ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A01 mock treatment 4760.0 2340.0 1.01 4560.0 1590.0 0.73 1.23 0.9877 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A02 mock treatment 4240.0 1820.0 0.78 4960.0 1990.0 0.92 1.202 0.997 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A03 compound treatment 6520.0 4100.0 1.76 7680.0 4710.0 2.17 2.7797 0.9948 3001896 Bio2_000321 C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@@]24[C@@H](/C=C/C[C@H](C)C(=O)[C@@](C)(O)/C=C/[C@H]4OC(=O)C)[C@H](O)C1=C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A04 mock treatment 3280.0 862.0 0.37 4720.0 1750.0 0.81 0.832 0.9379 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A05 compound treatment 3600.0 1180.0 0.51 4280.0 1310.0 0.6 0.7862 0.9964 236 Bio2_000322 SC(=S)OC1CC2CC1C3CCCC23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A06 mock treatment 3520.0 1100.0 0.47 4640.0 1670.0 0.77 0.879 0.9729 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A07 compound treatment 3000.0 582.0 0.25 2560.0 -407.0 -0.19 0.0445 0.1425 159 Bio2_000323 COc1c(C=O)c(O)cc2C(=O)c3ccccc3C(=O)c12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A08 mock treatment 2760.0 342.0 0.15 3240.0 273.0 0.13 0.1927 0.9968 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A09 compound treatment 2000.0 -418.0 -0.18 3360.0 393.0 0.18 5.0E-4 0.0021 2370 Bio2_000324 OCc1ccc(o1)c2nn(Cc3ccccc3)c4ccccc24 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A10 mock treatment 2720.0 302.0 0.13 3080.0 113.0 0.05 0.1285 0.9188 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A11 compound treatment 2280.0 -138.0 -0.06 3000.0 32.7 0.02 -0.0314 -0.512 251 Bio2_000325 Nc1ncnc2n(cnc12)C3(CO)OC(=C)C(O)C3O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A12 mock treatment 2200.0 -218.0 -0.09 3040.0 72.7 0.03 -0.0427 -0.4287 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A13 compound treatment 2200.0 -218.0 -0.09 3160.0 193.0 0.09 -0.0037 -0.0284 3001897 Bio2_000326 OC[C@H]1*C[C@@H](O)[C@@H](O)[C@@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A14 mock treatment 2680.0 262.0 0.11 3800.0 833.0 0.38 0.3504 0.878 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A15 compound treatment 2400.0 -18.0 -0.01 3360.0 393.0 0.18 0.1222 0.6761 1907766 Bio2_000327 OC[C@H]1*C[C@H](O)[C@@H](O)[C@@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A16 mock treatment 2680.0 262.0 0.11 3160.0 193.0 0.09 0.1423 0.9929 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A17 compound treatment 3280.0 862.0 0.37 4360.0 1390.0 0.64 0.7149 0.9662 3103895 Bio2_000328 C[C@@H]1CC2C3CCC4=CC(=O)C=CC4(C)[C@@]3(F)[C@@H](O)CC2(C)[C@@]1(O)C(=O)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A18 mock treatment 2920.0 502.0 0.22 3280.0 313.0 0.14 0.2543 0.9805 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A19 compound treatment 3600.0 1180.0 0.51 4040.0 1070.0 0.49 0.7082 0.9999 3103896 Bio2_000329 CCCC(=O)Nc1ncnc2n(cnc12)C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3OC(=O)CCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A20 mock treatment 3000.0 582.0 0.25 3480.0 513.0 0.24 0.3437 0.9996 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A21 compound treatment 3320.0 902.0 0.39 3600.0 633.0 0.29 0.48 0.9899 3001899 Bio2_000330 CCCC(=O)Nc1nc2n(cnc2c(=O)[nH]1)C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3OC(=O)CCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A22 mock treatment 2560.0 142.0 0.06 3240.0 273.0 0.13 0.1318 0.9453 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A23 mock treatment 3640.0 1220.0 0.53 4000.0 1030.0 0.47 0.7074 0.9987 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 A24 mock treatment 120.0 -2300.0 -0.99 160.0 -2810.0 -1.29 -1.6116 -0.9913 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B01 mock treatment 5160.0 2740.0 1.18 4040.0 1070.0 0.49 1.1826 0.9252 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B02 mock treatment 3640.0 1220.0 0.53 3640.0 673.0 0.31 0.5903 0.9681 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B03 compound treatment 7560.0 5140.0 2.21 10360.0 7390.0 3.4 3.9673 0.9783 440 Bio2_000331 COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3cccs3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B04 mock treatment 3040.0 622.0 0.27 4120.0 1150.0 0.53 0.5639 0.9499 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B05 compound treatment 2840.0 422.0 0.18 3040.0 72.7 0.03 0.152 0.8235 442 Bio2_000332 CCCCCCCCCCCCCCCCCCc1ccc(cc1)C(=O)/C=C/C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B06 mock treatment 3360.0 942.0 0.41 360.0 -2610.0 -1.2 -0.5613 -0.4435 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B07 compound treatment 1120.0 -1300.0 -0.56 1240.0 -1730.0 -0.79 -0.9564 -0.9851 3103897 Bio2_000333 C[C@@H](CC(O)[C@H]1OC2CC[C@@]3(CC[C@H](O3)/C=C/[C@@H](C)[C@@H]4CC(=C[C@@]5(O[C@H](C[C@@](C)(O)C(=O)O)CCC5O)O4)C)OC2[C@H](O)C1=C)C6O[C@@]7(CCCCO7)CC[C@H]6C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B08 mock treatment 2960.0 542.0 0.23 2200.0 -767.0 -0.35 -0.0847 -0.2002 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B09 compound treatment 120.0 -2300.0 -0.99 120.0 -2850.0 -1.31 -1.6246 -0.9904 3104621 Bio2_000334 CC[C@H]/1CC[C@H]2O[C@@]3(CC[C@@H](C)[C@@H](C[C@H](C)O)O3)[C@H](C)[C@@H](OC(=O)/C=C/[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@](C)(O)[C@H](O)[C@@H](C)C\C=C\C=C1)[C@H]2C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B10 mock treatment 2960.0 542.0 0.23 2960.0 -7.32 0.0 0.1624 0.6968 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B11 compound treatment 1160.0 -1260.0 -0.54 1800.0 -1170.0 -0.54 -0.7621 -1.0 324 Bio2_000335 Cn1cnc2c(NCc3ccccc3)nc(NCCO)nc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B12 mock treatment 2240.0 -178.0 -0.08 3520.0 553.0 0.25 0.1256 0.4731 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B13 compound treatment 840.0 -1580.0 -0.68 1240.0 -1730.0 -0.79 -1.0415 -0.9969 3103898 Bio2_000336 CC1OC(OC2CC(O)C3(CO)C4[C@H](O)CC5(C)C(CCC5(O)C4CCC3(O)C2)C6=CC(=O)OC6)C(O)C(O)C1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B14 mock treatment 2520.0 102.0 0.04 2880.0 -87.3 -0.04 0.0026 0.044 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B15 compound treatment 1080.0 -1340.0 -0.58 1440.0 -1530.0 -0.7 -0.9035 -0.9951 444 Bio2_000337 COC(=O)C1=C(C)NC(=C(C1C)C(=O)OCCSc2ccccc2)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B16 mock treatment 2640.0 222.0 0.1 3120.0 153.0 0.07 0.1171 0.9886 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B17 compound treatment 1240.0 -1180.0 -0.51 1560.0 -1410.0 -0.65 -0.8158 -0.9927 453 Bio2_000338 COc1cccc(c1N)c2cc(=O)c3ccccc3o2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B18 mock treatment 2160.0 -258.0 -0.11 3080.0 113.0 0.05 -0.0418 -0.3416 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B19 compound treatment 2040.0 -378.0 -0.16 2360.0 -607.0 -0.28 -0.3124 -0.9669 1907767 Bio2_000339 CN(C)c1ccc(/C=C/2\C(=O)Nc3ccccc23)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B20 mock treatment 2120.0 -298.0 -0.13 2960.0 -7.32 0.0 -0.093 -0.7254 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B21 compound treatment 2400.0 -18.0 -0.01 3920.0 953.0 0.44 0.3043 0.6945 387 Bio2_000340 CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CC(C)C)C(C)C)C(C)C)[C@@H](O)CC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B22 mock treatment 3240.0 822.0 0.35 3040.0 72.7 0.03 0.2736 0.7705 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B23 mock treatment 3520.0 1100.0 0.47 2720.0 -247.0 -0.11 0.2547 0.5226 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 B24 mock treatment 80.0 -2340.0 -1.01 160.0 -2810.0 -1.29 -1.6238 -0.9924 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C01 mock treatment 4120.0 1700.0 0.73 3560.0 593.0 0.27 0.7103 0.9094 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C02 mock treatment 3440.0 1020.0 0.44 4560.0 1590.0 0.73 0.8286 0.9702 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C03 compound treatment 2360.0 -58.0 -0.02 3200.0 233.0 0.11 0.058 0.528 1907768 Bio2_000341 [O-][N+](=O)c1ccc(Cl)c(c1)C(=O)Nc2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C04 mock treatment 3280.0 862.0 0.37 4520.0 1550.0 0.71 0.767 0.9534 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C05 compound treatment 1960.0 -458.0 -0.2 3120.0 153.0 0.07 -0.0896 -0.4287 1907769 Bio2_000342 *C1CCc2cc(O)c(O)cc2C1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C06 mock treatment 2640.0 222.0 0.1 3480.0 513.0 0.24 0.2342 0.9208 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C07 compound treatment 2240.0 -178.0 -0.08 920.0 -2050.0 -0.94 -0.7198 -0.7621 2098 Bio2_000343 CC(C)c1cccc(=O)c(O)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C08 mock treatment 2680.0 262.0 0.11 3360.0 393.0 0.18 0.2073 0.9742 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C09 compound treatment 40.0 -2380.0 -1.02 120.0 -2850.0 -1.31 -1.6489 -0.9925 411 Bio2_000344 [I+]1c2ccccc2-c3ccccc13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C10 mock treatment 2120.0 -298.0 -0.13 3720.0 753.0 0.35 0.1541 0.4175 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C11 compound treatment 120.0 -2300.0 -0.99 200.0 -2770.0 -1.27 -1.5986 -0.9922 1961 Bio2_000345 CC(C)(C)c1cc(O)c(cc1O)C(C)(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C12 mock treatment 2320.0 -98.0 -0.04 4120.0 1150.0 0.53 0.345 0.6488 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C13 compound treatment 40.0 -2380.0 -1.02 80.0 -2890.0 -1.33 -1.6619 -0.9917 3103899 Bio2_000346 COc1cccc2C(=O)C3C(C(=C4[C@H](C[C@@](O)(CC4=C3O)C(=O)CO)OC5CC(N)C(O)C(C)O5)O)C(=O)c12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C14 mock treatment 2320.0 -98.0 -0.04 3240.0 273.0 0.13 0.0588 0.4448 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C15 compound treatment 200.0 -2220.0 -0.95 440.0 -2530.0 -1.16 -1.4962 -0.9952 3000146 Bio2_000347 OC[C@H]1O[C@H](C(O)[C@H]1O)n2cnc3cc(Cl)c(Cl)cc23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C16 mock treatment 2320.0 -98.0 -0.04 3880.0 913.0 0.42 0.2669 0.6329 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C17 compound treatment 2000.0 -418.0 -0.18 2840.0 -127.0 -0.06 -0.1685 -0.8913 3103900 Bio2_000348 OC(=O)c1ccc(cc1)C2=C3C=CC4=[N+]3[Mn+3]5([N+]6=C7C=CC6=C(c8ccc2n85)c9ccc(cc9)C(=O)O)n%10c(=C4c%11ccc(cc%11)C(=O)O)ccc%10=C7c%12ccc(cc%12)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C18 mock treatment 2480.0 62.0 0.03 2880.0 -87.3 -0.04 -0.0095 -0.1981 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C19 compound treatment 1960.0 -458.0 -0.2 2600.0 -367.0 -0.17 -0.2587 -0.9971 3002358 Bio2_000349 COc1cc2CCN(C)[C@@H]3Cc4ccc(OC(=O)c5ccc(cc5)[N+](=O)[O-])c(Oc6ccc(C[C@@H]7N(C)CCc8ccc(Oc(c1OC)c32)cc78)cc6)c4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C20 mock treatment 2720.0 302.0 0.13 3360.0 393.0 0.18 0.2195 0.9869 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C21 compound treatment 2360.0 -58.0 -0.02 3640.0 673.0 0.31 0.2011 0.6479 3002360 Bio2_000350 *[C@H]1O[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCCC(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C22 mock treatment 2800.0 382.0 0.16 3160.0 193.0 0.09 0.1788 0.958 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C23 mock treatment 3440.0 1020.0 0.44 3400.0 433.0 0.2 0.4515 0.9358 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 C24 mock treatment 120.0 -2300.0 -0.99 80.0 -2890.0 -1.33 -1.6376 -0.9894 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D01 mock treatment 3880.0 1460.0 0.63 3800.0 833.0 0.38 0.7153 0.9717 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D02 mock treatment 3240.0 822.0 0.35 4560.0 1590.0 0.73 0.7678 0.9442 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D03 compound treatment 1280.0 -1140.0 -0.49 2560.0 -407.0 -0.19 -0.4785 -0.9131 384 Bio2_000351 O=c1[nH]c2ccccc2c3ccccc13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D04 mock treatment 2240.0 -178.0 -0.08 3760.0 793.0 0.36 0.2036 0.5466 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D05 compound treatment 4480.0 2060.0 0.89 5640.0 2670.0 1.23 1.496 0.9872 290 Bio2_000352 CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)C)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D06 mock treatment 2160.0 -258.0 -0.11 3640.0 673.0 0.31 0.1402 0.4268 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D07 compound treatment 240.0 -2180.0 -0.94 400.0 -2570.0 -1.18 -1.4971 -0.9934 455 Bio2_000353 Cc1ccc(cc1)C(=O)Cn2c3CCCCc3sc2=N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D08 mock treatment 3000.0 582.0 0.25 3480.0 513.0 0.24 0.3437 0.9996 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D09 compound treatment 1600.0 -818.0 -0.35 1640.0 -1330.0 -0.61 -0.6803 -0.9657 1907770 Bio2_000354 Clc1ccc(cc1)c2nc3sccn3c2/C=N/OCc4ccc(Cl)c(Cl)c4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D10 mock treatment 2560.0 142.0 0.06 2800.0 -167.0 -0.08 -0.0112 -0.1143 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D11 compound treatment 2360.0 -58.0 -0.02 2360.0 -607.0 -0.28 -0.2151 -0.7672 347 Bio2_000355 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3ccccn3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D12 mock treatment 2600.0 182.0 0.08 2760.0 -207.0 -0.1 -0.0121 -0.0979 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D13 compound treatment 1440.0 -978.0 -0.42 1880.0 -1090.0 -0.5 -0.651 -0.9963 1907771 Bio2_000356 CC1[C@@H]2NC[C@@H](C)C[C@H]2O[C@@]31CC[C@H]4[C@@H]5CC=C6C[C@@H](O)CC[C@]6(C)[C@H]5CC4=C3C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D14 mock treatment 2320.0 -98.0 -0.04 2920.0 -47.3 -0.02 -0.0452 -0.9526 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D15 compound treatment 1840.0 -578.0 -0.25 2680.0 -287.0 -0.13 -0.2692 -0.9562 275745 Bio2_000357 Cc1ccc(cc1)c2nn(c3ncnc(N)c23)C(C)(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D16 mock treatment 1880.0 -538.0 -0.23 2400.0 -567.0 -0.26 -0.3481 -0.9982 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D17 compound treatment 1720.0 -698.0 -0.3 2160.0 -807.0 -0.37 -0.4748 -0.9945 349 Bio2_000358 COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4ccco4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D18 mock treatment 1960.0 -458.0 -0.2 3000.0 32.7 0.02 -0.1287 -0.6513 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D19 compound treatment 1400.0 -1020.0 -0.44 1840.0 -1130.0 -0.52 -0.6761 -0.9965 244 Bio2_000359 CC[N+](C)(CC)CCC[n+]1c(c2ccccc2)c3cc(N)ccc3c4ccc(N)cc14 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D20 mock treatment 2680.0 262.0 0.11 3240.0 273.0 0.13 0.1683 0.9986 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D21 compound treatment 3040.0 622.0 0.27 3240.0 273.0 0.13 0.2778 0.9404 3002368 Bio2_000360 CC(C)NC[C@H](O)COc1cccc2ccccc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D22 mock treatment 3160.0 742.0 0.32 2800.0 -167.0 -0.08 0.1712 0.5217 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D23 mock treatment 2560.0 142.0 0.06 2840.0 -127.0 -0.06 0.0018 0.021 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 D24 mock treatment 160.0 -2260.0 -0.97 120.0 -2850.0 -1.31 -1.6125 -0.9892 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E01 mock treatment 3440.0 1020.0 0.44 4320.0 1350.0 0.62 0.7506 0.9855 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E02 mock treatment 2960.0 542.0 0.23 3600.0 633.0 0.29 0.3705 0.994 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E03 compound treatment 1840.0 -578.0 -0.25 2640.0 -327.0 -0.15 -0.2822 -0.9711 413 Bio2_000361 CCCCCC[C@@H]([C@@H](C)O)n1cnc2c(N)ncnc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E04 mock treatment 2600.0 182.0 0.08 4920.0 1950.0 0.9 0.6902 0.7658 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E05 compound treatment 1640.0 -778.0 -0.33 4440.0 1470.0 0.68 0.2422 0.3207 1907772 Bio2_000362 CC(=O)[C@H]1[C@@H](CC2C3CC=C4C[C@@H](O)CCC4(C)C3CCC12C)C#N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E06 mock treatment 2080.0 -338.0 -0.15 5040.0 2070.0 0.95 0.5711 0.5924 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E07 compound treatment 1640.0 -778.0 -0.33 3240.0 273.0 0.13 -0.1479 -0.414 386 Bio2_000363 C[C@@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]2CC[C@@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E08 mock treatment 2000.0 -418.0 -0.18 3640.0 673.0 0.31 0.0916 0.256 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E09 compound treatment 840.0 -1580.0 -0.68 1560.0 -1410.0 -0.65 -0.9375 -0.9997 2080384 Bio2_000364 COc1cc(cc(OC)c1O)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](OC4OC5COC(C)OC5C(O)C4O)c6cc7OCOc7cc26 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E10 mock treatment 2280.0 -138.0 -0.06 3120.0 153.0 0.07 0.0077 0.0834 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E11 compound treatment 120.0 -2300.0 -0.99 80.0 -2890.0 -1.33 -1.6376 -0.9894 415 Bio2_000365 FC(F)(F)Oc1ccc(NN=C(C#N)C#N)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E12 mock treatment 2080.0 -338.0 -0.15 2600.0 -367.0 -0.17 -0.2222 -0.9972 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E13 compound treatment 2160.0 -258.0 -0.11 3280.0 313.0 0.14 0.0232 0.1277 3002452 Bio2_000366 CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E14 mock treatment 1920.0 -498.0 -0.21 2400.0 -567.0 -0.26 -0.3359 -0.9952 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E15 compound treatment 600.0 -1820.0 -0.78 720.0 -2250.0 -1.03 -1.2836 -0.9905 3104393 Bio2_000367 CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)/C(=C/C=C\[C@H](OC)[C@@H](OC(=O)N)/C(=C/[C@H](C)[C@H]1O)/C)/C)C2=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E16 mock treatment 1920.0 -498.0 -0.21 2560.0 -407.0 -0.19 -0.2839 -0.9978 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E17 compound treatment 1680.0 -738.0 -0.32 1880.0 -1090.0 -0.5 -0.578 -0.976 3103903 Bio2_000368 Cc1ccc(cc1)C2=CCc3cc(C)cc(C)c3C2=C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E18 mock treatment 2440.0 22.0 0.01 2760.0 -207.0 -0.1 -0.0607 -0.6339 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E19 compound treatment 80.0 -2340.0 -1.01 80.0 -2890.0 -1.33 -1.6498 -0.9906 576 Bio2_000369 Cn1cc(C2=C(C(=O)NC2=O)c3cn(CCCSC(=N)N)c4ccccc34)c5ccccc15 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E20 mock treatment 1960.0 -458.0 -0.2 3120.0 153.0 0.07 -0.0896 -0.4287 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E21 compound treatment 1960.0 -458.0 -0.2 2920.0 -47.3 -0.02 -0.1547 -0.7805 162 Bio2_000370 CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E22 mock treatment 2000.0 -418.0 -0.18 2840.0 -127.0 -0.06 -0.1685 -0.8913 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E23 mock treatment 3040.0 622.0 0.27 3040.0 72.7 0.03 0.2128 0.7893 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 E24 mock treatment 120.0 -2300.0 -0.99 40.0 -2930.0 -1.35 -1.6506 -0.9885 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F01 mock treatment 3360.0 942.0 0.41 3760.0 793.0 0.36 0.5442 0.9986 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F02 mock treatment 2680.0 262.0 0.11 3440.0 473.0 0.22 0.2334 0.9532 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F03 compound treatment 120.0 -2300.0 -0.99 80.0 -2890.0 -1.33 -1.6376 -0.9894 3002455 Bio2_000371 *[C@H]1O[C@H]([C@H](O)[C@@H]1NC(=O)C(N)Cc2ccccc2)n3cnc4c(ncnc34)N(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F04 mock treatment 2480.0 62.0 0.03 3120.0 153.0 0.07 0.0685 0.912 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F05 compound treatment 2120.0 -298.0 -0.13 2080.0 -887.0 -0.41 -0.3791 -0.8865 1907773 Bio2_000372 NC(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccc4OCOc4c3)c5ccccn5 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F06 mock treatment 2040.0 -378.0 -0.16 3520.0 553.0 0.25 0.0647 0.2146 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F07 compound treatment 280.0 -2140.0 -0.92 3400.0 433.0 0.2 -0.5095 -0.5416 1000035 Bio2_000373 O=C1c2ccccc2-c3n[nH]c4cccc1c34 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F08 mock treatment 840.0 -1580.0 -0.68 3120.0 153.0 0.07 -0.4302 -0.6306 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F09 compound treatment 840.0 -1580.0 -0.68 1320.0 -1650.0 -0.76 -1.0155 -0.9985 353 Bio2_000374 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F10 mock treatment 2560.0 142.0 0.06 2080.0 -887.0 -0.41 -0.2453 -0.5947 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F11 compound treatment 1240.0 -1180.0 -0.51 1720.0 -1250.0 -0.57 -0.7638 -0.9981 3104890 Bio2_000375 CO[C@@H]1CC(CC(C)[C@@H]2CC(=O)[C@H](C)/C=C(\C)/[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)/C=C/C=C/C=C(\C)/[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)OC)CC[C@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F12 mock treatment 1880.0 -538.0 -0.23 2480.0 -487.0 -0.22 -0.3221 -0.9999 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F13 compound treatment 2600.0 182.0 0.08 3120.0 153.0 0.07 0.105 0.9985 1907774 Bio2_000376 CC(C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F14 mock treatment 1600.0 -818.0 -0.35 2600.0 -367.0 -0.17 -0.3682 -0.9435 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F15 compound treatment 760.0 -1660.0 -0.71 1280.0 -1690.0 -0.78 -1.0528 -0.9991 285 Bio2_000377 O=C(NCCCCCCNC(=O)ON=C1CCCCC1)ON=C2CCCCC2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F16 mock treatment 2480.0 62.0 0.03 2600.0 -367.0 -0.17 -0.1006 -0.5883 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F17 compound treatment 2320.0 -98.0 -0.04 3120.0 153.0 0.07 0.0198 0.2421 151 Bio2_000378 CCCCCCCCCCCCCCCC(=O)C1=C(O)C(CO)OC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F18 mock treatment 2120.0 -298.0 -0.13 2360.0 -607.0 -0.28 -0.2881 -0.9376 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F19 compound treatment 200.0 -2220.0 -0.95 160.0 -2810.0 -1.29 -1.5873 -0.9889 291 Bio2_000379 CC[C@H](CO)Nc1nc(NCc2ccccc2)c3ncn(C(C)C)c3n1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F20 mock treatment 1920.0 -498.0 -0.21 2520.0 -447.0 -0.21 -0.2969 -0.9998 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F21 compound treatment 40.0 -2380.0 -1.02 40.0 -2930.0 -1.35 -1.675 -0.9908 320 Bio2_000380 CC(=O)c1c(O)c(C)c(O)c(Cc2c(O)c(C(=O)/C=C/c3ccccc3)c4OC(C)(C)C=Cc4c2O)c1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F22 mock treatment 2600.0 182.0 0.08 2880.0 -87.3 -0.04 0.0269 0.3063 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F23 mock treatment 2960.0 542.0 0.23 3600.0 633.0 0.29 0.3705 0.994 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 F24 mock treatment 80.0 -2340.0 -1.01 80.0 -2890.0 -1.33 -1.6498 -0.9906 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G01 mock treatment 2720.0 302.0 0.13 2280.0 -687.0 -0.32 -0.1316 -0.3853 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G02 mock treatment 2920.0 502.0 0.22 2360.0 -607.0 -0.28 -0.0448 -0.127 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G03 compound treatment 680.0 -1740.0 -0.75 720.0 -2250.0 -1.03 -1.2592 -0.9874 152 Bio2_000381 Cn1c2ccccc2c3c4C(=O)NCc4c5c6ccccc6n(CCC#N)c5c13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G04 mock treatment 2440.0 22.0 0.01 2760.0 -207.0 -0.1 -0.0607 -0.6339 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G05 compound treatment 1680.0 -738.0 -0.32 3360.0 393.0 0.18 -0.0968 -0.265 1298 Bio2_000382 CS(=O)(=O)Nc1ccc(cc1Oc2ccccc2)[N+](=O)[O-] 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G06 mock treatment 2280.0 -138.0 -0.06 3480.0 513.0 0.24 0.1247 0.513 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G07 compound treatment 80.0 -2340.0 -1.01 280.0 -2690.0 -1.24 -1.5848 -0.9948 414 Bio2_000383 CC1CNCCN1S(=O)(=O)c2cccc3cnccc23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G08 mock treatment 2040.0 -378.0 -0.16 3440.0 473.0 0.22 0.0387 0.1427 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G09 compound treatment 80.0 -2340.0 -1.01 240.0 -2730.0 -1.25 -1.5978 -0.994 607 Bio2_000384 Brc1ccc(/C=C/CNCCNS(=O)(=O)c2cccc3cnccc23)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G10 mock treatment 1760.0 -658.0 -0.28 3040.0 72.7 0.03 -0.1765 -0.6193 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G11 compound treatment 200.0 -2220.0 -0.95 640.0 -2330.0 -1.07 -1.4312 -0.9984 3002468 Bio2_000385 NCCNOc1cccc2cnccc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G12 mock treatment 1320.0 -1100.0 -0.47 3480.0 513.0 0.24 -0.1672 -0.3168 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G13 compound treatment 520.0 -1900.0 -0.82 960.0 -2010.0 -0.92 -1.2299 -0.9981 610 Bio2_000386 O=S(=O)(N1CCCNCC1)c2cccc3cnccc23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G14 mock treatment 2520.0 102.0 0.04 3400.0 433.0 0.2 0.1717 0.8427 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G15 compound treatment 1880.0 -538.0 -0.23 2360.0 -607.0 -0.28 -0.3611 -0.9956 609 Bio2_000387 NC(=N)NCCNS(=O)(=O)c1cccc2cnccc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G16 mock treatment 2120.0 -298.0 -0.13 3160.0 193.0 0.09 -0.028 -0.1796 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G17 compound treatment 1360.0 -1060.0 -0.46 1960.0 -1010.0 -0.46 -0.6493 -1.0 611 Bio2_000388 COCc1cc(O)c(O)c(O)c1c2c(O)c(O)c(O)cc2COC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G18 mock treatment 2120.0 -298.0 -0.13 2720.0 -247.0 -0.11 -0.171 -0.9982 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G19 compound treatment 2120.0 -298.0 -0.13 2520.0 -447.0 -0.21 -0.2361 -0.9741 465 Bio2_000389 NCCc1c[nH]cn1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G20 mock treatment 1600.0 -818.0 -0.35 2400.0 -567.0 -0.26 -0.4332 -0.9892 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G21 compound treatment 40.0 -2380.0 -1.02 120.0 -2850.0 -1.31 -1.6489 -0.9925 239 Bio2_000390 CC(=O)OCOC(c1ccc2ccccc2c1)P(=O)(OCOC(=O)C)OCOC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G22 mock treatment 3000.0 582.0 0.25 2760.0 -207.0 -0.1 0.1096 0.4091 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G23 mock treatment 2440.0 22.0 0.01 2840.0 -127.0 -0.06 -0.0347 -0.5854 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 G24 mock treatment 160.0 -2260.0 -0.97 80.0 -2890.0 -1.33 -1.6255 -0.9882 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H01 mock treatment 2800.0 382.0 0.16 2840.0 -127.0 -0.06 0.0748 0.4287 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H02 mock treatment 2360.0 -58.0 -0.02 3360.0 393.0 0.18 0.11 0.6036 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H03 compound treatment 40.0 -2380.0 -1.02 120.0 -2850.0 -1.31 -1.6489 -0.9925 3104891 Bio2_000391 CC(=O)OCOC(P(=O)OCOC(=O)C)c1cc(ccc1Oc2ccc(Br)cc2)[N+](=O)[O-] 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H04 mock treatment 2640.0 222.0 0.1 2640.0 -327.0 -0.15 -0.0389 -0.2184 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H05 compound treatment 1280.0 -1140.0 -0.49 2040.0 -927.0 -0.43 -0.6476 -0.9976 1907775 Bio2_000392 CS(=O)(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H06 mock treatment 2520.0 102.0 0.04 3120.0 153.0 0.07 0.0806 0.9743 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H07 compound treatment 1040.0 -1380.0 -0.59 1480.0 -1490.0 -0.68 -0.9027 -0.9975 457 Bio2_000393 Oc1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H08 mock treatment 2680.0 262.0 0.11 2480.0 -487.0 -0.22 -0.0788 -0.3141 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H09 compound treatment 600.0 -1820.0 -0.78 720.0 -2250.0 -1.03 -1.2836 -0.9905 1000586 Bio2_000394 O/N=C\1/C(=C\2/C(=O)Nc3ccccc23)/Nc4ccccc14 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H10 mock treatment 2080.0 -338.0 -0.15 2560.0 -407.0 -0.19 -0.2352 -0.9922 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H11 compound treatment 1160.0 -1260.0 -0.54 1440.0 -1530.0 -0.7 -0.8792 -0.9917 3104892 Bio2_000395 O=C/1Nc2ccccc2\C1=C/3\Nc4ccccc4C3=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H12 mock treatment 2200.0 -218.0 -0.09 2960.0 -7.32 0.0 -0.0687 -0.732 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H13 compound treatment 1880.0 -538.0 -0.23 1920.0 -1050.0 -0.48 -0.5041 -0.9436 429 Bio2_000396 NCCc1c[nH]c2ccc(O)cc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H14 mock treatment 1760.0 -658.0 -0.28 2680.0 -287.0 -0.13 -0.2935 -0.9398 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H15 compound treatment 920.0 -1500.0 -0.64 1160.0 -1810.0 -0.83 -1.0432 -0.9921 2269 Bio2_000397 Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H16 mock treatment 2120.0 -298.0 -0.13 2640.0 -327.0 -0.15 -0.1971 -0.9968 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H17 compound treatment 2080.0 -338.0 -0.15 1760.0 -1210.0 -0.56 -0.4953 -0.8632 2301 Bio2_000398 O=C1CCc2c(O1)ccc3ccccc23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H18 mock treatment 2120.0 -298.0 -0.13 2320.0 -647.0 -0.3 -0.3011 -0.9291 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H19 compound treatment 4160.0 1740.0 0.75 2920.0 -47.3 -0.02 0.5144 0.6863 650 Bio2_000399 CC(C)(C)n1nc(c2ccc(Cl)cc2)c3c(N)ncnc13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H20 mock treatment 2120.0 -298.0 -0.13 2840.0 -127.0 -0.06 -0.132 -0.937 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H21 compound treatment 1920.0 -498.0 -0.21 2560.0 -407.0 -0.19 -0.2839 -0.9978 648 Bio2_000400 Oc1cc(O)cc(/C=C/c2ccc(O)c(O)c2)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H22 mock treatment 2720.0 302.0 0.13 2880.0 -87.3 -0.04 0.0634 0.4667 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H23 mock treatment 3040.0 622.0 0.27 2600.0 -367.0 -0.17 0.0697 0.2204 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 H24 mock treatment 120.0 -2300.0 -0.99 120.0 -2850.0 -1.31 -1.6246 -0.9904 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I01 mock treatment 2920.0 502.0 0.22 2560.0 -407.0 -0.19 0.0202 0.0707 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I02 mock treatment 2840.0 422.0 0.18 3400.0 433.0 0.2 0.269 0.9989 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I03 compound treatment 120.0 -2300.0 -0.99 80.0 -2890.0 -1.33 -1.6376 -0.9894 369 Bio2_000401 CCOc1ccc(cc1)c2nc3cc(ccc3[nH]2)c4nc5cc(ccc5[nH]4)N6CCN(C)CC6 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I04 mock treatment 2440.0 22.0 0.01 4520.0 1550.0 0.71 0.5115 0.7164 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I05 compound treatment 2240.0 -178.0 -0.08 5240.0 2270.0 1.05 0.6848 0.6535 1001953 Bio2_000402 C/C=C/1\C2Cc3[nH]c(=O)ccc3C1(N)CC(=C2)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I06 mock treatment 2680.0 262.0 0.11 4720.0 1750.0 0.81 0.6495 0.7982 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I07 compound treatment 1720.0 -698.0 -0.3 3360.0 393.0 0.18 -0.0846 -0.2415 1907776 Bio2_000403 CC(C)[C@H](O)CCC(C)C1CCC2C3CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I08 mock treatment 2800.0 382.0 0.16 4000.0 1030.0 0.47 0.4519 0.8994 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I09 compound treatment 2000.0 -418.0 -0.18 2760.0 -207.0 -0.1 -0.1945 -0.956 3002553 Bio2_000404 C[C@@H]([C@@H](C)N1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I10 mock treatment 1560.0 -858.0 -0.37 2720.0 -247.0 -0.11 -0.3413 -0.884 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I11 compound treatment 1760.0 -658.0 -0.28 2360.0 -607.0 -0.28 -0.3976 -1.0 2797 Bio2_000405 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)O)c2c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I12 mock treatment 1880.0 -538.0 -0.23 2360.0 -607.0 -0.28 -0.3611 -0.9956 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I13 compound treatment 0.0 -2420.0 -1.04 80.0 -2890.0 -1.33 -1.6741 -0.9927 3002555 Bio2_000406 *CC[C@@H](C)C[C@H](C)C[C@H](C)C(=O)/C=C(\O)/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)C[C@@H]1CC[C@](C)(O1)[C@H]2CC[C@](C)(O2)[C@@H](C)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I14 mock treatment 2360.0 -58.0 -0.02 2320.0 -647.0 -0.3 -0.2281 -0.7637 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I15 compound treatment 1520.0 -898.0 -0.39 2320.0 -647.0 -0.3 -0.4836 -0.9917 1505 Bio2_000407 CC(C)Cn1c(=O)n(C)c(=O)c2[nH]cnc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I16 mock treatment 2600.0 182.0 0.08 2440.0 -527.0 -0.24 -0.1161 -0.4557 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I17 compound treatment 0.0 -2420.0 -1.04 40.0 -2930.0 -1.35 -1.6871 -0.9919 1054783 Bio2_000408 OCCSC1=C(SCCO)C(=O)c2ccccc2C1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I18 mock treatment 2040.0 -378.0 -0.16 2480.0 -487.0 -0.22 -0.2734 -0.9876 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I19 compound treatment 160.0 -2260.0 -0.97 240.0 -2730.0 -1.25 -1.5734 -0.992 422 Bio2_000409 Oc1cccc2C(=O)C=CC(=O)c12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I20 mock treatment 2600.0 182.0 0.08 2480.0 -487.0 -0.22 -0.1031 -0.4344 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I21 compound treatment 3720.0 1300.0 0.56 4160.0 1190.0 0.55 0.7837 0.9999 1907777 Bio2_000410 COC(=O)[C@@]1(O)C[C@@H]2O[C@@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I22 mock treatment 2840.0 422.0 0.18 2640.0 -327.0 -0.15 0.0219 0.0929 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I23 mock treatment 2680.0 262.0 0.11 3160.0 193.0 0.09 0.1423 0.9929 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 I24 mock treatment 120.0 -2300.0 -0.99 120.0 -2850.0 -1.31 -1.6246 -0.9904 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J01 mock treatment 2520.0 102.0 0.04 4240.0 1270.0 0.59 0.4448 0.758 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J02 mock treatment 2400.0 -18.0 -0.01 3520.0 553.0 0.25 0.1742 0.6852 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J03 compound treatment 1680.0 -738.0 -0.32 3200.0 233.0 0.11 -0.1488 -0.4442 837968 Bio2_000411 Nc1ncnc2n(cnc12)C3CCCO3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J04 mock treatment 2600.0 182.0 0.08 4000.0 1030.0 0.47 0.3911 0.8127 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J05 compound treatment 1680.0 -738.0 -0.32 5600.0 2630.0 1.21 0.6315 0.5046 790507 Bio2_000412 OC(=O)CN1C(=O)c2cccc3cccc(C1=O)c23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J06 mock treatment 1840.0 -578.0 -0.25 3040.0 72.7 0.03 -0.1522 -0.6066 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J07 compound treatment 80.0 -2340.0 -1.01 40.0 -2930.0 -1.35 -1.6628 -0.9897 3104896 Bio2_000413 CN[C@@H]1C[C@@]2(C)O[C@@H]([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J08 mock treatment 2440.0 22.0 0.01 2440.0 -527.0 -0.24 -0.1648 -0.679 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J09 compound treatment 2080.0 -338.0 -0.15 2840.0 -127.0 -0.06 -0.1442 -0.9201 197 Bio2_000414 O[C@@H]1CN2CCC[C@@H](O)[C@@H]2[C@@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J10 mock treatment 1560.0 -858.0 -0.37 3080.0 113.0 0.05 -0.2243 -0.6019 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J11 compound treatment 480.0 -1940.0 -0.83 1200.0 -1770.0 -0.81 -1.164 -0.9999 368 Bio2_000415 CC/C(=C(\c1ccccc1)/c2ccc(OCCN(C)C)cc2)/c3ccccc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J12 mock treatment 1920.0 -498.0 -0.21 2360.0 -607.0 -0.28 -0.3489 -0.9914 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J13 compound treatment 1920.0 -498.0 -0.21 2280.0 -687.0 -0.32 -0.3749 -0.982 1000045 Bio2_000416 CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c3ccccc3)C4[C@@]5(CO[C@@H]5C[C@H](O)[C@@]4(C)C1=O)OC(=O)C)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c6ccccc6)c7ccccc7 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J14 mock treatment 2160.0 -258.0 -0.11 2960.0 -7.32 0.0 -0.0809 -0.7282 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J15 compound treatment 1240.0 -1180.0 -0.51 1880.0 -1090.0 -0.5 -0.7118 -1.0 658 Bio2_000417 Clc1cc(Cl)cc(/C=C(\C#N)/c2cccnc2)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J16 mock treatment 1800.0 -618.0 -0.27 2640.0 -327.0 -0.15 -0.2944 -0.9637 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J17 compound treatment 1840.0 -578.0 -0.25 2600.0 -367.0 -0.17 -0.2952 -0.9823 370 Bio2_000418 O=C1N(C2CCC(=O)NC2=O)C(=O)c3ccccc13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J18 mock treatment 2400.0 -18.0 -0.01 2280.0 -687.0 -0.32 -0.229 -0.7242 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J19 compound treatment 1920.0 -498.0 -0.21 1720.0 -1250.0 -0.57 -0.557 -0.9098 358 Bio2_000419 N[C@@H](CCCNC(=S)N)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J20 mock treatment 2560.0 142.0 0.06 2240.0 -727.0 -0.33 -0.1933 -0.5686 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J21 compound treatment 280.0 -2140.0 -0.92 3600.0 633.0 0.29 -0.4445 -0.4609 572 Bio2_000420 CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c3c[nH]c4ccccc34)c5ccccc15 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J22 mock treatment 2160.0 -258.0 -0.11 2480.0 -487.0 -0.22 -0.2369 -0.9475 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J23 mock treatment 2760.0 342.0 0.15 3240.0 273.0 0.13 0.1927 0.9968 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 J24 mock treatment 40.0 -2380.0 -1.02 160.0 -2810.0 -1.29 -1.6359 -0.9934 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K01 mock treatment 2360.0 -58.0 -0.02 2160.0 -807.0 -0.37 -0.2801 -0.753 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K02 mock treatment 2200.0 -218.0 -0.09 2600.0 -367.0 -0.17 -0.1857 -0.9614 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K03 compound treatment 880.0 -1540.0 -0.66 600.0 -2370.0 -1.09 -1.2374 -0.9715 3419827 Bio2_000421 CN(C(Cc1ccc(OS(=O)(=O)c2cccc3cnccc23)cc1)C(=O)N4CCN(CC4)c5ccccc5)S(=O)(=O)c6cccc7cnccc67 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K04 mock treatment 2400.0 -18.0 -0.01 3120.0 153.0 0.07 0.0442 0.6252 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K05 compound treatment 1120.0 -1300.0 -0.56 2800.0 -167.0 -0.08 -0.4491 -0.797 1907778 Bio2_000422 *[C@@]1(O)C[C@@H]2O[C@@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K06 mock treatment 1880.0 -538.0 -0.23 4760.0 1790.0 0.82 0.4192 0.4897 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K07 compound treatment 3200.0 782.0 0.34 6480.0 3510.0 1.62 1.3799 0.8364 3104897 Bio2_000423 CCC(C)[C@@H](CO[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCS(=O)(=O)C)C(=O)OC(C)C)NC[C@@H](N)CS 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K08 mock treatment 1960.0 -458.0 -0.2 3760.0 793.0 0.36 0.1184 0.2859 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K09 compound treatment 40.0 -2380.0 -1.02 80.0 -2890.0 -1.33 -1.6619 -0.9917 1908 Bio2_000424 [O-][n+]1onc(c1C#N)c2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K10 mock treatment 2160.0 -258.0 -0.11 3280.0 313.0 0.14 0.0232 0.1277 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K11 compound treatment 1440.0 -978.0 -0.42 2200.0 -767.0 -0.35 -0.5469 -0.9962 3001166 Bio2_000425 C[C@H]/1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]3CSC(=O)N3)OC(=O)\C=C(\C)/CC/C=C1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K12 mock treatment 2000.0 -418.0 -0.18 2840.0 -127.0 -0.06 -0.1685 -0.8913 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K13 compound treatment 1240.0 -1180.0 -0.51 2840.0 -127.0 -0.06 -0.3996 -0.7836 284 Bio2_000426 OC(=O)c1cc(ccc1O)N(Cc2ccccc2O)Cc3cc(O)ccc3O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K14 mock treatment 1680.0 -738.0 -0.32 2720.0 -247.0 -0.11 -0.3049 -0.9042 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K15 compound treatment 520.0 -1900.0 -0.82 1080.0 -1890.0 -0.87 -1.1908 -0.9995 1907779 Bio2_000427 CC(C)n1cnc2c(NCc3ccccc3)nc(NCCO)nc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K16 mock treatment 1960.0 -458.0 -0.2 2800.0 -167.0 -0.08 -0.1937 -0.9159 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K17 compound treatment 2000.0 -418.0 -0.18 2360.0 -607.0 -0.28 -0.3246 -0.9773 3104898 Bio2_000428 CC(C)C[C@H](NC(=O)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K18 mock treatment 1880.0 -538.0 -0.23 2840.0 -127.0 -0.06 -0.205 -0.8589 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K19 compound treatment 80.0 -2340.0 -1.01 40.0 -2930.0 -1.35 -1.6628 -0.9897 1954 Bio2_000429 Cc1ccc(cc1)S(=O)(=O)/C=C/C#N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K20 mock treatment 2160.0 -258.0 -0.11 2640.0 -327.0 -0.15 -0.1849 -0.9888 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K21 compound treatment 600.0 -1820.0 -0.78 1160.0 -1810.0 -0.83 -1.1405 -0.9995 1002387 Bio2_000430 Oc1ccc(C=C(C#N)C#N)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K22 mock treatment 2360.0 -58.0 -0.02 2760.0 -207.0 -0.1 -0.0851 -0.8631 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K23 mock treatment 2840.0 422.0 0.18 3160.0 193.0 0.09 0.191 0.9456 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 K24 mock treatment 120.0 -2300.0 -0.99 80.0 -2890.0 -1.33 -1.6376 -0.9894 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L01 mock treatment 3680.0 1260.0 0.54 4720.0 1750.0 0.81 0.9536 0.9815 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L02 mock treatment 4680.0 2260.0 0.97 3640.0 673.0 0.31 0.9066 0.8881 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L03 compound treatment 1800.0 -618.0 -0.27 3880.0 913.0 0.42 0.1088 0.219 566 Bio2_000431 COc1cc(/C=C(\C#N)/C(=O)N)cc(CSc2nc3ccccc3s2)c1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L04 mock treatment 3000.0 582.0 0.25 3160.0 193.0 0.09 0.2396 0.9025 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L05 compound treatment 2360.0 -58.0 -0.02 4200.0 1230.0 0.57 0.3831 0.6753 1907780 Bio2_000432 COC1=CC(=O)OC(C1)/C=C/c2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L06 mock treatment 2600.0 182.0 0.08 3320.0 353.0 0.16 0.17 0.9442 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L07 compound treatment 2960.0 542.0 0.23 3360.0 393.0 0.18 0.2925 0.992 431 Bio2_000433 C(CN(Cc1ccccn1)Cc2ccccn2)N(Cc3ccccn3)Cc4ccccn4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L08 mock treatment 1880.0 -538.0 -0.23 5160.0 2190.0 1.01 0.5493 0.531 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L09 compound treatment 2040.0 -378.0 -0.16 2600.0 -367.0 -0.17 -0.2344 -0.9998 199 Bio2_000434 C[C@H](/C=C(\C)/C=C/C(=O)NO)C(=O)c1ccc(cc1)N(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L10 mock treatment 2440.0 22.0 0.01 2640.0 -327.0 -0.15 -0.0997 -0.6614 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L11 compound treatment 760.0 -1660.0 -0.71 1120.0 -1850.0 -0.85 -1.1049 -0.9962 437 Bio2_000435 CN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L12 mock treatment 1880.0 -538.0 -0.23 3120.0 153.0 0.07 -0.114 -0.4714 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L13 compound treatment 1240.0 -1180.0 -0.51 1560.0 -1410.0 -0.65 -0.8158 -0.9927 3001422 Bio2_000436 *C1OC(OC2OC(CC(O)C3OC(C(O)C3O)n4ccc(=O)[nH]c4=O)C(O)C(O)C2NC(=O)/C=C\*C(C)C)C(NC(=O)C)C(O)C1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L14 mock treatment 1640.0 -778.0 -0.33 2320.0 -647.0 -0.3 -0.4471 -0.9983 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L15 compound treatment 1080.0 -1340.0 -0.58 1840.0 -1130.0 -0.52 -0.7734 -0.9986 203 Bio2_000437 NC(=C(C#N)C#N)/C(=C/c1ccc2[nH]ccc2c1)/C#N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L16 mock treatment 1960.0 -458.0 -0.2 2280.0 -687.0 -0.32 -0.3628 -0.9741 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L17 compound treatment 240.0 -2180.0 -0.94 720.0 -2250.0 -1.03 -1.393 -0.9988 553 Bio2_000438 Oc1cc(C=C(C#N)C#N)ccc1[N+](=O)[O-] 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L18 mock treatment 2400.0 -18.0 -0.01 2200.0 -767.0 -0.35 -0.255 -0.7225 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L19 compound treatment 200.0 -2220.0 -0.95 520.0 -2450.0 -1.13 -1.4702 -0.9966 568 Bio2_000439 COc1ccc(C=C(C#N)C#N)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L20 mock treatment 2400.0 -18.0 -0.01 2360.0 -607.0 -0.28 -0.2029 -0.7265 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L21 compound treatment 80.0 -2340.0 -1.01 80.0 -2890.0 -1.33 -1.6498 -0.9906 5 Bio2_000440 CC(C)(C)c1cc(C=C(C#N)C#N)cc(c1O)C(C)(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L22 mock treatment 2320.0 -98.0 -0.04 2880.0 -87.3 -0.04 -0.0582 -0.9997 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L23 mock treatment 2560.0 142.0 0.06 3400.0 433.0 0.2 0.1839 0.8834 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 L24 mock treatment 80.0 -2340.0 -1.01 120.0 -2850.0 -1.31 -1.6368 -0.9915 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M01 mock treatment 3680.0 1260.0 0.54 3920.0 953.0 0.44 0.6935 0.9944 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M02 mock treatment 2880.0 462.0 0.2 3240.0 273.0 0.13 0.2291 0.9754 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M03 compound treatment 2480.0 62.0 0.03 3880.0 913.0 0.42 0.3156 0.7505 423 Bio2_000441 COC(=O)[C@@H](N)CCCNC(=N)N[N+](=O)[O-] 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M04 mock treatment 2320.0 -98.0 -0.04 3960.0 993.0 0.46 0.2929 0.6391 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M05 compound treatment 560.0 -1860.0 -0.8 1240.0 -1730.0 -0.79 -1.1267 -1.0 321 Bio2_000442 O=c1cc(oc2c(cccc12)c3ccccc3)N4CCOCC4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M06 mock treatment 2960.0 542.0 0.23 4200.0 1230.0 0.57 0.5656 0.9229 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M07 compound treatment 80.0 -2340.0 -1.01 80.0 -2890.0 -1.33 -1.6498 -0.9906 243 Bio2_000443 O=C1C=C(Nc2ccccc2)C(=O)c3cccnc13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M08 mock treatment 2320.0 -98.0 -0.04 3880.0 913.0 0.42 0.2669 0.6329 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M09 compound treatment 40.0 -2380.0 -1.02 80.0 -2890.0 -1.33 -1.6619 -0.9917 1059329 Bio2_000444 Nc1ncnc2n(cc(I)c12)C3OC(CO)C(O)C3O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M10 mock treatment 1440.0 -978.0 -0.42 2760.0 -207.0 -0.1 -0.3648 -0.8459 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M11 compound treatment 160.0 -2260.0 -0.97 240.0 -2730.0 -1.25 -1.5734 -0.992 3104900 Bio2_000445 C/C(=C\CCC1C=CC(OC1O)C2=CC(=O)OC2O)/CCC3=C(C)CCCC3(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M12 mock treatment 1840.0 -578.0 -0.25 2480.0 -487.0 -0.22 -0.3342 -0.9987 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M13 compound treatment 600.0 -1820.0 -0.78 1000.0 -1970.0 -0.9 -1.1925 -0.9974 192 Bio2_000446 CCCCC(C)/C=C(\C)/C=C(\C)/C(=O)NC1=CC(O)(\C=C\C=C\C=C\C(=O)NC2=C(O)CCC2=O)C3OC3C1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M14 mock treatment 1920.0 -498.0 -0.21 2440.0 -527.0 -0.24 -0.3229 -0.9981 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M15 compound treatment 1680.0 -738.0 -0.32 3040.0 72.7 0.03 -0.2008 -0.6292 907409 Bio2_000447 CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M16 mock treatment 2000.0 -418.0 -0.18 2520.0 -447.0 -0.21 -0.2726 -0.9978 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M17 compound treatment 2680.0 262.0 0.11 2600.0 -367.0 -0.17 -0.0398 -0.1959 419 Bio2_000448 CC1=NN(C(=O)C1)c2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M18 mock treatment 2200.0 -218.0 -0.09 2680.0 -287.0 -0.13 -0.1597 -0.9859 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M19 compound treatment 40.0 -2380.0 -1.02 80.0 -2890.0 -1.33 -1.6619 -0.9917 3002144 Bio2_000449 CN1C(=O)[C@@]23CC4=CC=C[C@H](O)[C@H]4N3C(=O)[C@@]1(CO)[S+](C)S2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M20 mock treatment 2680.0 262.0 0.11 3640.0 673.0 0.31 0.2984 0.9064 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M21 compound treatment 2160.0 -258.0 -0.11 2720.0 -247.0 -0.11 -0.1589 -0.9999 638 Bio2_000450 C/C(=C(\C#N)/C(=O)Nc1cc(Br)ccc1Br)/O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M22 mock treatment 1920.0 -498.0 -0.21 3400.0 433.0 0.2 -0.0108 -0.0369 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M23 mock treatment 2640.0 222.0 0.1 3000.0 32.7 0.02 0.0781 0.8085 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 M24 mock treatment 120.0 -2300.0 -0.99 120.0 -2850.0 -1.31 -1.6246 -0.9904 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N01 mock treatment 4640.0 2220.0 0.96 3840.0 873.0 0.4 0.9595 0.9257 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N02 mock treatment 3000.0 582.0 0.25 4240.0 1270.0 0.59 0.5908 0.9282 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N03 compound treatment 3040.0 622.0 0.27 4120.0 1150.0 0.53 0.5639 0.9499 3104901 Bio2_000451 CCCc1cc(OC)ccc1C.CC12CCCCC2CCC1NCCCCCCN3C(=O)C=CC3=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N04 mock treatment 160.0 -2260.0 -0.97 3320.0 353.0 0.16 -0.572 -0.581 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N05 compound treatment 240.0 -2180.0 -0.94 560.0 -2410.0 -1.11 -1.4451 -0.9965 325 Bio2_000452 N/C(=C(/C#N)\C(=C(/N)\Sc1ccccc1N)\C#N)/Sc2ccccc2N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N06 mock treatment 1960.0 -458.0 -0.2 2640.0 -327.0 -0.15 -0.2457 -0.9912 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N07 compound treatment 40.0 -2380.0 -1.02 40.0 -2930.0 -1.35 -1.675 -0.9908 2430 Bio2_000453 CC(C)C1NC(=O)C(C)OC(=O)C(NC(=O)C(OC(=O)C(NC(=O)C(C)OC(=O)C(NC(=O)C(OC(=O)C(NC(=O)C(C)OC(=O)C(NC(=O)C(OC1=O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N08 mock treatment 2280.0 -138.0 -0.06 3480.0 513.0 0.24 0.1247 0.513 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N09 compound treatment 3520.0 1100.0 0.47 5440.0 2470.0 1.14 1.1391 0.9247 3002149 Bio2_000454 *[C@@H]1[C@H]([C@@H]2CN(C[C@](O)(CC)C2)CCc3c1[nH]c4ccccc34)c5cc6c(cc5OC)N(C)[C@@H]7[C@@]86CCN9CC=C[C@](CC)([C@H]98)[C@@H](O)[C@]7(O)C(=O)OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N10 mock treatment 3080.0 662.0 0.28 2880.0 -87.3 -0.04 0.1729 0.6014 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N11 compound treatment 160.0 -2260.0 -0.97 120.0 -2850.0 -1.31 -1.6125 -0.9892 3002210 Bio2_000455 *CCCCCCNOc1cccc2c(Cl)cccc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N12 mock treatment 1720.0 -698.0 -0.3 2000.0 -967.0 -0.44 -0.5268 -0.9817 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N13 compound treatment 1960.0 -458.0 -0.2 2320.0 -647.0 -0.3 -0.3498 -0.9799 293 Bio2_000456 COC[C@H]1OC(=O)c2coc3C(=O)C4=C([C@@H](C[C@@]5(C)C4CCC5=O)OC(=O)C)[C@]1(C)c23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N14 mock treatment 2160.0 -258.0 -0.11 3600.0 633.0 0.29 0.1272 0.4086 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N15 compound treatment 1360.0 -1060.0 -0.46 2160.0 -807.0 -0.37 -0.5842 -0.9949 677 Bio2_000457 C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc2ccncc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N16 mock treatment 3240.0 822.0 0.35 2920.0 -47.3 -0.02 0.2346 0.6623 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N17 compound treatment 2600.0 182.0 0.08 2840.0 -127.0 -0.06 0.0139 0.1426 3000363 Bio2_000458 COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N18 mock treatment 2680.0 262.0 0.11 3080.0 113.0 0.05 0.1163 0.9379 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N19 compound treatment 1520.0 -898.0 -0.39 1440.0 -1530.0 -0.7 -0.7697 -0.9603 207 Bio2_000459 CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)/C=C/S(=O)(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N20 mock treatment 2840.0 422.0 0.18 3440.0 473.0 0.22 0.282 0.996 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N21 compound treatment 2480.0 62.0 0.03 2600.0 -367.0 -0.17 -0.1006 -0.5883 352 Bio2_000460 CN(C)c1cccc(c1)C(=O)Nc2ccc(C)c(NC(=O)c3ccc(O)cc3)c2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N22 mock treatment 3080.0 662.0 0.28 2960.0 -7.32 0.0 0.1989 0.6987 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N23 mock treatment 2480.0 62.0 0.03 3240.0 273.0 0.13 0.1075 0.8387 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 N24 mock treatment 120.0 -2300.0 -0.99 120.0 -2850.0 -1.31 -1.6246 -0.9904 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O01 mock treatment 3360.0 942.0 0.41 3040.0 72.7 0.03 0.3101 0.7628 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O02 mock treatment 4040.0 1620.0 0.7 2680.0 -287.0 -0.13 0.3998 0.5632 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O03 compound treatment 4040.0 1620.0 0.7 3040.0 72.7 0.03 0.5169 0.7401 3002219 Bio2_000461 *CCC(NC(=O)c1ccc(cc1)N(C)Cc2cnc3nc(N)nc(N)c3n2)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O04 mock treatment 3720.0 1300.0 0.56 3920.0 953.0 0.44 0.7057 0.9926 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O05 compound treatment 2480.0 62.0 0.03 3800.0 833.0 0.38 0.2896 0.7545 1001921 Bio2_000462 Clc1ccc(cn1)C2CC3CCC2N3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O06 mock treatment 3120.0 702.0 0.3 3720.0 753.0 0.35 0.4582 0.9977 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O07 compound treatment 2480.0 62.0 0.03 5080.0 2110.0 0.97 0.7058 0.7262 381 Bio2_000463 CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3CCCC(=O)O3)[C@@H]12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O08 mock treatment 2600.0 182.0 0.08 4400.0 1430.0 0.66 0.5212 0.7856 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O09 compound treatment 1200.0 -1220.0 -0.52 3120.0 153.0 0.07 -0.3208 -0.6069 1000019 Bio2_000464 CO[C@@]12[C@H]3N[C@H]3CN2C4=C([C@H]1COC(=O)N)C(=O)C(=C(C)C4=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O10 mock treatment 3120.0 702.0 0.3 4640.0 1670.0 0.77 0.7573 0.9166 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O11 compound treatment 1880.0 -538.0 -0.23 3560.0 593.0 0.27 0.0291 0.0813 281 Bio2_000465 Ic1cccc2c(cccc12)S(=O)(=O)N3CCCNCC3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O12 mock treatment 2640.0 222.0 0.1 3560.0 593.0 0.27 0.2602 0.9011 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O13 compound treatment 1520.0 -898.0 -0.39 2120.0 -847.0 -0.39 -0.5486 -1.0 3002225 Bio2_000466 Clc1cccc2c(cccc12)S(=O)(=O)N3CC*CCC3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O14 mock treatment 2640.0 222.0 0.1 3080.0 113.0 0.05 0.1041 0.9588 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O15 compound treatment 1680.0 -738.0 -0.32 2240.0 -727.0 -0.33 -0.4609 -0.9997 438 Bio2_000467 CCOC(=O)C1=C(C)NC(=S)NC1c2cccc(O)c2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O16 mock treatment 1840.0 -578.0 -0.25 2680.0 -287.0 -0.13 -0.2692 -0.9562 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O17 compound treatment 2200.0 -218.0 -0.09 2800.0 -167.0 -0.08 -0.1207 -0.9952 656 Bio2_000468 Oc1c(Br)cc(/C=C/2\C(=O)Nc3ccc(I)cc23)cc1Br 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O18 mock treatment 2720.0 302.0 0.13 3000.0 32.7 0.02 0.1025 0.7837 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O19 compound treatment 1440.0 -978.0 -0.42 1280.0 -1690.0 -0.78 -0.846 -0.9586 3104902 Bio2_000469 CC[C@]1(CC[C@@H](O1)[C@]2(C)CC[C@]3(C[C@H](O)[C@@H](C)[C@H](O3)[C@@H](C)C/C=C(\C)/OO)O2)[C@@H]4O[C@H](C[C@@H]4C)[C@H]5O[C@@](O)(CO)[C@H](C)C[C@@H]5C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O20 mock treatment 2760.0 342.0 0.15 3200.0 233.0 0.11 0.1796 0.9878 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O21 compound treatment 2720.0 302.0 0.13 2800.0 -167.0 -0.08 0.0374 0.2479 1907781 Bio2_000470 CO[C@@H]1C[C@@H](CC[C@H]1O)/C=C(\C)/[C@H]2OC(=O)C3CCCCN3C(=O)C(=O)[C@]4(O)O[C@@H]([C@H](C[C@H]4C)OC)[C@H](C[C@@H](C)C\C(=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)\C)OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O22 mock treatment 2800.0 382.0 0.16 2480.0 -487.0 -0.22 -0.0423 -0.1522 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O23 mock treatment 2480.0 62.0 0.03 2920.0 -47.3 -0.02 0.0035 0.1005 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 O24 mock treatment 120.0 -2300.0 -0.99 80.0 -2890.0 -1.33 -1.6376 -0.9894 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P01 mock treatment 4880.0 2460.0 1.06 4720.0 1750.0 0.81 1.3186 0.9909 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P02 mock treatment 4480.0 2060.0 0.89 4320.0 1350.0 0.62 1.0669 0.9849 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P03 compound treatment 4320.0 1900.0 0.82 4640.0 1670.0 0.77 1.1222 0.9995 201 Bio2_000471 COC(=O)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)CF 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P04 mock treatment 5480.0 3060.0 1.32 4400.0 1430.0 0.66 1.397 0.9487 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P05 compound treatment 4040.0 1620.0 0.7 4280.0 1310.0 0.6 0.92 0.9974 2217 Bio2_000472 CS(=O)(=O)Nc1ccc(cc1OC2CCCCC2)[N+](=O)[O-] 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P06 mock treatment 3600.0 1180.0 0.51 3720.0 753.0 0.35 0.6042 0.9824 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P07 compound treatment 520.0 -1900.0 -0.82 1400.0 -1570.0 -0.72 -1.0868 -0.9981 1917 Bio2_000473 CC1=C(C)C(=O)C(=C(C)C1=O)CCCCC#CCCCC#CCO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P08 mock treatment 2000.0 -418.0 -0.18 1800.0 -1170.0 -0.54 -0.5067 -0.8951 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P09 compound treatment 2520.0 102.0 0.04 3200.0 233.0 0.11 0.1067 0.9225 3002232 Bio2_000474 *CC/C(=C/Cc1c(O)c2C(=O)OCc2c(C)c1OC)/C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P10 mock treatment 3280.0 862.0 0.37 3000.0 32.7 0.02 0.2728 0.7352 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P11 compound treatment 1760.0 -658.0 -0.28 1880.0 -1090.0 -0.5 -0.5536 -0.9637 2288 Bio2_000475 CC(=CCC(O)C1=CC(=O)c2c(O)ccc(O)c2C1=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P12 mock treatment 2600.0 182.0 0.08 2320.0 -647.0 -0.3 -0.1551 -0.5041 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P13 compound treatment 2440.0 22.0 0.01 3000.0 32.7 0.02 0.0173 0.975 3104904 Bio2_000476 C1C[C@H]2CCCCCC[C@H]3CCN4CCC[C@H](CCCCCC[C@H]5CCN(C1)[C@@H]2O5)[C@H]4O3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P14 mock treatment 3480.0 1060.0 0.46 2920.0 -47.3 -0.02 0.3076 0.6727 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P15 compound treatment 1680.0 -738.0 -0.32 1840.0 -1130.0 -0.52 -0.591 -0.9723 1907782 Bio2_000477 Oc1ccc(/C=C(/C#N)\C(=O)OC\C=C\c2ccccc2)cc1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P16 mock treatment 2720.0 302.0 0.13 3000.0 32.7 0.02 0.1025 0.7837 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P17 compound treatment 120.0 -2300.0 -0.99 160.0 -2810.0 -1.29 -1.6116 -0.9913 3104917 Bio2_000478 C/C=C/C\C=C\CCC(=O)[C@H]1O[C@H]1C(=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P18 mock treatment 1880.0 -538.0 -0.23 2800.0 -167.0 -0.08 -0.218 -0.8941 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P19 compound treatment 1720.0 -698.0 -0.3 1240.0 -1730.0 -0.79 -0.7739 -0.9114 1395 Bio2_000479 CC(COc1ccccc1)N(CCCl)Cc2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P20 mock treatment 3400.0 982.0 0.42 3280.0 313.0 0.14 0.4003 0.8973 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P21 compound treatment 3160.0 742.0 0.32 3320.0 353.0 0.16 0.3403 0.9507 1303231 Bio2_000480 CN(C)CC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P22 mock treatment 2800.0 382.0 0.16 3880.0 913.0 0.42 0.4129 0.9162 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P23 mock treatment 2520.0 102.0 0.04 3560.0 593.0 0.27 0.2237 0.8105 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1362 P24 mock treatment 120.0 -2300.0 -0.99 120.0 -2850.0 -1.31 -1.6246 -0.9904 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A01 mock treatment 9520.0 2790.0 1.2 4800.0 2080.0 0.95 1.5245 0.9935 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A02 mock treatment 7320.0 593.0 0.26 4320.0 1600.0 0.73 0.6994 0.9001 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A03 compound treatment 6240.0 -487.0 -0.21 4280.0 1560.0 0.72 0.358 0.4802 315 KBio2_000001 CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A04 compound treatment 6360.0 -367.0 -0.16 4640.0 1920.0 0.88 0.5115 0.5715 85 KBio2_000002 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)NC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A05 compound treatment 6040.0 -687.0 -0.3 3480.0 756.0 0.35 0.0371 0.0812 29 KBio2_000003 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NCCCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A06 compound treatment 6800.0 73.3 0.03 3360.0 636.0 0.29 0.2292 0.7788 302 KBio2_000004 CCCCC[C@H](O)C/C=C/1\[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A07 compound treatment 4280.0 -2450.0 -1.05 3640.0 916.0 0.42 -0.4461 -0.3936 10 KBio2_000005 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N[C@H](C)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A08 compound treatment 6400.0 -327.0 -0.14 3520.0 796.0 0.37 0.1595 0.4069 262 KBio2_000006 CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A09 compound treatment 5240.0 -1490.0 -0.64 2960.0 236.0 0.11 -0.3753 -0.5787 100 KBio2_000007 C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)C[C@H](O)C3=C)/CCC[C@]12C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A10 compound treatment 4720.0 -2010.0 -0.86 2600.0 -124.0 -0.06 -0.6505 -0.7521 1000034 KBio2_000008 CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A11 compound treatment 5840.0 -887.0 -0.38 3280.0 556.0 0.26 -0.0888 -0.1934 148 KBio2_000009 CCCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A12 compound treatment 4680.0 -2050.0 -0.88 2320.0 -404.0 -0.19 -0.7537 -0.8378 122 KBio2_000010 C(c1c[nH]c2ccccc12)c3c[nH]c4ccccc34 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A13 compound treatment 5120.0 -1610.0 -0.69 3160.0 436.0 0.2 -0.3468 -0.4819 150 KBio2_000011 CCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A14 compound treatment 5160.0 -1570.0 -0.67 3000.0 276.0 0.13 -0.3866 -0.5639 31 KBio2_000012 CCCCCCCCCCCCCCC[C@H](O)[C@@H](N)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A15 compound treatment 5280.0 -1450.0 -0.62 2920.0 196.0 0.09 -0.3761 -0.5983 171 KBio2_000013 CCCCCCCC/C=C\CCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCC/C=C\CCCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A16 compound treatment 5880.0 -847.0 -0.36 3080.0 356.0 0.16 -0.1416 -0.3548 33 KBio2_000014 CCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@H](O)c2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A17 compound treatment 5720.0 -1010.0 -0.43 3760.0 1040.0 0.48 0.0308 0.0478 141 KBio2_000015 CCCCC/C=C\CC1OC1C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A18 compound treatment 5520.0 -1210.0 -0.52 3440.0 716.0 0.33 -0.1341 -0.2181 34 KBio2_000016 CCCCCCCCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@H](O)c2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A19 compound treatment 5960.0 -767.0 -0.33 3720.0 996.0 0.46 0.0908 0.1608 1000003 KBio2_000017 CCCCC/C=C\C[C@@H](O)/C=C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A20 compound treatment 5920.0 -807.0 -0.35 3960.0 1240.0 0.57 0.1566 0.2352 223 KBio2_000018 CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A21 compound treatment 5600.0 -1130.0 -0.48 3240.0 516.0 0.24 -0.1748 -0.3239 46 KBio2_000019 CCCCC/C=C\C[C@H](O)/C=C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A22 compound treatment 7120.0 393.0 0.17 2720.0 -3.75 0.0 0.1184 0.6999 268 KBio2_000020 CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A23 mock treatment 5520.0 -1210.0 -0.52 3760.0 1040.0 0.48 -0.03 -0.0426 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 A24 mock treatment 280.0 -6450.0 -2.77 120.0 -2600.0 -1.2 -2.807 -0.9295 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B01 mock treatment 7200.0 473.0 0.2 4160.0 1440.0 0.66 0.6109 0.884 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B02 mock treatment 6600.0 -127.0 -0.05 4040.0 1320.0 0.61 0.3894 0.6409 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B03 compound treatment 2960.0 -3770.0 -1.62 1480.0 -1240.0 -0.57 -1.5499 -0.9022 1000048 KBio2_000021 CC(C)COCC(CN(Cc1ccccc1)c2ccccc2)N3CCCC3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B04 