ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES RAW_VALUE_C BSUB_VALUE_C Z_SCORE_C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A01 compound treatment 209920.0 -462000.0 -1.24 182730.0 -446000.0 -1.22 -1.7384 -1.0 3186889 PK04_093001 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A02 compound treatment 284660.0 -388000.0 -1.04 238960.0 -389000.0 -1.07 -1.4881 -0.9999 3067555 PK04_093002 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A03 compound treatment 207090.0 -465000.0 -1.24 195100.0 -433000.0 -1.19 -1.7198 -0.9998 3186890 PK04_093003 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A04 compound treatment 224360.0 -448000.0 -1.2 334330.0 -294000.0 -0.81 -1.4168 -0.9816 3186891 PK04_093004 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A05 compound treatment 259950.0 -412000.0 -1.1 221120.0 -407000.0 -1.12 -1.5694 -1.0 3067558 PK04_093005 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A06 compound treatment 278080.0 -394000.0 -1.05 151680.0 -477000.0 -1.31 -1.67 -0.9942 3186892 PK04_093006 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A07 compound treatment 236370.0 -436000.0 -1.16 400970.0 -227000.0 -0.62 -1.2648 -0.9573 3067559 PK04_093007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A08 compound treatment 261600.0 -411000.0 -1.1 233200.0 -395000.0 -1.08 -1.5428 -1.0 3186893 PK04_093008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A09 compound treatment 356180.0 -316000.0 -0.84 529440.0 -98900.0 -0.27 -0.7891 -0.8896 3186894 PK04_093009 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A10 compound treatment 264960.0 -407000.0 -1.09 236400.0 -392000.0 -1.08 -1.5303 -1.0 3067560 PK04_093010 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A11 compound treatment 265250.0 -407000.0 -1.09 328930.0 -299000.0 -0.82 -1.3501 -0.9905 3186895 PK04_093011 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A12 compound treatment 194420.0 -478000.0 -1.28 236550.0 -392000.0 -1.08 -1.6632 -0.9964 3186896 PK04_093012 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A13 mock treatment 627250.0 -45100.0 -0.12 291620.0 -337000.0 -0.92 -0.7388 -0.7925 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A14 mock treatment 348640.0 -324000.0 -0.86 300910.0 -327000.0 -0.9 -1.247 -0.9998 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A15 compound treatment 273560.0 -399000.0 -1.07 222310.0 -406000.0 -1.11 -1.5414 -0.9997 3067562 PK04_093013 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A16 compound treatment 279040.0 -393000.0 -1.05 303010.0 -325000.0 -0.89 -1.3744 -0.9967 3186897 PK04_093014 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A17 compound treatment 322560.0 -350000.0 -0.93 614360.0 -14000.0 -0.04 -0.6878 -0.7356 3067564 PK04_093015 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A18 compound treatment 320200.0 -352000.0 -0.94 331200.0 -297000.0 -0.82 -1.2419 -0.9975 3186898 PK04_093016 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A19 compound treatment 190350.0 -482000.0 -1.29 258920.0 -369000.0 -1.01 -1.6275 -0.993 3186899 PK04_093017 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A20 compound treatment 295360.0 -377000.0 -1.01 314470.0 -314000.0 -0.86 -1.3213 -0.997 3067604 PK04_093018 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A21 compound treatment 244970.0 -427000.0 -1.14 551310.0 -77000.0 -0.21 -0.9567 -0.8241 3186900 PK04_093019 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A22 compound treatment 370580.0 -302000.0 -0.81 446590.0 -182000.0 -0.5 -0.9228 -0.9734 3067607 PK04_093020 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A23 compound treatment 704080.0 31700.0 0.08 439850.0 -188000.0 -0.52 -0.306 -0.5835 3186901 PK04_093021 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 A24 compound treatment 587950.0 -84400.0 -0.23 285760.0 -343000.0 -0.94 -0.8244 -0.8524 3186902 PK04_093022 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B01 compound treatment 340230.0 -332000.0 -0.89 486050.0 -142000.0 -0.39 -0.9035 -0.9321 3067612 PK04_093023 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B02 compound treatment 788450.0 116000.0 0.31 521760.0 -107000.0 -0.29 0.0124 0.0291 3186903 PK04_093024 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B03 compound treatment 565640.0 -107000.0 -0.28 358760.0 -270000.0 -0.74 -0.7249 -0.914 3067614 PK04_093025 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B04 compound treatment 751040.0 78700.0 0.21 603320.0 -25000.0 -0.07 0.1001 0.4524 3186904 PK04_093026 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B05 compound treatment 606090.0 -66200.0 -0.18 231240.0 -397000.0 -1.09 -0.896 -0.8112 3186905 PK04_093027 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B06 compound treatment 718080.0 45700.0 0.12 497000.0 -131000.0 -0.36 -0.1686 -0.4428 3068180 PK04_093028 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B07 compound treatment 653410.0 -18900.0 -0.05 179360.0 -449000.0 -1.23 -0.9074 -0.7355 3186906 PK04_093029 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B08 compound treatment 229990.0 -442000.0 -1.18 178210.0 -450000.0 -1.24 -1.7093 -0.9997 3186992 PK04_093030 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B09 compound treatment 503730.0 -169000.0 -0.45 622940.0 -5410.0 -0.01 -0.3289 -0.73 3068181 PK04_093031 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B10 compound treatment 358890.0 -313000.0 -0.84 384710.0 -244000.0 -0.67 -1.065 -0.9938 3186993 PK04_093032 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B11 compound treatment 365570.0 -307000.0 -0.82 237030.0 -391000.0 -1.07 -1.339 -0.9911 3068182 PK04_093033 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B12 compound treatment 637520.0 -34800.0 -0.09 436380.0 -192000.0 -0.53 -0.4384 -0.8192 3186994 PK04_093034 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B13 mock treatment 420640.0 -252000.0 -0.67 266600.0 -362000.0 -0.99 -1.1776 -0.9819 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B14 mock treatment 827380.0 155000.0 0.41 504030.0 -124000.0 -0.34 0.0515 0.096 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B15 compound treatment 689340.0 17000.0 0.05 418560.0 -210000.0 -0.58 -0.3751 -0.6493 3068183 PK04_093035 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B16 compound treatment 637170.0 -35200.0 -0.09 263150.0 -365000.0 -1.0 -0.7754 -0.77 3186995 PK04_093036 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B17 compound treatment 232080.0 -440000.0 -1.18 248990.0 -379000.0 -1.04 -1.5679 -0.9982 3186996 PK04_093037 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B18 compound treatment 548640.0 -124000.0 -0.33 446400.0 -182000.0 -0.5 -0.5868 -0.9799 3068184 PK04_093038 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B19 compound treatment 284100.0 -388000.0 -1.04 471450.0 -157000.0 -0.43 -1.0378 -0.9243 3186997 PK04_093039 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B20 compound treatment 482930.0 -189000.0 -0.51 359790.0 -269000.0 -0.74 -0.8791 -0.9831 3186998 PK04_093040 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B21 compound treatment 704920.0 32600.0 0.09 345940.0 -282000.0 -0.78 -0.4867 -0.6238 3068185 PK04_093041 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B22 compound treatment 639090.0 -33200.0 -0.09 365200.0 -263000.0 -0.72 -0.5736 -0.7881 3186999 PK04_093042 CN(C)C(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B23 compound treatment 527170.0 -145000.0 -0.39 348160.0 -280000.0 -0.77 -0.8181 -0.9497 3068186 PK04_093043 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 B24 compound treatment 347560.0 -325000.0 -0.87 487150.0 -141000.0 -0.39 -0.8875 -0.9341 3187000 PK04_093044 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C01 compound treatment 153470.0 -519000.0 -1.39 145760.0 -483000.0 -1.32 -1.9168 -0.9997 3187001 PK04_093045 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C02 compound treatment 308570.0 -364000.0 -0.97 285440.0 -343000.0 -0.94 -1.3527 -0.9999 3068187 PK04_093046 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C03 compound treatment 550890.0 -121000.0 -0.32 441020.0 -187000.0 -0.51 -0.593 -0.9753 3187002 PK04_093047 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C04 compound treatment 595080.0 -77300.0 -0.21 446880.0 -181000.0 -0.5 -0.4982 -0.9239 3068188 PK04_093048 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C05 compound treatment 567140.0 -105000.0 -0.28 314560.0 -314000.0 -0.86 -0.8078 -0.8915 3187003 PK04_093049 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C06 compound treatment 471750.0 -201000.0 -0.54 326000.0 -302000.0 -0.83 -0.9658 -0.9776 3187004 PK04_093050 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C07 compound treatment 585510.0 -86800.0 -0.23 322470.0 -306000.0 -0.84 -0.7578 -0.8698 3068189 PK04_093051 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C08 compound treatment 444970.0 -227000.0 -0.61 211430.0 -417000.0 -1.14 -1.2388 -0.956 3187005 PK04_093052 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C09 compound treatment 707530.0 35200.0 0.09 538880.0 -89500.0 -0.25 -0.1072 -0.4076 3187006 PK04_093053 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C10 compound treatment 374670.0 -298000.0 -0.8 205330.0 -423000.0 -1.16 -1.3834 -0.9829 3068190 PK04_093054 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C11 mock treatment 702020.0 29700.0 0.08 598840.0 -29500.0 -0.08 -0.0012 -0.0107 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C12 mock treatment 497060.0 -175000.0 -0.47 347370.0 -281000.0 -0.77 -0.8765 -0.9714 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C13 compound treatment 420800.0 -252000.0 -0.67 251360.0 -377000.0 -1.03 -1.2069 -0.9781 3187007 PK04_093055 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C14 compound treatment 411040.0 -261000.0 -0.7 255060.0 -373000.0 -1.02 -1.2182 -0.9825 3068191 PK04_093056 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C15 mock treatment 546720.0 -126000.0 -0.34 570730.0 -57600.0 -0.16 -0.3491 -0.9411 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C16 mock treatment 473200.0 -199000.0 -0.53 599390.0 -29000.0 -0.08 -0.4323 -0.8039 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C17 compound treatment 256550.0 -416000.0 -1.11 291680.0 -337000.0 -0.92 -1.4388 -0.9958 3187008 PK04_093057 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C18 compound treatment 522880.0 -149000.0 -0.4 236000.0 -392000.0 -1.08 -1.0439 -0.9088 3068193 PK04_093058 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C19 compound treatment 493170.0 -179000.0 -0.48 336660.0 -292000.0 -0.8 -0.9046 -0.9697 3187009 PK04_093059 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C20 compound treatment 601140.0 -71200.0 -0.19 374370.0 -254000.0 -0.7 -0.6275 -0.8682 3187010 PK04_093060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C21 compound treatment 596800.0 -75500.0 -0.2 515740.0 -113000.0 -0.31 -0.3613 -0.9786 3068197 PK04_093061 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C22 compound treatment 452320.0 -220000.0 -0.59 334920.0 -293000.0 -0.81 -0.9852 -0.988 3187011 PK04_093062 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C23 compound treatment 375520.0 -297000.0 -0.79 717970.0 89600.0 0.25 -0.3866 -0.4657 3068199 PK04_093063 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 C24 compound treatment 570880.0 -101000.0 -0.27 604530.0 -23800.0 -0.07 -0.2378 -0.8533 3187012 PK04_093064 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCCCC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D01 compound treatment 740580.0 68200.0 0.18 624750.0 -3600.0 -0.01 0.1219 0.6678 3187091 PK04_093065 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D02 compound treatment 710400.0 38100.0 0.1 418660.0 -210000.0 -0.58 -0.3352 -0.5733 3068202 PK04_093066 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D03 compound treatment 767200.0 94900.0 0.25 655840.0 27500.0 0.08 0.2325 0.8795 3187092 PK04_093067 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D04 compound treatment 473500.0 -199000.0 -0.53 271200.0 -357000.0 -0.98 -1.0689 -0.9585 3187093 PK04_093068 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D05 compound treatment 476040.0 -196000.0 -0.52 253570.0 -375000.0 -1.03 -1.0983 -0.9511 3068220 PK04_093069 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D06 compound treatment 290530.0 -382000.0 -1.02 235840.0 -393000.0 -1.08 -1.4831 -0.9996 3187094 PK04_093070 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D07 compound treatment 757230.0 84900.0 0.23 497280.0 -131000.0 -0.36 -0.0941 -0.2212 3068223 PK04_093071 COC(=O)[C@H]1COC(=N1)c2ccc(OCCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D08 compound treatment 232160.0 -440000.0 -1.18 192270.0 -436000.0 -1.2 -1.6779 -1.0 3187095 PK04_093072 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D09 compound treatment 431550.0 -241000.0 -0.64 255360.0 -373000.0 -1.02 -1.1788 -0.9749 3068225 PK04_093073 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D10 compound treatment 784590.0 112000.0 0.3 799200.0 171000.0 0.47 0.5437 0.9766 3187096 PK04_093074 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D11 mock treatment 753960.0 81600.0 0.22 734400.0 106000.0 0.29 0.3601 0.9898 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D12 mock treatment 834720.0 162000.0 0.43 274350.0 -354000.0 -0.97 -0.3805 -0.3575 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D13 compound treatment 278590.0 -394000.0 -1.05 637280.0 8930.0 0.02 -0.7263 -0.6904 3187097 PK04_093075 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D14 compound treatment 357820.0 -315000.0 -0.84 285810.0 -343000.0 -0.94 -1.259 -0.9984 3068228 PK04_093076 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D15 mock treatment 700330.0 28000.0 0.07 420590.0 -208000.0 -0.57 -0.3504 -0.6092 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D16 mock treatment 807780.0 135000.0 0.36 488760.0 -140000.0 -0.38 -0.0152 -0.0288 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D17 compound treatment 612000.0 -60300.0 -0.16 770240.0 142000.0 0.39 0.1615 0.3831 3187098 PK04_093077 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D18 compound treatment 534040.0 -138000.0 -0.37 423330.0 -205000.0 -0.56 -0.6592 -0.9791 3187099 PK04_093078 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D19 compound treatment 395520.0 -277000.0 -0.74 644740.0 16400.0 0.05 -0.491 -0.6628 3068229 PK04_093079 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D20 compound treatment 470560.0 -202000.0 -0.54 508960.0 -119000.0 -0.33 -0.6128 -0.9716 3187100 PK04_093080 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D21 compound treatment 699860.0 27500.0 0.07 450080.0 -178000.0 -0.49 -0.2941 -0.5942 3068232 PK04_093081 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D22 compound treatment 561370.0 -111000.0 -0.3 343080.0 -285000.0 -0.78 -0.7634 -0.9116 3187101 PK04_093082 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D23 compound treatment 366600.0 -306000.0 -0.82 585610.0 -42700.0 -0.12 -0.6604 -0.8005 3187102 PK04_093083 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 D24 compound treatment 415680.0 -257000.0 -0.69 275010.0 -353000.0 -0.97 -1.1707 -0.9855 3068234 PK04_093084 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E01 mock treatment 862450.0 190000.0 0.51 821860.0 194000.0 0.53 0.7347 0.9997 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E02 mock treatment 805820.0 133000.0 0.36 771450.0 143000.0 0.39 0.5299 0.9988 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E03 compound treatment 704920.0 32600.0 0.09 449940.0 -178000.0 -0.49 -0.2848 -0.5725 3187103 PK04_093085 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E04 compound treatment 304540.0 -368000.0 -0.98 504880.0 -123000.0 -0.34 -0.9343 -0.8991 3187104 PK04_093086 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E05 compound treatment 856760.0 184000.0 0.49 849600.0 221000.0 0.61 0.7778 0.9946 3068237 PK04_093087 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E06 compound treatment 512160.0 -160000.0 -0.43 682110.0 53800.0 0.15 -0.1981 -0.4378 3187105 PK04_093088 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E07 compound treatment 317510.0 -355000.0 -0.95 214610.0 -414000.0 -1.14 -1.4733 -0.9959 3068240 PK04_093089 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E08 compound treatment 495590.0 -177000.0 -0.47 336410.0 -292000.0 -0.8 -0.9005 -0.9681 3187106 PK04_093090 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E09 mock treatment 772440.0 100000.0 0.27 798770.0 170000.0 0.47 0.5199 0.9648 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E10 mock treatment 821190.0 149000.0 0.4 827800.0 199000.0 0.55 0.6683 0.9876 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E11 compound treatment 385060.0 -287000.0 -0.77 315540.0 -313000.0 -0.86 -1.1498 -0.9984 3068242 PK04_093091 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E12 compound treatment 354240.0 -318000.0 -0.85 424540.0 -204000.0 -0.56 -0.9964 -0.9795 3187107 PK04_093092 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E13 compound treatment 258720.0 -414000.0 -1.1 278370.0 -350000.0 -0.96 -1.4606 -0.9976 3068264 PK04_093093 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E14 compound treatment 368970.0 -303000.0 -0.81 304070.0 -324000.0 -0.89 -1.2025 -0.9989 3187108 PK04_093094 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E15 compound treatment 605840.0 -66500.0 -0.18 245840.0 -383000.0 -1.05 -0.8681 -0.8151 3187109 PK04_093095 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E16 compound treatment 620660.0 -51700.0 -0.14 382450.0 -246000.0 -0.68 -0.575 -0.8344 3068267 PK04_093096 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E17 mock treatment 566510.0 -106000.0 -0.28 591650.0 -36700.0 -0.1 -0.2711 -0.9035 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E18 mock treatment 774830.0 102000.0 0.27 790590.0 162000.0 0.45 0.5085 0.9727 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E19 compound treatment 861560.0 189000.0 0.51 696290.0 67900.0 0.19 0.4893 0.9082 3187110 PK04_093097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E20 compound treatment 536900.0 -135000.0 -0.36 534790.0 -93600.0 -0.26 -0.4374 -0.9859 3187111 PK04_093098 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E21 compound treatment 459040.0 -213000.0 -0.57 569040.0 -59300.0 -0.16 -0.518 -0.8742 3068269 PK04_093099 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E22 compound treatment 458590.0 -214000.0 -0.57 449370.0 -179000.0 -0.49 -0.7511 -0.9972 3187184 PK04_093100 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E23 compound treatment 370640.0 -302000.0 -0.81 352960.0 -275000.0 -0.76 -1.1044 -0.9995 3068272 PK04_093101 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 E24 compound treatment 462150.0 -210000.0 -0.56 616370.0 -12000.0 -0.03 -0.4202 -0.7472 3187185 PK04_093102 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F01 mock treatment 862080.0 190000.0 0.51 725620.0 97300.0 0.27 0.5472 0.9552 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F02 mock treatment 685280.0 12900.0 0.03 428670.0 -200000.0 -0.55 -0.3632 -0.6612 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F03 compound treatment 416190.0 -256000.0 -0.68 299480.0 -329000.0 -0.9 -1.1222 -0.9906 3068274 PK04_093103 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F04 compound treatment 332640.0 -340000.0 -0.91 199560.0 -429000.0 -1.18 -1.474 -0.9917 3187186 PK04_093104 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F05 compound treatment 600010.0 -72300.0 -0.19 326280.0 -302000.0 -0.83 -0.723 -0.8491 3068276 PK04_093105 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F06 compound treatment 731150.0 58800.0 0.16 276000.0 -352000.0 -0.97 -0.5729 -0.5846 3187187 PK04_093106 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F07 compound treatment 339520.0 -333000.0 -0.89 427470.0 -201000.0 -0.55 -1.0185 -0.9736 3187188 PK04_093107 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F08 compound treatment 278080.0 -394000.0 -1.05 352580.0 -276000.0 -0.76 -1.28 -0.9869 3068278 PK04_093108 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F09 mock treatment 772640.0 100000.0 0.27 759890.0 132000.0 0.36 0.4448 0.9892 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F10 mock treatment 780480.0 108000.0 0.29 738250.0 110000.0 0.3 0.4176 0.9998 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F11 compound treatment 485820.0 -187000.0 -0.5 325170.0 -303000.0 -0.83 -0.9408 -0.9699 3187189 PK04_093109 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F12 compound treatment 323520.0 -349000.0 -0.93 471360.0 -157000.0 -0.43 -0.9636 -0.9386 3068280 PK04_093110 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F13 compound treatment 224640.0 -448000.0 -1.2 306760.0 -322000.0 -0.88 -1.4698 -0.9889 3187190 PK04_093111 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F14 compound treatment 268990.0 -403000.0 -1.08 494330.0 -134000.0 -0.37 -1.0219 -0.8977 3187191 PK04_093112 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F15 compound treatment 501360.0 -171000.0 -0.46 338760.0 -290000.0 -0.8 -0.8851 -0.9653 3068282 PK04_093113 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F16 compound treatment 354630.0 -318000.0 -0.85 292500.0 -336000.0 -0.92 -1.252 -0.9991 3187192 PK04_093114 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F17 mock treatment 523210.0 -149000.0 -0.4 453610.0 -175000.0 -0.48 -0.6209 -0.9957 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F18 mock treatment 555000.0 -117000.0 -0.31 465710.0 -163000.0 -0.45 -0.5373 -0.985 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F19 compound treatment 285680.0 -387000.0 -1.03 390830.0 -238000.0 -0.65 -1.1914 -0.9754 3187193 PK04_093115 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F20 compound treatment 720340.0 48000.0 0.13 471620.0 -157000.0 -0.43 -0.2136 -0.4757 3068312 PK04_093116 NC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F21 compound treatment 337000.0 -335000.0 -0.9 363910.0 -264000.0 -0.73 -1.1467 -0.9946 3068314 PK04_093117 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F22 compound treatment 715910.0 43600.0 0.12 651440.0 23100.0 0.06 0.1271 0.9592 3187194 PK04_093118 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F23 compound treatment 425000.0 -247000.0 -0.66 380440.0 -248000.0 -0.68 -0.9484 -0.9999 3187195 PK04_093119 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 F24 compound treatment 338260.0 -334000.0 -0.89 537440.0 -90900.0 -0.25 -0.8074 -0.8714 3068317 PK04_093120 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G01 compound treatment 700320.0 28000.0 0.07 455930.0 -172000.0 -0.47 -0.2819 -0.5881 3187196 PK04_093121 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G02 compound treatment 602000.0 -70300.0 -0.19 516500.0 -112000.0 -0.31 -0.35 -0.9722 3068319 PK04_093122 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCCCC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G03 mock treatment 828510.0 156000.0 0.42 831940.0 204000.0 0.56 0.6902 0.9896 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G04 mock treatment 612130.0 -60200.0 -0.16 566280.0 -62100.0 -0.17 -0.2342 -0.9996 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G05 compound treatment 424500.0 -248000.0 -0.66 591170.0 -37200.0 -0.1 -0.5402 -0.8066 3187197 PK04_093123 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G06 compound treatment 593610.0 -78700.0 -0.21 285240.0 -343000.0 -0.94 -0.8148 -0.8442 3187198 PK04_093124 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G07 compound treatment 742980.0 70600.0 0.19 341860.0 -286000.0 -0.79 -0.4227 -0.5226 3068323 PK04_093125 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G08 compound treatment 400050.0 -272000.0 -0.73 619360.0 -8990.0 -0.02 -0.5317 -0.7307 3187199 PK04_093126 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G09 compound treatment 708160.0 35800.0 0.1 702010.0 73700.0 0.2 0.2107 0.9416 3068325 PK04_093127 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G10 compound treatment 503370.0 -169000.0 -0.45 725920.0 97600.0 0.27 -0.1297 -0.2471 3187200 PK04_093128 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G11 compound treatment 268730.0 -404000.0 -1.08 587810.0 -40500.0 -0.11 -0.841 -0.776 3187201 PK04_093129 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G12 compound treatment 262830.0 -410000.0 -1.09 269930.0 -358000.0 -0.98 -1.4692 -0.9986 3068327 PK04_093130 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G13 compound treatment 259140.0 -413000.0 -1.1 212290.0 -416000.0 -1.14 -1.5881 -0.9999 3187202 PK04_093131 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G14 compound treatment 574250.0 -98100.0 -0.26 717760.0 89400.0 0.25 -0.0117 -0.0325 3187203 PK04_093132 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G15 compound treatment 411580.0 -261000.0 -0.7 483080.0 -145000.0 -0.4 -0.7745 -0.965 3068330 PK04_093133 COC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G16 compound treatment 247520.0 -425000.0 -1.13 271440.0 -357000.0 -0.98 -1.4952 -0.9973 3068332 PK04_093134 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G17 compound treatment 569980.0 -102000.0 -0.27 742750.0 114000.0 0.31 0.0288 0.0691 3187278 PK04_093135 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G18 compound treatment 300100.0 -372000.0 -0.99 307360.0 -321000.0 -0.88 -1.3262 -0.9982 3187279 PK04_093136 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G19 mock treatment 735530.0 63200.0 0.17 790010.0 162000.0 0.44 0.4332 0.9123 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G20 mock treatment 501660.0 -171000.0 -0.46 586910.0 -41400.0 -0.11 -0.4028 -0.8573 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G21 compound treatment 593890.0 -78400.0 -0.21 798520.0 170000.0 0.47 0.1822 0.3559 3187280 PK04_093137 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G22 compound treatment 307290.0 -365000.0 -0.98 256860.0 -371000.0 -1.02 -1.4106 -0.9997 3068361 PK04_093138 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G23 compound treatment 525250.0 -147000.0 -0.39 448160.0 -180000.0 -0.49 -0.6276 -0.9935 3187281 PK04_093139 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 G24 compound treatment 305230.0 -367000.0 -0.98 530500.0 -97800.0 -0.27 -0.8833 -0.8688 3187282 PK04_093140 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H01 compound treatment 346170.0 -326000.0 -0.87 242320.0 -386000.0 -1.06 -1.3654 -0.9953 3068365 PK04_093141 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H02 compound treatment 565120.0 -107000.0 -0.29 485610.0 -143000.0 -0.39 -0.4796 -0.9881 3187283 PK04_093142 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H03 mock treatment 698810.0 26500.0 0.07 831560.0 203000.0 0.56 0.4445 0.7904 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H04 mock treatment 486910.0 -185000.0 -0.5 822310.0 194000.0 0.53 0.0263 0.0362 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H05 compound treatment 266740.0 -406000.0 -1.08 352740.0 -276000.0 -0.76 -1.3011 -0.9846 3068368 PK04_093143 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H06 compound treatment 243320.0 -429000.0 -1.15 503400.0 -125000.0 -0.34 -1.0528 -0.8802 3187284 PK04_093144 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H07 compound treatment 341280.0 -331000.0 -0.88 282600.0 -346000.0 -0.95 -1.2964 -0.9994 3187285 PK04_093145 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H08 compound treatment 410130.0 -262000.0 -0.7 406470.0 -222000.0 -0.61 -0.9259 -0.9976 3068370 PK04_093146 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H09 compound treatment 445730.0 -227000.0 -0.61 376000.0 -252000.0 -0.69 -0.9179 -0.9977 3187286 PK04_093147 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H10 compound treatment 462210.0 -210000.0 -0.56 326660.0 -302000.0 -0.83 -0.9825 -0.982 3187287 PK04_093148 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H11 compound treatment 159050.0 -513000.0 -1.37 431400.0 -197000.0 -0.54 -1.3518 -0.9172 3068373 PK04_093149 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H12 compound treatment 485360.0 -187000.0 -0.5 307440.0 -321000.0 -0.88 -0.9761 -0.9638 3187288 PK04_093150 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H13 compound treatment 394900.0 -277000.0 -0.74 323430.0 -305000.0 -0.84 -1.1159 -0.9982 3187289 PK04_093151 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H14 compound treatment 319760.0 -353000.0 -0.94 393940.0 -234000.0 -0.64 -1.1209 -0.9828 3068375 PK04_093152 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H15 compound treatment 758620.0 86300.0 0.23 406370.0 -222000.0 -0.61 -0.268 -0.4113 3187290 PK04_093153 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CC=C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H16 compound treatment 250450.0 -422000.0 -1.13 583650.0 -44700.0 -0.12 -0.8836 -0.7795 3187291 PK04_093154 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H17 compound treatment 735680.0 63300.0 0.17 766630.0 138000.0 0.38 0.3881 0.9337 3068378 PK04_093155 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H18 compound treatment 523770.0 -149000.0 -0.4 597720.0 -30600.0 -0.08 -0.34 -0.8383 3187292 PK04_093156 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H19 mock treatment 819450.0 147000.0 0.39 537830.0 -90500.0 -0.25 0.1021 0.2197 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H20 mock treatment 872190.0 200000.0 0.53 792180.0 164000.0 0.45 0.6955 0.9964 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H21 compound treatment 394560.0 -278000.0 -0.74 319880.0 -308000.0 -0.85 -1.1234 -0.9978 3187293 PK04_093157 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H22 compound treatment 242790.0 -430000.0 -1.15 507700.0 -121000.0 -0.33 -1.0455 -0.8755 3068380 PK04_093158 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H23 compound treatment 393920.0 -278000.0 -0.74 380430.0 -248000.0 -0.68 -1.0071 -0.999 3068402 PK04_093159 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 H24 compound treatment 328250.0 -344000.0 -0.92 258820.0 -370000.0 -1.01 -1.3672 -0.9988 3187294 PK04_093160 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I01 compound treatment 759790.0 87500.0 0.23 625210.0 -3140.0 -0.01 0.1591 0.6806 3068406 PK04_093161 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I02 compound treatment 580870.0 -91500.0 -0.24 265770.0 -363000.0 -1.0 -0.8766 -0.8553 3187295 PK04_093162 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I03 compound treatment 346030.0 -326000.0 -0.87 321640.0 -307000.0 -0.84 -1.2117 -0.9999 3068409 PK04_093163 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I04 compound treatment 453060.0 -219000.0 -0.59 850240.0 222000.0 0.61 0.0166 0.0197 3187296 PK04_093164 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I05 mock treatment 587480.0 -84900.0 -0.23 699520.0 71200.0 0.2 -0.0221 -0.0738 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I06 mock treatment 781760.0 109000.0 0.29 851600.0 223000.0 0.61 0.6401 0.9426 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I07 compound treatment 205330.0 -467000.0 -1.25 311940.0 -316000.0 -0.87 -1.4963 -0.9844 3187297 PK04_093165 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I08 compound treatment 710120.0 37800.0 0.1 713600.0 85300.0 0.23 0.2369 0.9293 3068413 PK04_093166 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I09 compound treatment 434640.0 -238000.0 -0.63 540930.0 -87400.0 -0.24 -0.6186 -0.9115 3187298 PK04_093167 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I10 compound treatment 585480.0 -86900.0 -0.23 509730.0 -119000.0 -0.33 -0.3943 -0.9862 3187366 PK04_093168 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I11 compound treatment 721450.0 49100.0 0.13 484160.0 -144000.0 -0.4 -0.1871 -0.4487 3068416 PK04_093169 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I12 compound treatment 268960.0 -403000.0 -1.08 284570.0 -344000.0 -0.94 -1.4292 -0.9978 3187367 PK04_093170 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I13 compound treatment 814750.0 142000.0 0.38 804480.0 176000.0 0.48 0.6109 0.9929 3068419 PK04_093171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I14 compound treatment 417200.0 -255000.0 -0.68 517970.0 -110000.0 -0.3 -0.6961 -0.9334 3187368 PK04_093172 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I15 compound treatment 805700.0 133000.0 0.36 722880.0 94500.0 0.26 0.4354 0.9879 3068421 PK04_093173 COC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I16 compound treatment 202080.0 -470000.0 -1.26 221800.0 -407000.0 -1.12 -1.6774 -0.9983 3187369 PK04_093174 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I17 compound treatment 562840.0 -109000.0 -0.29 915840.0 287000.0 0.79 0.3513 0.4174 3068423 PK04_093175 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I18 compound treatment 486970.0 -185000.0 -0.5 887480.0 259000.0 0.71 0.153 0.1765 3187370 PK04_093176 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I19 compound treatment 505240.0 -167000.0 -0.45 586910.0 -41400.0 -0.11 -0.396 -0.8599 3187371 PK04_093177 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I20 compound treatment 683300.0 11000.0 0.03 532800.0 -95500.0 -0.26 -0.1648 -0.6242 3068425 PK04_093178 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I21 mock treatment 845050.0 173000.0 0.46 653920.0 25600.0 0.07 0.3759 0.8054 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I22 mock treatment 780110.0 108000.0 0.29 810890.0 183000.0 0.5 0.5579 0.9654 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I23 compound treatment 732350.0 60000.0 0.16 651770.0 23400.0 0.06 0.1588 0.9195 3187372 PK04_093179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 I24 compound treatment 334020.0 -338000.0 -0.9 310320.0 -318000.0 -0.87 -1.2563 -0.9999 3068456 PK04_093180 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J01 compound treatment 317680.0 -355000.0 -0.95 393720.0 -235000.0 -0.64 -1.1253 -0.9823 3187373 PK04_093181 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J02 compound treatment 143620.0 -529000.0 -1.41 208540.0 -420000.0 -1.15 -1.8135 -0.9949 3187374 PK04_093182 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J03 compound treatment 551470.0 -121000.0 -0.32 318770.0 -310000.0 -0.85 -0.8293 -0.9121 3068460 PK04_093183 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J04 compound treatment 780760.0 108000.0 0.29 572130.0 -56200.0 -0.15 0.0957 0.2915 3187375 PK04_093184 COCCCNC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J05 mock treatment 835370.0 163000.0 0.44 362500.0 -266000.0 -0.73 -0.2082 -0.2449 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J06 mock treatment 762110.0 89800.0 0.24 796230.0 168000.0 0.46 0.4955 0.9536 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J07 compound treatment 284320.0 -388000.0 -1.04 264570.0 -364000.0 -1.0 -1.439 -0.9998 3187376 PK04_093185 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J08 compound treatment 468160.0 -204000.0 -0.55 174480.0 -454000.0 -1.25 -1.2667 -0.9313 3068463 PK04_093186 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J09 compound treatment 365830.0 -307000.0 -0.82 666880.0 38500.0 0.11 -0.5041 -0.6107 3187377 PK04_093187 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J10 compound treatment 673920.0 1590.0 0.0 517760.0 -111000.0 -0.3 -0.2117 -0.6971 3068465 PK04_093188 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J11 compound treatment 231730.0 -441000.0 -1.18 577760.0 -50600.0 -0.14 -0.9304 -0.7851 3187378 PK04_093189 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J12 compound treatment 768390.0 96100.0 0.26 870170.0 242000.0 0.66 0.6509 0.9145 3068467 PK04_093190 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J13 compound treatment 295230.0 -377000.0 -1.01 681820.0 53500.0 0.15 -0.6084 -0.5977 3187379 PK04_093191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J14 compound treatment 190790.0 -482000.0 -1.29 570800.0 -57500.0 -0.16 -1.0212 -0.788 3187380 PK04_093192 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J15 compound treatment 559040.0 -113000.0 -0.3 619710.0 -8640.0 -0.02 -0.2307 -0.7602 3068470 PK04_093193 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J16 compound treatment 575740.0 -96600.0 -0.26 363380.0 -265000.0 -0.73 -0.6968 -0.9028 3187381 PK04_093194 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J17 compound treatment 522840.0 -149000.0 -0.4 808010.0 180000.0 0.49 0.0664 0.1047 3187382 PK04_093195 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J18 compound treatment 370880.0 -301000.0 -0.81 622080.0 -6270.0 -0.02 -0.5815 -0.7221 3068473 PK04_093196 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J19 compound treatment 535470.0 -137000.0 -0.37 573160.0 -55200.0 -0.15 -0.3656 -0.924 3187383 PK04_093197 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J20 compound treatment 338040.0 -334000.0 -0.89 580110.0 -48200.0 -0.13 -0.725 -0.8032 3068475 PK04_093198 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J21 mock treatment 601040.0 -71300.0 -0.19 395380.0 -233000.0 -0.64 -0.5869 -0.8795 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J22 mock treatment 692960.0 20600.0 0.06 443880.0 -184000.0 -0.51 -0.3191 -0.6265 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J23 compound treatment 540400.0 -132000.0 -0.35 512400.0 -116000.0 -0.32 -0.4743 -0.9987 3187384 PK04_093199 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 J24 compound treatment 201780.0 -471000.0 -1.26 296170.0 -332000.0 -0.91 -1.5336 -0.9876 3068477 PK04_093200 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K01 compound treatment 812240.0 140000.0 0.37 488590.0 -140000.0 -0.38 -0.0071 -0.0132 3187385 PK04_093201 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K02 compound treatment 350120.0 -322000.0 -0.86 472580.0 -156000.0 -0.43 -0.9109 -0.9479 3187386 PK04_093202 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K03 compound treatment 650010.0 -22300.0 -0.06 493480.0 -135000.0 -0.37 -0.304 -0.8105 3187447 PK04_093203 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K04 compound treatment 235470.0 -437000.0 -1.17 380600.0 -248000.0 -0.68 -1.306 -0.967 3068500 PK04_093204 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K05 compound treatment 402880.0 -269000.0 -0.72 350020.0 -278000.0 -0.76 -1.0492 -0.9996 3187448 PK04_093205 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K06 compound treatment 428760.0 -244000.0 -0.65 208080.0 -420000.0 -1.15 -1.2759 -0.9632 3187449 PK04_093206 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K07 mock treatment 859900.0 188000.0 0.5 688480.0 60100.0 0.17 0.471 0.8929 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K08 mock treatment 824990.0 153000.0 0.41 893150.0 265000.0 0.73 0.8024 0.9626 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K09 compound treatment 713400.0 41100.0 0.11 373120.0 -255000.0 -0.7 -0.4179 -0.5892 3068503 PK04_093207 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K10 compound treatment 425230.0 -247000.0 -0.66 668340.0 40000.0 0.11 -0.3891 -0.5815 3187450 PK04_093208 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K11 compound treatment 427250.0 -245000.0 -0.65 365000.0 -263000.0 -0.72 -0.9741 -0.9988 3068506 PK04_093209 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K12 compound treatment 389830.0 -283000.0 -0.75 405840.0 -223000.0 -0.61 -0.9655 -0.9945 3187451 PK04_093210 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K13 compound treatment 480130.0 -192000.0 -0.51 315800.0 -313000.0 -0.86 -0.9698 -0.9698 3187452 PK04_093211 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K14 compound treatment 758310.0 86000.0 0.23 766440.0 138000.0 0.38 0.4305 0.9712 3068509 PK04_093212 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K15 mock treatment 630300.0 -42000.0 -0.11 873220.0 245000.0 0.67 0.396 0.581 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K16 mock treatment 522480.0 -150000.0 -0.4 882660.0 254000.0 0.7 0.2107 0.2618 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K17 compound treatment 698800.0 26500.0 0.07 571050.0 -57300.0 -0.16 -0.0612 -0.3551 3187453 PK04_093213 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K18 compound treatment 379640.0 -293000.0 -0.78 542430.0 -85900.0 -0.24 -0.7196 -0.8812 3187454 PK04_093214 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K19 compound treatment 291730.0 -381000.0 -1.02 258720.0 -370000.0 -1.01 -1.4364 -1.0 3068511 PK04_093215 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K20 compound treatment 357460.0 -315000.0 -0.84 604540.0 -23800.0 -0.07 -0.6409 -0.7598 3187455 PK04_093216 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K21 compound treatment 767900.0 95600.0 0.26 538650.0 -89700.0 -0.25 0.0064 0.018 3068513 PK04_093217 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K22 compound treatment 531260.0 -141000.0 -0.38 427160.0 -201000.0 -0.55 -0.657 -0.9826 3187456 PK04_093218 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K23 mock treatment 624190.0 -48100.0 -0.13 617460.0 -10900.0 -0.03 -0.1121 -0.8489 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 K24 mock treatment 660910.0 -11400.0 -0.03 713120.0 84800.0 0.23 0.143 0.6092 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L01 compound treatment 207630.0 -465000.0 -1.24 262800.0 -366000.0 -1.0 -1.5873 -0.9944 3187457 PK04_093219 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L02 compound treatment 227530.0 -445000.0 -1.19 229170.0 -399000.0 -1.1 -1.615 -0.9992 3068516 PK04_093220 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L03 compound treatment 202630.0 -470000.0 -1.25 364360.0 -264000.0 -0.72 -1.3996 -0.966 3187458 PK04_093221 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L04 compound treatment 227530.0 -445000.0 -1.19 515300.0 -113000.0 -0.31 -1.0595 -0.8629 3187459 PK04_093222 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L05 compound treatment 334960.0 -337000.0 -0.9 224100.0 -404000.0 -1.11 -1.422 -0.9947 3068518 PK04_093223 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L06 compound treatment 255370.0 -417000.0 -1.11 358440.0 -270000.0 -0.74 -1.3115 -0.9804 3187460 PK04_093224 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L07 mock treatment 696050.0 23700.0 0.06 443620.0 -185000.0 -0.51 -0.3138 -0.614 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L08 mock treatment 320650.0 -352000.0 -0.94 216570.0 -412000.0 -1.13 -1.4636 -0.9958 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L09 compound treatment 308100.0 -364000.0 -0.97 396160.0 -232000.0 -0.64 -1.1387 -0.979 3068520 PK04_093225 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L10 compound treatment 860930.0 189000.0 0.5 809760.0 181000.0 0.5 0.7084 1.0 3187461 PK04_093226 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L11 compound treatment 299900.0 -372000.0 -0.99 398210.0 -230000.0 -0.63 -1.1502 -0.976 3187462 PK04_093227 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L12 compound treatment 387010.0 -285000.0 -0.76 282250.0 -346000.0 -0.95 -1.2108 -0.994 3187463 PK04_093228 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L13 compound treatment 299860.0 -372000.0 -0.99 217920.0 -410000.0 -1.13 -1.5002 -0.9981 3068543 PK04_093229 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L14 compound treatment 190210.0 -482000.0 -1.29 234720.0 -394000.0 -1.08 -1.6747 -0.9962 3187464 PK04_093230 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L15 mock treatment 824210.0 152000.0 0.41 688270.0 59900.0 0.16 0.4032 0.921 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L16 mock treatment 764960.0 92600.0 0.25 392370.0 -236000.0 -0.65 -0.2832 -0.4083 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L17 compound treatment 336570.0 -336000.0 -0.9 503430.0 -125000.0 -0.34 -0.8766 -0.913 3068545 PK04_093231 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L18 compound treatment 333280.0 -339000.0 -0.91 483070.0 -145000.0 -0.4 -0.9224 -0.9321 3187465 PK04_093232 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L19 compound treatment 539590.0 -133000.0 -0.35 545540.0 -82800.0 -0.23 -0.4115 -0.9769 3187466 PK04_093233 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L20 compound treatment 618530.0 -53800.0 -0.14 529010.0 -99300.0 -0.27 -0.2945 -0.9552 3068547 PK04_093234 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L21 compound treatment 413600.0 -259000.0 -0.69 465530.0 -163000.0 -0.45 -0.8047 -0.9778 3187467 PK04_093235 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CC=C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L22 compound treatment 302310.0 -370000.0 -0.99 332020.0 -296000.0 -0.81 -1.2741 -0.9953 3068549 PK04_093236 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L23 mock treatment 776360.0 104000.0 0.28 785560.0 157000.0 0.43 0.5017 0.9773 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 L24 mock treatment 412480.0 -260000.0 -0.69 621920.0 -6430.0 -0.02 -0.5033 -0.7249 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M01 compound treatment 324110.0 -348000.0 -0.93 262520.0 -366000.0 -1.0 -1.3679 -0.9993 3187528 PK04_093237 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M02 compound treatment 329780.0 -343000.0 -0.91 398170.0 -230000.0 -0.63 -1.0938 -0.9837 3187529 PK04_093238 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M03 compound treatment 688030.0 15700.0 0.04 637920.0 9570.0 0.03 0.0482 0.9747 3068551 PK04_093239 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M04 compound treatment 518820.0 -154000.0 -0.41 680330.0 52000.0 0.14 -0.189 -0.4354 3187530 PK04_093240 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M05 compound treatment 250840.0 -421000.0 -1.13 688130.0 59800.0 0.16 -0.68 -0.5977 3068553 PK04_093241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M06 compound treatment 176550.0 -496000.0 -1.32 287430.0 -341000.0 -0.94 -1.5982 -0.9856 3187531 PK04_093242 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M07 compound treatment 826040.0 154000.0 0.41 509640.0 -119000.0 -0.33 0.0599 0.1142 3187532 PK04_093243 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M08 compound treatment 190130.0 -482000.0 -1.29 228690.0 -400000.0 -1.1 -1.6866 -0.9968 3068555 PK04_093244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M09 mock treatment 696710.0 24400.0 0.07 773890.0 146000.0 0.4 0.3286 0.8116 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M10 mock treatment 841920.0 170000.0 0.45 781180.0 153000.0 0.42 0.617 0.9993 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M11 compound treatment 639370.0 -33000.0 -0.09 803840.0 175000.0 0.48 0.2784 0.5685 3187533 PK04_093245 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M12 compound treatment 234840.0 -437000.0 -1.17 304500.0 -324000.0 -0.89 -1.455 -0.9909 3187534 PK04_093246 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M13 mock treatment 776850.0 105000.0 0.28 475090.0 -153000.0 -0.42 -0.1001 -0.1983 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M14 mock treatment 456590.0 -216000.0 -0.58 857120.0 229000.0 0.63 0.0367 0.043 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M15 compound treatment 765490.0 93200.0 0.25 747860.0 120000.0 0.33 0.408 0.9907 3068558 PK04_093247 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M16 compound treatment 756700.0 84400.0 0.23 876580.0 248000.0 0.68 0.6412 0.8934 3187535 PK04_093248 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M17 compound treatment 870930.0 199000.0 0.53 711110.0 82800.0 0.23 0.5358 0.9284 3068560 PK04_093249 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M18 compound treatment 552320.0 -120000.0 -0.32 356920.0 -271000.0 -0.75 -0.7536 -0.929 3187536 PK04_093250 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M19 compound treatment 844540.0 172000.0 0.46 727440.0 99100.0 0.27 0.5176 0.9686 3187537 PK04_093251 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M20 compound treatment 665970.0 -6360.0 -0.02 769660.0 141000.0 0.39 0.2623 0.6755 3068562 PK04_093252 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCOCC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M21 compound treatment 770770.0 98400.0 0.26 783540.0 155000.0 0.43 0.4872 0.9731 3068586 PK04_093253 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M22 compound treatment 694180.0 21800.0 0.06 674280.0 45900.0 0.13 0.1304 0.9387 3187538 PK04_093254 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M23 compound treatment 183710.0 -489000.0 -1.31 190340.0 -438000.0 -1.2 -1.7732 -0.9992 3068589 PK04_093255 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 M24 compound treatment 244080.0 -428000.0 -1.14 506510.0 -122000.0 -0.33 -1.0454 -0.8772 3187539 PK04_093256 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N01 compound treatment 296500.0 -376000.0 -1.0 201390.0 -427000.0 -1.17 -1.5387 -0.997 3187540 PK04_093257 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N02 compound treatment 217130.0 -455000.0 -1.22 192490.0 -436000.0 -1.2 -1.7059 -1.0 3187541 PK04_093258 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N03 compound treatment 452710.0 -220000.0 -0.59 455410.0 -173000.0 -0.47 -0.7505 -0.9945 3068594 PK04_093259 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CC=C)C3=O)[C@@H](O2)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N04 compound treatment 539840.0 -132000.0 -0.35 434400.0 -194000.0 -0.53 -0.6267 -0.9803 3187542 PK04_093260 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N05 compound treatment 374850.0 -297000.0 -0.79 329040.0 -299000.0 -0.82 -1.1429 -0.9999 3068597 PK04_093261 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CC=C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N06 compound treatment 535700.0 -137000.0 -0.36 561520.0 -66800.0 -0.18 -0.3878 -0.9494 3187543 PK04_093262 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N07 compound treatment 195840.0 -476000.0 -1.27 260160.0 -368000.0 -1.01 -1.6147 -0.9935 3187544 PK04_093263 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CC=C)C3=O)[C@H](O2)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N08 compound treatment 240010.0 -432000.0 -1.15 263260.0 -365000.0 -1.0 -1.5253 -0.9975 3068600 PK04_093264 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N09 mock treatment 831040.0 159000.0 0.42 817760.0 189000.0 0.52 0.6675 0.9949 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N10 mock treatment 578310.0 -94000.0 -0.25 488020.0 -140000.0 -0.39 -0.45 -0.9785 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N11 compound treatment 199900.0 -472000.0 -1.26 247910.0 -380000.0 -1.04 -1.6308 -0.9956 3187545 PK04_093265 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N12 compound treatment 336440.0 -336000.0 -0.9 620600.0 -7750.0 -0.02 -0.6494 -0.7237 3187546 PK04_093266 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N13 mock treatment 572500.0 -99800.0 -0.27 907530.0 279000.0 0.77 0.3534 0.4355 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N14 mock treatment 843520.0 171000.0 0.46 917940.0 290000.0 0.8 0.8855 0.9655 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N15 compound treatment 262330.0 -410000.0 -1.1 235840.0 -393000.0 -1.08 -1.5363 -1.0 3068603 PK04_093267 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N16 compound treatment 497200.0 -175000.0 -0.47 678630.0 50300.0 0.14 -0.2332 -0.4781 3187547 PK04_093268 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N17 compound treatment 669810.0 -2520.0 -0.01 783000.0 155000.0 0.42 0.2955 0.6958 3068605 PK04_093269 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N18 compound treatment 371800.0 -301000.0 -0.8 473710.0 -155000.0 -0.42 -0.8678 -0.9557 3187548 PK04_093270 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N19 compound treatment 572640.0 -99700.0 -0.27 791330.0 163000.0 0.45 0.1281 0.2461 3068607 PK04_093271 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CC=C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N20 compound treatment 599840.0 -72500.0 -0.19 642440.0 14100.0 0.04 -0.1096 -0.5549 3186297 PK04_093272 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N21 compound treatment 402800.0 -270000.0 -0.72 629120.0 771.0 0.0 -0.5076 -0.705 3186298 PK04_093273 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CC=C)C3=O)[C@@H](O2)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N22 compound treatment 467710.0 -205000.0 -0.55 760960.0 133000.0 0.36 -0.129 -0.1965 3068610 PK04_093274 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N23 compound treatment 315940.0 -356000.0 -0.95 298640.0 -330000.0 -0.91 -1.3132 -0.9997 3068635 PK04_093275 CC(=O)N1Cc2ccccc2C[C@]3(N=C(O[C@@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 N24 compound treatment 363460.0 -309000.0 -0.82 564320.0 -64000.0 -0.18 -0.7077 -0.8389 3186299 PK04_093276 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O01 compound treatment 225310.0 -447000.0 -1.19 249280.0 -379000.0 -1.04 -1.5802 -0.9977 3068638 PK04_093277 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O02 compound treatment 312820.0 -360000.0 -0.96 205570.0 -423000.0 -1.16 -1.4997 -0.9956 3186300 PK04_093278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O03 compound treatment 267050.0 -405000.0 -1.08 322630.0 -306000.0 -0.84 -1.3589 -0.9921 3068640 PK04_093279 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O04 compound treatment 713550.0 41200.0 0.11 704410.0 76100.0 0.21 0.2255 0.9553 3186301 PK04_093280 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O05 compound treatment 463160.0 -209000.0 -0.56 635860.0 7510.0 0.02 -0.3805 -0.6805 3068642 PK04_093281 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O06 compound treatment 737710.0 65400.0 0.17 394800.0 -234000.0 -0.64 -0.3299 -0.4964 3186302 PK04_093282 COCCCNC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O07 compound treatment 676240.0 3910.0 0.01 332160.0 -296000.0 -0.81 -0.5676 -0.698 3186303 PK04_093283 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O08 compound treatment 462780.0 -210000.0 -0.56 485300.0 -143000.0 -0.39 -0.6735 -0.985 3068645 PK04_093284 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O09 compound treatment 198290.0 -474000.0 -1.27 152280.0 -476000.0 -1.31 -1.8195 -0.9999 3186304 PK04_093285 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O10 compound treatment 176930.0 -495000.0 -1.32 241870.0 -386000.0 -1.06 -1.6859 -0.994 3186305 PK04_093286 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O11 mock treatment 387960.0 -284000.0 -0.76 752080.0 124000.0 0.34 -0.2969 -0.3568 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O12 mock treatment 607640.0 -64700.0 -0.17 736440.0 108000.0 0.3 0.0877 0.2553 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O13 compound treatment 299110.0 -373000.0 -1.0 448590.0 -180000.0 -0.49 -1.0539 -0.9474 3068648 PK04_093287 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O14 compound treatment 284210.0 -388000.0 -1.04 278950.0 -349000.0 -0.96 -1.4113 -0.9992 3186306 PK04_093288 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O15 compound treatment 408320.0 -264000.0 -0.71 409440.0 -219000.0 -0.6 -0.9236 -0.9968 3068650 PK04_093289 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O16 compound treatment 263070.0 -409000.0 -1.09 330090.0 -298000.0 -0.82 -1.352 -0.9899 3186307 PK04_093290 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O17 compound treatment 577540.0 -94800.0 -0.25 637470.0 9120.0 0.03 -0.1613 -0.6341 3186308 PK04_093291 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O18 compound treatment 411100.0 -261000.0 -0.7 471650.0 -157000.0 -0.43 -0.7976 -0.973 3068652 PK04_093292 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O19 compound treatment 210300.0 -462000.0 -1.23 220130.0 -408000.0 -1.12 -1.6651 -0.9988 3186309 PK04_093293 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O20 compound treatment 342080.0 -330000.0 -0.88 500060.0 -128000.0 -0.35 -0.8728 -0.9189 3068654 PK04_093294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O21 compound treatment 100660.0 -572000.0 -1.53 123240.0 -505000.0 -1.39 -2.0603 -0.9988 3186310 PK04_093295 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O22 compound treatment 322150.0 -350000.0 -0.94 340720.0 -288000.0 -0.79 -1.2198 -0.9965 3186311 PK04_093296 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O23 compound treatment 422340.0 -250000.0 -0.67 409610.0 -219000.0 -0.6 -0.8968 -0.9986 3068656 PK04_093297 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 O24 compound treatment 257280.0 -415000.0 -1.11 307420.0 -321000.0 -0.88 -1.4069 -0.9935 3186312 PK04_093298 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P01 compound treatment 167110.0 -505000.0 -1.35 225960.0 -402000.0 -1.1 -1.7354 -0.9951 3186313 PK04_093299 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P02 compound treatment 141070.0 -531000.0 -1.42 141120.0 -487000.0 -1.34 -1.9492 -0.9996 3186314 PK04_093300 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P03 compound treatment 173020.0 -499000.0 -1.33 162320.0 -466000.0 -1.28 -1.8477 -0.9998 3067960 PK04_093301 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P04 compound treatment 191750.0 -481000.0 -1.28 160220.0 -468000.0 -1.29 -1.8164 -1.0 3186315 PK04_093302 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P05 compound treatment 243210.0 -429000.0 -1.15 288740.0 -340000.0 -0.93 -1.4698 -0.9948 3186316 PK04_093303 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CC=C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P06 compound treatment 158320.0 -514000.0 -1.37 208590.0 -420000.0 -1.15 -1.7857 -0.9962 3067963 PK04_093304 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P07 compound treatment 207730.0 -465000.0 -1.24 399580.0 -229000.0 -0.63 -1.3216 -0.9502 3186317 PK04_093305 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CC=C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P08 compound treatment 329120.0 -343000.0 -0.92 250620.0 -378000.0 -1.04 -1.3815 -0.9981 3186362 PK04_093306 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P09 compound treatment 197880.0 -474000.0 -1.27 194560.0 -434000.0 -1.19 -1.7382 -0.9995 3067965 PK04_093307 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P10 compound treatment 217890.0 -454000.0 -1.21 192750.0 -436000.0 -1.2 -1.7039 -1.0 3186363 PK04_093308 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P11 mock treatment 539380.0 -133000.0 -0.36 306670.0 -322000.0 -0.88 -0.8756 -0.9199 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P12 mock treatment 216530.0 -456000.0 -1.22 239790.0 -389000.0 -1.07 -1.6152 -0.9978 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P13 compound treatment 220890.0 -451000.0 -1.21 237370.0 -391000.0 -1.07 -1.6116 -0.9983 3186364 PK04_093309 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P14 compound treatment 222810.0 -450000.0 -1.2 253250.0 -375000.0 -1.03 -1.5772 -0.9971 3067968 PK04_093310 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P15 compound treatment 190580.0 -482000.0 -1.29 164830.0 -464000.0 -1.27 -1.8097 -1.0 3186365 PK04_093311 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P16 compound treatment 266490.0 -406000.0 -1.08 236490.0 -392000.0 -1.08 -1.5272 -1.0 3186366 PK04_093312 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P17 compound treatment 238560.0 -434000.0 -1.16 279790.0 -349000.0 -0.96 -1.4959 -0.9955 3067970 PK04_093313 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P18 compound treatment 181530.0 -491000.0 -1.31 210410.0 -418000.0 -1.15 -1.7383 -0.9978 3186367 PK04_093314 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P19 compound treatment 183580.0 -489000.0 -1.31 334960.0 -293000.0 -0.81 -1.4926 -0.9731 3067972 PK04_093315 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CC=C)C3=O)[C@H](O2)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P20 compound treatment 173390.0 -499000.0 -1.33 311060.0 -317000.0 -0.87 -1.5583 -0.9788 3186368 PK04_093316 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P21 compound treatment 132340.0 -540000.0 -1.44 167840.0 -461000.0 -1.26 -1.9139 -0.9978 3067974 PK04_093317 CC(=O)N1Cc2ccccc2C[C@@]3(N=C(O[C@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P22 compound treatment 299530.0 -373000.0 -1.0 228800.0 -400000.0 -1.1 -1.4797 -0.9988 3186369 PK04_093318 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P23 compound treatment 303200.0 -369000.0 -0.99 367200.0 -261000.0 -0.72 -1.2041 -0.9878 3067976 PK04_093319 CC(=O)N1Cc2ccccc2C[C@@]3(COC(=N3)c4ccc(OCCCO)cc4)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2093 P24 compound treatment 100810.0 -572000.0 -1.53 173320.0 -455000.0 -1.25 -1.9628 -0.995 3186370 PK04_093320 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A01 compound treatment 164800.0 -560000.0 -1.49 182040.0 -346000.0 -0.95 -1.7284 -0.976 3186371 PK04_094001 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A02 compound treatment 348030.0 -376000.0 -1.01 178520.0 -349000.0 -0.96 -1.3891 -0.9997 3067979 PK04_094002 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A03 compound treatment 283440.0 -441000.0 -1.18 221210.0 -307000.0 -0.84 -1.4283 -0.9865 3068002 PK04_094003 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A04 compound treatment 710000.0 -14400.0 -0.04 203270.0 -325000.0 -0.89 -0.6575 -0.7369 3186372 PK04_094004 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A05 compound treatment 208510.0 -516000.0 -1.38 299580.0 -228000.0 -0.63 -1.4176 -0.9364 3068007 PK04_094005 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A06 compound treatment 287200.0 -437000.0 -1.17 196100.0 -332000.0 -0.91 -1.4699 -0.9925 3186373 PK04_094006 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A07 compound treatment 253600.0 -471000.0 -1.26 296030.0 -232000.0 -0.64 -1.3394 -0.9503 3186374 PK04_094007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A08 compound treatment 351520.0 -373000.0 -1.0 387410.0 -141000.0 -0.39 -0.977 -0.9148 3068010 PK04_094008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A09 compound treatment 512380.0 -212000.0 -0.57 362590.0 -165000.0 -0.45 -0.7214 -0.994 3186375 PK04_094009 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A10 compound treatment 320000.0 -404000.0 -1.08 359550.0 -168000.0 -0.46 -1.0906 -0.9283 3068013 PK04_094010 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A11 compound treatment 195410.0 -529000.0 -1.41 239480.0 -288000.0 -0.79 -1.559 -0.9625 3186376 PK04_094011 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A12 compound treatment 199680.0 -525000.0 -1.4 233930.0 -294000.0 -0.81 -1.5618 -0.9656 3186377 PK04_094012 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A13 mock treatment 387410.0 -337000.0 -0.9 267580.0 -260000.0 -0.71 -1.1419 -0.9935 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A14 mock treatment 485120.0 -239000.0 -0.64 373860.0 -154000.0 -0.42 -0.751 -0.9799 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A15 compound treatment 543270.0 -181000.0 -0.48 234180.0 -294000.0 -0.81 -0.9123 -0.9701 3068016 PK04_094013 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A16 compound treatment 343370.0 -381000.0 -1.02 286530.0 -241000.0 -0.66 -1.1883 -0.9784 3186378 PK04_094014 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A17 compound treatment 336000.0 -388000.0 -1.04 303370.0 -225000.0 -0.62 -1.1695 -0.9691 3068018 PK04_094015 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A18 compound treatment 279210.0 -445000.0 -1.19 227120.0 -301000.0 -0.83 -1.4248 -0.9841 3186379 PK04_094016 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A19 compound treatment 356840.0 -368000.0 -0.98 235470.0 -292000.0 -0.8 -1.2619 -0.995 3186380 PK04_094017 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A20 compound treatment 418660.0 -306000.0 -0.82 516550.0 -11400.0 -0.03 -0.5995 -0.7336 3068020 PK04_094018 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A21 compound treatment 276330.0 -448000.0 -1.2 412160.0 -116000.0 -0.32 -1.071 -0.8649 3186381 PK04_094019 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A22 compound treatment 693010.0 -31400.0 -0.08 566950.0 39000.0 0.11 0.0165 0.1211 3186437 PK04_094020 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A23 compound treatment 513780.0 -211000.0 -0.56 453990.0 -73900.0 -0.2 -0.5413 -0.9051 3068021 PK04_094021 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 A24 compound treatment 314730.0 -410000.0 -1.09 346900.0 -181000.0 -0.5 -1.1252 -0.9362 3186438 PK04_094022 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B01 compound treatment 788080.0 63700.0 0.17 693250.0 165000.0 0.45 0.4412 0.9103 3186439 PK04_094023 CCCN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B02 compound treatment 685550.0 -38900.0 -0.1 426200.0 -102000.0 -0.28 -0.2709 -0.9091 3089331 PK04_094024 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B03 compound treatment 327010.0 -397000.0 -1.06 296520.0 -231000.0 -0.64 -1.1998 -0.9699 3068022 PK04_094025 CCCN1C(=O)[C@]2(Cc3ccccc13)N=C(O[C@@H]2c4ccccc4)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B04 compound treatment 614850.0 -110000.0 -0.29 296580.0 -231000.0 -0.64 -0.656 -0.9381 3089332 PK04_094026 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B05 compound treatment 375360.0 -349000.0 -0.93 327530.0 -200000.0 -0.55 -1.0482 -0.9683 3186440 PK04_094027 CCCN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B06 compound treatment 601800.0 -123000.0 -0.33 356720.0 -171000.0 -0.47 -0.5639 -0.9844 3000708 PK04_094028 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B07 compound treatment 728500.0 4090.0 0.01 330740.0 -197000.0 -0.54 -0.3751 -0.6927 3068023 PK04_094029 CN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B08 compound treatment 471580.0 -253000.0 -0.68 691600.0 164000.0 0.45 -0.1597 -0.1969 3089333 PK04_094030 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B09 compound treatment 323490.0 -401000.0 -1.07 390790.0 -137000.0 -0.38 -1.0234 -0.9016 3186441 PK04_094031 CN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B10 compound treatment 357520.0 -367000.0 -0.98 368020.0 -160000.0 -0.44 -1.0033 -0.9344 3089654 PK04_094032 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B11 compound treatment 252480.0 -472000.0 -1.26 241410.0 -287000.0 -0.79 -1.4475 -0.9742 3186442 PK04_094033 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B12 compound treatment 532430.0 -192000.0 -0.51 178370.0 -350000.0 -0.96 -1.0412 -0.9569 3089334 PK04_094034 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B13 mock treatment 737770.0 13400.0 0.04 378360.0 -150000.0 -0.41 -0.2651 -0.6432 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B14 mock treatment 876340.0 152000.0 0.41 717770.0 190000.0 0.52 0.6555 0.9923 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B15 compound treatment 363650.0 -361000.0 -0.96 343720.0 -184000.0 -0.51 -1.0389 -0.9547 3068024 PK04_094035 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B16 compound treatment 268850.0 -456000.0 -1.22 308970.0 -219000.0 -0.6 -1.2854 -0.9472 3000709 PK04_094036 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B17 compound treatment 552610.0 -172000.0 -0.46 420520.0 -107000.0 -0.29 -0.533 -0.9771 3186443 PK04_094037 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B18 compound treatment 338440.0 -386000.0 -1.03 196680.0 -331000.0 -0.91 -1.372 -0.998 3089363 PK04_094038 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B19 compound treatment 313920.0 -410000.0 -1.1 255280.0 -273000.0 -0.75 -1.3045 -0.9827 3068025 PK04_094039 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B20 compound treatment 211130.0 -513000.0 -1.37 207360.0 -321000.0 -0.88 -1.5917 -0.977 3089652 PK04_094040 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B21 compound treatment 435530.0 -289000.0 -0.77 397940.0 -130000.0 -0.36 -0.7979 -0.9386 3186444 PK04_094041 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B22 compound treatment 330130.0 -394000.0 -1.05 263070.0 -265000.0 -0.73 -1.2588 -0.9836 3089653 PK04_094042 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B23 compound treatment 382330.0 -342000.0 -0.91 297170.0 -231000.0 -0.63 -1.094 -0.984 3186445 PK04_094043 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 B24 compound treatment 470000.0 -254000.0 -0.68 298530.0 -229000.0 -0.63 -0.9258 -0.9993 3089657 PK04_094044 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C01 compound treatment 563200.0 -161000.0 -0.43 418180.0 -110000.0 -0.3 -0.5175 -0.9847 3068026 PK04_094045 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C02 compound treatment 441600.0 -283000.0 -0.76 269570.0 -258000.0 -0.71 -1.0357 -0.9995 3068051 PK04_094046 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C03 compound treatment 310120.0 -414000.0 -1.11 344570.0 -183000.0 -0.5 -1.1384 -0.9364 3068052 PK04_094047 