ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A01 compound treatment 52720.0 5920.0 0.34 47920.0 8030.0 0.61 0.672 0.9633 1042961 Maybridge4_000001 Clc1ccc(cc1)N2CCNCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A02 compound treatment 47760.0 956.0 0.06 47320.0 7430.0 0.56 0.4367 0.7731 3062731 Maybridge4_000002 CC(=O)NS(=O)(=O)c1ccc(/N=C/c2ccco2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A03 compound treatment 35000.0 -11800.0 -0.68 40040.0 146.0 0.01 -0.4757 -0.6956 3062732 Maybridge4_000003 FC(F)(F)Oc1ccc(NC(=O)Nc2ccc(cc2)C3=NCCO3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A04 compound treatment 50640.0 3840.0 0.22 36320.0 -3570.0 -0.27 -0.0341 -0.0974 1175682 Maybridge4_000004 COc1cccc2cc(C#N)c(=N)oc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A05 compound treatment 22960.0 -23800.0 -1.38 25080.0 -14800.0 -1.12 -1.7697 -0.9946 3062733 Maybridge4_000005 Cc1nc(ccc1C(=O)Sc2nnc(o2)c3ccc(nc3C)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A06 compound treatment 48920.0 2120.0 0.12 43040.0 3150.0 0.24 0.2551 0.9523 3062734 Maybridge4_000006 COc1cc(/N=C/c2cccs2)c(OC)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A07 compound treatment 50960.0 4160.0 0.24 43520.0 3630.0 0.27 0.3644 0.9979 3062735 Maybridge4_000007 OC1CCN(CC1)C(=O)Nc2ccc(OC(F)(F)F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A08 compound treatment 28600.0 -18200.0 -1.05 25400.0 -14500.0 -1.1 -1.5215 -0.9998 1676427 Maybridge4_000008 Cc1ccccc1NC(=S)Nc2cc(NS(=O)(=O)C)ccc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A09 compound treatment 43640.0 -3160.0 -0.18 32680.0 -7210.0 -0.55 -0.5157 -0.8954 3179439 Maybridge4_000009 Cc1nc(ccc1NC(=O)NCCNc2cccc(n2)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A10 compound treatment 45520.0 -1280.0 -0.07 42520.0 2630.0 0.2 0.088 0.4145 3062736 Maybridge4_000010 Cc1ccc(NC(=S)Nc2cccc(c2)C(F)(F)F)cc1NS(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A11 compound treatment 51200.0 4400.0 0.25 40000.0 106.0 0.01 0.1858 0.7291 3179440 Maybridge4_000011 CC(C)(C)NC(=O)N1CCC(CC1)Nc2nccc(n2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A12 compound treatment 41680.0 -5120.0 -0.3 32600.0 -7290.0 -0.55 -0.6003 -0.9577 3062737 Maybridge4_000012 Fc1cccc(/N=C/c2ccc3OCOc3c2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A13 compound treatment 49920.0 3120.0 0.18 39840.0 -53.8 0.0 0.1248 0.691 3179441 Maybridge4_000013 OC(=O)c1ccccc1C(=O)NC2CCN(CC2)c3nccc(n3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A14 compound treatment 2040.0 -44800.0 -2.59 1440.0 -38500.0 -2.91 -3.8921 -0.9983 3062738 Maybridge4_000014 CCOC(=O)CCN1C(=O)c2ccccc2C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A15 compound treatment 1400.0 -45400.0 -2.63 1160.0 -38700.0 -2.93 -3.9333 -0.9985 1678888 Maybridge4_000015 C(Cc1ccccc1)Nc2ncnc3scc(c4ccccc4)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A16 compound treatment 48640.0 1840.0 0.11 35160.0 -4730.0 -0.36 -0.1781 -0.4766 1222400 Maybridge4_000016 Oc1ccc(CCc2nnc(S)n2CCc3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A17 compound treatment 38000.0 -8800.0 -0.51 29320.0 -10600.0 -0.8 -0.9266 -0.9763 3179442 Maybridge4_000017 OC(=O)/C=C/C(=O)N1CCN(CC1)c2ncnc3scc(c4ccccc4)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A18 compound treatment 44720.0 -2080.0 -0.12 34000.0 -5890.0 -0.45 -0.4008 -0.8673 3179443 Maybridge4_000018 CN(C(=O)CSc1ccc(Cl)cc1)c2ccccc2C(=O)NC3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A19 compound treatment 46560.0 -244.0 -0.01 34120.0 -5770.0 -0.44 -0.319 -0.7296 1712315 Maybridge4_000019 COc1cccc(OC)c1C(=O)N2CCN(CC2)c3ncnc4scc(c5ccccc5)c34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A20 compound treatment 18920.0 -27900.0 -1.62 13440.0 -26500.0 -2.0 -2.5583 -0.9943 3179444 Maybridge4_000020 CC(C)(C)NC(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A21 compound treatment 45640.0 -1160.0 -0.07 40720.0 826.0 0.06 -0.0035 -0.0375 3062739 Maybridge4_000021 NC(=O)C1CCN(CC1)c2nccc(n2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A22 compound treatment 5240.0 -41600.0 -2.41 4560.0 -35300.0 -2.67 -3.594 -0.9986 1149418 Maybridge4_000022 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Oc2c(C)cccc2OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A23 mock treatment 50280.0 3480.0 0.2 41760.0 1870.0 0.14 0.2423 0.9849 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 A24 mock treatment 55480.0 8680.0 0.5 57200.0 17300.0 1.31 1.2817 0.9135 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B01 compound treatment 45760.0 -1040.0 -0.06 54000.0 14100.0 1.07 0.7123 0.666 3062740 Maybridge4_000023 CCSC1=NCN(Cc2cccs2)CN1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B02 compound treatment 42560.0 -4240.0 -0.25 42080.0 2190.0 0.17 -0.0568 -0.1918 3179445 Maybridge4_000024 Cc1ccc(CNC(=O)c2cccnc2Sc3cccc(c3)C(F)(F)F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B03 compound treatment 27400.0 -19400.0 -1.12 26080.0 -13800.0 -1.05 -1.5343 -0.9993 3062741 Maybridge4_000025 CN(/N=C/c1cc(Cl)cc(Cl)c1O)C(=S)NC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B04 compound treatment 38760.0 -8040.0 -0.47 33680.0 -6210.0 -0.47 -0.6621 -1.0 3179446 Maybridge4_000026 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccccc3NC(=O)/C=C\C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B05 compound treatment 40160.0 -6640.0 -0.38 31200.0 -8690.0 -0.66 -0.7375 -0.9674 3062742 Maybridge4_000027 Cc1c(C)c(C)c(CS(=O)(=O)CC(=O)Nc2ccc(F)c(Cl)c2)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B06 compound treatment 52800.0 6000.0 0.35 41280.0 1390.0 0.1 0.3199 0.8814 1435448 Maybridge4_000028 Cc1onc(c1NC(=O)Oc2ccc(CC#N)cc2)c3c(Cl)cccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B07 compound treatment 47520.0 716.0 0.04 39440.0 -454.0 -0.03 0.0051 0.0939 1192420 Maybridge4_000029 S=C(NCCc1ccccn1)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B08 compound treatment 43520.0 -3280.0 -0.19 35200.0 -4690.0 -0.36 -0.3858 -0.9572 1239033 Maybridge4_000030 CSc1nnc(SC)n1CCNC(=O)Nc2cccc(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B09 compound treatment 34120.0 -12700.0 -0.73 38160.0 -1730.0 -0.13 -0.6124 -0.8204 3179447 Maybridge4_000031 Fc1c(Br)cc(Br)c2nc(oc(=O)c12)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B10 compound treatment 1720.0 -45100.0 -2.61 1720.0 -38200.0 -2.89 -3.8902 -0.9987 3062743 Maybridge4_000032 Fc1ccc(Oc2ccc(NC(=O)/C=C/c3ccccc3)cn2)c(F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B11 compound treatment 25040.0 -21800.0 -1.26 24120.0 -15800.0 -1.19 -1.7359 -0.9996 3179448 Maybridge4_000033 FC(F)(F)c1ccc2[nH]c(SCc3ccc(Br)cc3)nc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B12 compound treatment 41800.0 -5000.0 -0.29 40160.0 266.0 0.02 -0.1907 -0.6564 1161087 Maybridge4_000034 Fc1ccc(cc1)n2nc3NCCCn3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B13 compound treatment 29080.0 -17700.0 -1.03 26960.0 -12900.0 -0.98 -1.4184 -0.9997 3062744 Maybridge4_000035 FC(F)(F)c1cccc(c1)C(=O)On2c(nc3ccccc3c2=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B14 compound treatment 40240.0 -6560.0 -0.38 33320.0 -6570.0 -0.5 -0.6208 -0.9912 1279124 Maybridge4_000036 CCCCn1c(CSc2ccccn2)cn(c3nnc(s3)C(C)(C)C)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B15 compound treatment 35720.0 -11100.0 -0.64 30720.0 -9170.0 -0.69 -0.9451 -0.9992 1108923 Maybridge4_000037 CSC1=NC=C(C#N)C2=NC(NN21)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B16 compound treatment 15240.0 -31600.0 -1.83 8400.0 -31500.0 -2.38 -2.9788 -0.9914 1163777 Maybridge4_000038 CC(C)(C)c1cc(cc(c1)C(=O)Oc2cncc(Cl)c2)C(=O)Oc3cncc(Cl)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B17 compound treatment 51400.0 4600.0 0.27 47440.0 7550.0 0.57 0.5922 0.9397 1150645 Maybridge4_000039 Cc1cc(NS(=O)(=O)c2ccc(F)c(Cl)c2)no1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B18 compound treatment 49000.0 2200.0 0.13 42080.0 2190.0 0.17 0.207 0.9916 3179449 Maybridge4_000040 CSc1ncccc1C2=N/C(=C\N(C)C)/C(=O)O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B19 compound treatment 44560.0 -2240.0 -0.13 37840.0 -2050.0 -0.16 -0.2018 -0.996 3062745 Maybridge4_000041 CN(C)/C=N/c1nnc(SCC(=O)c2ccc(F)cc2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B20 compound treatment 60240.0 13400.0 0.78 52360.0 12500.0 0.94 1.2177 0.9954 3179558 Maybridge4_000042 COC(=O)/C(=C/1\NC(=NC(=C1C#N)SC)C)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B21 compound treatment 3880.0 -42900.0 -2.49 2800.0 -37100.0 -2.81 -3.7439 -0.9982 3179559 Maybridge4_000043 CN(C)/C=N/c1nnc(Sc2cc(C)nc3ccccc23)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B22 compound treatment 5920.0 -40900.0 -2.37 4800.0 -35100.0 -2.66 -3.5533 -0.9984 3062746 Maybridge4_000044 CCOC(=O)c1c(C)c(C#N)c(/N=C/N(C)C)n1c2ccc(Cl)cc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B23 mock treatment 58680.0 11900.0 0.69 43480.0 3590.0 0.27 0.6785 0.9173 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 B24 mock treatment 49360.0 2560.0 0.15 48960.0 9070.0 0.69 0.59 0.8404 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C01 compound treatment 56760.0 9960.0 0.58 50840.0 10900.0 0.83 0.9938 0.9843 1040601 Maybridge4_000045 COc1cccc(c1)N2CCNCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C02 compound treatment 38720.0 -8080.0 -0.47 33800.0 -6090.0 -0.46 -0.6573 -1.0 3062747 Maybridge4_000046 COc1cc(/C=N/N)cc(OC)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C03 compound treatment 55840.0 9040.0 0.52 47400.0 7510.0 0.57 0.772 0.9992 3179560 Maybridge4_000047 FC(F)(F)c1cccnc1N2CCNC2=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C04 compound treatment 20440.0 -26400.0 -1.53 16080.0 -23800.0 -1.8 -2.3547 -0.9966 1723231 Maybridge4_000048 Clc1c(sc2ccccc12)C(=O)N(Cc3ccccc3)C(C#N)c4ccc5OCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C05 compound treatment 2280.0 -44500.0 -2.58 1720.0 -38200.0 -2.89 -3.8673 -0.9984 3062748 Maybridge4_000049 Cc1ccc(NC(=S)N2CCCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C06 compound treatment 48080.0 1280.0 0.07 40120.0 226.0 0.02 0.0644 0.8484 1322626 Maybridge4_000050 Fc1ccc(cc1)N(Cc2ccc3OCOc3c2)S(=O)(=O)c4ccc(F)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C07 compound treatment 43720.0 -3080.0 -0.18 34600.0 -5290.0 -0.4 -0.4097 -0.9338 1288233 Maybridge4_000051 CCOC(=O)c1cc(C(=O)OC)c(C)nc1N2CCCN(Cc3ccc(F)cc3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C08 compound treatment 50040.0 3240.0 0.19 43400.0 3510.0 0.27 0.3203 0.9855 3179561 Maybridge4_000052 CCOC(=O)/C(=C(/C)\N)/C1CC(=O)N(C1=O)c2ccc(cc2)C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C09 compound treatment 8240.0 -38600.0 -2.23 9800.0 -30100.0 -2.28 -3.1906 -1.0 1354107 Maybridge4_000053 OC(COc1ccc(Br)cc1)CN2CCCN(CC2)c3nc4ccc(Cl)cc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C10 compound treatment 30800.0 -16000.0 -0.93 28320.0 -11600.0 -0.88 -1.2751 -0.9996 1692586 Maybridge4_000054 Cc1ccc(cc1)S(=O)(=O)N(c2nc3ccccc3s2)c4cccc(Cl)c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C11 compound treatment 49240.0 2440.0 0.14 37480.0 -2410.0 -0.18 -0.0294 -0.1273 1369581 Maybridge4_000055 CC(C)(C)OC(=O)N1CCCN(CC1)C(=O)Nc2ccc(F)cc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C12 compound treatment 41760.0 -5040.0 -0.29 35120.0 -4770.0 -0.36 -0.4621 -0.9945 1212228 Maybridge4_000056 Cc1ccc(c(NC(=O)C(C2CCCC2)c3ccccc3)c1)n4cccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C13 compound treatment 50240.0 3440.0 0.2 43560.0 3670.0 0.28 0.337 0.9867 3179562 Maybridge4_000057 Cc1nc(ccc1C(=O)NCC2CC2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C14 compound treatment 6640.0 -40200.0 -2.33 7520.0 -32400.0 -2.45 -3.3782 -0.9997 1629863 Maybridge4_000058 Oc1c(Cl)cc(Cl)cc1C2Nc3cccc4cccc(N2)c34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C15 compound treatment 41240.0 -5560.0 -0.32 31600.0 -8290.0 -0.63 -0.6719 -0.952 3062749 Maybridge4_000059 CCCNC(=O)NC1CCN(CC1)c2ncc(cc2Cl)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C16 compound treatment 32680.0 -14100.0 -0.82 27160.0 -12700.0 -0.96 -1.2602 -0.9967 1569566 Maybridge4_000060 CC(c1ccccc1)n2c(S)nnc2CCc3ccc(O)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C17 compound treatment 50240.0 3440.0 0.2 43000.0 3110.0 0.24 0.307 0.9966 1204274 Maybridge4_000061 Fc1cccc(Cl)c1CN2CCN(CCCN3C(=O)c4ccccc4C3=O)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C18 compound treatment 29080.0 -17700.0 -1.03 32600.0 -7290.0 -0.55 -1.1165 -0.9576 1455358 Maybridge4_000062 O=C(Nc1nccc2ccccc12)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C19 compound treatment 24240.0 -22600.0 -1.31 23480.0 -16400.0 -1.24 -1.8029 -0.9997 3179563 Maybridge4_000063 COc1cccc(CC(=O)NC2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C20 compound treatment 45560.0 -1240.0 -0.07 42280.0 2390.0 0.18 0.0768 0.3948 3062750 Maybridge4_000064 CC(C)(C)NC(=S)Nc1ccccc1C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C21 compound treatment 43240.0 -3560.0 -0.21 33680.0 -6210.0 -0.47 -0.4786 -0.9317 1137780 Maybridge4_000065 CC(C)(C)OC(=O)N1CCN(CC1)C(=O)c2ccc(Oc3cccnc3)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C22 compound treatment 43080.0 -3720.0 -0.22 34360.0 -5530.0 -0.42 -0.4487 -0.9524 3179564 Maybridge4_000066 FC(F)(F)c1cc(NCC(=O)c2cc3cc(Cl)ccc3o2)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C23 mock treatment 50160.0 3360.0 0.19 46160.0 6270.0 0.47 0.4729 0.9225 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 C24 mock treatment 53120.0 6320.0 0.37 44440.0 4550.0 0.34 0.5021 0.9995 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D01 compound treatment 33560.0 -13200.0 -0.77 24640.0 -15300.0 -1.15 -1.359 -0.9803 3179565 Maybridge4_000067 Cc1nn(nc1C(=O)Oc2c(Cl)cccc2Cl)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D02 compound treatment 47640.0 836.0 0.05 39000.0 -894.0 -0.07 -0.0136 -0.1632 3062751 Maybridge4_000068 COc1cc(cc(Br)c1OC(=O)NC(=O)c2c(F)cccc2F)C3SCCS3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D03 compound treatment 23960.0 -22800.0 -1.32 19280.0 -20600.0 -1.56 -2.0392 -0.9966 1545199 Maybridge4_000069 CCOC(=O)c1cnc2cc(Cl)c(F)cc2c1N3CC(C)OC(C)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D04 compound treatment 43800.0 -3000.0 -0.17 40520.0 626.0 0.05 -0.0895 -0.4964 1652603 Maybridge4_000070 CC(C)(C)c1ccc(cc1)c2nnc(o2)c3ccccc3NC(=O)CCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D05 compound treatment 49400.0 2600.0 0.15 38480.0 -1410.0 -0.11 0.0307 0.1663 1338281 Maybridge4_000071 Clc1ccccc1C(=O)NC(=O)NC2CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D06 compound treatment 51520.0 4720.0 0.27 43560.0 3670.0 0.28 0.3894 1.0 1457562 Maybridge4_000072 OC(=O)C(CCC(=O)Nc1ccc2OCOCc2c1)N3C(=O)c4ccccc4C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D07 compound treatment 47240.0 436.0 0.03 41160.0 1270.0 0.1 0.0856 0.864 3062752 Maybridge4_000073 CC1CN(CC(C)O1)C2=NCCN2S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D08 compound treatment 47440.0 636.0 0.04 40920.0 1030.0 0.08 0.081 0.942 3179566 Maybridge4_000074 Cc1nn(nc1C(=O)c2c(O)n(nc2C(C)(C)C)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D09 compound treatment 26160.0 -20600.0 -1.2 26080.0 -13800.0 -1.05 -1.5851 -0.9978 3062753 Maybridge4_000075 Cc1cc(Br)c(c(Br)c1Cl)n2cccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D10 compound treatment 46240.0 -564.0 -0.03 39960.0 66.3 0.01 -0.0195 -0.5916 3179567 Maybridge4_000076 Fc1ccc(Oc2ncccc2NC(=O)/C=C/c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D11 compound treatment 39040.0 -7760.0 -0.45 32360.0 -7530.0 -0.57 -0.7213 -0.9931 3062754 Maybridge4_000077 CC(C)(C)c1cs/c(=N/c2ccccn2)/n1c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D12 compound treatment 45800.0 -1000.0 -0.06 38920.0 -974.0 -0.07 -0.0932 -0.9931 1415138 Maybridge4_000078 CN1C(C(=O)N(C1=O)c2nnc(s2)C(C)(C)C)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D13 compound treatment 30480.0 -16300.0 -0.95 28680.0 -11200.0 -0.85 -1.269 -0.9985 3063175 Maybridge4_000079 CC(C)(C)c1csc(Cc2ccccc2Cl)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D14 compound treatment 39440.0 -7360.0 -0.43 33920.0 -5970.0 -0.45 -0.6214 -0.9996 3179568 Maybridge4_000080 Fc1ccc(NC(=O)CSc2nnc(NC(=O)c3ccc(Cl)c(Cl)c3)s2)c(F)c1F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D15 compound treatment 47960.0 1160.0 0.07 40680.0 786.0 0.06 0.0895 0.9983 1691601 Maybridge4_000081 CS(=O)(=O)Nc1ccc2oc3ncccc3c(=O)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D16 compound treatment 42240.0 -4560.0 -0.26 35840.0 -4050.0 -0.31 -0.4039 -0.9973 1489888 Maybridge4_000082 CC(C)(C)c1cc(cc(c1)C(=O)NCc2cccs2)C(=O)NCc3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D17 compound treatment 47920.0 1120.0 0.06 43200.0 3310.0 0.25 0.2227 0.8615 3063176 Maybridge4_000083 Clc1ccc(cc1Cl)C(=O)c2nn3c(nc(=O)c4ccccc43)s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D18 compound treatment 37520.0 -9280.0 -0.54 33600.0 -6290.0 -0.48 -0.7172 -0.9982 3179569 Maybridge4_000084 CN(C)/C=C/1\N=C(OC1=O)c2cccnc2Oc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D19 compound treatment 45280.0 -1520.0 -0.09 40360.0 466.0 0.04 -0.0375 -0.3941 1342823 Maybridge4_000085 Fc1ccc(c(F)c1)S(=O)(=O)Nc2ccccc2C(=O)NCC3CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D20 compound treatment 38200.0 -8600.0 -0.5 36000.0 -3890.0 -0.29 -0.5609 -0.9686 3063177 Maybridge4_000086 CC(C)(C(=O)Nc1cccc(Cl)c1)S(=O)(=O)c2ccc(cn2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D21 compound treatment 42960.0 -3840.0 -0.22 39920.0 26.3 0.0 -0.1561 -0.7008 3063178 Maybridge4_000087 CC1=NN(C(=O)CC1)c2cc(Cl)cc(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D22 compound treatment 19200.0 -27600.0 -1.6 14600.0 -25300.0 -1.91 -2.4847 -0.996 1609394 Maybridge4_000088 CCOC(=O)c1c(C)c(C#N)c(N(C(=O)C)C(=O)C)n1c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D23 mock treatment 51160.0 4360.0 0.25 38920.0 -974.0 -0.07 0.1263 0.4805 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 D24 mock treatment 52760.0 5960.0 0.35 42640.0 2750.0 0.21 0.391 0.9706 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E01 compound treatment 51200.0 4400.0 0.25 46360.0 6470.0 0.49 0.5262 0.9537 1042964 Maybridge4_000089 Cc1cccc(c1)N2CCNCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E02 compound treatment 47800.0 996.0 0.06 40520.0 626.0 0.05 0.0743 0.9952 1679137 Maybridge4_000090 NNC(=O)C1CCCNC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E03 compound treatment 34960.0 -11800.0 -0.69 31800.0 -8090.0 -0.61 -0.9184 -0.9984 1296373 Maybridge4_000091 CC(C)(C)OC(=O)N1CCCN(CC1)S(=O)(=O)c2cc(Cl)ccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E04 compound treatment 45600.0 -1200.0 -0.07 36680.0 -3210.0 -0.24 -0.2213 -0.8746 1584716 Maybridge4_000092 COc1cc(cc(OC)c1OC)C(=O)NC(=S)NC(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E05 compound treatment 43680.0 -3120.0 -0.18 38480.0 -1410.0 -0.11 -0.2036 -0.9686 3063179 Maybridge4_000093 CSc1nnc(o1)c2ccc(nc2C)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E06 compound treatment 26360.0 -20400.0 -1.18 25480.0 -14400.0 -1.09 -1.609 -0.9992 3179570 Maybridge4_000094 Cc1onc(c1C(=O)NC(=S)Nc2ccc(Cl)cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E07 compound treatment 52680.0 5880.0 0.34 36760.0 -3130.0 -0.24 0.073 0.1759 1200576 Maybridge4_000095 CCOC(=O)c1cc(C(=O)OC)c(C)nc1SCC(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E08 compound treatment 39520.0 -7280.0 -0.42 32080.0 -7810.0 -0.59 -0.7166 -0.9863 1402318 Maybridge4_000096 CCOC(=O)C1=C(C)NC(=O)C1CC(=O)Nc2ccc(cc2)C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E09 compound treatment 38720.0 -8080.0 -0.47 36920.0 -2970.0 -0.23 -0.4903 -0.9436 1736057 Maybridge4_000097 CCOC(=O)c1cc(C#N)c(C)nc1N2CCN(CC2)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E10 compound treatment 45440.0 -1360.0 -0.08 38800.0 -1090.0 -0.08 -0.1144 -0.9997 1619754 Maybridge4_000098 CC(=O)Nc1ccc(C)c(NC(=S)Nc2ccc(Cl)c(Cl)c2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E11 compound treatment 43720.0 -3080.0 -0.18 38520.0 -1370.0 -0.1 -0.1999 -0.9668 1175297 Maybridge4_000099 O=C1CC2(CCCC2)C(=O)N1CCc3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E12 compound treatment 39280.0 -7520.0 -0.44 33720.0 -6170.0 -0.47 -0.6387 -0.9994 3179665 Maybridge4_000100 COc1cc(NC(=O)C(C2CCCC2)c3ccccc3)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E13 compound treatment 37200.0 -9600.0 -0.56 34800.0 -5090.0 -0.39 -0.6661 -0.9839 1528875 Maybridge4_000101 COc1ccccc1C2CCN(CC2)S(=O)(=O)c3ccc(s3)c4csc(C)n4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E14 compound treatment 37920.0 -8880.0 -0.51 29280.0 -10600.0 -0.8 -0.932 -0.9768 1511104 Maybridge4_000102 CN(C)c1ccc(cc1)C2N(Cc3ccccc3)CCC4CCCCN24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E15 compound treatment 41400.0 -5400.0 -0.31 32560.0 -7330.0 -0.56 -0.6139 -0.9633 3063180 Maybridge4_000103 FC(F)(F)Oc1ccc(NC(=O)NC2CCN(CC2)c3nccc(n3)C(F)(F)F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E16 compound treatment 30440.0 -16400.0 -0.95 29120.0 -10800.0 -0.82 -1.247 -0.9972 3179666 Maybridge4_000104 C/C(=N\C(=O)NN)/c1cnn(c1C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E17 compound treatment 4360.0 -42400.0 -2.46 3520.0 -36400.0 -2.75 -3.6857 -0.9984 3179667 Maybridge4_000105 C(CNc1ncnc2scc(c3ccccc3)c12)Cn4ccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E18 compound treatment 23000.0 -23800.0 -1.38 21560.0 -18300.0 -1.39 -1.9565 -1.0 1369305 Maybridge4_000106 CCN1CCCC1CN2CNC(=S)NC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E19 compound treatment 47720.0 916.0 0.05 39360.0 -534.0 -0.04 0.009 0.1344 3179668 Maybridge4_000107 FC(F)(F)c1ccnc(n1)N2CCN(CCCN3C(=O)c4ccccc4C3=O)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E20 compound treatment 35360.0 -11400.0 -0.66 33040.0 -6850.0 -0.52 -0.8357 -0.9926 3063181 Maybridge4_000108 CSc1cccc(NC(=S)NC(C)(C)C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E21 compound treatment 2640.0 -44200.0 -2.56 2320.0 -37600.0 -2.84 -3.8204 -0.9986 1338166 Maybridge4_000109 Cc1cnc(N2CCN(CC2)NC(=S)Nc3cccnc3)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E22 compound treatment 47000.0 196.0 0.01 36880.0 -3010.0 -0.23 -0.1533 -0.671 1138152 Maybridge4_000110 COc1ccc(NC(=S)NC(C)(C)C)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E23 mock treatment 51920.0 5120.0 0.3 40880.0 986.0 0.07 0.2624 0.8584 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 E24 mock treatment 50320.0 3520.0 0.2 38200.0 -1690.0 -0.13 0.0534 0.2218 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F01 compound treatment 51800.0 5000.0 0.29 41400.0 1510.0 0.11 0.2853 0.917 1442676 Maybridge4_000111 Fc1cccc(Cl)c1C(=O)NC(=O)N2CCSC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F02 compound treatment 38160.0 -8640.0 -0.5 28120.0 -11800.0 -0.89 -0.9843 -0.9628 3179669 Maybridge4_000112 CN(C)/C(=N/c1nnc(Sc2nc3cc(Cl)ccc3s2)s1)/C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F03 compound treatment 34520.0 -12300.0 -0.71 23280.0 -16600.0 -1.26 -1.3925 -0.9637 3179670 Maybridge4_000113 Fc1ccc(NC(=O)NCSCc2cccc(c2)C(F)(F)F)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F04 compound treatment 39880.0 -6920.0 -0.4 33000.0 -6890.0 -0.52 -0.6526 -0.9916 1189445 Maybridge4_000114 COc1cccc(c1)c2nnc(o2)c3ccccc3NS(=O)(=O)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F05 compound treatment 44520.0 -2280.0 -0.13 34960.0 -4930.0 -0.37 -0.3576 -0.9027 3179671 Maybridge4_000115 FC(F)(F)c1cccc(c1)C(=O)NC2CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F06 compound treatment 38680.0 -8120.0 -0.47 30360.0 -9530.0 -0.72 -0.8431 -0.9786 1529642 Maybridge4_000116 Cc1cc2ncc(nc2cc1C)c3ccn(c3)S(=O)(=O)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F07 compound treatment 46400.0 -404.0 -0.02 40960.0 1070.0 0.08 0.0405 0.4823 1440337 Maybridge4_000117 Clc1cccc(Cl)c1C(=O)NC2CCS(=O)(=O)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F08 compound treatment 45000.0 -1800.0 -0.1 32480.0 -7410.0 -0.56 -0.4707 -0.8246 1688196 Maybridge4_000118 COc1ccc(Cl)c(OC)c1C(=O)NC(=O)Nc2c(C)cccc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F09 compound treatment 31880.0 -14900.0 -0.86 27000.0 -12900.0 -0.98 -1.3015 -0.9982 3063182 Maybridge4_000119 COC(=O)/C=C/1\S/C(=N\c2ccc(C)c(C)c2)/N(C1=O)c3ccc(C)c(C)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F10 compound treatment 46360.0 -444.0 -0.03 35720.0 -4170.0 -0.32 -0.2416 -0.7621 3179672 Maybridge4_000120 NNC(=O)CS(=O)(=O)c1ccc(cn1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F11 compound treatment 30480.0 -16300.0 -0.95 22960.0 -16900.0 -1.28 -1.5751 -0.9888 3179673 Maybridge4_000121 Cc1ncc(CSc2nc3cc(ccc3[nH]2)C(F)(F)F)c(CO)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F12 compound treatment 16520.0 -30300.0 -1.75 14160.0 -25700.0 -1.95 -2.618 -0.9986 1621608 Maybridge4_000122 Cc1cc(cc(C)c1O)c2nn(C)c(=O)c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F13 compound treatment 40520.0 -6280.0 -0.36 32320.0 -7570.0 -0.57 -0.6628 -0.976 1331054 Maybridge4_000123 CC(C)c1cccc(C(C)C)c1OC(=O)NC(=O)c2c(F)cccc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F14 compound treatment 1720.0 -45100.0 -2.61 1400.0 -38500.0 -2.91 -3.9073 -0.9985 3063183 Maybridge4_000124 FC(F)(F)c1nnc(NC(=O)Nc2ccccc2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F15 compound treatment 44920.0 -1880.0 -0.11 35720.0 -4170.0 -0.32 -0.3006 -0.8992 3179674 Maybridge4_000125 COc1cc2c(=O)oc(nc2c(OC)c1OC)c3c(C)onc3c4c(F)cccc4Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F16 compound treatment 42960.0 -3840.0 -0.22 26080.0 -13800.0 -1.05 -0.8968 -0.8389 3063184 Maybridge4_000126 Brc1ccc(s1)c2cnc3ccccc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F17 compound treatment 27240.0 -19600.0 -1.13 24120.0 -15800.0 -1.19 -1.6458 -0.9997 1216365 Maybridge4_000127 Clc1ccc(Oc2nc(Oc3ccc(Cl)cc3)nc(n2)N4CCSCC4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F18 compound treatment 48000.0 1200.0 0.07 40000.0 106.0 0.01 0.0547 0.7839 1464435 Maybridge4_000128 CC(C)(C)c1ccc(Oc2ncccc2C(=O)O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F19 compound treatment 28400.0 -18400.0 -1.07 22160.0 -17700.0 -1.34 -1.7031 -0.9935 1281583 Maybridge4_000129 Cc1nn(nc1C(=O)NC(=O)N2CCSCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F20 compound treatment 42480.0 -4320.0 -0.25 37440.0 -2450.0 -0.19 -0.3085 -0.9892 3063185 Maybridge4_000130 CC(C)(C(=O)Oc1ccccc1)S(=O)(=O)c2ccc(cn2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F21 compound treatment 41640.0 -5160.0 -0.3 37080.0 -2810.0 -0.21 -0.3622 -0.9861 3179675 Maybridge4_000131 CC(C)(C)SCCNc1nc(Sc2ccc(Cl)cc2)nc(n1)N3CCSCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F22 compound treatment 40880.0 -5920.0 -0.34 34280.0 -5610.0 -0.42 -0.5432 -0.9944 3063186 Maybridge4_000132 CSc1nn(C)c2cnn(C)c(=O)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F23 mock treatment 46960.0 156.0 0.01 43400.0 3510.0 0.27 0.1941 0.7308 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 F24 mock treatment 51240.0 4440.0 0.26 41080.0 1190.0 0.09 0.2452 0.9008 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G01 compound treatment 42760.0 -4040.0 -0.23 42880.0 2990.0 0.23 -0.0058 -0.0179 3063187 Maybridge4_000133 Cc1ccccc1N2CCNCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G02 compound treatment 46120.0 -684.0 -0.04 36560.0 -3330.0 -0.25 -0.2064 -0.8082 3179676 Maybridge4_000134 c1ccc(nc1)c2nnc([nH]2)c3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G03 compound treatment 24640.0 -22200.0 -1.28 24040.0 -15900.0 -1.2 -1.7566 -0.9994 1229940 Maybridge4_000135 OC(CNCc1ccc(Cl)cc1Cl)Cn2c(cc3ccccc23)c4ccc(F)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G04 compound treatment 38160.0 -8640.0 -0.5 28240.0 -11700.0 -0.88 -0.9779 -0.964 3063224 Maybridge4_000136 NC(=O)NC(=S)NC(=O)c1ccccc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G05 compound treatment 35200.0 -11600.0 -0.67 30920.0 -8970.0 -0.68 -0.9557 -1.0 3063225 Maybridge4_000137 FC(F)(F)c1cccc(NC(=S)NCCNc2nccc(n2)C(F)(F)F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G06 compound treatment 43080.0 -3720.0 -0.22 36800.0 -3090.0 -0.23 -0.3181 -0.9992 1407734 Maybridge4_000138 Cc1cccc(C)c1NC(=S)N2CCCc3cccc(C)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G07 compound treatment 45680.0 -1120.0 -0.07 38680.0 -1210.0 -0.09 -0.111 -0.9858 3063226 Maybridge4_000139 Cc1nc(ccc1C(=O)O)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G08 compound treatment 43120.0 -3680.0 -0.21 34880.0 -5010.0 -0.38 -0.4193 -0.9629 3063227 Maybridge4_000140 CC(C)N(Cc1ccc(cc1)N(C)C)S(=O)(=O)c2cccc(c2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G09 compound treatment 38640.0 -8160.0 -0.47 34360.0 -5530.0 -0.42 -0.6306 -0.9982 1525364 Maybridge4_000141 COc1ccccc1NC(=O)N2CCCN(Cc3ccc(F)cc3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G10 compound treatment 37720.0 -9080.0 -0.53 29000.0 -10900.0 -0.82 -0.9552 -0.9765 3179677 Maybridge4_000142 Cc1cccc2c(=O)n(CCNCc3ccccc3)c(C)nc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G11 compound treatment 31560.0 -15200.0 -0.88 28480.0 -11400.0 -0.86 -1.2354 -0.9999 1397176 Maybridge4_000143 Cc1cc(c(C)cc1Cl)S(=O)(=O)N2CCCN(CC2)c3nc4ccc(Cl)cc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G12 compound treatment 44160.0 -2640.0 -0.15 32640.0 -7250.0 -0.55 -0.4966 -0.8711 1223333 Maybridge4_000144 COc1cc2CCN=C(c3c(C)onc3c4ccccc4)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G13 compound treatment 1880.0 -44900.0 -2.6 1960.0 -37900.0 -2.87 -3.8708 -0.9988 3179678 Maybridge4_000145 Clc1ccc(cc1)S(=O)(=O)NCCNc2ncnc3scc(c4ccccc4)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G14 compound treatment 40880.0 -5920.0 -0.34 28360.0 -11500.0 -0.87 -0.86 -0.9168 3063228 Maybridge4_000146 FC(F)(F)c1cc(NC(=O)CSC(=O)c2ccco2)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G15 compound treatment 11680.0 -35100.0 -2.03 10160.0 -29700.0 -2.25 -3.0304 -0.9987 1479980 Maybridge4_000147 COc1cccc(OC)c1C(=O)N2CCCN(CC2)c3nc4ccc(Cl)cc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G16 compound treatment 29360.0 -17400.0 -1.01 19000.0 -20900.0 -1.58 -1.833 -0.9766 3063229 Maybridge4_000148 FC(F)(F)c1cccc(c1)N2CCNC2=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G17 compound treatment 32640.0 -14200.0 -0.82 22360.0 -17500.0 -1.33 -1.5187 -0.9733 1615569 Maybridge4_000149 Ic1ccc(cc1)N2C(=O)CC3(CCCC3)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G18 compound treatment 42880.0 -3920.0 -0.23 33920.0 -5970.0 -0.45 -0.4805 -0.9494 3063230 Maybridge4_000150 FC(F)(F)c1cc(Br)ccc1/N=C/c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G19 compound treatment 32760.0 -14000.0 -0.81 28360.0 -11500.0 -0.87 -1.1927 -0.9994 3179679 Maybridge4_000151 Fc1cccc(Cl)c1CN2CCN(CCCNC(=O)c3cccc(c3)C(F)(F)F)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G20 compound treatment 35600.0 -11200.0 -0.65 33840.0 -6050.0 -0.46 -0.783 -0.9855 3063231 Maybridge4_000152 Cc1ccc(NC(=S)NC(C)(C)C)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G21 compound treatment 4120.0 -42700.0 -2.47 3840.0 -36100.0 -2.73 -3.6784 -0.9988 3179680 Maybridge4_000153 CSc1cccc(NC(=O)/C=C/c2ccc(cc2)C(C)C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G22 compound treatment 24920.0 -21900.0 -1.27 21240.0 -18700.0 -1.41 -1.895 -0.9986 3063232 Maybridge4_000154 S=C1NCN(Cc2cccs2)CN1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G23 mock treatment 43120.0 -3680.0 -0.21 34760.0 -5130.0 -0.39 -0.4257 -0.9602 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 G24 mock treatment 46520.0 -284.0 -0.02 43560.0 3670.0 0.28 0.1846 0.6641 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H01 compound treatment 50960.0 4160.0 0.24 36600.0 -3290.0 -0.25 -0.006 -0.0174 3179681 Maybridge4_000155 Cc1ccc(SCc2ccccc2c3nc4ccccc4[nH]3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H02 compound treatment 32480.0 -14300.0 -0.83 30560.0 -9330.0 -0.71 -1.0864 -0.9968 3063233 Maybridge4_000156 CN(C)/C=N/c1nnc(SCC(=O)Nc2cc(Cl)cc(Cl)c2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H03 compound treatment 44880.0 -1920.0 -0.11 41960.0 2070.0 0.16 0.0318 0.1655 3179769 Maybridge4_000157 CCC(C)n1c(=O)[nH][nH]c1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H04 compound treatment 47120.0 316.0 0.02 37600.0 -2290.0 -0.17 -0.1098 -0.629 1039773 Maybridge4_000158 Cc1ccc(=O)n(Cc2ccccc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H05 compound treatment 46400.0 -404.0 -0.02 35480.0 -4410.0 -0.33 -0.2528 -0.7548 3179770 Maybridge4_000159 Fc1cccc(CSC2=NCN(CN2)C3CC3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H06 compound treatment 34480.0 -12300.0 -0.71 22040.0 -17900.0 -1.35 -1.4605 -0.9555 3063234 Maybridge4_000160 FC(F)(F)c1cc(COc2ccc(CC#N)cc2)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H07 compound treatment 48080.0 1280.0 0.07 33240.0 -6650.0 -0.5 -0.3038 -0.5969 1661120 Maybridge4_000161 COc1ccc(OC)c(c1)S(=O)(=O)NC2CCS(=O)(=O)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H08 compound treatment 38400.0 -8400.0 -0.49 32360.0 -7530.0 -0.57 -0.7475 -0.9969 3063235 Maybridge4_000162 CN(C)/C=N/c1ccc(Oc2cncc(Cl)c2)nc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H09 compound treatment 27560.0 -19200.0 -1.11 24160.0 -15700.0 -1.19 -1.6305 -0.9995 3179771 Maybridge4_000163 Fc1ccc2sc(NC(=O)NC(=O)c3c(Cl)cccc3Cl)nc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H10 compound treatment 31680.0 -15100.0 -0.88 29680.0 -10200.0 -0.77 -1.1663 -0.9981 3063236 Maybridge4_000164 CC(=C)C(=O)Nc1ccc(Oc2ccccc2F)nc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H11 compound treatment 34680.0 -12100.0 -0.7 29600.0 -10300.0 -0.78 -1.0477 -0.9987 3179772 Maybridge4_000165 Cc1cc(ccc1Cl)C2(O)CSc3nc4cc(ccc4n32)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H12 compound treatment 1760.0 -45000.0 -2.61 1480.0 -38400.0 -2.91 -3.9014 -0.9985 1316383 Maybridge4_000166 Cc1ccc(cc1)C(=O)Oc2c(C)cc(cc2C)c3nn(C)c(=O)c4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H13 compound treatment 28960.0 -17800.0 -1.03 23680.0 -16200.0 -1.23 -1.5988 -0.9964 1008407 Maybridge4_000167 Clc1ccc(OCOc2ccc(Cl)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H14 compound treatment 29640.0 -17200.0 -0.99 24120.0 -15800.0 -1.19 -1.5474 -0.9959 3179773 Maybridge4_000168 CN(C)/C=C(\Sc1nnc(N)s1)/C(=O)Nc2ccc(F)c(F)c2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H15 compound treatment 39920.0 -6880.0 -0.4 31960.0 -7930.0 -0.6 -0.7067 -0.9802 3063237 Maybridge4_000169 O=c1ncn(Cc2cccs2)cc1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H16 compound treatment 44880.0 -1920.0 -0.11 35800.0 -4090.0 -0.31 -0.2979 -0.9047 1639465 Maybridge4_000170 COC(=O)CNC(=O)c1cccnc1Sc2cc(OC)ccc2OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H17 compound treatment 35920.0 -10900.0 -0.63 29440.0 -10500.0 -0.79 -1.0054 -0.9937 3063238 Maybridge4_000171 CCOC(=O)c1cc(CC)sc1NC(=S)Nc2ccccc2C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H18 compound treatment 24520.0 -22300.0 -1.29 24680.0 -15200.0 -1.15 -1.7272 -0.9984 1639248 Maybridge4_000172 CN(N1CC(C)(C)C1=O)c2cnn(c3ccc(C)cc3)c(=O)c2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H19 compound treatment 45800.0 -1000.0 -0.06 34360.0 -5530.0 -0.42 -0.3373 -0.7976 1494290 Maybridge4_000173 CC1CN(CC(C)O1)C(=O)NC(=O)c2nn(nc2C)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H20 compound treatment 52040.0 5240.0 0.3 40560.0 666.0 0.05 0.2502 0.8135 3179774 Maybridge4_000174 Cc1ccc(/C=C/c2onc3c(=O)[nH]nc(C)c23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H21 compound treatment 29840.0 -17000.0 -0.98 28080.0 -11800.0 -0.89 -1.3273 -0.9989 3179775 Maybridge4_000175 Cc1cc(=O)oc2[nH]nc(CSc3ccc(Cl)cc3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H22 compound treatment 47080.0 276.0 0.02 35920.0 -3970.0 -0.3 -0.2014 -0.6685 1137912 Maybridge4_000176 CCOC(=O)c1c(C)c(C#N)c(NC(=O)c2ccc(Cl)cc2Cl)n1c3ccc(C)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H23 mock treatment 46680.0 -124.0 -0.01 42920.0 3030.0 0.23 0.1569 0.6846 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 H24 mock treatment 44480.0 -2320.0 -0.13 38400.0 -1490.0 -0.11 -0.1752 -0.9962 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I01 compound treatment 46640.0 -164.0 -0.01 36640.0 -3250.0 -0.25 -0.1809 -0.7338 3179776 Maybridge4_000177 OC(=O)C1CCc2ccccc2O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I02 compound treatment 40720.0 -6080.0 -0.35 29600.0 -10300.0 -0.78 -0.8002 -0.9357 1265650 Maybridge4_000178 OC(=O)c1ccccc1NC(=O)c2ccccc2NC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I03 compound treatment 41200.0 -5600.0 -0.32 38240.0 -1650.0 -0.13 -0.3181 -0.9141 3063239 Maybridge4_000179 COc1ccc(CC/N=C/c2ccc(Oc3nccc(n3)C(F)(F)F)cc2)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I04 compound treatment 48480.0 1680.0 0.1 36760.0 -3130.0 -0.24 -0.0991 -0.3865 3179777 Maybridge4_000180 Cc1ccc(Nc2nc3ccccc3s2)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I05 compound treatment 38520.0 -8280.0 -0.48 31200.0 -8690.0 -0.66 -0.8047 -0.988 3179778 Maybridge4_000181 FC(F)(F)c1ccnc(NCCNC(=S)NCc2ccco2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I06 compound treatment 30360.0 -16400.0 -0.95 26920.0 -13000.0 -0.98 -1.3681 -0.9999 3063240 Maybridge4_000182 Cc1ccc2N(CCCc2c1)C(=S)Nc3cccc(c3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I07 compound treatment 36560.0 -10200.0 -0.59 32320.0 -7570.0 -0.57 -0.825 -0.9999 3179779 Maybridge4_000183 Cc1ccc(cc1)S(=O)(=O)NCCNc2nccc(n2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I08 compound treatment 35960.0 -10800.0 -0.63 24680.0 -15200.0 -1.15 -1.2585 -0.9594 3063241 Maybridge4_000184 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc3[nH]nnc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I09 compound treatment 44640.0 -2160.0 -0.13 37880.0 -2010.0 -0.15 -0.1964 -0.9953 3179780 Maybridge4_000185 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCC(CC2)Nc3nccc(n3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I10 compound treatment 44600.0 -2200.0 -0.13 37040.0 -2850.0 -0.22 -0.243 -0.9685 3063242 Maybridge4_000186 Clc1ccc2scc(/C(=C/c3cccs3)/C#N)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I11 compound treatment 440.0 -46400.0 -2.69 160.0 -39700.0 -3.01 -4.0261 -0.9984 3179781 Maybridge4_000187 CCOC(=O)c1c(sc(C)c1c2ccccc2)N3C(=O)C=CC3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I12 compound treatment 31080.0 -15700.0 -0.91 20240.0 -19700.0 -1.49 -1.6961 -0.9723 3063243 Maybridge4_000188 FC(F)(F)c1cc(NC=C2C(=O)NC(=S)NC2=O)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I13 compound treatment 33840.0 -13000.0 -0.75 25640.0 -14300.0 -1.08 -1.294 -0.9843 3179782 Maybridge4_000189 Cc1nc(ccc1c2nnc(SCCCN3C(=O)c4ccccc4C3=O)o2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I14 compound treatment 19680.0 -27100.0 -1.57 17520.0 -22400.0 -1.69 -2.3087 -0.9993 3179783 Maybridge4_000190 Cc1nc2ccc(Br)cc2c(=O)n1c3cc(ccc3N4CCOCC4)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I15 compound treatment 13280.0 -33500.0 -1.94 10880.0 -29000.0 -2.2 -2.9263 -0.9981 1704168 Maybridge4_000191 CC1(C)C2CCC1(CS(=O)(=O)N3CCCN(CC3)c4nc5ccc(Cl)cc5s4)C(=O)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I16 compound treatment 38320.0 -8480.0 -0.49 28200.0 -11700.0 -0.89 -0.9735 -0.9615 3179784 Maybridge4_000192 COc1ccccc1NC(=O)CSc2cc(cc(c2)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I17 compound treatment 37840.0 -8960.0 -0.52 30440.0 -9450.0 -0.72 -0.8732 -0.9876 1335897 Maybridge4_000193 Clc1cc(ccc1N2C(=O)CC3(CCCC3)C2=O)S(=O)(=O)N4CCc5ccccc5C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I18 compound treatment 32080.0 -14700.0 -0.85 22120.0 -17800.0 -1.35 -1.5545 -0.9758 3063244 Maybridge4_000194 Cc1cccc(C)c1NC(=O)CSC(=O)c2sc3ccccc3c2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I19 compound treatment 36480.0 -10300.0 -0.6 30160.0 -9730.0 -0.74 -0.9439 -0.9946 3179785 Maybridge4_000195 FC(F)(F)c1cc(Cl)c2nc(cn2c1)C(=O)NCCCN3CCN(Cc4ccccc4)CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I20 compound treatment 30360.0 -16400.0 -0.95 26480.0 -13400.0 -1.02 -1.3916 -0.9995 3063245 Maybridge4_000196 Cc1ccc2ncc(nc2c1)c3ccc(Cl)c(C)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I21 compound treatment 36400.0 -10400.0 -0.6 32000.0 -7890.0 -0.6 -0.8487 -1.0 3063246 Maybridge4_000197 CN(C)/N=C(\C)/c1cc(Cl)cc(Cl)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I22 compound treatment 53320.0 6520.0 0.38 37000.0 -2890.0 -0.22 0.1121 0.2568 3179786 Maybridge4_000198 Cc1nc2c(Br)cc(Br)cc2c(=O)n1Cc3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I23 mock treatment 45120.0 -1680.0 -0.1 42840.0 2950.0 0.22 0.0887 0.3645 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 I24 mock treatment 46240.0 -564.0 -0.03 42520.0 2630.0 0.2 0.1175 0.5831 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J01 compound treatment 43160.0 -3640.0 -0.21 35600.0 -4290.0 -0.33 -0.3791 -0.9782 3063247 Maybridge4_000199 CSC1=NCCCN1C(=O)c2c(C)onc2c3ccccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J02 compound treatment 44560.0 -2240.0 -0.13 39640.0 -254.0 -0.02 -0.1055 -0.8029 3179787 Maybridge4_000200 FC(F)(F)C1=NN(C(=O)C1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J03 compound treatment 51200.0 4400.0 0.25 37520.0 -2370.0 -0.18 0.0531 0.1702 3063248 Maybridge4_000201 Cc1cc(ccc1Cl)C2=Nc3ccccc3SC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J04 compound treatment 45280.0 -1520.0 -0.09 42000.0 2110.0 0.16 0.0503 0.2761 3179788 Maybridge4_000202 Cc1ccc(=O)n(n1)S(=O)(=O)c2ccc(F)cc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J05 compound treatment 40880.0 -5920.0 -0.34 34800.0 -5090.0 -0.39 -0.5153 -0.9983 3063249 Maybridge4_000203 CC(C)(C)NC(=S)NC1CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J06 compound treatment 38920.0 -7880.0 -0.46 36960.0 -2930.0 -0.22 -0.48 -0.9451 1412882 Maybridge4_000204 CN(NS(=O)(=O)c1ccc(Cl)cc1)c2cnn(C)c(=O)c2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J07 compound treatment 38200.0 -8600.0 -0.5 30040.0 -9850.0 -0.75 -0.8799 -0.9808 3179789 Maybridge4_000205 CC1CN(CC(C)O1)C2=NCCN2S(=O)(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J08 compound treatment 45000.0 -1800.0 -0.1 38120.0 -1770.0 -0.13 -0.1688 -0.9923 3063250 Maybridge4_000206 COC(=O)c1cc(OC(=O)c2nn(nc2C)c3ccccc3)n(n1)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J09 compound treatment 42160.0 -4640.0 -0.27 33560.0 -6330.0 -0.48 -0.5293 -0.9627 3179790 Maybridge4_000207 FC(F)(F)c1ccc(OC(=O)NC(=O)c2c(Cl)cccc2Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J10 compound treatment 32920.0 -13900.0 -0.8 24160.0 -15700.0 -1.19 -1.4109 -0.9817 1174991 Maybridge4_000208 Clc1ccc(NC(=O)N2CCC(CC2)C(c3ccccc3)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J11 compound treatment 15600.0 -31200.0 -1.81 10720.0 -29200.0 -2.21 -2.8399 -0.9951 1235401 Maybridge4_000209 Cc1cc(Oc2ccnc3cc(Cl)ccc23)ccc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J12 compound treatment 18280.0 -28500.0 -1.65 16120.0 -23800.0 -1.8 -2.441 -0.9991 1558885 Maybridge4_000210 Cc1cc(cc(C)c1OC(=O)Nc2ccc(Cl)cc2)c3nn(C)c(=O)c4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J13 compound treatment 32440.0 -14400.0 -0.83 28840.0 -11100.0 -0.84 -1.1801 -1.0 1586134 Maybridge4_000211 Clc1cccc(Cl)c1C(=O)NC(=O)N(Cc2ccccc2)C3CC4CCC3C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J14 compound treatment 38280.0 -8520.0 -0.49 30960.0 -8930.0 -0.68 -0.8274 -0.9881 3178204 Maybridge4_000212 CN(C)/C=C(\C(=O)Nc1ccc(F)c(F)c1F)/S(=O)(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J15 compound treatment 45120.0 -1680.0 -0.1 33960.0 -5930.0 -0.45 -0.3866 -0.8411 1175614 Maybridge4_000213 O=c1ncn(Cc2ccccn2)cc1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J16 compound treatment 41040.0 -5760.0 -0.33 33040.0 -6850.0 -0.52 -0.603 -0.9773 1210252 Maybridge4_000214 Cc1ccc(cc1)C(=O)COc2cc(C)nc3nncn23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J17 compound treatment 43200.0 -3600.0 -0.21 36560.0 -3330.0 -0.25 -0.3261 -0.9956 1235603 Maybridge4_000215 Fc1ccc(NC(=O)Cc2nn[nH]n2)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J18 compound treatment 22240.0 -24600.0 -1.42 18760.0 -21100.0 -1.6 -2.1375 -0.9983 1578276 Maybridge4_000216 CN(c1cnn(c2ccc(C)cc2)c(=O)c1Cl)n3cccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J19 compound treatment 40760.0 -6040.0 -0.35 38920.0 -974.0 -0.07 -0.2997 -0.8376 1321013 Maybridge4_000217 COC(=O)c1sccc1OC(=O)c2nn(nc2C)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J20 compound treatment 45280.0 -1520.0 -0.09 32840.0 -7050.0 -0.53 -0.44 -0.813 3063294 Maybridge4_000218 Cc1ccc(/C=C/c2onc3c(=O)n(C)nc(C)c23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J21 compound treatment 21560.0 -25200.0 -1.46 13400.0 -26500.0 -2.01 -2.4522 -0.988 3063295 Maybridge4_000219 CCCC/1=NN(C(=O)\C1=C\c2ccc(Cl)cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J22 compound treatment 26440.0 -20400.0 -1.18 19760.0 -20100.0 -1.52 -1.9119 -0.992 3063296 Maybridge4_000220 CN(C(=O)CSc1ccc(cn1)C(F)(F)F)c2c3CCCCc3nn2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J23 mock treatment 43240.0 -3560.0 -0.21 37800.0 -2090.0 -0.16 -0.2581 -0.9915 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 J24 mock treatment 48120.0 1320.0 0.08 40920.0 1030.0 0.08 0.1089 1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K01 compound treatment 12840.0 -34000.0 -1.97 8240.0 -31700.0 -2.4 -3.0857 -0.9952 1220864 Maybridge4_000221 CC(C)(C)c1cc(CN2C(=O)c3ccccc3C2=O)cc(c1O)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K02 compound treatment 39880.0 -6920.0 -0.4 31240.0 -8650.0 -0.66 -0.7468 -0.9723 3063297 Maybridge4_000222 Cc1cc2CSC(SCc2cc1C)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K03 compound treatment 26720.0 -20100.0 -1.16 26960.0 -12900.0 -0.98 -1.5151 -0.9963 3178205 Maybridge4_000223 FC(F)(F)Oc1ccc(cc1)N2C(=O)CC3(CCCC3)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K04 compound treatment 33520.0 -13300.0 -0.77 30400.0 -9490.0 -0.72 -1.0524 -0.9994 3063298 Maybridge4_000224 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc3oc(=O)ccc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K05 compound treatment 30320.0 -16500.0 -0.96 24080.0 -15800.0 -1.2 -1.5217 -0.9937 3178206 Maybridge4_000225 FC(F)(F)c1ccc(/C=C(\C#N)/c2cccc(c2)C(F)(F)F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K06 compound treatment 7720.0 -39100.0 -2.26 6840.0 -33100.0 -2.5 -3.3704 -0.9988 1672405 Maybridge4_000226 Clc1cccc(NC(=S)N2CCc3ccccc3C2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K07 compound treatment 31680.0 -15100.0 -0.88 20760.0 -19100.0 -1.45 -1.6437 -0.971 1231870 Maybridge4_000227 Fc1ccc(CN2CCCN(CC2)C(=O)Nc3cccc(Cl)c3Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K08 compound treatment 35920.0 -10900.0 -0.63 31120.0 -8770.0 -0.66 -0.9155 -0.9997 1729950 Maybridge4_000228 CC(C)N(Cc1ccc(cc1)N(C)C)C(=O)c2sc3ccccc3c2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K09 compound treatment 1200.0 -45600.0 -2.64 1480.0 -38400.0 -2.91 -3.9244 -0.9989 3178207 Maybridge4_000229 Cc1nc(ccc1C(=O)N2CCN(CC2)c3nc4ccc(Cl)cc4s3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K10 compound treatment 33880.0 -12900.0 -0.75 23240.0 -16700.0 -1.26 -1.4208 -0.9691 1285643 Maybridge4_000230 Clc1ccc(cc1)N(CCc2ccccn2)S(=O)(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K11 compound treatment 18160.0 -28600.0 -1.66 13200.0 -26700.0 -2.02 -2.6022 -0.9952 3063299 Maybridge4_000231 Clc1ccc(Cl)c(c1)n2ccnc2SCCCN3C(=O)c4ccccc4C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K12 compound treatment 36920.0 -9880.0 -0.57 27000.0 -12900.0 -0.98 -1.095 -0.9677 1594434 Maybridge4_000232 COc1ccc(cc1)C(=O)CC2(O)C(=O)N(CN3CCOCC3)c4ccc(Br)cc42 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K13 compound treatment 31880.0 -14900.0 -0.86 27400.0 -12500.0 -0.95 -1.2801 -0.999 3063300 Maybridge4_000233 Cc1ccc(cc1)S(=O)(=O)NC(=O)NC2CCN(CC2)c3nccc(n3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K14 compound treatment 29520.0 -17300.0 -1.0 19360.0 -20500.0 -1.55 -1.8071 -0.9774 1540061 Maybridge4_000234 CN1C(NC(=O)c2ccccc12)C3CCC=CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K15 compound treatment 1080.0 -45700.0 -2.65 1040.0 -38900.0 -2.94 -3.9528 -0.9986 3178208 Maybridge4_000235 CC(C)Nc1ncnc2scc(c3ccccc3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K16 compound treatment 25480.0 -21300.0 -1.24 23040.0 -16900.0 -1.28 -1.7757 -0.9999 3063301 Maybridge4_000236 S=C(NCCCN1CCOCC1)N2CC3CCC(CC3)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K17 compound treatment 14880.0 -31900.0 -1.85 9800.0 -30100.0 -2.28 -2.9186 -0.9947 1631820 Maybridge4_000237 COc1ccc(NS(=O)(=O)c2ccc(N3C(=O)CC4(CCCC4)C3=O)c(Cl)c2)c(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K18 compound treatment 28000.0 -18800.0 -1.09 21640.0 -18300.0 -1.38 -1.7474 -0.9931 3063302 Maybridge4_000238 Cc1cc(Oc2ccc(cc2n3cccc3)C(F)(F)F)cc(C)c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K19 compound treatment 7360.0 -39400.0 -2.29 4920.0 -35000.0 -2.65 -3.4879 -0.9973 3178209 Maybridge4_000239 FC(F)(F)c1cnc(N2CCC(CC2)N3C(=O)CC4(CCCC4)C3=O)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K20 compound treatment 32480.0 -14300.0 -0.83 25840.0 -14100.0 -1.06 -1.339 -0.9925 3063303 Maybridge4_000240 Clc1ccc(SC(=O)c2cccnc2Oc3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K21 compound treatment 23120.0 -23700.0 -1.37 17840.0 -22100.0 -1.67 -2.1507 -0.9953 1673449 Maybridge4_000241 O=C1CCCCCCCCCCC1CN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K22 compound treatment 36200.0 -10600.0 -0.61 29840.0 -10100.0 -0.76 -0.9725 -0.9944 1443277 Maybridge4_000242 Nc1ccccc1C(=O)NCCc2ccncc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K23 mock treatment 43520.0 -3280.0 -0.19 29960.0 -9930.0 -0.75 -0.6662 -0.859 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 K24 mock treatment 33880.0 -12900.0 -0.75 32840.0 -7050.0 -0.53 -0.907 -0.9863 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L01 compound treatment 44040.0 -2760.0 -0.16 34920.0 -4970.0 -0.38 -0.3794 -0.9275 1275035 Maybridge4_000243 COC(=O)c1ccc(C)c(NC(=O)c2ccncc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L02 compound treatment 38480.0 -8320.0 -0.48 29120.0 -10800.0 -0.82 -0.9177 -0.9686 3178210 Maybridge4_000244 CN(C)/C=N/S(=O)(=O)c1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L03 compound treatment 21640.0 -25200.0 -1.46 22120.0 -17800.0 -1.35 -1.9822 -0.9992 1520487 Maybridge4_000245 Clc1ccc(cc1)C(=O)CNC(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L04 compound treatment 37680.0 -9120.0 -0.53 34320.0 -5570.0 -0.42 -0.6721 -0.9938 3063304 Maybridge4_000246 Fc1ccc(cc1F)C2=CSC3=NCCCN23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L05 compound treatment 24200.0 -22600.0 -1.31 21160.0 -18700.0 -1.42 -1.9287 -0.9992 3178211 Maybridge4_000247 CCC1(CC)N/C(=N/c2ccc(F)cc2F)/SC1=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L06 compound treatment 2000.0 -44800.0 -2.6 1600.0 -38300.0 -2.9 -3.8852 -0.9985 3063305 Maybridge4_000248 Cn1ncc(SCc2ccccc2)c(Cl)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L07 compound treatment 31360.0 -15400.0 -0.89 29120.0 -10800.0 -0.82 -1.2094 -0.9989 3178212 Maybridge4_000249 Cc1ccc(/N=C\2/NC(C)(C)C(=C)S2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L08 compound treatment 30840.0 -16000.0 -0.92 26800.0 -13100.0 -0.99 -1.3548 -0.9994 3178213 Maybridge4_000250 CC(=O)Nc1ccc(Oc2cncc(Cl)c2)nc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L09 compound treatment 39160.0 -7640.0 -0.44 31680.0 -8210.0 -0.62 -0.7528 -0.9862 3063306 Maybridge4_000251 CCOC(=S)SCc1ccc(cc1)C(=O)Oc2ccc(F)cc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L10 compound treatment 35560.0 -11200.0 -0.65 26520.0 -13400.0 -1.01 -1.1765 -0.9773 3178214 Maybridge4_000252 CC1(C)CN(C(=S)Nc2cccc(Cl)c2)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L11 compound treatment 32160.0 -14600.0 -0.85 27840.0 -12100.0 -0.91 -1.2451 -0.9993 3063307 Maybridge4_000253 COC(=O)/C=C/1\S/C(=N\c2ccccn2)/N(C1=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L12 compound treatment 36760.0 -10000.0 -0.58 29320.0 -10600.0 -0.8 -0.9774 -0.9877 1389325 Maybridge4_000254 Cc1cc(cc(C)c1OCC(=O)NN)c2nn(C)c(=O)c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L13 compound treatment 33440.0 -13400.0 -0.77 20520.0 -19400.0 -1.47 -1.5844 -0.9554 3063308 Maybridge4_000255 CSc1ccc(OCOc2ccc(SC)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L14 compound treatment 33360.0 -13400.0 -0.78 24480.0 -15400.0 -1.17 -1.3758 -0.9807 3178215 Maybridge4_000256 CCOC(=O)c1c(F)c(F)c(c(F)c1F)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L15 compound treatment 28920.0 -17900.0 -1.04 20160.0 -19700.0 -1.49 -1.7889 -0.984 3178216 Maybridge4_000257 CN1C(NC(=O)c2cc(Cl)ccc12)c3ccc(C#N)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L16 compound treatment 41600.0 -5200.0 -0.3 33680.0 -6210.0 -0.47 -0.5458 -0.9769 1354966 Maybridge4_000258 Cc1ccc(Oc2ncccc2C(=O)NCC(=O)O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L17 compound treatment 24760.0 -22000.0 -1.28 20200.0 -19700.0 -1.49 -1.9572 -0.997 3178217 Maybridge4_000259 NC(=O)Nc1ccc2[nH]ncc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L18 compound treatment 42440.0 -4360.0 -0.25 36880.0 -3010.0 -0.23 -0.3401 -0.9987 3063309 Maybridge4_000260 COc1cc(C)nc2nc(nn12)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L19 compound treatment 35960.0 -10800.0 -0.63 32560.0 -7330.0 -0.56 -0.8368 -0.9981 3178218 Maybridge4_000261 CSc1nncc(n1)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L20 compound treatment 34200.0 -12600.0 -0.73 27760.0 -12100.0 -0.92 -1.1658 -0.9935 1483914 Maybridge4_000262 Cc1ccc(cc1)c2cc(n[nH]2)c3c(C)nn(C)c(=O)c3N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L21 compound treatment 37880.0 -8920.0 -0.52 36680.0 -3210.0 -0.24 -0.5376 -0.9409 1521640 Maybridge4_000263 Nc1ccccc1C(=O)NC2CCCCNC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L22 compound treatment 21840.0 -25000.0 -1.45 17640.0 -22300.0 -1.68 -2.2138 -0.9971 3178219 Maybridge4_000264 Cc1nc(cs1)c2cc(C#N)c(Sc3cccc(c3)C(F)(F)F)nc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L23 mock treatment 48520.0 1720.0 0.1 33000.0 -6890.0 -0.52 -0.2987 -0.5622 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 L24 mock treatment 42560.0 -4240.0 -0.25 34920.0 -4970.0 -0.38 -0.4401 -0.9787 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M01 compound treatment 41720.0 -5080.0 -0.29 36080.0 -3810.0 -0.29 -0.4124 -0.9999 3063310 Maybridge4_000265 Oc1ccccc1/N=C/C=N/c2ccccc2O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M02 compound treatment 80680.0 33900.0 1.96 55560.0 15700.0 1.19 2.2264 0.9709 3178220 Maybridge4_000266 CN(CCC#N)c1ccc(cc1)C2SCc3cc(C)c(C)cc3CS2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M03 compound treatment 42600.0 -4200.0 -0.24 36720.0 -3170.0 -0.24 -0.3421 -1.0 3063311 Maybridge4_000267 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCCN(CC2)c3ccc(cn3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M04 compound treatment 47360.0 556.0 0.03 39680.0 -214.0 -0.02 0.0113 0.3147 3178221 Maybridge4_000268 Cc1onc(c1C(=O)N2CCCc3cccc(C)c23)c4c(Cl)cccc4Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M05 compound treatment 1720.0 -45100.0 -2.61 1480.0 -38400.0 -2.91 -3.9031 -0.9986 1280324 Maybridge4_000269 Cc1c(Cl)cccc1NC(=S)N2CCCN(CC2)c3nc4ccc(Cl)cc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M06 compound treatment 36640.0 -10200.0 -0.59 35480.0 -4410.0 -0.33 -0.6526 -0.964 1592820 Maybridge4_000270 Cc1ccccc1NC(=S)Nc2ccccc2C(=O)Nc3ccc(F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M07 compound treatment 40000.0 -6800.0 -0.39 32000.0 -7890.0 -0.6 -0.7012 -0.9796 3178222 Maybridge4_000271 Cc1nc(ccc1C(=O)Oc2ccc(OC(F)(F)F)cc2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M08 compound treatment 32960.0 -13800.0 -0.8 29800.0 -10100.0 -0.76 -1.1074 -0.9997 1647940 Maybridge4_000272 Cc1cc(OCc2c(C)c(C)c(C)c(C)c2C)c3cc(Cl)ccc3n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M09 compound treatment 32040.0 -14800.0 -0.86 30000.0 -9890.0 -0.75 -1.1344 -0.9978 3178223 Maybridge4_000273 Cc1ccc(NC(=S)N2CCC(CC2)Nc3nccc(n3)C(F)(F)F)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M10 compound treatment 22160.0 -24600.0 -1.43 19760.0 -20100.0 -1.52 -2.0872 -0.9995 1291651 Maybridge4_000274 CC(C)c1ccc(cc1)N(CCc2ccccn2)S(=O)(=O)c3ccc(C)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M11 compound treatment 1240.0 -45600.0 -2.64 1600.0 -38300.0 -2.9 -3.9163 -0.9989 3178308 Maybridge4_000275 FC(F)(F)c1cccnc1NCCNc2ncnc3scc(c4ccccc4)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M12 compound treatment 21240.0 -25600.0 -1.48 15520.0 -24400.0 -1.84 -2.3519 -0.9941 3178309 Maybridge4_000276 Fc1ccc(cc1)C2CN3C(=N2)C=Cc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M13 compound treatment 24640.0 -22200.0 -1.28 22480.0 -17400.0 -1.32 -1.8401 -0.9999 1327290 Maybridge4_000277 COC(=O)c1cc(C#N)c(C)nc1Sc2nccn2c3cc(Cl)ccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M14 compound treatment 34320.0 -12500.0 -0.72 23960.0 -15900.0 -1.21 -1.3643 -0.9701 1331303 Maybridge4_000278 O=C1NC(Nc2ccccc12)C3CCC=CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M15 compound treatment 32160.0 -14600.0 -0.85 24680.0 -15200.0 -1.15 -1.4142 -0.9887 1371250 Maybridge4_000279 CC(C)NS(=O)(=O)c1ccc(N2C(=O)CC3(CCCC3)C2=O)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M16 compound treatment 37840.0 -8960.0 -0.52 24640.0 -15300.0 -1.15 -1.1837 -0.9349 1643068 Maybridge4_000280 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)N2CC3CCC(CC3)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M17 compound treatment 26240.0 -20600.0 -1.19 21320.0 -18600.0 -1.41 -1.8366 -0.9966 1732462 Maybridge4_000281 CCOC(=O)C1CCN(CC1)S(=O)(=O)c2ccc(N3C(=O)CC4(CCCC4)C3=O)c(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M18 compound treatment 37040.0 -9760.0 -0.57 26640.0 -13300.0 -1.0 -1.1094 -0.9632 1423781 Maybridge4_000282 Cc1cc(ccc1Cl)C(=O)c2cc3cc(Cl)ccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M19 compound treatment 1520.0 -45300.0 -2.62 1560.0 -38300.0 -2.9 -3.907 -0.9987 3178310 Maybridge4_000283 Fc1cccc(Cl)c1CN2CCN(CCCNc3ncnc4scc(c5ccccc5)c34)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M20 compound treatment 27920.0 -18900.0 -1.09 19360.0 -20500.0 -1.55 -1.8727 -0.9852 3063131 Maybridge4_000284 NNC(=O)c1cccnc1Oc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M21 compound treatment 38440.0 -8360.0 -0.48 36560.0 -3330.0 -0.25 -0.5211 -0.9538 3063132 Maybridge4_000285 Fc1ccc(/C=C/c2cccc3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M22 compound treatment 33200.0 -13600.0 -0.79 27800.0 -12100.0 -0.92 -1.2046 -0.9972 3178311 Maybridge4_000286 Cc1ccc(SCCNC(=O)c2cccnc2Oc3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M23 mock treatment 43960.0 -2840.0 -0.16 33680.0 -6210.0 -0.47 -0.4491 -0.9011 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 M24 mock treatment 45400.0 -1400.0 -0.08 34080.0 -5810.0 -0.44 -0.3687 -0.8238 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N01 compound treatment 22120.0 -24700.0 -1.43 17560.0 -22300.0 -1.69 -2.2066 -0.9965 1041669 Maybridge4_000287 O=C(CSCC(=O)c1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N02 compound treatment 41120.0 -5680.0 -0.33 37200.0 -2690.0 -0.2 -0.377 -0.9734 3178312 Maybridge4_000288 COC(=O)c1cccnc1SC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N03 compound treatment 43880.0 -2920.0 -0.17 35840.0 -4050.0 -0.31 -0.3368 -0.9608 3063133 Maybridge4_000289 Cc1ccccc1c2ncc(o2)c3ccc(Br)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N04 compound treatment 51800.0 5000.0 0.29 35480.0 -4410.0 -0.33 -0.0316 -0.0714 3178313 Maybridge4_000290 Fc1ccc(cc1F)C2=NNC3=NCCN3C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N05 compound treatment 30880.0 -15900.0 -0.92 26920.0 -13000.0 -0.98 -1.3468 -0.9995 3178314 Maybridge4_000291 Clc1ccc(NC(=N)c2ccccc2)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N06 compound treatment 36400.0 -10400.0 -0.6 32480.0 -7410.0 -0.56 -0.823 -0.9994 1155893 Maybridge4_000292 CSc1nnc(SC)n1CCNC(=O)c2c(Cl)cccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N07 compound treatment 27160.0 -19600.0 -1.14 24600.0 -15300.0 -1.16 -1.6234 -1.0 3178315 Maybridge4_000293 CCc1cccc(CC)c1/N=C\2/NC(C)(C)C(=C)S2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N08 compound treatment 34160.0 -12600.0 -0.73 30760.0 -9130.0 -0.69 -1.0069 -0.9996 3178316 Maybridge4_000294 FC(F)(F)c1ccc(nc1)S(=O)(=O)CC2=NN(C(=O)C2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N09 compound treatment 30880.0 -15900.0 -0.92 28040.0 -11900.0 -0.9 -1.2868 -0.9999 1286323 Maybridge4_000295 COC(=O)c1sc2ccccc2c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N10 compound treatment 35880.0 -10900.0 -0.63 24520.0 -15400.0 -1.16 -1.2704 -0.959 1418804 Maybridge4_000296 Nc1ccccc1Nc2nc(=O)n(Cc3ccc(Cl)cc3)cc2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N11 compound treatment 18800.0 -28000.0 -1.62 13000.0 -26900.0 -2.04 -2.5867 -0.9937 1326126 Maybridge4_000297 Cc1ccc(COn2c(nc3ccccc3c2=O)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N12 compound treatment 39400.0 -7400.0 -0.43 26360.0 -13500.0 -1.02 -1.0277 -0.9253 1242548 Maybridge4_000298 Cc1ccn2c(=O)c(cnc2c1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N13 compound treatment 29040.0 -17800.0 -1.03 23920.0 -16000.0 -1.21 -1.5827 -0.9968 3178317 Maybridge4_000299 N#Cc1ccc(OCOc2ccc(C#N)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N14 compound treatment 39280.0 -7520.0 -0.44 31120.0 -8770.0 -0.66 -0.7778 -0.9792 3063134 Maybridge4_000300 CC(C)Sc1nnc(S)n1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N15 compound treatment 29760.0 -17000.0 -0.99 22880.0 -17000.0 -1.29 -1.6089 -0.9914 3178318 Maybridge4_000301 Cn1c(nc(=O)c2cc(Cl)ccc12)c3cc(Br)cs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N16 compound treatment 32840.0 -14000.0 -0.81 27520.0 -12400.0 -0.94 -1.2344 -0.9973 3178319 Maybridge4_000302 Cc1ccc(/C=C/2\N=C(OC2=O)c3ccccc3N(CC=C)S(=O)(=O)c4ccc(C)cc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N17 compound treatment 33400.0 -13400.0 -0.78 27360.0 -12500.0 -0.95 -1.22 -0.9951 3063135 Maybridge4_000303 Cc1onc(NC(=O)NC(=O)c2ccccc2F)c1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N18 compound treatment 39560.0 -7240.0 -0.42 29280.0 -10600.0 -0.8 -0.8649 -0.9541 3063136 Maybridge4_000304 CC(C)(C)OC(=O)C(C)(C)S(=O)(=O)c1ccc(cn1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N19 compound treatment 13320.0 -33500.0 -1.94 12800.0 -27100.0 -2.05 -2.8219 -0.9996 3178320 Maybridge4_000305 Clc1cc(Cl)c2nc(Oc3cccc(c3)N4CCOCC4)sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N20 compound treatment 16440.0 -30400.0 -1.76 19800.0 -20100.0 -1.52 -2.3194 -0.9974 3063137 Maybridge4_000306 CCOC(=O)c1nn(c2ccccc2)c(=N)c(C#N)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N21 compound treatment 36680.0 -10100.0 -0.59 32960.0 -6930.0 -0.52 -0.7859 -0.9985 3178321 Maybridge4_000307 Cc1nn(nc1c2nnc(o2)c3ccc(Cl)c(Cl)c3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N22 compound treatment 22080.0 -24700.0 -1.43 19560.0 -20300.0 -1.54 -2.1012 -0.9994 3178322 Maybridge4_000308 Cc1nc(cs1)c2cc(C#N)c(Oc3ccc(cc3)C(F)(F)F)nc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N23 mock treatment 40160.0 -6640.0 -0.38 37200.0 -2690.0 -0.2 -0.4164 -0.9558 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 N24 mock treatment 40800.0 -6000.0 -0.35 33200.0 -6690.0 -0.51 -0.6042 -0.9832 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O01 compound treatment 45200.0 -1600.0 -0.09 37920.0 -1970.0 -0.15 -0.1713 -0.9739 3063138 Maybridge4_000309 Cn1cc(c(n1)C(F)(F)F)S(=O)(=O)NCc2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O02 compound treatment 50880.0 4080.0 0.24 39520.0 -374.0 -0.03 0.147 0.618 1336600 Maybridge4_000310 Clc1ccccc1n2c(n[nH]c2=S)C3CCCNC3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O03 compound treatment 33600.0 -13200.0 -0.76 28480.0 -11400.0 -0.86 -1.1518 -0.9982 3063139 Maybridge4_000311 Cc1cccc(Cl)c1NC(=O)N2CCCN(CC2)c3ncccc3C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O04 compound treatment 17160.0 -29600.0 -1.72 10960.0 -28900.0 -2.19 -2.7631 -0.9928 3178323 Maybridge4_000312 CCOC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O05 compound treatment 42280.0 -4520.0 -0.26 34440.0 -5450.0 -0.41 -0.4772 -0.976 1600108 Maybridge4_000313 OC1CCN(CC1)C(=O)Nc2ccc(Cl)c(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O06 compound treatment 1880.0 -44900.0 -2.6 1560.0 -38300.0 -2.9 -3.8922 -0.9985 1675860 Maybridge4_000314 CCN(Cc1cc(OC)c(OC)c(OC)c1)C(=S)Nc2cccc(SC)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O07 compound treatment 45480.0 -1320.0 -0.08 34120.0 -5770.0 -0.44 -0.3633 -0.8187 3063188 Maybridge4_000315 Cc1nc(ccc1C(=O)NCC=C)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O08 compound treatment 26520.0 -20300.0 -1.18 22320.0 -17600.0 -1.33 -1.7716 -0.9981 1638858 Maybridge4_000316 Cc1nc2cc(Cl)ccc2c(=O)n1CC3CCCO3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O09 compound treatment 24440.0 -22400.0 -1.3 25880.0 -14000.0 -1.06 -1.6663 -0.9951 1730664 Maybridge4_000317 CCOC(=O)c1cc(C(=O)OC)c(C)nc1N2CCC(CC2)NC3CCCCC3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O10 compound treatment 25320.0 -21500.0 -1.24 23600.0 -16300.0 -1.23 -1.7523 -1.0 1134448 Maybridge4_000318 Fc1ccc(NC(=S)N2CCCCC2CCN3CCOCC3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O11 compound treatment 42240.0 -4560.0 -0.26 35760.0 -4130.0 -0.31 -0.4082 -0.9965 3063189 Maybridge4_000319 OC(=O)/C=C/C(=O)NC1CCN(CC1)c2nccc(n2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O12 compound treatment 38000.0 -8800.0 -0.51 31920.0 -7970.0 -0.6 -0.7875 -0.9965 3178324 Maybridge4_000320 C1C(N=C2C=Cc3ccccc3N12)c4ccc5ccccc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O13 compound treatment 24000.0 -22800.0 -1.32 20400.0 -19500.0 -1.48 -1.9776 -0.9985 1152090 Maybridge4_000321 CC1CN(CC(C)O1)S(=O)(=O)c2ccc(N3C(=O)CC4(CCCC4)C3=O)c(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O14 compound treatment 38840.0 -7960.0 -0.46 29440.0 -10500.0 -0.79 -0.8858 -0.967 1502131 Maybridge4_000322 Nc1n(nc2cc(O)nc(O)c12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O15 compound treatment 44280.0 -2520.0 -0.15 34320.0 -5570.0 -0.42 -0.4017 -0.8997 1406030 Maybridge4_000323 CC(C)(C)OC(=O)N1CCN(CC1)C(=O)c2ccccc2C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O16 compound treatment 2600.0 -44200.0 -2.56 2120.0 -37800.0 -2.86 -3.8327 -0.9985 1015155 Maybridge4_000324 O=c1ccc(=O)n([nH]1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O17 compound treatment 8160.0 -38600.0 -2.24 5480.0 -34400.0 -2.6 -3.4251 -0.9972 3178325 Maybridge4_000325 Cc1nc(nc(NC2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)c1Cl)c4ccccn4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O18 compound treatment 42640.0 -4160.0 -0.24 36400.0 -3490.0 -0.26 -0.3576 -0.9989 3063190 Maybridge4_000326 Cc1cc(NC(=S)NC(C)(C)C)ccc1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O19 compound treatment 22960.0 -23800.0 -1.38 18520.0 -21400.0 -1.62 -2.1208 -0.9969 1373262 Maybridge4_000327 S=C(NC1CC1)N2CCCN(Cc3cccc4ccccc34)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O20 compound treatment 39400.0 -7400.0 -0.43 35640.0 -4250.0 -0.32 -0.531 -0.99 3178326 Maybridge4_000328 N#Cc1cccnc1Oc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O21 compound treatment 42960.0 -3840.0 -0.22 34600.0 -5290.0 -0.4 -0.4408 -0.9616 3178327 Maybridge4_000329 Cc1cc(C(=O)NN)c2cc(Br)ccc2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O22 compound treatment 24000.0 -22800.0 -1.32 21680.0 -18200.0 -1.38 -1.9091 -0.9998 3063191 Maybridge4_000330 CC(C)(C)NC(=S)Nc1cc(ccc1N2CCCCC2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O23 mock treatment 46240.0 -564.0 -0.03 41600.0 1710.0 0.13 0.0682 0.5122 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 O24 mock treatment 46720.0 -83.8 0.0 45040.0 5150.0 0.39 0.272 0.6982 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P01 compound treatment 37600.0 -9200.0 -0.53 25120.0 -14800.0 -1.12 -1.1678 -0.9426 3178328 Maybridge4_000331 Fc1ccc(cc1Cl)C(=O)NC(=O)Nc2nnc(s2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P02 compound treatment 4040.0 -42800.0 -2.48 3520.0 -36400.0 -2.75 -3.6988 -0.9986 3178329 Maybridge4_000332 CN(C)/C=C/1\C(=O)c2ccc(Cl)cc2N(Cc3c(F)cccc3Cl)S1(=O)=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P03 compound treatment 37480.0 -9320.0 -0.54 33360.0 -6530.0 -0.49 -0.7317 -0.999 3063192 Maybridge4_000333 Fc1ccccc1C(=O)NC(=O)OCc2ccc(Cl)cc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P04 compound treatment 40600.0 -6200.0 -0.36 31600.0 -8290.0 -0.63 -0.6981 -0.965 3063193 Maybridge4_000334 CN1N=C(CC1=O)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P05 compound treatment 40280.0 -6520.0 -0.38 29040.0 -10900.0 -0.82 -0.8482 -0.9379 3178330 Maybridge4_000335 Clc1ccc(cc1)S(=O)(=O)Nc2ccccc2C(=O)NCCCn3ccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P06 compound treatment 36440.0 -10400.0 -0.6 27320.0 -12600.0 -0.95 -1.0976 -0.9753 3063194 Maybridge4_000336 CN(C)/C=N/c1cc(Cl)c(cc1Oc2ccc(Cl)cc2)n3cccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P07 compound treatment 36000.0 -10800.0 -0.63 28840.0 -11100.0 -0.84 -1.0343 -0.9898 3178331 Maybridge4_000337 CSC1=NCCN1CC(=O)c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P08 compound treatment 37040.0 -9760.0 -0.57 32120.0 -7770.0 -0.59 -0.8161 -0.9998 3178429 Maybridge4_000338 Oc1c(C(=O)c2ccccc2)c(CS(=O)(=O)c3ccc(cn3)C(F)(F)F)nn1c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P09 compound treatment 12440.0 -34400.0 -1.99 14920.0 -25000.0 -1.89 -2.7445 -0.9997 3063195 Maybridge4_000339 FC(F)(F)c1ccc2[nH]c(SCc3cccc(C#N)c3)nc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P10 compound treatment 31280.0 -15500.0 -0.9 24960.0 -14900.0 -1.13 -1.4353 -0.9936 3178430 Maybridge4_000340 COc1ccccc1N2CC(C)(C)C(=O)N(C(=O)c3ccc(C)cc3)C2=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P11 compound treatment 3080.0 -43700.0 -2.53 3200.0 -36700.0 -2.78 -3.7553 -0.9989 1567114 Maybridge4_000341 Brc1ccc(COn2c(nc3ccccc3c2=O)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P12 compound treatment 41480.0 -5320.0 -0.31 33200.0 -6690.0 -0.51 -0.5764 -0.9717 1250229 Maybridge4_000342 CCCCN1C(C(=O)N(C1=O)c2nnc(s2)C(C)(C)C)c3ccc(Cl)c(Cl)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P13 compound treatment 35640.0 -11200.0 -0.65 31240.0 -8650.0 -0.66 -0.9205 -1.0 3063196 Maybridge4_000343 COC(=O)/C=c/1\sc2nc3cc(Cl)c(Cl)cc3n2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P14 compound treatment 6120.0 -40700.0 -2.36 6640.0 -33300.0 -2.52 -3.4466 -0.9995 3178431 Maybridge4_000344 FC(F)(F)c1ccc(nc1)S(=O)(=O)CCOC(=O)c2ccc(Cl)c(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P15 compound treatment 28880.0 -17900.0 -1.04 27920.0 -12000.0 -0.91 -1.3752 -0.9977 3063197 Maybridge4_000345 CC(C)(C)SCCNc1nc(Oc2ccc(F)cc2)nc(Oc3ccc(F)cc3)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P16 compound treatment 32040.0 -14800.0 -0.86 29000.0 -10900.0 -0.82 -1.1879 -0.9998 3178432 Maybridge4_000346 N=C1CC(=O)N=C2SC(=NN21)C3CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P17 compound treatment 17760.0 -29000.0 -1.68 14840.0 -25100.0 -1.9 -2.5308 -0.9982 3063198 Maybridge4_000347 COC(=O)/C(=C/N(C)C)/Sc1cc(C)c(Cl)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P18 compound treatment 11200.0 -35600.0 -2.06 9160.0 -30700.0 -2.33 -3.1036 -0.9982 3178433 Maybridge4_000348 CSc1nc(C)nc(Sc2ccccc2)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P19 compound treatment 34920.0 -11900.0 -0.69 31320.0 -8570.0 -0.65 -0.9458 -0.9996 3178434 Maybridge4_000349 Cc1cc(Oc2nc3cc(Cl)ccc3s2)c4cc(Cl)ccc4n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P20 compound treatment 34160.0 -12600.0 -0.73 35360.0 -4530.0 -0.34 -0.7607 -0.9403 1222979 Maybridge4_000350 CSC1=NN(C)c2cnn(C)c(=O)c2S1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P21 compound treatment 36320.0 -10500.0 -0.61 36520.0 -3370.0 -0.26 -0.6101 -0.9259 1579106 Maybridge4_000351 O=C(CC#N)NCc1ccccn1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P22 compound treatment 38720.0 -8080.0 -0.47 31960.0 -7930.0 -0.6 -0.7558 -0.9924 1689187 Maybridge4_000352 Clc1ccc(SCC(=O)c2ccc3NC(=O)CCc3c2)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P23 mock treatment 39040.0 -7760.0 -0.45 35320.0 -4570.0 -0.35 -0.5629 -0.9916 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2049 P24 mock treatment 41960.0 -4840.0 -0.28 34920.0 -4970.0 -0.38 -0.4647 -0.9895 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A01 compound treatment 51800.0 10200.0 0.59 50520.0 7230.0 0.55 0.8057 0.9992 3063199 Maybridge4_000353 O=C1CCc2cc(ccc2N1)C3=CSC4=NCCN34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A02 compound treatment 30040.0 -11500.0 -0.67 35040.0 -8260.0 -0.62 -0.9143 -0.9994 3178435 Maybridge4_000354 CC1(C)OC(=O)C(C2C3CC4CC(C3)CC2C4)C(=O)O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A03 compound treatment 16120.0 -25500.0 -1.47 17400.0 -25900.0 -1.96 -2.4287 -0.9902 3178436 Maybridge4_000355 Cc1nc(cs1)c2cc(C#N)c(SCCNC(=O)c3ccc(Cl)cc3Cl)nc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A04 compound treatment 17840.0 -23700.0 -1.38 15680.0 -27600.0 -2.09 -2.4503 -0.9794 1602887 Maybridge4_000356 CC1(C)Oc2c(C=C1)c3c(=O)cc(oc3c4ccoc24)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A05 compound treatment 40320.0 -1250.0 -0.07 48800.0 5510.0 0.42 0.2433 0.5753 3063200 Maybridge4_000357 COc1cc(OC)nc(/N=C/N(C)C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A06 compound treatment 46240.0 4670.0 0.27 46160.0 2870.0 0.22 0.3446 0.994 3178437 Maybridge4_000358 CC1(C)CN=C(NC2CCCCC2)S1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A07 compound treatment 34560.0 -7010.0 -0.41 38800.0 -4500.0 -0.34 -0.5279 -0.9961 3178438 Maybridge4_000359 COc1ccc(CCC(=O)CCc2ccc(OC)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A08 compound treatment 39760.0 -1810.0 -0.11 45960.0 2670.0 0.2 0.0684 0.3007 3063201 Maybridge4_000360 COc1ccccc1OC(=O)NC(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A09 compound treatment 37160.0 -4410.0 -0.26 36800.0 -6500.0 -0.49 -0.5284 -0.9536 3178439 Maybridge4_000361 CCOC(=O)c1ccc(cc1)C(=S)N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A10 compound treatment 10000.0 -31600.0 -1.83 14000.0 -29300.0 -2.22 -2.8615 -0.9954 1174208 Maybridge4_000362 CCC1(CCCCN(C)C1=O)c2cccc(OC(=O)C3CCCCC3)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A11 compound treatment 44320.0 2750.0 0.16 43040.0 -255.0 -0.02 0.0989 0.6168 3063202 Maybridge4_000363 CN(C)Cc1c(C)cc(C)cc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A12 compound treatment 5600.0 -36000.0 -2.08 4400.0 -38900.0 -2.94 -3.5555 -0.9857 1469863 Maybridge4_000364 O=C(Nc1nc(cs1)c2ccccc2)C3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A13 compound treatment 38040.0 -3530.0 -0.2 43920.0 625.0 0.05 -0.1113 -0.5297 1002608 Maybridge4_000365 CCOC(=O)c1cnc(S)nc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A14 compound treatment 36280.0 -5290.0 -0.31 39520.0 -3780.0 -0.29 -0.4189 -0.9994 1583969 Maybridge4_000366 Clc1cccc(c1)C(=O)NC2CN3CCC2CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A15 compound treatment 22160.0 -19400.0 -1.12 25160.0 -18100.0 -1.37 -1.766 -0.9951 3063203 Maybridge4_000367 COc1cc(C#N)c2ccc3ccccc3c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A16 compound treatment 36080.0 -5490.0 -0.32 38320.0 -4980.0 -0.38 -0.4913 -0.9965 3178440 Maybridge4_000368 CCNC(=Nc1ccc(Cl)cc1)NCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A17 compound treatment 27040.0 -14500.0 -0.84 26720.0 -16600.0 -1.25 -1.4825 -0.9812 1368926 Maybridge4_000369 CC(=O)OCc1ccccc1Sc2ccccc2C(=O)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A18 compound treatment 43560.0 1990.0 0.12 42640.0 -655.0 -0.05 0.0464 0.3698 1219932 Maybridge4_000370 C1C=C(Nc2nnnn12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A19 compound treatment 21000.0 -20600.0 -1.19 23280.0 -20000.0 -1.52 -1.9141 -0.993 1528436 Maybridge4_000371 Cn1c(nc2ccccc12)N3C(=O)c4cccc5cccc(C3=O)c45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A20 compound treatment 47320.0 5750.0 0.33 45800.0 2510.0 0.19 0.3695 0.9644 1375750 Maybridge4_000372 CC1(CC2CC3(C)C1)CC(C2)(C3)C(=O)NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A21 compound treatment 45400.0 3830.0 0.22 45040.0 1750.0 0.13 0.2502 0.9694 1405005 Maybridge4_000373 O=c1nc2sc3ccccc3n2c(=O)n1c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A22 compound treatment 42520.0 948.0 0.05 51880.0 8590.0 0.65 0.4983 0.7641 3063251 Maybridge4_000374 C/S(=N\S(=O)(=O)c1ccc(Cl)cc1)/c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A23 mock treatment 49720.0 8150.0 0.47 46000.0 2710.0 0.2 0.4786 0.9301 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 A24 mock treatment 51240.0 9670.0 0.56 50000.0 6710.0 0.51 0.7549 0.9988 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B01 compound treatment 44800.0 3230.0 0.19 46200.0 2910.0 0.22 0.2877 0.9967 3063252 Maybridge4_000375 C1CN(C1)C(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B02 compound treatment 51520.0 9950.0 0.58 52240.0 8950.0 0.68 0.8863 0.9968 3063253 Maybridge4_000376 CC1CCC(C)N1c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B03 compound treatment 50280.0 8710.0 0.5 49920.0 6630.0 0.5 0.7113 1.0 3063254 Maybridge4_000377 Cc1ccc(cc1)S(=O)(=O)C[C@H]2O[C@H](C[C@@H]2O)n3cc(I)c(=O)[nH]c3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B04 compound treatment 39120.0 -2450.0 -0.14 39840.0 -3460.0 -0.26 -0.2854 -0.9589 3063255 Maybridge4_000378 C/C(=N\O)/c1cc(Cl)cc(Cl)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B05 compound treatment 41320.0 -253.0 -0.01 41560.0 -1740.0 -0.13 -0.1032 -0.781 3063256 Maybridge4_000379 CCN(CC)Cc1c(C)c(C)c(C)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B06 compound treatment 3720.0 -37900.0 -2.19 3360.0 -39900.0 -3.02 -3.6882 -0.9876 3178441 Maybridge4_000380 Oc1c(Cl)cc(Cl)cc1C2Nc3cc(ccc3-n4cccc24)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B07 compound treatment 28840.0 -12700.0 -0.74 27480.0 -15800.0 -1.2 -1.3681 -0.9729 1227211 Maybridge4_000381 CCC(C)(C)NC(=S)Nc1cccc(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B08 compound treatment 36200.0 -5370.0 -0.31 38400.0 -4900.0 -0.37 -0.4821 -0.9962 3178442 Maybridge4_000382 Cc1c(C)c(C)c2[nH]c(SCc3nc(no3)c4ccc(Cl)cc4)nc2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B09 compound treatment 2760.0 -38800.0 -2.25 3440.0 -39900.0 -3.02 -3.7233 -0.9895 3063257 Maybridge4_000383 CSC1=C(C#N)C(=O)NC(S1)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B10 compound treatment 37120.0 -4450.0 -0.26 41000.0 -2300.0 -0.17 -0.3052 -0.9815 3178443 Maybridge4_000384 C/C(=N\Cc1ccccc1)/c2c(C)cc(C)cc2O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B11 compound treatment 19400.0 -22200.0 -1.28 19240.0 -24100.0 -1.82 -2.1959 -0.9854 1417340 Maybridge4_000385 COc1cc(cc(OC)c1OC)C2Nc3ccccc3S2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B12 compound treatment 39320.0 -2250.0 -0.13 36640.0 -6660.0 -0.5 -0.4485 -0.8618 1464378 Maybridge4_000386 N#CC1CN(CCc2ccccc2)CN(CCc3ccccc3)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B13 compound treatment 39480.0 -2090.0 -0.12 45000.0 1710.0 0.13 0.0055 0.0312 1213608 Maybridge4_000387 COc1cc(CO)c(CC(=O)NN)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B14 compound treatment 42640.0 1070.0 0.06 52800.0 9510.0 0.72 0.5525 0.7651 1103050 Maybridge4_000388 CC1(C)OC(=O)C(=Cc2ccc[nH]2)C(=O)O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B15 compound treatment 19360.0 -22200.0 -1.29 24360.0 -18900.0 -1.43 -1.9235 -0.9986 1559616 Maybridge4_000389 COc1cc(OC)cc(c1)c2nc(N)c3c(C)c(sc3n2)c4ccc(OC)c(OC)c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B16 compound treatment 34880.0 -6690.0 -0.39 40040.0 -3260.0 -0.25 -0.4484 -0.976 1513039 Maybridge4_000390 Cc1onc(c1NC(=O)N2CCCC2=O)c3c(Cl)cccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B17 compound treatment 35280.0 -6290.0 -0.36 49400.0 6110.0 0.46 0.069 0.1172 1918178 Maybridge4_000391 Cc1ccc(NC(=O)C2C(C3CC2C=C3)C(=O)O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B18 compound treatment 40240.0 -1330.0 -0.08 43400.0 105.0 0.01 -0.049 -0.631 3178444 Maybridge4_000392 CS/C(=N\c1ccccc1C(F)(F)F)/N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B19 compound treatment 39360.0 -2210.0 -0.13 48720.0 5430.0 0.41 0.1997 0.4643 3178445 Maybridge4_000393 CCOC(=O)c1nc2ccccc2c(=O)n1/N=C/c3cc(Cl)cc(Cl)c3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B20 compound treatment 17400.0 -24200.0 -1.4 21600.0 -21700.0 -1.64 -2.1515 -0.9969 3063259 Maybridge4_000394 Cc1c(C)c(C)c(c(C)c1C)S(=O)(=O)N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B21 compound treatment 38880.0 -2690.0 -0.16 41360.0 -1940.0 -0.15 -0.2139 -0.9995 3063260 Maybridge4_000395 CSC(=NS(=O)(=O)c1ccccc1)SC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B22 compound treatment 28720.0 -12900.0 -0.74 33480.0 -9820.0 -0.74 -1.0519 -1.0 1232359 Maybridge4_000396 Cc1onc(c1C(=O)ON2C(=O)CCC2=O)c3c(Cl)cccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B23 mock treatment 55520.0 13900.0 0.81 52240.0 8950.0 0.68 1.0502 0.9961 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 B24 mock treatment 49560.0 7990.0 0.46 47600.0 4310.0 0.33 0.5577 0.9853 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C01 compound treatment 45600.0 4030.0 0.23 48440.0 5150.0 0.39 0.4404 0.97 3063261 Maybridge4_000397 CN(C(=O)COc1cc(n(C)n1)C(F)(F)F)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C02 compound treatment 27600.0 -14000.0 -0.81 34800.0 -8500.0 -0.64 -1.0271 -0.9935 1015362 Maybridge4_000398 CCOC(=O)c1cccc2C(=O)c3ccccc3-c21 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C03 compound treatment 28600.0 -13000.0 -0.75 25080.0 -18200.0 -1.38 -1.5064 -0.9593 1410184 Maybridge4_000399 Cc1ccc(Oc2ncccc2NC(=O)c3ccc(Cl)cc3Cl)c4CCCc41 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C04 compound treatment 43600.0 2030.0 0.12 46960.0 3670.0 0.28 0.2792 0.9269 1430911 Maybridge4_000400 OC(=O)CCC(=O)c1ccc2OCCCOc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C05 compound treatment 40120.0 -1450.0 -0.08 42800.0 -495.0 -0.04 -0.086 -0.9336 3063262 Maybridge4_000401 COc1cc(OC)nc(N/C=N/O)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C06 compound treatment 36960.0 -4610.0 -0.27 46440.0 3150.0 0.24 -0.0206 -0.0576 1594886 Maybridge4_000402 Cn1c(=O)cc(Nc2ccccc2)c3c(=O)n(c4ccccc4)c(=O)n(c5ccccc5)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C07 compound treatment 41200.0 -373.0 -0.02 47600.0 4310.0 0.33 0.2152 0.6588 3063263 Maybridge4_000403 OC(=O)c1cc(=O)c2c(O)cccc2o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C08 compound treatment 25480.0 -16100.0 -0.93 27680.0 -15600.0 -1.18 -1.4951 -0.9931 3063264 Maybridge4_000404 CC(C)NC(=O)Oc1cccc(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C09 compound treatment 41400.0 -173.0 -0.01 43960.0 665.0 0.05 0.0285 0.5559 3178446 Maybridge4_000405 COC(=O)c1ccc(cc1)C(=O)NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C10 compound treatment 33320.0 -8250.0 -0.48 43400.0 105.0 0.01 -0.3325 -0.6953 1676301 Maybridge4_000406 COC(=O)C1C(NC(C(C(=O)OC)S1(=O)=O)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C11 compound treatment 43520.0 1950.0 0.11 48720.0 5430.0 0.41 0.3702 0.8692 3063265 Maybridge4_000407 O=C1CC(=NN1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C12 compound treatment 6720.0 -34900.0 -2.02 9480.0 -33800.0 -2.56 -3.2378 -0.9931 1343081 Maybridge4_000408 CC(C1CC1)N(C(=O)c2cc(C)c(Cl)cc2Cl)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C13 compound treatment 27480.0 -14100.0 -0.82 30040.0 -13300.0 -1.0 -1.2868 -0.9948 1138226 Maybridge4_000409 COc1ccc2c(c1)nnc3n[nH]c(=O)n32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C14 compound treatment 40800.0 -773.0 -0.04 48840.0 5550.0 0.42 0.2651 0.6281 1419670 Maybridge4_000410 OC(=O)CNC(=O)CSc1ccc(Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C15 compound treatment 36680.0 -4890.0 -0.28 38880.0 -4420.0 -0.33 -0.4367 -0.9966 3063266 Maybridge4_000411 CC1=C(C#N)C(C(=C(C)N1)C#N)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C16 compound treatment 21600.0 -20000.0 -1.16 19880.0 -23400.0 -1.77 -2.0715 -0.9787 3178530 Maybridge4_000412 CCC1(CCCCN(C)C1=O)c2cccc(OC(=O)Nc3ccc(OC(F)(F)F)cc3)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C17 compound treatment 26080.0 -15500.0 -0.9 33960.0 -9340.0 -0.71 -1.1343 -0.993 1346230 Maybridge4_000413 N#Cc1cccc2cccc(Sc3ccccc3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C18 compound treatment 27240.0 -14300.0 -0.83 31520.0 -11800.0 -0.89 -1.2174 -0.9994 1555561 Maybridge4_000414 COc1ccc(OC)c(CCCc2cc(OC)ccc2OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C19 compound treatment 40160.0 -1410.0 -0.08 44440.0 1150.0 0.09 0.0034 0.0287 3063267 Maybridge4_000415 CCN(CC)C(=O)Nc1ccc(OC)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C20 compound treatment 35360.0 -6210.0 -0.36 41080.0 -2220.0 -0.17 -0.3731 -0.9396 1920088 Maybridge4_000416 S=c1nc(c2ccco2)n(Cc3ccccc3)c(=S)n1/C(=N/Cc4ccccc4)/c5ccco5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C21 compound treatment 43520.0 1950.0 0.11 47200.0 3910.0 0.3 0.2888 0.9128 3178531 Maybridge4_000417 FC(F)(F)c1cccc(c1)c2nc3ccccn3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C22 compound treatment 43720.0 2150.0 0.12 48640.0 5350.0 0.4 0.3741 0.8837 3178532 Maybridge4_000418 O=C(/C=C\1/NN=C(NC1=O)c2ccccc2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C23 mock treatment 42560.0 988.0 0.06 46560.0 3270.0 0.25 0.2152 0.8484 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 C24 mock treatment 44760.0 3190.0 0.18 48280.0 4990.0 0.38 0.3974 0.946 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D01 compound treatment 43320.0 1750.0 0.1 43320.0 25.0 0.0 0.0729 0.7202 3178533 Maybridge4_000419 CC1(C)C2(C)CCC1(OC2=O)C(=O)N3NC(=O)[C@H]([C@@H]3c4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D02 compound treatment 41520.0 -52.5 0.0 43040.0 -255.0 -0.02 -0.0158 -0.8086 3063268 Maybridge4_000420 FC(F)(F)c1cc(c(Br)c(c1Br)n2cccc2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D03 compound treatment 37000.0 -4570.0 -0.26 40720.0 -2580.0 -0.19 -0.3252 -0.9886 1316662 Maybridge4_000421 Clc1ccc(NC(=S)NC(Cn2ccnc2)c3ccccc3)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D04 compound treatment 29640.0 -11900.0 -0.69 31520.0 -11800.0 -0.89 -1.1191 -0.9921 1725083 Maybridge4_000422 Cc1c(N)c2c(cc1N3CCCC3)C(C)(C)CC2(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D05 compound treatment 20480.0 -21100.0 -1.22 26960.0 -16300.0 -1.24 -1.7384 -1.0 1718122 Maybridge4_000423 C1c2sc(Nc3ccccc3)nc2-c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D06 compound treatment 41320.0 -253.0 -0.01 48160.0 4870.0 0.37 0.25 0.6785 3178534 Maybridge4_000424 FC(F)(F)c1cc(cc(c1)S(=O)(=O)N=C2NCCCN2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D07 compound treatment 37760.0 -3810.0 -0.22 47000.0 3710.0 0.28 0.0421 0.118 1138900 Maybridge4_000425 CC(C)(C)NC(=O)NCc1ccncc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D08 compound treatment 39480.0 -2090.0 -0.12 42160.0 -1140.0 -0.09 -0.1465 -0.9858 3178535 Maybridge4_000426 FC(F)(F)c1cc(NCN2C(=O)CCC2=O)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D09 compound treatment 40680.0 -893.0 -0.05 43440.0 145.0 0.01 -0.0288 -0.5449 3178536 Maybridge4_000427 COc1cccc(NC2=C(C#N)C(=O)NC(S2)c3cccc(OC)c3O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D10 compound treatment 37560.0 -4010.0 -0.23 37000.0 -6300.0 -0.48 -0.5013 -0.9456 3063269 Maybridge4_000428 Clc1ccc(cc1)S(=O)(=O)CS(=O)(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D11 compound treatment 28720.0 -12900.0 -0.74 31680.0 -11600.0 -0.88 -1.1482 -0.9966 1023491 Maybridge4_000429 Oc1ccc(Br)cc1C2Nc3ccccc3S2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D12 compound treatment 38600.0 -2970.0 -0.17 46400.0 3110.0 0.24 0.0444 0.1524 3178537 Maybridge4_000430 C/C(=N\O)/c1nnn(c1C)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D13 compound treatment 43560.0 1990.0 0.12 48640.0 5350.0 0.4 0.3675 0.8737 1381610 Maybridge4_000431 CC1(C)C2CCC(C2)C1(C)NC(=S)NCC3CCCO3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D14 compound treatment 36640.0 -4930.0 -0.29 40920.0 -2380.0 -0.18 -0.3292 -0.975 3178538 Maybridge4_000432 FC(F)(F)c1cccc(CS(=O)(=O)Cc2cccc(c2)C(F)(F)F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D15 compound treatment 23480.0 -18100.0 -1.05 31840.0 -11500.0 -0.87 -1.3543 -0.9956 1650135 Maybridge4_000433 Cc1c(C)c(C)c(C(=O)c2ccccc2C(=O)NCc3cccnc3)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D16 compound treatment 36640.0 -4930.0 -0.29 45120.0 1830.0 0.14 -0.1044 -0.3289 1002759 Maybridge4_000434 OC(C(O)C(O)c1nc2ccccc2[nH]1)C(O)c3nc4ccccc4[nH]3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D17 compound treatment 21080.0 -20500.0 -1.19 27080.0 -16200.0 -1.23 -1.7074 -0.9999 1658002 Maybridge4_000435 Cc1c(C)c(C)c(CSC2CC(=O)N(C2=O)c3ccccc3)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D18 compound treatment 32600.0 -8970.0 -0.52 33920.0 -9380.0 -0.71 -0.8694 -0.9883 3062531 Maybridge4_000436 Clc1ccc(cc1Cl)S(=O)(=O)NC(=N)c2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D19 compound treatment 36000.0 -5570.0 -0.32 38240.0 -5060.0 -0.38 -0.4989 -0.9964 2117992 Maybridge4_000437 COc1cccc(/C=N/O)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D20 compound treatment 32320.0 -9250.0 -0.54 30520.0 -12800.0 -0.97 -1.0628 -0.9613 1204180 Maybridge4_000438 Clc1ccc(cc1Cl)S(=O)(=O)NCCc2c[nH]c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D21 compound treatment 39760.0 -1810.0 -0.11 38200.0 -5100.0 -0.39 -0.347 -0.868 3062533 Maybridge4_000439 CS/C(=N\S(=O)(=O)c1ccccc1)/N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D22 compound treatment 37640.0 -3930.0 -0.23 39520.0 -3780.0 -0.29 -0.3632 -0.9937 1417838 Maybridge4_000440 COC(=O)CC1(Oc2ccc(Br)cc2C(=O)N1c3ccc(F)cc3F)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D23 mock treatment 47960.0 6390.0 0.37 51000.0 7710.0 0.58 0.6741 0.9759 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 D24 mock treatment 39760.0 -1810.0 -0.11 46880.0 3590.0 0.27 0.1176 0.4043 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E01 compound treatment 41560.0 -12.5 0.0 45920.0 2630.0 0.2 0.14 0.7045 3062534 Maybridge4_000441 Cn1nc(OC(C)(C)C(=O)Oc2ccc(Cl)cc2Cl)cc1C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E02 compound treatment 38520.0 -3050.0 -0.18 45680.0 2390.0 0.18 0.0026 0.0103 1024184 Maybridge4_000442 CCC(=O)c1ccc(OC)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E03 compound treatment 26880.0 -14700.0 -0.85 33440.0 -9860.0 -0.75 -1.1294 -0.9978 1519339 Maybridge4_000443 Cc1ccc(Oc2ncccc2NC(=O)CSc3ccccn3)c4CCCc41 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E04 compound treatment 41520.0 -52.5 0.0 45000.0 1710.0 0.13 0.0891 0.6902 3062535 Maybridge4_000444 Cc1cc(=O)n(CCO)c(=O)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E05 compound treatment 42480.0 908.0 0.05 45320.0 2030.0 0.15 0.1456 0.8983 3178539 Maybridge4_000445 OC(=O)CC(C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C2=CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E06 compound treatment 22640.0 -18900.0 -1.1 29880.0 -13400.0 -1.02 -1.4937 -0.9993 1643916 Maybridge4_000446 O=C(N1CCCCC1)c2cccc3Cc4ccccc4-c32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E07 compound treatment 41120.0 -453.0 -0.03 47280.0 3990.0 0.3 0.1948 0.6432 3178540 Maybridge4_000447 OC(=O)c1oc(C(=O)O)c(OCc2ccccc2)c1OCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E08 compound treatment 36400.0 -5170.0 -0.3 43360.0 65.0 0.0 -0.2084 -0.6954 3062536 Maybridge4_000448 O=C(Oc1ccccc1)N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E09 compound treatment 40640.0 -933.0 -0.05 41160.0 -2140.0 -0.16 -0.1525 -0.8948 1039079 Maybridge4_000449 OC(=O)c1cccc(Cl)c1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E10 compound treatment 39680.0 -1890.0 -0.11 46640.0 3350.0 0.25 0.1015 0.3679 1423015 Maybridge4_000450 CC(=O)N[C@@H](Cc1ccccc1)C(=O)NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E11 compound treatment 36840.0 -4730.0 -0.27 43320.0 25.0 0.0 -0.1925 -0.7022 3178542 Maybridge4_000451 OC(Cn1ccccc1=N)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E12 compound treatment 28480.0 -13100.0 -0.76 31920.0 -11400.0 -0.86 -1.1452 -0.998 3062537 Maybridge4_000452 CC(C1CC1)N(C(=O)C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E13 compound treatment 34360.0 -7210.0 -0.42 42920.0 -375.0 -0.03 -0.3156 -0.7534 1704451 Maybridge4_000453 CN(C)C(=O)c1cccc2C(=O)c3ccccc3-c21 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E14 compound treatment 38040.0 -3530.0 -0.2 47160.0 3870.0 0.29 0.0622 0.1741 3178543 Maybridge4_000454 CC(C)(C)C(=O)Nc1ccn([C@H]2C[C@H](O)[C@@H](COC(=O)C(C)(C)C)O2)c(=O)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E15 compound treatment 33200.0 -8370.0 -0.49 37480.0 -5820.0 -0.44 -0.6542 -0.9988 3062540 Maybridge4_000455 COc1ccc2c(OC)ccc3C(=O)C=Cc1c32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E16 compound treatment 35120.0 -6450.0 -0.37 44400.0 1110.0 0.08 -0.2052 -0.5357 1289531 Maybridge4_000456 Clc1ccc(cc1)C(=O)OC2CN3CCC2CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E17 compound treatment 36000.0 -5570.0 -0.32 41520.0 -1780.0 -0.13 -0.3233 -0.9245 1672892 Maybridge4_000457 CNC(=O)c1ccccc1S(=O)c2cccc3cccc(C(=O)O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E18 compound treatment 29680.0 -11900.0 -0.69 32440.0 -10900.0 -0.82 -1.0682 -0.9962 3062541 Maybridge4_000458 COc1ccc(OC)c(CCCCc2cc(OC)ccc2OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E19 compound treatment 4320.0 -37300.0 -2.16 6000.0 -37300.0 -2.82 -3.5223 -0.9912 3178544 Maybridge4_000459 Clc1ccc(S/C=C/C(=O)c2ccccc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E20 compound treatment 29880.0 -11700.0 -0.68 36320.0 -6980.0 -0.53 -0.8523 -0.9924 3062542 Maybridge4_000460 C/C(=N\O)/C1(CC2(C)CC3(C)CC(C)(C2)C1)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E21 compound treatment 38680.0 -2890.0 -0.17 44640.0 1350.0 0.1 -0.0465 -0.2372 3178545 Maybridge4_000461 CC(=O)OC[C@H]1O[C@@H](Nc2ccc(C)cc2)[C@H](OC(=O)C)[C@@H](OC(=O)C)[C@@H]1OC(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E22 compound treatment 41960.0 388.0 0.02 47000.0 3710.0 0.28 0.2142 0.7613 3062543 Maybridge4_000462 CC1(C)N(O)C(NC1=S)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E23 mock treatment 46200.0 4630.0 0.27 50240.0 6950.0 0.53 0.5613 0.9512 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 E24 mock treatment 43120.0 1550.0 0.09 41520.0 -1780.0 -0.13 -0.0316 -0.1957 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F01 compound treatment 40240.0 -1330.0 -0.08 41280.0 -2020.0 -0.15 -0.1624 -0.9502 3178546 Maybridge4_000463 Fc1ccc2CC(=O)C(Cc2c1)C3=Cc4ccc(F)cc4CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F02 compound treatment 39040.0 -2530.0 -0.15 38960.0 -4340.0 -0.33 -0.3358 -0.9342 1526672 Maybridge4_000464 COc1ccc(CCNC(=O)c2nc3ccccc3c(=O)n2n4cccc4)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F03 compound treatment 47520.0 5950.0 0.34 44680.0 1390.0 0.1 0.3178 0.8823 3062544 Maybridge4_000465 CC(OC(=O)c1cccc(Cl)c1)c2ccc[n+](C)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F04 compound treatment 39960.0 -1610.0 -0.09 42920.0 -375.0 -0.03 -0.0861 -0.8821 1352177 Maybridge4_000466 CSc1cccc(NC(=S)Nc2cc3c(c(N)c2C)C(C)(C)CC3(C)C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F05 compound treatment 37920.0 -3650.0 -0.21 44960.0 1670.0 0.13 -0.0605 -0.2457 3062545 Maybridge4_000467 CC(C=C1C(=O)NC(=O)NC1=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F06 compound treatment 36200.0 -5370.0 -0.31 48280.0 4990.0 0.38 0.0467 0.0955 3062546 Maybridge4_000468 SC1=NC2(CCCC2)NN1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F07 compound treatment 36200.0 -5370.0 -0.31 43000.0 -295.0 -0.02 -0.2359 -0.7559 3178547 Maybridge4_000469 C(c1ccc(/N=C/c2ccccn2)cc1)c3ccc(/N=C/c4ccccn4)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F08 compound treatment 41280.0 -293.0 -0.02 46960.0 3670.0 0.28 0.1842 0.6627 1528873 Maybridge4_000470 O=C1CCC(=O)N1CNc2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F09 compound treatment 35520.0 -6050.0 -0.35 44440.0 1150.0 0.09 -0.1867 -0.5168 1318293 Maybridge4_000471 CC(C)(C)C(=O)Nc1ccccc1C(=O)NCc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F10 compound treatment 10400.0 -31200.0 -1.81 10800.0 -32500.0 -2.46 -3.0163 -0.9885 3178548 Maybridge4_000472 Clc1ccc(SCc2ccc(NC(=O)Nc3cccc(Cl)c3)o2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F11 compound treatment 19680.0 -21900.0 -1.27 29400.0 -13900.0 -1.05 -1.6406 -0.9957 3062547 Maybridge4_000473 NC(=N)Nc1nc(cs1)c2ccc(cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F12 compound treatment 20320.0 -21300.0 -1.23 24200.0 -19100.0 -1.45 -1.8927 -0.9968 3178625 Maybridge4_000474 CS/C(=C(/C#N)\C(=O)c1cccs1)/Nc2cccc(Cl)c2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F13 compound treatment 36720.0 -4850.0 -0.28 37920.0 -5380.0 -0.41 -0.4865 -0.9837 3178626 Maybridge4_000475 OC(Cc1ccccc1)(c2ccccc2)c3ccccc3NC(=S)NC4CC5CC4C=C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F14 compound treatment 34520.0 -7050.0 -0.41 41000.0 -2300.0 -0.17 -0.4118 -0.9274 3062548 Maybridge4_000476 Cc1nnsc1C(=O)Nc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F15 compound treatment 29720.0 -11900.0 -0.69 32640.0 -10700.0 -0.81 -1.0559 -0.9968 1004988 Maybridge4_000477 ON=C(Cc1ccccc1)Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F16 compound treatment 32200.0 -9370.0 -0.54 38920.0 -4380.0 -0.33 -0.6181 -0.9719 3178627 Maybridge4_000478 Cc1onc(c1C(=O)NC(=S)N2CCOCC2)c3c(Cl)cccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F17 compound treatment 23560.0 -18000.0 -1.04 29560.0 -13700.0 -1.04 -1.4731 -1.0 3062549 Maybridge4_000479 NC(=O)Nc1ccc(cc1)/C(=C/c2ccncc2)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F18 compound treatment 24000.0 -17600.0 -1.02 26160.0 -17100.0 -1.3 -1.637 -0.9928 3062550 Maybridge4_000480 CN(C)C(=S)SCc1c(C)c(C)c(C)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F19 compound treatment 30400.0 -11200.0 -0.65 41040.0 -2260.0 -0.17 -0.5784 -0.864 3178628 Maybridge4_000481 COc1ccc(cc1)n2c(CC#N)nnc2SCc3c(C)c(C)c(C)c(C)c3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F20 compound treatment 30560.0 -11000.0 -0.64 36840.0 -6460.0 -0.49 -0.7967 -0.9913 3178629 Maybridge4_000482 CC1(C)ON(C(=N1)NC(=O)NC(=O)c2ccccc2Cl)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F21 compound treatment 36200.0 -5370.0 -0.31 44560.0 1270.0 0.1 -0.1524 -0.4679 3062551 Maybridge4_000483 O=S(=O)(/N=C/1\NCC2CCCC2N1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F22 compound treatment 39920.0 -1650.0 -0.1 41960.0 -1340.0 -0.1 -0.1392 -0.9996 3178630 Maybridge4_000484 CC(CO)(CO)NC(=S)Nc1ccc(F)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F23 mock treatment 42960.0 1390.0 0.08 44880.0 1590.0 0.12 0.1417 0.981 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 F24 mock treatment 42440.0 868.0 0.05 41880.0 -1420.0 -0.11 -0.0402 -0.3397 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G01 compound treatment 47760.0 6190.0 0.36 47720.0 4430.0 0.33 0.4903 0.9994 1441207 Maybridge4_000485 CC(C)(C)c1cc2[nH]c(=N)[nH]c(=N)n2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G02 compound treatment 24680.0 -16900.0 -0.98 30320.0 -13000.0 -0.98 -1.3865 -1.0 1390371 Maybridge4_000486 O=c1c(Cc2ccccc2OCc3ccccc3)coc4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G03 compound treatment 37160.0 -4410.0 -0.26 41840.0 -1460.0 -0.11 -0.2586 -0.9292 3062552 Maybridge4_000487 COc1ccccc1C2OC(=O)C[C@H]2C(=O)NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G04 compound treatment 31840.0 -9730.0 -0.56 32720.0 -10600.0 -0.8 -0.9647 -0.9853 1630105 Maybridge4_000488 Brc1ccc(cc1)C(=O)c2cc3OCCCOc3cc2Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G05 compound treatment 38760.0 -2810.0 -0.16 41200.0 -2100.0 -0.16 -0.2274 -0.9999 1255736 Maybridge4_000489 COc1cc(OC)nc(NCC(NC(=O)c2ccccc2)C(=O)N)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G06 compound treatment 32360.0 -9210.0 -0.53 37680.0 -5620.0 -0.43 -0.678 -0.9936 1191076 Maybridge4_000490 CNc1cc(=O)n(c2ccccc2)c(=O)n1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G07 compound treatment 33360.0 -8210.0 -0.48 40560.0 -2740.0 -0.21 -0.4828 -0.9305 1024944 Maybridge4_000491 CCOC(=O)c1oc(C(=O)OCC)c(O)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G08 compound treatment 13240.0 -28300.0 -1.64 16880.0 -26400.0 -2.0 -2.5746 -0.9952 3062592 Maybridge4_000492 CC(C)(C)c1ccc2cc(C#N)c(C#N)cc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G09 compound treatment 26040.0 -15500.0 -0.9 33640.0 -9660.0 -0.73 -1.1531 -0.9947 3062593 Maybridge4_000493 O=C1N(CCCCN2C(=O)c3ccccc3S2(=O)=O)S(=O)(=O)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G10 compound treatment 27120.0 -14500.0 -0.84 35240.0 -8060.0 -0.61 -1.0232 -0.9879 3062594 Maybridge4_000494 Cc1ccc(NC(=O)N(C2=NCC(C)(C)S2)c3ccc(F)c(Cl)c3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G11 compound treatment 29720.0 -11900.0 -0.69 38440.0 -4860.0 -0.37 -0.7454 -0.9571 1051499 Maybridge4_000495 CC(O)c1ccc2ccccc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G12 compound treatment 25480.0 -16100.0 -0.93 30800.0 -12500.0 -0.95 -1.3281 -1.0 1332464 Maybridge4_000496 OCCOC(=O)c1cccc2C(=O)c3ccccc3-c21 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G13 compound treatment 15880.0 -25700.0 -1.49 22080.0 -21200.0 -1.61 -2.1881 -0.9993 1397918 Maybridge4_000497 CCCN(CCC)C(=O)c1cccc2C(=O)c3ccccc3-c21 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G14 compound treatment 36840.0 -4730.0 -0.27 42560.0 -735.0 -0.06 -0.2332 -0.8336 3178631 Maybridge4_000498 CC(C)(C)C(=O)OC[C@H]1O[C@H](C[C@@H]1OC(=O)C(C)(C)C)n2cnc3c(N)ncnc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G15 compound treatment 29600.0 -12000.0 -0.69 32200.0 -11100.0 -0.84 -1.0843 -0.9955 3062595 Maybridge4_000499 O=C(OC1=CC(=O)c2cccc3cccc1c23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G16 compound treatment 15000.0 -26600.0 -1.54 14800.0 -28500.0 -2.16 -2.6138 -0.9863 1645132 Maybridge4_000500 O=C(NC1CCN(Cc2cccc3ccccc23)CC1)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G17 compound treatment 33920.0 -7650.0 -0.44 38680.0 -4620.0 -0.35 -0.5605 -0.993 1430296 Maybridge4_000501 OCc1cccc2cccc(S(=O)c3cccc4cccc(C(=O)O)c34)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G18 compound treatment 23640.0 -17900.0 -1.04 29640.0 -13700.0 -1.03 -1.4655 -1.0 1284168 Maybridge4_000502 Brc1ccc(Cc2csc3ccccc3c2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G19 compound treatment 24800.0 -16800.0 -0.97 30520.0 -12800.0 -0.97 -1.3709 -1.0 3178632 Maybridge4_000503 FC(F)(F)Oc1ccccc1NC(=O)CC(=O)Nc2ccccc2OC(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G20 compound treatment 35720.0 -5850.0 -0.34 38960.0 -4340.0 -0.33 -0.4718 -0.9999 1186920 Maybridge4_000504 NNC(=O)C1(CCCC2CCC1)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G21 compound treatment 26640.0 -14900.0 -0.87 33280.0 -10000.0 -0.76 -1.1478 -0.9978 3062596 Maybridge4_000505 FC1(C(=O)Nc2c(Cl)c(Cl)ccc2C1=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G22 compound treatment 38240.0 -3330.0 -0.19 41200.0 -2100.0 -0.16 -0.2487 -0.9952 3178633 Maybridge4_000506 CC(C)(C)OC(=O)Cn1ccc(=O)[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G23 mock treatment 39800.0 -1770.0 -0.1 42720.0 -575.0 -0.04 -0.1034 -0.927 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 G24 mock treatment 38360.0 -3210.0 -0.19 45480.0 2190.0 0.17 -0.0147 -0.0589 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H01 compound treatment 42000.0 428.0 0.02 38640.0 -4660.0 -0.35 -0.2316 -0.6558 3178634 Maybridge4_000507 O/N=C(/C1CC2CCC1CC2)\c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H02 compound treatment 25160.0 -16400.0 -0.95 26880.0 -16400.0 -1.24 -1.551 -0.9913 1138209 Maybridge4_000508 N1C(c2cccn2-c3ccccc13)c4cccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H03 compound treatment 26600.0 -15000.0 -0.87 29360.0 -13900.0 -1.05 -1.3593 -0.9953 1326325 Maybridge4_000509 Cc1c(C)c(C)c(CN2C(=O)c3ccccc3C2=O)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H04 compound treatment 36280.0 -5290.0 -0.31 42880.0 -415.0 -0.03 -0.239 -0.7755 3062597 Maybridge4_000510 Cc1c(cc2c(c1n3cccc3)C(C)(C)CC2(C)C)N4CCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H05 compound treatment 31160.0 -10400.0 -0.6 37680.0 -5620.0 -0.43 -0.7271 -0.9853 3178635 Maybridge4_000511 Fc1ccc(cc1)C(=O)CSc2nsc(SCC(=O)c3ccc(F)cc3)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H06 compound treatment 1480.0 -40100.0 -2.32 2040.0 -41300.0 -3.12 -3.8506 -0.9894 3178636 Maybridge4_000512 CC(C)C1CCC(C)CC1NC(=S)Nc2cccc(F)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H07 compound treatment 15960.0 -25600.0 -1.48 23280.0 -20000.0 -1.52 -2.1206 -0.9999 1248377 Maybridge4_000513 CC1CCCCN1C(=S)Nc2ccc(cc2)S(=O)(=O)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H08 compound treatment 26920.0 -14700.0 -0.85 28760.0 -14500.0 -1.1 -1.3783 -0.9918 3178637 Maybridge4_000514 COc1cccc(OC)c1C(=O)Nc2cc(c(Cl)cc2OC)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H09 compound treatment 31880.0 -9690.0 -0.56 40200.0 -3100.0 -0.23 -0.5627 -0.9248 1054040 Maybridge4_000515 CC(C)C1=NNC(=O)C1(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H10 compound treatment 22520.0 -19100.0 -1.1 27040.0 -16300.0 -1.23 -1.6506 -0.9985 1253333 Maybridge4_000516 Nc1nc2c(nnn2c3ccccc13)C(=O)N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H11 compound treatment 20360.0 -21200.0 -1.23 27920.0 -15400.0 -1.16 -1.692 -0.9996 1700266 Maybridge4_000517 COc1ccc(CCNC(=S)NCCc2ccccc2)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H12 compound treatment 31120.0 -10500.0 -0.61 36160.0 -7140.0 -0.54 -0.8101 -0.9984 3178638 Maybridge4_000518 O/N=C(\C#N)/C(=O)c1ccco1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H13 compound treatment 35560.0 -6010.0 -0.35 38520.0 -4780.0 -0.36 -0.5019 -0.9998 1672819 Maybridge4_000519 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H14 compound treatment 29680.0 -11900.0 -0.69 39240.0 -4060.0 -0.31 -0.7043 -0.9337 3178639 Maybridge4_000520 Fc1cc(F)c(NC(=S)N2CCOCC2)c(F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H15 compound treatment 26000.0 -15600.0 -0.9 32720.0 -10600.0 -0.8 -1.204 -0.9982 1546700 Maybridge4_000521 Cc1c(C)c(C)c(C(=O)c2ccccc2C(=O)NN)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H16 compound treatment 26800.0 -14800.0 -0.86 28600.0 -14700.0 -1.11 -1.3917 -0.9916 3062598 Maybridge4_000522 Fc1cccc(NCc2cccs2)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H17 compound treatment 32640.0 -8930.0 -0.52 38600.0 -4700.0 -0.36 -0.6172 -0.9832 3178640 Maybridge4_000523 NC(=O)Nc1ccc(cc1)/C(=C/c2ccc(Cl)c(Cl)c2)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H18 compound treatment 26560.0 -15000.0 -0.87 33360.0 -9940.0 -0.75 -1.1468 -0.9974 3062599 Maybridge4_000524 CN(C)C(=S)SCC(=O)c1ccc(Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H19 compound treatment 9040.0 -32500.0 -1.88 18760.0 -24500.0 -1.86 -2.646 -1.0 1221296 Maybridge4_000525 Cc1cc(C)c2-c3[nH]c(nc3C(C)(C)Cc2c1)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H20 compound treatment 24600.0 -17000.0 -0.98 27000.0 -16300.0 -1.23 -1.5675 -0.9937 1556252 Maybridge4_000526 Cc1c(C)c(C)c(c(C)c1C)S(=O)(=O)NC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H21 compound treatment 38360.0 -3210.0 -0.19 45040.0 1750.0 0.13 -0.0382 -0.1674 3062600 Maybridge4_000527 CC1CN/C(=N/S(=O)(=O)c2ccccc2)/N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H22 compound treatment 38320.0 -3250.0 -0.19 43240.0 -55.0 0.0 -0.1362 -0.7226 1621149 Maybridge4_000528 CC1CC(C)CN(C1)c2ccc(NS(=O)(=O)c3ccccc3)cc2C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H23 mock treatment 43160.0 1590.0 0.09 47480.0 4190.0 0.32 0.289 0.8762 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 H24 mock treatment 38200.0 -3370.0 -0.2 41640.0 -1660.0 -0.13 -0.2267 -0.9769 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I01 compound treatment 24080.0 -17500.0 -1.01 32040.0 -11300.0 -0.85 -1.319 -0.9963 3062601 Maybridge4_000529 Cc1ccc(Oc2ncc(cc2Cl)C(F)(F)F)c3CCCc31 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I02 compound treatment 37400.0 -4170.0 -0.24 44400.0 1110.0 0.08 -0.1118 -0.437 3178641 Maybridge4_000530 CCOC(=O)CSc1nnc(S)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I03 compound treatment 32120.0 -9450.0 -0.55 37520.0 -5780.0 -0.44 -0.6964 -0.9938 3178642 Maybridge4_000531 Cc1nc(cs1)c2cc(C#N)c(SCCNS(=O)(=O)c3ccc(cc3)C(C)(C)C)nc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I04 compound treatment 34160.0 -7410.0 -0.43 45280.0 1990.0 0.15 -0.1974 -0.4339 1202864 Maybridge4_000532 Cc1ccc(cc1)C(=O)C2C(=O)N(C(=O)N(C2=O)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I05 compound treatment 27040.0 -14500.0 -0.84 34640.0 -8660.0 -0.66 -1.0586 -0.9923 1219965 Maybridge4_000533 Cc1nn(nc1C(=O)ON2C(=O)C3C4OC(C=C4)C3C2=O)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I06 compound treatment 19800.0 -21800.0 -1.26 29160.0 -14100.0 -1.07 -1.6485 -0.9966 3062602 Maybridge4_000534 COc1ccc(/C=C\2/C(Oc3ccccc3C2=O)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I07 compound treatment 27240.0 -14300.0 -0.83 44960.0 1670.0 0.13 -0.4981 -0.593 1277364 Maybridge4_000535 CCOC(=O)c1c(O)c(O)c(C(=O)OCC)n1c2ccc(OC)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I08 compound treatment 31120.0 -10500.0 -0.61 38080.0 -5220.0 -0.39 -0.7073 -0.9785 1178381 Maybridge4_000536 Fc1ccc2[nH]c3CCN(Cc3c2c1)C(=O)NCC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I09 compound treatment 21080.0 -20500.0 -1.19 26600.0 -16700.0 -1.26 -1.7331 -0.9995 1497959 Maybridge4_000537 CC(C)C1CCC(C)CC1NC(=O)c2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I10 compound treatment 23720.0 -17900.0 -1.03 29360.0 -13900.0 -1.05 -1.4772 -1.0 1039563 Maybridge4_000538 Clc1ccc2oc(cc(=O)c2c1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I11 compound treatment 14640.0 -26900.0 -1.56 21000.0 -22300.0 -1.69 -2.2967 -0.9992 1035419 Maybridge4_000539 O=C(c1ccccc1)c2ccc(cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I12 compound treatment 31640.0 -9930.0 -0.58 40440.0 -2860.0 -0.22 -0.5597 -0.9106 3178724 Maybridge4_000540 Sc1nn(c2ccc(Cl)cc2)c(=S)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I13 compound treatment 17400.0 -24200.0 -1.4 22960.0 -20300.0 -1.54 -2.0787 -0.9989 1060199 Maybridge4_000541 CNC(=O)c1cccc2C(=O)c3ccccc3-c21 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I14 compound treatment 31760.0 -9810.0 -0.57 43640.0 345.0 0.03 -0.3835 -0.6739 3178725 Maybridge4_000542 NNC(=O)c1cc(n[nH]1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I15 compound treatment 14560.0 -27000.0 -1.57 21560.0 -21700.0 -1.65 -2.27 -0.9997 1005720 Maybridge4_000543 CN(C)c1ccc(Cc2ccc(cc2)N(C)C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I16 compound treatment 7200.0 -34400.0 -1.99 13280.0 -30000.0 -2.27 -3.0147 -0.9978 1587057 Maybridge4_000544 COc1ccccc1C2CCN(Cc3cccc4ccccc34)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I17 compound treatment 39120.0 -2450.0 -0.14 38960.0 -4340.0 -0.33 -0.3325 -0.9299 2075442 Maybridge4_000545 CN1[S+](c2ccccc2C(=O)O)c3cccc4cccc(C1=O)c34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I18 compound treatment 19080.0 -22500.0 -1.3 23000.0 -20300.0 -1.54 -2.0077 -0.9966 3178726 Maybridge4_000546 Nc1ccccc1SC(CC(=O)c2ccc(Br)cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I19 compound treatment 26680.0 -14900.0 -0.86 31560.0 -11700.0 -0.89 -1.2382 -0.9999 1287387 Maybridge4_000547 OCC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I20 compound treatment 40040.0 -1530.0 -0.09 40680.0 -2620.0 -0.2 -0.2027 -0.9346 1441014 Maybridge4_000548 OC(=O)C1(CCCC2(CCC1)C(=O)O)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I21 compound treatment 33360.0 -8210.0 -0.48 41880.0 -1420.0 -0.11 -0.4122 -0.8451 1343250 Maybridge4_000549 O=C1C(C2c3ccccc3Oc4ccccc24)C(=O)c5ccccc15 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I22 compound treatment 36440.0 -5130.0 -0.3 40600.0 -2700.0 -0.2 -0.3545 -0.9831 3062641 Maybridge4_000550 OC[C@H]1O[C@@H](Oc2c[nH]c3ccc(Br)c(Cl)c23)[C@H](O)[C@@H](O)[C@H]1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I23 mock treatment 42520.0 948.0 0.05 42000.0 -1300.0 -0.1 -0.0305 -0.2714 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 I24 mock treatment 37920.0 -3650.0 -0.21 43960.0 665.0 0.05 -0.114 -0.5243 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J01 compound treatment 42800.0 1230.0 0.07 46440.0 3150.0 0.24 0.2186 0.8799 3062642 Maybridge4_000551 COC(=O)C1CCC(=O)C(C1)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J02 compound treatment 26360.0 -15200.0 -0.88 31600.0 -11700.0 -0.89 -1.2492 -1.0 1601179 Maybridge4_000552 Oc1ccc2ccccc2c1C3Nc4ccccc4-n5cccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J03 compound treatment 30240.0 -11300.0 -0.66 38800.0 -4500.0 -0.34 -0.7049 -0.9532 3062643 Maybridge4_000553 Cc1c(C)c(C)c(CN2CCCCC2)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J04 compound treatment 41200.0 -373.0 -0.02 41240.0 -2060.0 -0.16 -0.1253 -0.7976 3062644 Maybridge4_000554 CC(=O)Nc1s/c(=N\c2ccc(C)c(C)c2)/n(C(=O)C)c1c3ccc4OCOc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J05 compound treatment 29520.0 -12100.0 -0.7 36760.0 -6540.0 -0.49 -0.8435 -0.9857 1342204 Maybridge4_000555 O=S(=O)(N1CCCCC1)c2ccc(NC(=S)Nc3ccc4OCOc4c3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J06 compound treatment 11880.0 -29700.0 -1.72 20200.0 -23100.0 -1.75 -2.4526 -1.0 3062645 Maybridge4_000556 Clc1ccc(Cl)c(NC(=S)NC(=N)c2ccccc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J07 compound treatment 33160.0 -8410.0 -0.49 36160.0 -7140.0 -0.54 -0.7265 -0.9987 3178727 Maybridge4_000557 Oc1c(Cl)cc(Cl)cc1/C=N/c2ccc(CC3C(=O)Nc4ccccc34)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J08 compound treatment 38000.0 -3570.0 -0.21 38280.0 -5020.0 -0.38 -0.4148 -0.9593 3178728 Maybridge4_000558 CN1CCC2(C(C1)N=NN2c3cc(cc(c3)C(F)(F)F)C(F)(F)F)N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J09 compound treatment 16760.0 -24800.0 -1.44 22800.0 -20500.0 -1.55 -2.1135 -0.9993 3062646 Maybridge4_000559 Cc1cc(C)c(C(=O)Nc2cccc(c2)C(F)(F)F)c3CC(C)(C)C(=O)c31 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J10 compound treatment 24800.0 -16800.0 -0.97 30240.0 -13100.0 -0.99 -1.3859 -1.0 1734956 Maybridge4_000560 Nc1nc2c(nnn2c3ccccc13)c4ccc(Br)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J11 compound treatment 15240.0 -26300.0 -1.53 20600.0 -22700.0 -1.72 -2.2935 -0.9982 3178729 Maybridge4_000561 Cc1c(C)c(C)c(C(O)c2ccccc2)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J12 compound treatment 34400.0 -7170.0 -0.42 39680.0 -3620.0 -0.27 -0.4873 -0.9794 3178730 Maybridge4_000562 COc1ccc(cc1)c2c(C#N)nnn2c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J13 compound treatment 33000.0 -8570.0 -0.5 41480.0 -1820.0 -0.14 -0.4483 -0.87 1646858 Maybridge4_000563 CCN1C(C(CCC1=O)C(=O)O)c2ccc(OC)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J14 compound treatment 24480.0 -17100.0 -0.99 31520.0 -11800.0 -0.89 -1.3305 -0.9986 1299644 Maybridge4_000564 Fc1cccc(NCCc2ccccn2)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J15 compound treatment 23640.0 -17900.0 -1.04 29600.0 -13700.0 -1.04 -1.4677 -1.0 3062647 Maybridge4_000565 CCOC(=S)SCc1c(C)c(C)c(C)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J16 compound treatment 36400.0 -5170.0 -0.3 37520.0 -5780.0 -0.44 -0.521 -0.983 1536926 Maybridge4_000566 O=C(CC#N)NCc1cccs1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J17 compound treatment 19240.0 -22300.0 -1.29 19560.0 -23700.0 -1.8 -2.1853 -0.987 3178731 Maybridge4_000567 Cc1onc(c1NC(=O)Nc2cccc(c2)C(F)(F)F)c3ccccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J18 compound treatment 19640.0 -21900.0 -1.27 22680.0 -20600.0 -1.56 -2.0019 -0.9948 1727398 Maybridge4_000568 CCc1cccc(C(C)C)c1NS(=O)(=O)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J19 compound treatment 37480.0 -4090.0 -0.24 35920.0 -7380.0 -0.56 -0.5624 -0.9273 3062649 Maybridge4_000569 Nn1c(nc2ccccc2c1=O)C(=O)NCc3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J20 compound treatment 31520.0 -10100.0 -0.58 28320.0 -15000.0 -1.13 -1.2134 -0.9521 3178732 Maybridge4_000570 CC1CCCCN1CCCNC(=O)Nc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J21 compound treatment 21320.0 -20300.0 -1.17 21760.0 -21500.0 -1.63 -1.9823 -0.987 3062650 Maybridge4_000571 Clc1ccc(SCc2ccc(C#N)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J22 compound treatment 41000.0 -573.0 -0.03 38960.0 -4340.0 -0.33 -0.2555 -0.7746 3178733 Maybridge4_000572 CC1CN(CC(C)O1)c2ccc(NC(=O)c3ccco3)cc2C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J23 mock treatment 36880.0 -4690.0 -0.27 38640.0 -4660.0 -0.35 -0.4414 -0.9918 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 J24 mock treatment 39440.0 -2130.0 -0.12 40240.0 -3060.0 -0.23 -0.2509 -0.9569 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K01 compound treatment 37760.0 -3810.0 -0.22 41080.0 -2220.0 -0.17 -0.2747 -0.9907 1258100 Maybridge4_000573 OC(=O)C1CC1C(=O)Nc2ccc(Oc3ccc(Cl)cc3C4CCCCC4)nc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K02 compound treatment 30680.0 -10900.0 -0.63 31600.0 -11700.0 -0.89 -1.0722 -0.9862 3062651 Maybridge4_000574 CCOC(=O)CCSc1nnc(S)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K03 compound treatment 24880.0 -16700.0 -0.97 30920.0 -12400.0 -0.94 -1.3462 -0.9999 1465836 Maybridge4_000575 Fc1ccc(COc2ccc(cc2)C(=O)CSc3ccccn3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K04 compound treatment 28440.0 -13100.0 -0.76 34400.0 -8900.0 -0.67 -1.0141 -0.9981 1182542 Maybridge4_000576 CC1(CC2(C)CC3(C)C1)CC(C2)(C3)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K05 compound treatment 12320.0 -29300.0 -1.69 18360.0 -24900.0 -1.89 -2.533 -0.9986 3178734 Maybridge4_000577 OC1CCCCCCCCCCC1CCC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K06 compound treatment 25040.0 -16500.0 -0.96 31200.0 -12100.0 -0.92 -1.3247 -0.9997 3062652 Maybridge4_000578 CC(C)CCNC(=O)Oc1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K07 compound treatment 28240.0 -13300.0 -0.77 38400.0 -4900.0 -0.37 -0.8082 -0.9434 3178735 Maybridge4_000579 COc1ccc(OC)c2c(=O)cc(oc12)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K08 compound treatment 17440.0 -24100.0 -1.4 22680.0 -20600.0 -1.56 -2.0921 -0.9985 1674875 Maybridge4_000580 COc1ccccc1C2CCN(CC2)C(=O)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K09 compound treatment 13000.0 -28600.0 -1.66 13920.0 -29400.0 -2.22 -2.7428 -0.9894 3178736 Maybridge4_000581 CC1(C)C2CCC1(C)C(C2)NC(=O)c3cccc(c3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K10 compound treatment 14760.0 -26800.0 -1.55 19600.0 -23700.0 -1.79 -2.3667 -0.9974 1672849 Maybridge4_000582 Cc1onc(c1C(=O)N2CC(C2)Oc3ccc(Cl)cc3)c4c(F)cccc4Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K11 compound treatment 23240.0 -18300.0 -1.06 23840.0 -19500.0 -1.47 -1.7924 -0.9871 3062653 Maybridge4_000583 Cc1cc(n[nH]c1=O)c2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K12 compound treatment 26920.0 -14700.0 -0.85 35520.0 -7780.0 -0.59 -1.0164 -0.984 3062654 Maybridge4_000584 Sc1nc(c2ccccc2)n(n1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K13 compound treatment 19600.0 -22000.0 -1.27 22000.0 -21300.0 -1.61 -2.04 -0.9932 1267527 Maybridge4_000585 CC(C)CCNC(=O)c1cccc2C(=O)c3ccccc3-c21 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K14 compound treatment 20520.0 -21100.0 -1.22 25600.0 -17700.0 -1.34 -1.8096 -0.9989 3062655 Maybridge4_000586 O=C1C(CCCC1c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K15 compound treatment 19240.0 -22300.0 -1.29 24360.0 -18900.0 -1.43 -1.9284 -0.9987 3178737 Maybridge4_000587 Cc1c(cnc2ccccc12)c3nnnn3c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K16 compound treatment 23840.0 -17700.0 -1.03 29240.0 -14100.0 -1.06 -1.4787 -0.9998 1175626 Maybridge4_000588 Cc1ccc(cc1)C(=O)OC2CN3CCC2CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K17 compound treatment 27840.0 -13700.0 -0.8 29280.0 -14000.0 -1.06 -1.3127 -0.9899 3178738 Maybridge4_000589 CN1[S+](c2ccccc2C1=O)c3cccc4cccc(C(=O)O)c34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K18 compound treatment 6040.0 -35500.0 -2.06 6640.0 -36700.0 -2.77 -3.4176 -0.9892 3178739 Maybridge4_000590 CC1(C)C2CCC1(C)c3nn(c(c23)C(F)(F)F)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K19 compound treatment 18880.0 -22700.0 -1.31 19600.0 -23700.0 -1.79 -2.1979 -0.9883 1361703 Maybridge4_000591 CCOC(Cn1c2ccccc2c3ccccc13)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K20 compound treatment 32440.0 -9130.0 -0.53 30760.0 -12500.0 -0.95 -1.0451 -0.962 1031191 Maybridge4_000592 OC(=O)C1C(C2CCC1C2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K21 compound treatment 29440.0 -12100.0 -0.7 32120.0 -11200.0 -0.85 -1.0952 -0.9958 1224135 Maybridge4_000593 Cn1c(nc2ccccc12)C(C#N)C(=O)c3ccccc3I 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K22 compound treatment 10000.0 -31600.0 -1.83 13200.0 -30100.0 -2.28 -2.9043 -0.9941 1062658 Maybridge4_000594 CCOC(=O)C1C(C2c3ccccc3C1c4ccccc24)C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K23 mock treatment 34480.0 -7090.0 -0.41 38080.0 -5220.0 -0.39 -0.5697 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 K24 mock treatment 33840.0 -7730.0 -0.45 34120.0 -9180.0 -0.69 -0.8079 -0.9775 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L01 compound treatment 13760.0 -27800.0 -1.61 13440.0 -29900.0 -2.26 -2.7374 -0.9863 3062656 Maybridge4_000595 CCCCN(C(C)C)S(=O)(=O)c1ccc(C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L02 compound treatment 31360.0 -10200.0 -0.59 39120.0 -4180.0 -0.32 -0.6418 -0.9568 3178740 Maybridge4_000596 FC(F)(F)c1cccc(c1)/C(=C/C=C/c2ccccc2)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L03 compound treatment 34960.0 -6610.0 -0.38 44400.0 1110.0 0.08 -0.2118 -0.54 3062657 Maybridge4_000597 O=C1NC(=O)C(=CC2CCC=CC2)C(=O)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L04 compound treatment 28200.0 -13400.0 -0.77 34800.0 -8500.0 -0.64 -1.0025 -0.9957 1174872 Maybridge4_000598 Fc1cccc(F)c1C(=O)Nc2cccc(NC(=O)c3c(F)cccc3F)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L05 compound treatment 31560.0 -10000.0 -0.58 38840.0 -4460.0 -0.34 -0.6486 -0.9667 3178741 Maybridge4_000599 COc1ccc(CC/N=C/c2ccc3OCOc3c2)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L06 compound treatment 28480.0 -13100.0 -0.76 34520.0 -8780.0 -0.66 -1.006 -0.9978 3062658 Maybridge4_000600 FC(F)(F)c1cc(C#CCN2CCCCC2)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L07 compound treatment 30800.0 -10800.0 -0.62 34920.0 -8380.0 -0.63 -0.8896 -1.0 3178820 Maybridge4_000601 CC(C)NC(=S)N1CCCN2C1c3ccccc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L08 compound treatment 11880.0 -29700.0 -1.72 19240.0 -24100.0 -1.82 -2.504 -0.9996 3062659 Maybridge4_000602 FC(F)(F)c1cccc(c1C(=O)OCC(=O)c2ccc(Cl)cc2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L09 compound treatment 32240.0 -9330.0 -0.54 39440.0 -3860.0 -0.29 -0.5887 -0.9581 1236762 Maybridge4_000603 S=C(Nc1ccccc1)Nc2ccccc2n3cccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L10 compound treatment 23400.0 -18200.0 -1.05 28560.0 -14700.0 -1.12 -1.5332 -0.9996 3062660 Maybridge4_000604 COc1ccc(OC)c(c1)S(=O)(=O)c2ccc(Br)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L11 compound treatment 29080.0 -12500.0 -0.72 39960.0 -3340.0 -0.25 -0.6903 -0.9005 1138158 Maybridge4_000605 COc1ccc(OCCC(=O)NN)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L12 compound treatment 26160.0 -15400.0 -0.89 34280.0 -9020.0 -0.68 -1.1139 -0.9912 3062661 Maybridge4_000606 CN(C)C(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L13 compound treatment 27920.0 -13700.0 -0.79 32360.0 -10900.0 -0.83 -1.1446 -0.9997 3178821 Maybridge4_000607 OC(Cc1ccccc1)(c2ccccc2)c3ccccc3/N=C/c4ccc5OCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L14 compound treatment 12160.0 -29400.0 -1.7 15840.0 -27500.0 -2.08 -2.6745 -0.9951 3178822 Maybridge4_000608 Fc1cccc(N(Cc2cccnc2)C(=S)Nc3ccc(Cl)c(Cl)c3)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L15 compound treatment 16360.0 -25200.0 -1.46 20840.0 -22500.0 -1.7 -2.2348 -0.9972 3062708 Maybridge4_000609 Cc1c(C)c(C)c(CSc2ccccn2)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L16 compound treatment 35600.0 -5970.0 -0.35 38360.0 -4940.0 -0.37 -0.5088 -0.9993 3062709 Maybridge4_000610 CC(C)NC(=O)NCc1c(F)cccc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L17 compound treatment 28240.0 -13300.0 -0.77 33320.0 -9980.0 -0.76 -1.0801 -0.9999 3062710 Maybridge4_000611 Cc1c(C)c(C)c(C(=O)/C=N/N)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L18 compound treatment 28400.0 -13200.0 -0.76 34040.0 -9260.0 -0.7 -1.035 -0.9991 3062711 Maybridge4_000612 CCc1cccc(C(C)C)c1NC(=O)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L19 compound treatment 32440.0 -9130.0 -0.53 38880.0 -4420.0 -0.33 -0.6104 -0.9754 3062712 Maybridge4_000613 COc1ccc(NC(=S)NCCCC2C=NN=C2O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L20 compound treatment 32200.0 -9370.0 -0.54 37440.0 -5860.0 -0.44 -0.6974 -0.9949 3062713 Maybridge4_000614 CC(C)(C)C1=C(C#N)C(C(=C(NC(=O)NC(=O)c2c(F)cccc2Cl)O1)C#N)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L21 compound treatment 34280.0 -7290.0 -0.42 42000.0 -1300.0 -0.1 -0.3681 -0.8486 1309274 Maybridge4_000615 Cc1cc(C)c(C(=O)Nc2ccc(C)c(C)c2)c(CC(C)(C)C(=O)O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L22 compound treatment 35440.0 -6130.0 -0.36 41200.0 -2100.0 -0.16 -0.3634 -0.9339 3178823 Maybridge4_000616 OCC(CO)(CO)NC(=S)Nc1cc(Cl)cc(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L23 mock treatment 38040.0 -3530.0 -0.2 39920.0 -3380.0 -0.26 -0.3254 -0.994 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 L24 mock treatment 38400.0 -3170.0 -0.18 40840.0 -2460.0 -0.19 -0.2614 -1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M01 compound treatment 42960.0 1390.0 0.08 40240.0 -3060.0 -0.23 -0.1067 -0.4357 1443995 Maybridge4_000617 CCCc1ccc(Oc2ccc(NC(=O)C3CC3C(=O)O)cn2)c(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M02 compound treatment 33280.0 -8290.0 -0.48 39200.0 -4100.0 -0.31 -0.5589 -0.9775 2105374 Maybridge4_000618 Oc1ccc(cc1)C(C#N)N2CCN(CC2)C(C#N)c3ccc(O)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M03 compound treatment 11360.0 -30200.0 -1.75 11040.0 -32300.0 -2.44 -2.9642 -0.9867 1235908 Maybridge4_000619 Cc1nc(cs1)c2cc(C#N)c(SCCC(=O)OC(C)(C)C)nc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M04 compound treatment 24480.0 -17100.0 -0.99 34480.0 -8820.0 -0.67 -1.1721 -0.9815 1332220 Maybridge4_000620 COc1ccc(cc1)C(=O)NC2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M05 compound treatment 36560.0 -5010.0 -0.29 37520.0 -5780.0 -0.44 -0.5145 -0.9803 3178824 Maybridge4_000621 CN1C2CCC1CC(C2)NC(=O)Cc3ccccc3F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M06 compound treatment 33040.0 -8530.0 -0.49 40760.0 -2540.0 -0.19 -0.4852 -0.9151 3062715 Maybridge4_000622 CCNC(=O)Oc1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M07 compound treatment 27200.0 -14400.0 -0.83 34800.0 -8500.0 -0.64 -1.0435 -0.9918 3062716 Maybridge4_000623 CN(C)/C=C/C(=O)c1c(O)cc(C)oc1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M08 compound treatment 6600.0 -35000.0 -2.03 11600.0 -31700.0 -2.4 -3.1292 -0.9965 1250275 Maybridge4_000624 COc1ccccc1C2CCN(CC2)C(=O)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M09 compound treatment 18240.0 -23300.0 -1.35 27600.0 -15700.0 -1.19 -1.7959 -0.9979 1731106 Maybridge4_000625 COc1ccc(Br)cc1COC(=O)C2c3ccccc3Oc4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M10 compound treatment 21600.0 -20000.0 -1.16 30560.0 -12700.0 -0.96 -1.4999 -0.9959 1917572 Maybridge4_000626 CCOc1ccc2[nH]c(SCc3c(F)c(F)c(F)c(F)c3F)nc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M11 compound treatment 22040.0 -19500.0 -1.13 29840.0 -13500.0 -1.02 -1.5204 -0.9986 1003070 Maybridge4_000627 Cc1ccc(cc1)S(=O)(=O)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M12 compound treatment 25360.0 -16200.0 -0.94 27040.0 -16300.0 -1.23 -1.5342 -0.9911 3062717 Maybridge4_000628 CSc1nc2c(=S)[nH]c(=S)[nH]c2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M13 compound treatment 30000.0 -11600.0 -0.67 32480.0 -10800.0 -0.82 -1.053 -0.9951 3062718 Maybridge4_000629 O/N=C(/C(=N/O)/c1ccccc1)\c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M14 compound treatment 35000.0 -6570.0 -0.38 36920.0 -6380.0 -0.48 -0.6105 -0.9931 1781230 Maybridge4_000630 CCOC(=O)CNc1n[nH]c(=O)[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M15 compound treatment 20680.0 -20900.0 -1.21 23920.0 -19400.0 -1.47 -1.893 -0.9955 3062719 Maybridge4_000631 Cc1cc(C)nc(S/C=C/C(=O)c2ccc(Cl)cc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M16 compound treatment 36600.0 -4970.0 -0.29 33560.0 -9740.0 -0.74 -0.7248 -0.916 1718236 Maybridge4_000632 Cn1c(=O)cc(N2CCOCC2)c3c(=O)n(c4ccccc4)c(=O)n(c5ccccc5)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M17 compound treatment 31400.0 -10200.0 -0.59 33240.0 -10100.0 -0.76 -0.9549 -0.992 3178825 Maybridge4_000633 CC(=O)NC1=NN(C(N1C(=O)C)c2cccc3ccccc23)C(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M18 compound treatment 27120.0 -14500.0 -0.84 38520.0 -4780.0 -0.36 -0.8477 -0.9294 1286292 Maybridge4_000634 O=C(NC(C(=O)c1ccccc1)n2cnccc2=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M19 compound treatment 16440.0 -25100.0 -1.46 14600.0 -28700.0 -2.17 -2.5655 -0.9811 1171458 Maybridge4_000635 OC(COCc1ccccc1)Cn2c3ccccc3c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M20 compound treatment 36360.0 -5210.0 -0.3 36400.0 -6900.0 -0.52 -0.5826 -0.9662 3062720 Maybridge4_000636 C/S(=N\S(=O)(=O)c1ccc(C)cc1)/c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M21 compound treatment 29880.0 -11700.0 -0.68 36840.0 -6460.0 -0.49 -0.8245 -0.9871 1311339 Maybridge4_000637 O=C(C(C#N)c1nc2ccccc2[nH]1)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M22 compound treatment 25920.0 -15700.0 -0.91 30880.0 -12400.0 -0.94 -1.3058 -0.9998 1645478 Maybridge4_000638 COC(=O)C1C([C@H]2c3ccccc3[C@@H]1c4ccccc24)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M23 mock treatment 38640.0 -2930.0 -0.17 43400.0 105.0 0.01 -0.1145 -0.6733 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 M24 mock treatment 37800.0 -3770.0 -0.22 40680.0 -2620.0 -0.2 -0.2945 -0.9988 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N01 compound treatment 44000.0 2430.0 0.14 47240.0 3950.0 0.3 0.3106 0.941 1273203 Maybridge4_000639 CN(C)CC1(CC(=O)O)CCCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N02 compound treatment 39200.0 -2370.0 -0.14 37800.0 -5500.0 -0.42 -0.3913 -0.8933 3178826 Maybridge4_000640 NN/C(=N/S(=O)(=O)c1ccccc1)/N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N03 compound treatment 440.0 -41100.0 -2.38 480.0 -42800.0 -3.24 -3.9768 -0.9886 3062722 Maybridge4_000641 O=C1NC(=O)C(=C/C=C/c2ccccc2)C(=O)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N04 compound treatment 27120.0 -14500.0 -0.84 30840.0 -12500.0 -0.94 -1.2587 -0.9983 1678177 Maybridge4_000642 COc1cccc(OC)c1C(=O)Nc2ccccc2NC(=O)c3c(OC)cccc3OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N05 compound treatment 29680.0 -11900.0 -0.69 33240.0 -10100.0 -0.76 -1.0254 -0.9988 1073885 Maybridge4_000643 CCOc1ccc(CCC(=O)O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N06 compound treatment 31360.0 -10200.0 -0.59 33520.0 -9780.0 -0.74 -0.9416 -0.9939 3178827 Maybridge4_000644 CS/C(=N\S(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)/N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N07 compound treatment 33680.0 -7890.0 -0.46 37200.0 -6100.0 -0.46 -0.6496 -1.0 3062723 Maybridge4_000645 Oc1noc(O)c1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N08 compound treatment 29000.0 -12600.0 -0.73 31680.0 -11600.0 -0.88 -1.1368 -0.9956 3062724 Maybridge4_000646 NC(=S)NC1CC2CC1C=C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N09 compound treatment 29200.0 -12400.0 -0.72 33600.0 -9700.0 -0.73 -1.0258 -0.9999 3178828 Maybridge4_000647 CCNc1cc(N)[n+](CC)c2[nH]nc(N)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N10 compound treatment 22240.0 -19300.0 -1.12 28960.0 -14300.0 -1.09 -1.5593 -0.9999 1512370 Maybridge4_000648 COc1ccc(cc1CN2CCOCC2)c3cc(c4ccccc4)c(nn3)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N11 compound treatment 22520.0 -19100.0 -1.1 29840.0 -13500.0 -1.02 -1.5007 -0.9992 1288584 Maybridge4_000649 S=C(NC1CC2CC1C=C2)N(CCC#N)Cc3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N12 compound treatment 27480.0 -14100.0 -0.82 33880.0 -9420.0 -0.71 -1.0813 -0.9977 3178829 Maybridge4_000650 CC(=O)NCc1c(F)cccc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N13 compound treatment 16840.0 -24700.0 -1.43 20360.0 -22900.0 -1.74 -2.2408 -0.9955 1566685 Maybridge4_000651 CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)Nc2cccc(SC)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N14 compound treatment 31320.0 -10300.0 -0.59 31040.0 -12300.0 -0.93 -1.076 -0.9768 3062725 Maybridge4_000652 Fc1cccc(Cl)c1CSc2ccccc2C3=NCCCN3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N15 compound treatment 13920.0 -27700.0 -1.6 17880.0 -25400.0 -1.92 -2.4932 -0.9959 3178830 Maybridge4_000653 Cc1c(C)c(C)c(CSC2=NCCS2)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N16 compound treatment 31280.0 -10300.0 -0.6 34240.0 -9060.0 -0.69 -0.9063 -0.9976 3062726 Maybridge4_000654 Clc1cc(C[n+]2ccccc2)c3OCOCc3c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N17 compound treatment 30680.0 -10900.0 -0.63 33160.0 -10100.0 -0.77 -0.9887 -0.9953 3062727 Maybridge4_000655 Cn1c(S)nnc1CC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N18 compound treatment 21840.0 -19700.0 -1.14 20880.0 -22400.0 -1.7 -2.0081 -0.9815 3178831 Maybridge4_000656 CC1CC(C)CN(C1)S(=O)(=O)c2c(C)c(C)c(C)c(C)c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N19 compound treatment 17800.0 -23800.0 -1.38 18320.0 -25000.0 -1.89 -2.3107 -0.9879 3178832 Maybridge4_000657 N#Cc1cccc(CSc2nnc(SCc3cccc(C#N)c3)s2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N20 compound treatment 23040.0 -18500.0 -1.07 27320.0 -16000.0 -1.21 -1.6143 -0.9982 3062728 Maybridge4_000658 CC1(C)ON(C(=N1)NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N21 compound treatment 30280.0 -11300.0 -0.65 32000.0 -11300.0 -0.85 -1.0672 -0.9913 3178833 Maybridge4_000659 CC1N=C(SCC#N)N2C(C)N=C(SCC#N)N12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N22 compound treatment 30120.0 -11500.0 -0.66 35560.0 -7740.0 -0.59 -0.8832 -0.9981 1490971 Maybridge4_000660 Nc1ccccc1C(=O)NCc2c(F)cccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N23 mock treatment 33600.0 -7970.0 -0.46 34480.0 -8820.0 -0.67 -0.7984 -0.9839 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 N24 mock treatment 34120.0 -7450.0 -0.43 38120.0 -5180.0 -0.39 -0.5823 -0.9988 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O01 compound treatment 41920.0 348.0 0.02 44240.0 945.0 0.07 0.0648 0.8722 3178834 Maybridge4_000661 COc1ccccc1C2OC(=O)C[C@H]2C(=O)Oc3cccc(c3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O02 compound treatment 42680.0 1110.0 0.06 45560.0 2270.0 0.17 0.1666 0.9101 3178835 Maybridge4_000662 FC(F)(F)c1cc(NC(=S)NCCN2CCNC2=O)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O03 compound treatment 30960.0 -10600.0 -0.61 38960.0 -4340.0 -0.33 -0.6668 -0.9568 1251917 Maybridge4_000663 Cc1ccc(OC(C)(C)C(=O)Nc2ccc(Oc3ccc(F)cc3F)nc2)c4CCCc41 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O04 compound treatment 33640.0 -7930.0 -0.46 36440.0 -6860.0 -0.52 -0.6919 -0.9982 3178836 Maybridge4_000664 Cc1ccccc1NC2=NCC(C)(C)S2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O05 compound treatment 27960.0 -13600.0 -0.79 35320.0 -7980.0 -0.6 -0.9845 -0.9913 1342095 Maybridge4_000665 NC(=O)C1c2ccccc2Oc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O06 compound treatment 28360.0 -13200.0 -0.77 36480.0 -6820.0 -0.52 -0.9061 -0.9815 3178916 Maybridge4_000666 CC(C)(C)NC(=O)Oc1ccc(Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O07 compound treatment 40520.0 -1050.0 -0.06 43480.0 185.0 0.01 -0.0332 -0.5309 1101019 Maybridge4_000667 CC(C)(C)c1cc(c2oc(cc(=O)c2c1)C(=O)O)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O08 compound treatment 36040.0 -5530.0 -0.32 36640.0 -6660.0 -0.5 -0.5829 -0.9762 1485865 Maybridge4_000668 Clc1ccc(OC2CN(C2)C(=O)NCC=C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O09 compound treatment 27320.0 -14300.0 -0.83 33000.0 -10300.0 -0.78 -1.1349 -0.9996 3178917 Maybridge4_000669 O=C(Oc1ccc2ccccc2c1)C3c4ccccc4Oc5ccccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O10 compound treatment 29000.0 -12600.0 -0.73 38760.0 -4540.0 -0.34 -0.7578 -0.9411 1074403 Maybridge4_000670 C1CCC(CC1)Nc2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O11 compound treatment 35440.0 -6130.0 -0.36 40000.0 -3300.0 -0.25 -0.4276 -0.985 1171317 Maybridge4_000671 COc1cc(OC)cc(c1)C(C)(C)OC(=O)NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O12 compound treatment 36360.0 -5210.0 -0.3 41480.0 -1820.0 -0.14 -0.3107 -0.9364 1302360 Maybridge4_000672 OC(=O)Cc1cncc(Br)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O13 compound treatment 33360.0 -8210.0 -0.48 38320.0 -4980.0 -0.38 -0.6027 -0.9933 3063089 Maybridge4_000673 C/C(=N\O)/c1c(O)c2ccccc2n(C)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O14 compound treatment 40280.0 -1290.0 -0.07 43560.0 265.0 0.02 -0.0388 -0.5001 1915396 Maybridge4_000674 CC1(C)OC2C(CO)OC(C2O1)n3cnc4c(=O)[nH]cnc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O15 compound treatment 23680.0 -17900.0 -1.04 31800.0 -11500.0 -0.87 -1.3483 -0.9962 1665055 Maybridge4_000675 CC(=O)OCc1ccccc1Sc2ccccc2C(=O)NCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O16 compound treatment 33600.0 -7970.0 -0.46 38520.0 -4780.0 -0.36 -0.5822 -0.9926 3063091 Maybridge4_000676 CN1C(=O)/C(=C\NCc2ccccc2)/C(=O)c3c1n(C)c(=O)n(C)c3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O17 compound treatment 34960.0 -6610.0 -0.38 39480.0 -3820.0 -0.29 -0.4751 -0.9903 3178918 Maybridge4_000677 COC(=O)c1cc(=O)nc2O[C@@H]3C(O)[C@@H](CO)OC3n21 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O18 compound treatment 33800.0 -7770.0 -0.45 42000.0 -1300.0 -0.1 -0.3877 -0.8413 1458724 Maybridge4_000678 OC(=O)CCC1(CC2CC3CC(O)(C2)C1)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O19 compound treatment 31760.0 -9810.0 -0.57 29520.0 -13800.0 -1.04 -1.1393 -0.9593 3178919 Maybridge4_000679 CCn1c2ccc(Cl)cc2c3cc(Cl)ccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O20 compound treatment 22520.0 -19100.0 -1.1 26440.0 -16900.0 -1.28 -1.6827 -0.9974 1547077 Maybridge4_000680 Cc1ccc(cc1)S(=O)(=O)N=S(Cc2ccccc2)Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O21 compound treatment 40600.0 -973.0 -0.06 38280.0 -5020.0 -0.38 -0.3083 -0.8033 3063093 Maybridge4_000681 CC(C)(C)c1ccc(=O)[nH]n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O22 compound treatment 41080.0 -493.0 -0.03 39920.0 -3380.0 -0.26 -0.2008 -0.7812 3178920 Maybridge4_000682 Brc1ccc(NC(=O)N2NC(=O)[C@H]([C@@H]2c3ccccc3)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O23 mock treatment 38720.0 -2850.0 -0.17 46600.0 3310.0 0.25 0.06 0.2002 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 O24 mock treatment 52000.0 10400.0 0.6 42480.0 -815.0 -0.06 0.3836 0.6316 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P01 compound treatment 41880.0 308.0 0.02 41560.0 -1740.0 -0.13 -0.0803 -0.6056 3063094 Maybridge4_000683 COC(=O)/C=C/c1cn(C2OCC(CO)C2O)c(=O)[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P02 compound treatment 34160.0 -7410.0 -0.43 38720.0 -4580.0 -0.35 -0.5485 -0.9943 3178921 Maybridge4_000684 NNC(=O)CS(=O)Cc1cccc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P03 compound treatment 4640.0 -36900.0 -2.14 4640.0 -38700.0 -2.93 -3.582 -0.9882 3063095 Maybridge4_000685 O=C1NC(=O)C(=Cc2cccc3ccccc23)C(=O)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P04 compound treatment 22320.0 -19300.0 -1.12 23160.0 -20100.0 -1.52 -1.8664 -0.9882 3178922 Maybridge4_000686 O/N=C/c1ccc(o1)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P05 compound treatment 23320.0 -18300.0 -1.06 29240.0 -14100.0 -1.06 -1.5001 -1.0 1352669 Maybridge4_000687 COc1cccc(NC(=S)NC(Cc2ccccc2)c3ccccc3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P06 compound treatment 26120.0 -15500.0 -0.9 33960.0 -9340.0 -0.71 -1.1327 -0.9931 1145524 Maybridge4_000688 Clc1ccc(Cl)c(NC(=S)Nc2ccc(nc2)N3CCOCC3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P07 compound treatment 24960.0 -16600.0 -0.96 29480.0 -13800.0 -1.05 -1.42 -0.9991 1152510 Maybridge4_000689 COc1ccc(CSC2=C(C#N)C(=O)NC3(CCCCC3)S2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P08 compound treatment 25600.0 -16000.0 -0.93 31200.0 -12100.0 -0.92 -1.3017 -1.0 3063149 Maybridge4_000690 Clc1ccccc1NC(=O)CC2SC(=NC2=O)NC3CC4CC3C=C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P09 compound treatment 31440.0 -10100.0 -0.59 32120.0 -11200.0 -0.85 -1.0132 -0.9841 3178923 Maybridge4_000691 CCNc1cc(N)[n+](CC)c2[nH]nc(/N=C/c3cc(Cl)cc(Cl)c3O)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P10 compound treatment 28360.0 -13200.0 -0.77 31400.0 -11900.0 -0.9 -1.178 -0.9967 3063150 Maybridge4_000692 N/C(=N\O)/CN1CCCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P11 compound treatment 26520.0 -15100.0 -0.87 29960.0 -13300.0 -1.01 -1.3304 -0.9973 1138088 Maybridge4_000693 S=C(NC1CC2CC1C=C2)N(CCC#N)CC3CCCO3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P12 compound treatment 13880.0 -27700.0 -1.6 20400.0 -22900.0 -1.73 -2.3599 -0.9993 3063152 Maybridge4_000694 Fc1cccc(Cl)c1CSC2=NCCN2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P13 compound treatment 27000.0 -14600.0 -0.84 32320.0 -11000.0 -0.83 -1.1844 -1.0 1637772 Maybridge4_000695 Cc1onc(c1C(=O)N2CCCN3C2c4ccccc4C3=O)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P14 compound treatment 30400.0 -11200.0 -0.65 33600.0 -9700.0 -0.73 -0.9766 -0.998 3063153 Maybridge4_000696 Nn1c(nc2ccccc2c1=O)C(=O)N3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P15 compound treatment 21040.0 -20500.0 -1.19 25600.0 -17700.0 -1.34 -1.7883 -0.9983 1322891 Maybridge4_000697 CCOC(=O)CCc1ccc(OCc2c(C)c(C)c(C)c(C)c2C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P16 compound treatment 22440.0 -19100.0 -1.11 25160.0 -18100.0 -1.37 -1.7545 -0.9944 3063154 Maybridge4_000698 Cc1c(C)c(C)c(c(C)c1C)S(=O)(=O)NCCCN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P17 compound treatment 8720.0 -32900.0 -1.9 11400.0 -31900.0 -2.41 -3.0531 -0.9931 1180785 Maybridge4_000699 Cc1c(C)c(C)c(C(=O)CCc2cccc(NC(=O)C3CCC3)c2)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P18 compound treatment 21640.0 -19900.0 -1.15 35000.0 -8300.0 -0.63 -1.2606 -0.959 3063155 Maybridge4_000700 Cc1c(C)c(C)c(c(C)c1C)S(=O)(=O)NC(=N)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P19 compound treatment 9760.0 -31800.0 -1.84 12880.0 -30400.0 -2.3 -2.9312 -0.9939 3178924 Maybridge4_000701 N/C(=N\O)/Cc1nc(cs1)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P20 compound treatment 11080.0 -30500.0 -1.77 12440.0 -30900.0 -2.34 -2.9007 -0.9905 3063157 Maybridge4_000702 Cc1nnsc1C(=O)NC(=O)Nc2cc(Cl)cc(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P21 compound treatment 33880.0 -7690.0 -0.45 33720.0 -9580.0 -0.72 -0.8276 -0.9727 3178925 Maybridge4_000703 CC1(C)NN(C(=N1)S)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P22 compound treatment 32920.0 -8650.0 -0.5 29160.0 -14100.0 -1.07 -1.111 -0.9403 3063158 Maybridge4_000704 CSc1nc(nc(SC)c1Cl)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P23 mock treatment 37640.0 -3930.0 -0.23 38120.0 -5180.0 -0.39 -0.4381 -0.9668 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2050 P24 mock treatment 40960.0 -613.0 -0.04 39360.0 -3940.0 -0.3 -0.2357 -0.7858 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A01 compound treatment 85000.0 22300.0 1.29 67400.0 15200.0 1.15 1.726 0.9984 1580862 Maybridge4_000705 CC1CC(C)CN(C1)c2ccc(NC(=O)c3ccc(Cl)cc3)cc2C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A02 compound treatment 63400.0 664.0 0.04 48160.0 -4030.0 -0.31 -0.1887 -0.6132 3063159 Maybridge4_000706 Cc1nn(C)c(Cl)c1S(=O)(=O)Nc2ccc(C)cc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A03 compound treatment 75920.0 13200.0 0.76 61400.0 9210.0 0.7 1.0329 0.999 3178926 Maybridge4_000707 CN(C)/C=N/S(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A04 compound treatment 68880.0 6140.0 0.36 46480.0 -5710.0 -0.43 -0.0541 -0.0966 3178927 Maybridge4_000708 Clc1ccc(NC(=S)N2CCCC2c3cccs3)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A05 compound treatment 58520.0 -4220.0 -0.24 44720.0 -7470.0 -0.57 -0.5728 -0.9295 3063160 Maybridge4_000709 Cn1nccc1c2cc(F)cc(F)c2O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A06 compound treatment 75960.0 13200.0 0.77 50080.0 -2110.0 -0.16 0.4286 0.5476 3178928 Maybridge4_000710 O=C(NC(=O)c1ccc(cc1)S(=O)(=O)N2CCOCC2)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A07 compound treatment 62320.0 -416.0 -0.02 41200.0 -11000.0 -0.83 -0.6055 -0.7273 3063161 Maybridge4_000711 Fc1cccc(Cl)c1COC(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A08 compound treatment 68560.0 5820.0 0.34 53400.0 1210.0 0.09 0.3032 0.8673 3063162 Maybridge4_000712 CN(C)/C=C/C(=O)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A09 compound treatment 64240.0 1500.0 0.09 46680.0 -5510.0 -0.42 -0.2335 -0.5477 1674451 Maybridge4_000713 CN(NS(=O)(=O)c1cc(C)c(F)c(C)c1)c2cccc(Cl)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A10 compound treatment 50920.0 -11800.0 -0.68 44280.0 -7910.0 -0.6 -0.9077 -0.9978 3063163 Maybridge4_000714 CN(C)/C=C/1\SCc2ccccc2C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A11 compound treatment 21640.0 -41100.0 -2.38 12520.0 -39700.0 -3.0 -3.8071 -0.9934 3178929 Maybridge4_000715 Cc1onc(c1C(=O)c2ccc(F)cc2)c3c(Cl)cccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A12 compound treatment 61920.0 -816.0 -0.05 51800.0 -394.0 -0.03 -0.0545 -0.9752 1518860 Maybridge4_000716 COc1cccc(OC)c1C(=O)NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A13 compound treatment 60800.0 -1940.0 -0.11 46760.0 -5430.0 -0.41 -0.3702 -0.8683 1454624 Maybridge4_000717 CC1=C(O)C(=O)OC1c2c(F)cccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A14 compound treatment 35640.0 -27100.0 -1.57 25280.0 -26900.0 -2.04 -2.5506 -0.9917 3178930 Maybridge4_000718 Cc1nc(COc2cc(C)c(Cl)c(C)c2Cl)cs1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A15 compound treatment 64480.0 1740.0 0.1 56920.0 4730.0 0.36 0.3244 0.8727 3178931 Maybridge4_000719 Clc1ccc(NC(=O)C(C#N)C(=O)c2cccs2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A16 compound treatment 42760.0 -20000.0 -1.16 35280.0 -16900.0 -1.28 -1.7237 -0.9987 1203853 Maybridge4_000720 CC1N(CCc2sccc12)C(=S)NC(=O)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A17 compound treatment 69760.0 7020.0 0.41 58480.0 6290.0 0.48 0.6242 0.997 3178932 Maybridge4_000721 CSc1nc(NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)nn1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A18 compound treatment 44440.0 -18300.0 -1.06 41120.0 -11100.0 -0.84 -1.3423 -0.9932 3063213 Maybridge4_000722 FC(F)(F)c1cccc(NC(=S)C(C#N)C(=O)N2CCCC2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A19 compound treatment 64520.0 1780.0 0.1 56360.0 4170.0 0.32 0.2961 0.8921 3178933 Maybridge4_000723 Cc1nn(C)c(C)c1NC(=O)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A20 compound treatment 39760.0 -23000.0 -1.33 31440.0 -20800.0 -1.57 -2.0521 -0.9966 1654657 Maybridge4_000724 Brc1ccc(Nc2ncnc3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A21 compound treatment 69360.0 6620.0 0.38 52520.0 326.0 0.02 0.2888 0.7511 1162031 Maybridge4_000725 Nc1n[nH]c(NC2CCCCNC2=O)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A22 compound treatment 67240.0 4500.0 0.26 53520.0 1330.0 0.1 0.2555 0.9139 3179020 Maybridge4_000726 C1CCN2C(=CSC2=NC1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A23 mock treatment 72520.0 9780.0 0.57 59800.0 7610.0 0.58 0.8079 1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 A24 mock treatment 74840.0 12100.0 0.7 55520.0 3330.0 0.25 0.6739 0.9045 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B01 compound treatment 63880.0 1140.0 0.07 60120.0 7930.0 0.6 0.4711 0.7805 1499601 Maybridge4_000727 S=C(Nc1ccccc1)Nc2ccccc2c3nc4ccccc4[nH]3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B02 compound treatment 63240.0 504.0 0.03 60280.0 8090.0 0.61 0.4534 0.74 1693956 Maybridge4_000728 CSc1cc(nc(c1)c2ccc(Cl)cc2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B03 compound treatment 70200.0 7460.0 0.43 55920.0 3730.0 0.28 0.5052 0.9786 3063216 Maybridge4_000729 CN1CNC(=NC1)SCc2ccc(C#N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B04 compound treatment 65040.0 2300.0 0.13 54680.0 2490.0 0.19 0.2275 0.9858 3179021 Maybridge4_000730 FC(F)(F)c1ccccc1NC(=O)N/C=C/c2ccsc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B05 compound treatment 38200.0 -24500.0 -1.42 32640.0 -19600.0 -1.48 -2.0518 -0.9998 1138498 Maybridge4_000731 CN(C)c1ccc(cc1)C2Nc3cc(C)ccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B06 compound treatment 12920.0 -49800.0 -2.89 7240.0 -45000.0 -3.4 -4.447 -0.9966 3179022 Maybridge4_000732 CC1=CC(=O)N(C1=O)c2ccn(C)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B07 compound treatment 62800.0 63.8 0.0 42360.0 -9830.0 -0.74 -0.5237 -0.7036 3179023 Maybridge4_000733 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B08 compound treatment 13200.0 -49500.0 -2.87 10840.0 -41400.0 -3.13 -4.2428 -0.9991 3063218 Maybridge4_000734 CCCc1c(cnn1c2ccccc2)c3nc(no3)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B09 compound treatment 52080.0 -10700.0 -0.62 40480.0 -11700.0 -0.89 -1.0635 -0.9844 3179024 Maybridge4_000735 FC(F)(F)c1cccc(NC2(CCCCCC2)C#N)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B10 compound treatment 44040.0 -18700.0 -1.08 31880.0 -20300.0 -1.54 -1.8532 -0.9853 1512806 Maybridge4_000736 Cc1csc2c(ncnc12)N3CCSCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B11 compound treatment 63080.0 344.0 0.02 46800.0 -5390.0 -0.41 -0.2746 -0.6718 1281080 Maybridge4_000737 CS(=O)(=O)N1CCCN2C1c3ccccc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B12 compound treatment 61840.0 -896.0 -0.05 45880.0 -6310.0 -0.48 -0.3747 -0.7793 3179025 Maybridge4_000738 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2noc(n2)C3CCc4ccccc4O3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B13 compound treatment 56920.0 -5820.0 -0.34 38640.0 -13600.0 -1.03 -0.9637 -0.8925 3063220 Maybridge4_000739 Cc1c(C)c(C)c(CSCc2n[nH]c(=S)n2c3ccc(F)cc3)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B14 compound treatment 55960.0 -6780.0 -0.39 48880.0 -3310.0 -0.25 -0.455 -0.9766 3179026 Maybridge4_000740 Cc1csc2ncnc(Sc3ccccc3NS(=O)(=O)c4ccc(F)cc4)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B15 compound treatment 62040.0 -696.0 -0.04 54440.0 2250.0 0.17 0.0917 0.5248 3063222 Maybridge4_000741 CS/C(=N\C(=O)c1c(Cl)cccc1Cl)/N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B16 compound treatment 11440.0 -51300.0 -2.97 6760.0 -45400.0 -3.44 -4.5333 -0.9974 1691561 Maybridge4_000742 Cc1csc2ncnc(N3CCN(CC3)C(=S)NCC4CC4)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B17 compound treatment 64040.0 1300.0 0.08 48600.0 -3590.0 -0.27 -0.1389 -0.4921 1442583 Maybridge4_000743 Cc1ccc(C(=S)N)c(O)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B18 compound treatment 56880.0 -5860.0 -0.34 42240.0 -9950.0 -0.75 -0.7727 -0.9351 1597708 Maybridge4_000744 COc1cc2CCNC(=O)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B19 compound treatment 63120.0 384.0 0.02 45640.0 -6550.0 -0.5 -0.3351 -0.6747 3179027 Maybridge4_000745 FC(F)(F)Oc1ccc(cc1)n2c(=N)c(/N=C/c3ccc(cc3)C(F)(F)F)c(C#N)[nH]c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B20 compound treatment 72360.0 9620.0 0.56 56640.0 4450.0 0.34 0.6322 0.9708 1614161 Maybridge4_000746 Cc1csc(NC(=O)NS(=O)(=O)c2ccc(C)cc2)c1C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B21 compound treatment 4440.0 -58300.0 -3.38 3120.0 -49100.0 -3.71 -5.0149 -0.9989 3179028 Maybridge4_000747 Cc1csc(NC(=O)CSc2ccc(Cl)cc2)c1C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B22 compound treatment 66560.0 3820.0 0.22 53840.0 1650.0 0.12 0.2448 0.963 3063278 Maybridge4_000748 NNC(=S)Nc1ccccc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B23 mock treatment 72680.0 9940.0 0.58 61480.0 9290.0 0.7 0.9044 0.9951 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 B24 mock treatment 71760.0 9020.0 0.52 61720.0 9530.0 0.72 0.8796 0.9875 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C01 compound treatment 65120.0 2380.0 0.14 59600.0 7410.0 0.56 0.4941 0.8557 3179029 Maybridge4_000749 Cc1cc(C)n(Cc2c(Cl)cccc2Cl)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C02 compound treatment 49560.0 -13200.0 -0.76 40600.0 -11600.0 -0.88 -1.1604 -0.9976 3063279 Maybridge4_000750 CC1SCC(CS1)NC(=O)c2ccccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C03 compound treatment 71520.0 8780.0 0.51 55800.0 3610.0 0.27 0.5529 0.9574 3179030 Maybridge4_000751 CC(C)(C)n1cnnc1S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C04 compound treatment 68560.0 5820.0 0.34 51440.0 -754.0 -0.06 0.1982 0.5793 3179031 Maybridge4_000752 Cc1c(cnn1c2ccc(Cl)cc2)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C05 compound treatment 68920.0 6180.0 0.36 50520.0 -1670.0 -0.13 0.1638 0.4309 3063283 Maybridge4_000753 CN(C)/C=c/1\s\c(=C\C(=O)c2cccs2)\[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C06 compound treatment 47280.0 -15500.0 -0.9 36120.0 -16100.0 -1.22 -1.4935 -0.9886 3179032 Maybridge4_000754 Fc1ccc(c2ccc(o2)c3ccnn3S(=O)(=O)c4ccc(F)cc4F)c(F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C07 compound treatment 61680.0 -1060.0 -0.06 44320.0 -7870.0 -0.6 -0.4647 -0.7756 3063284 Maybridge4_000755 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NC(=N)N2CCSCC2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C08 compound treatment 55480.0 -7260.0 -0.42 41960.0 -10200.0 -0.77 -0.845 -0.9588 3179033 Maybridge4_000756 NC(=O)N/C(=N/O)/CSCc1ccc(Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C09 compound treatment 54720.0 -8020.0 -0.46 43240.0 -8950.0 -0.68 -0.8077 -0.983 3063285 Maybridge4_000757 Fc1cc(CSc2ccc(Cl)cc2)c3OCOCc3c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C10 compound treatment 72920.0 10200.0 0.59 55800.0 3610.0 0.27 0.6102 0.9387 1433051 Maybridge4_000758 CCOC(=O)Cc1nc(N)ncc1C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C11 compound treatment 45240.0 -17500.0 -1.01 35360.0 -16800.0 -1.27 -1.6178 -0.9936 1461982 Maybridge4_000759 Cc1onc(c1C(O)c2ccc(F)cc2)c3c(Cl)cccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C12 compound treatment 65960.0 3220.0 0.19 55840.0 3650.0 0.28 0.3272 0.9819 1346508 Maybridge4_000760 COc1ccc2C(NN(C)c3cccc(F)c3C#N)OC(=O)c2c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C13 compound treatment 63480.0 744.0 0.04 53400.0 1210.0 0.09 0.095 0.9413 3179034 Maybridge4_000761 CN(C)/C=N/C(=S)NC1CC2CC1C=C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C14 compound treatment 60560.0 -2180.0 -0.13 46480.0 -5710.0 -0.43 -0.395 -0.8768 1675569 Maybridge4_000762 C(N1CC(CN(Cc2ccccc2)C1)c3nn[nH]n3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C15 compound treatment 59680.0 -3060.0 -0.18 50080.0 -2110.0 -0.16 -0.2383 -0.9987 3063288 Maybridge4_000763 CNC(=O)n1cc(c(C)n1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C16 compound treatment 41000.0 -21700.0 -1.26 33360.0 -18800.0 -1.43 -1.8986 -0.9981 1260907 Maybridge4_000764 CC1N(CCc2sccc12)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C17 compound treatment 23640.0 -39100.0 -2.27 17200.0 -35000.0 -2.65 -3.4747 -0.997 1246781 Maybridge4_000765 CN(C)c1cccc(N(C)C)c1CNC(=O)c2ccccc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C18 compound treatment 45480.0 -17300.0 -1.0 36240.0 -16000.0 -1.21 -1.5609 -0.9956 3179035 Maybridge4_000766 FC(F)(F)c1cccc(NC(=O)C(C#N)C(=S)Nc2ccccc2Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C19 compound treatment 47480.0 -15300.0 -0.88 36440.0 -15800.0 -1.19 -1.4682 -0.9891 3063289 Maybridge4_000767 CNC(=O)N1CCCC(Cn2cccc2)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C20 compound treatment 48880.0 -13900.0 -0.8 41000.0 -11200.0 -0.85 -1.1668 -0.9996 1385501 Maybridge4_000768 Cc1ccc(cc1)c2csc(=N)n2c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C21 compound treatment 67840.0 5100.0 0.3 56280.0 4090.0 0.31 0.4278 0.9997 1144063 Maybridge4_000769 Clc1ccc(NC(=O)NC2CCCCNC2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C22 compound treatment 51880.0 -10900.0 -0.63 42800.0 -9390.0 -0.71 -0.9476 -0.9981 3179036 Maybridge4_000770 CC1CN=C(N1)SCc2c(C)c(C)c(C)c(C)c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C23 mock treatment 70920.0 8180.0 0.47 60760.0 8570.0 0.65 0.7938 0.9882 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 C24 mock treatment 70760.0 8020.0 0.46 60280.0 8090.0 0.61 0.7615 0.9908 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D01 compound treatment 68920.0 6180.0 0.36 53040.0 846.0 0.06 0.2986 0.8205 3063290 Maybridge4_000771 CSC1=NCCN1Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D02 compound treatment 19960.0 -42800.0 -2.48 12960.0 -39200.0 -2.97 -3.8524 -0.996 3179037 Maybridge4_000772 COC(=O)c1sc(cc1NC(=O)Nc2ccc(Cl)cc2)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D03 compound treatment 27600.0 -35100.0 -2.04 14000.0 -38200.0 -2.89 -3.4837 -0.9853 3063291 Maybridge4_000773 Cc1ccc(Cc2nc(cs2)c3ccc(Cl)cc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D04 compound treatment 68960.0 6220.0 0.36 63360.0 11200.0 0.85 0.8526 0.9279 3179038 Maybridge4_000774 FC(F)(F)c1cc(SC(=O)N/C=C/c2ccsc2)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D05 compound treatment 63840.0 1100.0 0.06 52840.0 646.0 0.05 0.0798 0.9912 1247834 Maybridge4_000775 CC(C)(C)CC(C)(C)N1CNC(=S)NC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D06 compound treatment 200.0 -62500.0 -3.62 240.0 -52000.0 -3.93 -5.3428 -0.9992 3179039 Maybridge4_000776 Cn1cc(Br)c(n1)N2C(=O)C=CC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D07 compound treatment 1400.0 -61300.0 -3.55 1880.0 -50300.0 -3.81 -5.2058 -0.9994 3179040 Maybridge4_000777 COc1cc(cc(OC)c1OC)C(O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D08 compound treatment 53400.0 -9340.0 -0.54 38120.0 -14100.0 -1.07 -1.1358 -0.9506 3063293 Maybridge4_000778 CCCc1nn(cc1C(=O)Nc2ccc(Cl)cc2)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D09 compound treatment 20920.0 -41800.0 -2.42 17960.0 -34200.0 -2.59 -3.5455 -0.9994 1432923 Maybridge4_000779 CC(NC(=O)c1c(C)onc1c2ccccc2Cl)c3ccc(C)cc3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D10 compound treatment 59280.0 -3460.0 -0.2 45640.0 -6550.0 -0.5 -0.4924 -0.9204 3179041 Maybridge4_000780 FC(F)(F)c1c(cnn1c2ccc(Cl)cc2)C(=O)NCCc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D11 compound treatment 33680.0 -29100.0 -1.68 30600.0 -21600.0 -1.63 -2.3462 -0.9999 3179119 Maybridge4_000781 COc1cc(cc(OC)c1OC)C(=O)N2/C(=N/c3ccccc3Cl)/SC(=C)C2(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D12 compound treatment 1680.0 -61100.0 -3.54 1720.0 -50500.0 -3.82 -5.2029 -0.9993 3062512 Maybridge4_000782 COC(=O)c1cnc(NN2C(=O)C=C(C)C2=O)nc1C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D13 compound treatment 64560.0 1820.0 0.11 48360.0 -3830.0 -0.29 -0.1305 -0.4225 1164825 Maybridge4_000783 NNC(=O)Oc1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D14 compound treatment 66280.0 3540.0 0.21 51640.0 -554.0 -0.04 0.1155 0.5514 3179120 Maybridge4_000784 COC(=O)c1sccc1Oc2ccc(cc2NC(=O)/C=C/C(=O)O)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D15 compound treatment 59480.0 -3260.0 -0.19 50320.0 -1870.0 -0.14 -0.2337 -0.9901 3062514 Maybridge4_000785 Clc1cccc(Cl)c1C(=O)N=C2NCCCN2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D16 compound treatment 54920.0 -7820.0 -0.45 42800.0 -9390.0 -0.71 -0.823 -0.9763 3179121 Maybridge4_000786 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D17 compound treatment 47120.0 -15600.0 -0.9 39240.0 -13000.0 -0.98 -1.3331 -0.9992 3062515 Maybridge4_000787 CCOC(=O)C1=C(C)NC(=NC1c2cccs2)SC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D18 compound treatment 48320.0 -14400.0 -0.84 38680.0 -13500.0 -1.02 -1.3139 -0.9949 3179122 Maybridge4_000788 CCOC(=O)c1cnc(SCc2c(C)cc(C)cc2C)nc1C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D19 compound treatment 56560.0 -6180.0 -0.36 39880.0 -12300.0 -0.93 -0.9121 -0.9136 1515946 Maybridge4_000789 Fc1ccc(cc1)C(=O)ON(C2C3CC4CC(C3)CC2C4)C(=O)c5ccc(F)cc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D20 compound treatment 65480.0 2740.0 0.16 51880.0 -314.0 -0.02 0.0956 0.5949 1700551 Maybridge4_000790 COC(=O)CNS(=O)(=O)c1ccsc1C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D21 compound treatment 65480.0 2740.0 0.16 51960.0 -234.0 -0.02 0.0999 0.6245 1564868 Maybridge4_000791 Clc1cc(Cl)cc(c1)c2nnc(o2)N3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D22 compound treatment 72520.0 9780.0 0.57 58480.0 6290.0 0.48 0.7373 0.9962 3179123 Maybridge4_000792 COc1cc2ncnc(NCCCn3ccnc3)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D23 mock treatment 71240.0 8500.0 0.49 57720.0 5530.0 0.42 0.6442 0.9967 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 D24 mock treatment 69920.0 7180.0 0.42 56680.0 4490.0 0.34 0.5344 0.9949 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E01 compound treatment 64840.0 2100.0 0.12 54680.0 2490.0 0.19 0.2193 0.9779 3062517 Maybridge4_000793 CCc1nc2ccccc2nc1CC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E02 compound treatment 68880.0 6140.0 0.36 49960.0 -2230.0 -0.17 0.1321 0.3353 3179124 Maybridge4_000794 Cc1nc(S)c(C#N)c(C)c1Cc2ccc(Cl)cc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E03 compound treatment 59400.0 -3340.0 -0.19 46760.0 -5430.0 -0.41 -0.4275 -0.9407 3062519 Maybridge4_000795 Fc1cccc(CSCc2c(F)cccc2Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E04 compound treatment 68200.0 5460.0 0.32 53600.0 1410.0 0.11 0.2991 0.8956 3179125 Maybridge4_000796 CN(C)/C=N/S(=O)(=O)c1c(C)noc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E05 compound treatment 59200.0 -3540.0 -0.2 48000.0 -4190.0 -0.32 -0.3693 -0.9776 3062520 Maybridge4_000797 CCOc1ccccc1CCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E06 compound treatment 2040.0 -60700.0 -3.52 1840.0 -50400.0 -3.81 -5.1817 -0.9992 3179126 Maybridge4_000798 COc1ccc(NS(=O)(=O)c2ccc(Oc3c(C#N)cccc3C#N)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E07 compound treatment 58200.0 -4540.0 -0.26 42600.0 -9590.0 -0.73 -0.6993 -0.9055 3062522 Maybridge4_000799 Clc1ccc(cc1)S(=O)(=O)NC(=N)N2CCSCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E08 compound treatment 54360.0 -8380.0 -0.49 45360.0 -6830.0 -0.52 -0.7089 -0.9995 3179127 Maybridge4_000800 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)c2ccnc(NC(=O)Nc3ccccc3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E09 compound treatment 52080.0 -10700.0 -0.62 41040.0 -11200.0 -0.84 -1.0336 -0.9882 1521882 Maybridge4_000801 Clc1ccccc1C(=O)NC(=O)OCc2cccc(Oc3ccccc3)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E10 compound treatment 59880.0 -2860.0 -0.17 45720.0 -6470.0 -0.49 -0.4635 -0.8962 3179128 Maybridge4_000802 O=C(c1ccccc1)n2cc3SCc4ccccc4-c3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E11 compound treatment 60640.0 -2100.0 -0.12 48920.0 -3270.0 -0.25 -0.2611 -0.9461 1615025 Maybridge4_000803 Fc1ccc(cc1)C(=O)CCC(=O)c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E12 compound treatment 51440.0 -11300.0 -0.65 42480.0 -9710.0 -0.74 -0.9827 -0.9983 1276755 Maybridge4_000804 CN(n1cnc2ccsc2c1=O)S(=O)(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E13 compound treatment 58640.0 -4100.0 -0.24 51360.0 -834.0 -0.06 -0.2124 -0.8651 1254744 Maybridge4_000805 Clc1ccc(NC(=O)NC(=O)C2(CC3CC4CC(C3)C2)C4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E14 compound treatment 56200.0 -6540.0 -0.38 53160.0 966.0 0.07 -0.2161 -0.5602 1341148 Maybridge4_000806 O=C(Nc1ccccc1)n2nnc(n2)C3CN(Cc4ccccc4)CN(Cc5ccccc5)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E15 compound treatment 62800.0 63.8 0.0 47600.0 -4590.0 -0.35 -0.2433 -0.6996 1687071 Maybridge4_000807 CNC(=O)NCc1c(cccc1N(C)C)N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E16 compound treatment 38320.0 -24400.0 -1.41 33400.0 -18800.0 -1.42 -2.0062 -1.0 3179129 Maybridge4_000808 NC(=O)/C(=C/1\SC=C(N1Cc2ccccc2)c3ccccc3)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E17 compound treatment 56280.0 -6460.0 -0.37 48080.0 -4110.0 -0.31 -0.4847 -0.9958 3062558 Maybridge4_000809 CCc1cnc(/N=C/N(C)C)nc1c2c(F)cccc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E18 compound treatment 52480.0 -10300.0 -0.59 37600.0 -14600.0 -1.1 -1.2013 -0.9577 3179130 Maybridge4_000810 Cc1nc(c(s1)c2ccccc2)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E19 compound treatment 62760.0 23.8 0.0 50720.0 -1470.0 -0.11 -0.0779 -0.6983 3062560 Maybridge4_000811 COC(CNC(=S)Nc1ccccc1Cl)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E20 compound treatment 50240.0 -12500.0 -0.72 45520.0 -6670.0 -0.51 -0.8692 -0.9845 1542710 Maybridge4_000812 COc1ccc(CCn2nnc3ccccc3c2=O)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E21 compound treatment 66760.0 4020.0 0.23 50520.0 -1670.0 -0.13 0.0753 0.2836 1303354 Maybridge4_000813 CC(C)NC(=O)NC1CCCCNC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E22 compound treatment 102120.0 39400.0 2.28 90240.0 38000.0 2.88 3.6499 0.9934 3062562 Maybridge4_000814 O=C(N1C(Oc2ccccc12)c3ccc4OCOc4c3)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E23 mock treatment 69440.0 6700.0 0.39 56800.0 4610.0 0.35 0.5212 0.9986 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 E24 mock treatment 65800.0 3060.0 0.18 50040.0 -2150.0 -0.16 0.0102 0.0425 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F01 compound treatment 8320.0 -54400.0 -3.15 7800.0 -44400.0 -3.36 -4.6055 -0.9995 3179131 Maybridge4_000815 CN1CNC(=NC1)SCc2c(C)c(C)c(C)c(C)c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F02 compound treatment 65640.0 2900.0 0.17 57080.0 4890.0 0.37 0.3805 0.9364 3062563 Maybridge4_000816 Cn1ncc(C(=O)O)c1C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F03 compound treatment 65840.0 3100.0 0.18 49400.0 -2790.0 -0.21 -0.0224 -0.0806 3179132 Maybridge4_000817 C(SC1=NCCCN1C2CCCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F04 compound treatment 51240.0 -11500.0 -0.67 37800.0 -14400.0 -1.09 -1.2414 -0.9721 3062565 Maybridge4_000818 Cc1cc(SC(=O)N/C=C/c2ccco2)c(C)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F05 compound treatment 53720.0 -9020.0 -0.52 40560.0 -11600.0 -0.88 -0.9921 -0.9689 1151481 Maybridge4_000819 CC(=O)Nc1ccc(cc1)C2Nc3cc(C)ccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F06 compound treatment 60320.0 -2420.0 -0.14 47760.0 -4430.0 -0.34 -0.3363 -0.9248 1566379 Maybridge4_000820 O=C1CCC(=O)N1c2sc3CCCCc3c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F07 compound treatment 60120.0 -2620.0 -0.15 55000.0 2810.0 0.21 0.043 0.1649 1625831 Maybridge4_000821 CC(C)(C)n1c(n[nH]c1=S)c2ccncc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F08 compound treatment 34520.0 -28200.0 -1.63 28840.0 -23400.0 -1.77 -2.406 -0.9992 3179133 Maybridge4_000822 CCCc1c(cnn1c2ccccc2)C(=O)Sc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F09 compound treatment 63400.0 664.0 0.04 53040.0 846.0 0.06 0.0725 0.9702 1730421 Maybridge4_000823 CC(NC(=O)c1ccccc1C(=O)NC(C)c2ccc3OCCOc3c2)c4ccc5OCCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F10 compound treatment 60840.0 -1900.0 -0.11 48600.0 -3590.0 -0.27 -0.27 -0.9205 3062566 Maybridge4_000824 COC(=O)c1sccc1NN2C(=O)c3ccccc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F11 compound treatment 62600.0 -136.0 -0.01 46280.0 -5910.0 -0.45 -0.3221 -0.7195 1672433 Maybridge4_000825 Cc1ccc(cc1)S(=O)(=O)N(Cc2ccccc2)C(C#N)c3ccc4OCOc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F12 compound treatment 58360.0 -4380.0 -0.25 54320.0 2130.0 0.16 -0.0655 -0.218 3179134 Maybridge4_000826 COC(=O)c1cnc(NN2C(=O)CCC2=O)nc1C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F13 compound treatment 62840.0 104.0 0.01 59320.0 7130.0 0.54 0.3857 0.7149 3179135 Maybridge4_000827 FC(F)(F)c1cccc(NC(=S)N(CCC#N)C2CCCCC2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F14 compound treatment 60680.0 -2060.0 -0.12 42800.0 -9390.0 -0.71 -0.587 -0.8142 3062567 Maybridge4_000828 COC(=O)c1c(C)sc2c(cc(=O)[nH]c12)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F15 compound treatment 60640.0 -2100.0 -0.12 46640.0 -5550.0 -0.42 -0.3831 -0.8756 3062568 Maybridge4_000829 Clc1cccc(Cl)c1C(=O)N=C2NCCN2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F16 compound treatment 46160.0 -16600.0 -0.96 39400.0 -12800.0 -0.97 -1.3639 -1.0 1243939 Maybridge4_000830 COC(=O)c1ccsc1NC(=O)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F17 compound treatment 37560.0 -25200.0 -1.46 25240.0 -27000.0 -2.04 -2.4741 -0.9865 3062570 Maybridge4_000831 S=C1CCc2ccccc2N1Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F18 compound treatment 52480.0 -10300.0 -0.59 38400.0 -13800.0 -1.04 -1.1585 -0.9643 3179136 Maybridge4_000832 COC(=O)c1sccc1Oc2ccc(cc2NC(=O)c3ccc(Cl)cc3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F19 compound treatment 58640.0 -4100.0 -0.24 54560.0 2370.0 0.18 -0.0412 -0.1384 3179137 Maybridge4_000833 FC(F)(F)Oc1ccc(NC(=O)N/C(=C(\N=C/c2ccc(Cl)cc2)/C#N)/C#N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F20 compound treatment 62640.0 -96.3 -0.01 57720.0 5530.0 0.42 0.2918 0.6976 1627087 Maybridge4_000834 COC(=O)c1cc(OC)c(OC)cc1NC(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F21 compound treatment 67040.0 4300.0 0.25 54080.0 1890.0 0.14 0.2773 0.965 3062571 Maybridge4_000835 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2nnc(o2)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F22 compound treatment 67360.0 4620.0 0.27 54240.0 2050.0 0.15 0.2989 0.9661 3179138 Maybridge4_000836 COc1cc2ncnc(NCCCN3CCOCC3)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F23 mock treatment 63880.0 1140.0 0.07 54680.0 2490.0 0.19 0.1799 0.9018 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 F24 mock treatment 64440.0 1700.0 0.1 58040.0 5850.0 0.44 0.3827 0.8441 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G01 compound treatment 64080.0 1340.0 0.08 53120.0 926.0 0.07 0.1046 0.9986 3179214 Maybridge4_000837 CC(C)(C)C(=N)NS(=O)(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G02 compound treatment 57680.0 -5060.0 -0.29 47840.0 -4350.0 -0.33 -0.4402 -0.9983 1694181 Maybridge4_000838 O=C(Nc1ccccc1)Nc2ccccc2C(=O)NC3CCSC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G03 compound treatment 54000.0 -8740.0 -0.51 45680.0 -6510.0 -0.49 -0.7065 -0.9999 3179215 Maybridge4_000839 Cc1onc(c1CSc2nncn2C(C)(C)C)c3c(Cl)cccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G04 compound treatment 58560.0 -4180.0 -0.24 50040.0 -2150.0 -0.16 -0.2864 -0.9815 3062572 Maybridge4_000840 FC(F)(F)c1cccc(c1)C(C#N)c2cccc(c2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G05 compound treatment 54800.0 -7940.0 -0.46 42200.0 -9990.0 -0.76 -0.86 -0.9715 3179216 Maybridge4_000841 CN(C)/C=C/1\CC(=C(O)C1=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G06 compound treatment 52400.0 -10300.0 -0.6 41800.0 -10400.0 -0.79 -0.9798 -0.9909 3062573 Maybridge4_000842 CSc1cc(nn1S(=O)(=O)c2ccc(F)cc2F)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G07 compound treatment 59280.0 -3460.0 -0.2 49760.0 -2430.0 -0.18 -0.2719 -0.9991 3179217 Maybridge4_000843 Fc1ccc(NC(=O)NC(=O)Cc2c(F)cccc2Cl)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G08 compound treatment 56160.0 -6580.0 -0.38 39720.0 -12500.0 -0.94 -0.9371 -0.9203 1112281 Maybridge4_000844 Clc1ccc(cc1)S(=O)(=O)NCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G09 compound treatment 42480.0 -20300.0 -1.17 33640.0 -18600.0 -1.4 -1.8229 -0.996 3179218 Maybridge4_000845 CC(C)(C)c1nc(NC(=N)N)sc1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G10 compound treatment 54760.0 -7980.0 -0.46 47640.0 -4550.0 -0.34 -0.5705 -0.9896 1361037 Maybridge4_000846 N#CC1CN(Cc2cccs2)CN(Cc3cccs3)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G11 compound treatment 24400.0 -38300.0 -2.22 19480.0 -32700.0 -2.48 -3.3215 -0.9985 3062574 Maybridge4_000847 CSCC(CSC)OC(=O)c1c(C)onc1c2c(Cl)cccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G12 compound treatment 54680.0 -8060.0 -0.47 41320.0 -10900.0 -0.82 -0.9121 -0.9639 3179219 Maybridge4_000848 CN(n1cnc2ccsc2c1=O)S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G13 compound treatment 42480.0 -20300.0 -1.17 35720.0 -16500.0 -1.25 -1.7116 -0.9995 3179220 Maybridge4_000849 CN(C)/C=N/C1=C(C(=O)c2ccccc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G14 compound treatment 49600.0 -13100.0 -0.76 42560.0 -9630.0 -0.73 -1.0538 -0.9998 3062606 Maybridge4_000850 CC1N(CCc2sccc12)C(=O)c3ccc(cc3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G15 compound treatment 47560.0 -15200.0 -0.88 45200.0 -6990.0 -0.53 -0.9961 -0.9705 1282646 Maybridge4_000851 CN(C(=O)Nc1ccc(Cl)cc1)n2cnc3ccccc3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G16 compound treatment 6000.0 -56700.0 -3.29 2160.0 -50000.0 -3.79 -5.0024 -0.9975 3179221 Maybridge4_000852 CCOC(=O)/C(=C/1\SC=C(N1c2c(C)cccc2C)c3ccccc3)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G17 compound treatment 42160.0 -20600.0 -1.19 36040.0 -16200.0 -1.22 -1.7076 -0.9999 3062608 Maybridge4_000853 CNC(=O)n1cc(C)c(n1)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G18 compound treatment 47080.0 -15700.0 -0.91 37440.0 -14800.0 -1.12 -1.4311 -0.9947 1645665 Maybridge4_000854 Cc1ccc(cc1C)c2nn(CCO)c(=O)c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G19 compound treatment 55640.0 -7100.0 -0.41 45000.0 -7190.0 -0.54 -0.6758 -0.9904 1361478 Maybridge4_000855 Cc1nn(C)c(C)c1Nc2nc(N)n[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G20 compound treatment 59080.0 -3660.0 -0.21 49840.0 -2350.0 -0.18 -0.2758 -0.9963 3179222 Maybridge4_000856 CC1CN(CC(C)O1)C(=N)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G21 compound treatment 38920.0 -23800.0 -1.38 26440.0 -25800.0 -1.95 -2.3542 -0.9857 3062610 Maybridge4_000857 Clc1ccc(SS(=O)(=O)CS(=O)(=O)Sc2ccc(Cl)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G22 compound treatment 37400.0 -25300.0 -1.47 27120.0 -25100.0 -1.9 -2.38 -0.9919 3179223 Maybridge4_000858 Clc1ccc(cc1Cl)C2Nc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G23 mock treatment 62320.0 -416.0 -0.02 52800.0 606.0 0.05 0.0154 0.297 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 G24 mock treatment 60000.0 -2740.0 -0.16 49600.0 -2590.0 -0.2 -0.2509 -0.9944 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H01 compound treatment 2240.0 -60500.0 -3.51 1760.0 -50400.0 -3.82 -5.1778 -0.9991 3062611 Maybridge4_000859 CCN1CNC(=NC1)SCc2c(C)c(C)c(C)c(C)c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H02 compound treatment 69440.0 6700.0 0.39 57680.0 5490.0 0.42 0.5683 0.9994 3179224 Maybridge4_000860 CCOC(=O)c1sc(SC)nc1NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H03 compound treatment 42680.0 -20100.0 -1.16 36000.0 -16200.0 -1.23 -1.6884 -0.9996 1702677 Maybridge4_000861 COc1ccc(CCNC(=O)c2nc3ccccc3c(=O)[nH]2)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H04 compound treatment 54360.0 -8380.0 -0.49 43840.0 -8350.0 -0.63 -0.7903 -0.9915 1349117 Maybridge4_000862 CCOC(=O)c1cnn(C)c1NS(=O)(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H05 compound treatment 63200.0 464.0 0.03 49920.0 -2270.0 -0.17 -0.1027 -0.5896 3179225 Maybridge4_000863 COc1ccc(C/N=C/c2ccc(NC(=O)C)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H06 compound treatment 320.0 -62400.0 -3.62 200.0 -52000.0 -3.94 -5.34 -0.9991 3062612 Maybridge4_000864 FC(F)(F)c1ccc(NS(=O)(=O)c2ccc(cc2)N3C(=O)C=CC3=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H07 compound treatment 41200.0 -21500.0 -1.25 34000.0 -18200.0 -1.38 -1.8561 -0.9988 1216743 Maybridge4_000865 Clc1ccc(cc1)C(=C)NCc2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H08 compound treatment 48840.0 -13900.0 -0.81 38240.0 -14000.0 -1.06 -1.3162 -0.991 3062613 Maybridge4_000866 CSc1cc(nn1S(=O)(=O)c2ccc(C)cc2)c3ccc(F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H09 compound treatment 62560.0 -176.0 -0.01 49720.0 -2470.0 -0.19 -0.1396 -0.7446 1649762 Maybridge4_000867 CC1C(OCCN1C(=O)CCN2C(=O)c3ccccc3C2=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H10 compound treatment 1600.0 -61100.0 -3.54 1680.0 -50500.0 -3.82 -5.2083 -0.9993 3062614 Maybridge4_000868 COC(=O)c1scc(C)c1NN2C(=O)C=C(C)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H11 compound treatment 39320.0 -23400.0 -1.36 32480.0 -19700.0 -1.49 -2.0145 -0.9989 1683075 Maybridge4_000869 CC1CC(CC(C)(C)C1)N(CCC#N)S(=O)(=O)c2ccc(Br)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H12 compound treatment 44400.0 -18300.0 -1.06 37200.0 -15000.0 -1.13 -1.5537 -0.9995 3062615 Maybridge4_000870 COC(=O)c1sc2cc(sc2c1C)c3ccc(F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H13 compound treatment 51920.0 -10800.0 -0.63 38080.0 -14100.0 -1.07 -1.1985 -0.9677 3179226 Maybridge4_000871 Cc1ccc(NC(=S)N(CCC#N)C2CCCCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H14 compound treatment 55040.0 -7700.0 -0.45 40040.0 -12200.0 -0.92 -0.9658 -0.9447 3062616 Maybridge4_000872 COC(=O)c1cc2c(nn(C)c2s1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H15 compound treatment 50440.0 -12300.0 -0.71 40000.0 -12200.0 -0.92 -1.1564 -0.9918 3179227 Maybridge4_000873 COc1ccc(cc1)c2c(N)nc(nc2SC)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H16 compound treatment 61280.0 -1460.0 -0.08 45520.0 -6670.0 -0.51 -0.4169 -0.8139 3179228 Maybridge4_000874 CC(=O)N(c1ccc(cc1)C(F)(F)F)S(=O)(=O)c2ccc(cc2)N3C(=O)CCC3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H17 compound treatment 120960.0 58200.0 3.37 95920.0 43700.0 3.31 4.7257 1.0 1612694 Maybridge4_000875 Nc1nc2Oc3ccc(Br)cc3C4C(C#N)C(O)(Nc(c1C#N)c42)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H18 compound treatment 62440.0 -296.0 -0.02 48880.0 -3310.0 -0.25 -0.1895 -0.7537 1678485 Maybridge4_000876 Cn1nccc1NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H19 compound treatment 55200.0 -7540.0 -0.44 39720.0 -12500.0 -0.94 -0.9764 -0.9386 3062617 Maybridge4_000877 CC(C)/N=C/c1ccc(cc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H20 compound treatment 62000.0 -736.0 -0.04 53720.0 1530.0 0.12 0.0515 0.4184 3179229 Maybridge4_000878 Cn1nccc1NC(=O)/C=C/C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H21 compound treatment 65320.0 2580.0 0.15 50800.0 -1390.0 -0.11 0.0313 0.1707 3062618 Maybridge4_000879 Cn1ccc(NC(=O)NC(=O)c2c(F)cccc2F)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H22 compound treatment 49920.0 -12800.0 -0.74 38800.0 -13400.0 -1.01 -1.2419 -0.9883 1656689 Maybridge4_000880 OCCNc1ncnc2sc3CCCCc3c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H23 mock treatment 68400.0 5660.0 0.33 56440.0 4250.0 0.32 0.4593 0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 H24 mock treatment 61640.0 -1100.0 -0.06 46680.0 -5510.0 -0.42 -0.34 -0.8054 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I01 compound treatment 37640.0 -25100.0 -1.45 27160.0 -25000.0 -1.89 -2.3681 -0.9914 3062619 Maybridge4_000881 Cc1n[nH]c(C)c1Cc2c(F)cccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I02 compound treatment 58600.0 -4140.0 -0.24 52840.0 646.0 0.05 -0.1349 -0.5514 1705532 Maybridge4_000882 O=C(Nc1ccccc1)N2CCCC2c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I03 compound treatment 47560.0 -15200.0 -0.88 37680.0 -14500.0 -1.1 -1.3986 -0.9939 3062620 Maybridge4_000883 Nc1ccccc1C2C=NNC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I04 compound treatment 52600.0 -10100.0 -0.59 42160.0 -10000.0 -0.76 -0.9523 -0.9919 3179230 Maybridge4_000884 Fc1c(COC(=O)c2ccccc2)cccc1COC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I05 compound treatment 26000.0 -36700.0 -2.13 20320.0 -31900.0 -2.41 -3.211 -0.998 3062621 Maybridge4_000885 CSC(=S)N(C)/N=C/c1cc(Cl)cc(Cl)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I06 compound treatment 52040.0 -10700.0 -0.62 41480.0 -10700.0 -0.81 -1.0116 -0.9912 3179231 Maybridge4_000886 Cc1nc(NC(=N)NC(=O)Nc2ccc(Cl)cc2)sc1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I07 compound treatment 59720.0 -3020.0 -0.17 50760.0 -1430.0 -0.11 -0.2003 -0.9737 3062622 Maybridge4_000887 Fc1ccccc1C(=O)Oc2ccc(Cl)c(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I08 compound treatment 63280.0 544.0 0.03 46760.0 -5430.0 -0.41 -0.2686 -0.651 3179232 Maybridge4_000888 Clc1ccc(cc1)S(=O)(=O)N(Cc2ccccc2)S(=O)(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I09 compound treatment 51360.0 -11400.0 -0.66 39120.0 -13100.0 -0.99 -1.1658 -0.9805 1166421 Maybridge4_000889 Fc1cc(CSc2nc3ccccc3s2)c4OCOCc4c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I10 compound treatment 54640.0 -8100.0 -0.47 42400.0 -9790.0 -0.74 -0.8559 -0.9756 1473503 Maybridge4_000890 OC(=O)C1(CN(CCc2ccc(Cl)cc2)CN(CCc3ccc(Cl)cc3)C1)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I11 compound treatment 47680.0 -15100.0 -0.87 40440.0 -11800.0 -0.89 -1.2459 -1.0 3179233 Maybridge4_000891 FC(F)(F)c1cc(NC(=O)C2(CC3CC4CC(C3)C2)C4)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I12 compound treatment 50240.0 -12500.0 -0.72 41400.0 -10800.0 -0.82 -1.0897 -0.9982 3062667 Maybridge4_000892 COc1cccc(OC)c1SC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I13 compound treatment 50720.0 -12000.0 -0.7 42160.0 -10000.0 -0.76 -1.0293 -0.9991 3062668 Maybridge4_000893 C/C(=N\O)/Cc1ncn(n1)c2cc(C)on2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I14 compound treatment 62320.0 -416.0 -0.02 46880.0 -5310.0 -0.4 -0.3015 -0.7482 3179234 Maybridge4_000894 Clc1ccc(/C=N/N2CCOCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I15 compound treatment 52920.0 -9820.0 -0.57 45600.0 -6590.0 -0.5 -0.7551 -0.9979 3062670 Maybridge4_000895 OCCCc1cc(n[nH]1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I16 compound treatment 61720.0 -1020.0 -0.06 43800.0 -8390.0 -0.64 -0.4909 -0.7693 3179329 Maybridge4_000896 O=C(CC#N)Nc1ccncc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I17 compound treatment 42600.0 -20100.0 -1.17 37840.0 -14400.0 -1.09 -1.5932 -0.9994 3062671 Maybridge4_000897 CN(C)/C=C/C(=O)c1nnn(c1C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I18 compound treatment 53240.0 -9500.0 -0.55 42800.0 -9390.0 -0.71 -0.8918 -0.992 1670735 Maybridge4_000898 OCCn1nc(c2ccc(F)cc2)c3ccccc3c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I19 compound treatment 57360.0 -5380.0 -0.31 45600.0 -6590.0 -0.5 -0.5732 -0.9742 3179330 Maybridge4_000899 Cc1onc(c1NC(=O)NC2CCSC2)c3c(Cl)cccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I20 compound treatment 35000.0 -27700.0 -1.61 31000.0 -21200.0 -1.6 -2.2707 -1.0 3062672 Maybridge4_000900 CSC1=NNC(N1)c2ccc(cc2)N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I21 compound treatment 63640.0 904.0 0.05 53400.0 1210.0 0.09 0.1016 0.9652 3062673 Maybridge4_000901 CSc1nc(/N=C/N(C)C)nn1CCC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I22 compound treatment 39880.0 -22900.0 -1.32 32760.0 -19400.0 -1.47 -1.9765 -0.9986 1639939 Maybridge4_000902 Cc1ccc(cc1)S(=O)(=O)N2C(Oc3ccccc23)c4ccc(Cl)c(Cl)c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I23 mock treatment 65120.0 2380.0 0.14 53000.0 806.0 0.06 0.1408 0.9326 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 I24 mock treatment 61640.0 -1100.0 -0.06 51880.0 -314.0 -0.02 -0.0617 -0.91 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J01 compound treatment 51920.0 -10800.0 -0.63 44200.0 -7990.0 -0.61 -0.871 -0.9998 3062674 Maybridge4_000903 CCN1CNC(=NC1)SCc2cccc(C#N)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J02 compound treatment 58520.0 -4220.0 -0.24 46560.0 -5630.0 -0.43 -0.4743 -0.965 3179331 Maybridge4_000904 CCCc1c(cnn1C)C(=O)Nc2cc(F)ccc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J03 compound treatment 55680.0 -7060.0 -0.41 50840.0 -1350.0 -0.1 -0.3615 -0.8578 3179332 Maybridge4_000905 CC(O)CN1CNC(=NC1)SCc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J04 compound treatment 65840.0 3100.0 0.18 48760.0 -3430.0 -0.26 -0.0566 -0.1792 3062676 Maybridge4_000906 COC(=O)c1sc(cc1NC(=O)C(F)(F)F)c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J05 compound treatment 57080.0 -5660.0 -0.33 42680.0 -9510.0 -0.72 -0.7409 -0.9365 3179333 Maybridge4_000907 OCCN1CNC(=NC1)SCc2ccc(Cl)c(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J06 compound treatment 51200.0 -11500.0 -0.67 42560.0 -9630.0 -0.73 -0.9883 -0.9991 3062677 Maybridge4_000908 COC(=O)c1scc(C)c1S(=O)(=O)Nc2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J07 compound treatment 14920.0 -47800.0 -2.77 17120.0 -35100.0 -2.65 -3.8362 -0.9998 1718232 Maybridge4_000909 O=c1n2CCN(Cc3ccccc3)c2nc4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J08 compound treatment 61480.0 -1260.0 -0.07 54440.0 2250.0 0.17 0.0688 0.3718 3062678 Maybridge4_000910 CCOC(=O)c1c[nH]c(=S)nc1C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J09 compound treatment 52000.0 -10700.0 -0.62 47640.0 -4550.0 -0.34 -0.6836 -0.9612 3179334 Maybridge4_000911 Cc1cc2ccccc2c(/N=C/c3cc(Br)cc(Br)c3O)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J10 compound treatment 46440.0 -16300.0 -0.94 34760.0 -17400.0 -1.32 -1.6008 -0.9865 1179240 Maybridge4_000912 COc1ccc(cc1)c2cc(N)nc(N)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J11 compound treatment 51280.0 -11500.0 -0.66 49840.0 -2350.0 -0.18 -0.5953 -0.8662 1730849 Maybridge4_000913 Cc1ccc(cc1)S(=O)(=O)N(CCC#N)CC2CCCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J12 compound treatment 39960.0 -22800.0 -1.32 36640.0 -15600.0 -1.18 -1.7656 -0.9984 3062679 Maybridge4_000914 COC(=O)c1cnc(Nc2ccccc2)nc1C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J13 compound treatment 39920.0 -22800.0 -1.32 26320.0 -25900.0 -1.96 -2.3196 -0.9817 3179335 Maybridge4_000915 CC(C)c1ccc(NC(=S)Nc2cccc(c2)C(F)(F)F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J14 compound treatment 33000.0 -29700.0 -1.72 30280.0 -21900.0 -1.66 -2.3912 -0.9998 1398467 Maybridge4_000916 COC(=O)c1sccc1S(=O)(=O)N2CCN(CC2)c3ncnc4c(C)csc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J15 compound treatment 57320.0 -5420.0 -0.31 44680.0 -7510.0 -0.57 -0.6241 -0.9607 3062680 Maybridge4_000917 COC(=O)c1ccc(/N=C/N(C)C)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J16 compound treatment 56200.0 -6540.0 -0.38 44400.0 -7790.0 -0.59 -0.6849 -0.977 1273229 Maybridge4_000918 COC(=O)c1ccsc1N2C(=O)c3ccccc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J17 compound treatment 1560.0 -61200.0 -3.54 1600.0 -50600.0 -3.83 -5.2143 -0.9993 1150677 Maybridge4_000919 COc1ccc2Oc3nc(N)c(C#N)c(N)c3C(C(C#N)C#N)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J18 compound treatment 36520.0 -26200.0 -1.52 28000.0 -24200.0 -1.83 -2.369 -0.9957 3179336 Maybridge4_000920 COC(=O)c1sccc1Oc2ccc(cc2NC(=O)c3ccccc3OC)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J19 compound treatment 46760.0 -16000.0 -0.93 34840.0 -17400.0 -1.31 -1.5834 -0.9853 3062681 Maybridge4_000921 C1CC1/N=C/c2ccc(cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J20 compound treatment 52160.0 -10600.0 -0.61 43440.0 -8750.0 -0.66 -0.9018 -0.9992 1209715 Maybridge4_000922 COc1cc(C(=O)NN)c(cc1OC)n2c(C)ccc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J21 compound treatment 57560.0 -5180.0 -0.3 50640.0 -1550.0 -0.12 -0.2952 -0.9165 3179337 Maybridge4_000923 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)Nc2ccsc2C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J22 compound treatment 62720.0 -16.3 0.0 46880.0 -5310.0 -0.4 -0.2851 -0.7088 3062682 Maybridge4_000924 Cn1nccc1NC(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J23 mock treatment 56640.0 -6100.0 -0.35 44720.0 -7470.0 -0.57 -0.6498 -0.9743 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 J24 mock treatment 54360.0 -8380.0 -0.49 49040.0 -3150.0 -0.24 -0.512 -0.9466 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K01 compound treatment 49760.0 -13000.0 -0.75 43560.0 -8630.0 -0.65 -0.9937 -0.9976 3179338 Maybridge4_000925 CN(C)/C=N/S(=O)(=O)c1c(C)c(C)c(C)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K02 compound treatment 22640.0 -40100.0 -2.32 18720.0 -33500.0 -2.53 -3.4343 -0.9991 1131158 Maybridge4_000926 O=S(=O)(N1CCCC1c2cccs2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K03 compound treatment 50920.0 -11800.0 -0.68 44520.0 -7670.0 -0.58 -0.8948 -0.9967 1673268 Maybridge4_000927 COc1ccc(CCn2cnn3c(=O)c4ccccc4nc3c2=O)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K04 compound treatment 37520.0 -25200.0 -1.46 28480.0 -23700.0 -1.79 -2.3023 -0.9948 3062684 Maybridge4_000928 Clc1ccc(Sc2c(C#N)cccc2C#N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K05 compound treatment 21440.0 -41300.0 -2.39 17280.0 -34900.0 -2.64 -3.5606 -0.9988 3179339 Maybridge4_000929 Cc1onc(c1C(=O)NC(=N)N2CCCC2)c3c(Cl)cccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K06 compound treatment 41960.0 -20800.0 -1.2 36480.0 -15700.0 -1.19 -1.6922 -1.0 3062686 Maybridge4_000930 NC(=O)N/C(=N\O)/CSc1ccc(Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K07 compound treatment 36520.0 -26200.0 -1.52 32520.0 -19700.0 -1.49 -2.127 -1.0 3179340 Maybridge4_000931 Clc1ccc(SCC(=N)NS(=O)(=O)c2ccc(Cl)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K08 compound treatment 37040.0 -25700.0 -1.49 29760.0 -22400.0 -1.7 -2.2535 -0.9978 3179341 Maybridge4_000932 CCN(S(=O)(=O)c1ccc(F)cc1)S(=O)(=O)c2c(C)c(C)c(C)c(C)c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K09 compound treatment 47200.0 -15500.0 -0.9 37880.0 -14300.0 -1.08 -1.4026 -0.9958 3062687 Maybridge4_000933 CS(=O)(=O)Cc1cc(F)cc2COCOc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K10 compound treatment 39440.0 -23300.0 -1.35 33480.0 -18700.0 -1.42 -1.956 -0.9997 1659719 Maybridge4_000934 Fc1cccc(Cl)c1CSC2=CC(=O)CC(C2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K11 compound treatment 25960.0 -36800.0 -2.13 11280.0 -40900.0 -3.1 -3.6965 -0.9833 3179342 Maybridge4_000935 Cc1c(C)c(C)c(C#CCOC2CCCCO2)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K12 compound treatment 49360.0 -13400.0 -0.77 41400.0 -10800.0 -0.82 -1.1257 -0.9997 3179343 Maybridge4_000936 COc1cccc(OC)c1C(=O)c2cc[n+](C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K13 compound treatment 33480.0 -29300.0 -1.7 30440.0 -21800.0 -1.65 -2.3629 -0.9999 3062688 Maybridge4_000937 N#Cc1c(oc(c1c2ccc(C#N)cc2)n3cccc3)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K14 compound treatment 34120.0 -28600.0 -1.66 35600.0 -16600.0 -1.26 -2.0605 -0.9906 3179344 Maybridge4_000938 Clc1ccc(/C=N/N2CCCCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K15 compound treatment 17000.0 -45700.0 -2.65 14080.0 -38100.0 -2.88 -3.9137 -0.9991 3062689 Maybridge4_000939 CN(C)/C=N/c1c(cnn1C)c2nc(cs2)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K16 compound treatment 33320.0 -29400.0 -1.7 31840.0 -20400.0 -1.54 -2.2945 -0.9987 1505900 Maybridge4_000940 Clc1ccc(Cl)c(c1)S(=O)(=O)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K17 compound treatment 30160.0 -32600.0 -1.89 24160.0 -28000.0 -2.12 -2.8351 -0.9983 3179345 Maybridge4_000941 CN(C1CC2CC1C=C2)C(=O)Nc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K18 compound treatment 17760.0 -45000.0 -2.61 16520.0 -35700.0 -2.7 -3.752 -0.9998 1333053 Maybridge4_000942 N1C(Nc2ccccc12)c3c[nH]c4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K19 compound treatment 47480.0 -15300.0 -0.88 41440.0 -10800.0 -0.81 -1.2006 -0.9992 3062581 Maybridge4_000943 CC(C)(C)c1cc2N=CN3CCN=C3n2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K20 compound treatment 12240.0 -50500.0 -2.93 14840.0 -37400.0 -2.83 -4.0681 -0.9999 3179346 Maybridge4_000944 CN(CCC#N)c1ccc(/C=C/2\CC/C(=C\c3ccc(cc3)N(C)CCC#N)/C2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K21 compound treatment 24800.0 -37900.0 -2.2 20440.0 -31800.0 -2.4 -3.2538 -0.999 3062583 Maybridge4_000945 CC1SCC(CS1)NC(=O)Nc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K22 compound treatment 33680.0 -29100.0 -1.68 29640.0 -22600.0 -1.71 -2.3975 -1.0 3179347 Maybridge4_000946 COc1ccc(cc1)C2Nc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K23 mock treatment 51560.0 -11200.0 -0.65 43360.0 -8830.0 -0.67 -0.9307 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 K24 mock treatment 51000.0 -11700.0 -0.68 41760.0 -10400.0 -0.79 -1.0393 -0.9972 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L01 compound treatment 39240.0 -23500.0 -1.36 29280.0 -22900.0 -1.73 -2.189 -0.9928 3062584 Maybridge4_000947 CN1CNC(=NC1)SCc2ccc(Cl)c(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L02 compound treatment 49680.0 -13100.0 -0.76 48240.0 -3950.0 -0.3 -0.7465 -0.9177 3179348 Maybridge4_000948 Cn1cc(NC(=O)Nc2ccc(cc2)C(F)(F)F)c(n1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L03 compound treatment 58680.0 -4060.0 -0.24 50160.0 -2030.0 -0.15 -0.275 -0.979 3062585 Maybridge4_000949 CN(C)/N=C(\N)/c1ccc(Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L04 compound treatment 40760.0 -22000.0 -1.27 30840.0 -21400.0 -1.62 -2.0433 -0.993 3179349 Maybridge4_000950 NC(=O)c1sc(cc1NC(=O)c2cccs2)c3ccsc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L05 compound treatment 50760.0 -12000.0 -0.69 38880.0 -13300.0 -1.01 -1.2032 -0.9834 3062586 Maybridge4_000951 CSC1=NCN(CCCO)CN1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L06 compound treatment 58720.0 -4020.0 -0.23 45120.0 -7070.0 -0.54 -0.5432 -0.9303 3179350 Maybridge4_000952 FC(F)(F)c1cc(=O)oc2cc(ccc12)N3C(=O)c4ccccc4C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L07 compound treatment 43840.0 -18900.0 -1.09 37640.0 -14600.0 -1.1 -1.5531 -1.0 3062588 Maybridge4_000953 Brc1ccc(CSC2=Nc3ccccc3C(=O)NN2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L08 compound treatment 53760.0 -8980.0 -0.52 48160.0 -4030.0 -0.31 -0.5836 -0.9678 3179351 Maybridge4_000954 COc1ccc(CC(=O)n2nc(cc2SC)c3ccc(F)cc3)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L09 compound treatment 41920.0 -20800.0 -1.21 33680.0 -18500.0 -1.4 -1.8437 -0.9972 3062590 Maybridge4_000955 COc1ccc(cc1OC)c2sc(/N=C/c3cccs3)c(C#N)c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L10 compound treatment 54520.0 -8220.0 -0.48 44360.0 -7830.0 -0.59 -0.7559 -0.9941 3179352 Maybridge4_000956 COC(=O)c1cnc(nc1C(F)(F)F)N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L11 compound treatment 50640.0 -12100.0 -0.7 47240.0 -4950.0 -0.37 -0.7607 -0.9571 1310115 Maybridge4_000957 N#CCc1ccc(NC2(CCCCC2)C#N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L12 compound treatment 45680.0 -17100.0 -0.99 42960.0 -9230.0 -0.7 -1.193 -0.9856 3062591 Maybridge4_000958 FC(F)(F)c1nc(Sc2ccc(Cl)cc2)ncc1C(=O)OCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L13 compound treatment 52600.0 -10100.0 -0.59 48200.0 -3990.0 -0.3 -0.629 -0.9523 3179450 Maybridge4_000959 CC1CN(CC(C)O1)C(=S)Nc2cccc(c2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L14 compound treatment 14240.0 -48500.0 -2.81 12200.0 -40000.0 -3.03 -4.1274 -0.9993 3179451 Maybridge4_000960 Cc1csc2c(ncnc12)N3CCN(CC3)C(=O)NC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L15 compound treatment 60360.0 -2380.0 -0.14 44120.0 -8070.0 -0.61 -0.5295 -0.8452 3062624 Maybridge4_000961 Clc1ccc2sc(Sc3ccccc3)nc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L16 compound treatment 2080.0 -60700.0 -3.51 1880.0 -50300.0 -3.81 -5.178 -0.9992 3179452 Maybridge4_000962 C(N1CCC(CC1)Nc2ncnc3sccc23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L17 compound treatment 58680.0 -4060.0 -0.24 46520.0 -5670.0 -0.43 -0.4699 -0.9597 1533957 Maybridge4_000963 CSCCC1NC(=O)NC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L18 compound treatment 54000.0 -8740.0 -0.51 43080.0 -9110.0 -0.69 -0.8457 -0.9884 3179453 Maybridge4_000964 COC(=O)c1sccc1Oc2ccc(cc2NC(=O)Nc3ccc(Cl)cc3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L19 compound treatment 52360.0 -10400.0 -0.6 41560.0 -10600.0 -0.8 -0.9943 -0.9897 3062627 Maybridge4_000965 CN(C)c1ccsc1C(=O)NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L20 compound treatment 39640.0 -23100.0 -1.34 48440.0 -3750.0 -0.28 -1.1471 -0.8386 3179454 Maybridge4_000966 COc1cc2ncnc(SCC(=O)NN)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L21 compound treatment 55200.0 -7540.0 -0.44 44960.0 -7230.0 -0.55 -0.6959 -0.9937 3062629 Maybridge4_000967 CNC(=O)c1c(C)csc1NC(=O)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L22 compound treatment 15480.0 -47300.0 -2.74 12720.0 -39500.0 -2.99 -4.0488 -0.999 1534695 Maybridge4_000968 CCN(CC)c1ncnc2sc3CCCCc3c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L23 mock treatment 62920.0 184.0 0.01 50640.0 -1550.0 -0.12 -0.0756 -0.6405 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 L24 mock treatment 55200.0 -7540.0 -0.44 50480.0 -1710.0 -0.13 -0.4005 -0.8792 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M01 compound treatment 69840.0 7100.0 0.41 53360.0 1170.0 0.09 0.3534 0.8397 3062631 Maybridge4_000969 COc1ccc(OC)c(c1)S(=O)(=O)/N=C/N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M02 compound treatment 50920.0 -11800.0 -0.68 45360.0 -6830.0 -0.52 -0.8499 -0.9904 3179455 Maybridge4_000970 Cc1nn(C)c2SC(=NS(=O)(=O)c12)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M03 compound treatment 56000.0 -6740.0 -0.39 46320.0 -5870.0 -0.44 -0.5904 -0.9979 3062632 Maybridge4_000971 Cn1c(S)nnc1C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M04 compound treatment 48800.0 -13900.0 -0.81 41280.0 -10900.0 -0.83 -1.1551 -0.9999 3179456 Maybridge4_000972 FC(F)(F)c1ccc(CNC(=O)c2ccc(Cl)cc2Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M05 compound treatment 41160.0 -21600.0 -1.25 29680.0 -22500.0 -1.7 -2.089 -0.9884 3062633 Maybridge4_000973 CC1CN(CC(C)O1)C(=N)NS(=O)(=O)c2ccc(Cl)c(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M06 compound treatment 19960.0 -42800.0 -2.48 16080.0 -36100.0 -2.73 -3.6854 -0.9988 1452088 Maybridge4_000974 CN(C)c1cc(oc(=O)c1Cl)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M07 compound treatment 42160.0 -20600.0 -1.19 38440.0 -13800.0 -1.04 -1.5791 -0.9977 3062634 Maybridge4_000975 Fc1cccc(Cl)c1CSC(=S)N2CCSCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M08 compound treatment 58680.0 -4060.0 -0.24 43440.0 -8750.0 -0.66 -0.6347 -0.9028 3179457 Maybridge4_000976 CN(C)/C=C/C(=O)C(c1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M09 compound treatment 48880.0 -13900.0 -0.8 43440.0 -8750.0 -0.66 -1.0362 -0.9955 3179458 Maybridge4_000977 Cc1cc(C)n(n1)C2=NCCN2S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M10 compound treatment 22960.0 -39800.0 -2.3 25240.0 -27000.0 -2.04 -3.0722 -0.9982 1473043 Maybridge4_000978 CC(NS(=O)(=O)c1ccc(Oc2cccc(Cl)c2C#N)cc1)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M11 compound treatment 43720.0 -19000.0 -1.1 33520.0 -18700.0 -1.41 -1.7786 -0.9924 3179459 Maybridge4_000979 Cc1ccc(C)n1c2ccsc2COC(=O)Nc3c(C)onc3c4c(F)cccc4Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M12 compound treatment 57880.0 -4860.0 -0.28 41160.0 -11000.0 -0.84 -0.7895 -0.8958 3062636 Maybridge4_000980 CC(=O)n1nccc1c2nccnc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M13 compound treatment 57320.0 -5420.0 -0.31 49880.0 -2310.0 -0.18 -0.3457 -0.9621 3062637 Maybridge4_000981 Cc1cc(no1)n2cnc(n2)c3cnoc3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M14 compound treatment 44400.0 -18300.0 -1.06 40600.0 -11600.0 -0.88 -1.3717 -0.9955 1215853 Maybridge4_000982 COC(=O)c1cccc(NC(=O)NC(C)C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M15 compound treatment 56280.0 -6460.0 -0.37 53040.0 846.0 0.06 -0.2192 -0.5776 1711378 Maybridge4_000983 Cn1ncc(NCCc2ccncc2)c(Cl)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M16 compound treatment 60800.0 -1940.0 -0.11 46320.0 -5870.0 -0.44 -0.3937 -0.8586 1176335 Maybridge4_000984 CC1CCN(CC1)C(=O)C(C#N)C(=S)Nc2ccc(C)cc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M17 compound treatment 39200.0 -23500.0 -1.36 26920.0 -25300.0 -1.91 -2.317 -0.9862 3179460 Maybridge4_000985 CN(C)/C=C/C(=O)c1sc(=S)n(CCc2ccc(Cl)cc2)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M18 compound treatment 53760.0 -8980.0 -0.52 43880.0 -8310.0 -0.63 -0.8127 -0.9955 1468395 Maybridge4_000986 COc1ccc(cc1OC)c2c(C)n(C)c(C)c2c3ccc(OC)c(OC)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M19 compound treatment 55280.0 -7460.0 -0.43 50040.0 -2150.0 -0.16 -0.4207 -0.9112 3179461 Maybridge4_000987 Cc1ccc(C)n1c2ccccc2C3C=NNC3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M20 compound treatment 56360.0 -6380.0 -0.37 39680.0 -12500.0 -0.95 -0.931 -0.9157 1563316 Maybridge4_000988 CNc1ccccc1C(=O)NC2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M21 compound treatment 24200.0 -38500.0 -2.23 23240.0 -29000.0 -2.19 -3.1285 -1.0 3179462 Maybridge4_000989 CC1SCC(CS1)NC(=O)c2c(C)onc2c3c(Cl)cccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M22 compound treatment 54240.0 -8500.0 -0.49 42320.0 -9870.0 -0.75 -0.8766 -0.9795 3062639 Maybridge4_000990 Cc1c(C)c(C)c(CN)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M23 mock treatment 62440.0 -296.0 -0.02 50640.0 -1550.0 -0.12 -0.0953 -0.8018 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 M24 mock treatment 58440.0 -4300.0 -0.25 44520.0 -7670.0 -0.58 -0.5867 -0.9285 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N01 compound treatment 47480.0 -15300.0 -0.88 39120.0 -13100.0 -0.99 -1.3248 -0.9984 3062690 Maybridge4_000991 CSC1=NCCCN1C(=O)c2ccccc2I 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N02 compound treatment 60400.0 -2340.0 -0.14 47520.0 -4670.0 -0.35 -0.3459 -0.9131 3179463 Maybridge4_000992 CCOC(=O)c1cn(CC(=O)NN)nc1C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N03 compound treatment 35840.0 -26900.0 -1.56 28880.0 -23300.0 -1.76 -2.3497 -0.9981 3062691 Maybridge4_000993 CC(C)(C)N1CNC(=NC1)SCc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N04 compound treatment 34400.0 -28300.0 -1.64 29160.0 -23000.0 -1.74 -2.3937 -0.9995 3179464 Maybridge4_000994 NC(=O)c1sc(cc1NC(=O)/C=C/c2ccsc2)c3ccsc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N05 compound treatment 20320.0 -42400.0 -2.46 14120.0 -38100.0 -2.88 -3.7756 -0.9969 3179465 Maybridge4_000995 COc1cc(/C=N/N(C)C(=S)Nc2cccc(Cl)c2C)cc(OC)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N06 compound treatment 18800.0 -43900.0 -2.55 18640.0 -33600.0 -2.54 -3.5959 -1.0 3062692 Maybridge4_000996 FC(F)(F)c1c(cnn1c2ccccc2)C(=O)Sc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N07 compound treatment 52080.0 -10700.0 -0.62 43880.0 -8310.0 -0.63 -0.8816 -1.0 3179466 Maybridge4_000997 Cc1ccc2N(CCCc2c1)C(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N08 compound treatment 45920.0 -16800.0 -0.97 34720.0 -17500.0 -1.32 -1.6242 -0.9887 1622973 Maybridge4_000998 CC1CN(CC(C)O1)c2ncnc3c(C)csc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N09 compound treatment 44240.0 -18500.0 -1.07 37880.0 -14300.0 -1.08 -1.5239 -1.0 1148536 Maybridge4_000999 COc1cc(cc(OC)c1OC)C(=O)N2CCCN3C2c4ccccc4C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N10 compound treatment 27320.0 -35400.0 -2.05 20520.0 -31700.0 -2.4 -3.1462 -0.997 3062693 Maybridge4_001000 COC(=O)c1c(C)sc2cc(sc12)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N11 compound treatment 49240.0 -13500.0 -0.78 41760.0 -10400.0 -0.79 -1.1114 -1.0 1697786 Maybridge4_001001 COc1cc(cc(OC)c1OC)C(=O)N(CCC#N)C2CC(C)CC(C)(C)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N12 compound treatment 13440.0 -49300.0 -2.86 14600.0 -37600.0 -2.85 -4.0317 -1.0 3062695 Maybridge4_001002 CC1CN(CC(C)O1)c2ncc(C(=O)OCC3CC3)c(n2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N13 compound treatment 49400.0 -13300.0 -0.77 36640.0 -15600.0 -1.18 -1.3789 -0.9791 3179467 Maybridge4_001003 CC1CN(CC(C)O1)C(=S)Nc2c(C)cccc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N14 compound treatment 3360.0 -59400.0 -3.44 1800.0 -50400.0 -3.81 -5.1298 -0.9987 3179468 Maybridge4_001004 Cc1csc2ncnc(N3CCN(CC3)C(=O)Nc4ccc(OC(F)(F)F)cc4)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N15 compound treatment 29560.0 -33200.0 -1.92 34520.0 -17700.0 -1.34 -2.3051 -0.9843 3062698 Maybridge4_001005 CN(C)C(=O)Oc1ccc2nnc3ccnn3c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N16 compound treatment 11760.0 -51000.0 -2.95 11840.0 -40400.0 -3.05 -4.2483 -0.9999 1412351 Maybridge4_001006 C1CCN(C1)c2ncnc3sccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N17 compound treatment 50000.0 -12700.0 -0.74 43560.0 -8630.0 -0.65 -0.9839 -0.9982 3179469 Maybridge4_001007 CC(C)CC1NC(=O)N(C)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N18 compound treatment 49360.0 -13400.0 -0.77 44640.0 -7550.0 -0.57 -0.9523 -0.9888 1428548 Maybridge4_001008 Cn1nccc1N2C(=O)c3ccccc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N19 compound treatment 8560.0 -54200.0 -3.14 8480.0 -43700.0 -3.31 -4.5592 -0.9997 3179470 Maybridge4_001009 C/C(=N\O)/CSC(=O)c1c(C)onc1c2c(F)cccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N20 compound treatment 49160.0 -13600.0 -0.79 43000.0 -9190.0 -0.7 -1.0483 -0.9981 3062700 Maybridge4_001010 CNC(=S)NCc1ccco1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N21 compound treatment 47160.0 -15600.0 -0.9 39880.0 -12300.0 -0.93 -1.2972 -0.9999 3179471 Maybridge4_001011 Cn1ccc(NC(=O)Nc2ccccc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N22 compound treatment 38640.0 -24100.0 -1.4 30640.0 -21600.0 -1.63 -2.1408 -0.997 1103188 Maybridge4_001012 C(CNc1ncnc2sc3CCCCc3c12)CN4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N23 mock treatment 49120.0 -13600.0 -0.79 42560.0 -9630.0 -0.73 -1.0735 -0.9992 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 N24 mock treatment 54200.0 -8540.0 -0.49 45960.0 -6230.0 -0.47 -0.6834 -0.9997 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O01 compound treatment 65120.0 2380.0 0.14 58600.0 6410.0 0.48 0.4405 0.8738 3062702 Maybridge4_001013 CN(C)/C=N/S(=O)(=O)c1ccc(Cl)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O02 compound treatment 1160.0 -61600.0 -3.57 1040.0 -51200.0 -3.87 -5.2606 -0.9992 3179472 Maybridge4_001014 Cc1nn(C)c2SC(=NS(=O)(=O)c12)SCc3c(F)cccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O03 compound treatment 59640.0 -3100.0 -0.18 51440.0 -754.0 -0.06 -0.1672 -0.8882 3062703 Maybridge4_001015 CN(C)/C=C/C(=O)c1cc(F)ccc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O04 compound treatment 62320.0 -416.0 -0.02 48040.0 -4150.0 -0.31 -0.2394 -0.7591 3179473 Maybridge4_001016 FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)OC2CCSC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O05 compound treatment 56680.0 -6060.0 -0.35 51400.0 -794.0 -0.06 -0.2906 -0.8163 3062704 Maybridge4_001017 CC1CN(CC(C)O1)C(=N)NS(=O)(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O06 compound treatment 36960.0 -25800.0 -1.49 29240.0 -23000.0 -1.74 -2.2846 -0.9972 3179474 Maybridge4_001018 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)c2ccn[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O07 compound treatment 57200.0 -5540.0 -0.32 42760.0 -9430.0 -0.71 -0.7317 -0.9348 3179571 Maybridge4_001019 Fc1cccc(Cl)c1CCNC(=O)NC(=O)Cc2c(F)cccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O08 compound treatment 44880.0 -17900.0 -1.03 39960.0 -12200.0 -0.93 -1.3863 -0.9985 3062705 Maybridge4_001020 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)S(=O)(=O)n2cccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O09 compound treatment 19160.0 -43600.0 -2.52 19400.0 -32800.0 -2.48 -3.5405 -1.0 3179572 Maybridge4_001021 CS/C(=N/S(=O)(=O)c1ccccc1)/NCCc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O10 compound treatment 43960.0 -18800.0 -1.09 38880.0 -13300.0 -1.01 -1.4818 -0.9993 1316388 Maybridge4_001022 Clc1ccc(cc1)S(=O)(=O)NCC2CN(Cc3ccccc3)CN(Cc4ccccc4)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O11 compound treatment 45800.0 -16900.0 -0.98 39080.0 -13100.0 -0.99 -1.3957 -1.0 1687690 Maybridge4_001023 Clc1cc(Cl)cc(OC(=O)C2(CC3CC4CC(C3)C2)C4)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O12 compound treatment 46560.0 -16200.0 -0.94 36160.0 -16000.0 -1.21 -1.5209 -0.9918 3063461 Maybridge4_001024 Cc1nc(CSCc2ccc(Cl)cc2Cl)cs1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O13 