compound treatment 480.0 -6250.0 -2.69 360.0 -2360.0 -1.09 -2.6682 -0.9207 2139 KBio2_000022 O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4[C@@H]([C@H]32)[C@@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B05 compound treatment 7960.0 1230.0 0.53 5480.0 2760.0 1.27 1.2712 0.9253 32 KBio2_000023 C/C(=C/1\C(=O)C2C3C(Cc4cccc5[nH]cc3c45)C(C)(C)N2C1=O)/O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B06 compound treatment 200.0 -6530.0 -2.81 80.0 -2640.0 -1.22 -2.8444 -0.9299 3000451 KBio2_000024 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5cccc(O)c5cc4Cn3c2=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B07 compound treatment 7120.0 393.0 0.17 3680.0 956.0 0.44 0.4305 0.9138 3000787 KBio2_000025 [O-][N+](=O)c1ccc(cc1)c2ccc(/C=N/N3CC(=O)NC3=O)o2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B08 compound treatment 80.0 -6650.0 -2.86 120.0 -2600.0 -1.2 -2.8679 -0.9254 2127 KBio2_000026 CC1(C)CCC2=C(O1)c3ccccc3C(=O)C2=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B09 compound treatment 4440.0 -2290.0 -0.98 3120.0 396.0 0.18 -0.5666 -0.5665 35 KBio2_000027 CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B10 compound treatment 80.0 -6650.0 -2.86 40.0 -2680.0 -1.23 -2.8939 -0.9295 3103826 KBio2_000028 C/C/1=C\CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3CC1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B11 compound treatment 2520.0 -4210.0 -1.81 560.0 -2160.0 -0.99 -1.9828 -0.9603 3103827 KBio2_000029 N/C(=N\C(=O)c1nc(Cl)c(N)nc1N)/NCc2ccc(Cl)cc2Cl 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B12 compound treatment 720.0 -6010.0 -2.58 520.0 -2200.0 -1.01 -2.5432 -0.9165 1907748 KBio2_000030 CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B13 compound treatment 3720.0 -3010.0 -1.29 3080.0 356.0 0.16 -0.7985 -0.6126 3000452 KBio2_000031 *CCN1C(=O)[C@H](OC(=O)C)[C@@H](Sc2ccccc12)c3ccc(OC)cc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B14 compound treatment 40.0 -6690.0 -2.88 80.0 -2640.0 -1.22 -2.893 -0.9266 3000453 KBio2_000032 C[C@@H]1CC2OC(=O)C(=C)C2[C@H](O)[C@@]3(C)[C@H]1C=CC3=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B15 compound treatment 6200.0 -527.0 -0.23 3760.0 1040.0 0.48 0.1768 0.335 357 KBio2_000033 Cc1cccc(CCN2CCC(CC2)C(=O)c3ccc(NS(=O)(=O)C)cc3)n1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B16 compound treatment 4760.0 -1970.0 -0.85 2720.0 -3.75 0.0 -0.5993 -0.7085 1000105 KBio2_000034 CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B17 compound treatment 1280.0 -5450.0 -2.34 840.0 -1880.0 -0.87 -2.2688 -0.9085 39 KBio2_000035 Nc1c(S(=O)C(F)(F)F)c(C#N)nn1c2c(Cl)cc(cc2Cl)C(F)(F)F 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B18 compound treatment 4600.0 -2130.0 -0.91 2760.0 36.3 0.02 -0.6349 -0.6941 1907749 KBio2_000036 CCOC(=O)CN1C(=O)CC(C[C@@H](O)C2C[C@@H](C)C[C@H](C)C2=O)CC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B19 compound treatment 5280.0 -1450.0 -0.62 3040.0 316.0 0.15 -0.3371 -0.5276 359 KBio2_000037 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)C(=O)NCC2CCCCN2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B20 compound treatment 1360.0 -5370.0 -2.31 1040.0 -1680.0 -0.77 -2.1795 -0.8953 1907750 KBio2_000038 CC[C@@H]1/C=C(\C)/C[C@H](C)C[C@H](OC)[C@H]2O[C@](O)([C@H](C)C[C@@H]2OC)C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@H](C)[C@@H](O)CC1=O)\C(=C\[C@@H]4CC[C@@H](O)[C@@H](C4)OC)\C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B21 compound treatment 5240.0 -1490.0 -0.64 3080.0 356.0 0.16 -0.3363 -0.5095 41 KBio2_000039 OC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B22 compound treatment 4520.0 -2210.0 -0.95 2480.0 -244.0 -0.11 -0.7503 -0.7852 2349 KBio2_000040 CC12CC=C3C(CCC4=CC(=O)C=CC43C)C2CC[C@@H]1C(=O)CN5CCN(CC5)c6cc(nc(n6)N7CCCC7)N8CCCC8 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B23 mock treatment 5600.0 -1130.0 -0.48 3480.0 756.0 0.35 -0.0967 -0.1622 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 B24 mock treatment 240.0 -6490.0 -2.79 280.0 -2440.0 -1.12 -2.7672 -0.9201 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C01 mock treatment 8600.0 1870.0 0.81 3160.0 436.0 0.2 0.7115 0.857 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C02 mock treatment 7800.0 1070.0 0.46 4640.0 1920.0 0.88 0.9495 0.9545 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C03 compound treatment 2440.0 -4290.0 -1.84 4360.0 1640.0 0.75 -0.7716 -0.3875 87 KBio2_000041 CCCCC/C=C\C[C@H](OO)/C=C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C04 compound treatment 5840.0 -887.0 -0.38 3480.0 756.0 0.35 -0.0238 -0.046 264 KBio2_000042 CC/C=C\C/C=C\C/C=C\CCCCCCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C05 compound treatment 4280.0 -2450.0 -1.05 4000.0 1280.0 0.59 -0.3291 -0.2731 301 KBio2_000043 COCCCCCCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C06 compound treatment 6720.0 -6.67 0.0 3840.0 1120.0 0.51 0.3609 0.7031 233 KBio2_000044 CCCCCCCCCCC/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C07 compound treatment 5520.0 -1210.0 -0.52 3080.0 356.0 0.16 -0.2511 -0.4615 61 KBio2_000045 CCCCC[C@H](O)/C=C/C=C\CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C08 compound treatment 5720.0 -1010.0 -0.43 3800.0 1080.0 0.49 0.0438 0.0666 256 KBio2_000046 CCCCC/C=C\C/C=C\CCCCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C09 compound treatment 5560.0 -1170.0 -0.5 2920.0 196.0 0.09 -0.291 -0.5708 90 KBio2_000047 CCCCC[C@H](OO)/C=C/C=C\CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C10 compound treatment 3360.0 -3370.0 -1.45 3440.0 716.0 0.33 -0.7909 -0.5327 221 KBio2_000048 CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C11 compound treatment 8720.0 1990.0 0.86 3640.0 916.0 0.42 0.9041 0.9465 304 KBio2_000049 CCCCC[C@H](O)CC[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C12 compound treatment 5200.0 -1530.0 -0.66 2400.0 -324.0 -0.15 -0.5695 -0.846 260 KBio2_000050 CC/C=C\C/C=C\C/C=C\CCCCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C13 compound treatment 3120.0 -3610.0 -1.55 2360.0 -364.0 -0.17 -1.2151 -0.7788 1000009 KBio2_000051 C/C(=C\C=C\C(=C/C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C14 compound treatment 6280.0 -447.0 -0.19 3560.0 836.0 0.38 0.1361 0.3165 1000007 KBio2_000052 CCCCCCCCCCCCCCCCOC[C@@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C15 compound treatment 6240.0 -487.0 -0.21 2520.0 -204.0 -0.09 -0.2142 -0.9343 149 KBio2_000053 CCCCC(=O)/C=C/C=C\CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C16 compound treatment 4440.0 -2290.0 -0.98 3000.0 276.0 0.13 -0.6056 -0.6107 55 KBio2_000054 CC(=CCC/C(=C/CC/C(=C/CSCC(=O)O)/C)/C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C17 compound treatment 6960.0 233.0 0.1 3160.0 436.0 0.2 0.2128 0.9487 143 KBio2_000055 CCCCCC1OC1C/C=C\C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C18 compound treatment 4440.0 -2290.0 -0.98 2440.0 -284.0 -0.13 -0.7876 -0.794 217 KBio2_000056 O[C@@H](COc1cccc(c1)C(F)(F)F)/C=C/[C@H]2[C@H](O)C[C@H](O)[C@@H]2C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C19 compound treatment 4360.0 -2370.0 -1.02 2560.0 -164.0 -0.08 -0.773 -0.7573 50 KBio2_000057 CCCCC[C@H](O)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C20 compound treatment 5920.0 -807.0 -0.35 2960.0 236.0 0.11 -0.1685 -0.4635 231 KBio2_000058 CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C21 compound treatment 6440.0 -287.0 -0.12 3400.0 676.0 0.31 0.1327 0.3967 89 KBio2_000059 CCCCC[C@H](OO)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C22 compound treatment 5680.0 -1050.0 -0.45 3400.0 676.0 0.31 -0.0984 -0.1799 92 KBio2_000060 CCCCC/C=C\CC1OC1CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C23 mock treatment 6760.0 33.3 0.01 3040.0 316.0 0.15 0.113 0.7731 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 C24 mock treatment 280.0 -6450.0 -2.77 120.0 -2600.0 -1.2 -2.807 -0.9295 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D01 mock treatment 7720.0 993.0 0.43 2720.0 -3.75 0.0 0.3009 0.7042 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D02 mock treatment 3400.0 -3330.0 -1.43 3920.0 1200.0 0.55 -0.6227 -0.4063 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D03 compound treatment 600.0 -6130.0 -2.63 480.0 -2240.0 -1.03 -2.5927 -0.9162 43 KBio2_000061 Fc1ccc(cc1)C(N2CCN(C/C=C/c3ccccc3)CC2)c4ccc(F)cc4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D04 compound treatment 240.0 -6490.0 -2.79 80.0 -2640.0 -1.22 -2.8322 -0.9307 1531 KBio2_000062 O=c1n([se]c2ccccc12)c3ccccc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D05 compound treatment 2800.0 -3930.0 -1.69 1680.0 -1040.0 -0.48 -1.5335 -0.8735 3104253 KBio2_000063 CC(CCCN1CCC2(CC1)N(C)CNC2=O)c3ccc(F)cc3.Fc1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D06 compound treatment 4400.0 -2330.0 -1.0 2720.0 -3.75 0.0 -0.7088 -0.7083 1875 KBio2_000064 FC(F)(F)c1ccccc1n2ccnc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D07 compound treatment 5320.0 -1410.0 -0.6 2520.0 -204.0 -0.09 -0.494 -0.807 3000569 KBio2_000065 Cc1cc(C(=O)c2ccccc2Cc3ccccc3)c(C)[nH]1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D08 compound treatment 3000.0 -3730.0 -1.6 1840.0 -884.0 -0.41 -1.4206 -0.8592 2372 KBio2_000066 COc1cc(ccc1OC(F)F)c2ccc(=O)[nH]n2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D09 compound treatment 4080.0 -2650.0 -1.14 2400.0 -324.0 -0.15 -0.9101 -0.7928 70 KBio2_000067 CCCCC[C@H](O)CC(=O)CCc1ccc(O)c(OC)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D10 compound treatment 4440.0 -2290.0 -0.98 2240.0 -484.0 -0.22 -0.8527 -0.8457 3000570 KBio2_000068 CCCNc1ccccc1c2nc3[nH]nnc3c(=O)[nH]2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D11 compound treatment 5000.0 -1730.0 -0.74 3120.0 396.0 0.18 -0.3963 -0.5182 72 KBio2_000069 Cc1cnc(cn1)C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D12 compound treatment 3280.0 -3450.0 -1.48 1920.0 -804.0 -0.37 -1.3095 -0.8572 3000571 KBio2_000070 *C1=C[C@]2(CC)CCCN3CCc4c(C32)n1c5ccccc45 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D13 compound treatment 4760.0 -1970.0 -0.85 3760.0 1040.0 0.48 -0.2612 -0.269 74 KBio2_000071 COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D14 compound treatment 1920.0 -4810.0 -2.07 920.0 -1800.0 -0.83 -2.0482 -0.9196 2337 KBio2_000072 COc1cc2CCn3c(cc(=Nc4c(C)cc(C)cc4C)n(C)c3=O)-c2cc1OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D15 compound treatment 6040.0 -687.0 -0.3 2720.0 -3.75 0.0 -0.21 -0.7112 76 KBio2_000073 CC1(C)[C@@H](O)C[C@@H]2[C@]1(O)[C@H](O)C[C@@]3(C[C@@](C)(O)C4CC[C@H]3[C@@]2(C)O)[C@@H]4O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D16 compound treatment 5960.0 -767.0 -0.33 2760.0 36.3 0.02 -0.2214 -0.6705 1907751 KBio2_000074 CN/C(=N\c1ccc(cc1)C2=NNC(=O)CC2C)/NC#N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D17 compound treatment 4520.0 -2210.0 -0.95 3080.0 356.0 0.16 -0.5552 -0.5765 78 KBio2_000075 C[C@]1(Cc2cc(OCC(=O)O)c(Cl)c(Cl)c2C1=O)C3CCCC3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D18 compound treatment 5240.0 -1490.0 -0.64 2960.0 236.0 0.11 -0.3753 -0.5787 1000092 KBio2_000076 COc1ccc(cc1OC2CCCC2)C3CNC(=O)C3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D19 compound treatment 6640.0 -86.7 -0.04 3320.0 596.0 0.27 0.1675 0.6054 3103683 KBio2_000077 COc1ccccc1.CS[C@H](C)[C@H](OC(=O)C)C(=O)N(C)CCN(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D20 compound treatment 7280.0 553.0 0.24 2360.0 -364.0 -0.17 0.05 0.1719 2270 KBio2_000078 CCCCOc1cc(CC2CNC(=O)N2)ccc1OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D21 compound treatment 5760.0 -967.0 -0.42 3160.0 436.0 0.2 -0.1521 -0.3296 362 KBio2_000079 CCN(CC)CC(=O)Nc1c(C)cccc1C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D22 compound treatment 6400.0 -327.0 -0.14 3120.0 396.0 0.18 0.0295 0.1282 1865 KBio2_000080 Clc1cccc(Nc2nnc(c3ccccc3)c4ccccc24)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D23 mock treatment 4800.0 -1930.0 -0.83 3280.0 556.0 0.26 -0.4051 -0.4671 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 D24 mock treatment 200.0 -6530.0 -2.81 280.0 -2440.0 -1.12 -2.7793 -0.9193 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E01 mock treatment 7520.0 793.0 0.34 3840.0 1120.0 0.51 0.6042 0.9803 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E02 mock treatment 6280.0 -447.0 -0.19 3440.0 716.0 0.33 0.097 0.2545 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E03 compound treatment 7080.0 353.0 0.15 3560.0 836.0 0.38 0.3793 0.9175 308 KBio2_000081 CCCCC/C=C/C=C/1\[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E04 compound treatment 5800.0 -927.0 -0.4 3120.0 396.0 0.18 -0.153 -0.3491 94 KBio2_000082 CCCCCC1OC1C/C=C\CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E05 compound treatment 5360.0 -1370.0 -0.59 3440.0 716.0 0.33 -0.1827 -0.2712 147 KBio2_000083 CCCCCC(=O)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E06 compound treatment 4800.0 -1930.0 -0.83 3640.0 916.0 0.42 -0.288 -0.3098 1000018 KBio2_000084 CCCCC/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E07 compound treatment 7840.0 1110.0 0.48 4600.0 1880.0 0.86 0.9486 0.9614 259 KBio2_000085 CCCCC(C)(C)[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E08 compound treatment 5160.0 -1570.0 -0.67 2920.0 196.0 0.09 -0.4126 -0.607 3000590 KBio2_000086 **(*)S[C@H](/C=C/C=C/C=C\C/C=C\CCCCC)[C@@H](O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E09 compound treatment 5240.0 -1490.0 -0.64 2880.0 156.0 0.07 -0.4013 -0.6237 272 KBio2_000087 OC(=O)CCCCCCCCCCCCCCCC#C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E10 compound treatment 6720.0 -6.67 0.0 3280.0 556.0 0.26 0.1788 0.6991 3000609 KBio2_000088 *C(=O)[C@H](CS)NS[C@H](/C=C/C=C/C=C\C/C=C\CCCCC)[C@@H](O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E11 compound treatment 6200.0 -527.0 -0.23 2720.0 -3.75 0.0 -0.1614 -0.7125 300 KBio2_000089 O[C@@H](CCc1ccccc1)/C=C/[C@H]2[C@H](O)CC(=O)[C@@H]2C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E12 compound treatment 5360.0 -1370.0 -0.59 3000.0 276.0 0.13 -0.3258 -0.5418 3000610 KBio2_000090 *[C@H](/C=C/C=C/C=C\C/C=C\CCCCC)[C@@H](O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E13 compound treatment 5080.0 -1650.0 -0.71 3240.0 516.0 0.24 -0.3329 -0.4457 109 KBio2_000091 CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E14 compound treatment 5320.0 -1410.0 -0.6 2320.0 -404.0 -0.19 -0.559 -0.8834 22 KBio2_000092 CCCCC/C=C\C/C=C\CCCCCCCC(=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E15 compound treatment 4840.0 -1890.0 -0.81 2720.0 -3.75 0.0 -0.575 -0.7086 179 KBio2_000093 CCCCCCCCCCCCCCCCOC[C@H](CO)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E16 compound treatment 4040.0 -2690.0 -1.16 2760.0 36.3 0.02 -0.8052 -0.6968 270 KBio2_000094 CCCCC/C=C\C/C=C\CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E17 compound treatment 5440.0 -1290.0 -0.55 2920.0 196.0 0.09 -0.3275 -0.5841 81 KBio2_000095 CCCCCCCCCCCCCCCCOCC(COP(=O)(O)OCC[N+](C)(C)C)OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E18 compound treatment 4840.0 -1890.0 -0.81 2680.0 -43.8 -0.02 -0.588 -0.7244 229 KBio2_000096 CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E19 compound treatment 4640.0 -2090.0 -0.9 3320.0 596.0 0.27 -0.4407 -0.4697 183 KBio2_000097 CCCCCCCCCCCCCCCCOCC(CO)OC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E20 compound treatment 6680.0 -46.7 -0.02 2480.0 -244.0 -0.11 -0.0934 -0.8207 186 KBio2_000098 CCCCC[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E21 compound treatment 6560.0 -167.0 -0.07 2240.0 -484.0 -0.22 -0.208 -0.8899 181 KBio2_000099 CCCCCCCCCCCCCCCCOCC(CO)OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E22 compound treatment 5960.0 -767.0 -0.33 3520.0 796.0 0.37 0.0257 0.0522 3000631 KBio2_000100 *P(=O)OC[C@H](NC(=O)CCCCCCCCCCCCCCC)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E23 mock treatment 5720.0 -1010.0 -0.43 3040.0 316.0 0.15 -0.2033 -0.4452 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 E24 mock treatment 280.0 -6450.0 -2.77 120.0 -2600.0 -1.2 -2.807 -0.9295 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F01 mock treatment 8480.0 1750.0 0.75 2760.0 36.3 0.02 0.545 0.7226 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F02 mock treatment 6200.0 -527.0 -0.23 3120.0 396.0 0.18 -0.0313 -0.1078 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F03 compound treatment 3240.0 -3490.0 -1.5 2200.0 -524.0 -0.24 -1.2306 -0.8103 80 KBio2_000101 CN(C)C(=O)C(CCN1CCC(O)(CC1)c2ccc(Cl)cc2)(c3ccccc3)c4ccccc4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F04 compound treatment 3720.0 -3010.0 -1.29 2040.0 -684.0 -0.31 -1.1367 -0.8541 3000632 KBio2_000102 *CCNS(=O)(=O)c1cccc2c(Cl)cccc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F05 compound treatment 6040.0 -687.0 -0.3 3040.0 316.0 0.15 -0.106 -0.322 372 KBio2_000103 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2cc(OC)c(OC)c(OC)c2)cc1OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F06 compound treatment 7360.0 633.0 0.27 2840.0 116.0 0.05 0.2304 0.83 47 KBio2_000104 CC(=CCC/C(=C/CC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)/C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F07 compound treatment 5320.0 -1410.0 -0.6 2960.0 236.0 0.11 -0.351 -0.571 82 KBio2_000105 Nc1cc(nc(N)[n+]1[O-])N2CCCCC2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F08 compound treatment 120.0 -6610.0 -2.84 160.0 -2560.0 -1.18 -2.8427 -0.9241 3000633 KBio2_000106 Cc1ccc(C(=O)*2****o2)c3nc4c(C(=O)*5****o5)c(N)c(=O)c(C)c4oc13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F09 compound treatment 6080.0 -647.0 -0.28 3160.0 436.0 0.2 -0.0548 -0.1599 84 KBio2_000107 Nc1cc(nc(N)[n+]1OS(=O)(=O)O)N2CCCCC2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F10 compound treatment 1000.0 -5730.0 -2.46 760.0 -1960.0 -0.9 -2.38 -0.9073 1907752 KBio2_000108 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCc1ccc(O)c(OC)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F11 compound treatment 3560.0 -3170.0 -1.36 1920.0 -804.0 -0.37 -1.2243 -0.8676 86 KBio2_000109 COC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCCN(C)Cc3ccccc3)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F12 compound treatment 3040.0 -3690.0 -1.59 1560.0 -1160.0 -0.54 -1.4995 -0.8961 331 KBio2_000110 COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F13 compound treatment 480.0 -6250.0 -2.69 400.0 -2320.0 -1.07 -2.6552 -0.9184 110 KBio2_000111 COC(=O)C1=C(C)NC(=C(C1c2ccccc2[N+](=O)[O-])C(=O)OC)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F14 compound treatment 3880.0 -2850.0 -1.22 2520.0 -204.0 -0.09 -0.9319 -0.759 333 KBio2_000112 NC(=S)/C(=C/c1ccc(O)c(O)c1)/C#N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F15 compound treatment 4960.0 -1770.0 -0.76 2760.0 36.3 0.02 -0.5255 -0.6914 112 KBio2_000113 OC(=O)c1cccnc1Nc2cccc(c2)C(F)(F)F 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F16 compound treatment 3160.0 -3570.0 -1.53 1520.0 -1200.0 -0.55 -1.476 -0.9051 203 KBio2_000114 NC(=C(C#N)C#N)/C(=C/c1ccc2[nH]ccc2c1)/C#N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F17 compound treatment 1320.0 -5410.0 -2.33 800.0 -1920.0 -0.88 -2.2697 -0.9123 907431 KBio2_000115 COC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCCCN3CCC(CC3)(c4ccccc4)c5ccccc5)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F18 compound treatment 3600.0 -3130.0 -1.34 2200.0 -524.0 -0.24 -1.1211 -0.8207 3 KBio2_000116 Oc1ccc(/C=C(\C#N)/C(=O)NCc2ccccc2)cc1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F19 compound treatment 1960.0 -4770.0 -2.05 960.0 -1760.0 -0.81 -2.023 -0.9176 115 KBio2_000117 COCCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC(C)C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F20 compound treatment 80.0 -6650.0 -2.86 40.0 -2680.0 -1.23 -2.8939 -0.9295 208 KBio2_000118 CC(C)(C)c1cc(/C=C(\C#N)/C(=S)N)cc(c1O)C(C)(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F21 compound treatment 4280.0 -2450.0 -1.05 2440.0 -284.0 -0.13 -0.8363 -0.7887 117 KBio2_000119 CCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F22 compound treatment 4720.0 -2010.0 -0.86 3200.0 476.0 0.22 -0.4554 -0.5115 2413 KBio2_000120 CC(C)CC(NC(=O)CNC(=O)C(C)(C)NC(=O)C(NC(=O)C(C)(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C1CCCN1C(=O)C(C)(C)NC(=O)C)C(C)C)C(=O)NC(C)(C)C(=O)N2CCCC2C(=O)NC(C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CO)Cc3ccccc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F23 mock treatment 6720.0 -6.67 0.0 2640.0 -83.8 -0.04 -0.0293 -0.7577 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 F24 mock treatment 200.0 -6530.0 -2.81 120.0 -2600.0 -1.2 -2.8314 -0.9278 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G01 mock treatment 7360.0 633.0 0.27 3600.0 876.0 0.4 0.4775 0.9818 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G02 mock treatment 6920.0 193.0 0.08 3880.0 1160.0 0.53 0.4347 0.8079 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G03 compound treatment 5800.0 -927.0 -0.4 3080.0 356.0 0.16 -0.166 -0.3852 83 KBio2_000121 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G04 compound treatment 6360.0 -367.0 -0.16 3480.0 756.0 0.35 0.1344 0.3519 191 KBio2_000122 CCCc1c(O)c(ccc1OCCCCc2nnn[nH]2)C(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G05 compound treatment 5320.0 -1410.0 -0.6 3200.0 476.0 0.22 -0.2729 -0.4242 173 KBio2_000123 CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](CO)OC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G06 compound treatment 5440.0 -1290.0 -0.55 3040.0 316.0 0.15 -0.2885 -0.5042 3000641 KBio2_000124 *CCOP(=O)(O)OC[C@H](O)COCCCCCCCCCCCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G07 compound treatment 5800.0 -927.0 -0.4 2680.0 -43.8 -0.02 -0.296 -0.7419 177 KBio2_000125 CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC/C=C\C/C=C\CCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G08 compound treatment 7200.0 473.0 0.2 3240.0 516.0 0.24 0.3118 0.9971 111 KBio2_000126 CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G09 compound treatment 6160.0 -567.0 -0.24 2800.0 76.3 0.04 -0.1475 -0.5992 175 KBio2_000127 CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G10 compound treatment 5240.0 -1490.0 -0.64 2800.0 76.3 0.04 -0.4273 -0.6673 36 KBio2_000128 CCCCCCCCCCCCCC(=O)N[C@H](C)[C@@H](O)c1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G11 compound treatment 5280.0 -1450.0 -0.62 1960.0 -764.0 -0.35 -0.6883 -0.9634 102 KBio2_000129 C[C@H](CC[C@@H](O)C(C)(C)O)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)CCC3=C)/CCC[C@]12C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G12 compound treatment 4840.0 -1890.0 -0.81 3320.0 596.0 0.27 -0.3799 -0.4435 1000002 KBio2_000130 CCCCCCCCCCCCCC(=O)N[C@@H](C)[C@H](O)c1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G13 compound treatment 5000.0 -1730.0 -0.74 2240.0 -484.0 -0.22 -0.6824 -0.8803 98 KBio2_000131 C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)CCC3=C)/CCC[C@]12C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G14 compound treatment 5120.0 -1610.0 -0.69 2520.0 -204.0 -0.09 -0.5548 -0.7957 227 KBio2_000132 CCCCCCCC/C=C\C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G15 compound treatment 5520.0 -1210.0 -0.52 2720.0 -3.75 0.0 -0.3682 -0.7095 118 KBio2_000133 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OC(CO)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G16 compound treatment 4040.0 -2690.0 -1.16 2080.0 -644.0 -0.3 -1.0263 -0.8605 8 KBio2_000134 CCCCCCCC/C=C\C/C=C\C/C=C\CCCC(=O)NCCO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G17 compound treatment 5400.0 -1330.0 -0.57 2320.0 -404.0 -0.19 -0.5347 -0.8912 276 KBio2_000135 CCCCCCCCCCCCCCC(F)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G18 compound treatment 5280.0 -1450.0 -0.62 2440.0 -284.0 -0.13 -0.5322 -0.8372 136 KBio2_000136 COC(C)(C)CCCC(C)C/C=C/C(=C/C(=O)O)/C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G19 compound treatment 5560.0 -1170.0 -0.5 2720.0 -3.75 0.0 -0.356 -0.7095 274 KBio2_000137 CCCCCCCCCCCCC(O)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G20 compound treatment 6520.0 -207.0 -0.09 3080.0 356.0 0.16 0.053 0.2843 310 KBio2_000138 CCCCC(C)(O)C/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G21 compound treatment 5560.0 -1170.0 -0.5 2320.0 -404.0 -0.19 -0.4861 -0.9085 130 KBio2_000139 C/C(=C\C=C\C(=C\C(=O)Nc1ccc(O)cc1)\C)/C=C/C2=C(C)CCCC2(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G22 compound treatment 4640.0 -2090.0 -0.9 2840.0 116.0 0.05 -0.5968 -0.6638 309 KBio2_000140 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)N(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G23 mock treatment 5520.0 -1210.0 -0.52 2800.0 76.3 0.04 -0.3422 -0.6578 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 G24 mock treatment 160.0 -6570.0 -2.82 200.0 -2520.0 -1.16 -2.8175 -0.9228 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H01 mock treatment 7520.0 793.0 0.34 2440.0 -284.0 -0.13 0.149 0.4079 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H02 mock treatment 5680.0 -1050.0 -0.45 3720.0 996.0 0.46 0.0056 0.0088 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H03 compound treatment 5720.0 -1010.0 -0.43 3840.0 1120.0 0.51 0.0568 0.0846 119 KBio2_000141 OC(=O)c1ccccc1Nc2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H04 compound treatment 5040.0 -1690.0 -0.73 1840.0 -884.0 -0.41 -0.8003 -0.9625 556 KBio2_000142 COc1cc2ncc(nc2cc1OC)c3ccccc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H05 compound treatment 4920.0 -1810.0 -0.78 3240.0 516.0 0.24 -0.3816 -0.4696 3001877 KBio2_000143 OC(=O)c1cc(O)ccc1NCCCc2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H06 compound treatment 4080.0 -2650.0 -1.14 3200.0 476.0 0.22 -0.65 -0.5608 3001878 KBio2_000144 Cc1[nH]c(=O)c([N+]#[C-])cc1c2ccncc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H07 compound treatment 5520.0 -1210.0 -0.52 3040.0 316.0 0.15 -0.2641 -0.4901 2450 KBio2_000145 Oc1ccc(cc1n2c(=O)[nH]c3cc(ccc23)C(F)(F)F)C(F)(F)F 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H08 compound treatment 4280.0 -2450.0 -1.05 3080.0 356.0 0.16 -0.6282 -0.5899 2080829 KBio2_000146 OCC1(CO)N2CCC(CC2)C1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H09 compound treatment 5320.0 -1410.0 -0.6 2760.0 36.3 0.02 -0.416 -0.6874 124 KBio2_000147 CC(C)(O)[C@H]1O[C@H]2CC[C@]3(C)[C@]4(C)[C@H](Cc5c4[nH]c6ccccc56)CC[C@@]3(O)C2=CC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H10 compound treatment 160.0 -6570.0 -2.82 360.0 -2360.0 -1.09 -2.7655 -0.9139 1907753 KBio2_000148 CC[C@@H]1[C@H](C)C[C@@H]2[C@H]3C[C@H]4CCC(=O)C5=C(O)[C@H](CCCNC(=O)/C=C\C[C@@H]4[C@H]3C=C[C@@H]12)NC5=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H11 compound treatment 5720.0 -1010.0 -0.43 2880.0 156.0 0.07 -0.2553 -0.5818 126 KBio2_000149 CC1(C)Oc2ccc(C#N)cc2[C@@H](OC3=CC(=O)CC3)[C@@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H12 compound treatment 3800.0 -2930.0 -1.26 2800.0 76.3 0.04 -0.8652 -0.6871 354 KBio2_000150 Nc1ccc2C(=O)NC(=O)c3cccc1c32 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H13 compound treatment 2680.0 -4050.0 -1.74 1440.0 -1280.0 -0.59 -1.648 -0.8968 128 KBio2_000151 CC(=C)[C@H]1O[C@H]2CC[C@]3(C)[C@]4(C)[C@@H](CC[C@@]3(O)[C@@]52O[C@@H]5[C@H]1O)[C@@H]6OC(C)(C)[C@H]7C[C@@H]8C(=C)Cc9c(Cl)cc%10[nH]c4c6c%10c9[C@@]87O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H14 compound treatment 4280.0 -2450.0 -1.05 2120.0 -604.0 -0.28 -0.9403 -0.8641 445 KBio2_000152 NC(=O)c1cccc(N)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H15 compound treatment 3000.0 -3730.0 -1.6 1960.0 -764.0 -0.35 -1.3816 -0.8421 2474 KBio2_000153 Nc1nc(N)c(nc1Cl)C(=O)NC(=N)Nc2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H16 compound treatment 3280.0 -3450.0 -1.48 1760.0 -964.0 -0.44 -1.3615 -0.88 1907754 KBio2_000154 CO[C@H]1C[C@H](C)CC2=C(NCC=C)C(=O)C=C(NC(=O)/C(=C/C=C\[C@H](OC)[C@@H](OC(=O)N)/C(=C/[C@H](C)[C@H]1O)/C)/C)C2=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H17 compound treatment 3840.0 -2890.0 -1.24 1960.0 -764.0 -0.35 -1.1262 -0.8729 153 KBio2_000155 CC1=CC=C(CC1)N(CC2=NCCN2)c3cccc(O)c3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H18 compound treatment 680.0 -6050.0 -2.6 80.0 -2640.0 -1.22 -2.6984 -0.94 3001880 KBio2_000156 CC(=O)O[C@@H]1[C@@H](O)CN[C@@H]1Cc2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H19 compound treatment 5040.0 -1690.0 -0.73 2480.0 -244.0 -0.11 -0.5922 -0.8068 3001155 KBio2_000157 CC1(C)NC(=O)NC1=O.c1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H20 compound treatment 5320.0 -1410.0 -0.6 2120.0 -604.0 -0.28 -0.6241 -0.9376 154 KBio2_000158 C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H]1CC[C@H]3C[C@@H]4C[C@@]32CC[C@]4(O)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H21 compound treatment 400.0 -6330.0 -2.72 240.0 -2480.0 -1.14 -2.7315 -0.9257 156 KBio2_000159 Fc1ccc(cc1)C(CCCN2CCC(CC2)n3c(=O)[nH]c4ccccc34)c5ccc(F)cc5Cl 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H22 compound treatment 5760.0 -967.0 -0.42 2560.0 -164.0 -0.08 -0.3472 -0.8218 401 KBio2_000160 COc1cccc2c1cc([N+](=O)[O-])c3c(cc4OCOc4c23)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H23 mock treatment 6680.0 -46.7 -0.02 2720.0 -3.75 0.0 -0.0154 -0.765 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 H24 mock treatment 280.0 -6450.0 -2.77 120.0 -2600.0 -1.2 -2.807 -0.9295 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I01 mock treatment 7520.0 793.0 0.34 3160.0 436.0 0.2 0.3831 0.9679 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I02 mock treatment 4560.0 -2170.0 -0.93 4240.0 1520.0 0.7 -0.1659 -0.1426 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I03 compound treatment 6320.0 -407.0 -0.17 3280.0 556.0 0.26 0.0572 0.1846 299 KBio2_000161 CCCCCCCCCCOCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I04 compound treatment 6120.0 -607.0 -0.26 3520.0 796.0 0.37 0.0744 0.1655 184 KBio2_000162 CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SCC(NC(=O)C)C(=O)O)[C@@H](O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I05 compound treatment 5640.0 -1090.0 -0.47 3240.0 516.0 0.24 -0.1626 -0.3102 13 KBio2_000163 CCCCC/C=C\C/C=C\C/C=C\C=C\[C@@H](O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I06 compound treatment 6520.0 -207.0 -0.09 3680.0 956.0 0.44 0.2481 0.553 14 KBio2_000164 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I07 compound treatment 5520.0 -1210.0 -0.52 2680.0 -43.8 -0.02 -0.3812 -0.734 64 KBio2_000165 CCCCC/C=C\C/C=C\C/C=C\C=C\[C@H](CCCC(=O)O)OO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I08 compound treatment 5360.0 -1370.0 -0.59 2840.0 116.0 0.05 -0.3778 -0.6402 123 KBio2_000166 CCCCC/C=C\C/C=C\CCCCCCCC(=O)NCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I09 compound treatment 5000.0 -1730.0 -0.74 2760.0 36.3 0.02 -0.5133 -0.6911 137 KBio2_000167 CCCCC/C=C\C/C=C\C/C=C\CC1OC1CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I10 compound treatment 6800.0 73.3 0.03 3080.0 356.0 0.16 0.1381 0.828 40 KBio2_000168 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I11 compound treatment 5520.0 -1210.0 -0.52 2920.0 196.0 0.09 -0.3031 -0.5755 146 KBio2_000169 CCCCCC#CCC#CCC#CCC#CCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I12 compound treatment 5640.0 -1090.0 -0.47 2920.0 196.0 0.09 -0.2667 -0.5602 66 KBio2_000170 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I13 compound treatment 3680.0 -3050.0 -1.31 2280.0 -444.0 -0.2 -1.0708 -0.8075 144 KBio2_000171 CCCCCCCCC#CCC#CCC#CCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I14 compound treatment 5240.0 -1490.0 -0.64 2160.0 -564.0 -0.26 -0.6354 -0.921 69 KBio2_000172 CCCCCCCC/C=C\CCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I15 compound treatment 5080.0 -1650.0 -0.71 2560.0 -164.0 -0.08 -0.554 -0.7779 145 KBio2_000173 CCCCC/C=C\C/C=C\C/C=C\C=C\C(=O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I16 compound treatment 5040.0 -1690.0 -0.73 2760.0 36.3 0.02 -0.5011 -0.6907 318 KBio2_000174 CCCCCCCCCCCCCCCC(=O)NCCO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I17 