3_000715 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c3ccc(OC)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A12 compound treatment 474060.0 -315000.0 -0.67 595298.0 -212000.0 -0.48 -0.8127 -0.9871 1069326 ChemDiv3_000716 FC(F)(F)c1ccccc1NC(=O)c2ccccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A13 compound treatment 547371.0 -242000.0 -0.51 637861.0 -169000.0 -0.38 -0.6344 -0.99 1446136 ChemDiv3_000717 COc1ccc(NC(=O)C2CSC(C)(C)N2C=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A14 compound treatment 437754.0 -351000.0 -0.74 452723.0 -354000.0 -0.81 -1.0963 -0.9992 3020719 ChemDiv3_000718 COc1ccc(/C=N/c2nc3ccccc3n2Cc4ccc(Cl)cc4)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A15 compound treatment 814675.0 25600.0 0.05 699596.0 -107000.0 -0.24 -0.1344 -0.5372 1718021 ChemDiv3_000719 COC(=O)c1cc(Cl)c(NC(=S)NC(=O)C(C)(C)C)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A16 compound treatment 559884.0 -229000.0 -0.49 544619.0 -262000.0 -0.6 -0.7655 -0.9948 3117742 ChemDiv3_000720 CN(C)c1ccc(/C=N/c2nc3ccccc3n2Cc4ccc(C)cc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A17 compound treatment 595685.0 -193000.0 -0.41 510192.0 -297000.0 -0.67 -0.7672 -0.9715 1339224 ChemDiv3_000721 COC(=O)C(Cc1c[nH]c2ccccc12)NS(=O)(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A18 compound treatment 681471.0 -108000.0 -0.23 624721.0 -182000.0 -0.41 -0.4545 -0.9604 1054488 ChemDiv3_000722 Cc1cc(C)n(n1)S(=O)(=O)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A19 compound treatment 742790.0 -46300.0 -0.1 607096.0 -200000.0 -0.45 -0.3909 -0.8404 1779183 ChemDiv3_000723 CC(C)COC(=O)CNc1n[nH]c(=O)[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A20 compound treatment 518811.0 -270000.0 -0.57 500941.0 -306000.0 -0.7 -0.8973 -0.9953 3117743 ChemDiv3_000724 CCOc1cc(/C=C/2\Sc3ccccc3C2=O)cc(I)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A21 compound treatment 509306.0 -280000.0 -0.59 467550.0 -340000.0 -0.77 -0.9652 -0.9915 1646638 ChemDiv3_000725 COC(=O)C(Cc1ccc(O)cc1)NC(=O)c2ccccc2OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A22 compound treatment 481159.0 -308000.0 -0.65 423755.0 -383000.0 -0.87 -1.0778 -0.9899 1624682 ChemDiv3_000726 COC(=O)c1ccccc1NC(=O)CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A23 mock treatment 542615.0 -246000.0 -0.52 400954.0 -406000.0 -0.92 -1.0224 -0.9637 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 A24 mock treatment 502112.0 -287000.0 -0.61 393353.0 -414000.0 -0.94 -1.0953 -0.9778 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B01 compound treatment 1415577.0 626000.0 1.33 1238342.0 431000.0 0.98 1.6324 0.9889 1725673 ChemDiv3_000727 CCc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B02 compound treatment 809753.0 20600.0 0.04 908846.0 102000.0 0.23 0.1946 0.8262 3117744 ChemDiv3_000728 CN1C(=O)/C(=C\2/SC(=S)N(NC(=O)C)C2=O)/c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B03 compound treatment 1076389.0 287000.0 0.61 945090.0 138000.0 0.31 0.6525 0.9525 3020720 ChemDiv3_000729 Cc1cccc(c1)C(=O)Oc2ccc(C)c(C)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B04 compound treatment 812640.0 23500.0 0.05 856261.0 49200.0 0.11 0.1144 0.9338 1254173 ChemDiv3_000730 Cc1ccccc1OCCn2c(SCc3nc4ccccc4[nH]3)nc5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B05 compound treatment 1173133.0 384000.0 0.81 907872.0 101000.0 0.23 0.7377 0.8723 3020816 ChemDiv3_000731 C1CCC2CC(OCC2C1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B06 compound treatment 1142390.0 353000.0 0.75 1098625.0 292000.0 0.66 0.9983 0.9981 3117745 ChemDiv3_000732 Cc1ccc(cc1)S(=O)(=O)/N=C(/NC(=S)Nc2ccccc2)\c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B07 compound treatment 782000.0 -7110.0 -0.02 778032.0 -29000.0 -0.07 -0.0573 -0.8467 3020817 ChemDiv3_000733 CCN(CC)C(=O)CSc1nnc(o1)c2ccccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B08 compound treatment 1171868.0 383000.0 0.81 1015131.0 208000.0 0.47 0.9083 0.967 3117746 ChemDiv3_000734 CC(=O)NC(=O)c/1cc2c(ccc3ccccc32)o\c1=N/c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B09 compound treatment 112001.0 -677000.0 -1.44 115746.0 -691000.0 -1.57 -2.1264 -0.999 1423328 ChemDiv3_000735 OC(CNCc1ccccc1)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B10 compound treatment 1070677.0 282000.0 0.6 986990.0 180000.0 0.41 0.7113 0.983 1240251 ChemDiv3_000736 Cc1c(Cl)cccc1NC(=O)c2cccnc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B11 compound treatment 1124341.0 335000.0 0.71 900485.0 93400.0 0.21 0.6527 0.88 3020818 ChemDiv3_000737 CCOc1ccc-2c(c1)C(=O)c3cc(OCC)ccc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B12 compound treatment 858381.0 69300.0 0.15 966813.0 160000.0 0.36 0.3607 0.9206 1727003 ChemDiv3_000738 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2ccc3sc(SC)nc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B13 compound treatment 945325.0 156000.0 0.33 804883.0 -2180.0 0.0 0.2307 0.6965 1740255 ChemDiv3_000739 Cc1ccc(cc1)S(=O)(=O)N2CCN(C2c3ccccc3)C(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B14 compound treatment 715264.0 -73800.0 -0.16 786933.0 -20100.0 -0.05 -0.1431 -0.8771 3020819 ChemDiv3_000740 CC1(C)CC(=S)C=C(C1)N2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B15 compound treatment 735750.0 -53400.0 -0.11 904043.0 97000.0 0.22 0.0759 0.3064 1741101 ChemDiv3_000741 Clc1cc2sc(=O)oc2cc1OC(=O)NC3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B16 compound treatment 847460.0 58400.0 0.12 847833.0 40800.0 0.09 0.153 0.9899 3117538 ChemDiv3_000742 COc1ccc(OC)c(/N=C/c2cc(I)cc(C)c2O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B17 compound treatment 858551.0 69400.0 0.15 979595.0 173000.0 0.39 0.3815 0.9105 3117539 ChemDiv3_000743 CCOc1ccc(cc1)N2C(=O)S/C(=C/3\C(=O)Nc4ccccc34)/C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B18 compound treatment 562347.0 -227000.0 -0.48 534621.0 -272000.0 -0.62 -0.7779 -0.9921 1455599 ChemDiv3_000744 CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)Nc2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B19 compound treatment 1104778.0 316000.0 0.67 927031.0 120000.0 0.27 0.6661 0.9217 1507311 ChemDiv3_000745 CC(C)CN(CC(C)C)C(=O)c1cc2ccccc2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B20 compound treatment 1255433.0 466000.0 0.99 948373.0 141000.0 0.32 0.9262 0.891 3117540 ChemDiv3_000746 CCN1C(=O)/C(=C/Nc2ccccc2)/OC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B21 compound treatment 1033238.0 244000.0 0.52 821981.0 14900.0 0.03 0.3899 0.7518 1429235 ChemDiv3_000747 CCOc1ccc(NC(=O)CCOc2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B22 compound treatment 906261.0 117000.0 0.25 805996.0 -1070.0 0.0 0.1739 0.7002 1159158 ChemDiv3_000748 O=C1CC(CC(=C1)NCc2ccco2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B23 mock treatment 1070436.0 281000.0 0.6 891907.0 84800.0 0.19 0.5581 0.8904 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 B24 mock treatment 556247.0 -233000.0 -0.49 530205.0 -277000.0 -0.63 -0.7941 -0.9928 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C01 compound treatment 560171.0 -229000.0 -0.49 513462.0 -294000.0 -0.67 -0.8152 -0.9877 1611722 ChemDiv3_000749 CCOC(=O)C1=C(CC)NC2=C(C1c3ccccc3OCC)C(=O)CCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C02 compound treatment 562893.0 -226000.0 -0.48 590752.0 -216000.0 -0.49 -0.6868 -0.9999 1332565 ChemDiv3_000750 CCOC(=O)c1ccc(NC(=O)c2ccc(C)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C03 compound treatment 702399.0 -86700.0 -0.18 671461.0 -136000.0 -0.31 -0.348 -0.9695 1451908 ChemDiv3_000751 CCOC(=O)Nc1ccc2Sc3ccccc3N(C(=O)CCN(C)C)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C04 compound treatment 1283480.0 494000.0 1.05 1150956.0 344000.0 0.78 1.2939 0.9896 2112223 ChemDiv3_000752 O=c1oc2ccccc2cc1c3cn4c(n3)sc5ccccc54 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C05 compound treatment 1076179.0 287000.0 0.61 899229.0 92200.0 0.21 0.5785 0.8988 1471012 ChemDiv3_000753 S=C(Nc1ccccc1)N2CCCN2c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C06 compound treatment 1200201.0 411000.0 0.87 881822.0 74800.0 0.17 0.7364 0.8294 1915139 ChemDiv3_000754 NC(C(=O)O)c1ccc(CCCC(=O)O)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C07 compound treatment 874446.0 85300.0 0.18 724838.0 -82200.0 -0.19 -0.0043 -0.0164 1351042 ChemDiv3_000755 O=C(Nc1ccccc1)Nc2ccc3OCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C08 compound treatment 834903.0 45800.0 0.1 726907.0 -80200.0 -0.18 -0.0602 -0.2916 3020820 ChemDiv3_000756 CN(/C=C\1/C=C(C)SC1=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C09 compound treatment 1356456.0 567000.0 1.2 1136065.0 329000.0 0.75 1.3794 0.9739 3117541 ChemDiv3_000757 Clc1ccc(C(=O)OCCCN2C(=O)c3ccccc3C2=O)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C10 compound treatment 1142105.0 353000.0 0.75 1100951.0 294000.0 0.67 1.0016 0.9984 1673647 ChemDiv3_000758 O=C1CC(OC21CCCCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C11 compound treatment 1152314.0 363000.0 0.77 1100899.0 294000.0 0.67 1.0168 0.9975 1920609 ChemDiv3_000759 FC(F)(F)c1ccccc1NC(=O)NC2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C12 compound treatment 1396614.0 608000.0 1.29 981652.0 175000.0 0.4 1.1914 0.884 1187258 ChemDiv3_000760 O=C(N(CC#N)CC#N)c1ccc(cc1)C(=O)N(CC#N)CC#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C13 compound treatment 1603183.0 814000.0 1.73 1053801.0 247000.0 0.56 1.617 0.8911 1351252 ChemDiv3_000761 CC(C)C(=O)Oc1ccc2c(c1)oc(=O)c3ccccc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C14 compound treatment 1010437.0 221000.0 0.47 1136402.0 329000.0 0.75 0.8612 0.9747 3117542 ChemDiv3_000762 Clc1ccc(Cn2c(/N=C/c3ccc4OCOc4c3)nc5ccccc25)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C15 compound treatment 967264.0 178000.0 0.38 1183175.0 376000.0 0.86 0.8717 0.9325 1648199 ChemDiv3_000763 Nc1c(C#N)c2nc3ccccc3nc2n1c4ccc(O)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C16 compound treatment 1064941.0 276000.0 0.58 1083293.0 276000.0 0.63 0.8576 0.9994 3117543 ChemDiv3_000764 Cc1ccc(Cn2c(/N=C/c3ccc(Br)cc3)nc4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C17 compound treatment 1089662.0 301000.0 0.64 1108639.0 302000.0 0.69 0.9354 0.9993 3020844 ChemDiv3_000765 CN(Cc1ccccc1)C(=O)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C18 compound treatment 1210918.0 422000.0 0.89 1156896.0 350000.0 0.8 1.1947 0.9983 1586578 ChemDiv3_000766 Brc1ccc(cc1)C(=O)COC(=O)C2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C19 compound treatment 1432588.0 643000.0 1.36 994537.0 187000.0 0.43 1.266 0.8858 1919025 ChemDiv3_000767 FC(F)(F)c1cccc(NC(=O)COc2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C20 compound treatment 1546187.0 757000.0 1.6 1037042.0 230000.0 0.52 1.5046 0.8914 3020845 ChemDiv3_000768 NNC(=O)c1ccc(/C=N\O)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C21 compound treatment 866926.0 77800.0 0.16 706221.0 -101000.0 -0.23 -0.0455 -0.1609 3020846 ChemDiv3_000769 Brc1ccc(NC(=O)/C=C/c2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C22 compound treatment 1172266.0 383000.0 0.81 966275.0 159000.0 0.36 0.8303 0.9337 1510082 ChemDiv3_000770 OC(=O)CCC(=O)NCc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C23 mock treatment 1072072.0 283000.0 0.6 974525.0 167000.0 0.38 0.6934 0.9759 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 C24 mock treatment 627815.0 -161000.0 -0.34 621145.0 -186000.0 -0.42 -0.5407 -0.9945 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D01 compound treatment 488382.0 -301000.0 -0.64 462495.0 -345000.0 -0.78 -1.0047 -0.9948 1123230 ChemDiv3_000771 Oc1ccccc1N2C(=O)C3CC=CCC3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D02 compound treatment 634815.0 -154000.0 -0.33 581550.0 -226000.0 -0.51 -0.5938 -0.9764 1485584 ChemDiv3_000772 CCN(CC)c1ccc(NC(=O)C(C)C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D03 compound treatment 987568.0 198000.0 0.42 1067064.0 260000.0 0.59 0.7155 0.9861 3020847 ChemDiv3_000773 O=C(NN1C(=O)CSC1=S)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D04 compound treatment 1051538.0 262000.0 0.56 1144556.0 337000.0 0.77 0.936 0.9875 3117544 ChemDiv3_000774 C(CSc1nc2ccccc2[nH]1)CN3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D05 compound treatment 1103368.0 314000.0 0.67 1155046.0 348000.0 0.79 1.0305 0.9963 1778456 ChemDiv3_000775 OC(=O)CC(Sc1nc2sc3CCCCc3c2c(=O)[nH]1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D06 compound treatment 1112073.0 323000.0 0.68 1205933.0 399000.0 0.91 1.1254 0.9904 3020848 ChemDiv3_000776 FC(F)(F)c1cccc(NC(=O)c2ccc3ccccc3c2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D07 compound treatment 1193892.0 405000.0 0.86 1056972.0 250000.0 0.57 1.0086 0.98 3020849 ChemDiv3_000777 Cc1sc(Nc2ccccc2F)nc1c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D08 compound treatment 1207751.0 419000.0 0.89 959093.0 152000.0 0.35 0.872 0.9155 1364991 ChemDiv3_000778 Brc1cccc(c1)c2nnc(o2)c3cc4ccccc4oc3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D09 compound treatment 1281991.0 493000.0 1.04 1577476.0 770000.0 1.75 1.9774 0.9695 3117545 ChemDiv3_000779 CCOC(=O)c1c(/N=c/2\oc3ccc4ccccc4c3cc2C(=O)N)sc5CCCCc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D10 compound treatment 1014319.0 225000.0 0.48 1388752.0 582000.0 1.32 1.2728 0.9052 1665286 ChemDiv3_000780 CN1CCN(CC1)NC(=O)c2ccc(cc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D11 compound treatment 1177592.0 388000.0 0.82 1875376.0 1070000.0 2.43 2.2998 0.8967 1652224 ChemDiv3_000781 COC(=O)COc1ccc-2c(c1)C(=NO)c3cc(OCC(=O)OC)ccc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D12 compound treatment 1083458.0 294000.0 0.62 1050956.0 244000.0 0.55 0.8333 0.9983 1235358 ChemDiv3_000782 CCC1Nc2ccccc2-c3nnc(SC)nc3O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D13 compound treatment 1258710.0 470000.0 1.0 1053635.0 247000.0 0.56 1.1004 0.9631 1443634 ChemDiv3_000783 OC(=O)C1C2CC=CC2c3cc(Cl)cc4C5C=CCC5CN1c43 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D14 compound treatment 1126085.0 337000.0 0.71 1197914.0 391000.0 0.89 1.1335 0.9941 3020850 ChemDiv3_000784 Fc1cccc(c1)C2=N/C(=C\c3cccc4ccccc34)/C(=O)O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D15 compound treatment 1203461.0 414000.0 0.88 1139489.0 332000.0 0.76 1.1556 0.9972 1569541 ChemDiv3_000785 CCOC(=O)c1cnn(c1N(C(=O)c2ccccc2F)C(=O)c3ccccc3F)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D16 compound treatment 1043692.0 255000.0 0.54 1081724.0 275000.0 0.62 0.8232 0.9974 3020851 ChemDiv3_000786 CC(=O)Nc1cccc(/N=C/c2cc(I)cc(C)c2O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D17 compound treatment 1257828.0 469000.0 0.99 974355.0 167000.0 0.38 0.9716 0.9132 1355069 ChemDiv3_000787 CS(=O)(=O)Nc1ccc(Cl)cc1C(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D18 compound treatment 337996.0 -451000.0 -0.96 309961.0 -497000.0 -1.13 -1.4754 -0.9965 1626307 ChemDiv3_000788 CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)NCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D19 compound treatment 1269021.0 480000.0 1.02 992981.0 186000.0 0.42 1.0183 0.9243 3117546 ChemDiv3_000789 Cc1cc(C)c(C(=O)NCC=C)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D20 compound treatment 1228351.0 439000.0 0.93 907709.0 101000.0 0.23 0.8202 0.8554 3117547 ChemDiv3_000790 CCN1/C(=C\2/C(=NN(C2=O)c3ccccc3)C)/C=Cc4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D21 compound treatment 1187603.0 398000.0 0.84 914797.0 108000.0 0.24 0.7706 0.876 1388884 ChemDiv3_000791 O=C(CCOc1ccccc1)NCc2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D22 compound treatment 838422.0 49300.0 0.1 883280.0 76200.0 0.17 0.1965 0.9707 3117548 ChemDiv3_000792 COc1ccccc1/C=C/2\SC(=O)N(CCC(=O)N3c4ccccc4Sc5ccccc35)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D23 mock treatment 1003600.0 214000.0 0.45 998329.0 191000.0 0.43 0.629 0.9998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 D24 mock treatment 649513.0 -140000.0 -0.3 577131.0 -230000.0 -0.52 -0.5789 -0.9637 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E01 compound treatment 528915.0 -260000.0 -0.55 496329.0 -311000.0 -0.71 -0.8896 -0.9925 1583492 ChemDiv3_000793 COC(=O)C1=C(C)NC2=C(C1c3ccc(cc3)N(C)C)C(=O)CC(C2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E02 compound treatment 685458.0 -104000.0 -0.22 690360.0 -117000.0 -0.27 -0.343 -0.9956 1432876 ChemDiv3_000794 CCc1ccc(OCC(=O)Nc2ccc(OC)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E03 compound treatment 1083702.0 295000.0 0.62 1094604.0 288000.0 0.65 0.9039 0.9997 3117549 ChemDiv3_000795 COc1cccc(/C=C/C(=O)C2C(=O)c3ccccc3C2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E04 compound treatment 1197567.0 408000.0 0.87 1059567.0 253000.0 0.57 1.0182 0.9801 1606983 ChemDiv3_000796 Oc1cccc(NC(=O)c2c(O)c3ccccc3n(CC=C)c2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E05 compound treatment 1132720.0 344000.0 0.73 1142992.0 336000.0 0.76 1.0551 0.9997 1715553 ChemDiv3_000797 Cc1[nH]c2ccc(CN3C(=O)c4ccccc4C3=O)cc2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E06 compound treatment 1434162.0 645000.0 1.37 1006101.0 199000.0 0.45 1.2869 0.8935 3020853 ChemDiv3_000798 COC(=O)c1cc(N)c(Cl)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E07 compound treatment 267040.0 -522000.0 -1.11 299544.0 -508000.0 -1.15 -1.5985 -0.9998 1915335 ChemDiv3_000799 FC(F)(F)c1cccc(NC(=O)Nc2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E08 compound treatment 1097649.0 309000.0 0.65 966957.0 160000.0 0.36 0.7196 0.9616 1289585 ChemDiv3_000800 CC1(OC(=O)C2C1C3CCCCC3=C4CCCCC24)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E09 compound treatment 1215298.0 426000.0 0.9 894293.0 87200.0 0.2 0.7791 0.8423 1304126 ChemDiv3_000801 O=C(N1CC(=O)Nc2ccccc12)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E10 compound treatment 1181926.0 393000.0 0.83 1173706.0 367000.0 0.83 1.1783 1.0 1265761 ChemDiv3_000802 COc1cc(nc(OC)n1)N2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E11 compound treatment 1364241.0 575000.0 1.22 1005832.0 199000.0 0.45 1.1817 0.9088 1735414 ChemDiv3_000803 COC(=O)c1ccc(OC(=O)CCN2C(=O)c3ccccc3C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E12 compound treatment 1180023.0 391000.0 0.83 945656.0 139000.0 0.32 0.8088 0.9122 3020873 ChemDiv3_000804 CN(c1ccccc1)S(=O)(=O)c2c(C)cc(C)cc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E13 compound treatment 1142679.0 354000.0 0.75 857028.0 50000.0 0.11 0.6103 0.8051 1517748 ChemDiv3_000805 CN(C1CCCCC1)C(=O)COc2ccc(Cl)c(C)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E14 compound treatment 993410.0 204000.0 0.43 961933.0 155000.0 0.35 0.5552 0.9947 1467248 ChemDiv3_000806 Cc1nc2n(Cc3ccccc3)c4ccccc4n2c1C(=S)Nc5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E15 compound treatment 1303986.0 515000.0 1.09 956874.0 150000.0 0.34 1.0127 0.8856 1918958 ChemDiv3_000807 Clc1cccc(CC2SC(=N)NC2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E16 compound treatment 1245843.0 457000.0 0.97 1027139.0 220000.0 0.5 1.0385 0.9528 3020874 ChemDiv3_000808 CC(/N=C/c1nc2ccccc2n1C)C3(CC4CC5CC(C4)C3)C5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E17 compound treatment 1177993.0 389000.0 0.82 1000691.0 194000.0 0.44 0.8942 0.9568 3117550 ChemDiv3_000809 Cc1ccc(cc1)C(=O)Nc2cccc(c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E18 compound treatment 1370277.0 581000.0 1.23 1099483.0 292000.0 0.66 1.3413 0.9581 3117551 ChemDiv3_000810 COc1ccc(O)c(/C=N/CC(C)\N=C\c2cc(OC)ccc2O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E19 compound treatment 1357944.0 569000.0 1.21 989597.0 183000.0 0.42 1.1462 0.8987 1413824 ChemDiv3_000811 COC(=O)c1ccccc1NC(=O)COc2ccc(OC)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E20 compound treatment 1664679.0 876000.0 1.86 1156222.0 349000.0 0.79 1.8738 0.9282 1629872 ChemDiv3_000812 COc1ccccc1C(=O)Nc2ccc3oc(nc3c2)c4ccc5ccccc5c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E21 compound treatment 1339648.0 551000.0 1.17 888505.0 81400.0 0.19 0.9562 0.8092 1625558 ChemDiv3_000813 COC(=O)c1cccc(NC(=O)c2ccccc2C(=O)O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E22 compound treatment 1032530.0 243000.0 0.52 907440.0 100000.0 0.23 0.5263 0.9327 1326899 ChemDiv3_000814 COc1ccccc1N2CCN(CC2)C(=O)CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E23 mock treatment 948635.0 160000.0 0.34 819385.0 12300.0 0.03 0.259 0.7631 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 E24 mock treatment 506430.0 -283000.0 -0.6 429219.0 -378000.0 -0.86 -1.0312 -0.9845 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F01 compound treatment 466319.0 -323000.0 -0.68 522681.0 -284000.0 -0.65 -0.9411 -0.9996 1373507 ChemDiv3_000815 OC(=O)C1CC=CCC1C(=O)Nc2ccc(Cc3ccncc3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F02 compound treatment 738453.0 -50700.0 -0.11 706111.0 -101000.0 -0.23 -0.2382 -0.9401 3020875 ChemDiv3_000816 O=C(NC1CCCC1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F03 compound treatment 956180.0 167000.0 0.35 826301.0 19200.0 0.04 0.2814 0.7884 1442394 ChemDiv3_000817 O=C(NCCc1ccccc1)c2ccccc2CN3C(=O)c4ccccc4C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F04 compound treatment 1036184.0 247000.0 0.52 855375.0 48300.0 0.11 0.448 0.8372 3020876 ChemDiv3_000818 FC(F)(F)c1nc2ccccc2n1CCOc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F05 compound treatment 1278231.0 489000.0 1.04 704753.0 -102000.0 -0.23 0.5687 0.5352 3117552 ChemDiv3_000819 O=C(N/C(=C/c1ccccc1)/S(=O)(=O)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F06 compound treatment 1115281.0 326000.0 0.69 783515.0 -23500.0 -0.05 0.4511 0.6504 3020877 ChemDiv3_000820 CCOc1ccc(cc1Br)C(=O)Nc2cccc(NC(=O)c3ccccc3)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F07 compound treatment 994739.0 206000.0 0.44 1037936.0 231000.0 0.52 0.6794 0.9957 3117553 ChemDiv3_000821 O=C(Nc1ccccc1)c2cnc[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F08 compound treatment 1041045.0 252000.0 0.53 978967.0 172000.0 0.39 0.654 0.9882 1673072 ChemDiv3_000822 OC(C(=O)Nc1cc(Cl)ccc1Cl)(c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F09 compound treatment 1246258.0 457000.0 0.97 1142099.0 335000.0 0.76 1.2239 0.9929 3020878 ChemDiv3_000823 CCN(CC)c1ccc2cc(C(=O)N)/c(=N/c3cccc(C)c3)/oc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F10 compound treatment 1238651.0 450000.0 0.95 1130268.0 323000.0 0.73 1.1935 0.9917 3117554 ChemDiv3_000824 Fc1ccc(NC(=O)c2cnccn2)c(F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F11 compound treatment 1764379.0 975000.0 2.07 958795.0 152000.0 0.34 1.7059 0.8138 1470949 ChemDiv3_000825 COc1ccc(cc1)c2ccc(OC)cc2C(=O)NN 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F12 compound treatment 1712091.0 923000.0 1.96 962929.0 156000.0 0.35 1.6342 0.8218 1687536 ChemDiv3_000826 CCN(CC)S(=O)(=O)c1ccc(Cl)c(c1)C(=O)Oc2ccc(C)cc2n3nc4ccccc4n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F13 compound treatment 1159898.0 371000.0 0.79 957685.0 151000.0 0.34 0.798 0.9307 1365314 ChemDiv3_000827 Clc1ccc2NC(C3CC=CC3c2c1)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F14 compound treatment 1132097.0 343000.0 0.73 918459.0 111000.0 0.25 0.6932 0.9003 1517186 ChemDiv3_000828 Cc1cccc(c1)C(=O)Nc2ccc(NC(=O)c3ccco3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F15 compound treatment 1075426.0 286000.0 0.61 942213.0 135000.0 0.31 0.6465 0.9502 1513840 ChemDiv3_000829 COC(=O)C1=C(C)N(C(=C(C1c2ccccc2)C(=O)OC)C)c3ccc(OC)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F16 compound treatment 1214979.0 426000.0 0.9 1118526.0 311000.0 0.71 1.1391 0.9928 3117555 ChemDiv3_000830 COc1cccc(/C=C\2/C(=O)NN(C2=O)c3ccccc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F17 compound treatment 1343246.0 554000.0 1.17 1087915.0 281000.0 0.64 1.2822 0.9589 3020879 ChemDiv3_000831 CS(=O)(=O)NCCc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F18 compound treatment 1427257.0 638000.0 1.35 1215339.0 408000.0 0.93 1.613 0.9831 1468720 ChemDiv3_000832 OC(=O)c1ccccc1C(=O)NC=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F19 compound treatment 216955.0 -572000.0 -1.21 212843.0 -594000.0 -1.35 -1.813 -0.9986 3117556 ChemDiv3_000833 CC(C)c1ccc(/C=C/C(=O)NCC=C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F20 compound treatment 1288424.0 499000.0 1.06 1002937.0 196000.0 0.45 1.0634 0.926 3117557 ChemDiv3_000834 CC(C)CNC=C1C(=O)CC(C)(C)CC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F21 compound treatment 1104908.0 316000.0 0.67 859734.0 52700.0 0.12 0.5581 0.8206 1393505 ChemDiv3_000835 Cc1cc(C)cc(NC(=O)c2cc3ccccc3o2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F22 compound treatment 1017479.0 228000.0 0.48 819040.0 12000.0 0.03 0.3616 0.7457 3117558 ChemDiv3_000836 CN1CCN(CC1)C(=O)CCN2C(=O)/C(=C/c3ccc(Cl)cc3)/SC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F23 mock treatment 1113326.0 324000.0 0.69 1075163.0 268000.0 0.61 0.917 0.9982 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 F24 mock treatment 634509.0 -155000.0 -0.33 730550.0 -76500.0 -0.17 -0.3547 -0.9561 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G01 compound treatment 617607.0 -171000.0 -0.36 714055.0 -93000.0 -0.21 -0.4066 -0.9667 1690924 ChemDiv3_000837 COC(=O)C1=C(C)NC2=C(C1c3ccccc3)C(=O)CCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G02 compound treatment 919214.0 130000.0 0.28 935300.0 128000.0 0.29 0.4012 0.9996 1254482 ChemDiv3_000838 Cc1ccc(OCC(=O)NCc2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G03 compound treatment 974727.0 186000.0 0.39 979670.0 173000.0 0.39 0.5557 1.0 1006818 ChemDiv3_000839 OC(=O)CCCC(=O)c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G04 compound treatment 235938.0 -553000.0 -1.17 264637.0 -542000.0 -1.23 -1.7012 -0.9997 3117559 ChemDiv3_000840 CC(C)(C)c1ccc(cc1)C(=O)N2CCCc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G05 compound treatment 1036890.0 248000.0 0.53 1179677.0 373000.0 0.85 0.9705 0.9736 1344674 ChemDiv3_000841 Clc1ccccc1C(=O)c2ccc3OCCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G06 compound treatment 1215118.0 426000.0 0.9 1061842.0 255000.0 0.58 1.0482 0.977 1914993 ChemDiv3_000842 COC(=O)CCC(=O)c1cc(sc1C(C)(C)C)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G07 compound treatment 1265554.0 476000.0 1.01 920973.0 114000.0 0.26 0.8973 0.8606 1342176 ChemDiv3_000843 CC1CCN(Cn2c(=S)oc3ccccc23)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G08 compound treatment 1073538.0 284000.0 0.6 918190.0 111000.0 0.25 0.605 0.9254 1917056 ChemDiv3_000844 FC(F)(F)COc1nc(nc(n1)N2CCCCC2)N(c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G09 compound treatment 200156.0 -589000.0 -1.25 274344.0 -533000.0 -1.21 -1.7393 -0.9999 1584064 ChemDiv3_000845 Cc1ccccc1OCC(=O)NC(c2ccccc2)c3c(O)ccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G10 compound treatment 1277445.0 488000.0 1.04 973571.0 167000.0 0.38 0.9997 0.9069 1318907 ChemDiv3_000846 CCCc1nc(N)c(C#N)c(c1CC)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G11 compound treatment 1710925.0 922000.0 1.95 1316955.0 510000.0 1.16 2.2016 0.9689 1607665 ChemDiv3_000847 O=C(NCCc1ccccc1)c2cc3ccccc3oc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G12 compound treatment 320031.0 -469000.0 -0.99 315736.0 -491000.0 -1.12 -1.493 -0.9983 1316192 ChemDiv3_000848 CCN(Cc1ccccc1)S(=O)(=O)c2cc(Cl)ccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G13 compound treatment 1396179.0 607000.0 1.29 1111065.0 304000.0 0.69 1.3988 0.9575 3117560 ChemDiv3_000849 Clc1ccc(/C=C/C(=O)Nc2nccs2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G14 compound treatment 1428580.0 639000.0 1.36 1094909.0 288000.0 0.65 1.4213 0.9442 1342653 ChemDiv3_000850 Clc1ccc2[nH]c(nc2c1)N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G15 compound treatment 1333955.0 545000.0 1.16 1210261.0 403000.0 0.92 1.4649 0.9934 1360061 ChemDiv3_000851 CCOc1ccccc1C(=O)Nc2cccc(C)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G16 compound treatment 1364475.0 575000.0 1.22 1206796.0 400000.0 0.91 1.5051 0.9895 1160846 ChemDiv3_000852 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(NC(=O)C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G17 compound treatment 1361743.0 573000.0 1.21 1200343.0 393000.0 0.89 1.4907 0.9887 3020907 ChemDiv3_000853 Cc1ccc(NC(=O)c2ccc(F)cc2)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G18 compound treatment 1279124.0 490000.0 1.04 946728.0 140000.0 0.32 0.9591 0.8829 1569529 ChemDiv3_000854 Cc1ccc(NC(=O)c2nc[nH]c2C(=O)N3CCCCC3)c(c1)C(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G19 compound treatment 1108437.0 319000.0 0.68 809198.0 2140.0 0.0 0.4821 0.7122 1657157 ChemDiv3_000855 CC(C)(C)C(=O)NC(c1ccccc1)c2c(O)ccc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G20 compound treatment 1565733.0 777000.0 1.65 1057959.0 251000.0 0.57 1.5675 0.8996 1709867 ChemDiv3_000856 COc1cccc(c1)C(=O)Nc2ccc3oc(nc3c2)c4cccc(I)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G21 compound treatment 1498186.0 709000.0 1.5 1001810.0 195000.0 0.44 1.376 0.8781 1083894 ChemDiv3_000857 Clc1ccc(cc1)C(=O)NCCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G22 compound treatment 1255390.0 466000.0 0.99 1006258.0 199000.0 0.45 1.0192 0.9374 3117561 ChemDiv3_000858 COc1cccc(c1)C(C(F)(F)F)P(=O)(C)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G23 mock treatment 1200973.0 412000.0 0.87 922305.0 115000.0 0.26 0.8027 0.8805 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 G24 mock treatment 806408.0 17300.0 0.04 662778.0 -144000.0 -0.33 -0.206 -0.6242 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H01 compound treatment 573028.0 -216000.0 -0.46 563388.0 -244000.0 -0.55 -0.7156 -0.9955 1366343 ChemDiv3_000859 CC(=O)N(CN1C(=O)C2CC=CCC2C1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H02 compound treatment 944461.0 155000.0 0.33 925319.0 118000.0 0.27 0.423 0.9949 1584378 ChemDiv3_000860 CCOC(=O)Cc1csc(NC(=O)c2ccccc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H03 compound treatment 839465.0 50400.0 0.11 838407.0 31300.0 0.07 0.1259 0.9807 3117562 ChemDiv3_000861 CC(C)c1ccc(C)cc1OCC(=O)/C=C/2\Sc3ccccc3N2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H04 compound treatment 1230257.0 441000.0 0.94 1056850.0 250000.0 0.57 1.0629 0.9714 1622162 ChemDiv3_000862 Cc1ccccc1C(=O)Nc2ccc(NC(=O)c3ccc(cc3)C(C)(C)C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H05 compound treatment 1270464.0 481000.0 1.02 1062492.0 255000.0 0.58 1.1322 0.9643 3117563 ChemDiv3_000863 Cc1ccc(cc1)S(=O)(=O)NN2C(=O)S/C(=C/c3ccccc3)/C2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H06 compound treatment 1181427.0 392000.0 0.83 1052721.0 246000.0 0.56 0.983 0.9812 3020908 ChemDiv3_000864 CSc1ccc(/C=C\2/SC(=O)N(CNc3ccccc3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H07 compound treatment 296716.0 -492000.0 -1.04 285708.0 -521000.0 -1.19 -1.5763 -0.998 1912608 ChemDiv3_000865 Oc1ccc(/N=C/c2c[nH]c3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H08 compound treatment 871308.0 82200.0 0.17 872218.0 65200.0 0.15 0.228 0.9967 1623791 ChemDiv3_000866 Cc1ccc(NC(=O)c2ccc(cc2)c3ccccc3)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H09 compound treatment 1826933.0 1040000.0 2.2 1426859.0 620000.0 1.41 2.5522 0.9768 3117564 ChemDiv3_000867 COc1cccc2cc(c3csc(Nc4cccc(c4)C(F)(F)F)n3)c(=O)oc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H10 compound treatment 778636.0 -10500.0 -0.02 952205.0 145000.0 0.33 0.2176 0.6581 3020909 ChemDiv3_000868 CC(C)(C)c1ccc(cc1)C(=O)Nc2cccc(c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H11 compound treatment 1693050.0 904000.0 1.92 1450831.0 644000.0 1.46 2.39 0.9912 1919894 ChemDiv3_000869 CCS(=O)(=O)C(=C(Nc1ccccc1)Nc2ccccc2)S(=O)(=O)CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H12 compound treatment 1626903.0 838000.0 1.78 1478130.0 671000.0 1.53 2.3347 0.9971 1361150 ChemDiv3_000870 COC(=O)C(C(C)C)N1C(=O)C2C3CC(C=C3)C2C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H13 compound treatment 1584663.0 796000.0 1.69 1876222.0 1070000.0 2.43 2.9114 0.9841 1526618 ChemDiv3_000871 Cc1c(Cl)cccc1NC(=O)c2ccc(cc2)N3C(=O)c4ccccc4C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H14 compound treatment 1305413.0 516000.0 1.09 1211019.0 404000.0 0.92 1.4234 0.9962 3118161 ChemDiv3_000872 O=C(Nc1ccc(cc1)c2nc3c(ccc4ccccc34)o2)c5ccco5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H15 compound treatment 1252076.0 463000.0 0.98 1456714.0 650000.0 1.48 1.7384 0.9803 1157871 ChemDiv3_000873 O=C(COc1ccc2c(cc(=O)oc2c1)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H16 compound treatment 1636868.0 848000.0 1.8 1405671.0 599000.0 1.36 2.2332 0.9906 3118162 ChemDiv3_000874 Nc1nnnn1/N=C\c2ccc(O)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H17 compound treatment 1239637.0 451000.0 0.96 1652191.0 845000.0 1.92 2.034 0.9479 1288630 ChemDiv3_000875 CCOC(=O)c1ccccc1NS(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H18 compound treatment 849644.0 60500.0 0.13 908812.0 102000.0 0.23 0.2543 0.9614 1696480 ChemDiv3_000876 Cc1ccc(NCC(O)Cn2c3ccccc3c4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H19 compound treatment 1111300.0 322000.0 0.68 1230942.0 424000.0 0.96 1.1644 0.9858 1434081 ChemDiv3_000877 CC(C)c1ccc(OCC(=O)NCC=C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H20 compound treatment 1196730.0 408000.0 0.86 1155380.0 348000.0 0.79 1.171 0.9991 3020910 ChemDiv3_000878 CC1(C)CC(=O)C(=CNCc2ccco2)C(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H21 compound treatment 1286705.0 498000.0 1.05 1223340.0 416000.0 0.95 1.4151 0.9985 1350794 ChemDiv3_000879 COc1ccc(OC(=O)c2cc3ccccc3o2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H22 compound treatment 1223713.0 435000.0 0.92 1315184.0 508000.0 1.16 1.4684 0.9937 3020911 ChemDiv3_000880 O=c1[nH]nc(N2CCOCC2)c(=O)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H23 mock treatment 1176218.0 387000.0 0.82 1265392.0 458000.0 1.04 1.3171 0.993 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 H24 mock treatment 777555.0 -11600.0 -0.02 813202.0 6140.0 0.01 -0.0074 -0.2641 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I01 compound treatment 560931.0 -228000.0 -0.48 577571.0 -229000.0 -0.52 -0.711 -0.9993 1682167 ChemDiv3_000881 CCOC(=O)C1=C(NC(=O)NC1c2ccc(OC)cc2)c3ccc(OC)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I02 compound treatment 1043049.0 254000.0 0.54 988329.0 181000.0 0.41 0.6721 0.9913 3020912 ChemDiv3_000882 C1CN(CCO1)c2ccc(C=Nn3cncn3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I03 compound treatment 793505.0 4400.0 0.01 805382.0 -1680.0 0.0 0.0039 0.3865 1588286 ChemDiv3_000883 CCOc1ccccc1N2C(=O)C3C(C(C=CC3c4ccccc4)c5ccccc5)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I04 compound treatment 1098455.0 309000.0 0.66 1054420.0 247000.0 0.56 0.8614 0.9971 3118163 ChemDiv3_000884 Cc1ccc(C)c(c1)S(=O)(=O)NCCCn2ccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I05 compound treatment 1266271.0 477000.0 1.01 1141206.0 334000.0 0.76 1.2525 0.99 1319250 ChemDiv3_000885 O=C(Nc1ccc2-c3ccc(NC(=O)C4CCCCC4)cc3S(=O)(=O)c2c1)C5CCCCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I06 compound treatment 1469228.0 680000.0 1.44 1064290.0 257000.0 0.58 1.4331 0.921 3020913 ChemDiv3_000886 CC1NC(=O)NC1CCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I07 compound treatment 1453405.0 664000.0 1.41 1156055.0 349000.0 0.79 1.5569 0.9632 1370690 ChemDiv3_000887 CCC1CCCCN1C(=O)CN2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I08 compound treatment 1401947.0 613000.0 1.3 1208352.0 401000.0 0.91 1.5638 0.985 3020914 ChemDiv3_000888 CCC1(CC)Cc2ccccc2/C(=N/c3c(C)n(C)n(c4ccccc4)c3=O)/N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I09 compound treatment 1628505.0 839000.0 1.78 1353271.0 546000.0 1.24 2.1364 0.9845 3118164 ChemDiv3_000889 CC(C)CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc3cccc(c3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I10 compound treatment 1234381.0 445000.0 0.94 1231117.0 424000.0 0.96 1.3492 0.9999 3118165 ChemDiv3_000890 COc1ccc(Cl)cc1NC(=O)c2nc3nc(cc(n3n2)C(F)(F)F)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I11 compound treatment 1607269.0 818000.0 1.73 1290173.0 483000.0 1.1 2.0031 0.9757 1696086 ChemDiv3_000891 CCc1ccc(OCC(=O)N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I12 compound treatment 1896850.0 1110000.0 2.35 1268557.0 461000.0 1.05 2.4025 0.934 1643226 ChemDiv3_000892 OC(=O)CP(=O)(O)c1ccc(Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I13 compound treatment 1934112.0 1150000.0 2.43 1410488.0 603000.0 1.37 2.6865 0.9635 3118166 ChemDiv3_000893 Clc1ccccc1/C=C/C(=O)N2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I14 compound treatment 1396153.0 607000.0 1.29 1200713.0 394000.0 0.89 1.5428 0.9842 3020915 ChemDiv3_000894 COc1ccccc1/C=N\c2ccc3n(Cc4ccccc4)c(C)nc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I15 compound treatment 1756206.0 967000.0 2.05 1203419.0 396000.0 0.9 2.0869 0.9319 1438926 ChemDiv3_000895 COC(=O)c1ccccc1NC(=O)c2ccccc2Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I16 compound treatment 1952808.0 1160000.0 2.47 1284855.0 478000.0 1.09 2.5126 0.9321 1126074 ChemDiv3_000896 O=S(=O)(Cc1ccccc1)Nc2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I17 compound treatment 1471006.0 682000.0 1.45 1262435.0 455000.0 1.04 1.7543 0.9866 3118167 ChemDiv3_000897 Clc1ccc(/C=C/C(=O)NCc2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I18 compound treatment 1650957.0 862000.0 1.83 1263336.0 456000.0 1.04 2.0255 0.964 3118168 ChemDiv3_000898 O=C1CS/C(=N\c2ccccc2)/N1Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I19 compound treatment 1390212.0 601000.0 1.27 1019343.0 212000.0 0.48 1.2424 0.9117 1496753 ChemDiv3_000899 CC(=O)n1cc(c2ccncc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I20 compound treatment 1482826.0 694000.0 1.47 1145021.0 338000.0 0.77 1.5832 0.9542 3118169 ChemDiv3_000900 CC(=O)NC(=O)c/1cc2ccccc2o\c1=N/c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I21 compound treatment 1051642.0 263000.0 0.56 904983.0 97900.0 0.22 0.551 0.9191 1085397 ChemDiv3_000901 Clc1ccccc1NC(=O)COc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I22 compound treatment 1327010.0 538000.0 1.14 1171925.0 365000.0 0.83 1.3929 0.9878 3020938 ChemDiv3_000902 CP(=O)(O)C(c1cccc(Cl)c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I23 mock treatment 1392447.0 603000.0 1.28 1098902.0 292000.0 0.66 1.3736 0.9533 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 I24 mock treatment 737130.0 -52000.0 -0.11 792993.0 -14100.0 -0.03 -0.1005 -0.8762 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J01 compound treatment 680176.0 -109000.0 -0.23 597727.0 -209000.0 -0.48 -0.4998 -0.9449 3118170 ChemDiv3_000903 O=C1NC(=O)/C(=C\c2c3ccccc3cc4ccccc24)/C(=O)N1c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J02 compound treatment 1087323.0 298000.0 0.63 1034640.0 228000.0 0.52 0.8129 0.9951 1538193 ChemDiv3_000904 Cc1cccc(Nc2nc(C)cc(C)c2C#N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J03 compound treatment 1052496.0 263000.0 0.56 917571.0 111000.0 0.25 0.5725 0.935 3020939 ChemDiv3_000905 CC(C)C(=O)/C=C\1/Sc2ccccc2N1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J04 compound treatment 838648.0 49500.0 0.11 727558.0 -79500.0 -0.18 -0.0535 -0.2561 1399642 ChemDiv3_000906 CC(C)(C#CC(O)(c1ccccc1)c2ccccc2)N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J05 compound treatment 1383573.0 594000.0 1.26 1111587.0 305000.0 0.69 1.3807 0.9602 3118171 ChemDiv3_000907 Clc1ccc(/C=C\2/SC(=O)N(NC(=O)c3ccccc3Cl)C2=S)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J06 compound treatment 1410361.0 621000.0 1.32 1088060.0 281000.0 0.64 1.383 0.9448 1545446 ChemDiv3_000908 OC(=O)c1ccccc1n2c(=O)c3cc4c(=O)n(c5ccccc5C(=O)O)c(=O)c4cc3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J07 compound treatment 1310065.0 521000.0 1.1 973277.0 166000.0 0.38 1.0482 0.8979 1642929 ChemDiv3_000909 C(N1CCN(Cc2ccccc2)C1c3c[nH]c4ccccc34)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J08 compound treatment 1254627.0 466000.0 0.99 997263.0 190000.0 0.43 1.0036 0.9315 3118172 ChemDiv3_000910 FC(F)(F)c1cccc(NC(=O)c2ccc(cc2)c3ccccc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J09 compound treatment 1685817.0 897000.0 1.9 1379359.0 572000.0 1.3 2.2643 0.9829 3020940 ChemDiv3_000911 Ic1cccc(/C=N/N2C(=O)C3C4C=CC(C3C2=O)C54CC5)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J10 compound treatment 1380124.0 591000.0 1.25 1214472.0 407000.0 0.93 1.5409 0.989 3118173 ChemDiv3_000912 Cc1cc(I)ccc1NC(=O)c2ccc(cc2)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J11 compound treatment 1446496.0 657000.0 1.39 1352387.0 545000.0 1.24 1.8621 0.9983 1477505 ChemDiv3_000913 CCCS(=O)(=O)c1c(C(=O)OC)n2ccccc2c1S(=O)(=O)CCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J12 compound treatment 1394597.0 605000.0 1.28 1564280.0 757000.0 1.72 2.125 0.9895 1130176 ChemDiv3_000914 Cc1cccc(NCN2C(=O)C3C4CC(C=C4)C3C2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J13 compound treatment 1716840.0 928000.0 1.97 1442983.0 636000.0 1.45 2.413 0.9885 3020941 ChemDiv3_000915 O=C/1OC(=N\C1=C/Nc2ccccn2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J14 compound treatment 1726434.0 937000.0 1.99 1618031.0 811000.0 1.84 2.7088 0.9993 1478515 ChemDiv3_000916 CCCOc1ccc(cc1)C(=O)Nc2ccc(cc2)c3nc4ccccc4o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J15 compound treatment 1198131.0 409000.0 0.87 1083156.0 276000.0 0.63 1.057 0.9874 3118174 ChemDiv3_000917 CC(C)(C)NC(=O)CCCN1C(=O)/C(=C/c2ccccc2)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J16 compound treatment 1451319.0 662000.0 1.4 1330780.0 524000.0 1.19 1.8346 0.9966 3020942 ChemDiv3_000918 Brc1ccc(cc1)C2=N/C(=C\Nc3ccccc3)/C(=O)O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J17 compound treatment 1608548.0 819000.0 1.74 1457718.0 651000.0 1.48 2.2744 0.9968 3118175 ChemDiv3_000919 OC(=O)CCCNc1n[nH]c(=O)[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J18 compound treatment 1456491.0 667000.0 1.41 1483278.0 676000.0 1.54 2.0875 0.9991 1721267 ChemDiv3_000920 O=C1N(CN2CCCCC2)C(=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J19 compound treatment 1255190.0 466000.0 0.99 1178694.0 372000.0 0.84 1.2961 0.997 1065790 ChemDiv3_000921 COc1ccc(NC(=S)NC2CCCCC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J20 compound treatment 1291368.0 502000.0 1.06 1213465.0 406000.0 0.92 1.4063 0.9975 1923178 ChemDiv3_000922 CC1(C)CC(=O)C(=CNCC2CCCO2)C(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J21 compound treatment 1238089.0 449000.0 0.95 1133552.0 326000.0 0.74 1.1979 0.9924 1623304 ChemDiv3_000923 Cc1ccc(OC(=O)c2cc3ccccc3o2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J22 compound treatment 1116229.0 327000.0 0.69 1158744.0 352000.0 0.8 1.0557 0.9975 3118176 ChemDiv3_000924 CCOCc1c[nH]c(=O)[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J23 mock treatment 861976.0 72900.0 0.15 1155198.0 348000.0 0.79 0.6689 0.8295 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 J24 mock treatment 550891.0 -238000.0 -0.51 937172.0 130000.0 0.3 -0.1479 -0.2527 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K01 compound treatment 560795.0 -228000.0 -0.48 624463.0 -183000.0 -0.42 -0.6358 -0.9971 1216806 ChemDiv3_000925 CC(=O)OCCn1c(=O)[nH]c(=O)c2nsnc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K02 compound treatment 690421.0 -98700.0 -0.21 897661.0 90600.0 0.21 -0.0023 -0.0078 3118177 ChemDiv3_000926 CC(C)(C)c1cc(Cl)c(O)c(/N=C/c2ccccc2O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K03 compound treatment 696239.0 -92900.0 -0.2 878866.0 71800.0 0.16 -0.0238 -0.093 1915945 ChemDiv3_000927 CCOC(=O)/C=C(\C)/N1N=C2C(CCc3cc(OC)ccc23)C1c4ccc(OC)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K04 compound treatment 965705.0 177000.0 0.37 1180261.0 373000.0 0.85 0.8647 0.9324 1496403 ChemDiv3_000928 Cc1cn(cn1)S(=O)(=O)c2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K05 compound treatment 809214.0 20100.0 0.04 805649.0 -1410.0 0.0 0.0279 0.652 1637460 ChemDiv3_000929 CCOc1cc(ccc1O)c2cc(C)c3c(ccc4ccccc43)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K06 compound treatment 998353.0 209000.0 0.44 1057952.0 251000.0 0.57 0.717 0.9923 3020943 ChemDiv3_000930 CCC1=C/C(=C/N(C)c2ccccc2)/C(=O)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K07 compound treatment 1044010.0 255000.0 0.54 1162128.0 355000.0 0.81 0.9529 0.981 1083865 ChemDiv3_000931 FC(F)(F)c1cccc(NC(=O)c2ccco2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K08 compound treatment 1053506.0 264000.0 0.56 1116324.0 309000.0 0.7 0.8935 0.9937 1678628 ChemDiv3_000932 NCCCc1nc2cc3ccccc3cc2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K09 compound treatment 1239138.0 450000.0 0.95 1310130.0 503000.0 1.14 1.4834 0.9959 3118178 ChemDiv3_000933 CN(C)c1n[nH]c(=O)[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K10 compound treatment 1201225.0 412000.0 0.87 1456166.0 649000.0 1.48 1.6613 0.9687 1535139 ChemDiv3_000934 NC(=O)C1CCN(CC1)S(=O)(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K11 compound treatment 1458606.0 669000.0 1.42 1528608.0 722000.0 1.64 2.1636 0.9974 3020944 ChemDiv3_000935 NN1C(=O)/C(=C\c2ccccc2)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K12 compound treatment 1415747.0 627000.0 1.33 1656941.0 850000.0 1.93 2.3057 0.9833 1729835 ChemDiv3_000936 C(Cn1c(Cc2ccccc2)nc3ccccc13)N4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K13 compound treatment 1396984.0 608000.0 1.29 1408557.0 601000.0 1.37 1.8782 0.9996 3020945 ChemDiv3_000937 CC1CCN(CC1)C(=O)/C=C/c2ccc3OCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K14 compound treatment 1447082.0 658000.0 1.39 1594906.0 788000.0 1.79 2.2529 0.9924 3118311 ChemDiv3_000938 Cc1nc2cc(/N=C\c3ccc(Cl)cc3)ccc2n1Cc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K15 compound treatment 222028.0 -567000.0 -1.2 243764.0 -563000.0 -1.28 -1.7557 -0.9995 3020946 ChemDiv3_000939 CCCCc1ccc(NC(=O)CC)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K16 compound treatment 1494713.0 706000.0 1.5 1351481.0 544000.0 1.24 1.933 0.9956 1129901 ChemDiv3_000940 O=S(=O)(Cc1ccccc1)Nn2cnnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K17 compound treatment 1080141.0 291000.0 0.62 1217042.0 410000.0 0.93 1.0954 0.9799 3020947 ChemDiv3_000941 CC(NC(=O)/C=C/c1ccccc1Cl)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K18 compound treatment 1213102.0 424000.0 0.9 1226315.0 419000.0 0.95 1.3096 0.9996 3020310 ChemDiv3_000942 CCOc1ccc(OCCSc2nc3ccccc3n2Cc4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K19 compound treatment 1269574.0 480000.0 1.02 1291364.0 484000.0 1.1 1.4988 0.9992 1632334 ChemDiv3_000943 CCOC(=O)c1ccccc1NC(=O)C2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K20 compound treatment 1091220.0 302000.0 0.64 1115969.0 309000.0 0.7 0.9495 0.9989 3118312 ChemDiv3_000944 CCOc1cccc2cc(C(=O)N)/c(=N/Cc3ccccc3)/oc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K21 compound treatment 1206662.0 418000.0 0.89 1276510.0 469000.0 1.07 1.3806 0.9957 1564768 ChemDiv3_000945 COC(=O)c1cccc(NC(=O)COc2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K22 compound treatment 455463.0 -334000.0 -0.71 509145.0 -298000.0 -0.68 -0.9791 -0.9998 1122886 ChemDiv3_000946 COC(=O)C1=C(C)NC(=O)CC1c2ccccc2I 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K23 mock treatment 963419.0 174000.0 0.37 1035540.0 228000.0 0.52 0.6286 0.9861 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 K24 mock treatment 557200.0 -232000.0 -0.49 826051.0 19000.0 0.04 -0.3171 -0.6425 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L01 compound treatment 496520.0 -293000.0 -0.62 568018.0 -239000.0 -0.54 -0.8229 -0.9978 1725902 ChemDiv3_000947 CCOC(=O)CSc1nc2ccccc2o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L02 compound treatment 939770.0 151000.0 0.32 990315.0 183000.0 0.42 0.5205 0.9914 3118313 ChemDiv3_000948 Clc1cccc(c1)C2OCC3(CO2)COC(OC3)c4cccc(Cl)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L03 compound treatment 983809.0 195000.0 0.41 1013263.0 206000.0 0.47 0.6234 0.998 3020311 ChemDiv3_000949 Clc1ccc(/C=C\2/C=C(OC2=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L04 compound treatment 1084426.0 295000.0 0.63 1068981.0 262000.0 0.6 0.8638 0.9997 1215566 ChemDiv3_000950 COc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L05 compound treatment 1169807.0 381000.0 0.81 943358.0 136000.0 0.31 0.7898 0.9136 1482448 ChemDiv3_000951 Clc1ccc(OCC(=O)NC2CCS(=O)(=O)C2)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L06 compound treatment 1371407.0 582000.0 1.23 1005112.0 198000.0 0.45 1.1913 0.9066 3118314 ChemDiv3_000952 O=C1CCC(=O)N1c2nccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L07 compound treatment 1236661.0 448000.0 0.95 1037767.0 231000.0 0.52 1.0418 0.9609 1240764 ChemDiv3_000953 Oc1ccccc1C2N(Cc3ccccc3)CCN2Cc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L08 compound treatment 1150010.0 361000.0 0.77 1123227.0 316000.0 0.72 1.0493 0.9995 1351151 ChemDiv3_000954 Clc1c(sc2ccccc12)C(=O)NCc3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L09 compound treatment 1215434.0 426000.0 0.9 1066988.0 260000.0 0.59 1.0569 0.9788 1921190 ChemDiv3_000955 Nc1nnc(CCS(=O)(=O)c2ccc(Br)cc2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L10 compound treatment 1224657.0 436000.0 0.92 1108342.0 301000.0 0.68 1.1373 0.9892 1668007 ChemDiv3_000956 O=C(Nc1cccnc1)c2cc3ccccc3oc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L11 compound treatment 1292919.0 504000.0 1.07 1280551.0 473000.0 1.08 1.5164 1.0 3118315 ChemDiv3_000957 CN1CNC(=NS(=O)(=O)c2ccc(C)cc2)NC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L12 compound treatment 1275435.0 486000.0 1.03 1389382.0 582000.0 1.32 1.6652 0.9924 1733849 ChemDiv3_000958 COC(=O)c1ccc(NC(=O)C2C(C3CCC2C3)C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L13 compound treatment 1621337.0 832000.0 1.76 1326211.0 519000.0 1.18 2.0822 0.9809 3020312 ChemDiv3_000959 O=C/1OC(=N\C1=C/N2CCCCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L14 compound treatment 1397733.0 609000.0 1.29 1300650.0 494000.0 1.12 1.7059 0.9976 1222654 ChemDiv3_000960 CCCOc1ccc(cc1)C(=O)Nc2ccc-3c(Cc4ccccc43)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L15 compound treatment 1136388.0 347000.0 0.74 1237926.0 431000.0 0.98 1.2133 0.9901 3020313 ChemDiv3_000961 Cc1cccc(/N=C/2\SCC(=O)N2c3cccc(C)c3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L16 compound treatment 850101.0 61000.0 0.13 832033.0 25000.0 0.06 0.1316 0.9317 3118316 ChemDiv3_000962 COC(=O)CNC(c1ccccc1)c2cc(Br)ccc2NC(=O)CCN3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L17 compound treatment 879829.0 90700.0 0.19 1019210.0 212000.0 0.48 0.4771 0.9187 3020314 ChemDiv3_000963 CCCOC(=O)c1ccc(NC(=O)/C=C/c2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L18 compound treatment 1043546.0 254000.0 0.54 1283760.0 477000.0 1.08 1.1478 0.9481 3118317 ChemDiv3_000964 CCCCN1C(=O)/C(=C/N(C(=O)C)c2ccccc2)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L19 compound treatment 1107145.0 318000.0 0.67 1231458.0 424000.0 0.96 1.159 0.9846 1677249 ChemDiv3_000965 CCc1cccc(C)c1NC(=O)C2COc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L20 compound treatment 1162039.0 373000.0 0.79 1092537.0 285000.0 0.65 1.018 0.9952 3118318 ChemDiv3_000966 COc1ccc(CNC=C2C(=O)CC(C)(C)CC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L21 compound treatment 1211850.0 423000.0 0.9 1172457.0 365000.0 0.83 1.2211 0.9993 3118319 ChemDiv3_000967 Clc1ccc(/C=C/2\SC(=O)N(CC(=O)Nc3cccnc3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L22 compound treatment 1059499.0 270000.0 0.57 1194293.0 387000.0 0.88 1.0279 0.9784 3020315 ChemDiv3_000968 CN(/C(=N\S(=O)(=O)c1ccc(C)cc1)/c2ccccc2)c3ccc(O)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L23 mock treatment 948233.0 159000.0 0.34 1056123.0 249000.0 0.57 0.6389 0.9694 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 L24 mock treatment 567452.0 -222000.0 -0.47 792107.0 -15000.0 -0.03 -0.3563 -0.7563 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M01 compound treatment 474181.0 -315000.0 -0.67 556563.0 -250000.0 -0.57 -0.8748 -0.9969 3118320 ChemDiv3_000969 OC(=O)c1ccc(/N=C/c2cn(Cc3ccccc3)c4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M02 compound treatment 947593.0 158000.0 0.34 1025025.0 218000.0 0.5 0.588 0.9821 3020316 ChemDiv3_000970 Fc1ccc(cc1)c2nc3cc(/N=C/C=C/c4ccc5OCOc5c4)ccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M03 compound treatment 985997.0 197000.0 0.42 1086972.0 280000.0 0.64 0.7451 0.9791 3118321 ChemDiv3_000971 COc1ccc2CC/C(=C\c3ccc(cc3)N(C)C)/C(=O)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M04 compound treatment 975237.0 186000.0 0.39 1306189.0 499000.0 1.13 1.0814 0.9001 1918339 ChemDiv3_000972 CC(C)(C)S(=O)(=O)c1ccc(s1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M05 compound treatment 997138.0 208000.0 0.44 1112268.0 305000.0 0.69 0.8025 0.9761 1679374 ChemDiv3_000973 CCc1ccc(cc1)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M06 compound treatment 1063771.0 275000.0 0.58 1211288.0 404000.0 0.92 1.0616 0.9758 3118322 ChemDiv3_000974 CCC1=C/C(=C\c2ccc3OCOc3c2)/C(=O)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M07 compound treatment 1308155.0 519000.0 1.1 1221395.0 414000.0 0.94 1.4442 0.997 3118323 ChemDiv3_000975 Brc1ccc2NC(=O)/C(=C/3\SC(=S)N(C3=O)c4cccc(Br)c4)/c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M08 compound treatment 1058680.0 270000.0 0.57 1239178.0 432000.0 0.98 1.0988 0.9668 1260425 ChemDiv3_000976 OC(=O)c1cncc(OC(=O)OCc2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M09 compound treatment 1241637.0 453000.0 0.96 1192087.0 385000.0 0.88 1.2973 0.999 1445337 ChemDiv3_000977 O=C(CCN1C(=O)c2ccccc2C1=O)Nc3ccc(cc3)S(=O)(=O)Nc4nccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M10 compound treatment 1235479.0 446000.0 0.95 1362060.0 555000.0 1.26 1.5614 0.9899 1228370 ChemDiv3_000978 COc1ccc(cc1)S(=O)(=O)N2CCCCC2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M11 compound treatment 1194297.0 405000.0 0.86 1231313.0 424000.0 0.96 1.2894 0.9983 1353970 ChemDiv3_000979 CCS(=O)(=O)c1ccc(O)c(NC(=O)COc2ccc(OC)cc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M12 compound treatment 1227859.0 439000.0 0.93 1282831.0 476000.0 1.08 1.4226 0.9972 3020317 ChemDiv3_000980 Brc1ccc(/C=N/c2nc3ccccc3n2CCN4CCCCC4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M13 compound treatment 1488079.0 699000.0 1.48 1365587.0 559000.0 1.27 1.9457 0.997 1731333 ChemDiv3_000981 CCOC(=O)c1cccc(NC(=O)c2ccccc2Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M14 compound treatment 1450382.0 661000.0 1.4 1286934.0 480000.0 1.09 1.7627 0.9923 3020318 ChemDiv3_000982 CN(C)c1ccc(/C=N/c2ccc3n(cnc3c2)c4ccc(C)cc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M15 compound treatment 1308299.0 519000.0 1.1 1314774.0 508000.0 1.15 1.5945 0.9997 1678613 ChemDiv3_000983 CCOc1ccccc1C(=O)Nc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M16 compound treatment 1132726.0 344000.0 0.73 1361243.0 554000.0 1.26 1.406 0.9661 1685159 ChemDiv3_000984 CC1CC(C)CN(C1)C(=O)c2c(C)onc2c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M17 compound treatment 974723.0 186000.0 0.39 1249636.0 443000.0 1.01 0.9897 0.9161 3020319 ChemDiv3_000985 CC(NC(=O)/C=C/c1ccc2OCOc2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M18 compound treatment 1159640.0 371000.0 0.79 1452290.0 645000.0 1.47 1.5927 0.9572 3118324 ChemDiv3_000986 CCOc1ccc(OCCSc2nc(=O)cc(C)[nH]2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M19 compound treatment 1366973.0 578000.0 1.23 1549476.0 742000.0 1.69 2.0598 0.9876 1635077 ChemDiv3_000987 NC(=O)CCN1C(=O)c2ccccc2C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M20 compound treatment 1212089.0 423000.0 0.9 1297897.0 491000.0 1.12 1.4232 0.9941 1419414 ChemDiv3_000988 C(CN1CCOCC1)Cc2ccc(COc3ccccc3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M21 compound treatment 643873.0 -145000.0 -0.31 767922.0 -39100.0 -0.09 -0.2806 -0.8756 1606786 ChemDiv3_000989 COC(=O)c1ccccc1NC(=O)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M22 compound treatment 886874.0 97800.0 0.21 994202.0 187000.0 0.43 0.4474 0.9454 1273253 ChemDiv3_000990 CNS(=O)(=O)c1ccc-2c(c1)C(=NO)c3cc(ccc32)S(=O)(=O)NC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M23 mock treatment 1092998.0 304000.0 0.64 1160633.0 354000.0 0.8 1.024 0.994 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 M24 mock treatment 573115.0 -216000.0 -0.46 751520.0 -55500.0 -0.13 -0.4131 -0.8696 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N01 compound treatment 503397.0 -286000.0 -0.61 545910.0 -261000.0 -0.59 -0.8481 -1.0 1426304 ChemDiv3_000991 Cc1cc(C)cc(OC(=O)CCN2C(=O)c3ccccc3C2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N02 compound treatment 980236.0 191000.0 0.41 1033504.0 226000.0 0.51 0.6505 0.993 3020320 ChemDiv3_000992 Brc1ccc(cc1)C2OCC(CO2)OC(=O)c3ccc(Br)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N03 compound treatment 972105.0 183000.0 0.39 1039547.0 232000.0 0.53 0.6481 0.9884 1721013 ChemDiv3_000993 Clc1ccc(cc1Cl)C(=O)NCCc2nc3ccccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N04 compound treatment 1142836.0 354000.0 0.75 1254103.0 447000.0 1.02 1.2489 0.9888 3020321 ChemDiv3_000994 Brc1ccc(cc1)S(=O)(=O)/N=C(\Nc2ccccc2)/c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N05 compound treatment 1039467.0 250000.0 0.53 1123888.0 317000.0 0.72 0.8846 0.9887 1559580 ChemDiv3_000995 CCOC(=O)C1=C(C)N(C)C(=O)NC1c2ccccc2OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N06 compound treatment 1168356.0 379000.0 0.8 1326432.0 519000.0 1.18 1.4035 0.9825 3020344 ChemDiv3_000996 CSc1ccc(/C=c\2/sc3nc4c(C)c(C)ccc4n3c2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N07 compound treatment 1058757.0 270000.0 0.57 1144704.0 338000.0 0.77 0.947 0.9895 1921413 ChemDiv3_000997 CC(=O)Nc1ccc(NC(=O)/C=C/c2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N08 compound treatment 969563.0 180000.0 0.38 1057042.0 250000.0 0.57 0.6724 0.9814 1649360 ChemDiv3_000998 CC(C)c1ccc(NC(=O)c2cccnc2Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N09 compound treatment 1183045.0 394000.0 0.84 1200637.0 394000.0 0.89 1.2233 0.9994 1551746 ChemDiv3_000999 CC(=O)Nc1nnc(CCS(=O)(=O)c2ccc(C)cc2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N10 compound treatment 1168113.0 379000.0 0.8 1322888.0 516000.0 1.17 1.3974 0.983 3118325 ChemDiv3_001000 Oc1ccccc1NC(=S)NC(=O)/C=C/c2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N11 compound treatment 1308750.0 520000.0 1.1 1329919.0 523000.0 1.19 1.6195 0.9993 3118597 ChemDiv3_001001 NC(=NS(=O)(=O)c1ccc(NC(=O)OC2CCCC2)cc1)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N12 compound treatment 1414527.0 625000.0 1.33 1521613.0 715000.0 1.62 2.0863 0.9949 1270195 ChemDiv3_001002 CC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)OCC(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N13 compound treatment 1334711.0 546000.0 1.16 1442370.0 635000.0 1.44 1.8392 0.9939 3118453 ChemDiv3_001003 O=S(=O)(/N=C(\OC1CCCCC1)/c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N14 compound treatment 1333845.0 545000.0 1.15 1320915.0 514000.0 1.17 1.6427 1.0 1241887 ChemDiv3_001004 CCCOc1cccc(c1)C(=O)Nc2ccc(cc2)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N15 compound treatment 1052777.0 264000.0 0.56 1004768.0 198000.0 0.45 0.7131 0.9942 3020346 ChemDiv3_001005 COc1ccccc1N2C(=O)S/C(=C\c3ccccc3)/C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N16 compound treatment 1207518.0 418000.0 0.89 1309982.0 503000.0 1.14 1.4357 0.9921 1373892 ChemDiv3_001006 CC(=C)Cn1c(SCC(=O)NN)nc2ccccc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N17 compound treatment 1300246.0 511000.0 1.08 1464921.0 658000.0 1.5 1.8238 0.9875 1493653 ChemDiv3_001007 CC(C)c1ccccc1NC(=O)c2cc3ccccc3oc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N18 compound treatment 1266911.0 478000.0 1.01 1483890.0 677000.0 1.54 1.8043 0.9794 3118454 ChemDiv3_001008 CC(=O)N(/C=C/1\SC(=S)N(Cc2ccccc2)C1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N19 compound treatment 1474440.0 685000.0 1.45 1426169.0 619000.0 1.41 2.0226 0.9999 1232650 ChemDiv3_001009 CCOC(=O)c1cccc(NC(=O)CCOc2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N20 compound treatment 1436937.0 648000.0 1.37 1128397.0 321000.0 0.73 1.4877 0.9564 3118455 ChemDiv3_001010 CC1(C)CC(=O)C(=CNCc2cccnc2)C(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N21 compound treatment 1473817.0 685000.0 1.45 1150502.0 343000.0 0.78 1.5785 0.9577 3118456 ChemDiv3_001011 CN1CCN(CC1)NC(=O)CN2C(=O)S/C(=C/c3ccc(Cl)cc3)/C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N22 compound treatment 865128.0 76000.0 0.16 1130351.0 323000.0 0.74 0.6337 0.8421 1118985 ChemDiv3_001012 COc1ccccc1NC(=O)C2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N23 mock treatment 987091.0 198000.0 0.42 1000677.0 194000.0 0.44 0.6081 0.9997 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 N24 mock treatment 543120.0 -246000.0 -0.52 710329.0 -96700.0 -0.22 -0.5243 -0.9263 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O01 compound treatment 130314.0 -659000.0 -1.4 181698.0 -625000.0 -1.42 -1.9929 -1.0 3118457 ChemDiv3_001013 COC(=O)CNC(c1ccccc1)c2cc(Br)ccc2NC(=O)c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O02 compound treatment 508122.0 -281000.0 -0.6 513197.0 -294000.0 -0.67 -0.8936 -0.9984 3020347 ChemDiv3_001014 OC(=O)c1ccc(cc1)c2ccc(/C=C/3\Sc4ccccc4C3=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O03 compound treatment 934836.0 146000.0 0.31 1009168.0 202000.0 0.46 0.5434 0.9813 1433689 ChemDiv3_001015 COc1ccc(cc1OC)C2CC(=NN2C=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O04 compound treatment 402302.0 -387000.0 -0.82 553152.0 -254000.0 -0.58 -0.988 -0.9852 1216374 ChemDiv3_001016 CC1(C)CC(=CC(C)(C)N1)c2ccc(s2)C3=CC(C)(C)NC(C)(C)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O05 compound treatment 783227.0 -5880.0 -0.01 694580.0 -112000.0 -0.26 -0.1896 -0.7407 1687051 ChemDiv3_001017 Oc1cccc(c1)c2nc3ccc4ccccc4c3c5CCCCc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O06 compound treatment 1106961.0 318000.0 0.67 1148088.0 341000.0 0.78 1.0247 0.9976 3020348 ChemDiv3_001018 CCc1cc2c[n+](sc2s1)C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O07 compound treatment 1428863.0 640000.0 1.36 1290095.0 483000.0 1.1 1.7356 0.9945 1282936 ChemDiv3_001019 Cc1cc(=O)oc2cc(OCC(=O)O)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O08 compound treatment 1226048.0 437000.0 0.93 1358512.0 551000.0 1.25 1.5415 0.9889 1606633 ChemDiv3_001020 CC(=O)Oc1cncc(c1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O09 compound treatment 1343150.0 554000.0 1.17 1197171.0 390000.0 0.89 1.4577 0.9904 1192059 ChemDiv3_001021 O=C(NCc1ccccc1)C(Cc2ccccc2)N3C(=O)c4ccccc4C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O10 compound treatment 1172290.0 383000.0 0.81 1904344.0 1100000.0 2.49 2.3384 0.8913 1475559 ChemDiv3_001022 COc1ccc(cc1)C(=O)NCC#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O11 compound treatment 1414940.0 626000.0 1.33 1156374.0 349000.0 0.79 1.4997 0.9699 1080178 ChemDiv3_001023 Clc1ccc(cc1)C(=O)NC(=S)Nc2ccccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O12 compound treatment 1341797.0 553000.0 1.17 1292355.0 485000.0 1.1 1.6087 0.9995 3118458 ChemDiv3_001024 Clc1ccc(/C=N/c2nc3ccccc3n2CC=C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O13 compound treatment 1398396.0 609000.0 1.29 1220127.0 413000.0 0.94 1.5774 0.9877 1649330 ChemDiv3_001025 O=C(CNC(=O)c1ccccc1)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O14 compound treatment 1449035.0 660000.0 1.4 1234462.0 427000.0 0.97 1.6764 0.9841 3118459 ChemDiv3_001026 COc1ccccc1n2cnc3cc(/N=C/c4ccccc4O)ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O15 compound treatment 1538900.0 750000.0 1.59 1300628.0 494000.0 1.12 1.9174 0.9855 1328150 ChemDiv3_001027 Cc1ccc(cc1)N(C2CS(=O)(=O)CC2OC(=O)c3ccccc3)C(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O16 compound treatment 1425886.0 637000.0 1.35 1377401.0 570000.0 1.3 1.8715 0.9998 1283075 ChemDiv3_001028 COc1ccc(NC(=O)CN2C(=O)c3ccccc3C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O17 compound treatment 1457597.0 668000.0 1.42 1316394.0 509000.0 1.16 1.8209 0.995 3118460 ChemDiv3_001029 Cc1ccccc1NC(=O)/C=C/c2ccc3OCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O18 compound treatment 1501201.0 712000.0 1.51 1372343.0 565000.0 1.29 1.9762 0.9968 1317231 ChemDiv3_001030 NNC(=O)CNC(=O)C1COc2ccccc2O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O19 compound treatment 1543138.0 754000.0 1.6 1211906.0 405000.0 0.92 1.7812 0.9656 1195157 ChemDiv3_001031 COc1ccc(CCNC(=O)C(C(C)C)N2C(=O)c3ccccc3C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O20 compound treatment 1657078.0 868000.0 1.84 1191730.0 385000.0 0.87 1.9195 0.9422 3020350 ChemDiv3_001032 OC(=O)C/1=NN(C(=O)\C1=C/c2c[nH]c3ccccc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O21 compound treatment 1350233.0 561000.0 1.19 1046586.0 240000.0 0.54 1.2262 0.9373 1154870 ChemDiv3_001033 COc1ccc(NC(=O)COc2ccc(C)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O22 compound treatment 731471.0 -57600.0 -0.12 1109100.0 302000.0 0.69 0.3992 0.5723 1195792 ChemDiv3_001034 CCNS(=O)(=O)c1ccc-2c(c1)C(=O)c3cc(ccc32)S(=O)(=O)NCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O23 mock treatment 910995.0 122000.0 0.26 1032117.0 225000.0 0.51 0.5445 0.9499 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 O24 mock treatment 431499.0 -358000.0 -0.76 452856.0 -354000.0 -0.81 -1.1055 -0.9995 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P01 compound treatment 345975.0 -443000.0 -0.94 420743.0 -386000.0 -0.88 -1.2853 -0.9994 1266216 ChemDiv3_001035 Cc1cccc(C)c1OC(=O)CN2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P02 compound treatment 468394.0 -321000.0 -0.68 473405.0 -334000.0 -0.76 -1.0172 -0.9985 3118461 ChemDiv3_001036 Cc1ccccc1OCCn2c(S)nc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P03 compound treatment 543272.0 -246000.0 -0.52 664988.0 -142000.0 -0.32 -0.5969 -0.9735 1270060 ChemDiv3_001037 O=C(NC1CCCC1)c2cc3nc(cc(c4ccccc4)n3n2)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P04 compound treatment 550394.0 -239000.0 -0.51 656626.0 -150000.0 -0.34 -0.5997 -0.9818 3020351 ChemDiv3_001038 Cc1ccccc1N/C(=N\S(=O)(=O)c2ccccc2)/c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P05 compound treatment 613678.0 -175000.0 -0.37 708548.0 -98500.0 -0.22 -0.4213 -0.9705 1725017 ChemDiv3_001039 COc1ccc(CC(C)CC(=O)Nc2ccc(I)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P06 compound treatment 1032891.0 244000.0 0.52 1041595.0 235000.0 0.53 0.7425 0.9999 1202851 ChemDiv3_001040 Nc1c(C#N)c(c(C#N)c2nc3ccccc3n12)c4ccccc4Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P07 compound treatment 124599.0 -665000.0 -1.41 111498.0 -696000.0 -1.58 -2.1143 -0.9983 1528263 ChemDiv3_001041 COc1ccc(NCC(O)Cn2c3ccc(Cl)cc3c4cc(Cl)ccc24)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P08 compound treatment 638147.0 -151000.0 -0.32 877649.0 70600.0 0.16 -0.1128 -0.3151 1730700 ChemDiv3_001042 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3Br)cc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P09 compound treatment 480946.0 -308000.0 -0.65 682973.0 -124000.0 -0.28 -0.6614 -0.9295 3020380 ChemDiv3_001043 COc1ccc-2c(c1)C(=NN)c3cc(OC)ccc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P10 compound treatment 809705.0 20600.0 0.04 978068.0 171000.0 0.39 0.3058 0.7816 3118462 ChemDiv3_001044 OC(=O)CCN1C(=O)/C(=C/c2ccc(o2)c3ccc(Cl)cc3Cl)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P11 compound treatment 710516.0 -78600.0 -0.17 766433.0 -40600.0 -0.09 -0.1831 -0.9613 1544835 ChemDiv3_001045 CC(C)OC(=O)N1CCN(CC1)S(=O)(=O)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P12 compound treatment 666910.0 -122000.0 -0.26 818820.0 11800.0 0.03 -0.1643 -0.6308 3118463 ChemDiv3_001046 CCN1/C(=C\2/SC(=S)N(N)C2=O)/C=Cc3cc(C)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P13 compound treatment 539156.0 -250000.0 -0.53 606659.0 -200000.0 -0.46 -0.6969 -0.9972 3118464 ChemDiv3_001047 CCS(=O)(=O)CCc1nnc(NC(=O)Nc2cccc(c2)C(F)(F)F)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P14 compound treatment 369886.0 -419000.0 -0.89 436683.0 -370000.0 -0.84 -1.2239 -0.9996 1403310 ChemDiv3_001048 CCOc1ccc(NC(=O)c2cc3ccccc3o2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P15 compound treatment 818862.0 29800.0 0.06 1109920.0 303000.0 0.69 0.5315 0.7687 3118465 ChemDiv3_001049 COc1ccc(/C=C/2\SC(=O)N(C2=O)c3ccc(C)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P16 compound treatment 725588.0 -63500.0 -0.13 1097453.0 290000.0 0.66 0.3716 0.5515 3020381 ChemDiv3_001050 CN(C)c1ccc(/C=C/c2ccncc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P17 compound treatment 751134.0 -38000.0 -0.08 917702.0 111000.0 0.25 0.1209 0.4579 1724755 ChemDiv3_001051 CCc1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P18 compound treatment 648536.0 -141000.0 -0.3 964035.0 157000.0 0.36 0.0416 0.0896 3020382 ChemDiv3_001052 CN1C(=O)/C(=C/Nc2ccccc2)/OC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P19 compound treatment 666576.0 -123000.0 -0.26 721351.0 -85700.0 -0.19 -0.3215 -0.99 1157486 ChemDiv3_001053 Cc1cccc(NC(=O)CCOc2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P20 compound treatment 599860.0 -189000.0 -0.4 621374.0 -186000.0 -0.42 -0.5822 -0.9997 1218521 ChemDiv3_001054 CCOP(=S)(OCC)SCSn1c(=O)oc2cc(Cl)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P21 compound treatment 627270.0 -162000.0 -0.34 670363.0 -137000.0 -0.31 -0.4624 -0.9988 3118466 ChemDiv3_001055 O=C/1N(C(=S)S\C1=C\c2cccs2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P22 compound treatment 556769.0 -232000.0 -0.49 606932.0 -200000.0 -0.46 -0.67 -0.9992 3020383 ChemDiv3_001056 CC(Oc1ccc(Br)cc1)C(=O)NN 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P23 mock treatment 505605.0 -284000.0 -0.6 511904.0 -295000.0 -0.67 -0.8995 -0.9985 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2003 P24 mock treatment 439774.0 -349000.0 -0.74 406292.0 -401000.0 -0.91 -1.168 -0.9947 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A01 compound treatment 333143.0 -273000.0 -0.58 536036.0 -104000.0 -0.24 -0.5759 -0.9214 1702421 ChemDiv3_001057 CCc1nccn1C(=O)CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A02 compound treatment 436792.0 -169000.0 -0.36 517643.0 -122000.0 -0.28 -0.4501 -0.9918 1479194 ChemDiv3_001058 Clc1ccc(cc1)C(=O)Nc2cc3ccccc3oc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A03 compound treatment 457654.0 -149000.0 -0.31 586462.0 -53200.0 -0.12 -0.3082 -0.9135 1673755 ChemDiv3_001059 Cc1ccc(cc1NC(=O)c2ccccc2)c3nc4ccccc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A04 compound treatment 386457.0 -220000.0 -0.47 585159.0 -54500.0 -0.12 -0.417 -0.865 3118598 ChemDiv3_001060 CC1=Nc2ccc(cc2C1(C)C)C(F)(F)F.[O-][N+](=O)c1cc([N+](=O)[O-])c([O-])c(c1)[N+](=O)[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A05 compound treatment 541928.0 -64300.0 -0.14 612866.0 -26800.0 -0.06 -0.1394 -0.9339 1545532 ChemDiv3_001061 Cc1ccccc1NC(=O)CCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A06 compound treatment 546644.0 -59600.0 -0.13 639765.0 141.0 0.0 -0.0891 -0.7053 1235446 ChemDiv3_001062 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)Oc3ccccc3)S(=O)(=O)c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A07 compound treatment 448712.0 -158000.0 -0.33 508383.0 -131000.0 -0.3 -0.4471 -0.9984 3118599 ChemDiv3_001063 CC1C(Cc2ccc(C)cc2)C(=O)N(C1=O)c3cccc(c3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A08 compound treatment 553882.0 -52300.0 -0.11 523357.0 -116000.0 -0.26 -0.2654 -0.9257 1351878 ChemDiv3_001064 CC(C)(C)c1cc(c(O)c(c1)C(C)(C)C)n2nc3ccccc3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A09 compound treatment 526376.0 -79800.0 -0.17 712113.0 72500.0 0.16 -0.0032 -0.0134 1662979 ChemDiv3_001065 CCCc1cc2c(=O)c(c(C)oc2cc1OC(=O)C)c3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A10 compound treatment 682603.0 76400.0 0.16 692181.0 52600.0 0.12 0.199 0.9888 1457143 ChemDiv3_001066 Cc1ccc(cc1)S(=O)(=O)N2C(C3CC2C=C3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A11 compound treatment 513045.0 -93200.0 -0.2 701456.0 61800.0 0.14 -0.0403 -0.1661 3020384 ChemDiv3_001067 O=C/1OC(=N\C1=C/C=C/c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A12 compound treatment 536275.0 -69900.0 -0.15 642315.0 2690.0 0.01 -0.1005 -0.6774 3118600 ChemDiv3_001068 Clc1ccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(Cl)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A13 compound treatment 420719.0 -186000.0 -0.39 594115.0 -45500.0 -0.1 -0.3512 -0.8637 3020385 ChemDiv3_001069 CC(C)n1c(nc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A14 compound treatment 621786.0 15600.0 0.03 688328.0 48700.0 0.11 0.1016 0.8796 1226119 ChemDiv3_001070 Brc1ccc(NC(=O)C2(CC3CC4CC(C3)C2)C4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A15 compound treatment 666537.0 60300.0 0.13 849976.0 210000.0 0.48 0.4286 0.8657 3020386 ChemDiv3_001071 N#Cc1c(/N=C/c2ccccc2)sc3CCCCc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A16 compound treatment 368995.0 -237000.0 -0.5 582309.0 -57300.0 -0.13 -0.4478 -0.8619 3118601 ChemDiv3_001072 CCC1=Nc2ccc(Br)cc2C(N1CC(=O)NN)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A17 compound treatment 450100.0 -156000.0 -0.33 540775.0 -98800.0 -0.22 -0.3929 -0.9822 1259740 ChemDiv3_001073 COc1ccc(cc1)C(=O)COC(=O)CN2C(=O)C3CC=CCC3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A18 compound treatment 156515.0 -450000.0 -0.95 134456.0 -505000.0 -1.15 -1.4863 -0.9957 3020387 ChemDiv3_001074 CC[n+]1c(/C=C/N(C)c2ccccc2)sc3ccc(OC)cc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A19 compound treatment 438600.0 -168000.0 -0.36 637331.0 -2290.0 -0.01 -0.255 -0.7174 1267587 ChemDiv3_001075 CCOc1ccc2nc(ccc2c1)C3(CC4CC5CC(C4)C3)C5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A20 compound treatment 246858.0 -359000.0 -0.76 264729.0 -375000.0 -0.85 -1.1414 -0.9984 3020388 ChemDiv3_001076 CCN1/C(=C/C2=CC(=O)CC(C)(C)C2)/Sc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A21 compound treatment 474356.0 -132000.0 -0.28 573677.0 -65900.0 -0.15 -0.3037 -0.9573 3118602 ChemDiv3_001077 Cc1n[nH]c(=S)n(/N=C/c2ccccc2)c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A22 compound treatment 427740.0 -178000.0 -0.38 482598.0 -157000.0 -0.36 -0.52 -0.9996 1512849 ChemDiv3_001078 COc1ccccc1OC(C)C(=O)NN 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A23 mock treatment 404952.0 -201000.0 -0.43 441068.0 -199000.0 -0.45 -0.6209 -0.9996 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 A24 mock treatment 438467.0 -168000.0 -0.36 373160.0 -266000.0 -0.61 -0.6799 -0.9678 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B01 compound treatment 713128.0 107000.0 0.23 811812.0 172000.0 0.39 0.4371 0.9662 3118603 ChemDiv3_001079 Cc1cccn2c(=O)c(/C=N/c3ccc(Cl)cc3)c(NCCO)nc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B02 compound treatment 814915.0 209000.0 0.44 539098.0 -101000.0 -0.23 0.1512 0.3037 1487953 ChemDiv3_001080 COC(=O)c1c(NC(=O)C(C)C)sc2CCCc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B03 compound treatment 958921.0 353000.0 0.75 887176.0 248000.0 0.56 0.9267 0.9902 1608654 ChemDiv3_001081 COC(=O)C1=C(CCS1)NC(=O)c2ccc(cc2)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B04 compound treatment 722471.0 116000.0 0.25 648145.0 8520.0 0.02 0.188 0.7604 1203988 ChemDiv3_001082 Cc1ccc(C)n1c2cccc(N)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B05 compound treatment 947287.0 341000.0 0.72 982131.0 343000.0 0.78 1.0619 0.9993 1593401 ChemDiv3_001083 CCCCn1c(S)nc2n(C)c(=O)[nH]c(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B06 compound treatment 1022741.0 417000.0 0.88 1006062.0 366000.0 0.83 1.2135 0.9996 3020389 ChemDiv3_001084 OC(=O)c1ccc(/C=C\2/C(=O)NC(=O)N(C2=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B07 compound treatment 733367.0 127000.0 0.27 604202.0 -35400.0 -0.08 0.1336 0.4751 1483637 ChemDiv3_001085 COc1cc(cc(OC)c1OC)C(=O)N=C2C(=CC(=O)C=C2C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B08 compound treatment 892050.0 286000.0 0.61 663884.0 24300.0 0.06 0.4675 0.7683 1211323 ChemDiv3_001086 COc1ccc(CNc2ccc(F)cc2C)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B09 compound treatment 1100748.0 495000.0 1.05 1096737.0 457000.0 1.04 1.4762 1.0 1504008 ChemDiv3_001087 OC(=O)c1cccc(Nc2nc(c3ccccc3)c4ccccc4n2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B10 compound treatment 865196.0 259000.0 0.55 998419.0 359000.0 0.82 0.965 0.9814 1495584 ChemDiv3_001088 CC1(C)Cc2c(C#N)c(NC(=O)C(c3ccccc3)c4ccccc4)sc2CO1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B11 compound treatment 1034628.0 428000.0 0.91 934159.0 295000.0 0.67 1.1157 0.9888 1679056 ChemDiv3_001089 COc1ccc(cc1)c2nc3ccc4ccccc4c3c5CCCCc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B12 compound treatment 879516.0 273000.0 0.58 729000.0 89400.0 0.2 0.5534 0.9013 3118604 ChemDiv3_001090 CC(C)(C)/N=c\1/cccccc1NCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B13 compound treatment 829427.0 223000.0 0.47 876757.0 237000.0 0.54 0.7158 0.9979 3020431 ChemDiv3_001091 CC1=C/C(=C/c2ccco2)/C(=O)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B14 compound treatment 1133249.0 527000.0 1.12 1097165.0 458000.0 1.04 1.5256 0.9994 1567047 ChemDiv3_001092 COc1cc(cc(OC)c1OC)C2NCCS2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B15 compound treatment 1022297.0 416000.0 0.88 1034172.0 395000.0 0.9 1.258 1.0 3118605 ChemDiv3_001093 Cn1c(=O)n(C)c2ncn(C=C)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B16 compound treatment 254000.0 -352000.0 -0.75 222923.0 -417000.0 -0.95 -1.1979 -0.9931 1521623 ChemDiv3_001094 Cc1ccccc1OCC(O)Cn2c3ccccc3c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B17 compound treatment 923926.0 318000.0 0.67 849330.0 210000.0 0.48 0.8134 0.9857 3020432 ChemDiv3_001095 Oc1ccccc1c2cc(cc(n2)c3ccccc3)c4ccc5OCOc5c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B18 compound treatment 1057397.0 451000.0 0.96 1026037.0 386000.0 0.88 1.2975 0.9991 1643074 ChemDiv3_001096 CN(C)c1ccc(cc1)C2C(N3C(=O)c4ccccc4C3=O)C(=O)N2c5ccc(C)c(Cl)c5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B19 compound treatment 713203.0 107000.0 0.23 688508.0 48900.0 0.11 0.239 0.9461 1726140 ChemDiv3_001097 CC1(C)Cc2c(sc3ncn4nc(COc5ccc(Cl)cc5)nc4c23)C(C)(C)N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B20 compound treatment 544959.0 -61300.0 -0.13 591546.0 -48100.0 -0.11 -0.1691 -0.9963 1237367 ChemDiv3_001098 O=C(C1c2ccccc2Oc3ccccc13)N4CCc5ccccc45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B21 compound treatment 650801.0 44600.0 0.09 792548.0 153000.0 0.35 0.3127 0.8678 3020434 ChemDiv3_001099 CC(C)(C)OC(=O)NC(=N)n1cccn1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B22 compound treatment 599617.0 -6610.0 -0.01 768902.0 129000.0 0.29 0.1979 0.6726 1449384 ChemDiv3_001100 COc1ccccc1NC(=O)c2cccc(c2)S(=O)(=O)N3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B23 mock treatment 549247.0 -57000.0 -0.12 663904.0 24300.0 0.06 -0.0464 -0.3492 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 B24 mock treatment 437185.0 -169000.0 -0.36 494317.0 -145000.0 -0.33 -0.487 -0.9992 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C01 compound treatment 502288.0 -104000.0 -0.22 621914.0 -17700.0 -0.04 -0.1843 -0.8227 1056652 ChemDiv3_001101 CC(C)(C)NC(=O)c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C02 compound treatment 955840.0 350000.0 0.74 726277.0 86700.0 0.2 0.6634 0.865 1434405 ChemDiv3_001102 O=C(COc1ccc2ccccc2c1)Oc3ccc(cc3)C(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C03 compound treatment 1112772.0 507000.0 1.07 906247.0 267000.0 0.61 1.188 0.9634 1247192 ChemDiv3_001103 CC(C)(C)c1ccc(cc1)C(=O)Nc2ccc(NC(=O)c3ccccc3F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C04 compound treatment 545138.0 -61100.0 -0.13 554647.0 -85000.0 -0.19 -0.2282 -0.9811 3020435 ChemDiv3_001104 COc1ccc(cc1)c2cs/c(=N\c3ccccc3)/n2CCCN(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C05 compound treatment 1028940.0 423000.0 0.9 829205.0 190000.0 0.43 0.9384 0.9437 1348473 ChemDiv3_001105 O=C(Nc1cccc2ccccc12)C3(CC4CC5CC(C4)C3)C5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C06 compound treatment 1254707.0 648000.0 1.37 1052476.0 413000.0 0.94 1.6358 0.9827 1500590 ChemDiv3_001106 O=C(Nc1cc2c(ccc3ccccc32)oc1=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C07 compound treatment 1078107.0 472000.0 1.0 960508.0 321000.0 0.73 1.2232 0.988 1484356 ChemDiv3_001107 CCN(CC)C(=S)SCc1cn2cccc(C)c2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C08 compound treatment 884048.0 278000.0 0.59 746452.0 107000.0 0.24 0.5882 0.9233 3020436 ChemDiv3_001108 O=C(Nc1ccc(C#N)cc1)/C=C/c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C09 compound treatment 782636.0 176000.0 0.37 840619.0 201000.0 0.46 0.5876 0.995 1425597 ChemDiv3_001109 CCOC(=O)c1ccc(o1)c2coc3cc(OC(=O)C)c(CC)cc3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C10 compound treatment 1199505.0 593000.0 1.26 1081229.0 442000.0 1.0 1.5993 0.9938 3118606 ChemDiv3_001110 O=C(Nc1ccccc1)/C(=C/c2ccccc2)/NC(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C11 compound treatment 1067603.0 461000.0 0.98 936037.0 296000.0 0.67 1.1681 0.9835 3020437 ChemDiv3_001111 COc1ccccc1/C=C/C/2=N/C(=C\c3ccc4OCOc4c3)/C(=O)O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C12 compound treatment 1316412.0 710000.0 1.51 909364.0 270000.0 0.61 1.4982 0.9216 3118607 ChemDiv3_001112 Cc1ccc(cc1)N2C(=O)NC(=O)/C(=C\c3ccccc3)/C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C13 compound treatment 824977.0 219000.0 0.46 743189.0 104000.0 0.24 0.4944 0.9506 1917708 ChemDiv3_001113 Sc1nc2ccccc2n1Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C14 compound treatment 511676.0 -94500.0 -0.2 475771.0 -164000.0 -0.37 -0.4051 -0.9577 1591681 ChemDiv3_001114 Cc1cc(C)c2C3C=CCC3C(N4CC5CC=CC5c1c42)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C15 compound treatment 952944.0 347000.0 0.74 836156.0 197000.0 0.45 0.8357 0.9715 3118901 ChemDiv3_001115 Cc1sc(/N=C/c2cn(Cc3ccccc3)c4ccccc24)c(C#N)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C16 compound treatment 1169755.0 564000.0 1.19 940640.0 301000.0 0.68 1.3287 0.965 3118746 ChemDiv3_001116 CSc1ccc(/C=N/N(C)S(=O)(=O)c2ccc(C)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C17 compound treatment 1175852.0 570000.0 1.21 894176.0 255000.0 0.58 1.2631 0.9433 1358774 ChemDiv3_001117 Clc1ccc(cc1)C(=O)COC(=O)C2CC=CCC2C(=O)OCC(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C18 compound treatment 236280.0 -370000.0 -0.78 222759.0 -417000.0 -0.95 -1.2247 -0.9956 3118747 ChemDiv3_001118 CC[n+]1ccccc1/C=C/N(C(=O)C)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C19 compound treatment 1132832.0 527000.0 1.12 890172.0 251000.0 0.57 1.1922 0.9512 1915904 ChemDiv3_001119 O=C1NC(=O)/C(=C\c2ccco2)/C(=O)N1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C20 compound treatment 1031742.0 426000.0 0.9 811140.0 172000.0 0.39 0.9136 0.9296 3118748 ChemDiv3_001120 Cc1cc(NS(=O)(=O)c2ccc(/N=C/c3ccccc3O)cc2)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C21 compound treatment 953768.0 348000.0 0.74 858605.0 219000.0 0.5 0.873 0.9818 3020438 ChemDiv3_001121 Cc1n[nH]c(=S)n(/N=C/C=C/c2ccccc2)c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C22 compound treatment 1000580.0 394000.0 0.84 836250.0 197000.0 0.45 0.9073 0.957 1314862 ChemDiv3_001122 CC(Oc1ccc2ccccc2c1)C(=O)NN 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C23 mock treatment 842759.0 237000.0 0.5 752368.0 113000.0 0.26 0.5358 0.9515 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 C24 mock treatment 533136.0 -73100.0 -0.15 454085.0 -186000.0 -0.42 -0.4078 -0.9076 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D01 compound treatment 604669.0 -1560.0 0.0 1041009.0 401000.0 0.91 0.643 0.7045 3020439 ChemDiv3_001123 Clc1ccc(cc1)c2ncc3ccccn23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D02 compound treatment 527022.0 -79200.0 -0.17 696784.0 57200.0 0.13 -0.0268 -0.1264 1146210 ChemDiv3_001124 CN(C)CCNc1cnn(c2ccccc2)c(=O)c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D03 compound treatment 805022.0 199000.0 0.42 836579.0 197000.0 0.45 0.6146 0.9995 1432100 ChemDiv3_001125 COC(=O)C1=C(CCS1)NC(=O)c2ccc(cc2)S(=O)(=O)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D04 compound treatment 817672.0 211000.0 0.45 896564.0 257000.0 0.58 0.73 0.9914 1339626 ChemDiv3_001126 OC(=O)CCC(=O)Nc1sc2CCCCc2c1C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D05 compound treatment 860691.0 254000.0 0.54 723589.0 84000.0 0.19 0.5164 0.9025 1228834 ChemDiv3_001127 CCCCc1c(O)nc(SCCN(C)C)n(c2ccccc2)c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D06 compound treatment 979980.0 374000.0 0.79 930466.0 291000.0 0.66 1.0278 0.996 3020440 ChemDiv3_001128 OC(=O)COc1c(Cl)cc(C=C2C(=O)NC(=S)NC2=O)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D07 compound treatment 612723.0 6500.0 0.01 600575.0 -39000.0 -0.09 -0.053 -0.5903 1175621 ChemDiv3_001129 Cc1c(Cl)c(O)c(Cl)c(C)c1N(S(=O)(=O)c2ccccc2)S(=O)(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D08 compound treatment 995281.0 389000.0 0.82 1180102.0 540000.0 1.23 1.4521 0.9812 1419799 ChemDiv3_001130 COc1ccc(CNCc2cccc(OC)c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D09 compound treatment 968011.0 362000.0 0.77 1096755.0 457000.0 1.04 1.2772 0.9888 1117976 ChemDiv3_001131 CCOC(=O)c1cc2ccc(OCc3ccccc3)cc2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D10 compound treatment 996675.0 390000.0 0.83 1115681.0 476000.0 1.08 1.3506 0.9912 1501667 ChemDiv3_001132 COC(=O)c1ccc(Oc2nc(OC)nc(n2)N(C)C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D11 compound treatment 203854.0 -402000.0 -0.85 225580.0 -414000.0 -0.94 -1.2688 -0.9988 3118749 ChemDiv3_001133 COc1ccc(cc1)C(=O)N2N3ON=C(N3c4ccccc24)c5c(C)cc(C)cc5C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D12 compound treatment 1143334.0 537000.0 1.14 1073124.0 434000.0 0.99 1.5021 0.9974 1634877 ChemDiv3_001134 Cc1nc(=O)c(c(C)n1c2ccc(cc2)C(=O)O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D13 compound treatment 989328.0 383000.0 0.81 1119647.0 480000.0 1.09 1.346 0.9894 3118750 ChemDiv3_001135 COc1ccc(OC)c(c1)c2cc(on2)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D14 compound treatment 1008592.0 402000.0 0.85 975506.0 336000.0 0.76 1.1431 0.9985 1149659 ChemDiv3_001136 Cc1cc(nn1C(CC(=O)O)C(=O)O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D15 compound treatment 838620.0 232000.0 0.49 746321.0 107000.0 0.24 0.5199 0.9467 3020658 ChemDiv3_001137 Cn1c(=O)n(Cc2ccccc2)c(=O)c3n(Cc4ccccc4)c(Cl)nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D16 compound treatment 1018073.0 412000.0 0.87 963486.0 324000.0 0.74 1.138 0.9964 1680766 ChemDiv3_001138 NS(=O)(=O)c1ccc(NC(=O)C2CC=CCC2C(=O)N3CCOCC3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D17 compound treatment 298656.0 -308000.0 -0.65 391764.0 -248000.0 -0.56 -0.8595 -0.9974 1707287 ChemDiv3_001139 COc1ccc(cc1)c2nc(=O)c3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D18 compound treatment 1029884.0 424000.0 0.9 974888.0 335000.0 0.76 1.1741 0.9967 3118751 ChemDiv3_001140 Cc1nc2ccccc2c(=O)n1NC(=O)/C=C/c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D19 compound treatment 956716.0 350000.0 0.74 993704.0 354000.0 0.81 1.0946 0.9992 1655686 ChemDiv3_001141 C(Oc1ccccc1)c2nc3c4c5CCCCc5sc4ncn3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D20 compound treatment 737631.0 131000.0 0.28 592229.0 -47400.0 -0.11 0.1208 0.4044 1270051 ChemDiv3_001142 CCN(C(=O)C1c2ccccc2Oc3ccccc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D21 compound treatment 814368.0 208000.0 0.44 805608.0 166000.0 0.38 0.5789 0.997 3020662 ChemDiv3_001143 CC(C)(C)N1Sc2ccccc2NC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D22 compound treatment 799781.0 194000.0 0.41 849069.0 209000.0 0.48 0.6269 0.9973 1371498 ChemDiv3_001144 Clc1ccc(NC(=O)c2cccc(c2)S(=O)(=O)N3CCCCCC3)nc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D23 mock treatment 748844.0 143000.0 0.3 845253.0 206000.0 0.47 0.5444 0.9778 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 D24 mock treatment 539420.0 -66800.0 -0.14 561849.0 -77800.0 -0.18 -0.2252 -0.9939 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E01 compound treatment 450773.0 -155000.0 -0.33 550091.0 -89500.0 -0.2 -0.377 -0.9732 3020664 ChemDiv3_001145 NN(CCC#N)C1=NS(=O)(=O)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E02 compound treatment 601530.0 -4690.0 -0.01 644316.0 4690.0 0.01 5.0E-4 0.0347 1565298 ChemDiv3_001146 Cc1ccc(OCC(=O)NC2CCS(=O)(=O)C2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E03 compound treatment 707332.0 101000.0 0.21 830955.0 191000.0 0.44 0.4592 0.9468 1023964 ChemDiv3_001147 O=c1cc(ss1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E04 compound treatment 890940.0 285000.0 0.6 851070.0 211000.0 0.48 0.7667 0.9936 1128679 ChemDiv3_001148 OC(=O)C1CCCN(C1)S(=O)(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E05 compound treatment 836204.0 230000.0 0.49 862589.0 223000.0 0.51 0.7032 0.9998 3020666 ChemDiv3_001149 NC(=O)c1cccc(/N=C/c2cccc(Cl)c2Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E06 compound treatment 547781.0 -58400.0 -0.12 752278.0 113000.0 0.26 0.0935 0.3286 1433984 ChemDiv3_001150 COC(=O)C1=C(C)NC2=C(C1c3ccccc3)C(=O)CC(C2)c4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E07 compound treatment 773318.0 167000.0 0.35 775319.0 136000.0 0.31 0.4686 0.9976 1622867 ChemDiv3_001151 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)Nc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E08 compound treatment 829900.0 224000.0 0.47 857213.0 218000.0 0.49 0.6851 0.9998 3118752 ChemDiv3_001152 CC(C)c1cc(C(C)C)c(N)c(c1)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E09 compound treatment 895173.0 289000.0 0.61 880404.0 241000.0 0.55 0.8202 0.9984 3020668 ChemDiv3_001153 CC(C)OC(=O)CCN1C(=O)/C(=C/c2ccccc2)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E10 compound treatment 920129.0 314000.0 0.67 1009011.0 369000.0 0.84 1.0644 0.9934 1484844 ChemDiv3_001154 CC(=O)Nc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E11 compound treatment 925751.0 320000.0 0.68 999251.0 360000.0 0.82 1.0571 0.9956 1314682 ChemDiv3_001155 O=C(Nc1nccs1)c2cccc(c2)S(=O)(=O)N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E12 compound treatment 1055951.0 450000.0 0.95 1010247.0 371000.0 0.84 1.27 0.9981 3020722 ChemDiv3_001156 COc1cc(/C=C\2/S/C(=N\c3cc(C)cc(C)c3)/NC2=O)cc(Br)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E13 compound treatment 1070351.0 464000.0 0.98 959496.0 320000.0 0.73 1.21 0.9889 1326481 ChemDiv3_001157 Sc1nnc(CCn2c3ccccc3c4ccccc24)n1CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E14 compound treatment 994579.0 388000.0 0.82 988757.0 349000.0 0.79 1.1434 0.9998 3020724 ChemDiv3_001158 Cc1ccc(cc1)c2nnc(SCC=C)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E15 compound treatment 815952.0 210000.0 0.44 963368.0 324000.0 0.74 0.8349 0.9709 1337418 ChemDiv3_001159 O=S(=O)(N1CCCCC1)c2ccc3ccccc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E16 compound treatment 786392.0 180000.0 0.38 882371.0 243000.0 0.55 0.6603 0.9838 3020725 ChemDiv3_001160 CN(/N=C/c1cccc(Br)c1)S(=O)(=O)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E17 compound treatment 899220.0 293000.0 0.62 950673.0 311000.0 0.71 0.9393 0.9979 1502789 ChemDiv3_001161 Cc1ccc(cc1)C(=O)Nc2cc3ccccc3oc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E18 compound treatment 873092.0 267000.0 0.57 752398.0 113000.0 0.26 0.5813 0.9359 1562439 ChemDiv3_001162 OCCc1c(c2ccccc2)n(Cc3ccccc3)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E19 compound treatment 588154.0 -18100.0 -0.04 768232.0 129000.0 0.29 0.1797 0.6093 1347662 ChemDiv3_001163 CC(NC(=O)COc1ccccc1C(C)(C)C)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E20 compound treatment 451260.0 -155000.0 -0.33 546124.0 -93500.0 -0.21 -0.3826 -0.9778 3118753 ChemDiv3_001164 OC(=O)/C=C/C(=O)Nc1sc2CCCc2c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E21 compound treatment 669948.0 63700.0 0.14 773251.0 134000.0 0.3 0.3103 0.9334 1411190 ChemDiv3_001165 COC(=O)C1=C(C)NC(=C(C1c2ccc(cc2)C(C)C)C(=O)OC)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E22 compound treatment 475949.0 -130000.0 -0.28 549255.0 -90400.0 -0.21 -0.3406 -0.9894 3118754 ChemDiv3_001166 COc1ccc(/C=C/C(=O)Nc2ccc(N3CCOCC3)c(Cl)c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E23 mock treatment 469368.0 -137000.0 -0.29 544296.0 -95300.0 -0.22 -0.3584 -0.9897 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 E24 mock treatment 431058.0 -175000.0 -0.37 520519.0 -119000.0 -0.27 -0.4541 -0.988 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F01 compound treatment 388997.0 -217000.0 -0.46 388595.0 -251000.0 -0.57 -0.7292 -0.9943 1523805 ChemDiv3_001167 Clc1ccc(cc1Cl)c2csc(NC(=O)C3CC3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F02 compound treatment 695509.0 89300.0 0.19 654803.0 15200.0 0.03 0.1582 0.8225 1457223 ChemDiv3_001168 COc1ccccc1NC(=O)CSc2nc3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F03 compound treatment 665529.0 59300.0 0.13 619672.0 -20000.0 -0.05 0.0568 0.4252 1694096 ChemDiv3_001169 Cc1nc2cc(NC(=O)c3ccc(cc3)N4C(=O)CCC4=O)ccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F04 compound treatment 866790.0 261000.0 0.55 840570.0 201000.0 0.46 0.7136 0.9956 1719103 ChemDiv3_001170 CCC1(CC)Cc2ccccc2-c3nc4SCCn4c(=O)c31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F05 compound treatment 964145.0 358000.0 0.76 838740.0 199000.0 0.45 0.8566 0.9695 1784397 ChemDiv3_001171 CCCCc1c(O)nc(SCCC(=O)O)[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F06 compound treatment 1013017.0 407000.0 0.86 976200.0 337000.0 0.77 1.1509 0.9982 3118755 ChemDiv3_001172 COc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F07 compound treatment 839002.0 233000.0 0.49 695669.0 56000.0 0.13 0.439 0.8614 1922655 ChemDiv3_001173 Cc1ccc(cc1)N2C(=O)/C(=C/C=C/c3ccccc3)/SC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F08 compound treatment 1024034.0 418000.0 0.89 1066618.0 427000.0 0.97 1.3128 0.999 1328915 ChemDiv3_001174 COc1cccc(c1)N2C(=O)CC(SCC(=O)Nc3ccc4ccccc4c3)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F09 compound treatment 1071880.0 466000.0 0.99 1137434.0 498000.0 1.13 1.4983 0.9977 1522826 ChemDiv3_001175 Cc1ccc2n(C)cc(C(=O)O)c(=O)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F10 compound treatment 1141002.0 535000.0 1.13 1140332.0 501000.0 1.14 1.6066 1.0 3118902 ChemDiv3_001176 O=C(COC(=O)c1cccs1)c2ccc3OCCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F11 compound treatment 1111272.0 505000.0 1.07 1191349.0 552000.0 1.25 1.6441 0.9969 3118903 ChemDiv3_001177 Cc1cc(C)c(C2=NON3N(C(=O)c4cccs4)c5ccccc5N32)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F12 compound treatment 1450921.0 845000.0 1.79 1340670.0 701000.0 1.59 2.3933 0.9983 1311807 ChemDiv3_001178 Cc1noc(n1)c2ccccc2OC(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F13 compound treatment 1240251.0 634000.0 1.34 1222982.0 583000.0 1.33 1.8883 1.0 3020393 ChemDiv3_001179 CCOC(=O)c1cc(no1)c2cc(OC)ccc2OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F14 compound treatment 1025075.0 419000.0 0.89 1179152.0 540000.0 1.23 1.4952 0.9874 1637396 ChemDiv3_001180 COc1nc(C)nc(NCC=C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F15 compound treatment 874359.0 268000.0 0.57 914580.0 275000.0 0.63 0.844 0.9989 3118904 ChemDiv3_001181 Cc1ccc(cc1)C2C(=C(Oc3ccccc23)c4cccs4)C=C5C(=O)NC(=O)NC5=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F16 compound treatment 930319.0 324000.0 0.69 965975.0 326000.0 0.74 1.0105 0.9993 1442359 ChemDiv3_001182 COc1ccc(OCC(O)Cn2nc(C)cc2C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F17 compound treatment 912865.0 307000.0 0.65 831148.0 192000.0 0.44 0.7676 0.981 3118905 ChemDiv3_001183 CN(C)c1ccc(N/C=C/2\N=C(OC2=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F18 compound treatment 1024475.0 418000.0 0.89 1147659.0 508000.0 1.16 1.4437 0.9915 1362058 ChemDiv3_001184 COc1cccc(CC(=O)Nn2c(C)nc3ccccc3c2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F19 compound treatment 920233.0 314000.0 0.67 931894.0 292000.0 0.66 0.9406 1.0 3118906 ChemDiv3_001185 C1CCc2c(C1)sc3ncn4nc(nc4c23)c5cccnc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F20 compound treatment 790398.0 184000.0 0.39 767278.0 128000.0 0.29 0.4813 0.9893 1616159 ChemDiv3_001186 Cc1ccc(CNC(=O)C2c3ccccc3Oc4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F21 compound treatment 749342.0 143000.0 0.3 884365.0 245000.0 0.56 0.608 0.9593 1782607 ChemDiv3_001187 CCC(CC(C)(C)O)c1n[nH]c(=S)n1CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F22 compound treatment 740131.0 134000.0 0.28 836373.0 197000.0 0.45 0.517 0.9759 3118907 ChemDiv3_001188 O=C(CSC1=NC(=O)C(C(=O)N1)c2ccccc2)NC3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F23 mock treatment 636668.0 30400.0 0.06 783333.0 144000.0 0.33 0.2767 0.8307 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 F24 mock treatment 408889.0 -197000.0 -0.42 530034.0 -110000.0 -0.25 -0.472 -0.9693 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G01 compound treatment 570526.0 -35700.0 -0.08 899128.0 260000.0 0.59 0.3637 0.6114 3020400 ChemDiv3_001189 C=CCn1c(n[nH]c1=S)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G02 compound treatment 975449.0 369000.0 0.78 980568.0 341000.0 0.78 1.1016 1.0 1285595 ChemDiv3_001190 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc-3c(CCc4ccccc34)s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G03 compound treatment 991844.0 386000.0 0.82 1087449.0 448000.0 1.02 1.298 0.9941 1230309 ChemDiv3_001191 C[N+]1(CCC2CC1)C(=C)C2(O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G04 compound treatment 885584.0 279000.0 0.59 858844.0 219000.0 0.5 0.7712 0.9963 3118908 ChemDiv3_001192 COc1ccc2c(C)cc(Sc3nnnn3c4ccccc4)nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G05 compound treatment 819449.0 213000.0 0.45 816410.0 177000.0 0.4 0.6038 0.9983 3020403 ChemDiv3_001193 Cc1ccc(/N=C\2/C(=O)Nc3ccccc23)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G06 compound treatment 556840.0 -49400.0 -0.1 676118.0 36500.0 0.08 -0.0154 -0.115 1391577 ChemDiv3_001194 COC(=O)C1=C(C)NC2=C(C1c3ccccc3OC(C)C)C(=O)CC(C2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G07 compound treatment 1141983.0 536000.0 1.14 1128574.0 489000.0 1.11 1.5892 0.9999 1779181 ChemDiv3_001195 Cc1cc(=O)[nH]c(SC(C(=O)O)c2ccccc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G08 compound treatment 341948.0 -264000.0 -0.56 322961.0 -317000.0 -0.72 -0.9052 -0.9923 1705952 ChemDiv3_001196 O=C(C(Sc1nc2ccccc2[nH]1)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G09 compound treatment 1204285.0 598000.0 1.27 1241302.0 602000.0 1.37 1.8638 0.9993 3020442 ChemDiv3_001197 COc1ccc(/C=N/N2C(=O)/C(=C/c3ccc(OC)cc3)/SC2=S)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G10 compound treatment 1512074.0 906000.0 1.92 1197923.0 558000.0 1.27 2.2554 0.9798 1503189 ChemDiv3_001198 CNC(=O)c1ccc2nc(N)sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G11 compound treatment 1236247.0 630000.0 1.34 1390404.0 751000.0 1.71 2.1514 0.9926 1316072 ChemDiv3_001199 O=S(=O)(N1CCCC1)c2cccc(c2)c3nnc(o3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G12 compound treatment 1515451.0 909000.0 1.93 1172972.0 533000.0 1.21 2.2204 0.975 3118909 ChemDiv3_001200 Cc1cc(/C=C/2\SC(=O)NC2=O)c(C)n1c3cc(C)cc(C)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G13 compound treatment 1392731.0 787000.0 1.67 1421469.0 782000.0 1.78 2.4359 0.9995 3020445 ChemDiv3_001201 CC(=C)Cn1c(SCC(=O)O)nnc1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G14 compound treatment 1608260.0 1000000.0 2.12 1399036.0 759000.0 1.73 2.7229 0.9947 3118910 ChemDiv3_001202 Cc1ccc(cc1)c2nnc(SC(=O)OCc3ccccc3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G15 compound treatment 1177602.0 571000.0 1.21 1367245.0 728000.0 1.65 2.0263 0.9883 3118911 ChemDiv3_001203 COc1ccc(cc1)n2cnc3cc(/N=C/c4nc5ccccc5n4C)ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G16 compound treatment 1064545.0 458000.0 0.97 1456327.0 817000.0 1.86 2.0 0.9544 3020449 ChemDiv3_001204 CN(/N=C/c1ccc(C)cc1)S(=O)(=O)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G17 compound treatment 1049342.0 443000.0 0.94 1239041.0 599000.0 1.36 1.6279 0.9835 3118912 ChemDiv3_001205 CCCCC(=O)/C=C/n1c(=S)oc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G18 compound treatment 187540.0 -419000.0 -0.89 116071.0 -524000.0 -1.19 -1.4693 -0.9896 3020450 ChemDiv3_001206 CNCCc1c(c2ccccc2)n(c3ccccc3)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G19 compound treatment 735912.0 130000.0 0.27 887203.0 248000.0 0.56 0.5924 0.9457 1598116 ChemDiv3_001207 CC(C)(C)c1ccccc1OCC(=O)Nc2cccc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G20 compound treatment 879154.0 273000.0 0.58 1027825.0 388000.0 0.88 1.0332 0.979 1411248 ChemDiv3_001208 CC(C)(C)OC(=O)C1=C(N)OC2=C(C(=O)CC(C)(C)C2)C31C(=O)Nc4ccccc43 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G21 compound treatment 915874.0 310000.0 0.66 1059000.0 419000.0 0.95 1.1384 0.9834 1864191 ChemDiv3_001209 CCC(Sc1n[nH]c(=O)[nH]c1=O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G22 compound treatment 860832.0 255000.0 0.54 1064890.0 425000.0 0.97 1.0653 0.9621 3020455 ChemDiv3_001210 O=C/1N(Cc2ccccc2)C(=S)S\C1=C/c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G23 mock treatment 708436.0 102000.0 0.22 910601.0 271000.0 0.62 0.5889 0.9017 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 G24 mock treatment 964894.0 359000.0 0.76 847269.0 208000.0 0.47 0.8715 0.9737 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H01 compound treatment 504737.0 -101000.0 -0.22 811375.0 172000.0 0.39 0.124 0.2781 3118913 ChemDiv3_001211 O=C(/C(=C/1\Nc2ccccc2S1)/C#N)c3ccc(cc3)C(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H02 compound treatment 843839.0 238000.0 0.5 1182419.0 543000.0 1.23 1.2288 0.9219 3020457 ChemDiv3_001212 FC(F)(F)c1cccc(c1)N2C(=O)CC(C3CCCO3)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H03 compound treatment 301838.0 -304000.0 -0.65 390016.0 -250000.0 -0.57 -0.8576 -0.9979 1133915 ChemDiv3_001213 CC1CCc2nc(NC(=O)c3ccc(Cc4ccccc4)cc3)sc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H04 compound treatment 912753.0 307000.0 0.65 986714.0 347000.0 0.79 1.0175 0.9953 1679724 ChemDiv3_001214 OC(=O)CCSc1nc2ccccc2n1C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H05 compound treatment 954590.0 348000.0 0.74 1044535.0 405000.0 0.92 1.1732 0.994 3118914 ChemDiv3_001215 COc1ccc(OC)c(N/C=C(\C#N)/c2nc(cs2)c3cc4ccccc4oc3=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H06 compound treatment 1125354.0 519000.0 1.1 1081570.0 442000.0 1.0 1.4887 0.999 3020524 ChemDiv3_001216 Clc1ccc(SCCc2nc3ccccc3o2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H07 compound treatment 1149098.0 543000.0 1.15 1254653.0 615000.0 1.4 1.8025 0.9953 1413360 ChemDiv3_001217 Clc1ccc(SCC2=NN(C(=O)C2)c3nc4ccccc4s3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H08 compound treatment 1209839.0 604000.0 1.28 1319305.0 680000.0 1.55 1.9975 0.9956 1533668 ChemDiv3_001218 Cc1ccc(SC2=NS(=O)(=O)c3ccccc23)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H09 compound treatment 1183874.0 578000.0 1.22 1408353.0 769000.0 1.75 2.1018 0.9849 3118915 ChemDiv3_001219 COc1ccc(OCCSc2nc3ccccc3s2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H10 compound treatment 1308622.0 702000.0 1.49 1495857.0 856000.0 1.95 2.4294 0.9912 1368307 ChemDiv3_001220 COc1ccc(cc1)C(=O)CSc2nc3cc(OC)ccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H11 compound treatment 1594204.0 988000.0 2.09 1691386.0 1050000.0 2.39 3.1719 0.9978 1480108 ChemDiv3_001221 COc1cc(cc(OC)c1OC)C(=O)NCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H12 compound treatment 1822127.0 1220000.0 2.58 1941703.0 1300000.0 2.96 3.916 0.9976 1571229 ChemDiv3_001222 COc1ccc(cc1)C(=O)CC(CC(=O)c2ccc(OC)cc2)C#Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H13 compound treatment 1457272.0 851000.0 1.8 1500821.0 861000.0 1.96 2.6602 0.9992 1449253 ChemDiv3_001223 CC(=O)Oc1ccc(cc1)N(C(=O)C)S(=O)(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H14 compound treatment 1348256.0 742000.0 1.57 1760250.0 1120000.0 2.55 2.9139 0.9731 3020527 ChemDiv3_001224 COc1nc(nc(C)c1Br)N(CC=C)C(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H15 compound treatment 1530882.0 925000.0 1.96 2185021.0 1550000.0 3.51 3.8705 0.962 1303506 ChemDiv3_001225 COc1ccc(CCn2c(C)nc(=O)c(c2C)c3ccccc3)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H16 compound treatment 1222665.0 616000.0 1.31 1982663.0 1340000.0 3.05 3.0832 0.9283 1333831 ChemDiv3_001226 NS(=O)(=O)c1ccc(cc1)N2C(=O)C3CC=CCC3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H17 compound treatment 1264703.0 658000.0 1.4 1285270.0 646000.0 1.47 2.0251 0.9997 3020529 ChemDiv3_001227 