compound treatment 47800.0 -14900.0 -0.87 37960.0 -14200.0 -1.08 -1.3738 -0.9941 1553397 Maybridge4_001025 O=C(Nc1ccccc1)OC(CSc2ccccn2)CSc3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O14 compound treatment 30120.0 -32600.0 -1.89 27240.0 -25000.0 -1.89 -2.6719 -1.0 1170892 Maybridge4_001026 COC(=O)c1cccc(NC(=O)Nc2ccccc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O15 compound treatment 33320.0 -29400.0 -1.7 33920.0 -18300.0 -1.38 -2.1832 -0.9946 1387636 Maybridge4_001027 CN(C)c1cccc(N(C)C)c1CNS(=O)(=O)c2cc(C)c(Cl)cc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O16 compound treatment 16920.0 -45800.0 -2.65 16280.0 -35900.0 -2.72 -3.7993 -0.9999 1136580 Maybridge4_001028 Clc1ccccc1NC(=S)C(C#N)C(=O)N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O17 compound treatment 60160.0 -2580.0 -0.15 50080.0 -2110.0 -0.16 -0.2187 -0.9994 3063462 Maybridge4_001029 CN(C1CC2CC1C=C2)S(=O)(=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O18 compound treatment 52120.0 -10600.0 -0.62 42400.0 -9790.0 -0.74 -0.9591 -0.9957 1238489 Maybridge4_001030 Cc1cc2NC(=O)c3ccccc3C(=Nc2cc1C)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O19 compound treatment 61640.0 -1100.0 -0.06 41360.0 -10800.0 -0.82 -0.6248 -0.7596 3063463 Maybridge4_001031 CN(C)/C=N/c1ccccc1C2C=NNC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O20 compound treatment 62560.0 -176.0 -0.01 51320.0 -874.0 -0.07 -0.054 -0.8067 3179573 Maybridge4_001032 S=C1NCCN1Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O21 compound treatment 56800.0 -5940.0 -0.34 49680.0 -2510.0 -0.19 -0.3777 -0.961 1607454 Maybridge4_001033 CC1=C(N2CCOCC2)C(=NCCN1)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O22 compound treatment 60520.0 -2220.0 -0.13 49840.0 -2350.0 -0.18 -0.2168 -0.9871 1293246 Maybridge4_001034 Cc1nc2ccccc2n1C3CC(=O)N(C3=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O23 mock treatment 59440.0 -3300.0 -0.19 54240.0 2050.0 0.15 -0.0255 -0.1038 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 O24 mock treatment 67480.0 4740.0 0.27 57280.0 5090.0 0.39 0.4666 0.9863 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P01 compound treatment 63800.0 1060.0 0.06 57320.0 5130.0 0.39 0.318 0.8093 1354193 Maybridge4_001035 OCCN1CNC(=S)NC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P02 compound treatment 1040.0 -61700.0 -3.57 960.0 -51200.0 -3.88 -5.2698 -0.9992 3179574 Maybridge4_001036 FC(F)(F)c1cc(NC(=O)N/C=C/c2ccsc2)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P03 compound treatment 51920.0 -10800.0 -0.63 37920.0 -14300.0 -1.08 -1.2071 -0.9664 3063464 Maybridge4_001037 C(SC1=NCN(Cc2ccccc2)CN1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P04 compound treatment 1640.0 -61100.0 -3.54 1440.0 -50800.0 -3.84 -5.2195 -0.9992 3179575 Maybridge4_001038 COC(=O)c1sccc1N2C(=O)C=C(C)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P05 compound treatment 21000.0 -41700.0 -2.42 16960.0 -35200.0 -2.67 -3.5957 -0.9988 3179576 Maybridge4_001039 CN(/N=C/c1ccccn1)C(=S)Nc2ccc(C)c(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P06 compound treatment 36280.0 -26500.0 -1.53 28400.0 -23800.0 -1.8 -2.3574 -0.9968 1429512 Maybridge4_001040 CCCc1c(NC(=O)Nc2ccc(Cl)cc2Cl)cnn1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P07 compound treatment 52280.0 -10500.0 -0.61 38760.0 -13400.0 -1.02 -1.1474 -0.9694 1160255 Maybridge4_001041 N#CC1(CCCCCC1)NC(Cc2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P08 compound treatment 6960.0 -55800.0 -3.23 4960.0 -47200.0 -3.58 -4.8132 -0.9987 1344462 Maybridge4_001042 CC(C)Nc1ncnc2c(C)csc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P09 compound treatment 50200.0 -12500.0 -0.73 44640.0 -7550.0 -0.57 -0.9179 -0.993 3179577 Maybridge4_001043 COc1cc(cc(OC)c1OC)C2NN=C3C2N4CCC3CC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P10 compound treatment 41760.0 -21000.0 -1.22 39800.0 -12400.0 -0.94 -1.5227 -0.9918 3063465 Maybridge4_001044 FC(F)(F)c1ccc(NC(=O)C2CCc3ccccc3O2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P11 compound treatment 49560.0 -13200.0 -0.76 43360.0 -8830.0 -0.67 -1.0126 -0.9978 1463450 Maybridge4_001045 COc1cc(cc(OC)c1OC)C(=O)N(CCC#N)Cc2ccncc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P12 compound treatment 31000.0 -31700.0 -1.84 28520.0 -23700.0 -1.79 -2.5673 -0.9999 3179578 Maybridge4_001046 CSc1cc(nn1S(=O)(=O)c2cccc(c2)C(F)(F)F)c3ccc(F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P13 compound treatment 42280.0 -20500.0 -1.19 34400.0 -17800.0 -1.35 -1.7904 -0.998 3063466 Maybridge4_001047 COc1cccc(NC(=S)N(CCC#N)/N=C/c2ccc3OCOc3c2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P14 compound treatment 1600.0 -61100.0 -3.54 1760.0 -50400.0 -3.82 -5.2041 -0.9993 1234970 Maybridge4_001048 Cc1csc2ncnc(N3CCN(CC3)C(=S)Nc4ccc(F)cc4F)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P15 compound treatment 41600.0 -21100.0 -1.22 38120.0 -14100.0 -1.07 -1.6192 -0.9976 1069786 Maybridge4_001049 NNC(=O)OC1(CC2CC3CC(C2)C1)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P16 compound treatment 46560.0 -16200.0 -0.94 30280.0 -21900.0 -1.66 -1.8356 -0.9635 3179579 Maybridge4_001050 CCOC(=O)c1cnc(Sc2ccc(F)c(Cl)c2)nc1C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P17 compound treatment 58280.0 -4460.0 -0.26 41280.0 -10900.0 -0.83 -0.7667 -0.8858 3063467 Maybridge4_001051 Sc1nc(ccc1C#N)c2ccc3OCCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P18 compound treatment 46600.0 -16100.0 -0.93 44440.0 -7750.0 -0.59 -1.0761 -0.9748 1377109 Maybridge4_001052 CCOC(=O)c1cc(=O)c2cc(Cl)ccc2o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P19 compound treatment 45440.0 -17300.0 -1.0 42960.0 -9230.0 -0.7 -1.2028 -0.9845 1695486 Maybridge4_001053 CC1CCCN(C1)c2ccc3nncn3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P20 compound treatment 6920.0 -55800.0 -3.23 5000.0 -47200.0 -3.57 -4.8127 -0.9988 3063468 Maybridge4_001054 Cn1ncc(Br)c1NC(=O)CSc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P21 compound treatment 42800.0 -19900.0 -1.16 37040.0 -15200.0 -1.15 -1.6278 -1.0 3179580 Maybridge4_001055 COC(=O)c1sccc1NS(=O)(=O)c2ccc(F)cc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P22 compound treatment 32000.0 -30700.0 -1.78 26320.0 -25900.0 -1.96 -2.6441 -0.9989 1127720 Maybridge4_001056 CCC(C)Nc1ncnc2cc(OC)c(OC)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P23 mock treatment 47280.0 -15500.0 -0.9 42160.0 -10000.0 -0.76 -1.1703 -0.9966 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2051 P24 mock treatment 60160.0 -2580.0 -0.15 48920.0 -3270.0 -0.25 -0.2808 -0.9706 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A01 compound treatment 59280.0 9390.0 0.54 63240.0 11200.0 0.85 0.9863 0.9767 1118682 Maybridge4_001057 Cc1cc(NS(=O)(=O)c2ccc(NC(=O)c3ccco3)cc2)no1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A02 compound treatment 22760.0 -27100.0 -1.57 36840.0 -15200.0 -1.15 -1.9229 -0.9881 1260001 Maybridge4_001058 O=C(CC1(CC2CC3CC(C2)C1)C3)NC4CCN(Cc5ccccc5)CC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A03 compound treatment 32320.0 -17600.0 -1.02 39040.0 -13000.0 -0.98 -1.4135 -0.9998 3063469 Maybridge4_001059 Cn1ncc(C(=O)Sc2ccc(Cl)cc2)c1n3cccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A04 compound treatment 58120.0 8230.0 0.48 54880.0 2880.0 0.22 0.4913 0.9369 3179581 Maybridge4_001060 Oc1cc(nc(SCC(=O)c2ccc(Cl)s2)n1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A05 compound treatment 5520.0 -44400.0 -2.57 4960.0 -47000.0 -3.56 -4.3356 -0.9872 3063470 Maybridge4_001061 FC(F)(F)c1ccnc(Sc2ccccc2NC(=O)Nc3ccccc3)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A06 compound treatment 31160.0 -18700.0 -1.08 35480.0 -16500.0 -1.25 -1.6516 -0.9975 3179582 Maybridge4_001062 CC(C)(C)c1cc(C(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F)n(Cc4ccc(F)cc4)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A07 compound treatment 39280.0 -10600.0 -0.61 50600.0 -1400.0 -0.11 -0.5097 -0.8172 3063471 Maybridge4_001063 CN(/N=C/c1ncc(cc1Cl)C(F)(F)F)C(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A08 compound treatment 49360.0 -526.0 -0.03 56720.0 4720.0 0.36 0.2309 0.6444 3179583 Maybridge4_001064 COC(=O)c1ccc(n1C)S(=O)(=O)NCCNc2cccc(n2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A09 compound treatment 46880.0 -3010.0 -0.17 52080.0 76.3 0.01 -0.1191 -0.6833 3063472 Maybridge4_001065 Cc1cccc(c1)n2c(CC#N)n[nH]c2=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A10 compound treatment 6680.0 -43200.0 -2.5 8560.0 -43400.0 -3.29 -4.0954 -0.9909 1646442 Maybridge4_001066 Cc1ccc2N(CC(=O)N(C3CCCCC3)c4ccccc4)CCCc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A11 compound treatment 34760.0 -15100.0 -0.88 33840.0 -18200.0 -1.37 -1.5919 -0.9763 1595838 Maybridge4_001067 COC(=O)c1sccc1S(=O)(=O)Nc2cc(OC)c(OC)cc2C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A12 compound treatment 56480.0 6590.0 0.38 58560.0 6560.0 0.5 0.6211 0.9916 3179584 Maybridge4_001068 FC(F)(F)c1ccc(N2CCc3ccccc3C2)c(NC(=O)c4ccccc4)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A13 compound treatment 46120.0 -3770.0 -0.22 48600.0 -3400.0 -0.26 -0.3365 -0.9966 3063473 Maybridge4_001069 FC(F)(F)C1=NCCN(C=C1)S(=O)(=O)c2ccc(CNC(=O)c3ccccc3)s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A14 compound treatment 50680.0 794.0 0.05 53280.0 1280.0 0.1 0.1008 0.9424 1536339 Maybridge4_001070 OC(=O)COCC(=O)N1CCCN(CC1)c2nc3ccc(Cl)cc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A15 compound treatment 36600.0 -13300.0 -0.77 33600.0 -18400.0 -1.39 -1.5294 -0.9609 1391994 Maybridge4_001071 CCOC(=O)C1CCN(CC1)c2ncnc3cc(OC)c(OC)cc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A16 compound treatment 22920.0 -27000.0 -1.56 28640.0 -23400.0 -1.77 -2.3553 -0.9981 1501197 Maybridge4_001072 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)NCC3CCN(CC3)C(=O)OC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A17 compound treatment 50400.0 514.0 0.03 52960.0 956.0 0.07 0.0722 0.9229 1440783 Maybridge4_001073 COc1cc(cc(OC)c1OC)C(CC(=O)O)CC(=O)N2CCC(CC2)n3cccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A18 compound treatment 3680.0 -46200.0 -2.68 3640.0 -48400.0 -3.66 -4.4816 -0.9882 1175173 Maybridge4_001074 CC(C)(C)c1ccc(cc1)c2noc(n2)c3ccc4OCCc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A19 compound treatment 52320.0 2430.0 0.14 56200.0 4200.0 0.32 0.3243 0.9332 1213784 Maybridge4_001075 NC(=O)C1CCN(CN2C(=O)c3ccccc3C2=O)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A20 compound treatment 56200.0 6310.0 0.37 54440.0 2440.0 0.18 0.3891 0.9497 1134687 Maybridge4_001076 OC(=O)c1nccnc1C(=O)Nc2ccc(cc2)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A21 compound treatment 960.0 -48900.0 -2.83 1040.0 -51000.0 -3.86 -4.7322 -0.9885 3063474 Maybridge4_001077 FC(F)(F)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A22 compound treatment 36480.0 -13400.0 -0.78 38360.0 -13600.0 -1.03 -1.2795 -0.9901 3179585 Maybridge4_001078 COc1ccccc1N2CCN(CC2)C(=O)c3cnn(c3C)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A23 mock treatment 51080.0 1190.0 0.07 61800.0 9800.0 0.74 0.5732 0.7697 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 A24 mock treatment 61800.0 11900.0 0.69 61960.0 9960.0 0.75 1.021 0.999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B01 compound treatment 53880.0 3990.0 0.23 60680.0 8680.0 0.66 0.628 0.9019 1733246 Maybridge4_001079 Cc1cnc(cn1)C(=O)Nc2nnn[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B02 compound treatment 48320.0 -1570.0 -0.09 59840.0 7840.0 0.59 0.3553 0.592 1403239 Maybridge4_001080 NC(=O)C1CCN(CC(O)COc2ccc(cc2)c3csnn3)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B03 compound treatment 54880.0 4990.0 0.29 60720.0 8720.0 0.66 0.6711 0.9316 1480432 Maybridge4_001081 COc1ccc(cc1OC)S(=O)(=O)NCCN2CCNC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B04 compound treatment 36560.0 -13300.0 -0.77 43440.0 -8560.0 -0.65 -1.0043 -0.9962 3179682 Maybridge4_001082 Cc1ccsc1CNC(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B05 compound treatment 48120.0 -1770.0 -0.1 52840.0 836.0 0.06 -0.0276 -0.2294 1539091 Maybridge4_001083 OC(=O)c1cc(ccc1O)S(=O)(=O)NCCN2CCNC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B06 compound treatment 47120.0 -2770.0 -0.16 47160.0 -4840.0 -0.37 -0.3726 -0.9311 1590468 Maybridge4_001084 O=C(Nc1ccc(cc1)S(=O)(=O)N2CCOCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B07 compound treatment 47840.0 -2050.0 -0.12 46040.0 -5960.0 -0.45 -0.403 -0.8635 1660094 Maybridge4_001085 Cc1nn(nc1C(=O)NC2CCS(=O)(=O)C2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B08 compound treatment 42760.0 -7130.0 -0.41 45240.0 -6760.0 -0.51 -0.654 -0.9943 1742612 Maybridge4_001086 COc1ccc(SCC(=O)NCc2ccc3OCOc3c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B09 compound treatment 42800.0 -7090.0 -0.41 46240.0 -5760.0 -0.44 -0.5988 -0.9995 3179683 Maybridge4_001087 CCOC(=O)c1c(NC(=O)NC(C)(C)C)sc2CN(C)CCc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B10 compound treatment 24320.0 -25600.0 -1.48 29840.0 -22200.0 -1.68 -2.2337 -0.9981 1477333 Maybridge4_001088 Cc1cc(NC(=O)C2CCN(CC2)C(=O)OCc3ccccc3)n(C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B11 compound treatment 39400.0 -10500.0 -0.61 43720.0 -8280.0 -0.63 -0.873 -0.9999 1603040 Maybridge4_001089 O=C(N1CCN(CC1)C(c2ccccc2)c3ccccc3)c4ccc5OCCc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B12 compound treatment 40880.0 -9010.0 -0.52 46640.0 -5360.0 -0.41 -0.6561 -0.9923 3179684 Maybridge4_001090 Cn1c(SCC(=O)c2ccc3OCCOc3c2)nnc1c4ccc5ccccc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B13 compound treatment 39360.0 -10500.0 -0.61 46440.0 -5560.0 -0.42 -0.729 -0.9837 3063475 Maybridge4_001091 CN(C(=O)c1scc(c1C)S(=O)(=O)c2ccc(Cl)cc2)c3nnc(s3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B14 compound treatment 36200.0 -13700.0 -0.79 43240.0 -8760.0 -0.66 -1.0298 -0.9961 3179685 Maybridge4_001092 CCOC(=O)c1c(C)n(c(C)c1/C=C/2\C(=O)Nc3ccccc23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B15 compound treatment 54120.0 4230.0 0.25 55880.0 3880.0 0.29 0.3809 0.996 1321807 Maybridge4_001093 Cn1nc(cc1C(=O)NN2CCOCC2)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B16 compound treatment 17800.0 -32100.0 -1.86 21840.0 -30200.0 -2.28 -2.929 -0.9948 3179686 Maybridge4_001094 Cc1ccc(cc1)S(=O)(=O)CCSc2nccc(n2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B17 compound treatment 48760.0 -1130.0 -0.07 51960.0 -43.8 0.0 -0.0485 -0.742 1191907 Maybridge4_001095 O=C1NCCN1CCNC(=S)NC2CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B18 compound treatment 43560.0 -6330.0 -0.37 46840.0 -5160.0 -0.39 -0.5356 -0.9995 1709557 Maybridge4_001096 COc1ccc(OCC(O)CNC(=O)c2c(C)onc2c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B19 compound treatment 35040.0 -14800.0 -0.86 42400.0 -9600.0 -0.73 -1.1223 -0.9965 1259000 Maybridge4_001097 CCCc1c(cnn1c2ccccc2)C(=O)N(Cc3cccs3)Cc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B20 compound treatment 50640.0 754.0 0.04 59200.0 7200.0 0.54 0.4161 0.7614 1607244 Maybridge4_001098 O=C(N1CCN(CCN2CCOCC2)CC1)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B21 compound treatment 43840.0 -6050.0 -0.35 43680.0 -8320.0 -0.63 -0.6932 -0.9616 1594969 Maybridge4_001099 CCCc1c(cnn1c2ccccc2)C(=O)Nc3nc[nH]n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B22 compound treatment 39000.0 -10900.0 -0.63 37000.0 -15000.0 -1.14 -1.2491 -0.9615 3063476 Maybridge4_001100 Clc1ccc(Sc2cccc(Cl)c2Cn3cccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B23 mock treatment 57560.0 7670.0 0.44 61280.0 9280.0 0.7 0.8109 0.9757 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 B24 mock treatment 57440.0 7550.0 0.44 68320.0 16300.0 1.24 1.1828 0.9027 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C01 compound treatment 57120.0 7230.0 0.42 64360.0 12400.0 0.94 0.9577 0.9344 3179687 Maybridge4_001101 Cc1cc(NS(=O)(=O)c2ccc(cc2)N3C(=O)C=CC3=O)no1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C02 compound treatment 33280.0 -16600.0 -0.96 36320.0 -15700.0 -1.19 -1.5198 -0.9946 1404378 Maybridge4_001102 OC1(CCN(CC1)C(=O)CC2(CC3CC4CC(C3)C2)C4)c5ccc(Cl)cc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C03 compound treatment 2680.0 -47200.0 -2.74 2440.0 -49600.0 -3.75 -4.5868 -0.9879 1249628 Maybridge4_001103 COc1ccc(cc1OC)C(=O)N2CCN(CC2)c3ncnc4cc(sc34)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C04 compound treatment 37440.0 -12400.0 -0.72 44280.0 -7720.0 -0.58 -0.9233 -0.9946 3063496 Maybridge4_001104 Fc1ccc(NC(=O)NCc2nc(no2)c3ccc(cc3)C(F)(F)F)c(F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C05 compound treatment 45760.0 -4130.0 -0.24 50120.0 -1880.0 -0.14 -0.2699 -0.9695 3063497 Maybridge4_001105 OC(CSc1ccccc1NC(=O)/C=C\C(=O)O)Cn2ccc(n2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C06 compound treatment 48360.0 -1530.0 -0.09 51480.0 -524.0 -0.04 -0.0906 -0.9345 3063498 Maybridge4_001106 Cn1nc(c(c1NC(=O)c2nccnc2C(=O)O)c3cccc(c3)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C07 compound treatment 54800.0 4910.0 0.28 54320.0 2320.0 0.18 0.3253 0.9729 3179688 Maybridge4_001107 CN(/N=C/c1ncc(cc1Cl)C(F)(F)F)C(=O)Nc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C08 compound treatment 41720.0 -8170.0 -0.47 45440.0 -6560.0 -0.5 -0.6859 -0.9997 3063499 Maybridge4_001108 FC(F)(F)C1=NCCN(C=C1)C(=O)C2CCN(CC2)c3nccc(n3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C09 compound treatment 43120.0 -6770.0 -0.39 44000.0 -8000.0 -0.61 -0.7056 -0.9778 1483010 Maybridge4_001109 COc1ccc(CN(Cc2cccn2C)C(=O)c3cc4cc(OC)ccc4[nH]3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C10 compound treatment 55000.0 5110.0 0.3 51160.0 -844.0 -0.06 0.1643 0.5422 1408441 Maybridge4_001110 COC(=O)c1sc(cc1NC(=O)COCC(=O)O)c2ccc(cc2)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C11 compound treatment 35520.0 -14400.0 -0.83 35200.0 -16800.0 -1.27 -1.488 -0.9789 3179689 Maybridge4_001111 FC(F)(F)c1cc(N2CCN(CC2)C(=O)C3CCC3)c4ccccc4n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C12 compound treatment 36760.0 -13100.0 -0.76 41400.0 -10600.0 -0.8 -1.1053 -0.9996 3063500 Maybridge4_001112 FC(F)(F)c1oc(cc1C(=O)NCc2cccs2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C13 compound treatment 39960.0 -9930.0 -0.58 45440.0 -6560.0 -0.5 -0.758 -0.9973 3179690 Maybridge4_001113 CCC(=O)N(C)c1nc(cs1)c2ccc(Cl)s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C14 compound treatment 8240.0 -41600.0 -2.41 12040.0 -40000.0 -3.03 -3.8452 -0.9937 3179691 Maybridge4_001114 Fc1ccc(cc1)S(=O)(=O)Nc2ccccc2NC3CCN(Cc4ccccc4)CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C15 compound treatment 22240.0 -27600.0 -1.6 25480.0 -26500.0 -2.01 -2.5523 -0.9937 1317474 Maybridge4_001115 COc1cccc(Cl)c1NC(=O)N2CCN(CC2)c3cc(C)nc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C16 compound treatment 37400.0 -12500.0 -0.72 37240.0 -14800.0 -1.12 -1.3018 -0.9778 3179692 Maybridge4_001116 CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cccc(c2)C(F)(F)F)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C17 compound treatment 3480.0 -46400.0 -2.69 3120.0 -48900.0 -3.7 -4.5176 -0.9877 1139184 Maybridge4_001117 COc1ccc(CC2CCC3(CC2)NC(=O)c4ccccc4O3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C18 compound treatment 44600.0 -5290.0 -0.31 46560.0 -5440.0 -0.41 -0.5079 -0.9893 1486833 Maybridge4_001118 COC(=O)c1cc(oc1C)S(=O)(=O)NCC2CN(Cc3ccccc3)CN(Cc4ccccc4)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C19 compound treatment 44720.0 -5170.0 -0.3 44400.0 -7600.0 -0.58 -0.6186 -0.9536 1538683 Maybridge4_001119 OC1(CCN(CN2C(=O)c3ccccc3C2=O)CC1)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C20 compound treatment 50000.0 114.0 0.01 54080.0 2080.0 0.16 0.1158 0.7361 3063501 Maybridge4_001120 OC(=O)/C=C/C(=O)Nc1ccc(nc1N2CCOCC2)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C21 compound treatment 54040.0 4150.0 0.24 62920.0 10900.0 0.83 0.7545 0.8766 1658419 Maybridge4_001121 NC(=O)C1CCN(CC(O)CSc2ccc(F)cc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C22 compound treatment 55160.0 5270.0 0.31 57760.0 5760.0 0.44 0.5242 0.9849 1233858 Maybridge4_001122 CS(=O)(=O)CS(=O)(=O)Nc1ccc2OCCOc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C23 mock treatment 54560.0 4670.0 0.27 58840.0 6840.0 0.52 0.5574 0.9544 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 C24 mock treatment 62000.0 12100.0 0.7 60240.0 8240.0 0.62 0.9371 0.9983 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D01 compound treatment 49040.0 -846.0 -0.05 52080.0 76.3 0.01 -0.0306 -0.6196 1662148 Maybridge4_001123 Cc1nc(cn1C)S(=O)(=O)NC2CCS(=O)(=O)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D02 compound treatment 13160.0 -36700.0 -2.13 20480.0 -31500.0 -2.39 -3.1919 -0.9984 1341736 Maybridge4_001124 CCN(CC)c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D03 compound treatment 45320.0 -4570.0 -0.26 57040.0 5040.0 0.38 0.0825 0.1778 3063502 Maybridge4_001125 Cn1cnc(c1)S(=O)(=O)NCC2CCN(CC2)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D04 compound treatment 37160.0 -12700.0 -0.74 43080.0 -8920.0 -0.68 -0.999 -0.999 3179693 Maybridge4_001126 Cc1nnc(Sc2nc3ccc(Cl)cc3s2)n1c4ccc5OCCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D05 compound treatment 45280.0 -4610.0 -0.27 48760.0 -3240.0 -0.25 -0.3623 -0.9991 1259497 Maybridge4_001127 O=C1NCCN1CCNS(=O)(=O)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D06 compound treatment 44680.0 -5210.0 -0.3 46080.0 -5920.0 -0.45 -0.5304 -0.9814 1281709 Maybridge4_001128 OC(=O)CSCC(=O)N1CCN(Cc2ccc3OCOc3c2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D07 compound treatment 23240.0 -26600.0 -1.54 34600.0 -17400.0 -1.32 -2.0232 -0.9969 1146339 Maybridge4_001129 CCCCc1ccc(cc1)n2c(coc2=O)c3ccc(F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D08 compound treatment 26720.0 -23200.0 -1.34 34080.0 -17900.0 -1.36 -1.9084 -1.0 1522891 Maybridge4_001130 COC(=O)C1=C(CSC1)Nc2ccccc2NS(=O)(=O)c3cn(C)cn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D09 compound treatment 51160.0 1270.0 0.07 51280.0 -724.0 -0.05 0.0134 0.1463 3063503 Maybridge4_001131 FC(F)(F)c1nn2c(=O)cc([nH]c2c1c3ccccc3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D10 compound treatment 52240.0 2350.0 0.14 48280.0 -3720.0 -0.28 -0.1029 -0.3286 1088065 Maybridge4_001132 Cc1cc(C(=O)Nc2ccccc2)c(C)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D11 compound treatment 44640.0 -5250.0 -0.3 45560.0 -6440.0 -0.49 -0.5598 -0.9741 1383227 Maybridge4_001133 O=C(OCCn1ncc2ccccc2c1=O)c3ccc4OCCc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D12 compound treatment 38120.0 -11800.0 -0.68 36160.0 -15800.0 -1.2 -1.3301 -0.9642 1524796 Maybridge4_001134 Cc1ccc(cc1)c2cc(Cc3ccccc3)c(=O)[nH]n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D13 compound treatment 37600.0 -12300.0 -0.71 37080.0 -14900.0 -1.13 -1.3021 -0.9752 1531019 Maybridge4_001135 Cc1c(csc1C(=O)N(Cc2ccccc2)Cc3cccnc3)S(=O)(=O)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D14 compound treatment 45440.0 -4450.0 -0.26 52560.0 556.0 0.04 -0.1524 -0.5838 3063504 Maybridge4_001136 OC(=O)c1nccnc1C(=O)Nc2ccc(CC#N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D15 compound treatment 44840.0 -5050.0 -0.29 46760.0 -5240.0 -0.4 -0.4874 -0.9887 1469748 Maybridge4_001137 CSc1nsc(SC)c1C(=O)NN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D16 compound treatment 24840.0 -25000.0 -1.45 30680.0 -21300.0 -1.61 -2.1674 -0.9986 3063505 Maybridge4_001138 Fc1ccc(cc1)S(=O)(=O)CCSc2nccc(n2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D17 compound treatment 45720.0 -4170.0 -0.24 49240.0 -2760.0 -0.21 -0.3186 -0.9975 3179791 Maybridge4_001139 COC(=O)c1ccc(n1C)S(=O)(=O)Nc2ccc3COC(=O)c3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D18 compound treatment 48000.0 -1890.0 -0.11 47880.0 -4120.0 -0.31 -0.298 -0.901 3179792 Maybridge4_001140 COc1ccc(OCC(O)CNC(=O)c2ccc(OC(F)(F)F)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D19 compound treatment 42880.0 -7010.0 -0.41 51360.0 -644.0 -0.05 -0.3215 -0.7863 1658181 Maybridge4_001141 CCCc1c(cnn1c2ccccc2)C(=O)NCc3ccc4OCOc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D20 compound treatment 42880.0 -7010.0 -0.41 50920.0 -1080.0 -0.08 -0.345 -0.8332 1302806 Maybridge4_001142 CCOC(=O)N1CCC(CC1)NC(=O)Nc2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D21 compound treatment 51640.0 1750.0 0.1 55640.0 3640.0 0.28 0.2665 0.9082 1417198 Maybridge4_001143 COc1cccc2n(C)nc(NC(=O)CCC(=O)O)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D22 compound treatment 49960.0 73.8 0.0 48880.0 -3120.0 -0.24 -0.1642 -0.6942 1130087 Maybridge4_001144 COc1ccc(OCC(O)CNC(=O)Nc2ccccc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D23 mock treatment 57640.0 7750.0 0.45 62840.0 10800.0 0.82 0.8977 0.9598 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 D24 mock treatment 51360.0 1470.0 0.09 52160.0 156.0 0.01 0.0687 0.7974 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E01 compound treatment 49920.0 33.8 0.0 49640.0 -2360.0 -0.18 -0.1251 -0.6993 1356815 Maybridge4_001145 Cn1ncc2c(NN3C(=O)CCC3=O)ncnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E02 compound treatment 49720.0 -166.0 -0.01 51840.0 -164.0 -0.01 -0.0156 -0.9922 3063506 Maybridge4_001146 FC(F)(F)c1ccc(NC(=O)Nc2ccc(cc2)N3CCN(Cc4ccccc4)CC3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E03 compound treatment 45800.0 -4090.0 -0.24 51680.0 -324.0 -0.02 -0.1847 -0.7762 3179793 Maybridge4_001147 COC(=O)c1sc(cc1NS(=O)(=O)c2ccc(C)cc2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E04 compound treatment 40.0 -49800.0 -2.89 160.0 -51800.0 -3.92 -4.817 -0.9886 1593578 Maybridge4_001148 Cc1noc(C)c1n2sc(=O)n(CC3CC3)c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E05 compound treatment 22560.0 -27300.0 -1.58 24440.0 -27600.0 -2.09 -2.5948 -0.9907 1366685 Maybridge4_001149 OC(CSc1ccccc1NC(=O)c2ccc(Cl)cc2)Cn3ccc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E06 compound treatment 2280.0 -47600.0 -2.76 2280.0 -49700.0 -3.76 -4.6118 -0.9883 1718437 Maybridge4_001150 CCCCc1ccc(NC(=O)N2CCN(CC2)c3cc(C)nc4ccccc34)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E07 compound treatment 47360.0 -2530.0 -0.15 52520.0 516.0 0.04 -0.0759 -0.5008 3063507 Maybridge4_001151 CNC(=S)NC1CC2CCC1C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E08 compound treatment 26320.0 -23600.0 -1.37 23880.0 -28100.0 -2.13 -2.4708 -0.977 1663721 Maybridge4_001152 Fc1ccc(cc1Cl)n2sc(=O)n(C3Cc4ccccc4C3)c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E09 compound treatment 32200.0 -17700.0 -1.02 46960.0 -5040.0 -0.38 -0.9945 -0.9095 3063508 Maybridge4_001153 Cc1nnsc1c2nc(cs2)c3ccc(Cl)s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E10 compound treatment 40720.0 -9170.0 -0.53 44640.0 -7360.0 -0.56 -0.7697 -0.9997 1128288 Maybridge4_001154 COC(=O)c1ccc(n1C)S(=O)(=O)N(Cc2ccccc2)Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E11 compound treatment 6080.0 -43800.0 -2.54 7040.0 -45000.0 -3.4 -4.2013 -0.9896 1703913 Maybridge4_001155 CC(C)Cc1ccc(cc1)C(C)C(=O)Nc2cccc(c2)c3cnco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E12 compound treatment 3000.0 -46900.0 -2.72 3720.0 -48300.0 -3.65 -4.5052 -0.9893 1704448 Maybridge4_001156 Cc1cccc(Cl)c1n2sc(=O)n(CC3CC3)c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E13 compound treatment 32280.0 -17600.0 -1.02 42120.0 -9880.0 -0.75 -1.2503 -0.9884 1205718 Maybridge4_001157 CN(C(=O)C1CCCCC1)c2nc(cs2)c3ccc(Cl)s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E14 compound treatment 30880.0 -19000.0 -1.1 30200.0 -21800.0 -1.65 -1.9457 -0.9807 3179794 Maybridge4_001158 Cc1ccc(OCC(O)CNc2ccc(Br)c(c2)C(F)(F)F)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E15 compound treatment 47280.0 -2610.0 -0.15 58760.0 6760.0 0.51 0.2548 0.4779 3063509 Maybridge4_001159 OC(=O)c1sccc1S(=O)(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E16 compound treatment 44120.0 -5770.0 -0.33 53920.0 1920.0 0.15 -0.1337 -0.367 1390204 Maybridge4_001160 Cn1cnc(c1)S(=O)(=O)NCC2CCN(CC2)C(=O)OC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E17 compound treatment 31440.0 -18400.0 -1.07 29720.0 -22300.0 -1.69 -1.9484 -0.9758 1537127 Maybridge4_001161 COc1ccccc1NC(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E18 compound treatment 12840.0 -37000.0 -2.15 21280.0 -30700.0 -2.33 -3.1622 -0.9992 1388804 Maybridge4_001162 COc1ccc(cc1)C(=O)CN2CCCc3cc(C)ccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E19 compound treatment 35880.0 -14000.0 -0.81 41840.0 -10200.0 -0.77 -1.1178 -0.9996 1307254 Maybridge4_001163 COc1ccc(CN(Cc2cccn2C)S(=O)(=O)c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E20 compound treatment 17080.0 -32800.0 -1.9 28120.0 -23900.0 -1.81 -2.6224 -0.9997 1235221 Maybridge4_001164 Fc1cccc(Cl)c1CN2CCC(CC2)NS(=O)(=O)c3cccc4nonc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E21 compound treatment 41920.0 -7970.0 -0.46 49040.0 -2960.0 -0.22 -0.485 -0.9451 3179795 Maybridge4_001165 COC(=O)c1ccc(n1C)S(=O)(=O)N2CCN(CC2)c3ccc(cn3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E22 compound treatment 47720.0 -2170.0 -0.13 59120.0 7120.0 0.54 0.2921 0.5282 1482186 Maybridge4_001166 Cc1ccc(cc1)S(=O)(=O)NC(=O)NCC2CCN(CC2)C(=O)OC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E23 mock treatment 54160.0 4270.0 0.25 63840.0 11800.0 0.9 0.8086 0.8699 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 E24 mock treatment 49960.0 73.8 0.0 51360.0 -644.0 -0.05 -0.0314 -0.6426 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F01 compound treatment 32480.0 -17400.0 -1.01 34000.0 -18000.0 -1.36 -1.6767 -0.989 3063510 Maybridge4_001167 Fc1cccc(Cl)c1CN2CCC(CC2)NS(=O)(=O)c3ccc(cc3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F02 compound treatment 48200.0 -1690.0 -0.1 40280.0 -11700.0 -0.89 -0.6966 -0.7802 1623040 Maybridge4_001168 CCN(CC)c1ccc(NC(=O)Nc2ccc(OCc3ccccc3)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F03 compound treatment 29800.0 -20100.0 -1.16 32840.0 -19200.0 -1.45 -1.8486 -0.994 1283930 Maybridge4_001169 C1C(Cc2ccccc12)Nc3nc(ns3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F04 compound treatment 49760.0 -126.0 -0.01 47560.0 -4440.0 -0.34 -0.243 -0.7223 3179796 Maybridge4_001170 CC(C)(CC(=O)O)CC(=O)Nc1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F05 compound treatment 46680.0 -3210.0 -0.19 49440.0 -2560.0 -0.19 -0.2686 -0.9998 3063512 Maybridge4_001171 FC(F)(F)c1cc(cc(c1)S(=O)(=O)NCCN2CCNC2=O)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F06 compound treatment 37080.0 -12800.0 -0.74 43720.0 -8280.0 -0.63 -0.968 -0.9965 1430388 Maybridge4_001172 Cc1ccc(NC(=O)c2ccsc2)cc1NS(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F07 compound treatment 42600.0 -7290.0 -0.42 47800.0 -4200.0 -0.32 -0.5235 -0.9903 1313330 Maybridge4_001173 Cc1oc(cc1C(=O)NCc2ccc3OCOc3c2)S(=O)(=O)N4CCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F08 compound treatment 44640.0 -5250.0 -0.3 48720.0 -3280.0 -0.25 -0.3907 -0.995 3063513 Maybridge4_001174 COC(=O)C1=C(CSC1)Nc2ccccc2NS(=O)(=O)c3ccc(cc3Cl)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F09 compound treatment 34120.0 -15800.0 -0.91 35160.0 -16800.0 -1.27 -1.5475 -0.9866 1684282 Maybridge4_001175 COC(=O)c1sccc1c2ccc(CN3CCC(CC3)c4ccccc4OC)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F10 compound treatment 28440.0 -21400.0 -1.24 36920.0 -15100.0 -1.14 -1.686 -0.9991 1364415 Maybridge4_001176 Cc1oc(cc1C(=O)NC2Cc3ccccc3C2)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F11 compound treatment 43280.0 -6610.0 -0.38 46040.0 -5960.0 -0.45 -0.5898 -0.9966 3063529 Maybridge4_001177 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2ccc(COC(=O)c3ccc4OCCc4c3)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F12 compound treatment 33160.0 -16700.0 -0.97 40400.0 -11600.0 -0.88 -1.3063 -0.9988 1341364 Maybridge4_001178 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)C4CCC4)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F13 compound treatment 46080.0 -3810.0 -0.22 49960.0 -2040.0 -0.15 -0.2653 -0.985 3063530 Maybridge4_001179 O=C(NCCN1CCN(Cc2ccccc2)CC1)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F14 compound treatment 17560.0 -32300.0 -1.87 18400.0 -33600.0 -2.54 -3.123 -0.9887 1693889 Maybridge4_001180 O=C(Nc1ccccc1)Nc2ccc(CC#N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F15 compound treatment 46960.0 -2930.0 -0.17 51080.0 -924.0 -0.07 -0.1693 -0.9233 3063531 Maybridge4_001181 Cc1nc(ccc1C(=O)NN2CCOCC2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F16 compound treatment 38720.0 -11200.0 -0.65 39560.0 -12400.0 -0.94 -1.1235 -0.9832 1169808 Maybridge4_001182 O=C(Nc1cccc2ccccc12)N3CCN(CC3)c4ncccc4C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F17 compound treatment 6960.0 -42900.0 -2.49 8800.0 -43200.0 -3.27 -4.071 -0.9909 3179797 Maybridge4_001183 Cc1onc(c1C(=O)N(C(=O)c2c(C)onc2c3ccccc3)c4ncc(C)nc4C)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F18 compound treatment 41720.0 -8170.0 -0.47 42880.0 -9120.0 -0.69 -0.8229 -0.983 1265508 Maybridge4_001184 COc1ccc(OCC(O)CNC(=O)c2sccc2Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F19 compound treatment 16960.0 -32900.0 -1.91 23040.0 -29000.0 -2.19 -2.8992 -0.9976 3063532 Maybridge4_001185 COC(=O)c1cnc(nc1C(F)(F)F)N2CCCN(CC2)C(=O)c3cc(nn3C)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F20 compound treatment 48000.0 -1890.0 -0.11 48040.0 -3960.0 -0.3 -0.2894 -0.9064 3179798 Maybridge4_001186 CCOC(=O)N1CCC(CC1)NC(=O)Nc2cc(C)oc2C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F21 compound treatment 53560.0 3670.0 0.21 50440.0 -1560.0 -0.12 0.0668 0.2743 1597233 Maybridge4_001187 COc1cccc2n(C)nc(NC(=O)CSCC(=O)O)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F22 compound treatment 39240.0 -10600.0 -0.62 41160.0 -10800.0 -0.82 -1.0166 -0.9901 1439715 Maybridge4_001188 CCc1ccc(cc1)S(=O)(=O)NCC(O)COc2ccc(OC)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F23 mock treatment 48960.0 -926.0 -0.05 52440.0 436.0 0.03 -0.0146 -0.2317 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 F24 mock treatment 49000.0 -886.0 -0.05 47440.0 -4560.0 -0.35 -0.2806 -0.8034 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G01 compound treatment 49040.0 -846.0 -0.05 45400.0 -6600.0 -0.5 -0.3881 -0.7728 1075387 Maybridge4_001189 NC(=O)NC1CCCCCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G02 compound treatment 10640.0 -39200.0 -2.27 12600.0 -39400.0 -2.98 -3.7169 -0.991 1679776 Maybridge4_001190 COC(=O)c1c(C)oc(C)c1S(=O)(=O)NC2CCCCCCCCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G03 compound treatment 48480.0 -1410.0 -0.08 50640.0 -1360.0 -0.1 -0.1306 -0.9931 3063533 Maybridge4_001191 COC(=O)c1cnc(nc1C(F)(F)F)n2ncc(C#N)c2N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G04 compound treatment 48840.0 -1050.0 -0.06 43000.0 -9000.0 -0.68 -0.5248 -0.767 1394712 Maybridge4_001192 OCCN1CCN(CC1)C2=Cc3ccccc3C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G05 compound treatment 27480.0 -22400.0 -1.3 29640.0 -22400.0 -1.69 -2.1149 -0.9914 1644505 Maybridge4_001193 CC(C)(C)NC(=O)N1CCN(CC1)c2nc(ns2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G06 compound treatment 36000.0 -13900.0 -0.8 48880.0 -3120.0 -0.24 -0.7361 -0.8778 3063534 Maybridge4_001194 OC(=O)COCC(=O)N1CCN(CC1)c2cc(nc3ccccc23)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G07 compound treatment 33720.0 -16200.0 -0.94 40000.0 -12000.0 -0.91 -1.3048 -0.9999 1201054 Maybridge4_001195 COc1ccccc1NC(=S)NC2CC3CCC2C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G08 compound treatment 14840.0 -35000.0 -2.03 16920.0 -35100.0 -2.66 -3.3136 -0.9912 1231183 Maybridge4_001196 CCOC(=O)c1cccc(c1)n2sc(=O)n(C3Cc4ccccc4C3)c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G09 compound treatment 32680.0 -17200.0 -1.0 39280.0 -12700.0 -0.96 -1.3859 -0.9999 1624776 Maybridge4_001197 Clc1ccc(s1)c2csc(n2)c3ccc4OCCc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G10 compound treatment 12720.0 -37200.0 -2.15 22320.0 -29700.0 -2.25 -3.1114 -0.9998 1282547 Maybridge4_001198 COC(=O)c1ccc(n1C)S(=O)(=O)N(C2CCCCC2)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G11 compound treatment 39960.0 -9930.0 -0.58 44560.0 -7440.0 -0.56 -0.8051 -0.9999 3063535 Maybridge4_001199 COC(=O)c1cc(oc1C)S(=O)(=O)Nc2cccc(c2)c3cnco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G12 compound treatment 1440.0 -48400.0 -2.81 1560.0 -50400.0 -3.82 -4.6847 -0.9885 3063536 Maybridge4_001200 FC(F)(F)c1ccccc1n2sc(=O)n(CC3CC3)c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G13 compound treatment 32520.0 -17400.0 -1.01 38480.0 -13500.0 -1.02 -1.4353 -1.0 3178224 Maybridge4_001201 COc1ccc(Oc2ccc(cc2NS(=O)(=O)c3cccc4nonc34)C(F)(F)F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G14 compound treatment 30640.0 -19200.0 -1.12 34760.0 -17200.0 -1.31 -1.7114 -0.9969 3178225 Maybridge4_001202 FC(F)(F)c1cc(NC(=O)c2ccc(CN3C(=O)c4ccccc4C3=O)o2)ccc1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G15 compound treatment 44240.0 -5650.0 -0.33 43280.0 -8720.0 -0.66 -0.6982 -0.9475 3063537 Maybridge4_001203 OC(=O)c1sccc1S(=O)(=O)Nc2ccccc2N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G16 compound treatment 37360.0 -12500.0 -0.73 40320.0 -11700.0 -0.88 -1.1385 -0.9952 1305367 Maybridge4_001204 CC(C)(C)OC(=O)N1CCC(CNC(=O)Nc2ccccc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G17 compound treatment 40840.0 -9050.0 -0.52 39800.0 -12200.0 -0.92 -1.0238 -0.964 1532622 Maybridge4_001205 Clc1ccc(cc1Cl)n2c(SCC(=O)N3CCOCC3)nc4ccccc4c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G18 compound treatment 42640.0 -7250.0 -0.42 45480.0 -6520.0 -0.49 -0.646 -0.9967 1304189 Maybridge4_001206 Fc1ccc(cc1)c2ccc(=O)n(CCC#N)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G19 compound treatment 40440.0 -9450.0 -0.55 44120.0 -7880.0 -0.6 -0.809 -0.9991 1675293 Maybridge4_001207 Cn1nc(NC(=O)C2CCC2C(=O)O)c3c(F)cccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G20 compound treatment 42240.0 -7650.0 -0.44 46480.0 -5520.0 -0.42 -0.6089 -0.9996 1345399 Maybridge4_001208 COC(=O)c1sccc1NC(=O)c2cc(oc2C)S(=O)(=O)N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G21 compound treatment 30480.0 -19400.0 -1.12 32840.0 -19200.0 -1.45 -1.8208 -0.9921 1463889 Maybridge4_001209 Cc1ccc(C)n1c2nn(c3cccc(F)c23)S(=O)(=O)c4ccc(C)c5ccccc45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G22 compound treatment 40800.0 -9090.0 -0.53 51760.0 -244.0 -0.02 -0.3853 -0.7314 1398688 Maybridge4_001210 Cc1cc(NS(=O)(=O)c2ccc3OCCOc3c2)no1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G23 mock treatment 46600.0 -3290.0 -0.19 50400.0 -1600.0 -0.12 -0.2205 -0.9764 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 G24 mock treatment 49720.0 -166.0 -0.01 50400.0 -1600.0 -0.12 -0.0927 -0.7608 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H01 compound treatment 51120.0 1230.0 0.07 53600.0 1600.0 0.12 0.136 0.9686 1708371 Maybridge4_001211 OC(=O)COCC(=O)NC1CCN(Cc2c(F)cccc2Cl)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H02 compound treatment 43560.0 -6330.0 -0.37 45440.0 -6560.0 -0.5 -0.6105 -0.9888 3063538 Maybridge4_001212 Clc1ccc2nc(Sc3ccccc3NS(=O)(=O)c4ccc(C#N)cc4)sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H03 compound treatment 39440.0 -10400.0 -0.61 44760.0 -7240.0 -0.55 -0.8157 -0.9988 1419067 Maybridge4_001213 Cc1c(cnn1c2ccc(F)cc2)C(=O)N(Cc3ccccc3)Cc4cccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H04 compound treatment 44520.0 -5370.0 -0.31 55640.0 3640.0 0.28 -0.0252 -0.0607 1711883 Maybridge4_001214 NS(=O)(=O)c1ccc(NC(=O)CC2(CC(=O)O)CCCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H05 compound treatment 43800.0 -6090.0 -0.35 49360.0 -2640.0 -0.2 -0.3908 -0.964 1352488 Maybridge4_001215 Clc1c(sc2ccccc12)C(=O)NCCN3CCNC3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H06 compound treatment 8240.0 -41600.0 -2.41 9760.0 -42200.0 -3.2 -3.9672 -0.9904 3178226 Maybridge4_001216 FC(F)(F)c1cc(no1)c2cc(cs2)S(=O)(=O)Nc3ccc4OCCOc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H07 compound treatment 40920.0 -8970.0 -0.52 47640.0 -4360.0 -0.33 -0.6009 -0.9761 1151414 Maybridge4_001217 COc1ccccc1OCC(O)CNCc2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H08 compound treatment 51280.0 1390.0 0.08 48720.0 -3280.0 -0.25 -0.1187 -0.454 1595899 Maybridge4_001218 COC(=O)C1=C(CSC1)Nc2ccccc2NC(=O)c3ccccc3C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H09 compound treatment 31080.0 -18800.0 -1.09 35920.0 -16100.0 -1.22 -1.6313 -0.9985 3063539 Maybridge4_001219 CC(C)n1c(SCC(=O)Nc2ccccc2Cl)nc3cc(Cl)ccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H10 compound treatment 30400.0 -19500.0 -1.13 35400.0 -16600.0 -1.26 -1.687 -0.9986 3178227 Maybridge4_001220 Cc1nc(ccc1C(=O)Nc2ccccc2c3ccccc3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H11 compound treatment 19680.0 -30200.0 -1.75 24000.0 -28000.0 -2.12 -2.7364 -0.9955 1134518 Maybridge4_001221 CN(C(=O)c1ccc(Cl)cc1)c2ccc(Cl)cc2C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H12 compound treatment 35480.0 -14400.0 -0.83 36520.0 -15500.0 -1.17 -1.4189 -0.9862 1256492 Maybridge4_001222 CCCc1ccc(cc1)S(=O)(=O)Nc2ccc(C)c(NS(=O)(=O)C)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H13 compound treatment 33120.0 -16800.0 -0.97 38000.0 -14000.0 -1.06 -1.4364 -0.9991 1621469 Maybridge4_001223 CCOC(=O)C1=C(NC(=O)NC1C)C(C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H14 compound treatment 7600.0 -42300.0 -2.45 10800.0 -41200.0 -3.12 -3.9378 -0.9929 1158832 Maybridge4_001224 CCc1ccnc(NC(=O)Nc2ccccc2C(C)(C)C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H15 compound treatment 44480.0 -5410.0 -0.31 42360.0 -9640.0 -0.73 -0.7377 -0.9286 3178228 Maybridge4_001225 O=S(=O)(NN1CCOCC1)c2cc(cs2)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H16 compound treatment 26960.0 -22900.0 -1.33 28600.0 -23400.0 -1.77 -2.1919 -0.9899 1405785 Maybridge4_001226 Clc1cncc(Cl)c1N2CCCN(CC2)C(=O)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H17 compound treatment 35040.0 -14800.0 -0.86 41760.0 -10200.0 -0.78 -1.1565 -0.9987 3178229 Maybridge4_001227 Cn1c(Cc2ccsc2)nnc1Sc3nc4ccc(Cl)cc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H18 compound treatment 39720.0 -10200.0 -0.59 39120.0 -12900.0 -0.98 -1.1061 -0.9708 1596031 Maybridge4_001228 COc1ccc(OCC(O)CNC(=O)c2ccc(cc2)N(C)C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H19 compound treatment 43320.0 -6570.0 -0.38 50960.0 -1040.0 -0.08 -0.3249 -0.8361 1496534 Maybridge4_001229 COC(=O)c1ccc(n1C)S(=O)(=O)NN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H20 compound treatment 44920.0 -4970.0 -0.29 44560.0 -7440.0 -0.56 -0.6019 -0.9513 1382593 Maybridge4_001230 CCOC(=O)N1CCC(CC1)NC(=O)Nc2ccc3OCCc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H21 compound treatment 47240.0 -2650.0 -0.15 48040.0 -3960.0 -0.3 -0.3206 -0.9514 1574673 Maybridge4_001231 COc1cccc2n(C)nc(NC(=O)c3nccnc3C(=O)O)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H22 compound treatment 34400.0 -15500.0 -0.9 38920.0 -13100.0 -0.99 -1.3347 -0.9988 1461069 Maybridge4_001232 CCOc1ccccc1NC(=O)N2CCCN(CC2)c3ncccc3C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H23 mock treatment 46440.0 -3450.0 -0.2 54800.0 2800.0 0.21 0.0085 0.0291 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 H24 mock treatment 42720.0 -7170.0 -0.42 49000.0 -3000.0 -0.23 -0.4544 -0.9598 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I01 compound treatment 44520.0 -5370.0 -0.31 57760.0 5760.0 0.44 0.0883 0.1649 1638533 Maybridge4_001233 CC(C)(C)c1ccc(cc1)c2cc(NS(=O)(=O)c3ccccc3)c(s2)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I02 compound treatment 44160.0 -5730.0 -0.33 56560.0 4560.0 0.34 0.0093 0.0194 3178230 Maybridge4_001234 COC(=O)c1c(C)oc(C)c1S(=O)(=O)NCc2ccc(OC)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I03 compound treatment 48680.0 -1210.0 -0.07 50840.0 -1160.0 -0.09 -0.1117 -0.9934 1615822 Maybridge4_001235 CCC(CO)NC(=S)Nc1ccsc1C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I04 compound treatment 12280.0 -37600.0 -2.18 18200.0 -33800.0 -2.56 -3.35 -0.9968 1181672 Maybridge4_001236 COc1ccc(cc1)n2nnnc2c3c[nH]c4ccc(Cl)cc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I05 compound treatment 40880.0 -9010.0 -0.52 49480.0 -2520.0 -0.19 -0.5041 -0.9071 3178231 Maybridge4_001237 OC(=O)/C=C\C(=O)N1CCN(CC1)c2nc(ns2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I06 compound treatment 39840.0 -10000.0 -0.58 39280.0 -12700.0 -0.96 -1.0926 -0.9709 1121093 Maybridge4_001238 COC(=O)c1ccc(n1C)S(=O)(=O)NC2CCN(Cc3ccccc3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I07 compound treatment 35080.0 -14800.0 -0.86 41480.0 -10500.0 -0.8 -1.1699 -0.9993 3178232 Maybridge4_001239 CCCN(CCC)C(=S)NC1CC2CC1C=C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I08 compound treatment 9440.0 -40400.0 -2.34 13360.0 -38600.0 -2.93 -3.7254 -0.994 1340809 Maybridge4_001240 OC1CCN(CC1)C(=O)c2cccc(CN3CCN(CC3)c4nc(ns4)c5ccccc5)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I09 compound treatment 39560.0 -10300.0 -0.6 43240.0 -8760.0 -0.66 -0.8921 -0.9987 1278544 Maybridge4_001241 CN1CCN(CC1)c2ccc(NS(=O)(=O)c3cccc4nonc34)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I10 compound treatment 40920.0 -8970.0 -0.52 38960.0 -13000.0 -0.99 -1.0655 -0.955 1350689 Maybridge4_001242 COC(=O)c1ccc(n1C)S(=O)(=O)NC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I11 compound treatment 26200.0 -23700.0 -1.37 27360.0 -24600.0 -1.87 -2.2894 -0.9886 3178233 Maybridge4_001243 Cn1c(CSc2ccnc3cc(Cl)ccc23)nnc1SCC(=O)c4ccc(Cl)s4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I12 compound treatment 16960.0 -32900.0 -1.91 22600.0 -29400.0 -2.23 -2.9227 -0.9971 3063555 Maybridge4_001244 O/C(=C\Sc1nc2CCCCc2c(c1C#N)C(F)(F)F)/c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I13 compound treatment 35080.0 -14800.0 -0.86 40680.0 -11300.0 -0.86 -1.2127 -1.0 1516805 Maybridge4_001245 COC(=O)Cc1nc(NC(=O)C2CCC2C(=O)O)sc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I14 compound treatment 29760.0 -20100.0 -1.17 37840.0 -14200.0 -1.07 -1.5826 -0.9991 1616395 Maybridge4_001246 CC(C)(C)OC(=O)N1CCC(CNC(=O)c2ccc(F)cc2F)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I15 compound treatment 4160.0 -45700.0 -2.65 4360.0 -47600.0 -3.61 -4.4234 -0.9885 1670393 Maybridge4_001247 Cc1oc(cc1c2nc(no2)c3ccc(cc3)C(C)(C)C)S(=O)(=O)N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I16 compound treatment 33840.0 -16000.0 -0.93 35040.0 -17000.0 -1.28 -1.5654 -0.9874 1316867 Maybridge4_001248 CC(C)(C)c1ccc(cc1)c2nnc(SCc3cccc(c3)C(=O)N)n2c4ccc5OCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I17 compound treatment 43960.0 -5930.0 -0.34 40120.0 -11900.0 -0.9 -0.8789 -0.9128 1620610 Maybridge4_001249 OC(CNCc1ccc2OCOc2c1)COc3ccc(F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I18 compound treatment 33880.0 -16000.0 -0.93 33920.0 -18100.0 -1.37 -1.6237 -0.982 1465779 Maybridge4_001250 CC(=O)Nc1cccc(c1)n2nnc(SCC(=O)c3ccccc3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I19 compound treatment 43520.0 -6370.0 -0.37 49760.0 -2240.0 -0.17 -0.3809 -0.938 1598604 Maybridge4_001251 Cn1nc(NC(=O)CC(C)(C)CC(=O)O)c2c(F)cccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I20 compound treatment 19560.0 -30300.0 -1.76 21880.0 -30100.0 -2.28 -2.8548 -0.9917 1238878 Maybridge4_001252 Cc1oc(cc1C(=O)Nc2ccccc2)S(=O)(=O)N3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I21 compound treatment 37400.0 -12500.0 -0.72 49800.0 -2200.0 -0.17 -0.6295 -0.8479 1457140 Maybridge4_001253 Cc1ccc(C)n1c2nn(c3cccc(F)c23)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I22 compound treatment 46480.0 -3410.0 -0.2 49320.0 -2680.0 -0.2 -0.2832 -0.9999 1519073 Maybridge4_001254 O=S(=O)(NCC1CCN(CC1)S(=O)(=O)c2ccccc2)c3cccc4nonc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I23 mock treatment 50560.0 674.0 0.04 56360.0 4360.0 0.33 0.2608 0.7853 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 I24 mock treatment 44520.0 -5370.0 -0.31 50960.0 -1040.0 -0.08 -0.2757 -0.8595 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J01 compound treatment 48400.0 -1490.0 -0.09 55200.0 3200.0 0.24 0.1102 0.4291 1542762 Maybridge4_001255 OC(=O)c1nccnc1C(=O)NC2CCN(Cc3c(F)cccc3Cl)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J02 compound treatment 31720.0 -18200.0 -1.05 39400.0 -12600.0 -0.95 -1.4188 -0.9988 1359019 Maybridge4_001256 CCCc1cnc(nc1)N2CCN(CC2)C(=S)NC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J03 compound treatment 26240.0 -23600.0 -1.37 27960.0 -24000.0 -1.82 -2.2557 -0.9902 1448044 Maybridge4_001257 CC(C)n1c(SCC(=O)c2ccccc2)nc3cc(Cl)ccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J04 compound treatment 48000.0 -1890.0 -0.11 48680.0 -3320.0 -0.25 -0.2552 -0.9303 1537193 Maybridge4_001258 CCS(=O)(=O)c1ccc(O)c(NC(=O)CCCC(=O)O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J05 compound treatment 45440.0 -4450.0 -0.26 46560.0 -5440.0 -0.41 -0.4735 -0.9744 1258625 Maybridge4_001259 Cc1oc(cc1C(=O)NCCN2CCNC2=O)S(=O)(=O)N3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J06 compound treatment 34640.0 -15200.0 -0.88 41040.0 -11000.0 -0.83 -1.2114 -0.9995 1248986 Maybridge4_001260 Cc1ccc2n(CC(=O)c3ccccc3)c(=O)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J07 compound treatment 44480.0 -5410.0 -0.31 51800.0 -204.0 -0.02 -0.2324 -0.741 1612362 Maybridge4_001261 OC(=O)COCC(=O)Nc1ccc2COC(=O)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J08 compound treatment 42480.0 -7410.0 -0.43 46120.0 -5880.0 -0.45 -0.6183 -0.9998 1623545 Maybridge4_001262 COC(=O)C1=C(CSC1)Nc2ccccc2NC(=O)COCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J09 compound treatment 35400.0 -14500.0 -0.84 41680.0 -10300.0 -0.78 -1.146 -0.9994 3063556 Maybridge4_001263 FC(F)(F)c1ccnc(n1)N2CCN(CCNC(=O)NC3CCCCC3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J10 compound treatment 36840.0 -13000.0 -0.76 31600.0 -20400.0 -1.54 -1.6266 -0.946 3178332 Maybridge4_001264 O=C(CSc1nccc(n1)c2cccs2)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J11 compound treatment 19600.0 -30300.0 -1.75 23640.0 -28400.0 -2.15 -2.7589 -0.995 3178333 Maybridge4_001265 Clc1cc(ccc1NC(=O)C2CCN(CC2)C(=O)OCc3ccccc3)N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J12 compound treatment 37720.0 -12200.0 -0.7 39880.0 -12100.0 -0.92 -1.1473 -0.9915 3063557 Maybridge4_001266 Cc1csc(NC(=O)c2ccccc2C(=O)O)c1c3nc4ccccc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J13 compound treatment 34440.0 -15400.0 -0.89 31480.0 -20500.0 -1.55 -1.7313 -0.9657 3178334 Maybridge4_001267 Fc1cc(CNC(=O)c2ccc3nonc3c2)c4OCOCc4c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J14 compound treatment 25400.0 -24500.0 -1.42 25120.0 -26900.0 -2.03 -2.4421 -0.9844 1272012 Maybridge4_001268 C1COc2cc(ccc2O1)c3cn4cccnc4n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J15 compound treatment 37480.0 -12400.0 -0.72 38920.0 -13100.0 -0.99 -1.2086 -0.9876 1207844 Maybridge4_001269 Cc1ccc(cc1)c2csc3ncnc(NCCN4CCNC4=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J16 compound treatment 43400.0 -6490.0 -0.38 43160.0 -8840.0 -0.67 -0.7391 -0.9627 3063558 Maybridge4_001270 OC(=O)COCC(=O)Nc1cccc(c1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J17 compound treatment 43120.0 -6770.0 -0.39 40880.0 -11100.0 -0.84 -0.8726 -0.9395 1592295 Maybridge4_001271 Cn1nc(c(NC(=O)c2ccc(F)cc2)c1C(C)(C)C)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J18 compound treatment 8920.0 -41000.0 -2.37 12360.0 -39600.0 -3.0 -3.8002 -0.9933 1672779 Maybridge4_001272 O=C(Nc1ccccc1)Nc2ccc(C#N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J19 compound treatment 44200.0 -5690.0 -0.33 41080.0 -10900.0 -0.83 -0.8176 -0.9186 1287020 Maybridge4_001273 Nc1nccc(n1)c2nn(ccc2=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J20 compound treatment 43040.0 -6850.0 -0.4 42960.0 -9040.0 -0.68 -0.7645 -0.9663 1290569 Maybridge4_001274 CCOC(=O)N1CCC(CC1)NC(=O)c2ccccc2C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J21 compound treatment 37560.0 -12300.0 -0.71 42640.0 -9360.0 -0.71 -1.0062 -1.0 1226002 Maybridge4_001275 Cc1nn(C)cc1NC(=O)Nc2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J22 compound treatment 46440.0 -3450.0 -0.2 44200.0 -7800.0 -0.59 -0.5589 -0.8963 3178335 Maybridge4_001276 O=C(Nc1ccccc1)N(CCC#N)Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J23 mock treatment 46920.0 -2970.0 -0.17 48320.0 -3680.0 -0.28 -0.3187 -0.973 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 J24 mock treatment 48600.0 -1290.0 -0.07 47360.0 -4640.0 -0.35 -0.3012 -0.8384 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K01 compound treatment 12560.0 -37300.0 -2.16 10360.0 -41600.0 -3.15 -3.7581 -0.9831 1539150 Maybridge4_001277 CC(C)(C)c1cc2ncnc(NC3CCN(Cc4ccccc4)CC3)c2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K02 compound treatment 29240.0 -20600.0 -1.2 30640.0 -21400.0 -1.62 -1.9893 -0.989 1563937 Maybridge4_001278 COC(=O)c1c(C)oc(C)c1S(=O)(=O)Nc2ccc(cc2)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K03 compound treatment 37920.0 -12000.0 -0.69 45640.0 -6360.0 -0.48 -0.8308 -0.9842 3063559 Maybridge4_001279 CCC1CSc2nc3ccsc3c(=O)n12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K04 compound treatment 35600.0 -14300.0 -0.83 39880.0 -12100.0 -0.92 -1.2342 -0.9987 3178336 Maybridge4_001280 FC(F)(F)c1cccc(c1)N2CCN(CC2)C3=Cc4ccccc4CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K05 compound treatment 7280.0 -42600.0 -2.47 9840.0 -42200.0 -3.19 -4.0023 -0.9919 3063560 Maybridge4_001281 FC(F)(F)c1ccnc(S)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K06 compound treatment 30520.0 -19400.0 -1.12 35400.0 -16600.0 -1.26 -1.6821 -0.9984 3178337 Maybridge4_001282 COC(=O)c1ccc(n1C)S(=O)(=O)Nc2ccc(cc2)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K07 compound treatment 23000.0 -26900.0 -1.56 20680.0 -31300.0 -2.37 -2.7781 -0.9792 1176274 Maybridge4_001283 CC1CC(CC(C)(C)C1)NC(=S)NC2CC3CC2C=C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K08 compound treatment 18800.0 -31100.0 -1.8 28600.0 -23400.0 -1.77 -2.5262 -1.0 1427567 Maybridge4_001284 Cc1ccc(C)n1c2ccc(cc2)C3(O)CCSc4ccccc43 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K09 compound treatment 13960.0 -35900.0 -2.08 13520.0 -38500.0 -2.91 -3.5316 -0.9864 1358302 Maybridge4_001285 CC(C)(C)OC(=O)N1CCC(CC1)c2nc(cs2)c3ccc(Cl)s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K10 compound treatment 36520.0 -13400.0 -0.77 34080.0 -17900.0 -1.36 -1.5069 -0.9646 1583408 Maybridge4_001286 COc1ccccc1CCNS(=O)(=O)c2ccc(C(=O)O)n2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K11 compound treatment 31280.0 -18600.0 -1.08 33920.0 -18100.0 -1.37 -1.7302 -0.993 3178338 Maybridge4_001287 OC1(CCN(CC1)C(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K12 compound treatment 23120.0 -26800.0 -1.55 22640.0 -29400.0 -2.22 -2.6682 -0.9845 3063561 Maybridge4_001288 OC1(NC(=O)c2cnn(c2C(F)(F)F)c3ccccc3)C(=O)c4ccccc4C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K13 compound treatment 22040.0 -27800.0 -1.61 26880.0 -25100.0 -1.9 -2.4855 -0.9967 3178339 Maybridge4_001289 COc1ccc(NC(=O)c2ccccc2C(F)(F)F)cc1OC3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K14 compound treatment 30720.0 -19200.0 -1.11 29520.0 -22500.0 -1.7 -1.9886 -0.9786 1513815 Maybridge4_001290 CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cccc3cccnc23)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K15 compound treatment 27520.0 -22400.0 -1.3 35680.0 -16300.0 -1.24 -1.79 -0.9997 1269818 Maybridge4_001291 Cc1cc(NS(=O)(=O)c2ccc(NCN3C(=O)c4ccccc4C3=O)cc2)no1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K16 compound treatment 15120.0 -34800.0 -2.01 18440.0 -33600.0 -2.54 -3.2208 -0.9934 3178340 Maybridge4_001292 CC(C)NC(=O)CSc1nnc(c2ccc(cc2)C(C)(C)C)n1c3ccc4OCOc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K17 compound treatment 32680.0 -17200.0 -1.0 35920.0 -16100.0 -1.22 -1.5658 -0.9951 1222771 Maybridge4_001293 NC(=O)C1CCN(CC(O)COc2ccc(F)cc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K18 compound treatment 22440.0 -27400.0 -1.59 23240.0 -28800.0 -2.18 -2.664 -0.9881 1223041 Maybridge4_001294 CC(=O)Nc1cccc(c1)n2nnc(SCc3cc(Cl)cc4COCOc34)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K19 compound treatment 33080.0 -16800.0 -0.97 32960.0 -19000.0 -1.44 -1.7078 -0.9818 1546521 Maybridge4_001295 COc1ccc2[nH]c(cc2c1)C(=O)N3CCC(Cc4ccccc4)CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K20 compound treatment 32520.0 -17400.0 -1.01 33720.0 -18300.0 -1.38 -1.6901 -0.9877 1729108 Maybridge4_001296 Cc1oc(cc1c2nc(no2)c3ccc(F)cc3)S(=O)(=O)N4CCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K21 compound treatment 34600.0 -15300.0 -0.89 36160.0 -15800.0 -1.2 -1.4743 -0.9889 3178447 Maybridge4_001297 Cc1ccc(C)n1c2nn(c3cccc(F)c23)S(=O)(=O)c4cccc(c4)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K22 compound treatment 33600.0 -16300.0 -0.94 38360.0 -13600.0 -1.03 -1.3975 -0.999 1411945 Maybridge4_001298 Cc1ccc(Oc2ncccc2NS(=O)(=O)c3ccc(s3)c4ccccn4)c5CCCc51 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K23 mock treatment 43040.0 -6850.0 -0.4 46960.0 -5040.0 -0.38 -0.5504 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 K24 mock treatment 38880.0 -11000.0 -0.64 40480.0 -11500.0 -0.87 -1.0677 -0.9881 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L01 compound treatment 49280.0 -606.0 -0.04 46560.0 -5440.0 -0.41 -0.3162 -0.7646 3178448 Maybridge4_001299 COCc1cc(O)nc(SCC(=O)c2ccccc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L02 compound treatment 32480.0 -17400.0 -1.01 39040.0 -13000.0 -0.98 -1.407 -0.9999 3063562 Maybridge4_001300 Fc1ccc(cc1)S(=O)(=O)N2CCCN(CC2)c3nccc(n3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L03 compound treatment 53280.0 3390.0 0.2 56000.0 4000.0 0.3 0.3529 0.9782 3178449 Maybridge4_001301 Nc1nc(SCC(=O)c2cc(no2)c3ccccc3)ncc1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L04 compound treatment 41920.0 -7970.0 -0.46 39480.0 -12500.0 -0.95 -0.9967 -0.9453 1497829 Maybridge4_001302 CCCNC(=O)Nc1cc(ccc1O)S(=O)(=O)CC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L05 compound treatment 41400.0 -8490.0 -0.49 40800.0 -11200.0 -0.85 -0.9473 -0.9664 1614464 Maybridge4_001303 OC(CN(CCN1CCNC1=O)CC(O)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L06 compound treatment 18240.0 -31600.0 -1.83 20360.0 -31600.0 -2.4 -2.9902 -0.9913 1416766 Maybridge4_001304 Clc1ccc2scc(CNS(=O)(=O)c3cc(cs3)S(=O)(=O)c4ccccc4)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L07 compound treatment 40800.0 -9090.0 -0.53 44920.0 -7080.0 -0.54 -0.7514 -1.0 3063563 Maybridge4_001305 O=C(Nc1ccc2COC(=O)c2c1)c3cc4ccccc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L08 compound treatment 29760.0 -20100.0 -1.17 37560.0 -14400.0 -1.09 -1.5976 -0.9995 3178450 Maybridge4_001306 Cc1cc(NC(=O)NCCNc2ncccc2C(F)(F)F)c(o1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L09 compound treatment 32440.0 -17400.0 -1.01 33920.0 -18100.0 -1.37 -1.6827 -0.9889 3178451 Maybridge4_001307 FC(F)(F)c1ccnc(n1)N2CCN(CCNC(=O)c3cccs3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L10 compound treatment 42040.0 -7850.0 -0.45 39880.0 -12100.0 -0.92 -0.9704 -0.9475 3063564 Maybridge4_001308 O=C(CSc1nccc(n1)c2cccs2)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L11 compound treatment 1640.0 -48200.0 -2.8 1360.0 -50600.0 -3.83 -4.6872 -0.988 1340769 Maybridge4_001309 Cc1c(csc1C(=O)NC2CCN(Cc3ccccc3)CC2)S(=O)(=O)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L12 compound treatment 21120.0 -28800.0 -1.67 26800.0 -25200.0 -1.91 -2.5275 -0.9977 1452839 Maybridge4_001310 Clc1cccc(Oc2ccccc2)c1CNC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L13 compound treatment 43200.0 -6690.0 -0.39 40960.0 -11000.0 -0.84 -0.865 -0.9389 1545947 Maybridge4_001311 Cc1ccc(cc1)S(=O)(=O)NC(=O)OCCn2ncc3ccccc3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L14 compound treatment 24040.0 -25800.0 -1.5 22960.0 -29000.0 -2.2 -2.6134 -0.9825 1335669 Maybridge4_001312 O=C(Nc1ccccc1)Nc2ccccc2C(=O)NCC3CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L15 compound treatment 41920.0 -7970.0 -0.46 40800.0 -11200.0 -0.85 -0.926 -0.9591 1301958 Maybridge4_001313 O=C1NCCN1CCNc2cccc(C#N)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L16 compound treatment 43600.0 -6290.0 -0.36 49400.0 -2600.0 -0.2 -0.3969 -0.9584 1237826 Maybridge4_001314 OC(=O)c1cccc(NC(=O)c2nccnc2C(=O)O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L17 compound treatment 10200.0 -39700.0 -2.3 9360.0 -42600.0 -3.23 -3.9083 -0.9862 1167798 Maybridge4_001315 CCOC(=O)C1CCN(CC1)c2ccccc2CN3CCCc4cc(C)ccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L18 compound treatment 39000.0 -10900.0 -0.63 40640.0 -11400.0 -0.86 -1.0542 -0.9884 1532681 Maybridge4_001316 O=C(NCC1CC1)c2ccccc2NS(=O)(=O)c3cccc4nonc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L19 compound treatment 40120.0 -9770.0 -0.57 42360.0 -9640.0 -0.73 -0.9163 -0.9921 3178452 Maybridge4_001317 COc1ccc(OCCNC(=O)c2nccnc2C(=O)O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L20 compound treatment 43280.0 -6610.0 -0.38 43520.0 -8480.0 -0.64 -0.7247 -0.9694 3063588 Maybridge4_001318 OC(=O)COCC(=O)Nc1ccc(cc1)n2ccc(n2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L21 compound treatment 46080.0 -3810.0 -0.22 49920.0 -2080.0 -0.16 -0.2675 -0.9865 1125657 Maybridge4_001319 NC(=O)C1CCN(CC1)C(=O)Nc2cc3ccccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L22 compound treatment 36640.0 -13200.0 -0.77 39880.0 -12100.0 -0.92 -1.1916 -0.996 3063589 Maybridge4_001320 Cc1ccc(cc1)S(=O)(=O)CCSCc2csc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L23 mock treatment 43960.0 -5930.0 -0.34 52240.0 236.0 0.02 -0.2301 -0.6694 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 L24 mock treatment 52000.0 2110.0 0.12 47320.0 -4680.0 -0.35 -0.1641 -0.4375 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M01 compound treatment 39160.0 -10700.0 -0.62 42280.0 -9720.0 -0.74 -0.9599 -0.9965 1132483 Maybridge4_001321 N(c1ccccc1)c2ncnc3cc(sc23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M02 compound treatment 48080.0 -1810.0 -0.1 52040.0 36.3 0.0 -0.0721 -0.6883 1732345 Maybridge4_001322 OC(=O)CSCC(=O)N1CCN(CC1)S(=O)(=O)c2cc(Cl)cc(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M03 compound treatment 42480.0 -7410.0 -0.43 47080.0 -4920.0 -0.37 -0.567 -0.9975 1627433 Maybridge4_001323 NCCNC(=O)Cc1ccc(O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M04 compound treatment 29280.0 -20600.0 -1.19 34400.0 -17600.0 -1.33 -1.7864 -0.9985 1237825 Maybridge4_001324 O=C(Nc1nc2ccccc2c(=O)s1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M05 compound treatment 11240.0 -38600.0 -2.24 9720.0 -42300.0 -3.2 -3.8465 -0.9847 1700739 Maybridge4_001325 OC(CSc1cccs1)CSc2ccccc2NC(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M06 compound treatment 21480.0 -28400.0 -1.65 18200.0 -33800.0 -2.56 -2.9731 -0.9772 1271443 Maybridge4_001326 COC(=O)c1ccc(n1C)S(=O)(=O)Nc2ccsc2C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M07 compound treatment 34040.0 -15800.0 -0.92 33480.0 -18500.0 -1.4 -1.6407 -0.9789 3063590 Maybridge4_001327 S=C(NC(Cc1ccccc1)c2ccccc2)NC3CC4CC3C=C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M08 compound treatment 1960.0 -47900.0 -2.78 1680.0 -50300.0 -3.81 -4.657 -0.9879 1434508 Maybridge4_001328 Fc1ccc2[nH]cc(CCCN3CCN(CC3)c4nc5cc(Cl)ccc5s4)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M09 compound treatment 41360.0 -8530.0 -0.49 47720.0 -4280.0 -0.32 -0.5786 -0.9792 1293074 Maybridge4_001329 COC(=O)c1cc(oc1C)S(=O)(=O)Nc2nn(C)c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M10 compound treatment 27280.0 -22600.0 -1.31 31480.0 -20500.0 -1.55 -2.0246 -0.9964 1681613 Maybridge4_001330 O=C(NCc1ccc2OCOc2c1)c3cc4ccccc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M11 compound treatment 13680.0 -36200.0 -2.1 13480.0 -38500.0 -2.92 -3.5452 -0.9869 1565655 Maybridge4_001331 CC(C)(C)c1ccc(cc1)S(=O)(=O)N2CCC(O)(CC2)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M12 compound treatment 43080.0 -6810.0 -0.39 39680.0 -12300.0 -0.93 -0.9385 -0.9266 1050571 Maybridge4_001332 OC(=O)CCc1cccnc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M13 compound treatment 30880.0 -19000.0 -1.1 31800.0 -20200.0 -1.53 -1.86 -0.987 1126449 Maybridge4_001333 COc1ccc(NC(=O)C2CCCCC2)cc1OC3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M14 compound treatment 33880.0 -16000.0 -0.93 35720.0 -16300.0 -1.23 -1.5273 -0.9902 1537113 Maybridge4_001334 CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2ccc3OCCOc3c2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M15 compound treatment 42680.0 -7210.0 -0.42 38960.0 -13000.0 -0.99 -0.9934 -0.9267 1458162 Maybridge4_001335 CC(C)(C)c1ccc(NC(=O)c2ccc(cc2)N3C(=O)CSCC3=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M16 compound treatment 36440.0 -13400.0 -0.78 37040.0 -15000.0 -1.13 -1.3518 -0.9833 1342126 Maybridge4_001336 NC(=O)NC(=O)Cc1nc2ccccc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M17 compound treatment 32960.0 -16900.0 -0.98 32560.0 -19400.0 -1.47 -1.7341 -0.9805 1668027 Maybridge4_001337 OC(CNC1Cc2ccccc2C1)COc3ccc(F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M18 compound treatment 37320.0 -12600.0 -0.73 42240.0 -9760.0 -0.74 -1.0374 -1.0 3063591 Maybridge4_001338 OC(=O)CSc1nc2cccnc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M19 compound treatment 42120.0 -7770.0 -0.45 42680.0 -9320.0 -0.71 -0.8172 -0.9764 1290479 Maybridge4_001339 NC(=O)C1CCN(CC(O)COc2ccc3OCOc3c2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M20 compound treatment 37320.0 -12600.0 -0.73 38240.0 -13800.0 -1.04 -1.2515 -0.9846 1132021 Maybridge4_001340 COC(=O)c1scc(C)c1NS(=O)(=O)c2ccc3OCCc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M21 compound treatment 27440.0 -22400.0 -1.3 27560.0 -24400.0 -1.85 -2.2279 -0.9851 1157417 Maybridge4_001341 COc1ccc(cc1OC)S(=O)(=O)n2nc(n3c(C)ccc3C)c4c(F)cccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M22 compound treatment 46200.0 -3690.0 -0.21 45480.0 -6520.0 -0.49 -0.5002 -0.9297 1722963 Maybridge4_001342 Cc1nc(cn1C)S(=O)(=O)N2CCC(CC2)NC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M23 mock treatment 47400.0 -2490.0 -0.14 39640.0 -12400.0 -0.94 -0.7636 -0.8064 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 M24 mock treatment 49520.0 -366.0 -0.02 45080.0 -6920.0 -0.52 -0.3856 -0.7351 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N01 compound treatment 49560.0 -326.0 -0.02 53480.0 1480.0 0.11 0.0656 0.5793 1329289 Maybridge4_001343 OC(=O)c1ccccc1C(=O)NCCN2CCNC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N02 compound treatment 30880.0 -19000.0 -1.1 34280.0 -17700.0 -1.34 -1.7273 -0.9952 3178453 Maybridge4_001344 FC(F)(F)c1ccnc(n1)N2CCCN(CC2)S(=O)(=O)c3cccc4nonc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N03 compound treatment 39840.0 -10000.0 -0.58 42120.0 -9880.0 -0.75 -0.9406 -0.9923 1118431 Maybridge4_001345 CCOC(=O)c1cc(NC(=O)CC(C)(C)CC(=O)O)ccc1N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N04 compound treatment 30160.0 -19700.0 -1.14 35960.0 -16000.0 -1.21 -1.6669 -0.9995 1615128 Maybridge4_001346 CCS(=O)(=O)c1ccc(O)c(NC(=O)Nc2ccccc2OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N05 compound treatment 34760.0 -15100.0 -0.88 40480.0 -11500.0 -0.87 -1.2365 -1.0 3178454 Maybridge4_001347 Cc1nc(cn1C)S(=O)(=O)NCCNc2ccc(nn2)c3ccc(F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N06 compound treatment 31520.0 -18400.0 -1.06 35400.0 -16600.0 -1.26 -1.6411 -0.9966 3063592 Maybridge4_001348 FC(F)(F)c1ccc(cc1)S(=O)(=O)Nc2ccc3COC(=O)c3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N07 compound treatment 33960.0 -15900.0 -0.92 36280.0 -15700.0 -1.19 -1.4941 -0.9921 1059288 Maybridge4_001349 O=C1NC(Nc2ccccc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N08 compound treatment 17920.0 -32000.0 -1.85 19440.0 -32600.0 -2.46 -3.0525 -0.9901 3063593 Maybridge4_001350 Cc1cc(NC(=O)Nc2ccccc2)c(o1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N09 compound treatment 33000.0 -16900.0 -0.98 36320.0 -15700.0 -1.19 -1.5313 -0.9954 3178455 Maybridge4_001351 COc1cccc(c1)C(=O)NCCN2CCN(CC2)c3nccc(n3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N10 compound treatment 36240.0 -13600.0 -0.79 43560.0 -8440.0 -0.64 -1.011 -0.9944 1126742 Maybridge4_001352 Cc1cc(NC(=O)CCCC(=O)O)n(C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N11 compound treatment 2360.0 -47500.0 -2.75 2440.0 -49600.0 -3.75 -4.5999 -0.9884 1374549 Maybridge4_001353 COc1ccccc1C2CCN(CC2)C(=O)c3scc(c3C)S(=O)(=O)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N12 compound treatment 16520.0 -33400.0 -1.93 17920.0 -34100.0 -2.58 -3.1913 -0.9899 1540730 Maybridge4_001354 Cc1oc(cc1C(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N13 compound treatment 35160.0 -14700.0 -0.85 34960.0 -17000.0 -1.29 -1.5156 -0.9798 1417640 Maybridge4_001355 O=C(Nc1cccc2ccccc12)OCCn3ncc4ccccc4c3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N14 compound treatment 37120.0 -12800.0 -0.74 32000.0 -20000.0 -1.51 -1.5937 -0.9457 1318344 Maybridge4_001356 COC(=O)c1sccc1S(=O)(=O)Nc2ccc3OCCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N15 compound treatment 33520.0 -16400.0 -0.95 38280.0 -13700.0 -1.04 -1.405 -0.999 3178549 Maybridge4_001357 FC(F)(F)Oc1ccc(NC(=S)NCCN2CCNC2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N16 compound treatment 10000.0 -39900.0 -2.31 10040.0 -42000.0 -3.18 -3.8801 -0.9878 1460315 Maybridge4_001358 COc1ccc(OCC(O)CNC(=O)c2cc(nn2C)C(C)(C)C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N17 compound treatment 25000.0 -24900.0 -1.44 27360.0 -24600.0 -1.87 -2.3386 -0.9919 1196797 Maybridge4_001359 CCCc1c(cnn1c2ccccc2)C(=O)NC3CCN(Cc4ccccc4)CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N18 compound treatment 23160.0 -26700.0 -1.55 21200.0 -30800.0 -2.33 -2.7437 -0.9802 3178550 Maybridge4_001360 COc1cc(OCc2ccccc2)ccc1CN3CCN(CC3)c4ccc(cn4)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N19 compound treatment 29000.0 -20900.0 -1.21 28360.0 -23600.0 -1.79 -2.1212 -0.9818 1300856 Maybridge4_001361 O=C(NC1Cc2ccccc2C1)Nc3cc4ccccc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N20 compound treatment 36760.0 -13100.0 -0.76 44000.0 -8000.0 -0.61 -0.9662 -0.9937 1617412 Maybridge4_001362 OC(=O)CC(CC(=O)N1CCN(CC1)C(=O)c2ccco2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N21 compound treatment 16320.0 -33600.0 -1.94 17560.0 -34400.0 -2.61 -3.2187 -0.9896 1534103 Maybridge4_001363 OC(COc1ccc(cc1)c2csnn2)CN3CCN(CC3)C(c4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N22 compound treatment 32840.0 -17000.0 -0.99 39640.0 -12400.0 -0.94 -1.3601 -0.9996 3063594 Maybridge4_001364 Clc1ccc(c(Cl)c1)S(=O)(=O)CCSCc2csc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N23 mock treatment 46000.0 -3890.0 -0.23 40960.0 -11000.0 -0.84 -0.7503 -0.8667 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 N24 mock treatment 43160.0 -6730.0 -0.39 46960.0 -5040.0 -0.38 -0.5455 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O01 compound treatment 15800.0 -34100.0 -1.97 18360.0 -33600.0 -2.55 -3.1972 -0.9921 1379542 Maybridge4_001365 CC(C)(C)c1cc2ncnc(N3CCCCC3)c2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O02 compound treatment 38960.0 -10900.0 -0.63 45120.0 -6880.0 -0.52 -0.8161 -0.9953 1268570 Maybridge4_001366 Cc1cc(OCC(=O)N(C2CCCCC2)c3ccccc3)c4ccccc4n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O03 compound treatment 41040.0 -8850.0 -0.51 49680.0 -2320.0 -0.18 -0.4868 -0.8983 3063595 Maybridge4_001367 FC(F)(F)c1ccn(n1)S(=O)(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O04 compound treatment 30400.0 -19500.0 -1.13 36080.0 -15900.0 -1.21 -1.6506 -0.9995 1471781 Maybridge4_001368 Cc1csc2c(=O)sc(NC(=O)c3cccs3)nc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O05 compound treatment 36880.0 -13000.0 -0.75 50320.0 -1680.0 -0.13 -0.623 -0.8151 3178551 Maybridge4_001369 COC(=O)c1cn(Cc2ccc(Cl)cc2)cc(F)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O06 compound treatment 18840.0 -31000.0 -1.8 23120.0 -28900.0 -2.19 -2.8179 -0.9953 1122209 Maybridge4_001370 COC(=O)c1ccc(n1C)S(=O)(=O)N2CCCN(Cc3ccccc3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O07 compound treatment 38560.0 -11300.0 -0.66 47080.0 -4920.0 -0.37 -0.7276 -0.9641 1177633 Maybridge4_001371 CC(C)(CCO)NC(=S)NC1CC2CC1C=C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O08 compound treatment 41200.0 -8690.0 -0.5 46240.0 -5760.0 -0.44 -0.6644 -0.9975 1162225 Maybridge4_001372 CCNC(=O)c1c(C)onc1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O09 compound treatment 38400.0 -11500.0 -0.67 41760.0 -10200.0 -0.78 -1.0189 -0.9971 3063596 Maybridge4_001373 Cc1csc2c(NCCCN3CCOCC3)ncnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O10 compound treatment 24040.0 -25800.0 -1.5 26560.0 -25400.0 -1.93 -2.4207 -0.9923 3178552 Maybridge4_001374 COc1ccc(cc1)c2cc(C(=O)Nc3ccc(F)cc3)c(o2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O11 compound treatment 43840.0 -6050.0 -0.35 44840.0 -7160.0 -0.54 -0.6311 -0.9776 3063597 Maybridge4_001375 Fc1ccc(cc1)S(=O)(=O)N2CCN=C(C=C2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O12 compound treatment 30200.0 -19700.0 -1.14 29400.0 -22600.0 -1.71 -2.0164 -0.9806 1566889 Maybridge4_001376 O=C(Nc1ccc2OCCOc2c1)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O13 compound treatment 36080.0 -13800.0 -0.8 35360.0 -16600.0 -1.26 -1.4565 -0.976 3178553 Maybridge4_001377 CC(=O)Nc1c(c(nn1C)C(F)(F)F)c2cccc(c2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O14 compound treatment 27160.0 -22700.0 -1.32 28560.0 -23400.0 -1.77 -2.1859 -0.9892 1314147 Maybridge4_001378 CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cc(Cl)sc2Cl)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O15 compound treatment 42960.0 -6930.0 -0.4 46760.0 -5240.0 -0.4 -0.5644 -1.0 1617882 Maybridge4_001379 OC(=O)CC1(CC(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4)CCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O16 compound treatment 23040.0 -26800.0 -1.56 25720.0 -26300.0 -1.99 -2.5067 -0.9926 3063620 Maybridge4_001380 Cc1nc(nc(SCC(=O)c2ccc(F)cc2)c1Cl)c3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O17 compound treatment 39720.0 -10200.0 -0.59 44400.0 -7600.0 -0.58 -0.8235 -0.9999 1499688 Maybridge4_001381 NC(=O)C1CCN(Cn2nnc3ccccc23)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O18 compound treatment 8720.0 -41200.0 -2.39 10000.0 -42000.0 -3.18 -3.9347 -0.99 1432924 Maybridge4_001382 COc1ccc(CCNC(=O)c2cc3ccccc3s2)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O19 compound treatment 43680.0 -6210.0 -0.36 39200.0 -12800.0 -0.97 -0.9396 -0.9089 1075902 Maybridge4_001383 COc1ccccc1NC(=O)Nc2ccccc2OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O20 compound treatment 50200.0 314.0 0.02 51560.0 -444.0 -0.03 -0.0109 -0.2853 3063621 Maybridge4_001384 Fc1ccc(cc1)S(=O)(=O)CCN2CCN=C(C=C2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O21 compound treatment 37080.0 -12800.0 -0.74 43080.0 -8920.0 -0.68 -1.0023 -0.9989 1600262 Maybridge4_001385 O=C(CC1(CC2CC3CC(C2)C1)C3)NCc4ccc5OCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O22 compound treatment 48280.0 -1610.0 -0.09 55520.0 3520.0 0.27 0.1224 0.4341 1226207 Maybridge4_001386 OC(=O)CCn1nc(ccc1=O)c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O23 mock treatment 54240.0 4350.0 0.25 51920.0 -83.8 -0.01 0.1739 0.6891 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 O24 mock treatment 57080.0 7190.0 0.42 53800.0 1800.0 0.14 0.3909 0.8915 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P01 compound treatment 53800.0 3910.0 0.23 53400.0 1400.0 0.11 0.2351 0.9396 1550189 Maybridge4_001387 Cc1ccc(cc1)C(=O)NCCN2CCNC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P02 compound treatment 38680.0 -11200.0 -0.65 38920.0 -13100.0 -0.99 -1.1594 -0.979 3178554 Maybridge4_001388 Cc1ccsc1CNC(=O)Nc2ccc(cc2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P03 compound treatment 800.0 -49100.0 -2.84 480.0 -51500.0 -3.9 -4.7687 -0.988 3063622 Maybridge4_001389 CCOC(=O)C(C#N)C1C(=C(N)Oc2c(C)cc(Cl)cc12)C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P04 compound treatment 25000.0 -24900.0 -1.44 25920.0 -26100.0 -1.97 -2.4156 -0.9881 1160881 Maybridge4_001390 COC(=O)c1sccc1c2ccc(CN3CCCc4cc(OC)ccc34)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P05 compound treatment 37320.0 -12600.0 -0.73 41560.0 -10400.0 -0.79 -1.0738 -0.9992 1537339 Maybridge4_001391 COC(=O)c1sccc1S(=O)(=O)NC2CCS(=O)(=O)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P06 compound treatment 37200.0 -12700.0 -0.74 46000.0 -6000.0 -0.45 -0.8411 -0.9733 3178555 Maybridge4_001392 O=C1OCc2ccc(NS(=O)(=O)c3ccccc3C#N)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P07 compound treatment 16360.0 -33500.0 -1.94 21600.0 -30400.0 -2.3 -3.0008 -0.9964 1343805 Maybridge4_001393 O=C(NC1CCN(Cc2ccccc2)CC1)Nc3cc4ccccc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P08 compound treatment 32560.0 -17300.0 -1.0 33480.0 -18500.0 -1.4 -1.7013 -0.9866 3063623 Maybridge4_001394 Cc1cc(NC(=O)NCc2ccccc2)c(o1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P09 compound treatment 30160.0 -19700.0 -1.14 34400.0 -17600.0 -1.33 -1.7504 -0.9971 3178556 Maybridge4_001395 FC(F)(F)c1ccnc(n1)N2CCN(CCNC(=O)c3ccc(Cl)cc3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P10 compound treatment 36200.0 -13700.0 -0.79 40520.0 -11500.0 -0.87 -1.1754 -0.9989 1315475 Maybridge4_001396 Cc1oc(cc1C(=O)NCc2csc3ccc(Cl)cc23)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P11 compound treatment 3400.0 -46500.0 -2.69 4080.0 -47900.0 -3.63 -4.4695 -0.9893 1707754 Maybridge4_001397 Cc1c(csc1C(=O)N2CCCc3cc(C)ccc23)S(=O)(=O)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P12 compound treatment 30240.0 -19600.0 -1.14 34720.0 -17300.0 -1.31 -1.73 -0.9976 1437749 Maybridge4_001398 CC(C)c1ccc(NC(=O)c2cc(oc2C)C(C)(C)C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P13 compound treatment 30720.0 -19200.0 -1.11 42160.0 -9840.0 -0.75 -1.3121 -0.9812 3178557 Maybridge4_001399 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2ccc(COC(=O)c3cccs3)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P14 compound treatment 37360.0 -12500.0 -0.73 48400.0 -3600.0 -0.27 -0.7061 -0.9107 1200741 Maybridge4_001400 CC(C)(CC(=O)O)CC(=O)N1CCN(CC1)c2ncccc2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P15 compound treatment 30160.0 -19700.0 -1.14 39520.0 -12500.0 -0.94 -1.4763 -0.9955 1650074 Maybridge4_001401 CCOC(=O)c1ccc(NC(=S)NCCN2CCNC2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P16 compound treatment 35480.0 -14400.0 -0.83 36400.0 -15600.0 -1.18 -1.4254 -0.9855 1225431 Maybridge4_001402 COc1ccc(OCC(O)CNC(=O)c2cccnc2Oc3ccc(Cl)cc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P17 compound treatment 38400.0 -11500.0 -0.67 40320.0 -11700.0 -0.88 -1.0959 -0.9902 1670405 Maybridge4_001403 CCCc1c(cnn1c2ccccc2)C(=O)NC3Cc4ccccc4C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P18 compound treatment 8560.0 -41300.0 -2.39 11800.0 -40200.0 -3.04 -3.8449 -0.993 1600703 Maybridge4_001404 COc1cc(OCc2ccccc2)ccc1CN3CCC(CC3)C(=O)c4ccc(F)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P19 compound treatment 12520.0 -37400.0 -2.16 14320.0 -37700.0 -2.85 -3.5478 -0.9907 1497768 Maybridge4_001405 Fc1ccc(NC(=O)Nc2cc3ccccc3s2)c(F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P20 compound treatment 2400.0 -47500.0 -2.75 3640.0 -48400.0 -3.66 -4.534 -0.9901 1490941 Maybridge4_001406 Cc1nnsc1C(=O)NCc2c(Cl)cccc2Sc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P21 compound treatment 36520.0 -13400.0 -0.77 36960.0 -15000.0 -1.14 -1.3528 -0.9823 1271550 Maybridge4_001407 OC(CNCc1ccc2OCOc2c1)COc3ccc(cc3)c4csnn4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P22 compound treatment 26360.0 -23500.0 -1.36 33040.0 -19000.0 -1.44 -1.9788 -0.9997 3063624 Maybridge4_001408 CC1(C)CCc2cc(CN3CCN(CC3)c4ncc(cc4Cl)C(F)(F)F)ccc2O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P23 mock treatment 43840.0 -6050.0 -0.35 43640.0 -8360.0 -0.63 -0.6954 -0.9611 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2052 P24 mock treatment 45640.0 -4250.0 -0.25 45000.0 -7000.0 -0.53 -0.5488 -0.9391 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A01 compound treatment 55400.0 1530.0 0.09 55160.0 8520.0 0.65 0.5186 0.7965 1291502 Maybridge4_001409 Fc1ccc(cc1)c2n[nH]cc2CN3CCN(Cc4ccccc4)CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A02 compound treatment 49520.0 -4360.0 -0.25 48160.0 1520.0 0.12 -0.0969 -0.3494 1286225 Maybridge4_001410 O=C(NC1CCN(CC1)C(=O)OCc2ccccc2)Nc3ccccc3N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A03 compound treatment 42200.0 -11700.0 -0.68 36560.0 -10100.0 -0.76 -1.0177 -0.9982 1251898 Maybridge4_001411 Cc1cc(C)c(SCC(=O)NCc2ccc3OCOc3c2)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A04 compound treatment 62440.0 8570.0 0.5 53000.0 6360.0 0.48 0.6914 0.9999 1262294 Maybridge4_001412 CCCCN1Cc2c([nH]c3cc(nn3c2=O)C(C)(C)C)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A05 compound treatment 50480.0 -3400.0 -0.2 45160.0 -1480.0 -0.11 -0.2182 -0.9642 1594634 Maybridge4_001413 OC(=O)CCCC(=O)NC1CCCc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A06 compound treatment 34440.0 -19400.0 -1.13 25960.0 -20700.0 -1.57 -1.903 -0.9869 3178643 Maybridge4_001414 COc1cc2CCN(Cc3sc4ccccc4c3C)C(C)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A07 compound treatment 48240.0 -5640.0 -0.33 37880.0 -8760.0 -0.66 -0.6996 -0.9468 1319283 Maybridge4_001415 OC(CNC(=O)Nc1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A08 compound treatment 41720.0 -12200.0 -0.7 38160.0 -8480.0 -0.64 -0.9517 -0.9989 1715585 Maybridge4_001416 Cc1cccc(NC(=O)c2ccco2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A09 compound treatment 53800.0 -75.0 0.0 44320.0 -2320.0 -0.18 -0.1271 -0.7244 1554836 Maybridge4_001417 CCCc1cnc(nc1)N2CCN(CC2)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A10 compound treatment 30320.0 -23600.0 -1.36 20920.0 -25700.0 -1.95 -2.3415 -0.9849 3178644 Maybridge4_001418 O=S(=O)(Nc1ccccc1N2CCOCC2)c3ccc(s3)c4ccccn4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A11 compound treatment 33320.0 -20600.0 -1.19 23760.0 -22900.0 -1.73 -2.0666 -0.9833 3178645 Maybridge4_001419 Cc1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A12 compound treatment 59600.0 5730.0 0.33 48280.0 1640.0 0.12 0.3225 0.9103 3063626 Maybridge4_001420 Oc1nnc(S)n1C2CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A13 compound treatment 48440.0 -5440.0 -0.31 37720.0 -8920.0 -0.68 -0.7 -0.9397 3178646 Maybridge4_001421 CN(C(=O)c1c(C)onc1c2c(Cl)cccc2Cl)c3nnc(s3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A14 compound treatment 46600.0 -7280.0 -0.42 38760.0 -7880.0 -0.6 -0.7197 -0.9856 3063627 Maybridge4_001422 N#Cc1sc2nc3ccccc3n2c1/N=C/N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A15 compound treatment 37880.0 -16000.0 -0.93 33640.0 -13000.0 -0.98 -1.351 -0.9996 3178647 Maybridge4_001423 FC(F)(F)c1ccnc(n1)N2CCC(CC2)C(=O)Oc3ccccc3N4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A16 compound treatment 44680.0 -9200.0 -0.53 39920.0 -6720.0 -0.51 -0.7362 -0.9997 1004868 Maybridge4_001424 Sc1ncnc2n(ncc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A17 compound treatment 53920.0 45.0 0.0 49640.0 3000.0 0.23 0.1625 0.7152 1225276 Maybridge4_001425 COc1ccc(NC(=O)CC2N(CCNC2=O)C(=O)c3ccc(cc3)C(C)(C)C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A18 compound treatment 1120.0 -52800.0 -3.06 1160.0 -45500.0 -3.44 -4.5954 -0.9982 1212340 Maybridge4_001426 COc1ccc(cc1)C(=O)Nc2ccc(nc2)N3CCN(CC3)C(=O)OC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A19 compound treatment 28440.0 -25400.0 -1.47 20360.0 -26300.0 -1.99 -2.4485 -0.9891 1490823 Maybridge4_001427 Fc1ccc(cc1)c2cn3cccc(OCc4ccc(Cl)c(Cl)c4)c3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A20 compound treatment 60040.0 6170.0 0.36 48080.0 1440.0 0.11 0.3298 0.8829 1164040 Maybridge4_001428 Oc1ccccc1C(=O)Nc2ccc(NC(=O)Nc3ccccc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A21 compound treatment 42280.0 -11600.0 -0.67 36920.0 -9720.0 -0.74 -0.9951 -0.999 1589639 Maybridge4_001429 O=C(Nc1ccc(OCc2ccccc2)cc1)N3CCN(CC3)c4ccccn4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A22 compound treatment 59480.0 5610.0 0.32 46040.0 -598.0 -0.05 0.1976 0.6028 1548910 Maybridge4_001430 CCOC(=O)Cc1csc(NS(=O)(=O)c2cn(C)cn2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A23 mock treatment 59200.0 5330.0 0.31 53840.0 7200.0 0.55 0.6037 0.9637 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 A24 mock treatment 65240.0 11400.0 0.66 58520.0 11900.0 0.9 1.1016 0.9882 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B01 compound treatment 58320.0 4450.0 0.26 53080.0 6440.0 0.49 0.5269 0.9555 3178648 Maybridge4_001431 Clc1ccc2c(Oc3ccc(NS(=O)(=O)c4ccc(s4)c5ccccn5)cn3)ncnc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B02 compound treatment 46280.0 -7600.0 -0.44 44400.0 -2240.0 -0.17 -0.4309 -0.9139 3178649 Maybridge4_001432 O=C(c1sc(Nc2ccc3OCCOc3c2)nc1c4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B03 compound treatment 54760.0 885.0 0.05 54120.0 7480.0 0.57 0.4368 0.768 1669153 Maybridge4_001433 CCc1ccc(cc1)C(=O)Nc2ccc(cc2)S(=O)(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B04 compound treatment 59440.0 5570.0 0.32 53640.0 7000.0 0.53 0.6028 0.9716 3178650 Maybridge4_001434 O=C(NCc1ccsc1)c2ccc3OCCCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B05 compound treatment 53400.0 -475.0 -0.03 40880.0 -5760.0 -0.44 -0.3276 -0.7503 3063628 Maybridge4_001435 CCc1c(nnc2cc(C)nn12)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B06 compound treatment 19560.0 -34300.0 -1.99 20440.0 -26200.0 -1.98 -2.808 -1.0 1347207 Maybridge4_001436 COc1ccc(Cn2cnc3n(C)c(=O)n(C)c(=O)c23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B07 compound treatment 51240.0 -2640.0 -0.15 45400.0 -1240.0 -0.09 -0.1742 -0.9725 1134750 Maybridge4_001437 CC(=O)Nc1ccc(NC(=O)Nc2ccccc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B08 compound treatment 55280.0 1410.0 0.08 46240.0 -398.0 -0.03 0.0363 0.4181 1513237 Maybridge4_001438 CSc1c2CCCCc2c(C#N)c3nc4ccccc4n13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B09 compound treatment 44720.0 -9160.0 -0.53 40840.0 -5800.0 -0.44 -0.6854 -0.9956 3178651 Maybridge4_001439 Fc1ccc(cc1)S(=O)(=O)CCSc2nnc(OC(=O)c3cccs3)n2C4CC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B10 compound treatment 49680.0 -4200.0 -0.24 44040.0 -2600.0 -0.2 -0.3109 -0.9945 3063629 Maybridge4_001440 N#Cc1c(/N=C/N2CCCCC2)nc3CCCCc3c1c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B11 compound treatment 51320.0 -2560.0 -0.15 38280.0 -8360.0 -0.63 -0.552 -0.8496 3178652 Maybridge4_001441 COC(=O)c1sccc1S(=O)(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B12 compound treatment 280.0 -53600.0 -3.11 240.0 -46400.0 -3.51 -4.6791 -0.9981 3063630 Maybridge4_001442 O=C(CN1C(=O)c2ccccc2S1(=O)=O)c3ccc4OCCCOc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B13 compound treatment 26560.0 -27300.0 -1.58 25520.0 -21100.0 -1.6 -2.2493 -1.0 1504288 Maybridge4_001443 COc1ccc(cc1)C(=O)Nc2ccc3[nH]ccc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B14 compound treatment 57560.0 3690.0 0.21 44840.0 -1800.0 -0.14 0.0548 0.2163 1589222 Maybridge4_001444 OC(=O)CCC(=O)NCC1COc2ccccc2O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B15 compound treatment 51560.0 -2320.0 -0.13 39920.0 -6720.0 -0.51 -0.4544 -0.8641 1127725 Maybridge4_001445 CCOC(=O)c1nn(c2ccccc2)c3nc(Nc4ccc(C)cc4)cc(=O)n13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B16 compound treatment 19520.0 -34400.0 -1.99 21560.0 -25100.0 -1.9 -2.7497 -0.9997 1720808 Maybridge4_001446 O=C(CSc1ccccc1)N2c3ccccc3Sc4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B17 compound treatment 37320.0 -16600.0 -0.96 31040.0 -15600.0 -1.18 -1.5131 -0.9947 1598554 Maybridge4_001447 COc1ccc(cc1)C(=O)c2c(NC(=O)C)sc3CN(CCc23)C(=O)OC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B18 compound treatment 45240.0 -8640.0 -0.5 36760.0 -9880.0 -0.75 -0.8824 -0.9809 3063652 Maybridge4_001448 C/C(=N\O)/C(C)(C)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B19 compound treatment 44320.0 -9560.0 -0.55 43280.0 -3360.0 -0.25 -0.5712 -0.9376 3063653 Maybridge4_001449 Oc1nnc(SCC(=O)c2ccc(cc2)N3CCOCC3)n1C4CC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B20 compound treatment 58680.0 4810.0 0.28 52880.0 6240.0 0.47 0.531 0.9682 3063654 Maybridge4_001450 FC(F)(F)c1cc(cc(c1)C(F)(F)F)c2ccc(COC(=O)Nc3ccccc3)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B21 compound treatment 59120.0 5250.0 0.3 49040.0 2400.0 0.18 0.3435 0.9699 3063655 Maybridge4_001451 Cc1cc2c(NC(=O)COCC(=O)O)cccc2nn1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B22 compound treatment 57320.0 3450.0 0.2 56200.0 9560.0 0.72 0.653 0.8696 3178653 Maybridge4_001452 CCOC(=O)N1CCC(CC1)NC(=O)c2snnc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B23 mock treatment 65360.0 11500.0 0.67 59080.0 12400.0 0.94 1.1365 0.9855 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 B24 mock treatment 58440.0 4570.0 0.26 55040.0 8400.0 0.64 0.6368 0.9244 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C01 compound treatment 40080.0 -13800.0 -0.8 43400.0 -3240.0 -0.25 -0.7384 -0.8833 3178654 Maybridge4_001453 COc1ccc(cc1)n2ccc(nc2=S)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C02 compound treatment 9000.0 -44900.0 -2.6 7960.0 -38700.0 -2.93 -3.9086 -0.9982 1547772 Maybridge4_001454 Cc1c(cnn1c2ccc(F)cc2)C(=O)NC3CCN(Cc4ccccc4)CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C03 compound treatment 2480.0 -51400.0 -2.98 20640.0 -26000.0 -1.97 -3.497 -0.9798 1661624 Maybridge4_001455 Cc1ccc(cc1)C(=O)Nc2ccc3ccccc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C04 compound treatment 41720.0 -12200.0 -0.7 39560.0 -7080.0 -0.54 -0.8768 -0.9909 1628233 Maybridge4_001456 CCCCN1Cc2c(C1=O)n(CC(=O)c3ccc(OC)cc3)c4cc(nn4c2=O)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C05 compound treatment 53160.0 -715.0 -0.04 43040.0 -3600.0 -0.27 -0.2218 -0.8054 1204335 Maybridge4_001457 O=C1N(CNc2ccccc2)C(=O)C3=C1CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C06 compound treatment 46000.0 -7880.0 -0.46 37760.0 -8880.0 -0.67 -0.7978 -0.9822 3178655 Maybridge4_001458 COc1ccccc1C2CCN(Cc3sc4ccccc4c3C)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C07 compound treatment 37320.0 -16600.0 -0.96 26960.0 -19700.0 -1.49 -1.7314 -0.9773 1326929 Maybridge4_001459 Cc1ccc(cc1C)C(=O)Nc2ccc(CN3CCS(=O)(=O)CC3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C08 compound treatment 46120.0 -7760.0 -0.45 41080.0 -5560.0 -0.42 -0.6152 -0.9995 1479015 Maybridge4_001460 O=C(Nc1ccccc1N2CCOCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C09 compound treatment 47760.0 -6120.0 -0.35 36800.0 -9840.0 -0.74 -0.7771 -0.9423 1487787 Maybridge4_001461 CCCc1cnc(nc1)N2CCN(CC2)S(=O)(=O)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C10 compound treatment 49400.0 -4480.0 -0.26 45120.0 -1520.0 -0.11 -0.2646 -0.9329 3063656 Maybridge4_001462 Cn1cc(c(n1)C(F)(F)F)S(=O)(=O)Nc2ccccc2N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C11 compound treatment 40720.0 -13200.0 -0.76 41400.0 -5240.0 -0.4 -0.8193 -0.9536 3178656 Maybridge4_001463 COc1ccc(cc1)n2nc(cc2c3cccs3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C12 compound treatment 50640.0 -3240.0 -0.19 38160.0 -8480.0 -0.64 -0.5863 -0.877 3063657 Maybridge4_001464 C(/N=C/1\S/C(=N/c2ccccc2)/C/3=C1/CCCC3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C13 compound treatment 54920.0 1050.0 0.06 44840.0 -1800.0 -0.14 -0.0534 -0.3586 1606533 Maybridge4_001465 OC(=O)CC(CC(=O)Nc1ccc(Oc2ccccc2)cc1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C14 compound treatment 47280.0 -6600.0 -0.38 37200.0 -9440.0 -0.71 -0.7753 -0.957 3178742 Maybridge4_001466 Clc1ccc(/C=N/n2cnc3n(ncc3c2=N)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C15 compound treatment 48560.0 -5320.0 -0.31 43560.0 -3080.0 -0.23 -0.3825 -0.9905 1551950 Maybridge4_001467 CCOC(=O)c1cn(nc1N)C(=O)CCSc2ccc(OC)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C16 compound treatment 35720.0 -18200.0 -1.05 30320.0 -16300.0 -1.24 -1.6172 -0.9968 1274385 Maybridge4_001468 CCOC(=O)C1=C(N)Oc2c(C1c3ccccc3)c(=O)oc4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C17 compound treatment 49680.0 -4200.0 -0.24 41960.0 -4680.0 -0.35 -0.4222 -0.9832 1585094 Maybridge4_001469 O=S(=O)(N(CCC#N)Cc1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C18 compound treatment 22160.0 -31700.0 -1.84 18440.0 -28200.0 -2.13 -2.8085 -0.9972 1144333 Maybridge4_001470 CC(C)(C)OC(=O)N1CCN(CC1)c2ccc(NS(=O)(=O)c3ccc(Cl)cc3)cn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C19 compound treatment 54880.0 1010.0 0.06 46040.0 -598.0 -0.05 0.0092 0.1247 1395168 Maybridge4_001471 OC(=O)c1ccccc1C(=O)NC2CCCCNC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C20 compound treatment 59040.0 5170.0 0.3 49080.0 2440.0 0.18 0.3423 0.9732 3178743 Maybridge4_001472 Oc1nnc(SCC(=O)c2ccc3OCCOc3c2)n1c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C21 compound treatment 58440.0 4570.0 0.26 51200.0 4560.0 0.35 0.4312 0.9913 1500505 Maybridge4_001473 CCOC(=O)c1cc(C)nc(N2CCC(CC2)C(=O)N)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C22 compound treatment 62640.0 8770.0 0.51 56280.0 9640.0 0.73 0.8752 0.9843 3178744 Maybridge4_001474 CCOC(=O)c1cnn(C(=O)c2snnc2C)c1N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C23 mock treatment 60080.0 6210.0 0.36 50280.0 3640.0 0.28 0.4492 0.9914 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 C24 mock treatment 57280.0 3410.0 0.2 55960.0 9320.0 0.71 0.6385 0.8714 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D01 compound treatment 60200.0 6330.0 0.37 50880.0 4240.0 0.32 0.4862 0.9978 1160532 Maybridge4_001475 Clc1ccc2c(Oc3ccc(NC(=O)Nc4ccccc4)cn3)ncnc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D02 compound treatment 42920.0 -11000.0 -0.63 38080.0 -8560.0 -0.65 -0.9068 -0.9999 3063658 Maybridge4_001476 Oc1ccc(cc1O)C(=O)CN2C(=O)c3ccccc3S2(=O)=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D03 compound treatment 42080.0 -11800.0 -0.68 41560.0 -5080.0 -0.38 -0.755 -0.9629 1237081 Maybridge4_001477 CN(C1CCCCC1)S(=O)(=O)c2ccc3ccccc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D04 compound treatment 42200.0 -11700.0 -0.68 38360.0 -8280.0 -0.63 -0.9213 -0.9993 3063659 Maybridge4_001478 OC(CN1CCN(CC1)C2c3ccccc3-c4ccccc24)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D05 compound treatment 45000.0 -8880.0 -0.51 36280.0 -10400.0 -0.78 -0.918 -0.9791 1413068 Maybridge4_001479 COC(=O)c1nn(c2ccccc2)c(=O)c3c(N)sc(C)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D06 compound treatment 28120.0 -25800.0 -1.49 24840.0 -21800.0 -1.65 -2.2218 -0.9987 3178745 Maybridge4_001480 C(On1nnc2ccccc12)c3ccccc3COn4nnc5ccccc45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D07 compound treatment 24520.0 -29400.0 -1.7 20320.0 -26300.0 -1.99 -2.6112 -0.9969 3063660 Maybridge4_001481 CCN(C(=O)c1ccc2OCCc2c1)c3cccc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D08 compound treatment 57920.0 4050.0 0.23 46920.0 283.0 0.02 0.1808 0.7684 1525376 Maybridge4_001482 CC(=O)N(C(=O)C)c1cc(C)c(C#N)c2nc3ccccc3n12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D09 compound treatment 39720.0 -14200.0 -0.82 32400.0 -14200.0 -1.08 -1.342 -0.9909 3063661 Maybridge4_001483 Cc1nnsc1c2nnc(SCC(=O)c3ccc(C)cc3)n2C4CC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D10 compound treatment 54080.0 205.0 0.01 42400.0 -4240.0 -0.32 -0.2184 -0.6805 1489082 Maybridge4_001484 Cn1c2ccccc2n3c(=O)cc(c(C#N)c13)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D11 compound treatment 51520.0 -2360.0 -0.14 41800.0 -4840.0 -0.37 -0.3554 -0.9095 1735545 Maybridge4_001485 CN(CCc1ccccn1)C(=O)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D12 compound treatment 50920.0 -2960.0 -0.17 45760.0 -878.0 -0.07 -0.168 -0.915 3178746 Maybridge4_001486 Oc1ccccc1C(=O)NC(=O)c2ccccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D13 compound treatment 47800.0 -6080.0 -0.35 42640.0 -4000.0 -0.3 -0.4628 -0.9972 3178747 Maybridge4_001487 C1CCC(CC1)/N=C/2\S/C(=N\c3ccccc3)/C/4=C2/CCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D14 compound treatment 54840.0 965.0 0.06 45440.0 -1200.0 -0.09 -0.0246 -0.2306 3063662 Maybridge4_001488 OC(=O)CCCC(=O)N1CCN(CC1)c2ncccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D15 compound treatment 26600.0 -27300.0 -1.58 18280.0 -28400.0 -2.15 -2.6352 -0.9887 1539797 Maybridge4_001489 CCOC(=O)C1=NN(c2ccccc2)C3(C1c4ccc(C)cc4)C(=O)c5ccccc5C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D16 compound treatment 59160.0 5290.0 0.31 44040.0 -2600.0 -0.2 0.0775 0.2129 1582785 Maybridge4_001490 Cc1cc(C)c2c(n1)sc3c(=O)n(CC(=O)c4ccccc4)cnc32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D17 compound treatment 52040.0 -1840.0 -0.11 44320.0 -2320.0 -0.18 -0.1992 -0.9712 3178748 Maybridge4_001491 OC(=O)c1ccc(cc1)c2cn3cccnc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D18 compound treatment 29280.0 -24600.0 -1.42 24840.0 -21800.0 -1.65 -2.1743 -0.9973 3063663 Maybridge4_001492 C/C(=N\O)/C(C)(C)Nc1ccc(Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D19 compound treatment 44360.0 -9520.0 -0.55 38240.0 -8400.0 -0.64 -0.8393 -0.9975 1236138 Maybridge4_001493 Cc1nc(Nc2ccccc2)sc1C(=O)c3cc4ccccc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D20 compound treatment 49680.0 -4200.0 -0.24 43400.0 -3240.0 -0.25 -0.3451 -1.0 3063664 Maybridge4_001494 FC(F)(F)c1ccccc1NS(=O)(=O)c2ccc3OCCc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D21 compound treatment 59040.0 5170.0 0.3 45680.0 -958.0 -0.07 0.1604 0.5208 3178749 Maybridge4_001495 O=C(NCCN1CCNC1=O)c2ccc3nccnc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D22 compound treatment 14880.0 -39000.0 -2.26 16680.0 -30000.0 -2.27 -3.201 -1.0 3178750 Maybridge4_001496 Cc1nc(cs1)c2ccc(s2)S(=O)(=O)N3CCCc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D23 mock treatment 59640.0 5770.0 0.33 50160.0 3520.0 0.27 0.4247 0.9938 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 D24 mock treatment 54920.0 1050.0 0.06 48120.0 1480.0 0.11 0.1222 0.9581 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E01 compound treatment 48240.0 -5640.0 -0.33 41880.0 -4760.0 -0.36 -0.4855 -0.9988 3063665 Maybridge4_001497 Cc1ccc(cc1)c2ccn(c3ccc(C)c(Cl)c3)c(=S)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E02 compound treatment 38680.0 -15200.0 -0.88 39760.0 -6880.0 -0.52 -0.9906 -0.9686 1172555 Maybridge4_001498 O=C(Nc1ccc(cc1)c2cn3CCSc3n2)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E03 compound treatment 55040.0 1170.0 0.07 47440.0 803.0 0.06 0.0907 0.9986 1326393 Maybridge4_001499 OC(=O)c1ccccc1C(=O)N2CCN(Cc3ccncc3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E04 compound treatment 55920.0 2050.0 0.12 45080.0 -1560.0 -0.12 4.0E-4 0.0025 1616068 Maybridge4_001500 Clc1ccccc1N2CCN(CC2)C3=Cc4ccccc4CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E05 compound treatment 37200.0 -16700.0 -0.97 26520.0 -20100.0 -1.52 -1.7599 -0.9759 1429251 Maybridge4_001501 O=C(NC1CCCc2ccccc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E06 compound treatment 37320.0 -16600.0 -0.96 30200.0 -16400.0 -1.24 -1.558 -0.9917 1274546 Maybridge4_001502 Cc1c(CN2CCc3ccccc3C2)sc4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E07 compound treatment 55160.0 1290.0 0.07 40800.0 -5840.0 -0.44 -0.2598 -0.5798 1237910 Maybridge4_001503 O=C(Nc1ccc(CN2CCS(=O)(=O)CC2)cc1)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E08 compound treatment 53000.0 -875.0 -0.05 45520.0 -1120.0 -0.08 -0.0957 -0.97 1710600 Maybridge4_001504 Cn1cnc(c1)S(=O)(=O)Nc2ccccc2N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E09 compound treatment 51720.0 -2160.0 -0.12 43000.0 -3640.0 -0.28 -0.283 -0.936 1424693 Maybridge4_001505 Cc1ccc(NC(=O)N(CCC(=O)O)Cc2ccccc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E10 compound treatment 19680.0 -34200.0 -1.98 20280.0 -26400.0 -2.0 -2.8117 -1.0 1251028 Maybridge4_001506 CC(C)(C)c1cn2cccc(OCc3ccc(Cl)c(Cl)c3)c2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E11 compound treatment 34000.0 -19900.0 -1.15 25200.0 -21400.0 -1.62 -1.9617 -0.9859 1143941 Maybridge4_001507 O=S(=O)(NC1CCCc2ccccc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E12 compound treatment 50320.0 -3560.0 -0.21 42680.0 -3960.0 -0.3 -0.3575 -0.9833 3178751 Maybridge4_001508 Nc1c(cnn1c2ccccc2)c3n[nH]c(=S)n3c4ccc(Cl)cc4Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E13 compound treatment 36880.0 -17000.0 -0.98 32200.0 -14400.0 -1.09 -1.469 -0.9986 3063666 Maybridge4_001509 FC(F)(F)c1ccn(n1)c2ccc(NC(=O)Nc3ccccc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E14 compound treatment 37080.0 -16800.0 -0.97 30600.0 -16000.0 -1.21 -1.5465 -0.994 3178752 Maybridge4_001510 CCOC(=O)COc1nc(cc(c1C#N)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E15 compound treatment 52400.0 -1480.0 -0.09 45040.0 -1600.0 -0.12 -0.1459 -0.9856 1607723 Maybridge4_001511 CCOC(=O)c1cnn(C(=O)c2c(C)nc3ccccn23)c1N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E16 compound treatment 55400.0 1530.0 0.09 44880.0 -1760.0 -0.13 -0.0316 -0.1978 1572679 Maybridge4_001512 Cc1nn(c2ccccc2)c3[nH]c(=O)c(C#N)c(c4cccs4)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E17 compound treatment 51240.0 -2640.0 -0.15 41760.0 -4880.0 -0.37 -0.369 -0.9236 1609957 Maybridge4_001513 O=S(=O)(N(CCC#N)CCc1ccccn1)c2ccc3OCCc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E18 compound treatment 43400.0 -10500.0 -0.61 33680.0 -13000.0 -0.98 -1.1227 -0.9734 1377637 Maybridge4_001514 S=C(Nc1ccc2OCCOc2c1)Nc3ccccc3N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E19 compound treatment 55240.0 1370.0 0.08 50000.0 3360.0 0.25 0.2359 0.8851 1175800 Maybridge4_001515 OC(=O)CCC(=O)NC1CCCCNC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E20 compound treatment 44160.0 -9720.0 -0.56 42000.0 -4640.0 -0.35 -0.6462 -0.9742 1593716 Maybridge4_001516 CC(c1ccccc1)n2c(O)nnc2SCc3cc(=O)oc4cc(O)ccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E21 compound treatment 49760.0 -4120.0 -0.24 41680.0 -4960.0 -0.38 -0.4339 -0.976 1417192 Maybridge4_001517 CCOC(=O)C1CCN(CC1)C(=O)c2ccc(CC)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E22 compound treatment 37640.0 -16200.0 -0.94 28480.0 -18200.0 -1.37 -1.637 -0.9829 3063667 Maybridge4_001518 Cc1nnsc1c2nnc(SCC(=O)N(C3CCCCC3)c4ccccc4)n2C5CC5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E23 mock treatment 58240.0 4370.0 0.25 49600.0 2960.0 0.22 0.3374 0.9982 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 E24 mock treatment 57320.0 3450.0 0.2 48720.0 2080.0 0.16 0.2526 0.9932 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F01 compound treatment 44120.0 -9760.0 -0.57 41960.0 -4680.0 -0.35 -0.65 -0.9746 1399434 Maybridge4_001519 Cc1ccc(cc1)C(O)COC2=NCNc3cc(Cl)ccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F02 compound treatment 51120.0 -2760.0 -0.16 44760.0 -1880.0 -0.14 -0.2134 -0.9983 3063693 Maybridge4_001520 Clc1ccc(c(Cl)c1)S(=O)(=O)CCN2C(=O)c3ccccc3S2(=O)=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F03 compound treatment 53840.0 -35.0 0.0 39960.0 -6680.0 -0.51 -0.3588 -0.7099 1228123 Maybridge4_001521 COC(=O)c1cc(oc1C)S(=O)(=O)N(C)C2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F04 compound treatment 55360.0 1490.0 0.09 45240.0 -1400.0 -0.11 -0.014 -0.1024 3063694 Maybridge4_001522 Cc1nc(sc1c2nnc(o2)c3cccc4ccccc34)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F05 compound treatment 40200.0 -13700.0 -0.79 35440.0 -11200.0 -0.85 -1.1596 -0.9994 1500694 Maybridge4_001523 CC(=O)Nc1cc(nn(c2ccccc2)c1=O)C(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F06 compound treatment 55360.0 1490.0 0.09 48680.0 2040.0 0.15 0.1702 0.9617 3063695 Maybridge4_001524 S=c1[nH]nc(c2ccncc2)n1/N=C/c3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F07 compound treatment 48760.0 -5120.0 -0.3 45640.0 -998.0 -0.08 -0.2629 -0.8598 1217417 Maybridge4_001525 CCOC(=O)c1cc2cc(OCc3ccccc3)ccc2n1C(=O)c4ccccc4C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F08 compound treatment 57520.0 3650.0 0.21 48000.0 1360.0 0.1 0.2223 0.9457 1688932 Maybridge4_001526 NNC(=O)Cn1nc(c2ccccc2)c(c(C#N)c1=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F09 compound treatment 49920.0 -3960.0 -0.23 38480.0 -8160.0 -0.62 -0.5987 -0.9089 3178837 Maybridge4_001527 CCc1cc(C(=O)c2ccc(OC)cc2)c(NC(=O)c3ccc(cc3)C(F)(F)F)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F10 compound treatment 43200.0 -10700.0 -0.62 31000.0 -15600.0 -1.18 -1.2743 -0.9542 1686628 Maybridge4_001528 NNC(=O)c1oc2nc(cc(c3ccccc3)c2c1N)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F11 compound treatment 58640.0 4770.0 0.28 44480.0 -2160.0 -0.16 0.0797 0.2486 1119276 Maybridge4_001529 CN(CCc1ccccn1)C(=O)NS(=O)(=O)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F12 compound treatment 45840.0 -8040.0 -0.47 40560.0 -6080.0 -0.46 -0.6545 -1.0 3063696 Maybridge4_001530 Fc1ccc(cc1)C(=O)CN2C(=O)c3ccccc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F13 compound treatment 50000.0 -3880.0 -0.22 44480.0 -2160.0 -0.16 -0.2742 -0.9878 1398696 Maybridge4_001531 Cn1c(SCc2n[nH]c(=S)n2CC=C)nnc1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F14 compound treatment 56120.0 2250.0 0.13 43800.0 -2840.0 -0.21 -0.0599 -0.2386 3063697 Maybridge4_001532 OC(=O)c1ccccc1C(=O)N2CCN(CC2)c3ncccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F15 compound treatment 49040.0 -4840.0 -0.28 38800.0 -7840.0 -0.59 -0.6176 -0.9413 3178838 Maybridge4_001533 Fc1ccc(cc1)C(=O)COc2nnc(SCCS(=O)(=O)c3ccc(F)cc3)n2C4CC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F16 compound treatment 34520.0 -19400.0 -1.12 29080.0 -17600.0 -1.33 -1.7327 -0.9964 3063698 Maybridge4_001534 O=C/1N(Cc2ccccc2)c3ccccc3\C1=N\c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F17 compound treatment 28120.0 -25800.0 -1.49 22040.0 -24600.0 -1.86 -2.3717 -0.994 3178839 Maybridge4_001535 CCOC(=O)C1=NN(C(=C2C(=O)c3ccccc3C2=O)C1c4cccs4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F18 compound treatment 37600.0 -16300.0 -0.94 32720.0 -13900.0 -1.05 -1.4117 -0.9985 3063699 Maybridge4_001536 COc1ccc(cc1OC)C(=O)NC(=O)c2ccccc2O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F19 compound treatment 52440.0 -1440.0 -0.08 45560.0 -1080.0 -0.08 -0.1165 -1.0 1600649 Maybridge4_001537 O=C(N1CCOCC1)c2ccc3OCCCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F20 compound treatment 7520.0 -46400.0 -2.69 5480.0 -41200.0 -3.12 -4.102 -0.9973 3063700 Maybridge4_001538 CCN(c1cccc2ccccc12)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F21 compound treatment 32560.0 -21300.0 -1.23 28000.0 -18600.0 -1.41 -1.8708 -0.9978 3178840 Maybridge4_001539 O=C(NCCc1ccccn1)c2ccc3nccnc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F22 compound treatment 53560.0 -315.0 -0.02 45960.0 -678.0 -0.05 -0.0492 -0.9033 3178841 Maybridge4_001540 CC(C)(C)OC(=O)N1CCCN(CC1)C(=O)c2cccnc2Oc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F23 mock treatment 55440.0 1570.0 0.09 49120.0 2480.0 0.19 0.197 0.9441 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 F24 mock treatment 58440.0 4570.0 0.26 52600.0 5960.0 0.45 0.5062 0.9676 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G01 compound treatment 43720.0 -10200.0 -0.59 36880.0 -9760.0 -0.74 -0.9383 -0.9937 3063701 Maybridge4_001541 COc1ccc(cc1n2ccc(nc2=S)c3ccc(C)cc3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G02 compound treatment 10480.0 -43400.0 -2.51 10560.0 -36100.0 -2.73 -3.7088 -0.9991 1377005 Maybridge4_001542 Cc1ccc(cc1C)C(=O)Nc2ccc(cc2)c3cn4CCSc4n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G03 compound treatment 45200.0 -8680.0 -0.5 33240.0 -13400.0 -1.01 -1.0725 -0.9476 1733649 Maybridge4_001543 CC(C)c1ccc(NC(=O)CSCc2csc3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G04 compound treatment 28400.0 -25500.0 -1.48 27240.0 -19400.0 -1.47 -2.0819 -1.0 1177034 Maybridge4_001544 Cc1ccc(cc1)n2nnnc2c3c[nH]c4cc(Cl)c(F)cc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G05 compound treatment 6400.0 -47500.0 -2.75 5920.0 -40700.0 -3.08 -4.1243 -0.9984 3178842 Maybridge4_001545 Clc1ccc2OCC(=Cc2c1)C(=O)NC3CCCc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G06 compound treatment 51600.0 -2280.0 -0.13 39560.0 -7080.0 -0.54 -0.472 -0.8556 1406389 Maybridge4_001546 CCCCc1ccc(NC(=O)Nc2ccc(cc2)N3CCCCC3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G07 compound treatment 37120.0 -16800.0 -0.97 34720.0 -11900.0 -0.9 -1.3243 -0.9993 1501125 Maybridge4_001547 Cc1nnsc1C(=O)Nc2ccc(CN3CCS(=O)(=O)CC3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G08 compound treatment 31920.0 -22000.0 -1.27 25000.0 -21600.0 -1.64 -2.0576 -0.9922 3063702 Maybridge4_001548 CCN(CC)S(=O)(=O)c1ccc(cc1)c2cc(sc2C(F)(F)F)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G09 compound treatment 51000.0 -2880.0 -0.17 39440.0 -7200.0 -0.54 -0.503 -0.883 1046775 Maybridge4_001549 O=C1CCN(Cc2ccccc2)C(=O)N1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G10 compound treatment 49520.0 -4360.0 -0.25 38720.0 -7920.0 -0.6 -0.6022 -0.9261 1245508 Maybridge4_001550 Clc1ccc(Cl)c(NC(=O)CC2N(CCNC2=O)C(=O)Nc3ccccc3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G11 compound treatment 41880.0 -12000.0 -0.69 39080.0 -7560.0 -0.57 -0.8959 -0.9953 3063703 Maybridge4_001551 COc1ccc(OCC2CN=C(Nc3ccc(C)cc3)S2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G12 compound treatment 42160.0 -11700.0 -0.68 34160.0 -12500.0 -0.94 -1.1478 -0.9869 3178843 Maybridge4_001552 Clc1ccc(/C=N/n2cnc3n(ncc3c2=O)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G13 compound treatment 48000.0 -5880.0 -0.34 39560.0 -7080.0 -0.54 -0.6195 -0.976 3063704 Maybridge4_001553 CC(C)N(CCC#N)C(=O)Nc1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G14 compound treatment 46080.0 -7800.0 -0.45 33360.0 -13300.0 -1.01 -1.03 -0.9348 1165894 Maybridge4_001554 Cn1c(SCC=C)nnc1c2oc3nc(cc(c4ccccc4)c3c2N)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G15 compound treatment 39040.0 -14800.0 -0.86 33080.0 -13600.0 -1.03 -1.3334 -0.9961 3063705 Maybridge4_001555 Cc1ccc(cc1)C(O)CSc2nnc(c3ccc4ccccc4c3)n2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G16 compound treatment 45960.0 -7920.0 -0.46 41640.0 -5000.0 -0.38 -0.5917 -0.9954 3178844 Maybridge4_001556 CC1CCc2c(C1)sc3ncn(CC=C)c(=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G17 compound treatment 46920.0 -6960.0 -0.4 39160.0 -7480.0 -0.57 -0.6852 -0.9861 1415511 Maybridge4_001557 CC(C)c1ccc(NC(=O)COc2ncnc3cc(Cl)ccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G18 compound treatment 47440.0 -6440.0 -0.37 35000.0 -11600.0 -0.88 -0.8865 -0.9268 3063706 Maybridge4_001558 CN(C1CCCCC1)C(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G19 compound treatment 39880.0 -14000.0 -0.81 39520.0 -7120.0 -0.54 -0.9543 -0.9803 1222950 Maybridge4_001559 COc1ccc(Cc2nnc(SCC3CC3)n2c4ccc(F)cc4)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G20 compound treatment 56120.0 2250.0 0.13 36600.0 -10000.0 -0.76 -0.4453 -0.5777 3063707 Maybridge4_001560 Oc1nnc(SCc2cc(=O)oc3cc(O)ccc23)n1Cc4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G21 compound treatment 37840.0 -16000.0 -0.93 31240.0 -15400.0 -1.17 -1.4811 -0.9937 1138850 Maybridge4_001561 CCOC(=O)C1CCN(CC1)C(=O)C2Cc3ccccc3N2C(=O)OCc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G22 compound treatment 56440.0 2570.0 0.15 48000.0 1360.0 0.1 0.178 0.9841 3063708 Maybridge4_001562 O=S(=O)(Nc1ccccc1C#N)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G23 mock treatment 50120.0 -3760.0 -0.22 39920.0 -6720.0 -0.51 -0.5134 -0.9283 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 G24 mock treatment 56760.0 2890.0 0.17 44360.0 -2280.0 -0.17 -0.0037 -0.0154 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H01 compound treatment 43200.0 -10700.0 -0.62 38720.0 -7920.0 -0.6 -0.8611 -0.9999 3178845 Maybridge4_001563 Oc1nnc(SCCS(=O)(=O)c2ccc(F)cc2)n1Cc3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H02 compound treatment 53320.0 -555.0 -0.03 47120.0 483.0 0.04 0.0031 0.0635 3063709 Maybridge4_001564 Cc1noc(C)c1c2nc(CN3C(=O)c4ccccc4S3(=O)=O)no2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H03 compound treatment 51240.0 -2640.0 -0.15 45000.0 -1640.0 -0.12 -0.1956 -0.9947 3178846 Maybridge4_001565 OC(=O)COCC(=O)Nc1ccc(Oc2cccc(c2)C(F)(F)F)nc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H04 compound treatment 46200.0 -7680.0 -0.44 46680.0 42.5 0.0 -0.3122 -0.702 1968939 Maybridge4_001566 CC(C)(CC(=O)O)CC(=O)N1CCN(CC1)C2c3ccccc3-c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H05 compound treatment 41640.0 -12200.0 -0.71 35920.0 -10700.0 -0.81 -1.0749 -0.9977 3178847 Maybridge4_001567 COC(=O)C1N(N=C(C=C1C(=O)OC)C(=O)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H06 compound treatment 37680.0 -16200.0 -0.94 33640.0 -13000.0 -0.98 -1.3592 -0.9997 1661945 Maybridge4_001568 Clc1cccc(NC(=O)N2CCCn3c(SCC=C)nnc23)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H07 compound treatment 42320.0 -11600.0 -0.67 35720.0 -10900.0 -0.83 -1.0577 -0.9945 3178848 Maybridge4_001569 Oc1nnc(SCC(=O)Nc2ccccc2)n1Cc3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H08 compound treatment 52320.0 -1560.0 -0.09 42040.0 -4600.0 -0.35 -0.3098 -0.8618 1169532 Maybridge4_001570 NNC(=O)CN1c2ccccc2Sc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H09 compound treatment 41360.0 -12500.0 -0.73 37400.0 -9240.0 -0.7 -1.0071 -0.9998 3178849 Maybridge4_001571 Clc1cc(Cl)cc(Oc2ccc(o2)C(=O)NC3Cc4ccccc4C3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H10 compound treatment 31120.0 -22800.0 -1.32 24000.0 -22600.0 -1.71 -2.1439 -0.9916 3063710 Maybridge4_001572 N#Cc1sc2nc3ccccc3n2c1/N=C/c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H11 compound treatment 13440.0 -40400.0 -2.34 13480.0 -33200.0 -2.51 -3.4313 -0.9994 1394169 Maybridge4_001573 O=C(Nc1ccc(OCc2ccccc2)cc1)N3CCN(CC3)C(=O)C4COc5ccccc5O4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H12 compound treatment 40520.0 -13400.0 -0.77 35200.0 -11400.0 -0.87 -1.1593 -0.9984 3063711 Maybridge4_001574 O=C1Nc2ccccc2C1Cc3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H13 compound treatment 24480.0 -29400.0 -1.7 23200.0 -23400.0 -1.77 -2.4587 -0.9998 1163008 Maybridge4_001575 S=C(Nc1ccccc1)C(C#N)c2nc3ccccc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H14 compound treatment 43520.0 -10400.0 -0.6 36480.0 -10200.0 -0.77 -0.9679 -0.9925 3063712 Maybridge4_001576 NS(=O)(=O)c1ccc(cc1)N(S(=O)(=O)c2ccccc2)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H15 compound treatment 27920.0 -26000.0 -1.5 22800.0 -23800.0 -1.8 -2.3392 -0.9959 3178934 Maybridge4_001577 CC(C)(C)c1ccc(cc1)c2noc(CSc3nnc(O)n3c4cccnc4)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H16 compound treatment 30680.0 -23200.0 -1.34 26560.0 -20100.0 -1.52 -2.0249 -0.9981 1688554 Maybridge4_001578 CCNc1nc(SCC(=O)OCC)nc2sc3CC(C)CCc3c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H17 compound treatment 47640.0 -6240.0 -0.36 42320.0 -4320.0 -0.33 -0.4865 -0.9988 1408340 Maybridge4_001579 O=C1c2ccccc2-c3c1cnc4c(cnn34)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H18 compound treatment 51320.0 -2560.0 -0.15 42120.0 -4520.0 -0.34 -0.3465 -0.9298 3063713 Maybridge4_001580 O=C(NCC1CC1)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H19 compound treatment 35440.0 -18400.0 -1.07 28600.0 -18000.0 -1.37 -1.7207 -0.9926 1279297 Maybridge4_001581 Cc1ccc(Oc2ncccc2NC(=O)Nc3ccccc3)c4CCCc41 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H20 compound treatment 50400.0 -3480.0 -0.2 46960.0 323.0 0.02 -0.1251 -0.6169 3178935 Maybridge4_001582 Cn1cnc(c1)S(=O)(=O)N(Cc2ccccc2)Cc3ccccc3N4CCC(CC4)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H21 compound treatment 31080.0 -22800.0 -1.32 27480.0 -19200.0 -1.45 -1.9593 -0.9989 3063714 Maybridge4_001583 CC(c1ccccc1)n2c(O)nnc2SCC(=O)c3csc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H22 compound treatment 33240.0 -20600.0 -1.2 27840.0 -18800.0 -1.42 -1.8515 -0.9963 3178936 Maybridge4_001584 C1C(=Nc2ccccc2N=C1c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H23 mock treatment 53200.0 -675.0 -0.04 46320.0 -318.0 -0.02 -0.0446 -0.9727 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 H24 mock treatment 51240.0 -2640.0 -0.15 47200.0 563.0 0.04 -0.0778 -0.4912 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I01 compound treatment 43960.0 -9920.0 -0.57 43160.0 -3480.0 -0.26 -0.5923 -0.9374 3063715 Maybridge4_001585 Fc1ccc(cc1)c2oncc2c3nnnn3c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I02 compound treatment 50440.0 -3440.0 -0.2 45160.0 -1480.0 -0.11 -0.2198 -0.9629 1145291 Maybridge4_001586 O=C(Nc1ccc(cc1)c2cn3CCSc3n2)c4ccc5nonc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I03 compound treatment 55880.0 2010.0 0.12 46960.0 323.0 0.02 0.0994 0.8374 1583736 Maybridge4_001587 Cc1ccc(cc1)S(=O)(=O)NC(=O)NC2CCCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I04 compound treatment 53480.0 -395.0 -0.02 42480.0 -4160.0 -0.31 -0.2387 -0.7565 1281751 Maybridge4_001588 CN(CC(=O)O)c1ncc(c2nnnn2c3ccccc3)c(n1)c4ccccc4Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I05 compound treatment 46640.0 -7240.0 -0.42 43120.0 -3520.0 -0.27 -0.4847 -0.976 3178937 Maybridge4_001589 Cc1nc(ccc1C(=O)Oc2ccccc2N3CCCCC3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I06 compound treatment 54760.0 885.0 0.05 38920.0 -7720.0 -0.58 -0.3768 -0.6426 1529830 Maybridge4_001590 Clc1cccc(NC(=O)Nc2ccc(cc2)N3CCCCC3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I07 compound treatment 45560.0 -8320.0 -0.48 39760.0 -6880.0 -0.52 -0.7088 -0.9993 1741796 Maybridge4_001591 Cc1cc(no1)C(=O)Nc2ccc(CN3CCS(=O)(=O)CC3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I08 compound treatment 30560.0 -23300.0 -1.35 27320.0 -19300.0 -1.46 -1.9891 -0.9992 1155868 Maybridge4_001592 CC(C)N(Cc1ccccc1)S(=O)(=O)c2ccc3ccccc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I09 compound treatment 39480.0 -14400.0 -0.83 38800.0 -7840.0 -0.59 -1.0092 -0.9861 1382929 Maybridge4_001593 COc1ccc(cc1)C(=O)N2CCc3cc(OC)c(OC)cc3C2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I10 compound treatment 35880.0 -18000.0 -1.04 29120.0 -17500.0 -1.33 -1.6748 -0.9929 3178938 Maybridge4_001594 CC(C)(C)c1cc(NC(=O)Nc2ccccc2)no1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I11 compound treatment 48280.0 -5600.0 -0.32 36520.0 -10100.0 -0.77 -0.7707 -0.9268 3063716 Maybridge4_001595 Cc1nc(ccc1C(=O)NCC(O)c2ccccc2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I12 compound treatment 39600.0 -14300.0 -0.83 32960.0 -13700.0 -1.04 -1.3169 -0.9938 3178939 Maybridge4_001596 Cn1c(CSc2nnc(c3ccccc3)n2CC=C)nnc1SCc4ccc(F)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I13 compound treatment 43440.0 -10400.0 -0.6 38120.0 -8520.0 -0.64 -0.8834 -0.9995 3063717 Maybridge4_001597 CC(C)N1CCC(=O)N(C1=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I14 compound treatment 44280.0 -9600.0 -0.56 36640.0 -10000.0 -0.76 -0.9282 -0.9885 1303953 Maybridge4_001598 O=c1[nH]cnc2n(c3ccccc3)c(=S)sc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I15 compound treatment 23240.0 -30600.0 -1.77 22600.0 -24000.0 -1.82 -2.5416 -0.9999 1733519 Maybridge4_001599 Cc1nc2ccccn2c1c3ccnc(SCC(=O)N(C4CCCCC4)c5ccccc5)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I16 compound treatment 46040.0 -7840.0 -0.45 35840.0 -10800.0 -0.82 -0.8989 -0.9615 1465542 Maybridge4_001600 Cc1ccc(cc1)C(=O)CN(Cc2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I17 compound treatment 46200.0 -7680.0 -0.44 40920.0 -5720.0 -0.43 -0.6205 -0.9999 3063736 Maybridge4_001601 OC(=O)CC(CC(=O)Oc1ccccc1N2CCOCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I18 compound treatment 42440.0 -11400.0 -0.66 38760.0 -7880.0 -0.6 -0.8901 -0.9986 3063737 Maybridge4_001602 CC(C)N(Cc1ccccc1)C(=O)Nc2ccc(cc2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I19 compound treatment 50760.0 -3120.0 -0.18 42200.0 -4440.0 -0.34 -0.3651 -0.9576 1622159 Maybridge4_001603 COc1ccc(Cc2nnc(SCC(=O)NC(C)C)n2c3ccc(F)cc3)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I20 compound treatment 41160.0 -12700.0 -0.74 34000.0 -12600.0 -0.96 -1.1973 -0.9917 3063738 Maybridge4_001604 Cc1cc(C)c(c(C)c1)n2c(O)nnc2SCCS(=O)(=O)c3ccc(F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I21 compound treatment 41520.0 -12400.0 -0.72 37200.0 -9440.0 -0.71 -1.0113 -1.0 1522253 Maybridge4_001605 CCOC(=O)C1CCN(CC1)C(=O)c2sc(nc2C)c3ccc4OCCc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I22 compound treatment 50400.0 -3480.0 -0.2 39880.0 -6760.0 -0.51 -0.5041 -0.917 3063739 Maybridge4_001606 O=S(=O)(Nc1ccccc1N2CCCCC2)c3cccc4nonc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I23 mock treatment 59640.0 5770.0 0.33 47440.0 803.0 0.06 0.2791 0.8222 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 I24 mock treatment 49200.0 -4680.0 -0.27 45080.0 -1560.0 -0.12 -0.2749 -0.9306 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J01 compound treatment 1600.0 -52300.0 -3.03 1720.0 -44900.0 -3.4 -4.5458 -0.9983 1381618 Maybridge4_001607 CC(C)c1ccc(NC(=O)CSc2nnc(O)n2C(C)c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J02 compound treatment 36120.0 -17800.0 -1.03 34440.0 -12200.0 -0.92 -1.3802 -0.9985 3063740 Maybridge4_001608 Cc1onc(c1CN2C(=O)c3ccccc3S2(=O)=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J03 compound treatment 10240.0 -43600.0 -2.53 12320.0 -34300.0 -2.6 -3.6245 -0.9999 1310898 Maybridge4_001609 Clc1cccc(NC(=O)Nc2ccccc2N3CCCCC3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J04 compound treatment 45280.0 -8600.0 -0.5 38160.0 -8480.0 -0.64 -0.8059 -0.9921 1473794 Maybridge4_001610 Fc1cn(Cc2c(Cl)cccc2Cl)c(=O)[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J05 compound treatment 45120.0 -8760.0 -0.51 39920.0 -6720.0 -0.51 -0.7182 -1.0 1148553 Maybridge4_001611 CCOC(=O)c1nn(c2ccccc2)c(=O)c3c(N)c(C#N)c(cc13)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J06 compound treatment 46840.0 -7040.0 -0.41 42840.0 -3800.0 -0.29 -0.4915 -0.9854 2101411 Maybridge4_001612 O=C(Oc1c(C#N)sc2n(c3ccccc3)c(=S)n(c4ccccc4)c(=O)c12)c5cccs5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J07 compound treatment 35640.0 -18200.0 -1.06 30160.0 -16500.0 -1.25 -1.629 -0.9966 1624521 Maybridge4_001613 CC(c1ccccc1)n2c(OC(=O)N(C)C)nnc2SCC(=O)c3ccc4OCCOc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J08 compound treatment 33840.0 -20000.0 -1.16 32720.0 -13900.0 -1.05 -1.5657 -0.9988 3063741 Maybridge4_001614 CCOC(=O)c1cnn(c1NC(=O)Nc2cccc(Cl)c2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J09 compound treatment 55320.0 1450.0 0.08 42040.0 -4600.0 -0.35 -0.1869 -0.5221 3063742 Maybridge4_001615 Cc1cc(C)cc(OC(=O)c2ccc(Oc3cc(Cl)cc(Cl)c3)o2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J10 compound treatment 44160.0 -9720.0 -0.56 40760.0 -5880.0 -0.44 -0.7126 -0.9932 1606613 Maybridge4_001616 COc1cc(OC)c2nc(C)c3CN(Cc3c2c1)C(=O)Nc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J11 compound treatment 36880.0 -17000.0 -0.98 30760.0 -15900.0 -1.2 -1.5461 -0.9951 3178940 Maybridge4_001617 CN(C(=O)c1nn(nc1C)c2ccccc2)c3nnc(s3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J12 compound treatment 31240.0 -22600.0 -1.31 28080.0 -18600.0 -1.4 -1.9206 -0.9994 3063743 Maybridge4_001618 Cc1sc(nc1c2ccccc2)c3ccc(cc3)c4csnn4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J13 compound treatment 48280.0 -5600.0 -0.32 33880.0 -12800.0 -0.97 -0.912 -0.8954 3178941 Maybridge4_001619 S=c1[nH]nc(CCCCc2n[nH]c(=S)[nH]2)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J14 compound treatment 41600.0 -12300.0 -0.71 31640.0 -15000.0 -1.14 -1.3056 -0.9746 3063744 Maybridge4_001620 O=C(Nc1ccccc1N2CCOCC2)C3=NNC(=O)CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J15 compound treatment 42240.0 -11600.0 -0.67 36480.0 -10200.0 -0.77 -1.0203 -0.9979 3178942 Maybridge4_001621 Cc1c(sc2ccc(Cl)cc12)C(=O)CSc3nnc(O)n3C4CC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J16 compound treatment 4400.0 -49500.0 -2.87 4760.0 -41900.0 -3.17 -4.2683 -0.9987 1671368 Maybridge4_001622 O=C(CSc1nnc(o1)c2ccncc2)N3c4ccccc4Sc5ccccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J17 compound treatment 50320.0 -3560.0 -0.21 42200.0 -4440.0 -0.34 -0.3832 -0.9724 3178943 Maybridge4_001623 CC(C)(C)c1cc(N/C=C/C(=O)c2ccc(Cl)cc2)no1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J18 compound treatment 41160.0 -12700.0 -0.74 41200.0 -5440.0 -0.41 -0.8119 -0.9622 3178944 Maybridge4_001624 O=C(C1=NOC2(C1c3ccccc3)C(=O)c4ccccc4C2=O)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J19 compound treatment 41640.0 -12200.0 -0.71 40320.0 -6320.0 -0.48 -0.8394 -0.9816 1576744 Maybridge4_001625 Cc1ccc(Oc2ncccc2NC(=O)CC(CC(=O)O)c3ccccc3)c4CCCc41 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J20 compound treatment 45640.0 -8240.0 -0.48 38880.0 -7760.0 -0.59 -0.7526 -0.9947 1506454 Maybridge4_001626 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J21 compound treatment 41320.0 -12600.0 -0.73 30120.0 -16500.0 -1.25 -1.3984 -0.9668 3178945 Maybridge4_001627 Cc1cc(C)c(c(C)c1)n2c(O)nnc2SCC(=O)c3ccc(C#N)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J22 compound treatment 54560.0 685.0 0.04 45680.0 -958.0 -0.07 -0.0232 -0.2806 3063745 Maybridge4_001628 OC(=O)CSCC(=O)Nc1n[nH]c(SCc2ccc(Cl)cc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J23 mock treatment 51920.0 -1960.0 -0.11 43400.0 -3240.0 -0.25 -0.2534 -0.9385 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 J24 mock treatment 52720.0 -1160.0 -0.07 43720.0 -2920.0 -0.22 -0.2035 -0.8818 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K01 compound treatment 40520.0 -13400.0 -0.77 36600.0 -10000.0 -0.76 -1.0844 -1.0 3178946 Maybridge4_001629 Cc1ccccc1c2oncc2c3nnnn3c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K02 compound treatment 42880.0 -11000.0 -0.64 31520.0 -15100.0 -1.14 -1.2596 -0.9618 1125361 Maybridge4_001630 COC(=O)c1sccc1S(=O)(=O)Nc2ccc(cc2)c3cn4CCSc4n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K03 compound treatment 14080.0 -39800.0 -2.31 17480.0 -29200.0 -2.21 -3.191 -0.9998 1429606 Maybridge4_001631 CC(C)(C)c1ccc(NC(=O)NC2CCCc3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K04 compound treatment 7200.0 -46700.0 -2.7 9040.0 -37600.0 -2.85 -3.9246 -0.9997 1237562 Maybridge4_001632 CCOC(=O)C1CCCN(C1)C(=O)S(=O)(=O)c2ccc(s2)c3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K05 compound treatment 39040.0 -14800.0 -0.86 30120.0 -16500.0 -1.25 -1.4918 -0.9833 3063746 Maybridge4_001633 Cc1ccc(cc1)S(=O)(=O)NC(=O)Oc2ccccc2N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K06 compound treatment 28080.0 -25800.0 -1.49 24480.0 -22200.0 -1.68 -2.2427 -0.9983 1225155 Maybridge4_001634 O=S(=O)(Nc1ccc(cc1)N2CCCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K07 compound treatment 43160.0 -10700.0 -0.62 36600.0 -10000.0 -0.76 -0.9762 -0.995 1255708 Maybridge4_001635 Nc1ccccc1C(=O)NCCN2CCNC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K08 compound treatment 9040.0 -44800.0 -2.6 7360.0 -39300.0 -2.97 -3.9391 -0.9977 1132174 Maybridge4_001636 CC(C)N(Cc1ccccc1)S(=O)(=O)c2ccc3OCCc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K09 compound treatment 10000.0 -43900.0 -2.54 9960.0 -36700.0 -2.78 -3.7606 -0.999 1685251 Maybridge4_001637 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3nn(nc3C)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K10 compound treatment 31920.0 -22000.0 -1.27 27440.0 -19200.0 -1.45 -1.927 -0.9978 1481631 Maybridge4_001638 COc1ccc(cc1)C(=O)Nc2ccc(Oc3ncnc4cc(Cl)ccc34)nc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K11 compound treatment 38640.0 -15200.0 -0.88 29040.0 -17600.0 -1.33 -1.566 -0.98 1418693 Maybridge4_001639 OC(CNS(=O)(=O)c1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K12 compound treatment 27880.0 -26000.0 -1.51 24640.0 -22000.0 -1.67 -2.2424 -0.9987 3179042 Maybridge4_001640 Clc1ccc(cc1)C(=O)CSc2nnc(CSc3nnc(c4ccccc4)n3CC=C)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K13 compound treatment 33280.0 -20600.0 -1.19 31760.0 -14900.0 -1.13 -1.64 -0.9996 1429598 Maybridge4_001641 C(N1CCN(CC1)c2ccccn2)c3c[nH]c(n3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K14 compound treatment 12040.0 -41800.0 -2.42 13320.0 -33300.0 -2.52 -3.4972 -0.9998 1175807 Maybridge4_001642 C1Cc2nc3ncnn3c(N4CCN(CC4)c5ccccc5)c2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K15 compound treatment 36480.0 -17400.0 -1.01 30720.0 -15900.0 -1.2 -1.5646 -0.9961 1227234 Maybridge4_001643 CCOC(=O)c1cc(=O)c2ccc(OCC(=O)Nc3ccccc3)cc2o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K16 compound treatment 37080.0 -16800.0 -0.97 32400.0 -14200.0 -1.08 -1.4501 -0.9987 3179043 Maybridge4_001644 Cc1onc(NC(=O)CSCC(=O)O)c1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K17 compound treatment 34520.0 -19400.0 -1.12 35120.0 -11500.0 -0.87 -1.4094 -0.9923 1228665 Maybridge4_001645 O=C(Oc1ccccc1N2CCOCC2)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K18 compound treatment 36600.0 -17300.0 -1.0 26960.0 -19700.0 -1.49 -1.7609 -0.9813 3179044 Maybridge4_001646 CN(C1CCCCC1)C(=O)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K19 compound treatment 30480.0 -23400.0 -1.36 28280.0 -18400.0 -1.39 -1.941 -0.9999 3179045 Maybridge4_001647 COc1ccc(Cc2nnc(SCC(=O)C(C)(C)C)n2c3ccc(F)cc3)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K20 compound treatment 38360.0 -15500.0 -0.9 33800.0 -12800.0 -0.97 -1.3227 -0.9992 3063747 Maybridge4_001648 COc1cccc(NC(=O)NCCN2CCN=C2C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K21 compound treatment 38280.0 -15600.0 -0.9 32040.0 -14600.0 -1.1 -1.4202 -0.995 1463967 Maybridge4_001649 Cc1ccc(cc1)C(=O)NC2CCCCNC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K22 compound treatment 18480.0 -35400.0 -2.05 16520.0 -30100.0 -2.28 -3.0621 -0.9986 1183986 Maybridge4_001650 O=C(Nc1cccs1)Nc2nnc(s2)C3CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K23 mock treatment 46000.0 -7880.0 -0.46 32960.0 -13700.0 -1.04 -1.0547 -0.9322 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 K24 mock treatment 39840.0 -14000.0 -0.81 37880.0 -8760.0 -0.66 -1.0437 -0.9949 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L01 compound treatment 21480.0 -32400.0 -1.88 18080.0 -28600.0 -2.16 -2.8557 -0.9975 3179046 Maybridge4_001651 CC(C)c1ccc(NC(=O)CSc2nnc(O)n2C3CC3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L02 compound treatment 37480.0 -16400.0 -0.95 34960.0 -11700.0 -0.88 -1.2967 -0.9994 3063748 Maybridge4_001652 CC(C)(CC(=O)Nc1ccc(F)cc1)Sc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L03 compound treatment 23680.0 -30200.0 -1.75 25240.0 -21400.0 -1.62 -2.3823 -0.9993 1296513 Maybridge4_001653 Cc1ccccc1NC(=O)Nc2ccccc2N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L04 compound treatment 48000.0 -5880.0 -0.34 43920.0 -2720.0 -0.21 -0.3861 -0.9709 3179047 Maybridge4_001654 O=c1[nH]cc(N2CCN(Cc3ccccc3)CC2)c(=O)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L05 compound treatment 1440.0 -52400.0 -3.04 2200.0 -44400.0 -3.36 -4.5266 -0.9987 1703134 Maybridge4_001655 CC(C)(C)c1ccc(Oc2ccc(NC(=O)c3ccccc3)cn2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L06 compound treatment 41920.0 -12000.0 -0.69 39200.0 -7440.0 -0.56 -0.8879 -0.9947 3179048 Maybridge4_001656 Cc1nc2n(CC=C)c(=S)sc2c(=O)n1/N=C/c3ccc(Cl)cc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L07 compound treatment 43520.0 -10400.0 -0.6 32680.0 -14000.0 -1.06 -1.1713 -0.9641 3063749 Maybridge4_001657 CN(C)C(=O)Oc1nnc(SCC(=O)c2ccc3OCCOc3c2)n1C4Cc5ccccc5C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L08 compound treatment 40200.0 -13700.0 -0.79 27280.0 -19400.0 -1.47 -1.5963 -0.9583 1284108 Maybridge4_001658 C1CCc2c(C1)sc3ncnc(Oc4ccccc4)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L09 compound treatment 52760.0 -1120.0 -0.06 42480.0 -4160.0 -0.31 -0.2682 -0.8349 1451783 Maybridge4_001659 Cc1ccc2cc(OC(=O)c3ccc(Oc4cc(Cl)cc(Cl)c4)o3)ccc2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L10 compound treatment 44440.0 -9440.0 -0.55 31080.0 -15600.0 -1.18 -1.2192 -0.9391 3063750 Maybridge4_001660 C=CCNC(=S)Nc1sc2CCCCc2c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L11 compound treatment 35720.0 -18200.0 -1.05 30080.0 -16600.0 -1.25 -1.63 -0.9962 1501773 Maybridge4_001661 CC(C)N(Cc1ccccc1)C(=O)Nc2c(C)onc2c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L12 compound treatment 1520.0 -52400.0 -3.03 1480.0 -45200.0 -3.42 -4.5619 -0.9982 3063751 Maybridge4_001662 Clc1ccc(cc1)C2CCC(CC2)C(=O)NCc3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L13 compound treatment 44400.0 -9480.0 -0.55 39120.0 -7520.0 -0.57 -0.7905 -0.9998 3179049 Maybridge4_001663 Cc1nc2n(CC=C)c(=S)sc2c(=O)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L14 compound treatment 48280.0 -5600.0 -0.32 38720.0 -7920.0 -0.6 -0.653 -0.9584 3063752 Maybridge4_001664 COC(=O)c1cccc(NC(=O)C2=NNC(=O)CC2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L15 compound treatment 41800.0 -12100.0 -0.7 37600.0 -9040.0 -0.68 -0.9784 -0.9999 1342676 Maybridge4_001665 Cc1noc(C)c1c2nc(CSc3nnc(O)n3C4CC4)no2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L16 compound treatment 47480.0 -6400.0 -0.37 39680.0 -6960.0 -0.53 -0.6344 -0.9852 3179050 Maybridge4_001666 FC(F)(F)c1ccnc(SCn2c(=S)sc3ccccc23)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L17 compound treatment 38080.0 -15800.0 -0.92 31480.0 -15200.0 -1.15 -1.4584 -0.9937 3063753 Maybridge4_001667 Cc1ccnc(SCn2c(=S)sc3ccccc23)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L18 compound treatment 46320.0 -7560.0 -0.44 40080.0 -6560.0 -0.5 -0.6605 -0.998 3179051 Maybridge4_001668 CCOC(=O)C1=NN(C(=C2C(=O)c3ccccc3C2=O)S1)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L19 compound treatment 27640.0 -26200.0 -1.52 23360.0 -23300.0 -1.76 -2.3207 -0.9973 3063754 Maybridge4_001669 Cc1ccc(Oc2ncccc2NC(=O)c3ccc4OCCCOc4c3)c5CCCc51 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L20 compound treatment 33720.0 -20200.0 -1.17 32680.0 -14000.0 -1.06 -1.5728 -0.9988 3179052 Maybridge4_001670 CCOC(=O)N1CCC(CC1)NS(=O)(=O)c2ccc(C)c(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L21 compound treatment 29880.0 -24000.0 -1.39 28400.0 -18200.0 -1.38 -1.9592 -1.0 3179053 Maybridge4_001671 Cc1cc(C)c(c(C)c1)n2c(O)nnc2SCC(=O)Nc3ccccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L22 compound treatment 37440.0 -16400.0 -0.95 33960.0 -12700.0 -0.96 -1.3519 -1.0 3063755 Maybridge4_001672 Fc1ccc(cc1)S(=O)(=O)Nc2n[nH]c(SCc3ccc(Cl)cc3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L23 mock treatment 50320.0 -3560.0 -0.21 47720.0 1080.0 0.08 -0.0877 -0.3956 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 L24 mock treatment 51880.0 -2000.0 -0.12 41040.0 -5600.0 -0.42 -0.3813 -0.8683 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M01 compound treatment 56600.0 2730.0 0.16 49960.0 3320.0 0.25 0.2895 0.9748 1161393 Maybridge4_001673 Cc1c(cnc2cc3OCOc3cc12)c4nnnn4c5ccc(F)cc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M02 compound treatment 46920.0 -6960.0 -0.4 37840.0 -8800.0 -0.67 -0.7558 -0.971 3063756 Maybridge4_001674 Cc1cc(C)c2cc([nH]c2c1)C(=O)N3CCN(CC3)c4ncccc4C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M03 compound treatment 34520.0 -19400.0 -1.12 32080.0 -14600.0 -1.1 -1.5721 -1.0 1702105 Maybridge4_001675 Fc1ccccc1NC(=O)NC2CCCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M04 compound treatment 49400.0 -4480.0 -0.26 40920.0 -5720.0 -0.43 -0.4894 -0.97 1481828 Maybridge4_001676 OC(=O)c1ccc2nc3ccsc3c(=O)n2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M05 compound treatment 31040.0 -22800.0 -1.32 32280.0 -14400.0 -1.09 -1.704 -0.9952 3063779 Maybridge4_001677 FC(F)(F)c1ccc(nc1)N2CCN(Cc3c[nH]nc3c4ccccc4)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M06 compound treatment 27760.0 -26100.0 -1.51 24520.0 -22100.0 -1.67 -2.2537 -0.9987 3063780 Maybridge4_001678 O=S(=O)(N1CCC2(CC1)OCCO2)c3ccc(s3)c4ccccn4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M07 compound treatment 40600.0 -13300.0 -0.77 38560.0 -8080.0 -0.61 -0.9762 -0.9935 3063781 Maybridge4_001679 Cc1c(cnn1c2ccc(F)cc2)C(=O)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M08 compound treatment 17720.0 -36200.0 -2.09 17960.0 -28700.0 -2.17 -3.0161 -0.9998 1213448 Maybridge4_001680 O=C(Nc1csc2ccccc12)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M09 compound treatment 29280.0 -24600.0 -1.42 26880.0 -19800.0 -1.5 -2.0651 -0.9997 1543617 Maybridge4_001681 COc1cc2CCN(C(C)c2cc1OC)S(=O)(=O)c3ccc(s3)c4ccccn4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M10 compound treatment 44400.0 -9480.0 -0.55 32120.0 -14500.0 -1.1 -1.1652 -0.9486 1698439 Maybridge4_001682 Fc1ccc(cc1)C(=O)COc2ncnc3cc(Cl)ccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M11 compound treatment 9760.0 -44100.0 -2.56 11200.0 -35400.0 -2.68 -3.7041 -0.9997 1129209 Maybridge4_001683 CC(C)(C)c1ccc(NC(=O)Nc2ccc3OCCOc3c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M12 compound treatment 22200.0 -31700.0 -1.84 15360.0 -31300.0 -2.37 -2.9718 -0.9921 1441238 Maybridge4_001684 CC(=O)N(C(=O)C)n1c(C)nc2c(sc3nnc(c4ccccc4)c(c5ccccc5)c32)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M13 compound treatment 45600.0 -8280.0 -0.48 32480.0 -14200.0 -1.07 -1.0968 -0.9342 1158309 Maybridge4_001685 O=C(Nc1ccccc1)Oc2ccccc2N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M14 compound treatment 39760.0 -14100.0 -0.82 32920.0 -13700.0 -1.04 -1.3125 -0.993 1618806 Maybridge4_001686 C(N(Cc1ccccc1)c2c3CCCc3nc4ncnn24)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M15 compound treatment 14360.0 -39500.0 -2.29 14400.0 -32200.0 -2.44 -3.3443 -0.9995 1328356 Maybridge4_001687 Clc1ccc(cc1)C(=O)Nc2ccc3ccccc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M16 compound treatment 42560.0 -11300.0 -0.66 29080.0 -17600.0 -1.33 -1.4033 -0.947 1356245 Maybridge4_001688 Cc1cc(C)c2cc([nH]c2c1)C(=O)N3CCC(Cc4ccccc4)CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M17 compound treatment 28960.0 -24900.0 -1.44 23320.0 -23300.0 -1.77 -2.2688 -0.995 3063782 Maybridge4_001689 Clc1ccc(Sc2ncccc2C(=O)Oc3ccccc3N4CCOCC4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M18 compound treatment 40000.0 -13900.0 -0.8 26960.0 -19700.0 -1.49 -1.6217 -0.9581 1407054 Maybridge4_001690 CN(C1CCCCC1)S(=O)(=O)c2ccc(s2)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M19 compound treatment 19040.0 -34800.0 -2.02 13360.0 -33300.0 -2.52 -3.2083 -0.994 1657796 Maybridge4_001691 Cc1ccc(cc1)S(=O)(=O)Nc2ccccc2Oc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M20 compound treatment 48040.0 -5840.0 -0.34 34720.0 -11900.0 -0.9 -0.8769 -0.9103 3179139 Maybridge4_001692 CC1=NCCN1CCNC(=O)Nc2ccc(cc2)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M21 compound treatment 46200.0 -7680.0 -0.44 38680.0 -7960.0 -0.6 -0.7403 -0.9889 1606643 Maybridge4_001693 O=C1N(CCCN2CCOCC2)C(Nc3ccccc13)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M22 compound treatment 50040.0 -3840.0 -0.22 45120.0 -1520.0 -0.11 -0.2383 -0.9529 1220768 Maybridge4_001694 OC(=O)COCC(=O)Nc1nnc(s1)C2CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M23 mock treatment 44280.0 -9600.0 -0.56 40360.0 -6280.0 -0.48 -0.7291 -0.9969 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 M24 mock treatment 47920.0 -5960.0 -0.35 41800.0 -4840.0 -0.37 -0.5029 -0.9996 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N01 compound treatment 55920.0 2050.0 0.12 48080.0 1440.0 0.11 0.161 0.9992 1585891 Maybridge4_001695 CCc1cccc(C)c1NC(=O)N(Cc2ccccc2)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N02 compound treatment 42520.0 -11400.0 -0.66 40520.0 -6120.0 -0.46 -0.7926 -0.9852 3063783 Maybridge4_001696 CC1CC(=O)Nc2ccccc2N1S(=O)(=O)c3ccc(s3)c4cc(on4)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N03 compound treatment 6640.0 -47200.0 -2.74 6120.0 -40500.0 -3.07 -4.1038 -0.9984 1262463 Maybridge4_001697 O=C(Nc1cccs1)Nc2ccccc2N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N04 compound treatment 29720.0 -24200.0 -1.4 26360.0 -20300.0 -1.53 -2.0749 -0.9989 3179140 Maybridge4_001698 Fc1cn(CC2CC(=NO2)c3ccccc3)c(=O)n(CC4CC(=NO4)c5ccccc5)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N05 compound treatment 3400.0 -50500.0 -2.92 2680.0 -44000.0 -3.33 -4.4206 -0.9979 1190724 Maybridge4_001699 CC(C)(C)c1ccc(Oc2ccc(NC(=O)Nc3cccs3)cn2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N06 compound treatment 43080.0 -10800.0 -0.63 37520.0 -9120.0 -0.69 -0.9303 -0.9988 3179141 Maybridge4_001700 COc1cc(/C=N/n2cnc3n(C)c(=S)sc3c2=O)ccc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N07 compound treatment 39800.0 -14100.0 -0.82 33040.0 -13600.0 -1.03 -1.3044 -0.9934 3063784 Maybridge4_001701 CN(C)C(=O)Oc1nnc(SCCS(=O)(=O)c2ccc(F)cc2)n1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N08 compound treatment 45680.0 -8200.0 -0.47 34400.0 -12200.0 -0.93 -0.9907 -0.9518 3179142 Maybridge4_001702 CCOC(=O)c1c(SC)n(c2ccccc2)c(=S)n(c3ccccc3)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N09 compound treatment 18000.0 -35900.0 -2.08 15560.0 -31100.0 -2.35 -3.1331 -0.9981 1226040 Maybridge4_001703 CC(=O)N1CCN(CC1)c2ccc(OC(=O)c3ccc(Oc4cc(Cl)cc(Cl)c4)o3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N10 compound treatment 42040.0 -11800.0 -0.69 34000.0 -12600.0 -0.96 -1.1613 -0.9867 3063785 Maybridge4_001704 CN(C)/C=N\c1cc(C)c(C#N)c2nc3ccccc3n12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N11 compound treatment 46760.0 -7120.0 -0.41 40520.0 -6120.0 -0.46 -0.6189 -0.9983 1109792 Maybridge4_001705 OC(CN1CCOCC1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N12 compound treatment 13720.0 -40200.0 -2.33 18240.0 -28400.0 -2.15 -3.165 -0.9992 3179143 Maybridge4_001706 O=C(Cn1cc(nc1SCc2ccccc2)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N13 compound treatment 720.0 -53200.0 -3.08 720.0 -45900.0 -3.48 -4.6353 -0.9982 1537386 Maybridge4_001707 C=CCn1c(Sc2ncnc3n(ncc23)c4ccccc4)nnc1c5ccncc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N14 compound treatment 41480.0 -12400.0 -0.72 37200.0 -9440.0 -0.71 -1.0129 -1.0 3063786 Maybridge4_001708 Fc1cc(F)cc(NC(=O)C2=NNC(=O)CC2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N15 compound treatment 40280.0 -13600.0 -0.79 34800.0 -11800.0 -0.9 -1.1906 -0.9979 1514475 Maybridge4_001709 CN(CCc1ccccn1)C(=O)c2c(C)onc2c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N16 compound treatment 36360.0 -17500.0 -1.01 31240.0 -15400.0 -1.17 -1.5417 -0.9976 1207655 Maybridge4_001710 CCOc1ncc(c2nnnn2c3ccc(C)cc3)c(n1)c4cccc(Cl)c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N17 compound treatment 35320.0 -18600.0 -1.08 28040.0 -18600.0 -1.41 -1.7556 -0.9911 3179144 Maybridge4_001711 COc1ccc(cc1)C(=O)CSc2nnc(O)n2Cc3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N18 compound treatment 42520.0 -11400.0 -0.66 32560.0 -14100.0 -1.07 -1.2187 -0.9731 3063787 Maybridge4_001712 CC1CN(CC(C)O1)c2ccc3nnc(c4ccc(cc4)C(F)(F)F)n3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N19 compound treatment 46160.0 -7720.0 -0.45 30840.0 -15800.0 -1.2 -1.1616 -0.9099 3179145 Maybridge4_001713 FC(F)(F)c1ccc(cc1)C(=O)n2ccc(n2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N20 compound treatment 35360.0 -18500.0 -1.07 28840.0 -17800.0 -1.35 -1.7111 -0.9936 3179146 Maybridge4_001714 CCCc1c(cnn1c2ccccc2)C(=O)NC3CCN(CC3)C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N21 compound treatment 14280.0 -39600.0 -2.29 13800.0 -32800.0 -2.49 -3.3797 -0.9992 3063788 Maybridge4_001715 Cc1cc(C)c(c(C)c1)n2c(O)nnc2SCc3nc4ccccc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N22 compound treatment 43640.0 -10200.0 -0.59 38160.0 -8480.0 -0.64 -0.8731 -0.9992 3179147 Maybridge4_001716 O=C(Nc1ccccc1)N2CCN(CC2)c3ncccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N23 mock treatment 46920.0 -6960.0 -0.4 40400.0 -6240.0 -0.47 -0.6188 -0.9969 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 N24 mock treatment 49800.0 -4080.0 -0.24 43240.0 -3400.0 -0.26 -0.3488 -0.9991 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O01 compound treatment 59680.0 5810.0 0.34 50560.0 3920.0 0.3 0.4478 0.9981 3063789 Maybridge4_001717 NC(=O)C1CCN(CC(O)(c2ccccc2)c3ccccc3)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O02 compound treatment 58960.0 5090.0 0.29 49280.0 2640.0 0.2 0.3498 0.9822 1354647 Maybridge4_001718 O=C1N(Cc2ccccc2)Cc3c1[nH]c4cc(nn4c3=O)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O03 compound treatment 48720.0 -5160.0 -0.3 45840.0 -798.0 -0.06 -0.2539 -0.8332 1618786 Maybridge4_001719 O=C(NC1CCCc2ccccc12)Nc3ccc(OCc4ccccc4)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O04 compound treatment 49240.0 -4640.0 -0.27 41720.0 -4920.0 -0.37 -0.4531 -0.9872 1669773 Maybridge4_001720 NC(=O)c1ccc2nc3ccsc3c(=O)n2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O05 compound treatment 43280.0 -10600.0 -0.61 39520.0 -7120.0 -0.54 -0.815 -0.9979 1411321 Maybridge4_001721 COc1ccc(cc1)c2n[nH]cc2CN3CCC(CC3)c4ccccc4OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O06 compound treatment 50200.0 -3680.0 -0.21 42440.0 -4200.0 -0.32 -0.3752 -0.981 1472712 Maybridge4_001722 Cc1cc(=O)oc2cc(NC(=O)CC(CC(=O)O)c3ccccc3)ccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O07 compound treatment 48640.0 -5240.0 -0.3 38400.0 -8240.0 -0.62 -0.6554 -0.9452 1310764 Maybridge4_001723 Fc1ccc(cc1)N2CCN(CC2)C(=O)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O08 compound treatment 48360.0 -5520.0 -0.32 38680.0 -7960.0 -0.6 -0.6519 -0.956 1239250 Maybridge4_001724 O=C(Nc1csc2ccccc12)N3CCN(CC3)C(c4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O09 compound treatment 40720.0 -13200.0 -0.76 31240.0 -15400.0 -1.17 -1.3631 -0.9788 1699746 Maybridge4_001725 COc1cc2CCN(C(C)c2cc1OC)C(=O)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O10 compound treatment 40040.0 -13800.0 -0.8 33480.0 -13200.0 -1.0 -1.271 -0.9942 1354931 Maybridge4_001726 Cc1cc(no1)c2nc(CCn3c(=O)oc4ccc(C)cc34)no2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O11 compound treatment 40640.0 -13200.0 -0.77 35880.0 -10800.0 -0.81 -1.118 -0.9995 1136980 Maybridge4_001727 O=C(Nc1cccs1)Nc2ccc3OCCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O12 compound treatment 37480.0 -16400.0 -0.95 30440.0 -16200.0 -1.23 -1.5386 -0.992 3179148 Maybridge4_001728 Clc1ccc(CS/C(=N\c2ccccc2)/C(C#N)c3nc4ccccc4[nH]3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O13 compound treatment 36720.0 -17200.0 -0.99 29120.0 -17500.0 -1.33 -1.6404 -0.9899 1462458 Maybridge4_001729 Clc1ccsc1C(=O)Oc2ccccc2N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O14 compound treatment 360.0 -53500.0 -3.1 480.0 -46200.0 -3.49 -4.6629 -0.9982 3179149 Maybridge4_001730 Cn1c(Sc2c3CCCc3nc4ncnn24)nnc1c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O15 compound treatment 48520.0 -5360.0 -0.31 44880.0 -1760.0 -0.13 -0.3135 -0.9285 1250957 Maybridge4_001731 Cn1nccc1NC(=O)COCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O16 compound treatment 22080.0 -31800.0 -1.84 22680.0 -24000.0 -1.81 -2.5849 -1.0 1424513 Maybridge4_001732 COc1cc2CCN(C(C)c2cc1OC)C(=O)c3cc4c(C)cc(C)cc4[nH]3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O17 compound treatment 37480.0 -16400.0 -0.95 35400.0 -11200.0 -0.85 -1.2731 -0.9985 3063791 Maybridge4_001733 Cc1c(CN2CCN(CC2)c3ccccn3)sc4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O18 compound treatment 45560.0 -8320.0 -0.48 43560.0 -3080.0 -0.23 -0.5054 -0.9444 1224470 Maybridge4_001734 CN(CCc1ccccn1)C(=O)c2cccnc2Oc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O19 compound treatment 48440.0 -5440.0 -0.31 41160.0 -5480.0 -0.41 -0.5158 -0.9908 1228387 Maybridge4_001735 O=S(=O)(Nc1ccccc1Oc2ccccc2)c3ccc(s3)c4ccon4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O20 compound treatment 50880.0 -3000.0 -0.17 46480.0 -158.0 -0.01 -0.1311 -0.7539 3179150 Maybridge4_001736 CC1=NCCN1CCNC(=O)Nc2cc(C)cc(C)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O21 compound treatment 51760.0 -2120.0 -0.12 45000.0 -1640.0 -0.12 -0.1743 -1.0 1638495 Maybridge4_001737 O=C1NCCN1CCN2C(Nc3ccccc3C2=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O22 compound treatment 50600.0 -3280.0 -0.19 44160.0 -2480.0 -0.19 -0.2668 -1.0 3063793 Maybridge4_001738 Cc1nn(nc1c2nnc(o2)c3cccc4ccccc34)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O23 mock treatment 52920.0 -955.0 -0.06 41720.0 -4920.0 -0.37 -0.3023 -0.8034 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 O24 mock treatment 56920.0 3050.0 0.18 48560.0 1920.0 0.15 0.2276 0.9954 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P01 compound treatment 62600.0 8730.0 0.51 45840.0 -798.0 -0.06 0.3148 0.6183 1685839 Maybridge4_001739 CN(C1CCCCC1)C(=O)NS(=O)(=O)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P02 compound treatment 39560.0 -14300.0 -0.83 34240.0 -12400.0 -0.94 -1.25 -0.9981 3063794 Maybridge4_001740 CC(C)c1ccc(NC(=O)C2=NNC(=O)CC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P03 compound treatment 48880.0 -5000.0 -0.29 35920.0 -10700.0 -0.81 -0.7783 -0.9036 1248453 Maybridge4_001741 Oc1cc2c(coc2c3ccccc13)C(=O)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P04 compound treatment 42560.0 -11300.0 -0.66 34840.0 -11800.0 -0.89 -1.095 -0.9884 1427084 Maybridge4_001742 S=C(Nc1ccccc1)N2CCCCC2c3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P05 compound treatment 43640.0 -10200.0 -0.59 36680.0 -9960.0 -0.75 -0.9523 -0.993 1556607 Maybridge4_001743 CC(C)(C)c1ccc(Oc2ccc(NC(=O)CC(C)(C)CC(=O)O)cn2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P06 compound treatment 31240.0 -22600.0 -1.31 34440.0 -12200.0 -0.92 -1.5802 -0.9852 1313218 Maybridge4_001744 N#Cc1c2CCCc2c(N3CCCCC3)n4c5ccccc5nc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P07 compound treatment 33000.0 -20900.0 -1.21 27800.0 -18800.0 -1.43 -1.8635 -0.9966 3063820 Maybridge4_001745 O=C(CSc1nnc(OC(=O)c2cccs2)n1C3CC3)c4ccc5OCCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P08 compound treatment 46120.0 -7760.0 -0.45 35880.0 -10800.0 -0.81 -0.8935 -0.9607 3063821 Maybridge4_001746 Cc1nn(cc1C2C=C(N=C3SCC(=O)N23)c4ccc(Cl)cc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P09 compound treatment 45640.0 -8240.0 -0.48 36880.0 -9760.0 -0.74 -0.8596 -0.9776 3063822 Maybridge4_001747 Cc1nc(cn1C)S(=O)(=O)N2CCN(CC2)C3c4ccccc4-c5ccccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P10 compound treatment 31200.0 -22700.0 -1.31 27600.0 -19000.0 -1.44 -1.9479 -0.9989 3063823 Maybridge4_001748 O=C1N(Cc2ccc3nonc3c2)S(=O)(=O)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P11 compound treatment 30200.0 -23700.0 -1.37 29960.0 -16700.0 -1.26 -1.8626 -0.9991 1323976 Maybridge4_001749 Fc1ccc(cc1)C(=O)Nc2ccc3[nH]ccc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P12 compound treatment 31480.0 -22400.0 -1.3 32160.0 -14500.0 -1.1 -1.6924 -0.9965 3179235 Maybridge4_001750 Cc1ccccc1C(=O)Nc2n[nH]c(SCc3ccc(Cl)cc3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P13 compound treatment 34760.0 -19100.0 -1.11 29720.0 -16900.0 -1.28 -1.6886 -0.9974 1141633 Maybridge4_001751 Cc1cc(NC(=O)Nc2ccccc2)n(n1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P14 compound treatment 40720.0 -13200.0 -0.76 42560.0 -4080.0 -0.31 -0.7572 -0.9208 3179236 Maybridge4_001752 Cc1c(/C=N/N2C(=O)CNC2=S)c(=O)n3c4ccccc4[nH]c3c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P15 compound treatment 29520.0 -24400.0 -1.41 25360.0 -21300.0 -1.61 -2.1366 -0.9978 3063825 Maybridge4_001753 O=C(NCCc1cccs1)N2CCN(CC2)C3c4ccccc4-c5ccccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P16 compound treatment 41360.0 -12500.0 -0.73 35000.0 -11600.0 -0.88 -1.1356 -0.9953 3179237 Maybridge4_001754 O=C(Nc1ccc2OCCOc2c1)C3Cc4ccccc4N3C(=O)OCc5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P17 compound treatment 32800.0 -21100.0 -1.22 29760.0 -16900.0 -1.28 -1.7668 -0.9997 3179238 Maybridge4_001755 Cc1noc(C)c1CSc2nnc(O)n2Cc3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P18 compound treatment 41160.0 -12700.0 -0.74 40400.0 -6240.0 -0.47 -0.8548 -0.9769 3063826 Maybridge4_001756 NNC(=O)C1N(N=C(C=C1C(=O)NN)C(=O)c2cccs2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P19 compound treatment 23400.0 -30500.0 -1.77 26160.0 -20500.0 -1.55 -2.3445 -0.9979 3179239 Maybridge4_001757 Cc1cc(C(=O)n2ccc(n2)c3cccs3)c(C)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P20 compound treatment 44120.0 -9760.0 -0.57 41880.0 -4760.0 -0.36 -0.6543 -0.9763 1543173 Maybridge4_001758 CCOC(=O)N1CCC(CC1)NC(=O)c2cc(C)on2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P21 compound treatment 46200.0 -7680.0 -0.44 44040.0 -2600.0 -0.2 -0.4535 -0.9327 3179240 Maybridge4_001759 COc1ccc(NC(=O)COCC(=O)O)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P22 compound treatment 37280.0 -16600.0 -0.96 36400.0 -10200.0 -0.77 -1.2278 -0.9943 3179241 Maybridge4_001760 Cc1onc(c1C(=O)NCC2COc3ccccc3O2)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P23 mock treatment 45640.0 -8240.0 -0.48 44640.0 -2000.0 -0.15 -0.4443 -0.8877 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2053 P24 mock treatment 57160.0 3290.0 0.19 43600.0 -3040.0 -0.23 -0.028 -0.0938 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A01 compound treatment 54040.0 11700.0 0.68 60000.0 14400.0 1.09 1.2516 0.9733 3063827 Maybridge4_001761 Cc1noc(C)c1S(=O)(=O)NCC2COc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A02 compound treatment 34200.0 -8160.0 -0.47 50120.0 4570.0 0.35 -0.09 -0.1536 3179242 Maybridge4_001762 COc1ccc(cc1)C2C3CCc4ccccc4C3=NN2C(=O)c5cccs5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A03 compound treatment 46880.0 4520.0 0.26 46800.0 1250.0 0.09 0.2518 0.9052 3063828 Maybridge4_001763 COc1ccc(cc1)c2nnsc2N3C(=O)c4ccccc4C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A04 compound treatment 24200.0 -18200.0 -1.05 37640.0 -7910.0 -0.6 -1.1676 -0.9643 3179243 Maybridge4_001764 CCn1c(Cn2nnc3ccccc23)nnc1SCC(=O)c4ccc(Br)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A05 compound treatment 22120.0 -20200.0 -1.17 24720.0 -20800.0 -1.58 -1.9444 -0.9894 3179244 Maybridge4_001765 C1Cc2cc(ccc2O1)C3Nc4ccccc4-c5cccn35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A06 compound treatment 22240.0 -20100.0 -1.17 28320.0 -17200.0 -1.3 -1.7468 -0.9984 3063829 Maybridge4_001766 S=C(Nc1ccccc1)N2c3ccccc3Sc4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A07 compound treatment 20200.0 -22200.0 -1.28 24440.0 -21100.0 -1.6 -2.038 -0.9941 3179245 Maybridge4_001767 O=S(=O)(NCc1ccco1)c2ccc(Oc3c(C#N)cccc3C#N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A08 compound treatment 37920.0 -4440.0 -0.26 38680.0 -6870.0 -0.52 -0.5499 -0.9474 3063830 Maybridge4_001768 Nc1nc(Sc2nnc(c3ccncc3)n2c4ccccc4)ncc1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A09 compound treatment 40200.0 -2160.0 -0.13 41160.0 -4390.0 -0.33 -0.3237 -0.9111 3179246 Maybridge4_001769 Clc1ccc(COC(=O)c2ccc3ccccc3n2)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A10 compound treatment 42000.0 -364.0 -0.02 44720.0 -833.0 -0.06 -0.0595 -0.8949 3063831 Maybridge4_001770 O=C(CSc1nnc(o1)c2ccncc2)NC(=O)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A11 compound treatment 46480.0 4120.0 0.24 48200.0 2650.0 0.2 0.3103 0.9963 1526124 Maybridge4_001771 S=c1[nH]nc(c2ccncc2)n1Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A12 compound treatment 43120.0 756.0 0.04 42840.0 -2710.0 -0.21 -0.1142 -0.544 3179247 Maybridge4_001772 S=c1[nH]c(=S)c2cnc(nc2[nH]1)N3CCc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A13 compound treatment 45120.0 2760.0 0.16 49160.0 3610.0 0.27 0.306 0.9674 3063832 Maybridge4_001773 Cc1cc(C)c2c(n1)sc3c(=O)n(/N=C/c4ccccc4)cnc32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A14 compound treatment 44560.0 2200.0 0.13 45680.0 128.0 0.01 0.0968 0.7586 3179248 Maybridge4_001774 Fc1ccc(Cn2nc3sc4ccccc4n3c(=O)c2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A15 compound treatment 30600.0 -11800.0 -0.68 31800.0 -13800.0 -1.04 -1.218 -0.9789 3063833 Maybridge4_001775 Clc1ccccc1Cn2nnc3c(=S)[nH]cnc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A16 compound treatment 44440.0 2080.0 0.12 46280.0 728.0 0.06 0.124 0.9373 3179249 Maybridge4_001776 CCOC(=O)c1c(C)c(C)sc1NC(=S)Nc2cc(C)nn2c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A17 compound treatment 31800.0 -10600.0 -0.61 37360.0 -8190.0 -0.62 -0.8713 -1.0 3063834 Maybridge4_001777 CCOC(=O)c1nnn2c1nc(N(CC)CC)c3ccccc32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A18 compound treatment 42760.0 396.0 0.02 41040.0 -4510.0 -0.34 -0.2253 -0.6581 3179250 Maybridge4_001778 Cc1cc(C)c2c(n1)sc3c(=O)n(NC(=O)Nc4ccccc4)c(C)nc32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A19 compound treatment 45760.0 3400.0 0.2 49400.0 3850.0 0.29 0.3451 0.9818 3063835 Maybridge4_001779 CCOC(=O)c1nn(c2ccccc2)c3nc(=O)c(C#N)c(c4ccccc4)n13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A20 compound treatment 49320.0 6960.0 0.4 45520.0 -32.5 0.0 0.2832 0.7028 3179251 Maybridge4_001780 O=C(Cn1c(=O)n(c2ccccc2)c(=O)c3cc(sc13)c4ccccc4)c5cccs5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A21 compound treatment 40360.0 -2000.0 -0.12 47160.0 1610.0 0.12 0.0039 0.0235 3179252 Maybridge4_001781 COc1ccc(cc1)n2ncc(NC(=O)NCc3ccccn3)c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A22 compound treatment 18360.0 -24000.0 -1.39 21400.0 -24200.0 -1.83 -2.2761 -0.9909 3063836 Maybridge4_001782 COc1ccc(/C=C/2\N=C(N(/N=C/c3cccnc3)C2=O)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A23 mock treatment 47440.0 5080.0 0.29 49160.0 3610.0 0.27 0.4011 0.9993 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 A24 mock treatment 62680.0 20300.0 1.18 51480.0 5930.0 0.45 1.1496 0.9126 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B01 compound treatment 55240.0 12900.0 0.75 55880.0 10300.0 0.78 1.0803 0.9997 3179253 Maybridge4_001783 OC(=O)CSc1nnc([nH]1)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B02 compound treatment 53120.0 10800.0 0.62 59560.0 14000.0 1.06 1.1904 0.9679 3063837 Maybridge4_001784 O=c1oc2=C(c3ccccc3)S(=O)(=O)C(=c2o1)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B03 compound treatment 46680.0 4320.0 0.25 45400.0 -153.0 -0.01 0.1687 0.6737 3179254 Maybridge4_001785 Cc1cc(C)c2c3NC(=O)CN(C(=O)c3sc2n1)c4ccccc4C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B04 compound treatment 33680.0 -8680.0 -0.5 33320.0 -12200.0 -0.93 -1.0105 -0.9589 1701942 Maybridge4_001786 COc1ccc(cc1)N2C(=O)Cc3ccc(OC)cc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B05 compound treatment 46960.0 4600.0 0.27 55200.0 9650.0 0.73 0.7047 0.9066 3179255 Maybridge4_001787 Clc1ccc(cc1)n2c(=N)c3cnc(nc3[nH]c2=O)N4CCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B06 compound treatment 38440.0 -3920.0 -0.23 43560.0 -1990.0 -0.15 -0.2674 -0.9801 1588538 Maybridge4_001788 Cc1oc2cc(O)ccc2c(=O)c1Oc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B07 compound treatment 4560.0 -37800.0 -2.19 7480.0 -38100.0 -2.88 -3.5865 -0.9908 3179256 Maybridge4_001789 COc1ccc(cc1)n/2c(cs\c2=N/Cc3cccnc3)c4cccc(OC)c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B08 compound treatment 45920.0 3560.0 0.21 53560.0 8010.0 0.61 0.5743 0.8971 3179257 Maybridge4_001790 O=C(c1ccccc1)c2cccc(NC=C3C(=O)NC(=O)NC3=O)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B09 compound treatment 46120.0 3760.0 0.22 47760.0 2210.0 0.17 0.272 0.9915 1289329 Maybridge4_001791 O=C1C(=C(c2ccccc2)S(=O)(=O)c3ccccc13)Cc4ccc(cc4)c5nnn[nH]5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B10 compound treatment 39240.0 -3120.0 -0.18 46320.0 768.0 0.06 -0.0869 -0.4572 1270319 Maybridge4_001792 O=C(c1ccccn1)c2ccc3ccccc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B11 compound treatment 18360.0 -24000.0 -1.39 20400.0 -25200.0 -1.9 -2.3297 -0.9881 1356935 Maybridge4_001793 C1C2CC3CC1CC(C2)(C3)c4cn5ccccc5n4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B12 compound treatment 32400.0 -9960.0 -0.58 36480.0 -9070.0 -0.69 -0.8938 -0.9963 1489551 Maybridge4_001794 Cc1cc(c(Cl)cc1Cl)S(=O)(=O)N2CCC(CC2)NC(=O)Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B13 compound treatment 44000.0 1640.0 0.09 49440.0 3890.0 0.29 0.2751 0.8899 3063861 Maybridge4_001795 CC(=O)O[C@@H]1[C@H]2CO[C@H](O2)[C@H](OC(=O)C)[C@H]1OC(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B14 compound treatment 43840.0 1480.0 0.09 46000.0 448.0 0.03 0.0844 0.9178 1649672 Maybridge4_001796 COc1cc(C(=O)CCC(=O)O)c(OC)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B15 compound treatment 42880.0 516.0 0.03 53000.0 7450.0 0.56 0.4198 0.7436 1471910 Maybridge4_001797 Cc1ccc(NC(=O)N2C(=O)C3(OCCO3)c4ccccc24)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B16 compound treatment 32080.0 -10300.0 -0.6 36480.0 -9070.0 -0.69 -0.9069 -0.9975 1205899 Maybridge4_001798 CCOC(=O)C1=C(C)N(C)C(=O)N(C)C1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B17 compound treatment 44680.0 2320.0 0.13 50000.0 4450.0 0.34 0.3329 0.9187 3063863 Maybridge4_001799 CC(=O)Nc1ccc2oc(cc(=O)c2c1)c3ccc(C#N)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B18 compound treatment 37240.0 -5120.0 -0.3 45840.0 288.0 0.02 -0.1945 -0.6535 3179258 Maybridge4_001800 Cc1c(sc2nc(C)cc(C)c12)C(=O)NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B19 compound treatment 43960.0 1600.0 0.09 50880.0 5330.0 0.4 0.3505 0.8473 3063864 Maybridge4_001801 CC(O)/C=C\c1cc[n+](C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B20 compound treatment 39400.0 -2960.0 -0.17 47560.0 2010.0 0.15 -0.014 -0.0609 3179259 Maybridge4_001802 O=C(NC(=S)NC1(CC2CC3CC(C2)C1)C3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B21 compound treatment 48600.0 6240.0 0.36 47080.0 1530.0 0.12 0.3372 0.889 1176828 Maybridge4_001803 COC(=O)C1C(C(C(=O)OC)S(=O)(=O)CS1(=O)=O)c2ccc(OC)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B22 compound treatment 26680.0 -15700.0 -0.91 31720.0 -13800.0 -1.05 -1.3829 -0.9975 1288189 Maybridge4_001804 COC(=O)C1=C(C)NC(=C(C1)C(=O)OC)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B23 mock treatment 47920.0 5560.0 0.32 49640.0 4090.0 0.31 0.4464 0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 B24 mock treatment 44360.0 2000.0 0.12 54520.0 8970.0 0.68 0.5618 0.8158 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C01 compound treatment 47960.0 5600.0 0.32 53040.0 7490.0 0.57 0.63 0.9649 3179260 Maybridge4_001805 O=S(=O)(NCC1COc2ccccc2O1)c3ccc(s3)S(=O)(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C02 compound treatment 32840.0 -9520.0 -0.55 37400.0 -8150.0 -0.62 -0.8265 -0.9984 3063865 Maybridge4_001806 Fc1ccc(cc1)C2C3CCc4ccccc4C3=NN2C(=O)c5ccco5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C03 compound treatment 38160.0 -4200.0 -0.24 40320.0 -5230.0 -0.4 -0.4523 -0.9727 3179353 Maybridge4_001807 COc1ccc(cc1OC)C(=O)NCc2ccc(C#N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C04 compound treatment 13240.0 -29100.0 -1.69 16680.0 -28900.0 -2.19 -2.7385 -0.9918 3063866 Maybridge4_001808 O=C(Oc1c(c2ccccc2)c(=O)n3CCc4cccc1c43)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C05 compound treatment 25760.0 -16600.0 -0.96 26400.0 -19200.0 -1.45 -1.7053 -0.9802 3179354 Maybridge4_001809 FC(F)(F)c1ccc(cc1)c2nnc(SCc3ccncc3)n2Cc4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C06 compound treatment 2120.0 -40200.0 -2.33 2280.0 -43300.0 -3.28 -3.9648 -0.9861 3063867 Maybridge4_001810 CCOC(=O)c1nnn2c1nc(Sc3nc4ccccc4o3)c5ccccc52 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C07 compound treatment 27640.0 -14700.0 -0.85 32080.0 -13500.0 -1.02 -1.3243 -0.9961 3179355 Maybridge4_001811 COc1cccc(Cc2nnc(o2)c3c(C)onc3c4ccccc4)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C08 compound treatment 520.0 -41800.0 -2.42 480.0 -45100.0 -3.41 -4.1267 -0.986 3179356 Maybridge4_001812 C=CCn1c(=S)sc2c(Sc3nnc(o3)c4ccco4)ncnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C09 compound treatment 30000.0 -12400.0 -0.72 33760.0 -11800.0 -0.89 -1.1377 -0.9941 3063868 Maybridge4_001813 Clc1ccc(Cn2c(=O)n(Cc3ccc(Cl)cc3)c4ccccc4c2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C10 compound treatment 36680.0 -5680.0 -0.33 42080.0 -3470.0 -0.26 -0.4187 -0.9938 3179357 Maybridge4_001814 Nc1nc(SCC(=O)NC(=O)Nc2ccccc2)ncc1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C11 compound treatment 10280.0 -32100.0 -1.86 10400.0 -35200.0 -2.66 -3.1959 -0.9846 2099392 Maybridge4_001815 Cc1nc2ccc(F)cc2c3N(CCc31)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C12 compound treatment 37560.0 -4800.0 -0.28 39960.0 -5590.0 -0.42 -0.4961 -0.9793 3179358 Maybridge4_001816 C=CCSc1ncc2c(=S)[nH]c(=S)[nH]c2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C13 compound treatment 40880.0 -1480.0 -0.09 42680.0 -2870.0 -0.22 -0.2145 -0.9176 3179359 Maybridge4_001817 Cc1cc(C)c2c(n1)sc3c(SCC(=O)c4ccc(Br)cc4)ncnc32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C14 compound treatment 39760.0 -2600.0 -0.15 44520.0 -1030.0 -0.08 -0.1619 -0.9531 3063869 Maybridge4_001818 C=CCn1nc2sc3ccccc3n2c(=O)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C15 compound treatment 39040.0 -3320.0 -0.19 43080.0 -2470.0 -0.19 -0.2685 -0.9999 3179360 Maybridge4_001819 COc1ccc(Nc2ncnc3n(Cc4ccccc4Cl)nnc23)c(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C16 compound treatment 32200.0 -10200.0 -0.59 33480.0 -12100.0 -0.91 -1.0626 -0.9774 3063871 Maybridge4_001820 CCOC(=O)c1c(C)c(C)sc1NC(=S)N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C17 compound treatment 11560.0 -30800.0 -1.78 16480.0 -29100.0 -2.2 -2.818 -0.9946 3179361 Maybridge4_001821 CCOC(=O)c1nnn2c1nc(N3CCN(CC3)c4ccccc4)c5ccccc52 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C18 compound treatment 13520.0 -28800.0 -1.67 23080.0 -22500.0 -1.7 -2.3845 -1.0 3063872 Maybridge4_001822 Cc1cc(C)c2c(=O)n(sc2n1)C(=O)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C19 compound treatment 25400.0 -17000.0 -0.98 30840.0 -14700.0 -1.11 -1.4824 -0.9981 3179362 Maybridge4_001823 COc1ccc(cc1)C2C(=C(N)N3CCc4cc(OC)c(OC)cc4C3=C2C#N)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C20 compound treatment 44240.0 1880.0 0.11 49880.0 4330.0 0.33 0.3085 0.8938 3063873 Maybridge4_001824 CNC(=O)NC(=O)Cn1cnc2sc(cc2c1=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C21 compound treatment 36000.0 -6360.0 -0.37 45000.0 -553.0 -0.04 -0.2903 -0.7823 3179363 Maybridge4_001825 COc1cc2CCN3C(N(N=C3C(=O)c4cccs4)c5ccccc5)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C22 compound treatment 35000.0 -7360.0 -0.43 41080.0 -4470.0 -0.34 -0.5411 -0.9934 3063874 Maybridge4_001826 Fc1ccc(/C=N/N2C(=O)/C(=C/c3ccco3)/N=C2c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C23 mock treatment 45760.0 3400.0 0.2 47480.0 1930.0 0.15 0.2423 0.9892 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 C24 mock treatment 46760.0 4400.0 0.25 52920.0 7370.0 0.56 0.5744 0.937 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D01 compound treatment 28240.0 -14100.0 -0.82 35240.0 -10300.0 -0.78 -1.1306 -0.9997 3179364 Maybridge4_001827 CCOC(=O)CSc1nc(Nc2ccc(OC)cc2)c3cnc(nc3n1)N(CC)CC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D02 compound treatment 42520.0 156.0 0.01 45760.0 208.0 0.02 0.0175 0.9657 1016783 Maybridge4_001828 CSc1ncnc2[nH]cnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D03 compound treatment 25640.0 -16700.0 -0.97 33560.0 -12000.0 -0.91 -1.327 -0.9995 3179365 Maybridge4_001829 CCOC(=O)CSc1nc(Nc2ccccc2)c3cnc(nc3n1)N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D04 compound treatment 39640.0 -2720.0 -0.16 46600.0 1050.0 0.08 -0.0555 -0.3144 3063875 Maybridge4_001830 CCn1c(C)[n+](CC)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D05 compound treatment 30880.0 -11500.0 -0.67 28760.0 -16800.0 -1.27 -1.3693 -0.9544 3179366 Maybridge4_001831 Nc1c(C#N)c(cc2c3ccccc3oc(=O)c12)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D06 compound treatment 32960.0 -9400.0 -0.54 39480.0 -6070.0 -0.46 -0.7103 -0.9964 1156367 Maybridge4_001832 CC(=O)Oc1ccc2c(=O)c(Oc3ccc(Cl)cc3)c(C)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D07 compound treatment 43240.0 876.0 0.05 44600.0 -953.0 -0.07 -0.0151 -0.1711 3179367 Maybridge4_001833 CC(/C=N/N1C(=O)c2ccccc2C1=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D08 compound treatment 43040.0 676.0 0.04 42920.0 -2630.0 -0.2 -0.1132 -0.5574 3063876 Maybridge4_001834 COC(=O)c1sc(=S)sc1C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D09 compound treatment 20320.0 -22000.0 -1.28 23680.0 -21900.0 -1.66 -2.0738 -0.9918 1027030 Maybridge4_001835 Clc1ccc2OC(CC(=O)c2c1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D10 compound treatment 38160.0 -4200.0 -0.24 43120.0 -2430.0 -0.18 -0.3024 -0.9905 1567173 Maybridge4_001836 C=CCN1C(=O)NC2(CCCCC2)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D11 compound treatment 23680.0 -18700.0 -1.08 26800.0 -18800.0 -1.42 -1.7691 -0.9911 1014811 Maybridge4_001837 O=C(N(C(=O)c1ccccc1)C(=O)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D12 compound treatment 38400.0 -3960.0 -0.23 42520.0 -3030.0 -0.23 -0.3247 -1.0 1422860 Maybridge4_001838 O=C(Cc1ccccc1)NC2CCN(CC2)C(=O)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D13 compound treatment 44400.0 2040.0 0.12 41040.0 -4510.0 -0.34 -0.1581 -0.4375 3063327 Maybridge4_001839 CCOc1ccc2nc(S/C=C/C(=O)c3ccc(Cl)cc3)sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D14 compound treatment 18880.0 -23500.0 -1.36 18280.0 -27300.0 -2.06 -2.4218 -0.9795 1403045 Maybridge4_001840 COc1cc(c(OC)cc1C)c2cc(OC)c(C)cc2OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D15 compound treatment 37800.0 -4560.0 -0.26 41520.0 -4030.0 -0.31 -0.4028 -0.9974 1267535 Maybridge4_001841 OC(=O)C(Sc1ccccc1C(=O)O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D16 compound treatment 41760.0 -604.0 -0.03 37120.0 -8430.0 -0.64 -0.4761 -0.7447 3063328 Maybridge4_001842 CC(C)(C)[C@H]1COC(=N1)CC2=N[C@H](CO2)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D17 compound treatment 37920.0 -4440.0 -0.26 42920.0 -2630.0 -0.2 -0.323 -0.992 1035033 Maybridge4_001843 O=C(C1=NNCC1c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D18 compound treatment 38560.0 -3800.0 -0.22 39920.0 -5630.0 -0.43 -0.4573 -0.9528 1414609 Maybridge4_001844 CC(=O)Oc1ccc2c(=O)c(c3nc4ccccc4n3C)c(C)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D19 compound treatment 39800.0 -2560.0 -0.15 39400.0 -6150.0 -0.47 -0.4343 -0.8885 3063329 Maybridge4_001845 CC1=CC(=O)OC(C1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D20 compound treatment 39040.0 -3320.0 -0.19 39880.0 -5670.0 -0.43 -0.4398 -0.9346 1054135 Maybridge4_001846 CCc1c(O)nc2ccccn2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D21 compound treatment 40080.0 -2280.0 -0.13 43560.0 -1990.0 -0.15 -0.2002 -0.9979 1416442 Maybridge4_001847 CCN(CC)CCC1S(=O)(=O)CC(CS1(=O)=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D22 compound treatment 37360.0 -5000.0 -0.29 40960.0 -4590.0 -0.35 -0.4508 -0.9959 3179368 Maybridge4_001848 C(/N=C/c1cn(nc1c2ccccc2)c3ccccc3)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D23 mock treatment 44680.0 2320.0 0.13 46200.0 648.0 0.05 0.1295 0.9068 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 D24 mock treatment 47600.0 5240.0 0.3 51080.0 5530.0 0.42 0.5104 0.9875 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E01 compound treatment 45600.0 3240.0 0.19 53120.0 7570.0 0.57 0.5376 0.892 3063330 Maybridge4_001849 O=C(Nc1cccs1)N2CCN(CC2)C(=O)C3CCCO3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E02 compound treatment 39520.0 -2840.0 -0.16 41200.0 -4350.0 -0.33 -0.3495 -0.9487 3179369 Maybridge4_001850 Clc1ccc(NC(=O)N2N=C3C(CCc4ccccc34)C2c5cccs5)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E03 compound treatment 36680.0 -5680.0 -0.33 40320.0 -5230.0 -0.4 -0.5129 -0.9958 3063331 Maybridge4_001851 CC(C)(C)c1cc(C(=O)NCc2ccc(C#N)cc2)n(Cc3ccccc3)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E04 compound treatment 32120.0 -10200.0 -0.59 37160.0 -8390.0 -0.64 -0.8689 -0.9994 3179370 Maybridge4_001852 C1Cc2ccccc2N1c3nnc(c4ccccc4)c(n3)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E05 compound treatment 23600.0 -18800.0 -1.09 26520.0 -19000.0 -1.44 -1.7874 -0.9904 3179371 Maybridge4_001853 Cn1nc(cc1C(F)(F)F)c2ccc(s2)S(=O)(=O)N3CCCN(CC3)C(=O)OC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E06 compound treatment 1840.0 -40500.0 -2.35 2120.0 -43400.0 -3.29 -3.9849 -0.9864 3063332 Maybridge4_001854 CCOC(=O)c1nnn2c1nc(Sc3nnc(c4ccncc4)n3C)c5ccccc52 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E07 compound treatment 43960.0 1600.0 0.09 41760.0 -3790.0 -0.29 -0.1376 -0.4562 3179372 Maybridge4_001855 Cc1ccc(cc1)S(=O)(=O)NC(=O)N2CCCN(CC2)C(=O)OC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E08 compound treatment 44240.0 1880.0 0.11 43360.0 -2190.0 -0.17 -0.0405 -0.2041 1566406 Maybridge4_001856 CNc1nc(=S)[nH]c2sc3CCCCc3c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E09 compound treatment 43360.0 996.0 0.06 45880.0 328.0 0.02 0.0583 0.9288 3179373 Maybridge4_001857 OC[C@@H]1O[C@@H](C[C@H]1O)n2cnc3c(=O)[nH]cnc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E10 compound treatment 42720.0 356.0 0.02 42480.0 -3070.0 -0.23 -0.1499 -0.6418 3063334 Maybridge4_001858 COc1ccc(Nc2ncc(C#N)c(N)n2)c(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E11 compound treatment 35000.0 -7360.0 -0.43 34760.0 -10800.0 -0.82 -0.8793 -0.9541 3179374 Maybridge4_001859 CCNc1nc(=S)[nH]c2n(ncc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E12 compound treatment 38320.0 -4040.0 -0.23 40360.0 -5190.0 -0.39 -0.4436 -0.9694 3063335 Maybridge4_001860 CCN(CC)c1ncc2c(=S)[nH]c(=S)[nH]c2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E13 compound treatment 20440.0 -21900.0 -1.27 19240.0 -26300.0 -1.99 -2.3065 -0.9764 3179375 Maybridge4_001861 Cc1cc(C)c2c(n1)sc3c(Sc4nnc(o4)c5ccncc5)ncnc32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E14 compound treatment 3920.0 -38400.0 -2.23 5440.0 -40100.0 -3.04 -3.722 -0.9884 3179376 Maybridge4_001862 CCOC(=O)N1CCc2c(C1)sc3ncn(Cc4ccc(Cl)cc4)c(=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E15 compound treatment 13000.0 -29400.0 -1.7 12360.0 -33200.0 -2.51 -2.9796 -0.982 3063336 Maybridge4_001863 Clc1ccccc1C2C3CCc4ccccc4C3=NN2C(=S)NCC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E16 compound treatment 26000.0 -16400.0 -0.95 30000.0 -15600.0 -1.18 -1.5028 -0.9942 1616264 Maybridge4_001864 CC1=NN(C(=O)C1)c2ncnc3sc4CCCCc4c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E17 compound treatment 36760.0 -5600.0 -0.32 35160.0 -10400.0 -0.79 -0.7858 -0.9234 3179377 Maybridge4_001865 CCOC(=O)c1nnn2c1nc(N(Cc3ccccc3)Cc4ccccc4)c5ccccc52 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E18 compound treatment 40000.0 -2360.0 -0.14 39920.0 -5630.0 -0.43 -0.3983 -0.8895 3063337 Maybridge4_001866 NNC(=O)/C(=C\c1ccccc1)/NC(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E19 compound treatment 39880.0 -2480.0 -0.14 37320.0 -8230.0 -0.62 -0.5424 -0.8481 3179378 Maybridge4_001867 Cc1ccc(Cc2nn3c(nn(c4ccc(Cl)cc4)c3nc2=O)C(=O)c5cccs5)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E20 compound treatment 24760.0 -17600.0 -1.02 32840.0 -12700.0 -0.96 -1.4016 -0.9996 3063338 Maybridge4_001868 Fc1ccc(Cn2nc3CSc4ccccc4-n3c2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E21 compound treatment 18480.0 -23900.0 -1.38 23920.0 -21600.0 -1.64 -2.1363 -0.9965 3063339 Maybridge4_001869 Cc1ccc2nc(C)c3CCN(c3c2c1)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E22 compound treatment 36800.0 -5560.0 -0.32 37960.0 -7590.0 -0.57 -0.6343 -0.9626 3179379 Maybridge4_001870 Fc1ccc(/C=C\2/N=C(N(CC(=O)c3ccco3)C2=O)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E23 mock treatment 49240.0 6880.0 0.4 49360.0 3810.0 0.29 0.4855 0.9874 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 E24 mock treatment 45280.0 2920.0 0.17 43960.0 -1590.0 -0.12 0.0342 0.165 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F01 compound treatment 41520.0 -844.0 -0.05 50880.0 5330.0 0.4 0.2506 0.6169 3179475 Maybridge4_001871 Cc1cc(nc2oc3C(=O)N(CC(=O)Nc3c12)c4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F02 compound treatment 37720.0 -4640.0 -0.27 38200.0 -7350.0 -0.56 -0.5838 -0.9444 1429948 Maybridge4_001872 CC1(C)C(NC(=O)C2CCCCC2)[C@]3(C)CCC1C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F03 compound treatment 38800.0 -3560.0 -0.21 39960.0 -5590.0 -0.42 -0.4453 -0.9455 3179476 Maybridge4_001873 CCN(CC)c1ncc2c(NCc3ccccc3)nc(SCc4ccccc4)nc2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F04 compound treatment 45400.0 3040.0 0.18 49240.0 3690.0 0.28 0.3218 0.9752 1050962 Maybridge4_001874 NC(=O)CCCCC1CCSS1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F05 compound treatment 38560.0 -3800.0 -0.22 44040.0 -1510.0 -0.11 -0.2368 -0.9535 3179477 Maybridge4_001875 O=C(CN1CCc2ccccc12)Nc3scc4c3c(=O)oc5ccccc45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F06 compound treatment 42000.0 -364.0 -0.02 45880.0 328.0 0.02 0.0026 0.0807 3063341 Maybridge4_001876 CC1(C)C2CCC1(C)c3noc(c23)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F07 compound treatment 42040.0 -324.0 -0.02 43280.0 -2270.0 -0.17 -0.1349 -0.7796 1040822 Maybridge4_001877 Cc1ccc(NC(=O)N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F08 compound treatment 14640.0 -27700.0 -1.61 19280.0 -26300.0 -1.99 -2.542 -0.9944 1502018 Maybridge4_001878 COc1ccc2oc(cc(=O)c2c1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F09 compound treatment 37720.0 -4640.0 -0.27 35640.0 -9910.0 -0.75 -0.7208 -0.9043 3063363 Maybridge4_001879 O=C1/C(=C/c2ccc(cc2)c3nnn[nH]3)/C(Oc4ccccc14)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F10 compound treatment 39480.0 -2880.0 -0.17 42120.0 -3430.0 -0.26 -0.3019 -0.9772 3063364 Maybridge4_001880 CC1(C)NC(=O)N(CC=C)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F11 compound treatment 29360.0 -13000.0 -0.75 26800.0 -18800.0 -1.42 -1.5364 -0.9561 3063365 Maybridge4_001881 Clc1ccccc1CNC(=S)NC2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F12 compound treatment 27520.0 -14800.0 -0.86 35120.0 -10400.0 -0.79 -1.1665 -0.9991 3063366 Maybridge4_001882 Fc1ccc(cc1)N(Cc2ccc(Br)cc2)C(=O)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F13 compound treatment 3680.0 -38700.0 -2.24 5600.0 -40000.0 -3.02 -3.7232 -0.9891 1687915 Maybridge4_001883 CC1(C)CC(=O)C=C(C1)Sc2nc3ccccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F14 compound treatment 36680.0 -5680.0 -0.33 40680.0 -4870.0 -0.37 -0.4936 -0.9984 3063367 Maybridge4_001884 C[n+]1ccc(CCc2cc[n+](C)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F15 compound treatment 42040.0 -324.0 -0.02 43440.0 -2110.0 -0.16 -0.1263 -0.7847 1612566 Maybridge4_001885 CCC(=O)N1N(C(=O)CC)c2cc(Cl)ccc2-n3c1nn(C(=O)CC)c3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F16 compound treatment 18400.0 -24000.0 -1.39 17320.0 -28200.0 -2.14 -2.4929 -0.9782 1406161 Maybridge4_001886 CC(=O)Oc1c(I)c(=O)n(C)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F17 compound treatment 36840.0 -5520.0 -0.32 40640.0 -4910.0 -0.37 -0.4892 -0.9972 3179478 Maybridge4_001887 CCSC(=O)NC1CCCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F18 compound treatment 40040.0 -2320.0 -0.13 39280.0 -6270.0 -0.47 -0.4309 -0.8732 3179479 Maybridge4_001888 C1C(=CC(=NN=C1c2ccccc2)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F19 compound treatment 37960.0 -4400.0 -0.26 40840.0 -4710.0 -0.36 -0.4326 -0.9865 1002179 Maybridge4_001889 Clc1ccc(cc1)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F20 compound treatment 37600.0 -4760.0 -0.28 46240.0 688.0 0.05 -0.1584 -0.5638 3063368 Maybridge4_001890 CCC(C)Sc1nnc(S)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F21 compound treatment 28000.0 -14400.0 -0.83 30920.0 -14600.0 -1.11 -1.3716 -0.9901 3179480 Maybridge4_001891 COC(=O)/C(=C/c1ccccc1)/c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F22 compound treatment 44960.0 2600.0 0.15 45520.0 -32.5 0.0 0.1046 0.6954 1172572 Maybridge4_001892 O=c1[nH]cc(NCc2ccccc2)c(=O)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F23 mock treatment 45120.0 2760.0 0.16 51000.0 5450.0 0.41 0.4045 0.9147 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 F24 mock treatment 43240.0 876.0 0.05 49840.0 4290.0 0.32 0.2654 0.8079 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G01 compound treatment 43600.0 1240.0 0.07 46000.0 448.0 0.03 0.0746 0.9415 3179481 Maybridge4_001893 CCOC(=O)N1CCC(CC1)NC(=O)CCCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G02 compound treatment 29600.0 -12800.0 -0.74 35000.0 -10600.0 -0.8 -1.0877 -0.9993 3179482 Maybridge4_001894 O=C1CSC2=NC3=C(CCc4ccccc34)C(N12)c5cccs5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G03 compound treatment 39440.0 -2920.0 -0.17 42240.0 -3310.0 -0.25 -0.2971 -0.9818 3063369 Maybridge4_001895 CCOC(=O)c1ncn(Cc2ccccc2)c1N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G04 compound treatment 43520.0 1160.0 0.07 39760.0 -5790.0 -0.44 -0.2627 -0.5922 3063370 Maybridge4_001896 S=c1[nH]nc(Cn2nnc3ccccc23)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G05 compound treatment 38080.0 -4280.0 -0.25 39400.0 -6150.0 -0.47 -0.5048 -0.9566 3179483 Maybridge4_001897 COc1cccc(Cc2nnc(o2)c3ccc(s3)c4cccs4)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G06 compound treatment 21040.0 -21300.0 -1.24 24760.0 -20800.0 -1.57 -1.9865 -0.9928 3063371 Maybridge4_001898 Cn1nc2c3ccccc3n(Cc4ccccc4)c2nc1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G07 compound treatment 33480.0 -8880.0 -0.51 41160.0 -4390.0 -0.33 -0.5991 -0.9776 3179484 Maybridge4_001899 CCOC(=O)c1cnn(C(=O)Cc2cccc(OC)c2)c1N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G08 compound treatment 33400.0 -8960.0 -0.52 37480.0 -8070.0 -0.61 -0.7993 -0.9967 1696254 Maybridge4_001900 COc1cc(OC)c2nc(C)c3CCSc3c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G09 compound treatment 23600.0 -18800.0 -1.09 27680.0 -17900.0 -1.35 -1.7253 -0.9941 3179485 Maybridge4_001901 CC(=O)Nc1ccccc1OCC2CC(=NO2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G10 compound treatment 31920.0 -10400.0 -0.61 36880.0 -8670.0 -0.66 -0.892 -0.9992 3179486 Maybridge4_001902 C1Sc2nnc(c3ccccc3)n2N=C1c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G11 compound treatment 37280.0 -5080.0 -0.29 37320.0 -8230.0 -0.62 -0.6489 -0.9415 3063373 Maybridge4_001903 S=c1nc(Nc2ccccc2)c3cnn(c4ccccc4)c3[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G12 compound treatment 31600.0 -10800.0 -0.62 36400.0 -9150.0 -0.69 -0.9308 -0.9986 3179487 Maybridge4_001904 CN1CCN(CC1)c2ncc3c(=S)[nH]c(=S)[nH]c3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G13 compound treatment 11840.0 -30500.0 -1.77 6920.0 -38600.0 -2.92 -3.3183 -0.971 3063374 Maybridge4_001905 CCn1c(Sc2ncnc3c2sc4nc(C)cc(C)c43)nnc1c5cccs5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G14 compound treatment 28960.0 -13400.0 -0.78 31400.0 -14200.0 -1.07 -1.3066 -0.9875 3179488 Maybridge4_001906 CCOC(=O)N1CCc2c(C(=O)OCC)c(NC(=S)N3CCc4ccccc34)sc2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G15 compound treatment 10960.0 -31400.0 -1.82 12480.0 -33100.0 -2.5 -3.0567 -0.9877 3179489 Maybridge4_001907 CCNC(=S)N1N=C2C(CCc3ccccc23)C1c4ccc(F)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G16 compound treatment 52320.0 9960.0 0.58 54680.0 9130.0 0.69 0.8964 0.996 1303898 Maybridge4_001908 CC1=NN(C(=O)C1)c2nc3ccccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G17 compound treatment 31400.0 -11000.0 -0.64 31320.0 -14200.0 -1.08 -1.2109 -0.9683 3063375 Maybridge4_001909 CCOC(=O)C1=NN(C2N1CCc3cc(OC)c(OC)cc23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G18 compound treatment 15560.0 -26800.0 -1.55 16440.0 -29100.0 -2.2 -2.6563 -0.9853 3179490 Maybridge4_001910 COc1cc(/C=C\2/N=C(N(C)C2=O)c3ccccc3)cc(OC)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G19 compound treatment 24200.0 -18200.0 -1.05 27280.0 -18300.0 -1.38 -1.7222 -0.9909 3063377 Maybridge4_001911 Cc1c(C)c(=O)n(Cc2ccc(Br)cc2)c(=O)n1Cc3ccc(Br)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G20 compound treatment 27720.0 -14600.0 -0.85 30920.0 -14600.0 -1.11 -1.3831 -0.9913 3179491 Maybridge4_001912 O=C(Cn1nc2CSc3ccccc3-n2c1=O)NC(=O)Nc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G21 compound treatment 34560.0 -7800.0 -0.45 33960.0 -11600.0 -0.88 -0.9402 -0.9524 3179492 Maybridge4_001913 CCOC(=O)c1sc2nc(C)cc(C)c2c1NC(=O)Nc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G22 compound treatment 22720.0 -19600.0 -1.14 24520.0 -21000.0 -1.59 -1.9305 -0.9865 1150256 Maybridge4_001914 N(c1ccccc1)c2ncnc3sc(cc23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G23 mock treatment 43720.0 1360.0 0.08 45880.0 328.0 0.02 0.0731 0.8871 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 G24 mock treatment 39640.0 -2720.0 -0.16 42840.0 -2710.0 -0.21 -0.2568 -0.9915 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H01 compound treatment 48960.0 6600.0 0.38 47840.0 2290.0 0.17 0.3927 0.9359 3179493 Maybridge4_001915 COc1cc(cc(OC)c1OC)c2nnc(SCC(=O)c3ccco3)n2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H02 compound treatment 44000.0 1640.0 0.09 39840.0 -5710.0 -0.43 -0.2387 -0.5393 1202312 Maybridge4_001916 Clc1ccc(OC2CN(C2)C(=O)N3CC(C3)Oc4ccc(Cl)cc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H03 compound treatment 36800.0 -5560.0 -0.32 43880.0 -1670.0 -0.13 -0.3175 -0.9167 3179494 Maybridge4_001917 O=C(CN1CCc2ccccc12)Nc3nnc(s3)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H04 compound treatment 40440.0 -1920.0 -0.11 45560.0 7.5 0.0 -0.0784 -0.7035 1178262 Maybridge4_001918 COc1ccc(cc1)c2nc3cc4Nc5ccccc5Oc4cc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H05 compound treatment 32240.0 -10100.0 -0.59 43720.0 -1830.0 -0.14 -0.5128 -0.8509 3063402 Maybridge4_001919 O=C(Nc1scc2c1c(=O)oc3ccccc23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H06 compound treatment 42600.0 236.0 0.01 36960.0 -8590.0 -0.65 -0.4502 -0.6921 3179495 Maybridge4_001920 FC(F)(F)C(NC(=O)c1cccnc1)(N2CCCC2=O)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H07 compound treatment 36280.0 -6080.0 -0.35 37360.0 -8190.0 -0.62 -0.6877 -0.9642 1117011 Maybridge4_001921 COc1cccc(NC(=O)N)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H08 compound treatment 37080.0 -5280.0 -0.31 44400.0 -1150.0 -0.09 -0.2782 -0.8738 3063403 Maybridge4_001922 NC(=O)c1cc(Cl)c(Cl)cc1C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H09 compound treatment 25760.0 -16600.0 -0.96 32960.0 -12600.0 -0.95 -1.3542 -1.0 3179496 Maybridge4_001923 O[C@H]1[C@@H](Oc2ccccc2C1=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H10 compound treatment 39840.0 -2520.0 -0.15 37040.0 -8510.0 -0.64 -0.559 -0.8461 3063404 Maybridge4_001924 COc1ncnc(OC)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H11 compound treatment 13280.0 -29100.0 -1.69 16640.0 -28900.0 -2.19 -2.739 -0.9917 1558852 Maybridge4_001925 CC1=C(C(C2=C(N1)c3ccccc3C2=O)c4ccccc4)C(=O)Nc5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H12 compound treatment 32920.0 -9440.0 -0.55 32600.0 -13000.0 -0.98 -1.0802 -0.962 1698244 Maybridge4_001926 O=C(Cc1ccccc1)NC2CCN(CC2)C(=O)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H13 compound treatment 28520.0 -13800.0 -0.8 29920.0 -15600.0 -1.18 -1.4039 -0.9821 1372400 Maybridge4_001927 O=c1c(c[nH]c2ccccc12)c3nnnn3c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H14 compound treatment 35240.0 -7120.0 -0.41 35040.0 -10500.0 -0.8 -0.8545 -0.9533 3179497 Maybridge4_001928 N1[C@H]([C@H](N=C1c2ccccc2)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H15 compound treatment 29040.0 -13300.0 -0.77 28600.0 -17000.0 -1.28 -1.4532 -0.9704 3063405 Maybridge4_001929 CO[C@H]1O[C@H](COC(=O)c2ccccc2)[C@@H](O)[C@H](O)[C@H]1OC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H16 compound treatment 35040.0 -7320.0 -0.42 37760.0 -7790.0 -0.59 -0.7171 -0.9869 1081881 Maybridge4_001930 COC(=O)CSc1nc2ccccc2[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H17 compound treatment 33200.0 -9160.0 -0.53 34800.0 -10800.0 -0.81 -0.9509 -0.9786 3063406 Maybridge4_001931 CC(C)N(C(C)C)C(=O)NCc1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H18 compound treatment 35880.0 -6480.0 -0.38 37640.0 -7910.0 -0.6 -0.6891 -0.9747 3179498 Maybridge4_001932 Clc1ccc(cc1)c2nc(SCc3ccccc3)[nH]c(=S)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H19 compound treatment 37040.0 -5320.0 -0.31 38320.0 -7230.0 -0.55 -0.6052 -0.9632 3063407 Maybridge4_001933 OC(=O)c1cc(F)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H20 compound treatment 33000.0 -9360.0 -0.54 32640.0 -12900.0 -0.98 -1.0747 -0.9614 1198061 Maybridge4_001934 CC(Oc1ccc(Cl)cc1Cl)c2n[nH]c(=S)n2CC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H21 compound treatment 38200.0 -4160.0 -0.24 37360.0 -8190.0 -0.62 -0.6091 -0.9154 3179499 Maybridge4_001935 FC(F)(F)C(NC1CCCCC1)(NC(=O)c2ccccc2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H22 compound treatment 36080.0 -6280.0 -0.36 37480.0 -8070.0 -0.61 -0.6895 -0.9694 1345621 Maybridge4_001936 O=c1[nH][nH]c(=O)n1CCCc2cc3cccc4ccc5cccc2c5c43 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H23 mock treatment 42080.0 -284.0 -0.02 41600.0 -3950.0 -0.3 -0.2232 -0.7448 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 H24 mock treatment 40080.0 -2280.0 -0.13 46160.0 608.0 0.05 -0.061 -0.4358 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I01 compound treatment 34520.0 -7840.0 -0.45 39760.0 -5790.0 -0.44 -0.6314 -0.9998 3179500 Maybridge4_001937 NC(=O)c1ccccc1NCC(=O)c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I02 compound treatment 40240.0 -2120.0 -0.12 48400.0 2850.0 0.22 0.0654 0.2635 1786031 Maybridge4_001938 S=c1[nH]nc(Cc2ccccc2)n1Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I03 compound treatment 40560.0 -1800.0 -0.1 44600.0 -953.0 -0.07 -0.1249 -0.9836 1416652 Maybridge4_001939 Cc1ccc(cc1)S(=O)(=O)NC(=O)Nc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I04 compound treatment 42480.0 116.0 0.01 43360.0 -2190.0 -0.17 -0.1126 -0.6779 3179586 Maybridge4_001940 CNC(=O)NC(=O)CSc1nnc(Cc2ccccc2)n1c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I05 compound treatment 37040.0 -5320.0 -0.31 41440.0 -4110.0 -0.31 -0.4382 -1.0 3063409 Maybridge4_001941 Cn1cc(cn1)S(=O)(=O)Nc2ccc(Oc3c(Cl)cccc3Cl)nc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I06 compound treatment 28640.0 -13700.0 -0.8 33960.0 -11600.0 -0.88 -1.1827 -0.9988 3179587 Maybridge4_001942 Clc1ccccc1CC(C(=O)N2CCc3ccccc23)C(=O)N4CCc5ccccc45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I07 compound treatment 27400.0 -15000.0 -0.87 36280.0 -9270.0 -0.7 -1.1093 -0.9945 3063410 Maybridge4_001943 CCOC(=O)c1cnn(C(=O)c2ccc(cc2)n3c(C)ccc3C)c1N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I08 compound treatment 39760.0 -2600.0 -0.15 39720.0 -5830.0 -0.44 -0.4188 -0.8978 1500802 Maybridge4_001944 NC(=O)c1nnc2ccc(Cl)cc2c1N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I09 compound treatment 32040.0 -10300.0 -0.6 32800.0 -12800.0 -0.97 -1.1055 -0.9735 1103360 Maybridge4_001945 FC(F)(F)c1ccc(cc1)C(=O)CN2C(=O)c3ccccc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I10 compound treatment 37360.0 -5000.0 -0.29 39480.0 -6070.0 -0.46 -0.53 -0.9753 3179588 Maybridge4_001946 O=C(CSc1nnc2NCCCn12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I11 compound treatment 37200.0 -5160.0 -0.3 36000.0 -9550.0 -0.72 -0.7228 -0.9237 1721477 Maybridge4_001947 Cc1nn(c2NC3=C(C(c12)c4cccnc4)C(=O)CC(C)(C)C3)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I12 compound treatment 31520.0 -10800.0 -0.63 36800.0 -8750.0 -0.66 -0.9127 -0.9996 1444715 Maybridge4_001948 Cc1nc2cc(C)ccn2c1c3nnco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I13 compound treatment 27400.0 -15000.0 -0.87 35240.0 -10300.0 -0.78 -1.165 -0.9986 3063411 Maybridge4_001949 Cc1cc(C)c(C#N)c(Sc2ncnc3c2sc4nc(C)cc(C)c43)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I14 compound treatment 33760.0 -8600.0 -0.5 36840.0 -8710.0 -0.66 -0.8188 -0.9905 3179589 Maybridge4_001950 COc1ccc(cc1)n2c(n[nH]c2=S)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I15 compound treatment 16720.0 -25600.0 -1.49 21280.0 -24300.0 -1.84 -2.3497 -0.9945 3179590 Maybridge4_001951 CNC(=S)N1N=C2C(CCc3ccccc23)C1c4ccc(OC)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I16 compound treatment 33120.0 -9240.0 -0.54 31440.0 -14100.0 -1.07 -1.1341 -0.949 3063412 Maybridge4_001952 CCOC(=O)N1CCc2c(C1)sc3[nH]c(=S)n(c4ccccc4)c(=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I17 compound treatment 25600.0 -16800.0 -0.97 26800.0 -18800.0 -1.42 -1.6905 -0.9829 3179591 Maybridge4_001953 COc1cc2CCn3c(C(=O)c4cccs4)c(c(C#N)c3-c2cc1OC)c5ccc(C)cc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I18 compound treatment 27680.0 -14700.0 -0.85 30560.0 -15000.0 -1.13 -1.404 -0.9899 3063413 Maybridge4_001954 Fc1ccc(CN2C(=O)/C(=C\c3ccc(F)cc3)/N=C2c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I19 compound treatment 37960.0 -4400.0 -0.26 37800.0 -7750.0 -0.59 -0.5954 -0.9304 3179592 Maybridge4_001955 CCC(C)[C@H](NC(=O)c1ccco1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I20 compound treatment 24440.0 -17900.0 -1.04 26560.0 -19000.0 -1.44 -1.7509 -0.9873 3179593 Maybridge4_001956 COc1cccc(c1)C(=O)c2sc3nsc(SCc4ccccc4)c3c2N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I21 compound treatment 33520.0 -8840.0 -0.51 37360.0 -8190.0 -0.62 -0.8008 -0.9955 3063414 Maybridge4_001957 Cc1cc(C)c2c(N)c(sc2n1)c3nnc(SCC(=O)c4ccccc4)n3CC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I22 compound treatment 37360.0 -5000.0 -0.29 44240.0 -1310.0 -0.1 -0.2752 -0.8982 3179594 Maybridge4_001958 C=CCn1nc2CSc3ccccc3-n2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I23 mock treatment 39760.0 -2600.0 -0.15 46000.0 448.0 0.03 -0.0827 -0.535 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 I24 mock treatment 38120.0 -4240.0 -0.25 46520.0 968.0 0.07 -0.1221 -0.4758 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J01 compound treatment 44160.0 1800.0 0.1 45840.0 288.0 0.02 0.089 0.8369 3179595 Maybridge4_001959 CCOC(=O)CSc1nc(CN2c3ccccc3Sc4ccccc24)n[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J02 compound treatment 41160.0 -1200.0 -0.07 44520.0 -1030.0 -0.08 -0.1046 -0.9984 1402836 Maybridge4_001960 NS(=O)(=O)c1ccc(Cl)cc1Sc2ccccc2C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J03 compound treatment 21600.0 -20800.0 -1.2 30160.0 -15400.0 -1.17 -1.6745 -0.9999 3179596 Maybridge4_001961 CCOC(=O)Cn1c(nc(c1c2ccccc2)c3ccccc3)c4cccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J04 compound treatment 38960.0 -3400.0 -0.2 44240.0 -1310.0 -0.1 -0.2097 -0.9496 1114912 Maybridge4_001962 NNC(=O)CNC(=O)c1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J05 compound treatment 30880.0 -11500.0 -0.67 36840.0 -8710.0 -0.66 -0.9368 -1.0 3179597 Maybridge4_001963 Fc1ccc(COc2nc(cc(c3ccco3)c2C#N)c4cccs4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J06 compound treatment 34960.0 -7400.0 -0.43 39400.0 -6150.0 -0.47 -0.6326 -0.9992 3063348 Maybridge4_001964 FC(F)(F)C(NCc1ccccn1)(NC(=O)c2cccnc2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J07 compound treatment 27200.0 -15200.0 -0.88 33240.0 -12300.0 -0.93 -1.2802 -0.9996 3179598 Maybridge4_001965 COc1ccc(/N=C/c2cn(cc2\C=N\c3ccc(OC)cc3)c4ccc(OC)cc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J08 compound treatment 18640.0 -23700.0 -1.37 25040.0 -20500.0 -1.55 -2.0698 -0.9982 1550362 Maybridge4_001966 OC(=O)c1ccccc1NC(=O)OCC2c3ccccc3-c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J09 compound treatment 8800.0 -33600.0 -1.94 9760.0 -35800.0 -2.71 -3.2908 -0.9868 3179599 Maybridge4_001967 CC1(C)CC(=O)C=C(C1)Sc2nc3cc(Cl)ccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J10 compound treatment 34680.0 -7680.0 -0.45 35320.0 -10200.0 -0.77 -0.8625 -0.9654 1156147 Maybridge4_001968 COc1ccc2nc3n(C)c(=O)n(C)c(=O)c3cc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J11 compound treatment 13440.0 -28900.0 -1.68 14400.0 -31200.0 -2.36 -2.8524 -0.986 3179600 Maybridge4_001969 O=C1C2=C(NC(=S)NC2c3ccccc3)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J12 compound treatment 20840.0 -21500.0 -1.25 18680.0 -26900.0 -2.03 -2.3201 -0.9724 1727811 Maybridge4_001970 COc1cc(CCC(C)NC(=O)c2ccco2)ccc1OC(=O)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J13 compound treatment 18480.0 -23900.0 -1.38 21000.0 -24600.0 -1.86 -2.2926 -0.9895 3063350 Maybridge4_001971 COc1ccc(C#N)cc1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J14 compound treatment 32280.0 -10100.0 -0.58 32640.0 -12900.0 -0.98 -1.1042 -0.9697 1014022 Maybridge4_001972 O=S(=O)(Cc1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J15 compound treatment 36040.0 -6320.0 -0.37 35680.0 -9870.0 -0.75 -0.7875 -0.9462 3179601 Maybridge4_001973 Nc1n/c(=N\c2ccccc2)/n(c3ccccc3)c(=N)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J16 compound treatment 21200.0 -21200.0 -1.23 24040.0 -21500.0 -1.63 -2.0185 -0.9902 3063351 Maybridge4_001974 FC(F)(F)c1ccccc1/N=C/2\CCCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J17 compound treatment 39080.0 -3280.0 -0.19 35240.0 -10300.0 -0.78 -0.6865 -0.8544 3179602 Maybridge4_001975 COCOc1ccc(cc1OC)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J18 compound treatment 25280.0 -17100.0 -0.99 26880.0 -18700.0 -1.41 -1.6993 -0.9848 1465673 Maybridge4_001976 CC(Nc1ccccc1)(C#N)c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J19 compound treatment 15080.0 -27300.0 -1.58 15000.0 -30600.0 -2.31 -2.7531 -0.9828 3179603 Maybridge4_001977 c1ccc(cc1)c2nnc(o2)c3cccc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J20 compound treatment 34520.0 -7840.0 -0.45 37200.0 -8350.0 -0.63 -0.7684 -0.9869 1519121 Maybridge4_001978 CC(Oc1ccccc1c2ccccc2)c3n[nH]c(=S)n3c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J21 compound treatment 32160.0 -10200.0 -0.59 35600.0 -9950.0 -0.75 -0.9507 -0.9928 3063353 Maybridge4_001979 COC(NC(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J22 compound treatment 40960.0 -1400.0 -0.08 42800.0 -2750.0 -0.21 -0.2048 -0.9158 1009264 Maybridge4_001980 CC(NC(=O)C)c1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J23 mock treatment 38280.0 -4080.0 -0.24 41320.0 -4230.0 -0.32 -0.3938 -0.9889 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 J24 mock treatment 38120.0 -4240.0 -0.25 40320.0 -5230.0 -0.4 -0.4539 -0.9737 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K01 compound treatment 38160.0 -4200.0 -0.24 40040.0 -5510.0 -0.42 -0.4673 -0.9671 3179604 Maybridge4_001981 OC(=O)CSCC(=O)N1CCCN(CC1)c2ccc(cn2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K02 compound treatment 32160.0 -10200.0 -0.59 35760.0 -9790.0 -0.74 -0.9422 -0.9937 3063380 Maybridge4_001982 CCOC(=O)c1nnn2c1nc(SCC(=O)N)c3ccccc32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K03 compound treatment 9720.0 -32600.0 -1.89 13440.0 -32100.0 -2.43 -3.0561 -0.9923 3179605 Maybridge4_001983 COc1ccc(NC(=O)c2ccc(CN3CCS(=O)(=O)CC3)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K04 compound treatment 32720.0 -9640.0 -0.56 35240.0 -10300.0 -0.78 -0.9471 -0.9866 3063381 Maybridge4_001984 CNC(=O)NC(=O)CSc1nnc(c2ccncc2)n1Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K05 compound treatment 25440.0 -16900.0 -0.98 28040.0 -17500.0 -1.33 -1.6307 -0.989 3179606 Maybridge4_001985 S=C(NCC1CC(=NO1)c2ccccc2)NCc3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K06 compound treatment 29280.0 -13100.0 -0.76 33200.0 -12400.0 -0.94 -1.1972 -0.9946 3179607 Maybridge4_001986 CCOc1nc-2c(Cc3ccccc32)c(c4ccco4)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K07 compound treatment 28280.0 -14100.0 -0.82 31560.0 -14000.0 -1.06 -1.3259 -0.9917 3063383 Maybridge4_001987 Sc1nnc(Cc2ccsc2)n1Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K08 compound treatment 31800.0 -10600.0 -0.61 36600.0 -8950.0 -0.68 -0.912 -0.9987 3179608 Maybridge4_001988 O=c1[nH]c-2c(CCc3ccccc32)c(c1C#N)c4cccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K09 compound treatment 9760.0 -32600.0 -1.89 13160.0 -32400.0 -2.45 -3.0695 -0.9917 3063384 Maybridge4_001989 C=CCSc1c2CCCc2c(C#N)c3nc4ccccc4n13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K10 compound treatment 25560.0 -16800.0 -0.97 29200.0 -16400.0 -1.24 -1.5637 -0.9929 3179609 Maybridge4_001990 O=C(N1CCCn2c(SCc3ccccc3)nnc12)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K11 compound treatment 23120.0 -19200.0 -1.11 23600.0 -22000.0 -1.66 -1.9634 -0.9812 3063386 Maybridge4_001991 CCNC(=S)Nc1sc2CC(C)CCc2c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K12 compound treatment 29560.0 -12800.0 -0.74 30240.0 -15300.0 -1.16 -1.3441 -0.9767 3179610 Maybridge4_001992 Cc1sc2nc3SCC(=Nn3c(=O)c2c1C)c4ccc(F)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K13 compound treatment 26880.0 -15500.0 -0.9 29480.0 -16100.0 -1.22 -1.4946 -0.9888 3063387 Maybridge4_001993 CCOC(=O)c1oc2nc(cc(c3ccco3)c2c1N)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K14 compound treatment 27960.0 -14400.0 -0.83 33360.0 -12200.0 -0.92 -1.2427 -0.9987 3179611 Maybridge4_001994 C1Sc2ccccc2-n3c(nnc13)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K15 compound treatment 29840.0 -12500.0 -0.73 28880.0 -16700.0 -1.26 -1.4055 -0.9655 3179694 Maybridge4_001995 CCOC(=O)c1nnn2c1n(C)c(=O)c3ccccc32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K16 compound treatment 27240.0 -15100.0 -0.88 28200.0 -17400.0 -1.31 -1.5484 -0.9806 3063389 Maybridge4_001996 O=c1c(nnc2sc3ccccc3n12)N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K17 compound treatment 25080.0 -17300.0 -1.0 26480.0 -19100.0 -1.44 -1.7289 -0.984 3179695 Maybridge4_001997 CCOC(=O)C1=NN(C2C1c3cccc4cccc2c34)c5ccc(C)cc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K18 compound treatment 12560.0 -29800.0 -1.73 15200.0 -30400.0 -2.3 -2.8456 -0.9901 3063390 Maybridge4_001998 Clc1ccccc1/C=C\2/N=C(N(CC=C)C2=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K19 compound treatment 22320.0 -20000.0 -1.16 22240.0 -23300.0 -1.76 -2.0689 -0.9794 3179696 Maybridge4_001999 O=C(NCC1COc2ccccc2O1)Nc3csc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K20 compound treatment 31440.0 -10900.0 -0.63 32520.0 -13000.0 -0.99 -1.1451 -0.977 3179697 Maybridge4_002000 CNC(=O)NC(=O)CSc1ncnc2sc(cc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K21 compound treatment 24320.0 -18000.0 -1.05 22360.0 -23200.0 -1.76 -1.9806 -0.9693 3063391 Maybridge4_002001 Cc1cc(C)c2c(N)c(sc2n1)c3nnc(SCc4ccc(Cl)cc4)n3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K22 compound treatment 29880.0 -12500.0 -0.72 32920.0 -12600.0 -0.96 -1.1876 -0.9905 3179698 Maybridge4_002002 S=c1[nH]nc(CSc2nc(cn2c3ccccc3)c4ccccc4)n1c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K23 mock treatment 40920.0 -1440.0 -0.08 37840.0 -7710.0 -0.58 -0.472 -0.8003 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 K24 mock treatment 28880.0 -13500.0 -0.78 36400.0 -9150.0 -0.69 -1.0423 -0.9982 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L01 compound treatment 31280.0 -11100.0 -0.64 32800.0 -12800.0 -0.97 -1.1366 -0.9804 3063422 Maybridge4_002003 CCOC(=O)CSc1nc(SCC(=O)OCC)c2c3CCCc3sc2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L02 compound treatment 39120.0 -3240.0 -0.19 44920.0 -633.0 -0.05 -0.1667 -0.8598 1536081 Maybridge4_002004 OC(=O)c1ccccc1Sc2ccccc2S(=O)(=O)NC3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L03 compound treatment 23920.0 -18400.0 -1.07 31000.0 -14600.0 -1.1 -1.5345 -0.9999 3179699 Maybridge4_002005 C=CCn1c(nc(c1c2ccccc2)c3ccccc3)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L04 compound treatment 33560.0 -8800.0 -0.51 44480.0 -1070.0 -0.08 -0.4181 -0.8095 1430538 Maybridge4_002006 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c2cccc(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L05 compound treatment 26760.0 -15600.0 -0.9 30600.0 -15000.0 -1.13 -1.4396 -0.9938 3179700 Maybridge4_002007 N=c1n(Nc2ccccc2)cnc3sc4CCCc4c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L06 compound treatment 31120.0 -11200.0 -0.65 40480.0 -5070.0 -0.38 -0.7321 -0.9682 3063426 Maybridge4_002008 Cc1ccc(cc1)C(=O)NC(NCc2ccco2)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L07 compound treatment 37320.0 -5040.0 -0.29 40280.0 -5270.0 -0.4 -0.4888 -0.9883 3179701 Maybridge4_002009 Brc1ccc(s1)c2ccc(Br)s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L08 compound treatment 26320.0 -16000.0 -0.93 28000.0 -17600.0 -1.33 -1.5968 -0.9847 1371799 Maybridge4_002010 CCOC(=O)C(C)Oc1ccc2c(cc(=O)oc2c1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L09 compound treatment 38120.0 -4240.0 -0.25 41480.0 -4070.0 -0.31 -0.3918 -0.9937 1134767 Maybridge4_002011 C1C(=Cc2ccccc12)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L10 compound treatment 36520.0 -5840.0 -0.34 34240.0 -11300.0 -0.86 -0.8449 -0.9176 1364288 Maybridge4_002012 O=C(NC1CCN(CC1)C(=O)C2CCC2)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L11 compound treatment 31320.0 -11000.0 -0.64 33400.0 -12200.0 -0.92 -1.1029 -0.9843 1570440 Maybridge4_002013 Oc1cc(Cc2ccccc2)cnc1CN3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L12 compound treatment 27720.0 -14600.0 -0.85 29960.0 -15600.0 -1.18 -1.4345 -0.9869 1227426 Maybridge4_002014 CC(C)C1CCC(C)CC1N(Cc2ccccc2)C(=O)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L13 compound treatment 29720.0 -12600.0 -0.73 28720.0 -16800.0 -1.27 -1.4189 -0.9655 1583701 Maybridge4_002015 N[C@@H](CO)CSCc1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L14 compound treatment 17760.0 -24600.0 -1.43 16760.0 -28800.0 -2.18 -2.5491 -0.9788 1368346 Maybridge4_002016 COc1cc(CCc2cc(OC)c(C)cc2OC)c(OC)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L15 compound treatment 34400.0 -7960.0 -0.46 39680.0 -5870.0 -0.44 -0.6406 -0.9998 3063428 Maybridge4_002017 FC(F)(F)C(NC(=O)c1ccccc1)(Nc2ccccc2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L16 compound treatment 4080.0 -38300.0 -2.22 3720.0 -41800.0 -3.17 -3.8075 -0.9848 1023708 Maybridge4_002018 COc1ccc(cc1)c2nc3ccccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L17 compound treatment 33120.0 -9240.0 -0.54 35320.0 -10200.0 -0.77 -0.9264 -0.9838 1344186 Maybridge4_002019 CC(=O)N1C(C(=O)NC1=S)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L18 compound treatment 33160.0 -9200.0 -0.53 33200.0 -12400.0 -0.94 -1.0382 -0.9645 3179703 Maybridge4_002020 CC(C)C(C)(Nc1ccccc1)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L19 compound treatment 31160.0 -11200.0 -0.65 35840.0 -9710.0 -0.74 -0.9788 -0.9981 1047316 Maybridge4_002021 OC(=O)c1ccc(s1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L20 compound treatment 13200.0 -29200.0 -1.69 13040.0 -32500.0 -2.46 -2.935 -0.9832 3179704 Maybridge4_002022 Brc1ccccc1C(=O)c2ccc-3c(c2)C(=O)c4ccccc43 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L21 compound treatment 22240.0 -20100.0 -1.17 24680.0 -20900.0 -1.58 -1.9416 -0.9888 3063451 Maybridge4_002023 FC(F)(F)C(NC(=O)c1ccccc1)(OCc2ccccc2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L22 compound treatment 38200.0 -4160.0 -0.24 45000.0 -553.0 -0.04 -0.2002 -0.8175 3179705 Maybridge4_002024 CCOC(=O)CSc1nncc(=O)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L23 mock treatment 38560.0 -3800.0 -0.22 41440.0 -4110.0 -0.31 -0.3759 -0.9857 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 L24 mock treatment 41560.0 -804.0 -0.05 44320.0 -1230.0 -0.09 -0.0989 -0.9485 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M01 compound treatment 45680.0 3320.0 0.19 51000.0 5450.0 0.41 0.4274 0.9396 3063453 Maybridge4_002025 Cc1ccc(CNC(=O)Nc2ccccc2)n1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M02 compound treatment 26840.0 -15500.0 -0.9 27960.0 -17600.0 -1.33 -1.5776 -0.9817 3179706 Maybridge4_002026 CCOC(=O)c1nnn2c1nc(SCc3ccc(F)cc3)c4ccccc42 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M03 compound treatment 9240.0 -33100.0 -1.92 14760.0 -30800.0 -2.33 -3.0052 -0.9953 3179707 Maybridge4_002027 O=C(Nc1ccc(OCc2ccccc2)cc1)OCC3CN(Cc4ccccc4)CCO3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M04 compound treatment 30840.0 -11500.0 -0.67 36240.0 -9310.0 -0.7 -0.9705 -0.9996 3063456 Maybridge4_002028 O=C(CC(C(=O)N1CCc2ccccc12)C(=O)N3CCc4ccccc34)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M05 compound treatment 40080.0 -2280.0 -0.13 42680.0 -2870.0 -0.22 -0.2473 -0.9716 3179708 Maybridge4_002029 O=C(OCC1CC(=NO1)c2ccccc2)c3cccc(n3)C(=O)OCC4CC(=NO4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M06 compound treatment 35720.0 -6640.0 -0.38 41600.0 -3950.0 -0.3 -0.4837 -0.9922 3063457 Maybridge4_002030 CC1=Nn2c(Cn3nnc4ccccc34)nnc2SC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M07 compound treatment 22880.0 -19500.0 -1.13 30960.0 -14600.0 -1.1 -1.5793 -0.9999 3179709 Maybridge4_002031 C/C(=N\O)/C(C)(C)Nc1ccc(cc1)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M08 compound treatment 17920.0 -24400.0 -1.42 19360.0 -26200.0 -1.98 -2.4033 -0.9864 3063458 Maybridge4_002032 O=C(Oc1cc(=O)oc2c3cccc4CCn(c(=O)c12)c43)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M09 compound treatment 35600.0 -6760.0 -0.39 36040.0 -9510.0 -0.72 -0.7862 -0.9591 2096080 Maybridge4_002033 CCOC(=O)c1sc2n(c3ccccc3)c(=S)n(c4ccccc4)c(=O)c2c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M10 compound treatment 24960.0 -17400.0 -1.01 29080.0 -16500.0 -1.25 -1.5947 -0.9945 3179710 Maybridge4_002034 CCOC(=O)N1CCc2c(C#N)c(NC(=O)CN3CCc4ccccc34)sc2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M11 