compound treatment 5320.0 -1410.0 -0.6 1960.0 -764.0 -0.35 -0.6761 -0.9665 120 KBio2_000175 O=Cc1c2[nH]c3ccccc3c2cc4[nH]c5ccccc5c14 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I18 compound treatment 4640.0 -2090.0 -0.9 2880.0 156.0 0.07 -0.5838 -0.6484 114 KBio2_000176 CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)O)OC(=O)CCCCCCCCCCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I19 compound treatment 6040.0 -687.0 -0.3 2240.0 -484.0 -0.22 -0.3661 -0.9902 257 KBio2_000177 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC(=O)CCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I20 compound treatment 6800.0 73.3 0.03 3120.0 396.0 0.18 0.1511 0.8174 190 KBio2_000178 CCCCC[C@H](O)/C=C/[C@H]1C=CC(=O)[C@@H]1CCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I21 compound treatment 6160.0 -567.0 -0.24 3240.0 516.0 0.24 -0.0045 -0.0132 258 KBio2_000179 CCCCCCCCCCC/C=C\C(C)(C)/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I22 compound treatment 7160.0 433.0 0.19 3520.0 796.0 0.37 0.3907 0.9509 212 KBio2_000180 CCCCC[C@H](O)/C=C/[C@H]1C=CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I23 mock treatment 5240.0 -1490.0 -0.64 3240.0 516.0 0.24 -0.2843 -0.4168 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 I24 mock treatment 280.0 -6450.0 -2.77 120.0 -2600.0 -1.2 -2.807 -0.9295 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J01 mock treatment 7840.0 1110.0 0.48 3600.0 876.0 0.4 0.6235 0.9963 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J02 mock treatment 6120.0 -607.0 -0.26 3760.0 1040.0 0.48 0.1524 0.2806 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J03 compound treatment 6120.0 -607.0 -0.26 2800.0 76.3 0.04 -0.1597 -0.6066 3104408 KBio2_000181 CC(N/C(=N\C#N)/Nc1ccncc1)C(C)(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J04 compound treatment 5440.0 -1290.0 -0.55 3080.0 356.0 0.16 -0.2755 -0.4773 1907755 KBio2_000182 COCc1nc2n(CC(C)C)c(=O)n(C)c(=O)c2[nH]1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J05 compound treatment 6400.0 -327.0 -0.14 3600.0 876.0 0.4 0.1856 0.4349 2431 KBio2_000183 CCN(CC)CCNC(=O)c1ccc(N)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J06 compound treatment 120.0 -6610.0 -2.84 40.0 -2680.0 -1.23 -2.8817 -0.9303 1907756 KBio2_000184 Clc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J07 compound treatment 3920.0 -2810.0 -1.21 2280.0 -444.0 -0.2 -0.9978 -0.8151 3104409 KBio2_000185 CCCNCC(O)COc1ccccc1.CC(=O)CCc1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J08 compound treatment 4760.0 -1970.0 -0.85 3160.0 436.0 0.2 -0.4562 -0.5248 155 KBio2_000186 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC[C@@H](NC[C@@H](N)CS)C(C)C)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J09 compound treatment 5000.0 -1730.0 -0.74 2760.0 36.3 0.02 -0.5133 -0.6911 161 KBio2_000187 COc1ccc2nccc(C(O)[C@H]3CC4CC[C@@H]3CC4C=C)c2c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J10 compound treatment 4680.0 -2050.0 -0.88 2240.0 -484.0 -0.22 -0.7797 -0.8588 361 KBio2_000188 CC(C)(c1ccc(OCC2CO2)cc1)c3ccc(OCC4CO4)cc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J11 compound treatment 4040.0 -2690.0 -1.16 2240.0 -484.0 -0.22 -0.9743 -0.828 1000050 KBio2_000189 COc1ccc2nccc([C@@H](O)[C@@H]3CC4CC[C@@H]3CC4C=C)c2c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J12 compound treatment 4760.0 -1970.0 -0.85 3480.0 756.0 0.35 -0.3522 -0.3851 3103962 KBio2_000190 CO[C@H]1/C=C/C=C(\C)/C[C@@H](C)[C@H](O)[C@H](C)/C=C(\C)/C=C(\OC)/C(=O)O[C@@H]1[C@@H](C)[C@@H](O)[C@H](C)[C@H]2C[C@@H](O)[C@H](C)[C@H](O2)C(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J13 compound treatment 5640.0 -1090.0 -0.47 3160.0 436.0 0.2 -0.1886 -0.3709 907369 KBio2_000191 CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J14 compound treatment 960.0 -5770.0 -2.48 440.0 -2280.0 -1.05 -2.4962 -0.9268 3103963 KBio2_000192 CC(=O)OCOC(=O)CNc1ccccc1OCCOc2ccccc2NCC(=O)OCOC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J15 compound treatment 5240.0 -1490.0 -0.64 2760.0 36.3 0.02 -0.4403 -0.6884 3103964 KBio2_000193 CC(C)[C@]1(O)[C@@H](OC(=O)c2ccc[nH]2)[C@]3(O)[C@]4(O)[C@]1(C)[C@]5(O)C[C@@]3(C)[C@@]6(O)CC[C@H](C)[C@@H](O)[C@]46O5 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J16 compound treatment 4520.0 -2210.0 -0.95 1960.0 -764.0 -0.35 -0.9194 -0.9086 3103618 KBio2_000194 Cc1ccc2N=C3N(CCC3(O)C(=O)c2c1)c4ccccc4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J17 compound treatment 4240.0 -2490.0 -1.07 2080.0 -644.0 -0.3 -0.9655 -0.8701 165 KBio2_000195 OC(COc1cccc2[nH]c(C#N)cc12)CN3CCN(CC3)C(c4ccccc4)c5ccccc5 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J18 compound treatment 6120.0 -607.0 -0.26 2480.0 -244.0 -0.11 -0.2637 -0.9288 3001881 KBio2_000196 */C=C(/CC(=O)O)\C=C\[C@@H](C)C\C=C\CC/C=C/C=C\CC/C(=C\C=C(\*)/C)/C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J19 compound treatment 1360.0 -5370.0 -2.31 680.0 -2040.0 -0.94 -2.2965 -0.9216 390 KBio2_000197 COc1ccc(CCCOC(Cn2ccnc2)c3ccc(OC)cc3)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J20 compound treatment 5080.0 -1650.0 -0.71 2520.0 -204.0 -0.09 -0.567 -0.7937 1000439 KBio2_000198 CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4ccc(I)cc4)ncnc23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J21 compound treatment 2960.0 -3770.0 -1.62 1320.0 -1400.0 -0.65 -1.6019 -0.9186 193 KBio2_000199 COc1cc2CCN(C)[C@H]3Cc4ccc(OC)c(Oc5ccc(C[C@@H]6N(C)CCc7cc(OC)c(Oc(c1OC)c32)cc67)cc5)c4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J22 compound treatment 5120.0 -1610.0 -0.69 2000.0 -724.0 -0.33 -0.7239 -0.9439 3104702 KBio2_000200 C[C@H]1CCC/C=C/C2C[C@H](O)C[C@H]2[C@H](O)/C=C/C(=O)O1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J23 mock treatment 5920.0 -807.0 -0.35 2840.0 116.0 0.05 -0.2075 -0.5912 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 J24 mock treatment 200.0 -6530.0 -2.81 40.0 -2680.0 -1.23 -2.8574 -0.9319 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K01 mock treatment 6880.0 153.0 0.07 4280.0 1560.0 0.72 0.5526 0.769 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K02 mock treatment 7400.0 673.0 0.29 4120.0 1400.0 0.64 0.6587 0.9353 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K03 compound treatment 4560.0 -2170.0 -0.93 4480.0 1760.0 0.81 -0.0879 -0.0713 139 KBio2_000201 CCCCC/C=C\C/C=C\CC1OC1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K04 compound treatment 5760.0 -967.0 -0.42 4400.0 1680.0 0.77 0.251 0.2867 214 KBio2_000202 CCCCC[C@H](O)/C=C/C1=C(CCCCCCC(=O)O)C(=O)CC1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K05 compound treatment 7160.0 433.0 0.19 4080.0 1360.0 0.62 0.5727 0.88 1000033 KBio2_000203 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@H]1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K06 compound treatment 5040.0 -1690.0 -0.73 3680.0 956.0 0.44 -0.202 -0.2382 216 KBio2_000204 CCCCC[C@H](O)/C=C/C1=C(C/C=C\CCCC(=O)O)C(=O)CC1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K07 compound treatment 5440.0 -1290.0 -0.55 2760.0 36.3 0.02 -0.3795 -0.6855 57 KBio2_000205 CCCCC/C=C\C=C\[C@@H](O)CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K08 compound treatment 5640.0 -1090.0 -0.47 2800.0 76.3 0.04 -0.3057 -0.6522 218 KBio2_000206 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@@H](O)CC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K09 compound treatment 4880.0 -1850.0 -0.79 2760.0 36.3 0.02 -0.5498 -0.6921 88 KBio2_000207 CCCCC/C=C\C=C\[C@H](CCCCCCCC(=O)O)OO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K10 compound treatment 6360.0 -367.0 -0.16 3280.0 556.0 0.26 0.0694 0.2308 220 KBio2_000208 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K11 compound treatment 5400.0 -1330.0 -0.57 2480.0 -244.0 -0.11 -0.4827 -0.8301 45 KBio2_000209 CCCCCCCC/C=C\CCCCCCCC(=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K12 compound treatment 6960.0 233.0 0.1 3560.0 836.0 0.38 0.3429 0.8627 222 KBio2_000210 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K13 compound treatment 4560.0 -2170.0 -0.93 2400.0 -324.0 -0.15 -0.7642 -0.8098 1000028 KBio2_000211 CCCCC[C@H](O)/C=C/[C@H]1[C@@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K14 compound treatment 4640.0 -2090.0 -0.9 2160.0 -564.0 -0.26 -0.8179 -0.8756 226 KBio2_000212 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K15 compound treatment 5600.0 -1130.0 -0.48 2720.0 -3.75 0.0 -0.3438 -0.7096 1000027 KBio2_000213 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H](O)[C@@H]1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K16 compound treatment 6160.0 -567.0 -0.24 2040.0 -684.0 -0.31 -0.3946 -0.9921 224 KBio2_000214 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K17 compound treatment 3000.0 -3730.0 -1.6 1400.0 -1320.0 -0.61 -1.5637 -0.9121 1000008 KBio2_000215 C/C(=C/C=C/C(=C/C(=O)O)/C)/C=C/C1=C(C)CCCC1(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K18 compound treatment 4960.0 -1770.0 -0.76 2080.0 -644.0 -0.3 -0.7466 -0.9156 3184 KBio2_000216 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H]2O/C(=C\CCCC(=O)O)/C[C@H]12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K19 compound treatment 4560.0 -2170.0 -0.93 2800.0 76.3 0.04 -0.6341 -0.68 47 KBio2_000217 CC(=CCC/C(=C/CC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)/C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K20 compound treatment 5960.0 -767.0 -0.33 2680.0 -43.8 -0.02 -0.2474 -0.7489 267 KBio2_000218 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K21 compound treatment 5160.0 -1570.0 -0.67 2760.0 36.3 0.02 -0.4646 -0.6894 266 KBio2_000219 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K22 compound treatment 4160.0 -2570.0 -1.1 1520.0 -1200.0 -0.55 -1.1719 -0.949 104 KBio2_000220 C/C(=C\C=C\C(=C\C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K23 mock treatment 6680.0 -46.7 -0.02 2720.0 -3.75 0.0 -0.0154 -0.765 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 K24 mock treatment 200.0 -6530.0 -2.81 240.0 -2480.0 -1.14 -2.7924 -0.9215 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L01 mock treatment 7240.0 513.0 0.22 3280.0 556.0 0.26 0.337 0.9973 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L02 mock treatment 6560.0 -167.0 -0.07 3440.0 716.0 0.33 0.1822 0.5406 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L03 compound treatment 2040.0 -4690.0 -2.02 1280.0 -1440.0 -0.66 -1.8947 -0.8928 194 KBio2_000221 CCCCCCCC(=O)O[C@@H]1[C@@H](OC(=O)/C(=C\C)/C)C(=C2[C@@H]3OC(=O)[C@@](C)(O)[C@@]3(O)[C@H](C[C@](C)(OC(=O)C)[C@@H]12)OC(=O)CCC)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L04 compound treatment 6040.0 -687.0 -0.3 2960.0 236.0 0.11 -0.132 -0.4195 407 KBio2_000222 [O-][N+](=O)c1cccc2c(Br)n[nH]c12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L05 compound treatment 6920.0 193.0 0.08 1640.0 -1080.0 -0.5 -0.2936 -0.5811 392 KBio2_000223 CCN(CC)CCCCCCCOC(=O)c1cc(OC)c(OC)c(OC)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L06 compound treatment 5960.0 -767.0 -0.33 3120.0 396.0 0.18 -0.1043 -0.2769 3103965 KBio2_000224 Nc1ncnc2n(C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3O)c(Br)nc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L07 compound treatment 4840.0 -1890.0 -0.81 3000.0 276.0 0.13 -0.4839 -0.5892 196 KBio2_000225 Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CCCCCC2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L08 compound treatment 5080.0 -1650.0 -0.71 2560.0 -164.0 -0.08 -0.554 -0.7779 3103966 KBio2_000226 NC1=NC2C(N=C(Br)N2C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3O)C(=O)N1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L09 compound treatment 5880.0 -847.0 -0.36 3240.0 516.0 0.24 -0.0896 -0.2062 198 KBio2_000227 CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L10 compound treatment 6240.0 -487.0 -0.21 3160.0 436.0 0.2 -0.0062 -0.0212 404 KBio2_000228 CCCCNc1cc(cc(c1Oc2ccccc2)S(=O)(=O)N)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L11 compound treatment 6800.0 73.3 0.03 3360.0 636.0 0.29 0.2292 0.7788 3103746 KBio2_000229 C1CCC(CC1)/N=C(\NC2C3CC4CC(C3)CC2C4)/N5CCOCC5 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L12 compound treatment 5680.0 -1050.0 -0.45 2720.0 -3.75 0.0 -0.3195 -0.7098 3001884 KBio2_000230 CCNC(=O)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)n2cnc3c(N)ncnc23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L13 compound treatment 5360.0 -1370.0 -0.59 2320.0 -404.0 -0.19 -0.5469 -0.8872 396 KBio2_000231 CN([C@H]1CCCC[C@@H]1N2CCCC2)C(=O)Cc3ccc(Cl)c(Cl)c3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L14 compound treatment 800.0 -5930.0 -2.55 520.0 -2200.0 -1.01 -2.5189 -0.9183 373 KBio2_000232 CC(/C=C/c1cccc(Oc2ccc(F)cc2)c1)N(O)C(=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L15 compound treatment 6480.0 -247.0 -0.11 2480.0 -244.0 -0.11 -0.1543 -0.9996 1000056 KBio2_000233 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L16 compound treatment 6080.0 -647.0 -0.28 2720.0 -3.75 0.0 -0.1979 -0.7115 3103967 KBio2_000234 CCCNC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N2CCC[C@H]2C(=O)OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L17 compound treatment 6200.0 -527.0 -0.23 2800.0 76.3 0.04 -0.1354 -0.5906 200 KBio2_000235 COc1ccc(cc1OC)C(=O)OC2CC[C@@]3(C)C4CCC5[C@@]3(C[C@@]6(O)C7CN8CC(C)CCC8[C@@](C)(O)[C@@]7(O)[C@@H](O)C[C@@]56O)O[C@@]42O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L18 compound treatment 4280.0 -2450.0 -1.05 1560.0 -1160.0 -0.54 -1.1224 -0.9508 1907757 KBio2_000236 Oc1ccc(NC2=C(C(=O)NC2=O)c3ccccc3[N+](=O)[O-])cc1Cl 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L19 compound treatment 5280.0 -1450.0 -0.62 2760.0 36.3 0.02 -0.4282 -0.6879 202 KBio2_000237 COc1ccc(CCN(C)CCc2ccc(OC)c(OC)c2)cc1OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L20 compound treatment 3320.0 -3410.0 -1.47 1720.0 -1000.0 -0.46 -1.3623 -0.8869 3103968 KBio2_000238 CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L21 compound treatment 5000.0 -1730.0 -0.74 2040.0 -684.0 -0.31 -0.7474 -0.9268 3104544 KBio2_000239 CC(O)(C(=O)Nc1ccccc1)C(F)(F)F.CS(=O)(=O)c1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L22 compound treatment 2800.0 -3930.0 -1.69 2120.0 -604.0 -0.28 -1.3904 -0.8124 125 KBio2_000240 COc1cc(O)c2c(=O)c(OC)c(CC(C)OC(=O)Oc3ccc(O)cc3)c4c5c(CC(C)OC(=O)c6ccccc6)c(OC)c(=O)c7c(O)cc(OC)c(c1c24)c75 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L23 mock treatment 6040.0 -687.0 -0.3 3080.0 356.0 0.16 -0.093 -0.2754 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 L24 mock treatment 320.0 -6410.0 -2.76 200.0 -2520.0 -1.16 -2.7689 -0.9261 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M01 mock treatment 9520.0 2790.0 1.2 4040.0 1320.0 0.61 1.2774 0.9496 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M02 mock treatment 6320.0 -407.0 -0.17 4200.0 1480.0 0.68 0.3563 0.5083 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M03 compound treatment 3680.0 -3050.0 -1.31 4000.0 1280.0 0.59 -0.5116 -0.3563 53 KBio2_000241 CC(=CCC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M04 compound treatment 7600.0 873.0 0.38 4080.0 1360.0 0.62 0.7066 0.9705 189 KBio2_000242 CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M05 compound treatment 5960.0 -767.0 -0.33 4520.0 1800.0 0.83 0.3509 0.3945 51 KBio2_000243 CC(=CCC/C(=C/CC/C(=C/CC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)/C)/C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M06 compound treatment 5000.0 -1730.0 -0.74 3240.0 516.0 0.24 -0.3572 -0.4582 49 KBio2_000244 COC(=O)[C@@H](N)CSC/C=C(\C)/CC/C=C(\C)/CCC=C(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M07 compound treatment 5320.0 -1410.0 -0.6 3600.0 876.0 0.4 -0.1429 -0.1966 116 KBio2_000245 Cc1c(nn(c1c2ccc(I)cc2)c3ccc(Cl)cc3Cl)C(=O)NN4CCCCC4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M08 compound treatment 5400.0 -1330.0 -0.57 2920.0 196.0 0.09 -0.3396 -0.588 1000032 KBio2_000246 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M09 compound treatment 6000.0 -727.0 -0.31 2640.0 -83.8 -0.04 -0.2482 -0.7883 132 KBio2_000247 CC1(C)CCC(C)(C)c2cc(ccc21)C(=O)Nc3ccc(cc3)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M10 compound treatment 6040.0 -687.0 -0.3 2960.0 236.0 0.11 -0.132 -0.4195 3103969 KBio2_000248 OC(=O)CCC/C=C\CC1C(CNNC(=O)Nc2ccccc2)C3CCC1O3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M11 compound treatment 4720.0 -2010.0 -0.86 2640.0 -83.8 -0.04 -0.6375 -0.7379 2 KBio2_000249 CCCCC/C=C\C/C=C\CCCCCCCC(=O)NCCO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M12 compound treatment 4080.0 -2650.0 -1.14 2600.0 -124.0 -0.06 -0.8451 -0.7415 3001885 KBio2_000250 CCCCCc1cc(O)c2C3C=C(CC[C@H]3C(C)(C)Oc2c1)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M13 compound treatment 5000.0 -1730.0 -0.74 2720.0 -3.75 0.0 -0.5263 -0.7087 4 KBio2_000251 CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)NCCO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M14 compound treatment 5040.0 -1690.0 -0.73 2240.0 -484.0 -0.22 -0.6702 -0.8833 134 KBio2_000252 C/C(=C\c1ccc(cc1)C(=O)O)/c2ccc3c(c2)C(C)(C)CCC3(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M15 compound treatment 4880.0 -1850.0 -0.79 2240.0 -484.0 -0.22 -0.7189 -0.8716 316 KBio2_000253 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M16 compound treatment 8960.0 2230.0 0.96 3200.0 476.0 0.22 0.834 0.8466 261 KBio2_000254 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@H]2CO[C@@H]1C2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M17 compound treatment 4920.0 -1810.0 -0.78 2800.0 76.3 0.04 -0.5246 -0.6745 6 KBio2_000255 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)NCCO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M18 compound treatment 4880.0 -1850.0 -0.79 2680.0 -43.8 -0.02 -0.5758 -0.7248 3103970 KBio2_000256 CCCCC/C=C\CC(O)/C=C/c1cccc(CC(O)CCCCO)n1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M19 compound treatment 5880.0 -847.0 -0.36 3440.0 716.0 0.33 -0.0246 -0.0501 20 KBio2_000257 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M20 compound treatment 5960.0 -767.0 -0.33 2480.0 -244.0 -0.11 -0.3124 -0.8971 18 KBio2_000258 Cc1c(C(=O)c2ccc3ccccc3c2)c4cccc5OC[C@@H](CN6CCOCC6)n1c54 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M21 compound treatment 5560.0 -1170.0 -0.5 3200.0 476.0 0.22 -0.1999 -0.3652 225 KBio2_000259 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M22 compound treatment 5800.0 -927.0 -0.4 3480.0 756.0 0.35 -0.0359 -0.0679 138 KBio2_000260 Cc1cccc(Nc2cc(Cl)nc(SCC(=O)O)n2)c1C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M23 mock treatment 6160.0 -567.0 -0.24 3400.0 676.0 0.31 0.0475 0.1204 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 M24 mock treatment 200.0 -6530.0 -2.81 120.0 -2600.0 -1.2 -2.8314 -0.9278 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N01 mock treatment 7760.0 1030.0 0.44 4200.0 1480.0 0.68 0.7942 0.9789 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N02 mock treatment 5760.0 -967.0 -0.42 4320.0 1600.0 0.73 0.225 0.2668 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N03 compound treatment 160.0 -6570.0 -2.82 80.0 -2640.0 -1.22 -2.8565 -0.9291 1002014 KBio2_000261 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)CCl 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N04 compound treatment 160.0 -6570.0 -2.82 80.0 -2640.0 -1.22 -2.8565 -0.9291 3103971 KBio2_000262 COC[C@H]([C@@H](O)[C@@H](O)C(=O)NCC[C@@H](C)c1nc(/C=C/C[C@H]2OC3(C[C@H](O)[C@H]2C)OC([C@@H](C[C@@H](O)[C@@H](C)[C@@H](O)[C@@H](C)/C=C(\C)/C(=C/C=C/C(=C\C#N)/C)/C)OC)[C@@H](OP(=O)(O)O)C3(C)C)co1)N(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N05 compound treatment 7160.0 433.0 0.19 3480.0 756.0 0.35 0.3777 0.9573 2041 KBio2_000263 OC(=O)CNC(=O)C(CS)Cc1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N06 compound treatment 200.0 -6530.0 -2.81 120.0 -2600.0 -1.2 -2.8314 -0.9278 3001887 KBio2_000264 CC[C@@]1(O)C(=O)OCc2c1cc3Cc4nc5ccccc5cc4-n3c2=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N07 compound treatment 5120.0 -1610.0 -0.69 3520.0 796.0 0.37 -0.2297 -0.2937 831924 KBio2_000265 O=C[C@@H]1CCCN1C(=O)[C@@H]2CCCN2C(=O)OCc3ccccc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N08 compound treatment 240.0 -6490.0 -2.79 80.0 -2640.0 -1.22 -2.8322 -0.9307 363 KBio2_000266 CC12C3CCC(O3)C2(C)C(=O)OC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N09 compound treatment 2560.0 -4170.0 -1.79 1560.0 -1160.0 -0.54 -1.6455 -0.8799 1907758 KBio2_000267 CCC(C)[C@H](NS(=O)(=O)c1cccc2ccccc12)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N10 compound treatment 3920.0 -2810.0 -1.21 2440.0 -284.0 -0.13 -0.9458 -0.779 446 KBio2_000268 COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N11 compound treatment 160.0 -6570.0 -2.82 160.0 -2560.0 -1.18 -2.8305 -0.9249 1891 KBio2_000269 Clc1oc(=O)c2ccccc2c1Cl 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N12 compound treatment 1640.0 -5090.0 -2.19 720.0 -2000.0 -0.92 -2.1984 -0.9261 377 KBio2_000270 Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc3ccc(Cl)cc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N13 compound treatment 6200.0 -527.0 -0.23 240.0 -2480.0 -1.14 -0.9677 -0.8312 1907759 KBio2_000271 CC(C)[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)OC(C)(C)C)C(C)C)C=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N14 compound treatment 5360.0 -1370.0 -0.59 2720.0 -3.75 0.0 -0.4168 -0.7092 379 KBio2_000272 O[C@H]1CCN2C[C@H](O)[C@@H](O)[C@H](O)[C@@H]12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N15 compound treatment 6440.0 -287.0 -0.12 3000.0 276.0 0.13 0.0026 0.0149 2060 KBio2_000273 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N16 compound treatment 3920.0 -2810.0 -1.21 2000.0 -724.0 -0.33 -1.0888 -0.8696 3103975 KBio2_000274 CCCN(CCC)c1nc(N2CCCCC2)c3nc(nc(N4CCCCC4)c3n1)N(CCC)CCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N17 compound treatment 3080.0 -3650.0 -1.57 2600.0 -124.0 -0.06 -1.1492 -0.7323 1907760 KBio2_000275 C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)CCl 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N18 compound treatment 2360.0 -4370.0 -1.88 1320.0 -1400.0 -0.65 -1.7843 -0.8985 391 KBio2_000276 Clc1ccc2NC(=O)CSC(c3ccccc3Cl)c2c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N19 compound treatment 3760.0 -2970.0 -1.28 2480.0 -244.0 -0.11 -0.9814 -0.7663 1907761 KBio2_000277 CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc2ccccc2)C=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N20 compound treatment 40.0 -6690.0 -2.88 80.0 -2640.0 -1.22 -2.893 -0.9266 3001890 KBio2_000278 COc1ccc2c(c1)c(OC)[n+](C)c3c2ccc4cc5OCOc5cc43 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N21 compound treatment 2080.0 -4650.0 -2.0 1040.0 -1680.0 -0.77 -1.9605 -0.9148 1907762 KBio2_000279 CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C)C=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N22 compound treatment 1760.0 -4970.0 -2.14 920.0 -1800.0 -0.83 -2.0969 -0.9151 1907763 KBio2_000280 Oc1ccc(/C=C/C(=O)OCCc2ccccc2)cc1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N23 mock treatment 7160.0 433.0 0.19 3160.0 436.0 0.2 0.2736 0.9993 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 N24 mock treatment 520.0 -6210.0 -2.67 120.0 -2600.0 -1.2 -2.7341 -0.9346 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O01 mock treatment 7160.0 433.0 0.19 4360.0 1640.0 0.75 0.6638 0.8564 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O02 mock treatment 7240.0 513.0 0.22 4520.0 1800.0 0.83 0.7401 0.8657 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O03 compound treatment 5040.0 -1690.0 -0.73 3680.0 956.0 0.44 -0.202 -0.2382 73 KBio2_000281 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O04 compound treatment 5240.0 -1490.0 -0.64 3040.0 316.0 0.15 -0.3493 -0.5327 338 KBio2_000282 Nc1ccncc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O05 compound treatment 5880.0 -847.0 -0.36 3480.0 756.0 0.35 -0.0116 -0.023 12 KBio2_000283 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)N4CCOCC4)c2c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O06 compound treatment 5120.0 -1610.0 -0.69 4080.0 1360.0 0.62 -0.0476 -0.0512 340 KBio2_000284 CCCCCC(O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O07 compound treatment 6360.0 -367.0 -0.16 3040.0 316.0 0.15 -0.0087 -0.0405 305 KBio2_000285 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O08 compound treatment 5920.0 -807.0 -0.35 2960.0 236.0 0.11 -0.1685 -0.4635 1000039 KBio2_000286 CC[C@]1(COC)[C@H](O)C[C@H](OC)[C@@]2(C(C)C)C3C[C@@]4(O)[C@H](OC(=O)c5ccccc5)C3[C@](C[C@H](OC)C12)(OC(=O)C)[C@@H](O)C[C@@H]4OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O09 compound treatment 6240.0 -487.0 -0.21 2680.0 -43.8 -0.02 -0.1622 -0.7715 307 KBio2_000287 CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O10 compound treatment 2320.0 -4410.0 -1.9 1600.0 -1120.0 -0.52 -1.7055 -0.8682 24 KBio2_000288 CN(CCc1ccc(Cl)c(Cl)c1)CC(O)COc2ccc(NS(=O)(=O)C)cc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O11 compound treatment 5360.0 -1370.0 -0.59 3120.0 396.0 0.18 -0.2868 -0.466 311 KBio2_000289 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O12 compound treatment 4600.0 -2130.0 -0.91 2680.0 -43.8 -0.02 -0.661 -0.7225 1000040 KBio2_000290 [N-2]C1(CC2CC3CC(C2)C1)C3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O13 compound treatment 5120.0 -1610.0 -0.69 3200.0 476.0 0.22 -0.3337 -0.4604 313 KBio2_000291 CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(=O)CCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O14 compound treatment 5880.0 -847.0 -0.36 2040.0 -684.0 -0.31 -0.4798 -0.9973 1000042 KBio2_000292 NC(=N)NC(=O)c1nc(Cl)c(N)nc1N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O15 compound treatment 5080.0 -1650.0 -0.71 2520.0 -204.0 -0.09 -0.567 -0.7937 271 KBio2_000293 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H]2C/C(=C\CCCC(=O)O)/C[C@H]12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O16 compound treatment 2160.0 -4570.0 -1.96 1240.0 -1480.0 -0.68 -1.8712 -0.9 26 KBio2_000294 CCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O17 compound treatment 5600.0 -1130.0 -0.48 2360.0 -364.0 -0.17 -0.4609 -0.8991 140 KBio2_000295 CC1(COc2ccc(CC3SC(=O)NC3=O)cc2)CCCCC1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O18 compound treatment 320.0 -6410.0 -2.76 40.0 -2680.0 -1.23 -2.8209 -0.9344 28 KBio2_000296 CNc1ccc2oc(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)c5ccc[nH]5)[C@H](C)C[C@H]4C)nc2c1C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O19 compound treatment 4760.0 -1970.0 -0.85 2320.0 -404.0 -0.19 -0.7293 -0.8423 142 KBio2_000297 CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O20 compound treatment 2280.0 -4450.0 -1.91 1240.0 -1480.0 -0.68 -1.8347 -0.9036 3103889 KBio2_000298 COC(=O)C1=C(C)NC(=C(O)C1c2ccccc2C(F)(F)F)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O21 compound treatment 5760.0 -967.0 -0.42 3000.0 276.0 0.13 -0.2041 -0.4696 219 KBio2_000299 O[C@@H](COc1cccc(Cl)c1)/C=C/[C@H]2[C@H](O)C[C@H](O)[C@@H]2C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O22 compound treatment 8200.0 1470.0 0.63 3280.0 556.0 0.26 0.6289 0.9204 3103678 KBio2_000300 N/C(=N\C(=O)c1nc(Cl)c(N)nc1N)/NCc2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O23 mock treatment 6000.0 -727.0 -0.31 3080.0 356.0 0.16 -0.1052 -0.298 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 O24 mock treatment 240.0 -6490.0 -2.79 80.0 -2640.0 -1.22 -2.8322 -0.9307 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P01 mock treatment 8600.0 1870.0 0.81 3440.0 716.0 0.33 0.8026 0.9221 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P02 mock treatment 5560.0 -1170.0 -0.5 4280.0 1560.0 0.72 0.1512 0.173 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P03 compound treatment 6320.0 -407.0 -0.17 4720.0 2000.0 0.92 0.5254 0.5623 1907764 KBio2_000301 CCCC[C@@H]1[C@@H](OC(=O)CC(C)C)[C@H](C)OC(=O)[C@@H](NC(=O)c2cccc(NC=O)c2OC)[C@@H](C)OC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P04 compound treatment 7840.0 1110.0 0.48 4400.0 1680.0 0.77 0.8836 0.9738 393 KBio2_000302 CC(C)NCC(O)c1ccc(N)c(C#N)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P05 compound treatment 960.0 -5770.0 -2.48 800.0 -1920.0 -0.88 -2.3792 -0.9036 2090 KBio2_000303 CCOC(=O)C(C#N)C1C(=C(N)Oc2ccc(Br)cc12)C(=O)OCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P06 compound treatment 5840.0 -887.0 -0.38 3560.0 836.0 0.38 0.0023 0.0042 157 KBio2_000304 COC(=O)CC[C@H](NC(=O)CNC(=O)c1ccc(/C=C/C(=O)OC)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P07 compound treatment 4000.0 -2730.0 -1.17 3280.0 556.0 0.26 -0.6483 -0.5402 2020 KBio2_000305 CCCCCCCCCCC1=C(C)C(=O)C(=C(OC)C1=O)OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P08 compound treatment 5400.0 -1330.0 -0.57 3000.0 276.0 0.13 -0.3136 -0.5365 395 KBio2_000306 C(Oc1ccccc1C2CC2)C3=NCCN3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P09 compound treatment 3080.0 -3650.0 -1.57 1480.0 -1240.0 -0.57 -1.5134 -0.9066 3103891 KBio2_000307 CC(=C)C1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P10 compound treatment 6280.0 -447.0 -0.19 2400.0 -324.0 -0.15 -0.2411 -0.9921 448 KBio2_000308 Clc1cccc(Cl)c1N=C2NCCN2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P11 compound treatment 3960.0 -2770.0 -1.19 2760.0 36.3 0.02 -0.8296 -0.6971 1000476 KBio2_000309 C[C@@H](N(C)CC#C)c1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P12 compound treatment 3480.0 -3250.0 -1.4 2400.0 -324.0 -0.15 -1.0926 -0.7781 417 KBio2_000310 CN1CCN(CC1)C2=Nc3cc(Cl)ccc3Nc4ccccc24 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P13 compound treatment 3720.0 -3010.0 -1.29 2720.0 -3.75 0.0 -0.9156 -0.708 410 KBio2_000311 CC(=N)NCc1cccc(CN)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P14 compound treatment 1240.0 -5490.0 -2.36 1000.0 -1720.0 -0.79 -2.229 -0.8955 3001893 KBio2_000312 COc1ccc(/C=C/C(=O)CC(=O)\C=C\c2cccc(O)c2OC)cc1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P15 compound treatment 5000.0 -1730.0 -0.74 3200.0 476.0 0.22 -0.3702 -0.4782 3001894 KBio2_000313 *[C@@H](C[C@@H](C)C[C@H](O)CCCC[C@@H](O)C[C@H](O)[C@H](C)N)[C@H](*)[C@H](C)CCCC.CC(=O)C[C@@H](CC(=O)O)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P16 compound treatment 80.0 -6650.0 -2.86 120.0 -2600.0 -1.2 -2.8679 -0.9254 421 KBio2_000314 C[C@H]1C[C@H](C)C(=O)[C@@H](C1)[C@@H](O)CC2CC(=O)NC(=O)C2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P17 compound treatment 120.0 -6610.0 -2.84 80.0 -2640.0 -1.22 -2.8687 -0.9282 2340 KBio2_000315 CC(C)[C@@]12O[C@H]2[C@@H]3O[C@]34[C@]5(O[C@H]5C[C@H]6C7=C(CC[C@@]64C)C(=O)OC7)[C@@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P18 compound treatment 3800.0 -2930.0 -1.26 2160.0 -564.0 -0.26 -1.0733 -0.8352 3001895 KBio2_000316 *C1N(C)C(=O)C(*)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C(=O)C(CC)NC(=O)C(C(O)C(C)C/C=C/C)N(C)C(=O)C(*)N(C)C1=O)C(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P19 compound treatment 3920.0 -2810.0 -1.21 2840.0 116.0 0.05 -0.8157 -0.6751 1907765 KBio2_000317 Cc1coc-2c1C(=O)C(=O)c3c4CCCC(C)(C)c4ccc23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P20 compound treatment 4920.0 -1810.0 -0.78 2800.0 76.3 0.04 -0.5246 -0.6745 397 KBio2_000318 CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)c2cccc(Oc3ccccc3)c2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P21 compound treatment 520.0 -6210.0 -2.67 280.0 -2440.0 -1.12 -2.682 -0.9261 3103893 KBio2_000319 C[C@H]([C@@H]1O[C@@H](C[C@@H]2CC[C@@H](C)[C@@]3(O[C@@](C)(C[C@H]3C)[C@H]4CC[C@](C)(O4)[C@@H]5O[C@H](C[C@@H]5C)[C@H]6O[C@@](O)(CO)[C@H](C)C[C@@H]6C)O2)CC[C@@H]1C)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P22 compound treatment 6240.0 -487.0 -0.21 3680.0 956.0 0.44 0.1629 0.3345 3103894 KBio2_000320 C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@@]42OC(=O)/C=C/[C@H](O)CCC[C@@H](C)C\C=C\[C@H]4[C@H](O)C1=C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P23 mock treatment 6200.0 -527.0 -0.23 3840.0 1120.0 0.51 0.2028 0.3614 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.1464 P24 mock