CCc1cc2c(=O)oc(nc2s1)c3ccc(Br)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H18 compound treatment 1196578.0 590000.0 1.25 1581241.0 942000.0 2.14 2.3987 0.9673 1332696 ChemDiv3_001228 CCC(C)NC(=O)Cn1cnc2n(C)c(=O)n(C)c(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H19 compound treatment 956586.0 350000.0 0.74 1214513.0 575000.0 1.31 1.4494 0.9641 1174891 ChemDiv3_001229 OC(=O)C1CC(=C(CC1C(=O)c2ccccc2)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H20 compound treatment 966366.0 360000.0 0.76 1087071.0 447000.0 1.02 1.2592 0.99 1219244 ChemDiv3_001230 CCCNC(=O)N(C)c1nncnc1C(=O)NC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H21 compound treatment 938596.0 332000.0 0.7 975207.0 336000.0 0.76 1.0377 0.9992 1493398 ChemDiv3_001231 O=C1N(CC2OCc3ccccc3CO2)C(=O)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H22 compound treatment 924283.0 318000.0 0.67 958225.0 319000.0 0.72 0.989 0.9994 1293274 ChemDiv3_001232 Nc1nc(CSc2nnc3c4ccccc4[nH]c3n2)cs1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H23 mock treatment 880833.0 275000.0 0.58 832181.0 193000.0 0.44 0.7212 0.9901 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 H24 mock treatment 543680.0 -62500.0 -0.13 476084.0 -164000.0 -0.37 -0.3567 -0.9035 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I01 compound treatment 586031.0 -20200.0 -0.04 906268.0 267000.0 0.61 0.3984 0.6555 3119049 ChemDiv3_001233 CCn1c(n[nH]c1=S)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I02 compound treatment 1019474.0 413000.0 0.88 1188249.0 549000.0 1.25 1.5015 0.9851 3020534 ChemDiv3_001234 Cc1nc(SCC(=O)O)c2c3CCCCc3sc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I03 compound treatment 1055888.0 450000.0 0.95 1224952.0 585000.0 1.33 1.6151 0.9866 1118354 ChemDiv3_001235 Cc1ccc(cc1)C(=O)Nc2ccc3OCCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I04 compound treatment 831316.0 225000.0 0.48 789873.0 150000.0 0.34 0.579 0.9866 1277083 ChemDiv3_001236 CCOC(=O)c1[nH]cnc1C(=O)Nc2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I05 compound treatment 1039829.0 434000.0 0.92 1012970.0 373000.0 0.85 1.2502 0.9992 3119050 ChemDiv3_001237 COc1ccc(/C=N/n2cnc3n(C)c(=O)n(\N=C\c4ccc(OC)cc4)c(=O)c23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I06 compound treatment 1251014.0 645000.0 1.37 1158273.0 519000.0 1.18 1.8004 0.9973 3020597 ChemDiv3_001238 COC(=O)Sc1nnc(o1)c2ccc(Br)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I07 compound treatment 1159135.0 553000.0 1.17 1354504.0 715000.0 1.63 1.9781 0.9871 3020599 ChemDiv3_001239 Cc1cc(=O)[nH]c(SCC(=O)N)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I08 compound treatment 1348440.0 742000.0 1.57 1226821.0 587000.0 1.34 2.0566 0.9967 3119051 ChemDiv3_001240 Cc1ccc(/N=C(\NC(=S)N)/c2ccccc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I09 compound treatment 1318467.0 712000.0 1.51 1194943.0 555000.0 1.26 1.9604 0.996 3020601 ChemDiv3_001241 CN1CCN(CC1)NC(=O)CCN2C(=O)/C(=C\c3ccccc3)/SC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I10 compound treatment 1473684.0 867000.0 1.84 1350541.0 711000.0 1.62 2.4433 0.9979 3119052 ChemDiv3_001242 CN(C)c1cc[n+](cc1)C(=O)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I11 compound treatment 1639405.0 1030000.0 2.19 1516139.0 877000.0 1.99 2.9579 0.9989 3119053 ChemDiv3_001243 COc1ccccc1NC(=O)c/2cc3ccccc3o\c2=N/c4ccccc4F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I12 compound treatment 1170290.0 564000.0 1.2 1216885.0 577000.0 1.31 1.7736 0.9989 1781772 ChemDiv3_001244 Cc1cc(/C=C(\C#N)/c2ccccc2)c(C)n1c3cc(C)cc(C)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I13 compound treatment 1466685.0 860000.0 1.82 1421539.0 782000.0 1.78 2.5469 0.9999 1709347 ChemDiv3_001245 COc1ccc(cc1OC)c2nnc(S)n2c3ccccc3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I14 compound treatment 700606.0 94400.0 0.2 664172.0 24500.0 0.06 0.1809 0.8711 1417740 ChemDiv3_001246 OC(COc1cccc2cccnc12)Cn3c4ccccc4c5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I15 compound treatment 1205194.0 599000.0 1.27 1557676.0 918000.0 2.09 2.3738 0.9716 1639763 ChemDiv3_001247 CC(C)(C)c1ccc(Cn2c(=N)n(CC(=O)O)c3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I16 compound treatment 1180675.0 574000.0 1.22 1387745.0 748000.0 1.7 2.0638 0.9866 3119054 ChemDiv3_001248 COc1ccc(CC/N=C/2\SCC(=O)N2Cc3ccccc3)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I17 compound treatment 1127446.0 521000.0 1.1 1442427.0 803000.0 1.83 2.0719 0.9711 3020607 ChemDiv3_001249 Oc1ccccc1/C=N/N2C(=O)C3C4CC(C=C4)C3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I18 compound treatment 1178802.0 573000.0 1.21 1514954.0 875000.0 1.99 2.2655 0.9719 1913826 ChemDiv3_001250 COc1ccc(cc1)n2ccc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I19 compound treatment 939134.0 333000.0 0.71 1367904.0 728000.0 1.66 1.6699 0.9277 3119055 ChemDiv3_001251 CCN1C(=O)/C(=C/2\SC(=S)N(C2=O)c3cccc(Cl)c3)/c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I20 compound treatment 948506.0 342000.0 0.73 1156499.0 517000.0 1.18 1.344 0.9732 1707679 ChemDiv3_001252 Cc1ccc(Oc2ccccc2)c(NC(=O)c3ccccc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I21 compound treatment 882866.0 277000.0 0.59 1130065.0 490000.0 1.12 1.2031 0.955 1775109 ChemDiv3_001253 CC(C)n1c(=S)[nH]c2n(C)c(=O)[nH]c(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I22 compound treatment 129973.0 -476000.0 -1.01 195047.0 -445000.0 -1.01 -1.4286 -1.0 3020611 ChemDiv3_001254 Oc1ccc(CN2CCCC2)c3cccnc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I23 mock treatment 816036.0 210000.0 0.44 1225930.0 586000.0 1.33 1.2571 0.8946 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 I24 mock treatment 625550.0 19300.0 0.04 548515.0 -91100.0 -0.21 -0.1175 -0.5565 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J01 compound treatment 567123.0 -39100.0 -0.08 742835.0 103000.0 0.23 0.1073 0.4312 3119056 ChemDiv3_001255 CN1/C(=C(\C#N)/C(=O)c2ccc(F)cc2)/Nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J02 compound treatment 906767.0 301000.0 0.64 1199327.0 560000.0 1.27 1.3503 0.9489 3020669 ChemDiv3_001256 COc1ccc(Br)cc1/C=C/C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J03 compound treatment 914158.0 308000.0 0.65 1086317.0 447000.0 1.02 1.1797 0.9772 3119057 ChemDiv3_001257 CC1=C(C(c2ccccc2)n3c(=O)/c(=C/c4cccs4)/sc3=N1)C(=O)Nc5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J04 compound treatment 935599.0 329000.0 0.7 1069926.0 430000.0 0.98 1.1855 0.9863 3020672 ChemDiv3_001258 Fc1ccccc1OCCSc2nc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J05 compound treatment 1080992.0 475000.0 1.01 1039083.0 399000.0 0.91 1.3539 0.9987 3119058 ChemDiv3_001259 FC(F)(F)c1cccc(N/C=C(/C#N)\c2nc(cs2)c3ccc4OCOc4c3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J06 compound treatment 1204214.0 598000.0 1.27 1027596.0 388000.0 0.88 1.5201 0.9843 3020674 ChemDiv3_001260 O=C/1N\C(=N/S(=O)(=O)c2ccccc2)\S\C1=C\c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J07 compound treatment 1123196.0 517000.0 1.1 1169603.0 530000.0 1.2 1.627 0.9989 3119059 ChemDiv3_001261 CC1(C)CC(=O)C(=CNC2CCCC2)C(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J08 compound treatment 1211303.0 605000.0 1.28 1214191.0 575000.0 1.31 1.8307 1.0 1223136 ChemDiv3_001262 OC(=O)CCC(=O)Nc1cccc(c1)c2nc3ccccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J09 compound treatment 1093247.0 487000.0 1.03 1214737.0 575000.0 1.31 1.6546 0.9932 1160808 ChemDiv3_001263 CC(=O)Oc1ccccc1C(=O)N2CCCc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J10 compound treatment 917527.0 311000.0 0.66 795267.0 156000.0 0.35 0.7169 0.9573 1127019 ChemDiv3_001264 N=c1n(CC(=O)c2ccco2)c3ccccc3n1Cc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J11 compound treatment 1660866.0 1050000.0 2.24 1368918.0 729000.0 1.66 2.7534 0.9892 3020678 ChemDiv3_001265 O=C(CSc1nc2ccccc2s1)OCN3C(=O)c4ccccc4C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J12 compound treatment 1878221.0 1270000.0 2.7 1638702.0 999000.0 2.27 3.5129 0.9964 3119060 ChemDiv3_001266 C1C(=CC(=NN=C1c2cccs2)c3cccs3)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J13 compound treatment 1815856.0 1210000.0 2.56 1913914.0 1270000.0 2.9 3.8619 0.9981 1124209 ChemDiv3_001267 O=C(CCN1C(=O)c2ccccc2C1=O)Oc3ccc4c5CCCc5c(=O)oc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J14 compound treatment 1566267.0 960000.0 2.04 1719430.0 1080000.0 2.45 3.1751 0.9957 3020681 ChemDiv3_001268 CCNc1nc(NCC)nc(OCCOC(=O)C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J15 compound treatment 1315036.0 709000.0 1.5 1196540.0 557000.0 1.27 1.9579 0.9964 1222243 ChemDiv3_001269 COc1ccc(cc1OC)C2=CC(c3ccccc3)c4ccccc4O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J16 compound treatment 1280250.0 674000.0 1.43 1043387.0 404000.0 0.92 1.6595 0.9771 1443019 ChemDiv3_001270 O=C(Nc1ccc(cc1)N2CCCCC2)c3ccncc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J17 compound treatment 1112186.0 506000.0 1.07 1045225.0 406000.0 0.92 1.4105 0.9972 1518842 ChemDiv3_001271 CCOC(=O)c1cc2c3c4CCCCc4oc3cc(I)c2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J18 compound treatment 1073925.0 468000.0 0.99 1123565.0 484000.0 1.1 1.4791 0.9987 3020684 ChemDiv3_001272 FC(F)(F)c1ccccc1NC(=O)C2c3ccccc3Oc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J19 compound treatment 822482.0 216000.0 0.46 820618.0 181000.0 0.41 0.6152 0.9985 3119061 ChemDiv3_001273 Fc1ccc(/N=C/2\SC(CC(=O)N2CCc3ccccc3)C(=O)NCCc4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J20 compound treatment 1018272.0 412000.0 0.87 972766.0 333000.0 0.76 1.1532 0.9975 1484388 ChemDiv3_001274 Cc1cccc(NC(=O)c2ccc(C)c(c2)S(=O)(=O)N3CCCC3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J21 compound treatment 867091.0 261000.0 0.55 908439.0 269000.0 0.61 0.8232 0.9988 3020364 ChemDiv3_001275 CN(C)c1ccc(/C=C(\C#N)/C(=C(C#N)C#N)N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J22 compound treatment 869339.0 263000.0 0.56 903449.0 264000.0 0.6 0.8186 0.9993 1381241 ChemDiv3_001276 Nc1ccccc1Nc2c(N)c(=O)oc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J23 mock treatment 857024.0 251000.0 0.53 960110.0 320000.0 0.73 0.8912 0.988 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 J24 mock treatment 712835.0 107000.0 0.23 567523.0 -72100.0 -0.16 0.0439 0.1572 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K01 compound treatment 349084.0 -257000.0 -0.55 481455.0 -158000.0 -0.36 -0.6397 -0.9796 3020366 ChemDiv3_001277 Oc1ccccc1N2C(=O)/C(=C/c3ccc(Br)cc3)/C=C2c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K02 compound treatment 826440.0 220000.0 0.47 985873.0 346000.0 0.79 0.8868 0.9689 3119062 ChemDiv3_001278 CCOC(=O)c1cnn(c1N)c2nc(C)cc(C)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K03 compound treatment 909634.0 303000.0 0.64 959481.0 320000.0 0.73 0.969 0.9981 1164643 ChemDiv3_001279 Cc1nn(c(C)c1Sc2n[nH]c(=O)[nH]c2=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K04 compound treatment 890551.0 284000.0 0.6 926629.0 287000.0 0.65 0.8876 0.9992 3119063 ChemDiv3_001280 Cc1ccc2nc(Nc3ccccc3)nc(c4ccccc4)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K05 compound treatment 871712.0 265000.0 0.56 959556.0 320000.0 0.73 0.9123 0.992 1371214 ChemDiv3_001281 CCOC(=O)c1cnn(c1NC(=O)c2ccccc2F)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K06 compound treatment 994526.0 388000.0 0.82 1001698.0 362000.0 0.82 1.1642 1.0 3020371 ChemDiv3_001282 COC(=O)C(C)Sc1nnc(o1)c2ccc(Br)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K07 compound treatment 756732.0 151000.0 0.32 822290.0 183000.0 0.42 0.5193 0.9915 3119064 ChemDiv3_001283 Cc1nc(cs1)c2c(oc3cc(O)ccc3c2=O)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K08 compound treatment 998663.0 392000.0 0.83 931924.0 292000.0 0.66 1.0582 0.9938 3020374 ChemDiv3_001284 Brc1ccc(cc1)n2c(nc(=S)c3CCCCc32)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K09 compound treatment 1028224.0 422000.0 0.89 1013425.0 374000.0 0.85 1.2335 0.9997 3119065 ChemDiv3_001285 CSc1nnc(c(=O)n1/N=C/c2c(O)ccc3ccccc23)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K10 compound treatment 1115910.0 510000.0 1.08 1036782.0 397000.0 0.9 1.4025 0.996 3020376 ChemDiv3_001286 CCN(CC)C(=O)[n+]1ccc(OC)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K11 compound treatment 1280546.0 674000.0 1.43 1064000.0 424000.0 0.96 1.6931 0.9817 1516068 ChemDiv3_001287 CCCOC(=O)C1=C(C)N(CC)C(=O)NC1c2ccccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K12 compound treatment 1433895.0 828000.0 1.75 1381719.0 742000.0 1.69 2.4337 0.9998 3119198 ChemDiv3_001288 CCOC(=O)c1ccc(cc1)n2c(C)cc(C=C3C(=O)NC(=S)NC3=O)c2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K13 compound treatment 1140117.0 534000.0 1.13 1136139.0 497000.0 1.13 1.5985 1.0 3119199 ChemDiv3_001289 Cc1ccc(/C=N/c2ccc(Br)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K14 compound treatment 1107902.0 502000.0 1.06 1207173.0 568000.0 1.29 1.6644 0.9954 3020408 ChemDiv3_001290 COC(=O)C1=C(C)N=c2s/c(=C/c3ccc(OC)cc3)/c(=O)n2C1c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K15 compound treatment 450754.0 -155000.0 -0.33 454767.0 -185000.0 -0.42 -0.5302 -0.9928 1548396 ChemDiv3_001291 CC(C)(C)C(O)Cn1c(=N)n(CCN2CCCCC2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K16 compound treatment 925179.0 319000.0 0.68 975496.0 336000.0 0.76 1.0181 0.9982 3020412 ChemDiv3_001292 CC1=NN(C(=O)c2ccc(Cl)cc2)C(C)(C)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K17 compound treatment 697090.0 90900.0 0.19 742762.0 103000.0 0.23 0.302 0.9952 3119200 ChemDiv3_001293 Brc1cccc(c1)C2CC(=O)c3c(N2)ccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K18 compound treatment 857345.0 251000.0 0.53 959686.0 320000.0 0.73 0.891 0.9882 1559376 ChemDiv3_001294 CCCCN1CCc2c([nH]c3c(C)cccc23)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K19 compound treatment 731283.0 125000.0 0.27 946428.0 307000.0 0.7 0.6807 0.9122 3119201 ChemDiv3_001295 CCN1C(=O)/C(=C/2\SC(=S)N(C2=O)c3ccc(OC)cc3)/c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K20 compound treatment 748662.0 142000.0 0.3 943725.0 304000.0 0.69 0.7024 0.931 1381466 ChemDiv3_001296 COc1ccc(cc1)n2c(nc3cc4OCOc4cc23)c5ccc(Br)cc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K21 compound treatment 781042.0 175000.0 0.37 885775.0 246000.0 0.56 0.6578 0.98 1048818 ChemDiv3_001297 O=C(Oc1ccccc1)C(c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K22 compound treatment 623179.0 17000.0 0.04 895665.0 256000.0 0.58 0.437 0.7493 1302006 ChemDiv3_001298 CCc1nc(C)cn1S(=O)(=O)c2cc(OC)ccc2OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K23 mock treatment 668214.0 62000.0 0.13 861804.0 222000.0 0.51 0.4501 0.8624 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 K24 mock treatment 540769.0 -65500.0 -0.14 606552.0 -33100.0 -0.08 -0.1513 -0.9586 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L01 compound treatment 525664.0 -80600.0 -0.17 682226.0 42600.0 0.1 -0.0523 -0.2662 3119202 ChemDiv3_001299 CN1/C(=C(\C#N)/C(=O)c2ccccc2NS(=O)(=O)c3ccc(C)cc3)/Nc4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L02 compound treatment 789896.0 184000.0 0.39 838252.0 199000.0 0.45 0.5947 0.9973 1913204 ChemDiv3_001300 OC(=O)/C=C/c1ccc(o1)c2ccc(Br)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L03 compound treatment 946017.0 340000.0 0.72 851559.0 212000.0 0.48 0.8501 0.9809 1267306 ChemDiv3_001301 Clc1ccc(OCC(=O)NCc2n[nH]c(=S)n2c3cccc(Cl)c3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L04 compound treatment 805356.0 199000.0 0.42 747516.0 108000.0 0.25 0.472 0.9666 1204085 ChemDiv3_001302 O=C1CC(CC(=C1)NC2CCCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L05 compound treatment 1051323.0 445000.0 0.94 831318.0 192000.0 0.44 0.9754 0.9384 3119203 ChemDiv3_001303 Fc1ccccc1N/C=C(\C#N)/c2nc(cs2)c3cc4ccccc4oc3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L06 compound treatment 702629.0 96400.0 0.2 965157.0 326000.0 0.74 0.6679 0.8698 3119204 ChemDiv3_001304 O=C/1N\C(=N\S(=O)(=O)c2ccccc2)\S\C1=C/3\C(=O)Nc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L07 compound treatment 553506.0 -52700.0 -0.11 825455.0 186000.0 0.42 0.2197 0.5028 3020464 ChemDiv3_001305 CC1(C)CC(=O)C(=CNCc2ccc(F)cc2)C(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L08 compound treatment 1015635.0 409000.0 0.87 827938.0 188000.0 0.43 0.9165 0.947 1301856 ChemDiv3_001306 OC(=O)c1ccc(CN2C(=O)c3ccc(cc3C2=O)C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L09 compound treatment 981201.0 375000.0 0.79 1011900.0 372000.0 0.85 1.1606 0.9995 1358651 ChemDiv3_001307 OC1(N(CCc2ccccc2)C(=O)c3ccccc31)c4ncc[nH]4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L10 compound treatment 306166.0 -300000.0 -0.64 359318.0 -280000.0 -0.64 -0.9004 -1.0 3119205 ChemDiv3_001308 O=C(CN1C2=NCCCN2c3ccccc13)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L11 compound treatment 1165395.0 559000.0 1.19 947188.0 308000.0 0.7 1.3327 0.9683 1633574 ChemDiv3_001309 CC1=C(C)CC(C(C1)C(=O)O)C(=O)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L12 compound treatment 1510751.0 905000.0 1.92 1359953.0 720000.0 1.64 2.5139 0.9969 1136469 ChemDiv3_001310 Sc1nc2sc3CCCc3c2c(=O)n1Cc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L13 compound treatment 1523038.0 917000.0 1.94 1528555.0 889000.0 2.02 2.8034 0.9998 1155907 ChemDiv3_001311 CC(C)CC(N1C(=O)c2ccccc2C1=O)C(=O)Oc3ccc4c5CCCc5c(=O)oc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L14 compound treatment 1102888.0 497000.0 1.05 1323774.0 684000.0 1.56 1.8444 0.9819 1677666 ChemDiv3_001312 CCN(c1nc(C)cc(OC)n1)S(=O)(=O)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L15 compound treatment 1023288.0 417000.0 0.88 1003882.0 364000.0 0.83 1.2108 0.9995 3119206 ChemDiv3_001313 COc1cc2cc(C)nc(Cc3cccc4ccccc34)c2cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L16 compound treatment 922315.0 316000.0 0.67 888944.0 249000.0 0.57 0.8746 0.9965 3020469 ChemDiv3_001314 CCCOC(=O)Nc1cccc(c1)C(=O)OCCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L17 compound treatment 842875.0 237000.0 0.5 931617.0 292000.0 0.66 0.8242 0.9905 3119207 ChemDiv3_001315 Cc1ccc(cc1)c2csc(NC(=O)/C=C/c3ccco3)c2C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L18 compound treatment 970397.0 364000.0 0.77 975081.0 335000.0 0.76 1.0852 1.0 1128259 ChemDiv3_001316 CCOc1ccc(NC(=O)C2c3ccccc3Oc4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L19 compound treatment 818030.0 212000.0 0.45 810930.0 171000.0 0.39 0.5929 0.9975 3119208 ChemDiv3_001317 CN/1C(=O)CC(S\C1=N\c2ccc(I)cc2)C(=O)NCCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L20 compound treatment 839121.0 233000.0 0.49 808979.0 169000.0 0.39 0.6214 0.9924 1229602 ChemDiv3_001318 Cc1ccc(cc1C(=O)Oc2cccc3cccnc23)S(=O)(=O)N4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L21 compound treatment 763624.0 157000.0 0.33 872807.0 233000.0 0.53 0.6108 0.9751 1681096 ChemDiv3_001319 COc1cccc(C(O)c2nccn2C)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L22 compound treatment 785050.0 179000.0 0.38 955345.0 316000.0 0.72 0.7756 0.9555 1212845 ChemDiv3_001320 CCn1c(C)nc2c(=O)oc3ccccc3c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L23 mock treatment 659174.0 52900.0 0.11 940071.0 300000.0 0.68 0.5624 0.8124 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 L24 mock treatment 492881.0 -113000.0 -0.24 479938.0 -160000.0 -0.36 -0.4266 -0.9799 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M01 compound treatment 563256.0 -43000.0 -0.09 735624.0 96000.0 0.22 0.0899 0.3802 3119209 ChemDiv3_001321 O=C/1N(C2CCCCC2)C(=S)S\C1=C/c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M02 compound treatment 926271.0 320000.0 0.68 902820.0 263000.0 0.6 0.9029 0.998 3119210 ChemDiv3_001322 COC(=O)CN1C(c2ccccc2)c3cc(C)ccc3N=C1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M03 compound treatment 888540.0 282000.0 0.6 912229.0 273000.0 0.62 0.8615 0.9998 3020541 ChemDiv3_001323 Clc1ccc(/C=C/2\SC(=O)N(Cc3ccccc3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M04 compound treatment 889103.0 283000.0 0.6 971878.0 332000.0 0.76 0.9582 0.9935 3119211 ChemDiv3_001324 NNc1nc(c2ccccc2)c3cc(Cl)ccc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M05 compound treatment 756767.0 151000.0 0.32 853577.0 214000.0 0.49 0.5696 0.9791 3020543 ChemDiv3_001325 CC1=Nc2ccc(Br)cc2C(N1CC(=O)NN)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M06 compound treatment 1068741.0 463000.0 0.98 1053169.0 414000.0 0.94 1.3582 0.9998 1584812 ChemDiv3_001326 CC(C(Cc1cc(C)cc(C)c1)C(=O)O)C(=O)NCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M07 compound treatment 984764.0 379000.0 0.8 1146750.0 507000.0 1.15 1.3827 0.9843 1680758 ChemDiv3_001327 CCOC(=O)C(C)Oc1ccc2c(=O)c(coc2c1)c3csc(C)n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M08 compound treatment 1055504.0 449000.0 0.95 1189673.0 550000.0 1.25 1.5578 0.991 3020614 ChemDiv3_001328 Cn1/c(=N/C(=O)c2ccc(F)cc2)/sc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M09 compound treatment 931870.0 326000.0 0.69 1093331.0 454000.0 1.03 1.2176 0.9809 1701030 ChemDiv3_001329 C1OC(OCC12COC(OC2)c3cccnc3)c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M10 compound treatment 1048212.0 442000.0 0.94 1033756.0 394000.0 0.9 1.2962 0.9998 1243322 ChemDiv3_001330 COC(=O)c1cc(ccc1Cl)N2C(=O)C3C4OC(C)(C=C4)C3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M11 compound treatment 930315.0 324000.0 0.69 970890.0 331000.0 0.75 1.0184 0.9989 3119212 ChemDiv3_001331 CC(=O)N/C(=C\c1ccccc1)/C(=O)Nc2cccc(C#N)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M12 compound treatment 1078818.0 473000.0 1.0 1207133.0 568000.0 1.29 1.6208 0.9922 1297939 ChemDiv3_001332 OC(=O)c1cc(NC(=O)Cc2cccs2)cc(c1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M13 compound treatment 996656.0 390000.0 0.83 1032613.0 393000.0 0.89 1.2171 0.9993 1112646 ChemDiv3_001333 Clc1ccc(cc1)C(=O)Nc2cccc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M14 compound treatment 915932.0 310000.0 0.66 912916.0 273000.0 0.62 0.9036 0.9996 1527595 ChemDiv3_001334 O=C1CSC(N1C2CCCCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M15 compound treatment 143898.0 -462000.0 -0.98 150071.0 -490000.0 -1.11 -1.4801 -0.998 1359293 ChemDiv3_001335 CCCn1c(=N)n(CC(O)c2ccccc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M16 compound treatment 565977.0 -40200.0 -0.09 585966.0 -53700.0 -0.12 -0.1466 -0.9847 1703127 ChemDiv3_001336 Cc1nn(C(CC(=O)O)C(=O)O)c(C)c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M17 compound treatment 216919.0 -389000.0 -0.83 220328.0 -419000.0 -0.95 -1.2577 -0.9974 3119213 ChemDiv3_001337 Cc1ccccc1C2CC(=O)c3c(N2)ccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M18 compound treatment 1027827.0 422000.0 0.89 1078238.0 439000.0 1.0 1.3371 0.9985 3020623 ChemDiv3_001338 CCCCN1C(=O)/C(=C\2/Sc3ccc(OC)cc3N2C)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M19 compound treatment 747257.0 141000.0 0.3 640112.0 488.0 0.0 0.2122 0.7097 1127450 ChemDiv3_001339 COC(=O)c1c(NC(=O)c2c(C)onc2c3ccccc3Cl)sc4CCCCc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M20 compound treatment 808547.0 202000.0 0.43 805235.0 166000.0 0.38 0.5695 0.9979 1635195 ChemDiv3_001340 COc1ccc(NC(=O)Nc2c(SC)nsc2SC)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M21 compound treatment 736414.0 130000.0 0.28 852211.0 213000.0 0.48 0.5369 0.9647 3119214 ChemDiv3_001341 Nc1ccc(cc1)C(=O)OCCCc2nc3cc4ccccc4cc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M22 compound treatment 810966.0 205000.0 0.43 894440.0 255000.0 0.58 0.7166 0.9899 1632781 ChemDiv3_001342 Cc1ccc(c(C)c1)S(=O)(=O)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M23 mock treatment 667876.0 61700.0 0.13 813915.0 174000.0 0.4 0.3726 0.893 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 M24 mock treatment 492071.0 -114000.0 -0.24 589786.0 -49800.0 -0.11 -0.2512 -0.9402 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N01 compound treatment 522232.0 -84000.0 -0.18 522187.0 -117000.0 -0.27 -0.3147 -0.9806 1638529 ChemDiv3_001343 COC(=O)C1=C(CCS1)NC(=O)c2ccccc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N02 compound treatment 731369.0 125000.0 0.27 715272.0 75600.0 0.17 0.3092 0.978 1175429 ChemDiv3_001344 Cc1c(oc2ccccc12)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N03 compound treatment 807832.0 202000.0 0.43 617709.0 -21900.0 -0.05 0.267 0.6205 3119343 ChemDiv3_001345 CCOc1cccc(c1)S(=O)(=O)N=C2C=C(C(=O)C(=C2)C(C)(C)C)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N04 compound treatment 908156.0 302000.0 0.64 788409.0 149000.0 0.34 0.6918 0.9556 3020687 ChemDiv3_001346 N/C(=N\O)/CSc1nc2ccccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N05 compound treatment 1027732.0 422000.0 0.89 699401.0 59800.0 0.14 0.728 0.8054 1691239 ChemDiv3_001347 CCOC(=O)C1CCCN(Cc2ccccc2)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N06 compound treatment 928711.0 322000.0 0.68 816410.0 177000.0 0.4 0.7676 0.9679 1225871 ChemDiv3_001348 COc1ccc(OCC(=O)N2CCN(CC2)S(=O)(=O)c3ccc(OC)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N07 compound treatment 905134.0 299000.0 0.63 776779.0 137000.0 0.31 0.6686 0.9467 3119344 ChemDiv3_001349 CCOC(=O)c1sc2nc[nH]c(=O)c2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N08 compound treatment 1047566.0 441000.0 0.94 682193.0 42600.0 0.1 0.73 0.7761 1528087 ChemDiv3_001350 Cc1cc(C)nc(Nc2ncc(O)n2c3ccc(Cl)c(Cl)c3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N09 compound treatment 1030002.0 424000.0 0.9 766016.0 126000.0 0.29 0.8385 0.8889 1141041 ChemDiv3_001351 OC(=O)CCP(=O)(O)CN1CCCCCC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N10 compound treatment 153129.0 -453000.0 -0.96 159037.0 -481000.0 -1.09 -1.4518 -0.9979 1699621 ChemDiv3_001352 Clc1ccc(cc1Cl)C(=O)Cn2c(=N)n(Cc3ccccc3)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N11 compound treatment 1021874.0 416000.0 0.88 650141.0 10500.0 0.02 0.64 0.726 3020690 ChemDiv3_001353 CCC1C(=O)NC(=NC1=O)SCC(=O)Nc2ccc(Br)cn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N12 compound treatment 1046640.0 440000.0 0.93 897491.0 258000.0 0.59 1.0748 0.9749 1287141 ChemDiv3_001354 CC(=O)Nc1ccc(cc1)C(=O)CSc2nc(C)cc(O)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N13 compound treatment 852084.0 246000.0 0.52 870146.0 231000.0 0.52 0.7391 1.0 1716124 ChemDiv3_001355 Cc1cc(OC(=O)C2COc3ccccc3O2)cc(C)c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N14 compound treatment 1012922.0 407000.0 0.86 871907.0 232000.0 0.53 0.9831 0.9723 3119345 ChemDiv3_001356 CCN1OCN(C1=N)c2nc(nc(n2)N(C)C)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N15 compound treatment 826437.0 220000.0 0.47 835094.0 195000.0 0.44 0.6444 0.9997 3119346 ChemDiv3_001357 COc1ccc(cc1)c2cc3cc(OC)c(OC)cc3c(Cc4ccccc4)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N16 compound treatment 844675.0 238000.0 0.51 729055.0 89400.0 0.2 0.5012 0.9199 1442772 ChemDiv3_001358 CCOC(=O)c1c[nH]c2c(C)c(Cl)ccc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N17 compound treatment 883747.0 278000.0 0.59 927511.0 288000.0 0.65 0.8788 0.9986 3119347 ChemDiv3_001359 Cc1cc(C)c2cccc(NC(=S)NC(=O)/C=C/c3ccccc3)c2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N18 compound treatment 766822.0 161000.0 0.34 833931.0 194000.0 0.44 0.5531 0.9917 1476763 ChemDiv3_001360 CC1CC(C)CN(C1)C(=O)C2c3ccccc3Oc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N19 compound treatment 888901.0 283000.0 0.6 991499.0 352000.0 0.8 0.9894 0.9899 1211865 ChemDiv3_001361 COc1ccc(cc1)N2C(=O)CC(SCC(=O)O)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N20 compound treatment 753545.0 147000.0 0.31 660376.0 20800.0 0.05 0.2542 0.8048 1518987 ChemDiv3_001362 O=C(N1CCCc2ccccc12)c3cccc(c3)S(=O)(=O)NC4CCCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N21 compound treatment 786773.0 181000.0 0.38 936191.0 297000.0 0.67 0.7474 0.964 1331290 ChemDiv3_001363 CC1=C(C(NC(=O)N1)c2ccccc2)C(=O)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N22 compound treatment 759151.0 153000.0 0.32 860286.0 221000.0 0.5 0.584 0.9777 1486835 ChemDiv3_001364 Cc1nc2c(=O)oc3ccccc3c2n1c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N23 mock treatment 728336.0 122000.0 0.26 826507.0 187000.0 0.42 0.4835 0.9718 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 N24 mock treatment 571571.0 -34700.0 -0.07 393017.0 -247000.0 -0.56 -0.4484 -0.793 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O01 compound treatment 469419.0 -137000.0 -0.29 557278.0 -82300.0 -0.19 -0.3375 -0.9776 1423808 ChemDiv3_001365 CCOc1ccc(cc1Br)C(=O)Nc2ccc(NC(=O)c3ccccc3)c(C)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O02 compound treatment 875954.0 270000.0 0.57 783705.0 144000.0 0.33 0.636 0.965 3119348 ChemDiv3_001366 CCN1C(=O)c2cccc3c(NC(=S)NC(=O)c4ccccc4)ccc1c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O03 compound treatment 1181652.0 575000.0 1.22 1109096.0 469000.0 1.07 1.6173 0.9978 3020430 ChemDiv3_001367 Cc1cccc(NC(=O)CCN2C(=O)/C(=C\c3ccccc3)/SC2=S)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O04 compound treatment 1084904.0 479000.0 1.01 969925.0 330000.0 0.75 1.2486 0.989 1324540 ChemDiv3_001368 CCOc1ccc(NC(=O)NC2(CC3CC4CC(C3)C2)C4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O05 compound treatment 1114233.0 508000.0 1.08 1091742.0 452000.0 1.03 1.4884 0.9997 1278554 ChemDiv3_001369 Clc1cccc(c1)C(=O)NCC(=O)Nc2ccc(Br)cc2C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O06 compound treatment 1108995.0 503000.0 1.07 1170623.0 531000.0 1.21 1.6073 0.9981 1711492 ChemDiv3_001370 CN1N=C(C(NC(=O)C)C1=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O07 compound treatment 1011581.0 405000.0 0.86 1059372.0 420000.0 0.95 1.2824 0.9986 1278126 ChemDiv3_001371 CC(C)Oc1ccc2c(=O)c(c(C)oc2c1)c3ccc4OCCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O08 compound treatment 1082834.0 477000.0 1.01 1054404.0 415000.0 0.94 1.3813 0.9994 3021156 ChemDiv3_001372 N(=c/1\scc(c2cccs2)n1c3ccccc3)\c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O09 compound treatment 1143688.0 537000.0 1.14 1247755.0 608000.0 1.38 1.7833 0.9954 3021157 ChemDiv3_001373 FC(F)(F)c1ccccc1/C=C/2\N=C(OC2=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O10 compound treatment 1146242.0 540000.0 1.14 1183100.0 543000.0 1.24 1.6832 0.9993 3021158 ChemDiv3_001374 COc1ccccc1NC(=O)/C=C\c2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O11 compound treatment 986740.0 381000.0 0.81 904578.0 265000.0 0.6 0.9964 0.9897 3119349 ChemDiv3_001375 CCCCn1c(Cc2ccccc2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O12 compound treatment 1260462.0 654000.0 1.39 1094762.0 455000.0 1.03 1.7124 0.9896 1533954 ChemDiv3_001376 OC(=O)c1cc(NC(=O)c2cccs2)cc(c1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O13 compound treatment 1145235.0 539000.0 1.14 1129576.0 490000.0 1.11 1.5957 0.9999 1377349 ChemDiv3_001377 Brc1ccc2oc(=O)c(cc2c1)C(=O)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O14 compound treatment 1148119.0 542000.0 1.15 1239558.0 600000.0 1.36 1.7768 0.9964 3119350 ChemDiv3_001378 CCOC(=O)CC/1=NN(C(=O)\C1=C/c2cc(OC)c(OC)cc2OC)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O15 compound treatment 1054229.0 448000.0 0.95 1104183.0 465000.0 1.06 1.4184 0.9986 3021159 ChemDiv3_001379 CCn1c(/C=N/c2ccccc2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O16 compound treatment 331328.0 -275000.0 -0.58 354041.0 -286000.0 -0.65 -0.8712 -0.9985 1912932 ChemDiv3_001380 CCOC(=O)C1CNN=C1C(=O)OCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O17 compound treatment 1102912.0 497000.0 1.05 1209050.0 569000.0 1.29 1.66 0.9947 1144944 ChemDiv3_001381 CCOC(=O)c1ccc2nc(ccc2c1)C3(CC4CC5CC(C4)C3)C5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O18 compound treatment 938567.0 332000.0 0.7 1061219.0 422000.0 0.96 1.176 0.9885 3021160 ChemDiv3_001382 CCN1/C(=C\C(=S)CC)/Sc2ccc(Cl)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O19 compound treatment 1007195.0 401000.0 0.85 1000877.0 361000.0 0.82 1.1818 0.9999 1434944 ChemDiv3_001383 Brc1ccc(OCC(=O)NCC2CCCO2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O20 compound treatment 974593.0 368000.0 0.78 909912.0 270000.0 0.61 0.9867 0.993 1002861 ChemDiv3_001384 CC(Oc1ccccc1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O21 compound treatment 802060.0 196000.0 0.42 874062.0 234000.0 0.53 0.6705 0.9924 3119351 ChemDiv3_001385 O=C(Nc1cc2c(ccc3ccccc32)oc1=O)/C=C/c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O22 compound treatment 809791.0 204000.0 0.43 832520.0 193000.0 0.44 0.6153 1.0 3021161 ChemDiv3_001386 CCOC(=O)/C=C(\C)/Nc1ccc(Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O23 mock treatment 675587.0 69400.0 0.15 814607.0 175000.0 0.4 0.3853 0.9084 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 O24 mock treatment 414944.0 -191000.0 -0.41 464850.0 -175000.0 -0.4 -0.5677 -0.9999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P01 compound treatment 424850.0 -181000.0 -0.38 357043.0 -283000.0 -0.64 -0.7262 -0.9699 1607061 ChemDiv3_001387 COC(=O)C1=C(CCS1)NC(=O)c2cccc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P02 compound treatment 606366.0 141.0 0.0 385999.0 -254000.0 -0.58 -0.4075 -0.7067 3021162 ChemDiv3_001388 CN1CNC(=NS(=O)(=O)c2ccc(NC(=O)C)cc2)NC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P03 compound treatment 824294.0 218000.0 0.46 417059.0 -223000.0 -0.51 -0.0309 -0.0451 1145842 ChemDiv3_001389 CCCCn1c(Br)nc2n(C)c(=O)[nH]c(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P04 compound treatment 920130.0 314000.0 0.67 509547.0 -130000.0 -0.3 0.2614 0.359 1326168 ChemDiv3_001390 CCOC(=O)c1[nH]c(C(=O)O)c(CC)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P05 compound treatment 833833.0 228000.0 0.48 469171.0 -170000.0 -0.39 0.0672 0.1085 3119352 ChemDiv3_001391 CC1=CC(=O)C=C(C)C1=NS(=O)(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P06 compound treatment 1014895.0 409000.0 0.87 446924.0 -193000.0 -0.44 0.3028 0.3119 1659137 ChemDiv3_001392 CC(C)CC(=O)N1CCN(Cc2ccc(Cl)cc2)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P07 compound treatment 1225245.0 619000.0 1.31 451853.0 -188000.0 -0.43 0.6261 0.4537 1602384 ChemDiv3_001393 COc1cccc(c1)C(=O)NCCN2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P08 compound treatment 890970.0 285000.0 0.6 476540.0 -163000.0 -0.37 0.1647 0.2324 3119353 ChemDiv3_001394 CC1CCc2sc(NC(=O)C(Cc3ccccc3)Cc4ccccc4)c(C#N)c2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P09 compound treatment 311681.0 -295000.0 -0.62 275796.0 -364000.0 -0.83 -1.0264 -0.9904 3021163 ChemDiv3_001395 CCOC(=O)c1c(oc2ccc(O)c(CSCC(=O)Nc3ccccc3)c12)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P10 compound treatment 307602.0 -299000.0 -0.63 304882.0 -335000.0 -0.76 -0.9858 -0.9958 3119354 ChemDiv3_001396 Cc1cccc(c1)C(=O)Sc2cccccc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P11 compound treatment 1112197.0 506000.0 1.07 630010.0 -9610.0 -0.02 0.743 0.6926 1345562 ChemDiv3_001397 Cc1ccc(o1)c2c(C#N)c(SCC=C)nc3CCCCc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P12 compound treatment 1006657.0 400000.0 0.85 642679.0 3060.0 0.01 0.6052 0.7129 1469960 ChemDiv3_001398 CN1CCN(CCCN2C(SCC2=O)c3ccc(F)cc3)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P13 compound treatment 836517.0 230000.0 0.49 974482.0 335000.0 0.76 0.8835 0.9769 1737932 ChemDiv3_001399 COC(=O)COc1ccc2c(=O)c(coc2c1)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P14 compound treatment 1040058.0 434000.0 0.92 1028814.0 389000.0 0.88 1.276 0.9998 1405560 ChemDiv3_001400 Cc1ccc(OCC(O)CN2C(=O)NC(C)(C)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P15 compound treatment 1031571.0 425000.0 0.9 1052353.0 413000.0 0.94 1.3011 0.9998 1711766 ChemDiv3_001401 CCc1nc(cc2cc(OC)c(OC)cc12)c3ccc(OC)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P16 compound treatment 1169801.0 564000.0 1.19 1159592.0 520000.0 1.18 1.6807 1.0 3021164 ChemDiv3_001402 Cc1ccc(cc1C)S(=O)(=O)N2CCCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P17 compound treatment 974865.0 369000.0 0.78 1047353.0 408000.0 0.93 1.2081 0.9964 1435290 ChemDiv3_001403 CC1(C)Cc2c(sc3ncn4nc(nc4c23)c5ccccc5)C(C)(C)N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P18 compound treatment 900128.0 294000.0 0.62 1062895.0 423000.0 0.96 1.121 0.9779 1603940 ChemDiv3_001404 COc1ccccc1NC(=O)C2c3ccccc3Oc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P19 compound treatment 836196.0 230000.0 0.49 1203290.0 564000.0 1.28 1.2509 0.9123 3119355 ChemDiv3_001405 CC(C)Oc1ccc(cc1)C2CC(=O)NNC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P20 compound treatment 836981.0 231000.0 0.49 953431.0 314000.0 0.71 0.8504 0.9831 1788078 ChemDiv3_001406 Cc1ccc(cc1S(=O)(=O)N2CCCC2)S(=O)(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P21 compound treatment 818724.0 212000.0 0.45 1053799.0 414000.0 0.94 0.9844 0.943 3021165 ChemDiv3_001407 O=C(NN1C(=O)/C(=C\c2cccnc2)/SC1=S)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P22 compound treatment 625321.0 19100.0 0.04 512671.0 -127000.0 -0.29 -0.1755 -0.602 1314274 ChemDiv3_001408 COc1ccc(cc1)n2nc3ccc(NC(=O)c4ccc(cc4)c5ccccc5)cc3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P23 mock treatment 477879.0 -128000.0 -0.27 507201.0 -132000.0 -0.3 -0.4053 -0.9987 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2004 P24 mock treatment 460605.0 -146000.0 -0.31 423612.0 -216000.0 -0.49 -0.5656 -0.975 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A01 compound treatment 564616.0 -278000.0 -0.59 676103.0 -178000.0 -0.41 -0.703 -0.9834 1172919 ChemDiv3_001409 COc1ccc(cc1OC)C(=O)Nc2ccc(cc2)c3nc4cc(C)cc(C)c4o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A02 compound treatment 680974.0 -161000.0 -0.34 692113.0 -162000.0 -0.37 -0.5029 -0.9993 1360520 ChemDiv3_001410 CC(C)C1C(NC(CC1=O)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A03 compound treatment 1022908.0 181000.0 0.38 890221.0 35800.0 0.08 0.3282 0.8388 1912544 ChemDiv3_001411 OC(=O)CSCCc1ccncc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A04 compound treatment 1027640.0 185000.0 0.39 1001136.0 147000.0 0.33 0.5136 0.9967 1141661 ChemDiv3_001412 Clc1cccc2n(c3ccc(Br)cc3)c4nc(=O)[nH]c(=O)c4cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A05 compound treatment 1187635.0 345000.0 0.73 1006271.0 152000.0 0.35 0.7617 0.9412 3021166 ChemDiv3_001413 CC1(C)CC(=O)C(=CNCCN2CCOCC2)C(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A06 compound treatment 827566.0 -14800.0 -0.03 986733.0 132000.0 0.3 0.1905 0.6298 3119497 ChemDiv3_001414 CC(O)c1cccc(NC(=O)c2cnn3C(CC(Nc23)c4cccs4)C(F)(F)F)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A07 compound treatment 898495.0 56100.0 0.12 1077844.0 223000.0 0.51 0.4433 0.8497 1556247 ChemDiv3_001415 COc1cccc(c1)C(=O)Nc2ccc(cc2)c3cn4ccccc4n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A08 compound treatment 2605759.0 1760000.0 3.74 2519829.0 1670000.0 3.79 5.3208 1.0 1464561 ChemDiv3_001416 CC(=O)Nc1cc2ccc(OC(=O)C)cc2oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A09 compound treatment 1109490.0 267000.0 0.57 1228199.0 374000.0 0.85 1.0013 0.9805 3021167 ChemDiv3_001417 Cc1cc(c(C#N)c(=S)[nH]1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A10 compound treatment 1096952.0 255000.0 0.54 1216731.0 362000.0 0.82 0.9641 0.979 1216127 ChemDiv3_001418 CC(=O)N(Cc1ccccc1)C2CCCc3c2[nH]c4ccc(C)cc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A11 compound treatment 1102882.0 260000.0 0.55 1227560.0 373000.0 0.85 0.9904 0.9784 1428104 ChemDiv3_001419 O=C(Nn1cnc2ccccc2c1=O)C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A12 compound treatment 934059.0 91700.0 0.19 874936.0 20500.0 0.05 0.1704 0.8528 3119498 ChemDiv3_001420 CCOc1cc(/C=C\2/SC(=O)NC2=O)ccc1OCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A13 compound treatment 843408.0 1010.0 0.0 816123.0 -38300.0 -0.09 -0.06 -0.6896 3021168 ChemDiv3_001421 O=C1CC(CC(=O)C1=CNCc2ccco2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A14 compound treatment 952354.0 110000.0 0.23 1253836.0 399000.0 0.91 0.807 0.8607 3119499 ChemDiv3_001422 CC(C)c1ccc(/C=C\2/N(C(=O)C)C(=S)NC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A15 compound treatment 978673.0 136000.0 0.29 1298260.0 444000.0 1.01 0.9179 0.8744 1202793 ChemDiv3_001423 Cn1c(NC(=O)c2ccccc2NC(=O)c3ccccc3)nc4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A16 compound treatment 1050288.0 208000.0 0.44 1235455.0 381000.0 0.87 0.9242 0.9509 1785399 ChemDiv3_001424 CCC(Nc1n[nH]c(=O)[nH]c1=O)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A17 compound treatment 940229.0 97800.0 0.21 1309974.0 456000.0 1.04 0.8791 0.8322 1694993 ChemDiv3_001425 Clc1c(cnn(c2ccccc2)c1=O)N3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A18 compound treatment 1174852.0 332000.0 0.7 1077119.0 223000.0 0.51 0.8564 0.9868 3119500 ChemDiv3_001426 O=C1/C(=C\NCc2ccccc2)/Sc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A19 compound treatment 1124786.0 282000.0 0.6 1300490.0 446000.0 1.01 1.1405 0.9684 1385512 ChemDiv3_001427 O=C(Nc1ccc2nn(nc2c1)c3ccccc3)C(c4ccccc4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A20 compound treatment 916462.0 74100.0 0.16 1074061.0 220000.0 0.5 0.4642 0.8866 3021169 ChemDiv3_001428 Brc1ccccc1c2nc3sc4CCCc4c3c(=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A21 compound treatment 616814.0 -226000.0 -0.48 645151.0 -209000.0 -0.48 -0.6746 -1.0 1737060 ChemDiv3_001429 CN1CCc2c(C1)sc3NC(NC(=O)c23)c4ccc(OC(=O)c5ccccc5Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A22 compound treatment 836756.0 -5650.0 -0.01 952856.0 98500.0 0.22 0.1498 0.6683 3021170 ChemDiv3_001430 CCOC(=O)c1c(N/C=C\2/C(=O)N(C)c3ccccc23)scc1c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A23 mock treatment 544424.0 -298000.0 -0.63 750035.0 -104000.0 -0.24 -0.6144 -0.9106 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 A24 mock treatment 387515.0 -455000.0 -0.96 515205.0 -339000.0 -0.77 -1.2272 -0.9939 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B01 compound treatment 564233.0 -278000.0 -0.59 619006.0 -235000.0 -0.54 -0.7954 -0.9988 3119501 ChemDiv3_001431 CCOc1ccc(/C=N\n2c(C)nnc2C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B02 compound treatment 367673.0 -475000.0 -1.01 494340.0 -360000.0 -0.82 -1.2905 -0.9947 3119502 ChemDiv3_001432 CCOc1ccc(/C=C/2\SC(=NC2=O)Nc3cccc(C)c3C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B03 compound treatment 948824.0 106000.0 0.23 867383.0 13000.0 0.03 0.1804 0.7929 3021171 ChemDiv3_001433 Cc1ccc(CN2CCN(CC2)/N=C\C=C\c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B04 compound treatment 967172.0 125000.0 0.26 993399.0 139000.0 0.32 0.4105 0.9961 3119503 ChemDiv3_001434 Cn1/c(=N/C(=O)CCSc2ccccc2)/sc3cc(Cl)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B05 compound treatment 1123207.0 281000.0 0.6 1050251.0 196000.0 0.45 0.7358 0.9898 1384175 ChemDiv3_001435 Cc1cc(C)n(n1)C(=O)CNC(=O)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B06 compound treatment 676271.0 -166000.0 -0.35 668305.0 -186000.0 -0.42 -0.5482 -0.9958 3119504 ChemDiv3_001436 CC(C)(C)n1nc2CSCc2c1NC(=O)/C=C/c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B07 compound treatment 1387197.0 545000.0 1.15 1067227.0 213000.0 0.48 1.1588 0.9254 1576625 ChemDiv3_001437 Cc1ccc(C)c(c1)C(=O)COC(=O)c2cccc(n2)C(=O)OCC(=O)c3cc(C)ccc3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B08 compound treatment 1053444.0 211000.0 0.45 1092757.0 238000.0 0.54 0.6996 0.9955 1569810 ChemDiv3_001438 Clc1ccc(COc2ccc3c4CCCc4c(=O)oc3c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B09 compound treatment 1233547.0 391000.0 0.83 1035878.0 181000.0 0.41 0.8781 0.9481 1294258 ChemDiv3_001439 Brc1cc(Br)c2cccnc2c1OC(=O)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B10 compound treatment 1394340.0 552000.0 1.17 1605548.0 751000.0 1.71 2.035 0.983 3119505 ChemDiv3_001440 COc1cc([o+]c2ccccc12)c3ccc(cc3)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B11 compound treatment 728245.0 -114000.0 -0.24 716479.0 -138000.0 -0.31 -0.3928 -0.9918 3119506 ChemDiv3_001441 C(N1C2=NCCCN2c3ccccc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B12 compound treatment 1157539.0 315000.0 0.67 1073517.0 219000.0 0.5 0.8247 0.9896 3021172 ChemDiv3_001442 Clc1ccc2sc(cc(=O)c2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B13 compound treatment 278102.0 -564000.0 -1.2 249265.0 -605000.0 -1.38 -1.8187 -0.9976 1656193 ChemDiv3_001443 CC(C)(C)c1ccc(Cn2c(=N)n(CCO)c3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B14 compound treatment 1001271.0 159000.0 0.34 1057348.0 203000.0 0.46 0.5644 0.988 1367556 ChemDiv3_001444 Cc1nn(C(=O)C2(CC3CC4CC(C3)C2)C4)c(C)c1Sc5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B15 compound treatment 1042908.0 201000.0 0.43 1058234.0 204000.0 0.46 0.6283 0.9991 3119507 ChemDiv3_001445 O=C1OC2(CCCC2)OC(=O)C1=Cc3c[nH]c4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B16 compound treatment 1127230.0 285000.0 0.6 1081145.0 227000.0 0.52 0.7915 0.9969 1164014 ChemDiv3_001446 COc1ccc(Cn2c3ccccc3c4nc5ccccc5nc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B17 compound treatment 986277.0 144000.0 0.31 920913.0 66500.0 0.15 0.3226 0.9476 1193371 ChemDiv3_001447 CN(C)c1ccc(CNc2ccc3n(cnc3c2)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B18 compound treatment 949176.0 107000.0 0.23 1025227.0 171000.0 0.39 0.4347 0.967 3119508 ChemDiv3_001448 CCN(CC)c1nc2c(C)cccn2c(=O)c1/C=N/O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B19 compound treatment 691670.0 -151000.0 -0.32 740603.0 -114000.0 -0.26 -0.4089 -0.9945 3021173 ChemDiv3_001449 CCCOc1ccc(/C=C/C(=O)Nc2nccs2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B20 compound treatment 959390.0 117000.0 0.25 805136.0 -49300.0 -0.11 0.0962 0.3535 1665994 ChemDiv3_001450 C=CCN(CC=C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2ccccc2c3nc4ccccc4[nH]3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B21 compound treatment 972429.0 130000.0 0.28 882179.0 27800.0 0.06 0.2396 0.8472 1144767 ChemDiv3_001451 Cn1cc(C(=O)c2ccccc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B22 compound treatment 847458.0 5060.0 0.01 854578.0 185.0 0.0 0.0079 0.7343 1499357 ChemDiv3_001452 CC(=O)N1CCN(CC1)C(=S)c2ccc(o2)c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B23 mock treatment 924920.0 82500.0 0.17 855713.0 1320.0 0.0 0.1258 0.7191 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 B24 mock treatment 452473.0 -390000.0 -0.83 695442.0 -159000.0 -0.36 -0.8401 -0.9311 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C01 compound treatment 439970.0 -402000.0 -0.85 460874.0 -394000.0 -0.89 -1.2359 -0.9997 1424763 ChemDiv3_001453 Ic1ccc(Nc2nc3nonc3nc2N4CCCCC4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C02 compound treatment 135506.0 -707000.0 -1.5 131485.0 -723000.0 -1.64 -2.2218 -0.9989 3021226 ChemDiv3_001454 CCN/1CCS\C1=C/C=C/C2=[N+](CC)CCS2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C03 compound treatment 258434.0 -584000.0 -1.24 286612.0 -568000.0 -1.29 -1.7882 -0.9998 1048602 ChemDiv3_001455 CCCCc1oc2ccccc2c1C(=O)c3ccc(O)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C04 compound treatment 972393.0 130000.0 0.28 959106.0 105000.0 0.24 0.3632 0.9973 1647191 ChemDiv3_001456 CC(C)(C)C1CCc2nc(N)c3c(=O)oc4ccccc4c3c2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C05 compound treatment 942329.0 99900.0 0.21 955105.0 101000.0 0.23 0.3117 0.9992 1247277 ChemDiv3_001457 COc1cccc(c1)C2N(C(=O)C)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C06 compound treatment 1036752.0 194000.0 0.41 1176186.0 322000.0 0.73 0.8087 0.9631 3119509 ChemDiv3_001458 CCC(C)NC(=O)c1nn2C(CC(Nc2c1Cl)c3ccc(OC)cc3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C07 compound treatment 1025844.0 183000.0 0.39 1122068.0 268000.0 0.61 0.7053 0.9766 1174490 ChemDiv3_001459 COc1ccc(cc1)C2CC(=NN2S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C08 compound treatment 1025682.0 183000.0 0.39 1074644.0 220000.0 0.5 0.6288 0.9921 3021227 ChemDiv3_001460 O=C/1SC(=N\C1=C\c2ccco2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C09 compound treatment 604879.0 -238000.0 -0.5 679957.0 -174000.0 -0.4 -0.6365 -0.993 1606754 ChemDiv3_001461 COc1ccc(Nc2cc(C)c(C#N)c3nc4ccccc4n23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C10 compound treatment 946952.0 105000.0 0.22 1110078.0 256000.0 0.58 0.5678 0.9126 3021228 ChemDiv3_001462 CN(C)/C=C\1/Nc2ccccc2C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C11 compound treatment 1202196.0 360000.0 0.76 1178252.0 324000.0 0.74 1.06 0.9998 3119510 ChemDiv3_001463 Clc1ccccc1/C=C/C(=O)Nn2cnc3ccccc3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C12 compound treatment 1766048.0 924000.0 1.96 1218661.0 364000.0 0.83 1.9702 0.9267 3021229 ChemDiv3_001464 C/C(=C\c1ccccc1)/C=C\2/SC(=O)NC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C13 compound treatment 1290774.0 448000.0 0.95 1129870.0 275000.0 0.63 1.115 0.9795 3119511 ChemDiv3_001465 CC(C)CCNC=C1C(=O)CC(CC1=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C14 compound treatment 1083978.0 242000.0 0.51 1342490.0 488000.0 1.11 1.1468 0.9383 3119512 ChemDiv3_001466 CC(=O)N/1C(=S)NC(=O)\C1=C/c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C15 compound treatment 1102823.0 260000.0 0.55 1252437.0 398000.0 0.9 1.0303 0.9719 1388103 ChemDiv3_001467 COc1ccc(cc1)n2c(nc3ccccc3c2=O)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C16 compound treatment 112426.0 -730000.0 -1.55 120914.0 -733000.0 -1.67 -2.2734 -0.9993 3119513 ChemDiv3_001468 CN1CCN(Cc2c(O)ccc3c(=O)c(c4ccc(Cl)cc4Cl)c(oc23)C(F)(F)F)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C17 compound treatment 1114677.0 272000.0 0.58 1190142.0 336000.0 0.76 0.9479 0.9905 1040451 ChemDiv3_001469 Clc1c(cnn(c2ccccc2)c1=O)N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C18 compound treatment 265286.0 -577000.0 -1.22 254117.0 -600000.0 -1.36 -1.8301 -0.9985 3119818 ChemDiv3_001470 CCC(=O)Oc1ccc(Br)cc1/C=C/2\Sc3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C19 compound treatment 1090667.0 248000.0 0.53 1264317.0 410000.0 0.93 1.0312 0.9634 1725871 ChemDiv3_001471 CC(C)(C)c1ccc(OCC(=O)Nc2ccc3c(c2)oc4ccccc43)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C20 compound treatment 1206730.0 364000.0 0.77 1186349.0 332000.0 0.75 1.0798 0.9999 3021230 ChemDiv3_001472 CCOC(=O)c1c(C)n(CC)c2ccc(OC)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C21 compound treatment 1189821.0 347000.0 0.74 1095439.0 241000.0 0.55 0.9083 0.9894 1698973 ChemDiv3_001473 Nc1ccc2nc(SCc3cccc(F)c3)sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C22 compound treatment 1080155.0 238000.0 0.5 1160424.0 306000.0 0.7 0.8484 0.9875 3119657 ChemDiv3_001474 CN1C(=O)/C(=C/Nc2cccc3ccccc23)/c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C23 mock treatment 1073402.0 231000.0 0.49 970498.0 116000.0 0.26 0.5329 0.958 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 C24 mock treatment 738393.0 -104000.0 -0.22 770427.0 -84000.0 -0.19 -0.2909 -0.9974 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D01 compound treatment 613857.0 -229000.0 -0.48 728474.0 -126000.0 -0.29 -0.545 -0.9685 3021231 ChemDiv3_001475 CCc1ccc(/C=N/N2CCN(Cc3ccccc3)CC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D02 compound treatment 534901.0 -308000.0 -0.65 657759.0 -197000.0 -0.45 -0.7771 -0.9831 3119658 ChemDiv3_001476 COC(=O)CCN1C(=O)/C(=C\c2cccs2)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D03 compound treatment 676992.0 -165000.0 -0.35 853051.0 -1340.0 0.0 -0.2501 -0.7132 3119659 ChemDiv3_001477 Clc1ccc(CN2CCN(CC2)/N=C\3/C(=O)Nc4ccccc34)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D04 compound treatment 1046771.0 204000.0 0.43 1086228.0 232000.0 0.53 0.6791 0.9953 1518636 ChemDiv3_001478 CCOC(=O)C1CCN(CC1)C(=S)NC2Cc3ccccc3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D05 compound treatment 992478.0 150000.0 0.32 1101017.0 247000.0 0.56 0.6215 0.964 1671796 ChemDiv3_001479 Cc1cc(C)n(n1)C(=O)CNC(=O)COc2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D06 compound treatment 975087.0 133000.0 0.28 969202.0 115000.0 0.26 0.3835 0.9993 1229552 ChemDiv3_001480 Cc1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D07 compound treatment 956189.0 114000.0 0.24 1205231.0 351000.0 0.8 0.7346 0.8815 1448199 ChemDiv3_001481 O=C(c1ccccc1)c2ccc(Oc3cc(C#N)c4ccccc4n3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D08 compound treatment 988964.0 147000.0 0.31 1151573.0 297000.0 0.68 0.6975 0.9379 1186512 ChemDiv3_001482 OC(=O)COc1cc2oc(=O)c3CCCc3c2cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D09 compound treatment 897824.0 55400.0 0.12 717921.0 -136000.0 -0.31 -0.1363 -0.4109 1377235 ChemDiv3_001483 CCCCn1c(N)nc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D10 compound treatment 960555.0 118000.0 0.25 1127084.0 273000.0 0.62 0.6155 0.9205 1023460 ChemDiv3_001484 Cc1cc(cc([o+]1)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D11 compound treatment 510046.0 -332000.0 -0.7 608036.0 -246000.0 -0.56 -0.8943 -0.9935 3021232 ChemDiv3_001485 Brc1ccc(s1)C(=O)CN2C3=NCCCN3c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D12 compound treatment 537534.0 -305000.0 -0.65 771551.0 -82800.0 -0.19 -0.5902 -0.8767 1192182 ChemDiv3_001486 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(N2CCCC2)c3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D13 compound treatment 213221.0 -629000.0 -1.33 199410.0 -655000.0 -1.49 -1.9961 -0.9985 1376656 ChemDiv3_001487 CCCCn1c(=N)n(CCOc2ccccc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D14 compound treatment 676973.0 -165000.0 -0.35 604980.0 -249000.0 -0.57 -0.649 -0.9733 1598019 ChemDiv3_001488 CC(=O)Oc1ccc2c(=O)c(c(C)oc2c1C)c3ccccc3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D15 compound treatment 1174458.0 332000.0 0.7 1302224.0 448000.0 1.02 1.2177 0.9838 3119660 ChemDiv3_001489 CCOC(=O)C1=NNC2C1C(=O)N(C2=O)c3cccc(Cl)c3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D16 compound treatment 1046291.0 204000.0 0.43 1190559.0 336000.0 0.76 0.8461 0.9636 1618279 ChemDiv3_001490 Cc1ccc2nc(Cl)c(CC3CC(=NN3C(=O)CCCC(=O)O)c4ccccc4)cc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D17 compound treatment 570266.0 -272000.0 -0.58 659547.0 -195000.0 -0.44 -0.7212 -0.9915 1508458 ChemDiv3_001491 Cc1ccc(cc1)n2cnc3cc(NC(=O)c4ccccc4)ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D18 compound treatment 991405.0 149000.0 0.32 1231386.0 377000.0 0.86 0.8294 0.908 1297401 ChemDiv3_001492 Cc1cc(OCc2c(F)cccc2Cl)c3c4CCCCc4c(=O)oc3c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D19 compound treatment 1000734.0 158000.0 0.34 1096158.0 242000.0 0.55 0.626 0.972 1442148 ChemDiv3_001493 Cc1cccc(c1)N2COc3ccc4ccccc4c3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D20 compound treatment 1134153.0 292000.0 0.62 1085303.0 231000.0 0.52 0.8086 0.9967 1177599 ChemDiv3_001494 COc1ccccc1C(=O)Nc2c3CSCc3nn2c4ccc(Oc5ccccc5)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D21 compound treatment 1029749.0 187000.0 0.4 1093224.0 239000.0 0.54 0.6648 0.9882 1313552 ChemDiv3_001495 O=C(Cn1c2ncnn2c3ccccc13)c4ccc(cc4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D22 compound treatment 1096285.0 254000.0 0.54 945320.0 90900.0 0.21 0.5268 0.9136 1124488 ChemDiv3_001496 CSc1nc2ccc3nc(NC(=O)c4ccccc4C)sc3c2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D23 mock treatment 775528.0 -66900.0 -0.14 824031.0 -30400.0 -0.07 -0.1491 -0.9453 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 D24 mock treatment 702618.0 -140000.0 -0.3 699092.0 -155000.0 -0.35 -0.4592 -0.9962 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E01 compound treatment 800566.0 -41800.0 -0.09 748640.0 -106000.0 -0.24 -0.2327 -0.9081 1465681 ChemDiv3_001497 Brc1ccc(NC(=O)c2ccc3nsnc3c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E02 compound treatment 785430.0 -57000.0 -0.12 853303.0 -1090.0 0.0 -0.0872 -0.7215 1437302 ChemDiv3_001498 Clc1nc(NCCN2CCOCC2)nc(NC3CCCCC3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E03 compound treatment 926180.0 83800.0 0.18 1024569.0 170000.0 0.39 0.3992 0.9376 1173233 ChemDiv3_001499 S=C(Nc1ccccc1)Nc2ccc3c(c2)oc4ccccc43 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E04 compound treatment 1017676.0 175000.0 0.37 1112621.0 258000.0 0.59 0.6779 0.9756 1598038 ChemDiv3_001500 CCOc1cccc(c1)C(=O)Oc2cccc3ccc(C)nc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E05 compound treatment 850698.0 8300.0 0.02 936184.0 81800.0 0.19 0.1439 0.7705 1192729 ChemDiv3_001501 CC(C)OC(=O)C1=C(C)OC23OC(=C(C#N)C31C(=O)c4ccccc42)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E06 compound treatment 1001237.0 159000.0 0.34 1168512.0 314000.0 0.71 0.7431 0.9411 1490936 ChemDiv3_001502 CCC(C)C1NC(=O)NC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E07 compound treatment 970442.0 128000.0 0.27 1038586.0 184000.0 0.42 0.4881 0.978 3119661 ChemDiv3_001503 Cc1ccc2nc(O)c(C3=NN(C(C3)c4ccccc4)C(=O)CCC(=O)O)c(c5ccccc5)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E08 compound treatment 1371254.0 529000.0 1.12 1099665.0 245000.0 0.56 1.1871 0.948 1449149 ChemDiv3_001504 CCC(=O)Nc1ccc(cc1NC(=O)CC)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E09 compound treatment 159920.0 -682000.0 -1.45 160118.0 -694000.0 -1.58 -2.1392 -0.9991 1579424 ChemDiv3_001505 Cc1c(Cc2ccccc2)c(Cl)n3c4ccccc4nc3c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E10 compound treatment 906059.0 63700.0 0.13 1170228.0 316000.0 0.72 0.6032 0.8255 3119662 ChemDiv3_001506 CCN1C(=O)/C(=C\C=C\c2ccccc2Cl)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E11 compound treatment 1381231.0 539000.0 1.14 1370076.0 516000.0 1.17 1.6368 0.9999 1182144 ChemDiv3_001507 Cc1cc(N2CCOCC2)c3c(N)cc(C)c(C)c3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E12 compound treatment 1247183.0 405000.0 0.86 1182224.0 328000.0 0.75 1.1338 0.9975 3021233 ChemDiv3_001508 COc1cc(/C=C\2/SC(=S)NC2=O)ccc1OC(=O)c3cccc(C)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E13 compound treatment 1532415.0 690000.0 1.46 1284670.0 430000.0 0.98 1.7261 0.9809 1369185 ChemDiv3_001509 CCNCC(O)c1cccc(OC(=O)c2ccccc2C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E14 compound treatment 1494684.0 652000.0 1.38 1210585.0 356000.0 0.81 1.5504 0.9675 3119663 ChemDiv3_001510 CCN1C(=O)/C(=C/2\NC(=S)NC2=O)/c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E15 compound treatment 1151015.0 309000.0 0.65 1086164.0 232000.0 0.53 0.8352 0.9942 1448713 ChemDiv3_001511 CC(=O)Nc1ccccc1C(=O)N(Cc2ccccc2)Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E16 compound treatment 110268.0 -732000.0 -1.55 116425.0 -738000.0 -1.68 -2.2839 -0.9992 3119664 ChemDiv3_001512 Cc1ccccc1/N=C/2\C(=O)N(CN3CCCCC3)c4ccc(Br)cc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E17 compound treatment 1096296.0 254000.0 0.54 1170425.0 316000.0 0.72 0.8887 0.9899 3021234 ChemDiv3_001513 Clc1c(cn[nH]c1=O)N2CCCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E18 compound treatment 862686.0 20300.0 0.04 849839.0 -4550.0 -0.01 0.0231 0.5219 3119665 ChemDiv3_001514 C/C(=C/1\Sc2ccccc2C1=O)/Nc3ccc(C)cc3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E19 compound treatment 678136.0 -164000.0 -0.35 655892.0 -199000.0 -0.45 -0.5654 -0.9918 1455795 ChemDiv3_001515 O=C(COc1ccc2ccccc2c1)Nc3cccc(c3)c4nc5ncccc5o4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E20 compound treatment 950994.0 109000.0 0.23 961225.0 107000.0 0.24 0.3345 0.9996 1548836 ChemDiv3_001516 CCOC(=O)c1c(C)n(c2ccc(OC)cc2)c3ccc(OC)cc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E21 compound treatment 976528.0 134000.0 0.28 1007737.0 153000.0 0.35 0.4476 0.9949 3021235 ChemDiv3_001517 Nc1ccc2nc(SCc3ccccc3Cl)sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E22 compound treatment 996268.0 154000.0 0.33 946288.0 91900.0 0.21 0.3784 0.9768 3119666 ChemDiv3_001518 O=C/1OC(=N\C1=C/Nc2ccccc2)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E23 mock treatment 1056316.0 214000.0 0.45 895477.0 41100.0 0.09 0.3867 0.8352 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 E24 mock treatment 720386.0 -122000.0 -0.26 738853.0 -116000.0 -0.26 -0.3687 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F01 compound treatment 890449.0 48000.0 0.1 602838.0 -252000.0 -0.57 -0.3324 -0.5722 3119667 ChemDiv3_001519 Clc1cccc(/C=N/N2CCN(Cc3ccccc3)CC2)c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F02 compound treatment 940340.0 97900.0 0.21 1067034.0 213000.0 0.48 0.4887 0.9288 3021236 ChemDiv3_001520 Brc1cccc(/C=C/2\SC(=S)N(CC(=O)N3CCCc4ccccc34)C2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F03 compound treatment 907439.0 65000.0 0.14 1045580.0 191000.0 0.43 0.4049 0.8878 3119668 ChemDiv3_001521 C(N1CCN(CC1)/N=C/C=C/c2ccccc2)c3cccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F04 compound treatment 1020154.0 178000.0 0.38 1057474.0 203000.0 0.46 0.5929 0.9949 1686599 ChemDiv3_001522 O=C(NCc1n[nH]c(=S)n1c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F05 compound treatment 1039133.0 197000.0 0.42 1056133.0 202000.0 0.46 0.6192 0.9989 1371196 ChemDiv3_001523 CCOc1ccc(cc1)C(=O)NCC(=O)n2nc(C)cc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F06 compound treatment 1188134.0 346000.0 0.73 1171384.0 317000.0 0.72 1.0279 1.0 1292858 ChemDiv3_001524 Clc1ccc(cc1)n2nc3CSCc3c2NC(=O)Cc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F07 compound treatment 1106639.0 264000.0 0.56 1148021.0 294000.0 0.67 0.8681 0.9962 1135980 ChemDiv3_001525 COc1cccc(c1)C(=O)Nc2ccc(Cc3ccc(NC(=O)c4cccc(OC)c4)cc3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F08 compound treatment 1445861.0 603000.0 1.28 1143608.0 289000.0 0.66 1.3696 0.9521 3021237 ChemDiv3_001526 CC(C)C(N1C(=O)/C(=C/c2ccc(C)cc2)/SC1=S)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F09 compound treatment 1148469.0 306000.0 0.65 1100669.0 246000.0 0.56 0.8547 0.9973 1387806 ChemDiv3_001527 Nc1nc2ccccc2n1CCN3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F10 compound treatment 1049599.0 207000.0 0.44 1224978.0 371000.0 0.84 0.9064 0.9539 3119819 ChemDiv3_001528 Cc1ccccc1C2CC(=O)NC(=C2C#N)SCC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F11 compound treatment 1456122.0 614000.0 1.3 1142869.0 288000.0 0.66 1.3838 0.9497 1175819 ChemDiv3_001529 CCn1c2nc(C)c(C(=O)OC)n2c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F12 compound treatment 1621308.0 779000.0 1.65 1491447.0 637000.0 1.45 2.1918 0.9979 3021293 ChemDiv3_001530 COc1cc(/C=C/2\SC(=S)N(C(C(C)C)C(=O)O)C2=O)cc(OC)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F13 compound treatment 655173.0 -187000.0 -0.4 787252.0 -67100.0 -0.15 -0.3886 -0.9138 1207608 ChemDiv3_001531 Cc1ccc(OCCn2c(N)nc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F14 compound treatment 1502709.0 660000.0 1.4 1290141.0 436000.0 0.99 1.6904 0.9857 3021294 ChemDiv3_001532 CC(=O)Oc1ccc2c(=O)c(c3ccccc3)c(oc2c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F15 compound treatment 1158291.0 316000.0 0.67 1384104.0 530000.0 1.2 1.3251 0.9616 1429215 ChemDiv3_001533 Brc1cccc(NC(=O)C2C(=C2c3ccccc3)c4ccccc4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F16 compound treatment 1478037.0 636000.0 1.35 1221061.0 367000.0 0.83 1.5423 0.9734 1221702 ChemDiv3_001534 COc1ccc(cc1)C2=NN(C(C2)c3cc4ccccc4nc3Cl)C(=O)c5cccs5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F17 compound treatment 987996.0 146000.0 0.31 1173761.0 319000.0 0.73 0.7317 0.9274 1912856 ChemDiv3_001535 Clc1ccccc1S(=O)(=O)NC(=O)NCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F18 compound treatment 1251790.0 409000.0 0.87 1097988.0 244000.0 0.55 1.0053 0.9765 3021295 ChemDiv3_001536 COC(=O)C1=C(C)N(C)C(=S)NC1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F19 compound treatment 991746.0 149000.0 0.32 928013.0 73600.0 0.17 0.3422 0.9556 3021296 ChemDiv3_001537 C=CCn1c(=S)n(CC=C)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F20 compound treatment 894812.0 52400.0 0.11 881926.0 27500.0 0.06 0.1228 0.9631 1512592 ChemDiv3_001538 CC(C)C(=O)Nc1c2CSCc2nn1c3ccc(Oc4ccccc4)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F21 compound treatment 1197085.0 355000.0 0.75 1170072.0 316000.0 0.72 1.0392 0.9997 1573297 ChemDiv3_001539 c1coc(c1)c2cn3ccc4ccccc4c3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F22 compound treatment 1037853.0 195000.0 0.41 937524.0 83100.0 0.19 0.4266 0.9368 1238343 ChemDiv3_001540 CSc1nc2ccc3nc(NC(=O)c4ccccc4Cl)sc3c2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F23 mock treatment 1067898.0 225000.0 0.48 943912.0 89500.0 0.2 0.4819 0.9276 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 F24 mock treatment 819015.0 -23400.0 -0.05 799052.0 -55300.0 -0.13 -0.124 -0.9171 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G01 compound treatment 1000472.0 158000.0 0.34 873575.0 19200.0 0.04 0.2678 0.7924 3119820 ChemDiv3_001541 COC(=O)c1cc(ccc1Cl)c2ccc(/C=C\3/C(=C(C#N)C(=O)N=C3O)C)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G02 compound treatment 284152.0 -558000.0 -1.18 274356.0 -580000.0 -1.32 -1.7693 -0.9985 3021297 ChemDiv3_001542 COc1nc(Nc2ccc3OCOc3c2)nc(OC)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G03 compound treatment 907499.0 65100.0 0.14 877542.0 23100.0 0.05 0.1348 0.9127 1468410 ChemDiv3_001543 CC1(C)CC(=O)C=C(C1)NCC2CCN(CC2)C(=S)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G04 compound treatment 954112.0 112000.0 0.24 936094.0 81700.0 0.19 0.2988 0.9928 3119821 ChemDiv3_001544 CCOC(=O)c1cc2NC(CC(n2n1)C(F)(F)F)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G05 compound treatment 1165753.0 323000.0 0.69 1005856.0 151000.0 0.34 0.7282 0.9493 3021298 ChemDiv3_001545 CC(C)OC(=O)CSc1nc2ccccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G06 compound treatment 1562520.0 720000.0 1.53 997196.0 143000.0 0.32 1.3091 0.8387 3119822 ChemDiv3_001546 CCc1ccc(cc1)N2N(O)c3ccccc3NC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G07 compound treatment 1262193.0 420000.0 0.89 937642.0 83200.0 0.19 0.7631 0.8387 1165154 ChemDiv3_001547 Cc1cc(C)cc(CC2CC(=O)N(CCc3ccc4OCOc4c3)C2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G08 compound treatment 1484554.0 642000.0 1.36 1361554.0 507000.0 1.15 1.7779 0.9966 1431964 ChemDiv3_001548 CC(=O)N1CC2(NC(=O)c3ccccc3N2)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G09 compound treatment 1866816.0 1020000.0 2.17 1716548.0 862000.0 1.96 2.9217 0.9987 1737262 ChemDiv3_001549 Cc1cc(NCCO)n2c3ccccc3nc2c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G10 compound treatment 1153688.0 311000.0 0.66 1249540.0 395000.0 0.9 1.1019 0.9885 3119823 ChemDiv3_001550 CCN1C(=O)/C(=C\c2ccsc2)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G11 compound treatment 884202.0 41800.0 0.09 982999.0 129000.0 0.29 0.2694 0.8818 3119824 ChemDiv3_001551 O=C1CC(CC(=O)C1=CNCc2ccncc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G12 compound treatment 1224219.0 382000.0 0.81 1012892.0 158000.0 0.36 0.8272 0.9336 3021299 ChemDiv3_001552 COc1ccc(cc1)N2C(=O)/C(=C\C=C\c3ccccc3)/SC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G13 compound treatment 1336764.0 494000.0 1.05 1158950.0 305000.0 0.69 1.2307 0.9798 3119825 ChemDiv3_001553 COc1ccc(/C=c/2\oc3cccc4c(OC)ccc(c2=O)c34)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G14 compound treatment 926414.0 84000.0 0.18 939999.0 85600.0 0.19 0.2636 0.999 1172050 ChemDiv3_001554 CCOC(=O)c1ccc(Nc2ncnc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G15 compound treatment 1084327.0 242000.0 0.51 1065556.0 211000.0 0.48 0.7021 0.9995 3119826 ChemDiv3_001555 COc1cc(/C=C/2\SC(=S)NC2=O)ccc1OCc3cccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G16 compound treatment 978026.0 136000.0 0.29 951946.0 97600.0 0.22 0.3601 0.9918 3119827 ChemDiv3_001556 O=C/1N(CN2CCOCC2)c3ccccc3\C1=N\c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G17 compound treatment 1184791.0 342000.0 0.73 1073699.0 219000.0 0.5 0.8658 0.9832 3021300 ChemDiv3_001557 CC1=C(C(NC(=S)N1)c2ccc(F)cc2)C(=O)Nc3cccc(Cl)c3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G18 compound treatment 1108020.0 266000.0 0.56 767463.0 -86900.0 -0.2 0.2584 0.433 3119828 ChemDiv3_001558 CC(=O)N(/N=C/1\Sc2ccccc2C1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G19 compound treatment 1435439.0 593000.0 1.26 983729.0 129000.0 0.29 1.0969 0.8496 1604755 ChemDiv3_001559 O=C(COc1ccc2ccccc2c1)Nc3ccc4nn(nc4c3)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G20 compound treatment 1013349.0 171000.0 0.36 834744.0 -19600.0 -0.04 0.2247 0.6153 1447009 ChemDiv3_001560 CCOC(=O)c1c(C)n(Cc2ccccc2)c3ccc(OC(=O)C)cc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G21 compound treatment 1210120.0 368000.0 0.78 907551.0 53200.0 0.12 0.6367 0.8071 3119829 ChemDiv3_001561 CCc1ccc(cc1)N2NC(=O)/C(=C\c3c(C)c(C#N)c4nc5ccccc5n4c3O)/C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G22 compound treatment 1040708.0 198000.0 0.42 824363.0 -30000.0 -0.07 0.249 0.5846 3021301 ChemDiv3_001562 CC/1=NN(C(=S)\C1=C\Nc2cccc(Br)c2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G23 mock treatment 735942.0 -106000.0 -0.23 757375.0 -97000.0 -0.22 -0.3156 -0.9999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 G24 mock treatment 671296.0 -171000.0 -0.36 821713.0 -32700.0 -0.07 -0.309 -0.8346 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H01 compound treatment 723732.0 -119000.0 -0.25 1160987.0 307000.0 0.7 0.315 0.4251 3119830 ChemDiv3_001563 Oc1ccc2ccccc2c1/C=N/N3CCN(Cc4ccccc4)CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H02 compound treatment 237337.0 -605000.0 -1.28 275008.0 -579000.0 -1.32 -1.8385 -0.9999 1322139 ChemDiv3_001564 CCOC(=O)c1c(C)n(c2ccccc2)c3ccc(OC(=O)c4ccccc4NC(=O)CC)cc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H03 compound treatment 1143628.0 301000.0 0.64 1261817.0 407000.0 0.93 1.1065 0.9835 3119831 ChemDiv3_001565 C1CN(CCN1/N=C\c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H04 compound treatment 1143378.0 301000.0 0.64 1170309.0 316000.0 0.72 0.9591 0.9983 3119832 ChemDiv3_001566 CCOc1ccc2n(C)/c(=N/C(=O)c3cc4ccccc4cc3OC)/sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H05 compound treatment 751423.0 -91000.0 -0.19 521347.0 -333000.0 -0.76 -0.6718 -0.8598 1575164 ChemDiv3_001567 O=C(Sc1ccc(Oc2ccc(SC(=O)c3ccco3)cc2)cc1)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H06 compound treatment 1357024.0 515000.0 1.09 1099234.0 245000.0 0.56 1.1651 0.9512 1615009 ChemDiv3_001568 CC(C)(C)n1nc2CSCc2c1NC(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H07 compound treatment 1514333.0 672000.0 1.42 1257656.0 403000.0 0.92 1.6556 0.9773 1373227 ChemDiv3_001569 OC(=O)C1CCCCC1C(=O)Nc2cccc(c2)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H08 compound treatment 1562919.0 721000.0 1.53 1332030.0 478000.0 1.09 1.848 0.986 1684031 ChemDiv3_001570 OCc1cc(=O)c(O)c(o1)C(Nc2ccccn2)c3ccccc3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H09 compound treatment 128841.0 -714000.0 -1.51 131654.0 -723000.0 -1.64 -2.2316 -0.9991 1601378 ChemDiv3_001571 OC(Cn1c(=N)n(Cc2ccccc2)c3ccccc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H10 compound treatment 973626.0 131000.0 0.28 1269131.0 415000.0 0.94 0.8635 0.8783 3119833 ChemDiv3_001572 CCOc1ccc(cc1)c2c(C#N)c(N)nc(SCC(=O)c3ccc(Cl)cc3)c2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H11 compound treatment 749437.0 -93000.0 -0.2 843163.0 -11200.0 -0.03 -0.1574 -0.7921 1449806 ChemDiv3_001573 COc1ccc(cc1)C(=O)Cn2c(=N)n(CC=C)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H12 compound treatment 1364097.0 522000.0 1.11 1553714.0 699000.0 1.59 1.9063 0.9843 3119834 ChemDiv3_001574 Cc1ccc(Sc2c(nc3sccn23)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H13 compound treatment 529413.0 -313000.0 -0.66 540419.0 -314000.0 -0.71 -0.9739 -0.9993 1668029 ChemDiv3_001575 Nc1nc2ccccc2n1CCOc3ccc(Br)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H14 compound treatment 1295882.0 453000.0 0.96 1328414.0 474000.0 1.08 1.4418 0.9984 3119835 ChemDiv3_001576 COc1ccc2c(=O)c(c3ccccc3C)c(oc2c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H15 compound treatment 1506365.0 664000.0 1.41 1444006.0 590000.0 1.34 1.9432 0.9997 3021302 ChemDiv3_001577 Brc1cccc(c1)N2C(=O)C3C(C(C=CC3c4ccccc4)c5ccccc5)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H16 compound treatment 1095852.0 253000.0 0.54 1028709.0 174000.0 0.4 0.6602 0.9888 3119836 ChemDiv3_001578 Cc1ccc(cc1)C2CC(=NN2C(=O)c3ccc(Br)o3)c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H17 compound treatment 866236.0 23800.0 0.05 1074311.0 220000.0 0.5 0.3893 0.7746 1123601 ChemDiv3_001579 CCOC(=O)CNc1ccc(cc1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H18 compound treatment 1269677.0 427000.0 0.91 1182912.0 329000.0 0.75 1.1686 0.9954 3119837 ChemDiv3_001580 Clc1ccc(cc1)C(=O)/C=C/C=C/c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H19 compound treatment 139484.0 -703000.0 -1.49 137475.0 -717000.0 -1.63 -2.2062 -0.999 3119838 ChemDiv3_001581 Cc1ccc(O)c(c1)c2cc(nc(n2)c3ccccc3)C(F)(F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H20 compound treatment 1005887.0 163000.0 0.35 948924.0 94500.0 0.21 0.397 0.9736 3021303 ChemDiv3_001582 Cc1ccc(c(C)c1)n2nc3CSCc3c2NC(=O)Cc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H21 compound treatment 1199695.0 357000.0 0.76 981771.0 127000.0 0.29 0.7404 0.913 1718858 ChemDiv3_001583 Cc1nc2n(CCN3CCOCC3)c4ccccc4n2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H22 compound treatment 960684.0 118000.0 0.25 919547.0 65200.0 0.15 0.2821 0.9685 1657446 ChemDiv3_001584 O=C(Nc1ccc(cc1)c2nc3ccccc3o2)c4ccc(Oc5ccccc5)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H23 mock treatment 919545.0 77100.0 0.16 777163.0 -77200.0 -0.18 -0.0085 -0.0355 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 H24 mock treatment 791029.0 -51400.0 -0.11 952864.0 98500.0 0.22 0.0813 0.3265 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I01 compound treatment 1034166.0 192000.0 0.41 1157007.0 303000.0 0.69 0.774 0.9685 1538533 ChemDiv3_001585 COc1ccc(cc1)C2NC(=S)NC(=C2C(=O)N)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I02 compound treatment 1267064.0 425000.0 0.9 1401122.0 547000.0 1.24 1.5155 0.9875 3119978 ChemDiv3_001586 Cc1cccc(CSCc2nnc(NC(=O)/C=C/c3ccccc3)s2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I03 compound treatment 1221293.0 379000.0 0.8 1281741.0 427000.0 0.97 1.255 0.9955 3021304 ChemDiv3_001587 CC1(C)CC(=O)C(=CNCCN2CCN(CC2)C(=O)Nc3ccc(Cl)c(Cl)c3)C(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I04 compound treatment 1282393.0 440000.0 0.93 1328800.0 474000.0 1.08 1.4222 0.9974 3119979 ChemDiv3_001588 FC(F)(F)c1c2CCc3ccccc3-c2nc4cc(nn14)C(=O)Nc5ccc(Cl)cc5Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I05 compound treatment 1292846.0 450000.0 0.95 1150873.0 296000.0 0.67 1.1519 0.9855 1590870 ChemDiv3_001589 CCOc1ccc2c(=O)c(Oc3ccc(OC)cc3)coc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I06 compound treatment 1463664.0 621000.0 1.32 1137442.0 283000.0 0.64 1.3863 0.9457 3119980 ChemDiv3_001590 CC(C)N1C(=O)/C(=C/c2cccc(Br)c2)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I07 compound treatment 1100763.0 258000.0 0.55 1435225.0 581000.0 1.32 1.3211 0.9241 3119981 ChemDiv3_001591 OC(=O)C(CC(=O)Nc1cccc(c1)C(F)(F)F)Cc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I08 compound treatment 1878201.0 1040000.0 2.2 1472594.0 618000.0 1.41 2.5465 0.9768 3427363 ChemDiv3_001592 COc1cc2CCN3CC4N(CCc5cc(OC)c(OC)cc45)CC3c2cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I09 compound treatment 698717.0 -144000.0 -0.3 757196.0 -97200.0 -0.22 -0.3716 -0.9876 1494132 ChemDiv3_001593 N#Cc1c2CCCc2c(Nc3ccccc3)n4c5ccccc5nc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I10 compound treatment 1559450.0 717000.0 1.52 1420395.0 566000.0 1.29 1.9848 0.9966 3119982 ChemDiv3_001594 C/C(=C\c1ccccc1)/C=C\2/SC(=S)N(C3CCCCC3)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I11 compound treatment 1734359.0 892000.0 1.89 1177454.0 323000.0 0.73 1.8564 0.9152 3021305 ChemDiv3_001595 O=C1CC(CC(=O)C1=CNCCN2CCOCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I12 compound treatment 1347571.0 505000.0 1.07 1159991.0 306000.0 0.69 1.2486 0.9781 3119983 ChemDiv3_001596 O=C/1N\C(=N/c2ccccc2)\S\C1=C\c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I13 compound treatment 1248444.0 406000.0 0.86 1177893.0 324000.0 0.74 1.1287 0.9969 3021306 ChemDiv3_001597 COc1ccc2c(=O)/c(=C/c3ccc4OCOc4c3)/oc5cccc1c52 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I14 compound treatment 1235703.0 393000.0 0.83 1198813.0 344000.0 0.78 1.1433 0.9995 1203947 ChemDiv3_001598 CC(C)Nc1nc(nc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I15 compound treatment 1766251.0 924000.0 1.96 1087780.0 233000.0 0.53 1.7601 0.8674 3021307 ChemDiv3_001599 COc1cc(/C=c\2/sc3nc4ccccc4n3c2=O)cc(OC)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I16 compound treatment 1332676.0 490000.0 1.04 1014477.0 160000.0 0.36 0.9923 0.9011 3119984 ChemDiv3_001600 CN(C)CN1C(=O)/C(=N\c2ccc3ccccc3c2)/c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I17 compound treatment 1831354.0 989000.0 2.1 1204169.0 350000.0 0.8 2.0448 0.9119 1726741 ChemDiv3_001601 O=C(NCc1ccncc1)C2c3ccccc3Oc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I18 compound treatment 1102393.0 260000.0 0.55 883214.0 28800.0 0.07 0.4361 0.7856 3021308 ChemDiv3_001602 CCOc1ccc(cc1)N(/C=C/2\Sc3ccccc3C2=O)C(=O)c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I19 compound treatment 1274080.0 432000.0 0.92 1096967.0 243000.0 0.55 1.0371 0.9706 1339625 ChemDiv3_001603 Fc1ccccc1C(=O)Nc2ccc3OCCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I20 compound treatment 1264306.0 422000.0 0.89 1052614.0 198000.0 0.45 0.9511 0.9497 1713175 ChemDiv3_001604 COc1ccc2n(c(C)c(C(=O)O)c2c1)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I21 compound treatment 1397900.0 555000.0 1.18 1015517.0 161000.0 0.37 1.0917 0.8852 3119985 ChemDiv3_001605 OC(=O)c1ccc(cc1)n2nnnc2SCC(=O)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I22 compound treatment 1197796.0 355000.0 0.75 949541.0 95100.0 0.22 0.6857 0.8748 3119986 ChemDiv3_001606 CCOC(=O)c1ccc(NC=C2C(=O)NC(=O)NC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I23 mock treatment 1132372.0 290000.0 0.61 950421.0 96000.0 0.22 0.5891 0.903 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 I24 mock treatment 1199067.0 357000.0 0.76 995256.0 141000.0 0.32 0.7611 0.9269 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J01 compound treatment 978947.0 137000.0 0.29 921356.0 67000.0 0.15 0.3123 0.955 3021309 ChemDiv3_001607 Cc1ccc(/C=N/N2CCN(Cc3ccccc3)CC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J02 compound treatment 1191800.0 349000.0 0.74 1397796.0 543000.0 1.24 1.3974 0.9701 1644734 ChemDiv3_001608 C=CCNC(=O)c1cc(=O)c2ccccc2o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J03 compound treatment 1141997.0 300000.0 0.64 1215996.0 362000.0 0.82 1.0304 0.9919 3021310 ChemDiv3_001609 COc1ccccc1/C=C/C=N\N2CCN(CC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J04 compound treatment 1091588.0 249000.0 0.53 1240560.0 386000.0 0.88 0.9944 0.9704 1423874 ChemDiv3_001610 O=C(CCOc1ccccc1)Nc2nc3c(ccc4ccccc34)s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J05 compound treatment 1126618.0 284000.0 0.6 1210918.0 357000.0 0.81 0.9992 0.9893 1201781 ChemDiv3_001611 O=C(COC(=O)c1ccccc1Nc2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J06 compound treatment 981664.0 139000.0 0.3 864409.0 10000.0 0.02 0.2249 0.7594 1685020 ChemDiv3_001612 CC(C)(C)c1ccc(cc1)C(=O)Nc2c3CSCc3nn2c4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J07 compound treatment 1429910.0 588000.0 1.25 1342733.0 488000.0 1.11 1.6658 0.9984 1369848 ChemDiv3_001613 COc1ccc(NC(=O)c2ccc(cc2)N3C(=O)c4ccccc4C3=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J08 compound treatment 1281022.0 439000.0 0.93 1301087.0 447000.0 1.02 1.3756 0.999 3021370 ChemDiv3_001614 CC(N1C(=O)/C(=C\c2ccc(C)o2)/SC1=S)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J09 compound treatment 1273701.0 431000.0 0.91 1524438.0 670000.0 1.52 1.7237 0.9702 1352921 ChemDiv3_001615 COC(=O)Cn1c(=N)n(C)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J10 compound treatment 1198663.0 356000.0 0.76 1360092.0 506000.0 1.15 1.347 0.9792 1463142 ChemDiv3_001616 COC(=O)C1C(C(=C(NC1=O)SCc2ccccc2)C#N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J11 compound treatment 198007.0 -644000.0 -1.37 200731.0 -654000.0 -1.49 -2.0168 -0.9991 1215092 ChemDiv3_001617 C=CCn1c(=N)n(CC(=O)c2ccc(cc2)c3ccccc3)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J12 compound treatment 146635.0 -696000.0 -1.47 156838.0 -698000.0 -1.59 -2.1644 -0.9993 3021371 ChemDiv3_001618 COc1ccc(cc1)C(=O)On2c(cc3ccccc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J13 compound treatment 1902145.0 1060000.0 2.25 1464876.0 610000.0 1.39 2.57 0.9732 1340086 ChemDiv3_001619 O=C(Nc1ccccc1C(=O)NC2CCCCC2)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J14 compound treatment 1601674.0 759000.0 1.61 1509529.0 655000.0 1.49 2.1914 0.9992 3021372 ChemDiv3_001620 Oc1ccccc1/C=C/2\N=C3CCCCCN3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J15 compound treatment 1237494.0 395000.0 0.84 1177580.0 323000.0 0.73 1.1118 0.9979 1558867 ChemDiv3_001621 Cc1cc(C)cc(NC(=O)Nc2ccccc2C(=O)Nc3cc(C)cc(C)c3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J16 compound treatment 1311737.0 469000.0 0.99 1322287.0 468000.0 1.06 1.4558 0.9994 1137505 ChemDiv3_001622 Cc1ccc(cc1)C2=NN(C(C2)c3cn(nc3c4ccc(C)cc4)c5ccccc5)C(=O)CCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J17 compound treatment 1820383.0 978000.0 2.07 1498182.0 644000.0 1.46 2.501 0.9855 1319284 ChemDiv3_001623 Cc1cc(O)ccc1n2c(=O)c3cc4c(=O)n(c5ccc(O)cc5C)c(=O)c4cc3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J18 compound treatment 1478740.0 636000.0 1.35 1246217.0 392000.0 0.89 1.5838 0.9797 1596958 ChemDiv3_001624 CC1CCc2nc(NC(=O)c3ccc(cc3)S(=O)(=O)N(CC=C)CC=C)sc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J19 compound treatment 1355621.0 513000.0 1.09 1079791.0 225000.0 0.51 1.1317 0.941 3021373 ChemDiv3_001625 FC(F)(F)C1(CC(=O)c2ccco2)NCCN1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J20 compound treatment 1042300.0 200000.0 0.42 960545.0 106000.0 0.24 0.4703 0.9644 3119987 ChemDiv3_001626 Cc1ccc(cc1)n2nc3CSCc3c2NC(=O)/C=C\c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J21 compound treatment 1463221.0 621000.0 1.32 1041000.0 187000.0 0.42 1.2306 0.89 3021374 ChemDiv3_001627 O=C(CCCN1C(=O)/C(=C\c2cccs2)/SC1=S)N3CCCc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J22 compound treatment 1299604.0 457000.0 0.97 1104865.0 250000.0 0.57 1.088 0.9679 3119988 ChemDiv3_001628 Cn1/c(=N\C(=O)c2ccc(cc2)S(=O)(=O)N3CCCCC3)/sc4c1ccc5ccccc45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J23 mock treatment 1310063.0 468000.0 0.99 999341.0 145000.0 0.33 0.9341 0.8941 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 J24 mock treatment 892881.0 50500.0 0.11 1083062.0 229000.0 0.52 0.4433 0.8351 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K01 compound treatment 679998.0 -162000.0 -0.34 530983.0 -323000.0 -0.74 -0.7634 -0.9402 1467244 ChemDiv3_001629 CC(C)(C)c1cc(cc(c1)S(=O)(=O)CCc2ccccn2)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K02 compound treatment 900172.0 57800.0 0.12 953794.0 99400.0 0.23 0.2464 0.9586 3021375 ChemDiv3_001630 Fc1ccccc1CSCc2nnc(NC(=O)/C=C/c3ccccc3)s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K03 compound treatment 938009.0 95600.0 0.2 1025639.0 171000.0 0.39 0.4186 0.9537 3119989 ChemDiv3_001631 CCCC/1=NN(C(=O)\C1=C\N(C)C)c2nc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K04 compound treatment 1302003.0 460000.0 0.97 1259927.0 406000.0 0.92 1.3409 0.9996 3119990 ChemDiv3_001632 CC(C)OC(=O)c1cnn2c(cc(nc12)c3ccc(C)cc3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K05 compound treatment 1081855.0 239000.0 0.51 1043353.0 189000.0 0.43 0.6627 0.9966 1566112 ChemDiv3_001633 COC(=O)COc1ccc2c(=O)c(Oc3ccc(OC)cc3)coc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K06 compound treatment 968227.0 126000.0 0.27 1046255.0 192000.0 0.44 0.4971 0.9721 3119991 ChemDiv3_001634 O=S(=O)(NCc1ccccc1)c2ccc3OCCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K07 compound treatment 895775.0 53400.0 0.11 1024244.0 170000.0 0.39 0.3531 0.8774 1513154 ChemDiv3_001635 OC(=O)CN1C(=O)CC(Cc2ccc(Cl)cc2)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K08 compound treatment 1064247.0 222000.0 0.47 1065338.0 211000.0 0.48 0.6717 1.0 1680762 ChemDiv3_001636 COC(CN(C1CCCc2c1[nH]c3ccc(C)cc23)C(=O)C)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K09 compound treatment 960025.0 118000.0 0.25 1026339.0 172000.0 0.39 0.4527 0.9764 1379664 ChemDiv3_001637 CCc1c(C)c(C#N)c2nc3ccccc3n2c1n4ccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K10 compound treatment 1079829.0 237000.0 0.5 1113091.0 259000.0 0.59 0.7718 0.997 3119992 ChemDiv3_001638 CN(C)c1ccc(/C=C/C=C\2/SC(=S)N(C)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K11 compound treatment 1359248.0 517000.0 1.1 1192607.0 338000.0 0.77 1.3185 0.985 3119993 ChemDiv3_001639 Cc1ccc(SCC/2=NN(C(=O)\C2=C\NCc3ccco3)c4nc5ccccc5s4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K12 compound treatment 1327690.0 485000.0 1.03 1540701.0 686000.0 1.56 1.8308 0.9796 3021376 ChemDiv3_001640 OC(=O)COc1ccc(/C=C\2/NC(=S)NC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K13 compound treatment 1202604.0 360000.0 0.76 1159637.0 305000.0 0.69 1.0307 0.9989 3021377 ChemDiv3_001641 COc1ccc(cc1)C(=O)C(=C2Nc3ccccc3N2)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K14 compound treatment 1045770.0 203000.0 0.43 1452323.0 598000.0 1.36 1.2661 0.8878 3119994 ChemDiv3_001642 Oc1ccc2c(=O)c(c3ccc(Cl)cc3Cl)c(oc2c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K15 compound treatment 1141764.0 299000.0 0.63 1423970.0 570000.0 1.29 1.3644 0.9461 1190196 ChemDiv3_001643 COc1cc(OC)cc(c1)c2nc3ccccc3c(=O)n2OC(=O)c4ccccc4Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K16 compound treatment 1010091.0 168000.0 0.36 971516.0 117000.0 0.27 0.4397 0.9899 3021378 ChemDiv3_001644 O=C(CCN1C(=O)c2ccccc2C1=O)C(=C3Nc4ccccc4N3)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K17 compound treatment 1146291.0 304000.0 0.64 1127193.0 273000.0 0.62 0.8941 0.9998 1229182 ChemDiv3_001645 Cc1onc(c1C(=O)n2cnc3cc(C)c(C)cc23)c4ccccc4Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K18 compound treatment 1010470.0 168000.0 0.36 1026280.0 172000.0 0.39 0.5283 0.9989 1396504 ChemDiv3_001646 CCOC(=O)c1c(NC=O)scc1c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K19 compound treatment 1022979.0 181000.0 0.38 990151.0 136000.0 0.31 0.4889 0.9943 1614792 ChemDiv3_001647 COc1cc2ccccc2cc1C(=O)Nc3ccc4OCCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K20 compound treatment 1051844.0 209000.0 0.44 912161.0 57800.0 0.13 0.4068 0.8786 3021379 ChemDiv3_001648 CN1C(=O)/C(=C\NN2CCOCC2)/c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K21 compound treatment 1041520.0 199000.0 0.42 731377.0 -123000.0 -0.28 0.1007 0.1989 3120138 ChemDiv3_001649 CCN(CC)c1ccc(/C=C\2/C(=O)NN(C2=O)c3ccc(C)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K22 compound treatment 1059435.0 217000.0 0.46 911059.0 56700.0 0.13 0.4164 0.8716 1271860 ChemDiv3_001650 O=c1n(cnc2sc3CCCCc3c12)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K23 mock treatment 1002011.0 160000.0 0.34 843376.0 -11000.0 -0.03 0.2215 0.653 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 K24 mock treatment 858425.0 16000.0 0.03 647978.0 -206000.0 -0.47 -0.3078 -0.6542 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L01 compound treatment 858657.0 16300.0 0.03 1015637.0 161000.0 0.37 0.2836 0.7702 3120139 ChemDiv3_001651 CCOc1ccccc1/C=N\n2cnnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L02 compound treatment 931796.0 89400.0 0.19 1172050.0 318000.0 0.72 0.6447 0.8634 3120140 ChemDiv3_001652 COC(=O)c1ccccc1NC=C2C(=O)NC(=S)NC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L03 compound treatment 945705.0 103000.0 0.22 1130421.0 276000.0 0.63 0.5986 0.9006 3021380 ChemDiv3_001653 Cc1ccc(cc1)N2CCN(CC2)/N=C\C=C\c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L04 compound treatment 1045199.0 203000.0 0.43 1174625.0 320000.0 0.73 0.8188 0.9684 3120141 ChemDiv3_001654 CCOc1ccc2n(C)/c(=N\C(=O)CCOc3ccccc3)/sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L05 compound treatment 1230139.0 388000.0 0.82 1341706.0 487000.0 1.11 1.3647 0.9892 1125649 ChemDiv3_001655 CNc1ccccc1C(=O)OCC(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L06 compound treatment 977182.0 135000.0 0.29 913400.0 59000.0 0.13 0.2969 0.9406 1333133 ChemDiv3_001656 Clc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccc(cc4)C(=O)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L07 compound treatment 1095574.0 253000.0 0.54 1233168.0 379000.0 0.86 0.9884 0.9741 3021381 ChemDiv3_001657 CC(=O)N1N=C(N)SC21CCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L08 compound treatment 1049353.0 207000.0 0.44 1267757.0 413000.0 0.94 0.9748 0.9398 3120142 ChemDiv3_001658 COc1cccc(/C=C/2\SC(=S)N(C(Cc3ccccc3)C(=O)O)C2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L09 compound treatment 1069757.0 227000.0 0.48 1278948.0 425000.0 0.97 1.0233 0.9485 1735087 ChemDiv3_001659 Cc1ccc(Cn2c(=N)n(CC(=O)O)c3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L10 compound treatment 1031755.0 189000.0 0.4 1277241.0 423000.0 0.96 0.9636 0.925 1873281 ChemDiv3_001660 CCOC(=O)CSC1=C(C#N)C(C(C(=O)OC)C(=O)N1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L11 compound treatment 1085499.0 243000.0 0.52 1249969.0 396000.0 0.9 1.0004 0.9651 3021382 ChemDiv3_001661 C=CCn1c2nc(cn2c3ccccc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L12 compound treatment 864407.0 22000.0 0.05 1016129.0 162000.0 0.37 0.293 0.7905 1591933 ChemDiv3_001662 Cc1[nH]c2ccccc2c1CN3CCC(Cc4ccccc4)CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L13 compound treatment 1211605.0 369000.0 0.78 1542497.0 688000.0 1.56 1.6597 0.9488 1237818 ChemDiv3_001663 O=C(NCc1ccccc1)c2ccccc2NC(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L14 compound treatment 1176160.0 334000.0 0.71 1509342.0 655000.0 1.49 1.5532 0.9421 1564490 ChemDiv3_001664 COc1ccc(C)cc1S(=O)(=O)N2CCN(C)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L15 compound treatment 1208900.0 366000.0 0.78 1349319.0 495000.0 1.13 1.3451 0.9836 1447061 ChemDiv3_001665 COc1ccc(OC)c(Nc2nc3nonc3nc2N4CCC(C)CC4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L16 compound treatment 966486.0 124000.0 0.26 1115295.0 261000.0 0.59 0.6054 0.9331 1193553 ChemDiv3_001666 CC(C)c1cc(NS(=O)(=O)c2ccccc2)c(O)c(c1)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L17 compound treatment 1093123.0 251000.0 0.53 1277174.0 423000.0 0.96 1.0555 0.961 1642809 ChemDiv3_001667 O=C(OCc1nc2ccccc2[nH]1)C3(CC4CC5CC(C4)C3)C5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L18 compound treatment 1149300.0 307000.0 0.65 1431407.0 577000.0 1.31 1.3877 0.9477 3021383 ChemDiv3_001668 CCOC(=O)c1s/c(=N\C(=O)c2ccc(OCC)cc2)/n(C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L19 compound treatment 1124974.0 283000.0 0.6 1183778.0 329000.0 0.75 0.9531 0.9939 3120143 ChemDiv3_001669 COc1ccccc1NC(=O)c2cc3ccccc3c(/C=N/c4ccc(NC(=O)C)cc4)c2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L20 compound treatment 1001591.0 159000.0 0.34 1167206.0 313000.0 0.71 0.7415 0.942 1201425 ChemDiv3_001670 COc1ccc(CC(=O)Nc2c3CSCc3nn2c4ccc(C)cc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L21 compound treatment 1036703.0 194000.0 0.41 1234398.0 380000.0 0.86 0.9022 0.9426 3120144 ChemDiv3_001671 O=C(CCCN1C(=O)/C(=C/c2cccs2)/SC1=S)N3c4ccccc4Sc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L22 compound treatment 969651.0 127000.0 0.27 1138431.0 284000.0 0.65 0.6474 0.925 3021384 ChemDiv3_001672 Cc1cccc(NC(=S)NCCCN2CCOCC2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L23 mock treatment 913493.0 71100.0 0.15 1188017.0 334000.0 0.76 0.6429 0.8314 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 L24 mock treatment 798208.0 -44200.0 -0.09 1114890.0 260000.0 0.59 0.3525 0.5879 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M01 compound treatment 555826.0 -287000.0 -0.61 635692.0 -219000.0 -0.5 -0.7812 -0.9951 1915602 ChemDiv3_001673 CC(C)c1ccc(cc1)S(=O)(=O)CCc2ccc(C)[n+](C)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M02 compound treatment 838220.0 -4180.0 -0.01 970206.0 116000.0 0.26 0.1799 0.6829 3120145 ChemDiv3_001674 CC(C)(C)C(=O)Nc1nnc(SCc2ccc(Cl)cc2Cl)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M03 compound treatment 917047.0 74600.0 0.16 1121285.0 267000.0 0.61 0.541 0.8627 1626138 ChemDiv3_001675 CC(=C1C(=O)CC(C)(C)CC1=O)NCC2CCNCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M04 compound treatment 1013217.0 171000.0 0.36 1023872.0 169000.0 0.39 0.5285 0.9995 3021385 ChemDiv3_001676 CC1CCCCN1C(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M05 compound treatment 969621.0 127000.0 0.27 996809.0 142000.0 0.32 0.4197 0.9959 3120146 ChemDiv3_001677 CC(C)(C)c1cc(/C=C/2\SC(=S)NC2=O)cc(c1O)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M06 compound treatment 1042585.0 200000.0 0.42 1163556.0 309000.0 0.7 0.7971 0.9708 1369956 ChemDiv3_001678 OC(=O)c1ccccc1C(=O)Nc2ccc3OCCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M07 compound treatment 1134905.0 293000.0 0.62 1128008.0 274000.0 0.62 0.8783 1.0 3021386 ChemDiv3_001679 CC(C(Cc1cc(C)cc(C)c1)C(=O)O)C(=O)Nc2cccc(c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M08 compound treatment 997127.0 155000.0 0.33 1228123.0 374000.0 0.85 0.8328 0.9143 1367959 ChemDiv3_001680 CCOC(=O)c1c(C)sc2Sc3ccc(Cl)cc3Nc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M09 compound treatment 110444.0 -732000.0 -1.55 136081.0 -718000.0 -1.63 -2.252 -0.9997 1584915 ChemDiv3_001681 CCc1c(C)c(C#N)c2[nH]c3ccccc3n2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M10 compound treatment 990878.0 148000.0 0.31 1107854.0 253000.0 0.58 0.63 0.9595 3120147 ChemDiv3_001682 CN1C(=O)/C(=C\c2ccc(o2)c3ccc(C)c(Cl)c3)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M11 compound treatment 720257.0 -122000.0 -0.26 831036.0 -23400.0 -0.05 -0.2206 -0.8347 1579702 ChemDiv3_001683 CCC(=O)N1C(C2=C(CC(CC2=O)c3ccccc3)Nc4ccccc14)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M12 compound treatment 932675.0 90300.0 0.19 1230466.0 376000.0 0.86 0.7399 0.8445 1133651 ChemDiv3_001684 C(Cc1cccs1)Nc2ncnc3sc4CCCc4c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M13 compound treatment 1033841.0 191000.0 0.41 1141262.0 287000.0 0.65 0.7482 0.9739 3120148 ChemDiv3_001685 O=C(COc1ccccc1)C(=C2Nc3ccccc3N2)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M14 compound treatment 950963.0 109000.0 0.23 1150050.0 296000.0 0.67 0.638 0.898 3021387 ChemDiv3_001686 OC(=O)c1ccc(/N=C/2\SC(Cc3cccc(Cl)c3)C(=O)N2CC=C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M15 compound treatment 973990.0 132000.0 0.28 1140514.0 286000.0 0.65 0.6572 0.9286 1726607 ChemDiv3_001687 Cc1cccc(c1)c2nc3ccccc3c(=O)n2OC(=O)c4ccc(C)c(C)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M16 compound treatment 163117.0 -679000.0 -1.44 104010.0 -750000.0 -1.71 -2.2246 -0.9964 3120149 ChemDiv3_001688 CC1CN(CC(C)O1)C(=O)c2sc3cc(C)ccc3c2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M17 compound treatment 872881.0 30500.0 0.06 1126249.0 272000.0 0.62 0.4827 0.7768 1427209 ChemDiv3_001689 CC(C)CCNC(=O)C1c2ccccc2Oc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M18 compound treatment 905638.0 63200.0 0.13 1070288.0 216000.0 0.49 0.4419 0.8684 1691429 ChemDiv3_001690 CCOC(=O)c1c(C)c(C)sc1NC(=O)CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M19 compound treatment 1015466.0 173000.0 0.37 949486.0 95100.0 0.22 0.4123 0.9682 1389933 ChemDiv3_001691 Cc1ccc2cc(C(=O)N)c(=N)oc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M20 compound treatment 1019328.0 177000.0 0.38 987251.0 133000.0 0.3 0.4788 0.9942 3120150 ChemDiv3_001692 CCOC(=O)c1c(N/C=C\2/C(=O)N(C)c3ccccc23)sc4CCCc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M21 compound treatment 957390.0 115000.0 0.24 951064.0 96700.0 0.22 0.3278 0.9987 3021478 ChemDiv3_001693 CC/1=NN(C(=O)\C1=C\c2ccc(o2)c3cccc(Cl)c3C)c4cccc(c4)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M22 compound treatment 909726.0 67300.0 0.14 958145.0 104000.0 0.24 0.2677 0.971 3120151 ChemDiv3_001694 Cc1cccc(OCCOc2ccc(Br)cc2/C=C/3\SC(=S)NC3=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M23 mock treatment 906471.0 64100.0 0.14 916344.0 62000.0 0.14 0.1956 0.9998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 M24 mock treatment 649328.0 -193000.0 -0.41 868663.0 14300.0 0.03 -0.2665 -0.649 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N01 compound treatment 963905.0 122000.0 0.26 804629.0 -49800.0 -0.11 0.1021 0.363 3021479 ChemDiv3_001695 C(=N/n1cnnc1)\c2cccc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N02 compound treatment 1077321.0 235000.0 0.5 1093047.0 239000.0 0.54 0.7358 0.9991 3118032 ChemDiv3_001696 COc1ccc(cc1)n2nc3CSCc3c2NC(=O)c4ccccc4C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N03 compound treatment 1020420.0 178000.0 0.38 1085441.0 231000.0 0.53 0.6383 0.9868 3021480 ChemDiv3_001697 Clc1ccccc1CN2CCN(CC2)/N=C/C=C\c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N04 compound treatment 1049285.0 207000.0 0.44 1132289.0 278000.0 0.63 0.7569 0.9841 3117871 ChemDiv3_001698 Cn1/c(=N\C(=O)CCOc2ccccc2)/sc3cc(Br)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N05 compound treatment 1029756.0 187000.0 0.4 1058055.0 204000.0 0.46 0.6083 0.9971 1590935 ChemDiv3_001699 CCC(=O)c1ccc(OC(=O)C2c3ccccc3Oc4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N06 compound treatment 1054501.0 212000.0 0.45 1098993.0 245000.0 0.56 0.7112 0.9944 1201811 ChemDiv3_001700 Cc1cccc(COc2ccc3c(C)cc(=O)oc3c2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N07 compound treatment 618077.0 -224000.0 -0.48 677912.0 -176000.0 -0.4 -0.62 -0.9964 1923213 ChemDiv3_001701 OCCN1CCN(CC#CCn2c3ccccc3c4ccccc24)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N08 compound treatment 994329.0 152000.0 0.32 1277488.0 423000.0 0.96 0.9079 0.895 1578316 ChemDiv3_001702 O=C(CC(C1CCCCC1=O)c2ccco2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N09 compound treatment 1021275.0 179000.0 0.38 1183277.0 329000.0 0.75 0.7969 0.9505 1582025 ChemDiv3_001703 CCN(CC)CCCn1c(cn2c1nc3ccccc32)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N10 compound treatment 1079308.0 237000.0 0.5 1213390.0 359000.0 0.82 0.9323 0.9728 1873341 ChemDiv3_001704 COC(=O)C1C(C(=C(NC1=O)SCC=C)C#N)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N11 compound treatment 1053532.0 211000.0 0.45 1225474.0 371000.0 0.84 0.9131 0.956 1619409 ChemDiv3_001705 OCCn1c(=N)n(CC=C)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N12 compound treatment 1078558.0 236000.0 0.5 1405351.0 551000.0 1.25 1.2397 0.919 1130658 ChemDiv3_001706 O=c1c2ccccc2nc3c4ccccc4c(nn13)N5CCOCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N13 compound treatment 959957.0 118000.0 0.25 1172559.0 318000.0 0.72 0.6877 0.8989 1508826 ChemDiv3_001707 CCOC(=O)c1c(C)nn(Cc2cccc(Cl)c2)c1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N14 compound treatment 1075060.0 233000.0 0.49 1229935.0 376000.0 0.85 0.9525 0.966 1777814 ChemDiv3_001708 C/C(=C(\C#N)/c1nc2ccccc2[nH]1)/O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N15 compound treatment 1044986.0 203000.0 0.43 1186318.0 332000.0 0.75 0.8373 0.9643 1709331 ChemDiv3_001709 Cn1c(Sc2nnc(N)s2)nc3n(C)c(=O)n(C)c(=O)c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N16 compound treatment 988831.0 146000.0 0.31 1237495.0 383000.0 0.87 0.8354 0.9035 3117873 ChemDiv3_001710 COc1ccc(Nc2nc3c(C)cccn3c(=O)c2/C=N/Cc4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N17 compound treatment 909579.0 67200.0 0.14 998924.0 145000.0 0.33 0.3331 0.93 3117874 ChemDiv3_001711 COCc1cc(C)nc(SCC(=O)c2ccc(O)c(O)c2)c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N18 compound treatment 809962.0 -32400.0 -0.07 905211.0 50800.0 0.12 0.0331 0.2459 3021481 ChemDiv3_001712 CCOc1ccc2n(C)/c(=N\C(=O)c3ccc(cc3)S(=O)(=O)N4CCc5ccccc45)/sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N19 compound treatment 175896.0 -667000.0 -1.41 154101.0 -700000.0 -1.59 -2.1249 -0.9982 3117875 ChemDiv3_001713 CCCN1C/C(=C\c2ccc(OC)cc2)/C(=O)\C(=C/c3ccc(OC)cc3)\C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N20 compound treatment 1188383.0 346000.0 0.73 1105197.0 251000.0 0.57 0.9218 0.9923 1525047 ChemDiv3_001714 Cc1ccc(c(C)c1)n2nc3CSCc3c2NC(=O)COc4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N21 compound treatment 954507.0 112000.0 0.24 971158.0 117000.0 0.27 0.3558 0.9985 3021482 ChemDiv3_001715 Cc1cccc(NC2=NC(=O)/C(=C/c3ccc(F)cc3)/S2)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N22 compound treatment 1132032.0 290000.0 0.61 1053627.0 199000.0 0.45 0.7545 0.9888 1667814 ChemDiv3_001716 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)N4CCc5ccccc5C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N23 mock treatment 960160.0 118000.0 0.25 1059152.0 205000.0 0.47 0.5057 0.9573 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 N24 mock treatment 872001.0 29600.0 0.06 950586.0 96200.0 0.22 0.199 0.8747 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O01 compound treatment 891394.0 49000.0 0.1 868513.0 14100.0 0.03 0.0961 0.8844 3021483 ChemDiv3_001717 OC(=O)C/1=NN(C(=O)\C1=C\c2cccs2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O02 compound treatment 1067739.0 225000.0 0.48 1140690.0 286000.0 0.65 0.7981 0.9884 3117876 ChemDiv3_001718 CCOc1cc(C=C2C(=O)NC(=S)NC2=O)ccc1OCCOc3ccc(cc3)C(C)CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O03 compound treatment 1215368.0 373000.0 0.79 986552.0 132000.0 0.3 0.7716 0.9122 3021484 ChemDiv3_001719 CC1(C)CC(=O)C=C(C1)NCCCn2ccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O04 compound treatment 1127392.0 285000.0 0.6 1060756.0 206000.0 0.47 0.759 0.9922 3117877 ChemDiv3_001720 CC(C)NC(=O)c1cc2NC(CC(n2n1)C(F)(F)F)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O05 compound treatment 1182524.0 340000.0 0.72 1042993.0 189000.0 0.43 0.8131 0.9692 3021485 ChemDiv3_001721 CCOc1cc(/C=c\2/sc3nc4ccccc4n3c2=O)ccc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O06 compound treatment 1018887.0 176000.0 0.37 1119005.0 265000.0 0.6 0.69 0.9739 3117878 ChemDiv3_001722 CC(C)(C)C(O)(CC#CCN1CCCC1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O07 compound treatment 1086436.0 244000.0 0.52 1121231.0 267000.0 0.61 0.7948 0.9969 1383847 ChemDiv3_001723 CCOc1ccc(NC(=O)C(C)C(Cc2ccc(C)cc2)C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O08 compound treatment 1176424.0 334000.0 0.71 1054016.0 200000.0 0.45 0.8216 0.9769 1624938 ChemDiv3_001724 O=C1CCCN1CCNC(=S)Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O09 compound treatment 1191608.0 349000.0 0.74 1095568.0 241000.0 0.55 0.9112 0.9891 1249695 ChemDiv3_001725 CCC1(CC)Cc2ccccc2-c3[nH]c(=S)n(Cc4ccccc4)c(=O)c31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O10 compound treatment 1245469.0 403000.0 0.85 1051988.0 198000.0 0.45 0.9219 0.9549 3117879 ChemDiv3_001726 CN1C(=O)/C(=C\c2ccncc2)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O11 compound treatment 1148086.0 306000.0 0.65 1006332.0 152000.0 0.35 0.7025 0.9566 1610336 ChemDiv3_001727 CC(=O)Nc1ncc2C(=O)CC(Cc2n1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O12 compound treatment 1229549.0 387000.0 0.82 1196337.0 342000.0 0.78 1.1301 0.9996 1305118 ChemDiv3_001728 CCOc1ccc2c(=O)c(Oc3ccccc3Br)coc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O13 compound treatment 1096490.0 254000.0 0.54 1089910.0 236000.0 0.54 0.7595 1.0 3117880 ChemDiv3_001729 CC(N1C(=O)c2ccccc2C1=O)C(=O)C(=C3Nc4ccccc4N3)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O14 compound treatment 1013440.0 171000.0 0.36 1072051.0 218000.0 0.49 0.6063 0.9883 3021518 ChemDiv3_001730 Cc1ccc(cc1)n/2c(cs\c2=N\C(=O)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O15 compound treatment 1019228.0 177000.0 0.37 1057079.0 203000.0 0.46 0.5909 0.9948 1281278 ChemDiv3_001731 Clc1c(cnn(c2ccccc2)c1=O)N3CCN(CC3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O16 compound treatment 1001950.0 160000.0 0.34 1048612.0 194000.0 0.44 0.5514 0.9913 3021519 ChemDiv3_001732 COc1ccc(N/C=C\2/Sc3ccccc3C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O17 compound treatment 204409.0 -638000.0 -1.35 213208.0 -641000.0 -1.46 -1.9872 -0.9993 1330175 ChemDiv3_001733 CCC(C)c1ccc(NC(=O)c2cc3ccccc3o2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O18 compound treatment 277562.0 -565000.0 -1.2 244238.0 -610000.0 -1.39 -1.8276 -0.9973 1220991 ChemDiv3_001734 CCOC(=O)c1c(CC(C)C)csc1NC(=O)c2ccccc2OC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O19 compound treatment 1224586.0 382000.0 0.81 1093412.0 239000.0 0.54 0.9572 0.9811 3117881 ChemDiv3_001735 N/C(=N\O)/CCCN1CCCCC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O20 compound treatment 1266384.0 424000.0 0.9 901585.0 47200.0 0.11 0.7114 0.7859 3117882 ChemDiv3_001736 CCOC(=O)c1c(C)c(C)sc1N/C=C\2/C(=O)N(C)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O21 