compound treatment 26720.0 -15600.0 -0.91 23080.0 -22500.0 -1.7 -1.8437 -0.9566 3063459 Maybridge4_002035 O=C(COc1nc(cc(c2cccs2)c1C#N)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M12 compound treatment 30040.0 -12300.0 -0.71 32120.0 -13400.0 -1.02 -1.2238 -0.985 3063460 Maybridge4_002036 O=c1n(CN2CCOCC2)nc3sc4ccccc4n3c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M13 compound treatment 32840.0 -9520.0 -0.55 36320.0 -9230.0 -0.7 -0.8843 -0.9932 3179711 Maybridge4_002037 Nc1c(oc2nc(cc(c3cccs3)c12)c4ccco4)C(=O)c5ccc(Cl)cc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M14 compound treatment 28880.0 -13500.0 -0.78 32320.0 -13200.0 -1.0 -1.2607 -0.9924 3063486 Maybridge4_002038 Cc1nc2n(ncc2c(=O)n1NC(=O)Nc3ccc(Cl)c(Cl)c3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M15 compound treatment 31480.0 -10900.0 -0.63 28320.0 -17200.0 -1.3 -1.3682 -0.9444 3179712 Maybridge4_002039 CCOC(=O)c1nnn2c1n(CC=C)c(=O)c3ccccc32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M16 compound treatment 15960.0 -26400.0 -1.53 22400.0 -23200.0 -1.75 -2.3209 -0.9977 3063487 Maybridge4_002040 COC(=O)C1=C(C)N=C2SC(=C(N)N2C1c3cccs3)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M17 compound treatment 30080.0 -12300.0 -0.71 28160.0 -17400.0 -1.32 -1.4342 -0.9583 3179713 Maybridge4_002041 O=C/1NN=C(\C1=C\2/OC(=CS2)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M18 compound treatment 28240.0 -14100.0 -0.82 28800.0 -16800.0 -1.27 -1.4753 -0.9775 3179714 Maybridge4_002042 Clc1ccc(CN2C(=O)/C(=C\c3cccs3)/N=C2c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M19 compound treatment 31560.0 -10800.0 -0.63 34680.0 -10900.0 -0.82 -1.0245 -0.9909 3063489 Maybridge4_002043 COc1ccc(cc1)n2ncc(NC(=O)N3CCOCC3)c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M20 compound treatment 30440.0 -11900.0 -0.69 29280.0 -16300.0 -1.23 -1.3595 -0.9626 3179715 Maybridge4_002044 O=c1c(nc(nn1CN2CCOCC2)c3ccccc3)C(CN4CCOCC4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M21 compound treatment 22800.0 -19600.0 -1.13 22160.0 -23400.0 -1.77 -2.0536 -0.9768 3063490 Maybridge4_002045 Clc1ccccc1C2C3CCc4ccccc4C3=NN2C(=O)c5cccs5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M22 compound treatment 32640.0 -9720.0 -0.56 37880.0 -7670.0 -0.58 -0.809 -0.9999 3179716 Maybridge4_002046 CCOC(=O)c1cnc(nc1N)N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M23 mock treatment 37040.0 -5320.0 -0.31 40920.0 -4630.0 -0.35 -0.4661 -0.998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 M24 mock treatment 43560.0 1200.0 0.07 41720.0 -3830.0 -0.29 -0.1561 -0.5234 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N01 compound treatment 59840.0 17500.0 1.01 70280.0 24700.0 1.87 2.0395 0.9584 3063492 Maybridge4_002047 O=C1CSc2nnc(c3ccccc3)n12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N02 compound treatment 37640.0 -4720.0 -0.27 37480.0 -8070.0 -0.61 -0.6256 -0.9344 1229835 Maybridge4_002048 OC(=O)c1ccccc1Sc2ccccc2S(=O)(=O)NC3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N03 compound treatment 26600.0 -15800.0 -0.91 31120.0 -14400.0 -1.09 -1.4183 -0.996 1256899 Maybridge4_002049 c1csc(c1)c2nc(c([nH]2)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N04 compound treatment 28120.0 -14200.0 -0.83 36480.0 -9070.0 -0.69 -1.0691 -0.9958 3178130 Maybridge4_002050 CCCc1cc(O)nc(SC/C=C/c2ccccc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N05 compound treatment 10080.0 -32300.0 -1.87 15320.0 -30200.0 -2.29 -2.9408 -0.995 3178131 Maybridge4_002051 CCNc1nc(SCC(=O)NC(=O)NCc2ccccc2)nc3sc4CN(C)CCc4c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N06 compound treatment 20880.0 -21500.0 -1.24 28400.0 -17200.0 -1.3 -1.7982 -0.9998 3063494 Maybridge4_002052 CC1CN=C(S1)N(C2CCCCC2)C(=O)Nc3cccc(Cl)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N07 compound treatment 5000.0 -37400.0 -2.16 7560.0 -38000.0 -2.88 -3.5642 -0.9902 3178132 Maybridge4_002053 Cc1ccc(OC(=O)OCSc2nnn[nH]2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N08 compound treatment 37080.0 -5280.0 -0.31 35520.0 -10000.0 -0.76 -0.7534 -0.9202 1423044 Maybridge4_002054 CC(Oc1ccc2c(cc(=O)oc2c1)c3ccccc3)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N09 compound treatment 33440.0 -8920.0 -0.52 33480.0 -12100.0 -0.91 -1.0118 -0.9636 1177114 Maybridge4_002055 Brc1ccc(cc1)N2C(=O)C3=C(C2=O)C(=NCCN3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N10 compound treatment 26960.0 -15400.0 -0.89 33080.0 -12500.0 -0.94 -1.2986 -0.9996 1659522 Maybridge4_002056 Clc1cccc(Cl)c1C(=O)N2CCC(CC2)NC(=O)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N11 compound treatment 32680.0 -9680.0 -0.56 32480.0 -13100.0 -0.99 -1.0964 -0.9639 1381385 Maybridge4_002057 CN1C(=O)N(c2ccc(Cl)cc2)C(C)(O)CC1(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N12 compound treatment 30960.0 -11400.0 -0.66 31000.0 -14600.0 -1.1 -1.2461 -0.9701 1409714 Maybridge4_002058 COc1cccc(NC(=O)c2ccc(OC)c(OC)c2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N13 compound treatment 28720.0 -13600.0 -0.79 31720.0 -13800.0 -1.05 -1.2993 -0.9904 1704266 Maybridge4_002059 CC(C)(C)C(=O)Nc1ccccc1Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N14 compound treatment 34360.0 -8000.0 -0.46 36560.0 -8990.0 -0.68 -0.8092 -0.9825 3178133 Maybridge4_002060 NNC(=O)c1cc(S)ncn1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N15 compound treatment 28360.0 -14000.0 -0.81 36040.0 -9510.0 -0.72 -1.0829 -0.9982 3063524 Maybridge4_002061 CC(=O)NC(Nc1ccccc1)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N16 compound treatment 19000.0 -23400.0 -1.35 24120.0 -21400.0 -1.62 -2.1043 -0.9959 3178134 Maybridge4_002062 C/C(=N\c1ccccc1C(F)(F)F)/c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N17 compound treatment 30840.0 -11500.0 -0.67 34560.0 -11000.0 -0.83 -1.0605 -0.994 1020871 Maybridge4_002063 O=C1NC(C(=O)N1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N18 compound treatment 28360.0 -14000.0 -0.81 31880.0 -13700.0 -1.03 -1.3055 -0.9927 1667495 Maybridge4_002064 Clc1ccc2[nH]c(=O)c3nc(oc3c2c1)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N19 compound treatment 30840.0 -11500.0 -0.67 35560.0 -9990.0 -0.76 -1.0069 -0.9981 1670169 Maybridge4_002065 CC(C)c1ccc(cc1)S(=O)(=O)CC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N20 compound treatment 32720.0 -9640.0 -0.56 39520.0 -6030.0 -0.46 -0.718 -0.995 1596128 Maybridge4_002066 CCOC(=O)C1CCN(C1=O)S(=O)(=O)Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N21 compound treatment 21320.0 -21000.0 -1.22 23240.0 -22300.0 -1.69 -2.0564 -0.9872 1008385 Maybridge4_002067 O=C(c1ccccc1)c2ccccc2C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N22 compound treatment 34560.0 -7800.0 -0.45 35600.0 -9950.0 -0.75 -0.8524 -0.9702 1546853 Maybridge4_002068 Cn1c(=O)n(C)c2ncn(CC(O)CN(CC=C)CC=C)c2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N23 mock treatment 36480.0 -5880.0 -0.34 42480.0 -3070.0 -0.23 -0.4055 -0.9826 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 N24 mock treatment 38920.0 -3440.0 -0.2 45720.0 168.0 0.01 -0.1321 -0.6608 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O01 compound treatment 24760.0 -17600.0 -1.02 27880.0 -17700.0 -1.34 -1.6671 -0.991 3063527 Maybridge4_002069 O=C(Nc1sccc1c2nc3ccccc3s2)Nc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O02 compound treatment 44720.0 2360.0 0.14 48680.0 3130.0 0.24 0.2639 0.9658 3178135 Maybridge4_002070 CCOC(=O)CSc1nnc(Cn2nnc3ccccc23)n1c4ccc(F)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O03 compound treatment 44360.0 2000.0 0.12 52320.0 6770.0 0.51 0.444 0.8455 3063528 Maybridge4_002071 Cc1ccc(cc1)S(=O)(=O)NC(=O)OCC2CN(Cc3ccccc3)CCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O04 compound treatment 22240.0 -20100.0 -1.17 26520.0 -19000.0 -1.44 -1.8431 -0.9945 3178136 Maybridge4_002072 Cn1nc2c3ccccc3n(CC=C)c2nc1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O05 compound treatment 29120.0 -13200.0 -0.77 37920.0 -7630.0 -0.58 -0.9511 -0.9902 3178137 Maybridge4_002073 Clc1ccc(cc1)n2ncc(n2)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O06 compound treatment 37560.0 -4800.0 -0.28 40720.0 -4830.0 -0.37 -0.4555 -0.9909 3178138 Maybridge4_002074 Brc1ccc(cc1)C2=Nn3c(Cn4nnc5ccccc45)nnc3SC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O07 compound treatment 16240.0 -26100.0 -1.51 22480.0 -23100.0 -1.75 -2.3052 -0.9975 1760428 Maybridge4_002075 O=C(Nc1ccc2OCCOc2c1)c3ccc4nccnc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O08 compound treatment 41280.0 -1080.0 -0.06 42280.0 -3270.0 -0.25 -0.2196 -0.8592 3178139 Maybridge4_002076 CNC(=O)NC(=O)CSc1nnc(o1)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O09 compound treatment 37320.0 -5040.0 -0.29 39680.0 -5870.0 -0.44 -0.521 -0.9793 3178140 Maybridge4_002077 CCOC(=O)COc1c(C#N)sc2n(c3ccccc3)c(=S)n(c4ccccc4)c(=O)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O10 compound treatment 39360.0 -3000.0 -0.17 43360.0 -2190.0 -0.17 -0.2404 -0.9997 3063548 Maybridge4_002078 S=c1[nH]c(=S)c2cnc(nc2[nH]1)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O11 compound treatment 38800.0 -3560.0 -0.21 38080.0 -7470.0 -0.57 -0.546 -0.9067 1200067 Maybridge4_002079 Cc1cc(C)c2c(N)c(sc2n1)C(=O)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O12 compound treatment 36600.0 -5760.0 -0.33 39400.0 -6150.0 -0.47 -0.5654 -0.9867 2102976 Maybridge4_002080 COc1ccc(cc1)C2=Nn3c(SC2)nc4sc5CCCCc5c4c3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O13 compound treatment 360.0 -42000.0 -2.43 400.0 -45200.0 -3.42 -4.1376 -0.9861 3063550 Maybridge4_002081 Cc1cc(C)c(C#N)c(Sc2ncnc3n(Cc4ccccc4)nnc23)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O14 compound treatment 22480.0 -19900.0 -1.15 33160.0 -12400.0 -0.94 -1.4779 -0.9948 3178141 Maybridge4_002082 O=c1n(/N=C/c2cccs2)cnc3sc(cc13)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O15 compound treatment 26000.0 -16400.0 -0.95 24720.0 -20800.0 -1.58 -1.7854 -0.9704 3178142 Maybridge4_002083 CCOC(=O)c1nnn2c1n(Cc3ccc(Cl)cc3)c(=O)c4ccccc42 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O16 compound treatment 26000.0 -16400.0 -0.95 30760.0 -14800.0 -1.12 -1.4621 -0.9966 3063551 Maybridge4_002084 COc1cc(/C=N/n2c(C)nc3n(cnc3c2=O)c4ccccc4)cc(OC)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O17 compound treatment 35240.0 -7120.0 -0.41 38840.0 -6710.0 -0.51 -0.6511 -0.9947 3178143 Maybridge4_002085 O=c1nc2n(nc(c3ccccc3)n2c(c1C#N)c4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O18 compound treatment 28800.0 -13600.0 -0.79 29960.0 -15600.0 -1.18 -1.3903 -0.9805 3063552 Maybridge4_002086 C1Cc2ccccc2N1c3ncnc4sc(cc34)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O19 compound treatment 33880.0 -8480.0 -0.49 36920.0 -8630.0 -0.65 -0.8096 -0.9901 3178144 Maybridge4_002087 COc1ccc(cc1)n2ncc(NC(=O)Nc3ccc4OCCCOc4c3)c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O20 compound treatment 37040.0 -5320.0 -0.31 45720.0 168.0 0.01 -0.2091 -0.6775 3063553 Maybridge4_002088 Nc1ncnc2nc(ncc12)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O21 compound treatment 21760.0 -20600.0 -1.19 28960.0 -16600.0 -1.26 -1.7322 -0.9997 3178145 Maybridge4_002089 CC(=O)N1N=C2C(CCc3ccccc23)C1c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O22 compound treatment 38880.0 -3480.0 -0.2 51880.0 6330.0 0.48 0.196 0.377 3063554 Maybridge4_002090 Cc1cc(=O)n2ncnc2n1CC(=O)NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O23 mock treatment 40240.0 -2120.0 -0.12 47440.0 1890.0 0.14 0.014 0.0744 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 O24 mock treatment 44920.0 2560.0 0.15 48640.0 3090.0 0.23 0.27 0.9758 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P01 compound treatment 51000.0 8640.0 0.5 54200.0 8650.0 0.65 0.8167 0.9912 1504248 Maybridge4_002091 C1Cc2ccccc2N1c3ncnc4n(ncc34)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P02 compound treatment 8800.0 -33600.0 -1.94 12320.0 -33200.0 -2.52 -3.1538 -0.9919 1485949 Maybridge4_002092 CC(CN1CCN(Cc2ccccc2)CC1)N(C(=O)c3ccc(cc3)C(C)(C)C)c4ccccn4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P03 compound treatment 31920.0 -10400.0 -0.61 37600.0 -7950.0 -0.6 -0.8535 -1.0 3063615 Maybridge4_002093 O=C/1NNC(=N\C1=C/c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P04 compound treatment 35600.0 -6760.0 -0.39 41120.0 -4430.0 -0.34 -0.5143 -0.997 3178146 Maybridge4_002094 Cn1cnnc1Sc2cc(C#N)c(C#N)cc2Sc3nncn3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P05 compound treatment 16800.0 -25600.0 -1.48 27280.0 -18300.0 -1.38 -2.0253 -0.9994 3063618 Maybridge4_002095 CCNc1nc(SCc2ccc(Cl)cc2)nc3sc4CN(C)CCc4c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P06 compound treatment 32160.0 -10200.0 -0.59 43040.0 -2510.0 -0.19 -0.5525 -0.8897 3178147 Maybridge4_002096 Cn1cnc(c1C#N)n2oo2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P07 compound treatment 32240.0 -10100.0 -0.59 36840.0 -8710.0 -0.66 -0.8811 -0.9983 1405262 Maybridge4_002097 O=C(NCc1ccccc1)NC2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P08 compound treatment 14480.0 -27900.0 -1.62 16560.0 -29000.0 -2.19 -2.6941 -0.9886 1585718 Maybridge4_002098 CCOC(=O)C(C)Oc1cc(O)c2c(=O)cc(oc2c1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P09 compound treatment 38360.0 -4000.0 -0.23 36320.0 -9230.0 -0.7 -0.6582 -0.8939 3178148 Maybridge4_002099 COC(=O)/C(=C/C(=O)c1c(F)c(F)c(OC)c(F)c1F)/O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P10 compound treatment 33920.0 -8440.0 -0.49 35680.0 -9870.0 -0.75 -0.8743 -0.9789 1497616 Maybridge4_002100 O=C(Cc1ccccc1)NC2CCN(CC2)C(=O)C3CCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P11 compound treatment 36680.0 -5680.0 -0.33 36560.0 -8990.0 -0.68 -0.7142 -0.9445 3178149 Maybridge4_002101 O=c1ccc2CCCCc2n1CCC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P12 compound treatment 35360.0 -7000.0 -0.41 36840.0 -8710.0 -0.66 -0.7533 -0.9728 1054556 Maybridge4_002102 Cc1ccc(NS(=O)(=O)c2ccccc2)c(NS(=O)(=O)c3ccccc3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P13 compound treatment 32440.0 -9920.0 -0.57 33120.0 -12400.0 -0.94 -1.072 -0.9721 1043550 Maybridge4_002103 OC1CCN(Cc2ccccc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P14 compound treatment 35680.0 -6680.0 -0.39 35040.0 -10500.0 -0.8 -0.8365 -0.9452 1240290 Maybridge4_002104 CC(C)(C)OC(=O)N1CCN(Cc2ccccc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P15 compound treatment 26720.0 -15600.0 -0.91 34960.0 -10600.0 -0.8 -1.2078 -0.9981 3063648 Maybridge4_002105 CC(=O)NC(NCc1ccccc1)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P16 compound treatment 22440.0 -19900.0 -1.15 28000.0 -17600.0 -1.33 -1.7557 -0.9975 3178234 Maybridge4_002106 CC(C)[C@H]1COC(=N1)c2cccc(n2)C3=N[C@H](CO3)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P17 compound treatment 37720.0 -4640.0 -0.27 37040.0 -8510.0 -0.64 -0.6459 -0.925 3063650 Maybridge4_002107 CC(O)/C=C/c1cccc[n+]1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P18 compound treatment 24760.0 -17600.0 -1.02 27840.0 -17700.0 -1.34 -1.6692 -0.9909 3178235 Maybridge4_002108 CCOC(=O)C1=C(C)N(C(=O)Oc2ccccc2)C(=NC1c3ccccc3)SC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P19 compound treatment 30760.0 -11600.0 -0.67 38640.0 -6910.0 -0.52 -0.8454 -0.9923 3063651 Maybridge4_002109 CN1C(=O)/C(=C\Nc2ccc(Cl)cc2)/C(=O)c3c1n(C)c(=O)n(C)c3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P20 compound treatment 24400.0 -18000.0 -1.04 27920.0 -17600.0 -1.33 -1.6797 -0.9924 1466385 Maybridge4_002110 COC(=O)C1=C(C)NC(=C(C1C)C(=O)OC)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P21 compound treatment 8920.0 -33400.0 -1.94 8240.0 -37300.0 -2.82 -3.3672 -0.9831 1646281 Maybridge4_002111 COc1cccc(c1)c2ncc(o2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P22 compound treatment 41000.0 -1360.0 -0.08 43440.0 -2110.0 -0.16 -0.1689 -0.9472 1592521 Maybridge4_002112 O=C(Nc1ccccc1)N(Cc2ccccc2)c3cccc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P23 mock treatment 34520.0 -7840.0 -0.45 44120.0 -1430.0 -0.11 -0.398 -0.8519 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2054 P24 mock treatment 40160.0 -2200.0 -0.13 39360.0 -6190.0 -0.47 -0.4217 -0.8681 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A01 compound treatment 61480.0 10900.0 0.63 58120.0 15900.0 1.2 1.2989 0.9546 3178236 Maybridge4_002113 CCOC(=O)c1c(C)n[nH]c1/N=C/c2ccc(OC)c(OC)c2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A02 compound treatment 37560.0 -13000.0 -0.75 34760.0 -7440.0 -0.56 -0.9314 -0.9897 3178237 Maybridge4_002114 CS/C(=C(/C#N)\S(=O)(=O)c1ccc(Cl)cc1)/NC2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A03 compound treatment 48640.0 -1930.0 -0.11 52720.0 10500.0 0.8 0.4838 0.6018 1739670 Maybridge4_002115 O=C(C(C(=O)N1CCCCC1)C2(CC3CC4CC(C3)C2)C4)N5CCCCC5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A04 compound treatment 34680.0 -15900.0 -0.92 22040.0 -20200.0 -1.53 -1.7302 -0.9707 3178238 Maybridge4_002116 CSc1c(C#N)c(nn1C)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A05 compound treatment 56000.0 5430.0 0.31 46680.0 4480.0 0.34 0.4621 0.9993 3063681 Maybridge4_002117 CN(C)c1nc(O)nc(n1)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A06 compound treatment 39280.0 -11300.0 -0.65 37160.0 -5040.0 -0.38 -0.7325 -0.9671 3178239 Maybridge4_002118 CN1c2ccccc2C(=O)/C(=C\Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F)/S1(=O)=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A07 compound treatment 40640.0 -9930.0 -0.58 30520.0 -11700.0 -0.88 -1.0321 -0.9784 1532269 Maybridge4_002119 COc1cc2CCN=C(c3ccccc3NC(=O)c4cccc(Cl)c4)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A08 compound treatment 52880.0 2310.0 0.13 51120.0 8920.0 0.68 0.5719 0.831 1424615 Maybridge4_002120 CCCS(=O)(=O)C1=C(N)OC(=C(C#N)C1c2ccc(Cl)cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A09 compound treatment 36160.0 -14400.0 -0.84 26840.0 -15400.0 -1.16 -1.4127 -0.9868 1227957 Maybridge4_002121 Cc1cc(N(S(=O)(=O)c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)n(C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A10 compound treatment 22320.0 -28300.0 -1.64 19520.0 -22700.0 -1.72 -2.3714 -0.9997 3063685 Maybridge4_002122 CS/C(=C(/C#N)\C(=O)c1ccc(Cl)cc1)/NCC2CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A11 compound treatment 38640.0 -11900.0 -0.69 31760.0 -10400.0 -0.79 -1.0477 -0.9978 1505422 Maybridge4_002123 O=C(Nc1cc(nn1c2ccccc2)C3CC3)Nc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A12 compound treatment 60000.0 9430.0 0.55 44320.0 2120.0 0.16 0.4996 0.8777 3063686 Maybridge4_002124 CC(C)S(=O)(=O)/C(=C/Nc1ncccn1)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A13 compound treatment 45080.0 -5490.0 -0.32 34480.0 -7720.0 -0.58 -0.6383 -0.9592 1730851 Maybridge4_002125 Cc1ccc(cc1)C2C(=C(N)OC(=C2C#N)C3CC3)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A14 compound treatment 51520.0 948.0 0.05 43840.0 1640.0 0.12 0.1265 0.9328 3063688 Maybridge4_002126 Cn1ccnc1S(=O)(=O)/C(=C/c2ccc3OCOc3c2)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A15 compound treatment 45960.0 -4610.0 -0.27 39280.0 -2920.0 -0.22 -0.3453 -0.9956 1337308 Maybridge4_002127 CCOC(=O)c1cnc2n(C)nc(C3CC3)c2c1N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A16 compound treatment 48440.0 -2130.0 -0.12 41600.0 -601.0 -0.05 -0.1195 -0.9079 3063690 Maybridge4_002128 Cc1cc(nc2c(Br)c(nn12)C(C)(C)C)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A17 compound treatment 52360.0 1790.0 0.1 45360.0 3160.0 0.24 0.2423 0.9299 1574781 Maybridge4_002129 COc1c(Cl)scc1NC(=O)N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A18 compound treatment 720.0 -49900.0 -2.89 600.0 -41600.0 -3.15 -4.269 -0.9991 3063692 Maybridge4_002130 CSC(=C(C#N)C(=O)c1cccc(c1)C(F)(F)F)SC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A19 compound treatment 47600.0 -2970.0 -0.17 40240.0 -1960.0 -0.15 -0.2268 -0.9973 3178240 Maybridge4_002131 Clc1ccccc1C(=O)C(=C2SCCCS2)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A20 compound treatment 53200.0 2630.0 0.15 47000.0 4800.0 0.36 0.3645 0.9255 1150123 Maybridge4_002132 CC(C)CC(NC(=O)Cc1ccsc1)C(=O)NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A21 compound treatment 57480.0 6910.0 0.4 40440.0 -1760.0 -0.13 0.1887 0.4474 3063728 Maybridge4_002133 COc1cccc(c1)c2nc(N)nc(SC)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A22 compound treatment 49880.0 -693.0 -0.04 42120.0 -81.3 -0.01 -0.0327 -0.8061 3178241 Maybridge4_002134 Fc1ccc(N/C=C(\C#N)/S(=O)(=O)Cc2ccco2)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A23 mock treatment 61040.0 10500.0 0.61 14320.0 -27900.0 -2.11 -1.0635 -0.4843 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 A24 mock treatment 68160.0 17600.0 1.02 52600.0 10400.0 0.79 1.2771 0.9919 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B01 compound treatment 60280.0 9710.0 0.56 55800.0 13600.0 1.03 1.1256 0.9596 3178242 Maybridge4_002135 FC(F)(F)c1cc(CN/C=C(\C#N)/S(=O)(=O)Cc2ccco2)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B02 compound treatment 57600.0 7030.0 0.41 53200.0 11000.0 0.83 0.8766 0.9459 3063731 Maybridge4_002136 COC(=O)c1ccc2C(=O)/C(=C/Nc3ccc(Cl)cc3)/S(=O)(=O)N(C)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B03 compound treatment 35400.0 -15200.0 -0.88 31480.0 -10700.0 -0.81 -1.1954 -0.9992 3178243 Maybridge4_002137 CSc1sc(/C(=N\O)/C)c2CC(C)(C)C/C(=N/O)/c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B04 compound treatment 55160.0 4590.0 0.27 44840.0 2640.0 0.2 0.3292 0.9901 3063732 Maybridge4_002138 COC(=O)c1sc(SC)c(c1C)c2ccon2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B05 compound treatment 35040.0 -15500.0 -0.9 32440.0 -9760.0 -0.74 -1.1588 -0.9952 3178244 Maybridge4_002139 Clc1ccc(Sc2ccccc2CN/C(=C(\N=C\c3cccs3)/C#N)/C#N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B06 compound treatment 29360.0 -21200.0 -1.23 26320.0 -15900.0 -1.2 -1.7191 -0.9999 3063733 Maybridge4_002140 CN(C)/C=C/C(=O)c1ccc2OC(C)(C)CCc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B07 compound treatment 41920.0 -8650.0 -0.5 36320.0 -5880.0 -0.45 -0.6693 -0.9982 1330787 Maybridge4_002141 Clc1ccc(cc1)C(=O)N(CCS(=O)(=O)c2ccc(Cl)cc2)Cc3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B08 compound treatment 54360.0 3790.0 0.22 46520.0 4320.0 0.33 0.3863 0.9812 3063734 Maybridge4_002142 Clc1ccc(cc1)S(=O)(=O)C(=C2SCCCCS2)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B09 compound treatment 40240.0 -10300.0 -0.6 30800.0 -11400.0 -0.86 -1.0335 -0.984 1191188 Maybridge4_002143 CSc1scc2CCc3cn(nc3-c12)C(=O)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B10 compound treatment 19600.0 -31000.0 -1.79 14080.0 -28100.0 -2.13 -2.774 -0.9964 1483249 Maybridge4_002144 CC1(C)CCc2cc(ccc2O1)c3ccn(n3)S(=O)(=O)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B11 compound treatment 27000.0 -23600.0 -1.37 19880.0 -22300.0 -1.69 -2.1604 -0.9944 3178245 Maybridge4_002145 Cc1csc2sc(C(=O)c3ccc(Cl)cc3)c(C)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B12 compound treatment 45440.0 -5130.0 -0.3 40160.0 -2040.0 -0.15 -0.3195 -0.9535 3063735 Maybridge4_002146 FC(F)(F)c1cc(n2ncc(C(=O)NC(=S)Nc3ccccc3Cl)c2n1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B13 compound treatment 48880.0 -1690.0 -0.1 39160.0 -3040.0 -0.23 -0.2321 -0.9277 1629969 Maybridge4_002147 CCOC(=O)c1sc(SC)c-2c1CCc3cnc(SC)nc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B14 compound treatment 17080.0 -33500.0 -1.94 10720.0 -31500.0 -2.38 -3.0571 -0.9948 3178246 Maybridge4_002148 CC(C)CSc1nnc(CSCc2nc(cs2)c3ccc(Cl)cc3)n1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B15 compound treatment 45680.0 -4890.0 -0.28 39680.0 -2520.0 -0.19 -0.3354 -0.9815 1122221 Maybridge4_002149 Clc1ccc(cc1)C2CC(=CC(=S)S2)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B16 compound treatment 45440.0 -5130.0 -0.3 38040.0 -4160.0 -0.31 -0.433 -0.9996 3063769 Maybridge4_002150 NNC(=O)c1ccc(CSc2ccc(cn2)C(F)(F)F)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B17 compound treatment 46000.0 -4570.0 -0.26 41200.0 -1000.0 -0.08 -0.2409 -0.8743 3178247 Maybridge4_002151 COC(=O)C1=C(CSC1)Nc2ccc(OC(=O)Nc3ccc(OC(F)(F)F)cc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B18 compound treatment 37160.0 -13400.0 -0.78 31320.0 -10900.0 -0.82 -1.1319 -0.9996 3063773 Maybridge4_002152 CC(C)(C)SC(=O)c1cccnc1SCCS(=O)(=O)c2cccc(c2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B19 compound treatment 40640.0 -9930.0 -0.58 32320.0 -9880.0 -0.75 -0.9358 -0.9916 3178248 Maybridge4_002153 Cc1csc2sc(/C=N/Cc3cccs3)c(C)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B20 compound treatment 720.0 -49900.0 -2.89 720.0 -41500.0 -3.14 -4.2626 -0.9991 1206852 Maybridge4_002154 CCOC(=O)c1cnc2n(C)nc(C)c2c1Sc3nnc(SC)s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B21 compound treatment 58400.0 7830.0 0.45 45080.0 2880.0 0.22 0.4748 0.9436 3178249 Maybridge4_002155 CS(=O)(=O)c1sc(C(=O)NC(=S)Nc2ccc(OC(F)(F)F)cc2)c3CCC=Cc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B22 compound treatment 13280.0 -37300.0 -2.16 10080.0 -32100.0 -2.43 -3.2471 -0.9983 3178341 Maybridge4_002156 CCOC(=O)CC1Sc2ccccc2N=C1SCC(=O)Nc3cccc(c3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B23 mock treatment 61520.0 10900.0 0.63 49360.0 7160.0 0.54 0.8317 0.9969 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 B24 mock treatment 61000.0 10400.0 0.6 56800.0 14600.0 1.11 1.2086 0.9596 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C01 compound treatment 16440.0 -34100.0 -1.98 15000.0 -27200.0 -2.06 -2.8543 -0.9998 3063777 Maybridge4_002157 CCN(CC)C(=S)NC(=S)c1ccc(C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C02 compound treatment 51040.0 468.0 0.03 47280.0 5080.0 0.38 0.291 0.7551 3178342 Maybridge4_002158 COC(=O)c1ccccc1S(=O)(=O)/C(=C/Nc2nc(C)cc(C)n2)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C03 compound treatment 48760.0 -1810.0 -0.11 43160.0 959.0 0.07 -0.0229 -0.1797 1199477 Maybridge4_002159 CN(C1CCS(=O)(=O)C1)C(=O)COc2ccc(Oc3ccccc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C04 compound treatment 27680.0 -22900.0 -1.33 21600.0 -20600.0 -1.56 -2.0405 -0.9968 3178343 Maybridge4_002160 CSc1c(C#N)c(nn1C(=O)C(C)(C)C)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C05 compound treatment 40600.0 -9970.0 -0.58 32160.0 -10000.0 -0.76 -0.946 -0.9908 3063778 Maybridge4_002161 CS/C(=N/C(=N)Nc1ccc(Cl)cc1)/N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C06 compound treatment 15400.0 -35200.0 -2.04 11280.0 -30900.0 -2.34 -3.096 -0.9976 3178344 Maybridge4_002162 Cc1c(csc1C(=O)Nc2ccc(F)cc2F)S(=O)(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C07 compound treatment 37600.0 -13000.0 -0.75 29960.0 -12200.0 -0.93 -1.1867 -0.9946 1368486 Maybridge4_002163 OC(=O)c1ccccc1SCC(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C08 compound treatment 49040.0 -1530.0 -0.09 45000.0 2800.0 0.21 0.087 0.3788 3178345 Maybridge4_002164 CNC(=S)Nc1cscc1S(=O)(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C09 compound treatment 54600.0 4030.0 0.23 50560.0 8360.0 0.63 0.6124 0.9081 3063810 Maybridge4_002165 Clc1cccc(NC(=S)NC(C#N)c2ccccc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C10 compound treatment 48760.0 -1810.0 -0.11 41720.0 -481.0 -0.04 -0.1 -0.8998 3178346 Maybridge4_002166 CN(C)/C=C/C(=O)c1cnc2cc(C)nn2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C11 compound treatment 52920.0 2350.0 0.14 45560.0 3360.0 0.25 0.2759 0.957 1175106 Maybridge4_002167 Cc1c(nnc2cc(nn12)c3ccccc3)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C12 compound treatment 51000.0 428.0 0.02 42160.0 -41.3 0.0 0.0153 0.613 3178347 Maybridge4_002168 COC(=O)c1scc(c1n2cccc2)S(=O)(=O)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C13 compound treatment 30680.0 -19900.0 -1.15 24720.0 -17500.0 -1.32 -1.7506 -0.9976 1474680 Maybridge4_002169 NC1=C(C#N)C(C(=C(O1)C2CC2)C#N)c3ccccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C14 compound treatment 27640.0 -22900.0 -1.33 26840.0 -15400.0 -1.16 -1.7617 -0.9978 1123050 Maybridge4_002170 CC(C)S(=O)(=O)c1cscc1NC(=O)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C15 compound treatment 52120.0 1550.0 0.09 43520.0 1320.0 0.1 0.134 0.9986 1443948 Maybridge4_002171 O=c1c2CSCc2[nH]c3cc(nn13)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C16 compound treatment 1280.0 -49300.0 -2.86 1040.0 -41200.0 -3.12 -4.2225 -0.9991 3063812 Maybridge4_002172 CC(C)S(=O)(=O)c1csc(NC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C17 compound treatment 51520.0 948.0 0.05 41560.0 -641.0 -0.05 0.0045 0.0613 1153510 Maybridge4_002173 COc1c(Cl)scc1NC(=O)N2CC(C)OC(C)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C18 compound treatment 48920.0 -1650.0 -0.1 39480.0 -2720.0 -0.21 -0.2134 -0.9393 3063813 Maybridge4_002174 CS(=O)(=O)c1scc(c1C#N)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C19 compound treatment 46640.0 -3930.0 -0.23 45720.0 3520.0 0.27 0.0272 0.0777 3178348 Maybridge4_002175 CC(C)(C)c1ccc(cc1)c2n[nH]c(c2C#N)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C20 compound treatment 19200.0 -31400.0 -1.82 21040.0 -21200.0 -1.6 -2.4179 -0.998 3178349 Maybridge4_002176 Cn1nc(cc1C(F)(F)F)c2ccc(s2)C(=O)Nc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C21 compound treatment 52720.0 2150.0 0.12 44200.0 2000.0 0.15 0.195 0.9953 3063814 Maybridge4_002177 COC(=O)c1sc(SC)c(C#N)c1c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C22 compound treatment 47600.0 -2970.0 -0.17 37960.0 -4240.0 -0.32 -0.3488 -0.9574 3178350 Maybridge4_002178 CCN(CCS(=O)(=O)c1ccc(C)cc1)C(=O)c2ccc(s2)c3cc(nn3C)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C23 mock treatment 57120.0 6550.0 0.38 49880.0 7680.0 0.58 0.6792 0.9786 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 C24 mock treatment 55720.0 5150.0 0.3 52120.0 9920.0 0.75 0.7418 0.9182 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D01 compound treatment 57800.0 7230.0 0.42 46240.0 4040.0 0.31 0.5123 0.988 3063815 Maybridge4_002179 Nc1nc(ncc1S(=O)(=O)Cc2ccco2)c3ccncc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D02 compound treatment 57720.0 7150.0 0.41 41080.0 -1120.0 -0.08 0.2328 0.5507 3063818 Maybridge4_002180 CC(C)(C)S(=O)(=O)c1cnc(nc1N)c2cnccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D03 compound treatment 41560.0 -9010.0 -0.52 37800.0 -4400.0 -0.33 -0.6048 -0.9764 3178351 Maybridge4_002181 Cc1csc2sc(COC(=O)Nc3ccccc3)c(C)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D04 compound treatment 45480.0 -5090.0 -0.3 38560.0 -3640.0 -0.28 -0.4035 -0.9994 3178352 Maybridge4_002182 CSc1sc(C(=O)NN)c2CCCC3(SCCS3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D05 compound treatment 38120.0 -12500.0 -0.72 28640.0 -13600.0 -1.03 -1.236 -0.9851 3063851 Maybridge4_002183 CCOC(=O)c1sc(c2/C(=N\O)/CC(C)(C)Cc12)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D06 compound treatment 28000.0 -22600.0 -1.31 28840.0 -13400.0 -1.01 -1.6399 -0.9919 3178353 Maybridge4_002184 Cc1ccc(cc1)S(=O)(=O)CCSc2sc(C#N)c3CC(C)(C)CC(=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D07 compound treatment 49200.0 -1370.0 -0.08 38640.0 -3560.0 -0.27 -0.2468 -0.8783 1145089 Maybridge4_002185 CSc1sc(C(=O)O)c-2c1S(=O)(=O)N(C)c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D08 compound treatment 57160.0 6590.0 0.38 45960.0 3760.0 0.28 0.4711 0.9895 3178354 Maybridge4_002186 FC(F)(F)c1cccc(c1)C(=O)C(=C2SCCCCS2)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D09 compound treatment 33960.0 -16600.0 -0.96 26960.0 -15200.0 -1.15 -1.4964 -0.9959 3063853 Maybridge4_002187 Cn1nc(cc1C(F)(F)F)c2ccc(s2)S(=O)(=O)NCc3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D10 compound treatment 41080.0 -9490.0 -0.55 30160.0 -12000.0 -0.91 -1.0334 -0.9707 3178355 Maybridge4_002188 CC1(C)CCc2cc(ccc2O1)c3ccn(n3)S(=O)(=O)c4cccc(c4)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D11 compound treatment 42920.0 -7650.0 -0.44 36520.0 -5680.0 -0.43 -0.6176 -0.9999 3063854 Maybridge4_002189 CSc1sc(cc1S(=O)(=O)C(C)C)C(=O)Sc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D12 compound treatment 50400.0 -173.0 -0.01 38680.0 -3520.0 -0.27 -0.1955 -0.7331 3178356 Maybridge4_002190 CC1(C)CCc2cc(ccc2O1)c3ccnc(S)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D13 compound treatment 40600.0 -9970.0 -0.58 34200.0 -8000.0 -0.61 -0.8368 -0.9997 3063856 Maybridge4_002191 Cc1c(Br)sc2sc(c(C)c12)c3nn(C)cc3Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D14 compound treatment 38000.0 -12600.0 -0.73 26240.0 -16000.0 -1.21 -1.3694 -0.9707 3178357 Maybridge4_002192 CSc1sc(Cl)c2CC(C)(C)C/C(=N/O)/c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D15 compound treatment 16120.0 -34500.0 -2.0 13280.0 -28900.0 -2.19 -2.9594 -0.9989 3178358 Maybridge4_002193 CC(C)NC(=O)CSc1nccc(n1)c2sc3sc(Br)c(C)c3c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D16 compound treatment 50600.0 27.5 0.0 34520.0 -7680.0 -0.58 -0.41 -0.7052 3063857 Maybridge4_002194 Sc1nccc(n1)c2ccc3OCCc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D17 compound treatment 54160.0 3590.0 0.21 34680.0 -7520.0 -0.57 -0.2556 -0.4217 3063858 Maybridge4_002195 COc1ccc(CSc2nnc(CSc3cccs3)n2C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D18 compound treatment 46440.0 -4130.0 -0.24 43160.0 959.0 0.07 -0.118 -0.4716 3178359 Maybridge4_002196 CS(=O)(=NS(=O)(=O)c1cccc2nsnc12)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D19 compound treatment 43080.0 -7490.0 -0.43 36000.0 -6200.0 -0.47 -0.6389 -0.9992 3178360 Maybridge4_002197 Cc1cc2ncc(c(C)n2n1)c3ccnc(SCCS(=O)(=O)c4ccccc4)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D20 compound treatment 51400.0 828.0 0.05 45200.0 3000.0 0.23 0.1944 0.838 3063859 Maybridge4_002198 CC(C)C1Oc2c(cccc2N(CC(=O)O)C1=S)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D21 compound treatment 48280.0 -2290.0 -0.13 40600.0 -1600.0 -0.12 -0.1796 -0.999 3178361 Maybridge4_002199 CSc1nc(nc(c1C#N)c2ccc(OC(F)(F)F)cc2)c3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D22 compound treatment 11120.0 -39500.0 -2.29 10480.0 -31700.0 -2.4 -3.3141 -0.9997 1139728 Maybridge4_002200 CCOC(=O)CC1Sc2ccccc2N=C1SCCS(=O)(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D23 mock treatment 59400.0 8830.0 0.51 51560.0 9360.0 0.71 0.8626 0.9872 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 D24 mock treatment 54720.0 4150.0 0.24 47000.0 4800.0 0.36 0.4268 0.9799 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E01 compound treatment 48280.0 -2290.0 -0.13 44520.0 2320.0 0.18 0.0302 0.1371 1149948 Maybridge4_002201 Clc1ccc(cc1)N2CCN(CC2)C3=Cc4ccccc4C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E02 compound treatment 53600.0 3030.0 0.18 45680.0 3480.0 0.26 0.3102 0.9805 3178362 Maybridge4_002202 COC(=O)c1ccccc1S(=O)(=O)/C(=C/Nc2nc(SC)nc(n2)C3CC3)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E03 compound treatment 43480.0 -7090.0 -0.41 37160.0 -5040.0 -0.38 -0.5604 -0.9993 3063320 Maybridge4_002203 CSc1nc(N)n(n1)c2cc(Cl)cc(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E04 compound treatment 3360.0 -47200.0 -2.74 2760.0 -39400.0 -2.99 -4.0453 -0.999 3178363 Maybridge4_002204 CSc1n[nH]c(NC(=O)c2ccccc2Cl)c1S(=O)(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E05 compound treatment 49120.0 -1450.0 -0.08 42080.0 -121.0 -0.01 -0.066 -0.7796 1032087 Maybridge4_002205 Oc1ccnc(SCc2ccc(Cl)cc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E06 compound treatment 49080.0 -1490.0 -0.09 43760.0 1560.0 0.12 0.0223 0.1523 3178364 Maybridge4_002206 CN1c2ccccc2C(=O)/C(=C\Nc3ncccn3)/S1(=O)=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E07 compound treatment 53240.0 2670.0 0.15 42800.0 599.0 0.05 0.1413 0.8775 3063324 Maybridge4_002207 CCN(CCC#N)C(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E08 compound treatment 52360.0 1790.0 0.1 41080.0 -1120.0 -0.08 0.0132 0.0987 1520456 Maybridge4_002208 CCOC(=O)NS(=O)(=O)c1ccccc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E09 compound treatment 50640.0 67.5 0.0 42600.0 399.0 0.03 0.0241 0.7921 1248613 Maybridge4_002209 O=c1cc([nH]c2cc(nn12)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E10 compound treatment 58080.0 7510.0 0.43 44960.0 2760.0 0.21 0.4552 0.9435 3178365 Maybridge4_002210 Cc1cccc(c1)c2n[nH]c(c2C#N)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E11 compound treatment 36520.0 -14100.0 -0.81 31560.0 -10600.0 -0.81 -1.1453 -1.0 1374930 Maybridge4_002211 COc1cccc(c1)c2c(nnc3cc(nn23)c4ccccc4)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E12 compound treatment 34320.0 -16300.0 -0.94 30360.0 -11800.0 -0.9 -1.2996 -0.9997 1289071 Maybridge4_002212 Clc1ccc(cc1)S(=O)(=O)CCSc2ccccc2NC(=O)c3ccccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E13 compound treatment 41280.0 -9290.0 -0.54 36840.0 -5360.0 -0.41 -0.6677 -0.9903 1391332 Maybridge4_002213 COc1ccc(cc1)C2C(=C(N)OC(=C2C#N)C3CC3)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E14 compound treatment 47640.0 -2930.0 -0.17 37000.0 -5200.0 -0.39 -0.3985 -0.9294 3063326 Maybridge4_002214 Cc1nccc(n1)c2cccc(NS(=O)(=O)c3ccccc3C(F)(F)F)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E15 compound treatment 50840.0 268.0 0.02 42720.0 519.0 0.04 0.0387 0.9173 3178456 Maybridge4_002215 Cn1nc(cc1N)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E16 compound treatment 43760.0 -6810.0 -0.39 36680.0 -5520.0 -0.42 -0.5746 -0.9996 1540260 Maybridge4_002216 CC(C)S(=O)(=O)c1csc(NC(=O)N2CCCCC2)c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E17 compound treatment 33440.0 -17100.0 -0.99 25840.0 -16400.0 -1.24 -1.5776 -0.994 1698879 Maybridge4_002217 Nc1nc(ncc1S(=O)(=O)c2ccc(Cl)cc2)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E18 compound treatment 14360.0 -36200.0 -2.1 17680.0 -24500.0 -1.86 -2.796 -0.9981 1598720 Maybridge4_002218 Clc1ccc(cc1)c2csc(S(=O)C3CCCCC3)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E19 compound treatment 51880.0 1310.0 0.08 38640.0 -3560.0 -0.27 -0.137 -0.4894 1438402 Maybridge4_002219 O=C(c1ccccc1)c2cnc3ccccn3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E20 compound treatment 31920.0 -18700.0 -1.08 32320.0 -9880.0 -0.75 -1.293 -0.9838 3178457 Maybridge4_002220 CN(C)c1scc(c1C#N)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E21 compound treatment 14280.0 -36300.0 -2.1 12200.0 -30000.0 -2.27 -3.0926 -0.9993 3178458 Maybridge4_002221 Cc1ccc(cc1)S(=O)(=O)/C(=C/Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E22 compound treatment 47920.0 -2650.0 -0.15 37600.0 -4600.0 -0.35 -0.3549 -0.9324 1367919 Maybridge4_002222 O=S(=O)(Cc1ccco1)Cc2nc(cs2)c3ccc(cc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E23 mock treatment 55440.0 4870.0 0.28 44880.0 2680.0 0.2 0.3428 0.9869 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 E24 mock treatment 56200.0 5630.0 0.33 45400.0 3200.0 0.24 0.4018 0.9893 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F01 compound treatment 53040.0 2470.0 0.14 43560.0 1360.0 0.1 0.1738 0.9869 3063357 Maybridge4_002223 CNC(=O)c1cc(C#N)c(SC)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F02 compound treatment 47160.0 -3410.0 -0.2 40480.0 -1720.0 -0.13 -0.2319 -0.9795 3178459 Maybridge4_002224 CSc1scc2CCc3cnc(SCC(=O)c4ccc(Cl)cc4)nc3-c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F03 compound treatment 49240.0 -1330.0 -0.08 46640.0 4440.0 0.34 0.183 0.5308 3063358 Maybridge4_002225 Cc1csc2sc(C(=O)Oc3ccc(Cl)cc3)c(C)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F04 compound treatment 44040.0 -6530.0 -0.38 39520.0 -2680.0 -0.2 -0.4111 -0.9573 3178460 Maybridge4_002226 Nc1nc(ncc1S(=O)(=O)c2ccc(cn2)C(F)(F)F)N3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F05 compound treatment 51520.0 948.0 0.05 46000.0 3800.0 0.29 0.2421 0.8272 3063359 Maybridge4_002227 CSc1sc(cc1c2nc(C)cs2)C(=O)NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F06 compound treatment 3320.0 -47300.0 -2.74 2920.0 -39300.0 -2.97 -4.0383 -0.9991 3178461 Maybridge4_002228 CC(C)S(=O)(=O)c1cscc1NC(=O)c2ccc(s2)c3cc(nn3C)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F07 compound treatment 47720.0 -2850.0 -0.17 40160.0 -2040.0 -0.15 -0.2261 -0.9994 1693988 Maybridge4_002229 CS(=O)(=O)c1sc(C(=O)Nc2ccccc2Cl)c3CCC=Cc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F08 compound treatment 43640.0 -6930.0 -0.4 34600.0 -7600.0 -0.58 -0.6909 -0.9846 3178462 Maybridge4_002230 CSc1sc(c2ccon2)c(c1C#N)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F09 compound treatment 22800.0 -27800.0 -1.61 17120.0 -25100.0 -1.9 -2.4802 -0.9966 3178463 Maybridge4_002231 CC1(C)CC(=O)C=C(SCC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)S1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F10 compound treatment 48160.0 -2410.0 -0.14 39640.0 -2560.0 -0.19 -0.2359 -0.9871 3063360 Maybridge4_002232 FC(F)(F)c1ccc(nc1)S(=O)(=O)Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F11 compound treatment 46320.0 -4250.0 -0.25 35080.0 -7120.0 -0.54 -0.5554 -0.9371 3178464 Maybridge4_002233 CS(=O)(=NS(=O)(=O)c1ccc(s1)c2ccccn2)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F12 compound treatment 24160.0 -26400.0 -1.53 23840.0 -18400.0 -1.39 -2.0648 -0.9988 3063362 Maybridge4_002234 C/S(=N\C(=O)Nc1ccc(Cl)cc1)/c2sc(Cl)c3CCCC(=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F13 compound treatment 49120.0 -1450.0 -0.08 40400.0 -1800.0 -0.14 -0.1559 -0.9731 3178465 Maybridge4_002235 CS(=O)(=NC(=S)NC(=O)Oc1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F14 compound treatment 46760.0 -3810.0 -0.22 34200.0 -8000.0 -0.61 -0.5845 -0.9066 3063392 Maybridge4_002236 FC(F)(F)c1cnc(N2CCS(=NC(=O)c3ccccc3)CC2)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F15 compound treatment 13160.0 -37400.0 -2.17 11800.0 -30400.0 -2.3 -3.1599 -0.9996 3178466 Maybridge4_002237 Cc1c(Br)sc2sc(c(C)c12)c3ccnc(SCC(=O)NCC=C)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F16 compound treatment 29280.0 -21300.0 -1.23 20000.0 -22200.0 -1.68 -2.0606 -0.9884 1201268 Maybridge4_002238 C(Sc1nccc(n1)c2ccc3OCCc3c2)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F17 compound treatment 42000.0 -8570.0 -0.5 27280.0 -14900.0 -1.13 -1.1498 -0.9319 1378146 Maybridge4_002239 CS(=O)(=O)c1sc(NC(=O)Nc2ccc(Cl)cc2)c3CCC=Cc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F18 compound treatment 35360.0 -15200.0 -0.88 27520.0 -14700.0 -1.11 -1.409 -0.9934 1406686 Maybridge4_002240 Cc1nn(Cc2cccc(c2)C(=O)NC(=O)Nc3ccc(Cl)cc3)c(C)c1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F19 compound treatment 44320.0 -6250.0 -0.36 38000.0 -4200.0 -0.32 -0.481 -0.9979 1721379 Maybridge4_002241 O=S(=O)(N1CCCCC1)c2ccc(s2)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F20 compound treatment 50840.0 268.0 0.02 43520.0 1320.0 0.1 0.0815 0.8072 3063394 Maybridge4_002242 CN(C)/C=C\1/C(=O)c2sccc2N(C)S1(=O)=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F21 compound treatment 51320.0 748.0 0.04 41720.0 -481.0 -0.04 0.0049 0.0859 3178467 Maybridge4_002243 CSc1sc(c(C)c1c2ccnc(S)n2)c3nc(C)cs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F22 compound treatment 44520.0 -6050.0 -0.35 41040.0 -1160.0 -0.09 -0.3101 -0.8578 1422989 Maybridge4_002244 Clc1ccc(OC(=O)c2csc(n2)C3COc4ccccc4O3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F23 mock treatment 56880.0 6310.0 0.37 47680.0 5480.0 0.41 0.5516 0.998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 F24 mock treatment 56400.0 5830.0 0.34 44840.0 2640.0 0.2 0.38 0.9686 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G01 compound treatment 34760.0 -15800.0 -0.92 36920.0 -5280.0 -0.4 -0.9305 -0.9309 1651892 Maybridge4_002245 CCCCC1(Cc2ccccc2)C(=O)Nc3ccccc3C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G02 compound treatment 47240.0 -3330.0 -0.19 43640.0 1440.0 0.11 -0.0595 -0.2685 3178468 Maybridge4_002246 CSc1nc(N/C=C(\C#N)/S(=O)(=O)c2ccccc2Cl)nc(n1)C3CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G03 compound treatment 50960.0 388.0 0.02 36760.0 -5440.0 -0.41 -0.2754 -0.6676 3063398 Maybridge4_002247 CC(=N)NC(=S)Nc1ccc(Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G04 compound treatment 35040.0 -15500.0 -0.9 25880.0 -16300.0 -1.24 -1.5099 -0.9879 3178469 Maybridge4_002248 CSc1n[nH]c(NC(=O)Nc2ccccc2)c1S(=O)(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G05 compound treatment 40840.0 -9730.0 -0.56 36040.0 -6160.0 -0.47 -0.7285 -0.9956 3063400 Maybridge4_002249 CN(C)C(=O)Oc1ccnc(SCc2c(F)cccc2Cl)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G06 compound treatment 13360.0 -37200.0 -2.16 15120.0 -27100.0 -2.05 -2.974 -0.9997 3178470 Maybridge4_002250 COc1ccc(cc1)c2n[nH]c(SC)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G07 compound treatment 51320.0 748.0 0.04 41360.0 -841.0 -0.06 -0.0144 -0.1871 3063401 Maybridge4_002251 Cc1ccc(COc2ccc(I)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G08 compound treatment 23440.0 -27100.0 -1.57 18640.0 -23600.0 -1.78 -2.3727 -0.998 3178471 Maybridge4_002252 CSc1sc(C(=O)Nc2cccc(Cl)c2)c(c1C#N)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G09 compound treatment 36160.0 -14400.0 -0.84 31320.0 -10900.0 -0.82 -1.1729 -1.0 1687124 Maybridge4_002253 CCN(CCS(=O)(=O)c1ccccc1)S(=O)(=O)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G10 compound treatment 47000.0 -3570.0 -0.21 35480.0 -6720.0 -0.51 -0.5061 -0.9214 3178472 Maybridge4_002254 COC(=O)c1scc(c1N)S(=O)(=O)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G11 compound treatment 52120.0 1550.0 0.09 43120.0 919.0 0.07 0.1126 0.9921 1226475 Maybridge4_002255 NC(=O)c1nnc2cc(nn2c1N)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G12 compound treatment 9920.0 -40700.0 -2.36 8560.0 -33600.0 -2.55 -3.4661 -0.9992 1452741 Maybridge4_002256 Clc1ccc(cc1)S(=O)(=O)CCSc2ccccc2NC(=O)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G13 compound treatment 4560.0 -46000.0 -2.67 3320.0 -38900.0 -2.94 -3.9661 -0.9988 3063431 Maybridge4_002257 Fc1cccc(Cl)c1CN/C(=C(\N=C\c2cccs2)/C#N)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G14 compound treatment 37040.0 -13500.0 -0.78 19680.0 -22500.0 -1.7 -1.7598 -0.9379 3178473 Maybridge4_002258 Clc1cccc(Cl)c1CSc2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G15 compound treatment 43360.0 -7210.0 -0.42 35280.0 -6920.0 -0.52 -0.6659 -0.9937 3178474 Maybridge4_002259 COc1ccc(/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G16 compound treatment 28920.0 -21700.0 -1.25 19760.0 -22400.0 -1.7 -2.0882 -0.9889 1133071 Maybridge4_002260 CNC(=O)Nc1ccccc1NC2=C(CSC2)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G17 compound treatment 35640.0 -14900.0 -0.87 28280.0 -13900.0 -1.05 -1.3569 -0.9952 3178475 Maybridge4_002261 CC1CN(CC(C)O1)/C=C(\C#N)/S(=O)(=O)c2ccc(Br)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G18 compound treatment 40960.0 -9610.0 -0.56 32840.0 -9360.0 -0.71 -0.8949 -0.9929 3063432 Maybridge4_002262 CS(=O)(=NS(=O)(=O)c1ccccc1C(F)(F)F)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G19 compound treatment 41320.0 -9250.0 -0.54 38560.0 -3640.0 -0.28 -0.574 -0.9522 1259331 Maybridge4_002263 COCc1cc(O)nc2n(C)nc(c3cccs3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G20 compound treatment 45400.0 -5170.0 -0.3 38560.0 -3640.0 -0.28 -0.4068 -0.9991 3063433 Maybridge4_002264 CS/C(=C(/C#N)\S(=O)(=O)C(C)C)/N1CCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G21 compound treatment 49680.0 -893.0 -0.05 39280.0 -2920.0 -0.22 -0.1929 -0.8495 3178476 Maybridge4_002265 CSc1c(C#N)c(nn1CC(=O)NN)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G22 compound treatment 33240.0 -17300.0 -1.0 30240.0 -12000.0 -0.91 -1.3503 -0.9987 3063434 Maybridge4_002266 Cc1onc(c1C(=O)N=S(=O)(C)C)c2c(Cl)cccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G23 mock treatment 48520.0 -2050.0 -0.12 40760.0 -1440.0 -0.11 -0.1612 -0.9991 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 G24 mock treatment 52800.0 2230.0 0.13 43480.0 1280.0 0.1 0.1597 0.9899 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H01 compound treatment 47600.0 -2970.0 -0.17 39160.0 -3040.0 -0.23 -0.2846 -0.9898 3178477 Maybridge4_002267 CCOC(=O)c1sc(SCc2ccccc2)c(c1n3cccc3)S(=O)(=O)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H02 compound treatment 25600.0 -25000.0 -1.45 19320.0 -22900.0 -1.73 -2.2478 -0.996 1259984 Maybridge4_002268 CSc1scc2CCc3cnc(SCC(=O)C(C)(C)C)nc3-c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H03 compound treatment 52360.0 1790.0 0.1 40360.0 -1840.0 -0.14 -0.0253 -0.1458 3063436 Maybridge4_002269 CSc1sc(cc1S(=O)(=O)C(C)C)C(=O)NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H04 compound treatment 37960.0 -12600.0 -0.73 34200.0 -8000.0 -0.61 -0.945 -0.9956 3178558 Maybridge4_002270 COC(=O)c1sc(SCCOC(=O)c2ccccc2Cl)c3C(=O)CC(C)(C)Cc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H05 compound treatment 45880.0 -4690.0 -0.27 39360.0 -2840.0 -0.22 -0.3443 -0.9933 3063438 Maybridge4_002271 CSc1sc(C#N)c(C)c1c2ccn(n2)C(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H06 compound treatment 30840.0 -19700.0 -1.14 26400.0 -15800.0 -1.2 -1.6542 -0.9997 3178559 Maybridge4_002272 CSc1sc(C(=O)/C=C/N(C)C)c(c1C#N)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H07 compound treatment 120.0 -50500.0 -2.92 80.0 -42100.0 -3.19 -4.3214 -0.9991 1222048 Maybridge4_002273 CS(=O)c1sc(C(=O)OCc2ccccc2)c3CC(C)(C)CC(=O)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H08 compound treatment 37240.0 -13300.0 -0.77 25120.0 -17100.0 -1.29 -1.4605 -0.9697 3178560 Maybridge4_002274 CSc1sc(c2cc[nH]n2)c(c1C#N)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H09 compound treatment 42720.0 -7850.0 -0.45 28320.0 -13900.0 -1.05 -1.0647 -0.9299 3178561 Maybridge4_002275 CC1(C)CC(=O)C=C(SCc2c(Cl)cccc2Cl)S1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H10 compound treatment 35080.0 -15500.0 -0.9 32640.0 -9560.0 -0.72 -1.1465 -0.9943 1307156 Maybridge4_002276 CC1(C)CCc2cc(ccc2O1)c3ccn(n3)C(=O)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H11 compound treatment 38120.0 -12500.0 -0.72 31320.0 -10900.0 -0.82 -1.0926 -0.9978 3063440 Maybridge4_002277 CSc1nnc(c2ccc(s2)S(=O)(=O)n3nc(C)cc3C)n1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H12 compound treatment 19560.0 -31000.0 -1.8 17520.0 -24700.0 -1.87 -2.5916 -0.9998 3178562 Maybridge4_002278 CCSc1nccc(n1)c2ccc3OC(C)(C)CCc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H13 compound treatment 42440.0 -8130.0 -0.47 28320.0 -13900.0 -1.05 -1.0762 -0.9345 3063442 Maybridge4_002279 Cc1csc2sc(c(C)c12)c3ccnc(SCc4ccccc4)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H14 compound treatment 29880.0 -20700.0 -1.2 25720.0 -16500.0 -1.25 -1.7299 -0.9998 3178563 Maybridge4_002280 CCOC(=O)c1sc(/S(=N/C(=O)Nc2ccccc2Cl)/C)c3C=CCCc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H15 compound treatment 34280.0 -16300.0 -0.94 24600.0 -17600.0 -1.33 -1.6096 -0.9858 1505800 Maybridge4_002281 COC(=O)C(CC(C)C)NS(=O)(=O)c1ccc(s1)c2nnc(SC)n2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H16 compound treatment 46680.0 -3890.0 -0.23 34040.0 -8160.0 -0.62 -0.5963 -0.9067 3178564 Maybridge4_002282 FC(F)(F)c1ccc(nc1)S(=O)(=O)CCSc2ncccc2C(=O)NCc3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H17 compound treatment 29480.0 -21100.0 -1.22 26200.0 -16000.0 -1.21 -1.7206 -1.0 3178565 Maybridge4_002283 Clc1ccc(cc1)C2CC(=O)C=C(SCC(=O)c3ccccc3)S2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H18 compound treatment 42000.0 -8570.0 -0.5 35520.0 -6680.0 -0.51 -0.7088 -1.0 3063443 Maybridge4_002284 C/C(=N\O)/c1ccc2OCCc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H19 compound treatment 47280.0 -3290.0 -0.19 41600.0 -601.0 -0.05 -0.1671 -0.8519 3063445 Maybridge4_002285 CC1(C)CC(=O)c2c(SCC(=O)NN)sc(C#N)c2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H20 compound treatment 47600.0 -2970.0 -0.17 40280.0 -1920.0 -0.15 -0.2246 -0.9965 1254429 Maybridge4_002286 Cc1nn(C)c2ncc(C(=O)N)c(Oc3cccnc3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H21 compound treatment 17440.0 -33100.0 -1.92 14400.0 -27800.0 -2.1 -2.8454 -0.9989 3063446 Maybridge4_002287 CCOC(=O)c1sc(SC)c2c1CCCC32SCCS3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H22 compound treatment 41560.0 -9010.0 -0.52 41680.0 -521.0 -0.04 -0.3971 -0.7584 1921420 Maybridge4_002288 OC(=O)/C=C/1\OC(=O)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H23 mock treatment 49200.0 -1370.0 -0.08 42360.0 159.0 0.01 -0.0477 -0.5935 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 H24 mock treatment 45040.0 -5530.0 -0.32 32040.0 -10200.0 -0.77 -0.7705 -0.9247 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I01 compound treatment 40560.0 -10000.0 -0.58 36240.0 -5960.0 -0.45 -0.7293 -0.9923 3178566 Maybridge4_002289 Cc1ccc(cc1)C(=O)OC[C@H]2O[C@@H](C[C@@H]2OC(=O)c3ccc(C)cc3)c4nnc5ncccn45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I02 compound treatment 25040.0 -25500.0 -1.48 23680.0 -18500.0 -1.4 -2.0374 -0.9996 3178567 Maybridge4_002290 FC(F)(F)c1cc(N/C=C(\C#N)/S(=O)(=O)Cc2ccc(Cl)cc2)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I03 compound treatment 43080.0 -7490.0 -0.43 35920.0 -6280.0 -0.48 -0.6432 -0.999 3063447 Maybridge4_002291 CCOC(=O)c1c(C)noc1c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I04 compound treatment 38560.0 -12000.0 -0.7 33680.0 -8520.0 -0.65 -0.9482 -0.9993 3064096 Maybridge4_002292 CSc1sc(NC(=O)N2CCOCC2)c(c1C#N)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I05 compound treatment 44800.0 -5770.0 -0.33 42040.0 -161.0 -0.01 -0.2451 -0.7324 3064097 Maybridge4_002293 CCOC(=O)/C=C/1\NC(=O)CS1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I06 compound treatment 28520.0 -22100.0 -1.28 26560.0 -15600.0 -1.18 -1.7406 -0.9993 3064098 Maybridge4_002294 CSc1[nH]nc(c1C#N)c2cccc(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I07 compound treatment 44880.0 -5690.0 -0.33 39800.0 -2400.0 -0.18 -0.3617 -0.9606 3064099 Maybridge4_002295 Fc1ccc(NC(=S)N(CCC#N)CC2CCCO2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I08 compound treatment 47760.0 -2810.0 -0.16 38320.0 -3880.0 -0.29 -0.323 -0.9613 3064100 Maybridge4_002296 CSc1sc(C(=O)O)c(C)c1S(=O)(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I09 compound treatment 37880.0 -12700.0 -0.74 34480.0 -7720.0 -0.58 -0.9333 -0.9935 1242964 Maybridge4_002297 Cc1nn(c(NC(=O)c2ccccc2)c1C#N)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I10 compound treatment 39040.0 -11500.0 -0.67 34960.0 -7240.0 -0.55 -0.86 -0.9952 3064101 Maybridge4_002298 CC(C)(C)S(=O)(=O)/C(=C/Nc1ccccn1)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I11 compound treatment 41880.0 -8690.0 -0.5 37360.0 -4840.0 -0.37 -0.6152 -0.9878 1003716 Maybridge4_002299 Cc1ccc(cc1)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I12 compound treatment 41560.0 -9010.0 -0.52 33560.0 -8640.0 -0.65 -0.8317 -0.9938 3064102 Maybridge4_002300 COC(=O)c1scc(c1/N=C/N(C)C)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I13 compound treatment 34880.0 -15700.0 -0.91 27480.0 -14700.0 -1.11 -1.4308 -0.9949 3178568 Maybridge4_002301 COc1cccc(c1)C(=O)/C=c/2\[nH]c(=O)\c(=C/c3cccs3)\s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I14 compound treatment 35080.0 -15500.0 -0.9 25760.0 -16400.0 -1.24 -1.5147 -0.9871 1621333 Maybridge4_002302 Cc1nccc(n1)c2cccc(NC(=O)Nc3ccccc3)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I15 compound treatment 29800.0 -20800.0 -1.2 26040.0 -16200.0 -1.22 -1.716 -1.0 1156135 Maybridge4_002303 CC(C)(C)c1ccc(cc1)c2n[nH]c(NS(=O)(=O)c3ccccc3)c2Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I16 compound treatment 36560.0 -14000.0 -0.81 26400.0 -15800.0 -1.2 -1.4198 -0.9822 3064103 Maybridge4_002304 COC(=O)c1sc(SC)c(C#N)c1c2cccc(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I17 compound treatment 31160.0 -19400.0 -1.12 26160.0 -16000.0 -1.21 -1.6539 -0.9993 1665125 Maybridge4_002305 O=C(Nc1ccccc1)Nc2ccc(cc2)C3SCCS3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I18 compound treatment 40400.0 -10200.0 -0.59 27880.0 -14300.0 -1.08 -1.1833 -0.959 3064104 Maybridge4_002306 O=S(=O)(C(=C1SCCCS1)C#N)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I19 compound treatment 29840.0 -20700.0 -1.2 23280.0 -18900.0 -1.43 -1.8621 -0.9962 3178569 Maybridge4_002307 CSc1nc2cc(C)nn2c(c1C#N)c3ccc(cc3)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I20 compound treatment 45240.0 -5330.0 -0.31 39960.0 -2240.0 -0.17 -0.3384 -0.9602 3178570 Maybridge4_002308 Cc1ccc(cc1)S(=O)(=NC(=O)NC(=O)c2c(Cl)cccc2Cl)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I21 compound treatment 48120.0 -2450.0 -0.14 37800.0 -4400.0 -0.33 -0.336 -0.9278 3064105 Maybridge4_002309 CSc1nc(C)nc(N/C=C(\C#N)/S(=O)(=O)c2ccc(C)cc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I22 compound treatment 47280.0 -3290.0 -0.19 38040.0 -4160.0 -0.31 -0.3576 -0.9711 1118314 Maybridge4_002310 NNC(=O)c1csc(CS(=O)(=O)Cc2ccco2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I23 mock treatment 49720.0 -853.0 -0.05 38240.0 -3960.0 -0.3 -0.2469 -0.8126 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 I24 mock treatment 51800.0 1230.0 0.07 41000.0 -1200.0 -0.09 -0.014 -0.1214 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J01 compound treatment 28520.0 -22100.0 -1.28 24760.0 -17400.0 -1.32 -1.837 -0.9999 3064106 Maybridge4_002311 CSc1sc(c2n[nH]cc2Br)c3CC(C)(C)CC(=O)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J02 compound treatment 44200.0 -6370.0 -0.37 33080.0 -9120.0 -0.69 -0.7493 -0.957 3178571 Maybridge4_002312 CSc1scc2CCc3cnc(SCC(=O)NCC=C)nc3-c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J03 compound treatment 45720.0 -4850.0 -0.28 31400.0 -10800.0 -0.82 -0.7769 -0.8986 3064107 Maybridge4_002313 CSc1sc(C#N)c2CC(CC(=O)c12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J04 compound treatment 46560.0 -4010.0 -0.23 36120.0 -6080.0 -0.46 -0.4899 -0.9499 3178572 Maybridge4_002314 NC(=S)c1cnn2c(cc(nc12)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J05 compound treatment 37960.0 -12600.0 -0.73 36920.0 -5280.0 -0.4 -0.7994 -0.9597 3064108 Maybridge4_002315 COC(=O)c1sccc1N/C=C(\C#N)/S(=O)(=O)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J06 compound treatment 41960.0 -8610.0 -0.5 34160.0 -8040.0 -0.61 -0.7832 -0.9951 3178573 Maybridge4_002316 CCOC(=O)c1sc(SC)c-2c1CCc3conc32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J07 compound treatment 41240.0 -9330.0 -0.54 31400.0 -10800.0 -0.82 -0.9605 -0.9798 3178574 Maybridge4_002317 Cc1nn(Cc2nnc(o2)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)c(C)c1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J08 compound treatment 27800.0 -22800.0 -1.32 23800.0 -18400.0 -1.39 -1.9179 -0.9996 3064109 Maybridge4_002318 CCCS(=O)(=O)/C(=C/c1sccc1Oc2ccccc2)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J09 compound treatment 31720.0 -18900.0 -1.09 26920.0 -15300.0 -1.16 -1.5903 -0.9996 3178575 Maybridge4_002319 Cc1ccc(cc1)S(=O)(=O)CCSC2=CC(=O)CC(C)(C)S2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J10 compound treatment 35480.0 -15100.0 -0.87 29160.0 -13000.0 -0.99 -1.3163 -0.9982 3064110 Maybridge4_002320 Clc1ccc(cc1)c2ccnc(SCCS(=O)(=O)c3ccc(Cl)cc3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J11 compound treatment 17280.0 -33300.0 -1.93 18400.0 -23800.0 -1.8 -2.6379 -0.9994 3178576 Maybridge4_002321 CSc1sc(C(=O)Sc2ccccc2)c-3c1S(=O)(=O)N(C)c4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J12 compound treatment 31040.0 -19500.0 -1.13 23200.0 -19000.0 -1.44 -1.8172 -0.993 1454764 Maybridge4_002322 CCOC(=O)C1=C(Nc2ccc(OC(=O)C)cc2)C(=O)N(C1)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J13 compound treatment 37880.0 -12700.0 -0.74 30840.0 -11400.0 -0.86 -1.1281 -0.997 3178577 Maybridge4_002323 Cc1csc2sc(c(C)c12)c3ccnc(SCC(=O)c4ccccc4)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J14 compound treatment 30600.0 -20000.0 -1.16 25280.0 -16900.0 -1.28 -1.7239 -0.9987 3178578 Maybridge4_002324 CCOC(=O)c1sc(/S(=N/S(=O)(=O)c2cccc(Cl)c2)/C)c3C=CCCc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J15 compound treatment 37880.0 -12700.0 -0.74 32520.0 -9680.0 -0.73 -1.0382 -1.0 3064111 Maybridge4_002325 COc1cccc(NC(=S)N=S(=O)(C)c2ccccc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J16 compound treatment 44440.0 -6130.0 -0.36 36400.0 -5800.0 -0.44 -0.5617 -0.9945 3178579 Maybridge4_002326 CCCCc1ccc(NC(=O)N=S2CCN(CC2)c3ncc(cc3Cl)C(F)(F)F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J17 compound treatment 35800.0 -14800.0 -0.86 25480.0 -16700.0 -1.27 -1.5002 -0.9818 3064112 Maybridge4_002327 Cc1nn(Cc2nnc(SCc3c(Cl)cccc3Cl)o2)c(C)c1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J18 compound treatment 49320.0 -1250.0 -0.07 36920.0 -5280.0 -0.4 -0.334 -0.822 3178580 Maybridge4_002328 C/S(=N/C(=O)Nc1ccc(Cl)cc1)/c2ccc(OC(=O)c3ccc(Cl)cc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J19 compound treatment 30040.0 -20500.0 -1.19 22920.0 -19300.0 -1.46 -1.8732 -0.9949 3064113 Maybridge4_002329 CS(=O)(=NS(=O)(=O)c1cc(cs1)S(=O)(=O)c2ccccc2)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J20 compound treatment 30480.0 -20100.0 -1.16 24840.0 -17400.0 -1.31 -1.7524 -0.9982 1183286 Maybridge4_002330 CN1c2ccsc2-c3nc(SCc4ccc(Cl)cc4)ncc3S1(=O)=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J21 compound treatment 48880.0 -1690.0 -0.1 37640.0 -4560.0 -0.35 -0.3135 -0.8734 3064114 Maybridge4_002331 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)CCSc2ccc(cn2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J22 compound treatment 42080.0 -8490.0 -0.49 39240.0 -2960.0 -0.22 -0.5064 -0.9366 3178581 Maybridge4_002332 O=C(CCN1CCC(=N1)c2cccs2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J23 mock treatment 49960.0 -613.0 -0.04 37360.0 -4840.0 -0.37 -0.2842 -0.772 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 J24 mock treatment 48960.0 -1610.0 -0.09 41400.0 -801.0 -0.06 -0.1089 -0.9781 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K01 compound treatment 49800.0 -773.0 -0.04 32800.0 -9400.0 -0.71 -0.5348 -0.7501 3064115 Maybridge4_002333 C/C(=C\C#N)/Nc1c(C)n(C)n(c2ccccc2)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K02 compound treatment 41560.0 -9010.0 -0.52 31280.0 -10900.0 -0.83 -0.9538 -0.9755 3178657 Maybridge4_002334 CSc1sc(C(=O)O)c(c1C#N)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K03 compound treatment 39000.0 -11600.0 -0.67 37640.0 -4560.0 -0.35 -0.7182 -0.9524 1629094 Maybridge4_002335 NC(=S)NN1C2CSC1CS2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K04 compound treatment 37760.0 -12800.0 -0.74 32280.0 -9920.0 -0.75 -1.0559 -1.0 3178658 Maybridge4_002336 CSc1c(C#N)c(nn1C(=O)c2cccs2)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K05 compound treatment 35680.0 -14900.0 -0.86 29240.0 -13000.0 -0.98 -1.3039 -0.9979 3178659 Maybridge4_002337 FC(F)(F)c1cccc(c1)S(=O)(=O)N2CCCN3C2c4ccccc4C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K06 compound treatment 35320.0 -15300.0 -0.88 29680.0 -12500.0 -0.95 -1.2951 -0.9994 3064116 Maybridge4_002338 CSc1nc(/N=C/N(C)C)n2nc(cc2n1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K07 compound treatment 39840.0 -10700.0 -0.62 33680.0 -8520.0 -0.65 -0.8958 -0.9998 3178660 Maybridge4_002339 CN(CCC#N)C(=S)Nc1ccc(F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K08 compound treatment 33920.0 -16700.0 -0.96 30760.0 -11400.0 -0.87 -1.2946 -0.9985 3064117 Maybridge4_002340 COC(=O)c1scc(C#N)c1/N=C/N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K09 compound treatment 27760.0 -22800.0 -1.32 22440.0 -19800.0 -1.5 -1.9923 -0.9981 1197958 Maybridge4_002341 CCN(CCS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K10 compound treatment 29960.0 -20600.0 -1.19 24360.0 -17800.0 -1.35 -1.7994 -0.9981 1372972 Maybridge4_002342 COc1ncccc1C(=O)Nc2ccc(F)cc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K11 compound treatment 34400.0 -16200.0 -0.94 26440.0 -15800.0 -1.19 -1.5062 -0.9929 3178661 Maybridge4_002343 CC(=O)Nc1c(Br)c(nn1c2ccccc2)C3CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K12 compound treatment 35880.0 -14700.0 -0.85 27360.0 -14800.0 -1.12 -1.3963 -0.9906 3064118 Maybridge4_002344 O=S(=O)(/C(=C/c1ccc(\C=C(/C#N)\S(=O)(=O)c2ccccc2)cc1)/C#N)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K13 compound treatment 36160.0 -14400.0 -0.84 30600.0 -11600.0 -0.88 -1.2114 -0.9997 3178662 Maybridge4_002345 Oc1c2CN(C3CCCCC3)C(=O)c2nc4cc(nn14)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K14 compound treatment 32480.0 -18100.0 -1.05 26960.0 -15200.0 -1.15 -1.557 -0.9989 1503351 Maybridge4_002346 CNC(=O)Nc1cccc(c1)c2ccnc(C)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K15 compound treatment 29640.0 -20900.0 -1.21 26800.0 -15400.0 -1.17 -1.6819 -0.9998 3178663 Maybridge4_002347 Clc1ccc(cc1)S(=O)(=O)/C(=C/c2ccccc2Cl)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K16 compound treatment 35960.0 -14600.0 -0.85 30800.0 -11400.0 -0.86 -1.2089 -1.0 1326810 Maybridge4_002348 CC(C)S(=O)(=O)c1cnc(nc1N)N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K17 compound treatment 33120.0 -17500.0 -1.01 27120.0 -15100.0 -1.14 -1.5222 -0.9982 3064119 Maybridge4_002349 CNC(=O)Nc1ccc(cc1)C2SCCS2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K18 compound treatment 6080.0 -44500.0 -2.58 4240.0 -38000.0 -2.87 -3.8546 -0.9985 1218060 Maybridge4_002350 CCOC(=O)c1cnc2c(csc2c1Sc3ccc(Cl)cc3)S(=O)(=O)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K19 compound treatment 34440.0 -16100.0 -0.93 26880.0 -15300.0 -1.16 -1.481 -0.9943 3064120 Maybridge4_002351 CSc1nc2cc(C)nn2c(c3ccco3)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K20 compound treatment 3360.0 -47200.0 -2.74 4360.0 -37800.0 -2.86 -3.9596 -0.9997 1209169 Maybridge4_002352 CS(=O)N(C(=O)c1scc(c1C)S(=O)(=O)c2ccc(Cl)cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K21 compound treatment 30800.0 -19800.0 -1.15 25840.0 -16400.0 -1.24 -1.6858 -0.9992 1134325 Maybridge4_002353 COCc1cc(OC(=O)N(C)C)nc2n(C)nc(c3cccs3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K22 compound treatment 23720.0 -26900.0 -1.56 19640.0 -22600.0 -1.71 -2.3077 -0.9989 1310626 Maybridge4_002354 CCOC(=O)CSc1sc(C(=O)OCC)c-2c1S(=O)(=O)N(C)c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K23 mock treatment 37680.0 -12900.0 -0.75 35200.0 -7000.0 -0.53 -0.9029 -0.9859 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 K24 mock treatment 38840.0 -11700.0 -0.68 32840.0 -9360.0 -0.71 -0.9817 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L01 compound treatment 37080.0 -13500.0 -0.78 29960.0 -12200.0 -0.93 -1.208 -0.9964 3064121 Maybridge4_002355 CSc1sc(c2ccn(n2)C(=O)Nc3ccccc3)c4CC(C)(C)CC(=O)c14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L02 compound treatment 46840.0 -3730.0 -0.22 36640.0 -5560.0 -0.42 -0.4506 -0.9521 3178664 Maybridge4_002356 CS(=O)(=N/C=C(\C#N)/S(=O)(=O)c1ccc(cn1)C(F)(F)F)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L03 compound treatment 47320.0 -3250.0 -0.19 34320.0 -7880.0 -0.6 -0.5551 -0.8873 3064122 Maybridge4_002357 CSc1sc(C#N)c(C)c1C(=O)/C=C/N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L04 compound treatment 35320.0 -15300.0 -0.88 31320.0 -10900.0 -0.82 -1.2073 -0.9994 3178665 Maybridge4_002358 CCOC(=O)c1sc(SCCS(=O)(=O)c2ccc(Cl)cc2)c3C(=O)CCCc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L05 compound treatment 29400.0 -21200.0 -1.23 27760.0 -14400.0 -1.09 -1.6404 -0.9983 1438715 Maybridge4_002359 Cc1c(C=C)c(sc1C(=O)Oc2ccccc2)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L06 compound treatment 35400.0 -15200.0 -0.88 29360.0 -12800.0 -0.97 -1.3089 -0.9987 3178666 Maybridge4_002360 CC1(C)CC(=O)c2c(SCCOC(=O)c3ccccc3Cl)sc(C#N)c2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L07 compound treatment 33960.0 -16600.0 -0.96 27160.0 -15000.0 -1.14 -1.4857 -0.9965 3064123 Maybridge4_002361 Cc1nn(Cc2nc(cs2)C(C)(C)C)c(C)c1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L08 compound treatment 41600.0 -8970.0 -0.52 32240.0 -9960.0 -0.75 -0.9008 -0.9835 1009905 Maybridge4_002362 CC(=O)Nc1ccc(Br)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L09 compound treatment 43160.0 -7410.0 -0.43 32280.0 -9920.0 -0.75 -0.8347 -0.9649 3178667 Maybridge4_002363 CSc1sc(c2CCCC(=O)c12)c3ccnc(SCC(=O)c4ccc(Cl)cc4)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L10 compound treatment 41240.0 -9330.0 -0.54 32440.0 -9760.0 -0.74 -0.9048 -0.9882 3064124 Maybridge4_002364 O=S1(=O)CC=C(C1)Sc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L11 compound treatment 40840.0 -9730.0 -0.56 29080.0 -13100.0 -0.99 -1.101 -0.964 3178668 Maybridge4_002365 Cc1cc(C)n(CCS(=O)(=O)c2ccc(Cl)cc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L12 compound treatment 2280.0 -48300.0 -2.8 1880.0 -40300.0 -3.05 -4.1366 -0.9991 3064125 Maybridge4_002366 Clc1ccc(cc1)C(=O)Nc2cc(cs2)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L13 compound treatment 34520.0 -16100.0 -0.93 26280.0 -15900.0 -1.21 -1.5098 -0.9918 3178669 Maybridge4_002367 Cc1csc2sc(c(C)c12)c3ccnc(SCC(=O)NCc4ccccc4)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L14 compound treatment 39880.0 -10700.0 -0.62 29320.0 -12900.0 -0.98 -1.1275 -0.976 1344584 Maybridge4_002368 COC(=O)c1c(C)n2CSCc2c1C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L15 compound treatment 44800.0 -5770.0 -0.33 34080.0 -8120.0 -0.61 -0.6712 -0.9591 3178670 Maybridge4_002369 CN(C)/C=C/C(=O)c1ccsc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L16 compound treatment 20120.0 -30500.0 -1.76 14840.0 -27400.0 -2.07 -2.7121 -0.9968 1542795 Maybridge4_002370 CCCCc1ccc(NC(=O)N=S2CCN(CC2)C(=O)c3ccc(Cl)cc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L17 compound treatment 36520.0 -14100.0 -0.81 27880.0 -14300.0 -1.08 -1.3422 -0.99 1463535 Maybridge4_002371 CN1c2sc(C)c(C)c2C(=C(C(=O)Nc3ccc(Cl)cc3)S1(=O)=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L18 compound treatment 37360.0 -13200.0 -0.77 33160.0 -9040.0 -0.68 -1.0252 -0.9984 1537505 Maybridge4_002372 Cc1occc1C(=O)C(=C(NCc2cccnc2)NCc3cccnc3)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L19 compound treatment 4000.0 -46600.0 -2.7 4400.0 -37800.0 -2.86 -3.9313 -0.9996 3064207 Maybridge4_002373 CS(=O)(=O)c1cc2cc(Cl)ccc2oc1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L20 compound treatment 33000.0 -17600.0 -1.02 24800.0 -17400.0 -1.32 -1.6513 -0.9919 3064208 Maybridge4_002374 FC(F)(F)c1ccc(SC(=O)c2csc(n2)C3COc4ccccc4O3)nc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L21 compound treatment 38800.0 -11800.0 -0.68 41800.0 -401.0 -0.03 -0.5038 -0.7379 3064209 Maybridge4_002375 CN(C)/C=N/C(=O)c1sc(c2C=CCCc12)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L22 compound treatment 44440.0 -6130.0 -0.36 40200.0 -2000.0 -0.15 -0.3584 -0.9278 1320320 Maybridge4_002376 O=C(C1Cc2ccccc2C1)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L23 mock treatment 42640.0 -7930.0 -0.46 36160.0 -6040.0 -0.46 -0.6483 -1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 L24 mock treatment 42160.0 -8410.0 -0.49 39520.0 -2680.0 -0.2 -0.4882 -0.9246 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M01 compound treatment 55640.0 5070.0 0.29 42880.0 679.0 0.05 0.2439 0.8184 3064210 Maybridge4_002377 OC(=O)c1ccc2ccccc2c1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M02 compound treatment 29240.0 -21300.0 -1.24 27000.0 -15200.0 -1.15 -1.6876 -0.9994 3064211 Maybridge4_002378 Clc1ccc(cc1)S(=O)(=O)/C(=C/Nc2cccc(Cl)c2)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M03 compound treatment 36240.0 -14300.0 -0.83 33480.0 -8720.0 -0.66 -1.054 -0.9935 3178671 Maybridge4_002379 COC(=O)c1ccc(Oc2ccc(Cl)cc2Cl)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M04 compound treatment 33000.0 -17600.0 -1.02 27840.0 -14400.0 -1.09 -1.4886 -0.9995 3178672 Maybridge4_002380 CCOC(=O)/C(=C\Nc1ccc(F)c(Cl)c1)/S(=O)(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M05 compound treatment 14560.0 -36000.0 -2.09 12080.0 -30100.0 -2.28 -3.0876 -0.999 3064212 Maybridge4_002381 Clc1ccc(/C=C/C(=O)Nc2cccc(Cl)c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M06 compound treatment 38280.0 -12300.0 -0.71 34000.0 -8200.0 -0.62 -0.9426 -0.9977 3064213 Maybridge4_002382 NNC(=O)CS(=O)(=O)c1ccc(Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M07 compound treatment 29120.0 -21500.0 -1.24 26240.0 -16000.0 -1.21 -1.7332 -0.9999 3178673 Maybridge4_002383 Cc1cc(C)cc(NC(=S)Nc2cc(C)cc(C)c2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M08 compound treatment 27000.0 -23600.0 -1.37 19240.0 -23000.0 -1.74 -2.1947 -0.9929 3178674 Maybridge4_002384 Clc1ccc(SCC(=O)Nc2cscc2S(=O)(=O)c3ccc(Cl)cc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M09 compound treatment 30320.0 -20300.0 -1.17 24360.0 -17800.0 -1.35 -1.7846 -0.9975 1165743 Maybridge4_002385 CCN(CCS(=O)(=O)c1ccc(Cl)cc1)S(=O)(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M10 compound treatment 30080.0 -20500.0 -1.19 26880.0 -15300.0 -1.16 -1.6596 -0.9999 3178675 Maybridge4_002386 Clc1ccccc1NC(=S)Nc2cscc2S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M11 compound treatment 35840.0 -14700.0 -0.85 30160.0 -12000.0 -0.91 -1.2481 -0.9995 1302916 Maybridge4_002387 CC(C)(C)n1nc(cc1NC(=O)Nc2ccccc2)C3CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M12 compound treatment 22520.0 -28100.0 -1.63 19120.0 -23100.0 -1.75 -2.3847 -0.9993 3178676 Maybridge4_002388 COC(=O)c1sc(SC)c(c1C)c2ccn(n2)S(=O)(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M13 compound treatment 37480.0 -13100.0 -0.76 35520.0 -6680.0 -0.51 -0.894 -0.9806 3064215 Maybridge4_002389 COc1c(Cl)scc1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M14 compound treatment 39840.0 -10700.0 -0.62 33160.0 -9040.0 -0.68 -0.9236 -0.9989 3178677 Maybridge4_002390 CC(C)S(=O)(=O)c1csc(C(=O)NN)c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M15 compound treatment 20640.0 -29900.0 -1.73 15840.0 -26400.0 -2.0 -2.6372 -0.9976 1619049 Maybridge4_002391 CC(C)(C)c1ccc(cc1)c2[nH]nc(NC(=O)c3ccccc3Cl)c2Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M16 compound treatment 45120.0 -5450.0 -0.32 32920.0 -9280.0 -0.7 -0.7202 -0.9349 3178678 Maybridge4_002392 CSc1sc(C(=O)O)c(I)c1S(=O)(=O)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M17 compound treatment 28800.0 -21800.0 -1.26 22840.0 -19400.0 -1.47 -1.9283 -0.9972 3178679 Maybridge4_002393 CC(C)(C)c1ccc(cc1)C(=O)C(=C2SCCCS2)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M18 compound treatment 39400.0 -11200.0 -0.65 33400.0 -8800.0 -0.67 -0.9288 -0.9999 3064216 Maybridge4_002394 CS(=O)(=NC(=O)Nc1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M19 compound treatment 38160.0 -12400.0 -0.72 32960.0 -9240.0 -0.7 -1.0031 -0.9999 3178680 Maybridge4_002395 CSc1nc2cc(C)nn2c(c1C#N)c3ccccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M20 compound treatment 40000.0 -10600.0 -0.61 32240.0 -9960.0 -0.75 -0.9663 -0.9947 1447748 Maybridge4_002396 Clc1ccccc1c2csc(CS(=O)(=O)c3cccs3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M21 compound treatment 37120.0 -13500.0 -0.78 29400.0 -12800.0 -0.97 -1.2363 -0.9942 3178681 Maybridge4_002397 CSc1nc(N)n2nc(cc2n1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M22 compound treatment 32680.0 -17900.0 -1.04 27240.0 -15000.0 -1.13 -1.5338 -0.999 3178753 Maybridge4_002398 CN(C)/C=C/C(=O)c1sc(SCc2ccc(Cl)cc2)c3C(=O)CC(C)(C)Cc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M23 mock treatment 48720.0 -1850.0 -0.11 33440.0 -8760.0 -0.66 -0.5448 -0.811 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 M24 mock treatment 47040.0 -3530.0 -0.2 40800.0 -1400.0 -0.11 -0.2197 -0.9532 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N01 compound treatment 26240.0 -24300.0 -1.41 25840.0 -16400.0 -1.24 -1.8726 -0.9979 3064217 Maybridge4_002399 CCOC(=O)c1sc2sc(C(=O)OCC)c(c3ccc(Cl)cc3)c2c1N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N02 compound treatment 39520.0 -11100.0 -0.64 38040.0 -4160.0 -0.31 -0.6755 -0.9466 3064244 Maybridge4_002400 CCOC(=O)NS(=O)(=O)c1ccc(s1)c2cc(n(C)n2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N03 compound treatment 33600.0 -17000.0 -0.98 27000.0 -15200.0 -1.15 -1.509 -0.9969 3064245 Maybridge4_002401 CSc1scc2CC(C)(C)CC(=O)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N04 compound treatment 21680.0 -28900.0 -1.67 19240.0 -23000.0 -1.74 -2.4127 -0.9998 3064246 Maybridge4_002402 CC1(C)CCc2cc(ccc2O1)C3SCCS3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N05 compound treatment 41320.0 -9250.0 -0.54 33720.0 -8480.0 -0.64 -0.833 -0.996 3064248 Maybridge4_002403 Cc1nn(CC(=S)N)c(C)c1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N06 compound treatment 43480.0 -7090.0 -0.41 37960.0 -4240.0 -0.32 -0.5176 -0.9925 1138975 Maybridge4_002404 CC(C)S(=O)(=O)c1cscc1N2C(=O)c3ccccc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N07 compound treatment 25920.0 -24700.0 -1.43 23200.0 -19000.0 -1.44 -2.027 -1.0 3064249 Maybridge4_002405 Fc1cccc(NC(=S)N(CCS(=O)(=O)c2ccc(Cl)cc2)Cc3cccs3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N08 compound treatment 38520.0 -12100.0 -0.7 35040.0 -7160.0 -0.54 -0.8771 -0.9922 3064250 Maybridge4_002406 Clc1ccc(C(=O)C2C(=O)CCC(C2=O)c3ccccc3)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N09 compound treatment 31000.0 -19600.0 -1.13 21240.0 -21000.0 -1.59 -1.9238 -0.9864 3064251 Maybridge4_002407 CSc1sc(c2CC(C)(C)CC(=O)c12)c3ccnc(SCC(=O)C(C)(C)C)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N10 compound treatment 41480.0 -9090.0 -0.53 31960.0 -10200.0 -0.78 -0.9207 -0.9823 1318871 Maybridge4_002408 Cn1ccnc1SCCS(=O)(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N11 compound treatment 27040.0 -23500.0 -1.36 23320.0 -18900.0 -1.43 -1.9747 -0.9997 1250473 Maybridge4_002409 CCOC(=O)c1sc(SCc2ccccc2)c3c1-c4sccc4N(C)S3(=O)=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N12 compound treatment 40680.0 -9890.0 -0.57 39040.0 -3160.0 -0.24 -0.5745 -0.9249 3064253 Maybridge4_002410 FC(F)(F)c1cc(cc(c1)S(=O)(=O)/N=S\2/CCC3(C2)OCCO3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N13 compound treatment 43640.0 -6930.0 -0.4 33480.0 -8720.0 -0.66 -0.7508 -0.9716 1662782 Maybridge4_002411 CSc1sc(c2nc(cs2)C(C)(C)C)c3CCCC(=O)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N14 compound treatment 30800.0 -19800.0 -1.15 25080.0 -17100.0 -1.3 -1.7264 -0.9981 1607185 Maybridge4_002412 Clc1ccc(cc1)C(=O)N=S2CCN(CC2)C(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N15 compound treatment 20160.0 -30400.0 -1.76 14120.0 -28100.0 -2.13 -2.749 -0.9957 3178754 Maybridge4_002413 COC(=O)C1=C(CSC1)Nc2ccc(OC(=O)c3cccc(c3)C(F)(F)F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N16 compound treatment 23800.0 -26800.0 -1.55 24440.0 -17800.0 -1.34 -2.0475 -0.9975 1495489 Maybridge4_002414 Clc1ccc(OC(=O)c2cccnc2SCCS(=O)(=O)c3ccccc3)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N17 compound treatment 36440.0 -14100.0 -0.82 38120.0 -4080.0 -0.31 -0.7974 -0.9112 3178755 Maybridge4_002415 CSc1sc(C(=O)NN)c2CCC=Cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N18 compound treatment 36440.0 -14100.0 -0.82 33840.0 -8360.0 -0.63 -1.0265 -0.9919 3178756 Maybridge4_002416 CS(=O)(=NS(=O)(=O)c1cccs1)c2ccc(OC(=O)c3ccc(Cl)cc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N19 compound treatment 42400.0 -8170.0 -0.47 33080.0 -9120.0 -0.69 -0.823 -0.9831 3064254 Maybridge4_002417 CS(=O)(=O)/C(=C/Nc1cnccn1)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N20 compound treatment 29840.0 -20700.0 -1.2 25400.0 -16800.0 -1.27 -1.7486 -0.9996 1627111 Maybridge4_002418 O=C(SCc1cccs1)c2csc(n2)C3COc4ccccc4O3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N21 compound treatment 44160.0 -6410.0 -0.37 32720.0 -9480.0 -0.72 -0.7702 -0.953 3064255 Maybridge4_002419 FC(F)(F)Oc1ccc(cc1)S(=O)(=O)CCN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N22 compound treatment 34360.0 -16200.0 -0.94 29120.0 -13100.0 -0.99 -1.3644 -0.9997 3178757 Maybridge4_002420 Clc1ccc(cc1)c2cc(NC(=O)C3Cc4ccccc4C3)[nH]n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N23 mock treatment 38480.0 -12100.0 -0.7 35640.0 -6560.0 -0.5 -0.8466 -0.9858 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 N24 mock treatment 42000.0 -8570.0 -0.5 41520.0 -681.0 -0.05 -0.3877 -0.7764 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O01 compound treatment 47480.0 -3090.0 -0.18 38840.0 -3360.0 -0.25 -0.3066 -0.9853 1259648 Maybridge4_002421 COc1ccc(NC(=O)C(C(=O)Nc2ccc(OC)cc2)C3(CC4CC5CC(C4)C3)C5)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O02 compound treatment 47480.0 -3090.0 -0.18 39560.0 -2640.0 -0.2 -0.2681 -0.9985 3064256 Maybridge4_002422 FC(F)(F)c1cc(N/C=C(\C#N)/S(=O)(=O)c2ccccn2)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O03 compound treatment 39320.0 -11300.0 -0.65 33760.0 -8440.0 -0.64 -0.9128 -0.9999 1743228 Maybridge4_002423 Cc1ccc(Nc2cc(O)nn2C)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O04 compound treatment 35320.0 -15300.0 -0.88 28320.0 -13900.0 -1.05 -1.3678 -0.9963 3064257 Maybridge4_002424 CCn1c(S)nc2ccccc2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O05 compound treatment 19600.0 -31000.0 -1.79 18880.0 -23300.0 -1.77 -2.5171 -1.0 3178758 Maybridge4_002425 Cc1c(C)c(C)c(CSc2ccccc2N)c(C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O06 compound treatment 46640.0 -3930.0 -0.23 44320.0 2120.0 0.16 -0.0477 -0.1712 3064258 Maybridge4_002426 CS/C(=C(\C#N)/C(=O)C1CC1)/N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O07 compound treatment 48800.0 -1770.0 -0.1 36240.0 -5960.0 -0.45 -0.3917 -0.8464 1286597 Maybridge4_002427 O=S(=O)(CCN1CCSCC1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O08 compound treatment 42760.0 -7810.0 -0.45 32200.0 -10000.0 -0.76 -0.8554 -0.9698 3064259 Maybridge4_002428 Clc1ccccc1C(=O)Nc2cscc2S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O09 compound treatment 39480.0 -11100.0 -0.64 28400.0 -13800.0 -1.04 -1.1931 -0.9728 3178759 Maybridge4_002429 O=S(=O)(CCSc1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O10 compound treatment 34200.0 -16400.0 -0.95 29120.0 -13100.0 -0.99 -1.3709 -0.9998 1558086 Maybridge4_002430 COC(=O)C1=C(CSC1)Nc2ccc(F)cc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O11 compound treatment 30760.0 -19800.0 -1.15 28600.0 -13600.0 -1.03 -1.5397 -0.9985 3064260 Maybridge4_002431 Cc1cc(C)n2nc(cc2n1)c3ccc(cc3)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O12 compound treatment 1800.0 -48800.0 -2.83 1560.0 -40600.0 -3.08 -4.1734 -0.9991 3178760 Maybridge4_002432 CC(C)S(=O)(=O)c1csc(C(=O)OCC(=O)c2ccc(Cl)cc2)c1N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O13 compound treatment 34880.0 -15700.0 -0.91 26400.0 -15800.0 -1.2 -1.4886 -0.9908 3064262 Maybridge4_002433 Clc1ccc(cc1)S(=O)(=O)/C(=C/N2CCCCC2)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O14 compound treatment 51280.0 708.0 0.04 43960.0 1760.0 0.13 0.1231 0.8839 3178761 Maybridge4_002434 Fc1ccc(NC(=O)c2cccnc2Sc3cccs3)c(F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O15 compound treatment 8640.0 -41900.0 -2.43 7920.0 -34300.0 -2.59 -3.5528 -0.9995 3064263 Maybridge4_002435 Nc1nc(Sc2ccc(Cl)cc2)c(C#N)c(c1C#N)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O16 compound treatment 40320.0 -10300.0 -0.59 30800.0 -11400.0 -0.86 -1.0303 -0.9834 3178762 Maybridge4_002436 CSc1scc(c1C#N)c2cc(Cl)cc(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O17 compound treatment 40920.0 -9650.0 -0.56 35280.0 -6920.0 -0.52 -0.7659 -0.9995 3064280 Maybridge4_002437 O=C(C(=C1SCCCS1)C#N)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O18 compound treatment 33200.0 -17400.0 -1.01 32160.0 -10000.0 -0.76 -1.2492 -0.9904 3064281 Maybridge4_002438 CN(/N=C(\C#N)/C(=O)C1CC1)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O19 compound treatment 46160.0 -4410.0 -0.26 35920.0 -6280.0 -0.48 -0.517 -0.9577 1358615 Maybridge4_002439 COCc1cc(OC(=O)N(C)C)nc2n(C)nc(C)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O20 compound treatment 17440.0 -33100.0 -1.92 16920.0 -25300.0 -1.91 -2.7105 -1.0 1379175 Maybridge4_002440 Cn1ccc(n1)c2cccc(NC(=O)Nc3ccccc3)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O21 compound treatment 41960.0 -8610.0 -0.5 33560.0 -8640.0 -0.65 -0.8154 -0.9911 3064282 Maybridge4_002441 CSc1c(C#N)c(nn1CNC(=O)Nc2ccccc2C(F)(F)F)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O22 compound treatment 39320.0 -11300.0 -0.65 38320.0 -3880.0 -0.29 -0.6687 -0.9352 3064283 Maybridge4_002442 CCOC(=O)c1sc(SCc2c(Cl)cccc2Cl)c(c1N)S(=O)(=O)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O23 mock treatment 47360.0 -3210.0 -0.19 39080.0 -3120.0 -0.24 -0.2987 -0.993 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 O24 mock treatment 47280.0 -3290.0 -0.19 43080.0 879.0 0.07 -0.0879 -0.4349 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P01 compound treatment 54600.0 4030.0 0.23 51520.0 9320.0 0.71 0.6638 0.8934 3064285 Maybridge4_002443 Nc1c(C#N)sc2sc(C#N)c(c3ccco3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P02 compound treatment 35960.0 -14600.0 -0.85 32640.0 -9560.0 -0.72 -1.1104 -0.997 3064286 Maybridge4_002444 CC(C)(C)c1ncc(c(N)n1)S(=O)(=O)c2ccc(cn2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P03 compound treatment 29680.0 -20900.0 -1.21 26680.0 -15500.0 -1.17 -1.6867 -0.9999 3178763 Maybridge4_002445 CCOC(=O)c1sc(SC)c2C(=O)CC(Cc12)c3ccc(OC)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P04 compound treatment 41840.0 -8730.0 -0.51 39400.0 -2800.0 -0.21 -0.5077 -0.9255 3178764 Maybridge4_002446 CCOC(=O)c1sc(Sc2ccc(cn2)C(F)(F)F)c3C(=O)CC(C)(C)Cc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P05 compound treatment 41200.0 -9370.0 -0.54 35760.0 -6440.0 -0.49 -0.7287 -0.9986 1299033 Maybridge4_002447 CS(=O)(=O)c1sc(C(=O)O)c2CCC=Cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P06 compound treatment 42760.0 -7810.0 -0.45 32840.0 -9360.0 -0.71 -0.8211 -0.9766 1436320 Maybridge4_002448 Cc1cc(C)n(n1)c2ncc(c(N)n2)S(=O)(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P07 compound treatment 27400.0 -23200.0 -1.34 21480.0 -20700.0 -1.57 -2.0584 -0.997 3178765 Maybridge4_002449 CSc1scc2CCc3cn(nc3-c12)C(=O)c4cccc(c4)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P08 compound treatment 51200.0 628.0 0.04 36520.0 -5680.0 -0.43 -0.2784 -0.645 3178766 Maybridge4_002450 CS(=O)(=NC(=O)NC(=O)c1ccc(Cl)cc1)c2ccc(cn2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P09 compound treatment 26400.0 -24200.0 -1.4 22400.0 -19800.0 -1.5 -2.0501 -0.9994 3064288 Maybridge4_002451 O=S(=O)(N1CCCCC1)c2ccc(s2)c3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P10 compound treatment 39720.0 -10900.0 -0.63 33320.0 -8880.0 -0.67 -0.92 -0.9994 3064289 Maybridge4_002452 COC(=O)c1cnc(S)n1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P11 compound treatment 40960.0 -9610.0 -0.56 36160.0 -6040.0 -0.46 -0.7172 -0.9952 3178767 Maybridge4_002453 FC(F)(F)c1cc(NC(=S)NC(=O)Oc2ccccc2)cc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P12 compound treatment 35160.0 -15400.0 -0.89 31440.0 -10800.0 -0.81 -1.2074 -0.9989 3064290 Maybridge4_002454 Cc1ccc(SCC(=O)c2ccc(CC(=O)O)s2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P13 compound treatment 37040.0 -13500.0 -0.78 35440.0 -6760.0 -0.51 -0.9163 -0.9786 3178768 Maybridge4_002455 CS(=O)(=NS(=O)(=O)c1ccc(OC(F)(F)F)cc1)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P14 compound treatment 36480.0 -14100.0 -0.82 33680.0 -8520.0 -0.65 -1.0334 -0.9932 3064291 Maybridge4_002456 CN(C)/C=C/C(=O)c1ccc2OCCc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P15 compound treatment 18040.0 -32500.0 -1.88 17200.0 -25000.0 -1.89 -2.671 -1.0 3178769 Maybridge4_002457 Cc1cc2ncc(c(C)n2n1)c3ccnc(SCc4c(Cl)cccc4Cl)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P16 compound treatment 39120.0 -11500.0 -0.66 31880.0 -10300.0 -0.78 -1.0216 -0.9967 3064292 Maybridge4_002458 CS(=O)(=O)CCSc1ncccc1C(=O)NCc2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P17 compound treatment 23640.0 -26900.0 -1.56 23000.0 -19200.0 -1.45 -2.1311 -0.9994 1476633 Maybridge4_002459 CCOC(=O)c1sc(N2CCCCC2)c3C(=O)CC(C)(C)Cc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P18 compound treatment 36880.0 -13700.0 -0.79 33200.0 -9000.0 -0.68 -1.0427 -0.9971 3064293 Maybridge4_002460 OC(=O)C1Cc2ccccc2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P19 compound treatment 33200.0 -17400.0 -1.01 34520.0 -7680.0 -0.58 -1.1229 -0.966 3178770 Maybridge4_002461 FC(F)(F)c1ccc(nc1)S(=O)(=O)/C(=C/Nc2cnccn2)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P20 compound treatment 7880.0 -42700.0 -2.47 4840.0 -37400.0 -2.83 -3.7488 -0.9978 1356891 Maybridge4_002462 CCOC(=O)CC1Sc2ccccc2N=C1SCC(=O)Nc3ccc(Cl)cc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P21 compound treatment 26040.0 -24500.0 -1.42 25120.0 -17100.0 -1.29 -1.9193 -0.9989 3064294 Maybridge4_002463 Clc1ccc(Sc2ccc(s2)c3ccccn3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P22 compound treatment 19800.0 -30800.0 -1.78 17280.0 -24900.0 -1.89 -2.5946 -0.9996 1623679 Maybridge4_002464 Cc1ccc(NC(=O)c2ccc3OCCc3c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P23 mock treatment 38800.0 -11800.0 -0.68 34240.0 -7960.0 -0.6 -0.9084 -0.9981 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2055 P24 mock treatment 47720.0 -2850.0 -0.17 37960.0 -4240.0 -0.32 -0.3439 -0.9523 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A01 compound treatment 52880.0 11300.0 0.65 59440.0 13900.0 1.05 1.2077 0.9739 3178771 Maybridge4_002465 FC(F)(F)c1ccc(NC(=O)c2ccc3OCCc3c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A02 compound treatment 41320.0 -255.0 -0.01 49120.0 3590.0 0.27 0.1818 0.6677 3178772 Maybridge4_002466 COc1cc(nc2ccc(C)c(NC(=O)Nc3ccc(OC(F)(F)F)cc3)c12)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A03 compound treatment 43880.0 2310.0 0.13 53360.0 7830.0 0.59 0.5136 0.8452 1345781 Maybridge4_002467 O=C1N(CC2COc3ccccc3O2)C(=O)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A04 compound treatment 46360.0 4790.0 0.28 54680.0 9150.0 0.69 0.6858 0.9192 1377469 Maybridge4_002468 CN(C)CC#Cc1cncc(c1)C(=O)NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A05 compound treatment 41880.0 305.0 0.02 43680.0 -1850.0 -0.14 -0.0865 -0.6129 1734397 Maybridge4_002469 Brc1cc2CCOc2c(c1)C(=O)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A06 compound treatment 37800.0 -3780.0 -0.22 36520.0 -9010.0 -0.68 -0.6368 -0.8893 3178773 Maybridge4_002470 FC(F)(F)c1ccc2cc(CSc3ccc(Cl)cc3)ccc2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A07 compound treatment 20600.0 -21000.0 -1.22 23960.0 -21600.0 -1.63 -2.0138 -0.9894 3064295 Maybridge4_002471 COc1ccc(OC(=O)c2csc(COc3ccc4nonc4c3)n2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A08 compound treatment 43640.0 2070.0 0.12 47280.0 1750.0 0.13 0.1783 0.9987 1124957 Maybridge4_002472 Fc1ccc(cc1)S(=O)(=O)CCN2CCC(CC2)n3cccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A09 compound treatment 31360.0 -10200.0 -0.59 35200.0 -10300.0 -0.78 -0.9713 -0.9906 3064326 Maybridge4_002473 Cc1nn(Cc2ccc(o2)C(=O)Sc3ccc(cn3)C(F)(F)F)c(C)c1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A10 compound treatment 42720.0 1150.0 0.07 48040.0 2510.0 0.19 0.1813 0.9006 1618157 Maybridge4_002474 CCOC(=O)c1c(SC)nc2ccc(Cl)cc2c1N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A11 compound treatment 44600.0 3030.0 0.18 53200.0 7670.0 0.58 0.5345 0.8813 1711585 Maybridge4_002475 CCOC(=O)NC(=O)c1cn(Cc2cccs2)c(=O)n(C)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A12 compound treatment 32320.0 -9260.0 -0.54 30240.0 -15300.0 -1.16 -1.1975 -0.9389 3064327 Maybridge4_002476 FC(F)(F)c1cc(N2CCN(CC2)C(=O)c3cccs3)c4ccccc4n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A13 compound treatment 41240.0 -335.0 -0.02 46040.0 511.0 0.04 0.0136 0.3151 3064329 Maybridge4_002477 Cc1ccc(cc1)S(=O)(=O)NCCSc2cc(nc3ccccc23)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A14 compound treatment 39440.0 -2140.0 -0.12 40640.0 -4890.0 -0.37 -0.3491 -0.8948 3064330 Maybridge4_002478 Clc1ccc(NC(=O)OCC#Cc2ccc(C#N)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A15 compound treatment 18760.0 -22800.0 -1.32 17000.0 -28500.0 -2.16 -2.4617 -0.9723 3064331 Maybridge4_002479 COC(=O)c1scc2c(SCc3ccccc3)cc(nc12)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A16 compound treatment 41000.0 -575.0 -0.03 45680.0 151.0 0.01 -0.0155 -0.4389 3178850 Maybridge4_002480 CCCNC(=O)Nc1ccc(OC(F)(F)F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A17 compound treatment 46480.0 4910.0 0.28 48240.0 2710.0 0.21 0.3461 0.9872 1220133 Maybridge4_002481 COC(=O)c1sccc1n2cc(C#N)c(=O)n(C)c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A18 compound treatment 31120.0 -10500.0 -0.61 38600.0 -6930.0 -0.52 -0.7992 -0.9974 1288518 Maybridge4_002482 O=c1[nH]nc(CSc2ccccn2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A19 compound treatment 43360.0 1790.0 0.1 50120.0 4590.0 0.35 0.3189 0.8794 1196923 Maybridge4_002483 Cn1c(=O)c(cn(c2ccccc2)c1=O)C(=S)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A20 compound treatment 47520.0 5950.0 0.34 50720.0 5190.0 0.39 0.5214 0.9978 3178851 Maybridge4_002484 COc1ccc(NC(=O)N(Cc2ccccc2)C(=O)CC#N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A21 compound treatment 34880.0 -6700.0 -0.39 39480.0 -6050.0 -0.46 -0.598 -0.9966 1562266 Maybridge4_002485 Clc1ccccc1C(=O)CSC2=NCCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A22 compound treatment 39160.0 -2420.0 -0.14 44480.0 -1050.0 -0.08 -0.1551 -0.964 3064332 Maybridge4_002486 FC(F)(F)c1cc(Oc2ccc(Cl)cc2)c3cc(Cl)ccc3n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A23 mock treatment 48520.0 6950.0 0.4 49400.0 3870.0 0.29 0.4917 0.9879 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 A24 mock treatment 59320.0 17700.0 1.03 55520.0 9990.0 0.76 1.2618 0.9886 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B01 compound treatment 22640.0 -18900.0 -1.1 26000.0 -19500.0 -1.48 -1.821 -0.9892 1234192 Maybridge4_002487 Cc1nc(ncc1S(=O)(=O)c2ccc(Cl)cc2)C3COc4ccccc4O3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B02 compound treatment 49640.0 8070.0 0.47 56640.0 11100.0 0.84 0.9251 0.9615 3064333 Maybridge4_002488 COC(=O)c1cc2cc(Br)ccc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B03 compound treatment 39280.0 -2300.0 -0.13 47240.0 1710.0 0.13 -0.0024 -0.0131 1523364 Maybridge4_002489 Cc1ccccc1NC(=O)NCCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B04 compound treatment 32880.0 -8700.0 -0.5 30200.0 -15300.0 -1.16 -1.1767 -0.9302 3064334 Maybridge4_002490 Cc1c(sc2ccc(Cl)cc12)C(=O)COC(=O)c3ccccc3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B05 compound treatment 39480.0 -2100.0 -0.12 51280.0 5750.0 0.44 0.222 0.4912 3178852 Maybridge4_002491 Cc1cccc(C)c1NC(=O)N(Cc2ccccc2)C(=O)CC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B06 compound treatment 45480.0 3910.0 0.23 48160.0 2630.0 0.2 0.3008 0.998 3064335 Maybridge4_002492 Cc1c(sc2ccccc12)c3ccnn3C(=O)Nc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B07 compound treatment 41760.0 185.0 0.01 43920.0 -1610.0 -0.12 -0.0785 -0.6424 1235231 Maybridge4_002493 COC(=O)c1ccc(CN(C(=O)C)C(=O)Nc2ccc(cc2C)C(=O)OC)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B08 compound treatment 45200.0 3630.0 0.21 53600.0 8070.0 0.61 0.5805 0.8986 3178853 Maybridge4_002494 Clc1ccccc1NC(=S)N2CCOC2c3c[nH]c4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B09 compound treatment 11560.0 -30000.0 -1.74 15880.0 -29600.0 -2.24 -2.8166 -0.9921 3064336 Maybridge4_002495 C=CCn1c(SCc2ccccc2)nnc1c3ccc4ncccc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B10 compound treatment 39000.0 -2580.0 -0.15 40600.0 -4930.0 -0.37 -0.3693 -0.9191 3064337 Maybridge4_002496 O=C(CCSc1ccccc1)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B11 compound treatment 11600.0 -30000.0 -1.74 14760.0 -30800.0 -2.33 -2.8749 -0.9896 3178854 Maybridge4_002497 CC(C)n1c(nc2cc(ccc12)C(=O)Nc3ccc(Cl)cc3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B12 compound treatment 25680.0 -15900.0 -0.92 27160.0 -18400.0 -1.39 -1.6344 -0.98 1241391 Maybridge4_002498 Clc1cccc(NC(=O)OC2CCCCc3cccnc23)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B13 compound treatment 30280.0 -11300.0 -0.65 33160.0 -12400.0 -0.94 -1.1248 -0.9847 1376937 Maybridge4_002499 CCc1ccc2[nH]c(cc2c1)C(=O)NCCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B14 compound treatment 24200.0 -17400.0 -1.01 28560.0 -17000.0 -1.28 -1.6201 -0.9927 3178855 Maybridge4_002500 FC(F)(F)COc1ccc(Sc2ncccn2)c(OCC(F)(F)F)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B15 compound treatment 33440.0 -8140.0 -0.47 40160.0 -5370.0 -0.41 -0.6206 -0.9973 1581778 Maybridge4_002501 Clc1ccc(cc1)c2ccc(s2)C(=O)NC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B16 compound treatment 29680.0 -11900.0 -0.69 30840.0 -14700.0 -1.11 -1.2735 -0.9735 1626834 Maybridge4_002502 C(N1CCC(=N1)c2ccco2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B17 compound treatment 33120.0 -8460.0 -0.49 36520.0 -9010.0 -0.68 -0.8286 -0.9868 3064338 Maybridge4_002503 O=C(NC(=S)NCc1ccccc1)/C=C/c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B18 compound treatment 46040.0 4470.0 0.26 47760.0 2230.0 0.17 0.3023 0.9787 3178856 Maybridge4_002504 OCCn1nc(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccccc3c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B19 compound treatment 44720.0 3150.0 0.18 54400.0 8870.0 0.67 0.6037 0.8676 1406037 Maybridge4_002505 COc1ccc(cc1)c2csc(n2)c3ccc(OC)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B20 compound treatment 46600.0 5030.0 0.29 53720.0 8190.0 0.62 0.6443 0.9406 1528457 Maybridge4_002506 COc1ccc(cc1)c2nn(CCC#N)c(=O)[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B21 compound treatment 45040.0 3470.0 0.2 49360.0 3830.0 0.29 0.347 0.9839 3064339 Maybridge4_002507 Cc1ccc(CC(=O)c2cccnc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B22 compound treatment 33440.0 -8140.0 -0.47 38320.0 -7210.0 -0.55 -0.7191 -0.9973 3178857 Maybridge4_002508 CCOC(=O)NC(=S)N1C(C)CCCC1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B23 mock treatment 52880.0 11300.0 0.65 57720.0 12200.0 0.92 1.1157 0.9859 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 B24 mock treatment 46400.0 4830.0 0.28 57920.0 12400.0 0.94 0.8609 0.8796 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C01 compound treatment 45960.0 4390.0 0.25 52280.0 6750.0 0.51 0.541 0.948 3178858 Maybridge4_002509 Cn1c(S)nnc1C2COc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C02 compound treatment 40760.0 -815.0 -0.05 44840.0 -689.0 -0.05 -0.0703 -0.9988 3064341 Maybridge4_002510 CCOC(=O)c1cncc(C#CCOC(=O)Nc2cc(Cl)cc(Cl)c2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C03 compound treatment 43600.0 2030.0 0.12 46320.0 791.0 0.06 0.1253 0.9513 1514783 Maybridge4_002511 Clc1ccc(cc1)C(=O)NCC2COc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C04 compound treatment 37680.0 -3900.0 -0.23 41160.0 -4370.0 -0.33 -0.3934 -0.9826 3064342 Maybridge4_002512 CSc1nn(cc1c2nc(cs2)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C05 compound treatment 43160.0 1590.0 0.09 53200.0 7670.0 0.58 0.4755 0.8089 3064366 Maybridge4_002513 COc1cccn(CC(=O)NN)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C06 compound treatment 32320.0 -9260.0 -0.54 40880.0 -4650.0 -0.35 -0.628 -0.9791 3064367 Maybridge4_002514 Clc1ccc(Cl)c(c1)S(=O)(=O)n2ccc(n2)c3ccc(Br)s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C07 compound treatment 40480.0 -1100.0 -0.06 48400.0 2870.0 0.22 0.1088 0.4806 1600605 Maybridge4_002515 Clc1ccc(NC(=O)c2csc(COc3ccc4nonc4c3)n2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C08 compound treatment 43040.0 1470.0 0.08 50920.0 5390.0 0.41 0.3486 0.8363 1505462 Maybridge4_002516 Cc1ccc(cc1)S(=O)(=O)CCN2CCC(CC2)n3cccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C09 compound treatment 36000.0 -5580.0 -0.32 39680.0 -5850.0 -0.44 -0.5414 -0.988 3064368 Maybridge4_002517 CSc1nc2ccc(NS(=O)(=O)c3ccccc3C(F)(F)F)cc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C10 compound treatment 30120.0 -11500.0 -0.66 40400.0 -5130.0 -0.39 -0.7438 -0.9674 3064369 Maybridge4_002518 CCOC(=O)c1c(SC)nc2c(cccc2c1N3CCCC3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C11 compound treatment 44360.0 2790.0 0.16 47760.0 2230.0 0.17 0.2335 0.9997 3064371 Maybridge4_002519 Cn1c(S)nnc1CSc2cc(nc3ccccc23)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C12 compound treatment 27720.0 -13900.0 -0.8 33080.0 -12400.0 -0.94 -1.2339 -0.9968 3064373 Maybridge4_002520 FC(F)(F)c1cccc(c1)N2C(=O)C3SCCN3C2=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C13 compound treatment 34240.0 -7340.0 -0.42 39440.0 -6090.0 -0.46 -0.6264 -0.9992 3178859 Maybridge4_002521 O=C(Nc1ccccc1)OCC#Cc2ccc(s2)c3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C14 compound treatment 36720.0 -4860.0 -0.28 39320.0 -6210.0 -0.47 -0.5312 -0.9699 3064374 Maybridge4_002522 FC(F)(F)Oc1ccc(NC(=O)OCC#Cc2ccc(C#N)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C15 compound treatment 14960.0 -26600.0 -1.54 18760.0 -26800.0 -2.03 -2.5231 -0.9909 1566879 Maybridge4_002523 CCOC(=O)Cn1c(=O)c(cn(C(C)C)c1=O)c2nc(cs2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C16 compound treatment 12040.0 -29500.0 -1.71 12560.0 -33000.0 -2.5 -2.9746 -0.9831 1528772 Maybridge4_002524 Cc1ccc(OC(=O)c2c(nnc3ccccc23)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C17 compound treatment 34680.0 -6900.0 -0.4 44800.0 -729.0 -0.06 -0.3215 -0.7972 1617239 Maybridge4_002525 Clc1ccc(Cn2ccnc2COC(=O)Nc3ccc(Cl)cc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C18 compound treatment 41000.0 -575.0 -0.03 43920.0 -1610.0 -0.12 -0.1097 -0.8686 1164357 Maybridge4_002526 COC(=O)CSCc1n[nH]c(=O)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C19 compound treatment 41800.0 225.0 0.01 45000.0 -529.0 -0.04 -0.0191 -0.4534 3178860 Maybridge4_002527 Cn1c(=O)c(cn(c2ccccc2)c1=O)/C(=N/O)/N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C20 compound treatment 38040.0 -3540.0 -0.2 50440.0 4910.0 0.37 0.118 0.2781 3178861 Maybridge4_002528 Fc1cccc(NC(=O)N(Cc2ccccc2)C(=O)CC#N)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C21 compound treatment 40480.0 -1100.0 -0.06 43960.0 -1570.0 -0.12 -0.1288 -0.9569 1734152 Maybridge4_002529 CC(C)(C)OC(=O)N1CCN(CCNC(=O)c2ccc(Cl)cc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C22 compound treatment 23840.0 -17700.0 -1.03 24600.0 -20900.0 -1.58 -1.8468 -0.978 1710452 Maybridge4_002530 COc1ccc(NC(=O)Nc2ccc(OC)c(OC3CCCC3)c2)cc1OC4CCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C23 mock treatment 46880.0 5310.0 0.31 52280.0 6750.0 0.51 0.5787 0.9704 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 C24 mock treatment 45440.0 3870.0 0.22 53080.0 7550.0 0.57 0.5625 0.9163 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D01 compound treatment 43600.0 2030.0 0.12 51680.0 6150.0 0.47 0.4122 0.8584 3064376 Maybridge4_002531 Cc1ccccc1NC(=O)N(Cc2cccs2)C(=O)CC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D02 compound treatment 8840.0 -32700.0 -1.9 11240.0 -34300.0 -2.6 -3.1764 -0.9881 3178862 Maybridge4_002532 Cc1nc2ccc(NS(=O)(=O)c3ccccc3C(F)(F)F)cc2o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D03 compound treatment 32560.0 -9020.0 -0.52 45000.0 -529.0 -0.04 -0.3976 -0.7591 3064377 Maybridge4_002533 FC(F)(F)c1cccc(NC(=S)Nc2cc(n[nH]2)c3cccs3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D04 compound treatment 33880.0 -7700.0 -0.45 43600.0 -1930.0 -0.15 -0.4185 -0.8921 3178863 Maybridge4_002534 Cc1nc(cs1)c2sc3ccc(Cl)cc3c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D05 compound treatment 35120.0 -6460.0 -0.37 46000.0 471.0 0.04 -0.2392 -0.6368 1387292 Maybridge4_002535 CCCOc1cc(ccc1OC)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D06 compound treatment 42040.0 465.0 0.03 46920.0 1390.0 0.11 0.0935 0.8603 3064378 Maybridge4_002536 Cc1c(sc2ccccc12)c3ccnn3C(=O)c4ccc(cc4)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D07 compound treatment 32720.0 -8860.0 -0.51 35440.0 -10100.0 -0.76 -0.9028 -0.9813 1130276 Maybridge4_002537 CSc1ccccc1CNC(=O)NC2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D08 compound treatment 26320.0 -15300.0 -0.88 31040.0 -14500.0 -1.1 -1.4005 -0.9943 3064379 Maybridge4_002538 FC(F)(F)c1ccc(CSc2nccc(n2)c3cccnc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D09 compound treatment 38000.0 -3580.0 -0.21 43320.0 -2210.0 -0.17 -0.2647 -0.9944 3178864 Maybridge4_002539 CCOC(=O)CSc1nnc(c2ccc3ncccc3c2)n1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D10 compound treatment 30640.0 -10900.0 -0.63 33400.0 -12100.0 -0.92 -1.0972 -0.9836 3178865 Maybridge4_002540 Cc1c(sc2ccccc12)C(=S)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D11 compound treatment 39520.0 -2060.0 -0.12 42280.0 -3250.0 -0.25 -0.2581 -0.9446 3064380 Maybridge4_002541 CC(C)n1c(nc2cc(ccc12)C(=O)N3CCOCC3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D12 compound treatment 35800.0 -5780.0 -0.33 38920.0 -6610.0 -0.5 -0.5903 -0.9809 1150832 Maybridge4_002542 Nc1nccc(n1)c2ccc(NC(=O)Nc3ccccc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D13 compound treatment 29720.0 -11900.0 -0.69 34880.0 -10600.0 -0.81 -1.0556 -0.9968 3064381 Maybridge4_002543 CCc1ccc2[nH]c(cc2c1)C(=O)Nc3ccc(c(C#N)c3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D14 compound treatment 37880.0 -3700.0 -0.21 42720.0 -2810.0 -0.21 -0.3017 -1.0 3178947 Maybridge4_002544 FC(F)(F)COc1ccc(SCc2ccccc2)c(OCC(F)(F)F)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D15 compound treatment 31400.0 -10200.0 -0.59 37680.0 -7850.0 -0.59 -0.8369 -1.0 1264919 Maybridge4_002545 CC(C)(C)c1ccc(s1)C(=O)OCc2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D16 compound treatment 39360.0 -2220.0 -0.13 46080.0 551.0 0.04 -0.0612 -0.4538 3064382 Maybridge4_002546 CN1CCC(=N1)/C=C/c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D17 compound treatment 36600.0 -4980.0 -0.29 42920.0 -2610.0 -0.2 -0.3434 -0.983 3178948 Maybridge4_002547 O=C(NC(=S)N1CCCCC1)/C=C/c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D18 compound treatment 40040.0 -1540.0 -0.09 43560.0 -1970.0 -0.15 -0.1683 -0.9696 3064383 Maybridge4_002548 Cn1nc(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccccc3c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D19 compound treatment 74640.0 33100.0 1.92 79080.0 33600.0 2.54 3.1504 0.9903 1464348 Maybridge4_002549 COc1ccc(cc1)C(=O)CSC2=NCCCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D20 compound treatment 29240.0 -12300.0 -0.71 37680.0 -7850.0 -0.59 -0.9254 -0.9958 3064384 Maybridge4_002550 CC(C)(C)C(=O)NC(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D21 compound treatment 18360.0 -23200.0 -1.35 20920.0 -24600.0 -1.86 -2.2682 -0.9872 3178949 Maybridge4_002551 O=C(Cc1cccc(Oc2ccccc2)c1)c3cccc(C#N)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D22 compound treatment 42240.0 665.0 0.04 50520.0 4990.0 0.38 0.2944 0.7752 3064385 Maybridge4_002552 CC1CCCC(C)N1c2nn(C)c(=O)[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D23 mock treatment 43680.0 2110.0 0.12 52320.0 6790.0 0.51 0.4497 0.8512 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 D24 mock treatment 45120.0 3550.0 0.21 49880.0 4350.0 0.33 0.3781 0.9742 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E01 compound treatment 42400.0 825.0 0.05 53120.0 7590.0 0.57 0.4401 0.7633 3064421 Maybridge4_002553 Cn1c(SCc2ccc(F)cc2)nnc1C3COc4ccccc4O3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E02 compound treatment 49280.0 7710.0 0.45 56760.0 11200.0 0.85 0.9168 0.9548 3064422 Maybridge4_002554 CCOC(=O)c1cncc(C#CCOC(=O)Nc2ccc(OC(F)(F)F)cc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E03 compound treatment 34040.0 -7540.0 -0.44 40480.0 -5050.0 -0.38 -0.5789 -0.9978 1569623 Maybridge4_002555 Clc1ccc(NC(=O)NCC2COc3ccccc3O2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E04 compound treatment 49040.0 7470.0 0.43 53440.0 7910.0 0.6 0.7293 0.9872 3064423 Maybridge4_002556 C/S(=N\S(=O)(=O)c1cccc2nsnc12)/c3ncc(Cl)cc3C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E05 compound treatment 40800.0 -775.0 -0.04 43960.0 -1570.0 -0.12 -0.1157 -0.9115 1912560 Maybridge4_002557 CNC(=O)N(c1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E06 compound treatment 37280.0 -4300.0 -0.25 44280.0 -1250.0 -0.09 -0.2428 -0.9121 1719037 Maybridge4_002558 Clc1ccc(cc1)C(=O)OCc2sccc2Oc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E07 compound treatment 40000.0 -1580.0 -0.09 45440.0 -88.8 -0.01 -0.0693 -0.7571 3064424 Maybridge4_002559 Clc1ccc(SC(=O)c2csc(n2)c3ccc4nonc4c3)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E08 compound treatment 36120.0 -5460.0 -0.32 45360.0 -169.0 -0.01 -0.2325 -0.7351 1379034 Maybridge4_002560 Cc1ccc(SC(=O)c2ccc(C#Cc3ccccc3)o2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E09 compound treatment 39680.0 -1900.0 -0.11 43600.0 -1930.0 -0.15 -0.1809 -0.9901 3178950 Maybridge4_002561 O=C1CC2Sc3ccccc3N=C2N1Cc4ccccn4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E10 compound treatment 31560.0 -10000.0 -0.58 36600.0 -8930.0 -0.68 -0.8882 -0.9971 3064426 Maybridge4_002562 CCOC(=O)c1c(Oc2ccc(OC)cc2)c3cccc(c3nc1SC)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E11 compound treatment 36000.0 -5580.0 -0.32 46640.0 1110.0 0.08 -0.1689 -0.5061 3178951 Maybridge4_002563 Cn1cc(/C(=N/O)/N)c(=O)n(Cc2ccccc2)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E12 compound treatment 37240.0 -4340.0 -0.25 39400.0 -6130.0 -0.46 -0.5056 -0.9585 3178952 Maybridge4_002564 COC(=O)C(Cc1csc2ccc(Cl)cc12)NC(=O)c3ccc(cc3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E13 compound treatment 29320.0 -12300.0 -0.71 36320.0 -9210.0 -0.7 -0.995 -1.0 1645379 Maybridge4_002565 CC(C)n1cc(c2nc(C)cs2)c(=O)n(Cc3ccccc3)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E14 compound treatment 34480.0 -7100.0 -0.41 39760.0 -5770.0 -0.44 -0.5994 -0.9995 3064427 Maybridge4_002566 O=C(OCC#Cc1ccc(C#N)cc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E15 compound treatment 18520.0 -23100.0 -1.34 23800.0 -21700.0 -1.64 -2.1075 -0.9947 3178953 Maybridge4_002567 COC(=O)c1scc2c(Oc3ccccc3C(F)(F)F)cc(nc12)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E16 compound treatment 30600.0 -11000.0 -0.64 38080.0 -7450.0 -0.56 -0.8483 -0.9982 3178954 Maybridge4_002568 CC(C)(C)c1cc2nc(cc(N3CCN(CC3)c4ccc(cn4)C(F)(F)F)n2n1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E17 compound treatment 16600.0 -25000.0 -1.45 19360.0 -26200.0 -1.98 -2.4238 -0.9881 3064428 Maybridge4_002569 Cc1ccc(SCc2nccn2Cc3ccc(Cl)cc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E18 compound treatment 38000.0 -3580.0 -0.21 43960.0 -1570.0 -0.12 -0.2304 -0.9651 3178955 Maybridge4_002570 Cn1c(Cc2nc(no2)c3cnccn3)nnc1SCc4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E19 compound treatment 35880.0 -5700.0 -0.33 43480.0 -2050.0 -0.16 -0.343 -0.9407 1530658 Maybridge4_002571 Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)N=S(=O)(C)c3ccc(C)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E20 compound treatment 39560.0 -2020.0 -0.12 42160.0 -3370.0 -0.25 -0.2629 -0.9373 1174825 Maybridge4_002572 Cn1c(S)nnc1CCN(Cc2ccco2)S(=O)(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E21 compound treatment 25400.0 -16200.0 -0.94 38440.0 -7090.0 -0.54 -1.0421 -0.965 1683285 Maybridge4_002573 COc1ccc(cc1)C(=O)CSC2=NCCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E22 compound treatment 22480.0 -19100.0 -1.11 21440.0 -24100.0 -1.82 -2.0716 -0.9713 1586313 Maybridge4_002574 COc1ccc(NC(=O)Nc2cc(F)cc(F)c2)cc1OC3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E23 mock treatment 41760.0 185.0 0.01 45520.0 -8.75 0.0 0.0071 0.6621 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 E24 mock treatment 43000.0 1430.0 0.08 47840.0 2310.0 0.17 0.1821 0.9413 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F01 compound treatment 48840.0 7270.0 0.42 56040.0 10500.0 0.8 0.8602 0.9557 1006297 Maybridge4_002575 Clc1ccc(CCc2ccc(Cl)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F02 compound treatment 16400.0 -25200.0 -1.46 18120.0 -27400.0 -2.07 -2.4984 -0.9851 3178956 Maybridge4_002576 Clc1ccccc1C(=O)NC(=O)Nc2ccc3C=CS(=O)(=O)c3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F03 compound treatment 41840.0 265.0 0.02 44720.0 -809.0 -0.06 -0.0324 -0.5138 1320469 Maybridge4_002577 O=C(Cc1ccc(CC(=O)c2ccccc2)cc1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F04 compound treatment 33720.0 -7860.0 -0.46 39360.0 -6170.0 -0.47 -0.652 -0.9999 1267104 Maybridge4_002578 Cc1c(CC(=O)Nc2ccc(Cl)cc2)sc3ccc(Cl)cc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F05 compound treatment 37080.0 -4500.0 -0.26 47560.0 2030.0 0.15 -0.0754 -0.2494 3064429 Maybridge4_002579 CCCn1c(=O)ccn(c2ccccc2C)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F06 compound treatment 9480.0 -32100.0 -1.86 13680.0 -31800.0 -2.41 -3.0195 -0.9918 1449737 Maybridge4_002580 O=C(CSC1=NCCc2ccccc12)c3ccc(cc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F07 compound treatment 42600.0 1030.0 0.06 46760.0 1230.0 0.09 0.1079 0.9763 3064430 Maybridge4_002581 O=C(CNC(=O)OCc1ccccc1)ON2C(=O)CCC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F08 compound treatment 11600.0 -30000.0 -1.74 17280.0 -28200.0 -2.14 -2.74 -0.9947 1291828 Maybridge4_002582 Cc1c(sc2ccc(Cl)cc12)c3cc(NC(=O)c4ccccc4)[nH]n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F09 compound treatment 35840.0 -5740.0 -0.33 43240.0 -2290.0 -0.17 -0.3575 -0.9539 3064431 Maybridge4_002583 CC(=O)OC1CCN(CC1)c2cc(nc3cc(Cl)cc(Cl)c23)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F10 compound treatment 31080.0 -10500.0 -0.61 32480.0 -13000.0 -0.99 -1.1284 -0.9728 3178957 Maybridge4_002584 CNC(=S)c1sc2ccccc2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F11 compound treatment 31640.0 -9940.0 -0.58 39840.0 -5690.0 -0.43 -0.7115 -0.9898 1269577 Maybridge4_002585 O=C(NCc1ccc(s1)S(=O)(=O)NCc2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F12 compound treatment 33040.0 -8540.0 -0.49 40400.0 -5130.0 -0.39 -0.6242 -0.9928 3064432 Maybridge4_002586 FC(F)(F)COc1ccc(c(OCC(F)(F)F)c1C#N)S(=O)(=O)N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F13 compound treatment 37040.0 -4540.0 -0.26 38960.0 -6570.0 -0.5 -0.5374 -0.9556 1508849 Maybridge4_002587 CCC(C)c1ccccc1NC(=O)c2cc3cc(CC)ccc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F14 compound treatment 28480.0 -13100.0 -0.76 37720.0 -7810.0 -0.59 -0.9544 -0.9924 3064434 Maybridge4_002588 FC(F)(F)COc1ccc(SCC=C)c(OCC(F)(F)F)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F15 compound treatment 26960.0 -14600.0 -0.85 30360.0 -15200.0 -1.15 -1.4106 -0.9888 1212532 Maybridge4_002589 Cc1cccc(NC(=O)NC(=O)c2ccc(s2)C(C)(C)C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F16 compound treatment 31840.0 -9740.0 -0.56 34280.0 -11200.0 -0.85 -1.0009 -0.98 3064435 Maybridge4_002590 C(N1CCC(=N1)/C=C/c2ccco2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F17 compound treatment 35880.0 -5700.0 -0.33 44720.0 -809.0 -0.06 -0.2766 -0.8242 1289651 Maybridge4_002591 CC(C)N(C(C)C)C(=O)NC(=O)c1ccc(F)cc1F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F18 compound treatment 41840.0 265.0 0.02 40640.0 -4890.0 -0.37 -0.2508 -0.6772 3064458 Maybridge4_002592 NN/C(=N\S(=O)(=O)c1ccccc1)/Nc2cccc(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F19 compound treatment 38480.0 -3100.0 -0.18 43560.0 -1970.0 -0.15 -0.2322 -0.9958 3064459 Maybridge4_002593 FC(F)(F)c1cccc(c1)n2c(n[nH]c2=S)c3ccncc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F20 compound treatment 37560.0 -4020.0 -0.23 37920.0 -7610.0 -0.58 -0.5717 -0.9205 3064460 Maybridge4_002594 NNC(=S)c1cc(Cl)cc(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F21 compound treatment 36480.0 -5100.0 -0.3 40440.0 -5090.0 -0.39 -0.4811 -0.9914 3064461 Maybridge4_002595 NC(=O)c1ccc(CC(=O)c2ccc(Cl)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F22 compound treatment 43400.0 1830.0 0.11 45000.0 -529.0 -0.04 0.0465 0.411 3064462 Maybridge4_002596 C1CN=C(S1)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F23 mock treatment 40920.0 -655.0 -0.04 46000.0 471.0 0.04 -0.0016 -0.0309 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 F24 mock treatment 42360.0 785.0 0.05 50440.0 4910.0 0.37 0.295 0.7877 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G01 compound treatment 40680.0 -895.0 -0.05 43240.0 -2290.0 -0.17 -0.1592 -0.8802 3064463 Maybridge4_002597 Cn1c(SCC(=O)c2ccccc2)nnc1C3COc4ccccc4O3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G02 compound treatment 34640.0 -6940.0 -0.4 38360.0 -7170.0 -0.54 -0.6678 -0.9891 3064464 Maybridge4_002598 COc1cc(nc2ccc(C)c(NC(=O)c3ccc(Cl)cc3)c12)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G03 compound treatment 36720.0 -4860.0 -0.28 36040.0 -9490.0 -0.72 -0.7068 -0.9163 1291018 Maybridge4_002599 Cc1ccc(NC(=S)NCC2COc3ccccc3O2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G04 compound treatment 30040.0 -11500.0 -0.67 35360.0 -10200.0 -0.77 -1.0168 -0.9975 3064465 Maybridge4_002600 Cc1c(noc1C(=O)CN=S(=O)(C)c2ccc(cn2)C(F)(F)F)c3c(Cl)cccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G05 compound treatment 40200.0 -1380.0 -0.08 40240.0 -5290.0 -0.4 -0.3394 -0.8315 3178958 Maybridge4_002601 COc1cccn(Cc2nnc(S)n2C)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G06 compound treatment 33400.0 -8180.0 -0.47 40520.0 -5010.0 -0.38 -0.603 -0.9939 1395477 Maybridge4_002602 Clc1ccccc1C(=O)N2CCC(CC2)n3cccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G07 compound treatment 37160.0 -4420.0 -0.26 46080.0 551.0 0.04 -0.1514 -0.584 3064466 Maybridge4_002603 Clc1ccc(cc1)C(=O)CSc2nc3CSCc3c(=O)[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G08 compound treatment 32480.0 -9100.0 -0.53 38080.0 -7450.0 -0.56 -0.7713 -0.9994 1133834 Maybridge4_002604 O=c1[nH]c(=O)n(nc1C#N)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G09 compound treatment 37880.0 -3700.0 -0.21 41240.0 -4290.0 -0.32 -0.3809 -0.9796 3064468 Maybridge4_002605 CCOC(=O)c1nnc2c(Br)c(C)nn2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G10 compound treatment 26920.0 -14700.0 -0.85 34520.0 -11000.0 -0.83 -1.1896 -1.0 3178959 Maybridge4_002606 CSc1nn(cc1C(=O)Nc2cccc(c2)C(F)(F)F)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G11 compound treatment 32920.0 -8660.0 -0.5 41120.0 -4410.0 -0.33 -0.5906 -0.9804 1533729 Maybridge4_002607 CC(C)n1cc(c2noc(n2)c3ccccc3Cl)c(=O)n(Cc4ccccc4)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G12 compound treatment 28360.0 -13200.0 -0.77 40400.0 -5130.0 -0.39 -0.8159 -0.9504 1333749 Maybridge4_002608 CSc1nc2c(Cl)cccc2c3n(C)n(Cc4ccc(Cl)cc4)c(=O)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G13 compound treatment 29920.0 -11700.0 -0.68 37960.0 -7570.0 -0.57 -0.8826 -0.9967 1217547 Maybridge4_002609 CC(C)n1cc(c2nc(cs2)C(C)(C)C)c(=O)n(Cc3ccccc3)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G14 compound treatment 35000.0 -6580.0 -0.38 40360.0 -5170.0 -0.39 -0.546 -0.9999 1707847 Maybridge4_002610 CCCn1c(=O)cc(N)n(c2ccc(Cl)cc2)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G15 compound treatment 34520.0 -7060.0 -0.41 44320.0 -1210.0 -0.09 -0.3537 -0.8445 1123385 Maybridge4_002611 CCOC(=O)c1cn(Cc2cccc(Cl)c2)c3cc(C)nn3c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G16 compound treatment 32680.0 -8900.0 -0.52 41880.0 -3650.0 -0.28 -0.5597 -0.9573 3064470 Maybridge4_002612 CCCn1c(=O)cc(N)n(c2ccc(OC(F)(F)F)cc2)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G17 compound treatment 13120.0 -28500.0 -1.65 15400.0 -30100.0 -2.28 -2.7784 -0.9873 3178960 Maybridge4_002613 CC(C)(C)c1cc2nc(cc(Sc3ccccc3)n2n1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G18 compound treatment 34080.0 -7500.0 -0.43 41040.0 -4490.0 -0.34 -0.5473 -0.9926 3064471 Maybridge4_002614 Cn1c(Cc2nc(no2)c3cnccn3)nnc1SCC(=O)Nc4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G19 compound treatment 34080.0 -7500.0 -0.43 45320.0 -209.0 -0.02 -0.3182 -0.7324 1167659 Maybridge4_002615 Cn1c(=O)c(cn(c2ccccc2)c1=O)c3noc(n3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G20 compound treatment 20160.0 -21400.0 -1.24 28000.0 -17500.0 -1.33 -1.8155 -0.9994 1420377 Maybridge4_002616 Clc1ccc(NC(=O)CCN(Cc2ccco2)S(=O)(=O)c3ccc(Cl)cc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G21 compound treatment 29840.0 -11700.0 -0.68 33640.0 -11900.0 -0.9 -1.1171 -0.9904 3064472 Maybridge4_002617 FC(F)(F)Oc1ccc(NC(=O)N2CCN(CC2)C(c3ccccc3)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G22 compound treatment 34160.0 -7420.0 -0.43 41560.0 -3970.0 -0.3 -0.5162 -0.9847 1413855 Maybridge4_002618 O=C(N1CCN(CC1)C(c2ccccc2)c3ccccc3)c4ccc5nonc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G23 mock treatment 39360.0 -2220.0 -0.13 45120.0 -409.0 -0.03 -0.1126 -0.8531 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 G24 mock treatment 40400.0 -1180.0 -0.07 47520.0 1990.0 0.15 0.0584 0.3534 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H01 compound treatment 42560.0 985.0 0.06 50840.0 5310.0 0.4 0.3246 0.7995 3064474 Maybridge4_002619 Cc1ccccc1NC(=O)NC(=O)CC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H02 compound treatment 40360.0 -1220.0 -0.07 44520.0 -1010.0 -0.08 -0.1038 -0.9992 1680806 Maybridge4_002620 OC(=O)Cc1csc2ccc(Cl)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H03 compound treatment 30800.0 -10800.0 -0.62 37320.0 -8210.0 -0.62 -0.8808 -1.0 3064475 Maybridge4_002621 COc1ccccc1CCn2cc(C#N)c(=O)[nH]c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H04 compound treatment 38200.0 -3380.0 -0.2 41880.0 -3650.0 -0.28 -0.3336 -0.9857 3179054 Maybridge4_002622 Cc1cccc(NC(=S)N2CCOC2c3ccsc3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H05 compound treatment 35600.0 -5980.0 -0.35 41160.0 -4370.0 -0.33 -0.4786 -0.9997 1623471 Maybridge4_002623 CCCn1c(=O)c(C#N)cn(C2CC2)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H06 compound treatment 29400.0 -12200.0 -0.71 35680.0 -9850.0 -0.75 -1.0259 -0.9996 3179055 Maybridge4_002624 Cc1c(sc2ccc(Cl)cc12)c3ccnn3S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H07 compound treatment 30600.0 -11000.0 -0.64 44000.0 -1530.0 -0.12 -0.5314 -0.8223 3179056 Maybridge4_002625 COc1ccc(Cn2c(=O)n(c3cc(ccc3C)S(=O)C)c4nc[nH]c4c2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H08 compound treatment 35560.0 -6020.0 -0.35 39120.0 -6410.0 -0.49 -0.5894 -0.9868 3064477 Maybridge4_002626 CC(C)c1ccc(/N=C/c2sc3ccccc3c2C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H09 compound treatment 19080.0 -22500.0 -1.3 32840.0 -12700.0 -0.96 -1.6007 -0.9887 3179057 Maybridge4_002627 CCOC(=O)c1ccc2nc(cc(N3CCN(CC3)c4ccccc4)c2c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H10 compound treatment 28240.0 -13300.0 -0.77 32640.0 -12900.0 -0.98 -1.2362 -0.9933 3064478 Maybridge4_002628 Cc1c(/C=N/O)sc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H11 compound treatment 28480.0 -13100.0 -0.76 36280.0 -9250.0 -0.7 -1.0315 -0.9992 3064510 Maybridge4_002629 COc1ccc(cc1)c2ccnc(SCc3ccc(Cl)cc3Cl)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H12 compound treatment 32160.0 -9420.0 -0.55 35840.0 -9690.0 -0.73 -0.9043 -0.9894 1135828 Maybridge4_002630 OC(=O)CC(NC(=O)Nc1ccccc1)c2ccsc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H13 compound treatment 19520.0 -22100.0 -1.28 28240.0 -17300.0 -1.31 -1.8289 -0.9999 1625372 Maybridge4_002631 Clc1ccc2c(ccnc2c1)N3CCN(CC3)C(=O)C4CCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H14 compound treatment 31880.0 -9700.0 -0.56 38600.0 -6930.0 -0.52 -0.768 -0.9994 3064512 Maybridge4_002632 COc1ccc(NS(=O)(=O)c2ccc(OCC(F)(F)F)c(C#N)c2OCC(F)(F)F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H15 compound treatment 29600.0 -12000.0 -0.69 36120.0 -9410.0 -0.71 -0.9942 -0.9999 3064513 Maybridge4_002633 CCOC(=O)c1sc(Nc2ccccc2C(F)(F)F)c(C(=O)OCC)c1N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H16 compound treatment 26440.0 -15100.0 -0.88 35880.0 -9650.0 -0.73 -1.1365 -0.9959 3064514 Maybridge4_002634 Clc1cccc(N/C(=N\S(=O)(=O)c2ccccc2)/NCCc3ccccn3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H17 compound treatment 32680.0 -8900.0 -0.52 38320.0 -7210.0 -0.55 -0.7503 -0.9996 3064515 Maybridge4_002635 CCOC(=O)NC(=S)Nc1cccc(C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H18 compound treatment 38440.0 -3140.0 -0.18 39440.0 -6090.0 -0.46 -0.4543 -0.9171 3179058 Maybridge4_002636 CCOC(=O)NC(=S)N1CCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H19 compound treatment 31000.0 -10600.0 -0.61 38440.0 -7090.0 -0.54 -0.8127 -0.9978 3179059 Maybridge4_002637 COc1ccc(CSC2=NCN(CN2)C3CC(C)CC(C)(C)C3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H20 compound treatment 30640.0 -10900.0 -0.63 42800.0 -2730.0 -0.21 -0.594 -0.8915 1226235 Maybridge4_002638 S=C(NCc1ccccc1)NCc2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H21 compound treatment 30520.0 -11100.0 -0.64 34120.0 -11400.0 -0.86 -1.0635 -0.9892 3179060 Maybridge4_002639 O=C(Cc1ccc(Oc2ccccc2)cc1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H22 compound treatment 36920.0 -4660.0 -0.27 36560.0 -8970.0 -0.68 -0.6708 -0.9182 3064516 Maybridge4_002640 CCOC(=S)Nc1cccc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H23 mock treatment 37880.0 -3700.0 -0.21 41720.0 -3810.0 -0.29 -0.3552 -0.9893 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 H24 mock treatment 36040.0 -5540.0 -0.32 46880.0 1350.0 0.1 -0.1544 -0.4588 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I01 compound treatment 42280.0 705.0 0.04 47600.0 2070.0 0.16 0.1397 0.8625 1349293 Maybridge4_002641 COC(=O)c1ccc-2c(c1)N(C)S(=O)(=O)c3cnc(SC)nc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I02 compound treatment 42200.0 625.0 0.04 41400.0 -4130.0 -0.31 -0.1954 -0.621 3064517 Maybridge4_002642 NNC(=O)c1cncc(C#Cc2ccccc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I03 compound treatment 41720.0 145.0 0.01 42280.0 -3250.0 -0.25 -0.1679 -0.6826 1297264 Maybridge4_002643 Clc1ccc(cc1)C(=O)NC(=S)NCC2COc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I04 compound treatment 36000.0 -5580.0 -0.32 44960.0 -569.0 -0.04 -0.2588 -0.7943 1443440 Maybridge4_002644 COC(=O)c1csc(c1OC)S(=O)(=O)N=S(=O)(C)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I05 compound treatment 32040.0 -9540.0 -0.55 47240.0 1710.0 0.13 -0.299 -0.527 3179061 Maybridge4_002645 COc1ccc2nc([nH]c2c1)S(=O)Cc3ncc(C)c(OC)c3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I06 compound treatment 33240.0 -8340.0 -0.48 38160.0 -7370.0 -0.56 -0.7359 -0.9974 1207614 Maybridge4_002646 Clc1ccc(cc1)S(=O)(=O)N2CCC(CC2)n3cccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I07 compound treatment 1440.0 -40100.0 -2.33 2280.0 -43200.0 -3.27 -3.9591 -0.986 1176328 Maybridge4_002647 Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCC(=O)c4ccc(Cl)cc4Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I08 compound treatment 1680.0 -39900.0 -2.31 4080.0 -41400.0 -3.14 -3.8529 -0.9887 1698489 Maybridge4_002648 Clc1ccc(Cn2c(=O)c(C#N)nn(c3ccccc3)c2=O)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I09 compound treatment 33560.0 -8020.0 -0.46 46480.0 951.0 0.07 -0.2774 -0.5904 1223405 Maybridge4_002649 CCOC(=O)NC(=O)c1cn(CCc2ccncc2)c(=O)[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I10 compound treatment 26480.0 -15100.0 -0.87 35640.0 -9890.0 -0.75 -1.1477 -0.997 1257420 Maybridge4_002650 CSc1nn(cc1C(=O)N2CCCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I11 compound treatment 31560.0 -10000.0 -0.58 38400.0 -7130.0 -0.54 -0.7919 -0.9993 3064519 Maybridge4_002651 CC(C)n1cc(/C(=N/O)/N)c(=O)n(Cc2ccccc2)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I12 compound treatment 30400.0 -11200.0 -0.65 38280.0 -7250.0 -0.55 -0.8458 -0.9966 1544891 Maybridge4_002652 OC(=O)C1CNC(=O)N1C(=O)OCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I13 compound treatment 21600.0 -20000.0 -1.16 26520.0 -19000.0 -1.44 -1.8358 -0.9942 1689579 Maybridge4_002653 CCOC(=O)c1csc(n1)c2cn(C(C)C)c(=O)n(Cc3ccccc3)c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I14 compound treatment 28960.0 -12600.0 -0.73 37880.0 -7650.0 -0.58 -0.9262 -0.9933 3064520 Maybridge4_002654 Cn1c(CSCC(=O)Nc2ccccc2)nnc1SCc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I15 compound treatment 22880.0 -18700.0 -1.08 32280.0 -13200.0 -1.0 -1.475 -0.9993 3179062 Maybridge4_002655 Cc1[nH]c2ccccc2c1SCc3nnc(SCc4ccc(Cl)cc4)n3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I16 compound treatment 29520.0 -12100.0 -0.7 37000.0 -8530.0 -0.65 -0.9504 -0.9992 3064521 Maybridge4_002656 Cn1c(CSCC(=O)Nc2ccccc2)nnc1SCC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I17 compound treatment 20600.0 -21000.0 -1.22 27760.0 -17800.0 -1.34 -1.8104 -0.9987 3179063 Maybridge4_002657 COc1ccc(Oc2cc(nc3cc(nn23)C(C)(C)C)C(F)(F)F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I18 compound treatment 33800.0 -7780.0 -0.45 32320.0 -13200.0 -1.0 -1.0255 -0.9352 3179064 Maybridge4_002658 CSc1cccc(NC(=O)N(Cc2ccccc2)C(=O)CC#N)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I19 compound treatment 33080.0 -8500.0 -0.49 36320.0 -9210.0 -0.7 -0.8409 -0.9855 1399847 Maybridge4_002659 O=S1(=O)CC(N2CCCC2)c3ccccc31 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I20 compound treatment 30040.0 -11500.0 -0.67 36080.0 -9450.0 -0.72 -0.9783 -0.9994 3179065 Maybridge4_002660 FC(F)(F)c1cc(N2CCC(CC2)n3cccc3)c4ccccc4n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I21 compound treatment 39400.0 -2180.0 -0.13 40360.0 -5170.0 -0.39 -0.3658 -0.8898 3064522 Maybridge4_002661 O=C(OCc1ccc(C#Cc2ccccc2)s1)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I22 compound treatment 37280.0 -4300.0 -0.25 37040.0 -8490.0 -0.64 -0.6303 -0.9147 1065782 Maybridge4_002662 O=C(NCc1ccccc1)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I23 mock treatment 42120.0 545.0 0.03 47280.0 1750.0 0.13 0.1161 0.8517 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 I24 mock treatment 40400.0 -1180.0 -0.07 45280.0 -249.0 -0.02 -0.0615 -0.87 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J01 compound treatment 43640.0 2070.0 0.12 41600.0 -3930.0 -0.3 -0.1257 -0.3921 3064524 Maybridge4_002663 Cn1c(SCc2cc(F)cc(F)c2)nnc1c3ccc4nonc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J02 compound treatment 33080.0 -8500.0 -0.49 40240.0 -5290.0 -0.4 -0.6311 -0.9947 3179066 Maybridge4_002664 Clc1ccc2scc(CC(=O)OCc3ccccc3)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J03 compound treatment 29160.0 -12400.0 -0.72 37520.0 -8010.0 -0.61 -0.9373 -0.9964 3064525 Maybridge4_002665 FC(F)(F)c1cc(N2CCCCC2)c3cccc(Cl)c3n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J04 compound treatment 30440.0 -11100.0 -0.65 37280.0 -8250.0 -0.62 -0.8977 -0.9999 3179067 Maybridge4_002666 NC(=S)Cc1c(Cl)sc2ccc(Cl)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J05 compound treatment 34640.0 -6940.0 -0.4 41080.0 -4450.0 -0.34 -0.5222 -0.9961 1230774 Maybridge4_002667 O=c1c(C#N)cn(C2CC2)c(=O)n1Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J06 compound treatment 24880.0 -16700.0 -0.97 32880.0 -12600.0 -0.96 -1.361 -1.0 3064526 Maybridge4_002668 Cc1c(sc2ccc(Cl)cc12)c3ccnc(SCC=C)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J07 compound treatment 35960.0 -5620.0 -0.33 41880.0 -3650.0 -0.28 -0.4253 -0.9967 1249532 Maybridge4_002669 Cc1cc(NC(=O)c2ccc3nonc3c2)on1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J08 compound treatment 19960.0 -21600.0 -1.25 24440.0 -21100.0 -1.6 -2.0143 -0.9928 1640712 Maybridge4_002670 CN1C(=O)CC(Sc2ccccc12)c3ccsc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J09 compound treatment 21640.0 -19900.0 -1.15 32560.0 -13000.0 -0.98 -1.5108 -0.9967 3064554 Maybridge4_002671 Cc1ccc2c(cc(nc2c1)C(F)(F)F)N3CC4CCC(CC4)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J10 compound treatment 33960.0 -7620.0 -0.44 38280.0 -7250.0 -0.55 -0.7 -0.9942 3064555 Maybridge4_002672 Fc1ccc(NC2=NNC(=O)C2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J11 compound treatment 30880.0 -10700.0 -0.62 37280.0 -8250.0 -0.62 -0.8797 -1.0 3064556 Maybridge4_002673 COc1ccc(cc1)c2ccnc(SCC(=O)N3CCOCC3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J12 compound treatment 23520.0 -18100.0 -1.05 28960.0 -16600.0 -1.25 -1.6265 -0.9959 1655959 Maybridge4_002674 CCCS(=O)(=O)c1ccc(NC(=O)Nc2ccc(Cl)cc2Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J13 compound treatment 12520.0 -29100.0 -1.68 18760.0 -26800.0 -2.03 -2.6231 -0.9958 1535225 Maybridge4_002675 CC(C)N(C(C)C)C(=O)N1CCN(CC1)c2ccnc3cc(Cl)ccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J14 compound treatment 27120.0 -14500.0 -0.84 37440.0 -8090.0 -0.61 -1.0251 -0.9881 3064558 Maybridge4_002676 FC(F)(F)COc1ccc(Br)c(OCC(F)(F)F)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J15 compound treatment 13040.0 -28500.0 -1.65 17800.0 -27700.0 -2.1 -2.6532 -0.993 3064559 Maybridge4_002677 COC(=O)c1ccccc1SC(=O)c2ccc(Cl)c(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J16 compound treatment 26400.0 -15200.0 -0.88 39840.0 -5690.0 -0.43 -0.9262 -0.9461 1497304 Maybridge4_002678 Clc1ccc(NC(=S)NS(=O)(=O)c2ccccc2)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J17 compound treatment 30200.0 -11400.0 -0.66 38040.0 -7490.0 -0.57 -0.8668 -0.9972 1102994 Maybridge4_002679 CCOC(=O)NC(=S)c1cccn1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J18 compound treatment 30960.0 -10600.0 -0.62 35120.0 -10400.0 -0.79 -0.992 -0.9925 1203607 Maybridge4_002680 COc1ccc(OC)c(c1)S(=O)(=O)N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J19 compound treatment 31640.0 -9940.0 -0.58 37600.0 -7930.0 -0.6 -0.8314 -0.9998 3064560 Maybridge4_002681 S=C1NCN(Cc2ccncc2)CN1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J20 compound treatment 19160.0 -22400.0 -1.3 24880.0 -20600.0 -1.56 -2.0235 -0.9958 3179068 Maybridge4_002682 Cc1cc(Br)c(NC(=S)NC(=O)C(C)(C)C)c(Br)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J21 compound treatment 32720.0 -8860.0 -0.51 37000.0 -8530.0 -0.65 -0.8193 -0.9935 3064561 Maybridge4_002683 COC(=O)c1ccc2[nH]cnc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J22 compound treatment 38560.0 -3020.0 -0.17 41880.0 -3650.0 -0.28 -0.3188 -0.9756 3179069 Maybridge4_002684 O=c1[nH]nc([nH]1)N2CCSCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J23 mock treatment 37400.0 -4180.0 -0.24 42440.0 -3090.0 -0.23 -0.3364 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 J24 mock treatment 43160.0 1590.0 0.09 36960.0 -8570.0 -0.65 -0.3937 -0.601 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K01 compound treatment 37440.0 -4140.0 -0.24 37920.0 -7610.0 -0.58 -0.5767 -0.9245 3064562 Maybridge4_002685 COC(=O)c1ccc2OCCc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K02 compound treatment 14040.0 -27500.0 -1.6 12640.0 -32900.0 -2.49 -2.8884 -0.9769 3179151 Maybridge4_002686 CCOC(=O)c1cncc(C#CCOC(=O)c2c(C)onc2c3ccccc3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K03 compound treatment 6600.0 -35000.0 -2.03 7560.0 -38000.0 -2.87 -3.4651 -0.9854 1273322 Maybridge4_002687 CCOC(=O)Cc1nn(Cc2nc(cs2)c3ccccc3)c(=O)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K04 compound treatment 13800.0 -27800.0 -1.61 21280.0 -24200.0 -1.84 -2.4358 -0.9978 3179152 Maybridge4_002688 CN(CCOC(=O)c1ccccc1)c2cc(nc3ccccc23)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K05 compound treatment 26120.0 -15500.0 -0.9 31800.0 -13700.0 -1.04 -1.368 -0.9973 3179153 Maybridge4_002689 COc1cccn(Cc2nnc(SCC(=O)c3ccccc3)o2)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K06 compound treatment 21880.0 -19700.0 -1.14 26720.0 -18800.0 -1.42 -1.8136 -0.994 1551980 Maybridge4_002690 Clc1cc(Cl)cc(NC(=O)N2CCC(CC2)n3cccc3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K07 compound treatment 12560.0 -29000.0 -1.68 22760.0 -22800.0 -1.72 -2.4074 -0.9999 3179154 Maybridge4_002691 CN(C)c1cc(nc2cc(nn12)C(C)(C)C)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K08 compound treatment 27760.0 -13800.0 -0.8 38000.0 -7530.0 -0.57 -0.9689 -0.9861 3064563 Maybridge4_002692 CCCn1c(=O)c(nn(c2ccccc2)c1=O)/C(=N/O)/N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K09 compound treatment 16040.0 -25500.0 -1.48 24520.0 -21000.0 -1.59 -2.1706 -0.9993 1707363 Maybridge4_002693 Cc1ncn2cc([nH]c(=O)c12)c3ccc(Cl)cc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K10 compound treatment 23400.0 -18200.0 -1.05 28120.0 -17400.0 -1.32 -1.6764 -0.9938 3179155 Maybridge4_002694 COC(=O)c1c(C)[nH]c(C)c1/C=C(\C#N)/S(=O)(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K11 compound treatment 26480.0 -15100.0 -0.87 34320.0 -11200.0 -0.85 -1.2184 -0.9999 1478501 Maybridge4_002695 CC(C)n1cc(c2noc(n2)c3cccs3)c(=O)n(Cc4ccccc4)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K12 compound treatment 5040.0 -36500.0 -2.12 9040.0 -36500.0 -2.76 -3.4498 -0.9914 3179156 Maybridge4_002696 O=S(=O)(c1ccccc1)n2ccc(n2)c3ccc(C#Cc4ccccc4)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K13 compound treatment 24600.0 -17000.0 -0.98 33240.0 -12300.0 -0.93 -1.3532 -0.9996 1572994 Maybridge4_002697 CC(C)n1cc(c2nc(cs2)C(=O)NN)c(=O)n(Cc3ccccc3)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K14 compound treatment 22840.0 -18700.0 -1.09 31560.0 -14000.0 -1.06 -1.5152 -0.9999 1626520 Maybridge4_002698 O=C(CSc1nc2ccccc2o1)N3CCC(CC3)n4cccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K15 compound treatment 23320.0 -18300.0 -1.06 29080.0 -16400.0 -1.25 -1.6283 -0.9967 3179157 Maybridge4_002699 COc1cc(nc2ccc(C#CCOC(=O)c3ccccc3)cc12)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K16 compound treatment 24600.0 -17000.0 -0.98 35720.0 -9810.0 -0.74 -1.2204 -0.9904 3064565 Maybridge4_002700 CCOC(=O)N1CCC(CC1)N/C=C(\C#N)/S(=O)(=O)c2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K17 compound treatment 31000.0 -10600.0 -0.61 30760.0 -14800.0 -1.12 -1.2237 -0.9599 3179158 Maybridge4_002701 Cc1ccc(cc1)S(=O)(=O)CCN2CCC(CC2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K18 compound treatment 880.0 -40700.0 -2.36 1800.0 -43700.0 -3.31 -4.0077 -0.9862 3064567 Maybridge4_002702 CSc1scc(NC(=O)c2ccc(Cl)cc2)c1S(=O)(=O)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K19 compound treatment 25840.0 -15700.0 -0.91 28360.0 -17200.0 -1.3 -1.5636 -0.985 3179159 Maybridge4_002703 O=S(=O)(/C(=C/N1CCN(CC1)C(c2ccccc2)c3ccccc3)/C#N)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K20 compound treatment 26000.0 -15600.0 -0.9 29080.0 -16400.0 -1.25 -1.5185 -0.9875 3064568 Maybridge4_002704 COC(=O)c1scc2c(cc(nc12)C(F)(F)F)N3CCC(CC3)n4cccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K21 compound treatment 28400.0 -13200.0 -0.76 31120.0 -14400.0 -1.09 -1.311 -0.9848 3179160 Maybridge4_002705 CCOC(=O)C1CCN(CC1)/C=C(\C#N)/S(=O)(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K22 compound treatment 1200.0 -40400.0 -2.34 840.0 -44700.0 -3.38 -4.046 -0.9838 1717162 Maybridge4_002706 CCCS(=O)(=O)c1cnc(nc1N)C2COc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K23 mock treatment 33560.0 -8020.0 -0.46 35280.0 -10200.0 -0.78 -0.8769 -0.9699 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 K24 mock treatment 34480.0 -7100.0 -0.41 39640.0 -5890.0 -0.45 -0.6059 -0.9992 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L01 compound treatment 39520.0 -2060.0 -0.12 45000.0 -529.0 -0.04 -0.1125 -0.8956 1068568 Maybridge4_002707 CCOC(=O)c1c(C)oc(=O)c(Br)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L02 compound treatment 30320.0 -11300.0 -0.65 36960.0 -8570.0 -0.65 -0.9197 -1.0 3064569 Maybridge4_002708 Clc1sc2ccc(Cl)cc2c1CC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L03 compound treatment 24640.0 -16900.0 -0.98 30680.0 -14800.0 -1.12 -1.4886 -0.9977 1726018 Maybridge4_002709 Clc1ccc(cc1)S(=O)(=O)CCN2CCN(CC2)C(c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L04 compound treatment 26680.0 -14900.0 -0.86 29160.0 -16400.0 -1.24 -1.4863 -0.9844 3064570 Maybridge4_002710 CCOC(=O)c1csc(Cc2c(Cl)sc3ccc(Cl)cc23)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L05 compound treatment 31040.0 -10500.0 -0.61 39560.0 -5970.0 -0.45 -0.7511 -0.989 3179161 Maybridge4_002711 Fc1ccc(NC(=O)NC(=O)CC#N)c(F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L06 compound treatment 31480.0 -10100.0 -0.58 41400.0 -4130.0 -0.31 -0.6346 -0.9569 1493566 Maybridge4_002712 O=C(SC1=NCCc2ccccc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L07 compound treatment 35520.0 -6060.0 -0.35 38520.0 -7010.0 -0.53 -0.6232 -0.9798 3064593 Maybridge4_002713 OC1(CC(=NN1)c2nccs2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L08 compound treatment 30800.0 -10800.0 -0.62 32920.0 -12600.0 -0.95 -1.1163 -0.9788 3064595 Maybridge4_002714 Cc1c(/C=C/C(=O)Oc2ccc(C#N)cc2)sc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L09 compound treatment 24560.0 -17000.0 -0.99 29240.0 -16300.0 -1.23 -1.5689 -0.9939 3064596 Maybridge4_002715 CCOC(=O)C1CCN(CC1)c2cc(nc3ccc(C)cc23)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L10 compound treatment 32840.0 -8740.0 -0.51 39280.0 -6250.0 -0.47 -0.6923 -0.9994 3064597 Maybridge4_002716 CC(C)c1ccc(NC2=NNC(=O)C2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L11 compound treatment 30400.0 -11200.0 -0.65 36880.0 -8650.0 -0.65 -0.9207 -1.0 3482130 Maybridge4_002717 CC(C)(C)OC(=O)Nc1ncnc2n(cnc12)C3OC(CO)C4OC(C)(C)OC34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L12 compound treatment 30480.0 -11100.0 -0.64 35960.0 -9570.0 -0.72 -0.9667 -0.9982 3064598 Maybridge4_002718 Cc1n[nH]c(C)c1Sc2nccc(n2)c3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L13 compound treatment 32320.0 -9260.0 -0.54 37560.0 -7970.0 -0.6 -0.8057 -0.9983 1572567 Maybridge4_002719 O=C(NCc1ccc(s1)S(=O)(=O)NCCN2CCOCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L14 compound treatment 16360.0 -25200.0 -1.46 20880.0 -24600.0 -1.87 -2.3523 -0.9927 3064599 Maybridge4_002720 NC(=O)c1csc(n1)c2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L15 compound treatment 37040.0 -4540.0 -0.26 40560.0 -4970.0 -0.38 -0.4517 -0.9846 3064600 Maybridge4_002721 Clc1ccc(cc1)c2nnc(o2)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L16 compound treatment 31600.0 -9980.0 -0.58 35920.0 -9610.0 -0.73 -0.923 -0.9935 3179162 Maybridge4_002722 CN(C)c1ccc(cc1)C2OCCN2C(=S)Nc3ccccc3F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L17 compound treatment 40920.0 -655.0 -0.04 43440.0 -2090.0 -0.16 -0.1386 -0.8526 3064601 Maybridge4_002723 Cc1ccc(cc1)C(=O)CSC2=NCCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L18 compound treatment 31760.0 -9820.0 -0.57 36840.0 -8690.0 -0.66 -0.8672 -0.9974 3179163 Maybridge4_002724 CC(C)CNC(=S)N1CCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L19 compound treatment 30280.0 -11300.0 -0.65 34280.0 -11200.0 -0.85 -1.0648 -0.9915 1286430 Maybridge4_002725 S=C1NCN(CN1)C(Cc2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L20 compound treatment 27840.0 -13700.0 -0.8 34680.0 -10800.0 -0.82 -1.1434 -0.9999 3064602 Maybridge4_002726 CCOC(=O)NC(=S)Nc1ccc(cc1)N2CC(C)OC(C)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L21 compound treatment 31480.0 -10100.0 -0.58 33560.0 -12000.0 -0.91 -1.0542 -0.9776 3179164 Maybridge4_002727 NNC(=O)C1CCC(CC1)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L22 compound treatment 29600.0 -12000.0 -0.69 30280.0 -15200.0 -1.15 -1.3068 -0.9703 1090059 Maybridge4_002728 CCOC(=O)NC(=S)c1ccc[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L23 mock treatment 33640.0 -7940.0 -0.46 39240.0 -6290.0 -0.48 -0.6617 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 L24 mock treatment 39680.0 -1900.0 -0.11 34600.0 -10900.0 -0.83 -0.6626 -0.794 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M01 compound treatment 39520.0 -2060.0 -0.12 46160.0 631.0 0.05 -0.0504 -0.3929 3179165 Maybridge4_002729 O=S(=O)(Cc1ccc2nonc2c1)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M02 compound treatment 36240.0 -5340.0 -0.31 38920.0 -6610.0 -0.5 -0.5723 -0.9732 3179166 Maybridge4_002730 CCOC(=O)c1cncc(C#CCOC(=O)c2ccc(Cl)cn2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M03 compound treatment 25400.0 -16200.0 -0.94 30920.0 -14600.0 -1.11 -1.4446 -0.9966 3064603 Maybridge4_002731 CN1c2sc(C)c(C)c2-c3nc(SCC(=O)C(C)(C)C)ncc3S1(=O)=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M04 compound treatment 18400.0 -23200.0 -1.34 29400.0 -16100.0 -1.22 -1.8127 -0.9989 3179167 Maybridge4_002732 Clc1cc(Cl)cc(NC(=O)Nc2cc(n[nH]2)c3ccccc3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M05 compound treatment 31520.0 -10100.0 -0.58 39360.0 -6170.0 -0.47 -0.7421 -0.994 1536304 Maybridge4_002733 Clc1ccc(cc1)c2csc(COc3ccc4nonc4c3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M06 compound treatment 31320.0 -10300.0 -0.59 42080.0 -3450.0 -0.26 -0.6047 -0.9318 3179168 Maybridge4_002734 O=S(=O)(/C(=C/N1CCC(CC1)n2cccc2)/C#N)c3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M07 compound treatment 31000.0 -10600.0 -0.61 39880.0 -5650.0 -0.43 -0.7356 -0.9845 1203004 Maybridge4_002735 Cn1c(S)nnc1CC2Sc3ccccc3NC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M08 compound treatment 16800.0 -24800.0 -1.44 23600.0 -21900.0 -1.66 -2.1887 -0.9974 1245628 Maybridge4_002736 CCCn1c(=O)c(C#N)nn(c2ccc(OC)cc2)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M09 compound treatment 24880.0 -16700.0 -0.97 36280.0 -9250.0 -0.7 -1.179 -0.9874 1544442 Maybridge4_002737 CCOC(=O)NC(=O)c1cn(Cc2ccco2)c(=O)n(Cc3ccccc3)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M10 compound treatment 32040.0 -9540.0 -0.55 36480.0 -9050.0 -0.68 -0.875 -0.9943 3064605 Maybridge4_002738 FC(F)(F)Oc1ccc(NC(=O)OC2CN(C2)C(c3ccccc3)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M11 compound treatment 27280.0 -14300.0 -0.83 36880.0 -8650.0 -0.65 -1.0486 -0.9932 3179169 Maybridge4_002739 Cn1c(CSc2cc(nc3ccccc23)C(F)(F)F)nnc1SCC(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M12 compound treatment 25840.0 -15700.0 -0.91 32440.0 -13100.0 -0.99 -1.3452 -0.9991 3179170 Maybridge4_002740 Cc1ccc2nc(cc(N3CCN(CC3)/C=C(/C#N)\S(=O)(=O)c4ccccn4)c2c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M13 compound treatment 19480.0 -22100.0 -1.28 25000.0 -20500.0 -1.55 -2.004 -0.9954 3064606 Maybridge4_002741 COC(=O)c1scc2c(Sc3ccc(Cl)cc3)cc(nc12)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M14 compound treatment 26840.0 -14700.0 -0.85 33680.0 -11800.0 -0.9 -1.2379 -0.9997 1624356 Maybridge4_002742 Cn1c(S)nnc1CSC2CN(C2)C(c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M15 compound treatment 28000.0 -13600.0 -0.79 30320.0 -15200.0 -1.15 -1.3702 -0.9827 1609003 Maybridge4_002743 Clc1ccc(Cn2ccnc2COC(=O)c3ccccc3Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M16 compound treatment 33320.0 -8260.0 -0.48 35560.0 -9970.0 -0.75 -0.8718 -0.9758 3179171 Maybridge4_002744 CCOC(=O)N1CCC(CC1)N/C=C(\C#N)/S(=O)(=O)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M17 compound treatment 14560.0 -27000.0 -1.57 17600.0 -27900.0 -2.11 -2.6016 -0.9891 3064607 Maybridge4_002745 Clc1ccc(SC2CS(=O)(=O)c3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M18 compound treatment 32040.0 -9540.0 -0.55 34200.0 -11300.0 -0.86 -0.997 -0.9774 3179261 Maybridge4_002746 COc1ccc(cc1OC)S(=O)(=O)N(CCC(=O)O)Cc2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M19 compound treatment 17360.0 -24200.0 -1.4 22200.0 -23300.0 -1.77 -2.2407 -0.9935 3064609 Maybridge4_002747 CC(C)(C)S(=O)(=O)/C(=C/N1CCN(CC1)C(c2ccccc2)c3ccccc3)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M20 compound treatment 40120.0 -1460.0 -0.08 38880.0 -6650.0 -0.5 -0.4155 -0.8142 1049769 Maybridge4_002748 CC(C)NC(=O)c1ccccc1N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M21 compound treatment 34520.0 -7060.0 -0.41 40160.0 -5370.0 -0.41 -0.5764 -1.0 3063912 Maybridge4_002749 CCOC(=O)C1CCN(CC1)/C=C(\C#N)/S(=O)(=O)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M22 compound treatment 34960.0 -6620.0 -0.38 35360.0 -10200.0 -0.77 -0.8153 -0.9482 1471006 Maybridge4_002750 Nc1cc(=O)n(Cc2ccccc2)c(=O)n1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M23 mock treatment 40760.0 -815.0 -0.05 38400.0 -7130.0 -0.54 -0.4149 -0.7661 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 M24 mock treatment 38920.0 -2660.0 -0.15 40160.0 -5370.0 -0.41 -0.3961 -0.9116 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N01 compound treatment 42480.0 905.0 0.05 49600.0 4070.0 0.31 0.255 0.8157 3063913 Maybridge4_002751 Cn1c(SCC(=O)NCC=C)nnc1c2ccc3nonc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N02 compound treatment 19920.0 -21700.0 -1.25 20640.0 -24900.0 -1.88 -2.2193 -0.9805 3063914 Maybridge4_002752 Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)Nc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N03 compound treatment 21720.0 -19900.0 -1.15 27520.0 -18000.0 -1.36 -1.7773 -0.9964 1156673 Maybridge4_002753 O=S(=O)(N1CCC(CC1)C(c2ccccc2)c3ccccc3)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N04 compound treatment 8800.0 -32800.0 -1.9 13800.0 -31700.0 -2.4 -3.041 -0.9932 3063915 Maybridge4_002754 CNC(=O)c1csc(Cc2c(Cl)sc3ccc(Cl)cc23)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N05 compound treatment 32400.0 -9180.0 -0.53 40240.0 -5290.0 -0.4 -0.659 -0.9902 1656700 Maybridge4_002755 COc1ccc(cc1)n2c(N)cc(=O)[nH]c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N06 compound treatment 20360.0 -21200.0 -1.23 26480.0 -19000.0 -1.44 -1.8887 -0.9968 3063916 Maybridge4_002756 CN(c1ccccc1)S(=O)(=O)c2sc3ccc(Cl)cc3c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N07 compound treatment 14960.0 -26600.0 -1.54 27840.0 -17700.0 -1.34 -2.0371 -0.9975 3179262 Maybridge4_002757 CCOC(=O)N1CCN(CC1)c2cc(nc3c(Cl)cccc23)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N08 compound treatment 28320.0 -13300.0 -0.77 35240.0 -10300.0 -0.78 -1.0937 -1.0 3179263 Maybridge4_002758 COc1ccc(OC(=O)/C=C/c2sc3ccccc3c2C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N09 compound treatment 15720.0 -25900.0 -1.5 24000.0 -21500.0 -1.63 -2.2115 -0.9991 3063917 Maybridge4_002759 CCOC(=O)c1ccc2nc(cc(NC3CCN(Cc4ccccc4)CC3)c2c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N10 compound treatment 22200.0 -19400.0 -1.12 27040.0 -18500.0 -1.4 -1.7833 -0.994 3179264 Maybridge4_002760 CNC(=S)NCc1sc2ccccc2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N11 compound treatment 7920.0 -33700.0 -1.95 9920.0 -35600.0 -2.7 -3.2847 -0.9874 1569047 Maybridge4_002761 CCc1ccc2[nH]c(cc2c1)C(=O)NCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N12 compound treatment 23480.0 -18100.0 -1.05 32800.0 -12700.0 -0.96 -1.4226 -0.9991 3063918 Maybridge4_002762 Cc1nc2cc(nn2c(C)c1Sc3nccc(n3)c4cccnc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N13 compound treatment 2960.0 -38600.0 -2.24 4000.0 -41500.0 -3.14 -3.8048 -0.9861 1306797 Maybridge4_002763 COc1cc2CCN=C(c3ccc(Cl)cc3)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N14 compound treatment 19400.0 -22200.0 -1.28 19160.0 -26400.0 -2.0 -2.3198 -0.9773 3063920 Maybridge4_002764 C(N1CCC(=N1)c2cccs2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N15 compound treatment 15480.0 -26100.0 -1.51 17120.0 -28400.0 -2.15 -2.5896 -0.9851 3179265 Maybridge4_002765 CC(C)(C)Sc1nc2ccccc2[nH]c1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N16 compound treatment 31680.0 -9900.0 -0.57 36960.0 -8570.0 -0.65 -0.864 -0.9981 1707053 Maybridge4_002766 CCOC(=O)NC(=S)c1ccc(OC)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N17 compound treatment 20640.0 -20900.0 -1.21 24680.0 -20800.0 -1.58 -1.9736 -0.9915 3179266 Maybridge4_002767 Clc1cccc(c1)C(=O)Nc2nccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N18 compound treatment 27640.0 -13900.0 -0.81 32600.0 -12900.0 -0.98 -1.2629 -0.9954 1022738 Maybridge4_002768 NS(=O)(=O)c1ccc(Cl)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N19 compound treatment 30960.0 -10600.0 -0.62 34680.0 -10800.0 -0.82 -1.0155 -0.9899 3179267 Maybridge4_002769 Cc1nnsc1c2nnc(S)n2C3CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N20 compound treatment 30360.0 -11200.0 -0.65 29960.0 -15600.0 -1.18 -1.2928 -0.9606 1602154 Maybridge4_002770 CC1CN(CC(C)O1)c2ccc(NC(=S)Nc3ccc(cc3)N4CC(C)OC(C)C4)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N21 compound treatment 32560.0 -9020.0 -0.52 34920.0 -10600.0 -0.8 -0.9372 -0.9783 1095185 Maybridge4_002771 Nc1c(sc2ncccc12)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N22 compound treatment 35120.0 -6460.0 -0.37 36360.0 -9170.0 -0.69 -0.7552 -0.9579 3063921 Maybridge4_002772 OCCNC(=S)NC1CCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N23 mock treatment 37480.0 -4100.0 -0.24 37920.0 -7610.0 -0.58 -0.575 -0.9231 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 N24 mock treatment 42120.0 545.0 0.03 42680.0 -2850.0 -0.22 -0.1301 -0.5972 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O01 compound treatment 47240.0 5670.0 0.33 51000.0 5470.0 0.41 0.5249 0.9934 1227681 Maybridge4_002773 CSc1ncc(C(=O)NN)n1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O02 compound treatment 43480.0 1910.0 0.11 47960.0 2430.0 0.18 0.2082 0.9701 3179268 Maybridge4_002774 Cn1c(CN2C(=O)CSc3ccc(cc23)C(F)(F)F)nnc1SCc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O03 compound treatment 38640.0 -2940.0 -0.17 44200.0 -1330.0 -0.1 -0.1914 -0.9686 1733846 Maybridge4_002775 CNC(=O)c1cc(Br)cc2CCOc21 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O04 compound treatment 36200.0 -5380.0 -0.31 40640.0 -4890.0 -0.37 -0.4819 -0.9963 3179269 Maybridge4_002776 FC(F)(F)Oc1ccc(NC(=O)Nc2cc(n[nH]2)c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O05 compound treatment 43160.0 1590.0 0.09 45440.0 -88.8 -0.01 0.0602 0.6536 3063922 Maybridge4_002777 CCOC(=O)c1sc(COc2ccc3nonc3c2)nc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O06 compound treatment 35800.0 -5780.0 -0.33 45000.0 -529.0 -0.04 -0.2649 -0.7861 3179270 Maybridge4_002778 CC(C)(C)S(=O)(=O)/C(=C/N1CCC(CC1)n2cccc2)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O07 compound treatment 27640.0 -13900.0 -0.81 30840.0 -14700.0 -1.11 -1.3571 -0.9876 3063923 Maybridge4_002779 CCSc1cc(nc2cc(nn12)C(C)(C)C)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O08 compound treatment 15640.0 -25900.0 -1.5 22600.0 -22900.0 -1.74 -2.2897 -0.9974 3063924 Maybridge4_002780 CSc1nn(cc1C(=O)Nc2ccc(Cl)cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O09 compound treatment 32880.0 -8700.0 -0.5 41000.0 -4530.0 -0.34 -0.5986 -0.9824 1030103 Maybridge4_002781 O=c1[nH]c(=O)n(cc1C#N)C2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O10 compound treatment 38040.0 -3540.0 -0.2 38480.0 -7050.0 -0.53 -0.5221 -0.9135 1309716 Maybridge4_002782 CSc1nc2c(Cl)cccc2c3n(C)[nH]c(=O)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O11 compound treatment 35800.0 -5780.0 -0.33 41200.0 -4330.0 -0.33 -0.4683 -0.9999 1606150 Maybridge4_002783 Cc1[nH]c2ccccc2c1SCC(=O)NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O12 compound treatment 31800.0 -9780.0 -0.57 36840.0 -8690.0 -0.66 -0.8655 -0.9972 1579140 Maybridge4_002784 CCOC(=O)Cn1n(C)c2c(cnc3n(C)nc(C)c32)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O13 compound treatment 36400.0 -5180.0 -0.3 41160.0 -4370.0 -0.33 -0.4458 -0.9988 1697318 Maybridge4_002785 CCOC(=O)Cn1c(=O)c(cn(C(C)C)c1=O)C(=S)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O14 compound treatment 9000.0 -32600.0 -1.89 10560.0 -35000.0 -2.65 -3.2062 -0.9863 1214988 Maybridge4_002786 Clc1ccc(OC(=O)c2c(nnc3ccccc23)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O15 compound treatment 24120.0 -17500.0 -1.01 30800.0 -14700.0 -1.11 -1.5034 -0.9988 3063958 Maybridge4_002787 COc1cc(nc2ccc(C#CCOC(=O)Nc3ccccc3)cc12)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O16 compound treatment 11040.0 -30500.0 -1.77 16840.0 -28700.0 -2.17 -2.7865 -0.9948 3063959 Maybridge4_002788 Clc1ccc(SCc2n[nH]c(=O)c3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O17 compound treatment 34200.0 -7380.0 -0.43 40160.0 -5370.0 -0.41 -0.5895 -0.9997 1427896 Maybridge4_002789 Cc1ccc(cc1)S(=O)(=O)C2CS(=O)(=O)c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O18 compound treatment 31520.0 -10100.0 -0.58 37280.0 -8250.0 -0.62 -0.8534 -0.9994 3063960 Maybridge4_002790 COc1ccc(cc1OC)S(=O)(=O)N(CCC#N)C2CCCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O19 compound treatment 38240.0 -3340.0 -0.19 40360.0 -5170.0 -0.39 -0.4133 -0.9471 1698976 Maybridge4_002791 Cn1c(=O)c(cn(c2ccccc2)c1=O)c3nc(cs3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O20 compound treatment 36200.0 -5380.0 -0.31 42560.0 -2970.0 -0.22 -0.3791 -0.9872 3179271 Maybridge4_002792 CCOC(=O)C1CCC(N1C(=O)Nc2ccc(Cl)cc2)C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O21 compound treatment 28360.0 -13200.0 -0.77 30960.0 -14600.0 -1.1 -1.3212 -0.9841 3063961 Maybridge4_002793 FC(F)(F)c1cccc(NC(=O)CN2C(=O)CSc3ccc(cc23)C(F)(F)F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O22 compound treatment 24440.0 -17100.0 -0.99 27600.0 -17900.0 -1.36 -1.6616 -0.9882 1142886 Maybridge4_002794 Nc1nc(ncc1S(=O)(=O)c2ccccc2)C3COc4ccccc4O3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O23 mock treatment 39560.0 -2020.0 -0.12 50640.0 5110.0 0.39 0.191 0.4727 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 O24 mock treatment 45280.0 3710.0 0.21 45520.0 -8.75 0.0 0.1513 0.7049 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P01 compound treatment 43680.0 2110.0 0.12 47440.0 1910.0 0.14 0.1885 0.9964 1672516 Maybridge4_002795 O=C(Nc1ccc2nonc2c1)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P02 compound treatment 2120.0 -39500.0 -2.29 3800.0 -41700.0 -3.16 -3.8499 -0.9874 3179272 Maybridge4_002796 FC(F)(F)c1ccccc1NC(=S)Nc2ccc3C=CS(=O)(=O)c3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P03 compound treatment 38360.0 -3220.0 -0.19 47800.0 2270.0 0.17 -0.0101 -0.04 3063964 Maybridge4_002797 CCCn1c(=O)n(c2ccccc2C)c3[nH]cnc3c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P04 compound treatment 30800.0 -10800.0 -0.62 38320.0 -7210.0 -0.55 -0.8273 -0.9977 1153341 Maybridge4_002798 Cc1c(CC(=O)NN)sc2ccc(Cl)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P05 compound treatment 33600.0 -7980.0 -0.46 40640.0 -4890.0 -0.37 -0.5884 -0.9939 1289003 Maybridge4_002799 Cc1ccccc1n2ccc(=O)[nH]c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P06 compound treatment 31920.0 -9660.0 -0.56 41280.0 -4250.0 -0.32 -0.623 -0.9655 3179273 Maybridge4_002800 Cc1c(sc2ccc(Cl)cc12)C(=O)CC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P07 compound treatment 35280.0 -6300.0 -0.36 39280.0 -6250.0 -0.47 -0.5924 -0.9917 3063965 Maybridge4_002801 CSc1nnc(CNC(=O)OC(C)(C)C)n1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P08 compound treatment 22000.0 -19600.0 -1.13 29920.0 -15600.0 -1.18 -1.6374 -0.9998 3179274 Maybridge4_002802 Cc1c(COC(=O)c2ccccc2)sc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P09 compound treatment 31000.0 -10600.0 -0.61 34560.0 -11000.0 -0.83 -1.0203 -0.9888 3179275 Maybridge4_002803 Cn1c(CNC(=O)c2cccs2)nnc1SCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P10 compound treatment 29600.0 -12000.0 -0.69 37360.0 -8170.0 -0.62 -0.9278 -0.9983 3063968 Maybridge4_002804 Cc1c(CNC(=O)c2ccc(cc2)C(F)(F)F)sc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P11 compound treatment 9240.0 -32300.0 -1.87 11960.0 -33600.0 -2.54 -3.1214 -0.9888 1496234 Maybridge4_002805 CCc1ccc2[nH]c(cc2c1)C(=O)NC(C)COC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P12 compound treatment 33960.0 -7620.0 -0.44 38840.0 -6690.0 -0.51 -0.67 -0.9976 1637130 Maybridge4_002806 Clc1ccc(cc1)N2N=C(CSc3nccc(n3)c4cccnc4)CC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P13 compound treatment 20720.0 -20900.0 -1.21 25840.0 -19700.0 -1.49 -1.9082 -0.9946 3179276 Maybridge4_002807 Clc1ccc(cc1)c2ccc(s2)C(=O)OCc3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P14 compound treatment 27160.0 -14400.0 -0.84 32600.0 -12900.0 -0.98 -1.2826 -0.9969 3063969 Maybridge4_002808 CN1CCC(=N1)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P15 compound treatment 2520.0 -39100.0 -2.26 5920.0 -39600.0 -3.0 -3.72 -0.9904 3179277 Maybridge4_002809 FC(F)(F)c1ccc(CNC(=O)N/C=C/c2cccs2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P16 compound treatment 27200.0 -14400.0 -0.83 31520.0 -14000.0 -1.06 -1.3387 -0.9929 3063970 Maybridge4_002810 Oc1nnc(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P17 compound treatment 16880.0 -24700.0 -1.43 21520.0 -24000.0 -1.82 -2.2968 -0.993 3179278 Maybridge4_002811 COc1ccc(cc1)c2nc(cs2)c3ccc(C)cc3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P18 compound treatment 27160.0 -14400.0 -0.84 36920.0 -8610.0 -0.65 -1.0513 -0.9925 1676105 Maybridge4_002812 COc1ccc(cc1)c2nc(nc(=O)[nH]2)c3ccncc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P19 compound treatment 32680.0 -8900.0 -0.52 32320.0 -13200.0 -1.0 -1.0714 -0.9525 3063971 Maybridge4_002813 OCc1cnc(S)n1Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P20 compound treatment 31280.0 -10300.0 -0.6 35040.0 -10500.0 -0.79 -0.9832 -0.9901 1134458 Maybridge4_002814 CC1CN(CC(C)O1)c2ccc(NC(=S)NN)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P21 compound treatment 33200.0 -8380.0 -0.49 33720.0 -11800.0 -0.89 -0.9752 -0.9588 3063972 Maybridge4_002815 Cc1ccc2sc(cc2c1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P22 compound treatment 5720.0 -35900.0 -2.08 5840.0 -39700.0 -3.0 -3.5932 -0.9838 3063973 Maybridge4_002816 CCCc1ccc(NC(=S)OCC)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P23 mock treatment 36120.0 -5460.0 -0.32 39800.0 -5730.0 -0.43 -0.5301 -0.9879 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2056 P24 mock treatment 35760.0 -5820.0 -0.34 41920.0 -3610.0 -0.27 -0.4314 -0.9946 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A01 compound treatment 47400.0 -1250.0 -0.07 43240.0 -61.3 0.0 -0.0546 -0.7507 3210829 TimTec1_003521 CCC(Sc1nncn1C)C(=O)Nc2ccc(OC(F)(F)F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A02 compound treatment 52880.0 4230.0 0.24 43320.0 18.8 0.0 0.1741 0.7112 1243143 TimTec1_003522 Cc1nc2ccccc2n1c3ccc(cc3)S(=O)(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A03 compound treatment 10800.0 -37900.0 -2.19 7000.0 -36300.0 -2.75 -3.4938 -0.9938 1268944 TimTec1_003523 CSc1nc2cc(Oc3ccc4ccccc4c3)c(Cl)cc2[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A04 compound treatment 37720.0 -10900.0 -0.63 22120.0 -21200.0 -1.6 -1.5816 -0.9175 3085107 TimTec1_003524 O=C(Nc1ccc2ccccc2c1)/C(=C/c3ccco3)/c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A05 compound treatment 9520.0 -39100.0 -2.27 8960.0 -34300.0 -2.6 -3.4413 -0.9977 3210949 TimTec1_003525 O=C1OC2(CCCC2)OC(=O)C1=Cc3ccc(OCc4ccccc4)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A06 compound treatment 5400.0 -43300.0 -2.51 5360.0 -37900.0 -2.87 -3.8028 -0.9977 3210950 TimTec1_003526 Clc1ccc(cc1)C(=O)/C=C/2\C(=O)Nc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A07 compound treatment 51720.0 3070.0 0.18 40800.0 -2500.0 -0.19 -0.0083 -0.0318 1188087 TimTec1_003527 COc1cc2CCN3C(C(C)C(=O)C4=C3CSCC4=O)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A08 compound treatment 46320.0 -2330.0 -0.14 37320.0 -5980.0 -0.45 -0.4157 -0.8799 3210951 TimTec1_003528 S=C(N1CCCC1)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A09 compound treatment 43280.0 -5370.0 -0.31 42440.0 -861.0 -0.07 -0.2663 -0.837 1606147 TimTec1_003529 Cc1oc(c(CN2CCOCC2)c1C(=O)O)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A10 compound treatment 7200.0 -41500.0 -2.4 6920.0 -36400.0 -2.75 -3.6456 -0.9977 3085108 TimTec1_003530 Cc1ccc(C)c(c1)c2csc(N)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A11 compound treatment 27040.0 -21600.0 -1.25 19360.0 -23900.0 -1.81 -2.1669 -0.9837 1212994 TimTec1_003531 Cn1cnnc1SCC(=O)N2c3ccccc3Sc4ccc(Cl)cc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A12 compound treatment 39160.0 -9490.0 -0.55 33600.0 -9700.0 -0.73 -0.9082 -0.9899 1431522 TimTec1_003532 CCOC(=O)c1oc2ccc(OC)cc2c1CN3CCN(C)CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A13 compound treatment 22920.0 -25700.0 -1.49 12960.0 -30300.0 -2.3 -2.6782 -0.9781 1733965 TimTec1_003533 CCC1(C)Oc2ccc(NC(=O)c3cc(F)c(F)cc3Cl)cc2O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A14 compound treatment 40720.0 -7930.0 -0.46 39840.0 -3460.0 -0.26 -0.5103 -0.9645 1590249 TimTec1_003534 CC1CCC2C(C)(CO)C(O)CCC2(C)C31CCC(C)(CO)O3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A15 compound treatment 42280.0 -6370.0 -0.37 34880.0 -8420.0 -0.64 -0.7119 -0.9663 1408570 TimTec1_003535 OCCCN1C(=O)c2ccccc2C1(O)Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A16 compound treatment 49240.0 586.0 0.03 36360.0 -6940.0 -0.53 -0.3475 -0.66 1133958 TimTec1_003536 O=C(COC(=O)CSc1nnc([nH]1)c2ccccc2)NC3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A17 compound treatment 45240.0 -3410.0 -0.2 39680.0 -3620.0 -0.27 -0.3337 -0.9872 3085112 TimTec1_003537 COC(=O)c1c(N)oc2c(c3cccc(c3)C(F)(F)F)c4c(C(=O)OC)c(N)oc4cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A18 compound treatment 25400.0 -23300.0 -1.35 21480.0 -21800.0 -1.65 -2.1206 -0.9949 1479296 TimTec1_003538 CCc1cccc2c(CCNC(=O)COc3ccc(F)cc3F)c(C)[nH]c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A19 compound treatment 43520.0 -5130.0 -0.3 39640.0 -3660.0 -0.28 -0.4063 -0.9994 1638558 TimTec1_003539 COC(=O)c1cc(nc2ccccc12)N3CCNCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A20 compound treatment 45560.0 -3090.0 -0.18 37560.0 -5740.0 -0.43 -0.434 -0.9233 3085182 TimTec1_003540 Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)NCCOC2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A21 compound treatment 42240.0 -6410.0 -0.37 34840.0 -8460.0 -0.64 -0.7156 -0.9665 1636785 TimTec1_003541 CC(C)C(=O)Nc1nc(OC(=O)N(c2ccccc2)c3ccccc3)c4nc[nH]c4n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A22 compound treatment 3240.0 -45400.0 -2.63 1800.0 -41500.0 -3.14 -4.0818 -0.9961 1508388 TimTec1_003542 O=C(OCc1ccc2nonc2c1)c3c4CCCCc4nc5ccccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A23 mock treatment 49400.0 746.0 0.04 48280.0 4980.0 0.38 0.2971 0.7831 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 A24 mock treatment 48000.0 -654.0 -0.04 53120.0 9820.0 0.74 0.4988 0.6702 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B01 compound treatment 43840.0 -4810.0 -0.28 27320.0 -16000.0 -1.21 -1.0526 -0.8479 3085184 TimTec1_003543 CC12CCC(=O)N2c3ccccc3C(=O)N1c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B02 compound treatment 52080.0 3430.0 0.2 40280.0 -3020.0 -0.23 -0.0213 -0.0705 1731017 TimTec1_003544 CCCCc1c(C)nc2c(OC)cccc2c1SCCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B03 compound treatment 22080.0 -26600.0 -1.54 15320.0 -28000.0 -2.12 -2.5863 -0.9877 1552863 TimTec1_003545 Fc1ccc(Sc2c(F)c(F)nc(N3CCNCC3)c2F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B04 compound treatment 56000.0 7350.0 0.43 49600.0 6300.0 0.48 0.6381 0.9984 3210952 TimTec1_003546 COc1ccc2C(Nc3nc4ccc(OC(F)(F)F)cc4s3)OC(=O)c2c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B05 compound treatment 41600.0 -7050.0 -0.41 27360.0 -15900.0 -1.21 -1.1422 -0.8966 3085186 TimTec1_003547 Fc1ccc(cc1)N2C(=O)/C(=C/N3CCCCC3)/SC2=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B06 compound treatment 55080.0 6430.0 0.37 34800.0 -8500.0 -0.64 -0.1917 -0.2579 3210953 TimTec1_003548 COC(=O)c1ccc(CSc2nnc3n(N)cnn23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B07 compound treatment 33280.0 -15400.0 -0.89 22040.0 -21300.0 -1.61 -1.7678 -0.9611 3085188 TimTec1_003549 Cc1cc(nc(SCc2ccccc2)c1C#N)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B08 compound treatment 15080.0 -33600.0 -1.95 6520.0 -36800.0 -2.78 -3.3441 -0.9846 1390724 TimTec1_003550 COC(c1cccs1)c2c(C)[nH]c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B09 compound treatment 46520.0 -2130.0 -0.12 33520.0 -9780.0 -0.74 -0.6109 -0.8139 3210954 TimTec1_003551 Oc1ccccc1c2nc(O)c3c4CCCCc4sc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B10 compound treatment 46680.0 -1970.0 -0.11 35120.0 -8180.0 -0.62 -0.5188 -0.8238 3085190 TimTec1_003552 Cc1ccc(/C=C\2/SC(=O)N(CC(=O)Nc3ccc(C)cc3)C2=O)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B11 compound treatment 38960.0 -9690.0 -0.56 38600.0 -4700.0 -0.36 -0.6488 -0.9758 3210955 TimTec1_003553 Cc1sc2nc(nc(O)c2c1C)c3ccccc3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B12 compound treatment 28920.0 -19700.0 -1.14 26600.0 -16700.0 -1.26 -1.7024 -0.9987 1921968 TimTec1_003554 Cc1c(Cl)cccc1NC(=O)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B13 compound treatment 15120.0 -33500.0 -1.94 13560.0 -29700.0 -2.25 -2.9657 -0.9973 1218019 TimTec1_003555 CC(NC(=O)C1CCCN1S(=O)(=O)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B14 compound treatment 43920.0 -4730.0 -0.27 37920.0 -5380.0 -0.41 -0.482 -0.9815 3085194 TimTec1_003556 CCOc1cc(/C=C\2/S\C(=N/C)\N(C)C2=O)ccc1OCC(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B15 compound treatment 43720.0 -4930.0 -0.29 37280.0 -6020.0 -0.46 -0.5244 -0.9747 1154943 TimTec1_003557 CC1C(=O)OC(c2ccc(Br)cc2)C(C)(C)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B16 compound treatment 34840.0 -13800.0 -0.8 18800.0 -24500.0 -1.85 -1.8773 -0.9294 3085196 TimTec1_003558 Cc1ccc(SCC(=O)N[C@@H]2C[C@H]3CC[C@@H]2C3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B17 compound treatment 46680.0 -1970.0 -0.11 37360.0 -5940.0 -0.45 -0.3989 -0.8596 1526862 TimTec1_003559 Cc1cc(Cl)ccc1OCC(=O)Nc2sc3CCCc3c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B18 compound treatment 42280.0 -6370.0 -0.37 38040.0 -5260.0 -0.4 -0.5427 -0.9993 1571119 TimTec1_003560 OC(=O)CCC(=O)Nc1ccccn1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B19 compound treatment 43560.0 -5090.0 -0.3 37640.0 -5660.0 -0.43 -0.5117 -0.9834 1209861 TimTec1_003561 Cc1ccc(cc1)N(CC(O)CN2C(=O)NC(C)(C)C2=O)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B20 compound treatment 8560.0 -40100.0 -2.32 7360.0 -35900.0 -2.72 -3.5663 -0.9969 1692625 TimTec1_003562 Cc1ccc(cc1)C(=O)Nc2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B21 compound treatment 36520.0 -12100.0 -0.7 39280.0 -4020.0 -0.3 -0.7123 -0.9299 3085199 TimTec1_003563 CC(C)Cc1ccc(cc1)c2cc(O)[nH]n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B22 compound treatment 43640.0 -5010.0 -0.29 43120.0 -181.0 -0.01 -0.2151 -0.7397 1410378 TimTec1_003564 OC(=O)c1ccc(O)c(SCN2CCCCC2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B23 mock treatment 45480.0 -3170.0 -0.18 48600.0 5300.0 0.4 0.1536 0.3481 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 B24 mock treatment 43840.0 -4810.0 -0.28 47680.0 4380.0 0.33 0.0372 0.0858 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C01 compound treatment 51640.0 2990.0 0.17 43920.0 619.0 0.05 0.1555 0.8673 3085266 TimTec1_003565 FC(F)(F)Oc1ccc(NC(=O)COC(=O)/C=C\c2ccco2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C02 compound treatment 27680.0 -21000.0 -1.22 16440.0 -26900.0 -2.03 -2.297 -0.9697 3085268 TimTec1_003566 C[C@H]1[C@@H]2CC(C)(C)CC[C@]2(CO)CCC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C03 compound treatment 4280.0 -44400.0 -2.57 8680.0 -34600.0 -2.62 -3.671 -1.0 1199129 TimTec1_003567 CN1CCN(CC1)c2ccc(Nc3ccnc4cc(Cl)ccc34)cc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C04 compound treatment 39360.0 -9290.0 -0.54 31920.0 -11400.0 -0.86 -0.9899 -0.9744 3085270 TimTec1_003568 CC1=CC(c2ccc(F)cc2)C(CC1)(C(=O)O)C(=O)n3nc(C)cc3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C05 compound treatment 54040.0 5390.0 0.31 37640.0 -5660.0 -0.43 -0.0823 -0.1553 3210956 TimTec1_003569 CC(=O)NC(N1CCCC1=O)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C06 compound treatment 52080.0 3430.0 0.2 33400.0 -9900.0 -0.75 -0.3896 -0.5025 1250474 TimTec1_003570 OC(=O)Cc1csc2nc(cn12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C07 compound treatment 41440.0 -7210.0 -0.42 31760.0 -11500.0 -0.87 -0.9133 -0.943 1127712 TimTec1_003571 Nn1c(CSc2nc3ccccc3o2)nnc1CSc4nc5ccccc5o4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C08 compound treatment 41080.0 -7570.0 -0.44 33080.0 -10200.0 -0.77 -0.8574 -0.9639 3085273 TimTec1_003572 O/N=C/c1ccc(cc1)N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C09 compound treatment 44440.0 -4210.0 -0.24 30560.0 -12700.0 -0.96 -0.8546 -0.859 3210957 TimTec1_003573 CC(C)C1C(=NN(C1=S)c2ccccc2)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C10 compound treatment 22800.0 -25900.0 -1.5 17280.0 -26000.0 -1.97 -2.4519 -0.9909 1006805 TimTec1_003574 NC(C(O)c1ccccc1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C11 compound treatment 38200.0 -10500.0 -0.61 30200.0 -13100.0 -0.99 -1.1295 -0.972 1375728 TimTec1_003575 COCc1cc(C)nc2sc(C(O)c3ccccc3)c(NC(=O)c4ccco4)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C12 compound treatment 43160.0 -5490.0 -0.32 31240.0 -12100.0 -0.91 -0.8706 -0.9005 1319536 TimTec1_003576 C=CCn1c(nn(CCC#N)c1=S)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C13 compound treatment 45320.0 -3330.0 -0.19 32800.0 -10500.0 -0.79 -0.6986 -0.8541 1138165 TimTec1_003577 O=C(NC1CC1)c2n[nH]c(=O)c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C14 compound treatment 36560.0 -12100.0 -0.7 29200.0 -14100.0 -1.07 -1.2502 -0.9792 1631186 TimTec1_003578 CSc1ncnc2n(CN3CCOCC3)cnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C15 compound treatment 31320.0 -17300.0 -1.0 25040.0 -18300.0 -1.38 -1.6875 -0.9877 3085277 TimTec1_003579 CCN(CC)c1nc(OC)nc(C#N)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C16 compound treatment 11040.0 -37600.0 -2.18 10800.0 -32500.0 -2.46 -3.2806 -0.9982 1237261 TimTec1_003580 C(Nc1nc(NC2CCCCC2)nc(n1)N3CCOCC3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C17 compound treatment 7880.0 -40800.0 -2.36 10160.0 -33100.0 -2.51 -3.4443 -0.9995 1373918 TimTec1_003581 COc1ccc(cc1)C(=O)Nc2ccccc2C3(C)CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C18 compound treatment 4920.0 -43700.0 -2.53 4640.0 -38700.0 -2.93 -3.861 -0.9974 1306307 TimTec1_003582 Cn1c(=S)n(CCSc2nc3ccccc3n2c4ccccc4)c5ccccc15 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C19 compound treatment 39160.0 -9490.0 -0.55 38800.0 -4500.0 -0.34 -0.6299 -0.9735 3085281 TimTec1_003583 Cc1ccccc1n2c(n[nH]c2=S)c3ccc(Br)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C20 compound treatment 37240.0 -11400.0 -0.66 35240.0 -8060.0 -0.61 -0.8991 -0.9992 1451733 TimTec1_003584 CCOC(=O)c1ccc(CNS(=O)(=O)c2ccc(cc2)S(=O)(=O)N3CCOCC3)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C21 compound treatment 37400.0 -11300.0 -0.65 40000.0 -3300.0 -0.25 -0.6377 -0.9133 1387125 TimTec1_003585 COC(C)(OCCn1c2ccccc2c3ccccc13)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C22 compound treatment 44240.0 -4410.0 -0.26 33160.0 -10100.0 -0.77 -0.7236 -0.8943 1631435 TimTec1_003586 CCOC(=O)c1ccc(CNC(=O)c2ccc(cc2)S(=O)(=O)c3ccccc3)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C23 mock treatment 48080.0 -574.0 -0.03 44000.0 699.0 0.05 0.0139 0.2224 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 C24 mock treatment 49200.0 546.0 0.03 42320.0 -981.0 -0.07 -0.0301 -0.3733 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D01 compound treatment 44320.0 -4330.0 -0.25 39000.0 -4300.0 -0.33 -0.4078 -0.9918 3211082 TimTec1_003587 COc1nc(Nc2ccccc2)nc(OCC(F)(F)F)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D02 compound treatment 56600.0 7950.0 0.46 39000.0 -4300.0 -0.33 0.0953 0.169 3085284 TimTec1_003588 Cn1c(=O)[nH]c(=O)c2n(CCC/N=C\3/CCCCN3)cnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D03 compound treatment 53000.0 4350.0 0.25 34480.0 -8820.0 -0.67 -0.2941 -0.4121 1240788 TimTec1_003589 CCOc1cc(ccc1OC)C2N(CC3N2CCc4ccccc34)S(=O)(=O)c5ccc(C)cc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D04 compound treatment 40480.0 -8170.0 -0.47 30840.0 -12500.0 -0.94 -1.0018 -0.9492 2108247 TimTec1_003590 CCOC(=O)[C@@H]1[C@@H]2NC(=O)N[C@@]1(C)Oc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D05 compound treatment 38960.0 -9690.0 -0.56 33000.0 -10300.0 -0.78 -0.9485 -0.987 1269248 TimTec1_003591 CCN(CC)C(=S)Oc1ccc(cc1)C(=O)Nc2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D06 compound treatment 42160.0 -6490.0 -0.38 36640.0 -6660.0 -0.5 -0.6226 -0.9896 3085357 TimTec1_003592 Cc1cc([nH]c(=O)c1C#N)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D07 compound treatment 12360.0 -36300.0 -2.1 11600.0 -31700.0 -2.4 -3.1837 -0.9978 1389688 TimTec1_003593 COc1cccc(c1)c2nnc(SCc3ccc(C#N)cc3Cl)n2CC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D08 compound treatment 11480.0 -37200.0 -2.15 9160.0 -34100.0 -2.58 -3.3503 -0.9959 3085358 TimTec1_003594 CCOC(=O)C1=CN(C=C(C1c2ccccc2F)C(=O)OCC)c3ccc(C)c(C)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D09 compound treatment 7120.0 -41500.0 -2.41 5160.0 -38100.0 -2.89 -3.743 -0.9959 1652064 TimTec1_003595 Fc1ccccc1CSc2nnc3c4ccccc4n(CC=C)c3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D10 compound treatment 45840.0 -2810.0 -0.16 36960.0 -6340.0 -0.48 -0.4547 -0.8969 3211083 TimTec1_003596 COc1ccc(/C=C/2\S/C(=N/c3ccc(cc3)N4CCOCC4)/N(C)C2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D11 compound treatment 39360.0 -9290.0 -0.54 32560.0 -10700.0 -0.81 -0.9557 -0.98 1144490 TimTec1_003597 COc1ccc(cc1)c2cc(nc(SCC(=O)N3CCCCC3)c2C#N)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D12 compound treatment 36920.0 -11700.0 -0.68 28840.0 -14500.0 -1.09 -1.2547 -0.9737 1614237 TimTec1_003598 CCc1ccc(NC(=O)C2(CC3CC4CC(C3)C2)C4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D13 compound treatment 31360.0 -17300.0 -1.0 23000.0 -20300.0 -1.54 -1.7951 -0.9785 1504270 TimTec1_003599 Clc1ccccc1COc2ccc(cc2)N3CC(CC3=O)C(=O)N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D14 compound treatment 45400.0 -3250.0 -0.19 38000.0 -5300.0 -0.4 -0.417 -0.9407 3085361 TimTec1_003600 Cc1cc(ccc1/C=N/n2cnnc2)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D15 compound treatment 10880.0 -37800.0 -2.19 11160.0 -32100.0 -2.43 -3.2678 -0.9986 1542891 TimTec1_003601 CN(c1ccc(Cl)cc1)S(=O)(=O)c2cccc(c2)C(=O)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D16 compound treatment 34960.0 -13700.0 -0.79 35400.0 -7900.0 -0.6 -0.9839 -0.9903 3085364 TimTec1_003602 Cc1ccc(/C=N\n2nnnc2N)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D17 compound treatment 45520.0 -3130.0 -0.18 41760.0 -1540.0 -0.12 -0.2109 -0.9771 1515864 TimTec1_003603 COC(=O)N1CCC(=O)Nc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D18 compound treatment 42640.0 -6010.0 -0.35 35040.0 -8260.0 -0.63 -0.6885 -0.9619 3211084 TimTec1_003604 COc1ccccc1N/C(=N\O)/C(=N/O)/Nc2ccccc2OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D19 compound treatment 34800.0 -13900.0 -0.8 31720.0 -11600.0 -0.88 -1.1874 -0.999 1479338 TimTec1_003605 CC1=CCC(C(C1)C(=O)Nc2ccc(cc2)c3nc4ccc(C)cc4s3)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D20 compound treatment 43640.0 -5010.0 -0.29 43400.0 98.8 0.01 -0.2001 -0.6887 1527622 TimTec1_003606 CN(C)Cc1c(O)ccc2c(=O)c(Oc3cc(C)cc(C)c3)coc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D21 compound treatment 23080.0 -25600.0 -1.48 13840.0 -29500.0 -2.23 -2.6246 -0.9803 3211085 TimTec1_003607 Fc1ccc(cc1)C(=O)/C=C\2/NCC3N(CCc4ccccc34)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D22 compound treatment 48280.0 -374.0 -0.02 49200.0 5900.0 0.45 0.3004 0.672 1154370 TimTec1_003608 Cc1ccccc1NC(=O)C2CC(O)CN2C(=O)OCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D23 mock treatment 51480.0 2830.0 0.16 43000.0 -301.0 -0.02 0.0997 0.6028 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 D24 mock treatment 52400.0 3750.0 0.22 42280.0 -1020.0 -0.08 0.0988 0.4289 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E01 compound treatment 35120.0 -13500.0 -0.78 26760.0 -16500.0 -1.25 -1.4398 -0.9746 1604889 TimTec1_003609 Cc1ccc(cc1C(=O)N2CCCCCC2)S(=O)(=O)NCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E02 compound treatment 43400.0 -5250.0 -0.3 39480.0 -3820.0 -0.29 -0.4198 -0.9997 1585521 TimTec1_003610 CCn1cc(C(=O)O)c(=O)c2cc(F)c(NN3C(SCC3=O)c4ccccc4Cl)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E03 compound treatment 30800.0 -17900.0 -1.03 14880.0 -28400.0 -2.15 -2.2527 -0.9437 3085369 TimTec1_003611 CC(N1C(=CC(C)(C)NC1=S)C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E04 compound treatment 11920.0 -36700.0 -2.13 11720.0 -31600.0 -2.39 -3.1953 -0.9983 2114263 TimTec1_003612 COc1cc2CCN(C)c3cc4cc(OC)c(OC)cc4c(c1OC)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E05 compound treatment 26280.0 -22400.0 -1.3 20720.0 -22600.0 -1.71 -2.1252 -0.9907 3085371 TimTec1_003613 CC1CCc2ccccc2N1C(=N)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E06 compound treatment 16280.0 -32400.0 -1.88 12840.0 -30500.0 -2.31 -2.9567 -0.9948 3211086 TimTec1_003614 Cc1c(/C=N/c2ccc(cc2)N3CCOCC3)c4ccccc4n1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E07 compound treatment 37960.0 -10700.0 -0.62 27040.0 -16300.0 -1.23 -1.3085 -0.9495 3211087 TimTec1_003615 COc1ccc(cc1OC)C2=Nn3cnnc3SC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E08 compound treatment 45680.0 -2970.0 -0.17 37760.0 -5540.0 -0.42 -0.4184 -0.9227 3085373 TimTec1_003616 NS(=O)(=O)c1ccc(cc1)n2cccc2/C=N/n3cnnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E09 compound treatment 51840.0 3190.0 0.18 36320.0 -6980.0 -0.53 -0.2431 -0.4343 3211088 TimTec1_003617 Cc1nn2C(=O)NC(Nc2c1c3ccccc3)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E10 compound treatment 48680.0 26.3 0.0 35200.0 -8100.0 -0.61 -0.4325 -0.7054 1518082 TimTec1_003618 CN(Cn1c(=O)oc2ccccc12)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E11 compound treatment 40120.0 -8530.0 -0.49 32960.0 -10300.0 -0.78 -0.9031 -0.9754 1594658 TimTec1_003619 COc1ccc(CCn2c3CCCc3c(=S)[nH]c2=O)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E12 compound treatment 30000.0 -18700.0 -1.08 23080.0 -20200.0 -1.53 -1.8465 -0.9855 3211089 TimTec1_003620 CCOC(=O)c1c(C)sc2c(C)c(C)[nH]c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E13 compound treatment 32400.0 -16300.0 -0.94 29000.0 -14300.0 -1.08 -1.4313 -0.9976 3084338 TimTec1_003621 COCc1cc(C)nc2sc3c(O)nc(nc3c12)c4ccccc4O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E14 compound treatment 40680.0 -7970.0 -0.46 33240.0 -10100.0 -0.76 -0.8652 -0.9713 1260196 TimTec1_003622 OC(COc1ccccc1)CSc2nc3ccccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E15 compound treatment 29400.0 -19300.0 -1.12 30040.0 -13300.0 -1.0 -1.4986 -0.9986 1328330 TimTec1_003623 CCOC(=O)CC(Nc1nc(nc(n1)N2CCOCC2)N3CCOCC3)c4ccc(C)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E16 compound treatment 38280.0 -10400.0 -0.6 38920.0 -4380.0 -0.33 -0.6595 -0.9607 3084342 TimTec1_003624 CC(=O)OCN1CCN(COC(=O)C)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E17 compound treatment 23840.0 -24800.0 -1.44 34440.0 -8860.0 -0.67 -1.4909 -0.9398 1565142 TimTec1_003625 CN(C)S(=O)(=O)c1cc(C(=O)NCC2CCCO2)c(Cl)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E18 compound treatment 40000.0 -8650.0 -0.5 39560.0 -3740.0 -0.28 -0.5548 -0.9634 1165026 TimTec1_003626 OC(=O)Cc1c([nH]c2ccccc12)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E19 compound treatment 5880.0 -42800.0 -2.48 5080.0 -38200.0 -2.89 -3.7981 -0.997 3211090 TimTec1_003627 CC(C)C(N1C(=O)c2ccccc2C1=O)C(=O)OC3CSCC3NC(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E20 compound treatment 27680.0 -21000.0 -1.22 21120.0 -22200.0 -1.68 -2.0465 -0.9874 1227495 TimTec1_003628 Fc1ccc(Oc2cc(C#N)c(C#N)cc2n3nnc4ccccc34)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E21 compound treatment 44440.0 -4210.0 -0.24 31080.0 -12200.0 -0.93 -0.8268 -0.8641 1507098 TimTec1_003629 COc1ccccc1NC(=O)NC(C)(C)c2cccc(c2)C(=C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E22 compound treatment 40400.0 -8250.0 -0.48 28560.0 -14700.0 -1.12 -1.1272 -0.9285 3084346 TimTec1_003630 CC1(C)Cc2ccccc2C(=N1)CSc3nc(cc(n3)C(F)(F)F)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E23 mock treatment 55840.0 7190.0 0.42 43360.0 58.8 0.0 0.2976 0.7146 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 E24 mock treatment 53440.0 4790.0 0.28 45240.0 1940.0 0.15 0.2999 0.9557 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F01 compound treatment 50880.0 2230.0 0.13 37040.0 -6260.0 -0.47 -0.2439 -0.4966 1683155 TimTec1_003631 Cc1cc(C(=O)N2CCCC2C(=O)O)c(C)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F02 compound treatment 12280.0 -36400.0 -2.11 5200.0 -38100.0 -2.88 -3.5295 -0.9881 1413129 TimTec1_003632 Brc1ccccc1OCc2ccc(cc2)C(=O)Nc3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F03 compound treatment 46440.0 -2210.0 -0.13 34400.0 -8900.0 -0.67 -0.5671 -0.8269 3084349 TimTec1_003633 CC1CC(n2ncnc2N1C(=O)CSc3nc4ccccc4o3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F04 compound treatment 54440.0 5790.0 0.34 40360.0 -2940.0 -0.22 0.0796 0.1979 1033523 TimTec1_003634 Nc1ncnc2n(CCO)cnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F05 compound treatment 5920.0 -42700.0 -2.48 9320.0 -34000.0 -2.57 -3.5695 -0.9998 3209122 TimTec1_003635 O/N=C/1\CCCCc2c1[nH]c3ccc(cc23)C4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F06 compound treatment 43720.0 -4930.0 -0.29 32920.0 -10400.0 -0.79 -0.7578 -0.9062 1204260 TimTec1_003636 CC1(CC2(C)CC3(CN)C1)CC(CCN)(C2)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F07 compound treatment 40640.0 -8010.0 -0.46 36280.0 -7020.0 -0.53 -0.7041 -0.9977 3209123 TimTec1_003637 COc1ccc(cc1)c2cs/c(=N\c3cc(ccc3C)C(=O)O)/o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F08 compound treatment 48160.0 -494.0 -0.03 38120.0 -5180.0 -0.39 -0.2975 -0.7567 3084352 TimTec1_003638 Clc1ccc(SCCC(=O)NCc2ccncc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F09 compound treatment 52000.0 3350.0 0.19 35200.0 -8100.0 -0.61 -0.2965 -0.4611 1270422 TimTec1_003639 CN(C)CCC(C)(O)Cc1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F10 compound treatment 38160.0 -10500.0 -0.61 27400.0 -15900.0 -1.2 -1.281 -0.95 3084354 TimTec1_003640 CCOC(=O)CN1C(=O)S/C(=C\c2ccc(o2)c3ccc(Cl)cc3Cl)/C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F11 compound treatment 42440.0 -6210.0 -0.36 35880.0 -7420.0 -0.56 -0.6518 -0.9769 1341261 TimTec1_003641 COc1ccc(cc1)N2CCN(CC2)C(=O)c3ccc(C#CC4(O)CCCCC4)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F12 compound treatment 20400.0 -28300.0 -1.64 20520.0 -22800.0 -1.72 -2.3768 -0.9997 1151583 TimTec1_003642 O=C(N1CCN(CC1)c2ccccc2)C3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F13 compound treatment 50400.0 1750.0 0.1 38840.0 -4460.0 -0.34 -0.1672 -0.4744 3084357 TimTec1_003643 CC1(CC(=O)Nc2ccccc2)NN=C(S1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F14 compound treatment 27280.0 -21400.0 -1.24 21840.0 -21500.0 -1.62 -2.0243 -0.991 3209124 TimTec1_003644 Brc1cc(/C=C(/C#N)\c2ccccc2)oc1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F15 compound treatment 41640.0 -7010.0 -0.41 39520.0 -3780.0 -0.29 -0.4897 -0.9853 3084359 TimTec1_003645 Oc1cc(nc(SCCOc2ccccc2F)n1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F16 compound treatment 35640.0 -13000.0 -0.75 33360.0 -9940.0 -0.75 -1.0652 -1.0 1917462 TimTec1_003646 Nc1cc(N)nc(SCc2ccccc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F17 compound treatment 28880.0 -19800.0 -1.15 26120.0 -17200.0 -1.3 -1.7297 -0.998 3084427 TimTec1_003647 C/C(=C/1\C(CC(=CC1=O)c2ccc(C)o2)c3ccccc3)/O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F18 compound treatment 24080.0 -24600.0 -1.42 25080.0 -18200.0 -1.38 -1.982 -0.9999 1100509 TimTec1_003648 CCOC(=O)CSc1sc(C(=O)OCC)c(N)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F19 compound treatment 45680.0 -2970.0 -0.17 42120.0 -1180.0 -0.09 -0.1851 -0.9533 1681303 TimTec1_003649 CCC(=O)Oc1cc2c(C)cc(=O)oc2cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F20 compound treatment 39720.0 -8930.0 -0.52 37280.0 -6020.0 -0.46 -0.6883 -0.998 1277376 TimTec1_003650 Brc1ccccc1OCC(=O)Nc2ccc(cc2)C(=O)OC3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F21 compound treatment 30720.0 -17900.0 -1.04 25760.0 -17500.0 -1.33 -1.6736 -0.9926 1591398 TimTec1_003651 O=c1[nH]c2ccccc2c(=O)n1CCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F22 compound treatment 52000.0 3350.0 0.19 43440.0 139.0 0.01 0.1445 0.7443 3209125 TimTec1_003652 COC(=O)Cn1nnc(c2nnn(COC(=O)C)c2c3ccccc3)c1c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F23 mock treatment 57280.0 8630.0 0.5 47760.0 4460.0 0.34 0.5921 0.9817 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 F24 mock treatment 58200.0 9550.0 0.55 44440.0 1140.0 0.09 0.452 0.8076 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G01 compound treatment 38640.0 -10000.0 -0.58 33600.0 -9700.0 -0.73 -0.9295 -0.9932 1145213 TimTec1_003653 O=C(N1CC(=O)N(OCc2ccccc2)C1c3cccs3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G02 compound treatment 35160.0 -13500.0 -0.78 29280.0 -14000.0 -1.06 -1.3033 -0.9887 3209126 TimTec1_003654 CCN(CC)c1ccc(O)c(/C=N/N2C(=O)/C(=C/c3ccco3)/N=C2c4ccccc4)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G03 compound treatment 46600.0 -2050.0 -0.12 34320.0 -8980.0 -0.68 -0.5649 -0.8184 1490785 TimTec1_003655 CC1(C)CC(CC(C)(C)N1O)NC(=O)c2ccncc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G04 compound treatment 10280.0 -38400.0 -2.22 14320.0 -29000.0 -2.19 -3.1233 -1.0 3209127 TimTec1_003656 CN(C)Cc1c(N)cc2ccccc2c1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G05 compound treatment 37480.0 -11200.0 -0.65 28360.0 -14900.0 -1.13 -1.2575 -0.965 3084709 TimTec1_003657 FC(F)(F)C1(NC(=O)N2C(=CSC2=N1)C3CC3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G06 compound treatment 32720.0 -15900.0 -0.92 27240.0 -16100.0 -1.22 -1.5124 -0.9908 3209128 TimTec1_003658 O=C1NC(=O)/C(=C\Nc2sc3CCCCc3c2C#N)/C(=O)N1Cc4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G07 compound treatment 35720.0 -12900.0 -0.75 25800.0 -17500.0 -1.32 -1.4666 -0.9636 3084710 TimTec1_003659 CSC1=NC(C)(C)CC21C=CC(=O)C(=C2)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G08 compound treatment 240.0 -48400.0 -2.8 360.0 -42900.0 -3.25 -4.2818 -0.9973 3209129 TimTec1_003660 CN(C)c1ccc(/N=C\2/C(=C(C#N)C(=O)N(CCO)C2=O)C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G09 compound treatment 41680.0 -6970.0 -0.4 27120.0 -16200.0 -1.22 -1.1518 -0.893 1338522 TimTec1_003661 N#CCCn1c(nc2ccccc12)c3cncs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G10 compound treatment 45400.0 -3250.0 -0.19 37440.0 -5860.0 -0.44 -0.447 -0.9273 1169940 TimTec1_003662 O=S(=O)(Nc1ccncc1)c2ccc3ccccc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G11 compound treatment 1280.0 -47400.0 -2.74 920.0 -42400.0 -3.21 -4.2092 -0.997 1221383 TimTec1_003663 O=C1CC(C2COC1O2)n3c(=O)oc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G12 compound treatment 29600.0 -19100.0 -1.1 22160.0 -21100.0 -1.6 -1.9122 -0.9836 1480783 TimTec1_003664 COc1ccccc1OCC(=O)NC2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G13 compound treatment 24840.0 -23800.0 -1.38 25240.0 -18100.0 -1.37 -1.9423 -1.0 1147932 TimTec1_003665 Cc1ccc(cc1)c2cc3cc(C)c(C#N)c(N4CCCCCC4)n3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G14 compound treatment 560.0 -48100.0 -2.79 560.0 -42700.0 -3.24 -4.258 -0.9972 2105438 TimTec1_003666 CC1CC(=O)N(N(C)C)C(C#N)(C#N)C1(C#N)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G15 compound treatment 37280.0 -11400.0 -0.66 37360.0 -5940.0 -0.45 -0.784 -0.9827 3084711 TimTec1_003667 CC(NC1=C(C(=O)/C=C/c2ccccc2)C(=O)CC(C)(C)C1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G16 compound treatment 37480.0 -11200.0 -0.65 40880.0 -2420.0 -0.18 -0.5874 -0.873 1284183 TimTec1_003668 CCOC(=O)N1CCN(CC1)C(=O)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G17 compound treatment 54320.0 5670.0 0.33 34920.0 -8380.0 -0.63 -0.2165 -0.303 3209130 TimTec1_003669 Nc1nc(CSc2nnc(c3cccnc3)n2CC=C)nc(n1)N4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G18 compound treatment 13840.0 -34800.0 -2.02 18080.0 -25200.0 -1.91 -2.7762 -0.9996 1317072 TimTec1_003670 Cn1c(=S)n(CCSc2nc3ccccc3[nH]2)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G19 compound treatment 27760.0 -20900.0 -1.21 31880.0 -11400.0 -0.86 -1.4673 -0.9864 3209131 TimTec1_003671 O=C1Nc2ccccc2Oc3cc(Sc4ccccc4)ccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G20 compound treatment 47160.0 -1490.0 -0.09 38800.0 -4500.0 -0.34 -0.3021 -0.8594 3084712 TimTec1_003672 CCn1c(C)nnc1SCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G21 compound treatment 46480.0 -2170.0 -0.13 43880.0 579.0 0.04 -0.0581 -0.4355 1214067 TimTec1_003673 COc1ccc(cc1)C2CC(O)CC(c3ccc(OC)cc3)C24C(=O)NC(=O)NC4=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G22 compound treatment 20640.0 -28000.0 -1.62 14080.0 -29200.0 -2.21 -2.7117 -0.9884 3084713 TimTec1_003674 CC1(C)Cc2ccccc2C(=N1)CSc3nc(c4CCCCc4n3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G23 mock treatment 52120.0 3470.0 0.2 37920.0 -5380.0 -0.41 -0.146 -0.3215 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 G24 mock treatment 50320.0 1670.0 0.1 44120.0 819.0 0.06 0.1121 0.977 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H01 compound treatment 54760.0 6110.0 0.35 38400.0 -4900.0 -0.37 -0.0122 -0.0237 1713697 TimTec1_003675 Cc1oc(cc1C(=O)N2CCCC2C(=O)O)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H02 compound treatment 27080.0 -21600.0 -1.25 22760.0 -20500.0 -1.55 -1.9833 -0.9941 3209132 TimTec1_003676 COc1ccc(cc1OC)c2cc(nc(SC3CC(O)C4OCC3O4)n2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H03 compound treatment 23400.0 -25300.0 -1.46 14880.0 -28400.0 -2.15 -2.5558 -0.9824 3084714 TimTec1_003677 CCN1C(=O)/C(=C\c2ccc(cc2Cl)N(C)C)/OC1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H04 compound treatment 44520.0 -4130.0 -0.24 28760.0 -14500.0 -1.1 -0.9477 -0.8413 1418481 TimTec1_003678 CC(C)C1NC(=O)N(C1=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H05 compound treatment 33120.0 -15500.0 -0.9 22160.0 -21100.0 -1.6 -1.768 -0.9629 3209133 TimTec1_003679 COC(=O)c1ccn(n1)C(=O)c2ccnn2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H06 compound treatment 35560.0 -13100.0 -0.76 29640.0 -13700.0 -1.03 -1.2676 -0.9884 1349643 TimTec1_003680 CCCNS(=O)(=O)c1nc2nc(C)cc(C)n2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H07 compound treatment 40400.0 -8250.0 -0.48 31480.0 -11800.0 -0.89 -0.9709 -0.9569 3209134 TimTec1_003681 Cc1cc(=O)oc2c3/C(=C/c4ccccc4)/C(=O)Oc3ccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H08 compound treatment 6000.0 -42700.0 -2.47 7120.0 -36200.0 -2.74 -3.684 -0.9987 3209135 TimTec1_003682 CSc1cccc(NC(=O)c2ccc(CN3CCOCC3)cc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H09 compound treatment 4800.0 -43900.0 -2.54 5120.0 -38200.0 -2.89 -3.8402 -0.9979 1565759 TimTec1_003683 COc1ccccc1CNc2ccc3n(cnc3c2)c4ccccc4OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H10 compound treatment 6360.0 -42300.0 -2.45 10720.0 -32600.0 -2.47 -3.4766 -1.0 3209136 TimTec1_003684 O=C1NC(=O)/C(=C/c2cn(Cc3ccccc3C#N)c4ccccc24)/N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H11 compound treatment 32160.0 -16500.0 -0.96 35760.0 -7540.0 -0.57 -1.0794 -0.9697 1298968 TimTec1_003685 CCOc1ccccc1C2C(C#N)C(=O)NC(=C2C#N)SCC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H12 compound treatment 33600.0 -15100.0 -0.87 29680.0 -13600.0 -1.03 -1.3458 -0.9965 1242991 TimTec1_003686 O=C(N1CCCC1)c2ccccc2NS(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H13 compound treatment 26440.0 -22200.0 -1.29 24640.0 -18700.0 -1.41 -1.9089 -0.9989 1005358 TimTec1_003687 O=C(CC(C#N)c1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H14 compound treatment 22320.0 -26300.0 -1.53 16520.0 -26800.0 -2.03 -2.5123 -0.9902 3209137 TimTec1_003688 COC(=O)c1c(NC(=O)/C=C/c2ccccc2)sc3CCCCc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H15 compound treatment 35000.0 -13700.0 -0.79 28240.0 -15100.0 -1.14 -1.3655 -0.9841 1564252 TimTec1_003689 CCc1ccc(cc1)N2C(=O)c3ccccc3NC2(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H16 compound treatment 40360.0 -8290.0 -0.48 40040.0 -3260.0 -0.25 -0.5143 -0.9521 1096919 TimTec1_003690 CN1C(=O)C(O)(CC(=O)c2ccccc2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H17 compound treatment 42600.0 -6050.0 -0.35 44040.0 739.0 0.06 -0.2085 -0.587 1339640 TimTec1_003691 Cc1cccc(C)c1NC(=O)C2(CCCCC2)N(Cc3ccco3)C(=O)Cc4nc(N)n[nH]4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H18 compound treatment 57040.0 8390.0 0.49 49960.0 6660.0 0.5 0.7 0.9998 3084715 TimTec1_003692 Cc1ccc(cc1)C(=O)N/C(=C\c2cn(nc2c3ccccc3)c4ccccc4)/C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H19 compound treatment 54160.0 5510.0 0.32 47680.0 4380.0 0.33 0.4599 0.9998 1493856 TimTec1_003693 Oc1cc(n[nH]1)C2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H20 compound treatment 50320.0 1670.0 0.1 41960.0 -1340.0 -0.1 -0.0035 -0.0252 3084716 TimTec1_003694 Cc1ccc(CSc2ncnn2Cc3ccc(C)cc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H21 compound treatment 38080.0 -10600.0 -0.61 27680.0 -15600.0 -1.18 -1.2693 -0.9531 1254494 TimTec1_003695 COc1ccc(cc1)c2csc(n2)N3CCCC3C(=O)OCc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H22 compound treatment 33000.0 -15700.0 -0.91 11440.0 -31900.0 -2.41 -2.3466 -0.9107 1446415 TimTec1_003696 COc1ccc(Cn2cc(nn2)c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H23 mock treatment 54040.0 5390.0 0.31 48720.0 5420.0 0.41 0.5107 0.9909 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 H24 mock treatment 53480.0 4830.0 0.28 40560.0 -2740.0 -0.21 0.051 0.1465 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I01 compound treatment 1480.0 -47200.0 -2.73 1360.0 -41900.0 -3.17 -4.1775 -0.9972 1413623 TimTec1_003697 COC(=O)COc1ccc(CSc2nc3ccccc3c(=O)n2C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I02 compound treatment 32920.0 -15700.0 -0.91 35800.0 -7500.0 -0.57 -1.0461 -0.974 1057656 TimTec1_003698 Nc1ncnc2n(cnc12)C3OC(CO)C=C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I03 compound treatment 14880.0 -33800.0 -1.96 23600.0 -19700.0 -1.49 -2.4381 -0.991 3084720 TimTec1_003699 Cc1ccc(Nc2nc(C)cc(C)n2)c(Br)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I04 compound treatment 1760.0 -46900.0 -2.72 1880.0 -41400.0 -3.14 -4.1382 -0.9975 3209257 TimTec1_003700 Nc1cc(c2ccccc2)c3ccccc3n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I05 compound treatment 26760.0 -21900.0 -1.27 23440.0 -19900.0 -1.5 -1.96 -0.9964 1406532 TimTec1_003701 Fc1ccccc1n2nnnc2SCC(=O)N3c4ccccc4Sc5ccc(Cl)cc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I06 compound treatment 28320.0 -20300.0 -1.18 23720.0 -19600.0 -1.48 -1.8811 -0.9935 3084723 TimTec1_003702 CN1C(=O)C(=CNCc2ccc3OCOc3c2)C(=O)N(C)C1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I07 compound treatment 2480.0 -46200.0 -2.68 2240.0 -41100.0 -3.11 -4.0894 -0.9972 3209258 TimTec1_003703 COc1ccc(/C=c\2/[nH]\c(=C\C(=O)c3ccccc3)\c(=O)[nH]c2=O)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I08 compound treatment 30280.0 -18400.0 -1.06 32240.0 -11100.0 -0.84 -1.3448 -0.9929 1466355 TimTec1_003704 COc1ccc(Cl)cc1C(=O)Nc2ccc(NC(=O)c3ccco3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I09 compound treatment 44080.0 -4570.0 -0.26 35840.0 -7460.0 -0.56 -0.5867 -0.9405 3209259 TimTec1_003705 OC(=O)C1CSC(N1C(=O)c2ccccc2F)c3ccccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I10 compound treatment 27640.0 -21000.0 -1.22 28000.0 -15300.0 -1.16 -1.6799 -0.9997 1721830 TimTec1_003706 COC(=O)CC1=C(C)C(=O)CC2C(C)(C)CCC[C@@]21C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I11 compound treatment 34960.0 -13700.0 -0.79 36640.0 -6660.0 -0.5 -0.9175 -0.9761 3209260 TimTec1_003707 FC(F)(F)c1nnc(NC(=O)CN2C(=O)C3C4CC(C=C4)C3C2=O)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I12 compound treatment 33560.0 -15100.0 -0.87 33520.0 -9780.0 -0.74 -1.1419 -0.9966 3084757 TimTec1_003708 CN(C)C(=O)Cn1c(=O)oc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I13 compound treatment 16120.0 -32500.0 -1.88 19680.0 -23600.0 -1.79 -2.5972 -0.9997 3084758 TimTec1_003709 O=C(CSc1nc2ccccc2o1)NCCOC3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I14 compound treatment 14040.0 -34600.0 -2.01 14680.0 -28600.0 -2.17 -2.95 -0.9993 1684184 TimTec1_003710 COc1ccc(cc1OC)C(O)c2nccn2Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I15 compound treatment 5000.0 -43700.0 -2.53 10200.0 -33100.0 -2.51 -3.5601 -1.0 3209261 TimTec1_003711 CCCc1c(C#N)c(N)nc(SCCCN2CCN(CC2)c3cccc(Cl)c3)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I16 compound treatment 23000.0 -25700.0 -1.49 22640.0 -20700.0 -1.56 -2.1569 -0.9997 3084761 TimTec1_003712 NC(=S)N1N=C(CC1c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I17 compound treatment 30400.0 -18300.0 -1.06 31840.0 -11500.0 -0.87 -1.3613 -0.9952 3209262 TimTec1_003713 O=C(Nc1ccccc1)/N=c\2/[nH]c(=O)c3ccccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I18 compound treatment 54960.0 6310.0 0.37 41000.0 -2300.0 -0.17 0.1352 0.334 1743320 TimTec1_003714 CC1CC(NCc2ccccc2)N(N1c3ccccc3)C(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I19 compound treatment 51200.0 2550.0 0.15 41120.0 -2180.0 -0.17 -0.0124 -0.0562 3209263 TimTec1_003715 NC(=O)CC1=NC(=O)CS1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I20 compound treatment 48440.0 -214.0 -0.01 35560.0 -7740.0 -0.59 -0.4231 -0.7219 1279387 TimTec1_003716 CC(=O)Nc1cccc(c1O)c2cc(=O)c3ccccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I21 compound treatment 39400.0 -9250.0 -0.54 26960.0 -16300.0 -1.24 -1.2538 -0.93 3084764 TimTec1_003717 CC1(C)COC(=N1)/C=C(\N)/c2ccc(Br)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I22 compound treatment 16520.0 -32100.0 -1.86 12160.0 -31100.0 -2.36 -2.9833 -0.9932 1589286 TimTec1_003718 Clc1ccc(cc1)S(=O)(=O)c2cccc(c2)S(=O)(=O)N3CCC(=O)C4CCCCC43 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I23 mock treatment 46960.0 -1690.0 -0.1 48640.0 5340.0 0.4 0.2164 0.5203 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 I24 mock treatment 50320.0 1670.0 0.1 47680.0 4380.0 0.33 0.3026 0.8766 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J01 compound treatment 44760.0 -3890.0 -0.23 37840.0 -5460.0 -0.41 -0.4518 -0.9594 1383518 TimTec1_003719 Cc1nc(Oc2ccc(Cl)cc2)c(C(=O)O)c(C)c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J02 compound treatment 1480.0 -47200.0 -2.73 1680.0 -41600.0 -3.15 -4.1604 -0.9975 1251766 TimTec1_003720 COc1ccc(OC)c(Nc2nc(cs2)c3c(C)nc4sccn34)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J03 compound treatment 47080.0 -1570.0 -0.09 34360.0 -8940.0 -0.68 -0.543 -0.7952 3084768 TimTec1_003721 CCN/1C(=O)CS\C1=N/N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J04 compound treatment 41200.0 -7450.0 -0.43 32000.0 -11300.0 -0.86 -0.9103 -0.9499 3209264 TimTec1_003722 CC(C)CC1NC(=O)N(C1=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J05 compound treatment 22040.0 -26600.0 -1.54 22560.0 -20700.0 -1.57 -2.2005 -1.0 3084770 TimTec1_003723 FC(F)(F)C(=O)Nc1ccc2nn(nc2c1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J06 compound treatment 39280.0 -9370.0 -0.54 32000.0 -11300.0 -0.86 -0.9889 -0.976 3209265 TimTec1_003724 Oc1ccccc1N2CCCC2=N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J07 compound treatment 23960.0 -24700.0 -1.43 26960.0 -16300.0 -1.24 -1.8863 -0.9974 3084773 TimTec1_003725 Nc1cc(ccc1Sc2nc3ccccc3s2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J08 compound treatment 62480.0 13800.0 0.8 46960.0 3660.0 0.28 0.7623 0.8993 3209266 TimTec1_003726 O=C(CCSc1ccccc1)NCc2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J09 compound treatment 40480.0 -8170.0 -0.47 38040.0 -5260.0 -0.4 -0.6165 -0.9963 1504517 TimTec1_003727 COc1cc(ccc1O)C(=O)OC2CC3CCC(C2)N3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J10 compound treatment 9280.0 -39400.0 -2.28 9560.0 -33700.0 -2.55 -3.419 -0.9984 3084774 TimTec1_003728 CCOC(=O)CN1C(=O)S/C(=C\c2ccccc2OCc3ccccc3F)/C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J11 compound treatment 21560.0 -27100.0 -1.57 25000.0 -18300.0 -1.39 -2.0895 -0.9981 1209465 TimTec1_003729 NC(=O)c1oc2ccccc2c1NC(=O)CSc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J12 compound treatment 32760.0 -15900.0 -0.92 34640.0 -8660.0 -0.66 -1.1147 -0.9861 3084776 TimTec1_003730 CCOC(=O)C1=C(C)N/C(=C/c2ccccc2)/C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J13 compound treatment 25840.0 -22800.0 -1.32 28680.0 -14600.0 -1.11 -1.7172 -0.9961 1488603 TimTec1_003731 CSC1=C(C#N)C(C2=C(CCCC2=O)N1)c3ccccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J14 compound treatment 24720.0 -23900.0 -1.39 31720.0 -11600.0 -0.88 -1.6004 -0.9755 3084778 TimTec1_003732 CN(Cc1ccccc1)C(=O)c2ccccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J15 compound treatment 38960.0 -9690.0 -0.56 34400.0 -8900.0 -0.67 -0.8736 -0.9959 1610985 TimTec1_003733 Cn1cnnc1c2cccc(NC(=O)C(c3ccccc3)c4ccccc4)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J16 compound treatment 1960.0 -46700.0 -2.71 1720.0 -41600.0 -3.15 -4.1386 -0.9972 1385134 TimTec1_003734 COc1cc(ccc1OCc2ccc(Cl)cc2)C(=O)NCc3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J17 compound treatment 21400.0 -27300.0 -1.58 17640.0 -25700.0 -1.94 -2.49 -0.9947 1566664 TimTec1_003735 Nc1nonc1c2nc3ccccc3n2Cc4ccc(F)cc4Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J18 compound treatment 51560.0 2910.0 0.17 37160.0 -6140.0 -0.46 -0.2096 -0.424 3209267 TimTec1_003736 O=C(NC1CCS(=O)(=O)C1)/C(=C/c2ccccc2)/NC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J19 compound treatment 30080.0 -18600.0 -1.08 29520.0 -13800.0 -1.04 -1.4986 -0.9999 1711733 TimTec1_003737 Cn1c(S)nnc1COc2ccc(cc2)C(C)(C)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J20 compound treatment 42720.0 -5930.0 -0.34 26480.0 -16800.0 -1.27 -1.1434 -0.867 1660155 TimTec1_003738 CC(Oc1ccc2c3CCCc3c(=O)oc2c1)C(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J21 compound treatment 12800.0 -35900.0 -2.08 8200.0 -35100.0 -2.66 -3.3476 -0.9926 1699825 TimTec1_003739 COc1cccc(c1)C(=O)NCC2(CCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J22 compound treatment 48440.0 -214.0 -0.01 39560.0 -3740.0 -0.28 -0.209 -0.7373 1582857 TimTec1_003740 Oc1c(c2ccn(n2)c3ccccc3)c(=O)n(c4ccccc4)c5ccccc15 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J23 mock treatment 44880.0 -3770.0 -0.22 41600.0 -1700.0 -0.13 -0.2457 -0.9681 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 J24 mock treatment 49600.0 946.0 0.05 42720.0 -581.0 -0.04 0.0077 0.1089 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K01 compound treatment 46000.0 -2650.0 -0.15 29960.0 -13300.0 -1.01 -0.8228 -0.8055 1297374 TimTec1_003741 OC(=O)c1ccc(CSc2nnnn2C3CCCCC3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K02 compound treatment 40600.0 -8050.0 -0.47 25520.0 -17800.0 -1.35 -1.2817 -0.8997 1280009 TimTec1_003742 Brc1ccccc1C(CC(=O)c2ccccc2)C3C(=O)NC(=O)NC3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K03 compound treatment 39880.0 -8770.0 -0.51 21960.0 -21300.0 -1.62 -1.5017 -0.8867 3084823 TimTec1_003743 CCC(=C1C(=O)NC(=O)NC1=O)Nc2ccccc2N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K04 compound treatment 18720.0 -29900.0 -1.73 14480.0 -28800.0 -2.18 -2.769 -0.9935 3209268 TimTec1_003744 Cc1ccc(cc1)c2cc(O)nc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K05 compound treatment 26880.0 -21800.0 -1.26 21040.0 -22300.0 -1.69 -2.0835 -0.9898 3209269 TimTec1_003745 O=c1[nH]c(=S)c2CCCc2n1N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K06 compound treatment 30920.0 -17700.0 -1.03 24360.0 -18900.0 -1.43 -1.7403 -0.9866 1426461 TimTec1_003746 CS(=O)(=O)N(CCC#N)Cc1ccco1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K07 compound treatment 45280.0 -3370.0 -0.2 35360.0 -7940.0 -0.6 -0.5633 -0.8911 1414086 TimTec1_003747 COc1cccc(c1)C2N(C(=O)C(=C2C(=O)c3ccc(Cl)cc3)O)c4ccc(OCC(=O)O)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K08 compound treatment 35840.0 -12800.0 -0.74 31960.0 -11300.0 -0.86 -1.132 -0.9974 1107242 TimTec1_003748 O=S(=O)(Nc1cccnc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K09 compound treatment 8840.0 -39800.0 -2.31 10720.0 -32600.0 -2.47 -3.375 -0.9994 1611751 TimTec1_003749 CCOC(=O)c1ccc(cc1)N2C(C(Oc3ccccc3)C2=O)c4ccc(OCC)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K10 compound treatment 23400.0 -25300.0 -1.46 26240.0 -17100.0 -1.29 -1.9478 -0.9981 3084827 TimTec1_003750 Cc1c(N=C2c3ccccc3-c4ccccc24)c(=O)n(c5ccccc5)n1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K11 compound treatment 16200.0 -32500.0 -1.88 17840.0 -25500.0 -1.93 -2.6924 -0.9999 1139869 TimTec1_003751 CCOC(=O)C1=C(NC(=O)C(C#N)C21CCCCC2)SCC(=O)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K12 compound treatment 28000.0 -20700.0 -1.2 28520.0 -14800.0 -1.12 -1.6373 -0.9994 3084829 TimTec1_003752 CC(NC(=O)Oc1c(Cl)cc(Cl)c2ccccc12)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K13 compound treatment 1560.0 -47100.0 -2.73 1560.0 -41700.0 -3.16 -4.1635 -0.9973 1248629 TimTec1_003753 CC1(C)CC(C)(c2ccccc2)c3ccccc3N1C(=O)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K14 compound treatment 37600.0 -11100.0 -0.64 35000.0 -8300.0 -0.63 -0.8972 -1.0 1738055 TimTec1_003754 NS(=O)(=O)c1ccccc1C(=O)N2CCN(CC2)C(=O)c3ccccc3S(=O)(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K15 compound treatment 22440.0 -26200.0 -1.52 24360.0 -18900.0 -1.43 -2.0877 -0.9996 3211496 TimTec1_003755 Fc1ccc(NC(=O)CS(=O)(=O)c2ccc(cc2Cl)C(F)(F)F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K16 compound treatment 31840.0 -16800.0 -0.97 24360.0 -18900.0 -1.43 -1.7026 -0.9823 3084832 TimTec1_003756 CCOC(=O)Nc1cccc2nsnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K17 compound treatment 6000.0 -42700.0 -2.47 1200.0 -42100.0 -3.19 -4.0009 -0.9921 3211497 TimTec1_003757 CCCCC(CC)CSc1nc2cccnc2[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K18 compound treatment 15480.0 -33200.0 -1.92 12160.0 -31100.0 -2.36 -3.0259 -0.9949 3211498 TimTec1_003758 Clc1ccc(Cl)c(c1)S(=O)(=O)NCCOC2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K19 compound treatment 