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C04 compound treatment 568210.0 -156000.0 -0.42 639550.0 112000.0 0.31 -0.0783 -0.1512 3068053 PK04_094048 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCOCC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C05 compound treatment 431680.0 -293000.0 -0.78 240850.0 -287000.0 -0.79 -1.1102 -1.0 3068054 PK04_094049 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C06 compound treatment 768550.0 44100.0 0.12 340830.0 -187000.0 -0.51 -0.2798 -0.531 3186446 PK04_094050 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C07 compound treatment 663490.0 -60900.0 -0.16 624240.0 96300.0 0.26 0.0719 0.2317 3068055 PK04_094051 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C08 compound treatment 748640.0 24200.0 0.06 658840.0 131000.0 0.36 0.2999 0.8212 3186447 PK04_094052 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C09 compound treatment 475040.0 -249000.0 -0.67 528060.0 141.0 0.0 -0.4707 -0.7067 3068056 PK04_094053 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C10 compound treatment 323040.0 -401000.0 -1.07 188800.0 -339000.0 -0.93 -1.4164 -0.9975 3186448 PK04_094054 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C11 mock treatment 808440.0 84000.0 0.22 566660.0 38700.0 0.11 0.2339 0.9418 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C12 mock treatment 776090.0 51700.0 0.14 791360.0 263000.0 0.72 0.609 0.8271 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C13 compound treatment 728410.0 4000.0 0.01 336880.0 -191000.0 -0.52 -0.3633 -0.6925 3186449 PK04_094055 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C14 compound treatment 548420.0 -176000.0 -0.47 295750.0 -232000.0 -0.64 -0.7831 -0.9888 3068057 PK04_094056 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C15 mock treatment 652640.0 -71800.0 -0.19 618240.0 90300.0 0.25 0.0398 0.127 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C16 mock treatment 489510.0 -235000.0 -0.63 622090.0 94200.0 0.26 -0.2608 -0.3844 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C17 compound treatment 423640.0 -301000.0 -0.8 234530.0 -293000.0 -0.81 -1.1376 -1.0 3186450 PK04_094057 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C18 compound treatment 363130.0 -361000.0 -0.96 302560.0 -225000.0 -0.62 -1.1198 -0.9769 3186451 PK04_094058 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C19 compound treatment 628560.0 -95800.0 -0.26 551690.0 23800.0 0.07 -0.1349 -0.5105 3068058 PK04_094059 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C20 compound treatment 219360.0 -505000.0 -1.35 220430.0 -307000.0 -0.84 -1.5508 -0.9745 3186452 PK04_094060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C21 compound treatment 251200.0 -473000.0 -1.26 452030.0 -75900.0 -0.21 -1.0411 -0.8127 3068059 PK04_094061 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C22 compound treatment 437710.0 -287000.0 -0.77 380800.0 -147000.0 -0.4 -0.8271 -0.9553 3186453 PK04_094062 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C23 compound treatment 356040.0 -368000.0 -0.98 588640.0 60700.0 0.17 -0.5778 -0.579 3186454 PK04_094063 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 C24 compound treatment 578360.0 -146000.0 -0.39 770190.0 242000.0 0.67 0.1945 0.2522 3068060 PK04_094064 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D01 compound treatment 851750.0 127000.0 0.34 770180.0 242000.0 0.67 0.7108 0.9515 3186455 PK04_094065 CN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D02 compound treatment 334120.0 -390000.0 -1.04 259950.0 -268000.0 -0.74 -1.2573 -0.9854 3000713 PK04_094066 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D03 compound treatment 385640.0 -339000.0 -0.9 368680.0 -159000.0 -0.44 -0.9489 -0.9443 3186456 PK04_094067 CCCN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D04 compound treatment 329190.0 -395000.0 -1.06 444750.0 -83200.0 -0.23 -0.9079 -0.8406 3089658 PK04_094068 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D05 compound treatment 322610.0 -402000.0 -1.07 659250.0 131000.0 0.36 -0.5039 -0.4451 3068061 PK04_094069 CCCN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D06 compound treatment 523900.0 -201000.0 -0.54 399230.0 -129000.0 -0.35 -0.6285 -0.9796 3089659 PK04_094070 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D07 compound treatment 496480.0 -228000.0 -0.61 374580.0 -153000.0 -0.42 -0.7282 -0.9838 3186457 PK04_094071 CCCN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D08 compound treatment 512100.0 -212000.0 -0.57 369610.0 -158000.0 -0.43 -0.7083 -0.9914 3089664 PK04_094072 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D09 compound treatment 323160.0 -401000.0 -1.07 610580.0 82700.0 0.23 -0.5974 -0.5453 3068062 PK04_094073 CCCN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D10 compound treatment 382990.0 -341000.0 -0.91 252320.0 -276000.0 -0.76 -1.1798 -0.9957 3000714 PK04_094074 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D11 mock treatment 924200.0 200000.0 0.53 343200.0 -185000.0 -0.51 0.0187 0.0255 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D12 mock treatment 886800.0 162000.0 0.43 807450.0 280000.0 0.77 0.8494 0.9635 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D13 compound treatment 354180.0 -370000.0 -0.99 285130.0 -243000.0 -0.67 -1.1706 -0.9816 3186504 PK04_094075 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D14 compound treatment 352880.0 -372000.0 -0.99 264540.0 -263000.0 -0.72 -1.213 -0.9879 3089660 PK04_094076 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D15 mock treatment 653780.0 -70600.0 -0.19 328330.0 -200000.0 -0.55 -0.5209 -0.8988 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D16 mock treatment 865920.0 142000.0 0.38 596750.0 68800.0 0.19 0.4009 0.9487 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D17 compound treatment 393600.0 -331000.0 -0.88 303390.0 -225000.0 -0.62 -1.0607 -0.9845 3186505 PK04_094077 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D18 compound treatment 483760.0 -241000.0 -0.64 402250.0 -126000.0 -0.35 -0.6985 -0.9574 3000715 PK04_094078 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D19 compound treatment 359840.0 -365000.0 -0.97 250240.0 -278000.0 -0.76 -1.2276 -0.9927 3068063 PK04_094079 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(Cc5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D20 compound treatment 318500.0 -406000.0 -1.08 254130.0 -274000.0 -0.75 -1.2981 -0.984 3089662 PK04_094080 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D21 compound treatment 288700.0 -436000.0 -1.16 271690.0 -256000.0 -0.7 -1.3203 -0.9709 3186506 PK04_094081 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D22 compound treatment 452370.0 -272000.0 -0.73 293010.0 -235000.0 -0.64 -0.9698 -0.9982 3000716 PK04_094082 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D23 compound treatment 408800.0 -316000.0 -0.84 444000.0 -83900.0 -0.23 -0.759 -0.8685 3068064 PK04_094083 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 D24 compound treatment 160970.0 -563000.0 -1.5 163840.0 -364000.0 -1.0 -1.7709 -0.9802 3000811 PK04_094084 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E01 mock treatment 451960.0 -272000.0 -0.73 601280.0 73400.0 0.2 -0.3721 -0.4929 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E02 mock treatment 940690.0 216000.0 0.58 693680.0 166000.0 0.46 0.7303 0.993 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E03 compound treatment 701790.0 -22600.0 -0.06 437930.0 -90000.0 -0.25 -0.2174 -0.8548 3186507 PK04_094085 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E04 compound treatment 388070.0 -336000.0 -0.9 456090.0 -71800.0 -0.2 -0.7747 -0.8423 3186508 PK04_094086 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E05 compound treatment 811470.0 87100.0 0.23 646910.0 119000.0 0.33 0.3954 0.9861 3068065 PK04_094087 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E06 compound treatment 358030.0 -366000.0 -0.98 233310.0 -295000.0 -0.81 -1.2639 -0.9955 3186509 PK04_094088 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E07 compound treatment 324350.0 -400000.0 -1.07 296710.0 -231000.0 -0.63 -1.2044 -0.9691 3068066 PK04_094089 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E08 compound treatment 556170.0 -168000.0 -0.45 345280.0 -183000.0 -0.5 -0.6723 -0.9985 3186510 PK04_094090 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E09 mock treatment 922340.0 198000.0 0.53 494600.0 -33300.0 -0.09 0.3092 0.5762 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E10 mock treatment 610010.0 -114000.0 -0.31 631080.0 103000.0 0.28 -0.0158 -0.0379 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E11 compound treatment 263970.0 -460000.0 -1.23 365630.0 -162000.0 -0.45 -1.1847 -0.9057 3186511 PK04_094091 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E12 compound treatment 951080.0 227000.0 0.61 482690.0 -45200.0 -0.12 0.3403 0.5506 3068067 PK04_094092 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E13 compound treatment 356160.0 -368000.0 -0.98 486420.0 -41500.0 -0.11 -0.7761 -0.7838 3186512 PK04_094093 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E14 compound treatment 439590.0 -285000.0 -0.76 205930.0 -322000.0 -0.88 -1.163 -0.9972 3068068 PK04_094094 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E15 compound treatment 433680.0 -291000.0 -0.78 484560.0 -43400.0 -0.12 -0.6333 -0.8061 3186513 PK04_094095 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E16 compound treatment 451970.0 -272000.0 -0.73 546590.0 18700.0 0.05 -0.4783 -0.6557 3068069 PK04_094096 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E17 mock treatment 592190.0 -132000.0 -0.35 433640.0 -94300.0 -0.26 -0.4327 -0.9883 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E18 mock treatment 760900.0 36500.0 0.1 478670.0 -49200.0 -0.14 -0.0267 -0.1601 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E19 compound treatment 552120.0 -172000.0 -0.46 558400.0 30500.0 0.08 -0.2662 -0.5692 3186514 PK04_094097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E20 compound treatment 250790.0 -474000.0 -1.27 338630.0 -189000.0 -0.52 -1.262 -0.9228 3186515 PK04_094098 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E21 compound treatment 273960.0 -450000.0 -1.2 332240.0 -196000.0 -0.54 -1.2306 -0.934 3068070 PK04_094099 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E22 compound treatment 365830.0 -359000.0 -0.96 271520.0 -256000.0 -0.7 -1.175 -0.9885 3186516 PK04_094100 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E23 compound treatment 322330.0 -402000.0 -1.07 463220.0 -64700.0 -0.18 -0.885 -0.813 3068071 PK04_094101 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 E24 compound treatment 255200.0 -469000.0 -1.25 314660.0 -213000.0 -0.59 -1.3002 -0.9399 3186517 PK04_094102 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F01 mock treatment 966330.0 242000.0 0.65 577930.0 50000.0 0.14 0.554 0.8386 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F02 mock treatment 887840.0 163000.0 0.44 648850.0 121000.0 0.33 0.5434 0.9909 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F03 compound treatment 627520.0 -96900.0 -0.26 443040.0 -84900.0 -0.23 -0.3478 -0.9986 3068072 PK04_094103 CN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F04 compound treatment 391420.0 -333000.0 -0.89 306090.0 -222000.0 -0.61 -1.0595 -0.9829 3000813 PK04_094104 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F05 compound treatment 558720.0 -166000.0 -0.44 456190.0 -71700.0 -0.2 -0.4522 -0.9335 3186518 PK04_094105 CN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F06 compound treatment 154560.0 -570000.0 -1.52 158300.0 -370000.0 -1.01 -1.7938 -0.9806 3000814 PK04_094106 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F07 compound treatment 392970.0 -331000.0 -0.89 294630.0 -233000.0 -0.64 -1.0789 -0.9874 3186519 PK04_094107 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F08 compound treatment 403970.0 -320000.0 -0.86 289230.0 -239000.0 -0.66 -1.0686 -0.9913 3089667 PK04_094108 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F09 mock treatment 917440.0 193000.0 0.52 453020.0 -74900.0 -0.21 0.2192 0.3949 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F10 mock treatment 565960.0 -158000.0 -0.42 784330.0 256000.0 0.7 0.1985 0.2417 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F11 compound treatment 338080.0 -386000.0 -1.03 237190.0 -291000.0 -0.8 -1.294 -0.9919 3068073 PK04_094109 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F12 compound treatment 325890.0 -399000.0 -1.06 553040.0 25100.0 0.07 -0.7039 -0.6599 3089654 PK04_094110 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F13 compound treatment 307470.0 -417000.0 -1.11 234590.0 -293000.0 -0.81 -1.3569 -0.9873 3186520 PK04_094111 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F14 compound treatment 207360.0 -517000.0 -1.38 151140.0 -377000.0 -1.03 -1.708 -0.9899 3089708 PK04_094112 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F15 compound treatment 288210.0 -436000.0 -1.17 194280.0 -334000.0 -0.92 -1.4715 -0.9929 3186521 PK04_094113 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F16 compound treatment 287360.0 -437000.0 -1.17 262430.0 -265000.0 -0.73 -1.3408 -0.9743 3000817 PK04_094114 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F17 mock treatment 827750.0 103000.0 0.28 182850.0 -345000.0 -0.95 -0.4747 -0.4811 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F18 mock treatment 417830.0 -307000.0 -0.82 606080.0 78200.0 0.21 -0.4273 -0.5048 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F19 compound treatment 290240.0 -434000.0 -1.16 323040.0 -205000.0 -0.56 -1.2177 -0.9448 3068074 PK04_094115 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F20 compound treatment 263220.0 -461000.0 -1.23 213920.0 -314000.0 -0.86 -1.4806 -0.9848 3089709 PK04_094116 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F21 compound treatment 362890.0 -362000.0 -0.97 312580.0 -215000.0 -0.59 -1.1008 -0.9723 3186522 PK04_094117 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(Cc5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F22 compound treatment 297640.0 -427000.0 -1.14 241440.0 -286000.0 -0.79 -1.3622 -0.9836 3000821 PK04_094118 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F23 compound treatment 454530.0 -270000.0 -0.72 350600.0 -177000.0 -0.49 -0.8539 -0.9817 3186523 PK04_094119 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 F24 compound treatment 378720.0 -346000.0 -0.92 371520.0 -156000.0 -0.43 -0.9565 -0.9393 3089711 PK04_094120 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G01 compound treatment 523250.0 -201000.0 -0.54 437160.0 -90800.0 -0.25 -0.5561 -0.939 3068075 PK04_094121 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G02 compound treatment 681040.0 -43400.0 -0.12 647720.0 120000.0 0.33 0.1507 0.4321 3186524 PK04_094122 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G03 mock treatment 891580.0 167000.0 0.45 631810.0 104000.0 0.29 0.5174 0.9766 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G04 mock treatment 927070.0 203000.0 0.54 251390.0 -277000.0 -0.76 -0.1541 -0.1652 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G05 compound treatment 828890.0 104000.0 0.28 271590.0 -256000.0 -0.7 -0.3003 -0.3966 3186575 PK04_094123 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G06 compound treatment 290420.0 -434000.0 -1.16 468360.0 -59600.0 -0.16 -0.9353 -0.7989 3186576 PK04_094124 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G07 compound treatment 619710.0 -105000.0 -0.28 263940.0 -264000.0 -0.72 -0.7102 -0.9142 3068110 PK04_094125 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G08 compound treatment 353800.0 -371000.0 -0.99 388720.0 -139000.0 -0.38 -0.9702 -0.9143 3186577 PK04_094126 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G09 compound treatment 358720.0 -366000.0 -0.98 221320.0 -307000.0 -0.84 -1.2859 -0.9973 3068111 PK04_094127 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G10 compound treatment 354910.0 -369000.0 -0.99 661930.0 134000.0 0.37 -0.4377 -0.4156 3186578 PK04_094128 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G11 compound treatment 727780.0 3370.0 0.01 794160.0 266000.0 0.73 0.5232 0.7158 3186579 PK04_094129 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G12 compound treatment 505330.0 -219000.0 -0.59 305240.0 -223000.0 -0.61 -0.8461 -0.9998 3068112 PK04_094130 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G13 compound treatment 242800.0 -482000.0 -1.29 406080.0 -122000.0 -0.33 -1.1461 -0.8623 3186580 PK04_094131 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCCN3CCOCC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G14 compound treatment 333760.0 -391000.0 -1.04 391480.0 -136000.0 -0.37 -1.0027 -0.9044 3186581 PK04_094132 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G15 compound treatment 477850.0 -247000.0 -0.66 326840.0 -201000.0 -0.55 -0.856 -0.9962 3068113 PK04_094133 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G16 compound treatment 249760.0 -475000.0 -1.27 200710.0 -327000.0 -0.9 -1.5317 -0.9858 3186582 PK04_094134 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G17 compound treatment 505620.0 -219000.0 -0.58 197040.0 -331000.0 -0.91 -1.0556 -0.9772 3186583 PK04_094135 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G18 compound treatment 490460.0 -234000.0 -0.62 310840.0 -217000.0 -0.6 -0.8633 -0.9997 3068114 PK04_094136 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G19 mock treatment 544920.0 -179000.0 -0.48 302120.0 -226000.0 -0.62 -0.7773 -0.9919 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G20 mock treatment 652060.0 -72300.0 -0.19 355380.0 -173000.0 -0.47 -0.4716 -0.9218 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G21 compound treatment 384320.0 -340000.0 -0.91 348750.0 -179000.0 -0.49 -0.9901 -0.9585 3186584 PK04_094137 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G22 compound treatment 409000.0 -315000.0 -0.84 423530.0 -104000.0 -0.29 -0.7983 -0.8972 3068115 PK04_094138 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G23 compound treatment 322600.0 -402000.0 -1.07 415520.0 -112000.0 -0.31 -0.9771 -0.875 3186585 PK04_094139 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 G24 compound treatment 438990.0 -285000.0 -0.76 381280.0 -147000.0 -0.4 -0.8237 -0.9555 3186586 PK04_094140 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H01 compound treatment 330770.0 -394000.0 -1.05 350120.0 -178000.0 -0.49 -1.0886 -0.9391 3068116 PK04_094141 CCCN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H02 compound treatment 682880.0 -41500.0 -0.11 225640.0 -302000.0 -0.83 -0.6652 -0.7945 3000914 PK04_094142 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H03 mock treatment 844670.0 120000.0 0.32 430950.0 -97000.0 -0.27 0.0389 0.0932 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H04 mock treatment 863370.0 139000.0 0.37 520920.0 -7000.0 -0.02 0.2489 0.6696 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H05 compound treatment 568190.0 -156000.0 -0.42 337600.0 -190000.0 -0.52 -0.6645 -0.9938 3068117 PK04_094143 CCCN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H06 compound treatment 237510.0 -487000.0 -1.3 288160.0 -240000.0 -0.66 -1.385 -0.9502 3089723 PK04_094144 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H07 compound treatment 358150.0 -366000.0 -0.98 318880.0 -209000.0 -0.57 -1.0975 -0.9677 3186589 PK04_094145 CN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H08 compound treatment 460400.0 -264000.0 -0.71 266580.0 -261000.0 -0.72 -1.006 -1.0 3089724 PK04_094146 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H09 compound treatment 528640.0 -196000.0 -0.52 378400.0 -150000.0 -0.41 -0.66 -0.9928 3186590 PK04_094147 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(C(=O)c5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H10 compound treatment 261930.0 -462000.0 -1.24 200320.0 -328000.0 -0.9 -1.5094 -0.9878 3000917 PK04_094148 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H11 compound treatment 297790.0 -427000.0 -1.14 194110.0 -334000.0 -0.92 -1.4538 -0.9942 3068119 PK04_094149 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H12 compound treatment 171960.0 -552000.0 -1.48 235730.0 -292000.0 -0.8 -1.6106 -0.959 3089768 PK04_094150 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H13 compound treatment 441360.0 -283000.0 -0.76 269280.0 -259000.0 -0.71 -1.0367 -0.9995 3186593 PK04_094151 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H14 compound treatment 323800.0 -401000.0 -1.07 588960.0 61000.0 0.17 -0.6381 -0.5892 3089763 PK04_094152 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H15 compound treatment 337120.0 -387000.0 -1.03 282350.0 -246000.0 -0.67 -1.2082 -0.9785 3186594 PK04_094153 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H16 compound treatment 222560.0 -502000.0 -1.34 204910.0 -323000.0 -0.89 -1.5749 -0.9799 3089764 PK04_094154 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H17 compound treatment 650930.0 -73500.0 -0.2 610260.0 82300.0 0.23 0.0211 0.0704 3068121 PK04_094155 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(C(=O)c5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H18 compound treatment 368500.0 -356000.0 -0.95 234040.0 -294000.0 -0.81 -1.2427 -0.9967 3000919 PK04_094156 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H19 mock treatment 621640.0 -103000.0 -0.27 555540.0 27600.0 0.08 -0.1405 -0.4933 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H20 mock treatment 834130.0 110000.0 0.29 875570.0 348000.0 0.95 0.8821 0.8835 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H21 compound treatment 656960.0 -67400.0 -0.18 301040.0 -227000.0 -0.62 -0.5678 -0.8757 3068122 PK04_094157 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H22 compound treatment 326030.0 -398000.0 -1.06 291910.0 -236000.0 -0.65 -1.2106 -0.9717 3089766 PK04_094158 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H23 compound treatment 336400.0 -388000.0 -1.04 351360.0 -177000.0 -0.48 -1.0756 -0.9401 3068123 PK04_094159 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 H24 compound treatment 364090.0 -360000.0 -0.96 267930.0 -260000.0 -0.71 -1.1852 -0.9892 3089769 PK04_094160 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I01 compound treatment 368270.0 -356000.0 -0.95 355120.0 -173000.0 -0.47 -1.0081 -0.9484 3186651 PK04_094161 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I02 compound treatment 445070.0 -279000.0 -0.75 698560.0 171000.0 0.47 -0.1963 -0.2228 3068124 PK04_094162 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I03 compound treatment 302410.0 -422000.0 -1.13 470610.0 -57300.0 -0.16 -0.9083 -0.7981 3186652 PK04_094163 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I04 compound treatment 635440.0 -89000.0 -0.24 389280.0 -139000.0 -0.38 -0.4372 -0.9743 3068125 PK04_094164 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I05 mock treatment 584410.0 -140000.0 -0.37 305760.0 -222000.0 -0.61 -0.6957 -0.9724 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I06 mock treatment 376220.0 -348000.0 -0.93 646330.0 118000.0 0.33 -0.4277 -0.4342 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I07 compound treatment 806880.0 82500.0 0.22 419130.0 -109000.0 -0.3 -0.0554 -0.1493 3186653 PK04_094165 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I08 compound treatment 638960.0 -85400.0 -0.23 828420.0 301000.0 0.83 0.422 0.493 3068126 PK04_094166 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I09 compound treatment 300090.0 -424000.0 -1.13 327210.0 -201000.0 -0.55 -1.191 -0.9451 3186654 PK04_094167 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I10 compound treatment 333660.0 -391000.0 -1.04 168560.0 -359000.0 -0.99 -1.4356 -0.9996 3068572 PK04_094168 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I11 compound treatment 263110.0 -461000.0 -1.23 182420.0 -345000.0 -0.95 -1.542 -0.9917 3186655 PK04_094169 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I12 compound treatment 295370.0 -429000.0 -1.15 195950.0 -332000.0 -0.91 -1.4548 -0.9936 3186656 PK04_094170 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I13 compound treatment 174130.0 -550000.0 -1.47 153250.0 -375000.0 -1.03 -1.7666 -0.9848 3068573 PK04_094171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I14 compound treatment 313340.0 -411000.0 -1.1 284900.0 -243000.0 -0.67 -1.2481 -0.9715 3186657 PK04_094172 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I15 compound treatment 299250.0 -425000.0 -1.14 441380.0 -86500.0 -0.24 -0.971 -0.8369 3068574 PK04_094173 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I16 compound treatment 213150.0 -511000.0 -1.37 347170.0 -181000.0 -0.5 -1.3165 -0.9061 3186658 PK04_094174 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I17 compound treatment 279110.0 -445000.0 -1.19 324290.0 -204000.0 -0.56 -1.2363 -0.9407 3186659 PK04_094175 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I18 compound treatment 320410.0 -404000.0 -1.08 242180.0 -286000.0 -0.78 -1.3177 -0.9877 3068575 PK04_094176 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I19 compound treatment 419200.0 -305000.0 -0.82 544660.0 16700.0 0.05 -0.5439 -0.6662 3186660 PK04_094177 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I20 compound treatment 329670.0 -395000.0 -1.05 302130.0 -226000.0 -0.62 -1.1839 -0.9679 3068577 PK04_094178 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I21 mock treatment 655260.0 -69100.0 -0.18 343400.0 -185000.0 -0.51 -0.4888 -0.9065 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I22 mock treatment 922770.0 198000.0 0.53 670440.0 143000.0 0.39 0.6513 0.9889 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I23 compound treatment 378660.0 -346000.0 -0.92 464090.0 -63800.0 -0.18 -0.7769 -0.8265 3186661 PK04_094179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 I24 compound treatment 232180.0 -492000.0 -1.31 284380.0 -244000.0 -0.67 -1.4024 -0.9508 3186662 PK04_094180 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J01 compound treatment 466270.0 -258000.0 -0.69 316730.0 -211000.0 -0.58 -0.8975 -0.9963 3068611 PK04_094181 CN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J02 compound treatment 289070.0 -435000.0 -1.16 406970.0 -121000.0 -0.33 -1.057 -0.8741 3089770 PK04_094182 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J03 compound treatment 600520.0 -124000.0 -0.33 311460.0 -216000.0 -0.59 -0.6542 -0.9618 3068612 PK04_094183 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J04 compound treatment 399110.0 -325000.0 -0.87 273570.0 -254000.0 -0.7 -1.1081 -0.9941 3001007 PK04_094184 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J05 mock treatment 249380.0 -475000.0 -1.27 752550.0 225000.0 0.62 -0.4611 -0.3268 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J06 mock treatment 837830.0 113000.0 0.3 500970.0 -26900.0 -0.07 0.1619 0.5192 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J07 compound treatment 364650.0 -360000.0 -0.96 309150.0 -219000.0 -0.6 -1.1042 -0.9744 3186665 PK04_094185 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J08 compound treatment 344120.0 -380000.0 -1.02 304550.0 -223000.0 -0.61 -1.1519 -0.9708 3089771 PK04_094186 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J09 compound treatment 280340.0 -444000.0 -1.19 252680.0 -275000.0 -0.76 -1.373 -0.9763 3186666 PK04_094187 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J10 compound treatment 346790.0 -378000.0 -1.01 334450.0 -193000.0 -0.53 -1.0888 -0.9551 3089776 PK04_094188 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J11 compound treatment 219140.0 -505000.0 -1.35 472120.0 -55800.0 -0.15 -1.0626 -0.7823 3068615 PK04_094189 CCCN1C(=O)[C@]2(COC(=N2)c3ccc(OCCCO)cc3)Cc4ccccc14 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J12 compound treatment 403120.0 -321000.0 -0.86 329280.0 -199000.0 -0.55 -0.9924 -0.9761 3001011 PK04_094190 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J13 compound treatment 318640.0 -406000.0 -1.08 294900.0 -233000.0 -0.64 -1.2187 -0.9684 3068616 PK04_094191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J14 compound treatment 314080.0 -410000.0 -1.1 286760.0 -241000.0 -0.66 -1.2431 -0.9709 3089772 PK04_094192 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J15 compound treatment 314350.0 -410000.0 -1.1 374400.0 -154000.0 -0.42 -1.0725 -0.9139 3068617 PK04_094193 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J16 compound treatment 387840.0 -337000.0 -0.9 237870.0 -290000.0 -0.8 -1.1987 -0.9982 3089773 PK04_094194 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J17 compound treatment 339950.0 -384000.0 -1.03 262800.0 -265000.0 -0.73 -1.2408 -0.9858 3186732 PK04_094195 CN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J18 compound treatment 370320.0 -354000.0 -0.95 301710.0 -226000.0 -0.62 -1.1079 -0.9792 3089774 PK04_094196 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J19 compound treatment 241630.0 -483000.0 -1.29 373600.0 -154000.0 -0.42 -1.2114 -0.8925 3186733 PK04_094197 CCCN1C(=O)[C@@]2(Cc3ccccc13)N=C(O[C@H]2c4ccccc4)c5ccc(OCCCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J20 compound treatment 390690.0 -334000.0 -0.89 282270.0 -246000.0 -0.67 -1.1072 -0.9905 3089775 PK04_094198 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J21 mock treatment 325240.0 -399000.0 -1.07 557840.0 29900.0 0.08 -0.6958 -0.6507 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J22 mock treatment 789330.0 64900.0 0.17 537050.0 9130.0 0.03 0.1403 0.801 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J23 compound treatment 642510.0 -81900.0 -0.22 306580.0 -221000.0 -0.61 -0.5844 -0.9048 3068619 PK04_094199 COC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 J24 compound treatment 273690.0 -451000.0 -1.2 274450.0 -253000.0 -0.7 -1.3433 -0.9661 3089828 PK04_094200 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K01 compound treatment 204880.0 -520000.0 -1.39 250240.0 -278000.0 -0.76 -1.5203 -0.9602 3068620 PK04_094201 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K02 compound treatment 856100.0 132000.0 0.35 893600.0 366000.0 1.0 0.9586 0.9011 3186736 PK04_094202 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K03 compound treatment 890620.0 166000.0 0.44 245760.0 -282000.0 -0.77 -0.2338 -0.2619 3186737 PK04_094203 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K04 compound treatment 842290.0 118000.0 0.31 717060.0 189000.0 0.52 0.5898 0.9713 3068660 PK04_094204 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K05 compound treatment 481720.0 -243000.0 -0.65 298460.0 -229000.0 -0.63 -0.9038 -0.9999 3186738 PK04_094205 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K06 compound treatment 680900.0 -43500.0 -0.12 375560.0 -152000.0 -0.42 -0.3779 -0.8706 3068661 PK04_094206 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K07 mock treatment 680030.0 -44400.0 -0.12 445670.0 -82200.0 -0.23 -0.2435 -0.9547 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K08 mock treatment 1014190.0 290000.0 0.77 440090.0 -87800.0 -0.24 0.3768 0.4648 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K09 compound treatment 520320.0 -204000.0 -0.55 830560.0 303000.0 0.83 0.2021 0.2033 3186739 PK04_094207 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K10 compound treatment 485990.0 -238000.0 -0.64 696700.0 169000.0 0.46 -0.1226 -0.1557 3186740 PK04_094208 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K11 compound treatment 225460.0 -499000.0 -1.33 480960.0 -47000.0 -0.13 -1.0335 -0.7719 3068664 PK04_094209 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K12 compound treatment 254590.0 -470000.0 -1.25 439770.0 -88100.0 -0.24 -1.0585 -0.8282 3186741 PK04_094210 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K13 compound treatment 342400.0 -382000.0 -1.02 386910.0 -141000.0 -0.39 -0.9952 -0.912 3068666 PK04_094211 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K14 compound treatment 264700.0 -460000.0 -1.23 298890.0 -229000.0 -0.63 -1.3128 -0.9517 3186742 PK04_094212 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K15 mock treatment 1000610.0 276000.0 0.74 339570.0 -188000.0 -0.52 0.156 0.1732 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K16 mock treatment 925240.0 201000.0 0.54 410080.0 -118000.0 -0.32 0.1505 0.2403 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K17 compound treatment 552800.0 -172000.0 -0.46 285940.0 -242000.0 -0.66 -0.7939 -0.9836 3186743 PK04_094213 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K18 compound treatment 343930.0 -380000.0 -1.02 345600.0 -182000.0 -0.5 -1.0725 -0.9468 3068667 PK04_094214 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K19 compound treatment 599080.0 -125000.0 -0.33 513120.0 -14800.0 -0.04 -0.2654 -0.7872 3186744 PK04_094215 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K20 compound treatment 307360.0 -417000.0 -1.11 304730.0 -223000.0 -0.61 -1.2209 -0.9604 3186745 PK04_094216 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K21 compound treatment 261360.0 -463000.0 -1.24 363330.0 -165000.0 -0.45 -1.1941 -0.9068 3068668 PK04_094217 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K22 compound treatment 413850.0 -311000.0 -0.83 426400.0 -102000.0 -0.28 -0.7836 -0.8955 3186746 PK04_094218 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K23 mock treatment 676520.0 -47900.0 -0.13 491450.0 -36500.0 -0.1 -0.1612 -0.9927 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 K24 mock treatment 506110.0 -218000.0 -0.58 600070.0 72200.0 0.2 -0.2722 -0.4421 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L01 compound treatment 884240.0 160000.0 0.43 691420.0 164000.0 0.45 0.6193 0.9997 3068669 PK04_094219 CCOC(=O)N1C(N=C(N1C(=O)OCC)c2ccc(OCCCO)cc2)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L02 compound treatment 325350.0 -399000.0 -1.07 436160.0 -91800.0 -0.25 -0.9318 -0.8508 3001020 PK04_094220 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L03 compound treatment 575940.0 -148000.0 -0.4 480380.0 -47500.0 -0.13 -0.3727 -0.8927 3068670 PK04_094221 COCCCNC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L04 compound treatment 192640.0 -532000.0 -1.42 407780.0 -120000.0 -0.33 -1.2376 -0.8487 3089829 PK04_094222 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L05 compound treatment 560100.0 -164000.0 -0.44 722770.0 195000.0 0.53 0.0679 0.0982 3186813 PK04_094223 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L06 compound treatment 332380.0 -392000.0 -1.05 236320.0 -292000.0 -0.8 -1.3065 -0.9912 3001022 PK04_094224 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L07 mock treatment 948160.0 224000.0 0.6 406500.0 -121000.0 -0.33 0.1869 0.2731 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L08 mock treatment 397370.0 -327000.0 -0.87 405050.0 -123000.0 -0.34 -0.8562 -0.9144 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L09 compound treatment 468990.0 -255000.0 -0.68 863700.0 336000.0 0.92 0.1695 0.1478 3067926 PK04_094225 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L10 compound treatment 581350.0 -143000.0 -0.38 346400.0 -182000.0 -0.5 -0.6226 -0.9914 3089768 PK04_094226 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L11 compound treatment 698920.0 -25500.0 -0.07 320930.0 -207000.0 -0.57 -0.45 -0.7862 3186815 PK04_094227 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L12 compound treatment 246030.0 -478000.0 -1.28 129400.0 -399000.0 -1.09 -1.6771 -0.997 3089830 PK04_094228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L13 compound treatment 743530.0 19100.0 0.05 245650.0 -282000.0 -0.77 -0.5119 -0.6591 3067927 PK04_094229 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L14 compound treatment 301310.0 -423000.0 -1.13 258370.0 -270000.0 -0.74 -1.3224 -0.9789 3089831 PK04_094230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L15 mock treatment 642960.0 -81400.0 -0.22 405520.0 -122000.0 -0.34 -0.3914 -0.9778 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L16 mock treatment 913120.0 189000.0 0.5 612390.0 84500.0 0.23 0.5204 0.9379 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L17 compound treatment 318640.0 -406000.0 -1.08 298010.0 -230000.0 -0.63 -1.2127 -0.9669 3067928 PK04_094231 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L18 compound treatment 411840.0 -313000.0 -0.83 604130.0 76200.0 0.21 -0.4424 -0.514 3001180 PK04_094232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L19 compound treatment 829170.0 105000.0 0.28 519960.0 -7960.0 -0.02 0.1824 0.6499 3067929 PK04_094233 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L20 compound treatment 309280.0 -415000.0 -1.11 269940.0 -258000.0 -0.71 -1.2849 -0.9766 3001092 PK04_094234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L21 compound treatment 605970.0 -118000.0 -0.32 485720.0 -42200.0 -0.12 -0.3056 -0.9071 3067930 PK04_094235 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L22 compound treatment 406720.0 -318000.0 -0.85 375970.0 -152000.0 -0.42 -0.895 -0.9465 3001093 PK04_094236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L23 mock treatment 715570.0 -8840.0 -0.02 715800.0 188000.0 0.52 0.348 0.674 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 L24 mock treatment 466400.0 -258000.0 -0.69 588370.0 60500.0 0.17 -0.3699 -0.5219 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M01 compound treatment 315330.0 -409000.0 -1.09 287870.0 -240000.0 -0.66 -1.2386 -0.9707 3067931 PK04_094237 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M02 compound treatment 758300.0 33900.0 0.09 850510.0 323000.0 0.89 0.6903 0.7753 3186821 PK04_094238 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M03 compound treatment 651200.0 -73200.0 -0.2 317350.0 -211000.0 -0.58 -0.547 -0.8964 3067933 PK04_094239 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M04 compound treatment 573210.0 -151000.0 -0.4 624690.0 96800.0 0.27 -0.0977 -0.2021 3186822 PK04_094240 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCCN3CCOCC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M05 compound treatment 322320.0 -402000.0 -1.07 505090.0 -22800.0 -0.06 -0.8037 -0.7471 3067934 PK04_094241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M06 compound treatment 865440.0 141000.0 0.38 734410.0 206000.0 0.57 0.6672 0.9803 3186823 PK04_094242 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M07 compound treatment 324280.0 -400000.0 -1.07 324000.0 -204000.0 -0.56 -1.1516 -0.9545 3186824 PK04_094243 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M08 compound treatment 219710.0 -505000.0 -1.35 185280.0 -343000.0 -0.94 -1.6184 -0.9845 3186825 PK04_094244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M09 mock treatment 987520.0 263000.0 0.7 850820.0 323000.0 0.89 1.1238 0.9934 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M10 mock treatment 877830.0 153000.0 0.41 637630.0 110000.0 0.3 0.5028 0.9885 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M11 compound treatment 178960.0 -545000.0 -1.46 229800.0 -298000.0 -0.82 -1.6089 -0.9628 3067981 PK04_094245 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M12 compound treatment 700270.0 -24100.0 -0.06 305390.0 -223000.0 -0.61 -0.4776 -0.7774 3186826 PK04_094246 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M13 mock treatment 739690.0 15300.0 0.04 358720.0 -169000.0 -0.46 -0.2996 -0.6425 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M14 mock treatment 846780.0 122000.0 0.33 603800.0 75900.0 0.21 0.3784 0.9763 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M15 compound treatment 289990.0 -434000.0 -1.16 338120.0 -190000.0 -0.52 -1.1889 -0.9347 3067982 PK04_094247 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M16 compound treatment 390730.0 -334000.0 -0.89 262590.0 -265000.0 -0.73 -1.1453 -0.995 3186827 PK04_094248 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M17 compound treatment 246080.0 -478000.0 -1.28 331300.0 -197000.0 -0.54 -1.2851 -0.9266 3067983 PK04_094249 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M18 compound treatment 606240.0 -118000.0 -0.32 267680.0 -260000.0 -0.71 -0.7284 -0.9325 3186828 PK04_094250 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M19 compound treatment 603860.0 -121000.0 -0.32 374400.0 -154000.0 -0.42 -0.5257 -0.9912 3186829 PK04_094251 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M20 compound treatment 750930.0 26500.0 0.07 641780.0 114000.0 0.31 0.2711 0.8459 3067984 PK04_094252 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M21 compound treatment 449940.0 -274000.0 -0.73 606190.0 78300.0 0.21 -0.3664 -0.4797 3186907 PK04_094253 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M22 compound treatment 475750.0 -249000.0 -0.66 582880.0 55000.0 0.15 -0.3629 -0.5329 3067985 PK04_094254 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M23 compound treatment 386240.0 -338000.0 -0.9 303160.0 -225000.0 -0.62 -1.075 -0.9827 3186908 PK04_094255 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 M24 compound treatment 312320.0 -412000.0 -1.1 509120.0 -18800.0 -0.05 -0.8148 -0.7395 3186909 PK04_094256 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N01 compound treatment 851900.0 127000.0 0.34 864000.0 336000.0 0.92 0.8932 0.9082 3067986 PK04_094257 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N02 compound treatment 428420.0 -296000.0 -0.79 523780.0 -4140.0 -0.01 -0.5671 -0.7172 3186910 PK04_094258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N03 compound treatment 858930.0 135000.0 0.36 598350.0 70400.0 0.19 0.3908 0.9578 3067987 PK04_094259 CN(C)C(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N04 compound treatment 887380.0 163000.0 0.44 644820.0 117000.0 0.32 0.5347 0.9888 3186911 PK04_094260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N05 compound treatment 641240.0 -83200.0 -0.22 390650.0 -137000.0 -0.38 -0.4236 -0.9682 3414052 PK04_094261 COC(=O)[C@@H]1N=C(O[C@@H]1C)c2ccc(OCCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N06 compound treatment 939360.0 215000.0 0.57 912590.0 385000.0 1.06 1.1527 0.959 3186912 PK04_094262 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N07 compound treatment 677500.0 -46900.0 -0.13 742840.0 215000.0 0.59 0.3286 0.5448 3186913 PK04_094263 OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N08 compound treatment 836810.0 112000.0 0.3 587250.0 59300.0 0.16 0.3275 0.9587 1952953 PK04_094264 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N09 mock treatment 898350.0 174000.0 0.46 929950.0 402000.0 1.1 1.109 0.9261 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N10 mock treatment 827780.0 103000.0 0.28 920380.0 392000.0 1.08 0.9571 0.8605 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N11 compound treatment 882560.0 158000.0 0.42 658210.0 130000.0 0.36 0.5516 0.9966 3068027 PK04_094265 CC(=O)OC[C@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N12 compound treatment 596760.0 -128000.0 -0.34 441240.0 -86700.0 -0.24 -0.4094 -0.9845 3186914 PK04_094266 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N13 mock treatment 1001980.0 278000.0 0.74 435970.0 -91900.0 -0.25 0.3457 0.4415 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N14 mock treatment 924240.0 200000.0 0.53 345370.0 -183000.0 -0.5 0.023 0.0315 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N15 compound treatment 934620.0 210000.0 0.56 761920.0 234000.0 0.64 0.8513 0.9977 3068028 PK04_094267 CC(=O)OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N16 compound treatment 869980.0 146000.0 0.39 682960.0 155000.0 0.43 0.5759 0.999 3186915 PK04_094268 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N17 compound treatment 961920.0 238000.0 0.63 507390.0 -20500.0 -0.06 0.4087 0.6418 3068029 PK04_094269 CC(=O)OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N18 compound treatment 371380.0 -353000.0 -0.94 538850.0 10900.0 0.03 -0.6455 -0.6843 1952947 PK04_094270 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@@H](Cc5ccccc5)C/C=C/C[C@H](Cc6ccccc6)C(=O)O[C@@H]14 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N19 compound treatment 800010.0 75600.0 0.2 564640.0 36700.0 0.1 0.2141 0.9485 3068030 PK04_094271 OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N20 compound treatment 303320.0 -421000.0 -1.12 614740.0 86800.0 0.24 -0.6267 -0.5451 3186916 PK04_094272 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N21 compound treatment 766830.0 42400.0 0.11 379590.0 -148000.0 -0.41 -0.2078 -0.4917 3068031 PK04_094273 CC(=O)OC[C@@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N22 compound treatment 259230.0 -465000.0 -1.24 239540.0 -288000.0 -0.79 -1.4384 -0.9763 1952944 PK04_094274 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N23 compound treatment 534470.0 -190000.0 -0.51 557490.0 29600.0 0.08 -0.3013 -0.5865 3186917 PK04_094275 CC(=O)OC[C@H](C=C)N(Cc1ccc(cc1)[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 N24 compound treatment 546560.0 -178000.0 -0.48 515700.0 -12200.0 -0.03 -0.3596 -0.7552 3413982 PK04_094276 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O01 compound treatment 278980.0 -445000.0 -1.19 255560.0 -272000.0 -0.75 -1.37 -0.975 3068032 PK04_094277 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O02 compound treatment 527900.0 -197000.0 -0.52 331210.0 -197000.0 -0.54 -0.753 -0.9999 3186919 PK04_094278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O03 compound treatment 889130.0 165000.0 0.44 309180.0 -219000.0 -0.6 -0.1135 -0.1525 3068033 PK04_094279 NC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O04 compound treatment 600800.0 -124000.0 -0.33 495800.0 -32100.0 -0.09 -0.2958 -0.8656 3186920 PK04_094280 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O05 compound treatment 283580.0 -441000.0 -1.18 373330.0 -155000.0 -0.42 -1.1327 -0.905 3068035 PK04_094281 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O06 compound treatment 310930.0 -413000.0 -1.1 299150.0 -229000.0 -0.63 -1.225 -0.9642 3186921 PK04_094282 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O07 compound treatment 211280.0 -513000.0 -1.37 245980.0 -282000.0 -0.77 -1.5165 -0.9634 3186922 PK04_094283 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O08 compound treatment 279210.0 -445000.0 -1.19 700970.0 173000.0 0.48 -0.5049 -0.3943 3068037 PK04_094284 CN(C)C(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O09 compound treatment 411250.0 -313000.0 -0.84 433400.0 -94500.0 -0.26 -0.7749 -0.8849 3186923 PK04_094285 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O10 compound treatment 430260.0 -294000.0 -0.79 284180.0 -244000.0 -0.67 -1.0287 -0.9968 3068038 PK04_094286 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O11 mock treatment 530850.0 -194000.0 -0.52 785870.0 258000.0 0.71 0.1352 0.1542 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O12 mock treatment 352440.0 -372000.0 -0.99 290450.0 -237000.0 -0.65 -1.1635 -0.9791 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O13 compound treatment 555540.0 -169000.0 -0.45 482680.0 -45200.0 -0.12 -0.4068 -0.8695 3186924 PK04_094287 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O14 compound treatment 380580.0 -344000.0 -0.92 422150.0 -106000.0 -0.29 -0.8547 -0.8874 3186925 PK04_094288 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O15 compound treatment 513890.0 -211000.0 -0.56 696420.0 169000.0 0.46 -0.0705 -0.0968 3187013 PK04_094289 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O16 compound treatment 364020.0 -360000.0 -0.96 256440.0 -271000.0 -0.75 -1.2077 -0.992 3068077 PK04_094290 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O17 compound treatment 309330.0 -415000.0 -1.11 247710.0 -280000.0 -0.77 -1.3279 -0.9841 3187014 PK04_094291 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O18 compound treatment 298110.0 -426000.0 -1.14 258300.0 -270000.0 -0.74 -1.3285 -0.9782 3187015 PK04_094292 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O19 compound treatment 606150.0 -118000.0 -0.32 349280.0 -179000.0 -0.49 -0.5701 -0.9774 3068081 PK04_094293 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O20 compound treatment 234210.0 -490000.0 -1.31 217540.0 -310000.0 -0.85 -1.5284 -0.9784 3187016 PK04_094294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O21 compound treatment 343690.0 -381000.0 -1.02 256860.0 -271000.0 -0.74 -1.2453 -0.9882 3187017 PK04_094295 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O22 compound treatment 324640.0 -400000.0 -1.07 228510.0 -299000.0 -0.82 -1.3363 -0.9916 3068083 PK04_094296 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O23 compound treatment 269950.0 -454000.0 -1.21 152910.0 -375000.0 -1.03 -1.5863 -0.9966 3187018 PK04_094297 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 O24 compound treatment 223720.0 -501000.0 -1.34 311420.0 -216000.0 -0.59 -1.3659 -0.9333 3068084 PK04_094298 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P01 compound treatment 364710.0 -360000.0 -0.96 274780.0 -253000.0 -0.69 -1.1708 -0.9874 3187019 PK04_094299 CC(=O)OC[C@H](C=C)N(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P02 compound treatment 346470.0 -378000.0 -1.01 213570.0 -314000.0 -0.86 -1.324 -0.997 3413984 PK04_094300 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P03 compound treatment 455890.0 -269000.0 -0.72 297410.0 -231000.0 -0.63 -0.9546 -0.9981 3068086 PK04_094301 COc1ccc(CN([C@H](CO)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P04 compound treatment 263440.0 -461000.0 -1.23 248160.0 -280000.0 -0.77 -1.4137 -0.9742 3413986 PK04_094302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P05 compound treatment 238050.0 -486000.0 -1.3 296250.0 -232000.0 -0.64 -1.3683 -0.946 3068087 PK04_094303 COc1cc(CN([C@@H](COC(=O)C)C=C)S(=O)(=O)c2ccc(Br)cc2)ccc1OC(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P06 compound treatment 634020.0 -90400.0 -0.24 220280.0 -308000.0 -0.84 -0.7679 -0.8742 1952975 PK04_094304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P07 compound treatment 585200.0 -139000.0 -0.37 272640.0 -255000.0 -0.7 -0.7585 -0.956 3068088 PK04_094305 OCCCNS(=O)(=O)c1ccc(Br)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P08 compound treatment 374670.0 -350000.0 -0.93 195940.0 -332000.0 -0.91 -1.305 -0.9999 3413993 PK04_094306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P09 compound treatment 257020.0 -467000.0 -1.25 238240.0 -290000.0 -0.8 -1.4451 -0.9763 3068089 PK04_094307 CC[Si](CC)(CC)OC[C@@H](C=C)N(Cc1ccc(OC(=O)C)c(OC)c1)S(=O)(=O)c2ccc(Br)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P10 compound treatment 243920.0 -480000.0 -1.28 192000.0 -336000.0 -0.92 -1.5596 -0.9869 1952969 PK04_094308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5ccccc5)C/C=C/C[C@@H](Cc6ccccc6)C(=O)O[C@@H]14 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P11 mock treatment 301780.0 -423000.0 -1.13 295070.0 -233000.0 -0.64 -1.2502 -0.9637 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P12 mock treatment 386300.0 -338000.0 -0.9 236530.0 -291000.0 -0.8 -1.2042 -0.9982 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P13 compound treatment 364680.0 -360000.0 -0.96 265250.0 -263000.0 -0.72 -1.1893 -0.99 3068090 PK04_094309 COc1cc(CO)ccc1OC(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P14 compound treatment 313440.0 -411000.0 -1.1 416270.0 -112000.0 -0.31 -0.9929 -0.8712 3068091 PK04_094310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P15 compound treatment 293540.0 -431000.0 -1.15 456850.0 -71100.0 -0.2 -0.9517 -0.8154 3187025 PK04_094311 COc1ccc(CN(C2=CC[C@@]3(C(=O)N)C(=O)C(=C(Cl)C(=O)[C@]3(C2)C#N)Cl)S(=O)(=O)c4ccc(Br)cc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P16 compound treatment 392560.0 -332000.0 -0.89 270360.0 -258000.0 -0.71 -1.1267 -0.9937 3187026 PK04_094312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P17 compound treatment 418590.0 -306000.0 -0.82 254340.0 -274000.0 -0.75 -1.1087 -0.9991 3068092 PK04_094313 CC(C)(C)OC(=O)N1[C@H](COC1(C)C)C=C(Br)Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P18 compound treatment 242930.0 -481000.0 -1.29 216050.0 -312000.0 -0.86 -1.5148 -0.9805 3187027 PK04_094314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P19 compound treatment 329120.0 -395000.0 -1.06 378880.0 -149000.0 -0.41 -1.0359 -0.9148 1003211 PK04_094315 CNS(=O)(=O)c1ccc(C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P20 compound treatment 351960.0 -372000.0 -0.99 346570.0 -181000.0 -0.5 -1.0555 -0.9488 3187028 PK04_094316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P21 compound treatment 268270.0 -456000.0 -1.22 250400.0 -278000.0 -0.76 -1.4002 -0.9745 3068127 PK04_094317 COc1cc(COC(=O)C)ccc1OC(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P22 compound treatment 320000.0 -404000.0 -1.08 373440.0 -154000.0 -0.42 -1.0637 -0.9166 3187029 PK04_094318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P23 compound treatment 351110.0 -373000.0 -1.0 331150.0 -197000.0 -0.54 -1.087 -0.9586 3068129 PK04_094319 OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2094 P24 compound treatment 275630.0 -449000.0 -1.2 308800.0 -219000.0 -0.6 -1.273 -0.9492 3413981 PK04_094320 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A01 compound treatment 535710.0 -160000.0 -0.43 235570.0 -329000.0 -0.9 -0.9418 -0.9417 3067957 PK04_095001 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A02 compound treatment 584160.0 -112000.0 -0.3 433350.0 -131000.0 -0.36 -0.4663 -0.9956 3187176 PK04_095002 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A03 compound treatment 362980.0 -333000.0 -0.89 237960.0 -327000.0 -0.9 -1.2633 -1.0 3067577 PK04_095003 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A04 compound treatment 306770.0 -389000.0 -1.04 428750.0 -136000.0 -0.37 -0.9991 -0.9046 3187436 PK04_095004 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A05 compound treatment 377060.0 -319000.0 -0.85 452080.0 -113000.0 -0.31 -0.8211 -0.9061 3186425 PK04_095005 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6I)c7ccc(cc7)[N+](=O)[O-])cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A06 compound treatment 298020.0 -398000.0 -1.06 306130.0 -259000.0 -0.71 -1.2537 -0.9808 3187069 PK04_095006 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A07 compound treatment 742420.0 46500.0 0.12 472450.0 -92400.0 -0.25 -0.0915 -0.324 3187427 PK04_095007 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A08 compound treatment 228960.0 -467000.0 -1.25 255320.0 -309000.0 -0.85 -1.4828 -0.9825 3187515 PK04_095008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6)c7ccc(cc7)[N+](=O)[O-])cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A09 compound treatment 770560.0 74600.0 0.2 539170.0 -25600.0 -0.07 0.0912 0.4314 3187425 PK04_095009 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A10 compound treatment 742280.0 46400.0 0.12 608640.0 43800.0 0.12 0.1726 0.9999 3068592 PK04_095010 CCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A11 compound treatment 456130.0 -240000.0 -0.64 336830.0 -228000.0 -0.63 -0.8955 -0.9999 3187517 PK04_095011 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A12 compound treatment 733350.0 37400.0 0.1 403380.0 -161000.0 -0.44 -0.2427 -0.5342 3187344 PK04_095012 COCCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A13 mock treatment 591090.0 -105000.0 -0.28 519200.0 -45600.0 -0.13 -0.2865 -0.9341 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A14 mock treatment 369550.0 -326000.0 -0.87 399760.0 -165000.0 -0.45 -0.9368 -0.9535 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A15 compound treatment 760160.0 64200.0 0.17 608060.0 43300.0 0.12 0.2053 0.9839 3186552 PK04_095013 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A16 compound treatment 627170.0 -68800.0 -0.18 699590.0 135000.0 0.37 0.1318 0.319 3187439 PK04_095014 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A17 compound treatment 787920.0 92000.0 0.25 799040.0 234000.0 0.64 0.6285 0.9129 3187073 PK04_095015 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A18 compound treatment 448510.0 -247000.0 -0.66 607890.0 43100.0 0.12 -0.3837 -0.5715 3187272 PK04_095016 COCCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A19 compound treatment 461560.0 -234000.0 -0.63 300960.0 -264000.0 -0.72 -0.9549 -0.9974 3187508 PK04_095017 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NC3CC3)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A20 compound treatment 292930.0 -403000.0 -1.08 248480.0 -316000.0 -0.87 -1.3752 -0.9943 3186432 PK04_095018 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A21 compound treatment 346320.0 -350000.0 -0.93 511330.0 -53500.0 -0.15 -0.7641 -0.8083 3068646 PK04_095019 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A22 compound treatment 823310.0 127000.0 0.34 550080.0 -14700.0 -0.04 0.212 0.6187 3068651 PK04_095020 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A23 compound treatment 585080.0 -111000.0 -0.3 412800.0 -152000.0 -0.42 -0.5044 -0.9859 3187585 PK04_095021 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 A24 compound treatment 701500.0 5570.0 0.01 498240.0 -66600.0 -0.18 -0.1187 -0.6474 3187430 PK04_095022 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B01 compound treatment 283680.0 -412000.0 -1.1 292320.0 -272000.0 -0.75 -1.3076 -0.9823 3187519 PK04_095023 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B02 compound treatment 535680.0 -160000.0 -0.43 668980.0 104000.0 0.29 -0.1004 -0.1951 3186885 PK04_095024 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B03 compound treatment 894260.0 198000.0 0.53 800550.0 236000.0 0.65 0.8322 0.9951 3187435 PK04_095025 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B04 compound treatment 844670.0 149000.0 0.4 728480.0 164000.0 0.45 0.5987 0.9981 3186491 PK04_095026 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B05 compound treatment 762260.0 66300.0 0.18 387620.0 -177000.0 -0.49 -0.2187 -0.4224 3068539 PK04_095027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(F)cc(c4)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B06 compound treatment 588110.0 -108000.0 -0.29 729410.0 165000.0 0.45 0.1159 0.2163 3186559 PK04_095028 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B07 compound treatment 778290.0 82400.0 0.22 633820.0 69000.0 0.19 0.2895 0.9972 3068561 PK04_095029 CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B08 compound treatment 240360.0 -456000.0 -1.22 290490.0 -274000.0 -0.75 -1.393 -0.9734 3068322 PK04_095030 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B09 compound treatment 562720.0 -133000.0 -0.36 604270.0 39500.0 0.11 -0.175 -0.4705 3187432 PK04_095031 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B10 compound treatment 537280.0 -159000.0 -0.42 313660.0 -251000.0 -0.69 -0.7872 -0.9727 3068145 PK04_095032 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(F)(F)F)c5ccccc5C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B11 compound treatment 712760.0 16800.0 0.04 629280.0 64500.0 0.18 0.157 0.8594 3187265 PK04_095033 CC(C)N1[C@H]([C@H](C(=O)NCCCN(C)C)c2ccccc2C1=O)c3ccc(CO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B12 compound treatment 764930.0 69000.0 0.18 260610.0 -304000.0 -0.84 -0.4602 -0.5381 3186629 PK04_095034 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B13 mock treatment 804960.0 109000.0 0.29 367800.0 -197000.0 -0.54 -0.1765 -0.2874 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B14 mock treatment 743590.0 47700.0 0.13 431280.0 -134000.0 -0.37 -0.1692 -0.436 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B15 compound treatment 677930.0 -18000.0 -0.05 663810.0 99000.0 0.27 0.1582 0.5731 3187269 PK04_095035 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3CCCCC3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B16 compound treatment 555610.0 -140000.0 -0.37 494320.0 -70500.0 -0.19 -0.4019 -0.9527 3186887 PK04_095036 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B17 compound treatment 748410.0 52500.0 0.14 473180.0 -91600.0 -0.25 -0.0788 -0.2735 3068417 PK04_095037 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B18 compound treatment 786140.0 90200.0 0.24 525080.0 -39700.0 -0.11 0.0933 0.3526 3067610 PK04_095038 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(C7CC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B19 compound treatment 520760.0 -175000.0 -0.47 474180.0 -90600.0 -0.25 -0.5068 -0.9563 3068639 PK04_095039 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B20 compound treatment 563560.0 -132000.0 -0.35 436180.0 -129000.0 -0.35 -0.4997 -1.0 3068006 PK04_095040 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B21 compound treatment 754400.0 58500.0 0.16 580970.0 16200.0 0.04 0.1418 0.8735 3068601 PK04_095041 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCc4ccccc4)c5ccccc5C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B22 compound treatment 797290.0 101000.0 0.27 502450.0 -62400.0 -0.17 0.0704 0.2197 3068203 PK04_095042 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5Cl)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B23 compound treatment 478240.0 -218000.0 -0.58 471200.0 -93600.0 -0.26 -0.5929 -0.9326 3187355 PK04_095043 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCC(F)(F)F)c4ccccc4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 B24 compound treatment 844120.0 148000.0 0.4 658420.0 93600.0 0.26 0.4616 0.9781 3068156 PK04_095044 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C01 compound treatment 794760.0 98800.0 0.26 760070.0 195000.0 0.54 0.5657 0.9467 3187590 PK04_095045 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C02 compound treatment 608090.0 -87800.0 -0.23 655780.0 91000.0 0.25 0.0107 0.0313 3187180 PK04_095046 CC(C)NC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C03 compound treatment 674420.0 -21500.0 -0.06 313890.0 -251000.0 -0.69 -0.5277 -0.7634 3186493 PK04_095047 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C04 compound treatment 36180.0 -660000.0 -1.76 84000.0 -481000.0 -1.32 -2.1794 -0.9899 3186427 PK04_095048 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C05 compound treatment 629530.0 -66400.0 -0.18 408740.0 -156000.0 -0.43 -0.4284 -0.9238 3187172 PK04_095049 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C06 compound treatment 557780.0 -138000.0 -0.37 509510.0 -55300.0 -0.15 -0.3683 -0.923 3187080 PK04_095050 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C07 compound treatment 750840.0 54900.0 0.15 707630.0 143000.0 0.39 0.381 0.91 3186988 PK04_095051 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C08 compound treatment 270730.0 -425000.0 -1.14 256880.0 -308000.0 -0.85 -1.4008 -0.9894 3068011 PK04_095052 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C09 compound treatment 424000.0 -272000.0 -0.73 586570.0 21800.0 0.06 -0.4713 -0.6467 3068498 PK04_095053 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C10 compound treatment 147700.0 -548000.0 -1.46 118880.0 -446000.0 -1.22 -1.9011 -0.996 3186550 PK04_095054 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C11 mock treatment 441160.0 -255000.0 -0.68 601980.0 37200.0 0.1 -0.409 -0.5944 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C12 mock treatment 733560.0 37600.0 0.1 666980.0 102000.0 0.28 0.2694 0.9042 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C13 compound treatment 586950.0 -109000.0 -0.29 660260.0 95500.0 0.26 -0.0205 -0.0524 3187361 PK04_095055 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C14 compound treatment 560570.0 -135000.0 -0.36 474010.0 -90800.0 -0.25 -0.4319 -0.9835 3068504 PK04_095056 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C15 mock treatment 681030.0 -14900.0 -0.04 338740.0 -226000.0 -0.62 -0.467 -0.7509 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C16 mock treatment 728880.0 33000.0 0.09 305690.0 -259000.0 -0.71 -0.4408 -0.6149 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C17 compound treatment 326970.0 -369000.0 -0.99 246360.0 -318000.0 -0.87 -1.315 -0.9982 3067969 PK04_095057 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCCN(C)C)c3ccc(cc3)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C18 compound treatment 277060.0 -419000.0 -1.12 363720.0 -201000.0 -0.55 -1.1815 -0.947 3187359 PK04_095058 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C19 compound treatment 521670.0 -174000.0 -0.47 250440.0 -314000.0 -0.86 -0.9394 -0.958 3187087 PK04_095059 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C20 compound treatment 512130.0 -184000.0 -0.49 697320.0 133000.0 0.36 -0.0899 -0.1471 3187443 PK04_095060 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C21 compound treatment 243310.0 -453000.0 -1.21 251620.0 -313000.0 -0.86 -1.4628 -0.9861 3067571 PK04_095061 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C22 compound treatment 751790.0 55900.0 0.15 645880.0 81100.0 0.22 0.2629 0.9811 3187181 PK04_095062 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C23 compound treatment 366300.0 -330000.0 -0.88 359910.0 -205000.0 -0.56 -1.0203 -0.9766 3187509 PK04_095063 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)c4ccc(cc4)[N+](=O)[O-])cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 C24 compound treatment 493920.0 -202000.0 -0.54 440910.0 -124000.0 -0.34 -0.622 -0.9753 3068474 PK04_095064 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D01 compound treatment 488870.0 -207000.0 -0.55 748160.0 183000.0 0.5 -0.0351 -0.047 3068587 PK04_095065 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(CC3(CC4CC5CC(C4)C3)C5)C(=O)c6ccccc26)c7ccc(CO)cc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D02 compound treatment 286790.0 -409000.0 -1.09 297690.0 -267000.0 -0.73 -1.2913 -0.9812 3068318 PK04_095066 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D03 compound treatment 843050.0 147000.0 0.39 467920.0 -96900.0 -0.27 0.0898 0.1892 3187363 PK04_095067 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D04 compound treatment 777120.0 81200.0 0.22 489810.0 -75000.0 -0.21 0.0078 0.0259 3186486 PK04_095068 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CCN7CCOCC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D05 compound treatment 781560.0 85600.0 0.23 685480.0 121000.0 0.33 0.396 0.9836 3187179 PK04_095069 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(=O)c3ccccc23)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D06 compound treatment 313440.0 -382000.0 -1.02 310880.0 -254000.0 -0.7 -1.2153 -0.9826 3187522 PK04_095070 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D07 compound treatment 730330.0 34400.0 0.09 351380.0 -213000.0 -0.59 -0.3494 -0.589 3068515 PK04_095071 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D08 compound treatment 702670.0 6740.0 0.02 548800.0 -16000.0 -0.04 -0.0183 -0.3863 3186872 PK04_095072 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D09 compound treatment 411000.0 -285000.0 -0.76 334350.0 -230000.0 -0.63 -0.9855 -0.9958 3068609 PK04_095073 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D10 compound treatment 273970.0 -422000.0 -1.13 283610.0 -281000.0 -0.77 -1.3428 -0.983 3186795 PK04_095074 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D11 mock treatment 815310.0 119000.0 0.32 494940.0 -69900.0 -0.19 0.0898 0.2414 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D12 mock treatment 540910.0 -155000.0 -0.41 724980.0 160000.0 0.44 0.0182 0.0301 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D13 compound treatment 677470.0 -18500.0 -0.05 764870.0 200000.0 0.55 0.3535 0.6411 3067964 PK04_095075 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D14 compound treatment 670820.0 -25100.0 -0.07 727800.0 163000.0 0.45 0.269 0.5945 3068230 PK04_095076 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D15 mock treatment 702100.0 6170.0 0.02 809950.0 245000.0 0.67 0.4876 0.7242 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D16 mock treatment 396590.0 -299000.0 -0.8 497630.0 -67200.0 -0.18 -0.6958 -0.8479 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D17 compound treatment 763120.0 67200.0 0.18 731790.0 167000.0 0.46 0.4511 0.9162 3068595 PK04_095077 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCc3ccccc3)c4ccccc4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D18 compound treatment 612490.0 -83400.0 -0.22 374130.0 -191000.0 -0.52 -0.5278 -0.9276 3186982 PK04_095078 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D19 compound treatment 394100.0 -302000.0 -0.81 322140.0 -243000.0 -0.67 -1.0411 -0.9955 3187440 PK04_095079 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D20 compound treatment 390270.0 -306000.0 -0.82 441140.0 -124000.0 -0.34 -0.8174 -0.9244 3068415 PK04_095080 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D21 compound treatment 560040.0 -136000.0 -0.36 279360.0 -285000.0 -0.78 -0.8108 -0.9388 3068596 PK04_095081 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCC(F)(F)F)c3ccccc3C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D22 compound treatment 274290.0 -422000.0 -1.13 330500.0 -234000.0 -0.64 -1.2512 -0.9647 3186713 PK04_095082 