compound treatment 1137518.0 295000.0 0.63 937101.0 82700.0 0.19 0.5754 0.8807 1915686 ChemDiv3_001737 O=C(CSc1nnnn1c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O22 compound treatment 935751.0 93300.0 0.2 905313.0 50900.0 0.12 0.2218 0.9674 3021520 ChemDiv3_001738 Cc1nnc(C)n1/N=C\c2cccc(OCc3ccccc3)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O23 mock treatment 929967.0 87600.0 0.19 940709.0 86300.0 0.2 0.27 0.9996 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 O24 mock treatment 760024.0 -82400.0 -0.17 746409.0 -108000.0 -0.25 -0.2971 -0.9861 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P01 compound treatment 554186.0 -288000.0 -0.61 554631.0 -300000.0 -0.68 -0.914 -0.9985 3021521 ChemDiv3_001739 C(=N/n1cnnc1)\c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P02 compound treatment 921890.0 79500.0 0.17 953758.0 99400.0 0.23 0.2789 0.9896 1680808 ChemDiv3_001740 CC1CC(C)CN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccc(C)cc3C(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P03 compound treatment 1065950.0 224000.0 0.47 1048547.0 194000.0 0.44 0.6472 0.9994 3021522 ChemDiv3_001741 Cc1nnc(C)n1/N=C/c2cc(Br)cc(Br)c2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P04 compound treatment 1234165.0 392000.0 0.83 1243709.0 389000.0 0.89 1.2131 0.9995 3117883 ChemDiv3_001742 O=C(CN1C(=O)/C(=C/c2ccccc2)/SC1=S)NC3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P05 compound treatment 1162664.0 320000.0 0.68 1160456.0 306000.0 0.7 0.9721 0.9999 1137126 ChemDiv3_001743 Cc1cc(C)c(C)c(C(=O)COC(=O)c2cc(O)nc3ccccc23)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P06 compound treatment 1128351.0 286000.0 0.61 1201401.0 347000.0 0.79 0.9865 0.9915 1455967 ChemDiv3_001744 CCCc1cc(=O)oc2cc(OCC(=O)OCc3ccccc3)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P07 compound treatment 925789.0 83400.0 0.18 809501.0 -44900.0 -0.1 0.0528 0.2588 1311949 ChemDiv3_001745 OC(CN1CCCCC1)CN2c3ccccc3Sc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P08 compound treatment 940470.0 98100.0 0.21 938660.0 84300.0 0.19 0.2825 0.9992 3021523 ChemDiv3_001746 CN1/C(=C\C=C/2\C(=O)Oc3ccccc3C2=O)/C(C)(C)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P09 compound treatment 116450.0 -726000.0 -1.54 107011.0 -747000.0 -1.7 -2.2897 -0.9988 3117884 ChemDiv3_001747 Clc1ccc(cc1)c2cn3c(nc4ccccc43)n2CCCNC5CCCCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P10 compound treatment 1058452.0 216000.0 0.46 1319298.0 465000.0 1.06 1.0713 0.93 3021524 ChemDiv3_001748 Cc1cccn2c(=O)c(/C=N/O)c(nc12)N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P11 compound treatment 1011315.0 169000.0 0.36 1054561.0 200000.0 0.46 0.575 0.993 1157071 ChemDiv3_001749 OCCn1c(=N)n(Cc2ccc(Cl)cc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P12 compound treatment 1048930.0 207000.0 0.44 1319818.0 465000.0 1.06 1.0578 0.9237 3117885 ChemDiv3_001750 Cc1ccc(cc1)c2cnc(o2)c3ccc(Br)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P13 compound treatment 931141.0 88700.0 0.19 1080499.0 226000.0 0.51 0.4965 0.907 3021525 ChemDiv3_001751 C=CCn1cc(C=C2C(=O)OC3(CCCC3)OC2=O)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P14 compound treatment 1077822.0 235000.0 0.5 1382960.0 529000.0 1.2 1.2026 0.9242 3117886 ChemDiv3_001752 O/C(=C(/C#N)\c1nc2ccccc2[nH]1)/C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P15 compound treatment 1025568.0 183000.0 0.39 1277560.0 423000.0 0.96 0.9549 0.9204 1689476 ChemDiv3_001753 Cn1c(CCN)nc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P16 compound treatment 1036432.0 194000.0 0.41 1254118.0 400000.0 0.91 0.9335 0.9358 3118033 ChemDiv3_001754 CCN(CC)c1nc2c(C)cccn2c(=O)c1C=C3C(=O)NC(=O)NC3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P17 compound treatment 1029475.0 187000.0 0.4 1210291.0 356000.0 0.81 0.8526 0.9461 1463531 ChemDiv3_001755 CCc1ccc(OCC(=O)Nc2sc3CCCCc3c2C(=O)OC)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P18 compound treatment 954235.0 112000.0 0.24 1007642.0 153000.0 0.35 0.414 0.9824 1302503 ChemDiv3_001756 Cc1nc2c(ccc3nc(NC(=O)c4cccc(Oc5ccccc5)c4)sc32)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P19 compound treatment 1111971.0 270000.0 0.57 1055561.0 201000.0 0.46 0.7275 0.9939 3118034 ChemDiv3_001757 CCC(=O)N1N=C(CC1c2ccc(cc2)N(C)C)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P20 compound treatment 937963.0 95600.0 0.2 954657.0 100000.0 0.23 0.3044 0.9983 1354491 ChemDiv3_001758 O=C(Nc1c2CSCc2nn1c3ccc(Oc4ccccc4)cc3)c5ccco5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P21 compound treatment 995119.0 153000.0 0.32 1048296.0 194000.0 0.44 0.5407 0.9885 3118035 ChemDiv3_001759 Cc1cccc(NC2=NC(=O)/C(=C\3/C(=O)N(CC(=O)O)c4ccccc34)/S2)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P22 compound treatment 881783.0 39400.0 0.08 774082.0 -80300.0 -0.18 -0.0701 -0.349 3021526 ChemDiv3_001760 CCC(C)(C)n1c(=O)[nH]c2CCCc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P23 mock treatment 865505.0 23100.0 0.05 756905.0 -97500.0 -0.22 -0.1221 -0.5379 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2005 P24 mock treatment 526185.0 -316000.0 -0.67 512612.0 -342000.0 -0.78 -1.0235 -0.9973 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A01 compound treatment 343649.0 -363000.0 -0.77 378211.0 -430000.0 -0.98 -1.2363 -0.993 1658490 ChemDiv3_001761 Cc1cc(=O)[nH]c(Nc2ccccc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A02 compound treatment 330266.0 -377000.0 -0.8 451018.0 -357000.0 -0.81 -1.1393 -1.0 1465213 ChemDiv3_001762 CCOc1ccc2nc(Nc3nc(O)cc(O)n3)nc(C)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A03 compound treatment 380948.0 -326000.0 -0.69 412569.0 -396000.0 -0.9 -1.1252 -0.9915 3118036 ChemDiv3_001763 COc1cccc2s/c(=N/C(=O)Cc3cccc4ccccc34)/n(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A04 compound treatment 563707.0 -143000.0 -0.3 383221.0 -425000.0 -0.97 -0.8984 -0.8867 3118037 ChemDiv3_001764 NC1=NC(=O)CC(S1)C(=O)Nc2ccc(Br)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A05 compound treatment 539985.0 -167000.0 -0.35 496576.0 -312000.0 -0.71 -0.7517 -0.9486 1135271 ChemDiv3_001765 Oc1cc(Cc2nc3ccccc3s2)c(O)cc1Cc4nc5ccccc5s4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A06 compound treatment 378679.0 -328000.0 -0.7 396660.0 -412000.0 -0.94 -1.1541 -0.9894 1132838 ChemDiv3_001766 O=C(CSC#N)n1c2ccccc2c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A07 compound treatment 432315.0 -275000.0 -0.58 431500.0 -377000.0 -0.86 -1.0177 -0.9823 3118038 ChemDiv3_001767 O=S(=O)(/N=C(/NC(=S)OC1CCCCC1)\c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A08 compound treatment 443839.0 -263000.0 -0.56 413272.0 -395000.0 -0.9 -1.0298 -0.9738 3021527 ChemDiv3_001768 CC(C)COc1ccc(cc1)C(=S)N2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A09 compound treatment 525028.0 -182000.0 -0.39 502269.0 -306000.0 -0.7 -0.765 -0.9613 3021563 ChemDiv3_001769 COc1ccc(/C=C/C(=O)O)cc1S(=O)(=O)N(C)CCO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A10 compound treatment 590088.0 -117000.0 -0.25 677225.0 -131000.0 -0.3 -0.3862 -0.9958 3021564 ChemDiv3_001770 Cc1cc(C(=O)O)c(=O)[nH]c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A11 compound treatment 428866.0 -278000.0 -0.59 414731.0 -394000.0 -0.89 -1.0499 -0.9795 1689022 ChemDiv3_001771 Cc1ccc2n(CC(O)CNCc3ccco3)c(c(c4ccccc4)c2c1)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A12 compound treatment 167358.0 -540000.0 -1.14 161194.0 -647000.0 -1.47 -1.8495 -0.9923 3118039 ChemDiv3_001772 NNC(=O)CN1C(c2ccccc2)c3cc(Cl)ccc3N=C1c4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A13 compound treatment 433974.0 -273000.0 -0.58 441572.0 -367000.0 -0.83 -0.9991 -0.9841 1296978 ChemDiv3_001773 C=CCNC(=O)c1cc2ccccc2o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A14 compound treatment 435391.0 -272000.0 -0.58 453837.0 -355000.0 -0.81 -0.9772 -0.9864 3021565 ChemDiv3_001774 CCOC(=O)/C(=C/1\Nc2ccccc2C1=O)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A15 compound treatment 367056.0 -340000.0 -0.72 439248.0 -369000.0 -0.84 -1.1031 -0.9971 1549910 ChemDiv3_001775 CC(=O)Nc1ccc(NC(=O)C2(CCCC2)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A16 compound treatment 458028.0 -249000.0 -0.53 619292.0 -189000.0 -0.43 -0.6773 -0.9948 3021566 ChemDiv3_001776 Clc1ccc(cc1)N2C(=O)C3CC=CCC3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A17 compound treatment 557779.0 -149000.0 -0.32 631908.0 -176000.0 -0.4 -0.5075 -0.9931 3118040 ChemDiv3_001777 NC(=O)/C(=C/c1ccc2OCOc2c1)/NC(=O)c3ccc(Br)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A18 compound treatment 106237.0 -601000.0 -1.27 157695.0 -651000.0 -1.48 -1.9467 -0.9972 3021567 ChemDiv3_001778 O=C1C=C(N2CCOCC2)C(=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A19 compound treatment 475101.0 -232000.0 -0.49 440993.0 -367000.0 -0.84 -0.9383 -0.9681 1179633 ChemDiv3_001779 COc1cc(CN2CCN(CC2)C(=O)COc3ccccc3)cc(OC)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A20 compound treatment 453704.0 -253000.0 -0.54 422767.0 -386000.0 -0.88 -0.9997 -0.9724 3118041 ChemDiv3_001780 CC(C)(C)c1n[nH]c2OC(=C(C#N)C(c12)c3ccc(OC(=O)c4ccccc4Cl)cc3)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A21 compound treatment 377074.0 -330000.0 -0.7 410975.0 -397000.0 -0.9 -1.1335 -0.992 3021568 ChemDiv3_001781 Cc1ccc(cc1)C2C3=C(NC4=C2C(=O)CC(C)(C)C4)c5ccccc5C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A22 compound treatment 399206.0 -308000.0 -0.65 466961.0 -341000.0 -0.78 -1.0104 -0.9963 3118042 ChemDiv3_001782 COc1cccc(c1)N2C(=O)/C(=C/c3ccsc3)/C(=O)NC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A23 mock treatment 374835.0 -332000.0 -0.7 436550.0 -372000.0 -0.85 -1.0958 -0.9959 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 A24 mock treatment 477905.0 -229000.0 -0.49 447591.0 -361000.0 -0.82 -0.9235 -0.9688 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B01 compound treatment 405187.0 -302000.0 -0.64 439293.0 -369000.0 -0.84 -1.0459 -0.9911 1408187 ChemDiv3_001783 Cc1ccc(NC(=O)CSc2nnc(s2)N3C(=O)c4ccccc4C3=O)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B02 compound treatment 578969.0 -128000.0 -0.27 700520.0 -108000.0 -0.25 -0.3654 -0.9987 1465544 ChemDiv3_001784 S=C(Nc1ccccc1)N2CCC(=N2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B03 compound treatment 948892.0 242000.0 0.51 805851.0 -2510.0 -0.01 0.3585 0.6992 3118043 ChemDiv3_001785 Cc1cc(C)c(N2C(=O)NC(=O)/C(=C\Nc3cccc(O)c3)/C2=O)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B04 compound treatment 960306.0 253000.0 0.54 837467.0 29100.0 0.07 0.4264 0.7883 1229641 ChemDiv3_001786 CCOC(=O)C(Cc1ccccc1)C(=O)Nc2nc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B05 compound treatment 1125711.0 419000.0 0.89 899812.0 91400.0 0.21 0.7746 0.8498 3021569 ChemDiv3_001787 CCN1C(=O)C(=Cc2ccc(o2)c3ccccc3F)C(=O)N(CC)C1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B06 compound treatment 1102419.0 395000.0 0.84 955589.0 147000.0 0.33 0.8293 0.9189 1193124 ChemDiv3_001788 Cc1oc2ccc(O)cc2c1C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B07 compound treatment 993856.0 287000.0 0.61 929367.0 121000.0 0.28 0.6244 0.9357 3021570 ChemDiv3_001789 CC(C)(C)N(CCO)C(=O)CN1C(=O)/C(=C/c2cccc(Br)c2)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B08 compound treatment 1071115.0 364000.0 0.77 1064032.0 256000.0 0.58 0.9567 0.9902 1231195 ChemDiv3_001790 COC(=O)COc1cccc2c1ccc3c4CCCCc4c(=O)oc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B09 compound treatment 973899.0 267000.0 0.57 1037254.0 229000.0 0.52 0.768 0.9991 3118044 ChemDiv3_001791 CCCCn1c-2c(CCc3nonc32)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B10 compound treatment 1067384.0 360000.0 0.76 960020.0 152000.0 0.34 0.7839 0.9354 1442608 ChemDiv3_001792 COc1ccc(cc1OC)C2CC(=O)c3cnc(N)nc3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B11 compound treatment 1130312.0 423000.0 0.9 1077290.0 269000.0 0.61 1.0668 0.9825 1122476 ChemDiv3_001793 Clc1ccc(cc1)c2nc(N3CCCCC3)c4ccccc4n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B12 compound treatment 1076915.0 370000.0 0.78 978719.0 170000.0 0.39 0.8283 0.9471 3118045 ChemDiv3_001794 CN1C(=O)/C(=C/2\SC(=S)N(C3CCS(=O)(=O)C3)C2=O)/c4cc(Br)ccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B13 compound treatment 163431.0 -544000.0 -1.15 117998.0 -690000.0 -1.57 -1.9248 -0.9885 1382733 ChemDiv3_001795 Oc1ccc(I)nc1CCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B14 compound treatment 1030364.0 323000.0 0.69 960182.0 152000.0 0.35 0.7287 0.9496 1453546 ChemDiv3_001796 CN(C)c1ccc(cc1)N2C(=O)C3CC(=C(C)CC3C2=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B15 compound treatment 808938.0 102000.0 0.22 856618.0 48300.0 0.11 0.2303 0.9507 1593282 ChemDiv3_001797 COc1ccc2N(C(=O)Nc3ccc(Cl)cc3)C(C)(C)CC(C)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B16 compound treatment 973038.0 266000.0 0.56 965147.0 157000.0 0.36 0.6507 0.9755 3021571 ChemDiv3_001798 CCCCC1(C)OC(=O)C(=Cc2ccc(SC)cc2)C(=O)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B17 compound treatment 941501.0 234000.0 0.5 971047.0 163000.0 0.37 0.613 0.9894 1026532 ChemDiv3_001799 Cc1ccc(cc1)C(=O)N2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B18 compound treatment 423608.0 -283000.0 -0.6 523629.0 -285000.0 -0.65 -0.8827 -0.9993 3021572 ChemDiv3_001800 O=C1C=CC2(CC3(CCCCC3)N=C2SCc4ccccc4)C=C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B19 compound treatment 1075042.0 368000.0 0.78 929206.0 121000.0 0.27 0.7459 0.9018 1698847 ChemDiv3_001801 O=c1n(Cc2ccccc2)c(=S)[nH]c3sc4CCCCCc4c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B20 compound treatment 748531.0 41500.0 0.09 807486.0 -877.0 0.0 0.0607 0.6909 1202827 ChemDiv3_001802 Cc1nc2ccccc2c(=O)n1NCc3ccccc3Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B21 compound treatment 982717.0 276000.0 0.58 900174.0 91800.0 0.21 0.5608 0.9038 1391827 ChemDiv3_001803 CNC(=O)c1c(c2ccccc2)c3cc(OC)ccc3n1CCN(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B22 compound treatment 882043.0 175000.0 0.37 859697.0 51300.0 0.12 0.3448 0.8867 3118046 ChemDiv3_001804 CCOC(=O)c1c(C)oc2ccc(OCC)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B23 mock treatment 511755.0 -195000.0 -0.41 790637.0 -17700.0 -0.04 -0.3213 -0.7723 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 B24 mock treatment 402207.0 -305000.0 -0.65 532112.0 -276000.0 -0.63 -0.9011 -0.9999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C01 compound treatment 377308.0 -330000.0 -0.7 463854.0 -345000.0 -0.78 -1.0482 -0.9984 3118047 ChemDiv3_001805 COc1ccc(cc1OC)C(CC(=O)c2ccco2)Sc3cccc4cccnc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C02 compound treatment 421710.0 -285000.0 -0.6 485096.0 -323000.0 -0.73 -0.9475 -0.9953 1315783 ChemDiv3_001806 Cn1ccnc1SCC(=O)N2c3ccccc3C(C)(CC2(C)C)c4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C03 compound treatment 314899.0 -392000.0 -0.83 371889.0 -436000.0 -0.99 -1.2896 -0.9961 3118179 ChemDiv3_001807 COc1cccc2s/c(=N/C(=O)COc3ccc(Cl)cc3Cl)/n(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C04 compound treatment 840902.0 134000.0 0.28 864502.0 56100.0 0.13 0.2909 0.935 3021573 ChemDiv3_001808 CCOC(=O)CCSc1nc(C)c2ccccc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C05 compound treatment 742525.0 35500.0 0.08 795711.0 -12700.0 -0.03 0.0328 0.4076 1356071 ChemDiv3_001809 CP(=O)(O)c1nccn1c2ccc(Cl)nn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C06 compound treatment 913408.0 206000.0 0.44 871537.0 63200.0 0.14 0.4109 0.8924 3118180 ChemDiv3_001810 COCc1cc(=O)nc(Sc2c(O)nc3cc(Cl)ccc3c2c4ccccc4)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C07 compound treatment 365759.0 -341000.0 -0.72 336162.0 -472000.0 -1.07 -1.2708 -0.9816 3021574 ChemDiv3_001811 Cc1n(C)c2ccccc2[n+]1CC(=O)c3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C08 compound treatment 722677.0 15600.0 0.03 859434.0 51100.0 0.12 0.1055 0.8738 1515483 ChemDiv3_001812 S=C(N1CCCCC1)c2cccc(OCc3ccccc3)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C09 compound treatment 743472.0 36400.0 0.08 796234.0 -12100.0 -0.03 0.0351 0.4279 1633788 ChemDiv3_001813 COc1ccc(cc1OC)C2CC(=O)n3nc(nc3S2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C10 compound treatment 852413.0 145000.0 0.31 920869.0 113000.0 0.26 0.3987 0.9957 3118181 ChemDiv3_001814 C/C(=C\C=C\c1ccccc1)/C(=O)c2c(C)cc(C)[nH]c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C11 compound treatment 646327.0 -60700.0 -0.13 663912.0 -144000.0 -0.33 -0.3233 -0.9164 1558595 ChemDiv3_001815 Cc1ccc2n(CC(O)Cn3c(C)cc(C)nc3=O)c(c(c4ccccc4)c2c1)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C12 compound treatment 673718.0 -33400.0 -0.07 635335.0 -173000.0 -0.39 -0.3282 -0.8211 3021616 ChemDiv3_001816 COC(=O)CN1C(c2ccccc2)c3cc(Cl)ccc3N=C1c4ccc(OC)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C13 compound treatment 885865.0 179000.0 0.38 946556.0 138000.0 0.31 0.4902 0.9957 1164199 ChemDiv3_001817 COc1ccc(CNc2ncn[nH]2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C14 compound treatment 884830.0 178000.0 0.38 713498.0 -94900.0 -0.22 0.114 0.2624 1183780 ChemDiv3_001818 Cc1ccc(cc1C)C(=O)c2cc(F)c(cc2Cl)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C15 compound treatment 923579.0 217000.0 0.46 716033.0 -92300.0 -0.21 0.1761 0.3489 1590710 ChemDiv3_001819 Clc1ccccc1C(=O)NCCc2c[nH]c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C16 compound treatment 917192.0 210000.0 0.45 894608.0 86200.0 0.2 0.4536 0.9321 3118182 ChemDiv3_001820 COc1ccccc1N2C(=O)NC(=O)/C(=C\C=C\c3ccco3)/C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C17 compound treatment 867620.0 161000.0 0.34 878324.0 70000.0 0.16 0.3531 0.94 3021617 ChemDiv3_001821 OC(=O)/C(=C/c1ccc2OCOc2c1)/NC(=O)c3ccccc3Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C18 compound treatment 878398.0 171000.0 0.36 784059.0 -24300.0 -0.06 0.2177 0.5927 3118183 ChemDiv3_001822 Ic1ccc(Nc2nc(Nc3ccccc3)nc(n2)N4CCOCC4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C19 compound treatment 791542.0 84500.0 0.18 713940.0 -94400.0 -0.21 -0.0252 -0.0901 1705372 ChemDiv3_001823 CCn1c2ccccc2c3cc(CN4CCN(Cc5cccc(C)c5)CC4)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C20 compound treatment 1039450.0 332000.0 0.7 968949.0 161000.0 0.37 0.7564 0.9531 1427498 ChemDiv3_001824 Clc1ccc(CN2CCNCC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C21 compound treatment 882047.0 175000.0 0.37 737678.0 -70700.0 -0.16 0.1487 0.3677 1410682 ChemDiv3_001825 CC1CC(Nc2ccccc2)c3ccccc3N1S(=O)(=O)c4ccc(Br)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C22 compound treatment 875359.0 168000.0 0.36 812222.0 3860.0 0.01 0.2585 0.7243 3021618 ChemDiv3_001826 COc1cccc(/C=C/2\C(=O)NC(=O)N(C)C2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C23 mock treatment 693537.0 -13500.0 -0.03 718422.0 -89900.0 -0.2 -0.1649 -0.7985 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 C24 mock treatment 426215.0 -281000.0 -0.6 507236.0 -301000.0 -0.68 -0.9051 -0.9976 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D01 compound treatment 414832.0 -292000.0 -0.62 533662.0 -275000.0 -0.62 -0.8797 -1.0 3021619 ChemDiv3_001827 CCOC(=O)c1nc2ccccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D02 compound treatment 133511.0 -574000.0 -1.22 192369.0 -616000.0 -1.4 -1.8501 -0.9975 1548078 ChemDiv3_001828 O=C(c1c(oc2C(=O)c3ccccc3C(=O)c12)c4ccccc4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D03 compound treatment 763870.0 56800.0 0.12 746601.0 -61800.0 -0.14 -0.0142 -0.0765 3118184 ChemDiv3_001829 Oc1ccc(/C=C/2\C(=O)NC(=O)N(CC=C)C2=O)cc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D04 compound treatment 802729.0 95700.0 0.2 761154.0 -47200.0 -0.11 0.0675 0.2942 1159195 ChemDiv3_001830 O=C(CCC1CCCCC1)Nc2nc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D05 compound treatment 907555.0 200000.0 0.43 827777.0 19400.0 0.04 0.3317 0.7764 3021621 ChemDiv3_001831 Clc1ccc(cc1)c2ccc(=S)n(n2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D06 compound treatment 968680.0 262000.0 0.55 928623.0 120000.0 0.27 0.5855 0.9469 1463047 ChemDiv3_001832 Cc1ccc(OC(=O)c2cc(ccc2C)S(=O)(=O)N3CCCC3)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D07 compound treatment 1044765.0 338000.0 0.72 945234.0 137000.0 0.31 0.7262 0.9304 3021622 ChemDiv3_001833 CCOC(=O)C1C(NC(=S)NC1(O)C(F)(F)F)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D08 compound treatment 1010523.0 303000.0 0.64 997078.0 189000.0 0.43 0.7583 0.9806 1242363 ChemDiv3_001834 CCOC(=O)C(C)Oc1cc2oc(=O)c3CCCCc3c2cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D09 compound treatment 969498.0 262000.0 0.56 1374254.0 566000.0 1.29 1.3031 0.9297 3021623 ChemDiv3_001835 CCOC(=O)c1c(C)n(OCc2ccccc2)c3ccc4nonc4c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D10 compound treatment 702823.0 -4250.0 -0.01 782912.0 -25500.0 -0.06 -0.0473 -0.8075 1388539 ChemDiv3_001836 COc1ccc(cc1)C2CC(=O)C3=C(C2)Nc4ccccc4N(C3c5ccccc5)C(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D11 compound treatment 948176.0 241000.0 0.51 1033121.0 225000.0 0.51 0.7227 1.0 3021624 ChemDiv3_001837 CCOc1nc(nc2ccccc12)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D12 compound treatment 972137.0 265000.0 0.56 1032062.0 224000.0 0.51 0.757 0.9988 3118185 ChemDiv3_001838 Cc1cccn2c(=O)c(/C=C/3\SC(=S)NC3=O)c(NCC=C)nc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D13 compound treatment 776766.0 69700.0 0.15 757401.0 -51000.0 -0.12 0.0225 0.1201 3021625 ChemDiv3_001839 CC1(C)CC(=O)/C(=C/c2ccco2)/CO1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D14 compound treatment 1026013.0 319000.0 0.68 963884.0 156000.0 0.35 0.7281 0.9543 1476666 ChemDiv3_001840 Brc1ccccc1C(=O)Nc2cccc(c2)c3nc4ccccc4c(=O)o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D15 compound treatment 885563.0 178000.0 0.38 987862.0 179000.0 0.41 0.5561 0.9993 3118186 ChemDiv3_001841 CCOc1ccc(Nc2nc(Nc3ccc(OCC)cc3)nc(SC4=NCCS4)n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D16 compound treatment 1044672.0 338000.0 0.72 926565.0 118000.0 0.27 0.6961 0.9105 3021626 ChemDiv3_001842 O=C1OC(OC(=O)C1=Cc2cccc(OCc3ccccc3)c2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D17 compound treatment 1054929.0 348000.0 0.74 912958.0 105000.0 0.24 0.6896 0.89 1107247 ChemDiv3_001843 CC1CCCC(C)N1C(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D18 compound treatment 909647.0 203000.0 0.43 977062.0 169000.0 0.38 0.5749 0.9984 3021627 ChemDiv3_001844 COc1cc2CC(C)(C)N=C(Nc3nc(cs3)c4ccccc4)c2cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D19 compound treatment 1074632.0 368000.0 0.78 1083207.0 275000.0 0.62 0.9928 0.994 3118187 ChemDiv3_001845 CCCCc1nc2ccccc2c(=O)n1c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D20 compound treatment 1150777.0 444000.0 0.94 1111111.0 303000.0 0.69 1.1518 0.9882 1507247 ChemDiv3_001846 Clc1c(sc2ccccc12)C(=O)NCCC3=CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D21 compound treatment 1081210.0 374000.0 0.79 1031065.0 223000.0 0.51 0.9189 0.9765 3021628 ChemDiv3_001847 COC(=O)Cn1c2CCCCc2c3cc(C)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D22 compound treatment 846145.0 139000.0 0.29 711578.0 -96800.0 -0.22 0.0529 0.1437 1488517 ChemDiv3_001848 COC(=O)c1c(C)oc2ccc(OCC#N)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D23 mock treatment 935402.0 228000.0 0.48 960594.0 152000.0 0.35 0.587 0.9865 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 D24 mock treatment 575842.0 -131000.0 -0.28 476094.0 -332000.0 -0.76 -0.7309 -0.9079 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E01 compound treatment 476027.0 -231000.0 -0.49 491660.0 -317000.0 -0.72 -0.8555 -0.9824 1575197 ChemDiv3_001849 O=C(Nc1ccc(cc1)c2nc3ccccc3o2)c4ccc(cc4)C(=O)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E02 compound treatment 659935.0 -47100.0 -0.1 770568.0 -37800.0 -0.09 -0.1314 -0.9972 1324387 ChemDiv3_001850 Cc1ccc(cc1)C(=O)N2C(=O)C(Oc3ccccc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E03 compound treatment 971357.0 264000.0 0.56 931826.0 123000.0 0.28 0.5947 0.9489 3118188 ChemDiv3_001851 COc1cccc2s/c(=N/C(=S)NC(=O)c3ccc(C)cc3)/n(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E04 compound treatment 912124.0 205000.0 0.43 960598.0 152000.0 0.35 0.5521 0.9936 3021629 ChemDiv3_001852 CCOC(=O)CSc1nc(C)c2cc(C)c(C)cc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E05 compound treatment 1051967.0 345000.0 0.73 1087260.0 279000.0 0.63 0.9654 0.9975 1633868 ChemDiv3_001853 O=C(Nc1ccccc1c2nc3ccccc3s2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E06 compound treatment 878452.0 171000.0 0.36 806936.0 -1430.0 0.0 0.2546 0.7008 1479197 ChemDiv3_001854 Oc1nc2cc(Cl)ccc2c(c1SC3=NCCS3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E07 compound treatment 843212.0 136000.0 0.29 800541.0 -7820.0 -0.02 0.1915 0.6623 1403729 ChemDiv3_001855 COc1ccc(cc1)S(=O)(=O)N2Cc3ccccc3CC2C(=O)N4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E08 compound treatment 967468.0 260000.0 0.55 943405.0 135000.0 0.31 0.6074 0.9617 1609478 ChemDiv3_001856 COc1ccc(cc1OC)C(=S)N2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E09 compound treatment 783349.0 76300.0 0.16 779093.0 -29300.0 -0.07 0.0673 0.3848 3118189 ChemDiv3_001857 Cc1ccc(c(C)c1)n2c(C)cc(=O)cc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E10 compound treatment 860725.0 154000.0 0.33 749302.0 -59100.0 -0.13 0.1354 0.3842 1627173 ChemDiv3_001858 OC(=O)CCCC(=O)Nc1cccc2cccnc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E11 compound treatment 1079702.0 373000.0 0.79 973150.0 165000.0 0.37 0.8235 0.9419 3021676 ChemDiv3_001859 Cc1cc(O)nc(SCC(=O)c2cccs2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E12 compound treatment 238368.0 -469000.0 -0.99 214667.0 -594000.0 -1.35 -1.6571 -0.9886 3118190 ChemDiv3_001860 Cc1ccc2[nH]c(=O)c(c(c3ccccc3)c2c1)[n+]4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E13 compound treatment 1036892.0 330000.0 0.7 1112849.0 304000.0 0.69 0.9839 1.0 3118191 ChemDiv3_001861 C/C(=C/1\SC(=S)NC1=O)/C\C(=C/2\SC(=S)NC2=O)\C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E14 compound treatment 1856349.0 1150000.0 2.44 1821387.0 1010000.0 2.3 3.3514 0.9996 1418462 ChemDiv3_001862 O=C(Oc1ccc2ccc(=O)oc2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E15 compound treatment 1020060.0 313000.0 0.66 851776.0 43400.0 0.1 0.539 0.8035 1307975 ChemDiv3_001863 CCOC(=O)c1ccc(Nc2cc(C)nc(n2)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E16 compound treatment 1009211.0 302000.0 0.64 1106791.0 298000.0 0.68 0.9327 0.9996 3021677 ChemDiv3_001864 COc1cccc(/C=C/2\C(=O)NC(=O)N(C2=O)c3cccc(OC)c3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E17 compound treatment 916390.0 209000.0 0.44 1011157.0 203000.0 0.46 0.6398 0.9998 3118326 ChemDiv3_001865 Clc1ccccc1C(=O)N/C(=C\c2ccc3OCOc3c2)/C(=O)N4CCOCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E18 compound treatment 981431.0 274000.0 0.58 813193.0 4830.0 0.01 0.419 0.7203 1535987 ChemDiv3_001866 CC1CCN(Cn2c(=S)n(CN3CCC(C)CC3)c4ccccc24)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E19 compound treatment 1089433.0 382000.0 0.81 1086412.0 278000.0 0.63 1.0202 0.9924 1155262 ChemDiv3_001867 COc1ccccc1CN2CCN(Cc3ccccc3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E20 compound treatment 963142.0 256000.0 0.54 807730.0 -633.0 0.0 0.3828 0.7052 1640740 ChemDiv3_001868 CCCC1=C(C(C(=C(N1)SC)C#N)c2ccccc2Cl)C(=O)OCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E21 compound treatment 923204.0 216000.0 0.46 848350.0 40000.0 0.09 0.3883 0.8312 1272136 ChemDiv3_001869 CC1=CC(C)(C)N(C(=O)CN2C(=O)c3ccccc3C2=O)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E22 compound treatment 756678.0 49600.0 0.11 818115.0 9750.0 0.02 0.09 0.8378 3118327 ChemDiv3_001870 CN1C(=O)NC(=O)/C(=C\c2ccc(O)cc2)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E23 mock treatment 563022.0 -144000.0 -0.31 769464.0 -38900.0 -0.09 -0.2785 -0.8759 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 E24 mock treatment 477446.0 -230000.0 -0.49 578929.0 -229000.0 -0.52 -0.7131 -0.9994 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F01 compound treatment 498560.0 -209000.0 -0.44 514830.0 -294000.0 -0.67 -0.7845 -0.98 1132984 ChemDiv3_001871 COc1ccc(NC(=S)NCC2CCCO2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F02 compound treatment 157376.0 -550000.0 -1.17 157908.0 -650000.0 -1.48 -1.8697 -0.993 3118328 ChemDiv3_001872 O=C1c2oc(c(C#N)c2C(=O)c3ccccc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F03 compound treatment 678502.0 -28600.0 -0.06 1059931.0 252000.0 0.57 0.3616 0.6287 3021678 ChemDiv3_001873 CCN1C(=O)/C(=C/c2ccc[nH]2)/C(=O)NC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F04 compound treatment 593911.0 -113000.0 -0.24 587891.0 -220000.0 -0.5 -0.5241 -0.9431 3118329 ChemDiv3_001874 COc1ccc(cc1OC)C2CC(=NN2)c3cc(Cl)ccc3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F05 compound treatment 646945.0 -60100.0 -0.13 991503.0 183000.0 0.42 0.2043 0.4691 1704441 ChemDiv3_001875 CCSc1ccc(NC(=O)CC2c3ccccc3Oc4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F06 compound treatment 828624.0 122000.0 0.26 1045510.0 237000.0 0.54 0.5635 0.9429 1175553 ChemDiv3_001876 Cc1ccc(cc1S(=O)(=O)N2CCCCC2)C(=O)NCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F07 compound treatment 169974.0 -537000.0 -1.14 168926.0 -639000.0 -1.45 -1.8331 -0.9927 3118330 ChemDiv3_001877 CCCCN(C)Cc1c(O)ccc2c(=O)c(c3ccccc3OC)c(oc12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F08 compound treatment 980453.0 273000.0 0.58 915701.0 107000.0 0.24 0.5824 0.9261 1437891 ChemDiv3_001878 Cc1cn2c(n1)n(Cc3ccc(C)cc3)c4ccccc42 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F09 compound treatment 1169987.0 463000.0 0.98 1320775.0 512000.0 1.16 1.5177 0.9964 3118331 ChemDiv3_001879 [O-][n+]1c(c2ccccc2)c(=O)n(OCc3ccccc3)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F10 compound treatment 1172103.0 465000.0 0.99 1127276.0 319000.0 0.73 1.2098 0.9886 1724763 ChemDiv3_001880 CCNC(=S)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4ccc(cc4)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F11 compound treatment 1146043.0 439000.0 0.93 1563283.0 755000.0 1.72 1.8717 0.9587 1445265 ChemDiv3_001881 C1CCN(C1)c2nc3ccccc3n4cnnc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F12 compound treatment 1096732.0 390000.0 0.83 1651862.0 843000.0 1.92 1.9402 0.9292 1581689 ChemDiv3_001882 Cc1ccc(cc1)c2nnc(Sc3nc4ccccc4o3)c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F13 compound treatment 1317600.0 611000.0 1.29 1598175.0 790000.0 1.8 2.1849 0.9871 1785410 ChemDiv3_001883 CC(C)N1CC2(N3CC4(C)CN2CC(C)(C3)C4=O)c5ccccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F14 compound treatment 1154041.0 447000.0 0.95 1420099.0 612000.0 1.39 1.6535 0.9825 1701789 ChemDiv3_001884 CS(=O)(=O)N(Cc1ccc(Cl)cc1)c2ccc(cc2)C(=O)N3CCCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F15 compound treatment 965727.0 259000.0 0.55 1171359.0 363000.0 0.83 0.9713 0.9803 3118332 ChemDiv3_001885 NC(=N)/N=c/1\[nH]c(=O)c2ccccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F16 compound treatment 1071487.0 364000.0 0.77 1168674.0 360000.0 0.82 1.1255 0.9996 3118333 ChemDiv3_001886 CC(C)(C)C1(C)OC(=O)C(=Cc2ccccc2Cl)C(=O)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F17 compound treatment 1097969.0 391000.0 0.83 1198950.0 391000.0 0.89 1.2139 0.9994 1472344 ChemDiv3_001887 O=C(OCCN1C(=O)c2ccccc2C1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F18 compound treatment 1095988.0 389000.0 0.82 1168460.0 360000.0 0.82 1.1619 1.0 1671379 ChemDiv3_001888 COc1ccc(OC)c2C(=NC(C)(C)Cc12)SC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F19 compound treatment 1249796.0 543000.0 1.15 1076927.0 269000.0 0.61 1.2453 0.9561 3021679 ChemDiv3_001889 CCOC(=O)c1c(C)c2/C(=N/O)/CCCc2n1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F20 compound treatment 1601445.0 894000.0 1.9 1516965.0 709000.0 1.61 2.4799 0.9967 1637847 ChemDiv3_001890 CC(=O)Oc1ccc2cc(c3nc4ccccc4n3C)c(=O)oc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F21 compound treatment 967592.0 261000.0 0.55 1030100.0 222000.0 0.5 0.747 0.999 3021680 ChemDiv3_001891 N#CCc1nnc2CCCCCn12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F22 compound treatment 945167.0 238000.0 0.5 974689.0 166000.0 0.38 0.6243 0.9899 1388136 ChemDiv3_001892 COC(=O)c1c(C)oc2ccc(OCc3ccccc3C)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F23 mock treatment 823819.0 117000.0 0.25 950070.0 142000.0 0.32 0.4028 0.9915 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 F24 mock treatment 578263.0 -129000.0 -0.27 770968.0 -37400.0 -0.09 -0.2532 -0.8853 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G01 compound treatment 631284.0 -75800.0 -0.16 826279.0 17900.0 0.04 -0.0848 -0.5117 3021681 ChemDiv3_001893 Cn1/c(=N/C(=O)c2cccc(c2)C(F)(F)F)/sc3c1ccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G02 compound treatment 834031.0 127000.0 0.27 979822.0 171000.0 0.39 0.466 0.9836 1418652 ChemDiv3_001894 COc1ccc(OCC(=O)N2c3ccccc3Sc4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G03 compound treatment 878805.0 172000.0 0.36 1103031.0 295000.0 0.67 0.7312 0.9589 1381191 ChemDiv3_001895 Nc1c(C(=O)c2ccccc2)n3ccccc3c1c4nc(cs4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G04 compound treatment 1047943.0 341000.0 0.72 1098078.0 290000.0 0.66 0.9767 0.9989 1522414 ChemDiv3_001896 Cc1ccc(SCc2cc(O)nc(Nc3nc4ccccc4o3)n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G05 compound treatment 1055232.0 348000.0 0.74 1011678.0 203000.0 0.46 0.8488 0.9746 1650593 ChemDiv3_001897 CCCCC1CCC(CC1)C(=O)ON2C(=O)c3cccc4cccc(C2=O)c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G06 compound treatment 1211702.0 505000.0 1.07 1133378.0 325000.0 0.74 1.279 0.9837 1442367 ChemDiv3_001898 S=c1[nH]nc(c2cccnc2)n1C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G07 compound treatment 1081594.0 375000.0 0.79 1174583.0 366000.0 0.83 1.1502 0.9997 1200273 ChemDiv3_001899 CC1(C)CC(=O)C2=C(C1)Nc3[nH]c(=S)[nH]c(=O)c3C2c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G08 compound treatment 1041901.0 335000.0 0.71 1145346.0 337000.0 0.77 1.0437 0.9993 3020977 ChemDiv3_001900 Clc1ccc(cc1)C(=S)N2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G09 compound treatment 1215957.0 509000.0 1.08 1239343.0 431000.0 0.98 1.4557 0.9988 3020978 ChemDiv3_001901 CCCCn1c(nc(=S)c2CCCCc21)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G10 compound treatment 1327524.0 620000.0 1.32 1471443.0 663000.0 1.51 1.9961 0.9977 1183988 ChemDiv3_001902 CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)NCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G11 compound treatment 1285445.0 578000.0 1.23 1772300.0 964000.0 2.19 2.4167 0.9623 3020979 ChemDiv3_001903 Nc1cc(O)nc(SCC(=O)c2cccs2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G12 compound treatment 1491699.0 785000.0 1.66 1639149.0 831000.0 1.89 2.5118 0.998 1644588 ChemDiv3_001904 CCCc1c(O)nc(SCc2ccccc2)[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G13 compound treatment 1690246.0 983000.0 2.08 1505010.0 697000.0 1.58 2.5938 0.9908 3118334 ChemDiv3_001905 C/N=C(\c1ccc(C)cc1)/n2c(=S)nc(c3ccc(C)cc3)n(C)c2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G14 compound treatment 1334734.0 628000.0 1.33 1698252.0 890000.0 2.02 2.3715 0.9793 3020980 ChemDiv3_001906 CCC(=O)NC(Nc1cccnc1Cl)(C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G15 compound treatment 1635273.0 928000.0 1.97 1577761.0 769000.0 1.75 2.6283 0.9983 1404360 ChemDiv3_001907 Cc1sc(NC(=O)C(Cc2ccccc2)Cc3ccccc3)c(C#N)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G16 compound treatment 1265106.0 558000.0 1.18 1637825.0 829000.0 1.89 2.17 0.9748 1312332 ChemDiv3_001908 Cc1ccc(NC(=O)c2cc3ccccc3oc2=N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G17 compound treatment 1329600.0 623000.0 1.32 1204540.0 396000.0 0.9 1.5701 0.9827 3118335 ChemDiv3_001909 COc1ccccc1C(=O)N/C(=C\c2ccccc2)/C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G18 compound treatment 1658820.0 952000.0 2.02 1375698.0 567000.0 1.29 2.3388 0.9766 1265569 ChemDiv3_001910 CC1(C)C(C(=O)N2CCN(CC2)c3ccc(Cl)cc3)C1(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G19 compound treatment 146456.0 -561000.0 -1.19 152500.0 -656000.0 -1.49 -1.8948 -0.9937 1567377 ChemDiv3_001911 COc1ccc(CNC2C3CC4CC(C3)CC2C4)c(OC)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G20 compound treatment 1209902.0 503000.0 1.07 954285.0 146000.0 0.33 0.9883 0.8853 1616500 ChemDiv3_001912 CC(C)OC(=O)CSC1=C(C#N)C(CC(=O)N1)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G21 compound treatment 1085492.0 378000.0 0.8 1005329.0 197000.0 0.45 0.8839 0.9621 1342244 ChemDiv3_001913 O=C(CN1C(=O)c2ccccc2C1=O)N3c4ccccc4Sc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G22 compound treatment 1062493.0 355000.0 0.75 1001457.0 193000.0 0.44 0.8432 0.9669 3020981 ChemDiv3_001914 Cc1ccc(cc1)c2nc(no2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G23 mock treatment 975516.0 268000.0 0.57 938501.0 130000.0 0.3 0.6116 0.9536 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 G24 mock treatment 496700.0 -210000.0 -0.45 863374.0 55000.0 0.13 -0.2269 -0.4899 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H01 compound treatment 587779.0 -119000.0 -0.25 659451.0 -149000.0 -0.34 -0.4182 -0.9897 1224823 ChemDiv3_001915 CC(Oc1ccc(Cl)c(C)c1)C(=O)Nc2sc3CCCCCCc3c2C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H02 compound treatment 591898.0 -115000.0 -0.24 682880.0 -125000.0 -0.29 -0.3744 -0.997 1608454 ChemDiv3_001916 O=C1OC(Oc2cccc3cccnc23)(c4ccccc14)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H03 compound treatment 826336.0 119000.0 0.25 1031658.0 223000.0 0.51 0.5378 0.9482 3020982 ChemDiv3_001917 CCc1n[nH]c2OC(=C(C#N)C(c12)c3cccc(OC(=O)N4CCOCC4)c3)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H04 compound treatment 762233.0 55200.0 0.12 968751.0 160000.0 0.36 0.3405 0.8893 1208340 ChemDiv3_001918 N(c1ccc2ccccc2c1)c3ncnc4[nH]ncc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H05 compound treatment 861564.0 154000.0 0.33 1187672.0 379000.0 0.86 0.8414 0.9121 3118467 ChemDiv3_001919 Clc1ccccc1OCCNC(=O)CC2c3ccccc3Oc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H06 compound treatment 1034416.0 327000.0 0.69 1131252.0 323000.0 0.73 1.0098 0.9996 1533326 ChemDiv3_001920 OC(=O)c1cccc(NC(=O)c2cccc(c2)S(=O)(=O)N3CCCCC3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H07 compound treatment 1034368.0 327000.0 0.69 1294913.0 487000.0 1.11 1.2728 0.9748 3118468 ChemDiv3_001921 COC(=O)CN1C(=O)/C(=C\c2ccc(O)cc2)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H08 compound treatment 1015785.0 309000.0 0.65 1326697.0 518000.0 1.18 1.2961 0.9615 3118469 ChemDiv3_001922 CC(C)CCOc1ccc(/C=N/c2nc3ccccc3n2CC=C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H09 compound treatment 1165263.0 458000.0 0.97 1303288.0 495000.0 1.13 1.4825 0.9973 1416640 ChemDiv3_001923 CCOn1c(=O)c(=O)n(OC)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H10 compound treatment 1335160.0 628000.0 1.33 1829757.0 1020000.0 2.32 2.5836 0.9652 3020983 ChemDiv3_001924 O=C1C(=CNCCN2CCOCC2)C(=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H11 compound treatment 1422493.0 715000.0 1.52 1668523.0 860000.0 1.96 2.4553 0.9921 3118470 ChemDiv3_001925 C(Nc1ccccc1)C2OCc3ccccc3CO2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H12 compound treatment 1469648.0 763000.0 1.62 2409782.0 1600000.0 3.64 3.7176 0.9332 1432963 ChemDiv3_001926 COc1ccc(cc1)c2nnc(Nc3ccc(Cl)cc3)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H13 compound treatment 1186611.0 480000.0 1.02 1514303.0 706000.0 1.6 1.8537 0.9757 3020985 ChemDiv3_001927 Oc1ccc(/C=N/CC2OCCc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H14 compound treatment 1338324.0 631000.0 1.34 1599459.0 791000.0 1.8 2.2181 0.9894 1651658 ChemDiv3_001928 CS(=O)(=O)N(CC(=O)NCc1ccco1)c2ccccc2Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H15 compound treatment 1564206.0 857000.0 1.82 1469627.0 661000.0 1.5 2.3479 0.9956 3020986 ChemDiv3_001929 CC(=O)/N=C(/Nc1cc(C)cc(C)c1)\Nc2nc(C)cc(C)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H16 compound treatment 1183566.0 476000.0 1.01 1888835.0 1080000.0 2.46 2.4513 0.9229 3118471 ChemDiv3_001930 CCOc1ccc(C=C2C(=O)OC(OC2=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H17 compound treatment 1001277.0 294000.0 0.62 1231399.0 423000.0 0.96 1.1211 0.978 1104705 ChemDiv3_001931 OC(=O)c1ccc2[n+]([O-])onc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H18 compound treatment 1358767.0 652000.0 1.38 1563082.0 755000.0 1.72 2.1902 0.9942 1710057 ChemDiv3_001932 COc1ccc(OC)c2-c3nnc(c4ccc(Cl)cc4)n3C(C)(C)Cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H19 compound treatment 1408032.0 701000.0 1.49 1302931.0 495000.0 1.12 1.8458 0.9905 1559608 ChemDiv3_001933 CCOC(=O)c1c(C)sc2c3CCCCc3[nH]c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H20 compound treatment 1285576.0 579000.0 1.23 1145116.0 337000.0 0.77 1.4086 0.9743 1736634 ChemDiv3_001934 CCc1cc2c(=O)c(coc2cc1OC(=O)C)c3nc4ccccc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H21 compound treatment 1086251.0 379000.0 0.8 1084647.0 276000.0 0.63 1.0126 0.9926 1604867 ChemDiv3_001935 O=c1cc(Nc2ccccc2)cc[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H22 compound treatment 906476.0 199000.0 0.42 973919.0 166000.0 0.38 0.5651 0.9983 1199255 ChemDiv3_001936 CC(C)OC(=O)c1c(C)oc2cc(Br)c(OC(=O)c3ccco3)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H23 mock treatment 1048374.0 341000.0 0.72 1209994.0 402000.0 0.91 1.1573 0.9934 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 H24 mock treatment 780455.0 73400.0 0.16 910602.0 102000.0 0.23 0.2744 0.9809 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I01 compound treatment 848379.0 141000.0 0.3 754118.0 -54200.0 -0.12 0.1246 0.3847 3020987 ChemDiv3_001937 CCN(CC)c1ccc(cc1)C(=O)/N=c/2\sc3c(ccc4ccccc34)n2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I02 compound treatment 1039607.0 333000.0 0.7 968080.0 160000.0 0.36 0.7552 0.9524 3118472 ChemDiv3_001938 COc1ccccc1C(=O)/N=C(\N)/Nc2nc3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I03 compound treatment 210203.0 -497000.0 -1.05 299057.0 -509000.0 -1.16 -1.5636 -0.9989 1156027 ChemDiv3_001939 CC1CCN(CC(O)COc2ccc(C)cc2C)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I04 compound treatment 1150723.0 444000.0 0.94 1142674.0 334000.0 0.76 1.2025 0.9944 3020988 ChemDiv3_001940 Cc1ccc(cc1)C(=O)/N=C(\N)/Nc2nc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I05 compound treatment 1022554.0 315000.0 0.67 1047327.0 239000.0 0.54 0.8571 0.9947 1061384 ChemDiv3_001941 CCOC(=O)c1c2C(=O)c3ccccc3C(=O)c2n4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I06 compound treatment 1412638.0 706000.0 1.5 1584819.0 776000.0 1.77 2.3059 0.9966 1323512 ChemDiv3_001942 O=C(NC(Cc1ccccc1)C(=O)OCc2cnc(o2)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I07 compound treatment 1012994.0 306000.0 0.65 1116352.0 308000.0 0.7 0.9537 0.9993 3020989 ChemDiv3_001943 CC1(C)C/C(=N\O)/c2c(C1)nc(c3[nH]c4ccccc4c23)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I08 compound treatment 1188951.0 482000.0 1.02 1316619.0 508000.0 1.16 1.5394 0.9981 3020990 ChemDiv3_001944 Oc1ccc(cc1)C(=S)N2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I09 compound treatment 865068.0 158000.0 0.33 862731.0 54400.0 0.12 0.3242 0.9082 3118473 ChemDiv3_001945 CCN(CC)c1ccc(/C=N/CCc2ccccc2)c(O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I10 compound treatment 1381490.0 674000.0 1.43 1689281.0 881000.0 2.0 2.4272 0.9863 1727202 ChemDiv3_001946 CCOC(=O)CSc1nc2CCCCc2cc1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I11 compound treatment 1330338.0 623000.0 1.32 1475335.0 667000.0 1.52 2.0065 0.9976 1682537 ChemDiv3_001947 Cc1ccc(cc1)S(=O)(=O)N2N=C(CC2c3ccc(Cl)cc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I12 compound treatment 1371135.0 664000.0 1.41 1978795.0 1170000.0 2.66 2.8771 0.9557 1023355 ChemDiv3_001948 O=C1NC(=S)NC(=O)C1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I13 compound treatment 1467611.0 761000.0 1.61 1066713.0 258000.0 0.59 1.5554 0.9064 3118474 ChemDiv3_001949 O/N=C(/CC1(O)C(=O)Nc2ccccc21)\c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I14 compound treatment 1570739.0 864000.0 1.83 1936480.0 1130000.0 2.56 3.1083 0.9863 1292612 ChemDiv3_001950 CC(C)(C)NC(=O)CSc1nc2ccccc2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I15 compound treatment 657432.0 -49600.0 -0.11 687842.0 -121000.0 -0.27 -0.2682 -0.9136 1268842 ChemDiv3_001951 COc1ccc(CN(CCC(c2ccc3OCOc3c2)c4ccccc4OC)C(=O)c5ccco5)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I16 compound treatment 1644116.0 937000.0 1.99 1510265.0 702000.0 1.6 2.5331 0.9941 3021034 ChemDiv3_001952 COC(=O)c1c(NC(=S)NC(=O)c2ccccc2)sc3CCCCc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I17 compound treatment 1358069.0 651000.0 1.38 1581637.0 773000.0 1.76 2.219 0.9928 3118475 ChemDiv3_001953 COc1ccccc1C(=O)N/C(=C\c2ccccc2)/C(=O)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I18 compound treatment 1117287.0 410000.0 0.87 1636405.0 828000.0 1.88 1.9461 0.9385 1441672 ChemDiv3_001954 O=C(NC1CCCCCC1)c2ccc3OCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I19 compound treatment 1196750.0 490000.0 1.04 1288150.0 480000.0 1.09 1.5054 0.9997 1243149 ChemDiv3_001955 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)c3csc(n3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I20 compound treatment 1298889.0 592000.0 1.25 1157955.0 350000.0 0.79 1.4492 0.9757 3021035 ChemDiv3_001956 Cn1cccc1/C=C/2\C(=O)NC(=S)N(C2=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I21 compound treatment 1026119.0 319000.0 0.68 1018787.0 210000.0 0.48 0.8165 0.9856 3118476 ChemDiv3_001957 FC(F)(F)c1ccc2Sc3ccccc3N(c2c1)S(=O)(=O)c4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I22 compound treatment 910255.0 203000.0 0.43 1103990.0 296000.0 0.67 0.7798 0.9769 1013814 ChemDiv3_001958 O=C(N1CN(CN(C1)C(=O)c2ccccc2)C(=O)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I23 mock treatment 1016331.0 309000.0 0.66 1308879.0 501000.0 1.14 1.2682 0.9657 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 I24 mock treatment 1016970.0 310000.0 0.66 960859.0 152000.0 0.35 0.7097 0.9554 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J01 compound treatment 793311.0 86200.0 0.18 797514.0 -10800.0 -0.02 0.1118 0.6062 3021036 ChemDiv3_001959 CCC(C)NC=C1C(=O)NC(=O)NC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J02 compound treatment 804664.0 97600.0 0.21 931726.0 123000.0 0.28 0.3446 0.9888 3118477 ChemDiv3_001960 CCOC(=O)C(C1CCCCC1)C(=O)Nc2ccc(Br)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J03 compound treatment 1027438.0 320000.0 0.68 1416556.0 608000.0 1.38 1.458 0.9464 3021037 ChemDiv3_001961 COc1ccc(cc1OC)/C(=C/c2ccc3OCOc3c2)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J04 compound treatment 1099706.0 393000.0 0.83 1416816.0 608000.0 1.38 1.5667 0.9704 1193383 ChemDiv3_001962 Cc1cccc(c1)n2ncc3c(Nc4ccc(cc4)c5ccccc5)ncnc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J05 compound treatment 1199221.0 492000.0 1.04 1199752.0 391000.0 0.89 1.367 0.9969 3118478 ChemDiv3_001963 CC1(C)CC(=C(C2C3=C(CC(C)(C)CC3=O)Oc4ccc(Br)cc24)C(=O)C1)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J06 compound treatment 1280937.0 574000.0 1.22 1104538.0 296000.0 0.67 1.3364 0.9611 1079134 ChemDiv3_001964 OC1(CC(=O)CC2(O)C(=O)Nc3ccccc32)C(=O)Nc4ccccc41 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J07 compound treatment 1173865.0 467000.0 0.99 1401599.0 593000.0 1.35 1.6534 0.9884 3021006 ChemDiv3_001965 COC(=O)CN1C(=O)/C(=C/c2ccc(cc2)N(C)C)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J08 compound treatment 1068871.0 362000.0 0.77 1397822.0 589000.0 1.34 1.49 0.9649 3021008 ChemDiv3_001966 COc1ccc(/C=N/c2nc3ccccc3n2C)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J09 compound treatment 1172731.0 466000.0 0.99 1521909.0 714000.0 1.62 1.8452 0.9716 3118479 ChemDiv3_001967 CC1(C)NC(=[N+]([O-])C1(C)O)C(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J10 compound treatment 1143601.0 437000.0 0.93 1592850.0 784000.0 1.78 1.9155 0.9533 3118608 ChemDiv3_001968 O=C1C(=CNCCc2c[nH]c3ccccc23)C(=O)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J11 compound treatment 1728390.0 1020000.0 2.17 1497986.0 690000.0 1.57 2.6397 0.9874 3021012 ChemDiv3_001969 CCN(CC)c1nc(Cl)nc(n1)N(C)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J12 compound treatment 293375.0 -414000.0 -0.88 349398.0 -459000.0 -1.04 -1.358 -0.9963 1214793 ChemDiv3_001970 Cc1ccccc1Nc2nnc(c3ccc(cc3)C(=O)NCCO)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J13 compound treatment 184469.0 -523000.0 -1.11 186709.0 -622000.0 -1.41 -1.7828 -0.9927 1120090 ChemDiv3_001971 CCc1ccc(NC2=CC(=O)CC(C2)c3ccco3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J14 compound treatment 1240902.0 534000.0 1.13 1472289.0 664000.0 1.51 1.8676 0.9899 1659923 ChemDiv3_001972 O=C(NCc1ccccc1)c2ccc(CN3CCC(Cc4ccccc4)CC3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J15 compound treatment 115725.0 -591000.0 -1.25 115186.0 -693000.0 -1.58 -2.0008 -0.9936 1418748 ChemDiv3_001973 CC(=O)NC(c1ccccc1)c2ccc3cccnc3c2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J16 compound treatment 1570244.0 863000.0 1.83 1820197.0 1010000.0 2.3 2.9206 0.9936 1553968 ChemDiv3_001974 COc1cc(OC)cc(c1)C(=O)Nc2cccc3nsnc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J17 compound treatment 1298824.0 592000.0 1.25 1332277.0 524000.0 1.19 1.7293 0.9997 1597222 ChemDiv3_001975 CN(C)c1ccc(cc1)C(=S)N2CCN(CC2)c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J18 compound treatment 1447132.0 740000.0 1.57 1416016.0 608000.0 1.38 2.0863 0.998 1631516 ChemDiv3_001976 COC(=O)Cn1c(SCc2ccccc2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J19 compound treatment 1277904.0 571000.0 1.21 1211676.0 403000.0 0.92 1.5041 0.9906 1261544 ChemDiv3_001977 CCn1c2C(=O)CCCc2c3cc(ccc13)C4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J20 compound treatment 1236205.0 529000.0 1.12 1319827.0 511000.0 1.16 1.6154 0.9998 1370635 ChemDiv3_001978 O=C(Oc1ccc2cc(c3nc4ccccc4s3)c(=O)oc2c1)c5ccco5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J21 compound treatment 1038805.0 332000.0 0.7 1137239.0 329000.0 0.75 1.026 0.9995 1921265 ChemDiv3_001979 CC(=O)n1c(C)c(c2ccccc2)c3cc(Cl)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J22 compound treatment 986053.0 279000.0 0.59 1149394.0 341000.0 0.78 0.9665 0.9911 1050374 ChemDiv3_001980 O=C1NC(=S)NC(=O)C1=Cc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J23 mock treatment 937231.0 230000.0 0.49 1179885.0 372000.0 0.84 0.9423 0.966 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 J24 mock treatment 1112672.0 406000.0 0.86 1147707.0 339000.0 0.77 1.1535 0.9985 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K01 compound treatment 677966.0 -29100.0 -0.06 674196.0 -134000.0 -0.31 -0.2593 -0.8333 1285843 ChemDiv3_001981 COC(=O)c1sc2ccccc2c1NC(=O)c3ccc(cc3)S(=O)(=O)N(C)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K02 compound treatment 538037.0 -169000.0 -0.36 495935.0 -312000.0 -0.71 -0.7557 -0.9498 1506924 ChemDiv3_001982 COc1ccc(OCC(=O)N2c3ccccc3C(C)(CC2(C)C)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K03 compound treatment 254932.0 -452000.0 -0.96 226780.0 -582000.0 -1.32 -1.6128 -0.9875 1117809 ChemDiv3_001983 CC1CCCC(C)N1CC(O)COc2ccc(C)cc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K04 compound treatment 1102903.0 396000.0 0.84 1026914.0 219000.0 0.5 0.9447 0.9687 3118609 ChemDiv3_001984 COc1ccc(/C=C/C(=O)N2c3ccccc3Sc4ccccc24)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K05 compound treatment 1059191.0 352000.0 0.75 998850.0 190000.0 0.43 0.8341 0.9665 1720319 ChemDiv3_001985 CCOC(=O)N1CCN(CC(O)COc2c(OC)cccc2OC)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K06 compound treatment 1185406.0 478000.0 1.01 1211647.0 403000.0 0.92 1.3654 0.9987 1677632 ChemDiv3_001986 O=C(Oc1ccc(cc1)C(=S)N2CCCCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K07 compound treatment 1094853.0 388000.0 0.82 1163591.0 355000.0 0.81 1.1524 1.0 1191436 ChemDiv3_001987 O=C(CCN1C(=O)c2ccccc2C1=O)N(C3CCCCC3)C4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K08 compound treatment 1231651.0 525000.0 1.11 1222464.0 414000.0 0.94 1.4521 0.9966 3021061 ChemDiv3_001988 O=C(Oc1ccccc1)c2ccc(=O)oc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K09 compound treatment 1087133.0 380000.0 0.81 1131417.0 323000.0 0.73 1.0891 0.9989 1177858 ChemDiv3_001989 O=S(=O)(N(Cc1ccccc1)Cc2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K10 compound treatment 1256572.0 549000.0 1.16 1261475.0 453000.0 1.03 1.5522 0.9981 1319852 ChemDiv3_001990 CCC(=O)Nc1cc2c(C)cc(=O)oc2cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K11 compound treatment 1005732.0 299000.0 0.63 1648335.0 840000.0 1.91 1.7981 0.8937 1184848 ChemDiv3_001991 Cc1ccc(cc1)S(=O)(=O)NCCC(=O)N2CCOCCOCCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K12 compound treatment 1199585.0 493000.0 1.04 1638356.0 830000.0 1.89 2.0726 0.961 1733832 ChemDiv3_001992 CC(=C)c1cccc(c1)C(C)(C)NC(=O)Nc2ccc3c(c2)oc4ccccc43 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K13 compound treatment 1297781.0 591000.0 1.25 1649596.0 841000.0 1.91 2.2379 0.9789 3021100 ChemDiv3_001993 C1CC(SC(C1)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K14 compound treatment 1148335.0 441000.0 0.94 1353701.0 545000.0 1.24 1.5382 0.9904 3118610 ChemDiv3_001994 Cc1ccccc1N2C(=O)NC(=O)/C(=C\C=C\c3ccco3)/C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K15 compound treatment 1219377.0 512000.0 1.09 1302030.0 494000.0 1.12 1.5616 0.9999 1633163 ChemDiv3_001995 O=C(NN1C(=O)C2C3CC(C=C3)C2C1=O)c4ccncc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K16 compound treatment 1197580.0 491000.0 1.04 1335244.0 527000.0 1.2 1.5823 0.9975 1547041 ChemDiv3_001996 OC(=O)c1ccc(Nc2ccnc3cc(Cl)ccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K17 compound treatment 717784.0 10700.0 0.02 628979.0 -179000.0 -0.41 -0.2723 -0.6667 1254558 ChemDiv3_001997 CCn1c2ccccc2c3cc(CN4CCN(CC4)C(=O)c5c(OC)cccc5OC)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K18 compound treatment 1266919.0 560000.0 1.19 1111853.0 303000.0 0.69 1.3271 0.9667 3021103 ChemDiv3_001998 N#Cc1ccc(CSc2nc3ccccc3s2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K19 compound treatment 1092596.0 386000.0 0.82 998317.0 190000.0 0.43 0.8833 0.9555 1375332 ChemDiv3_001999 COc1ccccc1C(=O)Nc2cccc(c2)c3csc(n3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K20 compound treatment 1243581.0 537000.0 1.14 1017881.0 210000.0 0.48 1.1411 0.9254 3118611 ChemDiv3_002000 O=C/1NC(=S)N(C(=O)\C1=C\C=C\c2ccco2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K21 compound treatment 980347.0 273000.0 0.58 1080679.0 272000.0 0.62 0.8474 0.9994 1417257 ChemDiv3_002001 O=C(CSc1nc2ccccc2s1)n3c4ccccc4c5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K22 compound treatment 1061829.0 355000.0 0.75 1049362.0 241000.0 0.55 0.9192 0.9879 1162359 ChemDiv3_002002 CC(=O)Nc1cccc(Oc2ccc3C(=O)N(C(=O)c3c2)c4cccc(Cl)c4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K23 mock treatment 868031.0 161000.0 0.34 930102.0 122000.0 0.28 0.437 0.9946 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 K24 mock treatment 566743.0 -140000.0 -0.3 798336.0 -10000.0 -0.02 -0.2265 -0.7591 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L01 compound treatment 590508.0 -117000.0 -0.25 732820.0 -75500.0 -0.17 -0.2962 -0.9842 3118612 ChemDiv3_002003 Cc1ccccc1N2C(=O)NC(=O)/C(=C\Nc3nccs3)/C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L02 compound treatment 554031.0 -153000.0 -0.32 751848.0 -56500.0 -0.13 -0.3203 -0.9178 3021107 ChemDiv3_002004 CCOC(=O)C(C1CCCCC1)C(=O)Nc2cccc(c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L03 compound treatment 1122997.0 416000.0 0.88 1203028.0 395000.0 0.9 1.258 1.0 3118613 ChemDiv3_002005 Cc1cc(nc(SCC(=O)NCc2cccc(c2)C(F)(F)F)n1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L04 compound treatment 1148870.0 442000.0 0.94 911728.0 103000.0 0.24 0.8284 0.8579 1175222 ChemDiv3_002006 C(c1ccccc1)n2ncc3c(Nc4ccc5ccccc5c4)ncnc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L05 compound treatment 533552.0 -174000.0 -0.37 605660.0 -203000.0 -0.46 -0.586 -0.9938 1331687 ChemDiv3_002007 CC1(C)CC(=O)C2=C(C1)c3c(NC2C4CCC=CC4)ccc5ncccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L06 compound treatment 1146624.0 440000.0 0.93 1223917.0 416000.0 0.94 1.327 1.0 1043898 ChemDiv3_002008 CN(C)Cc1ccc(O)c(CN(C)C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L07 compound treatment 1022402.0 315000.0 0.67 1276044.0 468000.0 1.06 1.2246 0.975 3118614 ChemDiv3_002009 COC(=O)CN1C(=O)/C(=C/c2ccc(OCc3ccccc3)c(OC)c2)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L08 compound treatment 1042153.0 335000.0 0.71 1177840.0 369000.0 0.84 1.0963 0.9965 3021145 ChemDiv3_002010 CN(C)c1ccc(/C=N/c2nc3ccccc3n2Cc4ccc(Cl)cc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L09 compound treatment 1006150.0 299000.0 0.63 1252961.0 445000.0 1.01 1.1631 0.9748 3118615 ChemDiv3_002011 CC12CCCCC2(O)[N+](=C(N1)C(=O)c3ccccc3)[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L10 compound treatment 1095751.0 389000.0 0.82 1197543.0 389000.0 0.88 1.2083 0.9994 3021148 ChemDiv3_002012 Cc1ccsc1/C=C(\C#N)/S(=O)(=O)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L11 compound treatment 1051643.0 345000.0 0.73 1401649.0 593000.0 1.35 1.4703 0.9585 1334871 ChemDiv3_002013 CCOC(=O)CSc1nc(NC#N)nc(n1)N(CC)CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L12 compound treatment 1060144.0 353000.0 0.75 1459919.0 652000.0 1.48 1.5767 0.95 1265403 ChemDiv3_002014 COc1ccc(cc1OC)C(=O)c2nc3ccccc3n2C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L13 compound treatment 543974.0 -163000.0 -0.35 631227.0 -177000.0 -0.4 -0.5293 -0.9971 1205179 ChemDiv3_002015 O=C1CC(CC(=C1)NCCc2ccccc2)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L14 compound treatment 1281117.0 574000.0 1.22 1346474.0 538000.0 1.22 1.7256 1.0 3021152 ChemDiv3_002016 O=C1OC(OC(=O)C1=C/C=C/c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L15 compound treatment 756619.0 49500.0 0.11 924404.0 116000.0 0.26 0.2608 0.9185 1493360 ChemDiv3_002017 CCC(=O)NC(c1ccco1)c2c(OC(=O)C)ccc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L16 compound treatment 1125146.0 418000.0 0.89 1183265.0 375000.0 0.85 1.2294 0.9998 1179677 ChemDiv3_002018 CC(C)(C)c1ccc(OCC(=O)Nc2cccc3nsnc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L17 compound treatment 1092864.0 386000.0 0.82 1172094.0 364000.0 0.83 1.1631 1.0 3118616 ChemDiv3_002019 COc1ccccc1OCCn2cc(/C=C\3/SC(=S)NC3=O)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L18 compound treatment 1316571.0 609000.0 1.29 1250254.0 442000.0 1.0 1.6241 0.9923 1728260 ChemDiv3_002020 O=C1c2ccccc2-c3nc(cc4cccc1c34)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L19 compound treatment 998603.0 292000.0 0.62 1067953.0 260000.0 0.59 0.8543 0.9997 1780366 ChemDiv3_002021 CCOC(=O)CCn1cc(F)c(=O)[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L20 compound treatment 974591.0 268000.0 0.57 1042432.0 234000.0 0.53 0.7773 0.9995 1567440 ChemDiv3_002022 CCOC(=O)COc1cc2oc(C)c(c3nc4ccccc4s3)c(=O)c2cc1CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L21 compound treatment 1128495.0 421000.0 0.89 1157054.0 349000.0 0.79 1.1923 0.9982 1579324 ChemDiv3_002023 COC(=O)c1c(N)c(C#N)c2CCCn12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L22 compound treatment 1049532.0 342000.0 0.73 969780.0 161000.0 0.37 0.7729 0.9501 3118756 ChemDiv3_002024 Cc1ccc(C=C2C(=O)NC(=O)NC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L23 mock treatment 780541.0 73500.0 0.16 904574.0 96200.0 0.22 0.2648 0.9861 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 L24 mock treatment 612382.0 -94700.0 -0.2 721992.0 -86400.0 -0.2 -0.2808 -0.9999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M01 compound treatment 607755.0 -99300.0 -0.21 593977.0 -214000.0 -0.49 -0.4935 -0.9295 1553903 ChemDiv3_002025 COC(=O)c1ccc(cc1)C(=O)NC(=S)Nc2nc3CCCCc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M02 compound treatment 1079489.0 372000.0 0.79 940990.0 133000.0 0.3 0.7715 0.9129 1287477 ChemDiv3_002026 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2c3ccccc3CCc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M03 compound treatment 250162.0 -457000.0 -0.97 237405.0 -571000.0 -1.3 -1.6028 -0.9896 1572495 ChemDiv3_002027 Cc1cc(OCC(O)CNC(C)(C)C)ccc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M04 compound treatment 934831.0 228000.0 0.48 1014736.0 206000.0 0.47 0.6732 0.9999 3021223 ChemDiv3_002028 Cc1ccc(SCc2cc(O)nc(Nc3nc(C)c4ccccc4n3)n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M05 compound treatment 913184.0 206000.0 0.44 947633.0 139000.0 0.32 0.5329 0.9875 3118757 ChemDiv3_002029 CCN(CC)/C(=N/S(=O)(=O)c1ccc(Cl)cc1)/c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M06 compound treatment 1069328.0 362000.0 0.77 1073343.0 265000.0 0.6 0.969 0.9928 1719295 ChemDiv3_002030 O=C(Oc1ccccc1C(=S)N2CCOCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M07 compound treatment 960987.0 254000.0 0.54 1020394.0 212000.0 0.48 0.7215 0.9985 1588037 ChemDiv3_002031 COc1ccc(cc1)n2c(SCC(=O)c3ccc(Cl)cc3)nc4ccccc4c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M08 compound treatment 1333671.0 627000.0 1.33 1820825.0 1010000.0 2.3 2.567 0.9659 1217270 ChemDiv3_002032 CC(=O)Nc1cc2c(ccc3ccccc32)oc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M09 compound treatment 359423.0 -348000.0 -0.74 351434.0 -457000.0 -1.04 -1.2557 -0.9859 1402210 ChemDiv3_002033 COc1ccc(cc1)c2cc3ccccc3n2CC(O)CN(CC=C)CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M10 compound treatment 1022279.0 315000.0 0.67 1108910.0 301000.0 0.68 0.9557 0.9999 1306235 ChemDiv3_002034 CC(=O)Nc1cc2nc(N)sc2cc1NC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M11 compound treatment 971779.0 265000.0 0.56 1148031.0 340000.0 0.77 0.9429 0.9877 3118758 ChemDiv3_002035 COc1ccc(/C=N/c2nc3ccccc3n2CCN4CCCCC4)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M12 compound treatment 1274523.0 567000.0 1.2 1428531.0 620000.0 1.41 1.8476 0.9969 3021285 ChemDiv3_002036 CCOC(=O)c1sc(c(C#N)c1C)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M13 compound treatment 1041806.0 335000.0 0.71 1167549.0 359000.0 0.82 1.0792 0.9976 1367535 ChemDiv3_002037 Brc1ccc(cc1)C(=O)NCC2OCCc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M14 compound treatment 956450.0 249000.0 0.53 1162543.0 354000.0 0.81 0.9432 0.9792 3118759 ChemDiv3_002038 CN1C(=O)NC(=O)/C(=C\C=C\c2ccco2)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M15 compound treatment 922990.0 216000.0 0.46 1244587.0 436000.0 0.99 1.025 0.9383 1234318 ChemDiv3_002039 CCOC(=O)c1c(NC(=S)NCC=C)sc2CCCCCc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M16 compound treatment 884832.0 178000.0 0.38 1082200.0 274000.0 0.62 0.7067 0.9711 1416446 ChemDiv3_002040 O=C1C2C3CC(C=C3)C2C(=O)N1CN4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M17 compound treatment 1109768.0 403000.0 0.85 1169887.0 362000.0 0.82 1.1849 0.9998 1311577 ChemDiv3_002041 O=C(N1CCN(Cc2ccc3OCOc3c2)CC1)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M18 compound treatment 963092.0 256000.0 0.54 1136700.0 328000.0 0.75 0.9116 0.9877 3118760 ChemDiv3_002042 COC(=O)/C(=C/c1c[nH]c2ccccc12)/NC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M19 compound treatment 1183468.0 476000.0 1.01 1423295.0 615000.0 1.4 1.7027 0.9873 1397577 ChemDiv3_002043 Nc1c(nc2ccccn12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M20 compound treatment 1124297.0 417000.0 0.88 1021112.0 213000.0 0.48 0.9675 0.9597 3021354 ChemDiv3_002044 CCN1C(=O)/C(=C/C=C/c2ccco2)/C(=O)NC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M21 compound treatment 244453.0 -463000.0 -0.98 233899.0 -574000.0 -1.31 -1.617 -0.99 1484277 ChemDiv3_002045 O=C(C1CC1)N2c3ccccc3CCc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M22 compound treatment 935704.0 229000.0 0.48 829597.0 21200.0 0.05 0.3769 0.7737 3118761 ChemDiv3_002046 Cc1cccc2c1nc3s/c(=C/c4c[nH]nc4c5ccccc5)/c(=O)n32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M23 mock treatment 977858.0 271000.0 0.57 924055.0 116000.0 0.26 0.5919 0.9374 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 M24 mock treatment 517003.0 -190000.0 -0.4 726096.0 -82300.0 -0.19 -0.4172 -0.9391 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N01 compound treatment 601705.0 -105000.0 -0.22 697518.0 -111000.0 -0.25 -0.3362 -0.9982 3021358 ChemDiv3_002047 Fc1ccccc1N2C(=O)NC(=O)/C(=C\NCCC3=CCCCC3)/C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N02 compound treatment 794230.0 87200.0 0.18 1108506.0 300000.0 0.68 0.6132 0.8673 1546469 ChemDiv3_002048 OC(=O)c1ccccc1C(=O)OCCN2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N03 compound treatment 795241.0 88200.0 0.19 1192329.0 384000.0 0.87 0.7494 0.8395 3021361 ChemDiv3_002049 Cn1cnnc1SCC(=O)NCc2cccc(c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N04 compound treatment 710147.0 3070.0 0.01 1146621.0 338000.0 0.77 0.5484 0.7131 1201390 ChemDiv3_002050 CC1C(NC(C(C)C1=O)c2ccc(cc2)N(C)C)c3ccc(cc3)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N05 compound treatment 859449.0 152000.0 0.32 1194560.0 386000.0 0.88 0.8493 0.9078 1193866 ChemDiv3_002051 OC(=O)c1c2CCCCc2nc3ccc(Br)cc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N06 compound treatment 697203.0 -9870.0 -0.02 832552.0 24200.0 0.05 0.0241 0.4094 3118762 ChemDiv3_002052 CC(=O)OC1CCC2C3CCc4cc(OC(=O)C)c(Br)cc4C3CCC12C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N07 compound treatment 856485.0 149000.0 0.32 1053266.0 245000.0 0.56 0.6177 0.9643 1701950 ChemDiv3_002053 Fc1ccc(cc1)N2CCN(CC2)C(=O)Cc3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N08 compound treatment 908711.0 202000.0 0.43 1161946.0 354000.0 0.8 0.8707 0.9563 3118763 ChemDiv3_002054 Cn1c(/N=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N09 compound treatment 925289.0 218000.0 0.46 1204400.0 396000.0 0.9 0.9638 0.9521 3118764 ChemDiv3_002055 Cc1ccc(cc1)C2OCC3(CO2)COC(OC3)c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N10 compound treatment 1042487.0 335000.0 0.71 1254716.0 446000.0 1.01 1.2204 0.9849 3021365 ChemDiv3_002056 Cc1ccc(cc1)S(=O)(=O)/C(=C/c2ccc(o2)c3ccc(Cl)cc3)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N11 compound treatment 1056600.0 350000.0 0.74 1241923.0 434000.0 0.99 1.221 0.9901 1540197 ChemDiv3_002057 COc1ccc2oc(C)c(C(=O)CSc3ccccc3)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N12 compound treatment 211558.0 -496000.0 -1.05 211716.0 -597000.0 -1.36 -1.702 -0.992 1543540 ChemDiv3_002058 CCCn1c(nc2ccccc12)C(O)c3ccc(cc3)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N13 compound treatment 851965.0 145000.0 0.31 1243103.0 435000.0 0.99 0.9161 0.8851 3118765 ChemDiv3_002059 CC(=O)/N=C(\N)/Nc1nc2ccccc2o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N14 compound treatment 928035.0 221000.0 0.47 1133484.0 325000.0 0.74 0.8539 0.9758 3021368 ChemDiv3_002060 O=C1OC(OC(=O)C1=Cc2cccs2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N15 compound treatment 1014314.0 307000.0 0.65 1198347.0 390000.0 0.89 1.0875 0.9885 1445360 ChemDiv3_002061 CN1c2ccccc2C(C)(C)C31Cc4cc(NS(=O)(=O)c5ccc(Cl)cc5)ccc4O3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N16 compound treatment 967826.0 261000.0 0.55 1268839.0 460000.0 1.05 1.1312 0.9555 3021615 ChemDiv3_002062 COc1cc2CC(C)(C)N/C(=N\N)/c2cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N17 compound treatment 992779.0 286000.0 0.61 1133758.0 325000.0 0.74 0.9514 0.9951 3118766 ChemDiv3_002063 COc1ccccc1OCCn2cc(/C=C\3/SC(=S)N(CC=C)C3=O)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N18 compound treatment 1057008.0 350000.0 0.74 1221210.0 413000.0 0.94 1.1883 0.9932 1141689 ChemDiv3_002064 Nc1ccc2nc(NC(=O)C3(CC4CC5CC(C4)C3)C5)sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N19 compound treatment 651510.0 -55600.0 -0.12 604394.0 -204000.0 -0.46 -0.4112 -0.8594 3021663 ChemDiv3_002065 COc1ccc(/N=C/2\CCCc3ccccc3N2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N20 compound treatment 1074162.0 367000.0 0.78 1087865.0 280000.0 0.64 0.9996 0.9949 1293367 ChemDiv3_002066 COC(=O)c1c(C)oc2ccc(OC(=O)c3ccc(OC)cc3)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N21 compound treatment 794410.0 87300.0 0.19 733222.0 -75100.0 -0.17 0.0101 0.0402 1917815 ChemDiv3_002067 Clc1ccc(CSc2cn3CCCc3n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N22 compound treatment 986917.0 280000.0 0.59 1091347.0 283000.0 0.64 0.8744 0.9992 3021666 ChemDiv3_002068 CC(C)c1ccc(C=C2C(=O)NC(=O)NC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N23 mock treatment 878501.0 171000.0 0.36 1093216.0 285000.0 0.65 0.7149 0.9627 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 N24 mock treatment 629906.0 -77200.0 -0.16 797853.0 -10500.0 -0.02 -0.1326 -0.8019 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O01 compound treatment 563031.0 -144000.0 -0.31 620075.0 -188000.0 -0.43 -0.5186 -0.9863 3118767 ChemDiv3_002069 COc1cccc2s/c(=N/C(=O)c3ccccc3)/n(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O02 compound treatment 483410.0 -224000.0 -0.47 527639.0 -281000.0 -0.64 -0.7866 -0.9893 1397032 ChemDiv3_002070 Oc1cc(O)nc(SCC(=O)N2c3ccccc3Sc4ccccc24)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O03 compound treatment 940602.0 234000.0 0.5 1232633.0 424000.0 0.96 1.0321 0.952 3118768 ChemDiv3_002071 COc1cc(/C=C/C(=O)O)cc(c1OC)S(=O)(=O)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O04 compound treatment 949655.0 243000.0 0.51 1076339.0 268000.0 0.61 0.7944 0.9964 3021669 ChemDiv3_002072 O=C(/N=c/1\[nH]c(=O)c2ccccc2s1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O05 compound treatment 1015211.0 308000.0 0.65 1232697.0 424000.0 0.96 1.1441 0.982 3118769 ChemDiv3_002073 CN(C)/C(=N/S(=O)(=O)c1cc(C)ccc1C)/c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O06 compound treatment 1027217.0 320000.0 0.68 1130520.0 322000.0 0.73 0.9978 0.9993 3021673 ChemDiv3_002074 COc1ccc(cc1)C(=S)N2CCC(C)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O07 compound treatment 985202.0 278000.0 0.59 1125045.0 317000.0 0.72 0.926 0.9951 3118916 ChemDiv3_002075 Cc1ccc(/C=C/C(=O)O)cc1S(=O)(=O)N2CCC(CC2)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O08 compound treatment 1153752.0 447000.0 0.95 1340696.0 532000.0 1.21 1.5254 0.9926 3118917 ChemDiv3_002076 O=C/1N(C2=C(CCCC2)C(=O)\C1=C\Nc3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O09 compound treatment 805150.0 98100.0 0.21 1213963.0 406000.0 0.92 0.7991 0.8453 1215882 ChemDiv3_002077 NNC(=O)CCn1c(c(c2ccccc2)c3ccccc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O10 compound treatment 1114403.0 407000.0 0.86 1157784.0 349000.0 0.79 1.1723 0.9991 1725909 ChemDiv3_002078 CC(=O)Nc1cc(NC(=O)C)c2nc(N)sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O11 compound treatment 1090822.0 384000.0 0.81 1238503.0 430000.0 0.98 1.2668 0.9958 3020973 ChemDiv3_002079 COc1cc(cc(OC)c1OC)C(=O)NN2CCN(C)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O12 compound treatment 1145230.0 438000.0 0.93 1192907.0 385000.0 0.87 1.275 0.9995 1397238 ChemDiv3_002080 COc1cccc(c1)c2nc([nH]c2c3cccc(OC)c3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O13 compound treatment 1190275.0 483000.0 1.02 1407947.0 600000.0 1.36 1.6883 0.9901 1464925 ChemDiv3_002081 Cc1ccc(cc1)S(=O)(=O)NCC2OCCc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O14 compound treatment 1061661.0 355000.0 0.75 1115129.0 307000.0 0.7 1.0247 0.9993 1524063 ChemDiv3_002082 CC1(C)CC(=O)C2=C(C1)Oc3ccccc3C2CC(=O)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O15 compound treatment 1220303.0 513000.0 1.09 1257837.0 449000.0 1.02 1.4919 0.9995 1607555 ChemDiv3_002083 CC(C)Oc1ccc(Cc2c(O)nc(SCc3ccccc3)nc2O)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O16 compound treatment 198108.0 -509000.0 -1.08 102158.0 -706000.0 -1.61 -1.8983 -0.9813 1471552 ChemDiv3_002084 Oc1ccc(NCN2C(=O)C3C4CC(C=C4)C3C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O17 compound treatment 934763.0 228000.0 0.48 1120189.0 312000.0 0.71 0.8426 0.9824 1326920 ChemDiv3_002085 Brc1ccccc1CN2CCN(CC2)C(=O)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O18 compound treatment 938794.0 232000.0 0.49 1063592.0 255000.0 0.58 0.7577 0.9966 3021020 ChemDiv3_002086 Nc1ccc2oc(=O)c(cc2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O19 compound treatment 1342825.0 636000.0 1.35 1057663.0 249000.0 0.57 1.3538 0.9259 1185960 ChemDiv3_002087 CCCCc1nn2c(=O)cc(O)nc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O20 compound treatment 1129261.0 422000.0 0.9 920351.0 112000.0 0.25 0.8129 0.8736 1185069 ChemDiv3_002088 CSc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O21 compound treatment 159662.0 -547000.0 -1.16 143187.0 -665000.0 -1.51 -1.89 -0.9914 3021024 ChemDiv3_002089 COc1ccc2c(C)nc(NC(=N)/N=C(\C)/c3ccccc3C(=O)O)nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O22 compound treatment 1045906.0 339000.0 0.72 955245.0 147000.0 0.33 0.7441 0.9393 3442330 ChemDiv3_002090 O=C1C2CC=CCC2C(=O)N1CNc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O23 mock treatment 997649.0 291000.0 0.62 854037.0 45700.0 0.1 0.509 0.8148 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 O24 mock treatment 507931.0 -199000.0 -0.42 547380.0 -261000.0 -0.59 -0.7181 -0.9861 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P01 compound treatment 438612.0 -268000.0 -0.57 425591.0 -383000.0 -0.87 -1.0178 -0.9788 3118918 ChemDiv3_002091 CCN(CC)CCN/C=C/1\C(=O)NC(=O)N(C1=O)c2ccccc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P02 compound treatment 420888.0 -286000.0 -0.61 504970.0 -303000.0 -0.69 -0.9168 -0.998 1679160 ChemDiv3_002092 CCOC(=O)C(C1CCCCC1)C(=O)Nc2ccc(cc2)N(CC)CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P03 compound treatment 668817.0 -38300.0 -0.08 842117.0 33800.0 0.08 -0.0031 -0.0276 3118919 ChemDiv3_002093 Fc1ccc(CN2C(=O)c3cccc4cccc2c34)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P04 compound treatment 321651.0 -385000.0 -0.82 395229.0 -413000.0 -0.94 -1.2419 -0.9976 3021032 ChemDiv3_002094 CCN(CC)CCSc1nc2ccccc2c(=S)n1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P05 compound treatment 726866.0 19800.0 0.04 1196840.0 388000.0 0.88 0.6542 0.7399 3118920 ChemDiv3_002095 Brc1cccc(/C=C/2\SC(=S)N(CC(=O)NCCc3ccccc3)C2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P06 compound treatment 699958.0 -7120.0 -0.02 1106081.0 298000.0 0.68 0.468 0.6912 3118921 ChemDiv3_002096 Oc1ccccc1c2nc(no2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P07 compound treatment 602986.0 -104000.0 -0.22 942712.0 134000.0 0.31 0.06 0.1591 1122737 ChemDiv3_002097 C(c1ccccc1)n2c-3c(CCc4nonc43)c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P08 compound treatment 951178.0 244000.0 0.52 852435.0 44100.0 0.1 0.4368 0.8286 3118922 ChemDiv3_002098 CCOc1ccc2n(C)c(S)nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P09 compound treatment 998880.0 292000.0 0.62 1074232.0 266000.0 0.6 0.8648 0.9999 1696348 ChemDiv3_002099 Ic1cn(Cc2ccccc2)c(=O)n(Cc3ccccc3)c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P10 compound treatment 909445.0 202000.0 0.43 968628.0 160000.0 0.36 0.561 0.9967 3021064 ChemDiv3_002100 C=CCN1C(=O)/C(=C/2\SC(=NC2=O)N3CCCCC3)/c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P11 compound treatment 867393.0 160000.0 0.34 1052964.0 245000.0 0.56 0.6336 0.9721 1341945 ChemDiv3_002101 CC(=O)Oc1ccc(cc1)C(=O)N(C(=O)c2ccc(OC(=O)C)cc2)c3cc(C)ccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P12 compound treatment 511412.0 -196000.0 -0.41 695788.0 -113000.0 -0.26 -0.4743 -0.9731 1706099 ChemDiv3_002102 Brc1ccc(CNc2ccc3n(cnc3c2)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P13 compound treatment 1090915.0 384000.0 0.81 901905.0 93500.0 0.21 0.7258 0.8629 3118923 ChemDiv3_002103 Cc1ccc(cc1)C(=O)/N=C(\N)/Nc2nc3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P14 compound treatment 1145838.0 439000.0 0.93 1195563.0 387000.0 0.88 1.2802 0.9996 3118924 ChemDiv3_002104 Brc1cccc(c1)c2ccc(C=C3C(=O)OC(OC3=O)c4ccccc4)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P15 compound treatment 1129867.0 423000.0 0.9 1252277.0 444000.0 1.01 1.3474 0.9982 1477399 ChemDiv3_002105 Oc1ccc(NS(=O)(=O)c2ccccc2)cc1Sc3nc4ccccc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P16 compound treatment 1152324.0 445000.0 0.94 1055245.0 247000.0 0.56 1.0643 0.9692 3118925 ChemDiv3_002106 CCOC(=O)/C(=N\O)/C1=NC2(CCCC2)Cc3cc(OC)c(OC)cc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P17 compound treatment 1153258.0 446000.0 0.95 1010080.0 202000.0 0.46 0.9931 0.9448 3021069 ChemDiv3_002107 Fc1ccccc1CNn2c(nc3ccccc3c2=O)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P18 compound treatment 925497.0 218000.0 0.46 865450.0 57100.0 0.13 0.4192 0.8717 1607792 ChemDiv3_002108 Cc1nc2ccccc2c(=O)n1NCc3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P19 compound treatment 746302.0 39200.0 0.08 859741.0 51400.0 0.12 0.1414 0.9861 3021070 ChemDiv3_002109 COc1ccc(CC/N=C\2/CCc3ccccc3N2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P20 compound treatment 1045453.0 338000.0 0.72 1534503.0 726000.0 1.65 1.6746 0.9303 1449139 ChemDiv3_002110 CCC1CCCCN1Cc2c(O)ccc3cc(c4nc5ccccc5[nH]4)c(=O)oc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P21 compound treatment 1076704.0 370000.0 0.78 947929.0 140000.0 0.32 0.7785 0.9208 3118926 ChemDiv3_002111 FC(F)(F)c1cccc(CNC=C2C(=O)CC(CC2=O)c3ccccc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P22 compound treatment 237708.0 -469000.0 -1.0 160129.0 -648000.0 -1.47 -1.7457 -0.9817 1566538 ChemDiv3_002112 Cc1c(C)c2ccccc2n1CC(O)CNC3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P23 mock treatment 587165.0 -120000.0 -0.25 639354.0 -169000.0 -0.38 -0.4515 -0.9799 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2006 P24 mock treatment 478164.0 -229000.0 -0.49 472165.0 -336000.0 -0.76 -0.8836 -0.976 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A01 compound treatment 439452.0 -320000.0 -0.68 461404.0 -277000.0 -0.63 -0.9254 -0.9993 1286976 ChemDiv3_003169 COc1ccc(cc1)n2c(NN)nc3sc4CCCc4c3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A02 compound treatment 349456.0 -410000.0 -0.87 461970.0 -277000.0 -0.63 -1.0594 -0.9873 1560637 ChemDiv3_003170 COC(=O)c1c(C)oc2ccc(cc12)N(C(=O)C)S(=O)(=O)c3ccc4ccccc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A03 compound treatment 412516.0 -347000.0 -0.74 521142.0 -217000.0 -0.49 -0.8697 -0.9813 3119379 ChemDiv3_003171 CCN(CC)S(=O)(=O)c1ccc(cc1)c2cs/c(=N\c3ccc(C)cc3)/n2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A04 compound treatment 553583.0 -206000.0 -0.44 588963.0 -150000.0 -0.34 -0.5492 -0.9924 1585858 ChemDiv3_003172 CC1(CC2(C)CC3(C)C1)CC(C2)(C3)C(=O)NC(=S)N4CCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A05 compound treatment 494296.0 -265000.0 -0.56 439256.0 -299000.0 -0.68 -0.8788 -0.9955 1866874 ChemDiv3_003173 CN(CC(O)Cn1c2ccccc2c3ccccc13)S(=O)(=O)c4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A06 compound treatment 521199.0 -238000.0 -0.51 598108.0 -140000.0 -0.32 -0.5831 -0.9755 1618410 ChemDiv3_003174 CC1(C)Cc2c(CO1)sc3nc(NN)n(Cc4ccccc4)c(=O)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A07 compound treatment 129219.0 -630000.0 -1.34 125847.0 -613000.0 -1.39 -1.9299 -0.9998 1669656 ChemDiv3_003175 C(NC1CCCc2c1[nH]c3ccc(cc23)c4ccccc4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A08 compound treatment 249610.0 -510000.0 -1.08 205549.0 -533000.0 -1.21 -1.6213 -0.9984 3023072 ChemDiv3_003176 Cc1cc(NC2CCCCC2)nc(NCc3ccccc3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A09 compound treatment 629308.0 -130000.0 -0.28 621980.0 -117000.0 -0.26 -0.3826 -0.9998 1313123 ChemDiv3_003177 Clc1ccccc1C(=O)Nc2ccc(cc2)c3nc4ccccc4o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A10 compound treatment 871274.0 112000.0 0.24 705511.0 -33000.0 -0.08 0.1144 0.4604 1391391 ChemDiv3_003178 O=C(CN1C(=O)c2ccccc2C1=O)N(c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A11 compound treatment 550882.0 -209000.0 -0.44 570866.0 -168000.0 -0.38 -0.5824 -0.9973 1356650 ChemDiv3_003179 Fc1ccccc1Nc2nc(NCc3ccccc3)c4ccccc4n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A12 compound treatment 421237.0 -338000.0 -0.72 490123.0 -248000.0 -0.56 -0.9065 -0.993 3119380 ChemDiv3_003180 COc1ccc(/C=C/2\SC(=S)N(CC3CCCO3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A13 compound treatment 524889.0 -235000.0 -0.5 637246.0 -101000.0 -0.23 -0.5146 -0.9387 1433370 ChemDiv3_003181 Cc1ccc(cc1)C(=O)Nc2cccc(c2)c3nc4ccccc4o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A14 compound treatment 469191.0 -290000.0 -0.62 593984.0 -145000.0 -0.33 -0.6677 -0.9568 1026172 ChemDiv3_003182 NC(=N)Nc1nc2ccccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A15 compound treatment 453748.0 -306000.0 -0.65 698736.0 -39800.0 -0.09 -0.5224 -0.7981 3119381 ChemDiv3_003183 CC(=O)Nc1c(O)[nH]c2ccc(C)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A16 compound treatment 463817.0 -296000.0 -0.63 650413.0 -88100.0 -0.2 -0.585 -0.8888 1236383 ChemDiv3_003184 Fc1ccccc1C(=O)n2c3CCCCc3c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A17 compound treatment 491700.0 -268000.0 -0.57 668619.0 -69900.0 -0.16 -0.5139 -0.8715 3023073 ChemDiv3_003185 CCSc1nc2ccccc2n1C(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A18 compound treatment 560336.0 -199000.0 -0.42 479517.0 -259000.0 -0.59 -0.715 -0.9867 3119528 ChemDiv3_003186 CCC(N1C(=O)c2ccccc2C1=O)C(=O)N3c4ccccc4Sc5ccc(cc35)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A19 compound treatment 590925.0 -169000.0 -0.36 561545.0 -177000.0 -0.4 -0.5373 -0.9983 1545724 ChemDiv3_003187 COc1ccc(cc1)C2N(CCN2C(=O)c3ccc(C)cc3)C(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A20 compound treatment 655082.0 -104000.0 -0.22 514290.0 -224000.0 -0.51 -0.5171 -0.9303 3119529 ChemDiv3_003188 Cc1cc(C)c(C#N)c(SCc2ccccc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A21 compound treatment 548019.0 -212000.0 -0.45 485989.0 -253000.0 -0.57 -0.7231 -0.9925 1360295 ChemDiv3_003189 CCCC(=O)Oc1ccc(cc1)N(C(=O)CCC)S(=O)(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A22 compound treatment 487354.0 -272000.0 -0.58 500440.0 -238000.0 -0.54 -0.7908 -0.9995 1447802 ChemDiv3_003190 Fc1ccc(cc1)C(=O)N2c3ccccc3C=Cc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A23 mock treatment 491215.0 -268000.0 -0.57 456126.0 -282000.0 -0.64 -0.8563 -0.9982 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 A24 mock treatment 432730.0 -327000.0 -0.69 445144.0 -293000.0 -0.67 -0.9616 -0.9998 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B01 compound treatment 592933.0 -167000.0 -0.35 505928.0 -233000.0 -0.53 -0.6237 -0.9808 3119530 ChemDiv3_003191 CC1C=CCC2C1C(=O)N(C2=O)c3cccc(Cl)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B02 compound treatment 813400.0 53800.0 0.11 890402.0 152000.0 0.35 0.3249 0.8933 3119531 ChemDiv3_003192 Nc1nc(SC/C=C/c2ccccc2)nc3sc4CCCCc4c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B03 compound treatment 1010988.0 251000.0 0.53 945514.0 207000.0 0.47 0.7097 0.9981 1464526 ChemDiv3_003193 CCOC(=O)c1c(NC(=O)c2ccco2)sc3C(=O)CCCc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B04 compound treatment 851947.0 92400.0 0.2 779322.0 40800.0 0.09 0.2041 0.9417 3119532 ChemDiv3_003194 CCOC(=O)c1c(C)oc-2c1/C(=C/NCCC3=CCCCC3)/C(=O)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B05 compound treatment 1104652.0 345000.0 0.73 875442.0 137000.0 0.31 0.7374 0.9275 3119533 ChemDiv3_003195 OC(=O)CCN1C(=O)/C(=C/c2ccccn2)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B06 compound treatment 1134643.0 375000.0 0.8 1196847.0 458000.0 1.04 1.2991 0.9911 3119534 ChemDiv3_003196 CCOC(=O)C1=CC(=C2C(=O)NC(=O)NC2=O)c3ccccc3O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B07 compound treatment 1019784.0 260000.0 0.55 1153059.0 415000.0 0.94 1.0565 0.9675 3023099 ChemDiv3_003197 FC(F)(F)c1ccccc1NC(=O)CN2C(=O)/C(=C/c3ccccc3Cl)/SC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B08 compound treatment 948368.0 189000.0 0.4 918940.0 180000.0 0.41 0.5731 0.9999 1219353 ChemDiv3_003198 O=C(CSC1=C(C#N)C(CC(=O)N1)c2ccccc2)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B09 compound treatment 1045922.0 286000.0 0.61 953465.0 215000.0 0.49 0.7748 0.9942 3023100 ChemDiv3_003199 CN(Cc1ccccc1)C(=S)NC(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B10 compound treatment 1049835.0 290000.0 0.62 994467.0 256000.0 0.58 0.8466 0.9996 3119535 ChemDiv3_003200 Cc1[nH]c2ccccc2c1C(Nc3cccc(c3)C(F)(F)F)c4ccccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B11 compound treatment 909643.0 150000.0 0.32 989095.0 251000.0 0.57 0.6278 0.9621 1069911 ChemDiv3_003201 Cc1ccc(cc1)S(=O)(=O)N2CN3CN(CN(C2)C3)S(=O)(=O)c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B12 compound treatment 953925.0 194000.0 0.41 1008885.0 270000.0 0.61 0.726 0.9811 1300854 ChemDiv3_003202 CN(Cc1ccccc1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccc4sc(C)nc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B13 compound treatment 1000662.0 241000.0 0.51 1049227.0 311000.0 0.71 0.8609 0.9874 1562840 ChemDiv3_003203 CC(C)Cc1ccc(cc1)C(C)C(=O)NC(C)Cc2c[nH]c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B14 compound treatment 869878.0 110000.0 0.23 1051527.0 313000.0 0.71 0.6686 0.8925 3119536 ChemDiv3_003204 CCOC(=O)C1=CC(=C2C(=O)N(CC)C(=S)N(CC)C2=O)c3ccccc3O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B15 compound treatment 973322.0 214000.0 0.45 920432.0 182000.0 0.41 0.6129 0.999 1519780 ChemDiv3_003205 NS(=O)(=O)c1ccc(NC(=O)C2CCCNC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B16 compound treatment 998924.0 239000.0 0.51 932269.0 194000.0 0.44 0.6703 0.9975 1286586 ChemDiv3_003206 CCOC(=O)c1c(oc2ccc(OCc3ccc(cc3)C(=O)OC)cc12)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B17 compound treatment 955779.0 196000.0 0.42 1049263.0 311000.0 0.71 0.7937 0.9681 1529438 ChemDiv3_003207 CCc1ccc(cc1)n2nc3ccc(NC(=O)c4ccccc4Br)cc3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B18 compound treatment 991712.0 232000.0 0.49 1061096.0 323000.0 0.73 0.8666 0.9812 3119537 ChemDiv3_003208 CCc1nnc2c3c(c(C)sc3ncn12)c4ccc(F)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B19 compound treatment 1276215.0 517000.0 1.1 940812.0 202000.0 0.46 1.0997 0.9257 3119538 ChemDiv3_003209 CC1=CCC2(C(C1)c3ccc(Br)cc3)C(=O)OC(C)(C)OC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B20 compound treatment 1263010.0 503000.0 1.07 972824.0 234000.0 0.53 1.1313 0.9485 3023101 ChemDiv3_003210 C1CCc2c(C1)c(nc3ccc4ccccc4c23)c5ccco5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B21 compound treatment 820298.0 60700.0 0.13 741261.0 2730.0 0.01 0.0954 0.7403 3119539 ChemDiv3_003211 Clc1ccc(OCCn2c(NC(=S)Nc3ccccc3)nc4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B22 compound treatment 778542.0 19000.0 0.04 646446.0 -92100.0 -0.21 -0.1196 -0.5609 3023102 ChemDiv3_003212 CCOC(=O)N1CCN(CC1)C(=O)/C(=C/c2ccccc2Cl)/c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B23 mock treatment 664407.0 -95200.0 -0.2 711462.0 -27100.0 -0.06 -0.1862 -0.8827 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 B24 mock treatment 469291.0 -290000.0 -0.62 506489.0 -232000.0 -0.53 -0.8082 -0.9971 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C01 compound treatment 469070.0 -290000.0 -0.62 541448.0 -197000.0 -0.45 -0.7523 -0.9878 3119540 ChemDiv3_003213 CCC1(CN(CC2(CC)CN(C1)S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C02 compound treatment 849752.0 90200.0 0.19 763260.0 24700.0 0.06 0.175 0.8778 1175485 ChemDiv3_003214 CCOC(=O)c1c(oc2ccc(NS(=O)(=O)c3ccc(CC)cc3)cc12)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C03 compound treatment 924165.0 165000.0 0.35 996276.0 258000.0 0.59 0.6611 0.9693 3023103 ChemDiv3_003215 CCOc1ccc(/N=c/2\scc(c3ccc(Cl)s3)n2C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C04 compound treatment 748874.0 -10700.0 -0.02 637088.0 -101000.0 -0.23 -0.1791 -0.7728 3023104 ChemDiv3_003216 O=C1c2ccccc2C(=Cc3cccs3)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C05 compound treatment 514949.0 -245000.0 -0.52 472545.0 -266000.0 -0.6 -0.7943 -0.9971 3119541 ChemDiv3_003217 CC1=C(C(NC(=O)N1)c2ccc(C)cc2)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C06 compound treatment 1290428.0 531000.0 1.13 1031829.0 293000.0 0.67 1.2673 0.9688 1374480 ChemDiv3_003218 CCNC(=S)Nc1sc2COC(C)(C)Cc2c1C(=O)OCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C07 compound treatment 1046631.0 287000.0 0.61 960611.0 222000.0 0.5 0.7874 0.9957 1491281 ChemDiv3_003219 CCNC(=O)C1CCCc2c1[nH]c3ccc(Cl)cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C08 compound treatment 992733.0 233000.0 0.49 926839.0 188000.0 0.43 0.6523 0.9974 3023105 ChemDiv3_003220 Cc1cc(OCC=C)nc(n1)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C09 compound treatment 1079761.0 320000.0 0.68 1107875.0 369000.0 0.84 1.0738 0.9944 1399234 ChemDiv3_003221 CCc1ccc2oc(nc2c1)c3ccc(NC(=O)c4ccccc4)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C10 compound treatment 825967.0 66400.0 0.14 801030.0 62500.0 0.14 0.2 1.0 1371725 ChemDiv3_003222 O=P(CN(CC1CCCO1)Cc2cccs2)(c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C11 compound treatment 1105602.0 346000.0 0.73 897856.0 159000.0 0.36 0.7749 0.9471 3023106 ChemDiv3_003223 CCOC(=O)c1cnn(c1N)c2ncnc3sc4CCCCc4c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C12 compound treatment 644249.0 -115000.0 -0.24 562864.0 -176000.0 -0.4 -0.4553 -0.9722 3119542 ChemDiv3_003224 O=C/1N(CC2CCCO2)C(=S)S\C1=C/C3CCC=CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C13 compound treatment 1192962.0 433000.0 0.92 1039702.0 301000.0 0.68 1.1339 0.9895 1425019 ChemDiv3_003225 COc1ccc(cc1)C(=O)Nc2cccc(c2)c3nc4ccccc4o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C14 compound treatment 1021692.0 262000.0 0.56 895257.0 157000.0 0.36 0.6449 0.9769 3119543 ChemDiv3_003226 CC1CC(C)(C)N(C(=O)c2ccccc2F)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C15 compound treatment 958622.0 199000.0 0.42 822561.0 84000.0 0.19 0.4335 0.9358 3023107 ChemDiv3_003227 CCOC(=O)c1cccc2/C(=N\O)/c3ccccc3-c21 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C16 compound treatment 272850.0 -487000.0 -1.03 201905.0 -537000.0 -1.22 -1.5923 -0.9965 3119544 ChemDiv3_003228 CCOC(=O)C1=CS/C(=C\2/C(=S)C(C)(C)N(C(=O)CC(C)C)c3ccc(OCC)cc23)/S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C17 compound treatment 914651.0 155000.0 0.33 1069433.0 331000.0 0.75 0.7645 0.9311 1029312 ChemDiv3_003229 OC(=O)c1ccc(cc1)S(=O)(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C18 compound treatment 1065796.0 306000.0 0.65 924929.0 186000.0 0.42 0.7587 0.9786 3119545 ChemDiv3_003230 Cc1ccc(cc1)C(=O)N2CCc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C19 compound treatment 1284097.0 525000.0 1.11 852023.0 113000.0 0.26 0.9688 0.8486 3119546 ChemDiv3_003231 CC(C)CCSc1nc(N)c2c3C(C)CCCc3sc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C20 compound treatment 994711.0 235000.0 0.5 991733.0 253000.0 0.58 0.7596 0.9974 3023108 ChemDiv3_003232 CSc1nc(cc(c2cccs2)c1C#N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C21 compound treatment 932867.0 173000.0 0.37 847182.0 109000.0 0.25 0.4345 0.9813 3023109 ChemDiv3_003233 Cc1ccc(cc1)S(=O)(=O)N=C2C=CC(=O)C=C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C22 compound treatment 999522.0 240000.0 0.51 788819.0 50300.0 0.11 0.4406 0.8449 1523680 ChemDiv3_003234 CN1C2CCC1C=C(C2)N(C(=O)c3ccc(Cl)cc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C23 mock treatment 816411.0 56900.0 0.12 742370.0 3840.0 0.01 0.0914 0.7563 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 C24 mock treatment 519354.0 -240000.0 -0.51 494597.0 -244000.0 -0.55 -0.7522 -0.9991 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D01 compound treatment 493080.0 -266000.0 -0.56 679327.0 -59200.0 -0.13 -0.4946 -0.8517 1419514 ChemDiv3_003235 Brc1ccc(cc1)C(=O)COC(=O)C(Cc2ccccc2)N3C(=O)c4ccccc4C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D02 compound treatment 786563.0 27000.0 0.06 948804.0 210000.0 0.48 0.3785 0.7862 1537888 ChemDiv3_003236 CCCn1c(N)nc2n(C)c(=O)n(C)c(=O)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D03 compound treatment 1069069.0 310000.0 0.66 1055971.0 317000.0 0.72 0.9743 0.9989 3119547 ChemDiv3_003237 CCOC(=O)N1CCC(=C(C#N)C(=O)Nc2cc(OC)ccc2OC)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D04 compound treatment 826160.0 66600.0 0.14 882009.0 143000.0 0.33 0.3305 0.9298 3119682 ChemDiv3_003238 CCOC(=O)c1c(C)oc-2c1/C(=C/NCCc3c[nH]c4ccccc34)/C(=O)c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D05 compound treatment 1168547.0 409000.0 0.87 1167796.0 429000.0 0.98 1.3032 0.9983 1526203 ChemDiv3_003239 Cc1cccc(Oc2coc3cc(OC(=O)c4ccc(F)cc4)ccc3c2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D06 compound treatment 1074390.0 315000.0 0.67 1024420.0 286000.0 0.65 0.9315 0.9999 1546958 ChemDiv3_003240 CCN1C(=O)c2cccc3c(ccc1c23)S(=O)(=O)NCCc4ccc(OC)c(OC)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D07 compound treatment 654080.0 -105000.0 -0.22 637274.0 -101000.0 -0.23 -0.3209 -0.9999 3023138 ChemDiv3_003241 CCOC(=O)C1=C(NC(=O)c2ccco2)Oc3ccc4ccccc4c3C1c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D08 compound treatment 753310.0 -6250.0 -0.01 766975.0 28400.0 0.06 0.0364 0.5508 1685642 ChemDiv3_003242 Cc1ccccc1NC(=O)CSC2=C(C#N)C(C3=C(CCCC3=O)N2)c4ccccc4C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D09 compound treatment 944566.0 185000.0 0.39 1037046.0 299000.0 0.68 0.7572 0.966 3023139 ChemDiv3_003243 S=C(NCCCN1CCOCC1)N(Cc2ccccc2)Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D10 compound treatment 1056967.0 297000.0 0.63 1072073.0 334000.0 0.76 0.982 0.9958 3119683 ChemDiv3_003244 Cc1[nH]c2ccccc2c1C(Nc3ccccc3C(F)(F)F)c4ccccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D11 compound treatment 968373.0 209000.0 0.44 1078101.0 340000.0 0.77 0.8589 0.9652 1631606 ChemDiv3_003245 CCOc1ccc(cc1)C(=O)n2cnc3cc(C)c(C)cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D12 compound treatment 761262.0 1700.0 0.0 876438.0 138000.0 0.31 0.2243 0.7152 1137693 ChemDiv3_003246 CCN1C(=O)c2cccc3c(NC(=O)c4ccc(cc4)S(=O)(=O)N5CCCCC5C)ccc1c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D13 compound treatment 999942.0 240000.0 0.51 1358707.0 620000.0 1.41 1.3574 0.9054 1575379 ChemDiv3_003247 O=C(CCCN1C(=O)c2ccccc2C1=O)n3ccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D14 compound treatment 985789.0 226000.0 0.48 1191006.0 452000.0 1.03 1.0665 0.9397 1720106 ChemDiv3_003248 Cc1nn(C(=O)C2CCCN2S(=O)(=O)c3ccccc3)c(C)c1Sc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D15 compound treatment 520944.0 -239000.0 -0.51 710042.0 -28500.0 -0.06 -0.4035 -0.7912 3119684 ChemDiv3_003249 CC(Cc1c[nH]c2ccccc12)N(Cc3ccccc3)Cc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D16 compound treatment 1040705.0 281000.0 0.6 1127966.0 389000.0 0.89 1.0475 0.9815 3023140 ChemDiv3_003250 Brc1ccc(cc1)N2Cc3ccccc3C2=N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D17 compound treatment 1085904.0 326000.0 0.69 1242191.0 504000.0 1.15 1.2989 0.9709 3119685 ChemDiv3_003251 CC1(C)CC(=O)C(=CNn2cnc3ccccc3c2=O)C(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D18 compound treatment 903906.0 144000.0 0.31 955314.0 217000.0 0.49 0.5649 0.9737 3023141 ChemDiv3_003252 Cc1ccc(SCc2cn3cccnc3n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D19 compound treatment 1143120.0 384000.0 0.81 1047227.0 309000.0 0.7 1.0712 0.9973 3023142 ChemDiv3_003253 CC(NC=C1C(=O)OC(C)(C)OC1=O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D20 compound treatment 870331.0 111000.0 0.23 849462.0 111000.0 0.25 0.3444 0.9994 1469730 ChemDiv3_003254 O=C1CC(c2ccccc2)c3c(N1)ccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D21 compound treatment 809765.0 50200.0 0.11 939909.0 201000.0 0.46 0.399 0.8489 3119686 ChemDiv3_003255 Clc1ccc(Cn2c(NC(=S)Nc3ccccc3)nc4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D22 compound treatment 733456.0 -26100.0 -0.06 882979.0 144000.0 0.33 0.1931 0.5798 3023143 ChemDiv3_003256 COc1ccc(NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)c3ccc(OC)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D23 mock treatment 812480.0 52900.0 0.11 773942.0 35400.0 0.08 0.1363 0.9867 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 D24 mock treatment 479875.0 -280000.0 -0.59 537286.0 -201000.0 -0.46 -0.7428 -0.9918 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E01 compound treatment 657612.0 -102000.0 -0.22 658038.0 -80500.0 -0.18 -0.2822 -0.9966 1562483 ChemDiv3_003257 CCSc1nc2sc3CCCc3c2c(=O)n1CCc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E02 compound treatment 811585.0 52000.0 0.11 744420.0 5890.0 0.01 0.0875 0.7871 3119687 ChemDiv3_003258 OC(=O)c1cccc(c1)S(=O)(=O)/N=C\2/C=C(NS(=O)(=O)c3ccccc3)C(=O)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E03 compound treatment 1069197.0 310000.0 0.66 986657.0 248000.0 0.56 0.8631 0.9972 3023144 ChemDiv3_003259 COC(=O)CSc1nc(C)c(Br)c(O)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E04 compound treatment 1054739.0 295000.0 0.63 1148592.0 410000.0 0.93 1.1017 0.9812 1316178 ChemDiv3_003260 CC1(C)CC(=O)C2=C(C1)C(Nc3ccc4ccccc4c23)c5cccnc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E05 compound treatment 982129.0 223000.0 0.47 1078669.0 340000.0 0.77 0.8805 0.9719 1294879 ChemDiv3_003261 COc1ccc(cc1OC)C2NC(=O)NC(=C2C(=O)c3ccccc3)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E06 compound treatment 1117537.0 358000.0 0.76 1165372.0 427000.0 0.97 1.2228 0.9926 3119688 ChemDiv3_003262 C(CC1OCCCO1)Sc2nnc(o2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E07 compound treatment 896485.0 137000.0 0.29 1177839.0 439000.0 1.0 0.9115 0.8764 1321422 ChemDiv3_003263 Cc1ccc2n(C)c3C(CCCc3c2c1)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E08 compound treatment 1104051.0 344000.0 0.73 1167280.0 429000.0 0.97 1.2057 0.9899 1409750 ChemDiv3_003264 O=C1CC(c2csc(n2)c3ccccc3)C4(CCCCC4)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E09 compound treatment 880264.0 121000.0 0.26 801997.0 63500.0 0.14 0.283 0.9632 1852910 ChemDiv3_003265 CN(C)N1C(=C(C#N)C(C2=C1CCCC2=O)c3ccccc3)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E10 compound treatment 1087025.0 327000.0 0.69 1155560.0 417000.0 0.95 1.1613 0.9883 3119689 ChemDiv3_003266 O=c1c(/C=N/CCc2ccccc2)c(NCCc3ccccc3)nc4ccccn14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E11 compound treatment 1025430.0 266000.0 0.56 1232481.0 494000.0 1.12 1.1926 0.9492 3023145 ChemDiv3_003267 CCc1cc2c(SCC(=O)c3ccc(Br)cc3)ncnc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E12 compound treatment 1375371.0 616000.0 1.31 1164705.0 426000.0 0.97 1.6083 0.9892 1550911 ChemDiv3_003268 Cc1ccc(NC(NC(=O)c2cccs2)C(=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E13 compound treatment 1006144.0 247000.0 0.52 1161549.0 423000.0 0.96 1.0497 0.9589 1203438 ChemDiv3_003269 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc2ccc3OCCOc3c2)C4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E14 compound treatment 930395.0 171000.0 0.36 1150915.0 412000.0 0.94 0.919 0.9144 3119690 ChemDiv3_003270 CC1(C)CC(C)(c2ccccc2)c3ccccc3N1C(=O)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E15 compound treatment 1141550.0 382000.0 0.81 1272503.0 534000.0 1.21 1.431 0.9806 3119691 ChemDiv3_003271 CCOc1ccc(cc1C)C(=O)C2=C(O)C(=O)N(CCN(CC)CC)C2c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E16 compound treatment 1132322.0 373000.0 0.79 1164047.0 426000.0 0.97 1.2429 0.995 3023146 ChemDiv3_003272 N/C(=N\C(=O)Nc1ccc(Cl)c(Cl)c1)/Nc2nc3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E17 compound treatment 923941.0 164000.0 0.35 932766.0 194000.0 0.44 0.5587 0.9931 3119692 ChemDiv3_003273 COc1ccc(cc1)C2(CNC(=O)C(c3ccccc3)c4ccccc4)CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E18 compound treatment 942909.0 183000.0 0.39 1204596.0 466000.0 1.06 1.0241 0.9074 3023147 ChemDiv3_003274 Cc1c(C)c2ccccc2n1C(=O)CSc3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E19 compound treatment 273728.0 -486000.0 -1.03 209344.0 -529000.0 -1.2 -1.579 -0.997 3119693 ChemDiv3_003275 Brc1ccc(CN2C(=O)N/C(=C/c3c[nH]c4ccc(Br)cc34)/C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E20 compound treatment 926148.0 167000.0 0.35 1092531.0 354000.0 0.8 0.8188 0.9316 3023148 ChemDiv3_003276 NC(=N)NS(=O)(=O)c1ccc(/N=C/c2cccs2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E21 compound treatment 982265.0 223000.0 0.47 984078.0 246000.0 0.56 0.7286 0.9965 1153257 ChemDiv3_003277 CCCc1oc2c(cc(NS(=O)(=O)c3ccc(CC)cc3)c4ccccc24)c1C(=O)OCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E22 compound treatment 833683.0 74100.0 0.16 931571.0 193000.0 0.44 0.4214 0.9041 1596083 ChemDiv3_003278 OCCNc1ccc2ccccc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E23 mock treatment 762642.0 3080.0 0.01 731207.0 -7330.0 -0.02 -0.0072 -0.4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 E24 mock treatment 436095.0 -323000.0 -0.69 651588.0 -86900.0 -0.2 -0.6247 -0.8753 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F01 compound treatment 612532.0 -147000.0 -0.31 537921.0 -201000.0 -0.46 -0.5429 -0.9828 1378106 ChemDiv3_003279 Cc1cccc(Oc2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4(C)C3=O)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F02 compound treatment 814842.0 55300.0 0.12 879358.0 141000.0 0.32 0.3093 0.9071 1397787 ChemDiv3_003280 COc1ccc(cc1)c2nc(c(SC)[nH]2)S(=O)(=O)c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F03 compound treatment 857829.0 98300.0 0.21 967091.0 229000.0 0.52 0.5147 0.9195 3119694 ChemDiv3_003281 OC(=O)c1cccc(c1)c2ccc(/C=c\3/sc4nc5ccccc5n4c3=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F04 compound treatment 836555.0 77000.0 0.16 841656.0 103000.0 0.23 0.2812 0.9843 3023149 ChemDiv3_003282 CCOC(=O)c1c(C)oc-2c1/C(=C/NC(C)c3ccccc3)/C(=O)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F05 compound treatment 1284972.0 525000.0 1.11 1061988.0 323000.0 0.74 1.3076 0.9797 1703292 ChemDiv3_003283 Cc1cccc(Oc2coc3cc(OC(=O)c4cccnc4)ccc3c2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F06 compound treatment 1070799.0 311000.0 0.66 1353554.0 615000.0 1.4 1.4553 0.9412 1582822 ChemDiv3_003284 Fc1ccccc1c2nc(C#N)c(NCC3CCCO3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F07 compound treatment 766471.0 6910.0 0.01 974305.0 236000.0 0.54 0.3894 0.7262 1065799 ChemDiv3_003285 S=C(Nc1ccccc1)N(Cc2ccccc2)Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F08 compound treatment 670759.0 -88800.0 -0.19 782974.0 44400.0 0.1 -0.0617 -0.2887 3023184 ChemDiv3_003286 CN(C)S(=O)(=O)c1ccc(cc1)C(=O)/N=c/2\sc3cc(ccc3n2C)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F09 compound treatment 957470.0 198000.0 0.42 1137207.0 399000.0 0.91 0.9376 0.9387 3119695 ChemDiv3_003287 CC1=CCC2C(C1)C(=O)N(C2=O)c3cccc(c3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F10 compound treatment 924669.0 165000.0 0.35 1157638.0 419000.0 0.95 0.9213 0.9076 3023185 ChemDiv3_003288 CCc1ccc(NC(=O)CC(NCc2ccccc2)C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F11 compound treatment 1003572.0 244000.0 0.52 1331096.0 593000.0 1.35 1.3184 0.9136 3119854 ChemDiv3_003289 C(c1ccccc1)n2c-3c(CCOc4ccccc34)c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F12 compound treatment 1043364.0 284000.0 0.6 1243624.0 505000.0 1.15 1.2374 0.9545 1658105 ChemDiv3_003290 CC1CCCN(C1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccccc3c4nc5ccccc5[nH]4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F13 compound treatment 143714.0 -616000.0 -1.31 135368.0 -603000.0 -1.37 -1.8928 -0.9997 1261842 ChemDiv3_003291 COc1ccc(cc1)C(=O)O[C@H](C2CC3CCN2CC3C=C)c4ccnc5ccccc45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F14 compound treatment 1293854.0 534000.0 1.13 1371409.0 633000.0 1.44 1.8184 0.993 1569329 ChemDiv3_003292 COc1ccc(cc1)S(=O)(=O)N2CCCC2C(=O)n3nc(C)cc3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F15 compound treatment 1218320.0 459000.0 0.97 1099674.0 361000.0 0.82 1.2683 0.9965 3119855 ChemDiv3_003293 Brc1ccc(NC(=O)C2CC(=O)N(/C(=N/c3ccccc3)/S2)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F16 compound treatment 946036.0 186000.0 0.4 1125546.0 387000.0 0.88 0.9017 0.9348 1411088 ChemDiv3_003294 CCN1C(=O)C(C2CC1(C)Oc3ccccc23)C(=O)N(Cc4ccccc4)Cc5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F17 compound treatment 876668.0 117000.0 0.25 1147641.0 409000.0 0.93 0.8332 0.8655 3023186 ChemDiv3_003295 CNC=C1C(=O)c2ccccc2C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F18 compound treatment 717416.0 -42100.0 -0.09 899237.0 161000.0 0.37 0.1952 0.5189 1692589 ChemDiv3_003296 C(Sc1nc2ccccc2s1)c3cn4cccnc4n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F19 compound treatment 883334.0 124000.0 0.26 961167.0 223000.0 0.51 0.5435 0.9532 3023187 ChemDiv3_003297 COc1ccc(cc1)c2noc(n2)c3cccc(F)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F20 