32840.0 -15800.0 -0.92 23640.0 -19700.0 -1.49 -1.7002 -0.9728 3084834 TimTec1_003759 NC(=O)Oc1cccc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K20 compound treatment 23960.0 -24700.0 -1.43 25160.0 -18100.0 -1.37 -1.9826 -0.9998 1510460 TimTec1_003760 Fc1ccc(CC2Sc3nc4ccccc4n3C2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K21 compound treatment 39400.0 -9250.0 -0.54 40080.0 -3220.0 -0.24 -0.5515 -0.9364 3084866 TimTec1_003761 Cc1ccc(cc1)C(F)(F)C(F)(F)c2ccccc2c3nn[nH]n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K22 compound treatment 40240.0 -8410.0 -0.49 38920.0 -4380.0 -0.33 -0.5792 -0.9824 3211499 TimTec1_003762 Cn1nnc(n1)N2C(C(=C(O)C2=O)C(=O)c3ccco3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K23 mock treatment 38520.0 -10100.0 -0.59 30960.0 -12300.0 -0.93 -1.0757 -0.975 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 K24 mock treatment 38400.0 -10300.0 -0.59 32560.0 -10700.0 -0.81 -0.995 -0.9881 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L01 compound treatment 40880.0 -7770.0 -0.45 27080.0 -16200.0 -1.23 -1.1867 -0.9074 3211500 TimTec1_003763 O=C(N/C(=C/c1ccccc1)/C(=O)N2CCc3ccccc3C2)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L02 compound treatment 24320.0 -24300.0 -1.41 17600.0 -25700.0 -1.95 -2.3725 -0.9875 1595878 TimTec1_003764 CC(C)c1ccc(cc1)S(=O)(=O)N2CCN(C(C)C2)S(=O)(=O)c3ccc(cc3)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L03 compound treatment 44000.0 -4650.0 -0.27 32360.0 -10900.0 -0.83 -0.7763 -0.8913 1381352 TimTec1_003765 NC(=O)CCNC1(CC2CC3CC(C2)C1)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L04 compound treatment 22120.0 -26500.0 -1.54 20320.0 -23000.0 -1.74 -2.3171 -0.9981 3084870 TimTec1_003766 COc1ccc(C(OC(=O)C)C#N)c(OCc2ccccc2)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L05 compound treatment 31440.0 -17200.0 -1.0 23440.0 -19900.0 -1.5 -1.7683 -0.9801 3211501 TimTec1_003767 Cc1cc(=O)oc2c3C(=O)/C(=C/c4ccc(Cl)cc4)/Oc3ccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L06 compound treatment 45960.0 -2690.0 -0.16 39280.0 -4020.0 -0.3 -0.3256 -0.9518 1452130 TimTec1_003768 CC1(C)CC(CC(C)(C)N1O)NS(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L07 compound treatment 16440.0 -32200.0 -1.87 14560.0 -28700.0 -2.18 -2.8581 -0.9971 3211502 TimTec1_003769 CCn1c2nc(cn2c3ccccc13)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L08 compound treatment 59360.0 10700.0 0.62 54400.0 11100.0 0.84 1.0327 0.9889 3084873 TimTec1_003770 O=C(CCSc1ccccc1)NC2CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L09 compound treatment 43440.0 -5210.0 -0.3 37480.0 -5820.0 -0.44 -0.5252 -0.983 1521475 TimTec1_003771 CCc1c(nnn1c2nonc2N)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L10 compound treatment 9120.0 -39500.0 -2.29 6680.0 -36600.0 -2.77 -3.5797 -0.9955 3211503 TimTec1_003772 Cc1cc(ccc1/C=C(/C#N)\c2ccc(F)cc2)N3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L11 compound treatment 16880.0 -31800.0 -1.84 18680.0 -24600.0 -1.86 -2.6195 -1.0 1396173 TimTec1_003773 NC(=O)CSC1=C(C#N)C(C(=C(N)N1)C#N)c2ccccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L12 compound treatment 21240.0 -27400.0 -1.59 24800.0 -18500.0 -1.4 -2.1134 -0.998 3211504 TimTec1_003774 COC(=O)C/1=C(C)NC(=O)\C1=C/c2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L13 compound treatment 42920.0 -5730.0 -0.33 41760.0 -1540.0 -0.12 -0.3174 -0.9015 3211505 TimTec1_003775 Cc1oc(cc1C(=O)Nc2cccc(/C=C\C(=O)O)c2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L14 compound treatment 40160.0 -8490.0 -0.49 34440.0 -8860.0 -0.67 -0.8223 -0.9884 3084877 TimTec1_003776 Clc1ccc(C(=O)NC2CC2)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L15 compound treatment 52400.0 3750.0 0.22 46160.0 2860.0 0.22 0.3065 1.0 1596451 TimTec1_003777 Cc1oc(cc1C(=O)NCc2ccc(o2)C(=O)O)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L16 compound treatment 47160.0 -1490.0 -0.09 38840.0 -4460.0 -0.34 -0.3 -0.8605 1551836 TimTec1_003778 CC1=C(C(C(=C(C)N1)C(=O)N)c2ccco2)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L17 compound treatment 47200.0 -1450.0 -0.08 36080.0 -7220.0 -0.55 -0.4461 -0.8065 1181188 TimTec1_003779 CSc1ccccc1C(=O)Nc2cccc(c2)C(C)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L18 compound treatment 55840.0 7190.0 0.42 37960.0 -5340.0 -0.4 0.0085 0.0147 1050401 TimTec1_003780 OC(COc1ccccc1)CN2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L19 compound treatment 30760.0 -17900.0 -1.04 26200.0 -17100.0 -1.29 -1.6484 -0.9939 1378484 TimTec1_003781 Cc1ccc(OCC(=O)Nc2ccc(cc2)N3CCOCC3)c(c1)n4nc5ccccc5n4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L20 compound treatment 46440.0 -2210.0 -0.13 42480.0 -821.0 -0.06 -0.1346 -0.9447 1477400 TimTec1_003782 CC1CN(CC(C)O1)C(=O)c2cc3ccccc3oc2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L21 compound treatment 49080.0 426.0 0.02 44160.0 859.0 0.07 0.0634 0.9121 1507564 TimTec1_003783 COC(=O)c1ccccc1NC(=O)CC2(C(=O)c3ccccc3C2=O)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L22 compound treatment 51000.0 2350.0 0.14 47560.0 4260.0 0.32 0.3241 0.9263 1451160 TimTec1_003784 Cn1c(=O)c(C(CC(=O)c2cc3ccccc3oc2=O)Nc4ccccc4)c(O)c5ccccc15 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L23 mock treatment 47960.0 -694.0 -0.04 43640.0 339.0 0.03 -0.0103 -0.2158 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 L24 mock treatment 48600.0 -53.8 0.0 39280.0 -4020.0 -0.3 -0.2174 -0.7143 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M01 compound treatment 45560.0 -3090.0 -0.18 37920.0 -5380.0 -0.41 -0.4148 -0.932 1644138 TimTec1_003785 COC(=O)C1OC2(CCCC2)OC1C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M02 compound treatment 56080.0 7430.0 0.43 29880.0 -13400.0 -1.02 -0.4141 -0.3754 1168609 TimTec1_003786 O=C(CC(C1C(=O)NC(=O)NC1=O)c2ccccc2)C3CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M03 compound treatment 35480.0 -13200.0 -0.76 24440.0 -18900.0 -1.43 -1.5492 -0.957 3084947 TimTec1_003787 CCOC1=NC(N=C2Sc3ccccc3N21)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M04 compound treatment 20160.0 -28500.0 -1.65 16680.0 -26600.0 -2.02 -2.5922 -0.9951 3211506 TimTec1_003788 Nc1nc2ccc(Cl)cc2c(c1CN3CCOCC3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M05 compound treatment 18160.0 -30500.0 -1.77 14760.0 -28500.0 -2.16 -2.7769 -0.995 1277239 TimTec1_003789 COc1cc(OC)cc(c1)C(=O)c2ccc(cc2)C(=O)NC3(CC3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M06 compound treatment 43760.0 -4890.0 -0.28 31880.0 -11400.0 -0.86 -0.8118 -0.8923 3084948 TimTec1_003790 OC(=O)Cn1cc(C=C2C(=O)NC(=O)NC2=O)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M07 compound treatment 41560.0 -7090.0 -0.41 40400.0 -2900.0 -0.22 -0.4459 -0.9569 1682965 TimTec1_003791 OC1=C(C(N(C1=O)c2ccccn2)c3ccccc3)C(=O)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M08 compound treatment 24240.0 -24400.0 -1.41 17600.0 -25700.0 -1.95 -2.3758 -0.9877 3084949 TimTec1_003792 Cc1sc(N)c(C#N)c1c2ccc(Cl)cc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M09 compound treatment 27840.0 -20800.0 -1.21 27200.0 -16100.0 -1.22 -1.7145 -1.0 3211507 TimTec1_003793 CCN(Cc1ccccc1)S(=O)(=O)c2nc3nc(C)c(C)c(C)n3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M10 compound treatment 4120.0 -44500.0 -2.58 4560.0 -38700.0 -2.93 -3.8981 -0.998 3084950 TimTec1_003794 Cc1cc(C)nc(N/C(=N/Cc2ccccc2Cl)/N)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M11 compound treatment 14360.0 -34300.0 -1.99 12520.0 -30800.0 -2.33 -3.0525 -0.9969 1289426 TimTec1_003795 CCCOc1c(cnc2ccccc12)c3ccc4ccccc4n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M12 compound treatment 20240.0 -28400.0 -1.65 15760.0 -27500.0 -2.08 -2.6382 -0.9932 3084951 TimTec1_003796 OC1(CC(=NN1)/C=C/c2cccs2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M13 compound treatment 42480.0 -6170.0 -0.36 37800.0 -5500.0 -0.42 -0.5474 -0.9971 1348823 TimTec1_003797 CCNC1(CCC1)c2cccc(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M14 compound treatment 46480.0 -2170.0 -0.13 39120.0 -4180.0 -0.32 -0.3129 -0.9184 3211508 TimTec1_003798 CC1=NN(C(=O)CSc2nnc(o2)c3ccncc3)C(C)(O)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M15 compound treatment 42960.0 -5690.0 -0.33 37280.0 -6020.0 -0.46 -0.5555 -0.9874 1588714 TimTec1_003799 CCOc1ccc(CC2C(=O)NC(=O)N(Cc3ccccc3)C2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M16 compound treatment 29360.0 -19300.0 -1.12 27520.0 -15800.0 -1.19 -1.6351 -0.9995 1383650 TimTec1_003800 O=C(Nc1ccc2NS(=O)(=O)c3cccc1c23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M17 compound treatment 20080.0 -28600.0 -1.66 13200.0 -30100.0 -2.28 -2.7818 -0.9877 3211509 TimTec1_003801 CCN(CC)C(=S)SC1CC(=O)N(C1=O)c2ccc(cc2)S(=O)(=O)NC(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M18 compound treatment 43880.0 -4770.0 -0.28 33400.0 -9900.0 -0.75 -0.7255 -0.9082 1533734 TimTec1_003802 CC1=C(C(=O)Nc2ccccc2)C3(CCCCC3)C(=C(N1)SCC(=O)Nc4nccs4)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M19 compound treatment 20720.0 -27900.0 -1.62 19880.0 -23400.0 -1.77 -2.398 -0.999 3211595 TimTec1_003803 COc1ccc(cc1)C2=CC(SC(=N)N2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M20 compound treatment 48280.0 -374.0 -0.02 42880.0 -421.0 -0.03 -0.0379 -0.9822 1699056 TimTec1_003804 CN(C1CC(C)(C)N(C)C(C)(C)C1)C(=O)c2cc[nH]n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M21 compound treatment 51040.0 2390.0 0.14 44760.0 1460.0 0.11 0.1758 0.9938 1491671 TimTec1_003805 Nc1nc(N)c2sc(NCC=C)c(C#N)c2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M22 compound treatment 5480.0 -43200.0 -2.5 1960.0 -41300.0 -3.13 -3.9815 -0.9938 3211596 TimTec1_003806 Fc1ccc(/C=c\2/[nH]\c(=C\C(=O)c3ccccc3)\c(=O)[nH]c2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M23 mock treatment 46240.0 -2410.0 -0.14 40040.0 -3260.0 -0.25 -0.2734 -0.9638 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 M24 mock treatment 44320.0 -4330.0 -0.25 40960.0 -2340.0 -0.18 -0.3029 -0.9855 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N01 compound treatment 35440.0 -13200.0 -0.77 25000.0 -18300.0 -1.39 -1.5209 -0.9609 3084958 TimTec1_003807 COc1nc(NC2CC2)nc(Nc3ccc(OC(F)(F)F)cc3)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N02 compound treatment 43280.0 -5370.0 -0.31 31280.0 -12000.0 -0.91 -0.8636 -0.8979 1476683 TimTec1_003808 OC(=O)c1cc(ccc1O)S(=O)(=O)Nc2ccc(O)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N03 compound treatment 26840.0 -21800.0 -1.26 15280.0 -28000.0 -2.12 -2.3935 -0.9694 3084960 TimTec1_003809 CCOC(=O)/C(=c\1/s\c(=C\2/C=Cc3ccccc3N2CC)\c(=O)n1CC)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N04 compound treatment 18920.0 -29700.0 -1.72 12920.0 -30400.0 -2.3 -2.8443 -0.9899 1006588 TimTec1_003810 N#CC(c1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N05 compound treatment 28000.0 -20700.0 -1.2 27800.0 -15500.0 -1.17 -1.6758 -1.0 1698122 TimTec1_003811 CCSC1=C(C#N)C(C(=C(C)N1)C(=O)OC(C)(C)C)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N06 compound treatment 33720.0 -14900.0 -0.87 35760.0 -7540.0 -0.57 -1.0154 -0.9796 3084962 TimTec1_003812 CCc1ccc(cc1)C2C(=CNC=C2C(=O)OC)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N07 compound treatment 38960.0 -9690.0 -0.56 36440.0 -6860.0 -0.52 -0.7644 -0.9992 1644445 TimTec1_003813 CCOC(=O)C1=C(C)N(CCO)C(=O)NC1c2ccc(O)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N08 compound treatment 34120.0 -14500.0 -0.84 32000.0 -11300.0 -0.86 -1.2003 -1.0 3084964 TimTec1_003814 Cc1cc(/C=N/n2cnnc2)c(C)n1c3ccc(cc3)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N09 compound treatment 37360.0 -11300.0 -0.65 39400.0 -3900.0 -0.3 -0.6715 -0.9354 3211597 TimTec1_003815 Cc1nnc(SCC(=O)O)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N10 compound treatment 10360.0 -38300.0 -2.22 9880.0 -33400.0 -2.53 -3.3577 -0.9979 3211598 TimTec1_003816 Fc1ccc(/N=C\2/NC(=O)/C(=C\c3ccc(o3)N4CCCC4)/S2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N11 compound treatment 7640.0 -41000.0 -2.38 7120.0 -36200.0 -2.74 -3.6168 -0.9975 1466268 TimTec1_003817 NC1=C(C#N)C(C(=C(N1)SCc2ccccc2)C#N)c3ccccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N12 compound treatment 31280.0 -17400.0 -1.01 32760.0 -10500.0 -0.8 -1.276 -0.9934 3085029 TimTec1_003818 CCOC(=O)N1CCN(CC1)C(=O)CN(C2CCCCC2)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N13 compound treatment 10680.0 -38000.0 -2.2 4800.0 -38500.0 -2.91 -3.6165 -0.9904 3211599 TimTec1_003819 Nc1nc(SCC(=O)c2ccc3ccccc3c2)c(C#N)c(c1C#N)c4cccc(F)c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N14 compound treatment 29600.0 -19100.0 -1.1 20880.0 -22400.0 -1.7 -1.9807 -0.9783 3085032 TimTec1_003820 Brc1ccc(cc1)C(=O)NCCSc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N15 compound treatment 38320.0 -10300.0 -0.6 30680.0 -12600.0 -0.96 -1.0989 -0.9747 1677707 TimTec1_003821 O=C(CC(C(=O)c1ccccc1)c2ccccc2)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N16 compound treatment 31200.0 -17500.0 -1.01 19960.0 -23300.0 -1.77 -1.9644 -0.9649 3085034 TimTec1_003822 COc1ccccc1OCCSc2nc3ccccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N17 compound treatment 43400.0 -5250.0 -0.3 34760.0 -8540.0 -0.65 -0.6724 -0.9409 1302141 TimTec1_003823 Clc1ccc(NC(=O)c2cc(Br)ccc2OCC(=O)NC3CC3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N18 compound treatment 52840.0 4190.0 0.24 31160.0 -12100.0 -0.92 -0.4783 -0.5033 1645048 TimTec1_003824 CC(C)N1CC2(CN(CC(C1)(C2O)c3ccccc3)C(C)C)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N19 compound treatment 25800.0 -22900.0 -1.32 18960.0 -24300.0 -1.84 -2.2391 -0.9869 3085037 TimTec1_003825 COc1ccc(cc1)C(=O)/C=C\2/NCC3N(CCc4ccccc34)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N20 compound treatment 5640.0 -43000.0 -2.49 2720.0 -40600.0 -3.07 -3.9343 -0.9946 1574760 TimTec1_003826 COc1ccc(cc1)C2CC(=Nc3ccccc3N2)c4cc5ccccc5oc4=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N21 compound treatment 45600.0 -3050.0 -0.18 42120.0 -1180.0 -0.09 -0.1883 -0.95 3085038 TimTec1_003827 CC(=C)C(=O)Nc1ccc(O)cc1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N22 compound treatment 34480.0 -14200.0 -0.82 30480.0 -12800.0 -0.97 -1.2669 -0.9965 1563548 TimTec1_003828 CC1=Nc2ccccc2Sc3c1c(=O)n(c4ccccc4)c5ccccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N23 mock treatment 39720.0 -8930.0 -0.52 41200.0 -2100.0 -0.16 -0.4785 -0.8836 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 N24 mock treatment 46280.0 -2370.0 -0.14 42520.0 -781.0 -0.06 -0.1391 -0.9289 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O01 compound treatment 25720.0 -22900.0 -1.33 9280.0 -34000.0 -2.58 -2.7605 -0.9526 3085040 TimTec1_003829 CN/1CCS\C1=C/C=C/2\SC(=S)N(C)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O02 compound treatment 50360.0 1710.0 0.1 43160.0 -141.0 -0.01 0.0623 0.627 1348649 TimTec1_003830 Oc1c(c2ccon2)c(=O)n(c3ccccc3)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O03 compound treatment 49400.0 746.0 0.04 42160.0 -1140.0 -0.09 -0.0305 -0.3159 3085042 TimTec1_003831 CCc1nnc(NC(=O)c2nc[nH]n2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O04 compound treatment 24160.0 -24500.0 -1.42 19000.0 -24300.0 -1.84 -2.3042 -0.9918 1580872 TimTec1_003832 CCOC(=O)C1=NN(C(CC1=O)c2ccccc2)c3ccc(OC)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O05 compound treatment 30520.0 -18100.0 -1.05 25960.0 -17300.0 -1.31 -1.6711 -0.9939 3085044 TimTec1_003833 O=C(c1ccco1)c2cn(nc2C(=O)c3nc4ccccc4s3)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O06 compound treatment 15800.0 -32900.0 -1.9 13720.0 -29600.0 -2.24 -2.9293 -0.9967 3211600 TimTec1_003834 CCN1C(=O)C(=Cc2ccc(cc2OC)N3CCOCC3)C(=O)N(CC)C1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O07 compound treatment 39400.0 -9250.0 -0.54 42720.0 -581.0 -0.04 -0.4102 -0.7626 1409512 TimTec1_003835 COCC1=NN(C(=O)C1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O08 compound treatment 11440.0 -37200.0 -2.16 16000.0 -27300.0 -2.07 -2.9858 -0.9998 3211601 TimTec1_003836 CCCc1ccc(cc1)c2c(C)sc(N)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O09 compound treatment 20720.0 -27900.0 -1.62 20080.0 -23200.0 -1.76 -2.3873 -0.9991 3085047 TimTec1_003837 CC(C)CSc1nc(C)c(C)c(C)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O10 compound treatment 21520.0 -27100.0 -1.57 27880.0 -15400.0 -1.17 -1.937 -0.9893 1586721 TimTec1_003838 CCC1(CC)Cc2ccccc2C(=N1)CC(=O)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O11 compound treatment 36200.0 -12500.0 -0.72 41960.0 -1340.0 -0.1 -0.582 -0.7987 1726435 TimTec1_003839 Cn1c(=O)n(C)c2c(O)c([nH]c2c1=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O12 compound treatment 42800.0 -5850.0 -0.34 39680.0 -3620.0 -0.27 -0.4336 -0.9944 1470820 TimTec1_003840 CCC(=O)Nc1ccc2c(C)cc(C)nc2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O13 compound treatment 4200.0 -44500.0 -2.58 5560.0 -37700.0 -2.86 -3.8412 -0.9987 1381475 TimTec1_003841 CCCCc1nc(OCC(=O)c2ccccc2)c(C#N)c3CC(C)(C)OCc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O14 compound treatment 55000.0 6350.0 0.37 46240.0 2940.0 0.22 0.4173 0.971 1312823 TimTec1_003842 O=CNc1ncc(s1)c2nc3ccccc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O15 compound treatment 10120.0 -38500.0 -2.23 5880.0 -37400.0 -2.83 -3.5816 -0.9931 3211602 TimTec1_003843 FC(F)(F)c1n[nH]c(c1C2(CC3CC4CC(C3)C2)C4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O16 compound treatment 56960.0 8310.0 0.48 42040.0 -1260.0 -0.1 0.2728 0.556 3211603 TimTec1_003844 C/C(=N\N1C(=N)SC(CC1=O)C(=O)Nc2ccc(cc2)C(=O)O)/CCc3ccc4OCOc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O17 compound treatment 43560.0 -5090.0 -0.3 30600.0 -12700.0 -0.96 -0.8885 -0.8835 3085116 TimTec1_003845 O=C(NC1=NC(=O)CS1)N2c3ccccc3Sc4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O18 compound treatment 37560.0 -11100.0 -0.64 28080.0 -15200.0 -1.15 -1.2692 -0.962 1326791 TimTec1_003846 COc1ccc(Cl)cc1NC(=O)CN(c2ccccc2)S(=O)(=O)N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O19 compound treatment 26600.0 -22100.0 -1.28 24520.0 -18800.0 -1.42 -1.9087 -0.9986 1539349 TimTec1_003847 Cc1cccc2c(cc(=O)[nH]c12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O20 compound treatment 42880.0 -5770.0 -0.33 36520.0 -6780.0 -0.51 -0.5995 -0.9785 3211604 TimTec1_003848 CC(C)(CO)NC(=O)CSc1ccc(cc1Cl)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O21 compound treatment 40560.0 -8090.0 -0.47 32680.0 -10600.0 -0.8 -0.9001 -0.9671 1701681 TimTec1_003849 Brc1ccc(NCc2c[nH]c3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O22 compound treatment 24080.0 -24600.0 -1.42 22040.0 -21300.0 -1.61 -2.1447 -0.9981 3085119 TimTec1_003850 CN1Cc2cc(CN3C(=O)c4ccccc4C3=O)ccc2NC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O23 mock treatment 49960.0 1310.0 0.08 48480.0 5180.0 0.39 0.3307 0.8283 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 O24 mock treatment 51760.0 3110.0 0.18 40800.0 -2500.0 -0.19 -0.0066 -0.0253 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P01 compound treatment 27400.0 -21300.0 -1.23 21160.0 -22100.0 -1.68 -2.0558 -0.9885 1431065 TimTec1_003851 COc1ccc(cc1)n2cnc3cc(NCc4ccccc4O)ccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P02 compound treatment 24600.0 -24100.0 -1.39 9760.0 -33500.0 -2.54 -2.7807 -0.9601 1424914 TimTec1_003852 N#CCOc1nc(nc(n1)N2CCCCC2)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P03 compound treatment 33800.0 -14900.0 -0.86 22200.0 -21100.0 -1.6 -1.738 -0.9579 1128232 TimTec1_003853 S=C(NCC1COc2ccccc2O1)NC3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P04 compound treatment 27520.0 -21100.0 -1.22 28400.0 -14900.0 -1.13 -1.6634 -0.9992 3085122 TimTec1_003854 O=C(Nc1nnn[nH]1)C2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P05 compound treatment 21480.0 -27200.0 -1.57 25520.0 -17800.0 -1.35 -2.065 -0.997 3211605 TimTec1_003855 OC1(NC(=C(C#N)C(C1C(=O)c2cccs2)c3ccccc3Cl)SCC=C)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P06 compound treatment 17960.0 -30700.0 -1.78 21480.0 -21800.0 -1.65 -2.4254 -0.9993 1623934 TimTec1_003856 COC(=O)C1=C(C)NC2=C(C1c3cccs3)C(=O)CC(C2)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P07 compound treatment 22600.0 -26100.0 -1.51 29120.0 -14200.0 -1.07 -1.8264 -0.986 1244903 TimTec1_003857 Cc1ccc(cc1)N(CC(=O)c2ccccc2)CC(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P08 compound treatment 33960.0 -14700.0 -0.85 45280.0 1980.0 0.15 -0.4961 -0.5739 3211823 TimTec1_003858 CC/N=C/1\S/C(=C/c2ccc(OCC(=O)O)c(Cl)c2)/C(=O)N1CC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P09 compound treatment 13280.0 -35400.0 -2.05 13000.0 -30300.0 -2.29 -3.071 -0.9984 3085124 TimTec1_003859 O=C(CCn1c(=O)sc2ccccc12)n3c(=O)sc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P10 compound treatment 28400.0 -20300.0 -1.17 30240.0 -13100.0 -0.99 -1.5288 -0.9964 1013674 TimTec1_003860 Clc1ccc(cc1)C(=O)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P11 compound treatment 34440.0 -14200.0 -0.82 30800.0 -12500.0 -0.95 -1.2514 -0.9976 1436854 TimTec1_003861 Cc1oc2CCCCc2c1C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P12 compound treatment 38320.0 -10300.0 -0.6 34200.0 -9100.0 -0.69 -0.9105 -0.9976 3211705 TimTec1_003862 CN(CC(=O)N1CCN(CC1)c2ccccc2)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P13 compound treatment 41560.0 -7090.0 -0.41 32480.0 -10800.0 -0.82 -0.8698 -0.9491 1144432 TimTec1_003863 CSc1ccc(cc1)S(=O)(=O)Nc2c(C)cc(OCC(=O)N3CCOCC3)cc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P14 compound treatment 49240.0 586.0 0.03 42400.0 -901.0 -0.07 -0.0242 -0.3178 3211706 TimTec1_003864 OC(=O)c1ccc2NC(C3C4CCC(C4)C3c2c1)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P15 compound treatment 44440.0 -4210.0 -0.24 38920.0 -4380.0 -0.33 -0.4071 -0.9886 1154434 TimTec1_003865 CN(C)S(=O)(=O)Nc1cccc(N)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P16 compound treatment 41000.0 -7650.0 -0.44 37640.0 -5660.0 -0.43 -0.6166 -0.9999 3211707 TimTec1_003866 COc1ccc(OCCSc2nc3ccccc3o2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P17 compound treatment 35080.0 -13600.0 -0.79 25240.0 -18100.0 -1.37 -1.5228 -0.9655 1371642 TimTec1_003867 CC(Oc1ccccc1Br)C(=O)N2CCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P18 compound treatment 20440.0 -28200.0 -1.63 25360.0 -17900.0 -1.36 -2.1162 -0.9958 3085128 TimTec1_003868 C=CCN(C(=O)C1CCC=CC1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P19 compound treatment 27760.0 -20900.0 -1.21 26960.0 -16300.0 -1.24 -1.7306 -0.9999 1394194 TimTec1_003869 COC(=O)c1c(NC(=O)C2CCCC2)sc3CCCCc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P20 compound treatment 34600.0 -14100.0 -0.81 30360.0 -12900.0 -0.98 -1.2684 -0.9958 3085130 TimTec1_003870 CCC(C)(C)c1ccc(OC2CSC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P21 compound treatment 520.0 -48100.0 -2.79 1120.0 -42200.0 -3.19 -4.2297 -0.9977 3211708 TimTec1_003871 CCc1ccc2OCC(C(F)(F)F)S(=O)(=O)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P22 compound treatment 14880.0 -33800.0 -1.96 19320.0 -24000.0 -1.82 -2.6672 -0.9993 3085131 TimTec1_003872 Oc1ccc(cc1)C(Nc2cccnc2)Sc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P23 mock treatment 44840.0 -3810.0 -0.22 42000.0 -1300.0 -0.1 -0.2259 -0.9337 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2073 P24 mock treatment 45960.0 -2690.0 -0.16 41160.0 -2140.0 -0.16 -0.225 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A01 compound treatment 25560.0 -16900.0 -0.98 45440.0 -1300.0 -0.1 -0.7626 -0.7741 1509421 TimTec1_003873 OC(C1CN2CCC1CC2)(c3cccs3)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A02 compound treatment 27520.0 -15000.0 -0.87 36240.0 -10500.0 -0.79 -1.1747 -0.9991 3085133 TimTec1_003874 Brc1ccc(NCCC(=O)c2ccc3OCOc3c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A03 compound treatment 9320.0 -33200.0 -1.92 22200.0 -24500.0 -1.86 -2.6718 -0.9999 1626877 TimTec1_003875 CCOC(=O)c1cc(sc1NC(=O)CCN2CCN(CC)CC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A04 compound treatment 22280.0 -20200.0 -1.17 22240.0 -24500.0 -1.85 -2.1387 -0.9754 3211709 TimTec1_003876 COC(C(=O)NCc1ccc(Cl)cc1Cl)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A05 compound treatment 24560.0 -17900.0 -1.04 48280.0 1540.0 0.12 -0.6516 -0.6237 3085202 TimTec1_003877 Cc1ccc(Nc2c(O)[nH]c(=O)n2N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A06 compound treatment 34760.0 -7720.0 -0.45 44000.0 -2740.0 -0.21 -0.4628 -0.9389 1917644 TimTec1_003878 CC1=C(C(=O)OCc2ccccc2)C3(O)C(=O)c4ccccc4C3(O)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A07 compound treatment 7600.0 -34900.0 -2.02 8080.0 -38700.0 -2.93 -3.498 -0.9837 3211710 TimTec1_003879 C(N1CCN(CC1)c2ncnc3sc4CCCCCc4c23)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A08 compound treatment 34760.0 -7720.0 -0.45 38880.0 -7860.0 -0.59 -0.7368 -0.9901 1084987 TimTec1_003880 OC(=O)c1ccc2nc(O)c(O)nc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A09 compound treatment 24880.0 -17600.0 -1.02 30560.0 -16200.0 -1.22 -1.5869 -0.9959 3211711 TimTec1_003881 CC(C)c1ccc(NC(=O)NCC2CCCO2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A10 compound treatment 21160.0 -21300.0 -1.24 30840.0 -15900.0 -1.2 -1.7243 -0.9999 1015637 TimTec1_003882 Clc1ccc(cc1)c2cc3ccccc3oc2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A11 compound treatment 14680.0 -27800.0 -1.61 19800.0 -26900.0 -2.04 -2.5807 -0.9932 3211712 TimTec1_003883 Cn1cc(/C(=N\O)/Cc2ccccc2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A12 compound treatment 8320.0 -34200.0 -1.98 16160.0 -30600.0 -2.31 -3.0361 -0.997 3211713 TimTec1_003884 Cc1nn(Cc2cccc(c2)C(=O)Nc3cccc(C)c3C)c(C)c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A13 compound treatment 33640.0 -8840.0 -0.51 46120.0 -619.0 -0.05 -0.3952 -0.7686 1851015 TimTec1_003885 CCc1ccc(OC(=O)COc2ccc(Br)c(C)c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A14 compound treatment 32080.0 -10400.0 -0.6 38080.0 -8660.0 -0.66 -0.8894 -0.9991 3211714 TimTec1_003886 CC1(C)Cc2ccccc2C(=N1)NC(Cc3c[nH]c4ccccc34)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A15 compound treatment 31040.0 -11400.0 -0.66 40040.0 -6700.0 -0.51 -0.8271 -0.9913 1208534 TimTec1_003887 COC(=O)c1ccc(NC(=O)COc2ccc3ccccc3c2Br)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A16 compound treatment 15520.0 -27000.0 -1.56 18840.0 -27900.0 -2.11 -2.5977 -0.989 1464409 TimTec1_003888 COc1ccc(OC)c2c(C)cc(=O)[nH]c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A17 compound treatment 29000.0 -13500.0 -0.78 39400.0 -7340.0 -0.56 -0.9449 -0.9861 1255944 TimTec1_003889 COC(=O)c1ccccc1NC(=O)c2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A18 compound treatment 2880.0 -39600.0 -2.29 3480.0 -43300.0 -3.27 -3.9376 -0.9849 3211715 TimTec1_003890 Cc1nnc(Sc2cc(C)nc3ccccc23)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A19 compound treatment 35800.0 -6680.0 -0.39 45880.0 -859.0 -0.07 -0.3195 -0.8145 3211716 TimTec1_003891 CCOc1ccc(CC(=O)NC2CC(C)(C)N(C)C(C)(C)C2)cc1OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A20 compound treatment 38800.0 -3680.0 -0.21 42120.0 -4620.0 -0.35 -0.3979 -0.9718 225200 TimTec1_003892 Nc1ccn(C2CC(O)C(CO)O2)c(=O)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A21 compound treatment 41240.0 -1240.0 -0.07 42920.0 -3820.0 -0.29 -0.2551 -0.8565 3211717 TimTec1_003893 CC(NC(=O)Cc1c[nH]c2ccccc12)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A22 compound treatment 42840.0 363.0 0.02 56000.0 9260.0 0.7 0.5106 0.728 3085213 TimTec1_003894 Brc1cc(N/C=C\2/C(=O)NC(=S)N(C2=O)c3ccccc3)ccc1N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A23 mock treatment 38840.0 -3640.0 -0.21 48280.0 1540.0 0.12 -0.0665 -0.2762 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 A24 mock treatment 53320.0 10800.0 0.63 55520.0 8780.0 0.66 0.9142 0.9996 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B01 compound treatment 31120.0 -11400.0 -0.66 56600.0 9860.0 0.75 0.0625 0.0628 3211718 TimTec1_003895 OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cc(Br)c(=O)[nH]c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B02 compound treatment 35400.0 -7080.0 -0.41 49640.0 2900.0 0.22 -0.1347 -0.2895 3211719 TimTec1_003896 COC(=O)C1=NNC(C1c2ccccc2)C(=O)OC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B03 compound treatment 30760.0 -11700.0 -0.68 46000.0 -739.0 -0.06 -0.5196 -0.7628 3085215 TimTec1_003897 CN1[C@H](CC(O)c2ccccc2)CCCC1CC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B04 compound treatment 20280.0 -22200.0 -1.29 32800.0 -13900.0 -1.06 -1.6554 -0.9952 3211720 TimTec1_003898 CCOC(=O)CNc1nnc(c2ccccc2)c(c1C#N)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B05 compound treatment 14400.0 -28100.0 -1.63 17560.0 -29200.0 -2.21 -2.712 -0.9887 3085217 TimTec1_003899 COc1c(N)cc(Oc2cccc(c2)C(F)(F)F)c3nc(C)cc(C)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B06 compound treatment 42200.0 -278.0 -0.02 48720.0 1980.0 0.15 0.0947 0.6277 1047737 TimTec1_003900 COC(=O)C1CN(C)CCC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B07 compound treatment 3760.0 -38700.0 -2.24 4440.0 -42300.0 -3.2 -3.8502 -0.9849 3211721 TimTec1_003901 CC(C)(C)c1oc(cc1COCC(F)(F)F)C(=O)Nc2ccc3c(c2)oc4ccccc43 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B08 compound treatment 19040.0 -23400.0 -1.36 31520.0 -15200.0 -1.15 -1.7748 -0.9967 3211722 TimTec1_003902 CC(C)NC(=O)c1ccccc1NC(=O)CN2C(=O)c3cccc4cccc2c34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B09 compound treatment 15040.0 -27400.0 -1.59 19680.0 -27100.0 -2.05 -2.5724 -0.9921 1305957 TimTec1_003903 Clc1cccc(Cl)c1CN(Cc2ccccc2)c3ncnc4[nH]cnc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B10 compound treatment 34320.0 -8160.0 -0.47 45480.0 -1260.0 -0.1 -0.4016 -0.8329 1515666 TimTec1_003904 NNC(=O)C1C2CCCCC12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B11 compound treatment 32840.0 -9640.0 -0.56 47840.0 1100.0 0.08 -0.3359 -0.595 3211723 TimTec1_003905 OC(=O)C(=C1SCCS1)C(=O)/C=C/c2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B12 compound treatment 26680.0 -15800.0 -0.92 38800.0 -7940.0 -0.6 -1.0721 -0.9792 3085287 TimTec1_003906 Cc1ccc(cc1)N2C(=O)C(=CC2(O)c3ccccc3)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B13 compound treatment 25920.0 -16600.0 -0.96 31400.0 -15300.0 -1.16 -1.4993 -0.9955 1580685 TimTec1_003907 CCc1ccccc1NC(=O)C(C(C)C)N2C(=O)c3ccccc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B14 compound treatment 33160.0 -9320.0 -0.54 45120.0 -1620.0 -0.12 -0.4684 -0.8461 3211724 TimTec1_003908 COc1ccccc1N/C(=N\O)/c2nonc2N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B15 compound treatment 37880.0 -4600.0 -0.27 49000.0 2260.0 0.17 -0.0673 -0.2126 3085290 TimTec1_003909 Clc1ccc(cc1)c2ccc(/C=N/C3CCS(=O)(=O)C3)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B16 compound treatment 33280.0 -9200.0 -0.53 45040.0 -1700.0 -0.13 -0.4677 -0.8532 3211725 TimTec1_003910 OC(=O)c1cccc(/N=C/c2ccc(cc2)N3CCOCC3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B17 compound treatment 37240.0 -5240.0 -0.3 46760.0 21.3 0.0 -0.2134 -0.7033 3211726 TimTec1_003911 CCn1c(=O)c(/C=C\2/C(=O)NN=C2c3ccccc3)c(O)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B18 compound treatment 42640.0 163.0 0.01 45640.0 -1100.0 -0.08 -0.0522 -0.6231 3085292 TimTec1_003912 C(=N/c1n[nH]c(\N=C\c2ccccc2)n1)\c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B19 compound treatment 46800.0 4320.0 0.25 43600.0 -3140.0 -0.24 0.0091 0.0263 3211727 TimTec1_003913 FC(F)(F)c1nnc(S)n1/N=C/c2c[nH]c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B20 compound treatment 36480.0 -6000.0 -0.35 45640.0 -1100.0 -0.08 -0.3045 -0.8523 3085294 TimTec1_003914 FC(F)(F)c1ccccc1NC(=O)CSc2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B21 compound treatment 27320.0 -15200.0 -0.88 31600.0 -15100.0 -1.15 -1.4313 -0.9914 1454180 TimTec1_003915 Cc1nn(c(Cl)c1C2N(Cc3ccccc3)CCN2Cc4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B22 compound treatment 36760.0 -5720.0 -0.33 41120.0 -5620.0 -0.43 -0.535 -0.9924 1565629 TimTec1_003916 CCOC(=O)c1c(CN(C)C)n(C)c2cc(Br)c(OC)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B23 mock treatment 39000.0 -3480.0 -0.2 48120.0 1380.0 0.1 -0.0685 -0.3019 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 B24 mock treatment 44880.0 2400.0 0.14 48960.0 2220.0 0.17 0.2173 0.9956 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C01 compound treatment 32160.0 -10300.0 -0.6 42080.0 -4660.0 -0.35 -0.672 -0.9683 1262920 TimTec1_003917 CC(C)NC(=O)c1ccccc1CCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C02 compound treatment 27720.0 -14800.0 -0.86 41080.0 -5660.0 -0.43 -0.9075 -0.9489 3085297 TimTec1_003918 O=C(CCN1CCN(CC1)c2ccccc2)c3ccc4ccccc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C03 compound treatment 52960.0 10500.0 0.61 60760.0 14000.0 1.06 1.1799 0.9649 1344204 TimTec1_003919 COc1ccc(cc1)c2csc(NC(=O)Cc3cccc4ccccc34)c2C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C04 compound treatment 25520.0 -17000.0 -0.98 32360.0 -14400.0 -1.09 -1.4643 -0.9987 3211824 TimTec1_003920 CC(NC(=O)c1ccc(CSc2ccccc2)cc1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C05 compound treatment 25360.0 -17100.0 -0.99 25000.0 -21700.0 -1.65 -1.8648 -0.9706 3085300 TimTec1_003921 NC1=NNC2=C(NNN12)c3ccccc3C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C06 compound treatment 16200.0 -26300.0 -1.52 20640.0 -26100.0 -1.98 -2.4734 -0.9917 1738981 TimTec1_003922 O=c1n(nc(c2ccccc2)c3ccccc13)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C07 compound treatment 16920.0 -25600.0 -1.48 29880.0 -16900.0 -1.28 -1.9494 -0.9973 3085302 TimTec1_003923 COc1cc(/C=C/C)ccc1Oc2nnc(C)c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C08 compound treatment 5360.0 -37100.0 -2.15 14480.0 -32300.0 -2.44 -3.2473 -0.998 1410588 TimTec1_003924 Brc1cccc(NC(=O)c2ccc(OC3CSC3)cc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C09 compound treatment 10040.0 -32400.0 -1.88 15960.0 -30800.0 -2.33 -2.9763 -0.9943 1451839 TimTec1_003925 CC(C)c1ccc(CNC(=O)c2ccc(=O)[nH]c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C10 compound treatment 30600.0 -11900.0 -0.69 36120.0 -10600.0 -0.8 -1.055 -0.997 3211825 TimTec1_003926 COc1ccc(c(OC)c1)c2oc3ccc(OC)cc3c(=O)c2O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C11 compound treatment 34720.0 -7760.0 -0.45 45640.0 -1100.0 -0.08 -0.3766 -0.824 1232921 TimTec1_003927 Cc1ccc(OC(=O)COc2ccc3ccccc3c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C12 compound treatment 18560.0 -23900.0 -1.39 33040.0 -13700.0 -1.04 -1.7131 -0.9898 1881298 TimTec1_003928 CC(C)(C)c1ccccc1NC(=O)c2cccc(Cn3cc(Cl)cn3)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C13 compound treatment 15000.0 -27500.0 -1.59 22160.0 -24600.0 -1.86 -2.4413 -0.997 3085306 TimTec1_003929 CCc1ccc(OC(=O)c2ccc(C)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C14 compound treatment 20640.0 -21800.0 -1.27 33920.0 -12800.0 -0.97 -1.5808 -0.9914 3211826 TimTec1_003930 NS(=O)(=O)c1ccc(Nc2nc(cs2)c3cccs3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C15 compound treatment 34040.0 -8440.0 -0.49 36440.0 -10300.0 -0.78 -0.8969 -0.9747 1544060 TimTec1_003931 Brc1c(OCC(=O)NCCC2=CCCCC2)ccc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C16 compound treatment 27560.0 -14900.0 -0.86 36360.0 -10400.0 -0.79 -1.1667 -0.9989 1058123 TimTec1_003932 COc1ccc(OC)c2c(C)cc(Cl)nc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C17 compound treatment 11600.0 -30900.0 -1.79 22640.0 -24100.0 -1.82 -2.5549 -1.0 1506791 TimTec1_003933 CCC(CC)NC(=O)c1ccc(OC)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C18 compound treatment 41920.0 -558.0 -0.03 52320.0 5580.0 0.42 0.2759 0.6511 1441088 TimTec1_003934 OC(=O)C(NC(=O)CSc1nnnn1c2ccccc2)(c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C19 compound treatment 37120.0 -5360.0 -0.31 47000.0 261.0 0.02 -0.2055 -0.6607 3085378 TimTec1_003935 CN(C)c1nc(N)nc(Cn2ccnc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C20 compound treatment 47080.0 4600.0 0.27 51640.0 4900.0 0.37 0.4509 0.9869 3211827 TimTec1_003936 NNc1ccn(C2OC(CO)C(O)C2O)c(=O)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C21 compound treatment 52040.0 9560.0 0.55 55120.0 8380.0 0.63 0.8404 0.9977 1668209 TimTec1_003937 Nc1nnnn1CC(=O)N(Cc2ccco2)C3(CCCCC3)C(=O)Nc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C22 compound treatment 35360.0 -7120.0 -0.41 30680.0 -16100.0 -1.22 -1.1511 -0.8968 3211828 TimTec1_003938 COCCN1C(=C(C(=O)OC)/C(=C/c2c(Cl)cccc2Cl)/C1=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C23 mock treatment 47800.0 5320.0 0.31 51560.0 4820.0 0.36 0.4761 0.9965 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 C24 mock treatment 51520.0 9040.0 0.52 47240.0 501.0 0.04 0.3973 0.7563 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D01 compound treatment 36200.0 -6280.0 -0.36 49480.0 2740.0 0.21 -0.1105 -0.2638 3085382 TimTec1_003939 CC(=O)OC[C@H]1O[C@H](C[C@@H]1OC(=O)C)n2cc(C)c(=O)[nH]c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D02 compound treatment 25320.0 -17200.0 -0.99 32480.0 -14300.0 -1.08 -1.4661 -0.9992 3211829 TimTec1_003940 Fc1ccc(Nn2c(nc3ccccc3c2=O)c4ccccc4)c(F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D03 compound treatment 19840.0 -22600.0 -1.31 28560.0 -18200.0 -1.38 -1.9004 -0.9997 3085384 TimTec1_003941 CCN(CC)/C=C/C(=O)c1ccccc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D04 compound treatment 34840.0 -7640.0 -0.44 43120.0 -3620.0 -0.27 -0.5066 -0.9734 1632200 TimTec1_003942 CCOC(=O)c1sc(NC(=O)CC)c(C(=O)OCC)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D05 compound treatment 22360.0 -20100.0 -1.17 28240.0 -18500.0 -1.4 -1.8143 -0.9958 3085386 TimTec1_003943 COc1cc2CC3(Cc2cc1OC)N(C)Cc4ccccc43 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D06 compound treatment 37080.0 -5400.0 -0.31 47000.0 261.0 0.02 -0.2071 -0.6611 3211830 TimTec1_003944 CNC(C)[C@@H](O)c1ccc(O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D07 compound treatment 27800.0 -14700.0 -0.85 40120.0 -6620.0 -0.5 -0.9556 -0.9682 1329060 TimTec1_003945 OCC1(CO)COC2(CCCCC2)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D08 compound treatment 22000.0 -20500.0 -1.19 29520.0 -17200.0 -1.3 -1.7605 -0.9989 3211831 TimTec1_003946 CCOC(=O)c1sc(nc1C)n2nc(C)cc2O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D09 compound treatment 19960.0 -22500.0 -1.3 30680.0 -16100.0 -1.22 -1.782 -0.9994 3211832 TimTec1_003947 COc1ccc(cc1)N2CC(=O)N(/N=C/c3ccc(cc3)N(C)C)C2=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D10 compound treatment 31360.0 -11100.0 -0.64 45920.0 -819.0 -0.06 -0.4993 -0.7716 3085389 TimTec1_003948 O=C(CSc1cccc(n1)c2ccccc2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D11 compound treatment 26800.0 -15700.0 -0.91 36000.0 -10700.0 -0.81 -1.2171 -0.9985 3211833 TimTec1_003949 O=C/1Nc2ccccc2\C1=N/N3C(=O)/C(=C/c4ccccc4)/N=C3c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D12 compound treatment 9520.0 -33000.0 -1.91 14880.0 -31900.0 -2.41 -3.0554 -0.9933 1282238 TimTec1_003950 CC(C)NC(=O)COc1ccc(Cl)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D13 compound treatment 6960.0 -35500.0 -2.06 13720.0 -33000.0 -2.5 -3.2224 -0.9953 1920102 TimTec1_003951 FC(F)(F)c1cccc(/N=C/2\C(=O)Nc3ccccc23)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D14 compound treatment 32080.0 -10400.0 -0.6 44000.0 -2740.0 -0.21 -0.5726 -0.8987 3085391 TimTec1_003952 COC1=CC(=O)OC21CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D15 compound treatment 33400.0 -9080.0 -0.53 45080.0 -1660.0 -0.13 -0.4607 -0.852 3085393 TimTec1_003953 CCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)C)C2=O)/c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D16 compound treatment 34000.0 -8480.0 -0.49 39320.0 -7420.0 -0.56 -0.7444 -0.9978 1168752 TimTec1_003954 CCOC(=O)C1=C(C)OC(=C(C(=O)OCC)C21C(=O)Nc3ccccc32)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D17 compound treatment 27040.0 -15400.0 -0.89 30120.0 -16600.0 -1.26 -1.5219 -0.986 1702369 TimTec1_003955 COc1ccc(cc1)c2csc(n2)N3N=C(C)C(C(C(C#N)C(=O)N)c4ccc(Cl)cc4)C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D18 compound treatment 34480.0 -8000.0 -0.46 38320.0 -8420.0 -0.64 -0.7782 -0.9877 3085395 TimTec1_003956 CCOC(=O)c1sc2c(OC)c(Br)ccc2c1NC(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D19 compound treatment 37520.0 -4960.0 -0.29 44520.0 -2220.0 -0.17 -0.3219 -0.9673 3085397 TimTec1_003957 CC1(C)CC(=O)C(=CNc2ncnc3[nH]cnc23)C(=O)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D20 compound treatment 37520.0 -4960.0 -0.29 43280.0 -3460.0 -0.26 -0.3882 -0.9989 1514121 TimTec1_003958 O=C(CCc1ccccc1)Nc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D21 compound treatment 52760.0 10300.0 0.6 44600.0 -2140.0 -0.16 0.3068 0.4969 3211834 TimTec1_003959 OCCNc1ccn(c2nc(sc2c3ccccc3)c4ccccc4)c(=O)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D22 compound treatment 49720.0 7240.0 0.42 47880.0 1140.0 0.09 0.3578 0.8352 1914384 TimTec1_003960 Cc1ccc(CCSCC(=O)O)cn1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D23 mock treatment 35960.0 -6520.0 -0.38 44720.0 -2020.0 -0.15 -0.3751 -0.9207 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 D24 mock treatment 39040.0 -3440.0 -0.2 53320.0 6580.0 0.5 0.2114 0.3941 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E01 compound treatment 26120.0 -16400.0 -0.95 34560.0 -12200.0 -0.92 -1.322 -0.9999 1410817 TimTec1_003961 CCOC(=O)c1c(C)n(Cc2ccccc2)c3ccc(OCC(O)CN4CCCCCC4)cc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E02 compound treatment 26200.0 -16300.0 -0.94 40080.0 -6660.0 -0.5 -1.0233 -0.9569 3085400 TimTec1_003962 CC(C)c1ccc(cc1)C2C(=C(C)Nc3nc4ccccc4n23)C(=O)Nc5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E03 compound treatment 40200.0 -2280.0 -0.13 42840.0 -3900.0 -0.3 -0.302 -0.9341 1389044 TimTec1_003963 Cc1ccc(o1)C(=O)Nc2sc3CCCCc3c2C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E04 compound treatment 46160.0 3680.0 0.21 51960.0 5220.0 0.4 0.4303 0.9581 3084361 TimTec1_003964 Brc1cccc(c1)c2n[nH]c(=S)[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E05 compound treatment 32400.0 -10100.0 -0.58 43520.0 -3220.0 -0.24 -0.5851 -0.9249 3211835 TimTec1_003965 O=C(NCCOc1ccccc1)c2ccc(=O)[nH]c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E06 compound treatment 13160.0 -29300.0 -1.7 18200.0 -28500.0 -2.16 -2.7286 -0.9929 3084365 TimTec1_003966 S=C(NCc1ccccc1)Nc2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E07 compound treatment 21000.0 -21500.0 -1.24 27480.0 -19300.0 -1.46 -1.9107 -0.9969 1680390 TimTec1_003967 CN1CCN(CC1)c2ncnc3sc(C)c(c4ccccc4)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E08 compound treatment 26960.0 -15500.0 -0.9 37240.0 -9500.0 -0.72 -1.1441 -0.9939 1123501 TimTec1_003968 COC(C(=O)NCc1ccc(OC)cc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E09 compound treatment 31800.0 -10700.0 -0.62 41720.0 -5020.0 -0.38 -0.7061 -0.9726 3211836 TimTec1_003969 Clc1ccc(NC(=O)N(Cc2ccccc2)Cc3ccccc3)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E10 compound treatment 23880.0 -18600.0 -1.08 30160.0 -16600.0 -1.25 -1.6493 -0.9971 1804050 TimTec1_003970 CC(SCc1ccccc1)C(=O)Nc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E11 compound treatment 35080.0 -7400.0 -0.43 42920.0 -3820.0 -0.29 -0.5075 -0.9816 1707898 TimTec1_003971 Cc1ccc(o1)C(O)c2nccn2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E12 compound treatment 32440.0 -10000.0 -0.58 45240.0 -1500.0 -0.11 -0.4914 -0.8294 3211977 TimTec1_003972 CCc1c(C)sc(NC(=O)CCCC(=O)O)c1C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E13 compound treatment 27160.0 -15300.0 -0.89 37280.0 -9460.0 -0.72 -1.1338 -0.9943 1707943 TimTec1_003973 CCOc1ccc(NC(=O)CCC(=O)n2nc(cc2c3ccccc3)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E14 compound treatment 27880.0 -14600.0 -0.85 33080.0 -13700.0 -1.03 -1.3291 -0.995 3211915 TimTec1_003974 Cc1ccc(Nc2nc(Nc3ccc(C)cc3)nc(Sc4nnc[nH]4)n2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E15 compound treatment 14920.0 -27600.0 -1.6 20640.0 -26100.0 -1.98 -2.5259 -0.9944 1558319 TimTec1_003975 Brc1c(OCC(=O)NC2CCCCC2)ccc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E16 compound treatment 32680.0 -9800.0 -0.57 40440.0 -6300.0 -0.48 -0.7385 -0.9962 3084371 TimTec1_003976 O=S(=O)(Nc1cccc(c1)C2OCCCO2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E17 compound treatment 17120.0 -25400.0 -1.47 20400.0 -26300.0 -1.99 -2.4486 -0.9887 1490598 TimTec1_003977 Brc1ccccc1NC(=O)c2ccccc2Oc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E18 compound treatment 30240.0 -12200.0 -0.71 36520.0 -10200.0 -0.77 -1.0483 -0.9991 1419531 TimTec1_003978 CC1(C)CC(CCO1)n2c(NCCO)nc3-c4ccccc4CC5(CCCCC5)c3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E19 compound treatment 30400.0 -12100.0 -0.7 41040.0 -5700.0 -0.43 -0.7998 -0.973 3084373 TimTec1_003979 O=C(NC(Cc1ccccc1)C(=O)N2CCCCC2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E20 compound treatment 38800.0 -3680.0 -0.21 52760.0 6020.0 0.46 0.1716 0.3411 3211916 TimTec1_003980 CC1CN(C2CC(O)C(CO)O2)C(=O)NC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E21 compound treatment 43320.0 843.0 0.05 48560.0 1820.0 0.14 0.132 0.9026 1203573 TimTec1_003981 O=C1CC2CS(=O)(=O)CC2N1c3ccc(Oc4ccccc4)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E22 compound treatment 37320.0 -5160.0 -0.3 41080.0 -5660.0 -0.43 -0.5142 -0.9845 3211917 TimTec1_003982 Cc1ccc(cc1)S(=O)(=O)N(CC(=O)NCc2ccncc2)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E23 mock treatment 41600.0 -878.0 -0.05 44760.0 -1980.0 -0.15 -0.1419 -0.8969 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 E24 mock treatment 39480.0 -3000.0 -0.17 49880.0 3140.0 0.24 0.0453 0.154 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F01 compound treatment 37400.0 -5080.0 -0.29 54840.0 8100.0 0.61 0.2256 0.3317 1780915 TimTec1_003983 OCC1OC(Nc2ccc(cc2)C(=O)O)C(O)C1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F02 compound treatment 38000.0 -4480.0 -0.26 39360.0 -7380.0 -0.56 -0.5784 -0.9392 3211918 TimTec1_003984 CN1CCN(CC1)c2nsc(NO)c2Nc3ccc(Br)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F03 compound treatment 15720.0 -26800.0 -1.55 14640.0 -32100.0 -2.43 -2.8143 -0.9764 1313296 TimTec1_003985 Oc1ccccc1C(=O)c2cnn(c2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F04 compound treatment 35160.0 -7320.0 -0.42 45000.0 -1740.0 -0.13 -0.3928 -0.885 3211919 TimTec1_003986 COc1cc(/C=C\2/SC(=S)N(NC(=O)C)C2=O)ccc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F05 compound treatment 520.0 -42000.0 -2.43 600.0 -46100.0 -3.49 -4.1885 -0.9843 3211920 TimTec1_003987 CN(C)c1ccc2N=c3cc(C)c(N)cc3=Sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F06 compound treatment 11600.0 -30900.0 -1.79 18120.0 -28600.0 -2.17 -2.7968 -0.9955 3084378 TimTec1_003988 COc1cc(O)c(C(=O)Cc2ccc(Cl)cc2)c(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F07 compound treatment 26240.0 -16200.0 -0.94 32560.0 -14200.0 -1.07 -1.4241 -0.9978 3211921 TimTec1_003989 CCOC(=O)NC(=S)N1CCN(CC1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F08 compound treatment 16680.0 -25800.0 -1.49 22920.0 -23800.0 -1.8 -2.3318 -0.9957 3084380 TimTec1_003990 Cc1cc(c(C#N)c(SCC(=O)c2ccccc2)n1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F09 compound treatment 31960.0 -10500.0 -0.61 42000.0 -4740.0 -0.36 -0.6845 -0.9681 3211922 TimTec1_003991 Fc1ccc(/C=N/N2C(=O)CN(C2=S)c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F10 compound treatment 36400.0 -6080.0 -0.35 45560.0 -1180.0 -0.09 -0.3121 -0.8591 3084382 TimTec1_003992 Cc1cc(C(=O)Nc2ccccc2)c(o1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F11 compound treatment 23760.0 -18700.0 -1.08 35840.0 -10900.0 -0.82 -1.3502 -0.9909 3084969 TimTec1_003993 CCN(CC)C1=N/C(=C/c2ccccc2)/C(=O)N1c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F12 compound treatment 21880.0 -20600.0 -1.19 29720.0 -17000.0 -1.29 -1.7548 -0.9993 3211923 TimTec1_003994 Brc1ccc(cc1)C(=O)NCCOc2ccccc2Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F13 compound treatment 36440.0 -6040.0 -0.35 46080.0 -659.0 -0.05 -0.2826 -0.7998 3084971 TimTec1_003995 Oc1cc(O)c2sc3nc(cc(c3c2n1)C(F)(F)F)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F14 compound treatment 17640.0 -24800.0 -1.44 24320.0 -22400.0 -1.7 -2.2175 -0.9966 1360453 TimTec1_003996 Cc1ccc(CCC2C3=C(CCCC3=O)OC4=C2C(=O)CCC4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F15 compound treatment 17840.0 -24600.0 -1.43 29200.0 -17500.0 -1.33 -1.9481 -0.9993 3084973 TimTec1_003997 CSc1oc(nc1S(=O)(=O)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F16 compound treatment 34360.0 -8120.0 -0.47 39840.0 -6900.0 -0.52 -0.7018 -0.9986 1588811 TimTec1_003998 CNC(=O)CCC(=O)Nc1cc(Cl)ccc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F17 compound treatment 31200.0 -11300.0 -0.65 42440.0 -4300.0 -0.33 -0.6921 -0.9482 3211924 TimTec1_003999 CCOc1ccc(cc1)C(C)(C)C(=O)NN2C(=O)/C(=C/c3ccccn3)/N=C2c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F18 compound treatment 43800.0 1320.0 0.08 47160.0 421.0 0.03 0.0767 0.9245 3084976 TimTec1_004000 COc1ccc(/C=N/c2nc3ccc(Br)cc3s2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F19 compound treatment 2000.0 -40500.0 -2.35 2600.0 -44100.0 -3.34 -4.0208 -0.985 1627471 TimTec1_004001 O=S(=O)(NCc1ccncc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F20 compound treatment 41400.0 -1080.0 -0.06 51640.0 4900.0 0.37 0.2182 0.58 1030019 TimTec1_004002 CN(C)C(=O)c1ccccc1C(=O)N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F21 compound treatment 38960.0 -3520.0 -0.2 41040.0 -5700.0 -0.43 -0.4491 -0.9414 3084978 TimTec1_004003 N#Cc1nc(oc1NCCCN2CCOCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F22 compound treatment 26760.0 -15700.0 -0.91 29280.0 -17500.0 -1.32 -1.5784 -0.9835 1252023 TimTec1_004004 Cc1cccc(NC(=O)C2C3CCC=CCCC23)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F23 mock treatment 45960.0 3480.0 0.2 55440.0 8700.0 0.66 0.6084 0.8832 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 F24 mock treatment 39600.0 -2880.0 -0.17 48640.0 1900.0 0.14 -0.0161 -0.0732 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G01 compound treatment 22400.0 -20100.0 -1.16 35880.0 -10900.0 -0.82 -1.4037 -0.9855 1401883 TimTec1_004005 Cc1c(C)c2ccccc2n1CC(O)CNCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G02 compound treatment 41800.0 -678.0 -0.04 42680.0 -4060.0 -0.31 -0.245 -0.791 3084981 TimTec1_004006 O=C1OCc2cc(ccc12)n3cnnn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G03 compound treatment 19640.0 -22800.0 -1.32 21040.0 -25700.0 -1.95 -2.3111 -0.9824 3211925 TimTec1_004007 Cc1sc2ncnc(N3CCN(CC3)c4cccc(c4)C(F)(F)F)c2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G04 compound treatment 22960.0 -19500.0 -1.13 27880.0 -18900.0 -1.43 -1.809 -0.9933 1527185 TimTec1_004008 COc1ccccc1c2cc(=O)c3ccccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G05 compound treatment 12240.0 -30200.0 -1.75 16080.0 -30700.0 -2.32 -2.8798 -0.9904 1639456 TimTec1_004009 Oc1ccccc1C(Nc2ccccn2)c3ccc4cccnc4c3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G06 compound treatment 3240.0 -39200.0 -2.27 6560.0 -40200.0 -3.04 -3.758 -0.9897 1650064 TimTec1_004010 Oc1ccccc1C(=O)NCCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G07 compound treatment 22040.0 -20400.0 -1.18 30360.0 -16400.0 -1.24 -1.7139 -0.9997 1085927 TimTec1_004011 CC1CCCCN1C(=O)Nc2cccc(c2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G08 compound treatment 9880.0 -32600.0 -1.89 13640.0 -33100.0 -2.51 -3.107 -0.9903 3085053 TimTec1_004012 O=C(N[C@@H]1C[C@H]2CC[C@@H]1C2)c3ccc(CSc4ccccc4)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G09 compound treatment 12920.0 -29600.0 -1.71 21360.0 -25400.0 -1.92 -2.5693 -0.9984 1516181 TimTec1_004013 C1CN(CC1c2ccccc2)c3nc(cs3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G10 compound treatment 6960.0 -35500.0 -2.06 9960.0 -36800.0 -2.78 -3.4236 -0.9889 3211926 TimTec1_004014 OC(=O)c1ccccc1NC(=O)CCSc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G11 compound treatment 12240.0 -30200.0 -1.75 22440.0 -24300.0 -1.84 -2.5393 -0.9997 1741292 TimTec1_004015 CCCOC(=O)c1ccc(NC(=O)c2ccc(C)c(Br)c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G12 compound treatment 23120.0 -19400.0 -1.12 34160.0 -12600.0 -0.95 -1.4663 -0.9967 3211927 TimTec1_004016 C1CN(CCO1)c2ccc(/N=C/c3ccc(Sc4nc5ccccc5[nH]4)o3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G13 compound treatment 12920.0 -29600.0 -1.71 21440.0 -25300.0 -1.91 -2.565 -0.9984 1267880 TimTec1_004017 COC(=O)c1c(NC(=O)c2ccccc2)sc3CCCc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G14 compound treatment 36200.0 -6280.0 -0.36 42120.0 -4620.0 -0.35 -0.5044 -0.9998 3211928 TimTec1_004018 OC(=O)/C(=C\c1ccco1)/NC(=O)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G15 compound treatment 18000.0 -24500.0 -1.42 21120.0 -25600.0 -1.94 -2.374 -0.9882 1175724 TimTec1_004019 Cc1ccc(NC(=O)c2ccco2)cc1F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G16 compound treatment 25440.0 -17000.0 -0.99 29760.0 -17000.0 -1.29 -1.6068 -0.9915 3211929 TimTec1_004020 Cc1ccc(NCC(=O)SCc2csc(Nc3ccccc3)n2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G17 compound treatment 31000.0 -11500.0 -0.66 28600.0 -18100.0 -1.37 -1.4411 -0.9446 3085059 TimTec1_004021 COc1ccccc1c2nnc(o2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G18 compound treatment 18840.0 -23600.0 -1.37 19960.0 -26800.0 -2.03 -2.4017 -0.9818 3211930 TimTec1_004022 CCOc1ccc(cc1c2nc(=O)c3n(C)nc(c3[nH]2)C(C)(C)C)S(=O)(=O)N4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G19 compound treatment 33080.0 -9400.0 -0.54 44440.0 -2300.0 -0.17 -0.508 -0.8888 3211931 TimTec1_004023 CC(C)CSCC1OC(C(O)C1O)n2cnc3c(N)ncnc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G20 compound treatment 39280.0 -3200.0 -0.19 45280.0 -1460.0 -0.11 -0.2091 -0.9694 907315 TimTec1_004024 CCc1cn(C2CC(O)C(CO)O2)c(=O)[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G21 compound treatment 22400.0 -20100.0 -1.16 28720.0 -18000.0 -1.36 -1.787 -0.9969 1121708 TimTec1_004025 COc1cccc(NC(=O)COc2ccccc2OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G22 compound treatment 35960.0 -6520.0 -0.38 43320.0 -3420.0 -0.26 -0.45 -0.983 1216245 TimTec1_004026 Fc1ccc(cc1)S(=O)(=O)N(CC(=O)NCC2CCCO2)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G23 mock treatment 36880.0 -5600.0 -0.32 48560.0 1820.0 0.14 -0.1318 -0.3741 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 G24 mock treatment 40520.0 -1960.0 -0.11 46760.0 21.3 0.0 -0.0791 -0.697 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H01 compound treatment 44560.0 2080.0 0.12 47400.0 661.0 0.05 0.1207 0.9241 1279518 TimTec1_004027 Nc1cnn(C2OC(COC(=O)c3ccccc3)C(O)C2O)c(=O)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H02 compound treatment 47720.0 5240.0 0.3 55640.0 8900.0 0.67 0.6912 0.9352 3211932 TimTec1_004028 Cc1ccc(C)c(NS(=O)(=O)c2ccc(NC(=N)Nc3nncc(C)n3)cc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H03 compound treatment 35280.0 -7200.0 -0.42 39240.0 -7500.0 -0.57 -0.6962 -0.9885 1187682 TimTec1_004029 COc1ccc(cc1)c2cc(CC(C)C)nc(N)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H04 compound treatment 34720.0 -7760.0 -0.45 42480.0 -4260.0 -0.32 -0.5458 -0.9867 1408114 TimTec1_004030 CCc1ccccc1NC(=O)C(Cc2ccccc2)N3C(=O)c4ccccc4C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H05 compound treatment 20280.0 -22200.0 -1.29 27320.0 -19400.0 -1.47 -1.9488 -0.9978 3211978 TimTec1_004031 CN(C)c1ccc(CCNC(=O)c2ccco2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H06 compound treatment 15560.0 -26900.0 -1.56 22200.0 -24500.0 -1.86 -2.4162 -0.9962 3085065 TimTec1_004032 COc1cccc(c1)c2cc(=O)c3ccc(O)cc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H07 compound treatment 24440.0 -18000.0 -1.05 37480.0 -9260.0 -0.7 -1.2345 -0.9811 3211979 TimTec1_004033 C1CN(CCO1)/C(=N\c2ccccc2)/Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H08 compound treatment 29600.0 -12900.0 -0.75 37760.0 -8980.0 -0.68 -1.0081 -0.9989 3211980 TimTec1_004034 FC(F)(F)c1cc(nc(SCC(=O)c2ccccc2)c1C#N)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H09 compound treatment 33760.0 -8720.0 -0.51 42800.0 -3940.0 -0.3 -0.568 -0.9684 3085068 TimTec1_004035 CC(=O)Nc1ccc(/N=C/c2c[nH]c3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H10 compound treatment 36080.0 -6400.0 -0.37 43280.0 -3460.0 -0.26 -0.4472 -0.9855 3211981 TimTec1_004036 Cc1cc(nc2sc(C(=O)Nc3ccc(cc3)C(=O)N)c(N)c12)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H11 compound treatment 31800.0 -10700.0 -0.62 48080.0 1340.0 0.1 -0.3656 -0.5833 3085069 TimTec1_004037 OCC1OC(Oc2cccc(O)c2CCCc3ccc(O)cc3)C(O)C(O)C1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H12 compound treatment 29040.0 -13400.0 -0.78 39320.0 -7420.0 -0.56 -0.9476 -0.9871 1309367 TimTec1_004038 O=C(N1CCOCC1)c2nc3ccccc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H13 compound treatment 23720.0 -18800.0 -1.09 33240.0 -13500.0 -1.02 -1.491 -0.9995 1455904 TimTec1_004039 CCc1nc2sc(C#N)c(N)c2cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H14 compound treatment 33800.0 -8680.0 -0.5 40360.0 -6380.0 -0.48 -0.6969 -0.9998 1365090 TimTec1_004040 NC(=O)c1ccc(cc1)C(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H15 compound treatment 40120.0 -2360.0 -0.14 53960.0 7220.0 0.55 0.2899 0.5146 1421754 TimTec1_004041 COc1ccc(NCn2c3ccccc3c4ccccc24)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H16 compound treatment 36600.0 -5880.0 -0.34 41920.0 -4820.0 -0.36 -0.4987 -0.9994 1486169 TimTec1_004042 Cc1ccc2N3CCN(C(CCCC(=O)c2c1)C3=O)C(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H17 compound treatment 18080.0 -24400.0 -1.41 16600.0 -30100.0 -2.28 -2.6127 -0.9735 3211982 TimTec1_004043 Cc1ccc(cc1)C2=NNC3(S2)C(=O)Nc4ccccc43 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H18 compound treatment 42480.0 2.5 0.0 42120.0 -4620.0 -0.35 -0.2471 -0.7068 3085139 TimTec1_004044 Cc1ccc2nc(/N=C/c3ccc(Cl)cc3Cl)sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H19 compound treatment 40000.0 -2480.0 -0.14 45840.0 -899.0 -0.07 -0.1496 -0.9418 3211983 TimTec1_004045 CCn1nc(C)c(/N=C/c2ccc(N(C)C)c(Br)c2)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H20 compound treatment 34640.0 -7840.0 -0.45 47160.0 421.0 0.03 -0.2985 -0.6558 1009941 TimTec1_004046 CC(=O)OC(C(=O)c1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H21 compound treatment 47520.0 5040.0 0.29 46320.0 -419.0 -0.03 0.1842 0.6267 1132941 TimTec1_004047 CC1(C)CC(CC(C)(C)N1)N2CCC(O)(C(C2)C(=O)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H22 compound treatment 39440.0 -3040.0 -0.18 45080.0 -1660.0 -0.13 -0.2132 -0.9863 3085143 TimTec1_004048 Cc1cc(=O)[nH]c(SCC(=O)Nc2ccc(Br)cc2)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H23 mock treatment 49760.0 7280.0 0.42 50000.0 3260.0 0.25 0.4729 0.9674 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 H24 mock treatment 33320.0 -9160.0 -0.53 47360.0 621.0 0.05 -0.3419 -0.6419 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I01 compound treatment 44280.0 1800.0 0.1 48040.0 1300.0 0.1 0.1435 0.9996 1679534 TimTec1_004049 COc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)Nc4[nH]c(=O)[nH]c(=O)c24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I02 compound treatment 33400.0 -9080.0 -0.53 42040.0 -4700.0 -0.36 -0.6234 -0.9819 3085145 TimTec1_004050 CN(C)c1nc(N)nc(COc2ccc(C)c(C)c2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I03 compound treatment 37680.0 -4800.0 -0.28 46840.0 101.0 0.01 -0.1911 -0.6873 1257756 TimTec1_004051 O=c1ccc2ccc(Oc3nc(nc4ccccc34)c5cccnc5)cc2o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I04 compound treatment 39400.0 -3080.0 -0.18 46960.0 221.0 0.02 -0.1142 -0.6379 1524978 TimTec1_004052 CCS(=O)(=O)N(CC(=O)N1CCCC1)c2ccc(OC)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I05 compound treatment 6800.0 -35700.0 -2.07 12320.0 -34400.0 -2.61 -3.3039 -0.9934 3211984 TimTec1_004053 FC(F)(F)c1cccc(Nc2ncnc3sc4CCCc4c23)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I06 compound treatment 8560.0 -33900.0 -1.97 10560.0 -36200.0 -2.74 -3.326 -0.9867 1023730 TimTec1_004054 NC(=N)SCc1ccc(Cl)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I07 compound treatment 20480.0 -22000.0 -1.27 30880.0 -15900.0 -1.2 -1.75 -0.9996 3211985 TimTec1_004055 CC1CCCC(C)N1C(=O)Nc2ccc(Cl)c(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I08 compound treatment 21600.0 -20900.0 -1.21 31840.0 -14900.0 -1.13 -1.6528 -0.9994 3085148 TimTec1_004056 CCN(CC)c1ccc(/C=C/C#N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I09 compound treatment 35360.0 -7120.0 -0.41 50400.0 3660.0 0.28 -0.0956 -0.1925 3211986 TimTec1_004057 Cn1c(NC(=O)c2cc(F)c(F)cc2Cl)nc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I10 compound treatment 35800.0 -6680.0 -0.39 40520.0 -6220.0 -0.47 -0.6064 -0.9953 1379820 TimTec1_004058 CCOC(=O)CC(N)c1cccc(O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I11 compound treatment 31520.0 -11000.0 -0.63 40640.0 -6100.0 -0.46 -0.7753 -0.9878 3211987 TimTec1_004059 Cc1ccc(CCC(=O)O)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I12 compound treatment 28760.0 -13700.0 -0.79 38640.0 -8100.0 -0.61 -0.9955 -0.9918 3085152 TimTec1_004060 COc1ccc(/N=C/c2cccn2c3ccc(Br)cc3)cn1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I13 compound treatment 25800.0 -16700.0 -0.97 33240.0 -13500.0 -1.02 -1.4058 -0.9996 3211988 TimTec1_004061 NS(=O)(=O)c1ccc(NC(=O)/C=C/c2ccccc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I14 compound treatment 30640.0 -11800.0 -0.69 37840.0 -8900.0 -0.67 -0.9613 -1.0 1519495 TimTec1_004062 CC1(C)CC(C)(c2ccccc2)c3ccccc3N1C(=O)CSc4nnc[nH]4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I15 compound treatment 34840.0 -7640.0 -0.44 48480.0 1740.0 0.13 -0.2197 -0.4758 1570543 TimTec1_004063 CCOc1ccc(NCC(=O)n2nc(C)cc2C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I16 compound treatment 31920.0 -10600.0 -0.61 42720.0 -4020.0 -0.3 -0.6476 -0.948 3211989 TimTec1_004064 Cc1ccc(SCCNC(=O)c2ccc3ccccc3n2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I17 compound treatment 14080.0 -28400.0 -1.65 15720.0 -31000.0 -2.35 -2.8236 -0.9849 1040036 TimTec1_004065 OCC1OC(C(O)C1O)n2cnc3cncnc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I18 compound treatment 33480.0 -9000.0 -0.52 35880.0 -10900.0 -0.82 -0.9498 -0.9759 3085155 TimTec1_004066 S=C(NCc1ccco1)Nc2ccc3nc(c4ccccn4)c(nc3c2)c5ccccn5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I19 compound treatment 40960.0 -1520.0 -0.09 48120.0 1380.0 0.1 0.0118 0.0861 3211990 TimTec1_004067 OC(Cc1c[nH]c2ccccc12)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I20 compound treatment 39520.0 -2960.0 -0.17 43760.0 -2980.0 -0.23 -0.2806 -0.9908 3551456 TimTec1_004068 CN(C)c1ncnc2n(cnc12)C3OC(CO)C(N)C3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I21 compound treatment 42520.0 42.5 0.0 52920.0 6180.0 0.47 0.3326 0.7108 1678356 TimTec1_004069 COc1ccc(cc1OC)c2n[nH]c(=S)n2c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I22 compound treatment 26800.0 -15700.0 -0.91 34080.0 -12700.0 -0.96 -1.3198 -0.9996 1862685 TimTec1_004070 Fc1cccc(NC(=O)c2cccc(c2)c3cc4ccccc4oc3=O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I23 mock treatment 48280.0 5800.0 0.34 51240.0 4500.0 0.34 0.4786 1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 I24 mock treatment 39440.0 -3040.0 -0.18 47600.0 861.0 0.07 -0.0783 -0.4174 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J01 compound treatment 44880.0 2400.0 0.14 53080.0 6340.0 0.48 0.4378 0.8761 1494538 TimTec1_004071 OC1C(COC(=O)c2ccccc2)OC3C1Oc4nc(=O)ccn34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J02 compound treatment 33800.0 -8680.0 -0.5 42600.0 -4140.0 -0.31 -0.577 -0.9741 3085226 TimTec1_004072 Cc1cc(/C=N/c2ccc(cc2)N3CCOCC3)c(C)n1c4ccc(cc4C)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J03 compound treatment 40360.0 -2120.0 -0.12 49520.0 2780.0 0.21 0.0621 0.2549 3211991 TimTec1_004073 COC(OC)C1(C)NC(=O)c2ccccc2N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J04 compound treatment 14360.0 -28100.0 -1.63 23480.0 -23300.0 -1.76 -2.3968 -0.9992 3211992 TimTec1_004074 CC1=CCC2C(C)(C)[C@@H](O)CCC2(C)C1COc3ccc4ccc(=O)oc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J05 compound treatment 9800.0 -32700.0 -1.89 11920.0 -34800.0 -2.64 -3.2024 -0.9868 3085228 TimTec1_004075 O=C(COc1ccc2ccccc2c1)Nc3ccc(Cc4ccccn4)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J06 compound treatment 30040.0 -12400.0 -0.72 37360.0 -9380.0 -0.71 -1.0115 -1.0 3211993 TimTec1_004076 C[C@H](CSC(=O)C)C(=O)N1CCC[C@H]1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J07 compound treatment 40320.0 -2160.0 -0.13 44600.0 -2140.0 -0.16 -0.2029 -0.9918 3085230 TimTec1_004077 OCC1(CO)COC(=N1)COc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J08 compound treatment 33080.0 -9400.0 -0.54 43400.0 -3340.0 -0.25 -0.5637 -0.9391 3211994 TimTec1_004078 Cc1cc(C)c(C#N)c(SCC(=O)C2CC2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J09 compound treatment 37360.0 -5120.0 -0.3 42040.0 -4700.0 -0.36 -0.4612 -0.9959 1375364 TimTec1_004079 O=C1CC(Nc2ccc(cc2)N3CCOCC3)C(=O)N1c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J10 compound treatment 31680.0 -10800.0 -0.63 38640.0 -8100.0 -0.61 -0.8758 -0.9999 1019637 TimTec1_004080 CN(C)c1nc2cc(Cl)ccc2o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J11 compound treatment 27280.0 -15200.0 -0.88 37040.0 -9700.0 -0.73 -1.1417 -0.9959 3211995 TimTec1_004081 Oc1ccc(cc1)C(=O)NN2C(SCC2=O)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J12 compound treatment 29080.0 -13400.0 -0.78 35280.0 -11500.0 -0.87 -1.1622 -0.9985 3211996 TimTec1_004082 COc1ccc(/C=C/2\C(=O)N(C(c3ccc(F)cc3)S2(=O)=O)c4ccc(Cl)cc4)c(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J13 compound treatment 22040.0 -20400.0 -1.18 29400.0 -17300.0 -1.31 -1.7653 -0.9987 1535419 TimTec1_004083 OC(COc1ccc(cc1)C(=O)c2ccccc2)CN3C(=O)c4ccccc4C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J14 compound treatment 36440.0 -6040.0 -0.35 40440.0 -6300.0 -0.48 -0.5845 -0.9884 1646040 TimTec1_004084 CCOC(=O)C1=C(C)NC(=O)NC1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J15 compound treatment 39920.0 -2560.0 -0.15 39600.0 -7140.0 -0.54 -0.4869 -0.8689 1413879 TimTec1_004085 Ic1ccc2nc(c3ccccc3)n(NC(=S)NCC=C)c(=O)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J16 compound treatment 40120.0 -2360.0 -0.14 46600.0 -139.0 -0.01 -0.104 -0.7592 1498022 TimTec1_004086 O=C1C2C(C(C=CC2c3ccccc3)c4ccccc4)C(=O)N1Cc5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J17 compound treatment 28760.0 -13700.0 -0.79 39640.0 -7100.0 -0.54 -0.9419 -0.9818 1546528 TimTec1_004087 CCC(=O)N(C(=O)CC)c1cc2oc3ccccc3c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J18 compound treatment 42560.0 82.5 0.0 49320.0 2580.0 0.2 0.1415 0.7242 3211997 TimTec1_004088 COc1ccc(/C=N/c2nc3c(ccc4ccccc34)s2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J19 compound treatment 47080.0 4600.0 0.27 45240.0 -1500.0 -0.11 0.1083 0.3738 3085236 TimTec1_004089 OCc1coc(O)c(CN2CCCCC2)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J20 compound treatment 43240.0 763.0 0.04 48520.0 1780.0 0.13 0.1266 0.8921 1049537 TimTec1_004090 OCCNC(=O)c1ccc(cc1)C(=O)NCCO 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J21 compound treatment 41760.0 -718.0 -0.04 40080.0 -6660.0 -0.5 -0.3858 -0.7628 3085238 TimTec1_004091 O=c1[nH]cnc2ccc(NC(=S)NC3CC3)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J22 compound treatment 24440.0 -18000.0 -1.05 24160.0 -22600.0 -1.71 -1.9475 -0.9721 1129244 TimTec1_004092 Brc1ccc2[nH]c3C(CCCc3c2c1)NCc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J23 mock treatment 38800.0 -3680.0 -0.21 44720.0 -2020.0 -0.15 -0.2587 -0.9867 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 J24 mock treatment 40960.0 -1520.0 -0.09 45760.0 -979.0 -0.07 -0.1146 -0.9964 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K01 compound treatment 22120.0 -20400.0 -1.18 33200.0 -13500.0 -1.02 -1.5587 -0.9975 3085240 TimTec1_004093 Cc1ccc(Cl)c(c1)C(=O)NC2=CC(=O)CC(C)(C)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K02 compound treatment 34200.0 -8280.0 -0.48 36400.0 -10300.0 -0.78 -0.8925 -0.9724 3212056 TimTec1_004094 COC(OC)C1Nc2ccccc2C(=O)N1c3cccc(c3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K03 compound treatment 29560.0 -12900.0 -0.75 44520.0 -2220.0 -0.17 -0.648 -0.8448 1870332 TimTec1_004095 COc1ccc(cc1)c2cc(c3ccccc3O)n(n2)C4C(=O)Nc5ccc(Br)cc45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K04 compound treatment 8960.0 -33500.0 -1.94 14000.0 -32700.0 -2.48 -3.1255 -0.9927 3085242 TimTec1_004096 CC(C)(C)NC(=S)NCc1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K05 compound treatment 8680.0 -33800.0 -1.96 10840.0 -35900.0 -2.72 -3.3061 -0.9871 1547474 TimTec1_004097 CN1CCN(CC1)C(c2ccncc2)c3ccc4cccnc4c3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K06 compound treatment 14560.0 -27900.0 -1.62 18240.0 -28500.0 -2.16 -2.6691 -0.9899 1031437 TimTec1_004098 COc1cc(CC=C)ccc1OCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K07 compound treatment 30360.0 -12100.0 -0.7 37560.0 -9180.0 -0.69 -0.9877 -1.0 3212057 TimTec1_004099 FC(F)(F)c1cccc(NC(=O)N2CCN(Cc3ccccc3)CC2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K08 compound treatment 19000.0 -23500.0 -1.36 24120.0 -22600.0 -1.71 -2.1725 -0.9935 3085313 TimTec1_004100 O=C1CC(N(N=C1C#N)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K09 compound treatment 28840.0 -13600.0 -0.79 33520.0 -13200.0 -1.0 -1.2662 -0.9932 1194194 TimTec1_004101 O=C(CCC(=O)Nc1cccc2ccccc12)Nc3cccc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K10 compound treatment 28440.0 -14000.0 -0.81 28080.0 -18700.0 -1.41 -1.5738 -0.9656 3085314 TimTec1_004102 O[C@H]1CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]2C1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K11 compound treatment 18800.0 -23700.0 -1.37 23360.0 -23400.0 -1.77 -2.2213 -0.9921 3212058 TimTec1_004103 Cc1ccc2nc(sc2c1)c3ccc(NC(=O)[C@@H]4CCCC[C@@H]4C(=O)O)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K12 compound treatment 22280.0 -20200.0 -1.17 31640.0 -15100.0 -1.14 -1.6356 -0.9999 3212059 TimTec1_004104 Cc1cccc(OCCNC(=O)c2cccnc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K13 compound treatment 16520.0 -26000.0 -1.5 23440.0 -23300.0 -1.76 -2.3105 -0.9969 1300948 TimTec1_004105 COC(=O)c1c(NC(=O)C)sc2CCCc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K14 compound treatment 32960.0 -9520.0 -0.55 32440.0 -14300.0 -1.08 -1.1552 -0.951 3085318 TimTec1_004106 CCN(CC)C(=O)c1nn(C)c(=O)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K15 compound treatment 16560.0 -25900.0 -1.5 17240.0 -29500.0 -2.23 -2.6407 -0.9814 1423050 TimTec1_004107 CS(=O)(=O)N(Cc1ccccc1)c2ccccc2C(=O)Nc3cccc(Br)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K16 compound treatment 36760.0 -5720.0 -0.33 35720.0 -11000.0 -0.83 -0.824 -0.9182 3212060 TimTec1_004108 OCCCc1nnc(SC(=O)O)n1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K17 compound treatment 36640.0 -5840.0 -0.34 40400.0 -6340.0 -0.48 -0.5784 -0.9853 3085320 TimTec1_004109 Cc1cc(C)n(n1)C(=O)CSc2ccc(cc2)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K18 compound treatment 40040.0 -2440.0 -0.14 44560.0 -2180.0 -0.16 -0.2165 -0.997 3212061 TimTec1_004110 Fc1ccc(cc1)S(=O)(=O)Nc2nonc2NS(=O)(=O)c3ccc(F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K19 compound treatment 14920.0 -27600.0 -1.6 26240.0 -20500.0 -1.55 -2.2262 -0.9999 3085322 TimTec1_004111 CC1(C)[C@H]2CCC1(CS(=O)(=O)N(C3CCCCC3)C4CCCCC4)C(O)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K20 compound treatment 14800.0 -27700.0 -1.6 21520.0 -25200.0 -1.91 -2.4837 -0.9962 3212062 TimTec1_004112 COC(=O)C/1=C(C)NC(=O)\C1=C/c2ccc(cc2)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K21 compound treatment 19120.0 -23400.0 -1.35 20720.0 -26000.0 -1.97 -2.3495 -0.9832 1494618 TimTec1_004113 COc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)Nc4ccc(C)cc4C)sc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K22 compound treatment 40560.0 -1920.0 -0.11 32280.0 -14500.0 -1.09 -0.8524 -0.7749 1021964 TimTec1_004114 NCCc1ccc(cc1)S(=O)(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K23 mock treatment 40040.0 -2440.0 -0.14 40840.0 -5900.0 -0.45 -0.4156 -0.8874 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 K24 mock treatment 33600.0 -8880.0 -0.51 36960.0 -9780.0 -0.74 -0.8871 -0.9842 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L01 compound treatment 28000.0 -14500.0 -0.84 33200.0 -13500.0 -1.02 -1.3178 -0.9951 1265817 TimTec1_004115 Cc1ccc(NC2OC(CO)C(O)C2O)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L02 compound treatment 36960.0 -5520.0 -0.32 39720.0 -7020.0 -0.53 -0.6017 -0.9704 3212063 TimTec1_004116 O=C(CSc1nnc(c2ccccc2)n1CCN3CCOCC3)NC4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L03 compound treatment 36320.0 -6160.0 -0.36 41760.0 -4980.0 -0.38 -0.5187 -0.9996 3085326 TimTec1_004117 Cc1cc(C(=O)O)c(CSCc2cc(oc2C)C(=O)O)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L04 compound treatment 26760.0 -15700.0 -0.91 35000.0 -11700.0 -0.89 -1.2722 -0.9999 1576521 TimTec1_004118 COc1ccc(CN(CCCN)CCC2(CC(C)N(C)CC2C)c3ccccc3)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L05 compound treatment 20880.0 -21600.0 -1.25 24600.0 -22100.0 -1.68 -2.0698 -0.9896 3212064 TimTec1_004119 CCCc1cc2OCOc2cc1NC(=O)C(C)(C)C(=O)Nc3cc4OCOc4cc3CCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L06 compound treatment 13560.0 -28900.0 -1.68 16680.0 -30100.0 -2.28 -2.7936 -0.9887 3085328 TimTec1_004120 Oc1cccc(c1)c2cc(=O)c3cc(O)ccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L07 compound treatment 38560.0 -3920.0 -0.23 39240.0 -7500.0 -0.57 -0.5619 -0.9191 3085330 TimTec1_004121 Nc1cccc(c1)C2OCCCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L08 compound treatment 33600.0 -8880.0 -0.51 34800.0 -11900.0 -0.9 -1.0027 -0.9643 3212065 TimTec1_004122 Cc1cc(=O)[nH]c(SCC(=O)C2(CC3CC4CC(C3)C2)C4)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L09 compound treatment 37800.0 -4680.0 -0.27 40880.0 -5860.0 -0.44 -0.5052 -0.9721 1408553 TimTec1_004123 CC(C)NC(=O)C(Cc1ccccc1)N2C(=O)c3ccccc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L10 compound treatment 24120.0 -18400.0 -1.06 29600.0 -17100.0 -1.3 -1.6694 -0.9951 3085403 TimTec1_004124 Cc1cc2COC(=O)c2c(Sc3ccccc3)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L11 compound treatment 19560.0 -22900.0 -1.33 19680.0 -27100.0 -2.05 -2.3872 -0.978 3212066 TimTec1_004125 O=C/1OC(=N\C1=C/2\OC(=O)c3ccccc23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L12 compound treatment 8120.0 -34400.0 -1.99 14000.0 -32700.0 -2.48 -3.1599 -0.9941 1563075 TimTec1_004126 O=C1CCCC2=C1C(Nc3ccc4ccccc4c23)c5cccnc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L13 compound treatment 6520.0 -36000.0 -2.08 9960.0 -36800.0 -2.78 -3.4417 -0.9898 3085407 TimTec1_004127 Fc1ccc(C/N=C\c2cc3ccccc3nc2Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L14 compound treatment 28760.0 -13700.0 -0.79 29560.0 -17200.0 -1.3 -1.4815 -0.9721 1705522 TimTec1_004128 Oc1ccc(cc1CN2CCN(CCC#N)CC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L15 compound treatment 34800.0 -7680.0 -0.44 33800.0 -12900.0 -0.98 -1.0071 -0.9362 3085409 TimTec1_004129 COc1cc(ccc1O)c2nc(S)nc(N)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L16 compound treatment 42960.0 483.0 0.03 39760.0 -6980.0 -0.53 -0.3538 -0.6688 1136694 TimTec1_004130 Cc1cccc(NC(=O)CNC(=O)OCc2ccccc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L17 compound treatment 42600.0 123.0 0.01 51360.0 4620.0 0.35 0.2524 0.7213 1605978 TimTec1_004131 Cn1c(=O)c(c2cc(c3ccccc3C(=O)NN)n(n2)c4ccccc4)c(O)c5ccccc15 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L18 compound treatment 37000.0 -5480.0 -0.32 38840.0 -7900.0 -0.6 -0.6472 -0.9561 3085412 TimTec1_004132 CCOc1ccc(cc1)[C@H]2[C@@H]3CN(Cc4ccccc4)CC=C3C(=C(N)C2(C#N)C#N)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L19 compound treatment 36920.0 -5560.0 -0.32 44840.0 -1900.0 -0.14 -0.3293 -0.9339 3212067 TimTec1_004133 C(NC1=NC=N2CCn3cnc1c23)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L20 compound treatment 46960.0 4480.0 0.26 53400.0 6660.0 0.5 0.5402 0.9524 1912645 TimTec1_004134 CC(=O)n1nc(C)cc1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L21 compound treatment 43680.0 1200.0 0.07 45840.0 -899.0 -0.07 0.0012 0.0119 3085414 TimTec1_004135 Sc1nnc(COc2ccccc2Cl)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L22 compound treatment 33760.0 -8720.0 -0.51 42360.0 -4380.0 -0.33 -0.5915 -0.9791 1409212 TimTec1_004136 COc1ccccc1CNC(=O)COc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L23 mock treatment 44320.0 1840.0 0.11 47000.0 261.0 0.02 0.0895 0.8241 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 L24 mock treatment 41720.0 -758.0 -0.04 42120.0 -4620.0 -0.35 -0.2782 -0.7897 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M01 compound treatment 33360.0 -9120.0 -0.53 36400.0 -10300.0 -0.78 -0.9269 -0.9817 1608236 TimTec1_004137 CC(C)c1ccc(cc1)c2csc3ncn(N)c(=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M02 compound treatment 5000.0 -37500.0 -2.17 6080.0 -40700.0 -3.08 -3.7116 -0.9854 3212068 TimTec1_004138 Cn1c(=O)n(C)c2cc(CN3C(=O)c4ccccc4C3=O)ccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M03 compound treatment 23200.0 -19300.0 -1.12 28880.0 -17900.0 -1.35 -1.7456 -0.9955 1233601 TimTec1_004139 Cc1nn(c2CC(CC(=O)c12)c3ccco3)c4ccccn4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M04 compound treatment 8000.0 -34500.0 -2.0 12280.0 -34500.0 -2.61 -3.2568 -0.9913 1300398 TimTec1_004140 O=C(NC1CC1)c2ccc(CN(c3ccccc3)S(=O)(=O)c4ccccc4)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M05 compound treatment 4240.0 -38200.0 -2.22 1640.0 -45100.0 -3.41 -3.9804 -0.9781 1190193 TimTec1_004141 Cc1[nH]c2ccccc2c1C(N3CCN(CC3)c4ccccc4)c5cccs5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M06 compound treatment 35440.0 -7040.0 -0.41 43640.0 -3100.0 -0.23 -0.4542 -0.9655 1227000 TimTec1_004142 NNc1ccc2[nH]c(=O)[nH]c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M07 compound treatment 33040.0 -9440.0 -0.55 36280.0 -10500.0 -0.79 -0.9464 -0.9837 1560140 TimTec1_004143 Fc1ccc(Cn2cnc3ccccc3c2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M08 compound treatment 40680.0 -1800.0 -0.1 42560.0 -4180.0 -0.32 -0.2973 -0.8928 3212133 TimTec1_004144 CC(=O)O[C@@]1(CCC2C3CCC4=CC(=O)CC[C@]4(C)C3[C@@H](O)C[C@@]21C)C(=O)CO 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M09 compound treatment 15240.0 -27200.0 -1.58 20640.0 -26100.0 -1.98 -2.5128 -0.9938 3085420 TimTec1_004145 Brc1ccc(o1)C(=O)Nc2ccc(C#N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M10 compound treatment 1240.0 -41200.0 -2.39 1080.0 -45700.0 -3.46 -4.1333 -0.9837 3212134 TimTec1_004146 CCC1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]4NCCc5cc(OC)c(OC)cc45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M11 compound treatment 30680.0 -11800.0 -0.68 34240.0 -12500.0 -0.95 -1.1523 -0.9873 3085422 TimTec1_004147 C[C@@H]1CC2(CCCN2Cc3ccccc3)C[C@H]1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M12 compound treatment 38480.0 -4000.0 -0.23 38360.0 -8380.0 -0.63 -0.6122 -0.9068 3085423 TimTec1_004148 O=C(NCCN1CCN=C1c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M13 compound treatment 29680.0 -12800.0 -0.74 30640.0 -16100.0 -1.22 -1.386 -0.9716 1325497 TimTec1_004149 CCC(=O)Nc1ccccc1C(=O)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M14 compound treatment 21000.0 -21500.0 -1.24 23000.0 -23700.0 -1.8 -2.1505 -0.9839 3085425 TimTec1_004150 O=c1cc(CSc2nc3ccccc3s2)c4ccccc4[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M15 compound treatment 39200.0 -3280.0 -0.19 38600.0 -8140.0 -0.62 -0.5699 -0.884 1732529 TimTec1_004151 CC(C)NS(=O)(=O)c1ccc(NC(=O)C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M16 compound treatment 15480.0 -27000.0 -1.56 15440.0 -31300.0 -2.37 -2.7813 -0.9797 1321742 TimTec1_004152 CC(C)(C)NC(=O)CSc1nc2ccccc2n1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M17 compound treatment 8160.0 -34300.0 -1.99 10600.0 -36100.0 -2.74 -3.3402 -0.9877 3212135 TimTec1_004153 O=S(=O)(NCCCn1ccnc1)c2ccc3ccccc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M18 compound treatment 32160.0 -10300.0 -0.6 25000.0 -21700.0 -1.65 -1.5862 -0.906 3084387 TimTec1_004154 Cc1ccc(cc1S(=O)(=O)NC(C)(C)CO)c2nnc(N3CCOCC3)c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M19 compound treatment 41120.0 -1360.0 -0.08 38440.0 -8300.0 -0.63 -0.4998 -0.7895 1026799 TimTec1_004155 OC(=O)c1ccc(Br)c(c1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M20 compound treatment 49920.0 7440.0 0.43 46760.0 21.3 0.0 0.306 0.7097 3212136 TimTec1_004156 OC(=O)c1ccc(cc1)N2N=C(/C(=C/c3ccc(o3)c4ccc5C(=O)NC(=O)c5c4)/C2=O)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M21 compound treatment 29640.0 -12800.0 -0.74 30920.0 -15800.0 -1.2 -1.3726 -0.9738 3084389 TimTec1_004157 COc1ccc(cc1)C2CC(=O)Nc3cc4OCOc4cc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M22 compound treatment 47280.0 4800.0 0.28 45240.0 -1500.0 -0.11 0.1165 0.3878 3069528 TimTec1_004158 C/C=C\1/C[C@@H](C)[C@](O)(CO)C(=O)OCC2=CCN3CC[C@@H](OC1=O)[C@H]32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M23 mock treatment 38760.0 -3720.0 -0.22 44120.0 -2620.0 -0.2 -0.2925 -0.9991 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 M24 mock treatment 42400.0 -77.5 0.0 47160.0 421.0 0.03 0.0194 0.6016 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N01 compound treatment 40840.0 -1640.0 -0.09 48560.0 1820.0 0.14 0.0304 0.1816 3212137 TimTec1_004159 OCC1OC(CC1O)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N02 compound treatment 320.0 -42200.0 -2.44 360.0 -46400.0 -3.51 -4.2095 -0.9843 3212138 TimTec1_004160 CC/1=NNC(=O)\C1=C/c2cn(nc2c3ccc(F)cc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N03 compound treatment 38800.0 -3680.0 -0.21 40080.0 -6660.0 -0.5 -0.5071 -0.9266 3084392 TimTec1_004161 Cn1cnnc1c2ccc(N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N04 compound treatment 6880.0 -35600.0 -2.06 8520.0 -38200.0 -2.89 -3.504 -0.9862 3084393 TimTec1_004162 CN(Cc1ccccc1)C(=O)Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N05 compound treatment 29800.0 -12700.0 -0.73 31440.0 -15300.0 -1.16 -1.3382 -0.9759 3212139 TimTec1_004163 Cc1nc2ccc(NC(=O)C(C)(C)C(=O)Nc3ccc4nc(C)c(C)nc4c3)cc2nc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N06 compound treatment 30640.0 -11800.0 -0.69 32720.0 -14000.0 -1.06 -1.2353 -0.9777 3084395 TimTec1_004164 Cc1ccccc1OCc2nnc(S)n2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N07 compound treatment 17600.0 -24900.0 -1.44 19880.0 -26900.0 -2.03 -2.4568 -0.9858 3212140 TimTec1_004165 O=C(/C=C/c1cccs1)C(=C2SCCCCS2)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N08 compound treatment 38440.0 -4040.0 -0.23 37000.0 -9740.0 -0.74 -0.6867 -0.8879 1485279 TimTec1_004166 CCOC(=O)C1=C(C)NC2(O)CC1C3COC2O3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N09 compound treatment 27680.0 -14800.0 -0.86 37200.0 -9540.0 -0.72 -1.1168 -0.9964 1264107 TimTec1_004167 Cc1ccc(cc1)C2Nc3ccc4ccccc4c3C5=C2C(=O)CC(C)(C)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N10 compound treatment 22200.0 -20300.0 -1.17 23200.0 -23500.0 -1.78 -2.0906 -0.9796 1616817 TimTec1_004168 CCc1nc(SCC(=O)C(C)(C)C)c(C#N)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N11 compound treatment 22600.0 -19900.0 -1.15 25880.0 -20900.0 -1.58 -1.9308 -0.988 1253074 TimTec1_004169 O=C(NC(=S)NCc1ccco1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N12 compound treatment 17800.0 -24700.0 -1.43 21800.0 -24900.0 -1.89 -2.3458 -0.9906 3084399 TimTec1_004170 Cc1[nH]c2ccccc2c1/C=N/c3c(nc4ccccn34)c5ccco5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N13 compound treatment 39640.0 -2840.0 -0.16 39960.0 -6780.0 -0.51 -0.4791 -0.8891 1017704 TimTec1_004171 Nc1ncnc2[nH]c(nc12)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N14 compound treatment 22280.0 -20200.0 -1.17 26640.0 -20100.0 -1.52 -1.9032 -0.9916 3212141 TimTec1_004172 CCOC(=O)c1sc(SC#N)c(c1N)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N15 compound treatment 42360.0 -118.0 -0.01 41480.0 -5260.0 -0.4 -0.2863 -0.7191 1004708 TimTec1_004173 COc1ccccc1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N16 compound treatment 36800.0 -5680.0 -0.33 42280.0 -4460.0 -0.34 -0.4712 -0.9999 1222145 TimTec1_004174 CC(C)N1CC(COc2ccccc2)OC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N17 compound treatment 33080.0 -9400.0 -0.54 34240.0 -12500.0 -0.95 -1.054 -0.9656 3084402 TimTec1_004175 Cc1cc(N)n(n1)c2ncnc3sc4CCCCc4c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N18 compound treatment 38560.0 -3920.0 -0.23 41800.0 -4940.0 -0.37 -0.4248 -0.9714 1166305 TimTec1_004176 Cc1ccc(cc1S)S(=O)(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N19 compound treatment 10360.0 -32100.0 -1.86 14040.0 -32700.0 -2.48 -3.066 -0.9901 3212142 TimTec1_004177 Cc1nc2ccccc2nc1N/C(=N/C(=O)c3ccccc3)/N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N20 compound treatment 42880.0 403.0 0.02 40600.0 -6140.0 -0.46 -0.3121 -0.6708 1378550 TimTec1_004178 O=C1CCC(=O)N1CNc2ccc(cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N21 compound treatment 29760.0 -12700.0 -0.74 29720.0 -17000.0 -1.29 -1.4319 -0.9649 3212143 TimTec1_004179 Cc1nc2ccc(NC(=O)N3CC4(C)CC3CC(C)(C)C4)cc2nc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N22 compound treatment 45000.0 2520.0 0.15 41160.0 -5580.0 -0.42 -0.1953 -0.437 1205779 TimTec1_004180 NC(=O)c1cc2ccccc2oc1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N23 mock treatment 37480.0 -5000.0 -0.29 43680.0 -3060.0 -0.23 -0.3685 -0.9939 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 N24 mock treatment 38280.0 -4200.0 -0.24 43720.0 -3020.0 -0.23 -0.3335 -0.9995 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O01 compound treatment 4560.0 -37900.0 -2.2 7240.0 -39500.0 -2.99 -3.6675 -0.9885 1144219 TimTec1_004181 Cc1sc2ncnc(N3CCN(Cc4ccccc4)CC3)c2c1c5ccc(F)cc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O02 compound treatment 49520.0 7040.0 0.41 46080.0 -659.0 -0.05 0.2533 0.6161 3084915 TimTec1_004182 COc1ccc(cc1OC)c2nnc(SC)n2CC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O03 compound treatment 48400.0 5920.0 0.34 48840.0 2100.0 0.16 0.3551 0.9389 1582942 TimTec1_004183 CC1=CCC(C(C1)c2ccc(Br)cc2)(C(=O)O)C(=O)NCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O04 compound treatment 22000.0 -20500.0 -1.19 29640.0 -17100.0 -1.29 -1.7541 -0.9991 1277662 TimTec1_004184 COc1ccc(cc1)C(=O)NC2CCCCC2NC(=O)c3ccc(OC)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O05 compound treatment 14200.0 -28300.0 -1.64 11640.0 -35100.0 -2.66 -3.0371 -0.973 1305407 TimTec1_004185 Fc1ccc(cc1)c2csc3ncnc(Oc4ccc5ccc(=O)oc5c4)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O06 compound treatment 17560.0 -24900.0 -1.44 39560.0 -7180.0 -0.54 -1.4051 -0.9109 3212144 TimTec1_004186 OC(=O)c1cc(ccc1Cl)N2N=C(/C(=C/c3ccc(o3)c4ccccc4)/C2=O)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O07 compound treatment 4960.0 -37500.0 -2.17 6080.0 -40700.0 -3.08 -3.7132 -0.9855 3084918 TimTec1_004187 COC(=O)c1nn(c(Br)c1C(=O)OC)c2ccc(Br)cc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O08 compound treatment 5720.0 -36800.0 -2.13 6120.0 -40600.0 -3.07 -3.68 -0.9839 3084920 TimTec1_004188 COc1cc(Br)c(CN(CCc2ccc(O)cc2)C(=O)C(F)(F)F)cc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O09 compound treatment 34160.0 -8320.0 -0.48 36280.0 -10500.0 -0.79 -0.9005 -0.9717 1388832 TimTec1_004189 Clc1ccccc1C(=O)NC2CCCCC2NC(=O)c3ccccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O10 compound treatment 21600.0 -20900.0 -1.21 24000.0 -22700.0 -1.72 -2.0724 -0.9851 1535096 TimTec1_004190 CC(C)c1ccc(cc1)C2C(=C(N)Oc3c2n(C(=O)C)c4ccccc34)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O11 compound treatment 18680.0 -23800.0 -1.38 25000.0 -21700.0 -1.65 -2.1385 -0.9961 1851014 TimTec1_004191 COc1ccc2c(Cl)c(sc2c1)C(=O)Oc3ccccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O12 compound treatment 1040.0 -41400.0 -2.4 920.0 -45800.0 -3.47 -4.15 -0.9839 1407017 TimTec1_004192 CCN(CC)c1ccc2c(c1)oc(=O)c3c(Cl)cc(=O)oc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O13 compound treatment 47920.0 5440.0 0.32 45000.0 -1740.0 -0.13 0.1299 0.3802 1440352 TimTec1_004193 OC(=O)c1ccccc1C(=O)N2CCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O14 compound treatment 37200.0 -5280.0 -0.31 44760.0 -1980.0 -0.15 -0.3221 -0.9461 3084985 TimTec1_004194 COC(=O)Nc1ncc(CN2CCC(C)CC2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O15 compound treatment 44280.0 1800.0 0.1 50520.0 3780.0 0.29 0.2762 0.9066 1441746 TimTec1_004195 O=C(Cc1ccccc1)NN(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O16 compound treatment 28040.0 -14400.0 -0.84 31040.0 -15700.0 -1.19 -1.4317 -0.9852 1247973 TimTec1_004196 CC1CCCCN1C(=O)c2ccccc2NS(=O)(=O)c3ccc4ccccc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O17 compound treatment 47920.0 5440.0 0.32 47920.0 1180.0 0.09 0.2862 0.8732 3084989 TimTec1_004197 CCOCC(O)CSc1nc(C)cc(C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O18 compound treatment 53920.0 11400.0 0.66 46360.0 -379.0 -0.03 0.4485 0.6759 1089162 TimTec1_004198 OCC1OC(C(O)C1O)n2ccc(NC(=O)c3ccccc3)nc2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O19 compound treatment 51160.0 8680.0 0.5 52480.0 5740.0 0.43 0.663 0.9973 3084991 TimTec1_004199 CC1(C)[C@H]2CCC1(CS(=O)(=O)N)C(=O)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O20 compound treatment 45480.0 3000.0 0.17 48120.0 1380.0 0.1 0.1969 0.9703 3212307 TimTec1_004200 OC(=O)c1cc(cc(c1)c2ccc(/C=N\c3ccc4[nH]c(=O)[nH]c4c3)o2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O21 compound treatment 50880.0 8400.0 0.49 45800.0 -939.0 -0.07 0.294 0.5976 3084993 TimTec1_004201 Clc1ccc(cc1)C2NC(=O)NC(=C2)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O22 compound treatment 38520.0 -3960.0 -0.23 28720.0 -18000.0 -1.36 -1.1266 -0.8145 1067834 TimTec1_004202 NCCC(c1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O23 mock treatment 56520.0 14000.0 0.81 44600.0 -2140.0 -0.16 0.4608 0.5555 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 O24 mock treatment 52040.0 9560.0 0.55 39200.0 -7540.0 -0.57 -0.0117 -0.0148 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P01 compound treatment 38760.0 -3720.0 -0.22 50760.0 4020.0 0.3 0.0629 0.1688 3212216 TimTec1_004203 CC(C)(C)C1(O)CC2OC(=O)CC23C(=O)OC4OC(=O)C(O)C413 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P02 compound treatment 46880.0 4400.0 0.26 51640.0 4900.0 0.37 0.4427 0.9833 1735319 TimTec1_004204 CCOC(=O)c1nn(c2ccc(Cl)cc2)c(=N)c3c(N)c(C#N)c(N)nc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P03 compound treatment 25320.0 -17200.0 -0.99 34040.0 -12700.0 -0.96 -1.3826 -0.9999 3212217 TimTec1_004205 COc1cc2C[C@@H]3N(C)CCc4c(N)c(OC)c(OC)c(-c2cc1OC)c34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P04 compound treatment 4320.0 -38200.0 -2.21 13880.0 -32900.0 -2.49 -3.322 -0.9983 3084996 TimTec1_004206 Oc1ccc2cc(c3cccc(Br)c3)c(=O)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P05 compound treatment 18320.0 -24200.0 -1.4 34520.0 -12200.0 -0.92 -1.6437 -0.9798 3212218 TimTec1_004207 Cc1ccc(cc1Cl)C(=O)NC2CS(=O)(=O)CC2NC(=O)c3ccc(C)c(Cl)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P06 compound treatment 34360.0 -8120.0 -0.47 44560.0 -2180.0 -0.16 -0.4492 -0.9013 1055533 TimTec1_004208 NC(=O)c1c(F)c(F)c(N)c(F)c1F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P07 compound treatment 35160.0 -7320.0 -0.42 47680.0 941.0 0.07 -0.2494 -0.5801 3212219 TimTec1_004209 OC1=CC(O)(N(/N=C/2\C(=O)Nc3ccc(Br)cc23)C1=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P08 compound treatment 17720.0 -24800.0 -1.43 34040.0 -12700.0 -0.96 -1.694 -0.981 3084999 TimTec1_004210 CC/C(=N/O)/C(=O)c1ccc(Br)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P09 compound treatment 25240.0 -17200.0 -1.0 34120.0 -12600.0 -0.96 -1.3816 -0.9998 1118292 TimTec1_004211 COc1ccc(NC(=O)CC(=O)c2ccccc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P10 compound treatment 20280.0 -22200.0 -1.29 30520.0 -16200.0 -1.23 -1.7775 -0.9997 3212220 TimTec1_004212 CC1(C)N2CN(CCCCN3CN4N(C3)C4(C)C)CN21 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P11 compound treatment 21960.0 -20500.0 -1.19 40480.0 -6260.0 -0.47 -1.1756 -0.9186 3085001 TimTec1_004213 FC(F)(F)c1ccccc1NCn2nnc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P12 compound treatment 27320.0 -15200.0 -0.88 42040.0 -4700.0 -0.36 -0.8725 -0.9208 1471541 TimTec1_004214 OC(=O)CCNc1ccc(Br)cc1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P13 compound treatment 31320.0 -11200.0 -0.65 44040.0 -2700.0 -0.2 -0.6015 -0.8873 3212221 TimTec1_004215 CCOC(=O)c1[nH]c(=O)[nH]c1CC2C(=O)CC(C)(C)CC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P14 compound treatment 33720.0 -8760.0 -0.51 46000.0 -739.0 -0.06 -0.3983 -0.7803 1913403 TimTec1_004216 CN(C)c1nc(OC(C(F)(F)F)C(F)(F)F)nc(n1)N(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P15 compound treatment 33800.0 -8680.0 -0.5 45200.0 -1540.0 -0.12 -0.4379 -0.8485 1008937 TimTec1_004217 C(COc1ccccc1)Oc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P16 compound treatment 32480.0 -10000.0 -0.58 42600.0 -4140.0 -0.31 -0.6311 -0.9584 1247888 TimTec1_004218 O=C(CSc1ccccn1)NCC(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P17 compound treatment 8080.0 -34400.0 -1.99 22840.0 -23900.0 -1.81 -2.6884 -0.9988 1266971 TimTec1_004219 C(Sc1nc2ccccc2o1)c3cccc(Oc4ccccc4)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P18 compound treatment 27560.0 -14900.0 -0.86 35120.0 -11600.0 -0.88 -1.233 -1.0 3212222 TimTec1_004220 Cc1nnc(SCc2ccc(F)cc2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P19 compound treatment 30800.0 -11700.0 -0.68 42040.0 -4700.0 -0.36 -0.7299 -0.9549 1377201 TimTec1_004221 O=C1N(CCNS(=O)(=O)c2ccc3oc4ccccc4c3c2)Cc5ccccc15 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P20 compound treatment 46760.0 4280.0 0.25 48400.0 1660.0 0.13 0.2644 0.9504 1474244 TimTec1_004222 CC1(C)Cc2c(CO1)c(nc3sc(cc23)C(=O)O)N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P21 compound treatment 31160.0 -11300.0 -0.66 36480.0 -10300.0 -0.78 -1.0127 -0.9965 3212223 TimTec1_004223 COc1cccc2C(CC(=O)c3ccc(O)cc3)C4=C(CC(C)(C)CC4=O)Oc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P22 compound treatment 49040.0 6560.0 0.38 49160.0 2420.0 0.18 0.3984 0.944 3085007 TimTec1_004224 CC(=CCS(=O)(=O)c1ccccc1)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P23 mock treatment 43840.0 1360.0 0.08 44600.0 -2140.0 -0.16 -0.0587 -0.3257 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2074 P24 mock treatment 45320.0 2840.0 0.16 43200.0 -3540.0 -0.27 -0.073 -0.232 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A01 compound treatment 55440.0 3550.0 0.21 43760.0 440.0 0.03 0.1689 0.8111 3085008 TimTec1_004225 CC(=C)CS(=O)(=O)c1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A02 compound treatment 50000.0 -1890.0 -0.11 47320.0 4000.0 0.3 0.1366 0.4241 1397478 TimTec1_004226 COc1ccc(NC(=O)C2C(=C2c3ccccc3)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A03 compound treatment 7160.0 -44700.0 -2.59 8360.0 -35000.0 -2.65 -3.7038 -0.9999 1295145 TimTec1_004227 CCOC(=O)C1(C(CC(=O)CC1c2ccccc2)c3ccccc3)C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A04 compound treatment 44200.0 -7690.0 -0.45 30360.0 -13000.0 -0.98 -1.0088 -0.9363 1717498 TimTec1_004228 CC(C)(C)C(=O)NCCc1c[nH]c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A05 compound treatment 2200.0 -49700.0 -2.88 2800.0 -40500.0 -3.07 -4.2046 -0.9995 3212224 TimTec1_004229 CC(C)(COC(=O)c1ccccc1)NC2=NS(=O)(=O)c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A06 compound treatment 48560.0 -3330.0 -0.19 43280.0 -40.0 0.0 -0.1387 -0.7181 1324852 TimTec1_004230 CC1CC(O)(Cc2ccc(C)cc2)C(C)CN1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A07 compound treatment 51480.0 -413.0 -0.02 38760.0 -4560.0 -0.35 -0.261 -0.7543 1528736 TimTec1_004231 COc1cccc(CC(C)C(=O)N)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A08 compound treatment 34280.0 -17600.0 -1.02 35560.0 -7760.0 -0.59 -1.1369 -0.9656 3212225 TimTec1_004232 COc1c(ccc2ccccc12)C(=O)NCCOc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A09 compound treatment 53560.0 1670.0 0.1 43360.0 40.0 0.0 0.0705 0.7289 3212226 TimTec1_004233 CC(=O)OCC(=O)[C@@]1(O)CCC2C3CCC4CC(=O)CCC4(C)C3CCC21C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A10 compound treatment 39960.0 -11900.0 -0.69 40320.0 -3000.0 -0.23 -0.6494 -0.8925 1391256 TimTec1_004234 O=C(COc1cccc(OCC(=O)Nc2ccccn2)c1)Nc3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A11 compound treatment 53600.0 1710.0 0.1 40080.0 -3240.0 -0.25 -0.1035 -0.3912 3085079 TimTec1_004235 CN(CP(=O)(O)CN1CCCC1=O)C(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A12 compound treatment 47680.0 -4210.0 -0.24 43120.0 -200.0 -0.02 -0.1833 -0.7495 1155490 TimTec1_004236 OC(=O)CN(CC(=O)O)c1ccc(Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A13 compound treatment 50440.0 -1450.0 -0.08 38960.0 -4360.0 -0.33 -0.2929 -0.8599 3085081 TimTec1_004237 O/N=C/C(=O)Nc1ccccc1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A14 compound treatment 13520.0 -38400.0 -2.22 11280.0 -32000.0 -2.43 -3.287 -0.9991 1152383 TimTec1_004238 COc1ccc(NC(=O)C2C3C2C4CCC3C4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A15 compound treatment 39640.0 -12300.0 -0.71 34480.0 -8840.0 -0.67 -0.9751 -0.9996 1199333 TimTec1_004239 O=C(NCc1ccccc1)C2CC2(c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A16 compound treatment 14520.0 -37400.0 -2.17 7600.0 -35700.0 -2.7 -3.443 -0.9939 3212227 TimTec1_004240 Cc1ccc(cc1)C(=O)CC(C(C#N)C#N)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A17 compound treatment 48360.0 -3530.0 -0.2 38160.0 -5160.0 -0.39 -0.4209 -0.9545 3085083 TimTec1_004241 O=c1[nH][nH]c(=O)c2c(/N=C/c3cccc4ccccc34)cccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A18 compound treatment 18320.0 -33600.0 -1.95 14880.0 -28400.0 -2.15 -2.8976 -0.9987 3212228 TimTec1_004242 COc1ccc(OC)c(NC(=O)C2C3CC/C=C/CC\C=C/CCC23)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A19 compound treatment 20960.0 -30900.0 -1.79 13640.0 -29700.0 -2.25 -2.8558 -0.9937 3085086 TimTec1_004243 Brc1ccccc1NC(=O)CSc2nc3ccccc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A20 compound treatment 27240.0 -24700.0 -1.43 21400.0 -21900.0 -1.66 -2.1832 -0.9972 3212229 TimTec1_004244 COc1ccc(cc1)N2C(=O)C(=CC2(OC)c3ccccc3)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A21 compound treatment 23080.0 -28800.0 -1.67 14480.0 -28800.0 -2.18 -2.724 -0.9912 3085088 TimTec1_004245 CN(C)/N=C/c1ccc(OC(=O)c2ccc(Br)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A22 compound treatment 17680.0 -34200.0 -1.98 21600.0 -21700.0 -1.64 -2.5642 -0.9957 3212230 TimTec1_004246 O=C(CSc1ccccn1)N2CCCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A23 mock treatment 59960.0 8070.0 0.47 48960.0 5640.0 0.43 0.6324 0.999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 A24 mock treatment 64800.0 12900.0 0.75 57560.0 14200.0 1.08 1.291 0.984 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B01 compound treatment 52800.0 908.0 0.05 38400.0 -4920.0 -0.37 -0.2262 -0.6013 1674437 TimTec1_004247 CCN1N=C(C)C=C(C)n2c1nc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B02 compound treatment 32160.0 -19700.0 -1.14 33320.0 -10000.0 -0.76 -1.3436 -0.98 1696382 TimTec1_004248 Cc1ccc(NC(=O)C2C3CCCCC=CC23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B03 compound treatment 52480.0 588.0 0.03 43120.0 -200.0 -0.02 0.0134 0.3587 3212231 TimTec1_004249 CCC1SC(=NC1=O)Nc2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B04 compound treatment 57200.0 5310.0 0.31 36640.0 -6680.0 -0.51 -0.1401 -0.2367 1427335 TimTec1_004250 C=CCN(CC=C)S(=O)(=O)c1ncn[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B05 compound treatment 13320.0 -38600.0 -2.23 12520.0 -30800.0 -2.33 -3.2288 -0.9998 3085092 TimTec1_004251 Nc1cc(ccc1OCc2ccccc2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B06 compound treatment 22360.0 -29500.0 -1.71 14360.0 -29000.0 -2.19 -2.7599 -0.9925 3212232 TimTec1_004252 CN(C)c1c(C(=C(C#N)C#N)C#N)c2ccccc2n1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B07 compound treatment 47240.0 -4650.0 -0.27 40760.0 -2560.0 -0.19 -0.3276 -0.9869 3085094 TimTec1_004253 OC(=O)c1ccc(CSc2ccccn2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B08 compound treatment 45240.0 -6650.0 -0.39 36800.0 -6520.0 -0.49 -0.6215 -0.9925 1347619 TimTec1_004254 CCC1NC(=S)NC(=C1C(=O)c2ccccc2)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B09 compound treatment 47720.0 -4170.0 -0.24 40880.0 -2440.0 -0.18 -0.3015 -0.9912 3085159 TimTec1_004255 CCOc1ccc(cc1NC(=O)C)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B10 compound treatment 54280.0 2390.0 0.14 44440.0 1120.0 0.08 0.1578 0.9724 1518737 TimTec1_004256 CCC(=O)N1N=C2CC(C)(C)OCC2C1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B11 compound treatment 51280.0 -613.0 -0.04 41920.0 -1400.0 -0.11 -0.1 -0.895 1335526 TimTec1_004257 CCOC(=O)c1nnn(c1CN2CCSCC2)c3nonc3N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B12 compound treatment 20680.0 -31200.0 -1.81 16960.0 -26400.0 -2.0 -2.6896 -0.9988 1291333 TimTec1_004258 CC1(C)NN(C(=S)N1)c2nc3ccccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B13 compound treatment 55240.0 3350.0 0.19 47880.0 4560.0 0.35 0.3812 0.9628 1385793 TimTec1_004259 Cc1nn(c(O)c1C2CC(=O)N(C2=O)c3ccccc3)c4cccc(Cl)c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B14 compound treatment 43000.0 -8890.0 -0.52 37080.0 -6240.0 -0.47 -0.6983 -0.9991 1213104 TimTec1_004260 CC(CC(=O)C1C(C)C=CCC1(C)C)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B15 compound treatment 54960.0 3070.0 0.18 42720.0 -600.0 -0.05 0.0936 0.51 3212233 TimTec1_004261 CN/C(=N\C)/SC1CC(=O)N(C1=O)c2ccccc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B16 compound treatment 27640.0 -24300.0 -1.41 17120.0 -26200.0 -1.98 -2.3959 -0.9858 1345990 TimTec1_004262 CCC(=O)Nc1ccccc1C(=O)OCC(=O)Nc2nc3ccc(cc3s2)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B17 compound treatment 55280.0 3390.0 0.2 40880.0 -2440.0 -0.18 0.0082 0.0304 1326177 TimTec1_004263 COc1cccc2c(CCN)c[nH]c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B18 compound treatment 1240.0 -50700.0 -2.93 1120.0 -42200.0 -3.19 -4.3339 -0.9991 3085165 TimTec1_004264 CCC1=C(C)/C(=C\c2[nH]c(C)c(CC)c2C)/N=C1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B19 compound treatment 48960.0 -2930.0 -0.17 37760.0 -5560.0 -0.42 -0.4177 -0.9204 3212234 TimTec1_004265 CCOc1cc(/C=C/2\OC(=O)c3c2cc(C)[nH]c3=S)ccc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B20 compound treatment 49680.0 -2210.0 -0.13 35080.0 -8240.0 -0.62 -0.5317 -0.835 1379087 TimTec1_004266 Cc1ccc(OCc2nn(CN3CCC4(CC3)OCCO4)c(=S)n2C)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B21 compound treatment 65640.0 13700.0 0.8 44200.0 880.0 0.07 0.6103 0.7636 1413553 TimTec1_004267 CCC(Sc1nnc(C)c(=O)[nH]1)C(=O)Nc2ccccc2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B22 compound treatment 55760.0 3870.0 0.22 46400.0 3080.0 0.23 0.3233 0.9998 3212308 TimTec1_004268 COc1ccc(Br)cc1S(=O)(=O)NCCCN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B23 mock treatment 54360.0 2470.0 0.14 47720.0 4400.0 0.33 0.3366 0.9287 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 B24 mock treatment 56240.0 4350.0 0.25 48640.0 5320.0 0.4 0.4629 0.9745 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C01 compound treatment 57360.0 5470.0 0.32 45000.0 1680.0 0.13 0.3139 0.9196 1539639 TimTec1_004269 COc1ccc(cc1)C(N)CC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C02 compound treatment 11560.0 -40300.0 -2.34 8040.0 -35300.0 -2.67 -3.5407 -0.9978 1192605 TimTec1_004270 O=C(NCCc1ccccc1)c2ccc(o2)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C03 compound treatment 48160.0 -3730.0 -0.22 39560.0 -3760.0 -0.28 -0.3542 -0.9908 3085169 TimTec1_004271 NC/1=C(C#N)C(=N)S\C1=C\c2ccc(Cl)c(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C04 compound treatment 11080.0 -40800.0 -2.36 7400.0 -35900.0 -2.72 -3.5946 -0.9976 3212309 TimTec1_004272 CCCCC(CC)CNC1=NS(=O)(=O)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C05 compound treatment 57560.0 5670.0 0.33 40800.0 -2520.0 -0.19 0.0973 0.2562 1436367 TimTec1_004273 CSc1nc2nc(N)nc(N)c2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C06 compound treatment 32840.0 -19100.0 -1.1 24520.0 -18800.0 -1.42 -1.7868 -0.9921 3212310 TimTec1_004274 COc1ccc(Cc2nnc(S)s2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C07 compound treatment 43920.0 -7970.0 -0.46 37480.0 -5840.0 -0.44 -0.6392 -0.9998 3085173 TimTec1_004275 OC(=O)CSC1=CC(=O)N(C1=O)c2cccc(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C08 compound treatment 47480.0 -4410.0 -0.26 39360.0 -3960.0 -0.3 -0.3927 -0.9969 1438726 TimTec1_004276 Cc1ccnc(c1)N2C(=O)OC(C)(C)C2(C)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C09 compound treatment 50280.0 -1610.0 -0.09 39360.0 -3960.0 -0.3 -0.278 -0.8855 1517107 TimTec1_004277 CC(=O)N1CCN2C(=O)C1CCCC(=O)c3cc(ccc23)C4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C10 compound treatment 42480.0 -9410.0 -0.55 36440.0 -6880.0 -0.52 -0.7539 -0.9997 1430711 TimTec1_004278 COC(=O)c1cccc(NC(=O)COC(=O)c2cc3ccccc3o2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C11 compound treatment 51320.0 -573.0 -0.03 41480.0 -1840.0 -0.14 -0.1219 -0.8517 1141099 TimTec1_004279 OC(=O)CCS(=O)(=O)c1ccc2ccccc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C12 compound treatment 56040.0 4150.0 0.24 45000.0 1680.0 0.13 0.2598 0.9557 3085175 TimTec1_004280 Cc1cccc(c1)n2nn[nH]c2=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C13 compound treatment 25160.0 -26700.0 -1.55 18440.0 -24900.0 -1.88 -2.4269 -0.9953 3212311 TimTec1_004281 Brc1ccc(/C=C/2\C(=O)NN(C2=O)c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C14 compound treatment 55360.0 3470.0 0.2 41800.0 -1520.0 -0.12 0.0607 0.2622 1600116 TimTec1_004282 NS(=O)(=O)c1ncn(Cc2ccccc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C15 compound treatment 9960.0 -41900.0 -2.43 8720.0 -34600.0 -2.62 -3.5698 -0.9993 1916017 TimTec1_004283 Nc1ccc(cc1)c2cnc(nc2)c3ccc(N)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C16 compound treatment 48400.0 -3490.0 -0.2 36360.0 -6960.0 -0.53 -0.5156 -0.9136 1129774 TimTec1_004284 CCOC(=O)c1oc2ccccc2c1NC(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C17 compound treatment 29760.0 -22100.0 -1.28 25080.0 -18200.0 -1.38 -1.883 -0.9993 1248984 TimTec1_004285 COc1ccc(NC(=O)c2ccc3ccccc3c2OC)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C18 compound treatment 10360.0 -41500.0 -2.41 8200.0 -35100.0 -2.66 -3.5813 -0.9988 3085247 TimTec1_004286 CC(NC(=O)Nc1ccccc1Br)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C19 compound treatment 50840.0 -1050.0 -0.06 43200.0 -120.0 -0.01 -0.0495 -0.8036 1510374 TimTec1_004287 COc1ccc(NC(=O)C2CCC(=O)N2C(=O)OCc3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C20 compound treatment 58000.0 6110.0 0.35 42600.0 -720.0 -0.05 0.2117 0.5912 3085249 TimTec1_004288 CC1(C)Cc2ccccc2C(=N1)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C21 compound treatment 55240.0 3350.0 0.19 38320.0 -5000.0 -0.38 -0.1305 -0.3068 1404871 TimTec1_004289 O=C(N1CCSC1c2ccccc2)c3cc4ccccc4oc3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C22 compound treatment 60800.0 8910.0 0.52 42920.0 -400.0 -0.03 0.3435 0.6645 1143185 TimTec1_004290 CC(C)(C)C(=O)N1CCCC1C(=O)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C23 mock treatment 53800.0 1910.0 0.11 45000.0 1680.0 0.13 0.1681 0.9976 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 C24 mock treatment 61440.0 9550.0 0.55 47720.0 4400.0 0.33 0.6266 0.9705 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D01 compound treatment 53480.0 1590.0 0.09 40240.0 -3080.0 -0.23 -0.0998 -0.3983 3212312 TimTec1_004291 CCC(SC1=NC(=O)C(C(=O)N1)c2ccccc2)C(=O)Nc3sc4CCCCc4c3C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D02 compound treatment 2240.0 -49700.0 -2.88 1800.0 -41500.0 -3.14 -4.2565 -0.999 1681507 TimTec1_004292 S=C(SCc1ccc(CSC(=S)N2CCOCC2)cc1)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D03 compound treatment 50000.0 -1890.0 -0.11 43280.0 -40.0 0.0 -0.0797 -0.7264 1369855 TimTec1_004293 CCC(=O)N1CCC(CC1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D04 compound treatment 12760.0 -39100.0 -2.27 8920.0 -34400.0 -2.6 -3.4444 -0.9976 1327254 TimTec1_004294 O=C1C(C(=O)c2ccccc12)C3=Nc4ccccc4NC(C3)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D05 compound treatment 45360.0 -6530.0 -0.38 34360.0 -8960.0 -0.68 -0.7472 -0.962 1670837 TimTec1_004295 OC(C#CCN1CCCC1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D06 compound treatment 36120.0 -15800.0 -0.91 23640.0 -19700.0 -1.49 -1.6995 -0.9725 3085254 TimTec1_004296 Nc1ccc2nc(SCC(=O)c3ccc(F)cc3)sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D07 compound treatment 29480.0 -22400.0 -1.3 24120.0 -19200.0 -1.45 -1.9459 -0.9984 1149209 TimTec1_004297 Cn1ccnc1SCC(=O)Nc2ccccc2Oc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D08 compound treatment 37720.0 -14200.0 -0.82 27720.0 -15600.0 -1.18 -1.4156 -0.9842 1583796 TimTec1_004298 OC(=O)c1ccc(cc1)c2cnc3ccccc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D09 compound treatment 48280.0 -3610.0 -0.21 40920.0 -2400.0 -0.18 -0.2765 -0.9975 1479857 TimTec1_004299 Nc1ccc(OCC(=O)N2CCOCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D10 compound treatment 13560.0 -38300.0 -2.22 15600.0 -27700.0 -2.1 -3.0541 -0.9996 1457410 TimTec1_004300 C(Nc1ccc2oc(nc2c1)c3ccccc3)c4cccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D11 compound treatment 11880.0 -40000.0 -2.32 17240.0 -26100.0 -1.97 -3.0351 -0.9968 3085258 TimTec1_004301 CC(=O)OC1(CN2CCC1CC2)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D12 compound treatment 46880.0 -5010.0 -0.29 40000.0 -3320.0 -0.25 -0.3831 -0.9974 1325596 TimTec1_004302 CC(=O)N1C(O)C(O)N(C(=O)C)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D13 compound treatment 46840.0 -5050.0 -0.29 34640.0 -8680.0 -0.66 -0.6716 -0.9337 3085259 TimTec1_004303 CNC(=N)NC(=O)Nc1c(C)cccc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D14 compound treatment 45760.0 -6130.0 -0.36 33720.0 -9600.0 -0.73 -0.7651 -0.9458 1635468 TimTec1_004304 COc1ccc2n(c(C)c(C(=O)N3CCN(C)CC3)c2c1)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D15 compound treatment 49920.0 -1970.0 -0.11 33800.0 -9520.0 -0.72 -0.5904 -0.8091 1665310 TimTec1_004305 CC1(C)CC(=O)CC(=C1)NCC2CCCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D16 compound treatment 28240.0 -23700.0 -1.37 25040.0 -18300.0 -1.38 -1.9474 -1.0 1262068 TimTec1_004306 Cc1cc(=O)oc2c3c(OC(=O)c4ccccc4)coc3c(NC(=O)c5ccccc5)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D17 compound treatment 52680.0 788.0 0.05 41400.0 -1920.0 -0.15 -0.0705 -0.4628 1639736 TimTec1_004307 CC(C)OC(=O)C1C(C2CC1C=C2)C(=O)NCC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D18 compound treatment 55240.0 3350.0 0.19 39840.0 -3480.0 -0.26 -0.0491 -0.1502 3212313 TimTec1_004308 O=C(CSc1nnc[nH]1)C2CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D19 compound treatment 51760.0 -133.0 -0.01 37840.0 -5480.0 -0.41 -0.2987 -0.7201 1018938 TimTec1_004309 O=C(N1CCN(CC1)C(=O)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D20 compound treatment 59480.0 7590.0 0.44 43240.0 -80.0 -0.01 0.3066 0.6973 1028190 TimTec1_004310 COc1ccc(CC(O)CN2CCOCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D21 compound treatment 57640.0 5750.0 0.33 42720.0 -600.0 -0.05 0.2033 0.6051 1610412 TimTec1_004311 CC(C)(C)OC(=O)N1CC(O)CC1C(=O)N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D22 compound treatment 16280.0 -35600.0 -2.06 11800.0 -31500.0 -2.39 -3.1461 -0.9974 1636298 TimTec1_004312 Cn1ccnc1SCC(=O)N2c3ccccc3CCc4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D23 mock treatment 53120.0 1230.0 0.07 44440.0 1120.0 0.08 0.1102 0.9962 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 D24 mock treatment 57480.0 5590.0 0.32 46000.0 2680.0 0.2 0.3724 0.9747 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E01 compound treatment 42440.0 -9450.0 -0.55 33720.0 -9600.0 -0.73 -0.9011 -0.9903 3212314 TimTec1_004313 CC(=O)NCC(c1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E02 compound treatment 53280.0 1390.0 0.08 43240.0 -80.0 -0.01 0.0526 0.652 1202468 TimTec1_004314 O=C(NCN1CCN(Cc2ccccc2)CC1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E03 compound treatment 41680.0 -10200.0 -0.59 29040.0 -14300.0 -1.08 -1.1827 -0.9598 3085337 TimTec1_004315 COc1ccc(/N=C/c2ccc(Sc3ccccn3)o2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E04 compound treatment 39200.0 -12700.0 -0.74 23640.0 -19700.0 -1.49 -1.5733 -0.9471 1420647 TimTec1_004316 O=C(COC(=O)c1ccco1)N2c3ccccc3Sc4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E05 compound treatment 33640.0 -18300.0 -1.06 25520.0 -17800.0 -1.35 -1.7005 -0.9928 1547103 TimTec1_004317 CC(N1C(=O)CCC1=O)C(=O)Oc2ccc3c(C)cc(=O)oc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E06 compound treatment 42200.0 -9690.0 -0.56 34360.0 -8960.0 -0.68 -0.8767 -0.9956 1714581 TimTec1_004318 Cc1ccc(CCP(=O)(O)CN2CCCCC2)cn1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E07 compound treatment 14800.0 -37100.0 -2.15 8320.0 -35000.0 -2.65 -3.393 -0.9946 3085340 TimTec1_004319 Cc1ccc(NC(=O)CC2CCC2)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E08 compound treatment 46360.0 -5530.0 -0.32 34760.0 -8560.0 -0.65 -0.6848 -0.9473 3212315 TimTec1_004320 Cc1cc(C)nc(n1)N2C(=C)C(C)(C)OC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E09 compound treatment 48800.0 -3090.0 -0.18 36320.0 -7000.0 -0.53 -0.5014 -0.8964 3085343 TimTec1_004321 Cc1sc(/N=C/c2ccc(Cl)c(Cl)c2)c(C#N)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E10 compound treatment 2320.0 -49600.0 -2.87 2040.0 -41300.0 -3.12 -4.2404 -0.9991 1671390 TimTec1_004322 Ic1ccc(Nc2nc3nonc3n4nnnc24)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E11 compound treatment 49520.0 -2370.0 -0.14 34800.0 -8520.0 -0.64 -0.5532 -0.839 1687107 TimTec1_004323 CN1CCC(O)(CC1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E12 compound treatment 55000.0 3110.0 0.18 36760.0 -6560.0 -0.5 -0.2238 -0.4237 1215551 TimTec1_004324 COC(=O)C1=C(N)N(C2=C(C1c3ccc(OC)cc3)C(=O)CCC2)c4ccc(cc4)S(=O)(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E13 compound treatment 46520.0 -5370.0 -0.31 32520.0 -10800.0 -0.82 -0.7982 -0.9124 1516816 TimTec1_004325 Clc1cccc(OCCN2CCN(CC2)c3ccccc3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E14 compound treatment 43000.0 -8890.0 -0.52 31760.0 -11600.0 -0.88 -0.983 -0.9681 3212316 TimTec1_004326 O=C(CCCc1ccccc1)NC2CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E15 compound treatment 49960.0 -1930.0 -0.11 35000.0 -8320.0 -0.63 -0.5245 -0.82 1919871 TimTec1_004327 CCS(=O)(=O)C(=C1Nc2ccccc2N1)S(=O)(=O)CC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E16 compound treatment 45040.0 -6850.0 -0.4 33920.0 -9400.0 -0.71 -0.7839 -0.962 1212477 TimTec1_004328 CCOC(=O)C1=C(C)OC(=C(C#N)C21C(=O)Nc3ccc(C)cc32)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E17 compound treatment 41920.0 -9970.0 -0.58 30320.0 -13000.0 -0.98 -1.1044 -0.9678 3212317 TimTec1_004329 Nc1ccnc(c1C(=O)c2ccccc2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E18 compound treatment 28280.0 -23600.0 -1.37 22600.0 -20700.0 -1.57 -2.0764 -0.9977 1147665 TimTec1_004330 Fc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)NC4CC4)sc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E19 compound treatment 11240.0 -40700.0 -2.36 9640.0 -33700.0 -2.55 -3.4681 -0.9992 1323101 TimTec1_004331 COC(=O)c1c(CC=C(C)C)c(C)nc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E20 compound treatment 33880.0 -18000.0 -1.04 24520.0 -18800.0 -1.42 -1.7442 -0.9884 3212392 TimTec1_004332 CC1CN=C(S1)N(Cc2ccccc2Cl)C(=O)Nc3cccc(Cl)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E21 compound treatment 56160.0 4270.0 0.25 46120.0 2800.0 0.21 0.3247 0.9971 3085349 TimTec1_004333 S=c1[nH]nc(Cc2ccccc2)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E22 compound treatment 29200.0 -22700.0 -1.31 23280.0 -20000.0 -1.52 -2.0023 -0.9975 1488335 TimTec1_004334 O=C(CSc1ncnc2[nH]cnc12)c3ccc4ccccc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E23 mock treatment 56200.0 4310.0 0.25 42440.0 -880.0 -0.07 0.1294 0.5008 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 E24 mock treatment 52200.0 308.0 0.02 47120.0 3800.0 0.29 0.216 0.7495 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F01 compound treatment 31800.0 -20100.0 -1.16 23680.0 -19600.0 -1.49 -1.8744 -0.9927 3085351 TimTec1_004335 Cc1ccnc(NC(=O)c2cccs2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F02 compound treatment 55280.0 3390.0 0.2 37280.0 -6040.0 -0.46 -0.1845 -0.3708 3085353 TimTec1_004336 CSc1ncc(F)c(n1)N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F03 compound treatment 14640.0 -37300.0 -2.16 8560.0 -34800.0 -2.63 -3.3867 -0.9952 3212393 TimTec1_004337 CCC(Sc1ccccn1)C(=O)Nc2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F04 compound treatment 55040.0 3150.0 0.18 38360.0 -4960.0 -0.38 -0.1365 -0.3271 3084406 TimTec1_004338 Nc1ccc(OCCOc2ccc(N)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F05 compound treatment 40400.0 -11500.0 -0.67 34760.0 -8560.0 -0.65 -0.929 -0.9999 1262298 TimTec1_004339 Fc1ccc(CNC(=O)C2CN(C(=O)C2)c3ccc(F)cc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F06 compound treatment 44560.0 -7330.0 -0.42 29560.0 -13800.0 -1.04 -1.0369 -0.9218 3212394 TimTec1_004340 CN(CC(COc1ccccc1)OC(=O)c2ccc(Cl)cc2)C3=NS(=O)(=O)c4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F07 compound treatment 40560.0 -11300.0 -0.66 31320.0 -12000.0 -0.91 -1.1066 -0.9873 1118159 TimTec1_004341 Cc1ccc(OCCN)c(Br)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F08 compound treatment 47440.0 -4450.0 -0.26 33880.0 -9440.0 -0.71 -0.6877 -0.9052 1694465 TimTec1_004342 COc1ccc(cc1)c2nn(CO)c(=S)n2c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F09 compound treatment 53840.0 1950.0 0.11 43040.0 -280.0 -0.02 0.0648 0.5644 3084411 TimTec1_004343 O=S1(=O)N=C(N2CCNCC2)c3ccccc31 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F10 compound treatment 38120.0 -13800.0 -0.8 20200.0 -23100.0 -1.75 -1.8017 -0.9367 1406499 TimTec1_004344 Cc1cc(C)c(COC(=O)c2nonc2N)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F11 compound treatment 49480.0 -2410.0 -0.14 41800.0 -1520.0 -0.12 -0.1802 -0.9953 1497656 TimTec1_004345 CC1(C)CC(=O)C(C(O)c2ccccc2)C(C)(C)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F12 compound treatment 42520.0 -9370.0 -0.54 30760.0 -12600.0 -0.95 -1.0562 -0.9647 3084413 TimTec1_004346 O=C(CSc1nnc(o1)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F13 compound treatment 40960.0 -10900.0 -0.63 38040.0 -5280.0 -0.4 -0.7305 -0.9753 1560213 TimTec1_004347 Clc1cccc(NC(=O)NC2CCN(C2)C3CCCCC3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F14 compound treatment 16360.0 -35500.0 -2.06 16160.0 -27200.0 -2.06 -2.9094 -1.0 3084415 TimTec1_004348 Cc1cn(C(=O)c2ccc(Cl)cc2Cl)c(C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F15 compound treatment 35520.0 -16400.0 -0.95 30680.0 -12600.0 -0.96 -1.3473 -1.0 1406332 TimTec1_004349 O=C(CSc1nc2ccc(NC(=O)C3CCCCC3)cc2s1)NCC4CCCO4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F16 compound treatment 43960.0 -7930.0 -0.46 33400.0 -9920.0 -0.75 -0.8559 -0.9722 3212395 TimTec1_004350 O=C1C2C(C3=C(CCCC3=O)N=C2c4ccccc14)c5cccs5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F17 compound treatment 40960.0 -10900.0 -0.63 31080.0 -12200.0 -0.93 -1.103 -0.9828 1570773 TimTec1_004351 CC(C)(C)Nc1nc(NC(C)(C)C)nc(n1)N2CCNCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F18 compound treatment 41680.0 -10200.0 -0.59 32640.0 -10700.0 -0.81 -0.99 -0.9882 1621338 TimTec1_004352 O=C(CSc1nc2ccccc2[nH]1)C3CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F19 compound treatment 51360.0 -533.0 -0.03 37520.0 -5800.0 -0.44 -0.3323 -0.7549 1630047 TimTec1_004353 O=S1(=O)CCC(C1)N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F20 compound treatment 57920.0 6030.0 0.35 44600.0 1280.0 0.1 0.3154 0.8704 1536902 TimTec1_004354 Cc1ccc(cc1)C(=O)C2C(=O)OC(=CC2=O)c3ccc(C)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F21 compound treatment 55320.0 3430.0 0.2 41840.0 -1480.0 -0.11 0.0612 0.2684 1248516 TimTec1_004355 Nc1nnc(SCC(=O)N2CCCCC2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F22 compound treatment 26800.0 -25100.0 -1.45 26400.0 -16900.0 -1.28 -1.9336 -0.998 3084420 TimTec1_004356 O=c1/c(=C\c2ccncc2)/sc3nc4ccccc4n13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F23 mock treatment 61520.0 9630.0 0.56 46280.0 2960.0 0.22 0.5529 0.9197 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 F24 mock treatment 53720.0 1830.0 0.11 46680.0 3360.0 0.25 0.2547 0.9246 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G01 compound treatment 50400.0 -1490.0 -0.09 41560.0 -1760.0 -0.13 -0.1553 -0.9781 1052156 TimTec1_004357 O=S(=O)(Nc1ccccn1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G02 compound treatment 47720.0 -4170.0 -0.24 34640.0 -8680.0 -0.66 -0.6355 -0.9078 1455699 TimTec1_004358 CC1(C)CC(CC(C)(C)N1)NC(=O)c2ccc(o2)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G03 compound treatment 33880.0 -18000.0 -1.04 19160.0 -24200.0 -1.83 -2.0311 -0.9646 3084422 TimTec1_004359 CCc1ccc2oc(nc2c1)c3cc(/N=C\c4ccccc4O)ccc3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G04 compound treatment 40800.0 -11100.0 -0.64 34720.0 -8600.0 -0.65 -0.9147 -1.0 3212396 TimTec1_004360 CSc1nsc(SC)c1NC(=O)Nc2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G05 compound treatment 50360.0 -1530.0 -0.09 33840.0 -9480.0 -0.72 -0.5702 -0.7886 3084424 TimTec1_004361 O=C(CCCCN1CCCCC1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G06 compound treatment 48880.0 -3010.0 -0.17 34800.0 -8520.0 -0.64 -0.5794 -0.8673 3212397 TimTec1_004362 FC(F)(F)C(NC(=O)c1ccccc1)(N2CCOCC2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G07 compound treatment 41360.0 -10500.0 -0.61 26280.0 -17000.0 -1.29 -1.3435 -0.9416 1644204 TimTec1_004363 CC(C)Nc1nc(Cl)nc(NC(C)(C)CO)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G08 compound treatment 48360.0 -3530.0 -0.2 38520.0 -4800.0 -0.36 -0.4016 -0.9631 1320611 TimTec1_004364 O=C(Nc1ccccn1)c2cccc(c2)N3C(=O)CCC3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G09 compound treatment 49320.0 -2570.0 -0.15 39920.0 -3400.0 -0.26 -0.2874 -0.9663 1019380 TimTec1_004365 C(N1CCCCC1)c2c[nH]c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G10 compound treatment 49520.0 -2370.0 -0.14 41840.0 -1480.0 -0.11 -0.1764 -0.9948 1557179 TimTec1_004366 OC(=O)CCn1c2ccccc2c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G11 compound treatment 31160.0 -20700.0 -1.2 27360.0 -16000.0 -1.21 -1.7036 -1.0 1693338 TimTec1_004367 COc1ccc(cc1)c2ncccc2O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G12 compound treatment 41440.0 -10500.0 -0.61 33080.0 -10200.0 -0.78 -0.9763 -0.9925 1612647 TimTec1_004368 NNC(=O)c1ccc(OCC(O)CO)cc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G13 compound treatment 31320.0 -20600.0 -1.19 23680.0 -19600.0 -1.49 -1.894 -0.994 1723169 TimTec1_004369 CCN(CC)c1ccc(Nc2cc(C)c(C#N)c3nc4ccccc4n23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G14 compound treatment 47360.0 -4530.0 -0.26 38320.0 -5000.0 -0.38 -0.4533 -0.9841 3084439 TimTec1_004370 N/C(=N\O)/c1cccc(n1)\C(=N\O)\N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G15 compound treatment 47280.0 -4610.0 -0.27 35080.0 -8240.0 -0.62 -0.63 -0.9284 3212398 TimTec1_004371 Cn1c2N(CC(=O)c2c(=O)n(C)c1=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G16 compound treatment 42440.0 -9450.0 -0.55 29200.0 -14100.0 -1.07 -1.143 -0.9518 3084441 TimTec1_004372 C(Sc1nnc(SCc2ccccn2)s1)c3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G17 compound treatment 30120.0 -21800.0 -1.26 24920.0 -18400.0 -1.39 -1.8768 -0.9988 3212399 TimTec1_004373 Fc1ccc(cc1)c2cc(nc(SCC(=O)Oc3ccccc3)c2C#N)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G18 compound treatment 50920.0 -973.0 -0.06 36560.0 -6760.0 -0.51 -0.4017 -0.7803 1717375 TimTec1_004374 O=C(CCSc1nccn1Cc2ccccc2)NC3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G19 compound treatment 44720.0 -7170.0 -0.42 38240.0 -5080.0 -0.38 -0.5657 -0.9992 3084443 TimTec1_004375 Cc1cc(C)nc(SCC(=O)c2c(N)no[n+]2[O-])n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G20 compound treatment 49280.0 -2610.0 -0.15 31760.0 -11600.0 -0.88 -0.7258 -0.8173 3212400 TimTec1_004376 CC1CN=C(S1)N(C(=O)Nc2ccc(Cl)cc2)c3cccc(C)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G21 compound treatment 53440.0 1550.0 0.09 40800.0 -2520.0 -0.19 -0.0715 -0.3391 3084445 TimTec1_004377 CC(C)C(=O)NC1=NC2C(N=CN2C3CC(O)C(CO)O3)C(=N1)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G22 compound treatment 52600.0 708.0 0.04 46160.0 2840.0 0.21 0.181 0.827 3212401 TimTec1_004378 O=C1CN(C=NN1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G23 mock treatment 53400.0 1510.0 0.09 43360.0 40.0 0.0 0.0639 0.7312 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 G24 mock treatment 54440.0 2550.0 0.15 41240.0 -2080.0 -0.16 -0.007 -0.0323 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H01 compound treatment 45520.0 -6370.0 -0.37 29240.0 -14100.0 -1.07 -1.0147 -0.8996 1333222 TimTec1_004379 COc1ccccc1NCn2c(=O)sc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H02 compound treatment 49600.0 -2290.0 -0.13 32880.0 -10400.0 -0.79 -0.6527 -0.8145 1378323 TimTec1_004380 CSc1ncc(F)c(n1)N(CCO)CCO 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H03 compound treatment 38600.0 -13300.0 -0.77 26720.0 -16600.0 -1.26 -1.4331 -0.9724 1426454 TimTec1_004381 O=C(CNC(=O)C(c1ccccc1)c2ccccc2)NC3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H04 compound treatment 45200.0 -6690.0 -0.39 30920.0 -12400.0 -0.94 -0.9379 -0.9235 3084448 TimTec1_004382 Cc1ccc(cc1)P(=O)(C)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H05 compound treatment 30920.0 -21000.0 -1.22 25320.0 -18000.0 -1.36 -1.8226 -0.9984 1325975 TimTec1_004383 O=c1n(CCc2ccccn2)nc(c3ccccc3)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H06 compound treatment 41960.0 -9930.0 -0.58 26080.0 -17200.0 -1.3 -1.3297 -0.9323 1363120 TimTec1_004384 OC(COc1ccccc1)CS(=O)(=O)c2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H07 compound treatment 39480.0 -12400.0 -0.72 34040.0 -9280.0 -0.7 -1.0052 -0.9999 1512838 TimTec1_004385 CSCCC1NC(=S)N(Cc2ccccc2)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H08 compound treatment 19680.0 -32200.0 -1.87 15680.0 -27600.0 -2.09 -2.7991 -0.9984 1461248 TimTec1_004386 Fc1ccc(cc1)C(=O)Nc2ccc3C(=O)OCc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H09 compound treatment 25920.0 -26000.0 -1.5 23600.0 -19700.0 -1.49 -2.1195 -1.0 1264638 TimTec1_004387 Oc1ccc2occ(C(=O)c3cccs3)c2c1CN4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H10 compound treatment 41920.0 -9970.0 -0.58 33760.0 -9560.0 -0.72 -0.9202 -0.9938 1248397 TimTec1_004388 CCSc1nc2ccccc2n1CC(=O)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H11 compound treatment 44960.0 -6930.0 -0.4 36160.0 -7160.0 -0.54 -0.6672 -0.9891 3084452 TimTec1_004389 O=C(OC[C@@H]1CCCN2CCCCC12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H12 compound treatment 45200.0 -6690.0 -0.39 31800.0 -11500.0 -0.87 -0.8908 -0.9334 3212402 TimTec1_004390 CCOC(=O)c1[nH]c(COC(=O)C)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H13 compound treatment 37320.0 -14600.0 -0.84 29240.0 -14100.0 -1.07 -1.3506 -0.9933 1294077 TimTec1_004391 COc1ccc(cc1)C(=O)c2coc3ccc(OC)cc3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H14 compound treatment 41760.0 -10100.0 -0.59 29760.0 -13600.0 -1.03 -1.1409 -0.9649 1370478 TimTec1_004392 Fc1cc2c(=O)cc[nH]c2cc1N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H15 compound treatment 50400.0 -1490.0 -0.09 39040.0 -4280.0 -0.32 -0.2902 -0.8655 1351428 TimTec1_004393 Cc1ccc(cc1)S(=O)(=O)N2CC(=O)N(O)C2c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H16 compound treatment 39840.0 -12100.0 -0.7 29720.0 -13600.0 -1.03 -1.2217 -0.9821 3084456 TimTec1_004394 FC(F)(F)c1ccc2sc(S)nc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H17 compound treatment 46120.0 -5770.0 -0.33 37720.0 -5600.0 -0.42 -0.5362 -0.9931 1715297 TimTec1_004395 N#CC(CCN1CCNCC1)(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H18 compound treatment 44040.0 -7850.0 -0.45 30520.0 -12800.0 -0.97 -1.0068 -0.9406 1355787 TimTec1_004396 OCCN(CCO)C(=O)CCc1[nH]c2ccccc2c1Sc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H19 compound treatment 50040.0 -1850.0 -0.11 43920.0 600.0 0.05 -0.0438 -0.3756 3212474 TimTec1_004397 Clc1ccc(NC(=O)CSC2=NC(=O)C(C(=O)N2)c3ccccc3)nc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H20 compound treatment 52280.0 388.0 0.02 40000.0 -3320.0 -0.25 -0.1618 -0.6414 3084461 TimTec1_004398 CC1CNc2ccccc2N=C1N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H21 compound treatment 43920.0 -7970.0 -0.46 39880.0 -3440.0 -0.26 -0.5107 -0.9632 3212475 TimTec1_004399 S=c1[nH]cnc2n(CN3CCCCC3)cnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H22 compound treatment 53840.0 1950.0 0.11 43720.0 400.0 0.03 0.1012 0.8662 1451020 TimTec1_004400 OC1=C(C(=O)c2ccccc2)C3(O)N(C1=O)c4ccccc4OC3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H23 mock treatment 51400.0 -493.0 -0.03 50040.0 6720.0 0.51 0.3395 0.6664 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 H24 mock treatment 47080.0 -4810.0 -0.28 38560.0 -4760.0 -0.36 -0.4519 -0.992 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I01 compound treatment 57160.0 5270.0 0.31 34880.0 -8440.0 -0.64 -0.2359 -0.3332 3084463 TimTec1_004401 C/C(=N\N)/c1nnn(c1C)c2nonc2N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I02 compound treatment 56920.0 5030.0 0.29 35120.0 -8200.0 -0.62 -0.2329 -0.3397 1525911 TimTec1_004402 OP(=O)(CCc1ccccn1)CN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I03 compound treatment 4920.0 -47000.0 -2.72 3680.0 -39600.0 -3.0 -4.0461 -0.9988 1170438 TimTec1_004403 CCN(CC)S(=O)(=O)c1ccc(cc1)c2csc(Nc3cccc(OC)c3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I04 compound treatment 52720.0 828.0 0.05 36080.0 -7240.0 -0.55 -0.3536 -0.6428 1584075 TimTec1_004404 O=C(C1C2C1C(=O)C3OCC2O3)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I05 compound treatment 39520.0 -12400.0 -0.72 29920.0 -13400.0 -1.01 -1.2241 -0.9856 1217640 TimTec1_004405 CN(C)Cc1cc2ccccc2[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I06 compound treatment 36240.0 -15700.0 -0.91 21240.0 -22100.0 -1.67 -1.8231 -0.9587 1227632 TimTec1_004406 N#CCCn1c(nc2ccccc12)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I07 compound treatment 49120.0 -2770.0 -0.16 39400.0 -3920.0 -0.3 -0.3234 -0.9585 1733675 TimTec1_004407 Cc1ccc(cc1C)N2NC(=O)CC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I08 compound treatment 43480.0 -8410.0 -0.49 31640.0 -11700.0 -0.88 -0.9698 -0.9606 1603161 TimTec1_004408 COC(=O)c1ccc(NC(=O)COC(=O)c2cc3ccccc3o2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I09 compound treatment 46320.0 -5570.0 -0.32 28640.0 -14700.0 -1.11 -1.014 -0.8763 1037174 TimTec1_004409 CCOC(=O)c1cc(C(=O)OCC)c(C)nc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I10 compound treatment 49320.0 -2570.0 -0.15 32240.0 -11100.0 -0.84 -0.6984 -0.8199 1467402 TimTec1_004410 COc1ccc(NC(=O)CSc2ccc3ccccc3n2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I11 compound treatment 38120.0 -13800.0 -0.8 24800.0 -18500.0 -1.4 -1.5555 -0.9643 1668645 TimTec1_004411 O=C(Nc1cccc2ccccc12)OC3CCS(=O)(=O)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I12 compound treatment 27280.0 -24600.0 -1.43 17680.0 -25600.0 -1.94 -2.3807 -0.9885 3212476 TimTec1_004412 Cc1cc2/C(=C\c3ccc(Cl)c(Cl)c3)/OC(=O)c2c(=S)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I13 compound treatment 37880.0 -14000.0 -0.81 29800.0 -13500.0 -1.02 -1.2977 -0.9934 1917148 TimTec1_004413 O=c1[nH]c2ccc(/N=C/c3ccc(C#Cc4ccccc4)cc3)cc2o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I14 compound treatment 49320.0 -2570.0 -0.15 36680.0 -6640.0 -0.5 -0.4608 -0.879 1236087 TimTec1_004414 O=C(C1CN2CCC1CC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I15 compound treatment 48720.0 -3170.0 -0.18 40680.0 -2640.0 -0.2 -0.2713 -0.9991 1912326 TimTec1_004415 CCOC(=O)C(C#N)C(=O)c1ccc(N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I16 compound treatment 51360.0 -533.0 -0.03 34960.0 -8360.0 -0.63 -0.4693 -0.7407 1609648 TimTec1_004416 CCCC(OC(=O)C)C#CCN1CCCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I17 compound treatment 37800.0 -14100.0 -0.82 34360.0 -8960.0 -0.68 -1.0569 -0.9957 3084472 TimTec1_004417 COC(=O)CSc1nsc(SCC(=O)OC)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I18 compound treatment 12400.0 -39500.0 -2.29 10520.0 -32800.0 -2.48 -3.3735 -0.9992 3212477 TimTec1_004418 CCC(Sc1nc(C)cc(C)n1)C(=O)Nc2sc3CCCCc3c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I19 compound treatment 30880.0 -21000.0 -1.22 31840.0 -11500.0 -0.87 -1.4753 -0.9863 1539203 TimTec1_004419 CCC1CCCCN1C(=O)c2cc3ccccc3oc2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I20 compound treatment 46360.0 -5530.0 -0.32 44160.0 840.0 0.06 -0.1817 -0.556 1728922 TimTec1_004420 Nc1nonc1C(=O)OCC(=O)N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I21 compound treatment 23360.0 -28500.0 -1.65 21560.0 -21800.0 -1.65 -2.3336 -1.0 1427907 TimTec1_004421 CCOc1ccc(OCC)c(c1)C(=O)C2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I22 compound treatment 48240.0 -3650.0 -0.21 38440.0 -4880.0 -0.37 -0.4108 -0.9651 1647970 TimTec1_004422 CCC(OC(=O)C)C#CCN1CCOCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I23 mock treatment 49800.0 -2090.0 -0.12 45400.0 2080.0 0.16 0.0256 0.1289 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 I24 mock treatment 46640.0 -5250.0 -0.3 41960.0 -1360.0 -0.1 -0.288 -0.8964 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J01 compound treatment 53320.0 1430.0 0.08 36960.0 -6360.0 -0.48 -0.2819 -0.5772 3084477 TimTec1_004423 Cn1nnnc1SCC(=O)NC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J02 compound treatment 42640.0 -9250.0 -0.54 28280.0 -15000.0 -1.14 -1.1841 -0.941 3084491 TimTec1_004424 Cn1c(=O)nc2n(c3cccc(c3)C(F)(F)F)c4ccccc4cc2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J03 compound treatment 50600.0 -1290.0 -0.07 38240.0 -5080.0 -0.38 -0.3249 -0.8292 3084494 TimTec1_004425 Oc1ccccc1C(=O)N2N=C(CC2(O)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J04 compound treatment 26320.0 -25600.0 -1.48 19560.0 -23800.0 -1.8 -2.3194 -0.9954 1706033 TimTec1_004426 OC(=O)c1cccc(NC(=O)CC(=O)c2ccccc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J05 compound treatment 36400.0 -15500.0 -0.9 26440.0 -16900.0 -1.28 -1.5382 -0.9851 1279425 TimTec1_004427 CCCC(=O)Nc1nnc(Cc2ccc(Cl)cc2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J06 compound treatment 31360.0 -20500.0 -1.19 20000.0 -23300.0 -1.77 -2.0894 -0.9816 1425542 TimTec1_004428 Fc1ccc(NC(=O)C2C3C2C4CCC3C4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J07 compound treatment 43200.0 -8690.0 -0.5 29520.0 -13800.0 -1.04 -1.0947 -0.944 1301943 TimTec1_004429 Cc1[nH]c(=S)c(C#N)c(C)c1CC(=O)c2ccc(Br)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J08 compound treatment 40880.0 -11000.0 -0.64 29960.0 -13400.0 -1.01 -1.1662 -0.9753 1313319 TimTec1_004430 COc1ccc(NC(=O)CC2SCCNC2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J09 compound treatment 24800.0 -27100.0 -1.57 16440.0 -26900.0 -2.03 -2.5487 -0.9918 1169823 TimTec1_004431 CCN(CC)c1nc(Nc2ccccc2OC)nc(Nc3cc(C)ccc3C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J10 compound treatment 38840.0 -13100.0 -0.76 26320.0 -17000.0 -1.29 -1.4446 -0.9679 3084499 TimTec1_004432 Cc1ccc(cc1)n2c(SCC=C)nc3sc4CCCc4c3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J11 compound treatment 28800.0 -23100.0 -1.34 22400.0 -20900.0 -1.58 -2.0658 -0.9965 1249197 TimTec1_004433 CCOC(=O)N1CCc2[nH]c3ccccc3c2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J12 compound treatment 10120.0 -41800.0 -2.42 8160.0 -35200.0 -2.66 -3.5932 -0.9989 1223335 TimTec1_004434 COc1ccc(Cl)cc1NC(=O)CCN2CCN(CC2)c3ccccc3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J13 compound treatment 38240.0 -13700.0 -0.79 32160.0 -11200.0 -0.84 -1.1566 -0.9995 1680037 TimTec1_004435 O=c1cc(Nc2ccc(cc2)N3CCCCC3)[nH]c(=O)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J14 compound treatment 36640.0 -15300.0 -0.88 28400.0 -14900.0 -1.13 -1.4234 -0.9926 1142790 TimTec1_004436 Cc1ccc(cc1C)N(Cc2ccc(cc2)C(=O)N3CCOCC3)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J15 compound treatment 34360.0 -17500.0 -1.02 27760.0 -15600.0 -1.18 -1.5511 -0.9973 1406310 TimTec1_004437 CCCNc1nc(NC2CCCCC2)nc(OC(C)C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J16 compound treatment 41120.0 -10800.0 -0.62 30800.0 -12500.0 -0.95 -1.1114 -0.9795 3212719 TimTec1_004438 CCC(=O)NC(Nc1sc2CCCCc2c1C(=O)N)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J17 compound treatment 46080.0 -5810.0 -0.34 39120.0 -4200.0 -0.32 -0.4629 -0.9996 1448396 TimTec1_004439 CC(C)C(NC(=O)C(c1ccccc1)c2ccccc2)C(=O)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J18 compound treatment 36400.0 -15500.0 -0.9 30720.0 -12600.0 -0.95 -1.3091 -0.9995 1655510 TimTec1_004440 Cc1ccccc1Nc2nc(Nc3ccccc3C)nc(Sc4nccn4C)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J19 compound treatment 57080.0 5190.0 0.3 41800.0 -1520.0 -0.12 0.1312 0.4076 1576794 TimTec1_004441 CC(=O)N(Cc1ccc(cc1)S(=O)(=O)N)C2CC(=O)N(C2=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J20 compound treatment 53240.0 1350.0 0.08 41520.0 -1800.0 -0.14 -0.0411 -0.262 1667869 TimTec1_004442 Cc1ccccc1OCc2nnc(SCCC(=O)O)n2Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J21 compound treatment 49120.0 -2770.0 -0.16 38200.0 -5120.0 -0.39 -0.3876 -0.924 3212720 TimTec1_004443 OCCCc1nnc(S)n1CC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J22 compound treatment 48200.0 -3690.0 -0.21 38840.0 -4480.0 -0.34 -0.3911 -0.9753 3212721 TimTec1_004444 COc1ccc(/C=N/c2ccc3[nH]c(=O)[nH]c3c2)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J23 mock treatment 48960.0 -2930.0 -0.17 38920.0 -4400.0 -0.33 -0.3556 -0.9512 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 J24 mock treatment 44920.0 -6970.0 -0.4 36480.0 -6840.0 -0.52 -0.6518 -0.9925 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K01 compound treatment 3600.0 -48300.0 -2.8 800.0 -42500.0 -3.22 -4.2543 -0.9976 3084505 TimTec1_004445 O=C(OCCSC1=NS(=O)(=O)c2ccccc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K02 compound treatment 47280.0 -4610.0 -0.27 34880.0 -8440.0 -0.64 -0.6407 -0.9252 3084507 TimTec1_004446 Cc1cc(C)c(C#N)c(SCC(=O)OC=C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K03 compound treatment 34280.0 -17600.0 -1.02 17400.0 -25900.0 -1.96 -2.1089 -0.9536 1649077 TimTec1_004447 O=C1OC2(CCCCC2)C(=C1)NCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K04 compound treatment 32240.0 -19700.0 -1.14 20720.0 -22600.0 -1.71 -2.0148 -0.9804 3212722 TimTec1_004448 CC1=NN(C(=O)c2ccc(Cl)cc2)C(C)(O)C1CC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K05 compound treatment 23680.0 -28200.0 -1.63 17520.0 -25800.0 -1.95 -2.5367 -0.9961 3212723 TimTec1_004449 COc1ccc(/C=N/C2(CC3CC4CC(C3)C2)C4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K06 compound treatment 34240.0 -17700.0 -1.02 27640.0 -15700.0 -1.19 -1.5624 -0.9973 1472188 TimTec1_004450 CCC(C)(N1CCC1=O)C(=O)Nc2cccc(C)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K07 compound treatment 36840.0 -15100.0 -0.87 25680.0 -17600.0 -1.34 -1.5608 -0.9787 3212724 TimTec1_004451 Cc1cccc2oc(nc12)c3ccc(/N=C/c4cc(ccc4O)C(=O)O)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K08 compound treatment 44400.0 -7490.0 -0.43 27520.0 -15800.0 -1.2 -1.1526 -0.9059 1385208 TimTec1_004452 Cc1ccc(C)c(c1)S(=O)(=O)n2ccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K09 compound treatment 37000.0 -14900.0 -0.86 25720.0 -17600.0 -1.33 -1.5521 -0.9779 1562045 TimTec1_004453 CN(c1c(C)n(C)n(c2ccccc2)c1=O)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K10 compound treatment 45680.0 -6210.0 -0.36 27760.0 -15600.0 -1.18 -1.0873 -0.8829 3084514 TimTec1_004454 Cc1cccc(NC(=O)c2cc(ccc2Cl)N3C(=O)C=CC3=O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K11 compound treatment 37640.0 -14300.0 -0.83 19520.0 -23800.0 -1.8 -1.8578 -0.9374 3212887 TimTec1_004455 CC(C)CN(C(=O)Nc1ccccc1)C2=NCC(C)S2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K12 compound treatment 33800.0 -18100.0 -1.05 19280.0 -24000.0 -1.82 -2.0279 -0.9657 1735032 TimTec1_004456 COc1ccccc1Nc2nc3CCCCc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K13 compound treatment 32520.0 -19400.0 -1.12 23400.0 -19900.0 -1.51 -1.8599 -0.9894 1256975 TimTec1_004457 CCCCS(=O)C1CCCCC1OC(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K14 compound treatment 19680.0 -32200.0 -1.87 12320.0 -31000.0 -2.35 -2.9789 -0.9936 1277459 TimTec1_004458 COC(=O)CNc1nc(Cl)nc(n1)N2CCC(C)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K15 compound treatment 32720.0 -19200.0 -1.11 23240.0 -20100.0 -1.52 -1.8602 -0.9881 1916082 TimTec1_004459 CC(=O)NC1=NN(C(S1)c2ccccc2)C(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K16 compound treatment 40520.0 -11400.0 -0.66 28280.0 -15000.0 -1.14 -1.2709 -0.9662 1664793 TimTec1_004460 Cc1ccc(cc1)N2C(=C(C(C3=C2CC(C)(C)CC3)c4ccc(Cl)cc4)C(=O)N)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K17 compound treatment 39880.0 -12000.0 -0.7 28240.0 -15100.0 -1.14 -1.2993 -0.9718 1554613 TimTec1_004461 CSc1nsc(SC)c1NC(=O)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K18 compound treatment 25440.0 -26500.0 -1.53 19400.0 -23900.0 -1.81 -2.364 -0.9966 1119521 TimTec1_004462 O=C1NC(Nc2c1sc(=S)n2c3ccccc3)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K19 compound treatment 17000.0 -34900.0 -2.02 19360.0 -24000.0 -1.81 -2.7119 -0.9985 1275123 TimTec1_004463 Nc1cc(nn1CC2CCCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K20 compound treatment 38040.0 -13900.0 -0.8 33360.0 -9960.0 -0.75 -1.1006 -0.9995 1161548 TimTec1_004464 Cc1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(c4ccccc4)c5ccccc5)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K21 compound treatment 37360.0 -14500.0 -0.84 31120.0 -12200.0 -0.92 -1.2484 -0.9989 1635937 TimTec1_004465 O=C(CSn1nnnc1c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K22 compound treatment 37320.0 -14600.0 -0.84 29200.0 -14100.0 -1.07 -1.3528 -0.9932 3212796 TimTec1_004466 FC(F)(F)c1c2CCc3ccccc3-c2nc4cc(nn14)C(=O)N5CCCC5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K23 mock treatment 41800.0 -10100.0 -0.58 37760.0 -5560.0 -0.42 -0.7111 -0.987 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 K24 mock treatment 41280.0 -10600.0 -0.61 33520.0 -9800.0 -0.74 -0.9593 -0.9957 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L01 compound treatment 25800.0 -26100.0 -1.51 17320.0 -26000.0 -1.97 -2.4606 -0.9915 1434454 TimTec1_004467 CC(=O)Nc1ccc(Nc2cc(C)c3ccccc3n2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L02 compound treatment 33440.0 -18500.0 -1.07 24440.0 -18900.0 -1.43 -1.7665 -0.9898 1330869 TimTec1_004468 CN1CC[C@@H]2[C@@H](C1)c3cc(C)ccc3N2C(=O)c4ccc(C)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L03 compound treatment 53720.0 1830.0 0.11 36600.0 -6720.0 -0.51 -0.2848 -0.5482 3084523 TimTec1_004469 Cc1cc(=O)oc2cc(OC(=O)CSC(=N)N)ccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L04 compound treatment 17440.0 -34500.0 -2.0 9960.0 -33400.0 -2.53 -3.197 -0.9932 1640717 TimTec1_004470 CCC(C(O)c1ccccc1)c2nc3ccccc3n2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L05 compound treatment 23760.0 -28100.0 -1.63 11960.0 -31400.0 -2.37 -2.831 -0.9832 3084525 TimTec1_004471 Clc1cccc(c1)C(=O)OCC(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L06 compound treatment 14720.0 -37200.0 -2.15 8200.0 -35100.0 -2.66 -3.4027 -0.9945 3212798 TimTec1_004472 CCSc1nc(c(C#N)c(=O)n1CC)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L07 compound treatment 47200.0 -4690.0 -0.27 28520.0 -14800.0 -1.12 -0.9844 -0.8539 1227993 TimTec1_004473 CC1(C)C2CCC3(C)OC(=O)N(N1c4ccccc4)C23C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L08 compound treatment 41000.0 -10900.0 -0.63 28560.0 -14800.0 -1.12 -1.2363 -0.9634 1742964 TimTec1_004474 CCOC(=O)N1CCN(CC1)C(=S)NC(=O)c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L09 compound treatment 43560.0 -8330.0 -0.48 35720.0 -7600.0 -0.58 -0.7481 -0.9962 1439010 TimTec1_004475 COc1ccc(CCNC(=O)C2C(C3CC2C=C3)C(=O)O)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L10 compound treatment 42240.0 -9650.0 -0.56 28840.0 -14500.0 -1.1 -1.1705 -0.9512 3084528 TimTec1_004476 CC1(C)CC(NC(=O)C(F)(F)F)C(NC(=O)C(F)(F)F)C(C)(C)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L11 compound treatment 33360.0 -18500.0 -1.07 22400.0 -20900.0 -1.58 -1.879 -0.9821 3212799 TimTec1_004477 NC(=O)/C(=N/O)/C1=NC2(CCCCC2)Cc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L12 compound treatment 36440.0 -15500.0 -0.9 24920.0 -18400.0 -1.39 -1.6179 -0.9772 1441377 TimTec1_004478 Clc1ccc(cc1)c2ccc(o2)C(=S)N3CCN(CC3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L13 compound treatment 46520.0 -5370.0 -0.31 31240.0 -12100.0 -0.91 -0.8667 -0.8973 1208093 TimTec1_004479 CN(C)CCOC(=O)C1(CC2c3ccccc3C1c4ccccc24)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L14 compound treatment 46960.0 -4930.0 -0.29 30320.0 -13000.0 -0.98 -0.8979 -0.8763 3084551 TimTec1_004480 CCOC(=O)c1c(O)c(Cl)c(C)[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L15 compound treatment 16480.0 -35400.0 -2.05 11160.0 -32200.0 -2.43 -3.1721 -0.9964 1150863 TimTec1_004481 CCOC(=O)c1c(C)c([nH]c1CN2CCOCC2)C(=O)OCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L16 compound treatment 42160.0 -9730.0 -0.56 28080.0 -15200.0 -1.15 -1.2144 -0.9458 3212800 TimTec1_004482 CC(=O)N1N=C(CC1c2ccc(F)cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L17 compound treatment 44760.0 -7130.0 -0.41 36320.0 -7000.0 -0.53 -0.6669 -0.9924 1417256 TimTec1_004483 OCCNC(=O)c1c2CCCCc2nc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L18 compound treatment 43600.0 -8290.0 -0.48 35720.0 -7600.0 -0.58 -0.7465 -0.996 1332505 TimTec1_004484 NNc1nnc2c3ccccc3[nH]c2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L19 compound treatment 44640.0 -7250.0 -0.42 32640.0 -10700.0 -0.81 -0.8688 -0.9535 1647319 TimTec1_004485 COc1ccc(cc1)C2OC(=O)Cc3cc(OC)c(OC)cc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L20 compound treatment 32080.0 -19800.0 -1.15 27280.0 -16000.0 -1.21 -1.6702 -0.9996 3084552 TimTec1_004486 O=c1nc(SCCOc2ccccc2)[nH]c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L21 compound treatment 51800.0 -92.5 -0.01 39600.0 -3720.0 -0.28 -0.2029 -0.7204 3212801 TimTec1_004487 CC(=O)Nc1ccc2nc(C)sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L22 compound treatment 47080.0 -4810.0 -0.28 41200.0 -2120.0 -0.16 -0.3106 -0.9656 1262531 TimTec1_004488 Nc1nonc1c2noc(n2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L23 mock treatment 59280.0 7390.0 0.43 41280.0 -2040.0 -0.15 0.1935 0.4252 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 L24 mock treatment 48120.0 -3770.0 -0.22 36520.0 -6800.0 -0.51 -0.5185 -0.9272 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M01 compound treatment 51880.0 -12.5 0.0 35680.0 -7640.0 -0.58 -0.4094 -0.708 3212802 TimTec1_004489 CCCc1c(C#N)c(N)[nH]c(=S)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M02 compound treatment 44360.0 -7530.0 -0.44 24400.0 -18900.0 -1.43 -1.3213 -0.8825 3084553 TimTec1_004490 N#Cc1ccc(nc1SCc2ccncc2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M03 compound treatment 36120.0 -15800.0 -0.91 26680.0 -16600.0 -1.26 -1.5368 -0.9876 1912735 TimTec1_004491 CCSc1nc(C)cc(COC)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M04 compound treatment 26520.0 -25400.0 -1.47 18440.0 -24900.0 -1.88 -2.3711 -0.9925 1677912 TimTec1_004492 OC(C1CCCN1Cc2ccccc2)(c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M05 compound treatment 34600.0 -17300.0 -1.0 23120.0 -20200.0 -1.53 -1.7896 -0.979 1303390 TimTec1_004493 CNC(=O)C(NS(=O)(=O)c1ccc(C)cc1)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M06 compound treatment 47000.0 -4890.0 -0.28 27560.0 -15800.0 -1.19 -1.044 -0.8514 1611737 TimTec1_004494 CC1CN(C)CC(C1)(OC(=O)C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M07 compound treatment 43200.0 -8690.0 -0.5 29720.0 -13600.0 -1.03 -1.084 -0.9459 1011962 TimTec1_004495 OC(=O)CCC(=O)Nc1ccc2ccccc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M08 compound treatment 38000.0 -13900.0 -0.8 22680.0 -20600.0 -1.56 -1.6739 -0.9524 1708192 TimTec1_004496 CCOC(=O)c1[nH]c(C)c(C(=O)C(C)C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M09 compound treatment 43120.0 -8770.0 -0.51 27160.0 -16200.0 -1.22 -1.2243 -0.9243 1647225 TimTec1_004497 CC1CCN(CC1)c2nc(nc(n2)N3CCC(C)CC3)N4CCC(C)CC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M10 compound treatment 27040.0 -24900.0 -1.44 21280.0 -22000.0 -1.67 -2.1978 -0.9973 3212803 TimTec1_004498 COc1cccc(OCCNC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M11 compound treatment 20760.0 -31100.0 -1.8 11520.0 -31800.0 -2.41 -2.9775 -0.9899 3084554 TimTec1_004499 Oc1ccccc1/C=N/c2nc[nH]n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M12 compound treatment 38440.0 -13500.0 -0.78 25920.0 -17400.0 -1.32 -1.4824 -0.9687 3212804 TimTec1_004500 CCSc1nsc(SCC)c1C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M13 compound treatment 42800.0 -9090.0 -0.53 27840.0 -15500.0 -1.17 -1.2011 -0.9349 3212805 TimTec1_004501 CSc1nnc2n(/N=C/c3cc4OCOc4cc3Br)cnn12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M14 compound treatment 52440.0 548.0 0.03 31120.0 -12200.0 -0.92 -0.6306 -0.6824 1631850 TimTec1_004502 O=c1[nH]cc(COCc2ccccc2)c(=O)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M15 compound treatment 43720.0 -8170.0 -0.47 32320.0 -11000.0 -0.83 -0.9236 -0.9642 1119024 TimTec1_004503 CC(C)(C)NC1=CC(=O)OC21CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M16 compound treatment 49160.0 -2730.0 -0.16 30680.0 -12600.0 -0.96 -0.7885 -0.8131 3212806 TimTec1_004504 COC(=O)c1cccc(NC(=O)COC(=O)CSc2nc(C)cc(C)n2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M17 compound treatment 23400.0 -28500.0 -1.65 12600.0 -30700.0 -2.33 -2.8115 -0.9859 3212807 TimTec1_004505 NC(=O)CSc1nsc(SCc2ccc(Cl)cc2)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M18 compound treatment 45000.0 -6890.0 -0.4 32960.0 -10400.0 -0.78 -0.8369 -0.951 1558723 TimTec1_004506 CC(=O)NC(Cc1ccc(F)cc1)C(=O)OCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M19 compound treatment 18360.0 -33500.0 -1.94 14080.0 -29200.0 -2.21 -2.9388 -0.9979 1121754 TimTec1_004507 CCOC(=O)c1cnn(CC2CCCCC2)c1N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M20 compound treatment 44160.0 -7730.0 -0.45 30600.0 -12700.0 -0.96 -0.9976 -0.9394 1392807 TimTec1_004508 O=C(NC(Cc1c[nH]c2ccccc12)C(=O)NC3CCCCC3)C(c4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M21 compound treatment 44120.0 -7770.0 -0.45 32800.0 -10500.0 -0.8 -0.8815 -0.9636 3084555 TimTec1_004509 CSc1nc2ccc(/N=C/c3ccc(Sc4nnnn4c5ccccc5)o3)cc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M22 compound treatment 40160.0 -11700.0 -0.68 30200.0 -13100.0 -0.99 -1.1829 -0.9829 1691433 TimTec1_004510 Clc1ccc(NC(=O)C2C3CCC=CCCC23)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M23 mock treatment 47040.0 -4850.0 -0.28 41760.0 -1560.0 -0.12 -0.2823 -0.9258 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 M24 mock treatment 50760.0 -1130.0 -0.07 37840.0 -5480.0 -0.41 -0.3397 -0.8089 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N01 compound treatment 34280.0 -17600.0 -1.02 23000.0 -20300.0 -1.54 -1.8092 -0.9801 3084556 TimTec1_004511 FC(F)(F)c1ccccc1/C=C\2/SC(=N)NC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N02 compound treatment 38400.0 -13500.0 -0.78 28160.0 -15200.0 -1.15 -1.3642 -0.9825 1558366 TimTec1_004512 O=C(N1CCCCCC1)c2cc3ccccc3c(=O)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N03 compound treatment 47720.0 -4170.0 -0.24 32800.0 -10500.0 -0.8 -0.734 -0.882 1395140 TimTec1_004513 Cc1ccc2[nH]c(SCC(=O)O)nc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N04 compound treatment 27920.0 -24000.0 -1.39 25280.0 -18000.0 -1.37 -1.9477 -1.0 3212808 TimTec1_004514 Clc1c(sc2ccccc12)C(=O)n3cccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N05 compound treatment 27680.0 -24200.0 -1.4 21920.0 -21400.0 -1.62 -2.1374 -0.9974 3084561 TimTec1_004515 Cc1nn(C(=O)Cc2ccc(Cl)cc2)c(C)c1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N06 compound treatment 43160.0 -8730.0 -0.51 31080.0 -12200.0 -0.93 -1.0129 -0.9595 1622238 TimTec1_004516 Nc1ccc(cc1F)c2nnn[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N07 compound treatment 18120.0 -33800.0 -1.96 12880.0 -30400.0 -2.3 -3.0129 -0.9967 3084563 TimTec1_004517 CCNc1nnc(CSc2nc3ccccc3s2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N08 compound treatment 25880.0 -26000.0 -1.51 20520.0 -22800.0 -1.73 -2.286 -0.9977 1261617 TimTec1_004518 CC(=C)CSC1=C(C#N)C(C)(C)C(C#N)C(=O)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N09 compound treatment 29400.0 -22500.0 -1.3 21480.0 -21800.0 -1.65 -2.0904 -0.9931 3212888 TimTec1_004519 COc1cccc(c1)C2C(=C(N)Oc3c2c(C)nn3c4ccccc4)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N10 compound treatment 33840.0 -18100.0 -1.05 24760.0 -18600.0 -1.4 -1.733 -0.9894 1151574 TimTec1_004520 COc1cccc(c1)N2C(=O)NC(=O)C(CCc3ccncc3)(CCc4ccncc4)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N11 compound treatment 41960.0 -9930.0 -0.58 28840.0 -14500.0 -1.1 -1.1819 -0.9548 3212889 TimTec1_004521 CCOC1CC(C)(C)NC(=S)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N12 compound treatment 37440.0 -14500.0 -0.84 29000.0 -14300.0 -1.08 -1.3586 -0.9919 1367122 TimTec1_004522 OC1CCN(C2CCCCC12)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N13 compound treatment 20160.0 -31700.0 -1.84 13360.0 -30000.0 -2.27 -2.9036 -0.9946 1402632 TimTec1_004523 CCCn1c(nc2ccccc12)c3nonc3N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N14 compound treatment 37840.0 -14100.0 -0.81 26200.0 -17100.0 -1.3 -1.492 -0.9749 1157736 TimTec1_004524 CCOC(=O)c1cc(C(=O)NC(C)c2ccccc2)c(C)[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N15 compound treatment 41120.0 -10800.0 -0.62 30920.0 -12400.0 -0.94 -1.105 -0.9803 1611714 TimTec1_004525 COC(=O)C(C(=O)OC)c1ccc(C#N)c(C#N)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N16 compound treatment 12120.0 -39800.0 -2.3 8680.0 -34600.0 -2.62 -3.4835 -0.9979 3212890 TimTec1_004526 COc1ccc(cc1)N(/N=C/2\Oc3ccc4c(C)cc(=O)oc4c3C2=O)C(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N17 compound treatment 22680.0 -29200.0 -1.69 18440.0 -24900.0 -1.88 -2.5285 -0.9986 1271644 TimTec1_004527 OC1(CSC2=C(C#N)C(CC(=O)N21)c3cccs3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N18 compound treatment 28560.0 -23300.0 -1.35 21560.0 -21800.0 -1.65 -2.1206 -0.9952 1486726 TimTec1_004528 CCCS(=O)(=O)c1c(C(=O)c2ccc(C)cc2)n3cccc(N)c3c1S(=O)(=O)CCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N19 compound treatment 46760.0 -5130.0 -0.3 35320.0 -8000.0 -0.61 -0.6385 -0.9464 3084570 TimTec1_004529 Cc1nnnn1CC(=O)Nc2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N20 compound treatment 42840.0 -9050.0 -0.52 34880.0 -8440.0 -0.64 -0.8226 -0.9952 1252602 TimTec1_004530 COc1ccc(Br)cc1S(=O)(=O)NCc2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N21 compound treatment 45080.0 -6810.0 -0.39 33120.0 -10200.0 -0.77 -0.825 -0.9515 3212891 TimTec1_004531 CCOC(=O)C1=C(OC(=C(C#N)C1c2ccc(F)cc2)N)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N22 compound treatment 46280.0 -5610.0 -0.33 32520.0 -10800.0 -0.82 -0.808 -0.9184 1565486 TimTec1_004532 COc1cc(Oc2ccccc2CC=C)nc(N)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N23 mock treatment 44000.0 -7890.0 -0.46 37720.0 -5600.0 -0.42 -0.6231 -0.9993 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 N24 mock treatment 53960.0 2070.0 0.12 41320.0 -2000.0 -0.15 -0.0223 -0.1158 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O01 compound treatment 20560.0 -31300.0 -1.82 10400.0 -32900.0 -2.49 -3.0456 -0.9879 1618653 TimTec1_004533 Cc1ccc(cc1C)C(=O)c2cccc(N)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O02 compound treatment 2840.0 -49100.0 -2.84 2760.0 -40600.0 -3.07 -4.1805 -0.9993 3212892 TimTec1_004534 COC(=O)c1c(C)[nH]c(C)c1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O03 compound treatment 40080.0 -11800.0 -0.68 29160.0 -14200.0 -1.07 -1.2418 -0.9765 3084586 TimTec1_004535 CSc1nnc2n(/N=C/c3c[nH]c4ccccc34)cnn12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O04 compound treatment 30760.0 -21100.0 -1.22 23720.0 -19600.0 -1.48 -1.9148 -0.9954 3212893 TimTec1_004536 NC(=O)[C@@H]1[C@@H](c2ccc(Cl)cc2)C1(C#N)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O05 compound treatment 39440.0 -12500.0 -0.72 27480.0 -15800.0 -1.2 -1.358 -0.9704 1780136 TimTec1_004537 CCOC(=O)c1c(C)cc(C)[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O06 compound treatment 43120.0 -8770.0 -0.51 34160.0 -9160.0 -0.69 -0.8497 -0.9883 1363495 TimTec1_004538 CN(Cn1nc(O)ccc1=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O07 compound treatment 8080.0 -43800.0 -2.54 4040.0 -39300.0 -2.97 -3.8973 -0.9969 3084613 TimTec1_004539 NC1=NN(CC1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O08 compound treatment 42280.0 -9610.0 -0.56 31840.0 -11500.0 -0.87 -1.0083 -0.9769 1493858 TimTec1_004540 COc1ccc(cc1OC)C2=C(N)C(=O)NC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O09 compound treatment 40880.0 -11000.0 -0.64 32120.0 -11200.0 -0.85 -1.0506 -0.9902 3212894 TimTec1_004541 Cc1ccccc1/C=N/N2C(=O)c3ccc4CCc5ccc(C2=O)c3c45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O10 compound treatment 20920.0 -31000.0 -1.79 16480.0 -26800.0 -2.03 -2.7055 -0.9981 1029950 TimTec1_004542 CN(C)c1ccc(cc1)C(=NO)c2ccc(cc2)N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O11 compound treatment 44960.0 -6930.0 -0.4 38200.0 -5120.0 -0.39 -0.5581 -0.9998 1641866 TimTec1_004543 Cc1cc(C)c(cc1S(=O)(=O)N)S(=O)(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O12 compound treatment 14240.0 -37700.0 -2.18 8400.0 -34900.0 -2.64 -3.4116 -0.9955 3212895 TimTec1_004544 O=C(CSc1ccccn1)Nc2sc3CCCCc3c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O13 compound treatment 48160.0 -3730.0 -0.22 38440.0 -4880.0 -0.37 -0.4141 -0.9675 3084617 TimTec1_004545 O=C(CSc1ncn[nH]1)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O14 compound treatment 48760.0 -3130.0 -0.18 38200.0 -5120.0 -0.39 -0.4024 -0.9402 1421449 TimTec1_004546 NC(=O)Cc1ccc(NC(=O)CCC(=O)O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O15 compound treatment 55560.0 3670.0 0.21 33680.0 -9640.0 -0.73 -0.3657 -0.4812 1919218 TimTec1_004547 OC(=O)CCCC(=O)Nc1cccc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O16 compound treatment 24960.0 -26900.0 -1.56 16840.0 -26500.0 -2.0 -2.5207 -0.9923 3084620 TimTec1_004548 FC(F)(F)c1cccc(c1)N2CCN(CC2)C(=S)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O17 compound treatment 32640.0 -19300.0 -1.12 24960.0 -18400.0 -1.39 -1.7714 -0.9941 1239543 TimTec1_004549 O=C(CSc1nc2ccccc2o1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O18 compound treatment 47200.0 -4690.0 -0.27 34760.0 -8560.0 -0.65 -0.6504 -0.9256 1529100 TimTec1_004550 CCn1cc(c(C#N)c1NC(=O)C)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O19 compound treatment 27400.0 -24500.0 -1.42 16720.0 -26600.0 -2.01 -2.4272 -0.9853 3084622 TimTec1_004551 Clc1ccc(OCCNC(=O)c2cccs2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O20 compound treatment 54680.0 2790.0 0.16 41560.0 -1760.0 -0.13 0.02 0.0955 1322941 TimTec1_004552 Cc1cc(C)n(NC2=CC(=O)CC(C)(C)C2)c(=O)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O21 compound treatment 52680.0 788.0 0.05 38400.0 -4920.0 -0.37 -0.2311 -0.6159 3212896 TimTec1_004553 CCN/C(=N/CC)/SC1CC(=O)N(C1=O)c2ccc(OCC)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O22 compound treatment 54440.0 2550.0 0.15 44600.0 1280.0 0.1 0.1729 0.9792 3084625 TimTec1_004554 Nc1nc(nc2c3ccccc3oc(=O)c12)c4cccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O23 mock treatment 51080.0 -813.0 -0.05 40840.0 -2480.0 -0.19 -0.166 -0.8579 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 O24 mock treatment 48440.0 -3450.0 -0.2 48160.0 4840.0 0.37 0.1176 0.2818 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P01 compound treatment 39560.0 -12300.0 -0.71 37640.0 -5680.0 -0.43 -0.8093 -0.9704 1465751 TimTec1_004555 O=C(Cc1ccccc1)Nc2ccc3oc(nc3c2)c4ccncc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P02 compound treatment 23680.0 -28200.0 -1.63 14600.0 -28700.0 -2.17 -2.693 -0.9901 1350858 TimTec1_004556 Cc1cccc(C)c1N2CCc3cn[nH]c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P03 compound treatment 29120.0 -22800.0 -1.32 18400.0 -24900.0 -1.89 -2.2668 -0.9847 1593678 TimTec1_004557 COc1ccc(CCC(O)C2(O)CCCCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P04 compound treatment 23360.0 -28500.0 -1.65 13840.0 -29500.0 -2.23 -2.7468 -0.9891 1664967 TimTec1_004558 Clc1ccc(NC(=O)CC2SCCNC2=O)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P05 compound treatment 39520.0 -12400.0 -0.72 29320.0 -14000.0 -1.06 -1.2562 -0.9819 1438867 TimTec1_004559 O=C1N(CC2CCCO2)C(=O)c3cc(ccc13)c4nc5ccccc5c(=O)o4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P06 compound treatment 36040.0 -15900.0 -0.92 28160.0 -15200.0 -1.15 -1.4609 -0.9939 1740022 TimTec1_004560 CC1CN(Cn2nc(c3ccccc3)n(CC=C)c2=S)CC(C)O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P07 compound treatment 38680.0 -13200.0 -0.77 30320.0 -13000.0 -0.98 -1.2371 -0.9923 1430817 TimTec1_004561 O=C(CSCc1ccccc1)Nc2nnc(Cc3ccccc3)s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P08 compound treatment 41360.0 -10500.0 -0.61 27480.0 -15800.0 -1.2 -1.2793 -0.9509 1573254 TimTec1_004562 CC(CN1CCNCC1)(NS(=O)(=O)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P09 compound treatment 41680.0 -10200.0 -0.59 28040.0 -15300.0 -1.16 -1.2362 -0.9516 1431707 TimTec1_004563 COc1cc2C(CC(=O)Nc3ccccc3)C(=O)N(N=C(C)c2cc1OC)C(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P10 compound treatment 33840.0 -18100.0 -1.05 24040.0 -19300.0 -1.46 -1.7715 -0.9867 1386480 TimTec1_004564 CC(C)CNC(=O)c1cccc(NC(=O)CC(C)C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P11 compound treatment 42600.0 -9290.0 -0.54 31040.0 -12300.0 -0.93 -1.038 -0.9663 3212897 TimTec1_004565 C=CC/N=C(\SCc1ccccc1)/N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P12 compound treatment 43320.0 -8570.0 -0.5 29080.0 -14200.0 -1.08 -1.1134 -0.9381 1213970 TimTec1_004566 CC(=O)Oc1coc2ccc3c(C)cc(=O)oc3c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P13 compound treatment 28280.0 -23600.0 -1.37 23000.0 -20300.0 -1.54 -2.055 -0.9983 1578888 TimTec1_004567 Clc1ccc(cc1)C(NC(=O)c2ccccc2Cl)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P14 compound treatment 34800.0 -17100.0 -0.99 28800.0 -14500.0 -1.1 -1.4774 -0.9986 1291706 TimTec1_004568 COC(=O)C1=C(C)NC(=C(C#N)C1c2cccnc2)S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P15 compound treatment 10160.0 -41700.0 -2.42 9480.0 -33800.0 -2.56 -3.521 -0.9996 3212898 TimTec1_004569 CCSc1cccc2cccnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P16 compound treatment 46360.0 -5530.0 -0.32 32440.0 -10900.0 -0.82 -0.809 -0.9154 1230586 TimTec1_004570 CC(=O)Nc1cc2c(C)cc(=O)oc2c3C(=O)COc31 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P17 compound treatment 41760.0 -10100.0 -0.59 32520.0 -10800.0 -0.82 -0.9932 -0.9868 3085776 TimTec1_004571 CCc1nnc(NC(=O)COC(=O)CSc2nc(cc(n2)c3ccccc3)c4ccccc4)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P18 compound treatment 14720.0 -37200.0 -2.15 12200.0 -31100.0 -2.36 -3.1886 -0.999 1673944 TimTec1_004572 Cc1nn2cc(nc2s1)c3ccc(N)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P19 compound treatment 47360.0 -4530.0 -0.26 38160.0 -5160.0 -0.39 -0.4619 -0.9813 3212899 TimTec1_004573 O=C(CSC1=NC(=O)C(Cc2ccccc2)C(=O)N1)NCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P20 compound treatment 41360.0 -10500.0 -0.61 38120.0 -5200.0 -0.39 -0.7098 -0.9775 3085777 TimTec1_004574 CCOC(=O)C1NCCc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P21 compound treatment 40720.0 -11200.0 -0.65 32920.0 -10400.0 -0.79 -1.0144 -0.9953 1311348 TimTec1_004575 CCC(=O)Oc1ccc2c3CCCc3c(=O)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P22 compound treatment 29040.0 -22900.0 -1.32 22480.0 -20800.0 -1.58 -2.0517 -0.9962 1265079 TimTec1_004576 COc1ccc2nc(C)c3CC(C)Oc3c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P23 mock treatment 47440.0 -4450.0 -0.26 41920.0 -1400.0 -0.11 -0.2573 -0.9228 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2075 P24 mock treatment 45880.0 -6010.0 -0.35 43080.0 -240.0 -0.02 -0.2592 -0.743 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A01 compound treatment 51080.0 9540.0 0.55 53720.0 13400.0 1.01 1.1085 0.9592 3212900 TimTec1_004577 Cc1n[nH]c(O)c1CCCOc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A02 compound treatment 12200.0 -29300.0 -1.7 13720.0 -26600.0 -2.01 -2.6253 -0.9965 3085778 TimTec1_004578 Cc1cc(Sc2ccccn2)c3ccccc3n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A03 compound treatment 35960.0 -5580.0 -0.32 40200.0 -111.0 -0.01 -0.2346 -0.7252 3212901 TimTec1_004579 [O-][n+]1onc2c(nnc(c3ccc(Cl)cc3)c12)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A04 compound treatment 51360.0 9820.0 0.57 40160.0 -151.0 -0.01 0.3942 0.6928 3085779 TimTec1_004580 NC(=O)CSc1nc(N)cc(N)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A05 compound treatment 35360.0 -6180.0 -0.36 40400.0 89.0 0.01 -0.2485 -0.6937 3212902 TimTec1_004581 Cc1ccc(cc1)c2cc(n3nc(cc3n2)C(=O)N4CCN(CC4)c5ccccc5)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A06 compound treatment 40480.0 -1060.0 -0.06 44920.0 4610.0 0.35 0.2032 0.5736 3085780 TimTec1_004582 COc1ccc(cc1OC)C2C(C(=O)NC(=C2C#N)O)[n+]3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A07 compound treatment 40960.0 -581.0 -0.03 41240.0 929.0 0.07 0.0259 0.3323 3211405 TimTec1_004583 CN1C(=O)CCN(C=O)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A08 compound treatment 45240.0 3700.0 0.21 37120.0 -3190.0 -0.24 -0.0193 -0.0597 1392481 TimTec1_004584 CCC(=O)Nc1c(C)c(Cl)c(C)nc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A09 compound treatment 50320.0 8780.0 0.51 41040.0 729.0 0.06 0.3987 0.7793 3211202 TimTec1_004585 CC(=O)NC1C(=O)NC(=NC1=O)SCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A10 compound treatment 44440.0 2900.0 0.17 45800.0 5490.0 0.42 0.4126 0.9206 1665015 TimTec1_004586 OC1=C(C(=O)c2ccccc2)C3(OC1=O)C(=O)NC(=O)NC3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A11 compound treatment 37080.0 -4460.0 -0.26 38000.0 -2310.0 -0.17 -0.3065 -0.9819 1224645 TimTec1_004587 COc1ccc(NC(=S)N(CC2CCCO2)CC3CCC=CC3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A12 compound treatment 40400.0 -1140.0 -0.07 39800.0 -511.0 -0.04 -0.0741 -0.9674 1534543 TimTec1_004588 Cc1nc(C(=O)N)c(N)n1CCO 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A13 compound treatment 40800.0 -741.0 -0.04 40120.0 -191.0 -0.01 -0.0406 -0.8957 3211203 TimTec1_004589 OC(=O)C1CCCCC1C(=O)Nc2ccc3[nH]c(=S)sc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A14 compound treatment 42160.0 619.0 0.04 38080.0 -2230.0 -0.17 -0.0941 -0.5449 1303334 TimTec1_004590 CCC1(C)OC(=O)N(CCc2c(C)[nH]c3ccccc23)C1(C)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A15 compound treatment 36560.0 -4980.0 -0.29 34040.0 -6270.0 -0.47 -0.5397 -0.9715 1738265 TimTec1_004591 CC1(C)CC(CC(C)(C)N1)N2C(=O)c3ccccc3C2(O)Cc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A16 compound treatment 45960.0 4420.0 0.26 40840.0 529.0 0.04 0.2093 0.8079 1544216 TimTec1_004592 O=C1Nc2nonc2NC(=C1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A17 compound treatment 46960.0 5420.0 0.31 43040.0 2730.0 0.21 0.3681 0.9794 1580828 TimTec1_004593 OCC1COC(=O)N1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A18 compound treatment 37200.0 -4340.0 -0.25 33400.0 -6910.0 -0.52 -0.5478 -0.9437 3211204 TimTec1_004594 CN1CCN(CC1)n/2c(cs\c2=N/c3ccccc3)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A19 compound treatment 10240.0 -31300.0 -1.81 10880.0 -29400.0 -2.23 -2.8576 -0.9948 3085781 TimTec1_004595 CCCn1c2ccccc2c3nnc(SCCNS(=O)(=O)c4ccccc4)nc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A20 compound treatment 43920.0 2380.0 0.14 44600.0 4290.0 0.32 0.327 0.9272 1295244 TimTec1_004596 COc1ccc(cc1OC)S(=O)(=O)NCCN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A21 compound treatment 3760.0 -37800.0 -2.19 6400.0 -33900.0 -2.57 -3.3629 -0.9969 1339032 TimTec1_004597 O=S1(=O)N=C(Oc2ccccc2)c3ccccc31 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A22 compound treatment 42880.0 1340.0 0.08 52240.0 11900.0 0.9 0.6933 0.765 3211205 TimTec1_004598 COc1ccc(cc1)n2c(=O)c3c4CC(OCc4sc3n5cnnc25)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A23 mock treatment 49280.0 7740.0 0.45 49960.0 9650.0 0.73 0.8335 0.9726 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 A24 mock treatment 53720.0 12200.0 0.71 62800.0 22500.0 1.7 1.7026 0.924 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B01 compound treatment 38120.0 -3420.0 -0.2 42480.0 2170.0 0.16 -0.0241 -0.0935 1180956 TimTec1_004599 CC(=O)Nc1cccc(C(=O)Oc2cccc(C)c2)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B02 compound treatment 39600.0 -1940.0 -0.11 45920.0 5610.0 0.42 0.2207 0.5025 3211206 TimTec1_004600 CC(C)OC(=O)COc1ccc2C(CC3(CC(C)(C)NC(=O)N3)Oc2c1)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B03 compound treatment 20760.0 -20800.0 -1.2 29240.0 -11100.0 -0.84 -1.4439 -0.9843 3085782 TimTec1_004601 O=S1(=O)N(Cc2ccccn2)c3cccc4cccc1c34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B04 compound treatment 37000.0 -4540.0 -0.26 47480.0 7170.0 0.54 0.1977 0.3278 3211207 TimTec1_004602 Cc1nn(c(N)c1c2ccc(Cl)cc2)c3nc4ccccc4[nH]3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B05 compound treatment 40080.0 -1460.0 -0.08 44240.0 3930.0 0.3 0.1504 0.4865 3085783 TimTec1_004603 OC1COC(NCCc2ccccc2)C(O)C1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B06 compound treatment 14040.0 -27500.0 -1.59 23680.0 -16600.0 -1.26 -2.0168 -0.9932 1409204 TimTec1_004604 N(c1ccccc1)c2nc3nonc3nc2Nc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B07 compound treatment 39480.0 -2060.0 -0.12 43440.0 3130.0 0.24 0.083 0.313 3211208 TimTec1_004605 FC(F)(F)C1(N=C(Nc2c1c(=O)[nH]c(=O)n2c3ccccc3)c4ccncc4)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B08 compound treatment 36320.0 -5220.0 -0.3 43800.0 3490.0 0.26 -0.0272 -0.0676 3085788 TimTec1_004606 CN1C2NCN(CCc3ccccc3)CC2C(=O)N(C)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B09 compound treatment 26680.0 -14900.0 -0.86 28840.0 -11500.0 -0.87 -1.2228 -1.0 3211209 TimTec1_004607 CCOc1ccc(Cn2nnc(n2)c3ccc(cc3)S(=O)(=O)C)cc1OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B10 compound treatment 34680.0 -6860.0 -0.4 43640.0 3330.0 0.25 -0.1029 -0.2186 1264288 TimTec1_004608 CN(NC1=C(C)CN(C2CCCCC2)C1=O)c3cccc(Cl)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B11 compound treatment 59120.0 17600.0 1.02 58360.0 18000.0 1.37 1.6862 0.9895 3211210 TimTec1_004609 OCC1OC(C(O)C1O)n2ccc(O)nc2=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B12 compound treatment 37760.0 -3780.0 -0.22 45200.0 4890.0 0.37 0.1068 0.2483 1629862 TimTec1_004610 OC1=C(Cc2ccccc2)CN(Cc3ccccc3)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B13 compound treatment 40360.0 -1180.0 -0.07 45600.0 5290.0 0.4 0.2347 0.5778 3211211 TimTec1_004611 CCCCc1ccc2nc3sc(cc3cc2c1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B14 compound treatment 30640.0 -10900.0 -0.63 35960.0 -4350.0 -0.33 -0.6795 -0.9539 3085792 TimTec1_004612 CC1(C)CC(=O)OC(C1)(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B15 compound treatment 17640.0 -23900.0 -1.38 20080.0 -20200.0 -1.53 -2.062 -0.9987 3211212 TimTec1_004613 CCCCS(=O)(=O)Nc1ccc(Cc2ccncc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B16 compound treatment 31520.0 -10000.0 -0.58 28200.0 -12100.0 -0.92 -1.0588 -0.9757 3211213 TimTec1_004614 FC(F)(F)C(=O)Nc1ccccc1C(=O)NCc2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B17 compound treatment 21480.0 -20100.0 -1.16 25760.0 -14600.0 -1.1 -1.6007 -0.9996 3085794 TimTec1_004615 CC(C)Nc1nc(nc(n1)n2ccnc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B18 compound treatment 38480.0 -3060.0 -0.18 43400.0 3090.0 0.23 0.0399 0.136 3085836 TimTec1_004616 O=CN1CCN(CC1)C(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B19 compound treatment 43760.0 2220.0 0.13 47320.0 7010.0 0.53 0.466 0.8537 3085838 TimTec1_004617 N(c1cccc2ccccc12)c3nc(nc(n3)n4ccnc4)n5ccnc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B20 compound treatment 35480.0 -6060.0 -0.35 39080.0 -1230.0 -0.09 -0.3142 -0.8648 1599768 TimTec1_004618 COC(=O)C1C(c2cc(OC)c(OC)cc2C1=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B21 compound treatment 46200.0 4660.0 0.27 45240.0 4930.0 0.37 0.4547 0.9874 3085840 TimTec1_004619 CC(C)(O)c1nnn(Cc2ccccc2)c1C(C)(C)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B22 compound treatment 12800.0 -28700.0 -1.67 14040.0 -26300.0 -1.99 -2.5836 -0.9961 1176863 TimTec1_004620 Cc1ncsc1C(=O)OC(C#N)c2cccc(Oc3ccccc3)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B23 mock treatment 43560.0 2020.0 0.12 45440.0 5130.0 0.39 0.3572 0.881 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 B24 mock treatment 48360.0 6820.0 0.4 49000.0 8690.0 0.66 0.7444 0.9703 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C01 compound treatment 43760.0 2220.0 0.13 44520.0 4210.0 0.32 0.3162 0.9203 3085842 TimTec1_004621 O=C(N/C(=C(\Sc1ccccn1)/c2ccccc2)/C(=O)N3CCOCC3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C02 compound treatment 30560.0 -11000.0 -0.64 38000.0 -2310.0 -0.17 -0.5736 -0.8693 3211214 TimTec1_004622 N#Cc1ccc(CSc2ncccn2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C03 compound treatment 25400.0 -16100.0 -0.94 29080.0 -11200.0 -0.85 -1.2624 -0.9989 1239016 TimTec1_004623 COc1ccc(C(=O)Nc2ccncc2)c(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C04 compound treatment 2560.0 -39000.0 -2.26 4280.0 -36000.0 -2.73 -3.5255 -0.9956 1306638 TimTec1_004624 COc1ccc(cc1OC)C(=O)CSC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C05 compound treatment 44280.0 2740.0 0.16 41920.0 1610.0 0.12 0.1983 0.9915 3085845 TimTec1_004625 CN1C(OC(=O)C)C(OC(=O)C)N(C)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C06 compound treatment 39600.0 -1940.0 -0.11 39160.0 -1150.0 -0.09 -0.1411 -0.992 1689037 TimTec1_004626 CC(=O)Nc1ccc(cc1)C2N3CCCN23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C07 compound treatment 40880.0 -661.0 -0.04 38360.0 -1950.0 -0.15 -0.1315 -0.862 1384622 TimTec1_004627 C=CCN1C(=O)CCNc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C08 compound treatment 43240.0 1700.0 0.1 42320.0 2010.0 0.15 0.1771 0.9778 1104469 TimTec1_004628 Cc1cc(Cl)nc(Cl)c1C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C09 compound treatment 10560.0 -31000.0 -1.79 16000.0 -24300.0 -1.84 -2.5705 -0.9999 1540410 TimTec1_004629 Brc1ccc(o1)C(=O)NC2C3CC4CC(C3)CC2C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C10 compound treatment 41960.0 419.0 0.02 44040.0 3730.0 0.28 0.2167 0.7651 3085848 TimTec1_004630 C1CCN2C(C3N4CCCCN34)N2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C11 compound treatment 18600.0 -22900.0 -1.33 23880.0 -16400.0 -1.24 -1.8193 -0.9994 1554188 TimTec1_004631 CCOC(=O)C1(CCN(CCOc2ccccc2)CC1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C12 compound treatment 32280.0 -9260.0 -0.54 35080.0 -5230.0 -0.4 -0.6594 -0.9888 1287126 TimTec1_004632 O=S(Cc1ccccc1)c2cc(Oc3ccccc3)ccc2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C13 compound treatment 15760.0 -25800.0 -1.49 20720.0 -19600.0 -1.48 -2.1048 -1.0 3211215 TimTec1_004633 O=C/1N2C(=C\C1=C/N3CCCCC3)C(=O)c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C14 compound treatment 37880.0 -3660.0 -0.21 40760.0 449.0 0.03 -0.126 -0.5863 1182870 TimTec1_004634 CCCc1cc2c3ccccc3oc(=O)c2c(NC(=O)C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C15 compound treatment 40800.0 -741.0 -0.04 41840.0 1530.0 0.12 0.0515 0.4169 1129282 TimTec1_004635 OC(=O)C1CC(=O)CCC1Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C16 compound treatment 21000.0 -20500.0 -1.19 23000.0 -17300.0 -1.31 -1.7681 -0.9988 1342925 TimTec1_004636 COc1nc(Cl)nc(n1)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C17 compound treatment 36200.0 -5340.0 -0.31 42480.0 2170.0 0.16 -0.1027 -0.2932 3211216 TimTec1_004637 OC(=O)c1ccc(/C=C/2\C(=O)NC(=O)N(C3CCCCC3)C2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C18 compound treatment 42440.0 899.0 0.05 41400.0 1090.0 0.08 0.0951 0.9755 1658196 TimTec1_004638 CCCCc1c(C)nc2ccc(Br)cc2c1SCCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C19 compound treatment 28760.0 -12800.0 -0.74 29880.0 -10400.0 -0.79 -1.0819 -0.9995 1175416 TimTec1_004639 CC(=O)NC(C)(C)COc1ccc(Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C20 compound treatment 44240.0 2700.0 0.16 50560.0 10200.0 0.78 0.6591 0.8329 1184099 TimTec1_004640 CC1(C)CC(CC(C)(C)N1)NC(=O)c2cc[nH]n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C21 compound treatment 42720.0 1180.0 0.07 45760.0 5450.0 0.41 0.3399 0.8131 3085855 TimTec1_004641 CC1=CC(C)(C)NC(=S)N1CC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C22 compound treatment 41440.0 -101.0 -0.01 43560.0 3250.0 0.25 0.1698 0.69 1171271 TimTec1_004642 O=C(NN1C(=O)c2ccccc2NC31CCCC3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C23 mock treatment 43640.0 2100.0 0.12 38600.0 -1710.0 -0.13 -0.0056 -0.0315 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 C24 mock treatment 46280.0 4740.0 0.27 44320.0 4010.0 0.3 0.4087 0.9988 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D01 compound treatment 46960.0 5420.0 0.31 49280.0 8970.0 0.68 0.7021 0.9386 1550109 TimTec1_004643 Cc1oc(C)c(C(=O)O)c1CN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D02 compound treatment 7800.0 -33700.0 -1.95 11800.0 -28500.0 -2.16 -2.9083 -0.9988 3085895 TimTec1_004644 Clc1ccc2oc3c(=O)oc(nc3c2c1)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D03 compound treatment 38800.0 -2740.0 -0.16 42720.0 2410.0 0.18 0.0166 0.0688 3211406 TimTec1_004645 O=C(NC(=O)c1ccccc1)OC2CCS(=O)(=O)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D04 compound treatment 39360.0 -2180.0 -0.13 45240.0 4930.0 0.37 0.1745 0.4429 3211407 TimTec1_004646 OC(=O)CC(NC(=O)C1(CC2CC3CC(C2)C1)C3)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D05 compound treatment 41840.0 299.0 0.02 40600.0 289.0 0.02 0.0277 0.9933 3085898 TimTec1_004647 CN(C1CC(C)(C)NC(C)(C)C1)C(=O)c2ccccc2C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D06 compound treatment 37880.0 -3660.0 -0.21 42960.0 2650.0 0.2 -0.0082 -0.0281 1913187 TimTec1_004648 CSc1sc(SC)c(C[n+]2ccccc2)c1C[n+]3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D07 compound treatment 31200.0 -10300.0 -0.6 36720.0 -3590.0 -0.27 -0.6159 -0.9361 3085900 TimTec1_004649 Cc1cc(NC(=O)NC(=O)c2cccs2)n[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D08 compound treatment 38600.0 -2940.0 -0.17 40440.0 129.0 0.01 -0.1136 -0.6655 1392952 TimTec1_004650 COc1ccc(cc1)N2CC(CC2=O)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D09 compound treatment 39600.0 -1940.0 -0.11 38800.0 -1510.0 -0.11 -0.1604 -1.0 3211408 TimTec1_004651 Cc1cn(CC(=O)NCCN)c(=O)[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D10 compound treatment 35360.0 -6180.0 -0.36 35240.0 -5070.0 -0.38 -0.5247 -0.9994 1692385 TimTec1_004652 CN(Nc1ccccc1)C2=C(CN(C3CCCCC3)C2=O)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D11 compound treatment 40560.0 -981.0 -0.06 39440.0 -871.0 -0.07 -0.0868 -0.9973 3211409 TimTec1_004653 Cc1cc(=O)[nH]c2nn(c(O)c12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D12 compound treatment 39200.0 -2340.0 -0.14 38800.0 -1510.0 -0.11 -0.1768 -0.9964 3085903 TimTec1_004654 CCOC(=O)C1=C(O)CN(C)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D13 compound treatment 35000.0 -6540.0 -0.38 33680.0 -6630.0 -0.5 -0.6229 -0.9904 3211410 TimTec1_004655 Cc1nn(C(=O)c2ccc(F)cc2)c(N)c1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D14 compound treatment 4160.0 -37400.0 -2.17 5880.0 -34400.0 -2.61 -3.3743 -0.9958 3085905 TimTec1_004656 CCn1ncc(Cl)c(Cl)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D15 compound treatment 2120.0 -39400.0 -2.28 2720.0 -37600.0 -2.85 -3.627 -0.9941 3211411 TimTec1_004657 COc1cc(C)c(cc1C(C)C)S(=O)(=O)Nc2ccc3nc(C)sc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D16 compound treatment 30280.0 -11300.0 -0.65 33600.0 -6710.0 -0.51 -0.8206 -0.9923 1577125 TimTec1_004658 CCOC(=O)CCCN1C(CCc2ccccc12)C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D17 compound treatment 20680.0 -20900.0 -1.21 26120.0 -14200.0 -1.07 -1.6142 -0.9983 3211412 TimTec1_004659 C1CC1Nc2nc(nc(n2)n3ccnc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D18 compound treatment 36920.0 -4620.0 -0.27 35960.0 -4350.0 -0.33 -0.4222 -0.9947 1034819 TimTec1_004660 CC(O)(c1ccccc1)C(C)(O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D19 compound treatment 38560.0 -2980.0 -0.17 42200.0 1890.0 0.14 -0.021 -0.0938 3211413 TimTec1_004661 O=S(=O)(Cc1ccccc1C#N)c2nc3cccnc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D20 compound treatment 42880.0 1340.0 0.08 43720.0 3410.0 0.26 0.2373 0.8807 3211414 TimTec1_004662 Oc1nc(Oc2cccc(c2)C(F)(F)F)cc(Oc3cccc(c3)C(F)(F)F)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D21 compound treatment 39640.0 -1900.0 -0.11 36920.0 -3390.0 -0.26 -0.2594 -0.9287 3085910 TimTec1_004663 CN(C(=O)CSc1nc(C)cc2COC(=O)c21)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D22 compound treatment 46680.0 5140.0 0.3 39960.0 -351.0 -0.03 0.1917 0.6415 3085911 TimTec1_004664 Cc1cc(=O)n(CNC(=O)c2ccco2)cn1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D23 mock treatment 45960.0 4420.0 0.26 42480.0 2170.0 0.16 0.2971 0.9769 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 D24 mock treatment 44280.0 2740.0 0.16 43640.0 3330.0 0.25 0.2904 0.9751 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E01 compound treatment 39720.0 -1820.0 -0.11 42920.0 2610.0 0.2 0.065 0.2904 3211415 TimTec1_004665 O/N=C(/C#N)\c1nc2ccccc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E02 compound treatment 39480.0 -2060.0 -0.12 43960.0 3650.0 0.28 0.1109 0.3684 1640993 TimTec1_004666 CCOc1ccc(NC(=O)CSc2nc3ccc(cc3s2)N4C(=O)c5ccccc5C4=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E03 compound treatment 43520.0 1980.0 0.11 43680.0 3370.0 0.26 0.2614 0.9349 1162299 TimTec1_004667 COc1ccc(cc1)c2nnc(NC(=O)CC(C)C)s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E04 compound treatment 33200.0 -8340.0 -0.48 38960.0 -1350.0 -0.1 -0.414 -0.8382 3085914 TimTec1_004668 Cc1nnc(SCC(=O)c2ccc(Cl)cc2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E05 compound treatment 37680.0 -3860.0 -0.22 33800.0 -6510.0 -0.49 -0.5067 -0.9361 3211416 TimTec1_004669 CN(C)C1N(N=C2N1S(=O)(=O)c3ccccc23)C(=O)c4ccc(C)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E06 compound treatment 37960.0 -3580.0 -0.21 38360.0 -1950.0 -0.15 -0.2511 -0.9861 3211417 TimTec1_004670 OC(=O)CSc1nnc(c2ccccc2Br)n1C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E07 compound treatment 33080.0 -8460.0 -0.49 34880.0 -5430.0 -0.41 -0.6373 -0.9962 1165665 TimTec1_004671 CC(C)N1C(=O)CCNc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E08 compound treatment 16680.0 -24900.0 -1.44 14600.0 -25700.0 -1.95 -2.3947 -0.989 3085950 TimTec1_004672 Clc1ccc(SCc2[nH]n(c3nc4ccccc4s3)c(=O)c2/C=N/Cc5ccco5)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E09 compound treatment 33280.0 -8260.0 -0.48 33080.0 -7230.0 -0.55 -0.7255 -0.9978 1675123 TimTec1_004673 COc1cc(CNC(=O)C2CCCC2)cc(OC)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E10 compound treatment 40560.0 -981.0 -0.06 39040.0 -1270.0 -0.1 -0.1082 -0.9685 1569434 TimTec1_004674 CCn1c(=N)n(CC(=O)c2ccc(Br)cc2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E11 compound treatment 37560.0 -3980.0 -0.23 37600.0 -2710.0 -0.21 -0.3082 -0.9983 3085953 TimTec1_004675 CC(C)(C)Nc1nc(=O)[nH]c(=O)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E12 compound treatment 32280.0 -9260.0 -0.54 36680.0 -3630.0 -0.27 -0.5738 -0.9517 3211418 TimTec1_004676 C[C@H]1C[C@H](C2C(=NNC2=O)C)N(N1c3ccccc3)C(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E13 compound treatment 18160.0 -23400.0 -1.35 24680.0 -15600.0 -1.18 -1.7945 -0.9977 1364377 TimTec1_004677 CN(Cc1ccccc1)Cc2c(O)ccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E14 compound treatment 33440.0 -8100.0 -0.47 34760.0 -5550.0 -0.42 -0.629 -0.9985 3211419 TimTec1_004678 O=C(C1CCCCC1)n2cnc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E15 compound treatment 34360.0 -7180.0 -0.42 34120.0 -6190.0 -0.47 -0.6256 -0.9982 3085956 TimTec1_004679 Cn1c(=O)c(C#N)c(c2ccccc2)n3cnnc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E16 compound treatment 33320.0 -8220.0 -0.48 30600.0 -9710.0 -0.74 -0.8566 -0.9779 3085958 TimTec1_004680 C=CCNC(=O)C#Cc1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E17 compound treatment 29680.0 -11900.0 -0.69 28760.0 -11600.0 -0.87 -1.1042 -0.9929 3211420 TimTec1_004681 CCOC(=O)n1ncc(C#N)c1N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E18 compound treatment 37920.0 -3620.0 -0.21 35920.0 -4390.0 -0.33 -0.3834 -0.9754 1935336 TimTec1_004682 CC(=O)OC1CC(C)(C)N(O)C(C)(C)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E19 compound treatment 36240.0 -5300.0 -0.31 35080.0 -5230.0 -0.4 -0.4972 -0.9921 1210397 TimTec1_004683 CC1CN(OC(O1)c2cccc(O)c2)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E20 compound treatment 35480.0 -6060.0 -0.35 39040.0 -1270.0 -0.1 -0.3163 -0.8688 3085961 TimTec1_004684 CCN(N)c1nc(Cl)cc(C)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E21 compound treatment 37000.0 -4540.0 -0.26 38240.0 -2070.0 -0.16 -0.2969 -0.9694 1723779 TimTec1_004685 COC(C(=O)Nc1ccc(Cl)cn1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E22 compound treatment 45400.0 3860.0 0.22 43240.0 2930.0 0.22 0.3149 1.0 1263589 TimTec1_004686 NCC1(CC2CC3C1)CC(CN)(C2)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E23 mock treatment 44680.0 3140.0 0.18 38880.0 -1430.0 -0.11 0.052 0.2457 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 E24 mock treatment 39040.0 -2500.0 -0.14 41760.0 1450.0 0.11 -0.0249 -0.1371 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F01 compound treatment 42960.0 1420.0 0.08 41160.0 849.0 0.06 0.1036 0.9926 1717073 TimTec1_004687 COc1ccc(CC2C(=O)NC(=O)N(C2=O)c3cccc(Cl)c3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F02 compound treatment 32040.0 -9500.0 -0.55 31960.0 -8350.0 -0.63 -0.8362 -0.9976 3085964 TimTec1_004688 S=C(NC(c1ccccc1)c2ccccc2)Nc3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F03 compound treatment 38480.0 -3060.0 -0.18 36680.0 -3630.0 -0.27 -0.3198 -0.9775 1738878 TimTec1_004689 CC(C)(C)c1nnc(Nc2ccc3OCOc3c2)n(N)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F04 compound treatment 40800.0 -741.0 -0.04 40560.0 249.0 0.02 -0.017 -0.3633 3085966 TimTec1_004690 OCc1ccccc1NC(=S)Nc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F05 compound treatment 28680.0 -12900.0 -0.75 28880.0 -11400.0 -0.87 -1.1387 -0.9972 3211421 TimTec1_004691 FC(F)(F)c1cccc(c1)N2C(Nc3ccccc3C2=O)c4ccc5cccnc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F06 compound treatment 33440.0 -8100.0 -0.47 30920.0 -9390.0 -0.71 -0.8345 -0.9797 1429088 TimTec1_004692 CC(C)CCOc1ccc(cc1)C2(C)NC(=O)N(CN3CCOCC3)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F07 compound treatment 35800.0 -5740.0 -0.33 32600.0 -7710.0 -0.58 -0.6479 -0.9645 3085968 TimTec1_004693 CCC(=O)Oc1ccc(cc1OC)C2CC(=O)c3c(N2)ccc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F08 compound treatment 38360.0 -3180.0 -0.18 37920.0 -2390.0 -0.18 -0.2583 -1.0 3085970 TimTec1_004694 OC(=O)c1cc(on1)c2ccc(O)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F09 compound treatment 26480.0 -15100.0 -0.87 28080.0 -12200.0 -0.93 -1.2717 -0.9996 3211422 TimTec1_004695 COc1ccc(cc1)C(=O)c2[nH]c(cc2c3ccccc3)c4ccc(OC)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F10 compound treatment 27240.0 -14300.0 -0.83 32200.0 -8110.0 -0.61 -1.02 -0.9891 1353733 TimTec1_004696 CCOC(=O)C1=C(CN(C1)C(=O)c2ccccc2)NN(C)c3ccc(OC)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F11 compound treatment 32280.0 -9260.0 -0.54 41320.0 1010.0 0.08 -0.3254 -0.6004 3085972 TimTec1_004697 Oc1[nH]nc2nc(cc(c12)C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F12 compound treatment 22400.0 -19100.0 -1.11 28800.0 -11500.0 -0.87 -1.4003 -0.9929 3211423 TimTec1_004698 CN(C1=C(C)CN(C2CCCCC2)C1=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F13 compound treatment 37880.0 -3660.0 -0.21 35960.0 -4350.0 -0.33 -0.3829 -0.9774 3211424 TimTec1_004699 Cc1nn(C(=O)COc2ccc(Cl)cc2Cl)c(N)c1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F14 compound treatment 29560.0 -12000.0 -0.69 34440.0 -5870.0 -0.44 -0.8051 -0.9768 3086016 TimTec1_004700 COc1ccc(cc1)N(C(C)C2C(C)(C)C2(C)C)C(=O)Nc3ccccc3N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F15 compound treatment 29440.0 -12100.0 -0.7 31880.0 -8430.0 -0.64 -0.947 -0.9989 3211510 TimTec1_004701 OC1(N(C2CC2)C(=O)c3ccccc31)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F16 compound treatment 36280.0 -5260.0 -0.3 32760.0 -7550.0 -0.57 -0.6197 -0.9567 1249129 TimTec1_004702 CCC1(COCc2ccccc2)CCC(O1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F17 compound treatment 20240.0 -21300.0 -1.23 23440.0 -16900.0 -1.28 -1.7757 -0.9999 3211511 TimTec1_004703 CCN(Cc1ccccc1)C(=O)c2sc3nc(C)cc(C)c3c2N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F18 compound treatment 25280.0 -16300.0 -0.94 25200.0 -15100.0 -1.14 -1.475 -0.9954 3086019 TimTec1_004704 COc1ccc2/C(=N/N)/CCCc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F19 compound treatment 24920.0 -16600.0 -0.96 28400.0 -11900.0 -0.9 -1.3185 -0.9995 3211512 TimTec1_004705 Nc1nnc(s1)c2ccc(Cn3c(nc4ccccc34)c5cncs5)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F20 compound treatment 27840.0 -13700.0 -0.79 24760.0 -15600.0 -1.18 -1.3937 -0.9816 3211513 TimTec1_004706 CS(=O)(=O)c1nc(Oc2cccc(c2)C(F)(F)F)cc(Oc3cccc(c3)C(F)(F)F)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F21 compound treatment 30760.0 -10800.0 -0.62 30600.0 -9710.0 -0.74 -0.9615 -0.9967 1223782 TimTec1_004707 OCC1CCCCN1C(=S)NCCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F22 compound treatment 42320.0 779.0 0.05 42480.0 2170.0 0.16 0.148 0.8692 3211514 TimTec1_004708 COc1ccc2C(=O)/C(=N\O)/CCCc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F23 mock treatment 42960.0 1420.0 0.08 42480.0 2170.0 0.16 0.1742 0.9488 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 F24 mock treatment 44800.0 3260.0 0.19 39360.0 -951.0 -0.07 0.0826 0.4088 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G01 compound treatment 39240.0 -2300.0 -0.13 40280.0 -31.0 0.0 -0.0959 -0.7194 1356880 TimTec1_004709 OC(=O)c1cc(nc2ccc(Br)cc12)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G02 compound treatment 26480.0 -15100.0 -0.87 30200.0 -10100.0 -0.77 -1.1582 -0.9979 3211515 TimTec1_004710 Brc1ccc(cc1)C2=CC(=O)OC(O2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G03 compound treatment 30640.0 -10900.0 -0.63 28600.0 -11700.0 -0.89 -1.0734 -0.9862 2106889 TimTec1_004711 Nc1nc(Cl)cc(Oc2ccc(Cl)cc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G04 compound treatment 37480.0 -4060.0 -0.24 39640.0 -671.0 -0.05 -0.2023 -0.8404 1151915 TimTec1_004712 CN1C(=O)C(Cc2c(C)[nH]c3ccccc23)C(=O)N(C)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G05 compound treatment 5840.0 -35700.0 -2.07 7360.0 -33000.0 -2.49 -3.2263 -0.9957 1509629 TimTec1_004713 Cn1c(SCC(=O)c2ccc3CCCCc3c2)nc4ccccc4c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G06 compound treatment 14400.0 -27100.0 -1.57 20320.0 -20000.0 -1.51 -2.1819 -0.9998 1368472 TimTec1_004714 Cc1nonc1NC(=O)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G07 compound treatment 20120.0 -21400.0 -1.24 21760.0 -18600.0 -1.4 -1.8705 -0.9981 1733999 TimTec1_004715 S=C1CCN(Cc2ccccc2)c3ccccc3N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G08 compound treatment 36520.0 -5020.0 -0.29 35360.0 -4950.0 -0.37 -0.4707 -0.9922 1463893 TimTec1_004716 CN1CCN(CC1)C(=O)c2c(C)oc3cc4c(C(=O)N5CCN(C)CC5)c(C)oc4cc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G09 compound treatment 28800.0 -12700.0 -0.74 31600.0 -8710.0 -0.66 -0.9882 -0.9984 3086027 TimTec1_004717 CCOc1ccc2nc(NC(NC(=O)CC)(C(F)(F)F)C(F)(F)F)sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G10 compound treatment 30600.0 -10900.0 -0.63 34920.0 -5390.0 -0.41 -0.7368 -0.9773 3211516 TimTec1_004718 Fc1ccc(cc1)c2n[nH]cc2C=C3C(=O)c4ccccc4C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G11 compound treatment 37040.0 -4500.0 -0.26 38360.0 -1950.0 -0.15 -0.2888 -0.9637 1735827 TimTec1_004719 CCN(CC)C(=S)Nc1ccc2oc(nc2c1)N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G12 compound treatment 30760.0 -10800.0 -0.62 31560.0 -8750.0 -0.66 -0.9101 -0.9996 3211517 TimTec1_004720 CC1(NN(C(=S)N1)c2ccccc2)C3(C)COCOC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G13 compound treatment 33480.0 -8060.0 -0.47 36280.0 -4030.0 -0.31 -0.546 -0.9787 3086031 TimTec1_004721 CCOc1ccccc1C(=O)n2cc(Cl)cn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G14 compound treatment 31520.0 -10000.0 -0.58 28320.0 -12000.0 -0.91 -1.0524 -0.9767 1425223 TimTec1_004722 COc1ccccc1N2C(=O)c3ccc(cc3C2=O)C(=O)Nc4cc(C)on4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G15 compound treatment 15280.0 -26300.0 -1.52 21080.0 -19200.0 -1.46 -2.1052 -0.9998 1383059 TimTec1_004723 CC1CCN(CC1)c2nc3nonc3nc2Nc4ccc5OCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G16 compound treatment 28320.0 -13200.0 -0.77 28680.0 -11600.0 -0.88 -1.1642 -0.9976 1606397 TimTec1_004724 O=S(=O)(NCC1(CC2CC3CC(C2)C1)C3)c4cccc5nsnc45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G17 compound treatment 37040.0 -4500.0 -0.26 32880.0 -7430.0 -0.56 -0.5821 -0.9389 3211518 TimTec1_004725 COc1ccc(CCN2C(CC(=O)N)C(=O)N(C2=S)c3cccc(c3)C(F)(F)F)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G18 compound treatment 29000.0 -12500.0 -0.73 28120.0 -12200.0 -0.92 -1.1663 -0.993 3086077 TimTec1_004726 Clc1cccc(c1)C2CC(=O)C(=CNC3CCCC3)C(=O)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G19 compound treatment 15080.0 -26500.0 -1.53 20520.0 -19800.0 -1.5 -2.1434 -0.9999 1327319 TimTec1_004727 COc1ccc(cc1OC)C2OC(COc3ccccc3)CN(O2)C(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G20 compound treatment 36840.0 -4700.0 -0.27 35080.0 -5230.0 -0.4 -0.4726 -0.9833 1653659 TimTec1_004728 Clc1ccc(cc1)c2csc3c4ncnc4ncn23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G21 compound treatment 38200.0 -3340.0 -0.19 37920.0 -2390.0 -0.18 -0.2649 -0.9994 3211519 TimTec1_004729 Cn1c(/C=C/C(=O)O)nc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G22 compound treatment 33120.0 -8420.0 -0.49 33560.0 -6750.0 -0.51 -0.7063 -0.9997 3211520 TimTec1_004730 COCc1cc(C)nc2sc3c(=O)n(nnc3c12)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G23 mock treatment 42040.0 499.0 0.03 41920.0 1610.0 0.12 0.1066 0.8512 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 G24 mock treatment 41760.0 219.0 0.01 37840.0 -2470.0 -0.19 -0.1233 -0.6577 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H01 compound treatment 35000.0 -6540.0 -0.38 40360.0 49.0 0.0 -0.2654 -0.7001 1710338 TimTec1_004731 Cn1c(CS(=O)(=O)c2ccccc2)c(C#N)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H02 compound treatment 33480.0 -8060.0 -0.47 37360.0 -2950.0 -0.22 -0.4882 -0.943 3211521 TimTec1_004732 Clc1ccc(CS(=O)(=O)c2nc3cccnc3[nH]2)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H03 compound treatment 8040.0 -33500.0 -1.94 10480.0 -29800.0 -2.26 -2.9692 -0.9972 3086082 TimTec1_004733 Cc1[nH]c2ccccc2c1CCN3C(=O)c4ccccc4C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H04 compound treatment 35600.0 -5940.0 -0.34 38520.0 -1790.0 -0.14 -0.3393 -0.917 3211522 TimTec1_004734 O=C(NC(=O)c1cccs1)OC[C@@H]2CCCN3CCCCC23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H05 compound treatment 30720.0 -10800.0 -0.63 34320.0 -5990.0 -0.45 -0.764 -0.9874 3086084 TimTec1_004735 OC(=O)CCc1ccc(c2ccccc2)n1c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H06 compound treatment 29760.0 -11800.0 -0.68 30520.0 -9790.0 -0.74 -1.0067 -0.9992 3211523 TimTec1_004736 OC1(CC(=NN1C(=O)c2cccnc2)C(F)(F)F)c3ccncc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H07 compound treatment 24400.0 -17100.0 -0.99 23360.0 -17000.0 -1.28 -1.6095 -0.992 3211524 TimTec1_004737 Fc1cccc(c1)C(=O)NC(=O)Nc2nc(cc(n2)C(F)(F)F)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H08 compound treatment 3080.0 -38500.0 -2.23 4640.0 -35700.0 -2.7 -3.4849 -0.9955 3086087 TimTec1_004738 Fc1ccccc1CCNc2c3CCCCc3nc4ncnn24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H09 compound treatment 30440.0 -11100.0 -0.64 31120.0 -9190.0 -0.7 -0.9467 -0.9992 3086089 TimTec1_004739 Cc1ccoc1C(=O)NCCN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H10 compound treatment 30920.0 -10600.0 -0.62 37000.0 -3310.0 -0.25 -0.6123 -0.9216 1653767 TimTec1_004740 CCOC(=O)C1=C(NC(C)C)C(=O)N(C1)N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H11 compound treatment 26400.0 -15100.0 -0.88 30240.0 -10100.0 -0.76 -1.1593 -0.9976 3211525 TimTec1_004741 CC1Cc2nn(c(c2C(=O)C1C)c3cccnc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H12 compound treatment 28360.0 -13200.0 -0.76 25240.0 -15100.0 -1.14 -1.3467 -0.981 1563400 TimTec1_004742 CN1CC(=C(NC2CCCCC2)C1=O)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H13 compound treatment 33240.0 -8300.0 -0.48 27360.0 -13000.0 -0.98 -1.0333 -0.9463 3211526 TimTec1_004743 O=C1N(Cc2cccnc2)C(NCc3cccnc3)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H14 compound treatment 33800.0 -7740.0 -0.45 35480.0 -4830.0 -0.37 -0.5757 -0.9949 3086093 TimTec1_004744 Cc1cc(C)[n+]2c(csc2n1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H15 compound treatment 32400.0 -9140.0 -0.53 33800.0 -6510.0 -0.49 -0.723 -0.9994 1868951 TimTec1_004745 CCOC(=O)c1c(C)cc(C)[nH]c1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H16 compound treatment 28800.0 -12700.0 -0.74 26040.0 -14300.0 -1.08 -1.2858 -0.9828 1285461 TimTec1_004746 COc1cc(C(=O)CN2C(=O)c3ccccc3C2=O)c(OC)cc1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H17 compound treatment 35720.0 -5820.0 -0.34 37320.0 -2990.0 -0.23 -0.3986 -0.9812 3086156 TimTec1_004747 CCOc1ccc(CCNC(=O)Cc2nnc[nH]2)cc1OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H18 compound treatment 36800.0 -4740.0 -0.27 33880.0 -6430.0 -0.49 -0.5385 -0.9633 1091806 TimTec1_004748 CCC1C[N+]2(C)CCc3cc(OC)c(OC)cc3C2CC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H19 compound treatment 35480.0 -6060.0 -0.35 38720.0 -1590.0 -0.12 -0.3335 -0.8982 3086159 TimTec1_004749 Cc1cc(C)n2nc(nc2n1)S(=O)(=O)NC3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H20 compound treatment 36880.0 -4660.0 -0.27 36680.0 -3630.0 -0.27 -0.3853 -1.0 3211527 TimTec1_004750 CS(=O)(=O)c1ccc(C(=O)O)c(O)c1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H21 compound treatment 36960.0 -4580.0 -0.27 35760.0 -4550.0 -0.34 -0.4313 -0.9917 3211528 TimTec1_004751 CC(C)(C)NC(=O)Cn1nnc(n1)c2ccc(cc2)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H22 compound treatment 40160.0 -1380.0 -0.08 39280.0 -1030.0 -0.08 -0.1118 -0.9999 1019007 TimTec1_004752 COc1ncnc2[nH]cnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H23 mock treatment 38920.0 -2620.0 -0.15 42160.0 1850.0 0.14 -0.0084 -0.0408 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 H24 mock treatment 37200.0 -4340.0 -0.25 38440.0 -1870.0 -0.14 -0.278 -0.9631 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I01 compound treatment 40800.0 -741.0 -0.04 42360.0 2050.0 0.16 0.0793 0.4928 1573225 TimTec1_004753 O=C(N1CCOCC1)c2ccccc2C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I02 compound treatment 25360.0 -16200.0 -0.94 29520.0 -10800.0 -0.82 -1.2405 -0.9976 1382795 TimTec1_004754 O=C(CSc1ccccn1)c2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I03 compound treatment 36000.0 -5540.0 -0.32 39360.0 -951.0 -0.07 -0.2779 -0.8447 1128047 TimTec1_004755 O=C(Oc1cccc2cccnc12)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I04 compound treatment 33880.0 -7660.0 -0.44 37600.0 -2710.0 -0.21 -0.459 -0.9386 1498538 TimTec1_004756 CC(NC(=O)c1nc[nH]n1)c2ccc(cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I05 compound treatment 32520.0 -9020.0 -0.52 33960.0 -6350.0 -0.48 -0.7095 -0.9991 1694793 TimTec1_004757 NC(=O)N1CCC(=O)Nc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I06 compound treatment 32120.0 -9420.0 -0.55 29000.0 -11300.0 -0.86 -0.9914 -0.9764 1660022 TimTec1_004758 CC12CCCCC2N(CC(=O)N)c3ccccc31 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I07 compound treatment 1360.0 -40200.0 -2.33 1280.0 -39000.0 -2.95 -3.7352 -0.993 1335680 TimTec1_004759 Cc1nc2ccccn2c1c3csc(Nc4ccc(C)cc4C)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I08 compound treatment 20640.0 -20900.0 -1.21 27440.0 -12900.0 -0.97 -1.5452 -0.9942 1266099 TimTec1_004760 Clc1ccc2oc(=O)n(C(=O)Oc3ccccc3)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I09 compound treatment 34400.0 -7140.0 -0.41 43080.0 2770.0 0.21 -0.1444 -0.3112 3211606 TimTec1_004761 OC(=O)C(Cc1ccccc1)P(=O)(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I10 compound treatment 31200.0 -10300.0 -0.6 32360.0 -7950.0 -0.6 -0.8492 -1.0 3086166 TimTec1_004762 COc1ccc(c2nnc3ccc(Cl)nn23)c(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I11 compound treatment 16720.0 -24800.0 -1.44 17600.0 -22700.0 -1.72 -2.2325 -0.9961 1268857 TimTec1_004763 COc1ccc(c2csc(n2)C3COc4ccccc4O3)c(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I12 compound treatment 30560.0 -11000.0 -0.64 29840.0 -10500.0 -0.79 -1.0103 -0.9941 1370075 TimTec1_004764 CN(C(=O)Cn1nnnc1N)C2(CCCCC2)C(=O)Nc3ccccc3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I13 compound treatment 30880.0 -10700.0 -0.62 27520.0 -12800.0 -0.97 -1.1214 -0.9764 1698831 TimTec1_004765 O=c1nc(Nc2ccccc2)[nH]c(=O)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I14 compound treatment 28520.0 -13000.0 -0.75 30240.0 -10100.0 -0.76 -1.0725 -1.0 3211607 TimTec1_004766 Cc1ccc(/C(=C/C2=NCCNC(C2)c3ccccc3)/O)c(O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I15 compound treatment 34920.0 -6620.0 -0.38 35720.0 -4590.0 -0.35 -0.517 -0.9988 1314790 TimTec1_004767 COC(C(=O)NCc1cccnc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I16 compound treatment 37840.0 -3700.0 -0.21 31640.0 -8670.0 -0.66 -0.6157 -0.8917 3211608 TimTec1_004768 CCCC/1=NN(C(=O)\C1=C/N)c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I17 compound treatment 29400.0 -12100.0 -0.7 27000.0 -13300.0 -1.01 -1.2099 -0.9846 1621835 TimTec1_004769 CCN(CC)c1ccc2c(=O)[nH][nH]c(=O)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I18 compound treatment 3920.0 -37600.0 -2.18 4240.0 -36100.0 -2.73 -3.4719 -0.9938 1274514 TimTec1_004770 Fc1ccc(cc1)c2cn3nc4CCCCc4nc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I19 compound treatment 32640.0 -8900.0 -0.52 36120.0 -4190.0 -0.32 -0.589 -0.9728 1017274 TimTec1_004771 CCOC(=O)c1cnc2ccc(OC)cc2c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I20 compound treatment 32440.0 -9100.0 -0.53 40160.0 -151.0 -0.01 -0.3809 -0.7223 1179846 TimTec1_004772 O=C(c1ccccc1)c2ccc(cc2)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I21 compound treatment 36440.0 -5100.0 -0.3 37960.0 -2350.0 -0.18 -0.3348 -0.9705 1674029 TimTec1_004773 CCCCC(N1C(=O)C2C3CC(C=C3)C2C1=O)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I22 compound treatment 9600.0 -31900.0 -1.85 9200.0 -31100.0 -2.35 -2.9738 -0.9929 1703643 TimTec1_004774 COCc1cc(C)nc2sc3C(=O)NC(Nc3c12)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I23 mock treatment 34240.0 -7300.0 -0.42 39680.0 -631.0 -0.05 -0.3329 -0.782 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 I24 mock treatment 41040.0 -501.0 -0.03 40600.0 289.0 0.02 -0.0051 -0.1393 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J01 compound treatment 7640.0 -33900.0 -1.96 12200.0 -28100.0 -2.13 -2.8935 -0.9992 1596975 TimTec1_004775 COc1ccc(cc1)C(=O)n2c(=S)nc3cc(C)ccn23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J02 compound treatment 28080.0 -13500.0 -0.78 22360.0 -18000.0 -1.36 -1.5123 -0.9653 3211609 TimTec1_004776 Cc1ccc(cc1)C(=O)OC2CC(OC2CO)n3ccc(NC(=O)c4ccccc4)nc3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J03 compound treatment 38840.0 -2700.0 -0.16 39800.0 -511.0 -0.04 -0.138 -0.8561 1526337 TimTec1_004777 COc1ccc(cc1)C2=C(CC(=O)O)C(=O)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J04 compound treatment 35040.0 -6500.0 -0.38 36600.0 -3710.0 -0.28 -0.465 -0.9896 3211610 TimTec1_004778 Cc1ccc(cc1)C(=O)NC(=O)OC[C@@H]2CCCN3CCCCC23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J05 compound treatment 24480.0 -17100.0 -0.99 27480.0 -12800.0 -0.97 -1.3857 -1.0 1520302 TimTec1_004779 C(Cn1c(COc2ccccc2)nc3ccccc13)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J06 compound treatment 26760.0 -14800.0 -0.86 27360.0 -13000.0 -0.98 -1.2987 -0.9977 1554201 TimTec1_004780 Cc1ccc(cc1)N(C(=O)c2ccccn2)C3(CCCCC3)C(=O)Nc4c(C)cccc4C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J07 compound treatment 34320.0 -7220.0 -0.42 35160.0 -5150.0 -0.39 -0.5715 -0.9994 3211611 TimTec1_004781 Cc1ccc(cc1C)n2nc(C(=O)O)c(/C=C/c3ccc(Cl)cc3Cl)c(C#N)c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J08 compound treatment 5600.0 -35900.0 -2.08 8280.0 -32000.0 -2.42 -3.1869 -0.9971 3086243 TimTec1_004782 Clc1ccc(NCc2ccccc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J09 compound treatment 27120.0 -14400.0 -0.84 27880.0 -12400.0 -0.94 -1.2562 -0.9982 3211612 TimTec1_004783 C(c1cn(Cc2ccccc2)nn1)n3nnc(n3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J10 compound treatment 31640.0 -9900.0 -0.57 31160.0 -9150.0 -0.69 -0.8954 -0.9956 1008095 TimTec1_004784 NC(=S)Nc1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J11 compound treatment 32040.0 -9500.0 -0.55 29320.0 -11000.0 -0.83 -0.9775 -0.9799 3211613 TimTec1_004785 OC(=O)CCN1CCn2c1nc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J12 compound treatment 5120.0 -36400.0 -2.11 5680.0 -34600.0 -2.62 -3.3457 -0.9942 1404920 TimTec1_004786 CCOC(=O)C1=C(NC2CCCCC2)C(=O)N(C1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J13 compound treatment 36600.0 -4940.0 -0.29 33480.0 -6830.0 -0.52 -0.5681 -0.9611 3211614 TimTec1_004787 CCOc1ccc(CC(=O)C2C(=O)CC(C)(C)CC2=O)cc1OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J14 compound treatment 36640.0 -4900.0 -0.28 33480.0 -6830.0 -0.52 -0.5664 -0.9602 1418487 TimTec1_004788 CCOC(=O)c1nccnc1N(C(=O)c2ccc(C)cc2)C(=O)c3ccc(C)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J15 compound treatment 5560.0 -36000.0 -2.08 6640.0 -33700.0 -2.55 -3.2763 -0.995 3086247 TimTec1_004789 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NC4CCCC4)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J16 compound treatment 27480.0 -14100.0 -0.81 24960.0 -15400.0 -1.16 -1.3977 -0.9849 3211615 TimTec1_004790 CSC(=S)NCc1cccs1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J17 compound treatment 9640.0 -31900.0 -1.85 16840.0 -23500.0 -1.78 -2.5632 -0.9998 3211616 TimTec1_004791 CCC1(CN2CC3(CC)CN(C1)C2c4c(C)[nH]c5ccccc45)C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J18 compound treatment 33960.0 -7580.0 -0.44 32120.0 -8190.0 -0.62 -0.749 -0.9857 1118951 TimTec1_004792 CC1=CC(=O)CN(C1)S(=O)(=O)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J19 compound treatment 32360.0 -9180.0 -0.53 34840.0 -5470.0 -0.41 -0.669 -0.9923 3086250 TimTec1_004793 CS(=O)(=O)NCc1ccc(cc1)C(=O)NCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J20 compound treatment 26800.0 -14700.0 -0.85 35480.0 -4830.0 -0.37 -0.8625 -0.9283 3211617 TimTec1_004794 Fc1cccc2ncnc(OCc3ccccc3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J21 compound treatment 31800.0 -9740.0 -0.56 30560.0 -9750.0 -0.74 -0.921 -0.9912 3211618 TimTec1_004795 COc1ccccc1NC(=O)C(F)(F)C(=O)Nc2ccccc2OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J22 compound treatment 24680.0 -16900.0 -0.98 28320.0 -12000.0 -0.91 -1.3326 -0.9993 1295066 TimTec1_004796 Cc1ccc(cc1)S(=O)(=O)N2CC(=O)CCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J23 mock treatment 37080.0 -4460.0 -0.26 41720.0 1410.0 0.11 -0.1074 -0.3839 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 J24 mock treatment 33680.0 -7860.0 -0.46 40000.0 -311.0 -0.02 -0.3387 -0.7427 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K01 compound treatment 3400.0 -38100.0 -2.21 4840.0 -35500.0 -2.68 -3.4611 -0.9953 3211619 TimTec1_004797 Cc1ccc(NC(=O)c2ccccc2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K02 compound treatment 20840.0 -20700.0 -1.2 