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D23 compound treatment 666340.0 -29600.0 -0.08 620230.0 55400.0 0.15 0.0517 0.3016 3187357 PK04_095083 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 D24 compound treatment 252640.0 -443000.0 -1.18 282970.0 -282000.0 -0.77 -1.3844 -0.9787 3068270 PK04_095084 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCCN6CCOCC6)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E01 mock treatment 690600.0 -5330.0 -0.01 701180.0 136000.0 0.37 0.2547 0.6797 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E02 mock treatment 631290.0 -64600.0 -0.17 669650.0 105000.0 0.29 0.0815 0.2427 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E03 compound treatment 368690.0 -327000.0 -0.87 758080.0 193000.0 0.53 -0.2428 -0.2375 3068636 PK04_095085 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E04 compound treatment 795040.0 99100.0 0.26 459120.0 -106000.0 -0.29 -0.018 -0.0458 3186556 PK04_095086 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E05 compound treatment 753550.0 57600.0 0.15 222570.0 -342000.0 -0.94 -0.5556 -0.5835 3187587 PK04_095087 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E06 compound treatment 384930.0 -311000.0 -0.83 268360.0 -296000.0 -0.81 -1.1629 -0.9999 3186428 PK04_095088 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E07 compound treatment 385140.0 -311000.0 -0.83 705680.0 141000.0 0.39 -0.3135 -0.3423 3187266 PK04_095089 CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E08 compound treatment 746690.0 50800.0 0.14 436290.0 -129000.0 -0.35 -0.1536 -0.4064 3187351 PK04_095090 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E09 mock treatment 765500.0 69600.0 0.19 622580.0 57800.0 0.16 0.2436 0.9969 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E10 mock treatment 768930.0 73000.0 0.19 358890.0 -206000.0 -0.57 -0.2619 -0.4379 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E11 compound treatment 734190.0 38300.0 0.1 596640.0 31800.0 0.09 0.1341 0.997 3068004 PK04_095091 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E12 compound treatment 587140.0 -109000.0 -0.29 600480.0 35700.0 0.1 -0.1362 -0.4442 3186500 PK04_095092 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E13 compound treatment 770780.0 74900.0 0.2 426670.0 -138000.0 -0.38 -0.1268 -0.2958 3187346 PK04_095093 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCN3CCOCC3)c4ccccc4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E14 compound treatment 629390.0 -66500.0 -0.18 379040.0 -186000.0 -0.51 -0.4863 -0.9004 3187262 PK04_095094 CC(C)N1[C@H]([C@H](C(=O)NCCN2CCOCC2)c3ccccc3C1=O)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E15 compound treatment 398720.0 -297000.0 -0.79 230810.0 -334000.0 -0.92 -1.2097 -0.9974 3067574 PK04_095095 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E16 compound treatment 657030.0 -38900.0 -0.1 450630.0 -114000.0 -0.31 -0.2951 -0.8937 3187350 PK04_095096 COCCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E17 mock treatment 770020.0 74100.0 0.2 647930.0 83100.0 0.23 0.3013 0.9975 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E18 mock treatment 835900.0 140000.0 0.37 549410.0 -15400.0 -0.04 0.2345 0.6232 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E19 compound treatment 403600.0 -292000.0 -0.78 397390.0 -167000.0 -0.46 -0.8771 -0.9681 3068657 PK04_095097 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E20 compound treatment 425760.0 -270000.0 -0.72 401760.0 -163000.0 -0.45 -0.8268 -0.9736 3068140 PK04_095098 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E21 compound treatment 337400.0 -359000.0 -0.96 403070.0 -162000.0 -0.44 -0.9911 -0.939 3186562 PK04_095099 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E22 compound treatment 658050.0 -37900.0 -0.1 743370.0 179000.0 0.49 0.2751 0.5496 3187591 PK04_095100 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E23 compound treatment 743040.0 47100.0 0.13 377690.0 -187000.0 -0.51 -0.2743 -0.5186 3187263 PK04_095101 CC(C)N1[C@H]([C@H](C(=O)NCc2ccccc2)c3ccccc3C1=O)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 E24 compound treatment 474250.0 -222000.0 -0.59 456610.0 -108000.0 -0.3 -0.6287 -0.9491 3068517 PK04_095102 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F01 mock treatment 920160.0 224000.0 0.6 656260.0 91500.0 0.25 0.601 0.9255 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F02 mock treatment 891100.0 195000.0 0.52 826840.0 262000.0 0.72 0.8773 0.9875 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F03 compound treatment 768980.0 73100.0 0.2 577600.0 12800.0 0.04 0.1628 0.8212 3187079 PK04_095103 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F04 compound treatment 533800.0 -162000.0 -0.43 400160.0 -165000.0 -0.45 -0.6258 -0.9998 3068331 PK04_095104 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F05 compound treatment 402410.0 -294000.0 -0.78 547880.0 -16900.0 -0.05 -0.5872 -0.7477 3068563 PK04_095105 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F06 compound treatment 476650.0 -219000.0 -0.59 274830.0 -290000.0 -0.8 -0.9771 -0.9886 3186879 PK04_095106 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCCN6CCOCC6)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F07 compound treatment 287690.0 -408000.0 -1.09 262110.0 -303000.0 -0.83 -1.3587 -0.991 3187523 PK04_095107 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F08 compound treatment 343600.0 -352000.0 -0.94 784800.0 220000.0 0.6 -0.2384 -0.2132 3186563 PK04_095108 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F09 mock treatment 838880.0 143000.0 0.38 538890.0 -25900.0 -0.07 0.2197 0.5656 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F10 mock treatment 810010.0 114000.0 0.3 331140.0 -234000.0 -0.64 -0.2382 -0.3353 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F11 compound treatment 444490.0 -251000.0 -0.67 307560.0 -257000.0 -0.71 -0.9743 -0.9997 3187257 PK04_095109 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F12 compound treatment 292720.0 -403000.0 -1.08 303570.0 -261000.0 -0.72 -1.2687 -0.9805 3068241 PK04_095110 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F13 compound treatment 641660.0 -54300.0 -0.14 676680.0 112000.0 0.31 0.1147 0.3377 3068554 PK04_095111 COCCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F14 compound treatment 554880.0 -141000.0 -0.38 470810.0 -94000.0 -0.26 -0.4489 -0.983 3068362 PK04_095112 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)Sc4ccc(C)cc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F15 compound treatment 344400.0 -352000.0 -0.94 439480.0 -125000.0 -0.34 -0.9072 -0.9072 3186423 PK04_095113 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F16 compound treatment 758560.0 62600.0 0.17 393890.0 -171000.0 -0.47 -0.2135 -0.4286 3068012 PK04_095114 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F17 mock treatment 453820.0 -242000.0 -0.65 374110.0 -191000.0 -0.52 -0.8275 -0.9945 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F18 mock treatment 662760.0 -33200.0 -0.09 241600.0 -323000.0 -0.89 -0.6901 -0.7739 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F19 compound treatment 319560.0 -376000.0 -1.01 265400.0 -299000.0 -0.82 -1.2921 -0.995 3067568 PK04_095115 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F20 compound treatment 295880.0 -400000.0 -1.07 302450.0 -262000.0 -0.72 -1.2649 -0.9816 3068266 PK04_095116 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F21 compound treatment 304810.0 -391000.0 -1.04 292480.0 -272000.0 -0.75 -1.2674 -0.9865 3186419 PK04_095117 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F22 compound treatment 216120.0 -480000.0 -1.28 240960.0 -324000.0 -0.89 -1.5349 -0.984 3187524 PK04_095118 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F23 compound treatment 835410.0 139000.0 0.37 682050.0 117000.0 0.32 0.491 0.9973 3068017 PK04_095119 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)O)c4ccccc4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 F24 compound treatment 636670.0 -59300.0 -0.16 832770.0 268000.0 0.74 0.4083 0.5426 3186554 PK04_095120 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G01 compound treatment 455230.0 -241000.0 -0.64 436010.0 -129000.0 -0.35 -0.7046 -0.9603 3186418 PK04_095121 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G02 compound treatment 817440.0 122000.0 0.32 774270.0 209000.0 0.58 0.6361 0.9633 3067966 PK04_095122 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCN3CCOCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G03 mock treatment 630210.0 -65700.0 -0.18 534080.0 -30700.0 -0.08 -0.1838 -0.9436 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G04 mock treatment 920050.0 224000.0 0.6 471960.0 -92800.0 -0.25 0.243 0.3736 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G05 compound treatment 343550.0 -352000.0 -0.94 345890.0 -219000.0 -0.6 -1.0905 -0.9765 3068153 PK04_095123 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G06 compound treatment 548270.0 -148000.0 -0.39 550780.0 -14000.0 -0.04 -0.3061 -0.7725 3187356 PK04_095124 COCCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G07 compound treatment 601050.0 -94900.0 -0.25 665950.0 101000.0 0.28 0.0172 0.0456 3187173 PK04_095125 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G08 compound treatment 442560.0 -253000.0 -0.68 544910.0 -19900.0 -0.05 -0.5172 -0.7617 3068514 PK04_095126 CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G09 compound treatment 468860.0 -227000.0 -0.61 408570.0 -156000.0 -0.43 -0.7322 -0.9856 3187442 PK04_095127 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G10 compound treatment 643170.0 -52800.0 -0.14 785980.0 221000.0 0.61 0.3297 0.5289 3068420 PK04_095128 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G11 compound treatment 668000.0 -27900.0 -0.07 455400.0 -109000.0 -0.3 -0.2651 -0.8567 3187434 PK04_095129 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G12 compound treatment 192530.0 -503000.0 -1.34 260960.0 -304000.0 -0.83 -1.5406 -0.9736 3186416 PK04_095130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G13 compound treatment 332450.0 -363000.0 -0.97 206240.0 -359000.0 -0.98 -1.3826 -1.0 3068507 PK04_095131 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G14 compound treatment 684320.0 -11600.0 -0.03 277170.0 -288000.0 -0.79 -0.5803 -0.7343 3187162 PK04_095132 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G15 compound treatment 277440.0 -418000.0 -1.12 216760.0 -348000.0 -0.96 -1.4661 -0.997 3068602 PK04_095133 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G16 compound treatment 663130.0 -32800.0 -0.09 332680.0 -232000.0 -0.64 -0.5126 -0.7968 3187426 PK04_095134 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G17 compound treatment 217950.0 -478000.0 -1.28 283000.0 -282000.0 -0.77 -1.4498 -0.9712 3067567 PK04_095135 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G18 compound treatment 291770.0 -404000.0 -1.08 286820.0 -278000.0 -0.76 -1.303 -0.9856 3187525 PK04_095136 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G19 mock treatment 847840.0 152000.0 0.41 385440.0 -179000.0 -0.49 -0.0613 -0.0961 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G20 mock treatment 422850.0 -273000.0 -0.73 752710.0 188000.0 0.52 -0.151 -0.169 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G21 compound treatment 652900.0 -43000.0 -0.11 332810.0 -232000.0 -0.64 -0.5316 -0.8214 3187167 PK04_095137 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G22 compound treatment 763100.0 67200.0 0.18 326670.0 -238000.0 -0.65 -0.3354 -0.4948 3187174 PK04_095138 COc1ccccc1CN2[C@H]([C@H](C(=O)NC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G23 compound treatment 665450.0 -30500.0 -0.08 297340.0 -267000.0 -0.73 -0.5768 -0.7807 3068478 PK04_095139 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 G24 compound treatment 410600.0 -285000.0 -0.76 401360.0 -163000.0 -0.45 -0.8562 -0.9681 3068471 PK04_095140 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H01 compound treatment 513980.0 -182000.0 -0.49 769950.0 205000.0 0.56 0.0546 0.0734 3068149 PK04_095141 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H02 compound treatment 571060.0 -125000.0 -0.33 523360.0 -41400.0 -0.11 -0.3163 -0.8975 3068236 PK04_095142 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H03 mock treatment 880160.0 184000.0 0.49 346930.0 -218000.0 -0.6 -0.075 -0.0968 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H04 mock treatment 912370.0 216000.0 0.58 370880.0 -194000.0 -0.53 0.0323 0.0411 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H05 compound treatment 374140.0 -322000.0 -0.86 832030.0 267000.0 0.73 -0.089 -0.0788 3187083 PK04_095143 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H06 compound treatment 292380.0 -404000.0 -1.08 335170.0 -230000.0 -0.63 -1.208 -0.9674 3068265 PK04_095144 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H07 compound treatment 913720.0 218000.0 0.58 441330.0 -123000.0 -0.34 0.1716 0.2549 3068458 PK04_095145 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H08 compound treatment 609470.0 -86500.0 -0.23 467290.0 -97500.0 -0.27 -0.3526 -0.9973 3068401 PK04_095146 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H09 compound treatment 357160.0 -339000.0 -0.9 724340.0 160000.0 0.44 -0.3301 -0.3284 3187071 PK04_095147 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H10 compound treatment 379580.0 -316000.0 -0.84 453300.0 -112000.0 -0.31 -0.8139 -0.9057 3068139 PK04_095148 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H11 compound treatment 162310.0 -534000.0 -1.43 228480.0 -336000.0 -0.92 -1.6607 -0.9779 3187589 PK04_095149 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H12 compound treatment 387540.0 -308000.0 -0.82 369700.0 -195000.0 -0.54 -0.9612 -0.9783 3186627 PK04_095150 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H13 compound treatment 349050.0 -347000.0 -0.93 240410.0 -324000.0 -0.89 -1.2849 -0.9998 3187261 PK04_095151 CC(C)N1[C@H]([C@H](C(=O)NC2CC2)c3ccccc3C1=O)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H14 compound treatment 386150.0 -310000.0 -0.83 203270.0 -362000.0 -0.99 -1.2869 -0.9959 3186980 PK04_095152 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H15 compound treatment 522940.0 -173000.0 -0.46 292120.0 -273000.0 -0.75 -0.8561 -0.9731 3187166 PK04_095153 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H16 compound treatment 745780.0 49900.0 0.13 747650.0 183000.0 0.5 0.4491 0.8648 3186978 PK04_095154 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H17 compound treatment 493140.0 -203000.0 -0.54 455110.0 -110000.0 -0.3 -0.596 -0.9616 3187349 PK04_095155 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCCN(C)C)c3ccccc3C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H18 compound treatment 389180.0 -307000.0 -0.82 293640.0 -271000.0 -0.74 -1.1058 -0.9989 3068412 PK04_095156 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H19 mock treatment 320320.0 -376000.0 -1.0 698360.0 134000.0 0.37 -0.4501 -0.4214 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H20 mock treatment 277160.0 -419000.0 -1.12 465980.0 -98800.0 -0.27 -0.9828 -0.8539 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H21 compound treatment 830560.0 135000.0 0.36 371460.0 -193000.0 -0.53 -0.1211 -0.1888 3187512 PK04_095157 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H22 compound treatment 258630.0 -437000.0 -1.17 243940.0 -321000.0 -0.88 -1.4488 -0.9903 3186806 PK04_095158 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H23 compound treatment 366300.0 -330000.0 -0.88 421380.0 -143000.0 -0.39 -0.901 -0.9342 3068599 PK04_095159 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NC4CC4)c5ccccc5C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 H24 compound treatment 315040.0 -381000.0 -1.02 343130.0 -222000.0 -0.61 -1.1497 -0.9698 3187586 PK04_095160 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I01 compound treatment 472330.0 -224000.0 -0.6 688730.0 124000.0 0.34 -0.1817 -0.2644 3187165 PK04_095161 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I02 compound treatment 735420.0 39500.0 0.11 649170.0 84400.0 0.23 0.2384 0.9366 3068418 PK04_095162 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I03 compound treatment 646250.0 -49700.0 -0.13 534240.0 -30600.0 -0.08 -0.1532 -0.9756 3187178 PK04_095163 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I04 compound treatment 905440.0 210000.0 0.56 697700.0 133000.0 0.36 0.6537 0.9785 3068019 PK04_095164 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I05 mock treatment 766730.0 70800.0 0.19 746180.0 181000.0 0.5 0.4858 0.9121 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I06 mock treatment 454310.0 -242000.0 -0.65 526560.0 -38200.0 -0.1 -0.5306 -0.8115 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I07 compound treatment 550880.0 -145000.0 -0.39 375200.0 -190000.0 -0.52 -0.642 -0.9894 3068542 PK04_095165 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3Cc4ccccc4C3)C(=O)c5ccccc25)c6ccc(CO)cc6)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I08 compound treatment 778350.0 82400.0 0.22 822350.0 258000.0 0.71 0.6556 0.8853 3187345 PK04_095166 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I09 compound treatment 290090.0 -406000.0 -1.08 262760.0 -302000.0 -0.83 -1.3529 -0.9913 3067971 PK04_095167 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I10 compound treatment 504770.0 -191000.0 -0.51 446410.0 -118000.0 -0.33 -0.5909 -0.9762 3068641 PK04_095168 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I11 compound treatment 430510.0 -265000.0 -0.71 394400.0 -170000.0 -0.47 -0.8321 -0.9797 3187358 PK04_095169 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I12 compound treatment 704070.0 8140.0 0.02 542600.0 -22200.0 -0.06 -0.0277 -0.4285 3068653 PK04_095170 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I13 compound treatment 453160.0 -243000.0 -0.65 664530.0 99700.0 0.27 -0.2649 -0.3764 3067962 PK04_095171 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I14 compound treatment 481280.0 -215000.0 -0.57 292280.0 -273000.0 -0.75 -0.9345 -0.9914 3068606 PK04_095172 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I15 compound treatment 424560.0 -271000.0 -0.72 466560.0 -98200.0 -0.27 -0.7033 -0.9093 3068476 PK04_095173 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I16 compound treatment 239280.0 -457000.0 -1.22 282520.0 -282000.0 -0.77 -1.4105 -0.976 3186417 PK04_095174 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I17 compound treatment 602450.0 -93500.0 -0.25 752590.0 188000.0 0.52 0.188 0.3282 3187268 PK04_095175 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I18 compound treatment 677920.0 -18000.0 -0.05 377560.0 -187000.0 -0.51 -0.3975 -0.7699 3187264 PK04_095176 CC(C)N1[C@H]([C@H](C(=O)NCC(F)(F)F)c2ccccc2C1=O)c3ccc(CO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I19 compound treatment 311400.0 -385000.0 -1.03 450890.0 -114000.0 -0.31 -0.9474 -0.8824 3186499 PK04_095177 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I20 compound treatment 433600.0 -262000.0 -0.7 408810.0 -156000.0 -0.43 -0.7983 -0.9721 3068422 PK04_095178 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I21 mock treatment 690650.0 -5280.0 -0.01 293970.0 -271000.0 -0.74 -0.5357 -0.7204 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I22 mock treatment 728920.0 33000.0 0.09 264260.0 -301000.0 -0.83 -0.5211 -0.628 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I23 compound treatment 587070.0 -109000.0 -0.29 271920.0 -293000.0 -0.8 -0.7742 -0.9054 3068550 PK04_095179 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(C)C)C(=O)c3ccccc23)c4ccc(CO)cc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 I24 compound treatment 240250.0 -456000.0 -1.22 259330.0 -305000.0 -0.84 -1.4537 -0.9835 3187258 PK04_095180 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4Cc5ccccc5C4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J01 compound treatment 508910.0 -187000.0 -0.5 455520.0 -109000.0 -0.3 -0.5654 -0.9703 3187273 PK04_095181 CC(C)CNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J02 compound treatment 890350.0 194000.0 0.52 856960.0 292000.0 0.8 0.9344 0.9779 3186630 PK04_095182 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J03 compound treatment 874850.0 179000.0 0.48 805720.0 241000.0 0.66 0.8056 0.9873 3187353 PK04_095183 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(=O)c3ccccc32)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J04 compound treatment 479640.0 -216000.0 -0.58 477860.0 -86900.0 -0.24 -0.5773 -0.9235 3187588 PK04_095184 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)O)c3ccccc3C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J05 mock treatment 418140.0 -278000.0 -0.74 462090.0 -103000.0 -0.28 -0.7241 -0.9122 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J06 mock treatment 586590.0 -109000.0 -0.29 728160.0 163000.0 0.45 0.1106 0.2067 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J07 compound treatment 425690.0 -270000.0 -0.72 374510.0 -190000.0 -0.52 -0.8798 -0.9874 3186420 PK04_095185 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J08 compound treatment 222800.0 -473000.0 -1.26 298000.0 -267000.0 -0.73 -1.4115 -0.9664 3186722 PK04_095186 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J09 compound treatment 379270.0 -317000.0 -0.85 336120.0 -229000.0 -0.63 -1.042 -0.9892 3186426 PK04_095187 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J10 compound treatment 730920.0 35000.0 0.09 549680.0 -15100.0 -0.04 0.0367 0.3591 3186639 PK04_095188 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J11 compound treatment 377120.0 -319000.0 -0.85 471200.0 -93600.0 -0.26 -0.7838 -0.8812 3187270 PK04_095189 CC(C)NC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J12 compound treatment 488840.0 -207000.0 -0.55 749220.0 184000.0 0.51 -0.0331 -0.0442 3067980 PK04_095190 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J13 compound treatment 552830.0 -143000.0 -0.38 353930.0 -211000.0 -0.58 -0.6796 -0.9797 3186421 PK04_095191 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J14 compound treatment 235360.0 -461000.0 -1.23 519430.0 -45400.0 -0.12 -0.958 -0.7748 3068150 PK04_095192 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J15 compound treatment 367010.0 -329000.0 -0.88 800960.0 236000.0 0.65 -0.1628 -0.1491 3068598 PK04_095193 CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J16 compound treatment 258190.0 -438000.0 -1.17 259050.0 -306000.0 -0.84 -1.4203 -0.9868 3068324 PK04_095194 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J17 compound treatment 167710.0 -528000.0 -1.41 187360.0 -377000.0 -1.04 -1.7304 -0.9885 3067973 PK04_095195 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J18 compound treatment 634090.0 -61800.0 -0.17 537930.0 -26900.0 -0.07 -0.169 -0.934 3068414 PK04_095196 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J19 compound treatment 536380.0 -160000.0 -0.43 461240.0 -104000.0 -0.28 -0.5024 -0.9807 3187085 PK04_095197 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J20 compound treatment 338320.0 -358000.0 -0.96 377390.0 -187000.0 -0.51 -1.0392 -0.9579 3186884 PK04_095198 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J21 mock treatment 772850.0 76900.0 0.21 314670.0 -250000.0 -0.69 -0.3403 -0.4748 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J22 mock treatment 581720.0 -114000.0 -0.31 450880.0 -114000.0 -0.31 -0.4369 -0.9999 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J23 compound treatment 554280.0 -142000.0 -0.38 336920.0 -228000.0 -0.63 -0.7099 -0.971 3187082 PK04_095199 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 J24 compound treatment 268210.0 -428000.0 -1.14 542430.0 -22400.0 -0.06 -0.8513 -0.7441 3068227 PK04_095200 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K01 compound treatment 504360.0 -192000.0 -0.51 565440.0 635.0 0.0 -0.3606 -0.7047 3187514 PK04_095201 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K02 compound treatment 820060.0 124000.0 0.33 888900.0 324000.0 0.89 0.8636 0.9095 3187168 PK04_095202 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccc(OC(F)(F)F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K03 compound treatment 441280.0 -255000.0 -0.68 794580.0 230000.0 0.63 -0.0349 -0.0376 3068143 PK04_095203 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC5CC5)c6ccccc6C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K04 compound treatment 705820.0 9890.0 0.03 390560.0 -174000.0 -0.48 -0.3196 -0.667 3187275 PK04_095204 CN(C)CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K05 compound treatment 537840.0 -158000.0 -0.42 386280.0 -179000.0 -0.49 -0.6452 -0.9972 3187271 PK04_095205 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K06 compound treatment 446780.0 -249000.0 -0.67 376840.0 -188000.0 -0.52 -0.8355 -0.9921 3186561 PK04_095206 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K07 mock treatment 519320.0 -177000.0 -0.47 823230.0 258000.0 0.71 0.1681 0.1973 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K08 mock treatment 506810.0 -189000.0 -0.51 590040.0 25200.0 0.07 -0.3082 -0.6045 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K09 compound treatment 513230.0 -183000.0 -0.49 614240.0 49400.0 0.14 -0.2491 -0.4918 3068519 PK04_095207 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K10 compound treatment 738830.0 42900.0 0.11 508010.0 -56800.0 -0.16 -0.0292 -0.1511 3068466 PK04_095208 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K11 compound treatment 545640.0 -150000.0 -0.4 604350.0 39500.0 0.11 -0.2071 -0.498 3068556 PK04_095209 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K12 compound treatment 278850.0 -417000.0 -1.11 314930.0 -250000.0 -0.69 -1.2728 -0.9729 3067978 PK04_095210 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K13 compound treatment 826320.0 130000.0 0.35 658830.0 94000.0 0.26 0.4288 0.9891 3068499 PK04_095211 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K14 compound treatment 392860.0 -303000.0 -0.81 676000.0 111000.0 0.31 -0.3565 -0.4121 3068588 PK04_095212 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K15 mock treatment 834900.0 139000.0 0.37 664210.0 99400.0 0.27 0.4554 0.9886 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K16 mock treatment 965850.0 270000.0 0.72 614600.0 49800.0 0.14 0.6065 0.8265 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K17 compound treatment 289160.0 -407000.0 -1.09 327370.0 -237000.0 -0.65 -1.2292 -0.9701 3068009 PK04_095213 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K18 compound treatment 15690.0 -680000.0 -1.82 18080.0 -547000.0 -1.5 -2.3461 -0.9955 3186498 PK04_095214 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCCN(C)C)c5ccccc5C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K19 compound treatment 537490.0 -158000.0 -0.42 824910.0 260000.0 0.71 0.2057 0.2478 3068472 PK04_095215 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K20 compound treatment 398450.0 -297000.0 -0.79 237120.0 -328000.0 -0.9 -1.198 -0.9981 3187259 PK04_095216 COCCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K21 compound treatment 860290.0 164000.0 0.44 392390.0 -172000.0 -0.47 -0.0243 -0.0376 3187078 PK04_095217 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K22 compound treatment 563640.0 -132000.0 -0.35 654980.0 90200.0 0.25 -0.0748 -0.1734 3068508 PK04_095218 COc1ccccc1CN2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K23 mock treatment 460100.0 -236000.0 -0.63 288160.0 -277000.0 -0.76 -0.9825 -0.9957 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 K24 mock treatment 866690.0 171000.0 0.46 899690.0 335000.0 0.92 0.9726 0.9477 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L01 compound treatment 784030.0 88100.0 0.24 513760.0 -51000.0 -0.14 0.0673 0.2457 3187175 PK04_095219 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCCN(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L02 compound treatment 295520.0 -400000.0 -1.07 290590.0 -274000.0 -0.75 -1.2886 -0.9852 3186714 PK04_095220 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L03 compound treatment 361010.0 -335000.0 -0.89 524590.0 -40200.0 -0.11 -0.7106 -0.7884 3067967 PK04_095221 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCc3ccccc3)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L04 compound treatment 399370.0 -297000.0 -0.79 789700.0 225000.0 0.62 -0.1235 -0.123 3186429 PK04_095222 CC(C)CN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L05 compound treatment 828000.0 132000.0 0.35 504820.0 -60000.0 -0.16 0.133 0.3416 3068540 PK04_095223 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L06 compound treatment 853600.0 158000.0 0.42 450330.0 -114000.0 -0.31 0.0756 0.1438 3186551 PK04_095224 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L07 mock treatment 826490.0 131000.0 0.35 627040.0 62200.0 0.17 0.3674 0.9461 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L08 mock treatment 845760.0 150000.0 0.4 594750.0 29900.0 0.08 0.3411 0.8349 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L09 compound treatment 461240.0 -235000.0 -0.63 477990.0 -86800.0 -0.24 -0.6118 -0.9122 3187518 PK04_095225 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L10 compound treatment 700110.0 4180.0 0.01 875840.0 311000.0 0.85 0.6117 0.7163 3068144 PK04_095226 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCc5ccccc5)c6ccccc6C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L11 compound treatment 673030.0 -22900.0 -0.06 650440.0 85600.0 0.24 0.123 0.5063 3187076 PK04_095227 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L12 compound treatment 286620.0 -409000.0 -1.09 320270.0 -245000.0 -0.67 -1.2478 -0.9726 3068313 PK04_095228 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L13 compound treatment 675790.0 -20100.0 -0.05 735530.0 171000.0 0.47 0.2934 0.6219 3187347 PK04_095229 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(C)C)C(=O)c3ccccc32)c4ccc(CO)cc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L14 compound treatment 739800.0 43900.0 0.12 719870.0 155000.0 0.43 0.3839 0.8694 3068194 PK04_095230 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(C)C)C4=O)c6ccccc6C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L15 mock treatment 839790.0 144000.0 0.38 487750.0 -77100.0 -0.21 0.1221 0.2784 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L16 mock treatment 844320.0 148000.0 0.4 620430.0 55600.0 0.15 0.3882 0.9141 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L17 compound treatment 628270.0 -67700.0 -0.18 452320.0 -112000.0 -0.31 -0.3462 -0.9674 3068510 PK04_095231 COc1ccccc1CN2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L18 compound treatment 302400.0 -394000.0 -1.05 281640.0 -283000.0 -0.78 -1.293 -0.989 3068263 PK04_095232 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3I)Sc4ccc(C)cc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L19 compound treatment 672700.0 -23200.0 -0.06 592480.0 27700.0 0.08 0.0099 0.1004 3067958 PK04_095233 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L20 compound treatment 680800.0 -15100.0 -0.04 245530.0 -319000.0 -0.88 -0.6484 -0.7389 3068403 PK04_095234 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L21 compound treatment 773620.0 77700.0 0.21 734270.0 169000.0 0.47 0.4757 0.9338 3187163 PK04_095235 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L22 compound treatment 538110.0 -158000.0 -0.42 519940.0 -44900.0 -0.12 -0.3852 -0.8771 3186433 PK04_095236 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c5ccc(cc5)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L23 mock treatment 868280.0 172000.0 0.46 534240.0 -30600.0 -0.08 0.2662 0.5688 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 L24 mock treatment 863360.0 167000.0 0.45 492640.0 -72200.0 -0.2 0.1761 0.3601 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M01 compound treatment 779070.0 83100.0 0.22 811130.0 246000.0 0.68 0.6352 0.8924 3187444 PK04_095237 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M02 compound treatment 603560.0 -92400.0 -0.25 780080.0 215000.0 0.59 0.2435 0.3801 3068593 PK04_095238 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NC3CC3)c4ccccc4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M03 compound treatment 309920.0 -386000.0 -1.03 325600.0 -239000.0 -0.66 -1.1934 -0.9763 3187441 PK04_095239 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M04 compound treatment 825850.0 130000.0 0.35 480410.0 -84400.0 -0.23 0.0815 0.1954 3068649 PK04_095240 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M05 compound treatment 283220.0 -413000.0 -1.1 394050.0 -171000.0 -0.47 -1.111 -0.9274 3068152 PK04_095241 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M06 compound treatment 765120.0 69200.0 0.18 636000.0 71200.0 0.2 0.2689 0.9996 3068655 PK04_095242 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M07 compound treatment 796000.0 100000.0 0.27 611970.0 47200.0 0.13 0.2806 0.9447 3068005 PK04_095243 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M08 compound treatment 759800.0 63900.0 0.17 525770.0 -39000.0 -0.11 0.0448 0.2226 3187084 PK04_095244 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M09 mock treatment 692820.0 -3110.0 -0.01 807330.0 243000.0 0.67 0.4649 0.6982 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M10 mock treatment 747300.0 51400.0 0.14 812800.0 248000.0 0.68 0.5785 0.8329 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M11 compound treatment 561680.0 -134000.0 -0.36 537570.0 -27200.0 -0.07 -0.3064 -0.8366 3186422 PK04_095245 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M12 compound treatment 127260.0 -569000.0 -1.52 178900.0 -386000.0 -1.06 -1.8232 -0.9845 3068142 PK04_095246 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M13 mock treatment 814930.0 119000.0 0.32 770080.0 205000.0 0.56 0.6233 0.9633 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M14 mock treatment 617300.0 -78600.0 -0.21 774570.0 210000.0 0.58 0.2587 0.422 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M15 compound treatment 698310.0 2380.0 0.01 739040.0 174000.0 0.48 0.3427 0.7164 3068557 PK04_095247 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M16 compound treatment 752830.0 56900.0 0.15 458460.0 -106000.0 -0.29 -0.099 -0.3007 3187170 PK04_095248 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M17 compound treatment 818880.0 123000.0 0.33 830820.0 266000.0 0.73 0.7486 0.9349 3187431 PK04_095249 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M18 compound treatment 726300.0 30400.0 0.08 600380.0 35600.0 0.1 0.1264 0.9957 3187074 PK04_095250 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M19 compound treatment 609330.0 -86600.0 -0.23 586120.0 21300.0 0.06 -0.1222 -0.5121 3068552 PK04_095251 CC(C)NC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M20 compound treatment 633140.0 -62800.0 -0.17 304550.0 -260000.0 -0.71 -0.6238 -0.85 3068014 PK04_095252 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)O)c5ccccc5C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M21 compound treatment 351090.0 -345000.0 -0.92 601060.0 36300.0 0.1 -0.5809 -0.627 3187086 PK04_095253 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M22 compound treatment 764320.0 68400.0 0.18 781120.0 216000.0 0.59 0.5491 0.8837 3187428 PK04_095254 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M23 compound treatment 718300.0 22400.0 0.06 500540.0 -64300.0 -0.18 -0.0825 -0.4429 3187081 PK04_095255 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 M24 compound treatment 717710.0 21800.0 0.06 556700.0 -8110.0 -0.02 0.0254 0.4078 3068003 PK04_095256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N01 compound treatment 706480.0 10600.0 0.03 710110.0 145000.0 0.4 0.302 0.7552 3187360 PK04_095257 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N02 compound treatment 861630.0 166000.0 0.44 822090.0 257000.0 0.71 0.8124 0.9746 3068231 PK04_095258 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N03 compound treatment 818720.0 123000.0 0.33 659170.0 94400.0 0.26 0.4151 0.9932 3068544 PK04_095259 CC(C)NC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N04 compound treatment 484170.0 -212000.0 -0.57 461670.0 -103000.0 -0.28 -0.6002 -0.9488 3187527 PK04_095260 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N05 compound treatment 793340.0 97400.0 0.26 552970.0 -11800.0 -0.03 0.161 0.614 3187260 PK04_095261 CCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N06 compound treatment 256920.0 -439000.0 -1.17 251530.0 -313000.0 -0.86 -1.4373 -0.9884 3186724 PK04_095262 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N07 compound treatment 813700.0 118000.0 0.31 698010.0 133000.0 0.37 0.481 0.9972 3068501 PK04_095263 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N08 compound treatment 599790.0 -96100.0 -0.26 609440.0 44600.0 0.12 -0.0949 -0.3336 3186871 PK04_095264 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N09 mock treatment 792360.0 96400.0 0.26 801840.0 237000.0 0.65 0.6423 0.9177 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N10 mock treatment 822500.0 127000.0 0.34 759910.0 195000.0 0.54 0.6178 0.9754 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N11 compound treatment 762250.0 66300.0 0.18 746170.0 181000.0 0.5 0.4773 0.9032 3187070 PK04_095265 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N12 compound treatment 286490.0 -409000.0 -1.09 308040.0 -257000.0 -0.7 -1.2718 -0.9774 3186804 PK04_095266 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N13 mock treatment 774880.0 79000.0 0.21 817600.0 253000.0 0.69 0.6399 0.8821 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N14 mock treatment 855520.0 160000.0 0.43 748980.0 184000.0 0.51 0.659 0.9964 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N15 compound treatment 223110.0 -473000.0 -1.26 324250.0 -241000.0 -0.66 -1.36 -0.9543 3186424 PK04_095267 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N16 compound treatment 656260.0 -39700.0 -0.11 574770.0 9960.0 0.03 -0.0556 -0.5079 3068226 PK04_095268 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N17 compound treatment 747520.0 51600.0 0.14 371300.0 -194000.0 -0.53 -0.2782 -0.5069 3068455 PK04_095269 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N18 compound treatment 372530.0 -323000.0 -0.86 632550.0 67700.0 0.19 -0.4793 -0.5424 3068137 PK04_095270 CN(C)CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N19 compound treatment 807320.0 111000.0 0.3 852360.0 288000.0 0.79 0.7686 0.911 3068647 PK04_095271 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N20 compound treatment 222760.0 -473000.0 -1.26 416480.0 -148000.0 -0.41 -1.1816 -0.8899 3186492 PK04_095272 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N21 compound treatment 524340.0 -172000.0 -0.46 690920.0 126000.0 0.35 -0.0792 -0.138 3067959 PK04_095273 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N22 compound treatment 501130.0 -195000.0 -0.52 485880.0 -78900.0 -0.22 -0.5211 -0.9246 3187526 PK04_095274 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)O)c3ccc(cc3)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N23 compound treatment 497400.0 -199000.0 -0.53 469830.0 -95000.0 -0.26 -0.5593 -0.9466 3068468 PK04_095275 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 N24 compound treatment 604120.0 -91800.0 -0.25 385380.0 -179000.0 -0.49 -0.5217 -0.9481 3068222 PK04_095276 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O01 compound treatment 502840.0 -193000.0 -0.52 418360.0 -146000.0 -0.4 -0.649 -0.9924 3068590 PK04_095277 CC(C)NC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O02 compound treatment 346440.0 -349000.0 -0.93 262030.0 -303000.0 -0.83 -1.2479 -0.9983 3067977 PK04_095278 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O03 compound treatment 427200.0 -269000.0 -0.72 603810.0 39000.0 0.11 -0.4318 -0.595 3068512 PK04_095279 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O04 compound treatment 733610.0 37700.0 0.1 501210.0 -63600.0 -0.17 -0.0523 -0.2595 3068637 PK04_095280 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O05 compound treatment 753300.0 57400.0 0.15 716010.0 151000.0 0.42 0.4019 0.9082 3068459 PK04_095281 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(cc(c4)C(F)(F)F)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O06 compound treatment 751680.0 55800.0 0.15 516270.0 -48500.0 -0.13 0.0111 0.0554 3187520 PK04_095282 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O07 compound treatment 662780.0 -33200.0 -0.09 624020.0 59200.0 0.16 0.0523 0.2828 3186989 PK04_095283 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O08 compound treatment 764610.0 68700.0 0.18 604390.0 39600.0 0.11 0.2066 0.9688 3187364 PK04_095284 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O09 compound treatment 594720.0 -101000.0 -0.27 643160.0 78400.0 0.22 -0.039 -0.113 3068604 PK04_095285 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O10 compound treatment 513920.0 -182000.0 -0.49 699570.0 135000.0 0.37 -0.0821 -0.1344 3187362 PK04_095286 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O11 mock treatment 742500.0 46600.0 0.12 659850.0 95000.0 0.26 0.2725 0.9426 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O12 mock treatment 836350.0 140000.0 0.38 728050.0 163000.0 0.45 0.5821 0.9961 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O13 compound treatment 738770.0 42800.0 0.11 781510.0 217000.0 0.59 0.5016 0.8279 3068644 PK04_095287 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O14 compound treatment 695160.0 -770.0 0.0 477450.0 -87400.0 -0.24 -0.171 -0.7131 3068464 PK04_095288 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O15 compound treatment 277600.0 -418000.0 -1.12 250400.0 -314000.0 -0.86 -1.4004 -0.9919 3187516 PK04_095289 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O16 compound treatment 795250.0 99300.0 0.27 615900.0 51100.0 0.14 0.2868 0.9556 3187164 PK04_095290 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O17 compound treatment 618020.0 -77900.0 -0.21 593890.0 29100.0 0.08 -0.0907 -0.4069 3187177 PK04_095291 CC(C)CNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O18 compound treatment 445610.0 -250000.0 -0.67 601440.0 36600.0 0.1 -0.4017 -0.5941 3068546 PK04_095292 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O19 compound treatment 553240.0 -143000.0 -0.38 432650.0 -132000.0 -0.36 -0.526 -0.9997 3187256 PK04_095293 CC(C)CNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O20 compound treatment 514240.0 -182000.0 -0.49 506480.0 -58300.0 -0.16 -0.4564 -0.8931 3187088 PK04_095294 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O21 compound treatment 306740.0 -389000.0 -1.04 569280.0 4470.0 0.01 -0.7264 -0.6987 3186494 PK04_095295 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(C)C)c5ccccc5C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O22 compound treatment 681610.0 -14300.0 -0.04 259760.0 -305000.0 -0.84 -0.6192 -0.7386 3187161 PK04_095296 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O23 compound treatment 528700.0 -167000.0 -0.45 331790.0 -233000.0 -0.64 -0.7682 -0.9846 3187267 PK04_095297 CC(C)CNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 O24 compound treatment 513540.0 -182000.0 -0.49 689280.0 124000.0 0.34 -0.1028 -0.1728 3068502 PK04_095298 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P01 compound treatment 382990.0 -313000.0 -0.84 405400.0 -159000.0 -0.44 -0.9005 -0.9544 3068591 PK04_095299 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2CC4(CC5CC6CC(C5)C4)C6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P02 compound treatment 512830.0 -183000.0 -0.49 477120.0 -87700.0 -0.24 -0.516 -0.9467 3187521 PK04_095300 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P03 compound treatment 465090.0 -231000.0 -0.62 313410.0 -251000.0 -0.69 -0.924 -0.9984 3186990 PK04_095301 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P04 compound treatment 430310.0 -266000.0 -0.71 489710.0 -75100.0 -0.21 -0.6475 -0.8763 3186985 PK04_095302 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P05 compound treatment 295270.0 -401000.0 -1.07 479870.0 -84900.0 -0.23 -0.9216 -0.8414 3067579 PK04_095303 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P06 compound treatment 447940.0 -248000.0 -0.66 432960.0 -132000.0 -0.36 -0.7243 -0.9596 3186975 PK04_095304 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P07 compound treatment 542760.0 -153000.0 -0.41 520320.0 -44500.0 -0.12 -0.3756 -0.8798 3068548 PK04_095305 CC(C)CNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P08 compound treatment 414960.0 -281000.0 -0.75 387200.0 -178000.0 -0.49 -0.8754 -0.9782 3067563 PK04_095306 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CCN5CCOCC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P09 compound treatment 359800.0 -336000.0 -0.9 386370.0 -178000.0 -0.49 -0.9812 -0.9594 3067961 PK04_095307 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P10 compound treatment 338760.0 -357000.0 -0.95 382560.0 -182000.0 -0.5 -1.0284 -0.9546 3068015 PK04_095308 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P11 mock treatment 505220.0 -191000.0 -0.51 293310.0 -271000.0 -0.75 -0.8872 -0.9828 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P12 mock treatment 297600.0 -398000.0 -1.06 445920.0 -119000.0 -0.33 -0.9831 -0.8834 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P13 compound treatment 275970.0 -420000.0 -1.12 377200.0 -188000.0 -0.52 -1.1574 -0.9377 3187510 PK04_095309 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P14 compound treatment 274720.0 -421000.0 -1.13 257950.0 -307000.0 -0.84 -1.3912 -0.9898 3186495 PK04_095310 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCN5CCOCC5)c6ccccc6C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P15 compound treatment 420010.0 -276000.0 -0.74 434490.0 -130000.0 -0.36 -0.7741 -0.9449 3187437 PK04_095311 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P16 compound treatment 303590.0 -392000.0 -1.05 405210.0 -160000.0 -0.44 -1.0508 -0.9251 3186625 PK04_095312 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C(C)C)C4=O)c6ccccc6C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P17 compound treatment 324040.0 -372000.0 -0.99 290240.0 -275000.0 -0.75 -1.2354 -0.9907 3068541 PK04_095313 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P18 compound treatment 238560.0 -457000.0 -1.22 255390.0 -309000.0 -0.85 -1.4645 -0.9842 3186878 PK04_095314 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NC6CC6)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P19 compound treatment 161440.0 -534000.0 -1.43 190400.0 -374000.0 -1.03 -1.7363 -0.987 3187513 PK04_095315 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P20 compound treatment 129470.0 -566000.0 -1.51 195270.0 -370000.0 -1.01 -1.7872 -0.9811 3068271 PK04_095316 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCc6ccccc6)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P21 compound treatment 151330.0 -545000.0 -1.45 197180.0 -368000.0 -1.01 -1.7422 -0.9841 3068008 PK04_095317 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P22 compound treatment 136750.0 -559000.0 -1.49 146350.0 -418000.0 -1.15 -1.8685 -0.9916 3068262 PK04_095318 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P23 compound treatment 497790.0 -198000.0 -0.53 303230.0 -262000.0 -0.72 -0.882 -0.9887 3068469 PK04_095319 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2095 P24 compound treatment 206500.0 -489000.0 -1.31 189720.0 -375000.0 -1.03 -1.6525 -0.993 3186794 PK04_095320 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A01 compound treatment 749730.0 106000.0 0.28 545920.0 -45300.0 -0.12 0.1114 0.3616 3186490 PK04_096001 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A02 compound treatment 628050.0 -16100.0 -0.04 782760.0 192000.0 0.53 0.3414 0.647 3186641 PK04_096002 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A03 compound treatment 310780.0 -333000.0 -0.89 291840.0 -299000.0 -0.82 -1.2109 -0.9992 3068261 PK04_096003 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A04 compound treatment 231310.0 -413000.0 -1.1 410310.0 -181000.0 -0.5 -1.131 -0.9351 3186971 PK04_096004 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A05 compound treatment 399040.0 -245000.0 -0.65 803450.0 212000.0 0.58 -0.051 -0.0582 3186883 PK04_096005 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A06 compound treatment 274760.0 -369000.0 -0.99 267050.0 -324000.0 -0.89 -1.327 -0.9987 3068309 PK04_096006 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A07 compound treatment 251550.0 -393000.0 -1.05 254660.0 -337000.0 -0.92 -1.3949 -0.998 3186716 PK04_096007 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A08 compound treatment 330400.0 -314000.0 -0.84 662350.0 71100.0 0.2 -0.4545 -0.5282 3068367 PK04_096008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)Sc6ccc(C)cc6)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A09 compound treatment 727610.0 83400.0 0.22 753090.0 162000.0 0.44 0.4718 0.949 3068224 PK04_096009 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A10 compound treatment 815300.0 171000.0 0.46 394940.0 -196000.0 -0.54 -0.0579 -0.0819 3186633 PK04_096010 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5C(F)(F)F)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A11 compound treatment 765120.0 121000.0 0.32 650730.0 59500.0 0.16 0.3439 0.9501 3186986 PK04_096011 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A12 compound treatment 538040.0 -106000.0 -0.28 526560.0 -64700.0 -0.18 -0.326 -0.9746 3186640 PK04_096012 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A13 mock treatment 811450.0 167000.0 0.45 378080.0 -213000.0 -0.59 -0.0979 -0.1329 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A14 mock treatment 896330.0 252000.0 0.67 391630.0 -200000.0 -0.55 0.0888 0.1022 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A15 compound treatment 766080.0 122000.0 0.33 366100.0 -225000.0 -0.62 -0.2068 -0.296 3186881 PK04_096013 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A16 compound treatment 301760.0 -342000.0 -0.91 291430.0 -300000.0 -0.82 -1.2287 -0.9986 3186790 PK04_096014 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A17 compound treatment 396720.0 -247000.0 -0.66 778300.0 187000.0 0.51 -0.1042 -0.1245 3186485 PK04_096015 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A18 compound treatment 262790.0 -381000.0 -1.02 246420.0 -345000.0 -0.95 -1.3897 -0.9993 3186802 PK04_096016 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A19 compound treatment 392350.0 -252000.0 -0.67 731640.0 140000.0 0.39 -0.203 -0.2619 3068405 PK04_096017 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A20 compound treatment 252360.0 -392000.0 -1.05 525380.0 -65800.0 -0.18 -0.8678 -0.8171 3068141 PK04_096018 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A21 compound treatment 389090.0 -255000.0 -0.68 780110.0 189000.0 0.52 -0.1151 -0.1344 3186624 PK04_096019 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5OC)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A22 compound treatment 672860.0 28700.0 0.08 767050.0 176000.0 0.48 0.3955 0.8092 3068200 PK04_096020 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCCN(C)C)C4=O)c6ccccc6C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A23 compound treatment 656040.0 11900.0 0.03 666850.0 75600.0 0.21 0.1692 0.8057 3068358 PK04_096021 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 A24 compound treatment 611360.0 -32800.0 -0.09 525020.0 -66200.0 -0.18 -0.1905 -0.9441 3068371 PK04_096022 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B01 compound treatment 774750.0 131000.0 0.35 603390.0 12200.0 0.03 0.2702 0.7713 3187511 PK04_096023 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCC(F)(F)F)c3ccc(cc3)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B02 compound treatment 761710.0 118000.0 0.31 711300.0 120000.0 0.33 0.4551 0.9997 3187030 PK04_096024 OCCCc1cc[n+](Cc2cccc(OC(F)(F)F)c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B03 compound treatment 355560.0 -289000.0 -0.77 411760.0 -179000.0 -0.49 -0.8935 -0.9766 3187169 PK04_096025 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B04 compound treatment 786910.0 143000.0 0.38 735960.0 145000.0 0.4 0.5506 0.9998 3068853 PK04_096026 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B05 compound treatment 761170.0 117000.0 0.31 610900.0 19700.0 0.05 0.2592 0.8172 3068457 PK04_096027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B06 compound treatment 940890.0 297000.0 0.79 786210.0 195000.0 0.54 0.9389 0.9818 3068854 PK04_096028 C[n+]1ccc2ccc(O)cc2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B07 compound treatment 634720.0 -9460.0 -0.03 652800.0 61600.0 0.17 0.1017 0.5948 3187352 PK04_096029 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCCN4CCOCC4)c5ccccc5C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B08 compound treatment 750010.0 106000.0 0.28 559070.0 -32200.0 -0.09 0.1375 0.4642 3187112 PK04_096030 COc1cc2CC[N+](=Cc2cc1O)Cc3cc4OCOc4cc3Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B09 compound treatment 561720.0 -82500.0 -0.22 426050.0 -165000.0 -0.45 -0.4764 -0.945 3068505 PK04_096031 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B10 compound treatment 887950.0 244000.0 0.65 792550.0 201000.0 0.55 0.8512 0.9967 3068855 PK04_096032 C[n+]1ccc(CCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B11 compound treatment 709850.0 65700.0 0.18 700020.0 109000.0 0.3 0.3352 0.9678 3068374 PK04_096033 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B12 compound treatment 329130.0 -315000.0 -0.84 304010.0 -287000.0 -0.79 -1.1526 -0.9995 3187113 PK04_096034 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C=C)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B13 mock treatment 767200.0 123000.0 0.33 807940.0 217000.0 0.59 0.6531 0.9608 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B14 mock treatment 459770.0 -184000.0 -0.49 383490.0 -208000.0 -0.57 -0.7516 -0.9973 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B15 compound treatment 660900.0 16700.0 0.04 709010.0 118000.0 0.32 0.2602 0.7972 3187255 PK04_096035 COCCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B16 compound treatment 502530.0 -142000.0 -0.38 359220.0 -232000.0 -0.64 -0.7179 -0.9691 3068856 PK04_096036 Oc1ccc2cc[n+](Cc3sc4ccccc4c3Cl)cc2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B17 compound treatment 318500.0 -326000.0 -0.87 433350.0 -158000.0 -0.43 -0.9216 -0.9482 3068608 PK04_096037 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B18 compound treatment 295710.0 -348000.0 -0.93 217530.0 -374000.0 -1.03 -1.3836 -0.9988 3187114 PK04_096038 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C5CC5)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B19 compound treatment 867040.0 223000.0 0.6 673220.0 82000.0 0.23 0.5801 0.9115 3187171 PK04_096039 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B20 compound treatment 442610.0 -202000.0 -0.54 371910.0 -219000.0 -0.6 -0.8064 -0.9984 3068857 PK04_096040 OCCCc1cc[n+](Cc2ccc(o2)[N+](=O)[O-])cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B21 compound treatment 938080.0 294000.0 0.79 809040.0 218000.0 0.6 0.9779 0.991 3068424 PK04_096041 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B22 compound treatment 719960.0 75800.0 0.2 749570.0 158000.0 0.43 0.4505 0.9395 3187115 PK04_096042 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B23 compound treatment 622400.0 -21800.0 -0.06 824110.0 233000.0 0.64 0.411 0.6401 3187072 PK04_096043 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 B24 compound treatment 701640.0 57500.0 0.15 476330.0 -115000.0 -0.32 -0.1145 -0.3265 3187116 PK04_096044 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C01 compound treatment 748210.0 104000.0 0.28 709320.0 118000.0 0.32 0.4257 0.997 3068218 PK04_096045 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C02 compound treatment 545920.0 -98300.0 -0.26 302310.0 -289000.0 -0.79 -0.7464 -0.8934 3186566 PK04_096046 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C03 compound treatment 608800.0 -35400.0 -0.09 617620.0 26400.0 0.07 -0.0156 -0.1308 3186549 PK04_096047 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C04 compound treatment 255550.0 -389000.0 -1.04 231230.0 -360000.0 -0.99 -1.4328 -0.9997 3186726 PK04_096048 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C05 compound treatment 240830.0 -403000.0 -1.08 216640.0 -375000.0 -1.03 -1.489 -0.9997 3186792 PK04_096049 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C06 compound treatment 697200.0 53000.0 0.14 729870.0 139000.0 0.38 0.3693 0.9093 3186987 PK04_096050 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C07 compound treatment 280820.0 -363000.0 -0.97 263450.0 -328000.0 -0.9 -1.3226 -0.9993 3068275 PK04_096051 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C08 compound treatment 487520.0 -157000.0 -0.42 508720.0 -82500.0 -0.23 -0.456 -0.9585 3186560 PK04_096052 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C09 compound treatment 361760.0 -282000.0 -0.75 386030.0 -205000.0 -0.56 -0.9317 -0.9897 3068147 PK04_096053 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C10 compound treatment 727850.0 83700.0 0.22 413410.0 -178000.0 -0.49 -0.1872 -0.3486 3186976 PK04_096054 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C11 mock treatment 378180.0 -266000.0 -0.71 517980.0 -73200.0 -0.2 -0.6446 -0.8729 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C12 mock treatment 756480.0 112000.0 0.3 572640.0 -18600.0 -0.05 0.176 0.5785 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C13 compound treatment 573250.0 -70900.0 -0.19 675300.0 84100.0 0.23 0.0293 0.098 3186974 PK04_096055 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C14 compound treatment 684190.0 40000.0 0.11 517680.0 -73500.0 -0.2 -0.0672 -0.2942 3186876 PK04_096056 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C15 mock treatment 694400.0 50200.0 0.13 674680.0 83500.0 0.23 0.2569 0.9675 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C16 mock treatment 538750.0 -105000.0 -0.28 402440.0 -189000.0 -0.52 -0.5656 -0.9589 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C17 compound treatment 606400.0 -37800.0 -0.1 292860.0 -298000.0 -0.82 -0.6506 -0.7883 3186553 PK04_096057 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C18 compound treatment 707040.0 62900.0 0.17 800000.0 209000.0 0.57 0.524 0.8774 3186634 PK04_096058 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C19 compound treatment 576970.0 -67200.0 -0.18 608050.0 16800.0 0.05 -0.0943 -0.5085 3186638 PK04_096059 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C20 compound treatment 631600.0 -12600.0 -0.03 635310.0 44100.0 0.12 0.0618 0.4922 3068219 PK04_096060 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C21 compound treatment 629600.0 -14600.0 -0.04 311880.0 -279000.0 -0.77 -0.5698 -0.7421 3068151 PK04_096061 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C22 compound treatment 394670.0 -250000.0 -0.67 526330.0 -64900.0 -0.18 -0.5972 -0.8657 3068158 PK04_096062 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C23 compound treatment 240000.0 -404000.0 -1.08 259850.0 -331000.0 -0.91 -1.4067 -0.9964 3186800 PK04_096063 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 C24 compound treatment 277920.0 -366000.0 -0.98 245630.0 -346000.0 -0.95 -1.3626 -0.9999 3068376 PK04_096064 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D01 compound treatment 791050.0 147000.0 0.39 775810.0 185000.0 0.51 0.6357 0.992 3068407 PK04_096065 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D02 compound treatment 662420.0 18200.0 0.05 452120.0 -139000.0 -0.38 -0.2356 -0.6119 3187117 PK04_096066 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D03 compound treatment 325140.0 -319000.0 -0.85 611260.0 20000.0 0.06 -0.5637 -0.6601 3187274 PK04_096067 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D04 compound treatment 634970.0 -9210.0 -0.02 554080.0 -37100.0 -0.1 -0.0895 -0.8532 3068858 PK04_096068 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C=C)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D05 compound treatment 535790.0 -108000.0 -0.29 718590.0 127000.0 0.35 0.0426 0.0937 3187075 PK04_096069 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D06 compound treatment 620610.0 -23600.0 -0.06 550000.0 -41200.0 -0.11 -0.1245 -0.9617 3187118 PK04_096070 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D07 compound treatment 532890.0 -111000.0 -0.3 733760.0 143000.0 0.39 0.0665 0.1354 3068634 PK04_096071 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D08 compound treatment 461520.0 -183000.0 -0.49 328590.0 -263000.0 -0.72 -0.8548 -0.9819 3068859 PK04_096072 OCc1ccc(cc1)c2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D09 compound treatment 232760.0 -411000.0 -1.1 222110.0 -369000.0 -1.01 -1.4936 -0.9992 3067975 PK04_096073 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D10 compound treatment 711220.0 67000.0 0.18 734130.0 143000.0 0.39 0.404 0.9369 3068860 PK04_096074 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D11 mock treatment 876750.0 233000.0 0.62 640930.0 49700.0 0.14 0.5357 0.8424 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D12 mock treatment 629960.0 -14200.0 -0.04 771730.0 181000.0 0.5 0.3236 0.651 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D13 compound treatment 431730.0 -212000.0 -0.57 737500.0 146000.0 0.4 -0.1173 -0.1687 3187429 PK04_096075 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D14 compound treatment 562200.0 -82000.0 -0.22 536380.0 -54800.0 -0.15 -0.2613 -0.9833 3187119 PK04_096076 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D15 mock treatment 579610.0 -64600.0 -0.17 818450.0 227000.0 0.62 0.3192 0.4931 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D16 mock treatment 664830.0 20600.0 0.06 785880.0 195000.0 0.53 0.4169 0.776 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D17 compound treatment 575080.0 -69100.0 -0.18 469540.0 -122000.0 -0.33 -0.3667 -0.9609 3187348 PK04_096077 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D18 compound treatment 831470.0 187000.0 0.5 229180.0 -362000.0 -0.99 -0.3491 -0.3137 3068861 PK04_096078 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C4CC4)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D19 compound treatment 397610.0 -247000.0 -0.66 280850.0 -310000.0 -0.85 -1.0682 -0.9919 3187354 PK04_096079 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D20 compound treatment 742440.0 98300.0 0.26 695530.0 104000.0 0.29 0.3881 0.9991 3187120 PK04_096080 OCc1ccc(cc1)c2cc[n+](Cc3sc4ccccc4c3Cl)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D21 compound treatment 670120.0 25900.0 0.07 346360.0 -245000.0 -0.67 -0.4264 -0.6309 3187433 PK04_096081 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D22 compound treatment 608540.0 -35600.0 -0.1 402400.0 -189000.0 -0.52 -0.4339 -0.8232 3068862 PK04_096082 COc1cc2CCN(C)C(C)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D23 compound treatment 670590.0 26400.0 0.07 316540.0 -275000.0 -0.75 -0.4834 -0.6382 3068462 PK04_096083 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 D24 compound treatment 380190.0 -264000.0 -0.71 258820.0 -332000.0 -0.91 -1.1439 -0.9919 3187121 PK04_096084 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E01 mock treatment 859360.0 215000.0 0.57 556210.0 -35000.0 -0.1 0.3384 0.5808 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E02 mock treatment 910020.0 266000.0 0.71 755450.0 164000.0 0.45 0.8209 0.976 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E03 compound treatment 234400.0 -410000.0 -1.09 319910.0 -271000.0 -0.74 -1.3006 -0.9824 3186708 PK04_096085 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E04 compound treatment 266460.0 -378000.0 -1.01 335310.0 -256000.0 -0.7 -1.2102 -0.9844 3186710 PK04_096086 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E05 compound treatment 666760.0 22600.0 0.06 535570.0 -55700.0 -0.15 -0.0654 -0.3981 3186888 PK04_096087 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E06 compound treatment 601120.0 -43100.0 -0.12 471450.0 -120000.0 -0.33 -0.3138 -0.9009 3186565 PK04_096088 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E07 compound treatment 730010.0 85800.0 0.23 399810.0 -191000.0 -0.53 -0.2095 -0.3654 3186983 PK04_096089 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E08 compound treatment 751360.0 107000.0 0.29 408890.0 -182000.0 -0.5 -0.1515 -0.2628 3067581 PK04_096090 CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E09 mock treatment 691650.0 47500.0 0.13 561820.0 -29400.0 -0.08 0.0326 0.2168 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E10 mock treatment 886590.0 242000.0 0.65 847960.0 257000.0 0.7 0.9562 0.9991 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E11 compound treatment 309440.0 -335000.0 -0.89 343520.0 -248000.0 -0.68 -1.1131 -0.9909 3186717 PK04_096091 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E12 compound treatment 350460.0 -294000.0 -0.78 617940.0 26700.0 0.07 -0.5029 -0.6382 3068221 PK04_096092 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E13 compound treatment 276480.0 -368000.0 -0.98 272270.0 -319000.0 -0.88 -1.3136 -0.9984 3068273 PK04_096093 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E14 compound treatment 791060.0 147000.0 0.39 517940.0 -73300.0 -0.2 0.1351 0.3065 3068377 PK04_096094 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E15 compound treatment 478580.0 -166000.0 -0.44 374630.0 -217000.0 -0.59 -0.7332 -0.9894 3068408 PK04_096095 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E16 compound treatment 613010.0 -31200.0 -0.08 717140.0 126000.0 0.35 0.1856 0.5219 3186635 PK04_096096 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E17 mock treatment 500220.0 -144000.0 -0.38 732030.0 141000.0 0.39 0.0015 0.0027 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E18 mock treatment 340000.0 -304000.0 -0.81 274720.0 -317000.0 -0.87 -1.1889 -0.9994 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E19 compound treatment 263330.0 -381000.0 -1.02 300750.0 -290000.0 -0.8 -1.2832 -0.9927 3186791 PK04_096097 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E20 compound treatment 529570.0 -115000.0 -0.31 423860.0 -167000.0 -0.46 -0.5414 -0.9805 3068233 PK04_096098 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E21 compound treatment 254370.0 -390000.0 -1.04 220250.0 -371000.0 -1.02 -1.4564 -0.9999 3186719 PK04_096099 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)Sc6ccc(C)cc6)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E22 compound treatment 304910.0 -339000.0 -0.91 246600.0 -345000.0 -0.95 -1.3098 -0.9998 3186789 PK04_096100 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E23 compound treatment 229730.0 -414000.0 -1.11 278050.0 -313000.0 -0.86 -1.3907 -0.9922 3186803 PK04_096101 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 E24 compound treatment 262080.0 -382000.0 -1.02 282490.0 -309000.0 -0.85 -1.321 -0.9957 3186711 PK04_096102 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F01 mock treatment 614850.0 -29300.0 -0.08 727470.0 136000.0 0.37 0.2091 0.5471 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F02 mock treatment 766720.0 123000.0 0.33 600110.0 8890.0 0.02 0.2487 0.7577 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F03 compound treatment 391260.0 -253000.0 -0.68 782750.0 192000.0 0.53 -0.1059 -0.1237 3068521 PK04_096103 CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F04 compound treatment 468960.0 -175000.0 -0.47 497800.0 -93400.0 -0.26 -0.5123 -0.9599 3187122 PK04_096104 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F05 compound treatment 271620.0 -373000.0 -1.0 404050.0 -187000.0 -0.51 -1.067 -0.9527 3068461 PK04_096105 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F06 compound treatment 305840.0 -338000.0 -0.9 486970.0 -104000.0 -0.29 -0.8414 -0.8876 3068863 PK04_096106 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F07 compound treatment 355790.0 -288000.0 -0.77 363540.0 -228000.0 -0.63 -0.9867 -0.9946 3187077 PK04_096107 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F08 compound treatment 454400.0 -190000.0 -0.51 569790.0 -21400.0 -0.06 -0.4 -0.7839 3187123 PK04_096108 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CN5CCCC5)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F09 mock treatment 754850.0 111000.0 0.3 456520.0 -135000.0 -0.37 -0.0525 -0.1108 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F10 mock treatment 719070.0 74900.0 0.2 690200.0 99000.0 0.27 0.3336 0.9886 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F11 compound treatment 644020.0 -160.0 0.0 662190.0 71000.0 0.19 0.1375 0.7055 3187438 PK04_096109 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F12 compound treatment 311410.0 -333000.0 -0.89 706660.0 115000.0 0.32 -0.4044 -0.4285 3187124 PK04_096110 