compound treatment 871297.0 112000.0 0.24 922701.0 184000.0 0.42 0.4636 0.9636 1402907 ChemDiv3_003298 ON1C(Nc2ccccc2C1=O)c3cccc(O)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F21 compound treatment 777397.0 17800.0 0.04 902928.0 164000.0 0.37 0.291 0.7747 1260345 ChemDiv3_003299 Cn1c(=O)n(CCOc2ccccc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F22 compound treatment 1045043.0 285000.0 0.61 839561.0 101000.0 0.23 0.5904 0.912 3119856 ChemDiv3_003300 CCOc1ccc(cc1)S(=O)(=O)N(CC(=O)NC2CC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F23 mock treatment 988249.0 229000.0 0.48 832164.0 93600.0 0.21 0.4933 0.9317 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 F24 mock treatment 523408.0 -236000.0 -0.5 573999.0 -165000.0 -0.37 -0.6185 -0.9897 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G01 compound treatment 679225.0 -80300.0 -0.17 786652.0 48100.0 0.11 -0.0431 -0.2128 3119857 ChemDiv3_003301 O=S(=O)(N1CCCC1)c2ccc(cc2)c3cs/c(=N\c4ccccc4)/n3CCc5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G02 compound treatment 1138889.0 379000.0 0.8 1243660.0 505000.0 1.15 1.3807 0.9848 3023188 ChemDiv3_003302 CC1(C)Cc2c(ccc3ccccc23)C(=N1)NCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G03 compound treatment 1096671.0 337000.0 0.71 1277184.0 539000.0 1.22 1.3713 0.9671 3119858 ChemDiv3_003303 CN(C)c1nc(SCCOC(=O)COc2ccc(Cl)cc2Cl)nc(n1)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G04 compound treatment 1103568.0 344000.0 0.73 1067881.0 329000.0 0.75 1.0452 0.9999 1481926 ChemDiv3_003304 O=CNC1c2ccccc2Oc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G05 compound treatment 1192403.0 433000.0 0.92 1095634.0 357000.0 0.81 1.2229 0.9981 1448737 ChemDiv3_003305 OC(=O)CCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G06 compound treatment 955220.0 196000.0 0.41 774724.0 36200.0 0.08 0.3515 0.8312 1566191 ChemDiv3_003306 CCC1C(NC(CC1(O)c2ccc(F)cc2)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G07 compound treatment 1186076.0 427000.0 0.9 1061614.0 323000.0 0.73 1.1588 0.9947 1652661 ChemDiv3_003307 CCN1CCn2c3C1CCCc3c4cc(Cl)ccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G08 compound treatment 1120148.0 361000.0 0.76 1233786.0 495000.0 1.13 1.3367 0.9822 1433683 ChemDiv3_003308 CC1(C)CC(=O)c2c(coc2C1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G09 compound treatment 1237105.0 478000.0 1.01 1258293.0 520000.0 1.18 1.5514 0.997 1852959 ChemDiv3_003309 CCc1ccc(cc1)C2C(=C(N)N(N3CCOCC3)C4=C2C(=O)CC(C)(C)C4)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G10 compound treatment 1426084.0 667000.0 1.41 1588352.0 850000.0 1.93 2.3653 0.9882 3119859 ChemDiv3_003310 CC(C)CN1C(=O)/C(=C/C=C/c2ccccc2)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G11 compound treatment 1077873.0 318000.0 0.67 1706664.0 968000.0 2.2 2.0336 0.8833 3023189 ChemDiv3_003311 Nc1nnnn1/N=C/c2ccc(o2)c3ccc4C(=O)OCc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G12 compound treatment 1315216.0 556000.0 1.18 1791841.0 1050000.0 2.39 2.5263 0.9466 1159102 ChemDiv3_003312 CCOc1ccc(NC(NC(=O)c2cccs2)C(=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G13 compound treatment 1231963.0 472000.0 1.0 1645299.0 907000.0 2.06 2.1659 0.945 3023190 ChemDiv3_003313 CN(CC(=O)Nc1ccc(cc1)S(=O)(=O)N)S(=O)(=O)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G14 compound treatment 1131073.0 372000.0 0.79 1424184.0 686000.0 1.56 1.6592 0.95 3119860 ChemDiv3_003314 Cc1nc(N/C(=N/C(=O)c2ccccc2)/N)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G15 compound treatment 171490.0 -588000.0 -1.25 129448.0 -609000.0 -1.38 -1.8607 -0.9986 1346700 ChemDiv3_003315 Cc1ccc(cc1)C(O)(C(=O)NN2CCOCC2)c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G16 compound treatment 967697.0 208000.0 0.44 935849.0 197000.0 0.45 0.6292 1.0 3023191 ChemDiv3_003316 Cc1cc(C)n(n1)C(=O)Nc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G17 compound treatment 1070905.0 311000.0 0.66 1473040.0 735000.0 1.67 1.6475 0.9175 1424365 ChemDiv3_003317 CC(C)c1ccc(cc1)S(=O)(=O)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G18 compound treatment 1076307.0 317000.0 0.67 1273829.0 535000.0 1.22 1.3354 0.9607 1360094 ChemDiv3_003318 COC(=O)c1ccccc1NC(=O)NC2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G19 compound treatment 1258860.0 499000.0 1.06 1038036.0 300000.0 0.68 1.23 0.9772 3119861 ChemDiv3_003319 COC(=O)c1ccc(/C=C\2/NC(=O)N(Cc3ccc(Br)cc3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G20 compound treatment 1009419.0 250000.0 0.53 975182.0 237000.0 0.54 0.755 1.0 3023192 ChemDiv3_003320 Fc1ccc(NC(=S)N2CCc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G21 compound treatment 846134.0 86600.0 0.18 831350.0 92800.0 0.21 0.279 0.9976 1104701 ChemDiv3_003321 Cc1ccc(cc1)S(=O)(=O)N=C2C=CC(=NS(=O)(=O)c3ccc(C)cc3)C=C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G22 compound treatment 1106546.0 347000.0 0.74 1016760.0 278000.0 0.63 0.9674 0.9972 1056920 ChemDiv3_003322 Cc1ccc(Oc2nc(Cl)nc(Oc3ccc(C)cc3)n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G23 mock treatment 1050349.0 291000.0 0.62 911028.0 172000.0 0.39 0.7132 0.9762 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 G24 mock treatment 639571.0 -120000.0 -0.25 506788.0 -232000.0 -0.53 -0.5524 -0.9442 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H01 compound treatment 732219.0 -27300.0 -0.06 626548.0 -112000.0 -0.25 -0.221 -0.8464 1634360 ChemDiv3_003323 COC(=O)c1cc(nc2ccccc12)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H02 compound treatment 919332.0 160000.0 0.34 1260994.0 522000.0 1.19 1.0794 0.8739 3119862 ChemDiv3_003324 CN1C(=O)NC(C(C(=O)c2cccs2)C1(O)C(F)(F)F)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H03 compound treatment 985703.0 226000.0 0.48 1272330.0 534000.0 1.21 1.1972 0.9174 3119863 ChemDiv3_003325 Cc1ccc(cc1)C(=O)N2N=C3N(C2N4CCCCC4)S(=O)(=O)c5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H04 compound treatment 619617.0 -140000.0 -0.3 643065.0 -95500.0 -0.22 -0.3633 -0.9882 1358055 ChemDiv3_003326 CCOC(=O)c1c(C)oc2c1c3CN(COc3c4ccccc24)C5CCCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H05 compound treatment 1034458.0 275000.0 0.58 1088639.0 350000.0 0.8 0.9749 0.9883 1274629 ChemDiv3_003327 COc1ccc(Nc2ncnc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H06 compound treatment 1089900.0 330000.0 0.7 941843.0 203000.0 0.46 0.822 0.9797 1496041 ChemDiv3_003328 CCSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccc(cc3)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H07 compound treatment 1080198.0 321000.0 0.68 1075569.0 337000.0 0.77 1.0225 0.9982 3023235 ChemDiv3_003329 S=C(NC1CCCCC1)N(Cc2ccccc2)Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H08 compound treatment 1399083.0 640000.0 1.36 1402694.0 664000.0 1.51 2.0264 0.9986 3119864 ChemDiv3_003330 Cn1/c(=N\C(=O)c2cc(nc3ccccc23)c4ccccc4)/sc5cc(ccc15)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H09 compound treatment 1243045.0 483000.0 1.02 1752648.0 1010000.0 2.31 2.3551 0.9334 1302654 ChemDiv3_003331 CC(NC(=O)CSc1nc(N)cc(=O)[nH]1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H10 compound treatment 1466101.0 707000.0 1.5 1799692.0 1060000.0 2.41 2.7651 0.9737 3119865 ChemDiv3_003332 Cc1ccc(NC(=O)CC(NCCc2ccccc2)C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H11 compound treatment 1573279.0 814000.0 1.73 1660043.0 922000.0 2.1 2.7013 0.9953 1349929 ChemDiv3_003333 OCC(=O)c1c[nH]c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H12 compound treatment 1485961.0 726000.0 1.54 1111470.0 373000.0 0.85 1.6885 0.9605 1430458 ChemDiv3_003334 CCCCN(CC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2ccccc2c3nc4ccccc4[nH]3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H13 compound treatment 1184303.0 425000.0 0.9 1396895.0 658000.0 1.5 1.6951 0.9704 1534077 ChemDiv3_003335 O=C1CCC(=O)N1CCc2c[nH]c3ccc(OCc4ccccc4)cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H14 compound treatment 1603489.0 844000.0 1.79 1704996.0 966000.0 2.2 2.8188 0.9948 1226556 ChemDiv3_003336 OC(=O)CSc1nnc(c2ccc3OCOc3c2)n1CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H15 compound treatment 1225279.0 466000.0 0.99 1579256.0 841000.0 1.91 2.0497 0.9528 3119866 ChemDiv3_003337 COc1ccccc1NC(=O)C2CC(=O)N(C)/C(=N/c3ccccc3)/S2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H16 compound treatment 1282910.0 523000.0 1.11 1789076.0 1050000.0 2.39 2.4734 0.9392 1518221 ChemDiv3_003338 O=S1(=O)CC2C(C1)N(C(=S)N2c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H17 compound treatment 1048123.0 289000.0 0.61 1134066.0 396000.0 0.9 1.0684 0.9824 3119867 ChemDiv3_003339 Oc1ccccc1NC=C2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H18 compound treatment 1399761.0 640000.0 1.36 1618355.0 880000.0 2.0 2.3741 0.9821 3023236 ChemDiv3_003340 CCOC(=S)SCc1cn2cccnc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H19 compound treatment 1200455.0 441000.0 0.93 1342140.0 604000.0 1.37 1.6313 0.9825 3119868 ChemDiv3_003341 NC(=O)C1CCN(CC1)C(=O)c2cccc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H20 compound treatment 1263914.0 504000.0 1.07 960775.0 222000.0 0.51 1.1133 0.9414 3120012 ChemDiv3_003342 O=C1c2ccccc2-c3c1c4ccccc4nc3c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H21 compound treatment 1023263.0 264000.0 0.56 820939.0 82400.0 0.19 0.5278 0.8951 3120013 ChemDiv3_003343 Cc1cc(/C=C\2/NC(=O)N(Cc3ccc(Br)cc3)C2=O)c(C)n1c4ccc5OCOc5c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H22 compound treatment 1164475.0 405000.0 0.86 884732.0 146000.0 0.33 0.842 0.9147 3023237 ChemDiv3_003344 Clc1ccccc1/C=C(/C(=O)NCc2ccccn2)\c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H23 mock treatment 1074095.0 315000.0 0.67 903242.0 165000.0 0.37 0.7363 0.9628 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 H24 mock treatment 548705.0 -211000.0 -0.45 619742.0 -119000.0 -0.27 -0.5071 -0.9709 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I01 compound treatment 577246.0 -182000.0 -0.39 708564.0 -30000.0 -0.07 -0.3215 -0.8191 3120014 ChemDiv3_003345 COc1cc(/N=c/2\scc(c3ccc(cc3)S(=O)(=O)N4CCCC4)n2C)c(OC)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I02 compound treatment 1194991.0 435000.0 0.92 1349494.0 611000.0 1.39 1.6349 0.9803 3023238 ChemDiv3_003346 COc1cc2CC(C)(C)N=C(NCCC(=O)O)c2cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I03 compound treatment 973301.0 214000.0 0.45 1362296.0 624000.0 1.42 1.3232 0.8888 3023239 ChemDiv3_003347 COc1cc(C)nc(OCCNS(=O)(=O)c2cc(C)ccc2C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I04 compound treatment 1028476.0 269000.0 0.57 1168979.0 430000.0 0.98 1.0951 0.9669 1482999 ChemDiv3_003348 Cc1ccc(OC(=O)C2c3ccccc3Oc4ccccc24)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I05 compound treatment 1331800.0 572000.0 1.21 1284088.0 546000.0 1.24 1.7349 0.9999 3120015 ChemDiv3_003349 CCC(=O)c1ccc(OC(=O)c2cn(nc2c3ccccc3)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I06 compound treatment 1220516.0 461000.0 0.98 1136545.0 398000.0 0.9 1.3309 0.9993 1537398 ChemDiv3_003350 CCC1C(NC(C(CC)C1=NO)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I07 compound treatment 1641562.0 882000.0 1.87 1871215.0 1130000.0 2.58 3.1431 0.9876 3120016 ChemDiv3_003351 Cn1c2-c3cnn(c3CC(C)(C)c2c4ccccc14)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I08 compound treatment 1064150.0 305000.0 0.65 1538362.0 800000.0 1.82 1.7424 0.903 1580288 ChemDiv3_003352 Cc1cc(C)cc(OCCn2c(nc3ccccc3c2=O)c4ccc(Cl)cc4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I09 compound treatment 1076054.0 316000.0 0.67 1111718.0 373000.0 0.85 1.0744 0.9932 1853000 ChemDiv3_003353 NC1=C(C#N)C(C2=C(CC(CC2=O)c3ccccc3)N1N4CCOCC4)c5ccccc5Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I10 compound treatment 1014875.0 255000.0 0.54 1766671.0 1030000.0 2.34 2.0356 0.8484 3120017 ChemDiv3_003354 COc1ccc(CCN2C(=O)/C(=C/C3CCC=CC3)/SC2=S)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I11 compound treatment 971618.0 212000.0 0.45 1316387.0 578000.0 1.31 1.2469 0.898 3120018 ChemDiv3_003355 COc1cc(/C=C/2\C(=O)N(N=C2C(F)(F)F)c3ccc(cc3)S(=O)(=O)N)ccc1OCC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I12 compound treatment 1260853.0 501000.0 1.06 1689660.0 951000.0 2.16 2.2805 0.9465 1472706 ChemDiv3_003356 CC(=O)Nc1ccc(NC(NC(=O)c2cccs2)C(=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I13 compound treatment 1313298.0 554000.0 1.17 1812727.0 1070000.0 2.44 2.557 0.9436 1582486 ChemDiv3_003357 COc1ccc2[nH]c3nc(=S)[nH]nc3c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I14 compound treatment 310492.0 -449000.0 -0.95 311423.0 -427000.0 -0.97 -1.3598 -1.0 3120019 ChemDiv3_003358 CCC(=O)/N=C(\N)/Nc1nc(C)c2ccccc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I15 compound treatment 1010262.0 251000.0 0.53 1430668.0 692000.0 1.57 1.4885 0.8962 3023240 ChemDiv3_003359 CC(C)(C)C(=O)/C=C/1\Nc2ccccc2OC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I16 compound treatment 1170760.0 411000.0 0.87 1576061.0 838000.0 1.9 1.9628 0.9373 3120020 ChemDiv3_003360 Cc1ccc2NC(C)(C)c3ss/c(=N/c4ccc(cc4)S(=O)(=O)N)/c3-c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I17 compound treatment 1310249.0 551000.0 1.17 1475992.0 737000.0 1.68 2.0111 0.9843 1374353 ChemDiv3_003361 CN(C)C1OC2=C(C=C1C)C(=O)c3cccc4cccc2c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I18 compound treatment 1223398.0 464000.0 0.98 1316602.0 578000.0 1.31 1.6246 0.9898 1323310 ChemDiv3_003362 C1Cc2ccccc2CN1c3nc(Nc4ccccc4)nc(Nc5ccccc5)n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I19 compound treatment 1192458.0 433000.0 0.92 1151781.0 413000.0 0.94 1.3133 0.9999 3120021 ChemDiv3_003363 CC(C)(C)c1ccc(/C=C\2/NC(=O)N(Cc3ccc(Br)cc3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I20 compound treatment 939144.0 180000.0 0.38 920632.0 182000.0 0.41 0.562 0.9991 3023241 ChemDiv3_003364 FC(F)(F)c1cccc(CC(=O)Nc2ccccc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I21 compound treatment 1091969.0 332000.0 0.7 1063490.0 325000.0 0.74 1.0207 0.9997 3120022 ChemDiv3_003365 Fc1ccc(cc1)S(=O)(=O)/N=C/2\C=C(NS(=O)(=O)c3ccccc3)C(=O)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I22 compound treatment 1075318.0 316000.0 0.67 1191786.0 453000.0 1.03 1.202 0.9782 3023242 ChemDiv3_003366 C=CCN1C(=O)/C(=C\c2ccc(OCc3ccccc3C#N)cc2)/C(=O)NC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I23 mock treatment 1006059.0 247000.0 0.52 1231091.0 493000.0 1.12 1.1614 0.9398 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 I24 mock treatment 754199.0 -5360.0 -0.01 717980.0 -20600.0 -0.05 -0.0411 -0.8542 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J01 compound treatment 572503.0 -187000.0 -0.4 787446.0 48900.0 0.11 -0.2018 -0.4899 3120023 ChemDiv3_003367 CCCCC(=O)/C=C/1\Nc2ccccc2NC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J02 compound treatment 486548.0 -273000.0 -0.58 521959.0 -217000.0 -0.49 -0.7574 -0.9968 3120024 ChemDiv3_003368 CCOC(=O)N1CCN(CC1)C(=O)CCN2C(=O)/C(=C/C=C/c3ccccc3)/SC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J03 compound treatment 982876.0 223000.0 0.47 998565.0 260000.0 0.59 0.7528 0.9939 1324615 ChemDiv3_003369 Clc1ccc(cc1)C2SCC(=O)N2Nc3nc(Nc4ccccc4)nc(n3)N5CCCCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J04 compound treatment 150066.0 -609000.0 -1.29 150985.0 -588000.0 -1.34 -1.8582 -0.9999 1715130 ChemDiv3_003370 Clc1cc2CN(CCC3=CCCCC3)COc2c4ncccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J05 compound treatment 1184331.0 425000.0 0.9 1036332.0 298000.0 0.68 1.1155 0.9901 1591815 ChemDiv3_003371 COC(=O)c1ccc(Nc2cc(C)nc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J06 compound treatment 883516.0 124000.0 0.26 829448.0 90900.0 0.21 0.332 0.9929 1445792 ChemDiv3_003372 Fc1ccc(NC(=O)CSC2=C(C#N)C3(CCCCC3)C(C#N)C(=O)N2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J07 compound treatment 1171864.0 412000.0 0.87 1031783.0 293000.0 0.67 1.0895 0.9911 3022562 ChemDiv3_003373 S=C(NC1CCCCC1)N(CC2CCC=CC2)Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J08 compound treatment 1240167.0 481000.0 1.02 1349347.0 611000.0 1.39 1.7024 0.9884 3120025 ChemDiv3_003374 COc1cccc(OC)c1C(=O)/N=c/2\sc3cc(ccc3n2C)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J09 compound treatment 1220928.0 461000.0 0.98 1362288.0 624000.0 1.42 1.6944 0.9836 3022578 ChemDiv3_003375 COc1ccc(cc1)C2=[N+]([O-])C(C)(C)C(=N2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J10 compound treatment 1319722.0 560000.0 1.19 1577713.0 839000.0 1.91 2.1888 0.974 3120026 ChemDiv3_003376 CN(C)C(CC(=O)Nc1ccccc1C)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J11 compound treatment 1281915.0 522000.0 1.11 1875330.0 1140000.0 2.58 2.6106 0.9284 3120027 ChemDiv3_003377 COC(=O)C1O[N+](=C(C1c2c[nH]c3ccccc23)C(=O)OC)[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J12 compound treatment 152856.0 -607000.0 -1.29 128972.0 -610000.0 -1.39 -1.8894 -0.9993 1251370 ChemDiv3_003378 CN(Cc1ccccc1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3ccc(cc3)c4nc5ccccc5[nH]4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J13 compound treatment 1347488.0 588000.0 1.25 1605110.0 867000.0 1.97 2.2745 0.9756 3120028 ChemDiv3_003379 CN1CCc2cc(ccc12)/C(=C/c3ccccc3)/C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J14 compound treatment 1269571.0 510000.0 1.08 1426271.0 688000.0 1.56 1.8702 0.9838 3022585 ChemDiv3_003380 OC(=O)CSc1nnc(c2sc3ccccc3c2Cl)n1CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J15 compound treatment 204654.0 -555000.0 -1.18 176011.0 -563000.0 -1.28 -1.7362 -0.9991 3120029 ChemDiv3_003381 Clc1ccc(NC(=S)N2CCSC2c3ccc(Br)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J16 compound treatment 1141132.0 382000.0 0.81 1521770.0 783000.0 1.78 1.8312 0.9362 1628252 ChemDiv3_003382 Cn1c(=O)n(C)c2nc(SCC(=O)c3ccccc3)n(CCCc4ccccc4)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J17 compound treatment 1296585.0 537000.0 1.14 1390457.0 652000.0 1.48 1.8531 0.9915 3022590 ChemDiv3_003383 CC1(C)CC(=O)C(=CNc2cccc(NC3=C(C#N)C(=O)CC(C)(C)C3)c2)C(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J18 compound treatment 685063.0 -74500.0 -0.16 635444.0 -103000.0 -0.23 -0.2774 -0.9815 3120030 ChemDiv3_003384 CCN(CC)C(=S)SCc1cn2cccnc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J19 compound treatment 1320964.0 561000.0 1.19 1185891.0 447000.0 1.02 1.5608 0.9969 1198374 ChemDiv3_003385 COc1cccc(c1)C(=O)NC2CC(C)(C)NC(C)(C)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J20 compound treatment 1237404.0 478000.0 1.01 1031594.0 293000.0 0.67 1.1874 0.9793 3120031 ChemDiv3_003386 Cc1ccc(CN(CC(=O)NC2CC2)S(=O)(=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J21 compound treatment 1283328.0 524000.0 1.11 1026300.0 288000.0 0.65 1.2478 0.9682 3022623 ChemDiv3_003387 CCOC(=O)c1ccc(cc1)N2N=C(/C(=C/C=C/c3ccco3)/C2=O)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J22 compound treatment 1045997.0 286000.0 0.61 1021303.0 283000.0 0.64 0.884 0.9996 3120032 ChemDiv3_003388 CNC(=O)CN(c1cccc(C)c1C)S(=O)(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J23 mock treatment 1043412.0 284000.0 0.6 1052540.0 314000.0 0.71 0.9303 0.9964 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 J24 mock treatment 1197123.0 438000.0 0.93 966283.0 228000.0 0.52 1.0221 0.9621 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K01 compound treatment 1184742.0 425000.0 0.9 582125.0 -156000.0 -0.36 0.3859 0.3983 3120169 ChemDiv3_003389 CCOc1ccc(/N=c/2\scc(c3ccc(cc3)S(=O)(=O)N(CC)CC)n2CCCO)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K02 compound treatment 1070258.0 311000.0 0.66 1065698.0 327000.0 0.74 0.9917 0.9982 1658725 ChemDiv3_003390 C1C2CC3CC1CC(C2)(C3)c4cc5ccccc5[nH]4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K03 compound treatment 988318.0 229000.0 0.48 1052922.0 314000.0 0.71 0.8483 0.9821 1415577 ChemDiv3_003391 CCCOc1ccc(CNC(=S)NCc2ccc(OC(C)C)cc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K04 compound treatment 1024392.0 265000.0 0.56 1178203.0 440000.0 1.0 1.1038 0.9628 1601172 ChemDiv3_003392 Clc1ccc(OC(=O)C2c3ccccc3Oc4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K05 compound treatment 1108908.0 349000.0 0.74 1013495.0 275000.0 0.63 0.9657 0.9964 3120170 ChemDiv3_003393 O=C(Oc1cccc2cccnc12)c3cn(nc3c4ccccc4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K06 compound treatment 1203815.0 444000.0 0.94 1160220.0 422000.0 0.96 1.3439 1.0 1273524 ChemDiv3_003394 CC(=O)OC1C(OC(=O)C)N(C(=O)C)C(=O)N1C(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K07 compound treatment 1451671.0 692000.0 1.47 1181923.0 443000.0 1.01 1.7503 0.9832 1721819 ChemDiv3_003395 CCOC(=O)c1sc(C)c2C(=O)NC(C)(Nc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K08 compound treatment 1365527.0 606000.0 1.28 1170340.0 432000.0 0.98 1.6026 0.9912 3022632 ChemDiv3_003396 CCOC(=O)Cn1cc(F)c(=O)[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K09 compound treatment 1136062.0 377000.0 0.8 1075143.0 337000.0 0.77 1.1055 0.9998 1853144 ChemDiv3_003397 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4nc[nH]n4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K10 compound treatment 1351899.0 592000.0 1.26 1566811.0 828000.0 1.88 2.2195 0.9806 3120171 ChemDiv3_003398 C=CCN1C(=O)/C(=c/2\sc3nc(nn3c2=O)c4ccccc4)/c5ccccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K11 compound treatment 1450920.0 691000.0 1.47 1752681.0 1010000.0 2.31 2.6668 0.9761 1685244 ChemDiv3_003399 CC(C)c1ccc(C)cc1OCC(=O)Nc2cc(ccc2C)c3nc4ncccc4o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K12 compound treatment 1187063.0 428000.0 0.91 1495354.0 757000.0 1.72 1.8575 0.9552 3120172 ChemDiv3_003400 FC(F)(F)c1cccc(NC(NC(=O)c2cccs2)C(=O)c3ccccc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K13 compound treatment 1170850.0 411000.0 0.87 1086626.0 348000.0 0.79 1.1761 0.9988 3022674 ChemDiv3_003401 CN(C)c1cccc2c(/C=N/O)ccc(N(C)C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K14 compound treatment 1334209.0 575000.0 1.22 1544564.0 806000.0 1.83 2.1572 0.9803 1204566 ChemDiv3_003402 COc1cccc(c1)C(=O)N2C(C)CC(Nc3ccccc3)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K15 compound treatment 1292254.0 533000.0 1.13 1324560.0 586000.0 1.33 1.7406 0.9966 3120173 ChemDiv3_003403 O=S1(=O)CCC(C1)/N=C/c2cn(nc2c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K16 compound treatment 1533226.0 774000.0 1.64 1222452.0 484000.0 1.1 1.9377 0.9811 3022677 ChemDiv3_003404 Cc1cc(C)nc(N/C(=N\C(=O)Nc2cccc(Cl)c2)/Nc3ccccc3C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K17 compound treatment 1269834.0 510000.0 1.08 1265813.0 527000.0 1.2 1.6126 0.9987 1257823 ChemDiv3_003405 Cc1ccc(cc1)S(=O)(=O)N2CCN(C2)S(=O)(=O)c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K18 compound treatment 1022177.0 263000.0 0.56 1252493.0 514000.0 1.17 1.2199 0.9425 3022679 ChemDiv3_003406 Cc1nnc(Sc2nc(Nc3ccccc3)nc(Nc4ccccc4)n2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K19 compound treatment 1551905.0 792000.0 1.68 1127574.0 389000.0 0.88 1.8132 0.9551 3120174 ChemDiv3_003407 CCOC(=O)CN1C(=O)S/C(=C/c2ccc3n(C)c(=O)n(C)c3c2)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K20 compound treatment 1450812.0 691000.0 1.47 1148743.0 410000.0 0.93 1.6957 0.9762 3022681 ChemDiv3_003408 COc1ccccc1/C=C/c2ccccc2OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K21 compound treatment 1449809.0 690000.0 1.46 1100384.0 362000.0 0.82 1.6164 0.9629 1498680 ChemDiv3_003409 CC1(C)CC(=O)c2c(C1)oc3ccc(NS(=O)(=O)c4ccc5ccccc5c4)cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K22 compound treatment 1299489.0 540000.0 1.14 1099525.0 361000.0 0.82 1.3897 0.9867 1249568 ChemDiv3_003410 CCOC(=O)c1ccc2C(=O)N(C3CCCCC3)C(=O)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K23 mock treatment 1114209.0 355000.0 0.75 996549.0 258000.0 0.59 0.9464 0.9925 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 K24 mock treatment 815630.0 56100.0 0.12 649778.0 -88800.0 -0.2 -0.0586 -0.2504 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L01 compound treatment 506282.0 -253000.0 -0.54 672510.0 -66000.0 -0.15 -0.4858 -0.8714 3120175 ChemDiv3_003411 FC(F)(F)c1cc(nc(SCC2COc3ccccc3O2)c1C#N)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L02 compound treatment 598575.0 -161000.0 -0.34 812194.0 73700.0 0.17 -0.1229 -0.3233 1425939 ChemDiv3_003412 CCOC(=O)c1c(C)oc2c1c(C(N3CCOCC3)c4ccc(OC)cc4)c(O)c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L03 compound treatment 908891.0 149000.0 0.32 1063164.0 325000.0 0.74 0.7457 0.9286 3022724 ChemDiv3_003413 COc1cccc(c1)C(=O)NC(=S)Nc2ccc(O)c(c2)c3nc4ccccc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L04 compound treatment 879174.0 120000.0 0.25 1014318.0 276000.0 0.63 0.6227 0.9206 1551789 ChemDiv3_003414 CCOC(=O)c1c(C)oc2c1c(CN3CCN(CC3)c4ccccc4F)c(O)c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L05 compound treatment 501104.0 -258000.0 -0.55 478724.0 -260000.0 -0.59 -0.8051 -0.9993 1695085 ChemDiv3_003415 Cc1cc(C)cc(Oc2coc3c(CN4CCCCCC4)c(O)ccc3c2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L06 compound treatment 1081854.0 322000.0 0.68 1059588.0 321000.0 0.73 0.9993 0.9995 1264677 ChemDiv3_003416 CC1(C)CC(=O)c2cc(C#N)c(SCSc3nc4CC(C)(C)CC(=O)c4cc3C#N)nc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L07 compound treatment 1031596.0 272000.0 0.58 1066954.0 328000.0 0.75 0.9358 0.9919 3022730 ChemDiv3_003417 CNC(=S)N(Cc1ccccc1)Cc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L08 compound treatment 1039321.0 280000.0 0.59 1078559.0 340000.0 0.77 0.966 0.9914 1376336 ChemDiv3_003418 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3ccc4NC(=O)c5cccc3c45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L09 compound treatment 1378344.0 619000.0 1.31 1158682.0 420000.0 0.96 1.603 0.9879 3022732 ChemDiv3_003419 CC1(C)N(O)C([N+](=C1c2ccccc2)[O-])c3ccc(Br)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L10 compound treatment 1372541.0 613000.0 1.3 1232658.0 494000.0 1.12 1.7133 0.9974 1170952 ChemDiv3_003420 CC1CCCCN1S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc5ccccc5c4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L11 compound treatment 1482705.0 723000.0 1.53 1427936.0 689000.0 1.57 2.1923 0.9999 1148202 ChemDiv3_003421 OC(=O)C(c1c(O)c2ccccc2oc1=O)c3c(O)c4ccccc4oc3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L12 compound treatment 1017413.0 258000.0 0.55 933025.0 194000.0 0.44 0.6992 0.9945 1446893 ChemDiv3_003422 CC1CCCCN1S(=O)(=O)c2ccc(cc2)C(=O)Nc3cccc(c3)c4nc5ccccc5[nH]4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L13 compound treatment 1513990.0 754000.0 1.6 1366377.0 628000.0 1.43 2.1403 0.9984 1283305 ChemDiv3_003423 CC(Cc1c[nH]c2ccccc12)NC(=O)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L14 compound treatment 1496628.0 737000.0 1.56 1419495.0 681000.0 1.55 2.1996 1.0 1042488 ChemDiv3_003424 Nc1cc(=O)[nH]c(=O)n1Cc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L15 compound treatment 1348440.0 589000.0 1.25 1233276.0 495000.0 1.12 1.6781 0.9986 3022737 ChemDiv3_003425 O=C1CCCN1CN2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L16 compound treatment 1415393.0 656000.0 1.39 1277622.0 539000.0 1.23 1.8498 0.998 3120176 ChemDiv3_003426 O=C(CSc1nnc2ccccn12)Nc3ccc4ccccc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L17 compound treatment 1163374.0 404000.0 0.86 1167591.0 429000.0 0.98 1.2951 0.9979 1376805 ChemDiv3_003427 CC1(C)CC(=O)c2c(N)n(nc2C1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L18 compound treatment 1367885.0 608000.0 1.29 1302644.0 564000.0 1.28 1.8188 1.0 1683693 ChemDiv3_003428 N1C(=CC(c2cccs2)n3ncnc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L19 compound treatment 1236434.0 477000.0 1.01 1121305.0 383000.0 0.87 1.3302 0.9972 1148459 ChemDiv3_003429 CCn1c2ccccc2c3cc(NC(=O)C(C)C)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L20 compound treatment 1287429.0 528000.0 1.12 982207.0 244000.0 0.55 1.183 0.9474 3120177 ChemDiv3_003430 Brc1ccc(cc1)S(=O)(=O)N(CCc2ccccc2)CC(=O)NC3CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L21 compound treatment 1337509.0 578000.0 1.23 990069.0 252000.0 0.57 1.2707 0.9398 3022799 ChemDiv3_003431 COc1ccc(cc1)c2c(C)oc3cc(OC)ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L22 compound treatment 1006926.0 247000.0 0.52 839430.0 101000.0 0.23 0.533 0.9312 3120178 ChemDiv3_003432 Cc1cccc(N(CC(=O)Nc2ccccc2)S(=O)(=O)C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L23 mock treatment 1014115.0 255000.0 0.54 671873.0 -66700.0 -0.15 0.2744 0.4896 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 L24 mock treatment 756817.0 -2740.0 -0.01 626201.0 -112000.0 -0.26 -0.1847 -0.723 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M01 compound treatment 509084.0 -250000.0 -0.53 567972.0 -171000.0 -0.39 -0.6497 -0.9881 3022801 ChemDiv3_003433 CCn/1c(cs\c1=N/c2ccc(C)cc2)c3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M02 compound treatment 894608.0 135000.0 0.29 1193389.0 455000.0 1.03 0.9337 0.8701 1692578 ChemDiv3_003434 C1C2CC3CC1CC(C2)(C3)c4csc(n4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M03 compound treatment 1078828.0 319000.0 0.68 1197454.0 459000.0 1.04 1.2164 0.978 1182241 ChemDiv3_003435 COc1ccc(cc1)N(C(=O)c2ccccc2)S(=O)(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M04 compound treatment 993035.0 233000.0 0.49 1096583.0 358000.0 0.81 0.9256 0.9716 1022728 ChemDiv3_003436 Cc1ccc(cc1)S(=O)(=O)NC2c3ccccc3Oc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M05 compound treatment 976210.0 217000.0 0.46 1225605.0 487000.0 1.11 1.1078 0.9241 3120179 ChemDiv3_003437 CC1(CC(=Nc2ccccc2N1)c3cccs3)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M06 compound treatment 988559.0 229000.0 0.49 977020.0 238000.0 0.54 0.7267 0.9985 1002478 ChemDiv3_003438 Clc1ccc(Nc2ncnc3n(ncc23)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M07 compound treatment 1084960.0 325000.0 0.69 1352275.0 614000.0 1.4 1.4745 0.9472 1660145 ChemDiv3_003439 CCOC(=O)c1sc(C)c2C(=O)NC(Nc12)c3ccc(cc3)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M08 compound treatment 1124825.0 365000.0 0.77 1139283.0 401000.0 0.91 1.1918 0.9967 1199493 ChemDiv3_003440 Cc1nc2sccn2c1c3csc(Nc4ccc(cc4)C(=O)O)n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M09 compound treatment 828343.0 68800.0 0.15 1021067.0 283000.0 0.64 0.5573 0.8461 1703311 ChemDiv3_003441 Cc1ccc(NC(=O)CSc2nc3sc4CCCCc4c3c(=O)n2CC=C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M10 compound treatment 616179.0 -143000.0 -0.3 562294.0 -176000.0 -0.4 -0.4983 -0.9907 3022808 ChemDiv3_003442 Oc1ccc(/C=C/2\SC(=S)N(CC3CCCO3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M11 compound treatment 883138.0 124000.0 0.26 1307424.0 569000.0 1.29 1.0998 0.8334 1271724 ChemDiv3_003443 Cc1cc(C)c2oc(nc2c1)c3cc(NC(=O)COc4ccccc4C)ccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M12 compound treatment 1036167.0 277000.0 0.59 1498171.0 760000.0 1.73 1.6359 0.8969 3022874 ChemDiv3_003444 Cc1ccc(cc1)c2nn(cc2/C=C/3\SC(=S)N(CCCC(=O)O)C3=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M13 compound treatment 936347.0 177000.0 0.37 1187526.0 449000.0 1.02 0.9868 0.9075 1216346 ChemDiv3_003445 CN(C)c1ccc2COC(=O)c3ccc(N(C)C)c1c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M14 compound treatment 738050.0 -21500.0 -0.05 848706.0 110000.0 0.25 0.1449 0.569 1120750 ChemDiv3_003446 COc1ccc2N(C(=O)C)C(C)(C)c3ssc(=S)c3-c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M15 compound treatment 991939.0 232000.0 0.49 1363051.0 625000.0 1.42 1.3523 0.8998 3117899 ChemDiv3_003447 Oc1ccc(cc1)C2NC(=O)NC(O)(C2C(=O)c3ccccc3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M16 compound treatment 915087.0 156000.0 0.33 1236414.0 498000.0 1.13 1.0336 0.8766 3022878 ChemDiv3_003448 Cc1cc(C)nc(NC(=N)NO)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M17 compound treatment 1134738.0 375000.0 0.8 1328532.0 590000.0 1.34 1.5109 0.9689 1151303 ChemDiv3_003449 Cc1ccc(cc1)C(=O)N2CCN(C2)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M18 compound treatment 1115004.0 355000.0 0.75 1262399.0 524000.0 1.19 1.375 0.9756 1358369 ChemDiv3_003450 C(Oc1cccc2ccccc12)c3nc4ccccc4[nH]3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M19 compound treatment 219924.0 -540000.0 -1.14 279745.0 -459000.0 -1.04 -1.5465 -0.9989 3117900 ChemDiv3_003451 CCOC(=O)CN1C(=O)S/C(=C/c2cc(C)n(c2C)c3cc(C)ccn3)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M20 compound treatment 1069806.0 310000.0 0.66 1166929.0 428000.0 0.97 1.1538 0.9817 1153417 ChemDiv3_003452 Cc1cc(c2cccs2)c3c(N)c(sc3n1)C(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M21 compound treatment 868715.0 109000.0 0.23 861877.0 123000.0 0.28 0.3619 0.9954 1524326 ChemDiv3_003453 CC(NS(=O)(=O)c1ccc(cc1)C(C)(C)C)C2C3CC4CC(C3)CC2C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M22 compound treatment 850372.0 90800.0 0.19 993493.0 255000.0 0.58 0.546 0.8939 1630427 ChemDiv3_003454 CC(C)OC(=O)c1cccc(NC(=O)c2ccc(Br)cc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M23 mock treatment 758711.0 -848.0 0.0 837368.0 98800.0 0.22 0.1576 0.7014 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 M24 mock treatment 627337.0 -132000.0 -0.28 662351.0 -76200.0 -0.17 -0.3207 -0.9732 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N01 compound treatment 535472.0 -224000.0 -0.48 650472.0 -88100.0 -0.2 -0.4775 -0.9262 1576679 ChemDiv3_003455 C(Sc1nnc(c2ccccc2)c(n1)c3ccccc3)C4COc5ccccc5O4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N02 compound treatment 1041746.0 282000.0 0.6 1032637.0 294000.0 0.67 0.8958 0.9985 3117901 ChemDiv3_003456 CCOC(=O)c1c(C)oc-2c1/C(=C/Nc3cccc(C)n3)/C(=O)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N03 compound treatment 1251241.0 492000.0 1.04 1314756.0 576000.0 1.31 1.6634 0.9936 1365406 ChemDiv3_003457 Cc1cc(C)cc(Oc2coc3cc(OC(=O)C4CCCCC4)ccc3c2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N04 compound treatment 1319885.0 560000.0 1.19 1380534.0 642000.0 1.46 1.8721 0.9948 3117902 ChemDiv3_003458 Clc1ccc(cc1)c2nc(/C=N/c3ccccc3)c4ccccn24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N05 compound treatment 678962.0 -80600.0 -0.17 772462.0 33900.0 0.08 -0.0663 -0.3535 3117903 ChemDiv3_003459 CCOC(=O)N1CCN(CC1)C(=O)CCCN2C(=O)/C(=C\c3cccs3)/SC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N06 compound treatment 1212921.0 453000.0 0.96 1268379.0 530000.0 1.2 1.5314 0.9937 3117904 ChemDiv3_003460 COC(=O)C1C(C(=C(NC1=O)SCC(=O)NCc2ccccc2)C#N)c3ccccc3F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N07 compound treatment 1184463.0 425000.0 0.9 1258501.0 520000.0 1.18 1.4729 0.991 3022943 ChemDiv3_003461 CC(N(Cc1ccccc1)C(=S)Nc2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N08 compound treatment 100703.0 -659000.0 -1.4 98883.0 -640000.0 -1.45 -2.016 -0.9998 1661674 ChemDiv3_003462 Clc1ccccc1C(=O)Oc2c(CN3CCOCC3)cc(Cl)c4cccnc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N09 compound treatment 1367028.0 607000.0 1.29 1358769.0 620000.0 1.41 1.9077 0.999 1593593 ChemDiv3_003463 CCC1=NC(N(O)C1(C)C)c2ccccc2OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N10 compound treatment 1266963.0 507000.0 1.08 1333805.0 595000.0 1.35 1.7176 0.9935 1174273 ChemDiv3_003464 CN(Cc1ccccc1)S(=O)(=O)c2ccc(cc2)C(=O)Nc3nc4ccc5ccccc5c4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N11 compound treatment 1253775.0 494000.0 1.05 1346940.0 608000.0 1.38 1.7189 0.9906 1124946 ChemDiv3_003465 CCC(=O)c1cn(c2ccccc12)S(=O)(=O)c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N12 compound treatment 1274538.0 515000.0 1.09 1484597.0 746000.0 1.7 1.9714 0.9773 1374319 ChemDiv3_003466 CC(NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N13 compound treatment 1192135.0 433000.0 0.92 1516379.0 778000.0 1.77 1.8989 0.9532 1187438 ChemDiv3_003467 COc1ccc(OC)c(NC(=O)C2CCCNC2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N14 compound treatment 1145528.0 386000.0 0.82 1546763.0 808000.0 1.84 1.8779 0.9336 1589905 ChemDiv3_003468 CC1=C(C(c2ccc(O)cc2)c3c(N1)[nH]c(=O)[nH]c3=O)C(=O)OCC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N15 compound treatment 1167494.0 408000.0 0.86 1730552.0 992000.0 2.26 2.2063 0.9134 1548201 ChemDiv3_003469 CC(Cn1nnc2ccccc12)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N16 compound treatment 886110.0 127000.0 0.27 1091208.0 353000.0 0.8 0.7567 0.8949 1198691 ChemDiv3_003470 CCOC(=O)c1c(NC(=O)CSc2nnc3ccccn23)scc1c4ccc(OC)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N17 compound treatment 1096702.0 337000.0 0.71 1402443.0 664000.0 1.51 1.5727 0.9417 3117905 ChemDiv3_003471 CC1(C)CC(=O)C(=C2Nc3ccc(cc3N2)C(=O)c4ccccc4)C(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N18 compound treatment 979500.0 220000.0 0.47 1265291.0 527000.0 1.2 1.1765 0.9155 1540618 ChemDiv3_003472 CCOC(=O)N1CCN(CC1)C(=O)CSCC(=O)Nc2nc(cs2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N19 compound treatment 1035750.0 276000.0 0.59 1344866.0 606000.0 1.38 1.3888 0.9273 1143371 ChemDiv3_003473 CCn1c2ccccc2c3cc(NC(=O)COc4ccc(OC)cc4)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N20 compound treatment 1108186.0 349000.0 0.74 1339838.0 601000.0 1.37 1.4893 0.9583 1639873 ChemDiv3_003474 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)NC2CC2)C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N21 compound treatment 1020472.0 261000.0 0.55 825502.0 87000.0 0.2 0.5309 0.9039 1383609 ChemDiv3_003475 CCC(CC)NCc1oc2ccc(Cl)cc2c1c3ccc(OC)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N22 compound treatment 1187414.0 428000.0 0.91 1290400.0 552000.0 1.25 1.5286 0.9873 3023230 ChemDiv3_003476 Cc1cccc(N(CC(=O)N)S(=O)(=O)C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N23 mock treatment 939011.0 179000.0 0.38 1107138.0 369000.0 0.84 0.8616 0.9362 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 N24 mock treatment 971938.0 212000.0 0.45 801639.0 63100.0 0.14 0.4198 0.8884 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O01 compound treatment 479630.0 -280000.0 -0.59 558535.0 -180000.0 -0.41 -0.709 -0.9835 3117906 ChemDiv3_003477 CCOc1ccc(/N=c/2\scc(c3ccc(cc3)S(=O)(=O)N4CCCC4)n2CC)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O02 compound treatment 804359.0 44800.0 0.09 765032.0 26500.0 0.06 0.1098 0.9759 3023233 ChemDiv3_003478 Nc1nc(cs1)C2(CC3CC4C2)CC(C3)CC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O03 compound treatment 1180885.0 421000.0 0.89 1187505.0 449000.0 1.02 1.3534 0.9978 1118743 ChemDiv3_003479 Cc1ccc(cc1)N(C(=O)c2ccccc2C)S(=O)(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O04 compound treatment 1305808.0 546000.0 1.16 1375538.0 637000.0 1.45 1.8429 0.9939 1346452 ChemDiv3_003480 COC(=O)CSc1nc2sc3CCCc3c2c(=O)n1c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O05 compound treatment 141157.0 -618000.0 -1.31 128961.0 -610000.0 -1.39 -1.907 -0.9996 3023234 ChemDiv3_003481 CC[n+]1c(/C=C/2\Sc3ccccc3N2CCO)sc4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O06 compound treatment 316203.0 -443000.0 -0.94 311857.0 -427000.0 -0.97 -1.3505 -0.9999 3022550 ChemDiv3_003482 Cc1cccc(/N=C/C=C2OC(C)(C)C(C)(C)O2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O07 compound treatment 1145991.0 386000.0 0.82 1064129.0 326000.0 0.74 1.1027 0.9987 1137751 ChemDiv3_003483 O=C(Nc1ccc(cc1)c2nc3ncccc3o2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O08 compound treatment 1248340.0 489000.0 1.04 1263007.0 524000.0 1.19 1.5759 0.9976 3117907 ChemDiv3_003484 CCc1cc2c(=O)n(c(SCC(=O)c3ccccc3)nc2s1)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O09 compound treatment 1215231.0 456000.0 0.97 1352319.0 614000.0 1.4 1.6698 0.9839 3117908 ChemDiv3_003485 CCc1cc2c(=O)n(CC=C)c(SCC(=O)c3ccc(C)cc3)nc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O10 compound treatment 1383764.0 624000.0 1.32 1445707.0 707000.0 1.61 2.0726 0.9953 1672847 ChemDiv3_003486 Cc1ccccc1NC(NC(=O)c2ccco2)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O11 compound treatment 1219180.0 460000.0 0.97 1308615.0 570000.0 1.3 1.6055 0.9901 1634367 ChemDiv3_003487 O=C(Nc1cccc(c1)c2nc3ccccc3o2)c4cccc(OCc5ccccc5)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O12 compound treatment 1221125.0 462000.0 0.98 1261381.0 523000.0 1.19 1.5325 0.9953 3022557 ChemDiv3_003488 COc1ccc(cc1)c2nn(cc2C=C3C(=O)CC(C)(C)CC3=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O13 compound treatment 1147560.0 388000.0 0.82 1222591.0 484000.0 1.1 1.3598 0.9897 3117909 ChemDiv3_003489 COc1ccc2NC(=O)/C(=N/O)/c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O14 compound treatment 1255439.0 496000.0 1.05 1515379.0 777000.0 1.77 1.9922 0.9693 1437035 ChemDiv3_003490 CC1CC(Nc2ccccc2C)c3cccc(C)c3N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O15 compound treatment 1107857.0 348000.0 0.74 1500604.0 762000.0 1.73 1.7472 0.9277 3022560 ChemDiv3_003491 CCCNc1nc2ccccn2c(=O)c1/C=C/3\SC(=S)NC3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O16 compound treatment 1197255.0 438000.0 0.93 1451340.0 713000.0 1.62 1.8021 0.965 3118060 ChemDiv3_003492 Nc1nnc(SCC(=O)N2c3ccccc3Sc4ccc(cc24)C(F)(F)F)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O17 compound treatment 1060911.0 301000.0 0.64 1408001.0 669000.0 1.52 1.528 0.9257 1398200 ChemDiv3_003493 CS(=O)(=O)N1CCN(C1)C(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O18 compound treatment 929697.0 170000.0 0.36 1204964.0 466000.0 1.06 1.0049 0.8971 3118061 ChemDiv3_003494 NC1=C(C#N)C(c2c(nn(c2O1)c3ccccc3)c4ccccc4)c5ccc(Cl)cc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O19 compound treatment 1166000.0 406000.0 0.86 1312209.0 574000.0 1.3 1.5315 0.9797 3022592 ChemDiv3_003495 COC(=O)CSc1sc(=S)sc1SCC[n+]2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O20 compound treatment 1046941.0 287000.0 0.61 1086372.0 348000.0 0.79 0.99 0.9917 3022594 ChemDiv3_003496 C/C(=N\n1c(C)cc(C)c(C#N)c1=O)/C=C/c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O21 compound treatment 917857.0 158000.0 0.34 1036400.0 298000.0 0.68 0.7162 0.9475 1248779 ChemDiv3_003497 CC(NS(=O)(=O)c1c(C)cc(C)cc1C)C2C3CC4CC(C3)CC2C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O22 compound treatment 643241.0 -116000.0 -0.25 1159535.0 421000.0 0.96 0.5025 0.5083 1259680 ChemDiv3_003498 CC(C)C1CCC(C)CC1OC(=O)CN2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O23 mock treatment 811139.0 51600.0 0.11 1013783.0 275000.0 0.63 0.5198 0.8183 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 O24 mock treatment 505783.0 -254000.0 -0.54 594540.0 -144000.0 -0.33 -0.6119 -0.9716 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P01 compound treatment 406702.0 -353000.0 -0.75 409209.0 -329000.0 -0.75 -1.0584 -1.0 1241332 ChemDiv3_003499 Brc1cccc(OCc2cccc(c2)C(=O)NN3CCOCC3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P02 compound treatment 534508.0 -225000.0 -0.48 508709.0 -230000.0 -0.52 -0.7068 -0.999 3118062 ChemDiv3_003500 CCOC(=O)c1c(C)oc-2c1/C(=C/NC3CCCC3)/C(=O)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P03 compound treatment 627913.0 -132000.0 -0.28 730469.0 -8070.0 -0.02 -0.2103 -0.7519 1385678 ChemDiv3_003501 CCC(CC)c1nc(Nc2ccccc2)c3ccccc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P04 compound treatment 617997.0 -142000.0 -0.3 750379.0 11800.0 0.03 -0.1932 -0.6411 3118063 ChemDiv3_003502 CCOC(=O)C(C)Sc1nnc(CNC(=O)C2(CC3CC4CC(C3)C2)C4)n1c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P05 compound treatment 834838.0 75300.0 0.16 958756.0 220000.0 0.5 0.4669 0.8885 3022600 ChemDiv3_003503 CCN(CCO)C(=O)CCN1C(=O)/C(=C/c2ccc(OC)c(OC)c2)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P06 compound treatment 538131.0 -221000.0 -0.47 627504.0 -111000.0 -0.25 -0.5104 -0.9577 1357646 ChemDiv3_003504 CCOc1ccc(NC(=O)CSC2=C(C#N)C(C3=C(CC(C)(C)CC3=O)N2)c4cccs4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P07 compound treatment 997868.0 238000.0 0.51 996611.0 258000.0 0.59 0.7721 0.9972 1315615 ChemDiv3_003505 Cc1ccc(NC(=S)N(CCc2ccccc2)Cc3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P08 compound treatment 974644.0 215000.0 0.46 1414658.0 676000.0 1.54 1.4094 0.879 3118064 ChemDiv3_003506 CN1CCN(CC1)/N=C/c2nc(c3ccccc3)n4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P09 compound treatment 1047364.0 288000.0 0.61 1266974.0 528000.0 1.2 1.281 0.9506 3118065 ChemDiv3_003507 Fc1ccccc1CN2C(=O)S/C(=C\c3ccc4OCOc4c3)/C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P10 compound treatment 995509.0 236000.0 0.5 850953.0 112000.0 0.26 0.5344 0.9514 1727777 ChemDiv3_003508 CCCCN(C)S(=O)(=O)c1ccc(cc1)C(=O)Nc2nc3ccc4ccccc4c3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P11 compound treatment 1187403.0 428000.0 0.91 1149041.0 411000.0 0.93 1.3013 0.9999 1646615 ChemDiv3_003509 Clc1ccc(cc1)C(=O)OCc2cccc(COC(=O)c3ccc(Cl)cc3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P12 compound treatment 1145804.0 386000.0 0.82 1142060.0 404000.0 0.92 1.2277 0.9984 1266949 ChemDiv3_003510 CC(NC(=O)CC1(CC2CC3CC(C2)C1)C3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P13 compound treatment 1118815.0 359000.0 0.76 1038428.0 300000.0 0.68 1.0207 0.9985 1141185 ChemDiv3_003511 Cc1ccc2[nH]cc(CCNC(=O)c3ccccc3)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P14 compound treatment 2575394.0 1820000.0 3.85 2626784.0 1890000.0 4.29 5.7576 0.9985 1623182 ChemDiv3_003512 Cn1c(nc2ccccc12)c3cc4ccc(O)c(CN5CCCC5)c4oc3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P15 compound treatment 1197463.0 438000.0 0.93 1593964.0 855000.0 1.94 2.0317 0.9427 3022639 ChemDiv3_003513 CC(C)c1nccn1CCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P16 compound treatment 977188.0 218000.0 0.46 1549601.0 811000.0 1.84 1.6301 0.8576 1601523 ChemDiv3_003514 O=c1n(c2ccccc2)c(=S)[nH]c3scc(c4cccs4)c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P17 compound treatment 1091006.0 331000.0 0.7 1558778.0 820000.0 1.86 1.8155 0.911 3118066 ChemDiv3_003515 CC1(C)CC(=O)C(=CN2CCOCC2)C(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P18 compound treatment 1190322.0 431000.0 0.91 1444983.0 706000.0 1.61 1.7814 0.9642 3022643 ChemDiv3_003516 Cc1cs/c(=N\C(=S)Nc2ccccc2)/n1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P19 compound treatment 1037325.0 278000.0 0.59 1027193.0 289000.0 0.66 0.8804 0.9985 3118067 ChemDiv3_003517 CC(=O)Nc1ccccc1NC(=O)c2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P20 compound treatment 813755.0 54200.0 0.11 888036.0 150000.0 0.34 0.3216 0.8963 1615664 ChemDiv3_003518 Brc1ccc(CN(CC(=O)Nc2ccccc2)S(=O)(=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P21 compound treatment 507544.0 -252000.0 -0.53 498656.0 -240000.0 -0.55 -0.7634 -0.9999 1741961 ChemDiv3_003519 CCOC(=O)c1c(CSc2ccc(C)cc2)n(C)c3cc(Br)c(O)c(CN(C)C)c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P22 compound treatment 930022.0 170000.0 0.36 884373.0 146000.0 0.33 0.49 0.9991 1152994 ChemDiv3_003520 COc1ccccc1N(CC(=O)NCC2CCCO2)S(=O)(=O)c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P23 mock treatment 775492.0 15900.0 0.03 790166.0 51600.0 0.12 0.1069 0.8751 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2010 P24 mock treatment 506028.0 -254000.0 -0.54 516635.0 -222000.0 -0.5 -0.7368 -0.9995 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A01 compound treatment 503581.0 -231000.0 -0.49 450877.0 -269000.0 -0.61 -0.7788 -0.9939 3022646 ChemDiv3_003521 CCN(CC)C(=O)c1ccc(cc1)N(Cc2ccccc2Cl)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A02 compound treatment 490190.0 -244000.0 -0.52 511152.0 -209000.0 -0.47 -0.702 -0.9991 3118068 ChemDiv3_003522 Fc1nc(F)c(F)c(NCCOC(=O)c2ccccc2)c1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A03 compound treatment 740045.0 5570.0 0.01 695277.0 -24800.0 -0.06 -0.0315 -0.547 1531239 ChemDiv3_003523 S=C(NCc1ccccc1)N2CCN(CC2)c3nc(c4ccccc4)c5CCCCc5c3C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A04 compound treatment 298500.0 -436000.0 -0.92 279257.0 -441000.0 -1.0 -1.3622 -0.9992 1218136 ChemDiv3_003524 C=CC[N+]1(CC#Cc2ccccc2)CCCCC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A05 compound treatment 816242.0 81800.0 0.17 707255.0 -12800.0 -0.03 0.102 0.5804 1599397 ChemDiv3_003525 COc1ccc(cc1)N2CCN(CC2)C(=S)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A06 compound treatment 774004.0 39500.0 0.08 664029.0 -56000.0 -0.13 -0.0308 -0.202 3118069 ChemDiv3_003526 C[N+](C)(CCN1C(=O)C2C(C(C=CC2c3ccccc3)c4ccccc4)C1=O)CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A07 compound treatment 844209.0 110000.0 0.23 743408.0 23400.0 0.05 0.2021 0.8468 3022686 ChemDiv3_003527 O=S(=O)(Nc1ccc(CSc2ccccc2)cc1)c3ccc4OCCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A08 compound treatment 572269.0 -162000.0 -0.34 516734.0 -203000.0 -0.46 -0.57 -0.9894 1787354 ChemDiv3_003528 CS(=O)(=O)N(CC(=O)N1CCc2ccccc2C1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A09 compound treatment 419826.0 -315000.0 -0.67 454255.0 -266000.0 -0.6 -0.899 -0.9988 3118070 ChemDiv3_003529 COc1ccc(/N=C/2\C(=O)N3c4c2cc(C)cc4C(=CC3(C)C)C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A10 compound treatment 448697.0 -286000.0 -0.61 733737.0 13700.0 0.03 -0.4064 -0.6699 3022689 ChemDiv3_003530 CCOC(=O)c1cc(C)sc1/N=C/C2C(=O)NC(=S)NC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A11 compound treatment 107488.0 -627000.0 -1.33 168388.0 -552000.0 -1.25 -1.8267 -0.9996 1683008 ChemDiv3_003531 CC(C)c1ccc(cc1)C2=C(O)C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A12 compound treatment 225952.0 -509000.0 -1.08 296726.0 -423000.0 -0.96 -1.4428 -0.9984 1674919 ChemDiv3_003532 O=C(Nc1ccccc1Sc2ncnc3sc4CCCCc4c23)c5cccs5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A13 compound treatment 1057103.0 323000.0 0.68 942297.0 222000.0 0.51 0.8409 0.9889 1258553 ChemDiv3_003533 CCc1ccc(Oc2coc3cc(OC(=O)C(C)C)ccc3c2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A14 compound treatment 424246.0 -310000.0 -0.66 507917.0 -212000.0 -0.48 -0.8061 -0.9884 1515482 ChemDiv3_003534 ON(C1CC(=O)N(C1=O)c2ccc(cc2)N3CCOCC3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A15 compound treatment 545621.0 -189000.0 -0.4 622962.0 -97100.0 -0.22 -0.4392 -0.9606 1334348 ChemDiv3_003535 O=C(Oc1cccc(Nc2ncnc3ccccc23)c1)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A16 compound treatment 539755.0 -195000.0 -0.41 758454.0 38400.0 0.09 -0.2301 -0.5454 3118071 ChemDiv3_003536 O=C/1N(C2CCCCC2)C(=S)S\C1=C/c3c(NCC4CCCO4)nc5ccccn5c3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A17 compound treatment 516934.0 -218000.0 -0.46 540611.0 -179000.0 -0.41 -0.6146 -0.9981 3022693 ChemDiv3_003537 CN1C(=O)NC(C2=C1CC(C)(C)CC2=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A18 compound treatment 326773.0 -408000.0 -0.86 341907.0 -378000.0 -0.86 -1.2191 -1.0 1298375 ChemDiv3_003538 CC(=O)N1CCN(CC1)C2C(NS(=O)(=O)c3ccc(Cl)cc3)c4cccc5cccc2c45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A19 compound treatment 551400.0 -183000.0 -0.39 692686.0 -27400.0 -0.06 -0.3184 -0.8101 1788606 ChemDiv3_003539 Clc1ccc(CNC(=O)C2c3ccccc3Oc4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A20 compound treatment 520886.0 -214000.0 -0.45 670774.0 -49300.0 -0.11 -0.3994 -0.8562 1872134 ChemDiv3_003540 Cc1ccc(Oc2cc(C#N)c3ccccc3n2)c(c1)n4nc5ccccc5n4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A21 compound treatment 502459.0 -232000.0 -0.49 627984.0 -92100.0 -0.21 -0.4958 -0.9275 3022649 ChemDiv3_003541 CC(C)C(=O)N1N=C2CCCCC2C1(O)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A22 compound treatment 310610.0 -424000.0 -0.9 373360.0 -347000.0 -0.79 -1.1927 -0.9979 1372518 ChemDiv3_003542 CN(C)c1c2CCCc2c(C#N)c3nc4ccccc4n13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A23 mock treatment 428798.0 -306000.0 -0.65 508492.0 -212000.0 -0.48 -0.7983 -0.9892 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 A24 mock treatment 456340.0 -278000.0 -0.59 461379.0 -259000.0 -0.59 -0.8328 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B01 compound treatment 621365.0 -113000.0 -0.24 794553.0 74500.0 0.17 -0.0498 -0.1695 1153643 ChemDiv3_003543 CC(C)c1cc(O)n2c3ccccc3nc2c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B02 compound treatment 688018.0 -46500.0 -0.1 806802.0 86800.0 0.2 0.0698 0.3168 1581286 ChemDiv3_003544 Oc1ccc2c(=O)c(coc2c1CN(CC=C)CC=C)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B03 compound treatment 145659.0 -589000.0 -1.25 177844.0 -542000.0 -1.23 -1.7543 -1.0 1464911 ChemDiv3_003545 CC(C)Nc1ccc(Nc2ccnc3cc4ccccc4cc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B04 compound treatment 732582.0 -1890.0 0.0 899655.0 180000.0 0.41 0.2859 0.7001 3118203 ChemDiv3_003546 COC(=O)c1cccc(/N=C/2\NC(=N)c3ccccc23)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B05 compound treatment 735514.0 1040.0 0.0 852763.0 133000.0 0.3 0.2149 0.7122 1377576 ChemDiv3_003547 COc1cc(NC(=O)COc2ccc(F)cc2)nc(OC)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B06 compound treatment 801019.0 66500.0 0.14 943746.0 224000.0 0.51 0.4594 0.8704 3118204 ChemDiv3_003548 c1csc(c1)c2nc(no2)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B07 compound treatment 942894.0 208000.0 0.44 996538.0 276000.0 0.63 0.7569 0.9851 3118205 ChemDiv3_003549 CC(/N=C/1\CCCc2ccccc2N1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B08 compound treatment 891367.0 157000.0 0.33 995777.0 276000.0 0.63 0.6785 0.956 1556957 ChemDiv3_003550 CC(C)CCNc1ncnc2c3cc4COC(C)(C)Cc4nc3sc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B09 compound treatment 652067.0 -82400.0 -0.17 697751.0 -22300.0 -0.05 -0.1594 -0.8761 3022697 ChemDiv3_003551 OC(=O)c1ccc(COc2ccccc2/C=C/3\NC(=O)N(Cc4ccccc4)C3=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B10 compound treatment 936754.0 202000.0 0.43 1001972.0 282000.0 0.64 0.7565 0.9809 3118206 ChemDiv3_003552 Clc1cccc(c1)N/2CCC\C2=N/c3ccc(Br)cc3C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B11 compound treatment 978704.0 244000.0 0.52 945616.0 226000.0 0.51 0.7287 1.0 3022699 ChemDiv3_003553 FC(F)(F)C(NC(=O)OCc1ccccc1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B12 compound treatment 419237.0 -315000.0 -0.67 447984.0 -272000.0 -0.62 -0.9099 -0.9993 3118207 ChemDiv3_003554 COc1cccc(c1)c2nc3cccc4cccc([nH]2)c43 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B13 compound treatment 433634.0 -301000.0 -0.64 463570.0 -256000.0 -0.58 -0.8633 -0.999 1719480 ChemDiv3_003555 S=C(N1CCCC1)c2cn(CCOc3ccccc3)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B14 compound treatment 331209.0 -403000.0 -0.85 372956.0 -347000.0 -0.79 -1.1625 -0.9992 1867694 ChemDiv3_003556 OC(COc1ccc(NC(=O)c2ccccc2)cc1)Cn3c4ccccc4c5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B15 compound treatment 882190.0 148000.0 0.31 986151.0 266000.0 0.61 0.6492 0.953 3118208 ChemDiv3_003557 Fc1ccc(cc1)C2CC(=O)C(=CNCCN3CCNCC3)C(=O)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B16 compound treatment 840605.0 106000.0 0.22 1003888.0 284000.0 0.65 0.6154 0.9005 3022706 ChemDiv3_003558 O=C1CC(CC(=O)C1=CNc2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B17 compound treatment 969758.0 235000.0 0.5 957042.0 237000.0 0.54 0.7337 0.9993 3118209 ChemDiv3_003559 CC1(C)CC(=O)c2cc(C(=O)N3CC[N+](C)(C)CC3)c(=O)n(c4ccc(Cl)cc4)c2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B18 compound treatment 987424.0 253000.0 0.54 1010817.0 291000.0 0.66 0.8466 0.9946 3022709 ChemDiv3_003560 CC1CCc2sc3ncnc(n4nc(C)cc4C)c3c2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B19 compound treatment 843915.0 109000.0 0.23 898551.0 179000.0 0.41 0.451 0.9648 3023520 ChemDiv3_003561 C=CCN1C(=O)NC(=O)/C(=C\c2cn(Cc3ccccc3)c4ccccc24)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B20 compound treatment 427877.0 -307000.0 -0.65 456336.0 -264000.0 -0.6 -0.8835 -0.9992 3023521 ChemDiv3_003562 COc1cccc(c1)C(=O)CN2C3=NCCCN3c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B21 compound treatment 215922.0 -519000.0 -1.1 254629.0 -465000.0 -1.06 -1.5255 -0.9998 1225293 ChemDiv3_003563 CCOC(=O)c1cnc2ccc(cc2c1N3CC4(C)CC3CC(C)(C)C4)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B22 compound treatment 818191.0 83700.0 0.18 814998.0 95000.0 0.22 0.2781 0.9953 3023522 ChemDiv3_003564 Clc1snc(C(=O)Nc2ccc(I)cc2)c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B23 mock treatment 778088.0 43600.0 0.09 749936.0 29900.0 0.07 0.1134 0.9885 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 B24 mock treatment 501226.0 -233000.0 -0.49 514486.0 -206000.0 -0.47 -0.6801 -0.9996 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C01 compound treatment 410311.0 -324000.0 -0.69 487987.0 -232000.0 -0.53 -0.859 -0.9915 3023523 ChemDiv3_003565 COc1ccccc1N(CC(=O)NC2CC3CCC2C3)S(=O)(=O)c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C02 compound treatment 603246.0 -131000.0 -0.28 649001.0 -71000.0 -0.16 -0.3109 -0.9665 1788093 ChemDiv3_003566 CC(CS(=O)(=O)c1ccc(C)cc1S(=O)(=O)CC(C)N2CCOCC2)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C03 compound treatment 825116.0 90600.0 0.19 803565.0 83500.0 0.19 0.2701 1.0 1737011 ChemDiv3_003567 CC(C)c1nc(N2CCN(CC2)C(=S)NC3CCCCC3)c(C#N)c4CCCCc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C04 compound treatment 214953.0 -520000.0 -1.1 271014.0 -449000.0 -1.02 -1.5007 -0.9993 3023524 ChemDiv3_003568 C[N+](C)(CC=C)CC#Cc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C05 compound treatment 824568.0 90100.0 0.19 767450.0 47400.0 0.11 0.2113 0.9633 3118210 ChemDiv3_003569 COc1ccccc1N(CC(=O)Nc2ccccc2)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C06 compound treatment 810125.0 75600.0 0.16 835782.0 116000.0 0.26 0.2995 0.9718 1699766 ChemDiv3_003570 C(C1OCc2ccccc2CO1)N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C07 compound treatment 299145.0 -435000.0 -0.92 250402.0 -470000.0 -1.07 -1.4076 -0.9974 3118211 ChemDiv3_003571 CS(=O)(=O)N(Cc1ccccc1Cl)c2ccc(cc2)C(=O)Nc3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C08 compound treatment 737267.0 2790.0 0.01 739026.0 19000.0 0.04 0.0347 0.7966 3118212 ChemDiv3_003572 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N2CCCCCC2)c3ccc(C)c(Cl)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C09 compound treatment 712302.0 -22200.0 -0.05 733212.0 13200.0 0.03 -0.0121 -0.2165 1301544 ChemDiv3_003573 Cc1onc(c1C(=O)NC(C)(C)CO)c2c(Cl)cccc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C10 compound treatment 922615.0 188000.0 0.4 948385.0 228000.0 0.52 0.6491 0.9915 3118213 ChemDiv3_003574 CCOC(=O)c1cc(CC)sc1/N=C/C2C(=O)NC(=S)NC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C11 compound treatment 758453.0 24000.0 0.05 684389.0 -35700.0 -0.08 -0.0214 -0.2234 1870864 ChemDiv3_003575 CC(C)c1ccc(cc1)C2C3=C(NC4=C2C(=O)CCC4)c5ccccc5C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C12 compound treatment 993531.0 259000.0 0.55 1067533.0 347000.0 0.79 0.947 0.9842 1314792 ChemDiv3_003576 Cc1cc(=O)oc2cc(OCC(=O)NCc3cccnc3)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C13 compound treatment 1082279.0 348000.0 0.74 1239068.0 519000.0 1.18 1.3558 0.9744 1372263 ChemDiv3_003577 CCc1ccc(Oc2coc3cc(OC(=O)c4ccco4)ccc3c2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C14 compound treatment 896191.0 162000.0 0.34 870433.0 150000.0 0.34 0.4842 1.0 3023525 ChemDiv3_003578 CC/N=C/1\SC(CC(=O)Nc2cccc(c2)C(=O)O)C(=O)N1CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C15 compound treatment 239034.0 -495000.0 -1.05 233144.0 -487000.0 -1.11 -1.5254 -0.9997 3118214 ChemDiv3_003579 Cc1cccc(c1)c2nc(NCCCN3CCOCC3)c4ccccc4n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C16 compound treatment 475785.0 -259000.0 -0.55 504137.0 -216000.0 -0.49 -0.7349 -0.9985 3023526 ChemDiv3_003580 CC(C)(C)c1ccc(/C=C/C(=O)Nc2cccnc2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C17 compound treatment 878919.0 144000.0 0.31 738964.0 18900.0 0.04 0.2469 0.7986 1440542 ChemDiv3_003581 CCN1C(=O)NC(C2=C1CCCC2=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C18 compound treatment 929027.0 195000.0 0.41 982377.0 262000.0 0.6 0.7134 0.9838 1435850 ChemDiv3_003582 Cc1cc(C)cc(OC2CCCCC2NS(=O)(=O)c3ccc(Cl)cc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C19 compound treatment 1087897.0 353000.0 0.75 916260.0 196000.0 0.45 0.8452 0.9693 1879422 ChemDiv3_003583 Cc1onc(c1C(=O)n2nnc3ccccc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C20 compound treatment 922480.0 188000.0 0.4 902579.0 183000.0 0.42 0.5753 0.9998 1610175 ChemDiv3_003584 Oc1cc2ccccc2cc1C(=O)OCC(=O)c3ccc(OCc4ccccc4)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C21 compound treatment 785070.0 50600.0 0.11 672322.0 -47700.0 -0.11 -9.0E-4 -0.0057 3023527 ChemDiv3_003585 CCC1=NN(C(=O)COc2ccc(Cl)c(C)c2)C(O)(C1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C22 compound treatment 934845.0 200000.0 0.42 916963.0 197000.0 0.45 0.6169 0.9997 1145589 ChemDiv3_003586 N#Cc1c2CCCc2c(NCCN3CCCCC3)n4c5ccccc5nc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C23 mock treatment 759026.0 24500.0 0.05 749104.0 29100.0 0.07 0.0835 0.993 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 C24 mock treatment 556493.0 -178000.0 -0.38 423005.0 -297000.0 -0.68 -0.7443 -0.9622 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D01 compound treatment 399728.0 -335000.0 -0.71 490073.0 -230000.0 -0.52 -0.8715 -0.9887 3023528 ChemDiv3_003587 CC(=O)NC1C(=O)SC1(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D02 compound treatment 982387.0 248000.0 0.53 927243.0 207000.0 0.47 0.7047 0.9985 1694459 ChemDiv3_003588 CC(C)OC(=O)C(C)Oc1ccc2c(=O)c(coc2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D03 compound treatment 225368.0 -509000.0 -1.08 248593.0 -471000.0 -1.07 -1.5211 -1.0 3023529 ChemDiv3_003589 Oc1ccccc1/C=C/2\SC(=NC2=O)N3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D04 compound treatment 900185.0 166000.0 0.35 1205518.0 485000.0 1.1 1.0289 0.8883 1245012 ChemDiv3_003590 Cc1cccc(Oc2coc3cc(OC(=O)c4cccs4)ccc3c2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D05 compound treatment 2252919.0 1520000.0 3.22 2630995.0 1910000.0 4.34 5.3483 0.9891 3023530 ChemDiv3_003591 Cc1ccc(C#N)c(SCc2nnc(o2)c3ccc(Cl)cc3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D06 compound treatment 903361.0 169000.0 0.36 1030359.0 310000.0 0.71 0.752 0.9506 1788087 ChemDiv3_003592 COc1cc2c(cc1NC(=O)Cc3ccccc3)oc4ccccc42 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D07 compound treatment 1141670.0 407000.0 0.86 1058916.0 339000.0 0.77 1.1552 0.9984 1917902 ChemDiv3_003593 OC(=O)CC/N=C\1/CCCc2ccccc2N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D08 compound treatment 1039564.0 305000.0 0.65 1071486.0 351000.0 0.8 1.0223 0.9945 1538253 ChemDiv3_003594 CC(C)(C)Nc1ncnc2c3cc4COC(C)(C)Cc4nc3sc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D09 compound treatment 704366.0 -30100.0 -0.06 786736.0 66700.0 0.15 0.0621 0.3774 3023531 ChemDiv3_003595 Cc1ccccc1N2C(=O)NC(=O)/C(=C\c3cn(CC(=O)N4CCOCC4)c5ccccc35)/C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D10 compound treatment 981987.0 248000.0 0.52 1085054.0 365000.0 0.83 0.9578 0.9756 3118215 ChemDiv3_003596 Cc1sc2c(c1C)c(=O)n(c3ccccc3)c4nnc(SCC=C)n42 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D11 compound treatment 906812.0 172000.0 0.37 994174.0 274000.0 0.62 0.699 0.9676 3023532 ChemDiv3_003597 FC(F)(F)C(NC(=O)OC1CCCC1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D12 compound treatment 128903.0 -606000.0 -1.28 129470.0 -591000.0 -1.34 -1.8572 -0.9997 3118216 ChemDiv3_003598 Clc1ccc(/C=C/c2nc3cccc4cccc([nH]2)c43)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D13 compound treatment 1020216.0 286000.0 0.61 1161733.0 442000.0 1.0 1.1384 0.9707 1699463 ChemDiv3_003599 S=C(NCCc1c[nH]c2ccccc12)NCCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D14 compound treatment 929979.0 196000.0 0.41 1211183.0 491000.0 1.12 1.0826 0.909 3023533 ChemDiv3_003600 CCOC(=O)C1=C(O)CCN(C)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D15 compound treatment 1150438.0 416000.0 0.88 1030558.0 311000.0 0.71 1.1227 0.9939 3118217 ChemDiv3_003601 Fc1ccc(cc1)C2CC(=O)C(=CNCCN3CCN(CC3)C(=S)Nc4ccccc4)C(=O)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D16 compound treatment 933194.0 199000.0 0.42 1042133.0 322000.0 0.73 0.8157 0.9655 3023534 ChemDiv3_003602 COC(=O)N(C)CC1Cc2ccccc2O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D17 compound treatment 598524.0 -136000.0 -0.29 728901.0 8860.0 0.02 -0.1896 -0.6561 3118351 ChemDiv3_003603 CC1(C)CC(=O)c2cc(C(=O)NCCC3=CCCCC3)c(=O)n(c4ccccc4)c2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D18 compound treatment 1281815.0 547000.0 1.16 1423447.0 703000.0 1.6 1.9513 0.9876 1642387 ChemDiv3_003604 CCCCc1c(C)c(C#N)c2nc3ccccc3n2c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D19 compound treatment 989838.0 255000.0 0.54 894210.0 174000.0 0.4 0.6628 0.9882 3118352 ChemDiv3_003605 CC(C)(C)N1C(=O)NC(=O)/C(=C\c2cn(Cc3ccccc3)c4ccccc24)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D20 compound treatment 203858.0 -531000.0 -1.12 230342.0 -490000.0 -1.11 -1.5827 -1.0 3023535 ChemDiv3_003606 Clc1ccc(Cn2c(NC(=O)C3CCCCC3)nc4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D21 compound treatment 397342.0 -337000.0 -0.71 360067.0 -360000.0 -0.82 -1.0841 -0.9977 1181214 ChemDiv3_003607 CCOC(=O)c1cnc2c(ccc3ccccc32)c1NC4CC(C)(C)NC(C)(C)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D22 compound treatment 802297.0 67800.0 0.14 785616.0 65600.0 0.15 0.2071 0.9998 3023536 ChemDiv3_003608 Cc1ccc(NCc2ccc(Cl)nc2)c(NCc3ccc(Cl)nc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D23 mock treatment 839611.0 105000.0 0.22 736404.0 16400.0 0.04 0.1839 0.8139 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 D24 mock treatment 567015.0 -167000.0 -0.36 396554.0 -323000.0 -0.74 -0.7711 -0.9442 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E01 compound treatment 493983.0 -240000.0 -0.51 633390.0 -86700.0 -0.2 -0.4998 -0.9144 3118353 ChemDiv3_003609 CS(=O)(=O)N(CC(=O)NCc1ccccc1)c2cc(ccc2Cl)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E02 compound treatment 593820.0 -141000.0 -0.3 604621.0 -115000.0 -0.26 -0.3964 -0.998 3023537 ChemDiv3_003610 C=CCN1C(=O)/C(=C/c2c(nc3ccccn3c2=O)N4CCCCC4)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E03 compound treatment 698681.0 -35800.0 -0.08 881266.0 161000.0 0.37 0.2055 0.5491 3118354 ChemDiv3_003611 CCCCc1nc2sc3c(Cl)ncnc3c2c4CC(C)(C)OCc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E04 compound treatment 615901.0 -119000.0 -0.25 720922.0 879.0 0.0 -0.1763 -0.7015 1442521 ChemDiv3_003612 C=CC[N+]1(CC#Cc2ccccc2)CCOCC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E05 compound treatment 705977.0 -28500.0 -0.06 852894.0 133000.0 0.3 0.1709 0.5547 1231207 ChemDiv3_003613 COc1ccccc1N(CC(=O)N2CCN(CC2)c3ccccc3OC)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E06 compound treatment 879261.0 145000.0 0.31 916121.0 196000.0 0.45 0.5323 0.9834 1028555 ChemDiv3_003614 O=C1CCN(Cc2ccccc2)C(=O)N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E07 compound treatment 960606.0 226000.0 0.48 847772.0 128000.0 0.29 0.5443 0.9712 3118355 ChemDiv3_003615 CN1C(=O)/C(=C/c2c(nc3c(C)cccn3c2=O)N4CCCC4)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E08 compound treatment 973041.0 239000.0 0.51 1041028.0 321000.0 0.73 0.8736 0.984 1863421 ChemDiv3_003616 O=C(NCCc1ccccc1)c2cc3c(ccc4ccccc34)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E09 compound treatment 1029976.0 295000.0 0.63 952047.0 232000.0 0.53 0.8159 0.9963 3023538 ChemDiv3_003617 Cc1cc2nc(NC3=NC(O)C=C(CSc4nc5ccccc5[nH]4)N3)nc(C)c2cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E10 compound treatment 1021851.0 287000.0 0.61 1009153.0 289000.0 0.66 0.8956 0.9993 3118356 ChemDiv3_003618 CCOC(=O)c1c(/N=C/C2C(=O)NC(=S)NC2=O)scc1c3ccc(Br)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E11 compound treatment 602738.0 -132000.0 -0.28 761442.0 41400.0 0.09 -0.1309 -0.4442 1870801 ChemDiv3_003619 Cc1ccc(cc1Cl)n2c(=O)oc3ccc(Cl)cc3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E12 compound treatment 1055391.0 321000.0 0.68 1064041.0 344000.0 0.78 1.0341 0.9976 3118357 ChemDiv3_003620 CC(Oc1ccc(Cl)cc1Cl)C(=O)NC2=NN(C(=O)C2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E13 compound treatment 1185723.0 451000.0 0.96 1019581.0 300000.0 0.68 1.158 0.9861 1610886 ChemDiv3_003621 CCc1ccc(Oc2coc3cc(OC(=O)c4cccs4)ccc3c2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E14 compound treatment 1340194.0 606000.0 1.28 1068103.0 348000.0 0.79 1.4675 0.973 3023539 ChemDiv3_003622 Cc1ccc(NC(=O)CC2Sc3ccc(cc3NC2=O)C(F)(F)F)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E15 compound treatment 668662.0 -65800.0 -0.14 664452.0 -55600.0 -0.13 -0.188 -0.9988 3118358 ChemDiv3_003623 COc1cc(/C=N\c2ccc(O)cc2)ccc1OC(=O)CC3SC(=O)NC3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E16 compound treatment 1035017.0 301000.0 0.64 984652.0 265000.0 0.6 0.8759 0.9996 3118359 ChemDiv3_003624 O=C(NC(Nc1sc2CCCCc2c1C#N)C(=O)c3cccs3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E17 compound treatment 1055746.0 321000.0 0.68 1051495.0 331000.0 0.75 1.0145 0.9987 1490011 ChemDiv3_003625 Cc1ccc(CCP(=O)(O)CCC(=O)O)cn1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E18 compound treatment 1186415.0 452000.0 0.96 1009411.0 289000.0 0.66 1.1427 0.9832 3023540 ChemDiv3_003626 OC(=O)c1c(F)c(F)cc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E19 compound treatment 1058190.0 324000.0 0.69 936309.0 216000.0 0.49 0.8329 0.9866 1413652 ChemDiv3_003627 Cc1onc(c1C(=O)NCc2ccc3OCOc3c2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E20 compound treatment 1215347.0 481000.0 1.02 1183169.0 463000.0 1.05 1.4654 0.9999 3023541 ChemDiv3_003628 N#Cc1cc2N(Cc3ccccc3)CCN(Cc4ccccc4)c2cc1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E21 compound treatment 1081373.0 347000.0 0.74 837729.0 118000.0 0.27 0.7092 0.9063 3118360 ChemDiv3_003629 Clc1ccc(cc1)C(=O)/C=C/N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E22 compound treatment 184199.0 -550000.0 -1.17 179929.0 -540000.0 -1.23 -1.6932 -0.9997 1455387 ChemDiv3_003630 CCc1c(C)c(C#N)c2nc3ccccc3n2c1Nc4ccncc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E23 mock treatment 738271.0 3790.0 0.01 819984.0 99900.0 0.23 0.1664 0.7317 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 E24 mock treatment 611429.0 -123000.0 -0.26 549233.0 -171000.0 -0.39 -0.4591 -0.9813 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F01 compound treatment 450738.0 -284000.0 -0.6 553371.0 -167000.0 -0.38 -0.6933 -0.9752 1286483 ChemDiv3_003631 O=c1n(CN2CCCCC2)nc3-c4ccccc4-c5cccc1c53 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F02 compound treatment 589627.0 -145000.0 -0.31 558404.0 -162000.0 -0.37 -0.477 -0.996 1204240 ChemDiv3_003632 CC1CN(Cc2c(O)ccc3c(=O)c(coc23)c4ccccc4)CC(C)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F03 compound treatment 401152.0 -333000.0 -0.71 529499.0 -191000.0 -0.43 -0.806 -0.9724 3023542 ChemDiv3_003633 CCC1(C)NN(C(=S)N1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F04 compound treatment 927696.0 193000.0 0.41 969189.0 249000.0 0.57 0.6902 0.9873 3118361 ChemDiv3_003634 C1C(Nc2nnnn2C1c3cccs3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F05 compound treatment 958174.0 224000.0 0.47 1027714.0 308000.0 0.7 0.83 0.9821 3118362 ChemDiv3_003635 NC(=O)C1CCN(CC1)C(=O)/C(=C/c2ccco2)/NC(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F06 compound treatment 1084533.0 350000.0 0.74 1214217.0 494000.0 1.12 1.3192 0.9797 1239837 ChemDiv3_003636 O=C(CCc1ccccc1)NCc2ccccn2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F07 compound treatment 1126134.0 392000.0 0.83 1154397.0 434000.0 0.99 1.2854 0.9963 3023543 ChemDiv3_003637 C(/N=C/1\CCCCN1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F08 compound treatment 1056724.0 322000.0 0.68 1159491.0 439000.0 1.0 1.1895 0.9828 3118363 ChemDiv3_003638 CC1C(NC(C(C)C1=O)c2ccccc2C)c3ccccc3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F09 compound treatment 1049663.0 315000.0 0.67 907194.0 187000.0 0.43 0.7733 0.9763 3118364 ChemDiv3_003639 C=CCN1C(=O)S/C(=C\c2cn(CC(=O)N3CCOCC3)c4ccccc24)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F10 compound treatment 1081172.0 347000.0 0.73 1262848.0 543000.0 1.23 1.3923 0.9693 3023595 ChemDiv3_003640 CC(C)CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F11 compound treatment 1235754.0 501000.0 1.06 1440154.0 720000.0 1.64 1.9091 0.9781 3023596 ChemDiv3_003641 Cc1cccnc1NC(=O)NC(C)(C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F12 compound treatment 1107157.0 373000.0 0.79 1952909.0 1230000.0 2.8 2.5407 0.8724 3023597 ChemDiv3_003642 C=CCn1c(=O)n(CC=C)c2cccc3cccc1c32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F13 compound treatment 1322322.0 588000.0 1.25 1647740.0 928000.0 2.11 2.3726 0.9685 1391530 ChemDiv3_003643 COc1ccc(NC(=S)NCCc2c[nH]c3ccccc23)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F14 compound treatment 1066454.0 332000.0 0.7 1650803.0 931000.0 2.12 1.994 0.8941 3023598 ChemDiv3_003644 CC(=O)NS(=O)(=O)c1ccc(cc1)c2ccc(/C=C/3\C(=C(C#N)C(=O)N(CCCO)C3=O)C)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F15 compound treatment 854285.0 120000.0 0.25 1193756.0 474000.0 1.08 0.9412 0.8505 3023599 ChemDiv3_003645 Cc1cccc(NC(=S)N(CCCNC2=CC(=O)CC(C)(C)C2)C3CCCCC3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F16 compound treatment 591270.0 -143000.0 -0.3 607652.0 -112000.0 -0.26 -0.3954 -0.9963 1521665 ChemDiv3_003646 Cc1ccc(OCCN2CCN(CC2)c3cc(C)c(C#N)c4nc5ccccc5n34)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F17 compound treatment 1048625.0 314000.0 0.67 920832.0 201000.0 0.46 0.7937 0.983 3023600 ChemDiv3_003647 CCN(CC)CC#CCN1c2ccccc2Sc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F18 compound treatment 664846.0 -69600.0 -0.15 833243.0 113000.0 0.26 0.0776 0.2616 1373357 ChemDiv3_003648 CCCCc1c(C)c(C#N)c2nc3ccccc3n2c1NCCN4CCOCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F19 compound treatment 1062034.0 328000.0 0.69 1066035.0 346000.0 0.79 1.0473 0.9981 3023601 ChemDiv3_003649 CCOC(=O)c1cc(c2ccccc2)n(n1)c3ccccc3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F20 compound treatment 1062315.0 328000.0 0.7 948495.0 228000.0 0.52 0.8587 0.9897 3118365 ChemDiv3_003650 O=C(Nc1nc2ccccc2n1CCN3CCOCC3)C4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F21 compound treatment 1033487.0 299000.0 0.63 908420.0 188000.0 0.43 0.7511 0.9818 3023602 ChemDiv3_003651 CCOC(=O)c1cnc2c(ccc3ccccc32)c1NCCOC(=O)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F22 compound treatment 887524.0 153000.0 0.32 986421.0 266000.0 0.61 0.6577 0.9572 1866848 ChemDiv3_003652 CCOC(=O)CN(C1SC(=O)N(Cc2cccc(c2)C(=O)O)C1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F23 mock treatment 755686.0 21200.0 0.04 895035.0 175000.0 0.4 0.3131 0.782 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 F24 mock treatment 679623.0 -54900.0 -0.12 568108.0 -152000.0 -0.35 -0.3265 -0.8958 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G01 compound treatment 685696.0 -48800.0 -0.1 754540.0 34500.0 0.08 -0.0177 -0.1361 3118366 ChemDiv3_003653 COC(=O)C1=CN(C=C(C1c2ccc(F)cc2)C(=O)OC)c3cccc(c3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G02 compound treatment 1038216.0 304000.0 0.64 1242057.0 522000.0 1.19 1.2945 0.9587 3023603 ChemDiv3_003654 CCNc1nc2ccccn2c(=O)c1/C=C/3\SC(=S)N(CC=C)C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G03 compound treatment 763003.0 28500.0 0.06 1055095.0 335000.0 0.76 0.5814 0.7608 3118367 ChemDiv3_003655 CCCc1nc2sc3c(Cl)ncnc3c2c4CCCCc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G04 compound treatment 842848.0 108000.0 0.23 979134.0 259000.0 0.59 0.579 0.9157 3023604 ChemDiv3_003656 COCN(C#N)c1nc(nc(n1)N(C)C)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G05 compound treatment 1039324.0 305000.0 0.65 1027221.0 307000.0 0.7 0.9508 0.9992 3118368 ChemDiv3_003657 COc1ccc(cc1)S(=O)(=O)N(CC(=O)N)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G06 compound treatment 1116270.0 382000.0 0.81 1051908.0 332000.0 0.75 1.1058 0.9994 3023605 ChemDiv3_003658 COc1ccc(NC(=O)CSc2nc(cc(=O)[nH]2)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G07 compound treatment 990757.0 256000.0 0.54 1034759.0 315000.0 0.72 0.8901 0.9908 3118494 ChemDiv3_003659 CN(C)c1nc2ccccn2c(=O)c1/C=C/3\SC(=S)N(C)C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G08 compound treatment 840218.0 106000.0 0.22 757398.0 37400.0 0.08 0.2186 0.9118 3023606 ChemDiv3_003660 O=C1N=C(SC1=C2CCCC2)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G09 compound treatment 791786.0 57300.0 0.12 869653.0 150000.0 0.34 0.3264 0.9038 3118495 ChemDiv3_003661 NC(=N)/N=c\1/[nH]c(=O)c2ccccc2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G10 compound treatment 1224145.0 490000.0 1.04 1595190.0 875000.0 1.99 2.141 0.954 3023607 ChemDiv3_003662 CCOC(=O)c1cc(C)sc1/N=C/C2C(=O)CCCC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G11 compound treatment 1258430.0 524000.0 1.11 1412906.0 693000.0 1.58 1.8993 0.9854 3118496 ChemDiv3_003663 CCc1ccc(cc1)C2CC(=NN2C(=O)CCCC(=O)O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G12 compound treatment 1344158.0 610000.0 1.29 1662259.0 942000.0 2.14 2.4287 0.9707 1155587 ChemDiv3_003664 COC1(OC(=O)c2ccccc21)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G13 compound treatment 1523971.0 789000.0 1.67 1717412.0 997000.0 2.27 2.7869 0.9888 1357257 ChemDiv3_003665 CCc1ccc(Oc2coc3cc(OC(=O)C4CCCCC4)ccc3c2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G14 compound treatment 1197778.0 463000.0 0.98 1559055.0 839000.0 1.91 2.0433 0.9524 1610546 ChemDiv3_003666 OC(=O)c1cccnc1SC2CC(=O)N(Cc3ccccc3)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G15 compound treatment 1166891.0 432000.0 0.92 1476257.0 756000.0 1.72 1.8639 0.9566 1448429 ChemDiv3_003667 CCOC(=O)Nc1nc2ccc(OC)cc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G16 compound treatment 713216.0 -21300.0 -0.05 645757.0 -74300.0 -0.17 -0.1513 -0.8655 1873982 ChemDiv3_003668 CC(C)OC(=O)C1=C(C)NC(=O)NC1c2cn(nc2c3ccc(OC(C)C)cc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G17 compound treatment 1425912.0 691000.0 1.47 1339325.0 619000.0 1.41 2.0321 0.9998 1605638 ChemDiv3_003669 CN(CP(=O)(O)CN1CCCCC1)C=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G18 compound treatment 358794.0 -376000.0 -0.8 303185.0 -417000.0 -0.95 -1.2333 -0.9963 1298680 ChemDiv3_003670 CCN1C2C(C(=NC2Nc3ccccc13)OC)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G19 compound treatment 1214722.0 480000.0 1.02 1067152.0 347000.0 0.79 1.2779 0.9921 3023608 ChemDiv3_003671 CC(C)(C)C(=O)NC1CCSC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G20 compound treatment 1294745.0 560000.0 1.19 927876.0 208000.0 0.47 1.174 0.9184 3023609 ChemDiv3_003672 CN/1C(=O)CS\C1=N\c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G21 compound treatment 1121934.0 387000.0 0.82 1021413.0 301000.0 0.69 1.0653 0.9959 3118497 ChemDiv3_003673 CCCCC1=NN(C(=O)C2CC2)C(O)(C1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G22 compound treatment 342870.0 -392000.0 -0.83 330651.0 -389000.0 -0.89 -1.213 -0.9995 1600165 ChemDiv3_003674 CCc1c(C)c(C#N)c2nc3ccccc3n2c1N4CCN(CCO)CC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G23 mock treatment 974032.0 240000.0 0.51 882472.0 162000.0 0.37 0.6202 0.9878 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 G24 mock treatment 657752.0 -76700.0 -0.16 723756.0 3710.0 0.01 -0.109 -0.6695 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H01 compound treatment 508859.0 -226000.0 -0.48 657159.0 -62900.0 -0.14 -0.4393 -0.88 3118498 ChemDiv3_003675 CC(C)(C)C1=CC(=O)c2c(O)c(ccc2C1=O)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H02 compound treatment 1059443.0 325000.0 0.69 1060055.0 340000.0 0.77 1.0338 0.9983 1535282 ChemDiv3_003676 CC(C)COC(=O)C(C)Oc1ccc2c(=O)c(coc2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H03 compound treatment 1187074.0 453000.0 0.96 1061632.0 342000.0 0.78 1.2276 0.9945 1658754 ChemDiv3_003677 Cc1ccc(cc1)N2CCN(C2c3cccs3)c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H04 compound treatment 1175816.0 441000.0 0.94 1084080.0 364000.0 0.83 1.2468 0.9981 1871037 ChemDiv3_003678 CCc1ccc(cc1)N2C(=O)CC(Sc3ccccn3)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H05 compound treatment 1135250.0 401000.0 0.85 986506.0 266000.0 0.61 1.0292 0.9863 3118499 ChemDiv3_003679 Brc1ccc(NC(=O)CC2OCCN(Cc3ccccc3)C2=O)c(Br)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H06 compound treatment 1109911.0 375000.0 0.8 1132687.0 413000.0 0.94 1.2262 0.9967 1785758 ChemDiv3_003680 COC(=O)c1cn(C(=O)CCc2ccccc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H07 compound treatment 1789959.0 1060000.0 2.24 1593127.0 873000.0 1.98 2.9858 0.9982 1468921 ChemDiv3_003681 Cc1cc(C)c2c(N)c(sc2n1)C(=O)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H08 compound treatment 944476.0 210000.0 0.45 1176997.0 457000.0 1.04 1.0494 0.9285 3118500 ChemDiv3_003682 O=C(Nc1c2CCCc2nc3CCCCc13)C4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H09 compound treatment 1190447.0 456000.0 0.97 1630898.0 911000.0 2.07 2.1478 0.9398 3118501 ChemDiv3_003683 Cc1ccc(CN2C(=O)N/C(=C\c3cn(CC(=O)N4CCOCC4)c5ccccc35)/C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H10 compound treatment 1516465.0 782000.0 1.66 1794021.0 1070000.0 2.44 2.8988 0.9822 3023610 ChemDiv3_003684 CSc1nc2sc3CCCc3c2c(=O)n1CC(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H11 compound treatment 1505466.0 771000.0 1.63 1636073.0 916000.0 2.08 2.6284 0.9928 3023611 ChemDiv3_003685 Cc1ccc(C)c(OC(=O)NC(C)(C(F)(F)F)C(F)(F)F)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H12 compound treatment 1344254.0 610000.0 1.29 1708325.0 988000.0 2.25 2.5029 0.9655 3118502 ChemDiv3_003686 O=c1n(Cc2ccccc2)c3cccc4cccc(n1Cc5ccccc5)c43 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H13 compound treatment 1058806.0 324000.0 0.69 1966869.0 1250000.0 2.83 2.4906 0.8539 1457236 ChemDiv3_003687 CCOC(=O)c1ccc(NC(=S)NN2CCN(C)CC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H14 compound treatment 1515753.0 781000.0 1.66 1695689.0 976000.0 2.22 2.7396 0.9896 1170967 ChemDiv3_003688 CCOC1(NC(=O)c2ccccc2)C(=CC(=O)C=C1C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H15 compound treatment 1211312.0 477000.0 1.01 1874573.0 1150000.0 2.62 2.5709 0.914 1870851 ChemDiv3_003689 Cc1ccc(NC(=O)CSc2nnc(C3CC3)n2CC=C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H16 compound treatment 1172349.0 438000.0 0.93 1810931.0 1090000.0 2.48 2.4101 0.9101 1633513 ChemDiv3_003690 CCc1c(C)c(C#N)c2nc3ccccc3n2c1N4CCN(Cc5cc(Cl)ccc5OC)CC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H17 compound treatment 1170369.0 436000.0 0.92 1518272.0 798000.0 1.81 1.9367 0.951 1255680 ChemDiv3_003691 CC(C)(C)NC(=O)c1cccc(NC(=O)CCC(=O)O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H18 compound treatment 305297.0 -429000.0 -0.91 391548.0 -328000.0 -0.75 -1.1715 -0.9952 3023612 ChemDiv3_003692 Cc1cc(o[n+]1C)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H19 compound treatment 1240975.0 506000.0 1.07 1099407.0 379000.0 0.86 1.3691 0.9941 3118503 ChemDiv3_003693 CCCOc1ccc(/C=C/C(=O)Nc2ccc(cc2)S(=O)(=O)Nc3ncccn3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H20 compound treatment 1162967.0 428000.0 0.91 940989.0 221000.0 0.5 0.9975 0.961 3023613 ChemDiv3_003694 CCOc1cccc(OCC)c2c(C)[o+]c(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H21 compound treatment 1002452.0 268000.0 0.57 964954.0 245000.0 0.56 0.7954 0.9999 3118504 ChemDiv3_003695 CCOC(=O)c1cnc2c(ccc3ccccc32)c1NCCOC(=O)c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H22 compound treatment 1124869.0 390000.0 0.83 1103866.0 384000.0 0.87 1.2023 0.9996 3023614 ChemDiv3_003696 CCCCS(=O)(=O)N=C1NCN(CN1)C2CCN(Cc3ccccc3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H23 mock treatment 1185943.0 451000.0 0.96 1044664.0 325000.0 0.74 1.1986 0.9918 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 H24 mock treatment 782383.0 47900.0 0.1 690955.0 -29100.0 -0.07 0.0251 0.2067 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I01 compound treatment 1115825.0 381000.0 0.81 1293375.0 573000.0 1.3 1.4934 0.9736 3118505 ChemDiv3_003697 COC(=O)C1=CN(C=C(C1c2cccc(O)c2)C(=O)OC)c3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I02 compound treatment 1095755.0 361000.0 0.77 1164050.0 444000.0 1.01 1.2554 0.9907 3023615 ChemDiv3_003698 CNc1nc2ccccn2c(=O)c1/C=C/3\SC(=S)N(C)C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I03 compound treatment 956019.0 222000.0 0.47 1147806.0 428000.0 0.97 1.0198 0.9442 1485518 ChemDiv3_003699 CCCc1nc2sc3c(ncnc3c2c4CCCCc14)N5CCCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I04 compound treatment 726828.0 -7650.0 -0.02 906442.0 186000.0 0.42 0.2882 0.6796 1560479 ChemDiv3_003700 CN(C)C(=S)N(C#N)c1nc(nc(n1)N(C)C)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I05 compound treatment 1098711.0 364000.0 0.77 1110427.0 390000.0 0.89 1.1736 0.9976 3118506 ChemDiv3_003701 CCOc1ccc(cc1)N(C(C)C(=O)NCc2ccc(C)cc2)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I06 compound treatment 1391834.0 657000.0 1.39 1243919.0 524000.0 1.19 1.8276 0.9969 3118507 ChemDiv3_003702 COc1cccc(OCCSc2nc(cc(=O)[nH]2)c3ccccc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I07 compound treatment 1143572.0 409000.0 0.87 1142023.0 422000.0 0.96 1.2916 0.9987 3023616 ChemDiv3_003703 C=CCN1C(=O)/C(=C/c2c(Sc3ccccc3)nc4ccccn4c2=O)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I08 compound treatment 1451052.0 717000.0 1.52 1522694.0 803000.0 1.82 2.3645 0.9958 3118508 ChemDiv3_003704 CCOc1ccc(cc1)c2n[nH]c(=S)n2C3CCCC=C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I09 compound treatment 1297255.0 563000.0 1.19 1542658.0 823000.0 1.87 2.1661 0.9764 3023617 ChemDiv3_003705 CSc1nc(c2ccccc2)c3cc(Cl)ccc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I10 compound treatment 1575946.0 841000.0 1.78 1926872.0 1210000.0 2.74 3.2015 0.9783 3118509 ChemDiv3_003706 CCOC(=O)c1c(CC(C)C)csc1/N=C/C2C(=O)CCCC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I11 compound treatment 1118057.0 384000.0 0.81 1279938.0 560000.0 1.27 1.4751 0.9766 1633966 ChemDiv3_003707 CCCOc1ccc(cc1)C(=O)Nc2ccc(NC(=O)c3ccco3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I12 compound treatment 1196742.0 462000.0 0.98 1386676.0 667000.0 1.52 1.7647 0.9777 1787094 ChemDiv3_003708 CCOC(=O)C(C1CCCCC1)C(=O)Nc2cccc(C)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I13 compound treatment 1385172.0 651000.0 1.38 1638864.0 919000.0 2.09 2.4526 0.9797 1440221 ChemDiv3_003709 CCc1ccc(Oc2coc3cc(OC(C)C(=O)OC(C)C)ccc3c2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I14 compound treatment 1552419.0 818000.0 1.73 1633697.0 914000.0 2.08 2.695 0.996 3023618 ChemDiv3_003710 CCSc1nc(nc2CCCCc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I15 compound treatment 1436966.0 702000.0 1.49 1672166.0 952000.0 2.16 2.5837 0.9833 1433865 ChemDiv3_003711 Clc1ccc(cc1)c2nc(C#N)c(NCCc3ccccc3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I16 compound treatment 1332450.0 598000.0 1.27 1695497.0 975000.0 2.22 2.4646 0.9648 3118635 ChemDiv3_003712 O=C1NC(=O)C(=Cc2cn(CCOc3ccc4OCOc4c3)c5ccccc25)C(=O)N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I17 compound treatment 1571416.0 837000.0 1.77 1630246.0 910000.0 2.07 2.7179 0.9971 1334972 ChemDiv3_003713 NS(=O)(=O)c1ccc2NC(C3CC=CC3c2c1)C4CCC=CC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I18 compound treatment 858168.0 124000.0 0.26 827536.0 107000.0 0.24 0.3582 0.9994 3118636 ChemDiv3_003714 COC(=O)C1=C(C)N(/C(=C/c2ccc(OC)cc2)/C1=O)c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I19 compound treatment 1331780.0 597000.0 1.27 1269026.0 549000.0 1.25 1.7779 1.0 3023619 ChemDiv3_003715 Cc1cc(Cl)ccc1OCCCC(=O)NC2CCSC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I20 compound treatment 1240732.0 506000.0 1.07 1195601.0 476000.0 1.08 1.5234 1.0 1863329 ChemDiv3_003716 COc1ccc(CCCc2nnc(SCC(=O)NN)o2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I21 compound treatment 1344280.0 610000.0 1.29 1300221.0 580000.0 1.32 1.8468 0.9999 3023620 ChemDiv3_003717 OC1(CC(=NN1C(=O)C2CC2)C3CCCCC3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I22 compound treatment 171237.0 -563000.0 -1.19 146103.0 -574000.0 -1.3 -1.767 -0.999 1139133 ChemDiv3_003718 CCOC(=O)CCc1c(C)c(C#N)c2nc3ccccc3n2c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I23 mock treatment 1074820.0 340000.0 0.72 1178543.0 458000.0 1.04 1.2473 0.9839 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 I24 mock treatment 784029.0 49600.0 0.11 799475.0 79400.0 0.18 0.202 0.9668 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J01 compound treatment 594220.0 -140000.0 -0.3 563795.0 -156000.0 -0.36 -0.4614 -0.9961 1498091 ChemDiv3_003719 OC(=O)c1ccc(Nc2ncnc3n(Cc4ccccc4)ncc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J02 compound treatment 871715.0 137000.0 0.29 974073.0 254000.0 0.58 0.6141 0.9496 1326070 ChemDiv3_003720 O=C(COc1ccc2c(=O)c(coc2c1)c3ccccc3)OC4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J03 compound treatment 1079355.0 345000.0 0.73 1284113.0 564000.0 1.28 1.4238 0.9645 3023670 ChemDiv3_003721 Clc1ccc(cc1)c2nc3SCCCn3c(=O)c2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J04 compound treatment 1140851.0 406000.0 0.86 1046675.0 327000.0 0.74 1.1343 0.9973 1870982 ChemDiv3_003722 Cc1nc(=S)sn1c2nc(Nc3ccc(C)cc3)nc(Nc4ccc(C)cc4)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J05 compound treatment 1198437.0 464000.0 0.98 1022524.0 302000.0 0.69 1.1818 0.9847 1743126 ChemDiv3_003723 Cc1ccc(C)n1c2sc3CCCCc3c2C(=O)Nc4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J06 compound treatment 1152967.0 418000.0 0.89 1067968.0 348000.0 0.79 1.1867 0.9984 1262325 ChemDiv3_003724 CCOc1ccc(Nc2nc(nc(n2)N3CCCCC3)N4CCCCC4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J07 compound treatment 1777763.0 1040000.0 2.21 1274890.0 555000.0 1.26 2.4559 0.9646 3023671 ChemDiv3_003725 Cc1cc(C)c2c(n1)sc3c(=O)n(Cc4ccccc4Cl)nnc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J08 compound treatment 1108476.0 374000.0 0.79 1388600.0 669000.0 1.52 1.6354 0.954 1740377 ChemDiv3_003726 CCCCC(CC)C(=O)Nc1c2CCCc2nc3CCCCc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J09 compound treatment 1122309.0 388000.0 0.82 1192603.0 473000.0 1.07 1.3411 0.9913 3023672 ChemDiv3_003727 Cc1cc(/C=C\2/SC(=O)N(C2=O)c3ccccc3)c(C)n1c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J10 compound treatment 123754.0 -611000.0 -1.29 108584.0 -611000.0 -1.39 -1.8985 -0.9994 1371047 ChemDiv3_003728 CC1CCc2c(C1)sc3nc(NN)n(C)c(=O)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J11 compound treatment 1632232.0 898000.0 1.9 1178269.0 458000.0 1.04 2.0824 0.9598 3023673 ChemDiv3_003729 CC(NC(=O)Nc1ncccn1)(C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J12 compound treatment 2050430.0 1320000.0 2.79 2500136.0 1780000.0 4.05 4.8344 0.9835 3118637 ChemDiv3_003730 CC1=CC(c2ccc(Cl)cc2)n3nc(NC(=O)CCCC(=O)O)nc3N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J13 compound treatment 1945494.0 1210000.0 2.57 967729.0 248000.0 0.56 2.2136 0.8422 1870817 ChemDiv3_003731 O=c1cc(CSc2nc3ccccc3o2)[nH]c(=S)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J14 compound treatment 1874558.0 1140000.0 2.42 1778763.0 1060000.0 2.41 3.4111 1.0 1613843 ChemDiv3_003732 CC1(C)CC2(CCCN(C2)C(=S)Nc3ccccc3)CCO1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J15 compound treatment 1846854.0 1110000.0 2.36 1975992.0 1260000.0 2.86 3.6866 0.9955 1495361 ChemDiv3_003733 NC(=O)c1cc2C(=O)CCCc2n(c3ccccc3)c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J16 compound treatment 1611249.0 877000.0 1.86 2125834.0 1410000.0 3.2 3.5743 0.9667 1259661 ChemDiv3_003734 CCCc1cc(NCCc2ccccc2)n3c4ccccc4nc3c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J17 compound treatment 1891095.0 1160000.0 2.45 2205494.0 1490000.0 3.38 4.1219 0.9876 1705780 ChemDiv3_003735 CC(C)C(=O)Nc1cccc(c1)c2nc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J18 compound treatment 317936.0 -417000.0 -0.88 339464.0 -381000.0 -0.87 -1.2362 -0.9999 3023674 ChemDiv3_003736 CC[n+]1oc(cc1C)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J19 compound treatment 1329825.0 595000.0 1.26 1374248.0 654000.0 1.49 1.9442 0.9967 3118638 ChemDiv3_003737 COc1ccc(OCCCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J20 compound treatment 180949.0 -554000.0 -1.17 183408.0 -537000.0 -1.22 -1.6925 -0.9998 3023675 ChemDiv3_003738 CCOc1cccc(OCC)c2c(C)[n+](C)c(C)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J21 compound treatment 1560886.0 826000.0 1.75 1377528.0 657000.0 1.49 2.2958 0.9969 1594999 ChemDiv3_003739 C=CCOc1ccc2c3CCCc3c(=O)oc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J22 compound treatment 1263857.0 529000.0 1.12 1284432.0 564000.0 1.28 1.7009 0.9978 3118639 ChemDiv3_003740 Cc1ccc(cc1)S(=O)(=O)N=C2NCN(CN2)C3CCN(Cc4ccccc4)CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J23 mock treatment 1124848.0 390000.0 0.83 906427.0 186000.0 0.42 0.8848 0.9517 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 J24 mock treatment 787513.0 53000.0 0.11 804424.0 84400.0 0.19 0.2152 0.9676 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K01 compound treatment 578663.0 -156000.0 -0.33 637400.0 -82600.0 -0.19 -0.3664 -0.9642 1440044 ChemDiv3_003741 Nc1cc(=O)nc(SCC(=O)Nc2ccc(Cl)cn2)n1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K02 compound treatment 571393.0 -163000.0 -0.35 678848.0 -41200.0 -0.09 -0.3107 -0.8674 1668322 ChemDiv3_003742 Cc1cc(C(=S)N2CCOCC2)c(C)n1c3cccc(C)c3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K03 compound treatment 765758.0 31300.0 0.07 993772.0 274000.0 0.62 0.487 0.7781 3023676 ChemDiv3_003743 CCOc1ccc(cc1)N(C(C)C(=O)N(C)Cc2ccccc2)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K04 compound treatment 846452.0 112000.0 0.24 1054404.0 334000.0 0.76 0.7054 0.8857 1685444 ChemDiv3_003744 O=C(NCC1COc2ccccc2O1)c3cc4ccccc4o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K05 compound treatment 974458.0 240000.0 0.51 1140136.0 420000.0 0.96 1.0351 0.9565 3118640 ChemDiv3_003745 CCOC(=O)N1CCN(CC1)C(=O)CN(c2cc(ccc2Cl)C(F)(F)F)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K06 compound treatment 1259721.0 525000.0 1.11 1125223.0 405000.0 0.92 1.4387 0.9956 3023677 ChemDiv3_003746 COc1cccc(NC(=O)CSc2nc(N)cc(=O)[nH]2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K07 compound treatment 1054513.0 320000.0 0.68 947859.0 228000.0 0.52 0.846 0.9911 3118641 ChemDiv3_003747 CN1C(=O)/C(=C/c2c(Sc3ccccc3)nc4ccc(C)cn4c2=O)/SC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K08 compound treatment 468211.0 -266000.0 -0.56 455733.0 -264000.0 -0.6 -0.8241 -0.9995 3023678 ChemDiv3_003748 CC1CC2(CC(C)(C)C1)NN(C(=S)N2)c3nc4ccccc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K09 compound treatment 1489442.0 755000.0 1.6 1280970.0 561000.0 1.28 2.0335 0.9937 1788362 ChemDiv3_003749 O=C(Sc1ccccn1)N2c3ccccc3Sc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K10 compound treatment 1168388.0 434000.0 0.92 1331220.0 611000.0 1.39 1.633 0.9799 3023679 ChemDiv3_003750 CCOC(=O)c1c(/N=C/C2C(=O)CCCC2=O)scc1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K11 compound treatment 1195158.0 461000.0 0.98 1361426.0 641000.0 1.46 1.7217 0.981 3118642 ChemDiv3_003751 OC(=O)c1ccccc1C(=O)n2c(COc3ccc(Cl)cc3Cl)nc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K12 compound treatment 1690393.0 956000.0 2.03 1518960.0 799000.0 1.82 2.7173 0.9985 3023680 ChemDiv3_003752 Cc1nn(c(C)c1Sc2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K13 compound treatment 1617888.0 883000.0 1.87 1584487.0 864000.0 1.97 2.714 0.9997 1193366 ChemDiv3_003753 CCc1ccc(Oc2coc3cc(OC(C)C(=O)OCC(C)C)ccc3c2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K14 compound treatment 1631000.0 897000.0 1.9 1855930.0 1140000.0 2.58 3.17 0.9886 3118643 ChemDiv3_003754 NNC(=O)CSc1nc(nc2CCCCc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K15 compound treatment 1507304.0 773000.0 1.64 1796653.0 1080000.0 2.45 2.8893 0.9809 3023681 ChemDiv3_003755 O=c1[nH]c(SC/C=C/c2ccccc2)nc3sc4CCCc4c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K16 compound treatment 1358447.0 624000.0 1.32 1294234.0 574000.0 1.31 1.8584 1.0 3118644 ChemDiv3_003756 COc1ccccc1OCCSc2nc(c([nH]2)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K17 compound treatment 1204559.0 470000.0 1.0 1082477.0 362000.0 0.82 1.2873 0.9955 3023682 ChemDiv3_003757 CC1(C)C(OC(=O)C2(CCCCC2)C1=O)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K18 compound treatment 660607.0 -73900.0 -0.16 576716.0 -143000.0 -0.33 -0.3412 -0.9436 3118645 ChemDiv3_003758 COC(=O)C1=C(C)N/C(=C/c2ccccc2OC)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K19 compound treatment 1522539.0 788000.0 1.67 1046244.0 326000.0 0.74 1.7057 0.9332 3118646 ChemDiv3_003759 Cc1cc2ncn(C(=O)CCCOc3ccccc3)c2cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K20 compound treatment 1352940.0 618000.0 1.31 1084040.0 364000.0 0.83 1.5123 0.9754 1319748 ChemDiv3_003760 COc1ccc(CCCc2nnc(S)o2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K21 compound treatment 1374940.0 640000.0 1.36 1102715.0 383000.0 0.87 1.5753 0.9769 3118647 ChemDiv3_003761 COc1ccc(CC(=O)N2N=C(CC2(O)C(C)(C)C)C(F)(F)F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K22 compound treatment 820890.0 86400.0 0.18 759826.0 39800.0 0.09 0.1935 0.9471 1425470 ChemDiv3_003762 CC(=O)Nc1ccc(Nc2c3CCCCc3c(C#N)c4nc5ccccc5n24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K23 mock treatment 947067.0 213000.0 0.45 933073.0 213000.0 0.48 0.6612 0.9994 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 K24 mock treatment 649220.0 -85300.0 -0.18 597201.0 -123000.0 -0.28 -0.3253 -0.9778 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L01 compound treatment 431856.0 -303000.0 -0.64 550610.0 -169000.0 -0.39 -0.726 -0.9702 3118648 ChemDiv3_003763 CCOc1ccc(N/C=C/C2=[O+]C(C)(C)C(C)(C)O2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L02 compound treatment 499544.0 -235000.0 -0.5 723849.0 3810.0 0.01 -0.3461 -0.6947 1148259 ChemDiv3_003764 CCOC(=O)c1cnc2ccc(C)cc2c1Nc3ccc(cc3)N4CCOCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L03 compound treatment 733800.0 -676.0 0.0 1053674.0 334000.0 0.76 0.5353 0.7058 1668601 ChemDiv3_003765 CCOc1ccc(cc1)N2C(=O)c3ccccc3NC2(CC)CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L04 compound treatment 615790.0 -119000.0 -0.25 853500.0 133000.0 0.3 0.0366 0.0929 1871007 ChemDiv3_003766 CC1CC(C)(C)N(C(=O)CSc2nc(C)cc(C)n2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L05 compound treatment 854243.0 120000.0 0.25 1139960.0 420000.0 0.95 0.8546 0.8651 3118649 ChemDiv3_003767 Cc1ccc(cc1)N2C(=O)C(/C=N/Cc3ccc(cc3)C(=O)O)C(=O)NC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L06 compound treatment 1017360.0 283000.0 0.6 1214733.0 495000.0 1.12 1.2193 0.9566 1409959 ChemDiv3_003768 CCOc1nc(NC(C)(C)CO)nc(OCC)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L07 compound treatment 267002.0 -467000.0 -0.99 291914.0 -428000.0 -0.97 -1.389 -1.0 3023683 ChemDiv3_003769 O=c1c(cc2[nH]c3ccccc3c2n1c4ccccc4)[n+]5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L08 compound treatment 151452.0 -583000.0 -1.24 149831.0 -570000.0 -1.3 -1.7907 -0.9997 1287509 ChemDiv3_003770 CCCn1c2CCCc2c(=N)c3CCCc31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L09 compound treatment 959719.0 225000.0 0.48 1161551.0 442000.0 1.0 1.0474 0.9423 3118791 ChemDiv3_003771 Cc1ccc(/N=C/2\NC(=O)\C(=C/c3ccc4n(C)c(=O)n(C)c4c3)\S2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L10 compound treatment 1331642.0 597000.0 1.27 1308406.0 588000.0 1.34 1.841 0.9996 3023684 ChemDiv3_003772 CCOC(=O)c1sc(nc1C)N2N=C(C)/C(=C\c3ccco3)/C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L11 compound treatment 1043858.0 309000.0 0.66 1360581.0 641000.0 1.46 1.4935 0.9351 1686077 ChemDiv3_003773 CCOc1cc(ccc1OCc2ccccc2F)C(=S)N3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L12 compound treatment 1045861.0 311000.0 0.66 1238332.0 518000.0 1.18 1.3 0.9625 3023685 ChemDiv3_003774 O=C(Nc1nc2nc(cc(c3ccccc3)n2n1)c4ccccc4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L13 compound treatment 1298422.0 564000.0 1.2 1451324.0 731000.0 1.66 2.021 0.9869 3118792 ChemDiv3_003775 COc1cc(NC=C2C(=O)c3ccccc3C2=O)cc(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L14 compound treatment 1167643.0 433000.0 0.92 1092683.0 373000.0 0.85 1.2484 0.9992 3118793 ChemDiv3_003776 COc1ccc(/C=C/C(=O)NCC2(CCOCC2)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L15 compound treatment 1346358.0 612000.0 1.3 1446113.0 726000.0 1.65 2.0845 0.9929 3023686 ChemDiv3_003777 COc1ccc(cc1)n2c3CC(C)(C)CC(=O)c3cc(C(=O)N)c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L16 compound treatment 1165816.0 431000.0 0.91 1347133.0 627000.0 1.43 1.6547 0.977 1339113 ChemDiv3_003778 CCCc1cc(n2cnc3ccccc23)n4c5ccccc5nc4c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L17 compound treatment 1019349.0 285000.0 0.6 1412220.0 692000.0 1.57 1.5398 0.9135 1197106 ChemDiv3_003779 COc1cc2nc(COc3ccccc3)oc(=O)c2cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L18 compound treatment 1072487.0 338000.0 0.72 1475797.0 756000.0 1.72 1.7217 0.9248 1224201 ChemDiv3_003780 CC1CN(CC(C)O1)C(=S)SCC(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L19 compound treatment 1170460.0 436000.0 0.92 1346293.0 626000.0 1.42 1.6603 0.9781 3023687 ChemDiv3_003781 CCCc1nnc2c3c4CCCCc4sc3ncn12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L20 compound treatment 115108.0 -619000.0 -1.31 196722.0 -523000.0 -1.19 -1.7698 -0.9988 3118794 ChemDiv3_003782 CCOc1ccc/c(=N\C2CCCCC2)/c3c(C)n(C)c(C)c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L21 compound treatment 1029330.0 295000.0 0.63 1215863.0 496000.0 1.13 1.2391 0.9613 1403487 ChemDiv3_003783 COC(=O)Oc1ccc2c(=O)c(coc2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L22 compound treatment 932527.0 198000.0 0.42 1187435.0 467000.0 1.06 1.0483 0.9175 3118795 ChemDiv3_003784 NC(=NS(=O)(=O)c1ccc(NC(=O)c2ccco2)cc1)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L23 mock treatment 859788.0 125000.0 0.27 985410.0 265000.0 0.6 0.6145 0.9321 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 L24 mock treatment 556330.0 -178000.0 -0.38 601454.0 -119000.0 -0.27 -0.4577 -0.9864 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M01 compound treatment 579710.0 -155000.0 -0.33 693654.0 -26400.0 -0.06 -0.2744 -0.8228 1167509 ChemDiv3_003785 CCCc1nc(NCc2ccccc2)c(C#N)c3CCCCc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M02 compound treatment 763185.0 28700.0 0.06 1022711.0 303000.0 0.69 0.5296 0.7667 3023688 ChemDiv3_003786 CC(=O)NS(=O)(=O)c1ccc(cc1)c2ccc(/C=C\3/C(=O)NN(C3=O)c4cccc(Cl)c4)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M03 compound treatment 650545.0 -83900.0 -0.18 811318.0 91300.0 0.21 0.0209 0.0765 3118796 ChemDiv3_003787 CCOc1ccc(cc1)S(=O)(=O)N(CC(=O)NCc2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M04 compound treatment 960462.0 226000.0 0.48 996506.0 276000.0 0.63 0.7832 0.991 1306758 ChemDiv3_003788 CC(NC(=O)COc1ccccc1)C2COc3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M05 compound treatment 835181.0 101000.0 0.21 1016080.0 296000.0 0.67 0.6269 0.8878 1714591 ChemDiv3_003789 COc1ccccc1N(CC(=O)NCc2ccco2)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M06 compound treatment 271612.0 -463000.0 -0.98 205813.0 -514000.0 -1.17 -1.5205 -0.9962 1642367 ChemDiv3_003790 Cc1ccc(cc1)N2CCN(C2c3ccncc3)c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M07 compound treatment 1191388.0 457000.0 0.97 1296784.0 577000.0 1.31 1.6121 0.9889 3118797 ChemDiv3_003791 C=CCNc1nc2ccccn2c(=O)c1/C=C/3\SC(=S)N(Cc4ccc5OCOc5c4)C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M08 compound treatment 833697.0 99200.0 0.21 1059199.0 339000.0 0.77 0.694 0.8683 1732117 ChemDiv3_003792 CCC(=O)NC(=S)Nc1cc(ccc1OC)c2nc3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M09 compound treatment 820816.0 86300.0 0.18 968447.0 248000.0 0.56 0.5288 0.8907 1788364 ChemDiv3_003793 Cc1nnc(SC(=O)N2c3ccccc3Sc4ccccc24)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M10 compound treatment 925014.0 191000.0 0.4 1185124.0 465000.0 1.06 1.0333 0.9129 3118798 ChemDiv3_003794 CCOC(=O)c1c(C)c(C)sc1/N=C/C2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M11 compound treatment 929115.0 195000.0 0.41 1119951.0 400000.0 0.91 0.9347 0.9361 1693706 ChemDiv3_003795 OC(=O)c1cccc(c1)N2C(SCC2=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M12 compound treatment 909484.0 175000.0 0.37 1075808.0 356000.0 0.81 0.8343 0.9375 3118799 ChemDiv3_003796 COc1ccc(NC(=O)CC2S/C(=N\c3ccccc3)/N(C2=O)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M13 compound treatment 1082944.0 348000.0 0.74 1351559.0 632000.0 1.44 1.5376 0.9523 1234541 ChemDiv3_003797 CC1CCc2[nH]c3ccc(cc3c2C1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M14 compound treatment 1126427.0 392000.0 0.83 1050614.0 331000.0 0.75 1.119 0.9987 1255457 ChemDiv3_003798 CN(C(=O)Oc1cccc2cccnc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M15 compound treatment 964856.0 230000.0 0.49 1120568.0 401000.0 0.91 0.9892 0.9574 3023739 ChemDiv3_003799 CCOC(=O)c1c(C)c(C)sc1N2C(=O)C3ON(C(C3C2=O)c4ccccc4)c5ccccc5C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M16 