19480.0 -20800.0 -1.58 -1.963 -0.9909 1736764 TimTec1_004798 CC(C)Cc1nc(C#N)c(N)c(c1C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K03 compound treatment 28160.0 -13400.0 -0.78 30480.0 -9830.0 -0.74 -1.0744 -0.9998 1338385 TimTec1_004799 CN(C)N=Nc1ccc(cc1)S(=O)(=O)N(C(=O)C)C(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K04 compound treatment 24240.0 -17300.0 -1.0 26480.0 -13800.0 -1.05 -1.4491 -0.9998 1523329 TimTec1_004800 COc1cc(ccc1O)C2N(Cc3ccccc3)CCCN2Cc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K05 compound treatment 24000.0 -17500.0 -1.02 23920.0 -16400.0 -1.24 -1.5959 -0.9951 1577188 TimTec1_004801 CC1CC(=O)Nc2ccccc2N1C=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K06 compound treatment 27080.0 -14500.0 -0.84 27960.0 -12400.0 -0.93 -1.2535 -0.9985 1555913 TimTec1_004802 Cc1ccc(NC(=O)C2(CCCCC2)NC(=O)c3ccc(cc3)n4cnnn4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K07 compound treatment 1800.0 -39700.0 -2.3 2080.0 -38200.0 -2.89 -3.6744 -0.9936 3211620 TimTec1_004803 Cc1nc2ccccn2c1c3csc(Nc4ccc(Br)cc4Br)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K08 compound treatment 28840.0 -12700.0 -0.74 26840.0 -13500.0 -1.02 -1.2414 -0.9872 3086325 TimTec1_004804 OCC1(CCCCC1)C2=NOC(O)(C2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K09 compound treatment 26040.0 -15500.0 -0.9 27920.0 -12400.0 -0.94 -1.2983 -0.9998 1021311 TimTec1_004805 C[N+]1(CC[N+]2(C)CCCCC2)CCCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K10 compound treatment 22560.0 -19000.0 -1.1 22440.0 -17900.0 -1.35 -1.7342 -0.9947 1399338 TimTec1_004806 OC(C1CN2CCC1CC2)(c3cccc(Cl)c3)c4cccc(Cl)c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K11 compound treatment 7800.0 -33700.0 -1.95 10520.0 -29800.0 -2.26 -2.9768 -0.9975 3086328 TimTec1_004807 Cc1ccc(CC2SC(=NC2=O)N3CCN(CC3)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K12 compound treatment 20560.0 -21000.0 -1.22 23200.0 -17100.0 -1.3 -1.7754 -0.9995 1611430 TimTec1_004808 CC1CCc2nc3ccc4ccccc4c3c(c5ccc(O)c(O)c5)c2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K13 compound treatment 25600.0 -15900.0 -0.92 27880.0 -12400.0 -0.94 -1.3184 -1.0 1442519 TimTec1_004809 CC(=O)OC1CCC(C(OC(=O)C)C1[N+](C)(C)C)[N+](C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K14 compound treatment 28480.0 -13100.0 -0.76 25520.0 -14800.0 -1.12 -1.3268 -0.9818 1912712 TimTec1_004810 CC1=CC(C)(C)C(C(C1)C(=O)O)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K15 compound treatment 7480.0 -34100.0 -1.97 7720.0 -32600.0 -2.47 -3.1398 -0.9939 1608847 TimTec1_004811 Cc1ccc(cc1)S(=O)(=O)N2N=NC3C4CC(C5CC=CC54)C32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K16 compound treatment 17040.0 -24500.0 -1.42 18440.0 -21900.0 -1.66 -2.1744 -0.9971 3211621 TimTec1_004812 FC(F)(F)c1cccc(NC(=O)NC2(CC2)c3ccccc3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K17 compound treatment 27200.0 -14300.0 -0.83 26320.0 -14000.0 -1.06 -1.3364 -0.9928 3086332 TimTec1_004813 COc1nsc(Br)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K18 compound treatment 30440.0 -11100.0 -0.64 29120.0 -11200.0 -0.85 -1.0538 -0.9908 1299455 TimTec1_004814 CC1Nc2ccccc2C(=O)N1NC(=O)c3ccc(Br)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K19 compound treatment 17320.0 -24200.0 -1.4 20680.0 -19600.0 -1.49 -2.043 -0.9996 1278796 TimTec1_004815 O=C(Cc1ccccc1)N2CCC(=N2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K20 compound treatment 32200.0 -9340.0 -0.54 29080.0 -11200.0 -0.85 -0.9838 -0.9762 1293299 TimTec1_004816 COc1ccc(CCn2c(N)cc(=O)[nH]c2=O)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K21 compound treatment 29000.0 -12500.0 -0.73 26760.0 -13600.0 -1.03 -1.2391 -0.9857 1371336 TimTec1_004817 CCCCC(=O)Nc1c(nc2ccccn12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K22 compound treatment 32480.0 -9060.0 -0.52 30960.0 -9350.0 -0.71 -0.8717 -0.9892 3211728 TimTec1_004818 Brc1cnn(c2ccccc2)c(=O)c1NCCCN3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K23 mock treatment 37320.0 -4220.0 -0.24 32840.0 -7470.0 -0.57 -0.5728 -0.9297 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 K24 mock treatment 33640.0 -7900.0 -0.46 32040.0 -8270.0 -0.63 -0.7664 -0.9882 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L01 compound treatment 39520.0 -2020.0 -0.12 38400.0 -1910.0 -0.14 -0.1851 -0.9945 1208379 TimTec1_004819 O=C(c1ccco1)n2c(=S)nc3ccccn23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L02 compound treatment 20680.0 -20900.0 -1.21 22080.0 -18200.0 -1.38 -1.8304 -0.9978 3211729 TimTec1_004820 O=C1CC(CN1)c2ccc(cc2)S(=O)(=O)NCc3ccncc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L03 compound treatment 38360.0 -3180.0 -0.18 38600.0 -1710.0 -0.13 -0.2219 -0.9851 3211730 TimTec1_004821 CCOC(=O)c1nc(N)c(=O)n(n1)c2ccc(cc2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L04 compound treatment 33720.0 -7820.0 -0.45 37400.0 -2910.0 -0.22 -0.4762 -0.9451 3086338 TimTec1_004822 CN1C2=C(C(NC1=O)c3ccc(O)cc3)C(=O)N(CCO)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L05 compound treatment 16480.0 -25100.0 -1.45 16520.0 -23800.0 -1.8 -2.3001 -0.9943 3211731 TimTec1_004823 CC1(C)Cc2ccccc2C(=N1)c3sc4nc5CCCCCc5cc4c3N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L06 compound treatment 12800.0 -28700.0 -1.67 13480.0 -26800.0 -2.03 -2.6136 -0.9951 1225977 TimTec1_004824 Cc1cc(NC(=O)Cc2ccccc2)ccc1c3cc4ccccc4oc3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L07 compound treatment 2040.0 -39500.0 -2.29 1120.0 -39200.0 -2.97 -3.7159 -0.9918 3086341 TimTec1_004825 CC(C)n1c(COc2ccc(Cl)cc2)nc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L08 compound treatment 26640.0 -14900.0 -0.86 22400.0 -17900.0 -1.36 -1.5691 -0.9763 1395920 TimTec1_004826 COC(=O)C1=C(CN(C1)c2ccccc2)NN(C)c3ccc(OC)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L09 compound treatment 26840.0 -14700.0 -0.85 25960.0 -14400.0 -1.09 -1.3704 -0.9928 3086343 TimTec1_004827 Cc1ccsc1CNn2cnnc2SCc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L10 compound treatment 21480.0 -20100.0 -1.16 23520.0 -16800.0 -1.27 -1.7206 -0.999 3086416 TimTec1_004828 CN(NC(=S)Nc1ccccc1)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L11 compound treatment 16600.0 -24900.0 -1.45 17880.0 -22400.0 -1.7 -2.2224 -0.9968 3211732 TimTec1_004829 Cc1nn(C(=O)c2c[nH]c3ccccc23)c(N)c1c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L12 compound treatment 27400.0 -14100.0 -0.82 30440.0 -9870.0 -0.75 -1.1077 -0.9989 3086420 TimTec1_004830 O/N=C/c1nc2ccccc2[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L13 compound treatment 31080.0 -10500.0 -0.61 26520.0 -13800.0 -1.04 -1.1667 -0.9666 3211733 TimTec1_004831 Nn1c(S)nnc1Cc2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L14 compound treatment 31320.0 -10200.0 -0.59 27440.0 -12900.0 -0.97 -1.1077 -0.9715 3086422 TimTec1_004832 OC/C=C/c1ccc(O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L15 compound treatment 29920.0 -11600.0 -0.67 30200.0 -10100.0 -0.77 -1.0173 -0.998 3211734 TimTec1_004833 COc1ccc(c2cc(n[nH]2)C(=O)N)c(F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L16 compound treatment 39920.0 -1620.0 -0.09 34360.0 -5950.0 -0.45 -0.3849 -0.8366 3086423 TimTec1_004834 CC(C)(C)c1ccc(cc1)S(=O)(=O)NC(=O)c2cccc(Oc3cccc(c3)C(F)(F)F)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L17 compound treatment 36840.0 -4700.0 -0.27 35600.0 -4710.0 -0.36 -0.4448 -0.9912 3211735 TimTec1_004835 OCC1OC(Nc2ccccn2)C(O)C(O)C1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L18 compound treatment 24480.0 -17100.0 -0.99 26040.0 -14300.0 -1.08 -1.4628 -0.999 1186126 TimTec1_004836 COc1ccc2c3CCc4c([nH]c5ccccc45)-c3ccc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L19 compound treatment 14720.0 -26800.0 -1.55 12920.0 -27400.0 -2.07 -2.5649 -0.9899 3086426 TimTec1_004837 Cc1cccc(C)c1OCCN2C(=O)c3ccccc3C2(O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L20 compound treatment 26240.0 -15300.0 -0.89 29160.0 -11200.0 -0.84 -1.2237 -0.9997 1122321 TimTec1_004838 CCC1Nc2ccccc2NC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L21 compound treatment 32600.0 -8940.0 -0.52 33960.0 -6350.0 -0.48 -0.7062 -0.9993 1235395 TimTec1_004839 S=C(Nc1cccnc1)N(CCc2ccccc2)Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L22 compound treatment 39000.0 -2540.0 -0.15 29600.0 -10700.0 -0.81 -0.6774 -0.8221 3086429 TimTec1_004840 O/N=C/C(=O)Nc1ccccc1I 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L23 mock treatment 41200.0 -341.0 -0.02 41800.0 1490.0 0.11 0.0657 0.5743 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 L24 mock treatment 37080.0 -4460.0 -0.26 35960.0 -4350.0 -0.33 -0.4157 -0.9928 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M01 compound treatment 35160.0 -6380.0 -0.37 39040.0 -1270.0 -0.1 -0.3295 -0.8624 1539018 TimTec1_004841 CC(C)(C)NCC(O)COc1c(Br)ccc2c1sc3nc4CCCCCn4c(=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M02 compound treatment 39960.0 -1580.0 -0.09 42240.0 1930.0 0.15 0.0385 0.2232 1251587 TimTec1_004842 CCCc1nc2c(sc3nc(COC)cc(C)c32)c4nc5ccccc5n14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M03 compound treatment 27280.0 -14300.0 -0.83 31880.0 -8430.0 -0.64 -1.0355 -0.9919 1774729 TimTec1_004843 O=C(OC1CS(=O)(=O)CC1OC(=O)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M04 compound treatment 28920.0 -12600.0 -0.73 33720.0 -6590.0 -0.5 -0.8698 -0.9826 3086431 TimTec1_004844 CCC(=O)Nc1nc2nc(COC)cc(O)n2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M05 compound treatment 34000.0 -7540.0 -0.44 31440.0 -8870.0 -0.67 -0.7838 -0.9783 3211736 TimTec1_004845 CC1CC(=O)N(C(=O)C)c2ccccc2N1C(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M06 compound treatment 29440.0 -12100.0 -0.7 26320.0 -14000.0 -1.06 -1.2446 -0.9799 1645856 TimTec1_004846 CCOC(=O)CNc1nc(Cl)nc(NCC=C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M07 compound treatment 29680.0 -11900.0 -0.69 34840.0 -5470.0 -0.41 -0.7788 -0.9706 1505508 TimTec1_004847 OC(=O)CCNS(=O)(=O)c1ccc2ccccc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M08 compound treatment 36960.0 -4580.0 -0.27 34000.0 -6310.0 -0.48 -0.5255 -0.9615 3211737 TimTec1_004848 OC(=O)Cn1cc(/C=C/2\C(=O)NN(C2=O)c3ccccc3)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M09 compound treatment 30280.0 -11300.0 -0.65 27800.0 -12500.0 -0.95 -1.131 -0.9835 3211738 TimTec1_004849 OC(C(O)c1nnc(S)n1c2ccccc2)c3nnc(S)n3c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M10 compound treatment 31760.0 -9780.0 -0.57 31400.0 -8910.0 -0.67 -0.8777 -0.9962 3086435 TimTec1_004850 OC(=O)c1ccc(CSc2nnc(Cc3ccccc3)n2c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M11 compound treatment 29840.0 -11700.0 -0.68 26520.0 -13800.0 -1.04 -1.2175 -0.9782 3211739 TimTec1_004851 CCOC(=O)CN1NC(CC)(NC1=S)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M12 compound treatment 1200.0 -40300.0 -2.34 1320.0 -39000.0 -2.95 -3.7397 -0.9933 3211740 TimTec1_004852 Cc1onc(c1C(=O)NCCOC2(CC3CC4CC(C3)C2)C4)c5ccccc5Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M13 compound treatment 24520.0 -17000.0 -0.99 23600.0 -16700.0 -1.26 -1.5918 -0.9924 1320456 TimTec1_004853 Oc1ncnc2nn(nc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M14 compound treatment 30960.0 -10600.0 -0.61 27240.0 -13100.0 -0.99 -1.1331 -0.9735 1262859 TimTec1_004854 C=CCN1C(=O)C(Cc2c[nH]c3ccccc23)NC1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M15 compound treatment 32400.0 -9140.0 -0.53 28880.0 -11400.0 -0.87 -0.9863 -0.9723 1260852 TimTec1_004855 COc1ccccc1N2CCSC2C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M16 compound treatment 36800.0 -4740.0 -0.27 30880.0 -9430.0 -0.71 -0.699 -0.9139 1602518 TimTec1_004856 COC(=O)c1cc(=O)c2c(SC)nc(nc2[nH]1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M17 compound treatment 26200.0 -15300.0 -0.89 24040.0 -16300.0 -1.23 -1.4994 -0.9872 1218046 TimTec1_004857 CC(C)(O)C#Cc1ccc(o1)C(=O)N2CCC(CC2)C(O)(c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M18 compound treatment 34240.0 -7300.0 -0.42 33320.0 -6990.0 -0.53 -0.6733 -0.9938 1375886 TimTec1_004858 CC(C)c1ccc(cc1)S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M19 compound treatment 33240.0 -8300.0 -0.48 34280.0 -6030.0 -0.46 -0.6629 -0.9997 1685209 TimTec1_004859 O=C1NC(=O)C(CCc2ccccn2)(CCc3ccccn3)C(=O)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M20 compound treatment 27360.0 -14200.0 -0.82 26280.0 -14000.0 -1.06 -1.332 -0.992 3211741 TimTec1_004860 Cc1nnc(c2ccccc2)c(=O)n1/N=C/c3ccc(O)c(O)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M21 compound treatment 16600.0 -24900.0 -1.45 15920.0 -24400.0 -1.85 -2.3273 -0.9927 1591983 TimTec1_004861 O=C(NC1CCCCC1)n2c(=O)oc3cc(ccc23)S(=O)(=O)N4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M22 compound treatment 38560.0 -2980.0 -0.17 37880.0 -2430.0 -0.18 -0.2523 -0.9995 3086509 TimTec1_004862 Cc1cc(C)n(n1)c2n[nH]c(=S)n2N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M23 mock treatment 40200.0 -1340.0 -0.08 37120.0 -3190.0 -0.24 -0.2257 -0.8897 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 M24 mock treatment 42160.0 619.0 0.04 38640.0 -1670.0 -0.13 -0.0641 -0.4875 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N01 compound treatment 35720.0 -5820.0 -0.34 40200.0 -111.0 -0.01 -0.2444 -0.7245 1431780 TimTec1_004863 Oc1nnc(c2ncc[nH]2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N02 compound treatment 35680.0 -5860.0 -0.34 39280.0 -1030.0 -0.08 -0.2953 -0.8475 3211742 TimTec1_004864 CCOc1ccc(cc1S(=O)(=O)NC2CC2)n3cnnn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N03 compound treatment 35640.0 -5900.0 -0.34 31040.0 -9270.0 -0.7 -0.738 -0.9454 3086512 TimTec1_004865 CCN1CN(Cc2ccccc2)CNC1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N04 compound treatment 23680.0 -17900.0 -1.03 25600.0 -14700.0 -1.11 -1.5191 -0.9993 3211743 TimTec1_004866 CC1(C2c3ccccc3OC(=O)C21C(=O)N4CCOCC4)C(=O)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N05 compound treatment 25080.0 -16500.0 -0.95 22800.0 -17500.0 -1.33 -1.6116 -0.987 3211744 TimTec1_004867 CCCCn1c(cc(=O)c2c(C)n(c3ccccc3)c(=S)nc12)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N06 compound treatment 6560.0 -35000.0 -2.03 7520.0 -32800.0 -2.48 -3.1882 -0.9949 3086514 TimTec1_004868 Cc1cccc(NCc2c(C#N)c3ccccc3n2C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N07 compound treatment 28160.0 -13400.0 -0.78 32160.0 -8150.0 -0.62 -0.9845 -0.9936 3211745 TimTec1_004869 CCOc1nc(OCC)nc(n1)n2cc(nn2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N08 compound treatment 22720.0 -18800.0 -1.09 24720.0 -15600.0 -1.18 -1.6056 -0.9992 1416515 TimTec1_004870 CCOC(=O)C1=C(NN(C)c2ccccc2)C(=O)N(C)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N09 compound treatment 9040.0 -32500.0 -1.88 8600.0 -31700.0 -2.4 -3.0288 -0.9928 3211746 TimTec1_004871 Nc1nc-2c(CCc3c2cnn3c4ccccc4)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N10 compound treatment 32240.0 -9300.0 -0.54 25800.0 -14500.0 -1.1 -1.1577 -0.9463 1675882 TimTec1_004872 CCOC(=O)C1=C(N)C(=O)N(CCCN2CCOCC2)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N11 compound treatment 17520.0 -24000.0 -1.39 13920.0 -26400.0 -2.0 -2.3967 -0.9844 3211837 TimTec1_004873 CCOc1nc(NC(=O)NC(=O)c2c(F)cccc2F)nc(n1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N12 compound treatment 27560.0 -14000.0 -0.81 29040.0 -11300.0 -0.85 -1.1761 -0.9997 3086517 TimTec1_004874 Cn1c(/C=N/O)nc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N13 compound treatment 27440.0 -14100.0 -0.82 24840.0 -15500.0 -1.17 -1.4058 -0.9845 3211838 TimTec1_004875 COC(=O)Nc1ccc2n(cnc2c1)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N14 compound treatment 22120.0 -19400.0 -1.13 18480.0 -21800.0 -1.65 -1.9641 -0.9825 1164968 TimTec1_004876 O=C(NCCc1ccccc1)C2c3ccccc3-c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N15 compound treatment 30280.0 -11300.0 -0.65 28360.0 -12000.0 -0.9 -1.101 -0.9871 3211839 TimTec1_004877 Cc1n[nH]c2nc3n(C)c(=O)n(C)c(=O)c3c(OC(=O)c4ccccc4)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N16 compound treatment 27760.0 -13800.0 -0.8 23120.0 -17200.0 -1.3 -1.4847 -0.9725 3086520 TimTec1_004878 CNC(=O)c1cccc(Oc2cccc(Cl)n2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N17 compound treatment 29160.0 -12400.0 -0.72 28960.0 -11400.0 -0.86 -1.1148 -0.996 1658721 TimTec1_004879 S=C(NCCN1CCOCC1)NC2CCCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N18 compound treatment 18920.0 -22600.0 -1.31 22320.0 -18000.0 -1.36 -1.8897 -0.9998 1394340 TimTec1_004880 Cc1ccc(cc1)S(=O)(=O)N2CC(=O)c3ccccc3-c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N19 compound treatment 31680.0 -9860.0 -0.57 28640.0 -11700.0 -0.88 -1.0287 -0.9778 3211840 TimTec1_004881 NC(=O)C(Cc1ccccc1)NC(=O)c2ccc(Cl)cc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N20 compound treatment 43000.0 1460.0 0.08 40960.0 649.0 0.05 0.0945 0.9667 1014469 TimTec1_004882 CC(=O)Nc1ccccc1N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N21 compound treatment 33880.0 -7660.0 -0.44 29600.0 -10700.0 -0.81 -0.8872 -0.9598 3211841 TimTec1_004883 CC(C)N(Cc1ccccc1)C(=S)Nc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N22 compound treatment 39760.0 -1780.0 -0.1 36120.0 -4190.0 -0.32 -0.2973 -0.8912 3085427 TimTec1_004884 COc1ccccc1/C(=C\C)/C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N23 mock treatment 34280.0 -7260.0 -0.42 39280.0 -1030.0 -0.08 -0.3527 -0.8242 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 N24 mock treatment 35040.0 -6500.0 -0.38 39320.0 -991.0 -0.08 -0.3194 -0.8316 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O01 compound treatment 52000.0 10500.0 0.61 49680.0 9370.0 0.71 0.9299 0.9969 1506163 TimTec1_004885 CCOC(=O)c1c(NC(=O)c2ccccc2)sc3c4OCN(CC=C)Cc4ccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O02 compound treatment 43400.0 1860.0 0.11 42280.0 1970.0 0.15 0.1815 0.9873 1693531 TimTec1_004886 CC1(C)CC(CC(C)(C)N1)NC(=S)NC(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O03 compound treatment 23680.0 -17900.0 -1.03 23000.0 -17300.0 -1.31 -1.6583 -0.9932 3085432 TimTec1_004887 Clc1ccc(NN2C(=O)c3cccc4cc(Br)cc(C2=O)c34)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O04 compound treatment 26400.0 -15100.0 -0.88 30000.0 -10300.0 -0.78 -1.1722 -0.9983 1234657 TimTec1_004888 O=C(CSCc1ccc2nsnc2c1)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O05 compound treatment 37000.0 -4540.0 -0.26 31440.0 -8870.0 -0.67 -0.6609 -0.9163 3211842 TimTec1_004889 CCCN1C(=O)CCN(C(=O)C)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O06 compound treatment 43360.0 1820.0 0.11 39320.0 -991.0 -0.08 0.0215 0.166 1713735 TimTec1_004890 CC1(O)N(C2CC(C)(C)NC(C)(C)C2)C(=O)OC1(C)C3CC4CC3C=C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O07 compound treatment 32360.0 -9180.0 -0.53 33080.0 -7230.0 -0.55 -0.7632 -0.9999 3211843 TimTec1_004891 Cn1cnnc1SCc2c(Cl)cccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O08 compound treatment 35320.0 -6220.0 -0.36 34440.0 -5870.0 -0.44 -0.5691 -0.9946 1260007 TimTec1_004892 CN1CCN(CC1)NC(=S)Nc2ccccc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O09 compound treatment 35400.0 -6140.0 -0.36 36200.0 -4110.0 -0.31 -0.4716 -0.9978 3085435 TimTec1_004893 NN(CCC(=O)NC1CCCCC1)C2=NS(=O)(=O)c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O10 compound treatment 8120.0 -33400.0 -1.94 8960.0 -31400.0 -2.37 -3.0472 -0.9949 3211844 TimTec1_004894 Clc1ccccc1C(=O)NCCOc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O11 compound treatment 31440.0 -10100.0 -0.59 34240.0 -6070.0 -0.46 -0.7388 -0.9928 1622091 TimTec1_004895 Cc1ccc(CNC(=O)CSc2nnc(s2)N3C(=O)c4ccccc4C3=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O12 compound treatment 12200.0 -29300.0 -1.7 12120.0 -28200.0 -2.13 -2.7109 -0.9937 1190874 TimTec1_004896 Cc1ccc(cc1S(=O)(=O)NCc2ccccn2)c3nnc(N4CCCCC4)c5ccccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O13 compound treatment 35800.0 -5740.0 -0.33 32200.0 -8110.0 -0.61 -0.6693 -0.9586 1074879 TimTec1_004897 NC(=O)c1ccc(cc1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O14 compound treatment 29960.0 -11600.0 -0.67 28040.0 -12300.0 -0.93 -1.1313 -0.9873 1529201 TimTec1_004898 O=C1CSC(c2c(nn(c2N1)c3ccccc3)c4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O15 compound treatment 36600.0 -4940.0 -0.29 34560.0 -5750.0 -0.44 -0.5102 -0.9793 1372011 TimTec1_004899 OC(=O)C1(CCC(=O)NCc2ccccc2)CCC(=O)NC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O16 compound treatment 40880.0 -661.0 -0.04 39640.0 -671.0 -0.05 -0.063 -0.9903 1451083 TimTec1_004900 Cc1cccc(NC(=O)CSc2nnc(CCC(=O)O)c(=O)n2N)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O17 compound treatment 17920.0 -23600.0 -1.37 16360.0 -24000.0 -1.81 -2.2497 -0.9904 1606306 TimTec1_004901 CC(=O)Nc1ccccc1c2nc3ccccc3nc2O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O18 compound treatment 27400.0 -14100.0 -0.82 27000.0 -13300.0 -1.01 -1.2918 -0.9947 3211845 TimTec1_004902 Brc1ccc(NC(=O)CSCC(=O)Nc2cccc3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O19 compound treatment 40760.0 -781.0 -0.05 39080.0 -1230.0 -0.09 -0.0979 -0.945 1693543 TimTec1_004903 Cc1nonc1NC2(Nc3nonc3C)C(=O)c4ccccc4C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O20 compound treatment 21920.0 -19600.0 -1.14 25120.0 -15200.0 -1.15 -1.6169 -1.0 1465796 TimTec1_004904 O=C(Sc1nc(c([nH]1)c2ccccc2)c3ccccc3)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O21 compound treatment 41280.0 -261.0 -0.02 38680.0 -1630.0 -0.12 -0.098 -0.7879 1609425 TimTec1_004905 CC(=O)Nc1ncc(CN2CCOCC2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O22 compound treatment 42720.0 1180.0 0.07 39240.0 -1070.0 -0.08 -0.009 -0.0852 1141664 TimTec1_004906 COc1ccc(cc1)S(=O)(=O)c2cc(NS(=O)(=O)c3ccccc3)cc(C(C)C)c2O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O23 mock treatment 43800.0 2260.0 0.13 41840.0 1530.0 0.12 0.1744 0.9981 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 O24 mock treatment 49960.0 8420.0 0.49 42120.0 1810.0 0.14 0.4417 0.8719 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P01 compound treatment 42080.0 539.0 0.03 45400.0 5090.0 0.39 0.2945 0.7619 3085443 TimTec1_004907 Nn1cnn2c(SCc3cccc(c3)C(F)(F)F)nnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P02 compound treatment 25640.0 -15900.0 -0.92 33520.0 -6790.0 -0.51 -1.0149 -0.962 3085445 TimTec1_004908 OC1(CC(=O)c2cccc(c2)n3cnnn3)C(=O)Nc4ccccc41 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P03 compound treatment 18600.0 -22900.0 -1.33 23720.0 -16600.0 -1.26 -1.8279 -0.9996 3211846 TimTec1_004909 NCCN1C(c2c(n[nH]c2C1=O)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P04 compound treatment 23760.0 -17800.0 -1.03 28560.0 -11800.0 -0.89 -1.3574 -0.9973 3211847 TimTec1_004910 Fc1ccc(NC=C2C(=O)NC(=O)NC2=O)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P05 compound treatment 18480.0 -23100.0 -1.34 24640.0 -15700.0 -1.19 -1.7835 -0.9982 3085513 TimTec1_004911 Cc1ccc(c(O)c1)C(O)(c2nc3ccccc3[nH]2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P06 compound treatment 17040.0 -24500.0 -1.42 16640.0 -23700.0 -1.79 -2.2707 -0.9933 1787981 TimTec1_004912 CCn1c2ccccc2c3cc(NC(=O)c4ccc(OC)c(OC)c4)ccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P07 compound treatment 23120.0 -18400.0 -1.07 20360.0 -20000.0 -1.51 -1.8225 -0.9856 3085795 TimTec1_004913 O=C(CC(C(=O)c1ccccc1)n2cccn2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P08 compound treatment 21080.0 -20500.0 -1.19 22280.0 -18000.0 -1.36 -1.8033 -0.9975 3211848 TimTec1_004914 CN(/N=C\1/CCN(C2CCCCC2)C1=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P09 compound treatment 880.0 -40700.0 -2.36 1160.0 -39200.0 -2.96 -3.7613 -0.9935 3085796 TimTec1_004915 O=S(=O)(CCC#N)c1nnnn1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P10 compound treatment 31640.0 -9900.0 -0.57 29800.0 -10500.0 -0.8 -0.9682 -0.9871 1492454 TimTec1_004916 COC(=O)C1=C(N)C(=O)N(C1)c2ccc(cc2)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P11 compound treatment 20280.0 -21300.0 -1.23 21880.0 -18400.0 -1.4 -1.8575 -0.9981 3211849 TimTec1_004917 COc1ccc(cc1)C(=O)NC(Cc2ccccc2)C(=O)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P12 compound treatment 28520.0 -13000.0 -0.75 31160.0 -9150.0 -0.69 -1.0233 -0.9991 1062606 TimTec1_004918 N1=C(C1c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P13 compound treatment 9160.0 -32400.0 -1.88 12600.0 -27700.0 -2.1 -2.8098 -0.9985 3085797 TimTec1_004919 COc1cc(NS(=O)(=O)N2CCCC2)cc(OC)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P14 compound treatment 23080.0 -18500.0 -1.07 22400.0 -17900.0 -1.36 -1.715 -0.9931 3211850 TimTec1_004920 O=C(NCCCc1ccccc1)C2c3ccccc3-c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P15 compound treatment 28640.0 -12900.0 -0.75 29720.0 -10600.0 -0.8 -1.0954 -0.9994 3085798 TimTec1_004921 CNC(=O)C1=C(C)Nc2nc3ccccc3n2C1c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P16 compound treatment 29280.0 -12300.0 -0.71 33800.0 -6510.0 -0.49 -0.8508 -0.984 1558273 TimTec1_004922 OC1C2CN3CC1(CN(C2)CC3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P17 compound treatment 8120.0 -33400.0 -1.94 11600.0 -28700.0 -2.17 -2.9059 -0.9983 3211851 TimTec1_004923 O=C(Cc1ccccc1)Nc2nonc2NC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P18 compound treatment 29160.0 -12400.0 -0.72 24960.0 -15400.0 -1.16 -1.3289 -0.9731 1454261 TimTec1_004924 CCCNC(=O)c1ccc(OC)c(OC(=O)c2ccccc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P19 compound treatment 23120.0 -18400.0 -1.07 24080.0 -16200.0 -1.23 -1.6234 -0.9975 3211852 TimTec1_004925 CN(C)c1nc(N)nc(n1)C2CCCN2S(=O)(=O)c3ccc4ccccc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P20 compound treatment 33320.0 -8220.0 -0.48 31000.0 -9310.0 -0.7 -0.8352 -0.9818 3085799 TimTec1_004926 CS(=O)(=O)c1cccc(Cl)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P21 compound treatment 28800.0 -12700.0 -0.74 28880.0 -11400.0 -0.87 -1.1338 -0.9969 3085800 TimTec1_004927 CC1(C)C(OC(=O)C(C)(C)C1=O)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P22 compound treatment 27040.0 -14500.0 -0.84 29560.0 -10800.0 -0.81 -1.1695 -0.9999 1523811 TimTec1_004928 O=C(N1CCC2(Cc3ccccc3C2=O)CC1)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P23 mock treatment 39440.0 -2100.0 -0.12 35360.0 -4950.0 -0.37 -0.3511 -0.891 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2076 P24 mock treatment 42680.0 1140.0 0.07 35040.0 -5270.0 -0.4 -0.2355 -0.5823 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A01 compound treatment 44960.0 2790.0 0.16 43080.0 -524.0 -0.04 0.0863 0.5184 1644449 TimTec1_004929 COc1cc2CN(C)C(Cc3ccc(OC(=O)C)cc3)c2cc1OBr 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A02 compound treatment 28600.0 -13600.0 -0.79 28680.0 -14900.0 -1.13 -1.3547 -0.9843 3085801 TimTec1_004930 CCn1c(nc2ccccc12)c3nc4ccccc4n3CC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A03 compound treatment 37880.0 -4290.0 -0.25 40120.0 -3480.0 -0.26 -0.3622 -0.9996 3211933 TimTec1_004931 CCOC(=O)/C=C(\C)/NC1CC(C)(C)NC(C)(C)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A04 compound treatment 48640.0 6470.0 0.37 46480.0 2880.0 0.22 0.4191 0.9666 3085802 TimTec1_004932 CO[C@H]1O[C@H](CO)C(=O)C(=C1N)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A05 compound treatment 27280.0 -14900.0 -0.86 33280.0 -10300.0 -0.78 -1.1625 -0.9988 3211934 TimTec1_004933 O=c1sc2ccccc2n1COc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A06 compound treatment 6560.0 -35600.0 -2.06 14960.0 -28600.0 -2.17 -2.992 -0.9997 1219039 TimTec1_004934 CN1CCN(Cc2c3ccccc3cc4ccccc24)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A07 compound treatment 41320.0 -849.0 -0.05 48880.0 5280.0 0.4 0.2476 0.6154 3085803 TimTec1_004935 Cc1noc(C)c1C(=O)Nc2nnc(SCC(=O)O)s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A08 compound treatment 57160.0 15000.0 0.87 51720.0 8120.0 0.61 1.0486 0.9856 1640299 TimTec1_004936 CN(Cc1ccc2OCOc2c1)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A09 compound treatment 37960.0 -4210.0 -0.24 38520.0 -5080.0 -0.38 -0.4445 -0.9758 1531940 TimTec1_004937 OC(C(=O)c1ccccc1)c2c[nH]c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A10 compound treatment 42280.0 111.0 0.01 44560.0 956.0 0.07 0.0557 0.767 3211935 TimTec1_004938 Cn1nnnc1c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A11 compound treatment 31440.0 -10700.0 -0.62 35160.0 -8440.0 -0.64 -0.8915 -0.9999 1334202 TimTec1_004939 CC(NC(=O)OCc1ccccc1)C(=O)Oc2ccc3c(=O)c(Oc4ccccc4)c(C)oc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A12 compound treatment 33320.0 -8850.0 -0.51 42120.0 -1480.0 -0.11 -0.4419 -0.842 1403452 TimTec1_004940 COc1ccccc1c2nn(CN(c3ccccc3)c4ccccc4)c(=S)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A13 compound treatment 47720.0 5550.0 0.32 47320.0 3720.0 0.28 0.4263 0.9978 1575737 TimTec1_004941 O=C(c1ccc2OCCCOc2c1)c3ccc4ccccc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A14 compound treatment 36160.0 -6010.0 -0.35 40240.0 -3360.0 -0.25 -0.4262 -0.9882 1152651 TimTec1_004942 O[C@@H](C1CC2CCN1CC2C=C)c3cnc4ccccc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A15 compound treatment 40960.0 -1210.0 -0.07 42600.0 -1000.0 -0.08 -0.1032 -0.9992 1401869 TimTec1_004943 CC1(C)CC2(CCCN(CC#N)C2)CCO1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A16 compound treatment 41200.0 -969.0 -0.06 48160.0 4560.0 0.34 0.2042 0.5843 1670175 TimTec1_004944 Cc1nc2c(sc3nc4CCCCc4c(c5ccco5)c32)c(=O)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A17 compound treatment 37000.0 -5170.0 -0.3 36480.0 -7120.0 -0.54 -0.593 -0.9615 1247373 TimTec1_004945 Brc1ccnc(N2C(=O)c3ccccc3C2=O)c1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A18 compound treatment 29160.0 -13000.0 -0.75 35440.0 -8160.0 -0.62 -0.9699 -0.9951 3211937 TimTec1_004946 Nc1c(sc2nc(ccc12)c3cccs3)C(=O)c4ccc(Br)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A19 compound treatment 8080.0 -34100.0 -1.98 13520.0 -30100.0 -2.28 -3.0068 -0.9975 3085804 TimTec1_004947 CC(=C)C(=O)N1C(COC1=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A20 compound treatment 45960.0 3790.0 0.22 46800.0 3200.0 0.24 0.3264 0.9988 1254800 TimTec1_004948 CNc1nc(OC)cc(OC)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A21 compound treatment 38920.0 -3250.0 -0.19 47080.0 3480.0 0.26 0.053 0.1637 3211938 TimTec1_004949 O=C(NCc1ccco1)/C(=C/C=C\c2ccccc2)/NC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A22 compound treatment 50120.0 7950.0 0.46 51600.0 8000.0 0.61 0.7537 0.9909 1033657 TimTec1_004950 CS(=O)(=O)c1nc2ccccc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A23 mock treatment 50160.0 7990.0 0.46 54280.0 10700.0 0.81 0.8988 0.9651 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 A24 mock treatment 55560.0 13400.0 0.78 58480.0 14900.0 1.13 1.3449 0.9835 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B01 compound treatment 39880.0 -2290.0 -0.13 47160.0 3560.0 0.27 0.0966 0.3218 3211939 TimTec1_004951 CC(C)(C)C(=O)Nc1nccs1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B02 compound treatment 25000.0 -17200.0 -0.99 31200.0 -12400.0 -0.94 -1.3673 -0.9996 3211940 TimTec1_004952 O=S(=O)(/N=C(\Nc1cccc2ccccc12)/c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B03 compound treatment 36320.0 -5850.0 -0.34 49040.0 5440.0 0.41 0.0514 0.0963 1143395 TimTec1_004953 CN(C)c1nc2n(C)c(=O)[nH]c(=O)c2[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B04 compound treatment 37120.0 -5050.0 -0.29 41520.0 -2080.0 -0.16 -0.3184 -0.958 3085810 TimTec1_004954 CCOC(=O)c1cn(nc1C(F)(F)F)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B05 compound treatment 35760.0 -6410.0 -0.37 42840.0 -764.0 -0.06 -0.3034 -0.8075 3211941 TimTec1_004955 CCc1[o+]c(cc2CCCCc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B06 compound treatment 28720.0 -13400.0 -0.78 38360.0 -5240.0 -0.4 -0.8316 -0.951 1673469 TimTec1_004956 Cc1nn(c2ccccc2)c3sc(cc13)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B07 compound treatment 14000.0 -28200.0 -1.63 20520.0 -23100.0 -1.75 -2.3896 -0.9994 3211942 TimTec1_004957 O=C/1CCCC\C1=C\Nc2cccc(N/C=C\3/CCCCC3=O)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B08 compound treatment 36200.0 -5970.0 -0.35 46680.0 3080.0 0.23 -0.0799 -0.1916 1541165 TimTec1_004958 Cc1nonc1NC(=O)Nc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B09 compound treatment 800.0 -41400.0 -2.4 1400.0 -42200.0 -3.19 -3.9537 -0.99 1429667 TimTec1_004959 COc1cccc(C(N2CCCC2)c3cc4OCOc4cc3O)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B10 compound treatment 19360.0 -22800.0 -1.32 26360.0 -17200.0 -1.31 -1.8574 -1.0 3085814 TimTec1_004960 CC(=O)Nc1sc(C)c(C)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B11 compound treatment 30760.0 -11400.0 -0.66 33480.0 -10100.0 -0.77 -1.0093 -0.9973 1366449 TimTec1_004961 CN(C)c1ccc(cc1)C2CC(C)(Oc3cc4OCOc4cc23)N5CCCC5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B12 compound treatment 32920.0 -9250.0 -0.54 40800.0 -2800.0 -0.21 -0.529 -0.9178 3085816 TimTec1_004962 CC1=NNC(=O)C1C(C(C#N)C#N)c2ccccc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B13 compound treatment 48680.0 6510.0 0.38 48760.0 5160.0 0.39 0.5427 0.9999 1019517 TimTec1_004963 COc1cc(cc(OC)c1O)C2C3C(COC3=O)Cc4c(O)c5OCOc5cc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B14 compound treatment 16400.0 -25800.0 -1.49 19120.0 -24500.0 -1.85 -2.3662 -0.9943 1563233 TimTec1_004964 CCSc1nc2n(C)c(=O)[nH]c(=O)c2n1Cc3ccc(C)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B15 compound treatment 42240.0 71.3 0.0 49160.0 5560.0 0.42 0.3003 0.714 3085858 TimTec1_004965 COc1cnc(SC)n(C)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B16 compound treatment 29960.0 -12200.0 -0.71 37400.0 -6200.0 -0.47 -0.8322 -0.9802 1621047 TimTec1_004966 Cn1c(=O)[nH]c(=O)c2n(CC(O)COc3ccc(Cl)cc3Cl)c(Br)nc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B17 compound treatment 37160.0 -5010.0 -0.29 48840.0 5240.0 0.4 0.0751 0.1528 1547656 TimTec1_004967 CCOc1nc2ccccc2c(=O)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B18 compound treatment 43600.0 1430.0 0.08 48400.0 4800.0 0.36 0.3154 0.8468 1446595 TimTec1_004968 CC(C)c1oc2cc(O)ccc2c(=O)c1c3nc4ccccc4n3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B19 compound treatment 47280.0 5110.0 0.3 54240.0 10600.0 0.81 0.7787 0.9077 2747 TimTec1_004969 Nc1ccn([C@H]2CC[C@@H](CO)O2)c(=O)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B20 compound treatment 35200.0 -6970.0 -0.4 47880.0 4280.0 0.32 -0.0566 -0.1094 1295276 TimTec1_004970 NC(=S)c1[nH]nc2c1[nH]c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B21 compound treatment 37040.0 -5130.0 -0.3 42360.0 -1240.0 -0.09 -0.2767 -0.8877 1170984 TimTec1_004971 Cc1ccc(SC(CC(=O)c2ccc(cc2)C(C)(C)C)C(=O)O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B22 compound treatment 34840.0 -7330.0 -0.42 40960.0 -2640.0 -0.2 -0.4417 -0.9411 3085864 TimTec1_004972 CCCCC1SC(=NNC1=O)/N=C/c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B23 mock treatment 49440.0 7270.0 0.42 51600.0 8000.0 0.61 0.7259 0.9843 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 B24 mock treatment 53600.0 11400.0 0.66 51120.0 7520.0 0.57 0.8706 0.9971 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C01 compound treatment 25320.0 -16800.0 -0.98 36680.0 -6920.0 -0.52 -1.0608 -0.9575 1262842 TimTec1_004973 CCOC(=O)C1(CCN(c2ccccc2C1=O)S(=O)(=O)c3ccc(C)cc3)C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C02 compound treatment 41960.0 -209.0 -0.01 49920.0 6320.0 0.48 0.3295 0.689 1630883 TimTec1_004974 Cn1c(nc2ccccc12)P(=O)(C)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C03 compound treatment 35880.0 -6290.0 -0.36 42320.0 -1280.0 -0.1 -0.3263 -0.8654 3211943 TimTec1_004975 CCc1cccc(NC(=O)OC2CCN(C)CC2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C04 compound treatment 25520.0 -16600.0 -0.96 22320.0 -21300.0 -1.61 -1.8213 -0.9699 3085867 TimTec1_004976 Oc1ccccc1/N=C/c2ccncc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C05 compound treatment 32880.0 -9290.0 -0.54 41040.0 -2560.0 -0.19 -0.5178 -0.905 1684419 TimTec1_004977 CC(=O)Nc1ccc2n(CC=C)c(=O)sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C06 compound treatment 34360.0 -7810.0 -0.45 43560.0 -43.8 0.0 -0.3223 -0.7123 3085869 TimTec1_004978 CN1CCN(Cc2c(Cl)cccc2Cl)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C07 compound treatment 32200.0 -9970.0 -0.58 41400.0 -2200.0 -0.17 -0.5264 -0.8755 1544605 TimTec1_004979 Cc1ccc(F)c2[nH]cc3c(=O)n(nc3c12)c4ccccc4Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C08 compound treatment 40480.0 -1690.0 -0.1 46160.0 2560.0 0.19 0.0676 0.3119 1692460 TimTec1_004980 CSc1ccc(CN2CCOCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C09 compound treatment 43120.0 951.0 0.06 49920.0 6320.0 0.48 0.377 0.7834 1697399 TimTec1_004981 CC(Oc1ccc2c(cc(=O)oc2c1)c3ccccc3)C(=O)ON4C(=O)CCC4=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C10 compound treatment 33680.0 -8490.0 -0.49 42640.0 -964.0 -0.07 -0.3994 -0.8032 1553247 TimTec1_004982 Nc1nc(c(Cl)s1)S(=O)(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C11 compound treatment 23600.0 -18600.0 -1.08 29640.0 -14000.0 -1.06 -1.5081 -1.0 1170357 TimTec1_004983 CC(C)(C)OC(=O)N1CCCC1C(=O)Oc2ccc3c(=O)c(coc3c2)c4ccc5OCCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C12 compound treatment 32880.0 -9290.0 -0.54 39960.0 -3640.0 -0.28 -0.5756 -0.9518 1143084 TimTec1_004984 O=C(CSCc1c[nH]c2ccccc12)Nc3ccc4ccccc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C13 compound treatment 44000.0 1830.0 0.11 45440.0 1840.0 0.14 0.1733 0.9911 1113621 TimTec1_004985 S=C(N1CCOCC1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C14 compound treatment 25200.0 -17000.0 -0.98 39520.0 -4080.0 -0.31 -0.9138 -0.8866 3211944 TimTec1_004986 OC[C@H]1[C@@H](C[C@@H]2OC(=O)C[C@H]12)OC(=O)c3ccc(cc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C15 compound treatment 41120.0 -1050.0 -0.06 48920.0 5320.0 0.4 0.2416 0.5936 1673684 TimTec1_004987 COc1nc(nc(n1)N2CCc3ccccc23)N4CCc5ccccc45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C16 compound treatment 28320.0 -13800.0 -0.8 34120.0 -9480.0 -0.72 -1.075 -0.9985 3085875 TimTec1_004988 CCc1nc(SC)c(C#N)c2CCCCc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C17 compound treatment 42760.0 591.0 0.03 42040.0 -1560.0 -0.12 -0.0595 -0.4827 1436730 TimTec1_004989 CC1(C)CC(=O)C(C(=C1)O)C2(O)C(=O)c3ccccc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C18 compound treatment 36480.0 -5690.0 -0.33 47640.0 4040.0 0.31 -0.017 -0.0379 1271503 TimTec1_004990 COc1ccc(OC)c(c1)C2C(=C(N)Oc3cc(C)oc(=O)c23)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C19 compound treatment 40240.0 -1930.0 -0.11 44960.0 1360.0 0.1 -0.0064 -0.0423 3085916 TimTec1_004991 CC[n+]1ccc(/C=C/c2ccc(OC)c(OC)c2OC)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C20 compound treatment 42520.0 351.0 0.02 50120.0 6520.0 0.49 0.3632 0.7357 3085918 TimTec1_004992 Nc1nc(OCC(F)(F)F)cc(n1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C21 compound treatment 41680.0 -489.0 -0.03 44280.0 676.0 0.05 0.0162 0.2765 3211998 TimTec1_004993 CC1CCN(CC1)C(=O)/C(=C/C=C\c2ccccc2)/NC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C22 compound treatment 45320.0 3150.0 0.18 48680.0 5080.0 0.38 0.4008 0.9421 3085922 TimTec1_004994 Cc1nc2ccccc2c(=O)n1/N=C/c3ccc4ncccc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C23 mock treatment 44760.0 2590.0 0.15 49040.0 5440.0 0.41 0.3971 0.9066 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 C24 mock treatment 46520.0 4350.0 0.25 52400.0 8800.0 0.67 0.6491 0.9117 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D01 compound treatment 38800.0 -3370.0 -0.2 46280.0 2680.0 0.2 0.0052 0.0186 1018493 TimTec1_004995 CC(C)C(N1C(=O)c2ccccc2C1=O)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D02 compound treatment 37920.0 -4250.0 -0.25 40080.0 -3520.0 -0.27 -0.3627 -0.9992 1571869 TimTec1_004996 Cc1ccc(cc1)S(=O)(=O)NC(=O)SC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D03 compound treatment 21800.0 -20400.0 -1.18 32520.0 -11100.0 -0.84 -1.4277 -0.986 1513997 TimTec1_004997 Cc1cccc(Oc2ncc(F)c(Oc3cccc(C)c3)n2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D04 compound treatment 35080.0 -7090.0 -0.41 43000.0 -604.0 -0.05 -0.3227 -0.781 1365828 TimTec1_004998 CSc1nc2NC(=CC(c3ccccc3)n2n1)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D05 compound treatment 34560.0 -7610.0 -0.44 41920.0 -1680.0 -0.13 -0.4018 -0.8757 3085925 TimTec1_004999 CCc1[o+]c(cc2cc(OC)c(OC)cc12)c3ccc(OC)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D06 compound treatment 8240.0 -33900.0 -1.97 22600.0 -21000.0 -1.59 -2.5142 -0.9945 1921582 TimTec1_005000 Cc1cc(C)n(n1)C(=O)c2ccc(cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D07 compound treatment 32440.0 -9730.0 -0.56 43280.0 -324.0 -0.02 -0.4159 -0.7372 3211999 TimTec1_005001 O=C/1CCCC\C1=C\Nc2ccc(N/C=C\3/CCCCC3=O)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D08 compound treatment 35440.0 -6730.0 -0.39 45360.0 1760.0 0.13 -0.1817 -0.441 1174633 TimTec1_005002 CC(NC(=O)c1cccc(N)c1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D09 compound treatment 26960.0 -15200.0 -0.88 38880.0 -4720.0 -0.36 -0.8759 -0.9211 1210964 TimTec1_005003 COc1ccc(cc1)C(C)c2cc3OCOc3cc2OCC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D10 compound treatment 25880.0 -16300.0 -0.94 30480.0 -13100.0 -0.99 -1.3698 -0.9997 3212000 TimTec1_005004 Clc1ccc(NC(=O)c2cccs2)nc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D11 compound treatment 600.0 -41600.0 -2.41 1040.0 -42600.0 -3.22 -3.9812 -0.9897 1124331 TimTec1_005005 CN(C)c1ccc(cc1)C(N2CCCCC2)c3cc4OCOc4cc3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D12 compound treatment 34320.0 -7850.0 -0.45 41240.0 -2360.0 -0.18 -0.4481 -0.9169 1007160 TimTec1_005006 NC(=N)Nc1nc2ccccc2[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D13 compound treatment 40960.0 -1210.0 -0.07 49400.0 5800.0 0.44 0.2607 0.5868 3085929 TimTec1_005007 Cn1c(=O)n(C)c2nc([nH]c2c1=O)[n+]3ccc(cc3)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D14 compound treatment 40040.0 -2130.0 -0.12 48480.0 4880.0 0.37 0.1738 0.4466 1272092 TimTec1_005008 Cn1c(=O)[nH]c(=O)c2n(CC(O)COc3ccc4ccccc4c3)c(S)nc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D15 compound treatment 40520.0 -1650.0 -0.1 51080.0 7480.0 0.57 0.3326 0.5795 1371696 TimTec1_005009 OC(=O)Cn1ccsc1=N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D16 compound treatment 31280.0 -10900.0 -0.63 37760.0 -5840.0 -0.44 -0.7589 -0.9849 3085931 TimTec1_005010 CCOC(=O)N(c1ccccc1)S(=O)(=O)c2ccccc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D17 compound treatment 42360.0 191.0 0.01 47000.0 3400.0 0.26 0.1896 0.7369 1391232 TimTec1_005011 CCOc1nc2ccccc2c(=O)n1CCO 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D18 compound treatment 34920.0 -7250.0 -0.42 40080.0 -3520.0 -0.27 -0.4856 -0.976 1600779 TimTec1_005012 NC(=O)c1c(oc2ccc(O)cc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D19 compound treatment 38000.0 -4170.0 -0.24 45880.0 2280.0 0.17 -0.049 -0.165 3085934 TimTec1_005013 Cn1cnnc1SC/C=C/c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D20 compound treatment 22360.0 -19800.0 -1.15 31920.0 -11700.0 -0.88 -1.4369 -0.9917 3212001 TimTec1_005014 N(=c/1\[nH]c2c(ccc3ccccc23)s1)\c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D21 compound treatment 42480.0 311.0 0.02 45680.0 2080.0 0.16 0.1239 0.7831 1597367 TimTec1_005015 OC(=O)C(CC(=O)c1ccc(Cl)cc1)SCc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D22 compound treatment 33240.0 -8930.0 -0.52 44000.0 396.0 0.03 -0.3446 -0.665 3212002 TimTec1_005016 N1N=C(SC=C1c2ccccc2)/N=C/c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D23 mock treatment 45040.0 2870.0 0.17 50280.0 6680.0 0.51 0.475 0.8927 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 D24 mock treatment 48560.0 6390.0 0.37 49840.0 6240.0 0.47 0.5956 0.9928 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E01 compound treatment 26000.0 -16200.0 -0.94 32760.0 -10800.0 -0.82 -1.2428 -0.9978 1071315 TimTec1_005017 COc1ccc2c3CCCC(=O)c3ccc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E02 compound treatment 26000.0 -16200.0 -0.94 31680.0 -11900.0 -0.9 -1.3006 -0.9998 1454628 TimTec1_005018 Oc1ccc(C(=O)COc2ccccc2)c(O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E03 compound treatment 21960.0 -20200.0 -1.17 29880.0 -13700.0 -1.04 -1.5625 -0.9982 3085938 TimTec1_005019 CCOC(=O)Nc1nc2c(Cl)cccc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E04 compound treatment 39880.0 -2290.0 -0.13 43640.0 36.3 0.0 -0.0918 -0.6923 1030338 TimTec1_005020 COC(=O)c1nc[nH]c1C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E05 compound treatment 24560.0 -17600.0 -1.02 34720.0 -8880.0 -0.67 -1.1969 -0.9795 3085974 TimTec1_005021 CCOC(=O)n1c(=O)sc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E06 compound treatment 32160.0 -10000.0 -0.58 45320.0 1720.0 0.13 -0.3182 -0.5354 3085976 TimTec1_005022 CN1CCN(CC2CCC=CC2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E07 compound treatment 34720.0 -7450.0 -0.43 43720.0 116.0 0.01 -0.2989 -0.6925 1140829 TimTec1_005023 CN(C)S(=O)(=O)c1ccc(C#N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E08 compound treatment 38120.0 -4050.0 -0.23 44960.0 1360.0 0.1 -0.0933 -0.3643 1363499 TimTec1_005024 CCCN(CCO)CC1CCC=CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E09 compound treatment 32040.0 -10100.0 -0.59 41680.0 -1920.0 -0.15 -0.5179 -0.8566 1427526 TimTec1_005025 O=c1c(Oc2ccccc2)coc3cc(OCc4ccccc4)ccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E10 compound treatment 41240.0 -929.0 -0.05 45720.0 2120.0 0.16 0.0752 0.4451 1637231 TimTec1_005026 COC1(CCCC2(CCC1)C(=O)O)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E11 compound treatment 14960.0 -27200.0 -1.58 22640.0 -21000.0 -1.59 -2.2368 -1.0 1442714 TimTec1_005027 CCOC(=O)c1ccc(o1)c2coc3cc(O)cc(O)c3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E12 compound treatment 28080.0 -14100.0 -0.82 40040.0 -3560.0 -0.27 -0.7679 -0.8933 1234769 TimTec1_005028 COc1ccc(cc1)c2cc(NC(=O)Nc3ccccc3)n(n2)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E13 compound treatment 29680.0 -12500.0 -0.72 41280.0 -2320.0 -0.18 -0.636 -0.8541 1381033 TimTec1_005029 COc1cc(Cl)cc(C(=O)O)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E14 compound treatment 23360.0 -18800.0 -1.09 27520.0 -16100.0 -1.22 -1.6314 -0.9985 1056436 TimTec1_005030 CC(C)c1nc2nc(N)nc(N)c2nc1C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E15 compound treatment 31760.0 -10400.0 -0.6 36840.0 -6760.0 -0.51 -0.7884 -0.9967 1074483 TimTec1_005031 CCN(C(=O)Nc1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E16 compound treatment 30000.0 -12200.0 -0.71 31920.0 -11700.0 -0.88 -1.1239 -0.9937 3212003 TimTec1_005032 Cc1s/c(=N/c2ccccc2)/[nH]c1c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E17 compound treatment 8240.0 -33900.0 -1.97 12880.0 -30700.0 -2.33 -3.0345 -0.9965 3212004 TimTec1_005033 C(=N/c1cc(nn1c2ccccc2)c3ccccc3)\c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E18 compound treatment 36200.0 -5970.0 -0.35 41360.0 -2240.0 -0.17 -0.3646 -0.9464 3085984 TimTec1_005034 COc1ccc(/C=C/2\C(=NC(=NC2=O)S)O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E19 compound treatment 37400.0 -4770.0 -0.28 44560.0 956.0 0.07 -0.1442 -0.5048 3212005 TimTec1_005035 CCc1ccc(NC(=O)CSc2nncn2C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E20 compound treatment 43040.0 871.0 0.05 50360.0 6760.0 0.51 0.3973 0.7731 3085985 TimTec1_005036 Cc1cc(nc(N)n1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E21 compound treatment 33800.0 -8370.0 -0.48 42080.0 -1520.0 -0.12 -0.4244 -0.8516 3212006 TimTec1_005037 Cc1ccc(cc1)C(=O)N/C(=C\C=C/c2ccccc2)/C(=O)NCC3CCCO3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E22 compound treatment 38360.0 -3810.0 -0.22 42360.0 -1240.0 -0.09 -0.2226 -0.9279 3085988 TimTec1_005038 Oc1ccc(/C=N\C2c3ccccc3-c4ccccc24)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E23 mock treatment 47760.0 5590.0 0.32 50200.0 6600.0 0.5 0.5821 0.9781 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 E24 mock treatment 45520.0 3350.0 0.19 44800.0 1200.0 0.09 0.2013 0.9397 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F01 compound treatment 12920.0 -29200.0 -1.69 15600.0 -28000.0 -2.12 -2.6971 -0.9938 3212007 TimTec1_005039 C[n+]1c(/C=C/Nc2ccccc2)sc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F02 compound treatment 40960.0 -1210.0 -0.07 40600.0 -3000.0 -0.23 -0.2103 -0.8839 3085989 TimTec1_005040 Cn1c(=O)[nH]c(=O)c2n3CCCC(c3nc12)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F03 compound treatment 38600.0 -3570.0 -0.21 43800.0 196.0 0.01 -0.1357 -0.6546 3212008 TimTec1_005041 Clc1ccc(cc1)c2nc3sc4CCCCc4c3c(=O)[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F04 compound treatment 26240.0 -15900.0 -0.92 36600.0 -7000.0 -0.53 -1.0274 -0.9654 1188459 TimTec1_005042 OC(CN(Cc1ccccc1)Cc2ccccc2)Cn3c4ccccc4c5ccccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F05 compound treatment 27320.0 -14800.0 -0.86 37280.0 -6320.0 -0.48 -0.9468 -0.9617 3085992 TimTec1_005043 COC(=O)C(Cc1c[nH]c2ccccc12)/N=C/c3cc(Cl)cc(Cl)c3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F06 compound treatment 23680.0 -18500.0 -1.07 32840.0 -10800.0 -0.81 -1.3336 -0.9909 1464296 TimTec1_005044 CCCOC(=O)c1c(N)sc2CCCCc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F07 compound treatment 34000.0 -8170.0 -0.47 50120.0 6520.0 0.49 0.0141 0.0207 3085994 TimTec1_005045 CC1(C)CC(=O)C/C(=N\CC(=O)O)/C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F08 compound treatment 30200.0 -12000.0 -0.69 42400.0 -1200.0 -0.09 -0.5548 -0.7932 3212009 TimTec1_005046 COc1cccc(c1)c2nnc(o2)c3ccc(NC(=O)C(F)(F)F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F09 compound treatment 38520.0 -3650.0 -0.21 45720.0 2120.0 0.16 -0.0362 -0.1365 1692415 TimTec1_005047 COc1ccccc1C(C2=C(O)COC2=O)c3cc4OCOc4cc3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F10 compound treatment 32920.0 -9250.0 -0.54 44480.0 876.0 0.07 -0.332 -0.6149 1261046 TimTec1_005048 O=C(Nc1nccs1)c2ccccc2c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F11 compound treatment 9120.0 -33000.0 -1.91 14480.0 -29100.0 -2.2 -2.9128 -0.9975 1427389 TimTec1_005049 Oc1cc2OCOc2cc1C(Nc3ccccn3)c4ccc5OCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F12 compound treatment 22880.0 -19300.0 -1.12 35080.0 -8520.0 -0.65 -1.2464 -0.9659 1182617 TimTec1_005050 CC(C)(C)C(=O)C1C2CCC1C(O)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F13 compound treatment 38120.0 -4050.0 -0.23 47160.0 3560.0 0.27 0.0245 0.0685 1471843 TimTec1_005051 Cn1c(SCC(=O)OCC(=O)c2ccc(Br)cc2)nc3n(C)c(=O)[nH]c(=O)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F14 compound treatment 35800.0 -6370.0 -0.37 40440.0 -3160.0 -0.24 -0.4303 -0.9781 1227820 TimTec1_005052 CC1CCN(CC1)C(=O)COc2ccc(Br)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F15 compound treatment 44360.0 2190.0 0.13 49200.0 5600.0 0.42 0.3893 0.8803 1067946 TimTec1_005053 Cc1nnc(o1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F16 compound treatment 32520.0 -9650.0 -0.56 36160.0 -7440.0 -0.56 -0.7937 -1.0 3212010 TimTec1_005054 CCOC(=O)N(c1ccccc1)S(=O)(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F17 compound treatment 40760.0 -1410.0 -0.08 47080.0 3480.0 0.26 0.1283 0.4659 1743351 TimTec1_005055 CCOC(=O)CNc1nc(N)n[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F18 compound treatment 38720.0 -3450.0 -0.2 40040.0 -3560.0 -0.27 -0.332 -0.9891 3212069 TimTec1_005056 Sc1nnc2c3cc(Br)ccc3n(CC=C)c2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F19 compound treatment 39040.0 -3130.0 -0.18 43200.0 -404.0 -0.03 -0.1498 -0.8148 3086039 TimTec1_005057 OC(=O)c1ccc(Sc2ccccn2)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F20 compound treatment 34760.0 -7410.0 -0.43 38560.0 -5040.0 -0.38 -0.5735 -0.9983 3212070 TimTec1_005058 CC1SC(=NNC1=O)/N=C/c2ccc(cc2)N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F21 compound treatment 42640.0 471.0 0.03 48760.0 5160.0 0.39 0.2953 0.7547 1338088 TimTec1_005059 Cc1ccc(cc1)C(=O)CC(SC2CCCCC2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F22 compound treatment 39360.0 -2810.0 -0.16 38680.0 -4920.0 -0.37 -0.3786 -0.931 3212071 TimTec1_005060 Cc1c(/N=c/2\scc(c3ccccc3)n2c4ccccc4)c(=O)n(c5ccccc5)n1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F23 mock treatment 43240.0 1070.0 0.06 42440.0 -1160.0 -0.09 -0.0184 -0.1708 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 F24 mock treatment 45280.0 3110.0 0.18 42920.0 -684.0 -0.05 0.0909 0.4845 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G01 compound treatment 38560.0 -3610.0 -0.21 38200.0 -5400.0 -0.41 -0.4371 -0.9515 3086042 TimTec1_005061 CCOC(=O)C1=C(O)C(=O)N(C1)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G02 compound treatment 30480.0 -11700.0 -0.68 35480.0 -8120.0 -0.61 -0.9137 -0.9988 3212072 TimTec1_005062 CN1C(=O)N(C)C(=O)C(=Cc2ccccc2)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G03 compound treatment 40600.0 -1570.0 -0.09 41680.0 -1920.0 -0.15 -0.1672 -0.9743 1400641 TimTec1_005063 C=CCON1C(=O)C2C3OC(C=C3)C2C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G04 compound treatment 34520.0 -7650.0 -0.44 40960.0 -2640.0 -0.2 -0.4549 -0.9355 3212073 TimTec1_005064 C[N+](C)(C)[C@H]1C(O)O[C@@H]2C(O)CO[C@H]12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G05 compound treatment 32920.0 -9250.0 -0.54 39480.0 -4120.0 -0.31 -0.5996 -0.9669 1411352 TimTec1_005065 C(N1CCN(CC1)C(c2ccccc2)c3ccccc3)C4(OCCO4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G06 compound treatment 34960.0 -7210.0 -0.42 39200.0 -4400.0 -0.33 -0.531 -0.9938 3212074 TimTec1_005066 CN1CCN(Cc2ccc[nH]2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G07 compound treatment 13320.0 -28800.0 -1.67 24000.0 -19600.0 -1.48 -2.2312 -0.9982 3086046 TimTec1_005067 COc1ccc(cc1)c2nc3ccsc3c(=O)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G08 compound treatment 30600.0 -11600.0 -0.67 42880.0 -724.0 -0.05 -0.5127 -0.7624 1405970 TimTec1_005068 CN(C)CCN(CC1CC2CC1C=C2)Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G09 compound treatment 35800.0 -6370.0 -0.37 44440.0 836.0 0.06 -0.2162 -0.5774 1084368 TimTec1_005069 OC(=O)C1CSC2(CCCCC2)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G10 compound treatment 24040.0 -18100.0 -1.05 28560.0 -15000.0 -1.14 -1.5479 -0.9992 1144864 TimTec1_005070 CCN1C(=O)c2cccc3c(NC(=O)C)ccc1c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G11 compound treatment 34520.0 -7650.0 -0.44 46080.0 2480.0 0.19 -0.1808 -0.3758 3212075 TimTec1_005071 Cc1[nH]cnc1C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G12 compound treatment 23960.0 -18200.0 -1.05 33400.0 -10200.0 -0.77 -1.2921 -0.9883 1717981 TimTec1_005072 Oc1ccc(=O)n(CN(c2ccccc2)c3ccccc3)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G13 compound treatment 32440.0 -9730.0 -0.56 42680.0 -924.0 -0.07 -0.448 -0.7888 1174597 TimTec1_005073 CCc1cc2OCCOc2cc1C(=O)CCN3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G14 compound treatment 38840.0 -3330.0 -0.19 37840.0 -5760.0 -0.44 -0.4449 -0.9326 3086051 TimTec1_005074 CC1CC(C)(C)N=C(O1)C(=C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G15 compound treatment 34320.0 -7850.0 -0.45 42680.0 -924.0 -0.07 -0.371 -0.8064 1409343 TimTec1_005075 O=C1N(CNN2CCCc3ccccc23)C(=O)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G16 compound treatment 36400.0 -5770.0 -0.33 38960.0 -4640.0 -0.35 -0.4849 -0.9997 1629224 TimTec1_005076 CSc1ccc(cc1)c2[nH]c(=N)sc2c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G17 compound treatment 1560.0 -40600.0 -2.35 1120.0 -42500.0 -3.22 -3.9376 -0.9882 1378559 TimTec1_005077 CCN(CC)c1nc(NC(C)(C)C)nc(NC(C)(C)C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G18 compound treatment 40600.0 -1570.0 -0.09 46720.0 3120.0 0.24 0.1025 0.4056 1733553 TimTec1_005078 Oc1nc2CCCc2c(=O)n1C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G19 compound treatment 12960.0 -29200.0 -1.69 18840.0 -24800.0 -1.87 -2.5221 -0.9987 3086099 TimTec1_005079 Clc1ccc(SCC(=O)Nc2cccc(Cl)c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G20 compound treatment 28800.0 -13400.0 -0.77 31360.0 -12200.0 -0.93 -1.203 -0.996 1367022 TimTec1_005080 Oc1ccccc1OCC(=O)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G21 compound treatment 37040.0 -5130.0 -0.3 43760.0 156.0 0.01 -0.2018 -0.6784 3212076 TimTec1_005081 O=C(NCC1CCCO1)/C(=C/c2ccccc2)/NC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G22 compound treatment 39960.0 -2210.0 -0.13 42280.0 -1320.0 -0.1 -0.1613 -0.9927 3086101 TimTec1_005082 O=S(=O)(c1ccc(/N=C\c2ccncc2)cc1)c3ccc(/N=C\c4ccncc4)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G23 mock treatment 37840.0 -4330.0 -0.25 47960.0 4360.0 0.33 0.0558 0.1347 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 G24 mock treatment 41320.0 -849.0 -0.05 40160.0 -3440.0 -0.26 -0.2191 -0.8259 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H01 compound treatment 10280.0 -31900.0 -1.85 12000.0 -31600.0 -2.39 -2.998 -0.9918 3212077 TimTec1_005083 CC[n+]1c(/C=C/Nc2ccccc2)sc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H02 compound treatment 31760.0 -10400.0 -0.6 38400.0 -5200.0 -0.39 -0.705 -0.9787 1673284 TimTec1_005084 CC(=C)c1cccc(c1)C(C)(C)NC(=O)NCC2CCCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H03 compound treatment 35880.0 -6290.0 -0.36 44680.0 1080.0 0.08 -0.2 -0.5358 3086104 TimTec1_005085 Clc1nc(nc2sc3CCCCc3c12)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H04 compound treatment 35920.0 -6250.0 -0.36 40680.0 -2920.0 -0.22 -0.4125 -0.9721 3212078 TimTec1_005086 CCN1C(=O)/C(=C/2\SC(=S)N(NC(=O)c3ccccc3)C2=O)/c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H05 compound treatment 36680.0 -5490.0 -0.32 44520.0 916.0 0.07 -0.1758 -0.5402 1072337 TimTec1_005087 CCCC(=O)Oc1ccc2c(C)cc(=O)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H06 compound treatment 12280.0 -29900.0 -1.73 15200.0 -28400.0 -2.15 -2.7448 -0.9942 1560027 TimTec1_005088 Cc1ccccc1C(=O)Nc2cc3CCCCc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H07 compound treatment 31920.0 -10200.0 -0.59 38080.0 -5520.0 -0.42 -0.7155 -0.9853 3086107 TimTec1_005089 OC(=O)c1ccc(/N=C/c2cccnc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H08 compound treatment 25000.0 -17200.0 -0.99 37000.0 -6600.0 -0.5 -1.0568 -0.9493 1735547 TimTec1_005090 O=C1CCC(=O)N1c2ccc3c(c2)oc4ccccc43 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H09 compound treatment 34400.0 -7770.0 -0.45 45440.0 1840.0 0.14 -0.22 -0.467 1148656 TimTec1_005091 COc1ccccc1C(C2=C(COC2=O)OC(=O)C)c3cc4OCOc4cc3OC(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H10 compound treatment 34000.0 -8170.0 -0.47 41280.0 -2320.0 -0.18 -0.459 -0.9091 3212079 TimTec1_005092 Fc1ccccc1NC(=O)CSCC(=O)Nc2ccc3ccccc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H11 compound treatment 2000.0 -40200.0 -2.33 2120.0 -41500.0 -3.14 -3.866 -0.9891 1232879 TimTec1_005093 COc1ccc(cc1)C(N2CCOCC2)c3cc4OCOc4cc3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H12 compound treatment 28960.0 -13200.0 -0.77 33880.0 -9720.0 -0.74 -1.0616 -0.9998 1704797 TimTec1_005094 O=C(CCc1ccccc1)N2CCN(CC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H13 compound treatment 29080.0 -13100.0 -0.76 31640.0 -12000.0 -0.91 -1.1766 -0.9961 1531317 TimTec1_005095 CCCn1c(nc2n(C)c(=O)[nH]c(=O)c12)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H14 compound treatment 31800.0 -10400.0 -0.6 34960.0 -8640.0 -0.65 -0.8874 -0.9991 1213903 TimTec1_005096 CC(C)(C)c1ccccc1OCC(=O)Nc2ccc(OCc3ccccc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H15 compound treatment 35160.0 -7010.0 -0.41 40760.0 -2840.0 -0.22 -0.4393 -0.9559 3212080 TimTec1_005097 CSc1nc(N)c(C#N)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H16 compound treatment 35440.0 -6730.0 -0.39 37680.0 -5920.0 -0.45 -0.5927 -0.9976 1603630 TimTec1_005098 CCOC(=O)N(c1ccc(OC)cc1)S(=O)(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H17 compound treatment 34200.0 -7970.0 -0.46 42440.0 -1160.0 -0.09 -0.3888 -0.8271 1625154 TimTec1_005099 CCn1c(=O)c(C(=O)NC)c(O)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H18 compound treatment 11360.0 -30800.0 -1.78 16040.0 -27600.0 -2.09 -2.7375 -0.997 3212081 TimTec1_005100 COc1ccc(c2n[nH]c(C)c2Oc3ccccc3)c(O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H19 compound treatment 39640.0 -2530.0 -0.15 45960.0 2360.0 0.18 0.0225 0.0976 1424497 TimTec1_005101 CCOC(=O)C1=C(C)NC(=O)NC1c2c(Cl)nc3c(C)cccn3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H20 compound treatment 39920.0 -2250.0 -0.13 46840.0 3240.0 0.24 0.0811 0.2923 3212082 TimTec1_005102 COc1ccc(/C=N/C2=NNC(=O)CS2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H21 compound treatment 45480.0 3310.0 0.19 44160.0 556.0 0.04 0.1654 0.8423 1547308 TimTec1_005103 CC(C)(C)c1ccc(cc1)C(=O)CC(SC2CCCCC2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H22 compound treatment 37200.0 -4970.0 -0.29 33280.0 -10300.0 -0.78 -0.7561 -0.9079 3212083 TimTec1_005104 COc1ccc(/C=N/C2=NNC(=CS2)c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H23 mock treatment 43600.0 1430.0 0.08 44000.0 396.0 0.03 0.0798 0.9055 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 H24 mock treatment 38720.0 -3450.0 -0.2 41960.0 -1640.0 -0.12 -0.2293 -0.974 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I01 compound treatment 19960.0 -22200.0 -1.29 26560.0 -17000.0 -1.29 -1.8221 -1.0 1210543 TimTec1_005105 O=C(c1ccccc1)C2(OCCCCO2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I02 compound treatment 30480.0 -11700.0 -0.68 32000.0 -11600.0 -0.88 -1.0999 -0.9917 3212084 TimTec1_005106 CN1C(=O)/C(=C\NC(=O)C)/C(=C(C#N)C1=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I03 compound treatment 21080.0 -21100.0 -1.22 29440.0 -14200.0 -1.07 -1.6221 -0.9979 1253003 TimTec1_005107 COC(C)OC(=O)Cn1c(=O)sc2cccc(Cl)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I04 compound treatment 36440.0 -5730.0 -0.33 39800.0 -3800.0 -0.29 -0.4383 -0.9975 1054992 TimTec1_005108 Brc1ccc(C=C2C(=O)NC(=O)NC2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I05 compound treatment 640.0 -41500.0 -2.41 1160.0 -42400.0 -3.21 -3.9731 -0.9899 3212085 TimTec1_005109 Cc1ccccc1Nc2cc(C)c(C#N)c3nc4ccccc4n23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I06 compound treatment 13560.0 -28600.0 -1.66 23440.0 -20200.0 -1.53 -2.2513 -0.9992 1286333 TimTec1_005110 CCn1c2ccccc2c3cc(CN(C)Cc4ccccc4)ccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I07 compound treatment 31520.0 -10600.0 -0.62 41440.0 -2160.0 -0.16 -0.5521 -0.8649 1318051 TimTec1_005111 COc1ccc2OCc3ccccc3C(O)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I08 compound treatment 38040.0 -4130.0 -0.24 44680.0 1080.0 0.08 -0.1115 -0.4414 1348090 TimTec1_005112 CN(C)CCN(Cc1ccsc1)Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I09 compound treatment 35040.0 -7130.0 -0.41 42720.0 -884.0 -0.07 -0.3394 -0.8111 1334512 TimTec1_005113 COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C34CC5CC4CCC(C5)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I10 compound treatment 24880.0 -17300.0 -1.0 32280.0 -11300.0 -0.86 -1.3144 -0.997 1920628 TimTec1_005114 CN1/C(=C/C(=O)c2ccco2)/Sc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I11 compound treatment 25800.0 -16400.0 -0.95 28400.0 -15200.0 -1.15 -1.4844 -0.9954 3086180 TimTec1_005115 OC(=O)C(CC(=O)c1ccc(cc1)C2CCCCC2)NCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I12 compound treatment 15680.0 -26500.0 -1.53 22800.0 -20800.0 -1.57 -2.1987 -0.9999 3212145 TimTec1_005116 CCOc1ccc(cc1)c2n[nH]c(=S)[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I13 compound treatment 35920.0 -6250.0 -0.36 38720.0 -4880.0 -0.37 -0.5174 -0.9999 3086182 TimTec1_005117 O=C(Nn1cnnc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I14 compound treatment 43600.0 1430.0 0.08 43840.0 236.0 0.02 0.0713 0.8403 3212146 TimTec1_005118 CCOc1ccc(/C=C/C(=O)Sc2ccc(Cl)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I15 compound treatment 38480.0 -3690.0 -0.21 41960.0 -1640.0 -0.12 -0.2391 -0.9669 1487889 TimTec1_005119 OC(CNCN1C(=O)c2ccccc2C1=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I16 compound treatment 33200.0 -8970.0 -0.52 35480.0 -8120.0 -0.61 -0.8022 -0.9965 3212147 TimTec1_005120 Cc1cc(C)c(C#N)c(SCC=C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I17 compound treatment 35840.0 -6330.0 -0.37 39760.0 -3840.0 -0.29 -0.465 -0.9934 1921119 TimTec1_005121 CCNc1nc(OC(C(F)(F)F)C(F)(F)F)nc(n1)N(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I18 compound treatment 32000.0 -10200.0 -0.59 39600.0 -4000.0 -0.3 -0.6309 -0.9522 3086186 TimTec1_005122 CS/C(=N\C#N)/NC1CCCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I19 compound treatment 29280.0 -12900.0 -0.75 38200.0 -5400.0 -0.41 -0.8173 -0.9599 3212148 TimTec1_005123 O=C/1N(C2CCS(=O)(=O)C2)C(=S)S\C1=C/c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I20 compound treatment 23720.0 -18400.0 -1.07 25960.0 -17600.0 -1.34 -1.7002 -0.9939 1623935 TimTec1_005124 CCN(CC)c1ccc(N=C2C(=C(C#N)C#N)c3ccccc3C2=C(C#N)C#N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I21 compound treatment 32160.0 -10000.0 -0.58 34520.0 -9080.0 -0.69 -0.8962 -0.9964 3086189 TimTec1_005125 COCCN1C(=O)/C(=C\c2ccc3OCOc3c2)/SC1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I22 compound treatment 37760.0 -4410.0 -0.26 40000.0 -3600.0 -0.27 -0.3735 -0.9995 3212149 TimTec1_005126 COc1cc2CC[C@H](NC(=O)C(F)(F)F)c3cc(=O)c(O)ccc3-c2c(OC)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I23 mock treatment 44920.0 2750.0 0.16 46920.0 3320.0 0.25 0.2902 0.976 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 I24 mock treatment 32000.0 -10200.0 -0.59 47880.0 4280.0 0.32 -0.1877 -0.2792 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J01 compound treatment 28000.0 -14200.0 -0.82 29040.0 -14600.0 -1.1 -1.36 -0.9895 3086191 TimTec1_005127 CC(C)C1CCC(C)CC1OC(=O)CN2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J02 compound treatment 27800.0 -14400.0 -0.83 32360.0 -11200.0 -0.85 -1.1905 -0.9999 1218294 TimTec1_005128 CC(C)(C)C(=O)NC(=S)Nc1cccc(O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J03 compound treatment 2200.0 -40000.0 -2.32 2600.0 -41000.0 -3.1 -3.8321 -0.9896 1240106 TimTec1_005129 C(Nc1ncnc2sc3CCCCc3c12)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J04 compound treatment 32040.0 -10100.0 -0.59 36520.0 -7080.0 -0.54 -0.7941 -0.999 1554580 TimTec1_005130 Ic1ccccc1NC(=O)C2CN(C(=O)C2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J05 compound treatment 30200.0 -12000.0 -0.69 36600.0 -7000.0 -0.53 -0.8652 -0.9912 3212150 TimTec1_005131 OC(=O)C(Cc1c[nH]cn1)/N=C/c2cccc(CC=C)c2O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J06 compound treatment 7960.0 -34200.0 -1.98 10680.0 -32900.0 -2.49 -3.1637 -0.9936 1532567 TimTec1_005132 CCCOc1ccccc1C2NC(=S)NC(=C2C(=O)OC3CCCC(C)C3)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J07 compound treatment 33640.0 -8530.0 -0.49 44360.0 756.0 0.06 -0.3089 -0.621 3086259 TimTec1_005133 O=S(=O)(C1CCS(=O)(=O)C1)C2CCS(=O)(=O)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J08 compound treatment 27800.0 -14400.0 -0.83 30960.0 -12600.0 -0.96 -1.2654 -0.9976 1186821 TimTec1_005134 Cc1cc(C)c(NC(=O)C2CC3C4C=CC=CC4C2c5ccccc35)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J09 compound treatment 23040.0 -19100.0 -1.11 30600.0 -13000.0 -0.98 -1.4797 -0.9982 3212151 TimTec1_005135 COc1ccccc1C2C(C)C(C)(O)Oc3cc4OCOc4cc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J10 compound treatment 33520.0 -8650.0 -0.5 40800.0 -2800.0 -0.21 -0.5044 -0.9269 1139775 TimTec1_005136 Cc1cc(C(=O)O)c(CSc2ncn[nH]2)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J11 compound treatment 23320.0 -18800.0 -1.09 29920.0 -13700.0 -1.04 -1.5046 -0.9997 1141408 TimTec1_005137 Cc1ccccc1Cn2cnc3ccccc3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J12 compound treatment 32520.0 -9650.0 -0.56 36680.0 -6920.0 -0.52 -0.7659 -0.9995 1449011 TimTec1_005138 Cc1ccc(N2C(=O)CC(=O)N(C2=O)c3ccc(C)cc3C)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J13 compound treatment 30680.0 -11500.0 -0.67 34520.0 -9080.0 -0.69 -0.9569 -0.9999 1586155 TimTec1_005139 CC1=C(C(C(=C(C)N1)C(=O)Nc2ccccc2)c3ccccn3)C(=O)Nc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J14 compound treatment 13640.0 -28500.0 -1.65 19200.0 -24400.0 -1.85 -2.475 -0.9985 3086263 TimTec1_005140 CC(C)c1ccc(OCC(=O)Nc2ccccc2C(F)(F)F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J15 compound treatment 24920.0 -17200.0 -1.0 33720.0 -9880.0 -0.75 -1.2357 -0.9898 1332067 TimTec1_005141 CCOC(=O)c1c(C)oc(NC(=O)Nc2ccc(F)cc2)c1C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J16 compound treatment 3280.0 -38900.0 -2.25 3640.0 -40000.0 -3.03 -3.7322 -0.9895 1544744 TimTec1_005142 Cc1c(OCc2ccc(F)cc2)ccc3c4CCCCc4c(=O)oc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J17 compound treatment 17280.0 -24900.0 -1.44 20640.0 -23000.0 -1.74 -2.2488 -0.9957 1496408 TimTec1_005143 CCc1nnc(NC(=O)CC(=O)Nc2ccccc2C(=O)O)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J18 compound treatment 34960.0 -7210.0 -0.42 41520.0 -2080.0 -0.16 -0.4069 -0.9113 1851913 TimTec1_005144 CC(C)CC(N1C(=O)C2C(C3c4ccccc4C2c5ccccc35)C1=O)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J19 compound treatment 36840.0 -5330.0 -0.31 41280.0 -2320.0 -0.18 -0.3427 -0.9644 1716165 TimTec1_005145 NC(=O)c1sc(=S)n(c1N)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J20 compound treatment 35880.0 -6290.0 -0.36 37760.0 -5840.0 -0.44 -0.5704 -0.9954 3086267 TimTec1_005146 CC1SC(=NNC1=O)/N=C/c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J21 compound treatment 33640.0 -8530.0 -0.49 34920.0 -8680.0 -0.66 -0.8142 -0.9901 3212152 TimTec1_005147 OC(=O)C(CC(=O)c1ccc(Cl)cc1)N(Cc2ccccc2)Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J22 compound treatment 14160.0 -28000.0 -1.62 12680.0 -30900.0 -2.34 -2.8026 -0.984 3086269 TimTec1_005148 C=CCN1C(SC=C1c2ccccc2)/N=C/c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J23 mock treatment 39200.0 -2970.0 -0.17 41960.0 -1640.0 -0.12 -0.2096 -0.9874 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 J24 mock treatment 30040.0 -12100.0 -0.7 38400.0 -5200.0 -0.39 -0.7754 -0.9626 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K01 compound treatment 20320.0 -21800.0 -1.27 21480.0 -22100.0 -1.67 -2.0793 -0.9905 1023027 TimTec1_005149 Oc1ccccc1C(=O)CC(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K02 compound treatment 37120.0 -5050.0 -0.29 31280.0 -12300.0 -0.93 -0.8665 -0.8863 3212153 TimTec1_005150 OC[C@H]1O[C@@H](OCc2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K03 compound treatment 26480.0 -15700.0 -0.91 36360.0 -7240.0 -0.55 -1.0305 -0.9707 3086271 TimTec1_005151 CC(C)NC(=O)C[n+]1csc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K04 compound treatment 27200.0 -15000.0 -0.87 34600.0 -9000.0 -0.68 -1.0952 -0.9929 1118603 TimTec1_005152 CN1CCN(Cc2cc(Br)cs2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K05 compound treatment 22320.0 -19800.0 -1.15 25280.0 -18300.0 -1.39 -1.7939 -0.9957 3212154 TimTec1_005153 CC(O)c1cc(NC(=O)c2ccccc2)c(=O)oc1/C=C/N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K06 compound treatment 27160.0 -15000.0 -0.87 33760.0 -9840.0 -0.75 -1.1418 -0.997 3086274 TimTec1_005154 CN(Cc1ccccc1)Cc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K07 compound treatment 22480.0 -19700.0 -1.14 24680.0 -18900.0 -1.43 -1.8195 -0.9936 3212155 TimTec1_005155 O=C(/C=C/c1cccc(Oc2ccccc2)c1)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K08 compound treatment 30760.0 -11400.0 -0.66 33280.0 -10300.0 -0.78 -1.02 -0.9965 1586101 TimTec1_005156 CN(C)CCN(Cc1ccccc1)Cc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K09 compound treatment 32280.0 -9890.0 -0.57 30880.0 -12700.0 -0.96 -1.0861 -0.9692 1051443 TimTec1_005157 FC(F)(F)CN1C(=O)c2ccccc2C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K10 compound treatment 21320.0 -20800.0 -1.21 24760.0 -18800.0 -1.43 -1.8627 -0.9966 1698764 TimTec1_005158 COc1ccc(NCc2cn3ccccc3n2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K11 compound treatment 26320.0 -15800.0 -0.92 30120.0 -13500.0 -1.02 -1.371 -0.9986 3212156 TimTec1_005159 N#CCCN1CCCC2(CCCC2)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K12 compound treatment 19840.0 -22300.0 -1.29 22840.0 -20800.0 -1.57 -2.0261 -0.9953 3212157 TimTec1_005160 O=C/1N=C(S\C1=C/c2cccs2)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K13 compound treatment 22240.0 -19900.0 -1.15 29080.0 -14500.0 -1.1 -1.5938 -0.9997 1604720 TimTec1_005161 CCc1c(C)nc2ccccc2c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K14 compound treatment 28320.0 -13800.0 -0.8 27440.0 -16200.0 -1.22 -1.4325 -0.9791 3212158 TimTec1_005162 Cc1cc(C)cc(Nc2csc(N/C=N\O)n2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K15 compound treatment 26960.0 -15200.0 -0.88 32680.0 -10900.0 -0.83 -1.2078 -0.9995 3086348 TimTec1_005163 OC(=O)c1ccccc1NCn2nnc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K16 compound treatment 23880.0 -18300.0 -1.06 30080.0 -13500.0 -1.02 -1.4731 -0.9999 3212159 TimTec1_005164 Clc1ccc(cc1)C2=CC=C(C#N)C(N2)SCc3nc4ccccc4[nH]3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K17 compound treatment 27040.0 -15100.0 -0.88 30800.0 -12800.0 -0.97 -1.3051 -0.9987 1472272 TimTec1_005165 CNc1nc(nc(n1)N2CCOCC2)N(c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K18 compound treatment 27120.0 -15000.0 -0.87 32160.0 -11400.0 -0.87 -1.229 -1.0 3086351 TimTec1_005166 CCCC1CCC(CC1)c2ccc(cc2)/C(=N/O)/N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K19 compound treatment 19960.0 -22200.0 -1.29 33080.0 -10500.0 -0.8 -1.4731 -0.9734 3212160 TimTec1_005167 NS(=O)(=O)c1ccc(cc1)c2ccc(/C=C/3\SC(=S)N(Cc4ccccc4)C3=O)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K20 compound treatment 23480.0 -18700.0 -1.08 34840.0 -8760.0 -0.66 -1.2347 -0.9723 1130551 TimTec1_005168 COc1ccc(cc1)N(C(=O)c2ccco2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K21 compound treatment 32440.0 -9730.0 -0.56 29000.0 -14600.0 -1.11 -1.1802 -0.9511 3212161 TimTec1_005169 FC(F)(F)c1ccccc1NC(NC(=O)c2ccco2)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K22 compound treatment 32560.0 -9610.0 -0.56 30360.0 -13200.0 -1.0 -1.1025 -0.9615 1915266 TimTec1_005170 Cc1cc[n+](CCC(=O)O)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K23 mock treatment 30960.0 -11200.0 -0.65 35200.0 -8400.0 -0.64 -0.909 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 K24 mock treatment 36000.0 -6170.0 -0.36 31600.0 -12000.0 -0.91 -0.8952 -0.9169 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L01 compound treatment 31200.0 -11000.0 -0.64 33640.0 -9960.0 -0.75 -0.9827 -0.9964 1383984 TimTec1_005171 CCC1=CC(C)(CC)Nc2cc(C)ccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L02 compound treatment 29200.0 -13000.0 -0.75 30440.0 -13200.0 -1.0 -1.2359 -0.9903 1409216 TimTec1_005172 COc1cc(cc(OC)c1OC)C(=O)N(C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L03 compound treatment 32120.0 -10000.0 -0.58 43880.0 276.0 0.02 -0.3969 -0.6813 1273531 TimTec1_005173 OCC(O)C1OC(OCC1O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L04 compound treatment 26440.0 -15700.0 -0.91 34080.0 -9520.0 -0.72 -1.1541 -0.9933 1385587 TimTec1_005174 Cc1ccc(cc1)N2CC(CC2=O)C(=O)Nc3c(C)cccc3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L05 compound treatment 26800.0 -15400.0 -0.89 33960.0 -9640.0 -0.73 -1.1458 -0.9951 3212235 TimTec1_005175 OC(=O)C(Cc1ccc(O)cc1)/N=C/c2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L06 compound treatment 34000.0 -8170.0 -0.47 37120.0 -6480.0 -0.49 -0.6817 -0.9998 3086357 TimTec1_005176 COC(=O)c1c(NC(=O)C(F)(F)F)sc2CCCCc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L07 compound treatment 36080.0 -6090.0 -0.35 38240.0 -5360.0 -0.41 -0.5365 -0.9975 1333937 TimTec1_005177 O=S(=O)(C1CCS(=O)(=O)C1)N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L08 compound treatment 35720.0 -6450.0 -0.37 37840.0 -5760.0 -0.44 -0.5727 -0.997 1533793 TimTec1_005178 Cc1ccc(NC(=O)C2C(C=CC(C2C(=O)O)c3ccccc3)c4ccccc4)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L09 compound treatment 35640.0 -6530.0 -0.38 36640.0 -6960.0 -0.53 -0.6402 -0.9868 1611679 TimTec1_005179 COc1ccc(cc1)C(C2=C(O)CCCC2=O)c3cc4OCOc4cc3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L10 compound treatment 34560.0 -7610.0 -0.44 33160.0 -10400.0 -0.79 -0.8707 -0.962 1081231 TimTec1_005180 O=C1N(C(=O)c2nccnc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L11 compound treatment 24720.0 -17400.0 -1.01 27000.0 -16600.0 -1.26 -1.6035 -0.9942 1700569 TimTec1_005181 CCOC(=O)C1=C(O)c2ccccc2NC(=O)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L12 compound treatment 2320.0 -39800.0 -2.31 5480.0 -38100.0 -2.89 -3.6731 -0.9939 1371927 TimTec1_005182 Cc1cccc2c(cc(nc12)c3ccccc3)C(=O)NC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L13 compound treatment 2360.0 -39800.0 -2.31 3160.0 -40400.0 -3.06 -3.7956 -0.9903 3086362 TimTec1_005183 Cc1cc2ncc(nc2cc1C)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L14 compound treatment 36080.0 -6090.0 -0.35 33560.0 -10000.0 -0.76 -0.787 -0.939 1442595 TimTec1_005184 CC(C)C(N1C(=O)c2ccccc2C1=O)C(=O)Nc3ccc(I)cc3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L15 compound treatment 32560.0 -9610.0 -0.56 31760.0 -11800.0 -0.9 -1.0276 -0.9737 3086440 TimTec1_005185 CCOC(=O)/C(=C(/N)\c1cc2cccc(OC)c2oc1=O)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L16 compound treatment 34760.0 -7410.0 -0.43 33320.0 -10300.0 -0.78 -0.854 -0.9607 1612648 TimTec1_005186 CC1CCN(Cc2cc3c(cc(=O)oc3c(C)c2O)c4ccccc4)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L17 compound treatment 36480.0 -5690.0 -0.33 42360.0 -1240.0 -0.09 -0.2996 -0.8741 3212236 TimTec1_005187 Cn1cnnc1SCc2cccc(CSc3nncn3C)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L18 compound treatment 24200.0 -18000.0 -1.04 29840.0 -13800.0 -1.04 -1.4728 -1.0 3086444 TimTec1_005188 CCN(CC)c1ccc(/N=C/c2ccc3ccccc3n2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L19 compound treatment 22160.0 -20000.0 -1.16 23760.0 -19800.0 -1.5 -1.8818 -0.9918 1589064 TimTec1_005189 Clc1c(sc2ccccc12)C(=O)N3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L20 compound treatment 34440.0 -7730.0 -0.45 38840.0 -4760.0 -0.36 -0.5716 -0.9942 3212237 TimTec1_005190 CC1SC(=NNC1=O)/N=C/c2ccc(O)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L21 compound treatment 34680.0 -7490.0 -0.43 41760.0 -1840.0 -0.14 -0.4055 -0.8897 3086447 TimTec1_005191 CC(NC(CC(=O)c1ccc(F)cc1)C(=O)O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L22 compound treatment 28800.0 -13400.0 -0.77 27400.0 -16200.0 -1.23 -1.415 -0.9754 1451936 TimTec1_005192 CCCc1cc(=O)oc2cc(OCc3ccccc3)ccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L23 mock treatment 44440.0 2270.0 0.13 45280.0 1680.0 0.13 0.1828 0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 L24 mock treatment 42920.0 751.0 0.04 40840.0 -2760.0 -0.21 -0.1171 -0.5482 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M01 compound treatment 43080.0 911.0 0.05 44200.0 596.0 0.05 0.0692 0.997 3086449 TimTec1_005193 CCOC(=O)CN1CCN(CC1)C=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M02 compound treatment 17640.0 -24500.0 -1.42 18440.0 -25200.0 -1.9 -2.3518 -0.9896 3212238 TimTec1_005194 O=C(/C=C\Nc1cccc(N/C=C\C(=O)c2ccccc2)c1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M03 compound treatment 21440.0 -20700.0 -1.2 22440.0 -21200.0 -1.6 -1.982 -0.9899 1445055 TimTec1_005195 Cc1ccccc1OC(=O)Cn2c(=O)sc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M04 compound treatment 28600.0 -13600.0 -0.79 27160.0 -16400.0 -1.24 -1.436 -0.9754 1718720 TimTec1_005196 CN1CCN(Cc2coc3ccccc3c2=O)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M05 compound treatment 29400.0 -12800.0 -0.74 32680.0 -10900.0 -0.83 -1.1078 -0.9985 1415720 TimTec1_005197 OCC1Sc2ccccc2NC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M06 compound treatment 33280.0 -8890.0 -0.51 37520.0 -6080.0 -0.46 -0.6898 -0.9984 1643885 TimTec1_005198 NC(=O)C1CCN(Cc2ccc(Cl)cc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M07 compound treatment 22280.0 -19900.0 -1.15 23800.0 -19800.0 -1.5 -1.8748 -0.9916 3212239 TimTec1_005199 COc1ccc2c3CC[C@](C)(CCC(=O)O)C(=O)c3ccc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M08 compound treatment 29720.0 -12400.0 -0.72 34400.0 -9200.0 -0.7 -1.0026 -0.9998 3086453 TimTec1_005200 Cc1ccc(C(=O)Sc2nc(N)c(C#N)cc2C#N)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M09 compound treatment 24640.0 -17500.0 -1.02 25160.0 -18400.0 -1.4 -1.7053 -0.9878 1212803 TimTec1_005201 CCOc1ccc2c(cc(=O)oc2c1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M10 compound treatment 29320.0 -12800.0 -0.74 36520.0 -7080.0 -0.54 -0.9055 -0.987 3086455 TimTec1_005202 COc1ccc(cc1)c2cc(nc(=O)[nH]2)c3ccc(Br)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M11 compound treatment 33240.0 -8930.0 -0.52 33040.0 -10600.0 -0.8 -0.9312 -0.9778 1222652 TimTec1_005203 CCc1cc2OCCOc2cc1C(=O)c3ccc(I)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M12 compound treatment 28760.0 -13400.0 -0.78 28160.0 -15400.0 -1.17 -1.3759 -0.9803 1107292 TimTec1_005204 CCC1SC2=NCCN2C1(O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M13 compound treatment 22760.0 -19400.0 -1.12 20000.0 -23600.0 -1.79 -2.0585 -0.9751 1431781 TimTec1_005205 CC1(C)CC2(CCCN(CCC(O)(c3ccccc3)c4ccccc4)C2)CCO1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M14 compound treatment 25080.0 -17100.0 -0.99 28080.0 -15500.0 -1.18 -1.531 -0.9964 1622469 TimTec1_005206 CCCCn1c(nn(c1=O)S(=O)(=O)c2ccc(Br)cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M15 compound treatment 36920.0 -5250.0 -0.3 30360.0 -13200.0 -1.0 -0.9239 -0.8819 1265308 TimTec1_005207 OC(=O)c1ccccc1C(=O)Nc2cccc3ncccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M16 compound treatment 18920.0 -23200.0 -1.35 15600.0 -28000.0 -2.12 -2.4513 -0.976 3086459 TimTec1_005208 CSC1=Nc2ccccc2CN1c3ccc(Br)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M17 compound treatment 35960.0 -6210.0 -0.36 31600.0 -12000.0 -0.91 -0.8968 -0.9177 3086461 TimTec1_005209 O=C(Nc1nc[nH]n1)Nc2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M18 compound treatment 3720.0 -38400.0 -2.23 3160.0 -40400.0 -3.06 -3.7399 -0.9878 1609905 TimTec1_005210 CCCC1CCC(CC1)c2ccc(cc2)C(=O)CCN(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M19 compound treatment 37360.0 -4810.0 -0.28 35200.0 -8400.0 -0.64 -0.6468 -0.9314 3212240 TimTec1_005211 Cc1ccc(cc1)C(=O)N/C(=C\c2ccco2)/C(=O)N3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M20 compound treatment 39320.0 -2850.0 -0.17 39480.0 -4120.0 -0.31 -0.3374 -0.9556 3085449 TimTec1_005212 CC[C@@]1(C)N[C@@H](CS1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M21 compound treatment 44440.0 2270.0 0.13 43800.0 196.0 0.01 0.1036 0.782 1601693 TimTec1_005213 O=C(NC(Nc1cccc2ccccc12)C(=O)c3ccccc3)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M22 compound treatment 3400.0 -38800.0 -2.25 27800.0 -15800.0 -1.2 -2.4342 -0.9565 1269343 TimTec1_005214 CC(CC(=O)c1ccccc1)CC(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M23 mock treatment 41520.0 -649.0 -0.04 40040.0 -3560.0 -0.27 -0.2173 -0.7979 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 M24 mock treatment 34600.0 -7570.0 -0.44 38360.0 -5240.0 -0.4 -0.5907 -0.9988 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N01 compound treatment 40200.0 -1970.0 -0.11 38800.0 -4800.0 -0.36 -0.3378 -0.8863 3085453 TimTec1_005215 Cc1cc(C)c(CC2C(=O)c3ccccc3C2=O)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N02 compound treatment 31360.0 -10800.0 -0.63 25200.0 -18400.0 -1.39 -1.4279 -0.9349 1524336 TimTec1_005216 O=C(NCCc1nc2ccccc2[nH]1)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N03 compound treatment 30800.0 -11400.0 -0.66 28120.0 -15500.0 -1.17 -1.2945 -0.9629 1139245 TimTec1_005217 O=C(Cc1ccccc1)c2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N04 compound treatment 24000.0 -18200.0 -1.05 26120.0 -17500.0 -1.32 -1.6801 -0.9936 1718136 TimTec1_005218 O=c1oc2ccccc2cc1c3nnc(o3)c4cccc5ccccc45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N05 compound treatment 29440.0 -12700.0 -0.74 28320.0 -15300.0 -1.16 -1.3395 -0.9764 3085456 TimTec1_005219 CC1(C)CC(=O)C2C(=Nc3ccccc3N=C2c4ccccc4)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N06 compound treatment 16880.0 -25300.0 -1.47 18160.0 -25400.0 -1.93 -2.3979 -0.9909 1256766 TimTec1_005220 CC1N(c2cccc(C)c2)C3(CCCCC3)SC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N07 compound treatment 31440.0 -10700.0 -0.62 30000.0 -13600.0 -1.03 -1.1677 -0.9708 1496277 TimTec1_005221 NC(=O)C(C1CCS(=O)(=O)C1)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N08 compound treatment 30440.0 -11700.0 -0.68 33760.0 -9840.0 -0.75 -1.0074 -0.9989 1400156 TimTec1_005222 NNC(=O)C1CCCN1S(=O)(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N09 compound treatment 24160.0 -18000.0 -1.04 31400.0 -12200.0 -0.92 -1.391 -0.9982 1525056 TimTec1_005223 COc1ccc(cc1)C2C3C(=O)CCCC3(O)Oc4cc5OCOc5cc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N10 compound treatment 12920.0 -29200.0 -1.69 14760.0 -28800.0 -2.18 -2.7421 -0.9922 1231285 TimTec1_005224 CCN(CC)c1ccc2cc(c3ncc(o3)c4ccc(F)cc4)c(=O)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N11 compound treatment 35000.0 -7170.0 -0.42 34520.0 -9080.0 -0.69 -0.7799 -0.9709 3212241 TimTec1_005225 COc1cc2CCN(C)[C@H](Cc3ccc(O)cc3)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N12 compound treatment 26760.0 -15400.0 -0.89 21560.0 -22000.0 -1.67 -1.8111 -0.9571 1135918 TimTec1_005226 Oc1ccccc1C2=Nc3ncnn3C(C2)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N13 compound treatment 10000.0 -32200.0 -1.86 9520.0 -34100.0 -2.58 -3.1422 -0.9873 3212242 TimTec1_005227 CCC[n+]1ccc(cc1)c2c[nH]c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N14 compound treatment 30600.0 -11600.0 -0.67 27960.0 -15600.0 -1.18 -1.3113 -0.9637 1154608 TimTec1_005228 CC(C)c1ccc(OC(=O)C(C)N2C(=O)c3ccccc3C2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N15 compound treatment 37080.0 -5090.0 -0.29 34600.0 -9000.0 -0.68 -0.6904 -0.9297 3212243 TimTec1_005229 CCOC(=O)/C(=C(/N)\c1cc2cc(Br)cc(Br)c2oc1=O)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N16 compound treatment 26600.0 -15600.0 -0.9 25280.0 -18300.0 -1.39 -1.6186 -0.9783 1059298 TimTec1_005230 Cc1cc2oc(=O)c3CCCCc3c2c(O)c1CN4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N17 compound treatment 36680.0 -5490.0 -0.32 41440.0 -2160.0 -0.16 -0.3407 -0.9524 1365174 TimTec1_005231 NC(=O)CNC(=O)c1cccc(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N18 compound treatment 35320.0 -6850.0 -0.4 42680.0 -924.0 -0.07 -0.33 -0.8191 3085464 TimTec1_005232 CC(N1C(=O)CCC1=O)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N19 compound treatment 37360.0 -4810.0 -0.28 34320.0 -9280.0 -0.7 -0.6939 -0.9179 3212244 TimTec1_005233 COC(=O)c1cc(Br)ccc1OC(=O)/C=C/c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N20 compound treatment 28880.0 -13300.0 -0.77 35400.0 -8200.0 -0.62 -0.9835 -0.9943 3085466 TimTec1_005234 Oc1ccccc1/C=N/C2=NNC(=O)CS2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N21 compound treatment 40920.0 -1250.0 -0.07 32560.0 -11000.0 -0.84 -0.6423 -0.7654 3212245 TimTec1_005235 Cc1ccc(/C=C/C(=O)Nc2ccccc2C(F)(F)F)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N22 compound treatment 35280.0 -6890.0 -0.4 31080.0 -12500.0 -0.95 -0.9525 -0.9261 1411087 TimTec1_005236 CCOC(=O)Cc1cc(=O)oc2cc(OCC)ccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N23 mock treatment 31600.0 -10600.0 -0.61 38760.0 -4840.0 -0.37 -0.6922 -0.9699 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 N24 mock treatment 43360.0 1190.0 0.07 38440.0 -5160.0 -0.39 -0.2276 -0.5734 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O01 compound treatment 28400.0 -13800.0 -0.8 27080.0 -16500.0 -1.25 -1.4485 -0.9764 3212318 TimTec1_005237 C=CCOC(=O)OCn1c(=O)sc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O02 compound treatment 39760.0 -2410.0 -0.14 40800.0 -2800.0 -0.21 -0.2487 -0.9793 3212319 TimTec1_005238 CCCCN1N=C(C)CC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O03 compound treatment 25280.0 -16900.0 -0.98 23160.0 -20400.0 -1.55 -1.7861 -0.9756 3212320 TimTec1_005239 O=C(Cn1c(=O)sc2ccccc12)OC(C(=O)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O04 compound treatment 31280.0 -10900.0 -0.63 34360.0 -9240.0 -0.7 -0.9409 -0.9987 1379879 TimTec1_005240 CN1CCN(Cc2ccc(NC(=O)C)cc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O05 compound treatment 36400.0 -5770.0 -0.33 40680.0 -2920.0 -0.22 -0.3928 -0.98 1721138 TimTec1_005241 CC1CN(CC2COC(C)(C)O2)CC(C)O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O06 compound treatment 41920.0 -249.0 -0.01 40400.0 -3200.0 -0.24 -0.1817 -0.7478 1672440 TimTec1_005242 NC(=O)C1CCN(CC2CCC=CC2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O07 compound treatment 16200.0 -26000.0 -1.5 13160.0 -30400.0 -2.3 -2.6934 -0.9787 1624424 TimTec1_005243 COc1cc2c3CCc4cn[nH]c4-c3ccc2c(OC)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O08 compound treatment 37080.0 -5090.0 -0.29 40280.0 -3320.0 -0.25 -0.3864 -0.9969 1736587 TimTec1_005244 Fc1ccc(cc1)C(=O)Oc2ccccc2c3cnc4ccccc4n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O09 compound treatment 31520.0 -10600.0 -0.62 38720.0 -4880.0 -0.37 -0.6977 -0.97 1502476 TimTec1_005245 CC(C)C(NC(=O)OCc1ccccc1)C(=O)Oc2ccc3c(=O)c(Oc4ccccc4)coc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O10 compound treatment 34240.0 -7930.0 -0.46 37360.0 -6240.0 -0.47 -0.659 -0.9999 1214549 TimTec1_005246 COc1cc(ccc1O)C2CS(=O)(=O)CS(=O)(=O)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O11 compound treatment 30560.0 -11600.0 -0.67 39720.0 -3880.0 -0.29 -0.6835 -0.9311 1679192 TimTec1_005247 O=C(c1cccs1)c2ccc3OCCCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O12 compound treatment 35480.0 -6690.0 -0.39 41560.0 -2040.0 -0.15 -0.3834 -0.9189 3086118 TimTec1_005248 FC(F)(F)c1ccc2c(Cl)ccnc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O13 compound treatment 36160.0 -6010.0 -0.35 38680.0 -4920.0 -0.37 -0.5097 -0.9994 1449875 TimTec1_005249 CN(C)CCC(=O)c1ccc2OCCCOc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O14 compound treatment 37240.0 -4930.0 -0.29 38680.0 -4920.0 -0.37 -0.4655 -0.9914 3086120 TimTec1_005250 S=c1[nH]c(ccc1C#N)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O15 compound treatment 36800.0 -5370.0 -0.31 38560.0 -5040.0 -0.38 -0.4899 -0.9948 1687305 TimTec1_005251 O=C1N(C(=O)c2ccccc12)c3ccc4ncccc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O16 compound treatment 35920.0 -6250.0 -0.36 35120.0 -8480.0 -0.64 -0.7101 -0.9632 1675695 TimTec1_005252 CN1C2OC(=C(C#N)C(C2C(=O)N(C)C1=O)c3cccc(Br)c3)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O17 compound treatment 35280.0 -6890.0 -0.4 33400.0 -10200.0 -0.77 -0.8284 -0.9528 3086122 TimTec1_005253 O=C(/C=C/c1ccccc1)N2C(COC2=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O18 compound treatment 38200.0 -3970.0 -0.23 38640.0 -4960.0 -0.38 -0.4283 -0.9722 3212321 TimTec1_005254 CCN(CC)[P+](NC(=O)c1ccccc1)(N(CC)CC)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O19 compound treatment 34840.0 -7330.0 -0.42 37320.0 -6280.0 -0.48 -0.6366 -0.9984 3212322 TimTec1_005255 O=C(NC1CCCCC1)/C(=C/C=C\c2ccccc2)/NC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O20 compound treatment 42200.0 31.3 0.0 40960.0 -2640.0 -0.2 -0.1402 -0.7007 3086125 TimTec1_005256 O[C@@H]1CO[C@@H](Nc2ccccc2)[C@H](O)[C@H]1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O21 compound treatment 42080.0 -88.8 -0.01 40360.0 -3240.0 -0.25 -0.1773 -0.7218 1457665 TimTec1_005257 OP(=O)(c1nc2ccccc2n1CC=C)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O22 compound treatment 42360.0 191.0 0.01 38880.0 -4720.0 -0.36 -0.245 -0.6849 1597857 TimTec1_005258 OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O23 mock treatment 37440.0 -4730.0 -0.27 41560.0 -2040.0 -0.15 -0.3031 -0.9634 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 O24 mock treatment 36640.0 -5530.0 -0.32 27040.0 -16600.0 -1.25 -1.1131 -0.8601 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P01 compound treatment 44320.0 2150.0 0.12 38640.0 -4960.0 -0.38 -0.1775 -0.4485 3212323 TimTec1_005259 C[n+]1cn(NC(=O)c2ccc(cc2)C(=O)ON3C(=O)CCC3=O)cn1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P02 compound treatment 42160.0 -8.75 0.0 35040.0 -8560.0 -0.65 -0.4587 -0.7077 3212324 TimTec1_005260 OC(=O)C(Cc1ccccc1)NCc2c(O)ccc3c4CCCCc4c(=O)oc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P03 compound treatment 23240.0 -18900.0 -1.1 19560.0 -24000.0 -1.82 -2.0624 -0.9706 1665007 TimTec1_005261 COc1ccc(CCC(=O)c2ccc3OCCOc3c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P04 compound treatment 20480.0 -21700.0 -1.26 22560.0 -21000.0 -1.59 -2.0149 -0.9931 3212325 TimTec1_005262 Cc1nn(c2ccccc2)c3sc(cc13)C(=O)NN4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P05 compound treatment 25920.0 -16200.0 -0.94 28280.0 -15300.0 -1.16 -1.4859 -0.9946 3086129 TimTec1_005263 Oc1ccc(Cl)cc1/C=N/CCc2c[nH]c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P06 compound treatment 39720.0 -2450.0 -0.14 37200.0 -6400.0 -0.48 -0.4431 -0.8773 1176935 TimTec1_005264 CC(=O)Nc1cccc(NC(=O)N2CCOCC2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P07 compound treatment 32240.0 -9930.0 -0.58 34480.0 -9120.0 -0.69 -0.8951 -0.9959 3086130 TimTec1_005265 CN(N)P(=O)(c1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P08 compound treatment 39000.0 -3170.0 -0.18 37640.0 -5960.0 -0.45 -0.449 -0.9214 3212326 TimTec1_005266 OC(=O)c1ccccc1C(=O)Nc2ccc(/C=C/c3ccccc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P09 compound treatment 28560.0 -13600.0 -0.79 22320.0 -21300.0 -1.61 -1.6967 -0.946 1689960 TimTec1_005267 COc1ccc(cc1)C2C(C)C(C)(Oc3cc4OCOc4cc23)N5CCCC5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P10 compound treatment 30800.0 -11400.0 -0.66 28960.0 -14600.0 -1.11 -1.2495 -0.9691 3212327 TimTec1_005268 CC(C)c1ccc(cc1)C2C(=C(N)SC(=C2C#N)N)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P11 compound treatment 30560.0 -11600.0 -0.67 30160.0 -13400.0 -1.02 -1.1952 -0.9798 1088185 TimTec1_005269 COc1cc2C=CN(C(C#N)c2cc1OC)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P12 compound treatment 17520.0 -24600.0 -1.43 22960.0 -20600.0 -1.56 -2.1147 -0.999 1306739 TimTec1_005270 CC(C)CNc1ncnc2sc3CCCCc3c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P13 compound treatment 30120.0 -12000.0 -0.7 32800.0 -10800.0 -0.82 -1.0719 -0.9969 1251200 TimTec1_005271 O=C1CC(N2CCCc3ccccc23)C(=O)N1c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P14 compound treatment 18320.0 -23800.0 -1.38 18360.0 -25200.0 -1.91 -2.3282 -0.9873 1588848 TimTec1_005272 Cc1ccc(CNc2nc3n(C)c(=O)[nH]c(=O)c3n2Cc4ccccc4C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P15 compound treatment 29840.0 -12300.0 -0.71 32440.0 -11200.0 -0.85 -1.1026 -0.9965 1071878 TimTec1_005273 COc1ccc(cc1)n2c(=O)c3ccccc3[nH]c2=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P16 compound treatment 34000.0 -8170.0 -0.47 36040.0 -7560.0 -0.57 -0.7395 -0.9955 1718803 TimTec1_005274 Cc1cc(OC(=O)CNC(=O)OCc2ccccc2)cc3oc(=O)c4ccccc4c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P17 compound treatment 30880.0 -11300.0 -0.65 31920.0 -11700.0 -0.88 -1.0878 -0.989 1656249 TimTec1_005275 CCC(Cc1cccc(O)c1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P18 compound treatment 47160.0 4990.0 0.29 35280.0 -8320.0 -0.63 -0.241 -0.3477 1501431 TimTec1_005276 Brc1ccc(cc1)N2C(=O)CC(Nc3c[nH]c(=O)[nH]c3=O)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P19 compound treatment 36440.0 -5730.0 -0.33 36280.0 -7320.0 -0.55 -0.6267 -0.9699 3212328 TimTec1_005277 OC(=O)C(CC(=O)c1ccc(cc1)C2CCCCC2)NC3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P20 compound treatment 33560.0 -8610.0 -0.5 28200.0 -15400.0 -1.17 -1.1772 -0.9282 3086198 TimTec1_005278 Oc1ccccc1/C=N/C2=NNC(=CS2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P21 compound treatment 7400.0 -34800.0 -2.01 25480.0 -18100.0 -1.37 -2.3945 -0.9825 3086200 TimTec1_005279 N/C(=N\S(=O)(=O)c1ccc(Cl)cc1)/c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P22 compound treatment 39360.0 -2810.0 -0.16 31320.0 -12300.0 -0.93 -0.7725 -0.8184 1555180 TimTec1_005280 CC(NS(=O)(=O)c1ccc(C)cc1)C(=O)Oc2cc3oc(=O)c(Cl)c(C)c3cc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P23 mock treatment 38920.0 -3250.0 -0.19 35400.0 -8200.0 -0.62 -0.5722 -0.8818 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2077 P24 mock treatment 47920.0 5750.0 0.33 36160.0 -7440.0 -0.56 -0.1628 -0.2487 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A01 compound treatment 69080.0 3370.0 0.2 60720.0 3550.0 0.27 0.3279 0.9878 1179025 TimTec1_005281 Cc1c(OCC(=O)O)ccc2c(cc(=O)oc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A02 compound treatment 57360.0 -8350.0 -0.48 55840.0 -1330.0 -0.1 -0.4134 -0.8367 3212329 TimTec1_005282 C(=N/c1nccs1)\c2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A03 compound treatment 56320.0 -9390.0 -0.54 57640.0 466.0 0.04 -0.3597 -0.6598 1341807 TimTec1_005283 CCc1cc2c(=O)c(c3nc4ccccc4s3)c(C)oc2c(CN(C)C)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A04 compound treatment 36600.0 -29100.0 -1.69 31800.0 -25400.0 -1.92 -2.5506 -0.9979 3086205 TimTec1_005284 Cc1cc(C)c(C#N)c(SCC(=O)c2ccccc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A05 compound treatment 43240.0 -22500.0 -1.3 44320.0 -12900.0 -0.97 -1.6085 -0.9897 1015158 TimTec1_005285 COC(=O)c1ccc(NN)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A06 compound treatment 55800.0 -9910.0 -0.57 51240.0 -5930.0 -0.45 -0.7235 -0.9926 1579854 TimTec1_005286 Nc1nc(cs1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A07 compound treatment 39560.0 -26100.0 -1.51 40160.0 -17000.0 -1.29 -1.9819 -0.9967 3086207 TimTec1_005287 CC(C)c1cc(I)c(C)cc1OC(=O)NC(=O)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A08 compound treatment 52800.0 -12900.0 -0.75 53040.0 -4130.0 -0.31 -0.7501 -0.9252 1603281 TimTec1_005288 O=C(NCc1ccccc1)C2CCCN2C(=O)OCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A09 compound treatment 45880.0 -19800.0 -1.15 33200.0 -24000.0 -1.81 -2.0955 -0.9757 1494738 TimTec1_005289 O=C(Cn1c(=S)[nH]c2ccccc12)c3ccc(cc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A10 compound treatment 45600.0 -20100.0 -1.17 42000.0 -15200.0 -1.15 -1.636 -1.0 1405927 TimTec1_005290 Cc1cc(C)c(c(C)c1)S(=O)(=O)NCC2(OC3C=C2)C4C3C(=O)N(C4=O)c5ccc(Cl)cc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A11 compound treatment 62360.0 -3350.0 -0.19 52440.0 -4730.0 -0.36 -0.3906 -0.9585 1153776 TimTec1_005291 Cc1c(CCC(=O)NN)c(C)n2c3ccccc3nc2c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A12 compound treatment 64320.0 -1390.0 -0.08 45480.0 -11700.0 -0.89 -0.6828 -0.7682 3086211 TimTec1_005292 COc1cc(/C=N/Cc2ccco2)ccc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A13 compound treatment 59880.0 -5830.0 -0.34 50040.0 -7130.0 -0.54 -0.6206 -0.9745 1733511 TimTec1_005293 CC1(C)CC(CCO1)C(=O)COc2ccc3ccc(=O)oc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A14 compound treatment 63640.0 -2070.0 -0.12 47480.0 -9690.0 -0.73 -0.6036 -0.8119 1139337 TimTec1_005294 C(Oc1ccccc1OCc2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A15 compound treatment 52360.0 -13300.0 -0.77 38520.0 -18700.0 -1.41 -1.5453 -0.9599 3212403 TimTec1_005295 O=C(NC(SC1=NCCS1)C(=O)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A16 compound treatment 70080.0 4370.0 0.25 54120.0 -3050.0 -0.23 0.0156 0.0456 3086214 TimTec1_005296 CC(C)(CCN1CCOCC1)NC(=O)C=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A17 compound treatment 65480.0 -229.0 -0.01 49040.0 -8130.0 -0.62 -0.4447 -0.7222 1301247 TimTec1_005297 COc1cc2c(C(=O)O)c(C)oc2cc1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A18 compound treatment 50920.0 -14800.0 -0.86 42960.0 -14200.0 -1.08 -1.3666 -0.9936 1734603 TimTec1_005298 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C2c3ccoc3)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A19 compound treatment 56440.0 -9270.0 -0.54 51600.0 -5570.0 -0.42 -0.6781 -0.9929 3212404 TimTec1_005299 CN1CCc2[nH]c(=S)c(C#N)c(c3ccccc3)c2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A20 compound treatment 63760.0 -1950.0 -0.11 51640.0 -5530.0 -0.42 -0.376 -0.8668 3086280 TimTec1_005300 COC(=O)/C=C\1/Nc2ccccc2SC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A21 compound treatment 51400.0 -14300.0 -0.83 46760.0 -10400.0 -0.79 -1.1436 -0.9997 3212405 TimTec1_005301 Cc1cccc(NCN2C(=O)S/C(=C\c3cccc(F)c3)/C2=O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A22 compound treatment 65800.0 91.3 0.01 63160.0 5990.0 0.45 0.3241 0.7153 1421857 TimTec1_005302 COc1ccc(cc1OC)C(=O)Nc2nnc(o2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A23 mock treatment 68960.0 3250.0 0.19 64760.0 7590.0 0.57 0.5392 0.8923 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 A24 mock treatment 83200.0 17500.0 1.01 69920.0 12700.0 0.96 1.3988 0.9997 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B01 compound treatment 67640.0 1930.0 0.11 70480.0 13300.0 1.01 0.7913 0.7809 3212406 TimTec1_005303 CC(C)P(C(C)C)c1ccc(C#N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B02 compound treatment 57160.0 -8550.0 -0.5 53080.0 -4090.0 -0.31 -0.5693 -0.9745 3212407 TimTec1_005304 CC(C)COc1ccc(/C=C\2/S\C(=N/c3ccccc3)\N(N(C)C)C2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B03 compound treatment 67360.0 1650.0 0.1 58840.0 1670.0 0.13 0.1568 0.9907 1371685 TimTec1_005305 O=C(NCc1cccnc1)c2cc3ccccc3oc2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B04 compound treatment 56040.0 -9670.0 -0.56 49080.0 -8090.0 -0.61 -0.8293 -0.999 3086285 TimTec1_005306 COc1cc(OC)c(/C=N/c2ccccc2)cc1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B05 compound treatment 71280.0 5570.0 0.32 61600.0 4430.0 0.34 0.4652 0.9998 1138064 TimTec1_005307 OP(=O)(CCN1CCCC1=O)CN2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B06 compound treatment 62480.0 -3230.0 -0.19 53080.0 -4090.0 -0.31 -0.3514 -0.9708 1556230 TimTec1_005308 COc1ccc2CCC(C(=O)c2c1)C3(O)C(=O)Nc4ccccc43 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B07 compound treatment 55720.0 -9990.0 -0.58 45560.0 -11600.0 -0.88 -1.0308 -0.9794 3086287 TimTec1_005309 CCC(NC(=O)Oc1ccc2ccccc2c1)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B08 compound treatment 38760.0 -26900.0 -1.56 43640.0 -13500.0 -1.02 -1.8284 -0.9791 1141795 TimTec1_005310 CCC(Sc1nnc2c3ccccc3n(C)c2n1)C(=O)Nc4ccccc4C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B09 compound treatment 45480.0 -20200.0 -1.17 42960.0 -14200.0 -1.08 -1.5895 -0.9991 3086290 TimTec1_005311 Cc1ccc2cccc(SCc3ccc(Br)cc3)c2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B10 compound treatment 18760.0 -46900.0 -2.72 26880.0 -30300.0 -2.29 -3.5448 -0.9964 1716446 TimTec1_005312 Clc1cc(NC2CCCCC2)c3C(=O)c4ccccc4-c5onc1c53 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B11 compound treatment 38120.0 -27600.0 -1.6 35200.0 -22000.0 -1.66 -2.3064 -0.9998 3212408 TimTec1_005313 COc1cc(ccc1O)c2nc3ccccn3c2/N=C/c4cccc(Cl)c4Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B12 compound treatment 69920.0 4210.0 0.24 55960.0 -1210.0 -0.09 0.1076 0.4126 1140826 TimTec1_005314 OC1(CCN([C@@H]2CCCC[C@@H]21)C(=O)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B13 compound treatment 70640.0 4930.0 0.29 60640.0 3470.0 0.26 0.3876 0.9991 1456412 TimTec1_005315 CN(CP(=O)(O)CCc1ccccc1)C=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B14 compound treatment 63040.0 -2670.0 -0.15 59000.0 1830.0 0.14 -0.0116 -0.0559 1674110 TimTec1_005316 Cc1ccc(C)c(NC(=O)C2CC(O)CN2C(=O)OC(C)(C)C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B15 compound treatment 74880.0 9170.0 0.53 62720.0 5550.0 0.42 0.6726 0.9932 3212409 TimTec1_005317 CCN(CC)S(=O)(=O)c1ncn[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B16 compound treatment 43400.0 -22300.0 -1.29 41360.0 -15800.0 -1.2 -1.7604 -0.9993 3212410 TimTec1_005318 Oc1ccccc1/C=C\2/S\C(=N/c3ccccc3)\N(Cc4ccccc4)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B17 compound treatment 9960.0 -55700.0 -3.23 13040.0 -44100.0 -3.34 -4.6461 -0.9999 1238350 TimTec1_005319 CCN(CC)S(=O)(=O)c1cccc(c1)C(=O)Oc2cccc(c2)c3cnc4ccccc4n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B18 compound treatment 36160.0 -29500.0 -1.71 36280.0 -20900.0 -1.58 -2.3289 -0.9992 1373281 TimTec1_005320 OC(C#CC(O)(c1ccccc1)c2ccccc2)c3ccc(F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B19 compound treatment 64880.0 -829.0 -0.05 65920.0 8750.0 0.66 0.4342 0.6541 1306989 TimTec1_005321 COc1ccc2N(Cn3nc(c4ccccc4)n(c5ccccc5)c3=S)CCCc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B20 compound treatment 66320.0 611.0 0.04 63120.0 5950.0 0.45 0.3433 0.7604 1546728 TimTec1_005322 O=C(c1ccccc1)c2nc3ccccc3[nH]c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B21 compound treatment 13840.0 -51900.0 -3.01 14080.0 -43100.0 -3.26 -4.4315 -0.9992 3086367 TimTec1_005323 COC(=O)C1=C(C)N(/C(=C/c2cccc3ccccc23)/C1=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B22 compound treatment 50520.0 -15200.0 -0.88 46760.0 -10400.0 -0.79 -1.1796 -0.9985 3086369 TimTec1_005324 O=C(/C=C/c1ccco1)C2CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B23 mock treatment 72600.0 6890.0 0.4 62320.0 5150.0 0.39 0.5578 0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 B24 mock treatment 73080.0 7370.0 0.43 65480.0 8310.0 0.63 0.7466 0.9822 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C01 compound treatment 73040.0 7330.0 0.42 68040.0 10900.0 0.82 0.882 0.9527 1366978 TimTec1_005325 Cc1cc(=O)oc2cc(OC(=O)C3CCCN3C(=O)OC(C)(C)C)c(Cl)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C02 compound treatment 47480.0 -18200.0 -1.06 41120.0 -16100.0 -1.22 -1.6061 -0.9976 3086371 TimTec1_005326 NC1=C(C#N)C(c2ccccc2)c3ccc(N)cc3O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C03 compound treatment 61400.0 -4310.0 -0.25 51440.0 -5730.0 -0.43 -0.4834 -0.9655 1640630 TimTec1_005327 CCN(CC)Cc1c(O)ccc2cc(c3nc4ccccc4[nH]3)c(=O)oc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C04 compound treatment 38560.0 -27100.0 -1.57 38200.0 -19000.0 -1.44 -2.1278 -0.999 1378375 TimTec1_005328 O=C(Oc1ccccc1OC(=O)C2C3CCCCC23)C4C5CCCCC45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C05 compound treatment 63000.0 -2710.0 -0.16 53680.0 -3490.0 -0.26 -0.298 -0.969 1495247 TimTec1_005329 Brc1ccc(OCC(=O)Nc2ccccc2N3C(=O)c4ccccc4C3=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C06 compound treatment 40320.0 -25400.0 -1.47 39440.0 -17700.0 -1.34 -1.9893 -0.999 3212411 TimTec1_005330 C(=N/c1ccc2[nH]c(nc2c1)c3ccccc3)\c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C07 compound treatment 65480.0 -229.0 -0.01 58960.0 1790.0 0.14 0.0862 0.6348 3212412 TimTec1_005331 CCOC(=O)NC1(N/C(=N/c2ccccc2)/N3CCOCC3)Oc4ccccc4O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C08 compound treatment 45200.0 -20500.0 -1.19 42520.0 -14700.0 -1.11 -1.6245 -0.9994 1281134 TimTec1_005332 COc1ccccc1NC(=O)C2CC2(c3ccc(C)cc3)c4ccc(C)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C09 compound treatment 35880.0 -29800.0 -1.73 31680.0 -25500.0 -1.93 -2.5866 -0.9985 1467004 TimTec1_005333 Cc1cc(C)c(C(=O)Cn2c(=S)[nH]c3ccccc23)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C10 compound treatment 69760.0 4050.0 0.23 58840.0 1670.0 0.13 0.2552 0.9576 3086377 TimTec1_005334 COc1ccc(/C=N/CCN2Cc3ccccc3C2=O)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C11 compound treatment 39760.0 -25900.0 -1.5 36160.0 -21000.0 -1.59 -2.1878 -0.9996 1653534 TimTec1_005335 CCOC(=O)CCc1c(C)c(C#N)c2nc3ccccc3n2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C12 compound treatment 60720.0 -4990.0 -0.29 55120.0 -2050.0 -0.16 -0.3143 -0.9577 3086379 TimTec1_005336 Cc1cc(=O)oc2cc(OC(=O)/C=C/c3ccccc3)ccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C13 compound treatment 58200.0 -7510.0 -0.44 50880.0 -6290.0 -0.48 -0.6445 -0.999 3212413 TimTec1_005337 CC(C)NC(=O)n1cc(F)c(=O)[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C14 compound treatment 58320.0 -7390.0 -0.43 58240.0 1070.0 0.08 -0.2456 -0.5639 3086381 TimTec1_005338 CC(C)COc1ccccc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C15 compound treatment 54280.0 -11400.0 -0.66 49200.0 -7970.0 -0.6 -0.895 -0.9989 1498433 TimTec1_005339 O=C(NC(OCc1ccccc1)C(=O)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C16 compound treatment 40160.0 -25500.0 -1.48 37240.0 -19900.0 -1.51 -2.1136 -1.0 3212414 TimTec1_005340 CN(C(=O)C)c1ccc(/N=C\2/C(=O)Nc3ccc(C)c(Br)c23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C17 compound treatment 19800.0 -45900.0 -2.66 29880.0 -27300.0 -2.07 -3.3417 -0.9922 3086384 TimTec1_005341 C1Cc2c(C1)c3ccccc3n2c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C18 compound treatment 20120.0 -45600.0 -2.64 22160.0 -35000.0 -2.65 -3.7418 -1.0 1222403 TimTec1_005342 Nc1c(sc2snc(SCC(=O)c3ccccc3)c12)C(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C19 compound treatment 56320.0 -9390.0 -0.54 58960.0 1790.0 0.14 -0.289 -0.5157 3086386 TimTec1_005343 CC(C)(C)NC(=O)CSc1nc(N)c(C#N)cc1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C20 compound treatment 71720.0 6010.0 0.35 59640.0 2470.0 0.19 0.3783 0.9573 1290278 TimTec1_005344 COC(=O)C(CCCN1C(=O)c2ccccc2C1=O)(NC(=O)C)c3nn[nH]n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C21 compound treatment 28280.0 -37400.0 -2.17 28840.0 -28300.0 -2.14 -3.0499 -1.0 3086388 TimTec1_005345 COc1ccc(cc1)c2nc3cc(/N=C/c4cccc(OC)c4O)ccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C22 compound treatment 49920.0 -15800.0 -0.91 46600.0 -10600.0 -0.8 -1.2128 -0.9978 3212415 TimTec1_005346 COc1ccc(O)c(/C=N/c2cc(ccc2Oc3ccccc3)C(F)(F)F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C23 mock treatment 65040.0 -669.0 -0.04 62400.0 5230.0 0.4 0.2523 0.6348 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 C24 mock treatment 76760.0 11100.0 0.64 61160.0 3990.0 0.3 0.6661 0.9411 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D01 compound treatment 52120.0 -13600.0 -0.79 43160.0 -14000.0 -1.06 -1.3068 -0.9892 1377147 TimTec1_005347 CCC1=NN(C(=O)c2ccccc2F)C(O)(C1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D02 compound treatment 61120.0 -4590.0 -0.27 62280.0 5110.0 0.39 0.0853 0.1819 1581632 TimTec1_005348 OC(=O)CCC(=O)N(Cc1ccco1)C2CC(=O)N(C2=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D03 compound treatment 67840.0 2130.0 0.12 62120.0 4950.0 0.37 0.3521 0.893 1159067 TimTec1_005349 CC12C3CC(C=C3)C2C(=O)N(C1=O)c4cccc(c4)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D04 compound treatment 2400.0 -63300.0 -3.67 2680.0 -54500.0 -4.12 -5.5104 -0.9983 3086466 TimTec1_005350 OCCn/1c(cs\c1=N/c2ccccc2)c3ccc(cc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D05 compound treatment 8160.0 -57500.0 -3.33 16200.0 -41000.0 -3.1 -4.5507 -0.9993 1557266 TimTec1_005351 Clc1ccc(C(=O)Nc2ccc3nc(SCC(=O)N4CCOCC4)sc3c2)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D06 compound treatment 68600.0 2890.0 0.17 59160.0 1990.0 0.15 0.2248 0.9985 3212725 TimTec1_005352 OC(=O)c1ccc(cc1)N2C(=O)CC(SC(=N)N3N=C(CC3c4ccccc4)c5ccccc5)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D07 compound treatment 63120.0 -2590.0 -0.15 60000.0 2830.0 0.21 0.0452 0.1731 3086469 TimTec1_005353 O=C(CSc1ncn[nH]1)OCN2C(=O)c3ccccc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D08 compound treatment 43120.0 -22600.0 -1.31 37280.0 -19900.0 -1.51 -1.9902 -0.9976 3086470 TimTec1_005354 CCN(CC)c1ccc(/C=C\2/S/C(=N\c3cccc(C)c3)/NC2=O)c(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D09 compound treatment 68680.0 2970.0 0.17 56880.0 -294.0 -0.02 0.106 0.6107 1301370 TimTec1_005355 Cc1cc(C)cc(c1)N2C(Nc3ccccc3C2=O)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D10 compound treatment 74000.0 8290.0 0.48 61320.0 4150.0 0.31 0.5616 0.9787 3086472 TimTec1_005356 N/C(=C\C(=O)c1c(O)c(F)c(F)c(F)c1F)/C(=O)[O-] 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D11 compound treatment 49560.0 -16100.0 -0.94 37880.0 -19300.0 -1.46 -1.6943 -0.9768 1471806 TimTec1_005357 Fc1ccc(cc1)N2C(Nc3ccccc3C2=O)c4ccccc4Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D12 compound treatment 54160.0 -11500.0 -0.67 49880.0 -7290.0 -0.55 -0.8635 -0.9954 3212726 TimTec1_005358 CCCC1=C(C(C(=C(N)O1)C#N)c2ccccc2OC)C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D13 compound treatment 3200.0 -62500.0 -3.62 4480.0 -52700.0 -3.99 -5.3812 -0.9988 3086475 TimTec1_005359 Fc1ccc(/C=C/2\CN(Cc3ccccc3)C/C(=C/c4ccc(F)cc4)/C2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D14 compound treatment 68960.0 3250.0 0.19 65600.0 8430.0 0.64 0.5842 0.8784 3212727 TimTec1_005360 CN1C(=O)/C(=C\C=C\c2ccccc2Cl)/SC1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D15 compound treatment 30160.0 -35500.0 -2.06 30560.0 -26600.0 -2.01 -2.8808 -0.9999 1327468 TimTec1_005361 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3sc4CCCCCc4c3C#N)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D16 compound treatment 29120.0 -36600.0 -2.12 29720.0 -27500.0 -2.08 -2.9684 -1.0 1533582 TimTec1_005362 CCCn1c2ccccc2c3nnc(SCN4C(=O)c5ccccc5C4=O)nc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D17 compound treatment 49200.0 -16500.0 -0.96 43880.0 -13300.0 -1.01 -1.3879 -0.9997 1465950 TimTec1_005363 CCC(Sc1nnc2c3ccccc3n(C)c2n1)C(=O)Nc4ccc(cc4)S(=O)(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D18 compound treatment 69600.0 3890.0 0.23 59000.0 1830.0 0.14 0.2572 0.9724 1384915 TimTec1_005364 Clc1cccc(NC(=O)COC(=O)c2ccc(cc2)N3C(=O)CCC3=O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D19 compound treatment 64520.0 -1190.0 -0.07 56520.0 -654.0 -0.05 -0.0837 -0.9868 1450022 TimTec1_005365 COc1ccc2N(Cn3nc(COc4ccccc4)n(C)c3=S)CCCc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D20 compound treatment 66200.0 491.0 0.03 57080.0 -93.8 -0.01 0.0151 0.515 1291038 TimTec1_005366 CCC(O)C#CCN1CCN(C)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D21 compound treatment 38280.0 -27400.0 -1.59 40080.0 -17100.0 -1.29 -2.0386 -0.9948 1912707 TimTec1_005367 CC(C)(O)C(=O)/C=C/c1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D22 compound treatment 60080.0 -5630.0 -0.33 50200.0 -6970.0 -0.53 -0.6039 -0.9732 1025952 TimTec1_005368 Cc1cc(Cc2ccc(N)c(C)c2)ccc1N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D23 mock treatment 71320.0 5610.0 0.33 59120.0 1950.0 0.15 0.3341 0.9359 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 D24 mock treatment 69840.0 4130.0 0.24 62440.0 5270.0 0.4 0.4511 0.9702 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E01 compound treatment 68720.0 3010.0 0.17 56480.0 -694.0 -0.05 0.0862 0.4733 2102259 TimTec1_005369 CC(C)CC(NCc1c(O)ccc2c(C)cc(=O)oc12)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E02 compound treatment 65840.0 131.0 0.01 52760.0 -4410.0 -0.33 -0.2309 -0.6908 3086481 TimTec1_005370 O=C1NC(=O)/C(=C\c2ccccc2)/N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E03 compound treatment 63040.0 -2670.0 -0.15 53320.0 -3850.0 -0.29 -0.3156 -0.9559 1012035 TimTec1_005371 CN1CCC(O)(C(C1)C(=O)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E04 compound treatment 52840.0 -12900.0 -0.75 55960.0 -1210.0 -0.09 -0.5922 -0.7883 3212728 TimTec1_005372 CCc1ccc(cc1)C2C(=C(N)OC3=C2C(=O)CCC3)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E05 compound treatment 45560.0 -20100.0 -1.17 44240.0 -12900.0 -0.98 -1.5177 -0.9962 1629849 TimTec1_005373 CC(C)CN(CC(C)C)C(=O)CCN1C(=O)c2ccccc2C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E06 compound treatment 56920.0 -8790.0 -0.51 56240.0 -934.0 -0.07 -0.41 -0.7976 3212729 TimTec1_005374 CSc1nc2sc3COC(C)(C)Cc3c2c(=O)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E07 compound treatment 38200.0 -27500.0 -1.59 37400.0 -19800.0 -1.5 -2.1854 -0.9995 3212730 TimTec1_005375 CC(C)c1ccc(C)cc1OC(=O)NC2(Oc3ccc(Cl)cc3O2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E08 compound treatment 53840.0 -11900.0 -0.69 47360.0 -9810.0 -0.74 -1.0115 -0.9993 1308284 TimTec1_005376 Cc1ccc(cc1)N2CC(=O)SC32CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E09 compound treatment 67720.0 2010.0 0.12 54360.0 -2810.0 -0.21 -0.0682 -0.2809 3085473 TimTec1_005377 COc1ccc(cc1)C2=CN3C(=O)CSC3=NN2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E10 compound treatment 61200.0 -4510.0 -0.26 56320.0 -854.0 -0.06 -0.2304 -0.8562 1639246 TimTec1_005378 CCOC(=O)c1c(CN2CCOCC2)oc3ccc(OC)cc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E11 compound treatment 55560.0 -10100.0 -0.59 45200.0 -12000.0 -0.91 -1.0567 -0.9781 3085475 TimTec1_005379 CC(=C)Cn1c(S)nc2ccccc2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E12 compound treatment 52040.0 -13700.0 -0.79 45400.0 -11800.0 -0.89 -1.1902 -0.9983 3212731 TimTec1_005380 Cc1ccc(/C=C/2\OC(=O)C=C2)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E13 compound treatment 51520.0 -14200.0 -0.82 41920.0 -15300.0 -1.15 -1.3977 -0.9861 1303286 TimTec1_005381 CCc1cc2c(=O)c(coc2cc1O)c3nc(C)cs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E14 compound treatment 41440.0 -24300.0 -1.41 39680.0 -17500.0 -1.32 -1.9306 -0.9996 3085477 TimTec1_005382 O=C(CSc1nc(ccc1C#N)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E15 compound treatment 49080.0 -16600.0 -0.96 46240.0 -10900.0 -0.83 -1.2665 -0.9971 3212732 TimTec1_005383 COc1ccccc1N2CCN(CC2)/N=C/c3sccc3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E16 compound treatment 68240.0 2530.0 0.15 53840.0 -3330.0 -0.25 -0.0747 -0.2561 1527733 TimTec1_005384 Nc1nonc1C(=O)NCc2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E17 compound treatment 1040.0 -64700.0 -3.75 1240.0 -55900.0 -4.23 -5.6432 -0.9981 3212733 TimTec1_005385 O=C1N([C@H]2CC(=O)[C@@H]3OCC2O3)S(=O)(=O)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E18 compound treatment 23560.0 -42100.0 -2.44 22720.0 -34500.0 -2.61 -3.5709 -0.9995 1204206 TimTec1_005386 CC(C)(C)NC(=O)CSc1nsc(SCC(=O)NC(C)(C)C)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E19 compound treatment 49440.0 -16300.0 -0.94 46920.0 -10300.0 -0.78 -1.2153 -0.9953 3212734 TimTec1_005387 NC1=C(C#N)C(C(=c2s/c(=C\c3ccco3)/c(=O)n12)C#N)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E20 compound treatment 64840.0 -869.0 -0.05 60200.0 3030.0 0.23 0.1264 0.5389 1594563 TimTec1_005388 OC(=O)CCC(=O)Nc1ccccc1C#Cc2ccc(Br)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E21 compound treatment 28200.0 -37500.0 -2.17 44000.0 -13200.0 -1.0 -2.2418 -0.9376 3212735 TimTec1_005389 COc1cccc(/C=N/c2ccc(cc2)c3nc4ccc(C)cc4o3)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E22 compound treatment 47240.0 -18500.0 -1.07 41720.0 -15500.0 -1.17 -1.5838 -0.999 3085483 TimTec1_005390 C/C=C/c1c(C)nc2sc(C#N)c(N)c2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E23 mock treatment 69160.0 3450.0 0.2 54600.0 -2570.0 -0.19 0.0036 0.013 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 E24 mock treatment 66120.0 411.0 0.02 55720.0 -1450.0 -0.11 -0.061 -0.5415 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F01 compound treatment 40000.0 -25700.0 -1.49 37880.0 -19300.0 -1.46 -2.0859 -1.0 1199396 TimTec1_005391 O=C(NCc1cccs1)c2cccc(c2)S(=O)(=O)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F02 compound treatment 24640.0 -41100.0 -2.38 22800.0 -34400.0 -2.6 -3.5223 -0.999 1438185 TimTec1_005392 N#Cc1ccc(cc1C#N)n2c(nnc2c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F03 compound treatment 41120.0 -24600.0 -1.42 39960.0 -17200.0 -1.3 -1.9287 -0.999 1602974 TimTec1_005393 Cc1cc(C)c2oc(nc2c1)c3ccc(N)cc3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F04 compound treatment 71880.0 6170.0 0.36 58120.0 946.0 0.07 0.3035 0.8322 1565318 TimTec1_005394 COC(=O)C(C(Nc1ccccc1)c2ccccc2)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F05 compound treatment 53560.0 -12100.0 -0.7 51400.0 -5770.0 -0.44 -0.8067 -0.9737 3085487 TimTec1_005395 COC(=O)CSc1nc(C)nc2c3ccccc3oc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F06 compound treatment 68520.0 2810.0 0.16 51880.0 -5290.0 -0.4 -0.1682 -0.3888 3212736 TimTec1_005396 CN(C)c1ccc(/C=N/c2ccc3[nH]c(=O)[nH]c3c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F07 compound treatment 69360.0 3650.0 0.21 54480.0 -2690.0 -0.2 0.0054 0.0184 3085489 TimTec1_005397 CN(C)C(=O)/C(=C/c1ccc(F)cc1)/NC(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F08 compound treatment 52240.0 -13500.0 -0.78 55680.0 -1490.0 -0.11 -0.6317 -0.8012 3212737 TimTec1_005398 N#Cc1c(NCSCc2ccccc2)sc3CCCCCc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F09 compound treatment 52560.0 -13100.0 -0.76 45960.0 -11200.0 -0.85 -1.1389 -0.9985 1212031 TimTec1_005399 CC(C)(C)C(=O)Nc1cc(NC(=O)C(C)(C)C)cc(c1)C(=O)Nc2ccc(Oc3ccccc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F10 compound treatment 66200.0 491.0 0.03 57560.0 386.0 0.03 0.0408 0.9999 1476455 TimTec1_005400 CC(CS(=O)(=O)c1ccccc1)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F11 compound treatment 63640.0 -2070.0 -0.12 55120.0 -2050.0 -0.16 -0.1947 -0.9917 1295263 TimTec1_005401 Cc1ccc(cc1)S(=O)(=O)Nc2ccc(cc2)c3nc4ccccc4o3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F12 compound treatment 66480.0 771.0 0.04 57280.0 106.0 0.01 0.0373 0.8212 1158028 TimTec1_005402 C(Sc1nnc2c3ccccc3n(Cc4ccccc4)c2n1)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F13 compound treatment 76360.0 10700.0 0.62 62640.0 5470.0 0.41 0.7289 0.9811 3086060 TimTec1_005403 CCC(NC(=O)OC1CCCCC1C)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F14 compound treatment 3280.0 -62400.0 -3.62 5600.0 -51600.0 -3.9 -5.318 -0.9993 3212738 TimTec1_005404 CN1C(=O)S/C(=C/c2cc(C)n(c2C)c3ccccc3)/C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F15 compound treatment 2320.0 -63400.0 -3.67 6320.0 -50900.0 -3.85 -5.3188 -0.9997 1322720 TimTec1_005405 CCOC(=O)c1c(CSc2ccccc2)oc3ccc(O)c(CN(C)C)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F16 compound treatment 66800.0 1090.0 0.06 49840.0 -7330.0 -0.56 -0.3478 -0.6225 1183235 TimTec1_005406 Cc1ccc2nc(NC(=O)C(Cc3ccccc3)NC(=O)OCc4ccccc4)sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F17 compound treatment 62920.0 -2790.0 -0.16 55760.0 -1410.0 -0.11 -0.1899 -0.98 1662436 TimTec1_005407 Nc1nonc1n2nnc(C(=O)N3CCCC3)c2c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F18 compound treatment 68600.0 2890.0 0.17 61880.0 4710.0 0.36 0.3703 0.9408 1606341 TimTec1_005408 COC(=O)C1=C(c2ccccc2)S(=O)(=O)CCN1C(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F19 compound treatment 54320.0 -11400.0 -0.66 45320.0 -11900.0 -0.9 -1.101 -0.9886 1282067 TimTec1_005409 COC(=O)c1ccc(NC(=O)CSc2nnc(N)s2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F20 compound treatment 30600.0 -35100.0 -2.03 31600.0 -25600.0 -1.94 -2.8071 -0.9997 3086064 TimTec1_005410 CSC1=NC(C)(C)Cc2c(C)cccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F21 compound treatment 63600.0 -2110.0 -0.12 54080.0 -3090.0 -0.23 -0.252 -0.954 1037267 TimTec1_005411 CC(=O)Nc1ccc(cc1)S(=O)(=O)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F22 compound treatment 32520.0 -33200.0 -1.92 31640.0 -25500.0 -1.93 -2.7263 -1.0 1160915 TimTec1_005412 Cc1cccc(c1C)n2c(CSc3nc4ccccc4[nH]3)nc5ccccc5c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F23 mock treatment 76200.0 10500.0 0.61 62400.0 5230.0 0.4 0.7095 0.9784 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 F24 mock treatment 65400.0 -309.0 -0.02 66520.0 9350.0 0.71 0.4876 0.689 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G01 compound treatment 75920.0 10200.0 0.59 56400.0 -774.0 -0.06 0.3769 0.634 3086066 TimTec1_005413 CCC(C)C(NCc1c(O)ccc2c(C)cc(=O)oc12)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G02 compound treatment 61120.0 -4590.0 -0.27 50880.0 -6290.0 -0.48 -0.5249 -0.962 3212809 TimTec1_005414 COC(=O)n1c(SC)nc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G03 compound treatment 66240.0 531.0 0.03 57120.0 -53.8 0.0 0.0189 0.6083 1428822 TimTec1_005415 CC(C)c1ccccc1NC(=O)CN2C(=O)c3ccccc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G04 compound treatment 62480.0 -3230.0 -0.19 50800.0 -6370.0 -0.48 -0.4734 -0.9149 1673731 TimTec1_005416 C=CCN(CC=C)C(=S)Oc1ccc(cc1)C(=O)Nc2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G05 compound treatment 71760.0 6050.0 0.35 57960.0 786.0 0.06 0.29 0.8155 3212810 TimTec1_005417 NNC(=O)c1cc(nn1c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G06 compound treatment 57400.0 -8310.0 -0.48 48640.0 -8530.0 -0.65 -0.7972 -0.9895 3086070 TimTec1_005418 COC(=O)Nc1ccc(Br)cn1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G07 compound treatment 69600.0 3890.0 0.23 54040.0 -3130.0 -0.24 -0.0083 -0.0254 3212811 TimTec1_005419 CN/1N(C(=NC(=O)\C1=C/c2ccc(O)cc2)C)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G08 compound treatment 20480.0 -45200.0 -2.62 15680.0 -41500.0 -3.14 -4.0738 -0.9959 1496851 TimTec1_005420 CCSc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G09 compound treatment 67800.0 2090.0 0.12 54880.0 -2290.0 -0.17 -0.0371 -0.1752 3212812 TimTec1_005421 CC1SC2=NNC(=CN2C1=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G10 compound treatment 73640.0 7930.0 0.46 59440.0 2270.0 0.17 0.4462 0.9098 1578108 TimTec1_005422 CC(=O)Oc1ccc(cc1)c2nc3ccccc3c(=O)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G11 compound treatment 59480.0 -6230.0 -0.36 54640.0 -2530.0 -0.19 -0.3908 -0.9562 1637150 TimTec1_005423 Cc1ccc(cc1)S(=O)(=O)NCCC(=O)Oc2cc3oc(=O)c4CCCCc4c3cc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G12 compound treatment 19080.0 -46600.0 -2.7 21120.0 -36100.0 -2.73 -3.84 -1.0 1014256 TimTec1_005424 c1c([nH]c2ccccc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G13 compound treatment 11440.0 -54300.0 -3.14 12960.0 -44200.0 -3.35 -4.5898 -0.9995 1442327 TimTec1_005425 CCc1cc(C(=O)Cc2nc(C)cs2)c(O)cc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G14 compound treatment 60200.0 -5510.0 -0.32 53160.0 -4010.0 -0.3 -0.4405 -0.9997 3212813 TimTec1_005426 CCOc1cc(/C=N/CCN2Cc3ccccc3C2=O)ccc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G15 compound treatment 64000.0 -1710.0 -0.1 53440.0 -3730.0 -0.28 -0.2698 -0.9011 3086140 TimTec1_005427 COc1ccc(/C=N/S(=O)(=O)c2ccccc2)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G16 compound treatment 66360.0 651.0 0.04 53280.0 -3890.0 -0.29 -0.1817 -0.6116 3212814 TimTec1_005428 Clc1ccc(NC(=O)CSC(=O)c2ccccc2)nc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G17 compound treatment 46240.0 -19500.0 -1.13 36560.0 -20600.0 -1.56 -1.9009 -0.9873 3086142 TimTec1_005429 Oc1n[n+](no1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G18 compound treatment 62040.0 -3670.0 -0.21 46720.0 -10500.0 -0.79 -0.7098 -0.8663 3212815 TimTec1_005430 COc1cc(/C=N/c2oc(C)c(C)c2C#N)cc(Br)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G19 compound treatment 62920.0 -2790.0 -0.16 56160.0 -1010.0 -0.08 -0.1685 -0.9421 1400147 TimTec1_005431 Cc1ccccc1OCC(=O)Nc2cc(Sc3ccccn3)cc(c2)S(=O)(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G20 compound treatment 70400.0 4690.0 0.27 58560.0 1390.0 0.1 0.2664 0.9143 3086144 TimTec1_005432 C(=N/c1nnc2[nH]cnn12)\c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G21 compound treatment 46840.0 -18900.0 -1.09 39400.0 -17800.0 -1.35 -1.7243 -0.9947 1704603 TimTec1_005433 CCN(CC)C(=O)N1CCc2ccccc2C1CN3C(=O)c4ccccc4C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G22 compound treatment 72440.0 6730.0 0.39 61120.0 3950.0 0.3 0.487 0.9913 3212816 TimTec1_005434 CCc1c(C)[nH]c(=S)c(C#N)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G23 mock treatment 62640.0 -3070.0 -0.18 58880.0 1710.0 0.13 -0.0344 -0.1565 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 G24 mock treatment 69000.0 3290.0 0.19 55680.0 -1490.0 -0.11 0.0549 0.2476 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H01 compound treatment 57800.0 -7910.0 -0.46 55560.0 -1610.0 -0.12 -0.4104 -0.8654 1451425 TimTec1_005435 CCN(CC)S(=O)(=O)c1cccc(c1)C(=O)Nc2nncs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H02 compound treatment 52920.0 -12800.0 -0.74 52280.0 -4890.0 -0.37 -0.7859 -0.9487 3086147 TimTec1_005436 COc1cc(/C=C\2/S\C(=N/c3ccccc3)\N(N(C)C)C2=O)cc(Br)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H03 compound treatment 63920.0 -1790.0 -0.1 54000.0 -3170.0 -0.24 -0.2432 -0.9294 3212817 TimTec1_005437 Cc1cc-2c(cn1)/C(=N\c3ccccc3C)/c4ccccc42 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H04 compound treatment 36160.0 -29500.0 -1.71 33960.0 -23200.0 -1.76 -2.453 -0.9999 3086149 TimTec1_005438 Clc1ss/c(=N\c2ccccn2)/c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H05 compound treatment 54360.0 -11300.0 -0.66 44920.0 -12300.0 -0.93 -1.1208 -0.9858 1471924 TimTec1_005439 COC(=O)c1ccc2c(c1)sc3nc(cn32)c4ccc(OC)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H06 compound treatment 46480.0 -19200.0 -1.11 36720.0 -20500.0 -1.55 -1.8825 -0.987 3212818 TimTec1_005440 Cc1ccc(/N=C/c2ccc3OCOc3c2)c(Br)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H07 compound treatment 63480.0 -2230.0 -0.13 54240.0 -2930.0 -0.22 -0.2483 -0.9667 1713930 TimTec1_005441 CC(C)C(O)(C#CCN1CCCCC1)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H08 compound treatment 63240.0 -2470.0 -0.14 49640.0 -7530.0 -0.57 -0.5044 -0.8579 3212819 TimTec1_005442 CC(=O)NC1=NC(=O)/C(=C\c2ccc(Cl)cc2)/S1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H09 compound treatment 64360.0 -1350.0 -0.08 53360.0 -3810.0 -0.29 -0.2594 -0.8673 1216409 TimTec1_005443 Nc1nnc(SCC(=O)NCc2ccco2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H10 compound treatment 30000.0 -35700.0 -2.07 32440.0 -24700.0 -1.87 -2.7868 -0.9988 3212820 TimTec1_005444 Cc1nc(Sc2ccccc2)c3oc4ccccc4c3n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H11 compound treatment 51320.0 -14400.0 -0.83 45840.0 -11300.0 -0.86 -1.1961 -0.9999 1240888 TimTec1_005445 O=C1CSC2(CCCCC2)N1Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H12 compound treatment 53880.0 -11800.0 -0.69 43760.0 -13400.0 -1.02 -1.2026 -0.9817 3212821 TimTec1_005446 Clc1ccc(NC(=O)CSC2=NCCS2)nc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H13 compound treatment 49800.0 -15900.0 -0.92 38160.0 -19000.0 -1.44 -1.6694 -0.9768 3212822 TimTec1_005447 COC(=O)C1=C(N)N(C2=C(C1c3ccccc3)C(=O)CCC2)c4cccc(c4)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H14 compound treatment 52560.0 -13100.0 -0.76 46680.0 -10500.0 -0.79 -1.1003 -0.9998 1666111 TimTec1_005448 Oc1ccccc1N=c2c(=O)c3ccccc3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H15 compound treatment 51000.0 -14700.0 -0.85 48960.0 -8210.0 -0.62 -1.0422 -0.988 3086218 TimTec1_005449 O=C(NC1CC1)/C=C/c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H16 compound treatment 52840.0 -12900.0 -0.75 49040.0 -8130.0 -0.62 -0.9626 -0.9955 1687122 TimTec1_005450 COc1ccc(cc1)C2CC3(OCCO3)C4(CCCCC4)O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H17 compound treatment 55240.0 -10500.0 -0.61 44760.0 -12400.0 -0.94 -1.0933 -0.9776 3212823 TimTec1_005451 Clc1cccc(/C=C\2/SC(=NC2=O)N3CCCC3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H18 compound treatment 25040.0 -40700.0 -2.36 22040.0 -35100.0 -2.66 -3.5466 -0.9982 1549014 TimTec1_005452 O=C(CSc1nnc2c3ccccc3[nH]c2n1)NCc4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H19 compound treatment 51320.0 -14400.0 -0.83 47840.0 -9330.0 -0.71 -1.0891 -0.9966 1530955 TimTec1_005453 COC(=O)C1=C(N)N(C2=C(C1c3ccccc3)C(=O)CC(C)(C)C2)c4ccc(F)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H20 compound treatment 68680.0 2970.0 0.17 52600.0 -4570.0 -0.35 -0.1231 -0.3183 1138726 TimTec1_005454 CCOC(=O)c1ccccc1NCn2c(=S)oc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H21 compound treatment 63280.0 -2430.0 -0.14 62280.0 5110.0 0.39 0.1738 0.4225 1258567 TimTec1_005455 OC(=O)c1ccc2C(=O)N(C(=O)c2c1)c3cccc(c3)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H22 compound treatment 69560.0 3850.0 0.22 54280.0 -2890.0 -0.22 0.0029 0.0093 1345011 TimTec1_005456 OC(=O)c1ccccc1NC(=O)c2cc(ccc2Cl)S(=O)(=O)N3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H23 mock treatment 74800.0 9090.0 0.53 62880.0 5710.0 0.43 0.6779 0.9951 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 H24 mock treatment 56480.0 -9230.0 -0.53 57880.0 706.0 0.05 -0.3403 -0.6333 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I01 compound treatment 46840.0 -18900.0 -1.09 43800.0 -13400.0 -1.01 -1.4888 -0.9993 1452955 TimTec1_005457 CCOC(=O)c1c(oc2ccc(OCC)cc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I02 compound treatment 46200.0 -19500.0 -1.13 45840.0 -11300.0 -0.86 -1.4059 -0.9907 1419694 TimTec1_005458 CCCc1ccc2c(N)c(sc2n1)C(=O)c3ccc(Br)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I03 compound treatment 62720.0 -2990.0 -0.17 55960.0 -1210.0 -0.09 -0.1874 -0.956 1348330 TimTec1_005459 CCc1ccc(OC(=O)CN2C(=O)c3ccccc3C2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I04 compound treatment 54640.0 -11100.0 -0.64 47080.0 -10100.0 -0.76 -0.9937 -0.9962 1011570 TimTec1_005460 COc1ccc2oc(=O)cc(C)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I05 compound treatment 55360.0 -10300.0 -0.6 51000.0 -6170.0 -0.47 -0.7544 -0.9924 1591902 TimTec1_005461 NNC(=O)Cc1nc2ccccc2[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I06 compound treatment 81520.0 15800.0 0.92 69960.0 12800.0 0.97 1.3321 0.9996 3086226 TimTec1_005462 CCCC(=O)n1c(=S)oc2cc(Cl)ccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I07 compound treatment 64040.0 -1670.0 -0.1 57000.0 -174.0 -0.01 -0.0777 -0.796 3212824 TimTec1_005463 Cc1ccc(cc1)C(=O)/N=c\2/n(C)n(c(C)nc2=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I08 compound treatment 60040.0 -5670.0 -0.33 55960.0 -1210.0 -0.09 -0.2972 -0.8715 1332287 TimTec1_005464 NC(=O)CN(c1ccc(Cl)cc1Cl)S(=O)(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I09 compound treatment 48800.0 -16900.0 -0.98 43760.0 -13400.0 -1.02 -1.4107 -0.9998 1228160 TimTec1_005465 O=C(SCc1nc2ccccc2[nH]1)c3ccc(cc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I10 compound treatment 44160.0 -21500.0 -1.25 42000.0 -15200.0 -1.15 -1.695 -0.9991 3212825 TimTec1_005466 Cc1ccc2cc3/C(=N\C4CCCCC4)/c5ccccc5-c3nc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I11 compound treatment 61800.0 -3910.0 -0.23 52000.0 -5170.0 -0.39 -0.4371 -0.9661 3086229 TimTec1_005467 Cc1ccc2nc(NCc3ccccc3)c(/C=N/c4ccc(Cl)cc4)c(=O)n2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I12 compound treatment 56920.0 -8790.0 -0.51 48240.0 -8930.0 -0.68 -0.8382 -0.9902 3212826 TimTec1_005468 COc1ccc(/N=C\2/c3ccccc3-c4nc5ccccc5nc24)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I13 compound treatment 47080.0 -18600.0 -1.08 39200.0 -18000.0 -1.36 -1.7252 -0.9934 1582817 TimTec1_005469 CN(C)Cc1c(C)cc2oc(=O)c3CCCCc3c2c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I14 compound treatment 66400.0 691.0 0.04 63200.0 6030.0 0.46 0.3509 0.7662 3086232 TimTec1_005470 CCc1ccc(cc1)c2nn(c3ccccc3)c(=S)c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I15 compound treatment 60840.0 -4870.0 -0.28 55400.0 -1770.0 -0.13 -0.2944 -0.9424 3212903 TimTec1_005471 CN(C)c1ccc(/C=N/S(=O)(=O)c2ccccc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I16 compound treatment 64840.0 -869.0 -0.05 61400.0 4230.0 0.32 0.1906 0.5886 1444311 TimTec1_005472 COC(=O)c1ccc(OC(=O)COC(=O)CN2C(=O)c3ccccc3C2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I17 compound treatment 45880.0 -19800.0 -1.15 39720.0 -17500.0 -1.32 -1.7465 -0.9976 3212904 TimTec1_005473 CSc1c(CC(=O)Nc2ccccc2)n(Cc3ccccc3)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I18 compound treatment 66120.0 411.0 0.02 51560.0 -5610.0 -0.42 -0.2836 -0.6664 3086235 TimTec1_005474 Fc1ccc(/C=N/c2nnc3[nH]cnn23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I19 compound treatment 560.0 -65100.0 -3.77 560.0 -56600.0 -4.29 -5.6992 -0.998 3212905 TimTec1_005475 CC(C)(C)c1ccc(cc1)c2nc3ccccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I20 compound treatment 65280.0 -429.0 -0.02 62760.0 5590.0 0.42 0.2814 0.6644 3086300 TimTec1_005476 CCC1(C)OC(=O)N(C1=C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I21 compound treatment 50120.0 -15600.0 -0.9 42200.0 -15000.0 -1.13 -1.4401 -0.9937 3086302 TimTec1_005477 COCc1cc(C)nc2snc(Br)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I22 compound treatment 65800.0 91.3 0.01 54360.0 -2810.0 -0.21 -0.1469 -0.6893 3212906 TimTec1_005478 Cc1cc(C)c2c(N)c(sc2n1)C(=O)OC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I23 mock treatment 66560.0 851.0 0.05 56120.0 -1050.0 -0.08 -0.0215 -0.2295 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 I24 mock treatment 63360.0 -2350.0 -0.14 56560.0 -614.0 -0.05 -0.1291 -0.8976 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J01 compound treatment 40840.0 -24900.0 -1.44 35560.0 -21600.0 -1.64 -2.1757 -0.998 1654696 TimTec1_005479 CC(C)C1N(CCN1S(=O)(=O)c2ccc(C)cc2)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J02 compound treatment 55840.0 -9870.0 -0.57 44440.0 -12700.0 -0.96 -1.0859 -0.9689 3086304 TimTec1_005480 FC(F)(F)COc1nc(nc(n1)N2CCN(CC2)c3ccccc3)N4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J03 compound treatment 58760.0 -6950.0 -0.4 48080.0 -9090.0 -0.69 -0.7714 -0.9674 1724083 TimTec1_005481 NC1=C(C#N)C(C2=C(CCCC2=O)N1c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J04 compound treatment 45640.0 -20100.0 -1.16 43080.0 -14100.0 -1.07 -1.5765 -0.9991 3086306 TimTec1_005482 CCCCc1c(C)c2ccc(OCC=C)cc2oc1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J05 compound treatment 1720.0 -64000.0 -3.71 640.0 -56500.0 -4.28 -5.6474 -0.9974 3212907 TimTec1_005483 COC(=O)CSC1=NC(=O)/C(=C/c2ccc(OC)cc2)/S1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J06 compound treatment 25680.0 -40000.0 -2.32 20760.0 -36400.0 -2.76 -3.5889 -0.9963 3086308 TimTec1_005484 Brc1cc2OCOc2cc1/C=N/c3c(nc4ccccn34)c5ccco5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J07 compound treatment 53480.0 -12200.0 -0.71 48960.0 -8210.0 -0.62 -0.9406 -0.9979 3212908 TimTec1_005485 Clc1ccc(Oc2ccc(/N=C/c3ccc(I)o3)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J08 compound treatment 66360.0 651.0 0.04 57080.0 -93.8 -0.01 0.0217 0.5642 3212909 TimTec1_005486 CC(=O)NC1=NC(=O)/C(=C\c2ccc(C)cc2)/S1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J09 compound treatment 57000.0 -8710.0 -0.5 50360.0 -6810.0 -0.52 -0.7215 -0.9999 3086311 TimTec1_005487 CCn1c2ccccc2c3cc(/C=N/c4ccc(Cl)cc4)ccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J10 compound treatment 56560.0 -9150.0 -0.53 48800.0 -8370.0 -0.63 -0.823 -0.996 1618704 TimTec1_005488 Cc1cc(=O)oc2c(C)c(O)c(CC=C)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J11 compound treatment 62160.0 -3550.0 -0.21 49160.0 -8010.0 -0.61 -0.5743 -0.8967 1654232 TimTec1_005489 CN(CP(=O)(O)CN1CCOCC1)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J12 compound treatment 48600.0 -17100.0 -0.99 36520.0 -20700.0 -1.56 -1.8064 -0.9758 3212910 TimTec1_005490 Clc1ccc(cc1)N2C(=C)C3(CCCCC3)OC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J13 compound treatment 35720.0 -30000.0 -1.74 33760.0 -23400.0 -1.77 -2.4818 -1.0 3212911 TimTec1_005491 OCCn/1c(cs\c1=N/c2ccccc2)c3cccc(c3)N4C(=O)c5ccccc5C4=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J14 compound treatment 1520.0 -64200.0 -3.72 1680.0 -55500.0 -4.2 -5.5999 -0.9982 3086315 TimTec1_005492 OCCn/1c(cs\c1=N/c2cccc(c2)C(F)(F)F)c3ccc(cc3)S(=O)(=O)N4CCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J15 compound treatment 2400.0 -63300.0 -3.67 2560.0 -54600.0 -4.13 -5.5168 -0.9982 1655602 TimTec1_005493 CCOC(=O)C(Cc1ccc(NC(=O)c2ccccc2)cc1)N3C(=O)c4ccccc4C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J16 compound treatment 64080.0 -1630.0 -0.09 51800.0 -5370.0 -0.41 -0.3544 -0.8486 1386199 TimTec1_005494 CC1(C)OC(=O)N(CCCC(=O)O)C1(C)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J17 compound treatment 50720.0 -15000.0 -0.87 43240.0 -13900.0 -1.05 -1.3599 -0.9953 1068676 TimTec1_005495 Cc1ccc(cc1)S(=O)(=O)C=C(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J18 compound treatment 41200.0 -24500.0 -1.42 29880.0 -27300.0 -2.07 -2.4649 -0.9833 3086318 TimTec1_005496 CCOC(=O)C1=C(NC(=S)NC1c2cccc(OC)c2O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J19 compound treatment 58000.0 -7710.0 -0.45 48080.0 -9090.0 -0.69 -0.8025 -0.9781 1433302 TimTec1_005497 COc1cccc(c1)c2nn(CN3CCCC3)c(=S)n2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J20 compound treatment 61960.0 -3750.0 -0.22 54520.0 -2650.0 -0.2 -0.2956 -0.9992 3212912 TimTec1_005498 COc1ccc(CN(C2CC(=O)N(C2=O)c3ccccc3)C(=O)/C=C/C(=O)O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J21 compound treatment 54200.0 -11500.0 -0.67 47360.0 -9810.0 -0.74 -0.9968 -0.9985 3086320 TimTec1_005499 CCOC(=O)c1c(/N=C/c2c(O)ccc3ccccc23)sc4CCCc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J22 compound treatment 55680.0 -10000.0 -0.58 53440.0 -3730.0 -0.28 -0.6107 -0.9452 3212913 TimTec1_005500 CCOc1cc(/C=c/2\sc3nc4c(C)c(C)ccc4n3c2=O)cc(Cl)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J23 mock treatment 67120.0 1410.0 0.08 46520.0 -10700.0 -0.81 -0.5124 -0.6322 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 J24 mock treatment 59600.0 -6110.0 -0.35 50880.0 -6290.0 -0.48 -0.5871 -0.9893 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K01 compound treatment 52080.0 -13600.0 -0.79 48640.0 -8530.0 -0.65 -1.0151 -0.995 1526103 TimTec1_005501 CC(=O)Oc1ccc2oc(c(C(=O)O)c2c1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K02 compound treatment 26680.0 -39000.0 -2.26 24640.0 -32500.0 -2.46 -3.3403 -0.9991 1186869 TimTec1_005502 COc1ccccc1C(=O)Nc2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K03 compound treatment 45480.0 -20200.0 -1.17 42240.0 -14900.0 -1.13 -1.628 -0.9998 3212914 TimTec1_005503 O=C(NC(=S)NC1CCCC1)/C=C/c2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K04 compound treatment 48640.0 -17100.0 -0.99 46600.0 -10600.0 -0.8 -1.2652 -0.9945 3086394 TimTec1_005504 Cc1ccc(cc1)S(=O)(=O)N=C2NCN(CN2)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K05 compound treatment 32520.0 -33200.0 -1.92 31360.0 -25800.0 -1.95 -2.7413 -1.0 1131736 TimTec1_005505 COc1ccc(cc1OC)c2c(C)nn(c2NC(=O)C)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K06 compound treatment 25520.0 -40200.0 -2.33 25440.0 -31700.0 -2.4 -3.345 -0.9999 1007406 TimTec1_005506 COc1ccc(OC(=O)c2ccc(Cl)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K07 compound treatment 56000.0 -9710.0 -0.56 47880.0 -9290.0 -0.7 -0.8952 -0.9939 3212915 TimTec1_005507 Clc1ccccc1C(=O)N=C2NCCCCCN2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K08 compound treatment 9120.0 -56600.0 -3.28 7600.0 -49600.0 -3.75 -4.9717 -0.9977 1323784 TimTec1_005508 Cc1cccc(c1)S(=O)(=O)N2CCSC2c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K09 compound treatment 52480.0 -13200.0 -0.77 44360.0 -12800.0 -0.97 -1.2278 -0.9932 1116167 TimTec1_005509 Cn1c(=O)n(C)c2nc(Br)n(CC(=O)c3ccccc3)c2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K10 compound treatment 52160.0 -13500.0 -0.78 47800.0 -9370.0 -0.71 -1.0568 -0.9987 1464973 TimTec1_005510 OC(=O)c1cc(c2ccccc2)c(cn1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K11 compound treatment 23480.0 -42200.0 -2.45 14720.0 -42500.0 -3.21 -4.0023 -0.9909 3212916 TimTec1_005511 Cc1ccc2nc(Nc3ccc(Cl)cc3)c(/C=N/O)c(=O)n2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K12 compound treatment 53760.0 -11900.0 -0.69 47680.0 -9490.0 -0.72 -0.9977 -0.9998 3086399 TimTec1_005512 Cc1cccc2nc3/C(=N\c4ccccc4)/c5ccccc5-c3nc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K13 compound treatment 50480.0 -15200.0 -0.88 38000.0 -19200.0 -1.45 -1.6501 -0.9715 1486848 TimTec1_005513 CCCc1cc2c(=O)c(coc2cc1O)c3nc4ccccc4n3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K14 compound treatment 50960.0 -14700.0 -0.85 43040.0 -14100.0 -1.07 -1.3607 -0.9938 3086401 TimTec1_005514 CSc1cccc2c(SC)cccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K15 compound treatment 6640.0 -59100.0 -3.42 7480.0 -49700.0 -3.76 -5.0797 -0.9989 3212917 TimTec1_005515 C(N1CCN(CC1)/N=C/c2ccncc2)c3cccc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K16 compound treatment 41640.0 -24100.0 -1.39 43320.0 -13900.0 -1.05 -1.7276 -0.9901 3086404 TimTec1_005516 O=c1/c(=C/C=C/c2ccccc2)/sc3nc4ccccc4n13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K17 compound treatment 51280.0 -14400.0 -0.84 43600.0 -13600.0 -1.03 -1.3176 -0.9948 1919931 TimTec1_005517 Sc1nnc(o1)C2(CCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K18 compound treatment 54480.0 -11200.0 -0.65 49200.0 -7970.0 -0.6 -0.8868 -0.9993 3212918 TimTec1_005518 Cc1ccc(cc1)C2=C/C(=C/c3c(O)ccc4ccccc34)/C(=O)O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K19 compound treatment 24400.0 -41300.0 -2.39 26520.0 -30700.0 -2.32 -3.3331 -0.9999 3086406 TimTec1_005519 COc1ccc(cc1)N2C(=O)CC(S/C(=N/c3ccccc3)/N)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K20 compound treatment 56680.0 -9030.0 -0.52 47520.0 -9650.0 -0.73 -0.8866 -0.9866 3212919 TimTec1_005520 COc1ccc(OCCNS(=O)(=O)c2ccc3c(c2)oc4ccccc43)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K21 compound treatment 32280.0 -33400.0 -1.94 29480.0 -27700.0 -2.1 -2.8518 -0.9992 3086408 TimTec1_005521 Cc1ccccc1C2C(=C(N)SC(=C2C#N)N)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K22 compound treatment 15640.0 -50100.0 -2.9 11840.0 -45300.0 -3.43 -4.4777 -0.9965 3212920 TimTec1_005522 COc1ccc(cc1)C(=O)[C@@H]2[C@@H](c3ccccc3F)C(C#N)(C#N)[C@H]4C=Cc5ccccc5N24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K23 mock treatment 54000.0 -11700.0 -0.68 47720.0 -9450.0 -0.72 -0.9857 -0.9996 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 K24 mock treatment 53560.0 -12100.0 -0.7 50320.0 -6850.0 -0.52 -0.8646 -0.9887 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L01 compound treatment 33520.0 -32200.0 -1.86 27400.0 -29800.0 -2.25 -2.9123 -0.9956 3212921 TimTec1_005523 Oc1ccc(Br)cc1/C=N/c2ccc3nc(SCC(=O)Nc4ccccc4)sc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L02 compound treatment 40160.0 -25500.0 -1.48 30760.0 -26400.0 -2.0 -2.4605 -0.9891 3086411 TimTec1_005524 Fc1cccc(c1)N2C(=O)/C(=C/C=C/c3ccccc3)/SC2=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L03 compound treatment 37520.0 -28200.0 -1.63 42920.0 -14300.0 -1.08 -1.9178 -0.9797 3086413 TimTec1_005525 NC1=C(C#N)C(c2ccsc2)c3ccc4ccccc4c3O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L04 compound treatment 920.0 -64800.0 -3.75 1240.0 -55900.0 -4.23 -5.6481 -0.9982 1682053 TimTec1_005526 Cc1ccc2nc(cn2c1)c3ccc(O)c(O)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L05 compound treatment 41080.0 -24600.0 -1.43 29440.0 -27700.0 -2.1 -2.4934 -0.9823 1536268 TimTec1_005527 Cc1ccc(cc1)N2C(=C(C#N)C(C3=C2CC(C)(C)CC3=O)c4ccccc4)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L06 compound treatment 62240.0 -3470.0 -0.2 51400.0 -5770.0 -0.44 -0.4511 -0.9379 3211217 TimTec1_005528 CC1(C)NN1CCCN2NC2(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L07 compound treatment 67040.0 1330.0 0.08 51160.0 -6010.0 -0.46 -0.2673 -0.579 1273515 TimTec1_005529 OC(=O)c1cc(Cl)c(Cl)cc1C(=O)Nc2ccc(Oc3ccccc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L08 compound treatment 54000.0 -11700.0 -0.68 40040.0 -17100.0 -1.3 -1.3968 -0.9543 1548568 TimTec1_005530 C=CCNC(=O)C1CC1(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L09 compound treatment 8480.0 -57200.0 -3.32 6680.0 -50500.0 -3.82 -5.0472 -0.9975 3211218 TimTec1_005531 Cc1ccc2nc(sc2c1)c3ccc(/N=C\c4ccc[nH]4)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L10 compound treatment 63800.0 -1910.0 -0.11 46320.0 -10900.0 -0.82 -0.6591 -0.7951 1209920 TimTec1_005532 OCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L11 compound treatment 44600.0 -21100.0 -1.22 34840.0 -22300.0 -1.69 -2.0602 -0.9874 1148781 TimTec1_005533 CCN(CC)C(=O)c1ccc(o1)C(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L12 compound treatment 33920.0 -31800.0 -1.84 24080.0 -33100.0 -2.51 -3.0736 -0.9886 3211219 TimTec1_005534 CCc1c(C)[nH]c(C(=O)OCc2ccccc2)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L13 compound treatment 63760.0 -1950.0 -0.11 50080.0 -7090.0 -0.54 -0.4595 -0.8375 1175161 TimTec1_005535 O=P(CCN1CCOCC1)(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L14 compound treatment 71760.0 6050.0 0.35 45240.0 -11900.0 -0.9 -0.3908 -0.4034 3086492 TimTec1_005536 OC(=O)c1ccc(/N=C/c2ccc(OC(=O)c3sc4ccccc4c3Cl)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L15 compound treatment 56200.0 -9510.0 -0.55 46320.0 -10900.0 -0.82 -0.9705 -0.9811 3211220 TimTec1_005537 CCOC(=O)CC1=C(C#N)C(C(=C(N)O1)C(=O)OCC)c2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L16 compound treatment 47040.0 -18700.0 -1.08 34520.0 -22700.0 -1.71 -1.9773 -0.9753 1174009 TimTec1_005538 CCCSc1nnc2c3ccccc3n(Cc4ccccc4)c2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L17 compound treatment 61720.0 -3990.0 -0.23 56160.0 -1010.0 -0.08 -0.2177 -0.8939 3211221 TimTec1_005539 COc1cc(/C=C/2\S/C(=N\c3ccccc3)/N(C2=O)c4ccccc4)cc(OC)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L18 compound treatment 71800.0 6090.0 0.35 55880.0 -1290.0 -0.1 0.1803 0.4923 3211222 TimTec1_005540 CC(=O)N1c2ccccc2C3=NNC(=S)NC13O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L19 compound treatment 64120.0 -1590.0 -0.09 49760.0 -7410.0 -0.56 -0.4619 -0.8122 3086496 TimTec1_005541 COc1cc(/C=N/c2ccc(\N=C\c3ccc(OC(=O)C)c(OC)c3)cc2)ccc1OC(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L20 compound treatment 45440.0 -20300.0 -1.17 37480.0 -19700.0 -1.49 -1.8845 -0.993 3211223 TimTec1_005542 O=C/1N(C2CCCC2)/C(=N\c3ccccc3)/S\C1=C\c4c[nH]c5ccccc45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L21 compound treatment 34320.0 -31400.0 -1.82 28720.0 -28500.0 -2.15 -2.8089 -0.9965 1270230 TimTec1_005543 COC(=O)C1=C(N)N(C2=C(C1c3ccc(OC)cc3)C(=O)CCC2)c4ccc(C)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L22 compound treatment 58280.0 -7430.0 -0.43 46000.0 -11200.0 -0.85 -0.9024 -0.9509 3086498 TimTec1_005544 CC(C)/C=N/N1C(C(C)C)C(C#N)(C#N)C(=C1N)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L23 mock treatment 60680.0 -5030.0 -0.29 56840.0 -334.0 -0.03 -0.2239 -0.7655 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 L24 mock treatment 62760.0 -2950.0 -0.17 51000.0 -6170.0 -0.47 -0.4512 -0.9069 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M01 compound treatment 63240.0 -2470.0 -0.14 59600.0 2430.0 0.18 0.0287 0.1234 1414805 TimTec1_005545 CC(NC(=O)OCc1ccccc1)C(=O)Oc2cc3oc(=O)c(Cl)c(C)c3cc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M02 compound treatment 43760.0 -21900.0 -1.27 40200.0 -17000.0 -1.28 -1.8077 -1.0 3086501 TimTec1_005546 CCOC(=O)C1=C(CSc2nc(CC)c(C)cc2C#N)OC(=C(C#N)C1c3ccc(F)cc3)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M03 compound treatment 49640.0 -16100.0 -0.93 45520.0 -11700.0 -0.88 -1.2821 -0.9996 1514197 TimTec1_005547 Cc1cccc(NCN2C(=O)CSC2=O)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M04 compound treatment 52960.0 -12700.0 -0.74 44080.0 -13100.0 -0.99 -1.2231 -0.9895 1084346 TimTec1_005548 CCOC(=O)Cc1nc2ccccc2[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M05 compound treatment 24920.0 -40800.0 -2.36 23280.0 -33900.0 -2.57 -3.4852 -0.9992 1367503 TimTec1_005549 CC(C)C(NS(=O)(=O)c1ccc(C)cc1)C(=O)Oc2ccc3c4CCCCc4c(=O)oc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M06 compound treatment 55040.0 -10700.0 -0.62 42720.0 -14500.0 -1.09 -1.2107 -0.9635 1003422 TimTec1_005550 CC(=O)Oc1ccc(cc1)C(=O)c2ccc(OC(=O)C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M07 compound treatment 42280.0 -23400.0 -1.36 31160.0 -26000.0 -1.97 -2.3522 -0.9835 3085493 TimTec1_005551 CC1=C(N(N/C(=N\CC=C)/S1)c2ccc3OCCOc3c2)C(=O)Nc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M08 compound treatment 57320.0 -8390.0 -0.49 49360.0 -7810.0 -0.59 -0.7619 -0.9952 1442839 TimTec1_005552 OCCN1CCN(CC1)C(=O)Nc2cccc(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M09 compound treatment 58440.0 -7270.0 -0.42 42280.0 -14900.0 -1.13 -1.095 -0.9098 1468923 TimTec1_005553 CCOC(=O)c1c(N)cc2[nH]c(=S)[nH]c(=O)c2c1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M10 compound treatment 10400.0 -55300.0 -3.2 10120.0 -47100.0 -3.56 -4.7844 -0.9986 3085496 TimTec1_005554 Cc1ccccc1c2nccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M11 compound treatment 60240.0 -5470.0 -0.32 44960.0 -12200.0 -0.92 -0.8778 -0.8982 1298715 TimTec1_005555 CCOC(=O)NS(=O)(=O)c1ccc(C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M12 compound treatment 30480.0 -35200.0 -2.04 21280.0 -35900.0 -2.72 -3.3644 -0.9901 3211224 TimTec1_005556 Cc1ccc-2c(c1)/C(=C/c3ccncc3)/c4cc5ccccc5nc42 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M13 compound treatment 62720.0 -2990.0 -0.17 39000.0 -18200.0 -1.38 -1.0952 -0.7899 1313295 TimTec1_005557 Cc1c(OCC(=O)OCc2ccccc2)ccc3c4ccccc4c(=O)oc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M14 compound treatment 33640.0 -32100.0 -1.86 23480.0 -33700.0 -2.55 -3.1172 -0.9879 1489666 TimTec1_005558 COC(=O)C(C)N(C(=O)c1c(F)cccc1F)c2c(C)cccc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M15 compound treatment 62600.0 -3110.0 -0.18 46360.0 -10800.0 -0.82 -0.7062 -0.8425 1632514 TimTec1_005559 Clc1ccccc1N2C(=O)CC(Nc3ccccc3)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M16 compound treatment 6440.0 -59300.0 -3.43 3000.0 -54200.0 -4.1 -5.3277 -0.9961 3085499 TimTec1_005560 CCOC(=O)CSC1=NC(=O)/C(=C\c2ccc(Cl)cc2)/S1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M17 compound treatment 64760.0 -949.0 -0.05 44080.0 -13100.0 -0.99 -0.7397 -0.7452 3211225 TimTec1_005561 CC1(C)OC(=O)N(Cc2ccccc2)C1=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M18 compound treatment 5560.0 -60100.0 -3.48 3320.0 -53900.0 -4.08 -5.3466 -0.997 1242728 TimTec1_005562 Cc1ccc(NS(=O)(=O)c2ccc(cc2)N3C(=O)c4ccccc4C3=O)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M19 compound treatment 12440.0 -53300.0 -3.09 10400.0 -46800.0 -3.54 -4.6858 -0.9977 1175444 TimTec1_005563 CCOc1ccc2nc(SCc3c[nH]c4ccccc34)sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M20 compound treatment 67120.0 1410.0 0.08 56480.0 -694.0 -0.05 0.0207 0.2129 1133231 TimTec1_005564 Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)NCc2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M21 compound treatment 59480.0 -6230.0 -0.36 48720.0 -8450.0 -0.64 -0.7077 -0.9633 3085503 TimTec1_005565 COc1cc(/C=N/c2c(nc3ccccn23)c4ccc(O)c(OC)c4)ccc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M22 compound treatment 55800.0 -9910.0 -0.57 50560.0 -6610.0 -0.5 -0.7599 -0.9977 3211226 TimTec1_005566 CC(=O)N1CC=C2[C@H](C1)[C@@H](c3ccc(F)cc3F)C(C#N)(C#N)C(=C2C#N)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M23 mock treatment 65400.0 -309.0 -0.02 60280.0 3110.0 0.24 0.1536 0.6514 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 M24 mock treatment 66240.0 531.0 0.03 55880.0 -1290.0 -0.1 -0.0475 -0.4626 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N01 compound treatment 880.0 -64800.0 -3.76 720.0 -56500.0 -4.27 -5.6775 -0.9979 2116249 TimTec1_005567 O=C/1NC(=S)N(C(=O)\C1=C\c2c[nH]c3ccccc23)c4cccc5ccccc45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N02 compound treatment 60760.0 -4950.0 -0.29 53200.0 -3970.0 -0.3 -0.4154 -0.9997 1630568 TimTec1_005568 CC(=Cc1c(O)nc2ccccn2c1=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N03 compound treatment 28400.0 -37300.0 -2.16 20600.0 -36600.0 -2.77 -3.486 -0.9925 1455275 TimTec1_005569 CCOC(=O)CCC1(CCC(=O)OCC)c2ccccc2-c3nc4ccccc4cc31 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N04 compound treatment 46520.0 -19200.0 -1.11 39400.0 -17800.0 -1.35 -1.7374 -0.9955 1423540 TimTec1_005570 CCNC(=O)C1CN(C(=O)C1)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N05 compound treatment 46760.0 -18900.0 -1.1 38440.0 -18700.0 -1.42 -1.779 -0.992 3211227 TimTec1_005571 S/C(=C(/C(=O)c1ccccc1)\[n+]2ccccc2)/Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N06 compound treatment 1760.0 -63900.0 -3.71 1480.0 -55700.0 -4.22 -5.6008 -0.9979 3085508 TimTec1_005572 CCOC(=O)Cn/1c(cs\c1=N/c2ccc(F)cc2)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N07 compound treatment 49600.0 -16100.0 -0.93 39760.0 -17400.0 -1.32 -1.592 -0.9857 3211228 TimTec1_005573 S=c1[nH]nc([nH]1)C2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N08 compound treatment 41840.0 -23900.0 -1.38 33400.0 -23800.0 -1.8 -2.2503 -0.9915 1670836 TimTec1_005574 COc1ccc2C(=O)C(CCc2c1C)C3(O)C(=O)N(C)c4ccccc43 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N09 compound treatment 31640.0 -34100.0 -1.97 23640.0 -33500.0 -2.54 -3.1906 -0.9923 2116264 TimTec1_005575 Cc1[nH]c2ccccc2c1/C=N/c3ccc(\N=C\c4c(C)[nH]c5ccccc45)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N10 compound treatment 52000.0 -13700.0 -0.79 36960.0 -20200.0 -1.53 -1.6435 -0.9534 1703166 TimTec1_005576 Cn1c(SCC(=O)N2CCCCC2)nc3n(C)c(=O)n(C)c(=O)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N11 compound treatment 49320.0 -16400.0 -0.95 34560.0 -22600.0 -1.71 -1.8818 -0.9613 3211229 TimTec1_005577 COc1ccc(cc1)n2nc(C#N)c(N)c(C#N)c2=N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N12 compound treatment 59920.0 -5790.0 -0.34 42480.0 -14700.0 -1.11 -1.0236 -0.8811 3085531 TimTec1_005578 O=C(Cn1nnc2ccccc12)C3CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N13 compound treatment 45240.0 -20500.0 -1.19 29520.0 -27700.0 -2.09 -2.3187 -0.9638 1157884 TimTec1_005579 Cc1ccc(cc1C)c2csc(Nc3ccc4OCOc4c3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N14 compound treatment 21120.0 -44600.0 -2.58 13400.0 -43800.0 -3.31 -4.1697 -0.9924 1380401 TimTec1_005580 CCOc1ccc(cc1)N2C(=O)CC(N(Cc3ccc(Cl)cc3)C(=O)c4ccc(Cl)cc4)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N15 compound treatment 55240.0 -10500.0 -0.61 47600.0 -9570.0 -0.72 -0.9413 -0.9961 3085535 TimTec1_005581 OC(=O)CN1C(=O)/C(=C\c2ccsc2)/SC1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N16 compound treatment 41040.0 -24700.0 -1.43 30600.0 -26600.0 -2.01 -2.433 -0.986 3211425 TimTec1_005582 Oc1ccccc1/C=N/c2ccc3nc(SCC(=O)NCCOc4ccccc4)sc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N17 compound treatment 50320.0 -15400.0 -0.89 43280.0 -13900.0 -1.05 -1.3741 -0.9966 1583377 TimTec1_005583 CC1CN(CN2C(=O)c3ccccc3C2=O)CC(C)O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N18 compound treatment 59120.0 -6590.0 -0.38 44120.0 -13100.0 -0.99 -0.9686 -0.9144 1137144 TimTec1_005584 Nc1nnc(CCN2CCCCC2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N19 compound treatment 60560.0 -5150.0 -0.3 48200.0 -8970.0 -0.68 -0.6912 -0.9318 3211426 TimTec1_005585 CC1=C(C(NC(=O)N1)c2ccc3OCOc3c2)C(=O)OCC(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N20 compound treatment 58320.0 -7390.0 -0.43 53600.0 -3570.0 -0.27 -0.494 -0.9755 3211427 TimTec1_005586 COc1cc(/C=C\2/S/C(=N/Cc3ccccc3)/N(Cc4ccccc4)C2=O)cc(OC)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N21 compound treatment 43000.0 -22700.0 -1.32 30920.0 -26300.0 -1.99 -2.3355 -0.9799 3085538 TimTec1_005587 Cc1ccc(/C=N/c2ccc(Nc3ccccc3)cc2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N22 compound treatment 24400.0 -41300.0 -2.39 12880.0 -44300.0 -3.35 -4.0631 -0.9863 1176605 TimTec1_005588 Fc1ccc(cc1)c2nc3c([nH]2)c4ccccc4c5ccccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N23 mock treatment 60280.0 -5430.0 -0.31 53560.0 -3610.0 -0.27 -0.4158 -0.9976 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 N24 mock treatment 56720.0 -8990.0 -0.52 50240.0 -6930.0 -0.52 -0.7394 -1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O01 compound treatment 28600.0 -37100.0 -2.15 16680.0 -40500.0 -3.07 -3.6877 -0.985 1527225 TimTec1_005589 CCc1cc2c(=O)c(c3nc4ccccc4[nH]3)c(C)oc2cc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O02 compound treatment 5360.0 -60300.0 -3.5 4600.0 -52600.0 -3.98 -5.2863 -0.9979 3085541 TimTec1_005590 NC1=C(C#N)C2=CCSC[C@H]2[C@H](c3cccc(Cl)c3)C1(C#N)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O03 compound treatment 43800.0 -21900.0 -1.27 35520.0 -21700.0 -1.64 -2.0566 -0.992 1190084 TimTec1_005591 CCOc1ccccc1C(=O)NCCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O04 compound treatment 52640.0 -13100.0 -0.76 38440.0 -18700.0 -1.42 -1.5381 -0.9568 1047189 TimTec1_005592 Clc1ccc(cc1)S(=O)(=O)N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O05 compound treatment 42400.0 -23300.0 -1.35 27000.0 -30200.0 -2.28 -2.5699 -0.9686 3211428 TimTec1_005593 CC(C)(C)OC(=O)C1CCC(CN1)C(=O)Oc2ccc3c4CCCCc4c(=O)oc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O06 compound treatment 70360.0 4650.0 0.27 45320.0 -11900.0 -0.9 -0.4439 -0.4738 1652072 TimTec1_005594 COC(=O)C1C(C(C(=O)OC)C(C)(O)CC1=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O07 compound treatment 41160.0 -24500.0 -1.42 28720.0 -28500.0 -2.15 -2.5287 -0.9797 3211429 TimTec1_005595 Clc1cccc(NC(=O)N=C2NCCCCCN2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O08 compound treatment 61600.0 -4110.0 -0.24 41640.0 -15500.0 -1.18 -0.9998 -0.8334 1649723 TimTec1_005596 CC(C)CN1C(=O)N(C(n2oc(=O)n(c3ccccc3)c2=O)C1(C)C)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O09 compound treatment 42440.0 -23300.0 -1.35 27240.0 -29900.0 -2.27 -2.5555 -0.9692 1511407 TimTec1_005597 CCc1c(C)c(C#N)c2nc3ccccc3n2c1NCc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O10 compound treatment 35320.0 -30400.0 -1.76 23800.0 -33400.0 -2.53 -3.0313 -0.9844 3085546 TimTec1_005598 Cc1ccccc1c2ccc3cccc(C)c3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O11 compound treatment 69320.0 3610.0 0.21 49320.0 -7850.0 -0.59 -0.2724 -0.4323 3211430 TimTec1_005599 S(c1nnc[nH]1)c2nc3ccccc3nc2Sc4nnc[nH]4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O12 compound treatment 52840.0 -12900.0 -0.75 33760.0 -23400.0 -1.77 -1.7804 -0.926 1067246 TimTec1_005600 COc1ccc(C)c2C(=O)CCCc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O13 compound treatment 61480.0 -4230.0 -0.25 47520.0 -9650.0 -0.73 -0.69 -0.8952 1520144 TimTec1_005601 CC(NC(=O)OCc1ccccc1)C(=O)Oc2ccc3c(=O)c(coc3c2)c4ccc(F)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O14 compound treatment 70680.0 4970.0 0.29 45040.0 -12100.0 -0.92 -0.4458 -0.4631 1641803 TimTec1_005602 Clc1cc(OC(=O)C2CCCCC2)ccc1OC(=O)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O15 compound treatment 43080.0 -22600.0 -1.31 21840.0 -35300.0 -2.67 -2.8183 -0.9462 3211431 TimTec1_005603 OC1=C(C#N)[C@@H]([C@H](C(=O)N1CCc2ccccc2)[n+]3ccccc3)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O16 compound treatment 73320.0 7610.0 0.44 55280.0 -1890.0 -0.14 0.2105 0.4539 1578376 TimTec1_005604 Cc1cc(=O)oc2cc(OC(=O)c3cc4ccccc4o3)ccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O17 compound treatment 38120.0 -27600.0 -1.6 25160.0 -32000.0 -2.42 -2.8438 -0.9796 3211432 TimTec1_005605 CCc1nc(SC/C=C/c2ccccc2)c(C#N)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O18 compound treatment 68560.0 2850.0 0.17 45360.0 -11800.0 -0.89 -0.5155 -0.5669 1218415 TimTec1_005606 CCOC(=O)C1=C(C)NC(=S)NC1c2ccc(OCC(=O)N3CCCCC3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O19 compound treatment 69880.0 4170.0 0.24 43680.0 -13500.0 -1.02 -0.5514 -0.5253 1784221 TimTec1_005607 CCc1oc2ccccc2c1C(=O)CCN3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O20 compound treatment 57760.0 -7950.0 -0.46 37360.0 -19800.0 -1.5 -1.3862 -0.8835 3085555 TimTec1_005608 Cc1c(Cl)cccc1NC2=NS(=O)(=O)c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O21 compound treatment 64320.0 -1390.0 -0.08 52560.0 -4610.0 -0.35 -0.3038 -0.8478 1638741 TimTec1_005609 CC(C)NC(=O)C1CN(CCN1S(=O)(=O)c2ccccc2)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O22 compound treatment 64120.0 -1590.0 -0.09 45200.0 -12000.0 -0.91 -0.706 -0.7749 3211433 TimTec1_005610 COc1ccc(cc1)C(=O)CSc2nsc(SCC(=O)c3ccc(OC)cc3)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O23 mock treatment 69640.0 3930.0 0.23 52560.0 -4610.0 -0.35 -0.0859 -0.206 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 O24 mock treatment 70880.0 5170.0 0.3 63680.0 6510.0 0.49 0.5601 0.9716 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P01 compound treatment 39360.0 -26300.0 -1.53 23000.0 -34200.0 -2.59 -2.9086 -0.9684 3085557 TimTec1_005611 Oc1ccc(Br)cc1/C=N/CC2CCCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P02 compound treatment 59360.0 -6350.0 -0.37 42920.0 -14300.0 -1.08 -1.023 -0.8975 1175377 TimTec1_005612 Sc1nnc2c3ccccc3n(Cc4ccccc4)c2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P03 compound treatment 28080.0 -37600.0 -2.18 19720.0 -37500.0 -2.84 -3.5463 -0.9916 3211434 TimTec1_005613 Cc1ccccc1c2nnc3-c4ccccc4CC(C)(C)n23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P04 compound treatment 51480.0 -14200.0 -0.82 33960.0 -23200.0 -1.76 -1.8254 -0.9405 1673398 TimTec1_005614 CCCC1C(C2c3ccccc3C1c4ccccc24)C(=O)Nc5ccccc5OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P05 compound treatment 49240.0 -16500.0 -0.95 35440.0 -21700.0 -1.65 -1.838 -0.9664 1642050 TimTec1_005615 N#Cc1ccc(cc1C#N)n2nnc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P06 compound treatment 66240.0 531.0 0.03 47640.0 -9530.0 -0.72 -0.4885 -0.6763 1492547 TimTec1_005616 CC1(C)CC(=O)c2cc(c3ccc(Br)cc3)n(CC(=O)O)c2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P07 compound treatment 57840.0 -7870.0 -0.46 43520.0 -13700.0 -1.03 -1.0532 -0.9323 3085561 TimTec1_005617 Oc1ccc(/C=N/c2ccc3[nH]c(=O)[nH]c3c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P08 compound treatment 38040.0 -27700.0 -1.6 24000.0 -33200.0 -2.51 -2.9091 -0.9765 3211435 TimTec1_005618 CCOc1ccc2ccccc2c1/C=C/3\C(=O)NC(=S)N(C3=O)c4cccc(Cl)c4Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P09 compound treatment 44400.0 -21300.0 -1.23 32480.0 -24700.0 -1.87 -2.1947 -0.9797 3085562 TimTec1_005619 COc1cccc(c1)c2nnc(SCC(=O)NCCOc3ccccc3)n2c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P10 compound treatment 69960.0 4250.0 0.25 53520.0 -3650.0 -0.28 -0.0214 -0.0578 3211436 TimTec1_005620 Cn1cnnc1SCN2C(=O)c3ccccc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P11 compound treatment 62280.0 -3430.0 -0.2 39400.0 -17800.0 -1.35 -1.0918 -0.8028 1443624 TimTec1_005621 CCOP(=O)(C)C1(CC1)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P12 compound treatment 7280.0 -58400.0 -3.39 4560.0 -52600.0 -3.98 -5.2098 -0.9967 1354424 TimTec1_005622 CCN(CC)C(=O)C1(CC1)P(=O)(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P13 compound treatment 50760.0 -14900.0 -0.87 44760.0 -12400.0 -0.94 -1.2769 -0.9992 1466364 TimTec1_005623 COCc1cc(C)c2c(n1)sc3c4nc5ccccc5n4c(C)nc32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P14 compound treatment 26280.0 -39400.0 -2.28 24280.0 -32900.0 -2.49 -3.3759 -0.9991 3211437 TimTec1_005624 C=CCN/1C(=O)/C(=C\c2cccs2)/S\C1=N\c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P15 compound treatment 35880.0 -29800.0 -1.73 33760.0 -23400.0 -1.77 -2.4752 -0.9999 1444037 TimTec1_005625 Nc1nc(CCc2ccccc2)c(C#N)c(N)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P16 compound treatment 43600.0 -22100.0 -1.28 32320.0 -24900.0 -1.88 -2.236 -0.9825 3085567 TimTec1_005626 COc1ccc2NC(=O)/C(=C/3\SC(=S)NC3=O)/c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P17 compound treatment 17960.0 -47700.0 -2.77 14120.0 -43100.0 -3.26 -4.2606 -0.9967 1603829 TimTec1_005627 Nc1nc(CSc2nc3ccccc3s2)nc(Nc4ccccc4)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P18 compound treatment 8920.0 -56800.0 -3.29 5280.0 -51900.0 -3.93 -5.1041 -0.9961 1171831 TimTec1_005628 Cc1ccc(Nc2nc(C)nc3c4ccccc4oc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P19 compound treatment 47760.0 -17900.0 -1.04 40800.0 -16400.0 -1.24 -1.6117 -0.9962 1524350 TimTec1_005629 COC(=O)c1ccc(NC(=O)Cn2nc(SC)n(N)c2=S)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P20 compound treatment 51280.0 -14400.0 -0.84 42120.0 -15100.0 -1.14 -1.3969 -0.9884 3211438 TimTec1_005630 CCOC(=O)/C=C/c1ccco1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P21 compound treatment 54400.0 -11300.0 -0.66 52720.0 -4450.0 -0.34 -0.7017 -0.9523 3211439 TimTec1_005631 CCOC(=O)C1C2NC(=S)N[C@]1(C)Oc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P22 compound treatment 62840.0 -2870.0 -0.17 48120.0 -9050.0 -0.69 -0.6021 -0.8538 3085589 TimTec1_005632 COc1cc(/C=C\2/C(=NN(C2=O)c3ccc(Cl)c(c3)C(=O)O)C)ccc1OCC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P23 mock treatment 53800.0 -11900.0 -0.69 48280.0 -8890.0 -0.67 -0.9639 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2078 P24 mock treatment 51480.0 -14200.0 -0.82 46960.0 -10200.0 -0.77 -1.1296 -0.9995 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A01 compound treatment 59840.0 7620.0 0.44 53240.0 2910.0 0.22 0.4676 0.9484 3211440 TimTec1_005633 CC(=O)n1cc(/C=c\2/sc3nc4c(C)c(C)ccc4n3c2=O)c(n1)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A02 compound treatment 6320.0 -45900.0 -2.66 12440.0 -37900.0 -2.87 -3.9087 -0.9993 3085592 TimTec1_005634 Cc1nc(N)sc1c2csc(Nc3cccc(Cl)c3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A03 compound treatment 28280.0 -23900.0 -1.39 36320.0 -14000.0 -1.06 -1.7309 -0.9912 3211529 TimTec1_005635 CCC(=O)N1N=C(CC1(O)c2ccc(F)cc2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A04 compound treatment 49640.0 -2580.0 -0.15 41800.0 -8530.0 -0.65 -0.5625 -0.8485 1419705 TimTec1_005636 CC1CCC(=C(C#N)C(=O)NCc2ccccc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A05 compound treatment 14880.0 -37300.0 -2.16 16960.0 -33400.0 -2.53 -3.3161 -0.997 1732858 TimTec1_005637 Fc1ccc2C(=O)N(C3CCCCCCC3)C(=O)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A06 compound treatment 53320.0 1100.0 0.06 49480.0 -853.0 -0.06 -7.0E-4 -0.0079 3211530 TimTec1_005638 Fc1ccc(cc1)C2Nc3ccc(OC(F)(F)F)cc3C4C=CCC42 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A07 compound treatment 43560.0 -8660.0 -0.5 46320.0 -4010.0 -0.3 -0.5697 -0.971 1737054 TimTec1_005639 Nn1c(CO)nc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A08 compound treatment 47560.0 -4660.0 -0.27 48720.0 -1610.0 -0.12 -0.2774 -0.9355 1175030 TimTec1_005640 CC(C)(O)c1cn2ccccc2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A09 compound treatment 43200.0 -9020.0 -0.52 38040.0 -12300.0 -0.93 -1.0276 -0.9628 1364286 TimTec1_005641 COc1ccc(cc1)C(CC#N)C2CCOC(C)(C)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A10 compound treatment 37560.0 -14700.0 -0.85 41600.0 -8730.0 -0.66 -1.0681 -0.9923 1357576 TimTec1_005642 O=C(NCCc1ccc(cc1)S(=O)(=O)N2CCCC2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A11 compound treatment 10680.0 -41500.0 -2.41 9440.0 -40900.0 -3.1 -3.8907 -0.9923 3211531 TimTec1_005643 CNC(=S)N(C)/N=C\1/C(=O)N(Cc2c(Cl)cccc2Cl)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A12 compound treatment 45640.0 -6580.0 -0.38 47120.0 -3210.0 -0.24 -0.4417 -0.9764 3085598 TimTec1_005644 CCc1nn2c(C)cc(O)nc2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A13 compound treatment 47040.0 -5180.0 -0.3 47120.0 -3210.0 -0.24 -0.3843 -0.9945 1530862 TimTec1_005645 C1Cc2c(C1)c3c(ccc4ccccc43)nc2c5cccs5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A14 compound treatment 46840.0 -5380.0 -0.31 51880.0 1550.0 0.12 -0.1377 -0.4134 1575017 TimTec1_005646 CC1CN(OC(O1)c2ccc3OCOc3c2)C(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A15 compound treatment 41720.0 -10500.0 -0.61 44080.0 -6250.0 -0.47 -0.765 -0.9923 3085600 TimTec1_005647 OC(=O)C1CC(=O)N(Cc2ccccc2)/C(=N/c3ccc(F)cc3)/S1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A16 compound treatment 51520.0 -704.0 -0.04 42800.0 -7530.0 -0.57 -0.432 -0.7557 1628881 TimTec1_005648 CCC(N)C1(CC2CC3CC(C2)C1)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A17 compound treatment 49640.0 -2580.0 -0.15 40880.0 -9450.0 -0.72 -0.6118 -0.8369 3085602 TimTec1_005649 FC(F)(F)c1cccc(NCn2c(=S)oc3ccc(Cl)cc23)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A18 compound treatment 34360.0 -17900.0 -1.03 32960.0 -17400.0 -1.32 -1.6617 -0.993 1127153 TimTec1_005650 CC(C)c1ccccc1NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A19 compound treatment 45440.0 -6780.0 -0.39 48960.0 -1370.0 -0.1 -0.3514 -0.8643 1348096 TimTec1_005651 CN(C)c1nc2n(C)c(=O)n(C)c(=O)c2n1CC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A20 compound treatment 57920.0 5700.0 0.33 47200.0 -3130.0 -0.24 0.0657 0.1617 1611764 TimTec1_005652 COC(=O)CCn1cc(F)c(N)nc1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A21 compound treatment 47880.0 -4340.0 -0.25 47720.0 -2610.0 -0.2 -0.3178 -0.9929 1564099 TimTec1_005653 CN(C)N=Nc1ccc(cc1)S(=O)(=O)NC(=O)Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A22 compound treatment 46040.0 -6180.0 -0.36 46360.0 -3970.0 -0.3 -0.466 -0.9962 1394944 TimTec1_005654 C=CCn1c(SCc2nc3ccccc3[nH]2)nnc1c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A23 mock treatment 53240.0 1020.0 0.06 48480.0 -1850.0 -0.14 -0.0575 -0.3782 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 A24 mock treatment 61720.0 9500.0 0.55 50680.0 348.0 0.03 0.4076 0.7401 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B01 compound treatment 55880.0 3660.0 0.21 54560.0 4230.0 0.32 0.3761 0.9799 3211532 TimTec1_005655 SC1=NC(=O)/C(=C\c2cccnc2)/S1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B02 compound treatment 40160.0 -12100.0 -0.7 46600.0 -3730.0 -0.28 -0.694 -0.9206 1491875 TimTec1_005656 COc1ccc(cc1)S(=O)(=O)NCCC2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B03 compound treatment 49760.0 -2460.0 -0.14 54600.0 4270.0 0.32 0.1275 0.361 3085609 TimTec1_005657 Cc1nn(c(O)c1CCC#N)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B04 compound treatment 45200.0 -7020.0 -0.41 43800.0 -6530.0 -0.49 -0.6374 -0.9953 3211533 TimTec1_005658 FC(F)(F)C(NCC1(CC2CC3CC(C2)C1)C3)(NC(=O)c4ccccc4)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B05 compound treatment 51120.0 -1100.0 -0.06 46200.0 -4130.0 -0.31 -0.2664 -0.8344 3085612 TimTec1_005659 COc1cc(NC=C2C(=O)NC(=O)NC2=O)cc(OC)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B06 compound treatment 49680.0 -2540.0 -0.15 40480.0 -9850.0 -0.75 -0.6316 -0.8308 3085613 TimTec1_005660 Cc1cc(cc(C)c1O)C(O)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B07 compound treatment 19000.0 -33200.0 -1.92 18000.0 -32300.0 -2.45 -3.0917 -0.9929 3211534 TimTec1_005661 FC(F)(F)c1ccccc1C2C3=C(CCCC3=O)Nc4ccc5ncccc5c24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B08 compound treatment 43760.0 -8460.0 -0.49 36680.0 -13700.0 -1.03 -1.0775 -0.942 1339353 TimTec1_005662 CCc1ccc(cc1)C(=O)c2c(c(c3cc(ccn23)C(C)(C)C)S(=O)(=O)CC)S(=O)(=O)CC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B09 compound treatment 44440.0 -7780.0 -0.45 41040.0 -9290.0 -0.7 -0.8163 -0.9769 1735427 TimTec1_005663 CC1(C)CC(=O)CC(C)(C)N1OC(=O)c2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B10 compound treatment 40520.0 -11700.0 -0.68 39880.0 -10500.0 -0.79 -1.0389 -0.9971 1503527 TimTec1_005664 CCC(NC(=O)c1ccc(cc1)S(=O)(=O)N2CCOCC2)C3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B11 compound treatment 46680.0 -5540.0 -0.32 42840.0 -7490.0 -0.57 -0.6281 -0.9637 1555325 TimTec1_005665 CCOc1ccccc1NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B12 compound treatment 46920.0 -5300.0 -0.31 40000.0 -10300.0 -0.78 -0.7703 -0.9167 3085617 TimTec1_005666 COc1ccc(/C=N/n2c(=O)c(nn3cnnc23)C(C)(C)C)c(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B13 compound treatment 37480.0 -14700.0 -0.85 39800.0 -10500.0 -0.8 -1.1678 -0.9994 1402991 TimTec1_005667 Cc1ccc(Oc2cc(C#N)c(C#N)cc2n3nnc4ccccc34)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B14 compound treatment 18760.0 -33500.0 -1.94 21720.0 -28600.0 -2.17 -2.9024 -0.9985 3085619 TimTec1_005668 CC/N=C\1/S/C(=C/c2sccc2C)/C(=O)N1CC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B15 compound treatment 1440.0 -50800.0 -2.94 1400.0 -48900.0 -3.7 -4.6996 -0.9935 1257857 TimTec1_005669 OC1=C(C(C#Cc2ccccc2)C3=C(O)CCCC3=O)C(=O)CCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B16 compound treatment 36880.0 -15300.0 -0.89 31800.0 -18500.0 -1.4 -1.6205 -0.9758 1631021 TimTec1_005670 COc1ccccc1N2CCN(CC2)S(=O)(=O)c3c(C)ccc4nsnc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B17 compound treatment 51760.0 -464.0 -0.03 48160.0 -2170.0 -0.16 -0.1353 -0.8119 1219783 TimTec1_005671 COc1ccc(cc1)N2C(=O)NC(=O)C(Cc3ccc(O)c(OC)c3)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B18 compound treatment 38440.0 -13800.0 -0.8 41920.0 -8410.0 -0.64 -1.015 -0.9937 3211535 TimTec1_005672 Cc1cc(NC(=O)NC(=O)c2ccc(F)cc2)n[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B19 compound treatment 58920.0 6700.0 0.39 53520.0 3190.0 0.24 0.4449 0.9739 1033315 TimTec1_005673 Cc1cc(C)n(n1)C(=S)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B20 compound treatment 34960.0 -17300.0 -1.0 35680.0 -14700.0 -1.11 -1.4915 -0.9987 3085624 TimTec1_005674 CSc1snc(O)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B21 compound treatment 9720.0 -42500.0 -2.46 7840.0 -42500.0 -3.22 -4.0157 -0.9913 3211536 TimTec1_005675 CCc1ccc(cc1)C2=Nn3c(C)nnc3SC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B22 compound treatment 66360.0 14100.0 0.82 60720.0 10400.0 0.79 1.1351 0.9998 3085626 TimTec1_005676 O=C(Nc1cccc(c1)c2nnc(o2)c3ccco3)C(c4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B23 mock treatment 54240.0 2020.0 0.12 53200.0 2870.0 0.22 0.2361 0.9578 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 B24 mock treatment 57640.0 5420.0 0.31 58320.0 7990.0 0.6 0.6494 0.9534 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C01 compound treatment 21320.0 -30900.0 -1.79 20920.0 -29400.0 -2.23 -2.8403 -0.9942 1675170 TimTec1_005677 C(Oc1cccc(c1)c2nnc3ccc4ccccc4n23)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C02 compound treatment 45320.0 -6900.0 -0.4 49000.0 -1330.0 -0.1 -0.3542 -0.8585 1346658 TimTec1_005678 Fc1ccccc1C2Nc3ccc4ccccc4c3C5C=CCC52 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C03 compound treatment 55520.0 3300.0 0.19 51440.0 1110.0 0.08 0.1943 0.9317 3085628 TimTec1_005679 COC(C)n1cc(Br)c(=O)[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C04 compound treatment 35400.0 -16800.0 -0.97 30440.0 -19900.0 -1.51 -1.754 -0.9778 1681244 TimTec1_005680 Cc1cc(Oc2cc(C#N)c3ccccc3n2)ccc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C05 compound treatment 47120.0 -5100.0 -0.3 49800.0 -533.0 -0.04 -0.2376 -0.7961 3085667 TimTec1_005681 Fc1ccc2C(=O)N(N3CCOCC3)C(=O)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C06 compound treatment 31840.0 -20400.0 -1.18 34480.0 -15900.0 -1.2 -1.6836 -1.0 1270347 TimTec1_005682 Cn1c(=N)n(CC(=O)C2(CC3CC4CC(C3)C2)C4)c5ccccc15 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C07 compound treatment 7520.0 -44700.0 -2.59 10720.0 -39600.0 -3.0 -3.9516 -0.9973 1454435 TimTec1_005683 CSc1nc2-c3ccccc3CC(C)(C)c2c(=O)n1Cc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C08 compound treatment 46360.0 -5860.0 -0.34 50600.0 268.0 0.02 -0.2259 -0.6638 1371600 TimTec1_005684 Cc1ccc(cc1)C(=O)Cn2c(=N)n(C)c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C09 compound treatment 38320.0 -13900.0 -0.81 34280.0 -16100.0 -1.22 -1.4288 -0.9801 1605543 TimTec1_005685 CSC1=NC2(Cc3ccccc13)CCCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C10 compound treatment 33120.0 -19100.0 -1.11 33760.0 -16600.0 -1.25 -1.6697 -0.9981 1564745 TimTec1_005686 CC(C)(O)C#Cc1ccc(cc1)C(=O)NCC(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C11 compound treatment 19880.0 -32300.0 -1.87 21800.0 -28500.0 -2.16 -2.8522 -0.9975 3085653 TimTec1_005687 O=C(Nc1ccccc1)OCC23COC(N3C(OC2)c4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C12 compound treatment 38800.0 -13400.0 -0.78 34240.0 -16100.0 -1.22 -1.4113 -0.9765 1696532 TimTec1_005688 O=C1N(C(Nc2ccccc12)c3cccs3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C13 compound treatment 43600.0 -8620.0 -0.5 35360.0 -15000.0 -1.13 -1.1547 -0.9323 3211537 TimTec1_005689 Cc1ccc(/N=C/2\NC(=O)C(Cc3cccc(c3)C(F)(F)F)S2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C14 compound treatment 42680.0 -9540.0 -0.55 34280.0 -16100.0 -1.22 -1.2502 -0.9365 1190215 TimTec1_005690 CC(C1Nc2ccccc2C(=O)N1c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C15 compound treatment 25760.0 -26500.0 -1.53 24400.0 -25900.0 -1.96 -2.4722 -0.9925 1378935 TimTec1_005691 CCOC(=O)c1c(NC(=O)CSc2ncccn2)sc3CCCc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C16 compound treatment 42960.0 -9260.0 -0.54 41360.0 -8970.0 -0.68 -0.8598 -0.9932 1327450 TimTec1_005692 CCC(=O)Nc1nonc1c2nc3ccccc3n2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C17 compound treatment 42320.0 -9900.0 -0.57 37920.0 -12400.0 -0.94 -1.0701 -0.972 3211622 TimTec1_005693 CCC(=O)NC(Nc1sc2CCCCc2c1C#N)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C18 compound treatment 43280.0 -8940.0 -0.52 48480.0 -1850.0 -0.14 -0.4656 -0.8673 1168333 TimTec1_005694 CC(C)CCN1NC2(CCCCC2)NC1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C19 compound treatment 40480.0 -11700.0 -0.68 36800.0 -13500.0 -1.02 -1.2054 -0.9802 3211623 TimTec1_005695 CN1C2=C(C(NC1=O)c3ccccc3)C(=O)N(C2)c4ccc(C)c(C)c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C20 compound treatment 49920.0 -2300.0 -0.13 45040.0 -5290.0 -0.4 -0.3777 -0.8944 1532646 TimTec1_005696 Cn1nccc1C(=O)NCCN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C21 compound treatment 51000.0 -1220.0 -0.07 51760.0 1430.0 0.11 0.0263 0.2033 1534811 TimTec1_005697 COc1c(O)ccc2c(OC)c3ccoc3nc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C22 compound treatment 47840.0 -4380.0 -0.25 41920.0 -8410.0 -0.64 -0.6299 -0.9188 3085660 TimTec1_005698 Cn1c2ccccc2c3nnc(SCc4ccc(F)cc4Cl)nc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C23 mock treatment 52600.0 376.0 0.02 49600.0 -733.0 -0.06 -0.0238 -0.3993 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 C24 mock treatment 55880.0 3660.0 0.21 56680.0 6350.0 0.48 0.4895 0.9323 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D01 compound treatment 37320.0 -14900.0 -0.86 32640.0 -17700.0 -1.34 -1.5576 -0.9775 3211624 TimTec1_005699 CC1CN=C(S1)N(C(=O)Nc2ccccc2)c3ccc(OC(F)(F)F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D02 compound treatment 47320.0 -4900.0 -0.28 48320.0 -2010.0 -0.15 -0.3086 -0.9573 3085662 TimTec1_005700 C(Sc1ncn[nH]1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D03 compound treatment 34880.0 -17300.0 -1.0 35320.0 -15000.0 -1.14 -1.5141 -0.9981 3211625 TimTec1_005701 Cc1ccc(NC(=O)C2CC(=O)N(Cc3ccccc3)/C(=N/c4ccccc4)/S2)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D04 compound treatment 32840.0 -19400.0 -1.12 34000.0 -16300.0 -1.24 -1.6683 -0.9989 3085663 TimTec1_005702 FC(F)(F)C(NCCc1c[nH]c2ccccc12)(NC(=O)c3ccccc3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D05 compound treatment 21080.0 -31100.0 -1.8 23160.0 -27200.0 -2.06 -2.7303 -0.9979 3211626 TimTec1_005703 CCC1(C)OC(=Nc2ccccc21)c3ccc(Br)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D06 compound treatment 4840.0 -47400.0 -2.75 7160.0 -43200.0 -3.27 -4.252 -0.9962 1384761 TimTec1_005704 Oc1ccc(NC2=C(C(=O)c3ccccc3C2=O)n4nnc5ccccc45)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D07 compound treatment 48120.0 -4100.0 -0.24 41760.0 -8570.0 -0.65 -0.627 -0.9072 1725838 TimTec1_005705 CSc1ccc(cc1)C2C3=C(CCCC3=O)Nc4ccc5ccccc5c24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D08 compound treatment 3840.0 -48400.0 -2.8 3840.0 -46500.0 -3.52 -4.4707 -0.9936 1630880 TimTec1_005706 Cn1c(nn(C2CC(=O)C3OCC2O3)c1=S)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D09 compound treatment 18160.0 -34100.0 -1.97 20040.0 -30300.0 -2.29 -3.0169 -0.9972 1339859 TimTec1_005707 COc1cc2ccccc2cc1C(=O)NCCC3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D10 compound treatment 38400.0 -13800.0 -0.8 36440.0 -13900.0 -1.05 -1.3099 -0.991 1488964 TimTec1_005708 CC(C)(C)c1ccc(cc1)C23OC(=O)C(C)(C)C3OC(=O)C2(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D11 compound treatment 46920.0 -5300.0 -0.31 42000.0 -8330.0 -0.63 -0.6633 -0.9454 1458934 TimTec1_005709 C1CN(CCN1)C2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D12 compound treatment 40120.0 -12100.0 -0.7 37760.0 -12600.0 -0.95 -1.1688 -0.9887 3211627 TimTec1_005710 O=C/1NC(=S)N\C1=C\c2cc3ccccc3nc2N4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D13 compound treatment 43320.0 -8900.0 -0.52 42800.0 -7530.0 -0.57 -0.7679 -0.9988 1617853 TimTec1_005711 Cc1cccc(C)c1NC(=O)C2(CCCC2)N(Cc3ccccc3)C(=O)c4ccc(cc4)n5cnnn5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D14 compound treatment 46160.0 -6060.0 -0.35 43320.0 -7010.0 -0.53 -0.6238 -0.9799 1422235 TimTec1_005712 Brc1ccc(CC2(CCc3ccncc3)C(=O)NC(=O)NC2=O)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D15 compound treatment 39080.0 -13100.0 -0.76 37200.0 -13100.0 -0.99 -1.2414 -0.9913 3211628 TimTec1_005713 CCN(CC)c1ccc(cc1)C2(NN(C(=C2C#N)N)c3ccccc3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D16 compound treatment 17920.0 -34300.0 -1.99 18120.0 -32200.0 -2.44 -3.1295 -0.9949 3085673 TimTec1_005714 C/C(=N\c1ccccc1)/C2=C(O)C=C(CC2c3ccco3)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D17 compound treatment 35360.0 -16900.0 -0.98 31960.0 -18400.0 -1.39 -1.6742 -0.9851 3211629 TimTec1_005715 Fc1ccc(CCN2C(=O)NC(=O)/C(=C\c3cccc4ccccc34)/C2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D18 compound treatment 26640.0 -25600.0 -1.48 27480.0 -22900.0 -1.73 -2.2713 -0.997 1524909 TimTec1_005716 COc1ccccc1c2nnc(o2)c3ccccc3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D19 compound treatment 1320.0 -50900.0 -2.95 1760.0 -48600.0 -3.68 -4.6852 -0.994 3211630 TimTec1_005717 COc1cccc(c1)c2cc(nc(SC3CC(=O)C4OCC3O4)n2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D20 compound treatment 44080.0 -8140.0 -0.47 44640.0 -5690.0 -0.43 -0.6383 -0.999 3085676 TimTec1_005718 FC(F)(F)c1cccc(c1)N2C(=O)CC(Cc3ccccc3)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D21 compound treatment 42040.0 -10200.0 -0.59 39000.0 -11300.0 -0.86 -1.0238 -0.9833 3211631 TimTec1_005719 CC1(C)OC(=O)C(=Cc2cccn2c3ccc(cc3)S(=O)(=O)N)C(=O)O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D22 compound treatment 43520.0 -8700.0 -0.5 44840.0 -5490.0 -0.42 -0.6506 -0.9954 3085679 TimTec1_005720 Cc1cccc2nc(=S)n(C(=O)c3ccc(F)cc3)n12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D23 mock treatment 57480.0 5260.0 0.3 46760.0 -3570.0 -0.27 0.0241 0.0592 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 D24 mock treatment 59920.0 7700.0 0.45 55800.0 5470.0 0.41 0.6079 0.9993 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E01 compound treatment 54640.0 2420.0 0.14 47880.0 -2450.0 -0.19 -0.0323 -0.1388 3211632 TimTec1_005721 Cc1cc(F)c(F)c(C(=O)n2ccnc2)c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E02 compound treatment 40200.0 -12000.0 -0.7 40960.0 -9370.0 -0.71 -0.9942 -1.0 1584802 TimTec1_005722 O=C(CSc1ccccc1)Nc2c(oc3ccccc23)C(=O)C4CC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E03 compound treatment 40480.0 -11700.0 -0.68 42440.0 -7890.0 -0.6 -0.9036 -0.9979 3211633 TimTec1_005723 COCc1cc(C)nc2sc(C(=O)OC)c(N)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E04 compound treatment 29280.0 -22900.0 -1.33 26480.0 -23900.0 -1.81 -2.2166 -0.9887 3211634 TimTec1_005724 CC(C)COC(=O)C1=C(C)Nc2cc(ccc2S1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E05 compound treatment 31160.0 -21100.0 -1.22 32200.0 -18100.0 -1.37 -1.8335 -0.9983 3085682 TimTec1_005725 Fc1ccc(COc2ccccc2/C=C\3/C(=O)NC(=O)N(CC=C)C3=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E06 compound treatment 22080.0 -30100.0 -1.75 23040.0 -27300.0 -2.07 -2.6957 -0.9965 3211635 TimTec1_005726 CN(C)c1ccc(/C=C\2/Oc3c(ccc(O)c3O)C2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E07 compound treatment 1920.0 -50300.0 -2.91 1600.0 -48700.0 -3.69 -4.6692 -0.9932 3211636 TimTec1_005727 CCn/1c(cs\c1=N\c2cc(OC)c(Cl)cc2OC)c3ccc(F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E08 compound treatment 26440.0 -25800.0 -1.49 30960.0 -19400.0 -1.47 -2.0932 -1.0 1668810 TimTec1_005728 N=C1OC23CCCCC3C(C#N)(C#N)C1(C#N)C(Cc4ccccc4)O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E09 compound treatment 33080.0 -19100.0 -1.11 31880.0 -18500.0 -1.4 -1.7719 -0.9935 1468867 TimTec1_005729 NS(=O)(=O)c1ccc(N=NN2CCCCCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E10 compound treatment 28960.0 -23300.0 -1.35 34320.0 -16000.0 -1.21 -1.8101 -0.9986 1221615 TimTec1_005730 CCc1ccc2cc(cn2c1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E11 compound treatment 33920.0 -18300.0 -1.06 26640.0 -23700.0 -1.79 -2.018 -0.9686 3211637 TimTec1_005731 CC1SC(N(C1=O)c2ccccc2)c3ccc(Br)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E12 compound treatment 48000.0 -4220.0 -0.24 47280.0 -3050.0 -0.23 -0.3364 -0.9996 1203111 TimTec1_005732 Cc1cc(C(=O)O)c(C#N)c(N)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E13 compound treatment 42320.0 -9900.0 -0.57 41520.0 -8810.0 -0.67 -0.8774 -0.9972 3211638 TimTec1_005733 NC(=NS(=O)(=O)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E14 compound treatment 38160.0 -14100.0 -0.81 34040.0 -16300.0 -1.23 -1.4482 -0.9798 3085709 TimTec1_005734 Cc1nc2ccccc2c(=O)n1c3ccc4OC(F)(F)Oc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E15 compound treatment 41160.0 -11100.0 -0.64 41880.0 -8450.0 -0.64 -0.9057 -1.0 3085711 TimTec1_005735 C/C(=C/C(=O)C1CC1)/C2CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E16 compound treatment 36960.0 -15300.0 -0.88 43000.0 -7330.0 -0.56 -1.0178 -0.9748 1198283 TimTec1_005736 CC(C(=O)Nc1ccc2OCCOc2c1)n3nnc(n3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E17 compound treatment 48480.0 -3740.0 -0.22 41440.0 -8890.0 -0.67 -0.6293 -0.8899 1200453 TimTec1_005737 CC1=C(C(C2=C(CC(C)(C)CC2=O)N1)c3ccc4OCOc4c3)C(=O)Nc5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E18 compound treatment 52800.0 576.0 0.03 44240.0 -6090.0 -0.46 -0.3025 -0.6542 1488913 TimTec1_005738 CCCc1cc(O)nc(SCC(=O)N2c3ccccc3Sc4ccccc24)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E19 compound treatment 37520.0 -14700.0 -0.85 37000.0 -13300.0 -1.01 -1.316 -0.9964 1378082 TimTec1_005739 CCOC(=O)C1(CCN(CC1)C(=O)c2ccccc2O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E20 compound treatment 48440.0 -3780.0 -0.22 43320.0 -7010.0 -0.53 -0.5304 -0.9235 1283200 TimTec1_005740 CC(C)N1C2OC(OC2N(C(C)C)S1(=O)=O)C3OC4C(O3)N(C(C)C)S(=O)(=O)N4C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E21 compound treatment 35600.0 -16600.0 -0.96 37480.0 -12900.0 -0.97 -1.369 -1.0 1315806 TimTec1_005741 CC(=O)Oc1ccc(C)cc1n2nc3ccccc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E22 compound treatment 45920.0 -6300.0 -0.37 47120.0 -3210.0 -0.24 -0.4302 -0.9805 3085715 TimTec1_005742 COc1ccccc1N/C=C/2\C(=O)NC(=O)N(C2=O)c3ccccc3OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E23 mock treatment 54360.0 2140.0 0.12 52720.0 2390.0 0.18 0.2153 0.983 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 E24 mock treatment 54960.0 2740.0 0.16 54000.0 3670.0 0.28 0.3084 0.9647 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F01 compound treatment 52520.0 296.0 0.02 56600.0 6270.0 0.47 0.3476 0.7322 1415787 TimTec1_005743 O=C(Cn1nnc(n1)c2ccc3OCOc3c2)N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F02 compound treatment 47960.0 -4260.0 -0.25 40840.0 -9490.0 -0.72 -0.6828 -0.8986 1291024 TimTec1_005744 Cc1[nH]c2ccccc2c1CCNC(=O)c3cc4cc(Br)ccc4oc3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F03 compound treatment 50960.0 -1260.0 -0.07 40200.0 -10100.0 -0.77 -0.5941 -0.7711 3085718 TimTec1_005745 FC(F)(F)c1nnc(S)n1/N=C/c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F04 compound treatment 48720.0 -3500.0 -0.2 42800.0 -7530.0 -0.57 -0.5467 -0.9033 1647381 TimTec1_005746 CC1CCN(CC1)S(=O)(=O)c2ccc(cc2)C(=O)NCc3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F05 compound treatment 51360.0 -864.0 -0.05 46400.0 -3930.0 -0.3 -0.2459 -0.8146 1416263 TimTec1_005747 Cc1c(NC(=O)C2CCCC2)c(=O)n(c3ccccc3)n1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F06 compound treatment 41920.0 -10300.0 -0.6 38000.0 -12300.0 -0.93 -1.0822 -0.9767 3211747 TimTec1_005748 Cc1cc(S)c2n(Cc3ccc(Cl)cc3Cl)nc[n+]2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F07 compound treatment 50000.0 -2220.0 -0.13 50000.0 -333.0 -0.03 -0.1089 -0.8296 1581088 TimTec1_005749 Fc1cccc(Cl)c1C2N3CCCCN23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F08 compound treatment 52120.0 -104.0 -0.01 45240.0 -5090.0 -0.39 -0.2768 -0.718 1406168 TimTec1_005750 COC(=O)c1ccc(CSc2nnc3c4ccccc4n(C)c3n2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F09 compound treatment 31680.0 -20500.0 -1.19 31320.0 -19000.0 -1.44 -1.8593 -0.9956 3211748 TimTec1_005751 Cc1cc(C)c(c(C)c1)n2nnnc2SCC(=O)Nc3nn(nc3C(=O)N)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F10 compound treatment 53560.0 1340.0 0.08 47360.0 -2970.0 -0.23 -0.1044 -0.4386 3087784 TimTec1_005752 CC1(NC(C2C1C(=O)N(C2=O)c3ccccc3)c4cc(Br)ccc4O)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F11 compound treatment 40600.0 -11600.0 -0.67 37560.0 -12800.0 -0.97 -1.1598 -0.9844 3211749 TimTec1_005753 N#CCC1(CC2CC3CC(C2)C1)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F12 compound treatment 17680.0 -34500.0 -2.0 19960.0 -30400.0 -2.3 -3.0409 -0.9976 1605647 TimTec1_005754 COc1ccc(cc1OC)C2C(Oc3ccc(Cl)cc3C)C(=O)N2c4ccc(C)c(C)c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F13 compound treatment 54720.0 2500.0 0.14 45480.0 -4850.0 -0.37 -0.1575 -0.3989 3087785 TimTec1_005755 C[S+](C)c1c(O)n(c2ccccc2F)c(=O)[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F14 compound treatment 36800.0 -15400.0 -0.89 33880.0 -16500.0 -1.25 -1.5125 -0.9867 1201797 TimTec1_005756 Fc1cc(Cl)c(cc1F)C(=O)NC2C3CC4CC(C3)CC2C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F15 compound treatment 45000.0 -7220.0 -0.42 45800.0 -4530.0 -0.34 -0.5385 -0.9951 1326307 TimTec1_005757 CC(Sc1nc(N)cc(N)n1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F16 compound treatment 21440.0 -30800.0 -1.78 18680.0 -31700.0 -2.4 -2.9553 -0.9894 1664927 TimTec1_005758 C=CCn1c2ccccc2c3nnc(SCc4ccc5nonc5c4)nc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F17 compound treatment 44200.0 -8020.0 -0.46 46400.0 -3930.0 -0.3 -0.5392 -0.9768 3087786 TimTec1_005759 CC(Nc1nc(F)cc(=O)[nH]1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F18 compound treatment 26320.0 -25900.0 -1.5 28880.0 -21500.0 -1.62 -2.2095 -0.9992 3211750 TimTec1_005760 CCOC(=O)/C=C/1\NC(C)(C)Cc2cc(OC)c(O)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F19 compound treatment 36840.0 -15400.0 -0.89 38360.0 -12000.0 -0.91 -1.2711 -1.0 3211751 TimTec1_005761 O=C(CSc1nnnn1c2ccccc2)NCCC3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F20 compound treatment 35960.0 -16300.0 -0.94 30440.0 -19900.0 -1.51 -1.731 -0.9745 3087787 TimTec1_005762 CC1SC2(CCCCC2)N(C1=O)c3cc(C)cc(C)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F21 compound treatment 25480.0 -26700.0 -1.55 21840.0 -28500.0 -2.16 -2.6207 -0.9868 3211752 TimTec1_005763 CC(=O)NC(NCCC1(CC2CC3CC(C2)C1)C3)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F22 compound treatment 43320.0 -8900.0 -0.52 47520.0 -2810.0 -0.21 -0.5153 -0.9234 1523330 TimTec1_005764 O=C(Oc1ccc(cc1)N(C(=O)c2ccccc2)S(=O)(=O)c3cccs3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F23 mock treatment 60440.0 8220.0 0.48 52800.0 2470.0 0.19 0.4687 0.9165 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 F24 mock treatment 54880.0 2660.0 0.15 56640.0 6310.0 0.48 0.4464 0.8899 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G01 compound treatment 51680.0 -544.0 -0.03 43240.0 -7090.0 -0.54 -0.4019 -0.7473 3087788 TimTec1_005765 Fc1ccccc1c2nnc3ccc(cn23)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G02 compound treatment 52360.0 136.0 0.01 44440.0 -5890.0 -0.45 -0.3098 -0.6945 3211753 TimTec1_005766 CN1C(=O)N(C)C2(N=C3SCC(=O)N3NC12c4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G03 compound treatment 45680.0 -6540.0 -0.38 44320.0 -6010.0 -0.46 -0.5899 -0.9959 1444799 TimTec1_005767 OC1=C(C(N(C1=O)c2cccnc2)c3ccccc3)C(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G04 compound treatment 41960.0 -10300.0 -0.59 40040.0 -10300.0 -0.78 -0.9714 -0.9911 1457617 TimTec1_005768 O=C(N1N=CCC1c2ccccc2)C3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G05 compound treatment 30280.0 -21900.0 -1.27 28440.0 -21900.0 -1.66 -2.0708 -0.9914 1406350 TimTec1_005769 Clc1ccccc1C(=O)Nc2ccc3nc(SCC(=O)N4CCc5ccccc45)sc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G06 compound treatment 36960.0 -15300.0 -0.88 42000.0 -8330.0 -0.63 -1.0713 -0.9863 1302719 TimTec1_005770 COC(=O)c1ccccc1NCNc2ccccc2C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G07 compound treatment 45680.0 -6540.0 -0.38 42320.0 -8010.0 -0.61 -0.6969 -0.9744 1261268 TimTec1_005771 CCCC(=C1C(=O)NC(=O)NC1=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G08 compound treatment 44640.0 -7580.0 -0.44 41240.0 -9090.0 -0.69 -0.7974 -0.9765 1028239 TimTec1_005772 S=c1sscc1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G09 compound treatment 48480.0 -3740.0 -0.22 43120.0 -7210.0 -0.55 -0.5394 -0.9182 3211754 TimTec1_005773 CCOC(=O)Cc1nc(C)cs1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G10 compound treatment 43560.0 -8660.0 -0.5 47080.0 -3250.0 -0.25 -0.529 -0.9462 1366551 TimTec1_005774 CCC1C(OC(=O)C(C)(C)C1=O)c2cccc(Br)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G11 compound treatment 44040.0 -8180.0 -0.47 43320.0 -7010.0 -0.53 -0.7106 -0.9984 3087789 TimTec1_005775 CC(=O)OC(C)(C)C#CCN1CCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G12 compound treatment 27760.0 -24500.0 -1.42 27560.0 -22800.0 -1.72 -2.2211 -0.9953 3211755 TimTec1_005776 O=C/1Nc2ccccc2\C1=C/3\NC(=S)N(C3=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G13 compound treatment 40680.0 -11500.0 -0.67 38560.0 -11800.0 -0.89 -1.103 -0.99 3087790 TimTec1_005777 CCOC1=NOC2C3CCC(C3)C21 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G14 compound treatment 44280.0 -7940.0 -0.46 38120.0 -12200.0 -0.92 -0.9791 -0.9481 3211756 TimTec1_005778 COc1ccc(cc1)C2OCC(C)(CO2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G15 compound treatment 45000.0 -7220.0 -0.42 42920.0 -7410.0 -0.56 -0.6927 -0.9896 3087791 TimTec1_005779 Nc1ccc(OC(F)(F)F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G16 compound treatment 36120.0 -16100.0 -0.93 32160.0 -18200.0 -1.38 -1.6324 -0.9821 1233416 TimTec1_005780 C(Sc1nnnn1c2ccc3OCOc3c2)C4CC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G17 compound treatment 45720.0 -6500.0 -0.38 42560.0 -7770.0 -0.59 -0.6825 -0.9768 1922264 TimTec1_005781 CC1(C)COC(O)(CC1=O)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G18 compound treatment 36640.0 -15600.0 -0.9 32120.0 -18200.0 -1.38 -1.6132 -0.9789 1589793 TimTec1_005782 CCc1ccc(cc1)C2Nc3ccccc3C(=O)N2c4ccc(cc4)N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G19 compound treatment 48560.0 -3660.0 -0.21 47240.0 -3090.0 -0.23 -0.3156 -0.9988 3087792 TimTec1_005783 CSC1=NC2C(N1)N(C)C(=O)N2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G20 compound treatment 14200.0 -38000.0 -2.2 16280.0 -34100.0 -2.58 -3.3804 -0.9969 1362774 TimTec1_005784 N=C1OC23CCCCC3C(C#N)(C#N)C1(C#N)C(O2)c4cccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G21 compound treatment 44880.0 -7340.0 -0.43 41760.0 -8570.0 -0.65 -0.7597 -0.9791 3087793 TimTec1_005785 O=C(Oc1ccc(cc1)c2cnc3ccccc3n2)/C=C/c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G22 compound treatment 23320.0 -28900.0 -1.67 24960.0 -25400.0 -1.92 -2.5422 -0.9977 1511555 TimTec1_005786 Clc1ccc2oc(=O)n(C(=O)NC3CCCCC3)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G23 mock treatment 46200.0 -6020.0 -0.35 46920.0 -3410.0 -0.26 -0.4294 -0.989 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 G24 mock treatment 51160.0 -1060.0 -0.06 49480.0 -853.0 -0.06 -0.0892 -0.9997 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H01 compound treatment 40000.0 -12200.0 -0.71 41800.0 -8530.0 -0.65 -0.9575 -0.9989 1788039 TimTec1_005787 Fc1ccccc1c2nnn(CC(=O)N3CCCCC3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H02 compound treatment 40760.0 -11500.0 -0.66 45080.0 -5250.0 -0.4 -0.7508 -0.9699 1578958 TimTec1_005788 COc1ccc(Cl)cc1S(=O)(=O)N2CCN(CC2)C3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H03 compound treatment 46880.0 -5340.0 -0.31 47400.0 -2930.0 -0.22 -0.3759 -0.9867 3087794 TimTec1_005789 COc1cc2CC(C)(C)N=C(NC(C)C(=O)O)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H04 compound treatment 51960.0 -264.0 -0.02 48680.0 -1650.0 -0.13 -0.0993 -0.7876 3087795 TimTec1_005790 NCCN1C(=O)S/C(=C/c2cccs2)/C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H05 compound treatment 49360.0 -2860.0 -0.17 42720.0 -7610.0 -0.58 -0.5248 -0.8752 1701075 TimTec1_005791 CCn1c(=N)n(CC(=O)c2cccs2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H06 compound treatment 44160.0 -8060.0 -0.47 39640.0 -10700.0 -0.81 -0.9027 -0.9659 1332043 TimTec1_005792 COC(=O)NC1CSCC1OC(=O)CCCN2C(=O)c3ccccc3C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H07 compound treatment 15360.0 -36900.0 -2.14 20520.0 -29800.0 -2.26 -3.1059 -0.9996 3087798 TimTec1_005793 COc1nsc(SC)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H08 compound treatment 52920.0 696.0 0.04 48520.0 -1810.0 -0.14 -0.0685 -0.4789 1015156 TimTec1_005794 COc1ccc(Cl)cc1NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H09 compound treatment 16080.0 -36100.0 -2.09 15760.0 -34600.0 -2.62 -3.3312 -0.9939 1397048 TimTec1_005795 COc1cc2ccccc2cc1C(=O)NC(C)Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H10 compound treatment 36280.0 -15900.0 -0.92 34040.0 -16300.0 -1.23 -1.5252 -0.9899 3087801 TimTec1_005796 CC1(C)CC(=O)C2=C(C1)N(C(=C(C#N)C2c3ccsc3)N)c4c(F)cccc4F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H11 compound treatment 44120.0 -8100.0 -0.47 45480.0 -4850.0 -0.37 -0.5917 -0.9926 1338227 TimTec1_005797 COc1ccc(NC(=O)c2cnn(c2NC(=O)c3ccccc3F)c4ccccc4)c(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H12 compound treatment 30160.0 -22100.0 -1.28 29680.0 -20700.0 -1.56 -2.0093 -0.995 1493728 TimTec1_005798 C1Oc2ccc(cc2O1)c3cc4ccccn4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H13 compound treatment 20000.0 -32200.0 -1.87 21280.0 -29100.0 -2.2 -2.8752 -0.9967 1440128 TimTec1_005799 COc1cc(NC(=O)NC2(CC2)c3ccccc3)c(OC)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H14 compound treatment 44320.0 -7900.0 -0.46 38360.0 -12000.0 -0.91 -0.9646 -0.95 1272978 TimTec1_005800 Cc1cc(NS(=O)(=O)c2ccccc2)cc(c1O)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H15 compound treatment 40320.0 -11900.0 -0.69 36720.0 -13600.0 -1.03 -1.2163 -0.9809 3211757 TimTec1_005801 Cc1cc(Cl)nc(NN)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H16 compound treatment 37960.0 -14300.0 -0.83 40920.0 -9410.0 -0.71 -1.0882 -0.9973 1520603 TimTec1_005802 Cn1c2ccc(Br)cc2c3nnc(SCc4ccc5nonc5c4)nc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H17 compound treatment 47760.0 -4460.0 -0.26 42040.0 -8290.0 -0.63 -0.6267 -0.9232 1486800 TimTec1_005803 CN(C)CP(=O)(O)CCn1c2ccccc2c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H18 compound treatment 46000.0 -6220.0 -0.36 44920.0 -5410.0 -0.41 -0.5447 -0.998 1194716 TimTec1_005804 OC(=O)C1Sc2c(sc(=O)n2Cc3ccccc3)C4C1C(=O)Oc5ccccc45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H19 compound treatment 46280.0 -5940.0 -0.34 43600.0 -6730.0 -0.51 -0.6039 -0.9818 1203354 TimTec1_005805 Nc1nnc(CCCn2c(=O)oc3ccccc23)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H20 compound treatment 20760.0 -31500.0 -1.82 17080.0 -33300.0 -2.52 -3.0688 -0.9875 3087859 TimTec1_005806 CC/N=C\1/S/C(=C/c2ccc(o2)c3ccc(F)cc3)/C(=O)N1CC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H21 compound treatment 37240.0 -15000.0 -0.87 35480.0 -14900.0 -1.12 -1.4088 -0.9918 1544104 TimTec1_005807 CN(C)c1ccc(cc1)C2OC(=O)C(C)(C)C(=O)C2(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H22 compound treatment 47280.0 -4940.0 -0.29 43880.0 -6450.0 -0.49 -0.5479 -0.9677 3211853 TimTec1_005808 CCCn1c2ccccc2c3nnc(SCC(=O)NCc4ccc5OCOc5c4)nc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H23 mock treatment 55400.0 3180.0 0.18 51560.0 1230.0 0.09 0.1958 0.9499 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 H24 mock treatment 49640.0 -2580.0 -0.15 52600.0 2270.0 0.17 0.0155 0.0681 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I01 compound treatment 17400.0 -34800.0 -2.02 21120.0 -29200.0 -2.21 -2.9902 -0.999 1315061 TimTec1_005809 CCOC1(C)N(Nc2ccccc2C(=O)CC)c3ccccc3C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I02 compound treatment 61240.0 9020.0 0.52 60880.0 10500.0 0.8 0.9339 0.9789 1011005 TimTec1_005810 OC(=O)CSc1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I03 compound treatment 43560.0 -8660.0 -0.5 42840.0 -7490.0 -0.57 -0.756 -0.9981 3211854 TimTec1_005811 CC1(C)OC(=O)N(Nc2ccccc2)C1(C)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I04 compound treatment 45840.0 -6380.0 -0.37 39680.0 -10700.0 -0.81 -0.8317 -0.9375 3087863 TimTec1_005812 Cc1c(Cl)cccc1NN 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I05 compound treatment 11200.0 -41000.0 -2.38 15440.0 -34900.0 -2.64 -3.5483 -0.9986 1462704 TimTec1_005813 CC(C)(C)NC(=O)CSc1nc2ccc(cc2s1)N3C(=O)c4ccccc4C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I06 compound treatment 50080.0 -2140.0 -0.12 39960.0 -10400.0 -0.79 -0.643 -0.8089 1663326 TimTec1_005814 Cc1cc(C)n2nc(nc2n1)S(=O)(=O)Nc3ccccc3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I07 compound treatment 27720.0 -24500.0 -1.42 31960.0 -18400.0 -1.39 -1.9872 -0.9999 3211855 TimTec1_005815 C1C/C(=C\c2nc3ccccc3[nH]2)/C(=C1)N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I08 compound treatment 53080.0 856.0 0.05 50920.0 588.0 0.04 0.0665 0.9985 1375813 TimTec1_005816 CN(C)c1ccc(cc1)C2N(Cc3ccccc3)C(=O)C(=C2C(=O)c4ccc(Cl)cc4)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I09 compound treatment 20280.0 -31900.0 -1.85 26920.0 -23400.0 -1.77 -2.5618 -0.9998 3087867 TimTec1_005817 COC(=O)c1c(CSC(=N)N)nc2n(Cc3ccccc3)c4ccccc4n12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I10 compound treatment 35120.0 -17100.0 -0.99 32080.0 -18300.0 -1.38 -1.6777 -0.9867 3211856 TimTec1_005818 CC1=C(OC(=O)c2ccccc2)C(C)(C)C(OC1=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I11 compound treatment 43360.0 -8860.0 -0.51 44360.0 -5970.0 -0.45 -0.6828 -0.998 3087868 TimTec1_005819 COC(=O)c1ccc(/N=C/2\SC(CC(=O)N2C)C(=O)O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I12 compound treatment 33120.0 -19100.0 -1.11 31520.0 -18800.0 -1.42 -1.7896 -0.9922 3211857 TimTec1_005820 COc1ccc(/C=N/c2nnc(c3ccccc3)c(n2)c4ccccc4)c(C(=O)O)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I13 compound treatment 23720.0 -28500.0 -1.65 23520.0 -26800.0 -2.03 -2.6029 -0.9948 3087871 TimTec1_005821 CC1CN(CN2C(=O)/C(=N\c3ccc4ccccc4c3)/c5ccccc25)CC(C)O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I14 compound treatment 31800.0 -20400.0 -1.18 28520.0 -21800.0 -1.65 -2.0042 -0.9867 1190190 TimTec1_005822 CC(=O)OC1c2ccccc2NC(c3ccccc3)C1(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I15 compound treatment 3000.0 -49200.0 -2.85 3400.0 -46900.0 -3.55 -4.5286 -0.9941 1442650 TimTec1_005823 COC(=O)C1=C(C)NC(=C(C#N)C1c2cccs2)SCC(=O)C3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I16 compound treatment 46480.0 -5740.0 -0.33 42960.0 -7370.0 -0.56 -0.6299 -0.9695 3087873 TimTec1_005824 SC1=C(C#N)C2(CCCCC2)C(C(=N)N1)c3nc(cs3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I17 compound treatment 46640.0 -5580.0 -0.32 47960.0 -2370.0 -0.18 -0.3557 -0.9614 1201213 TimTec1_005825 OC(=O)c1ccc(N=NN2CCCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I18 compound treatment 26600.0 -25600.0 -1.48 26000.0 -24300.0 -1.84 -2.3521 -0.9943 3211858 TimTec1_005826 CSc1ccc(cc1)S(=O)(=O)Nc2ccc(N3CCOCC3)c(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I19 compound treatment 8840.0 -43400.0 -2.51 14360.0 -36000.0 -2.72 -3.7027 -0.9992 1656330 TimTec1_005827 CC(C)(CN1CCN(CC1)C(c2ccccc2)c3ccccc3)NS(=O)(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I20 compound treatment 18360.0 -33900.0 -1.96 24160.0 -26200.0 -1.98 -2.7882 -1.0 1594685 TimTec1_005828 CC1C(C#N)(C#N)C2(C#N)C(OC1(C)OC2=N)c3ccncc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I21 compound treatment 41040.0 -11200.0 -0.65 38640.0 -11700.0 -0.89 -1.084 -0.9883 3211859 TimTec1_005829 O=C/1N(CN2CCN(CC2)c3ccccc3)c4ccccc4\C1=N\c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I22 compound treatment 46560.0 -5660.0 -0.33 43680.0 -6650.0 -0.5 -0.5881 -0.9785 1426903 TimTec1_005830 Nc1c(C#N)c(c(C#N)c2nc3ccccc3n12)c4cccc(O)c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I23 mock treatment 52200.0 -23.8 0.0 52000.0 1670.0 0.13 0.0883 0.6994 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 I24 mock treatment 43840.0 -8380.0 -0.49 51880.0 1550.0 0.12 -0.2606 -0.5216 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J01 compound treatment 46960.0 -5260.0 -0.3 47280.0 -3050.0 -0.23 -0.379 -0.9906 1380440 TimTec1_005831 CC(C)(CO)NC1(CC2CC3CC(C2)C1)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J02 compound treatment 36760.0 -15500.0 -0.9 28360.0 -22000.0 -1.66 -1.8096 -0.9579 1328534 TimTec1_005832 Clc1ccc(Cl)c(c1)S(=O)(=O)NCCC2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J03 compound treatment 31440.0 -20800.0 -1.2 34640.0 -15700.0 -1.19 -1.6914 -1.0 3211860 