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OC)c3ccc(CO)cc3)c4cccs4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F13 compound treatment 244610.0 -400000.0 -1.07 282110.0 -309000.0 -0.85 -1.3547 -0.9936 3068559 PK04_096111 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F14 compound treatment 715200.0 71000.0 0.19 552550.0 -38700.0 -0.11 0.0591 0.2717 3068864 PK04_096112 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F15 compound treatment 288680.0 -356000.0 -0.95 316800.0 -274000.0 -0.75 -1.2042 -0.9934 3186801 PK04_096113 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F16 compound treatment 371720.0 -272000.0 -0.73 427490.0 -164000.0 -0.45 -0.8324 -0.9732 3187125 PK04_096114 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F17 mock treatment 866580.0 222000.0 0.59 918020.0 327000.0 0.9 1.0545 0.98 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F18 mock treatment 453530.0 -191000.0 -0.51 747100.0 156000.0 0.43 -0.0575 -0.0864 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F19 compound treatment 304280.0 -340000.0 -0.91 267760.0 -323000.0 -0.89 -1.2699 -0.9999 3186718 PK04_096115 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NC6CC6)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F20 compound treatment 337660.0 -307000.0 -0.82 299640.0 -292000.0 -0.8 -1.145 -0.9999 3068865 PK04_096116 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4cccs4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F21 compound treatment 245360.0 -399000.0 -1.07 269410.0 -322000.0 -0.88 -1.378 -0.9957 3067569 PK04_096117 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F22 compound treatment 659840.0 15700.0 0.04 561600.0 -29600.0 -0.08 -0.0279 -0.3054 3187126 PK04_096118 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C=C)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F23 compound treatment 292290.0 -352000.0 -0.94 289320.0 -302000.0 -0.83 -1.2507 -0.998 3068643 PK04_096119 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 F24 compound treatment 528690.0 -115000.0 -0.31 609920.0 18700.0 0.05 -0.1818 -0.5814 3187127 PK04_096120 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)c5cccs5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G01 compound treatment 370770.0 -273000.0 -0.73 826720.0 235000.0 0.65 -0.0592 -0.0607 3186434 PK04_096121 CN(C)CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G02 compound treatment 370120.0 -274000.0 -0.73 853780.0 263000.0 0.72 -0.0079 -0.0077 3067602 PK04_096122 CC(C)N1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G03 mock treatment 546210.0 -98000.0 -0.26 539810.0 -51400.0 -0.14 -0.2848 -0.958 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G04 mock treatment 807240.0 163000.0 0.44 654450.0 63200.0 0.17 0.4307 0.9187 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G05 compound treatment 350030.0 -294000.0 -0.79 194310.0 -397000.0 -1.09 -1.3261 -0.9871 3068238 PK04_096123 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)Sc5ccc(C)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G06 compound treatment 290290.0 -354000.0 -0.95 286240.0 -305000.0 -0.84 -1.2604 -0.9982 3068315 PK04_096124 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G07 compound treatment 273340.0 -371000.0 -0.99 300600.0 -291000.0 -0.8 -1.2646 -0.9942 3186805 PK04_096125 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G08 compound treatment 281140.0 -363000.0 -0.97 331100.0 -260000.0 -0.71 -1.1906 -0.9887 3186712 PK04_096126 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G09 compound treatment 634670.0 -9510.0 -0.03 610950.0 19700.0 0.05 0.0203 0.34 3068360 PK04_096127 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G10 compound treatment 812320.0 168000.0 0.45 434480.0 -157000.0 -0.43 0.0133 0.0214 3186431 PK04_096128 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N([C@@H]3c4ccc(CO)cc24)C5CCCCC5)c6ccc(cc6)[N+](=O)[O-])cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G11 compound treatment 390240.0 -254000.0 -0.68 378560.0 -213000.0 -0.58 -0.8924 -0.9972 3186642 PK04_096129 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G12 compound treatment 401700.0 -242000.0 -0.65 322320.0 -269000.0 -0.74 -0.98 -0.9979 3068326 PK04_096130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G13 compound treatment 836580.0 192000.0 0.51 210320.0 -381000.0 -1.05 -0.3761 -0.3228 3186484 PK04_096131 CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G14 compound treatment 619370.0 -24800.0 -0.07 453010.0 -138000.0 -0.38 -0.3152 -0.8182 3068146 PK04_096132 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G15 compound treatment 484530.0 -160000.0 -0.43 602000.0 10800.0 0.03 -0.2806 -0.6565 3068195 PK04_096133 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C6CC6)C4=O)c7ccccc7C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G16 compound treatment 319010.0 -325000.0 -0.87 296160.0 -295000.0 -0.81 -1.1869 -0.9994 3068279 PK04_096134 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G17 compound treatment 612360.0 -31800.0 -0.08 301020.0 -290000.0 -0.8 -0.6235 -0.7781 3068328 PK04_096135 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G18 compound treatment 262430.0 -382000.0 -1.02 306680.0 -285000.0 -0.78 -1.2734 -0.9913 3068311 PK04_096136 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G19 mock treatment 330950.0 -313000.0 -0.84 317010.0 -274000.0 -0.75 -1.1239 -0.9986 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G20 mock treatment 476820.0 -167000.0 -0.45 439160.0 -152000.0 -0.42 -0.6113 -0.9994 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G21 compound treatment 251040.0 -393000.0 -1.05 219590.0 -372000.0 -1.02 -1.464 -0.9999 3068284 PK04_096137 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G22 compound treatment 344100.0 -300000.0 -0.8 415960.0 -175000.0 -0.48 -0.907 -0.9702 3186501 PK04_096138 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G23 compound treatment 510190.0 -134000.0 -0.36 537490.0 -53700.0 -0.15 -0.3574 -0.9232 3186555 PK04_096139 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 G24 compound treatment 448270.0 -196000.0 -0.52 256670.0 -335000.0 -0.92 -1.0195 -0.9644 3186877 PK04_096140 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H01 compound treatment 296110.0 -348000.0 -0.93 800570.0 209000.0 0.57 -0.251 -0.2296 3186629 PK04_096141 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H02 compound treatment 536070.0 -108000.0 -0.29 410360.0 -181000.0 -0.5 -0.5553 -0.9667 3068866 PK04_096142 OCc1ccc(cc1)c2cc[n+](Cc3cc4OCOc4cc3Br)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H03 mock treatment 536410.0 -108000.0 -0.29 352250.0 -239000.0 -0.66 -0.6675 -0.9316 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H04 mock treatment 456650.0 -188000.0 -0.5 280550.0 -311000.0 -0.85 -0.9573 -0.9678 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H05 compound treatment 396000.0 -248000.0 -0.66 726960.0 136000.0 0.37 -0.2052 -0.2699 3186432 PK04_096143 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H06 compound treatment 247440.0 -397000.0 -1.06 328020.0 -263000.0 -0.72 -1.2603 -0.9826 3068867 PK04_096144 OCc1ccc(cc1)c2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H07 compound treatment 333350.0 -311000.0 -0.83 702470.0 111000.0 0.31 -0.3711 -0.4195 3187128 PK04_096145 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3C4CC5CC(C4)CC3C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H08 compound treatment 649230.0 5050.0 0.01 288320.0 -303000.0 -0.83 -0.5785 -0.6955 3068868 PK04_096146 COc1cc2CC[N+](=Cc2cc1O)Cc3sc4ccccc4c3Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H09 compound treatment 549930.0 -94300.0 -0.25 466880.0 -124000.0 -0.34 -0.4194 -0.9888 3186637 PK04_096147 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H10 compound treatment 414320.0 -230000.0 -0.61 283840.0 -307000.0 -0.84 -1.0309 -0.9878 3187129 PK04_096148 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C4CC4)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H11 compound treatment 792230.0 148000.0 0.4 685010.0 93800.0 0.26 0.4617 0.9784 3187130 PK04_096149 CC1(C)OB(OC1(C)C)/C=C\CC(OC(=O)c2ccncc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H12 compound treatment 814720.0 171000.0 0.46 255450.0 -336000.0 -0.92 -0.3297 -0.3207 3187131 PK04_096150 C[n+]1ccc(cc1)c2ccc(CO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H13 compound treatment 770080.0 126000.0 0.34 378800.0 -212000.0 -0.58 -0.1746 -0.2593 3068898 PK04_096151 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)C)c2ccccc2)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H14 compound treatment 568640.0 -75500.0 -0.2 341200.0 -250000.0 -0.69 -0.628 -0.8778 3187132 PK04_096152 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H15 compound treatment 223400.0 -421000.0 -1.12 304070.0 -287000.0 -0.79 -1.3522 -0.985 3187133 PK04_096153 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)C)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H16 compound treatment 294340.0 -350000.0 -0.93 443910.0 -147000.0 -0.4 -0.9467 -0.9298 3187134 PK04_096154 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C2)c6cccs6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H17 compound treatment 433570.0 -211000.0 -0.56 292550.0 -299000.0 -0.82 -0.9776 -0.9831 3068899 PK04_096155 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)c3ccncc3)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H18 compound treatment 333700.0 -310000.0 -0.83 277760.0 -313000.0 -0.86 -1.1949 -0.9998 3068900 PK04_096156 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C5CC5)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H19 mock treatment 486410.0 -158000.0 -0.42 725040.0 134000.0 0.37 -0.0382 -0.0683 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H20 mock treatment 653170.0 8990.0 0.02 430910.0 -160000.0 -0.44 -0.2942 -0.6675 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H21 compound treatment 346990.0 -297000.0 -0.79 199590.0 -392000.0 -1.08 -1.3216 -0.9889 3187204 PK04_096157 CC(C)(C)OC(=O)COc1cccc(c1)C(=O)CCN2CCOCC2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H22 compound treatment 808570.0 164000.0 0.44 341310.0 -250000.0 -0.69 -0.1747 -0.2144 3187205 PK04_096158 OCCCc1cc[n+](Cc2cc3OCOc3cc2Br)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H23 compound treatment 261820.0 -382000.0 -1.02 215470.0 -376000.0 -1.03 -1.4516 -1.0 3068901 PK04_096159 COc1ccc(/C=C/C(=O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 H24 compound treatment 619840.0 -24300.0 -0.07 414840.0 -176000.0 -0.48 -0.3884 -0.7949 3187206 PK04_096160 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I01 compound treatment 262630.0 -382000.0 -1.02 298900.0 -292000.0 -0.8 -1.2881 -0.993 3186796 PK04_096161 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I02 compound treatment 593830.0 -50400.0 -0.13 797340.0 206000.0 0.57 0.305 0.5245 3186628 PK04_096162 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I03 compound treatment 440330.0 -204000.0 -0.54 216660.0 -375000.0 -1.03 -1.1121 -0.9558 3186882 PK04_096163 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I04 compound treatment 222980.0 -421000.0 -1.13 243000.0 -348000.0 -0.96 -1.4715 -0.9967 3186797 PK04_096164 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I05 mock treatment 386840.0 -257000.0 -0.69 495130.0 -96100.0 -0.26 -0.6726 -0.9135 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I06 mock treatment 559200.0 -85000.0 -0.23 472580.0 -119000.0 -0.33 -0.3908 -0.9844 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I07 compound treatment 446440.0 -198000.0 -0.53 570470.0 -20800.0 -0.06 -0.4137 -0.7789 3186430 PK04_096165 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(C5CC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I08 compound treatment 794630.0 150000.0 0.4 478170.0 -113000.0 -0.31 0.0647 0.1274 3186557 PK04_096166 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I09 compound treatment 569120.0 -75100.0 -0.2 403920.0 -187000.0 -0.51 -0.5054 -0.9157 3186558 PK04_096167 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I10 compound treatment 298250.0 -346000.0 -0.92 264720.0 -327000.0 -0.9 -1.2872 -0.9999 3068320 PK04_096168 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I11 compound treatment 775200.0 131000.0 0.35 723770.0 133000.0 0.36 0.5048 0.9998 3068364 PK04_096169 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I12 compound treatment 464750.0 -179000.0 -0.48 560060.0 -31200.0 -0.09 -0.3994 -0.8204 3186489 PK04_096170 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I13 compound treatment 585770.0 -58400.0 -0.16 619920.0 28700.0 0.08 -0.0546 -0.3124 3186807 PK04_096171 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I14 compound treatment 324000.0 -320000.0 -0.86 312280.0 -279000.0 -0.77 -1.1462 -0.9985 3068281 PK04_096172 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I15 compound treatment 847040.0 203000.0 0.54 650920.0 59700.0 0.16 0.499 0.8816 3186567 PK04_096173 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I16 compound treatment 516850.0 -127000.0 -0.34 699460.0 108000.0 0.3 -0.0304 -0.0672 3068410 PK04_096174 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I17 compound treatment 412120.0 -232000.0 -0.62 663690.0 72500.0 0.2 -0.2976 -0.4572 3186973 PK04_096175 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I18 compound treatment 307460.0 -337000.0 -0.9 325140.0 -266000.0 -0.73 -1.1525 -0.9947 3068148 PK04_096176 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I19 compound treatment 328200.0 -316000.0 -0.84 426180.0 -165000.0 -0.45 -0.9172 -0.9575 3068239 PK04_096177 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I20 compound treatment 348400.0 -296000.0 -0.79 286600.0 -305000.0 -0.84 -1.15 -0.9996 3068268 PK04_096178 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I21 mock treatment 479200.0 -165000.0 -0.44 464990.0 -126000.0 -0.35 -0.5566 -0.9929 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I22 mock treatment 377510.0 -267000.0 -0.71 454770.0 -136000.0 -0.37 -0.7685 -0.955 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I23 compound treatment 472680.0 -172000.0 -0.46 454880.0 -136000.0 -0.37 -0.5886 -0.995 3186564 PK04_096179 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 I24 compound treatment 460860.0 -183000.0 -0.49 410090.0 -181000.0 -0.5 -0.6979 -1.0 3068366 PK04_096180 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J01 compound treatment 21390.0 -623000.0 -1.66 40070.0 -551000.0 -1.51 -2.2462 -0.9989 1230870 PK04_096181 Oc1cccc(c1)C(=O)CCN2CCOCC2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J02 compound treatment 306560.0 -338000.0 -0.9 432040.0 -159000.0 -0.44 -0.9467 -0.9447 3187207 PK04_096182 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)C3CC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J03 compound treatment 885660.0 241000.0 0.64 789450.0 198000.0 0.54 0.8409 0.9964 3068902 PK04_096183 COc1ccc(CC[C@H](O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J04 compound treatment 478720.0 -165000.0 -0.44 526720.0 -64500.0 -0.18 -0.4377 -0.9194 3187208 PK04_096184 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J05 mock treatment 492030.0 -152000.0 -0.41 279050.0 -312000.0 -0.86 -0.8934 -0.9419 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J06 mock treatment 298770.0 -345000.0 -0.92 772660.0 181000.0 0.5 -0.3001 -0.2863 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J07 compound treatment 618630.0 -25600.0 -0.07 411280.0 -180000.0 -0.49 -0.3976 -0.7972 3187209 PK04_096185 CCCN1C(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@H](N2C1=O)c5cccc(O)c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J08 compound treatment 606180.0 -38000.0 -0.1 376010.0 -215000.0 -0.59 -0.4896 -0.8166 3068903 PK04_096186 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J09 compound treatment 824020.0 180000.0 0.48 323200.0 -268000.0 -0.74 -0.1807 -0.2056 1032549 PK04_096187 CCOC(=O)C1CCCCN1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J10 compound treatment 633390.0 -10800.0 -0.03 544240.0 -47000.0 -0.13 -0.1116 -0.8443 3187210 PK04_096188 COc1cc2CCN(C)C(C=C)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J11 compound treatment 624050.0 -20100.0 -0.05 698930.0 108000.0 0.3 0.1711 0.5692 3187211 PK04_096189 CCOC(=O)[C@@H]1CCCCN1C(=O)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J12 compound treatment 752690.0 109000.0 0.29 704830.0 114000.0 0.31 0.4255 0.9993 3187212 PK04_096190 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4ccc(CN5CCCC5)cc4)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J13 compound treatment 495600.0 -149000.0 -0.4 496390.0 -94800.0 -0.26 -0.4647 -0.9791 3068904 PK04_096191 [O-][N+](=O)c1cc(Br)ccc1C(=O)NCc2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J14 compound treatment 338940.0 -305000.0 -0.82 722080.0 131000.0 0.36 -0.3225 -0.3619 3068905 PK04_096192 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C=C)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J15 compound treatment 684730.0 40500.0 0.11 296600.0 -295000.0 -0.81 -0.4954 -0.607 3187213 PK04_096193 CC(=O)Nc1cc(Br)ccc1C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J16 compound treatment 368750.0 -275000.0 -0.74 238190.0 -353000.0 -0.97 -1.2055 -0.9907 3187214 PK04_096194 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5cccs5)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J17 compound treatment 608750.0 -35400.0 -0.09 636890.0 45700.0 0.13 0.0217 0.1384 3068906 PK04_096195 CC(=O)Nc1cc(Br)ccc1C(=O)NCc2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J18 compound treatment 620160.0 -24000.0 -0.06 427400.0 -164000.0 -0.45 -0.3634 -0.7999 3187215 PK04_096196 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5cccs5)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J19 compound treatment 234610.0 -410000.0 -1.09 309050.0 -282000.0 -0.77 -1.3213 -0.9857 3068907 PK04_096197 Brc1ccc2c(=O)oc(nc2c1)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J20 compound treatment 498590.0 -146000.0 -0.39 479400.0 -112000.0 -0.31 -0.492 -0.9931 3187216 PK04_096198 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4ccc(CN5CCCC5)cc4)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J21 mock treatment 949890.0 306000.0 0.82 447930.0 -143000.0 -0.39 0.2992 0.3301 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J22 mock treatment 802240.0 158000.0 0.42 365390.0 -226000.0 -0.62 -0.1399 -0.1865 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J23 compound treatment 611630.0 -32600.0 -0.09 242810.0 -348000.0 -0.96 -0.7378 -0.7682 3068908 PK04_096199 Nc1cc(Br)ccc1C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 J24 compound treatment 280960.0 -363000.0 -0.97 406570.0 -185000.0 -0.51 -1.0445 -0.9542 3068910 PK04_096200 Oc1ccc2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K01 compound treatment 863590.0 219000.0 0.59 900350.0 309000.0 0.85 1.0145 0.9837 3068198 PK04_096201 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(Cc6ccccc6)C4=O)c7ccccc7C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K02 compound treatment 768640.0 124000.0 0.33 797630.0 206000.0 0.57 0.6358 0.9677 3186870 PK04_096202 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K03 compound treatment 403380.0 -241000.0 -0.64 720520.0 129000.0 0.35 -0.2038 -0.2774 3068155 PK04_096203 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K04 compound treatment 534040.0 -110000.0 -0.29 398410.0 -193000.0 -0.53 -0.5823 -0.9616 3186875 PK04_096204 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K05 compound treatment 597480.0 -46700.0 -0.12 779450.0 188000.0 0.52 0.2772 0.5215 3068359 PK04_096205 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K06 compound treatment 364840.0 -279000.0 -0.75 375630.0 -216000.0 -0.59 -0.9461 -0.9934 3186626 PK04_096206 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(F)(F)F)C4=O)c6ccccc6C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K07 mock treatment 282400.0 -362000.0 -0.97 519280.0 -71900.0 -0.2 -0.8229 -0.8344 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K08 mock treatment 953880.0 310000.0 0.83 779960.0 189000.0 0.52 0.9513 0.9746 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K09 compound treatment 724410.0 80200.0 0.21 508640.0 -82600.0 -0.23 -0.0088 -0.0282 3186869 PK04_096207 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)Sc5ccc(C)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K10 compound treatment 709700.0 65500.0 0.18 417970.0 -173000.0 -0.48 -0.2126 -0.4195 3068235 PK04_096208 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K11 compound treatment 841440.0 197000.0 0.53 868000.0 277000.0 0.76 0.9099 0.984 3186487 PK04_096209 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(Cc7ccccc7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K12 compound treatment 620260.0 -23900.0 -0.06 745700.0 154000.0 0.42 0.2547 0.5939 3068411 PK04_096210 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K13 compound treatment 805690.0 162000.0 0.43 542030.0 -49200.0 -0.14 0.2095 0.4636 3068329 PK04_096211 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K14 compound treatment 991170.0 347000.0 0.93 694560.0 103000.0 0.28 0.856 0.8831 3067608 PK04_096212 COCCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K15 mock treatment 525470.0 -119000.0 -0.32 873880.0 283000.0 0.78 0.3245 0.3871 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K16 mock treatment 897240.0 253000.0 0.68 970460.0 379000.0 1.04 1.2142 0.9781 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K17 compound treatment 881240.0 237000.0 0.63 510400.0 -80800.0 -0.22 0.2908 0.4335 3186979 PK04_096213 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K18 compound treatment 631490.0 -12700.0 -0.03 891620.0 300000.0 0.82 0.5592 0.6775 3186636 PK04_096214 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K19 compound treatment 336450.0 -308000.0 -0.82 313540.0 -278000.0 -0.76 -1.1203 -0.9993 3186793 PK04_096215 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K20 compound treatment 763840.0 120000.0 0.32 939590.0 348000.0 0.96 0.9023 0.8948 3186637 PK04_096216 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K21 compound treatment 444710.0 -199000.0 -0.53 481920.0 -109000.0 -0.3 -0.5889 -0.9631 3067613 PK04_096217 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N(CC4(CC5CC6CC(C5)C4)C6)[C@@H]3c7ccc(CO)cc27)c8ccc(cc8)[N+](=O)[O-])cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K22 compound treatment 659740.0 15600.0 0.04 554240.0 -37000.0 -0.1 -0.0424 -0.3865 3186873 PK04_096218 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K23 mock treatment 594360.0 -49800.0 -0.13 699580.0 108000.0 0.3 0.1163 0.3568 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 K24 mock treatment 815840.0 172000.0 0.46 521490.0 -69700.0 -0.19 0.1888 0.3801 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L01 compound treatment 581010.0 -63200.0 -0.17 904380.0 313000.0 0.86 0.4886 0.5577 3068940 PK04_096219 Cc1nc2cc(Br)ccc2c(=O)o1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L02 compound treatment 622330.0 -21900.0 -0.06 670160.0 78900.0 0.22 0.112 0.4989 3187217 PK04_096220 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L03 compound treatment 857490.0 213000.0 0.57 870980.0 280000.0 0.77 0.946 0.9892 3068941 PK04_096221 CC(C)c1nc2cc(Br)ccc2c(=O)o1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L04 compound treatment 398300.0 -246000.0 -0.66 324000.0 -267000.0 -0.73 -0.9831 -0.9985 3068942 PK04_096222 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L05 compound treatment 805410.0 161000.0 0.43 558670.0 -32600.0 -0.09 0.2413 0.5487 3187218 PK04_096223 Cc1nc2cc(Br)ccc2c(=O)n1Cc3cccc(O)c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L06 compound treatment 595230.0 -49000.0 -0.13 824960.0 234000.0 0.64 0.3613 0.5517 3068943 PK04_096224 COc1cc2CCN(C)C(c3cccs3)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L07 mock treatment 820920.0 177000.0 0.47 669650.0 78400.0 0.22 0.4861 0.9368 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L08 mock treatment 730440.0 86300.0 0.23 800180.0 209000.0 0.57 0.5686 0.9197 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L09 compound treatment 653840.0 9660.0 0.03 625320.0 34100.0 0.09 0.0844 0.8696 3187219 PK04_096225 Oc1cccc(CNC(=O)c2ccc(Br)cc2NC(=O)c3ccccc3)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L10 compound treatment 517650.0 -127000.0 -0.34 540960.0 -50300.0 -0.14 -0.3365 -0.9219 3187220 PK04_096226 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L11 compound treatment 548320.0 -95900.0 -0.26 709570.0 118000.0 0.32 0.0487 0.1177 3068944 PK04_096227 Oc1cccc(Cn2c(nc3cc(Br)ccc3c2=O)c4ccccc4)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L12 compound treatment 609280.0 -34900.0 -0.09 699760.0 109000.0 0.3 0.1448 0.4637 3187221 PK04_096228 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L13 compound treatment 699200.0 55000.0 0.15 570190.0 -21000.0 -0.06 0.0631 0.3996 1980253 PK04_096229 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2)/C#N)c(=O)n(c3ccccc3)n1C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L14 compound treatment 576640.0 -67500.0 -0.18 708210.0 117000.0 0.32 0.0996 0.2702 3068945 PK04_096230 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L15 mock treatment 695060.0 50900.0 0.14 424960.0 -166000.0 -0.46 -0.2267 -0.4759 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L16 mock treatment 604000.0 -40200.0 -0.11 558570.0 -32700.0 -0.09 -0.1393 -0.996 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L17 compound treatment 216330.0 -428000.0 -1.14 180370.0 -411000.0 -1.13 -1.6057 -1.0 3187222 PK04_096231 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L18 compound treatment 513520.0 -131000.0 -0.35 618500.0 27300.0 0.07 -0.1938 -0.543 3187223 PK04_096232 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6cccs6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L19 compound treatment 292120.0 -352000.0 -0.94 204650.0 -387000.0 -1.06 -1.4154 -0.9982 3068946 PK04_096233 Cc1c(NC(=O)/C(=C/C=C/c2ccc(cc2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L20 compound treatment 706140.0 62000.0 0.17 697210.0 106000.0 0.29 0.3228 0.9642 3187224 PK04_096234 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5cccs5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L21 compound treatment 603750.0 -40400.0 -0.11 637820.0 46600.0 0.13 0.0141 0.0842 3068947 PK04_096235 CN(C)c1ccc(/C=C/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L22 compound treatment 276160.0 -368000.0 -0.98 597130.0 5910.0 0.02 -0.6836 -0.6953 3187225 PK04_096236 COc1cc2CCN(C)C(C3CC3)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L23 mock treatment 640450.0 -3730.0 -0.01 761480.0 170000.0 0.47 0.3235 0.6919 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 L24 mock treatment 818880.0 175000.0 0.47 632130.0 40900.0 0.11 0.4094 0.8529 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M01 compound treatment 853560.0 209000.0 0.56 497000.0 -94200.0 -0.26 0.2125 0.3449 3186502 PK04_096237 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M02 compound treatment 331960.0 -312000.0 -0.83 370050.0 -221000.0 -0.61 -1.019 -0.9878 3186497 PK04_096238 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC(C)C)c5ccccc5C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M03 compound treatment 669980.0 25800.0 0.07 805440.0 214000.0 0.59 0.4646 0.7846 3068404 PK04_096239 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M04 compound treatment 335150.0 -309000.0 -0.83 349200.0 -242000.0 -0.66 -1.0535 -0.9942 3186643 PK04_096240 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NC5CC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M05 compound treatment 262400.0 -382000.0 -1.02 257700.0 -334000.0 -0.92 -1.3685 -0.9986 3186723 PK04_096241 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M06 compound treatment 587760.0 -56400.0 -0.15 513000.0 -78200.0 -0.21 -0.2584 -0.985 3186868 PK04_096242 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NC5CC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M07 compound treatment 284930.0 -359000.0 -0.96 281600.0 -310000.0 -0.85 -1.2796 -0.9982 3186798 PK04_096243 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M08 compound treatment 272230.0 -372000.0 -0.99 278530.0 -313000.0 -0.86 -1.3095 -0.9974 3186799 PK04_096244 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M09 mock treatment 520550.0 -124000.0 -0.33 516710.0 -74500.0 -0.2 -0.3781 -0.9735 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M10 mock treatment 741180.0 97000.0 0.26 593250.0 2030.0 0.01 0.1871 0.7221 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M11 compound treatment 530520.0 -114000.0 -0.3 563360.0 -27900.0 -0.08 -0.2688 -0.8584 3186496 PK04_096245 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M12 compound treatment 736990.0 92800.0 0.25 732160.0 141000.0 0.39 0.4489 0.9768 3068379 PK04_096246 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M13 mock treatment 918670.0 274000.0 0.73 351950.0 -239000.0 -0.66 0.0539 0.0548 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M14 mock treatment 382640.0 -262000.0 -0.7 525530.0 -65700.0 -0.18 -0.6215 -0.8614 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M15 compound treatment 702620.0 58400.0 0.16 545770.0 -45500.0 -0.12 0.0221 0.1108 3186488 PK04_096247 CC(C)N1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M16 compound treatment 762300.0 118000.0 0.32 549800.0 -41400.0 -0.11 0.1427 0.4254 3186886 PK04_096248 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M17 compound treatment 409760.0 -234000.0 -0.63 633230.0 42000.0 0.12 -0.3612 -0.5673 3068154 PK04_096249 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M18 compound treatment 709850.0 65700.0 0.18 506080.0 -85100.0 -0.23 -0.0413 -0.1412 3068369 PK04_096250 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCC(F)(F)F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M19 compound treatment 262600.0 -382000.0 -1.02 255840.0 -335000.0 -0.92 -1.3718 -0.9987 3186727 PK04_096251 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M20 compound treatment 743200.0 99000.0 0.26 478460.0 -113000.0 -0.31 -0.0319 -0.0783 3186984 PK04_096252 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M21 compound treatment 419440.0 -225000.0 -0.6 625450.0 34200.0 0.09 -0.358 -0.5892 3068372 PK04_096253 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M22 compound treatment 297150.0 -347000.0 -0.93 311150.0 -280000.0 -0.77 -1.1991 -0.9957 3186721 PK04_096254 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCC(F)(F)F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M23 compound treatment 285380.0 -359000.0 -0.96 319360.0 -272000.0 -0.75 -1.2054 -0.9924 3068316 PK04_096255 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 M24 compound treatment 283650.0 -361000.0 -0.96 298630.0 -293000.0 -0.8 -1.2489 -0.9959 3068283 PK04_096256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N01 compound treatment 858330.0 214000.0 0.57 901450.0 310000.0 0.85 1.0067 0.9812 1694663 PK04_096257 Cc1c(NC(=O)CC#N)c(=O)n(c2ccccc2)n1C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N02 compound treatment 479360.0 -165000.0 -0.44 577530.0 -13700.0 -0.04 -0.3379 -0.7647 3187226 PK04_096258 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C)C=C(CCCO)C=C1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N03 compound treatment 611700.0 -32500.0 -0.09 726820.0 136000.0 0.37 0.2019 0.5282 3068949 PK04_096259 Cc1ccccc1/C=C/C=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N04 compound treatment 839690.0 196000.0 0.52 549920.0 -41300.0 -0.11 0.2891 0.541 3187227 PK04_096260 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2ccc(CN3CCCC3)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N05 compound treatment 655160.0 11000.0 0.03 687400.0 96200.0 0.26 0.2075 0.7808 3068950 PK04_096261 CCOc1ccc(cc1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N06 compound treatment 781530.0 137000.0 0.37 808440.0 217000.0 0.6 0.6811 0.9728 3187228 PK04_096262 Oc1ccc2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N07 compound treatment 887170.0 243000.0 0.65 607790.0 16600.0 0.05 0.4911 0.7548 3068951 PK04_096263 [O-][N+](=O)c1cccc(c1)C2SCC(=O)N2c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N08 compound treatment 704490.0 60300.0 0.16 825090.0 234000.0 0.64 0.5679 0.8579 3187299 PK04_096264 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4cccs4)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N09 mock treatment 851970.0 208000.0 0.56 773320.0 182000.0 0.5 0.746 0.9986 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N10 mock treatment 692920.0 48700.0 0.13 790440.0 199000.0 0.55 0.4788 0.8516 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N11 compound treatment 764750.0 121000.0 0.32 750740.0 160000.0 0.44 0.5374 0.9886 3068985 PK04_096265 Cc1cc(C)cc(c1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N12 compound treatment 808510.0 164000.0 0.44 811110.0 220000.0 0.6 0.7372 0.9877 3187300 PK04_096266 COc1cc2CCN(C)C(c3ccc(CN4CCCC4)cc3)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N13 mock treatment 810140.0 166000.0 0.44 830240.0 239000.0 0.66 0.7775 0.9818 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N14 mock treatment 687270.0 43100.0 0.12 653480.0 62300.0 0.17 0.2022 0.9815 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N15 compound treatment 531300.0 -113000.0 -0.3 534400.0 -56800.0 -0.16 -0.3235 -0.953 3068986 PK04_096267 COc1ccc(/C=C/C=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N16 compound treatment 640350.0 -3830.0 -0.01 549300.0 -41900.0 -0.12 -0.0886 -0.7669 3187301 PK04_096268 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N17 compound treatment 667650.0 23500.0 0.06 495130.0 -96100.0 -0.26 -0.1422 -0.5245 3068987 PK04_096269 Cc1cccc(/C=C/C=O)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N18 compound treatment 657760.0 13600.0 0.04 721060.0 130000.0 0.36 0.2777 0.7751 3068988 PK04_096270 OCCCc1cc[n+](Cc2sc3ccccc3c2Cl)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N19 compound treatment 775690.0 132000.0 0.35 541920.0 -49300.0 -0.14 0.1527 0.4056 3068989 PK04_096271 Cc1ccc(/C=C/C=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N20 compound treatment 417620.0 -227000.0 -0.61 392070.0 -199000.0 -0.55 -0.8145 -0.9987 3187302 PK04_096272 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N21 compound treatment 478560.0 -166000.0 -0.44 431080.0 -160000.0 -0.44 -0.6237 -1.0 3068990 PK04_096273 COc1cccc(/C=C/C=O)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N22 compound treatment 689300.0 45100.0 0.12 319620.0 -272000.0 -0.75 -0.442 -0.5852 3068991 PK04_096274 Oc1ccc2cc[n+](Cc3cc4OCOc4cc3Br)cc2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N23 compound treatment 467150.0 -177000.0 -0.47 452520.0 -139000.0 -0.38 -0.6036 -0.9942 3187303 PK04_096275 Clc1ccccc1/C=C/C=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 N24 compound treatment 667400.0 23200.0 0.06 756390.0 165000.0 0.45 0.3645 0.7964 3187304 PK04_096276 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)C5CC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O01 compound treatment 424900.0 -219000.0 -0.59 565450.0 -25800.0 -0.07 -0.4642 -0.7868 3186631 PK04_096277 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O02 compound treatment 776410.0 132000.0 0.35 782400.0 191000.0 0.52 0.6209 0.9814 3067615 PK04_096278 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c7ccc(cc7)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O03 compound treatment 204350.0 -440000.0 -1.17 250150.0 -341000.0 -0.94 -1.4928 -0.9937 3186715 PK04_096279 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O04 compound treatment 358240.0 -286000.0 -0.76 281030.0 -310000.0 -0.85 -1.1422 -0.9985 3068363 PK04_096280 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O05 compound treatment 270260.0 -374000.0 -1.0 262170.0 -329000.0 -0.9 -1.345 -0.9987 3068310 PK04_096281 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O06 compound treatment 721360.0 77200.0 0.21 603360.0 12100.0 0.03 0.1693 0.8109 3068196 PK04_096282 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCN6CCOCC6)C4=O)c7ccccc7C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O07 compound treatment 253140.0 -391000.0 -1.04 275860.0 -315000.0 -0.87 -1.3508 -0.9957 3068277 PK04_096283 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O08 compound treatment 265170.0 -379000.0 -1.01 276930.0 -314000.0 -0.86 -1.326 -0.9968 3186720 PK04_096284 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O09 compound treatment 637150.0 -7030.0 -0.02 743000.0 152000.0 0.42 0.2814 0.6746 3186632 PK04_096285 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O10 compound treatment 802600.0 158000.0 0.42 674260.0 83000.0 0.23 0.4604 0.9579 3068157 PK04_096286 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(C5CCCCC5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O11 mock treatment 789860.0 146000.0 0.39 692210.0 101000.0 0.28 0.4712 0.9862 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O12 mock treatment 697470.0 53300.0 0.14 672440.0 81200.0 0.22 0.2583 0.9765 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O13 compound treatment 632260.0 -11900.0 -0.03 580890.0 -10300.0 -0.03 -0.0426 -0.9983 3186874 PK04_096287 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O14 compound treatment 738560.0 94400.0 0.25 651010.0 59800.0 0.16 0.2943 0.9784 3068138 PK04_096288 COCCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O15 compound treatment 784640.0 140000.0 0.38 735320.0 144000.0 0.4 0.545 0.9996 3186972 PK04_096289 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O16 compound treatment 375720.0 -268000.0 -0.72 607070.0 15800.0 0.04 -0.4763 -0.663 3186981 PK04_096290 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O17 compound treatment 296500.0 -348000.0 -0.93 291370.0 -300000.0 -0.82 -1.2388 -0.9982 3186709 PK04_096291 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O18 compound treatment 264550.0 -380000.0 -1.01 272070.0 -319000.0 -0.88 -1.3366 -0.9974 3186725 PK04_096292 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O19 compound treatment 290910.0 -353000.0 -0.94 298270.0 -293000.0 -0.8 -1.2359 -0.9968 3068321 PK04_096293 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O20 compound treatment 674580.0 30400.0 0.08 377870.0 -213000.0 -0.59 -0.3568 -0.6033 3068192 PK04_096294 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O21 compound treatment 629760.0 -14400.0 -0.04 504800.0 -86400.0 -0.24 -0.195 -0.8113 3068201 PK04_096295 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O22 compound treatment 373840.0 -270000.0 -0.72 304730.0 -286000.0 -0.79 -1.0667 -0.9991 3068381 PK04_096296 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O23 compound treatment 351280.0 -293000.0 -0.78 477870.0 -113000.0 -0.31 -0.7732 -0.9184 3186880 PK04_096297 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCc6ccccc6)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 O24 compound treatment 829530.0 185000.0 0.5 593700.0 2480.0 0.01 0.3549 0.7168 3186977 PK04_096298 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P01 compound treatment 534350.0 -110000.0 -0.29 352420.0 -239000.0 -0.66 -0.671 -0.9342 3068992 PK04_096299 Cc1c(NC(=O)/C(=C/c2cccc(c2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P02 compound treatment 282190.0 -362000.0 -0.97 469640.0 -122000.0 -0.33 -0.9197 -0.8991 3187305 PK04_096300 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)C2CC2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P03 compound treatment 477350.0 -167000.0 -0.45 493480.0 -97700.0 -0.27 -0.5048 -0.9705 3187306 PK04_096301 COc1cccc(/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P04 compound treatment 612860.0 -31300.0 -0.08 523850.0 -67400.0 -0.18 -0.1899 -0.9357 3068993 PK04_096302 COc1cc2CC[N+](=Cc2cc1O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P05 compound treatment 514010.0 -130000.0 -0.35 368590.0 -223000.0 -0.61 -0.678 -0.9642 3068994 PK04_096303 Cc1c(NC(=O)/C(=C/c2ccccc2Cl)/C#N)c(=O)n(c3ccccc3)n1C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P06 compound treatment 388910.0 -255000.0 -0.68 355740.0 -235000.0 -0.65 -0.9393 -0.9996 3187307 PK04_096304 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4cccs4)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P07 compound treatment 556480.0 -87700.0 -0.23 453690.0 -138000.0 -0.38 -0.4326 -0.9736 3187308 PK04_096305 Cc1c(NC(=O)/C(=C/c2ccc(Cl)cc2)/C#N)c(=O)n(c3ccccc3)n1C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P08 compound treatment 415200.0 -229000.0 -0.61 503730.0 -87500.0 -0.24 -0.6023 -0.9167 3068995 PK04_096306 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3CCCO)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P09 compound treatment 330140.0 -314000.0 -0.84 383150.0 -208000.0 -0.57 -0.997 -0.9825 1972122 PK04_096307 Cc1cc(C)cc(c1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)CC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P10 compound treatment 454820.0 -189000.0 -0.51 341720.0 -250000.0 -0.68 -0.842 -0.9889 3187309 PK04_096308 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)C4CC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P11 mock treatment 353330.0 -291000.0 -0.78 348550.0 -243000.0 -0.67 -1.0204 -0.9971 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P12 mock treatment 345920.0 -298000.0 -0.8 373190.0 -218000.0 -0.6 -0.9866 -0.9901 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P13 compound treatment 210520.0 -434000.0 -1.16 309450.0 -282000.0 -0.77 -1.366 -0.9807 3068996 PK04_096309 Clc1ccc(/C=C/C=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P14 compound treatment 448990.0 -195000.0 -0.52 375330.0 -216000.0 -0.59 -0.7878 -0.998 3187310 PK04_096310 COc1cc2CC[N+](=Cc2cc1O)Cc3cccc(OC(F)(F)F)c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P15 compound treatment 263170.0 -381000.0 -1.02 268500.0 -323000.0 -0.89 -1.3461 -0.9976 3068997 PK04_096311 O=C/C=C/c1ccc2OCOc2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P16 compound treatment 302160.0 -342000.0 -0.91 264370.0 -327000.0 -0.9 -1.2805 -1.0 3187311 PK04_096312 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3ccc(CN4CCCC4)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P17 compound treatment 11240.0 -633000.0 -1.69 34770.0 -556000.0 -1.53 -2.2757 -0.9987 3068998 PK04_096313 O=C/C=C/c1ccc(cc1)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P18 compound treatment 143960.0 -500000.0 -1.34 200320.0 -391000.0 -1.07 -1.7036 -0.9941 3187312 PK04_096314 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P19 compound treatment 158440.0 -486000.0 -1.3 160500.0 -431000.0 -1.18 -1.7536 -0.9989 3187313 PK04_096315 O=C/C=C/c1ccc(\C=C\c2ccccc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P20 compound treatment 298500.0 -346000.0 -0.92 343970.0 -247000.0 -0.68 -1.1329 -0.9886 3187314 PK04_096316 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4cccs4)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P21 compound treatment 265680.0 -379000.0 -1.01 301840.0 -289000.0 -0.79 -1.2766 -0.9929 3069028 PK04_096317 [O-][N+](=O)c1cccc(c1)C2N(C(=O)CS2(=O)=O)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P22 compound treatment 294370.0 -350000.0 -0.93 320100.0 -271000.0 -0.74 -1.187 -0.9937 3187315 PK04_096318 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P23 compound treatment 193020.0 -451000.0 -1.21 232970.0 -358000.0 -0.98 -1.5476 -0.9949 3069029 PK04_096319 CCOc1ccc(cc1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2096 P24 compound treatment 330890.0 -313000.0 -0.84 287300.0 -304000.0 -0.83 -1.1817 -1.0 3187316 PK04_096320 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)C3CC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A01 compound treatment 715920.0 116000.0 0.31 728050.0 179000.0 0.49 0.5671 0.9749 2141518 PK04_097001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A02 compound treatment 546350.0 -53700.0 -0.14 683630.0 135000.0 0.37 0.1606 0.404 2141905 PK04_097002 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A03 compound treatment 297080.0 -303000.0 -0.81 367360.0 -181000.0 -0.5 -0.9241 -0.9727 2141091 PK04_097003 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A04 compound treatment 320860.0 -279000.0 -0.75 304120.0 -244000.0 -0.67 -1.002 -0.9986 2141692 PK04_097004 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A05 compound treatment 631850.0 31800.0 0.08 675840.0 127000.0 0.35 0.307 0.854 2141533 PK04_097005 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A06 compound treatment 79860.0 -520000.0 -1.39 57040.0 -492000.0 -1.35 -1.9368 -0.9999 2141714 PK04_097006 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A07 compound treatment 462260.0 -138000.0 -0.37 517690.0 -30900.0 -0.08 -0.3203 -0.8479 2141463 PK04_097007 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A08 compound treatment 591690.0 -8410.0 -0.02 518240.0 -30400.0 -0.08 -0.0748 -0.8667 2141076 PK04_097008 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A09 compound treatment 347050.0 -253000.0 -0.68 337940.0 -211000.0 -0.58 -0.8869 -0.997 2141109 PK04_097009 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A10 compound treatment 582410.0 -17700.0 -0.05 362350.0 -186000.0 -0.51 -0.395 -0.7692 2141546 PK04_097010 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A11 compound treatment 706090.0 106000.0 0.28 613050.0 64400.0 0.18 0.3253 0.9744 2141079 PK04_097011 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A12 compound treatment 586720.0 -13400.0 -0.04 547170.0 -1430.0 0.0 -0.028 -0.7803 2141141 PK04_097012 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A13 mock treatment 417790.0 -182000.0 -0.49 336750.0 -212000.0 -0.58 -0.7556 -0.9961 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A14 mock treatment 383550.0 -217000.0 -0.58 764270.0 216000.0 0.59 0.0097 0.0117 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A15 compound treatment 282880.0 -317000.0 -0.85 346100.0 -203000.0 -0.56 -0.9922 -0.9791 2141882 PK04_097013 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A16 compound treatment 434080.0 -166000.0 -0.44 420350.0 -128000.0 -0.35 -0.5625 -0.9935 2141936 PK04_097014 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A17 compound treatment 505440.0 -94700.0 -0.25 490720.0 -57900.0 -0.16 -0.2911 -0.975 2141372 PK04_097015 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A18 compound treatment 639130.0 39000.0 0.1 389880.0 -159000.0 -0.44 -0.2344 -0.5232 2141092 PK04_097016 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A19 compound treatment 435840.0 -164000.0 -0.44 456730.0 -91900.0 -0.25 -0.4886 -0.9655 2141344 PK04_097017 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A20 compound treatment 427360.0 -173000.0 -0.46 401620.0 -147000.0 -0.4 -0.6116 -0.9978 2141115 PK04_097018 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A21 compound treatment 473540.0 -127000.0 -0.34 676500.0 128000.0 0.35 0.0093 0.019 2141570 PK04_097019 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A22 compound treatment 306910.0 -293000.0 -0.78 354570.0 -194000.0 -0.53 -0.9304 -0.9824 2141549 PK04_097020 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A23 compound treatment 390080.0 -210000.0 -0.56 331560.0 -217000.0 -0.6 -0.818 -0.9995 2141876 PK04_097021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 A24 compound treatment 657770.0 57700.0 0.15 312720.0 -236000.0 -0.65 -0.349 -0.5243 2141753 PK04_097022 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B01 compound treatment 398240.0 -202000.0 -0.54 449800.0 -98800.0 -0.27 -0.573 -0.9495 2141940 PK04_097023 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B02 compound treatment 377390.0 -223000.0 -0.59 714620.0 166000.0 0.46 -0.0983 -0.1312 2142685 PK04_097024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B03 compound treatment 580860.0 -19200.0 -0.05 580690.0 32100.0 0.09 0.026 0.2545 2141335 PK04_097025 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B04 compound treatment 496960.0 -103000.0 -0.28 648020.0 99400.0 0.27 -0.0018 -0.0046 2143933 PK04_097026 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B05 compound treatment 842450.0 242000.0 0.65 612100.0 63500.0 0.17 0.581 0.8667 2141445 PK04_097027 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B06 compound treatment 429940.0 -170000.0 -0.45 597180.0 48600.0 0.13 -0.2271 -0.4794 2144925 PK04_097028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B07 compound treatment 385880.0 -214000.0 -0.57 362440.0 -186000.0 -0.51 -0.766 -0.9984 2141881 PK04_097029 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B08 compound treatment 374590.0 -226000.0 -0.6 527960.0 -20600.0 -0.06 -0.466 -0.7702 2144289 PK04_097030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B09 compound treatment 379170.0 -221000.0 -0.59 403010.0 -146000.0 -0.4 -0.6999 -0.982 2141150 PK04_097031 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B10 compound treatment 511430.0 -88700.0 -0.24 490260.0 -58300.0 -0.16 -0.2807 -0.9819 2144633 PK04_097032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B11 compound treatment 680570.0 80500.0 0.21 516000.0 -32600.0 -0.09 0.0887 0.3809 2141161 PK04_097033 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B12 compound treatment 479480.0 -121000.0 -0.32 480890.0 -67700.0 -0.19 -0.3593 -0.9659 2144765 PK04_097034 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B13 mock treatment 704050.0 104000.0 0.28 633410.0 84800.0 0.23 0.361 0.9962 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B14 mock treatment 846240.0 246000.0 0.66 664390.0 116000.0 0.32 0.6897 0.9444 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B15 compound treatment 416210.0 -184000.0 -0.49 685280.0 137000.0 0.38 -0.082 -0.1326 2141135 PK04_097035 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B16 compound treatment 320400.0 -280000.0 -0.75 416550.0 -132000.0 -0.36 -0.7846 -0.9449 2144753 PK04_097036 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B17 compound treatment 391100.0 -209000.0 -0.56 674500.0 126000.0 0.35 -0.1503 -0.229 2141225 PK04_097037 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B18 compound treatment 172020.0 -428000.0 -1.14 233840.0 -315000.0 -0.86 -1.4195 -0.9905 2144045 PK04_097038 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B19 compound treatment 730770.0 131000.0 0.35 562770.0 14200.0 0.04 0.2743 0.7811 2141420 PK04_097039 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B20 compound treatment 665440.0 65300.0 0.17 547240.0 -1360.0 0.0 0.1208 0.6918 2144377 PK04_097040 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B21 compound treatment 837570.0 237000.0 0.63 408530.0 -140000.0 -0.38 0.1766 0.2381 2141808 PK04_097041 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B22 compound treatment 560740.0 -39400.0 -0.11 433620.0 -115000.0 -0.32 -0.2976 -0.8943 2143265 PK04_097042 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B23 compound treatment 477960.0 -122000.0 -0.33 576480.0 27900.0 0.08 -0.1766 -0.5269 2141931 PK04_097043 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 B24 compound treatment 601490.0 1390.0 0.0 366270.0 -182000.0 -0.5 -0.3513 -0.7018 2142705 PK04_097044 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C01 compound treatment 723440.0 123000.0 0.33 548030.0 -574.0 0.0 0.2318 0.7037 2141223 PK04_097045 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C02 compound treatment 719560.0 119000.0 0.32 750680.0 202000.0 0.55 0.6179 0.9655 2141108 PK04_097046 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C03 compound treatment 298970.0 -301000.0 -0.8 452690.0 -95900.0 -0.26 -0.7549 -0.892 2141329 PK04_097047 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C04 compound treatment 382500.0 -218000.0 -0.58 578970.0 30400.0 0.08 -0.352 -0.5995 2141703 PK04_097048 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C05 compound treatment 645840.0 45700.0 0.12 371260.0 -177000.0 -0.49 -0.2579 -0.5137 2065845 PK04_097049 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C06 compound treatment 676870.0 76800.0 0.21 703520.0 155000.0 0.43 0.4457 0.944 2141782 PK04_097050 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C07 compound treatment 613340.0 13200.0 0.04 522920.0 -25700.0 -0.07 -0.0248 -0.315 2141574 PK04_097051 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C08 compound treatment 517150.0 -82900.0 -0.22 536710.0 -11900.0 -0.03 -0.1797 -0.8027 2141856 PK04_097052 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C09 compound treatment 379540.0 -221000.0 -0.59 299520.0 -249000.0 -0.68 -0.9001 -0.9972 2141751 PK04_097053 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C10 compound treatment 385780.0 -214000.0 -0.57 548960.0 356.0 0.0 -0.4041 -0.7059 2141441 PK04_097054 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C11 mock treatment 715280.0 115000.0 0.31 625170.0 76600.0 0.21 0.3662 0.9828 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C12 mock treatment 434350.0 -166000.0 -0.44 611380.0 62800.0 0.17 -0.1912 -0.4024 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C13 compound treatment 279360.0 -321000.0 -0.86 343040.0 -206000.0 -0.56 -1.0048 -0.9795 2141937 PK04_097055 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C14 compound treatment 56250.0 -544000.0 -1.45 127580.0 -421000.0 -1.16 -1.8445 -0.9936 2141727 PK04_097056 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C15 mock treatment 572920.0 -27200.0 -0.07 714950.0 166000.0 0.46 0.2716 0.5873 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C16 mock treatment 716390.0 116000.0 0.31 592190.0 43600.0 0.12 0.3043 0.914 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C17 compound treatment 487910.0 -112000.0 -0.3 683570.0 135000.0 0.37 0.0501 0.1052 2141078 PK04_097057 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C18 compound treatment 349030.0 -251000.0 -0.67 323680.0 -225000.0 -0.62 -0.9108 -0.9992 2141467 PK04_097058 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C19 compound treatment 491950.0 -108000.0 -0.29 573240.0 24600.0 0.07 -0.1564 -0.5273 2141339 PK04_097059 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C20 compound treatment 17700.0 -582000.0 -1.56 21810.0 -527000.0 -1.45 -2.1226 -0.9993 2141364 PK04_097060 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C21 compound treatment 208540.0 -392000.0 -1.05 300010.0 -249000.0 -0.68 -1.2221 -0.9786 2141370 PK04_097061 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C22 compound treatment 686190.0 86100.0 0.23 576430.0 27800.0 0.08 0.2166 0.894 2141489 PK04_097062 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C23 compound treatment 376020.0 -224000.0 -0.6 340270.0 -208000.0 -0.57 -0.8276 -0.9997 2141706 PK04_097063 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 C24 compound treatment 254560.0 -346000.0 -0.92 381020.0 -168000.0 -0.46 -0.9779 -0.9483 2141172 PK04_097064 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D01 compound treatment 332250.0 -268000.0 -0.72 902460.0 354000.0 0.97 0.1811 0.1501 2141788 PK04_097065 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D02 compound treatment 735750.0 136000.0 0.36 666590.0 118000.0 0.32 0.4853 0.9984 2143973 PK04_097066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D03 compound treatment 725480.0 125000.0 0.33 553560.0 4960.0 0.01 0.2464 0.7352 2141854 PK04_097067 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D04 compound treatment 538290.0 -61800.0 -0.17 336230.0 -212000.0 -0.58 -0.529 -0.873 2141969 PK04_097068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D05 compound treatment 781250.0 181000.0 0.48 727100.0 178000.0 0.49 0.6887 1.0 2141087 PK04_097069 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D06 compound treatment 425480.0 -175000.0 -0.47 445250.0 -103000.0 -0.28 -0.5304 -0.9716 2144657 PK04_097070 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D07 compound treatment 648980.0 48900.0 0.13 603420.0 54800.0 0.15 0.1987 0.9975 2141768 PK04_097071 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D08 compound treatment 333960.0 -266000.0 -0.71 343640.0 -205000.0 -0.56 -0.9005 -0.9933 2144733 PK04_097072 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D09 compound treatment 454080.0 -146000.0 -0.39 326140.0 -222000.0 -0.61 -0.7076 -0.9765 2141552 PK04_097073 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D10 compound treatment 276960.0 -323000.0 -0.86 307200.0 -241000.0 -0.66 -1.0789 -0.9915 2143885 PK04_097074 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D11 mock treatment 675080.0 75000.0 0.2 583870.0 35300.0 0.1 0.2101 0.9444 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D12 mock treatment 688360.0 88300.0 0.24 564200.0 15600.0 0.04 0.197 0.8221 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D13 compound treatment 687620.0 87500.0 0.23 477200.0 -71400.0 -0.2 0.0267 0.0875 2141513 PK04_097075 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D14 compound treatment 474190.0 -126000.0 -0.34 260520.0 -288000.0 -0.79 -0.7971 -0.9274 2144449 PK04_097076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D15 mock treatment 754340.0 154000.0 0.41 481220.0 -67400.0 -0.18 0.1605 0.3554 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D16 mock treatment 829650.0 230000.0 0.61 709340.0 161000.0 0.44 0.7456 0.987 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D17 compound treatment 679070.0 79000.0 0.21 336850.0 -212000.0 -0.58 -0.2619 -0.4235 2141816 PK04_097077 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D18 compound treatment 345560.0 -255000.0 -0.68 488550.0 -60100.0 -0.16 -0.5973 -0.8538 2142085 PK04_097078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D19 compound treatment 400900.0 -199000.0 -0.53 636170.0 87600.0 0.24 -0.2062 -0.3532 2141432 PK04_097079 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D20 compound treatment 545080.0 -55000.0 -0.15 561600.0 13000.0 0.04 -0.0787 -0.5203 2144825 PK04_097080 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D21 compound treatment 281240.0 -319000.0 -0.85 306570.0 -242000.0 -0.66 -1.0721 -0.9925 2141123 PK04_097081 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D22 compound treatment 297300.0 -303000.0 -0.81 411480.0 -137000.0 -0.38 -0.8381 -0.9395 2144893 PK04_097082 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D23 compound treatment 485490.0 -115000.0 -0.31 609090.0 60500.0 0.17 -0.099 -0.2844 2141421 PK04_097083 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 D24 compound treatment 555860.0 -44200.0 -0.12 340880.0 -208000.0 -0.57 -0.4868 -0.8359 2143085 PK04_097084 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E01 mock treatment 498130.0 -102000.0 -0.27 315850.0 -233000.0 -0.64 -0.6444 -0.9277 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E02 mock treatment 689890.0 89800.0 0.24 814740.0 266000.0 0.73 0.6862 0.8924 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E03 compound treatment 510110.0 -90000.0 -0.24 452370.0 -96200.0 -0.26 -0.3568 -0.9989 2141878 PK04_097085 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E04 compound treatment 656260.0 56200.0 0.15 655200.0 107000.0 0.29 0.313 0.9518 2141520 PK04_097086 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E05 compound treatment 544880.0 -55200.0 -0.15 339210.0 -209000.0 -0.57 -0.5108 -0.8606 2141359 PK04_097087 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E06 compound treatment 331380.0 -269000.0 -0.72 208800.0 -340000.0 -0.93 -1.1672 -0.9916 2141507 PK04_097088 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E07 compound treatment 532070.0 -68000.0 -0.18 383800.0 -165000.0 -0.45 -0.4484 -0.9197 2141863 PK04_097089 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E08 compound treatment 803130.0 203000.0 0.54 716510.0 168000.0 0.46 0.7094 0.9967 2141163 PK04_097090 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E09 mock treatment 412280.0 -188000.0 -0.5 751090.0 202000.0 0.56 0.0384 0.0512 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E10 mock treatment 766340.0 166000.0 0.44 637890.0 89300.0 0.25 0.4873 0.9608 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E11 compound treatment 334270.0 -266000.0 -0.71 650300.0 102000.0 0.28 -0.3046 -0.3993 2141456 PK04_097091 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E12 compound treatment 177990.0 -422000.0 -1.13 157240.0 -391000.0 -1.07 -1.557 -0.9997 2141683 PK04_097092 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E13 compound treatment 497290.0 -103000.0 -0.27 361490.0 -187000.0 -0.51 -0.5574 -0.9569 2141357 PK04_097093 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E14 compound treatment 71960.0 -528000.0 -1.41 81350.0 -467000.0 -1.28 -1.9046 -0.9989 2141366 PK04_097094 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E15 compound treatment 413700.0 -186000.0 -0.5 533290.0 -15300.0 -0.04 -0.3818 -0.7641 2141575 PK04_097095 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E16 compound treatment 275570.0 -325000.0 -0.87 439850.0 -109000.0 -0.3 -0.824 -0.8988 2141485 PK04_097096 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E17 mock treatment 476440.0 -124000.0 -0.33 682890.0 134000.0 0.37 0.0271 0.0548 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E18 mock treatment 523490.0 -76600.0 -0.2 513070.0 -35500.0 -0.1 -0.2137 -0.9426 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E19 compound treatment 269050.0 -331000.0 -0.88 241950.0 -307000.0 -0.84 -1.2205 -0.9997 2141377 PK04_097097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E20 compound treatment 294100.0 -306000.0 -0.82 193920.0 -355000.0 -0.97 -1.2665 -0.9962 2141326 PK04_097098 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E21 compound treatment 269040.0 -331000.0 -0.88 238350.0 -310000.0 -0.85 -1.2276 -0.9998 2141702 PK04_097099 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E22 compound treatment 547230.0 -52900.0 -0.14 538450.0 -10200.0 -0.03 -0.1196 -0.8307 2141417 PK04_097100 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E23 compound treatment 620200.0 20100.0 0.05 435280.0 -113000.0 -0.31 -0.182 -0.5765 2141167 PK04_097101 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 E24 compound treatment 374940.0 -225000.0 -0.6 321180.0 -227000.0 -0.62 -0.8667 -0.9998 2141113 PK04_097102 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F01 mock treatment 666080.0 66000.0 0.18 845660.0 297000.0 0.82 0.7013 0.8405 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F02 mock treatment 523200.0 -76900.0 -0.21 481240.0 -67400.0 -0.18 -0.276 -0.9986 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F03 compound treatment 420000.0 -180000.0 -0.48 789640.0 241000.0 0.66 0.1278 0.1562 2141216 PK04_097103 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F04 compound treatment 453760.0 -146000.0 -0.39 364870.0 -184000.0 -0.5 -0.6331 -0.9921 2142933 PK04_097104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F05 compound treatment 285120.0 -315000.0 -0.84 477050.0 -71600.0 -0.2 -0.7338 -0.8494 2141355 PK04_097105 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F06 compound treatment 640210.0 40100.0 0.11 529820.0 -18800.0 -0.05 0.0393 0.3305 2142833 PK04_097106 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F07 compound treatment 369680.0 -230000.0 -0.62 452980.0 -95600.0 -0.26 -0.6208 -0.9278 2141414 PK04_097107 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F08 compound treatment 784170.0 184000.0 0.49 623940.0 75300.0 0.21 0.4939 0.926 2144249 PK04_097108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F09 mock treatment 737130.0 137000.0 0.37 708020.0 159000.0 0.44 0.5683 0.996 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F10 mock treatment 686630.0 86500.0 0.23 583900.0 35300.0 0.1 0.232 0.9255 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F11 compound treatment 375440.0 -225000.0 -0.6 302920.0 -246000.0 -0.67 -0.9012 -0.9983 2141568 PK04_097109 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F12 compound treatment 347730.0 -252000.0 -0.67 205530.0 -343000.0 -0.94 -1.1426 -0.9865 2142765 PK04_097110 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F13 compound treatment 708170.0 108000.0 0.29 319590.0 -229000.0 -0.63 -0.2405 -0.3476 2141348 PK04_097111 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F14 compound treatment 522260.0 -77800.0 -0.21 227690.0 -321000.0 -0.88 -0.77 -0.8506 2142645 PK04_097112 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F15 compound treatment 331620.0 -268000.0 -0.72 495530.0 -53100.0 -0.15 -0.6101 -0.8337 2141505 PK04_097113 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F16 compound treatment 408870.0 -191000.0 -0.51 388960.0 -160000.0 -0.44 -0.6711 -0.9971 2142977 PK04_097114 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F17 mock treatment 454350.0 -146000.0 -0.39 326160.0 -222000.0 -0.61 -0.7071 -0.9764 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F18 mock treatment 359860.0 -240000.0 -0.64 570450.0 21800.0 0.06 -0.4113 -0.6382 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F19 compound treatment 400010.0 -200000.0 -0.53 333760.0 -215000.0 -0.59 -0.795 -0.9988 2141200 PK04_097115 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F20 compound treatment 297410.0 -303000.0 -0.81 281920.0 -267000.0 -0.73 -1.0894 -0.9988 2142045 PK04_097116 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F21 compound treatment 213440.0 -387000.0 -1.03 388400.0 -160000.0 -0.44 -1.0413 -0.9276 2141938 PK04_097117 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F22 compound treatment 435230.0 -165000.0 -0.44 558810.0 10200.0 0.03 -0.2916 -0.6608 2144373 PK04_097118 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F23 compound treatment 392640.0 -207000.0 -0.55 261560.0 -287000.0 -0.79 -0.9491 -0.9851 2141419 PK04_097119 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 F24 compound treatment 212850.0 -387000.0 -1.03 308160.0 -240000.0 -0.66 -1.1982 -0.9765 2142769 PK04_097120 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G01 compound treatment 495040.0 -105000.0 -0.28 516040.0 -32600.0 -0.09 -0.2616 -0.8884 2141178 PK04_097121 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G02 compound treatment 677860.0 77800.0 0.21 694400.0 146000.0 0.4 0.4299 0.9533 2141487 PK04_097122 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G03 mock treatment 785050.0 185000.0 0.49 650930.0 102000.0 0.28 0.548 0.9642 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G04 mock treatment 411200.0 -189000.0 -0.5 357760.0 -191000.0 -0.52 -0.7272 -0.9998 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G05 compound treatment 570110.0 -30000.0 -0.08 728970.0 180000.0 0.5 0.2935 0.5851 2141519 PK04_097123 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G06 compound treatment 645980.0 45900.0 0.12 447220.0 -101000.0 -0.28 -0.1102 -0.3622 2141537 PK04_097124 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G07 compound treatment 387960.0 -212000.0 -0.57 494400.0 -54200.0 -0.15 -0.5059 -0.8635 2141722 PK04_097125 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G08 compound treatment 566400.0 -33700.0 -0.09 405380.0 -143000.0 -0.39 -0.3417 -0.8471 2141577 PK04_097126 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G09 compound treatment 612480.0 12400.0 0.03 445930.0 -103000.0 -0.28 -0.1759 -0.6199 2141458 PK04_097127 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G10 compound treatment 753600.0 154000.0 0.41 427870.0 -121000.0 -0.33 0.0555 0.1053 2141190 PK04_097128 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G11 compound treatment 407360.0 -193000.0 -0.51 393320.0 -155000.0 -0.43 -0.6655 -0.9956 2141333 PK04_097129 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G12 compound treatment 428250.0 -172000.0 -0.46 264230.0 -284000.0 -0.78 -0.8766 -0.9679 2141508 PK04_097130 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G13 compound treatment 836520.0 236000.0 0.63 287560.0 -261000.0 -0.72 -0.0602 -0.0631 2141118 PK04_097131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G14 compound treatment 327400.0 -273000.0 -0.73 303730.0 -245000.0 -0.67 -0.9904 -0.9992 2141927 PK04_097132 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G15 compound treatment 438300.0 -162000.0 -0.43 392040.0 -157000.0 -0.43 -0.6095 -1.0 2141159 PK04_097133 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G16 compound treatment 447640.0 -152000.0 -0.41 550200.0 1600.0 0.0 -0.2848 -0.6995 2141713 PK04_097134 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G17 compound treatment 392850.0 -207000.0 -0.55 389830.0 -159000.0 -0.44 -0.6996 -0.993 2141795 PK04_097135 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G18 compound treatment 556800.0 -43300.0 -0.12 472050.0 -76600.0 -0.21 -0.2304 -0.9604 2141553 PK04_097136 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G19 mock treatment 555220.0 -44900.0 -0.12 514190.0 -34400.0 -0.09 -0.1516 -0.9931 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G20 mock treatment 746370.0 146000.0 0.39 401470.0 -147000.0 -0.4 -0.0094 -0.0167 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G21 compound treatment 579840.0 -20300.0 -0.05 322720.0 -226000.0 -0.62 -0.4768 -0.7659 2141819 PK04_097137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G22 compound treatment 439400.0 -161000.0 -0.43 309030.0 -240000.0 -0.66 -0.7686 -0.9786 2141516 PK04_097138 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G23 compound treatment 684970.0 84900.0 0.23 373180.0 -175000.0 -0.48 -0.1803 -0.3386 2141691 PK04_097139 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 G24 compound treatment 331010.0 -269000.0 -0.72 323650.0 -225000.0 -0.62 -0.9449 -0.9971 2141155 PK04_097140 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H01 compound treatment 488200.0 -112000.0 -0.3 804750.0 256000.0 0.7 0.2859 0.3742 2141157 PK04_097141 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H02 compound treatment 566850.0 -33200.0 -0.09 268830.0 -280000.0 -0.77 -0.6059 -0.7836 2143037 PK04_097142 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H03 mock treatment 533800.0 -66300.0 -0.18 614560.0 66000.0 0.18 0.0028 0.0112 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H04 mock treatment 891960.0 292000.0 0.78 754160.0 206000.0 0.56 0.9503 0.9874 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H05 compound treatment 318940.0 -281000.0 -0.75 440050.0 -109000.0 -0.3 -0.7417 -0.9181 2141926 PK04_097143 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H06 compound treatment 392260.0 -208000.0 -0.56 419100.0 -130000.0 -0.36 -0.6439 -0.9768 2143177 PK04_097144 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H07 compound treatment 755070.0 155000.0 0.41 805440.0 257000.0 0.71 0.7913 0.9678 2141694 PK04_097145 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H08 compound treatment 490340.0 -110000.0 -0.29 756220.0 208000.0 0.57 0.1958 0.3054 2143025 PK04_097146 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H09 compound treatment 275800.0 -324000.0 -0.87 312380.0 -236000.0 -0.65 -1.0711 -0.9898 2141749 PK04_097147 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H10 compound treatment 593120.0 -6980.0 -0.02 694640.0 146000.0 0.4 0.2703 0.6735 2143077 PK04_097148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H11 compound treatment 252320.0 -348000.0 -0.93 700530.0 152000.0 0.42 -0.3619 -0.3554 2141097 PK04_097149 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H12 compound treatment 361920.0 -238000.0 -0.64 518990.0 -29600.0 -0.08 -0.5073 -0.791 2142913 PK04_097150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H13 compound treatment 313000.0 -287000.0 -0.77 216350.0 -332000.0 -0.91 -1.1872 -0.9963 2141401 PK04_097151 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H14 compound treatment 172720.0 -427000.0 -1.14 391560.0 -157000.0 -0.43 -1.112 -0.9113 2143093 PK04_097152 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H15 compound treatment 467720.0 -132000.0 -0.35 344330.0 -204000.0 -0.56 -0.6466 -0.9753 2141777 PK04_097153 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H16 compound treatment 698570.0 98500.0 0.26 305340.0 -243000.0 -0.67 -0.2863 -0.3988 2143865 PK04_097154 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H17 compound treatment 548560.0 -51500.0 -0.14 478570.0 -70000.0 -0.19 -0.2333 -0.9866 2141142 PK04_097155 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H18 compound treatment 451780.0 -148000.0 -0.4 367520.0 -181000.0 -0.5 -0.6317 -0.9937 2143925 PK04_097156 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H19 mock treatment 239010.0 -361000.0 -0.96 317210.0 -231000.0 -0.64 -1.1312 -0.9795 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H20 mock treatment 384340.0 -216000.0 -0.58 368740.0 -180000.0 -0.49 -0.7567 -0.997 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H21 compound treatment 584060.0 -16000.0 -0.04 437990.0 -111000.0 -0.3 -0.245 -0.7989 2141168 PK04_097157 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H22 compound treatment 584870.0 -15200.0 -0.04 266210.0 -282000.0 -0.78 -0.577 -0.7432 2143057 PK04_097158 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H23 compound treatment 578620.0 -21500.0 -0.06 742420.0 194000.0 0.53 0.3357 0.6272 2141804 PK04_097159 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 H24 compound treatment 425990.0 -174000.0 -0.47 697500.0 149000.0 0.41 -0.0398 -0.0642 2142649 PK04_097160 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I01 compound treatment 602430.0 2330.0 0.01 406400.0 -142000.0 -0.39 -0.2717 -0.6957 2141890 PK04_097161 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I02 compound treatment 381320.0 -219000.0 -0.58 823100.0 274000.0 0.75 0.1197 0.1255 2141465 PK04_097162 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I03 compound treatment 410720.0 -189000.0 -0.51 351330.0 -197000.0 -0.54 -0.7406 -0.9994 2141772 PK04_097163 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I04 compound treatment 709830.0 110000.0 0.29 377030.0 -172000.0 -0.47 -0.1258 -0.2268 2141343 PK04_097164 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I05 mock treatment 442640.0 -157000.0 -0.42 370320.0 -178000.0 -0.49 -0.6435 -0.9971 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I06 mock treatment 454670.0 -145000.0 -0.39 545760.0 -2840.0 -0.01 -0.2802 -0.7212 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I07 compound treatment 504230.0 -95900.0 -0.26 538750.0 -9850.0 -0.03 -0.2002 -0.7775 2141794 PK04_097165 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I08 compound treatment 348990.0 -251000.0 -0.67 637700.0 89100.0 0.24 -0.3013 -0.422 2141922 PK04_097166 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I09 compound treatment 729730.0 130000.0 0.35 611230.0 62600.0 0.17 0.3664 0.9478 2141780 PK04_097167 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I10 compound treatment 614920.0 14800.0 0.04 522530.0 -26100.0 -0.07 -0.0226 -0.2765 2141799 PK04_097168 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I11 compound treatment 367910.0 -232000.0 -0.62 476010.0 -72600.0 -0.2 -0.5795 -0.8895 2141177 PK04_097169 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I12 compound treatment 368870.0 -231000.0 -0.62 455900.0 -92700.0 -0.25 -0.6167 -0.9232 2141747 PK04_097170 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I13 compound treatment 365440.0 -235000.0 -0.63 679720.0 131000.0 0.36 -0.1887 -0.261 2141423 PK04_097171 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I14 compound treatment 475280.0 -125000.0 -0.33 510830.0 -37800.0 -0.1 -0.3091 -0.8852 2141775 PK04_097172 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I15 compound treatment 433010.0 -167000.0 -0.45 350140.0 -198000.0 -0.54 -0.7009 -0.9951 2141538 PK04_097173 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I16 compound treatment 472770.0 -127000.0 -0.34 346790.0 -202000.0 -0.55 -0.6323 -0.9725 2065871 PK04_097174 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I17 compound treatment 328480.0 -272000.0 -0.73 379680.0 -169000.0 -0.46 -0.8409 -0.9766 2141729 PK04_097175 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I18 compound treatment 389760.0 -210000.0 -0.56 403840.0 -145000.0 -0.4 -0.6783 -0.9856 2141892 PK04_097176 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I19 compound treatment 539800.0 -60300.0 -0.16 309450.0 -239000.0 -0.66 -0.5782 -0.8552 2141687 PK04_097177 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I20 compound treatment 598660.0 -1440.0 0.0 268710.0 -280000.0 -0.77 -0.5461 -0.7106 2141680 PK04_097178 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I21 mock treatment 414370.0 -186000.0 -0.5 356640.0 -192000.0 -0.53 -0.7234 -0.9995 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I22 mock treatment 403260.0 -197000.0 -0.53 564160.0 15600.0 0.04 -0.3416 -0.6475 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I23 compound treatment 582960.0 -17100.0 -0.05 661690.0 113000.0 0.31 0.1872 0.5964 2141841 PK04_097179 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 I24 compound treatment 436660.0 -163000.0 -0.44 395950.0 -153000.0 -0.42 -0.605 -0.9998 2141766 PK04_097180 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J01 compound treatment 608960.0 8860.0 0.02 739210.0 191000.0 0.52 0.3868 0.7383 2141705 PK04_097181 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J02 compound treatment 504350.0 -95700.0 -0.26 451810.0 -96800.0 -0.27 -0.3687 -0.9998 2143397 PK04_097182 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J03 compound treatment 764880.0 165000.0 0.44 547780.0 -824.0 0.0 0.3096 0.7035 2141179 PK04_097183 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J04 compound treatment 455730.0 -144000.0 -0.39 440690.0 -108000.0 -0.3 -0.4822 -0.9915 2144337 PK04_097184 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J05 mock treatment 390690.0 -209000.0 -0.56 713820.0 165000.0 0.45 -0.0748 -0.1038 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J06 mock treatment 342800.0 -257000.0 -0.69 523120.0 -25500.0 -0.07 -0.5354 -0.7751 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J07 compound treatment 762840.0 163000.0 0.43 705150.0 157000.0 0.43 0.6113 1.0 2141805 PK04_097185 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J08 compound treatment 355170.0 -245000.0 -0.65 455860.0 -92700.0 -0.25 -0.6426 -0.9154 2143365 PK04_097186 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J09 compound treatment 295790.0 -304000.0 -0.81 340600.0 -208000.0 -0.57 -0.9785 -0.9851 2141901 PK04_097187 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J10 compound treatment 397600.0 -202000.0 -0.54 405280.0 -143000.0 -0.39 -0.6607 -0.9878 2144881 PK04_097188 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J11 compound treatment 354880.0 -245000.0 -0.65 535600.0 -13000.0 -0.04 -0.4884 -0.7445 2141717 PK04_097189 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J12 compound treatment 288430.0 -312000.0 -0.83 306900.0 -242000.0 -0.66 -1.0579 -0.9937 2143405 PK04_097190 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J13 compound treatment 548970.0 -51100.0 -0.14 321450.0 -227000.0 -0.62 -0.5375 -0.842 2141188 PK04_097191 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J14 compound treatment 358830.0 -241000.0 -0.64 418940.0 -130000.0 -0.36 -0.7074 -0.9609 2142929 PK04_097192 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J15 compound treatment 456820.0 -143000.0 -0.38 346240.0 -202000.0 -0.56 -0.6635 -0.9834 2141365 PK04_097193 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J16 compound treatment 611040.0 10900.0 0.03 638790.0 90200.0 0.25 0.1957 0.7851 2144325 PK04_097194 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J17 compound treatment 229700.0 -370000.0 -0.99 301890.0 -247000.0 -0.68 -1.1785 -0.9829 2141221 PK04_097195 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J18 compound treatment 486780.0 -113000.0 -0.3 373820.0 -175000.0 -0.48 -0.5533 -0.9753 2143377 PK04_097196 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J19 compound treatment 449010.0 -151000.0 -0.4 267410.0 -281000.0 -0.77 -0.8312 -0.9542 2141815 PK04_097197 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J20 compound treatment 356680.0 -243000.0 -0.65 399380.0 -149000.0 -0.41 -0.7494 -0.9752 2142585 PK04_097198 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J21 mock treatment 628490.0 28400.0 0.08 349670.0 -199000.0 -0.55 -0.3326 -0.6031 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J22 mock treatment 363760.0 -236000.0 -0.63 441120.0 -107000.0 -0.3 -0.655 -0.94 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J23 compound treatment 558980.0 -41100.0 -0.11 378050.0 -171000.0 -0.47 -0.4088 -0.8499 2141186 PK04_097199 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 J24 compound treatment 237790.0 -362000.0 -0.97 377450.0 -171000.0 -0.47 -1.0165 -0.9449 2144237 PK04_097200 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K01 compound treatment 462850.0 -137000.0 -0.37 455080.0 -93500.0 -0.26 -0.4408 -0.9848 2141164 PK04_097201 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K02 compound treatment 888280.0 288000.0 0.77 862760.0 314000.0 0.86 1.1542 0.9984 2141443 PK04_097202 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K03 compound treatment 511780.0 -88300.0 -0.24 386200.0 -162000.0 -0.45 -0.4821 -0.9557 2141548 PK04_097203 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K04 compound treatment 437440.0 -163000.0 -0.43 561180.0 12600.0 0.03 -0.2828 -0.6489 2141351 PK04_097204 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K05 compound treatment 391650.0 -208000.0 -0.56 449310.0 -99300.0 -0.27 -0.5864 -0.946 2141786 PK04_097205 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K06 compound treatment 602330.0 2230.0 0.01 555210.0 6610.0 0.02 0.017 0.8927 2141746 PK04_097206 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K07 mock treatment 753980.0 154000.0 0.41 391900.0 -157000.0 -0.43 -0.0136 -0.0228 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K08 mock treatment 652260.0 52200.0 0.14 558810.0 10200.0 0.03 0.1183 0.8326 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K09 compound treatment 316050.0 -284000.0 -0.76 272480.0 -276000.0 -0.76 -1.0725 -1.0 2141350 PK04_097207 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K10 compound treatment 370740.0 -229000.0 -0.61 374350.0 -174000.0 -0.48 -0.7715 -0.9925 2141331 PK04_097208 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K11 compound treatment 534670.0 -65400.0 -0.17 597150.0 48500.0 0.13 -0.0293 -0.1334 2141806 PK04_097209 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K12 compound treatment 613920.0 13800.0 0.04 412750.0 -136000.0 -0.37 -0.2376 -0.634 2141720 PK04_097210 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K13 compound treatment 424500.0 -176000.0 -0.47 264720.0 -284000.0 -0.78 -0.8827 -0.9705 2141904 PK04_097211 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K14 compound treatment 576320.0 -23800.0 -0.06 278250.0 -270000.0 -0.74 -0.5697 -0.7648 2141222 PK04_097212 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K15 mock treatment 554080.0 -46000.0 -0.12 559360.0 10800.0 0.03 -0.066 -0.5224 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K16 mock treatment 639240.0 39100.0 0.1 480800.0 -67800.0 -0.19 -0.0577 -0.2702 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K17 compound treatment 402660.0 -197000.0 -0.53 696820.0 148000.0 0.41 -0.0852 -0.1278 2141773 PK04_097213 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K18 compound treatment 805440.0 205000.0 0.55 436910.0 -112000.0 -0.31 0.171 0.2721 2141524 PK04_097214 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K19 compound treatment 615430.0 15300.0 0.04 572390.0 23800.0 0.07 0.0751 0.9747 2141218 PK04_097215 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K20 compound treatment 401780.0 -198000.0 -0.53 349610.0 -199000.0 -0.55 -0.7609 -0.9999 2141861 PK04_097216 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K21 compound treatment 454920.0 -145000.0 -0.39 402420.0 -146000.0 -0.4 -0.558 -0.9999 2141117 PK04_097217 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K22 compound treatment 374170.0 -226000.0 -0.6 403580.0 -145000.0 -0.4 -0.7082 -0.9796 2141354 PK04_097218 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K23 mock treatment 772490.0 172000.0 0.46 602190.0 53600.0 0.15 0.4296 0.8888 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 K24 mock treatment 535780.0 -64300.0 -0.17 237390.0 -311000.0 -0.85 -0.7256 -0.8326 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L01 compound treatment 248710.0 -351000.0 -0.94 419710.0 -129000.0 -0.35 -0.9139 -0.9111 2141684 PK04_097219 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L02 compound treatment 611050.0 11000.0 0.03 725720.0 177000.0 0.49 0.3645 0.7483 2143489 PK04_097220 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L03 compound treatment 373200.0 -227000.0 -0.61 382560.0 -166000.0 -0.46 -0.7509 -0.9901 2141375 PK04_097221 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L04 compound treatment 467520.0 -133000.0 -0.35 605600.0 57000.0 0.16 -0.1397 -0.361 2143313 PK04_097222 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L05 compound treatment 290410.0 -310000.0 -0.83 427640.0 -121000.0 -0.33 -0.8197 -0.9196 2141889 PK04_097223 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L06 compound treatment 395450.0 -205000.0 -0.55 447920.0 -101000.0 -0.28 -0.582 -0.9501 2144793 PK04_097224 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L07 mock treatment 567040.0 -33100.0 -0.09 552440.0 3840.0 0.01 -0.055 -0.6184 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L08 mock treatment 783390.0 183000.0 0.49 546910.0 -1690.0 0.0 0.3429 0.7004 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L09 compound treatment 787900.0 188000.0 0.5 808590.0 260000.0 0.71 0.8594 0.9851 2141438 PK04_097225 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L10 compound treatment 684900.0 84800.0 0.23 732210.0 184000.0 0.5 0.5166 0.9348 2142993 PK04_097226 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L11 compound treatment 662800.0 62700.0 0.17 627930.0 79300.0 0.22 0.2724 0.9916 2141185 PK04_097227 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L12 compound treatment 453770.0 -146000.0 -0.39 607270.0 58700.0 0.16 -0.1625 -0.3844 2144653 PK04_097228 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L13 compound treatment 675140.0 75000.0 0.2 674330.0 126000.0 0.35 0.3858 0.9666 2141893 PK04_097229 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L14 compound treatment 738280.0 138000.0 0.37 472350.0 -76300.0 -0.21 0.113 0.2662 2143417 PK04_097230 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L15 mock treatment 579240.0 -20900.0 -0.06 538080.0 -10500.0 -0.03 -0.0598 -0.9533 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L16 mock treatment 562190.0 -37900.0 -0.1 638080.0 89500.0 0.25 0.1021 0.3843 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L17 compound treatment 634720.0 34600.0 0.09 443430.0 -105000.0 -0.29 -0.1388 -0.4577 2141152 PK04_097231 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L18 compound treatment 807090.0 207000.0 0.55 505090.0 -43500.0 -0.12 0.3065 0.5418 2143325 PK04_097232 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L19 compound treatment 551550.0 -48500.0 -0.13 336040.0 -213000.0 -0.58 -0.5043 -0.8436 2141709 PK04_097233 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L20 compound treatment 484810.0 -115000.0 -0.31 378030.0 -171000.0 -0.47 -0.5489 -0.9793 2142773 PK04_097234 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L21 compound treatment 758630.0 159000.0 0.42 626990.0 78400.0 0.22 0.4516 0.9507 2141174 PK04_097235 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L22 compound treatment 601040.0 944.0 0.0 699720.0 151000.0 0.41 0.2951 0.7114 2142985 PK04_097236 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L23 mock treatment 770340.0 170000.0 0.45 473990.0 -74600.0 -0.2 0.1767 0.3543 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 L24 mock treatment 828660.0 229000.0 0.61 787970.0 239000.0 0.66 0.8964 0.9993 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M01 compound treatment 623360.0 23300.0 0.06 542330.0 -6270.0 -0.02 0.0318 0.4925 2141838 PK04_097237 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M02 compound treatment 812250.0 212000.0 0.57 621000.0 72400.0 0.2 0.5412 0.9013 2141189 PK04_097238 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M03 compound treatment 456740.0 -143000.0 -0.38 569450.0 20800.0 0.06 -0.2303 -0.5948 2141724 PK04_097239 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M04 compound treatment 417040.0 -183000.0 -0.49 601860.0 53300.0 0.15 -0.2423 -0.4749 2141153 PK04_097240 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M05 compound treatment 676730.0 76600.0 0.2 749470.0 201000.0 0.55 0.5347 0.909 2141436 PK04_097241 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M06 compound treatment 592280.0 -7820.0 -0.02 624090.0 75500.0 0.21 0.1318 0.6327 2141769 PK04_097242 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M07 compound treatment 513610.0 -86500.0 -0.23 654650.0 106000.0 0.29 0.0425 0.1144 2141771 PK04_097243 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M08 compound treatment 474160.0 -126000.0 -0.34 582400.0 33800.0 0.09 -0.1722 -0.4936 2141480 PK04_097244 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M09 mock treatment 812600.0 213000.0 0.57 755280.0 207000.0 0.57 0.8026 1.0 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M10 mock treatment 667330.0 67200.0 0.18 596420.0 47800.0 0.13 0.2198 0.9881 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M11 compound treatment 560610.0 -39500.0 -0.11 507390.0 -41200.0 -0.11 -0.1546 -0.9994 2141571 PK04_097245 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M12 compound treatment 310140.0 -290000.0 -0.77 290240.0 -258000.0 -0.71 -1.0492 -0.999 2141879 PK04_097246 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M13 mock treatment 676830.0 76700.0 0.2 481210.0 -67400.0 -0.19 0.0141 0.051 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M14 mock treatment 488520.0 -112000.0 -0.3 763730.0 215000.0 0.59 0.2069 0.3127 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M15 compound treatment 739870.0 140000.0 0.37 408510.0 -140000.0 -0.38 -0.008 -0.0149 2141832 PK04_097247 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M16 compound treatment 521800.0 -78300.0 -0.21 481730.0 -66900.0 -0.18 -0.2777 -0.9979 2141542 PK04_097248 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M17 compound treatment 510660.0 -89400.0 -0.24 270560.0 -278000.0 -0.76 -0.7087 -0.886 2141399 PK04_097249 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M18 compound treatment 486580.0 -114000.0 -0.3 334310.0 -214000.0 -0.59 -0.6304 -0.9525 2141903 PK04_097250 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M19 compound treatment 32270.0 -568000.0 -1.52 65020.0 -484000.0 -1.33 -2.0112 -0.9978 2141716 PK04_097251 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M20 compound treatment 493870.0 -106000.0 -0.28 367710.0 -181000.0 -0.5 -0.5518 -0.9647 2141203 PK04_097252 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M21 compound treatment 506240.0 -93900.0 -0.25 482320.0 -66300.0 -0.18 -0.3059 -0.9876 2141110 PK04_097253 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M22 compound treatment 372610.0 -227000.0 -0.61 577350.0 28700.0 0.08 -0.3738 -0.6101 2141731 PK04_097254 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M23 compound treatment 476230.0 -124000.0 -0.33 518080.0 -30500.0 -0.08 -0.2932 -0.8591 2141095 PK04_097255 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 M24 compound treatment 606420.0 6320.0 0.02 463610.0 -85000.0 -0.23 -0.1531 -0.6542 2141894 PK04_097256 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N01 compound treatment 539390.0 -60700.0 -0.16 744770.0 196000.0 0.54 0.2662 0.4732 2141340 PK04_097257 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N02 compound treatment 512420.0 -87700.0 -0.23 684500.0 136000.0 0.37 0.0982 0.223 2142089 PK04_097258 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N03 compound treatment 764640.0 165000.0 0.44 799140.0 251000.0 0.69 0.7971 0.9766 2141511 PK04_097259 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N04 compound treatment 444890.0 -155000.0 -0.41 338530.0 -210000.0 -0.58 -0.701 -0.9869 2144305 PK04_097260 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N05 compound treatment 493230.0 -107000.0 -0.29 684490.0 136000.0 0.37 0.062 0.1319 2141839 PK04_097261 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N06 compound treatment 820750.0 221000.0 0.59 752030.0 203000.0 0.56 0.8117 0.9996 2142057 PK04_097262 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N07 compound treatment 832000.0 232000.0 0.62 476650.0 -72000.0 -0.2 0.2983 0.4588 2141431 PK04_097263 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N08 compound treatment 777440.0 177000.0 0.47 662080.0 113000.0 0.31 0.5552 0.9793 2144369 PK04_097264 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N09 mock treatment 861050.0 261000.0 0.7 583110.0 34500.0 0.09 0.5598 0.7959 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N10 mock treatment 728800.0 129000.0 0.34 576730.0 28100.0 0.08 0.2977 0.8449 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N11 compound treatment 803040.0 203000.0 0.54 333970.0 -215000.0 -0.59 -0.0334 -0.0417 2141527 PK04_097265 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N12 compound treatment 661050.0 61000.0 0.16 616650.0 68000.0 0.19 0.2472 0.9977 2144009 PK04_097266 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N13 mock treatment 789160.0 189000.0 0.5 595000.0 46400.0 0.13 0.4471 0.8586 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N14 mock treatment 818560.0 218000.0 0.58 574190.0 25600.0 0.07 0.4623 0.7866 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N15 compound treatment 576090.0 -24000.0 -0.06 647150.0 98500.0 0.27 0.146 0.525 2141907 PK04_097267 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N16 compound treatment 687860.0 87800.0 0.23 317460.0 -231000.0 -0.63 -0.283 -0.4183 2143157 PK04_097268 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N17 compound treatment 800840.0 201000.0 0.54 353560.0 -195000.0 -0.54 5.0E-4 7.0E-4 2141544 PK04_097269 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N18 compound treatment 653780.0 53700.0 0.14 388970.0 -160000.0 -0.44 -0.2085 -0.4522 2144297 PK04_097270 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N19 compound treatment 550300.0 -49800.0 -0.13 418120.0 -130000.0 -0.36 -0.3474 -0.909 2141483 PK04_097271 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N20 compound treatment 555960.0 -44100.0 -0.12 591970.0 43400.0 0.12 8.0E-4 0.0049 2142217 PK04_097272 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N21 compound treatment 656000.0 55900.0 0.15 644080.0 95500.0 0.26 0.2909 0.9644 2141887 PK04_097273 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N22 compound treatment 567520.0 -32600.0 -0.09 612700.0 64100.0 0.18 0.0629 0.3204 2143065 PK04_097274 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N23 compound treatment 652320.0 52200.0 0.14 669670.0 121000.0 0.33 0.3337 0.9256 2141817 PK04_097275 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 N24 compound treatment 590140.0 -9960.0 -0.03 483060.0 -65500.0 -0.18 -0.146 -0.8029 2144333 PK04_097276 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O01 compound treatment 615560.0 15500.0 0.04 596840.0 48200.0 0.13 0.1228 0.8856 2141166 PK04_097277 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O02 compound treatment 367550.0 -233000.0 -0.62 564000.0 15400.0 0.04 -0.4093 -0.6575 2141900 PK04_097278 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O03 compound treatment 548750.0 -51300.0 -0.14 680810.0 132000.0 0.36 0.1597 0.4115 2141790 PK04_097279 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O04 compound treatment 437840.0 -162000.0 -0.43 414110.0 -134000.0 -0.37 -0.5675 -0.9968 2141883 PK04_097280 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O05 compound treatment 619200.0 19100.0 0.05 615450.0 66800.0 0.18 0.1658 0.8707 2141427 PK04_097281 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O06 compound treatment 464700.0 -135000.0 -0.36 431140.0 -117000.0 -0.32 -0.4838 -0.9984 2141093 PK04_097282 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O07 compound treatment 491640.0 -108000.0 -0.29 669890.0 121000.0 0.33 0.0306 0.0694 2141812 PK04_097283 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O08 compound treatment 798770.0 199000.0 0.53 768090.0 219000.0 0.6 0.8013 0.998 2141430 PK04_097284 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O09 compound treatment 677030.0 76900.0 0.21 506820.0 -41800.0 -0.11 0.0642 0.2727 2141454 PK04_097285 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O10 compound treatment 638880.0 38800.0 0.1 447440.0 -101000.0 -0.28 -0.1231 -0.4154 2141529 PK04_097286 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O11 mock treatment 679910.0 79800.0 0.21 445600.0 -103000.0 -0.28 -0.0492 -0.139 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O12 mock treatment 553080.0 -47000.0 -0.13 416550.0 -132000.0 -0.36 -0.3452 -0.8996 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O13 compound treatment 556560.0 -43500.0 -0.12 390410.0 -158000.0 -0.43 -0.3893 -0.8659 2141368 PK04_097287 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O14 compound treatment 354530.0 -246000.0 -0.66 460500.0 -88100.0 -0.24 -0.6348 -0.9081 2141362 PK04_097288 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O15 compound treatment 585980.0 -14100.0 -0.04 505570.0 -43000.0 -0.12 -0.1102 -0.8886 2141460 PK04_097289 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O16 compound treatment 491460.0 -109000.0 -0.29 312250.0 -236000.0 -0.65 -0.664 -0.9342 2141860 PK04_097290 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O17 compound treatment 466400.0 -134000.0 -0.36 448900.0 -99700.0 -0.27 -0.4461 -0.9914 2141175 PK04_097291 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O18 compound treatment 634400.0 34300.0 0.09 296480.0 -252000.0 -0.69 -0.4247 -0.6082 2141486 PK04_097292 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O19 compound treatment 334030.0 -266000.0 -0.71 291600.0 -257000.0 -0.71 -1.0014 -1.0 2141156 PK04_097293 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O20 compound treatment 494370.0 -106000.0 -0.28 377190.0 -171000.0 -0.47 -0.5324 -0.9702 2141685 PK04_097294 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O21 compound treatment 407170.0 -193000.0 -0.52 345300.0 -203000.0 -0.56 -0.759 -0.9992 2141094 PK04_097295 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O22 compound treatment 275040.0 -325000.0 -0.87 324160.0 -224000.0 -0.62 -1.0496 -0.9859 2141379 PK04_097296 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O23 compound treatment 128420.0 -472000.0 -1.26 328000.0 -221000.0 -0.61 -1.3191 -0.9437 2141397 PK04_097297 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 O24 compound treatment 409700.0 -190000.0 -0.51 384800.0 -164000.0 -0.45 -0.6776 -0.9981 2065842 PK04_097298 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P01 compound treatment 219590.0 -381000.0 -1.02 209960.0 -339000.0 -0.93 -1.3761 -0.999 2141898 PK04_097299 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P02 compound treatment 420640.0 -179000.0 -0.48 351800.0 -197000.0 -0.54 -0.721 -0.9982 2143305 PK04_097300 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P03 compound treatment 418880.0 -181000.0 -0.48 502490.0 -46100.0 -0.13 -0.4318 -0.863 2141555 PK04_097301 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P04 compound treatment 389280.0 -211000.0 -0.56 474200.0 -74400.0 -0.2 -0.5426 -0.9059 2144945 PK04_097302 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P05 compound treatment 145730.0 -454000.0 -1.21 272020.0 -277000.0 -0.76 -1.3951 -0.9745 2141923 PK04_097303 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P06 compound treatment 447950.0 -152000.0 -0.41 476380.0 -72200.0 -0.2 -0.4276 -0.9456 2144433 PK04_097304 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P07 compound treatment 517030.0 -83100.0 -0.22 366160.0 -182000.0 -0.5 -0.5111 -0.9329 2141482 PK04_097305 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P08 compound treatment 475890.0 -124000.0 -0.33 532080.0 -16500.0 -0.05 -0.2667 -0.7964 2143929 PK04_097306 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P09 compound treatment 436500.0 -164000.0 -0.44 433370.0 -115000.0 -0.32 -0.5327 -0.9874 2141698 PK04_097307 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P10 compound treatment 480850.0 -119000.0 -0.32 421240.0 -127000.0 -0.35 -0.4725 -0.9989 2142653 PK04_097308 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P11 mock treatment 413460.0 -187000.0 -0.5 368590.0 -180000.0 -0.49 -0.702 -1.0 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P12 mock treatment 398720.0 -201000.0 -0.54 230590.0 -318000.0 -0.87 -0.9977 -0.9729 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P13 compound treatment 397690.0 -202000.0 -0.54 276070.0 -273000.0 -0.75 -0.9114 -0.9873 2141449 PK04_097309 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P14 compound treatment 333150.0 -267000.0 -0.71 349530.0 -199000.0 -0.55 -0.8906 -0.9914 2144933 PK04_097310 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P15 compound treatment 349170.0 -251000.0 -0.67 316160.0 -232000.0 -0.64 -0.9252 -0.9997 2141416 PK04_097311 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P16 compound treatment 314420.0 -286000.0 -0.76 299900.0 -249000.0 -0.68 -1.0224 -0.9985 2144445 PK04_097312 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P17 compound treatment 349390.0 -251000.0 -0.67 365890.0 -183000.0 -0.5 -0.8282 -0.9899 2141453 PK04_097313 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P18 compound treatment 62030.0 -538000.0 -1.44 111640.0 -437000.0 -1.2 -1.8645 -0.996 2142745 PK04_097314 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P19 compound treatment 330190.0 -270000.0 -0.72 284900.0 -264000.0 -0.72 -1.0217 -1.0 2141541 PK04_097315 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P20 compound treatment 285230.0 -315000.0 -0.84 262330.0 -286000.0 -0.79 -1.1504 -0.9994 2142193 PK04_097316 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P21 compound treatment 294400.0 -306000.0 -0.82 257950.0 -291000.0 -0.8 -1.1416 -0.9999 2141134 PK04_097317 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P22 compound treatment 303570.0 -297000.0 -0.79 280440.0 -268000.0 -0.74 -1.0806 -0.9993 2142729 PK04_097318 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P23 compound treatment 303760.0 -296000.0 -0.79 317890.0 -231000.0 -0.63 -1.0076 -0.9939 2141121 PK04_097319 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2097 P24 compound treatment 331770.0 -268000.0 -0.72 352960.0 -196000.0 -0.54 -0.8866 -0.9899 2144273 PK04_097320 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A01 compound treatment 779700.0 182000.0 0.49 217680.0 -391000.0 -1.07 -0.4156 -0.3527 2141696 PK04_098001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A02 compound treatment 416990.0 -181000.0 -0.48 522720.0 -85900.0 -0.24 -0.5085 -0.9457 2144133 PK04_098002 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A03 compound treatment 804210.0 206000.0 0.55 706650.0 98000.0 0.27 0.5799 0.9456 2141089 PK04_098003 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A04 compound treatment 289480.0 -308000.0 -0.82 704610.0 96000.0 0.26 -0.3962 -0.4581 2142093 PK04_098004 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A05 compound treatment 227090.0 -371000.0 -0.99 405610.0 -203000.0 -0.56 -1.0945 -0.963 2141744 PK04_098005 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A06 compound treatment 307840.0 -290000.0 -0.77 471000.0 -138000.0 -0.38 -0.815 -0.9456 2143237 PK04_098006 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A07 compound treatment 273950.0 -324000.0 -0.87 324520.0 -284000.0 -0.78 -1.1634 -0.9987 2141337 PK04_098007 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A08 compound treatment 281600.0 -316000.0 -0.84 237710.0 -371000.0 -1.02 -1.3175 -0.9957 2144129 PK04_098008 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A09 compound treatment 699230.0 101000.0 0.27 361850.0 -247000.0 -0.68 -0.2877 -0.3943 2141791 PK04_098009 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A10 compound treatment 293890.0 -304000.0 -0.81 360510.0 -248000.0 -0.68 -1.0559 -0.9962 2144193 PK04_098010 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A11 compound treatment 266940.0 -331000.0 -0.88 300480.0 -308000.0 -0.85 -1.2233 -0.9998 2141133 PK04_098011 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A12 compound treatment 334170.0 -264000.0 -0.7 354330.0 -254000.0 -0.7 -0.9918 -1.0 2143993 PK04_098012 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A13 mock treatment 235230.0 -363000.0 -0.97 503680.0 -105000.0 -0.29 -0.8887 -0.8794 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A14 mock treatment 510630.0 -87200.0 -0.23 407490.0 -201000.0 -0.55 -0.5553 -0.9264 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A15 compound treatment 625920.0 28000.0 0.07 459170.0 -149000.0 -0.41 -0.2372 -0.5686 2141695 PK04_098013 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A16 compound treatment 534560.0 -63300.0 -0.17 399970.0 -209000.0 -0.57 -0.5247 -0.8783 2144913 PK04_098014 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A17 compound treatment 510640.0 -87200.0 -0.23 581150.0 -27500.0 -0.08 -0.2182 -0.8907 2141801 PK04_098015 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A18 compound treatment 553930.0 -43900.0 -0.12 535650.0 -73000.0 -0.2 -0.2247 -0.9675 2142117 PK04_098016 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A19 compound treatment 441230.0 -157000.0 -0.42 441280.0 -167000.0 -0.46 -0.6208 -0.9989 2141835 PK04_098017 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A20 compound treatment 406780.0 -191000.0 -0.51 391590.0 -217000.0 -0.6 -0.7823 -0.997 2144205 PK04_098018 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A21 compound treatment 242190.0 -356000.0 -0.95 318400.0 -290000.0 -0.8 -1.2352 -0.9962 2141920 PK04_098019 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A22 compound treatment 559810.0 -38100.0 -0.1 541250.0 -67400.0 -0.19 -0.2027 -0.9602 2141945 PK04_098020 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A23 compound treatment 379570.0 -218000.0 -0.58 589630.0 -19000.0 -0.05 -0.4492 -0.7674 2141111 PK04_098021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 A24 compound treatment 229650.0 -368000.0 -0.98 318770.0 -290000.0 -0.8 -1.2582 -0.9945 2143385 PK04_098022 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B01 compound treatment 433640.0 -164000.0 -0.44 670360.0 61700.0 0.17 -0.1904 -0.4049 2142845 PK04_098023 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B02 compound treatment 611770.0 13900.0 0.04 363270.0 -245000.0 -0.67 -0.4501 -0.6671 2143009 PK04_098024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B03 compound treatment 471810.0 -126000.0 -0.34 723260.0 115000.0 0.31 -0.0156 -0.0339 2144209 PK04_098025 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B04 compound treatment 736110.0 138000.0 0.37 444990.0 -164000.0 -0.45 -0.0566 -0.0974 2142037 PK04_098026 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B05 compound treatment 474410.0 -123000.0 -0.33 478370.0 -130000.0 -0.36 -0.4861 -0.9992 2144313 PK04_098027 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B06 compound treatment 355320.0 -243000.0 -0.65 513600.0 -95100.0 -0.26 -0.6426 -0.9201 2143245 PK04_098028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B07 compound treatment 613180.0 15300.0 0.04 590790.0 -17900.0 -0.05 -0.0058 -0.0904 2144661 PK04_098029 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B08 compound treatment 533680.0 -64200.0 -0.17 392370.0 -216000.0 -0.59 -0.5411 -0.8755 2143409 PK04_098030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B09 compound treatment 612010.0 14100.0 0.04 420970.0 -188000.0 -0.52 -0.3377 -0.6535 2144745 PK04_098031 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B10 compound treatment 494300.0 -104000.0 -0.28 494920.0 -114000.0 -0.31 -0.4164 -0.9982 2143049 PK04_098032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B11 compound treatment 638680.0 40800.0 0.11 415840.0 -193000.0 -0.53 -0.2972 -0.55 2143257 PK04_098033 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B12 compound treatment 464900.0 -133000.0 -0.36 270140.0 -339000.0 -0.93 -0.9083 -0.9129 2141502 PK04_098034 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B13 mock treatment 598400.0 529.0 0.0 433970.0 -175000.0 -0.48 -0.3381 -0.705 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B14 mock treatment 470630.0 -127000.0 -0.34 601450.0 -7210.0 -0.02 -0.2543 -0.747 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B15 compound treatment 604370.0 6500.0 0.02 549680.0 -59000.0 -0.16 -0.1022 -0.6277 2142113 PK04_098035 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B16 compound treatment 534140.0 -63700.0 -0.17 427680.0 -181000.0 -0.5 -0.4717 -0.8981 2141859 PK04_098036 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B17 compound treatment 421210.0 -177000.0 -0.47 413980.0 -195000.0 -0.53 -0.7116 -0.9981 2144033 PK04_098037 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B18 compound treatment 655130.0 57300.0 0.15 444110.0 -165000.0 -0.45 -0.2113 -0.443 2141540 PK04_098038 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B19 compound treatment 505690.0 -92200.0 -0.25 483580.0 -125000.0 -0.34 -0.4169 -0.9867 2144437 PK04_098039 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B20 compound treatment 240670.0 -357000.0 -0.95 223120.0 -386000.0 -1.06 -1.4231 -0.9987 2144725 PK04_098040 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B21 compound treatment 466990.0 -131000.0 -0.35 562100.0 -46600.0 -0.13 -0.3376 -0.9069 2143413 PK04_098041 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B22 compound treatment 491650.0 -106000.0 -0.28 618810.0 10200.0 0.03 -0.1809 -0.6346 2141509 PK04_098042 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B23 compound treatment 547960.0 -49900.0 -0.13 541090.0 -67600.0 -0.19 -0.2254 -0.9869 2142009 PK04_098043 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 B24 compound treatment 566190.0 -31700.0 -0.08 634660.0 26000.0 0.07 -0.0094 -0.0845 2141342 PK04_098044 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C01 compound treatment 391590.0 -206000.0 -0.55 718730.0 110000.0 0.3 -0.1759 -0.2799 2141145 PK04_098045 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C02 compound treatment 680160.0 82300.0 0.22 332250.0 -276000.0 -0.76 -0.3812 -0.4825 2143097 PK04_098046 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C03 compound treatment 460610.0 -137000.0 -0.37 668330.0 59700.0 0.16 -0.1434 -0.3571 2141834 PK04_098047 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C04 compound treatment 317630.0 -280000.0 -0.75 280850.0 -328000.0 -0.9 -1.1657 -0.9958 2142605 PK04_098048 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C05 compound treatment 299850.0 -298000.0 -0.8 579220.0 -29400.0 -0.08 -0.62 -0.7749 2141398 PK04_098049 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C06 compound treatment 327710.0 -270000.0 -0.72 560130.0 -48500.0 -0.13 -0.6045 -0.8237 2143013 PK04_098050 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C07 compound treatment 374400.0 -223000.0 -0.6 428770.0 -180000.0 -0.49 -0.7713 -0.9956 2141793 PK04_098051 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C08 compound treatment 510730.0 -87100.0 -0.23 594510.0 -14100.0 -0.04 -0.192 -0.8139 2143277 PK04_098052 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C09 compound treatment 324320.0 -274000.0 -0.73 272870.0 -336000.0 -0.92 -1.1685 -0.9934 2141681 PK04_098053 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C10 compound treatment 154730.0 -443000.0 -1.18 198150.0 -411000.0 -1.13 -1.6339 -0.9997 2144125 PK04_098054 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C11 mock treatment 351550.0 -246000.0 -0.66 415840.0 -193000.0 -0.53 -0.8395 -0.9942 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C12 mock treatment 471620.0 -126000.0 -0.34 263380.0 -345000.0 -0.95 -0.9087 -0.9032 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C13 compound treatment 306910.0 -291000.0 -0.78 313010.0 -296000.0 -0.81 -1.1235 -0.9998 2141376 PK04_098055 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C14 compound treatment 642560.0 44700.0 0.12 628240.0 19600.0 0.05 0.1224 0.9351 2143897 PK04_098056 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C15 mock treatment 497240.0 -101000.0 -0.27 495260.0 -113000.0 -0.31 -0.4102 -0.9973 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C16 mock treatment 487710.0 -110000.0 -0.29 660750.0 52100.0 0.14 -0.1069 -0.3269 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C17 compound treatment 496270.0 -102000.0 -0.27 584100.0 -24600.0 -0.07 -0.2396 -0.8567 2141461 PK04_098057 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C18 compound treatment 420590.0 -177000.0 -0.47 392590.0 -216000.0 -0.59 -0.7543 -0.9938 2143145 PK04_098058 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C19 compound treatment 266990.0 -331000.0 -0.88 318440.0 -290000.0 -0.8 -1.1883 -0.9987 2141551 PK04_098059 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C20 compound treatment 404560.0 -193000.0 -0.52 584890.0 -23800.0 -0.07 -0.4112 -0.7902 2144941 PK04_098060 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C21 compound treatment 232590.0 -365000.0 -0.98 342690.0 -266000.0 -0.73 -1.2062 -0.9898 2141535 PK04_098061 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C22 compound treatment 451380.0 -146000.0 -0.39 501340.0 -107000.0 -0.29 -0.485 -0.9902 2142185 PK04_098062 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C23 compound treatment 648000.0 50100.0 0.13 626610.0 18000.0 0.05 0.1295 0.9078 2141425 PK04_098063 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 C24 compound treatment 466490.0 -131000.0 -0.35 454510.0 -154000.0 -0.42 -0.5474 -0.9957 2144353 PK04_098064 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D01 compound treatment 320980.0 -277000.0 -0.74 387740.0 -221000.0 -0.61 -0.9518 -0.9952 2143317 PK04_098065 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D02 compound treatment 381560.0 -216000.0 -0.58 357990.0 -251000.0 -0.69 -0.8952 -0.9962 2144805 PK04_098066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D03 compound treatment 780800.0 183000.0 0.49 372720.0 -236000.0 -0.65 -0.1125 -0.1387 2142937 PK04_098067 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D04 compound treatment 689670.0 91800.0 0.25 423650.0 -185000.0 -0.51 -0.1858 -0.3294 2141997 PK04_098068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D05 compound treatment 548200.0 -49700.0 -0.13 278940.0 -330000.0 -0.91 -0.7339 -0.8022 2144781 PK04_098069 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D06 compound treatment 252520.0 -345000.0 -0.92 209150.0 -400000.0 -1.1 -1.4278 -0.9963 2144025 PK04_098070 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D07 compound treatment 567680.0 -30200.0 -0.08 328200.0 -280000.0 -0.77 -0.6015 -0.7769 2144817 PK04_098071 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D08 compound treatment 422760.0 -175000.0 -0.47 348390.0 -260000.0 -0.71 -0.836 -0.9789 2144197 PK04_098072 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D09 compound treatment 402780.0 -195000.0 -0.52 401130.0 -208000.0 -0.57 -0.7713 -0.999 2144761 PK04_098073 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D10 compound treatment 298300.0 -300000.0 -0.8 327720.0 -281000.0 -0.77 -1.1112 -0.9998 2142125 PK04_098074 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D11 mock treatment 778160.0 180000.0 0.48 391160.0 -217000.0 -0.6 -0.0817 -0.1065 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D12 mock treatment 372550.0 -225000.0 -0.6 786840.0 178000.0 0.49 -0.0796 -0.1027 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D13 compound treatment 552430.0 -45400.0 -0.12 653630.0 45000.0 0.12 0.0015 0.0086 2143225 PK04_098075 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D14 compound treatment 481990.0 -116000.0 -0.31 478730.0 -130000.0 -0.36 -0.4711 -0.9975 2144233 PK04_098076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D15 mock treatment 575620.0 -22300.0 -0.06 792350.0 184000.0 0.5 0.3146 0.6195 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D16 mock treatment 719100.0 121000.0 0.32 431530.0 -177000.0 -0.49 -0.1149 -0.1967 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D17 compound treatment 698520.0 101000.0 0.27 385880.0 -223000.0 -0.61 -0.2424 -0.3628 2143045 PK04_098077 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D18 compound treatment 603200.0 5330.0 0.01 621380.0 12700.0 0.03 0.0348 0.9217 2142013 PK04_098078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D19 compound treatment 573920.0 -24000.0 -0.06 553660.0 -55000.0 -0.15 -0.152 -0.9269 2142213 PK04_098079 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D20 compound treatment 720850.0 123000.0 0.33 733450.0 125000.0 0.34 0.4745 0.9998 2141447 PK04_098080 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D21 compound treatment 436880.0 -161000.0 -0.43 481190.0 -127000.0 -0.35 -0.5515 -0.9948 2143393 PK04_098081 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D22 compound treatment 690890.0 93000.0 0.25 643700.0 35000.0 0.1 0.2437 0.9147 2065844 PK04_098082 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D23 compound treatment 577500.0 -20400.0 -0.05 636880.0 28200.0 0.08 0.0163 0.1723 2144185 PK04_098083 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 D24 compound treatment 514580.0 -83300.0 -0.22 447630.0 -161000.0 -0.44 -0.4699 -0.9495 2141197 PK04_098084 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E01 mock treatment 665780.0 67900.0 0.18 767070.0 158000.0 0.43 0.4358 0.9248 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E02 mock treatment 793370.0 195000.0 0.52 804640.0 196000.0 0.54 0.7497 0.9999 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E03 compound treatment 613140.0 15300.0 0.04 613950.0 5290.0 0.01 0.0391 0.9034 2141526 PK04_098085 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E04 compound treatment 826940.0 229000.0 0.61 596160.0 -12500.0 -0.03 0.4084 0.6664 2142637 PK04_098086 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E05 compound treatment 809490.0 212000.0 0.57 499760.0 -109000.0 -0.3 0.1883 0.2944 2141181 PK04_098087 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E06 compound treatment 512970.0 -84900.0 -0.23 413920.0 -195000.0 -0.53 -0.5384 -0.9271 2142777 PK04_098088 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E07 compound treatment 519260.0 -78600.0 -0.21 340610.0 -268000.0 -0.74 -0.6688 -0.874 2141090 PK04_098089 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E08 compound treatment 496040.0 -102000.0 -0.27 525930.0 -82700.0 -0.23 -0.3529 -0.996 2144801 PK04_098090 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E09 mock treatment 284800.0 -313000.0 -0.84 736110.0 127000.0 0.35 -0.3439 -0.3793 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E10 mock treatment 416240.0 -182000.0 -0.49 392380.0 -216000.0 -0.59 -0.7629 -0.995 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E11 compound treatment 633560.0 35700.0 0.1 498180.0 -110000.0 -0.3 -0.1471 -0.4626 2141328 PK04_098091 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E12 compound treatment 191520.0 -406000.0 -1.09 234410.0 -374000.0 -1.03 -1.494 -0.9996 2144117 PK04_098092 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E13 compound treatment 354890.0 -243000.0 -0.65 433610.0 -175000.0 -0.48 -0.7987 -0.9891 2141750 PK04_098093 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E14 compound treatment 466400.0 -131000.0 -0.35 468430.0 -140000.0 -0.38 -0.5205 -0.9989 2142133 PK04_098094 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E15 compound treatment 430400.0 -167000.0 -0.45 723530.0 115000.0 0.32 -0.0933 -0.1705 2141837 PK04_098095 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E16 compound treatment 606280.0 8410.0 0.02 655300.0 46600.0 0.13 0.1064 0.8186 2143333 PK04_098096 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E17 mock treatment 594310.0 -3560.0 -0.01 799940.0 191000.0 0.53 0.3646 0.6942 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E18 mock treatment 716290.0 118000.0 0.32 567550.0 -41100.0 -0.11 0.1439 0.4284 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E19 compound treatment 423130.0 -175000.0 -0.47 319930.0 -289000.0 -0.79 -0.8905 -0.9681 2141392 PK04_098097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E20 compound treatment 631140.0 33300.0 0.09 519310.0 -89300.0 -0.25 -0.1106 -0.424 2144457 PK04_098098 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E21 compound treatment 517200.0 -80700.0 -0.22 576870.0 -31800.0 -0.09 -0.2141 -0.9208 2141783 PK04_098099 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E22 compound treatment 588040.0 -9830.0 -0.03 601780.0 -6880.0 -0.02 -0.0319 -0.9869 2142073 PK04_098100 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E23 compound treatment 463650.0 -134000.0 -0.36 557770.0 -50900.0 -0.14 -0.3523 -0.9156 2141929 PK04_098101 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 E24 compound treatment 606560.0 8690.0 0.02 608080.0 -578.0 0.0 0.0153 0.6573 2141993 PK04_098102 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F01 mock treatment 384960.0 -213000.0 -0.57 629680.0 21000.0 0.06 -0.3613 -0.6321 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F02 mock treatment 603420.0 5550.0 0.01 172120.0 -437000.0 -1.2 -0.837 -0.6983 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F03 compound treatment 578190.0 -19700.0 -0.05 710340.0 102000.0 0.28 0.1602 0.564 2142917 PK04_098103 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F04 compound treatment 317680.0 -280000.0 -0.75 285170.0 -323000.0 -0.89 -1.1572 -0.9964 2142953 PK04_098104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F05 compound treatment 291480.0 -306000.0 -0.82 222150.0 -387000.0 -1.06 -1.329 -0.9918 2144897 PK04_098105 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F06 compound treatment 553200.0 -44700.0 -0.12 818740.0 210000.0 0.58 0.3235 0.5492 2144329 PK04_098106 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F07 compound treatment 479570.0 -118000.0 -0.32 420930.0 -188000.0 -0.52 -0.5879 -0.9724 2144721 PK04_098107 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F08 compound treatment 359210.0 -239000.0 -0.64 512490.0 -96200.0 -0.26 -0.6374 -0.9239 2143969 PK04_098108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F09 mock treatment 840910.0 243000.0 0.65 428510.0 -180000.0 -0.49 0.1093 0.1339 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F10 mock treatment 782720.0 185000.0 0.49 779400.0 171000.0 0.47 0.6806 0.9997 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F11 compound treatment 407040.0 -191000.0 -0.51 403280.0 -205000.0 -0.56 -0.7591 -0.9987 2141973 PK04_098109 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F12 compound treatment 390030.0 -208000.0 -0.56 273820.0 -335000.0 -0.92 -1.0426 -0.9708 2141515 PK04_098110 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F13 compound treatment 446110.0 -152000.0 -0.41 397090.0 -212000.0 -0.58 -0.6973 -0.9845 2144053 PK04_098111 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F14 compound treatment 561760.0 -36100.0 -0.1 535000.0 -73700.0 -0.2 -0.2112 -0.9426 2143249 PK04_098112 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F15 compound treatment 422990.0 -175000.0 -0.47 414600.0 -194000.0 -0.53 -0.707 -0.9979 2144873 PK04_098113 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F16 compound treatment 459130.0 -139000.0 -0.37 380640.0 -228000.0 -0.63 -0.7047 -0.9687 2141199 PK04_098114 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F17 mock treatment 604870.0 7000.0 0.02 526900.0 -81800.0 -0.22 -0.1455 -0.646 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F18 mock treatment 801510.0 204000.0 0.54 662640.0 54000.0 0.15 0.4894 0.8681 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F19 compound treatment 394670.0 -203000.0 -0.54 392240.0 -216000.0 -0.59 -0.8039 -0.999 2142825 PK04_098115 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F20 compound treatment 556420.0 -41500.0 -0.11 537240.0 -71400.0 -0.2 -0.2169 -0.9634 2144217 PK04_098116 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F21 compound treatment 589200.0 -8670.0 -0.02 630890.0 22200.0 0.06 0.0268 0.4103 2144057 PK04_098117 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F22 compound treatment 569340.0 -28500.0 -0.08 680060.0 71400.0 0.2 0.0847 0.4029 2141689 PK04_098118 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F23 compound treatment 311970.0 -286000.0 -0.76 232000.0 -377000.0 -1.03 -1.2712 -0.9889 2144037 PK04_098119 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 F24 compound treatment 619040.0 21200.0 0.06 553700.0 -55000.0 -0.15 -0.0667 -0.414 2141464 PK04_098120 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G01 compound treatment 433360.0 -165000.0 -0.44 358080.0 -251000.0 -0.69 -0.7972 -0.9765 2141573 PK04_098121 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G02 compound treatment 420510.0 -177000.0 -0.47 382900.0 -226000.0 -0.62 -0.7732 -0.9912 2144113 PK04_098122 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G03 mock treatment 567240.0 -30600.0 -0.08 738330.0 130000.0 0.36 0.1939 0.5308 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G04 mock treatment 711240.0 113000.0 0.3 749850.0 141000.0 0.39 0.4882 0.9925 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G05 compound treatment 414680.0 -183000.0 -0.49 646480.0 37800.0 0.1 -0.2726 -0.5449 2141531 PK04_098123 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G06 compound treatment 161330.0 -437000.0 -1.17 77770.0 -531000.0 -1.46 -1.8551 -0.9939 2143985 PK04_098124 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G07 compound treatment 532590.0 -65300.0 -0.17 467370.0 -141000.0 -0.39 -0.3976 -0.9349 2065843 PK04_098125 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G08 compound treatment 397710.0 -200000.0 -0.53 280500.0 -328000.0 -0.9 -1.0151 -0.969 2144713 PK04_098126 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G09 compound treatment 380830.0 -217000.0 -0.58 488990.0 -120000.0 -0.33 -0.6422 -0.9638 2141779 PK04_098127 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G10 compound treatment 453540.0 -144000.0 -0.39 596560.0 -12100.0 -0.03 -0.2961 -0.7652 2142633 PK04_098128 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G11 compound treatment 15220.0 -583000.0 -1.56 15870.0 -593000.0 -1.63 -2.2512 -0.9998 2141711 PK04_098129 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G12 compound treatment 370350.0 -228000.0 -0.61 441670.0 -167000.0 -0.46 -0.7539 -0.9903 2142689 PK04_098130 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G13 compound treatment 781180.0 183000.0 0.49 305680.0 -303000.0 -0.83 -0.242 -0.2507 2141802 PK04_098131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G14 compound treatment 385760.0 -212000.0 -0.57 415800.0 -193000.0 -0.53 -0.775 -0.9994 2142905 PK04_098132 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G15 compound treatment 594240.0 -3630.0 -0.01 445850.0 -163000.0 -0.45 -0.3229 -0.7223 2141192 PK04_098133 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G16 compound treatment 471920.0 -126000.0 -0.34 442950.0 -166000.0 -0.45 -0.5596 -0.989 2142129 PK04_098134 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G17 compound treatment 275520.0 -322000.0 -0.86 310240.0 -298000.0 -0.82 -1.1881 -0.9997 2141728 PK04_098135 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G18 compound treatment 494310.0 -104000.0 -0.28 557890.0 -50800.0 -0.14 -0.2941 -0.9497 2144641 PK04_098136 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G19 mock treatment 548350.0 -49500.0 -0.13 630730.0 22100.0 0.06 -0.0507 -0.3483 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G20 mock treatment 757250.0 159000.0 0.43 588910.0 -19700.0 -0.05 0.2627 0.6121 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G21 compound treatment 607800.0 9930.0 0.03 510260.0 -98400.0 -0.27 -0.1723 -0.6346 2141885 PK04_098137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G22 compound treatment 635100.0 37200.0 0.1 610560.0 1900.0 0.01 0.074 0.7432 2144357 PK04_098138 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G23 compound treatment 473410.0 -124000.0 -0.33 683720.0 75100.0 0.21 -0.0893 -0.2284 2141361 PK04_098139 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 G24 compound treatment 540160.0 -57700.0 -0.15 437180.0 -171000.0 -0.47 -0.4419 -0.892 2142625 PK04_098140 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H01 compound treatment 525610.0 -72300.0 -0.19 549700.0 -59000.0 -0.16 -0.2509 -0.9962 2142737 PK04_098141 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H02 compound treatment 456660.0 -141000.0 -0.38 506830.0 -102000.0 -0.28 -0.4644 -0.9891 2144017 PK04_098142 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H03 mock treatment 273010.0 -325000.0 -0.87 438970.0 -170000.0 -0.47 -0.943 -0.9575 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H04 mock treatment 484990.0 -113000.0 -0.3 814840.0 206000.0 0.57 0.1871 0.2917 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H05 compound treatment 274880.0 -323000.0 -0.86 357020.0 -252000.0 -0.69 -1.0985 -0.9939 2143493 PK04_098143 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H06 compound treatment 242690.0 -355000.0 -0.95 451930.0 -157000.0 -0.43 -0.9751 -0.936 2141857 PK04_098144 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H07 compound treatment 461060.0 -137000.0 -0.37 364030.0 -245000.0 -0.67 -0.7333 -0.9591 2143497 PK04_098145 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H08 compound treatment 523740.0 -74100.0 -0.2 436960.0 -172000.0 -0.47 -0.4733 -0.9258 2141183 PK04_098146 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H09 compound treatment 619450.0 21600.0 0.06 661700.0 53000.0 0.15 0.1437 0.9177 2143289 PK04_098147 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H10 compound treatment 464450.0 -133000.0 -0.36 558490.0 -50200.0 -0.14 -0.3494 -0.9145 2142033 PK04_098148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H11 compound treatment 339440.0 -258000.0 -0.69 248040.0 -361000.0 -0.99 -1.1882 -0.9845 2143345 PK04_098149 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H12 compound treatment 385120.0 -213000.0 -0.57 474720.0 -134000.0 -0.37 -0.6618 -0.9778 2141965 PK04_098150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H13 compound treatment 528280.0 -69600.0 -0.19 495890.0 -113000.0 -0.31 -0.3504 -0.9702 2142053 PK04_098151 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H14 compound treatment 568430.0 -29400.0 -0.08 536380.0 -72300.0 -0.2 -0.1959 -0.9179 2143285 PK04_098152 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H15 compound treatment 458910.0 -139000.0 -0.37 465790.0 -143000.0 -0.39 -0.5398 -0.9996 2143953 PK04_098153 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H16 compound treatment 352990.0 -245000.0 -0.65 491520.0 -117000.0 -0.32 -0.6899 -0.9465 2142849 PK04_098154 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H17 compound treatment 599550.0 1680.0 0.0 496230.0 -112000.0 -0.31 -0.2151 -0.6968 2142197 PK04_098155 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H18 compound treatment 376970.0 -221000.0 -0.59 412120.0 -197000.0 -0.54 -0.7987 -0.999 2141678 PK04_098156 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H19 mock treatment 469930.0 -128000.0 -0.34 707520.0 98900.0 0.27 -0.0497 -0.1139 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H20 mock treatment 553700.0 -44200.0 -0.12 812580.0 204000.0 0.56 0.3125 0.5461 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H21 compound treatment 736110.0 138000.0 0.37 569360.0 -39300.0 -0.11 0.1848 0.4804 2142657 PK04_098157 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H22 compound treatment 453000.0 -145000.0 -0.39 430510.0 -178000.0 -0.49 -0.6195 -0.9933 2141194 PK04_098158 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H23 compound treatment 670560.0 72700.0 0.19 403800.0 -205000.0 -0.56 -0.2604 -0.4377 2142665 PK04_098159 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 H24 compound treatment 415400.0 -182000.0 -0.49 790240.0 182000.0 0.5 0.0079 0.0113 2141813 PK04_098160 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I01 compound treatment 351600.0 -246000.0 -0.66 314520.0 -294000.0 -0.81 -1.0361 -0.9948 2141395 PK04_098161 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I02 compound treatment 309990.0 -288000.0 -0.77 267360.0 -341000.0 -0.94 -1.2063 -0.9952 2144813 PK04_098162 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I03 compound treatment 231450.0 -366000.0 -0.98 298740.0 -310000.0 -0.85 -1.2937 -0.9976 2141107 PK04_098163 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I04 compound treatment 314880.0 -283000.0 -0.76 529570.0 -79100.0 -0.22 -0.688 -0.8748 2142597 PK04_098164 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I05 mock treatment 548320.0 -49600.0 -0.13 466310.0 -142000.0 -0.39 -0.3699 -0.8966 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I06 mock treatment 299610.0 -298000.0 -0.8 440330.0 -168000.0 -0.46 -0.8901 -0.9665 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I07 compound treatment 381280.0 -217000.0 -0.58 375420.0 -233000.0 -0.64 -0.8619 -0.9987 2141144 PK04_098165 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I08 compound treatment 652220.0 54300.0 0.15 491200.0 -117000.0 -0.32 -0.1254 -0.3545 2142693 PK04_098166 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I09 compound treatment 601070.0 3200.0 0.01 385390.0 -223000.0 -0.61 -0.4274 -0.6972 2141896 PK04_098167 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I10 compound treatment 450880.0 -147000.0 -0.39 458500.0 -150000.0 -0.41 -0.5691 -0.9997 2141957 PK04_098168 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I11 compound treatment 351380.0 -246000.0 -0.66 494480.0 -114000.0 -0.31 -0.6872 -0.9424 2141394 PK04_098169 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I12 compound treatment 361520.0 -236000.0 -0.63 342180.0 -266000.0 -0.73 -0.9637 -0.9973 2142049 PK04_098170 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I13 compound treatment 652270.0 54400.0 0.15 662310.0 53700.0 0.15 0.2069 1.0 2141346 PK04_098171 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I14 compound treatment 383410.0 -214000.0 -0.57 455160.0 -153000.0 -0.42 -0.703 -0.9886 2143477 PK04_098172 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I15 compound treatment 124250.0 -474000.0 -1.27 352170.0 -256000.0 -0.7 -1.3924 -0.9618 2141373 PK04_098173 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I16 compound treatment 450180.0 -148000.0 -0.39 509120.0 -99500.0 -0.27 -0.4722 -0.9839 2144645 PK04_098174 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I17 compound treatment 524340.0 -73500.0 -0.2 579570.0 -29100.0 -0.08 -0.1953 -0.9214 2141116 PK04_098175 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I18 compound treatment 402260.0 -196000.0 -0.52 347260.0 -261000.0 -0.72 -0.8769 -0.9878 2142097 PK04_098176 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I19 compound treatment 643720.0 45800.0 0.12 665410.0 56800.0 0.16 0.1968 0.9929 2141442 PK04_098177 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I20 compound treatment 587860.0 -10000.0 -0.03 703040.0 94400.0 0.26 0.1643 0.6308 2142005 PK04_098178 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I21 mock treatment 745520.0 148000.0 0.39 651470.0 42800.0 0.12 0.362 0.8796 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I22 mock treatment 505470.0 -92400.0 -0.25 472890.0 -136000.0 -0.37 -0.4381 -0.98 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I23 compound treatment 491380.0 -106000.0 -0.28 437380.0 -171000.0 -0.47 -0.5336 -0.971 2141137 PK04_098179 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 I24 compound treatment 405170.0 -193000.0 -0.51 467620.0 -141000.0 -0.39 -0.6377 -0.9902 2144905 PK04_098180 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J01 compound treatment 427850.0 -170000.0 -0.45 395060.0 -214000.0 -0.59 -0.7358 -0.992 2142853 PK04_098181 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J02 compound treatment 644760.0 46900.0 0.13 522770.0 -85900.0 -0.24 -0.0782 -0.2928 2141434 PK04_098182 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J03 compound treatment 379200.0 -219000.0 -0.58 603230.0 -5430.0 -0.01 -0.4235 -0.7249 2142925 PK04_098183 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J04 compound treatment 604160.0 6290.0 0.02 563320.0 -45300.0 -0.12 -0.0761 -0.6062 2141810 PK04_098184 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J05 mock treatment 503520.0 -94400.0 -0.25 586680.0 -22000.0 -0.06 -0.2209 -0.8523 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J06 mock treatment 359940.0 -238000.0 -0.64 203520.0 -405000.0 -1.11 -1.2359 -0.9648 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J07 compound treatment 405920.0 -192000.0 -0.51 339470.0 -269000.0 -0.74 -0.8851 -0.984 2143253 PK04_098185 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J08 compound treatment 438450.0 -159000.0 -0.43 444550.0 -164000.0 -0.45 -0.6197 -0.9996 2141219 PK04_098186 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J09 compound treatment 562770.0 -35100.0 -0.09 572570.0 -36100.0 -0.1 -0.1364 -0.9996 2142945 PK04_098187 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J10 compound treatment 706420.0 109000.0 0.29 796980.0 188000.0 0.52 0.5706 0.9626 2141450 PK04_098188 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J11 compound treatment 220450.0 -377000.0 -1.01 486150.0 -123000.0 -0.34 -0.9506 -0.8945 2144285 PK04_098189 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J12 compound treatment 289850.0 -308000.0 -0.82 358400.0 -250000.0 -0.69 -1.0676 -0.996 2141139 PK04_098190 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J13 compound treatment 449120.0 -149000.0 -0.4 567530.0 -41100.0 -0.11 -0.3608 -0.8735 2143473 PK04_098191 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J14 compound treatment 376970.0 -221000.0 -0.59 416000.0 -193000.0 -0.53 -0.7912 -0.9985 2144013 PK04_098192 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J15 compound treatment 509080.0 -88800.0 -0.24 371410.0 -237000.0 -0.65 -0.6283 -0.9064 2142837 PK04_098193 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J16 compound treatment 678410.0 80500.0 0.22 658660.0 50000.0 0.14 0.2492 0.9765 2141784 PK04_098194 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J17 compound treatment 601810.0 3940.0 0.01 590680.0 -18000.0 -0.05 -0.0275 -0.5441 2144425 PK04_098195 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J18 compound treatment 400650.0 -197000.0 -0.53 363430.0 -245000.0 -0.67 -0.8485 -0.9926 2141332 PK04_098196 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J19 compound treatment 491650.0 -106000.0 -0.28 533830.0 -74800.0 -0.21 -0.3459 -0.9874 2143957 PK04_098197 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J20 compound treatment 725330.0 127000.0 0.34 713250.0 105000.0 0.29 0.4438 0.9964 2141933 PK04_098198 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J21 mock treatment 736770.0 139000.0 0.37 588160.0 -20500.0 -0.06 0.2225 0.5931 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J22 mock treatment 779160.0 181000.0 0.48 699230.0 90600.0 0.25 0.5182 0.952 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J23 compound treatment 348740.0 -249000.0 -0.67 474880.0 -134000.0 -0.37 -0.7302 -0.9608 2144049 PK04_098199 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 J24 compound treatment 499110.0 -98800.0 -0.26 600370.0 -8290.0 -0.02 -0.2026 -0.7653 2141196 PK04_098200 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K01 compound treatment 588710.0 -9160.0 -0.02 539040.0 -69600.0 -0.19 -0.1525 -0.7912 2141522 PK04_098201 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K02 compound treatment 488880.0 -109000.0 -0.29 404340.0 -204000.0 -0.56 -0.6025 -0.9533 2142617 PK04_098202 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K03 compound treatment 898240.0 300000.0 0.8 631720.0 23100.0 0.06 0.6121 0.7605 2141439 PK04_098203 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K04 compound treatment 492800.0 -105000.0 -0.28 522140.0 -86500.0 -0.24 -0.3664 -0.9966 2143329 PK04_098204 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K05 compound treatment 213920.0 -384000.0 -1.03 207040.0 -402000.0 -1.1 -1.5048 -0.9993 2141725 PK04_098205 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K06 compound treatment 719680.0 122000.0 0.33 314750.0 -294000.0 -0.81 -0.3405 -0.3914 2142973 PK04_098206 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K07 mock treatment 254530.0 -343000.0 -0.92 613660.0 5000.0 0.01 -0.6387 -0.6964 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K08 mock treatment 304650.0 -293000.0 -0.78 549840.0 -58800.0 -0.16 -0.668 -0.8353 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K09 compound treatment 386720.0 -211000.0 -0.56 300270.0 -308000.0 -0.85 -0.9975 -0.9805 2141136 PK04_098207 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K10 compound treatment 876420.0 279000.0 0.74 400920.0 -208000.0 -0.57 0.1228 0.131 2143005 PK04_098208 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K11 compound treatment 272530.0 -325000.0 -0.87 246120.0 -363000.0 -1.0 -1.3183 -0.9977 2141925 PK04_098209 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K12 compound treatment 514450.0 -83400.0 -0.22 419640.0 -189000.0 -0.52 -0.5245 -0.9287 2144741 PK04_098210 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K13 compound treatment 699120.0 101000.0 0.27 342080.0 -267000.0 -0.73 -0.3263 -0.4182 2141147 PK04_098211 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K14 compound treatment 447200.0 -151000.0 -0.4 525960.0 -82700.0 -0.23 -0.4451 -0.9633 2143465 PK04_098212 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K15 mock treatment 595060.0 -2810.0 -0.01 550080.0 -58600.0 -0.16 -0.119 -0.7393 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K16 mock treatment 456270.0 -142000.0 -0.38 701600.0 92900.0 0.26 -0.087 -0.1907 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K17 compound treatment 597440.0 -431.0 0.0 485250.0 -123000.0 -0.34 -0.2404 -0.7095 2141530 PK04_098213 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K18 compound treatment 680980.0 83100.0 0.22 568740.0 -39900.0 -0.11 0.0795 0.321 2143169 PK04_098214 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K19 compound treatment 482640.0 -115000.0 -0.31 515380.0 -93300.0 -0.26 -0.3987 -0.9958 2141707 PK04_098215 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K20 compound treatment 534900.0 -63000.0 -0.17 600170.0 -8490.0 -0.02 -0.1354 -0.7975 2143073 PK04_098216 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K21 compound treatment 872350.0 274000.0 0.73 551690.0 -57000.0 -0.16 0.4078 0.544 2141428 PK04_098217 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K22 compound treatment 213680.0 -384000.0 -1.03 136500.0 -472000.0 -1.3 -1.6422 -0.9933 2142725 PK04_098218 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K23 mock treatment 768410.0 171000.0 0.46 766560.0 158000.0 0.43 0.6286 0.9997 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 K24 mock treatment 830950.0 233000.0 0.62 724190.0 116000.0 0.32 0.6645 0.951 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L01 compound treatment 656000.0 58100.0 0.16 727810.0 119000.0 0.33 0.3411 0.942 2143889 PK04_098219 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L02 compound treatment 549370.0 -48500.0 -0.13 210310.0 -398000.0 -1.09 -0.8649 -0.7854 2141700 PK04_098220 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L03 compound treatment 78580.0 -519000.0 -1.39 65530.0 -543000.0 -1.49 -2.0351 -0.9993 2142733 PK04_098221 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L04 compound treatment 460960.0 -137000.0 -0.37 454560.0 -154000.0 -0.42 -0.5577 -0.9974 2141934 PK04_098222 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L05 compound treatment 462880.0 -135000.0 -0.36 477340.0 -131000.0 -0.36 -0.5099 -1.0 2143873 PK04_098223 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L06 compound treatment 806310.0 208000.0 0.56 577450.0 -31200.0 -0.09 0.3331 0.5913 2141797 PK04_098224 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L07 mock treatment 870210.0 272000.0 0.73 659600.0 50900.0 0.14 0.6133 0.8279 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L08 mock treatment 332480.0 -265000.0 -0.71 670600.0 61900.0 0.17 -0.381 -0.5226 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L09 compound treatment 627060.0 29200.0 0.08 338460.0 -270000.0 -0.74 -0.4694 -0.6293 2142957 PK04_098225 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L10 compound treatment 770840.0 173000.0 0.46 403260.0 -205000.0 -0.56 -0.0721 -0.0988 3413983 PK04_098226 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L11 compound treatment 383950.0 -214000.0 -0.57 305460.0 -303000.0 -0.83 -0.9926 -0.9831 2142717 PK04_098227 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L12 compound treatment 715400.0 118000.0 0.31 449850.0 -159000.0 -0.44 -0.0863 -0.1607 3413985 PK04_098228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L13 compound treatment 775360.0 177000.0 0.47 457060.0 -152000.0 -0.42 0.0409 0.0649 2143357 PK04_098229 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L14 compound treatment 755480.0 158000.0 0.42 449130.0 -160000.0 -0.44 -0.012 -0.0198 3413987 PK04_098230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L15 mock treatment 749320.0 151000.0 0.4 636290.0 27600.0 0.08 0.3397 0.8253 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L16 mock treatment 690780.0 92900.0 0.25 581310.0 -27300.0 -0.08 0.1224 0.472 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L17 compound treatment 784220.0 186000.0 0.5 524530.0 -84100.0 -0.23 0.1886 0.3438 2143089 PK04_098231 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L18 compound treatment 672000.0 74100.0 0.2 618580.0 9920.0 0.03 0.1593 0.7969 3413990 PK04_098232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L19 compound treatment 704760.0 107000.0 0.29 501350.0 -107000.0 -0.29 -0.0064 -0.0157 2144137 PK04_098233 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L20 compound treatment 646240.0 48400.0 0.13 655330.0 46700.0 0.13 0.182 1.0 3413992 PK04_098234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L21 compound treatment 606490.0 8620.0 0.02 679250.0 70600.0 0.19 0.1533 0.7856 2143369 PK04_098235 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L22 compound treatment 507130.0 -90700.0 -0.24 496190.0 -112000.0 -0.31 -0.3897 -0.9928 3413998 PK04_098236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5cccc(Br)c5)C/C=C/C[C@@H](Cc6cccc(Br)c6)C(=O)O[C@@H]14 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L23 mock treatment 773880.0 176000.0 0.47 760250.0 152000.0 0.42 0.6267 0.9982 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 L24 mock treatment 808750.0 211000.0 0.56 732690.0 124000.0 0.34 0.6391 0.9709 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M01 compound treatment 783110.0 185000.0 0.49 480480.0 -128000.0 -0.35 0.101 0.1664 2141977 PK04_098237 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M02 compound treatment 500380.0 -97500.0 -0.26 508660.0 -100000.0 -0.27 -0.3783 -0.9997 2144277 PK04_098238 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M03 compound treatment 329730.0 -268000.0 -0.72 395170.0 -213000.0 -0.59 -0.9209 -0.995 2143353 PK04_098239 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M04 compound treatment 535860.0 -62000.0 -0.17 653660.0 45000.0 0.12 -0.0298 -0.144 2142753 PK04_098240 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M05 compound treatment 501760.0 -96100.0 -0.26 689330.0 80700.0 0.22 -0.0249 -0.0735 2142713 PK04_098241 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M06 compound treatment 377550.0 -220000.0 -0.59 450920.0 -158000.0 -0.43 -0.7223 -0.9886 2143893 PK04_098242 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M07 compound treatment 368820.0 -229000.0 -0.61 675160.0 66500.0 0.18 -0.3035 -0.4754 2143173 PK04_098243 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M08 compound treatment 670400.0 72500.0 0.19 615410.0 6750.0 0.02 0.1501 0.7712 2143913 PK04_098244 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M09 mock treatment 854080.0 256000.0 0.68 740160.0 132000.0 0.36 0.7392 0.9554 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M10 mock treatment 855130.0 257000.0 0.69 791150.0 182000.0 0.5 0.8402 0.988 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M11 compound treatment 428700.0 -169000.0 -0.45 349300.0 -259000.0 -0.71 -0.823 -0.9759 2143965 PK04_098245 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M12 compound treatment 613560.0 15700.0 0.04 464480.0 -144000.0 -0.4 -0.2503 -0.6287 2144453 PK04_098246 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M13 mock treatment 777240.0 179000.0 0.48 636260.0 27600.0 0.08 0.3924 0.8089 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M14 mock treatment 754590.0 157000.0 0.42 589230.0 -19400.0 -0.05 0.2583 0.6121 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M15 compound treatment 763040.0 165000.0 0.44 755210.0 147000.0 0.4 0.5965 0.9989 2142065 PK04_098247 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M16 compound treatment 674330.0 76500.0 0.2 695630.0 87000.0 0.24 0.3132 0.997 2143293 PK04_098248 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M17 compound treatment 536800.0 -61100.0 -0.16 566730.0 -41900.0 -0.12 -0.1967 -0.9854 2142857 PK04_098249 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M18 compound treatment 755480.0 158000.0 0.42 720250.0 112000.0 0.31 0.5143 0.9878 2142613 PK04_098250 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M19 compound treatment 708060.0 110000.0 0.29 523440.0 -85200.0 -0.23 0.0427 0.1135 2142697 PK04_098251 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M20 compound treatment 563430.0 -34400.0 -0.09 488050.0 -121000.0 -0.33 -0.2992 -0.8706 2144821 PK04_098252 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M21 compound treatment 803320.0 205000.0 0.55 642730.0 34100.0 0.09 0.4542 0.8159 2142965 PK04_098253 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M22 compound treatment 678990.0 81100.0 0.22 661140.0 52500.0 0.14 0.2551 0.9804 2144777 PK04_098254 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M23 compound treatment 764640.0 167000.0 0.45 659910.0 51300.0 0.14 0.4145 0.8873 2141143 PK04_098255 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 M24 compound treatment 594400.0 -3470.0 -0.01 729810.0 121000.0 0.33 0.2286 0.6871 2144937 PK04_098256 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N01 compound treatment 621280.0 23400.0 0.06 584990.0 -23700.0 -0.06 -0.0017 -0.0192 2144901 PK04_098257 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N02 compound treatment 629600.0 31700.0 0.08 646090.0 37400.0 0.1 0.1326 0.9954 3413999 PK04_098258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N03 compound treatment 749010.0 151000.0 0.4 692690.0 84000.0 0.23 0.4486 0.9648 2143297 PK04_098259 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N04 compound treatment 355950.0 -242000.0 -0.65 592480.0 -16200.0 -0.04 -0.4883 -0.7539 3414005 PK04_098260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N05 compound treatment 523930.0 -73900.0 -0.2 649490.0 40800.0 0.11 -0.0604 -0.2659 2142017 PK04_098261 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N06 compound treatment 799200.0 201000.0 0.54 311200.0 -297000.0 -0.82 -0.1972 -0.2017 3188747 PK04_098262 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)CCc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N07 compound treatment 833220.0 235000.0 0.63 576690.0 -32000.0 -0.09 0.3824 0.6025 2143017 PK04_098263 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N08 compound treatment 896760.0 299000.0 0.8 706910.0 98300.0 0.27 0.7552 0.8962 3188748 PK04_098264 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N09 mock treatment 868410.0 271000.0 0.72 828380.0 220000.0 0.6 0.9375 0.996 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N10 mock treatment 865860.0 268000.0 0.72 858280.0 250000.0 0.69 0.9907 0.9998 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N11 compound treatment 555910.0 -42000.0 -0.11 603310.0 -5350.0 -0.01 -0.0896 -0.793 2144265 PK04_098265 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N12 compound treatment 483840.0 -114000.0 -0.3 727320.0 119000.0 0.33 0.015 0.0336 3069249 PK04_098266 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3c(OC)cccc3OC)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N13 mock treatment 847750.0 250000.0 0.67 531710.0 -76900.0 -0.21 0.3226 0.4608 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N14 mock treatment 633960.0 36100.0 0.1 895700.0 287000.0 0.79 0.6254 0.7877 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N15 compound treatment 587520.0 -10400.0 -0.03 607120.0 -1540.0 0.0 -0.0225 -0.8057 2143165 PK04_098267 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N16 compound treatment 747280.0 149000.0 0.4 674740.0 66100.0 0.18 0.4105 0.9363 3188751 PK04_098268 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N17 compound treatment 729180.0 131000.0 0.35 717290.0 109000.0 0.3 0.4589 0.9967 2144365 PK04_098269 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N18 compound treatment 607730.0 9860.0 0.03 591170.0 -17500.0 -0.05 -0.0153 -0.2799 3188752 PK04_098270 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3cccc(F)c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N19 compound treatment 582720.0 -15200.0 -0.04 449070.0 -160000.0 -0.44 -0.3384 -0.7691 2142105 PK04_098271 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N20 compound treatment 621940.0 24100.0 0.06 550670.0 -58000.0 -0.16 -0.0671 -0.3909 3068687 PK04_098272 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(OC)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N21 compound treatment 518190.0 -79700.0 -0.21 709500.0 101000.0 0.28 0.0453 0.1297 2144245 PK04_098273 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N22 compound treatment 393620.0 -204000.0 -0.55 391960.0 -217000.0 -0.59 -0.8064 -0.9991 3068689 PK04_098274 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N23 compound treatment 676320.0 78400.0 0.21 496740.0 -112000.0 -0.31 -0.0691 -0.1858 2143153 PK04_098275 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 N24 compound treatment 387390.0 -210000.0 -0.56 371380.0 -237000.0 -0.65 -0.8582 -0.9973 3188876 PK04_098276 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O01 compound treatment 511700.0 -86200.0 -0.23 556440.0 -52200.0 -0.14 -0.2641 -0.974 2143373 PK04_098277 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O02 compound treatment 543270.0 -54600.0 -0.15 605600.0 -3060.0 -0.01 -0.1091 -0.7466 2142209 PK04_098278 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O03 compound treatment 669990.0 72100.0 0.19 510240.0 -98400.0 -0.27 -0.0548 -0.1653 2144345 PK04_098279 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O04 compound treatment 648840.0 51000.0 0.14 457080.0 -152000.0 -0.42 -0.198 -0.4522 2142673 PK04_098280 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O05 compound treatment 466810.0 -131000.0 -0.35 585210.0 -23400.0 -0.06 -0.293 -0.8233 2143977 PK04_098281 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O06 compound treatment 602920.0 5050.0 0.01 672320.0 63700.0 0.17 0.1331 0.7594 2142077 PK04_098282 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O07 compound treatment 331920.0 -266000.0 -0.71 536230.0 -72400.0 -0.2 -0.6429 -0.8715 2141985 PK04_098283 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O08 compound treatment 393020.0 -205000.0 -0.55 359460.0 -249000.0 -0.68 -0.8707 -0.9939 2143485 PK04_098284 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O09 compound treatment 598740.0 869.0 0.0 607690.0 -968.0 0.0 -2.0E-4 -0.067 2144665 PK04_098285 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O10 compound treatment 691750.0 93900.0 0.25 727330.0 119000.0 0.33 0.4077 0.9916 2143273 PK04_098286 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O11 mock treatment 800850.0 203000.0 0.54 682840.0 74200.0 0.2 0.5274 0.9106 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O12 mock treatment 414450.0 -183000.0 -0.49 589870.0 -18800.0 -0.05 -0.3829 -0.7773 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O13 compound treatment 573410.0 -24500.0 -0.07 522100.0 -86600.0 -0.24 -0.2142 -0.8693 2144773 PK04_098287 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O14 compound treatment 412840.0 -185000.0 -0.49 583370.0 -25300.0 -0.07 -0.3986 -0.7986 2143945 PK04_098288 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O15 compound treatment 675200.0 77300.0 0.21 477060.0 -132000.0 -0.36 -0.1094 -0.2629 2144317 PK04_098289 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O16 compound treatment 421120.0 -177000.0 -0.47 544380.0 -64300.0 -0.18 -0.4586 -0.9099 2143905 PK04_098290 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O17 compound treatment 630270.0 32400.0 0.09 578730.0 -29900.0 -0.08 0.0031 0.0259 2143917 PK04_098291 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O18 compound treatment 578170.0 -19700.0 -0.05 455380.0 -153000.0 -0.42 -0.3348 -0.7894 2144253 PK04_098292 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O19 compound treatment 326480.0 -271000.0 -0.72 340850.0 -268000.0 -0.74 -1.0325 -1.0 2144105 PK04_098293 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O20 compound treatment 588550.0 -9320.0 -0.02 444560.0 -164000.0 -0.45 -0.3362 -0.745 2144293 PK04_098294 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O21 compound treatment 669070.0 71200.0 0.19 574830.0 -33800.0 -0.09 0.0688 0.3251 2142997 PK04_098295 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O22 compound treatment 455780.0 -142000.0 -0.38 419270.0 -189000.0 -0.52 -0.636 -0.988 2144737 PK04_098296 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O23 compound treatment 726170.0 128000.0 0.34 481520.0 -127000.0 -0.35 -0.0045 -0.0092 2141452 PK04_098297 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 O24 compound treatment 631210.0 33300.0 0.09 522270.0 -86400.0 -0.24 -0.1047 -0.4134 2142677 PK04_098298 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P01 compound treatment 126570.0 -471000.0 -1.26 196480.0 -412000.0 -1.13 -1.6903 -0.9986 2144005 PK04_098299 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P02 compound treatment 139400.0 -458000.0 -1.22 165640.0 -443000.0 -1.22 -1.7259 -1.0 3068772 PK04_098300 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(C#N)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P03 compound treatment 351800.0 -246000.0 -0.66 330960.0 -278000.0 -0.76 -1.0038 -0.9973 2142593 PK04_098301 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P04 compound treatment 294730.0 -303000.0 -0.81 333170.0 -275000.0 -0.76 -1.1073 -0.9994 3000699 PK04_098302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P05 compound treatment 280730.0 -317000.0 -0.85 280040.0 -329000.0 -0.9 -1.2369 -0.9995 2144921 PK04_098303 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P06 compound treatment 317920.0 -280000.0 -0.75 478310.0 -130000.0 -0.36 -0.7818 -0.9431 3000700 PK04_098304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P07 compound treatment 455570.0 -142000.0 -0.38 475400.0 -133000.0 -0.37 -0.5275 -0.9998 2143937 PK04_098305 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P08 compound treatment 275450.0 -322000.0 -0.86 326770.0 -282000.0 -0.77 -1.1562 -0.9986 3000701 PK04_098306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P09 compound treatment 405120.0 -193000.0 -0.51 359790.0 -249000.0 -0.68 -0.8472 -0.9903 2144785 PK04_098307 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P10 compound treatment 375240.0 -223000.0 -0.59 352010.0 -257000.0 -0.7 -0.9187 -0.9964 3089322 PK04_098308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P11 mock treatment 375090.0 -223000.0 -0.6 406560.0 -202000.0 -0.55 -0.8131 -0.9994 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P12 mock treatment 379380.0 -218000.0 -0.58 416320.0 -192000.0 -0.53 -0.786 -0.9988 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P13 compound treatment 301060.0 -297000.0 -0.79 328960.0 -280000.0 -0.77 -1.1036 -0.9999 2144213 PK04_098309 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P14 compound treatment 267680.0 -330000.0 -0.88 394850.0 -214000.0 -0.59 -1.0387 -0.9804 3089323 PK04_098310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P15 compound treatment 281490.0 -316000.0 -0.85 525650.0 -83000.0 -0.23 -0.7587 -0.8668 2144225 PK04_098311 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P16 compound treatment 358610.0 -239000.0 -0.64 387420.0 -221000.0 -0.61 -0.8814 -0.9997 3000703 PK04_098312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P17 compound treatment 465050.0 -133000.0 -0.35 395810.0 -213000.0 -0.58 -0.6641 -0.9714 2141953 PK04_098313 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P18 compound treatment 284290.0 -314000.0 -0.84 307430.0 -301000.0 -0.83 -1.177 -1.0 3000704 PK04_098314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)c4cc5ccccc5[nH]4)[C@H]1OC(=O)c6cc7ccccc7[nH]6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P19 compound treatment 491060.0 -107000.0 -0.29 520050.0 -88600.0 -0.24 -0.3737 -0.9969 2143337 PK04_098315 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P20 compound treatment 333340.0 -265000.0 -0.71 255120.0 -354000.0 -0.97 -1.1859 -0.9878 3089326 PK04_098316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P21 compound treatment 331630.0 -266000.0 -0.71 401940.0 -207000.0 -0.57 -0.9041 -0.9938 2143233 PK04_098317 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P22 compound treatment 419540.0 -178000.0 -0.48 405140.0 -204000.0 -0.56 -0.7319 -0.9968 3089328 PK04_098318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P23 compound treatment 532090.0 -65800.0 -0.18 370560.0 -238000.0 -0.65 -0.5865 -0.8664 2142969 PK04_098319 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2098 P24 compound treatment 568000.0 -29900.0 -0.08 501710.0 -107000.0 -0.29 -0.264 -0.8678 3189006 PK04_098320 CC(C)[Si](OCCCNS(=O)(=O)c1ccc(Br)cc1)(C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A01 compound treatment 233390.0 -424000.0 -1.13 878340.0 308000.0 0.85 -0.2031 -0.1436 3052787 PK04_100001 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A02 compound treatment 662130.0 4330.0 0.01 345330.0 -225000.0 -0.62 -0.4281 -0.6937 3052649 PK04_100002 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A03 compound treatment 346600.0 -311000.0 -0.83 564800.0 -5250.0 -0.01 -0.598 -0.7193 3176622 PK04_100003 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A04 compound treatment 239310.0 -418000.0 -1.12 299090.0 -271000.0 -0.74 -1.3164 -0.9804 3175961 PK04_100004 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A05 compound treatment 886000.0 228000.0 0.61 276640.0 -293000.0 -0.81 -0.1386 -0.1372 3176556 PK04_100005 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A06 compound treatment 204170.0 -454000.0 -1.21 244880.0 -325000.0 -0.89 -1.488 -0.9887 3176630 PK04_100006 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A07 compound treatment 483390.0 -174000.0 -0.47 232220.0 -338000.0 -0.93 -0.9852 -0.9493 3175901 PK04_100007 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A08 compound treatment 460050.0 -198000.0 -0.53 406510.0 -164000.0 -0.45 -0.691 -0.9967 3176729 PK04_100008 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A09 compound treatment 715160.0 57400.0 0.15 457570.0 -112000.0 -0.31 -0.11 -0.3192 3052580 PK04_100009 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A10 compound treatment 385000.0 -273000.0 -0.73 595870.0 25800.0 0.07 -0.4651 -0.6353 3176731 PK04_100010 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A11 compound treatment 473500.0 -184000.0 -0.49 441560.0 -128000.0 -0.35 -0.5975 -0.9866 3176633 PK04_100011 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A12 compound treatment 429770.0 -228000.0 -0.61 457540.0 -113000.0 -0.31 -0.6491 -0.9505 3176445 PK04_100012 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A13 mock treatment 298640.0 -359000.0 -0.96 749700.0 180000.0 0.49 -0.3296 -0.3055 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A14 mock treatment 451900.0 -206000.0 -0.55 585240.0 15200.0 0.04 -0.3594 -0.6516 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A15 compound treatment 578510.0 -79300.0 -0.21 482370.0 -87700.0 -0.24 -0.32 -0.998 3175963 PK04_100013 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A16 compound treatment 544480.0 -113000.0 -0.3 382240.0 -188000.0 -0.52 -0.5786 -0.9678 3052785 PK04_100014 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A17 compound treatment 460080.0 -198000.0 -0.53 683530.0 113000.0 0.31 -0.1531 -0.2498 3052837 PK04_100015 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A18 compound treatment 446480.0 -211000.0 -0.56 563700.0 -6350.0 -0.02 -0.4114 -0.7286 3176262 PK04_100016 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A19 compound treatment 606300.0 -51500.0 -0.14 807450.0 237000.0 0.65 0.3636 0.5458 3176686 PK04_100017 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A20 compound treatment 500960.0 -157000.0 -0.42 383890.0 -186000.0 -0.51 -0.6576 -0.9951 3176371 PK04_100018 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A21 compound treatment 544180.0 -114000.0 -0.3 412480.0 -158000.0 -0.43 -0.5205 -0.985 3052829 PK04_100019 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A22 compound treatment 754520.0 96700.0 0.26 690560.0 121000.0 0.33 0.4166 0.9925 3052833 PK04_100020 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A23 compound treatment 444570.0 -213000.0 -0.57 605450.0 35400.0 0.1 -0.334 -0.5781 3052878 PK04_100021 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 A24 compound treatment 374150.0 -284000.0 -0.76 458430.0 -112000.0 -0.31 -0.7524 -0.9207 3052694 PK04_100022 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B01 compound treatment 830350.0 173000.0 0.46 343070.0 -227000.0 -0.62 -0.1148 -0.1481 3052928 PK04_100023 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B02 compound treatment 743580.0 85800.0 0.23 444480.0 -126000.0 -0.34 -0.0818 -0.1975 3052800 PK04_100024 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B03 compound treatment 275970.0 -382000.0 -1.02 718610.0 149000.0 0.41 -0.4328 -0.394 3052842 PK04_100025 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B04 compound treatment 753020.0 95200.0 0.25 819250.0 249000.0 0.68 0.6636 0.9092 3176782 PK04_100026 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B05 compound treatment 921250.0 263000.0 0.7 272380.0 -298000.0 -0.82 -0.0803 -0.0745 3175971 PK04_100027 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B06 compound treatment 480980.0 -177000.0 -0.47 625680.0 55600.0 0.15 -0.226 -0.4552 3176561 PK04_100028 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B07 compound treatment 267430.0 -390000.0 -1.04 329760.0 -240000.0 -0.66 -1.2038 -0.9756 3176369 PK04_100029 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B08 compound treatment 853840.0 196000.0 0.52 819150.0 249000.0 0.68 0.8538 0.9913 3176441 PK04_100030 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B09 compound treatment 445300.0 -212000.0 -0.57 612640.0 42600.0 0.12 -0.3187 -0.5499 3052641 PK04_100031 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B10 compound treatment 758320.0 101000.0 0.27 449280.0 -121000.0 -0.33 -0.0446 -0.1046 3176555 PK04_100032 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B11 compound treatment 532330.0 -125000.0 -0.34 434400.0 -136000.0 -0.37 -0.5003 -0.9986 3176554 PK04_100033 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B12 compound treatment 467080.0 -191000.0 -0.51 298310.0 -272000.0 -0.75 -0.8877 -0.9827 3052747 PK04_100034 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B13 mock treatment 835680.0 178000.0 0.48 303270.0 -267000.0 -0.73 -0.182 -0.2084 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B14 mock treatment 699170.0 41400.0 0.11 644280.0 74200.0 0.2 0.2222 0.9587 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B15 compound treatment 397760.0 -260000.0 -0.69 377520.0 -193000.0 -0.53 -0.8649 -0.9909 3052707 PK04_100035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B16 compound treatment 419310.0 -238000.0 -0.64 496370.0 -73700.0 -0.2 -0.5935 -0.888 3176447 PK04_100036 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B17 compound treatment 574880.0 -82900.0 -0.22 510820.0 -59200.0 -0.16 -0.2716 -0.9885 3176194 PK04_100037 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B18 compound treatment 378170.0 -280000.0 -0.75 579740.0 9690.0 0.03 -0.5093 -0.6815 3176504 PK04_100038 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B19 compound treatment 453160.0 -205000.0 -0.55 597330.0 27300.0 0.07 -0.3335 -0.6046 3176439 PK04_100039 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B20 compound treatment 717630.0 59800.0 0.16 619520.0 49500.0 0.14 0.209 0.9967 3176678 PK04_100040 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B21 compound treatment 451150.0 -207000.0 -0.55 808660.0 239000.0 0.66 0.0729 0.0851 3176260 PK04_100041 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B22 compound treatment 421830.0 -236000.0 -0.63 596130.0 26100.0 0.07 -0.395 -0.6228 3176621 PK04_100042 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B23 compound treatment 651740.0 -6060.0 -0.02 653230.0 83200.0 0.23 0.15 0.6553 3176370 PK04_100043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 B24 compound treatment 668480.0 10700.0 0.03 612090.0 42000.0 0.12 0.1018 0.8561 3176636 PK04_100044 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C01 compound treatment 724810.0 67000.0 0.18 312610.0 -257000.0 -0.71 -0.3732 -0.5119 3052532 PK04_100045 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C02 compound treatment 724760.0 67000.0 0.18 699280.0 129000.0 0.35 0.3773 0.9497 3052638 PK04_100046 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C03 compound treatment 732930.0 75100.0 0.2 741790.0 172000.0 0.47 0.4753 0.9275 3052540 PK04_100047 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C04 compound treatment 351800.0 -306000.0 -0.82 807090.0 237000.0 0.65 -0.1178 -0.1127 3052751 PK04_100048 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C05 compound treatment 772550.0 115000.0 0.31 307490.0 -263000.0 -0.72 -0.293 -0.374 3052702 PK04_100049 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C06 compound treatment 239560.0 -418000.0 -1.12 321930.0 -248000.0 -0.68 -1.2716 -0.9719 3176680 PK04_100050 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C07 compound treatment 295040.0 -363000.0 -0.97 475210.0 -94800.0 -0.26 -0.8693 -0.8664 3052743 PK04_100051 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C08 compound treatment 221070.0 -437000.0 -1.17 363040.0 -207000.0 -0.57 -1.2267 -0.9454 3176043 PK04_100052 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C09 compound treatment 515700.0 -142000.0 -0.38 492010.0 -78000.0 -0.21 -0.4199 -0.9634 3052925 PK04_100053 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C10 compound treatment 350200.0 -308000.0 -0.82 734560.0 165000.0 0.45 -0.2616 -0.279 3176324 PK04_100054 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C11 mock treatment 482120.0 -176000.0 -0.47 363230.0 -207000.0 -0.57 -0.7333 -0.9955 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C12 mock treatment 724530.0 66700.0 0.18 242570.0 -327000.0 -0.9 -0.5097 -0.5561 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C13 compound treatment 555940.0 -102000.0 -0.27 574090.0 4040.0 0.01 -0.1845 -0.6777 3176376 PK04_100055 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C14 compound treatment 464180.0 -194000.0 -0.52 417720.0 -152000.0 -0.42 -0.6614 -0.9945 3176324 PK04_100056 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C15 mock treatment 740810.0 83000.0 0.22 708410.0 138000.0 0.38 0.4254 0.9671 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C16 mock treatment 519360.0 -138000.0 -0.37 403290.0 -167000.0 -0.46 -0.5852 -0.9944 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C17 compound treatment 418430.0 -239000.0 -0.64 422560.0 -147000.0 -0.4 -0.7384 -0.9757 3052884 PK04_100057 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C18 compound treatment 734180.0 76400.0 0.2 427900.0 -142000.0 -0.39 -0.1317 -0.2991 3176562 PK04_100058 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C19 compound treatment 488480.0 -169000.0 -0.45 337620.0 -232000.0 -0.64 -0.771 -0.9858 3176124 PK04_100059 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C20 compound treatment 470330.0 -187000.0 -0.5 394200.0 -176000.0 -0.48 -0.6955 -0.9998 3052784 PK04_100060 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C21 compound treatment 563400.0 -94400.0 -0.25 405760.0 -164000.0 -0.45 -0.4972 -0.9622 3052792 PK04_100061 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C22 compound treatment 433780.0 -224000.0 -0.6 409600.0 -160000.0 -0.44 -0.7346 -0.9887 3052749 PK04_100062 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C23 compound treatment 536480.0 -121000.0 -0.32 391260.0 -179000.0 -0.49 -0.5762 -0.9797 3176204 PK04_100063 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 C24 compound treatment 508350.0 -149000.0 -0.4 390980.0 -179000.0 -0.49 -0.6299 -0.9947 3176041 PK04_100064 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D01 compound treatment 753230.0 95400.0 0.25 781440.0 211000.0 0.58 0.5906 0.9318 3052926 PK04_100065 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D02 compound treatment 839200.0 181000.0 0.48 399200.0 -171000.0 -0.47 0.0109 0.0162 3176201 PK04_100066 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D03 compound treatment 335760.0 -322000.0 -0.86 541520.0 -28500.0 -0.08 -0.6636 -0.7683 3052885 PK04_100067 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D04 compound treatment 509060.0 -149000.0 -0.4 388800.0 -181000.0 -0.5 -0.6328 -0.9938 3176377 PK04_100068 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D05 compound treatment 512520.0 -145000.0 -0.39 638330.0 68300.0 0.19 -0.1418 -0.3291 3052790 PK04_100069 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D06 compound treatment 266680.0 -391000.0 -1.04 835370.0 265000.0 0.73 -0.2236 -0.1756 3052881 PK04_100070 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D07 compound treatment 403650.0 -254000.0 -0.68 489920.0 -80100.0 -0.22 -0.6356 -0.8907 3052536 PK04_100071 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D08 compound treatment 486950.0 -171000.0 -0.46 392570.0 -177000.0 -0.49 -0.6672 -0.9995 3052923 PK04_100072 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D09 compound treatment 418140.0 -240000.0 -0.64 379210.0 -191000.0 -0.52 -0.8231 -0.9951 3052690 PK04_100073 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D10 compound treatment 449220.0 -209000.0 -0.56 243010.0 -327000.0 -0.9 -1.0288 -0.9737 3052841 PK04_100074 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D11 mock treatment 604960.0 -52800.0 -0.14 644330.0 74300.0 0.2 0.0444 0.179 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D12 mock treatment 330140.0 -328000.0 -0.88 417870.0 -152000.0 -0.42 -0.9143 -0.9428 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D13 compound treatment 398420.0 -259000.0 -0.69 595940.0 25900.0 0.07 -0.4396 -0.6313 3176624 PK04_100075 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D14 compound treatment 434480.0 -223000.0 -0.6 467310.0 -103000.0 -0.28 -0.6212 -0.9415 3176375 PK04_100076 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D15 mock treatment 734240.0 76400.0 0.2 587170.0 17100.0 0.05 0.1776 0.8477 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D16 mock treatment 563370.0 -94400.0 -0.25 365380.0 -205000.0 -0.56 -0.5757 -0.9347 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D17 compound treatment 519240.0 -139000.0 -0.37 729610.0 160000.0 0.44 0.0481 0.0838 3176503 PK04_100077 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D18 compound treatment 664060.0 6260.0 0.02 629350.0 59300.0 0.16 0.1269 0.7757 3052543 PK04_100078 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D19 compound treatment 323250.0 -335000.0 -0.89 534880.0 -35200.0 -0.1 -0.7001 -0.779 3052538 PK04_100079 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D20 compound treatment 528490.0 -129000.0 -0.35 664800.0 94700.0 0.26 -0.0603 -0.1394 3052705 PK04_100080 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D21 compound treatment 505870.0 -152000.0 -0.41 398350.0 -172000.0 -0.47 -0.6203 -0.9972 3052691 PK04_100081 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D22 compound treatment 652640.0 -5160.0 -0.01 656020.0 86000.0 0.24 0.1571 0.6647 3052534 PK04_100082 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D23 compound treatment 591860.0 -65900.0 -0.18 529680.0 -40400.0 -0.11 -0.2029 -0.9751 3176202 PK04_100083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 D24 compound treatment 392400.0 -265000.0 -0.71 648750.0 78700.0 0.22 -0.3485 -0.4702 3176197 PK04_100084 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E01 mock treatment 730400.0 72600.0 0.19 736890.0 167000.0 0.46 0.461 0.9268 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E02 mock treatment 584540.0 -73300.0 -0.2 606110.0 36100.0 0.1 -0.0684 -0.3118 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E03 compound treatment 596690.0 -61100.0 -0.16 769530.0 199000.0 0.55 0.2718 0.4757 3176672 PK04_100085 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E04 compound treatment 658630.0 831.0 0.0 316890.0 -253000.0 -0.7 -0.4899 -0.7048 3052883 PK04_100086 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E05 compound treatment 490290.0 -168000.0 -0.45 224980.0 -345000.0 -0.95 -0.9863 -0.9414 3176126 PK04_100087 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E06 compound treatment 579810.0 -78000.0 -0.21 382980.0 -187000.0 -0.51 -0.5105 -0.921 3052533 PK04_100088 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E07 compound treatment 623200.0 -34600.0 -0.09 404920.0 -165000.0 -0.45 -0.3859 -0.8341 3175839 PK04_100089 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E08 compound treatment 712840.0 55000.0 0.15 381090.0 -189000.0 -0.52 -0.2629 -0.4875 3052695 PK04_100090 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E09 mock treatment 919440.0 262000.0 0.7 469760.0 -100000.0 -0.28 0.2995 0.3987 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E10 mock treatment 871010.0 213000.0 0.57 846020.0 276000.0 0.76 0.9384 0.9901 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E11 compound treatment 444390.0 -213000.0 -0.57 502520.0 -67500.0 -0.19 -0.5342 -0.8912 3176568 PK04_100091 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E12 compound treatment 404440.0 -253000.0 -0.68 663360.0 93300.0 0.26 -0.2974 -0.411 3176044 PK04_100092 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E13 compound treatment 436810.0 -221000.0 -0.59 531480.0 -38600.0 -0.11 -0.4923 -0.8209 3052753 PK04_100093 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E14 compound treatment 493350.0 -164000.0 -0.44 414660.0 -155000.0 -0.43 -0.6123 -0.9999 3175962 PK04_100094 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E15 compound treatment 502480.0 -155000.0 -0.41 476530.0 -93500.0 -0.26 -0.4749 -0.9734 3176325 PK04_100095 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E16 compound treatment 600030.0 -57800.0 -0.15 371540.0 -199000.0 -0.55 -0.4945 -0.873 3052542 PK04_100096 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E17 mock treatment 833320.0 176000.0 0.47 341480.0 -229000.0 -0.63 -0.1122 -0.1433 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E18 mock treatment 822150.0 164000.0 0.44 488090.0 -82000.0 -0.23 0.1513 0.3067 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E19 compound treatment 584190.0 -73600.0 -0.2 506470.0 -63600.0 -0.17 -0.2625 -0.9982 3052746 PK04_100097 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E20 compound treatment 490720.0 -167000.0 -0.45 555260.0 -14800.0 -0.04 -0.3443 -0.7683 3176676 PK04_100098 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E21 compound treatment 430890.0 -227000.0 -0.61 464870.0 -105000.0 -0.29 -0.6328 -0.9425 3052756 PK04_100099 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E22 compound treatment 531930.0 -126000.0 -0.34 465760.0 -104000.0 -0.29 -0.4402 -0.9968 3176560 PK04_100100 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E23 compound treatment 468520.0 -189000.0 -0.51 381780.0 -188000.0 -0.52 -0.723 -0.9999 3052487 PK04_100101 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 E24 compound treatment 661400.0 3600.0 0.01 333440.0 -237000.0 -0.65 -0.4525 -0.6966 3176563 PK04_100102 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F01 mock treatment 791970.0 134000.0 0.36 459430.0 -111000.0 -0.3 0.0386 0.0823 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F02 mock treatment 289230.0 -369000.0 -0.98 865080.0 295000.0 0.81 -0.1234 -0.0968 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F03 compound treatment 481550.0 -176000.0 -0.47 268380.0 -302000.0 -0.83 -0.9185 -0.9642 3176684 PK04_100103 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F04 compound treatment 382260.0 -276000.0 -0.74 681220.0 111000.0 0.31 -0.3046 -0.3823 3176121 PK04_100104 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F05 compound treatment 312800.0 -345000.0 -0.92 436000.0 -134000.0 -0.37 -0.9118 -0.9189 3176435 PK04_100105 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F06 compound treatment 385980.0 -272000.0 -0.73 707720.0 138000.0 0.38 -0.2461 -0.3007 3176627 PK04_100106 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F07 compound treatment 411890.0 -246000.0 -0.66 430280.0 -140000.0 -0.38 -0.7358 -0.9672 3176774 PK04_100107 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F08 compound treatment 541440.0 -116000.0 -0.31 370900.0 -199000.0 -0.55 -0.6064 -0.9642 3174822 PK04_100108 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F09 mock treatment 699690.0 41900.0 0.11 452810.0 -117000.0 -0.32 -0.1485 -0.4357 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F10 mock treatment 404270.0 -254000.0 -0.68 491850.0 -78200.0 -0.21 -0.6307 -0.8877 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F11 compound treatment 214910.0 -443000.0 -1.18 283650.0 -286000.0 -0.79 -1.3925 -0.9803 3176192 PK04_100109 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F12 compound treatment 784000.0 126000.0 0.34 275520.0 -295000.0 -0.81 -0.3334 -0.3806 3052594 PK04_100110 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F13 compound treatment 362280.0 -296000.0 -0.79 381160.0 -189000.0 -0.52 -0.9248 -0.9792 3052748 PK04_100111 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F14 compound treatment 588500.0 -69300.0 -0.19 572710.0 2660.0 0.01 -0.1257 -0.6787 3176567 PK04_100112 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F15 compound treatment 479320.0 -178000.0 -0.48 609730.0 39700.0 0.11 -0.2601 -0.5318 3052759 PK04_100113 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F16 compound treatment 578270.0 -79500.0 -0.21 475880.0 -94200.0 -0.26 -0.333 -0.9952 3176780 PK04_100114 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F17 mock treatment 451630.0 -206000.0 -0.55 825660.0 256000.0 0.7 0.1068 0.1198 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F18 mock treatment 665450.0 7650.0 0.02 681620.0 112000.0 0.31 0.231 0.7526 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F19 compound treatment 809440.0 152000.0 0.41 732720.0 163000.0 0.45 0.6022 0.9988 3176625 PK04_100115 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F20 compound treatment 617890.0 -39900.0 -0.11 541210.0 -28800.0 -0.08 -0.1314 -0.9893 3052750 PK04_100116 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F21 compound treatment 641020.0 -16800.0 -0.04 443870.0 -126000.0 -0.35 -0.2767 -0.792 3052889 PK04_100117 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F22 compound treatment 629810.0 -28000.0 -0.07 686950.0 117000.0 0.32 0.1741 0.5282 3052696 PK04_100118 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F23 compound treatment 651760.0 -6040.0 -0.02 447450.0 -123000.0 -0.34 -0.2494 -0.7401 3176674 PK04_100119 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 F24 compound treatment 576000.0 -81800.0 -0.22 632060.0 62000.0 0.17 -0.0341 -0.1232 3176436 PK04_100120 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G01 compound treatment 416650.0 -241000.0 -0.64 422010.0 -148000.0 -0.41 -0.7429 -0.9754 3052845 PK04_100121 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G02 compound treatment 401950.0 -256000.0 -0.68 529410.0 -40600.0 -0.11 -0.5621 -0.8118 3052835 PK04_100122 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G03 mock treatment 974470.0 317000.0 0.85 655470.0 85400.0 0.23 0.7639 0.8703 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G04 mock treatment 406010.0 -252000.0 -0.67 263260.0 -307000.0 -0.84 -1.0711 -0.9938 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G05 compound treatment 821470.0 164000.0 0.44 867640.0 298000.0 0.82 0.8868 0.9571 3176502 PK04_100123 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G06 compound treatment 578400.0 -79400.0 -0.21 419680.0 -150000.0 -0.41 -0.4419 -0.9521 3176265 PK04_100124 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G07 compound treatment 379210.0 -279000.0 -0.74 479040.0 -91000.0 -0.25 -0.7029 -0.8954 3052742 PK04_100125 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G08 compound treatment 383000.0 -275000.0 -0.73 387140.0 -183000.0 -0.5 -0.8741 -0.9829 3052639 PK04_100126 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G09 compound treatment 712440.0 54600.0 0.15 733820.0 164000.0 0.45 0.4211 0.8909 3176200 PK04_100127 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G10 compound treatment 795120.0 137000.0 0.37 653020.0 83000.0 0.23 0.4204 0.9737 3052650 PK04_100128 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G11 compound treatment 365680.0 -292000.0 -0.78 783520.0 213000.0 0.59 -0.1373 -0.1407 3176683 PK04_100129 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G12 compound treatment 181200.0 -477000.0 -1.27 830730.0 261000.0 0.72 -0.3941 -0.2699 3176631 PK04_100130 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G13 compound treatment 603460.0 -54300.0 -0.15 782320.0 212000.0 0.58 0.3094 0.5153 3176045 PK04_100131 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G14 compound treatment 819890.0 162000.0 0.43 463880.0 -106000.0 -0.29 0.1 0.1916 3176196 PK04_100132 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G15 compound treatment 410880.0 -247000.0 -0.66 440070.0 -130000.0 -0.36 -0.7187 -0.9584 3176446 PK04_100133 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G16 compound treatment 749970.0 92200.0 0.25 351780.0 -218000.0 -0.6 -0.2497 -0.3854 3052834 PK04_100134 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G17 compound treatment 778680.0 121000.0 0.32 553140.0 -16900.0 -0.05 0.1955 0.5992 3052640 PK04_100135 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G18 compound treatment 593990.0 -63800.0 -0.17 531300.0 -38800.0 -0.11 -0.1957 -0.9743 3176727 PK04_100136 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G19 mock treatment 612660.0 -45100.0 -0.12 556590.0 -13500.0 -0.04 -0.1114 -0.8833 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G20 mock treatment 770510.0 113000.0 0.3 503490.0 -66600.0 -0.18 0.0837 0.2375 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G21 compound treatment 436860.0 -221000.0 -0.59 679780.0 110000.0 0.3 -0.2043 -0.3083 3176272 PK04_100137 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G22 compound treatment 335090.0 -323000.0 -0.86 447200.0 -123000.0 -0.34 -0.848 -0.9162 3176261 PK04_100138 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G23 compound treatment 545080.0 -113000.0 -0.3 463490.0 -107000.0 -0.29 -0.4198 -0.9999 3176513 PK04_100139 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 G24 compound treatment 448380.0 -209000.0 -0.56 489780.0 -80300.0 -0.22 -0.5514 -0.9171 3052924 PK04_100140 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H01 compound treatment 400160.0 -258000.0 -0.69 293210.0 -277000.0 -0.76 -1.024 -0.9988 3176557 PK04_100141 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H02 compound treatment 404450.0 -253000.0 -0.68 371970.0 -198000.0 -0.54 -0.863 -0.9941 3052875 PK04_100142 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H03 mock treatment 622190.0 -35600.0 -0.1 629440.0 59400.0 0.16 0.048 0.2545 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H04 mock treatment 289460.0 -368000.0 -0.98 527040.0 -43000.0 -0.12 -0.7792 -0.7863 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H05 compound treatment 306040.0 -352000.0 -0.94 604360.0 34300.0 0.09 -0.5978 -0.6331 3052652 PK04_100143 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H06 compound treatment 586830.0 -71000.0 -0.19 280570.0 -289000.0 -0.79 -0.696 -0.8519 3052786 PK04_100144 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H07 compound treatment 407450.0 -250000.0 -0.67 557780.0 -12300.0 -0.03 -0.4967 -0.7418 3176328 PK04_100145 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H08 compound treatment 853760.0 196000.0 0.52 207520.0 -363000.0 -1.0 -0.3337 -0.2967 3176321 PK04_100146 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H09 compound treatment 506410.0 -151000.0 -0.4 332570.0 -237000.0 -0.65 -0.747 -0.9736 3176735 PK04_100147 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H10 compound treatment 486250.0 -172000.0 -0.46 262170.0 -308000.0 -0.85 -0.9217 -0.9586 3175969 PK04_100148 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H11 compound treatment 204840.0 -453000.0 -1.21 189200.0 -381000.0 -1.05 -1.5948 -0.9974 3176193 PK04_100149 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H12 compound treatment 697360.0 39600.0 0.11 353890.0 -216000.0 -0.59 -0.3449 -0.5722 3176050 PK04_100150 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H13 compound treatment 667920.0 10100.0 0.03 579220.0 9170.0 0.03 0.0369 0.9994 3176569 PK04_100151 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H14 compound treatment 647640.0 -10200.0 -0.03 671730.0 102000.0 0.28 0.1782 0.6354 3052874 PK04_100152 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H15 compound treatment 821300.0 164000.0 0.44 610660.0 40600.0 0.11 0.3876 0.86 3052832 PK04_100153 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H16 compound treatment 633710.0 -24100.0 -0.06 510120.0 -59900.0 -0.16 -0.1618 -0.9161 3176267 PK04_100154 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H17 compound treatment 491140.0 -167000.0 -0.45 650340.0 80300.0 0.22 -0.1589 -0.3199 3176378 PK04_100155 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H18 compound treatment 761080.0 103000.0 0.28 847220.0 277000.0 0.76 0.7331 0.9058 3176322 PK04_100156 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H19 mock treatment 689410.0 31600.0 0.08 732450.0 162000.0 0.45 0.375 0.8263 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H20 mock treatment 575370.0 -82400.0 -0.22 457460.0 -113000.0 -0.31 -0.3743 -0.9862 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H21 compound treatment 609540.0 -48300.0 -0.13 556000.0 -14100.0 -0.04 -0.1184 -0.8802 3052801 PK04_100157 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H22 compound treatment 729050.0 71300.0 0.19 472450.0 -97600.0 -0.27 -0.0549 -0.1671 3176726 PK04_100158 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H23 compound treatment 605140.0 -52700.0 -0.14 747390.0 177000.0 0.49 0.2448 0.4831 3176558 PK04_100159 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 H24 compound treatment 502640.0 -155000.0 -0.41 672600.0 103000.0 0.28 -0.094 -0.1876 3052704 PK04_100160 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I01 compound treatment 902570.0 245000.0 0.65 813780.0 244000.0 0.67 0.9354 0.9999 3052648 PK04_100161 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I02 compound treatment 869060.0 211000.0 0.56 474590.0 -95500.0 -0.26 0.2137 0.3434 3176506 PK04_100162 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I03 compound treatment 773180.0 115000.0 0.31 361780.0 -208000.0 -0.57 -0.1864 -0.287 3176274 PK04_100163 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I04 compound treatment 234100.0 -424000.0 -1.13 316130.0 -254000.0 -0.7 -1.2932 -0.9729 3176679 PK04_100164 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I05 mock treatment 344800.0 -313000.0 -0.84 278240.0 -292000.0 -0.8 -1.1577 -0.9998 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I06 mock treatment 372880.0 -285000.0 -0.76 458790.0 -111000.0 -0.31 -0.7541 -0.9196 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I07 compound treatment 411950.0 -246000.0 -0.66 523650.0 -46400.0 -0.13 -0.5544 -0.8288 3052930 PK04_100165 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I08 compound treatment 568910.0 -88900.0 -0.24 476570.0 -93500.0 -0.26 -0.3494 -0.9992 3176444 PK04_100166 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I09 compound treatment 660880.0 3080.0 0.01 478350.0 -91700.0 -0.25 -0.1722 -0.6836 3052697 PK04_100167 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I10 compound treatment 536350.0 -121000.0 -0.32 587750.0 17700.0 0.05 -0.195 -0.5946 3176731 PK04_100168 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I11 compound treatment 382440.0 -275000.0 -0.74 452180.0 -118000.0 -0.32 -0.7489 -0.932 3052535 PK04_100169 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I12 compound treatment 735590.0 77800.0 0.21 295160.0 -275000.0 -0.75 -0.3867 -0.4941 3176198 PK04_100170 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I13 compound treatment 711710.0 53900.0 0.14 739360.0 169000.0 0.46 0.4305 0.8847 3176119 PK04_100171 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I14 compound treatment 856040.0 198000.0 0.53 702080.0 132000.0 0.36 0.6307 0.9829 3176442 PK04_100172 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I15 compound treatment 743320.0 85500.0 0.23 741770.0 172000.0 0.47 0.4949 0.9447 3176566 PK04_100173 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I16 compound treatment 758320.0 101000.0 0.27 591520.0 21500.0 0.06 0.2315 0.8423 3052844 PK04_100174 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I17 compound treatment 678270.0 20500.0 0.05 601150.0 31100.0 0.09 0.099 0.9768 3176781 PK04_100175 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I18 compound treatment 616800.0 -41000.0 -0.11 862880.0 293000.0 0.8 0.491 0.6052 3052891 PK04_100176 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I19 compound treatment 615060.0 -42700.0 -0.11 435360.0 -135000.0 -0.37 -0.3422 -0.8842 3052840 PK04_100177 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I20 compound treatment 604830.0 -53000.0 -0.14 609950.0 39900.0 0.11 -0.0226 -0.1263 3174821 PK04_100178 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I21 mock treatment 668820.0 11000.0 0.03 524280.0 -45800.0 -0.13 -0.068 -0.5272 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I22 mock treatment 571550.0 -86200.0 -0.23 779450.0 209000.0 0.57 0.2436 0.3933 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I23 compound treatment 496500.0 -161000.0 -0.43 577030.0 6980.0 0.02 -0.2911 -0.675 3176670 PK04_100179 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 I24 compound treatment 500240.0 -158000.0 -0.42 562490.0 -7560.0 -0.02 -0.3123 -0.7411 3176728 PK04_100180 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J01 compound treatment 580600.0 -77200.0 -0.21 517120.0 -52900.0 -0.15 -0.2486 -0.9853 3176783 PK04_100181 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J02 compound treatment 566340.0 -91500.0 -0.24 526730.0 -43300.0 -0.12 -0.2568 -0.9453 3176448 PK04_100182 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J03 compound treatment 469610.0 -188000.0 -0.5 344710.0 -225000.0 -0.62 -0.7929 -0.9947 3176047 PK04_100183 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J04 compound treatment 588000.0 -69800.0 -0.19 411110.0 -159000.0 -0.44 -0.4404 -0.9281 3176269 PK04_100184 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J05 mock treatment 383330.0 -274000.0 -0.73 256430.0 -314000.0 -0.86 -1.1272 -0.9968 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J06 mock treatment 562880.0 -94900.0 -0.25 481450.0 -88600.0 -0.24 -0.3513 -0.9998 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J07 compound treatment 554200.0 -104000.0 -0.28 691850.0 122000.0 0.33 0.0408 0.094 3176635 PK04_100185 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J08 compound treatment 620900.0 -36900.0 -0.1 733340.0 163000.0 0.45 0.2473 0.5388 3176114 PK04_100186 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J09 compound treatment 687850.0 30100.0 0.08 429930.0 -140000.0 -0.38 -0.2153 -0.5478 3175966 PK04_100187 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J10 compound treatment 325160.0 -333000.0 -0.89 804610.0 235000.0 0.64 -0.1729 -0.1576 3052757 PK04_100188 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J11 compound treatment 429830.0 -228000.0 -0.61 270040.0 -300000.0 -0.82 -1.013 -0.9889 3174819 PK04_100189 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J12 compound treatment 465050.0 -193000.0 -0.51 397600.0 -172000.0 -0.47 -0.6988 -0.9991 3176738 PK04_100190 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J13 compound treatment 891770.0 234000.0 0.62 796410.0 226000.0 0.62 0.8813 1.0 3176380 PK04_100191 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J14 compound treatment 800800.0 143000.0 0.38 550180.0 -19900.0 -0.05 0.2315 0.6 3176199 PK04_100192 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J15 compound treatment 712130.0 54300.0 0.15 643040.0 73000.0 0.2 0.2443 0.9874 3176623 PK04_100193 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J16 compound treatment 885280.0 227000.0 0.61 623200.0 53100.0 0.15 0.5328 0.8527 3176632 PK04_100194 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J17 compound treatment 667800.0 10000.0 0.03 525480.0 -44600.0 -0.12 -0.0676 -0.54 3052795 PK04_100195 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J18 compound treatment 733370.0 75600.0 0.2 493380.0 -76700.0 -0.21 -0.0061 -0.021 3052636 PK04_100196 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J19 compound treatment 639920.0 -17900.0 -0.05 681950.0 112000.0 0.31 0.1835 0.5901 3052591 PK04_100197 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J20 compound treatment 667250.0 9450.0 0.03 672820.0 103000.0 0.28 0.2173 0.7673 3176629 PK04_100198 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J21 mock treatment 484250.0 -174000.0 -0.46 473140.0 -96900.0 -0.27 -0.5159 -0.9653 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J22 mock treatment 575930.0 -81900.0 -0.22 636500.0 66400.0 0.18 -0.0256 -0.09 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J23 compound treatment 595050.0 -62700.0 -0.17 377180.0 -193000.0 -0.53 -0.4929 -0.8875 3176776 PK04_100199 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 J24 compound treatment 612320.0 -45500.0 -0.12 560670.0 -9380.0 -0.03 -0.1041 -0.8384 3052544 PK04_100200 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K01 compound treatment 1017670.0 360000.0 0.96 963880.0 394000.0 1.08 1.4442 0.9983 3176739 PK04_100201 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K02 compound treatment 728680.0 70900.0 0.19 842000.0 272000.0 0.75 0.6618 0.8592 3176042 PK04_100202 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K03 compound treatment 653780.0 -4020.0 -0.01 855040.0 285000.0 0.78 0.5457 0.6973 3052528 PK04_100203 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K04 compound treatment 809980.0 152000.0 0.41 459710.0 -110000.0 -0.3 0.0732 0.1444 3176564 PK04_100204 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K05 compound treatment 606580.0 -51200.0 -0.14 412430.0 -158000.0 -0.43 -0.4027 -0.8874 3176329 PK04_100205 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K06 compound treatment 900070.0 242000.0 0.65 642110.0 72100.0 0.2 0.5975 0.8829 3052588 PK04_100206 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K07 mock treatment 704180.0 46400.0 0.12 626330.0 56300.0 0.15 0.1968 0.994 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K08 mock treatment 376530.0 -281000.0 -0.75 562730.0 -7320.0 -0.02 -0.5454 -0.7258 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K09 compound treatment 563090.0 -94700.0 -0.25 568320.0 -1730.0 0.0 -0.1822 -0.7203 3176733 PK04_100207 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K10 compound treatment 626780.0 -31000.0 -0.08 520480.0 -49600.0 -0.14 -0.1548 -0.9717 3052589 PK04_100208 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K11 compound treatment 674880.0 17100.0 0.05 646520.0 76500.0 0.21 0.1807 0.8411 3052651 PK04_100209 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K12 compound treatment 595080.0 -62700.0 -0.17 514470.0 -55600.0 -0.15 -0.2264 -0.9989 3176507 PK04_100210 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K13 compound treatment 711400.0 53600.0 0.14 679250.0 109000.0 0.3 0.3132 0.9428 3052706 PK04_100211 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K14 compound treatment 707450.0 49700.0 0.13 946810.0 377000.0 1.03 0.8252 0.7913 3175959 PK04_100212 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K15 mock treatment 709800.0 52000.0 0.14 744920.0 175000.0 0.48 0.4377 0.8758 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K16 mock treatment 920360.0 263000.0 0.7 701840.0 132000.0 0.36 0.7517 0.9526 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K17 compound treatment 729840.0 72000.0 0.19 669960.0 99900.0 0.27 0.33 0.985 3174817 PK04_100213 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K18 compound treatment 641620.0 -16200.0 -0.04 737690.0 168000.0 0.46 0.2949 0.6379 3176725 PK04_100214 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K19 compound treatment 604100.0 -53700.0 -0.14 721360.0 151000.0 0.42 0.1923 0.4376 3052537 PK04_100215 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K20 compound treatment 541490.0 -116000.0 -0.31 553010.0 -17000.0 -0.05 -0.2528 -0.8045 3052596 PK04_100216 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K21 compound treatment 904160.0 246000.0 0.66 545690.0 -24400.0 -0.07 0.418 0.632 3176049 PK04_100217 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K22 compound treatment 710920.0 53100.0 0.14 459610.0 -110000.0 -0.3 -0.1141 -0.3408 3052637 PK04_100218 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K23 mock treatment 649310.0 -8490.0 -0.02 838780.0 269000.0 0.74 0.5056 0.6851 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 K24 mock treatment 847100.0 189000.0 0.51 641780.0 71700.0 0.2 0.4968 0.9155 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L01 compound treatment 753650.0 95900.0 0.26 551770.0 -18300.0 -0.05 0.1455 0.5578 3052595 PK04_100219 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L02 compound treatment 625160.0 -32600.0 -0.09 682260.0 112000.0 0.31 0.1562 0.4878 3176046 PK04_100220 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L03 compound treatment 379150.0 -279000.0 -0.74 409200.0 -161000.0 -0.44 -0.8385 -0.9689 3052585 PK04_100221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L04 compound treatment 399210.0 -259000.0 -0.69 408130.0 -162000.0 -0.44 -0.8027 -0.9773 3176734 PK04_100222 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L05 compound treatment 848040.0 190000.0 0.51 700810.0 131000.0 0.36 0.6131 0.9855 3176688 PK04_100223 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L06 compound treatment 380120.0 -278000.0 -0.74 636020.0 66000.0 0.18 -0.3964 -0.5192 3176372 PK04_100224 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L07 mock treatment 760340.0 103000.0 0.27 335520.0 -235000.0 -0.64 -0.2616 -0.3739 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L08 mock treatment 886930.0 229000.0 0.61 709190.0 139000.0 0.38 0.7029 0.9743 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L09 compound treatment 687570.0 29800.0 0.08 472770.0 -97300.0 -0.27 -0.1326 -0.4759 3176559 PK04_100225 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L10 compound treatment 408850.0 -249000.0 -0.66 557820.0 -12200.0 -0.03 -0.4939 -0.7419 3052527 PK04_100226 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L11 compound treatment 668490.0 10700.0 0.03 409990.0 -160000.0 -0.44 -0.2905 -0.6598 3176432 PK04_100227 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L12 compound treatment 518610.0 -139000.0 -0.37 496740.0 -73300.0 -0.2 -0.4052 -0.9585 3176326 PK04_100228 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L13 compound treatment 733150.0 75400.0 0.2 555090.0 -15000.0 -0.04 0.1133 0.5514 3176737 PK04_100229 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L14 compound treatment 724640.0 66800.0 0.18 773650.0 204000.0 0.56 0.5215 0.8887 3175964 PK04_100230 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L15 mock treatment 652980.0 -4820.0 -0.01 703780.0 134000.0 0.37 0.2505 0.6819 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L16 mock treatment 813440.0 156000.0 0.42 460270.0 -110000.0 -0.3 0.0808 0.1574 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L17 compound treatment 846260.0 188000.0 0.5 793020.0 223000.0 0.61 0.7888 0.9953 3176787 PK04_100231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L18 compound treatment 822590.0 165000.0 0.44 787730.0 218000.0 0.6 0.7338 0.9887 3175960 PK04_100232 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L19 compound treatment 573030.0 -84800.0 -0.23 752240.0 182000.0 0.5 0.1936 0.3526 3176273 PK04_100233 