treatment 280.0 -6450.0 -2.77 120.0 -2600.0 -1.2 -2.807 -0.9295 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A01 mock treatment 7320.0 4950.0 2.13 7400.0 2960.0 1.36 2.4672 0.9765 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A02 mock treatment 6600.0 4230.0 1.82 5360.0 917.0 0.42 1.585 0.8485 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A03 compound treatment 5840.0 3470.0 1.49 6840.0 2400.0 1.1 1.8351 0.9889 315 Bio2_000481 CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)/C=C/CCCCCCCCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A04 compound treatment 5600.0 3230.0 1.39 4640.0 197.0 0.09 1.0468 0.7517 85 Bio2_000482 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)NC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A05 compound treatment 4960.0 2590.0 1.11 4600.0 157.0 0.07 0.8392 0.7515 29 Bio2_000483 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NCCCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A06 compound treatment 6080.0 3710.0 1.6 4600.0 157.0 0.07 1.1798 0.7384 302 Bio2_000484 CCCCC[C@H](O)C/C=C/1\[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A07 compound treatment 4800.0 2430.0 1.05 3800.0 -643.0 -0.3 0.5304 0.4882 10 Bio2_000485 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N[C@H](C)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A08 compound treatment 4480.0 2110.0 0.91 3960.0 -483.0 -0.22 0.4851 0.519 262 Bio2_000486 CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A09 compound treatment 4360.0 1990.0 0.86 4960.0 517.0 0.24 0.7737 0.8706 100 Bio2_000487 C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)C[C@H](O)C3=C)/CCC[C@]12C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A10 compound treatment 4600.0 2230.0 0.96 3960.0 -483.0 -0.22 0.5216 0.5296 1000034 Bio2_000488 CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A11 compound treatment 3800.0 1430.0 0.62 4360.0 -82.6 -0.04 0.4084 0.6622 148 Bio2_000489 CCCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A12 compound treatment 3360.0 991.0 0.43 3200.0 -1240.0 -0.57 -0.1026 -0.1439 122 Bio2_000490 C(c1c[nH]c2ccccc12)c3c[nH]c4ccccc34 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A13 compound treatment 2760.0 391.0 0.17 3800.0 -643.0 -0.3 -0.09 -0.2647 150 Bio2_000491 CCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A14 compound treatment 3440.0 1070.0 0.46 4600.0 157.0 0.07 0.3769 0.8083 31 Bio2_000492 CCCCCCCCCCCCCCC[C@H](O)[C@@H](N)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A15 compound treatment 3360.0 991.0 0.43 4640.0 197.0 0.09 0.3656 0.8389 171 Bio2_000493 CCCCCCCC/C=C\CCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCC/C=C\CCCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A16 compound treatment 3520.0 1150.0 0.5 3920.0 -523.0 -0.24 0.1802 0.3274 33 Bio2_000494 CCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@H](O)c2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A17 compound treatment 3800.0 1430.0 0.62 4200.0 -243.0 -0.11 0.3563 0.5697 141 Bio2_000495 CCCCC/C=C\CC1OC1C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A18 compound treatment 3880.0 1510.0 0.65 5160.0 717.0 0.33 0.6928 0.9506 34 Bio2_000496 CCCCCCCCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@H](O)c2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A19 compound treatment 3840.0 1470.0 0.63 4640.0 197.0 0.09 0.5116 0.8004 1000003 Bio2_000497 CCCCC/C=C\C[C@@H](O)/C=C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A20 compound treatment 3960.0 1590.0 0.68 4600.0 157.0 0.07 0.5351 0.7776 223 Bio2_000498 CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A21 compound treatment 5120.0 2750.0 1.18 4200.0 -243.0 -0.11 0.7578 0.6376 46 Bio2_000499 CCCCC/C=C\C[C@H](O)/C=C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A22 compound treatment 3400.0 1030.0 0.44 4320.0 -123.0 -0.06 0.2737 0.6123 268 Bio2_000500 CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A23 mock treatment 4040.0 1670.0 0.72 4520.0 77.4 0.04 0.5334 0.7412 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 A24 mock treatment 80.0 -2290.0 -0.98 160.0 -4280.0 -1.97 -2.0885 -0.9487 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B01 mock treatment 120.0 -2250.0 -0.97 5960.0 1520.0 0.7 -0.1905 -0.1598 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B02 mock treatment 200.0 -2170.0 -0.93 4760.0 317.0 0.15 -0.5564 -0.5893 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B03 compound treatment 200.0 -2170.0 -0.93 4920.0 477.0 0.22 -0.5043 -0.5263 1000048 Bio2_000501 CC(C)COCC(CN(Cc1ccccc1)c2ccccc2)N3CCCC3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B04 compound treatment 120.0 -2250.0 -0.97 1680.0 -2760.0 -1.27 -1.5821 -0.9909 2139 Bio2_000502 O[C@H]1C=C2CCN3Cc4cc5OCOc5cc4[C@@H]([C@H]32)[C@@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B05 compound treatment 5920.0 3550.0 1.53 6680.0 2240.0 1.03 1.8074 0.9815 32 Bio2_000503 C/C(=C/1\C(=O)C2C3C(Cc4cccc5[nH]cc3c45)C(C)(C)N2C1=O)/O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B06 compound treatment 280.0 -2090.0 -0.9 520.0 -3920.0 -1.8 -1.9106 -0.9482 3000451 Bio2_000504 CC[C@@]1(O)C(=O)OCc2c1cc3-c4nc5cccc(O)c5cc4Cn3c2=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B07 compound treatment 2480.0 111.0 0.05 4120.0 -323.0 -0.15 -0.0711 -0.4562 3000787 Bio2_000505 [O-][N+](=O)c1ccc(cc1)c2ccc(/C=N/N3CC(=O)NC3=O)o2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B08 compound treatment 920.0 -1450.0 -0.62 1760.0 -2680.0 -1.23 -1.3128 -0.95 2127 Bio2_000506 CC1(C)CCC2=C(O1)c3ccccc3C(=O)C2=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B09 compound treatment 240.0 -2130.0 -0.92 4360.0 -82.6 -0.04 -0.6742 -0.7358 35 Bio2_000507 CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B10 compound treatment 280.0 -2090.0 -0.9 400.0 -4040.0 -1.86 -1.9496 -0.9443 3103826 Bio2_000508 C/C/1=C\CC[C@@]2(C)O[C@@H]2[C@H]3OC(=O)C(=C)[C@@H]3CC1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B11 compound treatment 5080.0 2710.0 1.17 4880.0 437.0 0.2 0.9667 0.817 3103827 Bio2_000509 N/C(=N\C(=O)c1nc(Cl)c(N)nc1N)/NCc2ccc(Cl)cc2Cl 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B12 compound treatment 800.0 -1570.0 -0.67 1080.0 -3360.0 -1.55 -1.5704 -0.9309 1907748 Bio2_000510 CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B13 compound treatment 3640.0 1270.0 0.55 3400.0 -1040.0 -0.48 0.0476 0.0654 3000452 Bio2_000511 *CCN1C(=O)[C@H](OC(=O)C)[C@@H](Sc2ccccc12)c3ccc(OC)cc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B14 compound treatment 80.0 -2290.0 -0.98 120.0 -4320.0 -1.99 -2.1015 -0.9475 3000453 Bio2_000512 C[C@@H]1CC2OC(=O)C(=C)C2[C@H](O)[C@@]3(C)[C@H]1C=CC3=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B15 compound treatment 3960.0 1590.0 0.68 4480.0 37.4 0.02 0.496 0.7247 357 Bio2_000513 Cc1cccc(CCN2CCC(CC2)C(=O)c3ccc(NS(=O)(=O)C)cc3)n1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B16 compound treatment 2960.0 591.0 0.25 4160.0 -283.0 -0.13 0.0879 0.3079 1000105 Bio2_000514 CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B17 compound treatment 2800.0 431.0 0.19 3160.0 -1280.0 -0.59 -0.2859 -0.4625 39 Bio2_000515 Nc1c(S(=O)C(F)(F)F)c(C#N)nn1c2c(Cl)cc(cc2Cl)C(F)(F)F 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B18 compound treatment 4960.0 2590.0 1.11 4000.0 -443.0 -0.2 0.6441 0.5686 1907749 Bio2_000516 CCOC(=O)CN1C(=O)CC(C[C@@H](O)C2C[C@@H](C)C[C@H](C)C2=O)CC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B19 compound treatment 4280.0 1910.0 0.82 4320.0 -123.0 -0.06 0.5413 0.6571 359 Bio2_000517 FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)C(=O)NCC2CCCCN2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B20 compound treatment 2680.0 311.0 0.13 2920.0 -1520.0 -0.7 -0.4004 -0.5618 1907750 Bio2_000518 CC[C@@H]1/C=C(\C)/C[C@H](C)C[C@H](OC)[C@H]2O[C@](O)([C@H](C)C[C@@H]2OC)C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@H](C)[C@@H](O)CC1=O)\C(=C\[C@@H]4CC[C@@H](O)[C@@H](C4)OC)\C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B21 compound treatment 4040.0 1670.0 0.72 4040.0 -403.0 -0.19 0.3773 0.5084 41 Bio2_000519 OC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B22 compound treatment 4400.0 2030.0 0.87 4600.0 157.0 0.07 0.6689 0.7631 2349 Bio2_000520 CC12CC=C3C(CCC4=CC(=O)C=CC43C)C2CC[C@@H]1C(=O)CN5CCN(CC5)c6cc(nc(n6)N7CCCC7)N8CCCC8 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B23 mock treatment 3280.0 911.0 0.39 4040.0 -403.0 -0.19 0.1462 0.3373 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 B24 mock treatment 160.0 -2210.0 -0.95 200.0 -4240.0 -1.95 -2.0511 -0.9453 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C01 mock treatment 5960.0 3590.0 1.54 5440.0 997.0 0.46 1.4164 0.8791 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C02 mock treatment 5040.0 2670.0 1.15 4520.0 77.4 0.04 0.8375 0.7287 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C03 compound treatment 6120.0 3750.0 1.61 4400.0 -42.6 -0.02 1.1269 0.6985 87 Bio2_000521 CCCCC/C=C\C[C@H](OO)/C=C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C04 compound treatment 4280.0 1910.0 0.82 4040.0 -403.0 -0.19 0.4503 0.5345 264 Bio2_000522 CC/C=C\C/C=C\C/C=C\CCCCCCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C05 compound treatment 4160.0 1790.0 0.77 3920.0 -523.0 -0.24 0.3748 0.4645 301 Bio2_000523 COCCCCCCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C06 compound treatment 4200.0 1830.0 0.79 3280.0 -1160.0 -0.53 0.1789 0.1879 233 Bio2_000524 CCCCCCCCCCC/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C07 compound treatment 4440.0 2070.0 0.89 3680.0 -763.0 -0.35 0.3819 0.399 61 Bio2_000525 CCCCC[C@H](O)/C=C/C=C\CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C08 compound treatment 3640.0 1270.0 0.55 4160.0 -283.0 -0.13 0.2947 0.5244 256 Bio2_000526 CCCCC/C=C\C/C=C\CCCCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C09 compound treatment 360.0 -2010.0 -0.86 400.0 -4040.0 -1.86 -1.9253 -0.9393 90 Bio2_000527 CCCCC[C@H](OO)/C=C/C=C\CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C10 compound treatment 4080.0 1710.0 0.74 3600.0 -843.0 -0.39 0.2464 0.2963 221 Bio2_000528 CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C11 compound treatment 5760.0 3390.0 1.46 4000.0 -443.0 -0.2 0.8874 0.6026 304 Bio2_000529 CCCCC[C@H](O)CC[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C12 compound treatment 3400.0 1030.0 0.44 3760.0 -683.0 -0.31 0.0916 0.1687 260 Bio2_000530 CC/C=C\C/C=C\C/C=C\CCCCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C13 compound treatment 2000.0 -369.0 -0.16 3000.0 -1440.0 -0.66 -0.5812 -0.8522 1000009 Bio2_000531 C/C(=C\C=C\C(=C/C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C14 compound treatment 3120.0 751.0 0.32 3600.0 -843.0 -0.39 -0.0455 -0.0903 1000007 Bio2_000532 CCCCCCCCCCCCCCCCOC[C@@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C15 compound treatment 3240.0 871.0 0.37 3320.0 -1120.0 -0.52 -0.1001 -0.1569 149 Bio2_000533 CCCCC(=O)/C=C/C=C\CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C16 compound treatment 3000.0 631.0 0.27 3160.0 -1280.0 -0.59 -0.2251 -0.3467 55 Bio2_000534 CC(=CCC/C(=C/CC/C(=C/CSCC(=O)O)/C)/C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C17 compound treatment 3640.0 1270.0 0.55 2920.0 -1520.0 -0.7 -0.1085 -0.1221 143 Bio2_000535 CCCCCC1OC1C/C=C\C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C18 compound treatment 3520.0 1150.0 0.5 3400.0 -1040.0 -0.48 0.0111 0.0161 217 Bio2_000536 O[C@@H](COc1cccc(c1)C(F)(F)F)/C=C/[C@H]2[C@H](O)C[C@H](O)[C@@H]2C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C19 compound treatment 3360.0 991.0 0.43 3920.0 -523.0 -0.24 0.1315 0.2687 50 Bio2_000537 CCCCC[C@H](O)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C20 compound treatment 5000.0 2630.0 1.13 4080.0 -363.0 -0.17 0.6823 0.5965 231 Bio2_000538 CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C21 compound treatment 4920.0 2550.0 1.1 4000.0 -443.0 -0.2 0.6319 0.5663 89 Bio2_000539 CCCCC[C@H](OO)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C22 compound treatment 3960.0 1590.0 0.68 4280.0 -163.0 -0.07 0.431 0.6261 92 Bio2_000540 CCCCC/C=C\CC1OC1CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C23 mock treatment 4080.0 1710.0 0.74 4840.0 397.0 0.18 0.6496 0.8567 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 C24 mock treatment 120.0 -2250.0 -0.97 160.0 -4280.0 -1.97 -2.0763 -0.9464 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D01 mock treatment 200.0 -2170.0 -0.93 4640.0 197.0 0.09 -0.5954 -0.6353 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D02 mock treatment 80.0 -2290.0 -0.98 3440.0 -1000.0 -0.46 -1.022 -0.9403 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D03 compound treatment 120.0 -2250.0 -0.97 4320.0 -123.0 -0.06 -0.7237 -0.747 43 Bio2_000541 Fc1ccc(cc1)C(N2CCN(C/C=C/c3ccccc3)CC2)c4ccc(F)cc4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D04 compound treatment 160.0 -2210.0 -0.95 3920.0 -523.0 -0.24 -0.8416 -0.8589 1531 Bio2_000542 O=c1n([se]c2ccccc12)c3ccccc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D05 compound treatment 240.0 -2130.0 -0.92 4400.0 -42.6 -0.02 -0.6612 -0.7221 3104253 Bio2_000543 CC(CCCN1CCC2(CC1)N(C)CNC2=O)c3ccc(F)cc3.Fc1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D06 compound treatment 3720.0 1350.0 0.58 3880.0 -563.0 -0.26 0.228 0.3584 1875 Bio2_000544 FC(F)(F)c1ccccc1n2ccnc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D07 compound treatment 4280.0 1910.0 0.82 4440.0 -2.55 0.0 0.5803 0.7061 3000569 Bio2_000545 Cc1cc(C(=O)c2ccccc2Cc3ccccc3)c(C)[nH]1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D08 compound treatment 5160.0 2790.0 1.2 4200.0 -243.0 -0.11 0.7699 0.6387 2372 Bio2_000546 COc1cc(ccc1OC(F)F)c2ccc(=O)[nH]n2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D09 compound treatment 4800.0 2430.0 1.05 3760.0 -683.0 -0.31 0.5174 0.474 70 Bio2_000547 CCCCC[C@H](O)CC(=O)CCc1ccc(O)c(OC)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D10 compound treatment 5040.0 2670.0 1.15 2920.0 -1520.0 -0.7 0.3173 0.2358 3000570 Bio2_000548 CCCNc1ccccc1c2nc3[nH]nnc3c(=O)[nH]2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D11 compound treatment 5360.0 2990.0 1.29 3280.0 -1160.0 -0.53 0.5316 0.3816 72 Bio2_000549 Cc1cnc(cn1)C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D12 compound treatment 2160.0 -209.0 -0.09 3640.0 -803.0 -0.37 -0.3245 -0.8543 3000571 Bio2_000550 *C1=C[C@]2(CC)CCCN3CCc4c(C32)n1c5ccccc45 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D13 compound treatment 3880.0 1510.0 0.65 3200.0 -1240.0 -0.57 0.0555 0.0642 74 Bio2_000551 COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D14 compound treatment 2440.0 71.1 0.03 3360.0 -1080.0 -0.5 -0.3304 -0.6624 2337 Bio2_000552 COc1cc2CCn3c(cc(=Nc4c(C)cc(C)cc4C)n(C)c3=O)-c2cc1OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D15 compound treatment 3040.0 671.0 0.29 3840.0 -603.0 -0.28 0.0082 0.0204 76 Bio2_000553 CC1(C)[C@@H](O)C[C@@H]2[C@]1(O)[C@H](O)C[C@@]3(C[C@@](C)(O)C4CC[C@H]3[C@@]2(C)O)[C@@H]4O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D16 compound treatment 2600.0 231.0 0.1 3920.0 -523.0 -0.24 -0.0996 -0.3831 1907751 Bio2_000554 CN/C(=N\c1ccc(cc1)C2=NNC(=O)CC2C)/NC#N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D17 compound treatment 3080.0 711.0 0.31 4240.0 -203.0 -0.09 0.1504 0.4704 78 Bio2_000555 C[C@]1(Cc2cc(OCC(=O)O)c(Cl)c(Cl)c2C1=O)C3CCCC3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D18 compound treatment 3360.0 991.0 0.43 4040.0 -403.0 -0.19 0.1705 0.3669 1000092 Bio2_000556 COc1ccc(cc1OC2CCCC2)C3CNC(=O)C3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D19 compound treatment 2800.0 431.0 0.19 3920.0 -523.0 -0.24 -0.0388 -0.1278 3103683 Bio2_000557 COc1ccccc1.CS[C@H](C)[C@H](OC(=O)C)C(=O)N(C)CCN(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D20 compound treatment 3720.0 1350.0 0.58 4800.0 357.0 0.16 0.5271 0.8729 2270 Bio2_000558 CCCCOc1cc(CC2CNC(=O)N2)ccc1OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D21 compound treatment 3440.0 1070.0 0.46 3920.0 -523.0 -0.24 0.1558 0.2999 362 Bio2_000559 CCN(CC)CC(=O)Nc1c(C)cccc1C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D22 compound treatment 4000.0 1630.0 0.7 5160.0 717.0 0.33 0.7293 0.9408 1865 Bio2_000560 Clc1cccc(Nc2nnc(c3ccccc3)c4ccccc24)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D23 mock treatment 3640.0 1270.0 0.55 4440.0 -2.55 0.0 0.3857 0.7056 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 D24 mock treatment 160.0 -2210.0 -0.95 240.0 -4200.0 -1.93 -2.0381 -0.9465 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E01 mock treatment 6040.0 3670.0 1.58 4880.0 437.0 0.2 1.2586 0.7908 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E02 mock treatment 4840.0 2470.0 1.06 3160.0 -1280.0 -0.59 0.3345 0.2752 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E03 compound treatment 5280.0 2910.0 1.25 4120.0 -323.0 -0.15 0.7804 0.619 308 Bio2_000561 CCCCC/C=C/C=C/1\[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E04 compound treatment 4320.0 1950.0 0.84 3920.0 -523.0 -0.24 0.4234 0.4851 94 Bio2_000562 CCCCCC1OC1C/C=C\CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E05 compound treatment 4560.0 2190.0 0.94 3640.0 -803.0 -0.37 0.4054 0.4006 147 Bio2_000563 CCCCCC(=O)/C=C/C=C\C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E06 compound treatment 3320.0 951.0 0.41 3920.0 -523.0 -0.24 0.1193 0.2516 1000018 Bio2_000564 CCCCC/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E07 compound treatment 4400.0 2030.0 0.87 4400.0 -42.6 -0.02 0.6038 0.6911 259 Bio2_000565 CCCCC(C)(C)[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E08 compound treatment 3680.0 1310.0 0.56 3040.0 -1400.0 -0.64 -0.0573 -0.0669 3000590 Bio2_000566 **(*)S[C@H](/C=C/C=C/C=C\C/C=C\CCCCC)[C@@H](O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E09 compound treatment 4520.0 2150.0 0.93 3480.0 -963.0 -0.44 0.3412 0.3327 272 Bio2_000567 OC(=O)CCCCCCCCCCCCCCCC#C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E10 compound treatment 4080.0 1710.0 0.74 2920.0 -1520.0 -0.7 0.0253 0.0249 3000609 Bio2_000568 *C(=O)[C@H](CS)NS[C@H](/C=C/C=C/C=C\C/C=C\CCCCC)[C@@H](O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E11 compound treatment 4240.0 1870.0 0.8 3720.0 -723.0 -0.33 0.3341 0.3837 300 Bio2_000569 O[C@@H](CCc1ccccc1)/C=C/[C@H]2[C@H](O)CC(=O)[C@@H]2C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E12 compound treatment 2400.0 31.1 0.01 3360.0 -1080.0 -0.5 -0.3425 -0.6879 3000610 Bio2_000570 *[C@H](/C=C/C=C/C=C\C/C=C\CCCCC)[C@@H](O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E13 compound treatment 2800.0 431.0 0.19 3080.0 -1360.0 -0.63 -0.3119 -0.4774 109 Bio2_000571 CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E14 compound treatment 3040.0 671.0 0.29 2920.0 -1520.0 -0.7 -0.291 -0.3842 22 Bio2_000572 CCCCC/C=C\C/C=C\CCCCCCCC(=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E15 compound treatment 3320.0 951.0 0.41 4160.0 -283.0 -0.13 0.1974 0.4599 179 Bio2_000573 CCCCCCCCCCCCCCCCOC[C@H](CO)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E16 compound treatment 2920.0 551.0 0.24 2800.0 -1640.0 -0.76 -0.3665 -0.4629 270 Bio2_000574 CCCCC/C=C\C/C=C\CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E17 compound treatment 3640.0 1270.0 0.55 3400.0 -1040.0 -0.48 0.0476 0.0654 81 Bio2_000575 CCCCCCCCCCCCCCCCOCC(COP(=O)(O)OCC[N+](C)(C)C)OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E18 compound treatment 3080.0 711.0 0.31 3160.0 -1280.0 -0.59 -0.2008 -0.3022 229 Bio2_000576 CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E19 compound treatment 3240.0 871.0 0.37 3080.0 -1360.0 -0.63 -0.1781 -0.244 183 Bio2_000577 CCCCCCCCCCCCCCCCOCC(CO)OC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E20 compound treatment 3040.0 671.0 0.29 3320.0 -1120.0 -0.52 -0.1609 -0.2721 186 Bio2_000578 CCCCC[C@H](O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E21 compound treatment 3200.0 831.0 0.36 3680.0 -763.0 -0.35 0.0048 0.0096 181 Bio2_000579 CCCCCCCCCCCCCCCCOCC(CO)OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E22 compound treatment 3520.0 1150.0 0.5 4280.0 -163.0 -0.07 0.2972 0.5936 3000631 Bio2_000580 *P(=O)OC[C@H](NC(=O)CCCCCCCCCCCCCCC)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E23 mock treatment 3920.0 1550.0 0.67 4240.0 -203.0 -0.09 0.4058 0.6025 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 E24 mock treatment 120.0 -2250.0 -0.97 160.0 -4280.0 -1.97 -2.0763 -0.9464 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F01 mock treatment 320.0 -2050.0 -0.88 4040.0 -403.0 -0.19 -0.754 -0.8374 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F02 mock treatment 320.0 -2050.0 -0.88 3760.0 -683.0 -0.31 -0.845 -0.9034 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F03 compound treatment 400.0 -1970.0 -0.85 4280.0 -163.0 -0.07 -0.6516 -0.7665 80 Bio2_000581 CN(C)C(=O)C(CCN1CCC(O)(CC1)c2ccc(Cl)cc2)(c3ccccc3)c4ccccc4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F04 compound treatment 240.0 -2130.0 -0.92 3560.0 -883.0 -0.41 -0.9344 -0.933 3000632 Bio2_000582 *CCNS(=O)(=O)c1cccc2c(Cl)cccc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F05 compound treatment 2280.0 -88.9 -0.04 3160.0 -1280.0 -0.59 -0.444 -0.7514 372 Bio2_000583 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2cc(OC)c(OC)c(OC)c2)cc1OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F06 compound treatment 5200.0 2830.0 1.22 3480.0 -963.0 -0.44 0.548 0.423 47 Bio2_000584 CC(=CCC/C(=C/CC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)/C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F07 compound treatment 5240.0 2870.0 1.23 4400.0 -42.6 -0.02 0.8593 0.6958 82 Bio2_000585 Nc1cc(nc(N)[n+]1[O-])N2CCCCC2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F08 compound treatment 280.0 -2090.0 -0.9 160.0 -4280.0 -1.97 -2.0277 -0.9368 3000633 Bio2_000586 Cc1ccc(C(=O)*2****o2)c3nc4c(C(=O)*5****o5)c(N)c(=O)c(C)c4oc13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F09 compound treatment 5680.0 3310.0 1.42 3840.0 -603.0 -0.28 0.811 0.559 84 Bio2_000587 Nc1cc(nc(N)[n+]1OS(=O)(=O)O)N2CCCCC2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F10 compound treatment 5280.0 2910.0 1.25 2840.0 -1600.0 -0.74 0.3642 0.2507 1907752 Bio2_000588 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCc1ccc(O)c(OC)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F11 compound treatment 4000.0 1630.0 0.7 2880.0 -1560.0 -0.72 -0.012 -0.012 86 Bio2_000589 COC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCCN(C)Cc3ccccc3)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F12 compound treatment 2680.0 311.0 0.13 2760.0 -1680.0 -0.77 -0.4525 -0.5763 331 Bio2_000590 COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F13 compound treatment 2080.0 -289.0 -0.12 3200.0 -1240.0 -0.57 -0.4919 -0.8412 110 Bio2_000591 COC(=O)C1=C(C)NC(=C(C1c2ccccc2[N+](=O)[O-])C(=O)OC)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F14 compound treatment 3400.0 1030.0 0.44 2640.0 -1800.0 -0.83 -0.2725 -0.2899 333 Bio2_000592 NC(=S)/C(=C/c1ccc(O)c(O)c1)/C#N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F15 compound treatment 3520.0 1150.0 0.5 3840.0 -603.0 -0.28 0.1541 0.2717 112 Bio2_000593 OC(=O)c1cccnc1Nc2cccc(c2)C(F)(F)F 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F16 compound treatment 2880.0 511.0 0.22 3600.0 -843.0 -0.39 -0.1185 -0.2661 203 Bio2_000594 NC(=C(C#N)C#N)/C(=C/c1ccc2[nH]ccc2c1)/C#N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F17 compound treatment 3120.0 751.0 0.32 3320.0 -1120.0 -0.52 -0.1366 -0.2243 907431 Bio2_000595 COC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCCCN3CCC(CC3)(c4ccccc4)c5ccccc5)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F18 compound treatment 3280.0 911.0 0.39 2720.0 -1720.0 -0.79 -0.283 -0.3202 3 Bio2_000596 Oc1ccc(/C=C(\C#N)/C(=O)NCc2ccccc2)cc1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F19 compound treatment 2200.0 -169.0 -0.07 2480.0 -1960.0 -0.9 -0.6895 -0.7616 115 Bio2_000597 COCCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC(C)C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F20 compound treatment 240.0 -2130.0 -0.92 320.0 -4120.0 -1.9 -1.9878 -0.9443 208 Bio2_000598 CC(C)(C)c1cc(/C=C(\C#N)/C(=S)N)cc(c1O)C(C)(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F21 compound treatment 3280.0 911.0 0.39 3680.0 -763.0 -0.35 0.0291 0.0554 117 Bio2_000599 CCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OC)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F22 compound treatment 3920.0 1550.0 0.67 4080.0 -363.0 -0.17 0.3538 0.5146 2413 Bio2_000600 CC(C)CC(NC(=O)CNC(=O)C(C)(C)NC(=O)C(NC(=O)C(C)(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C1CCCN1C(=O)C(C)(C)NC(=O)C)C(C)C)C(=O)NC(C)(C)C(=O)N2CCCC2C(=O)NC(C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CO)Cc3ccccc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F23 mock treatment 3800.0 1430.0 0.62 4400.0 -42.6 -0.02 0.4214 0.6843 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 F24 mock treatment 120.0 -2250.0 -0.97 200.0 -4240.0 -1.95 -2.0633 -0.9476 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G01 mock treatment 4880.0 2510.0 1.08 5040.0 597.0 0.27 0.9579 0.8596 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G02 mock treatment 5080.0 2710.0 1.17 4160.0 -283.0 -0.13 0.7326 0.6245 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G03 compound treatment 4800.0 2430.0 1.05 3480.0 -963.0 -0.44 0.4264 0.3755 83 Bio2_000601 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G04 compound treatment 4680.0 2310.0 0.99 3640.0 -803.0 -0.37 0.4419 0.4168 191 Bio2_000602 CCCc1c(O)c(ccc1OCCCCc2nnn[nH]2)C(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G05 compound treatment 3920.0 1550.0 0.67 3520.0 -923.0 -0.42 0.1717 0.2172 173 Bio2_000603 CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](CO)OC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G06 compound treatment 3680.0 1310.0 0.56 3600.0 -843.0 -0.39 0.1248 0.1824 3000641 Bio2_000604 *CCOP(=O)(O)OC[C@H](O)COCCCCCCCCCCCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G07 compound treatment 4600.0 2230.0 0.96 3320.0 -1120.0 -0.52 0.3135 0.2877 177 Bio2_000605 CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC/C=C\C/C=C\CCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G08 compound treatment 4480.0 2110.0 0.91 3280.0 -1160.0 -0.53 0.264 0.2506 111 Bio2_000606 CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G09 compound treatment 4160.0 1790.0 0.77 2960.0 -1480.0 -0.68 0.0627 0.0609 175 Bio2_000607 CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G10 compound treatment 4600.0 2230.0 0.96 3160.0 -1280.0 -0.59 0.2615 0.2322 36 Bio2_000608 CCCCCCCCCCCCCC(=O)N[C@H](C)[C@@H](O)c1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G11 compound treatment 3880.0 1510.0 0.65 2960.0 -1480.0 -0.68 -0.0225 -0.0239 102 Bio2_000609 C[C@H](CC[C@@H](O)C(C)(C)O)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)CCC3=C)/CCC[C@]12C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G12 compound treatment 3080.0 711.0 0.31 3120.0 -1320.0 -0.61 -0.2138 -0.314 1000002 Bio2_000610 CCCCCCCCCCCCCC(=O)N[C@@H](C)[C@H](O)c1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G13 compound treatment 2920.0 551.0 0.24 2960.0 -1480.0 -0.68 -0.3144 -0.4357 98 Bio2_000611 C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2/C(=C/C=C\3/C[C@@H](O)CCC3=C)/CCC[C@]12C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G14 compound treatment 2560.0 191.0 0.08 3040.0 -1400.0 -0.64 -0.3979 -0.612 227 Bio2_000612 CCCCCCCC/C=C\C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G15 compound treatment 2840.0 471.0 0.2 2320.0 -2120.0 -0.98 -0.5469 -0.5486 118 Bio2_000613 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OC(CO)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G16 compound treatment 2760.0 391.0 0.17 3600.0 -843.0 -0.39 -0.155 -0.367 8 Bio2_000614 CCCCCCCC/C=C\C/C=C\C/C=C\CCCC(=O)NCCO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G17 compound treatment 3120.0 751.0 0.32 2560.0 -1880.0 -0.87 -0.3837 -0.4153 276 Bio2_000615 CCCCCCCCCCCCCCC(F)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G18 compound treatment 3040.0 671.0 0.29 2800.0 -1640.0 -0.76 -0.33 -0.4081 136 Bio2_000616 COC(C)(C)CCCC(C)C/C=C/C(=C/C(=O)O)/C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G19 compound treatment 3560.0 1190.0 0.51 2880.0 -1560.0 -0.72 -0.1458 -0.1653 274 Bio2_000617 CCCCCCCCCCCCC(O)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G20 compound treatment 3400.0 1030.0 0.44 3760.0 -683.0 -0.31 0.0916 0.1687 310 Bio2_000618 CCCCC(C)(O)C/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G21 compound treatment 3080.0 711.0 0.31 3440.0 -1000.0 -0.46 -0.1097 -0.1983 130 Bio2_000619 C/C(=C\C=C\C(=C\C(=O)Nc1ccc(O)cc1)\C)/C=C/C2=C(C)CCCC2(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G22 compound treatment 4000.0 1630.0 0.7 3080.0 -1360.0 -0.63 0.053 0.0564 309 Bio2_000620 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)N(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G23 mock treatment 3120.0 751.0 0.32 4040.0 -403.0 -0.19 0.0975 0.262 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 G24 mock treatment 120.0 -2250.0 -0.97 280.0 -4160.0 -1.91 -2.0373 -0.95 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H01 mock treatment 200.0 -2170.0 -0.93 4320.0 -123.0 -0.06 -0.6994 -0.7485 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H02 mock treatment 240.0 -2130.0 -0.92 4000.0 -443.0 -0.2 -0.7913 -0.8437 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H03 compound treatment 240.0 -2130.0 -0.92 3720.0 -723.0 -0.33 -0.8823 -0.9059 119 Bio2_000621 OC(=O)c1ccccc1Nc2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H04 compound treatment 1080.0 -1290.0 -0.55 2920.0 -1520.0 -0.7 -0.887 -0.9933 556 Bio2_000622 COc1cc2ncc(nc2cc1OC)c3ccccc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H05 compound treatment 5080.0 2710.0 1.17 3480.0 -963.0 -0.44 0.5115 0.4101 3001877 Bio2_000623 OC(=O)c1cc(O)ccc1NCCCc2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H06 compound treatment 6200.0 3830.0 1.65 3440.0 -1000.0 -0.46 0.8391 0.4904 3001878 Bio2_000624 Cc1[nH]c(=O)c([N+]#[C-])cc1c2ccncc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H07 compound treatment 5480.0 3110.0 1.34 3160.0 -1280.0 -0.59 0.5291 0.3619 2450 Bio2_000625 Oc1ccc(cc1n2c(=O)[nH]c3cc(ccc23)C(F)(F)F)C(F)(F)F 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H08 compound treatment 5040.0 2670.0 1.15 3000.0 -1440.0 -0.66 0.3433 0.2588 2080829 Bio2_000626 OCC1(CO)N2CCC(CC2)C1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H09 compound treatment 5880.0 3510.0 1.51 3040.0 -1400.0 -0.64 0.6117 0.3726 124 Bio2_000627 CC(C)(O)[C@H]1O[C@H]2CC[C@]3(C)[C@]4(C)[C@H](Cc5c4[nH]c6ccccc56)CC[C@@]3(O)C2=CC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H10 compound treatment 3160.0 791.0 0.34 2120.0 -2320.0 -1.07 -0.5146 -0.4591 1907753 Bio2_000628 CC[C@@H]1[C@H](C)C[C@@H]2[C@H]3C[C@H]4CCC(=O)C5=C(O)[C@H](CCCNC(=O)/C=C\C[C@@H]4[C@H]3C=C[C@@H]12)NC5=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H11 compound treatment 4040.0 1670.0 0.72 3360.0 -1080.0 -0.5 0.1562 0.1787 126 Bio2_000629 CC1(C)Oc2ccc(C#N)cc2[C@@H](OC3=CC(=O)CC3)[C@@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H12 compound treatment 2800.0 431.0 0.19 2720.0 -1720.0 -0.79 -0.429 -0.5273 354 Bio2_000630 Nc1ccc2C(=O)NC(=O)c3cccc1c32 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H13 compound treatment 3080.0 711.0 0.31 2920.0 -1520.0 -0.7 -0.2788 -0.3649 128 Bio2_000631 CC(=C)[C@H]1O[C@H]2CC[C@]3(C)[C@]4(C)[C@@H](CC[C@@]3(O)[C@@]52O[C@@H]5[C@H]1O)[C@@H]6OC(C)(C)[C@H]7C[C@@H]8C(=C)Cc9c(Cl)cc%10[nH]c4c6c%10c9[C@@]87O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H14 compound treatment 2760.0 391.0 0.17 2640.0 -1800.0 -0.83 -0.4671 -0.5523 445 Bio2_000632 NC(=O)c1cccc(N)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H15 compound treatment 3240.0 871.0 0.37 2400.0 -2040.0 -0.94 -0.3992 -0.3948 2474 Bio2_000633 