TimTec1_005833 FC(F)(F)C1=CC(=NCCN1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J04 compound treatment 33000.0 -19200.0 -1.11 39240.0 -11100.0 -0.84 -1.3813 -0.9903 1159735 TimTec1_005834 CN(C)P1(=O)Nc2ccccc2S1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J05 compound treatment 43440.0 -8780.0 -0.51 41800.0 -8530.0 -0.65 -0.8165 -0.993 1421447 TimTec1_005835 CC(C)(O)C1(C)NCCc2ccccc21 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J06 compound treatment 35960.0 -16300.0 -0.94 37200.0 -13100.0 -0.99 -1.3692 -0.9996 1178221 TimTec1_005836 CC1CC2(CC(C)(C)C1)NN(C(=S)N2)c3ccc(C)c(C)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J07 compound treatment 42160.0 -10100.0 -0.58 46160.0 -4170.0 -0.32 -0.6356 -0.9585 1709992 TimTec1_005837 CC1(C)CC(CC(C)(C)N1)NCc2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J08 compound treatment 42880.0 -9340.0 -0.54 41400.0 -8930.0 -0.68 -0.8609 -0.9939 1603180 TimTec1_005838 O=C(NC1CCCCC1)C2CC(=O)OC32CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J09 compound treatment 30880.0 -21300.0 -1.24 27000.0 -23300.0 -1.77 -2.1233 -0.9848 1526847 TimTec1_005839 Cc1ccc2c3C(C4=C(CCCC4=O)Nc3ccc2n1)c5ccccc5C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J10 compound treatment 9960.0 -42300.0 -2.45 11760.0 -38600.0 -2.92 -3.796 -0.9962 3211861 TimTec1_005840 CCc1nc2sc(C(=O)Nc3ccc(OC(F)(F)F)cc3)c(N)c2cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J11 compound treatment 35280.0 -16900.0 -0.98 32440.0 -17900.0 -1.35 -1.6518 -0.9875 1564041 TimTec1_005841 CCN(C(=O)Cn1nnc(n1)c2ccc3OCOc3c2)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J12 compound treatment 38840.0 -13400.0 -0.78 31720.0 -18600.0 -1.41 -1.5445 -0.9604 3087925 TimTec1_005842 FC(F)(F)c1nnc2SCC(=Nn12)c3ccc(Cl)cc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J13 compound treatment 44240.0 -7980.0 -0.46 41120.0 -9210.0 -0.7 -0.8202 -0.9801 3211862 TimTec1_005843 CCN1C(=O)C2NN=C(C2C1=O)C(=O)c3nc(Cl)ccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J14 compound treatment 31720.0 -20500.0 -1.19 33240.0 -17100.0 -1.29 -1.7549 -0.9991 1209557 TimTec1_005844 COc1ccc(cc1)C(=O)Nc2cc(C)c(O)c(c2C)S(=O)(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J15 compound treatment 30840.0 -21400.0 -1.24 26360.0 -24000.0 -1.81 -2.1592 -0.9827 3211863 TimTec1_005845 Sc1nc(SCCOc2ccccc2)nc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J16 compound treatment 27800.0 -24400.0 -1.42 29920.0 -20400.0 -1.55 -2.0932 -0.999 3087928 TimTec1_005846 CC(C)(C)C(=O)/C=C/1\NCCN\C1=C/C(=O)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J17 compound treatment 45920.0 -6300.0 -0.37 42200.0 -8130.0 -0.62 -0.6935 -0.9689 1272266 TimTec1_005847 OC(=O)C(Cc1ccco1)P(=O)(O)CN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J18 compound treatment 28760.0 -23500.0 -1.36 30360.0 -20000.0 -1.51 -2.0303 -0.9986 1688384 TimTec1_005848 O=C(Nc1ccccc1)c2cccc(c2)S(=O)(=O)NCC3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J19 compound treatment 28840.0 -23400.0 -1.35 30240.0 -20100.0 -1.52 -2.0334 -0.9983 1696945 TimTec1_005849 COc1cccc(c1)C(=O)Nc2cccc(C)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J20 compound treatment 27880.0 -24300.0 -1.41 30600.0 -19700.0 -1.49 -2.0535 -0.9996 3087931 TimTec1_005850 Cc1cccn2cc(cc12)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J21 compound treatment 42720.0 -9500.0 -0.55 44000.0 -6330.0 -0.48 -0.7283 -0.9976 1142933 TimTec1_005851 Cc1ccc(cc1)C(=O)C2OC(=O)C(C)(C)C(=O)C2(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J22 compound treatment 34760.0 -17500.0 -1.01 3280.0 -47100.0 -3.56 -3.2339 -0.8734 3211864 TimTec1_005852 COc1cccc2cc(C(=O)NCCc3c(C)[nH]c4ccc(OC(F)(F)F)cc34)c(=O)oc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J23 mock treatment 52560.0 336.0 0.02 50960.0 628.0 0.05 0.0474 0.9225 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 J24 mock treatment 46600.0 -5620.0 -0.33 46680.0 -3650.0 -0.28 -0.4259 -0.9967 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K01 compound treatment 28960.0 -23300.0 -1.35 26400.0 -23900.0 -1.81 -2.234 -0.9894 1683560 TimTec1_005853 CCn1c(nc2ccccc12)C(O)c3cc(c(O)c(c3)C(C)(C)C)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K02 compound treatment 42680.0 -9540.0 -0.55 41400.0 -8930.0 -0.68 -0.8691 -0.995 3088026 TimTec1_005854 O=C1CSC2=NCN(CN12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K03 compound treatment 19680.0 -32500.0 -1.89 23320.0 -27000.0 -2.04 -2.7791 -0.9992 3087964 TimTec1_005855 CCOC(=O)C1=C(C)NC(=NC1c2ccc(OC(=O)C)c(OC)c2)SC(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K04 compound treatment 37520.0 -14700.0 -0.85 34560.0 -15800.0 -1.19 -1.4466 -0.9863 3087966 TimTec1_005856 CC(=O)NCCOc1cccc2cccnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K05 compound treatment 2440.0 -49800.0 -2.88 4040.0 -46300.0 -3.5 -4.5173 -0.9953 1264565 TimTec1_005857 Cn1c(SCc2ccc(F)c3ccccc23)nc4ccccc4c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K06 compound treatment 40760.0 -11500.0 -0.66 37800.0 -12500.0 -0.95 -1.1404 -0.9848 3211865 TimTec1_005858 Clc1ccc(/N=C/2\C(=O)N(CN3CCc4ccccc4C3)c5ccccc25)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K07 compound treatment 41960.0 -10300.0 -0.59 36160.0 -14200.0 -1.07 -1.1791 -0.9613 1638757 TimTec1_005859 CCN(CC)P1(=O)COc2ccccc2OC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K08 compound treatment 38400.0 -13800.0 -0.8 27840.0 -22500.0 -1.7 -1.7702 -0.9408 3211945 TimTec1_005860 CCC1CCC2(CC1)SCC(=O)N2c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K09 compound treatment 24920.0 -27300.0 -1.58 23960.0 -26400.0 -2.0 -2.5301 -0.9934 1385466 TimTec1_005861 COc1ccc(cc1)N(C)C(=O)C2COc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K10 compound treatment 23320.0 -28900.0 -1.67 26920.0 -23400.0 -1.77 -2.4373 -0.9996 1301245 TimTec1_005862 Cc1ccc(NS(=O)(=O)c2c(C)ccc3nsnc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K11 compound treatment 35200.0 -17000.0 -0.99 36480.0 -13900.0 -1.05 -1.4389 -0.9995 3087971 TimTec1_005863 CN(C)/C=N\c1ccc2nonc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K12 compound treatment 29480.0 -22700.0 -1.32 33240.0 -17100.0 -1.29 -1.8466 -1.0 1432844 TimTec1_005864 CCOC(=O)c1c(CN2CCCC2)n(C)c3cc(Br)c(OC)cc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K13 compound treatment 33080.0 -19100.0 -1.11 31640.0 -18700.0 -1.41 -1.7848 -0.9927 3211946 TimTec1_005865 CSC1=NC2(CC(Oc3cc(O)ccc32)c4ccccc4)CC(C)(C)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K14 compound treatment 30160.0 -22100.0 -1.28 30080.0 -20300.0 -1.53 -1.9879 -0.9959 3087973 TimTec1_005866 CC(=O)N1C(=O)/C(=C\c2cccnc2)/NC1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K15 compound treatment 19120.0 -33100.0 -1.92 18840.0 -31500.0 -2.38 -3.0418 -0.9942 1685221 TimTec1_005867 CCOC(=O)c1c(NC(=O)CSc2nccn2C)sc3CC(C)CCc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K16 compound treatment 17120.0 -35100.0 -2.03 21880.0 -28500.0 -2.15 -2.961 -0.9996 3087975 TimTec1_005868 Oc1ccccc1c2cc(nn2Cc3ccc(Cl)cc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K17 compound treatment 28560.0 -23700.0 -1.37 24960.0 -25400.0 -1.92 -2.3275 -0.9863 1551420 TimTec1_005869 COC(=O)c1ccc(N=NN2CCCCCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K18 compound treatment 42200.0 -10000.0 -0.58 38240.0 -12100.0 -0.92 -1.0579 -0.9759 1545682 TimTec1_005870 COc1ccc(cc1)C2CC(=O)Oc3ccc(cc23)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K19 compound treatment 23760.0 -28500.0 -1.65 17000.0 -33300.0 -2.52 -2.9502 -0.9788 1253632 TimTec1_005871 O=C(N(Cc1ccccc1)c2ccccn2)C3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K20 compound treatment 35120.0 -17100.0 -0.99 32240.0 -18100.0 -1.37 -1.6691 -0.9874 3211947 TimTec1_005872 COc1nc(OC)nc(n1)n2cnc(NC(=O)Nc3cccc(Cl)c3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K21 compound treatment 40040.0 -12200.0 -0.71 34400.0 -15900.0 -1.21 -1.3519 -0.9675 1118061 TimTec1_005873 Sc1nc2-c3ccccc3CC(C4CCCCC4)c2c(=O)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K22 compound treatment 33280.0 -18900.0 -1.1 27720.0 -22600.0 -1.71 -1.9864 -0.9769 3211948 TimTec1_005874 CCC(C#N)C1(CC2CC3CC(C2)C1)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K23 mock treatment 42880.0 -9340.0 -0.54 43000.0 -7330.0 -0.56 -0.7753 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 K24 mock treatment 41720.0 -10500.0 -0.61 44240.0 -6090.0 -0.46 -0.7564 -0.9906 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L01 compound treatment 46480.0 -5740.0 -0.33 37680.0 -12700.0 -0.96 -0.9125 -0.9 3087980 TimTec1_005875 COC(=O)c1ccc(cc1)C2OCC(C)(C)CO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L02 compound treatment 34120.0 -18100.0 -1.05 32160.0 -18200.0 -1.38 -1.7143 -0.991 1135137 TimTec1_005876 CCOc1ccc(CCNS(=O)(=O)c2c(C)cc(C)cc2C)cc1OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L03 compound treatment 38920.0 -13300.0 -0.77 41560.0 -8770.0 -0.66 -1.0146 -0.9972 3211949 TimTec1_005877 COc1ccc(CN/2C(=O)CC(S\C2=N/c3ccccc3)C(=O)N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L04 compound treatment 15200.0 -37000.0 -2.15 21720.0 -28600.0 -2.17 -3.0482 -1.0 1515423 TimTec1_005878 CCOc1nc(Cl)nc(n1)N2CCCCC2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L05 compound treatment 44680.0 -7540.0 -0.44 42520.0 -7810.0 -0.59 -0.7272 -0.9889 3088028 TimTec1_005879 COc1ccc(cc1)C(=O)NC(N2CCCCC2c3cccnc3)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L06 compound treatment 30040.0 -22200.0 -1.29 34840.0 -15500.0 -1.17 -1.738 -0.999 1732675 TimTec1_005880 CCOc1ccc(CC(=O)Nc2ccccc2)cc1OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L07 compound treatment 29560.0 -22700.0 -1.31 28680.0 -21700.0 -1.64 -2.0874 -0.994 1230635 TimTec1_005881 Cc1ccc2c3C(C4=C(CCCC4=O)Nc3ccc2n1)c5ccc(O)cc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L08 compound treatment 43440.0 -8780.0 -0.51 43000.0 -7330.0 -0.56 -0.7523 -0.9991 1233176 TimTec1_005882 CCNC(=O)C1CC(=O)OC21CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L09 compound treatment 45560.0 -6660.0 -0.39 38680.0 -11700.0 -0.88 -0.8967 -0.9313 1157682 TimTec1_005883 COCc1cc(C)nc(SCC(=O)N2CCCCC2)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L10 compound treatment 46760.0 -5460.0 -0.32 39720.0 -10600.0 -0.8 -0.7919 -0.9171 3088032 TimTec1_005884 CC(=O)ON1C(C)(C)C=C(C(=O)N)C1(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L11 compound treatment 31600.0 -20600.0 -1.19 35240.0 -15100.0 -1.14 -1.6527 -0.9997 3211950 TimTec1_005885 COc1ccccc1n2c(S)nnc2Cc3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L12 compound treatment 34720.0 -17500.0 -1.01 37040.0 -13300.0 -1.01 -1.4286 -1.0 1274328 TimTec1_005886 COc1ccccc1C2C3=C(CCCC3=O)Nc4ccc5ncccc5c24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L13 compound treatment 13920.0 -38300.0 -2.22 17360.0 -33000.0 -2.5 -3.3341 -0.9983 3211951 TimTec1_005887 COC(=O)C1=CN(CC2(CC3CC4CC(C3)C2)C4)C=C(C1c5ccc(F)cc5)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L14 compound treatment 40600.0 -11600.0 -0.67 32480.0 -17900.0 -1.35 -1.4317 -0.9483 1513069 TimTec1_005888 CC(C)c1c(NC(=O)c2ccc(Cl)cc2)cc(C)c(O)c1S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L15 compound treatment 15520.0 -36700.0 -2.13 12520.0 -37800.0 -2.86 -3.5276 -0.9893 1273520 TimTec1_005889 CCn1c(SCCn2c(=S)n(C)c3ccccc23)nc4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L16 compound treatment 46560.0 -5660.0 -0.33 42280.0 -8050.0 -0.61 -0.663 -0.9578 1715744 TimTec1_005890 C(N1CCCC1)c2cc3ccccc3c4COCc42 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L17 compound treatment 11320.0 -40900.0 -2.37 9400.0 -40900.0 -3.1 -3.8666 -0.9912 1402014 TimTec1_005891 Cc1nc2cccc(C(=O)Oc3ccc(cc3)C(C)(C)C)c2o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L18 compound treatment 38400.0 -13800.0 -0.8 36480.0 -13900.0 -1.05 -1.3078 -0.9912 1594146 TimTec1_005892 O=C(Nc1ccccc1)c2cccc(c2)S(=O)(=O)NCCC3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L19 compound treatment 50760.0 -1460.0 -0.08 39560.0 -10800.0 -0.82 -0.6366 -0.7765 3088038 TimTec1_005893 CCc1nnc(NC(=O)CSc2nnc(c3cccs3)n2CC=C)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L20 compound treatment 37800.0 -14400.0 -0.84 32000.0 -18300.0 -1.39 -1.5721 -0.9705 3211952 TimTec1_005894 CCN(CC)c1ccc(C=C2C(=O)OC(OC2=O)c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L21 compound treatment 50400.0 -1820.0 -0.11 43560.0 -6770.0 -0.51 -0.4372 -0.8353 3088039 TimTec1_005895 OC(=O)/C(=C/C(=O)c1ccccc1)/Nc2ccc(OC(F)(F)F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L22 compound treatment 51400.0 -824.0 -0.05 43920.0 -6410.0 -0.49 -0.377 -0.7729 1788194 TimTec1_005896 CCOC(=O)c1c(C)c(NC(=O)C)c(C)n1C(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L23 mock treatment 46600.0 -5620.0 -0.33 47400.0 -2930.0 -0.22 -0.3874 -0.9825 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 L24 mock treatment 44920.0 -7300.0 -0.42 48440.0 -1890.0 -0.14 -0.4005 -0.8965 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M01 compound treatment 21200.0 -31000.0 -1.8 19960.0 -30400.0 -2.3 -2.8966 -0.9926 1430182 TimTec1_005897 Cc1cc(NC(=O)c2cccc(c2)S(=O)(=O)Nc3ccc(C)cc3)no1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M02 compound treatment 45920.0 -6300.0 -0.37 47200.0 -3130.0 -0.24 -0.4259 -0.9781 1516860 TimTec1_005898 CCN1C2OC3OC4C(OC3OC2N(CC)S1(=O)=O)N(CC)S(=O)(=O)N4CC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M03 compound treatment 42200.0 -10000.0 -0.58 39520.0 -10800.0 -0.82 -0.9894 -0.9859 1315988 TimTec1_005899 Clc1ccccc1NCn2nc(c3ccccc3)n(CC=C)c2=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M04 compound treatment 35760.0 -16500.0 -0.95 33200.0 -17100.0 -1.3 -1.5915 -0.9886 3088042 TimTec1_005900 CCC(=O)NC(Nc1sc(C)c(CC)c1C#N)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M05 compound treatment 45280.0 -6940.0 -0.4 42640.0 -7690.0 -0.58 -0.6962 -0.9837 3211953 TimTec1_005901 CC(C)C1C(=C(N)Oc2n[nH]c(C)c12)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M06 compound treatment 37720.0 -14500.0 -0.84 36160.0 -14200.0 -1.07 -1.3528 -0.9927 1171314 TimTec1_005902 COc1ccc(OC)c(CNc2ccc3n(C)c(C)nc3c2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M07 compound treatment 28440.0 -23800.0 -1.38 26960.0 -23400.0 -1.77 -2.2254 -0.9924 3088045 TimTec1_005903 CCOC(=O)C1=C(C)NC(=NC1c2ccccc2)SCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M08 compound treatment 48880.0 -3340.0 -0.19 45000.0 -5330.0 -0.4 -0.4224 -0.9434 1705094 TimTec1_005904 OC(=O)Cc1c(Sc2ccccc2)c3ccccc3n1Cc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M09 compound treatment 25600.0 -26600.0 -1.54 27680.0 -22700.0 -1.71 -2.3032 -0.9986 3211954 TimTec1_005905 CN(C)c1ccc(/C=C/2\C(=O)N(N=C2C(=O)Nc3ccccc3)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M10 compound treatment 22280.0 -29900.0 -1.73 22120.0 -28200.0 -2.14 -2.7368 -0.9947 1621165 TimTec1_005906 O1c2ccccc2N=C(c3ccccc3)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M11 compound treatment 40320.0 -11900.0 -0.69 34560.0 -15800.0 -1.19 -1.3319 -0.966 1640716 TimTec1_005907 CCN(CC)C(=O)c1cn(nc1C2(CC3CC4CC(C3)C2)C4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M12 compound treatment 43240.0 -8980.0 -0.52 33720.0 -16600.0 -1.26 -1.2572 -0.9238 3211955 TimTec1_005908 OC(=O)C1CC(=O)N(CCc2ccccc2)/C(=N/CCc3ccccc3)/S1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M13 compound treatment 30600.0 -21600.0 -1.25 22000.0 -28300.0 -2.14 -2.4024 -0.9672 3088114 TimTec1_005909 CCCN1C(=O)/C(=C/C=C\2/Sc3ccccc3N2CCO)/SC1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M14 compound treatment 32000.0 -20200.0 -1.17 23600.0 -26700.0 -2.02 -2.2594 -0.9663 1416853 TimTec1_005910 CCCCC(=O)Nc1ccc(cc1)c2csc(n2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M15 compound treatment 27280.0 -24900.0 -1.45 22760.0 -27600.0 -2.09 -2.4977 -0.9839 3088116 TimTec1_005911 FC(F)(F)c1cccc(/N=C/2\C(=O)N(CN3CCc4ccccc4C3)c5ccccc25)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M16 compound treatment 33320.0 -18900.0 -1.1 28880.0 -21500.0 -1.62 -1.9227 -0.9816 1117685 TimTec1_005912 CN(C)c1ccc(cc1)C2OC(COc3ccccc3)CN(O2)C(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M17 compound treatment 31680.0 -20500.0 -1.19 28080.0 -22300.0 -1.68 -2.0327 -0.9855 1411622 TimTec1_005913 O=C(N(c1ccccc1)c2ccccc2)c3ccccc3C(=O)N4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M18 compound treatment 43360.0 -8860.0 -0.51 40640.0 -9690.0 -0.73 -0.8819 -0.9848 1119974 TimTec1_005914 COc1ccc(cc1)c2nc(SCc3ccccc3C#N)[nH]c(=O)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M19 compound treatment 29080.0 -23100.0 -1.34 26760.0 -23600.0 -1.78 -2.2099 -0.9901 1518985 TimTec1_005915 CC(C1C(=C(N)Oc2c1c(=O)oc3ccccc23)C#N)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M20 compound treatment 40760.0 -11500.0 -0.66 43960.0 -6370.0 -0.48 -0.8107 -0.9877 3088119 TimTec1_005916 FC(F)(F)c1ccc(cc1)C(=O)Nc2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M21 compound treatment 43680.0 -8540.0 -0.5 44280.0 -6050.0 -0.46 -0.674 -0.9993 1232476 TimTec1_005917 CC1CN(C(=O)C)c2ccccc2NC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M22 compound treatment 40680.0 -11500.0 -0.67 37840.0 -12500.0 -0.95 -1.1416 -0.9856 1452888 TimTec1_005918 O=C1N(C(=O)c2cccc3cccc1c23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M23 mock treatment 54280.0 2060.0 0.12 46760.0 -3570.0 -0.27 -0.107 -0.362 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 M24 mock treatment 51560.0 -664.0 -0.04 50280.0 -52.5 0.0 -0.03 -0.776 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N01 compound treatment 27640.0 -24600.0 -1.42 17680.0 -32700.0 -2.47 -2.7548 -0.9657 1241281 TimTec1_005919 COc1cc(NC(=O)c2cc3ccccc3cc2OCC(=O)NC(C)(C)C)c(OC)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N02 compound treatment 42440.0 -9780.0 -0.57 43080.0 -7250.0 -0.55 -0.789 -0.9999 3088122 TimTec1_005920 CCn/1cccc\c1=N/P2(=S)OCCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N03 compound treatment 50920.0 -1300.0 -0.08 43840.0 -6490.0 -0.49 -0.4009 -0.8063 1595949 TimTec1_005921 OC1=C(C(N(CCc2ccccc2)C1=O)c3ccccc3)C(=O)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N04 compound treatment 37200.0 -15000.0 -0.87 37800.0 -12500.0 -0.95 -1.2863 -0.9991 1572095 TimTec1_005922 COCc1cc(C)nc2[nH]nc(N)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N05 compound treatment 27720.0 -24500.0 -1.42 36920.0 -13400.0 -1.02 -1.7218 -0.9865 3212011 TimTec1_005923 O=C(NCCOc1ccccc1)/C=C/c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N06 compound treatment 44360.0 -7860.0 -0.46 42440.0 -7890.0 -0.6 -0.7446 -0.9911 3212012 TimTec1_005924 CCOC(=O)c1cn(nc1N)C2CC(=O)C3OCC2O3.CCOC(=O)c1cn(nc1N)C2CC(O)(O)C3OCC2O3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N07 compound treatment 45320.0 -6900.0 -0.4 48280.0 -2050.0 -0.16 -0.3927 -0.9152 3088126 TimTec1_005925 NC[C@@H]1CCCN2CCCC[C@H]12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N08 compound treatment 41920.0 -10300.0 -0.6 41600.0 -8730.0 -0.66 -0.8895 -0.9987 1354761 TimTec1_005926 CCC(C)NCc1ccc(o1)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N09 compound treatment 6280.0 -45900.0 -2.66 8080.0 -42300.0 -3.2 -4.1438 -0.9958 1518220 TimTec1_005927 CSC1=NC(=C(C(=O)Nc2ccccc2)C3(CCCCC3)C1C(=O)N)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N10 compound treatment 1200.0 -51000.0 -2.96 2000.0 -48300.0 -3.66 -4.6773 -0.9944 3212013 TimTec1_005928 OC1(O)CC(C2COC1O2)n3nc(c4ccco4)n(CC=C)c3=S.C=CCn1c(nn(C2CC(=O)C3OCC2O3)c1=S)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N11 compound treatment 26760.0 -25500.0 -1.48 21200.0 -29100.0 -2.21 -2.6025 -0.9809 3088130 TimTec1_005929 Cc1cc2CC(C)(C)N/C(=C/C(=O)N)/c2cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N12 compound treatment 17280.0 -34900.0 -2.02 17360.0 -33000.0 -2.5 -3.1964 -0.9946 1138138 TimTec1_005930 CCOC(=O)c1[nH]c(C)c(CNc2ccccc2)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N13 compound treatment 34680.0 -17500.0 -1.02 32280.0 -18100.0 -1.37 -1.685 -0.9894 1675612 TimTec1_005931 COc1nonc1n2nnc(C(=O)c3ccccc3)c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N14 compound treatment 40920.0 -11300.0 -0.65 33120.0 -17200.0 -1.3 -1.3844 -0.9494 1140939 TimTec1_005932 CCCc1c(C)[nH]c2nc3ccccc3n2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N15 compound treatment 32880.0 -19300.0 -1.12 32920.0 -17400.0 -1.32 -1.7245 -0.9967 3088132 TimTec1_005933 Clc1ccccc1c2nnc3cccc(Cl)n23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N16 compound treatment 14280.0 -37900.0 -2.2 11000.0 -39300.0 -2.98 -3.6597 -0.9889 1219341 TimTec1_005934 CCN(C(=O)c1c(C)c(Cl)c(C)nc1Oc2ccc(F)cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N17 compound treatment 30960.0 -21300.0 -1.23 25200.0 -25100.0 -1.9 -2.2163 -0.9779 1518508 TimTec1_005935 CC(=O)N(CC1(CC2CC3CC(C2)C1)C3)C4CC(=O)N(C4=O)c5cccc(Cl)c5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N18 compound treatment 44440.0 -7780.0 -0.45 39360.0 -11000.0 -0.83 -0.9062 -0.9588 3088204 TimTec1_005936 Cn1nc(cc1Cl)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N19 compound treatment 52720.0 496.0 0.03 48720.0 -1610.0 -0.12 -0.066 -0.5261 3088206 TimTec1_005937 Cc1ccc(N/C(=C/C(=O)c2ccccc2)/C(=O)O)cc1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N20 compound treatment 24400.0 -27800.0 -1.61 23000.0 -27300.0 -2.07 -2.6028 -0.9924 3088207 TimTec1_005938 CC(C)(C)C1(C)OC(=O)C(=Cc2ccc(Br)o2)C(=O)O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N21 compound treatment 37960.0 -14300.0 -0.83 34000.0 -16300.0 -1.24 -1.4585 -0.9808 3212014 TimTec1_005939 COCCN1C=C(C(C(=C1)C(=O)OC)c2cccs2)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N22 compound treatment 39960.0 -12300.0 -0.71 37000.0 -13300.0 -1.01 -1.216 -0.9853 3212015 TimTec1_005940 CN/1CCC\C1=C\C=C\2/SC(=S)NC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N23 mock treatment 54360.0 2140.0 0.12 46280.0 -4050.0 -0.31 -0.1294 -0.3912 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 N24 mock treatment 43880.0 -8340.0 -0.48 52960.0 2630.0 0.2 -0.2012 -0.3849 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O01 compound treatment 33800.0 -18400.0 -1.07 42960.0 -7370.0 -0.56 -1.1494 -0.9542 1199249 TimTec1_005941 CCCn1c2ccccc2c3nnc(SCC(=O)NC(C)c4ccccc4)nc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O02 compound treatment 53560.0 1340.0 0.08 52880.0 2550.0 0.19 0.1911 0.9196 1786664 TimTec1_005942 CC(C)c1cc(=O)n2nc(N)[nH]c2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O03 compound treatment 40840.0 -11400.0 -0.66 39720.0 -10600.0 -0.8 -1.0344 -0.9952 3212016 TimTec1_005943 Fc1ccccc1COc2ccccc2/C=C\3/SC(=N)NC3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O04 compound treatment 53480.0 1260.0 0.07 44800.0 -5530.0 -0.42 -0.2447 -0.5756 1724360 TimTec1_005944 c1c(nc2nc(c3ccccc3)c(nn12)c4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O05 compound treatment 24040.0 -28200.0 -1.63 22120.0 -28200.0 -2.14 -2.6647 -0.9912 3088212 TimTec1_005945 O=C(CSC1=NC(CC(=O)N1)c2ccccc2)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O06 compound treatment 41480.0 -10700.0 -0.62 40960.0 -9370.0 -0.71 -0.9418 -0.9979 1025381 TimTec1_005946 COc1ccc2CC3N(CCc4cc5OCOc5cc34)Cc2c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O07 compound treatment 44400.0 -7820.0 -0.45 39000.0 -11300.0 -0.86 -0.9271 -0.9556 1512733 TimTec1_005947 COc1ccc(cc1)C2=C(C)C(c3cccs3)c4ccccc4O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O08 compound treatment 40360.0 -11900.0 -0.69 40480.0 -9850.0 -0.75 -1.0134 -0.9992 3088214 TimTec1_005948 COC(=O)c1ccc(cc1)C2OCCCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O09 compound treatment 30400.0 -21800.0 -1.26 28960.0 -21400.0 -1.62 -2.038 -0.9926 3212017 TimTec1_005949 CCN(CC)N=Nc1n[nH]c2nc(C)cc(C)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O10 compound treatment 50080.0 -2140.0 -0.12 39080.0 -11300.0 -0.85 -0.6901 -0.8017 1112286 TimTec1_005950 CC(=O)Nc1ccc(Cl)cc1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O11 compound treatment 37040.0 -15200.0 -0.88 29640.0 -20700.0 -1.57 -1.7296 -0.9628 3212018 TimTec1_005951 C1C(=CC(=NN=C1c2ccccc2)c3ccccc3)c4c[nH]c5ccccc45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O12 compound treatment 44400.0 -7820.0 -0.45 45360.0 -4970.0 -0.38 -0.5867 -0.9957 3212019 TimTec1_005952 COc1cc(OC)c(/C=C/2\C(=O)NC(=O)N(C3CCCCC3)C2=O)c(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O13 compound treatment 50800.0 -1420.0 -0.08 43640.0 -6690.0 -0.51 -0.4165 -0.8116 1583863 TimTec1_005953 CCOC(=O)C1(CCN(Cc2cccc(c2)C(=O)O)CC1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O14 compound treatment 49600.0 -2620.0 -0.15 48280.0 -2050.0 -0.16 -0.2173 -0.9999 3212020 TimTec1_005954 COC(=O)c1c(NC(NC(=O)C)(C(F)(F)F)C(F)(F)F)sc2CN(C)CCc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O15 compound treatment 49560.0 -2660.0 -0.15 44280.0 -6050.0 -0.46 -0.4331 -0.8958 1330742 TimTec1_005955 COc1ccc(cc1)C(=O)c2sc3nc(cc(c4cccs4)c3c2N)c5cccs5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O16 compound treatment 46280.0 -5940.0 -0.34 40520.0 -9810.0 -0.74 -0.7687 -0.9389 1008206 TimTec1_005956 NNc1ccc(Br)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O17 compound treatment 43760.0 -8460.0 -0.49 39680.0 -10700.0 -0.81 -0.9169 -0.9716 3212021 TimTec1_005957 C/N=C\1/S/C(=C\c2sccc2C)/C(=O)N1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O18 compound treatment 55760.0 3540.0 0.2 42800.0 -7530.0 -0.57 -0.2583 -0.4263 1627835 TimTec1_005958 OC(C(=O)NN1CCCCC1)(c2ccsc2)c3ccsc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O19 compound treatment 24840.0 -27400.0 -1.59 17080.0 -33300.0 -2.52 -2.9017 -0.9752 3088220 TimTec1_005959 C/C(=N/O)/C1CCCCCCCCCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O20 compound treatment 46040.0 -6180.0 -0.36 47120.0 -3210.0 -0.24 -0.4253 -0.9822 3212022 TimTec1_005960 Fc1cccc(C(=O)N2CCCCC2)c1F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O21 compound treatment 46880.0 -5340.0 -0.31 39120.0 -11200.0 -0.85 -0.8191 -0.9066 1373583 TimTec1_005961 Clc1ccc(cc1)C2(CC(=O)N3CCCCC3)C(=O)c4ccccc4C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O22 compound treatment 56080.0 3860.0 0.22 50160.0 -173.0 -0.01 0.1488 0.6646 1018702 TimTec1_005962 Oc1ccccc1C(=O)N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O23 mock treatment 53200.0 976.0 0.06 52560.0 2230.0 0.17 0.1592 0.8953 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 O24 mock treatment 64280.0 12100.0 0.7 53320.0 2990.0 0.23 0.6538 0.8905 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P01 compound treatment 21160.0 -31100.0 -1.8 11760.0 -38600.0 -2.92 -3.3372 -0.973 1707498 TimTec1_005963 COc1ccc(C(=O)c2ccccc2)c(OCC(=O)NC3(CC4CC5CC(C4)C3)C5)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P02 compound treatment 44120.0 -8100.0 -0.47 37440.0 -12900.0 -0.98 -1.0221 -0.9438 3088297 TimTec1_005964 CC1(C)COP(=S)(OC1)N(C2=NCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P03 compound treatment 46440.0 -5780.0 -0.34 47520.0 -2810.0 -0.21 -0.3875 -0.976 3212023 TimTec1_005965 CCC1CC(O)C(C)C(C)S1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P04 compound treatment 50320.0 -1900.0 -0.11 41920.0 -8410.0 -0.64 -0.5283 -0.8174 3088299 TimTec1_005966 Oc1c(Cl)cc(Cl)cc1C(O)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P05 compound treatment 31320.0 -20900.0 -1.21 28200.0 -22100.0 -1.68 -2.041 -0.9873 1497087 TimTec1_005967 COc1ccccc1n2c(CSc3ccccn3)nc4ccccc4c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P06 compound treatment 9000.0 -43200.0 -2.5 12720.0 -37600.0 -2.85 -3.784 -0.998 3088301 TimTec1_005968 FC(F)(F)c1ccc(cc1)C(=O)NCCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P07 compound treatment 44800.0 -7420.0 -0.43 38480.0 -11900.0 -0.9 -0.9385 -0.9433 3212024 TimTec1_005969 Brc1cccc(CSCC(=O)Nc2ccc3ccccc3c2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P08 compound treatment 20240.0 -32000.0 -1.85 18800.0 -31500.0 -2.39 -2.9981 -0.9922 3212086 TimTec1_005970 Cc1cc(Cl)ccc1OC2C(N(C2=O)c3cccc(c3)C(F)(F)F)c4ccc5OCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P09 compound treatment 39200.0 -13000.0 -0.75 31800.0 -18500.0 -1.4 -1.5255 -0.9577 1275002 TimTec1_005971 CC(NC(=O)NC1(CC1)c2ccccc2)C3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P10 compound treatment 43200.0 -9020.0 -0.52 40000.0 -10300.0 -0.78 -0.9227 -0.9808 1579554 TimTec1_005972 COc1ccc(cc1OC)C2SCC(=O)N2CCN3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P11 compound treatment 34400.0 -17800.0 -1.03 29080.0 -21300.0 -1.61 -1.8677 -0.977 3088305 TimTec1_005973 CNc1nc(cc(n1)C(F)(F)F)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P12 compound treatment 42960.0 -9260.0 -0.54 39080.0 -11300.0 -0.85 -0.9818 -0.9752 1420064 TimTec1_005974 Fc1ccccc1c2nnn(CC(=O)NCc3ccc4OCOc4c3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P13 compound treatment 34080.0 -18100.0 -1.05 34800.0 -15500.0 -1.18 -1.5747 -0.9984 1669226 TimTec1_005975 CCOC(=O)C1=C(N)CC(NC1c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P14 compound treatment 45360.0 -6860.0 -0.4 43160.0 -7170.0 -0.54 -0.6651 -0.9883 3088307 TimTec1_005976 COc1cc(ccc1n2cnnn2)n3cnnn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P15 compound treatment 37080.0 -15100.0 -0.88 42240.0 -8090.0 -0.61 -1.0536 -0.9846 1638981 TimTec1_005977 COc1ccc(NC(=O)C2(CCCCC2)N(C(=O)Cn3nnnc3N)c4ccc(OC)cc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P16 compound treatment 37240.0 -15000.0 -0.87 31720.0 -18600.0 -1.41 -1.6101 -0.9729 1387660 TimTec1_005978 CN(C)c1ccc(cc1)C(N2C(CC2=O)c3ccco3)C(=O)Nc4c(C)cccc4C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P17 compound treatment 42800.0 -9420.0 -0.55 42400.0 -7930.0 -0.6 -0.8107 -0.9989 1166206 TimTec1_005979 Cc1cc(C)n2nc(nc2n1)S(=O)(=O)N(CC=C)CC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P18 compound treatment 12760.0 -39500.0 -2.29 13200.0 -37100.0 -2.81 -3.6042 -0.9948 3088310 TimTec1_005980 Cc1ccccc1CSc2nnc3c4ccccc4n(CC=C)c3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P19 compound treatment 14080.0 -38100.0 -2.21 12960.0 -37400.0 -2.83 -3.563 -0.9925 3212087 TimTec1_005981 CC(=O)NC(NCC1(CC2CC3CC(C2)C1)C3)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P20 compound treatment 37240.0 -15000.0 -0.87 37440.0 -12900.0 -0.98 -1.3039 -0.9983 3212088 TimTec1_005982 Brc1ccc2nc(oc(=O)c2c1)c3ccc4C(=O)N(C5CCCCC5)C(=O)c4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P21 compound treatment 40440.0 -11800.0 -0.68 37320.0 -13000.0 -0.98 -1.1792 -0.984 1700737 TimTec1_005983 Cc1ccc(cc1S(=O)(=O)NCc2ccccn2)c3nnc(Nc4ccccc4)c5ccccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P22 compound treatment 41600.0 -10600.0 -0.62 35680.0 -14700.0 -1.11 -1.2195 -0.9614 3212089 TimTec1_005984 CN1CCC(CC1)OC(=O)c2cc3cc(Br)ccc3oc2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P23 mock treatment 43880.0 -8340.0 -0.48 47360.0 -2970.0 -0.23 -0.5009 -0.9394 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2079 P24 mock treatment 54640.0 2420.0 0.14 40280.0 -10100.0 -0.76 -0.4391 -0.5675 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A01 compound treatment 56680.0 4890.0 0.28 68640.0 13500.0 1.02 0.9207 0.8706 1333525 TimTec1_005985 COc1ccc(cc1OC)C(=O)N2CCN(CC2)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A02 compound treatment 1040.0 -50800.0 -2.94 1520.0 -53700.0 -4.06 -4.9513 -0.9874 3088315 TimTec1_005986 Cc1n(Cc2ccccc2)c(O)cc3nn(c4nc5ccccc5s4)c(=O)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A03 compound treatment 35440.0 -16400.0 -0.95 54600.0 -579.0 -0.04 -0.7009 -0.739 3088316 TimTec1_005987 CN(C)S(=O)(=O)c1cccc2N=S=Nc21 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A04 compound treatment 25840.0 -26000.0 -1.5 26680.0 -28500.0 -2.16 -2.5886 -0.9844 3088391 TimTec1_005988 COc1ccc(OC2C(N(C2=O)c3cccc(c3)C(F)(F)F)c4ccc(OC)c(OC)c4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A05 compound treatment 31000.0 -20800.0 -1.2 43600.0 -11600.0 -0.88 -1.4716 -0.9878 3212090 TimTec1_005989 O=c1n(c2ccccc2n1S(=O)(=O)c3ccccc3)S(=O)(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A06 compound treatment 37920.0 -13900.0 -0.8 45440.0 -9740.0 -0.74 -1.0896 -0.9991 3088394 TimTec1_005990 CCN(CC)c1nc(N)nc(n1)N(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A07 compound treatment 44800.0 -6990.0 -0.41 55840.0 661.0 0.05 -0.2511 -0.6151 3212091 TimTec1_005991 Oc1ccc(CNCC2NCCc3ccccc23)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A08 compound treatment 37360.0 -14400.0 -0.84 47040.0 -8140.0 -0.62 -1.0269 -0.9887 1871268 TimTec1_005992 COc1cc(cc(OC)c1OC)C2Sc3ccccc3NC4=C2C(=O)OC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A09 compound treatment 35240.0 -16600.0 -0.96 44120.0 -11100.0 -0.84 -1.27 -0.9977 3088397 TimTec1_005993 FC(F)(F)c1ccc(cc1)C(=O)Nc2coc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A10 compound treatment 36120.0 -15700.0 -0.91 45160.0 -10000.0 -0.76 -1.1783 -0.996 3212092 TimTec1_005994 COc1ccccc1NC(=O)COc2nsnc2N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A11 compound treatment 47240.0 -4550.0 -0.26 56720.0 1540.0 0.12 -0.104 -0.3606 1380446 TimTec1_005995 CCc1nc2ccccc2n1C(=O)CCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A12 compound treatment 41600.0 -10200.0 -0.59 44800.0 -10400.0 -0.79 -0.9731 -0.9901 3212093 TimTec1_005996 O=C(CC1N(NC(=O)c2ccncc2)C(=S)N(C1=O)c3ccccc3)NCCc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A13 compound treatment 48280.0 -3510.0 -0.2 52720.0 -2460.0 -0.19 -0.2755 -0.999 3088399 TimTec1_005997 CC1(C)CC(CCO1)n2nc(O)cc2N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A14 compound treatment 39600.0 -12200.0 -0.71 40640.0 -14500.0 -1.1 -1.2777 -0.977 3212094 TimTec1_005998 COc1cccc(Nc2ccc(Nc3cccc(OC)c3)nn2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A15 compound treatment 13280.0 -38500.0 -2.23 15080.0 -40100.0 -3.04 -3.724 -0.9885 3212095 TimTec1_005999 CCOc1ccccc1C2C(=CN(CC3(CC4CC5CC(C4)C3)C5)C=C2C(=O)OC)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A16 compound treatment 28480.0 -23300.0 -1.35 31840.0 -23300.0 -1.77 -2.2043 -0.9912 3088402 TimTec1_006000 Clc1ccc(NCc2cc3ccccc3[nH]c2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A17 compound treatment 24000.0 -27800.0 -1.61 31560.0 -23600.0 -1.79 -2.4028 -0.9986 3088404 TimTec1_006001 Clc1cccc(c1)C2NCc3ccccc3-n4cccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A18 compound treatment 54120.0 2330.0 0.13 55200.0 21.3 0.0 0.0965 0.7155 3212096 TimTec1_006002 COc1ccccc1NC(=O)Cn2nc(n(N)c2=S)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A19 compound treatment 42640.0 -9150.0 -0.53 48200.0 -6980.0 -0.53 -0.7485 -1.0 1610618 TimTec1_006003 CN1C(=O)C(CC(=O)Nc2ccc(F)cc2)N(NC(=O)c3cccc(F)c3)C1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A20 compound treatment 43160.0 -8630.0 -0.5 52360.0 -2820.0 -0.21 -0.5045 -0.9279 3088406 TimTec1_006004 O=C1N(CCc2ccccc2)C(NCCc3ccccc3)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A21 compound treatment 52120.0 328.0 0.02 59720.0 4540.0 0.34 0.2565 0.745 3212097 TimTec1_006005 CC1(C)CC(=O)C=C(C1)NCC2NCCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A22 compound treatment 28560.0 -23200.0 -1.35 30800.0 -24400.0 -1.85 -2.2566 -0.988 1307924 TimTec1_006006 NCCOc1ccccc1Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A23 mock treatment 56840.0 5050.0 0.29 69120.0 13900.0 1.06 0.953 0.8703 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 A24 mock treatment 69080.0 17300.0 1.0 59000.0 3820.0 0.29 0.9128 0.8755 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B01 compound treatment 36800.0 -15000.0 -0.87 42840.0 -12300.0 -0.93 -1.2746 -0.9993 3212098 TimTec1_006007 CC(C)(C)c1ccc(cc1)C2CC(=O)c3cnc(N)nc3C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B02 compound treatment 52800.0 1010.0 0.06 51280.0 -3900.0 -0.3 -0.1674 -0.5565 3088409 TimTec1_006008 CC1(C)CC(=O)C2=C(C1)N(C(=O)CC2c3cccnc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B03 compound treatment 31600.0 -20200.0 -1.17 40120.0 -15100.0 -1.14 -1.6333 -0.9999 3212099 TimTec1_006009 Brc1cccc(c1)C(=O)NCCOC2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B04 compound treatment 46720.0 -5070.0 -0.29 56320.0 1140.0 0.09 -0.1467 -0.479 3212100 TimTec1_006010 CC(=O)NC1=NN(C(=O)C)C2(S1)C(=O)N(Cc3ccccc3)c4ccccc42 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B05 compound treatment 21800.0 -30000.0 -1.74 25880.0 -29300.0 -2.22 -2.7969 -0.9927 3088411 TimTec1_006011 COc1cc(OC)cc(c1)C(=O)NCCOC2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B06 compound treatment 46480.0 -5310.0 -0.31 50920.0 -4260.0 -0.32 -0.4456 -0.9997 3212101 TimTec1_006012 COC(=O)C1C(CC(=CC1=O)Nc2ccc(F)cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B07 compound treatment 41680.0 -10100.0 -0.59 46160.0 -9020.0 -0.68 -0.897 -0.9971 3088413 TimTec1_006013 O=S(=O)(Nc1ccc2c(c1)oc3ccccc32)N4CCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B08 compound treatment 52360.0 568.0 0.03 59320.0 4140.0 0.31 0.2449 0.777 3088482 TimTec1_006014 CCN1C(=O)/C(=C\2/C(=O)N3c4c2cc(OC(=O)c5cccs5)cc4C(=CC3(C)C)C)/SC1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B09 compound treatment 12840.0 -39000.0 -2.26 22600.0 -32600.0 -2.47 -3.3396 -0.999 3088485 TimTec1_006015 Fc1ccc(cc1)N2CCN(CC2)C(=O)CSc3nnc(c4ccco4)n3CC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B10 compound treatment 44920.0 -6870.0 -0.4 50240.0 -4940.0 -0.37 -0.5459 -0.9995 3212102 TimTec1_006016 CC1Cn2c(nnc2S1)c3cccc(O)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B11 compound treatment 15720.0 -36100.0 -2.09 15800.0 -39400.0 -2.98 -3.5855 -0.9849 3212103 TimTec1_006017 CCCC(=O)C1=C(CC(C)(C)CC1=O)NCCc2ccc(OCC)c(OCC)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B12 compound treatment 28160.0 -23600.0 -1.37 31720.0 -23500.0 -1.78 -2.2238 -0.9918 3088487 TimTec1_006018 CCOc1cc2CNC(c3cccn3-c2cc1OCC)c4cccc(F)c4F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B13 compound treatment 46560.0 -5230.0 -0.3 53360.0 -1820.0 -0.14 -0.3117 -0.9362 1497125 TimTec1_006019 COC(=O)Cn1c(=O)oc2ccc(Cl)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B14 compound treatment 40560.0 -11200.0 -0.65 50360.0 -4820.0 -0.36 -0.7181 -0.9625 3212104 TimTec1_006020 CCOc1ccc(CCN2C(=O)C3C4CC(C=C4)C3C2=O)cc1OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B15 compound treatment 51560.0 -233.0 -0.01 56520.0 1340.0 0.1 0.0623 0.608 3212105 TimTec1_006021 Cn1c(=O)cc2-c3ccccc3C(=O)c4c(NS(=O)(=O)c5ccccc5)ccc1c24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B16 compound treatment 29080.0 -22700.0 -1.32 35280.0 -19900.0 -1.51 -1.9955 -0.9977 3088490 TimTec1_006022 COc1cccc(Nc2ncccc2C(=O)Nc3ccc(F)cc3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B17 compound treatment 36800.0 -15000.0 -0.87 48200.0 -6980.0 -0.53 -0.9877 -0.9716 3212162 TimTec1_006023 Nc1nonc1c2nc3ccccc3n2CC(=O)N4CCN(CC4)c5ccc(F)cc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B18 compound treatment 52480.0 688.0 0.04 52880.0 -2300.0 -0.17 -0.0949 -0.5315 3088492 TimTec1_006024 CC1(C)CC(=O)C(=C(C1)NCc2ccco2)C(NC(=O)c3ccncc3)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B19 compound treatment 38640.0 -13200.0 -0.76 51120.0 -4060.0 -0.31 -0.7561 -0.9202 3212163 TimTec1_006025 Cc1ccc(cc1)C(=O)c2oc3ccccc3c2NC(=O)CCCN4C(=O)c5ccccc5C4=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B20 compound treatment 45880.0 -5910.0 -0.34 60680.0 5500.0 0.42 0.0522 0.0969 3088494 TimTec1_006026 Clc1ccc(cc1)c2nnc3SC(=C)Cn23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B21 compound treatment 38920.0 -12900.0 -0.75 46280.0 -8900.0 -0.67 -1.0037 -0.9987 3212164 TimTec1_006027 CCN(Cc1ccccc1)C(=O)CSc2nc(C)c(Cl)c(C)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B22 compound treatment 53920.0 2130.0 0.12 60520.0 5340.0 0.4 0.373 0.8826 3088496 TimTec1_006028 Fc1ccc(cc1)S(=O)(=O)NCCN2CCNC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B23 mock treatment 59720.0 7930.0 0.46 61240.0 6060.0 0.46 0.6492 1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 B24 mock treatment 57400.0 5610.0 0.32 69080.0 13900.0 1.05 0.9738 0.8842 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C01 compound treatment 23560.0 -28200.0 -1.64 34480.0 -20700.0 -1.57 -2.2645 -0.9998 3212165 TimTec1_006029 Cc1ccc(cc1Cl)N2CCN(CC2)C(=O)C(c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C02 compound treatment 49280.0 -2510.0 -0.15 54400.0 -779.0 -0.06 -0.1446 -0.9208 3212166 TimTec1_006030 FC(F)(F)c1ccccc1NC(=O)c2ccc(Cn3cnnn3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C03 compound treatment 51160.0 -633.0 -0.04 53200.0 -1980.0 -0.15 -0.1318 -0.8549 3088498 TimTec1_006031 Nc1ccccc1C(=O)Nc2cc(cc(c2)C(=O)O)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C04 compound treatment 30200.0 -21600.0 -1.25 35240.0 -19900.0 -1.51 -1.9518 -0.9957 3212167 TimTec1_006032 CS(=O)(=O)c1nc2ccccc2n1Cc3ccccc3F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C05 compound treatment 19000.0 -32800.0 -1.9 18640.0 -36500.0 -2.77 -3.2991 -0.9832 3088500 TimTec1_006033 Fc1ccccc1C2CC(=O)Nc3cc4CCCc4cc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C06 compound treatment 24000.0 -27800.0 -1.61 30000.0 -25200.0 -1.91 -2.4863 -0.9965 3212168 TimTec1_006034 Oc1ccccc1n2cccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C07 compound treatment 39840.0 -12000.0 -0.69 46960.0 -8220.0 -0.62 -0.9296 -0.9986 3212169 TimTec1_006035 Fc1cccc(F)c1CNCC2NCCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C08 compound treatment 7960.0 -43800.0 -2.54 13480.0 -41700.0 -3.16 -4.0276 -0.9942 3088503 TimTec1_006036 CSC1=NC2(C)CCCCC2c3c1ccc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C09 compound treatment 49960.0 -1830.0 -0.11 55200.0 21.3 0.0 -0.0739 -0.6963 3212170 TimTec1_006037 CC(=O)ON1C(C)(C)Cc2noc(N)c2C1(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C10 compound treatment 25240.0 -26600.0 -1.54 38920.0 -16300.0 -1.23 -1.958 -0.9939 3212171 TimTec1_006038 C(CSc1nnc2c3ccccc3nc(c4ccccc4)n12)Oc5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C11 compound treatment 2760.0 -49000.0 -2.84 5000.0 -50200.0 -3.8 -4.6945 -0.9898 1197164 TimTec1_006039 CC(C)Cc1ccc(cc1)C(C)c2nc3ccccc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C12 compound treatment 50120.0 -1670.0 -0.1 55160.0 -18.8 0.0 -0.0695 -0.7174 3088505 TimTec1_006040 CCOc1cc(CN)c(cc1OCC)n2cccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C13 compound treatment 37560.0 -14200.0 -0.82 41720.0 -13500.0 -1.02 -1.3034 -0.9945 3088575 TimTec1_006041 Clc1ccc(c2ccccc12)S(=O)(=O)NCC3(CC4CC5CC(C4)C3)C5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C14 compound treatment 44520.0 -7270.0 -0.42 50040.0 -5140.0 -0.39 -0.573 -0.9992 1249304 TimTec1_006042 Clc1ccc(NC(=O)NCCc2ccncc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C15 compound treatment 6040.0 -45800.0 -2.65 6400.0 -48800.0 -3.69 -4.4852 -0.9868 3088578 TimTec1_006043 CCc1nc2c3no[n+]([O-])c3c4no[n+]([O-])c4c2[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C16 compound treatment 50440.0 -1350.0 -0.08 52360.0 -2820.0 -0.21 -0.2063 -0.9075 3212172 TimTec1_006044 CCCNC(=O)Cc1nnc[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C17 compound treatment 37240.0 -14600.0 -0.84 49560.0 -5620.0 -0.43 -0.8969 -0.9498 3088580 TimTec1_006045 Cc1ccc(cc1)C(=O)c2nsc(Cl)c2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C18 compound treatment 43400.0 -8390.0 -0.49 55120.0 -58.8 0.0 -0.347 -0.7135 3212173 TimTec1_006046 Cn1ccnc1SCc2cc(=O)[nH]c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C19 compound treatment 46280.0 -5510.0 -0.32 59920.0 4740.0 0.36 0.0279 0.0581 3088582 TimTec1_006047 COC(=O)CC1CC(C)(C)NC(C)(C)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C20 compound treatment 52000.0 208.0 0.01 66800.0 11600.0 0.88 0.6305 0.7167 1686023 TimTec1_006048 CCOC(=O)C1=C(SCC)c2ccc(c3ccccc3)n2C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C21 compound treatment 56600.0 4810.0 0.28 56680.0 1500.0 0.11 0.2773 0.9218 3212174 TimTec1_006049 O=C1CC(CC(=O)C1=CNCC2NCCc3ccccc23)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C22 compound treatment 47600.0 -4190.0 -0.24 55840.0 661.0 0.05 -0.1364 -0.5498 1535965 TimTec1_006050 Brc1ccc(cc1)S(=O)(=O)N2CCNCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C23 mock treatment 52680.0 888.0 0.05 56600.0 1420.0 0.11 0.1124 0.9429 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 C24 mock treatment 56320.0 4530.0 0.26 62120.0 6940.0 0.53 0.557 0.9485 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D01 compound treatment 16680.0 -35100.0 -2.03 19040.0 -36100.0 -2.74 -3.3728 -0.9894 3088585 TimTec1_006051 C/C(=N\S(=O)(=O)c1ccc(C)cc1)/Nc2ccc(O)c(C)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D02 compound treatment 45880.0 -5910.0 -0.34 50440.0 -4740.0 -0.36 -0.4959 -0.9997 3212175 TimTec1_006052 Cn1c(SCSc2nc3n(C)c(=O)n(C)c(=O)c3n2C)nc4n(C)c(=O)n(C)c(=O)c14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D03 compound treatment 37480.0 -14300.0 -0.83 45040.0 -10100.0 -0.77 -1.129 -0.9993 3088587 TimTec1_006053 Cc1ccc(OCc2ccccc2C(=O)Nc3nccs3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D04 compound treatment 25800.0 -26000.0 -1.51 26320.0 -28900.0 -2.18 -2.6095 -0.9835 3212176 TimTec1_006054 O=C1N2C(N(Cc3ccccc3)S(=O)(=O)c4ccccc24)c5ccccc15 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D05 compound treatment 46320.0 -5470.0 -0.32 47640.0 -7540.0 -0.57 -0.6277 -0.9615 3088589 TimTec1_006055 Brc1cncc(c1)C(=O)NCCOc2ccc3ccccc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D06 compound treatment 39040.0 -12800.0 -0.74 43640.0 -11500.0 -0.87 -1.14 -0.9965 3212177 TimTec1_006056 COC(=O)C1C(CC(=CC1=O)Nc2cc(OC)ccc2OC)c3ccc(OC)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D07 compound treatment 42000.0 -9790.0 -0.57 47080.0 -8100.0 -0.61 -0.8347 -0.9993 3212178 TimTec1_006057 CS(=O)(=O)N1CCc2cc(ccc12)S(=O)(=O)Nc3ccc4C(=O)OCc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D08 compound treatment 43160.0 -8630.0 -0.5 52320.0 -2860.0 -0.22 -0.5067 -0.9298 3088591 TimTec1_006058 Cc1ccccc1NC(=O)C2C3N4C(=O)CSC4=NC2(C)Oc5ccccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D09 compound treatment 34600.0 -17200.0 -1.0 35760.0 -19400.0 -1.47 -1.7437 -0.982 3212179 TimTec1_006059 CC(=C1C(=O)CC(CC1=O)c2ccccc2)NCCc3c(C)[nH]c4ccc(OC(F)(F)F)cc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D10 compound treatment 36920.0 -14900.0 -0.86 45320.0 -9860.0 -0.75 -1.137 -0.9974 3212180 TimTec1_006060 OCCCn1c(cn2c(c(nc12)c3ccccc3)c4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D11 compound treatment 36400.0 -15400.0 -0.89 42000.0 -13200.0 -1.0 -1.336 -0.9984 1303635 TimTec1_006061 S=C(NCc1ccccc1)N2CCN(Cc3ccc4OCOc4c3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D12 compound treatment 21720.0 -30100.0 -1.74 27960.0 -27200.0 -2.06 -2.6889 -0.9965 3212181 TimTec1_006062 CCOc1cc2CNC(C3CCCCC3)c4cccn4-c2cc1OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D13 compound treatment 35720.0 -16100.0 -0.93 43960.0 -11200.0 -0.85 -1.2589 -0.9989 3088595 TimTec1_006063 COc1ccc(cc1)C(=O)N(CC(=O)Nc2nn(nc2C(=O)N)c3ccccc3)Cc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D14 compound treatment 47720.0 -4070.0 -0.24 46800.0 -8380.0 -0.63 -0.6153 -0.9093 3212182 TimTec1_006064 CC(C1CC(=O)N(C1=O)c2ccc(OC(F)(F)F)cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D15 compound treatment 46800.0 -4990.0 -0.29 52240.0 -2940.0 -0.22 -0.3618 -0.9916 3212183 TimTec1_006065 COc1nc(NCCC2=CCCCC2)nc(n1)N3CC4CC(C3)c5cccc(=O)n5C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D16 compound treatment 36520.0 -15300.0 -0.88 40600.0 -14600.0 -1.1 -1.406 -0.994 3087442 TimTec1_006066 Oc1cccc(/C=N/N2CCCCC2)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D17 compound treatment 34040.0 -17800.0 -1.03 42800.0 -12400.0 -0.94 -1.3898 -0.9989 3212184 TimTec1_006067 CC1=C(C(c2ccc(C)o2)n3c(N1)nc4ccccc34)C(=O)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D18 compound treatment 8160.0 -43600.0 -2.53 13880.0 -41300.0 -3.13 -3.998 -0.9945 1863683 TimTec1_006068 COc1cccc(CNC2(CC3CC4CC(C3)C2)C4)c1OCc5ccccc5F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D19 compound treatment 50640.0 -1150.0 -0.07 55360.0 181.0 0.01 -0.0375 -0.5503 3212185 TimTec1_006069 COc1ccc(cc1)C2C3C(SC(=C2C#N)N)C(=O)N(C3=O)c4ccc(Br)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D20 compound treatment 43200.0 -8590.0 -0.5 53880.0 -1300.0 -0.1 -0.4215 -0.8307 3087446 TimTec1_006070 Clc1ccc(CN2COc3ccc(Cl)cc3C2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D21 compound treatment 47560.0 -4230.0 -0.25 48880.0 -6300.0 -0.48 -0.5105 -0.9522 3212186 TimTec1_006071 CN(C(=O)CSc1nc(C)c(C)c(C)c1C#N)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D22 compound treatment 46760.0 -5030.0 -0.29 55160.0 -18.8 0.0 -0.2072 -0.7105 1200722 TimTec1_006072 O=C1NCCN1CCNS(=O)(=O)c2ccc3ccccc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D23 mock treatment 51960.0 168.0 0.01 66480.0 11300.0 0.86 0.6118 0.7151 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 D24 mock treatment 58880.0 7090.0 0.41 58400.0 3220.0 0.24 0.4628 0.969 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E01 compound treatment 37560.0 -14200.0 -0.82 40280.0 -14900.0 -1.13 -1.3805 -0.9882 1327534 TimTec1_006073 CCNc1nc(NCC)n2c(SCC(=O)N(c3ccccc3)c4ccccc4)nnc2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E02 compound treatment 49360.0 -2430.0 -0.14 50560.0 -4620.0 -0.35 -0.3469 -0.9202 3212187 TimTec1_006074 O=C(NCCc1ccncc1)NC2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E03 compound treatment 47280.0 -4510.0 -0.26 56960.0 1780.0 0.13 -0.0895 -0.3044 3087449 TimTec1_006075 CCCn1ncc(C(=O)O)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E04 compound treatment 41960.0 -9830.0 -0.57 47400.0 -7780.0 -0.59 -0.8192 -0.9999 3212246 TimTec1_006076 O=C(CSc1nnc2sc3ccccc3n12)N4CCc5ccccc5C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E05 compound treatment 14840.0 -37000.0 -2.14 22560.0 -32600.0 -2.47 -3.2598 -0.9975 3087451 TimTec1_006077 Cc1ccc(cc1)N2COc3ccc(Cl)cc3C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E06 compound treatment 9520.0 -42300.0 -2.45 18080.0 -37100.0 -2.81 -3.7175 -0.9977 3212247 TimTec1_006078 NC1=C(C#N)C(C2=C(O1)c3ccccc3CC2)c4ccccc4Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E07 compound treatment 39480.0 -12300.0 -0.71 46480.0 -8700.0 -0.66 -0.97 -0.9992 3087453 TimTec1_006079 FC(F)(F)c1ccccc1CNCC2NCCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E08 compound treatment 36560.0 -15200.0 -0.88 44040.0 -11100.0 -0.84 -1.2202 -0.9997 3212248 TimTec1_006080 Cc1ccc(OCCNC(=O)c2ccccc2N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E09 compound treatment 42360.0 -9430.0 -0.55 48800.0 -6380.0 -0.48 -0.7278 -0.9981 3087455 TimTec1_006081 Cc1ccc(cc1)c2ccc(CCC(=O)O)n2c3ccccc3C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E10 compound treatment 42440.0 -9350.0 -0.54 52240.0 -2940.0 -0.22 -0.5404 -0.9227 3212249 TimTec1_006082 CC(=O)N1CCc2ccccc2C1CNC3=CC(=O)CC(C)(C)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E11 compound treatment 40120.0 -11700.0 -0.68 51720.0 -3460.0 -0.26 -0.6633 -0.9147 3087457 TimTec1_006083 COC(=O)c1sc(OC)c(c1O)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E12 compound treatment 38720.0 -13100.0 -0.76 50000.0 -5180.0 -0.39 -0.8127 -0.953 3212250 TimTec1_006084 Cc1[nH]c2ccccc2c1CCNC3=CC(=O)CC(C)(C)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E13 compound treatment 43360.0 -8430.0 -0.49 48960.0 -6220.0 -0.47 -0.6783 -0.9998 3087459 TimTec1_006085 Cc1cc(C)c2c(O)nn(C3CCCC3)c2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E14 compound treatment 44320.0 -7470.0 -0.43 54320.0 -859.0 -0.07 -0.3521 -0.8043 3212251 TimTec1_006086 NC(=O)CCN1CCn2c1nc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E15 compound treatment 43160.0 -8630.0 -0.5 52040.0 -3140.0 -0.24 -0.5217 -0.9421 3212252 TimTec1_006087 Cc1ccc(C)c(c1)N/2C(=O)CS\C2=C(\C#N)/S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E16 compound treatment 17720.0 -34100.0 -1.97 24200.0 -31000.0 -2.34 -3.054 -0.9963 1724768 TimTec1_006088 CCCn1c(nc2ccccc12)c3ccc(OC)c(OC)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E17 compound treatment 43440.0 -8350.0 -0.48 47440.0 -7740.0 -0.59 -0.7564 -0.9955 1293720 TimTec1_006089 CCc1ccccc1NC(=O)CSc2nc3n(C)c(=O)n(C)c(=O)c3n2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E18 compound treatment 47200.0 -4590.0 -0.27 52160.0 -3020.0 -0.23 -0.3497 -0.9971 3212253 TimTec1_006090 CC(C)CC1(NC(C2C1C(=O)N(C(C)C)C2=O)c3ccccc3O)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E19 compound treatment 49720.0 -2070.0 -0.12 49080.0 -6100.0 -0.46 -0.4113 -0.8623 3087463 TimTec1_006091 Clc1cccc(c1)C(=O)N2CCNC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E20 compound treatment 28880.0 -22900.0 -1.33 37360.0 -17800.0 -1.35 -1.8924 -1.0 3087465 TimTec1_006092 O=C1C(=C(N2CCCCC2)c3cc4CCCCc4n13)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E21 compound treatment 50320.0 -1470.0 -0.09 55080.0 -98.8 -0.01 -0.0656 -0.7661 3087466 TimTec1_006093 COC(=O)c1cc(=O)nc2sc3ccccc3n12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E22 compound treatment 49960.0 -1830.0 -0.11 58920.0 3740.0 0.28 0.1252 0.4139 1602387 TimTec1_006094 OC(=O)c1cccc(c1)S(=O)(=O)N2CCc3ccccc3C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E23 mock treatment 53080.0 1290.0 0.07 59080.0 3900.0 0.3 0.2616 0.8588 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 E24 mock treatment 50240.0 -1550.0 -0.09 55960.0 781.0 0.06 -0.0218 -0.2024 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F01 compound treatment 47720.0 -4070.0 -0.24 44520.0 -10700.0 -0.81 -0.7373 -0.8772 1511411 TimTec1_006095 Cc1ccc2oc(=O)c(CCC(=O)O)nc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F02 compound treatment 39520.0 -12300.0 -0.71 48520.0 -6660.0 -0.5 -0.8592 -0.9858 3087806 TimTec1_006096 CC(=O)Nc1nonc1c2nc3ccccc3n2Cc4ccccn4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F03 compound treatment 47280.0 -4510.0 -0.26 49840.0 -5340.0 -0.4 -0.4706 -0.9778 3212254 TimTec1_006097 OCCNC(=O)c1cccc(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F04 compound treatment 19840.0 -32000.0 -1.85 25960.0 -29200.0 -2.21 -2.8729 -0.9961 3212255 TimTec1_006098 Fc1ccccc1Cn2cnc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F05 compound treatment 37640.0 -14200.0 -0.82 46560.0 -8620.0 -0.65 -1.0411 -0.9936 3087807 TimTec1_006099 COc1ccccc1NC(=O)c2ccccc2NS(=O)(=O)N3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F06 compound treatment 34160.0 -17600.0 -1.02 41840.0 -13300.0 -1.01 -1.4363 -1.0 3212256 TimTec1_006100 CCOC(=O)C1C(CC(=CC1=O)Nc2ccc(cc2)C(F)(F)F)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F07 compound treatment 30480.0 -21300.0 -1.23 32720.0 -22500.0 -1.7 -2.0752 -0.9877 3212257 TimTec1_006101 O=C(N1CCc2ccccc2C1)c3ccccc3C(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F08 compound treatment 12880.0 -38900.0 -2.25 14760.0 -40400.0 -3.06 -3.7575 -0.9887 3212258 TimTec1_006102 CC12CCC3C(CCC4CCCCC43C)C2C/C(=C\c5ccc[nH]5)/C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F09 compound treatment 38080.0 -13700.0 -0.79 44480.0 -10700.0 -0.81 -1.1344 -1.0 3087808 TimTec1_006103 CCc1c2C(=O)CCCc2nn1c3cc(Cl)ccc3OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F10 compound treatment 8200.0 -43600.0 -2.53 11560.0 -43600.0 -3.3 -4.1206 -0.9912 3087809 TimTec1_006104 C/C=C/C1OC23CCCCC3C(C#N)(C(=N)O2)C1(C#N)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F11 compound treatment 45200.0 -6590.0 -0.38 53760.0 -1420.0 -0.11 -0.346 -0.8721 3212259 TimTec1_006105 FC(F)(F)c1nnc2ccc(nn12)n3ccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F12 compound treatment 43440.0 -8350.0 -0.48 58400.0 3220.0 0.24 -0.1698 -0.3133 3087810 TimTec1_006106 COC(=O)CC1=NN(C(=O)C1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F13 compound treatment 32760.0 -19000.0 -1.1 42600.0 -12600.0 -0.95 -1.453 -0.9973 3212260 TimTec1_006107 COC(=O)C1C(=CN(CCc2ccccc2)C=C1C(=O)OC)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F14 compound treatment 29800.0 -22000.0 -1.27 36200.0 -19000.0 -1.44 -1.9168 -0.9982 3212261 TimTec1_006108 Clc1cccc(NC(=S)NC2(CC3CC4CC(C3)C2)C4)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F15 compound treatment 40920.0 -10900.0 -0.63 51960.0 -3220.0 -0.24 -0.6177 -0.9146 3212262 TimTec1_006109 COc1ccc(CCNc2nc(Cl)nc(n2)N3CC4CC(C3)c5cccc(=O)n5C4)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F16 compound treatment 43080.0 -8710.0 -0.5 44040.0 -11100.0 -0.84 -0.9531 -0.9699 3087811 TimTec1_006110 CC1CCCCN1C(=S)NCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F17 compound treatment 23560.0 -28200.0 -1.64 26760.0 -28400.0 -2.15 -2.6777 -0.9909 3087812 TimTec1_006111 CC(=O)Oc1cc(OC(=O)C)c(cc1Cl)C2(C)CC(C)(C)c3cc(Cl)c(OC(=O)C)cc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F18 compound treatment 28680.0 -23100.0 -1.34 36640.0 -18500.0 -1.4 -1.9391 -0.9997 3212263 TimTec1_006112 COc1cccc(c1)C2C(=C(C)Nc3nc4ccccc4n23)C(=O)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F19 compound treatment 36520.0 -15300.0 -0.88 42560.0 -12600.0 -0.96 -1.3011 -0.9993 3212264 TimTec1_006113 FC(F)(F)COC(=O)C1CCCCC1C(=O)NCC2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F20 compound treatment 46400.0 -5390.0 -0.31 38960.0 -16200.0 -1.23 -1.089 -0.8597 3087813 TimTec1_006114 Clc1ccc(CCN2COc3ccc(Cl)cc3C2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F21 compound treatment 37560.0 -14200.0 -0.82 41920.0 -13300.0 -1.0 -1.2927 -0.9952 3087814 TimTec1_006115 CCCN(CCC)S(=O)(=O)c1ccc(OC)c2ncccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F22 compound treatment 49600.0 -2190.0 -0.13 57720.0 2540.0 0.19 0.0462 0.2004 3212265 TimTec1_006116 CCOC(=O)c1nnn(c1C)c2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F23 mock treatment 54720.0 2930.0 0.17 58720.0 3540.0 0.27 0.3095 0.9756 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 F24 mock treatment 52200.0 408.0 0.02 55280.0 101.0 0.01 0.0221 0.8909 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G01 compound treatment 46920.0 -4870.0 -0.28 49760.0 -5420.0 -0.41 -0.4897 -0.9834 1567525 TimTec1_006117 Ic1ccc(cc1)N(Cc2nnc3CCCCCn23)C(=O)Nc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G02 compound treatment 36560.0 -15200.0 -0.88 42040.0 -13100.0 -0.99 -1.3273 -0.9982 3087815 TimTec1_006118 Fc1ccccc1C(=O)N2C=Cc3ccccc3C2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G03 compound treatment 39640.0 -12200.0 -0.7 45400.0 -9780.0 -0.74 -1.0213 -0.9997 3212266 TimTec1_006119 Cc1[nH]c2ccccc2c1CCNC(=O)NC(=O)c3ccc(cc3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G04 compound treatment 44040.0 -7750.0 -0.45 54520.0 -659.0 -0.05 -0.3529 -0.7808 3087816 TimTec1_006120 CCOC(=O)c1oc2ccc(Cl)cc2c1NC(=O)CCCN3C(=O)c4ccccc4C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G05 compound treatment 20560.0 -31200.0 -1.81 31440.0 -23700.0 -1.8 -2.5501 -1.0 3212267 TimTec1_006121 COCc1cc(C)nc2sc(C(=O)OC)c(n3cccc3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G06 compound treatment 18280.0 -33500.0 -1.94 25960.0 -29200.0 -2.21 -2.9368 -0.9979 3212268 TimTec1_006122 Cc1cnc-2c(c1)/C(=N\c3ccccc3)/c4ccccc42 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G07 compound treatment 29920.0 -21900.0 -1.27 42000.0 -13200.0 -1.0 -1.6015 -0.993 3087817 TimTec1_006123 CN(C)S(=O)(=O)c1cc(C(=O)NCCc2c(C)n(C)c3ccccc23)c(Cl)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G08 compound treatment 37160.0 -14600.0 -0.85 42200.0 -13000.0 -0.98 -1.2941 -0.9973 3212269 TimTec1_006124 CC(=O)N1C(CC(=O)C(C1c2ccccc2)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G09 compound treatment 22840.0 -29000.0 -1.68 34440.0 -20700.0 -1.57 -2.2962 -0.9995 3212270 TimTec1_006125 C(c1ccccc1)n2ncc3c4nc(nn4cnc23)c5ccncc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G10 compound treatment 43600.0 -8190.0 -0.47 47400.0 -7780.0 -0.59 -0.752 -0.9943 3087818 TimTec1_006126 COc1ccc(cc1)C(=O)c2coc3ccc(O)c(CN4CCCC4)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G11 compound treatment 37200.0 -14600.0 -0.85 48000.0 -7180.0 -0.54 -0.9821 -0.9772 3212271 TimTec1_006127 CC1(C)Cc2ccccc2C(=N1)c3sc4nc(cc(c4c3N)C(F)(F)F)c5cccs5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G12 compound treatment 38160.0 -13600.0 -0.79 45120.0 -10100.0 -0.76 -1.0969 -0.9998 3087819 TimTec1_006128 CCOC(=O)C1(C2C1(C)C(=O)c3ccc(Br)cc3)C(=O)OC2(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G13 compound treatment 39280.0 -12500.0 -0.72 42960.0 -12200.0 -0.92 -1.1666 -0.9927 3212272 TimTec1_006129 CC(C)n1nc(O)c2c(C)cc(C)nc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G14 compound treatment 15520.0 -36300.0 -2.1 22600.0 -32600.0 -2.47 -3.2298 -0.9968 3087821 TimTec1_006130 C1COc2cc(/N=C/3\CCCCCN3)ccc2O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G15 compound treatment 20040.0 -31800.0 -1.84 29120.0 -26100.0 -1.97 -2.6956 -0.9994 3212330 TimTec1_006131 CCN1C(=C(C(=O)OC)/C(=C/c2ccc(OC)cc2)/C1=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G16 compound treatment 43880.0 -7910.0 -0.46 48040.0 -7140.0 -0.54 -0.7063 -0.9967 3212331 TimTec1_006132 CCOc1nc(NC(=O)NS(=O)(=O)c2cccc(Cl)c2)nc(n1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G17 compound treatment 38680.0 -13100.0 -0.76 40600.0 -14600.0 -1.1 -1.3175 -0.9834 1578073 TimTec1_006133 Cn1c(SCc2ccc(F)cc2)nc3n(C)c(=O)n(C)c(=O)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G18 compound treatment 43640.0 -8150.0 -0.47 50000.0 -5180.0 -0.39 -0.6112 -0.9957 3212332 TimTec1_006134 FC(F)(F)COC(=O)C1CCCCC1C(=O)NCCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G19 compound treatment 42240.0 -9550.0 -0.55 54000.0 -1180.0 -0.09 -0.4544 -0.8106 3087826 TimTec1_006135 COc1cccc(c1)C(=O)NN2C(CC(=O)N)C(=O)N(C2=S)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G20 compound treatment 47040.0 -4750.0 -0.28 49800.0 -5380.0 -0.41 -0.4826 -0.9819 3212333 TimTec1_006136 COC(=O)C1CCCNC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G21 compound treatment 15600.0 -36200.0 -2.1 17640.0 -37500.0 -2.84 -3.492 -0.9888 3212334 TimTec1_006137 CCc1ccc(cc1)C2NCc3ccccc3-n4cccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G22 compound treatment 49360.0 -2430.0 -0.14 53600.0 -1580.0 -0.12 -0.1842 -0.9966 3087829 TimTec1_006138 CCOC(=O)C1CC(=NO1)CC2OCCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G23 mock treatment 48360.0 -3430.0 -0.2 58720.0 3540.0 0.27 0.0489 0.1466 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 G24 mock treatment 54440.0 2650.0 0.15 54600.0 -579.0 -0.04 0.0775 0.4857 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H01 compound treatment 27960.0 -23800.0 -1.38 31120.0 -24100.0 -1.82 -2.2641 -0.9907 3212335 TimTec1_006139 CCC(=O)C1=C(CCCC1=O)NCCc2c(C)[nH]c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H02 compound treatment 44840.0 -6950.0 -0.4 50000.0 -5180.0 -0.39 -0.562 -0.9999 3087831 TimTec1_006140 CCn1cc(C(=O)O)c(=O)c2cnc(nc12)N3CCN(CC3)C(=S)NC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H03 compound treatment 39120.0 -12700.0 -0.73 48200.0 -6980.0 -0.53 -0.8927 -0.987 3212336 TimTec1_006141 Clc1ccc(cc1Cl)S(=O)(=O)N2CCCC2C(=O)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H04 compound treatment 32360.0 -19400.0 -1.13 37720.0 -17500.0 -1.32 -1.7306 -0.9968 3087877 TimTec1_006142 CN(c1ccccc1)c2nc(nc(n2)n3ccnc3)n4ccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H05 compound treatment 33040.0 -18800.0 -1.09 41720.0 -13500.0 -1.02 -1.4886 -0.9995 3087880 TimTec1_006143 COC(=O)/C=C/CSc1nnc(o1)c2ccc(Cl)cc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H06 compound treatment 33800.0 -18000.0 -1.04 34200.0 -21000.0 -1.59 -1.86 -0.9792 3212337 TimTec1_006144 CCOC(=O)C1C(CC(=CC1=O)Nc2sc3CCCCc3c2C#N)c4cccc(OC)c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H07 compound treatment 27800.0 -24000.0 -1.39 36200.0 -19000.0 -1.44 -1.9987 -0.9999 3087882 TimTec1_006145 CCc1ccc(OCC(=O)Nc2ccc3C(=O)OCc3c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H08 compound treatment 34360.0 -17400.0 -1.01 43160.0 -12000.0 -0.91 -1.3575 -0.9986 3212338 TimTec1_006146 Cc1nc2ccccc2nc1CSc3nnc(Cc4ccccc4)n3c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H09 compound treatment 24960.0 -26800.0 -1.55 36960.0 -18200.0 -1.38 -2.0744 -0.9982 3087884 TimTec1_006147 CCCCc1c2C(=O)CC(Cc2nn1c3ccccc3F)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H10 compound treatment 42480.0 -9310.0 -0.54 57000.0 1820.0 0.14 -0.284 -0.51 3212339 TimTec1_006148 COC1OC2COC(C2O)C1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H11 compound treatment 46320.0 -5470.0 -0.32 53560.0 -1620.0 -0.12 -0.3108 -0.9145 1214251 TimTec1_006149 CC(O)Cn1c(O)cc(C)c(C#N)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H12 compound treatment 25480.0 -26300.0 -1.52 31320.0 -23900.0 -1.81 -2.355 -0.9964 3212340 TimTec1_006150 Oc1ccccc1N2CCN(CC2)C(=S)NCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H13 compound treatment 39640.0 -12200.0 -0.7 45600.0 -9580.0 -0.73 -1.0106 -0.9999 3212341 TimTec1_006151 CCN(CC)C(=O)NC(=O)c1c(C)cc(Cl)nc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H14 compound treatment 29640.0 -22200.0 -1.28 36600.0 -18600.0 -1.41 -1.902 -0.999 1411377 TimTec1_006152 CN(C1CCCCC1)C(=S)NCCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H15 compound treatment 16440.0 -35400.0 -2.05 13440.0 -41700.0 -3.16 -3.6824 -0.978 3212342 TimTec1_006153 COC(=O)C1=CN(CCOC2(CC3CC4CC(C3)C2)C4)C=C(C1c5cccc(F)c5)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H16 compound treatment 35800.0 -16000.0 -0.93 45240.0 -9940.0 -0.75 -1.1871 -0.9947 1662088 TimTec1_006154 CC1CCCCN1C(=S)NCCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H17 compound treatment 41320.0 -10500.0 -0.61 51440.0 -3740.0 -0.28 -0.6292 -0.9397 3212343 TimTec1_006155 Sc1nc(c(c2ccccc2)n1CC(=O)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H18 compound treatment 39280.0 -12500.0 -0.72 49760.0 -5420.0 -0.41 -0.8026 -0.9636 3087889 TimTec1_006156 Cc1cc2nc([nH]c2cc1C)S(=O)(=O)Cc3cccc(c3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H19 compound treatment 36920.0 -14900.0 -0.86 44280.0 -10900.0 -0.82 -1.1926 -0.9998 3212344 TimTec1_006157 CCc1nc(N2CCCCC2)c3sc(=S)n(c4ccccc4)c3n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H20 compound treatment 41840.0 -9950.0 -0.58 53040.0 -2140.0 -0.16 -0.5222 -0.8719 3212345 TimTec1_006158 N#Cc1nc(nc(n1)N2CCCC2)N(c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H21 compound treatment 40320.0 -11500.0 -0.66 47200.0 -7980.0 -0.6 -0.8971 -0.9989 3087892 TimTec1_006159 CN(C)c1nc(Oc2ccc(O)nn2)nc(n1)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H22 compound treatment 42760.0 -9030.0 -0.52 48160.0 -7020.0 -0.53 -0.7457 -1.0 3212346 TimTec1_006160 CCOc1ccc(CC(=C2C(=O)CC(C)(C)CC2=O)Nc3ccccc3O)cc1OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H23 mock treatment 53200.0 1410.0 0.08 59240.0 4060.0 0.31 0.275 0.8648 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 H24 mock treatment 48600.0 -3190.0 -0.18 56040.0 861.0 0.07 -0.0847 -0.4318 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I01 compound treatment 42320.0 -9470.0 -0.55 48320.0 -6860.0 -0.52 -0.7552 -0.9996 1646660 TimTec1_006161 CC1(C)CC(CC(C)(C)N1)NC(=O)NC2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I02 compound treatment 27280.0 -24500.0 -1.42 38240.0 -16900.0 -1.28 -1.9109 -0.9987 3212347 TimTec1_006162 CCOC(=O)C1CCCc2c1[nH]c3ccc(cc23)C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I03 compound treatment 27960.0 -23800.0 -1.38 33240.0 -21900.0 -1.66 -2.1506 -0.9958 3212348 TimTec1_006163 CCCS(=O)(=O)c1c(C(=O)c2ccc(F)cc2)n3ccc(CC)cc3c1S(=O)(=O)CCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I04 compound treatment 11920.0 -39900.0 -2.31 16000.0 -39200.0 -2.97 -3.7305 -0.9924 1516298 TimTec1_006164 CCOC(=O)c1c(CC(C#N)(c2ccccc2)c3ccccc3)oc4ccc(OC)cc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I05 compound treatment 17120.0 -34700.0 -2.01 27880.0 -27300.0 -2.07 -2.8816 -0.9999 3212349 TimTec1_006165 Cc1cc(C)c2c(c(sc2n1)C(=O)Oc3ccccc3)n4cccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I06 compound treatment 37880.0 -13900.0 -0.81 53480.0 -1700.0 -0.13 -0.6609 -0.8097 3087896 TimTec1_006166 Cc1ccc(cc1)c2ccc(N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I07 compound treatment 44320.0 -7470.0 -0.43 49320.0 -5860.0 -0.44 -0.6197 -0.9999 3087898 TimTec1_006167 CN(C1CCN(C)CC1)C(=O)c2ccccc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I08 compound treatment 41400.0 -10400.0 -0.6 44680.0 -10500.0 -0.79 -0.9877 -0.9906 1801410 TimTec1_006168 CCC(Sc1ncccn1)C(=O)Nc2cc(C)on2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I09 compound treatment 38360.0 -13400.0 -0.78 45920.0 -9260.0 -0.7 -1.0459 -0.9986 3087935 TimTec1_006169 FC(F)(F)c1nc2sc3ccccc3n2c(=N)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I10 compound treatment 680.0 -51100.0 -2.96 520.0 -54700.0 -4.14 -5.0195 -0.9866 3087938 TimTec1_006170 Cc1nc(Cl)c2sc(=S)n(c3ccccc3)c2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I11 compound treatment 41800.0 -9990.0 -0.58 49040.0 -6140.0 -0.46 -0.7379 -0.9941 3212350 TimTec1_006171 Cc1cc(NC(=O)C2CC(=O)OC2c3ccccc3)no1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I12 compound treatment 36320.0 -15500.0 -0.9 43880.0 -11300.0 -0.86 -1.2386 -0.9997 3212351 TimTec1_006172 CC1(C)CC(=O)c2cnc(NC3OC(=O)c4ccccc34)nc2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I13 compound treatment 30800.0 -21000.0 -1.22 39400.0 -15800.0 -1.19 -1.7046 -1.0 1875964 TimTec1_006173 CSc1nc2n(ncc2c(=O)n1N)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I14 compound treatment 41000.0 -10800.0 -0.63 46840.0 -8340.0 -0.63 -0.8885 -1.0 3212352 TimTec1_006174 Fc1ccccc1N2CCN(CC2)C(=O)c3cc4cccc(CC=C)c4oc3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I15 compound treatment 42280.0 -9510.0 -0.55 47960.0 -7220.0 -0.55 -0.7761 -1.0 3087941 TimTec1_006175 COc1ccc(cc1OC)C2NCC3(C)CN2CC(C)C3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I16 compound treatment 39560.0 -12200.0 -0.71 45920.0 -9260.0 -0.7 -0.9967 -1.0 3212353 TimTec1_006176 COc1ccc(OC)c2C(=O)NC(C)(C)Cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I17 compound treatment 20320.0 -31500.0 -1.82 29360.0 -25800.0 -1.95 -2.6713 -0.9994 3087943 TimTec1_006177 Cc1nc(c(C)s1)c2c[nH]c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I18 compound treatment 44440.0 -7350.0 -0.43 50480.0 -4700.0 -0.36 -0.5527 -0.996 1418925 TimTec1_006178 Cc1c(C#N)c(=O)n(nc1C(=O)NN)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I19 compound treatment 40880.0 -10900.0 -0.63 41040.0 -14100.0 -1.07 -1.2038 -0.9685 3087945 TimTec1_006179 CCOc1cc(NC(=O)c2ccc(OC)cc2)c(C#N)cc1OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I20 compound treatment 49440.0 -2350.0 -0.14 53040.0 -2140.0 -0.16 -0.2109 -0.9963 3212354 TimTec1_006180 OC(=O)c1cc2nc(cc(n2n1)C(F)(F)F)C3CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I21 compound treatment 28520.0 -23300.0 -1.35 37600.0 -17600.0 -1.33 -1.8943 -1.0 3212355 TimTec1_006181 CCOC(=O)c1c(C)nc2-c3ccccc3C(=O)c2c1c4ccc(OC)c(OC)c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I22 compound treatment 33080.0 -18700.0 -1.08 30960.0 -24200.0 -1.83 -2.0629 -0.9686 3087948 TimTec1_006182 Cc1nn(C(=O)c2ccc(cc2)C(C)(C)C)c(N)c1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I23 mock treatment 50880.0 -913.0 -0.05 51120.0 -4060.0 -0.31 -0.2546 -0.8168 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 I24 mock treatment 47720.0 -4070.0 -0.24 49480.0 -5700.0 -0.43 -0.4719 -0.9597 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J01 compound treatment 35200.0 -16600.0 -0.96 49560.0 -5620.0 -0.43 -0.9805 -0.9327 3212356 TimTec1_006183 O=c1[nH]c2ccc(cc2s1)S(=O)(=O)N3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J02 compound treatment 47280.0 -4510.0 -0.26 50880.0 -4300.0 -0.33 -0.415 -0.9941 3087950 TimTec1_006184 CCn1cc(C(=O)O)c(=O)c2cc(F)c(cc12)N3CCN(CC3)C(=S)NC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J03 compound treatment 45360.0 -6430.0 -0.37 49920.0 -5260.0 -0.4 -0.545 -0.9995 3212357 TimTec1_006185 Nn1c(S)nnc1C(O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J04 compound treatment 31280.0 -20500.0 -1.19 36520.0 -18700.0 -1.41 -1.839 -0.9963 3212416 TimTec1_006186 Cc1ccc(NC(=O)NC(NC(=O)Cc2ccccc2)(C(F)(F)F)C(F)(F)F)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J05 compound treatment 38360.0 -13400.0 -0.78 44240.0 -10900.0 -0.83 -1.1358 -0.9995 3087952 TimTec1_006187 Cc1ccc(o1)C(=O)CSc2nnc(c3cccs3)n2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J06 compound treatment 32720.0 -19100.0 -1.11 41800.0 -13400.0 -1.01 -1.4974 -0.9991 1171228 TimTec1_006188 CN(CCc1ccccn1)C(=S)Nc2ccc(Cl)cc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J07 compound treatment 39800.0 -12000.0 -0.69 44080.0 -11100.0 -0.84 -1.0854 -0.9955 3087954 TimTec1_006189 CN(C)c1ccc(cc1)C(N2CCOCC2)P(=O)(c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J08 compound treatment 9720.0 -42100.0 -2.44 13800.0 -41400.0 -3.13 -3.9384 -0.9923 3212417 TimTec1_006190 CC(C)C1OC(OCC1(C)C)c2cccc(NC(=O)c3ccc(F)cc3)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J09 compound treatment 16720.0 -35100.0 -2.03 16720.0 -38500.0 -2.91 -3.4953 -0.9846 3212418 TimTec1_006191 CCOc1ccc(CCNC2=C(C(=O)CC)C(=O)CC(C2)c3ccccc3)cc1OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J10 compound treatment 36680.0 -15100.0 -0.88 46000.0 -9180.0 -0.69 -1.1104 -0.9934 3087957 TimTec1_006192 Cc1nc(SCC(=O)NCc2ccc(Cl)cc2)c(C#N)c(C)c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J11 compound treatment 19600.0 -32200.0 -1.87 19520.0 -35700.0 -2.7 -3.2275 -0.9837 3212419 TimTec1_006193 CCC(CC)NS(=O)(=O)c1cccc(c1)C(=O)NCCOc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J12 compound treatment 39000.0 -12800.0 -0.74 45120.0 -10100.0 -0.76 -1.0625 -0.9999 3087958 TimTec1_006194 NC(Cn1ccnc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J13 compound treatment 32320.0 -19500.0 -1.13 41600.0 -13600.0 -1.03 -1.5245 -0.9989 3087960 TimTec1_006195 Cc1cc(Cl)nc(Cl)c1C(=O)NC(=O)NC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J14 compound treatment 36960.0 -14800.0 -0.86 43880.0 -11300.0 -0.86 -1.2124 -1.0 3212420 TimTec1_006196 Cc1ccc(NC(=S)Nc2ccc(cc2)N3CCOCC3)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J15 compound treatment 37040.0 -14800.0 -0.85 47120.0 -8060.0 -0.61 -1.0357 -0.9863 3212421 TimTec1_006197 Cc1nc2cccc(C(=O)N3CCN(CC3)c4ccccc4)c2o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J16 compound treatment 34080.0 -17700.0 -1.03 42400.0 -12800.0 -0.97 -1.4096 -0.9996 3087985 TimTec1_006198 COc1ccc(OCc2nc(N)nc(Nc3ccc(C)cc3)n2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J17 compound treatment 19360.0 -32400.0 -1.88 18320.0 -36900.0 -2.79 -3.3015 -0.9815 3212422 TimTec1_006199 CC(C)OC(=O)C1CC=CCC1C(=O)NCCc2c(C)[nH]c3ccc(OC(F)(F)F)cc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J18 compound treatment 43560.0 -8230.0 -0.48 51040.0 -4140.0 -0.31 -0.5588 -0.9792 3087987 TimTec1_006200 Cc1cc(nn1CC(=O)Nc2ccc(CC#N)cc2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J19 compound treatment 41040.0 -10800.0 -0.62 50600.0 -4580.0 -0.35 -0.6856 -0.9617 3212423 TimTec1_006201 CCc1nc(N2CCc3ccccc23)c4sc(=S)n(c5ccccc5)c4n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J20 compound treatment 17680.0 -34100.0 -1.98 22160.0 -33000.0 -2.5 -3.1648 -0.9932 3212424 TimTec1_006202 Cc1cc(C=C2C(=O)OC(C)(OC2=O)C(C)(C)C)c(C)n1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J21 compound treatment 44360.0 -7430.0 -0.43 47000.0 -8180.0 -0.62 -0.7423 -0.9843 3087990 TimTec1_006203 COc1ccc(cc1)C2(CNC(=O)c3ccco3)CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J22 compound treatment 49120.0 -2670.0 -0.15 49440.0 -5740.0 -0.43 -0.4166 -0.9035 3212425 TimTec1_006204 OC(=O)CC(C(=O)O)c1ccc(F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J23 mock treatment 45000.0 -6790.0 -0.39 47760.0 -7420.0 -0.56 -0.6754 -0.9849 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 J24 mock treatment 40680.0 -11100.0 -0.64 48880.0 -6300.0 -0.48 -0.7924 -0.9891 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K01 compound treatment 1720.0 -50100.0 -2.9 1360.0 -53800.0 -4.07 -4.932 -0.9862 3087991 TimTec1_006205 CC1CCc2nc(SC3CC(=O)C4OCC3O4)nc(c2C1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K02 compound treatment 47600.0 -4190.0 -0.24 41440.0 -13700.0 -1.04 -0.9071 -0.8494 3212426 TimTec1_006206 CCOC(=O)Cc1nnc(NC(=O)C(CC)Sc2nnc3c4ccccc4n(C)c3n2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K03 compound treatment 28880.0 -22900.0 -1.33 31080.0 -24100.0 -1.82 -2.2285 -0.9878 3087993 TimTec1_006207 C=CCNC(=O)c1scc2OCCOc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K04 compound treatment 24440.0 -27400.0 -1.58 23040.0 -32100.0 -2.43 -2.8408 -0.9784 3212427 TimTec1_006208 Brc1cccc(c1)C2CC(=O)Oc3c2c(=O)oc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K05 compound treatment 23560.0 -28200.0 -1.64 30200.0 -25000.0 -1.89 -2.4936 -0.9974 3087996 TimTec1_006209 CC(C)COC(=O)n1n[n+]([O-])c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K06 compound treatment 18480.0 -33300.0 -1.93 22880.0 -32300.0 -2.44 -3.0935 -0.9931 3212428 TimTec1_006210 COc1ccccc1n2c(cn3c2nc4n(C)c(=O)n(C)c(=O)c43)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K07 compound treatment 34200.0 -17600.0 -1.02 34040.0 -21100.0 -1.6 -1.8522 -0.9763 3087998 TimTec1_006211 O=C(NCc1ccco1)c2scc3OCCOc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K08 compound treatment 38840.0 -13000.0 -0.75 42240.0 -12900.0 -0.98 -1.2232 -0.9914 3212429 TimTec1_006212 OC(=O)CCN1C(=O)c2ccncc2C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K09 compound treatment 6040.0 -45800.0 -2.65 6600.0 -48600.0 -3.68 -4.4745 -0.9871 3088000 TimTec1_006213 CC1(C)OC(C)(C)/C(=C/c2c(Cl)cccc2Cl)/C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K10 compound treatment 29440.0 -22400.0 -1.3 39040.0 -16100.0 -1.22 -1.7796 -0.9996 1872861 TimTec1_006214 CC(=O)N(CCc1ccc(C)[n+]([O-])c1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K11 compound treatment 26600.0 -25200.0 -1.46 26440.0 -28700.0 -2.18 -2.5703 -0.9812 3212430 TimTec1_006215 CN(C(=O)c1cc2nc(cc(n2n1)C(F)(F)F)c3ccco3)c4ccc(OC(F)(F)F)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K12 compound treatment 38360.0 -13400.0 -0.78 42080.0 -13100.0 -0.99 -1.2514 -0.9928 3088002 TimTec1_006216 OCCN1CCN(CC1)c2c(c3ccccc3)c4cc(Cl)ccc4[nH]c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K13 compound treatment 32120.0 -19700.0 -1.14 44120.0 -11100.0 -0.84 -1.3979 -0.9885 3212431 TimTec1_006217 CC1CN(C)C(C)CC1n2nc(O)cc2N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K14 compound treatment 21760.0 -30000.0 -1.74 20160.0 -35000.0 -2.65 -3.1047 -0.9792 3088004 TimTec1_006218 OC1(CCCCC1)C(=O)/C=C/c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K15 compound treatment 9560.0 -42200.0 -2.45 11120.0 -44100.0 -3.33 -4.0884 -0.9884 3212432 TimTec1_006219 CC1CCCC(C)N1C(=O)c2scc3OCCOc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K16 compound treatment 23080.0 -28700.0 -1.66 28120.0 -27100.0 -2.05 -2.6246 -0.9947 3212433 TimTec1_006220 FC(F)(F)c1ccc(cc1)C(=O)Nc2ccccc2NC(=O)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K17 compound treatment 27040.0 -24800.0 -1.43 33080.0 -22100.0 -1.67 -2.1969 -0.9971 1594831 TimTec1_006221 c1[nH]c2ccccc2c1c3csc(n3)c4ccncc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K18 compound treatment 32040.0 -19800.0 -1.14 41880.0 -13300.0 -1.01 -1.521 -0.998 3212434 TimTec1_006222 CC(C)Nc1nc(nc(n1)N2CC3CC(C2)c4cccc(=O)n4C3)N5CCCC5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K19 compound treatment 32880.0 -18900.0 -1.1 38640.0 -16500.0 -1.25 -1.66 -0.9978 3212435 TimTec1_006223 CCOc1nc(NC(=O)NC(=O)c2cccs2)nc(n1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K20 compound treatment 37600.0 -14200.0 -0.82 44640.0 -10500.0 -0.8 -1.1455 -0.9999 3088048 TimTec1_006224 CC1C(C)C(=O)CCN1C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K21 compound treatment 9480.0 -42300.0 -2.45 8240.0 -46900.0 -3.55 -4.2458 -0.9836 3212436 TimTec1_006225 O=C(NCCc1nc(cs1)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K22 compound treatment 31120.0 -20700.0 -1.2 35400.0 -19800.0 -1.5 -1.9056 -0.9939 3088051 TimTec1_006226 Fc1ccccc1/C=C(\C#N)/c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K23 mock treatment 46520.0 -5270.0 -0.31 47000.0 -8180.0 -0.62 -0.6538 -0.947 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 K24 mock treatment 43080.0 -8710.0 -0.5 41240.0 -13900.0 -1.06 -1.103 -0.943 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L01 compound treatment 28360.0 -23400.0 -1.36 26840.0 -28300.0 -2.15 -2.4768 -0.9756 3212437 TimTec1_006227 O=C(Nc1ccc2n(cnc2c1)C3CCCCC3)c4cc5ccccc5o4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L02 compound treatment 45000.0 -6790.0 -0.39 49680.0 -5500.0 -0.42 -0.5726 -0.9996 3088053 TimTec1_006228 O=C1CCCN1CCc2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L03 compound treatment 41480.0 -10300.0 -0.6 47480.0 -7700.0 -0.58 -0.8346 -0.9999 3212438 TimTec1_006229 Cc1cccc(NC(=O)c2ccccc2N)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L04 compound treatment 37960.0 -13800.0 -0.8 41240.0 -13900.0 -1.06 -1.3127 -0.9908 3212439 TimTec1_006230 CC1(C)CC(=O)C2=C(C1)N(C(=O)CC2c3cccs3)c4ccccc4C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L05 compound treatment 34840.0 -17000.0 -0.98 44480.0 -10700.0 -0.81 -1.2672 -0.9954 3088056 TimTec1_006231 Oc1ccc(cc1)c2cnc3ccncc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L06 compound treatment 43280.0 -8510.0 -0.49 44800.0 -10400.0 -0.79 -0.9043 -0.9748 1621990 TimTec1_006232 COc1cccc(NC(=S)N(C)C2CCN(C)CC2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L07 compound treatment 25120.0 -26700.0 -1.55 32480.0 -22700.0 -1.72 -2.3077 -0.9986 3212440 TimTec1_006233 CN(c1ccccc1N(C)S(=O)(=O)c2ccccc2)S(=O)(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L08 compound treatment 44080.0 -7710.0 -0.45 44120.0 -11100.0 -0.84 -0.9079 -0.9568 3212441 TimTec1_006234 O=C1CC(CN1)c2ccc(cc2)S(=O)(=O)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L09 compound treatment 39520.0 -12300.0 -0.71 43760.0 -11400.0 -0.86 -1.114 -0.9953 3088059 TimTec1_006235 Fc1ccc(cc1)N2C(=O)CC(C3=C2CCCC3=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L10 compound treatment 29680.0 -22100.0 -1.28 32760.0 -22400.0 -1.7 -2.1058 -0.9904 3212442 TimTec1_006236 Cc1cc(Cl)nc(Cl)c1C(=O)NC(=O)NCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L11 compound treatment 12520.0 -39300.0 -2.28 19080.0 -36100.0 -2.73 -3.5411 -0.9959 3088060 TimTec1_006237 CC(=O)N1CCc2[nH]c3ccc(C)cc3c2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L12 compound treatment 38360.0 -13400.0 -0.78 48400.0 -6780.0 -0.51 -0.9131 -0.9796 3212739 TimTec1_006238 COc1ccc(/C=N/N2CCOCC2)cc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L13 compound treatment 13520.0 -38300.0 -2.22 18160.0 -37000.0 -2.8 -3.5493 -0.9933 1849557 TimTec1_006239 Nc1c(sc2sc(C(=O)Nc3ccccc3)c(N)c12)C(=O)Nc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L14 compound treatment 44040.0 -7750.0 -0.45 48080.0 -7100.0 -0.54 -0.6976 -0.996 3088062 TimTec1_006240 CC1CCc2c(C1)sc3nc(SCc4nc5ccccc5nc4C)n(C)c(=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L15 compound treatment 41960.0 -9830.0 -0.57 46360.0 -8820.0 -0.67 -0.8748 -0.9969 3212740 TimTec1_006241 CCC1C(N(C2=C(C(=O)CC(C)(C)C2)C1=O)c3ccc(OC)cc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L16 compound treatment 42440.0 -9350.0 -0.54 43400.0 -11800.0 -0.89 -1.0136 -0.9715 3088064 TimTec1_006242 CC1=Nc2ccccc2N=C(NC(=O)CSC(=S)N3CCCCC3)C1c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L17 compound treatment 35640.0 -16200.0 -0.94 38720.0 -16500.0 -1.25 -1.5427 -0.9901 3212741 TimTec1_006243 S=c1sc2c(ncnc2n1c3ccccc3)N4CCN(C/C=C/c5ccccc5)CC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L18 compound treatment 33560.0 -18200.0 -1.06 39320.0 -15900.0 -1.2 -1.5958 -0.998 3212742 TimTec1_006244 C=CCNc1nc(nc(n1)n2ccnc2)N(c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L19 compound treatment 46320.0 -5470.0 -0.32 49000.0 -6180.0 -0.47 -0.5549 -0.9821 3088067 TimTec1_006245 COc1ccc(cc1OC)S(=O)(=O)N(C)CC(=O)NCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L20 compound treatment 41840.0 -9950.0 -0.58 46240.0 -8940.0 -0.68 -0.8862 -0.9968 3212743 TimTec1_006246 CCC1CCCCN1C(=S)NCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L21 compound treatment 43000.0 -8790.0 -0.51 43560.0 -11600.0 -0.88 -0.9821 -0.9663 3088068 TimTec1_006247 COc1ccc(cc1)C2(CNS(=O)(=O)c3ccc(C)cc3)CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L22 compound treatment 45080.0 -6710.0 -0.39 52320.0 -2860.0 -0.22 -0.428 -0.9617 3212744 TimTec1_006248 COc1cc(OC)c(cc1OC)C(=O)N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L23 mock treatment 56200.0 4410.0 0.26 53360.0 -1820.0 -0.14 0.0832 0.2869 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 L24 mock treatment 51840.0 47.5 0.0 50600.0 -4580.0 -0.35 -0.2431 -0.7015 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M01 compound treatment 49880.0 -1910.0 -0.11 54480.0 -699.0 -0.05 -0.1158 -0.9427 3212745 TimTec1_006249 NC(=O)CCN1C(=O)C2C3CC(C=C3)C2C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M02 compound treatment 44240.0 -7550.0 -0.44 45240.0 -9940.0 -0.75 -0.8414 -0.9668 1680974 TimTec1_006250 OC(=O)CCc1ccc([nH]1)c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M03 compound treatment 30560.0 -21200.0 -1.23 34400.0 -20800.0 -1.57 -1.982 -0.9926 1682582 TimTec1_006251 COc1ccc(cc1OC)C2(CCCC2)C(=O)NC3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M04 compound treatment 38520.0 -13300.0 -0.77 38080.0 -17100.0 -1.29 -1.4589 -0.9691 1457689 TimTec1_006252 CC(=O)Nc1nonc1NC(=O)CSc2ncccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M05 compound treatment 31040.0 -20800.0 -1.2 32960.0 -22200.0 -1.68 -2.0394 -0.9865 1008263 TimTec1_006253 O=C(Nc1ccccc1)Nc2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M06 compound treatment 35280.0 -16500.0 -0.96 39640.0 -15500.0 -1.18 -1.5082 -0.9947 3212746 TimTec1_006254 CCC1(CN(CC2(CC)CN(C1)C(=O)c3ccc(OC)cc3)C(=O)c4ccc(OC)cc4)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M07 compound treatment 41560.0 -10200.0 -0.59 46880.0 -8300.0 -0.63 -0.8634 -0.9996 3088136 TimTec1_006255 Nc1n/c(=N\c2ccccc2)/n3c4ccccc4sc3n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M08 compound treatment 30440.0 -21400.0 -1.24 33400.0 -21800.0 -1.65 -2.0405 -0.99 1134094 TimTec1_006256 O=c1[nH]c2ccccc2n1CCOc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M09 compound treatment 35720.0 -16100.0 -0.93 41240.0 -13900.0 -1.06 -1.4045 -0.9981 3088138 TimTec1_006257 NC(=O)CN(Cc1ccccc1F)S(=O)(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M10 compound treatment 35360.0 -16400.0 -0.95 38320.0 -16900.0 -1.28 -1.5756 -0.9896 3212747 TimTec1_006258 CC1(C)Cc2ccccc2C(=N1)CSc3nnc4c5ccccc5[nH]c4n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M11 compound treatment 40480.0 -11300.0 -0.66 48880.0 -6300.0 -0.48 -0.8006 -0.9878 3212748 TimTec1_006259 FC(F)(F)c1cc(nc2cc(nn12)C(=O)OCC3CCCN4CCCCC34)c5ccco5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M12 compound treatment 43360.0 -8430.0 -0.49 38720.0 -16500.0 -1.25 -1.2264 -0.9165 3088141 TimTec1_006260 CC1(C)CC(=O)c2c(n[nH]c2C1)c3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M13 compound treatment 29800.0 -22000.0 -1.27 36000.0 -19200.0 -1.45 -1.9275 -0.9979 3212749 TimTec1_006261 COc1cc(Br)cc2cc(C(=O)N3CCN(CC3)c4cc(C)ccc4C)c(=O)oc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M14 compound treatment 37000.0 -14800.0 -0.86 37800.0 -17400.0 -1.32 -1.5362 -0.9785 3088143 TimTec1_006262 Clc1ccc(cc1)N2Cc3ccccc3OCC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M15 compound treatment 29920.0 -21900.0 -1.27 27640.0 -27500.0 -2.08 -2.3701 -0.9715 3212750 TimTec1_006263 Cc1cc(C)c2c(N)c(sc2n1)C3=NC(C)(C)Cc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M16 compound treatment 34320.0 -17500.0 -1.01 41080.0 -14100.0 -1.07 -1.4704 -0.9997 3088145 TimTec1_006264 Brc1ccc(cc1)C23OC(=O)C4(CCCC4)C3OC(=O)C52CCCC5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M17 compound treatment 40920.0 -10900.0 -0.63 39200.0 -16000.0 -1.21 -1.3007 -0.9538 3212751 TimTec1_006265 Cc1cc2nc(SCCOC(=O)Nc3ccc(Cl)cc3)nc(C)c2cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M18 compound treatment 35160.0 -16600.0 -0.96 38400.0 -16800.0 -1.27 -1.5795 -0.9907 3088147 TimTec1_006266 Cc1ccc(cc1C)N2CCN(CC2)C(=O)C(c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M19 compound treatment 880.0 -50900.0 -2.95 880.0 -54300.0 -4.11 -4.9921 -0.9868 3212752 TimTec1_006267 O=C1CC(C2COC1O2)n3nnnc3c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M20 compound treatment 50080.0 -1710.0 -0.1 54640.0 -539.0 -0.04 -0.099 -0.9228 3212753 TimTec1_006268 Nc1ccc(cc1)C(O)C(O)CO 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M21 compound treatment 43280.0 -8510.0 -0.49 49520.0 -5660.0 -0.43 -0.6516 -0.9975 3212754 TimTec1_006269 CCCCN1C(=O)C2C(NC(C)(C2C1=O)C(=O)O)c3ccccc3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M22 compound treatment 3280.0 -48500.0 -2.81 4280.0 -50900.0 -3.85 -4.7118 -0.988 3088149 TimTec1_006270 CCOc1cc2CNC(c3cccn3-c2cc1OCC)c4cc(C)c(OC)cc4C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M23 mock treatment 46120.0 -5670.0 -0.33 53240.0 -1940.0 -0.15 -0.3362 -0.934 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 M24 mock treatment 52120.0 328.0 0.02 54920.0 -259.0 -0.02 -4.0E-4 -0.0159 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N01 compound treatment 44040.0 -7750.0 -0.45 52080.0 -3100.0 -0.23 -0.4835 -0.9541 3212755 TimTec1_006271 CC(C)(C)c1ccc(CNC(=O)C2CCCN2C(=O)Nc3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N02 compound treatment 39360.0 -12400.0 -0.72 47800.0 -7380.0 -0.56 -0.9043 -0.9921 1352036 TimTec1_006272 CNC(=O)C1Cc2ccccc2CN1S(=O)(=O)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N03 compound treatment 35960.0 -15800.0 -0.92 38400.0 -16800.0 -1.27 -1.5467 -0.9872 3212756 TimTec1_006273 Clc1ccccc1CS(=O)(=O)N2CCN(Cc3ccc4OCOc4c3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N04 compound treatment 2200.0 -49600.0 -2.87 4040.0 -51100.0 -3.87 -4.7689 -0.9892 3212757 TimTec1_006274 Cc1cc(Cl)ccc1OCC(=O)NCC2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N05 compound treatment 32680.0 -19100.0 -1.11 44240.0 -10900.0 -0.83 -1.3685 -0.9897 1090623 TimTec1_006275 COC(=O)c1ccc(cc1)S(=O)(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N06 compound treatment 30840.0 -21000.0 -1.21 36360.0 -18800.0 -1.42 -1.8656 -0.9968 3088153 TimTec1_006276 CCN(C1CCCCC1)C(=S)NCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N07 compound treatment 5560.0 -46200.0 -2.68 8120.0 -47100.0 -3.56 -4.4128 -0.9901 3212758 TimTec1_006277 CSc1nc2ccc(cc2s1)S(=O)(=O)N3CCc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N08 compound treatment 36120.0 -15700.0 -0.91 38240.0 -16900.0 -1.28 -1.5487 -0.9857 3088155 TimTec1_006278 Clc1cccc(c1)n2c(=O)n3CCCn3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N09 compound treatment 33320.0 -18500.0 -1.07 38480.0 -16700.0 -1.26 -1.6506 -0.9966 3212759 TimTec1_006279 COC(=O)c1ccc(NC(=O)CSc2nc(=O)cc(N)n2CCc3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N10 compound treatment 4280.0 -47500.0 -2.75 4120.0 -51100.0 -3.86 -4.6794 -0.9862 3088223 TimTec1_006280 FC(F)(F)c1ccccc1C2NCc3ccccc3-n4cccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N11 compound treatment 37000.0 -14800.0 -0.86 39320.0 -15900.0 -1.2 -1.4548 -0.9864 3212760 TimTec1_006281 COc1ccc(cc1OC)C2NC(=O)C(=C(S)N2c3ccccc3)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N12 compound treatment 27920.0 -23900.0 -1.38 30640.0 -24500.0 -1.86 -2.2914 -0.9895 3088227 TimTec1_006282 CCC(=O)Nc1cccc(Oc2nc(C)cc(C)c2C#N)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N13 compound treatment 41280.0 -10500.0 -0.61 42760.0 -12400.0 -0.94 -1.0954 -0.9779 3212761 TimTec1_006283 FC(F)(F)C(=O)Nc1c(nnn1Cc2ccccc2)C(=O)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N14 compound treatment 43160.0 -8630.0 -0.5 42720.0 -12500.0 -0.94 -1.0205 -0.956 3212762 TimTec1_006284 CN1C2=C(C(NC1=O)c3ccccc3)C(=O)N(CCc4ccccc4)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N15 compound treatment 36280.0 -15500.0 -0.9 43400.0 -11800.0 -0.89 -1.266 -1.0 3088229 TimTec1_006285 COc1cc2nc(NC(=N)N)nc(O)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N16 compound treatment 26440.0 -25400.0 -1.47 28600.0 -26600.0 -2.01 -2.4612 -0.988 3088230 TimTec1_006286 CCOC(=O)c1c(NC2=CC(=O)CCC2)sc3CCCCCc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N17 compound treatment 22840.0 -29000.0 -1.68 22480.0 -32700.0 -2.48 -2.9363 -0.982 3212763 TimTec1_006287 Brc1ccc(cc1)C2N(C(=O)C32CCCCC3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N18 compound treatment 21040.0 -30800.0 -1.78 17320.0 -37900.0 -2.87 -3.2862 -0.9739 3212827 TimTec1_006288 COc1ccc(/C=C/C(=O)C2(O)CCCCC2)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N19 compound treatment 11560.0 -40200.0 -2.33 14760.0 -40400.0 -3.06 -3.8116 -0.991 3088233 TimTec1_006289 Fc1cnc(Nc2ccccc2)nc1N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N20 compound treatment 41880.0 -9910.0 -0.57 43080.0 -12100.0 -0.92 -1.0537 -0.9747 3212828 TimTec1_006290 O=C1CC(CN1)c2ccc(cc2)S(=O)(=O)NC3CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N21 compound treatment 43040.0 -8750.0 -0.51 48040.0 -7140.0 -0.54 -0.7407 -0.9995 3088235 TimTec1_006291 COc1ccccc1NC(=O)C2CC(=O)OC32CCOC(C)(C)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N22 compound treatment 37880.0 -13900.0 -0.81 36640.0 -18500.0 -1.4 -1.5622 -0.9654 3212829 TimTec1_006292 COC(=O)N1CCN(CC1)c2nc(cs2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N23 mock treatment 44800.0 -6990.0 -0.41 52480.0 -2700.0 -0.2 -0.4309 -0.9497 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 N24 mock treatment 45000.0 -6790.0 -0.39 49600.0 -5580.0 -0.42 -0.5769 -0.9994 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O01 compound treatment 40960.0 -10800.0 -0.63 47880.0 -7300.0 -0.55 -0.8344 -0.998 3212830 TimTec1_006293 CC1(C)CN2C(N(C(=S)N2C1)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O02 compound treatment 43160.0 -8630.0 -0.5 60440.0 5260.0 0.4 -0.0721 -0.1127 3088238 TimTec1_006294 COC(=O)c1noc(n1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O03 compound treatment 42760.0 -9030.0 -0.52 54200.0 -979.0 -0.07 -0.4224 -0.7992 3088239 TimTec1_006295 CN(C(=O)c1nc2ncccn2n1)c3ccc(OC(F)(F)F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O04 compound treatment 40360.0 -11400.0 -0.66 43440.0 -11700.0 -0.89 -1.0967 -0.9895 3212831 TimTec1_006296 CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1Oc2ccc(Cl)cc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O05 compound treatment 38520.0 -13300.0 -0.77 47800.0 -7380.0 -0.56 -0.9387 -0.9877 3212832 TimTec1_006297 COC(=O)CC/1=NN(C(=O)\C1=C(\C)/O)c2nc3ccccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O06 compound treatment 47600.0 -4190.0 -0.24 51600.0 -3580.0 -0.27 -0.3633 -0.9985 3088242 TimTec1_006298 Sc1nnc(c2ccco2)n1Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O07 compound treatment 50200.0 -1590.0 -0.09 48760.0 -6420.0 -0.49 -0.4088 -0.8266 3088243 TimTec1_006299 CC1(C)OC(=NC1=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O08 compound treatment 14280.0 -37500.0 -2.17 21320.0 -33900.0 -2.56 -3.3491 -0.9966 3212833 TimTec1_006300 COc1ccc(cc1OC)C(=O)N2CCN(CC2)c3c(C)cccc3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O09 compound treatment 43280.0 -8510.0 -0.49 42240.0 -12900.0 -0.98 -1.0413 -0.9496 3088245 TimTec1_006301 OC(=O)CCc1ccc(o1)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O10 compound treatment 31120.0 -20700.0 -1.2 35680.0 -19500.0 -1.48 -1.8906 -0.9946 3212834 TimTec1_006302 CC(=O)N1CCc2ccccc2C1CNC=C3C(=O)CC(CC3=O)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O11 compound treatment 25880.0 -25900.0 -1.5 30640.0 -24500.0 -1.86 -2.375 -0.9944 3088248 TimTec1_006303 C1Oc2ccc(cc2O1)C3NCc4ccccc4-n5cccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O12 compound treatment 16400.0 -35400.0 -2.05 18200.0 -37000.0 -2.8 -3.4292 -0.9883 3212835 TimTec1_006304 CN(C)c1ccc(cc1)c2n[nH]c3CCCC(=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O13 compound treatment 31920.0 -19900.0 -1.15 36000.0 -19200.0 -1.45 -1.8407 -0.9934 3212836 TimTec1_006305 CCN(C1CCCCC1)C(=O)c2cc3cc(Br)cc(OC)c3oc2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O14 compound treatment 36760.0 -15000.0 -0.87 38320.0 -16900.0 -1.28 -1.5182 -0.9827 3088319 TimTec1_006306 COc1ccc(NCc2cc3ccccc3[nH]c2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O15 compound treatment 46920.0 -4870.0 -0.28 47880.0 -7300.0 -0.55 -0.5903 -0.9514 3212837 TimTec1_006307 COc1ccc(CNC(=O)c2cc3ccccc3oc2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O16 compound treatment 52560.0 768.0 0.04 46640.0 -8540.0 -0.65 -0.4256 -0.6569 3088323 TimTec1_006308 S=c1n(CN2CCOCC2)nc3CCCCCn31 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O17 compound treatment 21280.0 -30500.0 -1.77 26760.0 -28400.0 -2.15 -2.7711 -0.9953 3212838 TimTec1_006309 CCCNC(=O)Nc1ccc2c(c1)oc3ccccc32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O18 compound treatment 54280.0 2490.0 0.14 54280.0 -899.0 -0.07 0.0538 0.3376 3088325 TimTec1_006310 O=C1N(C2CCCCC2)C(=O)c3cnccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O19 compound treatment 18640.0 -33200.0 -1.92 19080.0 -36100.0 -2.73 -3.2903 -0.9851 3212839 TimTec1_006311 C/C(=C\1/C(=NN(C1=O)c2nc3ccccc3s2)C)/NCCc4c(C)[nH]c5ccccc45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O20 compound treatment 50760.0 -1030.0 -0.06 54440.0 -739.0 -0.06 -0.0818 -0.9994 3088326 TimTec1_006312 CN(C)C(=O)N1CCNCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O21 compound treatment 7440.0 -44400.0 -2.57 7000.0 -48200.0 -3.65 -4.3958 -0.9853 3088328 TimTec1_006313 CC1(C)OC(C)(C)/C(=C/c2ccc3cccnc3c2)/C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O22 compound treatment 11160.0 -40600.0 -2.35 11400.0 -43800.0 -3.31 -4.0079 -0.986 3212840 TimTec1_006314 N=C1OC23CCCCC3C1(C#N)C(C#N)(C#N)C(O2)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O23 mock treatment 56760.0 4970.0 0.29 53000.0 -2180.0 -0.16 0.0869 0.262 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 O24 mock treatment 63240.0 11400.0 0.66 56480.0 1300.0 0.1 0.5386 0.8033 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P01 compound treatment 29000.0 -22800.0 -1.32 35000.0 -20200.0 -1.53 -2.0138 -0.9974 3088330 TimTec1_006315 CSc1nc2ccc(cc2s1)S(=O)(=O)N3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P02 compound treatment 34280.0 -17500.0 -1.01 38840.0 -16300.0 -1.24 -1.592 -0.9952 1180888 TimTec1_006316 O=C(C1Cc2ccccc2CN1S(=O)(=O)c3cccs3)N4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P03 compound treatment 43680.0 -8110.0 -0.47 45840.0 -9340.0 -0.71 -0.8322 -0.9803 3212841 TimTec1_006317 Fc1cc(Cl)c(cc1F)C(=O)Nc2cc(cc(c2)C(=O)N3CCOCC3)C(=O)N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P04 compound treatment 32200.0 -19600.0 -1.14 39920.0 -15300.0 -1.16 -1.6194 -1.0 3088333 TimTec1_006318 CN(CC(=O)Nc1ccc(NC(=O)C)cc1)S(=O)(=O)c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P05 compound treatment 37640.0 -14200.0 -0.82 41520.0 -13700.0 -1.03 -1.3109 -0.9934 3088334 TimTec1_006319 CCCCS(=O)(=O)Nc1ccc2ncn(C)c(=O)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P06 compound treatment 36080.0 -15700.0 -0.91 39960.0 -15200.0 -1.15 -1.4583 -0.9932 3212842 TimTec1_006320 Cc1cccc(C)c1NC(=S)NC2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P07 compound treatment 39120.0 -12700.0 -0.73 37640.0 -17500.0 -1.33 -1.4579 -0.961 3212843 TimTec1_006321 CCOC(=O)C1=C(N)N2C(=O)C(C)SC2=C(C1c3cccc(OC)c3)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P08 compound treatment 42560.0 -9230.0 -0.53 39920.0 -15300.0 -1.16 -1.1949 -0.9388 3088336 TimTec1_006322 COc1nc(NCC2CCCO2)nc(n1)N3CC4CC(C3)c5cccc(=O)n5C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P09 compound treatment 7640.0 -44200.0 -2.56 8520.0 -46700.0 -3.53 -4.3062 -0.9875 3212844 TimTec1_006323 CCOc1ccc(CCNC(=C2C(=O)CCCC2=O)CC)cc1OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P10 compound treatment 38440.0 -13400.0 -0.77 42280.0 -12900.0 -0.98 -1.2374 -0.9934 3212845 TimTec1_006324 CCc1ccc(cc1)C2Nc3ccccc3NC4=C2C(=O)CC(C)(C)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P11 compound treatment 40280.0 -11500.0 -0.67 40600.0 -14600.0 -1.1 -1.252 -0.9709 3088339 TimTec1_006325 COC(=O)C1C(C)CC2=C(C(Nc3ccccc3N2)c4cccc(Br)c4)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P12 compound treatment 35360.0 -16400.0 -0.95 47800.0 -7380.0 -0.56 -1.0681 -0.9677 3212846 TimTec1_006326 O=C(NCC1(CC2CC3CC(C2)C1)C3)c4nc5ncccn5n4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P13 compound treatment 41680.0 -10100.0 -0.59 45000.0 -10200.0 -0.77 -0.9591 -0.9909 3088341 TimTec1_006327 CC1Cn2c(COc3ccccc3)nnc2S1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P14 compound treatment 32800.0 -19000.0 -1.1 35920.0 -19300.0 -1.46 -1.8089 -0.9904 3212847 TimTec1_006328 CN(C)c1nc(Oc2ccc(=O)n(C)n2)nc(n1)N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P15 compound treatment 44240.0 -7550.0 -0.44 39480.0 -15700.0 -1.19 -1.1497 -0.9079 3088343 TimTec1_006329 CC(C)(C)NC(=O)CSc1nnnn1C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P16 compound treatment 39280.0 -12500.0 -0.72 41080.0 -14100.0 -1.07 -1.2672 -0.9822 1353461 TimTec1_006330 OCC1CCCN(C1)C(=S)NCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P17 compound treatment 21240.0 -30600.0 -1.77 26760.0 -28400.0 -2.15 -2.7728 -0.9953 3088414 TimTec1_006331 C1CCN(C1)c2nc(nc(n2)n3ccnc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P18 compound treatment 39200.0 -12600.0 -0.73 42080.0 -13100.0 -0.99 -1.217 -0.9886 3212848 TimTec1_006332 CCOC(=O)[C@H]1NC(=O)C[C@H]1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P19 compound treatment 25440.0 -26400.0 -1.53 27880.0 -27300.0 -2.07 -2.5408 -0.9889 3088418 TimTec1_006333 COc1ccc(cc1)C2=CC(NC(=S)N2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P20 compound treatment 25640.0 -26200.0 -1.52 28840.0 -26300.0 -1.99 -2.4812 -0.9908 3212849 TimTec1_006334 CCCNC1=C(C(=O)Cc2ccc(OCC)c(OCC)c2)C(=O)CC(C)(C)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P21 compound treatment 42200.0 -9590.0 -0.56 42040.0 -13100.0 -0.99 -1.0962 -0.9622 3212850 TimTec1_006335 O=C1CC(C2=C(CCCC2=O)N1c3ccccc3)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P22 compound treatment 23600.0 -28200.0 -1.63 26400.0 -28800.0 -2.18 -2.6953 -0.9899 3088421 TimTec1_006336 CCn1c(=O)n(CC)c2cc(ccc12)S(=O)(=O)NC3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P23 mock treatment 41440.0 -10400.0 -0.6 48680.0 -6500.0 -0.49 -0.772 -0.9952 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2080 P24 mock treatment 48240.0 -3550.0 -0.21 48200.0 -6980.0 -0.53 -0.5191 -0.9156 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A01 compound treatment 22480.0 -32000.0 -1.85 24800.0 -19400.0 -1.47 -2.349 -0.9935 3212851 TimTec1_006337 NC(=O)C(Cc1ccccc1)NC(=O)C2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A02 compound treatment 8600.0 -45800.0 -2.66 10440.0 -33800.0 -2.56 -3.6863 -0.9998 3088424 TimTec1_006338 CCCc1nc(Sc2nncn2C)c3sc(=S)n(c4ccccc4)c3n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A03 compound treatment 36480.0 -18000.0 -1.04 35160.0 -9070.0 -0.69 -1.221 -0.9796 3212852 TimTec1_006339 Fc1ccc(NC(=O)c2ccccc2NS(=O)(=O)N3CCCC3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A04 compound treatment 51200.0 -3240.0 -0.19 29320.0 -14900.0 -1.13 -0.9305 -0.8134 1402109 TimTec1_006340 Cc1ccc2n3CCN(CCC(=O)N)c4cccc(c2c1)c43 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A05 compound treatment 31800.0 -22600.0 -1.31 29120.0 -15100.0 -1.14 -1.736 -0.9977 3088426 TimTec1_006341 Cc1ccc(cc1CNC(=O)c2ccco2)c3nn(C)c(=O)c4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A06 compound treatment 14200.0 -40200.0 -2.33 12080.0 -32100.0 -2.43 -3.3691 -0.9998 1292864 TimTec1_006342 CCSC1=C(C#N)C(=N)n2c1cc3CCCCc32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A07 compound treatment 18440.0 -36000.0 -2.09 13400.0 -30800.0 -2.33 -3.1247 -0.9984 3088428 TimTec1_006343 Cc1cc2NC(Nc3ccc(F)c(Cl)c3)Sn2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A08 compound treatment 43080.0 -11400.0 -0.66 38000.0 -6230.0 -0.47 -0.7986 -0.9866 3212922 TimTec1_006344 CC(C)(O)C#Cc1ccc(s1)C(=O)NCc2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A09 compound treatment 47920.0 -6520.0 -0.38 38040.0 -6190.0 -0.47 -0.5981 -0.9943 3088430 TimTec1_006345 Cc1cc(c(C)s1)S(=O)(=O)N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A10 compound treatment 41920.0 -12500.0 -0.73 39360.0 -4870.0 -0.37 -0.7733 -0.9507 1848161 TimTec1_006346 Cc1cc(C)c(C#N)c(SCC(=O)NC2CCCCC2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A11 compound treatment 54840.0 404.0 0.02 41400.0 -2830.0 -0.21 -0.1348 -0.6261 3088432 TimTec1_006347 CCNC(=S)N1CCCC(C1)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A12 compound treatment 50600.0 -3840.0 -0.22 42960.0 -1270.0 -0.1 -0.225 -0.9294 3212923 TimTec1_006348 CCOc1ccc(NC(=S)N2CCSC2c3ccc(C#CC(C)(C)O)s3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A13 compound treatment 49360.0 -5080.0 -0.29 42920.0 -1310.0 -0.1 -0.2779 -0.8957 3088434 TimTec1_006349 OC(=O)CCc1cc(Cl)no1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A14 compound treatment 36000.0 -18400.0 -1.07 25240.0 -19000.0 -1.44 -1.7716 -0.9893 3212924 TimTec1_006350 COc1ccc(cc1)c2c(C)c3ccccc3oc2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A15 compound treatment 47800.0 -6640.0 -0.38 36720.0 -7510.0 -0.57 -0.6737 -0.9819 3212925 TimTec1_006351 FC(F)(F)c1ccccc1N2C(=O)CC(C3=C2CCCC3=O)c4cccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A16 compound treatment 34840.0 -19600.0 -1.14 25360.0 -18900.0 -1.43 -1.8127 -0.9935 3088437 TimTec1_006352 CCOc1ccc(cc1)c2cc3ccc(cc3oc2=O)N(CC)CC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A17 compound treatment 42560.0 -11900.0 -0.69 29920.0 -14300.0 -1.08 -1.2523 -0.976 3088438 TimTec1_006353 O=C/1NC(=N\C1=C/c2ccco2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A18 compound treatment 22000.0 -32400.0 -1.88 22840.0 -21400.0 -1.62 -2.4736 -0.9972 3212926 TimTec1_006354 CC(=O)n1c(=O)sc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A19 compound treatment 27040.0 -27400.0 -1.59 19880.0 -24300.0 -1.84 -2.4255 -0.9972 3212927 TimTec1_006355 COc1ccc(cc1)C2OCc3ccccc3N2C(=O)c4cccc(OC)c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A20 compound treatment 12280.0 -42200.0 -2.44 8960.0 -35300.0 -2.67 -3.6147 -0.999 1648398 TimTec1_006356 Oc1ccc2ccccc2c1C(NC(=O)C3CCCCC3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A21 compound treatment 53440.0 -996.0 -0.06 39720.0 -4510.0 -0.34 -0.2821 -0.8151 3088507 TimTec1_006357 CCN(CC)C(=O)Cn1nnc(n1)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A22 compound treatment 30160.0 -24300.0 -1.41 29320.0 -14900.0 -1.13 -1.7925 -0.994 1222563 TimTec1_006358 CC(Oc1ccccc1)C(=O)Nc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A23 mock treatment 58080.0 3640.0 0.21 53920.0 9690.0 0.73 0.6681 0.8751 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 A24 mock treatment 69200.0 14800.0 0.86 48120.0 3890.0 0.29 0.8132 0.8988 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B01 compound treatment 35600.0 -18800.0 -1.09 33000.0 -11200.0 -0.85 -1.3726 -0.9924 1265521 TimTec1_006359 O=C(CCc1ccccc1)c2ccc3OCCCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B02 compound treatment 25360.0 -29100.0 -1.68 32880.0 -11300.0 -0.86 -1.7986 -0.9511 1216112 TimTec1_006360 Cc1nn(c2CC3C(c12)C3(C)C)c4ccccn4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B03 compound treatment 41440.0 -13000.0 -0.75 40280.0 -3950.0 -0.3 -0.7437 -0.9181 1782446 TimTec1_006361 NC(=C(C#N)C#N)/C(=C/c1c[nH]c2ccccc12)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B04 compound treatment 20720.0 -33700.0 -1.95 20440.0 -23800.0 -1.8 -2.6545 -0.9992 1431158 TimTec1_006362 CCN(CC)c1ccc2c(cc(=O)oc2c1)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B05 compound treatment 24160.0 -30300.0 -1.75 20280.0 -23900.0 -1.81 -2.5221 -0.9999 1471466 TimTec1_006363 COc1ccc2[nH]c3C(=O)NC(C)Cc3c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B06 compound treatment 17160.0 -37300.0 -2.16 11560.0 -32700.0 -2.47 -3.2756 -0.9977 1510603 TimTec1_006364 COc1ccc(CNc2ccc(C)c(C)c2)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B07 compound treatment 39240.0 -15200.0 -0.88 35960.0 -8270.0 -0.63 -1.0651 -0.986 1598446 TimTec1_006365 Brc1ccc(NC(=O)C2(CCCC2)c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B08 compound treatment 48320.0 -6120.0 -0.35 42800.0 -1430.0 -0.11 -0.327 -0.8826 1697979 TimTec1_006366 O=C(Nc1ccccc1)C2CC3c4ccccc4C2c5ccccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B09 compound treatment 55360.0 924.0 0.05 50520.0 6290.0 0.48 0.3746 0.7816 1393320 TimTec1_006367 OC(=O)CC(Cc1ccc(Cl)cc1)C(=O)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B10 compound treatment 43280.0 -11200.0 -0.65 31680.0 -12500.0 -0.95 -1.1286 -0.9824 1217422 TimTec1_006368 CCOC(=O)c1c(NC(=O)c2ccc(OC)cc2)sc3CCC(C)Cc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B11 compound treatment 58600.0 4160.0 0.24 45680.0 1450.0 0.11 0.2483 0.9367 3088515 TimTec1_006369 OC(=O)/C(=C\c1cccs1)/c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B12 compound treatment 29600.0 -24800.0 -1.44 24160.0 -20100.0 -1.52 -2.0916 -0.9996 1183980 TimTec1_006370 CN1C(C(=C(O)C1=O)C(=O)c2ccc(C)cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B13 compound treatment 51120.0 -3320.0 -0.19 38400.0 -5830.0 -0.44 -0.4478 -0.9307 1620531 TimTec1_006371 CCc1nc(N)c(C#N)c(c1C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B14 compound treatment 12800.0 -41600.0 -2.41 11800.0 -32400.0 -2.45 -3.4414 -1.0 3212929 TimTec1_006372 CCCCn1c2nc(cn2c3ccccc13)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B15 compound treatment 53440.0 -996.0 -0.06 44440.0 213.0 0.02 -0.0294 -0.4913 1922330 TimTec1_006373 COC(=O)CCS(=O)(=O)c1ccc(Br)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B16 compound treatment 6560.0 -47900.0 -2.77 5680.0 -38500.0 -2.92 -4.0246 -0.9997 3088518 TimTec1_006374 Clc1ccc(cc1)c2cn3ccccc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B17 compound treatment 50440.0 -4000.0 -0.23 42080.0 -2150.0 -0.16 -0.2787 -0.985 1683391 TimTec1_006375 Clc1ccc(cc1Cl)N2Cc3ccccc3C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B18 compound treatment 45360.0 -9080.0 -0.53 42440.0 -1790.0 -0.14 -0.4675 -0.861 1131054 TimTec1_006376 Nc1ccc(C(=O)OCC(=O)c2ccc(Br)cc2)c(O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B19 compound treatment 56800.0 2360.0 0.14 47720.0 3490.0 0.26 0.2838 0.9531 1106472 TimTec1_006377 COC(=O)c1ccc(C)c(c1)N(CCO)CCO 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B20 compound treatment 42800.0 -11600.0 -0.67 39880.0 -4350.0 -0.33 -0.7094 -0.9456 3088521 TimTec1_006378 c1sc(nc1c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B21 compound treatment 42040.0 -12400.0 -0.72 32760.0 -11500.0 -0.87 -1.1216 -0.9956 1414393 TimTec1_006379 COc1cc2CCN(Cc2cc1OC)C(=O)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B22 compound treatment 47120.0 -7320.0 -0.42 43080.0 -1150.0 -0.09 -0.3612 -0.8347 3088523 TimTec1_006380 CC(C)COc1ccc2[nH]c3CCCc3c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B23 mock treatment 64680.0 10200.0 0.59 50240.0 6010.0 0.46 0.7415 0.9914 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 B24 mock treatment 54600.0 164.0 0.01 51240.0 7010.0 0.53 0.382 0.7196 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C01 compound treatment 43280.0 -11200.0 -0.65 37560.0 -6670.0 -0.5 -0.8139 -0.9925 3212930 TimTec1_006381 CCn1c(=O)n(CC)c2cc(ccc12)S(=O)(=O)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C02 compound treatment 50600.0 -3840.0 -0.22 49640.0 5410.0 0.41 0.1325 0.2843 3088525 TimTec1_006382 CC1(C)OC(=O)N(CC(=O)Nc2ccc(F)cc2)C1(C)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C03 compound treatment 31000.0 -23400.0 -1.36 34040.0 -10200.0 -0.77 -1.5054 -0.9641 3212931 TimTec1_006383 Fc1ccc(cc1)c2cn3c(c(nc3[nH]2)c4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C04 compound treatment 50080.0 -4360.0 -0.25 45640.0 1410.0 0.11 -0.1029 -0.3753 3212932 TimTec1_006384 COCC(=O)Nc1ccc(CC#N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C05 compound treatment 32440.0 -22000.0 -1.27 26720.0 -17500.0 -1.33 -1.8382 -0.9998 3212933 TimTec1_006385 Cc1ccc(cc1)c2nn(CC(=O)Nc3cccnc3)c(=O)c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C06 compound treatment 47520.0 -6920.0 -0.4 40040.0 -4190.0 -0.32 -0.5075 -0.9933 3087470 TimTec1_006386 CC1CN(CC(C)O1)C(=O)c2scc3OCCOc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C07 compound treatment 46320.0 -8120.0 -0.47 42080.0 -2150.0 -0.16 -0.4475 -0.8993 3212934 TimTec1_006387 O=C(OCc1ccccc1)c2cccc(c2)c3nnn(Cc4ccccc4)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C08 compound treatment 2320.0 -52100.0 -3.02 2280.0 -41900.0 -3.18 -4.3803 -0.9997 3087472 TimTec1_006388 COc1ccc(cc1)C(=O)Oc2c(C)cc(cc2C)C(O)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C09 compound treatment 29760.0 -24700.0 -1.43 28360.0 -15900.0 -1.2 -1.8602 -0.9962 3212935 TimTec1_006389 NC(=O)c1cccc(c1)S(=O)(=O)N2CC(CC2=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C10 compound treatment 57480.0 3040.0 0.18 41360.0 -2870.0 -0.22 -0.0288 -0.1029 3087474 TimTec1_006390 NN(C(=O)N)c1nc(nc(n1)N2CCCCC2)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C11 compound treatment 52880.0 -1560.0 -0.09 43240.0 -988.0 -0.07 -0.1166 -0.9957 3212936 TimTec1_006391 Clc1ccc2[nH]c(=O)c(N3CCCC3)c(c4ccccc4)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C12 compound treatment 50560.0 -3880.0 -0.22 39760.0 -4470.0 -0.34 -0.3979 -0.9802 3212937 TimTec1_006392 CCOC(=O)c1c(N)nn(C(=O)CC)c1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C13 compound treatment 30480.0 -24000.0 -1.39 25840.0 -18400.0 -1.39 -1.9656 -1.0 2103793 TimTec1_006393 COc1ccc(/C=C/C(=O)\C=C\c2ccc(OC)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C14 compound treatment 35320.0 -19100.0 -1.11 30800.0 -13400.0 -1.02 -1.5019 -0.9991 3087477 TimTec1_006394 Cc1ccc2c(C)c(c3ccccc3)c(=O)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C15 compound treatment 56440.0 2000.0 0.12 43560.0 -668.0 -0.05 0.0464 0.3662 3212938 TimTec1_006395 CCOC(=O)C1C(CC(=CC1=O)N2CCOCC2)c3cccc(OC)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C16 compound treatment 54320.0 -116.0 -0.01 41960.0 -2270.0 -0.17 -0.1261 -0.7343 3087479 TimTec1_006396 Cc1c(CC(=O)O)c(=O)oc2c(O)c(O)ccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C17 compound treatment 50520.0 -3920.0 -0.23 41080.0 -3150.0 -0.24 -0.3289 -0.9997 3212939 TimTec1_006397 COc1cc2c(cc1NS(=O)(=O)c3ccc(cc3)N4CCCC4=O)oc5ccccc52 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C18 compound treatment 55080.0 644.0 0.04 43320.0 -908.0 -0.07 -0.0222 -0.284 1047503 TimTec1_006398 OC(=O)c1ccccc1C(=O)c2ccc(Br)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C19 compound treatment 41640.0 -12800.0 -0.74 36240.0 -7990.0 -0.6 -0.9518 -0.9949 3212940 TimTec1_006399 COc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)Nc4cc(OC)c(OC)cc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C20 compound treatment 14280.0 -40200.0 -2.33 11000.0 -33200.0 -2.52 -3.4236 -0.9992 1299646 TimTec1_006400 Cc1ccc(cc1)C(=O)Nc2ccc(Cl)cn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C21 compound treatment 57160.0 2720.0 0.16 50000.0 5770.0 0.44 0.4206 0.9053 3087483 TimTec1_006401 CCN1C(=O)OC(C)(CCc2ccccc2)C1(C)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C22 compound treatment 48200.0 -6240.0 -0.36 39440.0 -4790.0 -0.36 -0.5117 -1.0 1518127 TimTec1_006402 CC(NC(=O)Cc1ccc(Br)cc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C23 mock treatment 56280.0 1840.0 0.11 48440.0 4210.0 0.32 0.301 0.8951 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 C24 mock treatment 67360.0 12900.0 0.75 48520.0 4290.0 0.32 0.7592 0.9301 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D01 compound treatment 16720.0 -37700.0 -2.19 19400.0 -24800.0 -1.88 -2.874 -0.9972 1621697 TimTec1_006403 Clc1ccc(Nc2nc(NCCN3CCOCC3)nc(Nc4ccc(Cl)cc4)n2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D02 compound treatment 32240.0 -22200.0 -1.29 36440.0 -7790.0 -0.59 -1.3262 -0.9374 1652889 TimTec1_006404 CC(C)COc1ccc(cc1)C(O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D03 compound treatment 21600.0 -32800.0 -1.9 23440.0 -20800.0 -1.57 -2.4579 -0.9956 3211230 TimTec1_006405 COc1ccc(/C=N/c2c(nc3ccccn23)c4ccco4)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D04 compound treatment 53560.0 -876.0 -0.05 46160.0 1930.0 0.15 0.0675 0.4362 1434704 TimTec1_006406 OC(=O)c1ccc(CN2CCCCC2)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D05 compound treatment 36520.0 -17900.0 -1.04 30840.0 -13400.0 -1.01 -1.4505 -0.9999 3087486 TimTec1_006407 CCCCc1ccc(NC(=O)C(C)CC)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D06 compound treatment 39480.0 -15000.0 -0.87 31320.0 -12900.0 -0.98 -1.3036 -0.9982 1411188 TimTec1_006408 CCOc1ccc(NC(=O)c2c3CCCCc3nc4ccccc24)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D07 compound treatment 40640.0 -13800.0 -0.8 39480.0 -4750.0 -0.36 -0.8193 -0.9349 1481913 TimTec1_006409 CCOC(=O)C(Cc1ccccc1)C(=O)Nc2ccccc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D08 compound treatment 53920.0 -516.0 -0.03 41000.0 -3230.0 -0.24 -0.1939 -0.7878 3211231 TimTec1_006410 COC(=O)CSc1cc(C)nc(N)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D09 compound treatment 57040.0 2600.0 0.15 44520.0 293.0 0.02 0.1223 0.8023 1332614 TimTec1_006411 CN(C)CCOC(=O)c1sc2ccccc2c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D10 compound treatment 48760.0 -5680.0 -0.33 35800.0 -8430.0 -0.64 -0.6836 -0.9525 1699312 TimTec1_006412 CC(=O)Nc1sc2CCCCCc2c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D11 compound treatment 51440.0 -3000.0 -0.17 39840.0 -4390.0 -0.33 -0.3576 -0.9542 1281983 TimTec1_006413 COc1cc(N)ccc1NC(=O)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D12 compound treatment 26920.0 -27500.0 -1.59 23240.0 -21000.0 -1.59 -2.2506 -1.0 3211232 TimTec1_006414 Brc1ccc(cc1)c2cc3-c4ccccc4CCn3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D13 compound treatment 35320.0 -19100.0 -1.11 28720.0 -15500.0 -1.17 -1.6132 -0.9996 1235800 TimTec1_006415 N(c1ccccc1)c2nc(nc3ccccc23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D14 compound treatment 56480.0 2040.0 0.12 44960.0 733.0 0.06 0.1229 0.9402 1261113 TimTec1_006416 OC(=O)C1CCCCC1C(=O)N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D15 compound treatment 14880.0 -39600.0 -2.29 19960.0 -24300.0 -1.84 -2.9194 -0.994 1120499 TimTec1_006417 O=C(CCN1Cc2ccccc2C1)c3ccc4OCCOc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D16 compound treatment 26760.0 -27700.0 -1.6 24400.0 -19800.0 -1.5 -2.1951 -0.9995 3211233 TimTec1_006418 Cc1ccc(NC2=CC(=O)CC(C2)c3ccc(Cl)cc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D17 compound treatment 50080.0 -4360.0 -0.25 37720.0 -6510.0 -0.49 -0.5268 -0.9518 1314383 TimTec1_006419 O=C(COc1ccc2ccccc2c1)N3CCNCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D18 compound treatment 54840.0 404.0 0.02 37960.0 -6270.0 -0.47 -0.3189 -0.6714 3211234 TimTec1_006420 CC(=O)N/C(=C/c1ccccc1)/C(=O)Nc2ccc(C)c(C)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D19 compound treatment 48960.0 -5480.0 -0.32 37160.0 -7070.0 -0.53 -0.6026 -0.9689 1461637 TimTec1_006421 CCC1C(NC(CC1(O)CC=C)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D20 compound treatment 17760.0 -36700.0 -2.12 15600.0 -28600.0 -2.17 -3.0348 -1.0 1679474 TimTec1_006422 CC1=C(CC(=C(C)N1)C(=O)c2ccccc2)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D21 compound treatment 45440.0 -9000.0 -0.52 32320.0 -11900.0 -0.9 -1.0059 -0.9661 1577332 TimTec1_006423 CC1(C)Cc2nc(N3CCCC3)c(C#N)cc2CO1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D22 compound treatment 47840.0 -6600.0 -0.38 40920.0 -3310.0 -0.25 -0.4473 -0.979 3088079 TimTec1_006424 CN(C)C(=O)CCSc1ccc(Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D23 mock treatment 57800.0 3360.0 0.19 43840.0 -388.0 -0.03 0.1171 0.594 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 D24 mock treatment 58680.0 4240.0 0.25 44160.0 -67.5 -0.01 0.1702 0.6923 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E01 compound treatment 54360.0 -76.3 0.0 44480.0 253.0 0.02 0.0104 0.5297 3211235 TimTec1_006425 Cc1nc(C)c(C(=O)O)c(c2ccc(F)cc2)c1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E02 compound treatment 5360.0 -49100.0 -2.84 5280.0 -38900.0 -2.95 -4.0952 -0.9998 3088081 TimTec1_006426 CCOc1nc(C)nc2n(C)c(=S)sc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E03 compound treatment 54000.0 -436.0 -0.03 50400.0 6170.0 0.47 0.3125 0.6679 3088082 TimTec1_006427 CC(C)(C)C(N)Cn1ccnc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E04 compound treatment 57720.0 3280.0 0.19 51600.0 7370.0 0.56 0.5291 0.8975 3211236 TimTec1_006428 NC(=O)c1cc2ccccc2nc1C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E05 compound treatment 27080.0 -27400.0 -1.58 23640.0 -20600.0 -1.56 -2.2227 -1.0 1461983 TimTec1_006429 CC(C)NC(=S)N1CCC(Cc2ccccc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E06 compound treatment 16520.0 -37900.0 -2.2 18440.0 -25800.0 -1.95 -2.9336 -0.9983 3211237 TimTec1_006430 CC12CCC3C(CC=C4CC(O)CCC34C)C2C/C(=C\c5ccc(cc5)C(F)(F)F)/C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E07 compound treatment 39600.0 -14800.0 -0.86 34880.0 -9350.0 -0.71 -1.1081 -0.9953 3088086 TimTec1_006431 CCOC(=O)Cn1nnc(n1)c2ccc(OCc3ccccc3F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E08 compound treatment 42600.0 -11800.0 -0.69 37000.0 -7230.0 -0.55 -0.8718 -0.9937 3088087 TimTec1_006432 CC(=O)Oc1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E09 compound treatment 51480.0 -2960.0 -0.17 40840.0 -3390.0 -0.26 -0.3024 -0.9808 3211238 TimTec1_006433 COC(=O)/N=c/1\[cH-][n+](no1)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E10 compound treatment 55640.0 1200.0 0.07 51040.0 6810.0 0.52 0.4139 0.7955 3088089 TimTec1_006434 N#Cc1c(SCc2nc3ccccc3[nH]2)nc(cc1c4ccco4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E11 compound treatment 48960.0 -5480.0 -0.32 38360.0 -5870.0 -0.44 -0.5384 -0.9864 1643293 TimTec1_006435 S=C(Nc1cccnc1)N2CCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E12 compound treatment 32360.0 -22100.0 -1.28 27080.0 -17100.0 -1.3 -1.8222 -1.0 3211239 TimTec1_006436 CCS(=O)(=O)c1nnnn1c2ccccc2S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E13 compound treatment 50320.0 -4120.0 -0.24 44680.0 453.0 0.03 -0.1444 -0.5994 3088092 TimTec1_006437 CC1Cc2scc[n+]2-c3ccccc3N1C=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E14 compound treatment 34040.0 -20400.0 -1.18 29360.0 -14900.0 -1.13 -1.6314 -0.9997 3211240 TimTec1_006438 Cc1c(c2ccc(Br)cc2)c(=O)oc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E15 compound treatment 50600.0 -3840.0 -0.22 36040.0 -8190.0 -0.62 -0.5954 -0.9043 1314711 TimTec1_006439 Oc1cccc(NC(=S)Nc2cccnc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E16 compound treatment 44960.0 -9480.0 -0.55 35160.0 -9070.0 -0.69 -0.8736 -0.9939 3088158 TimTec1_006440 CCC(=O)c1cc(N)ccc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E17 compound treatment 48760.0 -5680.0 -0.33 31760.0 -12500.0 -0.94 -0.8999 -0.9004 3088160 TimTec1_006441 COC(=O)C(NS(=O)(=O)c1ccc(cc1)N2CCCC2=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E18 compound treatment 54480.0 43.8 0.0 39480.0 -4750.0 -0.36 -0.2523 -0.7021 1280834 TimTec1_006442 O=C(c1ccc2[nH]c(=O)oc2c1)c3ccc4[nH]c(=O)oc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E19 compound treatment 44480.0 -9960.0 -0.58 32960.0 -11300.0 -0.85 -1.011 -0.9819 3088162 TimTec1_006443 Cc1cn(CCOc2ccc(Cl)cc2)c(=O)[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E20 compound treatment 15720.0 -38700.0 -2.24 13440.0 -30800.0 -2.33 -3.234 -0.9998 1786935 TimTec1_006444 COc1ccc2nc(C)cc(SCC(=O)c3ccc(Cl)cc3)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E21 compound treatment 44200.0 -10200.0 -0.59 35360.0 -8870.0 -0.67 -0.894 -0.9981 3088165 TimTec1_006445 CCn1c2sc(C)nc2c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E22 compound treatment 43560.0 -10900.0 -0.63 38360.0 -5870.0 -0.44 -0.7596 -0.9853 1187778 TimTec1_006446 CCc1ccccc1NC(=O)Cc2ccc(Br)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E23 mock treatment 55120.0 684.0 0.04 52600.0 8370.0 0.63 0.4761 0.7498 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 E24 mock treatment 54320.0 -116.0 -0.01 45480.0 1250.0 0.09 0.0623 0.6552 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F01 compound treatment 50480.0 -3960.0 -0.23 42720.0 -1510.0 -0.11 -0.2428 -0.9481 1527015 TimTec1_006447 CC(C)Nc1nc(NC(C)C)nc(Nn2cnnc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F02 compound treatment 49120.0 -5320.0 -0.31 47640.0 3410.0 0.26 -0.0351 -0.0874 3088167 TimTec1_006448 OC(=O)c1ccccc1C(=O)NCCCn2ccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F03 compound treatment 33320.0 -21100.0 -1.22 31400.0 -12800.0 -0.97 -1.5517 -0.9934 1774253 TimTec1_006449 CC(=C)C1Cc2cc3ccc(=O)oc3cc2O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F04 compound treatment 14520.0 -39900.0 -2.31 20040.0 -24200.0 -1.83 -2.9299 -0.9933 1327284 TimTec1_006450 O=C(Nc1ccc(cc1)c2csc(n2)c3ccccc3)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F05 compound treatment 44440.0 -10000.0 -0.58 44280.0 52.5 0.0 -0.4067 -0.7022 3211241 TimTec1_006451 CCC(C)(C)C(=O)NC(c1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F06 compound treatment 46000.0 -8440.0 -0.49 40080.0 -4150.0 -0.31 -0.5676 -0.9771 1238234 TimTec1_006452 Cc1cc(C)n(n1)c2cc(Nc3ccc(C)cc3)nc(n2)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F07 compound treatment 52760.0 -1680.0 -0.1 40960.0 -3270.0 -0.25 -0.2436 -0.9166 1039376 TimTec1_006453 CCOC(=O)CNc1cccc(c1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F08 compound treatment 50920.0 -3520.0 -0.2 51800.0 7570.0 0.57 0.2613 0.4295 1251321 TimTec1_006454 Oc1c(C(=O)NCc2cccnc2)c(=O)n(CC=C)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F09 compound treatment 30400.0 -24000.0 -1.39 29480.0 -14700.0 -1.12 -1.7741 -0.994 3211242 TimTec1_006455 OC(CC#CCN1CCCC1)(C2CCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F10 compound treatment 23120.0 -31300.0 -1.81 19000.0 -25200.0 -1.91 -2.6332 -0.9997 1460065 TimTec1_006456 COc1ccc(OCc2nc3ccccc3n2CC(C)C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F11 compound treatment 41080.0 -13400.0 -0.77 34560.0 -9670.0 -0.73 -1.0646 -0.9996 1200425 TimTec1_006457 CC(=O)N1NC(CC1c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F12 compound treatment 42200.0 -12200.0 -0.71 31120.0 -13100.0 -0.99 -1.2029 -0.9864 1370319 TimTec1_006458 C=CCn1c(=O)c2c3CCCCc3sc2[nH]c1=S 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F13 compound treatment 39960.0 -14500.0 -0.84 31840.0 -12400.0 -0.94 -1.2561 -0.9985 3211243 TimTec1_006459 Cc1cc(Oc2ccccc2)nc(n1)c3ccc(Br)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F14 compound treatment 27520.0 -26900.0 -1.56 19480.0 -24700.0 -1.87 -2.4273 -0.9958 1175134 TimTec1_006460 Nc1nc(cs1)c2ccc(OCc3ccc(Br)cc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F15 compound treatment 49000.0 -5440.0 -0.31 41280.0 -2950.0 -0.22 -0.3805 -0.9857 3088175 TimTec1_006461 COc1ccc(cc1)[S+]2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F16 compound treatment 55600.0 1160.0 0.07 40360.0 -3870.0 -0.29 -0.1593 -0.5304 1456348 TimTec1_006462 O=C(N1CCOCC1)C2(CC3CC4C2)CC(C3)CC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F17 compound treatment 10320.0 -44100.0 -2.56 9880.0 -34300.0 -2.6 -3.6458 -1.0 1618640 TimTec1_006463 Cc1sc2ncnc(NCc3cccnc3)c2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F18 compound treatment 55840.0 1400.0 0.08 47440.0 3210.0 0.24 0.2295 0.8949 1467012 TimTec1_006464 COc1ccc(NC(=O)C2CCCCN2N)cc1OCC(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F19 compound treatment 49480.0 -4960.0 -0.29 40600.0 -3630.0 -0.27 -0.3972 -0.9997 1706198 TimTec1_006465 CCC(=O)N1C(CC2CC=C(C)C2(C)C)C3=C(CC(C)(C)CC3=O)Nc4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F20 compound treatment 43640.0 -10800.0 -0.63 38480.0 -5750.0 -0.44 -0.7499 -0.9843 1345040 TimTec1_006466 CCN(CC)c1ccc2cc(c3nnc(o3)c4cccnc4)c(=O)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F21 compound treatment 60200.0 5760.0 0.33 46320.0 2090.0 0.16 0.3481 0.9419 1688068 TimTec1_006467 NC(=O)c1ccccc1NC(=O)CCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F22 compound treatment 52840.0 -1600.0 -0.09 37920.0 -6310.0 -0.48 -0.403 -0.8287 3248073 TimTec1_006468 Cc1n[nH]c(C)c1[C@]2(C[C@H]3C[C@H]4C[C@H](C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F23 mock treatment 57640.0 3200.0 0.19 49240.0 5010.0 0.38 0.3995 0.9459 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 F24 mock treatment 62160.0 7720.0 0.45 48200.0 3970.0 0.3 0.5291 0.9813 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G01 compound treatment 1440.0 -53000.0 -3.07 1800.0 -42400.0 -3.21 -4.442 -0.9997 3211441 TimTec1_006469 CCn1c(=O)n(CC)c2cc(ccc12)S(=O)(=O)N3CCc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G02 compound treatment 46200.0 -8240.0 -0.48 43720.0 -508.0 -0.04 -0.3646 -0.7616 3088256 TimTec1_006470 Fc1ccc(OC(=O)c2nsc(Cl)c2Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G03 compound treatment 53440.0 -996.0 -0.06 43000.0 -1230.0 -0.09 -0.1065 -0.9738 3211442 TimTec1_006471 CC(C)(C)C(CN1CCCC1)OC(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G04 compound treatment 51760.0 -2680.0 -0.16 43400.0 -828.0 -0.06 -0.1539 -0.9205 3088258 TimTec1_006472 NC(=N)NC(=N)N1N=CCC1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G05 compound treatment 46000.0 -8440.0 -0.49 40200.0 -4030.0 -0.3 -0.5612 -0.9742 3211443 TimTec1_006473 Cc1ccc(cc1)C(=O)OCC2OC3OC(C)(C)OC3C2O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G06 compound treatment 39000.0 -15400.0 -0.89 33240.0 -11000.0 -0.83 -1.2205 -0.9993 3211444 TimTec1_006474 NS(=O)(=O)c1ccc(cc1)S(=O)(=O)NCC(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G07 compound treatment 40320.0 -14100.0 -0.82 34280.0 -9950.0 -0.75 -1.1107 -0.9991 1310353 TimTec1_006475 S=C(NC1CCCCCCC1)Nc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G08 compound treatment 49600.0 -4840.0 -0.28 41120.0 -3110.0 -0.24 -0.3645 -0.9962 3088261 TimTec1_006476 CC(=O)Oc1ccc(C)cc1C(O)(C(F)(F)F)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G09 compound treatment 49320.0 -5120.0 -0.3 40520.0 -3710.0 -0.28 -0.408 -0.9996 3211445 TimTec1_006477 CSC1=NC(C)(C)CC2(CC(c3cccs3)c4ccc(O)c(O)c4O2)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G10 compound treatment 44680.0 -9760.0 -0.57 40320.0 -3910.0 -0.3 -0.6088 -0.9544 3088263 TimTec1_006478 Cc1cc(=O)[nH]c2n(nc(O)c12)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G11 compound treatment 47160.0 -7280.0 -0.42 32280.0 -11900.0 -0.9 -0.9376 -0.9396 3211446 TimTec1_006479 CCCN(CC1CC1)C(=S)Nc2cccc(C)c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G12 compound treatment 51880.0 -2560.0 -0.15 38840.0 -5390.0 -0.41 -0.3931 -0.906 3088265 TimTec1_006480 OC(=O)c1cc(=O)c2cc(Br)ccc2o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G13 compound treatment 13920.0 -40500.0 -2.35 12040.0 -32200.0 -2.44 -3.3827 -0.9998 3211447 TimTec1_006481 CCOc1cc2CNC(c3cccn3-c2cc1OCC)c4c(O)cccc4OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G14 compound treatment 46160.0 -8280.0 -0.48 38160.0 -6070.0 -0.46 -0.6638 -0.9998 1098644 TimTec1_006482 C=CCOc1ccc2ccc(=O)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G15 compound treatment 26640.0 -27800.0 -1.61 26600.0 -17600.0 -1.33 -2.0823 -0.9956 3211448 TimTec1_006483 O=C(Cc1ccccc1)N2CCN(CC2)c3nc4ccccc4o3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G16 compound treatment 39640.0 -14800.0 -0.86 29800.0 -14400.0 -1.09 -1.3784 -0.9928 1202156 TimTec1_006484 CCC(C)n1ncn(c2ccc(cc2)N3CCN(CC3)c4ccc(OC)cc4)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G17 compound treatment 46720.0 -7720.0 -0.45 37920.0 -6310.0 -0.48 -0.6537 -0.9995 3088269 TimTec1_006485 CC1CCc2c(C1)sc3nc(SCc4nc(no4)c5ccccc5)n(C)c(=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G18 compound treatment 57200.0 2760.0 0.16 37720.0 -6510.0 -0.49 -0.2351 -0.4539 3211449 TimTec1_006486 COC(=O)C1=C(O)c2ccccc2S(=O)(=O)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G19 compound treatment 46760.0 -7680.0 -0.44 42280.0 -1950.0 -0.15 -0.4187 -0.8937 3211450 TimTec1_006487 CCNc1nc(NCC)n2c(SCC(=O)c3cccs3)nnc2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G20 compound treatment 49360.0 -5080.0 -0.29 38000.0 -6230.0 -0.47 -0.5413 -0.9742 3088271 TimTec1_006488 Cc1ccc(SCC(=O)Nc2ccc(C)cc2C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G21 compound treatment 46840.0 -7600.0 -0.44 41320.0 -2910.0 -0.22 -0.4668 -0.9487 3211451 TimTec1_006489 Fc1ccc(NC2=CC(CC2=O)N3CCCCC3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G22 compound treatment 54000.0 -436.0 -0.03 42360.0 -1870.0 -0.14 -0.1178 -0.8205 1498860 TimTec1_006490 C(C1Cc2ccccc2O1)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G23 mock treatment 55800.0 1360.0 0.08 43840.0 -388.0 -0.03 0.0351 0.4168 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 G24 mock treatment 56400.0 1960.0 0.11 45080.0 853.0 0.06 0.1261 0.9639 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H01 compound treatment 42880.0 -11600.0 -0.67 36000.0 -8230.0 -0.62 -0.9138 -0.9993 1353778 TimTec1_006491 CCOC(=O)CC1(CCOC(C)(C)C1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H02 compound treatment 55160.0 724.0 0.04 48280.0 4050.0 0.31 0.2466 0.7964 1342963 TimTec1_006492 CN1CCC2(CCN(Cc3ccccc3)C2)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H03 compound treatment 38760.0 -15700.0 -0.91 34760.0 -9470.0 -0.72 -1.149 -0.9931 3211452 TimTec1_006493 Cc1cc(nc(c1C)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H04 compound treatment 36000.0 -18400.0 -1.07 32720.0 -11500.0 -0.87 -1.3712 -0.9949 1735148 TimTec1_006494 Cc1cccc(Nc2cc(C)nc3ccccc23)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H05 compound treatment 39000.0 -15400.0 -0.89 31280.0 -12900.0 -0.98 -1.3254 -0.999 3088347 TimTec1_006495 CCOC(=O)c1c(C)n(C)c2ccc(OCC)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H06 compound treatment 25200.0 -29200.0 -1.69 20120.0 -24100.0 -1.82 -2.4881 -0.9993 3211453 TimTec1_006496 FC(F)(F)C1CC(Nc2c(cnn12)C(=O)Nc3cccc4ccccc34)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H07 compound treatment 30600.0 -23800.0 -1.38 28920.0 -15300.0 -1.16 -1.7958 -0.9962 1313366 TimTec1_006497 CCOc1ccc(CNC2CCCc3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H08 compound treatment 30840.0 -23600.0 -1.37 27560.0 -16700.0 -1.26 -1.8588 -0.9992 3211454 TimTec1_006498 NC1=C(C#N)C(C(=C(N)S1)C#N)c2ccccc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H09 compound treatment 40680.0 -13800.0 -0.8 34960.0 -9270.0 -0.7 -1.0596 -0.998 1379894 TimTec1_006499 CC(=O)Nc1cccc(c1)c2nc3ccccc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H10 compound treatment 19000.0 -35400.0 -2.05 13040.0 -31200.0 -2.36 -3.121 -0.9976 3088351 TimTec1_006500 COc1ccc(cc1)c2c(C)oc3ccc(C)cc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H11 compound treatment 34400.0 -20000.0 -1.16 31640.0 -12600.0 -0.95 -1.4946 -0.9952 1710850 TimTec1_006501 CCCc1cc(O)c2c(C)cc(=O)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H12 compound treatment 1560.0 -52900.0 -3.06 1240.0 -43000.0 -3.25 -4.4671 -0.9995 3211455 TimTec1_006502 Cc1ccc(cc1)C(=O)NCCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H13 compound treatment 67440.0 13000.0 0.75 51360.0 7130.0 0.54 0.9145 0.9866 1733570 TimTec1_006503 Cc1ccc(Nc2nnc(c3ccccc3)c4ccccc24)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H14 compound treatment 48400.0 -6040.0 -0.35 42040.0 -2190.0 -0.17 -0.3644 -0.9417 1118121 TimTec1_006504 CC1(C)CC(=C(CC2C(=O)CC(C)(C)CC2=O)C(=O)C1)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H15 compound treatment 50920.0 -3520.0 -0.2 41920.0 -2310.0 -0.17 -0.2676 -0.9971 1591866 TimTec1_006505 O=S1(=O)CCC(C1)NC2CCS(=O)(=O)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H16 compound treatment 38640.0 -15800.0 -0.92 35400.0 -8830.0 -0.67 -1.1196 -0.988 3088354 TimTec1_006506 CC(C)(C)S(=O)(=O)c1ccc2ccccc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H17 compound treatment 34040.0 -20400.0 -1.18 25960.0 -18300.0 -1.38 -1.8133 -0.9969 1442109 TimTec1_006507 CCC1C(=C(NC2=C1C(=O)CC(C)(C)C2)SC)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H18 compound treatment 56040.0 1600.0 0.09 45520.0 1290.0 0.1 0.1349 0.9997 1161095 TimTec1_006508 COc1cccc(CNC2CCCC2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H19 compound treatment 49440.0 -5000.0 -0.29 39200.0 -5030.0 -0.38 -0.4738 -0.9909 1180009 TimTec1_006509 Brc1ccc(o1)C(=O)Nc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H20 compound treatment 49960.0 -4480.0 -0.26 43040.0 -1190.0 -0.09 -0.2469 -0.8997 1788667 TimTec1_006510 COCC(C)NC(=O)c1c(C)onc1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H21 compound treatment 48240.0 -6200.0 -0.36 44000.0 -228.0 -0.02 -0.266 -0.7402 1569691 TimTec1_006511 CC(C)CC(=O)NCc1ccc2OCOc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H22 compound treatment 30120.0 -24300.0 -1.41 30320.0 -13900.0 -1.05 -1.7406 -0.9897 1573756 TimTec1_006512 OCCNc1nc2-c3ccccc3CC4(CCCCC4)c2c(=O)n1Cc5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H23 mock treatment 55120.0 684.0 0.04 45520.0 1290.0 0.1 0.0972 0.9208 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 H24 mock treatment 46840.0 -7600.0 -0.44 48240.0 4010.0 0.3 -0.0964 -0.1803 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I01 compound treatment 39040.0 -15400.0 -0.89 34960.0 -9270.0 -0.7 -1.1268 -0.9929 3211456 TimTec1_006513 NC(=O)C(Cc1ccccc1)NC(=O)c2ccccc2Sc3ccccc3C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I02 compound treatment 39120.0 -15300.0 -0.89 34800.0 -9430.0 -0.71 -1.1321 -0.9942 3088358 TimTec1_006514 N#Cc1ccc(CSc2nnc(c3cccs3)n2c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I03 compound treatment 44720.0 -9720.0 -0.56 38320.0 -5910.0 -0.45 -0.7142 -0.9935 3088360 TimTec1_006515 CCN(Cc1ccccc1)C(=O)CSc2nc(C)cc3COC(=O)c32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I04 compound treatment 49920.0 -4520.0 -0.26 43520.0 -708.0 -0.05 -0.2229 -0.8345 3211457 TimTec1_006516 CC1(C)OCC(O1)C2OC(=O)C3OC(C)(C)OC23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I05 compound treatment 23000.0 -31400.0 -1.82 24600.0 -19600.0 -1.49 -2.3384 -0.9949 3211458 TimTec1_006517 Cc1ccc2ncc(cc2c1)c3ccc4c(N)c(C)ccc4n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I06 compound treatment 1080.0 -53400.0 -3.09 1320.0 -42900.0 -3.25 -4.4825 -0.9997 3088362 TimTec1_006518 CN1C(=O)N(C)C(=O)C(C2CCC3OCC2O3)(C4CCC5OCC4O5)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I07 compound treatment 17000.0 -37400.0 -2.17 18040.0 -26200.0 -1.98 -2.9354 -0.999 3211459 TimTec1_006519 COc1ccc(cc1)C2N(C(=O)C32CCCC3)c4ccc(OC)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I08 compound treatment 53240.0 -1200.0 -0.07 48760.0 4530.0 0.34 0.1936 0.5531 3088364 TimTec1_006520 CCOC(=O)C1CNC(=S)NC1(C)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I09 compound treatment 4440.0 -50000.0 -2.9 4440.0 -39800.0 -3.01 -4.1778 -0.9998 3211538 TimTec1_006521 CC1(C)CC2(CC(c3ccccc3F)c4cc(Cl)c(O)cc4O2)NC(=S)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I10 compound treatment 400.0 -54000.0 -3.13 1080.0 -43100.0 -3.27 -4.5232 -0.9998 3211539 TimTec1_006522 CC1(C)Cc2c(CS1)c(nc3sc4c(Cl)nnnc4c23)N5CCOCC5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I11 compound treatment 53120.0 -1320.0 -0.08 42200.0 -2030.0 -0.15 -0.1624 -0.9479 3088367 TimTec1_006523 CCNCC1Cc2ccccc2O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I12 compound treatment 28880.0 -25600.0 -1.48 19240.0 -25000.0 -1.89 -2.3844 -0.9927 3088369 TimTec1_006524 Cc1ccc2oc(cc(=O)c2c1)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I13 compound treatment 34640.0 -19800.0 -1.15 25400.0 -18800.0 -1.43 -1.8187 -0.9942 3211540 TimTec1_006525 CN(C)c1nc(nc2n(c3ccccc3)c(=S)sc12)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I14 compound treatment 47920.0 -6520.0 -0.38 41040.0 -3190.0 -0.24 -0.4376 -0.9766 3088443 TimTec1_006526 CCOc1cc(=O)oc2ccc(Cl)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I15 compound treatment 42920.0 -11500.0 -0.67 33160.0 -11100.0 -0.84 -1.0642 -0.9936 1518517 TimTec1_006527 CCCN(CC1CC1)C(=S)Nc2ccc(OCC)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I16 compound treatment 51200.0 -3240.0 -0.19 36000.0 -8230.0 -0.62 -0.573 -0.8809 3211541 TimTec1_006528 COc1ccc(cc1Br)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I17 compound treatment 53600.0 -836.0 -0.05 39640.0 -4590.0 -0.35 -0.2798 -0.798 3211542 TimTec1_006529 OC(=O)CC(N1C(=O)CCC1=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I18 compound treatment 48480.0 -5960.0 -0.35 42520.0 -1710.0 -0.13 -0.3354 -0.9102 3088447 TimTec1_006530 COC(=O)C1=C(O)c2ccccc2S(=O)(=O)N1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I19 compound treatment 33200.0 -21200.0 -1.23 25280.0 -18900.0 -1.43 -1.8842 -0.9971 1478025 TimTec1_006531 COc1ccc2CN(C(=O)c2c1OC)c3ccc(F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I20 compound treatment 54000.0 -436.0 -0.03 44520.0 293.0 0.02 -0.0022 -0.066 3088449 TimTec1_006532 CNC(=O)CSc1ccc(Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I21 compound treatment 47560.0 -6880.0 -0.4 39640.0 -4590.0 -0.35 -0.5272 -0.9977 1596437 TimTec1_006533 S=C(NCCN1CCOCC1)Nc2ccc(C#N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I22 compound treatment 54480.0 43.8 0.0 41960.0 -2270.0 -0.17 -0.1196 -0.6966 1592947 TimTec1_006534 OC(=O)c1oc2ccccc2c1CSc3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I23 mock treatment 55840.0 1400.0 0.08 45440.0 1210.0 0.09 0.1224 0.9982 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 I24 mock treatment 54400.0 -36.3 0.0 42680.0 -1550.0 -0.12 -0.0843 -0.7197 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J01 compound treatment 42600.0 -11800.0 -0.69 44640.0 413.0 0.03 -0.4628 -0.6742 1534128 TimTec1_006535 CCCCC1CCC(CC1)C(=O)OCC(=O)c2ccc(Br)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J02 compound treatment 35720.0 -18700.0 -1.08 33240.0 -11000.0 -0.83 -1.3549 -0.9914 1169194 TimTec1_006536 O=C(CSc1nsc(SCC(=O)N2CCCCC2)c1C#N)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J03 compound treatment 50680.0 -3760.0 -0.22 45440.0 1210.0 0.09 -0.089 -0.3768 1496370 TimTec1_006537 COc1ccc(OCC(=O)NCC(=O)O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J04 compound treatment 30200.0 -24200.0 -1.4 31080.0 -13100.0 -1.0 -1.6966 -0.9858 1291245 TimTec1_006538 CCOc1ccc2NC(C3CC=CC3c2c1)c4ccc(cc4)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J05 compound treatment 45880.0 -8560.0 -0.5 42960.0 -1270.0 -0.1 -0.4184 -0.8286 3088453 TimTec1_006539 OC(=O)C1C(C2OC1C=C2)C(=O)Nc3cccc(c3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J06 compound treatment 3960.0 -50500.0 -2.92 6560.0 -37700.0 -2.85 -4.084 -0.9999 1271879 TimTec1_006540 O=C(Cc1cccs1)Nc2nc(cs2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J07 compound treatment 51920.0 -2520.0 -0.15 42200.0 -2030.0 -0.15 -0.2116 -0.9997 1072955 TimTec1_006541 COc1ccc(cc1)c2cc([nH]n2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J08 compound treatment 43360.0 -11100.0 -0.64 31320.0 -12900.0 -0.98 -1.1446 -0.9792 3211543 TimTec1_006542 COc1cccc(c1)C2CC(n3ncc(C(=O)N4CCCCC4C)c3N2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J09 compound treatment 30880.0 -23600.0 -1.36 21600.0 -22600.0 -1.71 -2.1762 -0.9937 1695584 TimTec1_006543 CC(=CCC(C)(C)C1OCCN1C(=O)c2ccccc2)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J10 compound treatment 15760.0 -38700.0 -2.24 9240.0 -35000.0 -2.65 -3.4572 -0.9965 1201910 TimTec1_006544 Cc1cccc2c(C)cc(SCCC(=O)O)nc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J11 compound treatment 40560.0 -13900.0 -0.8 32280.0 -11900.0 -0.9 -1.208 -0.9983 1651502 TimTec1_006545 CC(C(=O)Nc1ccccc1)C(=O)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J12 compound treatment 43920.0 -10500.0 -0.61 36680.0 -7550.0 -0.57 -0.8348 -0.9995 1498972 TimTec1_006546 OC(=O)CCCC(=O)Nc1ccc(Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J13 compound treatment 40520.0 -13900.0 -0.81 30480.0 -13700.0 -1.04 -1.3059 -0.992 1609094 TimTec1_006547 C(Nc1ccccn1)C2COc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J14 compound treatment 39080.0 -15400.0 -0.89 35040.0 -9190.0 -0.7 -1.1209 -0.9926 1441843 TimTec1_006548 CCOC(=O)CC(=O)c1c[nH]c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J15 compound treatment 41600.0 -12800.0 -0.74 33480.0 -10700.0 -0.81 -1.1011 -0.999 1692597 TimTec1_006549 COc1ccc(cc1)c2cc(C)nc(N)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J16 compound treatment 37000.0 -17400.0 -1.01 26920.0 -17300.0 -1.31 -1.6407 -0.9918 1475363 TimTec1_006550 OC1(CC(=O)c2ccc(Cl)cc2)OC(=CC1=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J17 compound treatment 28080.0 -26400.0 -1.53 12160.0 -32100.0 -2.43 -2.7961 -0.975 3088459 TimTec1_006551 CC1=CC(C)(C)N=C(Nc2nc(C)c3cc(C)cc(C)c3n2)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J18 compound treatment 52520.0 -1920.0 -0.11 39800.0 -4430.0 -0.34 -0.3155 -0.8936 1438712 TimTec1_006552 CC(C)CC(=O)N1CCN(Cc2cccc(C)c2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J19 compound treatment 3240.0 -51200.0 -2.97 1960.0 -42300.0 -3.2 -4.3597 -0.9993 1215237 TimTec1_006553 O=C(Nc1ccccn1)c2cc3ccccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J20 compound treatment 48200.0 -6240.0 -0.36 31200.0 -13000.0 -0.99 -0.9528 -0.9072 1739248 TimTec1_006554 CC(C)CN(CC(C)C)Cc1c(O)ccc2c(=O)c(coc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J21 compound treatment 38680.0 -15800.0 -0.91 30440.0 -13800.0 -1.04 -1.3835 -0.9978 3088529 TimTec1_006555 Cc1ccc(C)c(Cc2cc(Cl)ccc2Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J22 compound treatment 41240.0 -13200.0 -0.76 38960.0 -5270.0 -0.4 -0.8226 -0.9539 1779992 TimTec1_006556 COc1ccc2oc(/C=C/N(C)C)c(C(=O)c3ccc(Br)cc3)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J23 mock treatment 48920.0 -5520.0 -0.32 44200.0 -27.5 0.0 -0.2275 -0.7117 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 J24 mock treatment 45600.0 -8840.0 -0.51 39040.0 -5190.0 -0.39 -0.6397 -0.9914 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K01 compound treatment 35000.0 -19400.0 -1.13 25640.0 -18600.0 -1.41 -1.7911 -0.9939 3088531 TimTec1_006557 CC(=O)Nc1cc(ccc1N2CCN(CC2)c3ccccc3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K02 compound treatment 41080.0 -13400.0 -0.77 33280.0 -10900.0 -0.83 -1.1331 -0.9994 3211545 TimTec1_006558 COc1cc(OC)nc(NC(=O)C(C)C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K03 compound treatment 27040.0 -27400.0 -1.59 25440.0 -18800.0 -1.42 -2.128 -0.9985 3088533 TimTec1_006559 Cc1cc2COC(=O)c2c(SCc3ccc(Cl)cc3)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K04 compound treatment 1480.0 -53000.0 -3.07 1240.0 -43000.0 -3.25 -4.4704 -0.9996 3211546 TimTec1_006560 COc1ccc(cc1)c2nc(no2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K05 compound treatment 34160.0 -20300.0 -1.17 27040.0 -17200.0 -1.3 -1.7506 -0.9987 1870743 TimTec1_006561 COc1cc(ccc1OC(C)C)C2NCCc3c2[nH]c4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K06 compound treatment 43120.0 -11300.0 -0.66 37080.0 -7150.0 -0.54 -0.8462 -0.9954 3088535 TimTec1_006562 N#CC(=C1NN=NN1c2ccccc2)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K07 compound treatment 42320.0 -12100.0 -0.7 32600.0 -11600.0 -0.88 -1.1187 -0.9937 3088537 TimTec1_006563 CC1(C)C(OC(=O)C(C)(C)C1=O)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K08 compound treatment 38840.0 -15600.0 -0.9 31320.0 -12900.0 -0.98 -1.3298 -0.9992 3211547 TimTec1_006564 Cc1ccccc1COc2ccc(cc2)c3nnn[nH]3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K09 compound treatment 22840.0 -31600.0 -1.83 18320.0 -25900.0 -1.96 -2.6811 -0.9994 3211548 TimTec1_006565 CC1(C)NC(=S)NC(=C1)/C=C/c2ccccc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K10 compound treatment 44280.0 -10200.0 -0.59 34120.0 -10100.0 -0.77 -0.9571 -0.9916 3088539 TimTec1_006566 CCC1(C)Cc2c(C#N)c(N)n(c3ccccc3)c(=O)c2CO1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K11 compound treatment 720.0 -53700.0 -3.11 640.0 -43600.0 -3.3 -4.5336 -0.9996 3211549 TimTec1_006567 CC1(C)Cc2c(ccc3ccccc23)C(=N1)Sc4ccc(N)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K12 compound treatment 25320.0 -29100.0 -1.69 19960.0 -24300.0 -1.84 -2.4917 -0.9991 3088542 TimTec1_006568 Oc1ccc2c(c3ccccc3)c(c4ccccc4)c(=O)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K13 compound treatment 6080.0 -48400.0 -2.8 9760.0 -34500.0 -2.61 -3.8259 -0.9994 3211550 TimTec1_006569 Cc1ccc(c(C)c1)n2nnnc2S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K14 compound treatment 17800.0 -36600.0 -2.12 13520.0 -30700.0 -2.32 -3.1445 -0.999 3088543 TimTec1_006570 Cc1cccc(c1)c2cc(=O)c3cc(C)ccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K15 compound treatment 37600.0 -16800.0 -0.98 28960.0 -15300.0 -1.16 -1.5069 -0.9964 1568310 TimTec1_006571 CSc1ccccc1NC(=S)Nc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K16 compound treatment 21520.0 -32900.0 -1.91 19840.0 -24400.0 -1.85 -2.6538 -0.9999 3211551 TimTec1_006572 COc1cc(OC)c2c(=O)c(coc2c1)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K17 compound treatment 39400.0 -15000.0 -0.87 27880.0 -16300.0 -1.24 -1.491 -0.9852 3088546 TimTec1_006573 Cc1cn2c(nc(=S)nc2s1)c3ccccc3F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K18 compound treatment 18680.0 -35800.0 -2.07 13520.0 -30700.0 -2.32 -3.1085 -0.9984 3088547 TimTec1_006574 Oc1cccc(c1)C2CC(=O)c3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K19 compound treatment 22840.0 -31600.0 -1.83 17200.0 -27000.0 -2.05 -2.7411 -0.9985 3211552 TimTec1_006575 CCOC(=O)C1C2c3ccccc3O[C@]1(C)N=c4s/c(=C/c5ccc(OC)cc5)/c(=O)n24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K20 compound treatment 40120.0 -14300.0 -0.83 29920.0 -14300.0 -1.08 -1.3523 -0.9913 1160836 TimTec1_006576 COC(=O)C1C(C(C1c2ccccc2)C(=O)OCc3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K21 compound treatment 38160.0 -16300.0 -0.94 32040.0 -12200.0 -0.92 -1.3191 -0.9999 1239220 TimTec1_006577 COc1ccccc1NC(=S)N2CCCCC2CO 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K22 compound treatment 34320.0 -20100.0 -1.17 24720.0 -19500.0 -1.48 -1.8682 -0.9931 3211553 TimTec1_006578 C1CCc2c(C1)n(c3ccccc3)c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K23 mock treatment 43760.0 -10700.0 -0.62 34800.0 -9430.0 -0.71 -0.942 -0.9975 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 K24 mock treatment 38320.0 -16100.0 -0.93 34960.0 -9270.0 -0.7 -1.1563 -0.9901 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L01 compound treatment 49040.0 -5400.0 -0.31 40480.0 -3750.0 -0.28 -0.4217 -0.9988 3088551 TimTec1_006579 CCn1c(=O)oc2cc(Br)ccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L02 compound treatment 44720.0 -9720.0 -0.56 40040.0 -4190.0 -0.32 -0.6222 -0.9631 1255982 TimTec1_006580 COc1cc(OC)c(cc1OC)C(=O)CCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L03 compound treatment 44400.0 -10000.0 -0.58 41800.0 -2430.0 -0.18 -0.5411 -0.8873 1156741 TimTec1_006581 CCC(C)NC(=O)c1ccccc1c2ccccc2C(=O)NC(C)CC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L04 compound treatment 53320.0 -1120.0 -0.06 36400.0 -7830.0 -0.59 -0.4647 -0.7797 1735137 TimTec1_006582 CC1CN(CC(C)O1)C(=O)c2ccc(N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L05 compound treatment 40600.0 -13800.0 -0.8 31440.0 -12800.0 -0.97 -1.2513 -0.9956 3087493 TimTec1_006583 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3ccc4ccccc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L06 compound treatment 48800.0 -5640.0 -0.33 40240.0 -3990.0 -0.3 -0.4443 -0.9992 1637432 TimTec1_006584 CC1(CN(CC2(C)CN(C1)C(=O)c3ccccc3)C(=O)c4ccccc4)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L07 compound treatment 48120.0 -6320.0 -0.37 38680.0 -5550.0 -0.42 -0.5557 -0.9977 3087495 TimTec1_006585 Brc1ccc(cc1)c2noc(n2)c3ccc(Br)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L08 compound treatment 44640.0 -9800.0 -0.57 31680.0 -12500.0 -0.95 -1.0729 -0.9697 1144835 TimTec1_006586 CCc1c(C)nc2cc(nn2c1O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L09 compound treatment 50200.0 -4240.0 -0.25 31280.0 -12900.0 -0.98 -0.8666 -0.8577 3087497 TimTec1_006587 CC(=O)OCCCn1c(C)nc2cc(Cl)ccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L10 compound treatment 34480.0 -20000.0 -1.16 25400.0 -18800.0 -1.43 -1.8253 -0.9946 3211639 TimTec1_006588 CCCCC(=O)C1CCC(CC1)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L11 compound treatment 28760.0 -25700.0 -1.49 22680.0 -21500.0 -1.63 -2.2052 -0.9989 1423564 TimTec1_006589 COc1cccc(NC(=O)CSc2ccccc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L12 compound treatment 45800.0 -8640.0 -0.5 41240.0 -2990.0 -0.23 -0.5137 -0.9356 3211640 TimTec1_006590 COc1ccc(cc1)C2N(CCO)C(=O)C(=C2C(=O)/C=C/c3ccccc3)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L13 compound treatment 48280.0 -6160.0 -0.36 36960.0 -7270.0 -0.55 -0.6412 -0.978 1119356 TimTec1_006591 COc1ccc(Cl)cc1CN2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L14 compound treatment 37200.0 -17200.0 -1.0 27120.0 -17100.0 -1.29 -1.6218 -0.9918 1538287 TimTec1_006592 OCCn1c(cn2c1nc3ccccc32)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L15 compound treatment 8760.0 -45700.0 -2.65 5720.0 -38500.0 -2.91 -3.9323 -0.9988 3211641 TimTec1_006593 Nc1nc(cc(c1C#N)c2ccc3OCOc3c2)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L16 compound treatment 35240.0 -19200.0 -1.11 25960.0 -18300.0 -1.38 -1.7642 -0.9942 1511443 TimTec1_006594 CC(Cc1ccccc1)NC(=O)c2ccc(N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L17 compound treatment 39360.0 -15100.0 -0.87 27040.0 -17200.0 -1.3 -1.5376 -0.9812 1541381 TimTec1_006595 O=C(CCCN1C(=O)c2ccccc2C1=O)NC3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L18 compound treatment 49920.0 -4520.0 -0.26 35000.0 -9230.0 -0.7 -0.6789 -0.9102 3087502 TimTec1_006596 ON=C(C(=O)c1ccccc1)C(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L19 compound treatment 480.0 -54000.0 -3.13 320.0 -43900.0 -3.32 -4.5606 -0.9995 1710724 TimTec1_006597 O=C(CCCc1ccccc1)c2ccc3OCCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L20 compound treatment 49120.0 -5320.0 -0.31 43600.0 -628.0 -0.05 -0.2514 -0.8066 1446113 TimTec1_006598 CC(=O)Nc1ccc(Nc2nc(c3ccccc3)c4cc(Br)ccc4n2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L21 compound treatment 42720.0 -11700.0 -0.68 36360.0 -7870.0 -0.6 -0.9011 -0.9979 1019857 TimTec1_006599 O=C1N(C(C=C1Nc2ccccc2)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L22 compound treatment 46520.0 -7920.0 -0.46 33520.0 -10700.0 -0.81 -0.8974 -0.9637 1376758 TimTec1_006600 O=C(CCNc1ccccc1)n2c(=O)oc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L23 mock treatment 56520.0 2080.0 0.12 42000.0 -2230.0 -0.17 -0.0339 -0.1633 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 L24 mock treatment 51320.0 -3120.0 -0.18 39200.0 -5030.0 -0.38 -0.3968 -0.9419 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M01 compound treatment 55280.0 844.0 0.05 47640.0 3410.0 0.26 0.2172 0.8263 3087505 TimTec1_006601 COc1ccc(OCCNC(=O)C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M02 compound treatment 45920.0 -8520.0 -0.49 39920.0 -4310.0 -0.33 -0.5794 -0.9798 3211642 TimTec1_006602 O=C(CSc1nc2ccccc2o1)N3CCNC3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M03 compound treatment 48200.0 -6240.0 -0.36 39520.0 -4710.0 -0.36 -0.5075 -1.0 3211643 TimTec1_006603 CCNS(=O)(=O)c1ccc(OC)c2ncccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M04 compound treatment 48720.0 -5720.0 -0.33 37160.0 -7070.0 -0.53 -0.6125 -0.9734 3087508 TimTec1_006604 CCOC(=O)c1c(C)n(N2C(=O)CSC2=S)c(C)c1C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M05 compound treatment 42200.0 -12200.0 -0.71 32320.0 -11900.0 -0.9 -1.1386 -0.9929 1629022 TimTec1_006605 COc1ccc2cnn(c3ccccc3)c(=O)c2c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M06 compound treatment 48920.0 -5520.0 -0.32 32480.0 -11700.0 -0.89 -0.8548 -0.9046 3087510 TimTec1_006606 C1CCN(CC1)c2ccc(nn2)n3ccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M07 compound treatment 37280.0 -17200.0 -0.99 31840.0 -12400.0 -0.94 -1.3659 -0.9996 3211644 TimTec1_006607 CCC1(CC)C(OC(=O)C(C)(C)C1=O)c2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M08 compound treatment 43120.0 -11300.0 -0.66 28000.0 -16200.0 -1.23 -1.3322 -0.9568 3211645 TimTec1_006608 O=C1CC(Cc2nc(NCc3ccccc3)ncc12)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M09 compound treatment 18680.0 -35800.0 -2.07 16720.0 -27500.0 -2.08 -2.9372 -1.0 1747097 TimTec1_006609 CC(=O)Oc1ccc(c(OC(=O)C)c1)C2(CCCC23)Oc4cc(OC(=O)C)ccc4C53CCCC5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M10 compound treatment 27120.0 -27300.0 -1.58 24000.0 -20200.0 -1.53 -2.2018 -0.9999 3088015 TimTec1_006610 Fc1ccc(COc2ccccc2CNC3CCCC3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M11 compound treatment 41920.0 -12500.0 -0.73 37120.0 -7110.0 -0.54 -0.8932 -0.9892 3088017 TimTec1_006611 OC(=O)CC(c1ccccc1)n2cnnn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M12 compound treatment 34120.0 -20300.0 -1.18 22240.0 -22000.0 -1.66 -2.0092 -0.9856 1301285 TimTec1_006612 COc1ccc2oc(=O)c(cc2c1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M13 compound treatment 43240.0 -11200.0 -0.65 39120.0 -5110.0 -0.39 -0.7321 -0.9694 3211646 TimTec1_006613 CCOC(=O)COc1ccc(cc1)c2nnn[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M14 compound treatment 44880.0 -9560.0 -0.55 36600.0 -7630.0 -0.58 -0.7998 -0.9998 3088019 TimTec1_006614 COc1ccc2oc(=O)cc(O)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M15 compound treatment 43160.0 -11300.0 -0.65 35400.0 -8830.0 -0.67 -0.9344 -0.9999 1315478 TimTec1_006615 CCN(C(=S)Nc1cccnc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M16 compound treatment 36920.0 -17500.0 -1.01 27520.0 -16700.0 -1.26 -1.6119 -0.994 3088021 TimTec1_006616 COc1ccc2c(=O)c(coc2c1)c3ccc(OC)c(OC)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M17 compound treatment 36160.0 -18300.0 -1.06 27240.0 -17000.0 -1.29 -1.658 -0.9953 3211647 TimTec1_006617 CCCCS(=O)(=O)c1c(O)nc2ccc(Cl)cc2c1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M18 compound treatment 27720.0 -26700.0 -1.55 20840.0 -23400.0 -1.77 -2.3463 -0.9978 3088023 TimTec1_006618 COc1ccc(cc1)c2cc(=O)c3cccc(C)c3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M19 compound treatment 46360.0 -8080.0 -0.47 36800.0 -7430.0 -0.56 -0.7284 -0.9958 3211648 TimTec1_006619 CC1(C)CC(=O)C2=C(C1)Nc3cc4OCOc4cc3C2c5ccc(Cl)cc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M20 compound treatment 43440.0 -11000.0 -0.64 37440.0 -6790.0 -0.51 -0.8138 -0.9943 3088025 TimTec1_006620 CC(Sc1ccccc1)C(=O)Nc2ccc(CC#N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M21 compound treatment 44120.0 -10300.0 -0.6 37680.0 -6550.0 -0.5 -0.7731 -0.9957 1664070 TimTec1_006621 CCC(C)c1ccccc1NC(=S)Nc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M22 compound treatment 42920.0 -11500.0 -0.67 35760.0 -8470.0 -0.64 -0.925 -0.9998 1204548 TimTec1_006622 COc1cccc(c1)C(CC(=O)Nc2cccc3ccccc23)NC(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M23 mock treatment 50600.0 -3840.0 -0.22 39680.0 -4550.0 -0.34 -0.4006 -0.9776 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 M24 mock treatment 54200.0 -236.0 -0.01 39040.0 -5190.0 -0.39 -0.2873 -0.7313 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N01 compound treatment 30960.0 -23500.0 -1.36 26120.0 -18100.0 -1.37 -1.931 -1.0 3211649 TimTec1_006623 CCc1c(C)n[n+]2cnn(Cc3ccccc3)c2c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N02 compound treatment 31240.0 -23200.0 -1.34 25320.0 -18900.0 -1.43 -1.9623 -0.9995 1159257 TimTec1_006624 O=C(CC(c1ccccc1)c2ccccc2)NCC3COc4ccccc4O3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N03 compound treatment 38960.0 -15500.0 -0.9 29880.0 -14300.0 -1.09 -1.402 -0.9955 1523675 TimTec1_006625 CC(C)C1C(N(C)C(CC1(O)c2ccccc2)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N04 compound treatment 37040.0 -17400.0 -1.01 30800.0 -13400.0 -1.02 -1.4314 -1.0 1565133 TimTec1_006626 OC(=O)C1C(C(C1c2ccccc2)C(=O)N3CCOCC3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N05 compound treatment 17720.0 -36700.0 -2.13 14280.0 -29900.0 -2.27 -3.1071 -0.9995 3088098 TimTec1_006627 FC(F)(F)C(=O)Nc1cccc(c1)C(=O)OCC(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N06 compound treatment 6400.0 -48000.0 -2.78 4880.0 -39300.0 -2.98 -4.074 -0.9994 1325486 TimTec1_006628 O=C(Nc1cc2cc[nH]c2cn1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N07 compound treatment 23120.0 -31300.0 -1.81 19600.0 -24600.0 -1.86 -2.6011 -0.9999 1651914 TimTec1_006629 Cc1nc2c(Cl)cccc2c(O)c1CC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N08 compound treatment 1520.0 -52900.0 -3.07 1280.0 -42900.0 -3.25 -4.4666 -0.9996 1624701 TimTec1_006630 Nc1cc(nn1Cc2ccc(Cl)cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N09 compound treatment 34360.0 -20100.0 -1.16 27680.0 -16500.0 -1.25 -1.7082 -0.9993 3211650 TimTec1_006631 Cc1ccc(cc1)S(=O)(=O)C2CS(=O)(=O)CC2S(=O)(=O)c3ccc(C)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N10 compound treatment 42040.0 -12400.0 -0.72 26640.0 -17600.0 -1.33 -1.4492 -0.9581 1719238 TimTec1_006632 OC(=O)c1cnc2ccc(F)cc2c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N11 compound treatment 13000.0 -41400.0 -2.4 11320.0 -32900.0 -2.49 -3.4589 -0.9998 1420410 TimTec1_006633 O=C(Cc1ccccc1)NCC2(CCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N12 compound treatment 20040.0 -34400.0 -1.99 18960.0 -25300.0 -1.91 -2.7616 -0.9998 3211651 TimTec1_006634 CCN(CC)C(=O)COc1cc(C)c(Cl)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N13 compound treatment 16640.0 -37800.0 -2.19 12520.0 -31700.0 -2.4 -3.2456 -0.999 1106512 TimTec1_006635 Nc1nc(nc2sc3CCCCc3c12)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N14 compound treatment 24160.0 -30300.0 -1.75 17400.0 -26800.0 -2.03 -2.6763 -0.9973 3211652 TimTec1_006636 Cc1ccc(Sc2c(nc3ncccn23)c4ccccc4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N15 compound treatment 30200.0 -24200.0 -1.4 28640.0 -15600.0 -1.18 -1.8272 -0.9963 1300777 TimTec1_006637 CC1=CCC(NC1c2ccccc2)c3cnc(c(C)c3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N16 compound treatment 46080.0 -8360.0 -0.48 34840.0 -9390.0 -0.71 -0.8448 -0.9825 3211653 TimTec1_006638 COc1cccc(CNCCc2ccccc2)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N17 compound treatment 35880.0 -18600.0 -1.08 26960.0 -17300.0 -1.31 -1.6844 -0.9953 1725536 TimTec1_006639 CC(=O)N1C(C2=C(CC(CC2=O)c3ccccc3F)Nc4ccccc14)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N18 compound treatment 50280.0 -4160.0 -0.24 36360.0 -7870.0 -0.6 -0.5914 -0.9206 1400907 TimTec1_006640 CCOC(=O)Cc1csc(NCC=C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N19 compound treatment 15840.0 -38600.0 -2.24 8880.0 -35300.0 -2.68 -3.4732 -0.996 1270718 TimTec1_006641 CCOc1cccc(NC(=O)CC#N)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N20 compound treatment 46120.0 -8320.0 -0.48 33640.0 -10600.0 -0.8 -0.9074 -0.9704 1455920 TimTec1_006642 CC1CC(=O)C(C)CN1CCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N21 compound treatment 38880.0 -15600.0 -0.9 30080.0 -14100.0 -1.07 -1.3945 -0.9963 3211654 TimTec1_006643 O=C1O/C(=C/C=C\2/OC(=O)c3ccccc23)/c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N22 compound treatment 8960.0 -45500.0 -2.63 7520.0 -36700.0 -2.78 -3.8278 -0.9996 1354629 TimTec1_006644 Fc1ccccc1C(=O)N2c3ccccc3Sc4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N23 mock treatment 53360.0 -1080.0 -0.06 39640.0 -4590.0 -0.35 -0.2896 -0.821 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 N24 mock treatment 49520.0 -4920.0 -0.28 43560.0 -668.0 -0.05 -0.2371 -0.8197 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O01 compound treatment 840.0 -53600.0 -3.11 1640.0 -42600.0 -3.22 -4.4752 -0.9998 3211758 TimTec1_006645 O=C(NCCOc1ccccc1Cc2ccccc2)c3ccc4OCOc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O02 compound treatment 16480.0 -38000.0 -2.2 13840.0 -30400.0 -2.3 -3.1815 -0.9997 3088109 TimTec1_006646 CC(=O)Nc1nonc1NC(=O)C2(CC3CC4CC(C3)C2)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O03 compound treatment 33400.0 -21000.0 -1.22 32960.0 -11300.0 -0.85 -1.4649 -0.9848 3211759 TimTec1_006647 CN(C(=O)c1c(C)c(Cl)c(C)nc1Cl)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O04 compound treatment 37240.0 -17200.0 -1.0 30040.0 -14200.0 -1.07 -1.4639 -0.9993 3088110 TimTec1_006648 N=C1C(=C(N2CCOCC2)c3cc4CCCCc4n13)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O05 compound treatment 42680.0 -11800.0 -0.68 32160.0 -12100.0 -0.91 -1.1275 -0.9896 3088179 TimTec1_006649 CCOC(=O)c1ccc(NC2Nc3cc(C)nn3S2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O06 compound treatment 24080.0 -30400.0 -1.76 16720.0 -27500.0 -2.08 -2.716 -0.9965 3088181 TimTec1_006650 Fc1ccc(Nc2nc3ccccc3o2)c(F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O07 compound treatment 24400.0 -30000.0 -1.74 19680.0 -24500.0 -1.86 -2.5444 -0.9995 3088183 TimTec1_006651 CCn1c(=O)c(cc2cc(Cl)ccc12)c3ccc4ccccc4n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O08 compound treatment 49160.0 -5280.0 -0.31 37440.0 -6790.0 -0.51 -0.5795 -0.9692 3211760 TimTec1_006652 COC(=O)CC1N(CCNC1=O)C(=O)NC2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O09 compound treatment 39800.0 -14600.0 -0.85 34840.0 -9390.0 -0.71 -1.1021 -0.9961 3211761 TimTec1_006653 CCC(Sc1nc(=O)cc(N)n1CCc2ccccc2)C(=O)Nc3nc(cs3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O10 compound treatment 40720.0 -13700.0 -0.79 32840.0 -11400.0 -0.86 -1.1714 -0.9992 3088185 TimTec1_006654 CSc1nnc(s1)N2C(=O)CC(C3=C2CCCC3=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O11 compound treatment 49040.0 -5400.0 -0.31 35360.0 -8870.0 -0.67 -0.6957 -0.9395 3211762 TimTec1_006655 C1CC(CCN1)c2nc3ccccc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O12 compound treatment 45120.0 -9320.0 -0.54 36560.0 -7670.0 -0.58 -0.7921 -0.9993 1188337 TimTec1_006656 COc1ccc2cc(C#N)c(=O)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O13 compound treatment 47320.0 -7120.0 -0.41 38640.0 -5590.0 -0.42 -0.5906 -0.9999 3211763 TimTec1_006657 COC(=O)/N=c/1\[cH-][n+](no1)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O14 compound treatment 41800.0 -12600.0 -0.73 35160.0 -9070.0 -0.69 -1.003 -0.9995 3088188 TimTec1_006658 COc1ccc(cc1OC)c2c(C)c3cc(Cl)c(O)cc3oc2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O15 compound treatment 40200.0 -14200.0 -0.82 30040.0 -14200.0 -1.07 -1.3426 -0.9915 3211764 TimTec1_006659 CC12CCC3C(CC=C4CC(O)CCC34C)C2C/C(=C\c5ccc(F)cc5)/C1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O16 compound treatment 70920.0 16500.0 0.96 60400.0 16200.0 1.22 1.5409 0.9925 3088190 TimTec1_006660 CC(=O)n1c(=O)oc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O17 compound treatment 37680.0 -16800.0 -0.97 33680.0 -10500.0 -0.8 -1.251 -0.9953 3211765 TimTec1_006661 CC1(C)CC(C)(c2ccccc2)c3cccc4/C(=C\5/SC(=O)NC5=O)/C(=O)N1c43 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O18 compound treatment 52600.0 -1840.0 -0.11 37760.0 -6470.0 -0.49 -0.4214 -0.8411 1529444 TimTec1_006662 O=C(N1CCCC1)c2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O19 compound treatment 50520.0 -3920.0 -0.23 42080.0 -2150.0 -0.16 -0.2754 -0.9866 3211766 TimTec1_006663 CCOc1ccc(cc1)C(CC(=O)O)NC(=O)c2c(C)onc2c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O20 compound treatment 27120.0 -27300.0 -1.58 20840.0 -23400.0 -1.77 -2.3709 -0.9984 3088193 TimTec1_006664 CC(Sc1ccccc1)C(=O)Nc2cc(C)cc(C)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O21 compound treatment 52360.0 -2080.0 -0.12 41240.0 -2990.0 -0.23 -0.245 -0.9564 3211767 TimTec1_006665 CCCc1nc(O)c2sc(=S)n(c3ccccc3)c2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O22 compound treatment 49400.0 -5040.0 -0.29 35520.0 -8710.0 -0.66 -0.6724 -0.9328 1236651 TimTec1_006666 CCc1cc(C(=O)Cc2nc3ccccc3[nH]2)c(O)cc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O23 mock treatment 53040.0 -1400.0 -0.08 42960.0 -1270.0 -0.1 -0.125 -0.9964 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 O24 mock treatment 55880.0 1440.0 0.08 44240.0 12.5 0.0 0.0598 0.7151 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P01 compound treatment 50040.0 -4400.0 -0.25 43640.0 -588.0 -0.04 -0.2116 -0.8182 1473206 TimTec1_006667 CC1(C)CNC(=O)c2sc(nc2C1)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P02 compound treatment 200.0 -54200.0 -3.14 640.0 -43600.0 -3.3 -4.5549 -0.9997 1588991 TimTec1_006668 Cc1ccc(c2csc(Nc3ccc(cc3)C(=O)O)n2)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P03 compound treatment 45520.0 -8920.0 -0.52 29920.0 -14300.0 -1.08 -1.1311 -0.9426 1700904 TimTec1_006669 CCOC(=O)Cc1csc(NC(=O)CC)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P04 compound treatment 5040.0 -49400.0 -2.86 3120.0 -41100.0 -3.11 -4.2239 -0.9991 1292116 TimTec1_006670 Brc1ccc(cc1)c2ccc(cn2)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P05 compound treatment 27320.0 -27100.0 -1.57 21920.0 -22300.0 -1.69 -2.3049 -0.9994 1398485 TimTec1_006671 Cc1ccc(C)c(NCc2ccc3OCOc3c2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P06 compound treatment 24600.0 -29800.0 -1.73 17280.0 -26900.0 -2.04 -2.6647 -0.9966 1394993 TimTec1_006672 C(Cn1c2nc(cn2c3ccccc13)c4ccccc4)N5CCCCC5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P07 compound treatment 46040.0 -8400.0 -0.49 32200.0 -12000.0 -0.91 -0.9877 -0.9569 1307464 TimTec1_006673 CC(C)C(=O)Nc1c(O)c2ccccc2[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P08 compound treatment 14440.0 -40000.0 -2.32 11840.0 -32400.0 -2.45 -3.3721 -0.9996 1718869 TimTec1_006674 CCCC(CCC)C(=O)Nc1cccc(c1)c2nc3ccccc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P09 compound treatment 33080.0 -21400.0 -1.24 23120.0 -21100.0 -1.6 -2.0047 -0.992 3088199 TimTec1_006675 O=C(CSc1ccccc1)N2CCCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P10 compound treatment 40040.0 -14400.0 -0.83 30440.0 -13800.0 -1.04 -1.3277 -0.9938 3211768 TimTec1_006676 CC(C)C/1Oc2cc3oc(=O)ccc3cc2\C1=N/O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P11 compound treatment 6800.0 -47600.0 -2.76 6320.0 -37900.0 -2.87 -3.9805 -0.9998 1289028 TimTec1_006677 CN(C(=O)c1ccccc1)c2nc3ccccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P12 compound treatment 38680.0 -15800.0 -0.91 34400.0 -9830.0 -0.74 -1.1715 -0.9948 1729839 TimTec1_006678 OC(=O)CCCC(=O)Nc1ccccn1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P13 compound treatment 24640.0 -29800.0 -1.73 20920.0 -23300.0 -1.76 -2.4682 -0.9999 3088277 TimTec1_006679 COC(=O)C(C)Oc1nc(C)c(Br)c(OC)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P14 compound treatment 37240.0 -17200.0 -1.0 31920.0 -12300.0 -0.93 -1.3632 -0.9994 1337521 TimTec1_006680 CCCc1c(O)c2ccccc2[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P15 compound treatment 34160.0 -20300.0 -1.17 26360.0 -17900.0 -1.35 -1.787 -0.9975 3211769 TimTec1_006681 CC(C)C1C(=C(N)OC2=C1C(=O)CC(C)(C)C2)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P16 compound treatment 30440.0 -24000.0 -1.39 26680.0 -17500.0 -1.33 -1.9223 -0.9997 1376316 TimTec1_006682 OC(=O)CCNc1ncnc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P17 compound treatment 39320.0 -15100.0 -0.88 27600.0 -16600.0 -1.26 -1.5093 -0.9843 3211770 TimTec1_006683 COc1cccc(c1)N2C(=O)CN=C2Nc3nc(C)cc(C)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P18 compound treatment 36680.0 -17800.0 -1.03 34560.0 -9670.0 -0.73 -1.2449 -0.9861 3211771 TimTec1_006684 CCC1CCC2(CC1)NNC(=S)NN2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P19 compound treatment 17240.0 -37200.0 -2.16 13080.0 -31100.0 -2.36 -3.191 -0.999 1168709 TimTec1_006685 NC(=O)C1CCN(CC1)C(=O)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P20 compound treatment 37320.0 -17100.0 -0.99 32600.0 -11600.0 -0.88 -1.3236 -0.9982 1615021 TimTec1_006686 Fc1ccc2[nH]c3C(CCCc3c2c1)NC=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P21 compound treatment 45960.0 -8480.0 -0.49 39480.0 -4750.0 -0.36 -0.6014 -0.9882 3088282 TimTec1_006687 CCCCc1nnc(NC(=O)CC)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P22 compound treatment 45440.0 -9000.0 -0.52 31120.0 -13100.0 -0.99 -1.0701 -0.9548 1124526 TimTec1_006688 COc1ccc(CCNC2CCCCC2C)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P23 mock treatment 45120.0 -9320.0 -0.54 39560.0 -4670.0 -0.35 -0.6315 -0.9789 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2081 P24 mock treatment 55480.0 1040.0 0.06 37600.0 -6630.0 -0.5 -0.312 -0.6174 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A01 compound treatment 76440.0 -12900.0 -0.75 108440.0 18300.0 1.39 0.4524 0.2868 1191118 TimTec1_006689 COCC(C)NCc1cccc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A02 compound treatment 62640.0 -26700.0 -1.55 89440.0 -653.0 -0.05 -1.1299 -0.7293 1573567 TimTec1_006690 O=S(=O)(N1CCOCC1)c2ccc(cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A03 compound treatment 41080.0 -48300.0 -2.8 59360.0 -30700.0 -2.33 -3.6231 -0.9958 1587133 TimTec1_006691 CC(C)OC(=O)C1=C(C)N(C)C(=O)NC1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A04 compound treatment 76680.0 -12700.0 -0.74 91200.0 1110.0 0.08 -0.4605 -0.6225 1537360 TimTec1_006692 OCCN1C(=O)CSC21CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A05 compound treatment 64880.0 -24500.0 -1.42 99960.0 9870.0 0.75 -0.475 -0.2963 3088287 TimTec1_006693 OC(=O)CC1NC(=NC1=O)Nc2nc3ccccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A06 compound treatment 44600.0 -44800.0 -2.59 70920.0 -19200.0 -1.45 -2.8602 -0.9624 3211772 TimTec1_006694 C(Sc1ncnc2sc3CCCCc3c12)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A07 compound treatment 51960.0 -37400.0 -2.17 65360.0 -24700.0 -1.87 -2.8563 -0.9973 1192303 TimTec1_006695 OC(=O)CC1=C(CCC1=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A08 compound treatment 74600.0 -14800.0 -0.86 92320.0 2230.0 0.17 -0.4857 -0.5571 1579568 TimTec1_006696 CC(C)N1CCN(Cc2ccc(F)cc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A09 compound treatment 91080.0 1710.0 0.1 89280.0 -813.0 -0.06 0.0267 0.2286 3211773 TimTec1_006697 CCCC(=O)Nc1ccccc1OC(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A10 compound treatment 57120.0 -32200.0 -1.87 55560.0 -34500.0 -2.61 -3.1694 -0.9864 3088290 TimTec1_006698 FC(F)(F)c1cccc(NC(=S)NC(=O)c2ccccc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A11 compound treatment 77720.0 -11600.0 -0.67 84040.0 -6050.0 -0.46 -0.8011 -0.9822 1555167 TimTec1_006699 Clc1ccccc1NC(=O)CC2Nc3ccccc3NC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A12 compound treatment 79960.0 -9410.0 -0.54 92280.0 2190.0 0.17 -0.2683 -0.471 1739061 TimTec1_006700 Cc1nc2ccccc2c(O)c1CN(CC=C)CC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A13 compound treatment 78640.0 -10700.0 -0.62 83840.0 -6250.0 -0.47 -0.7741 -0.991 1541571 TimTec1_006701 COC(=O)C(CC(C)C)NC(=O)c1ccco1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A14 compound treatment 47000.0 -42400.0 -2.45 47200.0 -42900.0 -3.25 -4.0315 -0.9905 1353905 TimTec1_006702 COc1ccc(cc1OC)C2(CCc3[nH]c4ccccc4c3C2)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A15 compound treatment 75240.0 -14100.0 -0.82 79880.0 -10200.0 -0.77 -1.1254 -0.9996 1788321 TimTec1_006703 Nc1ccc2[nH]c(Cc3ccccc3)nc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A16 compound treatment 84800.0 -4570.0 -0.26 93200.0 3110.0 0.24 -0.0208 -0.0587 1538142 TimTec1_006704 CC(=O)Nc1ccc(cc1)S(=O)(=O)CCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A17 compound treatment 83080.0 -6290.0 -0.36 79920.0 -10200.0 -0.77 -0.802 -0.9415 3088294 TimTec1_006705 Brc1ccc(cc1)C(=O)COC(=O)c2cn(nc2c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A18 compound treatment 81680.0 -7690.0 -0.45 92680.0 2590.0 0.2 -0.1764 -0.3626 1281666 TimTec1_006706 CC(C)(C)C(=O)Cn1c(NCCO)nc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A19 compound treatment 75640.0 -13700.0 -0.8 89560.0 -533.0 -0.04 -0.5909 -0.742 1640157 TimTec1_006707 CCOc1ccc(cc1)C(=O)OCCC2CCCN3CCCCC23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A20 compound treatment 93920.0 4550.0 0.26 87520.0 -2570.0 -0.19 0.0488 0.149 1913968 TimTec1_006708 Clc1ccc(NCn2nnc3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A21 compound treatment 34520.0 -54800.0 -3.18 44720.0 -45400.0 -3.43 -4.6755 -0.9992 1634555 TimTec1_006709 Cc1cccc(NC(=O)c2cc3ccccc3oc2=O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A22 compound treatment 92160.0 2790.0 0.16 103160.0 13100.0 0.99 0.8139 0.812 1298020 TimTec1_006710 CC1=CCC(C(C1)C(=O)Nc2nc3ccc(cc3s2)S(=O)(=O)C)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A23 mock treatment 86600.0 -2770.0 -0.16 99480.0 9390.0 0.71 0.3891 0.5342 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 A24 mock treatment 98760.0 9390.0 0.54 87640.0 -2450.0 -0.19 0.2536 0.4409 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B01 compound treatment 74960.0 -14400.0 -0.83 96840.0 6750.0 0.51 -0.2291 -0.2341 1702916 TimTec1_006711 CCC(=O)Nc1sc(C(=O)N2CCCCC2)c(C)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B02 compound treatment 68720.0 -20600.0 -1.2 98360.0 8270.0 0.63 -0.4033 -0.2988 3211774 TimTec1_006712 Cc1ccccc1CNCCc2c[nH]c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B03 compound treatment 62720.0 -26600.0 -1.54 91920.0 1830.0 0.14 -0.9939 -0.6412 1742610 TimTec1_006713 Cc1c(Cl)cccc1NC(=O)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B04 compound treatment 69960.0 -19400.0 -1.12 98760.0 8670.0 0.66 -0.3311 -0.2544 1433621 TimTec1_006714 CN(C)c1nc2c(N)ncnc2[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B05 compound treatment 53320.0 -36000.0 -2.09 86680.0 -3410.0 -0.26 -1.6594 -0.7886 3211866 TimTec1_006715 O=S(=O)(CCC#N)c1ccc(Oc2ccc(cc2)S(=O)(=O)CCC#N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B06 compound treatment 40440.0 -48900.0 -2.83 62000.0 -28100.0 -2.13 -3.5081 -0.99 3088376 TimTec1_006716 CC(Sc1ccccc1)C(=O)Nc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B07 compound treatment 44840.0 -44500.0 -2.58 63040.0 -27100.0 -2.05 -3.2721 -0.9935 1180218 TimTec1_006717 OC(=O)c1cc2c(ccc3ccccc32)oc1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B08 compound treatment 16920.0 -72400.0 -4.2 32000.0 -58100.0 -4.4 -6.0774 -0.9997 3088379 TimTec1_006718 CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)N2CCN=C2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B09 compound treatment 49680.0 -39700.0 -2.3 65080.0 -25000.0 -1.89 -2.9647 -0.9953 1330797 TimTec1_006719 Cc1ccc(OCC(=O)Nc2ccccc2C(=O)N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B10 compound treatment 73360.0 -16000.0 -0.93 92760.0 2670.0 0.2 -0.513 -0.5405 3211867 TimTec1_006720 O/N=C/1\CCCc2c1nc(c3ccccc3Cl)n2O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B11 compound treatment 89200.0 -166.0 -0.01 92200.0 2110.0 0.16 0.106 0.6632 1713095 TimTec1_006721 CNC(=O)CC1Nc2ccccc2NC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B12 compound treatment 63880.0 -25500.0 -1.48 77760.0 -12300.0 -0.93 -1.7042 -0.9755 1487671 TimTec1_006722 Cc1ccc(C)c(NC(=O)c2ccco2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B13 compound treatment 81560.0 -7810.0 -0.45 105760.0 15700.0 1.19 0.5188 0.4087 1579293 TimTec1_006723 CCC(C)N1CCN(CC2CCC=CC2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B14 compound treatment 27440.0 -61900.0 -3.59 42000.0 -48100.0 -3.64 -5.1111 -1.0 3211868 TimTec1_006724 FC(F)(F)c1nn(CC(=O)N2CCCc3ccccc23)c4CCCCc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B15 compound treatment 86600.0 -2770.0 -0.16 95440.0 5350.0 0.4 0.1729 0.3971 3088384 TimTec1_006725 O/N=C/1\CCC2CN(CC2C1)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B16 compound treatment 70000.0 -19400.0 -1.12 82240.0 -7850.0 -0.59 -1.2137 -0.9559 3211869 TimTec1_006726 CCOC(=O)CSc1ncnc2sc(C)c(C)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B17 compound treatment 2040.0 -87300.0 -5.06 2320.0 -87800.0 -6.64 -8.2756 -0.991 1621335 TimTec1_006727 Cc1cc(SCC(=O)Nc2ccccc2)c3ccccc3n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B18 compound treatment 72440.0 -16900.0 -0.98 80720.0 -9370.0 -0.71 -1.1951 -0.9874 3088387 TimTec1_006728 CSC1=C(C#N)C(CC(=O)N1)c2ccc(cc2)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B19 compound treatment 88480.0 -886.0 -0.05 93040.0 2950.0 0.22 0.1214 0.5305 1235770 TimTec1_006729 NC(=O)C1CCN(CCC(=O)Nc2ccccc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B20 compound treatment 85800.0 -3570.0 -0.21 95240.0 5150.0 0.39 0.1294 0.2934 1483335 TimTec1_006730 COc1ccc(NC(=O)CC2(Cc3ccccc3)CCOC(C)(C)C2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B21 compound treatment 92240.0 2870.0 0.17 101160.0 11100.0 0.84 0.7101 0.8314 1160668 TimTec1_006731 CC(C)C1(CN2CC3CN(C1)CC2)C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B22 compound treatment 89120.0 -246.0 -0.01 94800.0 4710.0 0.36 0.2419 0.6782 1622689 TimTec1_006732 COc1ccc2NC(C3CC=CC3c2c1)c4cc5OCOc5cc4Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B23 mock treatment 92640.0 3270.0 0.19 101240.0 11100.0 0.84 0.7308 0.845 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 B24 mock treatment 87600.0 -1770.0 -0.1 100480.0 10400.0 0.79 0.4836 0.6099 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C01 compound treatment 66360.0 -23000.0 -1.33 83680.0 -6410.0 -0.49 -1.2858 -0.9064 1335975 TimTec1_006733 C(CN1CCOCC1)Cn2c(cn3c2nc4ccccc43)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C02 compound treatment 62800.0 -26600.0 -1.54 91440.0 1350.0 0.1 -1.0163 -0.6588 1454078 TimTec1_006734 COC(=O)c1ccc(cc1)c2nc3ccccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C03 compound treatment 72840.0 -16500.0 -0.96 114440.0 24300.0 1.84 0.6261 0.3015 1235834 TimTec1_006735 COc1cccc(CN2CCN(CC2)C(C)C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C04 compound treatment 73320.0 -16000.0 -0.93 99040.0 8950.0 0.68 -0.1785 -0.1552 1253454 TimTec1_006736 Cc1ccc(O)c(CCc2ccc(O)cc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C05 compound treatment 28280.0 -61100.0 -3.54 48920.0 -41200.0 -3.12 -4.7063 -0.998 3211870 TimTec1_006737 CN(Cc1ccccc1)C(=O)c2cc3nc(cc(n3n2)C(F)(F)F)c4ccc(C)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C06 compound treatment 67440.0 -21900.0 -1.27 97200.0 7110.0 0.54 -0.5179 -0.3754 1784507 TimTec1_006738 [O-][n+]1c2CCc3nonc3-c2nn1c4ccccc4Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C07 compound treatment 11360.0 -78000.0 -4.52 22720.0 -67400.0 -5.1 -6.8018 -0.9982 1708265 TimTec1_006739 Clc1ccc(cc1)C(=O)NCC2(CCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C08 compound treatment 67840.0 -21500.0 -1.25 94760.0 4670.0 0.35 -0.6321 -0.4876 1294485 TimTec1_006740 COC(=O)c1sc2nc(cc(c3ccccc3)c2c1N)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C09 compound treatment 63880.0 -25500.0 -1.48 77320.0 -12800.0 -0.97 -1.7278 -0.9789 1189050 TimTec1_006741 Brc1cc(Br)c2oc(=O)c(cc2c1)C(=O)OCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C10 compound treatment 70920.0 -18400.0 -1.07 93280.0 3190.0 0.24 -0.5851 -0.5341 1225819 TimTec1_006742 Brc1ccc(cc1)C(=O)Oc2ccc3oc(=O)sc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C11 compound treatment 88040.0 -1330.0 -0.08 97760.0 7670.0 0.58 0.356 0.6082 3211871 TimTec1_006743 OC(=O)c1cc(nc2ccc(Br)cc12)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C12 compound treatment 88080.0 -1290.0 -0.07 95080.0 4990.0 0.38 0.2142 0.5568 1285755 TimTec1_006744 OC(=O)c1ccc(Nc2nc(cs2)c3ccc(Cl)c(Cl)c3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C13 compound treatment 79000.0 -10400.0 -0.6 73720.0 -16400.0 -1.24 -1.301 -0.9447 1580452 TimTec1_006745 O(c1ccccc1)c2nnc(c3ccccc3)c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C14 compound treatment 48720.0 -40600.0 -2.35 60440.0 -29700.0 -2.24 -3.2523 -0.9997 1550487 TimTec1_006746 CC(=O)N1CC(C=C(C)C1c2ccccc2)c3cnc(c(C)c3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C15 compound treatment 48800.0 -40600.0 -2.35 56880.0 -33200.0 -2.51 -3.4396 -0.9994 1546076 TimTec1_006747 COc1ccc2n(C)c(C)c(C(=O)CSc3ccccc3)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C16 compound treatment 82720.0 -6650.0 -0.39 91240.0 1150.0 0.09 -0.2109 -0.5342 3211872 TimTec1_006748 COc1ccc(CNCCC2(Cc3ccccc3)CC(C)N(C)CC2C)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C17 compound treatment 63520.0 -25800.0 -1.5 69480.0 -20600.0 -1.56 -2.1622 -0.9998 3088471 TimTec1_006749 N#Cc1c(SCc2ccccc2C#N)nsc1SCc3ccccc3C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C18 compound treatment 22720.0 -66600.0 -3.86 26040.0 -64100.0 -4.85 -6.1587 -0.9936 1128012 TimTec1_006750 CC(C)CC(=O)NC(c1ccccc1)c2c(O)ccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C19 compound treatment 86480.0 -2890.0 -0.17 95600.0 5510.0 0.42 0.1765 0.393 1522229 TimTec1_006751 COc1ccccc1C2C3=C(CCCC3=O)N(CC(=O)O)C4=C2C(=O)CCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C20 compound treatment 85600.0 -3770.0 -0.22 94240.0 4150.0 0.31 0.0677 0.177 3211873 TimTec1_006752 CC(C)NC(=O)CSCc1ccc(Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C21 compound treatment 83640.0 -5730.0 -0.33 93720.0 3630.0 0.27 -0.0405 -0.0939 1278138 TimTec1_006753 NC(=O)c1cc(N)ccc1N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C22 compound treatment 94400.0 5030.0 0.29 93880.0 3790.0 0.29 0.4089 1.0 1148287 TimTec1_006754 CC(C)C1=CC2=C(CC(C)(C)CC2=O)OC1N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C23 mock treatment 96040.0 6670.0 0.39 97360.0 7270.0 0.55 0.6624 0.9851 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 C24 mock treatment 92920.0 3550.0 0.21 96040.0 5950.0 0.45 0.4639 0.9372 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D01 compound treatment 43080.0 -46300.0 -2.68 58920.0 -31200.0 -2.36 -3.5648 -0.998 1357090 TimTec1_006755 Cc1ccc2n3CCN(CC#N)C4CCc(c43)c(=O)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D02 compound treatment 58040.0 -31300.0 -1.81 87600.0 -2490.0 -0.19 -1.4168 -0.7764 3088476 TimTec1_006756 COc1ccc(cc1OC)c2cc(nc(N)c2C#N)c3ccc(Cl)c(Cl)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D03 compound treatment 36440.0 -52900.0 -3.07 67240.0 -22900.0 -1.73 -3.3915 -0.9633 1669245 TimTec1_006757 C(C#Cc1ccccc1)N2CCN(CC2)C(c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D04 compound treatment 53640.0 -35700.0 -2.07 82680.0 -7410.0 -0.56 -1.8604 -0.8675 1279830 TimTec1_006758 O=c1cc(N2CCCC2)c3ccccc3o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D05 compound treatment 67480.0 -21900.0 -1.27 82880.0 -7210.0 -0.55 -1.2827 -0.9291 3211874 TimTec1_006759 O=C1C(C(=O)c2ccccc12)c3ccc4ccccc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D06 compound treatment 53000.0 -36400.0 -2.11 71040.0 -19100.0 -1.44 -2.5096 -0.9829 1228770 TimTec1_006760 Fc1ccc(cc1)C(CCCN2CCN3CCCCCC3C2)c4ccc(F)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D07 compound treatment 68320.0 -21000.0 -1.22 106600.0 16500.0 1.25 0.0213 0.0122 1294456 TimTec1_006761 OC(=O)c1ccccc1C(=O)N(Cc2ccccc2)Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D08 compound treatment 51120.0 -38200.0 -2.22 89760.0 -333.0 -0.03 -1.5847 -0.7151 1150523 TimTec1_006762 O=C1CC(CC2=C1C(Nc3ccccc3N2)c4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D09 compound treatment 43520.0 -45800.0 -2.66 77040.0 -13100.0 -0.99 -2.5769 -0.9093 3088554 TimTec1_006763 COc1ccc2c(c(C)oc2c1)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D10 compound treatment 83760.0 -5610.0 -0.32 95640.0 5550.0 0.42 0.0672 0.1266 3088557 TimTec1_006764 CC(=O)Nc1ccc2n(C)c(C)nc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D11 compound treatment 80480.0 -8890.0 -0.51 90120.0 27.1 0.0 -0.3626 -0.7043 1170616 TimTec1_006765 Cc1ccccc1NC(=O)CC2Nc3ccccc3NC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D12 compound treatment 65000.0 -24400.0 -1.41 80680.0 -9410.0 -0.71 -1.5021 -0.9499 1215173 TimTec1_006766 COc1ccccc1NC(=O)C2=C(C)NC3=C(C2c4ccc(Cl)cc4Cl)C(=O)CC(C)(C)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D13 compound treatment 68920.0 -20400.0 -1.18 88640.0 -1450.0 -0.11 -0.9154 -0.7694 1235033 TimTec1_006767 Cc1c(oc2ccccc12)C(=O)OCCN3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D14 compound treatment 80520.0 -8850.0 -0.51 95640.0 5550.0 0.42 -0.0655 -0.0989 1338758 TimTec1_006768 CC(C)Oc1ccc(CNC2CCOC(C)(C)C2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D15 compound treatment 45440.0 -43900.0 -2.54 57480.0 -32600.0 -2.47 -3.5451 -0.9999 3211875 TimTec1_006769 CCCOc1nc(cc(n1)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D16 compound treatment 53640.0 -35700.0 -2.07 67720.0 -22400.0 -1.69 -2.6611 -0.995 3211876 TimTec1_006770 Cc1sc2ncnc(SCC(=O)Nc3cc(C)ccc3C)c2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D17 compound treatment 77320.0 -12000.0 -0.7 89120.0 -973.0 -0.07 -0.5456 -0.7774 1122485 TimTec1_006771 Cc1ccc(cc1)c2cn3c(nc4ccccc43)n2CCCN5CCCCC5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D18 compound treatment 46960.0 -42400.0 -2.46 56120.0 -34000.0 -2.57 -3.5557 -0.9997 1249464 TimTec1_006772 COC(=O)c1ccc(cc1)C2Nc3c(cccc3C4C=CCC42)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D19 compound treatment 88920.0 -446.0 -0.03 95640.0 5550.0 0.42 0.2786 0.6623 1389916 TimTec1_006773 CC1CCN(CCC(=O)Nc2ccc3OCOc3c2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D20 compound treatment 54560.0 -34800.0 -2.02 60320.0 -29800.0 -2.25 -3.0195 -0.9985 1429288 TimTec1_006774 CC(C)c1ccc(OCC(=O)NC(C)c2ccccc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D21 compound treatment 79880.0 -9490.0 -0.55 98920.0 8830.0 0.67 0.0838 0.0969 1645937 TimTec1_006775 COc1cc(ccc1O)C(C#N)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D22 compound treatment 46760.0 -42600.0 -2.47 55480.0 -34600.0 -2.62 -3.5981 -0.9996 3088562 TimTec1_006776 COc1ccc(Cl)cc1C(=O)CSc2cc(C)c3ccccc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D23 mock treatment 93680.0 4310.0 0.25 97120.0 7030.0 0.53 0.5528 0.9407 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 D24 mock treatment 99760.0 10400.0 0.6 94640.0 4550.0 0.34 0.6692 0.9648 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E01 compound treatment 67000.0 -22400.0 -1.3 98040.0 7950.0 0.6 -0.4909 -0.3436 1193138 TimTec1_006777 COC(=O)c1cc(CN2CCN(C)CC2)ccc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E02 compound treatment 70760.0 -18600.0 -1.08 104760.0 14700.0 1.11 0.0228 0.0147 1776719 TimTec1_006778 Oc1[nH]c(=O)c(C#N)c2CCN(Cc3ccccc3)Cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E03 compound treatment 57600.0 -31800.0 -1.84 94840.0 4750.0 0.36 -1.0473 -0.5585 1574650 TimTec1_006779 CC(C)CNC(=O)c1cccc(NC(=O)c2ccco2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E04 compound treatment 64280.0 -25100.0 -1.45 91240.0 1150.0 0.09 -0.9663 -0.6637 1646030 TimTec1_006780 CC(Nc1ncnc2ccccc12)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E05 compound treatment 64560.0 -24800.0 -1.44 86640.0 -3450.0 -0.26 -1.2011 -0.8222 1655517 TimTec1_006781 CCCCC1(CC(C)(OC1=O)c2csc(N)n2)C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E06 compound treatment 59120.0 -30200.0 -1.75 98160.0 8070.0 0.61 -0.8073 -0.4351 1315927 TimTec1_006782 CN1CCCC(C1)OC(=O)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E07 compound treatment 50720.0 -38600.0 -2.24 86600.0 -3490.0 -0.26 -1.7702 -0.7851 1216871 TimTec1_006783 CCCN(Cc1ccccc1)S(=O)(=O)c2ccc(cc2)N3C(=O)CCC3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E08 compound treatment 49360.0 -40000.0 -2.32 77480.0 -12600.0 -0.95 -2.3141 -0.9231 1623058 TimTec1_006784 COc1ccc(Cl)cc1Nc2nc3cc(C)ccc3cc2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E09 compound treatment 88240.0 -1130.0 -0.07 103640.0 13500.0 1.03 0.679 0.6608 3211956 TimTec1_006785 OC(=O)C1CC=CCC1C(=O)Nc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E10 compound treatment 75400.0 -14000.0 -0.81 89760.0 -333.0 -0.03 -0.59 -0.7288 1216589 TimTec1_006786 COc1ccc(cc1)N(C=O)C(C(=O)Nc2c(C)cccc2C)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E11 compound treatment 57560.0 -31800.0 -1.84 62800.0 -27300.0 -2.07 -2.7639 -0.9984 1547982 TimTec1_006787 C=CCC1(CCCCC1)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E12 compound treatment 79280.0 -10100.0 -0.58 100120.0 10000.0 0.76 0.1235 0.1289 1164189 TimTec1_006788 Cc1nc(N)nc(O)c1Oc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E13 compound treatment 84960.0 -4410.0 -0.26 90880.0 787.0 0.06 -0.1384 -0.5279 1614806 TimTec1_006789 CCC1(C)CC(CC(=O)OC(C)CN(C)C)(CCO1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E14 compound treatment 23760.0 -65600.0 -3.8 34960.0 -55100.0 -4.17 -5.6387 -0.9989 1071490 TimTec1_006790 COc1ccc(CCNC(=O)C(c2ccccc2)c3ccccc3)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E15 compound treatment 59040.0 -30300.0 -1.76 61920.0 -28200.0 -2.13 -2.7503 -0.9954 1306668 TimTec1_006791 COc1ccc(C)cc1NCc2ccccc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E16 compound treatment 37960.0 -51400.0 -2.98 44760.0 -45300.0 -3.43 -4.5324 -0.9975 1737928 TimTec1_006792 CCc1cc(C(=O)Cc2nc3ccccc3s2)c(O)cc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E17 compound treatment 26800.0 -62600.0 -3.62 31680.0 -58400.0 -4.42 -5.6897 -0.9951 1514112 TimTec1_006793 Clc1ccccc1CNC(=O)C2(CCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E18 compound treatment 80520.0 -8850.0 -0.51 79960.0 -10100.0 -0.77 -0.9048 -0.9808 3088573 TimTec1_006794 CNCC(O)Cn1c2CCCCc2c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E19 compound treatment 55080.0 -34300.0 -1.99 66880.0 -23200.0 -1.76 -2.6471 -0.9981 1478401 TimTec1_006795 CCCC(=O)Nc1sc(C(=O)Nc2cccc(C)c2C)c(C)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E20 compound treatment 79880.0 -9490.0 -0.55 83720.0 -6370.0 -0.48 -0.7297 -0.9979 1241738 TimTec1_006796 COc1ccc(CCNC(=O)C(C)(C)C)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E21 compound treatment 91880.0 2510.0 0.15 91720.0 1630.0 0.12 0.1901 0.9965 3087516 TimTec1_006797 CC(=O)Nc1c(O)nc(SCC(=O)N2CCOCC2)nc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E22 compound treatment 80800.0 -8570.0 -0.5 95840.0 5750.0 0.44 -0.0433 -0.0657 1605940 TimTec1_006798 S=C(NCC1CCCO1)NC2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E23 mock treatment 102120.0 12800.0 0.74 102880.0 12800.0 0.97 1.2069 0.9911 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 E24 mock treatment 93960.0 4590.0 0.27 96680.0 6590.0 0.5 0.5408 0.9568 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F01 compound treatment 26920.0 -62400.0 -3.62 42520.0 -47600.0 -3.6 -5.1046 -1.0 1786318 TimTec1_006799 Cc1ccc(SCC(=O)Nc2cccnc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F02 compound treatment 61520.0 -27800.0 -1.61 96520.0 6430.0 0.49 -0.7968 -0.4729 3087518 TimTec1_006800 Cc1ccc2nc(Nc3cccc(c3)C(F)(F)F)c(C#N)cc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F03 compound treatment 51360.0 -38000.0 -2.2 80840.0 -9250.0 -0.7 -2.0523 -0.8882 1787075 TimTec1_006801 O=C(OCCN1CCOCC1)C(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F04 compound treatment 50960.0 -38400.0 -2.23 97200.0 7110.0 0.54 -1.193 -0.5211 3211957 TimTec1_006802 Cc1ccc(cc1)S(=O)(=O)C(CC(=O)c2ccco2)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F05 compound treatment 39800.0 -49600.0 -2.87 60400.0 -29700.0 -2.25 -3.6199 -0.9926 3087520 TimTec1_006803 COc1nc(nc2ccccc12)c3ccc(Cl)cc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F06 compound treatment 57200.0 -32200.0 -1.86 87840.0 -2250.0 -0.17 -1.4384 -0.7686 1271720 TimTec1_006804 Cc1ccccc1OCc2nnc(N)s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F07 compound treatment 62400.0 -27000.0 -1.56 88160.0 -1930.0 -0.15 -1.2082 -0.77 1606230 TimTec1_006805 Cc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F08 compound treatment 66800.0 -22600.0 -1.31 97440.0 7350.0 0.56 -0.5313 -0.3739 1628397 TimTec1_006806 Cn1c(SCC(=O)NC2CCCCC2)nc3n(C)c(=O)n(C)c(=O)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F09 compound treatment 13560.0 -75800.0 -4.39 21200.0 -68900.0 -5.21 -6.7931 -0.9964 1514196 TimTec1_006807 OC(=O)c1cccc(NC(=O)c2cc3ccccc3o2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F10 compound treatment 63760.0 -25600.0 -1.48 77240.0 -12900.0 -0.97 -1.737 -0.9791 1327645 TimTec1_006808 Nc1cccc(c1)C(=O)Nc2nccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F11 compound treatment 83120.0 -6250.0 -0.36 90560.0 467.0 0.04 -0.2309 -0.635 1408003 TimTec1_006809 CC(CC(=O)O)n1nnc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F12 compound treatment 76880.0 -12500.0 -0.72 92120.0 2030.0 0.15 -0.403 -0.545 3211958 TimTec1_006810 NC(=O)Cn1nc(c2CCCCc21)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F13 compound treatment 89200.0 -166.0 -0.01 85640.0 -4450.0 -0.34 -0.2451 -0.727 1545556 TimTec1_006811 CNCC(O)CN1CCN(CC1)c2ccccc2OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F14 compound treatment 71480.0 -17900.0 -1.04 88680.0 -1410.0 -0.11 -0.8084 -0.776 1280870 TimTec1_006812 O=S1OCC(COc2cccc3ccccc23)O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F15 compound treatment 45320.0 -44000.0 -2.55 54960.0 -35100.0 -2.66 -3.6849 -0.9998 3087526 TimTec1_006813 CCc1ccc(nc1)c2ccc(Br)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F16 compound treatment 57120.0 -32200.0 -1.87 66120.0 -24000.0 -1.81 -2.6042 -0.9999 1386778 TimTec1_006814 COc1cc(ccc1OCC(=O)Nc2ccccc2C)C3C(=C(N)OC4=C3C(=O)CC(C)(C)C4)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F17 compound treatment 81120.0 -8250.0 -0.48 79040.0 -11100.0 -0.84 -0.9294 -0.9647 1919073 TimTec1_006815 CC(C)(C)S(=O)(=O)c1cccs1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F18 compound treatment 62920.0 -26400.0 -1.53 77000.0 -13100.0 -0.99 -1.7842 -0.9778 1656061 TimTec1_006816 COc1ccc(cc1)C2CC(=O)NC(=C2C#N)SCC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F19 compound treatment 78320.0 -11000.0 -0.64 83080.0 -7010.0 -0.53 -0.8279 -0.9957 1199433 TimTec1_006817 Cc1ccc2n3CCN(CC(O)CN4CCCC4)C5CCCc(c53)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F20 compound treatment 67520.0 -21800.0 -1.27 76840.0 -13300.0 -1.0 -1.6043 -0.9934 1221052 TimTec1_006818 Oc1ccc(NC(=O)c2c(O)c3ccccc3[nH]c2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F21 compound treatment 87640.0 -1730.0 -0.1 93240.0 3150.0 0.24 0.0977 0.3782 1475350 TimTec1_006819 CCN1N=C(CCC1=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F22 compound treatment 76480.0 -12900.0 -0.75 88600.0 -1490.0 -0.11 -0.6078 -0.805 1392419 TimTec1_006820 Cc1ccc(OCC(=O)N2CCN(CC3CC4CC3C=C4)CC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F23 mock treatment 94640.0 5270.0 0.31 96200.0 6110.0 0.46 0.5429 0.9798 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 F24 mock treatment 95720.0 6350.0 0.37 90520.0 427.0 0.03 0.2832 0.7663 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G01 compound treatment 50120.0 -39200.0 -2.27 79480.0 -10600.0 -0.8 -2.1759 -0.9023 1567385 TimTec1_006821 COc1ccc(CNc2cc(C)cc(C)c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G02 compound treatment 29080.0 -60300.0 -3.49 61040.0 -29100.0 -2.2 -4.0248 -0.9751 3087531 TimTec1_006822 CC1CC2(CCCCC2)N(C(=O)C)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G03 compound treatment 44800.0 -44600.0 -2.58 70960.0 -19100.0 -1.45 -2.8499 -0.9626 3211959 TimTec1_006823 Cc1sc2ncnc(SCc3ccc(C)cc3)c2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G04 compound treatment 33080.0 -56300.0 -3.26 64240.0 -25900.0 -1.96 -3.6897 -0.9702 1130050 TimTec1_006824 CCC(C)OC(=O)C1=C(C)NC2=C(C1c3ccc(C)o3)C(=O)CC(C2)c4ccc(OC)c(OC)c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G05 compound treatment 57000.0 -32400.0 -1.88 89400.0 -693.0 -0.05 -1.3631 -0.7266 1376669 TimTec1_006825 CC(Cc1ccccc1)NC(=O)C2CCCNC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G06 compound treatment 50640.0 -38700.0 -2.24 82800.0 -7290.0 -0.55 -1.9769 -0.8556 1285783 TimTec1_006826 OC(=O)C1C(C2CC1C=C2)C(=O)Nc3ccccc3O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G07 compound treatment 63040.0 -26300.0 -1.53 90560.0 467.0 0.04 -1.0535 -0.6905 1630547 TimTec1_006827 OCC(NC(=O)c1cncc(O)c1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G08 compound treatment 32000.0 -57400.0 -3.32 60400.0 -29700.0 -2.25 -3.9395 -0.9819 1290578 TimTec1_006828 NC1=C(C#N)C2(CCCCC2)C(=C(N1)SCc3ccccc3)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G09 compound treatment 56760.0 -32600.0 -1.89 78400.0 -11700.0 -0.89 -1.9617 -0.9403 1492451 TimTec1_006829 O=C(CN(C1CCCCC1)C(=O)c2ccccc2)Nc3nc(cs3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G10 compound treatment 86720.0 -2650.0 -0.15 89360.0 -733.0 -0.06 -0.1476 -0.9055 1506265 TimTec1_006830 CC(CN1CCCCC1)OC(=O)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G11 compound treatment 77080.0 -12300.0 -0.71 84000.0 -6090.0 -0.46 -0.8295 -0.9779 1676645 TimTec1_006831 Clc1cccc(CN2CCN(CC2)C(=O)c3cccs3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G12 compound treatment 76600.0 -12800.0 -0.74 87800.0 -2290.0 -0.17 -0.6457 -0.8499 1179682 TimTec1_006832 CCOc1ccc2nc3CCCCc3c(C(=O)O)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G13 compound treatment 49320.0 -40000.0 -2.32 63360.0 -26700.0 -2.02 -3.0715 -0.9977 3212025 TimTec1_006833 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccccc3Br)sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G14 compound treatment 45600.0 -43800.0 -2.54 57760.0 -32300.0 -2.45 -3.5236 -0.9998 1719128 TimTec1_006834 CCCCC1CN2CCc3c([nH]c4ccccc34)C2(C)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G15 compound treatment 72440.0 -16900.0 -0.98 87240.0 -2850.0 -0.22 -0.8461 -0.8426 1540479 TimTec1_006835 CNC(=O)c1c(O)c2ccccc2n(C)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G16 compound treatment 33320.0 -56000.0 -3.25 44520.0 -45600.0 -3.45 -4.7354 -0.9995 3087554 TimTec1_006836 CC(C)C(=O)Nc1cccc2nsnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G17 compound treatment 75240.0 -14100.0 -0.82 77080.0 -13000.0 -0.99 -1.2752 -0.9958 1681031 TimTec1_006837 CCC(C)N1CCN(CC1)C(=O)C(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G18 compound treatment 93160.0 3790.0 0.22 91520.0 1430.0 0.11 0.2318 0.9465 1312686 TimTec1_006838 CCOC(=O)c1sc(nc1C)N2C(C(=C(O)C2=O)C(=O)c3ccc(OC)c(C)c3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G19 compound treatment 65040.0 -24300.0 -1.41 73960.0 -16100.0 -1.22 -1.8601 -0.9974 3087555 TimTec1_006839 CC(=O)n1c(=O)n(C(=O)C)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G20 compound treatment 71400.0 -18000.0 -1.04 85200.0 -4890.0 -0.37 -0.9979 -0.9032 3212026 TimTec1_006840 COc1ccc(CNCCC2(CCOC(C)(C)C2)c3ccccc3)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G21 compound treatment 74840.0 -14500.0 -0.84 90960.0 867.0 0.07 -0.5487 -0.65 1426762 TimTec1_006841 CC(=C)CNCC1OCCc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G22 compound treatment 55920.0 -33400.0 -1.94 65800.0 -24300.0 -1.84 -2.6705 -0.9997 1432528 TimTec1_006842 Fc1ccccc1C(=O)N2CCC(Cc3ccccc3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G23 mock treatment 85480.0 -3890.0 -0.23 94320.0 4230.0 0.32 0.067 0.1713 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 G24 mock treatment 89760.0 394.0 0.02 88600.0 -1490.0 -0.11 -0.0638 -0.5532 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H01 compound treatment 67440.0 -21900.0 -1.27 103120.0 13000.0 0.99 -0.201 -0.125 1714695 TimTec1_006843 Nc1nncn1C(=O)c2ccccc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H02 compound treatment 51760.0 -37600.0 -2.18 80440.0 -9650.0 -0.73 -2.0573 -0.8952 3087557 TimTec1_006844 Cc1sc(NC(=O)c2cccc(C)c2)c(C#N)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H03 compound treatment 63840.0 -25500.0 -1.48 104480.0 14400.0 1.09 -0.2757 -0.1501 1542138 TimTec1_006845 OC(=O)CC(NC(=O)c1ccccc1Cl)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H04 compound treatment 52960.0 -36400.0 -2.11 78160.0 -11900.0 -0.9 -2.1302 -0.9284 1720177 TimTec1_006846 Brc1ccc(o1)C(=O)Nc2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H05 compound treatment 57200.0 -32200.0 -1.86 91120.0 1030.0 0.08 -1.2628 -0.677 1733502 TimTec1_006847 COc1ccccc1NC(=O)Cc2csc(N)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H06 compound treatment 37480.0 -51900.0 -3.01 59880.0 -30200.0 -2.29 -3.7428 -0.9909 1681208 TimTec1_006848 O=C1OC2(C3CCCC2C31Sc4ccccc4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H07 compound treatment 50240.0 -39100.0 -2.27 87280.0 -2810.0 -0.21 -1.7535 -0.7701 1675342 TimTec1_006849 CC1(C)Cc2c(CO1)sc3c2c(=O)n(Cc4ccccc4)c5nncn53 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H08 compound treatment 50560.0 -38800.0 -2.25 81440.0 -8650.0 -0.65 -2.053 -0.8767 3212027 TimTec1_006850 CC(C)CCn1c(nc2ccccc12)C(C)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H09 compound treatment 77280.0 -12100.0 -0.7 92240.0 2150.0 0.16 -0.3802 -0.5289 1775014 TimTec1_006851 Oc1c(C(=O)NCCN2CCOCC2)c(=O)[nH]c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H10 compound treatment 43600.0 -45800.0 -2.65 62480.0 -27600.0 -2.09 -3.3529 -0.9931 1635890 TimTec1_006852 CCCCC(=O)Nc1sc2CCCCc2c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H11 compound treatment 81800.0 -7570.0 -0.44 83000.0 -7090.0 -0.54 -0.6896 -0.9949 3087563 TimTec1_006853 OC(=O)c1ccc(CSCc2ccccc2)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H12 compound treatment 31080.0 -58300.0 -3.38 39920.0 -50200.0 -3.8 -5.0733 -0.9983 3212028 TimTec1_006854 C(Cc1nc2ccccc2s1)c3nc4ccccc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H13 compound treatment 44400.0 -45000.0 -2.61 45880.0 -44200.0 -3.35 -4.2086 -0.9923 1288163 TimTec1_006855 CCc1nc(NCc2ccccc2)c(C#N)c3CC(C)(C)OCc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H14 compound treatment 63240.0 -26100.0 -1.51 74080.0 -16000.0 -1.21 -1.9274 -0.9939 1574023 TimTec1_006856 O=C(CSCc1ccccc1)Nc2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H15 compound treatment 72560.0 -16800.0 -0.97 72000.0 -18100.0 -1.37 -1.6569 -0.986 1780586 TimTec1_006857 COc1ccc(cc1OC)/C(=C/N2CCOCC2)/C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H16 compound treatment 36560.0 -52800.0 -3.06 45000.0 -45100.0 -3.41 -4.5769 -0.9985 1294188 TimTec1_006858 CCOC(=O)CSC1=C(C#N)C(C(=C(C)N1)C(=O)Nc2ccccc2OC)c3ccccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H17 compound treatment 75120.0 -14200.0 -0.83 89640.0 -453.0 -0.03 -0.6079 -0.7358 1244483 TimTec1_006859 O=C(Nc1ccccn1)c2cccc(c2)C(=O)Nc3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H18 compound treatment 65040.0 -24300.0 -1.41 73680.0 -16400.0 -1.24 -1.8751 -0.998 1620067 TimTec1_006860 OC(=O)CSCC(=O)N(c1ccccc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H19 compound treatment 83400.0 -5970.0 -0.35 99880.0 9790.0 0.74 0.2794 0.3418 3212030 TimTec1_006861 CN(C)c1ccc(cc1)C(=O)N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H20 compound treatment 90840.0 1470.0 0.09 91200.0 1110.0 0.08 0.1196 1.0 1410666 TimTec1_006862 CC(C)N1CCN(CC1)C(=O)c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H21 compound treatment 86760.0 -2610.0 -0.15 84840.0 -5250.0 -0.4 -0.3879 -0.9121 3087568 TimTec1_006863 COC(=O)c1ccc(C(=O)OC)c2c(ccc(C(=O)OC)c12)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H22 compound treatment 74680.0 -14700.0 -0.85 84360.0 -5730.0 -0.43 -0.9085 -0.9512 1331832 TimTec1_006864 O=C(Cc1ccccc1)N2CCN(CCCc3ccccc3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H23 mock treatment 89720.0 354.0 0.02 94200.0 4110.0 0.31 0.2343 0.7521 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 H24 mock treatment 82880.0 -6490.0 -0.38 87200.0 -2890.0 -0.22 -0.4206 -0.967 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I01 compound treatment 49280.0 -40100.0 -2.32 69640.0 -20500.0 -1.55 -2.737 -0.9806 1174741 TimTec1_006865 Brc1ccc(cc1)C(=O)N(C2CCCCC2)c3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I02 compound treatment 64240.0 -25100.0 -1.46 101880.0 11800.0 0.89 -0.3985 -0.2334 3087571 TimTec1_006866 COC(=O)C(N)CSC1CCCCO1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I03 compound treatment 48800.0 -40600.0 -2.35 83760.0 -6330.0 -0.48 -2.0009 -0.8342 3212031 TimTec1_006867 COC(=O)c1ccccc1NC(=O)CSc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I04 compound treatment 63520.0 -25800.0 -1.5 101040.0 10900.0 0.83 -0.4729 -0.2763 1545093 TimTec1_006868 CCC(Sc1nc2ccccc2n1CC)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I05 compound treatment 39400.0 -50000.0 -2.89 65080.0 -25000.0 -1.89 -3.3858 -0.9788 1715211 TimTec1_006869 COc1ccc2[nH]c3c(=O)[nH]cnc3c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I06 compound treatment 29400.0 -60000.0 -3.47 46000.0 -44100.0 -3.34 -4.8167 -0.9998 3087574 TimTec1_006870 Cc1c(csc1c2ccccc2)C(=O)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I07 compound treatment 53200.0 -36200.0 -2.1 88880.0 -1210.0 -0.09 -1.5466 -0.7374 1913865 TimTec1_006871 c1c(nn(c1c2ccccc2)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I08 compound treatment 37400.0 -52000.0 -3.01 63760.0 -26300.0 -1.99 -3.5384 -0.9799 1606194 TimTec1_006872 CCOc1ccc(cc1)N(Cc2cccc3ccccc23)C(=O)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I09 compound treatment 41200.0 -48200.0 -2.79 56080.0 -34000.0 -2.57 -3.7938 -0.9992 1715376 TimTec1_006873 Cn1c(CC(O)c2cccc3ccccc23)nc4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I10 compound treatment 70760.0 -18600.0 -1.08 87360.0 -2730.0 -0.21 -0.9085 -0.8277 1788181 TimTec1_006874 CC(CN1CCCCC1)OC(=O)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I11 compound treatment 62760.0 -26600.0 -1.54 81960.0 -8130.0 -0.62 -1.5253 -0.9189 3212032 TimTec1_006875 CCc1ccc2[nH]c(=O)c(cc2c1)C(N3CCc4ccccc4C3)c5nnnn5C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I12 compound treatment 63400.0 -26000.0 -1.5 70680.0 -19400.0 -1.47 -2.1028 -0.9999 1156988 TimTec1_006876 CCc1nc2ccccc2c(C(=O)Nc3cccc(Cl)c3)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I13 compound treatment 32800.0 -56600.0 -3.28 37480.0 -52600.0 -3.98 -5.1335 -0.9953 1413757 TimTec1_006877 CCOc1ccccc1NC(=O)CSc2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I14 compound treatment 46920.0 -42400.0 -2.46 52680.0 -37400.0 -2.83 -3.7414 -0.9975 1330225 TimTec1_006878 CCCN(CCC)c1ncnc2ccc(Br)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I15 compound treatment 73920.0 -15400.0 -0.89 85360.0 -4730.0 -0.36 -0.8861 -0.9193 1340925 TimTec1_006879 C(N1CCNCC1)c2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I16 compound treatment 69120.0 -20200.0 -1.17 94640.0 4550.0 0.34 -0.5861 -0.4794 1241212 TimTec1_006880 CCN1CCc2c(C#N)c(N)sc2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I17 compound treatment 67880.0 -21500.0 -1.24 72120.0 -18000.0 -1.36 -1.8422 -0.999 1412589 TimTec1_006881 Nc1c(sc2nccc(Nc3ccccc3)c12)C(=O)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I18 compound treatment 39440.0 -49900.0 -2.89 43160.0 -46900.0 -3.55 -4.5574 -0.9948 3212033 TimTec1_006882 CCc1noc2CC(C/C(=N/O)/c12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I19 compound treatment 85920.0 -3450.0 -0.2 89560.0 -533.0 -0.04 -0.1697 -0.8331 1592654 TimTec1_006883 O=C(CCN1CCCCC1)NCC2OCCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I20 compound treatment 73440.0 -15900.0 -0.92 85200.0 -4890.0 -0.37 -0.9144 -0.9196 1513792 TimTec1_006884 O=c1oc2ccccc2n1Cn3c(=O)oc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I21 compound treatment 50320.0 -39000.0 -2.26 58880.0 -31200.0 -2.36 -3.2703 -0.9998 1204391 TimTec1_006885 COc1ccc(cc1)c2c(C)oc3ccc(Cl)cc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I22 compound treatment 90560.0 1190.0 0.07 92920.0 2830.0 0.21 0.2002 0.8903 1380204 TimTec1_006886 CCN(Cc1ccccc1)c2ccc(cc2)C3C4=C(CCCC4=O)Nc5[nH]c(=O)[nH]c(=O)c35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I23 mock treatment 88080.0 -1290.0 -0.07 92720.0 2630.0 0.2 0.0879 0.414 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 I24 mock treatment 96000.0 6630.0 0.38 89960.0 -133.0 -0.01 0.2647 0.6884 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J01 compound treatment 27040.0 -62300.0 -3.61 24680.0 -65400.0 -4.95 -6.0546 -0.988 3087584 TimTec1_006887 Clc1nc(Cl)nc(Nc2ccccc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J02 compound treatment 29480.0 -59900.0 -3.47 55040.0 -35100.0 -2.65 -4.3296 -0.9912 1255613 TimTec1_006888 CC1OC(C)C(C)C(O1)c2ccccc2O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J03 compound treatment 54040.0 -35300.0 -2.05 86480.0 -3610.0 -0.27 -1.6406 -0.7945 3212106 TimTec1_006889 CS(=O)(O)C1=C(O)C(=O)N(CCCC(=O)O)C1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J04 compound treatment 23920.0 -65400.0 -3.79 57840.0 -32300.0 -2.44 -4.4075 -0.9773 1787696 TimTec1_006890 CCCOc1cccc(NC(=O)c2occc2C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J05 compound treatment 61280.0 -28100.0 -1.63 76040.0 -14100.0 -1.06 -1.9028 -0.9788 1641308 TimTec1_006891 O=C(Cn1nnc(n1)c2ccccc2)N(c3ccccc3)c4ccc5ccccc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J06 compound treatment 55520.0 -33800.0 -1.96 74680.0 -15400.0 -1.17 -2.2116 -0.9692 1234881 TimTec1_006892 Nc1ncc(Cc2cccc(Cl)c2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J07 compound treatment 46920.0 -42400.0 -2.46 63760.0 -26300.0 -1.99 -3.1484 -0.9946 1553139 TimTec1_006893 O=S(=O)(N1CCOCC1)c2ccc3oc4ccccc4c3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J08 compound treatment 58560.0 -30800.0 -1.78 90960.0 867.0 0.07 -1.2157 -0.6806 1369411 TimTec1_006894 OC(COc1ccccc1Br)CN2CCNCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J09 compound treatment 53520.0 -35800.0 -2.08 59080.0 -31000.0 -2.35 -3.1285 -0.9981 3212107 TimTec1_006895 Cc1ccc(SCC(=O)NC(C)(C)C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J10 compound treatment 74480.0 -14900.0 -0.86 73960.0 -16100.0 -1.22 -1.4734 -0.9855 3087605 TimTec1_006896 NC(Cc1cccc2nsnc12)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J11 compound treatment 41280.0 -48100.0 -2.79 40120.0 -50000.0 -3.78 -4.6448 -0.9887 1081906 TimTec1_006897 Clc1ccc(OCc2ccccc2)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J12 compound treatment 62640.0 -26700.0 -1.55 59400.0 -30700.0 -2.32 -2.7377 -0.9806 1194697 TimTec1_006898 CC1(C)CC(=O)c2cc3c(N)c(sc3nc2C1)C(=O)c4ccc(Cl)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J13 compound treatment 74080.0 -15300.0 -0.89 72080.0 -18000.0 -1.36 -1.5904 -0.9782 1782465 TimTec1_006899 CNc1c(NC(=O)C)c(=O)oc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J14 compound treatment 66880.0 -22500.0 -1.3 71320.0 -18800.0 -1.42 -1.926 -0.9991 1212146 TimTec1_006900 O=C(COc1ccccc1)NCc2ccncc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J15 compound treatment 32080.0 -57300.0 -3.32 45960.0 -44100.0 -3.34 -4.7091 -1.0 1194336 TimTec1_006901 COc1ccc(Nc2nc3nonc3nc2N4CCCCCC4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J16 compound treatment 69880.0 -19500.0 -1.13 74160.0 -15900.0 -1.21 -1.6511 -0.9995 1574232 TimTec1_006902 CC1(C)CC(=O)C2=C(C1)Nc3ccccc3N(C2c4cccs4)C(=O)C5CC5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J17 compound treatment 55040.0 -34300.0 -1.99 74440.0 -15700.0 -1.18 -2.2441 -0.9694 1580883 TimTec1_006903 Nc1c(C#N)sc2nc(N3CCCCC3)c4CCCCc4c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J18 compound treatment 60760.0 -28600.0 -1.66 110560.0 20500.0 1.55 -0.0765 -0.0337 3212108 TimTec1_006904 CC(NC(=O)c1ccccc1)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J19 compound treatment 4640.0 -84700.0 -4.91 1440.0 -88700.0 -6.71 -8.2161 -0.9882 1166248 TimTec1_006905 CSc1ccc(CN2CCN(Cc3cccc(C)c3)CC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J20 compound treatment 73560.0 -15800.0 -0.92 80640.0 -9450.0 -0.72 -1.1535 -0.9926 3087610 TimTec1_006906 CCC(Cc1ccccc1)NC(=O)CC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J21 compound treatment 77080.0 -12300.0 -0.71 89360.0 -733.0 -0.06 -0.5426 -0.7599 1446397 TimTec1_006907 OC(=O)c1ccc2[nH]c3CCSCc3c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J22 compound treatment 88080.0 -1290.0 -0.07 80880.0 -9210.0 -0.7 -0.5458 -0.7782 1265101 TimTec1_006908 CC(CN1CCOCC1)OC(=O)C2COc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J23 mock treatment 83320.0 -6050.0 -0.35 87040.0 -3050.0 -0.23 -0.4111 -0.9796 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 J24 mock treatment 81560.0 -7810.0 -0.45 80360.0 -9730.0 -0.74 -0.8408 -0.9726 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K01 compound treatment 22680.0 -66700.0 -3.86 19360.0 -70700.0 -5.35 -6.5179 -0.9872 1298728 TimTec1_006909 Clc1ccc(OCC(=O)N(C2CCCCC2)c3ccccn3)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K02 compound treatment 52600.0 -36800.0 -2.13 69720.0 -20400.0 -1.54 -2.5967 -0.9874 1532077 TimTec1_006910 Cc1c(C)c2cc(ccc2n1Cc3ccccc3)C(=O)OCCN4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K03 compound treatment 16480.0 -72900.0 -4.22 39640.0 -50500.0 -3.82 -5.6865 -0.9987 1516458 TimTec1_006911 OC1(CCN(Cc2ccccc2)[C@@H]3CCCC[C@@H]31)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K04 compound treatment 47520.0 -41800.0 -2.42 74000.0 -16100.0 -1.22 -2.5757 -0.9493 1296444 TimTec1_006912 Fc1ccccc1C(=O)N2CCNCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K05 compound treatment 32480.0 -56900.0 -3.3 55280.0 -34800.0 -2.64 -4.1938 -0.9939 1669803 TimTec1_006913 CC(=O)Nc1ccc(cc1)C(C#N)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K06 compound treatment 11080.0 -78300.0 -4.54 24480.0 -65600.0 -4.97 -6.7191 -0.999 3212109 TimTec1_006914 CCC1CCCCN1C(=O)c2ccc(cc2)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K07 compound treatment 29520.0 -59800.0 -3.47 48120.0 -42000.0 -3.18 -4.6983 -0.999 1352014 TimTec1_006915 CCOc1ccc(CN2CCN(Cc3ccco3)CC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K08 compound treatment 34440.0 -54900.0 -3.18 45440.0 -44700.0 -3.38 -4.6402 -0.9995 1338673 TimTec1_006916 COc1ccc(CCNC(=O)c2ccccc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K09 compound treatment 7080.0 -82300.0 -4.77 8120.0 -82000.0 -6.2 -7.7586 -0.9915 1695069 TimTec1_006917 COc1ccc(cc1)c2csc(NCC=C)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K10 compound treatment 46120.0 -43200.0 -2.51 46880.0 -43200.0 -3.27 -4.0846 -0.9913 1788186 TimTec1_006918 CC(CN1CCOCC1)OC(=O)c2ccc3OCCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K11 compound treatment 59040.0 -30300.0 -1.76 58400.0 -31700.0 -2.4 -2.9387 -0.9883 3212110 TimTec1_006919 CCc1ccc2[nH]c(=O)c(cc2c1)C(N3CCN(CC3)C(=O)c4ccco4)c5nnnn5C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K12 compound treatment 48800.0 -40600.0 -2.35 48600.0 -41500.0 -3.14 -3.8828 -0.9898 1144082 TimTec1_006920 CCc1c(C)nc2ccc(OC)cc2c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K13 compound treatment 60400.0 -29000.0 -1.68 62440.0 -27700.0 -2.09 -2.6668 -0.994 1778845 TimTec1_006921 OC(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K14 compound treatment 15640.0 -73700.0 -4.27 17560.0 -72500.0 -5.49 -6.9027 -0.9923 3087618 TimTec1_006922 CCN(CC)c1scc([s+]1)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K15 compound treatment 63520.0 -25800.0 -1.5 67320.0 -22800.0 -1.72 -2.2778 -0.9975 1353321 TimTec1_006923 CCCOc1ccc(cc1)C(=O)N2CCCC2C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K16 compound treatment 64400.0 -25000.0 -1.45 69520.0 -20600.0 -1.56 -2.124 -0.9993 1042930 TimTec1_006924 CC(C)CCOc1ccc(cc1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K17 compound treatment 44080.0 -45300.0 -2.62 50200.0 -39900.0 -3.02 -3.9905 -0.9975 1312438 TimTec1_006925 CC(NC(=O)c1ccccc1)C2COc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K18 compound treatment 55760.0 -33600.0 -1.95 59200.0 -30900.0 -2.34 -3.0303 -0.9959 1382221 TimTec1_006926 CCOC(=O)c1[nH]c2ccccc2c1NC=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K19 compound treatment 43720.0 -45600.0 -2.64 48440.0 -41700.0 -3.15 -4.0995 -0.9962 1215729 TimTec1_006927 Cc1cc2c(o1)-c3c(CCC2(C)c4ccccc4)oc5ccccc35 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K20 compound treatment 54680.0 -34700.0 -2.01 60600.0 -29500.0 -2.23 -2.9996 -0.9986 1052507 TimTec1_006928 OC(CC(=O)Nc1ccccc1)(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K21 compound treatment 69840.0 -19500.0 -1.13 71960.0 -18100.0 -1.37 -1.7705 -0.9954 3087624 TimTec1_006929 COC(=O)CCCCC1=C(NC(=O)C)C(CS1)NC(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K22 compound treatment 59280.0 -30100.0 -1.74 59160.0 -30900.0 -2.34 -2.8882 -0.9894 3212111 TimTec1_006930 CC1CCN(CC1)C(=O)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K23 mock treatment 73120.0 -16200.0 -0.94 80040.0 -10100.0 -0.76 -1.2037 -0.9944 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 K24 mock treatment 81040.0 -8330.0 -0.48 73680.0 -16400.0 -1.24 -1.2196 -0.9151 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L01 compound treatment 70640.0 -18700.0 -1.08 84800.0 -5290.0 -0.4 -1.0505 -0.9083 1026720 TimTec1_006931 Cc1nc2ccc(cc2nc1C)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L02 compound treatment 1880.0 -87500.0 -5.07 2240.0 -87900.0 -6.65 -8.2864 -0.991 1370462 TimTec1_006932 CCc1ccc(CN2CCN(CC2)C(=O)c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L03 compound treatment 52880.0 -36500.0 -2.11 86240.0 -3850.0 -0.29 -1.701 -0.7971 3212112 TimTec1_006933 C(Cc1ccc2OCOc2c1)NCc3ccc4ccccc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L04 compound treatment 60760.0 -28600.0 -1.66 88440.0 -1650.0 -0.13 -1.2604 -0.7583 1152478 TimTec1_006934 COc1cc(cc(OC)c1OC)C(=O)N2CCNCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L05 compound treatment 37880.0 -51500.0 -2.98 68800.0 -21300.0 -1.61 -3.249 -0.9582 1921415 TimTec1_006935 O=C(C(c1ccccc1)c2ccccc2)N3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L06 compound treatment 58160.0 -31200.0 -1.81 85400.0 -4690.0 -0.36 -1.5296 -0.8302 1655667 TimTec1_006936 OC(=O)CCNC(=O)c1ccc2OCCOc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L07 compound treatment 11200.0 -78200.0 -4.53 17960.0 -72100.0 -5.46 -7.0632 -0.9957 1189724 TimTec1_006937 COc1ccc(cc1)C(=O)NC(C)Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L08 compound treatment 39040.0 -50300.0 -2.92 67680.0 -22400.0 -1.7 -3.2614 -0.9668 3212113 TimTec1_006938 COc1ccc(cc1)C2CC(=O)C=C(C2)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L09 compound treatment 79000.0 -10400.0 -0.6 77080.0 -13000.0 -0.99 -1.1212 -0.9718 3087630 TimTec1_006939 Brc1ccc(cc1)C(=O)COC(=O)Cc2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L10 compound treatment 18720.0 -70600.0 -4.09 21160.0 -68900.0 -5.22 -6.5838 -0.9928 3212114 TimTec1_006940 CC1CCN(C2CCCCC12)C(=O)c3cc4nc(cc(n4n3)C(F)(F)F)c5ccco5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L11 compound treatment 72040.0 -17300.0 -1.0 75040.0 -15100.0 -1.14 -1.5155 -0.998 3087632 TimTec1_006941 Nc1ccc(cc1)S(=O)(=O)CCC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L12 compound treatment 41600.0 -47800.0 -2.77 43160.0 -46900.0 -3.55 -4.4689 -0.9924 1238387 TimTec1_006942 COc1ccc2oc(C)c(C(O)c3cc4ccccc4o3)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L13 compound treatment 71040.0 -18300.0 -1.06 77000.0 -13100.0 -0.99 -1.4516 -0.9994 1613108 TimTec1_006943 OC1=C(C(N(CC=C)C1=O)c2ccccc2Cl)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L14 compound treatment 71040.0 -18300.0 -1.06 68040.0 -22100.0 -1.67 -1.9312 -0.9761 1237166 TimTec1_006944 Cc1ccc(cc1)C(N)(CC=C)CC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L15 compound treatment 79080.0 -10300.0 -0.6 84880.0 -5210.0 -0.39 -0.7004 -0.98 1169243 TimTec1_006945 CC1(C)CC(CCO1)NCc2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L16 compound treatment 54040.0 -35300.0 -2.05 52760.0 -37300.0 -2.83 -3.4455 -0.9875 3212188 TimTec1_006946 Cc1ccsc1/C=N/c2ccc(Nc3ccccc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L17 compound treatment 74640.0 -14700.0 -0.85 87000.0 -3090.0 -0.23 -0.7689 -0.869 1316960 TimTec1_006947 CC1(C)Cc2c(CO1)c(nc3sc(C#N)c(N)c23)N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L18 compound treatment 66000.0 -23400.0 -1.35 71960.0 -18100.0 -1.37 -1.9278 -1.0 1615665 TimTec1_006948 CCCCn1c(=O)c(C(=O)Nc2nccs2)c(O)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L19 compound treatment 21000.0 -68400.0 -3.96 53080.0 -37000.0 -2.8 -4.7819 -0.9856 1477509 TimTec1_006949 O=C(Oc1ccccc1)Oc2ccc3c(c2)oc(=O)c4ccccc43 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L20 compound treatment 82360.0 -7010.0 -0.41 93560.0 3470.0 0.26 -0.1015 -0.2099 1785312 TimTec1_006950 CCc1c(C(=O)O)c2ccccc2[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L21 compound treatment 51880.0 -37500.0 -2.17 68840.0 -21300.0 -1.61 -2.6733 -0.9891 1349942 TimTec1_006951 Cc1cccc(NC(=O)c2ccc(Br)o2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L22 compound treatment 82080.0 -7290.0 -0.42 81840.0 -8250.0 -0.62 -0.7402 -0.9818 1693483 TimTec1_006952 OC(=O)c1ccc(cc1)C2Nc3ccccc3C4C=CCC42 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L23 mock treatment 99160.0 9790.0 0.57 90520.0 427.0 0.03 0.4241 0.7462 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 L24 mock treatment 77160.0 -12200.0 -0.71 86880.0 -3210.0 -0.24 -0.672 -0.8986 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M01 compound treatment 77640.0 -11700.0 -0.68 80440.0 -9650.0 -0.73 -0.9971 -0.9993 3087638 TimTec1_006953 C[N+]1(CCC(=N1)N)c2cccc(c2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M02 compound treatment 60960.0 -28400.0 -1.65 74760.0 -15300.0 -1.16 -1.9844 -0.9854 1194545 TimTec1_006954 OC(=O)COc1cccc2nsnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M03 compound treatment 37720.0 -51600.0 -2.99 54120.0 -36000.0 -2.72 -4.0413 -0.9989 1448407 TimTec1_006955 CCOC(=O)C1=C(NC(=O)c2ccccc2)c3ccccc3CC41CCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M04 compound treatment 49560.0 -39800.0 -2.31 73760.0 -16300.0 -1.24 -2.505 -0.9573 1380989 TimTec1_006956 COC(=O)C1=C(C)NC2=C(C1c3cccc4ccccc34)C(=O)CC(C2)c5ccc(OC)cc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M05 compound treatment 54320.0 -35000.0 -2.03 75600.0 -14500.0 -1.1 -2.2115 -0.9582 1304492 TimTec1_006957 Fc1ccc(cc1)C(=O)CCCN2Cc3ccccc3C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M06 compound treatment 9440.0 -79900.0 -4.63 13960.0 -76100.0 -5.76 -7.3494 -0.9941 1290371 TimTec1_006958 CCCn1c2nc(C)c(C(=O)c3cccs3)n2c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M07 compound treatment 50920.0 -38400.0 -2.23 84800.0 -5290.0 -0.4 -1.8584 -0.8211 1210412 TimTec1_006959 Cc1ccc(NC(=O)c2c3CCCCc3nc4ccccc24)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M08 compound treatment 17320.0 -72000.0 -4.17 20920.0 -69200.0 -5.24 -6.654 -0.9937 1472306 TimTec1_006960 Cc1ccc2nc(NC(=O)c3ccccc3F)sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M09 compound treatment 49360.0 -40000.0 -2.32 52080.0 -38000.0 -2.88 -3.6736 -0.9943 3212189 TimTec1_006961 CCN(CC)c1ccc(C=C2C(=O)N(C)C(=O)N(C)C2=O)c(OCc3ccc(Cl)cc3Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M10 compound treatment 34720.0 -54600.0 -3.17 51680.0 -38400.0 -2.91 -4.2948 -0.9991 1788812 TimTec1_006962 CC1=Nc2ccccc2NC(=O)C1Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M11 compound treatment 63640.0 -25700.0 -1.49 72040.0 -18100.0 -1.37 -2.0202 -0.9991 1185528 TimTec1_006963 CCCOc1ccc(cc1OC)C(=O)N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M12 compound treatment 69840.0 -19500.0 -1.13 71640.0 -18500.0 -1.4 -1.7876 -0.9945 1123483 TimTec1_006964 CC(C)N1CCN(CC1)C(=O)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M13 compound treatment 51760.0 -37600.0 -2.18 63080.0 -27000.0 -2.04 -2.9865 -0.9995 3087674 TimTec1_006965 COc1ccc(CNc2ccccc2)cc1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M14 compound treatment 43160.0 -46200.0 -2.68 36680.0 -53400.0 -4.04 -4.7519 -0.98 3212190 TimTec1_006966 N1c2ccccc2[S+](c3ccccc3)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M15 compound treatment 66960.0 -22400.0 -1.3 54840.0 -35300.0 -2.67 -2.8048 -0.9452 1703037 TimTec1_006967 CCOC(=O)c1ccc(NC(=O)C2C3CCCCC23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M16 compound treatment 72960.0 -16400.0 -0.95 70120.0 -20000.0 -1.51 -1.7412 -0.975 1401277 TimTec1_006968 O=C(N1CCn2c1nc3ccccc23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M17 compound treatment 46400.0 -43000.0 -2.49 49960.0 -40100.0 -3.04 -3.9083 -0.9951 3087677 TimTec1_006969 CCn1c(nc2ccccc12)c3ccc(OC)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M18 compound treatment 75440.0 -13900.0 -0.81 79280.0 -10800.0 -0.82 -1.1493 -1.0 3087679 TimTec1_006970 CC1=CC(C)(C)NC(=O)N1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M19 compound treatment 47280.0 -42100.0 -2.44 54520.0 -35600.0 -2.69 -3.6282 -0.9988 1777670 TimTec1_006971 COc1ccc(/C=C/C2=CCN(Cc3ccccc3)CC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M20 compound treatment 81200.0 -8170.0 -0.47 82120.0 -7970.0 -0.6 -0.7613 -0.9927 3212191 TimTec1_006972 FC(F)(F)c1c2CCc3ccccc3-c2nc4cc(nn14)C(=O)NCc5ccco5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M21 compound treatment 72360.0 -17000.0 -0.99 82760.0 -7330.0 -0.56 -1.0892 -0.9631 1654108 TimTec1_006973 Sc1nnc([nH]1)C2COc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M22 compound treatment 78720.0 -10600.0 -0.62 75920.0 -14200.0 -1.07 -1.1947 -0.9655 3212192 TimTec1_006974 O/N=C\1/CCCc2nn(nc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M23 mock treatment 81520.0 -7850.0 -0.45 95640.0 5550.0 0.42 -0.0245 -0.0397 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 M24 mock treatment 91480.0 2110.0 0.12 82360.0 -7730.0 -0.59 -0.3273 -0.5473 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N01 compound treatment 46600.0 -42800.0 -2.48 74840.0 -15300.0 -1.15 -2.5684 -0.9396 1462528 TimTec1_006975 CCOC(=O)c1c(NC(=O)c2cc3ccccc3o2)sc4COC(C)(C)Cc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N02 compound treatment 17360.0 -72000.0 -4.17 30680.0 -59400.0 -4.5 -6.13 -0.9993 1444731 TimTec1_006976 COc1ccc2nc(nc(N3CCCCC3)c2c1)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N03 compound treatment 38560.0 -50800.0 -2.94 62520.0 -27600.0 -2.09 -3.5572 -0.9858 3212193 TimTec1_006977 NC(=O)CSc1ncnc2sc3CCCCc3c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N04 compound treatment 20040.0 -69300.0 -4.02 28840.0 -61300.0 -4.64 -6.1187 -0.9974 3087684 TimTec1_006978 COC(=O)c1ccc(Nc2nc(c(C)s2)c3ccc(Br)cc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N05 compound treatment 26160.0 -63200.0 -3.66 42400.0 -47700.0 -3.61 -5.1422 -1.0 3212194 TimTec1_006979 CC(C)(C)c1ccc(cc1)c2nnnn2c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N06 compound treatment 48720.0 -40600.0 -2.35 77800.0 -12300.0 -0.93 -2.3232 -0.9175 1782862 TimTec1_006980 O=C(CCNc1n[nH]c(=O)[nH]c1=O)N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N07 compound treatment 46640.0 -42700.0 -2.48 74560.0 -15500.0 -1.18 -2.5818 -0.9421 1650008 TimTec1_006981 Cc1cccc(Nc2cc(=O)[nH]c(=O)[nH]2)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N08 compound treatment 49080.0 -40300.0 -2.33 73920.0 -16200.0 -1.22 -2.5161 -0.9546 1497501 TimTec1_006982 CC1CCN(CCC(=O)Nc2ccccc2F)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N09 compound treatment 50680.0 -38700.0 -2.24 60240.0 -29900.0 -2.26 -3.1828 -1.0 1669677 TimTec1_006983 CCOC(=O)c1c(NC(=S)NCC(=C)C)scc1c2ccsc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N10 compound treatment 56560.0 -32800.0 -1.9 56760.0 -33300.0 -2.52 -3.1281 -0.9902 3212195 TimTec1_006984 Oc1ccccc1C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N11 compound treatment 54720.0 -34600.0 -2.01 51480.0 -38600.0 -2.92 -3.4861 -0.9832 1273018 TimTec1_006985 CC1=CC(C)(C)c2ccccc2N1Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N12 compound treatment 46720.0 -42600.0 -2.47 52680.0 -37400.0 -2.83 -3.7496 -0.9977 3212196 TimTec1_006986 CCc1c(C)nc2ccc(C)cc2c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N13 compound treatment 63600.0 -25800.0 -1.49 67400.0 -22700.0 -1.72 -2.2702 -0.9976 1280587 TimTec1_006987 C(NC1CCCCC1)C2OCc3ccccc3CO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N14 compound treatment 78480.0 -10900.0 -0.63 66800.0 -23300.0 -1.76 -1.6927 -0.904 1270926 TimTec1_006988 OC(=O)CCC(=O)Nc1ccc(Oc2ccc(Cl)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N15 compound treatment 66080.0 -23300.0 -1.35 61360.0 -28700.0 -2.17 -2.4919 -0.9736 1479468 TimTec1_006989 O=C(NC(c1ccccc1)c2ccccc2)c3ccc4OCCOc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N16 compound treatment 69600.0 -19800.0 -1.15 76320.0 -13800.0 -1.04 -1.547 -0.9989 1290955 TimTec1_006990 OCCN(CCO)C(=O)COc1ccc(Br)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N17 compound treatment 65120.0 -24200.0 -1.4 65040.0 -25100.0 -1.9 -2.3343 -0.9891 3212197 TimTec1_006991 CC(C)(C)c1ccc(OCc2nnc(SCC(=O)N)n2c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N18 compound treatment 68280.0 -21100.0 -1.22 78920.0 -11200.0 -0.85 -1.4619 -0.9839 1452106 TimTec1_006992 CCC(=O)NC(c1ccc(cc1)C(C)C)c2c(O)ccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N19 compound treatment 77600.0 -11800.0 -0.68 69440.0 -20700.0 -1.56 -1.5875 -0.9308 1151230 TimTec1_006993 CC1(CN(Cc2ccccc2)CC3(C)CN(Cc4ccccc4)C1)C3=NO 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N20 compound treatment 1000.0 -88400.0 -5.12 920.0 -89200.0 -6.75 -8.3931 -0.9907 3087690 TimTec1_006994 NC(=O)c/1cc2ccccc2o\c1=N/O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N21 compound treatment 72960.0 -16400.0 -0.95 72240.0 -17900.0 -1.35 -1.6277 -0.9852 1301823 TimTec1_006995 OC(=O)CCS(=O)(=O)c1ccc(Br)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N22 compound treatment 39760.0 -49600.0 -2.87 37600.0 -52500.0 -3.97 -4.8419 -0.9874 1570261 TimTec1_006996 CN(C)S(=O)(=O)Nc1ccc(cc1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N23 mock treatment 82280.0 -7090.0 -0.41 79600.0 -10500.0 -0.79 -0.8519 -0.9528 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 N24 mock treatment 87720.0 -1650.0 -0.1 76480.0 -13600.0 -1.03 -0.7961 -0.7693 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O01 compound treatment 42080.0 -47300.0 -2.74 56200.0 -33900.0 -2.57 -3.7513 -0.9995 1350651 TimTec1_006997 COc1cccc(CC(Cc2nc3ccccc3[nH]2)c4nc5ccccc5[nH]4)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O02 compound treatment 77280.0 -12100.0 -0.7 98320.0 8230.0 0.62 -0.0548 -0.0585 1318205 TimTec1_006998 Cc1ccc(Cc2cnc(NC(=O)C(c3ccccc3)c4ccccc4)s2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O03 compound treatment 42240.0 -47100.0 -2.73 61200.0 -28900.0 -2.19 -3.4771 -0.994 1553933 TimTec1_006999 Cc1cc(SCC(=O)N2CCCCC2)nc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O04 compound treatment 63280.0 -26100.0 -1.51 85920.0 -4170.0 -0.32 -1.2921 -0.8368 1159118 TimTec1_007000 Cc1cc(C(=O)O)c2cc(F)ccc2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O05 compound treatment 65880.0 -23500.0 -1.36 77560.0 -12500.0 -0.95 -1.633 -0.9845 1599562 TimTec1_007001 C(CN1CCNCC1)Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O06 compound treatment 59320.0 -30000.0 -1.74 94840.0 4750.0 0.36 -0.9769 -0.5496 3087694 TimTec1_007002 CC1CC(n2nc(cc2N1)C(=O)O)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O07 compound treatment 59520.0 -29800.0 -1.73 76000.0 -14100.0 -1.07 -1.9771 -0.9731 1578115 TimTec1_007003 C(N1CCN(Cc2ccncc2)CC1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O08 compound treatment 61040.0 -28300.0 -1.64 80160.0 -9930.0 -0.75 -1.6921 -0.9374 1918993 TimTec1_007004 Oc1ccc(O)c(c1)[S+]2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O09 compound treatment 4600.0 -84800.0 -4.91 4240.0 -85900.0 -6.5 -8.0679 -0.9905 3212273 TimTec1_007005 O=C1NC(=C(C#N)C2(CCCC2)C1C#N)SCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O10 compound treatment 49600.0 -39800.0 -2.3 46640.0 -43500.0 -3.29 -3.9549 -0.9848 1427630 TimTec1_007006 Clc1ccc(OCc2cn3ccccc3n2)c4ncccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O11 compound treatment 68520.0 -20800.0 -1.21 67400.0 -22700.0 -1.72 -2.0686 -0.9851 1738341 TimTec1_007007 O=C(NCc1ccccc1)C2C3CCCCC23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O12 compound treatment 81840.0 -7530.0 -0.44 76920.0 -13200.0 -1.0 -1.0134 -0.9312 1437987 TimTec1_007008 COc1ccc(cc1)C(=O)NC(CC(C)C)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O13 compound treatment 24200.0 -65200.0 -3.78 24360.0 -65700.0 -4.98 -6.188 -0.9907 3212274 TimTec1_007009 COc1ccc(Nc2nc(cs2)c3cccs3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O14 compound treatment 82920.0 -6450.0 -0.37 89560.0 -533.0 -0.04 -0.2926 -0.7789 1279048 TimTec1_007010 Cc1ccc(NC(=O)CCN2CCCCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O15 compound treatment 80560.0 -8810.0 -0.51 85160.0 -4930.0 -0.37 -0.6248 -0.9882 1265764 TimTec1_007011 COc1cc(OC)c(OC)cc1CN2CCN(CC2)C(=O)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O16 compound treatment 38760.0 -50600.0 -2.93 36640.0 -53500.0 -4.05 -4.9343 -0.9875 3087714 TimTec1_007012 CNc1nc(cc(n1)c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O17 compound treatment 40080.0 -49300.0 -2.86 39360.0 -50700.0 -3.84 -4.7346 -0.9894 1652569 TimTec1_007013 C=C1C(C1C(=O)Nc2ccc3OCCOc3c2)C(=O)Nc4ccc5OCCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O18 compound treatment 93000.0 3630.0 0.21 84840.0 -5250.0 -0.4 -0.1323 -0.294 3086771 TimTec1_007014 CCN(CC)CCn1cnc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O19 compound treatment 4320.0 -85000.0 -4.93 3880.0 -86200.0 -6.53 -8.0986 -0.9904 1705111 TimTec1_007015 COc1cccc(NC(=O)c2cc3ccccc3oc2=O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O20 compound treatment 83600.0 -5770.0 -0.33 87880.0 -2210.0 -0.17 -0.3547 -0.949 3212275 TimTec1_007016 OC(=O)c1ccccc1NS(=O)(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O21 compound treatment 85480.0 -3890.0 -0.23 90560.0 467.0 0.04 -0.1342 -0.5889 1788989 TimTec1_007017 CCOC(=O)c1c(C)nc2ccccc2c1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O22 compound treatment 8280.0 -81100.0 -4.7 7360.0 -82700.0 -6.26 -7.7501 -0.99 1226950 TimTec1_007018 CC(C)c1ccc2oc(nc2c1)c3ccc(N)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O23 mock treatment 97400.0 8030.0 0.47 88040.0 -2050.0 -0.16 0.2192 0.4468 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 O24 mock treatment 101760.0 12400.0 0.72 88680.0 -1410.0 -0.11 0.4321 0.5952 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P01 compound treatment 48440.0 -40900.0 -2.37 76040.0 -14100.0 -1.06 -2.4288 -0.9346 3086772 TimTec1_007019 Cc1ccc(NCCNc2ccc(C)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P02 compound treatment 43000.0 -46400.0 -2.69 55760.0 -34300.0 -2.6 -3.7372 -0.9999 1505666 TimTec1_007020 Cc1sc(NC(=O)c2ccccc2F)c(C(=O)c3ccc(Cl)cc3)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P03 compound treatment 46800.0 -42600.0 -2.47 68720.0 -21400.0 -1.62 -2.8878 -0.9791 3212276 TimTec1_007021 CC(C)c1ccc(NC(=O)c2cc3NC(CC(n3n2)C(F)(F)F)c4ccco4)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P04 compound treatment 47000.0 -42400.0 -2.45 59520.0 -30600.0 -2.31 -3.3721 -0.9996 1372504 TimTec1_007022 Nc1ccccc1SCC(=O)N2CCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P05 compound treatment 57360.0 -32000.0 -1.85 65200.0 -24900.0 -1.88 -2.6436 -1.0 1334056 TimTec1_007023 CC(=O)Nc1cc2OCCOc2cc1N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P06 compound treatment 39760.0 -49600.0 -2.87 50920.0 -39200.0 -2.97 -4.129 -0.9999 1286842 TimTec1_007024 CC(C(=O)Nc1cccc(C)c1)C(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P07 compound treatment 28480.0 -60900.0 -3.53 34800.0 -55300.0 -4.19 -5.4539 -0.9964 1511538 TimTec1_007025 Cc1cc(nc(n1)c2ccc(Br)cc2)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P08 compound treatment 27400.0 -62000.0 -3.59 40040.0 -50100.0 -3.79 -5.2177 -0.9996 3212277 TimTec1_007026 CCCC/C(=N\O)/c1c(C)[nH]c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P09 compound treatment 66120.0 -23200.0 -1.35 40000.0 -50100.0 -3.79 -3.6335 -0.903 1544658 TimTec1_007027 O=c1oc2ccccc2cc1c3csc(n3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P10 compound treatment 40080.0 -49300.0 -2.86 32840.0 -57300.0 -4.33 -5.0836 -0.9795 1397424 TimTec1_007028 Cc1ccc2cc(C)c(NCc3cccnc3)nc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P11 compound treatment 61080.0 -28300.0 -1.64 67800.0 -22300.0 -1.69 -2.352 -0.9999 3212278 TimTec1_007029 Cc1nc(nc(O)c1CC=C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P12 compound treatment 63520.0 -25800.0 -1.5 65720.0 -24400.0 -1.84 -2.3634 -0.9946 3086773 TimTec1_007030 CC1(C)CC(=O)C=C(C1)NN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P13 compound treatment 28760.0 -60600.0 -3.51 30680.0 -59400.0 -4.5 -5.6629 -0.9925 1421894 TimTec1_007031 Cc1ccc(O)c(c1)c2cc([nH]n2)c3ccc(cc3)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P14 compound treatment 53320.0 -36000.0 -2.09 48080.0 -42000.0 -3.18 -3.7254 -0.9792 1581406 TimTec1_007032 Cc1ccccc1OCC(=O)Nc2cccc(c2)N3C(=O)c4ccccc4C3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P15 compound treatment 51200.0 -38200.0 -2.21 54480.0 -35600.0 -2.7 -3.4697 -0.9952 3086774 TimTec1_007033 O=S(=O)(Nc1ccc2ccccc2c1)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P16 compound treatment 68920.0 -20400.0 -1.18 78480.0 -11600.0 -0.88 -1.4592 -0.9892 3212279 TimTec1_007034 OC(=O)CCCNC1=NC(=O)CC(=O)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P17 compound treatment 64960.0 -24400.0 -1.41 74120.0 -16000.0 -1.21 -1.8548 -0.997 1305963 TimTec1_007035 Cc1ccc(cc1S(=O)(=O)N)c2nnc(Nc3ccc(cc3)S(=O)(=O)N)c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P18 compound treatment 66240.0 -23100.0 -1.34 63040.0 -27100.0 -2.05 -2.3954 -0.9789 3086775 TimTec1_007036 CCN(CC)C(=O)C1CC(=O)OC1(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P19 compound treatment 74520.0 -14800.0 -0.86 79080.0 -11000.0 -0.83 -1.1977 -0.9999 1786463 TimTec1_007037 CC1(C)CC2(CCCN(CCCN3CCCC4(CCOC(C)(C)C4)C3)C2)CCO1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P20 compound treatment 73480.0 -15900.0 -0.92 68880.0 -21200.0 -1.61 -1.7862 -0.9651 1468821 TimTec1_007038 O=C(OCC1CCCN2CCCCC12)c3ccc4OCOc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P21 compound treatment 71400.0 -18000.0 -1.04 74480.0 -15600.0 -1.18 -1.5717 -0.998 1531258 TimTec1_007039 CCNC(=S)Nc1c(C)n(C)n(c2ccccc2)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P22 compound treatment 75800.0 -13600.0 -0.79 56480.0 -33600.0 -2.54 -2.3549 -0.8843 1580338 TimTec1_007040 CC(=O)N(CC(=O)Nc1ccc(C)cc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P23 mock treatment 77560.0 -11800.0 -0.68 68200.0 -21900.0 -1.66 -1.6555 -0.9234 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2082 P24 mock treatment 78280.0 -11100.0 -0.64 76280.0 -13800.0 -1.05 -1.1935 -0.9726 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A01 compound treatment 96280.0 12400.0 0.72 88280.0 14600.0 1.11 1.2906 0.9778 1553711 TimTec1_007041 CC(=O)N1CCN(CC1)c2ccc(N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A02 compound treatment 91360.0 7460.0 0.43 74120.0 480.0 0.04 0.3311 0.7639 3212280 TimTec1_007042 Cc1ccc(cc1)C(=O)N2CCC(CC2)C(=O)NC3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A03 compound treatment 29040.0 -54900.0 -3.18 20280.0 -53400.0 -4.04 -5.1037 -0.993 3212281 TimTec1_007043 O=C(CSc1ncnc2sc3CCCCc3c12)N4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A04 compound treatment 78880.0 -5020.0 -0.29 53960.0 -19700.0 -1.49 -1.2592 -0.8296 1162667 TimTec1_007044 CCOC(=O)CSC1=C(C#N)C(CC(=O)N1)c2cccc(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A05 compound treatment 47480.0 -36400.0 -2.11 40200.0 -33400.0 -2.53 -3.2821 -0.9959 3212282 TimTec1_007045 Nc1ccc(cc1Cl)c2nc3ccc(N)c(Cl)c3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A06 compound treatment 49800.0 -34100.0 -1.98 46120.0 -27500.0 -2.08 -2.8702 -0.9997 1490444 TimTec1_007046 CC(=O)Nc1ccc(cc1)c2nc3ccccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A07 compound treatment 112960.0 29100.0 1.68 90080.0 16400.0 1.24 2.0703 0.9889 1550978 TimTec1_007047 CCOC(=O)c1c(NC(=O)COC(=O)c2cn(CC)c3nc(C)ccc3c2=O)sc4CCCCc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A08 compound treatment 89800.0 5900.0 0.34 77080.0 3440.0 0.26 0.4256 0.991 1241536 TimTec1_007048 Cc1c(C)c2ccc(OCC(=O)N)cc2oc1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A09 compound treatment 99160.0 15300.0 0.88 75360.0 1720.0 0.13 0.717 0.8026 1694138 TimTec1_007049 Nc1ccc(NC(=O)CCN2CCOCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A10 compound treatment 12720.0 -71200.0 -4.12 12680.0 -61000.0 -4.61 -6.1791 -0.9984 1593211 TimTec1_007050 Nn1c(Nc2ccccc2)nc3sc4CCCc4c3c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A11 compound treatment 90440.0 6540.0 0.38 78560.0 4920.0 0.37 0.5311 1.0 1077423 TimTec1_007051 CC(c1ccccc1)n2cncc2C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A12 compound treatment 88320.0 4420.0 0.26 73680.0 40.0 0.0 0.183 0.7154 3212283 TimTec1_007052 Cn1c(nc2ccccc12)c3nonc3NC(=O)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A13 compound treatment 89560.0 5660.0 0.33 77520.0 3880.0 0.29 0.4394 0.9985 3086776 TimTec1_007053 CN(C(=O)C)c1nc(N)n(n1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A14 compound treatment 89600.0 5700.0 0.33 73440.0 -200.0 -0.02 0.2226 0.674 1377163 TimTec1_007054 COc1ccc(CCNC2(Cc3ccccc3)CC(C)N(C)CC2C)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A15 compound treatment 81800.0 -2100.0 -0.12 69080.0 -4560.0 -0.35 -0.3303 -0.9023 3086777 TimTec1_007055 CCCSc1ncnc2sc3CCCCc3c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A16 compound treatment 81840.0 -2060.0 -0.12 87840.0 14200.0 1.07 0.6755 0.6246 1617565 TimTec1_007056 O=C(Oc1ccccn1)C2COc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A17 compound treatment 90080.0 6180.0 0.36 72160.0 -1480.0 -0.11 0.1738 0.4635 1378399 TimTec1_007057 CC(C)Oc1ccccc1C(=O)NC(CO)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A18 compound treatment 61760.0 -22100.0 -1.28 55200.0 -18400.0 -1.4 -1.8942 -0.9991 1498887 TimTec1_007058 Cc1ccc(cc1)C(=O)CNc2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A19 compound treatment 92560.0 8660.0 0.5 65280.0 -8360.0 -0.63 -0.0929 -0.115 3086778 TimTec1_007059 CCC(C)(C)C(=O)Nc1nnc(s1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A20 compound treatment 90000.0 6100.0 0.35 77440.0 3800.0 0.29 0.4531 0.9948 1197829 TimTec1_007060 OC(=O)CCC(=O)Nc1cc(Cl)ccc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A21 compound treatment 74840.0 -9060.0 -0.53 65880.0 -7760.0 -0.59 -0.7867 -0.9984 1218361 TimTec1_007061 CC(C)(C)c1cn2c(nc3ccccc32)n1CCN4CCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A22 compound treatment 74320.0 -9580.0 -0.56 66880.0 -6760.0 -0.51 -0.7545 -0.9992 3086779 TimTec1_007062 CCOc1ccc(cc1)C2C(=CN(CCOC)C=C2C(=O)OC)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A23 mock treatment 98400.0 14500.0 0.84 82520.0 8880.0 0.67 1.0691 0.9939 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 A24 mock treatment 113400.0 29500.0 1.71 91760.0 18100.0 1.37 2.1782 0.9941 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B01 compound treatment 108080.0 24200.0 1.4 86840.0 13200.0 1.0 1.6969 0.9863 3212284 TimTec1_007063 O=C(NCCNC1=NS(=O)(=O)c2ccccc12)c3ccncc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B02 compound treatment 102440.0 18500.0 1.07 85200.0 11600.0 0.88 1.3781 0.9948 1124094 TimTec1_007064 CC1CCN(CC1)C(=O)C2C(C3CC2C=C3)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B03 compound treatment 28000.0 -55900.0 -3.24 24520.0 -49100.0 -3.72 -4.9194 -0.9976 1411725 TimTec1_007065 Nc1ccc(cc1)c2cn3ccccc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B04 compound treatment 101920.0 18000.0 1.04 81880.0 8240.0 0.62 1.1791 0.9697 1787257 TimTec1_007066 Cn1c(=O)[nH]c(=O)c2n(CCN3CCOCC3)cnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B05 compound treatment 73480.0 -10400.0 -0.6 64160.0 -9480.0 -0.72 -0.9345 -0.9963 1500476 TimTec1_007067 COC1CCCCC1Nc2cc(C)ccc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B06 compound treatment 97800.0 13900.0 0.81 78320.0 4680.0 0.35 0.8198 0.932 3212358 TimTec1_007068 COC(=O)COc1ccc2ccccc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B07 compound treatment 78320.0 -5580.0 -0.32 56440.0 -17200.0 -1.3 -1.1494 -0.8568 3086780 TimTec1_007069 Cc1ccc(NCC2COc3ccccc3O2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B08 compound treatment 86000.0 2100.0 0.12 68880.0 -4760.0 -0.36 -0.1689 -0.4443 3212359 TimTec1_007070 FC(F)(F)C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B09 compound treatment 89040.0 5140.0 0.3 69480.0 -4160.0 -0.31 -0.0123 -0.0283 3086781 TimTec1_007071 S=c1n(CCC#N)c2ccccc2n1CCC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B10 compound treatment 87000.0 3100.0 0.18 69320.0 -4320.0 -0.33 -0.1044 -0.2799 1615066 TimTec1_007072 Cc1cc(nc(n1)N2CCOCC2)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B11 compound treatment 94600.0 10700.0 0.62 84120.0 10500.0 0.79 0.9991 0.9925 1329642 TimTec1_007073 OC(C(O)C(=O)Nc1ccccc1)C(=O)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B12 compound treatment 95240.0 11300.0 0.66 75880.0 2240.0 0.17 0.5843 0.8614 3086783 TimTec1_007074 COc1ccc(cc1)N(C(C(=O)NC2CCCCC2)c3ccc(C)o3)C(=O)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B13 compound treatment 69120.0 -14800.0 -0.86 61200.0 -12400.0 -0.94 -1.2715 -0.9989 1156856 TimTec1_007075 COc1ccc(Cl)cc1NC(=O)CN(C2CCCCC2)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B14 compound treatment 99080.0 15200.0 0.88 79360.0 5720.0 0.43 0.9279 0.9467 3086785 TimTec1_007076 Cc1cc(N)n(n1)C2CCOC(C)(C)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B15 compound treatment 73480.0 -10400.0 -0.6 65800.0 -7840.0 -0.59 -0.8467 -1.0 3212360 TimTec1_007077 CN1CCCC(C1)OC(=O)C(C)(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B16 compound treatment 30680.0 -53200.0 -3.08 30960.0 -42700.0 -3.23 -4.4649 -0.9997 1215637 TimTec1_007078 Nc1ccc(CCc2nc3ccccc3o2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B17 compound treatment 87760.0 3860.0 0.22 82360.0 8720.0 0.66 0.6247 0.8965 1249972 TimTec1_007079 CN(C)Cc1c(O)ccc2c(C)cc(=O)oc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B18 compound treatment 84000.0 95.5 0.01 81240.0 7600.0 0.58 0.4107 0.7139 1386364 TimTec1_007080 CCn1ccnc1C(O)c2ccc(OC)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B19 compound treatment 88840.0 4940.0 0.29 81920.0 8280.0 0.63 0.6454 0.9368 3086788 TimTec1_007081 CCSc1nsc(SCC)c1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B20 compound treatment 72360.0 -11500.0 -0.67 62760.0 -10900.0 -0.82 -1.0553 -0.9947 3212361 TimTec1_007082 Cc1cc(NC(=O)c2sc(Nc3cccc(c3)C(F)(F)F)nc2N)no1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B21 compound treatment 86080.0 2180.0 0.13 74760.0 1120.0 0.08 0.1491 0.9814 3086790 TimTec1_007083 CN/1CCC\C1=N/c2ccccc2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B22 compound treatment 84840.0 935.0 0.05 73080.0 -560.0 -0.04 0.0084 0.1214 1642345 TimTec1_007084 CCCn1c(=O)c(C(=O)NCc2ccccc2)c(O)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B23 mock treatment 97120.0 13200.0 0.77 94280.0 20600.0 1.56 1.6461 0.9461 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 B24 mock treatment 106320.0 22400.0 1.3 85600.0 12000.0 0.91 1.5585 0.9844 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C01 compound treatment 105120.0 21200.0 1.23 77160.0 3520.0 0.27 1.0576 0.8409 3086791 TimTec1_007085 O=C(C(Cc1ccccc1)N2C(=O)C3C4CC(C=C4)C3C2=O)N5CCOCC5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C02 compound treatment 51960.0 -31900.0 -1.85 48800.0 -24800.0 -1.88 -2.6382 -1.0 3212362 TimTec1_007086 COc1ccc(cc1)N2C(=O)CC2(/C=C/c3ccccc3)C(=O)NC4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C03 compound treatment 72440.0 -11500.0 -0.66 53800.0 -19800.0 -1.5 -1.5316 -0.9327 3086839 TimTec1_007087 O=C(CSc1ncnc2sc3CCCCc3c12)OC4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C04 compound treatment 100520.0 16600.0 0.96 91360.0 17700.0 1.34 1.6292 0.9868 1133272 TimTec1_007088 O=C(NCC1CCCO1)C2CCN(CC3CCCCC3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C05 compound treatment 4720.0 -79200.0 -4.59 6320.0 -67300.0 -5.1 -6.8473 -0.9986 1372624 TimTec1_007089 CCN(CC)c1nc(nc2ccccc12)c3ccncc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C06 compound treatment 71760.0 -12100.0 -0.7 60240.0 -13400.0 -1.01 -1.2148 -0.984 1360767 TimTec1_007090 CCC(=O)Nc1sc2CCCCc2c1C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C07 compound treatment 50680.0 -33200.0 -1.92 39720.0 -33900.0 -2.57 -3.1767 -0.9899 3212363 TimTec1_007091 CCOC(=O)c1sc(NC(=O)C(CC)OC(=O)c2c3CCCc3nc4ccccc24)nc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C08 compound treatment 73400.0 -10500.0 -0.61 54440.0 -19200.0 -1.45 -1.458 -0.9254 3086844 TimTec1_007092 Clc1ccc2oc(=O)c(cc2c1)c3nc4ccccc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C09 compound treatment 93240.0 9340.0 0.54 71680.0 -1960.0 -0.15 0.2776 0.4949 3212364 TimTec1_007093 OC(=O)C1Cc2[nH]cnc2C(N1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C10 compound treatment 89320.0 5420.0 0.31 75800.0 2160.0 0.16 0.3375 0.9538 3086846 TimTec1_007094 Cc1cc(C)n(CCSCC(=O)O)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C11 compound treatment 85880.0 1980.0 0.11 73200.0 -440.0 -0.03 0.0574 0.4814 1326461 TimTec1_007095 O=C(COc1ccc2ccccc2c1)NCc3ccc4OCOc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C12 compound treatment 40800.0 -43100.0 -2.5 39040.0 -34600.0 -2.62 -3.6178 -0.9997 3086847 TimTec1_007096 Cc1csc(NC(=O)c2ccccc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C13 compound treatment 82680.0 -1220.0 -0.07 68000.0 -5640.0 -0.43 -0.352 -0.8135 1250239 TimTec1_007097 Brc1cc(Br)c2oc(=O)c(cc2c1)C(=O)N3CCCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C14 compound treatment 77200.0 -6700.0 -0.39 68720.0 -4920.0 -0.37 -0.538 -0.9998 3212365 TimTec1_007098 COc1cc(SC)ccc1C(=O)Nc2nnc(s2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C15 compound treatment 80360.0 -3540.0 -0.21 70520.0 -3120.0 -0.24 -0.3122 -0.9976 1524512 TimTec1_007099 Nc1ccc2[nH]c(nc2c1)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C16 compound treatment 86320.0 2420.0 0.14 78720.0 5080.0 0.38 0.3709 0.9063 1424180 TimTec1_007100 OC(=O)c1ccc(NC(=O)C2CC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C17 compound treatment 31800.0 -52100.0 -3.02 34040.0 -39600.0 -3.0 -4.2542 -1.0 1263746 TimTec1_007101 Oc1c2CCCc2nc3cc(nn13)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C18 compound treatment 84120.0 215.0 0.01 76360.0 2720.0 0.21 0.1544 0.7486 1917903 TimTec1_007102 OC(=O)c1sc2cc(F)ccc2c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C19 compound treatment 59280.0 -24600.0 -1.43 64040.0 -9600.0 -0.73 -1.5227 -0.951 1724549 TimTec1_007103 Clc1ccc(OCC(=O)Nc2cccc(Cl)c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C20 compound treatment 84160.0 255.0 0.01 71480.0 -2160.0 -0.16 -0.1051 -0.6405 1611210 TimTec1_007104 COc1cccc(C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C21 compound treatment 84760.0 855.0 0.05 74040.0 400.0 0.03 0.0565 0.972 1785828 TimTec1_007105 CCOC(=O)c1c(O)c2CCCCc2[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C22 compound treatment 82520.0 -1380.0 -0.08 74560.0 920.0 0.07 -0.0075 -0.0704 3212366 TimTec1_007106 COc1ccc(cc1OC)C(N(C(=O)c2cc[nH]n2)c3ccc(F)cc3)C(=O)NC4CCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C23 mock treatment 90360.0 6460.0 0.37 83560.0 9920.0 0.75 0.7954 0.9482 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 C24 mock treatment 90760.0 6860.0 0.4 85720.0 12100.0 0.91 0.9274 0.9303 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D01 compound treatment 52240.0 -31700.0 -1.83 33720.0 -39900.0 -3.02 -3.4339 -0.9714 3086852 TimTec1_007107 Oc1ccc(cc1)N(Cc2cccs2)C3=NS(=O)(=O)c4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D02 compound treatment 21960.0 -61900.0 -3.59 18120.0 -55500.0 -4.2 -5.5094 -0.9969 1609213 TimTec1_007108 Clc1ccc(cc1)c2csc(n2)N3CCNC(=O)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D03 compound treatment 71120.0 -12800.0 -0.74 69320.0 -4320.0 -0.33 -0.755 -0.9325 1349191 TimTec1_007109 Cc1ccc(NC(=O)CC2(C)Nc3ccccc3C(=O)N2c4ccccc4C)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D04 compound treatment 69360.0 -14500.0 -0.84 54040.0 -19600.0 -1.48 -1.6449 -0.9641 1386349 TimTec1_007110 CCCCc1c(nc(N)c(C#N)c1c2ccc(O)c(OC)c2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D05 compound treatment 96720.0 12800.0 0.74 70680.0 -2960.0 -0.22 0.3666 0.4727 3086855 TimTec1_007111 Cc1ccccc1C(=O)N(CC#N)CC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D06 compound treatment 70600.0 -13300.0 -0.77 56560.0 -17100.0 -1.29 -1.4593 -0.9695 3212367 TimTec1_007112 Fc1ccc(NC(=O)CSc2ccccc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D07 compound treatment 52000.0 -31900.0 -1.85 38640.0 -35000.0 -2.65 -3.1804 -0.9845 1055578 TimTec1_007113 Cc1nc2cc(Cl)ccc2n1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D08 compound treatment 95880.0 12000.0 0.69 67080.0 -6560.0 -0.5 0.1395 0.1635 1411696 TimTec1_007114 Cc1nc2c(nc(C)nc2o1)n3cc(F)c(=O)[nH]c3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D09 compound treatment 80400.0 -3500.0 -0.2 66200.0 -7440.0 -0.56 -0.5418 -0.905 1520665 TimTec1_007115 NNC(=O)CC(=O)NC1(Cc2ccc(O)cc2)CCCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D10 compound treatment 82560.0 -1340.0 -0.08 66880.0 -6760.0 -0.51 -0.4169 -0.8055 1312726 TimTec1_007116 CCOc1ccc2[nH]c(=O)c(cc2c1)C(N3CCc4ccccc34)c5nnnn5CCOC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D11 compound treatment 80320.0 -3580.0 -0.21 68400.0 -5240.0 -0.4 -0.4273 -0.9544 1686790 TimTec1_007117 CC(=O)N(c1ccccc1)c2nc(C)cc(C)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D12 compound treatment 81920.0 -1980.0 -0.11 70320.0 -3320.0 -0.25 -0.259 -0.9372 3086859 TimTec1_007118 OC(=O)c1cccc2CN(C3CCCCC3)C(=O)c21 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D13 compound treatment 77760.0 -6140.0 -0.36 61160.0 -12500.0 -0.94 -0.9197 -0.911 3212368 TimTec1_007119 Cc1ccc(cc1F)N(C(C(=O)NC2CCCC2)c3cccs3)C(=O)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D14 compound treatment 70280.0 -13600.0 -0.79 59240.0 -14400.0 -1.09 -1.3289 -0.9874 3086861 TimTec1_007120 COc1cccc(c1)N(C(C(=O)NC2CCCC2)c3cccs3)C(=O)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D15 compound treatment 79080.0 -4820.0 -0.28 65280.0 -8360.0 -0.63 -0.6451 -0.9325 3086982 TimTec1_007121 CN1CCN(CC1)C(=O)c2cc(cc(c2)C(C)(C)C)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D16 compound treatment 50840.0 -33100.0 -1.92 51480.0 -22200.0 -1.68 -2.5407 -0.9978 3212443 TimTec1_007122 COc1cc(cc(OC)c1OC)C(=O)N(Cc2ccccc2)Cc3cc4ccc(C)cc4[nH]c3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D17 compound treatment 70680.0 -13200.0 -0.77 69440.0 -4200.0 -0.32 -0.7666 -0.9241 1384457 TimTec1_007123 CN(Cc1ccccc1)C(=O)COc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D18 compound treatment 65960.0 -17900.0 -1.04 63720.0 -9920.0 -0.75 -1.2661 -0.9872 1679436 TimTec1_007124 COc1ccc2CCc3sc(N)nc3-c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D19 compound treatment 80240.0 -3660.0 -0.21 70200.0 -3440.0 -0.26 -0.3343 -0.9949 1259187 TimTec1_007125 O=C1N(CN2CCN(Cc3ccc4OCOc4c3)CC2)C(=O)c5ccccc15 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D20 compound treatment 80560.0 -3340.0 -0.19 67800.0 -5840.0 -0.44 -0.4496 -0.9315 3086919 TimTec1_007126 CC(C)(C)c1cc(c2c(N)c(sc2n1)C(=O)NC3CC3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D21 compound treatment 96920.0 13000.0 0.75 75080.0 1440.0 0.11 0.6103 0.801 3212444 TimTec1_007127 CCN(CC)Cc1cc(C(=O)O)c(o1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D22 compound treatment 95640.0 11700.0 0.68 84680.0 11000.0 0.84 1.0717 0.9948 1398660 TimTec1_007128 Cc1cc(C(=O)O)c2cc(O)ccc2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D23 mock treatment 89240.0 5340.0 0.31 76480.0 2840.0 0.21 0.3706 0.9842 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 D24 mock treatment 86120.0 2220.0 0.13 76280.0 2640.0 0.2 0.2321 0.9771 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E01 compound treatment 88960.0 5060.0 0.29 68040.0 -5600.0 -0.42 -0.0926 -0.1798 1226206 TimTec1_007129 CC(C)(C)CC(=O)Nc1nc2ccc(cc2s1)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E02 compound treatment 78720.0 -5180.0 -0.3 59800.0 -13800.0 -1.05 -0.9532 -0.8746 1700538 TimTec1_007130 CCNc1nc2nonc2nc1NCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E03 compound treatment 67920.0 -16000.0 -0.93 60040.0 -13600.0 -1.03 -1.3828 -0.9986 1567862 TimTec1_007131 Oc1c(C(=O)NC2CCCC2)c(=O)n3CCc4cccc1c43 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E04 compound treatment 89680.0 5780.0 0.33 73680.0 40.0 0.0 0.2388 0.7135 1647305 TimTec1_007132 Cc1cc(on1)C2C(CC(=O)CC2=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E05 compound treatment 80120.0 -3780.0 -0.22 59440.0 -14200.0 -1.07 -0.9151 -0.8342 1721107 TimTec1_007133 COc1cc(OC)cc(c1)C(=O)Nc2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E06 compound treatment 55040.0 -28900.0 -1.67 38920.0 -34700.0 -2.63 -3.0409 -0.9762 1113188 TimTec1_007134 COc1ccc(cc1)c2onc3ccc(Cl)cc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E07 compound treatment 74120.0 -9780.0 -0.57 52400.0 -21200.0 -1.61 -1.5377 -0.902 3212445 TimTec1_007135 COc1c2C=CC(=O)C(CC=C(C)C)(OC)c2nc3occc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E08 compound treatment 68720.0 -15200.0 -0.88 58640.0 -15000.0 -1.14 -1.4249 -0.992 1237484 TimTec1_007136 Cc1cc(C)nc(NCC(O)CNc2ccccc2C)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E09 compound treatment 44880.0 -39000.0 -2.26 37960.0 -35700.0 -2.7 -3.5085 -0.9961 1749456 TimTec1_007137 CCOc1ccc(NC(=O)c2cnccn2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E10 compound treatment 71080.0 -12800.0 -0.74 55920.0 -17700.0 -1.34 -1.4738 -0.9612 1786928 TimTec1_007138 CCOc1ccc2nc(SCC(=O)OC3CCCCC3)c(C)cc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E11 compound treatment 81440.0 -2460.0 -0.14 71960.0 -1680.0 -0.13 -0.1909 -0.9983 1398984 TimTec1_007139 Clc1ccc(cc1)n2c(=O)c3cc4c(=O)n(c5ccc(Cl)cc5)c(=O)c4cc3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E12 compound treatment 74960.0 -8940.0 -0.52 62520.0 -11100.0 -0.84 -0.9616 -0.9729 1228877 TimTec1_007140 C(Nc1c2CCCc2nc3ccccc13)c4cccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E13 compound treatment 73360.0 -10500.0 -0.61 64760.0 -8880.0 -0.67 -0.9073 -0.9989 3212446 TimTec1_007141 COC(=O)CC1OC(=O)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E14 compound treatment 71320.0 -12600.0 -0.73 78400.0 4760.0 0.36 -0.2608 -0.3207 1386546 TimTec1_007142 CC1CC(C)CN(CCC(=O)Nc2ccccc2)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E15 compound treatment 26400.0 -57500.0 -3.33 33320.0 -40300.0 -3.05 -4.5139 -0.999 1311552 TimTec1_007143 O=C(Nc1ccncc1)C2COc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E16 compound treatment 56880.0 -27000.0 -1.57 54240.0 -19400.0 -1.47 -2.1455 -0.9995 1687129 TimTec1_007144 O=C(NCC1CCCO1)c2ccc(CN3CCc4ccccc4C3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E17 compound treatment 45560.0 -38300.0 -2.22 46040.0 -27600.0 -2.09 -3.0482 -0.9995 3212447 TimTec1_007145 CCCCc1n[nH]c2CC(C/C(=N/O)/c12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E18 compound treatment 82360.0 -1540.0 -0.09 68800.0 -4840.0 -0.37 -0.3223 -0.8547 1208623 TimTec1_007146 CCCc1nc2ccccc2n1CC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E19 compound treatment 79680.0 -4220.0 -0.24 74640.0 1000.0 0.08 -0.1195 -0.4666 3212448 TimTec1_007147 CCN(CC)CC(=O)OC1CC2CCC1(C)C2(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E20 compound treatment 70840.0 -13100.0 -0.76 66360.0 -7280.0 -0.55 -0.9249 -0.9878 1568959 TimTec1_007148 CC1CCc2c(C(=O)N3CCCCC3)c(NC(=O)c4ccccc4)sc2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E21 compound treatment 81040.0 -2860.0 -0.17 64320.0 -9320.0 -0.71 -0.6162 -0.8502 1089037 TimTec1_007149 O=C(Nc1ccccc1)C2C(C3CC2C=C3)C(=O)Nc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E22 compound treatment 95040.0 11100.0 0.65 74040.0 400.0 0.03 0.4776 0.7395 1510856 TimTec1_007150 COc1ccc(NC(=O)CCN2CCCCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E23 mock treatment 90680.0 6780.0 0.39 80600.0 6960.0 0.53 0.6501 0.9895 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 E24 mock treatment 94480.0 10600.0 0.61 76320.0 2680.0 0.2 0.5767 0.8935 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F01 compound treatment 110520.0 26600.0 1.54 72880.0 -760.0 -0.06 1.0497 0.6803 3212449 TimTec1_007151 COc1ccc(cc1)C(O)CNc2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F02 compound treatment 97440.0 13500.0 0.78 79280.0 5640.0 0.43 0.8564 0.9591 1155968 TimTec1_007152 CC(C)C1Nc2ccc(cc2C3C=CCC31)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F03 compound treatment 86200.0 2300.0 0.13 71280.0 -2360.0 -0.18 -0.0323 -0.1449 1259120 TimTec1_007153 CC(=O)Nc1c([nH]c2ccccc12)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F04 compound treatment 81600.0 -2300.0 -0.13 68400.0 -5240.0 -0.4 -0.3749 -0.8957 3212450 TimTec1_007154 Cc1ccc2[nH]c(=O)c(CN(C3CCCCC3)C(=O)c4cccs4)cc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F05 compound treatment 92200.0 8300.0 0.48 76880.0 3240.0 0.25 0.5133 0.9512 1251350 TimTec1_007155 COc1ccc(CNCc2ccco2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F06 compound treatment 83000.0 -905.0 -0.05 70360.0 -3280.0 -0.25 -0.2126 -0.8379 1187651 TimTec1_007156 OCc1ccccc1CNC2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F07 compound treatment 78760.0 -5140.0 -0.3 61520.0 -12100.0 -0.92 -0.8595 -0.891 3086933 TimTec1_007157 Clc1ccc(Cn2nnc(n2)c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F08 compound treatment 86440.0 2540.0 0.15 67120.0 -6520.0 -0.49 -0.2451 -0.476 1430421 TimTec1_007158 Cc1cccc(NC(=O)C2(CCOCC2)c3ccccc3)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F09 compound treatment 55560.0 -28300.0 -1.64 54360.0 -19300.0 -1.46 -2.1932 -0.9983 1706906 TimTec1_007159 O=C(Cc1cccs1)Nc2cccc(c2)c3nnc(o3)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F10 compound treatment 82320.0 -1580.0 -0.09 69760.0 -3880.0 -0.29 -0.2726 -0.8859 1276179 TimTec1_007160 OCC(C(=O)OC1CN2CCC1CC2)(c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F11 compound treatment 81560.0 -2340.0 -0.14 70760.0 -2880.0 -0.22 -0.2502 -0.9741 1576381 TimTec1_007161 CCN1CCN(CC1)C(=O)c2ccc(NC(=O)C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F12 compound treatment 64800.0 -19100.0 -1.11 63480.0 -10200.0 -0.77 -1.3265 -0.9842 1346949 TimTec1_007162 O=C(NC(c1ccccc1)c2ccccc2)C3COC4C=CC=CC4O3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F13 compound treatment 74720.0 -9180.0 -0.53 71520.0 -2120.0 -0.16 -0.4897 -0.8812 3086988 TimTec1_007163 CCCN1C(=O)C(O)(C/C(=N\O)/C)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F14 compound treatment 56800.0 -27100.0 -1.57 57040.0 -16600.0 -1.26 -1.9989 -0.9939 1714688 TimTec1_007164 Cc1ccc(cc1)C2(CC(=O)Nc3ccccc3C)CCOC(C)(C)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F15 compound treatment 72480.0 -11400.0 -0.66 71560.0 -2080.0 -0.16 -0.5794 -0.8515 1704815 TimTec1_007165 O=C(Cc1cccs1)NC(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F16 compound treatment 74960.0 -8940.0 -0.52 63360.0 -10300.0 -0.78 -0.9167 -0.9805 3212451 TimTec1_007166 O=C(NC1CCCC1)C(N(Cc2cccs2)C(=O)c3csnn3)c4ccncc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F17 compound treatment 81600.0 -2300.0 -0.13 71000.0 -2640.0 -0.2 -0.2357 -0.9808 3086991 TimTec1_007167 CCCC(NC(=O)c1ccco1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F18 compound treatment 88280.0 4380.0 0.25 74840.0 1200.0 0.09 0.2435 0.9042 1420604 TimTec1_007168 C(CN1CCNCC1)OC(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F19 compound treatment 41040.0 -42900.0 -2.48 48400.0 -25200.0 -1.91 -3.107 -0.9916 1477182 TimTec1_007169 O=C(CC1c2ccccc2Oc3ccccc13)NCc4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F20 compound treatment 89800.0 5900.0 0.34 71040.0 -2600.0 -0.2 0.1024 0.2597 3212452 TimTec1_007170 COc1ccc(cc1)C(=O)CN2C(=O)COc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F21 compound treatment 98320.0 14400.0 0.84 74120.0 480.0 0.04 0.6163 0.7372 3086994 TimTec1_007171 CCc1ccc(CN2CCNCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F22 compound treatment 95880.0 12000.0 0.69 80480.0 6840.0 0.52 0.8567 0.9896 3212453 TimTec1_007172 O=C(CSc1nc2ccccc2c(=O)[nH]1)Nc3ccccc3N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F23 mock treatment 96480.0 12600.0 0.73 81520.0 7880.0 0.6 0.937 0.9951 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 F24 mock treatment 90360.0 6460.0 0.37 86080.0 12400.0 0.94 0.9303 0.9182 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G01 compound treatment 101160.0 17300.0 1.0 70960.0 -2680.0 -0.2 0.5635 0.5524 3086996 TimTec1_007173 Cc1cc(C)nc(SCC(=O)C2CC2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G02 compound treatment 87800.0 3900.0 0.23 68200.0 -5440.0 -0.41 -0.1316 -0.2802 1541773 TimTec1_007174 COc1ccc2nc(sc2c1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G03 compound treatment 90320.0 6420.0 0.37 65200.0 -8440.0 -0.64 -0.1889 -0.2556 1164972 TimTec1_007175 Oc1cccnc1NC(=O)c2c(O)c3cccc4CCn(c2=O)c43 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G04 compound treatment 77960.0 -5940.0 -0.34 51800.0 -21800.0 -1.65 -1.4125 -0.8365 1545465 TimTec1_007176 CC(C)CC(=O)N1CCN(CC1)C(=O)COc2ccc(cc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G05 compound treatment 83200.0 -705.0 -0.04 65440.0 -8200.0 -0.62 -0.4678 -0.752 1921627 TimTec1_007177 OC1CC(N(Cc2ccccc2)C1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G06 compound treatment 79760.0 -4140.0 -0.24 66600.0 -7040.0 -0.53 -0.5466 -0.9352 1246123 TimTec1_007178 CC(C)C(=O)Nc1sc(C)c(C)c1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G07 compound treatment 32000.0 -51900.0 -3.01 40120.0 -33500.0 -2.54 -3.9206 -0.9964 1253428 TimTec1_007179 Brc1ccc(cc1)C(=O)CCN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G08 compound treatment 81520.0 -2380.0 -0.14 67360.0 -6280.0 -0.48 -0.4338 -0.8764 1492540 TimTec1_007180 CCc1ccc(cc1)c2ccc(C(=O)O)n2C=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G09 compound treatment 68360.0 -15500.0 -0.9 63920.0 -9720.0 -0.74 -1.1571 -0.995 1193373 TimTec1_007181 O=C(Cn1nnc(n1)c2ccccc2)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G10 compound treatment 84320.0 415.0 0.02 72720.0 -920.0 -0.07 -0.0322 -0.4373 1348653 TimTec1_007182 CN(C)CCOC(=O)c1cc2ccccc2o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G11 compound treatment 42000.0 -41900.0 -2.43 45920.0 -27700.0 -2.1 -3.2004 -0.9974 3212764 TimTec1_007183 CC(C)CSc1ncnc2scc(c3ccccc3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G12 compound treatment 62760.0 -21100.0 -1.23 62400.0 -11200.0 -0.85 -1.4679 -0.9841 3087000 TimTec1_007184 CCSc1cc(C)nc(NC(=O)CC)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G13 compound treatment 46400.0 -37500.0 -2.17 46400.0 -27200.0 -2.06 -2.9945 -0.9997 3212765 TimTec1_007185 CC1(CC2CC(C)(C)C1)CN2C(=O)c3ccccc3NC(=O)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G14 compound treatment 2040.0 -81900.0 -4.74 2720.0 -70900.0 -5.37 -7.1498 -0.9981 1024239 TimTec1_007186 COc1ccc(cc1)C(=O)CCN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G15 compound treatment 49560.0 -34300.0 -1.99 56160.0 -17500.0 -1.32 -2.3426 -0.9803 1148203 TimTec1_007187 Nc1c(C#N)c(NCC=C)sc1C(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G16 compound treatment 45440.0 -38500.0 -2.23 42720.0 -30900.0 -2.34 -3.2308 -0.9997 3087003 TimTec1_007188 O=c1[nH]cnc2c1sc3nc(cc(c4ccccc4)c32)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G17 compound treatment 60040.0 -23900.0 -1.38 51680.0 -22000.0 -1.66 -2.1531 -0.9958 1761275 TimTec1_007189 Cc1cccc2cc(CN(Cc3ccccc3)C(=O)c4ccccc4)c(=O)[nH]c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G18 compound treatment 67080.0 -16800.0 -0.97 60920.0 -12700.0 -0.96 -1.3701 -1.0 1350623 TimTec1_007190 Clc1ccccc1C2CC(=O)NC(=C2C#N)SCC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G19 compound treatment 84800.0 895.0 0.05 73360.0 -280.0 -0.02 0.0217 0.3872 1434575 TimTec1_007191 CC(SCCc1ccccn1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G20 compound treatment 73560.0 -10300.0 -0.6 67920.0 -5720.0 -0.43 -0.73 -0.9873 1246459 TimTec1_007192 CCOC(=O)C1=C(N)OC2=C(C1c3ccc(OC)cc3)C(=O)CCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G21 compound treatment 88080.0 4180.0 0.24 65360.0 -8280.0 -0.63 -0.2721 -0.405 1436571 TimTec1_007193 Cc1ccc(cc1)c2cc3nc(cc(N)n3n2)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G22 compound treatment 69840.0 -14100.0 -0.81 67040.0 -6600.0 -0.5 -0.9295 -0.9724 1384558 TimTec1_007194 Clc1ccccc1NC(=O)C2(CCOCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G23 mock treatment 89320.0 5420.0 0.31 80560.0 6920.0 0.52 0.5922 0.97 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 G24 mock treatment 88720.0 4820.0 0.28 72680.0 -960.0 -0.07 0.1459 0.5061 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H01 compound treatment 84400.0 495.0 0.03 52320.0 -21300.0 -1.61 -1.1208 -0.6944 1215845 TimTec1_007195 Cc1cc(C(=O)OCC(=O)c2cccs2)c3ccccc3n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H02 compound treatment 86840.0 2940.0 0.17 71200.0 -2440.0 -0.18 -0.0103 -0.0412 1761483 TimTec1_007196 Cc1ccc2[nH]c(=O)c(CN(CC3CCCO3)C(=O)c4ccco4)cc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H03 compound treatment 49280.0 -34600.0 -2.01 44000.0 -29600.0 -2.24 -3.005 -0.9984 3212766 TimTec1_007197 CC(C)OC(=O)CSc1ncnc2scc(c3ccccc3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H04 compound treatment 87680.0 3780.0 0.22 71640.0 -2000.0 -0.15 0.0476 0.179 3087045 TimTec1_007198 OC(=O)C1(CCCC1)S(=O)(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H05 compound treatment 88640.0 4740.0 0.27 70320.0 -3320.0 -0.25 0.0163 0.0438 1782560 TimTec1_007199 O=C(CCNc1n[nH]c(=O)[nH]c1=O)NCc2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H06 compound treatment 71280.0 -12600.0 -0.73 57200.0 -16400.0 -1.24 -1.3971 -0.9679 1787855 TimTec1_007200 COc1ccccc1NC(=O)C(Cc2ccc(C)cc2)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H07 compound treatment 35440.0 -48500.0 -2.81 37840.0 -35800.0 -2.71 -3.9017 -0.9998 3212767 TimTec1_007201 Cc1ccc(N/C=C\2/C3CCC(C)(C2=O)C3(C)C)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H08 compound treatment 85240.0 1340.0 0.08 75120.0 1480.0 0.11 0.1339 0.9837 3212768 TimTec1_007202 CC1(C)CC(CCNCc2ccc3OCOc3c2)(Cc4ccccc4)CCO1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H09 compound treatment 81760.0 -2140.0 -0.12 67320.0 -6320.0 -0.48 -0.4261 -0.8622 3087048 TimTec1_007203 CN1CCN(CC1)c2nc(nc3ccccc23)N4CCN(CCO)CC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H10 compound treatment 82920.0 -985.0 -0.06 69200.0 -4440.0 -0.34 -0.278 -0.8155 1914315 TimTec1_007204 CC(=O)N/C(=C\c1ccccc1)/C(=O)Nc2ccc(O)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H11 compound treatment 28400.0 -55500.0 -3.22 38680.0 -35000.0 -2.65 -4.1451 -0.9953 1295223 TimTec1_007205 Cc1ccc(cc1)C(=O)c2c(NC(=O)c3ccncc3)sc4CCCCc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H12 compound treatment 62560.0 -21300.0 -1.24 60760.0 -12900.0 -0.97 -1.5638 -0.9931 3087050 TimTec1_007206 OC(=O)CSc1ncnc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H13 compound treatment 56400.0 -27500.0 -1.59 56280.0 -17400.0 -1.31 -2.056 -0.9954 1660199 TimTec1_007207 CCOc1cc(CN2CCN(CC2)C(=O)CC(C)C)ccc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H14 compound treatment 72880.0 -11000.0 -0.64 73240.0 -400.0 -0.03 -0.4731 -0.7398 1413084 TimTec1_007208 OC(=O)CSCC(=O)Nc1ccccc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H15 compound treatment 69840.0 -14100.0 -0.81 69520.0 -4120.0 -0.31 -0.7967 -0.9131 1396450 TimTec1_007209 COc1ccc(cc1)c2ccc(CCC(=O)O)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H16 compound treatment 77160.0 -6740.0 -0.39 67320.0 -6320.0 -0.48 -0.6146 -0.995 3212769 TimTec1_007210 O=S(=O)(NC1CC2CCC1C2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H17 compound treatment 62920.0 -21000.0 -1.22 56640.0 -17000.0 -1.29 -1.7696 -0.9996 1132422 TimTec1_007211 CC(C)CCNC(=O)C1CCN(Cc2cccc(OCc3ccccc3)c2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H18 compound treatment 46560.0 -37300.0 -2.16 48640.0 -25000.0 -1.89 -2.868 -0.9978 1184017 TimTec1_007212 Oc1c(ccc2cccnc12)C(NC(=O)c3ccccc3)c4ccc5OCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H19 compound treatment 51800.0 -32100.0 -1.86 65160.0 -8480.0 -0.64 -1.7691 -0.8991 1526246 TimTec1_007213 CCOc1ccc(cc1)c2cn3CCn4cccc4-c3c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H20 compound treatment 83200.0 -705.0 -0.04 75840.0 2200.0 0.17 0.0889 0.5184 1615914 TimTec1_007214 C(C1CCCCC1)N2CCN(Cc3ccccc3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H21 compound treatment 91560.0 7660.0 0.44 68240.0 -5400.0 -0.41 0.0246 0.0408 3212770 TimTec1_007215 FC(F)(F)C(=O)N(Cc1ccccc1)C(C(=O)NC2CCCC2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H22 compound treatment 73240.0 -10700.0 -0.62 64200.0 -9440.0 -0.71 -0.9422 -0.9974 1324827 TimTec1_007216 COc1ccc(CNC(C)c2ccccc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H23 mock treatment 89280.0 5380.0 0.31 71840.0 -1800.0 -0.14 0.1239 0.3644 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 H24 mock treatment 77080.0 -6820.0 -0.4 72440.0 -1200.0 -0.09 -0.3438 -0.8475 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I01 compound treatment 79960.0 -3940.0 -0.23 58920.0 -14700.0 -1.11 -0.9495 -0.8348 3087054 TimTec1_007217 CCN(CC)C(=O)c1sc2nc(cc(c2c1N)C(F)(F)F)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I02 compound treatment 82440.0 -1460.0 -0.08 69160.0 -4480.0 -0.34 -0.2998 -0.8576 3212771 TimTec1_007218 COc1cccc2cc(C(=O)Nc3ccccc3c4nnn(CC(=O)NC(C)(C)C)n4)c(=O)oc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I03 compound treatment 65040.0 -18900.0 -1.09 55560.0 -18100.0 -1.37 -1.7406 -0.9938 1785833 TimTec1_007219 CCCNC(=O)c1c(O)c2CCCCc2[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I04 compound treatment 78760.0 -5140.0 -0.3 67280.0 -6360.0 -0.48 -0.5512 -0.9734 1143730 TimTec1_007220 CC1(C)CC(CCO1)(C(CO)CNCc2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I05 compound treatment 72720.0 -11200.0 -0.65 65760.0 -7880.0 -0.6 -0.88 -0.9991 1623536 TimTec1_007221 OC1=C(COC1=O)C(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I06 compound treatment 69560.0 -14300.0 -0.83 63240.0 -10400.0 -0.79 -1.1443 -0.9996 1590931 TimTec1_007222 O=S(=O)(CC(CN1CCCCC1)N2CCCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I07 compound treatment 73880.0 -10000.0 -0.58 66360.0 -7280.0 -0.55 -0.8003 -0.9997 1668547 TimTec1_007223 Oc1ccc(cc1)c2cccc(n2)c3ccc(O)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I08 compound treatment 89440.0 5540.0 0.32 70880.0 -2760.0 -0.21 0.0791 0.2065 1147480 TimTec1_007224 Cc1c(C#N)c(NC(=O)c2cccs2)sc1C(=O)N3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I09 compound treatment 48840.0 -35100.0 -2.03 49600.0 -24000.0 -1.82 -2.7232 -0.9985 1394770 TimTec1_007225 OCCCc1cn(c2ccccc2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I10 compound treatment 26600.0 -57300.0 -3.32 31880.0 -41800.0 -3.16 -4.5828 -0.9997 1050975 TimTec1_007226 Cc1ccc(cc1)c2nnc(o2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I11 compound treatment 60280.0 -23600.0 -1.37 63520.0 -10100.0 -0.77 -1.5095 -0.9624 1459697 TimTec1_007227 COc1cc(NC(=O)CCN2CCC(C)CC2)cc(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I12 compound treatment 63840.0 -20100.0 -1.16 68880.0 -4760.0 -0.36 -1.0768 -0.8847 1104871 TimTec1_007228 COC(=O)c1ccc2[n+]([O-])onc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I13 compound treatment 57040.0 -26900.0 -1.56 56240.0 -17400.0 -1.32 -2.0319 -0.9965 1491293 TimTec1_007229 COc1ccc2CC(O)c3cc4OCOc4cc3CCN(C)Cc2c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I14 compound treatment 70240.0 -13700.0 -0.79 67480.0 -6160.0 -0.47 -0.8895 -0.9681 3087121 TimTec1_007230 CC(Oc1ccccc1)C(=O)Nc2nnc(s2)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I15 compound treatment 56560.0 -27300.0 -1.58 54920.0 -18700.0 -1.42 -2.1222 -0.9985 1557638 TimTec1_007231 O=C(CCN1CCc2ccccc2C1)Nc3ccc4CCCc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I16 compound treatment 84400.0 495.0 0.03 68000.0 -5640.0 -0.43 -0.2816 -0.6581 1332636 TimTec1_007232 NC(=O)CC1Sc2ccccc2NC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I17 compound treatment 79080.0 -4820.0 -0.28 75320.0 1680.0 0.13 -0.1077 -0.3508 1711213 TimTec1_007233 CN(CCC(=O)Nc1ccc2OCOc2c1)Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I18 compound treatment 55640.0 -28300.0 -1.64 48960.0 -24700.0 -1.87 -2.4789 -0.9978 3212772 TimTec1_007234 O=C(Nc1ccc(cc1)S(=O)(=O)N2CCCC2)/C=C/c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I19 compound treatment 71040.0 -12900.0 -0.75 64120.0 -9520.0 -0.72 -1.0366 -0.9999 3087124 TimTec1_007235 CC1Oc2ccccc2OC1C(=O)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I20 compound treatment 22400.0 -61500.0 -3.56 23880.0 -49800.0 -3.77 -5.1831 -0.9996 1059391 TimTec1_007236 N1NC(=NN=C1c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I21 compound treatment 81720.0 -2180.0 -0.13 69280.0 -4360.0 -0.33 -0.3229 -0.9134 1417338 TimTec1_007237 CCCCN(C)C(=O)C1CCN(Cc2ccc(OCC)cc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I22 compound treatment 54600.0 -29300.0 -1.7 42440.0 -31200.0 -2.36 -2.8705 -0.9869 1447122 TimTec1_007238 O=C(COC(=O)c1ccccc1c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I23 mock treatment 91760.0 7860.0 0.46 77360.0 3720.0 0.28 0.5209 0.9734 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 I24 mock treatment 80880.0 -3020.0 -0.18 70200.0 -3440.0 -0.26 -0.308 -0.9814 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J01 compound treatment 37600.0 -46300.0 -2.68 32520.0 -41100.0 -3.11 -4.0979 -0.9973 3087127 TimTec1_007239 O=C(CCCc1ccccc1)Nc2ccc3OCCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J02 compound treatment 80840.0 -3060.0 -0.18 68400.0 -5240.0 -0.4 -0.406 -0.9343 1381726 TimTec1_007240 CC(C)CC(=O)N1C(C2=C(CC(C)(C)CC2=O)Nc3ccccc13)c4cccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J03 compound treatment 86520.0 2620.0 0.15 65320.0 -8320.0 -0.63 -0.3382 -0.5221 3087128 TimTec1_007241 O=C(Cc1ccccc1)N2CCN(CC2)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J04 compound treatment 55600.0 -28300.0 -1.64 50320.0 -23300.0 -1.77 -2.4078 -0.9993 3212853 TimTec1_007242 COC(=O)C1=CN(CCc2ccc(OC)cc2)C=C(C1c3ccsc3)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J05 compound treatment 46080.0 -37800.0 -2.19 45640.0 -28000.0 -2.12 -3.0483 -0.9999 3087130 TimTec1_007243 O=C(NCCC1=CCCCC1)c2ccc3snnc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J06 compound treatment 66640.0 -17300.0 -1.0 60760.0 -12900.0 -0.97 -1.3967 -0.9999 3212854 TimTec1_007244 Cc1ccc2nc(NC(=O)C(F)(F)F)sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J07 compound treatment 72240.0 -11700.0 -0.68 66320.0 -7320.0 -0.55 -0.8697 -0.9951 3212855 TimTec1_007245 O=C(CC1CC2CCC1C2)NCc3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J08 compound treatment 66000.0 -17900.0 -1.04 62080.0 -11600.0 -0.88 -1.3523 -0.9964 3087132 TimTec1_007246 CCCC(C)C(=O)Nc1nnc(s1)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J09 compound treatment 73720.0 -10200.0 -0.59 63320.0 -10300.0 -0.78 -0.9696 -0.9904 1343394 TimTec1_007247 Cc1ccc(cc1)c2ccc(CCC(=O)O)[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J10 compound treatment 50160.0 -33700.0 -1.96 51680.0 -22000.0 -1.66 -2.5578 -0.9967 3087133 TimTec1_007248 CN(C)c1ccc(cc1)C(CC=C)NCc2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J11 compound treatment 55960.0 -27900.0 -1.62 55280.0 -18400.0 -1.39 -2.1275 -0.9971 1169499 TimTec1_007249 CC(C)CNC(=O)c1ccc(Br)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J12 compound treatment 61040.0 -22900.0 -1.32 58560.0 -15100.0 -1.14 -1.7439 -0.9973 1620830 TimTec1_007250 NS(=O)(=O)c1cccc(c1)C(=O)NCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J13 compound treatment 51040.0 -32900.0 -1.9 57160.0 -16500.0 -1.25 -2.2285 -0.979 1204293 TimTec1_007251 Nc1ncnc2[nH]c(SCc3nc4ccccc4n3Cc5ccccc5)nc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J14 compound treatment 74840.0 -9060.0 -0.53 71360.0 -2280.0 -0.17 -0.4934 -0.8925 1737852 TimTec1_007252 OC(=O)c1ccc(cc1)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J15 compound treatment 65480.0 -18400.0 -1.07 56880.0 -16800.0 -1.27 -1.6519 -0.9963 3212856 TimTec1_007253 CCCC(C)C(=O)Nc1nnc(Cc2ccc(OC)cc2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J16 compound treatment 67280.0 -16600.0 -0.96 58920.0 -14700.0 -1.11 -1.4689 -0.9974 1787669 TimTec1_007254 OC(COCC1CCC=CC1)CN(Cc2ccccc2)Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J17 compound treatment 80080.0 -3820.0 -0.22 71960.0 -1680.0 -0.13 -0.2466 -0.9653 1458427 TimTec1_007255 Oc1ccc(CN2CCCCC2)nc1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J18 compound treatment 75200.0 -8700.0 -0.5 67120.0 -6520.0 -0.49 -0.7056 -0.9999 1535978 TimTec1_007256 Oc1ccc2ccccc2c1C(NC(=O)CCc3ccccc3)c4ccc5OCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J19 compound treatment 81680.0 -2220.0 -0.13 62560.0 -11100.0 -0.84 -0.6842 -0.8063 1729058 TimTec1_007257 CCOC(=O)c1c[nH]c2c(cccc2c1=O)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J20 compound treatment 18800.0 -65100.0 -3.77 16320.0 -57300.0 -4.34 -5.7352 -0.9976 1266090 TimTec1_007258 O=C(N1CCN(CC1)c2ncnc3sc4CCCCc4c23)c5ccco5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J21 compound treatment 86080.0 2180.0 0.13 61840.0 -11800.0 -0.89 -0.5425 -0.6014 1722077 TimTec1_007259 OC(=O)C1CNC(S1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J22 compound treatment 74880.0 -9020.0 -0.52 66160.0 -7480.0 -0.57 -0.7701 -0.9992 1633478 TimTec1_007260 OC(=O)c1c(NC(=O)c2ccc(F)cc2)scc1c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J23 mock treatment 84040.0 135.0 0.01 74680.0 1040.0 0.08 0.0612 0.7738 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 J24 mock treatment 81120.0 -2780.0 -0.16 77000.0 3360.0 0.25 0.0658 0.2184 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K01 compound treatment 45080.0 -38800.0 -2.25 28520.0 -45100.0 -3.42 -4.0056 -0.9795 3087134 TimTec1_007261 Nc1c(sc2nc(cc(c12)C(F)(F)F)c3cccs3)C(=O)N4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K02 compound treatment 68040.0 -15900.0 -0.92 59840.0 -13800.0 -1.04 -1.3886 -0.998 3212857 TimTec1_007262 Cc1cnc(cn1)C(=O)Nc2ccccc2c3nnn(CC(=O)NC4CCCC4)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K03 compound treatment 77720.0 -6180.0 -0.36 61120.0 -12500.0 -0.95 -0.9235 -0.9115 1132974 TimTec1_007263 CC1CCCN(C1)C(=O)C2CCN(CC3CCCCC3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K04 compound treatment 36680.0 -47200.0 -2.74 26280.0 -47400.0 -3.58 -4.4696 -0.9911 3212858 TimTec1_007264 COC(=O)C1C(C(=C(CC1(C)O)Nc2ccc(C)cc2)C(=O)OC)c3ccc(Br)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K05 compound treatment 64320.0 -19600.0 -1.13 54200.0 -19400.0 -1.47 -1.8428 -0.9918 1418415 TimTec1_007265 COc1ccc(cc1OC)C(C)N(C)CCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K06 compound treatment 67400.0 -16500.0 -0.96 55440.0 -18200.0 -1.38 -1.6503 -0.9841 1367310 TimTec1_007266 OC(=O)C1CN(C(=O)C1)c2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K07 compound treatment 65560.0 -18300.0 -1.06 57720.0 -15900.0 -1.21 -1.6036 -0.998 1749464 TimTec1_007267 COC(=O)c1cccc(NC(=O)c2cnccn2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K08 compound treatment 75680.0 -8220.0 -0.48 64960.0 -8680.0 -0.66 -0.8015 -0.9876 1509871 TimTec1_007268 CCC(=O)Nc1nc2ccc(cc2s1)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K09 compound treatment 55360.0 -28500.0 -1.65 53360.0 -20300.0 -1.54 -2.2549 -0.9993 1244693 TimTec1_007269 CCN1CCCC1CNC(=O)c2ccccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K10 compound treatment 2720.0 -81200.0 -4.7 4240.0 -69400.0 -5.25 -7.0405 -0.9985 1569404 TimTec1_007270 C1CCN(CC1)c2ncnc3n(ncc23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K11 compound treatment 49640.0 -34300.0 -1.99 54720.0 -18900.0 -1.43 -2.4164 -0.9872 1600050 TimTec1_007271 Brc1ccc(cc1)C(=O)COC(=O)CSc2cccc3cccnc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K12 compound treatment 31360.0 -52500.0 -3.04 35440.0 -38200.0 -2.89 -4.1973 -0.9997 1451391 TimTec1_007272 Oc1ccccc1C(CC(=O)NCc2ccccc2)NCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K13 compound treatment 51160.0 -32700.0 -1.9 48880.0 -24800.0 -1.87 -2.6667 -1.0 1622555 TimTec1_007273 COC(C(=O)NCc1ccc(C)cc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K14 compound treatment 60480.0 -23400.0 -1.36 52320.0 -21300.0 -1.61 -2.1008 -0.9963 1244048 TimTec1_007274 OC(=O)C1(CCC(C1)Nc2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K15 compound treatment 60600.0 -23300.0 -1.35 46720.0 -26900.0 -2.04 -2.3956 -0.98 1530042 TimTec1_007275 O=C(CCC1CCCC1)N2CCN(CC2)C(=O)COc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K16 compound treatment 71920.0 -12000.0 -0.69 63240.0 -10400.0 -0.79 -1.0476 -0.998 1301695 TimTec1_007276 O=C(NCc1ccccc1)c2ccc(CN(c3ccccc3)S(=O)(=O)c4ccccc4)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K17 compound treatment 49200.0 -34700.0 -2.01 46440.0 -27200.0 -2.06 -2.8776 -0.9999 3087135 TimTec1_007277 FC(F)(F)c1cc(nc2cc(nn12)C(=O)N3CCSCC3)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K18 compound treatment 51680.0 -32200.0 -1.87 38680.0 -35000.0 -2.65 -3.1914 -0.9854 1164653 TimTec1_007278 Clc1ccc(NC(=O)CN(Cc2ccco2)C(=O)c3ccccc3)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K19 compound treatment 64000.0 -19900.0 -1.15 48560.0 -25100.0 -1.9 -2.1578 -0.9715 3087136 TimTec1_007279 CC(=O)Nc1nc(C)c(Cc2ccccc2)c(O)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K20 compound treatment 58840.0 -25100.0 -1.45 52840.0 -20800.0 -1.57 -2.1401 -0.9992 3212859 TimTec1_007280 COc1cc2CCN(C3CC4(C=CC(=O)C=C4)c(c32)c1OC)C(=O)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K21 compound treatment 64160.0 -19700.0 -1.14 50520.0 -23100.0 -1.75 -2.0464 -0.9788 1585233 TimTec1_007281 COc1ccc(cc1)C2N(CC=C)C(=O)C(=C2C(=O)c3ccccc3)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K22 compound treatment 64960.0 -18900.0 -1.1 51680.0 -22000.0 -1.66 -1.9515 -0.9797 3087182 TimTec1_007282 CC(C)CCNCC1OCc2ccccc2CO1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K23 mock treatment 73320.0 -10600.0 -0.61 59240.0 -14400.0 -1.09 -1.2044 -0.963 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 K24 mock treatment 69200.0 -14700.0 -0.85 60040.0 -13600.0 -1.03 -1.3303 -0.9956 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L01 compound treatment 86480.0 2580.0 0.15 58760.0 -14900.0 -1.13 -0.6909 -0.6081 1537215 TimTec1_007283 S=c1n(CN2CCOCC2)nnn1C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L02 compound treatment 83240.0 -665.0 -0.04 63880.0 -9760.0 -0.74 -0.5496 -0.7429 1303821 TimTec1_007284 COC(=O)C1=C(C)N(C)C(=O)NC1c2ccc(O)c(OC)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L03 compound treatment 82600.0 -1300.0 -0.08 67120.0 -6520.0 -0.49 -0.4024 -0.806 3087183 TimTec1_007285 COc1cccc(OC)c1C(=O)Nc2nnc(CC(C)(C)C)s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L04 compound treatment 79200.0 -4700.0 -0.27 60400.0 -13200.0 -1.0 -0.9014 -0.8679 3087184 TimTec1_007286 CCN(CC)Cc1c(CC(C)C)oc(C)c1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L05 compound treatment 60720.0 -23200.0 -1.34 48520.0 -25100.0 -1.9 -2.2943 -0.9855 3087185 TimTec1_007287 O=C(N1CCCCC1)c2ccc3snnc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L06 compound treatment 62360.0 -21500.0 -1.25 56640.0 -17000.0 -1.29 -1.7925 -0.9999 1320337 TimTec1_007288 Cc1ccc(NC(=O)CNc2ccccc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L07 compound treatment 58760.0 -25100.0 -1.46 47760.0 -25900.0 -1.96 -2.4153 -0.9894 3087186 TimTec1_007289 Cc1cccc2cc(C(N(Cc3ccco3)Cc4ccccc4)c5nnnn5C(C)(C)C)c(=O)[nH]c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L08 compound treatment 47240.0 -36700.0 -2.12 45920.0 -27700.0 -2.1 -2.9858 -1.0 1784505 TimTec1_007290 Cc1ccc(cc1)n2nc-3c(CCc4nonc43)[n+]2[O-] 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L09 compound treatment 64880.0 -19000.0 -1.1 65600.0 -8040.0 -0.61 -1.2097 -0.9608 1715611 TimTec1_007291 CC(C)c1ccc(cc1)N2CC(CC2=O)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L10 compound treatment 52200.0 -31700.0 -1.84 48040.0 -25600.0 -1.94 -2.6691 -0.9996 3212860 TimTec1_007292 FC(F)(F)C(=O)N(Cc1ccc2OCOc2c1)C(C(=O)NC3CCCCC3)c4ccccn4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L11 compound treatment 57080.0 -26800.0 -1.55 57880.0 -15800.0 -1.19 -1.9425 -0.9915 1196884 TimTec1_007293 CCCn1c(=O)c(c(O)c2ccccc12)c3nc4ccccc4c(=O)[nH]3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L12 compound treatment 42720.0 -41200.0 -2.39 45880.0 -27800.0 -2.1 -3.1731 -0.998 1066059 TimTec1_007294 CN1C(CC(=O)CC1c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L13 compound treatment 39160.0 -44700.0 -2.59 47080.0 -26600.0 -2.01 -3.2547 -0.9921 1212761 TimTec1_007295 CC1(C)OC(=O)N(c2ccccc2)C31Oc4cc5ccccc5cc4C=C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L14 compound treatment 67120.0 -16800.0 -0.97 54760.0 -18900.0 -1.43 -1.6982 -0.9824 3087187 TimTec1_007296 CC(C)N(C(C)C)c1nnc(N)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L15 compound treatment 76000.0 -7900.0 -0.46 62920.0 -10700.0 -0.81 -0.8976 -0.9633 3212861 TimTec1_007297 CCN(CC)CCCNc1ncnc2sc3CCC(C)Cc3c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L16 compound treatment 77000.0 -6900.0 -0.4 78400.0 4760.0 0.36 -0.0281 -0.0522 1625654 TimTec1_007298 C(CN1C2CCC1C=CC2)N3C4CCC3C=CC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L17 compound treatment 77480.0 -6420.0 -0.37 63360.0 -10300.0 -0.78 -0.8134 -0.943 3212862 TimTec1_007299 FC(F)(F)C(=O)NCc1ccc2OCOc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L18 compound treatment 75040.0 -8860.0 -0.51 71680.0 -1960.0 -0.15 -0.4681 -0.8756 3212863 TimTec1_007300 COC(=O)c1cc(no1)c2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L19 compound treatment 75880.0 -8020.0 -0.46 59360.0 -14300.0 -1.08 -1.0931 -0.929 1270867 TimTec1_007301 CCCC(CCC)C(=O)NC1CCN(Cc2ccccc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L20 compound treatment 73400.0 -10500.0 -0.61 62720.0 -10900.0 -0.83 -1.0148 -0.9887 3212864 TimTec1_007302 OC(=O)CN1C(=O)CSc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L21 compound treatment 79080.0 -4820.0 -0.28 63680.0 -9960.0 -0.75 -0.7308 -0.9088 1632361 TimTec1_007303 CC(=O)Nc1cccc(c1)C(=O)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L22 compound treatment 80320.0 -3580.0 -0.21 65680.0 -7960.0 -0.6 -0.5729 -0.8989 3087188 TimTec1_007304 Nc1nc2ccc(CC(=O)O)cc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L23 mock treatment 75040.0 -8860.0 -0.51 66240.0 -7400.0 -0.56 -0.7592 -0.9991 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 L24 mock treatment 81520.0 -2380.0 -0.14 64600.0 -9040.0 -0.68 -0.5815 -0.8331 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M01 compound treatment 16200.0 -67700.0 -3.92 8880.0 -64800.0 -4.9 -6.2399 -0.9939 3211168 TimTec1_007305 Brc1ccc(N/C=C\2/Sc3ccccc3C2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M02 compound treatment 82520.0 -1380.0 -0.08 72840.0 -800.0 -0.06 -0.0995 -0.9904 3087189 TimTec1_007306 Clc1ccc2nc(nc(c3ccccc3)c2c1)n4nc5ccccc5n4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M03 compound treatment 76520.0 -7380.0 -0.43 62320.0 -11300.0 -0.86 -0.9084 -0.9485 1413726 TimTec1_007307 CC1CCN(CC1)C(=O)C2CCN(CC3CCCCC3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M04 compound treatment 32200.0 -51700.0 -3.0 33680.0 -40000.0 -3.02 -4.2571 -1.0 3087190 TimTec1_007308 O=C(CCC1CCCC1)N2CCN(CC3CCC=CC3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M05 compound treatment 52040.0 -31900.0 -1.85 36320.0 -37300.0 -2.82 -3.3029 -0.9787 3211169 TimTec1_007309 Cc1cc2nn(nc2cc1NC(=O)c3cccs3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M06 compound treatment 75840.0 -8060.0 -0.47 67400.0 -6240.0 -0.47 -0.6644 -1.0 1787986 TimTec1_007310 CC1(C)CC(CC(C)(C)N1)NC(=O)c2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M07 compound treatment 31840.0 -52100.0 -3.02 26000.0 -47600.0 -3.61 -4.6829 -0.9961 1163680 TimTec1_007311 O=C1C(=C(C#N)c2nc3ccccc3[nH]2)C(=O)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M08 compound treatment 51120.0 -32800.0 -1.9 47480.0 -26200.0 -1.98 -2.7433 -0.9998 1392143 TimTec1_007312 CC(C)C(=O)Nc1nc2ccc(cc2s1)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M09 compound treatment 24840.0 -59100.0 -3.42 32600.0 -41000.0 -3.11 -4.6164 -0.9988 1649591 TimTec1_007313 COc1ccccc1N2CCN(Cc3ccc(SC)cc3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M10 compound treatment 55000.0 -28900.0 -1.67 57480.0 -16200.0 -1.22 -2.0491 -0.9881 1308504 TimTec1_007314 CN(C)C(=O)COc1ccc2c(C)cc(=O)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M11 compound treatment 53960.0 -29900.0 -1.73 53240.0 -20400.0 -1.54 -2.3187 -0.9983 1709084 TimTec1_007315 Cc1ccc(cc1)C2C3=C(CC(C)(C)CC3=O)OC4=C2C(=O)CC(C)(C)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M12 compound treatment 61240.0 -22700.0 -1.31 57680.0 -16000.0 -1.21 -1.7828 -0.9991 3087191 TimTec1_007316 CN(C)CCCNc1ncnc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M13 compound treatment 63360.0 -20500.0 -1.19 57200.0 -16400.0 -1.24 -1.7216 -0.9998 3211170 TimTec1_007317 CN(Cc1c(C)nn(C)c1C)C(=O)c2cnn3C(CC(Nc23)c4ccccc4)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M14 compound treatment 70800.0 -13100.0 -0.76 63680.0 -9960.0 -0.75 -1.07 -1.0 1229927 TimTec1_007318 O=C(NC1CS(=O)(=O)CC1NCc2ccco2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M15 compound treatment 72880.0 -11000.0 -0.64 60720.0 -12900.0 -0.98 -1.1432 -0.9787 1657371 TimTec1_007319 COc1ccc(CCN(C)CCC(=O)Nc2c(C)cc(C)cc2C)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M16 compound treatment 53680.0 -30200.0 -1.75 35840.0 -37800.0 -2.86 -3.2614 -0.9722 1600235 TimTec1_007320 COc1ccc(cc1)c2cc(c3ccco3)c(C#N)c(N)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M17 compound treatment 68480.0 -15400.0 -0.89 55280.0 -18400.0 -1.39 -1.6146 -0.9772 3087192 TimTec1_007321 Cc1sc2ncnc(SCC(=O)c3ccccc3)c2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M18 compound treatment 54960.0 -28900.0 -1.68 38080.0 -35600.0 -2.69 -3.0891 -0.9741 3211171 TimTec1_007322 Oc1ccccc1/C=N/c2ccccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M19 compound treatment 64200.0 -19700.0 -1.14 51760.0 -21900.0 -1.66 -1.9784 -0.9835 1238816 TimTec1_007323 NC1=C(C(=O)CN1C2CCCCC2)c3nc4ccccc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M20 compound treatment 74280.0 -9620.0 -0.56 64120.0 -9520.0 -0.72 -0.9038 -0.992 1918338 TimTec1_007324 CC1(C)CC(=O)C=C(C1)NCCCN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M21 compound treatment 39360.0 -44500.0 -2.58 34680.0 -39000.0 -2.95 -3.9102 -0.9978 1143746 TimTec1_007325 CC(=O)Nc1cc(nn1Cc2ccc(Cl)cc2)c3ccc(Br)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M22 compound treatment 62120.0 -21800.0 -1.26 61640.0 -12000.0 -0.91 -1.5348 -0.987 3211172 TimTec1_007326 CC(=C)CC(Nc1ccc(C)cc1)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M23 mock treatment 80840.0 -3060.0 -0.18 67840.0 -5800.0 -0.44 -0.436 -0.9206 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 M24 mock treatment 76200.0 -7700.0 -0.45 69320.0 -4320.0 -0.33 -0.5469 -0.9883 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N01 compound treatment 80640.0 -3260.0 -0.19 65480.0 -8160.0 -0.62 -0.5705 -0.8832 1282781 TimTec1_007327 OC(COCc1ccc2OCOc2c1)CN3CCN(CC3)c4ccc(F)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N02 compound treatment 81040.0 -2860.0 -0.17 60960.0 -12700.0 -0.96 -0.796 -0.8172 1422214 TimTec1_007328 OCCN1CCN(CC1)C(=O)CSc2nc3ccccc3c(=O)n2c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N03 compound treatment 67840.0 -16100.0 -0.93 57320.0 -16300.0 -1.24 -1.5316 -0.9903 3211173 TimTec1_007329 CC(C)OC(=O)CCc1nc2ccccc2nc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N04 compound treatment 66040.0 -17900.0 -1.04 52360.0 -21300.0 -1.61 -1.8709 -0.9771 1325424 TimTec1_007330 NS(=O)(=O)c1ccc(cc1)N2CCCC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N05 compound treatment 64760.0 -19100.0 -1.11 48040.0 -25600.0 -1.94 -2.1545 -0.965 1492718 TimTec1_007331 CCn1c(N)nc2n(C)c(=O)[nH]c(=O)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N06 compound treatment 69480.0 -14400.0 -0.84 56960.0 -16700.0 -1.26 -1.4837 -0.9799 1327606 TimTec1_007332 Cc1oc(c(CO)c1C(=O)O)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N07 compound treatment 57440.0 -26500.0 -1.53 56000.0 -17600.0 -1.34 -2.0284 -0.9976 3211174 TimTec1_007333 CC(C)C(=O)Nc1ccc(cc1)c2nc3cc(NC(=O)C(C)C)ccc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N08 compound treatment 55720.0 -28200.0 -1.63 56240.0 -17400.0 -1.32 -2.086 -0.9943 1130123 TimTec1_007334 Cc1ccc2nc(O)c(CCC(=O)O)c(C)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N09 compound treatment 48840.0 -35100.0 -2.03 51120.0 -22500.0 -1.7 -2.6419 -0.9962 1553061 TimTec1_007335 C(N1CCOCC1)c2nc3ccccc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N10 compound treatment 37720.0 -46200.0 -2.68 46160.0 -27500.0 -2.08 -3.3629 -0.9922 1761372 TimTec1_007336 Cc1ccc2cc(CN(Cc3ccccc3)C(=O)c4ccccc4C)c(=O)[nH]c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N11 compound treatment 55920.0 -28000.0 -1.62 58840.0 -14800.0 -1.12 -1.9386 -0.9837 1409640 TimTec1_007337 OC(=O)C1(CCC(=O)C1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N12 compound treatment 58960.0 -24900.0 -1.45 58040.0 -15600.0 -1.18 -1.8569 -0.995 3211175 TimTec1_007338 CC1(C)CC(CC(C)(C)N1)NCc2ccncc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N13 compound treatment 53240.0 -30700.0 -1.78 49400.0 -24200.0 -1.83 -2.5537 -0.9999 3211176 TimTec1_007339 COc1cccc(C(=O)N2CCN(Cc3ccccc3C(F)(F)F)CC2)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N14 compound treatment 65840.0 -18100.0 -1.05 55400.0 -18200.0 -1.38 -1.7163 -0.9907 3087193 TimTec1_007340 COC(=O)CN1C(=O)COc2ccc(C)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N15 compound treatment 31800.0 -52100.0 -3.02 17960.0 -55700.0 -4.21 -5.1148 -0.9866 1267449 TimTec1_007341 CC(C)Cc1ccc2c(N)c(sc2n1)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N16 compound treatment 61800.0 -22100.0 -1.28 45920.0 -27700.0 -2.1 -2.3893 -0.972 3211177 TimTec1_007342 Cc1cc(Cl)ccc1OCCCC(=O)Nc2ccccc2C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N17 compound treatment 72960.0 -10900.0 -0.63 48440.0 -25200.0 -1.91 -1.7972 -0.8941 1220509 TimTec1_007343 N(c1ccccc1)c2nc(Nc3ccccc3)nc(Oc4ccccc4)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N18 compound treatment 57560.0 -26300.0 -1.53 52440.0 -21200.0 -1.6 -2.214 -0.9997 1849790 TimTec1_007344 O=C(COC(=O)c1ccco1)NC2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N19 compound treatment 77520.0 -6380.0 -0.37 57800.0 -15800.0 -1.2 -1.1094 -0.8841 3087194 TimTec1_007345 O=S1(=O)C=C(N2CCOCC2)c3ccccc31 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N20 compound treatment 67440.0 -16500.0 -0.95 56320.0 -17300.0 -1.31 -1.6016 -0.9878 1673885 TimTec1_007346 COCC(C)NCc1cccc(Br)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N21 compound treatment 50080.0 -33800.0 -1.96 45040.0 -28600.0 -2.16 -2.9165 -0.9988 3211178 TimTec1_007347 O=C(CCCc1c[nH]c2ccccc12)N3CCCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N22 compound treatment 69880.0 -14000.0 -0.81 59000.0 -14600.0 -1.11 -1.3581 -0.9884 1139076 TimTec1_007348 CC1CC(c2ccccc2)n3ncnc3N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N23 mock treatment 68440.0 -15500.0 -0.9 64160.0 -9480.0 -0.72 -1.141 -0.9939 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 N24 mock treatment 70840.0 -13100.0 -0.76 65760.0 -7880.0 -0.6 -0.957 -0.993 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O01 compound treatment 34440.0 -49500.0 -2.87 26120.0 -47500.0 -3.6 -4.5699 -0.9937 1243484 TimTec1_007349 CC(C)C(=O)NC(c1ccc2cccnc2c1O)c3ccc(Cl)cc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O02 compound treatment 50480.0 -33400.0 -1.94 40800.0 -32800.0 -2.49 -3.1271 -0.9924 1718539 TimTec1_007350 O=C(CC1CCCCC1)Nc2ccc3OCCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O03 compound treatment 41240.0 -42700.0 -2.47 25920.0 -47700.0 -3.61 -4.3021 -0.9829 3211179 TimTec1_007351 COc1ccc(cc1)c2cc(n3ncc(C(=O)NC(C)(C)C)c3n2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O04 compound treatment 44280.0 -39600.0 -2.3 31120.0 -42500.0 -3.22 -3.8992 -0.9863 1737590 TimTec1_007352 COc1ccc(CN2CCN(Cc3cccc4ccccc34)CC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O05 compound treatment 69680.0 -14200.0 -0.82 55720.0 -17900.0 -1.36 -1.5419 -0.9715 3087195 TimTec1_007353 CC(NC(=O)C1C2CC(C)(NC1=O)Oc3ccccc23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O06 compound treatment 62840.0 -21100.0 -1.22 55720.0 -17900.0 -1.36 -1.8221 -0.9986 1548745 TimTec1_007354 CC(OC(=O)c1ccc(NC(=O)Cc2ccccc2)cc1)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O07 compound treatment 67080.0 -16800.0 -0.97 65960.0 -7680.0 -0.58 -1.1003 -0.9695 3087196 TimTec1_007355 CC(Sc1nc(C)cc(C)n1)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O08 compound treatment 42200.0 -41700.0 -2.42 54040.0 -19600.0 -1.48 -2.7576 -0.9726 3211180 TimTec1_007356 Cc1cc(=O)oc2[nH]nc(c3ccccc3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O09 compound treatment 57160.0 -26700.0 -1.55 62720.0 -10900.0 -0.83 -1.6802 -0.9567 1303989 TimTec1_007357 C(OC(CN1CCCC1)CN2CCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O10 compound treatment 50960.0 -32900.0 -1.91 55360.0 -18300.0 -1.38 -2.3281 -0.9875 1593421 TimTec1_007358 NC(=O)c1ccc2[nH]c3CCCCc3c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O11 compound treatment 58720.0 -25200.0 -1.46 53760.0 -19900.0 -1.5 -2.0958 -0.9999 3211181 TimTec1_007359 Nc1nc(NC(=O)c2ccco2)nn1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O12 compound treatment 80760.0 -3140.0 -0.18 62440.0 -11200.0 -0.85 -0.7283 -0.8399 1296021 TimTec1_007360 COc1ccc(cc1)C(=O)N2CCN(CC2)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O13 compound treatment 70680.0 -13200.0 -0.77 62200.0 -11400.0 -0.87 -1.1541 -0.9981 1153011 TimTec1_007361 CC1CCN(CC1)C(=O)CCCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O14 compound treatment 63640.0 -20300.0 -1.17 58720.0 -14900.0 -1.13 -1.6288 -0.9998 1079167 TimTec1_007362 CC1(C)CC(=O)C2=C(C1)OC3=C(C2c4ccccc4Cl)C(=O)CC(C)(C)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O15 compound treatment 68800.0 -15100.0 -0.88 54440.0 -19200.0 -1.45 -1.6465 -0.9705 1388332 TimTec1_007363 CNC(=O)c1c(O)c2ccccc2[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O16 compound treatment 20760.0 -63100.0 -3.66 21280.0 -52400.0 -3.96 -5.3894 -0.9992 3211244 TimTec1_007364 O/N=C/c1c(OCc2ccccc2)ccc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O17 compound treatment 58960.0 -24900.0 -1.45 46400.0 -27200.0 -2.06 -2.4799 -0.9849 1449392 TimTec1_007365 CCN(CC)c1ccc(CC(=O)NC(C)Cc2ccccc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O18 compound treatment 74880.0 -9020.0 -0.52 51080.0 -22600.0 -1.71 -1.5772 -0.8831 1229289 TimTec1_007366 CCc1ccc(cc1)C2C(=C(C)NC3=C2C(=O)CCC3)C(=O)Nc4ccccc4C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O19 compound treatment 62840.0 -21100.0 -1.22 54080.0 -19600.0 -1.48 -1.9099 -0.9954 1499628 TimTec1_007367 OC(CNc1nc2ccccc2s1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O20 compound treatment 62080.0 -21800.0 -1.26 56920.0 -16700.0 -1.27 -1.789 -1.0 1146614 TimTec1_007368 O=C(CC1CCCCC1)Nc2nc3ccccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O21 compound treatment 63160.0 -20700.0 -1.2 62560.0 -11100.0 -0.84 -1.4429 -0.9845 1429365 TimTec1_007369 CCOc1ccc(Nc2nc3c(C)cccc3cc2C#N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O22 compound treatment 72720.0 -11200.0 -0.65 67160.0 -6480.0 -0.49 -0.805 -0.9906 1134013 TimTec1_007370 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4cccc(F)c4)C(=O)CC(C)(C)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O23 mock treatment 75560.0 -8340.0 -0.48 68960.0 -4680.0 -0.35 -0.5924 -0.9883 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 O24 mock treatment 82600.0 -1300.0 -0.08 72760.0 -880.0 -0.07 -0.1005 -0.998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P01 compound treatment 88040.0 4140.0 0.24 78720.0 5080.0 0.38 0.4413 0.9741 1386295 TimTec1_007371 CC(C)(C)C(=O)N1CCN(Cc2ccccc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P02 compound treatment 18560.0 -65300.0 -3.79 11240.0 -62400.0 -4.72 -6.0169 -0.994 3087246 TimTec1_007372 O=C(CSc1ncnc2sc3CCCCc3c12)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P03 compound treatment 136040.0 52100.0 3.02 94880.0 21200.0 1.61 3.2727 0.9564 3087247 TimTec1_007373 Oc1cc(nn1c2nc3ccccc3s2)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P04 compound treatment 55640.0 -28300.0 -1.64 42520.0 -31100.0 -2.36 -2.8236 -0.9842 1158378 TimTec1_007374 O=C(C(c1ccccc1)c2ccccc2)N3CCc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P05 compound treatment 25720.0 -58200.0 -3.37 18800.0 -54800.0 -4.15 -5.319 -0.9947 1653550 TimTec1_007375 O=C(Cc1cccs1)Nc2nc3ccccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P06 compound treatment 33960.0 -49900.0 -2.89 35200.0 -38400.0 -2.91 -4.1036 -1.0 3211245 TimTec1_007376 CCOC(=O)COc1nc(cc(n1)C(F)(F)F)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P07 compound treatment 60200.0 -23700.0 -1.37 61840.0 -11800.0 -0.89 -1.6027 -0.9783 1544065 TimTec1_007377 COc1cc2CN(C)CC3(CCC(O)CC3)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P08 compound treatment 41320.0 -42600.0 -2.47 50960.0 -22700.0 -1.72 -2.9585 -0.9843 3211246 TimTec1_007378 Cc1nc(N)nc(C)c1Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P09 compound treatment 54320.0 -29600.0 -1.71 60160.0 -13500.0 -1.02 -1.9335 -0.9693 3087248 TimTec1_007379 COC(=O)Cn1nc(c2CCCCc21)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P10 compound treatment 54080.0 -29800.0 -1.73 53800.0 -19800.0 -1.5 -2.2838 -0.9976 3211247 TimTec1_007380 COC(=O)c1ccc(CN2CCN(Cc3ccc(o3)C(=O)OC)CC2)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P11 compound treatment 62240.0 -21700.0 -1.26 60120.0 -13500.0 -1.02 -1.6112 -0.9949 1443632 TimTec1_007381 Fc1ccc(OCC(=O)Nc2ccc(cc2)n3cnnn3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P12 compound treatment 15160.0 -68700.0 -3.98 20480.0 -53200.0 -4.02 -5.6617 -1.0 1599989 TimTec1_007382 COc1cc(cc(OC)c1OC)c2cc(C#N)on2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P13 compound treatment 6360.0 -77500.0 -4.49 6280.0 -67400.0 -5.1 -6.7822 -0.998 1535300 TimTec1_007383 CC1(O)N(CCc2cccc3ccccc23)C(=O)c4ccccc41 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P14 compound treatment 65440.0 -18500.0 -1.07 57360.0 -16300.0 -1.23 -1.6278 -0.9975 1782858 TimTec1_007384 CCC(C)(Nc1n[nH]c(=O)[nH]c1=O)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P15 compound treatment 80400.0 -3500.0 -0.2 65360.0 -8280.0 -0.63 -0.5868 -0.8906 1583688 TimTec1_007385 OC(=O)C1CCCc2c1[nH]c3ccc(Cl)cc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P16 compound treatment 66000.0 -17900.0 -1.04 60600.0 -13000.0 -0.99 -1.4315 -0.9997 1183239 TimTec1_007386 CC(C)c1nc2ccccc2n1CC(C)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P17 compound treatment 49000.0 -34900.0 -2.02 46320.0 -27300.0 -2.07 -2.8922 -0.9999 3211371 TimTec1_007387 O=C(CC1CC2CCC1C2)N(C(C(=O)NC3CCCCC3)c4cccs4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P18 compound treatment 63600.0 -20300.0 -1.18 63760.0 -9880.0 -0.75 -1.3607 -0.9761 1248349 TimTec1_007388 OC(=O)C1CCCN1C(=O)c2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P19 compound treatment 53800.0 -30100.0 -1.74 64680.0 -8960.0 -0.68 -1.7129 -0.9153 1705108 TimTec1_007389 CC(C)Oc1ccc(cc1)C(CC(=O)N)CC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P20 compound treatment 56880.0 -27000.0 -1.57 53000.0 -20600.0 -1.56 -2.2119 -1.0 1182227 TimTec1_007390 Clc1cccc(NCCC(=O)c2ccco2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P21 compound treatment 64320.0 -19600.0 -1.13 65200.0 -8440.0 -0.64 -1.2541 -0.9631 3211372 TimTec1_007391 CC1=CCC(C(C1)C(=O)NC2CCCCC2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P22 compound treatment 70960.0 -12900.0 -0.75 54600.0 -19000.0 -1.44 -1.5494 -0.9537 1251182 TimTec1_007392 COCC(C)NCc1cccc(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P23 mock treatment 63760.0 -20100.0 -1.17 60800.0 -12800.0 -0.97 -1.5125 -0.9959 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2083 P24 mock treatment 71200.0 -12700.0 -0.74 59920.0 -13700.0 -1.04 -1.2548 -0.9858 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A01 compound treatment 105120.0 30800.0 1.79 96160.0 16600.0 1.25 2.1486 0.985 3211373 TimTec1_007393 CC(C)C(=O)N1CCN(CC1)c2ccccc2N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A02 compound treatment 82960.0 8660.0 0.5 91480.0 11900.0 0.9 0.9902 0.962 1229675 TimTec1_007394 COc1ccccc1CC(=O)Nc2nncs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A03 compound treatment 84320.0 10000.0 0.58 74400.0 -5200.0 -0.39 0.1318 0.1879 3087249 TimTec1_007395 COc1cc2[nH]c(NC(=O)c3ccc(Cl)cc3)nc(=O)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A04 compound treatment 90320.0 16000.0 0.93 99080.0 19500.0 1.47 1.6986 0.9751 1648941 TimTec1_007396 CC(=O)Nc1ccccc1C(=O)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A05 compound treatment 84200.0 9900.0 0.57 90080.0 10500.0 0.79 0.9661 0.9873 3087250 TimTec1_007397 CN1CCC(CC1)OC(=O)c2cc3ccccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A06 compound treatment 59080.0 -15200.0 -0.88 74840.0 -4760.0 -0.36 -0.8787 -0.9221 3211374 TimTec1_007398 CCOc1ccc(cc1)C(=O)OCC(=O)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A07 compound treatment 89040.0 14700.0 0.85 93560.0 14000.0 1.06 1.3507 0.9944 1229195 TimTec1_007399 OC(=O)c1cc(NC(=O)Cc2ccccc2)ccc1N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A08 compound treatment 57760.0 -16500.0 -0.96 73040.0 -6560.0 -0.5 -1.0291 -0.9532 3087251 TimTec1_007400 CCc1ccc(OCC(=O)N2CCc3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A09 compound treatment 65920.0 -8390.0 -0.49 70600.0 -9000.0 -0.68 -0.8254 -0.9862 3211375 TimTec1_007401 CCNc1oc(COc2ccc(OC)cc2)nc1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A10 compound treatment 79520.0 5220.0 0.3 89760.0 10200.0 0.77 0.7573 0.9168 3087252 TimTec1_007402 COCc1[nH]nc2OC(=C(C#N)C3(C(=O)Nc4ccccc43)c12)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A11 compound treatment 71000.0 -3310.0 -0.19 68880.0 -10700.0 -0.81 -0.7094 -0.8506 3211376 TimTec1_007403 C=CCOc1ccccc1CNc2nc[nH]n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A12 compound treatment 59600.0 -14700.0 -0.85 60160.0 -19400.0 -1.47 -1.6431 -0.9662 3211377 TimTec1_007404 CN(C)c1oc(nc1C#N)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A13 compound treatment 78880.0 4580.0 0.27 85760.0 6160.0 0.47 0.5169 0.9642 3087253 TimTec1_007405 COc1cc(OC)cc(OCC(O)Cn2ccnc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A14 compound treatment 75200.0 895.0 0.05 81440.0 1840.0 0.14 0.1349 0.9097 3211378 TimTec1_007406 CC(Oc1ccccc1F)C(=O)NCc2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A15 compound treatment 75760.0 1460.0 0.08 88560.0 8960.0 0.68 0.539 0.789 3551464 TimTec1_007407 OC12CCCCC2C(NCC1)c3ccc(Cl)cc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A16 compound treatment 78400.0 4100.0 0.24 81440.0 1840.0 0.14 0.266 0.9675 1438511 TimTec1_007408 COc1cc(cc(OC)c1OC)C(=O)N2CCN(CC2)C(=O)Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A17 compound treatment 57120.0 -17200.0 -1.0 56280.0 -23300.0 -1.77 -1.9524 -0.9633 3211379 TimTec1_007409 CCn1nnc(NC(=O)c2sc3ccccc3c2Cl)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A18 compound treatment 67680.0 -6630.0 -0.38 75080.0 -4520.0 -0.34 -0.5135 -0.9984 3211380 TimTec1_007410 COc1cccc(NC(=O)Cn2c(nc3ccccc23)c4cncs4)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A19 compound treatment 81040.0 6740.0 0.39 72960.0 -6640.0 -0.5 -0.0797 -0.1252 3087254 TimTec1_007411 COC(=O)c1cn(CC(=O)NCc2ccc3OCOc3c2)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A20 compound treatment 85920.0 11600.0 0.67 88920.0 9320.0 0.71 0.9745 0.9997 3211381 TimTec1_007412 Cc1ccccc1C(=O)Nc2c(C)nc(O)nc2O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A21 compound treatment 79520.0 5220.0 0.3 88840.0 9240.0 0.7 0.708 0.9296 3087255 TimTec1_007413 Cc1sc2ncnc(N3CCN(CCO)CC3)c2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A22 compound treatment 58200.0 -16100.0 -0.93 65240.0 -14400.0 -1.09 -1.4286 -0.9971 1416150 TimTec1_007414 COc1cc(cc(OC)c1OC)C(=O)Oc2ccc(Cl)c3cccnc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A23 mock treatment 85120.0 10800.0 0.63 92320.0 12700.0 0.96 1.1237 0.9784 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 A24 mock treatment 92680.0 18400.0 1.06 92240.0 12600.0 0.96 1.4291 0.9986 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B01 compound treatment 6560.0 -67700.0 -3.92 7680.0 -71900.0 -5.44 -6.625 -0.9871 1286008 TimTec1_007415 Cc1nc(C)c(s1)c2csc(Nc3cccc(C)c3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B02 compound treatment 52840.0 -21500.0 -1.24 67880.0 -11700.0 -0.89 -1.5069 -0.9863 3211382 TimTec1_007416 Clc1ccc(cc1)C2SC(=O)NC3=C2C(=O)c4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B03 compound treatment 60440.0 -13900.0 -0.8 78680.0 -924.0 -0.07 -0.6175 -0.7658 1624823 TimTec1_007417 CN1CCN(Cc2ccc(O)c3ncccc23)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B04 compound treatment 81200.0 6900.0 0.4 92400.0 12800.0 0.97 0.9674 0.9233 1292705 TimTec1_007418 COc1ccc(CC(=O)Nc2cc(C)on2)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B05 compound treatment 50200.0 -24100.0 -1.4 60560.0 -19000.0 -1.44 -2.0068 -0.9999 3087256 TimTec1_007419 Cc1occc1C(=O)Nc2ccc(OCc3ccccc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B06 compound treatment 79320.0 5020.0 0.29 83000.0 3400.0 0.26 0.3872 0.9981 1651373 TimTec1_007420 COc1ccc(cc1)N2CC(CC2=O)C(=O)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B07 compound treatment 77440.0 3140.0 0.18 89360.0 9760.0 0.74 0.6506 0.8555 3211383 TimTec1_007421 CC(Oc1ccc(Cl)cc1Cl)C(=O)NCCN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B08 compound treatment 4880.0 -69400.0 -4.02 10800.0 -68800.0 -5.21 -6.5269 -0.9918 3087257 TimTec1_007422 CCC(=O)Nc1nc2ccc(C)cc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B09 compound treatment 75200.0 895.0 0.05 88480.0 8880.0 0.67 0.5118 0.7594 3211384 TimTec1_007423 CCOc1ccc(cc1)C(=O)N2CCC(CC2)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B10 compound treatment 71840.0 -2470.0 -0.14 88160.0 8560.0 0.65 0.357 0.5383 3087258 TimTec1_007424 CN(C1CCCCC1)c2c[nH]c(=O)[nH]c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B11 compound treatment 86160.0 11900.0 0.69 94240.0 14600.0 1.11 1.2691 0.9736 3211385 TimTec1_007425 O=C(Cc1ccccc1)NCCN2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B12 compound treatment 95880.0 21600.0 1.25 93840.0 14200.0 1.08 1.6459 0.9973 1417865 TimTec1_007426 CC(C)C(=O)Nc1scc(c1C(=O)O)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B13 compound treatment 58640.0 -15700.0 -0.91 77080.0 -2520.0 -0.19 -0.7768 -0.8376 1861875 TimTec1_007427 O=C(Nc1ccccc1N2CCCC2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B14 compound treatment 55240.0 -19100.0 -1.1 68480.0 -11100.0 -0.84 -1.3764 -0.991 3087259 TimTec1_007428 C=CCn1c(nc2ccccc12)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B15 compound treatment 78280.0 3980.0 0.23 92000.0 12400.0 0.94 0.8263 0.8553 3211460 TimTec1_007429 CC(C)c1ccc(NC(=O)C2CC(=O)N=C(N)S2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B16 compound treatment 67640.0 -6670.0 -0.39 78160.0 -1440.0 -0.11 -0.3503 -0.8729 3211461 TimTec1_007430 C(Oc1cccc2ccccc12)c3nc(no3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B17 compound treatment 63600.0 -10700.0 -0.62 77240.0 -2360.0 -0.18 -0.5651 -0.8754 3087260 TimTec1_007431 CCN(C(=O)Cn1cc(C(=O)C2CC2)c3ccccc13)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B18 compound treatment 78760.0 4460.0 0.26 95000.0 15400.0 1.17 1.0066 0.8433 1228419 TimTec1_007432 COc1ccccc1Nc2nc(c3ccccc3)c4cc(Cl)ccc4n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B19 compound treatment 75960.0 1660.0 0.1 91240.0 11600.0 0.88 0.6906 0.7795 1437567 TimTec1_007433 CC(C)c1ccc(NC2(C#N)C(=O)Nc3ccccc32)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B20 compound treatment 83480.0 9180.0 0.53 96120.0 16500.0 1.25 1.2599 0.9274 3211462 TimTec1_007434 CC1=C(C)CC(C(C1)C(=O)O)C(=O)Nc2cccc(C)c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B21 compound treatment 83320.0 9020.0 0.52 87800.0 8200.0 0.62 0.808 0.9963 3211463 TimTec1_007435 Cc1nc(NC2=NCCC(=O)N2)nc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B22 compound treatment 70120.0 -4190.0 -0.24 69040.0 -10600.0 -0.8 -0.7369 -0.8819 1158692 TimTec1_007436 CC(C)NC(=O)c1ccc2ccccc2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B23 mock treatment 82120.0 7820.0 0.45 92600.0 13000.0 0.98 1.0158 0.938 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 B24 mock treatment 80520.0 6220.0 0.36 95720.0 16100.0 1.22 1.1172 0.8784 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C01 compound treatment 48640.0 -25700.0 -1.49 63880.0 -15700.0 -1.19 -1.893 -0.9939 3211464 TimTec1_007437 COc1ccc(cc1)c2nc(O)c3ccccc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C02 compound treatment 72840.0 -1470.0 -0.08 83240.0 3640.0 0.28 0.1346 0.4673 1154391 TimTec1_007438 CCOc1ccccc1C(=O)Nc2nc3ccc(cc3s2)S(=O)(=O)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C03 compound treatment 77600.0 3300.0 0.19 87600.0 8000.0 0.61 0.563 0.8871 3211465 TimTec1_007439 Cc1ccc2nc(Nc3nccc(C)n3)nc(C)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C04 compound treatment 66320.0 -7990.0 -0.46 75240.0 -4360.0 -0.33 -0.5607 -0.9864 3087261 TimTec1_007440 Cc1nc2ccccc2c(=O)n1c3nc4ccccc4n3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C05 compound treatment 75160.0 855.0 0.05 79720.0 116.0 0.01 0.0412 0.8199 3211466 TimTec1_007441 CN1CCC(CC1)OC(=O)c2ccc3OCCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C06 compound treatment 83640.0 9340.0 0.54 92320.0 12700.0 0.96 1.0631 0.9628 3211467 TimTec1_007442 COCc1nnc(NC(=O)Cc2ccccc2)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C07 compound treatment 76400.0 2100.0 0.12 87200.0 7600.0 0.57 0.4924 0.8379 3211468 TimTec1_007443 OC(=O)C1CCCCC1C(=O)Nc2ccc(cc2)C(=O)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C08 compound treatment 53280.0 -21000.0 -1.22 74000.0 -5600.0 -0.42 -1.1613 -0.9003 3087262 TimTec1_007444 Cc1cccc(C)c1OCC(=O)N2CCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C09 compound treatment 83320.0 9020.0 0.52 87080.0 7480.0 0.57 0.7695 0.9992 1195541 TimTec1_007445 CCN(CC)CCCN1C(C(=C(O)C1=O)C(=O)c2cc(C)ccc2C)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C10 compound treatment 76520.0 2220.0 0.13 90920.0 11300.0 0.86 0.6964 0.8041 1658976 TimTec1_007446 OC(=O)C1CCCCC1C(=O)Nc2cccc(F)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C11 compound treatment 66520.0 -7790.0 -0.45 80520.0 916.0 0.07 -0.2699 -0.5914 3211469 TimTec1_007447 COC(=O)c1cn(CC(=O)N2CCCCC2C)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C12 compound treatment 64640.0 -9670.0 -0.56 76280.0 -3320.0 -0.25 -0.5739 -0.9348 1699768 TimTec1_007448 Cc1ccc(cc1)S(=O)(=O)c2nc(sc2Cl)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C13 compound treatment 77000.0 2700.0 0.16 92880.0 13300.0 1.0 0.821 0.8073 3211470 TimTec1_007449 CCc1cccc2c(C#N)cn(CC(=O)NC3CCCC3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C14 compound treatment 79840.0 5540.0 0.32 85240.0 5640.0 0.43 0.5284 0.9901 3087263 TimTec1_007450 Cc1ccc(C)c(c1)C(=O)C2=C(O)C(=O)N(CCCn3ccnc3)C2c4cccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C15 compound treatment 59480.0 -14800.0 -0.86 76760.0 -2840.0 -0.22 -0.7596 -0.8578 3087311 TimTec1_007451 COc1ccccc1N2CCN(CC2)C(=O)CC(C)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C16 compound treatment 76000.0 1700.0 0.1 87800.0 8200.0 0.62 0.5081 0.809 1347933 TimTec1_007452 Clc1cccc(CN2CCN(Cc3ccco3)CC2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C17 compound treatment 60680.0 -13600.0 -0.79 71040.0 -8560.0 -0.65 -1.0166 -0.9952 3087312 TimTec1_007453 CC(Oc1ccc(Cl)cc1Cl)C(=O)NCCCn2ccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C18 compound treatment 38120.0 -36200.0 -2.1 57560.0 -22000.0 -1.67 -2.6623 -0.9936 3087313 TimTec1_007454 Cc1ccccc1Cn2c(nc3ccccc23)c4cncs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C19 compound treatment 73040.0 -1270.0 -0.07 83000.0 3400.0 0.26 0.13 0.4861 3087314 TimTec1_007455 Nc1[nH]c(SCC(=O)N2CCCC2)nc(=O)c1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C20 compound treatment 76920.0 2620.0 0.15 87760.0 8160.0 0.62 0.5437 0.8553 3087315 TimTec1_007456 FC(F)(F)c1nc2cc3[nH]c(=O)[nH]c3cc2[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C21 compound treatment 34760.0 -39500.0 -2.29 51920.0 -27700.0 -2.1 -3.1018 -0.999 3087316 TimTec1_007457 CCc1cc2c(NCC3CCCO3)nc(C)nc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C22 compound treatment 85920.0 11600.0 0.67 90880.0 11300.0 0.85 1.0794 0.9931 3087317 TimTec1_007458 Cc1ccc(C)c(OCCCN2CCNCC2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C23 mock treatment 79640.0 5340.0 0.31 82080.0 2480.0 0.19 0.3511 0.9713 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 C24 mock treatment 82600.0 8300.0 0.48 86480.0 6880.0 0.52 0.7079 0.9992 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D01 compound treatment 68480.0 -5830.0 -0.34 67800.0 -11800.0 -0.89 -0.8704 -0.9114 3211471 TimTec1_007459 COC(=O)C1=C(C)OC(=C(C#N)C1c2ccc(cc2)C(=O)OC)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D02 compound treatment 25760.0 -48500.0 -2.81 27240.0 -52400.0 -3.96 -4.7915 -0.9859 3087318 TimTec1_007460 Cc1ccnc(Nc2nc3ccccc3s2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D03 compound treatment 59720.0 -14600.0 -0.85 77040.0 -2560.0 -0.19 -0.7347 -0.8474 3211472 TimTec1_007461 Cc1cccn2cc(CNc3nc4ccccc4s3)nc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D04 compound treatment 30960.0 -43300.0 -2.51 51080.0 -28500.0 -2.16 -3.3025 -0.9972 3211473 TimTec1_007462 OCc1nc2ccccc2n1C/C=C/c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D05 compound treatment 64560.0 -9750.0 -0.56 71480.0 -8120.0 -0.61 -0.8341 -0.9991 3087319 TimTec1_007463 COC(=O)c1cn(C(=O)COc2ccccc2Cl)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D06 compound treatment 67360.0 -6950.0 -0.4 90480.0 10900.0 0.82 0.2976 0.3248 3211474 TimTec1_007464 COC(=O)CNc1ccc2OCOc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D07 compound treatment 62040.0 -12300.0 -0.71 78240.0 -1360.0 -0.1 -0.5755 -0.8014 3087320 TimTec1_007465 Cc1cc(C)c(C)c(OCC(=O)NCC2CCCO2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D08 compound treatment 67320.0 -6990.0 -0.4 81080.0 1480.0 0.11 -0.2071 -0.4934 1236869 TimTec1_007466 CC(C)N1CC(CC1=O)C(=O)Nc2ccc(Cl)c(Cl)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D09 compound treatment 69240.0 -5070.0 -0.29 81240.0 1640.0 0.12 -0.1199 -0.3765 3087321 TimTec1_007467 C1Oc2ccc(cc2O1)c3nc(no3)c4cccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D10 compound treatment 55640.0 -18700.0 -1.08 72960.0 -6640.0 -0.5 -1.1203 -0.9393 1259602 TimTec1_007468 CCCn1c(nc2ccccc12)C(=O)c3ccc(OC)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D11 compound treatment 61360.0 -12900.0 -0.75 75160.0 -4440.0 -0.34 -0.7682 -0.9346 3211475 TimTec1_007469 Cc1ccccc1OCC(=O)Nc2ncccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D12 compound treatment 53520.0 -20800.0 -1.2 75560.0 -4040.0 -0.31 -1.068 -0.8595 1684343 TimTec1_007470 O=c1n(cnc2scc(c3cccs3)c12)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D13 compound treatment 69960.0 -4350.0 -0.25 81640.0 2040.0 0.15 -0.069 -0.2338 1861864 TimTec1_007471 CCC(=O)Nc1ccccc1N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D14 compound treatment 74160.0 -145.0 -0.01 81600.0 2000.0 0.15 0.1009 0.6668 3087322 TimTec1_007472 CC(C)C(=O)NCCc1nc2ccccc2[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D15 compound treatment 78480.0 4180.0 0.24 77520.0 -2080.0 -0.16 0.0595 0.2061 3211476 TimTec1_007473 COc1cc(ccc1OCC(=O)N)C2NC(=O)NC(=C2C(=O)NCc3ccccc3)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D16 compound treatment 72640.0 -1670.0 -0.1 81360.0 1760.0 0.13 0.0258 0.157 3087323 TimTec1_007474 Cc1cc(=O)[nH]c(n1)N2CCN(Cc3ccccc3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D17 compound treatment 71120.0 -3190.0 -0.18 75720.0 -3880.0 -0.29 -0.3384 -0.9748 3211477 TimTec1_007475 COc1ccc(OCC(=O)Nc2ccccc2C(=O)N3CCOCC3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D18 compound treatment 66080.0 -8230.0 -0.48 83040.0 3440.0 0.26 -0.153 -0.2819 1603028 TimTec1_007476 Brc1ccc2nc(nc(c3ccccc3)c2c1)N4CCN(CC4)C(=O)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D19 compound treatment 66960.0 -7350.0 -0.43 83960.0 4360.0 0.33 -0.0677 -0.1258 1256546 TimTec1_007477 CCOC(=O)c1sc(NC=O)c(C(=O)OCC)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D20 compound treatment 78240.0 3940.0 0.23 82480.0 2880.0 0.22 0.3152 0.9997 1296988 TimTec1_007478 Clc1ccc(cc1Cl)C(=O)COC(=O)CCn2nnc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D21 compound treatment 73000.0 -1310.0 -0.08 86880.0 7280.0 0.55 0.336 0.6044 3087324 TimTec1_007479 COCc1cc(O)nc(Nc2nc3ccccc3s2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D22 compound treatment 67440.0 -6870.0 -0.4 76120.0 -3480.0 -0.26 -0.4677 -0.9801 3211478 TimTec1_007480 CC(C)C(=O)Nc1cnc2ccccc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D23 mock treatment 79440.0 5140.0 0.3 86600.0 7000.0 0.53 0.5848 0.9628 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 D24 mock treatment 80240.0 5940.0 0.34 83720.0 4120.0 0.31 0.4635 0.9988 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E01 compound treatment 79440.0 5140.0 0.3 85680.0 6080.0 0.46 0.5356 0.9778 3087325 TimTec1_007481 Cc1cc(C)nc(NC(=N)N2N=CCC2c3ccccc3)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E02 compound treatment 77760.0 3460.0 0.2 77680.0 -1920.0 -0.15 0.0386 0.1558 3211479 TimTec1_007482 CCC(CC)c1nnc(NC(=O)c2c(OC)cccc2OC)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E03 compound treatment 70600.0 -3710.0 -0.21 77160.0 -2440.0 -0.18 -0.2826 -0.9973 3211480 TimTec1_007483 C(CN1CNC(=NC1)Nc2nc3ccccc3s2)N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E04 compound treatment 78320.0 4020.0 0.23 78440.0 -1160.0 -0.09 0.1022 0.4109 1489932 TimTec1_007484 CC1(C)Cc2c(C#N)c(NC(=O)c3ccccc3)sc2C(C)(C)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E05 compound treatment 70640.0 -3670.0 -0.21 78480.0 -1120.0 -0.09 -0.2103 -0.9193 1191967 TimTec1_007485 CCCc1c(C)nc2c(OC)cccc2c1SCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E06 compound treatment 41040.0 -33300.0 -1.93 61640.0 -18000.0 -1.36 -2.3243 -0.9854 3087326 TimTec1_007486 COc1cccc(=O)c2c(C)n(C)c(C)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E07 compound treatment 71720.0 -2590.0 -0.15 76680.0 -2920.0 -0.22 -0.2624 -0.9819 3211481 TimTec1_007487 COc1ccc(cc1)C(=O)OCc2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E08 compound treatment 64480.0 -9830.0 -0.57 83080.0 3480.0 0.26 -0.2164 -0.3452 3087327 TimTec1_007488 CCC(CC)C(=O)N1CCN(CC1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E09 compound treatment 75240.0 935.0 0.05 89360.0 9760.0 0.74 0.5605 0.7569 3211554 TimTec1_007489 Cc1ccc(o1)C(=O)C2=C(O)C(=O)N(C2c3cccc(OCC=C)c3)c4nnc(C)s4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E10 compound treatment 75440.0 1140.0 0.07 90360.0 10800.0 0.81 0.6222 0.7617 3087328 TimTec1_007490 CCN(CC)Cc1cc(oc1C(=O)O)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E11 compound treatment 54080.0 -20200.0 -1.17 63960.0 -15600.0 -1.18 -1.6659 -1.0 3211555 TimTec1_007491 Cc1ccc(OCCCn2c(=O)oc3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E12 compound treatment 64080.0 -10200.0 -0.59 78360.0 -1240.0 -0.09 -0.4855 -0.8093 1870617 TimTec1_007492 Cc1nc(NC(=O)c2sc3ccccc3c2Cl)sc1C(=O)OCC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E13 compound treatment 26640.0 -47700.0 -2.76 50680.0 -28900.0 -2.19 -3.5009 -0.9934 3087329 TimTec1_007493 COC(=O)c1cn(CCCOc2ccccc2OC)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E14 compound treatment 53920.0 -20400.0 -1.18 67120.0 -12500.0 -0.94 -1.5033 -0.9939 1875124 TimTec1_007494 COc1ccc(CNC(=O)c2oc3ccccc3c2C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E15 compound treatment 63960.0 -10300.0 -0.6 77000.0 -2600.0 -0.2 -0.5632 -0.8926 3087330 TimTec1_007495 CCOCC(=O)N1CCN(CC1)c2cccc(C)c2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E16 compound treatment 72240.0 -2070.0 -0.12 83320.0 3720.0 0.28 0.1143 0.3739 1718923 TimTec1_007496 C(N1CCN(CC1)C2CCCCCC2)c3ccc4OCOc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E17 compound treatment 71560.0 -2750.0 -0.16 80720.0 1120.0 0.08 -0.0527 -0.2927 1863832 TimTec1_007497 CC(C)(C)NCc1ccccc1OCc2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E18 compound treatment 43640.0 -30700.0 -1.78 59560.0 -20000.0 -1.52 -2.3291 -0.9969 3211556 TimTec1_007498 S(C(c1ccccc1)c2ccccc2)c3nc[nH]n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E19 compound treatment 67000.0 -7310.0 -0.42 74480.0 -5120.0 -0.39 -0.5735 -0.999 3211557 TimTec1_007499 COC(=O)c1cn(CC(=O)NCc2ccco2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E20 compound treatment 62800.0 -11500.0 -0.67 79520.0 -83.8 -0.01 -0.4758 -0.7138 3087331 TimTec1_007500 C(NC(c1ccccc1)c2ccccc2)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E21 compound treatment 4200.0 -70100.0 -4.06 5720.0 -73900.0 -5.59 -6.8266 -0.9877 3087332 TimTec1_007501 C1CCC(C1)Nc2ncnc3sc4CCCc4c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E22 compound treatment 46320.0 -28000.0 -1.62 58080.0 -21500.0 -1.63 -2.2985 -1.0 1600198 TimTec1_007502 Clc1cc(NCc2ccc3OCOc3c2)ccc1N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E23 mock treatment 76760.0 2460.0 0.14 81920.0 2320.0 0.18 0.2246 0.9946 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 E24 mock treatment 78840.0 4540.0 0.26 77800.0 -1800.0 -0.14 0.0892 0.3014 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F01 compound treatment 78880.0 4580.0 0.27 80840.0 1240.0 0.09 0.2536 0.9022 3211558 TimTec1_007503 CN(C)C(=O)C1=C(C)NC(=O)NC1c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F02 compound treatment 76080.0 1780.0 0.1 82120.0 2520.0 0.19 0.2074 0.9582 3087333 TimTec1_007504 Cc1cc(C)nc(NC2=NC(=O)CC(N2c3cccc(Cl)c3)C(=O)O)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F03 compound treatment 60040.0 -14300.0 -0.83 70000.0 -9600.0 -0.73 -1.0984 -0.998 1348377 TimTec1_007505 Cc1cc(C)c(C#N)c(SCC(O)COc2ccc(Cl)cc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F04 compound treatment 49480.0 -24800.0 -1.44 66520.0 -13100.0 -0.99 -1.7173 -0.9834 3087334 TimTec1_007506 CC(=C)Cn1c(Cc2ccccc2)nc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F05 compound treatment 72680.0 -1630.0 -0.09 84000.0 4400.0 0.33 0.1687 0.4879 1458633 TimTec1_007507 Clc1ccc(CC(=O)N2CCN(CC2)C=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F06 compound treatment 71880.0 -2430.0 -0.14 81200.0 1600.0 0.12 -0.0139 -0.0751 3211559 TimTec1_007508 C=CCNC(=O)C1CN(C(=O)C1)c2ccc(OCC(=O)N3CCCC3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F07 compound treatment 70800.0 -3510.0 -0.2 80240.0 636.0 0.05 -0.1095 -0.5249 3087335 TimTec1_007509 CC(C)N(C(C)C)C(=O)Cc1cccs1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F08 compound treatment 77760.0 3460.0 0.2 85400.0 5800.0 0.44 0.4518 0.9368 1336201 TimTec1_007510 Oc1c(CN2CCCC2)c(=O)oc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F09 compound treatment 37800.0 -36500.0 -2.12 31640.0 -48000.0 -3.63 -4.0628 -0.9669 3211560 TimTec1_007511 Cc1cc(C)c2c(n1)sc3c4OC(=C(C#N)C(c5cccc(Cl)c5)c4c(=O)[nH]c32)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F10 compound treatment 76920.0 2620.0 0.15 83640.0 4040.0 0.31 0.3232 0.9476 3087336 TimTec1_007512 CCC(=O)Nc1ccc2n(cnc2c1)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F11 compound treatment 73960.0 -345.0 -0.02 82680.0 3080.0 0.23 0.1505 0.644 3087337 TimTec1_007513 Fc1ccc(OCC(=O)NCCN2CCOCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F12 compound treatment 70640.0 -3670.0 -0.21 87640.0 8040.0 0.61 0.28 0.4346 1313563 TimTec1_007514 CC(C)(C)C(=O)Nc1scc(c2cccs2)c1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F13 compound treatment 16840.0 -57500.0 -3.33 24720.0 -54900.0 -4.15 -5.2918 -0.994 1443986 TimTec1_007515 CCC(=O)Nc1nc2ccc(OC)cc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F14 compound treatment 71640.0 -2670.0 -0.15 84400.0 4800.0 0.36 0.1475 0.374 1708556 TimTec1_007516 OC(=O)CC1(O)C(=O)N(Cc2ccccc2)c3ccccc31 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F15 compound treatment 68160.0 -6150.0 -0.36 84040.0 4440.0 0.34 -0.0143 -0.0292 3211561 TimTec1_007517 CCc1ccc(NC2OC(=O)c3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F16 compound treatment 73440.0 -865.0 -0.05 75760.0 -3840.0 -0.29 -0.2412 -0.8169 1594430 TimTec1_007518 COc1ccc(OCC(=O)N2CCN(CC2)c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F17 compound treatment 67800.0 -6510.0 -0.38 83800.0 4200.0 0.32 -0.0419 -0.085 3211562 TimTec1_007519 CC(N(c1ccccc1)S(=O)(=O)C)C(=O)N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F18 compound treatment 56320.0 -18000.0 -1.04 61320.0 -18300.0 -1.38 -1.7154 -0.9902 1461764 TimTec1_007520 Brc1ccc2nc(Nc3ccc(cc3)C(=O)N4CCOCC4)nc(c5ccccc5)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F19 compound treatment 75720.0 1420.0 0.08 78720.0 -884.0 -0.07 0.0107 0.1008 3087338 TimTec1_007521 CC(C)(C)c1ccc(cc1)C(=O)n2cnnc2N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F20 compound treatment 71840.0 -2470.0 -0.14 86120.0 6520.0 0.49 0.2478 0.4825 1738860 TimTec1_007522 Clc1ccc(cc1)C(=O)COC(=O)c2cnccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F21 compound treatment 24600.0 -49700.0 -2.88 39000.0 -40600.0 -3.07 -4.2096 -0.9995 3211563 TimTec1_007523 CCN(C(=O)c1ccc(Cl)cc1Cl)c2nnc(s2)c3ccncc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F22 compound treatment 73040.0 -1270.0 -0.07 82760.0 3160.0 0.24 0.1171 0.4686 1155556 TimTec1_007524 CC(C)C(=O)Nc1ccc2OCCOc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F23 mock treatment 79800.0 5500.0 0.32 84120.0 4520.0 0.34 0.4668 0.9994 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 F24 mock treatment 76760.0 2460.0 0.14 90200.0 10600.0 0.8 0.6677 0.8197 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G01 compound treatment 20720.0 -53600.0 -3.1 21920.0 -57700.0 -4.37 -5.2827 -0.986 3211564 TimTec1_007525 O=C(NC1=NC2CCCCC2N1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G02 compound treatment 75320.0 1020.0 0.06 81880.0 2280.0 0.17 0.1634 0.8976 3211565 TimTec1_007526 CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc2nncs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G03 compound treatment 67520.0 -6790.0 -0.39 79280.0 -324.0 -0.02 -0.2953 -0.7497 3087339 TimTec1_007527 COC(=O)CC1=C(C(NC(=O)N1)c2ccccc2)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G04 compound treatment 62880.0 -11400.0 -0.66 74200.0 -5400.0 -0.41 -0.7573 -0.9732 1183771 TimTec1_007528 Cc1ccc(OCC(=O)Nc2sc3c(CC(C)(C)NC3(C)C)c2C#N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G05 compound treatment 69440.0 -4870.0 -0.28 85960.0 6360.0 0.48 0.1409 0.2527 3211566 TimTec1_007529 CC1CCCC(C1)NCCNC(=O)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G06 compound treatment 63200.0 -11100.0 -0.64 75160.0 -4440.0 -0.34 -0.6928 -0.9542 1176872 TimTec1_007530 O=C(Nc1ncnc2sc3CCCCCc3c12)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G07 compound treatment 61840.0 -12500.0 -0.72 76760.0 -2840.0 -0.22 -0.6629 -0.8796 3211567 TimTec1_007531 Cc1nn(C2CCCC2)c3[nH]c(=O)cc(C)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G08 compound treatment 67800.0 -6510.0 -0.38 80120.0 516.0 0.04 -0.2389 -0.6304 1382217 TimTec1_007532 Nc1ccc2n(CCO)c(CO)nc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G09 compound treatment 71520.0 -2790.0 -0.16 77200.0 -2400.0 -0.18 -0.2428 -0.9982 1564264 TimTec1_007533 Cc1oc(cc1COc2ccc(C)cc2)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G10 compound treatment 60200.0 -14100.0 -0.82 74360.0 -5240.0 -0.4 -0.8585 -0.945 3211568 TimTec1_007534 Clc1ccc(NC(=O)C2CN(C3CCCCC3)C(=O)C2)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G11 compound treatment 45560.0 -28700.0 -1.67 59600.0 -20000.0 -1.51 -2.2483 -0.9989 3087380 TimTec1_007535 CC(C)C(=O)Nc1ncc(Cc2ccccc2Cl)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G12 compound treatment 68040.0 -6270.0 -0.36 72160.0 -7440.0 -0.56 -0.6551 -0.9774 3087381 TimTec1_007536 CN(C)CCN1C(C(=C(O)C1=O)C(=O)c2ccccc2)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G13 compound treatment 67480.0 -6830.0 -0.4 74720.0 -4880.0 -0.37 -0.541 -0.9994 3087382 TimTec1_007537 OC(=O)C1C(C2CC1C=C2)C(=O)NCCc3ccncc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G14 compound treatment 50760.0 -23500.0 -1.36 69840.0 -9760.0 -0.74 -1.4872 -0.9586 3087383 TimTec1_007538 O=C(Nc1sc2CCCc2c1C(=O)NCc3ccco3)C4COc5ccccc5O4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G15 compound treatment 51240.0 -23100.0 -1.34 56040.0 -23600.0 -1.78 -2.2062 -0.9899 3087384 TimTec1_007539 C1CCC(CC1)c2noc(n2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G16 compound treatment 72680.0 -1630.0 -0.09 82120.0 2520.0 0.19 0.0681 0.3206 3087385 TimTec1_007540 C1CCC(C1)N2CCN(CC2)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G17 compound treatment 61560.0 -12700.0 -0.74 69120.0 -10500.0 -0.79 -1.0833 -0.9994 1235567 TimTec1_007541 CCOc1cccc(CN(C(=O)C)c2ccc3[nH]c(=O)[nH]c3c2)c1OCc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G18 compound treatment 37800.0 -36500.0 -2.12 55520.0 -24100.0 -1.82 -2.7846 -0.9973 3087386 TimTec1_007542 CC(C)(C)c1nc2C(C(=C(N)Oc2o1)C#N)c3ccc(Cl)cc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G19 compound treatment 48000.0 -26300.0 -1.52 60240.0 -19400.0 -1.47 -2.1141 -0.9998 3211569 TimTec1_007543 CC(Nc1nc(nc2ccccc12)N3CCOCC3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G20 compound treatment 46360.0 -27900.0 -1.62 66080.0 -13500.0 -1.02 -1.8687 -0.9755 3087387 TimTec1_007544 CC(NCc1sccc1C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G21 compound treatment 62960.0 -11300.0 -0.66 72320.0 -7280.0 -0.55 -0.8546 -0.9962 3211570 TimTec1_007545 CC(C)C(=O)Nc1ccc2oc(=O)ccc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G22 compound treatment 66520.0 -7790.0 -0.45 84080.0 4480.0 0.34 -0.0793 -0.1407 3087388 TimTec1_007546 Cn1nnc(n1)C(O)CNCc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G23 mock treatment 70720.0 -3590.0 -0.21 80520.0 916.0 0.07 -0.0978 -0.4468 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 G24 mock treatment 79640.0 5340.0 0.31 80840.0 1240.0 0.09 0.2847 0.8817 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H01 compound treatment 78440.0 4140.0 0.24 75400.0 -4200.0 -0.32 -0.0556 -0.1396 1275919 TimTec1_007547 COc1ccc(CC(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H02 compound treatment 12120.0 -62200.0 -3.6 16000.0 -63600.0 -4.81 -5.9519 -0.9898 3087389 TimTec1_007548 c1cncc(c1)c2nnc(nn2)c3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H03 compound treatment 66960.0 -7350.0 -0.43 82720.0 3120.0 0.24 -0.1341 -0.2756 1489991 TimTec1_007549 C(NC1CCN(Cc2ccccc2)CC1)C3CCCO3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H04 compound treatment 13880.0 -60400.0 -3.5 40920.0 -38700.0 -2.93 -4.546 -0.9961 3087390 TimTec1_007550 Cc1cc2ncn(CCOc3ccccc3)c2cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H05 compound treatment 60000.0 -14300.0 -0.83 73160.0 -6440.0 -0.49 -0.9309 -0.968 1235475 TimTec1_007551 Cc1ccc(OCC(=O)N2CCCCC2)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H06 compound treatment 56840.0 -17500.0 -1.01 61440.0 -18200.0 -1.37 -1.6877 -0.9886 3087391 TimTec1_007552 COc1ccc(Cn2c(C)ccc2C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H07 compound treatment 56640.0 -17700.0 -1.02 87680.0 8080.0 0.61 -0.2914 -0.2445 3211655 TimTec1_007553 O=C(CCC1CCCCC1)NCCCN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H08 compound treatment 59600.0 -14700.0 -0.85 76400.0 -3200.0 -0.24 -0.7739 -0.8737 1250277 TimTec1_007554 CSc1ccccc1C(=O)Nc2ccc(cc2)S(=O)(=O)N3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H09 compound treatment 65640.0 -8670.0 -0.5 84160.0 4560.0 0.34 -0.1111 -0.1824 3087392 TimTec1_007555 NC(=O)Cn1c(=O)n(CC(=O)N)c2ccccc2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H10 compound treatment 57440.0 -16900.0 -0.98 72920.0 -6680.0 -0.51 -1.0487 -0.9531 1733719 TimTec1_007556 CN(C(=O)CCN1C(=O)C(C)(C)Nc2ccccc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H11 compound treatment 42840.0 -31500.0 -1.82 57960.0 -21600.0 -1.64 -2.4475 -0.9986 3087393 TimTec1_007557 Nc1nc2ccc(cc2s1)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H12 compound treatment 17200.0 -57100.0 -3.31 30000.0 -49600.0 -3.75 -4.9945 -0.998 1201207 TimTec1_007558 Cc1ccc(cc1C)c2csc(n2)c3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H13 compound treatment 42120.0 -32200.0 -1.86 58520.0 -21100.0 -1.6 -2.447 -0.997 1304451 TimTec1_007559 CCC(=O)Nc1cccc(NC(=O)c2cc3ccccc3o2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H14 compound treatment 64640.0 -9670.0 -0.56 79280.0 -324.0 -0.02 -0.4133 -0.7373 3211656 TimTec1_007560 CCOc1ccc2[nH]c(=O)c(Cc3ccccc3)c(O)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H15 compound treatment 63840.0 -10500.0 -0.61 69280.0 -10300.0 -0.78 -0.9813 -0.9921 3211657 TimTec1_007561 CC(Sc1ccc(C)cc1)C(=O)NCc2ccncc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H16 compound treatment 6600.0 -67700.0 -3.92 7600.0 -72000.0 -5.45 -6.6277 -0.987 3087394 TimTec1_007562 Clc1cccc(c1)c2nc(no2)c3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H17 compound treatment 33320.0 -41000.0 -2.37 38720.0 -40900.0 -3.09 -3.8673 -0.9914 3211658 TimTec1_007563 CCC(=O)N1CCN(CC1)c2ccc(NCc3ccccc3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H18 compound treatment 62280.0 -12000.0 -0.7 77040.0 -2560.0 -0.19 -0.6299 -0.8709 1531690 TimTec1_007564 O=C1NCCCc2nc(Oc3ccccc3)sc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H19 compound treatment 32040.0 -42300.0 -2.45 39240.0 -40400.0 -3.06 -3.8919 -0.994 3211659 TimTec1_007565 O=C(NCCc1ccccc1)c2cnc3ccccn3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H20 compound treatment 61680.0 -12600.0 -0.73 72080.0 -7520.0 -0.57 -0.9199 -0.9923 3087395 TimTec1_007566 CC(=O)Nc1ccc(Oc2ccc(cc2)c3noc(C)n3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H21 compound treatment 28560.0 -45700.0 -2.65 40600.0 -39000.0 -2.95 -3.9617 -0.9986 3211660 TimTec1_007567 CC1=CC(C)(C)N(C(=O)CSc2ccccn2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H22 compound treatment 40920.0 -33400.0 -1.93 52240.0 -27400.0 -2.07 -2.8323 -0.9994 1143596 TimTec1_007568 Cc1cc(NCc2cccnc2)c3ccc(Cl)cc3n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H23 mock treatment 69680.0 -4630.0 -0.27 75520.0 -4080.0 -0.31 -0.4081 -0.9975 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 H24 mock treatment 74120.0 -185.0 -0.01 77600.0 -2000.0 -0.15 -0.1148 -0.7552 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I01 compound treatment 58160.0 -16100.0 -0.94 59960.0 -19600.0 -1.49 -1.7128 -0.975 3211661 TimTec1_007569 Cc1[nH]c2ccccc2c1C(=O)CSc3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I02 compound treatment 72600.0 -1710.0 -0.1 86520.0 6920.0 0.52 0.3003 0.5637 3087396 TimTec1_007570 CCCC(=O)Nc1nnc(s1)c2ccccc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I03 compound treatment 73760.0 -545.0 -0.03 79280.0 -324.0 -0.02 -0.0397 -0.9921 3211662 TimTec1_007571 Fc1ccc(NC(=O)C2CC(=O)N3CCN=C3S2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I04 compound treatment 63080.0 -11200.0 -0.65 86400.0 6800.0 0.51 -0.0961 -0.1159 1690088 TimTec1_007572 Cc1nc(=O)c(c(C)n1Cc2ccco2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I05 compound treatment 61800.0 -12500.0 -0.72 75160.0 -4440.0 -0.34 -0.7502 -0.9391 3087397 TimTec1_007573 Cc1cc2nc3CCCCc3c(n2n1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I06 compound treatment 53680.0 -20600.0 -1.19 73080.0 -6520.0 -0.49 -1.1941 -0.9236 3211663 TimTec1_007574 O=C(Nc1ncnc2sc3CCCc3c12)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I07 compound treatment 60640.0 -13700.0 -0.79 82080.0 2480.0 0.19 -0.4273 -0.5252 3087398 TimTec1_007575 COc1ccc(cc1)C2(CCOCC2)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I08 compound treatment 73600.0 -705.0 -0.04 80960.0 1360.0 0.1 0.0437 0.3956 1232670 TimTec1_007576 CC(=O)Nc1ccc(cc1)c2nc3ccc(NC(=O)C)cc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I09 compound treatment 63680.0 -10600.0 -0.62 74800.0 -4800.0 -0.36 -0.6924 -0.9685 3087399 TimTec1_007577 CC1(C)CC(=O)C2=C(C1)NC3=C(C2c4ccccc4C(F)(F)F)C(=O)CC(C)(C)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I10 compound treatment 58400.0 -15900.0 -0.92 74520.0 -5080.0 -0.38 -0.9237 -0.925 3211664 TimTec1_007578 CC(C)(C)c1oc(cc1CN2CCCC2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I11 compound treatment 65520.0 -8790.0 -0.51 76760.0 -2840.0 -0.22 -0.5121 -0.9267 3087400 TimTec1_007579 FC(F)(F)c1ccc(Cl)c(c1)c2ccc(C#N)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I12 compound treatment 57160.0 -17100.0 -0.99 65120.0 -14500.0 -1.1 -1.4776 -0.9988 3211665 TimTec1_007580 Cc1ccc(cc1)c2nc(C#N)c(NCc3ccc4OCOc4c3)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I13 compound treatment 51960.0 -22300.0 -1.29 64040.0 -15600.0 -1.18 -1.7485 -0.9989 1228965 TimTec1_007581 CCC(Oc1ccccc1)C(=O)Nc2nncs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I14 compound treatment 55600.0 -18700.0 -1.08 67560.0 -12000.0 -0.91 -1.4109 -0.9963 3211666 TimTec1_007582 Clc1c(sc2cc(Cl)ccc12)C(=O)NCC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I15 compound treatment 62840.0 -11500.0 -0.66 67640.0 -12000.0 -0.91 -1.11 -0.9884 1872119 TimTec1_007583 O=C(COC(=O)c1cnccn1)c2ccc(cc2)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I16 compound treatment 59240.0 -15100.0 -0.87 70040.0 -9560.0 -0.72 -1.1291 -0.9957 3087401 TimTec1_007584 COc1cccc(CN2C(=O)C3(C(=C(N)OC4=C3C(=O)CCC4)C#N)c5ccccc25)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I17 compound treatment 62080.0 -12200.0 -0.71 63640.0 -16000.0 -1.21 -1.3553 -0.9676 3211667 TimTec1_007585 CCc1cccc2c(C#N)cn(CC(=O)NCc3ccco3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I18 compound treatment 65720.0 -8590.0 -0.5 75200.0 -4400.0 -0.33 -0.5874 -0.9811 3211668 TimTec1_007586 Nc1c(Nc2ccc(F)cc2)sc3c(O)cc(=O)[nH]c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I19 compound treatment 55600.0 -18700.0 -1.08 65040.0 -14600.0 -1.1 -1.5458 -1.0 3087402 TimTec1_007587 COc1cc2[nH]c(=O)c(C(=O)NC(C)c3ccccc3)c(O)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I20 compound treatment 57280.0 -17000.0 -0.99 70480.0 -9120.0 -0.69 -1.1858 -0.9848 3211669 TimTec1_007588 CN(C(=O)Cn1cc(C#N)c2ccccc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I21 compound treatment 50240.0 -24100.0 -1.39 57520.0 -22100.0 -1.67 -2.1679 -0.9959 3211670 TimTec1_007589 O=C(Nc1ccc2oc(=O)ccc2c1)c3cc4ccccc4o3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I22 compound treatment 54360.0 -19900.0 -1.16 61320.0 -18300.0 -1.38 -1.7957 -0.996 3087403 TimTec1_007590 Cc1nnc2SC(=CC=Nn12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I23 mock treatment 80240.0 5940.0 0.34 90000.0 10400.0 0.79 0.7996 0.9311 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 I24 mock treatment 75280.0 975.0 0.06 75960.0 -3640.0 -0.28 -0.1551 -0.5508 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J01 compound treatment 33480.0 -40800.0 -2.37 33920.0 -45700.0 -3.46 -4.1177 -0.9828 3087404 TimTec1_007591 COc1ccc(OCCn2cc(C#N)c3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J02 compound treatment 42680.0 -31600.0 -1.83 49360.0 -30200.0 -2.29 -2.9144 -0.9939 3211671 TimTec1_007592 Cc1ccc(NC(=O)C2C3CC(C)(Oc4ccccc34)N(CCO)C2=O)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J03 compound treatment 44400.0 -29900.0 -1.73 60440.0 -19200.0 -1.45 -2.2509 -0.9961 3211672 TimTec1_007593 CC(=O)Nc1cccc(c1)c2csc(Nc3cccc(O)c3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J04 compound treatment 52040.0 -22300.0 -1.29 69880.0 -9720.0 -0.74 -1.4326 -0.9646 3087405 TimTec1_007594 CCOC(=O)c1cc(CN2CCOCC2)oc1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J05 compound treatment 21720.0 -52600.0 -3.05 34520.0 -45100.0 -3.41 -4.5674 -0.9984 1516475 TimTec1_007595 O=C(CC1CCCCC1)Nc2ccncc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J06 compound treatment 48560.0 -25700.0 -1.49 57880.0 -21700.0 -1.64 -2.2175 -0.9988 3087406 TimTec1_007596 O=C(Cn/1ccs\c1=N\C(=O)c2ccco2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J07 compound treatment 68000.0 -6310.0 -0.37 77800.0 -1800.0 -0.14 -0.3548 -0.9099 3211673 TimTec1_007597 CC1(C)CC(CC(C)(C)N1)NC(=O)c2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J08 compound treatment 50480.0 -23800.0 -1.38 64200.0 -15400.0 -1.17 -1.8005 -0.9965 1134872 TimTec1_007598 CC(C)n1c(NCc2ccccc2)nc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J09 compound treatment 70520.0 -3790.0 -0.22 76200.0 -3400.0 -0.26 -0.3372 -0.9968 3211674 TimTec1_007599 O=C(NCCN1CCCCC1)c2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J10 compound treatment 56840.0 -17500.0 -1.01 62680.0 -16900.0 -1.28 -1.6213 -0.9932 1510800 TimTec1_007600 Cc1cccc(NC(=O)c2cc(O)nc3ccccc23)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J11 compound treatment 55640.0 -18700.0 -1.08 60160.0 -19400.0 -1.47 -1.8054 -0.9885 3087407 TimTec1_007601 COc1ccc(OCC(=O)Nc2ncccn2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J12 compound treatment 57560.0 -16700.0 -0.97 61760.0 -17800.0 -1.35 -1.6411 -0.9868 3211675 TimTec1_007602 O=C(CSc1nc(nc2CCCCc12)c3ccccc3)N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J13 compound treatment 55440.0 -18900.0 -1.09 61360.0 -18200.0 -1.38 -1.7493 -0.9933 3087408 TimTec1_007603 NS(=O)(=O)c1csc(c1)C(=O)Nc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J14 compound treatment 55640.0 -18700.0 -1.08 68160.0 -11400.0 -0.87 -1.3772 -0.994 3211676 TimTec1_007604 Cc1ccc(cc1C)C(=O)CCc2nc3ccccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J15 compound treatment 55160.0 -19100.0 -1.11 74480.0 -5120.0 -0.39 -1.0586 -0.9009 1344730 TimTec1_007605 NC(=O)c1ccc(CN2CCc3ccccc3C2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J16 compound treatment 56960.0 -17300.0 -1.0 75520.0 -4080.0 -0.31 -0.9292 -0.8837 3211677 TimTec1_007606 CC(C)(Oc1ccc(Cl)cc1)C(=O)Nc2nnc[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J17 compound treatment 66520.0 -7790.0 -0.45 73160.0 -6440.0 -0.49 -0.6638 -0.9992 3211775 TimTec1_007607 O=C(NCCSC1CCCCC1)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J18 compound treatment 62360.0 -11900.0 -0.69 83560.0 3960.0 0.3 -0.2776 -0.3681 3087409 TimTec1_007608 OC(=O)CCCC(=O)Nc1ccc(cc1)c2nc3ccccc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J19 compound treatment 61520.0 -12800.0 -0.74 65920.0 -13700.0 -1.04 -1.2562 -0.9865 3211776 TimTec1_007609 Clc1ccc(CNC(=O)Cc2cccs2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J20 compound treatment 53760.0 -20500.0 -1.19 63400.0 -16200.0 -1.23 -1.709 -0.9999 3211777 TimTec1_007610 CCC(=O)Nc1cc(ccc1C)C(=O)OCC(=O)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J21 compound treatment 72840.0 -1470.0 -0.08 73400.0 -6200.0 -0.47 -0.3921 -0.8216 3087410 TimTec1_007611 CN1CCN(CC1)c2nc(=O)c3CCCCc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J22 compound treatment 55200.0 -19100.0 -1.11 64960.0 -14600.0 -1.11 -1.5665 -1.0 1397831 TimTec1_007612 C1Cc2nc3ccccc3c(N4CCOCC4)c2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J23 mock treatment 70480.0 -3830.0 -0.22 75160.0 -4440.0 -0.34 -0.3946 -0.9795 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 J24 mock treatment 69600.0 -4710.0 -0.27 68160.0 -11400.0 -0.87 -0.8053 -0.8868 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K01 compound treatment 59360.0 -14900.0 -0.87 65320.0 -14300.0 -1.08 -1.3768 -0.9939 3211778 TimTec1_007613 CC1(C)CC(=O)C2=C(C1)Nc3nn(c(O)c3C2c4ccco4)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K02 compound treatment 1760.0 -72500.0 -4.2 2200.0 -77400.0 -5.86 -7.115 -0.9867 1406475 TimTec1_007614 Nc1nc2ccccc2n1Cc3ccc(Cl)c(Cl)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K03 compound treatment 1880.0 -72400.0 -4.2 3120.0 -76500.0 -5.79 -7.0608 -0.9875 3087411 TimTec1_007615 Oc1ccccc1CNc2cnc3ccccc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K04 compound treatment 49440.0 -24900.0 -1.44 58160.0 -21400.0 -1.62 -2.1664 -0.9982 1715858 TimTec1_007616 COc1ccc(Nc2nnc(C)c3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K05 compound treatment 38760.0 -35500.0 -2.06 51400.0 -28200.0 -2.13 -2.9658 -0.9998 3087412 TimTec1_007617 CCOC(=O)c1cnc2cc(C)nn2c1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K06 compound treatment 29400.0 -44900.0 -2.6 49640.0 -30000.0 -2.27 -3.4435 -0.9977 3211779 TimTec1_007618 CC(OC(=O)CCc1c[nH]c2ccccc12)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K07 compound treatment 45920.0 -28400.0 -1.64 61240.0 -18400.0 -1.39 -2.1458 -0.9965 3211780 TimTec1_007619 Cc1cc(SCCOc2ccc(Cl)cc2Cl)nc(N)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K08 compound treatment 53560.0 -20700.0 -1.2 62200.0 -17400.0 -1.32 -1.7814 -0.999 1285395 TimTec1_007620 COc1cccc2cc(C(=O)N3CCN(CCO)CC3)c(=O)oc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K09 compound treatment 54600.0 -19700.0 -1.14 56920.0 -22700.0 -1.72 -2.0214 -0.9803 1875159 TimTec1_007621 CC(Oc1ccc(F)cc1)C(=O)NCc2ccncc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K10 compound treatment 33560.0 -40700.0 -2.36 46760.0 -32800.0 -2.49 -3.4272 -0.9997 3086523 TimTec1_007622 COC(=O)C(Cc1ccccc1)NC(=O)c2cc(oc2C)c3ccc4OCCOc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K11 compound treatment 38480.0 -35800.0 -2.08 47400.0 -32200.0 -2.44 -3.1914 -0.9968 3086524 TimTec1_007623 CCc1ccc(NC(=O)C2Cc3ccccc3C(=O)O2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K12 compound treatment 38240.0 -36100.0 -2.09 60840.0 -18800.0 -1.42 -2.4818 -0.9823 3086525 TimTec1_007624 Cc1nc(C#N)c(NCc2ccc(C)cc2)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K13 compound treatment 47440.0 -26900.0 -1.56 61160.0 -18400.0 -1.4 -2.0878 -0.9985 3086526 TimTec1_007625 O=C(Cc1cccc2ccccc12)NCCN3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K14 compound treatment 55560.0 -18700.0 -1.09 65960.0 -13600.0 -1.03 -1.4982 -0.9997 3086527 TimTec1_007626 O=C(NCCNC1CCCCC1)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K15 compound treatment 20280.0 -54000.0 -3.13 22840.0 -56800.0 -4.3 -5.2515 -0.9879 3211781 TimTec1_007627 Cc1cc(C(=O)OCC(=O)N(c2ccccc2)c3ccccc3)c4ccccc4n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K16 compound treatment 43160.0 -31100.0 -1.8 49640.0 -30000.0 -2.27 -2.8797 -0.9936 3086528 TimTec1_007628 CC(C)OC(=O)C1=C(N)Oc2cc(C)oc(=O)c2C1c3ccc(cc3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K17 compound treatment 42480.0 -31800.0 -1.84 56000.0 -23600.0 -1.79 -2.5672 -0.9999 3211782 TimTec1_007629 COc1ccc(cc1)C(=O)NCc2ccoc2C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K18 compound treatment 46840.0 -27500.0 -1.59 53120.0 -26500.0 -2.0 -2.5427 -0.9935 3086529 TimTec1_007630 CC(C)N1C(=O)C(O)(CC(=O)c2ccccc2O)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K19 compound treatment 47040.0 -27300.0 -1.58 48960.0 -30600.0 -2.32 -2.7572 -0.9825 1862563 TimTec1_007631 O=C(COc1cccc2ccccc12)Nc3ccc(CN4CCOCC4)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K20 compound treatment 55960.0 -18300.0 -1.06 51720.0 -27900.0 -2.11 -2.244 -0.9496 3211783 TimTec1_007632 CCOc1cc(CNn2cnnc2)cc(Cl)c1OCC(=O)NC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K21 compound treatment 34560.0 -39700.0 -2.3 42280.0 -37300.0 -2.83 -3.626 -0.9948 3086530 TimTec1_007633 NCc1ccc(cc1)c2nc3ccccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K22 compound treatment 47520.0 -26800.0 -1.55 47120.0 -32500.0 -2.46 -2.836 -0.9754 3086531 TimTec1_007634 Cc1nn2c3cc(ccc3nc2c4ccccc14)N5CCOCC5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K23 mock treatment 54680.0 -19600.0 -1.14 62960.0 -16600.0 -1.26 -1.6948 -0.9987 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 K24 mock treatment 61440.0 -12900.0 -0.75 65000.0 -14600.0 -1.11 -1.3087 -0.9816 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L01 compound treatment 49640.0 -24700.0 -1.43 62080.0 -17500.0 -1.33 -1.9484 -0.9993 3211784 TimTec1_007635 Fc1ccc(Cn2cc(C#N)c3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L02 compound treatment 61480.0 -12800.0 -0.74 64560.0 -15000.0 -1.14 -1.3306 -0.9786 3211785 TimTec1_007636 CC1(C)CNC(=O)c2sc(NC(=O)c3ccccc3Cl)nc2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L03 compound treatment 78000.0 3700.0 0.21 80920.0 1320.0 0.1 0.2218 0.9394 3086532 TimTec1_007637 Cc1ccc2[nH]c(CCC(=O)O)nc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L04 compound treatment 54600.0 -19700.0 -1.14 61320.0 -18300.0 -1.38 -1.7859 -0.9954 1861878 TimTec1_007638 O=C(Nc1ccccc1N2CCCC2)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L05 compound treatment 59520.0 -14800.0 -0.86 68680.0 -10900.0 -0.83 -1.1904 -0.9998 1581232 TimTec1_007639 CCc1ccc(OCC(=O)N2CCOCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L06 compound treatment 54560.0 -19700.0 -1.14 58960.0 -20600.0 -1.56 -1.9139 -0.9882 3211786 TimTec1_007640 O=C1CCCC2=C1C(C3=C(CCCC3=O)N2)c4cccc5ccccc45 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L07 compound treatment 54920.0 -19400.0 -1.12 73320.0 -6280.0 -0.48 -1.1305 -0.9269 3086533 TimTec1_007641 O=C(NCCN1CCOCC1)c2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L08 compound treatment 11880.0 -62400.0 -3.62 11360.0 -68200.0 -5.17 -6.2101 -0.9848 1650547 TimTec1_007642 Oc1ccc(COCc2ccccc2)c3cccnc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L09 compound treatment 64120.0 -10200.0 -0.59 77040.0 -2560.0 -0.19 -0.5545 -0.8926 3086534 TimTec1_007643 CC(CN1CCCC1)OC(=O)c2ccccc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L10 compound treatment 54920.0 -19400.0 -1.12 75880.0 -3720.0 -0.28 -0.9935 -0.858 1613918 TimTec1_007644 OC(=O)c1c(NC(=O)c2cccs2)scc1c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L11 compound treatment 59880.0 -14400.0 -0.84 73240.0 -6360.0 -0.48 -0.9316 -0.9657 3211787 TimTec1_007645 O=C(NCCN1CCOCC1)c2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L12 compound treatment 63600.0 -10700.0 -0.62 63800.0 -15800.0 -1.2 -1.2844 -0.9532 3086535 TimTec1_007646 CN(CC(=O)NC1CCCCC1)S(=O)(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L13 compound treatment 56240.0 -18100.0 -1.05 60080.0 -19500.0 -1.48 -1.7851 -0.9857 1502643 TimTec1_007647 CCOc1ccc(NCC(=O)Nc2ccc(F)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L14 compound treatment 45560.0 -28700.0 -1.67 40200.0 -39400.0 -2.98 -3.2867 -0.9621 3211788 TimTec1_007648 CCOc1ccc(cc1)C(=O)CCc2nc3ccccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L15 compound treatment 69080.0 -5230.0 -0.3 70560.0 -9040.0 -0.68 -0.6981 -0.9327 3086536 TimTec1_007649 Cc1ccc(cc1n2cccc2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L16 compound treatment 56160.0 -18100.0 -1.05 60800.0 -18800.0 -1.42 -1.7498 -0.9889 1742683 TimTec1_007650 CC(Oc1cccc(Cl)c1)C(=O)N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L17 compound treatment 57160.0 -17100.0 -0.99 57920.0 -21700.0 -1.64 -1.863 -0.9711 3211789 TimTec1_007651 O=C(NCCSc1ccccc1)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L18 compound treatment 61840.0 -12500.0 -0.72 69840.0 -9760.0 -0.74 -1.0333 -0.9999 3211790 TimTec1_007652 O=C(Cc1cccs1)Nc2cccc(c2)C(=O)Nc3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L19 compound treatment 54960.0 -19300.0 -1.12 60080.0 -19500.0 -1.48 -1.8375 -0.9907 1196911 TimTec1_007653 Cc1onc(c1C(=O)NC2CCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L20 compound treatment 66160.0 -8150.0 -0.47 69200.0 -10400.0 -0.79 -0.8905 -0.97 1436556 TimTec1_007654 Cc1ccc(cc1C)C(=O)COC(=O)c2cnccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L21 compound treatment 63400.0 -10900.0 -0.63 68920.0 -10700.0 -0.81 -1.0186 -0.9925 3086537 TimTec1_007655 CC1=C(Sc2ccccc2N1)C(=O)Nc3ccccc3C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L22 compound treatment 26600.0 -47700.0 -2.76 32280.0 -47300.0 -3.58 -4.4873 -0.9918 3211791 TimTec1_007656 CC(C)C(=O)Nc1nc(cs1)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L23 mock treatment 70720.0 -3590.0 -0.21 69000.0 -10600.0 -0.8 -0.7144 -0.8617 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 L24 mock treatment 69800.0 -4510.0 -0.26 75360.0 -4240.0 -0.32 -0.4117 -0.9947 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M01 compound treatment 52160.0 -22100.0 -1.28 65120.0 -14500.0 -1.1 -1.6825 -0.9969 3211792 TimTec1_007657 COc1ccccc1NC(=O)C2=C(C)Nc3ccccc3S2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M02 compound treatment 15200.0 -59100.0 -3.42 16680.0 -62900.0 -4.76 -5.7894 -0.9869 3086538 TimTec1_007658 COCc1nc2ccccc2n1Cc3cccc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M03 compound treatment 68240.0 -6070.0 -0.35 69800.0 -9800.0 -0.74 -0.7732 -0.9417 3211793 TimTec1_007659 CCOC(=O)C1C2OC3(CN(C4CCCC4)C(=O)C13)C=C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M04 compound treatment 49840.0 -24500.0 -1.42 65960.0 -13600.0 -1.03 -1.7326 -0.9879 1193736 TimTec1_007660 CNC(=O)c1ccc(Nc2nnc(C)c3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M05 compound treatment 57240.0 -17100.0 -0.99 69920.0 -9680.0 -0.73 -1.2174 -0.9892 1412527 TimTec1_007661 Cc1cc(C)cc(NC(=O)COc2ccc(cc2)N3CC(CC3=O)C(=O)NCC=C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M06 compound treatment 38800.0 -35500.0 -2.06 44400.0 -35200.0 -2.66 -3.3388 -0.9918 3211794 TimTec1_007662 CCOc1ccccc1C(=O)N(Cc2cc3ccccc3nc2O)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M07 compound treatment 49280.0 -25000.0 -1.45 60040.0 -19600.0 -1.48 -2.0724 -0.9999 3086539 TimTec1_007663 O=C(Nc1cccc2ccccc12)C3CC(=O)OC43CCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M08 compound treatment 62160.0 -12100.0 -0.7 73520.0 -6080.0 -0.46 -0.8232 -0.9789 3086540 TimTec1_007664 Clc1snc(C(=O)CC#N)c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M09 compound treatment 29160.0 -45100.0 -2.62 44480.0 -35100.0 -2.66 -3.7295 -1.0 3211795 TimTec1_007665 O=C(C1CC1)c2cn(CCOc3ccccc3)c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M10 compound treatment 58040.0 -16300.0 -0.94 65080.0 -14500.0 -1.1 -1.4437 -0.9971 1574331 TimTec1_007666 COC(=O)CC1=C(C(=O)OC)C2(C(=O)Nc3ccccc32)C(=C(N)O1)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M11 compound treatment 31560.0 -42700.0 -2.48 42880.0 -36700.0 -2.78 -3.7168 -0.9983 3086541 TimTec1_007667 O=c1oc2ccccc2n1CCOc3cccc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M12 compound treatment 37640.0 -36700.0 -2.12 46000.0 -33600.0 -2.54 -3.3007 -0.996 1870621 TimTec1_007668 COC(=O)C1=C(C)NC(=O)NC1/C=C/c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M13 compound treatment 40400.0 -33900.0 -1.96 49600.0 -30000.0 -2.27 -2.9949 -0.9974 3086542 TimTec1_007669 O=C(Cc1cccc2ccccc12)Nc3ccc(CCC(=O)N4CCCC4)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M14 compound treatment 4920.0 -69400.0 -4.02 6520.0 -73100.0 -5.53 -6.7543 -0.9877 3211878 TimTec1_007670 FC(F)(F)c1ccc(Cn2cnc3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M15 compound treatment 45840.0 -28500.0 -1.65 60520.0 -19100.0 -1.44 -2.1876 -0.9978 1522627 TimTec1_007671 CC(C)(C)C1CCc2c(C(=O)N)c(N)sc2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M16 compound treatment 58480.0 -15800.0 -0.92 66040.0 -13600.0 -1.03 -1.3743 -0.9984 3086543 TimTec1_007672 Cc1cc(CO)c(C)n1c2ccncc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M17 compound treatment 30200.0 -44100.0 -2.56 38120.0 -41500.0 -3.14 -4.0273 -0.9948 3211879 TimTec1_007673 COC(=O)c1cn(Cc2ccc(C#N)cc2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M18 compound treatment 60600.0 -13700.0 -0.79 69640.0 -9960.0 -0.75 -1.0948 -0.9997 1572395 TimTec1_007674 NC(=O)C1CCN(CC1)C(=O)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M19 compound treatment 57400.0 -16900.0 -0.98 67880.0 -11700.0 -0.89 -1.3201 -0.9988 3211880 TimTec1_007675 CN1CCN(CC1)c2ccc(NC(=O)COc3cccc4ccccc34)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M20 compound treatment 59560.0 -14700.0 -0.85 55280.0 -24300.0 -1.84 -1.906 -0.939 3086544 TimTec1_007676 O=C(COc1cccc(NC(=O)c2ccco2)c1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M21 compound treatment 48320.0 -26000.0 -1.51 51480.0 -28100.0 -2.13 -2.5699 -0.9856 3211881 TimTec1_007677 COC(=O)Cn1cc(C(=O)c2ccccc2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M22 compound treatment 54760.0 -19500.0 -1.13 57680.0 -21900.0 -1.66 -1.9742 -0.9826 1168606 TimTec1_007678 Oc1ccc(cc1)c2nc(cs2)c3c[nH]c4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M23 mock treatment 65840.0 -8470.0 -0.49 83320.0 3720.0 0.28 -0.1479 -0.2616 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 M24 mock treatment 72520.0 -1790.0 -0.1 78240.0 -1360.0 -0.1 -0.1461 -1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N01 compound treatment 51680.0 -22600.0 -1.31 66040.0 -13600.0 -1.03 -1.6529 -0.9927 3211882 TimTec1_007679 O=C(Cn1cc(C#N)c2ccccc12)N3CCc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N02 compound treatment 75120.0 815.0 0.05 74480.0 -5120.0 -0.39 -0.2409 -0.6165 3086545 TimTec1_007680 Fc1ccc(cc1F)C(=O)NCC2CCCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N03 compound treatment 52400.0 -21900.0 -1.27 63480.0 -16100.0 -1.22 -1.7604 -0.9998 3211883 TimTec1_007681 CC1(C)CC(=O)c2sc(NC(=O)CCCc3ccccc3)nc2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N04 compound treatment 53840.0 -20500.0 -1.19 58600.0 -21000.0 -1.59 -1.9626 -0.9896 3086546 TimTec1_007682 CC(=O)Nc1ccc(cc1)n2cccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N05 compound treatment 46600.0 -27700.0 -1.61 61440.0 -18200.0 -1.37 -2.1072 -0.997 1245976 TimTec1_007683 CC(C)c1ccc(OCC(=O)N2CCC(CC2)C(=O)N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N06 compound treatment 51040.0 -23300.0 -1.35 55560.0 -24000.0 -1.82 -2.24 -0.9891 3211884 TimTec1_007684 CCCOc1ccc(NC(=O)C2CN(C(C)C)C(=O)C2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N07 compound treatment 54680.0 -19600.0 -1.14 68280.0 -11300.0 -0.86 -1.4101 -0.9903 3086547 TimTec1_007685 Cc1cc(C)cc(c1)C(=O)Nc2nnc[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N08 compound treatment 46000.0 -28300.0 -1.64 62960.0 -16600.0 -1.26 -2.0504 -0.9915 3211885 TimTec1_007686 COc1ccccc1OCC(=O)Nc2sc3CCCCc3c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N09 compound treatment 58560.0 -15700.0 -0.91 68960.0 -10600.0 -0.81 -1.2147 -0.9981 3086548 TimTec1_007687 CC(CN1CCCC1)OC(=O)c2ccccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N10 compound treatment 46800.0 -27500.0 -1.59 53280.0 -26300.0 -1.99 -2.5358 -0.9939 1285500 TimTec1_007688 OCCNC(=O)c1cc2sc3ccccc3c2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N11 compound treatment 17200.0 -57100.0 -3.31 20600.0 -59000.0 -4.47 -5.4976 -0.9891 3086549 TimTec1_007689 Cc1ccc(cc1C)C2OC3C=CC(=CC3=N2)NC(=O)c4cccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N12 compound treatment 28280.0 -46000.0 -2.67 30880.0 -48700.0 -3.69 -4.4934 -0.9873 3211886 TimTec1_007690 Cc1ccc(C)n1c2oc(C)c(C)c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N13 compound treatment 51080.0 -23200.0 -1.35 61400.0 -18200.0 -1.38 -1.9258 -0.9999 3211887 TimTec1_007691 Cc1cc(O)n2nc(NC(=O)c3cccs3)nc2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N14 compound treatment 57760.0 -16500.0 -0.96 67920.0 -11700.0 -0.88 -1.3032 -0.9992 3086550 TimTec1_007692 Clc1ccccc1OCC(=O)N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N15 compound treatment 33800.0 -40500.0 -2.35 40560.0 -39000.0 -2.96 -3.7492 -0.9935 3211888 TimTec1_007693 Cc1cccc(NC(=O)Cn2cc(C(=O)C3CC3)c4ccccc24)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N16 compound treatment 55440.0 -18900.0 -1.09 61240.0 -18400.0 -1.39 -1.7558 -0.9929 3086551 TimTec1_007694 OCc1cn(nc1c2cccnc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N17 compound treatment 5080.0 -69200.0 -4.01 7160.0 -72400.0 -5.48 -6.7135 -0.9882 1673666 TimTec1_007695 COc1ccc(CNC(Cc2ccccc2)c3ccccc3)c(OC)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N18 compound treatment 52720.0 -21600.0 -1.25 68040.0 -11600.0 -0.88 -1.5032 -0.9848 3086552 TimTec1_007696 Clc1ccc(CSCC(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N19 compound treatment 57160.0 -17100.0 -0.99 62880.0 -16700.0 -1.27 -1.5975 -0.9928 3211889 TimTec1_007697 Cc1onc(c1C(=O)Nc2cccnc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N20 compound treatment 51520.0 -22800.0 -1.32 57320.0 -22300.0 -1.69 -2.1262 -0.9926 3211890 TimTec1_007698 CC(=O)Nc1ccc(Oc2cc(C#N)c(C#N)cc2N3CCOCC3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N21 compound treatment 64040.0 -10300.0 -0.59 61680.0 -17900.0 -1.36 -1.3799 -0.9315 3086553 TimTec1_007699 O=C(NC1=NC(=O)CC2N1CCNC2=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N22 compound treatment 55000.0 -19300.0 -1.12 64280.0 -15300.0 -1.16 -1.6111 -0.9998 1456550 TimTec1_007700 O=C(Cn1cnc2ccccc2c1=O)OC3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N23 mock treatment 67000.0 -7310.0 -0.42 66080.0 -13500.0 -1.02 -1.0231 -0.9236 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 N24 mock treatment 65680.0 -8630.0 -0.5 76080.0 -3520.0 -0.27 -0.542 -0.9568 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O01 compound treatment 86240.0 11900.0 0.69 79920.0 316.0 0.02 0.5059 0.7311 3211891 TimTec1_007701 CCOc1ccc(NC2=NC(CC(=O)N2)C(=O)NCc3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O02 compound treatment 27400.0 -46900.0 -2.72 45120.0 -34500.0 -2.61 -3.7673 -0.9998 1687553 TimTec1_007702 Cc1ccc(cc1)C(=O)Cn2c3ncnn3c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O03 compound treatment 67280.0 -7030.0 -0.41 66480.0 -13100.0 -0.99 -0.9902 -0.9224 3211892 TimTec1_007703 CCOC(=O)Cc1[nH]nc2OC(=C(C#N)C(c12)c3ccc(Cl)cc3)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O04 compound treatment 55760.0 -18500.0 -1.07 60440.0 -19200.0 -1.45 -1.7855 -0.9891 3086792 TimTec1_007704 COc1cccc(CNc2nc3ccccc3n2CCN4CCOCC4)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O05 compound treatment 58440.0 -15900.0 -0.92 66640.0 -13000.0 -0.98 -1.3438 -0.9995 3086793 TimTec1_007705 COc1ccc(cc1)c2ccc(CCC(=O)O)n2C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O06 compound treatment 52120.0 -22200.0 -1.29 69520.0 -10100.0 -0.76 -1.4486 -0.969 3086794 TimTec1_007706 COc1ccc2nc(O)c(CN(C(=O)C)c3cccc(C)c3)cc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O07 compound treatment 61000.0 -13300.0 -0.77 60920.0 -18700.0 -1.41 -1.5451 -0.9593 3086795 TimTec1_007707 COc1ccc(Cl)cc1n2cnc3sc(C)c(C)c3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O08 compound treatment 69560.0 -4750.0 -0.27 74240.0 -5360.0 -0.41 -0.4815 -0.982 3086796 TimTec1_007708 CN(C)C(=O)c1ccccc1NC(=O)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O09 compound treatment 54760.0 -19500.0 -1.13 65280.0 -14300.0 -1.08 -1.5674 -0.9998 3086797 TimTec1_007709 CC(C)(C)OC(=O)CN1C(=O)c2ccccc2S1(=O)=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O10 compound treatment 34120.0 -40200.0 -2.33 41800.0 -37800.0 -2.86 -3.6697 -0.9948 3086798 TimTec1_007710 Cc1ccc(N2CCN(CC2)C(=O)c3cccs3)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O11 compound treatment 40080.0 -34200.0 -1.98 48240.0 -31400.0 -2.37 -3.0808 -0.996 3211893 TimTec1_007711 O=c1oc2ccccc2n1CCCOc3ccc4ccccc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O12 compound treatment 71720.0 -2590.0 -0.15 80960.0 1360.0 0.1 -0.0333 -0.1835 1875235 TimTec1_007712 CCn1c(=N)c(C#N)cc2c(=O)n3ccccc3nc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O13 compound treatment 49640.0 -24700.0 -1.43 53720.0 -25900.0 -1.96 -2.3959 -0.988 1241828 TimTec1_007713 CCC(=O)Nc1sc2CCCc2c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O14 compound treatment 60520.0 -13800.0 -0.8 67400.0 -12200.0 -0.92 -1.2179 -0.9974 3211894 TimTec1_007714 FC(F)(F)c1ccccc1CNCCc2c[nH]c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O15 compound treatment 69240.0 -5070.0 -0.29 72560.0 -7040.0 -0.53 -0.5845 -0.9604 3211895 TimTec1_007715 CCn1nnc(NC(=O)Cc2ccccc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O16 compound treatment 55040.0 -19300.0 -1.12 62600.0 -17000.0 -1.29 -1.6994 -0.9975 3086799 TimTec1_007716 CC(=O)N1CCN(CC1)c2ccc(NC(=O)COc3ccc4ccccc4c3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O17 compound treatment 63200.0 -11100.0 -0.64 67160.0 -12400.0 -0.94 -1.121 -0.9827 3211896 TimTec1_007717 Cc1ccc2nc(O)cc(C(=O)OCC(=O)c3ccc(F)cc3)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O18 compound treatment 68960.0 -5350.0 -0.31 79680.0 76.3 0.01 -0.2149 -0.6938 3211897 TimTec1_007718 Nc1nonc1c2nc3ccccc3n2CC(=O)Nc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O19 compound treatment 69240.0 -5070.0 -0.29 78040.0 -1560.0 -0.12 -0.2912 -0.9203 3086800 TimTec1_007719 CC(=O)Nc1c(C)nc2ncnn2c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O20 compound treatment 46400.0 -27900.0 -1.62 52640.0 -27000.0 -2.04 -2.5864 -0.9933 3211898 TimTec1_007720 Cc1ccc2nc(C)cc(C(=O)OCC(=O)C(C)(C)C)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O21 compound treatment 42440.0 -31900.0 -1.85 47360.0 -32200.0 -2.44 -3.0313 -0.9905 1528103 TimTec1_007721 Clc1ccc(Cl)c(NC(=O)C2COc3ccccc3O2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O22 compound treatment 40640.0 -33700.0 -1.95 43520.0 -36100.0 -2.73 -3.3105 -0.9864 3211899 TimTec1_007722 N(c1nc(cs1)c2cccs2)c3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O23 mock treatment 68000.0 -6310.0 -0.37 82840.0 3240.0 0.24 -0.0851 -0.1935 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 O24 mock treatment 82360.0 8060.0 0.47 79760.0 156.0 0.01 0.3384 0.7248 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P01 compound treatment 67520.0 -6790.0 -0.39 75840.0 -3760.0 -0.28 -0.4794 -0.9875 1787717 TimTec1_007723 CCN(CC)C(=O)Cn1cc(C#N)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P02 compound treatment 53160.0 -21100.0 -1.23 60200.0 -19400.0 -1.47 -1.9048 -0.9959 1448248 TimTec1_007724 CC(Oc1ccccc1)C(=O)NCc2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P03 compound treatment 47040.0 -27300.0 -1.58 62680.0 -16900.0 -1.28 -2.0228 -0.9946 1288426 TimTec1_007725 CC(=O)Nc1ccccc1NC(=O)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P04 compound treatment 63840.0 -10500.0 -0.61 70440.0 -9160.0 -0.69 -0.9192 -0.9978 3211900 TimTec1_007726 COc1ccc(NC(=O)COC(=O)C2CN(Cc3ccc(C)cc3)C(=O)C2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P05 compound treatment 21080.0 -53200.0 -3.08 31960.0 -47600.0 -3.61 -4.7306 -0.997 3211901 TimTec1_007727 Clc1ccc(OCCCC(=O)NCc2ccncc2)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P06 compound treatment 51160.0 -23100.0 -1.34 67280.0 -12300.0 -0.93 -1.6078 -0.9843 3086801 TimTec1_007728 CC(=O)Nc1ccc(NC(=O)C2CN(Cc3ccccc3)C(=O)C2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P07 compound treatment 52680.0 -21600.0 -1.25 68520.0 -11100.0 -0.84 -1.4792 -0.981 3211960 TimTec1_007729 Cc1ccc(OCC(=O)n2cnnc2N)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P08 compound treatment 44520.0 -29800.0 -1.73 48920.0 -30700.0 -2.32 -2.8626 -0.9893 1516476 TimTec1_007730 CC(C)(C)Nc1ncnc2n(Cc3ccccc3)ncc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P09 compound treatment 59080.0 -15200.0 -0.88 61280.0 -18300.0 -1.39 -1.6045 -0.9761 3086802 TimTec1_007731 COc1ccccc1C(=O)OC2CCN(C)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P10 compound treatment 42280.0 -32000.0 -1.86 57600.0 -22000.0 -1.67 -2.4897 -0.9985 3086803 TimTec1_007732 Cc1sc2nc(oc(=O)c2c1C)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P11 compound treatment 46760.0 -27500.0 -1.6 56120.0 -23500.0 -1.78 -2.3854 -0.9986 1413821 TimTec1_007733 CCCC(=O)Nc1cccc(NC(=O)c2cccnc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P12 compound treatment 51600.0 -22700.0 -1.32 62640.0 -17000.0 -1.28 -1.8381 -0.9999 3086804 TimTec1_007734 FC(F)(F)c1nn(CC(=O)N2CCCC2)c3CCCc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P13 compound treatment 48120.0 -26200.0 -1.52 63440.0 -16200.0 -1.22 -1.9379 -0.9943 1351196 TimTec1_007735 COc1ccccc1NC(=O)CC2N(C(=O)c3ccccc3)c4ccccc4NC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P14 compound treatment 14280.0 -60000.0 -3.48 21200.0 -58400.0 -4.42 -5.5851 -0.9929 3086805 TimTec1_007736 Cc1cccc(Nc2nc(cs2)c3ccc(F)cc3)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P15 compound treatment 34480.0 -39800.0 -2.31 43720.0 -35900.0 -2.72 -3.5522 -0.9967 3211961 TimTec1_007737 O=C(C1CC1)c2cn(Cc3ccccc3)c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P16 compound treatment 51080.0 -23200.0 -1.35 63440.0 -16200.0 -1.22 -1.8166 -0.9989 3086806 TimTec1_007738 Cc1ccc(cc1)c2nn(CCC#N)cc2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P17 compound treatment 45320.0 -29000.0 -1.68 63400.0 -16200.0 -1.23 -2.0548 -0.9881 3211962 TimTec1_007739 COc1cc(OC)c(cc1OC)C(=O)NCC2CCCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P18 compound treatment 53680.0 -20600.0 -1.19 67320.0 -12300.0 -0.93 -1.5024 -0.9923 1878712 TimTec1_007740 CC1=C(C)CC(C(C1)C(=O)O)C(=O)N2CCN(Cc3ccccc3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P19 compound treatment 39120.0 -35200.0 -2.04 50120.0 -29500.0 -2.23 -3.0196 -0.999 1288850 TimTec1_007741 O=C(Nc1ccc2OCOc2c1)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P20 compound treatment 47320.0 -27000.0 -1.56 62800.0 -16800.0 -1.27 -2.0049 -0.9948 3211963 TimTec1_007742 Clc1ccc(NC(=O)NCC2CCCO2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P21 compound treatment 54800.0 -19500.0 -1.13 57400.0 -22200.0 -1.68 -1.9875 -0.9813 3086807 TimTec1_007743 CCCc1nc(Nc2nc3ccccc3o2)ncc1C(=O)OCC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P22 compound treatment 58520.0 -15800.0 -0.91 67160.0 -12400.0 -0.94 -1.3127 -0.9999 1454174 TimTec1_007744 O=C(Cn1cnc2ccccc2c1=O)OCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P23 mock treatment 66000.0 -8310.0 -0.48 72720.0 -6880.0 -0.52 -0.7087 -0.9992 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2084 P24 mock treatment 69440.0 -4870.0 -0.28 66400.0 -13200.0 -1.0 -0.906 -0.8725 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A01 compound treatment 72160.0 20000.0 1.16 57800.0 -7030.0 -0.53 0.4421 0.3471 3086808 TimTec1_007745 CCC(=O)c1cc(c2nc3ccccc3n2C)n(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A02 compound treatment 82200.0 30000.0 1.74 66240.0 1410.0 0.11 1.3052 0.7491 3211964 TimTec1_007746 COC(=O)C1=C(C)OC(=C(C#N)C21C(=O)N(C)c3ccccc32)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A03 compound treatment 75000.0 22800.0 1.32 59480.0 -5350.0 -0.4 0.6484 0.469 3211965 TimTec1_007747 OC(=O)C1C2OC3(CN(C(=O)C13)c4ccc(Cl)c(F)c4)C=C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A04 compound treatment 87760.0 35600.0 2.06 64640.0 -190.0 -0.01 1.4473 0.7022 3086809 TimTec1_007748 CN1CCN(CC1)c2nc(NCC3CCCO3)c4ccccc4n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A05 compound treatment 44720.0 -7460.0 -0.43 38600.0 -26200.0 -1.99 -1.7097 -0.8414 3211966 TimTec1_007749 Cc1ccccc1c2nc3cc(NC(=O)C4CC4)ccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A06 compound treatment 79880.0 27700.0 1.6 57920.0 -6910.0 -0.52 0.7648 0.4532 3086810 TimTec1_007750 Oc1nc2ccccc2cc1c3noc(n3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A07 compound treatment 43640.0 -8540.0 -0.5 38920.0 -25900.0 -1.96 -1.7368 -0.8586 1670347 TimTec1_007751 CCOC(=O)c1cnc2c(Cl)cccc2c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A08 compound treatment 77200.0 25000.0 1.45 69400.0 4570.0 0.35 1.2695 0.8519 3211967 TimTec1_007752 Clc1ccccc1c2ccc(o2)C(=O)NCc3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A09 compound treatment 39720.0 -12500.0 -0.72 8040.0 -56800.0 -4.3 -3.5502 -0.8145 1861788 TimTec1_007753 O=C(COc1ccccc1)Nc2ccccc2N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A10 compound treatment 77120.0 24900.0 1.44 59920.0 -4910.0 -0.37 0.7588 0.5086 1428766 TimTec1_007754 COc1ccc2oc(=O)c(cc2c1)C(=O)N(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A11 compound treatment 75800.0 23600.0 1.37 65840.0 1010.0 0.08 1.0216 0.7455 3086811 TimTec1_007755 CCN(CC)C(=O)Cn1cc(C(=O)CC)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A12 compound treatment 87640.0 35500.0 2.05 63000.0 -1830.0 -0.14 1.3546 0.6579 3211968 TimTec1_007756 Cc1cc(C)n(n1)c2nc3ccccc3[nH]c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A13 compound treatment 82040.0 29900.0 1.73 66720.0 1890.0 0.14 1.3243 0.763 3086812 TimTec1_007757 CCCC(=O)Nc1ccc2C(=O)OCc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A14 compound treatment 79720.0 27500.0 1.6 63440.0 -1390.0 -0.11 1.0537 0.659 1600399 TimTec1_007758 CC1CN(C)CC(C)C1(O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A15 compound treatment 65040.0 12900.0 0.74 58880.0 -5950.0 -0.45 0.2082 0.2392 1787715 TimTec1_007759 O=C(Cn1cc(C#N)c2ccccc12)N3CCc4ccccc4C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A16 compound treatment 40840.0 -11300.0 -0.66 25040.0 -39800.0 -3.01 -2.5945 -0.8416 3086813 TimTec1_007760 COc1ccccc1NC(CC(=O)c2ccccc2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A17 compound treatment 53560.0 1380.0 0.08 46120.0 -18700.0 -1.42 -0.9451 -0.6662 3211969 TimTec1_007761 CCc1cc2c(ncnc2s1)N3CCN(CC3)c4nc(C)cc(C)n4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A18 compound treatment 71520.0 19300.0 1.12 58040.0 -6790.0 -0.51 0.4287 0.3478 1862419 TimTec1_007762 O=C(Cc1ccccc1)Nc2ccccc2N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A19 compound treatment 77840.0 25700.0 1.49 67240.0 2410.0 0.18 1.1801 0.788 1358875 TimTec1_007763 CC1(C)C2(C)CCC1(CC2=O)C(=O)NC3CC(C)(C)NC(C)(C)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A20 compound treatment 72080.0 19900.0 1.15 46080.0 -18800.0 -1.42 -0.1885 -0.1031 1449265 TimTec1_007764 Cc1ccc(NC(=O)COC(=O)c2cccs2)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A21 compound treatment 74720.0 22500.0 1.31 64240.0 -590.0 -0.04 0.8917 0.6825 3211970 TimTec1_007765 Cc1cc(NC(=O)Cc2cccc3ccccc23)no1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A22 compound treatment 55600.0 3420.0 0.2 58160.0 -6670.0 -0.5 -0.217 -0.4002 1377950 TimTec1_007766 Cc1cc(N)cc2nc([nH]c12)c3ccc(N)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A23 mock treatment 56560.0 4380.0 0.25 50480.0 -14400.0 -1.09 -0.5888 -0.5279 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 A24 mock treatment 71040.0 18900.0 1.09 67080.0 2250.0 0.17 0.8929 0.8076 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B01 compound treatment 78720.0 26500.0 1.54 66600.0 1770.0 0.13 1.1819 0.7658 1095008 TimTec1_007767 Cn1c(nc2c(=O)n(C)c(=O)[nH]c12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B02 compound treatment 60560.0 8380.0 0.49 56720.0 -8110.0 -0.61 -0.0909 -0.1162 3211971 TimTec1_007768 CC(C)(C)C(=O)COC(=O)c1cccc(NC(=O)c2ccco2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B03 compound treatment 75320.0 23100.0 1.34 64160.0 -670.0 -0.05 0.912 0.6799 3086814 TimTec1_007769 O=C(Cc1cccs1)Nc2nnc(Cc3ccccc3)s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B04 compound treatment 85600.0 33400.0 1.94 68200.0 3370.0 0.26 1.5494 0.7934 3211972 TimTec1_007770 Cc1cc(nn1CC(=O)NCc2cccs2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B05 compound treatment 75640.0 23500.0 1.36 59040.0 -5790.0 -0.44 0.6511 0.4559 1280407 TimTec1_007771 Cc1ccccc1OCC(=O)Nc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B06 compound treatment 83840.0 31700.0 1.83 65880.0 1050.0 0.08 1.3531 0.7371 1150838 TimTec1_007772 CCc1cccc(C)c1NC(=O)COC(=O)C2CN(C(=O)C2)c3ccc(OC(C)C)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B07 compound treatment 85680.0 33500.0 1.94 69320.0 4490.0 0.34 1.6126 0.8185 3086815 TimTec1_007773 O=C(NCCN1CCCCC1)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B08 compound treatment 81680.0 29500.0 1.71 60560.0 -4270.0 -0.32 0.9799 0.5634 3211973 TimTec1_007774 CCCNC(=O)C1CCN(CC1)C(=O)c2ccccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B09 compound treatment 80640.0 28500.0 1.65 63160.0 -1670.0 -0.13 1.0764 0.651 1292787 TimTec1_007775 O=C(COc1ccccc1)N2CCN(Cc3ccccn3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B10 compound treatment 70720.0 18500.0 1.07 51640.0 -13200.0 -1.0 0.0534 0.0364 1281347 TimTec1_007776 COC(=O)Cn1cnc2sc(cc2c1=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B11 compound treatment 83080.0 30900.0 1.79 59680.0 -5150.0 -0.39 0.9901 0.5405 3086816 TimTec1_007777 O=C(NCCC1=CCCCC1)c2cnsn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B12 compound treatment 92320.0 40100.0 2.33 74280.0 9450.0 0.72 2.1501 0.8838 1285189 TimTec1_007778 CCOC(=O)c1nc2sc3CC(C)CCc3c2c(=O)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B13 compound treatment 64000.0 11800.0 0.68 57600.0 -7230.0 -0.55 0.0971 0.1108 3211974 TimTec1_007779 Clc1ccc(CNc2ccc3OCCOc3c2)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B14 compound treatment 67720.0 15500.0 0.9 58200.0 -6630.0 -0.5 0.2816 0.2733 1677544 TimTec1_007780 O=C(Cn1cnc2sc3CCCCc3c2c1=O)NCc4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B15 compound treatment 77040.0 24900.0 1.44 65040.0 210.0 0.02 1.0296 0.7149 3211975 TimTec1_007781 CCCOC(=O)Cn1cnc2sc(C)c(C)c2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B16 compound treatment 64360.0 12200.0 0.71 57480.0 -7350.0 -0.56 0.1054 0.1174 3211976 TimTec1_007782 CCC(Oc1ccccc1)C(=O)NCc2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B17 compound treatment 56840.0 4660.0 0.27 50760.0 -14100.0 -1.07 -0.5623 -0.5118 3086817 TimTec1_007783 COC(=O)c1cc(on1)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B18 compound treatment 58720.0 6540.0 0.38 62680.0 -2150.0 -0.16 0.1527 0.3705 1678690 TimTec1_007784 COc1ccc(cc1)c2csc3ncn(CC=C)c(=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B19 compound treatment 55760.0 3580.0 0.21 55600.0 -9230.0 -0.7 -0.3475 -0.4769 1600545 TimTec1_007785 COc1ccc(OCC(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B20 compound treatment 67720.0 15500.0 0.9 49080.0 -15800.0 -1.19 -0.2065 -0.1382 1255438 TimTec1_007786 Clc1ccc(CNC(=O)c2cc3ccccc3oc2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B21 compound treatment 44800.0 -7380.0 -0.43 56080.0 -8750.0 -0.66 -0.7708 -0.9776 3086818 TimTec1_007787 CCN1C=C(C(C(=C1)C(=O)OC)c2ccc(Cl)cc2)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B22 compound treatment 65080.0 12900.0 0.75 79600.0 14800.0 1.12 1.3189 0.9808 3086862 TimTec1_007788 CCc1cccc(CC)c1NC(=O)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B23 mock treatment 65840.0 13700.0 0.79 75160.0 10300.0 0.78 1.1124 1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 B24 mock treatment 59320.0 7140.0 0.41 77240.0 12400.0 0.94 0.9566 0.932 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C01 compound treatment 82480.0 30300.0 1.76 67840.0 3010.0 0.23 1.4023 0.7922 1318228 TimTec1_007789 Cc1cc(C)c(NC(=O)c2ccncc2)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C02 compound treatment 77920.0 25700.0 1.49 74640.0 9810.0 0.74 1.5794 0.9482 3086863 TimTec1_007790 Clc1ccc(c2csc(Nc3ncccn3)n2)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C03 compound treatment 82880.0 30700.0 1.78 73240.0 8410.0 0.64 1.7077 0.904 3086864 TimTec1_007791 CCCN1CC2(OC3C=C2)C(C3C(=O)O)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C04 compound treatment 80600.0 28400.0 1.65 64560.0 -270.0 -0.02 1.1497 0.6983 3086865 TimTec1_007792 OCCNc1nc(nc2ccccc12)N3CCN(CC3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C05 compound treatment 72760.0 20600.0 1.19 53440.0 -11400.0 -0.86 0.2333 0.1586 3086866 TimTec1_007793 CC(C)(C)NC(=O)c1cccc(NC(=O)Cc2cccs2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C06 compound treatment 79400.0 27200.0 1.58 65560.0 730.0 0.06 1.1541 0.7314 3086867 TimTec1_007794 OC1=C(C(N(Cc2ccccc2)C1=O)c3cccnc3)C(=O)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C07 compound treatment 11880.0 -40300.0 -2.34 11240.0 -53600.0 -4.06 -4.5195 -0.9656 1136666 TimTec1_007795 O=C1OCCC1Sc2cccc3cccnc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C08 compound treatment 78720.0 26500.0 1.54 64280.0 -550.0 -0.04 1.0577 0.6877 3212034 TimTec1_007796 CC(C)C(=O)Nc1nnc(s1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C09 compound treatment 9000.0 -43200.0 -2.5 8080.0 -56800.0 -4.3 -4.8066 -0.9669 3212035 TimTec1_007797 CCC(=O)N1CCN(CC1)c2ccc(NC(=O)COc3ccc(Cl)cc3Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C10 compound treatment 75400.0 23200.0 1.35 58360.0 -6470.0 -0.49 0.6048 0.4225 3086868 TimTec1_007798 COc1ccc2oc(=O)c(cc2c1)C(=O)NC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C11 compound treatment 47320.0 -4860.0 -0.28 38560.0 -26300.0 -1.99 -1.6053 -0.7993 3212036 TimTec1_007799 Cc1cc(C)c(C(=O)N)c(NCCc2ccccc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C12 compound treatment 67840.0 15700.0 0.91 53320.0 -11500.0 -0.87 0.0253 0.0202 1098140 TimTec1_007800 O=S(=O)(N1CN2CCN(C2)C1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C13 compound treatment 68920.0 16700.0 0.97 58920.0 -5910.0 -0.45 0.3693 0.3459 3212037 TimTec1_007801 Clc1ccccc1NC(=O)Cn2c(=O)oc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C14 compound treatment 81640.0 29500.0 1.71 65800.0 970.0 0.07 1.2587 0.7368 1203605 TimTec1_007802 CCC(=O)OC1(CC(C)N(C)CC1C)c2cccc(C)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C15 compound treatment 70720.0 18500.0 1.07 62680.0 -2150.0 -0.16 0.6443 0.5932 3212038 TimTec1_007803 COC(=O)Cn1cc(C#N)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C16 compound treatment 35080.0 -17100.0 -0.99 42080.0 -22800.0 -1.72 -1.9184 -0.9656 3086869 TimTec1_007804 CC(C)C(=O)Nc1ccc2nn(nc2c1)c3ccc(C)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C17 compound treatment 61720.0 9540.0 0.55 65680.0 850.0 0.06 0.4362 0.7842 1546820 TimTec1_007805 O=C(N1CCN(CC1)C2CCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C18 compound treatment 30200.0 -22000.0 -1.27 46440.0 -18400.0 -1.39 -1.8849 -0.999 1186833 TimTec1_007806 NC(=O)c1c(NC(=O)c2ccccc2)sc3CCCc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C19 compound treatment 57680.0 5500.0 0.32 79520.0 14700.0 1.11 1.0114 0.8745 1584588 TimTec1_007807 CC1CCCN(C1)C(=O)C2(CCC3(C)C(=O)C2)C3(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C20 compound treatment 53560.0 1380.0 0.08 73440.0 8610.0 0.65 0.5172 0.7877 1147418 TimTec1_007808 Clc1cc(Cl)cc(NC(=O)COC(=O)C2CCCO2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C21 compound treatment 23120.0 -29100.0 -1.68 24200.0 -40600.0 -3.08 -3.3654 -0.9598 1448442 TimTec1_007809 COc1ccc(CNCC2COc3ccccc3O2)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C22 compound treatment 49040.0 -3140.0 -0.18 67320.0 2490.0 0.19 0.0045 0.0171 1413356 TimTec1_007810 OC(=O)c1ccc(cc1O)n2cccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C23 mock treatment 67800.0 15600.0 0.9 77760.0 12900.0 0.98 1.3318 0.9992 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 C24 mock treatment 53880.0 1700.0 0.1 63680.0 -1150.0 -0.09 0.0079 0.0605 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D01 compound treatment 85240.0 33100.0 1.92 72680.0 7850.0 0.59 1.7744 0.8849 1452042 TimTec1_007811 Clc1cccc(OCCN2CCCC2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D02 compound treatment 61000.0 8820.0 0.51 56600.0 -8230.0 -0.62 -0.0793 -0.0985 3212039 TimTec1_007812 COc1ccc(cc1)N2CC(CC2=O)C(=O)OC(C)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D03 compound treatment 69440.0 17300.0 1.0 58000.0 -6830.0 -0.52 0.3414 0.3033 3212040 TimTec1_007813 O=C(CS(=O)(=O)Cc1ccccc1)N2CCCc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D04 compound treatment 62440.0 10300.0 0.59 47760.0 -17100.0 -1.29 -0.4935 -0.347 1438278 TimTec1_007814 CN(C1CCCCC1)C(=O)c2cc3nc(cc(C)n3n2)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D05 compound treatment 78400.0 26200.0 1.52 53560.0 -11300.0 -0.85 0.4708 0.2703 3212041 TimTec1_007815 O=C(NCCC1=CCCCC1)C2COc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D06 compound treatment 72160.0 20000.0 1.16 57240.0 -7590.0 -0.57 0.4121 0.319 3212042 TimTec1_007816 Cc1cccc(NC(=O)C2CN(C(=O)C2)c3ccccc3)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D07 compound treatment 77160.0 25000.0 1.45 67920.0 3090.0 0.23 1.1886 0.8109 3086870 TimTec1_007817 CC(=O)Nc1ccc(cc1)c2nc3ccccc3c(=O)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D08 compound treatment 68400.0 16200.0 0.94 51080.0 -13800.0 -1.04 -0.0716 -0.0511 1679774 TimTec1_007818 O=C(Nc1ccc2oc(nc2c1)c3ccncc3)c4ccco4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D09 compound treatment 61400.0 9220.0 0.53 48440.0 -16400.0 -1.24 -0.4997 -0.37 3086871 TimTec1_007819 c1nnnn1c2ccccc2c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D10 compound treatment 25400.0 -26800.0 -1.55 17360.0 -47500.0 -3.59 -3.6381 -0.9295 1121757 TimTec1_007820 CC(C)OC(=O)C(C)n1cnc2sc(cc2c1=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D11 compound treatment 79360.0 27200.0 1.57 59960.0 -4870.0 -0.37 0.8527 0.5273 3086872 TimTec1_007821 COC(=O)c1cccc(NC(=O)C2COc3ccccc3O2)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D12 compound treatment 58320.0 6140.0 0.36 53400.0 -11400.0 -0.87 -0.3604 -0.3853 3212043 TimTec1_007822 Clc1ccc(cc1)c2csc3ncn(CC=C)c(=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D13 compound treatment 57840.0 5660.0 0.33 58800.0 -6030.0 -0.46 -0.091 -0.162 3086873 TimTec1_007823 COc1cc(CNc2ccc3OCCOc3c2)ccc1OCC(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D14 compound treatment 58760.0 6580.0 0.38 66120.0 1290.0 0.1 0.3385 0.8605 1309609 TimTec1_007824 Cc1sc2ncn(CC(=O)Nc3ccccc3)c(=O)c2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D15 compound treatment 41400.0 -10800.0 -0.62 46000.0 -18800.0 -1.43 -1.4496 -0.9315 1697737 TimTec1_007825 O=c1n(CCc2ccccc2)cnc3sc4CCCCc4c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D16 compound treatment 54040.0 1860.0 0.11 64320.0 -510.0 -0.04 0.0487 0.4266 1880627 TimTec1_007826 COc1ccc(NC(=O)C2CCCO2)c(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D17 compound treatment 54800.0 2620.0 0.15 69480.0 4650.0 0.35 0.3561 0.9291 3212044 TimTec1_007827 OC1=C(C(N(CCc2c[nH]c3ccccc23)C1=O)c4ccccn4)C(=O)c5ccccc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D18 compound treatment 26120.0 -26100.0 -1.51 42680.0 -22200.0 -1.68 -2.2533 -0.9986 3086874 TimTec1_007828 Cc1ccc(cc1C)c2csc3nc[nH]c(=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D19 compound treatment 18280.0 -33900.0 -1.96 8320.0 -56500.0 -4.28 -4.4136 -0.9377 1471052 TimTec1_007829 CC(C)(C)C(=O)Nc1ccc(NC(=O)c2ccco2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D20 compound treatment 34480.0 -17700.0 -1.03 45240.0 -19600.0 -1.48 -1.7738 -0.9838 3086875 TimTec1_007830 Nc1c(c2nc3ccccc3s2)c4nc(C#N)c(C#N)nc4n1c5ccc(Cl)cc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D21 compound treatment 51040.0 -1140.0 -0.07 67480.0 2650.0 0.2 0.095 0.4496 3212045 TimTec1_007831 COC(=O)C1=CN(C=C(C1c2cccs2)C(=O)OC)c3ccc(F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D22 compound treatment 38680.0 -13500.0 -0.78 41560.0 -23300.0 -1.76 -1.7987 -0.9333 3212046 TimTec1_007832 CCCNC(=O)c1ccccc1NC(=O)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D23 mock treatment 56200.0 4020.0 0.23 40720.0 -24100.0 -1.82 -1.1259 -0.612 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 D24 mock treatment 61120.0 8940.0 0.52 51760.0 -13100.0 -0.99 -0.3335 -0.2986 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E01 compound treatment 81440.0 29300.0 1.7 61440.0 -3390.0 -0.26 1.0171 0.5933 3086876 TimTec1_007833 O=C(CSc1nncc2ccccc12)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E02 compound treatment 56080.0 3900.0 0.23 44680.0 -20200.0 -1.53 -0.9189 -0.596 3212047 TimTec1_007834 C(Cc1ccccc1)Nc2nc(cs2)c3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E03 compound treatment 52320.0 136.0 0.01 36040.0 -28800.0 -2.18 -1.5354 -0.7045 1261375 TimTec1_007835 CC1CCCCN1C(=O)c2c(C)onc2c3ccccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E04 compound treatment 74760.0 22600.0 1.31 63680.0 -1150.0 -0.09 0.8634 0.6586 3212048 TimTec1_007836 Cc1cc2c(=O)[nH]c(Cc3ccccc3)nc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E05 compound treatment 82520.0 30300.0 1.76 62920.0 -1910.0 -0.14 1.1406 0.6468 3086877 TimTec1_007837 OC(=O)CCC(=O)N1CCNC(=O)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E06 compound treatment 74480.0 22300.0 1.29 57280.0 -7550.0 -0.57 0.5093 0.3606 3212049 TimTec1_007838 C(Cn1c(nc2ccccc12)N3CCCC3)N4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E07 compound treatment 17320.0 -34900.0 -2.02 16560.0 -48300.0 -3.65 -4.0119 -0.9609 3212050 TimTec1_007839 COc1ccccc1NC(=O)CCSc2cccc3cccnc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E08 compound treatment 80160.0 28000.0 1.62 62440.0 -2390.0 -0.18 1.0182 0.6243 1217846 TimTec1_007840 COc1ccccc1C(CC(=O)O)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E09 compound treatment 68080.0 15900.0 0.92 60200.0 -4630.0 -0.35 0.4034 0.4094 3212051 TimTec1_007841 CC(Sc1ccc(C)cc1)C(=O)N2CCC(CC2)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E10 compound treatment 30960.0 -21200.0 -1.23 27960.0 -36900.0 -2.79 -2.8429 -0.9322 1340156 TimTec1_007842 CC(OC(=O)c1cc(C)nc2ccccc12)C(=O)c3ccc(C)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E11 compound treatment 73560.0 21400.0 1.24 62320.0 -2510.0 -0.19 0.7414 0.5917 3212052 TimTec1_007843 CCOc1ccc(cc1)C2C3=C(CCCC3=O)N(CC)C4=C2C(=O)CCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E12 compound treatment 60880.0 8700.0 0.5 68280.0 3450.0 0.26 0.5409 0.9532 3086878 TimTec1_007844 CC(=O)N1CCn2c1nc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E13 compound treatment 54360.0 2180.0 0.13 68560.0 3730.0 0.28 0.2888 0.934 3212053 TimTec1_007845 Cc1cccc(NC(=O)Cn2cnc3ccccc3c2=O)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E14 compound treatment 42720.0 -9460.0 -0.55 67200.0 2370.0 0.18 -0.2609 -0.4522 1631753 TimTec1_007846 CC(C)N(C(=O)Cn1nnc2ccccc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E15 compound treatment 57680.0 5500.0 0.32 64240.0 -590.0 -0.04 0.1936 0.602 3212054 TimTec1_007847 CN(C)C(=O)C1=C(C)NC(=O)NC1c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E16 compound treatment 39600.0 -12600.0 -0.73 57360.0 -7470.0 -0.57 -0.9154 -0.9921 3212055 TimTec1_007848 O=C(Nc1ccc2oc(nc2c1)c3cccnc3)c4cccs4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E17 compound treatment 49720.0 -2460.0 -0.14 75920.0 11100.0 0.84 0.4926 0.5786 1557418 TimTec1_007849 CN(CC(=O)O)S(=O)(=O)c1ccc2oc3ccccc3c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E18 compound treatment 51000.0 -1180.0 -0.07 79200.0 14400.0 1.09 0.7206 0.6612 3212115 TimTec1_007850 CC(c1ccccc1F)n2cc(nn2)C(=O)NCCCn3ccc(C)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E19 compound treatment 43400.0 -8780.0 -0.51 62600.0 -2230.0 -0.17 -0.4792 -0.8938 3086879 TimTec1_007851 Cc1ccc(cc1)c2csc(CC(=O)N)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E20 compound treatment 19680.0 -32500.0 -1.88 16320.0 -48500.0 -3.67 -3.9281 -0.9519 3212116 TimTec1_007852 NC1=C(C(=O)CN1c2ccccc2)c3nc4ccccc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E21 compound treatment 15520.0 -36700.0 -2.12 32040.0 -32800.0 -2.48 -3.2571 -0.997 3086880 TimTec1_007853 FC(F)(F)c1cccc(NC(=O)CC2COc3ccccc3O2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E22 compound treatment 55880.0 3700.0 0.21 63480.0 -1350.0 -0.1 0.0792 0.3337 3212117 TimTec1_007854 Cc1cc(Nc2ccc(O)cc2)c3ccccc3n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E23 mock treatment 67840.0 15700.0 0.91 78800.0 14000.0 1.06 1.3891 0.9971 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 E24 mock treatment 63600.0 11400.0 0.66 63840.0 -990.0 -0.07 0.4147 0.623 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F01 compound treatment 44200.0 -7980.0 -0.46 38480.0 -26400.0 -1.99 -1.7374 -0.8486 3212118 TimTec1_007855 Fc1cnc(Nc2ccc3OCOc3c2)nc1Nc4ccc5OCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F02 compound treatment 80800.0 28600.0 1.66 64440.0 -390.0 -0.03 1.1515 0.6944 1530427 TimTec1_007856 O=S1(=O)CC(C(C1)N2CCCCC2)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F03 compound treatment 82000.0 29800.0 1.73 61120.0 -3710.0 -0.28 1.0229 0.5845 3212119 TimTec1_007857 O=C(CS(=O)(=O)Cc1ccccc1)Nc2ccc3OCCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F04 compound treatment 63200.0 11000.0 0.64 46600.0 -18200.0 -1.38 -0.5244 -0.3449 1445255 TimTec1_007858 Cc1sc2ncn(Cc3ccccc3C)c(=O)c2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F05 compound treatment 68280.0 16100.0 0.93 46120.0 -18700.0 -1.42 -0.342 -0.2017 3212120 TimTec1_007859 CC(C)(C)c1ccc(cc1)C(=O)NCCCn2ccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F06 compound treatment 66600.0 14400.0 0.84 54680.0 -10200.0 -0.77 0.0473 0.0417 3086881 TimTec1_007860 O=C(Nc1nc2ccccc2s1)C3CN(C(=O)C3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F07 compound treatment 32120.0 -20100.0 -1.16 26280.0 -38600.0 -2.92 -2.8853 -0.9186 1530603 TimTec1_007861 COc1ccc(cc1)c2nc3cc(Cl)ccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F08 compound treatment 82760.0 30600.0 1.77 67200.0 2370.0 0.18 1.3795 0.7748 3212121 TimTec1_007862 CCN1CCN(CC1)c2ccc(NC(=O)C(C)C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F09 compound treatment 73000.0 20800.0 1.21 65520.0 690.0 0.05 0.8897 0.737 3086882 TimTec1_007863 Cc1cc(NC(=O)COC(=O)c2ccccn2)ccc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F10 compound treatment 67320.0 15100.0 0.88 63920.0 -910.0 -0.07 0.5714 0.6496 1672981 TimTec1_007864 CCOC(=O)c1sc2ncn(C(C)C(=O)OCc3ccccc3)c(=O)c2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F11 compound treatment 66320.0 14100.0 0.82 71200.0 6370.0 0.48 0.9201 0.9681 3086883 TimTec1_007865 CN1CCCC(C1)OC(=O)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F12 compound treatment 53480.0 1300.0 0.08 73400.0 8570.0 0.65 0.5118 0.7837 3212122 TimTec1_007866 NC(=O)c1cnn2c(cc(nc12)c3ccc(F)cc3)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F13 compound treatment 48720.0 -3460.0 -0.2 70240.0 5410.0 0.41 0.1477 0.3238 1446085 TimTec1_007867 O=C(CCc1ccccc1)NCCc2nc3ccccc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F14 compound treatment 48400.0 -3780.0 -0.22 70800.0 5970.0 0.45 0.1645 0.3276 3212123 TimTec1_007868 CCOC(=O)c1cnc2ccc(F)cc2c1NCc3cccnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F15 compound treatment 51440.0 -744.0 -0.04 71400.0 6570.0 0.5 0.3212 0.6434 1185524 TimTec1_007869 COc1ccc(CCNc2nccc(=O)[nH]2)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F16 compound treatment 55120.0 2940.0 0.17 73480.0 8650.0 0.65 0.5833 0.8622 3086884 TimTec1_007870 O=C(Nc1nncs1)C2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F17 compound treatment 58800.0 6620.0 0.38 80520.0 15700.0 1.19 1.1108 0.8901 3086934 TimTec1_007871 Nc1cc(ccc1NCC2CCCO2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F18 compound treatment 56160.0 3980.0 0.23 78960.0 14100.0 1.07 0.9192 0.8401 1657481 TimTec1_007872 Cc1sc2ncnc(NCC(=O)O)c2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F19 compound treatment 54800.0 2620.0 0.15 62800.0 -2030.0 -0.15 -0.0015 -0.0068 1451450 TimTec1_007873 CC1CC(Nc2ccc(C)cc2)c3ccc(C)cc3N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F20 compound treatment 64080.0 11900.0 0.69 88080.0 23300.0 1.76 1.7318 0.9163 3086935 TimTec1_007874 COc1ccc2ncc(C(=O)NC3CCCC3)c(Cl)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F21 compound treatment 70080.0 17900.0 1.04 74000.0 9170.0 0.69 1.224 0.981 3086936 TimTec1_007875 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(Br)cc3)C(=O)N4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F22 compound treatment 72360.0 20200.0 1.17 84040.0 19200.0 1.45 1.8548 0.9941 3086937 TimTec1_007876 CCOC(=O)c1cc(CN2CCOCC2)c(C)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F23 mock treatment 76040.0 23900.0 1.38 84560.0 19700.0 1.49 2.0334 0.9993 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 F24 mock treatment 64160.0 12000.0 0.69 69040.0 4210.0 0.32 0.716 0.9377 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G01 compound treatment 80600.0 28400.0 1.65 67600.0 2770.0 0.21 1.3124 0.7908 1620505 TimTec1_007877 CCN1CC(C)C(O)(CC1C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G02 compound treatment 48520.0 -3660.0 -0.21 29920.0 -34900.0 -2.64 -2.0186 -0.7615 3086938 TimTec1_007878 CN(c1nc(cs1)c2cccnc2)c3ccc(O)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G03 compound treatment 46960.0 -5220.0 -0.3 29360.0 -35500.0 -2.68 -2.1125 -0.7819 1423365 TimTec1_007879 COc1ccc(CC(=O)Nc2nccs2)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G04 compound treatment 75200.0 23000.0 1.33 48440.0 -16400.0 -1.24 0.0657 0.0361 1877456 TimTec1_007880 COc1cc(OC)c(cc1OC)C(=O)N2CCN(CC2)c3ccccc3F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G05 compound treatment 75560.0 23400.0 1.35 53920.0 -10900.0 -0.83 0.3737 0.2356 3086939 TimTec1_007881 CCOC(=O)Cn1cnc2ccccc2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G06 compound treatment 73000.0 20800.0 1.21 55240.0 -9590.0 -0.73 0.3395 0.2412 3212124 TimTec1_007882 CC(c1ccc(C)cc1)n2cc(nn2)C(=O)NCC3CCCO3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G07 compound treatment 75960.0 23800.0 1.38 57520.0 -7310.0 -0.55 0.5828 0.3926 3086940 TimTec1_007883 Cn1nnc2cc(ccc12)C(=O)NC3CC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G08 compound treatment 81480.0 29300.0 1.7 63920.0 -910.0 -0.07 1.1515 0.6779 3212125 TimTec1_007884 CC(C(=O)NCCN1CCOCC1)(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G09 compound treatment 69880.0 17700.0 1.03 65960.0 1130.0 0.09 0.7855 0.7634 3086941 TimTec1_007885 CC(Sc1ccc(Cl)cc1)C(=O)NCc2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G10 compound treatment 74720.0 22500.0 1.31 71720.0 6890.0 0.52 1.292 0.919 1356547 TimTec1_007886 CC(OC(=O)c1ccc2ccccc2n1)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G11 compound treatment 51360.0 -824.0 -0.05 55000.0 -9830.0 -0.74 -0.5599 -0.7509 3086942 TimTec1_007887 O=C(Cn1c(=O)sc2ccccc12)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G12 compound treatment 44920.0 -7260.0 -0.42 61840.0 -2990.0 -0.23 -0.4576 -0.9577 3212126 TimTec1_007888 OC(=O)CCc1c(cc2ccccn12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G13 compound treatment 37520.0 -14700.0 -0.85 51960.0 -12900.0 -0.97 -1.2896 -0.9977 3086943 TimTec1_007889 Clc1ccc(cc1)C2(CCCC2)C(=O)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G14 compound treatment 36520.0 -15700.0 -0.91 53640.0 -11200.0 -0.85 -1.2406 -0.9994 3212127 TimTec1_007890 O(c1ccccc1)c2ccc(cc2)n3cnnn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G15 compound treatment 47640.0 -4540.0 -0.26 68320.0 3490.0 0.26 6.0E-4 0.0017 3212128 TimTec1_007891 CCCNC(=O)C1CCN(CC1)C(=O)c2ccc(cc2)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G16 compound treatment 45800.0 -6380.0 -0.37 52000.0 -12800.0 -0.97 -0.9482 -0.9125 3086944 TimTec1_007892 CC(C)C(=O)Nc1ccc(cc1)c2nc3cc(Cl)ccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G17 compound treatment 34240.0 -17900.0 -1.04 38520.0 -26300.0 -1.99 -2.1433 -0.9541 1141486 TimTec1_007893 COc1ccc(cc1)c2csc(n2)C(=C3CCCCC3)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G18 compound treatment 58600.0 6420.0 0.37 69000.0 4170.0 0.32 0.4861 0.9967 3086945 TimTec1_007894 CC(c1ccc(F)cc1)n2cc(nn2)C(=O)NCCN(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G19 compound treatment 57640.0 5460.0 0.32 67520.0 2690.0 0.2 0.3675 0.9774 1848000 TimTec1_007895 Cc1cccc(NC(=O)CSc2ccccn2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G20 compound treatment 71760.0 19600.0 1.13 78840.0 14000.0 1.06 1.5519 0.9994 1391065 TimTec1_007896 OC(=O)C1CCCN1c2ncnc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G21 compound treatment 58880.0 6700.0 0.39 68560.0 3730.0 0.28 0.474 0.9878 3086946 TimTec1_007897 CCOc1ccc(cc1)c2cnc(N)s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G22 compound treatment 63480.0 11300.0 0.65 77560.0 12700.0 0.96 1.1441 0.9822 1231110 TimTec1_007898 Clc1ccc(cc1)C(=O)Cn2cnc3ccccc3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G23 mock treatment 66280.0 14100.0 0.82 74760.0 9930.0 0.75 1.109 0.9991 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 G24 mock treatment 55400.0 3220.0 0.19 53960.0 -10900.0 -0.82 -0.45 -0.5335 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H01 compound treatment 28600.0 -23600.0 -1.37 19920.0 -44900.0 -3.4 -3.3699 -0.9198 3212129 TimTec1_007899 Oc1cccc(Nc2nc(NCC3CCCO3)c4ccccc4n2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H02 compound treatment 76920.0 24700.0 1.43 60000.0 -4830.0 -0.37 0.7549 0.5104 1270407 TimTec1_007900 CN(C1CCS(=O)(=O)C1)C(=O)c2ccccc2C(=O)N(C)C3CCS(=O)(=O)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H03 compound treatment 79160.0 27000.0 1.56 58120.0 -6710.0 -0.51 0.746 0.4539 3086947 TimTec1_007901 CCOC(=O)c1ccc2nc(NC(=O)COC(=O)c3ccnn3C)sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H04 compound treatment 61120.0 8940.0 0.52 40040.0 -24800.0 -1.88 -0.9608 -0.4936 1714833 TimTec1_007902 COC(=O)c1sc2ncn(Cc3ccc(C)cc3)c(=O)c2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H05 compound treatment 80480.0 28300.0 1.64 59920.0 -4910.0 -0.37 0.8964 0.5333 1510758 TimTec1_007903 Fc1cccc(c1)C(=O)OCCN2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H06 compound treatment 67160.0 15000.0 0.87 56200.0 -8630.0 -0.65 0.1516 0.1396 1201896 TimTec1_007904 COc1cccc(c1)C2C3=C(CC(C)(C)CC3=O)NC4=C2C(=O)CC(C)(C)C4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H07 compound treatment 65120.0 12900.0 0.75 63200.0 -1630.0 -0.12 0.4427 0.5829 1221015 TimTec1_007905 Clc1ccc(SCC(=O)Nc2ccc(NC(=O)c3ccco3)cc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H08 compound treatment 59680.0 7500.0 0.43 62800.0 -2030.0 -0.15 0.1985 0.4308 3212130 TimTec1_007906 COc1ccc(NC(=O)c2ccco2)cc1NC(=O)Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H09 compound treatment 18840.0 -33300.0 -1.93 27280.0 -37600.0 -2.84 -3.3759 -0.9823 3212131 TimTec1_007907 COC(=O)c1c(C)n(Cc2ccccc2)c3ccc(O)cc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H10 compound treatment 53760.0 1580.0 0.09 62600.0 -2230.0 -0.17 -0.0548 -0.2854 1197980 TimTec1_007908 CC(C(=O)O)n1cnc2sc(C)c(C)c2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H11 compound treatment 39520.0 -12700.0 -0.73 59200.0 -5630.0 -0.43 -0.8202 -0.9666 3212132 TimTec1_007909 Cn1c(nc2cc(N)ccc12)c3ccc4nc([nH]c4c3)c5ccc(N)cc5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H12 compound treatment 49200.0 -2980.0 -0.17 69840.0 5010.0 0.38 0.1459 0.3501 3086948 TimTec1_007910 OC(=O)CCCn1nc(c2CCCCCc21)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H13 compound treatment 20840.0 -31300.0 -1.82 37760.0 -27100.0 -2.05 -2.733 -0.9982 1451319 TimTec1_007911 NC(=O)c1cc(sc1NC(=O)c2ccco2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H14 compound treatment 51360.0 -824.0 -0.05 68520.0 3690.0 0.28 0.1638 0.5779 3086949 TimTec1_007912 CC1=C(C(c2cccnc2)n3nnnc3N1)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H15 compound treatment 49400.0 -2780.0 -0.16 65520.0 690.0 0.05 -0.0771 -0.4549 1397485 TimTec1_007913 CC1CN(Cc2ccc(C#N)cc2Cl)CC(C)O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H16 compound treatment 37400.0 -14800.0 -0.86 50480.0 -14400.0 -1.09 -1.3737 -0.9931 3086950 TimTec1_007914 Cc1nn(c2ccc(C)c(C)c2)c3oc(=O)cc(C)c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H17 compound treatment 53720.0 1540.0 0.09 72800.0 7970.0 0.6 0.4895 0.8027 3212198 TimTec1_007915 Clc1ccc(cc1)N2C(=O)CC(SCc3nc4ccccc4[nH]3)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H18 compound treatment 40600.0 -11600.0 -0.67 45000.0 -19800.0 -1.5 -1.5359 -0.9341 1414950 TimTec1_007916 CCc1ccc(cc1)c2csc3ncn(CC(=O)N)c(=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H19 compound treatment 46480.0 -5700.0 -0.33 80080.0 15300.0 1.15 0.5826 0.4852 1788367 TimTec1_007917 Cc1cc(C)nc(NS(=O)(=O)c2ccc(cc2)n3cccc3)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H20 compound treatment 66040.0 13900.0 0.8 66240.0 1410.0 0.11 0.6431 0.7941 3212199 TimTec1_007918 COc1ccc2ncc(C(=O)N3CCOCC3)c(Cl)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H21 compound treatment 47800.0 -4380.0 -0.25 78080.0 13300.0 1.0 0.5296 0.5119 3086951 TimTec1_007919 OC(=O)C1CC(=O)N=C(Nc2nc3ccccc3s2)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H22 compound treatment 64080.0 11900.0 0.69 76120.0 11300.0 0.85 1.0917 0.9943 3212200 TimTec1_007920 CC(C)(C)NC(=O)c1ccc2snnc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H23 mock treatment 55280.0 3100.0 0.18 82800.0 18000.0 1.36 1.0887 0.7935 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 H24 mock treatment 51640.0 -544.0 -0.03 81520.0 16700.0 1.26 0.871 0.6893 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I01 compound