compound treatment 1170311.0 436000.0 0.92 1180690.0 461000.0 1.05 1.3939 0.998 3023740 ChemDiv3_003800 CN1C(=O)N(C)C(=O)C(=Cc2cn(Cc3noc(n3)c4ccc(C)cc4)c5ccccc25)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M17 compound treatment 1101381.0 367000.0 0.78 1116251.0 396000.0 0.9 1.187 0.9973 3023741 ChemDiv3_003801 O=C(Nc1ccc(cc1)S(=O)(=O)Nc2nccs2)c3cc(nc4ccccc34)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M18 compound treatment 1039866.0 305000.0 0.65 976026.0 256000.0 0.58 0.8693 0.9986 3023742 ChemDiv3_003802 COC(=O)C1=C(C)N/C(=C/c2cccs2)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M19 compound treatment 871556.0 137000.0 0.29 849645.0 130000.0 0.29 0.4138 1.0 3023743 ChemDiv3_003803 CC1=NN(C(=O)COc2cc(C)cc(C)c2)C(O)(C1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M20 compound treatment 1065216.0 331000.0 0.7 1036723.0 317000.0 0.72 1.0049 0.9999 3118800 ChemDiv3_003804 Sc1nnc(COc2ccc3CCCCc3c2)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M21 compound treatment 765932.0 31500.0 0.07 1107532.0 387000.0 0.88 0.6701 0.7585 3118801 ChemDiv3_003805 COc1ccc(cc1)C2=NN(C(=O)c3ccccc3O)C(O)(C2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M22 compound treatment 941828.0 207000.0 0.44 948851.0 229000.0 0.52 0.6787 0.9965 1363934 ChemDiv3_003806 Cc1nccn1c2c3CCCCc3c(C#N)c4nc5ccccc5n24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M23 mock treatment 801700.0 67200.0 0.14 856159.0 136000.0 0.31 0.3196 0.938 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 M24 mock treatment 612908.0 -122000.0 -0.26 504254.0 -216000.0 -0.49 -0.5291 -0.9548 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N01 compound treatment 456828.0 -278000.0 -0.59 465361.0 -255000.0 -0.58 -0.8256 -1.0 3023744 ChemDiv3_003807 CCOC(=O)c1c(NC(=O)C)no[n+]1[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N02 compound treatment 933729.0 199000.0 0.42 919919.0 200000.0 0.45 0.62 0.9993 1330639 ChemDiv3_003808 CC(C)OC(=O)COc1cc2oc(=O)c3CCCc3c2cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N03 compound treatment 1027970.0 293000.0 0.62 963159.0 243000.0 0.55 0.8308 0.9983 3118802 ChemDiv3_003809 NC(=O)COc1ccc(/C=c\2/sc3nc4ccccc4n3c2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N04 compound treatment 232959.0 -502000.0 -1.06 254810.0 -465000.0 -1.06 -1.4997 -1.0 3023745 ChemDiv3_003810 Cc1c(oc2ccc3c(C)cc(=O)oc3c12)/C(=N/O)/c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N05 compound treatment 316885.0 -418000.0 -0.89 344553.0 -375000.0 -0.85 -1.2296 -0.9998 3118803 ChemDiv3_003811 CCn1c(=N)n(CCOc2ccc(C)cc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N06 compound treatment 1015615.0 281000.0 0.6 1055533.0 335000.0 0.76 0.9608 0.9926 3118804 ChemDiv3_003812 Cc1[nH]nc2OC(=C(C#N)C(c12)c3cc(COc4ccccc4Cl)c(C)cc3C)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N07 compound treatment 1242552.0 508000.0 1.08 1107445.0 387000.0 0.88 1.3844 0.995 1788734 ChemDiv3_003813 Clc1ccc2[nH]c3C(CCCc3c2c1)C(=O)N4CCN(CC4)C(=O)c5ccco5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N08 compound treatment 119196.0 -615000.0 -1.3 112743.0 -607000.0 -1.38 -1.8986 -0.9996 1583570 ChemDiv3_003814 CCCCN1CCc2c1nc3ccc(Br)cc3c2N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N09 compound treatment 1044654.0 310000.0 0.66 1351852.0 632000.0 1.44 1.4807 0.9373 3118805 ChemDiv3_003815 CCOC(=O)Cn1cc(/C=C/2\C(=O)NC(=O)N(C2=O)c3ccc(F)cc3)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N10 compound treatment 1031286.0 297000.0 0.63 1367021.0 647000.0 1.47 1.485 0.9282 3023746 ChemDiv3_003816 CC1SC(=S)N(C1=O)c2ccc(cc2)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N11 compound treatment 1027346.0 293000.0 0.62 1166477.0 446000.0 1.01 1.1567 0.9722 3023747 ChemDiv3_003817 S=C(N1CCCC1)c2c[nH]c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N12 compound treatment 1198981.0 465000.0 0.98 1311806.0 592000.0 1.35 1.6477 0.9882 3118806 ChemDiv3_003818 C1N2CN3CN1CC(C2)(C3)/N=C\c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N13 compound treatment 1241624.0 507000.0 1.08 1277582.0 558000.0 1.27 1.6566 0.9966 3118807 ChemDiv3_003819 COc1cc(N/C(=C\2/C(=NN(C2=O)c3nc4ccccc4s3)C)/C)cc(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N14 compound treatment 988687.0 254000.0 0.54 1217330.0 497000.0 1.13 1.1805 0.9426 1134380 ChemDiv3_003820 CCCCN(C)c1ncnc2c3cc4COC(C)(C)Cc4nc3sc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N15 compound treatment 1058402.0 324000.0 0.69 1326323.0 606000.0 1.38 1.4603 0.9482 3118808 ChemDiv3_003821 Cc1ccc(cc1)n2c3CCCC(=O)c3cc(C(=O)NC4CCSC4=O)c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N16 compound treatment 261175.0 -473000.0 -1.0 207041.0 -513000.0 -1.17 -1.5342 -0.9972 1534750 ChemDiv3_003822 CCN(CC)CCNc1c2CCCCc2c(C#N)c3nc4ccccc4n13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N17 compound treatment 821778.0 87300.0 0.19 1008195.0 288000.0 0.66 0.5941 0.8727 1570102 ChemDiv3_003823 COc1ccc(CC(=O)Nc2cccc(c2)c3nnc(o3)c4ccco4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N18 compound treatment 828576.0 94100.0 0.2 1124691.0 405000.0 0.92 0.7916 0.8409 3118809 ChemDiv3_003824 CCc1nnc(NC(=O)c2ccc(cc2)N3C(=O)C4C5CC(C=C5)C4C3=O)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N19 compound treatment 1328945.0 594000.0 1.26 1431126.0 711000.0 1.62 2.0343 0.9924 1492524 ChemDiv3_003825 O=c1oc(nc2sc3CCCCc3c12)c4cc5ccccc5o4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N20 compound treatment 1198620.0 464000.0 0.98 1125881.0 406000.0 0.92 1.3482 0.9995 3118810 ChemDiv3_003826 CC(CCC(=O)O)C1CC[C@H]2C3CCC4CC(=O)CCC4(C)[C@H]3CC(=O)C12C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N21 compound treatment 1227938.0 493000.0 1.05 1253826.0 534000.0 1.21 1.5978 0.9973 1224438 ChemDiv3_003827 CC(C)COC(=O)C(C)Oc1ccc2c3CCCc3c(=O)oc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N22 compound treatment 1114138.0 380000.0 0.8 1208278.0 488000.0 1.11 1.354 0.9875 3118945 ChemDiv3_003828 CCCCS(=O)(=O)N=C1NCN(Cc2ccco2)CN1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N23 mock treatment 973849.0 239000.0 0.51 1047933.0 328000.0 0.75 0.886 0.9824 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 N24 mock treatment 578714.0 -156000.0 -0.33 614474.0 -106000.0 -0.24 -0.4032 -0.9877 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O01 compound treatment 463027.0 -271000.0 -0.58 561085.0 -159000.0 -0.36 -0.6625 -0.9749 1741234 ChemDiv3_003829 CCCc1nc(NC2CCCCC2)c(C#N)c3CCCCc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O02 compound treatment 941471.0 207000.0 0.44 1045939.0 326000.0 0.74 0.8342 0.9687 3118946 ChemDiv3_003830 Cc1c(/C=N/c2cccc(NC(=O)c3ccccc3)c2)c(O)n4c5ccccc5nc4c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O03 compound treatment 1119015.0 385000.0 0.82 1181210.0 461000.0 1.05 1.3178 0.9923 3023748 ChemDiv3_003831 COc1ccccc1N(CC(=O)N(C)Cc2ccccc2)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O04 compound treatment 1237387.0 503000.0 1.07 1230154.0 510000.0 1.16 1.574 0.9991 3118947 ChemDiv3_003832 COc1ccccc1CC(=O)NCC2OCCc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O05 compound treatment 1066545.0 332000.0 0.7 1139391.0 419000.0 0.95 1.1719 0.9889 1275170 ChemDiv3_003833 CCOc1ccc(cc1)S(=O)(=O)N(CC(=O)N2CCC(C)CC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O06 compound treatment 159972.0 -575000.0 -1.22 163099.0 -557000.0 -1.27 -1.7566 -0.9998 3023749 ChemDiv3_003834 Brc1ccc(cc1)C2=CC(=O)C=CC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O07 compound treatment 1509488.0 775000.0 1.64 1693244.0 973000.0 2.21 2.7263 0.9893 1119910 ChemDiv3_003835 COc1ccc2c(C)c(CC(C)O)c(=O)oc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O08 compound treatment 1292332.0 558000.0 1.18 1308212.0 588000.0 1.34 1.7818 0.9981 3118948 ChemDiv3_003836 CCOC(=O)c1c(/N=C/C2C(=O)NC(=S)NC2=O)sc3CCCCCc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O09 compound treatment 1033144.0 299000.0 0.63 1102460.0 382000.0 0.87 1.0625 0.9879 1870831 ChemDiv3_003837 CCOC(=O)Oc1ccc2N(C(=O)OCC)C(C)(C)C=C(C)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O10 compound treatment 1041604.0 307000.0 0.65 1391962.0 672000.0 1.53 1.5406 0.9277 3118949 ChemDiv3_003838 CCOC(=O)c1cc(CC)sc1/N=C/C2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O11 compound treatment 130184.0 -604000.0 -1.28 146531.0 -574000.0 -1.3 -1.8279 -1.0 1259659 ChemDiv3_003839 Cc1ccc2nc(C)cc(NC3CCCCC3)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O12 compound treatment 1094802.0 360000.0 0.76 1317246.0 597000.0 1.36 1.5002 0.963 1450973 ChemDiv3_003840 CCOc1ccccc1N2C(=O)CC(N(O)c3ccccc3)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O13 compound treatment 925056.0 191000.0 0.4 1144419.0 424000.0 0.96 0.9679 0.9254 1696898 ChemDiv3_003841 COC(=O)c1ccc2nc(C)cc(O)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O14 compound treatment 1093409.0 359000.0 0.76 1308126.0 588000.0 1.34 1.4835 0.9643 1458066 ChemDiv3_003842 CCN(CC)C(=O)Oc1ccnc2cc(Cl)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O15 compound treatment 1089191.0 355000.0 0.75 1343689.0 624000.0 1.42 1.5343 0.956 1562065 ChemDiv3_003843 CCOC(=O)C1=C(Nc2nnnn2C1c3ccc(Br)cc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O16 compound treatment 1342724.0 608000.0 1.29 1262862.0 543000.0 1.23 1.7844 0.9998 3023750 ChemDiv3_003844 CNC(=O)CN1C(=O)C2C3CC(C=C3)C2C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O17 compound treatment 1165165.0 431000.0 0.91 1195543.0 475000.0 1.08 1.4101 0.9965 3118950 ChemDiv3_003845 COC(=O)C(CC(C)C)NC(=O)c1cc(nc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O18 compound treatment 1150556.0 416000.0 0.88 1167363.0 447000.0 1.02 1.3428 0.9975 1303884 ChemDiv3_003846 Nc1ncn(n1)C(=O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O19 compound treatment 1406340.0 672000.0 1.42 1132186.0 412000.0 0.94 1.6697 0.9794 3118951 ChemDiv3_003847 OC1(C2CCCCC2=NN1C(=O)c3ccccc3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O20 compound treatment 1235748.0 501000.0 1.06 1115218.0 395000.0 0.9 1.3867 0.9965 1381604 ChemDiv3_003848 Cc1cc(N2CCCC2)n3c4ccccc4nc3c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O21 compound treatment 1371160.0 637000.0 1.35 998076.0 278000.0 0.63 1.4014 0.9403 3118952 ChemDiv3_003849 OC1(CC(=NN1C(=O)C2CC2)c3ccc(Cl)cc3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O22 compound treatment 1130022.0 396000.0 0.84 949383.0 229000.0 0.52 0.9616 0.9739 1172393 ChemDiv3_003850 COc1ccc(CN2CCN(CC2)c3ncnc4scc(c5ccc(Cl)cc5)c34)cc1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O23 mock treatment 998562.0 264000.0 0.56 944724.0 225000.0 0.51 0.7571 0.999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 O24 mock treatment 467190.0 -267000.0 -0.57 457838.0 -262000.0 -0.6 -0.8222 -0.9997 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P01 compound treatment 345103.0 -389000.0 -0.83 377447.0 -343000.0 -0.78 -1.1345 -0.9996 1604660 ChemDiv3_003851 CCC(Sc1nnnn1c2ccccc2)C(=O)N3c4ccccc4Sc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P02 compound treatment 476328.0 -258000.0 -0.55 514843.0 -205000.0 -0.47 -0.7169 -0.9968 3118953 ChemDiv3_003852 FC(F)(F)c1cccc(/N=C/2\NC(=N)c3ccccc23)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P03 compound treatment 515188.0 -219000.0 -0.46 463938.0 -256000.0 -0.58 -0.7404 -0.9938 1143801 ChemDiv3_003853 OC1(CC(=O)c2ccc(Br)cc2)C(=O)N(Cc3ccccc3)c4ccccc41 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P04 compound treatment 721705.0 -12800.0 -0.03 648259.0 -71800.0 -0.16 -0.1345 -0.8133 1397253 ChemDiv3_003854 COc1ccc(cc1)C(=O)NCc2ccc3OCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P05 compound treatment 269943.0 -465000.0 -0.98 202105.0 -518000.0 -1.18 -1.529 -0.9961 3118954 ChemDiv3_003855 CCOC(=O)N1CCN(CC1)C(=O)CN(Cc2cccc(C)c2)S(=O)(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P06 compound treatment 621878.0 -113000.0 -0.24 595507.0 -125000.0 -0.28 -0.369 -0.9964 1737242 ChemDiv3_003856 CC1(C)Cc2nc3sc4c(NN)ncnc4c3cc2CO1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P07 compound treatment 665610.0 -68900.0 -0.15 763377.0 43300.0 0.1 -0.0336 -0.1906 3118955 ChemDiv3_003857 CS(=O)(=O)N(Cc1ccccc1)c2ccc(cc2)C(=O)NCCSc3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P08 compound treatment 729584.0 -4890.0 -0.01 818735.0 98700.0 0.22 0.1513 0.6737 1681828 ChemDiv3_003858 CCOc1ccc(cc1)N2CCc3c2nc4ccc(Br)cc4c3N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P09 compound treatment 690642.0 -43800.0 -0.09 598090.0 -122000.0 -0.28 -0.2618 -0.8952 3023751 ChemDiv3_003859 Cc1cc(C=C2C(=O)OC(C)(C)OC2=O)c(C)n1c3ccc(I)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P10 compound treatment 124187.0 -610000.0 -1.29 159836.0 -560000.0 -1.27 -1.8155 -1.0 3023752 ChemDiv3_003860 Clc1ccc(cc1)c2nc3cccc4cccc([nH]2)c43 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P11 compound treatment 517478.0 -217000.0 -0.46 672831.0 -47200.0 -0.11 -0.4012 -0.8493 1334154 ChemDiv3_003861 Clc1ccc(Cn2cc(C(=S)N3CCCC3)c4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P12 compound treatment 611260.0 -123000.0 -0.26 655246.0 -64800.0 -0.15 -0.2889 -0.9633 1027643 ChemDiv3_003862 OC(=O)CSC(=S)N1CCOCC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P13 compound treatment 936024.0 202000.0 0.43 937932.0 218000.0 0.5 0.6524 0.9973 3118956 ChemDiv3_003863 O=C1CC(CC(=O)C1=CNCCN2CCNCC2)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P14 compound treatment 1013279.0 279000.0 0.59 1059069.0 339000.0 0.77 0.963 0.9914 1538427 ChemDiv3_003864 CC1(C)Cc2nc3sc4c(NCC5CCCO5)ncnc4c3cc2CO1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P15 compound treatment 1181510.0 447000.0 0.95 1055450.0 335000.0 0.76 1.2093 0.9942 1219327 ChemDiv3_003865 O=C(Nc1ccccc1)c2cc3C(=O)CCCc3n(c4ccccc4)c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P16 compound treatment 1157166.0 423000.0 0.9 1028753.0 309000.0 0.7 1.1299 0.9927 1621677 ChemDiv3_003866 Cc1ccc(OCCN2CCN(CC2)c3ncnc4scc(c5ccccc5)c34)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P17 compound treatment 1191169.0 457000.0 0.97 1033073.0 313000.0 0.71 1.1878 0.9885 3118957 ChemDiv3_003867 O=C1NC(=O)/C(=C/c2c[nH]c3ccccc23)/C(=O)N1C4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P18 compound treatment 982729.0 248000.0 0.53 829008.0 109000.0 0.25 0.5473 0.9409 3023753 ChemDiv3_003868 CCc1nnc(NC(=O)C(C)N2C(=O)C3C4CC(C=C4)C3C2=O)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P19 compound treatment 832636.0 98200.0 0.21 809717.0 89700.0 0.2 0.2913 0.9999 3118958 ChemDiv3_003869 CCC(C)OC(=O)CSc1ncnc2sc3CC(C)CCc3c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P20 compound treatment 743637.0 9160.0 0.02 704068.0 -16000.0 -0.04 -0.0119 -0.2901 3023754 ChemDiv3_003870 Cc1cc2NC(=CC(=Nc2cc1C)c3cccs3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P21 compound treatment 662550.0 -71900.0 -0.15 653116.0 -66900.0 -0.15 -0.2154 -1.0 1262711 ChemDiv3_003871 CCC(C)OC(=O)C(C)Oc1ccc2c3CCCc3c(=O)oc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P22 compound treatment 573224.0 -161000.0 -0.34 640747.0 -79300.0 -0.18 -0.3692 -0.9553 1606981 ChemDiv3_003872 OC1(CC(=O)c2ccccc2)C(=O)N(CC=C)c3ccccc31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P23 mock treatment 548887.0 -186000.0 -0.39 583274.0 -137000.0 -0.31 -0.4981 -0.9932 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2011 P24 mock treatment 466097.0 -268000.0 -0.57 513148.0 -207000.0 -0.47 -0.7349 -0.9955 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A01 compound treatment 987726.0 279000.0 0.59 1060964.0 380000.0 0.86 1.029 0.9828 3118959 ChemDiv3_003873 COC(=O)C(CC(C)C)N1C=C(C(C(=C1)C(=O)OC)c2ccc(Br)cc2)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A02 compound treatment 279222.0 -430000.0 -0.91 278075.0 -403000.0 -0.92 -1.2916 -1.0 3023755 ChemDiv3_003874 CN(C)c1ccc(cc1)n2cccc2C=C3C(=O)N(C)C(=S)N(C)C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A03 compound treatment 510336.0 -199000.0 -0.42 595563.0 -85300.0 -0.19 -0.4348 -0.9381 1344150 ChemDiv3_003875 CSc1nnc-2c(OC(C)Nc3ccccc32)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A04 compound treatment 437954.0 -271000.0 -0.57 740591.0 59700.0 0.14 -0.3101 -0.5255 3118960 ChemDiv3_003876 O=C(CSc1nnc(COc2ccccc2)o1)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A05 compound treatment 506260.0 -203000.0 -0.43 623851.0 -57000.0 -0.13 -0.3954 -0.8812 3023867 ChemDiv3_003877 CCc1ccc2NC(=O)/C(=C/3\SC(=N)NC3=O)/c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A06 compound treatment 109256.0 -600000.0 -1.27 146962.0 -534000.0 -1.21 -1.7572 -0.9997 1867181 ChemDiv3_003878 CCOC(=O)c1c(C)n(Cc2ccccc2)c3ccc(OCC(O)CNC(C)(C)C)cc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A07 compound treatment 147674.0 -561000.0 -1.19 137682.0 -543000.0 -1.23 -1.7145 -0.9998 3118961 ChemDiv3_003879 CCc1ccc(/C=N/n2c(C)nnc2n3nc(C)cc3C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A08 compound treatment 735306.0 26400.0 0.06 765423.0 84600.0 0.19 0.1755 0.8766 1292139 ChemDiv3_003880 O=C(N1c2ccccc2Sc3ccccc13)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A09 compound treatment 972941.0 264000.0 0.56 926159.0 245000.0 0.56 0.7902 1.0 3119097 ChemDiv3_003881 CN1C(=O)/C(=C/2\S\C(=N/c3ccc(F)cc3)\NC2=O)/c4cc(Br)cc(C)c14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A10 compound treatment 878495.0 170000.0 0.36 762076.0 81200.0 0.18 0.3848 0.952 3023868 ChemDiv3_003882 CCCn1c(C)cc(C)c(C#N)c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A11 compound treatment 595332.0 -114000.0 -0.24 612340.0 -68500.0 -0.16 -0.2804 -0.9778 3023869 ChemDiv3_003883 CC(Cc1ccccc1)[n+]2[cH-]/c(=N\C(=O)N)/on2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A12 compound treatment 460715.0 -248000.0 -0.53 424619.0 -256000.0 -0.58 -0.784 -0.9987 1249817 ChemDiv3_003884 COc1cccc(CN2CCN(CC2)C(=O)c3cccs3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A13 compound treatment 252797.0 -456000.0 -0.97 249071.0 -432000.0 -0.98 -1.3779 -1.0 3119098 ChemDiv3_003885 Cc1ccc(Nc2nnc(c3ccc(C)c(c3)S(=O)(=O)NCC4CCCO4)c5ccccc25)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A14 compound treatment 344727.0 -364000.0 -0.77 379230.0 -302000.0 -0.69 -1.0308 -0.9983 3023870 ChemDiv3_003886 C(Cc1c[nH]c2ccccc12)NCc3cccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A15 compound treatment 712824.0 3930.0 0.01 840912.0 160000.0 0.36 0.2632 0.7231 1549146 ChemDiv3_003887 Clc1ccc(SCC(=O)Nc2ccc(cc2)c3nc4ncccc4o3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A16 compound treatment 456365.0 -253000.0 -0.54 794017.0 113000.0 0.26 -0.1967 -0.3311 3023871 ChemDiv3_003888 CCCN(CCC)C1=C(N(CC(=O)N)S(=O)(=O)c2ccccc12)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A17 compound treatment 593214.0 -116000.0 -0.25 611144.0 -69700.0 -0.16 -0.2855 -0.9777 1118860 ChemDiv3_003889 CCN(CC)CCC(=O)N1N=C(CC1c2ccc(OC)cc2)c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A18 compound treatment 453185.0 -256000.0 -0.54 673980.0 -6890.0 -0.02 -0.3944 -0.7272 1173412 ChemDiv3_003890 Cc1cc(C)cc(Oc2coc3cc(OCC(=O)NCc4ccccc4)ccc3c2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A19 compound treatment 767569.0 58700.0 0.12 529601.0 -151000.0 -0.34 -0.1552 -0.4245 1387978 ChemDiv3_003891 CN(C)C1CS(=O)(=O)CC1N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A20 compound treatment 634907.0 -74000.0 -0.16 568753.0 -112000.0 -0.25 -0.2912 -0.9728 1867723 ChemDiv3_003892 COc1ccccc1COc2ccc3c4CCCCCc4c(=O)oc3c2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A21 compound treatment 655685.0 -53200.0 -0.11 515791.0 -165000.0 -0.38 -0.3452 -0.8807 1361724 ChemDiv3_003893 O=C(NCc1ccccc1)NC2CCS(=O)(=O)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A22 compound treatment 580232.0 -129000.0 -0.27 551679.0 -129000.0 -0.29 -0.4006 -0.9993 1233165 ChemDiv3_003894 Cc1oc(cc1COc2ccc3c(C)c(Cc4ccccc4)c(=O)oc3c2C)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A23 mock treatment 493380.0 -216000.0 -0.46 440124.0 -241000.0 -0.55 -0.7101 -0.996 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 A24 mock treatment 380718.0 -328000.0 -0.7 407508.0 -273000.0 -0.62 -0.9314 -0.9984 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B01 compound treatment 465695.0 -243000.0 -0.52 466753.0 -214000.0 -0.49 -0.7088 -0.9996 3119099 ChemDiv3_003895 CN(/N=C/c1ccccc1)C2=NS(=O)(=O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B02 compound treatment 189259.0 -520000.0 -1.1 148350.0 -533000.0 -1.21 -1.6351 -0.9989 3119100 ChemDiv3_003896 COC(=O)C1=C(C)N/C(=C/c2cc(C)n(c2C)c3ccc(OC)c(Cl)c3)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B03 compound treatment 988651.0 280000.0 0.59 1002564.0 322000.0 0.73 0.9365 0.9946 3023872 ChemDiv3_003897 COc1cccc(C=C2C(=O)c3ccccc3C2=O)c1OC(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B04 compound treatment 1021580.0 313000.0 0.66 979222.0 298000.0 0.68 0.9484 0.9999 3023873 ChemDiv3_003898 Cc1ccc(cc1)c2c[n+]([O-])c3CCCc3[n+]2[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B05 compound treatment 623906.0 -85000.0 -0.18 704904.0 24000.0 0.05 -0.0888 -0.4714 3119101 ChemDiv3_003899 O=c1[nH]c2ccccc2n1CCCSc3nc4ccccc4[nH]3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B06 compound treatment 908804.0 200000.0 0.42 994253.0 313000.0 0.71 0.8035 0.9692 1401658 ChemDiv3_003900 CCOC(=O)c1c(oc2ccc(OCC(=O)OC)cc12)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B07 compound treatment 1051136.0 342000.0 0.73 1149204.0 468000.0 1.06 1.2659 0.9825 1210771 ChemDiv3_003901 CC(C)Cn1c(=O)c2cc3c(=O)n(CC(C)C)c(=O)c3c(C(=O)c4ccc(Cl)cc4)c2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B08 compound treatment 960195.0 251000.0 0.53 1188274.0 507000.0 1.15 1.1924 0.9384 1511593 ChemDiv3_003902 CC1CCN(CC1)S(=O)(=O)c2ccc(NC(=O)c3ccc(cc3)C(C)(C)C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B09 compound treatment 1049197.0 340000.0 0.72 1065527.0 385000.0 0.87 1.1285 0.9954 1487762 ChemDiv3_003903 O=S(=O)(NCCC1(CC2CC3CC(C2)C1)C3)c4cccc5nsnc45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B10 compound treatment 875089.0 166000.0 0.35 840360.0 159000.0 0.36 0.5055 0.9999 3023874 ChemDiv3_003904 COc1cc(/C=C\2/C(=N)N3C=CSC3=NC2=O)cc(OC)c1OCCOc4ccc(C)c(C)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B11 compound treatment 916097.0 207000.0 0.44 1075057.0 394000.0 0.9 0.9443 0.9461 3119102 ChemDiv3_003905 CN(C)/C=N/c1c(C#N)cnn1c2ncnc3sc4CCCc4c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B12 compound treatment 1012090.0 303000.0 0.64 1020279.0 339000.0 0.77 1.0001 0.9959 3023875 ChemDiv3_003906 COc1ccc2N3C(=NC(=O)C(Cc4ccccc4)C3=O)Sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B13 compound treatment 1248314.0 539000.0 1.14 989247.0 308000.0 0.7 1.3044 0.9724 1072961 ChemDiv3_003907 O=c1n(Cc2ccccc2)nc(c3ccccc3)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B14 compound treatment 985098.0 276000.0 0.59 1094215.0 413000.0 0.94 1.0785 0.9741 1739914 ChemDiv3_003908 Clc1ccc(cc1)S(=O)(=O)Nc2nc3ccccc3nc2NCCc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B15 compound treatment 762075.0 53200.0 0.11 1029509.0 349000.0 0.79 0.6402 0.7996 3023876 ChemDiv3_003909 C(Sc1nc2ccccc2[nH]1)/C=C/c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B16 compound treatment 562381.0 -147000.0 -0.31 566678.0 -114000.0 -0.26 -0.4032 -0.996 1325550 ChemDiv3_003910 NC1=C(C#N)C(c2sc3ccccc3c2O1)c4ccccc4OC(=O)c5ccccc5Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B17 compound treatment 803092.0 94200.0 0.2 1166364.0 485000.0 1.1 0.9217 0.8217 3023877 ChemDiv3_003911 CC(C)OC(=O)C1=c2s/c(=C\c3cccnc3)/c(=O)n2C(=C(C#N)C1c4cccnc4)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B18 compound treatment 946960.0 238000.0 0.5 1247126.0 566000.0 1.29 1.2672 0.9164 3119103 ChemDiv3_003912 COc1ccc(CN2C(=O)CC(Cc3ccc(C)cc3)C2=O)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B19 compound treatment 864231.0 155000.0 0.33 971476.0 291000.0 0.66 0.7 0.9483 1408601 ChemDiv3_003913 COc1ccc(CCNc2ncnc3sc4CCCCc4c23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B20 compound treatment 851602.0 143000.0 0.3 870824.0 190000.0 0.43 0.5193 0.9848 3023878 ChemDiv3_003914 N=C1NC(=O)/C(=C\c2cc3ccccc3nc2N4CCCCC4)/S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B21 compound treatment 910641.0 202000.0 0.43 942150.0 261000.0 0.59 0.7225 0.987 1543973 ChemDiv3_003915 COc1ccc2CNCCc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B22 compound treatment 805337.0 96400.0 0.2 895365.0 214000.0 0.49 0.4894 0.9255 3119104 ChemDiv3_003916 CC1CCN(CN2CC(COc3ccccc3C)OC2=O)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B23 mock treatment 700210.0 -8690.0 -0.02 885967.0 205000.0 0.47 0.3167 0.6787 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 B24 mock treatment 508001.0 -201000.0 -0.43 764508.0 83600.0 0.19 -0.1667 -0.3574 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C01 compound treatment 503556.0 -205000.0 -0.44 581552.0 -99300.0 -0.23 -0.4675 -0.9533 3119105 ChemDiv3_003917 COC(=O)C1=CN(C=C(C1c2ccsc2)C(=O)OC)c3cccc(c3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C02 compound treatment 785489.0 76600.0 0.16 895699.0 215000.0 0.49 0.4602 0.8941 3023910 ChemDiv3_003918 Cn1c(=O)n(C)c2cc(/C=C/3\C(=O)NC(=S)N(CC=C)C3=O)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C03 compound treatment 839257.0 130000.0 0.28 1063047.0 382000.0 0.87 0.8098 0.8882 3119106 ChemDiv3_003919 CSC1=N/C(=C\c2ccccc2C)/C(=O)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C04 compound treatment 917044.0 208000.0 0.44 1071274.0 390000.0 0.89 0.9397 0.948 3119107 ChemDiv3_003920 COc1ccc(CCCc2nnc(SCC(=O)Nc3cc(F)ccc3C)o2)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C05 compound treatment 986028.0 277000.0 0.59 1016018.0 335000.0 0.76 0.9542 0.9917 3023911 ChemDiv3_003921 C=CCN1C(=O)/C(=C/2\S/C(=N\c3ccccc3)/N(C2=O)c4ccccc4)/c5ccccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C06 compound treatment 1157178.0 448000.0 0.95 1070976.0 390000.0 0.89 1.2991 0.9994 1871099 ChemDiv3_003922 Cc1cccc(c1)N2C(=O)CC(Sc3nccc(C)n3)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C07 compound treatment 1049661.0 341000.0 0.72 1212984.0 532000.0 1.21 1.3663 0.9696 3023912 ChemDiv3_003923 CSC1=N/C(=C\C=C\c2cccs2)/C(=O)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C08 compound treatment 971186.0 262000.0 0.56 929168.0 248000.0 0.56 0.7924 1.0 1871152 ChemDiv3_003924 O=C(Cc1cccs1)N2c3ccccc3Sc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C09 compound treatment 1091227.0 382000.0 0.81 1242395.0 562000.0 1.28 1.4759 0.976 3023913 ChemDiv3_003925 CCSC1=N/C(=C\c2ccc(C)s2)/C(=O)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C10 compound treatment 1055103.0 346000.0 0.73 1154262.0 473000.0 1.08 1.28 0.9826 3119108 ChemDiv3_003926 CCCN1C(=O)/C(=C/c2ccc(o2)c3ccc(Cl)cc3)/C(=C(C#N)C1=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C11 compound treatment 1034341.0 325000.0 0.69 885556.0 205000.0 0.47 0.8169 0.9816 3023914 ChemDiv3_003927 N=c1[cH-][n+](CCc2ccccc2)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C12 compound treatment 614415.0 -94500.0 -0.2 643303.0 -37600.0 -0.09 -0.202 -0.9278 1216628 ChemDiv3_003928 CCOc1cc(CN2CCN(CC2)C(=O)COc3ccc(C)cc3)ccc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C13 compound treatment 1057315.0 348000.0 0.74 1135083.0 454000.0 1.03 1.2525 0.9865 3023915 ChemDiv3_003929 COc1ccc(cc1)c2nnc(Nc3cccc(c3)C(F)(F)F)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C14 compound treatment 1221467.0 513000.0 1.09 1310478.0 630000.0 1.43 1.7805 0.9908 3119109 ChemDiv3_003930 COc1cccc(CNCCc2c[nH]c3ccccc23)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C15 compound treatment 94075.0 -615000.0 -1.3 110807.0 -570000.0 -1.3 -1.8381 -1.0 1485768 ChemDiv3_003931 CCC(=O)NC(c1ccco1)c2cc(Cl)c3cccnc3c2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C16 compound treatment 1088971.0 380000.0 0.81 1103609.0 423000.0 0.96 1.2494 0.9962 1522564 ChemDiv3_003932 Cc1nc(NCCN2CCOCC2)c3sc4nc5CC(C)(C)OCc5cc4c3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C17 compound treatment 913283.0 204000.0 0.43 1124939.0 444000.0 1.01 1.0203 0.9287 3119239 ChemDiv3_003933 COc1ccc(cc1)C2CC(=NN2C(=O)CCN3CCOCC3)c4ccc(Br)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C18 compound treatment 840224.0 131000.0 0.28 863081.0 182000.0 0.41 0.4898 0.9813 1139781 ChemDiv3_003934 CC(C)COC(=O)c1ccc2NC(C3CC=CC3c2c1)c4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C19 compound treatment 1307649.0 599000.0 1.27 1202481.0 522000.0 1.19 1.7361 0.9994 1505314 ChemDiv3_003935 O=S1(=O)CCC(C1)N2C(=S)SC3CS(=O)(=O)C=C32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C20 compound treatment 1152351.0 443000.0 0.94 1164385.0 484000.0 1.1 1.4421 0.997 1867708 ChemDiv3_003936 COc1cc(COc2ccc3c4CCCc4c(=O)oc3c2)cc(OC)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C21 compound treatment 1114288.0 405000.0 0.86 1107040.0 426000.0 0.97 1.2928 0.9982 1172275 ChemDiv3_003937 CC1(CCS(=O)(=O)C1)NC(=S)Nc2ccc(O)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C22 compound treatment 1071278.0 362000.0 0.77 1062505.0 382000.0 0.87 1.1568 0.9982 1132860 ChemDiv3_003938 CN(C)C(=O)COc1cc2oc(=O)c3CCCc3c2cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C23 mock treatment 933958.0 225000.0 0.48 890119.0 209000.0 0.48 0.6738 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 C24 mock treatment 628710.0 -80200.0 -0.17 531183.0 -150000.0 -0.34 -0.3608 -0.9486 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D01 compound treatment 327901.0 -381000.0 -0.81 302379.0 -378000.0 -0.86 -1.1796 -0.9995 3023916 ChemDiv3_003939 O=S1(=O)N=C(N(CCC#N)/N=C/c2ccccc2)c3ccccc31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D02 compound treatment 602565.0 -106000.0 -0.23 823813.0 143000.0 0.32 0.0704 0.178 3119240 ChemDiv3_003940 COC(=O)C/1=C(C)NC(=O)\C1=C\c2ccc(CNS(=O)(=O)c3ccc(Cl)cc3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D03 compound treatment 656941.0 -52000.0 -0.11 748805.0 67900.0 0.15 0.0313 0.1652 3023917 ChemDiv3_003941 CCC(C)N1C(=O)S/C(=C/c2ccc3n(C)c(=O)n(C)c3c2)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D04 compound treatment 888869.0 180000.0 0.38 912097.0 231000.0 0.53 0.6415 0.9876 3119241 ChemDiv3_003942 [O-][n+]1cc(c2ccc(F)cc2)[n+]([O-])c3CCCc31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D05 compound treatment 863476.0 155000.0 0.33 833294.0 152000.0 0.35 0.4768 0.9996 3119242 ChemDiv3_003943 CCC(Sc1nnnn1c2ccccc2)C(=O)Nc3sc4CCCCc4c3C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D06 compound treatment 984501.0 276000.0 0.58 981230.0 300000.0 0.68 0.896 0.997 3023918 ChemDiv3_003944 CCCCc1c(O)nc(SCC(=O)N2CCCCC2)[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D07 compound treatment 817296.0 108000.0 0.23 1087206.0 406000.0 0.92 0.8157 0.8569 3119243 ChemDiv3_003945 COc1ccccc1CC(=O)Nc2ccc(cc2)c3nc4ccccc4[nH]3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D08 compound treatment 105133.0 -604000.0 -1.28 123240.0 -558000.0 -1.27 -1.8015 -1.0 3023919 ChemDiv3_003946 OC(Cn1c2ccccc2c3ccccc13)C[n+]4cccc5cccc(O)c45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D09 compound treatment 841240.0 132000.0 0.28 1058127.0 377000.0 0.86 0.8049 0.8919 3119244 ChemDiv3_003947 Nc1nc(SCC(=O)NCc2ccco2)c(C#N)cc1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D10 compound treatment 886854.0 178000.0 0.38 735061.0 54200.0 0.12 0.3539 0.8917 3119245 ChemDiv3_003948 COc1ccccc1N(C(=O)NCc2ccccc2)C3=NCC(C)S3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D11 compound treatment 839867.0 131000.0 0.28 996582.0 316000.0 0.72 0.7039 0.9146 1494926 ChemDiv3_003949 Cc1ccc(cc1)c2nnc(n3cnc4cc(C)c(C)cc34)c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D12 compound treatment 991536.0 283000.0 0.6 1055620.0 375000.0 0.85 1.0262 0.9852 1647264 ChemDiv3_003950 CCc1nc2oc(C(=O)c3ccccc3)c(N)c2c4CC(C)(C)OCc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D13 compound treatment 993471.0 285000.0 0.6 1051097.0 370000.0 0.84 1.0218 0.9867 1516394 ChemDiv3_003951 Cc1nc(Oc2ccc(NC(=O)c3ccccc3)cc2)c4c5CCCc5sc4n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D14 compound treatment 1105455.0 397000.0 0.84 1283510.0 603000.0 1.37 1.5633 0.9725 1736266 ChemDiv3_003952 CCc1ccc(Nc2nc3ccccc3nc2NS(=O)(=O)c4ccc(C)cc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D15 compound treatment 871602.0 163000.0 0.34 1147593.0 467000.0 1.06 0.9942 0.8911 1623664 ChemDiv3_003953 C(N1CCc2ccccc2C1)n3cnc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D16 compound treatment 1053723.0 345000.0 0.73 1149287.0 468000.0 1.06 1.27 0.9831 1684726 ChemDiv3_003954 COc1ccccc1NC(=O)COc2ccc3oc4CCCCc4c3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D17 compound treatment 950896.0 242000.0 0.51 1173840.0 493000.0 1.12 1.1553 0.9373 1574911 ChemDiv3_003955 NC1=C(C#N)C2(C(=O)N(CC=C)c3ccccc32)c4c(O1)c5ccccc5oc4=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D18 compound treatment 1098013.0 389000.0 0.82 1467348.0 786000.0 1.79 1.8477 0.9383 1249386 ChemDiv3_003956 O=C1CC(Cc2ccccc2)C(=O)N1c3nccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D19 compound treatment 1075378.0 366000.0 0.78 1225507.0 545000.0 1.24 1.425 0.9748 1153670 ChemDiv3_003957 Cc1sc2nc3c4ccccc4c(NCC5CCCO5)nn3c(=O)c2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D20 compound treatment 968879.0 260000.0 0.55 1241347.0 560000.0 1.27 1.2908 0.9297 3119246 ChemDiv3_003958 CC(=O)N1C(=N)S/C(=C/c2cc3ccccc3nc2Sc4ccccc4)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D21 compound treatment 790302.0 81400.0 0.17 1004219.0 323000.0 0.74 0.6419 0.85 1736305 ChemDiv3_003959 CC(C)COc1ccc2c3CCCCc3c(=O)oc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D22 compound treatment 660646.0 -48300.0 -0.1 862555.0 182000.0 0.41 0.2198 0.5164 3023957 ChemDiv3_003960 CC1CCN(CN2CC(Cn3c4ccccc4c5ccccc35)OC2=O)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D23 mock treatment 685898.0 -23000.0 -0.05 748508.0 67600.0 0.15 0.0743 0.4603 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 D24 mock treatment 464725.0 -244000.0 -0.52 540660.0 -140000.0 -0.32 -0.5914 -0.9729 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E01 compound treatment 2056206.0 1350000.0 2.86 2431449.0 1750000.0 3.98 4.834 0.9868 3119247 ChemDiv3_003961 COC(=O)CN1C=C(C(C(=C1)C(=O)OC)c2ccc(O)cc2)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E02 compound treatment 886557.0 178000.0 0.38 830134.0 149000.0 0.34 0.5063 0.9986 3119248 ChemDiv3_003962 CCC(C)n1cc(/C=C/2\C(=O)NC(=S)N(CC=C)C2=O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E03 compound treatment 777705.0 68800.0 0.15 693676.0 12800.0 0.03 0.1237 0.8318 3023958 ChemDiv3_003963 O=C/1N=C(S\C1=C/c2cccs2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E04 compound treatment 957587.0 249000.0 0.53 817360.0 136000.0 0.31 0.5922 0.9681 3023959 ChemDiv3_003964 O=C(CSc1nnc(COc2ccccc2)o1)NCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E05 compound treatment 917200.0 208000.0 0.44 847163.0 166000.0 0.38 0.5796 0.997 3119249 ChemDiv3_003965 CN/1C(=N)NC(=O)\C1=C\c2cccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E06 compound treatment 1201324.0 492000.0 1.04 865929.0 185000.0 0.42 1.0357 0.9202 1871115 ChemDiv3_003966 CC(C)(CO)NC(=O)c1sc2ccccc2c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E07 compound treatment 1063843.0 355000.0 0.75 956651.0 276000.0 0.63 0.9754 0.9959 3023960 ChemDiv3_003967 C(Sc1nnc-2c(OC(Nc3ccccc32)/C=C/c4ccco4)n1)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E08 compound treatment 994244.0 285000.0 0.6 919853.0 239000.0 0.54 0.8119 0.9986 3119250 ChemDiv3_003968 Cc1ccc(SCc2cc(O)nc(SCC(=O)n3c4ccccc4c5ccccc35)n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E09 compound treatment 1165674.0 457000.0 0.97 928060.0 247000.0 0.56 1.0821 0.9665 3023961 ChemDiv3_003969 CCSC1=N/C(=C\c2cccc(F)c2)/C(=O)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E10 compound treatment 1106014.0 397000.0 0.84 863140.0 182000.0 0.41 0.8883 0.9467 1156555 ChemDiv3_003970 CC1CCN(CC1)C(=O)CNS(=O)(=O)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E11 compound treatment 1271795.0 563000.0 1.19 847127.0 166000.0 0.38 1.1111 0.8876 1664682 ChemDiv3_003971 Cc1n[nH]c(C)c1N2C(=O)c3cccc4c(N)ccc(C2=O)c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E12 compound treatment 1776258.0 1070000.0 2.26 971645.0 291000.0 0.66 2.0675 0.877 1473240 ChemDiv3_003972 O=C(N1CCN(Cc2cccnc2)CC1)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E13 compound treatment 339716.0 -369000.0 -0.78 352414.0 -328000.0 -0.75 -1.0815 -0.9997 3119251 ChemDiv3_003973 CNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3ccc4OCOc4c3)c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E14 compound treatment 1314906.0 606000.0 1.28 1150346.0 469000.0 1.07 1.6632 0.9958 1668191 ChemDiv3_003974 CCOc1ccc(CN(CCc2ccc3OCOc3c2)Cc4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E15 compound treatment 1233922.0 525000.0 1.11 1207148.0 526000.0 1.2 1.6331 0.9993 1243341 ChemDiv3_003975 COc1ccc2cc(C3CC(=NN3C(=O)c4ccco4)c5ccc(OC)c(OC)c5)c(Cl)nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E16 compound treatment 1260622.0 552000.0 1.17 1098550.0 418000.0 0.95 1.4985 0.9947 3023962 ChemDiv3_003976 Fc1ccc(Nc2nc3ccccc3nc2Nc4ccc(F)cc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E17 compound treatment 982515.0 274000.0 0.58 866000.0 185000.0 0.42 0.7078 0.9876 1173393 ChemDiv3_003977 CC(C)N(C(=O)Cn1c2ccccc2c3nc4ccccc4nc13)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E18 compound treatment 1405294.0 696000.0 1.48 1115545.0 435000.0 0.99 1.7427 0.9809 3023963 ChemDiv3_003978 OC(C#CCN1CCOCC1)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E19 compound treatment 1347730.0 639000.0 1.35 1098711.0 418000.0 0.95 1.6294 0.985 3119252 ChemDiv3_003979 CCN(CC)C(=S)SC1=CCS(=O)(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E20 compound treatment 1293369.0 584000.0 1.24 1278354.0 597000.0 1.36 1.8367 0.9989 1158512 ChemDiv3_003980 COc1ccc2c(c1)c(=O)oc3cc(OC(C)C)ccc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E21 compound treatment 1069351.0 360000.0 0.76 1056163.0 375000.0 0.85 1.1437 0.9985 3119253 ChemDiv3_003981 CC12CS(=O)(=O)CC2SC(=S)N1Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E22 compound treatment 866774.0 158000.0 0.33 1048149.0 367000.0 0.84 0.8271 0.9194 1357925 ChemDiv3_003982 CN(C)C(=O)COc1cc(C)cc2oc(=O)c3CCCCc3c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E23 mock treatment 862014.0 153000.0 0.32 673922.0 -6950.0 -0.02 0.2184 0.6719 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 E24 mock treatment 714771.0 5870.0 0.01 535259.0 -146000.0 -0.33 -0.2253 -0.68 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F01 compound treatment 567412.0 -141000.0 -0.3 795058.0 114000.0 0.26 -0.0285 -0.0719 3023964 ChemDiv3_003983 CN1C(=O)/C(=C/c2ccc(o2)c3ccc(Cl)cc3)/C(=C(C#N)C1=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F02 compound treatment 846746.0 138000.0 0.29 909060.0 228000.0 0.52 0.5735 0.9631 3119382 ChemDiv3_003984 O=C(NC1=NCCS1)c2cc3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F03 compound treatment 184429.0 -524000.0 -1.11 147768.0 -533000.0 -1.21 -1.6432 -0.9991 1627858 ChemDiv3_003985 CN(C)c1ccc2nc3C(=O)c4ccccc4C(=O)c3nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F04 compound treatment 1012617.0 304000.0 0.64 852881.0 172000.0 0.39 0.7318 0.9714 3119383 ChemDiv3_003986 CC1=[N+]([O-])C(C)(C)[N+](=C1c2ccc(C)cc2)[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F05 compound treatment 1046189.0 337000.0 0.72 854685.0 174000.0 0.4 0.785 0.9609 3119384 ChemDiv3_003987 COC(=O)c1ccc(NC(=O)CC2Sc3ccc(cc3NC2=O)C(F)(F)F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F06 compound treatment 1134383.0 425000.0 0.9 1159425.0 479000.0 1.09 1.4072 0.9957 3023965 ChemDiv3_003988 CC(C)Cc1c(O)nc(SCC(=O)NC(C)(C)C)[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F07 compound treatment 850011.0 141000.0 0.3 884519.0 204000.0 0.46 0.5389 0.9777 3119385 ChemDiv3_003989 Cc1ccccc1OCC(=O)Nc2cccc(c2)c3nnc(o3)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F08 compound treatment 888971.0 180000.0 0.38 1057091.0 376000.0 0.86 0.8748 0.9339 3023966 ChemDiv3_003990 COC(=O)c1c(C)c(=O)[nH]c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F09 compound treatment 1078746.0 370000.0 0.78 1087640.0 407000.0 0.92 1.2084 0.9966 1509397 ChemDiv3_003991 Fc1ccc(cc1)C(=O)Nc2ncnc3sc4CCCCCc4c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F10 compound treatment 1048350.0 339000.0 0.72 910455.0 230000.0 0.52 0.8779 0.9876 3023967 ChemDiv3_003992 FC(F)(F)C1(N=C(OC(=N1)c2ccccc2)N3CCCCC3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F11 compound treatment 1375610.0 667000.0 1.41 1573883.0 893000.0 2.03 2.4351 0.9843 1229183 ChemDiv3_003993 Cc1sc2nc3c4ccccc4c(NCCO)nn3c(=O)c2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F12 compound treatment 1693738.0 985000.0 2.09 1815676.0 1130000.0 2.58 3.3007 0.9945 1299234 ChemDiv3_003994 COC(=O)c1c(N)n(CCc2ccccc2)c3nc4ccccc4nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F13 compound treatment 1335582.0 627000.0 1.33 1624321.0 943000.0 2.14 2.4562 0.9735 1319064 ChemDiv3_003995 Cc1ccc(Oc2nnc(c3cccs3)c4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F14 compound treatment 1489707.0 781000.0 1.66 1698045.0 1020000.0 2.31 2.8057 0.9866 3119386 ChemDiv3_003996 Cc1cccc(N/C=C\2/C(=O)N(C(=O)c3ccccc23)c4ccccc4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F15 compound treatment 1267814.0 559000.0 1.18 1440443.0 760000.0 1.73 2.059 0.9831 3023968 ChemDiv3_003997 Cn1nc(CC(=O)Nc2nc(cs2)c3ccccc3)c4ccccc4c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F16 compound treatment 1050739.0 342000.0 0.72 1213882.0 533000.0 1.21 1.3693 0.9698 3119387 ChemDiv3_003998 COc1ccc(/N=C/c2c(O)ccc3oc4CCCCc4c23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F17 compound treatment 976240.0 267000.0 0.57 1248418.0 568000.0 1.29 1.3132 0.9318 1229320 ChemDiv3_003999 CCOC(=O)CN1C(=O)C2(C(=C(N)OC3=C2C(=O)CC(C)(C)C3)C(=O)OCC)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F18 compound treatment 714584.0 5690.0 0.01 829154.0 148000.0 0.34 0.2469 0.7319 1796400 ChemDiv3_004000 COc1ccc(CCn2cnc3sc4CCCCc4c3c2=N)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F19 compound treatment 243987.0 -465000.0 -0.99 220506.0 -460000.0 -1.05 -1.437 -0.9995 1598055 ChemDiv3_004001 Cc1cc(C(=O)CSc2nnc3cc(C)c4ccccc4n23)c(C)n1Cc5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F20 compound treatment 974448.0 266000.0 0.56 1059271.0 378000.0 0.86 1.0064 0.9789 3024019 ChemDiv3_004002 CC(=O)N1C(=N)S/C(=C/c2cc3ccc(C)cc3nc2O)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F21 compound treatment 823746.0 115000.0 0.24 1099947.0 419000.0 0.95 0.8459 0.8602 1409929 ChemDiv3_004003 Cn1nc(C(=O)O)c2ccccc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F22 compound treatment 853927.0 145000.0 0.31 858197.0 177000.0 0.4 0.5025 0.9911 1387840 ChemDiv3_004004 CCOC(=O)Cc1c(C)nc(Cc2ccc(OC(C)C)cc2)nc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F23 mock treatment 921739.0 213000.0 0.45 591803.0 -89100.0 -0.2 0.1759 0.3556 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 F24 mock treatment 556665.0 -152000.0 -0.32 583108.0 -97800.0 -0.22 -0.3854 -0.9834 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G01 compound treatment 2269531.0 1560000.0 3.31 2525452.0 1840000.0 4.19 5.3049 0.9931 3119388 ChemDiv3_004005 COC(=O)C1=CN(C=C(C1c2ccccc2)C(=O)OC)C3CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G02 compound treatment 876288.0 167000.0 0.35 808662.0 128000.0 0.29 0.4564 0.9951 3024021 ChemDiv3_004006 Cc1cc(/C=C/2\C(=O)NC(=S)N(CC=C)C2=O)c(C)n1c3ccccn3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G03 compound treatment 986758.0 278000.0 0.59 1017210.0 336000.0 0.76 0.9572 0.9917 3119389 ChemDiv3_004007 c1ccc2sc(nc2c1)c3cccc(n3)c4nc5ccccc5s4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G04 compound treatment 1064452.0 356000.0 0.75 858993.0 178000.0 0.4 0.8194 0.9576 3119390 ChemDiv3_004008 COc1ccc(Cc2nnc(SCC(=O)Nc3ccc(OC)cc3)o2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G05 compound treatment 1079155.0 370000.0 0.78 977401.0 297000.0 0.67 1.0317 0.9971 3024022 ChemDiv3_004009 COc1ccc(/C=C/C=N/n2c(SC)nnc2c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G06 compound treatment 1260347.0 551000.0 1.17 1316193.0 635000.0 1.44 1.848 0.9945 1871125 ChemDiv3_004010 Cc1c(C)c2ccccc2n1C(=O)CSc3nc4ccccc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G07 compound treatment 1087319.0 378000.0 0.8 1286501.0 606000.0 1.38 1.5409 0.9669 1673764 ChemDiv3_004011 CC(=O)N1C(Oc2nc(SCC=C)nnc2-c3ccccc13)c4ccc(o4)c5ccc(F)cc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G08 compound treatment 1098889.0 390000.0 0.83 864247.0 183000.0 0.42 0.8794 0.9498 3119391 ChemDiv3_004012 COc1ccc(NC(=O)C2CC(=O)N=C(Nc3ccccc3)S2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G09 compound treatment 1304862.0 596000.0 1.26 1354099.0 673000.0 1.53 1.9757 0.9955 1613829 ChemDiv3_004013 CCSc1nnc(c(O)n1)c2ccccc2NC(=O)CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G10 compound treatment 1304561.0 596000.0 1.26 1187307.0 506000.0 1.15 1.7071 0.9989 1558726 ChemDiv3_004014 CC(C)(C)NC(=O)N1c2ccccc2Sc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G11 compound treatment 1470119.0 761000.0 1.61 1324735.0 644000.0 1.46 2.1762 0.9988 3119392 ChemDiv3_004015 Cc1nn(C)c(C)c1NC(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G12 compound treatment 1536254.0 827000.0 1.75 1582892.0 902000.0 2.05 2.6904 0.997 1465103 ChemDiv3_004016 CCc1ccc(CN2CCN(Cc3cccc(OC)c3)CC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G13 compound treatment 1521617.0 813000.0 1.72 1501630.0 821000.0 1.87 2.5378 0.9992 3119393 ChemDiv3_004017 CCNS(=O)(=O)c1cc(ccc1C)c2nnc(Nc3ccc(F)cc3)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G14 compound treatment 1305842.0 597000.0 1.27 1606546.0 926000.0 2.1 2.383 0.9704 1303056 ChemDiv3_004018 CC(C)(C)NC1=C(N(CC(=O)c2ccccc2)S(=O)(=O)c3ccccc13)C(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G15 compound treatment 1411545.0 703000.0 1.49 1512775.0 832000.0 1.89 2.3907 0.993 1692964 ChemDiv3_004019 CCC(=O)N1N=C(CC1c2cc3cc(OC)ccc3nc2Cl)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G16 compound treatment 1282527.0 574000.0 1.22 1607350.0 926000.0 2.11 2.3493 0.9659 1699942 ChemDiv3_004020 Brc1ccc(cc1)C2NC(=O)c3ccccc3O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G17 compound treatment 1369925.0 661000.0 1.4 1581231.0 900000.0 2.05 2.4384 0.9829 3024023 ChemDiv3_004021 CC(=O)OC1CCS(=O)(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G18 compound treatment 1216549.0 508000.0 1.08 1256410.0 576000.0 1.31 1.6863 0.9953 3119394 ChemDiv3_004022 CCCc1n[nH]c2OC(=C(C#N)C(CCc3ccccc3)c12)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G19 compound treatment 1359926.0 651000.0 1.38 1233967.0 553000.0 1.26 1.8651 0.9989 3024024 ChemDiv3_004023 CC1(CCS(=O)(=O)C1)NC(=S)NCC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G20 compound treatment 1296649.0 588000.0 1.25 1016108.0 335000.0 0.76 1.42 0.9722 1713974 ChemDiv3_004024 Oc1cc(OCC(=O)c2ccccc2)cc3oc(cc(=O)c13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G21 compound treatment 1089949.0 381000.0 0.81 801197.0 120000.0 0.27 0.7647 0.8966 1338699 ChemDiv3_004025 CCCCN(C1CCS(=O)(=O)C1)C(=O)Nc2cccc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G22 compound treatment 1890549.0 1180000.0 2.51 1846909.0 1170000.0 2.65 3.6459 0.9996 1306939 ChemDiv3_004026 Cc1c(OC(=O)c2ccco2)ccc3c4CCCc4c(=O)oc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G23 mock treatment 905429.0 197000.0 0.42 664826.0 -16000.0 -0.04 0.2688 0.6427 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 G24 mock treatment 548743.0 -160000.0 -0.34 639376.0 -41500.0 -0.09 -0.3068 -0.8706 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H01 compound treatment 551519.0 -157000.0 -0.33 719488.0 38600.0 0.09 -0.1738 -0.5039 3119395 ChemDiv3_004027 CC(C)N1C(=O)S/C(=C/c2ccc(Sc3nc4ccccc4[nH]3)o2)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H02 compound treatment 903961.0 195000.0 0.41 880374.0 200000.0 0.45 0.6131 0.9989 3024025 ChemDiv3_004028 Cc1c(c2ccco2)[n+]([O-])c(c(C)[n+]1[O-])c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H03 compound treatment 1062227.0 353000.0 0.75 937075.0 256000.0 0.58 0.9415 0.9923 3119396 ChemDiv3_004029 C/C(=N\O)/CCc1oc2ccccc2c1c3ccc(C)o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H04 compound treatment 1159127.0 450000.0 0.95 887649.0 207000.0 0.47 1.0073 0.9468 3024026 ChemDiv3_004030 CC1N(O)C(C)(C)[N+](=C1c2ccccc2)[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H05 compound treatment 1310234.0 601000.0 1.27 896456.0 216000.0 0.49 1.248 0.9138 3024027 ChemDiv3_004031 CC(=O)N/C(=C\c1cccs1)/C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H06 compound treatment 1311238.0 602000.0 1.28 992839.0 312000.0 0.71 1.4045 0.9615 3119397 ChemDiv3_004032 CCSc1nc(O)c(C(C)CC)c(=O)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H07 compound treatment 824107.0 115000.0 0.24 849012.0 168000.0 0.38 0.443 0.9766 1130593 ChemDiv3_004033 O=C(Cc1ccccc1)Nc2cccc(c2)S(=O)(=O)c3cccc(NC(=O)Cc4ccccc4)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H08 compound treatment 1143187.0 434000.0 0.92 1199435.0 519000.0 1.18 1.4847 0.9925 3024028 ChemDiv3_004034 CCOC(=O)c1nn(c(C#N)c1NC(=O)c2nn(CC)cc2Br)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H09 compound treatment 1282731.0 574000.0 1.22 1243884.0 563000.0 1.28 1.7653 0.9997 1423488 ChemDiv3_004035 COc1cc2c(cc1NP(=O)(C)Oc3ccccc3)oc4ccccc42 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H10 compound treatment 1387336.0 678000.0 1.44 1706842.0 1030000.0 2.33 2.6664 0.973 3024029 ChemDiv3_004036 COc1ccc(Cl)cc1NC2=NCC(C)S2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H11 compound treatment 1596377.0 887000.0 1.88 1718848.0 1040000.0 2.36 2.9991 0.9937 1247540 ChemDiv3_004037 CC1CCN(CC1)c2nn3c(=O)c4c(C)c(C)sc4nc3c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H12 compound treatment 1619520.0 911000.0 1.93 2063879.0 1380000.0 3.14 3.5884 0.9726 1685422 ChemDiv3_004038 CCOC(=O)c1c(N)n(C2CCCCC2)c3nc4ccccc4nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H13 compound treatment 1589595.0 881000.0 1.87 1909870.0 1230000.0 2.79 3.296 0.9808 1241398 ChemDiv3_004039 C1CCCN(CC1)c2nnc(c3cccs3)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H14 compound treatment 1888638.0 1180000.0 2.5 1877305.0 1200000.0 2.72 3.6919 0.9991 3119548 ChemDiv3_004040 CCc1ccc(N/C=C\2/C(=O)N(C(=O)c3ccccc23)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H15 compound treatment 1986962.0 1280000.0 2.71 1538611.0 858000.0 1.95 3.2948 0.987 3024030 ChemDiv3_004041 O=C(Oc1ccc(cc1)N(Cc2cccs2)C3=NS(=O)(=O)c4ccccc34)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H16 compound treatment 1807309.0 1100000.0 2.33 1537688.0 857000.0 1.95 3.024 0.9961 3119549 ChemDiv3_004042 Oc1ccc2oc3CCCCc3c2c1/C=N/N4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H17 compound treatment 1298793.0 590000.0 1.25 1319772.0 639000.0 1.45 1.9114 0.9972 1705908 ChemDiv3_004043 CCOC(=O)CN1C(=O)C2(C(=C(N)Oc3[nH]nc(C)c32)C#N)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H18 compound treatment 1582570.0 874000.0 1.85 1426481.0 746000.0 1.7 2.5083 0.999 3024031 ChemDiv3_004044 COc1ccc(CCn2cnc3oc(c(c4ccccc4)c3c2=N)c5ccccc5)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H19 compound treatment 1453156.0 744000.0 1.58 1107035.0 426000.0 0.97 1.8008 0.9726 3119550 ChemDiv3_004045 Cc1nc(SC2CCCCN(C(=O)c3ccc(Cl)cc3)C2=O)c4c5CCCCc5sc4n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H20 compound treatment 1271878.0 563000.0 1.19 1026367.0 345000.0 0.79 1.3994 0.9794 3442340 ChemDiv3_004046 CC(C)CC(Nc1ncnc2sc3CCCc3c12)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H21 compound treatment 1463909.0 755000.0 1.6 886281.0 205000.0 0.47 1.462 0.8769 3024084 ChemDiv3_004047 COC(=O)/C=c/1\sc2ncnn2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H22 compound treatment 1139209.0 430000.0 0.91 779308.0 98400.0 0.22 0.8033 0.8552 1470170 ChemDiv3_004048 Nc1cc(=O)nc(SCC(=O)NCc2ccccc2)n1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H23 mock treatment 1203274.0 494000.0 1.05 850277.0 169000.0 0.39 1.0134 0.9076 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 H24 mock treatment 588014.0 -121000.0 -0.26 658044.0 -22800.0 -0.05 -0.2179 -0.8334 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I01 compound treatment 390812.0 -318000.0 -0.67 335853.0 -345000.0 -0.78 -1.0315 -0.9972 3024085 ChemDiv3_004049 Cc1[n+](CC=C)n(C)c2cc(Cl)c(Cl)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I02 compound treatment 1102883.0 394000.0 0.84 1083148.0 402000.0 0.91 1.2373 0.999 3119551 ChemDiv3_004050 COCCn1c(C)cc(/C=C/2\C(=O)NC(=S)N(CC=C)C2=O)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I03 compound treatment 1097306.0 388000.0 0.82 1138984.0 458000.0 1.04 1.3187 0.9932 1185967 ChemDiv3_004051 CCSc1nnc-2c(OC(Nc3ccccc32)c4cc5OCOc5cc4Cl)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I04 compound treatment 913817.0 205000.0 0.43 1024904.0 344000.0 0.78 0.8603 0.9615 3119552 ChemDiv3_004052 COc1ccc(Cl)c(NC2=NC(=O)/C(=C\c3cccnc3)/S2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I05 compound treatment 1166700.0 458000.0 0.97 1225493.0 545000.0 1.24 1.5618 0.9927 1528287 ChemDiv3_004053 CSc1nnc-2c(OC(C)N(C(=O)C)c3ccccc32)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I06 compound treatment 1041784.0 333000.0 0.71 1200649.0 520000.0 1.18 1.3346 0.9696 1788578 ChemDiv3_004054 O=C(CSc1nnc(o1)c2ccccc2)N3c4ccccc4CCc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I07 compound treatment 1227057.0 518000.0 1.1 1424635.0 744000.0 1.69 1.9724 0.9782 3024086 ChemDiv3_004055 COC(=O)C1=C(C)NC(=S)NC1c2cc3OCOc3cc2Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I08 compound treatment 714725.0 5830.0 0.01 699002.0 18100.0 0.04 0.0379 0.8803 3119553 ChemDiv3_004056 FC(F)(F)c1cccc(c1)n2c(=O)oc3ccc(Cl)cc3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I09 compound treatment 1121901.0 413000.0 0.88 1280463.0 600000.0 1.36 1.583 0.9771 3119554 ChemDiv3_004057 CCc1ccc2NC(=O)/C(=C/3\S\C(=N/c4cccc(Cl)c4C)\NC3=O)/c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I10 compound treatment 1479727.0 771000.0 1.63 1559748.0 879000.0 2.0 2.5684 0.995 1437793 ChemDiv3_004058 O=C(NCCc1ccccc1)N2c3ccccc3Sc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I11 compound treatment 1762430.0 1050000.0 2.23 1808824.0 1130000.0 2.56 3.3926 0.9976 3119555 ChemDiv3_004059 COC(=O)c1cc2c(C)nn(c3ccccc3)c2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I12 compound treatment 1553536.0 845000.0 1.79 1635631.0 955000.0 2.17 2.8011 0.9954 1679546 ChemDiv3_004060 CCc1ccc(CN2CCN(Cc3ccc4OCOc4c3)CC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I13 compound treatment 1697360.0 988000.0 2.1 1735189.0 1050000.0 2.4 3.1767 0.9978 3119556 ChemDiv3_004061 CCNS(=O)(=O)c1cc(ccc1C)c2nnc(OC)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I14 compound treatment 2129575.0 1420000.0 3.01 1610290.0 929000.0 2.11 3.6238 0.985 3024087 ChemDiv3_004062 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I15 compound treatment 1330249.0 621000.0 1.32 1587602.0 907000.0 2.06 2.3891 0.9766 1737307 ChemDiv3_004063 O=C(N1N=C(CC1c2ccc3nccnc3c2)c4ccccc4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I16 compound treatment 1082352.0 373000.0 0.79 1333953.0 653000.0 1.48 1.6097 0.9566 3024088 ChemDiv3_004064 NC(=N)SCC1CN=C(S1)N2CCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I17 compound treatment 1440783.0 732000.0 1.55 1369219.0 688000.0 1.56 2.2037 1.0 1449842 ChemDiv3_004065 CNC(=S)NC1CCS(=O)(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I18 compound treatment 1239068.0 530000.0 1.12 1245858.0 565000.0 1.28 1.703 0.9978 3119557 ChemDiv3_004066 CCCOc1ccc(cc1OCC)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I19 compound treatment 1282041.0 573000.0 1.22 1275524.0 595000.0 1.35 1.8152 0.9986 3024089 ChemDiv3_004067 CCCC(NC1CCS(=O)(=O)C1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I20 compound treatment 1405935.0 697000.0 1.48 1470234.0 789000.0 1.79 2.3139 0.9953 1874878 ChemDiv3_004068 COc1ccc2c(c1)c(=O)oc3c(C)c(OC(C(=O)O)c4ccccc4)ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I21 compound treatment 1141294.0 432000.0 0.92 1057605.0 377000.0 0.86 1.2538 0.9994 1557945 ChemDiv3_004069 CCc1ccccc1NC(=O)CC2CS(=O)(=O)CC2CC(=O)Nc3ccccc3CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I22 compound treatment 633927.0 -75000.0 -0.16 611427.0 -69400.0 -0.16 -0.224 -1.0 3024090 ChemDiv3_004070 Cc1cc(OC(=O)c2cccs2)c3c4CCCc4c(=O)oc3c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I23 mock treatment 1049140.0 340000.0 0.72 1006510.0 326000.0 0.74 1.0336 0.9999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 I24 mock treatment 642638.0 -66300.0 -0.14 843991.0 163000.0 0.37 0.1629 0.4108 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J01 compound treatment 578144.0 -131000.0 -0.28 505535.0 -175000.0 -0.4 -0.4779 -0.9842 3024091 ChemDiv3_004071 CC(C)N1C(=O)S/C(=C/c2cc(C)n(c2C)c3ccncc3)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J02 compound treatment 1044855.0 336000.0 0.71 1015694.0 335000.0 0.76 1.0419 0.9994 3119558 ChemDiv3_004072 CC(=O)OC1CCC(OC(=O)C)c2c1[n+]([O-])c(C)c(C)[n+]2[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J03 compound treatment 566943.0 -142000.0 -0.3 658951.0 -21900.0 -0.05 -0.248 -0.8131 3024092 ChemDiv3_004073 S=c1cc(oc(c1)c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J04 compound treatment 1136263.0 427000.0 0.91 1164361.0 483000.0 1.1 1.4179 0.9954 3119559 ChemDiv3_004074 Cc1c(c2ccccc2)[n+]([O-])c(c(C)[n+]1[O-])c3ccc(Br)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J05 compound treatment 1462531.0 754000.0 1.6 1558789.0 878000.0 2.0 2.5411 0.9939 1128591 ChemDiv3_004075 COc1ccc(CC(=O)Nc2cccc(c2)c3nc4cc5ccccc5cc4[nH]3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J06 compound treatment 1106726.0 398000.0 0.84 1066721.0 386000.0 0.88 1.2167 0.9998 1255030 ChemDiv3_004076 COc1ccc(cc1OC)C2C(c3cc(OC)c(OC)cc3C2=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J07 compound treatment 1542712.0 834000.0 1.77 1487224.0 806000.0 1.83 2.5462 0.9998 3119560 ChemDiv3_004077 O=C(Nc1cccc(c1)c2nc3ccccc3c(=O)o2)C4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J08 compound treatment 1149878.0 441000.0 0.93 1300597.0 620000.0 1.41 1.6573 0.9801 3024093 ChemDiv3_004078 CCOC(=O)c1nn(c(C(=O)OCC)c1NC(=O)C2CCCCC2)c3ccc(OC)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J09 compound treatment 1596640.0 888000.0 1.88 1734764.0 1050000.0 2.4 3.025 0.9929 1215988 ChemDiv3_004079 OC(=O)c1c2CC(CCc2nc3ccccc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J10 compound treatment 1219132.0 510000.0 1.08 1499352.0 818000.0 1.86 2.0807 0.9667 3119561 ChemDiv3_004080 CC1CN=C(S1)N(C(=O)Nc2ccccc2)c3cccc(c3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J11 compound treatment 1847483.0 1140000.0 2.41 1900931.0 1220000.0 2.77 3.6682 0.9976 1549011 ChemDiv3_004081 Cc1ccc(cc1)c2nn3c(=O)c4ccccc4nc3c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J12 compound treatment 1016254.0 307000.0 0.65 1018840.0 338000.0 0.77 1.0041 0.9966 1317257 ChemDiv3_004082 CCc1ccc(cc1)n2c(N)c(C(=O)OC)c3nc4ccccc4nc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J13 compound treatment 1389669.0 681000.0 1.44 1907242.0 1230000.0 2.79 2.9921 0.953 3024094 ChemDiv3_004083 O=C(CSc1ncnc2sc(cc12)c3ccccc3)c4ccc5OCCOc5c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J14 compound treatment 2019888.0 1310000.0 2.78 1907236.0 1230000.0 2.79 3.9368 1.0 3119562 ChemDiv3_004084 FC(F)(F)c1cccc(N/C=C\2/C(=O)N(C(=O)c3ccccc23)c4ccccc4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J15 compound treatment 725941.0 17000.0 0.04 756069.0 75200.0 0.17 0.1464 0.838 1305983 ChemDiv3_004085 CCCN1CC=C2C(C1)C3(C(=O)Nc4ccccc43)C(C#N)(C#N)C(=C2C#N)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J16 compound treatment 1563220.0 854000.0 1.81 1808361.0 1130000.0 2.56 3.0933 0.9855 1458619 ChemDiv3_004086 CC(C)(C)c1nc2scc(c3ccccc3)c2c(=O)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J17 compound treatment 1278635.0 570000.0 1.21 1436112.0 755000.0 1.72 2.0682 0.9852 1274153 ChemDiv3_004087 CCOC(=O)C1=C(N)Oc2c(c(=O)oc3ccccc23)C41C(=O)N(CC(=O)OC)c5ccccc54 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J18 compound treatment 1360452.0 652000.0 1.38 1398430.0 718000.0 1.63 2.1303 0.9966 1393431 ChemDiv3_004088 CCn1c(=O)c2c(-c3ccccc3CC42CCCCC4)n5c(SCC(=O)N)nnc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J19 compound treatment 1252139.0 543000.0 1.15 1224892.0 544000.0 1.24 1.6889 0.9994 3119696 ChemDiv3_004089 CCN(CC)C(=O)O[n+]1cccc(CC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J20 compound treatment 1153753.0 445000.0 0.94 1346502.0 666000.0 1.51 1.737 0.9741 3119697 ChemDiv3_004090 C=CCN1C(=C(OC(=O)c2ccccc2)c3ccccc3S1(=O)=O)C(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J21 compound treatment 1375377.0 666000.0 1.41 1087610.0 407000.0 0.92 1.653 0.9789 1423420 ChemDiv3_004091 Cc1cc(C)n(n1)c2nnc(C)n2NC(=S)NCC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J22 compound treatment 934954.0 226000.0 0.48 926722.0 246000.0 0.56 0.7341 0.9971 3119698 ChemDiv3_004092 COC(=O)/C=C/1\N(C(=NC1=O)Nc2nc(C)cc(C)n2)c3cccc(C)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J23 mock treatment 1052650.0 344000.0 0.73 1035238.0 354000.0 0.81 1.085 0.9987 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 J24 mock treatment 9.0 -709000.0 -1.5 815898.0 135000.0 0.31 -0.8456 -0.5513 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K01 compound treatment 652169.0 -56700.0 -0.12 569203.0 -112000.0 -0.25 -0.2646 -0.9417 3023297 ChemDiv3_004093 Oc1cc(C2C(=O)c3ccccc3C2=O)c4ccc5ccccc5c4n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K02 compound treatment 1123863.0 415000.0 0.88 955357.0 274000.0 0.62 1.0633 0.9859 3119699 ChemDiv3_004094 COCCn1c(C)cc(C=C2C(=O)N(C)C(=S)N(C)C2=O)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K03 compound treatment 1132193.0 423000.0 0.9 1044955.0 364000.0 0.83 1.2199 0.9992 1169810 ChemDiv3_004095 CSc1nnc-2c(OC(Nc3ccccc32)c4ccccc4)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K04 compound treatment 1041331.0 332000.0 0.7 1136101.0 455000.0 1.03 1.2302 0.9825 3119700 ChemDiv3_004096 OC(=O)c1ccc(cc1)c2ccc(/C=C\3/SC(=NC3=O)Nc4cccc(c4)C(=O)O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K05 compound treatment 1117924.0 409000.0 0.87 1102213.0 421000.0 0.96 1.2905 0.9988 3119701 ChemDiv3_004097 CC/1=NN(C(=O)\C1=C/Nc2cc(C)ccn2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K06 compound treatment 1360729.0 652000.0 1.38 1183715.0 503000.0 1.14 1.7855 0.9956 1871177 ChemDiv3_004098 COc1ccc(Nc2nc(N)nc(CN3CCCCC3)n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K07 compound treatment 735592.0 26700.0 0.06 655629.0 -25200.0 -0.06 -6.0E-4 -0.0069 3119702 ChemDiv3_004099 CN/1C(=N)NC(=O)\C1=C\c2ccc(C)s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K08 compound treatment 1119509.0 411000.0 0.87 1222053.0 541000.0 1.23 1.4856 0.9856 3023298 ChemDiv3_004100 COc1ccc(C=C2C(=O)OC3(CCCCC3)OC2=O)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K09 compound treatment 1274503.0 566000.0 1.2 1159730.0 479000.0 1.09 1.6177 0.9988 3119703 ChemDiv3_004101 CCOc1cc(/C=C/2\C(=O)Nc3ccc(Br)cc23)ccc1OCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K10 compound treatment 1163593.0 455000.0 0.96 1422211.0 741000.0 1.69 1.8734 0.9649 1400389 ChemDiv3_004102 CCOC(=O)C1CCN(CC1)C(=O)N2c3ccccc3Sc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K11 compound treatment 1508526.0 800000.0 1.7 1501331.0 820000.0 1.87 2.5177 0.9989 1679244 ChemDiv3_004103 Cc1ccc(Nc2nc(C)cc(C)c2C(=O)N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K12 compound treatment 1426350.0 717000.0 1.52 1491724.0 811000.0 1.84 2.3791 0.9954 1721188 ChemDiv3_004104 CCCS(=O)(=O)N1CCN(CC1)C2CCN(CC2)C(=O)OCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K13 compound treatment 1084737.0 376000.0 0.8 1237697.0 557000.0 1.27 1.4586 0.9751 1612458 ChemDiv3_004105 CCn1c2ccccc2c3cc(NS(=O)(=O)c4ccccc4)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K14 compound treatment 1080063.0 371000.0 0.79 1252641.0 572000.0 1.3 1.4756 0.9711 1300482 ChemDiv3_004106 CN1C(=C(N2CCOCC2)c3ccccc3S1(=O)=O)C(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K15 compound treatment 1289543.0 581000.0 1.23 1358293.0 677000.0 1.54 1.9595 0.9938 3023329 ChemDiv3_004107 COc1ccc(cc1)C2=NN(C(C2)c3ccccc3OC)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K16 compound treatment 1204491.0 496000.0 1.05 1326824.0 646000.0 1.47 1.7814 0.9865 3119704 ChemDiv3_004108 NC1(N)OC(CN2C(=O)c3ccccc3C2=O)CS1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K17 compound treatment 1146439.0 438000.0 0.93 1205373.0 525000.0 1.19 1.4991 0.9923 1697884 ChemDiv3_004109 CCOC(=O)NC1CS(=O)(=O)C=C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K18 compound treatment 1328140.0 619000.0 1.31 1319744.0 639000.0 1.45 1.9554 0.9987 3119705 ChemDiv3_004110 CCN1C2=C(C(C3=C1CC(C)(C)CC3=O)c4ccc(OC)cc4)C(=O)CC(C)(C)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K19 compound treatment 1222470.0 514000.0 1.09 1156647.0 476000.0 1.08 1.5347 1.0 1179086 ChemDiv3_004111 O=S1(=O)CCC(C1)NC(=S)N2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K20 compound treatment 1090702.0 382000.0 0.81 1127121.0 446000.0 1.01 1.2898 0.9937 3119706 ChemDiv3_004112 CCCN1Cc2cccc(C(=O)N)c2C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K21 compound treatment 1182588.0 474000.0 1.0 909901.0 229000.0 0.52 1.0783 0.9532 1541504 ChemDiv3_004113 CC(C)NC(=S)SC1CS(=O)(=O)C=C1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K22 compound treatment 939760.0 231000.0 0.49 876080.0 195000.0 0.44 0.6599 0.9988 1280043 ChemDiv3_004114 Cc1cc(=O)oc2cc(OCc3cccc(F)c3)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K23 mock treatment 805475.0 96600.0 0.2 867282.0 186000.0 0.42 0.4445 0.9443 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 K24 mock treatment 550364.0 -159000.0 -0.34 624024.0 -56800.0 -0.13 -0.329 -0.9138 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L01 compound treatment 545876.0 -163000.0 -0.35 631132.0 -49700.0 -0.11 -0.3243 -0.8919 3119707 ChemDiv3_004115 COCCN1C(=O)N(C(=O)/C(=C\c2cn(CC(=O)OC)c3ccccc23)/C1=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L02 compound treatment 856539.0 148000.0 0.31 903609.0 223000.0 0.51 0.5794 0.9733 3023337 ChemDiv3_004116 CC1=[N+]([O-])C(C)(C)C(=[N+]1[O-])c2ccc(C)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L03 compound treatment 507451.0 -201000.0 -0.43 517684.0 -163000.0 -0.37 -0.5643 -0.9975 3119708 ChemDiv3_004117 CCOc1ccc(cc1c2nc(=O)c3n(C)nc(c3[nH]2)C(C)(C)C)S(=O)(=O)NCc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L04 compound treatment 1092228.0 383000.0 0.81 992468.0 312000.0 0.71 1.0756 0.9977 3023341 ChemDiv3_004118 [O-][n+]1cc(c2ccccc2)[n+]([O-])c3CCCCc31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L05 compound treatment 1014474.0 306000.0 0.65 1121121.0 440000.0 1.0 1.1658 0.9778 3023342 ChemDiv3_004119 CC(C)C(=O)Nc1cccc(c1)c2nc3ccccc3c(=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L06 compound treatment 1109216.0 400000.0 0.85 976486.0 296000.0 0.67 1.0753 0.9933 3119709 ChemDiv3_004120 CCc1ccc(OCCCn2cc(/C=C\3/C(=N)N4C=CSC4=NC3=O)c5ccccc25)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L07 compound treatment 1147426.0 439000.0 0.93 1030712.0 350000.0 0.8 1.2198 0.997 3023344 ChemDiv3_004121 CCSc1ncnc2c3cc4COC(C)(C)Cc4nc3sc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L08 compound treatment 1100314.0 391000.0 0.83 1230368.0 549000.0 1.25 1.4701 0.9802 1713113 ChemDiv3_004122 O=S1(=O)C=C(SCCN2CCOCC2)c3ccccc31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L09 compound treatment 2420913.0 1710000.0 3.63 2217070.0 1540000.0 3.49 5.036 0.9998 3023346 ChemDiv3_004123 CN(C)c1oc(nc1C#N)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L10 compound treatment 1144052.0 435000.0 0.92 1280007.0 599000.0 1.36 1.6155 0.982 3119710 ChemDiv3_004124 CCC1(COC(NC(=O)c2ccc(Cl)cc2Cl)(C(F)(F)F)C(F)(F)F)COC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L11 compound treatment 1185958.0 477000.0 1.01 1170579.0 490000.0 1.11 1.5024 0.9988 1380020 ChemDiv3_004125 CCC1CCc2c(C1)sc3ncnc(N4CCOCC4)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L12 compound treatment 1484182.0 775000.0 1.64 1729571.0 1050000.0 2.38 2.8481 0.9835 1709855 ChemDiv3_004126 CCOc1ccc(cc1)S(=O)(=O)Nc2nc3ccccc3nc2Nc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L13 compound treatment 1292759.0 584000.0 1.24 1208855.0 528000.0 1.2 1.724 0.9999 1688543 ChemDiv3_004127 Cc1cc(C)c(C)c(c1C)S(=O)(=O)N2CCN(CC2)c3ncnc4sc5CCCCc5c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L14 compound treatment 1167393.0 458000.0 0.97 1403677.0 723000.0 1.64 1.8493 0.9686 1554741 ChemDiv3_004128 COc1ccc2n(CCc3ccc(OC)c(OC)c3)c(C)c(C(=O)O)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L15 compound treatment 1094246.0 385000.0 0.82 1118175.0 437000.0 0.99 1.2807 0.9952 1579821 ChemDiv3_004129 COC(=O)CC1=C(C(=O)OC)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L16 compound treatment 1093560.0 385000.0 0.82 1203147.0 522000.0 1.19 1.4163 0.9832 3119711 ChemDiv3_004130 O/N=C/c1c(O)c(Br)cc2oc3CCCCc3c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L17 compound treatment 1088008.0 379000.0 0.8 1156258.0 475000.0 1.08 1.3326 0.9894 1421908 ChemDiv3_004131 O=c1n(CN2CCCCC2)nnc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L18 compound treatment 1239819.0 531000.0 1.13 1311947.0 631000.0 1.43 1.8104 0.9928 1535030 ChemDiv3_004132 COc1ccc(cc1)C(=O)n2nc3CC(C)(C)OCc3c2c4ccc(OC)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L19 compound treatment 1110475.0 402000.0 0.85 1141644.0 461000.0 1.05 1.3427 0.9947 3119712 ChemDiv3_004133 Cc1ccc(cc1)S(=O)(=O)N/2C(=O)C(C)(C)S\C2=N/CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L20 compound treatment 1017348.0 308000.0 0.65 934860.0 254000.0 0.58 0.8707 0.9981 1346941 ChemDiv3_004134 CN1CCN(Cc2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L21 compound treatment 1051933.0 343000.0 0.73 998774.0 318000.0 0.72 1.0253 1.0 3119713 ChemDiv3_004135 Cc1nnc(SCc2cccc(c2)C(=O)c3ccccc3)nc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L22 compound treatment 960851.0 252000.0 0.53 950426.0 270000.0 0.61 0.811 0.9977 3119714 ChemDiv3_004136 CC1CCN(CC1)/C(=N\S(=O)(=O)c2ccc(Br)cc2)/Nc3nc(C)cc(C)n3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L23 mock treatment 857089.0 148000.0 0.31 722198.0 41300.0 0.09 0.2886 0.8801 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 L24 mock treatment 527508.0 -181000.0 -0.38 559383.0 -121000.0 -0.28 -0.4672 -0.9868 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M01 compound treatment 594194.0 -115000.0 -0.24 633836.0 -47000.0 -0.11 -0.2476 -0.9319 3119869 ChemDiv3_004137 CCc1cc(C)cc(OCCn2cc(C=C3C(=O)NC(=O)NC3=O)c4ccccc24)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M02 compound treatment 1241505.0 533000.0 1.13 1078825.0 398000.0 0.9 1.4382 0.994 3023448 ChemDiv3_004138 CN1C(=O)C(=Cc2cn(CC=C)c3ccccc23)C(=O)N(C)C1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M03 compound treatment 1321241.0 612000.0 1.3 1141636.0 461000.0 1.05 1.6587 0.9943 3023450 ChemDiv3_004139 CCc1cccc2c1NC(=O)C32OCCO3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M04 compound treatment 1233024.0 524000.0 1.11 1112996.0 432000.0 0.98 1.4804 0.9981 1912757 ChemDiv3_004140 Cc1cc2/C(=C/c3ccco3)/OC(=O)c2c(=O)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M05 compound treatment 1542764.0 834000.0 1.77 1229641.0 549000.0 1.25 2.1322 0.9854 3119870 ChemDiv3_004141 CCSC1=N/C(=C\c2ccc(cc2)C(=O)O)/C(=O)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M06 compound treatment 1279089.0 570000.0 1.21 1226949.0 546000.0 1.24 1.7326 0.9999 3023453 ChemDiv3_004142 O=C(COc1ccccc1)N2CCN=C2c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M07 compound treatment 931687.0 223000.0 0.47 989370.0 309000.0 0.7 0.8299 0.9815 1181595 ChemDiv3_004143 CCC(=O)N1C(Oc2nc(SC)nnc2-c3ccccc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M08 compound treatment 901754.0 193000.0 0.41 859401.0 179000.0 0.41 0.5761 1.0 1618375 ChemDiv3_004144 S=C1NC(C2=C(N1)c3ccccc3CC2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M09 compound treatment 1272994.0 564000.0 1.2 1154786.0 474000.0 1.08 1.6075 0.9986 3023457 ChemDiv3_004145 CCCCN1C(=O)/C(=C/2\S/C(=N\c3ccc(Cl)cc3)/N(C)C2=O)/c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M10 compound treatment 1104870.0 396000.0 0.84 1060469.0 380000.0 0.86 1.2038 0.9999 3119871 ChemDiv3_004146 O=C(NCCCc1ccccc1)N2c3ccccc3Sc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M11 compound treatment 1294032.0 585000.0 1.24 1146908.0 466000.0 1.06 1.6264 0.9969 1406185 ChemDiv3_004147 Cc1cc(C)c2c(N=NN3CCCCCC3)n[nH]c2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M12 compound treatment 1091278.0 382000.0 0.81 1116532.0 436000.0 0.99 1.2736 0.9951 3119872 ChemDiv3_004148 Cc1cc(Br)ccc1NCc2ccc3OCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M13 compound treatment 1154998.0 446000.0 0.95 1101718.0 421000.0 0.96 1.3453 1.0 1438334 ChemDiv3_004149 Brc1ccc2oc(=O)c(cc2c1)C(=O)N3CCCc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M14 compound treatment 1321514.0 613000.0 1.3 979147.0 298000.0 0.68 1.3979 0.9541 3023462 ChemDiv3_004150 CN1C(=C(Nc2ccccc2C)c3ccccc3S1(=O)=O)C(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M15 compound treatment 1157814.0 449000.0 0.95 923625.0 243000.0 0.55 1.0632 0.9664 1567678 ChemDiv3_004151 COc1ccc(cc1)C2=NN(C(C2)c3ccc(C)cc3)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M16 compound treatment 1112273.0 403000.0 0.86 921733.0 241000.0 0.55 0.9919 0.9768 3023506 ChemDiv3_004152 OC(=O)CP(=S)(c1ccccc1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M17 compound treatment 271864.0 -437000.0 -0.93 245299.0 -436000.0 -0.99 -1.3554 -0.9994 1339249 ChemDiv3_004153 CCSC(=S)NC1CCS(=O)(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M18 compound treatment 1252292.0 543000.0 1.15 1090938.0 410000.0 0.93 1.4738 0.9945 3119873 ChemDiv3_004154 CCN1C2=C(C(C3=C1CCCC3=O)c4cccc(O)c4)C(=O)CCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M19 compound treatment 1221119.0 512000.0 1.09 976996.0 296000.0 0.67 1.2439 0.9736 1468946 ChemDiv3_004155 CN(C1CCS(=O)(=O)C1)C(=S)SC2CS(=O)(=O)C=C2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M20 compound treatment 1253258.0 544000.0 1.15 928454.0 248000.0 0.56 1.214 0.9455 1541732 ChemDiv3_004156 COC(=O)c1ccc(COc2ccc3c(cc(=O)oc3c2C)c4ccccc4)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M21 compound treatment 1199257.0 490000.0 1.04 895363.0 214000.0 0.49 1.0799 0.9405 1306134 ChemDiv3_004157 CN(C1CCCCC1)S(=O)(=O)C2CCS(=O)(=O)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M22 compound treatment 504915.0 -204000.0 -0.43 533435.0 -147000.0 -0.34 -0.5428 -0.9921 3119874 ChemDiv3_004158 CC1CN(CC(C)O1)C2=NC(=O)/C(=C/c3ccccc3)/S2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M23 mock treatment 1045538.0 337000.0 0.71 582637.0 -98200.0 -0.22 0.3467 0.4637 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 M24 mock treatment 483694.0 -225000.0 -0.48 537683.0 -143000.0 -0.33 -0.5678 -0.9826 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N01 compound treatment 459244.0 -250000.0 -0.53 472513.0 -208000.0 -0.47 -0.7092 -0.9985 3023511 ChemDiv3_004159 O=C1S/C(=C\c2ccc(o2)N3CCOCC3)/C(=O)N1c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N02 compound treatment 1015341.0 306000.0 0.65 1011595.0 331000.0 0.75 0.9911 0.9973 3119875 ChemDiv3_004160 CC1=[N+]([O-])C(C)(C)C(=[N+]1[O-])c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N03 compound treatment 1175178.0 466000.0 0.99 1018591.0 338000.0 0.77 1.2419 0.9922 3023512 ChemDiv3_004161 C1CCC2=C(C1)SC3=C(CCCC3)C2c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N04 compound treatment 1116910.0 408000.0 0.86 1190340.0 509000.0 1.16 1.4307 0.9897 1863423 ChemDiv3_004162 CSc1cccc(NC(=O)c2cc3c(ccc4ccccc34)o2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N05 compound treatment 1237494.0 529000.0 1.12 1256546.0 576000.0 1.31 1.7179 0.997 3023514 ChemDiv3_004163 O=C(ON1C(=O)c2ccccc2C1=O)C3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N06 compound treatment 1256508.0 548000.0 1.16 1213669.0 533000.0 1.21 1.6774 0.9998 1713635 ChemDiv3_004164 COC(=O)C1=C(C)Nc2c(C1c3cccc(OCc4ccccc4)c3)c(=O)n(C)c(=O)n2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N07 compound treatment 1283572.0 575000.0 1.22 1270262.0 589000.0 1.34 1.809 0.9989 3023519 ChemDiv3_004165 CCCCS(=O)(=O)N=C1NCN(CCO)CN1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N08 compound treatment 1234672.0 526000.0 1.11 1370978.0 690000.0 1.57 1.8976 0.986 3119876 ChemDiv3_004166 CC(C)(C)C1CCc2c(C1)sc3nc(oc(=O)c23)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N09 compound treatment 994600.0 286000.0 0.61 1197745.0 517000.0 1.18 1.2592 0.9525 3119877 ChemDiv3_004167 CCOC(=O)c1c(NC(=O)CC2S/C(=N\CC)/N(CC)C2=O)sc3CCCCc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N10 compound treatment 1041094.0 332000.0 0.7 1193569.0 513000.0 1.17 1.3222 0.9709 3023583 ChemDiv3_004168 COc1ccc(CNC(=N)N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N11 compound treatment 1107121.0 398000.0 0.84 1313778.0 633000.0 1.44 1.6144 0.9677 1550858 ChemDiv3_004169 CC1CCN(CC1)c2nnc(c3cccs3)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N12 compound treatment 1195009.0 486000.0 1.03 1456840.0 776000.0 1.76 1.9762 0.9672 1484112 ChemDiv3_004170 O=S(=O)(Nc1nc2ccccc2nc1NCCC3=CCCCC3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N13 compound treatment 1079667.0 371000.0 0.79 1266948.0 586000.0 1.33 1.498 0.9683 1570344 ChemDiv3_004171 CCc1nc(n2nnc3cc(C)c(C)cc23)c4c5CCCCc5sc4n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N14 compound treatment 881235.0 172000.0 0.37 1187344.0 506000.0 1.15 1.0726 0.8878 1352096 ChemDiv3_004172 CCOC(=O)c1c(C)n(C(C)C)c2ccc(OC(=O)c3ccccc3)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N15 compound treatment 991530.0 283000.0 0.6 1159375.0 479000.0 1.09 1.1929 0.9605 1652261 ChemDiv3_004173 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C32C(=O)N(CO)c4ccccc43)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N16 compound treatment 153432.0 -555000.0 -1.18 189171.0 -492000.0 -1.12 -1.6231 -0.9997 3023589 ChemDiv3_004174 CC(C)(C)c1cc2oc3CCCCc3c2c(/C=N/Cc4ccncc4)c1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N17 compound treatment 1075516.0 367000.0 0.78 1185168.0 504000.0 1.15 1.3603 0.9821 1176412 ChemDiv3_004175 Cc1onc(c1C(=O)NC(=S)NCc2ccco2)c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N18 compound treatment 1065298.0 356000.0 0.76 1188328.0 507000.0 1.15 1.3501 0.9789 1286690 ChemDiv3_004176 CC1(C)CC(CC(=O)N2CCOCC2)(CCO1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N19 compound treatment 1134659.0 426000.0 0.9 1088949.0 408000.0 0.93 1.2943 0.9999 1350975 ChemDiv3_004177 Cc1nn(C(=O)c2cccnc2)c(c1Sc3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N20 compound treatment 1054688.0 346000.0 0.73 1053783.0 373000.0 0.85 1.1179 0.9974 3119878 ChemDiv3_004178 CCCN(CCC)CN1CC(Cn2c3ccccc3c4ccccc24)OC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N21 compound treatment 899472.0 191000.0 0.4 610042.0 -70800.0 -0.16 0.1718 0.3951 1867988 ChemDiv3_004179 CC1CC(c2ccccc2)c3cc(C)ccc3N1S(=O)(=O)c4cccc(Cl)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N22 compound treatment 930312.0 221000.0 0.47 794959.0 114000.0 0.26 0.5153 0.9609 3119879 ChemDiv3_004180 Clc1ccc(cc1)C(=O)NC(=N)NCc2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N23 mock treatment 989943.0 281000.0 0.6 834062.0 153000.0 0.35 0.6676 0.9673 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 N24 mock treatment 558758.0 -150000.0 -0.32 607605.0 -73300.0 -0.17 -0.3428 -0.9544 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O01 compound treatment 470845.0 -238000.0 -0.5 455147.0 -226000.0 -0.51 -0.7197 -1.0 3023594 ChemDiv3_004181 CSc1nnc(c(O)n1)c2ccccc2N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O02 compound treatment 1142156.0 433000.0 0.92 986744.0 306000.0 0.7 1.1412 0.9906 3119880 ChemDiv3_004182 NC(=O)COc1ccc(C=C2C(=O)c3ccccc3C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O03 compound treatment 1330311.0 621000.0 1.32 1212641.0 532000.0 1.21 1.7864 0.9991 3023659 ChemDiv3_004183 CCc1ccc2NC(=O)/C(=C/3\NC(=S)NC3=O)/c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O04 compound treatment 896276.0 187000.0 0.4 1236503.0 556000.0 1.26 1.1741 0.8867 1537162 ChemDiv3_004184 COCc1cc(C)nc2sc(C(=O)N)c(N)c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O05 compound treatment 1142939.0 434000.0 0.92 1295401.0 615000.0 1.4 1.6386 0.9795 3023662 ChemDiv3_004185 COc1cccc(/C=C/2\N=C(SC)SC2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O06 compound treatment 1312053.0 603000.0 1.28 1273081.0 592000.0 1.35 1.8562 0.9997 3119881 ChemDiv3_004186 COc1cc(OC)cc(c1)C(=O)N2CCN=C2c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O07 compound treatment 369850.0 -339000.0 -0.72 396379.0 -284000.0 -0.65 -0.9656 -0.9986 3023663 ChemDiv3_004187 CCN(CC)c1ccc(/C=C/2\N(C)C(=N)NC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O08 compound treatment 1244417.0 536000.0 1.14 1317040.0 636000.0 1.45 1.8255 0.9928 3119882 ChemDiv3_004188 CC(O)CN1C(=O)/C(=C/c2ccc(o2)c3ccc(Br)cc3)/C(=C(C#N)C1=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O09 compound treatment 1369472.0 661000.0 1.4 1388197.0 707000.0 1.61 2.1274 0.9976 3023665 ChemDiv3_004189 CSC1=N/C(=C\c2ccc(Br)cc2)/C(=O)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O10 compound treatment 1258923.0 550000.0 1.17 1504941.0 824000.0 1.87 2.1493 0.974 1520777 ChemDiv3_004190 CN1C(=O)C(C2CC1(C)Oc3ccccc23)C(=O)NC(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O11 compound treatment 937445.0 229000.0 0.48 1063522.0 383000.0 0.87 0.9578 0.9618 1527053 ChemDiv3_004191 O=C(CN1CC(=O)Oc2ccccc12)OCC(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O12 compound treatment 1177677.0 469000.0 0.99 1488780.0 808000.0 1.84 2.0015 0.9584 3120033 ChemDiv3_004192 CCn1c2ccccc2c3cc(CNCCc4ccc(Cl)cc4)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O13 compound treatment 1170383.0 461000.0 0.98 1304901.0 624000.0 1.42 1.695 0.9835 1472912 ChemDiv3_004193 O=C(NC1(CCCCC1)C#N)c2cc3ccccc3oc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O14 compound treatment 1037273.0 328000.0 0.7 1343964.0 663000.0 1.51 1.5583 0.9384 3120034 ChemDiv3_004194 CCCN(CCC)C1=C(N(C)S(=O)(=O)c2ccccc12)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O15 compound treatment 1207694.0 499000.0 1.06 1279193.0 598000.0 1.36 1.7096 0.9922 3120035 ChemDiv3_004195 CS(=O)(=O)N1N=C(CC1c2cc3ccccc3nc2Cl)c4ccc(Br)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O16 compound treatment 1135734.0 427000.0 0.9 1393197.0 712000.0 1.62 1.785 0.9622 1484690 ChemDiv3_004196 OC(=O)CCNc1ncnc2sc3CCCCc3c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O17 compound treatment 1048826.0 340000.0 0.72 1216550.0 536000.0 1.22 1.3707 0.9686 3120036 ChemDiv3_004197 C=CCN1[C@H]2CS(=O)(=O)C[C@H]2NC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O18 compound treatment 958450.0 250000.0 0.53 1190960.0 510000.0 1.16 1.1941 0.9368 1564957 ChemDiv3_004198 CCOc1ccc(cc1)C2C3=C(CCCC3=O)NC4=C2C(=O)CCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O19 compound treatment 1342305.0 633000.0 1.34 1141279.0 460000.0 1.05 1.6897 0.9924 3023723 ChemDiv3_004199 CC1=CS(=O)(=O)CC1Sc2nc3ccccc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O20 compound treatment 1250661.0 542000.0 1.15 1255254.0 574000.0 1.31 1.7355 0.998 1479636 ChemDiv3_004200 Cc1oc(cc1COc2ccc3c4CCCCc4c(=O)oc3c2)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O21 compound treatment 1289868.0 581000.0 1.23 1015481.0 335000.0 0.76 1.4088 0.9732 3023725 ChemDiv3_004201 Cc1nc2sc3CCCCc3c2c4nnc(SCC(=O)c5ccccc5)n14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O22 compound treatment 1083832.0 375000.0 0.79 1055194.0 374000.0 0.85 1.1638 0.9994 3120037 ChemDiv3_004202 CC1CCC2(CC1)NN(C(=S)N2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O23 mock treatment 974839.0 266000.0 0.56 818274.0 137000.0 0.31 0.6196 0.9612 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 O24 mock treatment 382312.0 -327000.0 -0.69 437448.0 -243000.0 -0.55 -0.8809 -0.9938 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P01 compound treatment 480406.0 -228000.0 -0.48 379589.0 -301000.0 -0.68 -0.8269 -0.9856 3120038 ChemDiv3_004203 COCCN1C(=O)N(C(=O)/C(=C\c2cc(C)n(c2C)c3ccncc3)/C1=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P02 compound treatment 557984.0 -151000.0 -0.32 489728.0 -191000.0 -0.43 -0.5335 -0.9887 3023728 ChemDiv3_004204 CCc1c(C)[n+]([O-])c2CCCCCc2[n+]1[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P03 compound treatment 291474.0 -417000.0 -0.88 252644.0 -428000.0 -0.97 -1.3142 -0.9989 3023729 ChemDiv3_004205 COC(=O)c1ccc(OCC(O)Cn2c(C)[n+](C)c3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P04 compound treatment 755483.0 46600.0 0.1 691521.0 10700.0 0.02 0.087 0.8552 3120039 ChemDiv3_004206 CCn1cc(C(=O)O)c(=O)c2cc(F)c(cc12)N3CCN(CC3)C(=O)c4ccc(F)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P05 compound treatment 788190.0 79300.0 0.17 741362.0 60500.0 0.14 0.2161 0.995 3023733 ChemDiv3_004207 O=C(ON1C(=O)c2ccccc2C1=O)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P06 compound treatment 795224.0 86300.0 0.18 729876.0 49000.0 0.11 0.2082 0.9717 1192417 ChemDiv3_004208 COc1cc(cc(OC)c1OC)C2C3=C(CCCC3=O)Nc4[nH]c(=O)[nH]c(=O)c24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P07 compound treatment 732663.0 23800.0 0.05 696886.0 16000.0 0.04 0.0614 0.9873 3120040 ChemDiv3_004209 CC(=O)Nc1ccc(cc1)S(=O)(=O)N=C2NCN(CCOC(=O)c3ccccc3)CN2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P08 compound treatment 698089.0 -10800.0 -0.02 721911.0 41000.0 0.09 0.0498 0.5181 3023735 ChemDiv3_004210 COC(=O)c1c(C)nn(c1NC(=O)C(C)Oc2ccc(Cl)cc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P09 compound treatment 811202.0 102000.0 0.22 813139.0 132000.0 0.3 0.366 0.9871 1521251 ChemDiv3_004211 Cc1cc2nnn(c3nc(C)nc4sc5CCCCc5c34)c2cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P10 compound treatment 718390.0 9490.0 0.02 916212.0 235000.0 0.54 0.3926 0.7332 3023737 ChemDiv3_004212 CSc1nc(C)cc(NC(=O)N)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P11 compound treatment 1178404.0 470000.0 1.0 851703.0 171000.0 0.39 0.9784 0.9158 1165643 ChemDiv3_004213 CC(C)(C)c1ccc(cc1)c2cc3ccccn3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P12 compound treatment 676941.0 -32000.0 -0.07 850963.0 170000.0 0.39 0.2255 0.5745 1379043 ChemDiv3_004214 Fc1ccccc1Nc2nc3ccccc3nc2NS(=O)(=O)c4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P13 compound treatment 630961.0 -77900.0 -0.17 768671.0 87800.0 0.2 0.0243 0.0939 3120041 ChemDiv3_004215 Cc1cc(C(=O)CSc2ncnc3sc4CCCCc4c23)c(C)n1Cc5ccco5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P14 compound treatment 941889.0 233000.0 0.49 1204335.0 523000.0 1.19 1.1908 0.9241 3024070 ChemDiv3_004216 CN1C(=O)/C(=C/Nc2cccc(Cl)c2)/c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P15 compound treatment 980853.0 272000.0 0.58 1065584.0 385000.0 0.87 1.0262 0.9795 1257595 ChemDiv3_004217 OC(=O)CSc1nnc-2c(OC3(CCCC3)Nc4ccccc42)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P16 compound treatment 1172163.0 463000.0 0.98 1152438.0 472000.0 1.07 1.4526 0.999 3024074 ChemDiv3_004218 CN1C(=O)/C(=C\Nc2cccc(CO)c2)/c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P17 compound treatment 1019740.0 311000.0 0.66 1130831.0 450000.0 1.02 1.1893 0.9774 3120042 ChemDiv3_004219 Cc1ccc(Oc2ncnc3sccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P18 compound treatment 1076386.0 367000.0 0.78 1177921.0 497000.0 1.13 1.35 0.9835 3024079 ChemDiv3_004220 CC1=N/C(=C/c2cc3ccccc3nc2Sc4ccc(C)cc4)/C(=O)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P19 compound treatment 866225.0 157000.0 0.33 929314.0 248000.0 0.56 0.6353 0.9684 1244804 ChemDiv3_004221 COc1ccc(cc1OC)C(=O)Nn2c(C)nnc2n3nc(C)cc3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P20 compound treatment 993081.0 284000.0 0.6 939991.0 259000.0 0.59 0.8426 0.9999 3120043 ChemDiv3_004222 CC(C)CN(CC(C)C)CN1CC(COc2ccccc2C)OC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P21 compound treatment 682840.0 -26100.0 -0.06 808566.0 128000.0 0.29 0.1662 0.5625 3023284 ChemDiv3_004223 COC(=O)C1=CN(C=C(C1c2cccc(OC)c2)C(=O)OC)C3(CC4CC5CC(C4)C3)C5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P22 compound treatment 505293.0 -204000.0 -0.43 531308.0 -150000.0 -0.34 -0.5456 -0.993 1820755 ChemDiv3_004224 O=C(CSc1nnnn1c2ccccc2)N3c4ccccc4CCc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P23 mock treatment 526742.0 -182000.0 -0.39 599445.0 -81400.0 -0.19 -0.404 -0.9433 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2012 P24 mock treatment 432862.0 -276000.0 -0.59 490918.0 -190000.0 -0.43 -0.7192 -0.9888 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A01 compound treatment 439402.0 -358000.0 -0.76 326672.0 -391000.0 -0.89 -1.1652 -0.9968 1871572 ChemDiv3_004225 O=C(CSC(=S)N1CCCCC1)N2c3ccccc3CCc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A02 compound treatment 560739.0 -236000.0 -0.5 380297.0 -338000.0 -0.77 -0.8971 -0.9785 3120044 ChemDiv3_004226 CCOc1ccc2cc(C3CC(=NN3S(=O)(=O)c4ccccc4)c5ccco5)c(Cl)nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A03 compound treatment 684502.0 -112000.0 -0.24 630756.0 -87300.0 -0.2 -0.3089 -0.9959 1572427 ChemDiv3_004227 Cc1nn2c(c1C(=S)Nc3ccccc3)n(C)c4ccccc42 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A04 compound treatment 767280.0 -29600.0 -0.06 667518.0 -50600.0 -0.11 -0.1257 -0.9596 1416443 ChemDiv3_004228 OC1CCC(CC1)n2c(nc(=S)c3CCCCc32)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A05 compound treatment 535450.0 -261000.0 -0.55 602466.0 -116000.0 -0.26 -0.5778 -0.9419 1490702 ChemDiv3_004229 CS(=O)(=O)c1ccc2nc(NC(=O)Oc3ccccc3)sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A06 compound treatment 555211.0 -242000.0 -0.51 461791.0 -256000.0 -0.58 -0.7744 -0.9979 3023292 ChemDiv3_004230 Cc1[nH]c2ccccc2c1C(Nc3ccccn3)c4ccc(cc4)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A07 compound treatment 291490.0 -505000.0 -1.07 299541.0 -419000.0 -0.95 -1.4305 -0.9982 3120045 ChemDiv3_004231 Cn1c(=N)n(CCOc2ccccc2Cl)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A08 compound treatment 1911951.0 1120000.0 2.36 1020710.0 303000.0 0.69 2.158 0.8765 1873167 ChemDiv3_004232 CC(Nc1cc(C)c(C#N)c2nc3ccccc3n12)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A09 compound treatment 595716.0 -201000.0 -0.43 464936.0 -253000.0 -0.58 -0.7086 -0.9891 3023296 ChemDiv3_004233 CCn1c2/C(=N/O)/CCCc2c3cc(ccc13)C4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A10 compound treatment 714452.0 -82500.0 -0.17 466177.0 -252000.0 -0.57 -0.5286 -0.8827 1873230 ChemDiv3_004234 COc1ccc(CCNc2c(CC=C)c(C)c(C#N)c3nc4ccccc4n23)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A11 compound treatment 540556.0 -256000.0 -0.54 535561.0 -183000.0 -0.42 -0.6777 -0.9911 3023348 ChemDiv3_004235 O/N=C/1\C(=O)N(CN2CCCCC2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A12 compound treatment 612054.0 -185000.0 -0.39 529021.0 -189000.0 -0.43 -0.5811 -0.9989 1286346 ChemDiv3_004236 COc1ccc(cc1)c2nn(cc2C(=O)N(C)C)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A13 compound treatment 590839.0 -206000.0 -0.44 588330.0 -130000.0 -0.3 -0.5175 -0.9817 1242885 ChemDiv3_004237 O=C(N1CCCCC1)N2c3ccccc3Sc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A14 compound treatment 488302.0 -309000.0 -0.65 632580.0 -85500.0 -0.19 -0.6001 -0.8792 1191358 ChemDiv3_004238 CCOC(=O)Nc1cc(C(=O)OCC)c(C)nc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A15 compound treatment 764913.0 -32000.0 -0.07 827902.0 110000.0 0.25 0.1285 0.4969 1469246 ChemDiv3_004239 CC1(C)CC2(CCO1)OC(=O)CC2C(=O)NCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A16 compound treatment 845914.0 49000.0 0.1 714228.0 -3870.0 -0.01 0.0672 0.6449 1401727 ChemDiv3_004240 CNS(=O)(=O)c1ccc2[nH]c(=O)[nH]c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A17 compound treatment 584708.0 -212000.0 -0.45 468931.0 -249000.0 -0.57 -0.7187 -0.9935 1494565 ChemDiv3_004241 COc1ccc(cc1)C(C2=C(O)CC(C)(C)CC2=O)c3c(C)[nH]c4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A18 compound treatment 189796.0 -607000.0 -1.29 141435.0 -577000.0 -1.31 -1.8372 -1.0 1028707 ChemDiv3_004242 C(N1CCN(Cc2c[nH]c3ccccc23)CC1)c4c[nH]c5ccccc45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A19 compound treatment 1289830.0 493000.0 1.04 807073.0 89000.0 0.2 0.8819 0.8286 1584523 ChemDiv3_004243 COc1ccc(cc1OC)c2n[nH]c(=S)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A20 compound treatment 732752.0 -64200.0 -0.14 508806.0 -209000.0 -0.48 -0.4327 -0.8742 1669366 ChemDiv3_004244 COc1ccc(cc1)c2nc3ccccc3n2CCOc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A21 compound treatment 785596.0 -11300.0 -0.02 429970.0 -288000.0 -0.66 -0.4802 -0.7325 3023360 ChemDiv3_004245 Cc1ccc(NC(=O)CC(NCC2CCCO2)C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A22 compound treatment 228128.0 -569000.0 -1.21 218793.0 -499000.0 -1.14 -1.6553 -0.9995 1639148 ChemDiv3_004246 Brc1ccc(NC(=O)CCNS(=O)(=O)c2ccccc2)c(c1)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A23 mock treatment 610012.0 -187000.0 -0.4 415288.0 -303000.0 -0.69 -0.767 -0.9656 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 A24 mock treatment 542469.0 -254000.0 -0.54 306949.0 -411000.0 -0.93 -1.0424 -0.9659 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B01 compound treatment 463774.0 -333000.0 -0.71 381873.0 -336000.0 -0.76 -1.0399 -0.9992 1208457 ChemDiv3_004247 Cc1ccc(cc1C)C(=O)COC(=O)C2c3ccccc3Oc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B02 compound treatment 805720.0 8800.0 0.02 644778.0 -73300.0 -0.17 -0.1047 -0.6241 3023400 ChemDiv3_004248 Cc1ccc(cc1)C(=O)/C=C/2\NC(=NC2=O)NS(=O)(=O)c3ccc(N)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B03 compound treatment 1001151.0 204000.0 0.43 1165165.0 447000.0 1.02 1.0249 0.9277 3120180 ChemDiv3_004249 CC(NC(=O)c1cc2c(=O)n3cccc(C)c3nc2n(CC4CCCO4)c1=N)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B04 compound treatment 1254500.0 458000.0 0.97 1116020.0 398000.0 0.9 1.3256 0.9994 3120181 ChemDiv3_004250 CCC1CCc2nc3sc(C(=O)Nc4cc(Cl)ccc4OC)c(N)c3cc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B05 compound treatment 1121334.0 324000.0 0.69 1640472.0 922000.0 2.1 1.9692 0.8922 3023403 ChemDiv3_004251 CCCn1c(=N)c(cc2c(=O)n3cc(C)ccc3nc12)C(=O)NC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B06 compound treatment 1012138.0 215000.0 0.46 866197.0 148000.0 0.34 0.5607 0.9888 3120182 ChemDiv3_004252 Cn1cc(C2Nc3sc4CCCCc4c3C(=N2)O)c5ccccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B07 compound treatment 833443.0 36500.0 0.08 694509.0 -23600.0 -0.05 0.0168 0.1787 3023406 ChemDiv3_004253 CCN/1C(=O)C(S\C1=N\c2ccc(cc2)C(=O)OC)C(O)c3cc(OC)ccc3OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B08 compound treatment 904366.0 107000.0 0.23 760531.0 42400.0 0.1 0.2293 0.9269 3120183 ChemDiv3_004254 COc1cc(/C=C/2\NC(=S)N(C)C2=O)ccc1OCc3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B09 compound treatment 982003.0 185000.0 0.39 960625.0 243000.0 0.55 0.6673 0.9861 1671194 ChemDiv3_004255 Cc1cccc(c1)C(=O)Nc2nc3CC(C)(C)CC(=O)c3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B10 compound treatment 1044171.0 247000.0 0.52 967457.0 249000.0 0.57 0.7715 0.9992 3120184 ChemDiv3_004256 OC(=O)CCc1nc2cc(ccc2[nH]1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B11 compound treatment 1000612.0 204000.0 0.43 833281.0 115000.0 0.26 0.4905 0.9713 3120185 ChemDiv3_004257 FC(F)(F)c1cc(nc(n1)S(=O)(=O)Cc2cccc(Cl)c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B12 compound treatment 1137638.0 341000.0 0.72 919805.0 202000.0 0.46 0.835 0.976 1719820 ChemDiv3_004258 CC1(C)C2CCC1(C)c3c2c(nn3c4ccccc4)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B13 compound treatment 1012935.0 216000.0 0.46 857781.0 140000.0 0.32 0.5484 0.984 3120186 ChemDiv3_004259 C=CCN1C2=NC(=O)CN2c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B14 compound treatment 1072925.0 276000.0 0.59 906791.0 189000.0 0.43 0.7171 0.9884 1317554 ChemDiv3_004260 CC(C)(C)Nc1nc2nonc2nc1NC(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B15 compound treatment 913937.0 117000.0 0.25 965588.0 247000.0 0.56 0.5733 0.9323 3120187 ChemDiv3_004261 CCCn1c(SCCCc2ccccc2)nc3n(C)c(=O)[nH]c(=O)c13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B16 compound treatment 807478.0 10600.0 0.02 952373.0 234000.0 0.53 0.3925 0.7362 3120188 ChemDiv3_004262 COC(=O)c1ccc(cc1)[C@@H]2Nc3c(C)cccc3[C@@H]4C=CC[C@@H]42 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B17 compound treatment 296845.0 -500000.0 -1.06 325172.0 -393000.0 -0.89 -1.3813 -0.9964 1361311 ChemDiv3_004263 CCOC(=O)c1cc2c(C)n(c(C)c2cc(C(=O)OCC)c1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B18 compound treatment 1027017.0 230000.0 0.49 816966.0 98900.0 0.22 0.5039 0.9381 3120189 ChemDiv3_004264 OC(=O)c1ccc(CSc2nnc(COc3ccc(Cl)cc3Cl)o2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B19 compound treatment 1114239.0 317000.0 0.67 919029.0 201000.0 0.46 0.7987 0.9822 1150810 ChemDiv3_004265 COc1ccc(OCC(O)CNC(=O)c2ccccc2C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B20 compound treatment 1013344.0 216000.0 0.46 999435.0 281000.0 0.64 0.7767 0.9867 3120190 ChemDiv3_004266 S=C(Nc1ccc2nsnc2c1)N3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B21 compound treatment 1261342.0 464000.0 0.98 1042952.0 325000.0 0.74 1.2184 0.99 3120191 ChemDiv3_004267 NC(=O)c1c(NCCO)nc(cc1C(F)(F)F)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B22 compound treatment 1137038.0 340000.0 0.72 1070435.0 352000.0 0.8 1.0763 0.9986 3023474 ChemDiv3_004268 OC(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(OC(=O)c4cccs4)cc3)/C2=O)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B23 mock treatment 911685.0 115000.0 0.24 961725.0 244000.0 0.55 0.5637 0.9318 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 B24 mock treatment 486999.0 -310000.0 -0.66 401693.0 -316000.0 -0.72 -0.9732 -0.999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C01 compound treatment 592719.0 -204000.0 -0.43 416677.0 -301000.0 -0.69 -0.7907 -0.9755 3023414 ChemDiv3_004269 Cc1cc(O)nc(NC(=N)Nc2ccccc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C02 compound treatment 953376.0 156000.0 0.33 951793.0 234000.0 0.53 0.6102 0.9743 3120192 ChemDiv3_004270 Cc1ccc(cc1)C2=NN(C(C2)c3ccc4nccnc4c3)S(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C03 compound treatment 1012386.0 215000.0 0.46 939372.0 221000.0 0.5 0.6787 0.9988 3023419 ChemDiv3_004271 COc1ccc(C=C2C(=O)OC(C)(OC2=O)C(C)(C)C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C04 compound treatment 998740.0 202000.0 0.43 949854.0 232000.0 0.53 0.6751 0.9947 1343660 ChemDiv3_004272 NS(=O)(=O)c1ccc(CCn2c(nc(=S)c3CCCCc32)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C05 compound treatment 1119396.0 322000.0 0.68 1004822.0 287000.0 0.65 0.9444 0.9997 1645275 ChemDiv3_004273 CCOC(=O)c1cnc2c(C)c(Cl)ccc2c1Nc3cc(C)ccc3OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C06 compound treatment 1194126.0 397000.0 0.84 971120.0 253000.0 0.58 1.0022 0.9827 3120193 ChemDiv3_004274 COc1cccc(c1)C(Nc2ccccn2)c3c(C)[nH]c4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C07 compound treatment 193219.0 -604000.0 -1.28 178504.0 -540000.0 -1.23 -1.7724 -0.9998 1260066 ChemDiv3_004275 N=c1n(CCOc2ccccc2)c3ccccc3n1Cc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C08 compound treatment 302893.0 -494000.0 -1.05 353777.0 -364000.0 -0.83 -1.3263 -0.9933 1873175 ChemDiv3_004276 CCc1c(C)c(C#N)c2nc3ccccc3n2c1NCCC(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C09 compound treatment 1284322.0 487000.0 1.03 1066076.0 348000.0 0.79 1.2901 0.9913 3120194 ChemDiv3_004277 N#CCCN1CCn2c3ccc(cc3c4cccc1c24)C5CCCCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C10 compound treatment 764013.0 -32900.0 -0.07 802076.0 84000.0 0.19 0.0857 0.4215 3120195 ChemDiv3_004278 CC1CCN(CC1)c2ncnc3n(Cc4ccc(Cl)cc4)ncc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C11 compound treatment 945934.0 149000.0 0.32 717435.0 -663.0 0.0 0.2223 0.7037 3023477 ChemDiv3_004279 COc1cc(ccc1O)c2nc3c([nH]2)c4ccccc4c5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C12 compound treatment 1115144.0 318000.0 0.67 1080885.0 363000.0 0.82 1.0603 0.995 3120196 ChemDiv3_004280 COc1ccc(cc1OC)c2nn(cc2C(=O)Oc3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C13 compound treatment 1261026.0 464000.0 0.98 1087131.0 369000.0 0.84 1.289 0.9969 1388153 ChemDiv3_004281 Cc1ccc(NC(=O)N2c3ccccc3Sc4ccccc24)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C14 compound treatment 1161762.0 365000.0 0.77 994153.0 276000.0 0.63 0.9907 0.9946 3120197 ChemDiv3_004282 COC(=O)c1ccc(O)c(/C=N/N(CCO)C2=NS(=O)(=O)c3ccccc23)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C15 compound treatment 1224228.0 427000.0 0.91 1023743.0 306000.0 0.69 1.1319 0.9914 1407736 ChemDiv3_004283 COC(=O)c1c(C)c(C)sc1NC(=O)CC2Nc3cc(C)c(C)cc3NC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C16 compound treatment 1225956.0 429000.0 0.91 972557.0 254000.0 0.58 1.0522 0.9761 3023484 ChemDiv3_004284 CC/1=NN(C(=O)\C1=C/C=C\c2ccccc2)c3ccc(cc3)S(=O)(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C17 compound treatment 453112.0 -344000.0 -0.73 418719.0 -299000.0 -0.68 -0.9967 -0.9994 1706298 ChemDiv3_004285 CCOC(=O)c1c(C)oc2c1c3CN(CCc4ccccc4)COc3c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C18 compound treatment 1313356.0 516000.0 1.09 1032287.0 314000.0 0.71 1.2793 0.9786 1247453 ChemDiv3_004286 CCOC(=O)c1ccc(NCc2ccc(cc2)N(C)C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C19 compound treatment 290667.0 -506000.0 -1.07 239330.0 -479000.0 -1.09 -1.5286 -1.0 1444763 ChemDiv3_004287 CCOC(=O)c1c(C)n(c2ccc(C)cc2)c3ccc(OCC(O)CNCC4CCCO4)cc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C20 compound treatment 1125658.0 329000.0 0.7 1070222.0 352000.0 0.8 1.0589 0.9976 3024350 ChemDiv3_004288 Nc1ccc(cc1)c2nc3ccccc3n2CCCOc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C21 compound treatment 1168196.0 371000.0 0.79 983774.0 266000.0 0.6 0.9837 0.9915 3024351 ChemDiv3_004289 Cc1cc(C)cc(NC(=O)CC(NCc2cccnc2)C(=O)O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C22 compound treatment 169988.0 -627000.0 -1.33 124740.0 -593000.0 -1.35 -1.8937 -1.0 1315276 ChemDiv3_004290 CC(C)(C)SCC(O)Cn1c2ccc(Cl)cc2c3cc(Cl)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C23 mock treatment 1037519.0 241000.0 0.51 716441.0 -1660.0 0.0 0.358 0.7019 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 C24 mock treatment 756680.0 -40200.0 -0.09 846746.0 129000.0 0.29 0.1465 0.4808 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D01 compound treatment 462889.0 -334000.0 -0.71 466919.0 -251000.0 -0.57 -0.9045 -0.9943 3024352 ChemDiv3_004291 OC(=O)c1ccc(cc1)c2nnc(o2)c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D02 compound treatment 574389.0 -223000.0 -0.47 564516.0 -154000.0 -0.35 -0.5805 -0.989 3024353 ChemDiv3_004292 OC1=C(C(=O)c2ccc(F)cc2)C3(OC1=O)C(=O)c4ccccc4C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D03 compound treatment 785134.0 -11800.0 -0.02 837269.0 119000.0 0.27 0.1739 0.6392 3024354 ChemDiv3_004293 COC(=O)c1cc2c(=O)n3cccc(C)c3nc2n(CC=C)c1=N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D04 compound treatment 740019.0 -56900.0 -0.12 679388.0 -38700.0 -0.09 -0.1475 -0.988 3024355 ChemDiv3_004294 CN1CCc2nc(SCc3cccc(Cl)c3)c(C#N)cc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D05 compound treatment 2554462.0 1760000.0 3.73 2528232.0 1810000.0 4.12 5.5447 0.9988 3120198 ChemDiv3_004295 CCCn1c(=N)c(cc2c(=O)n3ccccc3nc12)C(=O)NCC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D06 compound treatment 138442.0 -658000.0 -1.4 131501.0 -587000.0 -1.33 -1.9301 -0.9997 3024356 ChemDiv3_004296 CCc1ccc(Nc2cc(=O)oc3ccccc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D07 compound treatment 955583.0 159000.0 0.34 865815.0 148000.0 0.34 0.4753 1.0 3120199 ChemDiv3_004297 O=S(=O)(Nc1ccccc1)c2ccc3oc4ccc(cc4c3c2)S(=O)(=O)Nc5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D08 compound treatment 922118.0 125000.0 0.27 875582.0 157000.0 0.36 0.4409 0.9891 3024357 ChemDiv3_004298 CC(Sc1nc2ccc(Br)cc2[nH]1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D09 compound treatment 898090.0 101000.0 0.21 873572.0 155000.0 0.35 0.4016 0.9713 3117747 ChemDiv3_004299 O=C(Nc1ccc(cc1)S(=O)(=O)NCCc2ccccc2)C3c4ccccc4Oc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D10 compound treatment 919477.0 123000.0 0.26 1025388.0 307000.0 0.7 0.6777 0.9092 3024358 