Nc1nc(N)c(nc1Cl)C(=O)NC(=N)Nc2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H16 compound treatment 2280.0 -88.9 -0.04 2320.0 -2120.0 -0.98 -0.7172 -0.7342 1907754 Bio2_000634 CO[C@H]1C[C@H](C)CC2=C(NCC=C)C(=O)C=C(NC(=O)/C(=C/C=C\[C@H](OC)[C@@H](OC(=O)N)/C(=C/[C@H](C)[C@H]1O)/C)/C)C2=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H17 compound treatment 3280.0 911.0 0.39 2640.0 -1800.0 -0.83 -0.309 -0.337 153 Bio2_000635 CC1=CC=C(CC1)N(CC2=NCCN2)c3cccc(O)c3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H18 compound treatment 120.0 -2250.0 -0.97 160.0 -4280.0 -1.97 -2.0763 -0.9464 3001880 Bio2_000636 CC(=O)O[C@@H]1[C@@H](O)CN[C@@H]1Cc2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H19 compound treatment 2760.0 391.0 0.17 3160.0 -1280.0 -0.59 -0.2981 -0.486 3001155 Bio2_000637 CC1(C)NC(=O)NC1=O.c1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H20 compound treatment 2480.0 111.0 0.05 2720.0 -1720.0 -0.79 -0.5263 -0.6632 154 Bio2_000638 C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H]1CC[C@H]3C[C@@H]4C[C@@]32CC[C@]4(O)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H21 compound treatment 2200.0 -169.0 -0.07 1960.0 -2480.0 -1.14 -0.8585 -0.7506 156 Bio2_000639 Fc1ccc(cc1)C(CCCN2CCC(CC2)n3c(=O)[nH]c4ccccc34)c5ccc(F)cc5Cl 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H22 compound treatment 3520.0 1150.0 0.5 2800.0 -1640.0 -0.76 -0.184 -0.2037 401 Bio2_000640 COc1cccc2c1cc([N+](=O)[O-])c3c(cc4OCOc4c23)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H23 mock treatment 3600.0 1230.0 0.53 3240.0 -1200.0 -0.55 -0.0166 -0.0217 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 H24 mock treatment 160.0 -2210.0 -0.95 200.0 -4240.0 -1.95 -2.0511 -0.9453 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I01 mock treatment 4640.0 2270.0 0.98 4920.0 477.0 0.22 0.8459 0.845 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I02 mock treatment 4480.0 2110.0 0.91 3920.0 -523.0 -0.24 0.4721 0.5027 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I03 compound treatment 4680.0 2310.0 0.99 3640.0 -803.0 -0.37 0.4419 0.4168 299 Bio2_000641 CCCCCCCCCCOCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I04 compound treatment 4600.0 2230.0 0.96 3080.0 -1360.0 -0.63 0.2355 0.2055 184 Bio2_000642 CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SCC(NC(=O)C)C(=O)O)[C@@H](O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I05 compound treatment 4480.0 2110.0 0.91 2720.0 -1720.0 -0.79 0.0819 0.068 13 Bio2_000643 CCCCC/C=C\C/C=C\C/C=C\C=C\[C@@H](O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I06 compound treatment 4840.0 2470.0 1.06 3200.0 -1240.0 -0.57 0.3475 0.288 14 Bio2_000644 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I07 compound treatment 3960.0 1590.0 0.68 3520.0 -923.0 -0.42 0.1839 0.2284 64 Bio2_000645 CCCCC/C=C\C/C=C\C/C=C\C=C\[C@H](CCCC(=O)O)OO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I08 compound treatment 4440.0 2070.0 0.89 2640.0 -1800.0 -0.83 0.0438 0.036 123 Bio2_000646 CCCCC/C=C\C/C=C\CCCCCCCC(=O)NCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I09 compound treatment 4560.0 2190.0 0.94 2880.0 -1560.0 -0.72 0.1583 0.1336 137 Bio2_000647 CCCCC/C=C\C/C=C\C/C=C\CC1OC1CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I10 compound treatment 4240.0 1870.0 0.8 3040.0 -1400.0 -0.64 0.113 0.1096 40 Bio2_000648 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I11 compound treatment 4400.0 2030.0 0.87 2880.0 -1560.0 -0.72 0.1096 0.0969 146 Bio2_000649 CCCCCC#CCC#CCC#CCC#CCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I12 compound treatment 2800.0 431.0 0.19 2800.0 -1640.0 -0.76 -0.403 -0.5181 66 Bio2_000650 CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I13 compound treatment 2920.0 551.0 0.24 2400.0 -2040.0 -0.94 -0.4965 -0.5126 144 Bio2_000651 CCCCCCCCC#CCC#CCC#CCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I14 compound treatment 3120.0 751.0 0.32 2600.0 -1840.0 -0.85 -0.3707 -0.4088 69 Bio2_000652 CCCCCCCC/C=C\CCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I15 compound treatment 2640.0 271.0 0.12 2960.0 -1480.0 -0.68 -0.3996 -0.5778 145 Bio2_000653 CCCCC/C=C\C/C=C\C/C=C\C=C\C(=O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I16 compound treatment 2480.0 111.0 0.05 2720.0 -1720.0 -0.79 -0.5263 -0.6632 318 Bio2_000654 CCCCCCCCCCCCCCCC(=O)NCCO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I17 compound treatment 2640.0 271.0 0.12 2920.0 -1520.0 -0.7 -0.4126 -0.5813 120 Bio2_000655 O=Cc1c2[nH]c3ccccc3c2cc4[nH]c5ccccc5c14 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I18 compound treatment 2840.0 471.0 0.2 3080.0 -1360.0 -0.63 -0.2997 -0.4552 114 Bio2_000656 CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)O)OC(=O)CCCCCCCCCCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I19 compound treatment 2640.0 271.0 0.12 2520.0 -1920.0 -0.88 -0.5426 -0.6086 257 Bio2_000657 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC(=O)CCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I20 compound treatment 3960.0 1590.0 0.68 3640.0 -803.0 -0.37 0.2229 0.2867 190 Bio2_000658 CCCCC[C@H](O)/C=C/[C@H]1C=CC(=O)[C@@H]1CCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I21 compound treatment 2920.0 551.0 0.24 2880.0 -1560.0 -0.72 -0.3404 -0.45 258 Bio2_000659 CCCCCCCCCCC/C=C\C(C)(C)/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I22 compound treatment 3800.0 1430.0 0.62 3760.0 -683.0 -0.31 0.2133 0.3087 212 Bio2_000660 CCCCC[C@H](O)/C=C/[C@H]1C=CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I23 mock treatment 4000.0 1630.0 0.7 4160.0 -283.0 -0.13 0.4042 0.5665 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 I24 mock treatment 120.0 -2250.0 -0.97 160.0 -4280.0 -1.97 -2.0763 -0.9464 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J01 mock treatment 280.0 -2090.0 -0.9 3960.0 -483.0 -0.22 -0.7921 -0.856 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J02 mock treatment 200.0 -2170.0 -0.93 4280.0 -163.0 -0.07 -0.7124 -0.7613 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J03 compound treatment 4600.0 2230.0 0.96 3600.0 -843.0 -0.39 0.4045 0.3909 3104408 Bio2_000661 CC(N/C(=N\C#N)/Nc1ccncc1)C(C)(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J04 compound treatment 7280.0 4910.0 2.11 3320.0 -1120.0 -0.52 1.1285 0.519 1907755 Bio2_000662 COCc1nc2n(CC(C)C)c(=O)n(C)c(=O)c2[nH]1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J05 compound treatment 1840.0 -529.0 -0.23 3760.0 -683.0 -0.31 -0.3828 -0.9875 2431 Bio2_000663 CCN(CC)CCNC(=O)c1ccc(N)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J06 compound treatment 1000.0 -1370.0 -0.59 560.0 -3880.0 -1.79 -1.6786 -0.893 1907756 Bio2_000664 Clc1ccc2ncnc(NCc3ccc4OCOc4c3)c2c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J07 compound treatment 4640.0 2270.0 0.98 4120.0 -323.0 -0.15 0.5858 0.5929 3104409 Bio2_000665 CCCNCC(O)COc1ccccc1.CC(=O)CCc1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J08 compound treatment 3560.0 1190.0 0.51 2680.0 -1760.0 -0.81 -0.2108 -0.2199 155 Bio2_000666 CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC[C@@H](NC[C@@H](N)CS)C(C)C)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J09 compound treatment 3840.0 1470.0 0.63 3080.0 -1360.0 -0.63 0.0044 0.0049 161 Bio2_000667 COc1ccc2nccc(C(O)[C@H]3CC4CC[C@@H]3CC4C=C)c2c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J10 compound treatment 3520.0 1150.0 0.5 3640.0 -803.0 -0.37 0.0891 0.1443 361 Bio2_000668 CC(C)(c1ccc(OCC2CO2)cc1)c3ccc(OCC4CO4)cc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J11 compound treatment 3840.0 1470.0 0.63 2680.0 -1760.0 -0.81 -0.1257 -0.1223 1000050 Bio2_000669 COc1ccc2nccc([C@@H](O)[C@@H]3CC4CC[C@@H]3CC4C=C)c2c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J12 compound treatment 3120.0 751.0 0.32 2880.0 -1560.0 -0.72 -0.2796 -0.355 3103962 Bio2_000670 CO[C@H]1/C=C/C=C(\C)/C[C@@H](C)[C@H](O)[C@H](C)/C=C(\C)/C=C(\OC)/C(=O)O[C@@H]1[C@@H](C)[C@@H](O)[C@H](C)[C@H]2C[C@@H](O)[C@H](C)[C@H](O2)C(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J13 compound treatment 2920.0 551.0 0.24 2800.0 -1640.0 -0.76 -0.3665 -0.4629 907369 Bio2_000671 CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J14 compound treatment 1600.0 -769.0 -0.33 1520.0 -2920.0 -1.34 -1.1841 -0.8556 3103963 Bio2_000672 CC(=O)OCOC(=O)CNc1ccccc1OCCOc2ccccc2NCC(=O)OCOC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J15 compound treatment 2680.0 311.0 0.13 2680.0 -1760.0 -0.81 -0.4785 -0.5825 3103964 Bio2_000673 CC(C)[C@]1(O)[C@@H](OC(=O)c2ccc[nH]2)[C@]3(O)[C@]4(O)[C@]1(C)[C@]5(O)C[C@@]3(C)[C@@]6(O)CC[C@H](C)[C@@H](O)[C@]46O5 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J16 compound treatment 2800.0 431.0 0.19 2960.0 -1480.0 -0.68 -0.3509 -0.4967 3103618 Bio2_000674 Cc1ccc2N=C3N(CCC3(O)C(=O)c2c1)c4ccccc4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J17 compound treatment 3200.0 831.0 0.36 3360.0 -1080.0 -0.5 -0.0992 -0.1619 165 Bio2_000675 OC(COc1cccc2[nH]c(C#N)cc12)CN3CCN(CC3)C(c4ccccc4)c5ccccc5 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J18 compound treatment 2680.0 311.0 0.13 3080.0 -1360.0 -0.63 -0.3484 -0.5438 3001881 Bio2_000676 */C=C(/CC(=O)O)\C=C\[C@@H](C)C\C=C\CC/C=C/C=C\CC/C(=C\C=C(\*)/C)/C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J19 compound treatment 2760.0 391.0 0.17 2280.0 -2160.0 -0.99 -0.5842 -0.5793 390 Bio2_000677 COc1ccc(CCCOC(Cn2ccnc2)c3ccc(OC)cc3)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J20 compound treatment 3720.0 1350.0 0.58 3400.0 -1040.0 -0.48 0.0719 0.0955 1000439 Bio2_000678 CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NCc4ccc(I)cc4)ncnc23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J21 compound treatment 2520.0 151.0 0.06 2680.0 -1760.0 -0.81 -0.5271 -0.6483 193 Bio2_000679 COc1cc2CCN(C)[C@H]3Cc4ccc(OC)c(Oc5ccc(C[C@@H]6N(C)CCc7cc(OC)c(Oc(c1OC)c32)cc67)cc5)c4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J22 compound treatment 3240.0 871.0 0.37 3120.0 -1320.0 -0.61 -0.1651 -0.2311 3104702 Bio2_000680 C[C@H]1CCC/C=C/C2C[C@H](O)C[C@H]2[C@H](O)/C=C/C(=O)O1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J23 mock treatment 2960.0 591.0 0.25 3800.0 -643.0 -0.3 -0.0292 -0.0748 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 J24 mock treatment 200.0 -2170.0 -0.93 240.0 -4200.0 -1.93 -2.026 -0.9442 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K01 mock treatment 4040.0 1670.0 0.72 4760.0 317.0 0.15 0.6114 0.8337 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K02 mock treatment 5760.0 3390.0 1.46 4880.0 437.0 0.2 1.1735 0.7971 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K03 compound treatment 5400.0 3030.0 1.3 4480.0 37.4 0.02 0.934 0.7164 139 Bio2_000681 CCCCC/C=C\C/C=C\CC1OC1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K04 compound treatment 4240.0 1870.0 0.8 4120.0 -323.0 -0.15 0.4641 0.5672 214 Bio2_000682 CCCCC[C@H](O)/C=C/C1=C(CCCCCCC(=O)O)C(=O)CC1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K05 compound treatment 5360.0 2990.0 1.29 3120.0 -1320.0 -0.61 0.4796 0.3371 1000033 Bio2_000683 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@H]1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K06 compound treatment 3400.0 1030.0 0.44 3600.0 -843.0 -0.39 0.0396 0.0673 216 Bio2_000684 CCCCC[C@H](O)/C=C/C1=C(C/C=C\CCCC(=O)O)C(=O)CC1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K07 compound treatment 4000.0 1630.0 0.7 3400.0 -1040.0 -0.48 0.1571 0.1848 57 Bio2_000685 CCCCC/C=C\C=C\[C@@H](O)CCCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K08 compound treatment 4360.0 1990.0 0.86 3120.0 -1320.0 -0.61 0.1755 0.1671 218 Bio2_000686 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@@H](O)CC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K09 compound treatment 4080.0 1710.0 0.74 3080.0 -1360.0 -0.63 0.0773 0.08 88 Bio2_000687 CCCCC/C=C\C=C\[C@H](CCCCCCCC(=O)O)OO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K10 compound treatment 5320.0 2950.0 1.27 3200.0 -1240.0 -0.57 0.4934 0.3545 220 Bio2_000688 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K11 compound treatment 4760.0 2390.0 1.03 2680.0 -1760.0 -0.81 0.1541 0.1177 45 Bio2_000689 CCCCCCCC/C=C\CCCCCCCC(=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K12 compound treatment 3920.0 1550.0 0.67 3080.0 -1360.0 -0.63 0.0287 0.0313 222 Bio2_000690 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K13 compound treatment 2280.0 -88.9 -0.04 2720.0 -1720.0 -0.79 -0.5871 -0.7404 1000028 Bio2_000691 CCCCC[C@H](O)/C=C/[C@H]1[C@@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K14 compound treatment 2920.0 551.0 0.24 2800.0 -1640.0 -0.76 -0.3665 -0.4629 226 Bio2_000692 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K15 compound treatment 3320.0 951.0 0.41 2880.0 -1560.0 -0.72 -0.2188 -0.2647 1000027 Bio2_000693 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H](O)[C@@H]1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K16 compound treatment 2720.0 351.0 0.15 2960.0 -1480.0 -0.68 -0.3753 -0.5374 224 Bio2_000694 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@H](O)[C@@H]1C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K17 compound treatment 1560.0 -809.0 -0.35 1800.0 -2640.0 -1.22 -1.1052 -0.8744 1000008 Bio2_000695 C/C(=C/C=C/C(=C/C(=O)O)/C)/C=C/C1=C(C)CCCC1(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K18 compound treatment 2560.0 191.0 0.08 2480.0 -1960.0 -0.9 -0.58 -0.6401 3184 Bio2_000696 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H]2O/C(=C\CCCC(=O)O)/C[C@H]12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K19 compound treatment 2960.0 591.0 0.25 2960.0 -1480.0 -0.68 -0.3023 -0.4155 47 Bio2_000697 CC(=CCC/C(=C/CC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)/C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K20 compound treatment 3120.0 751.0 0.32 3480.0 -963.0 -0.44 -0.0845 -0.1543 267 Bio2_000698 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)C=CC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K21 compound treatment 2720.0 351.0 0.15 3080.0 -1360.0 -0.63 -0.3362 -0.5217 266 Bio2_000699 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K22 compound treatment 2080.0 -289.0 -0.12 2320.0 -2120.0 -0.98 -0.778 -0.7907 104 Bio2_000700 C/C(=C\C=C\C(=C\C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K23 mock treatment 3000.0 631.0 0.27 3200.0 -1240.0 -0.57 -0.2121 -0.3353 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 K24 mock treatment 80.0 -2290.0 -0.98 160.0 -4280.0 -1.97 -2.0885 -0.9487 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L01 mock treatment 200.0 -2170.0 -0.93 4280.0 -163.0 -0.07 -0.7124 -0.7613 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L02 mock treatment 160.0 -2210.0 -0.95 5400.0 957.0 0.44 -0.3604 -0.3442 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L03 compound treatment 160.0 -2210.0 -0.95 4480.0 37.4 0.02 -0.6596 -0.6942 194 Bio2_000701 CCCCCCCC(=O)O[C@@H]1[C@@H](OC(=O)/C(=C\C)/C)C(=C2[C@@H]3OC(=O)[C@@](C)(O)[C@@]3(O)[C@H](C[C@](C)(OC(=O)C)[C@@H]12)OC(=O)CCC)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L04 compound treatment 200.0 -2170.0 -0.93 3560.0 -883.0 -0.41 -0.9465 -0.9305 407 Bio2_000702 [O-][N+](=O)c1cccc2c(Br)n[nH]c12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L05 compound treatment 1560.0 -809.0 -0.35 3080.0 -1360.0 -0.63 -0.689 -0.9615 392 Bio2_000703 CCN(CC)CCCCCCCOC(=O)c1cc(OC)c(OC)c(OC)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L06 compound treatment 3280.0 911.0 0.39 3240.0 -1200.0 -0.55 -0.1139 -0.1681 3103965 Bio2_000704 Nc1ncnc2n(C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3O)c(Br)nc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L07 compound treatment 7520.0 5150.0 2.22 4280.0 -163.0 -0.07 1.5136 0.6829 196 Bio2_000705 Cc1ccc(cc1)S(=O)(=O)NC(=O)NN2CCCCCC2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L08 compound treatment 8000.0 5630.0 2.42 3880.0 -563.0 -0.26 1.5295 0.628 3103966 Bio2_000706 NC1=NC2C(N=C(Br)N2C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3O)C(=O)N1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L09 compound treatment 4440.0 2070.0 0.89 4000.0 -443.0 -0.2 0.4859 0.5319 198 Bio2_000707 CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L10 compound treatment 4400.0 2030.0 0.87 3400.0 -1040.0 -0.48 0.2787 0.2797 404 Bio2_000708 CCCCNc1cc(cc(c1Oc2ccccc2)S(=O)(=O)N)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L11 compound treatment 4440.0 2070.0 0.89 2960.0 -1480.0 -0.68 0.1478 0.1318 3103746 Bio2_000709 C1CCC(CC1)/N=C(\NC2C3CC4CC(C3)CC2C4)/N5CCOCC5 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L12 compound treatment 2280.0 -88.9 -0.04 3080.0 -1360.0 -0.63 -0.47 -0.7489 3001884 Bio2_000710 CCNC(=O)[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)n2cnc3c(N)ncnc23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L13 compound treatment 2360.0 -8.89 0.0 2720.0 -1720.0 -0.79 -0.5628 -0.7105 396 Bio2_000711 CN([C@H]1CCCC[C@@H]1N2CCCC2)C(=O)Cc3ccc(Cl)c(Cl)c3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L14 compound treatment 2200.0 -169.0 -0.07 2640.0 -1800.0 -0.83 -0.6374 -0.7661 373 Bio2_000712 CC(/C=C/c1cccc(Oc2ccc(F)cc2)c1)N(O)C(=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L15 compound treatment 2720.0 351.0 0.15 2840.0 -1600.0 -0.74 -0.4143 -0.5508 1000056 Bio2_000713 COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L16 compound treatment 2880.0 511.0 0.22 2960.0 -1480.0 -0.68 -0.3266 -0.456 3103967 Bio2_000714 CCCNC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N2CCC[C@H]2C(=O)OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L17 compound treatment 3280.0 911.0 0.39 2320.0 -2120.0 -0.98 -0.413 -0.3927 200 Bio2_000715 COc1ccc(cc1OC)C(=O)OC2CC[C@@]3(C)C4CCC5[C@@]3(C[C@@]6(O)C7CN8CC(C)CCC8[C@@](C)(O)[C@@]7(O)[C@@H](O)C[C@@]56O)O[C@@]42O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L18 compound treatment 2720.0 351.0 0.15 2880.0 -1560.0 -0.72 -0.4013 -0.5466 1907757 Bio2_000716 Oc1ccc(NC2=C(C(=O)NC2=O)c3ccccc3[N+](=O)[O-])cc1Cl 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L19 compound treatment 3160.0 791.0 0.34 2640.0 -1800.0 -0.83 -0.3455 -0.3856 202 Bio2_000717 COc1ccc(CCN(C)CCc2ccc(OC)c(OC)c2)cc1OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L20 compound treatment 2560.0 191.0 0.08 2640.0 -1800.0 -0.83 -0.528 -0.6339 3103968 Bio2_000718 CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L21 compound treatment 2960.0 591.0 0.25 3400.0 -1040.0 -0.48 -0.1592 -0.2934 3104544 Bio2_000719 CC(O)(C(=O)Nc1ccccc1)C(F)(F)F.CS(=O)(=O)c1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L22 compound treatment 2600.0 231.0 0.1 3360.0 -1080.0 -0.5 -0.2817 -0.555 125 Bio2_000720 COc1cc(O)c2c(=O)c(OC)c(CC(C)OC(=O)Oc3ccc(O)cc3)c4c5c(CC(C)OC(=O)c6ccccc6)c(OC)c(=O)c7c(O)cc(OC)c(c1c24)c75 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L23 mock treatment 3840.0 1470.0 0.63 3480.0 -963.0 -0.44 0.1344 0.1741 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 L24 mock treatment 120.0 -2250.0 -0.97 200.0 -4240.0 -1.95 -2.0633 -0.9476 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M01 mock treatment 4280.0 1910.0 0.82 5000.0 557.0 0.26 0.7624 0.8856 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M02 mock treatment 6160.0 3790.0 1.63 5040.0 597.0 0.27 1.3471 0.8148 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M03 compound treatment 6360.0 3990.0 1.72 3880.0 -563.0 -0.26 1.0308 0.5938 53 Bio2_000721 CC(=CCC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M04 compound treatment 6000.0 3630.0 1.56 4040.0 -403.0 -0.19 0.9734 0.619 189 Bio2_000722 CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M05 compound treatment 5000.0 2630.0 1.13 3600.0 -843.0 -0.39 0.5262 0.4399 51 Bio2_000723 CC(=CCC/C(=C/CC/C(=C/CC/C(=C/CSC[C@H](NC(=O)C)C(=O)O)/C)/C)/C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M06 compound treatment 4440.0 2070.0 0.89 3240.0 -1200.0 -0.55 0.2388 0.2278 49 Bio2_000724 COC(=O)[C@@H](N)CSC/C=C(\C)/CC/C=C(\C)/CCC=C(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M07 compound treatment 3800.0 1430.0 0.62 3560.0 -883.0 -0.41 0.1483 0.2011 116 Bio2_000725 Cc1c(nn(c1c2ccc(I)cc2)c3ccc(Cl)cc3Cl)C(=O)NN4CCCCC4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M08 compound treatment 3760.0 1390.0 0.6 2680.0 -1760.0 -0.81 -0.15 -0.1489 1000032 Bio2_000726 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M09 compound treatment 3560.0 1190.0 0.51 3000.0 -1440.0 -0.66 -0.1068 -0.1274 132 Bio2_000727 CC1(C)CCC(C)(C)c2cc(ccc21)C(=O)Nc3ccc(cc3)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M10 compound treatment 4440.0 2070.0 0.89 3240.0 -1200.0 -0.55 0.2388 0.2278 3103969 Bio2_000728 OC(=O)CCC/C=C\CC1C(CNNC(=O)Nc2ccccc2)C3CCC1O3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M11 compound treatment 3800.0 1430.0 0.62 2720.0 -1720.0 -0.79 -0.1249 -0.1245 2 Bio2_000729 CCCCC/C=C\C/C=C\CCCCCCCC(=O)NCCO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M12 compound treatment 2760.0 391.0 0.17 2920.0 -1520.0 -0.7 -0.3761 -0.5224 3001885 Bio2_000730 CCCCCc1cc(O)c2C3C=C(CC[C@H]3C(C)(C)Oc2c1)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M13 compound treatment 2840.0 471.0 0.2 3600.0 -843.0 -0.39 -0.1307 -0.2989 4 Bio2_000731 CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)NCCO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M14 compound treatment 2360.0 -8.89 0.0 2440.0 -2000.0 -0.92 -0.6538 -0.71 134 Bio2_000732 C/C(=C\c1ccc(cc1)C(=O)O)/c2ccc3c(c2)C(C)(C)CCC3(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M15 compound treatment 2960.0 591.0 0.25 2720.0 -1720.0 -0.79 -0.3803 -0.4572 316 Bio2_000733 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M16 compound treatment 3360.0 991.0 0.43 3760.0 -683.0 -0.31 0.0795 0.1502 261 Bio2_000734 CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@H]2CO[C@@H]1C2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M17 compound treatment 2680.0 311.0 0.13 2800.0 -1640.0 -0.76 -0.4394 -0.5729 6 Bio2_000735 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)NCCO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M18 compound treatment 2720.0 351.0 0.15 2760.0 -1680.0 -0.77 -0.4403 -0.5586 3103970 Bio2_000736 CCCCC/C=C\CC(O)/C=C/c1cccc(CC(O)CCCCO)n1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M19 compound treatment 2840.0 471.0 0.2 3080.0 -1360.0 -0.63 -0.2997 -0.4552 20 Bio2_000737 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M20 compound treatment 3080.0 711.0 0.31 2640.0 -1800.0 -0.83 -0.3698 -0.4186 18 Bio2_000738 Cc1c(C(=O)c2ccc3ccccc3c2)c4cccc5OC[C@@H](CN6CCOCC6)n1c54 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M21 compound treatment 2760.0 391.0 0.17 3400.0 -1040.0 -0.48 -0.22 -0.4331 225 Bio2_000739 CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M22 compound treatment 3080.0 711.0 0.31 3680.0 -763.0 -0.35 -0.0317 -0.0681 138 Bio2_000740 Cc1cccc(Nc2cc(Cl)nc(SCC(=O)O)n2)c1C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M23 mock treatment 3360.0 991.0 0.43 4480.0 37.4 0.02 0.3136 0.7351 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 M24 mock treatment 120.0 -2250.0 -0.97 160.0 -4280.0 -1.97 -2.0763 -0.9464 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N01 mock treatment 160.0 -2210.0 -0.95 3680.0 -763.0 -0.35 -0.9197 -0.9082 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N02 mock treatment 6200.0 3830.0 1.65 4520.0 77.4 0.04 1.1902 0.7222 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N03 compound treatment 1120.0 -1250.0 -0.54 840.0 -3600.0 -1.66 -1.5511 -0.8907 1002014 Bio2_000741 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)CCl 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N04 compound treatment 280.0 -2090.0 -0.9 280.0 -4160.0 -1.91 -1.9886 -0.9405 3103971 Bio2_000742 COC[C@H]([C@@H](O)[C@@H](O)C(=O)NCC[C@@H](C)c1nc(/C=C/C[C@H]2OC3(C[C@H](O)[C@H]2C)OC([C@@H](C[C@@H](O)[C@@H](C)[C@@H](O)[C@@H](C)/C=C(\C)/C(=C/C=C/C(=C\C#N)/C)/C)OC)[C@@H](OP(=O)(O)O)C3(C)C)co1)N(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N05 compound treatment 6440.0 4070.0 1.75 4160.0 -283.0 -0.13 1.1462 0.6528 2041 Bio2_000743 OC(=O)CNC(=O)C(CS)Cc1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N06 compound treatment 240.0 -2130.0 -0.92 280.0 -4160.0 -1.91 -2.0008 -0.943 3001887 Bio2_000744 CC[C@@]1(O)C(=O)OCc2c1cc3Cc4nc5ccccc5cc4-n3c2=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N07 compound treatment 3240.0 871.0 0.37 3560.0 -883.0 -0.41 -0.022 -0.0399 831924 Bio2_000745 O=C[C@@H]1CCCN1C(=O)[C@@H]2CCCN2C(=O)OCc3ccccc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N08 compound treatment 2160.0 -209.0 -0.09 2600.0 -1840.0 -0.85 -0.6626 -0.7777 363 Bio2_000746 CC12C3CCC(O3)C2(C)C(=O)OC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N09 compound treatment 3960.0 1590.0 0.68 2800.0 -1640.0 -0.76 -0.0502 -0.0492 1907758 Bio2_000747 CCC(C)[C@H](NS(=O)(=O)c1cccc2ccccc12)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N10 compound treatment 3800.0 1430.0 0.62 2440.0 -2000.0 -0.92 -0.2159 -0.1949 446 Bio2_000748 COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N11 compound treatment 480.0 -1890.0 -0.81 720.0 -3720.0 -1.71 -1.7848 -0.942 1891 Bio2_000749 Clc1oc(=O)c2ccccc2c1Cl 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N12 compound treatment 2240.0 -129.0 -0.06 2360.0 -2080.0 -0.96 -0.7163 -0.7468 377 Bio2_000750 Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc3ccc(Cl)cc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N13 compound treatment 2840.0 471.0 0.2 2640.0 -1800.0 -0.83 -0.4428 -0.519 1907759 Bio2_000751 CC(C)[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)OC(C)(C)C)C(C)C)C=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N14 compound treatment 2920.0 551.0 0.24 3440.0 -1000.0 -0.46 -0.1584 -0.3055 379 Bio2_000752 O[C@H]1CCN2C[C@H](O)[C@@H](O)[C@H](O)[C@@H]12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N15 compound treatment 2800.0 431.0 0.19 2960.0 -1480.0 -0.68 -0.3509 -0.4967 2060 Bio2_000753 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N16 compound treatment 2640.0 271.0 0.12 2800.0 -1640.0 -0.76 -0.4516 -0.5909 3103975 Bio2_000754 CCCN(CCC)c1nc(N2CCCCC2)c3nc(nc(N4CCCCC4)c3n1)N(CCC)CCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N17 compound treatment 2360.0 -8.89 0.0 3960.0 -483.0 -0.22 -0.1596 -0.7192 1907760 Bio2_000755 C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)CCl 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N18 compound treatment 2440.0 71.1 0.03 2720.0 -1720.0 -0.79 -0.5384 -0.6793 391 Bio2_000756 Clc1ccc2NC(=O)CSC(c3ccccc3Cl)c2c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N19 compound treatment 3040.0 671.0 0.29 2640.0 -1800.0 -0.83 -0.382 -0.4352 1907761 Bio2_000757 CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc2ccccc2)C=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N20 compound treatment 80.0 -2290.0 -0.98 160.0 -4280.0 -1.97 -2.0885 -0.9487 3001890 Bio2_000758 COc1ccc2c(c1)c(OC)[n+](C)c3c2ccc4cc5OCOc5cc43 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N21 compound treatment 2040.0 -329.0 -0.14 3200.0 -1240.0 -0.57 -0.504 -0.8563 1907762 Bio2_000759 CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C)C=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N22 compound treatment 3160.0 791.0 0.34 2920.0 -1520.0 -0.7 -0.2545 -0.3269 1907763 Bio2_000760 Oc1ccc(/C=C/C(=O)OCCc2ccccc2)cc1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N23 mock treatment 3600.0 1230.0 0.53 4320.0 -123.0 -0.06 0.3345 0.6283 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 N24 mock treatment 200.0 -2170.0 -0.93 120.0 -4320.0 -1.99 -2.065 -0.9405 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O01 mock treatment 6560.0 4190.0 1.8 4560.0 117.0 0.05 1.3127 0.728 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O02 mock treatment 6440.0 4070.0 1.75 5640.0 1200.0 0.55 1.6274 0.8867 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O03 compound treatment 4720.0 2350.0 1.01 4520.0 77.4 0.04 0.7402 0.7316 73 Bio2_000761 CCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O04 compound treatment 4320.0 1950.0 0.84 4360.0 -82.6 -0.04 0.5665 0.6744 338 Bio2_000762 Nc1ccncc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O05 compound treatment 4760.0 2390.0 1.03 4040.0 -403.0 -0.19 0.5963 0.5707 12 Bio2_000763 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)N4CCOCC4)c2c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O06 compound treatment 3760.0 1390.0 0.6 3640.0 -803.0 -0.37 0.1621 0.2306 340 Bio2_000764 CCCCCC(O)CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O07 compound treatment 3920.0 1550.0 0.67 3000.0 -1440.0 -0.66 0.0027 0.0028 305 Bio2_000765 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O08 compound treatment 3440.0 1070.0 0.46 2760.0 -1680.0 -0.77 -0.2213 -0.2458 1000039 Bio2_000766 CC[C@]1(COC)[C@H](O)C[C@H](OC)[C@@]2(C(C)C)C3C[C@@]4(O)[C@H](OC(=O)c5ccccc5)C3[C@](C[C@H](OC)C12)(OC(=O)C)[C@@H](O)C[C@@H]4OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O09 compound treatment 3440.0 1070.0 0.46 2800.0 -1640.0 -0.76 -0.2083 -0.2355 307 Bio2_000767 CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O10 compound treatment 3480.0 1110.0 0.48 2760.0 -1680.0 -0.77 -0.2092 -0.23 24 Bio2_000768 CN(CCc1ccc(Cl)c(Cl)c1)CC(O)COc2ccc(NS(=O)(=O)C)cc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O11 compound treatment 3720.0 1350.0 0.58 2680.0 -1760.0 -0.81 -0.1622 -0.1626 311 Bio2_000769 CCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](CO)NC(=O)CCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O12 compound treatment 2160.0 -209.0 -0.09 2560.0 -1880.0 -0.87 -0.6756 -0.7763 1000040 Bio2_000770 [N-2]C1(CC2CC3CC(C2)C1)C3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O13 compound treatment 2640.0 271.0 0.12 3040.0 -1400.0 -0.64 -0.3736 -0.57 313 Bio2_000771 CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(=O)CCCCCCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O14 compound treatment 3320.0 951.0 0.41 2640.0 -1800.0 -0.83 -0.2968 -0.3212 1000042 Bio2_000772 NC(=N)NC(=O)c1nc(Cl)c(N)nc1N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O15 compound treatment 3200.0 831.0 0.36 2560.0 -1880.0 -0.87 -0.3593 -0.3837 271 Bio2_000773 CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)C[C@@H]2C/C(=C\CCCC(=O)O)/C[C@H]12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O16 compound treatment 2640.0 271.0 0.12 2520.0 -1920.0 -0.88 -0.5426 -0.6086 26 Bio2_000774 CCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O17 compound treatment 3160.0 791.0 0.34 2400.0 -2040.0 -0.94 -0.4235 -0.424 140 Bio2_000775 CC1(COc2ccc(CC3SC(=O)NC3=O)cc2)CCCCC1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O18 compound treatment 2680.0 311.0 0.13 2120.0 -2320.0 -1.07 -0.6605 -0.6137 28 Bio2_000776 CNc1ccc2oc(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)c5ccc[nH]5)[C@H](C)C[C@H]4C)nc2c1C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O19 compound treatment 2680.0 311.0 0.13 2760.0 -1680.0 -0.77 -0.4525 -0.5763 142 Bio2_000777 CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O20 compound treatment 2440.0 71.1 0.03 2720.0 -1720.0 -0.79 -0.5384 -0.6793 3103889 Bio2_000778 COC(=O)C1=C(C)NC(=C(O)C1c2ccccc2C(F)(F)F)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O21 compound treatment 3040.0 671.0 0.29 2600.0 -1840.0 -0.85 -0.395 -0.4413 219 Bio2_000779 O[C@@H](COc1cccc(Cl)c1)/C=C/[C@H]2[C@H](O)C[C@H](O)[C@@H]2C/C=C\CCCC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O22 compound treatment 3040.0 671.0 0.29 4600.0 157.0 0.07 0.2553 0.8579 3103678 Bio2_000780 N/C(=N\C(=O)c1nc(Cl)c(N)nc1N)/NCc2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O23 mock treatment 2800.0 431.0 0.19 3840.0 -603.0 -0.28 -0.0648 -0.1944 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 O24 mock treatment 160.0 -2210.0 -0.95 320.0 -4120.0 -1.9 -2.0121 -0.949 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P01 mock treatment 480.0 -1890.0 -0.81 6480.0 2040.0 0.94 0.088 0.071 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P02 mock