treatment 87080.0 34900.0 2.02 61360.0 -3470.0 -0.26 1.2439 0.6101 3086952 TimTec1_007921 CC1CN(Cc2ccccc2)C(C)CC1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I02 compound treatment 76160.0 24000.0 1.39 52160.0 -12700.0 -0.96 0.3041 0.1802 1162910 TimTec1_007922 CNC(=O)c1c(O)c2cccc3CCCn(c1=O)c32 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I03 compound treatment 84280.0 32100.0 1.86 51760.0 -13100.0 -0.99 0.6154 0.2921 1008293 TimTec1_007923 CCN(CC)C(=O)c1ccc2OCOc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I04 compound treatment 82720.0 30500.0 1.77 60080.0 -4750.0 -0.36 0.9968 0.5521 1846984 TimTec1_007924 CCc1nnc(NC(=O)c2sc3nc4CCCCc4cc3c2N)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I05 compound treatment 20360.0 -31800.0 -1.84 13520.0 -51300.0 -3.88 -4.0501 -0.942 1303764 TimTec1_007925 Brc1ccc2ncnc(NCC3CCCO3)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I06 compound treatment 69560.0 17400.0 1.01 55480.0 -9350.0 -0.71 0.2114 0.1718 3086953 TimTec1_007926 CC(c1ccc(C)cc1)n2cc(nn2)C(=O)NCc3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I07 compound treatment 74040.0 21900.0 1.27 57440.0 -7390.0 -0.56 0.4999 0.3611 3212201 TimTec1_007927 Cn1nnc2cc(ccc12)C(=O)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I08 compound treatment 67520.0 15300.0 0.89 62760.0 -2070.0 -0.16 0.5175 0.5736 3212202 TimTec1_007928 CC(C(=O)NCCCn1ccnc1)(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I09 compound treatment 60560.0 8380.0 0.49 63440.0 -1390.0 -0.11 0.2688 0.5412 3086954 TimTec1_007929 CCC(=O)c1cn(CC(=O)NC2CCCCC2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I10 compound treatment 46640.0 -5540.0 -0.32 63360.0 -1470.0 -0.11 -0.3058 -0.8996 1690696 TimTec1_007930 COc1ccc2oc(=O)c(cc2c1)C(=O)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I11 compound treatment 44640.0 -7540.0 -0.44 57840.0 -6990.0 -0.53 -0.6832 -0.9955 3086955 TimTec1_007931 O=S1(=O)N=C(Nc2nc(cs2)c3ccccc3)c4ccccc41 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I12 compound treatment 26240.0 -25900.0 -1.5 36440.0 -28400.0 -2.15 -2.5824 -0.9847 3212203 TimTec1_007932 C(c1ccccc1)n2c(nc3ccccc23)C4CC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I13 compound treatment 46920.0 -5260.0 -0.3 68120.0 3290.0 0.25 -0.0396 -0.1005 1152223 TimTec1_007933 COc1ccc(NC(=O)c2ccco2)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I14 compound treatment 41320.0 -10900.0 -0.63 69040.0 4210.0 0.32 -0.2197 -0.3115 3212204 TimTec1_007934 CCOC(=O)C1=C(C)N(CC=C)C(=O)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I15 compound treatment 43680.0 -8500.0 -0.49 61280.0 -3550.0 -0.27 -0.5384 -0.9594 3212205 TimTec1_007935 COc1cc(C#N)ccc1OCc2nc(no2)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I16 compound treatment 41520.0 -10700.0 -0.62 54120.0 -10700.0 -0.81 -1.0101 -0.991 3086956 TimTec1_007936 CCC(=O)Nc1ccc(cc1)c2cc3ccccc3oc2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I17 compound treatment 58960.0 6780.0 0.39 75720.0 10900.0 0.82 0.8605 0.9425 1481021 TimTec1_007937 CC1(C)C2CCC(C2)(C(=O)N3CCOCC3)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I18 compound treatment 46920.0 -5260.0 -0.3 53480.0 -11400.0 -0.86 -0.8231 -0.9029 1184905 TimTec1_007938 COC(=O)c1ccc(Nc2ncnc3ccccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I19 compound treatment 61480.0 9300.0 0.54 67080.0 2250.0 0.17 0.5013 0.8874 1216188 TimTec1_007939 CC(C)c1cccc(C(C)C)c1NC(=O)Cc2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I20 compound treatment 51240.0 -944.0 -0.05 55960.0 -8870.0 -0.67 -0.5134 -0.7622 3212206 TimTec1_007940 O=C(OCCNc1nc(nc2ccccc12)c3ccccc3)c4ccncc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I21 compound treatment 72800.0 20600.0 1.19 71520.0 6690.0 0.51 1.2027 0.927 3086957 TimTec1_007941 CC(C)NC(=O)C1(CCOCC1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I22 compound treatment 54760.0 2580.0 0.15 63160.0 -1670.0 -0.13 0.0162 0.0826 3212207 TimTec1_007942 CC(c1ccccc1)n2cnc3ccccc3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I23 mock treatment 54600.0 2420.0 0.14 63560.0 -1270.0 -0.1 0.031 0.1826 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 I24 mock treatment 46840.0 -5340.0 -0.31 65480.0 650.0 0.05 -0.1841 -0.5874 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J01 compound treatment 86120.0 33900.0 1.97 58760.0 -6070.0 -0.46 1.0654 0.5277 3086958 TimTec1_007943 CC1CCc2cc(F)cc3c(O)c(C(=O)Nc4ccccn4)c(=O)n1c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J02 compound treatment 57240.0 5060.0 0.29 41840.0 -23000.0 -1.74 -1.0234 -0.5799 1219265 TimTec1_007944 NC(=O)Cc1cc2ccccc2n1Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J03 compound treatment 76680.0 24500.0 1.42 58720.0 -6110.0 -0.46 0.6765 0.4532 1539977 TimTec1_007945 COc1ccc(NC2CS(=O)(=O)CC2NCc3ccco3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J04 compound treatment 62680.0 10500.0 0.61 45760.0 -19100.0 -1.44 -0.5907 -0.3771 1153064 TimTec1_007946 CCC(C(=O)OC)n1cnc2sc(C(=O)Nc3ccccc3)c(C)c2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J05 compound treatment 65200.0 13000.0 0.75 57520.0 -7310.0 -0.55 0.142 0.1518 3212208 TimTec1_007947 COc1ccc(cc1)C(=O)OC2CCN(C)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J06 compound treatment 55640.0 3460.0 0.2 43240.0 -21600.0 -1.63 -1.014 -0.6159 3086959 TimTec1_007948 COC(=O)c1sc(NC(=O)c2ccccc2)c(C#N)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J07 compound treatment 58960.0 6780.0 0.39 56200.0 -8630.0 -0.65 -0.1843 -0.2418 1262960 TimTec1_007949 COc1ccc(OCC(=O)Nc2cccc(NC(=O)c3ccco3)c2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J08 compound treatment 28560.0 -23600.0 -1.37 27240.0 -37600.0 -2.85 -2.9798 -0.9437 3212209 TimTec1_007950 CCc1ccc(cc1)C(=O)Nc2nnn(CC)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J09 compound treatment 18040.0 -34100.0 -1.98 29440.0 -35400.0 -2.68 -3.293 -0.9889 3086960 TimTec1_007951 Cc1cc(N)n2nc(cc2n1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J10 compound treatment 47720.0 -4460.0 -0.26 67120.0 2290.0 0.17 -0.0603 -0.1937 1408804 TimTec1_007952 NC(=O)Cn1cnc2sc3CCCc3c2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J11 compound treatment 13960.0 -38200.0 -2.21 23560.0 -41300.0 -3.12 -3.7749 -0.9858 3086961 TimTec1_007953 COc1ccc(OC2C(N(Cc3ccc4OCOc4c3)C2=O)c5cccs5)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J12 compound treatment 36840.0 -15300.0 -0.89 58840.0 -5990.0 -0.45 -0.9492 -0.9512 3087005 TimTec1_007954 C(Nc1ccccn1)c2cccc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J13 compound treatment 31000.0 -21200.0 -1.23 41840.0 -23000.0 -1.74 -2.0984 -0.9854 1398714 TimTec1_007955 CCOc1ccc(cc1)c2csc(NC(=O)CC)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J14 compound treatment 46480.0 -5700.0 -0.33 58080.0 -6750.0 -0.51 -0.595 -0.9778 3087006 TimTec1_007956 Clc1ccc(CC(=O)NCCCn2ccnc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J15 compound treatment 40640.0 -11500.0 -0.67 63480.0 -1350.0 -0.1 -0.5452 -0.8058 3087007 TimTec1_007957 CC1(CC1)c2ccccc2NC(=O)c3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J16 compound treatment 59040.0 6860.0 0.4 71120.0 6290.0 0.48 0.6176 0.9959 3087008 TimTec1_007958 C(N1CCCCC1)c2cn3ccccc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J17 compound treatment 53960.0 1780.0 0.1 59440.0 -5390.0 -0.41 -0.2157 -0.5127 1535568 TimTec1_007959 COc1ccccc1OCc2nc(no2)c3ccncc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J18 compound treatment 24160.0 -28000.0 -1.62 38440.0 -26400.0 -2.0 -2.5606 -0.9947 1410331 TimTec1_007960 COc1ccc(CCN2CC(=O)C(=C2N)c3nc4ccccc4s3)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J19 compound treatment 74360.0 22200.0 1.28 80320.0 15500.0 1.17 1.7376 0.999 3087009 TimTec1_007961 Cc1ccc(O)c(NC(=O)c2cccs2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J20 compound treatment 72880.0 20700.0 1.2 67920.0 3090.0 0.23 1.0133 0.8294 3087010 TimTec1_007962 Cc1c(sc2ncn(C)c(=O)c12)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J21 compound treatment 41080.0 -11100.0 -0.64 59520.0 -5310.0 -0.4 -0.7391 -0.9744 3212210 TimTec1_007963 Cn1c(NC2CC(=O)N(C2=O)c3ccc(Cl)cc3Cl)cc(=O)n(C)c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J22 compound treatment 58040.0 5860.0 0.34 75560.0 10700.0 0.81 0.8142 0.925 3087011 TimTec1_007964 Cc1c(sc2nc[nH]c(=O)c12)C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J23 mock treatment 40160.0 -12000.0 -0.7 70440.0 5610.0 0.42 -0.1923 -0.2357 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 J24 mock treatment 36640.0 -15500.0 -0.9 57920.0 -6910.0 -0.52 -1.0066 -0.9666 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K01 compound treatment 73720.0 21500.0 1.25 45240.0 -19600.0 -1.48 -0.1662 -0.0858 3212211 TimTec1_007965 CC(=O)Nc1ccccc1c2ccc(C)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K02 compound treatment 71920.0 19700.0 1.14 45160.0 -19700.0 -1.49 -0.2443 -0.1301 1741002 TimTec1_007966 Oc1c(C(=O)Nc2ccc(Cl)cc2Cl)c(=O)n(Cc3ccco3)c4CCCCc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K03 compound treatment 61200.0 9020.0 0.52 42840.0 -22000.0 -1.66 -0.8076 -0.4629 3087012 TimTec1_007967 O=C(Nc1nncs1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K04 compound treatment 47720.0 -4460.0 -0.26 41440.0 -23400.0 -1.77 -1.4348 -0.8019 3212212 TimTec1_007968 CCOc1cc(cc(OCC)c1OCC)c2nc(no2)c3ccc(C)nc3OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K05 compound treatment 4360.0 -47800.0 -2.77 3600.0 -61200.0 -4.63 -5.2365 -0.9698 3087013 TimTec1_007969 CCOC(=O)c1cnc2c(C)c(C)ccc2c1NCCCN(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K06 compound treatment 47240.0 -4940.0 -0.29 41920.0 -22900.0 -1.73 -1.4288 -0.8129 3212213 TimTec1_007970 Clc1ccccc1Cn2c(=O)oc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K07 compound treatment 53240.0 1060.0 0.06 48000.0 -16800.0 -1.27 -0.8575 -0.6724 1136632 TimTec1_007971 Clc1ccc(C(=O)C(C#N)c2nc3ccccc3[nH]2)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K08 compound treatment 45880.0 -6300.0 -0.37 48520.0 -16300.0 -1.23 -1.1312 -0.8786 3212214 TimTec1_007972 O=C(NCCCn1ccnc1)c2cc3ccccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K09 compound treatment 37640.0 -14500.0 -0.84 49320.0 -15500.0 -1.17 -1.426 -0.9868 3212215 TimTec1_007973 CCC(=O)c1cn(CC(=O)N2CCCC2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K10 compound treatment 34240.0 -17900.0 -1.04 50480.0 -14400.0 -1.09 -1.5032 -0.9998 3087014 TimTec1_007974 C=CCc1cccc2cc(C(=O)NCC3CCCO3)c(=O)oc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K11 compound treatment 38640.0 -13500.0 -0.78 48560.0 -16300.0 -1.23 -1.4257 -0.9763 1305056 TimTec1_007975 Clc1cccc(NC(=O)Cn2cnc3ccccc3c2=O)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K12 compound treatment 37400.0 -14800.0 -0.86 50840.0 -14000.0 -1.06 -1.3545 -0.9945 3087015 TimTec1_007976 CC(C)OC(=O)Cn1c(=O)oc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K13 compound treatment 24400.0 -27800.0 -1.61 56600.0 -8230.0 -0.62 -1.5788 -0.9147 3212285 TimTec1_007977 O=C(Cc1ccccc1)N2CCC(CC2)C(=O)NC3CCCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K14 compound treatment 5400.0 -46800.0 -2.71 6240.0 -58600.0 -4.43 -5.0526 -0.9721 3087016 TimTec1_007978 CCc1nn2cc(nc2s1)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K15 compound treatment 45080.0 -7100.0 -0.41 52480.0 -12400.0 -0.93 -0.952 -0.9321 3212286 TimTec1_007979 Clc1ccccc1OCC(=O)N2CCc3ccccc3C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K16 compound treatment 5680.0 -46500.0 -2.69 6200.0 -58600.0 -4.44 -5.0433 -0.9714 1268638 TimTec1_007980 CCCC(=O)Nc1ccc(cc1)c2nc3ccccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K17 compound treatment 47680.0 -4500.0 -0.26 57120.0 -7710.0 -0.58 -0.5972 -0.9341 3212287 TimTec1_007981 OC(=O)c1cccnc1c2nc3ccccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K18 compound treatment 40480.0 -11700.0 -0.68 45920.0 -18900.0 -1.43 -1.4916 -0.9418 1430476 TimTec1_007982 COC(=O)c1cc(sc1NC(=O)C2CCCO2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K19 compound treatment 56320.0 4140.0 0.24 55120.0 -9710.0 -0.73 -0.3503 -0.4531 1234211 TimTec1_007983 CCN(CC)C(=O)COc1cc2oc(=O)cc(CC)c2cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K20 compound treatment 25760.0 -26400.0 -1.53 38120.0 -26700.0 -2.02 -2.5122 -0.9906 3212288 TimTec1_007984 O=C(Cc1ccccc1)Nc2nnc(s2)C3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K21 compound treatment 31880.0 -20300.0 -1.18 52160.0 -12700.0 -0.96 -1.51 -0.9949 3087017 TimTec1_007985 O=C(Nc1ccc2OCCOc2c1)C3(CCOCC3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K22 compound treatment 51200.0 -984.0 -0.06 62760.0 -2070.0 -0.16 -0.1511 -0.9062 3212289 TimTec1_007986 O=C(COC(=O)c1cnccn1)c2ccc3CCCCc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K23 mock treatment 37240.0 -14900.0 -0.87 58920.0 -5910.0 -0.45 -0.9285 -0.9528 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 K24 mock treatment 31960.0 -20200.0 -1.17 49280.0 -15600.0 -1.18 -1.6608 -1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L01 compound treatment 80360.0 28200.0 1.63 54600.0 -10200.0 -0.77 0.6068 0.3358 3212290 TimTec1_007987 Clc1ccc(cc1)N2C(=O)C=C(N3CCOCC3)C2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L02 compound treatment 73520.0 21300.0 1.24 58120.0 -6710.0 -0.51 0.515 0.3853 3087018 TimTec1_007988 C(N1CCC(CC1)N2CCCCC2)c3ccncc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L03 compound treatment 73400.0 21200.0 1.23 56680.0 -8150.0 -0.62 0.433 0.3148 3212291 TimTec1_007989 O=C(NC1CCS(=O)(=O)C1)c2ccc(C#N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L04 compound treatment 64280.0 12100.0 0.7 50360.0 -14500.0 -1.1 -0.2789 -0.2145 1181051 TimTec1_007990 Cc1c(sc2ncn(CC(=O)N)c(=O)c12)C(=O)Nc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L05 compound treatment 61680.0 9500.0 0.55 47160.0 -17700.0 -1.34 -0.5567 -0.3849 3212292 TimTec1_007991 CN1CCC(CC1)OC(=O)Cc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L06 compound treatment 63720.0 11500.0 0.67 50560.0 -14300.0 -1.08 -0.2912 -0.2292 1548607 TimTec1_007992 COC(=O)c1sc(NC(=O)COc2ccc(OC)cc2)c(C#N)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L07 compound treatment 55080.0 2900.0 0.17 54000.0 -10800.0 -0.82 -0.461 -0.5509 1562684 TimTec1_007993 COc1ccccc1CNC(=O)C2COc3ccccc3O2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L08 compound treatment 32000.0 -20200.0 -1.17 40280.0 -24600.0 -1.86 -2.1409 -0.9751 3212293 TimTec1_007994 O=C(Nc1cccc2ncccc12)c3cc4ccccc4o3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L09 compound treatment 42720.0 -9460.0 -0.55 60760.0 -4070.0 -0.31 -0.6056 -0.9628 3087019 TimTec1_007995 Cc1cc2ncc(C(=O)Nc3ccccc3)c(C)n2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L10 compound treatment 42080.0 -10100.0 -0.59 46000.0 -18800.0 -1.43 -1.4218 -0.9227 1358839 TimTec1_007996 O=c1n(Cc2ccccc2)cnc3sc4CCCCc4c13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L11 compound treatment 40200.0 -12000.0 -0.69 54560.0 -10300.0 -0.78 -1.0406 -0.9984 3087020 TimTec1_007997 OC(=O)c1cccc(NCc2ccc3OCOc3c2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L12 compound treatment 36640.0 -15500.0 -0.9 53400.0 -11400.0 -0.87 -1.2486 -0.9998 3212294 TimTec1_007998 CCOc1ccc2nc(Nc3ncc4C(=O)CCCc4n3)nc(C)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L13 compound treatment 1760.0 -50400.0 -2.92 1720.0 -63100.0 -4.78 -5.4437 -0.9722 1728999 TimTec1_007999 CC(Nc1ncnc2ccccc12)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L14 compound treatment 50840.0 -1340.0 -0.08 62640.0 -2190.0 -0.17 -0.1723 -0.9406 3087021 TimTec1_008000 CCCC(C)C(=O)Nc1nnc(C)s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L15 compound treatment 46800.0 -5380.0 -0.31 55360.0 -9470.0 -0.72 -0.7274 -0.9305 3212295 TimTec1_008001 COc1cc(cc(OC)c1OC)C(=O)OC2CSCC2NC(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L16 compound treatment 63640.0 11500.0 0.66 62480.0 -2350.0 -0.18 0.3436 0.5 1295031 TimTec1_008002 Cc1ccc(cc1)c2csc3ncn(CC=C)c(=O)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L17 compound treatment 59200.0 7020.0 0.41 50920.0 -13900.0 -1.05 -0.4571 -0.405 3212296 TimTec1_008003 Nc1nnnn1NCc2ccc(OCC=C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L18 compound treatment 69000.0 16800.0 0.97 61120.0 -3710.0 -0.28 0.4904 0.4836 1488995 TimTec1_008004 CC(NC(=O)c1ccc2[nH]cnc2c1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L19 compound treatment 57920.0 5740.0 0.33 64760.0 -70.0 -0.01 0.2313 0.6957 1871879 TimTec1_008005 CCNc1nnc(s1)c2ccccc2OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L20 compound treatment 48000.0 -4180.0 -0.24 56480.0 -8350.0 -0.63 -0.6183 -0.9134 3212297 TimTec1_008006 COc1ccccc1NC(=O)Cn2cnc3sc(C(=O)OC(C)C)c(C)c3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L21 compound treatment 28560.0 -23600.0 -1.37 34720.0 -30100.0 -2.28 -2.5794 -0.9702 1191843 TimTec1_008007 CC(=O)Nc1cc2nn(nc2cc1C)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L22 compound treatment 30680.0 -21500.0 -1.25 57320.0 -7510.0 -0.57 -1.2829 -0.9368 3212298 TimTec1_008008 NC(=O)Cn1cc(C(=O)c2ccccc2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L23 mock treatment 44000.0 -8180.0 -0.47 60680.0 -4150.0 -0.31 -0.5574 -0.98 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 L24 mock treatment 36840.0 -15300.0 -0.89 65760.0 930.0 0.07 -0.5788 -0.6491 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M01 compound treatment 74480.0 22300.0 1.29 51440.0 -13400.0 -1.01 0.1967 0.1198 3087022 TimTec1_008009 COC(=O)C1C2OC3(CN(C(c4ccccc4)c5ccccc5)C(=O)C13)C=C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M02 compound treatment 6280.0 -45900.0 -2.66 3200.0 -61600.0 -4.67 -5.1793 -0.9645 3212299 TimTec1_008010 CCc1cc2c(NC3CCCC3)ncnc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M03 compound treatment 73440.0 21300.0 1.23 49560.0 -15300.0 -1.16 0.0535 0.0317 3212300 TimTec1_008011 O=C(NCC1CCCO1)C2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M04 compound treatment 57520.0 5340.0 0.31 46600.0 -18200.0 -1.38 -0.7571 -0.5354 3087023 TimTec1_008012 CCOc1nc(C)ccc1c2noc(n2)c3cccc(C)c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M05 compound treatment 65120.0 12900.0 0.75 52760.0 -12100.0 -0.91 -0.1161 -0.0982 3212301 TimTec1_008013 Fc1ccc(cc1)C(=O)OCC(=O)Nc2sc3CCCc3c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M06 compound treatment 63800.0 11600.0 0.67 56760.0 -8070.0 -0.61 0.044 0.0484 3087024 TimTec1_008014 FC(F)(F)Oc1ccc(NC(=O)C2=NCCN2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M07 compound treatment 44240.0 -7940.0 -0.46 54360.0 -10500.0 -0.79 -0.8858 -0.9666 1398079 TimTec1_008015 COc1ccc(NC(=O)C(C)NC(=O)c2ccccc2NC(=O)c3ccco3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M08 compound treatment 22480.0 -29700.0 -1.72 37360.0 -27500.0 -2.08 -2.6872 -0.9956 3212302 TimTec1_008016 CC(C(=O)N1CCCCCC1)(c2ccccc2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M09 compound treatment 34000.0 -18200.0 -1.05 46680.0 -18200.0 -1.37 -1.7164 -0.9914 3087025 TimTec1_008017 CCC(=O)c1cn(CC(=O)N2CCc3ccccc23)c4ccccc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M10 compound treatment 48080.0 -4100.0 -0.24 65920.0 1090.0 0.08 -0.1098 -0.4362 3212303 TimTec1_008018 Clc1ccc2oc(=O)c(cc2c1)C(=O)NCCC3=CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M11 compound treatment 46440.0 -5740.0 -0.33 51360.0 -13500.0 -1.02 -0.9563 -0.8916 3087026 TimTec1_008019 O=S1(=O)N=C(NCc2ccco2)c3ccccc31 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M12 compound treatment 40520.0 -11700.0 -0.68 53760.0 -11100.0 -0.84 -1.0704 -0.9943 3212304 TimTec1_008020 CCc1ccc(NC(=O)CCc2ccc(C)o2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M13 compound treatment 45040.0 -7140.0 -0.41 62560.0 -2270.0 -0.17 -0.4142 -0.9242 3087027 TimTec1_008021 CN1CCN(CC1)C(=O)CNS(=O)(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M14 compound treatment 60920.0 8740.0 0.51 63280.0 -1550.0 -0.12 0.2749 0.5292 3212305 TimTec1_008022 Cc1nc2ccc(cc2nc1C)C(=O)OCC(=O)c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M15 compound treatment 64520.0 12300.0 0.71 56120.0 -8710.0 -0.66 0.0392 0.0403 3087028 TimTec1_008023 Fc1ccc(cc1)C(=O)COC(=O)Cc2c[nH]c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M16 compound treatment 65280.0 13100.0 0.76 56280.0 -8550.0 -0.65 0.0789 0.0791 1683207 TimTec1_008024 COc1ccc(cc1OC)n2cnc3ccccc3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M17 compound treatment 60560.0 8380.0 0.49 53800.0 -11000.0 -0.83 -0.2472 -0.256 1652913 TimTec1_008025 CN(C(=O)CCc1nc2ccccc2s1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M18 compound treatment 64240.0 12100.0 0.7 60240.0 -4590.0 -0.35 0.2482 0.3182 1732533 TimTec1_008026 CCOC(=O)c1cnc2ccccc2c1NCCO 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M19 compound treatment 46640.0 -5540.0 -0.32 44280.0 -20600.0 -1.56 -1.327 -0.8355 1566325 TimTec1_008027 CCOC(=O)C1CCN(CC1)c2ncnc3n(ncc23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M20 compound treatment 57680.0 5500.0 0.32 73560.0 8730.0 0.66 0.6924 0.944 3087029 TimTec1_008028 Oc1c2CN(Cc3ccccc3)CCc2nc4nnnn14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M21 compound treatment 18640.0 -33500.0 -1.94 59800.0 -5030.0 -0.38 -1.6435 -0.8299 3212306 TimTec1_008029 Cc1ccc(NC(=O)CC2COc3ccccc3O2)cc1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M22 compound treatment 13640.0 -38500.0 -2.23 15840.0 -49000.0 -3.71 -4.2012 -0.9705 3087030 TimTec1_008030 CCC(=O)Nc1ccc2nc([nH]c2c1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M23 mock treatment 38560.0 -13600.0 -0.79 63920.0 -910.0 -0.07 -0.6068 -0.7659 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 M24 mock treatment 43040.0 -9140.0 -0.53 58000.0 -6830.0 -0.52 -0.7402 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N01 compound treatment 59920.0 7740.0 0.45 38440.0 -26400.0 -2.0 -1.0956 -0.5351 1344636 TimTec1_008031 Cc1ccc2n3CCN(C4CCO4)C5CCCc(c53)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N02 compound treatment 60320.0 8140.0 0.47 50840.0 -14000.0 -1.06 -0.4155 -0.3584 1223236 TimTec1_008032 CCCC(=O)c1cn(CC(=O)OC)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N03 compound treatment 55680.0 3500.0 0.2 36920.0 -27900.0 -2.11 -1.3506 -0.6364 3212369 TimTec1_008033 O=c1sc2ccccc2n1Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N04 compound treatment 49480.0 -2700.0 -0.16 44600.0 -20200.0 -1.53 -1.1936 -0.7754 1413258 TimTec1_008034 CC1CCN(CC1)C(=O)Cn2cnc3sc(C(=O)Nc4ccccc4)c(C)c3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N05 compound treatment 54400.0 2220.0 0.13 52280.0 -12600.0 -0.95 -0.5809 -0.606 3087031 TimTec1_008035 O=C(Cc1ccccc1)OCCN2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N06 compound treatment 52600.0 416.0 0.02 53000.0 -11800.0 -0.9 -0.6161 -0.6878 1462249 TimTec1_008036 O=c1[nH]c2ccc(Oc3ccc4[nH]c(=O)c(=O)[nH]c4c3)cc2[nH]c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N07 compound treatment 32560.0 -19600.0 -1.14 50400.0 -14400.0 -1.09 -1.5763 -0.9998 1786652 TimTec1_008037 O=C(C1COc2ccccc2O1)N3CCc4ccccc4C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N08 compound treatment 34720.0 -17500.0 -1.01 47800.0 -17000.0 -1.29 -1.627 -0.9928 3087059 TimTec1_008038 COC(=O)c1cc2nc(cc(n2n1)C(F)(F)F)c3ccc(F)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N09 compound treatment 38080.0 -14100.0 -0.82 51280.0 -13600.0 -1.03 -1.3031 -0.9937 3087060 TimTec1_008039 CCc1cc(=O)n2nc(C)c(c3ccccc3OC)c2[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N10 compound treatment 39480.0 -12700.0 -0.74 48440.0 -16400.0 -1.24 -1.3977 -0.9689 3087061 TimTec1_008040 CCOC(=O)c1sc2ncn(CC(=O)OC)c(=O)c2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N11 compound treatment 36400.0 -15800.0 -0.91 48600.0 -16200.0 -1.23 -1.5153 -0.9894 3087062 TimTec1_008041 CCCn1nnnc1NCc2ccc(cc2)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N12 compound treatment 44640.0 -7540.0 -0.44 68120.0 3290.0 0.25 -0.133 -0.2643 3087063 TimTec1_008042 Cn1ncc2c(Nc3ccccc3)ncnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N13 compound treatment 38640.0 -13500.0 -0.78 47560.0 -17300.0 -1.31 -1.4792 -0.9702 3087064 TimTec1_008043 Clc1ccc(OCCCC(=O)N2CCCCCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N14 compound treatment 58720.0 6540.0 0.38 65080.0 250.0 0.02 0.2812 0.7415 3087065 TimTec1_008044 Fc1cccc(c1)C(=O)Nc2ncccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N15 compound treatment 54440.0 2260.0 0.13 55680.0 -9150.0 -0.69 -0.3973 -0.5637 3087066 TimTec1_008045 Cc1ccc(cc1)C2CC(=C3C(Nc4ccccc4N=C3C2)c5cccnc5)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N16 compound treatment 55520.0 3340.0 0.19 53760.0 -11100.0 -0.84 -0.4558 -0.5301 1678072 TimTec1_008046 COC(=O)C(C)n1cnc2scc(c3ccc(OC)cc3)c2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N17 compound treatment 72520.0 20300.0 1.18 62480.0 -2350.0 -0.18 0.7074 0.5936 3087067 TimTec1_008047 OC(=O)CCCC(=O)Nc1cccc(NC(=O)c2ccco2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N18 compound treatment 60320.0 8140.0 0.47 62560.0 -2270.0 -0.17 0.2118 0.4222 1723066 TimTec1_008048 CCCOC(=O)Nc1sc2CCCc2c1C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N19 compound treatment 45280.0 -6900.0 -0.4 51520.0 -13300.0 -1.01 -0.9952 -0.9181 3212370 TimTec1_008049 CC1=C(C(C2=C(CCCC2=O)N1)c3ccc(cc3)C(F)(F)F)C(=O)N4CCOCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N20 compound treatment 27240.0 -24900.0 -1.45 30680.0 -34200.0 -2.58 -2.8497 -0.9623 3087068 TimTec1_008050 O=C(Nc1ccc(cc1)N2CCOCC2)c3nc4ccccc4s3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N21 compound treatment 47040.0 -5140.0 -0.3 63840.0 -990.0 -0.07 -0.2637 -0.8582 3087069 TimTec1_008051 Brc1ccc(COC(=O)c2cccnc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N22 compound treatment 56160.0 3980.0 0.23 65280.0 450.0 0.03 0.187 0.8029 3212371 TimTec1_008052 COc1cc2c(C(=O)O)c(C)n(C)c2cc1Br 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N23 mock treatment 43400.0 -8780.0 -0.51 30040.0 -34800.0 -2.63 -2.222 -0.8284 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 N24 mock treatment 43040.0 -9140.0 -0.53 65280.0 450.0 0.03 -0.3505 -0.6603 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O01 compound treatment 84120.0 31900.0 1.85 53960.0 -10900.0 -0.82 0.7266 0.3588 3212372 TimTec1_008053 CCOC(=O)C1C2OC3(CN(Cc4ccc(C)cc4)C(=O)C13)C=C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O02 compound treatment 83360.0 31200.0 1.81 60000.0 -4830.0 -0.37 1.0187 0.5528 1226227 TimTec1_008054 COc1ccccc1OCCN2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O03 compound treatment 49280.0 -2900.0 -0.17 38000.0 -26800.0 -2.03 -1.555 -0.7631 1257135 TimTec1_008055 CC(C)(C)C(=O)Nc1cccc(c1)c2nc3ccccc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O04 compound treatment 59640.0 7460.0 0.43 46760.0 -18100.0 -1.37 -0.6617 -0.4613 3087070 TimTec1_008056 COCC(=O)N(Cc1cc2cccc(C)c2nc1O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O05 compound treatment 56880.0 4700.0 0.27 53000.0 -11800.0 -0.9 -0.4408 -0.471 1217386 TimTec1_008057 COc1ccccc1c2coc3c(CN(C)C4CCCCC4)c(O)ccc3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O06 compound treatment 47600.0 -4580.0 -0.27 55440.0 -9390.0 -0.71 -0.6904 -0.9099 1319384 TimTec1_008058 C=CCn1c(CNC(=O)c2ccccc2)nc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O07 compound treatment 8720.0 -43500.0 -2.52 12520.0 -52300.0 -3.96 -4.5805 -0.9761 1357487 TimTec1_008059 Cc1ccc(cc1)c2csc3ncnc(NCCO)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O08 compound treatment 45000.0 -7180.0 -0.42 62480.0 -2350.0 -0.18 -0.4201 -0.9281 3087071 TimTec1_008060 Cc1sc(c(C(=O)O)c1C)n2cccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O09 compound treatment 22600.0 -29600.0 -1.71 31680.0 -33200.0 -2.51 -2.9863 -0.9827 3212373 TimTec1_008061 CCC(=O)c1cn(Cc2ccccc2C#N)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O10 compound treatment 44040.0 -8140.0 -0.47 53320.0 -11500.0 -0.87 -0.9497 -0.9585 3087072 TimTec1_008062 COc1ccc2oc(=O)c(cc2c1)C(=O)NC3CCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O11 compound treatment 47080.0 -5100.0 -0.3 68960.0 4130.0 0.31 0.012 0.0278 3212374 TimTec1_008063 CCc1ccccc1NC(=O)Cn2cnc3ccccc3c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O12 compound treatment 56560.0 4380.0 0.25 65840.0 1010.0 0.08 0.2333 0.8811 3087073 TimTec1_008064 COC(=O)Cn1c(=O)sc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O13 compound treatment 46480.0 -5700.0 -0.33 64240.0 -590.0 -0.04 -0.2653 -0.7954 3212375 TimTec1_008065 Cc1nc2ccccc2c(=O)n1c3ccc(Cl)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O14 compound treatment 66800.0 14600.0 0.85 66120.0 1290.0 0.1 0.6678 0.7835 3087074 TimTec1_008066 O=C(COC(=O)c1ccncc1)c2ccc3ccccc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O15 compound treatment 64560.0 12400.0 0.72 64040.0 -790.0 -0.06 0.4647 0.6459 3212376 TimTec1_008067 CN(C)c1ncnc2sc(C)c(C)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O16 compound treatment 74960.0 22800.0 1.32 76520.0 11700.0 0.88 1.5588 0.9811 1595494 TimTec1_008068 C(C1COc2ccccc2N1)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O17 compound treatment 45360.0 -6820.0 -0.4 41880.0 -23000.0 -1.74 -1.5079 -0.8464 1719142 TimTec1_008069 CC1(C)C2(C)CCC1(CC2=O)C(=O)Nc3ccc(Cl)cn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O18 compound treatment 70680.0 18500.0 1.07 75160.0 10300.0 0.78 1.3107 0.988 3212377 TimTec1_008070 Cc1cc(Cl)ccc1NC(=O)COC(=O)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O19 compound treatment 62560.0 10400.0 0.6 70960.0 6130.0 0.46 0.7532 0.9918 3212378 TimTec1_008071 COc1ccc(cc1)C2(CCCC2)C(=O)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O20 compound treatment 51800.0 -384.0 -0.02 74480.0 9650.0 0.73 0.5008 0.6853 3087075 TimTec1_008072 C(N1CCCCCC1)c2nc3ccccc3[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O21 compound treatment 50560.0 -1620.0 -0.09 62680.0 -2150.0 -0.16 -0.1816 -0.9661 3212379 TimTec1_008073 CCOC(=O)N1CCC2(CC1)C(=C(N)OC3=C2C(=O)CCC3)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O22 compound treatment 45600.0 -6580.0 -0.38 67840.0 3010.0 0.23 -0.1086 -0.2445 3087076 TimTec1_008074 CC(C)c1nc2cc(NC(=O)C3CCCCC3)ccc2[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O23 mock treatment 47960.0 -4220.0 -0.24 57960.0 -6870.0 -0.52 -0.5407 -0.9409 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 O24 mock treatment 43680.0 -8500.0 -0.49 52360.0 -12500.0 -0.94 -1.0158 -0.954 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P01 compound treatment 72840.0 20700.0 1.2 49920.0 -14900.0 -1.13 0.0482 0.0293 3212380 TimTec1_008075 CCOCC(=O)N1CCc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P02 compound treatment 57800.0 5620.0 0.33 35440.0 -29400.0 -2.22 -1.343 -0.5973 3212381 TimTec1_008076 NC1=C(C#N)C2(CCN(Cc3ccccc3)CC2)C(=C4Nc5ccccc5N41)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P03 compound treatment 59080.0 6900.0 0.4 48120.0 -16700.0 -1.26 -0.6119 -0.4613 1118497 TimTec1_008077 OC1CS(=O)(=O)CC1Nc2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P04 compound treatment 55680.0 3500.0 0.2 47920.0 -16900.0 -1.28 -0.7619 -0.5879 1599062 TimTec1_008078 O=C(Cn1cnc2scc(c3ccccc3)c2c1=O)N4CCCCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P05 compound treatment 58040.0 5860.0 0.34 53040.0 -11800.0 -0.89 -0.3911 -0.4097 3087077 TimTec1_008079 CC1CCN(CC1)C(=O)c2cc3ccccc3o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P06 compound treatment 35840.0 -16300.0 -0.95 44760.0 -20100.0 -1.52 -1.7438 -0.9741 3212382 TimTec1_008080 CCCOC(=O)c1ccc(cc1)n2nc(c3c(C)cc(=O)oc23)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P07 compound treatment 29320.0 -22900.0 -1.32 43920.0 -20900.0 -1.58 -2.0559 -0.9961 3087078 TimTec1_008081 CCc1ccc(CN2CCC(CC2)N3CCCCC3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P08 compound treatment 47720.0 -4460.0 -0.26 64000.0 -830.0 -0.06 -0.2273 -0.854 3212383 TimTec1_008082 CCCNC(=O)c1cnn2c(C)cc(C)nc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P09 compound treatment 42040.0 -10100.0 -0.59 56760.0 -8070.0 -0.61 -0.8475 -0.9998 1549606 TimTec1_008083 Clc1ccc2oc(=O)n(CN3CCCCC3)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P10 compound treatment 37720.0 -14500.0 -0.84 52520.0 -12300.0 -0.93 -1.2514 -0.9986 3212384 TimTec1_008084 CCn1cnc2scc(c3ccccc3)c2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P11 compound treatment 49320.0 -2860.0 -0.17 67960.0 3130.0 0.24 0.0502 0.1736 3087079 TimTec1_008085 COc1cc(CNCc2cccnc2)ccc1OCC(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P12 compound treatment 40800.0 -11400.0 -0.66 60800.0 -4030.0 -0.31 -0.6821 -0.9386 3212385 TimTec1_008086 CC(Oc1ccc2c(C)cc(=O)oc2c1)C(=O)NC3CCCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P13 compound treatment 53760.0 1580.0 0.09 56480.0 -8350.0 -0.63 -0.3823 -0.5987 3212386 TimTec1_008087 Cc1sc2ncn(CC(=O)OC3CCCCC3)c(=O)c2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P14 compound treatment 64720.0 12500.0 0.73 66040.0 1210.0 0.09 0.5784 0.79 3087080 TimTec1_008088 Cc1ccc(CC(=O)N2CCOCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P15 compound treatment 68720.0 16500.0 0.96 57560.0 -7270.0 -0.55 0.2883 0.261 3212387 TimTec1_008089 COC(=O)C1C(C)CC2=C(C(Nc3ccccc3N2)c4ccccc4C)C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P16 compound treatment 63360.0 11200.0 0.65 57880.0 -6950.0 -0.53 0.0859 0.1029 1622942 TimTec1_008090 CCCn1cnc2scc(c3ccc(OC)cc3)c2c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P17 compound treatment 3160.0 -49000.0 -2.84 2480.0 -62400.0 -4.72 -5.3456 -0.9705 3212388 TimTec1_008091 O=C(Nc1ccc(cc1)c2nc3ccccc3s2)C4CCCO4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P18 compound treatment 45520.0 -6660.0 -0.39 59680.0 -5150.0 -0.39 -0.5486 -1.0 3087081 TimTec1_008092 NC1=C(C(=O)CN1c2ccccc2)c3nc4ccccc4c(=O)[nH]3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P19 compound treatment 28360.0 -23800.0 -1.38 34160.0 -30700.0 -2.32 -2.6176 -0.9692 3212389 TimTec1_008093 CCOc1cccc(c1)C2C(=CN(CC)C=C2C(=O)OC)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P20 compound treatment 52400.0 216.0 0.01 66800.0 1970.0 0.15 0.1143 0.7638 3087082 TimTec1_008094 Cc1nc2ccc(NC(=O)N3CCSCC3)cc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P21 compound treatment 35040.0 -17100.0 -0.99 37480.0 -27400.0 -2.07 -2.1662 -0.9434 3212390 TimTec1_008095 CC(C)OC(=O)c1ccc(COC(=O)CNC(=O)c2ccco2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P22 compound treatment 25320.0 -26900.0 -1.56 40120.0 -24700.0 -1.87 -2.4231 -0.9958 3087083 TimTec1_008096 Fc1cccc(CNCC2CCCO2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P23 mock treatment 39160.0 -13000.0 -0.75 68800.0 3970.0 0.3 -0.3211 -0.3953 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2085 P24 mock treatment 50760.0 -1420.0 -0.08 71800.0 6970.0 0.53 0.3147 0.5894 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A01 compound treatment 38920.0 -8500.0 -0.49 56960.0 9960.0 0.75 0.1849 0.2053 3212391 TimTec1_008097 Cc1ccsc1CNCC2CCCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A02 compound treatment 44080.0 -3340.0 -0.19 51920.0 4920.0 0.37 0.1265 0.3015 3212454 TimTec1_008098 Clc1cccc(CN2CCC(CC2)C(=O)N(CC=C)CC=C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A03 compound treatment 45880.0 -1540.0 -0.09 49840.0 2840.0 0.21 0.0889 0.3821 3087084 TimTec1_008099 NC(=O)c1c(NC(=O)c2cc(on2)c3ccccc3)sc4CCCCc14 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A04 compound treatment 48480.0 1060.0 0.06 49160.0 2160.0 0.16 0.159 0.9108 3212455 TimTec1_008100 Oc1ccccc1CNCC2CCCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A05 compound treatment 46840.0 -579.0 -0.03 51280.0 4280.0 0.32 0.2053 0.6305 3212456 TimTec1_008101 CNCC(O)Cn1c(nc2ccccc12)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A06 compound treatment 43520.0 -3900.0 -0.23 47600.0 599.0 0.05 -0.1277 -0.5542 3212457 TimTec1_008102 O=C(NCCc1ccccc1)C2CCN(CC2)C(=O)C(C(=O)c3ccccc3)n4ccccc4=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A07 compound treatment 27920.0 -19500.0 -1.13 35520.0 -11500.0 -0.87 -1.4133 -0.9916 1688145 TimTec1_008103 CC(=O)Nc1cccc(c1)c2cn3ccccc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A08 compound treatment 44800.0 -2620.0 -0.15 45560.0 -1440.0 -0.11 -0.1844 -0.9869 3087085 TimTec1_008104 Cc1c(sc2nc[nH]c(=O)c12)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A09 compound treatment 41680.0 -5740.0 -0.33 43720.0 -3280.0 -0.25 -0.4107 -0.9897 1173874 TimTec1_008105 CCN1C(=O)C(C(=O)O)C(=O)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A10 compound treatment 33080.0 -14300.0 -0.83 32880.0 -14100.0 -1.07 -1.3433 -0.9922 3087086 TimTec1_008106 CC(NCC1OCc2ccccc2CO1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A11 compound treatment 37080.0 -10300.0 -0.6 33200.0 -13800.0 -1.04 -1.1623 -0.9652 3212458 TimTec1_008107 CCCC1CCC(CC1)C2CCC(CC2)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A12 compound treatment 28280.0 -19100.0 -1.11 32040.0 -15000.0 -1.13 -1.5849 -0.9999 1532351 TimTec1_008108 CC(C)(C)Oc1ccc(cc1)C(=O)N(Cc2ccc(F)cc2)C3CCOC(C)(C)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A13 compound treatment 40480.0 -6940.0 -0.4 43080.0 -3920.0 -0.3 -0.4941 -0.9889 1359062 TimTec1_008109 CCOc1ccc2ncc(C(=O)O)c(O)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A14 compound treatment 23000.0 -24400.0 -1.41 30120.0 -16900.0 -1.28 -1.9039 -0.9987 3212459 TimTec1_008110 CN(C)c1ccc(CNCCC2(CCOC(C)(C)C2)c3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A15 compound treatment 41400.0 -6020.0 -0.35 41800.0 -5200.0 -0.39 -0.525 -0.9982 1788332 TimTec1_008111 CCOc1ccc(NC(=O)C2C(C3OC2C=C3)C(=O)O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A16 compound treatment 36760.0 -10700.0 -0.62 45560.0 -1440.0 -0.11 -0.5138 -0.8193 3212460 TimTec1_008112 CC1(C)CC(CC(C)(C)N1)NCc2ccccc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A17 compound treatment 35600.0 -11800.0 -0.68 48120.0 1120.0 0.08 -0.4243 -0.615 3087087 TimTec1_008113 COc1ccccc1C2=NOC(C2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A18 compound treatment 37040.0 -10400.0 -0.6 47880.0 879.0 0.07 -0.3782 -0.6251 1394442 TimTec1_008114 Fc1ccc(CNCc2cccnc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A19 compound treatment 24520.0 -22900.0 -1.33 35400.0 -11600.0 -0.88 -1.5591 -0.9799 3212461 TimTec1_008115 Cc1ccc(Nc2nc(cs2)C(=O)N3CCCCC3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A20 compound treatment 49000.0 1580.0 0.09 53120.0 6120.0 0.46 0.3923 0.8309 3087088 TimTec1_008116 COc1ccc(CNCCN(C)C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A21 compound treatment 45840.0 -1580.0 -0.09 49640.0 2640.0 0.2 0.0766 0.3485 3087089 TimTec1_008117 CN1CCN(Cc2cn[nH]c2c3ccccc3)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A22 compound treatment 48960.0 1540.0 0.09 49680.0 2680.0 0.2 0.2065 0.9321 3212462 TimTec1_008118 C(CN1CCOCC1)NCc2ccncc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A23 mock treatment 47360.0 -58.8 0.0 55200.0 8200.0 0.62 0.4364 0.7032 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 A24 mock treatment 58400.0 11000.0 0.64 58080.0 11100.0 0.84 1.0429 0.9907 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B01 compound treatment 39120.0 -8300.0 -0.48 52520.0 5520.0 0.42 -0.0446 -0.07 1348556 TimTec1_008119 OC(=O)CNC(=O)COc1ccc(cc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B02 compound treatment 53400.0 5980.0 0.35 52560.0 5560.0 0.42 0.5426 0.9954 3087090 TimTec1_008120 N#CNC1=NCN(CCN2CCOCC2)CN1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B03 compound treatment 49880.0 2460.0 0.14 56000.0 9000.0 0.68 0.5825 0.837 1514480 TimTec1_008121 OC(=O)CCCC(=O)Nc1ccccc1N2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B04 compound treatment 50600.0 3180.0 0.18 48080.0 1080.0 0.08 0.1881 0.9329 3087137 TimTec1_008122 COc1cccc(c1)C(=O)N2CCC(CC2)C(=O)N3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B05 compound treatment 54920.0 7500.0 0.43 39880.0 -7120.0 -0.54 -0.0738 -0.1066 3087138 TimTec1_008123 CC1CCCCN1C(C(=O)O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B06 compound treatment 45720.0 -1700.0 -0.1 41440.0 -5560.0 -0.42 -0.3673 -0.8495 3087139 TimTec1_008124 NC(=O)C1CCCN(C1)S(=O)(=O)c2ccc(Cl)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B07 compound treatment 43040.0 -4380.0 -0.25 40000.0 -7000.0 -0.53 -0.5541 -0.9431 1468759 TimTec1_008125 CC1(C)CC(CCN)(Cc2ccccc2)CCO1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B08 compound treatment 30920.0 -16500.0 -0.96 41200.0 -5800.0 -0.44 -0.9864 -0.9377 3087140 TimTec1_008126 NC1=C(C#N)C(c2ccsc2)c3oc(CO)cc(=O)c3O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B09 compound treatment 31360.0 -16100.0 -0.93 43680.0 -3320.0 -0.25 -0.8357 -0.8671 1583111 TimTec1_008127 Cc1cccc(Oc2ccc(NC(=O)CCCC(=O)O)cc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B10 compound treatment 33000.0 -14400.0 -0.84 41280.0 -5720.0 -0.43 -0.8969 -0.9532 3087141 TimTec1_008128 CCCC1C(=C(N)OC2=C1C(=O)CCC2)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B11 compound treatment 21680.0 -25700.0 -1.49 26160.0 -20800.0 -1.58 -2.17 -0.9996 1405409 TimTec1_008129 CCOC(=O)c1cn(C2CC2)c3c(F)c(F)c(F)cc3c1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B12 compound treatment 35800.0 -11600.0 -0.67 38520.0 -8480.0 -0.64 -0.9299 -0.9997 3212463 TimTec1_008130 CC(CCc1ccccc1)NCc2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B13 compound treatment 35800.0 -11600.0 -0.67 45760.0 -1240.0 -0.09 -0.5424 -0.7981 1179105 TimTec1_008131 OC(=O)C(CC(=O)Nc1ccccc1)C2CCCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B14 compound treatment 43600.0 -3820.0 -0.22 43720.0 -3280.0 -0.25 -0.3321 -0.9983 3087142 TimTec1_008132 O=C(COc1ccccc1)NCCN2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B15 compound treatment 40440.0 -6980.0 -0.4 44760.0 -2240.0 -0.17 -0.4059 -0.9256 3212464 TimTec1_008133 CC(Cc1ccccc1)NC(=O)c2cnc[nH]2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B16 compound treatment 37080.0 -10300.0 -0.6 51200.0 4200.0 0.32 -0.1988 -0.2932 3087143 TimTec1_008134 OC(=O)COCC(=O)Nc1ccc(Br)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B17 compound treatment 40040.0 -7380.0 -0.43 42480.0 -4520.0 -0.34 -0.5443 -0.9939 3212465 TimTec1_008135 CN(C)CC#CCN1CCCC2(CCOC(C)(C)C2)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B18 compound treatment 42680.0 -4740.0 -0.27 51040.0 4040.0 0.31 0.022 0.0536 3087144 TimTec1_008136 Sc1nnc(CN2CCOCC2)n1c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B19 compound treatment 38800.0 -8620.0 -0.5 46040.0 -961.0 -0.07 -0.4045 -0.8017 1605075 TimTec1_008137 CCCC(=O)c1cc(F)c(cc1C)N2CCN(C)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B20 compound treatment 42960.0 -4460.0 -0.26 48320.0 1320.0 0.1 -0.1121 -0.4047 3087145 TimTec1_008138 Cc1ccc(NC(=O)c2ccco2)c(N)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B21 compound treatment 53160.0 5740.0 0.33 47520.0 519.0 0.04 0.263 0.7851 3212466 TimTec1_008139 CC(C)(C)NC(=O)c1cc(NC(=O)C(F)(F)F)cc(NC(=O)C(F)(F)F)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B22 compound treatment 55960.0 8540.0 0.49 53400.0 6400.0 0.48 0.6924 0.9999 1098688 TimTec1_008140 CCN(CC)Cc1c(C)nc2ccccc2c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B23 mock treatment 49160.0 1740.0 0.1 55080.0 8080.0 0.61 0.5037 0.8128 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 B24 mock treatment 44800.0 -2620.0 -0.15 54680.0 7680.0 0.58 0.3037 0.5056 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C01 compound treatment 33800.0 -13600.0 -0.79 45800.0 -1200.0 -0.09 -0.6222 -0.7834 3212467 TimTec1_008141 OC(=O)c1cccc(NCc2ccncc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C02 compound treatment 38640.0 -8780.0 -0.51 47760.0 759.0 0.06 -0.319 -0.6233 3212468 TimTec1_008142 COc1cc(CN2CCC(CC2)C(=O)N3CCN(CC3)c4ccccc4F)cc(OC)c1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C03 compound treatment 36240.0 -11200.0 -0.65 36360.0 -10600.0 -0.81 -1.0275 -0.9942 3087146 TimTec1_008143 CN(C1CCCCC1)C(=O)c2cc(on2)c3ccc(C)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C04 compound treatment 48920.0 1500.0 0.09 43360.0 -3640.0 -0.28 -0.1334 -0.4615 3212469 TimTec1_008144 CCOC(=O)C1CCN(Cc2cccc(OC)c2O)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C05 compound treatment 46480.0 -939.0 -0.05 42240.0 -4760.0 -0.36 -0.2933 -0.8047 1633390 TimTec1_008145 OC(=O)C1CCCN1S(=O)(=O)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C06 compound treatment 8160.0 -39300.0 -2.27 11760.0 -35200.0 -2.67 -3.4946 -0.9969 3212470 TimTec1_008146 CN(Cc1ccccc1)C(=O)c2csc(Nc3ccc(C)cc3)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C07 compound treatment 27080.0 -20300.0 -1.18 40520.0 -6480.0 -0.49 -1.1801 -0.9246 3087147 TimTec1_008147 CCNC(=O)c1sc(nc1C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C08 compound treatment 25840.0 -21600.0 -1.25 41880.0 -5120.0 -0.39 -1.1582 -0.8848 1420669 TimTec1_008148 OC(=O)C1Nc2ccccc2C3C=CCC31 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C09 compound treatment 26440.0 -21000.0 -1.22 31560.0 -15400.0 -1.17 -1.6859 -0.9998 3087148 TimTec1_008149 Cc1ccc(cc1)C(=O)C2CCOC(C)(C)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C10 compound treatment 30520.0 -16900.0 -0.98 27520.0 -19500.0 -1.47 -1.735 -0.9802 1919750 TimTec1_008150 CC1=CCC(Cc2nc3ccccc3o2)C1(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C11 compound treatment 42880.0 -4540.0 -0.26 48520.0 1520.0 0.11 -0.1047 -0.3647 1520076 TimTec1_008151 CCc1nc2ccccc2c(N)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C12 compound treatment 23560.0 -23900.0 -1.38 26480.0 -20500.0 -1.55 -2.0758 -0.9983 1690846 TimTec1_008152 CC(=O)N(CCC(Cc1ccccc1)c2ccc3OCOc3c2)Cc4ccc5OCOc5c4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C13 compound treatment 25240.0 -22200.0 -1.28 23520.0 -23500.0 -1.78 -2.1654 -0.9873 1538543 TimTec1_008153 COC(=O)c1cc2ccccc2c(c1O)c3c(O)ccc4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C14 compound treatment 27000.0 -20400.0 -1.18 35840.0 -11200.0 -0.84 -1.4339 -0.9864 1456541 TimTec1_008154 COc1ccc(cc1)C(=O)N2CC(C)OC(C)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C15 compound treatment 38440.0 -8980.0 -0.52 44400.0 -2600.0 -0.2 -0.5071 -0.9116 1530194 TimTec1_008155 Cc1c(C)c2cc(ccc2n1Cc3ccccc3)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C16 compound treatment 29080.0 -18300.0 -1.06 24640.0 -22400.0 -1.69 -1.9482 -0.9748 3212471 TimTec1_008156 CC1CCN(CC1)c2c(N)cccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C17 compound treatment 38560.0 -8860.0 -0.51 39320.0 -7680.0 -0.58 -0.7741 -0.9981 3087149 TimTec1_008157 OC(=O)C1CC(=NO1)c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C18 compound treatment 38400.0 -9020.0 -0.52 42040.0 -4960.0 -0.38 -0.635 -0.9869 1649056 TimTec1_008158 Cc1ccccc1CNCc2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C19 compound treatment 12800.0 -34600.0 -2.01 18240.0 -28800.0 -2.18 -2.9577 -0.9992 3212472 TimTec1_008159 COc1ccc(Nc2nc(cs2)C(=O)NCc3ccccc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C20 compound treatment 31240.0 -16200.0 -0.94 38640.0 -8360.0 -0.63 -1.1103 -0.9817 3087150 TimTec1_008160 Cc1ccc(CNCc2ccncc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C21 compound treatment 45240.0 -2180.0 -0.13 48640.0 1640.0 0.12 -0.0015 -0.0087 3212473 TimTec1_008161 CCN(CCO)Cc1cn[nH]c1c2ccc(C)c(C)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C22 compound treatment 52720.0 5300.0 0.31 52960.0 5960.0 0.45 0.5361 0.9825 3087151 TimTec1_008162 Cc1ccc(CNCc2ccccc2)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C23 mock treatment 53560.0 6140.0 0.36 51760.0 4760.0 0.36 0.5063 1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 C24 mock treatment 61120.0 13700.0 0.79 52240.0 5240.0 0.4 0.8417 0.9486 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D01 compound treatment 32520.0 -14900.0 -0.86 50640.0 3640.0 0.28 -0.4156 -0.4587 1735820 TimTec1_008163 Cc1c(C#N)c2ccccc2n1CC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D02 compound treatment 47800.0 381.0 0.02 48280.0 1280.0 0.1 0.0841 0.8467 3212773 TimTec1_008164 Oc1ccc2ccccc2c1CNn3cnnc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D03 compound treatment 54200.0 6780.0 0.39 46360.0 -641.0 -0.05 0.2435 0.6151 1670020 TimTec1_008165 OC(=O)CCC(=O)N1CC(=O)Nc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D04 compound treatment 40920.0 -6500.0 -0.38 40600.0 -6400.0 -0.48 -0.6089 -0.9922 3087152 TimTec1_008166 Cc1ccc(cc1Cl)n2c(C)cc(C)c(C#N)c2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D05 compound treatment 50680.0 3260.0 0.19 46720.0 -281.0 -0.02 0.1186 0.6235 3212774 TimTec1_008167 CC(C)c1nc2ccccc2n1C(C)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D06 compound treatment 27760.0 -19700.0 -1.14 35840.0 -11200.0 -0.84 -1.4028 -0.9892 3212775 TimTec1_008168 COc1cc2[nH]c(=O)c(C(=O)NCCCc3ccccc3)c(O)c2cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D07 compound treatment 16720.0 -30700.0 -1.78 27040.0 -20000.0 -1.51 -2.3261 -0.9967 1444599 TimTec1_008169 NCCC(Cc1ccccc1)c2ccc3OCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D08 compound treatment 30080.0 -17300.0 -1.0 43760.0 -3240.0 -0.25 -0.8838 -0.8547 3212776 TimTec1_008170 NC(=O)COc1ccc(cc1Cl)C2C3=C(CCCC3=O)OC4=C2C(=O)CCC4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D09 compound treatment 34920.0 -12500.0 -0.72 40520.0 -6480.0 -0.49 -0.859 -0.982 3087153 TimTec1_008171 Clc1c(sc2ccccc12)C(=O)OCCN3CCOCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D10 compound treatment 25320.0 -22100.0 -1.28 29960.0 -17000.0 -1.29 -1.8175 -1.0 1395566 TimTec1_008172 Oc1cc(=O)[nH]c2nc(Nc3ccccc3)sc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D11 compound treatment 44240.0 -3180.0 -0.18 41120.0 -5880.0 -0.45 -0.445 -0.9237 1499067 TimTec1_008173 CC1(C)CC(=O)C=C(C1)NCc2ccc(cc2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D12 compound treatment 37400.0 -10000.0 -0.58 39440.0 -7560.0 -0.57 -0.8152 -1.0 3087154 TimTec1_008174 C(NC1CCCCCCC1)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D13 compound treatment 31760.0 -15700.0 -0.91 34840.0 -12200.0 -0.92 -1.2924 -1.0 1050866 TimTec1_008175 OCC12COC(N2C(OC1)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D14 compound treatment 34240.0 -13200.0 -0.76 42640.0 -4360.0 -0.33 -0.7733 -0.9297 3212777 TimTec1_008176 CC(CN1CCCC1)OC(=O)COc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D15 compound treatment 37920.0 -9500.0 -0.55 41200.0 -5800.0 -0.44 -0.6997 -0.9937 1782464 TimTec1_008177 CC(=O)Nc1c(O)c2ccccc2oc1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D16 compound treatment 43440.0 -3980.0 -0.23 37520.0 -9480.0 -0.72 -0.6705 -0.8895 3212778 TimTec1_008178 CC(=O)NC1C(=O)Nc2ccc(F)cc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D17 compound treatment 44360.0 -3060.0 -0.18 40400.0 -6600.0 -0.5 -0.4786 -0.9028 3087155 TimTec1_008179 Cc1nc2n(c(C)nc2s1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D18 compound treatment 46920.0 -499.0 -0.03 42200.0 -4800.0 -0.36 -0.2774 -0.7609 3212779 TimTec1_008180 CC(C)N1CC(CC1=O)C(=O)Nc2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D19 compound treatment 49400.0 1980.0 0.11 44640.0 -2360.0 -0.18 -0.0452 -0.2129 3087156 TimTec1_008181 COC(=O)c1ccccc1S(=O)(=O)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D20 compound treatment 27040.0 -20400.0 -1.18 28320.0 -18700.0 -1.41 -1.8348 -0.996 3212780 TimTec1_008182 CN(C)c1ccc(cc1)C(=O)OCC(=O)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D21 compound treatment 43840.0 -3580.0 -0.21 45440.0 -1560.0 -0.12 -0.2302 -0.9645 3087157 TimTec1_008183 CC1CCN(Cc2ccc(N)cc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D22 compound treatment 7920.0 -39500.0 -2.29 12360.0 -34600.0 -2.62 -3.4723 -0.9977 1639443 TimTec1_008184 COc1ccc(cc1)c2csc3ncnc(NCCO)c23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D23 mock treatment 54440.0 7020.0 0.41 46760.0 -241.0 -0.02 0.2747 0.6747 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 D24 mock treatment 52600.0 5180.0 0.3 53320.0 6320.0 0.48 0.5505 0.9748 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E01 compound treatment 43440.0 -3980.0 -0.23 46240.0 -761.0 -0.06 -0.2037 -0.8575 3212781 TimTec1_008185 CC(N1CCOCC1)c2ccc(o2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E02 compound treatment 24560.0 -22900.0 -1.32 22360.0 -24600.0 -1.87 -2.2554 -0.9859 3087158 TimTec1_008186 CCN(Cc1ccccc1)C(=O)C2CCN(Cc3ccc(SC)cc3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E03 compound treatment 38200.0 -9220.0 -0.53 31360.0 -15600.0 -1.18 -1.2149 -0.9353 3212782 TimTec1_008187 CCN(CC)C(=O)c1cc(on1)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E04 compound treatment 46600.0 -819.0 -0.05 47040.0 38.8 0.0 -0.0315 -0.6621 3212783 TimTec1_008188 O=C(NCCc1ccccc1)C(C(=O)c2ccccc2)n3ccccc3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E05 compound treatment 38840.0 -8580.0 -0.5 38280.0 -8720.0 -0.66 -0.8183 -0.9902 3087159 TimTec1_008189 CC1CCCCN1c2ccc(N)cc2C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E06 compound treatment 25440.0 -22000.0 -1.27 33000.0 -14000.0 -1.06 -1.6498 -0.9958 3212784 TimTec1_008190 CCCCN(Cc1ccccc1)C(=O)C2CCN(Cc3cccc(O)c3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E07 compound treatment 22880.0 -24500.0 -1.42 34240.0 -12800.0 -0.97 -1.6883 -0.9823 1203428 TimTec1_008191 OC(=O)CCC(=O)Nc1ccc(cc1)c2cn3ccccc3n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E08 compound treatment 21520.0 -25900.0 -1.5 33240.0 -13800.0 -1.04 -1.7976 -0.9841 1244486 TimTec1_008192 C1C=CC2C1C(Nc3ccccc23)c4ccncc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E09 compound treatment 37080.0 -10300.0 -0.6 37680.0 -9320.0 -0.71 -0.9225 -0.9967 1581355 TimTec1_008193 CCCc1n[nH]c2OC(=C(C#N)C(c12)c3cc(OC)c(OC(=O)C)c(OC)c3)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E10 compound treatment 47440.0 21.3 0.0 45640.0 -1360.0 -0.1 -0.072 -0.6986 1500942 TimTec1_008194 CC1CC(C)(C)OC(O1)C(C)(C)CN(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E11 compound treatment 17120.0 -30300.0 -1.76 17840.0 -29200.0 -2.21 -2.8021 -0.9936 1697639 TimTec1_008195 CC1=C(C(NC(=O)N1)c2ccc(Cl)c(Cl)c2)C(=O)OC3CCCCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E12 compound treatment 13040.0 -34400.0 -1.99 18320.0 -28700.0 -2.17 -2.9436 -0.9991 1171657 TimTec1_008196 CC(NCCN1CCNCC1)c2cc(cc3c2CCC3(C)C)C(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E13 compound treatment 33520.0 -13900.0 -0.81 37360.0 -9640.0 -0.73 -1.0854 -0.9988 1214166 TimTec1_008197 COC(=O)c1c(N)sc2CN(C)CCc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E14 compound treatment 34600.0 -12800.0 -0.74 36480.0 -10500.0 -0.8 -1.0883 -0.9994 1046116 TimTec1_008198 COc1cc(CC=C)c(O)c(CC=C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E15 compound treatment 41200.0 -6220.0 -0.36 43360.0 -3640.0 -0.28 -0.4497 -0.9913 1038723 TimTec1_008199 CCOC(=O)COc1ccc2c(C)cc(=O)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E16 compound treatment 11000.0 -36400.0 -2.11 13480.0 -33500.0 -2.54 -3.2862 -0.9958 3212785 TimTec1_008200 COc1ccc(CNCc2ccc(cc2)N(C)C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E17 compound treatment 48960.0 1540.0 0.09 44920.0 -2080.0 -0.16 -0.0483 -0.2665 3087160 TimTec1_008201 OC(=O)c1cc(on1)c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E18 compound treatment 55320.0 7900.0 0.46 43640.0 -3360.0 -0.25 0.1438 0.2746 3212786 TimTec1_008202 CCN1CCCC1CNCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E19 compound treatment 32480.0 -14900.0 -0.87 29720.0 -17300.0 -1.31 -1.537 -0.9799 3087161 TimTec1_008203 O=C(N1CCCCC1)c2csc(Nc3cccc4ccccc34)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E20 compound treatment 40520.0 -6900.0 -0.4 34720.0 -12300.0 -0.93 -0.94 -0.9289 3212787 TimTec1_008204 C=CCC(NCc1cccs1)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E21 compound treatment 30160.0 -17300.0 -1.0 39840.0 -7160.0 -0.54 -1.0904 -0.9586 3087162 TimTec1_008205 O=c1oc2ccccc2n1CCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E22 compound treatment 47320.0 -98.8 -0.01 48200.0 1200.0 0.09 0.0601 0.6612 3212788 TimTec1_008206 Clc1ccc(OCC(=O)N2CCNCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E23 mock treatment 51080.0 3660.0 0.21 51080.0 4080.0 0.31 0.3683 0.9832 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 E24 mock treatment 50920.0 3500.0 0.2 41880.0 -5120.0 -0.39 -0.1307 -0.2987 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F01 compound treatment 37480.0 -9940.0 -0.58 44120.0 -2880.0 -0.22 -0.5614 -0.9117 1861305 TimTec1_008207 COc1ccc(OCc2nnc(N)s2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F02 compound treatment 37920.0 -9500.0 -0.55 41840.0 -5160.0 -0.39 -0.6654 -0.9859 3087163 TimTec1_008208 Cc1ccc(O)c(CNn2cnnc2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F03 compound treatment 52760.0 5340.0 0.31 42520.0 -4480.0 -0.34 -0.021 -0.0458 3212789 TimTec1_008209 Cc1ccc(C)n1C(Cc2ccccc2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F04 compound treatment 42400.0 -5020.0 -0.29 48520.0 1520.0 0.11 -0.1243 -0.3976 3087164 TimTec1_008210 OC(=O)CCC(=O)Nc1ccc(cc1)C(=O)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F05 compound treatment 36760.0 -10700.0 -0.62 45480.0 -1520.0 -0.12 -0.5181 -0.8247 3212790 TimTec1_008211 CC(C)CNC(=O)C1CCCCC1C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F06 compound treatment 30640.0 -16800.0 -0.97 38960.0 -8040.0 -0.61 -1.1178 -0.9746 1619307 TimTec1_008212 CCCC(=O)Nc1sc2c(CC(C)(C)NC2(C)C)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F07 compound treatment 32960.0 -14500.0 -0.84 40200.0 -6800.0 -0.51 -0.9564 -0.9727 1572925 TimTec1_008213 CC(C)c1cc(C(=O)O)n(n1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F08 compound treatment 30680.0 -16700.0 -0.97 29560.0 -17400.0 -1.32 -1.6193 -0.9885 3087197 TimTec1_008214 CC1CCN(CC1)c2ccc(C#N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F09 compound treatment 32640.0 -14800.0 -0.86 36920.0 -10100.0 -0.76 -1.145 -0.9983 3087198 TimTec1_008215 CC(C)c1ccc(cc1)C(=O)CCN(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F10 compound treatment 30600.0 -16800.0 -0.97 30640.0 -16400.0 -1.24 -1.5648 -0.993 3087199 TimTec1_008216 COC(=O)CC1=C(C(C(=C(N)O1)C#N)c2cccnc2)C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F11 compound treatment 31920.0 -15500.0 -0.9 33520.0 -13500.0 -1.02 -1.3565 -0.998 1226789 TimTec1_008217 NC(Cc1ccccc1)c2ccc3OCCOc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F12 compound treatment 33360.0 -14100.0 -0.81 35040.0 -12000.0 -0.91 -1.2162 -0.9986 3087200 TimTec1_008218 Cc1cc(C)cc(OCC(=O)N2CCCC2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F13 compound treatment 25360.0 -22100.0 -1.28 34200.0 -12800.0 -0.97 -1.5889 -0.9907 3087201 TimTec1_008219 COc1ccc2n3CCN=C(N)c3cc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F14 compound treatment 37360.0 -10100.0 -0.58 37320.0 -9680.0 -0.73 -0.9303 -0.9936 3087202 TimTec1_008220 Clc1ccc(OCC(=O)OCCN2CCOCC2)c(Cl)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F15 compound treatment 29120.0 -18300.0 -1.06 28400.0 -18600.0 -1.41 -1.7453 -0.9902 3087203 TimTec1_008221 CCC(=O)c1[nH]c(C)c(C(=O)CC)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F16 compound treatment 40920.0 -6500.0 -0.38 40720.0 -6280.0 -0.48 -0.6024 -0.9933 3212791 TimTec1_008222 Cc1ccc(SCCC(=O)N2CCC(CC2)C(=O)N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F17 compound treatment 19480.0 -27900.0 -1.62 19880.0 -27100.0 -2.05 -2.5962 -0.9931 3087204 TimTec1_008223 Cc1ccc(NC(=O)C2(CCCC2)c3ccccc3)nc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F18 compound treatment 30960.0 -16500.0 -0.95 31560.0 -15400.0 -1.17 -1.5008 -0.9949 3212792 TimTec1_008224 Cn1c(NCc2ccccc2)nc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F19 compound treatment 38920.0 -8500.0 -0.49 44560.0 -2440.0 -0.18 -0.4788 -0.9105 3212793 TimTec1_008225 CCOc1ccc2[nH]c(=O)c(cc2c1)C(N3CCCCC3)c4nnnn4CCOC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F20 compound treatment 41520.0 -5900.0 -0.34 46880.0 -121.0 -0.01 -0.2482 -0.7258 3087205 TimTec1_008226 O=C(Cc1ccccc1)Nc2ccc3COC(=O)c3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F21 compound treatment 40880.0 -6540.0 -0.38 44200.0 -2800.0 -0.21 -0.4178 -0.9624 3087206 TimTec1_008227 CN1CCc2nc3sc(C(=O)NC(C)(C)C)c(N)c3cc2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F22 compound treatment 46840.0 -579.0 -0.03 43440.0 -3560.0 -0.27 -0.2143 -0.789 1361247 TimTec1_008228 CC1CCN(CC1)C(=O)Cn2cc(C#N)c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F23 mock treatment 54960.0 7540.0 0.44 48680.0 1680.0 0.13 0.3988 0.8764 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 F24 mock treatment 45920.0 -1500.0 -0.09 51520.0 4520.0 0.34 0.1805 0.5114 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G01 compound treatment 30520.0 -16900.0 -0.98 52640.0 5640.0 0.43 -0.3905 -0.3656 3212794 TimTec1_008229 Cc1cc(O)c2n(Cc3ccccc3Cl)nc[n+]2n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G02 compound treatment 23840.0 -23600.0 -1.37 23720.0 -23300.0 -1.76 -2.2121 -0.9921 3087207 TimTec1_008230 CCN(Cc1ccccc1)C(=O)C2CCN(Cc3ccc(cc3)C(F)(F)F)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G03 compound treatment 36760.0 -10700.0 -0.62 35960.0 -11000.0 -0.84 -1.0276 -0.9889 3212795 TimTec1_008231 COC(=O)c1cc(no1)c2ccccn2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G04 compound treatment 44880.0 -2540.0 -0.15 42480.0 -4520.0 -0.34 -0.346 -0.9289 3212865 TimTec1_008232 COc1ccc(Nc2nc(cs2)C(=O)N3CCN(C)CC3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G05 compound treatment 31440.0 -16000.0 -0.93 44400.0 -2600.0 -0.2 -0.7938 -0.8387 3087208 TimTec1_008233 OC(=O)CCN1Cc2ccccc2C1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G06 compound treatment 21640.0 -25800.0 -1.49 34640.0 -12400.0 -0.94 -1.7177 -0.9746 1455909 TimTec1_008234 Cc1nc2ccc(N)cc2c(O)c1CC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G07 compound treatment 15920.0 -31500.0 -1.82 24840.0 -22200.0 -1.68 -2.4766 -0.9991 3212866 TimTec1_008235 O=C(NCc1cccs1)C(C#N)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G08 compound treatment 33000.0 -14400.0 -0.84 36480.0 -10500.0 -0.8 -1.1538 -0.9997 1593691 TimTec1_008236 O=C(N1CCC(C1)c2ccccc2)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G09 compound treatment 42440.0 -4980.0 -0.29 40400.0 -6600.0 -0.5 -0.5573 -0.9659 1260979 TimTec1_008237 CCCCC1CCC(CC1)C2CCC(CC2)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G10 compound treatment 31720.0 -15700.0 -0.91 26840.0 -20200.0 -1.53 -1.7223 -0.9694 3212867 TimTec1_008238 C(CC(c1ccco1)c2ccccc2)NCc3cccs3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G11 compound treatment 25680.0 -21700.0 -1.26 31760.0 -15200.0 -1.15 -1.7064 -0.999 3087209 TimTec1_008239 CCOc1ccc(Cc2c(Cl)nc(SC)nc2Cl)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G12 compound treatment 24000.0 -23400.0 -1.36 31000.0 -16000.0 -1.21 -1.8159 -0.9984 3212868 TimTec1_008240 CCCC1CC(CCO1)c2csc(C)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G13 compound treatment 26000.0 -21400.0 -1.24 25280.0 -21700.0 -1.64 -2.0401 -0.9904 1554032 TimTec1_008241 COc1ccc(Br)cc1CNc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G14 compound treatment 21120.0 -26300.0 -1.52 22720.0 -24300.0 -1.84 -2.377 -0.9957 1199876 TimTec1_008242 CCC1(C)CC(CCO1)C(CCN)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G15 compound treatment 41000.0 -6420.0 -0.37 34840.0 -12200.0 -0.92 -0.9139 -0.9205 1627384 TimTec1_008243 C(CN1CCOCC1)Nc2nc(nc3ccccc23)c4cccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G16 compound treatment 31320.0 -16100.0 -0.93 25440.0 -21600.0 -1.63 -1.8136 -0.9648 3087210 TimTec1_008244 COc1ccc(CNCc2ccncc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G17 compound treatment 45080.0 -2340.0 -0.14 36440.0 -10600.0 -0.8 -0.6611 -0.8153 3212869 TimTec1_008245 Cc1cc2c(ncnc2s1)N3CCC(CC3)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G18 compound treatment 37320.0 -10100.0 -0.59 29560.0 -17400.0 -1.32 -1.3473 -0.933 1721079 TimTec1_008246 COc1ccc(NC(CC=C)c2ccco2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G19 compound treatment 45120.0 -2300.0 -0.13 37960.0 -9040.0 -0.68 -0.5781 -0.8292 3212870 TimTec1_008247 CC(C)(C)NC(=O)C(C(=O)c1ccccc1)n2ccccc2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G20 compound treatment 47360.0 -58.8 0.0 38760.0 -8240.0 -0.62 -0.4435 -0.711 1431012 TimTec1_008248 Clc1ccccc1CNCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G21 compound treatment 36280.0 -11100.0 -0.65 37200.0 -9800.0 -0.74 -0.9809 -0.9976 3212871 TimTec1_008249 CN(Cc1ccccc1)Cc2ccccc2F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G22 compound treatment 43720.0 -3700.0 -0.21 49400.0 2400.0 0.18 -0.0231 -0.0824 3087211 TimTec1_008250 COc1cccc(CNCC(C)O)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G23 mock treatment 43560.0 -3860.0 -0.22 44040.0 -2960.0 -0.22 -0.3166 -1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 G24 mock treatment 44320.0 -3100.0 -0.18 46080.0 -921.0 -0.07 -0.1763 -0.9151 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H01 compound treatment 35840.0 -11600.0 -0.67 51800.0 4800.0 0.36 -0.2175 -0.2851 1585571 TimTec1_008251 OC(=O)CSCC(=O)N1CCCCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H02 compound treatment 42520.0 -4900.0 -0.28 38560.0 -8440.0 -0.64 -0.6525 -0.9333 3212872 TimTec1_008252 CC1(C)CC(=O)C2=C(C1)OC(=C(C#N)C32C(=O)N(CCc4ccccc4)c5ccccc53)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H03 compound treatment 47000.0 -419.0 -0.02 42920.0 -4080.0 -0.31 -0.2356 -0.7603 1125791 TimTec1_008253 O=C(C(c1ccccc1)c2ccccc2)N3CCNCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H04 compound treatment 42200.0 -5220.0 -0.3 48520.0 1520.0 0.11 -0.1325 -0.4096 3212873 TimTec1_008254 OC1=C(C(NC1=O)c2ccccc2)C(=O)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H05 compound treatment 25120.0 -22300.0 -1.29 43280.0 -3720.0 -0.28 -1.1127 -0.8415 3087212 TimTec1_008255 OC(=O)CN1CCC(CC1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H06 compound treatment 25880.0 -21500.0 -1.25 35440.0 -11600.0 -0.88 -1.5012 -0.9849 3212874 TimTec1_008256 CC1(C)Cc2c(C#N)c(NC(=O)Cc3ccccc3)sc2C(C)(C)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H07 compound treatment 8240.0 -39200.0 -2.27 13000.0 -34000.0 -2.57 -3.425 -0.998 3087213 TimTec1_008257 CC(C)OC(=O)c1cc2nc(cc(n2n1)C(F)(F)F)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H08 compound treatment 37320.0 -10100.0 -0.59 33440.0 -13600.0 -1.03 -1.1396 -0.9645 3212875 TimTec1_008258 CC(C)OC(=O)Cn1cc(C#N)c2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H09 compound treatment 26480.0 -20900.0 -1.21 23160.0 -23800.0 -1.8 -2.1339 -0.9813 1699078 TimTec1_008259 Oc1c(CN2CCOCC2)ccc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H10 compound treatment 12960.0 -34500.0 -2.0 15600.0 -31400.0 -2.38 -3.0924 -0.9962 3212876 TimTec1_008260 NC1=C(C#N)C2(C(=O)N(CCc3ccccc3)c4ccccc42)C(=C(N)S1)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H11 compound treatment 35440.0 -12000.0 -0.69 30080.0 -16900.0 -1.28 -1.3964 -0.9586 1431998 TimTec1_008261 Brc1ccc2n(CCC#N)c(=O)oc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H12 compound treatment 30400.0 -17000.0 -0.99 29480.0 -17500.0 -1.33 -1.635 -0.9893 3212877 TimTec1_008262 CC1CCCC(C)N1C(=O)Cc2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H13 compound treatment 31000.0 -16400.0 -0.95 33280.0 -13700.0 -1.04 -1.4071 -0.999 1131527 TimTec1_008263 CC1(C)Cc2ccccc2C(CC=C)N1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H14 compound treatment 39960.0 -7460.0 -0.43 39960.0 -7040.0 -0.53 -0.6824 -0.9946 1862477 TimTec1_008264 CC(C)C(=O)Nc1ccc(CN2CCOCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H15 compound treatment 42640.0 -4780.0 -0.28 36800.0 -10200.0 -0.77 -0.7418 -0.9043 1243642 TimTec1_008265 OC(=O)C(Cc1ccc(F)cc1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H16 compound treatment 33920.0 -13500.0 -0.78 29640.0 -17400.0 -1.31 -1.4823 -0.9693 1432046 TimTec1_008266 CCc1cc2c(NCCO)ncnc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H17 compound treatment 46160.0 -1260.0 -0.07 39760.0 -7240.0 -0.55 -0.4391 -0.7942 1786471 TimTec1_008267 CN1CCN(CC2COc3ccccc3O2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H18 compound treatment 37440.0 -9980.0 -0.58 33880.0 -13100.0 -0.99 -1.1111 -0.9668 3087214 TimTec1_008268 C=CCn1c(NCc2ccccc2)nc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H19 compound treatment 43680.0 -3740.0 -0.22 41120.0 -5880.0 -0.45 -0.468 -0.9452 1125869 TimTec1_008269 Brc1ccc(OCC(=O)OCC(=O)c2ccccc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H20 compound treatment 41160.0 -6260.0 -0.36 41920.0 -5080.0 -0.38 -0.5284 -0.9996 1178508 TimTec1_008270 CCC(=O)OC1(C(C)CN(C)CC1C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H21 compound treatment 46360.0 -1060.0 -0.06 45000.0 -2000.0 -0.15 -0.1505 -0.9208 3212878 TimTec1_008271 COCc1[nH]nc2OC(=C(C#N)C(c12)c3ccc(OCC(=O)N)c(OC)c3)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H22 compound treatment 43560.0 -3860.0 -0.22 42000.0 -5000.0 -0.38 -0.4258 -0.9684 1513547 TimTec1_008272 COc1cccc2c(=O)c3n(C)ncc3n(C)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H23 mock treatment 51200.0 3780.0 0.22 49840.0 2840.0 0.21 0.3069 1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 H24 mock treatment 46000.0 -1420.0 -0.08 45320.0 -1680.0 -0.13 -0.1481 -0.9776 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I01 compound treatment 12560.0 -34900.0 -2.02 24160.0 -22800.0 -1.73 -2.6507 -0.997 1283957 TimTec1_008273 CC(=O)Nc1ccccc1c2nc3ccccc3s2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I02 compound treatment 39080.0 -8340.0 -0.48 46160.0 -841.0 -0.06 -0.3867 -0.7934 3087215 TimTec1_008274 CC(C)NC(=O)C1CCN(Cc2ccc(C)cc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I03 compound treatment 46320.0 -1100.0 -0.06 44400.0 -2600.0 -0.2 -0.1842 -0.8903 3212879 TimTec1_008275 COC(=O)c1cc(no1)c2ccccc2C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I04 compound treatment 15680.0 -31700.0 -1.84 19080.0 -27900.0 -2.11 -2.7947 -0.9976 3212880 TimTec1_008276 Cc1ccc(Nc2nc(cs2)C(=O)N(CC=C)CC=C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I05 compound treatment 26920.0 -20500.0 -1.19 40440.0 -6560.0 -0.5 -1.191 -0.9252 3087216 TimTec1_008277 OC(=O)CC(CC(=O)Nc1nncs1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I06 compound treatment 25320.0 -22100.0 -1.28 37520.0 -9480.0 -0.72 -1.4128 -0.9626 3212881 TimTec1_008278 OC(=O)c1cc(on1)c2ccccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I07 compound treatment 32280.0 -15100.0 -0.88 40800.0 -6200.0 -0.47 -0.9521 -0.9571 3087217 TimTec1_008279 CCC(=O)Nc1cc(ccc1N2CCOCC2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I08 compound treatment 40960.0 -6460.0 -0.37 35360.0 -11600.0 -0.88 -0.8877 -0.9272 3212882 TimTec1_008280 CC(=O)OC1CCCCC1C2=CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I09 compound treatment 20040.0 -27400.0 -1.59 24200.0 -22800.0 -1.73 -2.3421 -0.9991 1632793 TimTec1_008281 Cc1sc2ncnc(Nc3ccccc3)c2c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I10 compound treatment 27440.0 -20000.0 -1.16 34520.0 -12500.0 -0.94 -1.4865 -0.9949 3212883 TimTec1_008282 CCCCc1nc2ccccc2c(N)c1CC.OCC(O)C1OC(=O)C(=C1O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I11 compound treatment 4560.0 -42900.0 -2.48 3600.0 -43400.0 -3.29 -4.0789 -0.9905 1288391 TimTec1_008283 CC1CCCC(C1)OC(=O)C2=C(C)N(C)C(=O)NC2c3ccccc3Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I12 compound treatment 30440.0 -17000.0 -0.98 27920.0 -19100.0 -1.44 -1.7169 -0.9825 3087218 TimTec1_008284 CCN(CC)CCCOc1cccc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I13 compound treatment 14360.0 -33100.0 -1.92 16960.0 -30000.0 -2.27 -2.9623 -0.9964 3087219 TimTec1_008285 CCCC1C(=C(N)SC(=C1C#N)N)C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I14 compound treatment 36320.0 -11100.0 -0.64 33440.0 -13600.0 -1.03 -1.1805 -0.9746 3212884 TimTec1_008286 Cc1nn(CC=C)cc1Cc2cn(CC=C)nc2C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I15 compound treatment 47720.0 301.0 0.02 40800.0 -6200.0 -0.47 -0.3196 -0.6803 3212885 TimTec1_008287 CCc1ccc(cc1)C2N(CC3CCCO3)C(=O)C(=C2C(=O)c4ccco4)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I16 compound treatment 28880.0 -18500.0 -1.07 23720.0 -23300.0 -1.76 -2.0056 -0.9718 1437719 TimTec1_008288 C=CCC(NCCc1ccccc1)c2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I17 compound treatment 52960.0 5540.0 0.32 45040.0 -1960.0 -0.15 0.122 0.345 3087220 TimTec1_008289 OC(=O)c1cc2[nH]c3CCCCc3c2cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I18 compound treatment 40520.0 -6900.0 -0.4 41840.0 -5160.0 -0.39 -0.5589 -0.9999 3212886 TimTec1_008290 CC1(C)CC(CC(C)(C)N1)NCc2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I19 compound treatment 49800.0 2380.0 0.14 40440.0 -6560.0 -0.5 -0.2536 -0.492 3211182 TimTec1_008291 O=C(NCc1ccccc1)C(C(=O)c2ccccc2)n3ccccc3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I20 compound treatment 44760.0 -2660.0 -0.15 44440.0 -2560.0 -0.19 -0.246 -0.9935 3087221 TimTec1_008292 Fc1ccc(CNCCN2CCOCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I21 compound treatment 45520.0 -1900.0 -0.11 38640.0 -8360.0 -0.63 -0.5253 -0.8178 3211183 TimTec1_008293 COc1cccc(CN2CCC(CC2)C(=O)N3CCc4ccccc4C3)c1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I22 compound treatment 48880.0 1460.0 0.08 47880.0 879.0 0.07 0.1069 0.9929 1485172 TimTec1_008294 CCN(CC)CCNC1CCN(C)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I23 mock treatment 46480.0 -939.0 -0.05 42880.0 -4120.0 -0.31 -0.259 -0.818 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 I24 mock treatment 42360.0 -5060.0 -0.29 48880.0 1880.0 0.14 -0.1067 -0.3275 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J01 compound treatment 48320.0 901.0 0.05 52000.0 5000.0 0.38 0.3045 0.7971 1316790 TimTec1_008295 CC1CCCC(C)N1C(=O)CCC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J02 compound treatment 1680.0 -45700.0 -2.65 2160.0 -44800.0 -3.39 -4.2739 -0.9925 1111854 TimTec1_008296 Cc1ccc2[nH]c(nc2c1)c3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J03 compound treatment 51880.0 4460.0 0.26 44920.0 -2080.0 -0.16 0.0714 0.2358 3211184 TimTec1_008297 OC(=O)C1CC=CCC1C(=O)NCc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J04 compound treatment 25280.0 -22100.0 -1.28 31640.0 -15400.0 -1.16 -1.7292 -0.9988 3087222 TimTec1_008298 Clc1ccc(OCCn2ccccc2=O)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J05 compound treatment 24200.0 -23200.0 -1.35 38800.0 -8200.0 -0.62 -1.3902 -0.9383 3211185 TimTec1_008299 CC(C)(C)C1CC(n2nc(cc2N1)C(=O)O)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J06 compound treatment 8560.0 -38900.0 -2.25 20760.0 -26200.0 -1.99 -2.9965 -0.998 3087264 TimTec1_008300 CC1(CC2CC(C)(C)C1)CN2C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J07 compound treatment 20800.0 -26600.0 -1.54 32000.0 -15000.0 -1.14 -1.8934 -0.9887 1784956 TimTec1_008301 CCCCC(CC)C(=O)Nc1ccc(C#N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J08 compound treatment 39720.0 -7700.0 -0.45 41920.0 -5080.0 -0.38 -0.5874 -0.9973 3087265 TimTec1_008302 CCOc1cc(CO)ccc1OCC(=O)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J09 compound treatment 18840.0 -28600.0 -1.66 24560.0 -22400.0 -1.7 -2.372 -0.9999 3087266 TimTec1_008303 O=C(Nc1nonc1OCCOc2nonc2NC(=O)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J10 compound treatment 15120.0 -32300.0 -1.87 15360.0 -31600.0 -2.4 -3.0168 -0.9925 3087267 TimTec1_008304 N#Cc1cn(CCCOc2ccccc2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J11 compound treatment 11680.0 -35700.0 -2.07 10040.0 -37000.0 -2.8 -3.4425 -0.989 1740843 TimTec1_008305 CCOC(=O)C1=C(N)c2ccccc2CC31CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J12 compound treatment 27520.0 -19900.0 -1.15 33000.0 -14000.0 -1.06 -1.5646 -0.9991 3087268 TimTec1_008306 CCOC(=O)[C@@H]1CSC(N1)c2ccc(OC)c(OC)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J13 compound treatment 37000.0 -10400.0 -0.6 42320.0 -4680.0 -0.35 -0.6774 -0.9678 3087269 TimTec1_008307 CC(=O)Nc1nc2nc(cc(O)n2n1)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J14 compound treatment 37960.0 -9460.0 -0.55 35120.0 -11900.0 -0.9 -1.0234 -0.9718 3211186 TimTec1_008308 CCCn1nnc(NC(=O)COc2ccccc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J15 compound treatment 45840.0 -1580.0 -0.09 39480.0 -7520.0 -0.57 -0.4672 -0.8103 1488887 TimTec1_008309 CC1(C)CC(=CC(C)(C)N1)c2c[nH]c(c2)C3=CC(C)(C)NC(C)(C)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J16 compound treatment 41960.0 -5460.0 -0.32 34800.0 -12200.0 -0.92 -0.8767 -0.8981 3087270 TimTec1_008310 Oc1ncnc2n(Cc3ccc(F)cc3)nnc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J17 compound treatment 43680.0 -3740.0 -0.22 38960.0 -8040.0 -0.61 -0.5836 -0.9033 1236834 TimTec1_008311 CC(=O)NC1CCC(C1)(C(=O)O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J18 compound treatment 27760.0 -19700.0 -1.14 28200.0 -18800.0 -1.42 -1.8117 -0.9939 1179590 TimTec1_008312 CCC(CO)NC(=O)c1cc2sc3ccccc3c2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J19 compound treatment 33080.0 -14300.0 -0.83 32400.0 -14600.0 -1.11 -1.3689 -0.9901 1729523 TimTec1_008313 Cc1nc(C)c(CC=C)c(NCCO)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J20 compound treatment 25200.0 -22200.0 -1.29 23560.0 -23400.0 -1.77 -2.1649 -0.9876 3087271 TimTec1_008314 Cc1ccc(NCc2ccc(O)c3ncccc23)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J21 compound treatment 48880.0 1460.0 0.08 48080.0 1080.0 0.08 0.1176 0.9998 3211187 TimTec1_008315 Nc1c(C#N)sc2nc(cc(c12)C(F)(F)F)c3ccncc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J22 compound treatment 45960.0 -1460.0 -0.08 43280.0 -3720.0 -0.28 -0.2589 -0.8805 3087272 TimTec1_008316 O=C(CS(=O)(=O)Cc1ccccc1)Nc2nccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J23 mock treatment 44480.0 -2940.0 -0.17 46320.0 -681.0 -0.05 -0.1569 -0.8817 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 J24 mock treatment 49440.0 2020.0 0.12 42760.0 -4240.0 -0.32 -0.1442 -0.422 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K01 compound treatment 42960.0 -4460.0 -0.26 55600.0 8600.0 0.65 0.2776 0.3964 3211188 TimTec1_008317 O=C(Nc1cccnc1)c2cc(on2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K02 compound treatment 36840.0 -10600.0 -0.61 34640.0 -12400.0 -0.94 -1.095 -0.979 3211189 TimTec1_008318 COc1ccc(CN2CCC(CC2)C(=O)NC3CCCC3)cc1OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K03 compound treatment 30200.0 -17200.0 -1.0 27040.0 -20000.0 -1.51 -1.7738 -0.9797 1391647 TimTec1_008319 COC(=O)c1cc(no1)c2ccc(OCc3ccccc3)c(OC)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K04 compound treatment 21480.0 -25900.0 -1.5 37960.0 -9040.0 -0.68 -1.5466 -0.9366 1291005 TimTec1_008320 CC(C)NC(=O)CC1Nc2ccccc2NC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K05 compound treatment 17440.0 -30000.0 -1.74 30160.0 -16800.0 -1.27 -2.1296 -0.9884 3087273 TimTec1_008321 OC(=O)C(N1CCCCC1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K06 compound treatment 9960.0 -37500.0 -2.17 21600.0 -25400.0 -1.92 -2.8942 -0.9982 3211190 TimTec1_008322 Nc1ncc(c2ccccc2)n1CC3CCCO3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K07 compound treatment 35080.0 -12300.0 -0.71 36760.0 -10200.0 -0.78 -1.0536 -0.9992 3211191 TimTec1_008323 C(NCc1ccco1)C2CC3CC2C=C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K08 compound treatment 31720.0 -15700.0 -0.91 35560.0 -11400.0 -0.87 -1.2555 -0.9997 3087274 TimTec1_008324 CC(Sc1ccc(C)cc1)C(=O)NCC2CCCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K09 compound treatment 33560.0 -13900.0 -0.8 29760.0 -17200.0 -1.31 -1.4906 -0.9728 3211192 TimTec1_008325 COC(=O)C1=C(C)C(NC(=O)N1)c2ccc(OC)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K10 compound treatment 25040.0 -22400.0 -1.3 26280.0 -20700.0 -1.57 -2.0259 -0.9955 3087275 TimTec1_008326 CC1COC(OC1)C2C(C)CC(=CC2C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K11 compound treatment 21880.0 -25500.0 -1.48 28800.0 -18200.0 -1.38 -2.0205 -0.9994 1256258 TimTec1_008327 O=C(CN1C(=O)c2ccccc2C1=O)Oc3ccc4ccccc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K12 compound treatment 21040.0 -26400.0 -1.53 24680.0 -22300.0 -1.69 -2.2754 -0.9987 1145508 TimTec1_008328 CC(CC1OCC(CN2CCCCC2)O1)CC(C)(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K13 compound treatment 30200.0 -17200.0 -1.0 32480.0 -14500.0 -1.1 -1.4827 -0.9988 1142153 TimTec1_008329 COC(=O)c1ccc(CNC(C)(C)C)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K14 compound treatment 35640.0 -11800.0 -0.68 29520.0 -17500.0 -1.32 -1.4182 -0.9526 1277743 TimTec1_008330 CCC1(C)CC(CCN)(CCO1)c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K15 compound treatment 31800.0 -15600.0 -0.9 32000.0 -15000.0 -1.14 -1.4428 -0.9937 1433041 TimTec1_008331 OC(=O)c1c(sc2CCCCc12)n3cccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K16 compound treatment 30520.0 -16900.0 -0.98 30360.0 -16600.0 -1.26 -1.583 -0.9922 1402408 TimTec1_008332 NC(Cc1ccccc1)C(O)(CC=C)CC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K17 compound treatment 33040.0 -14400.0 -0.83 27880.0 -19100.0 -1.45 -1.6125 -0.9656 3211193 TimTec1_008333 Cc1ccc(C(=O)NCc2ccco2)c(C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K18 compound treatment 34960.0 -12500.0 -0.72 34240.0 -12800.0 -0.97 -1.1934 -0.9897 1696859 TimTec1_008334 C(NCc1ccc2OCOc2c1)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K19 compound treatment 36760.0 -10700.0 -0.62 37240.0 -9760.0 -0.74 -0.9591 -0.996 3211194 TimTec1_008335 O=C(NC1CCCCC1)C(C(=O)c2ccccc2)n3ccccc3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K20 compound treatment 33840.0 -13600.0 -0.79 33720.0 -13300.0 -1.01 -1.2672 -0.9926 1125091 TimTec1_008336 CCc1ccc(CNCC2CCCO2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K21 compound treatment 32960.0 -14500.0 -0.84 33080.0 -13900.0 -1.05 -1.3375 -0.9935 3211195 TimTec1_008337 CCN(CC)C(=O)C1CCN(Cc2ccc(Br)cc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K22 compound treatment 38320.0 -9100.0 -0.53 31800.0 -15200.0 -1.15 -1.1864 -0.9374 3087276 TimTec1_008338 CC(N1CCNCC1)c2ccc(C)c(C)c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K23 mock treatment 40600.0 -6820.0 -0.4 39800.0 -7200.0 -0.55 -0.6648 -0.9875 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 K24 mock treatment 35280.0 -12100.0 -0.7 38520.0 -8480.0 -0.64 -0.9513 -0.999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L01 compound treatment 32720.0 -14700.0 -0.85 46160.0 -841.0 -0.06 -0.6472 -0.7579 1503250 TimTec1_008339 COc1ccccc1C(=O)N2CCNCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L02 compound treatment 41280.0 -6140.0 -0.36 39680.0 -7320.0 -0.55 -0.6434 -0.977 3087277 TimTec1_008340 Clc1cccc(CNCc2ccco2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L03 compound treatment 46160.0 -1260.0 -0.07 47800.0 799.0 0.06 -0.0088 -0.0931 1788809 TimTec1_008341 OC(=O)CCCC(=O)Nc1ccccc1n2ccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L04 compound treatment 16760.0 -30700.0 -1.78 36000.0 -11000.0 -0.83 -1.8449 -0.9404 3211196 TimTec1_008342 O=C(CCCOc1ccccc1)Nc2nncs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L05 compound treatment 20080.0 -27300.0 -1.58 41600.0 -5400.0 -0.41 -1.4091 -0.8614 3087278 TimTec1_008343 CCc1ccc(cc1)c2nc(N)sc2CC(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L06 compound treatment 25120.0 -22300.0 -1.29 34560.0 -12400.0 -0.94 -1.5794 -0.9879 3211197 TimTec1_008344 CCCC(=O)N(CC)Cc1cc2cc(OC)ccc2nc1O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L07 compound treatment 43440.0 -3980.0 -0.23 41400.0 -5600.0 -0.42 -0.4628 -0.959 3087279 TimTec1_008345 FC(F)(F)C(=O)N1CCN(CC1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L08 compound treatment 34920.0 -12500.0 -0.72 37760.0 -9240.0 -0.7 -1.0067 -0.9999 3211198 TimTec1_008346 C(N1CCN(CC1)c2ccccn2)c3cn4ccccc4n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L09 compound treatment 26520.0 -20900.0 -1.21 30160.0 -16800.0 -1.27 -1.7576 -0.9997 1481135 TimTec1_008347 COC(=O)c1ccc(Oc2cc(cc(c2)C(=O)OC)C(=O)OC)c(N)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L10 compound treatment 25240.0 -22200.0 -1.28 32680.0 -14300.0 -1.08 -1.6752 -0.9964 1245186 TimTec1_008348 CC1CCCCN1C(=O)Cn2c(C)c(C#N)c3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L11 compound treatment 16680.0 -30700.0 -1.78 24120.0 -22900.0 -1.73 -2.484 -0.9999 1471585 TimTec1_008349 O=S(=O)(c1nc(oc1N2CCCCC2)c3ccco3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L12 compound treatment 32320.0 -15100.0 -0.87 34280.0 -12700.0 -0.96 -1.2995 -0.9989 3087280 TimTec1_008350 CN1CCC(CC1)OC(=O)c2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L13 compound treatment 11560.0 -35900.0 -2.08 14040.0 -33000.0 -2.49 -3.2333 -0.9959 3087281 TimTec1_008351 CCc1ccc(nc1)c2ccc(C#N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L14 compound treatment 39520.0 -7900.0 -0.46 34680.0 -12300.0 -0.93 -0.9831 -0.9463 3211199 TimTec1_008352 CCCOc1cccc(c1)C(=O)Nc2nnn(C)n2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L15 compound treatment 37880.0 -9540.0 -0.55 38040.0 -8960.0 -0.68 -0.8704 -0.9948 3087282 TimTec1_008353 CCOC(=O)c1ncn2c1C(=O)OC2(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L16 compound treatment 32160.0 -15300.0 -0.88 29120.0 -17900.0 -1.35 -1.5822 -0.9787 3211200 TimTec1_008354 Cc1ccc(cc1)C2SC(=O)NC3=C2C(=O)c4ccccc34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L17 compound treatment 48600.0 1180.0 0.07 40880.0 -6120.0 -0.46 -0.2792 -0.5962 1784411 TimTec1_008355 CN(C)CC(O)COc1cccc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L18 compound treatment 34760.0 -12700.0 -0.73 39120.0 -7880.0 -0.6 -0.9404 -0.9947 3211201 TimTec1_008356 COC(=O)Cn1c(Cc2ccccc2)nc3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L19 compound treatment 35440.0 -12000.0 -0.69 32440.0 -14600.0 -1.1 -1.2701 -0.9751 3211386 TimTec1_008357 CCCc1nc2sc3CCCCc3c2c(=O)[nH]1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L20 compound treatment 14440.0 -33000.0 -1.91 15120.0 -31900.0 -2.41 -3.0575 -0.9933 3087283 TimTec1_008358 COc1cccc(NCc2ccc(O)c3ncccc23)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L21 compound treatment 25440.0 -22000.0 -1.27 32600.0 -14400.0 -1.09 -1.6712 -0.997 1186739 TimTec1_008359 Nc1ccc(cc1N2CCCCC2)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L22 compound treatment 43240.0 -4180.0 -0.24 43200.0 -3800.0 -0.29 -0.3747 -0.9963 3087284 TimTec1_008360 CC1CCc2c(NCCC3CCCN3C)n4ncnc4nc2C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L23 mock treatment 48280.0 861.0 0.05 43480.0 -3520.0 -0.27 -0.1532 -0.5649 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 L24 mock treatment 47560.0 141.0 0.01 43000.0 -4000.0 -0.3 -0.2084 -0.6877 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M01 compound treatment 16840.0 -30600.0 -1.77 24480.0 -22500.0 -1.7 -2.4582 -0.9998 3211387 TimTec1_008361 O=C(N1CCCC1)c2cc(on2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M02 compound treatment 42840.0 -4580.0 -0.27 42840.0 -4160.0 -0.31 -0.4103 -0.9964 3211388 TimTec1_008362 COc1cccc(CN2CCC(CC2)C(=O)NC(C)C)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M03 compound treatment 39040.0 -8380.0 -0.49 34160.0 -12800.0 -0.97 -1.0306 -0.9485 1578709 TimTec1_008363 CC(C)Oc1snc(Cl)c1C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M04 compound treatment 11520.0 -35900.0 -2.08 23840.0 -23200.0 -1.75 -2.7104 -0.9964 1479613 TimTec1_008364 CCOC(=O)c1cc(CC)sc1NC(=O)CC2Nc3ccccc3NC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M05 compound treatment 20320.0 -27100.0 -1.57 32080.0 -14900.0 -1.13 -1.9088 -0.9869 3087285 TimTec1_008365 Cc1ccc(OCC(=O)Oc2ccccn2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M06 compound treatment 30000.0 -17400.0 -1.01 40760.0 -6240.0 -0.47 -1.0477 -0.9402 3211389 TimTec1_008366 OC(=O)C1C2OC3(CN(Cc4ccncc4)C(=O)C13)C=C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M07 compound treatment 19400.0 -28000.0 -1.62 25040.0 -22000.0 -1.66 -2.3233 -0.9999 1127485 TimTec1_008367 OC(=O)CC1Nc2ccccc2NC1=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M08 compound treatment 21400.0 -26000.0 -1.51 27800.0 -19200.0 -1.45 -2.0937 -0.9998 1124983 TimTec1_008368 CCC(=O)N(CCC(C1CCOC(C)(C)C1)c2ccccc2)Cc3ccc(OC)cc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M09 compound treatment 21800.0 -25600.0 -1.48 30480.0 -16500.0 -1.25 -1.9338 -0.9964 3087286 TimTec1_008369 COC(=O)CN1C(c2ccccc2)c3cc(Br)ccc3N=C1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M10 compound treatment 23760.0 -23700.0 -1.37 33280.0 -13700.0 -1.04 -1.7037 -0.9906 3211390 TimTec1_008370 CCn1ncc(Cc2cnn(CC)c2C)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M11 compound treatment 30360.0 -17100.0 -0.99 36720.0 -10300.0 -0.78 -1.2492 -0.993 3211391 TimTec1_008371 OC(=O)c1cccc(c1)c2ccc(/C=C\3/SC(=O)N(C3=O)c4ccccc4)o2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M12 compound treatment 26320.0 -21100.0 -1.22 27800.0 -19200.0 -1.45 -1.8921 -0.9963 3087287 TimTec1_008372 CC1=CCC2COC(C1C2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M13 compound treatment 32640.0 -14800.0 -0.86 35360.0 -11600.0 -0.88 -1.2285 -0.9999 1012735 TimTec1_008373 CCOC(=O)c1c(C)[nH]c(C(=O)O)c1C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M14 compound treatment 39480.0 -7940.0 -0.46 38040.0 -8960.0 -0.68 -0.8049 -0.9821 3211392 TimTec1_008374 Cc1ccccc1CNCc2cccnc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M15 compound treatment 41000.0 -6420.0 -0.37 39240.0 -7760.0 -0.59 -0.6784 -0.9757 3087288 TimTec1_008375 CN1CCN(CC1)C(=O)Cc2ccc(F)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M16 compound treatment 28200.0 -19200.0 -1.11 27160.0 -19800.0 -1.5 -1.8493 -0.9892 1676992 TimTec1_008376 CNCC(O)COc1cccc(OC)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M17 compound treatment 1920.0 -45500.0 -2.64 2040.0 -45000.0 -3.4 -4.2705 -0.992 3211393 TimTec1_008377 O=C(NCc1ccc(cc1)c2nc3ccccc3s2)c4cccnc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M18 compound treatment 37920.0 -9500.0 -0.55 40480.0 -6520.0 -0.49 -0.7382 -0.9985 3087289 TimTec1_008378 Cc1ccc(CNCCN2CCOCC2)o1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M19 compound treatment 32720.0 -14700.0 -0.85 34040.0 -13000.0 -0.98 -1.2959 -0.9975 3211394 TimTec1_008379 CN(Cc1cn[nH]c1c2ccc(C)cc2)Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M20 compound treatment 41240.0 -6180.0 -0.36 40440.0 -6560.0 -0.5 -0.6043 -0.9871 1168279 TimTec1_008380 CN1CCC(CC1)NCc2ccccc2Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M21 compound treatment 34080.0 -13300.0 -0.77 32600.0 -14400.0 -1.09 -1.3173 -0.9858 3211395 TimTec1_008381 CCN(Cc1ccccc1)C(=O)C2CCN(Cc3ccc(OC)cc3)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M22 compound treatment 36280.0 -11100.0 -0.65 40320.0 -6680.0 -0.51 -0.8139 -0.9927 3087290 TimTec1_008382 OC(=O)CCC(=O)Nc1ccc(CN2CCCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M23 mock treatment 42040.0 -5380.0 -0.31 32960.0 -14000.0 -1.06 -0.9719 -0.8775 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 M24 mock treatment 43920.0 -3500.0 -0.2 43040.0 -3960.0 -0.3 -0.3554 -0.9818 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N01 compound treatment 28560.0 -18900.0 -1.09 49600.0 2600.0 0.2 -0.6335 -0.5706 3211396 TimTec1_008383 CC(O)CNCc1cccc2ccccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N02 compound treatment 42760.0 -4660.0 -0.27 40120.0 -6880.0 -0.52 -0.5592 -0.9532 3087291 TimTec1_008384 C(NCc1cccc2ccccc12)c3ccco3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N03 compound treatment 43440.0 -3980.0 -0.23 40800.0 -6200.0 -0.47 -0.4949 -0.9464 3211397 TimTec1_008385 CC(=O)N1C(Cc2c([nH]c3ccccc23)C1(C)C)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N04 compound treatment 8040.0 -39400.0 -2.28 17000.0 -30000.0 -2.27 -3.2191 -1.0 3087292 TimTec1_008386 CC(C)(Oc1ccc(Cl)cc1)C(=O)N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N05 compound treatment 15960.0 -31500.0 -1.82 26000.0 -21000.0 -1.59 -2.4129 -0.9977 1389054 TimTec1_008387 C1CN(CCO1)c2cc(nc(n2)c3ccccc3)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N06 compound treatment 25280.0 -22100.0 -1.28 32560.0 -14400.0 -1.09 -1.6799 -0.9968 1256237 TimTec1_008388 Nc1ccc2nc(CCCc3nc4ccc(N)cc4s3)sc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N07 compound treatment 19280.0 -28100.0 -1.63 28680.0 -18300.0 -1.39 -2.1334 -0.9968 1651407 TimTec1_008389 CCOC(=O)c1ccc(cc1)N2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N08 compound treatment 16520.0 -30900.0 -1.79 23480.0 -23500.0 -1.78 -2.5248 -1.0 3087340 TimTec1_008390 FC(F)(F)c1cccc(NCc2cn3ccccc3n2)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N09 compound treatment 11280.0 -36100.0 -2.09 23080.0 -23900.0 -1.81 -2.7609 -0.9974 1133793 TimTec1_008391 NC(=S)c1cc2cccc(CC=C)c2oc1=N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N10 compound treatment 7000.0 -40400.0 -2.34 11360.0 -35600.0 -2.7 -3.5635 -0.9975 3087341 TimTec1_008392 Oc1ccc(CNc2cccc(Cl)c2)c3cccnc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N11 compound treatment 20040.0 -27400.0 -1.59 35360.0 -11600.0 -0.88 -1.7447 -0.9615 1331799 TimTec1_008393 O=C(N1CCCn2c1nc3ccccc23)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N12 compound treatment 29120.0 -18300.0 -1.06 37200.0 -9800.0 -0.74 -1.2743 -0.9848 3087342 TimTec1_008394 COc1ccc(cc1)C(=O)OC(C)CN2CCN(C)CC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N13 compound treatment 31960.0 -15500.0 -0.9 31280.0 -15700.0 -1.19 -1.4748 -0.9902 1365632 TimTec1_008395 OC1=C(C(C2=C(O)CCCC2=O)c3ccccc3)C(=O)CCC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N14 compound treatment 31000.0 -16400.0 -0.95 34520.0 -12500.0 -0.94 -1.3407 -1.0 3211398 TimTec1_008396 CCCC(=O)Nc1ccc2oc(=O)ccc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N15 compound treatment 28360.0 -19100.0 -1.1 28840.0 -18200.0 -1.37 -1.7529 -0.9941 1175335 TimTec1_008397 OC1(C#CCN2CCCCC2)C3CCCC3c4ccccc41 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N16 compound treatment 14680.0 -32700.0 -1.9 16400.0 -30600.0 -2.32 -2.9791 -0.9951 1871509 TimTec1_008398 CCNc1nnc(s1)c2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N17 compound treatment 12080.0 -35300.0 -2.05 15640.0 -31400.0 -2.37 -3.1263 -0.9973 1297935 TimTec1_008399 CSc1nc(C)c(CC=C)c(Nc2ccccc2)n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N18 compound treatment 34800.0 -12600.0 -0.73 38400.0 -8600.0 -0.65 -0.9773 -0.9983 3087343 TimTec1_008400 Clc1ccc(OCC(=O)n2cnnc2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N19 compound treatment 17600.0 -29800.0 -1.73 17200.0 -29800.0 -2.26 -2.8167 -0.9913 1787965 TimTec1_008401 COc1cc(ccc1OCc2ccccc2)c3cc(C#N)on3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N20 compound treatment 37000.0 -10400.0 -0.6 36160.0 -10800.0 -0.82 -1.0071 -0.9886 3087344 TimTec1_008402 COc1ccc(cc1OC)C(=O)OCC(=O)Nc2sc3CCCc3c2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N21 compound treatment 7800.0 -39600.0 -2.3 6000.0 -41000.0 -3.1 -3.8177 -0.989 3211399 TimTec1_008403 CC(C)N1CCCc2cc(CN)ccc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N22 compound treatment 2640.0 -44800.0 -2.59 2440.0 -44600.0 -3.37 -4.2196 -0.9916 1235712 TimTec1_008404 CC1=C(C(c2ccco2)c3c(N)c(C#N)sc3N1)C(=O)OCC=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N23 mock treatment 43320.0 -4100.0 -0.24 43280.0 -3720.0 -0.28 -0.3671 -0.9964 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 N24 mock treatment 41880.0 -5540.0 -0.32 42960.0 -4040.0 -0.31 -0.4432 -0.9997 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O01 compound treatment 45040.0 -2380.0 -0.14 50000.0 3000.0 0.23 0.0631 0.2374 3087345 TimTec1_008405 CCc1c(C)sc(NC(=O)c2cc(on2)c3ccccc3)c1C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O02 compound treatment 50480.0 3060.0 0.18 47880.0 879.0 0.07 0.1724 0.9104 3211400 TimTec1_008406 CCOC(=O)C1CCN(CC1)C(=O)C(C(=O)c2ccccc2)n3ccccc3=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O03 compound treatment 33080.0 -14300.0 -0.83 48800.0 1800.0 0.14 -0.4912 -0.5834 1120969 TimTec1_008407 OCC(NCc1ccccc1)C#CCN2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O04 compound treatment 18560.0 -28900.0 -1.67 37440.0 -9560.0 -0.72 -1.694 -0.9298 3211401 TimTec1_008408 Clc1c(sc2ccccc12)C(=O)N(CC#N)CC#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O05 compound treatment 26360.0 -21100.0 -1.22 42320.0 -4680.0 -0.35 -1.1133 -0.8763 3087346 TimTec1_008409 Cc1cccc(c1)C(=O)OCCN2CCOCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O06 compound treatment 42760.0 -4660.0 -0.27 41280.0 -5720.0 -0.43 -0.4971 -0.9741 1523381 TimTec1_008410 NCCc1c([nH]c2ccc(Br)cc12)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O07 compound treatment 31640.0 -15800.0 -0.91 39960.0 -7040.0 -0.53 -1.0233 -0.967 3087347 TimTec1_008411 CC1CCCC(C)N1Cc2ccc(N)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O08 compound treatment 36080.0 -11300.0 -0.66 43440.0 -3560.0 -0.27 -0.6551 -0.9226 1667083 TimTec1_008412 CCOC(=O)CC1(O)CCOC(C)(C)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O09 compound treatment 30720.0 -16700.0 -0.97 40800.0 -6200.0 -0.47 -1.016 -0.9448 1350048 TimTec1_008413 OC(=O)CCCC(=O)Nc1nccs1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O10 compound treatment 19400.0 -28000.0 -1.62 30320.0 -16700.0 -1.26 -2.0407 -0.9923 3087348 TimTec1_008414 CC1=CCC(CC1)C2OCC3CC=C(C)C2C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O11 compound treatment 30000.0 -17400.0 -1.01 44800.0 -2200.0 -0.17 -0.8314 -0.8128 1227036 TimTec1_008415 C(NCc1ccco1)C2OCc3ccccc3CO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O12 compound treatment 16840.0 -30600.0 -1.77 26600.0 -20400.0 -1.54 -2.3447 -0.9977 3211402 TimTec1_008416 COc1ccc(cc1)C(CCNCc2ccccc2)C3CCOC(C)(C)C3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O13 compound treatment 34480.0 -12900.0 -0.75 39080.0 -7920.0 -0.6 -0.9541 -0.9939 1661425 TimTec1_008417 CCc1ccccc1NC(=O)CC2Nc3ccccc3NC2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O14 compound treatment 38800.0 -8620.0 -0.5 40720.0 -6280.0 -0.48 -0.6893 -0.9997 1171536 TimTec1_008418 CC(C)(C)c1ccc(CNCc2ccco2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O15 compound treatment 35040.0 -12400.0 -0.72 42880.0 -4120.0 -0.31 -0.7277 -0.9305 3211403 TimTec1_008419 Cc1ccc(cc1)N2CC(CC2=O)C(=O)NCc3ccccn3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O16 compound treatment 34800.0 -12600.0 -0.73 43360.0 -3640.0 -0.28 -0.7119 -0.9111 1064846 TimTec1_008420 COc1ccccc1CNCc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O17 compound treatment 27280.0 -20100.0 -1.17 36440.0 -10600.0 -0.8 -1.3903 -0.983 3211404 TimTec1_008421 CCN(CC)C(=O)C(C(=O)c1ccccc1)n2cc(Cl)ccc2=O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O18 compound treatment 36120.0 -11300.0 -0.65 46120.0 -881.0 -0.07 -0.5101 -0.7751 3087349 TimTec1_008422 CCOc1ccccc1CNC2CC(C)(C)NC(C)(C)C2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O19 compound treatment 37800.0 -9620.0 -0.56 36360.0 -10600.0 -0.81 -0.9636 -0.9838 3211482 TimTec1_008423 OCCN(Cc1cn[nH]c1c2ccc(F)cc2)Cc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O20 compound treatment 40280.0 -7140.0 -0.41 46840.0 -161.0 -0.01 -0.3011 -0.7277 3087350 TimTec1_008424 NCC(N1CCOCC1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O21 compound treatment 35640.0 -11800.0 -0.68 42880.0 -4120.0 -0.31 -0.7031 -0.9371 3211483 TimTec1_008425 COc1ccc(CN2CCC(CC2)C(=O)NCc3ccc(C)cc3)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O22 compound treatment 22040.0 -25400.0 -1.47 22200.0 -24800.0 -1.88 -2.3672 -0.9927 3087351 TimTec1_008426 CC(C)C1NC(Cc2c1[nH]c3ccccc23)C(=O)O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O23 mock treatment 44840.0 -2580.0 -0.15 53240.0 6240.0 0.47 0.2283 0.4609 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 O24 mock treatment 52360.0 4940.0 0.29 52160.0 5160.0 0.39 0.4786 0.9884 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P01 compound treatment 38120.0 -9300.0 -0.54 52520.0 5520.0 0.42 -0.0856 -0.1255 3211484 TimTec1_008427 CN1CCN(CC1)C(=O)C2CCC(C)(C(=O)O)C2(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P02 compound treatment 38320.0 -9100.0 -0.53 44280.0 -2720.0 -0.21 -0.5184 -0.916 1580692 TimTec1_008428 Fc1ccc(NC(=O)COc2ccc(cc2)N3CC(CC3=O)C(=O)NCC=C)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P03 compound treatment 30120.0 -17300.0 -1.0 40280.0 -6720.0 -0.51 -1.0684 -0.9506 3087352 TimTec1_008429 Nc1ccc(CN2CCCCCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P04 compound treatment 12960.0 -34500.0 -2.0 33440.0 -13600.0 -1.03 -2.1376 -0.9522 3087353 TimTec1_008430 Cc1cc(OCC(=O)Nc2nnn(C)n2)ccc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P05 compound treatment 20080.0 -27300.0 -1.58 36280.0 -10700.0 -0.81 -1.6939 -0.9517 1521332 TimTec1_008431 CC(C)C1CC(CCN)(Cc2ccccc2)CCO1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P06 compound treatment 34800.0 -12600.0 -0.73 38640.0 -8360.0 -0.63 -0.9645 -0.9974 3087354 TimTec1_008432 Cc1ccc(CC2SC(=O)NC2=O)cc1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P07 compound treatment 15360.0 -32100.0 -1.86 17160.0 -29800.0 -2.26 -2.9106 -0.9953 1530249 TimTec1_008433 Oc1ccnc2cccc(Cc3ccccc3)c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P08 compound treatment 1480.0 -45900.0 -2.66 2120.0 -44900.0 -3.4 -4.2842 -0.9927 1360748 TimTec1_008434 Cc1nc2sccn2c1c3csc(NCc4ccco4)n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P09 compound treatment 26360.0 -21100.0 -1.22 32840.0 -14200.0 -1.07 -1.6207 -0.9979 1231944 TimTec1_008435 CCOC(=O)C1C(C(C1c2ccccc2)C(=O)OCC)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P10 compound treatment 9400.0 -38000.0 -2.2 18480.0 -28500.0 -2.16 -3.0841 -0.9999 3211485 TimTec1_008436 Oc1ccc(CNc2ccc(F)cc2)c3cccnc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P11 compound treatment 25480.0 -21900.0 -1.27 28000.0 -19000.0 -1.44 -1.9158 -0.9981 1543749 TimTec1_008437 Cc1ccccc1OCC2Cn3c(O2)nc4n(C)c(=O)[nH]c(=O)c34 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P12 compound treatment 25280.0 -22100.0 -1.28 37880.0 -9120.0 -0.69 -1.3952 -0.9578 3087355 TimTec1_008438 CN1CCC(CC1)OC(=O)COc2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P13 compound treatment 9760.0 -37700.0 -2.18 12800.0 -34200.0 -2.59 -3.3734 -0.9964 1684258 TimTec1_008439 Cc1c(C)c2cc(ccc2n1Cc3ccccc3)C(=O)Nc4nc[nH]n4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P14 compound treatment 27480.0 -19900.0 -1.16 32400.0 -14600.0 -1.11 -1.5984 -0.9998 3087356 TimTec1_008440 O=C(COc1ccccc1)Nc2ccc3oc(=O)ccc3c2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P15 compound treatment 28600.0 -18800.0 -1.09 37360.0 -9640.0 -0.73 -1.287 -0.9809 1396380 TimTec1_008441 CCC(CO)NC(=O)c1ccc(N)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P16 compound treatment 24640.0 -22800.0 -1.32 36880.0 -10100.0 -0.77 -1.4749 -0.9665 3087357 TimTec1_008442 COc1ccc(cc1)n2cccc2CO 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P17 compound treatment 24640.0 -22800.0 -1.32 37640.0 -9360.0 -0.71 -1.4343 -0.9575 1269164 TimTec1_008443 CCN1CCN(CCC(=O)Nc2ccccc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P18 compound treatment 27320.0 -20100.0 -1.16 41400.0 -5600.0 -0.42 -1.1232 -0.9064 1595939 TimTec1_008444 COc1ccc(cc1)c2nn(CCC#N)cc2C#N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P19 compound treatment 29720.0 -17700.0 -1.03 38880.0 -8120.0 -0.61 -1.1598 -0.9701 1426447 TimTec1_008445 O=C(NCCN1CCOCC1)c2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P20 compound treatment 32560.0 -14900.0 -0.86 41840.0 -5160.0 -0.39 -0.885 -0.9361 3087358 TimTec1_008446 CCc1cccc2c(O)c(CN(C)C)c(C)nc12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P21 compound treatment 25720.0 -21700.0 -1.26 31720.0 -15300.0 -1.16 -1.7069 -0.9991 1501786 TimTec1_008447 Nc1cc(Cl)ccc1N2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P22 compound treatment 48320.0 901.0 0.05 38480.0 -8520.0 -0.65 -0.4192 -0.6477 1517444 TimTec1_008448 CCOC(=O)C1=C(C)NC(=O)C(C(=O)N)C21CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P23 mock treatment 39680.0 -7740.0 -0.45 43680.0 -3320.0 -0.25 -0.4948 -0.9626 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2086 P24 mock treatment 45480.0 -1940.0 -0.11 41520.0 -5480.0 -0.41 -0.3728 -0.8673 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A01 compound treatment 45640.0 -1780.0 -0.1 47960.0 1620.0 0.12 0.014 0.0875 1077351 TimTec1_008449 COC(=O)c1cncn1C(C)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A02 compound treatment 49400.0 1980.0 0.11 45960.0 -376.0 -0.03 0.061 0.516 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A03 compound treatment 20200.0 -27200.0 -1.58 16560.0 -29800.0 -2.25 -2.7088 -0.9847 3211486 TimTec1_008450 CC(=O)N1CCN(CC1)c2ccc(NC(=O)COc3cc(C)c(Cl)c(C)c3)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A04 compound treatment 47520.0 101.0 0.01 40000.0 -6340.0 -0.48 -0.335 -0.6984 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A05 compound treatment 24240.0 -23200.0 -1.34 24880.0 -21500.0 -1.62 -2.098 -0.9955 3087359 TimTec1_008451 O=c1sc2ccccc2n1CCOc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A06 compound treatment 46840.0 -579.0 -0.03 42320.0 -4020.0 -0.3 -0.2387 -0.7804 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A07 compound treatment 48920.0 1500.0 0.09 50360.0 4020.0 0.3 0.2769 0.8741 3087360 TimTec1_008452 CCCN1CCC(CC1)NCc2ccco2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A08 compound treatment 47400.0 -18.8 0.0 42040.0 -4300.0 -0.33 -0.2307 -0.7095 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A09 compound treatment 45080.0 -2340.0 -0.14 53440.0 7100.0 0.54 0.2844 0.5129 3211487 TimTec1_008453 CC(C)(C)C(=O)COC(=O)C1CN(C(=O)C1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A10 compound treatment 35560.0 -11900.0 -0.69 41800.0 -4540.0 -0.34 -0.7286 -0.9486 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A11 compound treatment 34280.0 -13100.0 -0.76 42560.0 -3780.0 -0.29 -0.7404 -0.9105 3087361 TimTec1_008454 Cc1ccc(cc1)c2ccc(C(=O)O)n2C=C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A12 compound treatment 42000.0 -5420.0 -0.31 41920.0 -4420.0 -0.33 -0.4584 -0.9995 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A13 compound treatment 10960.0 -36500.0 -2.11 11680.0 -34700.0 -2.62 -3.3486 -0.9942 1686575 TimTec1_008455 CCN(CC)CCC(=O)c1ccc(F)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A14 compound treatment 36000.0 -11400.0 -0.66 42760.0 -3580.0 -0.27 -0.6592 -0.9222 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A15 compound treatment 34440.0 -13000.0 -0.75 35480.0 -10900.0 -0.82 -1.1128 -0.999 3211488 TimTec1_008456 O=C(CSc1ccccn1)N2CCN(CC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A16 compound treatment 41200.0 -6220.0 -0.36 41760.0 -4580.0 -0.35 -0.4997 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A17 compound treatment 32440.0 -15000.0 -0.87 32480.0 -13900.0 -1.05 -1.3553 -0.9956 3087362 TimTec1_008457 Clc1ncn(CCOc2ccccc2)c1Cl 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A18 compound treatment 40760.0 -6660.0 -0.39 43840.0 -2500.0 -0.19 -0.4064 -0.9461 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A19 compound treatment 44480.0 -2940.0 -0.17 43440.0 -2900.0 -0.22 -0.2754 -0.9922 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A20 compound treatment 50400.0 2980.0 0.17 45520.0 -816.0 -0.06 0.0784 0.4276 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A21 compound treatment 44160.0 -3260.0 -0.19 42560.0 -3780.0 -0.29 -0.3356 -0.9797 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A22 compound treatment 46040.0 -1380.0 -0.08 43000.0 -3340.0 -0.25 -0.2351 -0.8874 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A23 mock treatment 53080.0 5660.0 0.33 50880.0 4540.0 0.34 0.4751 0.9997 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 A24 mock treatment 54600.0 7180.0 0.42 59320.0 13000.0 0.98 0.9891 0.9268 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B01 compound treatment 54920.0 7500.0 0.43 51480.0 5140.0 0.39 0.5826 0.9985 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B02 compound treatment 58160.0 10700.0 0.62 50840.0 4500.0 0.34 0.6811 0.9599 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B03 compound treatment 55280.0 7860.0 0.46 51960.0 5620.0 0.43 0.6231 0.9994 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B04 compound treatment 54520.0 7100.0 0.41 45120.0 -1220.0 -0.09 0.2258 0.5356 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B05 compound treatment 44720.0 -2700.0 -0.16 40240.0 -6100.0 -0.46 -0.4369 -0.8966 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B06 compound treatment 55880.0 8460.0 0.49 35040.0 -11300.0 -0.86 -0.258 -0.2617 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B07 compound treatment 44680.0 -2740.0 -0.16 40320.0 -6020.0 -0.46 -0.4342 -0.9004 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B08 compound treatment 42160.0 -5260.0 -0.3 36480.0 -9860.0 -0.75 -0.743 -0.922 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B09 compound treatment 42240.0 -5180.0 -0.3 37480.0 -8860.0 -0.67 -0.6862 -0.9343 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B10 compound treatment 36440.0 -11000.0 -0.64 37560.0 -8780.0 -0.66 -0.9195 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B11 compound treatment 39880.0 -7540.0 -0.44 39560.0 -6780.0 -0.51 -0.6715 -0.9968 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B12 compound treatment 46080.0 -1340.0 -0.08 42240.0 -4100.0 -0.31 -0.2741 -0.8576 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B13 compound treatment 38520.0 -8900.0 -0.52 39320.0 -7020.0 -0.53 -0.7401 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B14 compound treatment 42480.0 -4940.0 -0.29 39080.0 -7260.0 -0.55 -0.5907 -0.9538 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B15 compound treatment 41320.0 -6100.0 -0.35 41520.0 -4820.0 -0.36 -0.5076 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B16 compound treatment 44560.0 -2860.0 -0.17 39440.0 -6900.0 -0.52 -0.4862 -0.8878 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B17 compound treatment 44680.0 -2740.0 -0.16 39920.0 -6420.0 -0.49 -0.4556 -0.8917 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B18 compound treatment 40440.0 -6980.0 -0.4 40520.0 -5820.0 -0.44 -0.5972 -0.9991 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B19 compound treatment 45840.0 -1580.0 -0.09 41160.0 -5180.0 -0.39 -0.3417 -0.8493 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B20 compound treatment 49120.0 1700.0 0.1 46560.0 224.0 0.02 0.0817 0.8166 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B21 compound treatment 44040.0 -3380.0 -0.2 50480.0 4140.0 0.31 0.0834 0.2255 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B22 compound treatment 51760.0 4340.0 0.25 48080.0 1740.0 0.13 0.2712 0.9547 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B23 mock treatment 59640.0 12200.0 0.71 54920.0 8580.0 0.65 0.9601 0.9991 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 B24 mock treatment 51720.0 4300.0 0.25 58320.0 12000.0 0.91 0.8176 0.8692 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C01 compound treatment 10800.0 -36600.0 -2.12 15520.0 -30800.0 -2.33 -3.1496 -0.9989 3211489 TimTec1_008458 OC(c1ccc([nH]1)c2ccccc2)C(F)(F)F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C02 compound treatment 46960.0 -459.0 -0.03 49240.0 2900.0 0.22 0.1366 0.6171 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C03 compound treatment 24480.0 -22900.0 -1.33 25280.0 -21100.0 -1.59 -2.0668 -0.9959 3087363 TimTec1_008459 NCCCn1c2CCCCc2c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C04 compound treatment 46520.0 -899.0 -0.05 40160.0 -6180.0 -0.47 -0.3674 -0.781 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C05 compound treatment 10600.0 -36800.0 -2.13 9160.0 -37200.0 -2.81 -3.4982 -0.9907 3211490 TimTec1_008460 Cc1cc(C)c(C#N)c(n1)N2C3CCC2CC(O)(C3)c4ccc(F)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C06 compound treatment 40640.0 -6780.0 -0.39 42640.0 -3700.0 -0.28 -0.4756 -0.9862 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C07 compound treatment 48760.0 1340.0 0.08 45720.0 -616.0 -0.05 0.022 0.2423 3087364 TimTec1_008461 Cc1ccccc1CN2CCC(CC2)N3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C08 compound treatment 43320.0 -4100.0 -0.24 39760.0 -6580.0 -0.5 -0.5199 -0.9427 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C09 compound treatment 29600.0 -17800.0 -1.03 32360.0 -14000.0 -1.06 -1.4781 -0.9999 3211491 TimTec1_008462 FC(F)(F)c1ccc(NCc2cn3ccccc3n2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C10 compound treatment 41200.0 -6220.0 -0.36 38600.0 -7740.0 -0.59 -0.6688 -0.9728 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C11 compound treatment 43520.0 -3900.0 -0.23 38600.0 -7740.0 -0.59 -0.5738 -0.9142 1349387 TimTec1_008463 COc1ccc2n(C)c(C)c(c3csc(N)n3)c2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C12 compound treatment 43880.0 -3540.0 -0.21 37640.0 -8700.0 -0.66 -0.6104 -0.8854 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C13 compound treatment 42400.0 -5020.0 -0.29 44040.0 -2300.0 -0.17 -0.3285 -0.9697 3211492 TimTec1_008464 Oc1ccc(cc1)C(=O)OCCCN2CCCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C14 compound treatment 42360.0 -5060.0 -0.29 38400.0 -7940.0 -0.6 -0.632 -0.9456 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C15 compound treatment 24840.0 -22600.0 -1.31 24400.0 -21900.0 -1.66 -2.0991 -0.993 3211493 TimTec1_008465 COc1cccc(Cn2c(nc3ccccc23)c4cncs4)c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C16 compound treatment 41000.0 -6420.0 -0.37 33800.0 -12500.0 -0.95 -0.934 -0.9164 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C17 compound treatment 38120.0 -9300.0 -0.54 36760.0 -9580.0 -0.72 -0.8935 -0.9893 3087365 TimTec1_008466 Cc1ccccc1OCCCn2cnc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C18 compound treatment 43720.0 -3700.0 -0.21 38560.0 -7780.0 -0.59 -0.5677 -0.9063 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C19 compound treatment 42520.0 -4900.0 -0.28 40680.0 -5660.0 -0.43 -0.5034 -0.9801 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C20 compound treatment 45640.0 -1780.0 -0.1 39320.0 -7020.0 -0.53 -0.4484 -0.8289 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C21 compound treatment 49320.0 1900.0 0.11 38360.0 -7980.0 -0.6 -0.349 -0.5687 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C22 compound treatment 41160.0 -6260.0 -0.36 46240.0 -96.3 -0.01 -0.2616 -0.7212 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C23 mock treatment 52840.0 5420.0 0.31 52320.0 5980.0 0.45 0.5424 0.984 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 C24 mock treatment 53760.0 6340.0 0.37 50440.0 4100.0 0.31 0.4794 0.9965 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D01 compound treatment 41960.0 -5460.0 -0.32 45080.0 -1260.0 -0.1 -0.2909 -0.8808 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D02 compound treatment 47480.0 61.3 0.0 37720.0 -8620.0 -0.65 -0.4587 -0.7032 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D03 compound treatment 45920.0 -1500.0 -0.09 42160.0 -4180.0 -0.32 -0.2849 -0.8691 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D04 compound treatment 45080.0 -2340.0 -0.14 39560.0 -6780.0 -0.51 -0.4585 -0.8643 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D05 compound treatment 42440.0 -4980.0 -0.29 36400.0 -9940.0 -0.75 -0.7358 -0.9134 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D06 compound treatment 43160.0 -4260.0 -0.25 37600.0 -8740.0 -0.66 -0.6421 -0.9097 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D07 compound treatment 38480.0 -8940.0 -0.52 37440.0 -8900.0 -0.67 -0.8424 -0.9916 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D08 compound treatment 42000.0 -5420.0 -0.31 38040.0 -8300.0 -0.63 -0.666 -0.9487 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D09 compound treatment 42840.0 -4580.0 -0.27 39800.0 -6540.0 -0.49 -0.5374 -0.9573 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D10 compound treatment 38200.0 -9220.0 -0.53 40920.0 -5420.0 -0.41 -0.6676 -0.9915 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D11 compound treatment 39560.0 -7860.0 -0.46 40080.0 -6260.0 -0.47 -0.6568 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D12 compound treatment 38760.0 -8660.0 -0.5 36040.0 -10300.0 -0.78 -0.9058 -0.9773 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D13 compound treatment 39720.0 -7700.0 -0.45 31240.0 -15100.0 -1.14 -1.1234 -0.9158 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D14 compound treatment 33680.0 -13700.0 -0.8 34120.0 -12200.0 -0.92 -1.2167 -0.9972 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D15 compound treatment 35920.0 -11500.0 -0.67 36200.0 -10100.0 -0.77 -1.0136 -0.9975 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D16 compound treatment 38640.0 -8780.0 -0.51 39240.0 -7100.0 -0.54 -0.7395 -0.9996 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D17 compound treatment 39520.0 -7900.0 -0.46 38280.0 -8060.0 -0.61 -0.7548 -0.99 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D18 compound treatment 43000.0 -4420.0 -0.26 36840.0 -9500.0 -0.72 -0.6893 -0.9034 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D19 compound treatment 44720.0 -2700.0 -0.16 36800.0 -9540.0 -0.72 -0.621 -0.8408 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D20 compound treatment 46160.0 -1260.0 -0.07 40960.0 -5380.0 -0.41 -0.3393 -0.8208 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D21 compound treatment 49440.0 2020.0 0.12 40360.0 -5980.0 -0.45 -0.2371 -0.5073 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D22 compound treatment 48520.0 1100.0 0.06 41640.0 -4700.0 -0.36 -0.2062 -0.5711 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D23 mock treatment 52280.0 4860.0 0.28 54280.0 7940.0 0.6 0.6243 0.9403 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 D24 mock treatment 52160.0 4740.0 0.27 48400.0 2060.0 0.16 0.3047 0.9642 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E01 compound treatment 19120.0 -28300.0 -1.64 18800.0 -27500.0 -2.08 -2.6332 -0.9929 1720370 TimTec1_008467 C1CCC(CC1)Nc2nnnn2c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E02 compound treatment 39640.0 -7780.0 -0.45 43120.0 -3220.0 -0.24 -0.4908 -0.9582 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E03 compound treatment 49840.0 2420.0 0.14 43160.0 -3180.0 -0.24 -0.0708 -0.2544 3087366 TimTec1_008468 CCC(=O)Nc1ccc(cc1)N2CCN(CC2)C(=O)C(C)C 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E04 compound treatment 43280.0 -4140.0 -0.24 39960.0 -6380.0 -0.48 -0.5108 -0.9479 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E05 compound treatment 3960.0 -43500.0 -2.52 4000.0 -42300.0 -3.2 -4.0464 -0.9929 3211494 TimTec1_008469 Oc1nc2nonc2nc1Nc3ccccc3F 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E06 compound treatment 38560.0 -8860.0 -0.51 38400.0 -7940.0 -0.6 -0.7877 -0.9969 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E07 compound treatment 46120.0 -1300.0 -0.08 44880.0 -1460.0 -0.11 -0.1312 -0.9827 3087367 TimTec1_008470 Clc1cccc(c1)C(=O)N2CCNCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E08 compound treatment 41160.0 -6260.0 -0.36 43240.0 -3100.0 -0.23 -0.4221 -0.9777 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E09 compound treatment 5560.0 -41900.0 -2.43 13600.0 -32700.0 -2.48 -3.467 -0.9999 3211495 TimTec1_008471 CC/1=C(C#N)c2nc(N)c(C#N)c(C)c2\C1=C/c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E10 compound treatment 40800.0 -6620.0 -0.38 42000.0 -4340.0 -0.33 -0.5033 -0.997 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E11 compound treatment 38120.0 -9300.0 -0.54 37280.0 -9060.0 -0.69 -0.8657 -0.9929 1406058 TimTec1_008472 OC(=O)CCNc1nc2ccccc2s1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E12 compound treatment 34200.0 -13200.0 -0.77 40720.0 -5620.0 -0.43 -0.8422 -0.9614 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E13 compound treatment 34480.0 -12900.0 -0.75 37520.0 -8820.0 -0.67 -1.002 -0.9983 1411493 TimTec1_008473 CC(C)(C)c1cn2c(nc3ccccc32)n1CCCO 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E14 compound treatment 34840.0 -12600.0 -0.73 35360.0 -11000.0 -0.83 -1.1028 -0.9979 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E15 compound treatment 39040.0 -8380.0 -0.49 39960.0 -6380.0 -0.48 -0.6845 -1.0 1197110 TimTec1_008474 OC1(CCCCC1)C#CCN2CCN(CC2)C(=O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E16 compound treatment 33400.0 -14000.0 -0.81 36880.0 -9460.0 -0.72 -1.0805 -0.998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E17 compound treatment 8400.0 -39000.0 -2.26 11600.0 -34700.0 -2.63 -3.4577 -0.9972 3087413 TimTec1_008475 COc1nc(N)c(C#N)c(c1C#N)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E18 compound treatment 41560.0 -5860.0 -0.34 41240.0 -5100.0 -0.39 -0.5128 -0.998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E19 compound treatment 40080.0 -7340.0 -0.43 33720.0 -12600.0 -0.95 -0.9759 -0.9336 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E20 compound treatment 37400.0 -10000.0 -0.58 40000.0 -6340.0 -0.48 -0.7496 -0.9955 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E21 compound treatment 40480.0 -6940.0 -0.4 39360.0 -6980.0 -0.53 -0.6577 -0.9909 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E22 compound treatment 47360.0 -58.8 0.0 42480.0 -3860.0 -0.29 -0.2088 -0.7153 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E23 mock treatment 48520.0 1100.0 0.06 45560.0 -776.0 -0.06 0.0036 0.0411 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 E24 mock treatment 49880.0 2460.0 0.14 48240.0 1900.0 0.14 0.2027 1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F01 compound treatment 39000.0 -8420.0 -0.49 47680.0 1340.0 0.1 -0.273 -0.5479 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F02 compound treatment 42240.0 -5180.0 -0.3 43840.0 -2500.0 -0.19 -0.3458 -0.9752 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F03 compound treatment 45640.0 -1780.0 -0.1 37040.0 -9300.0 -0.7 -0.5704 -0.8021 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F04 compound treatment 42760.0 -4660.0 -0.27 37840.0 -8500.0 -0.64 -0.6456 -0.9257 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F05 compound treatment 40440.0 -6980.0 -0.4 49400.0 3060.0 0.23 -0.1219 -0.2616 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F06 compound treatment 40360.0 -7060.0 -0.41 43760.0 -2580.0 -0.2 -0.4271 -0.9426 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F07 compound treatment 42320.0 -5100.0 -0.3 38680.0 -7660.0 -0.58 -0.6187 -0.9511 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F08 compound treatment 42480.0 -4940.0 -0.29 45800.0 -536.0 -0.04 -0.231 -0.7994 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F09 compound treatment 39040.0 -8380.0 -0.49 36640.0 -9700.0 -0.73 -0.8622 -0.9799 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F10 compound treatment 41440.0 -5980.0 -0.35 44960.0 -1380.0 -0.1 -0.3186 -0.8808 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F11 compound treatment 39960.0 -7460.0 -0.43 40600.0 -5740.0 -0.43 -0.6126 -1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F12 compound treatment 37800.0 -9620.0 -0.56 42720.0 -3620.0 -0.27 -0.5876 -0.9464 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F13 compound treatment 43600.0 -3820.0 -0.22 39240.0 -7100.0 -0.54 -0.5363 -0.9231 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F14 compound treatment 34280.0 -13100.0 -0.76 45240.0 -1100.0 -0.08 -0.5969 -0.7796 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F15 compound treatment 35640.0 -11800.0 -0.68 36320.0 -10000.0 -0.76 -1.0187 -0.9986 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F16 compound treatment 37640.0 -9780.0 -0.57 37480.0 -8860.0 -0.67 -0.8746 -0.9965 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F17 compound treatment 36000.0 -11400.0 -0.66 37040.0 -9300.0 -0.7 -0.9654 -0.9995 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F18 compound treatment 40880.0 -6540.0 -0.38 37480.0 -8860.0 -0.67 -0.7419 -0.9635 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F19 compound treatment 40200.0 -7220.0 -0.42 40120.0 -6220.0 -0.47 -0.6285 -0.9983 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F20 compound treatment 43520.0 -3900.0 -0.23 44680.0 -1660.0 -0.13 -0.2484 -0.9614 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F21 compound treatment 40520.0 -6900.0 -0.4 38680.0 -7660.0 -0.58 -0.6924 -0.9836 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F22 compound treatment 42520.0 -4900.0 -0.28 42120.0 -4220.0 -0.32 -0.4264 -0.9983 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F23 mock treatment 45120.0 -2300.0 -0.13 46320.0 -16.3 0.0 -0.095 -0.7136 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 F24 mock treatment 48040.0 621.0 0.04 46200.0 -136.0 -0.01 0.0182 0.485 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G01 compound treatment 30600.0 -16800.0 -0.97 31000.0 -15300.0 -1.16 -1.5099 -0.9962 1325717 TimTec1_008476 OC(COc1ccccc1)Cn2cnc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G02 compound treatment 42000.0 -5420.0 -0.31 39520.0 -6820.0 -0.52 -0.5868 -0.9716 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G03 compound treatment 40840.0 -6580.0 -0.38 40800.0 -5540.0 -0.42 -0.5658 -0.9989 1168629 TimTec1_008477 Nc1nonc1C(=O)OCC(=O)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G04 compound treatment 34360.0 -13100.0 -0.76 36400.0 -9940.0 -0.75 -1.0668 -1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G05 compound treatment 42480.0 -4940.0 -0.29 40280.0 -6060.0 -0.46 -0.5265 -0.9743 1787057 TimTec1_008478 CC(=O)OC1CN2CCC1C(C2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G06 compound treatment 34040.0 -13400.0 -0.78 38280.0 -8060.0 -0.61 -0.9793 -0.993 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G07 compound treatment 43040.0 -4380.0 -0.25 40360.0 -5980.0 -0.45 -0.4993 -0.9626 3087414 TimTec1_008479 CN1CCCC(C1)OC(=O)COc2ccc(C)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G08 compound treatment 39880.0 -7540.0 -0.44 40160.0 -6180.0 -0.47 -0.6394 -0.9994 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G09 compound treatment 44200.0 -3220.0 -0.19 41640.0 -4700.0 -0.36 -0.3832 -0.9547 1134052 TimTec1_008480 CC(C)(C)N1CC(CO)OC1c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G10 compound treatment 38600.0 -8820.0 -0.51 37920.0 -8420.0 -0.64 -0.8118 -0.994 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G11 compound treatment 36680.0 -10700.0 -0.62 38360.0 -7980.0 -0.6 -0.8669 -0.9999 3087415 TimTec1_008481 CCN1CCN(Cc2ccc(N)cc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G12 compound treatment 31680.0 -15700.0 -0.91 39320.0 -7020.0 -0.53 -1.0203 -0.9669 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G13 compound treatment 19320.0 -28100.0 -1.63 21160.0 -25200.0 -1.91 -2.4987 -0.9969 1650768 TimTec1_008482 O=C(Nc1ccncc1)C2(CCCC2)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G14 compound treatment 36440.0 -11000.0 -0.64 42680.0 -3660.0 -0.28 -0.6455 -0.9305 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G15 compound treatment 3680.0 -43700.0 -2.53 5320.0 -41000.0 -3.1 -3.9872 -0.9949 3211571 TimTec1_008483 Cc1ccc(cc1C)c2[nH]ncc2CNCc3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G16 compound treatment 35880.0 -11500.0 -0.67 40720.0 -5620.0 -0.43 -0.7733 -0.9761 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G17 compound treatment 35200.0 -12200.0 -0.71 32320.0 -14000.0 -1.06 -1.2508 -0.9807 3087416 TimTec1_008484 COC(=O)c1cc([nH]n1)c2ccccc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G18 compound treatment 35440.0 -12000.0 -0.69 33360.0 -13000.0 -0.98 -1.1853 -0.9855 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G19 compound treatment 43280.0 -4140.0 -0.24 42960.0 -3380.0 -0.26 -0.3503 -0.9995 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G20 compound treatment 36320.0 -11100.0 -0.64 41840.0 -4500.0 -0.34 -0.6954 -0.9557 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G21 compound treatment 37960.0 -9460.0 -0.55 38880.0 -7460.0 -0.56 -0.7866 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G22 compound treatment 34520.0 -12900.0 -0.75 37840.0 -8500.0 -0.64 -0.9832 -0.9972 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G23 mock treatment 45280.0 -2140.0 -0.12 42920.0 -3420.0 -0.26 -0.2705 -0.9432 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 G24 mock treatment 46200.0 -1220.0 -0.07 46320.0 -16.3 0.0 -0.0508 -0.7193 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H01 compound treatment 45600.0 -1820.0 -0.11 44320.0 -2020.0 -0.15 -0.1824 -0.9836 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H02 compound treatment 41440.0 -5980.0 -0.35 41360.0 -4980.0 -0.38 -0.5113 -0.9991 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H03 compound treatment 41200.0 -6220.0 -0.36 37760.0 -8580.0 -0.65 -0.7138 -0.9614 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H04 compound treatment 42800.0 -4620.0 -0.27 36080.0 -10300.0 -0.78 -0.7382 -0.8989 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H05 compound treatment 45280.0 -2140.0 -0.12 39800.0 -6540.0 -0.49 -0.4375 -0.8577 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H06 compound treatment 39520.0 -7900.0 -0.46 36840.0 -9500.0 -0.72 -0.8319 -0.9762 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H07 compound treatment 40320.0 -7100.0 -0.41 34120.0 -12200.0 -0.92 -0.9447 -0.9334 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H08 compound treatment 41360.0 -6060.0 -0.35 39120.0 -7220.0 -0.55 -0.6345 -0.9771 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H09 compound treatment 39960.0 -7460.0 -0.43 39640.0 -6700.0 -0.51 -0.664 -0.9968 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H10 compound treatment 33320.0 -14100.0 -0.82 39800.0 -6540.0 -0.49 -0.9274 -0.9711 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H11 compound treatment 33120.0 -14300.0 -0.83 38600.0 -7740.0 -0.59 -0.9999 -0.9856 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H12 compound treatment 36640.0 -10800.0 -0.62 39360.0 -6980.0 -0.53 -0.815 -0.9965 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H13 compound treatment 33640.0 -13800.0 -0.8 36960.0 -9380.0 -0.71 -1.0663 -0.9983 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H14 compound treatment 33560.0 -13900.0 -0.8 42120.0 -4220.0 -0.32 -0.7934 -0.9183 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H15 compound treatment 42800.0 -4620.0 -0.27 39560.0 -6780.0 -0.51 -0.5519 -0.954 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H16 compound treatment 39120.0 -8300.0 -0.48 43560.0 -2780.0 -0.21 -0.4886 -0.9311 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H17 compound treatment 34200.0 -13200.0 -0.77 40120.0 -6220.0 -0.47 -0.8743 -0.9726 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H18 compound treatment 35640.0 -11800.0 -0.68 41360.0 -4980.0 -0.38 -0.7489 -0.9608 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H19 compound treatment 39280.0 -8140.0 -0.47 43520.0 -2820.0 -0.21 -0.4842 -0.9356 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H20 compound treatment 39120.0 -8300.0 -0.48 39720.0 -6620.0 -0.5 -0.6941 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H21 compound treatment 43480.0 -3940.0 -0.23 39000.0 -7340.0 -0.56 -0.554 -0.9228 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H22 compound treatment 41160.0 -6260.0 -0.36 38720.0 -7620.0 -0.58 -0.6641 -0.975 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H23 mock treatment 52360.0 4940.0 0.29 42440.0 -3900.0 -0.29 -0.0061 -0.0149 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 H24 mock treatment 42480.0 -4940.0 -0.29 45280.0 -1060.0 -0.08 -0.2589 -0.8713 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I01 compound treatment 29800.0 -17600.0 -1.02 30800.0 -15500.0 -1.18 -1.5534 -0.9975 3211572 TimTec1_008485 CC(=O)OC(COc1ccccc1)Cn2cnc3ccccc23 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I02 compound treatment 40000.0 -7420.0 -0.43 41600.0 -4740.0 -0.36 -0.5574 -0.9959 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I03 compound treatment 37280.0 -10100.0 -0.59 45520.0 -816.0 -0.06 -0.4591 -0.7772 3087417 TimTec1_008486 COc1ccc(cc1Br)C(=O)COC(=O)CCc2nc3ccccc3nc2O 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I04 compound treatment 44800.0 -2620.0 -0.15 35200.0 -11100.0 -0.84 -0.7033 -0.8212 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I05 compound treatment 41760.0 -5660.0 -0.33 43320.0 -3020.0 -0.23 -0.3933 -0.9844 3211573 TimTec1_008487 Cc1ccc(cc1)C(=O)NCCN2CCCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I06 compound treatment 37000.0 -10400.0 -0.6 36000.0 -10300.0 -0.78 -0.9801 -0.9918 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I07 compound treatment 38200.0 -9220.0 -0.53 33640.0 -12700.0 -0.96 -1.0572 -0.9616 3211574 TimTec1_008488 Cc1ccc(OCCCC(=O)Nc2nccs2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I08 compound treatment 33320.0 -14100.0 -0.82 37400.0 -8940.0 -0.68 -1.0559 -0.9956 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I09 compound treatment 40440.0 -6980.0 -0.4 42280.0 -4060.0 -0.31 -0.503 -0.9908 3087418 TimTec1_008489 N#CC1CCN(Cc2ccccc2)CC1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I10 compound treatment 37960.0 -9460.0 -0.55 38840.0 -7500.0 -0.57 -0.7887 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I11 compound treatment 15520.0 -31900.0 -1.85 16680.0 -29700.0 -2.24 -2.8942 -0.9953 1290823 TimTec1_008490 CC(C)C(=O)N1C(C)CC(N(C(=O)C)c2ccccc2)c3ccccc13 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I12 compound treatment 35640.0 -11800.0 -0.68 38680.0 -7660.0 -0.58 -0.8923 -0.9967 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I13 compound treatment 36680.0 -10700.0 -0.62 36120.0 -10200.0 -0.77 -0.9868 -0.9942 3087419 TimTec1_008491 CCCOc1ccc(Cc2nc(N)c(NC(=O)C)c(O)n2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I14 compound treatment 34680.0 -12700.0 -0.74 40800.0 -5540.0 -0.42 -0.8182 -0.964 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I15 compound treatment 2160.0 -45300.0 -2.62 2760.0 -43600.0 -3.3 -4.1865 -0.9935 1691184 TimTec1_008492 O=c1oc2ccccc2cc1c3cn4ccccc4n3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I16 compound treatment 36720.0 -10700.0 -0.62 37120.0 -9220.0 -0.7 -0.9316 -0.9983 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I17 compound treatment 51320.0 3900.0 0.23 46840.0 504.0 0.04 0.1868 0.8149 1132623 TimTec1_008493 Cn1c2nc(c(CCC(=O)O)n2c3ccccc13)c4ccccc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I18 compound treatment 41720.0 -5700.0 -0.33 38200.0 -8140.0 -0.62 -0.669 -0.9573 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I19 compound treatment 40960.0 -6460.0 -0.37 41200.0 -5140.0 -0.39 -0.5395 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I20 compound treatment 41400.0 -6020.0 -0.35 41840.0 -4500.0 -0.34 -0.4872 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I21 compound treatment 44320.0 -3100.0 -0.18 43520.0 -2820.0 -0.21 -0.2777 -0.9964 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I22 compound treatment 39400.0 -8020.0 -0.46 41400.0 -4940.0 -0.37 -0.5927 -0.9942 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I23 mock treatment 50200.0 2780.0 0.16 42440.0 -3900.0 -0.29 -0.0946 -0.2815 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 I24 mock treatment 45200.0 -2220.0 -0.13 45520.0 -816.0 -0.06 -0.1346 -0.9436 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J01 compound treatment 42480.0 -4940.0 -0.29 41320.0 -5020.0 -0.38 -0.4708 -0.9903 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J02 compound treatment 39840.0 -7580.0 -0.44 35800.0 -10500.0 -0.8 -0.8744 -0.9605 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J03 compound treatment 41360.0 -6060.0 -0.35 37960.0 -8380.0 -0.63 -0.6965 -0.9611 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J04 compound treatment 45240.0 -2180.0 -0.13 41440.0 -4900.0 -0.37 -0.3513 -0.8973 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J05 compound treatment 33080.0 -14300.0 -0.83 38640.0 -7700.0 -0.58 -0.9994 -0.9849 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J06 compound treatment 36800.0 -10600.0 -0.62 40440.0 -5900.0 -0.45 -0.7506 -0.9876 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J07 compound treatment 36920.0 -10500.0 -0.61 37960.0 -8380.0 -0.63 -0.8784 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J08 compound treatment 39480.0 -7940.0 -0.46 38360.0 -7980.0 -0.6 -0.7522 -0.991 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J09 compound treatment 35000.0 -12400.0 -0.72 44640.0 -1700.0 -0.13 -0.5996 -0.8203 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J10 compound treatment 32800.0 -14600.0 -0.85 41200.0 -5140.0 -0.39 -0.8738 -0.9376 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J11 compound treatment 31720.0 -15700.0 -0.91 35120.0 -11200.0 -0.85 -1.2435 -0.9994 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J12 compound treatment 34400.0 -13000.0 -0.75 35120.0 -11200.0 -0.85 -1.1337 -0.9983 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J13 compound treatment 29160.0 -18300.0 -1.06 45000.0 -1340.0 -0.1 -0.8195 -0.7712 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J14 compound treatment 44000.0 -3420.0 -0.2 36880.0 -9460.0 -0.72 -0.6462 -0.8701 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J15 compound treatment 39400.0 -8020.0 -0.46 47240.0 904.0 0.07 -0.2801 -0.5966 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J16 compound treatment 36600.0 -10800.0 -0.63 42400.0 -3940.0 -0.3 -0.6539 -0.9422 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J17 compound treatment 43880.0 -3540.0 -0.21 41640.0 -4700.0 -0.36 -0.3963 -0.9658 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J18 compound treatment 40320.0 -7100.0 -0.41 38840.0 -7500.0 -0.57 -0.6921 -0.9875 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J19 compound treatment 40240.0 -7180.0 -0.42 42880.0 -3460.0 -0.26 -0.4791 -0.975 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J20 compound treatment 42240.0 -5180.0 -0.3 45080.0 -1260.0 -0.1 -0.2794 -0.8877 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J21 compound treatment 35840.0 -11600.0 -0.67 38000.0 -8340.0 -0.63 -0.9205 -0.9995 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J22 compound treatment 42760.0 -4660.0 -0.27 44760.0 -1580.0 -0.12 -0.2752 -0.9326 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J23 mock treatment 44120.0 -3300.0 -0.19 43720.0 -2620.0 -0.2 -0.2752 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 J24 mock treatment 46760.0 -659.0 -0.04 46480.0 144.0 0.01 -0.0193 -0.4861 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K01 compound treatment 39440.0 -7980.0 -0.46 39920.0 -6420.0 -0.49 -0.6703 -0.9997 1586834 TimTec1_008494 Cc1c(C#N)c2ccccc2n1CC(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K02 compound treatment 34720.0 -12700.0 -0.74 33920.0 -12400.0 -0.94 -1.1848 -0.9927 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K03 compound treatment 32640.0 -14800.0 -0.86 37000.0 -9340.0 -0.71 -1.1052 -0.9955 3211575 TimTec1_008495 CC(C)(Oc1ccc(Cl)cc1)C(=O)NCC2CCCO2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K04 compound treatment 29800.0 -17600.0 -1.02 30640.0 -15700.0 -1.19 -1.5619 -0.9971 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K05 compound treatment 29520.0 -17900.0 -1.04 32440.0 -13900.0 -1.05 -1.4771 -1.0 3087420 TimTec1_008496 NC(=O)c1ccc(CN2CCOCC2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K06 compound treatment 32720.0 -14700.0 -0.85 29360.0 -17000.0 -1.29 -1.5108 -0.98 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K07 compound treatment 38840.0 -8580.0 -0.5 36480.0 -9860.0 -0.75 -0.879 -0.9805 1260773 TimTec1_008497 Nc1c(c2nc3ccccc3s2)c4nc(C#N)c(C#N)nc4n1CC5CCCO5 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K08 compound treatment 29640.0 -17800.0 -1.03 38240.0 -8100.0 -0.61 -1.1617 -0.9692 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K09 compound treatment 32440.0 -15000.0 -0.87 34000.0 -12300.0 -0.93 -1.2739 -0.9993 3087421 TimTec1_008498 CC1CCCN(C1)C(=O)Cc2cccs2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K10 compound treatment 28440.0 -19000.0 -1.1 33800.0 -12500.0 -0.95 -1.4485 -0.9973 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K11 compound treatment 31760.0 -15700.0 -0.91 31520.0 -14800.0 -1.12 -1.4345 -0.9945 3211576 TimTec1_008499 CC1(C)CC(=O)C=C(C1)Nc2sc3CCCCc3c2C(=O)N 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K12 compound treatment 32560.0 -14900.0 -0.86 35520.0 -10800.0 -0.82 -1.1877 -0.9997 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K13 compound treatment 26480.0 -20900.0 -1.21 27400.0 -18900.0 -1.43 -1.8714 -0.9966 3087422 TimTec1_008500 Cn1c(nc2cc(N)ccc12)c3ccc4nc(N)sc4c3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K14 compound treatment 31160.0 -16300.0 -0.94 34160.0 -12200.0 -0.92 -1.3178 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K15 compound treatment 31560.0 -15900.0 -0.92 32800.0 -13500.0 -1.02 -1.3742 -0.9985 1350314 TimTec1_008501 CC(C)NCCn1c(cn2c1nc3ccccc32)c4ccc(Br)cc4 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K16 compound treatment 37880.0 -9540.0 -0.55 35360.0 -11000.0 -0.83 -0.9783 -0.9804 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K17 compound treatment 31160.0 -16300.0 -0.94 31920.0 -14400.0 -1.09 -1.4377 -0.9973 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K18 compound treatment 35520.0 -11900.0 -0.69 35400.0 -10900.0 -0.83 -1.0728 -0.9959 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K19 compound treatment 31640.0 -15800.0 -0.91 36080.0 -10300.0 -0.78 -1.1954 -0.9967 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K20 compound treatment 31240.0 -16200.0 -0.94 37800.0 -8540.0 -0.65 -1.1197 -0.9835 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K21 compound treatment 32840.0 -14600.0 -0.84 28440.0 -17900.0 -1.35 -1.5551 -0.9742 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K22 compound treatment 34680.0 -12700.0 -0.74 37000.0 -9340.0 -0.71 -1.0216 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K23 mock treatment 37480.0 -9940.0 -0.58 40640.0 -5700.0 -0.43 -0.7121 -0.9898 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 K24 mock treatment 38240.0 -9180.0 -0.53 33680.0 -12700.0 -0.96 -1.0534 -0.9614 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L01 compound treatment 37120.0 -10300.0 -0.6 39240.0 -7100.0 -0.54 -0.8017 -0.9986 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L02 compound treatment 40880.0 -6540.0 -0.38 43160.0 -3180.0 -0.24 -0.4379 -0.9759 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L03 compound treatment 41400.0 -6020.0 -0.35 41800.0 -4540.0 -0.34 -0.4894 -1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L04 compound treatment 36120.0 -11300.0 -0.65 35120.0 -11200.0 -0.85 -1.0632 -0.9917 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L05 compound treatment 33480.0 -13900.0 -0.81 36400.0 -9940.0 -0.75 -1.1029 -0.9994 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L06 compound treatment 40120.0 -7300.0 -0.42 40240.0 -6100.0 -0.46 -0.6253 -0.999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L07 compound treatment 40080.0 -7340.0 -0.43 38960.0 -7380.0 -0.56 -0.6955 -0.991 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L08 compound treatment 40640.0 -6780.0 -0.39 47920.0 1580.0 0.12 -0.1929 -0.4699 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L09 compound treatment 38480.0 -8940.0 -0.52 36720.0 -9620.0 -0.73 -0.8809 -0.9861 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L10 compound treatment 34200.0 -13200.0 -0.77 41000.0 -5340.0 -0.4 -0.8272 -0.9553 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L11 compound treatment 34520.0 -12900.0 -0.75 40320.0 -6020.0 -0.46 -0.8505 -0.9718 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L12 compound treatment 34160.0 -13300.0 -0.77 39680.0 -6660.0 -0.5 -0.8995 -0.9791 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L13 compound treatment 33800.0 -13600.0 -0.79 36640.0 -9700.0 -0.73 -1.0769 -0.9993 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L14 compound treatment 38280.0 -9140.0 -0.53 41800.0 -4540.0 -0.34 -0.6172 -0.978 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L15 compound treatment 39000.0 -8420.0 -0.49 43640.0 -2700.0 -0.2 -0.4892 -0.9252 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L16 compound treatment 37600.0 -9820.0 -0.57 41400.0 -4940.0 -0.37 -0.6665 -0.9792 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L17 compound treatment 49080.0 1660.0 0.1 38920.0 -7420.0 -0.56 -0.3289 -0.5774 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L18 compound treatment 32840.0 -14600.0 -0.84 43960.0 -2380.0 -0.18 -0.7245 -0.8389 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L19 compound treatment 38600.0 -8820.0 -0.51 40960.0 -5380.0 -0.41 -0.649 -0.9936 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L20 compound treatment 37120.0 -10300.0 -0.6 36400.0 -9940.0 -0.75 -0.9537 -0.9934 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L21 compound treatment 34520.0 -12900.0 -0.75 45840.0 -496.0 -0.04 -0.555 -0.7417 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L22 compound treatment 36400.0 -11000.0 -0.64 42680.0 -3660.0 -0.28 -0.6471 -0.93 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L23 mock treatment 44280.0 -3140.0 -0.18 39440.0 -6900.0 -0.52 -0.4977 -0.9004 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 L24 mock treatment 44840.0 -2580.0 -0.15 45520.0 -816.0 -0.06 -0.1493 -0.9237 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M01 compound treatment 50840.0 3420.0 0.2 50400.0 4060.0 0.31 0.3577 0.9774 1597861 TimTec1_008502 O=S1(=O)CC(NCc2ccccc2)C=C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M02 compound treatment 39120.0 -8300.0 -0.48 41520.0 -4820.0 -0.36 -0.5978 -0.9907 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M03 compound treatment 39640.0 -7780.0 -0.45 43560.0 -2780.0 -0.21 -0.4673 -0.9397 1709566 TimTec1_008503 Fc1ccc(NC(=O)C2CCCO2)cc1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M04 compound treatment 37480.0 -9940.0 -0.58 37800.0 -8540.0 -0.65 -0.8641 -0.9983 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M05 compound treatment 39240.0 -8180.0 -0.47 42360.0 -3980.0 -0.3 -0.5479 -0.976 3211577 TimTec1_008504 CC(C)NC(=O)C1COc2ccccc2O1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M06 compound treatment 37440.0 -9980.0 -0.58 36200.0 -10100.0 -0.77 -0.9513 -0.9903 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M07 compound treatment 39400.0 -8020.0 -0.46 40720.0 -5620.0 -0.43 -0.6291 -0.999 1778660 TimTec1_008505 COC(=O)c1c(Cl)n2cnccc2c1C(=O)OC 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M08 compound treatment 35640.0 -11800.0 -0.68 43640.0 -2700.0 -0.2 -0.6269 -0.8801 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M09 compound treatment 37280.0 -10100.0 -0.59 41800.0 -4540.0 -0.34 -0.6582 -0.9673 3211578 TimTec1_008506 CCCc1noc2CC(C)(C)C/C(=N/O)/c12 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M10 compound treatment 33000.0 -14400.0 -0.84 34160.0 -12200.0 -0.92 -1.2424 -0.9988 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M11 compound treatment 37840.0 -9580.0 -0.55 38960.0 -7380.0 -0.56 -0.7872 -1.0 1923180 TimTec1_008507 CC1(C)CC(=O)C(=CNCCN2CCNCC2)C(=O)C1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M12 compound treatment 37760.0 -9660.0 -0.56 35040.0 -11300.0 -0.86 -1.0003 -0.9789 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M13 compound treatment 18640.0 -28800.0 -1.67 19320.0 -27000.0 -2.04 -2.625 -0.9949 3087423 TimTec1_008508 C(Nc1ncn[nH]1)c2ccc(NCc3cccc4ccccc34)cc2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M14 compound treatment 41760.0 -5660.0 -0.33 43800.0 -2540.0 -0.19 -0.3676 -0.9675 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M15 compound treatment 40440.0 -6980.0 -0.4 38160.0 -8180.0 -0.62 -0.7235 -0.9787 3211579 TimTec1_008509 OC(=O)C1=CC2c3ccccc3C1c4ccccc24 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M16 compound treatment 39000.0 -8420.0 -0.49 43120.0 -3220.0 -0.24 -0.517 -0.9485 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M17 compound treatment 41720.0 -5700.0 -0.33 42680.0 -3660.0 -0.28 -0.4292 -0.9961 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M18 compound treatment 43400.0 -4020.0 -0.23 42560.0 -3780.0 -0.29 -0.3668 -0.9948 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M19 compound treatment 38520.0 -8900.0 -0.52 39720.0 -6620.0 -0.5 -0.7187 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M20 compound treatment 37160.0 -10300.0 -0.59 38680.0 -7660.0 -0.58 -0.8301 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M21 compound treatment 37800.0 -9620.0 -0.56 33240.0 -13100.0 -0.99 -1.095 -0.9629 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M22 compound treatment 34920.0 -12500.0 -0.72 40200.0 -6140.0 -0.46 -0.8405 -0.977 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M23 mock treatment 43640.0 -3780.0 -0.22 42320.0 -4020.0 -0.3 -0.3698 -0.987 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 M24 mock treatment 43160.0 -4260.0 -0.25 47480.0 1140.0 0.09 -0.1133 -0.4331 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N01 compound treatment 41040.0 -6380.0 -0.37 47560.0 1220.0 0.09 -0.1958 -0.514 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N02 compound treatment 39920.0 -7500.0 -0.43 40920.0 -5420.0 -0.41 -0.5971 -0.9996 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N03 compound treatment 40840.0 -6580.0 -0.38 42720.0 -3620.0 -0.27 -0.4631 -0.9868 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N04 compound treatment 38640.0 -8780.0 -0.51 33640.0 -12700.0 -0.96 -1.0392 -0.9557 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N05 compound treatment 35680.0 -11700.0 -0.68 35640.0 -10700.0 -0.81 -1.0534 -0.9962 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N06 compound treatment 39160.0 -8260.0 -0.48 35600.0 -10700.0 -0.81 -0.913 -0.9681 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N07 compound treatment 32320.0 -15100.0 -0.87 30400.0 -15900.0 -1.21 -1.4715 -0.9875 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N08 compound treatment 29720.0 -17700.0 -1.03 32840.0 -13500.0 -1.02 -1.4475 -1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N09 compound treatment 31160.0 -16300.0 -0.94 28600.0 -17700.0 -1.34 -1.6154 -0.985 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N10 compound treatment 34400.0 -13000.0 -0.75 33680.0 -12700.0 -0.96 -1.2108 -0.993 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N11 compound treatment 39400.0 -8020.0 -0.46 42960.0 -3380.0 -0.26 -0.5092 -0.9604 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N12 compound treatment 34080.0 -13300.0 -0.77 30520.0 -15800.0 -1.2 -1.393 -0.9776 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N13 compound treatment 36840.0 -10600.0 -0.61 31440.0 -14900.0 -1.13 -1.2307 -0.959 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N14 compound treatment 36560.0 -10900.0 -0.63 38920.0 -7420.0 -0.56 -0.8418 -0.9984 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N15 compound treatment 45480.0 -1940.0 -0.11 44520.0 -1820.0 -0.14 -0.1766 -0.995 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N16 compound treatment 38640.0 -8780.0 -0.51 38480.0 -7860.0 -0.59 -0.7801 -0.997 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N17 compound treatment 43440.0 -3980.0 -0.23 43240.0 -3100.0 -0.23 -0.3287 -1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N18 compound treatment 39440.0 -7980.0 -0.46 39840.0 -6500.0 -0.49 -0.6746 -0.9995 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N19 compound treatment 44160.0 -3260.0 -0.19 37880.0 -8460.0 -0.64 -0.5861 -0.8783 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N20 compound treatment 46240.0 -1180.0 -0.07 40120.0 -6220.0 -0.47 -0.381 -0.8013 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N21 compound treatment 41840.0 -5580.0 -0.32 35680.0 -10700.0 -0.81 -0.7989 -0.9194 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N22 compound treatment 43840.0 -3580.0 -0.21 42440.0 -3900.0 -0.29 -0.3552 -0.9851 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N23 mock treatment 42600.0 -4820.0 -0.28 44600.0 -1740.0 -0.13 -0.2903 -0.9409 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 N24 mock treatment 43200.0 -4220.0 -0.24 39640.0 -6700.0 -0.51 -0.5312 -0.9441 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O01 compound treatment 47080.0 -339.0 -0.02 59480.0 13100.0 0.99 0.6896 0.693 3211580 TimTec1_008510 Nc1nc2ccc(cc2s1)C(=O)OC3CCCCC3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O02 compound treatment 42040.0 -5380.0 -0.31 41840.0 -4500.0 -0.34 -0.461 -0.999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O03 compound treatment 30520.0 -16900.0 -0.98 30600.0 -15700.0 -1.19 -1.5346 -0.9953 1790435 TimTec1_008511 Cc1cc(C(=O)OCC(=O)Nc2sc3CCCCc3c2C#N)c4ccccc4n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O04 compound treatment 39400.0 -8020.0 -0.46 37120.0 -9220.0 -0.7 -0.8218 -0.9805 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O05 compound treatment 45120.0 -2300.0 -0.13 46440.0 104.0 0.01 -0.0886 -0.6643 3211581 TimTec1_008512 CN1C2=C(C(C3=C1CCCC3=O)c4ccccc4)C(=O)CCC2 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O06 compound treatment 42480.0 -4940.0 -0.29 37080.0 -9260.0 -0.7 -0.6978 -0.922 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O07 compound treatment 47240.0 -179.0 -0.01 40600.0 -5740.0 -0.43 -0.3144 -0.7238 1677589 TimTec1_008513 O=C(Cc1cccc2ccccc12)NCC3CCCO3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O08 compound treatment 39480.0 -7940.0 -0.46 33920.0 -12400.0 -0.94 -0.9898 -0.946 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O09 compound treatment 14240.0 -33200.0 -1.92 15480.0 -30900.0 -2.34 -3.0108 -0.9953 1210690 TimTec1_008514 COC(=O)CCNc1ccc2OCCOc2c1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O10 compound treatment 40680.0 -6740.0 -0.39 45720.0 -616.0 -0.05 -0.3091 -0.786 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O11 compound treatment 43280.0 -4140.0 -0.24 43320.0 -3020.0 -0.23 -0.331 -0.9997 1483611 TimTec1_008515 CCOC(=O)c1cnc2cc(nn2c1O)c3ccccc3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O12 compound treatment 38040.0 -9380.0 -0.54 36400.0 -9940.0 -0.75 -0.9161 -0.9873 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O13 compound treatment 31440.0 -16000.0 -0.93 35920.0 -10400.0 -0.79 -1.2121 -0.9968 3087424 TimTec1_008516 O=C(CC(c1ccccc1)c2ccccc2)Nc3nnc[nH]3 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O14 compound treatment 44720.0 -2700.0 -0.16 41800.0 -4540.0 -0.34 -0.3534 -0.9366 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O15 compound treatment 13200.0 -34200.0 -1.98 16200.0 -30100.0 -2.28 -3.0149 -0.9976 3211582 TimTec1_008517 Cc1cc(NCc2ccccc2)n3ncnc3n1 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O16 compound treatment 43680.0 -3740.0 -0.22 44320.0 -2020.0 -0.15 -0.2611 -0.9853 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O17 compound treatment 34880.0 -12500.0 -0.73 37160.0 -9180.0 -0.69 -1.0048 -0.9997 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O18 compound treatment 49760.0 2340.0 0.14 45760.0 -576.0 -0.04 0.0651 0.4567 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O19 compound treatment 47280.0 -139.0 -0.01 49000.0 2660.0 0.2 0.1369 0.6784 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O20 compound treatment 39840.0 -7580.0 -0.44 43040.0 -3300.0 -0.25 -0.4869 -0.9641 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O21 compound treatment 49800.0 2380.0 0.14 49680.0 3340.0 0.25 0.2765 0.9593 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O22 compound treatment 50400.0 2980.0 0.17 46320.0 -16.3 0.0 0.1213 0.7021 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O23 mock treatment 46040.0 -1380.0 -0.08 48080.0 1740.0 0.13 0.0368 0.2388 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 O24 mock treatment 49720.0 2300.0 0.13 46680.0 344.0 0.03 0.1127 0.8295 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P01 compound treatment 41680.0 -5740.0 -0.33 38440.0 -7900.0 -0.6 -0.6577 -0.9617 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P02 compound treatment 36280.0 -11100.0 -0.65 38160.0 -8180.0 -0.62 -0.894 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P03 compound treatment 38680.0 -8740.0 -0.51 35440.0 -10900.0 -0.82 -0.9412 -0.9725 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P04 compound treatment 35160.0 -12300.0 -0.71 29840.0 -16500.0 -1.25 -1.3852 -0.9642 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P05 compound treatment 34680.0 -12700.0 -0.74 30160.0 -16200.0 -1.22 -1.3877 -0.9706 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P06 compound treatment 33680.0 -13700.0 -0.8 32680.0 -13700.0 -1.03 -1.2938 -0.9917 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P07 compound treatment 30840.0 -16600.0 -0.96 26960.0 -19400.0 -1.47 -1.7163 -0.9789 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P08 compound treatment 32720.0 -14700.0 -0.85 28600.0 -17700.0 -1.34 -1.5515 -0.9759 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P09 compound treatment 32680.0 -14700.0 -0.85 26960.0 -19400.0 -1.47 -1.6409 -0.9669 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P10 compound treatment 29840.0 -17600.0 -1.02 35960.0 -10400.0 -0.79 -1.2755 -0.9918 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P11 compound treatment 29880.0 -17500.0 -1.02 23520.0 -22800.0 -1.73 -1.9397 -0.968 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P12 compound treatment 31800.0 -15600.0 -0.9 40240.0 -6100.0 -0.46 -0.9662 -0.9512 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P13 compound treatment 26800.0 -20600.0 -1.19 30520.0 -15800.0 -1.2 -1.6913 -1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P14 compound treatment 30040.0 -17400.0 -1.01 32200.0 -14100.0 -1.07 -1.4686 -0.9995 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P15 compound treatment 27560.0 -19900.0 -1.15 29200.0 -17100.0 -1.3 -1.7308 -0.9982 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P16 compound treatment 30400.0 -17000.0 -0.99 27600.0 -18700.0 -1.42 -1.7001 -0.9842 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P17 compound treatment 36040.0 -11400.0 -0.66 32880.0 -13500.0 -1.02 -1.1864 -0.9778 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P18 compound treatment 28240.0 -19200.0 -1.11 31520.0 -14800.0 -1.12 -1.5787 -1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P19 compound treatment 29040.0 -18400.0 -1.06 33640.0 -12700.0 -0.96 -1.4325 -0.9987 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P20 compound treatment 28920.0 -18500.0 -1.07 37200.0 -9140.0 -0.69 -1.2469 -0.9775 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P21 compound treatment 30760.0 -16700.0 -0.97 35800.0 -10500.0 -0.8 -1.2464 -0.9955 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P22 compound treatment 41120.0 -6300.0 -0.36 35160.0 -11200.0 -0.85 -0.8562 -0.9294 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P23 mock treatment 42400.0 -5020.0 -0.29 43520.0 -2820.0 -0.21 -0.3563 -0.9884 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.2087 P24 mock treatment 47560.0 141.0 0.01 40840.0 -5500.0 -0.42 -0.2884 -0.6931 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A01 mock treatment 9600.0 -26300.0 -1.52 36080.0 -16500.0 -1.25 -1.9603 -0.9952 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A02 mock treatment 24240.0 -11600.0 -0.67 40720.0 -11900.0 -0.9 -1.1122 -0.99 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A03 mock treatment 36160.0 285.0 0.02 45400.0 -7190.0 -0.54 -0.3733 -0.6853 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A04 mock treatment 36320.0 445.0 0.03 51760.0 -833.0 -0.06 -0.0264 -0.3868 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A05 mock treatment 41800.0 5930.0 0.34 48440.0 -4150.0 -0.31 0.0204 0.0439 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A06 mock treatment 41320.0 5450.0 0.32 50640.0 -1950.0 -0.15 0.1185 0.3402 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A07 mock treatment 44520.0 8650.0 0.5 51080.0 -1510.0 -0.11 0.2732 0.5317 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A08 mock treatment 43880.0 8010.0 0.46 55880.0 3290.0 0.25 0.5039 0.9574 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A09 mock treatment 41280.0 5410.0 0.31 55880.0 3290.0 0.25 0.3974 0.9935 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A10 mock treatment 29400.0 -6470.0 -0.38 46760.0 -5830.0 -0.44 -0.5775 -0.9967 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A11 mock treatment 30720.0 -5150.0 -0.3 49880.0 -2710.0 -0.21 -0.3564 -0.9833 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A12 mock treatment 28680.0 -7190.0 -0.42 45400.0 -7190.0 -0.54 -0.6798 -0.9913 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A13 mock treatment 30800.0 -5070.0 -0.29 52400.0 -193.0 -0.01 -0.2183 -0.7414 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A14 mock treatment 35440.0 -435.0 -0.03 45960.0 -6630.0 -0.5 -0.3729 -0.7416 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A15 mock treatment 32480.0 -3390.0 -0.2 47280.0 -5310.0 -0.4 -0.4235 -0.9459 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A16 mock treatment 34240.0 -1630.0 -0.09 41000.0 -11600.0 -0.88 -0.6875 -0.7789 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A17 mock treatment 31560.0 -4310.0 -0.25 44200.0 -8390.0 -0.64 -0.626 -0.9169 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A18 mock treatment 29080.0 -6790.0 -0.39 46520.0 -6070.0 -0.46 -0.6034 -0.997 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A19 mock treatment 31920.0 -3950.0 -0.23 44360.0 -8230.0 -0.62 -0.6027 -0.9077 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A20 mock treatment 29560.0 -6310.0 -0.37 45920.0 -6670.0 -0.51 -0.6159 -0.9875 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A21 mock treatment 35480.0 -395.0 -0.02 45040.0 -7550.0 -0.57 -0.4205 -0.7348 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A22 mock treatment 36680.0 805.0 0.05 48720.0 -3870.0 -0.29 -0.1743 -0.5872 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A23 mock treatment 37720.0 1850.0 0.11 53400.0 807.0 0.06 0.1188 0.9647 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base A24 mock treatment 47280.0 11400.0 0.66 54520.0 1930.0 0.15 0.5704 0.8429 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B01 mock treatment 17760.0 -18100.0 -1.05 39920.0 -12700.0 -0.96 -1.4205 -0.999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B02 mock treatment 26000.0 -9870.0 -0.57 49680.0 -2910.0 -0.22 -0.5605 -0.9141 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B03 mock treatment 38720.0 2850.0 0.16 58520.0 5930.0 0.45 0.4338 0.9076 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B04 mock treatment 42280.0 6410.0 0.37 58000.0 5410.0 0.41 0.5518 0.9988 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B05 mock treatment 42720.0 6850.0 0.4 58200.0 5610.0 0.42 0.5805 0.9994 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B06 mock treatment 47440.0 11600.0 0.67 57720.0 5130.0 0.39 0.7482 0.9663 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B07 mock treatment 44120.0 8250.0 0.48 54320.0 1730.0 0.13 0.4302 0.8686 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B08 mock treatment 31280.0 -4590.0 -0.27 46320.0 -6270.0 -0.47 -0.524 -0.9626 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B09 mock treatment 22800.0 -13100.0 -0.76 43920.0 -8670.0 -0.66 -0.9999 -0.9975 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B10 mock treatment 26360.0 -9510.0 -0.55 46280.0 -6310.0 -0.48 -0.7277 -0.9975 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B11 mock treatment 29080.0 -6790.0 -0.39 47400.0 -5190.0 -0.39 -0.5563 -1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B12 mock treatment 28480.0 -7390.0 -0.43 48440.0 -4150.0 -0.31 -0.5253 -0.9884 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B13 mock treatment 29640.0 -6230.0 -0.36 50200.0 -2390.0 -0.18 -0.3835 -0.9491 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B14 mock treatment 27920.0 -7950.0 -0.46 50240.0 -2350.0 -0.18 -0.4519 -0.9145 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B15 mock treatment 23480.0 -12400.0 -0.72 49520.0 -3070.0 -0.23 -0.6723 -0.8906 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B16 mock treatment 29640.0 -6230.0 -0.36 48200.0 -4390.0 -0.33 -0.4906 -0.9991 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B17 mock treatment 32280.0 -3590.0 -0.21 51480.0 -1110.0 -0.08 -0.2069 -0.9207 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B18 mock treatment 30040.0 -5830.0 -0.34 52720.0 127.0 0.01 -0.2323 -0.6868 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B19 mock treatment 38880.0 3010.0 0.17 54480.0 1890.0 0.14 0.2241 0.9952 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B20 mock treatment 42960.0 7090.0 0.41 60640.0 8050.0 0.61 0.721 0.9816 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B21 mock treatment 44200.0 8330.0 0.48 57760.0 5170.0 0.39 0.6176 0.9946 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B22 mock treatment 46480.0 10600.0 0.61 58000.0 5410.0 0.41 0.7239 0.9805 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B23 mock treatment 49160.0 13300.0 0.77 68680.0 16100.0 1.22 1.4053 0.9755 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base B24 mock treatment 52240.0 16400.0 0.95 67760.0 15200.0 1.15 1.4822 0.9955 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C01 mock treatment 15320.0 -20600.0 -1.19 51000.0 -1590.0 -0.12 -0.9274 -0.7748 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C02 mock treatment 21960.0 -13900.0 -0.81 56040.0 3450.0 0.26 -0.3856 -0.4551 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C03 mock treatment 28920.0 -6950.0 -0.4 54160.0 1570.0 0.12 -0.2011 -0.4787 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C04 mock treatment 39800.0 3930.0 0.23 57480.0 4890.0 0.37 0.4224 0.9727 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C05 mock treatment 38880.0 3010.0 0.17 57600.0 5010.0 0.38 0.3911 0.9377 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C06 mock treatment 48240.0 12400.0 0.72 52560.0 -33.5 0.0 0.5048 0.7046 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C07 mock treatment 31120.0 -4750.0 -0.28 52360.0 -233.0 -0.02 -0.2073 -0.7509 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C08 mock treatment 28800.0 -7070.0 -0.41 47880.0 -4710.0 -0.36 -0.5421 -0.9976 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C09 mock treatment 29320.0 -6550.0 -0.38 46120.0 -6470.0 -0.49 -0.615 -0.9921 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C10 mock treatment 28000.0 -7870.0 -0.46 50920.0 -1670.0 -0.13 -0.4122 -0.8705 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C11 mock treatment 31080.0 -4790.0 -0.28 48640.0 -3950.0 -0.3 -0.408 -0.9993 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C12 mock treatment 33400.0 -2470.0 -0.14 47080.0 -5510.0 -0.42 -0.3965 -0.8985 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C13 mock treatment 29600.0 -6270.0 -0.36 44560.0 -8030.0 -0.61 -0.687 -0.9698 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C14 mock treatment 26200.0 -9670.0 -0.56 46640.0 -5950.0 -0.45 -0.715 -0.9941 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C15 mock treatment 27040.0 -8830.0 -0.51 46680.0 -5910.0 -0.45 -0.6785 -0.9978 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C16 mock treatment 29640.0 -6230.0 -0.36 50600.0 -1990.0 -0.15 -0.3621 -0.925 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C17 mock treatment 32880.0 -2990.0 -0.17 52360.0 -233.0 -0.02 -0.1352 -0.7751 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C18 mock treatment 40280.0 4410.0 0.26 53120.0 527.0 0.04 0.2087 0.8077 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C19 mock treatment 40040.0 4170.0 0.24 53040.0 447.0 0.03 0.1945 0.7984 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C20 mock treatment 51840.0 16000.0 0.92 62840.0 10200.0 0.78 1.2025 0.9962 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C21 mock treatment 50080.0 14200.0 0.82 63360.0 10800.0 0.81 1.1582 1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C22 mock treatment 52800.0 16900.0 0.98 63440.0 10800.0 0.82 1.2739 0.9961 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C23 mock treatment 53640.0 17800.0 1.03 68720.0 16100.0 1.22 1.591 0.9964 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base C24 mock treatment 51680.0 15800.0 0.92 58840.0 6250.0 0.47 0.9819 0.9527 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D01 mock treatment 16480.0 -19400.0 -1.12 53040.0 447.0 0.03 -0.7707 -0.6855 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D02 mock treatment 20920.0 -15000.0 -0.87 56520.0 3930.0 0.3 -0.4025 -0.4394 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D03 mock treatment 34800.0 -1070.0 -0.06 65520.0 12900.0 0.98 0.6479 0.6608 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D04 mock treatment 41360.0 5490.0 0.32 55240.0 2650.0 0.2 0.3664 0.9752 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D05 mock treatment 48000.0 12100.0 0.7 50440.0 -2150.0 -0.16 0.3815 0.529 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D06 mock treatment 40000.0 4130.0 0.24 46200.0 -6390.0 -0.48 -0.1732 -0.3209 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D07 mock treatment 27680.0 -8190.0 -0.47 44680.0 -7910.0 -0.6 -0.7593 -0.9934 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D08 mock treatment 26840.0 -9030.0 -0.52 43400.0 -9190.0 -0.7 -0.8622 -0.9901 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D09 mock treatment 28800.0 -7070.0 -0.41 49760.0 -2830.0 -0.21 -0.4415 -0.9543 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D10 mock treatment 34200.0 -1670.0 -0.1 49600.0 -2990.0 -0.23 -0.2288 -0.9284 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D11 mock treatment 34160.0 -1710.0 -0.1 51560.0 -1030.0 -0.08 -0.1256 -0.993 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D12 mock treatment 31360.0 -4510.0 -0.26 50920.0 -1670.0 -0.13 -0.2745 -0.9446 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D13 mock treatment 26000.0 -9870.0 -0.57 39040.0 -13600.0 -1.03 -1.13 -0.962 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D14 mock treatment 28400.0 -7470.0 -0.43 49640.0 -2950.0 -0.22 -0.4643 -0.9527 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D15 mock treatment 26960.0 -8910.0 -0.52 47920.0 -4670.0 -0.35 -0.6154 -0.983 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D16 mock treatment 30640.0 -5230.0 -0.3 52880.0 287.0 0.02 -0.1991 -0.6549 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D17 mock treatment 38080.0 2210.0 0.13 61360.0 8770.0 0.66 0.5596 0.828 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D18 mock treatment 42040.0 6170.0 0.36 60120.0 7530.0 0.57 0.6554 0.9747 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D19 mock treatment 49000.0 13100.0 0.76 62440.0 9850.0 0.75 1.0647 0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D20 mock treatment 54200.0 18300.0 1.06 65800.0 13200.0 1.0 1.4576 0.9995 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D21 mock treatment 47520.0 11600.0 0.67 60600.0 8010.0 0.61 0.9056 0.9986 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D22 mock treatment 56760.0 20900.0 1.21 65040.0 12400.0 0.94 1.5218 0.9923 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D23 mock treatment 55280.0 19400.0 1.12 63520.0 10900.0 0.83 1.3798 0.9886 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base D24 mock treatment 58880.0 23000.0 1.33 62600.0 10000.0 0.76 1.4781 0.9641 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E01 mock treatment 17120.0 -18800.0 -1.09 57920.0 5330.0 0.4 -0.4832 -0.417 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E02 mock treatment 25440.0 -10400.0 -0.6 55280.0 2690.0 0.2 -0.2837 -0.4448 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E03 mock treatment 40120.0 4250.0 0.25 60720.0 8130.0 0.62 0.6089 0.9191 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E04 mock treatment 42520.0 6650.0 0.39 59720.0 7130.0 0.54 0.6537 0.9863 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E05 mock treatment 46880.0 11000.0 0.64 50240.0 -2350.0 -0.18 0.3249 0.4908 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E06 mock treatment 31560.0 -4310.0 -0.25 44040.0 -8550.0 -0.65 -0.6346 -0.9143 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E07 mock treatment 25720.0 -10200.0 -0.59 42600.0 -9990.0 -0.76 -0.9509 -0.9923 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E08 mock treatment 27720.0 -8150.0 -0.47 44320.0 -8270.0 -0.63 -0.7769 -0.9903 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E09 mock treatment 32120.0 -3750.0 -0.22 43720.0 -8870.0 -0.67 -0.6288 -0.8906 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E10 mock treatment 33880.0 -1990.0 -0.12 50880.0 -1710.0 -0.13 -0.1734 -0.9983 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E11 mock treatment 31800.0 -4070.0 -0.24 42040.0 -10600.0 -0.8 -0.7318 -0.8785 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E12 mock treatment 30800.0 -5070.0 -0.29 42240.0 -10400.0 -0.78 -0.7621 -0.9104 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E13 mock treatment 27960.0 -7910.0 -0.46 43600.0 -8990.0 -0.68 -0.8056 -0.9815 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E14 mock treatment 33480.0 -2390.0 -0.14 50440.0 -2150.0 -0.16 -0.2134 -0.9968 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E15 mock treatment 32360.0 -3510.0 -0.2 53960.0 1370.0 0.1 -0.0708 -0.3102 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E16 mock treatment 34000.0 -1870.0 -0.11 56160.0 3570.0 0.27 0.1141 0.3921 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E17 mock treatment 39560.0 3690.0 0.21 52640.0 46.5 0.0 0.1535 0.7187 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E18 mock treatment 44120.0 8250.0 0.48 60080.0 7490.0 0.57 0.7385 0.9964 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E19 mock treatment 50840.0 15000.0 0.87 57040.0 4450.0 0.34 0.8511 0.9151 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E20 mock treatment 50640.0 14800.0 0.86 65840.0 13200.0 1.0 1.3139 0.9969 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E21 mock treatment 54960.0 19100.0 1.11 60200.0 7610.0 0.58 1.189 0.9537 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E22 mock treatment 51280.0 15400.0 0.89 59440.0 6850.0 0.52 0.9976 0.9666 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E23 mock treatment 53440.0 17600.0 1.02 65640.0 13000.0 0.99 1.4179 0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base E24 mock treatment 54840.0 19000.0 1.1 62240.0 9650.0 0.73 1.2933 0.9803 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F01 mock treatment 14200.0 -21700.0 -1.26 45080.0 -7510.0 -0.57 -1.2901 -0.9358 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F02 mock treatment 17840.0 -18000.0 -1.04 47080.0 -5510.0 -0.42 -1.034 -0.9189 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F03 mock treatment 20680.0 -15200.0 -0.88 45920.0 -6670.0 -0.51 -0.9797 -0.9652 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F04 mock treatment 47320.0 11400.0 0.66 50680.0 -1910.0 -0.14 0.3665 0.5399 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F05 mock treatment 38560.0 2690.0 0.16 51360.0 -1230.0 -0.09 0.044 0.2425 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F06 mock treatment 24600.0 -11300.0 -0.65 40640.0 -12000.0 -0.9 -1.1017 -0.9872 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F07 mock treatment 23720.0 -12200.0 -0.7 44120.0 -8470.0 -0.64 -0.9515 -0.9989 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F08 mock treatment 28600.0 -7270.0 -0.42 45560.0 -7030.0 -0.53 -0.6745 -0.9933 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F09 mock treatment 32040.0 -3830.0 -0.22 47600.0 -4990.0 -0.38 -0.4244 -0.9679 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F10 mock treatment 35960.0 85.3 0.0 52560.0 -33.5 0.0 0.0017 0.3068 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F11 mock treatment 28760.0 -7110.0 -0.41 51480.0 -1110.0 -0.08 -0.3511 -0.8344 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F12 mock treatment 28680.0 -7190.0 -0.42 49600.0 -2990.0 -0.23 -0.455 -0.959 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F13 mock treatment 30000.0 -5870.0 -0.34 45360.0 -7230.0 -0.55 -0.6278 -0.9738 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F14 mock treatment 27600.0 -8270.0 -0.48 54280.0 1690.0 0.13 -0.2487 -0.5013 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F15 mock treatment 30440.0 -5430.0 -0.31 57960.0 5370.0 0.41 0.0646 0.1257 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F16 mock treatment 38280.0 2410.0 0.14 55040.0 2450.0 0.19 0.2295 0.9902 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F17 mock treatment 45160.0 9290.0 0.54 63080.0 10500.0 0.79 0.9417 0.982 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F18 mock treatment 51880.0 16000.0 0.93 59440.0 6850.0 0.52 1.0222 0.9622 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F19 mock treatment 56800.0 20900.0 1.21 63800.0 11200.0 0.85 1.4571 0.9847 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F20 mock treatment 58920.0 23000.0 1.34 67720.0 15100.0 1.14 1.7538 0.9971 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F21 mock treatment 57120.0 21200.0 1.23 66400.0 13800.0 1.05 1.6094 0.9967 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F22 mock treatment 55800.0 19900.0 1.15 62000.0 9410.0 0.71 1.3198 0.973 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F23 mock treatment 65480.0 29600.0 1.72 65520.0 12900.0 0.98 1.9048 0.9646 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base F24 mock treatment 63000.0 27100.0 1.57 65800.0 13200.0 1.0 1.8181 0.9761 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G01 mock treatment 18000.0 -17900.0 -1.04 55920.0 3330.0 0.25 -0.5542 -0.52 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G02 mock treatment 33120.0 -2750.0 -0.16 50600.0 -1990.0 -0.15 -0.2196 -0.9996 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G03 mock treatment 41120.0 5250.0 0.3 48600.0 -3990.0 -0.3 0.0011 0.0027 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G04 mock treatment 43120.0 7250.0 0.42 42360.0 -10200.0 -0.77 -0.2509 -0.2848 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G05 mock treatment 35160.0 -715.0 -0.04 43800.0 -8790.0 -0.67 -0.4999 -0.7496 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G06 mock treatment 23960.0 -11900.0 -0.69 40960.0 -11600.0 -0.88 -1.1108 -0.9927 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G07 mock treatment 27600.0 -8270.0 -0.48 37960.0 -14600.0 -1.11 -1.1222 -0.9298 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G08 mock treatment 30280.0 -5590.0 -0.32 49960.0 -2630.0 -0.2 -0.3702 -0.9727 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G09 mock treatment 32760.0 -3110.0 -0.18 49080.0 -3510.0 -0.27 -0.3157 -0.9822 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G10 mock treatment 30680.0 -5190.0 -0.3 52240.0 -353.0 -0.03 -0.2317 -0.7669 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G11 mock treatment 24200.0 -11700.0 -0.68 45400.0 -7190.0 -0.54 -0.8633 -0.9942 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G12 mock treatment 26640.0 -9230.0 -0.54 43480.0 -9110.0 -0.69 -0.8661 -0.9921 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G13 mock treatment 22720.0 -13200.0 -0.76 45360.0 -7230.0 -0.55 -0.9261 -0.9868 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G14 mock treatment 27880.0 -7990.0 -0.46 52560.0 -33.5 0.0 -0.3293 -0.711 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G15 mock treatment 35160.0 -715.0 -0.04 55160.0 2570.0 0.19 0.1081 0.5442 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G16 mock treatment 40160.0 4290.0 0.25 52840.0 247.0 0.02 0.1888 0.7581 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G17 mock treatment 49200.0 13300.0 0.77 58320.0 5730.0 0.43 0.8524 0.9628 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G18 mock treatment 53400.0 17500.0 1.02 62720.0 10100.0 0.77 1.26 0.9904 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G19 mock treatment 51040.0 15200.0 0.88 58360.0 5770.0 0.44 0.9299 0.9479 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G20 mock treatment 50800.0 14900.0 0.86 61600.0 9010.0 0.68 1.0935 0.9931 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G21 mock treatment 56600.0 20700.0 1.2 59120.0 6530.0 0.49 1.1984 0.923 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G22 mock treatment 55200.0 19300.0 1.12 62760.0 10200.0 0.77 1.3359 0.9833 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G23 mock treatment 54760.0 18900.0 1.09 58880.0 6290.0 0.48 1.1102 0.9304 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base G24 mock treatment 53760.0 17900.0 1.04 58600.0 6010.0 0.45 1.0542 0.9316 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H01 mock treatment 15840.0 -20000.0 -1.16 55800.0 3210.0 0.24 -0.6492 -0.5474 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H02 mock treatment 29840.0 -6030.0 -0.35 51840.0 -753.0 -0.06 -0.2876 -0.8117 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H03 mock treatment 45280.0 9410.0 0.54 47640.0 -4950.0 -0.37 0.1202 0.1817 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H04 mock treatment 43840.0 7970.0 0.46 46640.0 -5950.0 -0.45 0.0077 0.0119 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H05 mock treatment 30720.0 -5150.0 -0.3 37920.0 -14700.0 -1.11 -0.9966 -0.8665 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H06 mock treatment 23160.0 -12700.0 -0.74 36680.0 -15900.0 -1.2 -1.3726 -0.9722 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H07 mock treatment 22400.0 -13500.0 -0.78 42040.0 -10600.0 -0.8 -1.1169 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H08 mock treatment 29000.0 -6870.0 -0.4 50120.0 -2470.0 -0.19 -0.414 -0.9407 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H09 mock treatment 33640.0 -2230.0 -0.13 51040.0 -1550.0 -0.12 -0.1747 -0.9988 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H10 mock treatment 26440.0 -9430.0 -0.55 50080.0 -2510.0 -0.19 -0.5211 -0.9002 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H11 mock treatment 23560.0 -12300.0 -0.71 48480.0 -4110.0 -0.31 -0.7247 -0.9309 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H12 mock treatment 26840.0 -9030.0 -0.52 44160.0 -8430.0 -0.64 -0.8215 -0.9951 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H13 mock treatment 23560.0 -12300.0 -0.71 49960.0 -2630.0 -0.2 -0.6455 -0.8713 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H14 mock treatment 28720.0 -7150.0 -0.41 62960.0 10400.0 0.78 0.2617 0.2949 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H15 mock treatment 38680.0 2810.0 0.16 59400.0 6810.0 0.52 0.4792 0.8871 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H16 mock treatment 41680.0 5810.0 0.34 59960.0 7370.0 0.56 0.6321 0.9707 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H17 mock treatment 50680.0 14800.0 0.86 62520.0 9930.0 0.75 1.1379 0.9978 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H18 mock treatment 56040.0 20200.0 1.17 63480.0 10900.0 0.82 1.4088 0.9854 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H19 mock treatment 62680.0 26800.0 1.55 66520.0 13900.0 1.05 1.8436 0.9822 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H20 mock treatment 60880.0 25000.0 1.45 61840.0 9250.0 0.7 1.5193 0.9443 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H21 mock treatment 54040.0 18200.0 1.05 61960.0 9370.0 0.71 1.2455 0.9815 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H22 mock treatment 53440.0 17600.0 1.02 59520.0 6930.0 0.52 1.0904 0.9524 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H23 mock treatment 53520.0 17600.0 1.02 64320.0 11700.0 0.89 1.3505 0.9975 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base H24 mock treatment 54280.0 18400.0 1.07 64720.0 12100.0 0.92 1.4031 0.9972 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I01 mock treatment 11000.0 -24900.0 -1.44 55560.0 2970.0 0.22 -0.8603 -0.5898 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I02 mock treatment 31280.0 -4590.0 -0.27 49360.0 -3230.0 -0.24 -0.3613 -0.9991 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I03 mock treatment 37600.0 1730.0 0.1 50400.0 -2190.0 -0.17 -0.0467 -0.2411 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I04 mock treatment 38360.0 2490.0 0.14 44880.0 -7710.0 -0.58 -0.311 -0.5172 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I05 mock treatment 24920.0 -11000.0 -0.63 34640.0 -18000.0 -1.36 -1.4097 -0.9399 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I06 mock treatment 21960.0 -13900.0 -0.81 35240.0 -17400.0 -1.31 -1.4989 -0.9725 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I07 mock treatment 27520.0 -8350.0 -0.48 48360.0 -4230.0 -0.32 -0.5689 -0.9799 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I08 mock treatment 32320.0 -3550.0 -0.21 55040.0 2450.0 0.19 -0.0147 -0.053 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I09 mock treatment 34960.0 -915.0 -0.05 57360.0 4770.0 0.36 0.2177 0.5968 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I10 mock treatment 30360.0 -5510.0 -0.32 44240.0 -8350.0 -0.63 -0.673 -0.95 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I11 mock treatment 26240.0 -9630.0 -0.56 49960.0 -2630.0 -0.2 -0.5357 -0.9037 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I12 mock treatment 25720.0 -10200.0 -0.59 49760.0 -2830.0 -0.21 -0.5677 -0.9065 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I13 mock treatment 25240.0 -10600.0 -0.62 50320.0 -2270.0 -0.17 -0.5574 -0.8713 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I14 mock treatment 29880.0 -5990.0 -0.35 54640.0 2050.0 0.15 -0.1361 -0.3578 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I15 mock treatment 38200.0 2330.0 0.13 57040.0 4450.0 0.34 0.3333 0.9192 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I16 mock treatment 44240.0 8370.0 0.48 59600.0 7010.0 0.53 0.7177 0.999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I17 mock treatment 52960.0 17100.0 0.99 61760.0 9170.0 0.69 1.1906 0.9849 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I18 mock treatment 59880.0 24000.0 1.39 63400.0 10800.0 0.82 1.5619 0.968 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I19 mock treatment 60200.0 24300.0 1.41 61200.0 8610.0 0.65 1.4572 0.9385 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I20 mock treatment 52480.0 16600.0 0.96 65280.0 12700.0 0.96 1.3593 1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I21 mock treatment 58960.0 23100.0 1.34 61440.0 8850.0 0.67 1.4193 0.9488 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I22 mock treatment 57520.0 21600.0 1.25 59200.0 6610.0 0.5 1.2404 0.9187 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I23 mock treatment 50040.0 14200.0 0.82 62880.0 10300.0 0.78 1.1309 0.9997 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base I24 mock treatment 53360.0 17500.0 1.01 66120.0 13500.0 1.02 1.4403 1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J01 mock treatment 7040.0 -28800.0 -1.67 54760.0 2170.0 0.16 -1.0653 -0.6346 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J02 mock treatment 21800.0 -14100.0 -0.82 47440.0 -5150.0 -0.39 -0.8524 -0.943 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J03 mock treatment 34880.0 -995.0 -0.06 48200.0 -4390.0 -0.33 -0.2759 -0.8175 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J04 mock treatment 30080.0 -5790.0 -0.34 42280.0 -10300.0 -0.78 -0.7894 -0.9289 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J05 mock treatment 15720.0 -20200.0 -1.17 36400.0 -16200.0 -1.23 -1.6924 -0.9997 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J06 mock treatment 20080.0 -15800.0 -0.92 35360.0 -17200.0 -1.3 -1.5695 -0.985 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J07 mock treatment 26880.0 -8990.0 -0.52 49080.0 -3510.0 -0.27 -0.5566 -0.9513 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J08 mock treatment 33200.0 -2670.0 -0.15 49560.0 -3030.0 -0.23 -0.2719 -0.9817 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J09 mock treatment 25600.0 -10300.0 -0.6 52280.0 -313.0 -0.02 -0.4377 -0.7347 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J10 mock treatment 26000.0 -9870.0 -0.57 47840.0 -4750.0 -0.36 -0.659 -0.975 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J11 mock treatment 25400.0 -10500.0 -0.61 42480.0 -10100.0 -0.77 -0.9704 -0.9934 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J12 mock treatment 28440.0 -7430.0 -0.43 49680.0 -2910.0 -0.22 -0.4605 -0.9517 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J13 mock treatment 25400.0 -10500.0 -0.61 54200.0 1610.0 0.12 -0.3431 -0.5544 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J14 mock treatment 29440.0 -6430.0 -0.37 51640.0 -953.0 -0.07 -0.3147 -0.8286 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J15 mock treatment 42000.0 6130.0 0.35 57720.0 5130.0 0.39 0.5253 0.999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J16 mock treatment 47000.0 11100.0 0.64 55200.0 2610.0 0.2 0.5953 0.8831 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J17 mock treatment 64400.0 28500.0 1.65 61000.0 8410.0 0.64 1.6186 0.914 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J18 mock treatment 58640.0 22800.0 1.32 67640.0 15000.0 1.14 1.738 0.9973 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J19 mock treatment 59280.0 23400.0 1.36 52040.0 -553.0 -0.04 0.9292 0.6849 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J20 mock treatment 49440.0 13600.0 0.79 57560.0 4970.0 0.38 0.8216 0.943 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J21 mock treatment 52320.0 16400.0 0.95 61360.0 8770.0 0.66 1.143 0.9844 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J22 mock treatment 51400.0 15500.0 0.9 65480.0 12900.0 0.98 1.3258 0.9992 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J23 mock treatment 51320.0 15400.0 0.89 60560.0 7970.0 0.6 1.0592 0.9815 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base J24 mock treatment 51120.0 15200.0 0.88 58000.0 5410.0 0.41 0.914 0.9389 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K01 mock treatment 26280.0 -9590.0 -0.56 40440.0 -12200.0 -0.92 -1.0436 -0.9709 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K02 mock treatment 28280.0 -7590.0 -0.44 42320.0 -10300.0 -0.78 -0.861 -0.9636 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K03 mock treatment 34000.0 -1870.0 -0.11 39120.0 -13500.0 -1.02 -0.798 -0.778 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K04 mock treatment 24080.0 -11800.0 -0.68 31160.0 -21400.0 -1.62 -1.6304 -0.9261 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K05 mock treatment 17520.0 -18400.0 -1.06 25480.0 -27100.0 -2.05 -2.2032 -0.9531 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K06 mock treatment 17760.0 -18100.0 -1.05 35960.0 -16600.0 -1.26 -1.6324 -0.9959 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K07 mock treatment 25480.0 -10400.0 -0.6 37640.0 -15000.0 -1.13 -1.2262 -0.9564 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K08 mock treatment 26480.0 -9390.0 -0.54 53120.0 527.0 0.04 -0.3567 -0.6536 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K09 mock treatment 24160.0 -11700.0 -0.68 46600.0 -5990.0 -0.45 -0.8007 -0.9808 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K10 mock treatment 25280.0 -10600.0 -0.61 41320.0 -11300.0 -0.85 -1.0374 -0.9869 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K11 mock treatment 21280.0 -14600.0 -0.85 39600.0 -13000.0 -0.98 -1.2934 -0.9972 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K12 mock treatment 22880.0 -13000.0 -0.75 46040.0 -6550.0 -0.5 -0.8831 -0.9795 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K13 mock treatment 24560.0 -11300.0 -0.66 51880.0 -713.0 -0.05 -0.5017 -0.7628 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K14 mock treatment 29120.0 -6750.0 -0.39 49040.0 -3550.0 -0.27 -0.4669 -0.9833 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K15 mock treatment 38200.0 2330.0 0.13 51200.0 -1390.0 -0.11 0.0207 0.1209 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K16 mock treatment 43680.0 7810.0 0.45 52160.0 -433.0 -0.03 0.2966 0.6541 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K17 mock treatment 50680.0 14800.0 0.86 59240.0 6650.0 0.5 0.9623 0.9677 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K18 mock treatment 53520.0 17600.0 1.02 54360.0 1770.0 0.13 0.8174 0.7928 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K19 mock treatment 46520.0 10600.0 0.62 51520.0 -1070.0 -0.08 0.3787 0.6087 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K20 mock treatment 55080.0 19200.0 1.11 49760.0 -2830.0 -0.21 0.6351 0.5605 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K21 mock treatment 43400.0 7530.0 0.44 49560.0 -3030.0 -0.23 0.1459 0.2962 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K22 mock treatment 40520.0 4650.0 0.27 48800.0 -3790.0 -0.29 -0.0127 -0.0324 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K23 mock treatment 43400.0 7530.0 0.44 52560.0 -33.5 0.0 0.3065 0.703 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base K24 mock treatment 41920.0 6050.0 0.35 50760.0 -1830.0 -0.14 0.1495 0.3969 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L01 mock treatment 7960.0 -27900.0 -1.62 45600.0 -6990.0 -0.53 -1.5179 -0.892 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L02 mock treatment 22680.0 -13200.0 -0.76 44040.0 -8550.0 -0.65 -0.9984 -0.9966 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L03 mock treatment 16240.0 -19600.0 -1.14 50320.0 -2270.0 -0.17 -0.9261 -0.8049 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L04 mock treatment 11080.0 -24800.0 -1.44 37320.0 -15300.0 -1.16 -1.8333 -0.9942 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L05 mock treatment 18360.0 -17500.0 -1.01 33960.0 -18600.0 -1.41 -1.7149 -0.987 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L06 mock treatment 24800.0 -11100.0 -0.64 44480.0 -8110.0 -0.61 -0.888 -0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L07 mock treatment 27920.0 -7950.0 -0.46 50640.0 -1950.0 -0.15 -0.4304 -0.8893 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L08 mock treatment 31920.0 -3950.0 -0.23 52200.0 -393.0 -0.03 -0.1831 -0.7924 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L09 mock treatment 29040.0 -6830.0 -0.4 49640.0 -2950.0 -0.22 -0.4381 -0.9634 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L10 mock treatment 25880.0 -9990.0 -0.58 41120.0 -11500.0 -0.87 -1.0236 -0.9806 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L11 mock treatment 24040.0 -11800.0 -0.69 44000.0 -8590.0 -0.65 -0.9448 -0.9997 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L12 mock treatment 23880.0 -12000.0 -0.69 53760.0 1170.0 0.09 -0.429 -0.6123 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L13 mock treatment 29480.0 -6390.0 -0.37 52240.0 -353.0 -0.03 -0.2809 -0.7562 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L14 mock treatment 37720.0 1850.0 0.11 55920.0 3330.0 0.25 0.2536 0.9272 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L15 mock treatment 45840.0 9970.0 0.58 63360.0 10800.0 0.81 0.9845 0.9857 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L16 mock treatment 43960.0 8090.0 0.47 65120.0 12500.0 0.95 1.0017 0.9472 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L17 mock treatment 48600.0 12700.0 0.74 60720.0 8130.0 0.62 0.9563 0.9959 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L18 mock treatment 57400.0 21500.0 1.25 54880.0 2290.0 0.17 1.0042 0.7976 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L19 mock treatment 53120.0 17200.0 1.0 53240.0 647.0 0.05 0.7411 0.7409 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L20 mock treatment 52080.0 16200.0 0.94 61240.0 8650.0 0.65 1.1267 0.9844 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L21 mock treatment 51040.0 15200.0 0.88 56040.0 3450.0 0.26 0.8058 0.8791 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L22 mock treatment 48400.0 12500.0 0.73 61040.0 8450.0 0.64 0.9652 0.998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L23 mock treatment 46080.0 10200.0 0.59 56960.0 4370.0 0.33 0.6518 0.9622 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base L24 mock treatment 47080.0 11200.0 0.65 63480.0 10900.0 0.82 1.0418 0.993 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M01 mock treatment 22840.0 -13000.0 -0.76 52280.0 -313.0 -0.02 -0.5508 -0.729 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M02 mock treatment 31880.0 -3990.0 -0.23 50760.0 -1830.0 -0.14 -0.2618 -0.9701 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M03 mock treatment 41560.0 5690.0 0.33 50360.0 -2230.0 -0.17 0.1134 0.3062 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M04 mock treatment 13560.0 -22300.0 -1.29 35680.0 -16900.0 -1.28 -1.8195 -1.0 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M05 mock treatment 20360.0 -15500.0 -0.9 34760.0 -17800.0 -1.35 -1.5901 -0.9805 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M06 mock treatment 21680.0 -14200.0 -0.82 47720.0 -4870.0 -0.37 -0.8424 -0.9346 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M07 mock treatment 29880.0 -5990.0 -0.35 54800.0 2210.0 0.17 -0.1275 -0.3308 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M08 mock treatment 30280.0 -5590.0 -0.32 52520.0 -73.5 -0.01 -0.2331 -0.7191 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M09 mock treatment 24640.0 -11200.0 -0.65 48120.0 -4470.0 -0.34 -0.6997 -0.9536 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M10 mock treatment 27240.0 -8630.0 -0.5 44320.0 -8270.0 -0.63 -0.7966 -0.9938 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M11 mock treatment 24360.0 -11500.0 -0.67 49280.0 -3310.0 -0.25 -0.6491 -0.9107 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M12 mock treatment 26400.0 -9470.0 -0.55 44080.0 -8510.0 -0.64 -0.8438 -0.9968 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M13 mock treatment 29760.0 -6110.0 -0.35 55640.0 3050.0 0.23 -0.0874 -0.2069 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M14 mock treatment 43680.0 7810.0 0.45 61640.0 9050.0 0.68 0.804 0.9797 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M15 mock treatment 52640.0 16800.0 0.97 53840.0 1250.0 0.09 0.7536 0.7722 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M16 mock treatment 58440.0 22600.0 1.31 52080.0 -513.0 -0.04 0.897 0.6858 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M17 mock treatment 62800.0 26900.0 1.56 49040.0 -3550.0 -0.27 0.9129 0.5767 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M18 mock treatment 63040.0 27200.0 1.57 60880.0 8290.0 0.63 1.5564 0.9186 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M19 mock treatment 53920.0 18000.0 1.05 55400.0 2810.0 0.21 0.8895 0.8337 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M20 mock treatment 50640.0 14800.0 0.86 56280.0 3690.0 0.28 0.8022 0.8915 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M21 mock treatment 44840.0 8970.0 0.52 52320.0 -273.0 -0.02 0.3527 0.6784 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M22 mock treatment 49880.0 14000.0 0.81 59560.0 6970.0 0.53 0.9466 0.9782 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M23 mock treatment 46600.0 10700.0 0.62 55960.0 3370.0 0.25 0.6196 0.9225 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base M24 mock treatment 46520.0 10600.0 0.62 56480.0 3890.0 0.29 0.6441 0.9426 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N01 mock treatment 21320.0 -14600.0 -0.84 53840.0 1250.0 0.09 -0.5296 -0.6241 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N02 mock treatment 25440.0 -10400.0 -0.6 43200.0 -9390.0 -0.71 -0.9303 -0.9967 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N03 mock treatment 24720.0 -11200.0 -0.65 47360.0 -5230.0 -0.4 -0.7371 -0.9724 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N04 mock treatment 10800.0 -25100.0 -1.45 33840.0 -18800.0 -1.42 -2.031 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N05 mock treatment 18960.0 -16900.0 -0.98 37560.0 -15000.0 -1.14 -1.4976 -0.9972 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N06 mock treatment 26440.0 -9430.0 -0.55 44440.0 -8150.0 -0.62 -0.8229 -0.9982 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N07 mock treatment 28880.0 -6990.0 -0.41 54360.0 1770.0 0.13 -0.192 -0.4499 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N08 mock treatment 27360.0 -8510.0 -0.49 53280.0 687.0 0.05 -0.3121 -0.6291 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N09 mock treatment 26320.0 -9550.0 -0.55 45080.0 -7510.0 -0.57 -0.7936 -0.9999 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N10 mock treatment 23160.0 -12700.0 -0.74 40640.0 -12000.0 -0.9 -1.1607 -0.9948 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N11 mock treatment 24040.0 -11800.0 -0.69 45600.0 -6990.0 -0.53 -0.8592 -0.9918 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N12 mock treatment 25680.0 -10200.0 -0.59 50040.0 -2550.0 -0.19 -0.5543 -0.892 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N13 mock treatment 33760.0 -2110.0 -0.12 57640.0 5050.0 0.38 0.1835 0.4574 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N14 mock treatment 46520.0 10600.0 0.62 52080.0 -513.0 -0.04 0.4086 0.6612 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N15 mock treatment 49640.0 13800.0 0.8 55040.0 2450.0 0.19 0.6949 0.8487 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N16 mock treatment 54400.0 18500.0 1.07 52760.0 167.0 0.01 0.7679 0.7154 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N17 mock treatment 49040.0 13200.0 0.76 55840.0 3250.0 0.25 0.7131 0.8899 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N18 mock treatment 51880.0 16000.0 0.93 51240.0 -1350.0 -0.1 0.5833 0.6252 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N19 mock treatment 54360.0 18500.0 1.07 55240.0 2650.0 0.2 0.899 0.8251 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N20 mock treatment 47600.0 11700.0 0.68 55680.0 3090.0 0.23 0.6456 0.8986 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N21 mock treatment 43320.0 7450.0 0.43 54800.0 2210.0 0.17 0.4231 0.9147 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N22 mock treatment 46440.0 10600.0 0.61 53840.0 1250.0 0.09 0.4996 0.8066 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N23 mock treatment 47520.0 11600.0 0.67 59160.0 6570.0 0.5 0.8286 0.9887 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base N24 mock treatment 45480.0 9610.0 0.56 51480.0 -1110.0 -0.08 0.3339 0.5933 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O01 mock treatment 32840.0 -3030.0 -0.18 48920.0 -3670.0 -0.28 -0.3209 -0.9756 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O02 mock treatment 34760.0 -1110.0 -0.06 49840.0 -2750.0 -0.21 -0.193 -0.8847 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O03 mock treatment 35080.0 -795.0 -0.05 49680.0 -2910.0 -0.22 -0.1885 -0.8367 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O04 mock treatment 14080.0 -21800.0 -1.26 41000.0 -11600.0 -0.88 -1.5134 -0.9842 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O05 mock treatment 22680.0 -13200.0 -0.76 39280.0 -13300.0 -1.01 -1.2532 -0.9907 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O06 mock treatment 27600.0 -8270.0 -0.48 62040.0 9450.0 0.72 0.1666 0.1935 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O07 mock treatment 32720.0 -3150.0 -0.18 60320.0 7730.0 0.58 0.2843 0.464 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O08 mock treatment 32560.0 -3310.0 -0.19 62000.0 9410.0 0.71 0.3677 0.4986 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O09 mock treatment 25680.0 -10200.0 -0.59 46560.0 -6030.0 -0.46 -0.7406 -0.9919 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O10 mock treatment 22680.0 -13200.0 -0.76 48120.0 -4470.0 -0.34 -0.78 -0.9329 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O11 mock treatment 22240.0 -13600.0 -0.79 49440.0 -3150.0 -0.24 -0.7274 -0.8814 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O12 mock treatment 27280.0 -8590.0 -0.5 53960.0 1370.0 0.1 -0.279 -0.5485 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O13 mock treatment 34040.0 -1830.0 -0.11 64440.0 11800.0 0.9 0.5589 0.619 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O14 mock treatment 39960.0 4090.0 0.24 61520.0 8930.0 0.68 0.6452 0.9011 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O15 mock treatment 54320.0 18400.0 1.07 64280.0 11700.0 0.88 1.3812 0.9956 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O16 mock treatment 58920.0 23000.0 1.34 59240.0 6650.0 0.5 1.2999 0.911 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O17 mock treatment 62480.0 26600.0 1.54 65920.0 13300.0 1.01 1.8033 0.9789 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O18 mock treatment 53480.0 17600.0 1.02 59200.0 6610.0 0.5 1.0749 0.9462 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O19 mock treatment 53680.0 17800.0 1.03 58360.0 5770.0 0.44 1.0381 0.9268 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O20 mock treatment 51080.0 15200.0 0.88 64960.0 12400.0 0.94 1.2848 0.9995 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O21 mock treatment 50000.0 14100.0 0.82 58800.0 6210.0 0.47 0.9109 0.9653 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O22 mock treatment 53400.0 17500.0 1.02 58120.0 5530.0 0.42 1.0138 0.9232 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O23 mock treatment 49880.0 14000.0 0.81 53280.0 687.0 0.05 0.6105 0.7509 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base O24 mock treatment 52480.0 16600.0 0.96 61560.0 8970.0 0.68 1.1602 0.9854 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P01 mock treatment 43200.0 7330.0 0.42 58400.0 5810.0 0.44 0.6109 0.9998 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P02 mock treatment 37840.0 1970.0 0.11 57200.0 4610.0 0.35 0.3271 0.8917 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P03 mock treatment 24920.0 -11000.0 -0.63 42640.0 -9950.0 -0.75 -0.9815 -0.9964 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P04 mock treatment 16400.0 -19500.0 -1.13 32480.0 -20100.0 -1.52 -1.8744 -0.9891 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P05 mock treatment 18280.0 -17600.0 -1.02 41360.0 -11200.0 -0.85 -1.3221 -0.9959 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P06 mock treatment 25600.0 -10300.0 -0.6 57960.0 5370.0 0.41 -0.1337 -0.1855 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P07 mock treatment 28160.0 -7710.0 -0.45 48920.0 -3670.0 -0.28 -0.5127 -0.9739 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P08 mock treatment 28320.0 -7550.0 -0.44 54640.0 2050.0 0.15 -0.2 -0.4307 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P09 mock treatment 20960.0 -14900.0 -0.86 41840.0 -10800.0 -0.81 -1.1866 -0.9996 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P10 mock treatment 21840.0 -14000.0 -0.81 46400.0 -6190.0 -0.47 -0.9065 -0.9658 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P11 mock treatment 21640.0 -14200.0 -0.82 47960.0 -4630.0 -0.35 -0.8312 -0.9274 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P12 mock treatment 26880.0 -8990.0 -0.52 47360.0 -5230.0 -0.4 -0.6486 -0.9908 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P13 mock treatment 29280.0 -6590.0 -0.38 55560.0 2970.0 0.22 -0.1114 -0.2513 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P14 mock treatment 48440.0 12600.0 0.73 60960.0 8370.0 0.63 0.9626 0.9976 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P15 mock treatment 52720.0 16800.0 0.98 57520.0 4930.0 0.37 0.9538 0.9129 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P16 mock treatment 58320.0 22400.0 1.3 50000.0 -2590.0 -0.2 0.7807 0.5936 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P17 mock treatment 55840.0 20000.0 1.16 51960.0 -633.0 -0.05 0.784 0.6772 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P18 mock treatment 54200.0 18300.0 1.06 59960.0 7370.0 0.56 1.145 0.9548 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P19 mock treatment 48160.0 12300.0 0.71 62560.0 9970.0 0.75 1.0368 0.9996 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P20 mock treatment 42960.0 7090.0 0.41 55480.0 2890.0 0.22 0.4448 0.9564 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P21 mock treatment 46480.0 10600.0 0.61 60200.0 7610.0 0.58 0.8416 0.9995 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P22 mock treatment 48800.0 12900.0 0.75 55120.0 2530.0 0.19 0.6648 0.8601 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P23 mock treatment 47360.0 11500.0 0.67 57440.0 4850.0 0.37 0.7299 0.9606 1009.0005 LuxReporter(1009.0005) cAMPSignalingReporter 1009.0005.Base P24 mock treatment 46800.0 10900.0 0.63 56000.0 3410.0 0.26 0.6299 0.9216