ChemDiv3_004300 COC(=O)c1ccccc1NC(=O)CSc2nnc(CSc3nc(C)cc(C)n3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D11 compound treatment 917953.0 121000.0 0.26 838948.0 121000.0 0.27 0.3757 0.9994 3117748 ChemDiv3_004301 COc1ccc(OC)c2c(cc(nc12)C(F)(F)F)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D12 compound treatment 863277.0 66400.0 0.14 1021936.0 304000.0 0.69 0.5879 0.834 3024359 ChemDiv3_004302 CCOC(=O)CC1=NN=C(N)SC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D13 compound treatment 727669.0 -69200.0 -0.15 700350.0 -17700.0 -0.04 -0.1323 -0.8692 3117749 ChemDiv3_004303 CN(C)CCCn1c(=N)n(CC(O)C(C)(C)C)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D14 compound treatment 997112.0 200000.0 0.42 1026560.0 308000.0 0.7 0.796 0.9711 1785039 ChemDiv3_004304 CCOC(=O)/C=C/1\CC(=O)Nc2cc(C)c(C)cc2N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D15 compound treatment 1102055.0 305000.0 0.65 996988.0 279000.0 0.63 0.9058 1.0 3117750 ChemDiv3_004305 Fc1ccc(cc1)C(=O)N2CCCCC(Sc3ncnc4sc5CCCc5c34)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D16 compound treatment 982741.0 186000.0 0.39 956737.0 239000.0 0.54 0.6622 0.9876 3117751 ChemDiv3_004306 COc1cc(/C=C\2/C(=O)ON=C2c3ccccc3)ccc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D17 compound treatment 565573.0 -231000.0 -0.49 543772.0 -174000.0 -0.4 -0.627 -0.9944 1307290 ChemDiv3_004307 Oc1c(ccc2cccnc12)C(N3CCCCC3)c4ccccc4Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D18 compound treatment 1220906.0 424000.0 0.9 1185448.0 467000.0 1.06 1.3869 0.9965 3117752 ChemDiv3_004308 Cn1c(=O)n(C)c2cc(/C=C\3/NC(=O)NC3=O)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D19 compound treatment 1064549.0 268000.0 0.57 1061784.0 344000.0 0.78 0.9537 0.9876 1180264 ChemDiv3_004309 OC(CN1C(=O)c2ccccc2S1(=O)=O)Cn3c4ccccc4c5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D20 compound treatment 938555.0 142000.0 0.3 1032025.0 314000.0 0.71 0.717 0.926 3024361 ChemDiv3_004310 CCN(CC)C(=S)Nc1ccc2nsnc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D21 compound treatment 1025175.0 228000.0 0.48 984043.0 266000.0 0.6 0.7697 0.9939 1118442 ChemDiv3_004311 Fc1cn(C2CCCO2)c(=O)n(Cc3ccc(Cl)cc3)c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D22 compound treatment 830075.0 33200.0 0.07 870817.0 153000.0 0.35 0.2952 0.8334 3117753 ChemDiv3_004312 Cc1ccc(cc1)C2=NCN(C(=S)N2)c3ccc(cc3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D23 mock treatment 749027.0 -47900.0 -0.1 781301.0 63200.0 0.14 0.0298 0.1695 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 D24 mock treatment 686570.0 -110000.0 -0.23 489890.0 -228000.0 -0.52 -0.5323 -0.9353 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E01 compound treatment 723418.0 -73500.0 -0.16 536909.0 -181000.0 -0.41 -0.4015 -0.9115 3117754 ChemDiv3_004313 COCc1cc(=O)[nH]c(N/C(=N/C(=O)c2ccc(C)cc2)/Nc3cccc(Cl)c3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E02 compound treatment 1021677.0 225000.0 0.48 795429.0 77300.0 0.18 0.4612 0.9082 3024362 ChemDiv3_004314 CCS(=O)(=O)N1N=C(CC1c2cc3cc4OCCOc4cc3nc2Cl)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E03 compound treatment 1186662.0 390000.0 0.83 913251.0 195000.0 0.44 0.898 0.9575 1488515 ChemDiv3_004315 Cc1c(N)c2c3CCCCc3sc2nc1c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E04 compound treatment 1099082.0 302000.0 0.64 1026896.0 309000.0 0.7 0.9494 0.999 3117755 ChemDiv3_004316 Cc1ccc(cc1)S(=O)(=O)NC2C(Sc3ccccn3)c4cccc5cccc2c45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E05 compound treatment 1186074.0 389000.0 0.82 935914.0 218000.0 0.5 0.9335 0.9702 1192256 ChemDiv3_004317 CCn1cc(C(=O)O)c(=O)c2cc(F)c(F)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E06 compound treatment 1276242.0 479000.0 1.02 1024135.0 306000.0 0.7 1.2105 0.9829 3024363 ChemDiv3_004318 CCOC(=S)SCc1cn2ccc(C)cc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E07 compound treatment 1216515.0 420000.0 0.89 976436.0 258000.0 0.59 1.0443 0.9797 3117756 ChemDiv3_004319 CCC(C)c1ccc(NC(=O)C2CN(C(=O)C2)c3ccc(C)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E08 compound treatment 1462628.0 666000.0 1.41 1372573.0 654000.0 1.49 2.0501 0.9997 3024364 ChemDiv3_004320 Cc1c(Cc2ccc(Cl)cc2)c(=O)n3c4ccccc4[nH]c3c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E09 compound treatment 1293576.0 497000.0 1.05 1040489.0 322000.0 0.73 1.2628 0.9843 3117757 ChemDiv3_004321 Cc1cc(C)c2c(n1)sc3c(SCc4ccccc4)nc(C)nc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E10 compound treatment 1311197.0 514000.0 1.09 1032631.0 315000.0 0.72 1.2766 0.9791 3117758 ChemDiv3_004322 Cc1ccc(s1)S(=O)(=O)N2CCC(CC2)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E11 compound treatment 1493308.0 696000.0 1.48 1125796.0 408000.0 0.93 1.6993 0.9749 1202603 ChemDiv3_004323 O=C(Nc1cccc2CCCCc12)N3c4ccccc4Sc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E12 compound treatment 1150732.0 354000.0 0.75 978870.0 261000.0 0.59 0.9496 0.9932 3117759 ChemDiv3_004324 COC(=O)c1cn(nc1c2cccnc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E13 compound treatment 1418757.0 622000.0 1.32 996208.0 278000.0 0.63 1.3793 0.9434 3117760 ChemDiv3_004325 Cc1ccccc1n2c(S)nc3nc4CCCCc4cc3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E14 compound treatment 1103421.0 307000.0 0.65 1172675.0 455000.0 1.03 1.1903 0.975 3024365 ChemDiv3_004326 O=C(OCCNC1=NS(=O)(=O)c2ccccc12)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E15 compound treatment 1427362.0 630000.0 1.34 1046213.0 328000.0 0.75 1.4725 0.9621 1253252 ChemDiv3_004327 COc1ccc(cc1)C2C3C(ON2c4ccccc4)C(=O)NC3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E16 compound treatment 1491197.0 694000.0 1.47 1066194.0 348000.0 0.79 1.6004 0.9577 3024366 ChemDiv3_004328 CCCCC1(C)OC(=O)C(=Cc2ccc(OCC)c(OC)c2)C(=O)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E17 compound treatment 175122.0 -622000.0 -1.32 196786.0 -521000.0 -1.19 -1.7702 -0.9986 1304057 ChemDiv3_004329 CCCCN1COc2c(C1)cc(Cl)c3cccnc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E18 compound treatment 1235346.0 438000.0 0.93 984838.0 267000.0 0.61 1.086 0.9786 1268625 ChemDiv3_004330 CC(C)Oc1ccc(NP(=O)(C)Oc2cc(C)cc(C)c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E19 compound treatment 1376347.0 579000.0 1.23 1182075.0 464000.0 1.05 1.6145 0.9971 1125399 ChemDiv3_004331 O=C1CC(=O)N(N1c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E20 compound treatment 1133207.0 336000.0 0.71 1175552.0 457000.0 1.04 1.2395 0.983 1655164 ChemDiv3_004332 COC(=O)c1ccc(cc1)N2C(=O)C3ON(C(C3C2=O)c4ccc(F)cc4)c5ccccc5C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E21 compound treatment 1357345.0 560000.0 1.19 1132675.0 415000.0 0.94 1.5066 0.9934 3024367 ChemDiv3_004333 Cc1c(Cl)cccc1NC(=O)CC(NCc2ccccn2)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E22 compound treatment 1215827.0 419000.0 0.89 974053.0 256000.0 0.58 1.0394 0.979 3117761 ChemDiv3_004334 CN(C)c1ccc(cc1)C2CC(=NN2S(=O)(=O)C)c3ccc(Br)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E23 mock treatment 1072029.0 275000.0 0.58 859664.0 142000.0 0.32 0.64 0.9607 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 E24 mock treatment 765742.0 -31200.0 -0.07 514864.0 -203000.0 -0.46 -0.3735 -0.8001 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F01 compound treatment 280886.0 -516000.0 -1.09 280602.0 -437000.0 -0.99 -1.4769 -0.9989 3024368 ChemDiv3_004335 Cc1cc(/C=N/n2cnnc2)c(C)n1c3cccc(c3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F02 compound treatment 901353.0 104000.0 0.22 877111.0 159000.0 0.36 0.4122 0.9723 3117762 ChemDiv3_004336 CN(C)C(=N)c1nn[nH]c1SCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F03 compound treatment 1723846.0 927000.0 1.97 1854470.0 1140000.0 2.58 3.2164 0.9909 1558689 ChemDiv3_004337 C=CCn1c(=N)c(C#N)cc2c(=O)n3ccccc3nc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F04 compound treatment 1114545.0 318000.0 0.67 898461.0 180000.0 0.41 0.7661 0.9717 3117763 ChemDiv3_004338 Cc1cc(nc2sc(C(=O)c3cccc(Cl)c3)c(N)c12)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F05 compound treatment 2528782.0 1730000.0 3.67 2524546.0 1810000.0 4.11 5.5002 0.9984 3117764 ChemDiv3_004339 CCCn1c(=N)c(cc2c(=O)n3ccccc3nc12)C(=O)NC4CCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F06 compound treatment 182865.0 -614000.0 -1.3 178730.0 -539000.0 -1.23 -1.7876 -0.9996 3024369 ChemDiv3_004340 Cc1cc(C)cc(Nc2cc(=O)oc3ccccc23)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F07 compound treatment 1178553.0 382000.0 0.81 984499.0 266000.0 0.61 1.0004 0.9898 3024370 ChemDiv3_004341 CNS(=O)(=O)c1ccc2oc3ccc(cc3c2c1)S(=O)(=O)NC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F08 compound treatment 926851.0 130000.0 0.28 1020668.0 303000.0 0.69 0.6812 0.9193 3117765 ChemDiv3_004342 CCCOc1ccc(OCCSc2nc(=O)cc(N)[nH]2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F09 compound treatment 1079317.0 282000.0 0.6 962919.0 245000.0 0.56 0.8169 0.9993 3117766 ChemDiv3_004343 Cc1ccc(NC(=N)Nc2nc(cc(n2)C(F)(F)F)C(F)(F)F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F10 compound treatment 1325566.0 529000.0 1.12 968796.0 251000.0 0.57 1.1955 0.9508 3024371 ChemDiv3_004344 Cc1cc(C)nc(SCc2nnc(SC/C=C/c3ccccc3)o2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F11 compound treatment 1244449.0 448000.0 0.95 1133436.0 415000.0 0.94 1.3386 1.0 3117767 ChemDiv3_004345 CCOc1ccc(NC(=N)Nc2nc(cc(n2)C(F)(F)F)C(F)(F)F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F12 compound treatment 1391508.0 595000.0 1.26 1233591.0 515000.0 1.17 1.72 0.9993 3024372 ChemDiv3_004346 CCOC(=O)Cc1csc(n1)/C(=N/O)/C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F13 compound treatment 1466100.0 669000.0 1.42 1061686.0 344000.0 0.78 1.5555 0.9605 3117768 ChemDiv3_004347 COC(=O)c1c(F)c(F)c(Oc2ccc(Cl)cc2)c(F)c1N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F14 compound treatment 1376738.0 580000.0 1.23 1038946.0 321000.0 0.73 1.385 0.969 1296118 ChemDiv3_004348 CC(Nc1nc2nonc2nc1NC(C)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F15 compound treatment 1211023.0 414000.0 0.88 1256642.0 539000.0 1.22 1.4865 0.9867 3024373 ChemDiv3_004349 Clc1ccccc1C(=O)Oc2ccccc2/C=C\3/N=C4CCCCCN4C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F16 compound treatment 1348772.0 552000.0 1.17 1050426.0 332000.0 0.76 1.3615 0.9776 3117910 ChemDiv3_004350 O=C/1ON=C(\C1=C/c2ccc3OCOc3c2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F17 compound treatment 1267555.0 471000.0 1.0 1085704.0 368000.0 0.84 1.2965 0.9961 1675128 ChemDiv3_004351 CC1=C(C(c2ccncc2)n3ncnc3N1)C(=O)Nc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F18 compound treatment 1216390.0 419000.0 0.89 1403231.0 685000.0 1.56 1.7303 0.9647 3117911 ChemDiv3_004352 COc1cc(/C=C/2\C(=NOC2=O)C)cc(Cl)c1OCc3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F19 compound treatment 1171469.0 375000.0 0.79 1243746.0 526000.0 1.2 1.4065 0.9803 3117912 ChemDiv3_004353 CC(C)CNS(=O)(=O)c1ccccc1C(=O)N2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F20 compound treatment 1376159.0 579000.0 1.23 1090929.0 373000.0 0.85 1.4677 0.9836 3024374 ChemDiv3_004354 S=C(NCCC1=CCCCC1)Nc2ccc3nsnc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F21 compound treatment 1292655.0 496000.0 1.05 1207903.0 490000.0 1.11 1.5306 0.9996 1516017 ChemDiv3_004355 Clc1ccc(CN2C(=O)c3ccccc3S2(=O)=O)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F22 compound treatment 1199173.0 402000.0 0.85 1144461.0 426000.0 0.97 1.2884 0.998 3024375 ChemDiv3_004356 C(Sc1nnc(o1)c2cccnc2)/C=C/c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F23 mock treatment 1214965.0 418000.0 0.89 1012500.0 294000.0 0.67 1.1 0.9904 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 F24 mock treatment 799861.0 2940.0 0.01 458889.0 -259000.0 -0.59 -0.4123 -0.6996 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G01 compound treatment 741746.0 -55200.0 -0.12 560160.0 -158000.0 -0.36 -0.3366 -0.8913 1561444 ChemDiv3_004357 COC(=O)C1=C(C)NC2=C(C1c3ccc(OC)cc3)C(=O)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G02 compound treatment 1146993.0 350000.0 0.74 907472.0 189000.0 0.43 0.8292 0.9665 3024376 ChemDiv3_004358 Cc1ccc2cc(C3CC(=NN3S(=O)(=O)C)c4ccco4)c(=O)[nH]c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G03 compound treatment 970583.0 174000.0 0.37 924166.0 206000.0 0.47 0.5916 0.9929 3117913 ChemDiv3_004359 COc1ccccc1NC(=O)C(NC(=O)c2ccccc2NC(=O)c3ccccc3)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G04 compound treatment 963486.0 167000.0 0.35 933097.0 215000.0 0.49 0.5953 0.9873 1365443 ChemDiv3_004360 Cc1ccc(cc1)S(=O)(=O)NCC(O)Cn2c3ccccc3c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G05 compound treatment 806895.0 9980.0 0.02 720909.0 2810.0 0.01 0.0195 0.8814 1229059 ChemDiv3_004361 CCOC(=O)c1cn(CC)c2cc(F)c(F)cc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G06 compound treatment 1305525.0 509000.0 1.08 1080113.0 362000.0 0.82 1.3444 0.9911 3117914 ChemDiv3_004362 CC(=O)N1CN(Cc2ccccc2)Cc3c4CCCCc4sc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G07 compound treatment 1425178.0 628000.0 1.33 1273043.0 555000.0 1.26 1.8339 0.9996 3024377 ChemDiv3_004363 Clc1ccc(Sc2c(nc3ncccn23)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G08 compound treatment 567308.0 -230000.0 -0.49 478542.0 -240000.0 -0.54 -0.7293 -0.9984 3117915 ChemDiv3_004364 CCCc1cc(N2CCN(CC2)c3ccccc3)n4c5ccccc5nc4c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G09 compound treatment 1258642.0 462000.0 0.98 1220143.0 502000.0 1.14 1.4992 0.9971 3024378 ChemDiv3_004365 COc1ccc(NC(=O)CSc2nc(O)cc(=O)[nH]2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G10 compound treatment 1438231.0 641000.0 1.36 1194802.0 477000.0 1.08 1.7277 0.9937 3024435 ChemDiv3_004366 Clc1ccc(Cn2cccc2/C=C\3/C(=N)N4C=CSC4=NC3=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G11 compound treatment 1282558.0 486000.0 1.03 1400286.0 682000.0 1.55 1.8247 0.9802 1393315 ChemDiv3_004367 COc1ccc(NC(=O)N2c3ccccc3Sc4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G12 compound treatment 1402605.0 606000.0 1.28 1093713.0 376000.0 0.85 1.5118 0.9804 3024436 ChemDiv3_004368 N(=c/1\oc2ccccc2cc1c3nc4ccccc4[nH]3)\c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G13 compound treatment 1564844.0 768000.0 1.63 1264257.0 546000.0 1.24 2.0292 0.9911 3024437 ChemDiv3_004369 CCC1(C)Cc2nc3nc(SCC(=O)c4ccccc4)n(Cc5ccccc5)c(=O)c3cc2CO1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G14 compound treatment 1370614.0 574000.0 1.22 1255401.0 537000.0 1.22 1.7238 1.0 3024438 ChemDiv3_004370 Cc1cc(C(=O)OCCN2CCN(CC2)C3=NS(=O)(=O)c4ccccc34)c5ccccc5n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G15 compound treatment 1115815.0 319000.0 0.68 1292872.0 575000.0 1.31 1.4021 0.9529 1264788 ChemDiv3_004371 COc1ccc(cc1)C2C3C(ON2c4ccc(Cl)cc4)C(=O)N(C(C)C)C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G16 compound treatment 1172515.0 376000.0 0.8 1276468.0 558000.0 1.27 1.4607 0.9747 3117916 ChemDiv3_004372 CCCCC1(C)OC(=O)C(=Cc2ccc(F)cc2)C(=O)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G17 compound treatment 154071.0 -643000.0 -1.36 100387.0 -618000.0 -1.4 -1.9567 -0.9999 1307836 ChemDiv3_004373 CCCCN1COc2ccc3c4C(=O)c5ccccc5C(=O)c4oc3c2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G18 compound treatment 689965.0 -107000.0 -0.23 730067.0 12000.0 0.03 -0.1411 -0.6178 1527245 ChemDiv3_004374 CP(=O)(Nc1ccc(Cl)cc1)Oc2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G19 compound treatment 732547.0 -64400.0 -0.14 742609.0 24500.0 0.06 -0.0571 -0.3873 1557708 ChemDiv3_004375 CCN(CC)CCNc1nc2n(C)c(=O)n(C)c(=O)c2n1C(C)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G20 compound treatment 1106848.0 310000.0 0.66 1323681.0 606000.0 1.38 1.4382 0.9427 1285083 ChemDiv3_004376 NS(=O)(=O)c1ccc(NC(=O)CCCC(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G21 compound treatment 1013647.0 217000.0 0.46 1223472.0 505000.0 1.15 1.1373 0.9191 3117917 ChemDiv3_004377 Cc1ccc(NC(=O)CC(NCCN2CCOCC2)C(=O)O)cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G22 compound treatment 876507.0 79600.0 0.17 1142234.0 424000.0 0.96 0.8012 0.8184 1782201 ChemDiv3_004378 N#CSCc1nc2ccccc2c3nc4ccccc4n13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G23 mock treatment 800936.0 4020.0 0.01 1133291.0 415000.0 0.94 0.6735 0.7135 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 G24 mock treatment 640312.0 -157000.0 -0.33 600775.0 -117000.0 -0.27 -0.4234 -0.9941 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H01 compound treatment 516728.0 -280000.0 -0.59 665240.0 -52900.0 -0.12 -0.505 -0.8333 3117918 ChemDiv3_004379 CCOC(=O)C1=C(C)N=C(NC1c2ccc(OCC)cc2)SCc3ccc(cc3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H02 compound treatment 805036.0 8120.0 0.02 926074.0 208000.0 0.47 0.3465 0.7324 3024439 ChemDiv3_004380 CCOC(=O)/C(=C\1/C=CN(C)C=N1)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H03 compound treatment 1231167.0 434000.0 0.92 1230909.0 513000.0 1.17 1.4754 0.9932 3117919 ChemDiv3_004381 Cc1ccc2nc3n(Cc4cccnc4)c(=N)c(cc3c(=O)n2c1)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H04 compound treatment 655645.0 -141000.0 -0.3 620694.0 -97400.0 -0.22 -0.3684 -0.989 3024440 ChemDiv3_004382 NC(=O)COc1cccc(/C=C/2\CC/C(=C/c3cccc(OCC(=O)N)c3)/C2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H05 compound treatment 1136331.0 339000.0 0.72 1261470.0 543000.0 1.24 1.3823 0.9669 3117920 ChemDiv3_004383 N=c1c(C#N)cc2c(=O)n3ccccc3nc2n1C4CCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H06 compound treatment 296512.0 -500000.0 -1.06 276129.0 -442000.0 -1.0 -1.4607 -0.9996 1915671 ChemDiv3_004384 N1C(=CC(c2ccccc2)n3c1nc4ccccc34)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H07 compound treatment 810732.0 13800.0 0.03 812082.0 94000.0 0.21 0.1718 0.7966 3024441 ChemDiv3_004385 CC1(C)OC(=O)C=C(O1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H08 compound treatment 975597.0 179000.0 0.38 1059011.0 341000.0 0.78 0.8159 0.9458 1820724 ChemDiv3_004386 Nc1cc(N)nc(SCC(=O)N2c3ccccc3Sc4ccccc24)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H09 compound treatment 1469910.0 673000.0 1.43 896840.0 179000.0 0.41 1.2962 0.8738 3117921 ChemDiv3_004387 CN(C)c1ccc(NC(=N)Nc2nc(cc(n2)C(F)(F)F)C(F)(F)F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H10 compound treatment 1323610.0 527000.0 1.12 1466239.0 748000.0 1.7 1.9923 0.9792 3024442 ChemDiv3_004388 Cc1cc(C)nc(SCc2nnc(SCC(=O)NCc3ccccc3)o2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H11 compound treatment 780572.0 -16300.0 -0.03 830682.0 113000.0 0.26 0.1565 0.6059 3117922 ChemDiv3_004389 Cc1ccccc1NC2=NC(=NC3(CCCCC3)N2)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H12 compound treatment 1540295.0 743000.0 1.58 1435427.0 717000.0 1.63 2.2676 0.9999 1869886 ChemDiv3_004390 CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(=O)CCN2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H13 compound treatment 1697183.0 900000.0 1.91 1114319.0 396000.0 0.9 1.9865 0.9413 3117923 ChemDiv3_004391 Cc1onc(c1C(=O)NC(=S)NC2CCSC2=O)c3c(F)cccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H14 compound treatment 1067206.0 270000.0 0.57 933165.0 215000.0 0.49 0.7509 0.9969 1513000 ChemDiv3_004392 O=c1nc(Nc2ccc3ccccc3c2)nc([nH]1)N4CCOCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H15 compound treatment 1299690.0 503000.0 1.07 1283129.0 565000.0 1.28 1.662 0.9957 1396416 ChemDiv3_004393 Cc1cc(NC(=O)CSc2ccc(C)cc2)no1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H16 compound treatment 1103271.0 306000.0 0.65 1137458.0 419000.0 0.95 1.1334 0.9825 3117924 ChemDiv3_004394 Cc1cc(Cl)ccc1NS(=O)(=O)c2ccc3N[C@@H]([C@@H]4CC=C[C@@H]4c3c2)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H17 compound treatment 1016226.0 219000.0 0.46 999383.0 281000.0 0.64 0.781 0.9877 3024443 ChemDiv3_004395 CC/1=CC(=O)C=C\C1=N\C(=N/S(=O)(=O)c2ccc(C)cc2)\c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H18 compound treatment 1428889.0 632000.0 1.34 1294365.0 576000.0 1.31 1.8738 0.9999 3117925 ChemDiv3_004396 CCOc1cc(/C=C/2\C(=NOC2=O)C)cc(Cl)c1OCc3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H19 compound treatment 1341281.0 544000.0 1.15 1298078.0 580000.0 1.32 1.7484 0.9978 3024444 ChemDiv3_004397 O=C(N1CCCC1)c2ccccc2S(=O)(=O)NCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H20 compound treatment 1201496.0 405000.0 0.86 999633.0 282000.0 0.64 1.0591 0.9896 3117926 ChemDiv3_004398 C=CCn1cc(/C=C\2/NC(=O)N(C2=O)c3ccccc3)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H21 compound treatment 767740.0 -29200.0 -0.06 691856.0 -26200.0 -0.06 -0.0859 -0.9998 3024445 ChemDiv3_004399 CCOc1ccc(cc1)C2=NCCNC3=C2C(N(C3=O)c4ccccc4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H22 compound treatment 1102493.0 306000.0 0.65 942204.0 224000.0 0.51 0.8184 0.9929 1672517 ChemDiv3_004400 O=C(Cc1c[nH]c2ccccc12)NCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H23 mock treatment 1036473.0 240000.0 0.51 1017494.0 299000.0 0.68 0.8404 0.9896 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 H24 mock treatment 657221.0 -140000.0 -0.3 628420.0 -89700.0 -0.2 -0.3536 -0.9834 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I01 compound treatment 784341.0 -12600.0 -0.03 688212.0 -29900.0 -0.07 -0.0669 -0.9165 3117927 ChemDiv3_004401 CCC1(CN2CC3(CC)CN(C1)C(=O)c4ccccc4C2=O)C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I02 compound treatment 1375515.0 579000.0 1.23 1159151.0 441000.0 1.0 1.5764 0.995 3024446 ChemDiv3_004402 FC(F)(F)C1(NC(=O)N2CCCN=C2S1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I03 compound treatment 1310371.0 513000.0 1.09 1116673.0 399000.0 0.91 1.4105 0.9958 3117928 ChemDiv3_004403 Cc1csc(/C=C/2\CCc3c(cnc4ccc5ccccc5c34)C2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I04 compound treatment 1185413.0 388000.0 0.82 1166809.0 449000.0 1.02 1.3037 0.9944 3024447 ChemDiv3_004404 Cc1cc2nnc(SCc3ccc(Cl)cc3)n2c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I05 compound treatment 1347591.0 551000.0 1.17 1030409.0 312000.0 0.71 1.3276 0.9716 1803276 ChemDiv3_004405 CCC(Sc1nc2CCCCCc2cc1C#N)C(=O)Nc3cc(C)on3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I06 compound treatment 1034008.0 237000.0 0.5 853160.0 135000.0 0.31 0.5725 0.9721 3118072 ChemDiv3_004406 CC(=O)Nc1sc2CCCCc2c1CN3CCN(CC3)c4ccccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I07 compound treatment 1640866.0 844000.0 1.79 1219542.0 501000.0 1.14 2.0713 0.9763 3024448 ChemDiv3_004407 FC(F)(F)c1cc(nc2c(cnn12)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I08 compound treatment 1105378.0 308000.0 0.65 1123729.0 406000.0 0.92 1.1145 0.9858 3118073 ChemDiv3_004408 CCCc1cc(NC(C)c2ccccc2)n3c4ccccc4nc3c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I09 compound treatment 1825939.0 1030000.0 2.18 1320260.0 602000.0 1.37 2.5106 0.9748 3024449 ChemDiv3_004409 Cc1cc(C)c(c(C)c1)S(=O)(=O)/N=C/2\SCCN2S(=O)(=O)c3c(C)cc(C)cc3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I10 compound treatment 1849455.0 1050000.0 2.23 1541771.0 824000.0 1.87 2.902 0.9962 3118074 ChemDiv3_004410 CCCc1nn(c(O)c1/C(=N/c2ccc(cc2)C(=O)OCC)/C)c3nc4ccccc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I11 compound treatment 1612858.0 816000.0 1.73 1174436.0 456000.0 1.04 1.9568 0.9701 1190406 ChemDiv3_004411 CC(C)CNC(=O)N1c2ccccc2Sc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I12 compound treatment 1874310.0 1080000.0 2.28 1964386.0 1250000.0 2.83 3.6186 0.9943 3118075 ChemDiv3_004412 COc1cc(=O)n(C)c2cc(ccc12)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I13 compound treatment 1926912.0 1130000.0 2.4 1253430.0 535000.0 1.22 2.5545 0.9507 3024450 ChemDiv3_004413 CSc1nc(C)cc(OCCO)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I14 compound treatment 1873808.0 1080000.0 2.28 1386411.0 668000.0 1.52 2.6887 0.9804 3118076 ChemDiv3_004414 Clc1cc(/C=C\2/C(=N)N3C=CSC3=NC2=O)ccc1OCCOc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I15 compound treatment 1138060.0 341000.0 0.72 1323900.0 606000.0 1.38 1.4853 0.9548 1567868 ChemDiv3_004415 Cc1ccc2[nH]c(SCc3nc4cccc(C)n4c3Br)nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I16 compound treatment 1133912.0 337000.0 0.71 1418960.0 701000.0 1.59 1.6319 0.9345 3118077 ChemDiv3_004416 CCOC(=O)N1C(=O)c2ccccc2NC1(C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I17 compound treatment 1512022.0 715000.0 1.52 1308138.0 590000.0 1.34 2.0205 0.9981 1709676 ChemDiv3_004417 O=C1N(CN2CCc3ccccc3C2)c4cccc5cccc1c45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I18 compound treatment 1681672.0 885000.0 1.88 1139807.0 422000.0 0.96 2.0042 0.9515 3024451 ChemDiv3_004418 Cc1onc(c1C(=O)OC(c2ccccc2)C(F)(F)F)c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I19 compound treatment 1669334.0 872000.0 1.85 1444499.0 726000.0 1.65 2.4756 0.9984 3118078 ChemDiv3_004419 Cc1ccc2sc(nc2c1)c3nc4ccccc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I20 compound treatment 1447276.0 650000.0 1.38 1126612.0 409000.0 0.93 1.6317 0.9815 3024452 ChemDiv3_004420 CCCCn1c2ccccc2c3nc4ccccc4nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I21 compound treatment 199765.0 -597000.0 -1.27 130010.0 -588000.0 -1.34 -1.8406 -0.9996 1873833 ChemDiv3_004421 Cc1cccc(NC2=C(C(=O)c3ccccc3C2=O)n4nnc5ccccc45)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I22 compound treatment 1386544.0 590000.0 1.25 1180410.0 462000.0 1.05 1.6271 0.9963 3024453 ChemDiv3_004422 COc1nc(c2ccccc2Cl)c3cc(Br)ccc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I23 mock treatment 1141948.0 345000.0 0.73 1175230.0 457000.0 1.04 1.2521 0.9852 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 I24 mock treatment 551183.0 -246000.0 -0.52 838247.0 120000.0 0.27 -0.1752 -0.2979 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J01 compound treatment 541633.0 -255000.0 -0.54 655922.0 -62200.0 -0.14 -0.4826 -0.8629 3118079 ChemDiv3_004423 CN(C)c1ccc(cc1)C2NC(=S)NC(=C2C(=O)Nc3cc(C)ccc3C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J02 compound treatment 822581.0 25700.0 0.05 1005958.0 288000.0 0.65 0.5012 0.7633 3024454 ChemDiv3_004424 C[N+]1(CCn2ccc3ccccc23)CCCCC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J03 compound treatment 1612366.0 815000.0 1.73 1526845.0 809000.0 1.84 2.5226 0.9995 3118080 ChemDiv3_004425 N=c1c(cc2c(=O)n3ccccc3nc2n1Cc4cccnc4)C(=O)NC5CCCCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J04 compound treatment 871692.0 74800.0 0.16 1036240.0 318000.0 0.72 0.6235 0.8421 3118081 ChemDiv3_004426 CCOC(=O)C1=C(OC(=C(C#N)C1c2cccnc2)N)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J05 compound treatment 882507.0 85600.0 0.18 992865.0 275000.0 0.62 0.57 0.8763 3024455 ChemDiv3_004427 COC(=O)C/1=C(C)N(C(C)C)C(=O)\C1=C/c2ccc(cc2)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J06 compound treatment 1492326.0 695000.0 1.47 1489273.0 771000.0 1.75 2.2822 0.9963 1162906 ChemDiv3_004428 COc1cc2c(cc1NC(=O)c3ccccc3)oc4ccccc42 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J07 compound treatment 620845.0 -176000.0 -0.37 727281.0 9180.0 0.02 -0.2492 -0.6665 3024456 ChemDiv3_004429 COc1ccc(cc1)C2=CC(=O)OC3(CCCCC3)O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J08 compound treatment 914655.0 118000.0 0.25 1162903.0 445000.0 1.01 0.8916 0.8559 3118082 ChemDiv3_004430 COc1ccccc1n2c(C)nc(=O)c(c2C)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J09 compound treatment 260698.0 -536000.0 -1.14 299770.0 -418000.0 -0.95 -1.4763 -0.9961 3024457 ChemDiv3_004431 Cc1cccc(c1)N2C(=NC(=NC32CCCCC3)N)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J10 compound treatment 1523555.0 727000.0 1.54 1594977.0 877000.0 1.99 2.499 0.9919 1868948 ChemDiv3_004432 CCSc1nc2OC(=C(C#N)C(C(C)C)c2c(=O)[nH]1)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J11 compound treatment 706627.0 -90300.0 -0.19 726731.0 8630.0 0.02 -0.1215 -0.6313 3118083 ChemDiv3_004433 CCOC(=O)c1cccc(NC2=NC(=NC3(CCCCC3)N2)N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J12 compound treatment 1875764.0 1080000.0 2.29 1737144.0 1020000.0 2.32 3.2555 1.0 3024458 ChemDiv3_004434 CC(=O)OC(C(=O)Nc1nc2ccccc2s1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J13 compound treatment 1145282.0 348000.0 0.74 1555409.0 837000.0 1.9 1.8683 0.915 3118084 ChemDiv3_004435 Cc1nn(c2ccccc2)c3sc(cc13)C(=O)NC(=S)NC4CCSC4=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J14 compound treatment 1195628.0 399000.0 0.85 1110644.0 393000.0 0.89 1.2288 0.9996 3024459 ChemDiv3_004436 CCOC(=O)CC1(C)NNC(=S)NN1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J15 compound treatment 1484348.0 687000.0 1.46 1388020.0 670000.0 1.52 2.1075 0.9998 1554274 ChemDiv3_004437 COc1ccc(cc1)C2=NN(C(C2)c3cccc(OC)c3OC)C(=O)CSCc4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J16 compound treatment 1664296.0 867000.0 1.84 1483468.0 765000.0 1.74 2.5307 0.9996 3024460 ChemDiv3_004438 COc1cccc([C@H]2Nc3ccc(cc3[C@H]4C=CC[C@H]42)S(=O)(=O)Nc5ccc(C)c(C)c5)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J17 compound treatment 1615413.0 818000.0 1.74 1331945.0 614000.0 1.4 2.2138 0.9942 1189392 ChemDiv3_004439 COc1ccc(cc1OC)C(O)c2cccs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J18 compound treatment 1646508.0 850000.0 1.8 1369518.0 651000.0 1.48 2.3208 0.9953 3118085 ChemDiv3_004440 Cc1ccc(cc1)c2ccc(CCC(=O)O)n2c3cc(C)cc(C)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J19 compound treatment 1389125.0 592000.0 1.26 1254090.0 536000.0 1.22 1.7494 0.9999 3024461 ChemDiv3_004441 CCn1cnc2cc(NS(=O)(=O)c3ccc(C)cc3)ccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J20 compound treatment 1097085.0 300000.0 0.64 941550.0 223000.0 0.51 0.8092 0.9938 1913074 ChemDiv3_004442 CC(C)C/C(=N\O)/c1cn(C)c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J21 compound treatment 1250215.0 453000.0 0.96 970611.0 253000.0 0.57 1.0855 0.9697 3118086 ChemDiv3_004443 OC1=C(C(OC1=O)c2ccc(Cl)cc2)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J22 compound treatment 1318471.0 522000.0 1.11 1136899.0 419000.0 0.95 1.4551 0.9972 1565919 ChemDiv3_004444 Cc1oc2c(C)c3oc(=O)c4CCCCc4c3cc2c1c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J23 mock treatment 1110470.0 314000.0 0.66 1007826.0 290000.0 0.66 0.9358 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 J24 mock treatment 675818.0 -121000.0 -0.26 512755.0 -205000.0 -0.47 -0.5117 -0.9603 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K01 compound treatment 620486.0 -176000.0 -0.37 677012.0 -41100.0 -0.09 -0.3305 -0.8574 3024519 ChemDiv3_004445 CCNc1nc(NC(C)C)nc(Oc2ccc(/C=N/O)cc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K02 compound treatment 966594.0 170000.0 0.36 955547.0 237000.0 0.54 0.6361 0.9805 3024520 ChemDiv3_004446 COc1ccc2N3C(=NC(NC3=O)(c4ccccc4)C(F)(F)F)Sc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K03 compound treatment 1119020.0 322000.0 0.68 1078170.0 360000.0 0.82 1.0617 0.9959 3024521 ChemDiv3_004447 COC(=O)CCC(=O)C1=C(CC(C)(C)CC1=O)NCC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K04 compound treatment 1107533.0 311000.0 0.66 1067907.0 350000.0 0.8 1.028 0.9956 3024522 ChemDiv3_004448 Cc1nn(c(O)c1Sc2ccc(Cl)cc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K05 compound treatment 1123155.0 326000.0 0.69 1008860.0 291000.0 0.66 0.9565 0.9997 1868645 ChemDiv3_004449 CCc1ccc(cc1)c2csc(Nc3ccc(cc3)S(=O)(=O)Nc4cc(OC)nc(OC)n4)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K06 compound treatment 189999.0 -607000.0 -1.29 188023.0 -530000.0 -1.21 -1.762 -0.9995 3024523 ChemDiv3_004450 Cc1sc(NC(=O)c2ccco2)c(C(N3CCCC3)c4cccnc4)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K07 compound treatment 1404092.0 607000.0 1.29 1533698.0 816000.0 1.85 2.2214 0.9841 3118087 ChemDiv3_004451 COC(=O)C1=CN(CCc2ccc(F)cc2)C=C(C1c3ccccc3C(F)(F)F)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K08 compound treatment 1367506.0 571000.0 1.21 1498583.0 780000.0 1.77 2.1101 0.9826 1873196 ChemDiv3_004452 CC(C)c1cc(NC2CCCCC2)n3c4ccccc4nc3c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K09 compound treatment 1098649.0 302000.0 0.64 1096232.0 378000.0 0.86 1.0602 0.9894 3118088 ChemDiv3_004453 CC1=CCC(COC(=O)Nc2ccccc2)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K10 compound treatment 1325826.0 529000.0 1.12 1315724.0 598000.0 1.36 1.7536 0.9954 1871904 ChemDiv3_004454 COC(=O)CSc1c(c2ccccc2)c3cc(Cl)ccc3[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K11 compound treatment 1199224.0 402000.0 0.85 1251990.0 534000.0 1.21 1.4614 0.9851 1712836 ChemDiv3_004455 CCC(C)NC(=O)N1c2ccccc2Sc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K12 compound treatment 1109336.0 312000.0 0.66 1023400.0 305000.0 0.69 0.9591 0.9997 1183223 ChemDiv3_004456 O=C(CNC(=O)C1CCCCC1)Nc2nc(CC3(CC4CC5CC(C4)C3)C5)cs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K13 compound treatment 602994.0 -194000.0 -0.41 571422.0 -147000.0 -0.33 -0.5265 -0.9946 3024524 ChemDiv3_004457 CC(C)Oc1ccc(CNCCC(c2ccco2)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K14 compound treatment 1332330.0 535000.0 1.14 1261900.0 544000.0 1.24 1.6768 0.9991 3118089 ChemDiv3_004458 Cc1ccc(COc2ccc(/C=C\3/C(=N)N4C=CSC4=NC3=O)cc2Br)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K15 compound treatment 1333030.0 536000.0 1.14 1274109.0 556000.0 1.26 1.6975 0.9986 1204806 ChemDiv3_004459 Cc1nn(c2ccccc2)c3sc(cc13)C(=O)OCN4C(=O)c5ccccc5C4=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K16 compound treatment 1166949.0 370000.0 0.78 1371575.0 653000.0 1.49 1.6052 0.9555 3118090 ChemDiv3_004460 NC1=C(C#N)C(C2=C(CCC2)N1c3ccc(cc3)S(=O)(=O)N)(C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K17 compound treatment 1258121.0 461000.0 0.98 1335817.0 618000.0 1.4 1.6844 0.9843 1453567 ChemDiv3_004461 CCSc1nc2NC(=C(C(c3ccncc3)c2c(=O)[nH]1)C(=O)OC)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K18 compound treatment 1252090.0 455000.0 0.96 1363630.0 646000.0 1.47 1.7201 0.9793 1234228 ChemDiv3_004462 CC1CN(CC(C)O1)C(=O)NC(C)(C)c2cccc(c2)C(=C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K19 compound treatment 1184821.0 388000.0 0.82 1260024.0 542000.0 1.23 1.4527 0.9807 1601073 ChemDiv3_004463 CCc1ccc(cc1)S(=O)(=O)Nc2ccc3oc(=O)sc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K20 compound treatment 1206886.0 410000.0 0.87 1216373.0 498000.0 1.13 1.4156 0.9914 1200402 ChemDiv3_004464 CCOC(=O)Cc1c(c2ccccc2)c3cc(Cl)ccc3[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K21 compound treatment 1142503.0 346000.0 0.73 1071907.0 354000.0 0.8 1.0868 0.9989 1869882 ChemDiv3_004465 CCOc1ccc2n(CO)c(=S)n(CO)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K22 compound treatment 1145669.0 349000.0 0.74 1149421.0 431000.0 0.98 1.2162 0.9903 3024525 ChemDiv3_004466 Cc1cccc(OCC(=O)OC2CN3CCC2CC3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K23 mock treatment 859964.0 63000.0 0.13 920134.0 202000.0 0.46 0.4193 0.8765 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 K24 mock treatment 488516.0 -308000.0 -0.65 541092.0 -177000.0 -0.4 -0.7469 -0.9728 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L01 compound treatment 545059.0 -252000.0 -0.53 699023.0 -19100.0 -0.04 -0.4082 -0.762 1875198 ChemDiv3_004467 CCOC(=O)c1cc2c(=O)n3cc(C)ccc3nc2n(Cc4ccco4)c1=N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L02 compound treatment 1198505.0 402000.0 0.85 1189343.0 471000.0 1.07 1.3596 0.9935 3024526 ChemDiv3_004468 CC(N)Cc1c[nH]c2ccc(C)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L03 compound treatment 1360082.0 563000.0 1.19 1374486.0 656000.0 1.49 1.8994 0.9939 3118218 ChemDiv3_004469 CN1CCN(CC1)C(=O)c2cc3c(=O)n4cccc(C)c4nc3n(Cc5cccnc5)c2=N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L04 compound treatment 1115398.0 318000.0 0.68 1323240.0 605000.0 1.38 1.4503 0.9463 3118219 ChemDiv3_004470 CN1CCc2nc(SCC(=O)Nc3ccccc3OC(F)(F)F)c(C#N)cc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L05 compound treatment 1095807.0 299000.0 0.63 1144965.0 427000.0 0.97 1.1343 0.9787 3024527 ChemDiv3_004471 COC(=O)C/1=C(C)N(C(C)c2ccccc2)C(=O)\C1=C/c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L06 compound treatment 1504853.0 708000.0 1.5 1160002.0 442000.0 1.0 1.7716 0.981 1604904 ChemDiv3_004472 COC(=O)c1cn(C(=O)c2ccccc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L07 compound treatment 954217.0 157000.0 0.33 818882.0 101000.0 0.23 0.3978 0.9832 1406130 ChemDiv3_004473 COc1ccc(cc1)C2=CC(=O)N(C(O2)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L08 compound treatment 1103240.0 306000.0 0.65 1143564.0 425000.0 0.97 1.1432 0.9812 1691728 ChemDiv3_004474 C(c1nc2ccc3nsnc3c2[nH]1)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L09 compound treatment 637449.0 -159000.0 -0.34 606981.0 -111000.0 -0.25 -0.4177 -0.9897 3118220 ChemDiv3_004475 COc1ccccc1N2C(=NC(=NC32CCCCC3)N)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L10 compound treatment 1344878.0 548000.0 1.16 1168108.0 450000.0 1.02 1.5449 0.998 3024528 ChemDiv3_004476 CN(C)c1nc(c2ccccc2)[n+](C)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L11 compound treatment 358933.0 -438000.0 -0.93 325335.0 -393000.0 -0.89 -1.288 -0.9998 3118221 ChemDiv3_004477 COc1cccc(NC2=NC3(CCCC3)NC(=N2)N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L12 compound treatment 1965167.0 1170000.0 2.48 1602286.0 884000.0 2.01 3.1727 0.9946 3024529 ChemDiv3_004478 COC(=O)CSc1nnc2sc3ccccc3n12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L13 compound treatment 1939820.0 1140000.0 2.42 1283326.0 565000.0 1.29 2.6219 0.956 1151035 ChemDiv3_004479 COc1ccc(CCNC(=O)CSc2nc(C)cc(C)n2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L14 compound treatment 1860830.0 1060000.0 2.26 1696599.0 979000.0 2.22 3.1679 1.0 3024530 ChemDiv3_004480 COC(=O)c1ccc2nsnc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L15 compound treatment 1776601.0 980000.0 2.08 1215170.0 497000.0 1.13 2.2677 0.9591 3118222 ChemDiv3_004481 COc1ccc(cc1)C2CC(=NN2C(=O)CSc3nc4ccccc4s3)c5cccs5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L16 compound treatment 1436672.0 640000.0 1.36 1328378.0 610000.0 1.39 1.9401 0.9999 3024531 ChemDiv3_004482 CCOC(=O)[C@@H]1Nc2ccc(cc2[C@@H]3C=CC[C@@H]31)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L17 compound treatment 1658030.0 861000.0 1.83 1325221.0 607000.0 1.38 2.2669 0.9905 3118223 ChemDiv3_004483 Cc1c(c2ccccc2)c3cc(C)cc4CCCn1c43 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L18 compound treatment 1464061.0 667000.0 1.41 1341978.0 624000.0 1.42 2.003 1.0 3024532 ChemDiv3_004484 OC(=O)CCc1ccc(c2cccs2)n1c3ccccc3C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L19 compound treatment 123443.0 -673000.0 -1.43 106624.0 -611000.0 -1.39 -1.9926 -0.9999 3118224 ChemDiv3_004485 CCCCn1c(=N)n(CC(O)COc2ccc(OC)cc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L20 compound treatment 1289207.0 492000.0 1.04 1001927.0 284000.0 0.65 1.1943 0.9733 3024533 ChemDiv3_004486 C(Sc1nc2ccccc2n1Cc3ccccn3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L21 compound treatment 1591658.0 795000.0 1.68 1055290.0 337000.0 0.77 1.7334 0.9365 3118225 ChemDiv3_004487 Brc1ccc(cc1)C(=O)/C=C\2/NCCNC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L22 compound treatment 1487161.0 690000.0 1.46 1115556.0 397000.0 0.9 1.6737 0.9732 1635205 ChemDiv3_004488 CCCc1cc(=O)oc2cc3occ(c4ccccc4)c3cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L23 mock treatment 1154396.0 357000.0 0.76 719274.0 1180.0 0.0 0.5378 0.7096 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 L24 mock treatment 607187.0 -190000.0 -0.4 480122.0 -238000.0 -0.54 -0.667 -0.9893 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M01 compound treatment 677963.0 -119000.0 -0.25 542720.0 -175000.0 -0.4 -0.4603 -0.9756 3024534 ChemDiv3_004489 COc1nc(Oc2ccc(/C=N/O)cc2)nc(n1)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M02 compound treatment 1104599.0 308000.0 0.65 883651.0 166000.0 0.38 0.7274 0.9659 3118226 ChemDiv3_004490 O=C(Oc1nsnc1N2CCCCC2)N(c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M03 compound treatment 1349733.0 553000.0 1.17 1008805.0 291000.0 0.66 1.296 0.9633 3024535 ChemDiv3_004491 CCOC(=O)Nc1nc2ccc(C)cc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M04 compound treatment 834223.0 37300.0 0.08 703559.0 -14500.0 -0.03 0.0325 0.3797 3118227 ChemDiv3_004492 Cc1nn(c(O)c1Sc2ccc(C)cc2)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M05 compound treatment 1309717.0 513000.0 1.09 1035479.0 317000.0 0.72 1.2789 0.9802 1868767 ChemDiv3_004493 COc1ccc(cc1C)c2csc(Nc3ccc(cc3)S(=O)(=O)Nc4cc(C)on4)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M06 compound treatment 1438885.0 642000.0 1.36 1273509.0 555000.0 1.26 1.8552 0.9993 3024536 ChemDiv3_004494 O=C1CC(SC(=N1)N(c2ccccc2)c3ccccc3)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M07 compound treatment 1513643.0 717000.0 1.52 1531661.0 814000.0 1.85 2.3823 0.9952 3118228 ChemDiv3_004495 COC(=O)C1=CN(Cc2cccs2)C=C(C1c3cccc(OC)c3)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M08 compound treatment 1450534.0 654000.0 1.39 1445107.0 727000.0 1.65 2.1486 0.9962 3024537 ChemDiv3_004496 CC(C)CCNc1cc(C(C)C)c(C#N)c2nc3ccccc3n12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M09 compound treatment 1171385.0 374000.0 0.79 930583.0 212000.0 0.48 0.9029 0.9716 3118229 ChemDiv3_004497 COC(=O)c1cc(c(Cl)cc1Cl)S(=O)(=O)/C=C/c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M10 compound treatment 1539842.0 743000.0 1.57 1102276.0 384000.0 0.87 1.7313 0.9613 3024538 ChemDiv3_004498 CCOC(=O)Cc1cc(O)n(n1)c2nc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M11 compound treatment 1147534.0 351000.0 0.74 921310.0 203000.0 0.46 0.8523 0.9738 1623227 ChemDiv3_004499 O=C(NCc1ccccc1)N2c3ccccc3Sc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M12 compound treatment 1409779.0 613000.0 1.3 1027640.0 310000.0 0.7 1.4163 0.9585 1497208 ChemDiv3_004500 O=C(CNC(=O)COc1ccccc1)Nc2nc(CC3(CC4CC5CC(C4)C3)C5)cs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M13 compound treatment 772142.0 -24800.0 -0.05 705908.0 -12200.0 -0.03 -0.0567 -0.9554 1480171 ChemDiv3_004501 C=CCSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1Cc5ccco5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M14 compound treatment 1217412.0 420000.0 0.89 1089173.0 371000.0 0.84 1.2269 0.9996 3024539 ChemDiv3_004502 CN(C)c1ccc(cc1)n2cccc2/C=N/n3cnnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M15 compound treatment 1061240.0 264000.0 0.56 978839.0 261000.0 0.59 0.8154 0.9996 1730629 ChemDiv3_004503 O=C(OCn1nnc2ccccc2c1=O)c3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M16 compound treatment 1180748.0 384000.0 0.81 1011775.0 294000.0 0.67 1.0475 0.9952 3118230 ChemDiv3_004504 FC(F)(F)C(NCc1ccccc1Cl)(NC(=O)c2ccccc2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M17 compound treatment 1024897.0 228000.0 0.48 1041769.0 324000.0 0.74 0.8621 0.9792 1482041 ChemDiv3_004505 CCc1ccc(cc1)C2C3=C(CCCC3=O)Nc4c2c(=O)n(C)c(=O)n4C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M18 compound treatment 989291.0 192000.0 0.41 1111579.0 393000.0 0.89 0.921 0.9367 1232456 ChemDiv3_004506 COc1ccccc1OCc2nc3ccccc3n2CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M19 compound treatment 1042616.0 246000.0 0.52 1191487.0 473000.0 1.08 1.1293 0.9445 3024540 ChemDiv3_004507 CC1=NN2C(=NNC2(C)c3ccccc3)NC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M20 compound treatment 792463.0 -4460.0 -0.01 848594.0 130000.0 0.3 0.2031 0.6843 3118231 ChemDiv3_004508 Clc1ccc2[nH]c(=O)c(c(c3ccccc3)c2c1)[n+]4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M21 compound treatment 1183545.0 387000.0 0.82 1133900.0 416000.0 0.95 1.248 0.9975 3118232 ChemDiv3_004509 Cc1cccc(C)c1NC2OC(=O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M22 compound treatment 1115409.0 318000.0 0.68 1147486.0 429000.0 0.98 1.1677 0.9838 3024541 ChemDiv3_004510 COC(=O)c1ccccc1Oc2c(F)c(F)nc(N3CCOCC3)c2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M23 mock treatment 890300.0 93400.0 0.2 1043453.0 325000.0 0.74 0.663 0.8659 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 M24 mock treatment 579839.0 -217000.0 -0.46 634943.0 -83200.0 -0.19 -0.4591 -0.9228 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N01 compound treatment 2542317.0 1750000.0 3.7 2539771.0 1820000.0 4.14 5.545 0.9984 3118233 ChemDiv3_004511 Cc1cccn2c(=O)c3cc(C(=O)NCC=C)c(=N)n(CC4CCCO4)c3nc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N02 compound treatment 1749268.0 952000.0 2.02 1863934.0 1150000.0 2.61 3.2697 0.9921 3118234 ChemDiv3_004512 CCC1CCc2nc3sc(C(=O)Nc4ccccc4C(F)(F)F)c(N)c3cc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N03 compound treatment 1261899.0 465000.0 0.99 1195911.0 478000.0 1.09 1.4652 0.9988 1874938 ChemDiv3_004513 N=c1c(cc2c(=O)n3ccccc3nc2n1CCCN4CCOCC4)C(=O)NCC5CCCO5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N04 compound treatment 1021739.0 225000.0 0.48 1015574.0 297000.0 0.68 0.8152 0.9853 3118235 ChemDiv3_004514 CCN(CC)c1ccc(NC(=O)c2cc(=O)c3ccccc3o2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N05 compound treatment 1135252.0 338000.0 0.72 938404.0 220000.0 0.5 0.8613 0.9846 3118369 ChemDiv3_004515 COc1cc(/C=C\2/S\C(=N\c3ccccc3)\N(CCc4ccccc4)C2=O)ccc1OCC(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N06 compound treatment 1246305.0 449000.0 0.95 1036841.0 319000.0 0.72 1.1861 0.9909 3024542 ChemDiv3_004516 CN1CCN(CC1)C(=S)c2cn(Cc3ccc(F)cc3)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N07 compound treatment 1208645.0 412000.0 0.87 1008150.0 290000.0 0.66 1.0835 0.9904 3118370 ChemDiv3_004517 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2nc3CC(C)(C)CC(=O)c3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N08 compound treatment 1328790.0 532000.0 1.13 1007351.0 289000.0 0.66 1.2623 0.9671 3024543 ChemDiv3_004518 CCOC(=O)Cn1c(=N)n(Cc2ccc(Cl)c(Cl)c2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N09 compound treatment 108680.0 -688000.0 -1.46 114745.0 -603000.0 -1.37 -2.0017 -0.9995 3024544 ChemDiv3_004519 CC1(C)N=C(N)N=C(N)N1c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N10 compound treatment 1301871.0 505000.0 1.07 1075913.0 358000.0 0.81 1.3322 0.9908 3118371 ChemDiv3_004520 Clc1ccc(cc1)N2CN=C(NC2=S)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N11 compound treatment 1407044.0 610000.0 1.29 1010686.0 293000.0 0.67 1.385 0.9522 3118372 ChemDiv3_004521 Cn1cc(C=C2C(=O)OC3(CCCCC3)OC2=O)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N12 compound treatment 1445389.0 648000.0 1.37 1098983.0 381000.0 0.87 1.5844 0.9752 3024545 ChemDiv3_004522 Cc1nc2-c3ccccc3C(=O)c2c(c1C#N)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N13 compound treatment 1616700.0 820000.0 1.74 1450988.0 733000.0 1.67 2.4071 0.9998 3024607 ChemDiv3_004523 CC1Oc2ccccc2C=C1/C=C/C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N14 compound treatment 1315909.0 519000.0 1.1 923396.0 205000.0 0.47 1.108 0.9271 1284692 ChemDiv3_004524 OC(=O)c1ccc(OC2CSC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N15 compound treatment 1257978.0 461000.0 0.98 867866.0 150000.0 0.34 0.9319 0.9004 1312878 ChemDiv3_004525 COc1cccc(C2CC(=NN2C(=O)CSC3CCCCC3)c4cccs4)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N16 compound treatment 388177.0 -409000.0 -0.87 383422.0 -335000.0 -0.76 -1.1508 -0.9979 3024608 ChemDiv3_004526 O=C(Oc1ccc2oc(=O)sc2c1)/C=C/c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N17 compound treatment 1325283.0 528000.0 1.12 864403.0 146000.0 0.33 1.0272 0.8791 3024609 ChemDiv3_004527 Cc1cc(C)nc(SCCS(=O)(=O)c2ccc(cc2)C(C)(C)C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N18 compound treatment 1468934.0 672000.0 1.42 1046692.0 329000.0 0.75 1.5356 0.9546 3024610 ChemDiv3_004528 CC(C)(C)c1cc(n2ncnc2n1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N19 compound treatment 1415134.0 618000.0 1.31 1077978.0 360000.0 0.82 1.5053 0.9743 3024611 ChemDiv3_004529 O=C1N=C2Nc3cc4ccccc4cc3NC=C2N1c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N20 compound treatment 1547309.0 750000.0 1.59 1033773.0 316000.0 0.72 1.6324 0.9353 3024612 ChemDiv3_004530 COC(=O)CSc1nnnn1c2ccc(cc2)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N21 compound treatment 1430712.0 634000.0 1.34 968892.0 251000.0 0.57 1.3533 0.9272 3118373 ChemDiv3_004531 CCOc1ccc(cc1)C(=O)/C=C\2/NCCNC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N22 compound treatment 1425566.0 629000.0 1.33 1006422.0 288000.0 0.66 1.4059 0.9466 1434883 ChemDiv3_004532 Fc1ccc(cc1)c2coc3cc4oc(=O)ccc4cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N23 mock treatment 1337811.0 541000.0 1.15 906902.0 189000.0 0.43 1.1143 0.9101 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 N24 mock treatment 771073.0 -25800.0 -0.05 548140.0 -170000.0 -0.39 -0.312 -0.7994 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O01 compound treatment 652591.0 -144000.0 -0.31 560095.0 -158000.0 -0.36 -0.4704 -0.9968 3118374 ChemDiv3_004533 CCNc1nc(OC)nc(Oc2ccc(/C=N/O)cc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O02 compound treatment 1111600.0 315000.0 0.67 926011.0 208000.0 0.47 0.806 0.9858 3024613 ChemDiv3_004534 CCOc1ccccc1NC2=NC(=O)CS2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O03 compound treatment 1130199.0 333000.0 0.71 1058811.0 341000.0 0.77 1.0473 0.9989 3118375 ChemDiv3_004535 COc1ccc(/C=C/C(=O)Nc2nc3ccc(cc3s2)S(=O)(=O)C)cc1Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O04 compound treatment 1200450.0 404000.0 0.86 1083978.0 366000.0 0.83 1.1931 0.9999 3024614 ChemDiv3_004536 Cc1ccc(cc1)n2cc(c3ccccc3)c4c(O)ncnc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O05 compound treatment 841193.0 44300.0 0.09 983816.0 266000.0 0.6 0.4935 0.8073 1788936 ChemDiv3_004537 COc1ccc(OCCn2c(NC(=O)c3ccccc3Cl)nc4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O06 compound treatment 1471792.0 675000.0 1.43 1379833.0 662000.0 1.5 2.0755 0.9997 1873162 ChemDiv3_004538 CCC(C)Nc1cc(C)c(C#N)c2nc3ccccc3n12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O07 compound treatment 1566016.0 769000.0 1.63 1154198.0 436000.0 0.99 1.854 0.9716 3118376 ChemDiv3_004539 CCOC(=O)c1sc(C)c2c(=O)[nH]c(nc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O08 compound treatment 1648033.0 851000.0 1.8 1511697.0 794000.0 1.8 2.5517 1.0 3118377 ChemDiv3_004540 CC(C)c1cc(NC(C)c2ccccc2)n3c4ccccc4nc3c1C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O09 compound treatment 1360487.0 564000.0 1.19 1079644.0 362000.0 0.82 1.426 0.9833 3024615 ChemDiv3_004541 COC(=O)c1ccc(CN2C(=O)/C(=N\O)/c3ccccc23)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O10 compound treatment 949694.0 153000.0 0.32 794206.0 76100.0 0.17 0.3514 0.9569 3118378 ChemDiv3_004542 COC(=O)c1ccc(cc1)C2N(C(=O)C(C)C)c3ccccc3NC4=C2C(=O)CC(C)(C)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O11 compound treatment 1438369.0 641000.0 1.36 1114331.0 396000.0 0.9 1.5986 0.98 1579211 ChemDiv3_004543 OCCNC(=O)N1c2ccccc2Sc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O12 compound treatment 1626696.0 830000.0 1.76 1351178.0 633000.0 1.44 2.2616 0.995 3024616 ChemDiv3_004544 CCOC(=O)c1cc(c2nnc(o2)c3cccc(C)c3)c(C)nc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O13 compound treatment 1293345.0 496000.0 1.05 1182176.0 464000.0 1.06 1.4902 1.0 3118379 ChemDiv3_004545 COC(=O)CCc1c(C)[nH]c(=S)[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O14 compound treatment 1342577.0 546000.0 1.16 1155193.0 437000.0 0.99 1.5207 0.9971 3118380 ChemDiv3_004546 OC(=O)COc1ccccc1C=C2C(=O)c3ccccc3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O15 compound treatment 1189081.0 392000.0 0.83 1107491.0 389000.0 0.89 1.2139 0.9995 1605579 ChemDiv3_004547 Cc1nn(c2ccccc2)c3sc(cc13)C(=O)N(Cc4ccccc4)Cc5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O16 compound treatment 1299057.0 502000.0 1.06 996640.0 279000.0 0.63 1.2005 0.9692 3118381 ChemDiv3_004548 COC(NC(=O)Nc1nc2ccccc2s1)(C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O17 compound treatment 1353170.0 556000.0 1.18 1131072.0 413000.0 0.94 1.4978 0.9936 3118382 ChemDiv3_004549 S(c1nnc([nH]1)c2ccccc2)c3ncnc4n(ncc34)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O18 compound treatment 762813.0 -34100.0 -0.07 652340.0 -65800.0 -0.15 -0.1568 -0.9444 1189918 ChemDiv3_004550 CCCc1nc2ccccc2n1CC(=O)N(COCC)c3c(C)cccc3CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O19 compound treatment 1157983.0 361000.0 0.77 1084418.0 366000.0 0.83 1.1302 0.9991 1251160 ChemDiv3_004551 COc1ccc(cc1)C(=O)N2CCc3cc(OC)c(OC)cc3C2c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O20 compound treatment 1315665.0 519000.0 1.1 1273049.0 555000.0 1.26 1.6698 0.9977 1160379 ChemDiv3_004552 Cc1ccc(NC(=O)CNS(=O)(=O)c2ccccc2)c(c1)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O21 compound treatment 1081021.0 284000.0 0.6 915121.0 197000.0 0.45 0.7426 0.9894 3118383 ChemDiv3_004553 Cc1ccc(cc1C)c2csc(NC3OC(=O)c4ccccc34)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O22 compound treatment 1164342.0 367000.0 0.78 1132116.0 414000.0 0.94 1.2164 0.9956 3118384 ChemDiv3_004554 CCOC(=O)c1ccccc1Oc2c(F)c(F)nc(NCCO)c2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O23 mock treatment 1034767.0 238000.0 0.5 988656.0 271000.0 0.62 0.7915 0.9951 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 O24 mock treatment 513584.0 -283000.0 -0.6 465863.0 -252000.0 -0.57 -0.8302 -0.9997 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P01 compound treatment 710089.0 -86800.0 -0.18 856773.0 139000.0 0.32 0.0928 0.2541 3118385 ChemDiv3_004555 Cc1ccc2nc3n(CC4CCCO4)c(=N)c(cc3c(=O)n2c1)C(=O)NCCN5CCOCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P02 compound treatment 682563.0 -114000.0 -0.24 900244.0 182000.0 0.41 0.1214 0.253 3024617 ChemDiv3_004556 CCC1CCc2nc3sc(C(=O)NC(C)c4ccccc4)c(N)c3cc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P03 compound treatment 1209250.0 412000.0 0.87 1610648.0 893000.0 2.03 2.053 0.9292 3024618 ChemDiv3_004557 CCCn1c(=N)c(cc2c(=O)n3ccccc3nc12)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P04 compound treatment 695807.0 -101000.0 -0.21 627686.0 -90400.0 -0.21 -0.2969 -0.9998 3118386 ChemDiv3_004558 COc1ccc(OC)c(c1)C(=O)CC2(O)C(=O)Nc3ccccc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P05 compound treatment 854379.0 57500.0 0.12 655877.0 -62200.0 -0.14 -0.0139 -0.0744 3118387 ChemDiv3_004559 CN/1C(=O)/C(=C\c2cccc(OCC(=O)O)c2)/S\C1=N\c3ccc(C)c(C)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P06 compound treatment 856118.0 59200.0 0.13 595308.0 -123000.0 -0.28 -0.1087 -0.355 3024619 ChemDiv3_004560 CN1C(=O)/C(=C/c2ccccc2OCc3ccc(cc3)C(=O)O)/NC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P07 compound treatment 954852.0 158000.0 0.33 565453.0 -153000.0 -0.35 -0.0086 -0.0179 3118388 ChemDiv3_004561 CC(C)C(=O)Nc1cccc(c1)C(=O)NC2CCSC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P08 compound treatment 257981.0 -539000.0 -1.14 283728.0 -434000.0 -0.99 -1.5062 -0.9974 3024620 ChemDiv3_004562 OCCn1c(=N)n(CCOc2ccc(Cl)cc2Cl)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P09 compound treatment 94689.0 -702000.0 -1.49 93528.0 -625000.0 -1.42 -2.0568 -0.9997 3118389 ChemDiv3_004563 Cc1ccc(NC2=NC(=NC(C)(C)N2)N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P10 compound treatment 725190.0 -71700.0 -0.15 670257.0 -47800.0 -0.11 -0.1844 -0.9865 1137559 ChemDiv3_004564 Clc1sc(nc1S(=O)(=O)c2ccccc2)N3CCCc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P11 compound treatment 719430.0 -77500.0 -0.16 625137.0 -93000.0 -0.21 -0.2656 -0.9922 3024621 ChemDiv3_004565 O=C(N1CCN(CC1)C2=NS(=O)(=O)c3ccccc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P12 compound treatment 712222.0 -84700.0 -0.18 684805.0 -33300.0 -0.08 -0.1805 -0.9263 3118390 ChemDiv3_004566 Clc1ccccc1/C=N/c2c(nc3ccccn23)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P13 compound treatment 578019.0 -219000.0 -0.46 625926.0 -92200.0 -0.21 -0.4763 -0.9355 3024622 ChemDiv3_004567 COc1cc2cc(cc(c3ccc(C)cc3)c2cc1OC)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P14 compound treatment 695660.0 -101000.0 -0.21 654820.0 -63300.0 -0.14 -0.2535 -0.9811 3118391 ChemDiv3_004568 CC(C)c1ccc(cc1)[C@@H]2Nc3ccc(cc3[C@@H]4C=CC[C@@H]42)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P15 compound treatment 506387.0 -291000.0 -0.62 575394.0 -143000.0 -0.32 -0.6649 -0.9552 1588117 ChemDiv3_004569 COc1cccc(C2CC(=NN2C(=O)CSc3nncn3C)c4cccs4)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P16 compound treatment 703763.0 -93200.0 -0.2 671849.0 -46200.0 -0.11 -0.214 -0.9565 1691077 ChemDiv3_004570 Cc1ccc(cc1)C(=O)Oc2ccc3oc(=O)sc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P17 compound treatment 157282.0 -640000.0 -1.36 141894.0 -576000.0 -1.31 -1.8852 -0.9999 1636095 ChemDiv3_004571 CCC[N+]1(C)CCC2C(C1)c3ccccc3N2Cc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P18 compound treatment 683213.0 -114000.0 -0.24 624882.0 -93200.0 -0.21 -0.3203 -0.9979 3024623 ChemDiv3_004572 C=CCN(CC=C)C(=S)Nc1ccc2nsnc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P19 compound treatment 805259.0 8340.0 0.02 737079.0 19000.0 0.04 0.043 0.9224 3118392 ChemDiv3_004573 Cc1cn(C/C=C\c2ccccc2)c(=O)n(C/C=C/c3ccccc3)c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P20 compound treatment 710243.0 -86700.0 -0.18 670739.0 -47400.0 -0.11 -0.2061 -0.9676 1171466 ChemDiv3_004574 CN1C(=O)C2ON(C(C2C1=O)c3ccc(C)cc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P21 compound treatment 762776.0 -34100.0 -0.07 629630.0 -88500.0 -0.2 -0.1934 -0.9048 3118510 ChemDiv3_004575 CCOc1ccc(cc1)C(=O)/C=C(\O)/C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P22 compound treatment 658850.0 -138000.0 -0.29 606362.0 -112000.0 -0.25 -0.3866 -0.9975 1689473 ChemDiv3_004576 COc1ccc(cc1F)c2coc3c(C)c4oc(=O)c5CCCCc5c4cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P23 mock treatment 571231.0 -226000.0 -0.48 548181.0 -170000.0 -0.39 -0.6115 -0.9944 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2013 P24 mock treatment 444791.0 -352000.0 -0.75 502377.0 -216000.0 -0.49 -0.8747 -0.9792 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A01 compound treatment 482831.0 -262000.0 -0.56 401187.0 -196000.0 -0.45 -0.7085 -0.9942 1460156 ChemDiv3_004577 Cc1c(Cc2ccccc2)c(=O)oc3cc4oc5CCCCc5c4cc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A02 compound treatment 470470.0 -274000.0 -0.58 411982.0 -186000.0 -0.42 -0.7097 -0.9876 3118511 ChemDiv3_004578 CCNc1nc(OCCO)nc(n1)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A03 compound treatment 707508.0 -37300.0 -0.08 473968.0 -124000.0 -0.28 -0.2547 -0.8721 1870447 ChemDiv3_004579 CCCc1cc(=O)oc2c(C)c3oc(C)c(C)c3cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A04 compound treatment 190865.0 -554000.0 -1.17 129115.0 -469000.0 -1.07 -1.5836 -0.9988 3118512 ChemDiv3_004580 Cc1cc(NCCNc2ccccc2)c3ccc4ccccc4c3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A05 compound treatment 621407.0 -123000.0 -0.26 734660.0 137000.0 0.31 0.0353 0.0868 3024624 ChemDiv3_004581 Fc1nc(Nc2ccccc2)c3Oc4ccccc4Oc3c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A06 compound treatment 150705.0 -594000.0 -1.26 100767.0 -497000.0 -1.13 -1.6893 -0.9985 3118513 ChemDiv3_004582 C[n+]1ccc(/C=C\c2ccco2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A07 compound treatment 460322.0 -284000.0 -0.6 475806.0 -122000.0 -0.28 -0.6223 -0.9377 3118514 ChemDiv3_004583 Fc1c(F)c2Oc3cc(Cl)c(Cl)cc3Oc2c(F)c1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A08 compound treatment 580636.0 -164000.0 -0.35 666596.0 69000.0 0.16 -0.1352 -0.3543 3024625 ChemDiv3_004584 CCc1ccc(cc1)C2Nc3sc4CN(C)CCc4c3C(=N2)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A09 compound treatment 499535.0 -245000.0 -0.52 487744.0 -110000.0 -0.25 -0.5443 -0.9436 1316234 ChemDiv3_004585 CN(C)c1ccc(cc1)C2C=C(Nc3ncnn23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A10 compound treatment 622974.0 -122000.0 -0.26 465346.0 -132000.0 -0.3 -0.3953 -0.9971 1745023 ChemDiv3_004586 COc1ccc(cc1)C(=O)CSc2nnc(c3ccco3)c(n2)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A11 compound treatment 531412.0 -213000.0 -0.45 543709.0 -53900.0 -0.12 -0.4066 -0.8675 1655325 ChemDiv3_004587 OC(=O)c1cc(NC(=O)CSc2ccccn2)cc(c1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A12 compound treatment 606376.0 -138000.0 -0.29 628533.0 30900.0 0.07 -0.1578 -0.5231 3024626 ChemDiv3_004588 CCC(Sc1nc(c([nH]1)c2ccccc2)c3ccccc3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A13 compound treatment 483832.0 -261000.0 -0.55 486638.0 -111000.0 -0.25 -0.5696 -0.9368 3118515 ChemDiv3_004589 CCC(Sc1nnc2c3ccccc3n(CC=C)c2n1)C(=O)Nc4nc5CCCCc5s4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A14 compound treatment 562407.0 -182000.0 -0.39 667402.0 69800.0 0.16 -0.1612 -0.3858 3024627 ChemDiv3_004590 CCSc1nnc(NC(=O)CCC(=O)OC2CCC(C)C(C)C2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A15 compound treatment 625362.0 -119000.0 -0.25 508669.0 -89000.0 -0.2 -0.3221 -0.9938 3118516 ChemDiv3_004591 COC(=O)c1ccccc1NC(=O)COC(=O)c2cc3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A16 compound treatment 446236.0 -299000.0 -0.63 513605.0 -84000.0 -0.19 -0.5826 -0.8813 3118517 ChemDiv3_004592 Cc1nc(C)c(o1)C(=O)/C=C\2/Nc3cc(Cl)ccc3OC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A17 compound treatment 165262.0 -580000.0 -1.23 193681.0 -404000.0 -0.92 -1.5182 -0.9897 3024628 ChemDiv3_004593 O=C(COc1ccc(cc1)c2nnc(N3CCCCC3)c4ccccc24)N5CCCCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A18 compound treatment 182044.0 -563000.0 -1.19 198802.0 -399000.0 -0.91 -1.4848 -0.9908 1446068 ChemDiv3_004594 CC1(C)C2CCC1(C)C(C2)OCC[N+]3(C)CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A19 compound treatment 112373.0 -632000.0 -1.34 143727.0 -454000.0 -1.03 -1.6777 -0.9916 3118518 ChemDiv3_004595 CN(C1=NC(=O)/C(=C/C(=C/c2ccccc2)/C)/S1)c3ccc(O)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A20 compound treatment 639985.0 -105000.0 -0.22 481511.0 -116000.0 -0.26 -0.3438 -0.9963 1566657 ChemDiv3_004596 CN(C)CCNC(=O)c1ccccn1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A21 compound treatment 124836.0 -620000.0 -1.31 163519.0 -434000.0 -0.99 -1.6272 -0.99 3024629 ChemDiv3_004597 Cc1cccc[n+]1C/C=C\c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A22 compound treatment 544093.0 -201000.0 -0.43 345063.0 -253000.0 -0.57 -0.7069 -0.9891 1268592 ChemDiv3_004598 O=C(Nc1ccccc1)N2c3ccccc3CCc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A23 mock treatment 556576.0 -188000.0 -0.4 339445.0 -258000.0 -0.59 -0.6972 -0.9823 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 A24 mock treatment 408670.0 -336000.0 -0.71 312809.0 -285000.0 -0.65 -0.9618 -0.9989 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B01 compound treatment 452159.0 -293000.0 -0.62 360079.0 -238000.0 -0.54 -0.8206 -0.9976 3118519 ChemDiv3_004599 CCCC1(CN2CC3(CCC)CN(C1)C2C(O)C(O)C(O)CO)C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B02 compound treatment 423852.0 -321000.0 -0.68 398751.0 -199000.0 -0.45 -0.8008 -0.9803 3024630 ChemDiv3_004600 O=C(/C=C/c1ccco1)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B03 compound treatment 176129.0 -569000.0 -1.21 140500.0 -457000.0 -1.04 -1.5874 -0.9973 1681379 ChemDiv3_004601 CCCN1CCc2c(C#N)c(NC(=S)NC(=O)c3ccccc3)sc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B04 compound treatment 770047.0 25300.0 0.05 778492.0 181000.0 0.41 0.3286 0.7925 3024754 ChemDiv3_004602 CCOc1ccc(cc1)C2=CC(c3cccc(OC)c3)c4ccccc4O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B05 compound treatment 703140.0 -41600.0 -0.09 818432.0 221000.0 0.5 0.2925 0.5739 1128626 ChemDiv3_004603 CCOC(=O)c1ccc2[nH]c3C(CCCc3c2c1)NC=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B06 compound treatment 814053.0 69300.0 0.15 953455.0 356000.0 0.81 0.6759 0.822 1152940 ChemDiv3_004604 CC(C)OC(=O)Cn1cnc2ccc(Br)cc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B07 compound treatment 747615.0 2830.0 0.01 816192.0 219000.0 0.5 0.3556 0.7156 1774881 ChemDiv3_004605 CCOC(=O)/C(=C\1/NC(=O)Nc2ccccc12)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B08 compound treatment 223003.0 -522000.0 -1.11 261657.0 -336000.0 -0.76 -1.3223 -0.9837 3118521 ChemDiv3_004606 COc1ccccc1N2CCN(CC2)C3CCN(Cc4cc(OC)c(OC)c(OC)c4)CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B09 compound treatment 799228.0 54400.0 0.12 855284.0 258000.0 0.59 0.4958 0.8305 1248651 ChemDiv3_004607 Cc1oc2ccc(NS(=O)(=O)c3ccc(C)cc3)cc2c1C(=O)NN 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B10 compound treatment 935112.0 190000.0 0.4 1028035.0 430000.0 0.98 0.9772 0.9233 3118522 ChemDiv3_004608 CCN1C(=O)C(=Cc2cccn2c3ccc(O)cc3)C(=O)N(CC)C1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B11 compound treatment 955825.0 211000.0 0.45 914331.0 317000.0 0.72 0.8255 0.9738 1683239 ChemDiv3_004609 CC(=O)N(c1ccc2oc3CCCCc3c2c1)S(=O)(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B12 compound treatment 883756.0 139000.0 0.29 932530.0 335000.0 0.76 0.7467 0.9146 3118523 ChemDiv3_004610 CC1(C)CC2(CC(C)(OC2=O)C(=O)CSc3nc4ccccc4s3)C(=O)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B13 compound treatment 746349.0 1560.0 0.0 840964.0 243000.0 0.55 0.3935 0.7113 1235086 ChemDiv3_004611 Clc1ccc(CCN2C(CC(=O)Nc3ccccc3)C(=O)N(Cc4ccccc4)C2=S)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B14 compound treatment 844542.0 99800.0 0.21 809692.0 212000.0 0.48 0.4904 0.9316 3024755 ChemDiv3_004612 COc1ccc(/C=C/2\SC(=N)NC2=O)cc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B15 compound treatment 668786.0 -76000.0 -0.16 680822.0 83200.0 0.19 0.0198 0.0797 1578381 ChemDiv3_004613 COc1ccc(CN2C(CC(=O)Nc3ccccc3)C(=O)N(C2=S)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B16 compound treatment 792176.0 47400.0 0.1 803653.0 206000.0 0.47 0.4022 0.8397 3024756 ChemDiv3_004614 COc1cccc(/C=C\2/NC(=O)N(Cc3ccc(F)cc3)C2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B17 compound treatment 664616.0 -80200.0 -0.17 679030.0 81400.0 0.19 0.0107 0.0424 3118524 ChemDiv3_004615 N/C(=N\C(=O)/C=C/c1ccccc1)/Nc2nc3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B18 compound treatment 780692.0 35900.0 0.08 905211.0 308000.0 0.7 0.5483 0.7795 3024757 ChemDiv3_004616 CCSc1nc2sc3COC(Cc3c2c(=O)n1c4ccc(OC)cc4)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B19 compound treatment 873763.0 129000.0 0.27 923752.0 326000.0 0.74 0.7176 0.9081 3118525 ChemDiv3_004617 N/C(=N\C(=O)c1cccc(Cl)c1)/Nc2nc3ccccc3s2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B20 compound treatment 849519.0 105000.0 0.22 939002.0 341000.0 0.78 0.7058 0.8743 3118526 ChemDiv3_004618 O=C(Nc1nnc(s1)C2CCCCC2)C3c4ccccc4Oc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B21 compound treatment 854954.0 110000.0 0.23 936888.0 339000.0 0.77 0.7105 0.8817 1556779 ChemDiv3_004619 CC(N1C(=O)c2ccccc2C1=O)C(=O)OCC(=O)n3c4CCCCc4c5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B22 compound treatment 824968.0 80200.0 0.17 932593.0 335000.0 0.76 0.6587 0.8442 3118527 ChemDiv3_004620 CCOc1ccc(cc1)c2nc3s/c(=C\C4=Cc5ccccc5OC4)/c(=O)n3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B23 mock treatment 698621.0 -46200.0 -0.1 773276.0 176000.0 0.4 0.2132 0.5184 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 B24 mock treatment 520998.0 -224000.0 -0.47 410655.0 -187000.0 -0.43 -0.6361 -0.9985 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C01 compound treatment 527804.0 -217000.0 -0.46 434202.0 -163000.0 -0.37 -0.588 -0.9944 1870380 ChemDiv3_004621 CCc1cc(=O)oc2c(C)c3occ(c4ccc(Cl)cc4)c3cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C02 compound treatment 783070.0 38300.0 0.08 634856.0 37200.0 0.08 0.1172 0.9998 3118528 ChemDiv3_004622 CCCOc1ccc(Oc2nc(nc(n2)N(C)C)N(C)C)nn1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C03 compound treatment 864361.0 120000.0 0.25 844588.0 247000.0 0.56 0.5762 0.9354 3024758 ChemDiv3_004623 COC(=O)N1N=C(CC(C)C)CC1(O)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C04 compound treatment 523628.0 -221000.0 -0.47 475110.0 -123000.0 -0.28 -0.5285 -0.9691 3118529 ChemDiv3_004624 CC(C)(C)C1=CC(=Nc2ccccc2N)C=C(C1O)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C05 compound treatment 951521.0 207000.0 0.44 858402.0 261000.0 0.59 0.7291 0.9889 3118650 ChemDiv3_004625 O=C1c2ccccc2-c3n[nH]c(=O)c4ccc(N5CCOCC5)c1c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C06 compound treatment 170325.0 -574000.0 -1.22 118236.0 -479000.0 -1.09 -1.6319 -0.9985 3024759 ChemDiv3_004626 C[n+]1ccc(/C=C/c2ccccc2F)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C07 compound treatment 889086.0 144000.0 0.31 897353.0 300000.0 0.68 0.6981 0.9347 3118651 ChemDiv3_004627 Fc1nc(N2CCOCC2)c(F)c(NC(=O)CCC(=O)N3CCOCC3)c1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C08 compound treatment 630279.0 -115000.0 -0.24 726608.0 129000.0 0.29 0.0357 0.0937 3024760 ChemDiv3_004628 COc1ccc(/C=C/2\SC(=NC2=O)N(C)c3ccc(Cl)cc3)c(OC)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C09 compound treatment 926515.0 182000.0 0.39 875757.0 278000.0 0.63 0.7195 0.9718 3118652 ChemDiv3_004629 Cn1c(nc2cccc3cccc1c32)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C10 compound treatment 1049320.0 305000.0 0.65 1122038.0 524000.0 1.19 1.2995 0.9585 3118653 ChemDiv3_004630 Cc1cc2/C(=c\3/sc4=NCN(Cn4c3=O)c5cccc(Br)c5)/C(=O)Nc2c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C11 compound treatment 1010784.0 266000.0 0.56 1091645.0 494000.0 1.12 1.1929 0.9492 1849841 ChemDiv3_004631 COc1cccc(NC(=O)CSc2nnc(N)s2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C12 compound treatment 620211.0 -125000.0 -0.26 677095.0 79500.0 0.18 -0.059 -0.1844 3118654 ChemDiv3_004632 COc1ccc(cc1)c2c(c3ccc(OC)cc3)c4c(O)ncnc4n2Cc5ccc(F)cc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C13 compound treatment 1055196.0 310000.0 0.66 1155500.0 558000.0 1.27 1.3621 0.9533 3024761 ChemDiv3_004633 Oc1ccc(=O)n(CN2CCC(Cc3ccccc3)CC2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C14 compound treatment 736827.0 -7960.0 -0.02 808044.0 210000.0 0.48 0.3263 0.6817 1873344 ChemDiv3_004634 Cc1cccc(NC(=O)CSc2nc3CC(C)(C)CC(=O)c3cc2C#N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C15 compound treatment 959002.0 214000.0 0.45 1128979.0 531000.0 1.21 1.1753 0.9107 3118655 ChemDiv3_004635 Clc1cccc(NC(=O)COC(=O)CCc2c[nH]c(=O)[nH]2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C16 compound treatment 522400.0 -222000.0 -0.47 546992.0 -50600.0 -0.12 -0.4148 -0.8547 3118656 ChemDiv3_004636 CC(C)CC(=O)/C=C\1/Nc2cc(Cl)ccc2OC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C17 compound treatment 891757.0 147000.0 0.31 1054630.0 457000.0 1.04 0.955 0.8804 3024762 ChemDiv3_004637 Clc1ccc(cc1)c2nn(CC(=O)Nc3cccc4ccccc34)c(=O)c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C18 compound treatment 324252.0 -421000.0 -0.89 310532.0 -287000.0 -0.65 -1.092 -0.9883 1281710 ChemDiv3_004638 CC1(C)C2CCC1(C)C(C2)OCC[N+]3(C)CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C19 compound treatment 892870.0 148000.0 0.31 1097312.0 500000.0 1.14 1.0253 0.8699 1406364 ChemDiv3_004639 O=c1sc2C3C(COc4ccccc34)CSc2n1c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C20 compound treatment 997540.0 253000.0 0.54 1134771.0 537000.0 1.22 1.2424 0.9316 3118657 ChemDiv3_004640 Clc1ccccc1C(=O)Nc2c3CCCCc3nc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C21 compound treatment 1008398.0 264000.0 0.56 1019282.0 422000.0 0.96 1.073 0.967 1056705 ChemDiv3_004641 CCOC(=O)C[n+]1ccccc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C22 compound treatment 862694.0 118000.0 0.25 955004.0 357000.0 0.81 0.7513 0.8838 3118658 ChemDiv3_004642 Clc1ccc2Sc3ccccc3N(C(=O)CCN4CCOCC4)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C23 mock treatment 822324.0 77500.0 0.16 837670.0 240000.0 0.55 0.5021 0.881 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 C24 mock treatment 606211.0 -139000.0 -0.29 456346.0 -141000.0 -0.32 -0.4349 -0.999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D01 compound treatment 236528.0 -508000.0 -1.08 225307.0 -372000.0 -0.85 -1.3605 -0.9929 3024797 ChemDiv3_004643 CCC1(CN2CC3(CC)CN(C1)C2c4ccc(cc4)C(C)C)C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D02 compound treatment 652767.0 -92000.0 -0.2 611647.0 14000.0 0.03 -0.1154 -0.584 3118659 ChemDiv3_004644 O=C(N1CCN=C1c2ccccc2)N3c4ccccc4Sc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D03 compound treatment 743684.0 -1110.0 0.0 782320.0 185000.0 0.42 0.2952 0.7032 3118660 ChemDiv3_004645 Cc1ccccc1n2c(SCC(=O)O)nc3sc4COC(C)(C)Cc4c3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D04 compound treatment 762624.0 17800.0 0.04 721271.0 124000.0 0.28 0.2255 0.7951 1163303 ChemDiv3_004646 CC(=O)Nc1ccc(cc1)n2c(C)nc(=O)c(c2C)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D05 compound treatment 714668.0 -30100.0 -0.06 813386.0 216000.0 0.49 0.3017 0.6099 3118661 ChemDiv3_004647 CCn1c2/C(=N/O)/CCCc2c3cc(Br)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D06 compound treatment 871022.0 126000.0 0.27 994901.0 397000.0 0.9 0.8279 0.8789 1215655 ChemDiv3_004648 CC(C)COC(=O)Cn1cnc2ccc(Br)cc2c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D07 compound treatment 742073.0 -2720.0 -0.01 766396.0 169000.0 0.38 0.2672 0.6964 3118662 ChemDiv3_004649 NC(=O)CCNCc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D08 compound treatment 724789.0 -20000.0 -0.04 922361.0 325000.0 0.74 0.4921 0.6654 3024798 ChemDiv3_004650 CC1CCCN(C1)C2CCN(Cc3ccccc3Cl)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D09 compound treatment 791411.0 46600.0 0.1 779520.0 182000.0 0.41 0.3623 0.8521 1184645 ChemDiv3_004651 Cc1cc(C)c(cc1C)S(=O)(=O)Nc2cc3c4C(=O)CCCc4oc3c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D10 compound treatment 416562.0 -328000.0 -0.7 470855.0 -127000.0 -0.29 -0.6958 -0.9239 3024799 ChemDiv3_004652 Oc1ccc(Br)cc1/C=N/c2cccc3nsnc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D11 compound treatment 936400.0 192000.0 0.41 960448.0 363000.0 0.82 0.8705 0.9468 3118663 ChemDiv3_004653 COc1ccc(NS(=O)(=O)c2ccc3SC(=O)c4cccc2c34)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D12 compound treatment 1069744.0 325000.0 0.69 1183063.0 585000.0 1.33 1.4283 0.953 3118664 ChemDiv3_004654 CC(CC1CC(C)(C)OC1=O)C(=O)Nc2nncs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D13 compound treatment 799257.0 54500.0 0.12 704095.0 106000.0 0.24 0.2528 0.9427 1338252 ChemDiv3_004655 CCN1C(=O)C(CC(=O)Nc2ccc(F)cc2)N(CCc3ccccc3)C1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D14 compound treatment 1087006.0 342000.0 0.73 1023269.0 426000.0 0.97 1.1973 0.9899 3118665 ChemDiv3_004656 CCSC1=N/C(=C\c2ccc(cc2)C(C)C)/C(=O)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D15 compound treatment 980562.0 236000.0 0.5 951443.0 354000.0 0.8 0.9222 0.9738 3024800 ChemDiv3_004657 NC(=O)C1CCN(CC1)C(=S)Nc2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D16 compound treatment 1029139.0 284000.0 0.6 975605.0 378000.0 0.86 1.0339 0.985 1485635 ChemDiv3_004658 CCn1c2ccccc2c3cc(NC(=O)c4ccccc4C)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D17 compound treatment 866845.0 122000.0 0.26 838464.0 241000.0 0.55 0.5701 0.9414 1155119 ChemDiv3_004659 Clc1ccc(NC(=O)Nc2nc(cs2)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D18 compound treatment 1210282.0 465000.0 0.99 1230299.0 633000.0 1.44 1.7149 0.9831 3118666 ChemDiv3_004660 CCOC(=O)c1c(NC(=O)c2ccccc2)sc3COC(Cc13)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D19 compound treatment 1131678.0 387000.0 0.82 890757.0 293000.0 0.67 1.0512 0.9947 1236887 ChemDiv3_004661 CC(=O)NC(=S)Nc1nc2ccccc2n1C(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D20 compound treatment 1077769.0 333000.0 0.71 867548.0 270000.0 0.61 0.9331 0.9976 3118667 ChemDiv3_004662 CC(C)c1nnc(NC(=O)/C=C/c2ccc3OCOc3c2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D21 compound treatment 1115308.0 371000.0 0.79 852503.0 255000.0 0.58 0.9651 0.9888 1788359 ChemDiv3_004663 COc1ccc(cc1)C(=O)OCC(=O)n2c(C)c(C)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D22 compound treatment 1019826.0 275000.0 0.58 885543.0 288000.0 0.65 0.8751 0.9983 3118668 ChemDiv3_004664 Cc1nn2c(=O)/c(=C/c3ccccc3)/sc2nc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D23 mock treatment 1007068.0 262000.0 0.56 708833.0 111000.0 0.25 0.5719 0.9364 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 D24 mock treatment 661994.0 -82800.0 -0.18 392567.0 -205000.0 -0.47 -0.4538 -0.9109 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E01 compound treatment 648010.0 -96800.0 -0.21 496105.0 -102000.0 -0.23 -0.3083 -0.9983 1865983 ChemDiv3_004665 COc1ccc(cc1)c2cc(=O)oc3cc4occ(c5cccc(OC)c5)c4cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E02 compound treatment 741573.0 -3220.0 -0.01 706011.0 108000.0 0.25 0.1694 0.6873 1539024 ChemDiv3_004666 O=C(NC1(CC2CC3CC(C2)C1)C3)c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E03 compound treatment 918022.0 173000.0 0.37 749300.0 152000.0 0.34 0.5035 0.9995 3118669 ChemDiv3_004667 CCOc1ccc(/N=C/2\C(=O)N(CN3CCCCC3)c4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E04 compound treatment 976384.0 232000.0 0.49 839388.0 242000.0 0.55 0.7358 0.9984 3024801 ChemDiv3_004668 CCNc1nc(NCC)nc(SCCOc2ccc(Br)cc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E05 compound treatment 1047817.0 303000.0 0.64 765376.0 168000.0 0.38 0.7239 0.969 3118670 ChemDiv3_004669 OC(=O)CNc1c(F)c(F)nc(F)c1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E06 compound treatment 158161.0 -587000.0 -1.24 115305.0 -482000.0 -1.1 -1.6548 -0.998 3024802 ChemDiv3_004670 C[n+]1ccc(/C=C/c2ccccc2O)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E07 compound treatment 995097.0 250000.0 0.53 813247.0 216000.0 0.49 0.7218 0.9992 3118671 ChemDiv3_004671 Fc1nc(N2CCCCC2)c(F)c(N3C(=O)CCC3=O)c1F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E08 compound treatment 1106165.0 361000.0 0.77 883711.0 286000.0 0.65 1.0016 0.9967 3118672 ChemDiv3_004672 Oc1ccc(/N=C\2/SC(CC(=O)Nc3ccccc3)C(=O)N2CC=C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E09 compound treatment 689142.0 -55600.0 -0.12 544048.0 -53600.0 -0.12 -0.1696 -0.9999 3024803 ChemDiv3_004673 CC1(C)CC(=O)/C(=C/c2ccccc2)/C(C)(C)N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E10 compound treatment 609397.0 -135000.0 -0.29 557832.0 -39800.0 -0.09 -0.267 -0.887 3118673 ChemDiv3_004674 COc1cc(cc(OC)c1OC)N2CN=c3s/c(=C\C=C\c4ccccc4)/c(=O)n3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E11 compound treatment 1039259.0 294000.0 0.62 950580.0 353000.0 0.8 1.0088 0.9923 3024804 ChemDiv3_004675 CCCc1cc(O)nc(SCC(=O)NCCc2ccccc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E12 compound treatment 1328174.0 583000.0 1.24 1113364.0 516000.0 1.17 1.7036 0.9996 1364723 ChemDiv3_004676 Cc1ccc(OCC(=O)NC2CC(C)(C)NC(C)(C)C2)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E13 compound treatment 989094.0 244000.0 0.52 1030710.0 433000.0 0.98 1.0624 0.955 3118674 ChemDiv3_004677 Cc1ccc(cc1)c2nnc(o2)c3cc(C(=O)NN)c(C)nc3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E14 compound treatment 1171680.0 427000.0 0.9 1136315.0 539000.0 1.22 1.5059 0.9889 3024845 ChemDiv3_004678 CC1(C)OC(=O)C(=CNc2ccccc2)C(=O)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E15 compound treatment 1023781.0 279000.0 0.59 1000958.0 403000.0 0.92 1.0666 0.9775 3118811 ChemDiv3_004679 COC(=O)c1ccc(NC(=O)CSc2nc(=O)cc(N)n2c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E16 compound treatment 1082700.0 338000.0 0.72 1158625.0 561000.0 1.28 1.4084 0.9628 3024846 ChemDiv3_004680 O/N=C/1\NC(=O)\C(=C/c2ccc(O)cc2)\S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E17 compound treatment 1031970.0 287000.0 0.61 1055000.0 457000.0 1.04 1.1658 0.9675 3118812 ChemDiv3_004681 FC(F)(F)c1cccc(NC(=O)Cn2nc(c3ccccc3)c4ccccc4c2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E18 compound treatment 731934.0 -12900.0 -0.03 699898.0 102000.0 0.23 0.1451 0.62 1283219 ChemDiv3_004682 CC1(C)C2CCC1(C)C(C2)NC(=O)CC[N+](C)(C)Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E19 compound treatment 1216592.0 472000.0 1.0 1120371.0 523000.0 1.19 1.5476 0.9963 3118813 ChemDiv3_004683 Brc1ccc(cc1)N2C(=O)C3Sc4[nH]c(=O)sc4C(/C=C/c5ccccc5)C3C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E20 compound treatment 1087788.0 343000.0 0.73 1022528.0 425000.0 0.97 1.1972 0.9902 3024848 ChemDiv3_004684 CN1CCCNC1c2ccc(o2)c3ccc(Br)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E21 compound treatment 1078217.0 333000.0 0.71 944241.0 347000.0 0.79 1.057 0.9985 3118814 ChemDiv3_004685 CCOC(=O)C[N+](C)(C)Cc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E22 compound treatment 976723.0 232000.0 0.49 957894.0 360000.0 0.82 0.9268 0.9702 1279489 ChemDiv3_004686 CCn1c(nc2ccccc12)c3nonc3N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E23 mock treatment 715246.0 -29500.0 -0.06 719697.0 122000.0 0.28 0.1519 0.5341 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 E24 mock treatment 622651.0 -122000.0 -0.26 419570.0 -178000.0 -0.4 -0.4694 -0.9767 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F01 compound treatment 495728.0 -249000.0 -0.53 497039.0 -101000.0 -0.23 -0.5351 -0.9299 3118815 ChemDiv3_004687 CCC1(CC)Cc2ccccc2-c3[nH]c4nnc(S)n4c(=O)c31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F02 compound treatment 604208.0 -141000.0 -0.3 641013.0 43400.0 0.1 -0.141 -0.4492 3024849 ChemDiv3_004688 COc1ccc(/C=C/C(=O)N2CCN=C2c3ccccc3)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F03 compound treatment 844473.0 99700.0 0.21 831114.0 233000.0 0.53 0.5248 0.9185 3118816 ChemDiv3_004689 COc1ccccc1n2c(=O)c3c4CCCc4sc3n5c(S)nnc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F04 compound treatment 982040.0 237000.0 0.5 1005847.0 408000.0 0.93 1.0119 0.9586 1684840 ChemDiv3_004690 Cc1cc(=O)oc2cc(OCC(=O)N)c(Cl)cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F05 compound treatment 971683.0 227000.0 0.48 861077.0 263000.0 0.6 0.7636 0.9941 1206179 ChemDiv3_004691 CC(C)c1ccc2[nH]c3C(O)CCCc3c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F06 compound treatment 931547.0 187000.0 0.4 849486.0 252000.0 0.57 0.6848 0.9838 3118817 ChemDiv3_004692 COc1cc(/C=C/C(=O)N2CCC(C)CC2)ccc1OCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F07 compound treatment 233338.0 -511000.0 -1.08 298509.0 -299000.0 -0.68 -1.2476 -0.9748 3024850 ChemDiv3_004693 O=C(C[n+]1ccccc1)Nc2c3CCCc3nc4CCCCc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F08 compound treatment 796312.0 51500.0 0.11 737514.0 140000.0 0.32 0.3021 0.8985 1604185 ChemDiv3_004694 COc1cccc(OC)c1C(=O)N2CCN(CC2)C(=O)COc3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F09 compound treatment 1095788.0 351000.0 0.74 894642.0 297000.0 0.68 1.0036 0.9988 3118818 ChemDiv3_004695 Cc1cc(ccc1Cl)S(=O)(=O)Nc2ccc3oc4CCC(Cc4c3c2)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F10 compound treatment 1211805.0 467000.0 0.99 983313.0 386000.0 0.88 1.3201 0.9982 1142903 ChemDiv3_004696 NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C(=O)N3CCCCC3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F11 compound treatment 1192075.0 447000.0 0.95 777884.0 180000.0 0.41 0.9603 0.9296 1284552 ChemDiv3_004697 CCOC(=O)c1c(oc2ccc(cc12)N(C(=O)C)S(=O)(=O)c3ccc(OC)cc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F12 compound treatment 1394171.0 649000.0 1.38 1345826.0 748000.0 1.7 2.1763 0.9945 3024851 ChemDiv3_004698 CC(CC1CC(C)OC1=O)C(=O)NC(=S)Nc2nncs2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F13 compound treatment 989104.0 244000.0 0.52 900833.0 303000.0 0.69 0.8537 0.9901 1398812 ChemDiv3_004699 COC(=O)CN1C(CC(=O)Nc2ccc(F)cc2)C(=O)N(C1=S)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F14 compound treatment 1364253.0 619000.0 1.31 1249644.0 652000.0 1.48 1.9768 0.9982 3024852 ChemDiv3_004700 CCOC(=O)COc1ccccc1/C=C/2\N=C(SCC)SC2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F15 compound treatment 1141070.0 396000.0 0.84 960936.0 363000.0 0.83 1.1781 1.0 1332272 ChemDiv3_004701 CCNC(=O)CC1N(NC(=O)c2ccccc2)C(=S)N(CC)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F16 compound treatment 1073396.0 329000.0 0.7 966980.0 369000.0 0.84 1.0864 0.9957 3118819 ChemDiv3_004702 CCn1c2ccccc2c3cc(NC(=O)Oc4ccccc4)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F17 compound treatment 1091482.0 347000.0 0.73 1099789.0 502000.0 1.14 1.327 0.9773 1303305 ChemDiv3_004703 COc1ccc2nc(SC(=O)c3ccccc3)nc(C)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F18 compound treatment 1187538.0 443000.0 0.94 1116159.0 519000.0 1.18 1.4973 0.9936 3118820 ChemDiv3_004704 CC(C)C1Cc2c(CO1)sc3nc(SCc4ccc(Cl)c(Cl)c4)nc(N)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F19 compound treatment 1232592.0 488000.0 1.03 999056.0 401000.0 0.91 1.3766 0.9981 3024853 ChemDiv3_004705 CCc1ccc2NC(=O)N(C(=C)c2c1)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F20 compound treatment 1212432.0 468000.0 0.99 948001.0 350000.0 0.8 1.2643 0.9941 3118821 ChemDiv3_004706 COCc1nnc(NC(=O)/C=C/c2ccc3OCOc3c2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F21 compound treatment 954950.0 210000.0 0.45 856226.0 259000.0 0.59 0.7308 0.9906 1870814 ChemDiv3_004707 Fc1ccc(Nc2nc(Nc3ccc(F)cc3)nc(n2)N4CCCCC4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F22 compound treatment 1118732.0 374000.0 0.79 882399.0 285000.0 0.65 1.0183 0.9949 3118822 ChemDiv3_004708 O=c1/c(=C/c2cccs2)/sc3nc(=O)c(Cc4ccccc4)nn13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F23 mock treatment 971492.0 227000.0 0.48 692431.0 94800.0 0.22 0.4922 0.9345 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 F24 mock treatment 476359.0 -268000.0 -0.57 411906.0 -186000.0 -0.42 -0.701 -0.9892 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G01 compound treatment 677105.0 -67700.0 -0.14 551312.0 -46300.0 -0.11 -0.1759 -0.9884 1867727 ChemDiv3_004709 CCCCc1cc(=O)oc2cc3oc4CCCCc4c3cc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G02 compound treatment 880022.0 135000.0 0.29 793374.0 196000.0 0.45 0.5174 0.9774 3118823 ChemDiv3_004710 Cc1ccccc1OCc2nnc3c4cnn(Cc5ccccc5)c4ncn23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G03 compound treatment 874958.0 130000.0 0.28 754431.0 157000.0 0.36 0.4472 0.992 3118824 ChemDiv3_004711 CC1CCN(CN2C(=O)/C(=N\c3ccccc3C)/c4ccccc24)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G04 compound treatment 1059068.0 314000.0 0.67 838845.0 241000.0 0.55 0.8589 0.9953 3024855 ChemDiv3_004712 CCNc1nc(OCC=C)nc(n1)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G05 compound treatment 1128367.0 384000.0 0.81 829018.0 231000.0 0.53 0.947 0.9778 3118825 ChemDiv3_004713 Fc1nc(OCC=C)c2Oc3cc(Br)c(Br)cc3Oc2c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G06 compound treatment 139556.0 -605000.0 -1.28 114760.0 -483000.0 -1.1 -1.6836 -0.997 3024856 ChemDiv3_004714 Oc1ccccc1/C=C/c2cc[n+](CC=C)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G07 compound treatment 960935.0 216000.0 0.46 1032497.0 435000.0 0.99 1.0231 0.9389 3118826 ChemDiv3_004715 COc1ccccc1/C=C/C(=O)Nc2nc(N)n(n2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G08 compound treatment 1183233.0 438000.0 0.93 1025409.0 428000.0 0.97 1.3449 0.9997 3024857 ChemDiv3_004716 Oc1ccc(/N=C\2/SCC(=O)N2CC=C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G09 compound treatment 1148769.0 404000.0 0.86 1127160.0 530000.0 1.2 1.4569 0.9861 3118827 ChemDiv3_004717 CC1(C)NC(C)(C)C(=C1)C(=O)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G10 compound treatment 1190444.0 446000.0 0.94 997046.0 399000.0 0.91 1.3102 0.9998 3024858 ChemDiv3_004718 Cc1cc(C)cc(c1)N2C(SCC2=O)c3cccs3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G11 compound treatment 1433075.0 688000.0 1.46 1056558.0 459000.0 1.04 1.7695 0.9865 3118828 ChemDiv3_004719 COc1ccc(cc1NC(=S)NC(=O)Cc2ccc(Cl)cc2)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G12 compound treatment 591014.0 -154000.0 -0.33 518684.0 -79000.0 -0.18 -0.3574 -0.9605 3024899 ChemDiv3_004720 COc1cccc(/C=C/2\CC(C)C/C(=C\c3ccccc3OC)/C2=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G13 compound treatment 206136.0 -539000.0 -1.14 244826.0 -353000.0 -0.8 -1.3747 -0.9851 3118829 ChemDiv3_004721 CCCc1n(CC(O)COc2ccccc2C)c3ccccc3[n+]1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G14 compound treatment 1228979.0 484000.0 1.03 1221035.0 623000.0 1.42 1.728 0.9875 3024900 ChemDiv3_004722 CC(C)n1nc(O)c2C(SCC(=O)Nc21)c3ccc(Br)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G15 compound treatment 1298645.0 554000.0 1.17 1108720.0 511000.0 1.16 1.6519 1.0 3118830 ChemDiv3_004723 CN(/C(=N/S(=O)(=O)c1ccc(C)cc1)/c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G16 compound treatment 1083617.0 339000.0 0.72 997011.0 399000.0 0.91 1.15 0.9933 3024901 ChemDiv3_004724 CCOC(=O)CN1C(=O)S/C(=C\c2ccc(cc2)C(=O)O)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G17 compound treatment 1051822.0 307000.0 0.65 1275296.0 678000.0 1.54 1.5497 0.9265 3118831 ChemDiv3_004725 CCN(CC)S(=O)(=O)c1cc(ccc1C)c2nn(C)c(=O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G18 compound treatment 1197903.0 453000.0 0.96 1430725.0 833000.0 1.89 2.0185 0.9505 3024902 ChemDiv3_004726 COC(=O)COc1ccc(Oc2nc(SC)nc(n2)N(C)C)nn1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G19 compound treatment 1269875.0 525000.0 1.11 1023836.0 426000.0 0.97 1.4723 0.9976 1436626 ChemDiv3_004727 COc1cc2CCN(Cc2cc1OC)C(=S)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G20 compound treatment 1156693.0 412000.0 0.87 1169189.0 572000.0 1.3 1.5363 0.9813 3118832 ChemDiv3_004728 CN(C)c1ccc(/C=C\2/S/C(=N/O)/NC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G21 compound treatment 1192691.0 448000.0 0.95 1018757.0 421000.0 0.96 1.3484 1.0 3024903 ChemDiv3_004729 CCCOc1ccc(=O)n(C)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G22 compound treatment 1192009.0 447000.0 0.95 1142442.0 545000.0 1.24 1.5462 0.9913 3024904 ChemDiv3_004730 COC(=O)Cn1c2ccc(Cl)cc2c3nc4ccccc4nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G23 mock treatment 835930.0 91100.0 0.19 844153.0 247000.0 0.56 0.5329 0.899 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 G24 mock treatment 628713.0 -116000.0 -0.25 455345.0 -142000.0 -0.32 -0.4028 -0.9909 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H01 compound treatment 511622.0 -233000.0 -0.49 512515.0 -85100.0 -0.19 -0.4864 -0.9162 3118833 ChemDiv3_004731 CC1(C)Cc2ccccc2-c3c1c(=O)n(Cc4ccccc4)c5nnc(S)n35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H02 compound treatment 452995.0 -292000.0 -0.62 513432.0 -84200.0 -0.19 -0.5728 -0.8846 1871178 ChemDiv3_004732 O=C(Oc1cccc2cccnc12)N3c4ccccc4Sc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H03 compound treatment 770225.0 25400.0 0.05 840106.0 242000.0 0.55 0.4279 0.7726 3024905 ChemDiv3_004733 CC(C)C1Cc2c(CO1)sc3nc(SCC(=O)Nc4ccccc4)nc(N)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H04 compound treatment 874733.0 130000.0 0.28 858659.0 261000.0 0.59 0.6144 0.9391 1556837 ChemDiv3_004734 CC(C)C(N1C(=O)c2ccccc2C1=O)C(=O)Nc3ccc(cc3)S(=O)(=O)Nc4ncccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H05 compound treatment 876821.0 132000.0 0.28 971152.0 374000.0 0.85 0.7984 0.8929 3024907 ChemDiv3_004735 Cc1ccc2[nH]c3/C(=N\CC=C)/CCCc3c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H06 compound treatment 1090328.0 346000.0 0.73 1191139.0 593000.0 1.35 1.4721 0.9588 1227251 ChemDiv3_004736 COc1cc(cc(OC)c1OC)C(=O)OCC(=O)Nc2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H07 compound treatment 858633.0 114000.0 0.24 922604.0 325000.0 0.74 0.6931 0.8917 3118962 ChemDiv3_004737 COc1ccc(/C=C/C(=O)Nc2c3CCCc3nc4CCCCc24)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H08 compound treatment 1029815.0 285000.0 0.6 971827.0 374000.0 0.85 1.0288 0.986 3024908 ChemDiv3_004738 CCCOC(=O)CSc1nc(N)c(C#N)c(c1C#N)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H09 compound treatment 1144483.0 400000.0 0.85 1176796.0 579000.0 1.32 1.5302 0.9773 1320144 ChemDiv3_004739 Cc1cc(ccc1Cl)S(=O)(=O)Nc2cc(Br)c3oc4CCCC(=O)c4c3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H10 compound treatment 1106086.0 361000.0 0.77 1080680.0 483000.0 1.1 1.3182 0.9845 1303471 ChemDiv3_004740 O=C1N(CNc2ccccc2)CCN1CNc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H11 compound treatment 1275168.0 530000.0 1.12 1080361.0 483000.0 1.1 1.5711 0.9999 1244728 ChemDiv3_004741 Cc1ccc(C)c(c1)S(=O)(=O)Nc2ccc3oc4CCC(Cc4c3c2)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H12 compound treatment 1118920.0 374000.0 0.79 1447147.0 850000.0 1.93 1.9265 0.9227 3118963 ChemDiv3_004742 CCOc1ccc(Nc2nc(cs2)C3(C)CC4(CC(C)(C)OC4=O)C(=O)O3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H13 compound treatment 1069574.0 325000.0 0.69 938089.0 340000.0 0.77 1.0342 0.9983 3024909 ChemDiv3_004743 CCN/1C(=O)CC(S\C1=N/c2ccccc2)C(=O)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H14 compound treatment 1357094.0 612000.0 1.3 1353790.0 756000.0 1.72 2.1335 0.9904 3024910 ChemDiv3_004744 CCSC1=N/C(=C\c2cc(Br)c(OC(=O)C)c(OC)c2)/C(=O)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H15 compound treatment 103956.0 -641000.0 -1.36 136841.0 -461000.0 -1.05 -1.7014 -0.9918 1580209 ChemDiv3_004745 COC(=O)CN1C(CC(=O)Nc2ccc(OC)cc2)C(=O)N(Cc3ccccc3)C1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H16 compound treatment 1296125.0 551000.0 1.17 1167787.0 570000.0 1.3 1.7431 0.9987 3024911 ChemDiv3_004746 O=C(NCc1ccc2OCOc2c1)Oc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H17 compound treatment 150290.0 -594000.0 -1.26 169447.0 -428000.0 -0.97 -1.5796 -0.9919 3118964 ChemDiv3_004747 N(c1ccccc1)c2nc(Nc3ccccc3)nc(Sc4nc5ccccc5[nH]4)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H18 compound treatment 1388883.0 644000.0 1.37 990760.0 393000.0 0.89 1.5975 0.9789 3118965 ChemDiv3_004748 CSc1nc2sc3COC(C)(C)Cc3c2c(=O)n1c4cccc(Br)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H19 compound treatment 1066055.0 321000.0 0.68 982678.0 385000.0 0.88 1.1006 0.9923 1787885 ChemDiv3_004749 O=C(N1c2ccccc2Sc3ccccc13)c4ccncc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H20 compound treatment 937239.0 192000.0 0.41 811459.0 214000.0 0.49 0.6322 0.9962 3118966 ChemDiv3_004750 COCc1nnc(NC(=O)/C=C/c2cc(OC)c(OC)c(OC)c2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H21 compound treatment 999983.0 255000.0 0.54 863885.0 266000.0 0.61 0.8106 0.9984 3024912 ChemDiv3_004751 N/C(=N/C=C1C(=O)NC(=O)NC1=O)/Nc2nc3ccccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H22 compound treatment 947083.0 202000.0 0.43 944965.0 347000.0 0.79 0.8616 0.9588 3118967 ChemDiv3_004752 Cc1nn2c(=O)/c(=C/C=C/c3ccccc3)/sc2nc1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H23 mock treatment 903369.0 159000.0 0.34 837671.0 240000.0 0.55 0.6236 0.9729 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 H24 mock treatment 496768.0 -248000.0 -0.53 463812.0 -134000.0 -0.3 -0.5869 -0.9662 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I01 compound treatment 769772.0 25000.0 0.05 646663.0 49000.0 0.11 0.1163 0.9422 1277008 ChemDiv3_004753 O=c1oc2cc3occ(c4ccccc4)c3cc2c5ccccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I02 compound treatment 1129612.0 385000.0 0.82 1016693.0 419000.0 0.95 1.2505 0.997 3118968 ChemDiv3_004754 Cc1ccc(cc1)c2nnc3c4cnn(c5ccccc5)c4ncn23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I03 compound treatment 1252719.0 508000.0 1.08 1117249.0 520000.0 1.18 1.5967 0.9989 3024913 ChemDiv3_004755 N/C(=N/O)/CC(=O)Nc1cccc(c1)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I04 compound treatment 979501.0 235000.0 0.5 864863.0 267000.0 0.61 0.7814 0.9951 3118969 ChemDiv3_004756 Cc1c(NC(=O)Nc2ccc(C)cc2)sc(=S)n1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I05 compound treatment 1023339.0 279000.0 0.59 955046.0 357000.0 0.81 0.9921 0.9877 3024914 ChemDiv3_004757 Brc1cnc(nc1N2CCOCC2)N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I06 compound treatment 1275720.0 531000.0 1.13 1082013.0 484000.0 1.1 1.5746 0.9999 3118970 ChemDiv3_004758 OC(=O)CC(NCc1ccccc1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I07 compound treatment 1452495.0 708000.0 1.5 1339135.0 741000.0 1.69 2.2529 0.9983 3118971 ChemDiv3_004759 OC(=O)CCC(=O)Nc1nc2NC(=O)CC(c3ccccc3)n2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I08 compound treatment 1529307.0 785000.0 1.66 1130491.0 533000.0 1.21 2.0327 0.9879 3024915 ChemDiv3_004760 COc1cc(/C=C/2\SC(=NC2=O)N(C)c3ccc(O)cc3)ccc1OCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I09 compound treatment 1480560.0 736000.0 1.56 1280524.0 683000.0 1.55 2.2008 1.0 1474160 ChemDiv3_004761 Clc1cccc(NC(=O)Nc2ccc3c(c2)oc4ccccc43)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I10 compound treatment 1332581.0 588000.0 1.25 991423.0 394000.0 0.9 1.5142 0.9868 3118972 ChemDiv3_004762 COc1ccc(cc1OC)C2NC(=S)NC(=C2)c3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I11 compound treatment 1206069.0 461000.0 0.98 1311666.0 714000.0 1.62 1.8394 0.9706 3118973 ChemDiv3_004763 NC(=O)c1ccccc1OCC(=O)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I12 compound treatment 1179160.0 434000.0 0.92 951650.0 354000.0 0.8 1.2203 0.9977 1870736 ChemDiv3_004764 COc1ccc2[nH]c3C(NCCc3c2c1)C4CCC(=CC4)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I13 compound treatment 1285129.0 540000.0 1.15 1332720.0 735000.0 1.67 1.9917 0.983 1866294 ChemDiv3_004765 OC(COc1ccc(Br)cc1)Cn2ccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I14 compound treatment 1238476.0 494000.0 1.05 1523765.0 926000.0 2.11 2.2289 0.9479 3118974 ChemDiv3_004766 COc1ccc(CNCC(C)NCc2ccc(OC)c(OC)c2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I15 compound treatment 1315842.0 571000.0 1.21 1141416.0 544000.0 1.24 1.7302 0.9999 3024962 ChemDiv3_004767 Cc1ccc(cc1S(=O)(=O)NCc2cccnc2)c3nnc(S)c4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I16 compound treatment 1439839.0 695000.0 1.47 1260725.0 663000.0 1.51 2.1079 0.9999 3118975 ChemDiv3_004768 CN1C(=O)S/C(=C/c2ccccc2OCc3ccc(cc3)C(=O)O)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I17 compound treatment 1569952.0 825000.0 1.75 1575800.0 978000.0 2.22 2.8095 0.9929 3024963 ChemDiv3_004769 Cc1ccc(cc1S(=O)(=O)N2CCOCC2)c3nn(C)c(=O)c4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I18 compound treatment 1313774.0 569000.0 1.21 1423960.0 826000.0 1.88 2.1814 0.9771 3118976 ChemDiv3_004770 CC(CC(=O)O)CC(=O)Nc1ccccc1C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I19 compound treatment 1302666.0 558000.0 1.18 1173525.0 576000.0 1.31 1.7621 0.9987 1470431 ChemDiv3_004771 CCOc1ccc(cc1)C(=O)N2CCc3cc(OC)c(OC)cc3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I20 compound treatment 1317904.0 573000.0 1.21 1267497.0 670000.0 1.52 1.936 0.9937 3024964 ChemDiv3_004772 CC(CN1CCCCC1)OC(=O)C2c3ccccc3Oc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I21 compound treatment 1563183.0 818000.0 1.73 1480484.0 883000.0 2.01 2.6461 0.9974 3118977 ChemDiv3_004773 CCSc1nc(SCC)c2c3CCCCc3[nH]c2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I22 compound treatment 1296350.0 552000.0 1.17 1230004.0 632000.0 1.44 1.8434 0.9947 3024965 ChemDiv3_004774 CC(C)n1c2ccc(Cl)cc2c3nc4ccccc4nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I23 mock treatment 1142428.0 398000.0 0.84 1128478.0 531000.0 1.21 1.4495 0.9846 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 I24 mock treatment 568858.0 -176000.0 -0.37 522129.0 -75500.0 -0.17 -0.3851 -0.938 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J01 compound treatment 619823.0 -125000.0 -0.26 769180.0 172000.0 0.39 0.0884 0.1876 1370693 ChemDiv3_004775 OC(=O)CCNC(=O)c1cccnc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J02 compound treatment 749694.0 4910.0 0.01 892867.0 295000.0 0.67 0.482 0.718 3118978 ChemDiv3_004776 CC1=CC(C)(C)N(C(=O)/C=C/c2ccccc2)c3ccc(C)cc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J03 compound treatment 1104596.0 360000.0 0.76 990455.0 393000.0 0.89 1.1709 0.9969 1327411 ChemDiv3_004777 Fc1ccc(Nc2cccc3nonc23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J04 compound treatment 1036103.0 291000.0 0.62 1095949.0 498000.0 1.13 1.2378 0.9593 1573339 ChemDiv3_004778 COc1ccccc1c2coc3cc(OCC(=O)OCC(C)C)ccc3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J05 compound treatment 93005.0 -652000.0 -1.38 149137.0 -449000.0 -1.02 -1.6981 -0.9888 1494509 ChemDiv3_004779 Cc1ccc2[nH]c3C(CCCc3c2c1)NC4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J06 compound treatment 1496900.0 752000.0 1.59 1210912.0 613000.0 1.39 2.1134 0.9978 3118979 ChemDiv3_004780 Cc1cccc(NC(=O)COC(=O)/C=C/c2ccc(F)cc2)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J07 compound treatment 1227959.0 483000.0 1.02 1013888.0 416000.0 0.95 1.3935 0.9992 3119110 ChemDiv3_004781 NC(=O)CN1C(=O)C2(C(=C(N)OC3=C2C(=O)CCC3)C#N)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J08 compound treatment 1178206.0 433000.0 0.92 1032651.0 435000.0 0.99 1.349 0.9993 3024966 ChemDiv3_004782 CC(C)c1ccc(/C=C/C(=O)NC(=S)Nc2ccc(cc2)C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J09 compound treatment 115908.0 -629000.0 -1.33 132330.0 -465000.0 -1.06 -1.6908 -0.9934 3119111 ChemDiv3_004783 CCc1ccc(cc1)S(=O)(=O)/N=C\2/C=C(Nc3ccccc3)C(=O)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J10 compound treatment 1480742.0 736000.0 1.56 1179637.0 582000.0 1.32 2.0389 0.9966 3024967 ChemDiv3_004784 Cc1ccc(cc1)S(=O)(=O)c2cc3c(=O)n4ccccc4nc3n(Cc5ccccc5)c2=N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J11 compound treatment 1855279.0 1110000.0 2.35 1454418.0 857000.0 1.95 3.0421 0.9956 1676345 ChemDiv3_004785 CC(C)c1ccc(cc1)S(=O)(=O)Nc2cc3c4CCCCc4oc3c5ccccc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J12 compound treatment 1862418.0 1120000.0 2.37 1353714.0 756000.0 1.72 2.8909 0.9876 3119112 ChemDiv3_004786 Cc1ccc(cc1)C2=NNC(=O)C(C2)P(=O)(c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J13 compound treatment 1647895.0 903000.0 1.91 1230228.0 633000.0 1.44 2.3708 0.9901 1618837 ChemDiv3_004787 OC(C1CCN(CC1)C(=S)Nc2ccccc2)(c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J14 compound treatment 1768223.0 1020000.0 2.17 1397832.0 800000.0 1.82 2.8206 0.9962 3024968 ChemDiv3_004788 CC/1=NOC(=O)\C1=C/C=C\c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J15 compound treatment 143741.0 -601000.0 -1.27 111073.0 -487000.0 -1.11 -1.6832 -0.9975 3119113 ChemDiv3_004789 Fc1ccc(CCN2C(CC(=O)Nc3ccc(F)cc3)C(=O)N(C2=S)c4ccccc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J16 compound treatment 1057371.0 313000.0 0.66 947561.0 350000.0 0.8 1.0311 0.9959 1548968 ChemDiv3_004790 CCn1c2ccccc2c3cc(NC(=O)CCC4CCCCC4)ccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J17 compound treatment 1553404.0 809000.0 1.71 1248795.0 651000.0 1.48 2.259 0.9973 3024969 ChemDiv3_004791 COc1ccccc1C(=O)n2nc(C)cc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J18 compound treatment 1957168.0 1210000.0 2.57 1267878.0 670000.0 1.52 2.8949 0.9689 3119114 ChemDiv3_004792 Cc1cccc(c1)n2c(=O)c3c4CCCCc4sc3n5c(S)nnc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J19 compound treatment 756126.0 11300.0 0.02 661724.0 64100.0 0.15 0.12 0.8128 3024970 ChemDiv3_004793 CC1(C)CC(C)(c2ccc(Cl)cc2)c3ccccc3N1C(=O)c4cccnc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J20 compound treatment 1312730.0 568000.0 1.2 1020297.0 423000.0 0.96 1.5308 0.9938 3119115 ChemDiv3_004794 O=c1/c(=C/c2ccccc2)/sc3nc(nn13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J21 compound treatment 1343478.0 599000.0 1.27 980816.0 383000.0 0.87 1.5135 0.9831 3024971 ChemDiv3_004795 Cc1ccc(/N=C(\N)/Nc2nc(=O)cc(C)[nH]2)c(C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J22 compound treatment 1325540.0 581000.0 1.23 997078.0 399000.0 0.91 1.5127 0.9888 3119116 ChemDiv3_004796 CCCN1C(=O)/C(=c/2\sc3nc(=O)c(nn3c2=O)c4ccccc4)/c5ccccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J23 mock treatment 1154992.0 410000.0 0.87 913199.0 316000.0 0.72 1.1222 0.9954 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 J24 mock treatment 591856.0 -153000.0 -0.32 487761.0 -110000.0 -0.25 -0.4059 -0.9917 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K01 compound treatment 702481.0 -42300.0 -0.09 680505.0 82900.0 0.19 0.0698 0.3345 1870397 ChemDiv3_004797 COc1ccc(cc1)c2coc3c(C)c4oc(=O)c5cc(OC)ccc5c4cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K02 compound treatment 1095083.0 350000.0 0.74 867059.0 269000.0 0.61 0.9582 0.9954 3119117 ChemDiv3_004798 COc1ccc(cc1)c2nc3c4cnn(c5cccc(C)c5)c4ncn3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K03 compound treatment 1261521.0 517000.0 1.1 1059630.0 462000.0 1.05 1.5173 0.9998 1862416 ChemDiv3_004799 CCCCC(=O)Nc1ccc2oc(nc2c1)c3ccc(O)c(Br)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K04 compound treatment 1123061.0 378000.0 0.8 981639.0 384000.0 0.87 1.1844 0.9991 3024972 ChemDiv3_004800 CCSc1nc2sc3CCCCc3c2c4nnc(S)n14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K05 compound treatment 676833.0 -68000.0 -0.14 600473.0 2830.0 0.01 -0.0973 -0.6748 3119118 ChemDiv3_004801 Oc1ccccc1Oc2c(F)c(F)nc(N3CCCC3)c2F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K06 compound treatment 1137046.0 392000.0 0.83 1065815.0 468000.0 1.06 1.3407 0.9925 3024973 ChemDiv3_004802 