treatment 240.0 -2130.0 -0.92 5080.0 637.0 0.29 -0.4401 -0.4578 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P03 compound treatment 4760.0 2390.0 1.03 4600.0 157.0 0.07 0.7783 0.755 1907764 Bio2_000781 CCCC[C@@H]1[C@@H](OC(=O)CC(C)C)[C@H](C)OC(=O)[C@@H](NC(=O)c2cccc(NC=O)c2OC)[C@@H](C)OC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P04 compound treatment 12520.0 10200.0 4.37 5760.0 1320.0 0.61 3.5154 0.7976 393 Bio2_000782 CC(C)NCC(O)c1ccc(N)c(C#N)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P05 compound treatment 2520.0 151.0 0.06 4080.0 -363.0 -0.17 -0.0719 -0.402 2090 Bio2_000783 CCOC(=O)C(C#N)C1C(=C(N)Oc2ccc(Br)cc12)C(=O)OCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P06 compound treatment 2600.0 231.0 0.1 4200.0 -243.0 -0.11 -0.0086 -0.0574 157 Bio2_000784 COC(=O)CC[C@H](NC(=O)CNC(=O)c1ccc(/C=C/C(=O)OC)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P07 compound treatment 2640.0 271.0 0.12 3480.0 -963.0 -0.44 -0.2305 -0.5036 2020 Bio2_000785 CCCCCCCCCCC1=C(C)C(=O)C(=C(OC)C1=O)OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P08 compound treatment 3000.0 631.0 0.27 3360.0 -1080.0 -0.5 -0.1601 -0.2823 395 Bio2_000786 C(Oc1ccccc1C2CC2)C3=NCCN3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P09 compound treatment 2560.0 191.0 0.08 2760.0 -1680.0 -0.77 -0.4889 -0.6284 3103891 Bio2_000787 CC(=C)C1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P10 compound treatment 3440.0 1070.0 0.46 3600.0 -843.0 -0.39 0.0518 0.086 448 Bio2_000788 Clc1cccc(Cl)c1N=C2NCCN2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P11 compound treatment 2680.0 311.0 0.13 2560.0 -1880.0 -0.87 -0.5175 -0.5908 1000476 Bio2_000789 C[C@@H](N(C)CC#C)c1ccccc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P12 compound treatment 2880.0 511.0 0.22 3120.0 -1320.0 -0.61 -0.2746 -0.4246 417 Bio2_000790 CN1CCN(CC1)C2=Nc3cc(Cl)ccc3Nc4ccccc24 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P13 compound treatment 3600.0 1230.0 0.53 2920.0 -1520.0 -0.7 -0.1207 -0.1375 410 Bio2_000791 CC(=N)NCc1cccc(CN)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P14 compound treatment 2280.0 -88.9 -0.04 2320.0 -2120.0 -0.98 -0.7172 -0.7342 3001893 Bio2_000792 COc1ccc(/C=C/C(=O)CC(=O)\C=C\c2cccc(O)c2OC)cc1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P15 compound treatment 2400.0 31.1 0.01 2720.0 -1720.0 -0.79 -0.5506 -0.6951 3001894 Bio2_000793 *[C@@H](C[C@@H](C)C[C@H](O)CCCC[C@@H](O)C[C@H](O)[C@H](C)N)[C@H](*)[C@H](C)CCCC.CC(=O)C[C@@H](CC(=O)O)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P16 compound treatment 320.0 -2050.0 -0.88 280.0 -4160.0 -1.91 -1.9765 -0.938 421 Bio2_000794 C[C@H]1C[C@H](C)C(=O)[C@@H](C1)[C@@H](O)CC2CC(=O)NC(=O)C2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P17 compound treatment 200.0 -2170.0 -0.93 120.0 -4320.0 -1.99 -2.065 -0.9405 2340 Bio2_000795 CC(C)[C@@]12O[C@H]2[C@@H]3O[C@]34[C@]5(O[C@H]5C[C@H]6C7=C(CC[C@@]64C)C(=O)OC7)[C@@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P18 compound treatment 2800.0 431.0 0.19 2480.0 -1960.0 -0.9 -0.507 -0.5503 3001895 Bio2_000796 *C1N(C)C(=O)C(*)N(C)C(=O)C(C)NC(=O)C(C)NC(=O)C(CC(C)C)N(C)C(=O)C(NC(=O)C(CC(C)C)N(C)C(=O)CN(C)C(=O)C(CC)NC(=O)C(C(O)C(C)C/C=C/C)N(C)C(=O)C(*)N(C)C1=O)C(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P19 compound treatment 2760.0 391.0 0.17 3480.0 -963.0 -0.44 -0.194 -0.4098 1907765 Bio2_000797 Cc1coc-2c1C(=O)C(=O)c3c4CCCC(C)(C)c4ccc23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P20 compound treatment 3720.0 1350.0 0.58 3680.0 -763.0 -0.35 0.1629 0.2401 397 Bio2_000798 CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)c2cccc(Oc3ccccc3)c2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P21 compound treatment 1840.0 -529.0 -0.23 2640.0 -1800.0 -0.83 -0.7469 -0.869 3103893 Bio2_000799 C[C@H]([C@@H]1O[C@@H](C[C@@H]2CC[C@@H](C)[C@@]3(O[C@@](C)(C[C@H]3C)[C@H]4CC[C@](C)(O4)[C@@H]5O[C@H](C[C@@H]5C)[C@H]6O[C@@](O)(CO)[C@H](C)C[C@@H]6C)O2)CC[C@@H]1C)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P22 compound treatment 2680.0 311.0 0.13 3440.0 -1000.0 -0.46 -0.2314 -0.482 3103894 Bio2_000800 C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@@]42OC(=O)/C=C/[C@H](O)CCC[C@@H](C)C\C=C\[C@H]4[C@H](O)C1=C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P23 mock treatment 3600.0 1230.0 0.53 3880.0 -563.0 -0.26 0.1915 0.3249 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2128 P24 mock treatment 160.0 -2210.0 -0.95 120.0 -4320.0 -1.99 -2.0772 -0.9429 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A01 mock treatment 4040.0 1510.0 0.65 4240.0 1170.0 0.54 0.8416 0.9957 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A02 mock treatment 4000.0 1470.0 0.63 4720.0 1650.0 0.76 0.9855 0.9959 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A03 compound treatment 6760.0 4230.0 1.82 5880.0 2810.0 1.29 2.202 0.986 3001896 Bio2_000801 C[C@H]1[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@@]24[C@@H](/C=C/C[C@H](C)C(=O)[C@@](C)(O)/C=C/[C@H]4OC(=O)C)[C@H](O)C1=C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A04 mock treatment 3600.0 1070.0 0.46 4200.0 1130.0 0.52 0.6948 0.9981 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A05 compound treatment 3960.0 1430.0 0.62 3360.0 294.0 0.14 0.5312 0.8421 236 Bio2_000802 SC(=S)OC1CC2CC1C3CCCC23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A06 mock treatment 2760.0 233.0 0.1 3880.0 814.0 0.37 0.3353 0.8658 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A07 compound treatment 3440.0 913.0 0.39 4440.0 1370.0 0.63 0.7242 0.9738 159 Bio2_000803 COc1c(C=O)c(O)cc2C(=O)c3ccccc3C(=O)c12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A08 mock treatment 2520.0 -7.32 0.0 3520.0 454.0 0.21 0.1453 0.6964 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A09 compound treatment 3200.0 673.0 0.29 3680.0 614.0 0.28 0.4041 0.9999 2370 Bio2_000804 OCc1ccc(o1)c2nn(Cc3ccccc3)c4ccccc24 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A10 mock treatment 2240.0 -287.0 -0.12 2920.0 -146.0 -0.07 -0.1349 -0.9591 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A11 compound treatment 2680.0 153.0 0.07 3520.0 454.0 0.21 0.194 0.8868 251 Bio2_000805 Nc1ncnc2n(cnc12)C3(CO)OC(=C)C(O)C3O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A12 mock treatment 2720.0 193.0 0.08 2560.0 -506.0 -0.23 -0.106 -0.429 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A13 compound treatment 3240.0 713.0 0.31 4280.0 1210.0 0.56 0.6114 0.9602 3001897 Bio2_000806 OC[C@H]1*C[C@@H](O)[C@@H](O)[C@@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A14 mock treatment 2280.0 -247.0 -0.11 3400.0 334.0 0.15 0.0333 0.1784 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A15 compound treatment 2680.0 153.0 0.07 3520.0 454.0 0.21 0.194 0.8868 1907766 Bio2_000807 OC[C@H]1*C[C@H](O)[C@@H](O)[C@@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A16 mock treatment 2240.0 -287.0 -0.12 3520.0 454.0 0.21 0.0602 0.2481 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A17 compound treatment 2880.0 353.0 0.15 3680.0 614.0 0.28 0.3068 0.9576 3103895 Bio2_000808 C[C@@H]1CC2C3CCC4=CC(=O)C=CC4(C)[C@@]3(F)[C@@H](O)CC2(C)[C@@]1(O)C(=O)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A18 mock treatment 2120.0 -407.0 -0.18 2800.0 -266.0 -0.12 -0.2104 -0.9847 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A19 compound treatment 2800.0 273.0 0.12 4400.0 1330.0 0.61 0.5166 0.8273 3103896 Bio2_000809 CCCC(=O)Nc1ncnc2n(cnc12)C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3OC(=O)CCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A20 mock treatment 2800.0 273.0 0.12 4000.0 934.0 0.43 0.3865 0.8684 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A21 compound treatment 3600.0 1070.0 0.46 4400.0 1330.0 0.61 0.7599 0.9902 3001899 Bio2_000810 CCCC(=O)Nc1nc2n(cnc2c(=O)[nH]1)C3O[C@H]4COP(=O)(O)O[C@@H]4[C@@H]3OC(=O)CCC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A22 mock treatment 3000.0 473.0 0.2 4240.0 1170.0 0.54 0.5254 0.911 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A23 mock treatment 3400.0 873.0 0.38 4080.0 1010.0 0.47 0.595 0.9942 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 A24 mock treatment 240.0 -2290.0 -0.98 240.0 -2830.0 -1.3 -1.6145 -0.9906 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B01 mock treatment 4080.0 1550.0 0.67 4840.0 1770.0 0.82 1.0489 0.9951 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B02 mock treatment 3880.0 1350.0 0.58 4360.0 1290.0 0.59 0.832 0.9999 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B03 compound treatment 10800.0 8270.0 3.56 11040.0 7970.0 3.67 5.1083 0.9999 440 Bio2_000811 COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3cccs3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B04 mock treatment 3240.0 713.0 0.31 4200.0 1130.0 0.52 0.5854 0.9679 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B05 compound treatment 3480.0 953.0 0.41 3840.0 774.0 0.36 0.5413 0.9975 442 Bio2_000812 CCCCCCCCCCCCCCCCCCc1ccc(cc1)C(=O)/C=C/C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B06 mock treatment 2960.0 433.0 0.19 3960.0 894.0 0.41 0.4222 0.9358 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B07 compound treatment 3240.0 713.0 0.31 4480.0 1410.0 0.65 0.6764 0.9411 3103897 Bio2_000813 C[C@@H](CC(O)[C@H]1OC2CC[C@@]3(CC[C@H](O3)/C=C/[C@@H](C)[C@@H]4CC(=C[C@@]5(O[C@H](C[C@@](C)(O)C(=O)O)CCC5O)O4)C)OC2[C@H](O)C1=C)C6O[C@@]7(CCCCO7)CC[C@H]6C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B08 mock treatment 2920.0 393.0 0.17 840.0 -2230.0 -1.02 -0.6044 -0.5826 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B09 compound treatment 120.0 -2410.0 -1.04 200.0 -2870.0 -1.32 -1.664 -0.9929 3104621 Bio2_000814 CC[C@H]/1CC[C@H]2O[C@@]3(CC[C@@H](C)[C@@H](C[C@H](C)O)O3)[C@H](C)[C@@H](OC(=O)/C=C/[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C(=O)[C@@](C)(O)[C@H](O)[C@@H](C)C\C=C\C=C1)[C@H]2C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B10 mock treatment 2640.0 113.0 0.05 3160.0 93.8 0.04 0.0647 0.9983 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B11 compound treatment 2800.0 273.0 0.12 3360.0 294.0 0.14 0.1784 0.9975 324 Bio2_000815 Cn1cnc2c(NCc3ccccc3)nc(NCCO)nc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B12 mock treatment 3080.0 553.0 0.24 3680.0 614.0 0.28 0.3676 0.9964 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B13 compound treatment 1080.0 -1450.0 -0.62 1240.0 -1830.0 -0.84 -1.0339 -0.9891 3103898 Bio2_000816 CC1OC(OC2CC(O)C3(CO)C4[C@H](O)CC5(C)C(CCC5(O)C4CCC3(O)C2)C6=CC(=O)OC6)C(O)C(O)C1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B14 mock treatment 2840.0 313.0 0.13 3760.0 694.0 0.32 0.3207 0.9263 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B15 compound treatment 2960.0 433.0 0.19 3360.0 294.0 0.14 0.2271 0.9876 444 Bio2_000817 COC(=O)C1=C(C)NC(=C(C1C)C(=O)OCCSc2ccccc2)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B16 mock treatment 2520.0 -7.32 0.0 3720.0 654.0 0.3 0.2103 0.6997 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B17 compound treatment 2520.0 -7.32 0.0 3640.0 574.0 0.26 0.1843 0.6986 453 Bio2_000818 COc1cccc(c1N)c2cc(=O)c3ccccc3o2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B18 mock treatment 2600.0 72.7 0.03 4160.0 1090.0 0.5 0.3777 0.7496 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B19 compound treatment 3120.0 593.0 0.25 3280.0 214.0 0.1 0.2497 0.9142 1907767 Bio2_000819 CN(C)c1ccc(/C=C/2\C(=O)Nc3ccccc23)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B20 mock treatment 2400.0 -127.0 -0.05 3960.0 894.0 0.41 0.2519 0.6075 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B21 compound treatment 2280.0 -247.0 -0.11 3360.0 294.0 0.14 0.0203 0.1181 387 Bio2_000820 CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CC(C)C)C(C)C)C(C)C)[C@@H](O)CC(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B22 mock treatment 2760.0 233.0 0.1 4400.0 1330.0 0.61 0.5044 0.8117 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B23 mock treatment 3440.0 913.0 0.39 3880.0 814.0 0.37 0.5421 0.9997 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 B24 mock treatment 120.0 -2410.0 -1.04 280.0 -2790.0 -1.28 -1.638 -0.9944 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C01 mock treatment 3560.0 1030.0 0.44 4440.0 1370.0 0.63 0.7607 0.9851 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C02 mock treatment 3680.0 1150.0 0.5 3960.0 894.0 0.41 0.6411 0.9957 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C03 compound treatment 3440.0 913.0 0.39 4200.0 1130.0 0.52 0.6462 0.9902 1907768 Bio2_000821 [O-][N+](=O)c1ccc(Cl)c(c1)C(=O)Nc2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C04 mock treatment 2720.0 193.0 0.08 4240.0 1170.0 0.54 0.4402 0.8062 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C05 compound treatment 2800.0 273.0 0.12 4640.0 1570.0 0.72 0.5946 0.8111 1907769 Bio2_000822 *C1CCc2cc(O)c(O)cc2C1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C06 mock treatment 3000.0 473.0 0.2 4640.0 1570.0 0.72 0.6554 0.872 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C07 compound treatment 2480.0 -47.3 -0.02 3800.0 734.0 0.34 0.2242 0.6632 2098 Bio2_000823 CC(C)c1cccc(=O)c(O)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C08 mock treatment 2160.0 -367.0 -0.16 3480.0 414.0 0.19 0.0228 0.0923 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C09 compound treatment 120.0 -2410.0 -1.04 120.0 -2950.0 -1.35 -1.69 -0.9912 411 Bio2_000824 [I+]1c2ccccc2-c3ccccc13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C10 mock treatment 2920.0 393.0 0.17 3160.0 93.8 0.04 0.1499 0.86 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C11 compound treatment 3280.0 753.0 0.32 4280.0 1210.0 0.56 0.6235 0.9664 1961 Bio2_000825 CC(C)(C)c1cc(O)c(cc1O)C(C)(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C12 mock treatment 2600.0 72.7 0.03 3880.0 814.0 0.37 0.2867 0.7635 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C13 compound treatment 240.0 -2290.0 -0.98 360.0 -2710.0 -1.24 -1.5755 -0.9932 3103899 Bio2_000826 COc1cccc2C(=O)C3C(C(=C4[C@H](C[C@@](O)(CC4=C3O)C(=O)CO)OC5CC(N)C(O)C(C)O5)O)C(=O)c12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C14 mock treatment 3240.0 713.0 0.31 3160.0 93.8 0.04 0.2472 0.7987 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C15 compound treatment 2000.0 -527.0 -0.23 2880.0 -186.0 -0.09 -0.2209 -0.9113 3000146 Bio2_000827 OC[C@H]1O[C@H](C(O)[C@H]1O)n2cnc3cc(Cl)c(Cl)cc23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C16 mock treatment 2080.0 -447.0 -0.19 3040.0 -26.3 -0.01 -0.1446 -0.75 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C17 compound treatment 2320.0 -207.0 -0.09 2840.0 -226.0 -0.1 -0.1366 -0.9971 3103900 Bio2_000828 OC(=O)c1ccc(cc1)C2=C3C=CC4=[N+]3[Mn+3]5([N+]6=C7C=CC6=C(c8ccc2n85)c9ccc(cc9)C(=O)O)n%10c(=C4c%11ccc(cc%11)C(=O)O)ccc%10=C7c%12ccc(cc%12)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C18 mock treatment 2160.0 -367.0 -0.16 3560.0 494.0 0.23 0.0488 0.1766 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C19 compound treatment 2400.0 -127.0 -0.05 3440.0 374.0 0.17 0.0828 0.4591 3002358 Bio2_000829 COc1cc2CCN(C)[C@@H]3Cc4ccc(OC(=O)c5ccc(cc5)[N+](=O)[O-])c(Oc6ccc(C[C@@H]7N(C)CCc8ccc(Oc(c1OC)c32)cc78)cc6)c4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C20 mock treatment 2240.0 -287.0 -0.12 4040.0 974.0 0.45 0.2292 0.4935 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C21 compound treatment 3200.0 673.0 0.29 3400.0 334.0 0.15 0.3131 0.956 3002360 Bio2_000830 *[C@H]1O[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCCC(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C22 mock treatment 2440.0 -87.3 -0.04 4160.0 1090.0 0.5 0.3291 0.6525 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C23 mock treatment 3280.0 753.0 0.32 3760.0 694.0 0.32 0.4545 1.0 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 C24 mock treatment 200.0 -2330.0 -1.0 320.0 -2750.0 -1.26 -1.6007 -0.9934 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D01 mock treatment 3880.0 1350.0 0.58 4040.0 974.0 0.45 0.728 0.9916 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D02 mock treatment 3240.0 713.0 0.31 4200.0 1130.0 0.52 0.5854 0.9679 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D03 compound treatment 3320.0 793.0 0.34 3680.0 614.0 0.28 0.4406 0.9956 384 Bio2_000831 O=c1[nH]c2ccccc2c3ccccc13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D04 mock treatment 3120.0 593.0 0.25 4680.0 1610.0 0.74 0.7049 0.8985 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D05 compound treatment 5200.0 2670.0 1.15 5400.0 2330.0 1.07 1.5716 0.9994 290 Bio2_000832 CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@]2(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)CC(=C[C@H]2[C@@H]4C(C)(C)[C@@]41OC(=O)C)CO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D06 mock treatment 2320.0 -207.0 -0.09 3440.0 374.0 0.17 0.0585 0.302 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D07 compound treatment 1680.0 -847.0 -0.36 2200.0 -866.0 -0.4 -0.5393 -0.999 455 Bio2_000833 Cc1ccc(cc1)C(=O)Cn2c3CCCCc3sc2=N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D08 mock treatment 2520.0 -7.32 0.0 3880.0 814.0 0.37 0.2624 0.7011 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D09 compound treatment 2240.0 -287.0 -0.12 2720.0 -346.0 -0.16 -0.2 -0.9922 1907770 Bio2_000834 Clc1ccc(cc1)c2nc3sccn3c2/C=N/OCc4ccc(Cl)c(Cl)c4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D10 mock treatment 2440.0 -87.3 -0.04 3320.0 254.0 0.12 0.0559 0.4565 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D11 compound treatment 2480.0 -47.3 -0.02 2800.0 -266.0 -0.12 -0.101 -0.8135 347 Bio2_000835 CN1C(=C(O)c2ccccc2S1(=O)=O)C(=O)Nc3ccccn3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D12 mock treatment 2760.0 233.0 0.1 3640.0 574.0 0.26 0.2573 0.9119 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D13 compound treatment 2680.0 153.0 0.07 3560.0 494.0 0.23 0.207 0.8757 1907771 Bio2_000836 CC1[C@@H]2NC[C@@H](C)C[C@H]2O[C@@]31CC[C@H]4[C@@H]5CC=C6C[C@@H](O)CC[C@]6(C)[C@H]5CC4=C3C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D14 mock treatment 2400.0 -127.0 -0.05 3440.0 374.0 0.17 0.0828 0.4591 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D15 compound treatment 3360.0 833.0 0.36 4480.0 1410.0 0.65 0.7129 0.9605 275745 Bio2_000837 Cc1ccc(cc1)c2nn(c3ncnc(N)c23)C(C)(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D16 mock treatment 1960.0 -567.0 -0.24 3400.0 334.0 0.15 -0.064 -0.2221 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D17 compound treatment 2200.0 -327.0 -0.14 3680.0 614.0 0.28 0.1 0.3171 349 Bio2_000838 COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4ccco4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D18 mock treatment 2200.0 -327.0 -0.14 2400.0 -666.0 -0.31 -0.3162 -0.9378 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D19 compound treatment 2160.0 -367.0 -0.16 3000.0 -66.3 -0.03 -0.1332 -0.8282 244 Bio2_000839 CC[N+](C)(CC)CCC[n+]1c(c2ccccc2)c3cc(N)ccc3c4ccc(N)cc14 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D20 mock treatment 2720.0 193.0 0.08 3680.0 614.0 0.28 0.2581 0.8777 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D21 compound treatment 2560.0 32.7 0.01 3640.0 574.0 0.26 0.1965 0.7437 3002368 Bio2_000840 CC(C)NC[C@H](O)COc1cccc2ccccc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D22 mock treatment 3200.0 673.0 0.29 3360.0 294.0 0.14 0.3001 0.9399 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D23 mock treatment 3240.0 713.0 0.31 4040.0 974.0 0.45 0.5333 0.9829 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 D24 mock treatment 160.0 -2370.0 -1.02 160.0 -2910.0 -1.34 -1.6648 -0.991 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E01 mock treatment 4040.0 1510.0 0.65 4240.0 1170.0 0.54 0.8416 0.9957 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E02 mock treatment 3280.0 753.0 0.32 3960.0 894.0 0.41 0.5195 0.993 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E03 compound treatment 3360.0 833.0 0.36 4320.0 1250.0 0.58 0.6609 0.9738 413 Bio2_000841 CCCCCC[C@@H]([C@@H](C)O)n1cnc2c(N)ncnc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E04 mock treatment 2520.0 -7.32 0.0 4040.0 974.0 0.45 0.3144 0.7021 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E05 compound treatment 2720.0 193.0 0.08 3080.0 13.8 0.01 0.0631 0.7589 1907772 Bio2_000842 CC(=O)[C@H]1[C@@H](CC2C3CC=C4C[C@@H](O)CCC4(C)C3CCC12C)C#N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E06 mock treatment 2480.0 -47.3 -0.02 2760.0 -306.0 -0.14 -0.114 -0.801 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E07 compound treatment 2520.0 -7.32 0.0 3280.0 214.0 0.1 0.0673 0.6841 386 Bio2_000843 C[C@@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]2CC[C@@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E08 mock treatment 2480.0 -47.3 -0.02 3240.0 174.0 0.08 0.0421 0.5107 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E09 compound treatment 2280.0 -247.0 -0.11 2080.0 -986.0 -0.45 -0.3959 -0.8499 2080384 Bio2_000844 COc1cc(cc(OC)c1O)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](OC4OC5COC(C)OC5C(O)C4O)c6cc7OCOc7cc26 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E10 mock treatment 2440.0 -87.3 -0.04 3040.0 -26.3 -0.01 -0.0351 -0.8896 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E11 compound treatment 120.0 -2410.0 -1.04 160.0 -2910.0 -1.34 -1.677 -0.992 415 Bio2_000845 FC(F)(F)Oc1ccc(NN=C(C#N)C#N)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E12 mock treatment 2120.0 -407.0 -0.18 3360.0 294.0 0.14 -0.0284 -0.1282 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E13 compound treatment 2920.0 393.0 0.17 3920.0 854.0 0.39 0.397 0.929 3002452 Bio2_000846 CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E14 mock treatment 2600.0 72.7 0.03 2600.0 -466.0 -0.21 -0.1295 -0.5977 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E15 compound treatment 1760.0 -767.0 -0.33 2080.0 -986.0 -0.45 -0.554 -0.9878 3104393 Bio2_000847 CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)/C(=C/C=C\[C@H](OC)[C@@H](OC(=O)N)/C(=C/[C@H](C)[C@H]1O)/C)/C)C2=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E16 mock treatment 2520.0 -7.32 0.0 3000.0 -66.3 -0.03 -0.0238 -0.7761 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E17 compound treatment 3000.0 473.0 0.2 2720.0 -346.0 -0.16 0.0312 0.1207 3103903 Bio2_000848 Cc1ccc(cc1)C2=CCc3cc(C)cc(C)c3C2=C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E18 mock treatment 2240.0 -287.0 -0.12 2480.0 -586.0 -0.27 -0.278 -0.9374 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E19 compound treatment 120.0 -2410.0 -1.04 360.0 -2710.0 -1.24 -1.612 -0.9958 576 Bio2_000849 Cn1cc(C2=C(C(=O)NC2=O)c3cn(CCCSC(=N)N)c4ccccc34)c5ccccc15 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E20 mock treatment 2360.0 -167.0 -0.07 3680.0 614.0 0.28 0.1487 0.5105 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E21 compound treatment 2760.0 233.0 0.1 3400.0 334.0 0.15 0.1793 0.9785 162 Bio2_000850 CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E22 mock treatment 2840.0 313.0 0.13 3720.0 654.0 0.3 0.3076 0.9342 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E23 mock treatment 3360.0 833.0 0.36 3760.0 694.0 0.32 0.4788 0.9983 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 E24 mock treatment 160.0 -2370.0 -1.02 160.0 -2910.0 -1.34 -1.6648 -0.991 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F01 mock treatment 3160.0 633.0 0.27 4040.0 974.0 0.45 0.509 0.9715 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F02 mock treatment 3280.0 753.0 0.32 4240.0 1170.0 0.54 0.6105 0.9701 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F03 compound treatment 440.0 -2090.0 -0.9 640.0 -2430.0 -1.12 -1.4236 -0.9942 3002455 Bio2_000851 *[C@H]1O[C@H]([C@H](O)[C@@H]1NC(=O)C(N)Cc2ccccc2)n3cnc4c(ncnc34)N(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F04 mock treatment 2760.0 233.0 0.1 3760.0 694.0 0.32 0.2963 0.8863 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F05 compound treatment 2000.0 -527.0 -0.23 3400.0 334.0 0.15 -0.0518 -0.1893 1907773 Bio2_000852 NC(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccc4OCOc4c3)c5ccccn5 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F06 mock treatment 2320.0 -207.0 -0.09 3400.0 334.0 0.15 0.0455 0.2562 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F07 compound treatment 2840.0 313.0 0.13 3160.0 93.8 0.04 0.1256 0.8892 1000035 Bio2_000853 O=C1c2ccccc2-c3n[nH]c4cccc1c34 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F08 mock treatment 2480.0 -47.3 -0.02 3080.0 13.8 0.01 -0.0099 -0.4655 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F09 compound treatment 2000.0 -527.0 -0.23 2400.0 -666.0 -0.31 -0.377 -0.989 353 Bio2_000854 Oc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F10 mock treatment 2440.0 -87.3 -0.04 2600.0 -466.0 -0.21 -0.1782 -0.8185 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F11 compound treatment 1840.0 -687.0 -0.3 2440.0 -626.0 -0.29 -0.4126 -0.9999 3104890 Bio2_000855 CO[C@@H]1CC(CC(C)[C@@H]2CC(=O)[C@H](C)/C=C(\C)/[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)/C=C/C=C/C=C(\C)/[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)OC)CC[C@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F12 mock treatment 2240.0 -287.0 -0.12 2880.0 -186.0 -0.09 -0.1479 -0.984 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F13 compound treatment 2280.0 -247.0 -0.11 3240.0 174.0 0.08 -0.0187 -0.1407 1907774 Bio2_000856 CC(C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F14 mock treatment 2600.0 72.7 0.03 2920.0 -146.0 -0.07 -0.0254 -0.3432 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F15 compound treatment 2360.0 -167.0 -0.07 2800.0 -266.0 -0.12 -0.1375 -0.9679 285 Bio2_000857 O=C(NCCCCCCNC(=O)ON=C1CCCCC1)ON=C2CCCCC2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F16 mock treatment 2600.0 72.7 0.03 2400.0 -666.0 -0.31 -0.1945 -0.6317 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F17 compound treatment 2800.0 273.0 0.12 2480.0 -586.0 -0.27 -0.1077 -0.3663 151 Bio2_000858 CCCCCCCCCCCCCCCC(=O)C1=C(O)C(CO)OC1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F18 mock treatment 2360.0 -167.0 -0.07 2800.0 -266.0 -0.12 -0.1375 -0.9679 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F19 compound treatment 2080.0 -447.0 -0.19 2400.0 -666.0 -0.31 -0.3527 -0.9749 291 Bio2_000859 CC[C@H](CO)Nc1nc(NCc2ccccc2)c3ncn(C(C)C)c3n1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F20 mock treatment 2520.0 -7.32 0.0 3280.0 214.0 0.1 0.0673 0.6841 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F21 compound treatment 920.0 -1610.0 -0.69 1680.0 -1390.0 -0.64 -0.9395 -0.9992 320 Bio2_000860 CC(=O)c1c(O)c(C)c(O)c(Cc2c(O)c(C(=O)/C=C/c3ccccc3)c4OC(C)(C)C=Cc4c2O)c1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F22 mock treatment 3080.0 553.0 0.24 3800.0 734.0 0.34 0.4066 0.9853 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F23 mock treatment 2680.0 153.0 0.07 3640.0 574.0 0.26 0.233 0.857 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 F24 mock treatment 200.0 -2330.0 -1.0 280.0 -2790.0 -1.28 -1.6137 -0.9925 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G01 mock treatment 3280.0 753.0 0.32 4320.0 1250.0 0.58 0.6365 0.9628 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G02 mock treatment 3160.0 633.0 0.27 3800.0 734.0 0.34 0.431 0.9943 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G03 compound treatment 2040.0 -487.0 -0.21 2480.0 -586.0 -0.27 -0.3388 -0.9923 152 Bio2_000861 Cn1c2ccccc2c3c4C(=O)NCc4c5c6ccccc6n(CCC#N)c5c13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G04 mock treatment 2320.0 -207.0 -0.09 2920.0 -146.0 -0.07 -0.1106 -0.9903 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G05 compound treatment 2160.0 -367.0 -0.16 3040.0 -26.3 -0.01 -0.1202 -0.7589 1298 Bio2_000862 CS(=O)(=O)Nc1ccc(cc1Oc2ccccc2)[N+](=O)[O-] 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G06 mock treatment 2680.0 153.0 0.07 3000.0 -66.3 -0.03 0.0249 0.3439 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G07 compound treatment 2000.0 -527.0 -0.23 2040.0 -1030.0 -0.47 -0.494 -0.9436 414 Bio2_000863 CC1CNCCN1S(=O)(=O)c2cccc3cnccc23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G08 mock treatment 2560.0 32.7 0.01 3200.0 134.0 0.06 0.0534 0.8469 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G09 compound treatment 2000.0 -527.0 -0.23 1800.0 -1270.0 -0.58 -0.5721 -0.9155 607 Bio2_000864 Brc1ccc(/C=C/CNCCNS(=O)(=O)c2cccc3cnccc23)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G10 mock treatment 2360.0 -167.0 -0.07 3240.0 174.0 0.08 0.0056 0.0522 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G11 compound treatment 2240.0 -287.0 -0.12 2720.0 -346.0 -0.16 -0.2 -0.9922 3002468 Bio2_000865 NCCNOc1cccc2cnccc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G12 mock treatment 2320.0 -207.0 -0.09 2760.0 -306.0 -0.14 -0.1626 -0.9757 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G13 compound treatment 2040.0 -487.0 -0.21 1920.0 -1150.0 -0.53 -0.5209 -0.9183 610 Bio2_000866 O=S(=O)(N1CCCNCC1)c2cccc3cnccc23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G14 mock treatment 2000.0 -527.0 -0.23 2480.0 -586.0 -0.27 -0.351 -0.9963 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G15 compound treatment 2480.0 -47.3 -0.02 2200.0 -866.0 -0.4 -0.296 -0.7423 609 Bio2_000867 NC(=N)NCCNS(=O)(=O)c1cccc2cnccc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G16 mock treatment 1560.0 -967.0 -0.42 2040.0 -1030.0 -0.47 -0.6278 -0.998 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G17 compound treatment 1840.0 -687.0 -0.3 1960.0 -1110.0 -0.51 -0.5687 -0.9667 611 Bio2_000868 COCc1cc(O)c(O)c(O)c1c2c(O)c(O)c(O)cc2COC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G18 mock treatment 2200.0 -327.0 -0.14 2360.0 -706.0 -0.32 -0.3292 -0.93 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G19 compound treatment 2440.0 -87.3 -0.04 3000.0 -66.3 -0.03 -0.0481 -0.9946 465 Bio2_000869 NCCc1c[nH]cn1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G20 mock treatment 2240.0 -287.0 -0.12 3520.0 454.0 0.21 0.0602 0.2481 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G21 compound treatment 1000.0 -1530.0 -0.66 1400.0 -1670.0 -0.77 -1.0062 -0.9971 239 Bio2_000870 CC(=O)OCOC(c1ccc2ccccc2c1)P(=O)(OCOC(=O)C)OCOC(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G22 mock treatment 3000.0 473.0 0.2 3120.0 53.8 0.02 0.1612 0.7873 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G23 mock treatment 3160.0 633.0 0.27 3720.0 654.0 0.3 0.405 0.9988 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 G24 mock treatment 200.0 -2330.0 -1.0 200.0 -2870.0 -1.32 -1.6397 -0.9908 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H01 mock treatment 3640.0 1110.0 0.48 3880.0 814.0 0.37 0.603 0.9926 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H02 mock treatment 3160.0 633.0 0.27 3960.0 894.0 0.41 0.483 0.98 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H03 compound treatment 840.0 -1690.0 -0.73 1600.0 -1470.0 -0.67 -0.9899 -0.9993 3104891 Bio2_000871 CC(=O)OCOC(P(=O)OCOC(=O)C)c1cc(ccc1Oc2ccc(Br)cc2)[N+](=O)[O-] 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H04 mock treatment 2480.0 -47.3 -0.02 3400.0 334.0 0.15 0.0941 0.608 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H05 compound treatment 2440.0 -87.3 -0.04 2920.0 -146.0 -0.07 -0.0741 -0.9621 1907775 Bio2_000872 CS(=O)(=O)c1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H06 mock treatment 2800.0 273.0 0.12 2800.0 -266.0 -0.12 -0.0036 -0.0215 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H07 compound treatment 2200.0 -327.0 -0.14 2720.0 -346.0 -0.16 -0.2121 -0.9981 457 Bio2_000873 Oc1ccc(cc1)c2nc(c([nH]2)c3ccncc3)c4ccc(F)cc4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H08 mock treatment 2280.0 -247.0 -0.11 2960.0 -106.0 -0.05 -0.1098 -0.9377 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H09 compound treatment 2440.0 -87.3 -0.04 2640.0 -426.0 -0.2 -0.1651 -0.8275 1000586 Bio2_000874 