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L20 compound treatment 685060.0 27300.0 0.07 579800.0 9750.0 0.03 0.0704 0.9076 3052882 PK04_100234 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L21 compound treatment 718420.0 60600.0 0.16 671590.0 102000.0 0.28 0.3116 0.9666 3176053 PK04_100235 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L22 compound treatment 718240.0 60400.0 0.16 644540.0 74500.0 0.2 0.2588 0.9931 3052696 PK04_100236 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L23 mock treatment 764210.0 106000.0 0.28 559200.0 -10900.0 -0.03 0.1799 0.6295 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 L24 mock treatment 806740.0 149000.0 0.4 665940.0 95900.0 0.26 0.4674 0.9799 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M01 compound treatment 468320.0 -189000.0 -0.51 640030.0 70000.0 0.19 -0.222 -0.4101 3176052 PK04_100237 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M02 compound treatment 863110.0 205000.0 0.55 498940.0 -71100.0 -0.2 0.2497 0.429 3176323 PK04_100238 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M03 compound treatment 777830.0 120000.0 0.32 887200.0 317000.0 0.87 0.8424 0.9079 3176206 PK04_100239 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M04 compound treatment 745010.0 87200.0 0.23 649450.0 79400.0 0.22 0.3188 0.9994 3052883 PK04_100240 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M05 compound treatment 414580.0 -243000.0 -0.65 401970.0 -168000.0 -0.46 -0.7857 -0.986 3052744 PK04_100241 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M06 compound treatment 807770.0 150000.0 0.4 699750.0 130000.0 0.36 0.535 0.9983 3176505 PK04_100242 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M07 compound treatment 581290.0 -76500.0 -0.2 567740.0 -2310.0 -0.01 -0.149 -0.7287 3176434 PK04_100243 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M08 compound treatment 614440.0 -43400.0 -0.12 621840.0 51800.0 0.14 0.0186 0.1017 3176729 PK04_100244 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M09 mock treatment 765670.0 108000.0 0.29 455240.0 -115000.0 -0.32 -0.0192 -0.0449 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M10 mock treatment 840600.0 183000.0 0.49 878090.0 308000.0 0.85 0.9432 0.9659 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M11 compound treatment 490210.0 -168000.0 -0.45 522350.0 -47700.0 -0.13 -0.4091 -0.8772 3052590 PK04_100245 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M12 compound treatment 783370.0 126000.0 0.34 608720.0 38700.0 0.11 0.3122 0.8875 3176565 PK04_100246 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M13 mock treatment 889080.0 231000.0 0.62 684210.0 114000.0 0.31 0.6584 0.9505 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M14 mock treatment 908210.0 250000.0 0.67 596980.0 26900.0 0.07 0.5252 0.7805 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M15 compound treatment 674880.0 17100.0 0.05 720120.0 150000.0 0.41 0.3236 0.7806 3176508 PK04_100247 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M16 compound treatment 768930.0 111000.0 0.3 611270.0 41200.0 0.11 0.2899 0.9126 3052587 PK04_100248 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M17 compound treatment 986100.0 328000.0 0.88 713930.0 144000.0 0.39 0.8994 0.9351 3052643 PK04_100249 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M18 compound treatment 823270.0 165000.0 0.44 731850.0 162000.0 0.44 0.6266 1.0 3176777 PK04_100250 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M19 compound treatment 618080.0 -39700.0 -0.11 589120.0 19100.0 0.05 -0.038 -0.3213 3052583 PK04_100251 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M20 compound treatment 737920.0 80100.0 0.21 790150.0 220000.0 0.6 0.5786 0.9026 3052586 PK04_100252 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M21 compound treatment 789510.0 132000.0 0.35 529600.0 -40500.0 -0.11 0.1702 0.4614 3052593 PK04_100253 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M22 compound treatment 568660.0 -89100.0 -0.24 694560.0 125000.0 0.34 0.0733 0.1761 3176374 PK04_100254 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M23 compound treatment 760480.0 103000.0 0.27 476280.0 -93800.0 -0.26 0.0119 0.0316 3052699 PK04_100255 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 M24 compound treatment 723200.0 65400.0 0.17 681280.0 111000.0 0.31 0.3394 0.9649 3176628 PK04_100256 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N01 compound treatment 606650.0 -51100.0 -0.14 653780.0 83700.0 0.23 0.0659 0.2466 3052530 PK04_100257 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N02 compound treatment 645390.0 -12400.0 -0.03 757800.0 188000.0 0.52 0.341 0.6603 3176510 PK04_100258 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N03 compound treatment 700830.0 43000.0 0.11 627260.0 57200.0 0.16 0.1923 0.9882 3052646 PK04_100259 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N04 compound treatment 531690.0 -126000.0 -0.34 871780.0 302000.0 0.83 0.3476 0.3887 3176040 PK04_100260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N05 compound treatment 784690.0 127000.0 0.34 680480.0 110000.0 0.3 0.454 0.9985 3052838 PK04_100261 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N06 compound treatment 906290.0 248000.0 0.66 715050.0 145000.0 0.4 0.7508 0.9701 3176263 PK04_100262 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N07 compound treatment 736520.0 78700.0 0.21 705020.0 135000.0 0.37 0.4107 0.964 3176511 PK04_100263 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N08 compound treatment 593870.0 -63900.0 -0.17 740690.0 171000.0 0.47 0.2105 0.4222 3052644 PK04_100264 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N09 mock treatment 865290.0 207000.0 0.55 668820.0 98800.0 0.27 0.5836 0.9459 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N10 mock treatment 828880.0 171000.0 0.46 865980.0 296000.0 0.81 0.8976 0.963 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N11 compound treatment 841800.0 184000.0 0.49 486510.0 -83500.0 -0.23 0.1853 0.3417 3052880 PK04_100265 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N12 compound treatment 477300.0 -180000.0 -0.48 402580.0 -167000.0 -0.46 -0.666 -0.9997 3176732 PK04_100266 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N13 mock treatment 842280.0 184000.0 0.49 624000.0 53900.0 0.15 0.4531 0.8807 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N14 mock treatment 824480.0 167000.0 0.45 629170.0 59100.0 0.16 0.4296 0.9065 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N15 compound treatment 871240.0 213000.0 0.57 639770.0 69700.0 0.19 0.5385 0.8954 3052703 PK04_100267 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N16 compound treatment 649650.0 -8150.0 -0.02 717610.0 148000.0 0.41 0.2711 0.6681 3176120 PK04_100268 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N17 compound treatment 868540.0 211000.0 0.56 731100.0 161000.0 0.44 0.7107 0.9929 3052843 PK04_100269 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N18 compound treatment 660130.0 2330.0 0.01 626500.0 56400.0 0.15 0.114 0.7349 3176116 PK04_100270 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N19 compound treatment 710200.0 52400.0 0.14 422340.0 -148000.0 -0.41 -0.1878 -0.4377 3176319 PK04_100271 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N20 compound treatment 798720.0 141000.0 0.38 757130.0 187000.0 0.51 0.6293 0.9883 3052797 PK04_100272 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N21 compound treatment 646160.0 -11600.0 -0.03 679300.0 109000.0 0.3 0.1901 0.6304 3052581 PK04_100273 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N22 compound treatment 826340.0 169000.0 0.45 439790.0 -130000.0 -0.36 0.0654 0.1138 3176118 PK04_100274 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N23 compound treatment 857710.0 200000.0 0.53 665770.0 95700.0 0.26 0.5634 0.9467 3176207 PK04_100275 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 N24 compound treatment 838590.0 181000.0 0.48 750740.0 181000.0 0.5 0.6922 0.9999 3176266 PK04_100276 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O01 compound treatment 675800.0 18000.0 0.05 433600.0 -136000.0 -0.37 -0.2309 -0.6113 3176687 PK04_100277 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O02 compound treatment 689930.0 32100.0 0.09 773400.0 203000.0 0.56 0.4554 0.8063 3176323 PK04_100278 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O03 compound treatment 660180.0 2380.0 0.01 425810.0 -144000.0 -0.4 -0.2755 -0.6957 3176438 PK04_100279 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O04 compound treatment 438780.0 -219000.0 -0.58 492320.0 -77700.0 -0.21 -0.5646 -0.9066 3176117 PK04_100280 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O05 compound treatment 653680.0 -4120.0 -0.01 417540.0 -153000.0 -0.42 -0.3039 -0.7254 3176384 PK04_100281 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O06 compound treatment 560960.0 -96800.0 -0.26 513190.0 -56900.0 -0.16 -0.2933 -0.9708 3052695 PK04_100282 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O07 compound treatment 693540.0 35700.0 0.1 835330.0 265000.0 0.73 0.5825 0.793 3052929 PK04_100283 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O08 compound treatment 484870.0 -173000.0 -0.46 768750.0 199000.0 0.55 0.0591 0.0827 3052798 PK04_100284 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O09 compound treatment 485360.0 -172000.0 -0.46 578570.0 8520.0 0.02 -0.3091 -0.6704 3176509 PK04_100285 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O10 compound treatment 780220.0 122000.0 0.33 677440.0 107000.0 0.29 0.4397 0.9987 3176681 PK04_100286 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O11 mock treatment 765410.0 108000.0 0.29 621370.0 51300.0 0.14 0.3029 0.9462 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O12 mock treatment 774830.0 117000.0 0.31 621700.0 51600.0 0.14 0.3213 0.9361 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O13 compound treatment 706080.0 48300.0 0.13 656640.0 86600.0 0.24 0.2593 0.9587 3176682 PK04_100287 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O14 compound treatment 512350.0 -145000.0 -0.39 775580.0 206000.0 0.56 0.1243 0.1814 3176320 PK04_100288 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O15 compound treatment 662360.0 4560.0 0.01 504840.0 -65200.0 -0.18 -0.118 -0.6575 3176268 PK04_100289 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O16 compound treatment 648900.0 -8900.0 -0.02 611360.0 41300.0 0.11 0.0634 0.547 3176373 PK04_100290 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O17 compound treatment 696690.0 38900.0 0.1 529730.0 -40300.0 -0.11 -0.0048 -0.0318 3052700 PK04_100291 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O18 compound treatment 555610.0 -102000.0 -0.27 523300.0 -46800.0 -0.13 -0.2838 -0.9408 3176275 PK04_100292 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O19 compound treatment 542280.0 -116000.0 -0.31 616100.0 46000.0 0.13 -0.1288 -0.3862 3052887 PK04_100293 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O20 compound treatment 506570.0 -151000.0 -0.4 716220.0 146000.0 0.4 -0.0019 -0.0033 3176039 PK04_100294 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O21 compound treatment 790080.0 132000.0 0.35 626030.0 56000.0 0.15 0.3585 0.9305 3176637 PK04_100295 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O22 compound treatment 564640.0 -93200.0 -0.25 534560.0 -35500.0 -0.1 -0.2449 -0.9163 3176115 PK04_100296 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O23 compound treatment 402290.0 -256000.0 -0.68 570260.0 206.0 0.0 -0.4822 -0.7065 3052755 PK04_100297 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 O24 compound treatment 583230.0 -74600.0 -0.2 469870.0 -100000.0 -0.28 -0.3353 -0.9874 3176443 PK04_100298 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P01 compound treatment 455570.0 -202000.0 -0.54 419780.0 -150000.0 -0.41 -0.6737 -0.9912 3052698 PK04_100299 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P02 compound treatment 405730.0 -252000.0 -0.67 602600.0 32500.0 0.09 -0.4129 -0.6079 3176634 PK04_100300 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P03 compound treatment 293760.0 -364000.0 -0.97 361960.0 -208000.0 -0.57 -1.0915 -0.9679 3174820 PK04_100301 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P04 compound treatment 405230.0 -253000.0 -0.67 412570.0 -157000.0 -0.43 -0.7827 -0.9769 3052597 PK04_100302 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P05 compound treatment 336730.0 -321000.0 -0.86 482490.0 -87600.0 -0.24 -0.7764 -0.8717 3176270 PK04_100303 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P06 compound treatment 262490.0 -395000.0 -1.06 452700.0 -117000.0 -0.32 -0.9744 -0.8827 3176677 PK04_100304 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P07 compound treatment 290140.0 -368000.0 -0.98 404430.0 -166000.0 -0.45 -1.0159 -0.9388 3176122 PK04_100305 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P08 compound treatment 385970.0 -272000.0 -0.73 386170.0 -184000.0 -0.5 -0.8704 -0.9842 3052701 PK04_100306 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P09 compound treatment 430650.0 -227000.0 -0.61 426960.0 -143000.0 -0.39 -0.7068 -0.9779 3175972 PK04_100307 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P10 compound treatment 443590.0 -214000.0 -0.57 459080.0 -111000.0 -0.3 -0.62 -0.9565 3052830 PK04_100308 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P11 mock treatment 514880.0 -143000.0 -0.38 391840.0 -178000.0 -0.49 -0.6159 -0.9925 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P12 mock treatment 435090.0 -223000.0 -0.59 402770.0 -167000.0 -0.46 -0.7454 -0.9918 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P13 compound treatment 393480.0 -264000.0 -0.71 363680.0 -206000.0 -0.57 -0.8998 -0.9941 3052541 PK04_100309 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P14 compound treatment 399430.0 -258000.0 -0.69 442110.0 -128000.0 -0.35 -0.7364 -0.9509 3052545 PK04_100310 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P15 compound treatment 644430.0 -13400.0 -0.04 473210.0 -96800.0 -0.27 -0.2133 -0.7949 3176381 PK04_100311 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P16 compound treatment 517800.0 -140000.0 -0.37 436290.0 -134000.0 -0.37 -0.5241 -1.0 3052789 PK04_100312 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P17 compound treatment 461170.0 -197000.0 -0.53 401070.0 -169000.0 -0.46 -0.6994 -0.9981 3052890 PK04_100313 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P18 compound treatment 397950.0 -260000.0 -0.69 465040.0 -105000.0 -0.29 -0.6946 -0.9243 3176779 PK04_100314 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P19 compound treatment 422730.0 -235000.0 -0.63 432010.0 -138000.0 -0.38 -0.712 -0.9708 3052876 PK04_100315 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P20 compound treatment 449850.0 -208000.0 -0.56 441280.0 -129000.0 -0.35 -0.6427 -0.9762 3176264 PK04_100316 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P21 compound treatment 335840.0 -322000.0 -0.86 506690.0 -63400.0 -0.17 -0.7311 -0.8333 3052692 PK04_100317 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P22 compound treatment 378650.0 -279000.0 -0.75 414370.0 -156000.0 -0.43 -0.8295 -0.9651 3176051 PK04_100318 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P23 compound treatment 587940.0 -69900.0 -0.19 540550.0 -29500.0 -0.08 -0.1892 -0.9302 3052754 PK04_100319 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2100 P24 compound treatment 345870.0 -312000.0 -0.83 372010.0 -198000.0 -0.54 -0.9736 -0.9786 3176127 PK04_100320 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A01 compound treatment 355400.0 -289000.0 -0.77 219680.0 -342000.0 -0.94 -1.2103 -0.9953 3189007 PK04_101001 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A02 compound treatment 150500.0 -494000.0 -1.32 568400.0 6810.0 0.02 -0.9203 -0.697 3069619 PK04_101002 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A03 compound treatment 375360.0 -269000.0 -0.72 399210.0 -162000.0 -0.45 -0.8241 -0.9735 3189008 PK04_101003 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A04 compound treatment 685510.0 40700.0 0.11 263790.0 -298000.0 -0.82 -0.5012 -0.6077 3189009 PK04_101004 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A05 compound treatment 151040.0 -494000.0 -1.32 272740.0 -289000.0 -0.79 -1.4933 -0.9704 3069620 PK04_101005 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A06 compound treatment 840820.0 196000.0 0.52 300160.0 -261000.0 -0.72 -0.1373 -0.1545 3189010 PK04_101006 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A07 compound treatment 807560.0 163000.0 0.43 363580.0 -198000.0 -0.54 -0.077 -0.1106 3189011 PK04_101007 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A08 compound treatment 713610.0 68800.0 0.18 281180.0 -280000.0 -0.77 -0.4144 -0.5236 3069621 PK04_101008 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A09 compound treatment 363080.0 -282000.0 -0.75 385710.0 -176000.0 -0.48 -0.8735 -0.977 3189120 PK04_101009 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A10 compound treatment 329170.0 -316000.0 -0.84 329330.0 -232000.0 -0.64 -1.047 -0.9905 3069622 PK04_101010 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A11 compound treatment 433520.0 -211000.0 -0.56 386840.0 -175000.0 -0.48 -0.7383 -0.9967 3189121 PK04_101011 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A12 compound treatment 224660.0 -420000.0 -1.12 353940.0 -208000.0 -0.57 -1.1966 -0.9507 3069678 PK04_101012 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A13 mock treatment 391870.0 -253000.0 -0.68 505320.0 -56300.0 -0.15 -0.5869 -0.8469 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A14 mock treatment 401860.0 -243000.0 -0.65 294020.0 -268000.0 -0.73 -0.9783 -0.9981 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A15 compound treatment 406920.0 -238000.0 -0.64 583790.0 22200.0 0.06 -0.4062 -0.6364 3189122 PK04_101013 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A16 compound treatment 730560.0 85800.0 0.23 786310.0 225000.0 0.62 0.5982 0.909 3069679 PK04_101014 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A17 compound treatment 589300.0 -55500.0 -0.15 352700.0 -209000.0 -0.57 -0.5103 -0.8615 3189123 PK04_101015 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A18 compound treatment 486690.0 -158000.0 -0.42 411420.0 -150000.0 -0.41 -0.5901 -0.9999 3189124 PK04_101016 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A19 compound treatment 555200.0 -89600.0 -0.24 416360.0 -145000.0 -0.4 -0.4511 -0.9702 3069680 PK04_101017 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A20 compound treatment 402800.0 -242000.0 -0.65 630950.0 69400.0 0.19 -0.3224 -0.4785 3189125 PK04_101018 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A21 compound treatment 398890.0 -246000.0 -0.66 629680.0 68100.0 0.19 -0.3322 -0.4865 3069681 PK04_101019 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A22 compound treatment 743520.0 98700.0 0.26 435060.0 -127000.0 -0.35 -0.0592 -0.1357 3189126 PK04_101020 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A23 compound treatment 569860.0 -74900.0 -0.2 511270.0 -50300.0 -0.14 -0.2392 -0.9836 3189127 PK04_101021 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 A24 compound treatment 722080.0 77300.0 0.21 477170.0 -84400.0 -0.23 -0.0179 -0.0577 3069682 PK04_101022 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B01 compound treatment 752800.0 108000.0 0.29 758040.0 196000.0 0.54 0.5854 0.957 3189128 PK04_101023 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B02 compound treatment 772590.0 128000.0 0.34 210690.0 -351000.0 -0.96 -0.4398 -0.4303 3189129 PK04_101024 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B03 compound treatment 873650.0 229000.0 0.61 270780.0 -291000.0 -0.8 -0.1323 -0.1316 3069683 PK04_101025 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B04 compound treatment 842520.0 198000.0 0.53 538440.0 -23200.0 -0.06 0.3285 0.6176 3189130 PK04_101026 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B05 compound treatment 728480.0 83700.0 0.22 745180.0 184000.0 0.5 0.5145 0.9331 3069684 PK04_101027 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B06 compound treatment 696670.0 51900.0 0.14 370460.0 -191000.0 -0.52 -0.2731 -0.5031 3189131 PK04_101028 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B07 compound treatment 410770.0 -234000.0 -0.63 347580.0 -214000.0 -0.59 -0.8574 -0.9995 3189132 PK04_101029 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B08 compound treatment 738340.0 93600.0 0.25 485330.0 -76300.0 -0.21 0.0286 0.0879 3069685 PK04_101030 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B09 compound treatment 592910.0 -51900.0 -0.14 345600.0 -216000.0 -0.59 -0.5173 -0.8495 3189133 PK04_101031 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B10 compound treatment 342290.0 -302000.0 -0.81 530520.0 -31100.0 -0.09 -0.6316 -0.7774 3189129 PK04_101032 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B11 compound treatment 790160.0 145000.0 0.39 461520.0 -100000.0 -0.27 0.0803 0.1688 3189134 PK04_101033 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B12 compound treatment 461920.0 -183000.0 -0.49 606450.0 44900.0 0.12 -0.2583 -0.5128 3069686 PK04_101034 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B13 mock treatment 366080.0 -279000.0 -0.74 716000.0 154000.0 0.42 -0.2266 -0.2646 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B14 mock treatment 800220.0 155000.0 0.42 542210.0 -19400.0 -0.05 0.2559 0.6115 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B15 compound treatment 621800.0 -23000.0 -0.06 384360.0 -177000.0 -0.49 -0.3875 -0.7901 3189135 PK04_101035 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B16 compound treatment 504220.0 -141000.0 -0.38 350830.0 -211000.0 -0.58 -0.6746 -0.9781 3069686 PK04_101036 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B17 compound treatment 524010.0 -121000.0 -0.32 347960.0 -214000.0 -0.59 -0.6428 -0.9604 3189136 PK04_101037 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B18 compound treatment 614240.0 -30500.0 -0.08 640720.0 79100.0 0.22 0.0959 0.4133 3069687 PK04_101038 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B19 compound treatment 534850.0 -110000.0 -0.29 536380.0 -25200.0 -0.07 -0.2566 -0.8505 3189137 PK04_101039 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B20 compound treatment 579460.0 -65300.0 -0.17 808640.0 247000.0 0.68 0.3562 0.5086 3069688 PK04_101040 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B21 compound treatment 613090.0 -31700.0 -0.08 434260.0 -127000.0 -0.35 -0.3071 -0.8537 3189138 PK04_101041 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B22 compound treatment 491380.0 -153000.0 -0.41 539390.0 -22200.0 -0.06 -0.3328 -0.8034 3189139 PK04_101042 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B23 compound treatment 406460.0 -238000.0 -0.64 485680.0 -75900.0 -0.21 -0.5975 -0.892 3069689 PK04_101043 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 B24 compound treatment 637280.0 -7510.0 -0.02 643170.0 81600.0 0.22 0.1442 0.6412 3189140 PK04_101044 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C01 compound treatment 754750.0 110000.0 0.29 469130.0 -92500.0 -0.25 0.0282 0.0726 3189247 PK04_101045 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C02 compound treatment 719130.0 74300.0 0.2 753280.0 192000.0 0.53 0.5125 0.9112 3069724 PK04_101046 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C03 compound treatment 401130.0 -244000.0 -0.65 237280.0 -324000.0 -0.89 -1.0898 -0.9881 3189248 PK04_101047 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C04 compound treatment 779090.0 134000.0 0.36 492080.0 -69500.0 -0.19 0.1187 0.2922 3189249 PK04_101048 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C05 compound treatment 314740.0 -330000.0 -0.88 412160.0 -149000.0 -0.41 -0.9134 -0.9394 3069725 PK04_101049 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C06 compound treatment 662040.0 17300.0 0.05 382990.0 -179000.0 -0.49 -0.3141 -0.6379 3189250 PK04_101050 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C07 compound treatment 420510.0 -224000.0 -0.6 636210.0 74600.0 0.2 -0.2787 -0.4403 3069726 PK04_101051 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C08 compound treatment 712070.0 67300.0 0.18 410560.0 -151000.0 -0.41 -0.1661 -0.3676 3189251 PK04_101052 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C09 compound treatment 559050.0 -85700.0 -0.23 440480.0 -121000.0 -0.33 -0.397 -0.9834 3189252 PK04_101053 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C10 compound treatment 397090.0 -248000.0 -0.66 371630.0 -190000.0 -0.52 -0.8366 -0.9931 3069727 PK04_101054 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C11 mock treatment 541480.0 -103000.0 -0.28 485120.0 -76500.0 -0.21 -0.3436 -0.9909 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C12 mock treatment 629560.0 -15200.0 -0.04 422350.0 -139000.0 -0.38 -0.2991 -0.778 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C13 compound treatment 525560.0 -119000.0 -0.32 684190.0 123000.0 0.34 0.0128 0.0277 3189253 PK04_101055 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C14 compound treatment 585760.0 -59000.0 -0.16 455840.0 -106000.0 -0.29 -0.3168 -0.9588 3069728 PK04_101056 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C15 mock treatment 421160.0 -224000.0 -0.6 409600.0 -152000.0 -0.42 -0.7174 -0.9846 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C16 mock treatment 421490.0 -223000.0 -0.6 651860.0 90300.0 0.25 -0.2465 -0.3817 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C17 compound treatment 501360.0 -143000.0 -0.38 640650.0 79100.0 0.22 -0.1174 -0.2667 3189254 PK04_101057 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C18 compound treatment 442510.0 -202000.0 -0.54 466130.0 -95500.0 -0.26 -0.5674 -0.9448 3189255 PK04_101058 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C19 compound treatment 504410.0 -140000.0 -0.37 467300.0 -94300.0 -0.26 -0.4482 -0.9836 3069729 PK04_101059 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C20 compound treatment 379130.0 -266000.0 -0.71 348080.0 -214000.0 -0.59 -0.9162 -0.9955 3189256 PK04_101060 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C21 compound treatment 464390.0 -180000.0 -0.48 571410.0 9820.0 0.03 -0.3217 -0.6665 3189257 PK04_101061 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C22 compound treatment 472200.0 -173000.0 -0.46 588580.0 27000.0 0.07 -0.2736 -0.5859 3069730 PK04_101062 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C23 compound treatment 453870.0 -191000.0 -0.51 579330.0 17700.0 0.05 -0.3261 -0.6367 3189258 PK04_101063 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 C24 compound treatment 764180.0 119000.0 0.32 528960.0 -32600.0 -0.09 0.1621 0.4895 3069731 PK04_101064 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D01 compound treatment 492760.0 -152000.0 -0.41 333280.0 -228000.0 -0.63 -0.7304 -0.9779 3189259 PK04_101065 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D02 compound treatment 837000.0 192000.0 0.51 284930.0 -277000.0 -0.76 -0.1741 -0.1899 3069687 PK04_101066 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D03 compound treatment 816530.0 172000.0 0.46 483530.0 -78100.0 -0.21 0.1728 0.3413 3189260 PK04_101067 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D04 compound treatment 313920.0 -331000.0 -0.88 637920.0 76300.0 0.21 -0.4767 -0.5249 3069688 PK04_101068 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D05 compound treatment 400520.0 -244000.0 -0.65 761440.0 200000.0 0.55 -0.0734 -0.0861 3069732 PK04_101069 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D06 compound treatment 338560.0 -306000.0 -0.82 598040.0 36500.0 0.1 -0.5076 -0.616 3189139 PK04_101070 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D07 compound treatment 565920.0 -78900.0 -0.21 585700.0 24100.0 0.07 -0.1022 -0.4626 3189261 PK04_101071 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D08 compound treatment 412360.0 -232000.0 -0.62 716400.0 155000.0 0.43 -0.1384 -0.184 3069733 PK04_101072 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D09 compound treatment 730720.0 85900.0 0.23 439480.0 -122000.0 -0.34 -0.0748 -0.184 3189262 PK04_101073 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D10 compound treatment 763250.0 118000.0 0.32 544160.0 -17400.0 -0.05 0.1899 0.5934 3069733 PK04_101074 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D11 mock treatment 697630.0 52800.0 0.14 566930.0 5340.0 0.01 0.1102 0.7764 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D12 mock treatment 637140.0 -7650.0 -0.02 345870.0 -216000.0 -0.59 -0.4332 -0.7311 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D13 compound treatment 535040.0 -110000.0 -0.29 716890.0 155000.0 0.43 0.0942 0.1821 3189263 PK04_101075 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D14 compound treatment 432240.0 -213000.0 -0.57 444180.0 -117000.0 -0.32 -0.6294 -0.964 3069734 PK04_101076 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D15 mock treatment 761280.0 116000.0 0.31 517120.0 -44500.0 -0.12 0.1337 0.4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D16 mock treatment 491600.0 -153000.0 -0.41 443240.0 -118000.0 -0.32 -0.5191 -0.9935 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D17 compound treatment 629240.0 -15500.0 -0.04 632120.0 70500.0 0.19 0.1076 0.5431 3189264 PK04_101077 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D18 compound treatment 458240.0 -187000.0 -0.5 438790.0 -123000.0 -0.34 -0.5907 -0.9819 3069734 PK04_101078 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D19 compound treatment 654680.0 9890.0 0.03 501730.0 -59900.0 -0.16 -0.0975 -0.5859 3069735 PK04_101079 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D20 compound treatment 424100.0 -221000.0 -0.59 649960.0 88400.0 0.24 -0.2453 -0.3848 3189265 PK04_101080 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D21 compound treatment 751300.0 107000.0 0.28 567600.0 6010.0 0.02 0.2128 0.7469 3189266 PK04_101081 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D22 compound treatment 580260.0 -64500.0 -0.17 510830.0 -50800.0 -0.14 -0.2204 -0.9944 3189265 PK04_101082 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D23 compound treatment 658920.0 14100.0 0.04 480480.0 -81100.0 -0.22 -0.1308 -0.579 3069736 PK04_101083 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 D24 compound treatment 583230.0 -61600.0 -0.16 471520.0 -90100.0 -0.25 -0.2911 -0.9803 3189267 PK04_101084 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E01 mock treatment 885880.0 241000.0 0.64 455310.0 -106000.0 -0.29 0.249 0.3522 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E02 mock treatment 737920.0 93100.0 0.25 712060.0 150000.0 0.41 0.468 0.9705 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E03 compound treatment 487280.0 -158000.0 -0.42 694100.0 133000.0 0.36 -0.0402 -0.0724 3189373 PK04_101085 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E04 compound treatment 410100.0 -235000.0 -0.63 734980.0 173000.0 0.48 -0.1066 -0.1355 3189374 PK04_101086 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E05 compound treatment 371690.0 -273000.0 -0.73 314020.0 -248000.0 -0.68 -0.9964 -0.9994 3069761 PK04_101087 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E06 compound treatment 473720.0 -171000.0 -0.46 496580.0 -65000.0 -0.18 -0.4493 -0.9159 3189375 PK04_101088 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E07 compound treatment 754850.0 110000.0 0.29 447750.0 -114000.0 -0.31 -0.0131 -0.0306 3189376 PK04_101089 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E08 compound treatment 677720.0 32900.0 0.09 517640.0 -44000.0 -0.12 -0.0231 -0.1549 3069762 PK04_101090 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E09 mock treatment 428390.0 -216000.0 -0.58 458920.0 -103000.0 -0.28 -0.608 -0.9455 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E10 mock treatment 698330.0 53500.0 0.14 456660.0 -105000.0 -0.29 -0.1026 -0.319 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E11 compound treatment 287900.0 -357000.0 -0.95 504960.0 -56600.0 -0.16 -0.784 -0.8117 3189377 PK04_101091 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E12 compound treatment 362890.0 -282000.0 -0.75 733030.0 171000.0 0.47 -0.1996 -0.2248 3069763 PK04_101092 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E13 compound treatment 607680.0 -37100.0 -0.1 595250.0 33700.0 0.09 -0.0047 -0.035 3189378 PK04_101093 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E14 compound treatment 756000.0 111000.0 0.3 556450.0 -5140.0 -0.01 0.2001 0.6728 3189379 PK04_101094 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E15 compound treatment 755010.0 110000.0 0.29 492910.0 -68700.0 -0.19 0.0748 0.2141 3069764 PK04_101095 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E16 compound treatment 531200.0 -114000.0 -0.3 497720.0 -63900.0 -0.18 -0.3385 -0.966 3189380 PK04_101096 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E17 mock treatment 455230.0 -190000.0 -0.51 592000.0 30400.0 0.08 -0.299 -0.5826 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E18 mock treatment 536760.0 -108000.0 -0.29 555090.0 -6500.0 -0.02 -0.2167 -0.7494 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E19 compound treatment 734570.0 89800.0 0.24 406510.0 -155000.0 -0.43 -0.1315 -0.2691 3069765 PK04_101097 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E20 compound treatment 581410.0 -63400.0 -0.17 569370.0 7780.0 0.02 -0.1046 -0.613 3189381 PK04_101098 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E21 compound treatment 583200.0 -61600.0 -0.16 431870.0 -130000.0 -0.36 -0.3681 -0.9385 3189382 PK04_101099 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E22 compound treatment 501700.0 -143000.0 -0.38 487810.0 -73800.0 -0.2 -0.4135 -0.9559 3069730 PK04_101100 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E23 compound treatment 740530.0 95700.0 0.26 697560.0 136000.0 0.37 0.4448 0.983 3069766 PK04_101101 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 E24 compound treatment 590100.0 -54700.0 -0.15 638520.0 76900.0 0.21 0.0461 0.1793 3069731 PK04_101102 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F01 mock treatment 713800.0 69000.0 0.18 327130.0 -234000.0 -0.64 -0.3248 -0.4851 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F02 mock treatment 858560.0 214000.0 0.57 469390.0 -92200.0 -0.25 0.2248 0.3599 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F03 compound treatment 696070.0 51300.0 0.14 596490.0 34900.0 0.1 0.1646 0.9847 3189383 PK04_101103 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F04 compound treatment 784530.0 140000.0 0.37 313380.0 -248000.0 -0.68 -0.2179 -0.2805 3189267 PK04_101104 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F05 compound treatment 229170.0 -416000.0 -1.11 759710.0 198000.0 0.54 -0.4004 -0.3239 3189384 PK04_101105 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F06 compound treatment 750050.0 105000.0 0.28 239010.0 -323000.0 -0.89 -0.4274 -0.46 3069767 PK04_101106 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F07 compound treatment 456910.0 -188000.0 -0.5 356600.0 -205000.0 -0.56 -0.7528 -0.9984 3189385 PK04_101107 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F08 compound treatment 846010.0 201000.0 0.54 447460.0 -114000.0 -0.31 0.1585 0.2547 3069767 PK04_101108 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F09 mock treatment 795900.0 151000.0 0.4 524060.0 -37500.0 -0.1 0.2125 0.5102 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F10 mock treatment 561120.0 -83700.0 -0.22 725640.0 164000.0 0.45 0.1604 0.3191 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F11 compound treatment 809000.0 164000.0 0.44 335200.0 -226000.0 -0.62 -0.1294 -0.17 3069768 PK04_101109 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F12 compound treatment 647540.0 2750.0 0.01 224760.0 -337000.0 -0.92 -0.6487 -0.7015 3189386 PK04_101110 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F13 compound treatment 740440.0 95700.0 0.26 264740.0 -297000.0 -0.81 -0.3956 -0.4632 3189387 PK04_101111 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F14 compound treatment 838140.0 193000.0 0.52 610270.0 48700.0 0.13 0.4597 0.8617 3189386 PK04_101112 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F15 compound treatment 441180.0 -204000.0 -0.54 827470.0 266000.0 0.73 0.1316 0.1446 3069769 PK04_101113 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F16 compound treatment 470530.0 -174000.0 -0.47 551470.0 -10100.0 -0.03 -0.3488 -0.748 3189388 PK04_101114 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F17 mock treatment 467650.0 -177000.0 -0.47 619570.0 58000.0 0.16 -0.222 -0.4447 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F18 mock treatment 560070.0 -84700.0 -0.23 399840.0 -162000.0 -0.44 -0.474 -0.9511 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F19 compound treatment 389400.0 -255000.0 -0.68 407200.0 -154000.0 -0.42 -0.7821 -0.9738 3189389 PK04_101115 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F20 compound treatment 493730.0 -151000.0 -0.4 558740.0 -2850.0 -0.01 -0.2908 -0.7207 3189388 PK04_101116 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F21 compound treatment 456710.0 -188000.0 -0.5 419360.0 -142000.0 -0.39 -0.6313 -0.9922 3069770 PK04_101117 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F22 compound treatment 601600.0 -43200.0 -0.12 530080.0 -31500.0 -0.09 -0.1427 -0.9899 3189390 PK04_101118 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F23 compound treatment 673920.0 29100.0 0.08 591040.0 29500.0 0.08 0.1122 0.9998 3189391 PK04_101119 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 F24 compound treatment 473520.0 -171000.0 -0.46 730660.0 169000.0 0.46 0.0047 0.0073 3189390 PK04_101120 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G01 compound treatment 513550.0 -131000.0 -0.35 266320.0 -295000.0 -0.81 -0.8211 -0.9297 3189392 PK04_101121 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G02 compound treatment 826040.0 181000.0 0.48 638350.0 76800.0 0.21 0.4913 0.9306 3189374 PK04_101122 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G03 mock treatment 847790.0 203000.0 0.54 515120.0 -46500.0 -0.13 0.2932 0.5264 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G04 mock treatment 357440.0 -287000.0 -0.77 409810.0 -152000.0 -0.42 -0.8374 -0.9588 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G05 compound treatment 425490.0 -219000.0 -0.59 362680.0 -199000.0 -0.55 -0.8003 -0.9994 3069794 PK04_101123 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G06 compound treatment 410880.0 -234000.0 -0.62 239540.0 -322000.0 -0.88 -1.067 -0.9855 3189375 PK04_101124 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G07 compound treatment 569320.0 -75500.0 -0.2 487310.0 -74300.0 -0.2 -0.2867 -1.0 3189393 PK04_101125 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G08 compound treatment 606330.0 -38500.0 -0.1 397970.0 -164000.0 -0.45 -0.3903 -0.8469 3069762 PK04_101126 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G09 compound treatment 434890.0 -210000.0 -0.56 624010.0 62400.0 0.17 -0.2753 -0.4695 3069795 PK04_101127 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G10 compound treatment 468610.0 -176000.0 -0.47 808670.0 247000.0 0.68 0.1469 0.178 3069763 PK04_101128 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G11 compound treatment 349280.0 -296000.0 -0.79 247950.0 -314000.0 -0.86 -1.167 -0.9991 3189504 PK04_101129 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G12 compound treatment 288560.0 -356000.0 -0.95 249490.0 -312000.0 -0.86 -1.2787 -0.9986 3189379 PK04_101130 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G13 compound treatment 586880.0 -57900.0 -0.15 460840.0 -101000.0 -0.28 -0.305 -0.9623 3069796 PK04_101131 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G14 compound treatment 345960.0 -299000.0 -0.8 386830.0 -175000.0 -0.48 -0.9037 -0.9703 3189380 PK04_101132 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G15 compound treatment 521630.0 -123000.0 -0.33 542430.0 -19200.0 -0.05 -0.2698 -0.8099 3189505 PK04_101133 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G16 compound treatment 763840.0 119000.0 0.32 477070.0 -84500.0 -0.23 0.0608 0.1544 3189381 PK04_101134 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G17 compound treatment 537770.0 -107000.0 -0.29 596500.0 34900.0 0.1 -0.1344 -0.4456 3189506 PK04_101135 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G18 compound treatment 663630.0 18800.0 0.05 508800.0 -52800.0 -0.14 -0.0669 -0.4361 3069797 PK04_101136 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G19 mock treatment 759750.0 115000.0 0.31 443970.0 -118000.0 -0.32 -0.0112 -0.0252 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G20 mock treatment 661200.0 16400.0 0.04 565310.0 3720.0 0.01 0.0382 0.8491 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G21 compound treatment 664410.0 19600.0 0.05 428610.0 -133000.0 -0.37 -0.2211 -0.5995 3189507 PK04_101137 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G22 compound treatment 561920.0 -82900.0 -0.22 627000.0 65400.0 0.18 -0.0295 -0.1036 3189508 PK04_101138 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G23 compound treatment 598720.0 -46100.0 -0.12 567380.0 5790.0 0.02 -0.0758 -0.6107 3069798 PK04_101139 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 G24 compound treatment 511910.0 -133000.0 -0.35 772200.0 211000.0 0.58 0.1579 0.2327 3189509 PK04_101140 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H01 compound treatment 805120.0 160000.0 0.43 682110.0 121000.0 0.33 0.5368 0.9919 3069799 PK04_101141 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H02 compound treatment 882820.0 238000.0 0.64 211040.0 -351000.0 -0.96 -0.231 -0.2002 3189510 PK04_101142 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H03 mock treatment 879060.0 234000.0 0.63 351680.0 -210000.0 -0.58 0.035 0.0411 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H04 mock treatment 692330.0 47500.0 0.13 571450.0 9860.0 0.03 0.1089 0.839 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H05 compound treatment 573440.0 -71300.0 -0.19 326740.0 -235000.0 -0.64 -0.5907 -0.8785 3189511 PK04_101143 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H06 compound treatment 417920.0 -227000.0 -0.61 348540.0 -213000.0 -0.58 -0.8421 -0.9998 3069800 PK04_101144 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H07 compound treatment 386450.0 -258000.0 -0.69 414150.0 -147000.0 -0.4 -0.7741 -0.9677 3189512 PK04_101145 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H08 compound treatment 444040.0 -201000.0 -0.54 535940.0 -25700.0 -0.07 -0.4289 -0.7932 3069800 PK04_101146 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H09 compound treatment 523730.0 -121000.0 -0.32 387070.0 -175000.0 -0.48 -0.5674 -0.9817 3189513 PK04_101147 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H10 compound treatment 412070.0 -233000.0 -0.62 758210.0 197000.0 0.54 -0.0578 -0.0702 3189510 PK04_101148 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H11 compound treatment 388290.0 -256000.0 -0.69 240430.0 -321000.0 -0.88 -1.1079 -0.9922 3069801 PK04_101149 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H12 compound treatment 261320.0 -383000.0 -1.02 222890.0 -339000.0 -0.93 -1.3818 -0.9988 3189514 PK04_101150 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H13 compound treatment 438750.0 -206000.0 -0.55 758900.0 197000.0 0.54 -0.0061 -0.0079 3189515 PK04_101151 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H14 compound treatment 960100.0 315000.0 0.84 604290.0 42700.0 0.12 0.6784 0.7978 3189514 PK04_101152 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H15 compound treatment 841180.0 196000.0 0.52 650130.0 88500.0 0.24 0.5428 0.9389 3069802 PK04_101153 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H16 compound treatment 523330.0 -121000.0 -0.32 513280.0 -48300.0 -0.13 -0.3232 -0.9221 3189516 PK04_101154 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H17 compound treatment 661210.0 16400.0 0.04 484060.0 -77500.0 -0.21 -0.1195 -0.5499 3189517 PK04_101155 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H18 compound treatment 890010.0 245000.0 0.65 591040.0 29500.0 0.08 0.5203 0.7884 3189516 PK04_101156 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H19 mock treatment 808760.0 164000.0 0.44 616770.0 55200.0 0.15 0.4168 0.8994 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H20 mock treatment 613370.0 -31400.0 -0.08 488060.0 -73500.0 -0.2 -0.2021 -0.9244 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H21 compound treatment 569120.0 -75700.0 -0.2 335040.0 -227000.0 -0.62 -0.5827 -0.891 3069803 PK04_101157 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H22 compound treatment 814420.0 170000.0 0.45 564320.0 2730.0 0.01 0.3257 0.7187 3189518 PK04_101158 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H23 compound treatment 522120.0 -123000.0 -0.33 650890.0 89300.0 0.25 -0.0583 -0.1425 3069804 PK04_101159 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 H24 compound treatment 552480.0 -92300.0 -0.25 784590.0 223000.0 0.61 0.2586 0.3918 3189518 PK04_101160 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I01 compound treatment 903900.0 259000.0 0.69 393320.0 -168000.0 -0.46 0.1627 0.1955 3189519 PK04_101161 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I02 compound treatment 430290.0 -214000.0 -0.57 429600.0 -132000.0 -0.36 -0.6614 -0.9756 3189520 PK04_101162 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I03 compound treatment 632290.0 -12500.0 -0.03 377680.0 -184000.0 -0.5 -0.3806 -0.7522 3069839 PK04_101163 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I04 compound treatment 826800.0 182000.0 0.49 380390.0 -181000.0 -0.5 -0.008 -0.0115 3189521 PK04_101164 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I05 mock treatment 586820.0 -58000.0 -0.15 572120.0 10500.0 0.03 -0.089 -0.5653 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I06 mock treatment 271110.0 -374000.0 -1.0 380830.0 -181000.0 -0.5 -1.0567 -0.948 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I07 compound treatment 547010.0 -97800.0 -0.26 376110.0 -185000.0 -0.51 -0.5447 -0.9519 3069840 PK04_101165 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I08 compound treatment 376380.0 -268000.0 -0.72 490660.0 -70900.0 -0.19 -0.6446 -0.8677 3189522 PK04_101166 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I09 compound treatment 366730.0 -278000.0 -0.74 300060.0 -262000.0 -0.72 -1.0329 -0.9999 3189523 PK04_101167 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I10 compound treatment 391470.0 -253000.0 -0.68 694240.0 133000.0 0.36 -0.2209 -0.2875 3069841 PK04_101168 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I11 compound treatment 432600.0 -212000.0 -0.57 283260.0 -278000.0 -0.76 -0.9411 -0.9892 3189524 PK04_101169 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I12 compound treatment 488970.0 -156000.0 -0.42 370110.0 -191000.0 -0.53 -0.666 -0.9933 3189640 PK04_101170 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I13 compound treatment 727440.0 82700.0 0.22 540440.0 -21200.0 -0.06 0.115 0.504 3069842 PK04_101171 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I14 compound treatment 746030.0 101000.0 0.27 770020.0 208000.0 0.57 0.5958 0.9414 3189641 PK04_101172 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I15 compound treatment 648500.0 3710.0 0.01 627580.0 66000.0 0.18 0.1351 0.7447 3069843 PK04_101173 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I16 compound treatment 542240.0 -103000.0 -0.27 655920.0 94300.0 0.26 -0.0106 -0.028 3189642 PK04_101174 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I17 compound treatment 823440.0 179000.0 0.48 701490.0 140000.0 0.38 0.609 0.9942 3069844 PK04_101175 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I18 compound treatment 570330.0 -74500.0 -0.2 558250.0 -3340.0 -0.01 -0.1471 -0.7389 3189643 PK04_101176 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I19 compound treatment 728610.0 83800.0 0.22 601930.0 40300.0 0.11 0.2366 0.9473 3069845 PK04_101177 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I20 compound treatment 546610.0 -98200.0 -0.26 633030.0 71400.0 0.2 -0.0467 -0.1427 3189644 PK04_101178 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I21 mock treatment 629050.0 -15700.0 -0.04 655710.0 94100.0 0.26 0.153 0.5844 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I22 mock treatment 543680.0 -101000.0 -0.27 733950.0 172000.0 0.47 0.1436 0.2636 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I23 compound treatment 385780.0 -259000.0 -0.69 400800.0 -161000.0 -0.44 -0.8013 -0.9765 3189645 PK04_101179 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 I24 compound treatment 656590.0 11800.0 0.03 616690.0 55100.0 0.15 0.1293 0.8365 3069846 PK04_101180 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J01 compound treatment 753540.0 109000.0 0.29 664740.0 103000.0 0.28 0.4056 0.9999 3189646 PK04_101181 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J02 compound treatment 906300.0 262000.0 0.7 292480.0 -269000.0 -0.74 -0.0285 -0.028 3189647 PK04_101182 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J03 compound treatment 845280.0 200000.0 0.54 464360.0 -97200.0 -0.27 0.1899 0.3174 3069847 PK04_101183 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J04 compound treatment 653340.0 8550.0 0.02 443790.0 -118000.0 -0.32 -0.2125 -0.6555 3189647 PK04_101184 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J05 mock treatment 459400.0 -185000.0 -0.5 392160.0 -169000.0 -0.47 -0.6791 -0.9995 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J06 mock treatment 552420.0 -92400.0 -0.25 592290.0 30700.0 0.08 -0.1149 -0.4405 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J07 compound treatment 747000.0 102000.0 0.27 582000.0 20400.0 0.06 0.2327 0.8348 3189648 PK04_101185 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J08 compound treatment 533730.0 -111000.0 -0.3 572050.0 10500.0 0.03 -0.1894 -0.6357 3189649 PK04_101186 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J09 compound treatment 696870.0 52100.0 0.14 471680.0 -89900.0 -0.25 -0.0762 -0.2689 3069848 PK04_101187 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J10 compound treatment 618650.0 -26100.0 -0.07 857940.0 296000.0 0.81 0.5259 0.6441 3189649 PK04_101188 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J11 compound treatment 855290.0 211000.0 0.56 318750.0 -243000.0 -0.67 -0.0739 -0.0847 3189650 PK04_101189 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J12 compound treatment 921610.0 277000.0 0.74 359610.0 -202000.0 -0.55 0.1307 0.1414 3189651 PK04_101190 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J13 compound treatment 745200.0 100000.0 0.27 822960.0 261000.0 0.72 0.697 0.9099 3069849 PK04_101191 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J14 compound treatment 908540.0 264000.0 0.7 788000.0 226000.0 0.62 0.9377 0.9981 3189651 PK04_101192 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J15 compound treatment 845480.0 201000.0 0.54 716800.0 155000.0 0.43 0.6803 0.9935 3189652 PK04_101193 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J16 compound treatment 624050.0 -20700.0 -0.06 523920.0 -37700.0 -0.1 -0.1123 -0.9572 3069850 PK04_101194 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J17 compound treatment 576900.0 -67900.0 -0.18 563430.0 1840.0 0.01 -0.1246 -0.6871 3189653 PK04_101195 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J18 compound treatment 625560.0 -19200.0 -0.05 631840.0 70300.0 0.19 0.1001 0.5013 3069850 PK04_101196 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J19 compound treatment 530660.0 -114000.0 -0.3 494610.0 -67000.0 -0.18 -0.3456 -0.9707 3189654 PK04_101197 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J20 compound treatment 734160.0 89400.0 0.24 583480.0 21900.0 0.06 0.2113 0.8583 3069851 PK04_101198 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J21 mock treatment 538820.0 -106000.0 -0.28 666640.0 105000.0 0.29 0.0038 0.0094 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J22 mock treatment 601390.0 -43400.0 -0.12 437440.0 -124000.0 -0.34 -0.323 -0.8971 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J23 compound treatment 700240.0 55500.0 0.15 696930.0 135000.0 0.37 0.3675 0.9187 3189655 PK04_101199 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 J24 compound treatment 653560.0 8770.0 0.02 678630.0 117000.0 0.32 0.2438 0.7566 3069851 PK04_101200 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K01 compound treatment 716510.0 71700.0 0.19 741710.0 180000.0 0.49 0.4851 0.9148 3189656 PK04_101201 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K02 compound treatment 940720.0 296000.0 0.79 853660.0 292000.0 0.8 1.1259 1.0 3189657 PK04_101202 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K03 compound treatment 252800.0 -392000.0 -1.05 710330.0 149000.0 0.41 -0.4516 -0.4018 3069890 PK04_101203 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K04 compound treatment 818240.0 173000.0 0.46 563600.0 2010.0 0.01 0.3315 0.7155 3189658 PK04_101204 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K05 compound treatment 786750.0 142000.0 0.38 565860.0 4270.0 0.01 0.2764 0.7286 3069891 PK04_101205 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K06 compound treatment 758560.0 114000.0 0.3 379550.0 -182000.0 -0.5 -0.1385 -0.2368 3189659 PK04_101206 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K07 mock treatment 530890.0 -114000.0 -0.3 432110.0 -129000.0 -0.36 -0.4665 -0.997 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K08 mock treatment 867290.0 223000.0 0.59 405770.0 -156000.0 -0.43 0.1177 0.1608 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K09 compound treatment 593570.0 -51200.0 -0.14 572490.0 10900.0 0.03 -0.0756 -0.5397 3187684 PK04_101207 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K10 compound treatment 816840.0 172000.0 0.46 357360.0 -204000.0 -0.56 -0.0715 -0.0987 3069892 PK04_101208 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K11 compound treatment 593000.0 -51800.0 -0.14 267750.0 -294000.0 -0.81 -0.6682 -0.8164 3187685 PK04_101209 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K12 compound treatment 560750.0 -84000.0 -0.22 646190.0 84600.0 0.23 0.0055 0.0171 3187686 PK04_101210 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K13 compound treatment 815100.0 170000.0 0.45 633930.0 72300.0 0.2 0.4621 0.931 3069893 PK04_101211 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K14 compound treatment 829650.0 185000.0 0.49 708480.0 147000.0 0.4 0.6343 0.995 3187687 PK04_101212 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K15 mock treatment 808210.0 163000.0 0.44 770900.0 209000.0 0.57 0.715 0.9908 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K16 mock treatment 706850.0 62100.0 0.17 725760.0 164000.0 0.45 0.4359 0.9077 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K17 compound treatment 750790.0 106000.0 0.28 810750.0 249000.0 0.68 0.6839 0.9238 3069894 PK04_101213 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K18 compound treatment 779560.0 135000.0 0.36 621940.0 60400.0 0.17 0.3717 0.938 3187688 PK04_101214 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K19 compound treatment 780070.0 135000.0 0.36 770080.0 208000.0 0.57 0.6602 0.9754 3069895 PK04_101215 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K20 compound treatment 616230.0 -28600.0 -0.08 651300.0 89700.0 0.25 0.1202 0.4662 3187689 PK04_101216 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K21 compound treatment 564690.0 -80100.0 -0.21 748440.0 187000.0 0.51 0.2115 0.3804 3187690 PK04_101217 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K22 compound treatment 600900.0 -43900.0 -0.12 534890.0 -26700.0 -0.07 -0.1347 -0.9744 3069896 PK04_101218 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K23 mock treatment 478560.0 -166000.0 -0.44 598140.0 36600.0 0.1 -0.243 -0.5338 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 K24 mock treatment 674130.0 29300.0 0.08 715900.0 154000.0 0.42 0.355 0.8239 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L01 compound treatment 861530.0 217000.0 0.58 634560.0 73000.0 0.2 0.551 0.8995 3187691 PK04_101219 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L02 compound treatment 932330.0 288000.0 0.77 335930.0 -226000.0 -0.62 0.105 0.1064 3187692 PK04_101220 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L03 compound treatment 605040.0 -39700.0 -0.11 466050.0 -95500.0 -0.26 -0.2605 -0.9208 3069897 PK04_101221 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L04 compound treatment 904590.0 260000.0 0.69 461280.0 -100000.0 -0.28 0.2959 0.3964 3187693 PK04_101222 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L05 compound treatment 760990.0 116000.0 0.31 530050.0 -31500.0 -0.09 0.1582 0.4911 3187694 PK04_101223 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L06 compound treatment 367550.0 -277000.0 -0.74 361370.0 -200000.0 -0.55 -0.9123 -0.9892 3187693 PK04_101224 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L07 mock treatment 661390.0 16600.0 0.04 739770.0 178000.0 0.49 0.3773 0.768 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L08 mock treatment 927080.0 282000.0 0.75 310600.0 -251000.0 -0.69 0.0459 0.0449 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L09 compound treatment 500690.0 -144000.0 -0.38 640730.0 79100.0 0.22 -0.1185 -0.2682 3069898 PK04_101225 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L10 compound treatment 680640.0 35900.0 0.1 547520.0 -14100.0 -0.04 0.0404 0.3912 3187692 PK04_101226 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L11 compound treatment 657940.0 13200.0 0.04 759540.0 198000.0 0.54 0.4091 0.7512 3187695 PK04_101227 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L12 compound treatment 821620.0 177000.0 0.47 546530.0 -15100.0 -0.04 0.3047 0.6427 3187696 PK04_101228 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L13 compound treatment 545210.0 -99600.0 -0.27 526120.0 -35500.0 -0.1 -0.2569 -0.9071 3069899 PK04_101229 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L14 compound treatment 807700.0 163000.0 0.44 627650.0 66100.0 0.18 0.4359 0.9247 3187696 PK04_101230 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L15 mock treatment 636610.0 -8180.0 -0.02 757350.0 196000.0 0.54 0.3646 0.6778 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L16 mock treatment 800560.0 156000.0 0.42 642120.0 80500.0 0.22 0.4505 0.9562 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L17 compound treatment 751920.0 107000.0 0.29 552800.0 -8790.0 -0.02 0.1853 0.6452 3187697 PK04_101231 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L18 compound treatment 831630.0 187000.0 0.5 722510.0 161000.0 0.44 0.6653 0.9982 3187698 PK04_101232 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L19 compound treatment 747680.0 103000.0 0.27 625810.0 64200.0 0.18 0.319 0.977 3069900 PK04_101233 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L20 compound treatment 748230.0 103000.0 0.28 569890.0 8300.0 0.02 0.2115 0.7628 3187698 PK04_101234 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L21 compound treatment 640270.0 -4520.0 -0.01 499380.0 -62200.0 -0.17 -0.1293 -0.7552 3187699 PK04_101235 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L22 compound treatment 831770.0 187000.0 0.5 665160.0 104000.0 0.28 0.5542 0.9643 3187700 PK04_101236 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L23 mock treatment 844670.0 200000.0 0.53 836420.0 275000.0 0.75 0.911 0.9857 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 L24 mock treatment 830010.0 185000.0 0.49 862620.0 301000.0 0.83 0.9342 0.9699 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M01 compound treatment 588480.0 -56300.0 -0.15 547140.0 -14500.0 -0.04 -0.1344 -0.8641 3187701 PK04_101237 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M02 compound treatment 830610.0 186000.0 0.5 613720.0 52100.0 0.14 0.4522 0.8753 3069926 PK04_101238 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M03 compound treatment 798970.0 154000.0 0.41 568110.0 6520.0 0.02 0.3039 0.7371 3187702 PK04_101239 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M04 compound treatment 481040.0 -164000.0 -0.44 397370.0 -164000.0 -0.45 -0.6281 -0.9999 3069927 PK04_101240 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M05 compound treatment 741730.0 96900.0 0.26 488840.0 -72800.0 -0.2 0.0419 0.128 3187703 PK04_101241 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M06 compound treatment 823620.0 179000.0 0.48 385970.0 -176000.0 -0.48 -0.0032 -0.0047 3187824 PK04_101242 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M07 compound treatment 645240.0 450.0 0.0 626080.0 64500.0 0.18 0.126 0.7119 3069928 PK04_101243 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M08 compound treatment 359450.0 -285000.0 -0.76 532960.0 -28600.0 -0.08 -0.5945 -0.7759 3187825 PK04_101244 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M09 mock treatment 522910.0 -122000.0 -0.33 775360.0 214000.0 0.59 0.1848 0.2754 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M10 mock treatment 854110.0 209000.0 0.56 723270.0 162000.0 0.44 0.7092 0.9935 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M11 compound treatment 602270.0 -42500.0 -0.11 649760.0 88200.0 0.24 0.0909 0.3398 3187826 PK04_101245 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M12 compound treatment 697570.0 52800.0 0.14 677020.0 115000.0 0.32 0.3238 0.9335 3069929 PK04_101246 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M13 mock treatment 874850.0 230000.0 0.61 689390.0 128000.0 0.35 0.6826 0.9647 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M14 mock treatment 564600.0 -80200.0 -0.21 759230.0 198000.0 0.54 0.2322 0.3981 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M15 compound treatment 814760.0 170000.0 0.45 590290.0 28700.0 0.08 0.3767 0.8176 3187827 PK04_101247 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M16 compound treatment 859360.0 215000.0 0.57 568010.0 6420.0 0.02 0.4177 0.7285 3187828 PK04_101248 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M17 compound treatment 887860.0 243000.0 0.65 700670.0 139000.0 0.38 0.7291 0.968 3069930 PK04_101249 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M18 compound treatment 778080.0 133000.0 0.36 708020.0 146000.0 0.4 0.536 0.9982 3187829 PK04_101250 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M19 compound treatment 760910.0 116000.0 0.31 714300.0 153000.0 0.42 0.5158 0.989 3069931 PK04_101251 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M20 compound treatment 740590.0 95800.0 0.26 517070.0 -44500.0 -0.12 0.0945 0.3333 3187830 PK04_101252 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M21 compound treatment 743560.0 98800.0 0.26 561020.0 -570.0 0.0 0.1854 0.7029 3187831 PK04_101253 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M22 compound treatment 742760.0 98000.0 0.26 646560.0 85000.0 0.23 0.35 0.9984 3069932 PK04_101254 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M23 compound treatment 817760.0 173000.0 0.46 783070.0 221000.0 0.61 0.7566 0.9908 3187832 PK04_101255 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 M24 compound treatment 744960.0 100000.0 0.27 678830.0 117000.0 0.32 0.4168 0.9958 3187833 PK04_101256 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N01 compound treatment 561280.0 -83500.0 -0.22 730500.0 169000.0 0.46 0.1702 0.3307 3069933 PK04_101257 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N02 compound treatment 903260.0 258000.0 0.69 759060.0 197000.0 0.54 0.8715 0.9928 3187700 PK04_101258 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N03 compound treatment 854720.0 210000.0 0.56 461000.0 -101000.0 -0.28 0.2012 0.3219 3187834 PK04_101259 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N04 compound treatment 813600.0 169000.0 0.45 787680.0 226000.0 0.62 0.7577 0.9877 3069934 PK04_101260 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N05 compound treatment 894790.0 250000.0 0.67 609870.0 48300.0 0.13 0.5659 0.8313 3187835 PK04_101261 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N06 compound treatment 585130.0 -59700.0 -0.16 647840.0 86300.0 0.24 0.0548 0.1919 3069934 PK04_101262 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N07 compound treatment 882560.0 238000.0 0.64 466180.0 -95400.0 -0.26 0.2638 0.3841 3187836 PK04_101263 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N08 compound treatment 817600.0 173000.0 0.46 763880.0 202000.0 0.56 0.7191 0.9958 3069935 PK04_101264 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N09 mock treatment 595450.0 -49300.0 -0.13 752590.0 191000.0 0.52 0.2776 0.5134 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N10 mock treatment 949020.0 304000.0 0.81 714180.0 153000.0 0.42 0.8708 0.9525 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N11 compound treatment 819460.0 175000.0 0.47 600160.0 38600.0 0.11 0.4048 0.8461 3187837 PK04_101265 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N12 compound treatment 873650.0 229000.0 0.61 539900.0 -21700.0 -0.06 0.3901 0.6352 3069935 PK04_101266 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N13 mock treatment 776160.0 131000.0 0.35 645160.0 83600.0 0.23 0.4104 0.9788 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N14 mock treatment 794820.0 150000.0 0.4 756240.0 195000.0 0.53 0.6612 0.9899 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N15 compound treatment 899590.0 255000.0 0.68 701290.0 140000.0 0.38 0.7524 0.9632 3069936 PK04_101267 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N16 compound treatment 890920.0 246000.0 0.66 630920.0 69300.0 0.19 0.5994 0.8759 3187838 PK04_101268 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N17 compound treatment 840480.0 196000.0 0.52 532840.0 -28800.0 -0.08 0.3138 0.5936 3187839 PK04_101269 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N18 compound treatment 848980.0 204000.0 0.55 724640.0 163000.0 0.45 0.7022 0.9952 3187838 PK04_101270 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N19 compound treatment 877130.0 232000.0 0.62 593120.0 31500.0 0.09 0.5 0.798 3187840 PK04_101271 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N20 compound treatment 813630.0 169000.0 0.45 836330.0 275000.0 0.75 0.8522 0.9698 3187841 PK04_101272 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N21 compound treatment 625280.0 -19500.0 -0.05 506590.0 -55000.0 -0.15 -0.1436 -0.8991 3069973 PK04_101273 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N22 compound treatment 722950.0 78200.0 0.21 543210.0 -18400.0 -0.05 0.1119 0.5212 3187841 PK04_101274 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N23 compound treatment 827330.0 183000.0 0.49 805620.0 244000.0 0.67 0.8185 0.9878 3187842 PK04_101275 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 N24 compound treatment 861380.0 217000.0 0.58 778720.0 217000.0 0.6 0.8306 0.9999 3187843 PK04_101276 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O01 compound treatment 353180.0 -292000.0 -0.78 510560.0 -51000.0 -0.14 -0.6498 -0.8211 3069974 PK04_101277 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O02 compound treatment 780530.0 136000.0 0.36 603860.0 42300.0 0.12 0.3384 0.889 3187957 PK04_101278 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O03 compound treatment 752910.0 108000.0 0.29 439910.0 -122000.0 -0.33 -0.032 -0.0725 3187958 PK04_101279 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O04 compound treatment 724520.0 79700.0 0.21 574010.0 12400.0 0.03 0.1747 0.81 3069975 PK04_101280 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O05 compound treatment 764770.0 120000.0 0.32 389460.0 -172000.0 -0.47 -0.1076 -0.1884 3187959 PK04_101281 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O06 compound treatment 697710.0 52900.0 0.14 646270.0 84700.0 0.23 0.2643 0.9715 3187960 PK04_101282 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O07 compound treatment 562100.0 -82700.0 -0.22 570830.0 9240.0 0.03 -0.1382 -0.6218 3069976 PK04_101283 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O08 compound treatment 431840.0 -213000.0 -0.57 505690.0 -55900.0 -0.15 -0.5107 -0.8669 3187961 PK04_101284 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O09 compound treatment 565480.0 -79300.0 -0.21 402490.0 -159000.0 -0.44 -0.4587 -0.9448 3069977 PK04_101285 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O10 compound treatment 696580.0 51800.0 0.14 674730.0 113000.0 0.31 0.3175 0.9336 3187962 PK04_101286 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O11 mock treatment 708410.0 63600.0 0.17 494840.0 -66800.0 -0.18 -0.0094 -0.0377 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O12 mock treatment 777050.0 132000.0 0.35 504870.0 -56700.0 -0.16 0.1397 0.3618 