Cc1ccccc1OCCn2cc(/C(=N/O)/N)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K07 compound treatment 1379552.0 635000.0 1.35 1228586.0 631000.0 1.43 1.9659 0.9995 3119119 ChemDiv3_004803 O=C1CCC(=O)N1c2nc3NC(=O)CC(c4ccccc4)n3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K08 compound treatment 1287307.0 543000.0 1.15 1092251.0 495000.0 1.12 1.6084 0.9999 3024974 ChemDiv3_004804 CC1(C)Cc2nc3sc4c(=O)n(CC(=O)c5ccc(Cl)cc5)cnc4c3cc2CO1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K09 compound treatment 1402020.0 657000.0 1.39 1123552.0 526000.0 1.2 1.8307 0.9971 1204823 ChemDiv3_004805 COc1ccc(CNC(=O)NC(C)(C)c2cccc(c2)C(=C)C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K10 compound treatment 2149538.0 1400000.0 2.98 2238971.0 1640000.0 3.73 4.7444 0.9938 3119120 ChemDiv3_004806 CCCC(=O)Nc1ccc(cc1)c2nc3cc4ccccc4cc3[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K11 compound treatment 1516767.0 772000.0 1.64 1593417.0 996000.0 2.26 2.7581 0.9873 3024127 ChemDiv3_004807 CCOc1nc(NCC=C)nc(Nc2ccc(cc2)c3nc4ccccc4o3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K12 compound treatment 1066553.0 322000.0 0.68 1041933.0 444000.0 1.01 1.1966 0.9817 1545881 ChemDiv3_004808 Cn1ccnc1SCC(=O)Nc2cccc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K13 compound treatment 1220352.0 476000.0 1.01 1123418.0 526000.0 1.2 1.5581 0.9964 1325413 ChemDiv3_004809 C=CCNC(=S)N1CCN(CC1)C(c2ccccc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K14 compound treatment 1433258.0 688000.0 1.46 1143307.0 546000.0 1.24 1.9093 0.9967 3119121 ChemDiv3_004810 CC(CNCc1ccc2OCOc2c1)NCc3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K15 compound treatment 1439438.0 695000.0 1.47 1073217.0 476000.0 1.08 1.8059 0.9885 3119122 ChemDiv3_004811 CCOc1ccc(cc1)c2nnc(N3CCCCC3)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K16 compound treatment 1287744.0 543000.0 1.15 1094068.0 496000.0 1.13 1.612 1.0 3024128 ChemDiv3_004812 CC(C)N1C(=O)S/C(=C/c2cc(Br)c(OCC(=O)O)c(Br)c2)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K17 compound treatment 1017303.0 273000.0 0.58 1074625.0 477000.0 1.08 1.1753 0.9565 3119123 ChemDiv3_004813 CCNS(=O)(=O)c1cc(ccc1C)c2nn(C)c(=O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K18 compound treatment 1271073.0 526000.0 1.12 1412801.0 815000.0 1.85 2.0994 0.9705 3024129 ChemDiv3_004814 CC(CC(=O)O)CC(=O)Nc1cccc(c1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K19 compound treatment 1245067.0 500000.0 1.06 1394479.0 797000.0 1.81 2.031 0.9675 3119124 ChemDiv3_004815 O=C1CS/C(=N\c2ccccc2)/N1S(=O)(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K20 compound treatment 1337786.0 593000.0 1.26 1227412.0 630000.0 1.43 1.9014 0.9979 3024130 ChemDiv3_004816 CN(CCOC(=O)C1c2ccccc2Oc3ccccc13)Cc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K21 compound treatment 1361682.0 617000.0 1.31 1188223.0 591000.0 1.34 1.8742 0.9999 1215426 ChemDiv3_004817 CC(C)CCNc1nnnc2c1sc3nc(N4CCOCC4)c5CCCCc5c32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K22 compound treatment 1450283.0 705000.0 1.5 1187760.0 590000.0 1.34 2.0063 0.9985 3119125 ChemDiv3_004818 Cc1nn(C(=O)CNC(=O)c2ccccc2)c(C)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K23 mock treatment 1235536.0 491000.0 1.04 1009806.0 412000.0 0.94 1.3983 0.9986 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 K24 mock treatment 597221.0 -148000.0 -0.31 452624.0 -145000.0 -0.33 -0.4543 -0.9997 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L01 compound treatment 517180.0 -228000.0 -0.48 573302.0 -24300.0 -0.06 -0.3803 -0.7831 1529468 ChemDiv3_004819 CC(C)Oc1ccc(cc1)C(=O)NC(CC(=O)O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L02 compound treatment 693664.0 -51100.0 -0.11 879182.0 282000.0 0.64 0.376 0.5791 1439481 ChemDiv3_004820 CCOc1ccc(cc1)C2=C(CN3CCOCC3)C(c4ccccc4)c5ccccc5O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L03 compound treatment 974521.0 230000.0 0.49 940660.0 343000.0 0.78 0.8958 0.9743 1562687 ChemDiv3_004821 CC(C)COc1ccc(cc1)C(CC(=O)O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L04 compound treatment 651109.0 -93700.0 -0.2 788801.0 191000.0 0.43 0.1669 0.3493 3119126 ChemDiv3_004822 FC(F)(F)c1oc2cc(OC(=O)c3ccco3)ccc2c(=O)c1c4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L05 compound treatment 921707.0 177000.0 0.38 905899.0 308000.0 0.7 0.7608 0.9571 3119127 ChemDiv3_004823 Cc1ccc2n3CCN(C/C(=N/O)/c4ccc(Br)cc4)C5CCCc(c53)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L06 compound treatment 960843.0 216000.0 0.46 806567.0 209000.0 0.48 0.6598 0.9998 1360838 ChemDiv3_004824 CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)N2CCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L07 compound treatment 1070468.0 326000.0 0.69 1044665.0 447000.0 1.02 1.2069 0.9823 3119128 ChemDiv3_004825 CC/1=NN(C(=O)\C1=C\Nc2ccc(cc2)S(=O)(=O)NC(=N)N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L08 compound treatment 908283.0 163000.0 0.35 838782.0 241000.0 0.55 0.6328 0.9755 3024131 ChemDiv3_004826 Cc1[nH]c2ccccc2c1/C=C/3\SC(=O)N(C3=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L09 compound treatment 100447.0 -644000.0 -1.37 116252.0 -481000.0 -1.09 -1.7398 -0.994 3119129 ChemDiv3_004827 Cc1ccc(NC2=C/C(=N/S(=O)(=O)c3ccc(F)cc3)/c4ccccc4C2=O)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L10 compound treatment 1089351.0 345000.0 0.73 884133.0 286000.0 0.65 0.9771 0.9984 3024132 ChemDiv3_004828 N=c1c(cc2c(=O)n3ccccc3nc2n1Cc4ccco4)S(=O)(=O)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L11 compound treatment 1216624.0 472000.0 1.0 1049582.0 452000.0 1.03 1.4339 0.9999 1694361 ChemDiv3_004829 CCC(C)(C)C1CCc2oc3ccc(NS(=O)(=O)c4cccs4)cc3c2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L12 compound treatment 934334.0 190000.0 0.4 812105.0 214000.0 0.49 0.6289 0.9954 1919128 ChemDiv3_004830 O=C1NN=C(CC1c2c[nH]c3ccccc23)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L13 compound treatment 151201.0 -594000.0 -1.26 154773.0 -443000.0 -1.01 -1.6018 -0.9939 3119254 ChemDiv3_004831 COc1ccc(cc1)C2SCCN2C(=S)Nc3cccc(c3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L14 compound treatment 1314774.0 570000.0 1.21 1096588.0 499000.0 1.13 1.6566 0.9995 3024133 ChemDiv3_004832 COC(=O)C/1=C(C)N(C(=O)\C1=C/c2cccs2)c3ccccc3Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L15 compound treatment 916355.0 172000.0 0.36 944196.0 347000.0 0.79 0.8143 0.9384 1223261 ChemDiv3_004833 CCOc1ccc(NC(=O)CC2N(CCc3ccccc3)C(=S)N(C)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L16 compound treatment 1280658.0 536000.0 1.14 954080.0 356000.0 0.81 1.3763 0.9863 3024134 ChemDiv3_004834 COc1cc2c(cc1NC(=O)CC(C)(C)C)oc3ccccc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L17 compound treatment 1149321.0 405000.0 0.86 934708.0 337000.0 0.77 1.1483 0.9984 1674175 ChemDiv3_004835 O=C(Cn1c2ccccc2c3ccccc13)Sc4nc5ccccc5s4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L18 compound treatment 1226972.0 482000.0 1.02 1085067.0 487000.0 1.11 1.5064 0.9992 3024135 ChemDiv3_004836 COCc1nnc(NS(=O)(=O)c2ccc(OC)cc2)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L19 compound treatment 1482948.0 738000.0 1.56 946689.0 349000.0 0.79 1.6677 0.9505 3024136 ChemDiv3_004837 Cc1cc(C)n(n1)C(=O)c2ccncc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L20 compound treatment 1209694.0 465000.0 0.99 1025519.0 428000.0 0.97 1.3848 1.0 3119255 ChemDiv3_004838 CCN(CC)c1ccc(/C=c/2\sc3ncnn3c2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L21 compound treatment 1113015.0 368000.0 0.78 939669.0 342000.0 0.78 1.1018 1.0 3119256 ChemDiv3_004839 Cc1ccc(cc1)c2nnc(SC3CC(=O)N(C3=O)c4ccccc4)[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L22 compound treatment 1105290.0 361000.0 0.76 832628.0 235000.0 0.53 0.9182 0.9847 1250836 ChemDiv3_004840 CC(Sc1ccccn1)C(=O)Nc2ccc(cc2)S(=O)(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L23 mock treatment 1109311.0 365000.0 0.77 730049.0 132000.0 0.3 0.7593 0.9155 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 L24 mock treatment 650096.0 -94700.0 -0.2 461094.0 -137000.0 -0.31 -0.3615 -0.9777 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M01 compound treatment 649047.0 -95700.0 -0.2 546854.0 -50800.0 -0.12 -0.2252 -0.9643 1870017 ChemDiv3_004841 COc1ccc2c(c1)c(=O)oc3c(C)c4occ(C)c4cc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M02 compound treatment 837365.0 92600.0 0.2 817773.0 220000.0 0.5 0.4927 0.9164 3024137 ChemDiv3_004842 Cc1cccc(c1)n2ncc3c4nc(COc5c(C)cccc5C)nn4cnc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M03 compound treatment 929715.0 185000.0 0.39 962501.0 365000.0 0.83 0.8638 0.9414 3119257 ChemDiv3_004843 COc1ccc(Oc2c(F)c(F)nc(F)c2Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M04 compound treatment 165583.0 -579000.0 -1.23 106496.0 -491000.0 -1.12 -1.6578 -0.9989 1696007 ChemDiv3_004844 CC(C)CCOc1ccc(cc1)C(=O)C(CN2CCOCC2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M05 compound treatment 1141047.0 396000.0 0.84 951720.0 354000.0 0.81 1.1632 0.9998 3024138 ChemDiv3_004845 O=C1c2ccccc2-c3n[nH]c(=O)c4ccc(NC5CCCCC5)c1c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M06 compound treatment 1039800.0 295000.0 0.63 872381.0 275000.0 0.62 0.8839 1.0 3119258 ChemDiv3_004846 N/C(=N\O)/c1cn(CCOc2ccccc2Cl)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M07 compound treatment 1173542.0 429000.0 0.91 917551.0 320000.0 0.73 1.157 0.9939 3024190 ChemDiv3_004847 O=C(Nc1nc2NC(=O)CC(c3ccccc3)n2n1)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M08 compound treatment 1100938.0 356000.0 0.76 943137.0 345000.0 0.79 1.0893 0.9998 3119259 ChemDiv3_004848 Cc1ccc(cc1)S(=O)(=O)/N=C(\NC2CCCCC2)/c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M09 compound treatment 1085853.0 341000.0 0.72 881421.0 284000.0 0.65 0.9675 0.9984 1477219 ChemDiv3_004849 CC(=C)c1cccc(c1)C(C)(C)NC(=O)NCCc2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M10 compound treatment 228964.0 -516000.0 -1.09 256414.0 -341000.0 -0.78 -1.3218 -0.9859 1248399 ChemDiv3_004850 CCC(C)c1ccc(O)c(NC(=O)c2cccnc2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M11 compound treatment 1292582.0 548000.0 1.16 1032640.0 435000.0 0.99 1.5205 0.9968 3119260 ChemDiv3_004851 C=CCNc1nc(Nc2ccc(cc2)c3nc4ccccc4o3)nc(n1)N5CCOCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M12 compound treatment 1210290.0 466000.0 0.99 1001098.0 403000.0 0.92 1.3464 0.9993 3024191 ChemDiv3_004852 CS(=O)(=O)CCC(N1C(=O)c2ccccc2C1=O)C(=O)n3nnc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M13 compound treatment 1011965.0 267000.0 0.57 847011.0 249000.0 0.57 0.8014 1.0 3119261 ChemDiv3_004853 CCC(=O)Nc1ccccc1C(=O)OCC(=O)Nc2ccc(cc2)S(=O)(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M14 compound treatment 1233105.0 488000.0 1.04 922641.0 325000.0 0.74 1.2545 0.9863 1631121 ChemDiv3_004854 O=C(NCCC1=CCCCC1)c2ccc3OCOc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M15 compound treatment 1005812.0 261000.0 0.55 995593.0 398000.0 0.9 1.031 0.9722 3119262 ChemDiv3_004855 CCOc1ccc(cc1)c2nnc(Nc3ccc(OC)cc3)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M16 compound treatment 1038291.0 294000.0 0.62 913999.0 316000.0 0.72 0.9486 0.9974 3119263 ChemDiv3_004856 COC(=O)CN1C(=O)S/C(=C/c2ccc(o2)c3ccc(cc3)C(=O)O)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M17 compound treatment 935324.0 191000.0 0.4 852457.0 255000.0 0.58 0.6953 0.9845 3024192 ChemDiv3_004857 Cc1ccc(OCC(=O)Nc2cc(ccc2N3CCOCC3)c4nn(C)c(=O)c5ccccc45)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M18 compound treatment 1170927.0 426000.0 0.9 953060.0 355000.0 0.81 1.2102 0.9985 3119264 ChemDiv3_004858 CC(C)NC(=O)/C(=N\O)/c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M19 compound treatment 1103308.0 359000.0 0.76 1116679.0 519000.0 1.18 1.3719 0.9774 3119265 ChemDiv3_004859 COC(=O)/C=C/1\S/C(=N\S(=O)(=O)c2ccccc2)/N(C1=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M20 compound treatment 1271453.0 527000.0 1.12 1015776.0 418000.0 0.95 1.4617 0.9968 1222873 ChemDiv3_004860 O=C(Nc1nc2ccccc2s1)C3c4ccccc4Oc5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M21 compound treatment 1303942.0 559000.0 1.19 1044850.0 447000.0 1.02 1.5571 0.9971 3119266 ChemDiv3_004861 C=CCSc1ncnc2c1sc3nc(N4CCOCC4)c5CCCCc5c32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M22 compound treatment 765480.0 20700.0 0.04 672023.0 74400.0 0.17 0.1506 0.862 1867990 ChemDiv3_004862 CC1CC(c2ccccc2)c3cc(C)ccc3N1C(=O)c4ccccc4F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M23 mock treatment 1042190.0 297000.0 0.63 894073.0 296000.0 0.67 0.9224 0.9994 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 M24 mock treatment 619787.0 -125000.0 -0.26 447779.0 -150000.0 -0.34 -0.4283 -0.9923 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N01 compound treatment 514700.0 -230000.0 -0.49 564314.0 -33300.0 -0.08 -0.3985 -0.8073 3024156 ChemDiv3_004863 CCOc1ccc(cc1)C(N)CC(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N02 compound treatment 386507.0 -358000.0 -0.76 440568.0 -157000.0 -0.36 -0.7896 -0.9408 1357341 ChemDiv3_004864 CCOc1ccc(cc1)C2=C(CN(C)C)C(c3ccc(F)cc3)c4ccccc4O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N03 compound treatment 157771.0 -587000.0 -1.24 163228.0 -434000.0 -0.99 -1.5783 -0.9934 1466560 ChemDiv3_004865 CC[N+]1(CC)Cc2cc3ccccc3cc2C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N04 compound treatment 780016.0 35200.0 0.07 850453.0 253000.0 0.57 0.4592 0.7923 3024160 ChemDiv3_004866 CCOc1ccc(/C=C/C(=O)Nc2nc(c(C)s2)c3ccc(C)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N05 compound treatment 622522.0 -122000.0 -0.26 605987.0 8350.0 0.02 -0.1699 -0.6536 3024162 ChemDiv3_004867 CCOC(=O)/C=C/1\CCCCCN1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N06 compound treatment 1206042.0 461000.0 0.98 1000455.0 403000.0 0.92 1.339 0.9995 3119267 ChemDiv3_004868 CCCC1(CC(CSC(=N)N)OC1=O)C(=O)OCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N07 compound treatment 157143.0 -588000.0 -1.25 161808.0 -436000.0 -0.99 -1.5816 -0.9936 3119268 ChemDiv3_004869 Cc1ccc(c(C)c1)S(=O)(=O)/N=C/2\C=CC(=O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N08 compound treatment 1001444.0 257000.0 0.54 946618.0 349000.0 0.79 0.9458 0.9831 3024166 ChemDiv3_004870 CCc1ccc(cc1)N2C(=O)/C(=C/c3cccn3C(C)(C)C)/C(=O)NC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N09 compound treatment 241991.0 -503000.0 -1.07 248165.0 -349000.0 -0.79 -1.3155 -0.9895 1207988 ChemDiv3_004871 CC(C)c1ccc(cc1)S(=O)(=O)Nc2cc(SCC(=O)O)c(O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N10 compound treatment 1123791.0 379000.0 0.8 992282.0 395000.0 0.9 1.2026 0.9985 1875255 ChemDiv3_004872 CCn1c(=N)c(cc2c(=O)n3ccccc3nc12)S(=O)(=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N11 compound treatment 985577.0 241000.0 0.51 930528.0 333000.0 0.76 0.8961 0.9816 1240844 ChemDiv3_004873 Clc1ccc(NC(=O)CSC2CC(=O)N(C2=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N12 compound treatment 1109671.0 365000.0 0.77 968156.0 371000.0 0.84 1.1426 0.9991 3119269 ChemDiv3_004874 CCSC1=N/C(=C\c2cc3OCOc3cc2Br)/C(=O)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N13 compound treatment 1127784.0 383000.0 0.81 820568.0 223000.0 0.51 0.9325 0.9743 3119270 ChemDiv3_004875 CCOC(=O)c1ccc(/N=C/2\SC(CC(=O)N2Cc3cccs3)C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N14 compound treatment 962869.0 218000.0 0.46 849326.0 252000.0 0.57 0.7315 0.9944 3024171 ChemDiv3_004876 FC(F)(F)c1ccc(/C=C\2/NC(=O)N(C2=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N15 compound treatment 988078.0 243000.0 0.52 941858.0 344000.0 0.78 0.9181 0.9795 1264989 ChemDiv3_004877 CN1C(=O)C(CC(=O)Nc2ccc(F)cc2)N(Cc3ccccc3)C1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N16 compound treatment 1040829.0 296000.0 0.63 921491.0 324000.0 0.74 0.9644 0.9968 3024216 ChemDiv3_004878 CC(C)C1Cc2c(CO1)sc3[nH]c(=S)n(Cc4ccccc4)c(=O)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N17 compound treatment 1040799.0 296000.0 0.63 847733.0 250000.0 0.57 0.8458 0.9988 3119271 ChemDiv3_004879 COC(=O)/C=C/1\SC(=NC1=O)NC(=O)c2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N18 compound treatment 1021228.0 276000.0 0.59 865255.0 268000.0 0.61 0.8446 0.9998 3119272 ChemDiv3_004880 CC1CCN(CC1)S(=O)(=O)c2ccc(NC(=O)c3c(C)onc3c4ccccc4Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N19 compound treatment 1083522.0 339000.0 0.72 930203.0 333000.0 0.76 1.0424 0.9997 1733561 ChemDiv3_004881 COc1cc(OC)cc(c1)C(=O)n2nc(C)cc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N20 compound treatment 1177799.0 433000.0 0.92 985141.0 388000.0 0.88 1.2721 0.9998 3024219 ChemDiv3_004882 Cc1ccc(/C=c/2\sc3ncnn3c2=O)o1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N21 compound treatment 1059519.0 315000.0 0.67 999215.0 402000.0 0.91 1.1174 0.9881 3119398 ChemDiv3_004883 CCSc1nc(C)c2cc(OC)ccc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N22 compound treatment 1240233.0 495000.0 1.05 887727.0 290000.0 0.66 1.209 0.9749 3024221 ChemDiv3_004884 CC(Sc1nc(=O)cc(N)n1CC=C)C(=O)Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N23 mock treatment 1113146.0 368000.0 0.78 922872.0 325000.0 0.74 1.075 0.9996 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 N24 mock treatment 605657.0 -139000.0 -0.29 407523.0 -190000.0 -0.43 -0.5142 -0.9826 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O01 compound treatment 536179.0 -209000.0 -0.44 467760.0 -130000.0 -0.3 -0.5215 -0.9807 3119399 ChemDiv3_004885 CCc1cc(=O)oc2cc(C)c3c(coc3c12)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O02 compound treatment 175473.0 -569000.0 -1.21 153959.0 -444000.0 -1.01 -1.5667 -0.996 3119400 ChemDiv3_004886 Cc1cc(NCCN2CCCCC2)c3ccc4ccccc4c3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O03 compound treatment 1185053.0 440000.0 0.93 843299.0 246000.0 0.56 1.0549 0.9699 3024223 ChemDiv3_004887 Fc1nc(N2CCOCC2)c(F)c(Oc3ccc4C(=O)CCC(c5ccccc5)c4c3)c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O04 compound treatment 142483.0 -602000.0 -1.28 132169.0 -465000.0 -1.06 -1.6512 -0.9956 3119401 ChemDiv3_004888 C[n+]1ccc(/C=C/c2ccc3OCOc3c2)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O05 compound treatment 1432534.0 688000.0 1.46 971750.0 374000.0 0.85 1.6324 0.9671 3119402 ChemDiv3_004889 Fc1nc(N2CCOCC2)c3Oc4ccccc4Oc3c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O06 compound treatment 1473343.0 729000.0 1.54 1031170.0 434000.0 0.99 1.7891 0.9765 3024226 ChemDiv3_004890 CN1CCc2c(C1)sc3NC(/C=C/c4ccco4)N=C(O)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O07 compound treatment 1385235.0 640000.0 1.36 988730.0 391000.0 0.89 1.5888 0.9789 3119403 ChemDiv3_004891 O=C1CC(c2ccccc2)n3nc(NS(=O)(=O)c4ccccc4)nc3N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O08 compound treatment 1229203.0 484000.0 1.03 901672.0 304000.0 0.69 1.2149 0.9814 3119404 ChemDiv3_004892 CC(=O)Nc1ccc(NC(=O)[C@@H]2CCCC[C@@H]2C(=O)O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O09 compound treatment 1335984.0 591000.0 1.25 1094100.0 496000.0 1.13 1.6844 0.9986 1275727 ChemDiv3_004893 CC(=C)c1cccc(c1)C(C)(C)NC(=O)NC2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O10 compound treatment 1391622.0 647000.0 1.37 986050.0 388000.0 0.88 1.594 0.9773 3024270 ChemDiv3_004894 CC1Cc2cc(/C=C/3\N=C(OC3=O)c4ccccc4F)ccc2O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O11 compound treatment 1086874.0 342000.0 0.73 820852.0 223000.0 0.51 0.8716 0.9848 3119405 ChemDiv3_004895 COc1ccc(CCNc2nc(Nc3ccc(Cl)cc3)nc(OC)n2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O12 compound treatment 1583775.0 839000.0 1.78 1052259.0 455000.0 1.03 1.9885 0.9667 1378371 ChemDiv3_004896 OC(=O)Cn1c(=O)oc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O13 compound treatment 1438864.0 694000.0 1.47 1006258.0 409000.0 0.93 1.6974 0.9754 3119406 ChemDiv3_004897 CCOC(=O)c1ccc(NC(=O)CSC2=NC(=O)C(CC)C(=O)N2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O14 compound treatment 1412470.0 668000.0 1.42 1090278.0 493000.0 1.12 1.7929 0.9933 3024272 ChemDiv3_004898 CCS(=O)(=O)c1ccc2OC(=O)/C(=C\C(=O)c3oc(C)nc3C)/Nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O15 compound treatment 1124925.0 380000.0 0.81 811062.0 213000.0 0.49 0.9129 0.9705 3119407 ChemDiv3_004899 CCOc1ccc(cc1)c2n[nH]c(=S)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O16 compound treatment 964224.0 219000.0 0.47 784986.0 187000.0 0.43 0.6301 0.999 3119408 ChemDiv3_004900 CC(C)N1C(=O)S/C(=C/c2ccccc2OCc3ccc(cc3)C(=O)O)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O17 compound treatment 1008018.0 263000.0 0.56 858347.0 261000.0 0.59 0.8137 0.9995 3024275 ChemDiv3_004901 CN(C1=NC(=O)/C(=C\c2ccccc2Cl)/S1)c3ccc(O)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O18 compound treatment 1339792.0 595000.0 1.26 1106834.0 509000.0 1.16 1.7105 0.9991 3024277 ChemDiv3_004902 CCNC(=O)/C(=N\O)/c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O19 compound treatment 1454243.0 709000.0 1.5 1199174.0 602000.0 1.37 2.0305 0.9989 3119409 ChemDiv3_004903 CC1N(CCc2c1[nH]c3ccccc23)C(=S)Nc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O20 compound treatment 1229835.0 485000.0 1.03 1028991.0 431000.0 0.98 1.4206 0.9997 3119410 ChemDiv3_004904 O=C(C1c2ccccc2Oc3ccccc13)N4CCC(C4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O21 compound treatment 1349621.0 605000.0 1.28 1237759.0 640000.0 1.46 1.9357 0.998 3024279 ChemDiv3_004905 Cc1nc(SCCOc2ccccc2)sc1C(=O)Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O22 compound treatment 1271523.0 527000.0 1.12 1145399.0 548000.0 1.25 1.6702 0.9985 3119411 ChemDiv3_004906 C1N(N2CN(N1C2)c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O23 mock treatment 1033976.0 289000.0 0.61 872993.0 275000.0 0.63 0.8762 0.9999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 O24 mock treatment 496442.0 -248000.0 -0.53 428062.0 -170000.0 -0.39 -0.6449 -0.9883 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P01 compound treatment 375209.0 -370000.0 -0.78 411251.0 -186000.0 -0.42 -0.8537 -0.9584 1204591 ChemDiv3_004907 NC(=O)c1ccc(cc1)c2nnc(o2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P02 compound treatment 284059.0 -461000.0 -0.98 224019.0 -374000.0 -0.85 -1.2913 -0.9976 3119412 ChemDiv3_004908 CCC(O)C1=C(Oc2ccccc2C1c3ccccc3C)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P03 compound treatment 398057.0 -347000.0 -0.74 413260.0 -184000.0 -0.42 -0.8162 -0.9645 1620080 ChemDiv3_004909 CC[N+](C)(CC)Cc1cc2ccccc2c3COCc31 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P04 compound treatment 520012.0 -225000.0 -0.48 529476.0 -68200.0 -0.15 -0.4465 -0.8911 3119413 ChemDiv3_004910 Clc1ccc(cc1)c2csc3nc[nH]c(=S)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P05 compound treatment 581212.0 -164000.0 -0.35 587015.0 -10600.0 -0.02 -0.2623 -0.7545 3119414 ChemDiv3_004911 CCCCC1(CC)C(=O)NC(=O)N=C1Nc2ccc(OC)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P06 compound treatment 685765.0 -59000.0 -0.13 777032.0 179000.0 0.41 0.1999 0.4686 3119415 ChemDiv3_004912 CCC1CCCCN1S(=O)(=O)c2ccc(NC(=O)COc3ccc(OC)cc3)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P07 compound treatment 242694.0 -502000.0 -1.06 276281.0 -321000.0 -0.73 -1.2693 -0.9831 3024336 ChemDiv3_004913 CCc1ccc(cc1)S(=O)(=O)/N=C/2\C=CC(=O)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P08 compound treatment 459289.0 -286000.0 -0.61 465281.0 -132000.0 -0.3 -0.6408 -0.948 3119416 ChemDiv3_004914 COC(=O)CN1C(=O)S/C(=C/c2cn(CC=C)c3ccccc23)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P09 compound treatment 575018.0 -170000.0 -0.36 597566.0 -74.4 0.0 -0.2546 -0.7074 1330391 ChemDiv3_004915 O=C(N(c1ccc2oc3CCCCc3c2c1)S(=O)(=O)c4ccccc4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P10 compound treatment 681009.0 -63800.0 -0.14 590443.0 -7200.0 -0.02 -0.1072 -0.7869 3119417 ChemDiv3_004916 N=c1c(cc2c(=O)n3ccccc3nc2n1C4CCCC4)S(=O)(=O)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P11 compound treatment 583507.0 -161000.0 -0.34 483014.0 -115000.0 -0.26 -0.426 -0.991 1651800 ChemDiv3_004917 CC(=O)N(CCc1ccccc1)C2CC(=O)N(C2=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P12 compound treatment 620381.0 -124000.0 -0.26 456531.0 -141000.0 -0.32 -0.4133 -0.9953 3024341 ChemDiv3_004918 CCSC1=N/C(=C\c2ccc(Br)s2)/C(=O)S1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P13 compound treatment 621852.0 -123000.0 -0.26 472837.0 -125000.0 -0.28 -0.3849 -0.9991 3119418 ChemDiv3_004919 CNC(=O)CC1N(NC(=O)c2cccc(F)c2)C(=S)N(C1=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P14 compound treatment 721806.0 -23000.0 -0.05 504779.0 -92900.0 -0.21 -0.1837 -0.848 3024342 ChemDiv3_004920 COc1cccc(/C=C\2/NC(=O)N(C2=O)c3ccccc3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P15 compound treatment 629917.0 -115000.0 -0.24 554818.0 -42800.0 -0.1 -0.241 -0.9191 1153500 ChemDiv3_004921 CC1CC(Nc2ccccc2)c3ccccc3N1C(=O)c4ccncc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P16 compound treatment 707201.0 -37600.0 -0.08 668418.0 70800.0 0.16 0.0574 0.3199 3024345 ChemDiv3_004922 CCOC(=O)c1c(NC(=S)Nc2ccc(OC)cc2)sc3COC(Cc13)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P17 compound treatment 644015.0 -101000.0 -0.21 580598.0 -17000.0 -0.04 -0.1785 -0.8219 3119419 ChemDiv3_004923 COC(=O)/C=C/1\SC(=NC1=O)NC(=O)c2ccc(OC)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P18 compound treatment 686170.0 -58600.0 -0.12 639203.0 41600.0 0.09 -0.0211 -0.1349 3119420 ChemDiv3_004924 CC(C)c1nnc(NC(=O)C2c3ccccc3Oc4ccccc24)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P19 compound treatment 717324.0 -27500.0 -0.06 630690.0 33000.0 0.08 0.012 0.1258 3024347 ChemDiv3_004925 CC1=CC(C)(C)N(C(=O)Nc2ccc(C)cc2)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P20 compound treatment 765852.0 21100.0 0.04 622105.0 24500.0 0.06 0.0709 0.9941 3119421 ChemDiv3_004926 CCc1ccc(/C=c/2\sc3nc(nn3c2=O)C4COc5ccccc5O4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P21 compound treatment 664350.0 -80400.0 -0.17 589005.0 -8640.0 -0.02 -0.1345 -0.7833 1871084 ChemDiv3_004927 CC(N1C(=O)c2ccccc2C1=O)C(=O)N3CCN(CC3)c4ccc(F)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P22 compound treatment 620450.0 -124000.0 -0.26 529629.0 -68000.0 -0.15 -0.2957 -0.9677 3119422 ChemDiv3_004928 CCc1ccc(NC2SC(=O)N(C2=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P23 mock treatment 510920.0 -234000.0 -0.5 513126.0 -84500.0 -0.19 -0.4864 -0.9148 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2014 P24 mock treatment 427842.0 -317000.0 -0.67 387577.0 -210000.0 -0.48 -0.8128 -0.986 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A01 compound treatment 416916.0 -263000.0 -0.56 349265.0 -345000.0 -0.78 -0.9484 -0.986 3119423 ChemDiv3_004929 COc1cc(cc(OC)c1OC)C(=O)/C=C/Nc2ccc(cc2)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A02 compound treatment 487592.0 -192000.0 -0.41 420532.0 -274000.0 -0.62 -0.7279 -0.979 3024419 ChemDiv3_004930 OC(=O)c1ccc(NC(=O)CCCN2C(=O)S/C(=C\C=C\c3ccccc3)/C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A03 compound treatment 595192.0 -84600.0 -0.18 486199.0 -208000.0 -0.47 -0.461 -0.9119 3119424 ChemDiv3_004931 Cc1ccc(cc1C)n2nc(C(=O)O)c(C)c(C#N)c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A04 compound treatment 440560.0 -239000.0 -0.51 392505.0 -302000.0 -0.69 -0.8434 -0.989 3119563 ChemDiv3_004932 CC1(C)C2CCC1(C)C(C2)NCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A05 compound treatment 519822.0 -160000.0 -0.34 446180.0 -248000.0 -0.56 -0.6383 -0.9704 3024422 ChemDiv3_004933 COc1ccc2-c3nc(/N=C/c4ccc(C)cc4)sc3CCc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A06 compound treatment 155420.0 -524000.0 -1.11 155031.0 -539000.0 -1.23 -1.6527 -0.9988 3119564 ChemDiv3_004934 COc1ccc(cc1)C2NC(C(C)C(O)(Cc3ccccc3)C2C)c4ccc(OC)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A07 compound treatment 321157.0 -359000.0 -0.76 363899.0 -330000.0 -0.75 -1.0684 -1.0 3024425 ChemDiv3_004935 CC1(C)COC(=N1)Nc2cccc(Cl)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A08 compound treatment 571436.0 -108000.0 -0.23 435356.0 -259000.0 -0.59 -0.5784 -0.9159 1195009 ChemDiv3_004936 COc1ccc(cc1)c2cc(=O)c3cc(OC(=O)c4ccc(OC)c(OC)c4)ccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A09 compound treatment 477521.0 -202000.0 -0.43 444495.0 -250000.0 -0.57 -0.7045 -0.9904 3024428 ChemDiv3_004937 CC(C)(C)C(=O)NC(=S)Nc1ccc2C(=O)OCc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A10 compound treatment 439185.0 -241000.0 -0.51 424918.0 -269000.0 -0.61 -0.7934 -0.9959 3119565 ChemDiv3_004938 CCOC(=O)c1cnc2c(cccc2c1N3CCN(C)CC3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A11 compound treatment 425419.0 -254000.0 -0.54 401080.0 -293000.0 -0.67 -0.8524 -0.9945 3024430 ChemDiv3_004939 CCOc1ccc(/C=C/2\N(CC(=O)OC)C(=S)N(C)C2=O)c(OCC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A12 compound treatment 196073.0 -484000.0 -1.03 183178.0 -511000.0 -1.16 -1.5465 -0.9981 3119566 ChemDiv3_004940 COC(=O)c1sc(c(C(=O)OC)c1C)S(=O)(=O)NC2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A13 compound treatment 495985.0 -184000.0 -0.39 669180.0 -24900.0 -0.06 -0.3156 -0.8015 3024433 ChemDiv3_004941 COC(=O)c1cc2c(=O)n3ccccc3nc2n(C(C)C)c1=N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A14 compound treatment 236091.0 -444000.0 -0.94 217302.0 -477000.0 -1.08 -1.4316 -0.9975 3119567 ChemDiv3_004942 COc1cc(/C=C/C(=O)\C=C\c2ccc(cc2)N(C)C)cc(OC)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A15 compound treatment 551530.0 -128000.0 -0.27 687774.0 -6320.0 -0.01 -0.2024 -0.7434 1280049 ChemDiv3_004943 CC1(C)CC(=O)C(C(=S)Nc2ccccc2)C(=O)C1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A16 compound treatment 492118.0 -188000.0 -0.4 634851.0 -59200.0 -0.13 -0.3766 -0.8965 3119568 ChemDiv3_004944 S=C1NCN(Cc2ccccc2)CN1CC3CCCO3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A17 compound treatment 487269.0 -193000.0 -0.41 563877.0 -130000.0 -0.3 -0.4979 -0.9876 1874490 ChemDiv3_004945 CCC1(C)CC(CCN2C(=O)c3ccccc3C2=O)(CCO1)c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A18 compound treatment 488777.0 -191000.0 -0.4 565505.0 -129000.0 -0.29 -0.493 -0.9872 3119569 ChemDiv3_004946 Cc1sc2ncnc(Oc3cccc(c3)C(F)(F)F)c2c1c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A19 compound treatment 547502.0 -132000.0 -0.28 668036.0 -26100.0 -0.06 -0.2402 -0.838 1524496 ChemDiv3_004947 NC(=O)NC(=O)CC1Nc2ccccc2NC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A20 compound treatment 530962.0 -149000.0 -0.32 681987.0 -12100.0 -0.03 -0.2425 -0.7659 1242544 ChemDiv3_004948 OC(=O)c1ccc(Nc2nccc(Nc3ccccc3C(=O)O)n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A21 compound treatment 407966.0 -272000.0 -0.58 497872.0 -196000.0 -0.45 -0.7229 -0.992 3024507 ChemDiv3_004949 CN(C)c1ccc(/C=C\2/N(C(=O)C)c3ccccc3C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A22 compound treatment 474191.0 -206000.0 -0.44 559646.0 -134000.0 -0.31 -0.5243 -0.9849 3119570 ChemDiv3_004950 C=CCNC(=N)SCc1nc2ccccc2c(=O)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A23 mock treatment 473428.0 -206000.0 -0.44 518052.0 -176000.0 -0.4 -0.5923 -0.999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 A24 mock treatment 410330.0 -269000.0 -0.57 419421.0 -275000.0 -0.62 -0.8455 -0.999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B01 compound treatment 377087.0 -303000.0 -0.64 359185.0 -335000.0 -0.76 -0.9922 -0.9964 3119571 ChemDiv3_004951 CCOC(=O)C1CCN(CC1)C(=C2C(=O)c3ccccc3C2=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B02 compound treatment 655934.0 -23800.0 -0.05 452288.0 -242000.0 -0.55 -0.4245 -0.7689 3024512 ChemDiv3_004952 CCc1ccc(/C=C/2\N(C)C(=S)N(C3CCCCC3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B03 compound treatment 349342.0 -330000.0 -0.7 352666.0 -341000.0 -0.78 -1.0442 -0.9987 1481254 ChemDiv3_004953 CCOc1ccc2C(=CC(C)(C)[N+](C)(C)c2c1)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B04 compound treatment 676192.0 -3590.0 -0.01 627596.0 -66500.0 -0.15 -0.1123 -0.7417 1385231 ChemDiv3_004954 Cc1nn(S(=O)c2ccc3ccccc3c2)c(C)c1Sc4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B05 compound treatment 823585.0 144000.0 0.3 861198.0 167000.0 0.38 0.4842 0.994 1871664 ChemDiv3_004955 Clc1nc(nc(n1)N2CCCc3ccccc23)N4CCCc5ccccc45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B06 compound treatment 859983.0 180000.0 0.38 861624.0 168000.0 0.38 0.5395 1.0 3119572 ChemDiv3_004956 COc1ccc(NC(=O)CSc2nc(O)cc(=O)n2c3ccccc3OC)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B07 compound treatment 427298.0 -252000.0 -0.54 410675.0 -283000.0 -0.64 -0.8341 -0.9957 3024517 ChemDiv3_004957 CCOC(=O)C1=C(C)N=C2C(C1c3ccc(Br)cc3)C(=O)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B08 compound treatment 756446.0 76700.0 0.16 725422.0 31300.0 0.07 0.1653 0.9315 3119573 ChemDiv3_004958 CCc1ccc2N(C)C(=O)C(NC(=O)C)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B09 compound treatment 576647.0 -103000.0 -0.22 544057.0 -150000.0 -0.34 -0.3958 -0.9769 3119574 ChemDiv3_004959 COC(=O)C/1=C(C)N(C(=O)\C1=C/c2cc(C)n(c2C)c3ccc(F)cc3)c4ccc(OC)c(OC)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B10 compound treatment 499962.0 -180000.0 -0.38 492009.0 -202000.0 -0.46 -0.5944 -0.9957 3024588 ChemDiv3_004960 CC(C)(C)c1cc(cc(c1)C(C)(C)C)C(=O)OCCN2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B11 compound treatment 915914.0 236000.0 0.5 987414.0 293000.0 0.67 0.8255 0.99 3024591 ChemDiv3_004961 Fc1cc(/C=C\2/NC(=O)NC2=O)ccc1N3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B12 compound treatment 948957.0 269000.0 0.57 900424.0 206000.0 0.47 0.7352 0.9953 3119575 ChemDiv3_004962 CN1C(=O)c2ccc(cc2C1=O)c3nc4ccc(Cl)cc4c(=O)o3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B13 compound treatment 1811064.0 1130000.0 2.4 1588860.0 895000.0 2.03 3.1343 0.9966 3024594 ChemDiv3_004963 CCOc1cc2OCOc2cc1/C=C\3/NC(=O)N(Cc4ccccc4)C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B14 compound treatment 877338.0 198000.0 0.42 811351.0 117000.0 0.27 0.4847 0.9762 3119576 ChemDiv3_004964 CCOc1cc2OCOc2cc1/C=C(\C#N)/c3ccc(cc3)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B15 compound treatment 651556.0 -28200.0 -0.06 633737.0 -60400.0 -0.14 -0.1393 -0.9308 1217444 ChemDiv3_004965 COc1ccc(NCN2C(=O)CCC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B16 compound treatment 816596.0 137000.0 0.29 869786.0 176000.0 0.4 0.4875 0.9876 3119577 ChemDiv3_004966 CCOC(=O)c1nc(NCc2ccccc2)c3ccccc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B17 compound treatment 726203.0 46400.0 0.1 702617.0 8520.0 0.02 0.0833 0.8304 1165861 ChemDiv3_004967 Fc1ccc(NC(=O)Nc2ccc3COC(=O)c3c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B18 compound treatment 769943.0 90200.0 0.19 871258.0 177000.0 0.4 0.42 0.942 3024598 ChemDiv3_004968 CC(C)(C)C(=O)C(=C1Nc2ccccc2N1)C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B19 compound treatment 699129.0 19300.0 0.04 656158.0 -37900.0 -0.09 -0.032 -0.3349 3024601 ChemDiv3_004969 CC(C)Cn1c(S)nc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B20 compound treatment 904764.0 225000.0 0.48 856497.0 162000.0 0.37 0.5983 0.992 3119578 ChemDiv3_004970 OC(=O)CCc1ccc(c2ccccc2)n1c3cccc(O)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B21 compound treatment 781165.0 101000.0 0.21 736436.0 42300.0 0.1 0.22 0.9344 3119579 ChemDiv3_004971 Clc1cccc(Cc2cn3cc(nc3s2)c4ccccc4)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B22 compound treatment 845542.0 166000.0 0.35 934735.0 241000.0 0.55 0.6353 0.9771 3024603 ChemDiv3_004972 NC(=O)CSc1ccc2ccccc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B23 mock treatment 809842.0 130000.0 0.28 803204.0 109000.0 0.25 0.3704 0.9986 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 B24 mock treatment 434670.0 -245000.0 -0.52 468042.0 -226000.0 -0.51 -0.7308 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C01 compound treatment 538221.0 -142000.0 -0.3 509084.0 -185000.0 -0.42 -0.5096 -0.9863 3119580 ChemDiv3_004973 COc1cc(cc(OC)c1OC)C(=O)/C=C/Nc2ccccc2C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C02 compound treatment 601113.0 -78700.0 -0.17 537989.0 -156000.0 -0.35 -0.3689 -0.9407 3024606 ChemDiv3_004974 Cc1ccc(NC(=O)/C=C\2/SC(=O)N(CN3CCCCC3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C03 compound treatment 818895.0 139000.0 0.29 711557.0 17500.0 0.04 0.2366 0.7951 1251629 ChemDiv3_004975 COc1ccc(cc1)c2cc3nc(C)cc(C)n3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C04 compound treatment 775741.0 96000.0 0.2 702277.0 8180.0 0.02 0.157 0.7686 3024954 ChemDiv3_004976 CC(NC(CC(=C)C)c1ccco1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C05 compound treatment 728773.0 49000.0 0.1 744322.0 50200.0 0.11 0.1542 0.9989 3119581 ChemDiv3_004977 O=C(Nc1ccccc1)C2CCN(CC2)S(=O)(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C06 compound treatment 759422.0 79600.0 0.17 735132.0 41000.0 0.09 0.1854 0.9609 1157212 ChemDiv3_004978 COc1ccccc1NC(=O)CN2c3cccc4cccc(c34)S2(=O)=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C07 compound treatment 823976.0 144000.0 0.31 845538.0 151000.0 0.34 0.4596 0.9982 3119582 ChemDiv3_004979 Cc1cc(C)nc(NC(=O)CSC(=S)N2CCOCC2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C08 compound treatment 1694223.0 1010000.0 2.15 1795094.0 1100000.0 2.5 3.2907 0.9971 3119583 ChemDiv3_004980 COc1ccc(cc1)c2c/c(=N\C(CC(C)C)C(=O)O)/c3cc(C)ccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C09 compound treatment 786660.0 107000.0 0.23 776089.0 82000.0 0.19 0.292 0.9953 3024959 ChemDiv3_004981 O=C(COn1c(=O)n(COC(=O)c2ccccc2)c3ccccc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C10 compound treatment 738926.0 59100.0 0.13 636059.0 -58000.0 -0.13 -0.0046 -0.0255 1641003 ChemDiv3_004982 CCOC(=O)c1cnc2ccc(Cl)cc2c1Nc3ccc(cc3)S(=O)(=O)Nc4ncccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C11 compound treatment 705512.0 25700.0 0.05 719050.0 25000.0 0.06 0.0787 0.9998 3024961 ChemDiv3_004983 COC(=O)CN/1C(=S)N(C)C(=O)\C1=C\c2ccc(o2)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C12 compound treatment 827297.0 148000.0 0.31 787378.0 93300.0 0.21 0.3711 0.9821 3119584 ChemDiv3_004984 COC(=O)c1sc(c(C(=O)OC)c1C)S(=O)(=O)N2CCN(CC2)c3ccccc3OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C13 compound treatment 2586426.0 1910000.0 4.04 2641969.0 1950000.0 4.43 5.9896 0.999 3024114 ChemDiv3_004985 CCNC(=O)c1cc2c(=O)n3ccccc3nc2n(C(C)C)c1=N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C14 compound treatment 909850.0 230000.0 0.49 829221.0 135000.0 0.31 0.5621 0.9752 3119715 ChemDiv3_004986 CN(C)c1ccc(/C=C/C(=O)\C=C\c2ccc3OCOc3c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C15 compound treatment 899105.0 219000.0 0.46 809710.0 116000.0 0.26 0.5146 0.9635 3024117 ChemDiv3_004987 CN(C)c1nc(nc(n1)N(CC=C)C#N)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C16 compound treatment 555450.0 -124000.0 -0.26 501919.0 -192000.0 -0.44 -0.4953 -0.9707 3119716 ChemDiv3_004988 S=C1NCN(Cc2ccccc2)CN1Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C17 compound treatment 746847.0 67100.0 0.14 896703.0 203000.0 0.46 0.4263 0.8842 1723905 ChemDiv3_004989 COc1ccc(CN(CCC(c2ccco2)c3ccccc3)C(=O)C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C18 compound treatment 643546.0 -36200.0 -0.08 695076.0 980.0 0.0 -0.0527 -0.6863 3024121 ChemDiv3_004990 CC(C)C1N(CCCN1S(=O)(=O)c2ccc(C)cc2)/C(=N/S(=O)(=O)c3ccc(C)cc3)/C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C19 compound treatment 785822.0 106000.0 0.22 787449.0 93400.0 0.21 0.309 0.9996 3119717 ChemDiv3_004991 O=S(=O)(C1c2ccccc2Oc3ccccc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C20 compound treatment 931820.0 252000.0 0.53 850491.0 156000.0 0.36 0.6292 0.9804 1300285 ChemDiv3_004992 CC(Sc1cc(C)c2ccccc2n1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C21 compound treatment 870562.0 191000.0 0.4 814220.0 120000.0 0.27 0.4791 0.9817 3119718 ChemDiv3_004993 Clc1cccc(N/C=C/2\C(=O)Nc3ccccc23)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C22 compound treatment 888846.0 209000.0 0.44 802621.0 109000.0 0.25 0.4879 0.9618 3119719 ChemDiv3_004994 COC(=O)Cc1nn(c(O)c1/C=N/c2ccc(C)cc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C23 mock treatment 779454.0 99700.0 0.21 769598.0 75500.0 0.17 0.2708 0.9947 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 C24 mock treatment 524829.0 -155000.0 -0.33 545218.0 -149000.0 -0.34 -0.4716 -0.9999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D01 compound treatment 410474.0 -269000.0 -0.57 473553.0 -221000.0 -0.5 -0.7583 -0.9979 3024125 ChemDiv3_004995 CC(=C1C(=O)c2ccccc2C1=O)NCc3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D02 compound treatment 541147.0 -139000.0 -0.29 626225.0 -67900.0 -0.15 -0.3169 -0.9548 3024172 ChemDiv3_004996 CN/1C(=S)N(C2CCCCC2)C(=O)\C1=C\c3cc(C)n(c3C)c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D03 compound treatment 580051.0 -99700.0 -0.21 681994.0 -12100.0 -0.03 -0.169 -0.7924 1532710 ChemDiv3_004997 Cc1ccnc(SCC(=O)N2CCc3ccccc3C2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D04 compound treatment 668146.0 -11600.0 -0.02 651965.0 -42100.0 -0.1 -0.0852 -0.8611 3024176 ChemDiv3_004998 Cc1nn(C(=O)c2cc3CCCCc3s2)c(C)c1Sc4ccc(Br)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D05 compound treatment 717400.0 37600.0 0.08 659843.0 -34300.0 -0.08 0.0013 0.0119 1871526 ChemDiv3_004999 Nc1nc(CSC(=S)N2CCCCC2)nc(Nc3ccccc3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D06 compound treatment 768877.0 89100.0 0.19 708038.0 13900.0 0.03 0.156 0.8144 3119720 ChemDiv3_005000 CCOc1ccccc1n2c(SCC(=O)c3ccc4OCCOc4c3)nc(O)cc2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D07 compound treatment 703645.0 23900.0 0.05 707351.0 13300.0 0.03 0.0571 0.9694 3024181 ChemDiv3_005001 Clc1cccc(c1)C2C3C(=O)c4ccccc4C3=NC5=C2C(=O)CCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D08 compound treatment 682350.0 2570.0 0.01 745060.0 51000.0 0.12 0.0858 0.7396 3119721 ChemDiv3_005002 COC(=O)Nc1c(C)nc2n(C)c3ccccc3n12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D09 compound treatment 778431.0 98700.0 0.21 738110.0 44000.0 0.1 0.2186 0.9431 3119722 ChemDiv3_005003 CC/1=NN(C(=O)\C1=C\c2ccc3n(C)c(=O)n(C)c3c2)c4ccc(C)c(C)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D10 compound treatment 841966.0 162000.0 0.34 826306.0 132000.0 0.3 0.4557 0.9978 3024186 ChemDiv3_005004 Clc1ccccc1C(=O)NCCCn2ccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D11 compound treatment 760331.0 80600.0 0.17 818655.0 125000.0 0.28 0.321 0.9707 3119723 ChemDiv3_005005 Cc1cc(/C=C\2/NC(=O)N(Cc3ccccc3F)C2=O)c(C)n1c4ccc(cc4)S(=O)(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D12 compound treatment 841556.0 162000.0 0.34 803758.0 110000.0 0.25 0.4188 0.9877 1402147 ChemDiv3_005006 Cc1c(C)c2ccccc2n1CCc3ccc(C)nc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D13 compound treatment 680429.0 650.0 0.0 802739.0 109000.0 0.25 0.1756 0.711 3024189 ChemDiv3_005007 CN1C(=O)/C(=C/c2ccc(Cl)cc2)/N(C)C1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D14 compound treatment 904607.0 225000.0 0.48 945652.0 252000.0 0.57 0.7414 0.9959 3024228 ChemDiv3_005008 Cc1nc2ncnn2c(O)c1NS(=O)(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D15 compound treatment 812870.0 133000.0 0.28 922524.0 228000.0 0.52 0.5667 0.9589 3119724 ChemDiv3_005009 COc1ccc(cc1)N(C2CC(=O)N(C2=O)c3ccc(OC)cc3)C(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D16 compound treatment 926161.0 246000.0 0.52 953637.0 260000.0 0.59 0.7866 0.9981 3024235 ChemDiv3_005010 CCOC(=O)c1nc(Nc2cccc(C)c2C)c3ccccc3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D17 compound treatment 854077.0 174000.0 0.37 916935.0 223000.0 0.51 0.6195 0.988 1305881 ChemDiv3_005011 COc1ccc(NC(=O)Nc2ccc3COC(=O)c3c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D18 compound treatment 100636.0 -579000.0 -1.23 126434.0 -568000.0 -1.29 -1.7808 -0.9997 3119725 ChemDiv3_005012 CCc1ccc(Oc2c(oc3c(CN4CCCCC4)c(O)ccc3c2=O)C(F)(F)F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D19 compound treatment 786905.0 107000.0 0.23 899715.0 206000.0 0.47 0.4911 0.945 3024238 ChemDiv3_005013 CCn1c(S)nc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D20 compound treatment 116742.0 -563000.0 -1.19 164125.0 -530000.0 -1.2 -1.696 -1.0 1388420 ChemDiv3_005014 COC(=O)c1ccc(cc1)C2Nc3cccc4cccc(N2)c34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D21 compound treatment 998444.0 319000.0 0.68 1027047.0 333000.0 0.76 1.013 0.9984 1523877 ChemDiv3_005015 CC(C)c1nc2ccccc2n1C(=O)c3ccccc3C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D22 compound treatment 717552.0 37800.0 0.08 881064.0 187000.0 0.43 0.3572 0.8258 3024241 ChemDiv3_005016 Cc1noc(C)c1CSc2ccc3ccccc3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D23 mock treatment 809796.0 130000.0 0.28 910702.0 217000.0 0.49 0.5431 0.9624 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 D24 mock treatment 553317.0 -126000.0 -0.27 560960.0 -133000.0 -0.3 -0.4036 -0.9982 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E01 compound treatment 358697.0 -321000.0 -0.68 371065.0 -323000.0 -0.73 -1.0006 -0.9993 3119726 ChemDiv3_005017 CCc1ccc(cc1)C(=O)/C=C/Nc2ccc(C)cc2O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E02 compound treatment 649709.0 -30100.0 -0.06 525520.0 -169000.0 -0.38 -0.3161 -0.8135 3024284 ChemDiv3_005018 COc1ccc(/C=C\2/SC(=O)N(CC(=O)NCCO)C2=O)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E03 compound treatment 677093.0 -2690.0 -0.01 741491.0 47400.0 0.11 0.0722 0.6688 3119727 ChemDiv3_005019 Cc1cc(c2ccccc2)n3ncc(c4ccccc4)c3n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E04 compound treatment 832169.0 152000.0 0.32 834668.0 141000.0 0.32 0.4544 1.0 3024286 ChemDiv3_005020 CC(=O)N1c2c(ccc3ccccc23)C(=CC1(C)C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E05 compound treatment 756915.0 77100.0 0.16 808256.0 114000.0 0.26 0.2992 0.9752 3119728 ChemDiv3_005021 O=C(NCc1ccccc1)C2CCN(CC2)C(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E06 compound treatment 847499.0 168000.0 0.36 828169.0 134000.0 0.3 0.467 0.9971 3119729 ChemDiv3_005022 COC(=O)c1ccc(Oc2nc(Nc3cccc(C)c3C)nc(n2)N4CCC(C)CC4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E07 compound treatment 769535.0 89800.0 0.19 748177.0 54100.0 0.12 0.2215 0.9777 3024291 ChemDiv3_005023 COc1ccc(NCC(=O)n2c3ccccc3c4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E08 compound treatment 2443253.0 1760000.0 3.74 2342219.0 1650000.0 3.75 5.2931 1.0 3119730 ChemDiv3_005024 CCC(/N=c/1\cc(oc2ccc(C)cc12)c3ccc(OC)cc3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E09 compound treatment 868283.0 189000.0 0.4 767559.0 73500.0 0.17 0.4007 0.9251 3024295 ChemDiv3_005025 CCN1C(=O)/C(=N/O)/N(CC)C1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E10 compound treatment 785450.0 106000.0 0.22 824233.0 130000.0 0.3 0.3676 0.9906 1702577 ChemDiv3_005026 CCOC(=O)c1cnc2c(C)cc(C)cc2c1Nc3ccc(cc3)S(=O)(=O)Nc4ncccn4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E11 compound treatment 909948.0 230000.0 0.49 936893.0 243000.0 0.55 0.7354 0.9981 3024297 ChemDiv3_005027 COC(=O)CN/1C(=S)N(C(=O)\C1=C\c2ccc(o2)c3ccc(Cl)cc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E12 compound treatment 994338.0 315000.0 0.67 816543.0 122000.0 0.28 0.6684 0.9249 3024299 ChemDiv3_005028 Clc1ccccc1CSc2nc(=O)cc[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E13 compound treatment 1546485.0 867000.0 1.84 1609474.0 915000.0 2.08 2.7708 0.9981 3119731 ChemDiv3_005029 CC(C)n1c(=N)c(cc2c(=O)n3cccc(C)c3nc12)C(=O)NCCN4CCOCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E14 compound treatment 846663.0 167000.0 0.35 922499.0 228000.0 0.52 0.6174 0.9825 3119732 ChemDiv3_005030 COc1ccc(/C=C/2\CCc3ccccc3C2=O)cc1COc4ccc(F)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E15 compound treatment 935166.0 255000.0 0.54 906818.0 213000.0 0.48 0.7248 0.9984 3024306 ChemDiv3_005031 CC(C)CCSc1nc(N)c2c(C)c(C)sc2n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E16 compound treatment 858455.0 179000.0 0.38 967702.0 274000.0 0.62 0.7077 0.9717 3119733 ChemDiv3_005032 Cc1cccc(c1)N2CN(Cc3ccco3)CNC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E17 compound treatment 919770.0 240000.0 0.51 1028879.0 335000.0 0.76 0.898 0.9808 3024308 ChemDiv3_005033 Cc1ccc(cc1)C(CC(=O)O)c2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E18 compound treatment 830380.0 151000.0 0.32 966183.0 272000.0 0.62 0.6632 0.9527 3119734 ChemDiv3_005034 Cc1nnc(s1)N2C(=N)S/C(=C\c3ccccc3Cl)/C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E19 compound treatment 130759.0 -549000.0 -1.16 130699.0 -563000.0 -1.28 -1.7287 -0.9989 3024312 ChemDiv3_005035 Clc1ccc(N/C=C/2\Nc3ccccc3C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E20 compound treatment 245303.0 -434000.0 -0.92 270346.0 -424000.0 -0.96 -1.3325 -0.9997 3119735 ChemDiv3_005036 Cc1cc(OCC[N+]2(C)CCCCC2)nc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E21 compound treatment 967522.0 288000.0 0.61 1052198.0 358000.0 0.81 1.007 0.9899 3024315 ChemDiv3_005037 CC(C)N/C=C/1\C(=O)Nc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E22 compound treatment 759243.0 79500.0 0.17 1017123.0 323000.0 0.73 0.6384 0.8473 3119736 ChemDiv3_005038 COC(=O)CC/1=NN(C(=O)\C1=C\Nc2ccc(C)cc2)c3nc4ccccc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E23 mock treatment 701178.0 21400.0 0.05 674945.0 -19200.0 -0.04 0.0013 0.0205 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 E24 mock treatment 341676.0 -338000.0 -0.72 377691.0 -316000.0 -0.72 -1.0155 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F01 compound treatment 497880.0 -182000.0 -0.39 515002.0 -179000.0 -0.41 -0.5606 -0.9996 3025240 ChemDiv3_005039 Sc1nnc(c2ccncc2)n1C3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F02 compound treatment 422793.0 -257000.0 -0.54 522606.0 -171000.0 -0.39 -0.6609 -0.9865 3025241 ChemDiv3_005040 CCc1ccc(/C=C/2\NC(=S)N(C3CCCCC3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F03 compound treatment 616632.0 -63100.0 -0.13 615718.0 -78400.0 -0.18 -0.2207 -0.9901 1185203 ChemDiv3_005041 COc1ccc(CC(=O)N2c3ccccc3Sc4ccccc24)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F04 compound treatment 649898.0 -29900.0 -0.06 730033.0 35900.0 0.08 0.013 0.1256 3025242 ChemDiv3_005042 Cc1nn(CO)c(C)c1Sc2ccc(Br)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F05 compound treatment 691333.0 11600.0 0.02 707447.0 13400.0 0.03 0.0388 0.9943 3025243 ChemDiv3_005043 CCN(CC)C(=S)SCc1nc(N)nc(Nc2ccccc2)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F06 compound treatment 769746.0 90000.0 0.19 629300.0 -64800.0 -0.15 0.0307 0.1274 3025244 ChemDiv3_005044 Cc1oc2cc(Br)c(O)c(Br)c2c1c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F07 compound treatment 638555.0 -41200.0 -0.09 563576.0 -131000.0 -0.3 -0.2716 -0.8781 1429843 ChemDiv3_005045 COc1ccc(cc1)C(=O)OC2=C(C(=O)c3ccccc3C2=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F08 compound treatment 1267862.0 588000.0 1.25 1131234.0 437000.0 0.99 1.5843 0.9937 3119737 ChemDiv3_005046 COc1ccc(cc1)n2nc3ccc(NC(=O)CSc4ccc(Cl)cc4)cc3n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F09 compound treatment 919172.0 239000.0 0.51 826767.0 133000.0 0.3 0.5721 0.9691 3025245 ChemDiv3_005047 Cn1nc(c2ccc(N3CCCCC3)c(NC(=O)c4ccccc4)c2)c5ccccc5c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F10 compound treatment 813774.0 134000.0 0.28 929576.0 235000.0 0.54 0.5794 0.956 3119738 ChemDiv3_005048 CCOC(=O)C1C(C2CCOC2=O)c3c(OC1=O)ccc4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F11 compound treatment 981089.0 301000.0 0.64 900718.0 207000.0 0.47 0.7838 0.9886 3025246 ChemDiv3_005049 Clc1cccc(c1)N2C(=O)N/C(=C/c3ccccc3)/C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F12 compound treatment 789239.0 109000.0 0.23 751785.0 57700.0 0.13 0.2568 0.9635 1483558 ChemDiv3_005050 Brc1cccc2C(CC=C)NCCc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F13 compound treatment 889514.0 210000.0 0.44 874126.0 180000.0 0.41 0.6038 0.9991 1345308 ChemDiv3_005051 CCOC(=O)c1sc(NN)nc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F14 compound treatment 1043825.0 364000.0 0.77 934913.0 241000.0 0.55 0.9329 0.9859 3119883 ChemDiv3_005052 FC(F)(F)c1cc(nc(SCC(=O)N2CCCCC2)c1C#N)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F15 compound treatment 992734.0 313000.0 0.66 977712.0 284000.0 0.64 0.9251 0.9999 3025247 ChemDiv3_005053 Clc1ccccc1NC(=O)c2cc(nc3ccccc23)c4cccs4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F16 compound treatment 858952.0 179000.0 0.38 839162.0 145000.0 0.33 0.5018 0.9975 3119884 ChemDiv3_005054 COc1ccc(/C=C/2\Oc3cc(OC(=O)c4ccc(F)cc4)ccc3C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F17 compound treatment 862673.0 183000.0 0.39 816262.0 122000.0 0.28 0.4706 0.9866 1705934 ChemDiv3_005055 O=C(Nc1ccccc1)N2CCN3C(=O)c4ccccc4C23c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F18 compound treatment 198890.0 -481000.0 -1.02 199027.0 -495000.0 -1.13 -1.5168 -0.9988 3025248 ChemDiv3_005056 CCc1ccc(Oc2c(oc3c(CN(C)C)c(O)ccc3c2=O)C(F)(F)F)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F19 compound treatment 828279.0 148000.0 0.31 935154.0 241000.0 0.55 0.6101 0.9654 1681490 ChemDiv3_005057 CCOc1ccc2[nH]c(SCC(=O)Nc3ccccc3)nc2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F20 compound treatment 653852.0 -25900.0 -0.05 743143.0 49000.0 0.11 0.04 0.3216 3119885 ChemDiv3_005058 COc1ccc(cc1)c2c3C(=O)CC(C)(C)Cc3nc4sc(C(=O)N5CCCCCC5)c(N)c24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F21 compound treatment 811710.0 132000.0 0.28 943026.0 249000.0 0.57 0.598 0.9472 1693546 ChemDiv3_005059 Cc1cc(C)c(c(C)c1)S(=O)(=O)N2CCN(Cc3ccc4OCOc4c3)CC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F22 compound treatment 843671.0 164000.0 0.35 916638.0 223000.0 0.51 0.6034 0.9832 3025249 ChemDiv3_005060 Cc1ccc(NC(=O)CSc2nnc3ccccn23)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F23 mock treatment 782351.0 103000.0 0.22 1006424.0 312000.0 0.71 0.6559 0.8832 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 F24 mock treatment 521183.0 -159000.0 -0.34 686016.0 -8080.0 -0.02 -0.2507 -0.7446 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G01 compound treatment 518811.0 -161000.0 -0.34 539811.0 -154000.0 -0.35 -0.4893 -0.9999 3119886 ChemDiv3_005061 O/C(=C\1/CCC/C(=C\c2ccccc2)/C1=O)/C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G02 compound treatment 560372.0 -119000.0 -0.25 505150.0 -189000.0 -0.43 -0.4828 -0.9682 1563591 ChemDiv3_005062 S=C1NC2(CCS1)Oc3ccccc3C4CC(=NN42)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G03 compound treatment 1005439.0 326000.0 0.69 958472.0 264000.0 0.6 0.9132 0.9976 3025250 ChemDiv3_005063 CCOC(=O)c1cnc2c(C#N)c(C)nn2c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G04 compound treatment 931341.0 252000.0 0.53 861742.0 168000.0 0.38 0.6466 0.9864 3119887 ChemDiv3_005064 CC(=C)CC(Nc1ccccc1F)c2ccco2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G05 compound treatment 981795.0 302000.0 0.64 827405.0 133000.0 0.3 0.667 0.9417 3025251 ChemDiv3_005065 CCOc1ccc(NC(=O)C2CCN(CC2)C(=O)c3ccccc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G06 compound treatment 1079985.0 400000.0 0.85 931113.0 237000.0 0.54 0.981 0.976 3119888 ChemDiv3_005066 FC(F)(F)c1cccc(CN2c3cccc4cccc(c34)S2(=O)=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G07 compound treatment 1151136.0 471000.0 1.0 892352.0 198000.0 0.45 1.0253 0.9353 3025252 ChemDiv3_005067 Cc1ccc(cc1)c2csc(n2)N3C(=O)CN=C3SCc4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G08 compound treatment 258890.0 -421000.0 -0.89 245933.0 -448000.0 -1.02 -1.3514 -0.9978 3119889 ChemDiv3_005068 COc1ccc(/N=c/2\cc(oc3ccc(O)cc23)c4ccc(OC)cc4)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G09 compound treatment 1199499.0 520000.0 1.1 881594.0 187000.0 0.43 1.0805 0.9146 3119890 ChemDiv3_005069 CN/1C(=O)/C(=C/c2cccs2)/S\C1=N\c3ccc(cc3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G10 compound treatment 95489.0 -584000.0 -1.24 119991.0 -574000.0 -1.31 -1.7988 -0.9997 1551423 ChemDiv3_005070 CCN(CC)CC(O)COc1ccc(cc1C(C)(C)CC)C(C)(C)CC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G11 compound treatment 1126571.0 447000.0 0.95 1000636.0 307000.0 0.7 1.1626 0.9886 3119891 ChemDiv3_005071 CCN1C(=O)/C(=C/c2ccco2)/NC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G12 compound treatment 1275587.0 596000.0 1.26 949971.0 256000.0 0.58 1.3045 0.9381 1281346 ChemDiv3_005072 COc1ccc(NC(=O)c2cc[nH]n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G13 compound treatment 1236486.0 557000.0 1.18 946100.0 252000.0 0.57 1.2397 0.9449 3119892 ChemDiv3_005073 CC(=O)N1N=C(OC1c2cccnc2)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G14 compound treatment 1045911.0 366000.0 0.78 989454.0 295000.0 0.67 1.0237 0.9974 3025253 ChemDiv3_005074 COC(=O)C1Cc2c([nH]c3ccccc23)C(C)N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G15 compound treatment 1176034.0 496000.0 1.05 837442.0 143000.0 0.33 0.9744 0.8847 1321601 ChemDiv3_005075 CC(C)Nc1nc(NC(C)C)nc(n1)N(n2cnnc2)S(=O)(=O)c3ccc(C)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G16 compound treatment 1191588.0 512000.0 1.09 997063.0 303000.0 0.69 1.2543 0.976 3025254 ChemDiv3_005076 CC(C)CN1CN(Cc2ccco2)CNC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G17 compound treatment 1115865.0 436000.0 0.92 984253.0 290000.0 0.66 1.1202 0.9863 3119893 ChemDiv3_005077 CC1(C)CC(CCC(=O)NC(=S)Nc2ccccc2Cl)C(=O)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G18 compound treatment 1259475.0 580000.0 1.23 971999.0 278000.0 0.63 1.3158 0.9522 3119894 ChemDiv3_005078 COC(=O)c1ccc(Oc2nc(Nc3ccccc3F)nc(n2)N4CCCCC4C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G19 compound treatment 963002.0 283000.0 0.6 914683.0 221000.0 0.5 0.7792 0.996 3025255 ChemDiv3_005079 Clc1c2C(=O)/C(=C/NCc3ccccc3)/Nc2ccc1Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G20 compound treatment 936597.0 257000.0 0.54 884552.0 190000.0 0.43 0.6912 0.9936 3119895 ChemDiv3_005080 CN1CCc2c(C1=O)n(CC(O)Cn3nc(C)c(Br)c3C)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G21 compound treatment 1009907.0 330000.0 0.7 827376.0 133000.0 0.3 0.7091 0.9298 3025256 ChemDiv3_005081 COc1ccc(/C=C/C(=O)CC(=O)c2ccccc2O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G22 compound treatment 953434.0 274000.0 0.58 955467.0 261000.0 0.59 0.8304 0.9999 3119896 ChemDiv3_005082 O=C1OC(N2CCN(CCNC=C3C(=O)CC(CC3=O)c4ccccc4)CC2)c5ccccc15 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G23 mock treatment 860697.0 181000.0 0.38 855009.0 161000.0 0.37 0.5299 0.9997 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 G24 mock treatment 790566.0 111000.0 0.23 743891.0 49800.0 0.11 0.2461 0.944 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H01 compound treatment 516383.0 -163000.0 -0.35 512731.0 -181000.0 -0.41 -0.5365 -0.9962 3025257 ChemDiv3_005083 CC1(C)CC(CC(C)(C)N1)NC(=S)Nc2ccc(cc2)S(=O)(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H02 compound treatment 766537.0 86800.0 0.18 643240.0 -50900.0 -0.12 0.0483 0.2223 3119897 ChemDiv3_005084 CCC1=[N+]([O-])C(C)(N(O)C1(C)C)/C(=N\O)/C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H03 compound treatment 740243.0 60500.0 0.13 662718.0 -31400.0 -0.07 0.0402 0.274 1599271 ChemDiv3_005085 Cc1ccc(SCC(=O)n2c3ccccc3c4ccccc24)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H04 compound treatment 779413.0 99600.0 0.21 779361.0 85300.0 0.19 0.2864 0.9991 3119898 ChemDiv3_005086 CCN1C(=O)/C(=C\c2cccc3C(=O)c4ccccc4-c32)/OC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H05 compound treatment 778347.0 98600.0 0.21 699361.0 5270.0 0.01 0.1562 0.7464 3119899 ChemDiv3_005087 Cc1ccc(Nc2nc(N)nc(CC(=O)CSc3nc4ccccc4s3)n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H06 compound treatment 887823.0 208000.0 0.44 837173.0 143000.0 0.33 0.5419 0.9888 3025258 ChemDiv3_005088 CCOC(=O)c1nc(N)c(=O)n(n1)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H07 compound treatment 720905.0 41100.0 0.09 676189.0 -17900.0 -0.04 0.0329 0.3415 1535790 ChemDiv3_005089 Cc1ccc(cc1)C(=O)OC2=C(C(=O)c3ccccc3C2=O)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H08 compound treatment 267819.0 -412000.0 -0.87 210380.0 -484000.0 -1.1 -1.3952 -0.9935 3025259 ChemDiv3_005090 O=C1c2ncn(c2C(=O)c3ccccc13)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H09 compound treatment 585205.0 -94600.0 -0.2 579761.0 -114000.0 -0.26 -0.3256 -0.9918 3119900 ChemDiv3_005091 CS(=O)(=O)Nc1cc(ccc1N2CCOCC2)c3nnc(Nc4ccccc4)c5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H10 compound treatment 949151.0 269000.0 0.57 890976.0 197000.0 0.45 0.7203 0.9927 3025260 ChemDiv3_005092 CCOC(=O)C1C(c2cc(Br)ccc2OC1=O)C3(CCCCC3)C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H11 compound treatment 1106184.0 426000.0 0.9 950938.0 257000.0 0.58 1.0521 0.9776 3119901 ChemDiv3_005093 CCN(CC)c1ccc(cc1)n2c(C)cc(/C=C\3/NC(=O)N(Cc4ccccc4F)C3=O)c2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H12 compound treatment 1093358.0 414000.0 0.88 987449.0 293000.0 0.67 1.0916 0.9909 1277443 ChemDiv3_005094 COc1ccc(cc1)n2c(N)c(c3nc4ccccc4s3)c5nc(C#N)c(C#N)nc25 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H13 compound treatment 1137563.0 458000.0 0.97 903258.0 209000.0 0.48 1.0225 0.9461 3119902 ChemDiv3_005095 CCN1C(=O)/C(=C/c2ccc(Cl)cc2)/NC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H14 compound treatment 1366250.0 686000.0 1.46 1047045.0 353000.0 0.8 1.5965 0.9606 1602494 ChemDiv3_005096 O=C(CSc1nc2CCCCc2cc1C#N)N3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H15 compound treatment 552434.0 -127000.0 -0.27 496118.0 -198000.0 -0.45 -0.5092 -0.9701 3025261 ChemDiv3_005097 Cc1ccc(C)c(NC(CC(=O)c2ccccc2)C(=O)O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H16 compound treatment 1247496.0 568000.0 1.2 1130737.0 437000.0 0.99 1.553 0.9954 3119903 ChemDiv3_005098 COc1ccc(/C=C/2\Oc3cc(OCc4cccc(C)c4)ccc3C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H17 compound treatment 292275.0 -388000.0 -0.82 230319.0 -464000.0 -1.05 -1.3265 -0.9924 1119051 ChemDiv3_005099 CC1(C)NC(=O)N(CC(O)Cn2c3ccccc3c4ccccc24)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H18 compound treatment 797411.0 118000.0 0.25 697876.0 3780.0 0.01 0.1824 0.731 3025262 ChemDiv3_005100 COc1ccc(CCNC(=O)COc2ccc3c(=O)c(coc3c2)c4ccccc4)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H19 compound treatment 1016284.0 337000.0 0.71 950308.0 256000.0 0.58 0.9163 0.9949 3120046 ChemDiv3_005101 Clc1ccc(CSc2nc3ccccc3s2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H20 compound treatment 950799.0 271000.0 0.57 890374.0 196000.0 0.45 0.7218 0.9922 3025263 ChemDiv3_005102 Cc1nc2cc(NS(=O)(=O)c3ccc(Oc4ccccc4)cc3)ccc2s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H21 compound treatment 1037356.0 358000.0 0.76 883413.0 189000.0 0.43 0.8404 0.964 3120047 ChemDiv3_005103 CS(=O)(=O)N1CCC(CC1)C(=O)NCCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H22 compound treatment 960568.0 281000.0 0.6 930527.0 236000.0 0.54 0.801 0.9987 3120048 ChemDiv3_005104 O=C(CSc1nnc2ccccn12)N3CCOCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H23 mock treatment 869840.0 190000.0 0.4 844325.0 150000.0 0.34 0.5264 0.9966 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 H24 mock treatment 455553.0 -224000.0 -0.48 592655.0 -101000.0 -0.23 -0.4992 -0.9448 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I01 compound treatment 616833.0 -62900.0 -0.13 573960.0 -120000.0 -0.27 -0.2875 -0.9457 1405649 ChemDiv3_005105 COc1cccc(NC(=O)COc2ccc(cc2)N3CC(CC3=O)C(=O)NCC(C)C)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I02 compound treatment 976800.0 297000.0 0.63 945454.0 251000.0 0.57 0.8493 0.9988 1546533 ChemDiv3_005106 Cc1ccc(cc1)N2C(=O)C3Sc4[nH]c(=O)sc4C(C3C2=O)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I03 compound treatment 783160.0 103000.0 0.22 815830.0 122000.0 0.28 0.3507 0.9933 1209298 ChemDiv3_005107 CCOC(=O)c1cnc2c(cnn2c1C)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I04 compound treatment 970099.0 290000.0 0.62 980752.0 287000.0 0.65 0.896 0.9996 1582005 ChemDiv3_005108 Cc1ccc(cc1)N2CC3(OC4C=C3)C(C4C(=O)O)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I05 compound treatment 882892.0 203000.0 0.43 907247.0 213000.0 0.48 0.6471 0.9983 3120049 ChemDiv3_005109 CCc1ccc(NC(=O)C2CCN(CC2)C(=O)c3ccccc3C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I06 compound treatment 1113678.0 434000.0 0.92 1096256.0 402000.0 0.91 1.297 1.0 3025264 ChemDiv3_005110 Brc1cccc(CN2c3cccc4cccc(c34)S2(=O)=O)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I07 compound treatment 993279.0 313000.0 0.66 938388.0 244000.0 0.56 0.8627 0.996 3120050 ChemDiv3_005111 N/C(=N\c1nc(=O)c2CCCCc2[nH]1)/Nc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I08 compound treatment 286788.0 -393000.0 -0.83 282793.0 -411000.0 -0.94 -1.2503 -0.9983 3120051 ChemDiv3_005112 COc1ccc(cc1)c2c/c(=N\c3ccc(C)cc3C)/c4cc(O)ccc4o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I09 compound treatment 1191070.0 511000.0 1.08 1068254.0 374000.0 0.85 1.368 0.9928 3025265 ChemDiv3_005113 CCN/1C(=O)CS\C1=N\c2cccc(c2)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I10 compound treatment 1156118.0 476000.0 1.01 1054226.0 360000.0 0.82 1.293 0.9946 1298232 ChemDiv3_005114 O=C(Oc1cccc2cccnc12)N3CCCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I11 compound treatment 1252251.0 572000.0 1.21 1151943.0 458000.0 1.04 1.5942 0.9971 3120052 ChemDiv3_005115 CCCCN1C(=O)S/C(=C\c2cc(C)n(C)c2C)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I12 compound treatment 1025855.0 346000.0 0.73 1120749.0 427000.0 0.97 1.2047 0.9905 1336653 ChemDiv3_005116 CCC(=O)n1ccc(n1)C(=O)N2CCOCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I13 compound treatment 1146272.0 466000.0 0.99 1296133.0 602000.0 1.37 1.6671 0.9873 3025316 ChemDiv3_005117 CC(=O)N1N=C(OC21CCCC2)c3ccc4ccccc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I14 compound treatment 627771.0 -52000.0 -0.11 555808.0 -138000.0 -0.31 -0.3003 -0.9013 3025317 ChemDiv3_005118 Cc1ccc(cc1)C2NC(=S)NC(=C2)C3(CC4CC5CC(C4)C3)C5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I15 compound treatment 1271843.0 592000.0 1.26 1100950.0 407000.0 0.93 1.5416 0.9887 3025318 ChemDiv3_005119 COC(=O)NCCOc1nc(nc(n1)N(C)C)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I16 compound treatment 1157229.0 477000.0 1.01 839356.0 145000.0 0.33 0.9492 0.8916 3025319 ChemDiv3_005120 CCN1CNC(=S)N(C1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I17 compound treatment 1189008.0 509000.0 1.08 943792.0 250000.0 0.57 1.1648 0.955 3025320 ChemDiv3_005121 CC(C)c1ccc(C)cc1OCC(=O)Nn2c(=O)[nH]c3ccccc3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I18 compound treatment 1174666.0 495000.0 1.05 1054467.0 360000.0 0.82 1.3212 0.9925 3025321 ChemDiv3_005122 CCN(CC)c1ccc(cc1)c2cc(C(=O)O)c3c(ccc4ccccc43)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I19 compound treatment 1122645.0 443000.0 0.94 996063.0 302000.0 0.69 1.1493 0.9882 3025322 ChemDiv3_005123 O=C/1Nc2ccccc2\C1=C\NCCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I20 compound treatment 655972.0 -23800.0 -0.05 547068.0 -147000.0 -0.33 -0.2721 -0.8047 3120053 ChemDiv3_005124 CN1CCc2c(C1=O)n(CC(O)CNCc3ccccc3)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I21 compound treatment 921673.0 242000.0 0.51 851567.0 157000.0 0.36 0.6158 0.9846 3025323 ChemDiv3_005125 O=c1cc(/C=C/c2ccccc2)oc3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I22 compound treatment 876564.0 197000.0 0.42 832054.0 138000.0 0.31 0.5168 0.9901 3120054 ChemDiv3_005126 CCCNC(=O)CSc1c(c2ccccc2)c3cc(Cl)ccc3[nH]c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I23 mock treatment 1027565.0 348000.0 0.74 933053.0 239000.0 0.54 0.9055 0.9887 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 I24 mock treatment 497878.0 -182000.0 -0.39 676240.0 -17900.0 -0.04 -0.3014 -0.7773 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J01 compound treatment 517054.0 -163000.0 -0.34 482977.0 -211000.0 -0.48 -0.5833 -0.9869 3025324 ChemDiv3_005127 CCCCc1ccc(NC(=S)NCCCN2CCOCC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J02 compound treatment 799397.0 120000.0 0.25 740451.0 46400.0 0.11 0.2538 0.9243 3120055 ChemDiv3_005128 CC1=[N+]([O-])C2(CCCC2)[N+](=C1c3ccccc3)[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J03 compound treatment 778029.0 98200.0 0.21 735746.0 41700.0 0.09 0.2142 0.9364 3120056 ChemDiv3_005129 O=C(Nc1ccccc1)C2CC(=O)NC(=N2)Nc3nc4ccccc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J04 compound treatment 836749.0 157000.0 0.33 735647.0 41600.0 0.09 0.3021 0.8733 3025325 ChemDiv3_005130 Cc1ccc(NS(=O)(=O)c2ccc3n(C(=O)Oc4ccccc4)c(=O)oc3c2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J05 compound treatment 585642.0 -94100.0 -0.2 693055.0 -1040.0 0.0 -0.1428 -0.7154 3120057 ChemDiv3_005131 COc1ccc(Cl)cc1Nc2nc(N)nc(CC(=O)CSc3nc4ccccc4s3)n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J06 compound treatment 1121540.0 442000.0 0.94 957097.0 263000.0 0.6 1.085 0.9765 1919405 ChemDiv3_005132 CCn1c2ccccc2c3nnc(S)nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J07 compound treatment 109949.0 -570000.0 -1.21 164344.0 -530000.0 -1.2 -1.7058 -1.0 3025326 ChemDiv3_005133 Fc1ccc(cc1)C2Sc3ccccc3N=C4C2C(=O)c5ccccc45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J08 compound treatment 1104143.0 424000.0 0.9 990762.0 297000.0 0.67 1.1131 0.9899 3120058 ChemDiv3_005134 Cc1cccc(c1)C(=O)NCCCn2ccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J09 compound treatment 265279.0 -415000.0 -0.88 205849.0 -488000.0 -1.11 -1.4063 -0.9933 3120059 ChemDiv3_005135 CCN(CC)C(=O)COc1ccc(cc1)c2nnc(Nc3ccc(OC)c(c3)C(=O)N)c4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J10 compound treatment 1465000.0 785000.0 1.66 1070713.0 377000.0 0.86 1.7825 0.9522 3025327 ChemDiv3_005136 CCCC(CCC)C(=O)Nc1cc(cc(c1)C(=O)O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J11 compound treatment 1022418.0 343000.0 0.73 892462.0 198000.0 0.45 0.8325 0.9737 1472732 ChemDiv3_005137 Cc1ccc(NC2CS(=O)(=O)C=C2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J12 compound treatment 1584095.0 904000.0 1.92 1106257.0 412000.0 0.94 2.0182 0.9458 1452920 ChemDiv3_005138 OC(=O)CCC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J13 compound treatment 1212141.0 532000.0 1.13 882063.0 188000.0 0.43 1.1002 0.9117 3120060 ChemDiv3_005139 CCOc1ccc(cc1)N2C(=O)/C(=C/c3ccccc3)/N(C)C2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J14 compound treatment 1091964.0 412000.0 0.87 994851.0 301000.0 0.68 1.1014 0.9926 3025328 ChemDiv3_005140 CC(C)c1ccccc1Oc2coc3cc(OCC(=O)NC4CCCCC4)ccc3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J15 compound treatment 1462133.0 782000.0 1.66 1087855.0 394000.0 0.9 1.8058 0.9581 1599429 ChemDiv3_005141 COc1ccc(cc1)c2cc(C(=O)OCC(=O)c3ccccc3)c4cccc(Cl)c4n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J16 compound treatment 1157832.0 478000.0 1.01 882699.0 189000.0 0.43 1.0198 0.9267 3025329 ChemDiv3_005142 COc1cc(cc(OC)c1OC)C(=O)Oc2ccc3C(=O)COc3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J17 compound treatment 1152322.0 473000.0 1.0 911794.0 218000.0 0.49 1.0583 0.9472 3120061 ChemDiv3_005143 COCn1c(nc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J18 compound treatment 1107928.0 428000.0 0.91 774926.0 80800.0 0.18 0.7718 0.8334 1585270 ChemDiv3_005144 CCCc1cc(ccn1)c2nc(cs2)c3ccc(Br)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J19 compound treatment 1067917.0 388000.0 0.82 909201.0 215000.0 0.49 0.9276 0.9691 3025330 ChemDiv3_005145 COc1ccc(CSc2nc3ccccc3s2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J20 compound treatment 1094122.0 414000.0 0.88 875860.0 182000.0 0.41 0.9133 0.9409 3120062 ChemDiv3_005146 Cc1nnc(SCCC(=O)Nc2cccc(c2)c3nc4ccccc4s3)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J21 compound treatment 159195.0 -521000.0 -1.1 188684.0 -505000.0 -1.15 -1.5929 -0.9998 3025331 ChemDiv3_005147 CN/1C(=S)N(C2CCCCC2)C(=O)\C1=C\c3ccccc3O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J22 compound treatment 1004340.0 325000.0 0.69 994970.0 301000.0 0.68 0.9702 1.0 3120063 ChemDiv3_005148 O=C(CCSc1nnc2ccccn12)Nc3cccc(c3)c4nc5ccccc5s4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J23 mock treatment 1079150.0 399000.0 0.85 922292.0 228000.0 0.52 0.9655 0.9724 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 J24 mock treatment 817459.0 138000.0 0.29 707147.0 13100.0 0.03 0.2274 0.775 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K01 compound treatment 552395.0 -127000.0 -0.27 603966.0 -90100.0 -0.2 -0.3358 -0.9907 3120064 ChemDiv3_005149 COc1ccc(cc1)N2CC(CC2=O)C(=O)OCC(=O)Nc3ccccc3C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K02 compound treatment 727423.0 47600.0 0.1 677690.0 -16400.0 -0.04 0.045 0.4184 3025332 ChemDiv3_005150 Cc1ccccc1NC(CC=C)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K03 compound treatment 607156.0 -72600.0 -0.15 576171.0 -118000.0 -0.27 -0.2984 -0.9653 3025333 ChemDiv3_005151 CC(C)(C)c1ccc(cc1)c2cc3ncc(c(N)n3n2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K04 compound treatment 823757.0 144000.0 0.31 840576.0 146000.0 0.33 0.4513 0.9991 1246311 ChemDiv3_005152 OC(=O)C1C2OC3(CN(CCc4ccccc4)C(=O)C13)C=C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K05 compound treatment 804876.0 125000.0 0.27 874424.0 180000.0 0.41 0.4774 0.9778 3120065 ChemDiv3_005153 CC(C)CNC(=O)C1CCN(CC1)C(=O)c2ccc(F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K06 compound treatment 943319.0 264000.0 0.56 959619.0 266000.0 0.6 0.8219 0.9993 1524928 ChemDiv3_005154 Cc1ccc(cc1)c2csc3ncnc(NCCC(=O)O)c23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K07 compound treatment 946464.0 267000.0 0.57 916659.0 223000.0 0.51 0.7576 0.9985 3120066 ChemDiv3_005155 COc1cc(OC)cc(c1)C2=NC(C)(C)CO2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K08 compound treatment 895243.0 215000.0 0.46 892864.0 199000.0 0.45 0.6425 1.0 1424113 ChemDiv3_005156 CC(C)Oc1ccccc1Nc2ncnc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K09 compound treatment 970349.0 291000.0 0.62 922138.0 228000.0 0.52 0.8022 0.9963 3120067 ChemDiv3_005157 Oc1ccc(/C=C/2\SC(=O)N(CC(=O)N3CCOCC3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K10 compound treatment 895828.0 216000.0 0.46 983635.0 290000.0 0.66 0.7893 0.9843 3120068 ChemDiv3_005158 COc1ccc(CCN2C(=O)CC(Sc3ccccc3C(=O)O)C2=O)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K11 compound treatment 1029681.0 350000.0 0.74 1024391.0 330000.0 0.75 1.0555 1.0 3025334 ChemDiv3_005159 C=CCn1cc(C=C2C(=O)OC(OC2=O)c3ccccc3)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K12 compound treatment 1245266.0 565000.0 1.2 1095262.0 401000.0 0.91 1.4926 0.9909 1125429 ChemDiv3_005160 Clc1ccc(C(=O)n2ccc(n2)C(=O)N3CCCCC3)c(Cl)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K13 compound treatment 1074718.0 395000.0 0.84 1099803.0 406000.0 0.92 1.2443 0.9988 3025335 ChemDiv3_005161 O=C(Nc1cccc2cccnc12)/C=C/c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K14 compound treatment 865630.0 186000.0 0.39 986123.0 292000.0 0.66 0.7481 0.969 3117769 ChemDiv3_005162 CC1C/C(=C\c2ccc(Cl)cc2)/C3=C(C1)C(NC(=S)N3)c4ccc(Cl)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K15 compound treatment 752230.0 72500.0 0.15 722067.0 28000.0 0.06 0.1536 0.9238 1289908 ChemDiv3_005163 CCNc1nc(Oc2ccc(cc2)C(=O)OC)nc(SC)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K16 compound treatment 990146.0 310000.0 0.66 872608.0 179000.0 0.41 0.7522 0.973 3117770 ChemDiv3_005164 CCN1CNC(=S)N(C1)C2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K17 compound treatment 1131459.0 452000.0 0.96 1017731.0 324000.0 0.74 1.1974 0.9915 1050895 ChemDiv3_005165 Cc1ccc(cc1)S(=O)(=O)N2Cc3ccccc3C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K18 compound treatment 1064617.0 385000.0 0.82 976285.0 282000.0 0.64 1.0305 0.9929 3117771 ChemDiv3_005166 Cc1ccc(NC(=O)CCn2nnc(n2)c3ccc(OCc4ccccc4F)cc3)cc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K19 compound treatment 988784.0 309000.0 0.66 996861.0 303000.0 0.69 0.9499 0.9997 3025336 ChemDiv3_005167 Cc1ccccc1N/C=C/2\C(=O)Nc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K20 compound treatment 1049936.0 370000.0 0.78 996003.0 302000.0 0.69 1.0402 0.9978 3117772 ChemDiv3_005168 O=C1OC(N2CCc3ccccc3C2)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K21 compound treatment 1083554.0 404000.0 0.86 916656.0 223000.0 0.51 0.9631 0.9685 3117773 ChemDiv3_005169 Cc1ccc(cc1)c2cc(=O)c3ccc4ccccc4c3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K22 compound treatment 912806.0 233000.0 0.49 951559.0 257000.0 0.59 0.7632 0.9964 3025337 ChemDiv3_005170 Cc1ccc(cc1)S(=O)(=O)CC(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K23 mock treatment 817152.0 137000.0 0.29 808142.0 114000.0 0.26 0.3893 0.9983 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 K24 mock treatment 469650.0 -210000.0 -0.45 565023.0 -129000.0 -0.29 -0.5225 -0.9795 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L01 compound treatment 501360.0 -178000.0 -0.38 494117.0 -200000.0 -0.45 -0.589 -0.9958 3117774 ChemDiv3_005171 NS(=O)(=O)c1ccc(NC(=S)N2CCc3ccccc3C2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L02 compound treatment 886874.0 207000.0 0.44 666230.0 -27900.0 -0.06 0.2656 0.5989 3025338 ChemDiv3_005172 CCC1(C)[N+](=C(C)C(=[N+]1[O-])c2ccccc2)[O-] 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L03 compound treatment 211508.0 -468000.0 -0.99 252820.0 -441000.0 -1.0 -1.4114 -1.0 3117775 ChemDiv3_005173 CCOc1ccc2NC(C)(C)c3ss/c(=N\c4ccc(NC(=O)C)cc4)/c3-c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L04 compound treatment 884590.0 205000.0 0.43 892395.0 198000.0 0.45 0.6258 0.9998 3117776 ChemDiv3_005174 CC(C)Cn1c2ccc(Br)cc2c3nc4ccccc4nc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L05 compound treatment 885116.0 205000.0 0.44 815460.0 121000.0 0.28 0.5029 0.9758 1871645 ChemDiv3_005175 COc1ccc(CC(=O)N(CC=C)c2nnc(s2)c3ccc(Cl)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L06 compound treatment 779127.0 99300.0 0.21 736868.0 42800.0 0.1 0.2177 0.9384 3117777 ChemDiv3_005176 CCc1ccc2[nH]c3nc(S)nnc3c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L07 compound treatment 1042311.0 363000.0 0.77 803770.0 110000.0 0.25 0.7198 0.8908 3117778 ChemDiv3_005177 CCc1ccc(cc1)N2NC(=O)/C(=C/c3ccc4n(C)c(=O)n(C)c4c3)/C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L08 compound treatment 920016.0 240000.0 0.51 806661.0 113000.0 0.26 0.5411 0.9493 3025339 ChemDiv3_005178 CC(CN1C(C)CCCC1C)OC(=O)c2ccc(C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L09 compound treatment 939701.0 260000.0 0.55 975424.0 281000.0 0.64 0.8419 0.9972 3117779 ChemDiv3_005179 O=C/1NC(=S)S\C1=C/c2c(NCc3ccco3)nc4ccccn4c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L10 compound treatment 1155933.0 476000.0 1.01 950581.0 256000.0 0.58 1.1261 0.966 3025340 ChemDiv3_005180 CCC(=O)Oc1ccc(cc1)C(=O)Nc2cc(cc(c2)C(=O)O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L11 compound treatment 1083569.0 404000.0 0.86 925829.0 232000.0 0.53 0.9778 0.9728 3117780 ChemDiv3_005181 COC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCc3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L12 compound treatment 1343294.0 664000.0 1.41 1082937.0 389000.0 0.88 1.6198 0.975 3025341 ChemDiv3_005182 OC(=O)c1cc(/N=C\c2ccc(N3CCCC3)c(F)c2)ccc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L13 compound treatment 297719.0 -382000.0 -0.81 279532.0 -415000.0 -0.94 -1.2392 -0.9972 3117781 ChemDiv3_005183 CN/1C(=S)N(C(=O)\C1=C\c2ccccc2O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L14 compound treatment 1185082.0 505000.0 1.07 844714.0 151000.0 0.34 0.9996 0.8888 3117782 ChemDiv3_005184 Cc1ccc(Oc2coc3cc(OCC(=O)N4CCCCC4)ccc3c2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L15 compound treatment 1364195.0 684000.0 1.45 853035.0 159000.0 0.36 1.2815 0.857 3025342 ChemDiv3_005185 CCCC/1=NN(C(=O)\C1=C\c2ccc3OCOc3c2)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L16 compound treatment 1313417.0 634000.0 1.34 902910.0 209000.0 0.47 1.2855 0.9023 1224155 ChemDiv3_005186 CC(Oc1ccc2c(=O)c(coc2c1)c3ccc(Cl)cc3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L17 compound treatment 1237526.0 558000.0 1.18 923207.0 229000.0 0.52 1.2044 0.9322 1151018 ChemDiv3_005187 CCCCn1c(nc2ccccc12)c3ccc(OC)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L18 compound treatment 1127901.0 448000.0 0.95 986727.0 293000.0 0.67 1.1422 0.9848 3117783 ChemDiv3_005188 Cc1ncc2COC(C)(C)OCc2c1OC(=O)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L19 compound treatment 1088223.0 408000.0 0.87 904094.0 210000.0 0.48 0.9499 0.9606 3025343 ChemDiv3_005189 NC(=O)/C(=C\1/Oc2c(S1)cc(O)cc2c3ccccc3)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L20 compound treatment 1331657.0 652000.0 1.38 1005742.0 312000.0 0.71 1.4782 0.9518 3117784 ChemDiv3_005190 COc1ccc(NC(=O)CCSc2ccc3ccccc3n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L21 compound treatment 1155004.0 475000.0 1.01 811953.0 118000.0 0.27 0.9019 0.8651 3117785 ChemDiv3_005191 CCCN1C(=O)/C(=C/c2ccc(CC)cc2)/NC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L22 compound treatment 1257965.0 578000.0 1.23 925454.0 231000.0 0.53 1.2387 0.9287 3025344 ChemDiv3_005192 O=C(CSc1nnc2ccc3ccccc3n12)NCC4CCCO4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L23 mock treatment 1165006.0 485000.0 1.03 983511.0 289000.0 0.66 1.1926 0.9767 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 L24 mock treatment 562320.0 -117000.0 -0.25 577725.0 -116000.0 -0.26 -0.3632 -0.9995 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M01 compound treatment 546113.0 -134000.0 -0.28 442221.0 -252000.0 -0.57 -0.6053 -0.9474 3117786 ChemDiv3_005193 OC(=O)CCc1ccc(c2ccccc2)n1NC(=O)c3ccccc3Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M02 compound treatment 591859.0 -87900.0 -0.19 463551.0 -231000.0 -0.52 -0.5024 -0.9031 3025345 ChemDiv3_005194 Cc1ccc(o1)c2cccc(c2)n3c(C)ccc3c4cccc(N)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M03 compound treatment 835060.0 155000.0 0.33 686333.0 -7760.0 -0.02 0.2203 0.6682 3117787 ChemDiv3_005195 COc1ccc(cc1)C2=C/C(=C/c3ccccc3)/C(=O)O2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M04 compound treatment 841934.0 162000.0 0.34 838256.0 144000.0 0.33 0.4748 0.9997 3025395 ChemDiv3_005196 CC1CC2N(C(=O)c3c2cccc3C(=O)O)c4ccc(F)cc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M05 compound treatment 970968.0 291000.0 0.62 829930.0 136000.0 0.31 0.6549 0.9488 3025396 ChemDiv3_005197 CCc1ccc(NC(=O)C2CCN(CC2)C(=O)c3ccc(F)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M06 compound treatment 923068.0 243000.0 0.52 749898.0 55800.0 0.13 0.4544 0.8555 1364255 ChemDiv3_005198 CCCC(=O)Oc1ccc2oc(cc(=O)c2c1)c3ccc(OC)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M07 compound treatment 1029072.0 349000.0 0.74 937245.0 243000.0 0.55 0.9145 0.9896 3025397 ChemDiv3_005199 CN1C(=O)/C(=C/c2cn(CC(=O)N3CCOCC3)c4ccccc24)/C(=O)NC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M08 compound treatment 966612.0 287000.0 0.61 999176.0 305000.0 0.69 0.9204 0.9978 3025398 ChemDiv3_005200 CCOC(=O)c1cnc2c(Cl)c(Cl)ccc2c1NCCOC(=O)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M09 compound treatment 820627.0 141000.0 0.3 840340.0 146000.0 0.33 0.4462 0.9986 3025399 ChemDiv3_005201 COc1ccccc1/C=C/2\SC(=O)N(CC(=O)N3CCOCC3)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M10 compound treatment 894938.0 215000.0 0.46 912845.0 219000.0 0.5 0.6742 0.9991 3025400 ChemDiv3_005202 OC(=O)CCNS(=O)(=O)c1ccccc1C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M11 compound treatment 1051333.0 372000.0 0.79 816642.0 123000.0 0.28 0.754 0.9024 3117788 ChemDiv3_005203 COc1ccc(C=C2C(=O)OC(OC2=O)c3ccccc3)c(OC)c1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M12 compound treatment 960011.0 280000.0 0.59 805725.0 112000.0 0.25 0.5995 0.928 3117789 ChemDiv3_005204 COc1ccc(/C=C/C(=O)C2CC2)cc1COc3cccc(C)c3C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M13 compound treatment 1144773.0 465000.0 0.99 972306.0 278000.0 0.63 1.1443 0.977 3025401 ChemDiv3_005205 Nc1oc2cc3c(C(=O)OCC=C)c(N)oc3c(c4ccccc4)c2c1C(=O)OCC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M14 compound treatment 821293.0 142000.0 0.3 817206.0 123000.0 0.28 0.4101 0.9994 3117790 ChemDiv3_005206 CC1C/C(=C\c2ccc(C)cc2)/C3=C(C1)C(NC(=S)N3)c4ccc(C)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M15 compound treatment 1049932.0 370000.0 0.78 801690.0 108000.0 0.24 0.7278 0.8855 3025402 ChemDiv3_005207 Cc1ccc(NC(=S)NC(=O)CC2CC(C)(C)OC2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M16 compound treatment 1051697.0 372000.0 0.79 842344.0 148000.0 0.34 0.7958 0.9281 1419022 ChemDiv3_005208 S=C1NCN(CCc2ccccc2)CN1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M17 compound treatment 1010760.0 331000.0 0.7 840315.0 146000.0 0.33 0.7312 0.9418 3117791 ChemDiv3_005209 N#Cc1nc(COc2ccccc2)oc1NCc3cccnc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M18 compound treatment 1106434.0 427000.0 0.9 954999.0 261000.0 0.59 1.059 0.9791 3025403 ChemDiv3_005210 Cn1nnc(n1)c2ccc(OCc3ccccc3F)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M19 compound treatment 1236332.0 557000.0 1.18 1030360.0 336000.0 0.76 1.3749 0.9779 3117792 ChemDiv3_005211 O=C/1Nc2ccccc2\C1=C\NCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M20 compound treatment 1141283.0 462000.0 0.98 1076964.0 383000.0 0.87 1.3073 0.9983 3117793 ChemDiv3_005212 Cc1noc(NS(=O)(=O)c2ccc(NC3OC(=O)c4ccccc34)cc2)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M21 compound treatment 1238353.0 559000.0 1.18 1056985.0 363000.0 0.83 1.4207 0.9844 3025404 ChemDiv3_005213 O=c1cc(oc2c1ccc3ccccc32)c4ccco4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M22 compound treatment 252530.0 -427000.0 -0.91 223976.0 -470000.0 -1.07 -1.3962 -0.9966 3025405 ChemDiv3_005214 CC(=C1C(=O)c2ccccc2C1=O)N3CCc4ccccc4C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M23 mock treatment 1048641.0 369000.0 0.78 868434.0 174000.0 0.4 0.8332 0.9504 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 M24 mock treatment 528194.0 -152000.0 -0.32 755487.0 61400.0 0.14 -0.1285 -0.3669 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N01 compound treatment 516128.0 -164000.0 -0.35 462800.0 -231000.0 -0.53 -0.6172 -0.9796 3117794 ChemDiv3_005215 NS(=O)(=O)c1ccc(NC(=S)N2CCC(Cc3ccccc3)CC2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N02 compound treatment 711315.0 31500.0 0.07 665374.0 -28700.0 -0.07 0.0011 0.0118 3025406 ChemDiv3_005216 C/C(=[N+](/[O-])\C\1CCC/C1=N\O)/C(=O)c2ccc(Cl)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N03 compound treatment 763038.0 83300.0 0.18 727779.0 33700.0 0.08 0.179 0.9301 3117795 ChemDiv3_005217 Sc1nnc(OCc2ccccc2)n1CC=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N04 compound treatment 592708.0 -87100.0 -0.18 636864.0 -57200.0 -0.13 -0.2225 -0.9854 3117796 ChemDiv3_005218 CC(C)c1ccc2[nH]c3/C(=N/O)/CCCc3c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N05 compound treatment 692123.0 12300.0 0.03 807522.0 113000.0 0.26 0.2009 0.7749 1457228 ChemDiv3_005219 Cn1c2N=C3C(C(c4cccc(Cl)c4)c2c(=O)n(C)c1=O)C(=O)c5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N06 compound treatment 858216.0 178000.0 0.38 806663.0 113000.0 0.26 0.4485 0.9819 3117929 ChemDiv3_005220 CCc1ccc2n(C)c3nc(S)nnc3c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N07 compound treatment 612260.0 -67500.0 -0.14 644107.0 -50000.0 -0.11 -0.1816 -0.9935 3117930 ChemDiv3_005221 COC(=O)C/1=C(C)NC(=O)\C1=C/c2cc(C)n(c2C)c3ccc(OC)c(Cl)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N08 compound treatment 653766.0 -26000.0 -0.06 698491.0 4400.0 0.01 -0.0319 -0.5697 3025407 ChemDiv3_005222 CC(C)(C)c1cc(cc(c1)C(C)(C)C)C(=O)NCCCn2ccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N09 compound treatment 641286.0 -38500.0 -0.08 682876.0 -11200.0 -0.03 -0.0757 -0.8859 3117931 ChemDiv3_005223 CC1=C(C(/C=C/c2ccccc2)N3C(=O)CCSC3=N1)C(=O)OCc4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N10 compound treatment 759191.0 79400.0 0.17 828965.0 135000.0 0.31 0.3359 0.9601 1320385 ChemDiv3_005224 OC(=O)c1ccc(cc1)C(=O)c2ccc3C(=O)N(CC4CCCO4)C(=O)c3c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N11 compound treatment 780363.0 101000.0 0.21 772119.0 78000.0 0.18 0.2762 0.9958 3025408 ChemDiv3_005225 CCCN(CCC)C(=O)c1cc2C(=O)CC(C)(C)Cc2n(c3ccc(Cl)c(Cl)c3)c1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N12 compound treatment 230886.0 -449000.0 -0.95 251990.0 -442000.0 -1.01 -1.3837 -0.9996 3117932 ChemDiv3_005226 CC1(C)Cc2ccccc2C(=N1)c3cc4ccccc4oc3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N13 compound treatment 670969.0 -8810.0 -0.02 767582.0 73500.0 0.17 0.1049 0.6242 3025409 ChemDiv3_005227 CCc1ccc(/C=C/2\N(C)C(=S)N(C2=O)c3ccc(C)c(C)c3)s1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N14 compound treatment 650545.0 -29200.0 -0.06 531151.0 -163000.0 -0.37 -0.3058 -0.8141 3117933 ChemDiv3_005228 CCCN(CCC)Cc1c(O)ccc2c(=O)c(coc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N15 compound treatment 774249.0 94500.0 0.2 831756.0 138000.0 0.31 0.3629 0.9767 3025410 ChemDiv3_005229 Oc1ccc(Br)cc1/C=N/c2sc3N4CCC(CC4)c3c2C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N16 compound treatment 183696.0 -496000.0 -1.05 162560.0 -532000.0 -1.21 -1.5982 -0.9976 3117934 ChemDiv3_005230 FC(F)(F)c1nnc2Sc3nc4ccccc4nc3Nn12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N17 compound treatment 803245.0 123000.0 0.26 762973.0 68900.0 0.16 0.2958 0.9698 1245770 ChemDiv3_005231 CCc1cccc(CC)c1N(COC)C(=O)Cn2c(Cc3ccccc3)nc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N18 compound treatment 932268.0 252000.0 0.54 871507.0 177000.0 0.4 0.6637 0.9903 3025411 ChemDiv3_005232 CC(=O)Oc1c(C)[n+](C)cc2COC(C)(C)OCc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N19 compound treatment 969701.0 290000.0 0.61 917100.0 223000.0 0.51 0.7931 0.9954 3117935 ChemDiv3_005233 CCCOc1ccc(/C=C\2/SC(=O)N(CN3CCCCC3)C2=O)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N20 compound treatment 919477.0 240000.0 0.51 952994.0 259000.0 0.59 0.7755 0.9973 3025412 ChemDiv3_005234 CC(C)(C)c1ccc(NC(=O)CCSc2ccc3ccccc3n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N21 compound treatment 871463.0 192000.0 0.41 832797.0 139000.0 0.32 0.5103 0.9921 1452765 ChemDiv3_005235 O=c1nc(CC#N)sc2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N22 compound treatment 796912.0 117000.0 0.25 754091.0 60000.0 0.14 0.272 0.9602 3117936 ChemDiv3_005236 COc1cccc(NC(=O)CCSc2nnc3ccc4ccccc4n23)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N23 mock treatment 849936.0 170000.0 0.36 788659.0 94600.0 0.21 0.4071 0.9694 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 N24 mock treatment 480906.0 -199000.0 -0.42 523524.0 -171000.0 -0.39 -0.5723 -0.9991 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O01 compound treatment 503113.0 -177000.0 -0.37 441236.0 -253000.0 -0.57 -0.6713 -0.9784 1414377 ChemDiv3_005237 Cc1ccc(cc1)c2ccc(CCC(=O)O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O02 compound treatment 752505.0 72700.0 0.15 703901.0 9810.0 0.02 0.1248 0.801 3025413 ChemDiv3_005238 CC(NC1(CC(=C)C)CCCCC1)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O03 compound treatment 901432.0 222000.0 0.47 907920.0 214000.0 0.49 0.676 0.9999 3117937 ChemDiv3_005239 COc1ccc(Br)c2Cc3sc(/N=C/c4ccc(C)cc4)nc3-c21 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O04 compound treatment 870141.0 190000.0 0.4 970278.0 276000.0 0.63 0.7294 0.9772 3117938 ChemDiv3_005240 OC(=O)c1cccc2C(CC=C)N(C(=O)c21)c3ccc(F)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O05 compound treatment 807935.0 128000.0 0.27 946364.0 252000.0 0.57 0.5977 0.9417 3025414 ChemDiv3_005241 CCC1CCC(CC1)c2nnc(o2)c3ccc(Br)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O06 compound treatment 903938.0 224000.0 0.48 1013436.0 319000.0 0.73 0.8494 0.9789 1327740 ChemDiv3_005242 COc1ccc(cc1)c2cc(=O)c3cc(OC(=O)Cc4ccccc4)ccc3o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O07 compound treatment 931137.0 251000.0 0.53 1096768.0 403000.0 0.92 1.0241 0.9668 3025415 ChemDiv3_005243 CN1C(=O)/C(=C/c2cc(C)n(c2C)c3ccc(cc3)C(=O)O)/C(=O)NC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O08 compound treatment 829115.0 149000.0 0.32 1061841.0 368000.0 0.84 0.8151 0.9117 3117939 ChemDiv3_005244 CCC(=O)OCCNc1nc(nc2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O09 compound treatment 914659.0 235000.0 0.5 907639.0 214000.0 0.49 0.6954 0.9999 3025416 ChemDiv3_005245 CCOC(=O)C1=C(NC(=O)c2ccc(C)cc2)S/C(=C\c3cccs3)/C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O10 compound treatment 837393.0 158000.0 0.33 942362.0 248000.0 0.56 0.6354 0.9687 3117940 ChemDiv3_005246 FC(F)(F)c1cccc(c1)S(=O)(=O)NC2(CC3CC4CC(C3)C2)C4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O11 compound treatment 963722.0 284000.0 0.6 944751.0 251000.0 0.57 0.8286 0.9996 3117941 ChemDiv3_005247 CCn1cc(C=C2C(=O)OC(C)(OC2=O)C(C)(C)C)c3ccccc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O12 compound treatment 1065288.0 386000.0 0.82 1063270.0 369000.0 0.84 1.1714 0.9999 3025417 ChemDiv3_005248 O=C(/C=C/c1ccc2OCOc2c1)/C=C/c3ccc4OCOc4c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O13 compound treatment 932252.0 252000.0 0.54 879193.0 185000.0 0.42 0.676 0.9929 1501347 ChemDiv3_005249 CC1CC1c2ccc(CCC(=O)Nc3ncc(Cc4cccc(Cl)c4)s3)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O14 compound treatment 717073.0 37300.0 0.08 766311.0 72200.0 0.16 0.172 0.9439 3025418 ChemDiv3_005250 CCc1ccc(cc1)N2CN(Cc3ccccc3)CNC2=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O15 compound treatment 870805.0 191000.0 0.4 1004625.0 311000.0 0.71 0.7856 0.9652 1874484 ChemDiv3_005251 Cc1ccc(cc1)S(=O)(=O)NC2CCOC(C)(C)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O16 compound treatment 748163.0 68400.0 0.14 908800.0 215000.0 0.49 0.4477 0.8792 3025419 ChemDiv3_005252 CCCN1CNC(=S)N(C1)c2cc(C)ccc2C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O17 compound treatment 829351.0 150000.0 0.32 898812.0 205000.0 0.47 0.5533 0.9825 3117942 ChemDiv3_005253 CCOc1ccc(cc1OC)C(NC(=O)c2ccco2)NC(=O)c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O18 compound treatment 861427.0 182000.0 0.39 841879.0 148000.0 0.34 0.5099 0.9977 3117943 ChemDiv3_005254 CC1CCCC(C1=O)C2(O)C(=O)Nc3ccccc32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O19 compound treatment 396826.0 -283000.0 -0.6 331043.0 -363000.0 -0.83 -1.0078 -0.9877 3025420 ChemDiv3_005255 Clc1c2C(=O)/C(=C\NC3CCCCC3)/Nc2ccc1Br 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O20 compound treatment 1059517.0 380000.0 0.81 987325.0 293000.0 0.67 1.0406 0.9956 3117944 ChemDiv3_005256 O=C1OC(Nc2ccc(cc2)S(=O)(=O)Nc3ccccn3)c4ccccc14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O21 compound treatment 1016352.0 337000.0 0.71 990994.0 297000.0 0.68 0.9818 0.9996 3025421 ChemDiv3_005257 COC(=O)CC/1SC(=O)N\C1=N/c2ccc(O)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O22 compound treatment 931564.0 252000.0 0.53 910039.0 216000.0 0.49 0.7246 0.9991 3117945 ChemDiv3_005258 CC(=C1C(=O)c2ccccc2C1=O)N3CCC(Cc4ccccc4)CC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O23 mock treatment 802104.0 122000.0 0.26 837469.0 143000.0 0.33 0.4139 0.9936 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 O24 mock treatment 413781.0 -266000.0 -0.56 479287.0 -215000.0 -0.49 -0.7441 -0.9974 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P01 compound treatment 454254.0 -226000.0 -0.48 391501.0 -303000.0 -0.69 -0.8245 -0.9842 1382485 ChemDiv3_005259 O=C(N1N=C(CC1c2ccccc2)c3ccccc3)c4cc5ccccc5oc4=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P02 compound treatment 456044.0 -224000.0 -0.47 448937.0 -245000.0 -0.56 -0.7295 -0.9968 3117946 ChemDiv3_005260 Cc1cc(ccc1Cl)/C(=N/O)/C(C)(C)NO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P03 compound treatment 525402.0 -154000.0 -0.33 516670.0 -177000.0 -0.4 -0.5167 -0.9946 3117947 ChemDiv3_005261 CC1CCN(CC1)C(=S)SCC(=O)n2c(C)c(C)c3ccccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P04 compound treatment 571070.0 -109000.0 -0.23 586120.0 -108000.0 -0.25 -0.3365 -0.9995 3025422 ChemDiv3_005262 COc1ccc(Nc2ccc3nnc(c4ccc(Br)cc4)n3n2)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P05 compound treatment 247743.0 -432000.0 -0.92 249671.0 -444000.0 -1.01 -1.3621 -0.9988 3117948 ChemDiv3_005263 CC1(C)CC(=O)C2=C(C1)N=C3C(C2c4cccc(Br)c4)C(=O)c5ccccc35 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P06 compound treatment 739970.0 60200.0 0.13 724908.0 30800.0 0.07 0.1398 0.9601 3025423 ChemDiv3_005264 CCc1ccc2n(CC)c3nc4ccccc4nc3c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P07 compound treatment 213730.0 -466000.0 -0.99 228271.0 -466000.0 -1.06 -1.4475 -0.9994 3117949 ChemDiv3_005265 COC(=O)C/1=C(C)N(CC2CCCO2)C(=O)\C1=C/c3cc(C)n(c3C)c4ccc(OC)c(Cl)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P08 compound treatment 167486.0 -512000.0 -1.09 157592.0 -537000.0 -1.22 -1.6305 -0.9983 3025424 ChemDiv3_005266 CC(CN1CCCC1)OC(=O)c2cc(cc(c2)C(C)(C)C)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P09 compound treatment 509315.0 -170000.0 -0.36 568859.0 -125000.0 -0.28 -0.4569 -0.993 3117950 ChemDiv3_005267 Cc1cc(ccc1/C=C/2\NC(=O)N(Cc3ccccc3)C2=O)N4CCOCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P10 compound treatment 527374.0 -152000.0 -0.32 564168.0 -130000.0 -0.3 -0.4373 -0.999 3117951 ChemDiv3_005268 CCN1C(=O)c2ccc(cc2C1=O)C(=O)Nc3cc(cc(c3)C(=O)O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P11 compound treatment 566049.0 -114000.0 -0.24 509719.0 -184000.0 -0.42 -0.4669 -0.9655 3025425 ChemDiv3_005269 OC(=O)c1cccc(c1)n2cccc2C=C3C(=O)c4ccccc4C3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P12 compound treatment 136472.0 -543000.0 -1.15 152070.0 -542000.0 -1.23 -1.6858 -0.9994 3118091 ChemDiv3_005270 CCC1(CC)Cc2ccccc2C(=N1)c3cc4ccccc4oc3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P13 compound treatment 515552.0 -164000.0 -0.35 480303.0 -214000.0 -0.49 -0.5899 -0.9866 3025426 ChemDiv3_005271 Cc1cc(I)ccc1n2nc(cc2O)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P14 compound treatment 138402.0 -541000.0 -1.15 185708.0 -508000.0 -1.16 -1.6288 -1.0 3118092 ChemDiv3_005272 COc1ccc(cc1OC)c2c(oc3c(CN4CCCC(C)C4)c(O)ccc3c2=O)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P15 compound treatment 474080.0 -206000.0 -0.44 642022.0 -52100.0 -0.12 -0.3921 -0.8677 3025475 ChemDiv3_005273 O=C(Nc1ccc(CN2CCOCC2)cc1)/C=C/c3ccco3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P16 compound treatment 528194.0 -152000.0 -0.32 735015.0 40900.0 0.09 -0.1614 -0.4826 3025476 ChemDiv3_005274 CCc1cccc(OCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc3nccs3)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P17 compound treatment 566498.0 -113000.0 -0.24 697390.0 3290.0 0.01 -0.1645 -0.6847 3025477 ChemDiv3_005275 C=CCn1c(=O)[nH]c2ccccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P18 compound treatment 729367.0 49600.0 0.11 720988.0 26900.0 0.06 0.1176 0.9667 3025478 ChemDiv3_005276 CN(CC(=O)N1CCc2ccccc2C1)S(=O)(=O)c3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P19 compound treatment 710746.0 31000.0 0.07 770762.0 76700.0 0.17 0.1697 0.911 3025479 ChemDiv3_005277 O=C1S/C(=C\c2cn(Cc3ccccc3)c4ccccc24)/C(=O)N1CN5CCCCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P20 compound treatment 703563.0 23800.0 0.05 796345.0 102000.0 0.23 0.2 0.8409 3025480 ChemDiv3_005278 O=C(CCSc1ccc2ccccc2n1)NCCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P21 compound treatment 659160.0 -20600.0 -0.04 734348.0 40300.0 0.09 0.0338 0.3333 3025481 ChemDiv3_005279 CCCN1C(=O)/C(=C/c2cc(C)n(c2C)c3ccc(Cl)cc3)/NC1=S 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P22 compound treatment 643712.0 -36100.0 -0.08 686543.0 -7550.0 -0.02 -0.0662 -0.8449 3118093 ChemDiv3_005280 O=C(CSc1nnc2scc(c3ccccc3)n12)N4CCCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P23 mock treatment 475528.0 -204000.0 -0.43 537199.0 -157000.0 -0.36 -0.5584 -0.9954 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2015 P24 mock treatment 598949.0 -80800.0 -0.17 471713.0 -222000.0 -0.51 -0.4787 -0.8967 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A01 mock treatment 462247.0 -410000.0 -0.87 531801.0 -297000.0 -0.68 -1.0928 -0.9922 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A02 mock treatment 784323.0 -88200.0 -0.19 816939.0 -12000.0 -0.03 -0.1516 -0.8019 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A03 compound treatment 1022500.0 150000.0 0.32 991340.0 162000.0 0.37 0.4858 0.9972 315 Bio2_000481 CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A04 compound treatment 1153340.0 281000.0 0.6 1004990.0 176000.0 0.4 0.7039 0.9813 85 Bio2_000482 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)NC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A05 compound treatment 94225.0 -778000.0 -1.65 116941.0 -712000.0 -1.62 -2.3114 -1.0 29 Bio2_000483 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NCCCCCCCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A06 compound treatment 890596.0 18000.0 0.04 756282.0 -72700.0 -0.17 -0.0898 -0.5294 302 Bio2_000484 CCCCC[C@H](O)C/C=C/1\[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A07 compound treatment 1046436.0 174000.0 0.37 1279013.0 450000.0 1.02 0.9842 0.9049 10 Bio2_000485 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N[C@H](C)CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A08 compound treatment 1197778.0 325000.0 0.69 1253197.0 424000.0 0.96 1.1696 0.9864 262 Bio2_000486 CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A09 compound treatment 1118201.0 246000.0 0.52 1300928.0 472000.0 1.07 1.127 0.9449 100 Bio2_000487 C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)C[C@H](O)C3=C)/CCC[C@]12C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A10 compound treatment 1085471.0 213000.0 0.45 1194561.0 366000.0 0.83 0.9069 0.9588 1000034 Bio2_000488 CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A11 compound treatment 1171494.0 299000.0 0.63 975372.0 146000.0 0.33 0.6835 0.9548 148 Bio2_000489 CCCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCCCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A12 compound treatment 1228492.0 356000.0 0.75 1170299.0 341000.0 0.78 1.0823 0.9999 122 Bio2_000490 C(c1c[nH]c2ccccc12)c3c[nH]c4ccccc34 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A13 compound treatment 1172357.0 300000.0 0.64 1160296.0 331000.0 0.75 0.9821 0.9964 150 Bio2_000491 CCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A14 compound treatment 1180814.0 308000.0 0.65 1344175.0 515000.0 1.17 1.2904 0.962 31 Bio2_000492 CCCCCCCCCCCCCCC[C@H](O)[C@@H](N)CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A15 compound treatment 1116975.0 244000.0 0.52 1362827.0 534000.0 1.21 1.2247 0.9279 171 Bio2_000493 CCCCCCCC/C=C\CCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCC/C=C\CCCCCCCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A16 compound treatment 1030594.0 158000.0 0.34 1134087.0 305000.0 0.69 0.7274 0.9442 33 Bio2_000494 CCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@H](O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A17 compound treatment 1065309.0 193000.0 0.41 1240546.0 412000.0 0.94 0.9506 0.931 141 Bio2_000495 CCCCC/C=C\CC1OC1C/C=C\C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A18 compound treatment 879206.0 6650.0 0.01 759850.0 -69100.0 -0.16 -0.1011 -0.6411 34 Bio2_000496 CCCCCCCCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@H](O)c2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A19 compound treatment 1140354.0 268000.0 0.57 1135114.0 306000.0 0.7 0.8936 0.9949 1000003 Bio2_000497 CCCCC/C=C\C[C@@H](O)/C=C/C=C\C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A20 compound treatment 1101554.0 229000.0 0.49 1107988.0 279000.0 0.63 0.7919 0.9913 223 Bio2_000498 CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A21 compound treatment 659250.0 -213000.0 -0.45 1056934.0 228000.0 0.52 0.0468 0.068 46 Bio2_000499 CCCCC/C=C\C[C@H](O)/C=C/C=C\C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A22 compound treatment 602748.0 -270000.0 -0.57 872557.0 43600.0 0.1 -0.3344 -0.576 268 Bio2_000500 CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A23 mock treatment 515633.0 -357000.0 -0.76 435231.0 -394000.0 -0.9 -1.168 -0.9965 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 A24 mock treatment 483325.0 -389000.0 -0.83 468732.0 -360000.0 -0.82 -1.1626 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B01 mock treatment 545518.0 -327000.0 -0.69 706545.0 -122000.0 -0.28 -0.687 -0.9196 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B02 mock treatment 779992.0 -92600.0 -0.2 933873.0 105000.0 0.24 0.0299 0.0969 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B03 compound treatment 195190.0 -677000.0 -1.44 185944.0 -643000.0 -1.46 -2.0491 -1.0 1000048 Bio2_000501 CC(C)COCC(CN(Cc1ccccc1)c2ccccc2)N3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B04 compound treatment 133333.0 -739000.0 -1.57 147683.0 -681000.0 -1.55 -2.2034 -1.0 2139 Bio2_000502 