O/N=C\1/C(=C\2/C(=O)Nc3ccccc23)/Nc4ccccc14 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H10 mock treatment 2640.0 113.0 0.05 3320.0 254.0 0.12 0.1168 0.9242 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H11 compound treatment 2160.0 -367.0 -0.16 2120.0 -946.0 -0.44 -0.4194 -0.906 3104892 Bio2_000875 O=C/1Nc2ccccc2\C1=C/3\Nc4ccccc4C3=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H12 mock treatment 2520.0 -7.32 0.0 2840.0 -226.0 -0.1 -0.0758 -0.7282 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H13 compound treatment 2040.0 -487.0 -0.21 2400.0 -666.0 -0.31 -0.3648 -0.9829 429 Bio2_000876 NCCc1c[nH]c2ccc(O)cc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H14 mock treatment 2480.0 -47.3 -0.02 2320.0 -746.0 -0.34 -0.257 -0.7477 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H15 compound treatment 2680.0 153.0 0.07 2400.0 -666.0 -0.31 -0.1702 -0.5432 2269 Bio2_000877 Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H16 mock treatment 2640.0 113.0 0.05 2800.0 -266.0 -0.12 -0.0523 -0.3972 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H17 compound treatment 2800.0 273.0 0.12 3000.0 -66.3 -0.03 0.0614 0.5066 2301 Bio2_000878 O=C1CCc2c(O1)ccc3ccccc23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H18 mock treatment 2400.0 -127.0 -0.05 2640.0 -426.0 -0.2 -0.1773 -0.8713 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H19 compound treatment 3400.0 873.0 0.38 3960.0 894.0 0.41 0.556 0.999 650 Bio2_000879 CC(C)(C)n1nc(c2ccc(Cl)cc2)c3c(N)ncnc13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H20 mock treatment 2680.0 153.0 0.07 3480.0 414.0 0.19 0.181 0.8991 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H21 compound treatment 2840.0 313.0 0.13 3760.0 694.0 0.32 0.3207 0.9263 648 Bio2_000880 Oc1cc(O)cc(/C=C/c2ccc(O)c(O)c2)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H22 mock treatment 3000.0 473.0 0.2 3160.0 93.8 0.04 0.1742 0.8384 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H23 mock treatment 2560.0 32.7 0.01 3840.0 774.0 0.36 0.2615 0.7345 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 H24 mock treatment 120.0 -2410.0 -1.04 160.0 -2910.0 -1.34 -1.677 -0.992 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I01 mock treatment 2280.0 -247.0 -0.11 3240.0 174.0 0.08 -0.0187 -0.1407 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I02 mock treatment 3160.0 633.0 0.27 3760.0 694.0 0.32 0.418 0.9969 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I03 compound treatment 1400.0 -1130.0 -0.48 2680.0 -386.0 -0.18 -0.4684 -0.9072 369 Bio2_000881 CCOc1ccc(cc1)c2nc3cc(ccc3[nH]2)c4nc5cc(ccc5[nH]4)N6CCN(C)CC6 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I04 mock treatment 2680.0 153.0 0.07 3520.0 454.0 0.21 0.194 0.8868 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I05 compound treatment 2680.0 153.0 0.07 3240.0 174.0 0.08 0.1029 0.9953 1001953 Bio2_000882 C/C=C/1\C2Cc3[nH]c(=O)ccc3C1(N)CC(=C2)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I06 mock treatment 2600.0 72.7 0.03 3400.0 334.0 0.15 0.1306 0.834 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I07 compound treatment 2480.0 -47.3 -0.02 2800.0 -266.0 -0.12 -0.101 -0.8135 1907776 Bio2_000883 CC(C)[C@H](O)CCC(C)C1CCC2C3CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@]12C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I08 mock treatment 1920.0 -607.0 -0.26 3040.0 -26.3 -0.01 -0.1932 -0.739 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I09 compound treatment 2240.0 -287.0 -0.12 2480.0 -586.0 -0.27 -0.278 -0.9374 3002553 Bio2_000884 C[C@@H]([C@@H](C)N1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I10 mock treatment 1680.0 -847.0 -0.36 2680.0 -386.0 -0.18 -0.3833 -0.9454 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I11 compound treatment 2360.0 -167.0 -0.07 2120.0 -946.0 -0.44 -0.3585 -0.813 2797 Bio2_000885 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)O)c2c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I12 mock treatment 2400.0 -127.0 -0.05 2120.0 -946.0 -0.44 -0.3464 -0.7899 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I13 compound treatment 1240.0 -1290.0 -0.55 680.0 -2390.0 -1.1 -1.1673 -0.9498 3002555 Bio2_000886 *CC[C@@H](C)C[C@H](C)C[C@H](C)C(=O)/C=C(\O)/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)C[C@@H]1CC[C@](C)(O1)[C@H]2CC[C@](C)(O2)[C@@H](C)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I14 mock treatment 2320.0 -207.0 -0.09 2720.0 -346.0 -0.16 -0.1756 -0.9625 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I15 compound treatment 2280.0 -247.0 -0.11 2280.0 -786.0 -0.36 -0.3309 -0.8779 1505 Bio2_000887 CC(C)Cn1c(=O)n(C)c(=O)c2[nH]cnc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I16 mock treatment 2280.0 -247.0 -0.11 2800.0 -266.0 -0.12 -0.1618 -0.9975 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I17 compound treatment 80.0 -2450.0 -1.05 120.0 -2950.0 -1.35 -1.7022 -0.9922 1054783 Bio2_000888 OCCSC1=C(SCCO)C(=O)c2ccccc2C1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I18 mock treatment 3160.0 633.0 0.27 2400.0 -666.0 -0.31 -0.0242 -0.0591 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I19 compound treatment 1280.0 -1250.0 -0.54 1640.0 -1430.0 -0.66 -0.843 -0.995 422 Bio2_000889 Oc1cccc2C(=O)C=CC(=O)c12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I20 mock treatment 2680.0 153.0 0.07 3280.0 214.0 0.1 0.1159 0.9808 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I21 compound treatment 3600.0 1070.0 0.46 4280.0 1210.0 0.56 0.7208 0.9955 1907777 Bio2_000890 COC(=O)[C@@]1(O)C[C@@H]2O[C@@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I22 mock treatment 2920.0 393.0 0.17 3840.0 774.0 0.36 0.371 0.942 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I23 mock treatment 3040.0 513.0 0.22 3440.0 374.0 0.17 0.2774 0.9924 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 I24 mock treatment 120.0 -2410.0 -1.04 160.0 -2910.0 -1.34 -1.677 -0.992 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J01 mock treatment 3400.0 873.0 0.38 3400.0 334.0 0.15 0.3739 0.9221 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J02 mock treatment 3440.0 913.0 0.39 3720.0 654.0 0.3 0.4901 0.9913 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J03 compound treatment 2560.0 32.7 0.01 3040.0 -26.3 -0.01 0.0014 0.0757 837968 Bio2_000891 Nc1ncnc2n(cnc12)C3CCCO3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J04 mock treatment 1840.0 -687.0 -0.3 3120.0 53.8 0.02 -0.1915 -0.6457 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J05 compound treatment 2960.0 433.0 0.19 3360.0 294.0 0.14 0.2271 0.9876 790507 Bio2_000892 OC(=O)CN1C(=O)c2cccc3cccc(C1=O)c23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J06 mock treatment 2480.0 -47.3 -0.02 5680.0 2610.0 1.2 0.8354 0.695 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J07 compound treatment 80.0 -2450.0 -1.05 200.0 -2870.0 -1.32 -1.6762 -0.9938 3104896 Bio2_000893 CN[C@@H]1C[C@@]2(C)O[C@@H]([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J08 mock treatment 2280.0 -247.0 -0.11 2880.0 -186.0 -0.09 -0.1358 -0.9942 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J09 compound treatment 2880.0 353.0 0.15 2920.0 -146.0 -0.07 0.0597 0.3598 197 Bio2_000894 O[C@@H]1CN2CCC[C@@H](O)[C@@H]2[C@@H]1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J10 mock treatment 1960.0 -567.0 -0.24 2400.0 -666.0 -0.31 -0.3891 -0.9936 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J11 compound treatment 2040.0 -487.0 -0.21 2280.0 -786.0 -0.36 -0.4038 -0.9664 368 Bio2_000895 CC/C(=C(\c1ccccc1)/c2ccc(OCCN(C)C)cc2)/c3ccccc3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J12 mock treatment 2520.0 -7.32 0.0 2640.0 -426.0 -0.2 -0.1408 -0.7184 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J13 compound treatment 2400.0 -127.0 -0.05 2720.0 -346.0 -0.16 -0.1513 -0.8986 1000045 Bio2_000896 CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c3ccccc3)C4[C@@]5(CO[C@@H]5C[C@H](O)[C@@]4(C)C1=O)OC(=O)C)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c6ccccc6)c7ccccc7 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J14 mock treatment 2200.0 -327.0 -0.14 2240.0 -826.0 -0.38 -0.3682 -0.9087 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J15 compound treatment 3000.0 473.0 0.2 2440.0 -626.0 -0.29 -0.0599 -0.1699 658 Bio2_000897 Clc1cc(Cl)cc(/C=C(\C#N)/c2cccnc2)c1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J16 mock treatment 2480.0 -47.3 -0.02 2800.0 -266.0 -0.12 -0.101 -0.8135 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J17 compound treatment 2880.0 353.0 0.15 2720.0 -346.0 -0.16 -0.0053 -0.0242 370 Bio2_000898 O=C1N(C2CCC(=O)NC2=O)C(=O)c3ccccc13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J18 mock treatment 2760.0 233.0 0.1 2920.0 -146.0 -0.07 0.0232 0.1925 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J19 compound treatment 2360.0 -167.0 -0.07 2920.0 -146.0 -0.07 -0.0984 -0.9994 358 Bio2_000899 N[C@@H](CCCNC(=S)N)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J20 mock treatment 2480.0 -47.3 -0.02 2960.0 -106.0 -0.05 -0.0489 -0.9246 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J21 compound treatment 2960.0 433.0 0.19 4600.0 1530.0 0.71 0.6303 0.8641 572 Bio2_000900 CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c3c[nH]c4ccccc34)c5ccccc15 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J22 mock treatment 2680.0 153.0 0.07 3840.0 774.0 0.36 0.298 0.8237 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J23 mock treatment 2960.0 433.0 0.19 2920.0 -146.0 -0.07 0.084 0.4247 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 J24 mock treatment 120.0 -2410.0 -1.04 160.0 -2910.0 -1.34 -1.677 -0.992 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K01 mock treatment 3120.0 593.0 0.25 4400.0 1330.0 0.61 0.6139 0.9243 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K02 mock treatment 3080.0 553.0 0.24 3120.0 53.8 0.02 0.1855 0.7764 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K03 compound treatment 1920.0 -607.0 -0.26 2360.0 -706.0 -0.32 -0.4143 -0.9942 3419827 Bio2_000901 CN(C(Cc1ccc(OS(=O)(=O)c2cccc3cnccc23)cc1)C(=O)N4CCN(CC4)c5ccccc5)S(=O)(=O)c6cccc7cnccc67 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K04 mock treatment 2160.0 -367.0 -0.16 2960.0 -106.0 -0.05 -0.1463 -0.8845 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K05 compound treatment 2440.0 -87.3 -0.04 2920.0 -146.0 -0.07 -0.0741 -0.9621 1907778 Bio2_000902 *[C@@]1(O)C[C@@H]2O[C@@]1(C)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K06 mock treatment 1760.0 -767.0 -0.33 3040.0 -26.3 -0.01 -0.2419 -0.7325 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K07 compound treatment 2480.0 -47.3 -0.02 2960.0 -106.0 -0.05 -0.0489 -0.9246 3104897 Bio2_000903 CCC(C)[C@@H](CO[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCS(=O)(=O)C)C(=O)OC(C)C)NC[C@@H](N)CS 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K08 mock treatment 2320.0 -207.0 -0.09 3240.0 174.0 0.08 -0.0066 -0.0548 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K09 compound treatment 920.0 -1610.0 -0.69 1440.0 -1630.0 -0.75 -1.0175 -0.9992 1908 Bio2_000904 [O-][n+]1onc(c1C#N)c2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K10 mock treatment 2280.0 -247.0 -0.11 2920.0 -146.0 -0.07 -0.1228 -0.9755 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K11 compound treatment 2280.0 -247.0 -0.11 2280.0 -786.0 -0.36 -0.3309 -0.8779 3001166 Bio2_000905 C[C@H]/1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]3CSC(=O)N3)OC(=O)\C=C(\C)/CC/C=C1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K12 mock treatment 2080.0 -447.0 -0.19 2120.0 -946.0 -0.44 -0.4437 -0.9327 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K13 compound treatment 2160.0 -367.0 -0.16 2360.0 -706.0 -0.32 -0.3413 -0.9452 284 Bio2_000906 OC(=O)c1cc(ccc1O)N(Cc2ccccc2O)Cc3cc(O)ccc3O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K14 mock treatment 1920.0 -607.0 -0.26 2360.0 -706.0 -0.32 -0.4143 -0.9942 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K15 compound treatment 2040.0 -487.0 -0.21 2280.0 -786.0 -0.36 -0.4038 -0.9664 1907779 Bio2_000907 CC(C)n1cnc2c(NCc3ccccc3)nc(NCCO)nc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K16 mock treatment 2200.0 -327.0 -0.14 2600.0 -466.0 -0.21 -0.2511 -0.9792 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K17 compound treatment 2320.0 -207.0 -0.09 2160.0 -906.0 -0.42 -0.3577 -0.8394 3104898 Bio2_000908 CC(C)C[C@H](NC(=O)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K18 mock treatment 2080.0 -447.0 -0.19 2280.0 -786.0 -0.36 -0.3917 -0.9564 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K19 compound treatment 120.0 -2410.0 -1.04 240.0 -2830.0 -1.3 -1.651 -0.9937 1954 Bio2_000909 Cc1ccc(cc1)S(=O)(=O)/C=C/C#N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K20 mock treatment 2640.0 113.0 0.05 3120.0 53.8 0.02 0.0517 0.9512 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K21 compound treatment 2160.0 -367.0 -0.16 2400.0 -666.0 -0.31 -0.3283 -0.9525 1002387 Bio2_000910 Oc1ccc(C=C(C#N)C#N)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K22 mock treatment 2080.0 -447.0 -0.19 2960.0 -106.0 -0.05 -0.1706 -0.8594 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K23 mock treatment 2720.0 193.0 0.08 3320.0 254.0 0.12 0.1411 0.9859 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 K24 mock treatment 120.0 -2410.0 -1.04 200.0 -2870.0 -1.32 -1.664 -0.9929 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L01 mock treatment 4800.0 2270.0 0.98 3720.0 654.0 0.3 0.9037 0.8837 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L02 mock treatment 4160.0 1630.0 0.7 3520.0 454.0 0.21 0.644 0.8792 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L03 compound treatment 4840.0 2310.0 0.99 3720.0 654.0 0.3 0.9159 0.8814 566 Bio2_000911 COc1cc(/C=C(\C#N)/C(=O)N)cc(CSc2nc3ccccc3s2)c1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L04 mock treatment 3040.0 513.0 0.22 3040.0 -26.3 -0.01 0.1474 0.6674 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L05 compound treatment 3000.0 473.0 0.2 3280.0 214.0 0.1 0.2132 0.9444 1907780 Bio2_000912 COC1=CC(=O)OC(C1)/C=C/c2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L06 mock treatment 2320.0 -207.0 -0.09 3080.0 13.8 0.01 -0.0586 -0.6553 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L07 compound treatment 2520.0 -7.32 0.0 2560.0 -506.0 -0.23 -0.1668 -0.7166 431 Bio2_000913 C(CN(Cc1ccccn1)Cc2ccccn2)N(Cc3ccccn3)Cc4ccccn4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L08 mock treatment 2920.0 393.0 0.17 4040.0 974.0 0.45 0.436 0.9112 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L09 compound treatment 2440.0 -87.3 -0.04 3400.0 334.0 0.15 0.082 0.5188 199 Bio2_000914 C[C@H](/C=C(\C)/C=C/C(=O)NO)C(=O)c1ccc(cc1)N(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L10 mock treatment 2600.0 72.7 0.03 3080.0 13.8 0.01 0.0266 0.8333 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L11 compound treatment 2000.0 -527.0 -0.23 2480.0 -586.0 -0.27 -0.351 -0.9963 437 Bio2_000915 CN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L12 mock treatment 2160.0 -367.0 -0.16 3040.0 -26.3 -0.01 -0.1202 -0.7589 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L13 compound treatment 1960.0 -567.0 -0.24 2520.0 -546.0 -0.25 -0.3501 -0.9999 3001422 Bio2_000916 *C1OC(OC2OC(CC(O)C3OC(C(O)C3O)n4ccc(=O)[nH]c4=O)C(O)C(O)C2NC(=O)/C=C\*C(C)C)C(NC(=O)C)C(O)C1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L14 mock treatment 2120.0 -407.0 -0.18 2800.0 -266.0 -0.12 -0.2104 -0.9847 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L15 compound treatment 2320.0 -207.0 -0.09 2120.0 -946.0 -0.44 -0.3707 -0.8347 203 Bio2_000917 NC(=C(C#N)C#N)/C(=C/c1ccc2[nH]ccc2c1)/C#N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L16 mock treatment 2360.0 -167.0 -0.07 2360.0 -706.0 -0.32 -0.2805 -0.8433 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L17 compound treatment 1560.0 -967.0 -0.42 2120.0 -946.0 -0.44 -0.6018 -0.9997 553 Bio2_000918 Oc1cc(C=C(C#N)C#N)ccc1[N+](=O)[O-] 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L18 mock treatment 2280.0 -247.0 -0.11 2200.0 -866.0 -0.4 -0.3569 -0.8656 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L19 compound treatment 2280.0 -247.0 -0.11 2000.0 -1070.0 -0.49 -0.4219 -0.841 568 Bio2_000919 COc1ccc(C=C(C#N)C#N)cc1 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L20 mock treatment 2120.0 -407.0 -0.18 2920.0 -146.0 -0.07 -0.1714 -0.9136 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L21 compound treatment 120.0 -2410.0 -1.04 240.0 -2830.0 -1.3 -1.651 -0.9937 5 Bio2_000920 CC(C)(C)c1cc(C=C(C#N)C#N)cc(c1O)C(C)(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L22 mock treatment 2840.0 313.0 0.13 3040.0 -26.3 -0.01 0.0866 0.6411 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L23 mock treatment 3240.0 713.0 0.31 4440.0 1370.0 0.63 0.6634 0.9449 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 L24 mock treatment 160.0 -2370.0 -1.02 120.0 -2950.0 -1.35 -1.6779 -0.9901 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M01 mock treatment 3040.0 513.0 0.22 3080.0 13.8 0.01 0.1604 0.7271 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M02 mock treatment 3200.0 673.0 0.29 3640.0 574.0 0.26 0.3911 0.9989 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M03 compound treatment 2760.0 233.0 0.1 3880.0 814.0 0.37 0.3353 0.8658 423 Bio2_000921 COC(=O)[C@@H](N)CCCNC(=N)N[N+](=O)[O-] 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M04 mock treatment 2560.0 32.7 0.01 2600.0 -466.0 -0.21 -0.1417 -0.6593 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M05 compound treatment 1760.0 -767.0 -0.33 2280.0 -786.0 -0.36 -0.489 -0.999 321 Bio2_000922 O=c1cc(oc2c(cccc12)c3ccccc3)N4CCOCC4 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M06 mock treatment 2800.0 273.0 0.12 3360.0 294.0 0.14 0.1784 0.9975 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M07 compound treatment 560.0 -1970.0 -0.85 1000.0 -2070.0 -0.95 -1.2701 -0.9983 243 Bio2_000923 O=C1C=C(Nc2ccccc2)C(=O)c3cccnc13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M08 mock treatment 2440.0 -87.3 -0.04 3200.0 134.0 0.06 0.0169 0.235 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M09 compound treatment 80.0 -2450.0 -1.05 200.0 -2870.0 -1.32 -1.6762 -0.9938 1059329 Bio2_000924 Nc1ncnc2n(cc(I)c12)C3OC(CO)C(O)C3O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M10 mock treatment 2200.0 -327.0 -0.14 2640.0 -426.0 -0.2 -0.2381 -0.9868 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M11 compound treatment 1440.0 -1090.0 -0.47 1960.0 -1110.0 -0.51 -0.6903 -0.9991 3104900 Bio2_000925 C/C(=C\CCC1C=CC(OC1O)C2=CC(=O)OC2O)/CCC3=C(C)CCCC3(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M12 mock treatment 2520.0 -7.32 0.0 2360.0 -706.0 -0.32 -0.2319 -0.7139 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M13 compound treatment 1800.0 -727.0 -0.31 2680.0 -386.0 -0.18 -0.3468 -0.964 192 Bio2_000926 CCCCC(C)/C=C(\C)/C=C(\C)/C(=O)NC1=CC(O)(\C=C\C=C\C=C\C(=O)NC2=C(O)CCC2=O)C3OC3C1=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M14 mock treatment 1960.0 -567.0 -0.24 2800.0 -266.0 -0.12 -0.2591 -0.9491 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M15 compound treatment 2720.0 193.0 0.08 2320.0 -746.0 -0.34 -0.184 -0.5214 907409 Bio2_000927 CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M16 mock treatment 1840.0 -687.0 -0.3 2600.0 -466.0 -0.21 -0.3606 -0.9876 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M17 compound treatment 2600.0 72.7 0.03 2360.0 -706.0 -0.32 -0.2075 -0.6361 419 Bio2_000928 CC1=NN(C(=O)C1)c2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M18 mock treatment 2280.0 -247.0 -0.11 2040.0 -1030.0 -0.47 -0.4089 -0.8453 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M19 compound treatment 80.0 -2450.0 -1.05 120.0 -2950.0 -1.35 -1.7022 -0.9922 3002144 Bio2_000929 CN1C(=O)[C@@]23CC4=CC=C[C@H](O)[C@H]4N3C(=O)[C@@]1(CO)[S+](C)S2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M20 mock treatment 2960.0 433.0 0.19 2840.0 -226.0 -0.1 0.058 0.2721 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M21 compound treatment 2520.0 -7.32 0.0 3400.0 334.0 0.15 0.1063 0.6925 638 Bio2_000930 C/C(=C(\C#N)/C(=O)Nc1cc(Br)ccc1Br)/O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M22 mock treatment 3120.0 593.0 0.25 3560.0 494.0 0.23 0.3408 0.9983 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M23 mock treatment 2560.0 32.7 0.01 3560.0 494.0 0.23 0.1705 0.7494 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 M24 mock treatment 120.0 -2410.0 -1.04 160.0 -2910.0 -1.34 -1.677 -0.992 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N01 mock treatment 3760.0 1230.0 0.53 3400.0 334.0 0.15 0.4834 0.8758 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N02 mock treatment 3720.0 1190.0 0.51 4240.0 1170.0 0.54 0.7443 0.9997 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N03 compound treatment 3920.0 1390.0 0.6 4720.0 1650.0 0.76 0.9612 0.993 3104901 Bio2_000931 CCCc1cc(OC)ccc1C.CC12CCCCC2CCC1NCCCCCCN3C(=O)C=CC3=O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N04 mock treatment 3160.0 633.0 0.27 2880.0 -186.0 -0.09 0.1318 0.4622 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N05 compound treatment 1520.0 -1010.0 -0.43 2520.0 -546.0 -0.25 -0.4839 -0.9664 325 Bio2_000932 N/C(=C(/C#N)\C(=C(/N)\Sc1ccccc1N)\C#N)/Sc2ccccc2N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N06 mock treatment 2520.0 -7.32 0.0 3000.0 -66.3 -0.03 -0.0238 -0.7761 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N07 compound treatment 120.0 -2410.0 -1.04 160.0 -2910.0 -1.34 -1.677 -0.992 2430 Bio2_000933 CC(C)C1NC(=O)C(C)OC(=O)C(NC(=O)C(OC(=O)C(NC(=O)C(C)OC(=O)C(NC(=O)C(OC(=O)C(NC(=O)C(C)OC(=O)C(NC(=O)C(OC1=O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N08 mock treatment 2520.0 -7.32 0.0 2440.0 -626.0 -0.29 -0.2058 -0.7148 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N09 compound treatment 4240.0 1710.0 0.74 6160.0 3090.0 1.42 1.5267 0.9531 3002149 Bio2_000934 *[C@@H]1[C@H]([C@@H]2CN(C[C@](O)(CC)C2)CCc3c1[nH]c4ccccc34)c5cc6c(cc5OC)N(C)[C@@H]7[C@@]86CCN9CC=C[C@](CC)([C@H]98)[C@@H](O)[C@]7(O)C(=O)OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N10 mock treatment 2400.0 -127.0 -0.05 2640.0 -426.0 -0.2 -0.1773 -0.8713 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N11 compound treatment 2080.0 -447.0 -0.19 2800.0 -266.0 -0.12 -0.2226 -0.9762 3002210 Bio2_000935 *CCCCCCNOc1cccc2c(Cl)cccc12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N12 mock treatment 2520.0 -7.32 0.0 3240.0 174.0 0.08 0.0543 0.6787 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N13 compound treatment 4360.0 1830.0 0.79 3480.0 414.0 0.19 0.6919 0.8533 293 Bio2_000936 COC[C@H]1OC(=O)c2coc3C(=O)C4=C([C@@H](C[C@@]5(C)C4CCC5=O)OC(=O)C)[C@]1(C)c23 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N14 mock treatment 2200.0 -327.0 -0.14 2800.0 -266.0 -0.12 -0.1861 -0.9976 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N15 compound treatment 2400.0 -127.0 -0.05 2440.0 -626.0 -0.29 -0.2423 -0.8268 677 Bio2_000937 C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc2ccncc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N16 mock treatment 2600.0 72.7 0.03 2360.0 -706.0 -0.32 -0.2075 -0.6361 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N17 compound treatment 2000.0 -527.0 -0.23 2720.0 -346.0 -0.16 -0.2729 -0.985 3000363 Bio2_000938 COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N18 mock treatment 2800.0 273.0 0.12 2840.0 -226.0 -0.1 0.0094 0.0597 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N19 compound treatment 2000.0 -527.0 -0.23 2400.0 -666.0 -0.31 -0.377 -0.989 207 Bio2_000939 CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)/C=C/S(=O)(=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N20 mock treatment 2160.0 -367.0 -0.16 2800.0 -266.0 -0.12 -0.1983 -0.9921 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N21 compound treatment 2480.0 -47.3 -0.02 3480.0 414.0 0.19 0.1201 0.6279 352 Bio2_000940 CN(C)c1cccc(c1)C(=O)Nc2ccc(C)c(NC(=O)c3ccc(O)cc3)c2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N22 mock treatment 2720.0 193.0 0.08 3840.0 774.0 0.36 0.3102 0.8491 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N23 mock treatment 3360.0 833.0 0.36 3280.0 214.0 0.1 0.3227 0.869 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 N24 mock treatment 120.0 -2410.0 -1.04 200.0 -2870.0 -1.32 -1.664 -0.9929 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O01 mock treatment 3600.0 1070.0 0.46 4480.0 1410.0 0.65 0.7859 0.9859 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O02 mock treatment 2840.0 313.0 0.13 4080.0 1010.0 0.47 0.4247 0.8754 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O03 compound treatment 3640.0 1110.0 0.48 3800.0 734.0 0.34 0.5769 0.9854 3002219 Bio2_000941 *CCC(NC(=O)c1ccc(cc1)N(C)Cc2cnc3nc(N)nc(N)c3n2)C(=O)O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O04 mock treatment 2880.0 353.0 0.15 3240.0 174.0 0.08 0.1637 0.9552 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O05 compound treatment 2880.0 353.0 0.15 2880.0 -186.0 -0.09 0.0467 0.2681 1001921 Bio2_000942 Clc1ccc(cn1)C2CC3CCC2N3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O06 mock treatment 2640.0 113.0 0.05 2800.0 -266.0 -0.12 -0.0523 -0.3972 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O07 compound treatment 2280.0 -247.0 -0.11 3080.0 13.8 0.01 -0.0707 -0.6639 381 Bio2_000943 CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3CCCC(=O)O3)[C@@H]12 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O08 mock treatment 2360.0 -167.0 -0.07 3000.0 -66.3 -0.03 -0.0724 -0.9268 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O09 compound treatment 2520.0 -7.32 0.0 2920.0 -146.0 -0.07 -0.0498 -0.7394 1000019 Bio2_000944 CO[C@@]12[C@H]3N[C@H]3CN2C4=C([C@H]1COC(=O)N)C(=O)C(=C(C)C4=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O10 mock treatment 2960.0 433.0 0.19 3160.0 93.8 0.04 0.1621 0.8484 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O11 compound treatment 2320.0 -207.0 -0.09 3040.0 -26.3 -0.01 -0.0716 -0.7956 281 Bio2_000945 Ic1cccc2c(cccc12)S(=O)(=O)N3CCCNCC3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O12 mock treatment 2720.0 193.0 0.08 2960.0 -106.0 -0.05 0.024 0.25 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O13 compound treatment 2120.0 -407.0 -0.18 2280.0 -786.0 -0.36 -0.3795 -0.9447 3002225 Bio2_000946 Clc1cccc2c(cccc12)S(=O)(=O)N3CC*CCC3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O14 mock treatment 2640.0 113.0 0.05 2920.0 -146.0 -0.07 -0.0133 -0.1603 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O15 compound treatment 2160.0 -367.0 -0.16 2520.0 -546.0 -0.25 -0.2893 -0.975 438 Bio2_000947 CCOC(=O)C1=C(C)NC(=S)NC1c2cccc(O)c2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O16 mock treatment 2600.0 72.7 0.03 2400.0 -666.0 -0.31 -0.1945 -0.6317 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O17 compound treatment 2360.0 -167.0 -0.07 2240.0 -826.0 -0.38 -0.3195 -0.8263 656 Bio2_000948 Oc1c(Br)cc(/C=C/2\C(=O)Nc3ccc(I)cc23)cc1Br 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O18 mock treatment 2560.0 32.7 0.01 2520.0 -546.0 -0.25 -0.1677 -0.6665 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O19 compound treatment 1360.0 -1170.0 -0.5 1760.0 -1310.0 -0.6 -0.7797 -0.996 3104902 Bio2_000949 CC[C@]1(CC[C@@H](O1)[C@]2(C)CC[C@]3(C[C@H](O)[C@@H](C)[C@H](O3)[C@@H](C)C/C=C(\C)/OO)O2)[C@@H]4O[C@H](C[C@@H]4C)[C@H]5O[C@@](O)(CO)[C@H](C)C[C@@H]5C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O20 mock treatment 2840.0 313.0 0.13 2480.0 -586.0 -0.27 -0.0955 -0.3171 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O21 compound treatment 2200.0 -327.0 -0.14 2520.0 -546.0 -0.25 -0.2771 -0.9625 1907781 Bio2_000950 CO[C@@H]1C[C@@H](CC[C@H]1O)/C=C(\C)/[C@H]2OC(=O)C3CCCCN3C(=O)C(=O)[C@]4(O)O[C@@H]([C@H](C[C@H]4C)OC)[C@H](C[C@@H](C)C\C(=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)\C)OC 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O22 mock treatment 2480.0 -47.3 -0.02 3440.0 374.0 0.17 0.1071 0.619 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O23 mock treatment 2880.0 353.0 0.15 3200.0 134.0 0.06 0.1507 0.921 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 O24 mock treatment 160.0 -2370.0 -1.02 200.0 -2870.0 -1.32 -1.6518 -0.9919 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P01 mock treatment 4360.0 1830.0 0.79 4360.0 1290.0 0.59 0.978 0.9904 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P02 mock treatment 3080.0 553.0 0.24 3760.0 694.0 0.32 0.3936 0.9895 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P03 compound treatment 3320.0 793.0 0.34 4320.0 1250.0 0.58 0.6487 0.9686 201 Bio2_000951 COC(=O)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)CF 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P04 mock treatment 3360.0 833.0 0.36 3680.0 614.0 0.28 0.4528 0.993 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P05 compound treatment 3480.0 953.0 0.41 4280.0 1210.0 0.56 0.6844 0.9885 2217 Bio2_000952 CS(=O)(=O)Nc1ccc(cc1OC2CCCCC2)[N+](=O)[O-] 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P06 mock treatment 2920.0 393.0 0.17 3080.0 13.8 0.01 0.1239 0.7331 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P07 compound treatment 1960.0 -567.0 -0.24 2720.0 -346.0 -0.16 -0.2851 -0.9786 1917 Bio2_000953 CC1=C(C)C(=O)C(=C(C)C1=O)CCCCC#CCCCC#CCO 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P08 mock treatment 2760.0 233.0 0.1 2200.0 -866.0 -0.4 -0.2109 -0.5135 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P09 compound treatment 2560.0 32.7 0.01 3080.0 13.8 0.01 0.0144 0.935 3002232 Bio2_000954 *CC/C(=C/Cc1c(O)c2C(=O)OCc2c(C)c1OC)/C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P10 mock treatment 2680.0 153.0 0.07 3120.0 53.8 0.02 0.0639 0.9109 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P11 compound treatment 2520.0 -7.32 0.0 2680.0 -386.0 -0.18 -0.1278 -0.7195 2288 Bio2_000955 CC(=CCC(O)C1=CC(=O)c2c(O)ccc(O)c2C1=O)C 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P12 mock treatment 2480.0 -47.3 -0.02 2760.0 -306.0 -0.14 -0.114 -0.801 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P13 compound treatment 2600.0 72.7 0.03 3200.0 134.0 0.06 0.0656 0.9507 3104904 Bio2_000956 C1C[C@H]2CCCCCC[C@H]3CCN4CCC[C@H](CCCCCC[C@H]5CCN(C1)[C@@H]2O5)[C@H]4O3 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P14 mock treatment 2760.0 233.0 0.1 2600.0 -466.0 -0.21 -0.0808 -0.3417 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P15 compound treatment 2560.0 32.7 0.01 2640.0 -426.0 -0.2 -0.1287 -0.6547 1907782 Bio2_000957 Oc1ccc(/C=C(/C#N)\C(=O)OC\C=C\c2ccccc2)cc1O 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P16 mock treatment 2600.0 72.7 0.03 3000.0 -66.3 -0.03 6.0E-4 0.0129 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P17 compound treatment 1000.0 -1530.0 -0.66 1520.0 -1550.0 -0.71 -0.9672 -0.9992 3104917 Bio2_000958 C/C=C/C\C=C\CCC(=O)[C@H]1O[C@H]1C(=O)N 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P18 mock treatment 2200.0 -327.0 -0.14 2680.0 -386.0 -0.18 -0.2251 -0.9934 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P19 compound treatment 1880.0 -647.0 -0.28 2400.0 -666.0 -0.31 -0.4135 -0.9989 1395 Bio2_000959 CC(COc1ccccc1)N(CCCl)Cc2ccccc2 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P20 mock treatment 2280.0 -247.0 -0.11 3200.0 134.0 0.06 -0.0317 -0.2582 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P21 compound treatment 1960.0 -567.0 -0.24 3400.0 334.0 0.15 -0.064 -0.2221 1303231 Bio2_000960 CN(C)CC(O)Cn1c2ccc(Br)cc2c3cc(Br)ccc13 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P22 mock treatment 2600.0 72.7 0.03 3400.0 334.0 0.15 0.1306 0.834 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P23 mock treatment 2520.0 -7.32 0.0 3000.0 -66.3 -0.03 -0.0238 -0.7761 1009.0001 LuxReporter(1009.0001) cAMPSignalingReporter 1009.0001.2129 P24 mock treatment 200.0 -2330.0 -1.0 160.0 -2910.0 -1.34 -1.6527 -0.9899