O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4[C@@H]([C@H]32)[C@@H]1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B05 compound treatment 139380.0 -733000.0 -1.55 145184.0 -684000.0 -1.55 -2.1983 -1.0 32 Bio2_000503 C/C(=C/1\C(=O)C2C3C(Cc4cccc5[nH]cc3c45)C(C)(C)N2C1=O)/O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B06 compound treatment 433935.0 -439000.0 -0.93 590858.0 -238000.0 -0.54 -1.0403 -0.9668 3000451 Bio2_000504 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5cccc(O)c5cc4Cn3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B07 compound treatment 528942.0 -344000.0 -0.73 573897.0 -255000.0 -0.58 -0.9251 -0.9936 3000787 Bio2_000505 [O-][N+](=O)c1ccc(cc1)c2ccc(/C=N/N3CC(=O)NC3=O)o2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B08 compound treatment 138133.0 -734000.0 -1.56 142748.0 -686000.0 -1.56 -2.2041 -1.0 2127 Bio2_000506 CC1(C)CCC2=C(O1)c3ccccc3C(=O)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B09 compound treatment 967315.0 94800.0 0.2 1088088.0 259000.0 0.59 0.5586 0.8975 35 Bio2_000507 CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B10 compound treatment 400169.0 -472000.0 -1.0 258603.0 -570000.0 -1.3 -1.625 -0.9918 3103826 Bio2_000508 C/C/1=C\CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B11 compound treatment 746542.0 -126000.0 -0.27 675020.0 -154000.0 -0.35 -0.4364 -0.9911 3103827 Bio2_000509 N/C(=N\C(=O)c1nc(Cl)c(N)nc1N)/NCc2ccc(Cl)cc2Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B12 compound treatment 120207.0 -752000.0 -1.59 129991.0 -699000.0 -1.59 -2.2515 -1.0 1907748 Bio2_000510 CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B13 compound treatment 1028390.0 156000.0 0.33 1098720.0 270000.0 0.61 0.6673 0.9579 3000452 Bio2_000511 *CCN1C(=O)[C@H](OC(=O)C)[C@@H](Sc2ccccc12)c3ccc(OC)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B14 compound treatment 140986.0 -732000.0 -1.55 130946.0 -698000.0 -1.59 -2.2188 -0.9999 3000453 Bio2_000512 C[C@@H]1CC2OC(=O)C(=C)C2[C@H](O)[C@@]3(C)[C@H]1C=CC3=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B15 compound treatment 873874.0 1320.0 0.0 1084205.0 255000.0 0.58 0.4123 0.7105 357 Bio2_000513 Cc1cccc(CCN2CCC(CC2)C(=O)c3ccc(NS(=O)(=O)C)cc3)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B16 compound treatment 870498.0 -2060.0 0.0 1044752.0 216000.0 0.49 0.3438 0.7008 1000105 Bio2_000514 CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B17 compound treatment 231002.0 -642000.0 -1.36 187875.0 -641000.0 -1.46 -1.9923 -0.9994 39 Bio2_000515 Nc1c(S(=O)C(F)(F)F)c(C#N)nn1c2c(Cl)cc(cc2Cl)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B18 compound treatment 942679.0 70100.0 0.15 1045103.0 216000.0 0.49 0.4526 0.8816 1907749 Bio2_000516 CCOC(=O)CN1C(=O)CC(C[C@@H](O)C2C[C@@H](C)C[C@H](C)C2=O)CC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B19 compound treatment 919677.0 47100.0 0.1 945027.0 116000.0 0.26 0.2572 0.9116 359 Bio2_000517 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)C(=O)NCC2CCCCN2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B20 compound treatment 149560.0 -723000.0 -1.53 124364.0 -705000.0 -1.6 -2.2165 -0.9998 1907750 Bio2_000518 CC[C@@H]1/C=C(\C)/C[C@H](C)C[C@H](OC)[C@H]2O[C@](O)([C@H](C)C[C@@H]2OC)C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@H](C)[C@@H](O)CC1=O)\C(=C\[C@@H]4CC[C@@H](O)[C@@H](C4)OC)\C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B21 compound treatment 902460.0 29900.0 0.06 938765.0 110000.0 0.25 0.2214 0.8594 41 Bio2_000519 OC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B22 compound treatment 365680.0 -507000.0 -1.07 332259.0 -497000.0 -1.13 -1.5583 -0.9997 2349 Bio2_000520 CC12CC=C3C(CCC4=CC(=O)C=CC43C)C2CC[C@@H]1C(=O)CN5CCN(CC5)c6cc(nc(n6)N7CCCC7)N8CCCC8 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B23 mock treatment 859441.0 -13100.0 -0.03 822690.0 -6260.0 -0.01 -0.0297 -0.9517 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 B24 mock treatment 482419.0 -390000.0 -0.83 519368.0 -310000.0 -0.7 -1.0825 -0.9968 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C01 mock treatment 914685.0 42100.0 0.09 810386.0 -18600.0 -0.04 0.0333 0.3371 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C02 mock treatment 1014095.0 142000.0 0.3 906344.0 77400.0 0.18 0.3366 0.9677 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C03 compound treatment 1056393.0 184000.0 0.39 925816.0 96900.0 0.22 0.4313 0.9635 87 Bio2_000521 CCCCC/C=C\C[C@H](OO)/C=C/C=C\C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C04 compound treatment 1166943.0 294000.0 0.62 976508.0 148000.0 0.34 0.6785 0.9576 264 Bio2_000522 CC/C=C\C/C=C\C/C=C\CCCCCCCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C05 compound treatment 1134460.0 262000.0 0.56 911965.0 83000.0 0.19 0.5261 0.8971 301 Bio2_000523 COCCCCCCCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C06 compound treatment 1045745.0 173000.0 0.37 976038.0 147000.0 0.33 0.4961 0.9989 233 Bio2_000524 CCCCCCCCCCC/C=C\C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C07 compound treatment 1113593.0 241000.0 0.51 1000714.0 172000.0 0.39 0.6375 0.9912 61 Bio2_000525 CCCCC[C@H](O)/C=C/C=C\CCCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C08 compound treatment 1122212.0 250000.0 0.53 918537.0 89600.0 0.2 0.5183 0.9139 256 Bio2_000526 CCCCC/C=C\C/C=C\CCCCCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C09 compound treatment 1133497.0 261000.0 0.55 1069098.0 240000.0 0.55 0.7772 1.0 90 Bio2_000527 CCCCC[C@H](OO)/C=C/C=C\CCCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C10 compound treatment 1170965.0 298000.0 0.63 1000006.0 171000.0 0.39 0.7223 0.9727 221 Bio2_000528 CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C11 compound treatment 959530.0 87000.0 0.18 1154839.0 326000.0 0.74 0.6543 0.8569 304 Bio2_000529 CCCCC[C@H](O)CC[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C12 compound treatment 1043128.0 171000.0 0.36 1021829.0 193000.0 0.44 0.5658 0.9954 260 Bio2_000530 CC/C=C\C/C=C\C/C=C\CCCCCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C13 compound treatment 892475.0 19900.0 0.04 854790.0 25800.0 0.06 0.0714 0.9869 1000009 Bio2_000531 C/C(=C\C=C\C(=C/C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C14 compound treatment 992244.0 120000.0 0.25 989963.0 161000.0 0.37 0.4383 0.984 1000007 Bio2_000532 CCCCCCCCCCCCCCCCOC[C@@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C15 compound treatment 1063116.0 191000.0 0.4 962356.0 133000.0 0.3 0.5001 0.99 149 Bio2_000533 CCCCC(=O)/C=C/C=C\CCCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C16 compound treatment 1236431.0 364000.0 0.77 949370.0 120000.0 0.27 0.739 0.9029 55 Bio2_000534 CC(=CCC/C(=C/CC/C(=C/CSCC(=O)O)/C)/C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C17 compound treatment 1046404.0 174000.0 0.37 975336.0 146000.0 0.33 0.4959 0.9987 143 Bio2_000535 CCCCCC1OC1C/C=C\C/C=C\C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C18 compound treatment 1023159.0 151000.0 0.32 1035522.0 207000.0 0.47 0.5578 0.9823 217 Bio2_000536 O[C@@H](COc1cccc(c1)C(F)(F)F)/C=C/[C@H]2[C@H](O)C[C@H](O)[C@@H]2C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C19 compound treatment 822613.0 -49900.0 -0.11 883913.0 55000.0 0.12 0.0135 0.0824 50 Bio2_000537 CCCCC[C@H](O)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C20 compound treatment 843956.0 -28600.0 -0.06 851797.0 22800.0 0.05 -0.0061 -0.077 231 Bio2_000538 CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C21 compound treatment 764279.0 -108000.0 -0.23 836818.0 7870.0 0.02 -0.1497 -0.65 89 Bio2_000539 CCCCC[C@H](OO)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C22 compound treatment 866471.0 -6090.0 -0.01 896580.0 67600.0 0.15 0.0996 0.6455 92 Bio2_000540 CCCCC/C=C\CC1OC1CCCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C23 mock treatment 694004.0 -179000.0 -0.38 749150.0 -79800.0 -0.18 -0.396 -0.9433 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 C24 mock treatment 575611.0 -297000.0 -0.63 464206.0 -365000.0 -0.83 -1.0315 -0.9908 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D01 mock treatment 919044.0 46500.0 0.1 813791.0 -15200.0 -0.03 0.0453 0.434 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D02 mock treatment 1026307.0 154000.0 0.33 932964.0 104000.0 0.24 0.3977 0.9876 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D03 compound treatment 506039.0 -367000.0 -0.78 631985.0 -197000.0 -0.45 -0.8661 -0.9657 43 Bio2_000541 Fc1ccc(cc1)C(N2CCN(C/C=C/c3ccccc3)CC2)c4ccc(F)cc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D04 compound treatment 539601.0 -333000.0 -0.71 484401.0 -345000.0 -0.78 -1.053 -0.9986 1531 Bio2_000542 O=c1n([se]c2ccccc12)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D05 compound treatment 474583.0 -398000.0 -0.84 508038.0 -321000.0 -0.73 -1.1125 -0.9974 3104253 Bio2_000543 CC(CCCN1CCC2(CC1)N(C)CNC2=O)c3ccc(F)cc3.Fc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D06 compound treatment 915216.0 42700.0 0.09 939354.0 110000.0 0.25 0.2414 0.9049 1875 Bio2_000544 FC(F)(F)c1ccccc1n2ccnc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D07 compound treatment 645641.0 -227000.0 -0.48 629969.0 -199000.0 -0.45 -0.66 -0.9995 3000569 Bio2_000545 Cc1cc(C(=O)c2ccccc2Cc3ccccc3)c(C)[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D08 compound treatment 867890.0 -4670.0 -0.01 954567.0 126000.0 0.29 0.1949 0.6822 2372 Bio2_000546 COc1cc(ccc1OC(F)F)c2ccc(=O)[nH]n2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D09 compound treatment 890090.0 17500.0 0.04 939587.0 111000.0 0.25 0.2041 0.8029 70 Bio2_000547 CCCCC[C@H](O)CC(=O)CCc1ccc(O)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D10 compound treatment 914457.0 41900.0 0.09 1086636.0 258000.0 0.59 0.4771 0.8051 3000570 Bio2_000548 CCCNc1ccccc1c2nc3[nH]nnc3c(=O)[nH]2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D11 compound treatment 956813.0 84300.0 0.18 937356.0 108000.0 0.25 0.3006 0.9875 72 Bio2_000549 Cc1cnc(cn1)C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D12 compound treatment 1452780.0 580000.0 1.23 1186791.0 358000.0 0.81 1.4451 0.9799 3000571 Bio2_000550 *C1=C[C@]2(CC)CCCN3CCc4c(C32)n1c5ccccc45 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D13 compound treatment 1152982.0 280000.0 0.59 972637.0 144000.0 0.33 0.6514 0.9602 74 Bio2_000551 COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D14 compound treatment 150489.0 -722000.0 -1.53 189472.0 -639000.0 -1.45 -2.1105 -0.9997 2337 Bio2_000552 COc1cc2CCn3c(cc(=Nc4c(C)cc(C)cc4C)n(C)c3=O)-c2cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D15 compound treatment 957900.0 85300.0 0.18 1079075.0 250000.0 0.57 0.53 0.8882 76 Bio2_000553 CC1(C)[C@@H](O)C[C@@H]2[C@]1(O)[C@H](O)C[C@@]3(C[C@@](C)(O)C4CC[C@H]3[C@@]2(C)O)[C@@H]4O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D16 compound treatment 929822.0 57300.0 0.12 887831.0 58900.0 0.13 0.1805 0.9988 1907751 Bio2_000554 CN/C(=N\c1ccc(cc1)C2=NNC(=O)CC2C)/NC#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D17 compound treatment 893799.0 21200.0 0.05 921835.0 92900.0 0.21 0.1812 0.839 78 Bio2_000555 C[C@]1(Cc2cc(OCC(=O)O)c(Cl)c(Cl)c2C1=O)C3CCCC3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D18 compound treatment 958723.0 86200.0 0.18 912820.0 83900.0 0.19 0.264 0.9998 1000092 Bio2_000556 COc1ccc(cc1OC2CCCC2)C3CNC(=O)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D19 compound treatment 947746.0 75200.0 0.16 925836.0 96900.0 0.22 0.2685 0.9874 3103683 Bio2_000557 COc1ccccc1.CS[C@H](C)[C@H](OC(=O)C)C(=O)N(C)CCN(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D20 compound treatment 896149.0 23600.0 0.05 834032.0 5080.0 0.01 0.0435 0.8481 2270 Bio2_000558 CCCCOc1cc(CC2CNC(=O)N2)ccc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D21 compound treatment 790829.0 -81700.0 -0.17 828012.0 -940.0 0.0 -0.124 -0.7158 362 Bio2_000559 CCN(CC)CC(=O)Nc1c(C)cccc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D22 compound treatment 714875.0 -158000.0 -0.33 656634.0 -172000.0 -0.39 -0.5134 -0.9969 1865 Bio2_000560 Clc1cccc(Nc2nnc(c3ccccc3)c4ccccc24)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D23 mock treatment 639706.0 -233000.0 -0.49 609451.0 -220000.0 -0.5 -0.7019 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 D24 mock treatment 556931.0 -316000.0 -0.67 558365.0 -271000.0 -0.62 -0.9081 -0.9991 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E01 mock treatment 809537.0 -63000.0 -0.13 777643.0 -51300.0 -0.12 -0.177 -0.9977 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E02 mock treatment 900118.0 27600.0 0.06 895504.0 66600.0 0.15 0.1483 0.9144 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E03 compound treatment 869208.0 -3350.0 -0.01 884712.0 55800.0 0.13 0.0846 0.6665 308 Bio2_000561 CCCCC/C=C/C=C/1\[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E04 compound treatment 1042424.0 170000.0 0.36 1096205.0 267000.0 0.61 0.6843 0.9688 94 Bio2_000562 CCCCCC1OC1C/C=C\CCCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E05 compound treatment 1068846.0 196000.0 0.42 1086973.0 258000.0 0.59 0.709 0.9859 147 Bio2_000563 CCCCCC(=O)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E06 compound treatment 1136312.0 264000.0 0.56 1043388.0 214000.0 0.49 0.7401 0.9977 1000018 Bio2_000564 CCCCC/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E07 compound treatment 1120010.0 247000.0 0.52 1032321.0 203000.0 0.46 0.6979 0.998 259 Bio2_000565 CCCCC(C)(C)[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E08 compound treatment 1158533.0 286000.0 0.61 996828.0 168000.0 0.38 0.6986 0.9751 3000590 Bio2_000566 **(*)S[C@H](/C=C/C=C/C=C\C/C=C\CCCCC)[C@@H](O)CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E09 compound treatment 1055325.0 183000.0 0.39 1054050.0 225000.0 0.51 0.6359 0.9906 272 Bio2_000567 OC(=O)CCCCCCCCCCCCCCCC#C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E10 compound treatment 1022982.0 150000.0 0.32 1084664.0 256000.0 0.58 0.6366 0.96 3000609 Bio2_000568 *C(=O)[C@H](CS)NS[C@H](/C=C/C=C/C=C\C/C=C\CCCCC)[C@@H](O)CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E11 compound treatment 1121890.0 249000.0 0.53 1175108.0 346000.0 0.79 0.9303 0.9812 300 Bio2_000569 O[C@@H](CCc1ccccc1)/C=C/[C@H]2[C@H](O)CC(=O)[C@@H]2C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E12 compound treatment 1146284.0 274000.0 0.58 1281394.0 452000.0 1.03 1.1377 0.9633 3000610 Bio2_000570 *[C@H](/C=C/C=C/C=C\C/C=C\CCCCC)[C@@H](O)CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E13 compound treatment 1102180.0 230000.0 0.49 1187958.0 359000.0 0.82 0.9214 0.9695 109 Bio2_000571 CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E14 compound treatment 1129872.0 257000.0 0.55 1215345.0 386000.0 0.88 1.0069 0.9737 22 Bio2_000572 CCCCC/C=C\C/C=C\CCCCCCCC(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E15 compound treatment 1060991.0 188000.0 0.4 1071861.0 243000.0 0.55 0.673 0.9874 179 Bio2_000573 CCCCCCCCCCCCCCCCOC[C@H](CO)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E16 compound treatment 933649.0 61100.0 0.13 1136689.0 308000.0 0.7 0.5863 0.824 270 Bio2_000574 CCCCC/C=C\C/C=C\CCCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E17 compound treatment 1019016.0 146000.0 0.31 1121997.0 293000.0 0.67 0.6907 0.9396 81 Bio2_000575 CCCCCCCCCCCCCCCCOCC(COP(=O)(O)OCC[N+](C)(C)C)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E18 compound treatment 1113780.0 241000.0 0.51 1116081.0 287000.0 0.65 0.8232 0.9927 229 Bio2_000576 CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E19 compound treatment 1002253.0 130000.0 0.27 1081348.0 252000.0 0.57 0.6002 0.9432 183 Bio2_000577 CCCCCCCCCCCCCCCCOCC(CO)OC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E20 compound treatment 1090659.0 218000.0 0.46 1095132.0 266000.0 0.61 0.7549 0.9912 186 Bio2_000578 CCCCC[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E21 compound treatment 1087954.0 215000.0 0.46 1119227.0 290000.0 0.66 0.7895 0.9838 181 Bio2_000579 CCCCCCCCCCCCCCCCOCC(CO)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E22 compound treatment 1154464.0 282000.0 0.6 1053488.0 225000.0 0.51 0.7836 0.9969 3000631 Bio2_000580 *P(=O)OC[C@H](NC(=O)CCCCCCCCCCCCCCC)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E23 mock treatment 938505.0 65900.0 0.14 933196.0 104000.0 0.24 0.2664 0.9683 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 E24 mock treatment 1030116.0 158000.0 0.33 764179.0 -64800.0 -0.15 0.1321 0.3618 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F01 mock treatment 931364.0 58800.0 0.12 932336.0 103000.0 0.24 0.2544 0.956 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F02 mock treatment 1054662.0 182000.0 0.39 895286.0 66300.0 0.15 0.3796 0.9159 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F03 compound treatment 142226.0 -730000.0 -1.55 185682.0 -643000.0 -1.46 -2.1289 -0.9996 80 Bio2_000581 CN(C)C(=O)C(CCN1CCC(O)(CC1)c2ccc(Cl)cc2)(c3ccccc3)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F04 compound treatment 665881.0 -207000.0 -0.44 766764.0 -62200.0 -0.14 -0.4098 -0.8901 3000632 Bio2_000582 *CCNS(=O)(=O)c1cccc2c(Cl)cccc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F05 compound treatment 434408.0 -438000.0 -0.93 473667.0 -355000.0 -0.81 -1.228 -0.9976 372 Bio2_000583 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2cc(OC)c(OC)c(OC)c2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F06 compound treatment 1035014.0 162000.0 0.34 1092509.0 264000.0 0.6 0.6672 0.9654 47 Bio2_000584 CC(=CCC/C(=C/CC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)/C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F07 compound treatment 1088272.0 216000.0 0.46 1044895.0 216000.0 0.49 0.6705 0.9994 82 Bio2_000585 Nc1cc(nc(N)[n+]1[O-])N2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F08 compound treatment 132061.0 -740000.0 -1.57 103012.0 -726000.0 -1.65 -2.2771 -0.9997 3000633 Bio2_000586 Cc1ccc(C(=O)*2****o2)c3nc4c(C(=O)*5****o5)c(N)c(=O)c(C)c4oc13 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F09 compound treatment 956882.0 84300.0 0.18 1223277.0 394000.0 0.9 0.7603 0.8317 84 Bio2_000587 Nc1cc(nc(N)[n+]1OS(=O)(=O)O)N2CCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F10 compound treatment 953215.0 80700.0 0.17 941206.0 112000.0 0.26 0.3014 0.981 1907752 Bio2_000588 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCc1ccc(O)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F11 compound treatment 271034.0 -602000.0 -1.28 282884.0 -546000.0 -1.24 -1.7796 -0.9999 86 Bio2_000589 COC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCCN(C)Cc3ccccc3)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F12 compound treatment 235245.0 -637000.0 -1.35 270623.0 -558000.0 -1.27 -1.8529 -0.9995 331 Bio2_000590 COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F13 compound treatment 901555.0 29000.0 0.06 1218946.0 390000.0 0.89 0.6704 0.7543 110 Bio2_000591 COC(=O)C1=C(C)NC(=C(C1c2ccccc2[N+](=O)[O-])C(=O)OC)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F14 compound treatment 1148773.0 276000.0 0.59 1043815.0 215000.0 0.49 0.7595 0.9959 333 Bio2_000592 NC(=S)/C(=C/c1ccc(O)c(O)c1)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F15 compound treatment 1190653.0 318000.0 0.67 1196132.0 367000.0 0.83 1.0671 0.9944 112 Bio2_000593 OC(=O)c1cccnc1Nc2cccc(c2)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F16 compound treatment 1010273.0 138000.0 0.29 1087900.0 259000.0 0.59 0.6227 0.9476 203 Bio2_000594 NC(=C(C#N)C#N)/C(=C/c1ccc2[nH]ccc2c1)/C#N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F17 compound treatment 206579.0 -666000.0 -1.41 142639.0 -686000.0 -1.56 -2.1017 -0.9988 907431 Bio2_000595 COC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCCCN3CCC(CC3)(c4ccccc4)c5ccccc5)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F18 compound treatment 1095167.0 223000.0 0.47 900738.0 71800.0 0.16 0.4491 0.8994 3 Bio2_000596 Oc1ccc(/C=C(\C#N)/C(=O)NCc2ccccc2)cc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F19 compound treatment 444910.0 -428000.0 -0.91 434240.0 -395000.0 -0.9 -1.2756 -1.0 115 Bio2_000597 COCCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC(C)C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F20 compound treatment 876381.0 3820.0 0.01 880534.0 51600.0 0.12 0.0887 0.7542 208 Bio2_000598 CC(C)(C)c1cc(/C=C(\C#N)/C(=S)N)cc(c1O)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F21 compound treatment 458506.0 -414000.0 -0.88 503614.0 -325000.0 -0.74 -1.1437 -0.9964 117 Bio2_000599 CCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F22 compound treatment 590507.0 -282000.0 -0.6 666741.0 -162000.0 -0.37 -0.6836 -0.973 2413 Bio2_000600 CC(C)CC(NC(=O)CNC(=O)C(C)(C)NC(=O)C(NC(=O)C(C)(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C1CCCN1C(=O)C(C)(C)NC(=O)C)C(C)C)C(=O)NC(C)(C)C(=O)N2CCCC2C(=O)NC(C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CO)Cc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F23 mock treatment 1078571.0 206000.0 0.44 916906.0 88000.0 0.2 0.4502 0.9373 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 F24 mock treatment 1084523.0 212000.0 0.45 823122.0 -5830.0 -0.01 0.3084 0.686 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G01 mock treatment 896639.0 24100.0 0.05 728387.0 -101000.0 -0.23 -0.1256 -0.536 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G02 mock treatment 796001.0 -76600.0 -0.16 866185.0 37200.0 0.08 -0.0549 -0.2999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G03 compound treatment 1078934.0 206000.0 0.44 924464.0 95500.0 0.22 0.4629 0.9478 83 Bio2_000601 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G04 compound treatment 900705.0 28100.0 0.06 896432.0 67500.0 0.15 0.1507 0.9153 191 Bio2_000602 CCCc1c(O)c(ccc1OCCCCc2nnn[nH]2)C(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G05 compound treatment 1048409.0 176000.0 0.37 937565.0 109000.0 0.25 0.4382 0.98 173 Bio2_000603 CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](CO)OC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G06 compound treatment 1032197.0 160000.0 0.34 912578.0 83600.0 0.19 0.3737 0.9628 3000641 Bio2_000604 *CCOP(=O)(O)OC[C@H](O)COCCCCCCCCCCCCCCCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G07 compound treatment 992760.0 120000.0 0.25 885581.0 56600.0 0.13 0.2712 0.95 177 Bio2_000605 CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC/C=C\C/C=C\CCCCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G08 compound treatment 952465.0 79900.0 0.17 1020954.0 192000.0 0.44 0.4285 0.915 111 Bio2_000606 CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G09 compound treatment 924638.0 52100.0 0.11 1018602.0 190000.0 0.43 0.383 0.8604 175 Bio2_000607 CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G10 compound treatment 1058973.0 186000.0 0.4 1188624.0 360000.0 0.82 0.8577 0.9443 36 Bio2_000608 CCCCCCCCCCCCCC(=O)N[C@H](C)[C@@H](O)c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G11 compound treatment 1248897.0 376000.0 0.8 1232049.0 403000.0 0.92 1.2122 0.9976 102 Bio2_000609 C[C@H](CC[C@@H](O)C(C)(C)O)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)CCC3=C)/CCC[C@]12C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G12 compound treatment 683796.0 -189000.0 -0.4 664998.0 -164000.0 -0.37 -0.5465 -0.9994 1000002 Bio2_000610 CCCCCCCCCCCCCC(=O)N[C@@H](C)[C@H](O)c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G13 compound treatment 1140398.0 268000.0 0.57 1095246.0 266000.0 0.61 0.8296 0.9995 98 Bio2_000611 C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)CCC3=C)/CCC[C@]12C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G14 compound treatment 1226004.0 353000.0 0.75 1232494.0 404000.0 0.92 1.1786 0.9949 227 Bio2_000612 CCCCCCCC/C=C\C/C=C\C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G15 compound treatment 1169824.0 297000.0 0.63 981946.0 153000.0 0.35 0.6916 0.9608 118 Bio2_000613 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OC(CO)CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G16 compound treatment 775118.0 -97400.0 -0.21 819963.0 -8990.0 -0.02 -0.1605 -0.7733 8 Bio2_000614 CCCCCCCC/C=C\C/C=C\C/C=C\CCCC(=O)NCCO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G17 compound treatment 1234841.0 362000.0 0.77 880361.0 51400.0 0.12 0.6257 0.8054 276 Bio2_000615 CCCCCCCCCCCCCCC(F)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G18 compound treatment 1042329.0 170000.0 0.36 981643.0 153000.0 0.35 0.5 0.9998 136 Bio2_000616 COC(C)(C)CCCC(C)C/C=C/C(=C/C(=O)O)/C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G19 compound treatment 926267.0 53700.0 0.11 775149.0 -53800.0 -0.12 -0.006 -0.0358 274 Bio2_000617 CCCCCCCCCCCCC(O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G20 compound treatment 835578.0 -37000.0 -0.08 805510.0 -23400.0 -0.05 -0.0931 -0.9823 310 Bio2_000618 CCCCC(C)(O)C/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G21 compound treatment 756778.0 -116000.0 -0.25 808853.0 -20100.0 -0.05 -0.2059 -0.8246 130 Bio2_000619 C/C(=C\C=C\C(=C\C(=O)Nc1ccc(O)cc1)\C)/C=C/C2=C(C)CCCC2(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G22 compound treatment 773436.0 -99100.0 -0.21 821803.0 -7150.0 -0.02 -0.1601 -0.7595 309 Bio2_000620 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G23 mock treatment 708429.0 -164000.0 -0.35 728461.0 -100000.0 -0.23 -0.4076 -0.9792 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 G24 mock treatment 564359.0 -308000.0 -0.65 636675.0 -192000.0 -0.44 -0.7711 -0.9809 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H01 mock treatment 729763.0 -143000.0 -0.3 579217.0 -250000.0 -0.57 -0.6155 -0.9566 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H02 mock treatment 1005505.0 133000.0 0.28 993041.0 164000.0 0.37 0.4631 0.9904 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H03 compound treatment 1055536.0 183000.0 0.39 992149.0 163000.0 0.37 0.5367 0.9998 119 Bio2_000621 OC(=O)c1ccccc1Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H04 compound treatment 1041697.0 169000.0 0.36 1259110.0 430000.0 0.98 0.9451 0.9073 556 Bio2_000622 COc1cc2ncc(nc2cc1OC)c3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H05 compound treatment 1041393.0 169000.0 0.36 992892.0 164000.0 0.37 0.5166 0.9998 3001877 Bio2_000623 OC(=O)c1cc(O)ccc1NCCCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H06 compound treatment 1309472.0 437000.0 0.93 993931.0 165000.0 0.38 0.9202 0.9208 3001878 Bio2_000624 Cc1[nH]c(=O)c([N+]#[C-])cc1c2ccncc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H07 compound treatment 730134.0 -142000.0 -0.3 799910.0 -29000.0 -0.07 -0.2602 -0.8418 2450 Bio2_000625 Oc1ccc(cc1n2c(=O)[nH]c3cc(ccc23)C(F)(F)F)C(F)(F)F 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H08 compound treatment 419145.0 -453000.0 -0.96 446622.0 -382000.0 -0.87 -1.2943 -0.9987 2080829 Bio2_000626 OCC1(CO)N2CCC(CC2)C1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H09 compound treatment 1141846.0 269000.0 0.57 964703.0 136000.0 0.31 0.6219 0.9583 124 Bio2_000627 CC(C)(O)[C@H]1O[C@H]2CC[C@]3(C)[C@]4(C)[C@H](Cc5c4[nH]c6ccccc56)CC[C@@]3(O)C2=CC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H10 compound treatment 1536739.0 664000.0 1.41 1506217.0 677000.0 1.54 2.0844 0.999 1907753 Bio2_000628 CC[C@@H]1[C@H](C)C[C@@H]2[C@H]3C[C@H]4CCC(=O)C5=C(O)[C@H](CCCNC(=O)/C=C\C[C@@H]4[C@H]3C=C[C@@H]12)NC5=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H11 compound treatment 1504926.0 632000.0 1.34 1742644.0 914000.0 2.08 2.4168 0.9775 126 Bio2_000629 CC1(C)Oc2ccc(C#N)cc2[C@@H](OC3=CC(=O)CC3)[C@@H]1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H12 compound treatment 1062752.0 190000.0 0.4 1352836.0 524000.0 1.19 1.1273 0.8965 354 Bio2_000630 Nc1ccc2C(=O)NC(=O)c3cccc1c32 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H13 compound treatment 1068271.0 196000.0 0.41 925543.0 96600.0 0.22 0.4487 0.9558 128 Bio2_000631 CC(=C)[C@H]1O[C@H]2CC[C@]3(C)[C@]4(C)[C@@H](CC[C@@]3(O)[C@@]52O[C@@H]5[C@H]1O)[C@@H]6OC(C)(C)[C@H]7C[C@@H]8C(=C)Cc9c(Cl)cc%10[nH]c4c6c%10c9[C@@]87O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H14 compound treatment 1461294.0 589000.0 1.25 1471013.0 642000.0 1.46 1.9147 0.997 445 Bio2_000632 NC(=O)c1cccc(N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H15 compound treatment 232737.0 -640000.0 -1.36 259218.0 -570000.0 -1.3 -1.875 -0.9997 2474 Bio2_000633 Nc1nc(N)c(nc1Cl)C(=O)NC(=N)Nc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H16 compound treatment 138842.0 -734000.0 -1.56 109375.0 -720000.0 -1.64 -2.2567 -0.9997 1907754 Bio2_000634 CO[C@H]1C[C@H](C)CC2=C(NCC=C)C(=O)C=C(NC(=O)/C(=C/C=C\[C@H](OC)[C@@H](OC(=O)N)/C(=C/[C@H](C)[C@H]1O)/C)/C)C2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H17 compound treatment 1186657.0 314000.0 0.67 1143284.0 314000.0 0.71 0.9762 0.9994 153 Bio2_000635 CC1=CC=C(CC1)N(CC2=NCCN2)c3cccc(O)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H18 compound treatment 118766.0 -754000.0 -1.6 112384.0 -717000.0 -1.63 -2.2819 -1.0 3001880 Bio2_000636 CC(=O)O[C@@H]1[C@@H](O)CN[C@@H]1Cc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H19 compound treatment 1041604.0 169000.0 0.36 869295.0 40300.0 0.09 0.3183 0.8604 3001155 Bio2_000637 CC1(C)NC(=O)NC1=O.c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H20 compound treatment 143647.0 -729000.0 -1.55 111805.0 -717000.0 -1.63 -2.2456 -0.9996 154 Bio2_000638 C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H]1CC[C@H]3C[C@@H]4C[C@@]32CC[C@]4(O)CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H21 compound treatment 252607.0 -620000.0 -1.31 197141.0 -632000.0 -1.44 -1.9451 -0.999 156 Bio2_000639 Fc1ccc(cc1)C(CCCN2CCC(CC2)n3c(=O)[nH]c4ccccc34)c5ccc(F)cc5Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H22 compound treatment 769467.0 -103000.0 -0.22 824692.0 -4260.0 -0.01 -0.1614 -0.7377 401 Bio2_000640 COc1cccc2c1cc([N+](=O)[O-])c3c(cc4OCOc4c23)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H23 mock treatment 770733.0 -102000.0 -0.22 801428.0 -27500.0 -0.06 -0.1969 -0.876 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 H24 mock treatment 643022.0 -230000.0 -0.49 663623.0 -165000.0 -0.38 -0.6099 -0.9919 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I01 mock treatment 878444.0 5890.0 0.01 732911.0 -96000.0 -0.22 -0.1456 -0.6656 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I02 mock treatment 1134919.0 262000.0 0.56 1011929.0 183000.0 0.42 0.6875 0.9898 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I03 compound treatment 1039426.0 167000.0 0.35 1144734.0 316000.0 0.72 0.7578 0.9468 299 Bio2_000641 CCCCCCCCCCOCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I04 compound treatment 965095.0 92500.0 0.2 1104924.0 276000.0 0.63 0.5824 0.8859 184 Bio2_000642 CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SCC(NC(=O)C)C(=O)O)[C@@H](O)CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I05 compound treatment 1173440.0 301000.0 0.64 1107170.0 278000.0 0.63 0.8983 1.0 13 Bio2_000643 CCCCC/C=C\C/C=C\C/C=C\C=C\[C@@H](O)CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I06 compound treatment 1539575.0 667000.0 1.41 1172975.0 344000.0 0.78 1.5529 0.961 14 Bio2_000644 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I07 compound treatment 1175053.0 302000.0 0.64 1223853.0 395000.0 0.9 1.0883 0.9864 64 Bio2_000645 CCCCC/C=C\C/C=C\C/C=C\C=C\[C@H](CCCC(=O)O)OO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I08 compound treatment 1498708.0 626000.0 1.33 1283786.0 455000.0 1.03 1.6698 0.9924 123 Bio2_000646 CCCCC/C=C\C/C=C\CCCCCCCC(=O)NCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I09 compound treatment 1684952.0 812000.0 1.72 1666028.0 837000.0 1.9 2.5635 0.9988 137 Bio2_000647 CCCCC/C=C\C/C=C\C/C=C\CC1OC1CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I10 compound treatment 1556785.0 684000.0 1.45 1409777.0 581000.0 1.32 1.9594 0.9989 40 Bio2_000648 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I11 compound treatment 1321380.0 449000.0 0.95 1665854.0 837000.0 1.9 2.0182 0.9487 146 Bio2_000649 CCCCCC#CCC#CCC#CCC#CCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I12 compound treatment 1454307.0 582000.0 1.23 1435037.0 606000.0 1.38 1.8464 0.9985 66 Bio2_000650 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I13 compound treatment 1190365.0 318000.0 0.67 1273161.0 444000.0 1.01 1.1905 0.9806 144 Bio2_000651 CCCCCCCCC#CCC#CCC#CCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I14 compound treatment 1187142.0 315000.0 0.67 1729943.0 901000.0 2.05 1.92 0.8913 69 Bio2_000652 CCCCCCCC/C=C\CCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I15 compound treatment 1235236.0 363000.0 0.77 1279030.0 450000.0 1.02 1.2672 0.9901 145 Bio2_000653 CCCCC/C=C\C/C=C\C/C=C\C=C\C(=O)CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I16 compound treatment 1423585.0 551000.0 1.17 1233159.0 404000.0 0.92 1.4758 0.9929 318 Bio2_000654 CCCCCCCCCCCCCCCC(=O)NCCO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I17 compound treatment 1341624.0 469000.0 0.99 1666110.0 837000.0 1.9 2.049 0.9542 120 Bio2_000655 O=Cc1c2[nH]c3ccccc3c2cc4[nH]c5ccccc5c14 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I18 compound treatment 1213563.0 341000.0 0.72 1257023.0 428000.0 0.97 1.1994 0.9893 114 Bio2_000656 CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)O)OC(=O)CCCCCCCCCCCCCCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I19 compound treatment 1065409.0 193000.0 0.41 1094071.0 265000.0 0.6 0.7153 0.9821 257 Bio2_000657 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC(=O)CCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I20 compound treatment 1186306.0 314000.0 0.67 1184220.0 355000.0 0.81 1.0415 0.9953 190 Bio2_000658 CCCCC[C@H](O)/C=C/[C@H]1C=CC(=O)[C@@H]1CCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I21 compound treatment 1060068.0 188000.0 0.4 1051718.0 223000.0 0.51 0.6392 0.9928 258 Bio2_000659 CCCCCCCCCCC/C=C\C(C)(C)/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I22 compound treatment 908738.0 36200.0 0.08 1079637.0 251000.0 0.57 0.4572 0.7951 212 Bio2_000660 CCCCC[C@H](O)/C=C/[C@H]1C=CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I23 mock treatment 1002479.0 130000.0 0.28 1119438.0 290000.0 0.66 0.6618 0.9248 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 I24 mock treatment 1006785.0 134000.0 0.28 943235.0 114000.0 0.26 0.3849 0.999 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J01 mock treatment 1179165.0 307000.0 0.65 950780.0 122000.0 0.28 0.6555 0.9277 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J02 mock treatment 1218254.0 346000.0 0.73 1219805.0 391000.0 0.89 1.1466 0.9954 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J03 compound treatment 1091771.0 219000.0 0.46 988691.0 160000.0 0.36 0.5854 0.9926 3104408 Bio2_000661 CC(N/C(=N\C#N)/Nc1ccncc1)C(C)(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J04 compound treatment 1191189.0 319000.0 0.68 1275497.0 447000.0 1.02 1.1955 0.9804 1907755 Bio2_000662 COCc1nc2n(CC(C)C)c(=O)n(C)c(=O)c2[nH]1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J05 compound treatment 1053280.0 181000.0 0.38 1160749.0 332000.0 0.75 0.8043 0.9507 2431 Bio2_000663 CCN(CC)CCNC(=O)c1ccc(N)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J06 compound treatment 1047862.0 175000.0 0.37 1181698.0 353000.0 0.8 0.8299 0.9389 1907756 Bio2_000664 Clc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J07 compound treatment 125330.0 -747000.0 -1.58 138378.0 -691000.0 -1.57 -2.2303 -1.0 3104409 Bio2_000665 CCCNCC(O)COc1ccccc1.CC(=O)CCc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J08 compound treatment 1628487.0 756000.0 1.6 1329818.0 501000.0 1.14 1.9384 0.986 155 Bio2_000666 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC[C@@H](NC[C@@H](N)CS)C(C)C)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J09 compound treatment 126209.0 -746000.0 -1.58 166722.0 -662000.0 -1.51 -2.1834 -0.9997 161 Bio2_000667 COc1ccc2nccc(C(O)[C@H]3CC4CC[C@@H]3CC4C=C)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J10 compound treatment 1430527.0 558000.0 1.18 1481824.0 653000.0 1.48 1.886 0.9937 361 Bio2_000668 CC(C)(c1ccc(OCC2CO2)cc1)c3ccc(OCC4CO4)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J11 compound treatment 134186.0 -738000.0 -1.57 162284.0 -667000.0 -1.52 -2.1786 -0.9999 1000050 Bio2_000669 COc1ccc2nccc([C@@H](O)[C@@H]3CC4CC[C@@H]3CC4C=C)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J12 compound treatment 106895.0 -766000.0 -1.62 123204.0 -706000.0 -1.6 -2.2823 -1.0 3103962 Bio2_000670 CO[C@H]1/C=C/C=C(\C)/C[C@@H](C)[C@H](O)[C@H](C)/C=C(\C)/C=C(\OC)/C(=O)O[C@@H]1[C@@H](C)[C@@H](O)[C@H](C)[C@H]2C[C@@H](O)[C@H](C)[C@H](O2)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J13 compound treatment 1720373.0 848000.0 1.8 1511832.0 683000.0 1.55 2.3687 0.9973 907369 Bio2_000671 CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J14 compound treatment 1468987.0 596000.0 1.26 1637969.0 809000.0 1.84 2.1947 0.9833 3103963 Bio2_000672 CC(=O)OCOC(=O)CNc1ccccc1OCCOc2ccccc2NCC(=O)OCOC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J15 compound treatment 1646758.0 774000.0 1.64 1574537.0 746000.0 1.7 2.3592 0.9999 3103964 Bio2_000673 CC(C)[C@]1(O)[C@@H](OC(=O)c2ccc[nH]2)[C@]3(O)[C@]4(O)[C@]1(C)[C@]5(O)C[C@@]3(C)[C@@]6(O)CC[C@H](C)[C@@H](O)[C@]46O5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J16 compound treatment 1255341.0 383000.0 0.81 1424713.0 596000.0 1.35 1.5316 0.97 3103618 Bio2_000674 Cc1ccc2N=C3N(CCC3(O)C(=O)c2c1)c4ccccc4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J17 compound treatment 228208.0 -644000.0 -1.37 205937.0 -623000.0 -1.42 -1.9675 -0.9998 165 Bio2_000675 OC(COc1cccc2[nH]c(C#N)cc12)CN3CCN(CC3)C(c4ccccc4)c5ccccc5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J18 compound treatment 1284121.0 412000.0 0.87 1434706.0 606000.0 1.38 1.5908 0.9757 3001881 Bio2_000676 */C=C(/CC(=O)O)\C=C\[C@@H](C)C\C=C\CC/C=C/C=C\CC/C(=C\C=C(\*)/C)/C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J19 compound treatment 138342.0 -734000.0 -1.56 113419.0 -716000.0 -1.63 -2.2509 -0.9998 390 Bio2_000677 COc1ccc(CCCOC(Cn2ccnc2)c3ccc(OC)cc3)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J20 compound treatment 937431.0 64900.0 0.14 1008077.0 179000.0 0.41 0.3852 0.8962 1000439 Bio2_000678 CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4ccc(I)cc4)ncnc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J21 compound treatment 114958.0 -758000.0 -1.61 121653.0 -707000.0 -1.61 -2.2728 -1.0 193 Bio2_000679 COc1cc2CCN(C)[C@H]3Cc4ccc(OC)c(Oc5ccc(C[C@@H]6N(C)CCc7cc(OC)c(Oc(c1OC)c32)cc67)cc5)c4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J22 compound treatment 123554.0 -749000.0 -1.59 105433.0 -724000.0 -1.64 -2.2859 -0.9998 3104702 Bio2_000680 C[C@H]1CCC/C=C/C2C[C@H](O)C[C@H]2[C@H](O)/C=C/C(=O)O1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J23 mock treatment 887100.0 14500.0 0.03 1106458.0 278000.0 0.63 0.4679 0.7408 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 J24 mock treatment 946281.0 73700.0 0.16 950745.0 122000.0 0.28 0.3063 0.9634 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K01 mock treatment 988035.0 115000.0 0.24 750403.0 -78500.0 -0.18 0.0468 0.1545 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K02 mock treatment 1044173.0 172000.0 0.36 1051685.0 223000.0 0.51 0.6153 0.9868 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K03 compound treatment 1157852.0 285000.0 0.6 1135402.0 306000.0 0.7 0.9203 0.9975 139 Bio2_000681 CCCCC/C=C\C/C=C\CC1OC1C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K04 compound treatment 1032896.0 160000.0 0.34 1032397.0 203000.0 0.46 0.5674 0.9885 214 Bio2_000682 CCCCC[C@H](O)/C=C/C1=C(CCCCCCC(=O)O)C(=O)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K05 compound treatment 1134276.0 262000.0 0.55 1074678.0 246000.0 0.56 0.7874 1.0 1000033 Bio2_000683 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@H]1C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K06 compound treatment 1172689.0 300000.0 0.64 1001463.0 173000.0 0.39 0.7272 0.973 216 Bio2_000684 CCCCC[C@H](O)/C=C/C1=C(C/C=C\CCCC(=O)O)C(=O)CC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K07 compound treatment 1095222.0 223000.0 0.47 1109835.0 281000.0 0.64 0.7853 0.9889 57 Bio2_000685 CCCCC/C=C\C=C\[C@@H](O)CCCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K08 compound treatment 946160.0 73600.0 0.16 999127.0 170000.0 0.39 0.3839 0.9203 218 Bio2_000686 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@@H](O)CC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K09 compound treatment 904981.0 32400.0 0.07 1119834.0 291000.0 0.66 0.5162 0.7764 88 Bio2_000687 CCCCC/C=C\C=C\[C@H](CCCCCCCC(=O)O)OO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K10 compound treatment 988189.0 116000.0 0.25 1080359.0 251000.0 0.57 0.5775 0.9286 220 Bio2_000688 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K11 compound treatment 1222859.0 350000.0 0.74 1435289.0 606000.0 1.38 1.4999 0.9579 45 Bio2_000689 CCCCCCCC/C=C\CCCCCCCC(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K12 compound treatment 1150663.0 278000.0 0.59 1372004.0 543000.0 1.23 1.2899 0.9428 222 Bio2_000690 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K13 compound treatment 1228465.0 356000.0 0.75 1140682.0 312000.0 0.71 1.0347 0.9995 1000028 Bio2_000691 CCCCC[C@H](O)/C=C/[C@H]1[C@@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K14 compound treatment 1165719.0 293000.0 0.62 1555405.0 726000.0 1.65 1.6073 0.9108 226 Bio2_000692 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K15 compound treatment 1112335.0 240000.0 0.51 1145541.0 317000.0 0.72 0.8684 0.9855 1000027 Bio2_000693 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H](O)[C@@H]1C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K16 compound treatment 1092618.0 220000.0 0.47 1077233.0 248000.0 0.56 0.729 0.9955 224 Bio2_000694 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K17 compound treatment 1375503.0 503000.0 1.07 1045392.0 216000.0 0.49 1.1019 0.9383 1000008 Bio2_000695 C/C(=C/C=C/C(=C/C(=O)O)/C)/C=C/C1=C(C)CCCC1(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K18 compound treatment 1119697.0 247000.0 0.52 1065681.0 237000.0 0.54 0.751 0.9999 3184 Bio2_000696 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H]2O/C(=C\CCCC(=O)O)/C[C@H]12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K19 compound treatment 955790.0 83200.0 0.18 993684.0 165000.0 0.37 0.3896 0.941 47 Bio2_000697 CC(=CCC/C(=C/CC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)/C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K20 compound treatment 849301.0 -23300.0 -0.05 910653.0 81700.0 0.19 0.0965 0.502 267 Bio2_000698 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K21 compound treatment 914034.0 41500.0 0.09 936116.0 107000.0 0.24 0.2345 0.9052 266 Bio2_000699 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K22 compound treatment 1079287.0 207000.0 0.44 929631.0 101000.0 0.23 0.4718 0.9541 104 Bio2_000700 C/C(=C\C=C\C(=C\C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K23 mock treatment 1082606.0 210000.0 0.45 946237.0 117000.0 0.27 0.5034 0.9699 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 K24 mock treatment 609982.0 -263000.0 -0.56 738347.0 -90600.0 -0.21 -0.5393 -0.9086 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L01 mock treatment 1081113.0 209000.0 0.44 1059648.0 231000.0 0.52 0.6835 0.9964 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L02 mock treatment 1059128.0 187000.0 0.4 1147088.0 318000.0 0.72 0.7911 0.9597 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L03 compound treatment 486681.0 -386000.0 -0.82 568730.0 -260000.0 -0.59 -0.9968 -0.9873 194 Bio2_000701 CCCCCCCC(=O)O[C@@H]1[C@@H](OC(=O)/C(=C\C)/C)C(=C2[C@@H]3OC(=O)[C@@](C)(O)[C@@]3(O)[C@H](C[C@](C)(OC(=O)C)[C@@H]12)OC(=O)CCC)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L04 compound treatment 1075577.0 203000.0 0.43 924961.0 96000.0 0.22 0.4587 0.9505 407 Bio2_000702 [O-][N+](=O)c1cccc2c(Br)n[nH]c12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L05 compound treatment 453074.0 -419000.0 -0.89 500364.0 -329000.0 -0.75 -1.1571 -0.9962 392 Bio2_000703 CCN(CC)CCCCCCCOC(=O)c1cc(OC)c(OC)c(OC)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L06 compound treatment 903043.0 30500.0 0.06 785228.0 -43700.0 -0.1 -0.0246 -0.2074 3103965 Bio2_000704 Nc1ncnc2n(C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3O)c(Br)nc12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L07 compound treatment 1295173.0 423000.0 0.9 1304404.0 475000.0 1.08 1.3979 0.9956 196 Bio2_000705 Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CCCCCC2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L08 compound treatment 1038534.0 166000.0 0.35 1080986.0 252000.0 0.57 0.654 0.9726 3103966 Bio2_000706 NC1=NC2C(N=C(Br)N2C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3O)C(=O)N1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L09 compound treatment 996342.0 124000.0 0.26 882422.0 53500.0 0.12 0.2715 0.9388 198 Bio2_000707 CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L10 compound treatment 1619696.0 747000.0 1.58 1203984.0 375000.0 0.85 1.7229 0.9578 404 Bio2_000708 CCCCNc1cc(cc(c1Oc2ccccc2)S(=O)(=O)N)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L11 compound treatment 1079511.0 207000.0 0.44 1166009.0 337000.0 0.77 0.8521 0.965 3103746 Bio2_000709 C1CCC(CC1)/N=C(\NC2C3CC4CC(C3)CC2C4)/N5CCOCC5 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L12 compound treatment 1531659.0 659000.0 1.4 1575296.0 746000.0 1.7 2.1879 0.9953 3001884 Bio2_000710 CCNC(=O)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)n2cnc3c(N)ncnc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L13 compound treatment 1159527.0 287000.0 0.61 1142443.0 313000.0 0.71 0.9342 0.9969 396 Bio2_000711 CN([C@H]1CCCC[C@@H]1N2CCCC2)C(=O)Cc3ccc(Cl)c(Cl)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L14 compound treatment 1043778.0 171000.0 0.36 1217012.0 388000.0 0.88 0.8805 0.923 373 Bio2_000712 CC(/C=C/c1cccc(Oc2ccc(F)cc2)c1)N(O)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L15 compound treatment 290670.0 -582000.0 -1.23 222463.0 -606000.0 -1.38 -1.8473 -0.9985 1000056 Bio2_000713 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L16 compound treatment 958714.0 86200.0 0.18 1051004.0 222000.0 0.5 0.4861 0.9055 3103967 Bio2_000714 CCCNC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N2CCC[C@H]2C(=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L17 compound treatment 983209.0 111000.0 0.23 965293.0 136000.0 0.31 0.3851 0.9905 200 Bio2_000715 COc1ccc(cc1OC)C(=O)OC2CC[C@@]3(C)C4CCC5[C@@]3(C[C@@]6(O)C7CN8CC(C)CCC8[C@@](C)(O)[C@@]7(O)[C@@H](O)C[C@@]56O)O[C@@]42O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L18 compound treatment 912234.0 39700.0 0.08 1144012.0 315000.0 0.72 0.566 0.7847 1907757 Bio2_000716 Oc1ccc(NC2=C(C(=O)NC2=O)c3ccccc3[N+](=O)[O-])cc1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L19 compound treatment 952886.0 80300.0 0.17 1139325.0 310000.0 0.71 0.6194 0.8533 202 Bio2_000717 COc1ccc(CCN(C)CCc2ccc(OC)c(OC)c2)cc1OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L20 compound treatment 176898.0 -696000.0 -1.47 158702.0 -670000.0 -1.52 -2.1203 -0.9999 3103968 Bio2_000718 CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L21 compound treatment 996799.0 124000.0 0.26 976785.0 148000.0 0.34 0.4239 0.9927 3104544 Bio2_000719 CC(O)(C(=O)Nc1ccccc1)C(F)(F)F.CS(=O)(=O)c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L22 compound treatment 742262.0 -130000.0 -0.28 762875.0 -66100.0 -0.15 -0.3015 -0.959 125 Bio2_000720 COc1cc(O)c2c(=O)c(OC)c(CC(C)OC(=O)Oc3ccc(O)cc3)c4c5c(CC(C)OC(=O)c6ccccc6)c(OC)c(=O)c7c(O)cc(OC)c(c1c24)c75 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L23 mock treatment 1050019.0 177000.0 0.38 1035260.0 206000.0 0.47 0.5977 0.994 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 L24 mock treatment 772722.0 -99800.0 -0.21 788935.0 -40000.0 -0.09 -0.214 -0.9289 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M01 mock treatment 989315.0 117000.0 0.25 919893.0 90900.0 0.21 0.3212 0.996 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M02 mock treatment 1085670.0 213000.0 0.45 968096.0 139000.0 0.32 0.5432 0.9848 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M03 compound treatment 1055570.0 183000.0 0.39 964839.0 136000.0 0.31 0.4928 0.9936 53 Bio2_000721 CC(=CCC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M04 compound treatment 1009879.0 137000.0 0.29 951517.0 123000.0 0.28 0.4029 0.9998 189 Bio2_000722 CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M05 compound treatment 1190645.0 318000.0 0.67 983641.0 155000.0 0.35 0.7255 0.9539 51 Bio2_000723 CC(=CCC/C(=C/CC/C(=C/CC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)/C)/C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M06 compound treatment 1020258.0 148000.0 0.31 945298.0 116000.0 0.26 0.4085 0.9965 49 Bio2_000724 COC(=O)[C@@H](N)CSC/C=C(\C)/CC/C=C(\C)/CCC=C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M07 compound treatment 1082708.0 210000.0 0.45 921553.0 92600.0 0.21 0.4639 0.9414 116 Bio2_000725 Cc1c(nn(c1c2ccc(I)cc2)c3ccc(Cl)cc3Cl)C(=O)NN4CCCCC4 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M08 compound treatment 942462.0 69900.0 0.15 1004464.0 176000.0 0.4 0.3869 0.909 1000032 Bio2_000726 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)CO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M09 compound treatment 1096201.0 224000.0 0.47 969900.0 141000.0 0.32 0.5618 0.9818 132 Bio2_000727 CC1(C)CCC(C)(C)c2cc(ccc21)C(=O)Nc3ccc(cc3)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M10 compound treatment 1172184.0 300000.0 0.64 903785.0 74800.0 0.17 0.5695 0.866 3103969 Bio2_000728 OC(=O)CCC/C=C\CC1C(CNNC(=O)Nc2ccccc2)C3CCC1O3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M11 compound treatment 833805.0 -38800.0 -0.08 841377.0 12400.0 0.03 -0.0381 -0.4388 2 Bio2_000729 CCCCC/C=C\C/C=C\CCCCCCCC(=O)NCCO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M12 compound treatment 1288674.0 416000.0 0.88 1093145.0 264000.0 0.6 1.0485 0.9825 3001885 Bio2_000730 CCCCCc1cc(O)c2C3C=C(CC[C@H]3C(C)(C)Oc2c1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M13 compound treatment 728628.0 -144000.0 -0.31 818871.0 -10100.0 -0.02 -0.232 -0.7581 4 Bio2_000731 CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)NCCO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M14 compound treatment 1002203.0 130000.0 0.27 996833.0 168000.0 0.38 0.4642 0.987 134 Bio2_000732 C/C(=C\c1ccc(cc1)C(=O)O)/c2ccc3c(c2)C(C)(C)CCC3(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M15 compound treatment 828432.0 -44100.0 -0.09 817827.0 -11100.0 -0.03 -0.084 -0.8672 316 Bio2_000733 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M16 compound treatment 1094647.0 222000.0 0.47 940400.0 111000.0 0.25 0.5121 0.9578 261 Bio2_000734 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@H]2CO[C@@H]1C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M17 compound treatment 618398.0 -254000.0 -0.54 710757.0 -118000.0 -0.27 -0.571 -0.9484 6 Bio2_000735 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)NCCO 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M18 compound treatment 920280.0 47700.0 0.1 1033239.0 204000.0 0.46 0.4 0.8414 3103970 Bio2_000736 CCCCC/C=C\CC(O)/C=C/c1cccc(CC(O)CCCCO)n1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M19 compound treatment 866220.0 -6340.0 -0.01 832879.0 3930.0 0.01 -0.0032 -0.1976 20 Bio2_000737 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M20 compound treatment 1024514.0 152000.0 0.32 844000.0 15000.0 0.03 0.252 0.7778 18 Bio2_000738 Cc1c(C(=O)c2ccc3ccccc3c2)c4cccc5OC[C@@H](CN6CCOCC6)n1c54 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M21 compound treatment 1116953.0 244000.0 0.52 907292.0 78300.0 0.18 0.4923 0.8986 225 Bio2_000739 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M22 compound treatment 1014154.0 142000.0 0.3 839882.0 10900.0 0.02 0.2298 0.763 138 Bio2_000740 Cc1cccc(Nc2cc(Cl)nc(SCC(=O)O)n2)c1C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M23 mock treatment 917477.0 44900.0 0.1 817791.0 -11200.0 -0.03 0.0494 0.5012 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 M24 mock treatment 654743.0 -218000.0 -0.46 564763.0 -264000.0 -0.6 -0.7512 -0.9916 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N01 mock treatment 901809.0 29300.0 0.06 925406.0 96500.0 0.22 0.1989 0.8728 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N02 mock treatment 1040513.0 168000.0 0.36 999440.0 170000.0 0.39 0.5259 0.9991 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N03 compound treatment 1296784.0 424000.0 0.9 1099318.0 270000.0 0.61 1.0706 0.9828 1002014 Bio2_000741 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)CCl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N04 compound treatment 144009.0 -729000.0 -1.54 167922.0 -661000.0 -1.5 -2.1548 -0.9999 3103971 Bio2_000742 COC[C@H]([C@@H](O)[C@@H](O)C(=O)NCC[C@@H](C)c1nc(/C=C/C[C@H]2OC3(C[C@H](O)[C@H]2C)OC([C@@H](C[C@@H](O)[C@@H](C)[C@@H](O)[C@@H](C)/C=C(\C)/C(=C/C=C/C(=C\C#N)/C)/C)OC)[C@@H](OP(=O)(O)O)C3(C)C)co1)N(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N05 compound treatment 1271443.0 399000.0 0.85 932189.0 103000.0 0.23 0.7639 0.8705 2041 Bio2_000743 OC(=O)CNC(=O)C(CS)Cc1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N06 compound treatment 1408725.0 536000.0 1.14 1369925.0 541000.0 1.23 1.6734 0.9992 3001887 Bio2_000744 CC[C@@]1(O)C(=O)OCc2c1cc3Cc4nc5ccccc5cc4-n3c2=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N07 compound treatment 893719.0 21200.0 0.04 808997.0 -20000.0 -0.05 -4.0E-4 -0.0056 831924 Bio2_000745 O=C[C@@H]1CCCN1C(=O)[C@@H]2CCCN2C(=O)OCc3ccccc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N08 compound treatment 170887.0 -702000.0 -1.49 202633.0 -626000.0 -1.42 -2.0587 -0.9998 363 Bio2_000746 CC12C3CCC(O3)C2(C)C(=O)OC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N09 compound treatment 627708.0 -245000.0 -0.52 580037.0 -249000.0 -0.57 -0.7672 -0.9991 1907758 Bio2_000747 CCC(C)[C@H](NS(=O)(=O)c1cccc2ccccc12)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N10 compound treatment 1134675.0 262000.0 0.56 1002140.0 173000.0 0.39 0.6713 0.9858 446 Bio2_000748 COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N11 compound treatment 1304569.0 432000.0 0.92 993995.0 165000.0 0.38 0.9129 0.9224 1891 Bio2_000749 Clc1oc(=O)c2ccccc2c1Cl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N12 compound treatment 1094906.0 222000.0 0.47 945067.0 116000.0 0.26 0.52 0.9625 377 Bio2_000750 Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc3ccc(Cl)cc3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N13 compound treatment 111442.0 -761000.0 -1.61 144153.0 -685000.0 -1.56 -2.2419 -0.9998 1907759 Bio2_000751 CC(C)[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)OC(C)(C)C)C(C)C)C=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N14 compound treatment 1258727.0 386000.0 0.82 1090438.0 261000.0 0.59 0.9993 0.9877 379 Bio2_000752 O[C@H]1CCN2C[C@H](O)[C@@H](O)[C@H](O)[C@@H]12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N15 compound treatment 272516.0 -600000.0 -1.27 278973.0 -550000.0 -1.25 -1.7837 -1.0 2060 Bio2_000753 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N16 compound treatment 499158.0 -373000.0 -0.79 600093.0 -229000.0 -0.52 -0.9277 -0.9793 3103975 Bio2_000754 CCCN(CCC)c1nc(N2CCCCC2)c3nc(nc(N4CCCCC4)c3n1)N(CCC)CCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N17 compound treatment 1131703.0 259000.0 0.55 908172.0 79200.0 0.18 0.5158 0.8922 1907760 Bio2_000755 C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)CCl 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N18 compound treatment 559072.0 -313000.0 -0.66 523192.0 -306000.0 -0.7 -0.9615 -0.9997 391 Bio2_000756 Clc1ccc2NC(=O)CSC(c3ccccc3Cl)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N19 compound treatment 518320.0 -354000.0 -0.75 429798.0 -399000.0 -0.91 -1.1727 -0.9956 1907761 Bio2_000757 CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc2ccccc2)C=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N20 compound treatment 1354604.0 482000.0 1.02 1066779.0 238000.0 0.54 1.1049 0.9557 3001890 Bio2_000758 COc1ccc2c(c1)c(OC)[n+](C)c3c2ccc4cc5OCOc5cc43 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N21 compound treatment 123594.0 -749000.0 -1.59 160452.0 -668000.0 -1.52 -2.1974 -0.9998 1907762 Bio2_000759 CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C)C=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N22 compound treatment 260761.0 -612000.0 -1.3 233689.0 -595000.0 -1.35 -1.8741 -0.9998 1907763 Bio2_000760 Oc1ccc(/C=C/C(=O)OCCc2ccccc2)cc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N23 mock treatment 1120879.0 248000.0 0.53 836503.0 7550.0 0.02 0.3844 0.7298 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 N24 mock treatment 754916.0 -118000.0 -0.25 668304.0 -161000.0 -0.37 -0.4346 -0.9827 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O01 mock treatment 970633.0 98100.0 0.21 848333.0 19400.0 0.04 0.1782 0.8383 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O02 mock treatment 1070536.0 198000.0 0.42 1173909.0 345000.0 0.78 0.8513 0.9571 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O03 compound treatment 1072514.0 200000.0 0.42 1120543.0 292000.0 0.66 0.7685 0.9767 73 Bio2_000761 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O04 compound treatment 1049926.0 177000.0 0.38 1150975.0 322000.0 0.73 0.7836 0.952 338 Bio2_000762 Nc1ccncc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O05 compound treatment 1002882.0 130000.0 0.28 1031541.0 203000.0 0.46 0.5211 0.9701 12 Bio2_000763 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)N4CCOCC4)c2c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O06 compound treatment 1096535.0 224000.0 0.47 1127033.0 298000.0 0.68 0.815 0.9849 340 Bio2_000764 CCCCCC(O)CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O07 compound treatment 1142578.0 270000.0 0.57 1048561.0 220000.0 0.5 0.7578 0.9977 305 Bio2_000765 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O08 compound treatment 1129072.0 257000.0 0.54 1073918.0 245000.0 0.56 0.7783 0.9999 1000039 Bio2_000766 CC[C@]1(COC)[C@H](O)C[C@H](OC)[C@@]2(C(C)C)C3C[C@@]4(O)[C@H](OC(=O)c5ccccc5)C3[C@](C[C@H](OC)C12)(OC(=O)C)[C@@H](O)C[C@@H]4OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O09 compound treatment 1103071.0 231000.0 0.49 1094943.0 266000.0 0.6 0.7732 0.9944 307 Bio2_000767 CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(=O)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O10 compound treatment 1177934.0 305000.0 0.65 1007369.0 178000.0 0.41 0.7446 0.9746 24 Bio2_000768 CN(CCc1ccc(Cl)c(Cl)c1)CC(O)COc2ccc(NS(=O)(=O)C)cc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O11 compound treatment 1099938.0 227000.0 0.48 1017583.0 189000.0 0.43 0.6441 0.9983 311 Bio2_000769 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCCCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O12 compound treatment 934319.0 61800.0 0.13 1080139.0 251000.0 0.57 0.4964 0.8472 1000040 Bio2_000770 [N-2]C1(CC2CC3CC(C2)C1)C3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O13 compound treatment 1139695.0 267000.0 0.57 1037064.0 208000.0 0.47 0.735 0.996 313 Bio2_000771 CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(=O)CCCCCCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O14 compound treatment 505927.0 -367000.0 -0.78 663854.0 -165000.0 -0.38 -0.815 -0.9442 1000042 Bio2_000772 NC(=N)NC(=O)c1nc(Cl)c(N)nc1N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O15 compound treatment 1100436.0 228000.0 0.48 1139026.0 310000.0 0.7 0.8401 0.983 271 Bio2_000773 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H]2C/C(=C\CCCC(=O)O)/C[C@H]12 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O16 compound treatment 447178.0 -425000.0 -0.9 548707.0 -280000.0 -0.64 -1.0882 -0.9855 26 Bio2_000774 CCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O17 compound treatment 924289.0 51700.0 0.11 975607.0 147000.0 0.33 0.3133 0.8926 140 Bio2_000775 CC1(COc2ccc(CC3SC(=O)NC3=O)cc2)CCCCC1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O18 compound treatment 1079092.0 207000.0 0.44 1043935.0 215000.0 0.49 0.6552 0.9985 28 Bio2_000776 CNc1ccc2oc(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)c5ccc[nH]5)[C@H](C)C[C@H]4C)nc2c1C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O19 compound treatment 1149153.0 277000.0 0.59 931392.0 102000.0 0.23 0.5793 0.9182 142 Bio2_000777 CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O20 compound treatment 955309.0 82800.0 0.18 805060.0 -23900.0 -0.05 0.0856 0.4663 3103889 Bio2_000778 COC(=O)C1=C(C)NC(=C(O)C1c2ccccc2C(F)(F)F)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O21 compound treatment 1094828.0 222000.0 0.47 954511.0 126000.0 0.29 0.535 0.9712 219 Bio2_000779 O[C@@H](COc1cccc(Cl)c1)/C=C/[C@H]2[C@H](O)C[C@H](O)[C@@H]2C/C=C\CCCC(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O22 compound treatment 266560.0 -606000.0 -1.28 241604.0 -587000.0 -1.34 -1.8527 -0.9998 3103678 Bio2_000780 N/C(=N\C(=O)c1nc(Cl)c(N)nc1N)/NCc2ccccc2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O23 mock treatment 978172.0 106000.0 0.22 1051561.0 223000.0 0.51 0.5162 0.9327 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 O24 mock treatment 1084749.0 212000.0 0.45 843586.0 14600.0 0.03 0.3416 0.7573 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P01 mock treatment 484997.0 -388000.0 -0.82 590196.0 -239000.0 -0.54 -0.9648 -0.9798 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P02 mock treatment 829872.0 -42700.0 -0.09 839776.0 10800.0 0.02 -0.0466 -0.4968 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P03 compound treatment 817381.0 -55200.0 -0.12 883486.0 54500.0 0.12 0.005 0.0291 1907764 Bio2_000781 CCCC[C@@H]1[C@@H](OC(=O)CC(C)C)[C@H](C)OC(=O)[C@@H](NC(=O)c2cccc(NC=O)c2OC)[C@@H](C)OC1=O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P04 compound treatment 1053190.0 181000.0 0.38 916118.0 87200.0 0.2 0.4109 0.953 393 Bio2_000782 CC(C)NCC(O)c1ccc(N)c(C#N)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P05 compound treatment 1058339.0 186000.0 0.39 946073.0 117000.0 0.27 0.4668 0.9818 2090 Bio2_000783 CCOC(=O)C(C#N)C1C(=C(N)Oc2ccc(Br)cc12)C(=O)OCC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P06 compound treatment 868844.0 -3710.0 -0.01 897416.0 68500.0 0.16 0.1045 0.6705 157 Bio2_000784 COC(=O)CC[C@H](NC(=O)CNC(=O)c1ccc(/C=C/C(=O)OC)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P07 compound treatment 1007440.0 135000.0 0.29 1007535.0 179000.0 0.41 0.4893 0.9853 2020 Bio2_000785 CCCCCCCCCCC1=C(C)C(=O)C(=C(OC)C1=O)OC 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P08 compound treatment 1028925.0 156000.0 0.33 1042411.0 213000.0 0.49 0.5776 0.9827 395 Bio2_000786 C(Oc1ccccc1C2CC2)C3=NCCN3 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P09 compound treatment 1097017.0 224000.0 0.48 1124815.0 296000.0 0.67 0.8121 0.9856 3103891 Bio2_000787 CC(=C)C1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P10 compound treatment 1103792.0 231000.0 0.49 1172046.0 343000.0 0.78 0.8982 0.9749 448 Bio2_000788 Clc1cccc(Cl)c1N=C2NCCN2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P11 compound treatment 1176673.0 304000.0 0.64 1145436.0 316000.0 0.72 0.9647 0.9985 1000476 Bio2_000789 C[C@@H](N(C)CC#C)c1ccccc1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P12 compound treatment 1030707.0 158000.0 0.34 1197434.0 368000.0 0.84 0.8295 0.9192 417 Bio2_000790 CN1CCN(CC1)C2=Nc3cc(Cl)ccc3Nc4ccccc24 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P13 compound treatment 1131769.0 259000.0 0.55 1054753.0 226000.0 0.51 0.7516 0.9994 410 Bio2_000791 CC(=N)NCc1cccc(CN)c1 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P14 compound treatment 255646.0 -617000.0 -1.31 200504.0 -628000.0 -1.43 -1.9351 -0.999 3001893 Bio2_000792 COc1ccc(/C=C/C(=O)CC(=O)\C=C\c2cccc(O)c2OC)cc1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P15 compound treatment 1046369.0 174000.0 0.37 1074085.0 245000.0 0.56 0.6546 0.9798 3001894 Bio2_000793 *[C@@H](C[C@@H](C)C[C@H](O)CCCC[C@@H](O)C[C@H](O)[C@H](C)N)[C@H](*)[C@H](C)CCCC.CC(=O)C[C@@H](CC(=O)O)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P16 compound treatment 197230.0 -675000.0 -1.43 179917.0 -649000.0 -1.48 -2.0558 -0.9999 421 Bio2_000794 C[C@H]1C[C@H](C)C(=O)[C@@H](C1)[C@@H](O)CC2CC(=O)NC(=O)C2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P17 compound treatment 1074145.0 202000.0 0.43 957041.0 128000.0 0.29 0.5081 0.9825 2340 Bio2_000795 CC(C)[C@@]12O[C@H]2[C@@H]3O[C@]34[C@]5(O[C@H]5C[C@H]6C7=C(CC[C@@]64C)C(=O)OC7)[C@@H]1O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P18 compound treatment 132675.0 -740000.0 -1.57 186140.0 -643000.0 -1.46 -2.1425 -0.9994 3001895 Bio2_000796 *C1N(C)C(=O)C(*)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C(=O)C(CC)NC(=O)C(C(O)C(C)C/C=C/C)N(C)C(=O)C(*)N(C)C1=O)C(C)C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P19 compound treatment 1065646.0 193000.0 0.41 1059574.0 231000.0 0.52 0.6602 0.9925 1907765 Bio2_000797 Cc1coc-2c1C(=O)C(=O)c3c4CCCC(C)(C)c4ccc23 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P20 compound treatment 984117.0 112000.0 0.24 926019.0 97100.0 0.22 0.3233 0.9994 397 Bio2_000798 CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)c2cccc(Oc3ccccc3)c2 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P21 compound treatment 107377.0 -765000.0 -1.62 91006.0 -738000.0 -1.68 -2.3334 -0.9999 3103893 Bio2_000799 C[C@H]([C@@H]1O[C@@H](C[C@@H]2CC[C@@H](C)[C@@]3(O[C@@](C)(C[C@H]3C)[C@H]4CC[C@](C)(O4)[C@@H]5O[C@H](C[C@@H]5C)[C@H]6O[C@@](O)(CO)[C@H](C)C[C@@H]6C)O2)CC[C@@H]1C)C(=O)O 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P22 compound treatment 1126361.0 254000.0 0.54 1006790.0 178000.0 0.4 0.6664 0.9901 3103894 Bio2_000800 C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@@]42OC(=O)/C=C/[C@H](O)CCC[C@@H](C)C\C=C\[C@H]4[C@H](O)C1=C 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P23 mock treatment 1062980.0 190000.0 0.4 931401.0 102000.0 0.23 0.4502 0.9659 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.2128 P24 mock treatment 760080.0 -112000.0 -0.24 506039.0 -323000.0 -0.73 -0.6877 -0.891 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A01 mock treatment 461850.0 -655000.0 -1.39 -1.389 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A02 mock treatment 725311.0 -392000.0 -0.83 -0.8304 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A03 mock treatment 791973.0 -325000.0 -0.69 -0.6891 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A04 mock treatment 894008.0 -223000.0 -0.47 -0.4728 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A05 mock treatment 881045.0 -236000.0 -0.5 -0.5003 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A06 mock treatment 956292.0 -161000.0 -0.34 -0.3408 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A07 mock treatment 848646.0 -268000.0 -0.57 -0.569 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A08 mock treatment 759898.0 -357000.0 -0.76 -0.7571 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A09 mock treatment 887706.0 -229000.0 -0.49 -0.4862 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A10 mock treatment 907502.0 -210000.0 -0.44 -0.4442 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A11 mock treatment 970698.0 -146000.0 -0.31 -0.3102 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A12 mock treatment 840731.0 -276000.0 -0.59 -0.5858 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A13 mock treatment 836607.0 -280000.0 -0.59 -0.5945 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A14 mock treatment 1006462.0 -111000.0 -0.23 -0.2344 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A15 mock treatment 1044947.0 -72100.0 -0.15 -0.1528 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A16 mock treatment 984946.0 -132000.0 -0.28 -0.28 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A17 mock treatment 917188.0 -200000.0 -0.42 -0.4237 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A18 mock treatment 956362.0 -161000.0 -0.34 -0.3406 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A19 mock treatment 1117947.0 908.0 0.0 0.0019 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A20 mock treatment 954974.0 -162000.0 -0.34 -0.3436 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A21 mock treatment 845757.0 -271000.0 -0.58 -0.5751 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A22 mock treatment 760634.0 -356000.0 -0.76 -0.7556 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A23 mock treatment 506941.0 -610000.0 -1.29 -1.2934 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base A24 mock treatment 441883.0 -675000.0 -1.43 -1.4313 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B01 mock treatment 525468.0 -592000.0 -1.25 -1.2541 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B02 mock treatment 857133.0 -260000.0 -0.55 -0.551 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B03 mock treatment 948788.0 -168000.0 -0.36 -0.3567 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B04 mock treatment 939738.0 -177000.0 -0.38 -0.3759 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B05 mock treatment 970709.0 -146000.0 -0.31 -0.3102 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B06 mock treatment 984842.0 -132000.0 -0.28 -0.2803 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B07 mock treatment 825840.0 -291000.0 -0.62 -0.6173 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B08 mock treatment 905952.0 -211000.0 -0.45 -0.4475 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B09 mock treatment 982634.0 -134000.0 -0.28 -0.2849 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B10 mock treatment 1016725.0 -100000.0 -0.21 -0.2127 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B11 mock treatment 1045895.0 -71100.0 -0.15 -0.1508 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B12 mock treatment 1212907.0 95900.0 0.2 0.2032 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B13 mock treatment 1118340.0 1300.0 0.0 0.0028 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B14 mock treatment 1135848.0 18800.0 0.04 0.0399 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B15 mock treatment 1069772.0 -47300.0 -0.1 -0.1002 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B16 mock treatment 1080845.0 -36200.0 -0.08 -0.0767 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B17 mock treatment 1000451.0 -117000.0 -0.25 -0.2472 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B18 mock treatment 1049882.0 -67200.0 -0.14 -0.1424 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B19 mock treatment 1222537.0 105000.0 0.22 0.2237 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B20 mock treatment 1076065.0 -41000.0 -0.09 -0.0869 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B21 mock treatment 1042188.0 -74900.0 -0.16 -0.1587 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B22 mock treatment 992416.0 -125000.0 -0.26 -0.2642 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B23 mock treatment 795980.0 -321000.0 -0.68 -0.6806 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base B24 mock treatment 490766.0 -626000.0 -1.33 -1.3277 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C01 mock treatment 651442.0 -466000.0 -0.99 -0.987 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C02 mock treatment 857310.0 -260000.0 -0.55 -0.5506 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C03 mock treatment 956552.0 -160000.0 -0.34 -0.3402 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C04 mock treatment 1010551.0 -106000.0 -0.23 -0.2258 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C05 mock treatment 1038846.0 -78200.0 -0.17 -0.1658 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C06 mock treatment 959503.0 -158000.0 -0.33 -0.334 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C07 mock treatment 1055739.0 -61300.0 -0.13 -0.13 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C08 mock treatment 1059301.0 -57700.0 -0.12 -0.1224 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C09 mock treatment 1140181.0 23100.0 0.05 0.0491 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C10 mock treatment 1203666.0 86600.0 0.18 0.1836 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C11 mock treatment 1124083.0 7040.0 0.01 0.0149 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C12 mock treatment 1137925.0 20900.0 0.04 0.0443 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C13 mock treatment 1163094.0 46100.0 0.1 0.0976 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C14 mock treatment 1100788.0 -16300.0 -0.03 -0.0345 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C15 mock treatment 1028975.0 -88100.0 -0.19 -0.1867 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C16 mock treatment 1018327.0 -98700.0 -0.21 -0.2093 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C17 mock treatment 1087561.0 -29500.0 -0.06 -0.0625 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C18 mock treatment 1069473.0 -47600.0 -0.1 -0.1008 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C19 mock treatment 1176477.0 59400.0 0.13 0.126 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C20 mock treatment 1145862.0 28800.0 0.06 0.0611 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C21 mock treatment 936134.0 -181000.0 -0.38 -0.3835 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C22 mock treatment 1017065.0 -100000.0 -0.21 -0.2119 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C23 mock treatment 839302.0 -278000.0 -0.59 -0.5888 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base C24 mock treatment 667212.0 -450000.0 -0.95 -0.9536 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D01 mock treatment 578037.0 -539000.0 -1.14 -1.1427 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D02 mock treatment 766824.0 -350000.0 -0.74 -0.7424 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D03 mock treatment 832821.0 -284000.0 -0.6 -0.6025 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D04 mock treatment 892547.0 -224000.0 -0.48 -0.4759 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D05 mock treatment 831404.0 -286000.0 -0.61 -0.6055 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D06 mock treatment 895018.0 -222000.0 -0.47 -0.4707 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D07 mock treatment 782633.0 -334000.0 -0.71 -0.7089 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D08 mock treatment 882462.0 -235000.0 -0.5 -0.4973 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D09 mock treatment 888852.0 -228000.0 -0.48 -0.4837 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D10 mock treatment 943092.0 -174000.0 -0.37 -0.3688 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D11 mock treatment 1053172.0 -63900.0 -0.14 -0.1354 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D12 mock treatment 1320973.0 204000.0 0.43 0.4323 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D13 mock treatment 1095713.0 -21300.0 -0.05 -0.0452 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D14 mock treatment 1118590.0 1550.0 0.0 0.0033 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D15 mock treatment 1014093.0 -103000.0 -0.22 -0.2182 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D16 mock treatment 1161028.0 44000.0 0.09 0.0933 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D17 mock treatment 1048230.0 -68800.0 -0.15 -0.1459 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D18 mock treatment 999522.0 -118000.0 -0.25 -0.2491 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D19 mock treatment 1025242.0 -91800.0 -0.19 -0.1946 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D20 mock treatment 915374.0 -202000.0 -0.43 -0.4275 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D21 mock treatment 962183.0 -155000.0 -0.33 -0.3283 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D22 mock treatment 908660.0 -208000.0 -0.44 -0.4418 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base D23 mock treatment 892301.0 -225000.0 -0.48 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1010.0014.Base E07 mock treatment 1035210.0 -81800.0 -0.17 -0.1735 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E08 mock treatment 1108097.0 -8940.0 -0.02 -0.019 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E09 mock treatment 1087972.0 -29100.0 -0.06 -0.0616 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E10 mock treatment 1076044.0 -41000.0 -0.09 -0.0869 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E11 mock treatment 1143633.0 26600.0 0.06 0.0564 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E12 mock treatment 1269596.0 153000.0 0.32 0.3234 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E13 mock treatment 1363670.0 247000.0 0.52 0.5228 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E14 mock treatment 1097373.0 -19700.0 -0.04 -0.0417 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E15 mock treatment 1131678.0 14600.0 0.03 0.031 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E16 mock treatment 1096491.0 -20500.0 -0.04 -0.0436 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E17 mock treatment 1188610.0 71600.0 0.15 0.1517 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E18 mock treatment 1155907.0 38900.0 0.08 0.0824 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E19 mock treatment 1157378.0 40300.0 0.09 0.0855 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E20 mock treatment 1089420.0 -27600.0 -0.06 -0.0586 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E21 mock treatment 1012972.0 -104000.0 -0.22 -0.2206 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E22 mock treatment 962755.0 -154000.0 -0.33 -0.3271 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E23 mock treatment 928699.0 -188000.0 -0.4 -0.3993 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base E24 mock treatment 732614.0 -384000.0 -0.81 -0.815 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F01 mock treatment 802322.0 -315000.0 -0.67 -0.6672 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F02 mock treatment 826522.0 -291000.0 -0.62 -0.6159 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F03 mock treatment 900456.0 -217000.0 -0.46 -0.4591 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F04 mock treatment 889005.0 -228000.0 -0.48 -0.4834 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F05 mock treatment 1010058.0 -107000.0 -0.23 -0.2268 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F06 mock treatment 1024870.0 -92200.0 -0.2 -0.1954 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F07 mock treatment 981830.0 -135000.0 -0.29 -0.2866 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F08 mock treatment 1101308.0 -15700.0 -0.03 -0.0333 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F09 mock treatment 1005389.0 -112000.0 -0.24 -0.2367 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F10 mock treatment 1188932.0 71900.0 0.15 0.1524 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F11 mock treatment 1511828.0 395000.0 0.84 0.8369 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F12 mock treatment 1605280.0 488000.0 1.04 1.035 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F13 mock treatment 1335082.0 218000.0 0.46 0.4622 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F14 mock treatment 1501120.0 384000.0 0.81 0.8142 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F15 mock treatment 1332880.0 216000.0 0.46 0.4576 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F16 mock treatment 1477525.0 360000.0 0.76 0.7642 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F17 mock treatment 1370613.0 254000.0 0.54 0.5376 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F18 mock treatment 1113694.0 -3350.0 -0.01 -0.0071 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F19 mock treatment 1120934.0 3890.0 0.01 0.0083 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F20 mock treatment 1054765.0 -62300.0 -0.13 -0.132 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F21 mock treatment 974067.0 -143000.0 -0.3 -0.3031 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F22 mock treatment 1001066.0 -116000.0 -0.25 -0.2459 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F23 mock treatment 847183.0 -270000.0 -0.57 -0.5721 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base F24 mock treatment 658788.0 -458000.0 -0.97 -0.9715 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G01 mock treatment 774828.0 -342000.0 -0.73 -0.7255 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G02 mock treatment 974882.0 -142000.0 -0.3 -0.3014 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G03 mock treatment 954896.0 -162000.0 -0.34 -0.3437 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G04 mock treatment 1117548.0 509.0 0.0 0.0011 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G05 mock treatment 1059149.0 -57900.0 -0.12 -0.1227 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G06 mock treatment 1138659.0 21600.0 0.05 0.0458 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G07 mock treatment 966310.0 -151000.0 -0.32 -0.3195 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G08 mock treatment 1128346.0 11300.0 0.02 0.024 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G09 mock treatment 1252348.0 135000.0 0.29 0.2868 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G10 mock treatment 1335378.0 218000.0 0.46 0.4629 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G11 mock treatment 1135375.0 18300.0 0.04 0.0389 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G12 mock treatment 1212750.0 95700.0 0.2 0.2029 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G13 mock treatment 1515326.0 398000.0 0.84 0.8444 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G14 mock treatment 1374874.0 258000.0 0.55 0.5466 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G15 mock treatment 1208005.0 91000.0 0.19 0.1928 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G16 mock treatment 1365204.0 248000.0 0.53 0.5261 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G17 mock treatment 1175597.0 58600.0 0.12 0.1241 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G18 mock treatment 1118569.0 1530.0 0.0 0.0032 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G19 mock treatment 1197385.0 80300.0 0.17 0.1703 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G20 mock treatment 1140362.0 23300.0 0.05 0.0494 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G21 mock treatment 1197351.0 80300.0 0.17 0.1703 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G22 mock treatment 1080927.0 -36100.0 -0.08 -0.0766 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G23 mock treatment 1070891.0 -46100.0 -0.1 -0.0978 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base G24 mock treatment 666006.0 -451000.0 -0.96 -0.9562 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H01 mock treatment 960830.0 -156000.0 -0.33 -0.3312 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H02 mock treatment 1014645.0 -102000.0 -0.22 -0.2171 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H03 mock treatment 958310.0 -159000.0 -0.34 -0.3365 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H04 mock treatment 1027909.0 -89100.0 -0.19 -0.189 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H05 mock treatment 1079281.0 -37800.0 -0.08 -0.08 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H06 mock treatment 1396499.0 279000.0 0.59 0.5924 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H07 mock treatment 1166970.0 49900.0 0.11 0.1059 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H08 mock treatment 1193742.0 76700.0 0.16 0.1626 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H09 mock treatment 1425654.0 309000.0 0.65 0.6543 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H10 mock treatment 1337781.0 221000.0 0.47 0.468 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H11 mock treatment 1075925.0 -41100.0 -0.09 -0.0872 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H12 mock treatment 1481263.0 364000.0 0.77 0.7721 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H13 mock treatment 1541917.0 425000.0 0.9 0.9007 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H14 mock treatment 1350403.0 233000.0 0.49 0.4947 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H15 mock treatment 1462228.0 345000.0 0.73 0.7318 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H16 mock treatment 1224795.0 108000.0 0.23 0.2284 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H17 mock treatment 1098136.0 -18900.0 -0.04 -0.0401 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H18 mock treatment 1402760.0 286000.0 0.61 0.6057 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H19 mock treatment 1161719.0 44700.0 0.09 0.0947 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H20 mock treatment 1145850.0 28800.0 0.06 0.0611 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H21 mock treatment 1078236.0 -38800.0 -0.08 -0.0823 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H22 mock treatment 1039738.0 -77300.0 -0.16 -0.1639 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H23 mock treatment 1160710.0 43700.0 0.09 0.0926 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base H24 mock treatment 1007226.0 -110000.0 -0.23 -0.2328 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I01 mock treatment 1118321.0 1280.0 0.0 0.0027 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I02 mock treatment 1180099.0 63100.0 0.13 0.1337 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I03 mock treatment 1053386.0 -63700.0 -0.13 -0.1349 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I04 mock treatment 1050273.0 -66800.0 -0.14 -0.1415 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I05 mock treatment 1233480.0 116000.0 0.25 0.2468 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I06 mock treatment 1235233.0 118000.0 0.25 0.2506 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I07 mock treatment 1604888.0 488000.0 1.03 1.0342 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I08 mock treatment 1341046.0 224000.0 0.47 0.4749 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I09 mock treatment 1493598.0 377000.0 0.8 0.7983 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I10 mock treatment 1153914.0 36900.0 0.08 0.0782 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I11 mock treatment 1406207.0 289000.0 0.61 0.613 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I12 mock treatment 1727416.0 610000.0 1.29 1.294 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I13 mock treatment 1272121.0 155000.0 0.33 0.3288 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I14 mock treatment 1561520.0 444000.0 0.94 0.9423 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I15 mock treatment 1284963.0 168000.0 0.36 0.356 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I16 mock treatment 1618066.0 501000.0 1.06 1.0622 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I17 mock treatment 1538114.0 421000.0 0.89 0.8927 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I18 mock treatment 1467820.0 351000.0 0.74 0.7436 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I19 mock treatment 1038426.0 -78600.0 -0.17 -0.1667 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I20 mock treatment 1254587.0 138000.0 0.29 0.2916 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I21 mock treatment 1175354.0 58300.0 0.12 0.1236 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I22 mock treatment 1117730.0 691.0 0.0 0.0015 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I23 mock treatment 1134238.0 17200.0 0.04 0.0365 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base I24 mock treatment 1163924.0 46900.0 0.1 0.0994 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J01 mock treatment 1082687.0 -34400.0 -0.07 -0.0728 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J02 mock treatment 1126794.0 9750.0 0.02 0.0207 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J03 mock treatment 1073620.0 -43400.0 -0.09 -0.092 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J04 mock treatment 1219092.0 102000.0 0.22 0.2163 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J05 mock treatment 1107723.0 -9320.0 -0.02 -0.0198 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J06 mock treatment 1325561.0 209000.0 0.44 0.4421 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J07 mock treatment 1406853.0 290000.0 0.61 0.6144 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J08 mock treatment 1241364.0 124000.0 0.26 0.2636 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J09 mock treatment 1415546.0 299000.0 0.63 0.6328 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J10 mock treatment 1368636.0 252000.0 0.53 0.5334 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J11 mock treatment 1290075.0 173000.0 0.37 0.3668 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J12 mock treatment 1307663.0 191000.0 0.4 0.4041 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J13 mock treatment 1661440.0 544000.0 1.15 1.1541 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J14 mock treatment 1660468.0 543000.0 1.15 1.152 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J15 mock treatment 1384861.0 268000.0 0.57 0.5678 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J16 mock treatment 1624296.0 507000.0 1.08 1.0754 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J17 mock treatment 1050978.0 -66100.0 -0.14 -0.14 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J18 mock treatment 1462316.0 345000.0 0.73 0.732 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J19 mock treatment 1241857.0 125000.0 0.26 0.2646 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J20 mock treatment 1388751.0 272000.0 0.58 0.576 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J21 mock treatment 1098486.0 -18600.0 -0.04 -0.0393 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J22 mock treatment 1120999.0 3960.0 0.01 0.0084 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J23 mock treatment 1001446.0 -116000.0 -0.25 -0.2451 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base J24 mock treatment 1148779.0 31700.0 0.07 0.0673 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K01 mock treatment 652959.0 -464000.0 -0.98 -0.9838 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K02 mock treatment 1023531.0 -93500.0 -0.2 -0.1982 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K03 mock treatment 1149721.0 32700.0 0.07 0.0693 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K04 mock treatment 1183087.0 66000.0 0.14 0.14 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K05 mock treatment 1016237.0 -101000.0 -0.21 -0.2137 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K06 mock treatment 1074390.0 -42600.0 -0.09 -0.0904 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K07 mock treatment 1218054.0 101000.0 0.21 0.2141 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K08 mock treatment 1151150.0 34100.0 0.07 0.0723 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K09 mock treatment 1211221.0 94200.0 0.2 0.1997 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K10 mock treatment 1065537.0 -51500.0 -0.11 -0.1092 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K11 mock treatment 1504559.0 388000.0 0.82 0.8215 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K12 mock treatment 1306800.0 190000.0 0.4 0.4023 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K13 mock treatment 1228989.0 112000.0 0.24 0.2373 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K14 mock treatment 1190325.0 73300.0 0.16 0.1554 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K15 mock treatment 1202041.0 85000.0 0.18 0.1802 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K16 mock treatment 1224234.0 107000.0 0.23 0.2272 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K17 mock treatment 1269547.0 153000.0 0.32 0.3233 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K18 mock treatment 1149269.0 32200.0 0.07 0.0683 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K19 mock treatment 1168594.0 51600.0 0.11 0.1093 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K20 mock treatment 1297404.0 180000.0 0.38 0.3824 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K21 mock treatment 1053733.0 -63300.0 -0.13 -0.1342 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K22 mock treatment 1042508.0 -74500.0 -0.16 -0.158 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K23 mock treatment 971075.0 -146000.0 -0.31 -0.3094 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base K24 mock treatment 758818.0 -358000.0 -0.76 -0.7594 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L01 mock treatment 628238.0 -489000.0 -1.04 -1.0362 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L02 mock treatment 882151.0 -235000.0 -0.5 -0.498 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L03 mock treatment 1034346.0 -82700.0 -0.18 -0.1753 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L04 mock treatment 924489.0 -193000.0 -0.41 -0.4082 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L05 mock treatment 1182296.0 65300.0 0.14 0.1383 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L06 mock treatment 1231454.0 114000.0 0.24 0.2426 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L07 mock treatment 1219233.0 102000.0 0.22 0.2166 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L08 mock treatment 1305186.0 188000.0 0.4 0.3989 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L09 mock treatment 1163229.0 46200.0 0.1 0.0979 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L10 mock treatment 1391945.0 275000.0 0.58 0.5828 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L11 mock treatment 1496685.0 380000.0 0.8 0.8048 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L12 mock treatment 1750639.0 634000.0 1.34 1.3432 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L13 mock treatment 1579126.0 462000.0 0.98 0.9796 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L14 mock treatment 1674975.0 558000.0 1.18 1.1828 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L15 mock treatment 1493795.0 377000.0 0.8 0.7987 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L16 mock treatment 1501231.0 384000.0 0.81 0.8145 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L17 mock treatment 1342617.0 226000.0 0.48 0.4782 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L18 mock treatment 1378794.0 262000.0 0.55 0.5549 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L19 mock treatment 1376914.0 260000.0 0.55 0.5509 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L20 mock treatment 1193020.0 76000.0 0.16 0.1611 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L21 mock treatment 1256833.0 140000.0 0.3 0.2964 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L22 mock treatment 1073926.0 -43100.0 -0.09 -0.0914 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L23 mock treatment 1119505.0 2470.0 0.01 0.0052 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base L24 mock treatment 829766.0 -287000.0 -0.61 -0.609 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M01 mock treatment 614268.0 -503000.0 -1.07 -1.0659 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M02 mock treatment 934353.0 -183000.0 -0.39 -0.3873 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M03 mock treatment 1253926.0 137000.0 0.29 0.2902 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M04 mock treatment 1002861.0 -114000.0 -0.24 -0.2421 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M05 mock treatment 1115660.0 -1380.0 0.0 -0.0029 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M06 mock treatment 1035108.0 -81900.0 -0.17 -0.1737 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M07 mock treatment 1175141.0 58100.0 0.12 0.1232 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M08 mock treatment 1130212.0 13200.0 0.03 0.0279 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M09 mock treatment 1063769.0 -53300.0 -0.11 -0.1129 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M10 mock treatment 1212550.0 95500.0 0.2 0.2025 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M11 mock treatment 1229026.0 112000.0 0.24 0.2374 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M12 mock treatment 1189996.0 73000.0 0.15 0.1547 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M13 mock treatment 1017753.0 -99300.0 -0.21 -0.2105 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M14 mock treatment 1201562.0 84500.0 0.18 0.1792 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M15 mock treatment 1066844.0 -50200.0 -0.11 -0.1064 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M16 mock treatment 1195430.0 78400.0 0.17 0.1662 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M17 mock treatment 1232491.0 115000.0 0.24 0.2448 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M18 mock treatment 1112602.0 -4440.0 -0.01 -0.0094 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M19 mock treatment 1396412.0 279000.0 0.59 0.5923 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M20 mock treatment 1185623.0 68600.0 0.15 0.1454 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M21 mock treatment 1316776.0 200000.0 0.42 0.4234 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M22 mock treatment 1162257.0 45200.0 0.1 0.0959 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M23 mock treatment 1117758.0 719.0 0.0 0.0015 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base M24 mock treatment 851091.0 -266000.0 -0.56 -0.5638 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N01 mock treatment 1003117.0 -114000.0 -0.24 -0.2415 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N02 mock treatment 1299136.0 182000.0 0.39 0.386 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N03 mock treatment 1143124.0 26100.0 0.06 0.0553 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N04 mock treatment 1119890.0 2850.0 0.01 0.006 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N05 mock treatment 1085751.0 -31300.0 -0.07 -0.0663 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N06 mock treatment 1155028.0 38000.0 0.08 0.0805 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N07 mock treatment 1140287.0 23200.0 0.05 0.0493 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N08 mock treatment 1222049.0 105000.0 0.22 0.2226 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N09 mock treatment 1207063.0 90000.0 0.19 0.1908 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N10 mock treatment 1018498.0 -98500.0 -0.21 -0.2089 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N11 mock treatment 1316447.0 199000.0 0.42 0.4227 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N12 mock treatment 1554908.0 438000.0 0.93 0.9283 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N13 mock treatment 1224443.0 107000.0 0.23 0.2277 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N14 mock treatment 1149116.0 32100.0 0.07 0.068 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N15 mock treatment 1357238.0 240000.0 0.51 0.5092 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N16 mock treatment 1212061.0 95000.0 0.2 0.2014 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N17 mock treatment 1111931.0 -5110.0 -0.01 -0.0108 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N18 mock treatment 1174237.0 57200.0 0.12 0.1213 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N19 mock treatment 1311157.0 194000.0 0.41 0.4115 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N20 mock treatment 1408910.0 292000.0 0.62 0.6188 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N21 mock treatment 1236903.0 120000.0 0.25 0.2541 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N22 mock treatment 1135713.0 18700.0 0.04 0.0396 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N23 mock treatment 1096864.0 -20200.0 -0.04 -0.0428 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base N24 mock treatment 846931.0 -270000.0 -0.57 -0.5726 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O01 mock treatment 658028.0 -459000.0 -0.97 -0.9731 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O02 mock treatment 1343271.0 226000.0 0.48 0.4796 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O03 mock treatment 1625041.0 508000.0 1.08 1.0769 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O04 mock treatment 1113074.0 -3970.0 -0.01 -0.0084 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O05 mock treatment 1048200.0 -68800.0 -0.15 -0.1459 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O06 mock treatment 1075958.0 -41100.0 -0.09 -0.0871 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O07 mock treatment 1164729.0 47700.0 0.1 0.1011 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O08 mock treatment 1030991.0 -86000.0 -0.18 -0.1824 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O09 mock treatment 1129385.0 12300.0 0.03 0.0262 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O10 mock treatment 1180846.0 63800.0 0.14 0.1353 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O11 mock treatment 1140301.0 23300.0 0.05 0.0493 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O12 mock treatment 1189024.0 72000.0 0.15 0.1526 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O13 mock treatment 1161180.0 44100.0 0.09 0.0936 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O14 mock treatment 1328397.0 211000.0 0.45 0.4481 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O15 mock treatment 1183714.0 66700.0 0.14 0.1413 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O16 mock treatment 1147535.0 30500.0 0.06 0.0646 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O17 mock treatment 1189476.0 72400.0 0.15 0.1536 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O18 mock treatment 1173763.0 56700.0 0.12 0.1203 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O19 mock treatment 1311017.0 194000.0 0.41 0.4112 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O20 mock treatment 1115219.0 -1820.0 0.0 -0.0039 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O21 mock treatment 1298786.0 182000.0 0.39 0.3853 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O22 mock treatment 1298406.0 181000.0 0.38 0.3845 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O23 mock treatment 1118929.0 1890.0 0.0 0.004 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base O24 mock treatment 749528.0 -368000.0 -0.78 -0.7791 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P01 mock treatment 465604.0 -651000.0 -1.38 -1.381 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P02 mock treatment 1072461.0 -44600.0 -0.09 -0.0945 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P03 mock treatment 1154808.0 37800.0 0.08 0.0801 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P04 mock treatment 1084333.0 -32700.0 -0.07 -0.0693 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P05 mock treatment 1271513.0 154000.0 0.33 0.3275 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P06 mock treatment 1275529.0 158000.0 0.34 0.336 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P07 mock treatment 1186811.0 69800.0 0.15 0.1479 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P08 mock treatment 1143417.0 26400.0 0.06 0.0559 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P09 mock treatment 1032194.0 -84800.0 -0.18 -0.1799 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P10 mock treatment 1103544.0 -13500.0 -0.03 -0.0286 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P11 mock treatment 1049331.0 -67700.0 -0.14 -0.1435 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P12 mock treatment 1020582.0 -96500.0 -0.2 -0.2045 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P13 mock treatment 955708.0 -161000.0 -0.34 -0.342 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P14 mock treatment 1111643.0 -5400.0 -0.01 -0.0114 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P15 mock treatment 1057440.0 -59600.0 -0.13 -0.1263 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P16 mock treatment 1122877.0 5840.0 0.01 0.0124 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P17 mock treatment 1265076.0 148000.0 0.31 0.3138 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P18 mock treatment 1179647.0 62600.0 0.13 0.1327 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P19 mock treatment 1530676.0 414000.0 0.88 0.8769 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P20 mock treatment 1476335.0 359000.0 0.76 0.7617 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P21 mock treatment 1076882.0 -40200.0 -0.09 -0.0851 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P22 mock treatment 1174393.0 57400.0 0.12 0.1216 1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P23 mock treatment 718328.0 -399000.0 -0.85 -0.8453 -1.0 1010.0014 DAPIStaining(1010.0014) PlasmodiumViabilityAssay 1010.0014.Base P24 mock treatment 528552.0 -588000.0 -1.25 -1.2476 -1.0