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O13 compound treatment 620530.0 -24300.0 -0.06 669210.0 108000.0 0.3 0.1631 0.5392 3187963 PK04_101287 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O14 compound treatment 681830.0 37000.0 0.1 590780.0 29200.0 0.08 0.1266 0.9945 3069978 PK04_101288 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O15 compound treatment 532190.0 -113000.0 -0.3 570290.0 8700.0 0.02 -0.1958 -0.6489 3187964 PK04_101289 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O16 compound treatment 726010.0 81200.0 0.22 561710.0 120.0 0.0 0.1536 0.7082 3187965 PK04_101290 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O17 compound treatment 606400.0 -38400.0 -0.1 718730.0 157000.0 0.43 0.2326 0.5244 3069979 PK04_101291 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O18 compound treatment 816000.0 171000.0 0.46 628480.0 66900.0 0.18 0.4532 0.9197 3187966 PK04_101292 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O19 compound treatment 726200.0 81400.0 0.22 622950.0 61400.0 0.17 0.2729 0.992 3187967 PK04_101293 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O20 compound treatment 518530.0 -126000.0 -0.34 674360.0 113000.0 0.31 -0.0195 -0.0427 3069980 PK04_101294 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O21 compound treatment 686350.0 41600.0 0.11 554050.0 -7540.0 -0.02 0.0639 0.5655 3187968 PK04_101295 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O22 compound treatment 716050.0 71300.0 0.19 649660.0 88100.0 0.24 0.3056 0.993 3069981 PK04_101296 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O23 compound treatment 665630.0 20800.0 0.06 658630.0 97000.0 0.27 0.2277 0.8368 3187969 PK04_101297 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 O24 compound treatment 821890.0 177000.0 0.47 755240.0 194000.0 0.53 0.7104 0.9983 3187970 PK04_101298 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P01 compound treatment 436900.0 -208000.0 -0.56 376320.0 -185000.0 -0.51 -0.7523 -0.999 3069982 PK04_101299 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P02 compound treatment 355410.0 -289000.0 -0.77 421990.0 -140000.0 -0.38 -0.8176 -0.9476 3187843 PK04_101300 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P03 compound treatment 377230.0 -268000.0 -0.71 412190.0 -149000.0 -0.41 -0.7954 -0.9653 3187971 PK04_101301 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P04 compound treatment 666310.0 21500.0 0.06 426080.0 -136000.0 -0.37 -0.2224 -0.5908 3069983 PK04_101302 OCCOCCN(C(C(=O)N(CC=C)Cc1ccccc1)c2cccs2)C(=O)/C=C\C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P05 compound treatment 391700.0 -253000.0 -0.68 393570.0 -168000.0 -0.46 -0.8042 -0.9826 3187972 PK04_101303 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P06 compound treatment 465330.0 -179000.0 -0.48 362310.0 -199000.0 -0.55 -0.7258 -0.9978 3187973 PK04_101304 OCCOCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P07 compound treatment 394950.0 -250000.0 -0.67 422650.0 -139000.0 -0.38 -0.7416 -0.9648 3069985 PK04_101305 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P08 compound treatment 420660.0 -224000.0 -0.6 313930.0 -248000.0 -0.68 -0.9041 -0.998 3187974 PK04_101306 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P09 compound treatment 444430.0 -200000.0 -0.54 378400.0 -183000.0 -0.5 -0.734 -0.9995 3187975 PK04_101307 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P10 compound treatment 419010.0 -226000.0 -0.6 354440.0 -207000.0 -0.57 -0.8286 -0.9996 3187974 PK04_101308 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P11 mock treatment 622820.0 -22000.0 -0.06 386740.0 -175000.0 -0.48 -0.3809 -0.7877 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P12 mock treatment 396730.0 -248000.0 -0.66 353810.0 -208000.0 -0.57 -0.8719 -0.9972 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P13 compound treatment 279240.0 -366000.0 -0.98 322790.0 -239000.0 -0.66 -1.154 -0.9812 3069986 PK04_101309 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P14 compound treatment 490690.0 -154000.0 -0.41 404000.0 -158000.0 -0.43 -0.597 -0.9997 3069301 PK04_101310 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P15 compound treatment 329090.0 -316000.0 -0.84 432130.0 -129000.0 -0.36 -0.8476 -0.9262 3187976 PK04_101311 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P16 compound treatment 556730.0 -88100.0 -0.24 450660.0 -111000.0 -0.3 -0.3817 -0.9918 3069301 PK04_101312 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P17 compound treatment 465650.0 -179000.0 -0.48 379930.0 -182000.0 -0.5 -0.691 -0.9998 3187977 PK04_101313 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P18 compound treatment 564160.0 -80600.0 -0.22 412090.0 -150000.0 -0.41 -0.4425 -0.9547 3069302 PK04_101314 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P19 compound treatment 500190.0 -145000.0 -0.39 400850.0 -161000.0 -0.44 -0.5851 -0.9978 3189130 PK04_101315 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P20 compound treatment 403540.0 -241000.0 -0.64 417660.0 -144000.0 -0.4 -0.7351 -0.9724 3069302 PK04_101316 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P21 compound treatment 503520.0 -141000.0 -0.38 470640.0 -91000.0 -0.25 -0.4434 -0.9799 3189131 PK04_101317 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P22 compound treatment 417670.0 -227000.0 -0.61 422010.0 -140000.0 -0.38 -0.6999 -0.9755 3069303 PK04_101318 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P23 compound treatment 491060.0 -154000.0 -0.41 464540.0 -97100.0 -0.27 -0.4787 -0.9781 3069685 PK04_101319 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2101 P24 compound treatment 552600.0 -92200.0 -0.25 425810.0 -136000.0 -0.37 -0.4377 -0.9797 3069303 PK04_101320 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A01 compound treatment 628480.0 19100.0 0.05 478830.0 -30700.0 -0.08 -0.0235 -0.2392 3188092 PK04_102001 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A02 compound treatment 134160.0 -475000.0 -1.27 143870.0 -366000.0 -1.0 -1.6074 -0.9932 3188093 PK04_102002 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A03 compound treatment 172570.0 -437000.0 -1.17 337830.0 -172000.0 -0.47 -1.1583 -0.9205 3069304 PK04_102003 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccccc43 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A04 compound treatment 315950.0 -293000.0 -0.78 320480.0 -189000.0 -0.52 -0.9212 -0.98 3188094 PK04_102004 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A05 compound treatment 261150.0 -348000.0 -0.93 305010.0 -205000.0 -0.56 -1.0547 -0.9708 3069305 PK04_102005 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A06 compound treatment 270260.0 -339000.0 -0.91 326720.0 -183000.0 -0.5 -0.9954 -0.9612 3188095 PK04_102006 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A07 compound treatment 463170.0 -146000.0 -0.39 367970.0 -142000.0 -0.39 -0.551 -1.0 3069306 PK04_102007 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A08 compound treatment 172920.0 -436000.0 -1.17 134370.0 -375000.0 -1.03 -1.5527 -0.9981 3188096 PK04_102008 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A09 compound treatment 281390.0 -328000.0 -0.88 271730.0 -238000.0 -0.65 -1.0811 -0.9895 3188097 PK04_102009 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A10 compound treatment 229600.0 -380000.0 -1.01 219310.0 -290000.0 -0.8 -1.2807 -0.9929 3069307 PK04_102010 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A11 compound treatment 261600.0 -348000.0 -0.93 221510.0 -288000.0 -0.79 -1.216 -0.9968 3188098 PK04_102011 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A12 compound treatment 184040.0 -425000.0 -1.14 200690.0 -309000.0 -0.85 -1.4029 -0.9896 3069308 PK04_102012 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A13 mock treatment 370280.0 -239000.0 -0.64 609080.0 99600.0 0.27 -0.2583 -0.3719 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A14 mock treatment 549850.0 -59600.0 -0.16 671680.0 162000.0 0.45 0.2023 0.428 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A15 compound treatment 277860.0 -332000.0 -0.89 242940.0 -267000.0 -0.73 -1.1437 -0.9955 3188099 PK04_102013 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A16 compound treatment 308670.0 -301000.0 -0.8 275940.0 -234000.0 -0.64 -1.0214 -0.9938 3188100 PK04_102014 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A17 compound treatment 172570.0 -437000.0 -1.17 192280.0 -317000.0 -0.87 -1.4409 -0.9896 3069309 PK04_102015 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@]5(O[C@H](CCO)[C@H]([C@@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A18 compound treatment 321230.0 -288000.0 -0.77 252640.0 -257000.0 -0.71 -1.0429 -0.999 3188101 PK04_102016 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A19 compound treatment 194650.0 -415000.0 -1.11 182150.0 -327000.0 -0.9 -1.4189 -0.9946 3069310 PK04_102017 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A20 compound treatment 335560.0 -274000.0 -0.73 156900.0 -353000.0 -0.97 -1.2017 -0.9904 3188102 PK04_102018 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@@]5(O[C@@H](CCO)[C@@H]([C@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A21 compound treatment 408450.0 -201000.0 -0.54 531060.0 21500.0 0.06 -0.3377 -0.6254 3188103 PK04_102019 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A22 compound treatment 194880.0 -415000.0 -1.11 147570.0 -362000.0 -0.99 -1.4855 -0.9985 3069311 PK04_102020 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A23 compound treatment 265630.0 -344000.0 -0.92 233120.0 -276000.0 -0.76 -1.1858 -0.9955 3188104 PK04_102021 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 A24 compound treatment 647310.0 37900.0 0.1 331400.0 -178000.0 -0.49 -0.2742 -0.5491 3188105 PK04_102022 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B01 compound treatment 614850.0 5440.0 0.01 834580.0 325000.0 0.89 0.6413 0.7185 3069350 PK04_102023 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B02 compound treatment 529020.0 -80400.0 -0.21 561000.0 51500.0 0.14 -0.0519 -0.2018 3188106 PK04_102024 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B03 compound treatment 778400.0 169000.0 0.45 752890.0 243000.0 0.67 0.7916 0.9818 3069351 PK04_102025 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCCCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B04 compound treatment 666970.0 57600.0 0.15 236800.0 -273000.0 -0.75 -0.4207 -0.5504 3188107 PK04_102026 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B05 compound treatment 746450.0 137000.0 0.37 597800.0 88300.0 0.24 0.4302 0.98 3188221 PK04_102027 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B06 compound treatment 489400.0 -120000.0 -0.32 294790.0 -215000.0 -0.59 -0.6435 -0.959 3069352 PK04_102028 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B07 compound treatment 417250.0 -192000.0 -0.51 311070.0 -198000.0 -0.54 -0.7482 -0.9996 3188222 PK04_102029 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B08 compound treatment 233860.0 -376000.0 -1.0 338310.0 -171000.0 -0.47 -1.0416 -0.9403 3069353 PK04_102030 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B09 compound treatment 666290.0 56900.0 0.15 575390.0 65900.0 0.18 0.2353 0.9962 3188223 PK04_102031 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B10 compound treatment 263270.0 -346000.0 -0.92 268370.0 -241000.0 -0.66 -1.1219 -0.9866 3188224 PK04_102032 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B11 compound treatment 371750.0 -238000.0 -0.63 321570.0 -188000.0 -0.52 -0.8137 -0.9947 3069354 PK04_102033 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B12 compound treatment 268820.0 -341000.0 -0.91 187880.0 -322000.0 -0.88 -1.2676 -0.9999 3188225 PK04_102034 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B13 mock treatment 439840.0 -170000.0 -0.45 490510.0 -19000.0 -0.05 -0.3571 -0.7834 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B14 mock treatment 742490.0 133000.0 0.36 609490.0 100000.0 0.27 0.4454 0.9918 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B15 compound treatment 477850.0 -132000.0 -0.35 284960.0 -225000.0 -0.62 -0.6844 -0.9645 3188226 PK04_102035 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B16 compound treatment 579040.0 -30400.0 -0.08 318030.0 -191000.0 -0.53 -0.4291 -0.8067 3069355 PK04_102036 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B17 compound treatment 290440.0 -319000.0 -0.85 312450.0 -197000.0 -0.54 -0.985 -0.976 3188227 PK04_102037 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B18 compound treatment 406120.0 -203000.0 -0.54 250110.0 -259000.0 -0.71 -0.8875 -0.991 3069356 PK04_102038 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B19 compound treatment 336160.0 -273000.0 -0.73 368120.0 -141000.0 -0.39 -0.7906 -0.9563 3188228 PK04_102039 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B20 compound treatment 544720.0 -64700.0 -0.17 553320.0 43800.0 0.12 -0.0371 -0.1764 3188229 PK04_102040 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B21 compound treatment 449870.0 -160000.0 -0.43 488960.0 -20600.0 -0.06 -0.3412 -0.7938 3069357 PK04_102041 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B22 compound treatment 426760.0 -183000.0 -0.49 307280.0 -202000.0 -0.56 -0.7376 -0.9979 3188230 PK04_102042 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(I)c6)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B23 compound treatment 416290.0 -193000.0 -0.52 413000.0 -96500.0 -0.26 -0.5521 -0.9521 3069358 PK04_102043 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 B24 compound treatment 347420.0 -262000.0 -0.7 329650.0 -180000.0 -0.49 -0.844 -0.9854 3188231 PK04_102044 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C01 compound treatment 518560.0 -90800.0 -0.24 695410.0 186000.0 0.51 0.1893 0.335 3188232 PK04_102045 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C02 compound treatment 362460.0 -247000.0 -0.66 284960.0 -225000.0 -0.62 -0.9023 -0.9994 3069359 PK04_102046 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C03 compound treatment 446720.0 -163000.0 -0.43 504890.0 -4620.0 -0.01 -0.3162 -0.7274 3188233 PK04_102047 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C04 compound treatment 343550.0 -266000.0 -0.71 551600.0 42100.0 0.12 -0.4204 -0.5844 3188234 PK04_102048 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C05 compound treatment 641010.0 31600.0 0.08 534410.0 24900.0 0.07 0.108 0.9945 3069360 PK04_102049 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C06 compound treatment 14240.0 -595000.0 -1.59 81810.0 -428000.0 -1.17 -1.9544 -0.9889 3188235 PK04_102050 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C07 compound treatment 639390.0 30000.0 0.08 356830.0 -153000.0 -0.42 -0.2398 -0.5619 3069393 PK04_102051 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C08 compound treatment 218840.0 -391000.0 -1.04 237540.0 -272000.0 -0.75 -1.2656 -0.9866 3188236 PK04_102052 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C09 compound treatment 334240.0 -275000.0 -0.73 211360.0 -298000.0 -0.82 -1.0985 -0.9986 3069394 PK04_102053 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C10 compound treatment 200930.0 -408000.0 -1.09 131810.0 -378000.0 -1.04 -1.5047 -0.9997 3188352 PK04_102054 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C11 mock treatment 715390.0 106000.0 0.28 544320.0 34800.0 0.1 0.2677 0.8961 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C12 mock treatment 679240.0 69800.0 0.19 170720.0 -339000.0 -0.93 -0.5258 -0.5543 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C13 compound treatment 424130.0 -185000.0 -0.49 655970.0 146000.0 0.4 -0.0656 -0.1029 3188353 PK04_102055 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C14 compound treatment 239090.0 -370000.0 -0.99 195240.0 -314000.0 -0.86 -1.3095 -0.9977 3069395 PK04_102056 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C15 mock treatment 298190.0 -311000.0 -0.83 533920.0 24400.0 0.07 -0.5404 -0.648 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C16 mock treatment 350280.0 -259000.0 -0.69 281840.0 -228000.0 -0.63 -0.9314 -0.9987 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C17 compound treatment 376250.0 -233000.0 -0.62 164190.0 -345000.0 -0.95 -1.1107 -0.9792 3188354 PK04_102057 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C18 compound treatment 180170.0 -429000.0 -1.15 166990.0 -343000.0 -0.94 -1.4756 -0.9952 3069396 PK04_102058 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C19 compound treatment 246260.0 -363000.0 -0.97 178640.0 -331000.0 -0.91 -1.3282 -0.9995 3188355 PK04_102059 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C20 compound treatment 400890.0 -209000.0 -0.56 183880.0 -326000.0 -0.89 -1.026 -0.9741 3188356 PK04_102060 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C21 compound treatment 287160.0 -322000.0 -0.86 187040.0 -322000.0 -0.89 -1.2346 -0.9999 3069397 PK04_102061 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C22 compound treatment 308990.0 -300000.0 -0.8 224260.0 -285000.0 -0.78 -1.1212 -0.9999 3188357 PK04_102062 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C23 compound treatment 221600.0 -388000.0 -1.04 261870.0 -248000.0 -0.68 -1.2132 -0.9791 3188358 PK04_102063 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 C24 compound treatment 523070.0 -86300.0 -0.23 183540.0 -326000.0 -0.89 -0.7959 -0.8612 3069398 PK04_102064 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D01 compound treatment 721040.0 112000.0 0.3 424380.0 -85100.0 -0.23 0.0456 0.1203 3188359 PK04_102065 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D02 compound treatment 581550.0 -27900.0 -0.07 375250.0 -134000.0 -0.37 -0.3133 -0.833 3069399 PK04_102066 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(I)cc6)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D03 compound treatment 402370.0 -207000.0 -0.55 359910.0 -150000.0 -0.41 -0.6815 -0.9893 3188360 PK04_102067 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D04 compound treatment 654740.0 45300.0 0.12 571900.0 62400.0 0.17 0.2067 0.9856 3188361 PK04_102068 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D05 compound treatment 415540.0 -194000.0 -0.52 325860.0 -184000.0 -0.5 -0.7227 -0.9999 3069400 PK04_102069 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D06 compound treatment 560260.0 -49100.0 -0.13 550100.0 40600.0 0.11 -0.014 -0.0815 3188362 PK04_102070 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D07 compound treatment 533470.0 -75900.0 -0.2 432970.0 -76500.0 -0.21 -0.292 -0.9998 3188363 PK04_102071 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D08 compound treatment 386080.0 -223000.0 -0.6 790520.0 281000.0 0.77 0.1237 0.1269 3069401 PK04_102072 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D09 compound treatment 336030.0 -273000.0 -0.73 428350.0 -81200.0 -0.22 -0.6739 -0.8827 3188364 PK04_102073 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D10 compound treatment 638090.0 28700.0 0.08 348360.0 -161000.0 -0.44 -0.2587 -0.5761 3069402 PK04_102074 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D11 mock treatment 729890.0 120000.0 0.32 537540.0 28000.0 0.08 0.282 0.8522 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D12 mock treatment 568870.0 -40500.0 -0.11 307680.0 -202000.0 -0.55 -0.4684 -0.8296 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D13 compound treatment 381830.0 -228000.0 -0.61 404410.0 -105000.0 -0.29 -0.6339 -0.942 3069403 PK04_102075 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D14 compound treatment 213170.0 -396000.0 -1.06 131010.0 -379000.0 -1.04 -1.4832 -1.0 3188365 PK04_102076 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D15 mock treatment 587650.0 -21800.0 -0.06 294020.0 -215000.0 -0.59 -0.4594 -0.7729 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D16 mock treatment 697310.0 87900.0 0.23 182630.0 -327000.0 -0.9 -0.4686 -0.5051 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D17 compound treatment 235040.0 -374000.0 -1.0 415950.0 -93600.0 -0.26 -0.8887 -0.8608 3188366 PK04_102077 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D18 compound treatment 693790.0 84400.0 0.23 448000.0 -61500.0 -0.17 0.04 0.1419 3069404 PK04_102078 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D19 compound treatment 691520.0 82100.0 0.22 388750.0 -121000.0 -0.33 -0.0794 -0.1996 3188367 PK04_102079 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D20 compound treatment 144710.0 -465000.0 -1.24 31000.0 -479000.0 -1.31 -1.8066 -0.9996 3069405 PK04_102080 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D21 compound treatment 504180.0 -105000.0 -0.28 232100.0 -277000.0 -0.76 -0.7373 -0.9082 3188368 PK04_102081 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D22 compound treatment 597370.0 -12000.0 -0.03 397890.0 -112000.0 -0.31 -0.2394 -0.777 3069440 PK04_102082 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D23 compound treatment 529340.0 -80100.0 -0.21 348830.0 -161000.0 -0.44 -0.4632 -0.9447 3188485 PK04_102083 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 D24 compound treatment 547070.0 -62300.0 -0.17 313980.0 -196000.0 -0.54 -0.4973 -0.8848 3069441 PK04_102084 O[C@H](CC=C)c1ccc(O)c(F)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E01 mock treatment 744480.0 135000.0 0.36 820480.0 311000.0 0.85 0.8588 0.9266 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E02 mock treatment 774880.0 165000.0 0.44 800570.0 291000.0 0.8 0.8776 0.961 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E03 compound treatment 590470.0 -18900.0 -0.05 465080.0 -44400.0 -0.12 -0.122 -0.924 3069442 PK04_102085 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E04 compound treatment 269120.0 -340000.0 -0.91 325780.0 -184000.0 -0.5 -0.9994 -0.9614 3188486 PK04_102086 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E05 compound treatment 262560.0 -347000.0 -0.93 202570.0 -307000.0 -0.84 -1.251 -0.9989 3188487 PK04_102087 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E06 compound treatment 492170.0 -117000.0 -0.31 327800.0 -182000.0 -0.5 -0.5742 -0.9748 3069443 PK04_102088 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E07 compound treatment 261440.0 -348000.0 -0.93 397280.0 -112000.0 -0.31 -0.8751 -0.8937 3188488 PK04_102089 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E08 compound treatment 192760.0 -417000.0 -1.11 216090.0 -293000.0 -0.81 -1.3565 -0.9874 3188489 PK04_102090 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E09 mock treatment 508830.0 -101000.0 -0.27 408800.0 -101000.0 -0.28 -0.3855 -0.9999 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E10 mock treatment 609390.0 -19.5 0.0 331070.0 -178000.0 -0.49 -0.3464 -0.7072 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E11 compound treatment 313880.0 -296000.0 -0.79 182450.0 -327000.0 -0.9 -1.1931 -0.9979 3069444 PK04_102091 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E12 compound treatment 217600.0 -392000.0 -1.05 220560.0 -289000.0 -0.79 -1.3009 -0.9907 3188490 PK04_102092 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E13 compound treatment 311680.0 -298000.0 -0.8 226420.0 -283000.0 -0.78 -1.1119 -0.9999 3069445 PK04_102093 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E14 compound treatment 386680.0 -223000.0 -0.59 221380.0 -288000.0 -0.79 -0.98 -0.9901 3188491 PK04_102094 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E15 compound treatment 403680.0 -206000.0 -0.55 214880.0 -295000.0 -0.81 -0.9605 -0.9823 3188492 PK04_102095 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E16 compound treatment 679000.0 69600.0 0.19 592410.0 82900.0 0.23 0.2924 0.9949 3069446 PK04_102096 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E17 mock treatment 794660.0 185000.0 0.49 266490.0 -243000.0 -0.67 -0.1219 -0.1468 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E18 mock treatment 438750.0 -171000.0 -0.46 540270.0 30800.0 0.08 -0.2626 -0.5665 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E19 compound treatment 258120.0 -351000.0 -0.94 171590.0 -338000.0 -0.93 -1.3195 -1.0 3188493 PK04_102097 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E20 compound treatment 623060.0 13700.0 0.04 207690.0 -302000.0 -0.83 -0.5601 -0.6753 3188494 PK04_102098 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E21 compound treatment 309860.0 -300000.0 -0.8 218760.0 -291000.0 -0.8 -1.1302 -1.0 3069448 PK04_102099 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E22 compound treatment 440600.0 -169000.0 -0.45 289240.0 -220000.0 -0.6 -0.7464 -0.9895 3188495 PK04_102100 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E23 compound treatment 273310.0 -336000.0 -0.9 214660.0 -295000.0 -0.81 -1.2072 -0.9987 3069450 PK04_102101 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 E24 compound treatment 358240.0 -251000.0 -0.67 263520.0 -246000.0 -0.68 -0.9519 -1.0 3188496 PK04_102102 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F01 mock treatment 586110.0 -23300.0 -0.06 788930.0 279000.0 0.77 0.4984 0.6476 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F02 mock treatment 595430.0 -14000.0 -0.04 647120.0 138000.0 0.38 0.2407 0.6341 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F03 compound treatment 627700.0 18300.0 0.05 656250.0 147000.0 0.4 0.3194 0.7871 3188497 PK04_102103 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F04 compound treatment 451840.0 -158000.0 -0.42 364970.0 -145000.0 -0.4 -0.5782 -0.9996 3069264 PK04_102104 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F05 compound treatment 424650.0 -185000.0 -0.49 579760.0 70200.0 0.19 -0.2126 -0.4012 3069265 PK04_102105 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F06 compound treatment 204030.0 -405000.0 -1.08 138920.0 -371000.0 -1.02 -1.4851 -0.9995 3188498 PK04_102106 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F07 compound treatment 244800.0 -365000.0 -0.97 252890.0 -257000.0 -0.7 -1.1868 -0.9874 3188499 PK04_102107 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F08 compound treatment 537470.0 -71900.0 -0.19 646190.0 137000.0 0.38 0.1295 0.3071 3069441 PK04_102108 O[C@H](CC=C)c1ccc(O)c(F)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F09 mock treatment 782400.0 173000.0 0.46 308170.0 -201000.0 -0.55 -0.0641 -0.089 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F10 mock treatment 393790.0 -216000.0 -0.58 462270.0 -47200.0 -0.13 -0.4989 -0.8452 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F11 compound treatment 417860.0 -192000.0 -0.51 279390.0 -230000.0 -0.63 -0.8085 -0.9945 3188500 PK04_102109 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F12 compound treatment 418170.0 -191000.0 -0.51 296700.0 -213000.0 -0.58 -0.7743 -0.9978 3069270 PK04_102110 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F13 compound treatment 275160.0 -334000.0 -0.89 259450.0 -250000.0 -0.69 -1.1167 -0.9916 3188501 PK04_102111 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F14 compound treatment 619570.0 10200.0 0.03 224530.0 -285000.0 -0.78 -0.534 -0.6822 3188502 PK04_102112 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F15 compound treatment 455920.0 -153000.0 -0.41 392190.0 -117000.0 -0.32 -0.5176 -0.9929 3188623 PK04_102113 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F16 compound treatment 466300.0 -143000.0 -0.38 235240.0 -274000.0 -0.75 -0.8027 -0.9506 3069312 PK04_102114 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F17 mock treatment 378100.0 -231000.0 -0.62 282510.0 -227000.0 -0.62 -0.8775 -1.0 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F18 mock treatment 534180.0 -75200.0 -0.2 427490.0 -82000.0 -0.23 -0.3013 -0.9984 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F19 compound treatment 364910.0 -244000.0 -0.65 382750.0 -127000.0 -0.35 -0.7079 -0.9566 3188624 PK04_102115 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F20 compound treatment 659620.0 50200.0 0.13 544320.0 34800.0 0.1 0.1624 0.9862 3069314 PK04_102116 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F21 compound treatment 613780.0 4370.0 0.01 348320.0 -161000.0 -0.44 -0.3047 -0.6882 3069316 PK04_102117 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F22 compound treatment 418630.0 -191000.0 -0.51 133350.0 -376000.0 -1.03 -1.0906 -0.947 3188625 PK04_102118 O[C@@H](CC=C)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F23 compound treatment 530040.0 -79400.0 -0.21 477960.0 -31600.0 -0.09 -0.2112 -0.922 3188626 PK04_102119 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 F24 compound treatment 762670.0 153000.0 0.41 513830.0 4320.0 0.01 0.2978 0.7273 3069318 PK04_102120 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G01 compound treatment 591040.0 -18400.0 -0.05 569500.0 60000.0 0.16 0.0818 0.4758 3069320 PK04_102121 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO)nn2)/C=C/C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G02 compound treatment 404330.0 -205000.0 -0.55 720160.0 211000.0 0.58 0.0216 0.0271 3188627 PK04_102122 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G03 mock treatment 731520.0 122000.0 0.33 757440.0 248000.0 0.68 0.7119 0.9432 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G04 mock treatment 533280.0 -76100.0 -0.2 820270.0 311000.0 0.85 0.4595 0.5239 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G05 compound treatment 183150.0 -426000.0 -1.14 631960.0 122000.0 0.34 -0.5674 -0.4779 3069321 PK04_102123 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G06 compound treatment 224640.0 -385000.0 -1.03 198210.0 -311000.0 -0.85 -1.331 -0.9958 3188628 PK04_102124 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G07 compound treatment 229440.0 -380000.0 -1.01 293630.0 -216000.0 -0.59 -1.1367 -0.9672 3069362 PK04_102125 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4ccccc43 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G08 compound treatment 414720.0 -195000.0 -0.52 359110.0 -150000.0 -0.41 -0.6597 -0.9935 3188629 PK04_102126 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G09 compound treatment 215210.0 -394000.0 -1.05 131260.0 -378000.0 -1.04 -1.4788 -1.0 3188630 PK04_102127 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G10 compound treatment 599520.0 -9890.0 -0.03 470280.0 -39200.0 -0.11 -0.0948 -0.8552 3188631 PK04_102128 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G11 compound treatment 192420.0 -417000.0 -1.11 203370.0 -306000.0 -0.84 -1.3819 -0.9904 3069365 PK04_102129 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G12 compound treatment 810340.0 201000.0 0.54 554560.0 45000.0 0.12 0.4669 0.8478 3188632 PK04_102130 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G13 compound treatment 209020.0 -400000.0 -1.07 230180.0 -279000.0 -0.77 -1.2985 -0.9867 3069368 PK04_102131 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccccc43 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G14 compound treatment 160490.0 -449000.0 -1.2 156010.0 -354000.0 -0.97 -1.5341 -0.9945 3069370 PK04_102132 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G15 compound treatment 518180.0 -91200.0 -0.24 174930.0 -335000.0 -0.92 -0.8218 -0.8648 3188633 PK04_102133 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G16 compound treatment 228320.0 -381000.0 -1.02 241150.0 -268000.0 -0.74 -1.2407 -0.9874 3188634 PK04_102134 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G17 compound treatment 232450.0 -377000.0 -1.01 90200.0 -419000.0 -1.15 -1.526 -0.9978 3188635 PK04_102135 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G18 compound treatment 512190.0 -97200.0 -0.26 314030.0 -195000.0 -0.54 -0.5631 -0.9445 3069408 PK04_102136 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G19 mock treatment 525290.0 -84100.0 -0.22 673870.0 164000.0 0.45 0.1602 0.3178 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G20 mock treatment 311200.0 -298000.0 -0.8 556580.0 47100.0 0.13 -0.4718 -0.5847 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G21 compound treatment 284730.0 -325000.0 -0.87 172480.0 -337000.0 -0.93 -1.2675 -0.9995 3188636 PK04_102137 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G22 compound treatment 249540.0 -360000.0 -0.96 210240.0 -299000.0 -0.82 -1.2607 -0.9969 3188637 PK04_102138 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G23 compound treatment 392060.0 -217000.0 -0.58 328190.0 -181000.0 -0.5 -0.7625 -0.9971 3069412 PK04_102139 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 G24 compound treatment 398820.0 -211000.0 -0.56 329330.0 -180000.0 -0.49 -0.7475 -0.9979 3188638 PK04_102140 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H01 compound treatment 423120.0 -186000.0 -0.5 521850.0 12300.0 0.03 -0.3279 -0.6574 3188639 PK04_102141 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H02 compound treatment 720240.0 111000.0 0.3 784320.0 275000.0 0.75 0.7428 0.9165 3069414 PK04_102142 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H03 mock treatment 478560.0 -131000.0 -0.35 577840.0 68300.0 0.19 -0.1145 -0.2886 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H04 mock treatment 672900.0 63500.0 0.17 475490.0 -34000.0 -0.09 0.0539 0.2782 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H05 compound treatment 312480.0 -297000.0 -0.79 410010.0 -99500.0 -0.27 -0.754 -0.8988 3188755 PK04_102143 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H06 compound treatment 675080.0 65700.0 0.18 235610.0 -274000.0 -0.75 -0.4077 -0.528 3188362 PK04_102144 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H07 compound treatment 256440.0 -353000.0 -0.94 580990.0 71500.0 0.2 -0.5279 -0.5482 3188756 PK04_102145 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H08 compound treatment 323690.0 -286000.0 -0.76 250240.0 -259000.0 -0.71 -1.043 -0.9994 3069452 PK04_102146 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H09 compound treatment 337300.0 -272000.0 -0.73 258320.0 -251000.0 -0.69 -1.0016 -0.9997 3188757 PK04_102147 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H10 compound treatment 282660.0 -327000.0 -0.87 169040.0 -340000.0 -0.93 -1.2781 -0.9994 3069454 PK04_102148 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H11 compound treatment 191360.0 -418000.0 -1.12 256720.0 -253000.0 -0.69 -1.2803 -0.9738 3188758 PK04_102149 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H12 compound treatment 534420.0 -75000.0 -0.2 198040.0 -311000.0 -0.86 -0.7463 -0.8497 3069456 PK04_102150 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H13 compound treatment 270400.0 -339000.0 -0.91 285860.0 -224000.0 -0.61 -1.0745 -0.9821 3188759 PK04_102151 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H14 compound treatment 92170.0 -517000.0 -1.38 22880.0 -487000.0 -1.34 -1.9216 -0.9999 3069458 PK04_102152 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H15 compound treatment 230200.0 -379000.0 -1.01 264370.0 -245000.0 -0.67 -1.1921 -0.9803 3188760 PK04_102153 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H16 compound treatment 852000.0 243000.0 0.65 378420.0 -131000.0 -0.36 0.2037 0.2748 3069460 PK04_102154 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H17 compound treatment 314730.0 -295000.0 -0.79 225560.0 -284000.0 -0.78 -1.1078 -1.0 3188761 PK04_102155 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H18 compound treatment 237540.0 -372000.0 -0.99 18420.0 -491000.0 -1.35 -1.6557 -0.9887 3069461 PK04_102156 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H19 mock treatment 508270.0 -101000.0 -0.27 495860.0 -13700.0 -0.04 -0.2175 -0.7976 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H20 mock treatment 733700.0 124000.0 0.33 762600.0 253000.0 0.69 0.7261 0.9429 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H21 compound treatment 409640.0 -200000.0 -0.53 405550.0 -104000.0 -0.29 -0.5791 -0.957 3188762 PK04_102157 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H22 compound treatment 333680.0 -276000.0 -0.74 188000.0 -322000.0 -0.88 -1.1449 -0.9959 3069504 PK04_102158 O[C@H](CC=C)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H23 compound treatment 464360.0 -145000.0 -0.39 293640.0 -216000.0 -0.59 -0.693 -0.9788 3188763 PK04_102159 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 H24 compound treatment 564280.0 -45100.0 -0.12 494050.0 -15500.0 -0.04 -0.1153 -0.9018 3069401 PK04_102160 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I01 compound treatment 730850.0 121000.0 0.32 435900.0 -73600.0 -0.2 0.0865 0.2262 3069507 PK04_102161 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I02 compound treatment 217530.0 -392000.0 -1.05 298950.0 -211000.0 -0.58 -1.1489 -0.9608 3188764 PK04_102162 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I03 compound treatment 595430.0 -14000.0 -0.04 657630.0 148000.0 0.41 0.2611 0.6395 3188765 PK04_102163 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I04 compound treatment 209550.0 -400000.0 -1.07 177040.0 -332000.0 -0.91 -1.4006 -0.9969 3069594 PK04_102164 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I05 mock treatment 661930.0 52500.0 0.14 764270.0 255000.0 0.7 0.5938 0.8324 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I06 mock treatment 732810.0 123000.0 0.33 782770.0 273000.0 0.75 0.7635 0.9318 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I07 compound treatment 660490.0 51100.0 0.14 743060.0 234000.0 0.64 0.5499 0.8388 3188766 PK04_102165 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I08 compound treatment 744160.0 135000.0 0.36 392890.0 -117000.0 -0.32 0.0281 0.0583 3188767 PK04_102166 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I09 compound treatment 508920.0 -100000.0 -0.27 255730.0 -254000.0 -0.7 -0.6825 -0.914 3069598 PK04_102167 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I10 compound treatment 472480.0 -137000.0 -0.37 280920.0 -229000.0 -0.63 -0.7024 -0.967 3188768 PK04_102168 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I11 compound treatment 136040.0 -473000.0 -1.26 151960.0 -358000.0 -0.98 -1.5882 -0.9922 3188769 PK04_102169 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I12 compound treatment 183380.0 -426000.0 -1.14 211850.0 -298000.0 -0.82 -1.3825 -0.9868 3069636 PK04_102170 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I13 compound treatment 242950.0 -366000.0 -0.98 215880.0 -294000.0 -0.81 -1.2622 -0.9954 3188770 PK04_102171 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I14 compound treatment 186830.0 -423000.0 -1.13 161150.0 -348000.0 -0.96 -1.4744 -0.9966 3188771 PK04_102172 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I15 compound treatment 612160.0 2750.0 0.01 581680.0 72200.0 0.2 0.1453 0.7328 3069640 PK04_102173 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I16 compound treatment 223360.0 -386000.0 -1.03 222780.0 -287000.0 -0.79 -1.2858 -0.9911 3188888 PK04_102174 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I17 compound treatment 215840.0 -394000.0 -1.05 310760.0 -199000.0 -0.55 -1.1292 -0.9534 3069645 PK04_102175 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I18 compound treatment 581600.0 -27800.0 -0.07 564930.0 55400.0 0.15 0.0551 0.3252 3188889 PK04_102176 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I19 compound treatment 313800.0 -296000.0 -0.79 232500.0 -277000.0 -0.76 -1.0961 -0.9998 3069647 PK04_102177 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I20 compound treatment 641830.0 32400.0 0.09 230800.0 -279000.0 -0.77 -0.4798 -0.6231 3188890 PK04_102178 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I21 mock treatment 622480.0 13100.0 0.03 291730.0 -218000.0 -0.6 -0.3981 -0.6647 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I22 mock treatment 604870.0 -4540.0 -0.01 342880.0 -167000.0 -0.46 -0.3321 -0.7256 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I23 compound treatment 336040.0 -273000.0 -0.73 243000.0 -267000.0 -0.73 -1.0337 -1.0 3188891 PK04_102179 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 I24 compound treatment 288690.0 -321000.0 -0.86 234720.0 -275000.0 -0.75 -1.1392 -0.998 3069706 PK04_102180 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J01 compound treatment 606310.0 -3100.0 -0.01 322170.0 -187000.0 -0.51 -0.3695 -0.7184 3188892 PK04_102181 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J02 compound treatment 669890.0 60500.0 0.16 449800.0 -59700.0 -0.16 -0.0017 -0.0073 3069707 PK04_102182 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J03 compound treatment 439040.0 -170000.0 -0.46 581370.0 71900.0 0.2 -0.1823 -0.3675 3188893 PK04_102183 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J04 compound treatment 629180.0 19800.0 0.05 821470.0 312000.0 0.86 0.6429 0.7493 3069711 PK04_102184 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J05 mock treatment 234620.0 -375000.0 -1.0 223260.0 -286000.0 -0.79 -1.2636 -0.9928 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J06 mock treatment 410720.0 -199000.0 -0.53 329560.0 -180000.0 -0.49 -0.7246 -0.9994 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J07 compound treatment 390410.0 -219000.0 -0.58 317930.0 -192000.0 -0.53 -0.7855 -0.9986 3188894 PK04_102185 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J08 compound treatment 61920.0 -547000.0 -1.46 28440.0 -481000.0 -1.32 -1.9679 -0.9987 3069714 PK04_102186 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J09 compound treatment 328030.0 -281000.0 -0.75 228000.0 -282000.0 -0.77 -1.0779 -0.9999 3188895 PK04_102187 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J10 compound treatment 775430.0 166000.0 0.44 451690.0 -57800.0 -0.16 0.2013 0.4274 3069716 PK04_102188 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J11 compound treatment 244640.0 -365000.0 -0.97 231360.0 -278000.0 -0.76 -1.2289 -0.9927 3188896 PK04_102189 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J12 compound treatment 93940.0 -515000.0 -1.38 95630.0 -414000.0 -1.14 -1.777 -0.9955 3069744 PK04_102190 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J13 compound treatment 296960.0 -312000.0 -0.83 155200.0 -354000.0 -0.97 -1.2779 -0.9971 3188897 PK04_102191 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J14 compound treatment 252320.0 -357000.0 -0.95 558880.0 49400.0 0.14 -0.5786 -0.6006 3069746 PK04_102192 OCCOc1ccc(cc1)[C@@H](O)CC=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J15 compound treatment 571870.0 -37500.0 -0.1 444580.0 -64900.0 -0.18 -0.197 -0.963 3069749 PK04_102193 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J16 compound treatment 765350.0 156000.0 0.42 666660.0 157000.0 0.43 0.5996 0.9998 3188898 PK04_102194 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J17 compound treatment 420960.0 -188000.0 -0.5 476110.0 -33400.0 -0.09 -0.4208 -0.8224 3188899 PK04_102195 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J18 compound treatment 432000.0 -177000.0 -0.47 152480.0 -357000.0 -0.98 -1.0282 -0.9444 3069504 PK04_102196 O[C@H](CC=C)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J19 compound treatment 497380.0 -112000.0 -0.3 359260.0 -150000.0 -0.41 -0.5033 -0.9876 3188900 PK04_102197 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J20 compound treatment 340290.0 -269000.0 -0.72 245970.0 -264000.0 -0.72 -1.0199 -1.0 3069264 PK04_102198 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J21 mock treatment 761170.0 152000.0 0.41 796040.0 287000.0 0.79 0.8429 0.9525 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J22 mock treatment 629280.0 19900.0 0.05 391100.0 -118000.0 -0.33 -0.1923 -0.5839 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J23 compound treatment 586880.0 -22500.0 -0.06 330240.0 -179000.0 -0.49 -0.3906 -0.7877 3069786 PK04_102199 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 J24 compound treatment 386150.0 -223000.0 -0.6 442790.0 -66700.0 -0.18 -0.5512 -0.8836 3188901 PK04_102200 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K01 compound treatment 779210.0 170000.0 0.45 669190.0 160000.0 0.44 0.6307 0.9999 3069787 PK04_102201 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(CCO)nn2)/C=C/C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K02 compound treatment 352680.0 -257000.0 -0.69 393460.0 -116000.0 -0.32 -0.7102 -0.9392 3188902 PK04_102202 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K03 compound treatment 552480.0 -56900.0 -0.15 446450.0 -63100.0 -0.17 -0.2299 -0.9979 3188903 PK04_102203 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K04 compound treatment 344070.0 -265000.0 -0.71 285680.0 -224000.0 -0.61 -0.9357 -0.9975 3069790 PK04_102204 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K05 compound treatment 771060.0 162000.0 0.43 250440.0 -259000.0 -0.71 -0.1976 -0.2375 3188904 PK04_102205 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K06 compound treatment 158110.0 -451000.0 -1.21 462920.0 -46600.0 -0.13 -0.9428 -0.7778 3189012 PK04_102206 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K07 mock treatment 896640.0 287000.0 0.77 872830.0 363000.0 1.0 1.2478 0.9916 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K08 mock treatment 616050.0 6640.0 0.02 623370.0 114000.0 0.31 0.2336 0.746 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K09 compound treatment 883320.0 274000.0 0.73 382770.0 -127000.0 -0.35 0.2713 0.3349 3069821 PK04_102207 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K10 compound treatment 504590.0 -105000.0 -0.28 403120.0 -106000.0 -0.29 -0.4045 -0.9998 3189013 PK04_102208 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K11 compound treatment 241160.0 -368000.0 -0.98 325950.0 -184000.0 -0.5 -1.0519 -0.9517 3069825 PK04_102209 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K12 compound treatment 170570.0 -439000.0 -1.17 399440.0 -110000.0 -0.3 -1.0425 -0.8612 3189014 PK04_102210 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K13 compound treatment 439040.0 -170000.0 -0.46 253120.0 -256000.0 -0.7 -0.8195 -0.9777 3189015 PK04_102211 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K14 compound treatment 261630.0 -348000.0 -0.93 381780.0 -128000.0 -0.35 -0.9048 -0.9113 3069831 PK04_102212 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K15 mock treatment 897930.0 289000.0 0.77 359730.0 -150000.0 -0.41 0.2541 0.291 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K16 mock treatment 374720.0 -235000.0 -0.63 295890.0 -214000.0 -0.59 -0.858 -0.9994 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K17 compound treatment 458080.0 -151000.0 -0.4 287260.0 -222000.0 -0.61 -0.7173 -0.98 3189016 PK04_102213 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K18 compound treatment 246440.0 -363000.0 -0.97 204570.0 -305000.0 -0.84 -1.2775 -0.9973 3069867 PK04_102214 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K19 compound treatment 320640.0 -289000.0 -0.77 275700.0 -234000.0 -0.64 -0.9993 -0.9958 3189017 PK04_102215 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K20 compound treatment 257060.0 -352000.0 -0.94 227420.0 -282000.0 -0.77 -1.2131 -0.9953 3069873 PK04_102216 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K21 compound treatment 315710.0 -294000.0 -0.78 357760.0 -152000.0 -0.42 -0.8493 -0.9562 3189018 PK04_102217 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K22 compound treatment 382040.0 -227000.0 -0.61 334780.0 -175000.0 -0.48 -0.7686 -0.9932 3189019 PK04_102218 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K23 mock treatment 605760.0 -3650.0 -0.01 338730.0 -171000.0 -0.47 -0.3384 -0.7217 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 K24 mock treatment 878430.0 269000.0 0.72 219560.0 -290000.0 -0.8 -0.0548 -0.0511 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L01 compound treatment 737280.0 128000.0 0.34 508960.0 -551.0 0.0 0.2404 0.704 3069879 PK04_102219 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L02 compound treatment 631690.0 22300.0 0.06 737620.0 228000.0 0.63 0.4849 0.7708 3189020 PK04_102220 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L03 compound treatment 649850.0 40400.0 0.11 432670.0 -76800.0 -0.21 -0.0728 -0.3071 3189021 PK04_102221 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L04 compound treatment 761560.0 152000.0 0.41 439000.0 -70500.0 -0.19 0.1505 0.3343 3069907 PK04_102222 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L05 compound treatment 534690.0 -74700.0 -0.2 376850.0 -133000.0 -0.36 -0.3987 -0.9599 3189022 PK04_102223 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L06 compound treatment 508100.0 -101000.0 -0.27 418800.0 -90700.0 -0.25 -0.3674 -0.9991 3069909 PK04_102224 C[C@@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L07 mock treatment 840760.0 231000.0 0.62 541640.0 32100.0 0.09 0.4993 0.7999 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L08 mock treatment 897720.0 288000.0 0.77 467040.0 -42500.0 -0.12 0.4621 0.5933 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L09 compound treatment 262560.0 -347000.0 -0.93 249890.0 -260000.0 -0.71 -1.1591 -0.9916 3189023 PK04_102225 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L10 compound treatment 692610.0 83200.0 0.22 606350.0 96800.0 0.27 0.3451 0.996 3069912 PK04_102226 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L11 compound treatment 368000.0 -241000.0 -0.64 332960.0 -177000.0 -0.48 -0.7987 -0.9901 3189024 PK04_102227 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L12 compound treatment 812530.0 203000.0 0.54 659240.0 150000.0 0.41 0.6743 0.9906 3069746 PK04_102228 OCCOc1ccc(cc1)[C@@H](O)CC=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L13 compound treatment 259520.0 -350000.0 -0.93 306350.0 -203000.0 -0.56 -1.0552 -0.9696 3069917 PK04_102229 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L14 compound treatment 407590.0 -202000.0 -0.54 564020.0 54500.0 0.15 -0.2754 -0.4922 3069920 PK04_102230 O[C@@H](CC=C)c1ccc(O)c(F)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L15 mock treatment 385920.0 -223000.0 -0.6 233760.0 -276000.0 -0.76 -0.9574 -0.9931 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L16 mock treatment 884450.0 275000.0 0.73 338640.0 -171000.0 -0.47 0.1877 0.2154 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L17 compound treatment 805020.0 196000.0 0.52 390400.0 -119000.0 -0.33 0.1382 0.2242 3189025 PK04_102231 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L18 compound treatment 435520.0 -174000.0 -0.46 368080.0 -141000.0 -0.39 -0.603 -0.996 3069953 PK04_102232 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L19 compound treatment 489150.0 -120000.0 -0.32 223970.0 -286000.0 -0.78 -0.7815 -0.9224 3189026 PK04_102233 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L20 compound treatment 799200.0 190000.0 0.51 805920.0 296000.0 0.81 0.9339 0.9741 3069956 PK04_102234 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L21 compound treatment 373330.0 -236000.0 -0.63 258250.0 -251000.0 -0.69 -0.9337 -0.999 3189027 PK04_102235 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L22 compound treatment 678170.0 68800.0 0.18 523210.0 13700.0 0.04 0.1565 0.8346 3069961 PK04_102236 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L23 mock treatment 762740.0 153000.0 0.41 462980.0 -46500.0 -0.13 0.1993 0.4645 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 L24 mock treatment 846400.0 237000.0 0.63 442560.0 -67000.0 -0.18 0.3176 0.4819 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M01 compound treatment 530170.0 -79200.0 -0.21 707600.0 198000.0 0.54 0.2349 0.4025 3069962 PK04_102237 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M02 compound treatment 500960.0 -108000.0 -0.29 349340.0 -160000.0 -0.44 -0.5158 -0.9795 3188628 PK04_102238 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M03 compound treatment 342010.0 -267000.0 -0.71 343840.0 -166000.0 -0.45 -0.8266 -0.9763 3189028 PK04_102239 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M04 compound treatment 273600.0 -336000.0 -0.9 375410.0 -134000.0 -0.37 -0.8946 -0.9226 3189141 PK04_102240 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M05 compound treatment 433540.0 -176000.0 -0.47 233410.0 -276000.0 -0.76 -0.8682 -0.9735 3069277 PK04_102241 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M06 compound treatment 348640.0 -261000.0 -0.7 288890.0 -221000.0 -0.61 -0.9208 -0.9976 3189142 PK04_102242 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M07 compound treatment 207610.0 -402000.0 -1.07 209920.0 -300000.0 -0.82 -1.3405 -0.9914 3189143 PK04_102243 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M08 compound treatment 276440.0 -333000.0 -0.89 406680.0 -103000.0 -0.28 -0.8285 -0.8879 3069284 PK04_102244 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M09 mock treatment 666120.0 56700.0 0.15 819840.0 310000.0 0.85 0.7096 0.82 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M10 mock treatment 833600.0 224000.0 0.6 833630.0 324000.0 0.89 1.0526 0.9814 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M11 compound treatment 821040.0 212000.0 0.57 298400.0 -211000.0 -0.58 -0.0101 -0.0125 3189144 PK04_102245 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M12 compound treatment 532860.0 -76500.0 -0.2 230630.0 -279000.0 -0.77 -0.686 -0.8656 3189145 PK04_102246 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M13 mock treatment 842530.0 233000.0 0.62 497970.0 -11500.0 -0.03 0.4179 0.6703 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M14 mock treatment 678250.0 68800.0 0.18 671680.0 162000.0 0.45 0.4448 0.9235 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M15 compound treatment 342640.0 -267000.0 -0.71 317450.0 -192000.0 -0.53 -0.8767 -0.989 3189146 PK04_102247 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M16 compound treatment 278080.0 -331000.0 -0.88 475940.0 -33600.0 -0.09 -0.6909 -0.7765 3189147 PK04_102248 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M17 compound treatment 350150.0 -259000.0 -0.69 256160.0 -253000.0 -0.7 -0.9815 -1.0 3069327 PK04_102249 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M18 compound treatment 596020.0 -13400.0 -0.04 200860.0 -309000.0 -0.85 -0.6245 -0.7363 3189148 PK04_102250 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M19 compound treatment 882350.0 273000.0 0.73 617720.0 108000.0 0.3 0.7256 0.9217 3069330 PK04_102251 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M20 compound treatment 463150.0 -146000.0 -0.39 243250.0 -266000.0 -0.73 -0.7931 -0.9569 3189149 PK04_102252 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M21 compound treatment 318240.0 -291000.0 -0.78 305450.0 -204000.0 -0.56 -0.9461 -0.987 3189150 PK04_102253 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M22 compound treatment 338840.0 -271000.0 -0.72 592550.0 83000.0 0.23 -0.3498 -0.4616 3189151 PK04_102254 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M23 compound treatment 481280.0 -128000.0 -0.34 269400.0 -240000.0 -0.66 -0.7081 -0.9534 3189152 PK04_102255 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 M24 compound treatment 309600.0 -300000.0 -0.8 244840.0 -265000.0 -0.73 -1.0801 -0.9988 3069375 PK04_102256 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N01 compound treatment 343920.0 -265000.0 -0.71 316200.0 -193000.0 -0.53 -0.8767 -0.9898 3189153 PK04_102257 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N02 compound treatment 753640.0 144000.0 0.39 740160.0 231000.0 0.63 0.7202 0.9716 3069379 PK04_102258 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N03 compound treatment 666950.0 57500.0 0.15 785650.0 276000.0 0.76 0.6447 0.8335 3189154 PK04_102259 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N04 compound treatment 821880.0 212000.0 0.57 792320.0 283000.0 0.78 0.9503 0.9881 3069716 PK04_102260 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N05 compound treatment 585720.0 -23700.0 -0.06 729870.0 220000.0 0.6 0.383 0.6297 3069403 PK04_102261 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N06 compound treatment 368020.0 -241000.0 -0.64 325190.0 -184000.0 -0.51 -0.8137 -0.9928 3069417 PK04_102262 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N07 compound treatment 569930.0 -39500.0 -0.11 791200.0 282000.0 0.77 0.4723 0.6051 3189155 PK04_102263 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N08 compound treatment 729960.0 121000.0 0.32 692990.0 183000.0 0.5 0.5839 0.9766 3069421 PK04_102264 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N09 mock treatment 915600.0 306000.0 0.82 756250.0 247000.0 0.68 1.0573 0.9956 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N10 mock treatment 504340.0 -105000.0 -0.28 753340.0 244000.0 0.67 0.2749 0.3787 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N11 compound treatment 587770.0 -21600.0 -0.06 366890.0 -143000.0 -0.39 -0.3177 -0.8028 3189156 PK04_102265 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N12 compound treatment 569250.0 -40200.0 -0.11 503790.0 -5720.0 -0.02 -0.087 -0.8021 3069424 PK04_102266 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N13 mock treatment 407130.0 -202000.0 -0.54 671310.0 162000.0 0.44 -0.0679 -0.0971 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N14 mock treatment 510370.0 -99000.0 -0.26 530840.0 21300.0 0.06 -0.1456 -0.5376 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N15 compound treatment 620750.0 11300.0 0.03 560520.0 51000.0 0.14 0.1204 0.8406 3189268 PK04_102267 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N16 compound treatment 791580.0 182000.0 0.49 602590.0 93100.0 0.26 0.5248 0.9548 3069404 PK04_102268 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N17 compound treatment 746400.0 137000.0 0.37 530320.0 20800.0 0.06 0.2991 0.8077 3069428 PK04_102269 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N18 compound treatment 876410.0 267000.0 0.71 775360.0 266000.0 0.73 1.0204 0.9999 3189269 PK04_102270 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N19 compound treatment 536550.0 -72900.0 -0.19 452830.0 -56700.0 -0.16 -0.2476 -0.9939 3070277 PK04_102271 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N20 compound treatment 854480.0 245000.0 0.65 449870.0 -59600.0 -0.16 0.3471 0.5144 3069270 PK04_102272 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N21 compound treatment 466240.0 -143000.0 -0.38 416750.0 -92800.0 -0.25 -0.4505 -0.9805 3070278 PK04_102273 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N22 compound treatment 270600.0 -339000.0 -0.9 306650.0 -203000.0 -0.56 -1.0337 -0.9728 3070279 PK04_102274 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N23 compound treatment 692420.0 83000.0 0.22 396010.0 -114000.0 -0.31 -0.0636 -0.1662 3070280 PK04_102275 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 N24 compound treatment 757830.0 148000.0 0.4 382500.0 -127000.0 -0.35 0.0337 0.0639 3189270 PK04_102276 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O01 compound treatment 550000.0 -59400.0 -0.16 728180.0 219000.0 0.6 0.3123 0.5029 3189271 PK04_102277 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O02 compound treatment 269760.0 -340000.0 -0.91 314660.0 -195000.0 -0.53 -1.0198 -0.9683 3070281 PK04_102278 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O03 compound treatment 607430.0 -1980.0 -0.01 673500.0 164000.0 0.45 0.3146 0.6988 3189272 PK04_102279 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O04 compound treatment 233050.0 -376000.0 -1.01 260730.0 -249000.0 -0.68 -1.1938 -0.9823 3189273 PK04_102280 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O05 compound treatment 271690.0 -338000.0 -0.9 295280.0 -214000.0 -0.59 -1.0537 -0.9785 3070282 PK04_102281 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O06 compound treatment 199790.0 -410000.0 -1.09 242640.0 -267000.0 -0.73 -1.2917 -0.981 3189274 PK04_102282 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O07 compound treatment 411110.0 -198000.0 -0.53 257780.0 -252000.0 -0.69 -0.8632 -0.9914 3070283 PK04_102283 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O08 compound treatment 223210.0 -386000.0 -1.03 247240.0 -262000.0 -0.72 -1.2386 -0.9846 3189275 PK04_102284 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O09 compound treatment 553620.0 -55800.0 -0.15 264990.0 -245000.0 -0.67 -0.5801 -0.8435 3189276 PK04_102285 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O10 compound treatment 427260.0 -182000.0 -0.49 215520.0 -294000.0 -0.81 -0.9147 -0.9706 3070284 PK04_102286 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O11 mock treatment 583430.0 -26000.0 -0.07 566400.0 56900.0 0.16 0.0614 0.3591 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O12 mock treatment 311220.0 -298000.0 -0.8 348090.0 -161000.0 -0.44 -0.8766 -0.9617 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O13 compound treatment 412730.0 -197000.0 -0.53 225280.0 -284000.0 -0.78 -0.9232 -0.9815 3189277 PK04_102287 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4ccccc43 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O14 compound treatment 271490.0 -338000.0 -0.9 424890.0 -84600.0 -0.23 -0.8025 -0.861 3189278 PK04_102288 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O15 compound treatment 184690.0 -425000.0 -1.13 331840.0 -178000.0 -0.49 -1.1471 -0.9289 3070285 PK04_102289 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O16 compound treatment 280530.0 -329000.0 -0.88 341800.0 -168000.0 -0.46 -0.9467 -0.9546 3189279 PK04_102290 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O17 compound treatment 450910.0 -158000.0 -0.42 217460.0 -292000.0 -0.8 -0.8663 -0.9555 3070286 PK04_102291 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O18 compound treatment 495520.0 -114000.0 -0.3 250520.0 -259000.0 -0.71 -0.7179 -0.9282 3189280 PK04_102292 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O19 compound treatment 373920.0 -235000.0 -0.63 227730.0 -282000.0 -0.77 -0.9918 -0.9947 3189281 PK04_102293 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O20 compound treatment 240910.0 -368000.0 -0.98 207780.0 -302000.0 -0.83 -1.2817 -0.9963 3070287 PK04_102294 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O21 compound treatment 234020.0 -375000.0 -1.0 203040.0 -306000.0 -0.84 -1.3039 -0.9962 3189282 PK04_102295 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O22 compound treatment 286260.0 -323000.0 -0.86 315070.0 -194000.0 -0.53 -0.9878 -0.9733 3070288 PK04_102296 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O23 compound treatment 292610.0 -317000.0 -0.85 236710.0 -273000.0 -0.75 -1.1279 -0.9981 3189283 PK04_102297 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 O24 compound treatment 169770.0 -440000.0 -1.17 148970.0 -361000.0 -0.99 -1.5303 -0.9964 3189284 PK04_102298 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P01 compound treatment 202840.0 -407000.0 -1.09 300000.0 -210000.0 -0.58 -1.1746 -0.9558 3070289 PK04_102299 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P02 compound treatment 531570.0 -77800.0 -0.21 321620.0 -188000.0 -0.52 -0.5118 -0.9202 3069953 PK04_102300 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P03 compound treatment 155870.0 -454000.0 -1.21 282780.0 -227000.0 -0.62 -1.2967 -0.9521 3189285 PK04_102301 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P04 compound treatment 273510.0 -336000.0 -0.9 236690.0 -273000.0 -0.75 -1.164 -0.996 3070290 PK04_102302 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P05 compound treatment 150100.0 -459000.0 -1.23 172670.0 -337000.0 -0.92 -1.5214 -0.9903 3189394 PK04_102303 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P06 compound treatment 244030.0 -365000.0 -0.98 289120.0 -220000.0 -0.61 -1.1179 -0.9736 3069907 PK04_102304 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P07 compound treatment 279480.0 -330000.0 -0.88 293170.0 -216000.0 -0.59 -1.0431 -0.9816 3189395 PK04_102305 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P08 compound treatment 522880.0 -86500.0 -0.23 456390.0 -53100.0 -0.15 -0.2666 -0.9754 3069314 PK04_102306 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P09 compound treatment 234850.0 -375000.0 -1.0 215800.0 -294000.0 -0.81 -1.2776 -0.9943 3070291 PK04_102307 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P10 compound treatment 281510.0 -328000.0 -0.88 227240.0 -282000.0 -0.77 -1.1673 -0.9981 3189396 PK04_102308 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P11 mock treatment 347840.0 -262000.0 -0.7 306400.0 -203000.0 -0.56 -0.8883 -0.9938 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P12 mock treatment 491380.0 -118000.0 -0.32 297090.0 -212000.0 -0.58 -0.6353 -0.9583 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P13 compound treatment 339650.0 -270000.0 -0.72 235910.0 -274000.0 -0.75 -1.0406 -0.9998 3189397 PK04_102309 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P14 compound treatment 367220.0 -242000.0 -0.65 310930.0 -199000.0 -0.55 -0.8429 -0.9964 3070292 PK04_102310 OCCOc1ccc(cc1)[C@H](O)CC=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P15 compound treatment 233850.0 -376000.0 -1.0 234770.0 -275000.0 -0.75 -1.2427 -0.9901 3070293 PK04_102311 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P16 compound treatment 236160.0 -373000.0 -1.0 220160.0 -289000.0 -0.79 -1.2667 -0.9937 3070292 PK04_102312 OCCOc1ccc(cc1)[C@H](O)CC=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P17 compound treatment 233330.0 -376000.0 -1.0 291610.0 -218000.0 -0.6 -1.1333 -0.9693 3189398 PK04_102313 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P18 compound treatment 248970.0 -360000.0 -0.96 183900.0 -326000.0 -0.89 -1.3129 -0.9993 3070294 PK04_102314 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P19 compound treatment 273570.0 -336000.0 -0.9 283590.0 -226000.0 -0.62 -1.0729 -0.9838 3189399 PK04_102315 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P20 compound treatment 201060.0 -408000.0 -1.09 185920.0 -324000.0 -0.89 -1.3994 -0.9948 3070290 PK04_102316 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P21 compound treatment 144960.0 -464000.0 -1.24 119360.0 -390000.0 -1.07 -1.6346 -0.9973 3189400 PK04_102317 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P22 compound treatment 334240.0 -275000.0 -0.73 255370.0 -254000.0 -0.7 -1.0131 -0.9997 3070295 PK04_102318 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P23 compound treatment 263070.0 -346000.0 -0.93 272960.0 -237000.0 -0.65 -1.1133 -0.985 3189401 PK04_102319 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2102 P24 compound treatment 210610.0 -399000.0 -1.07 306720.0 -203000.0 -0.56 -1.1469 -0.9542 3414053 PK04_102320 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A01 compound treatment 283070.0 -254000.0 -0.68 690080.0 223000.0 0.61 -0.0471 -0.0515 3221174 PK04_130001 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N[C@@H]3[C@H](O)Cc4ccccc34 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A02 compound treatment 805300.0 268000.0 0.72 329630.0 -137000.0 -0.38 0.2395 0.2959 3211805 PK04_130002 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A03 compound treatment 812840.0 276000.0 0.74 284130.0 -183000.0 -0.5 0.1654 0.1856 3221177 PK04_130003 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccccc4F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A04 compound treatment 452270.0 -85000.0 -0.23 754290.0 287000.0 0.79 0.3971 0.484 3080218 PK04_130004 OCCC[C@@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A05 compound treatment 523210.0 -14000.0 -0.04 747960.0 281000.0 0.77 0.5188 0.672 3221180 PK04_130005 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A06 compound treatment 340090.0 -197000.0 -0.53 729030.0 262000.0 0.72 0.1362 0.1528 3211801 PK04_130006 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A07 compound treatment 719420.0 182000.0 0.49 399480.0 -67600.0 -0.19 0.2129 0.4088 3221183 PK04_130007 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A08 compound treatment 400180.0 -137000.0 -0.37 217400.0 -250000.0 -0.69 -0.7435 -0.9568 3080220 PK04_130008 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A09 compound treatment 335480.0 -202000.0 -0.54 317630.0 -149000.0 -0.41 -0.6711 -0.9909 3221185 PK04_130009 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3coc4ccccc4c3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A10 compound treatment 617980.0 80700.0 0.22 601180.0 134000.0 0.37 0.4129 0.9675 3080222 PK04_130010 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A11 compound treatment 470350.0 -66900.0 -0.18 343910.0 -123000.0 -0.34 -0.3654 -0.9555 3221188 PK04_130011 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3coc4ccccc4c3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A12 compound treatment 252730.0 -285000.0 -0.76 510440.0 43400.0 0.12 -0.4531 -0.5891 3211814 PK04_130012 C[C@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A13 mock treatment 723280.0 186000.0 0.5 325640.0 -141000.0 -0.39 0.0768 0.1218 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A14 mock treatment 402720.0 -135000.0 -0.36 388870.0 -78200.0 -0.21 -0.4059 -0.9697 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A15 compound treatment 289570.0 -248000.0 -0.66 552650.0 85600.0 0.23 -0.3016 -0.4296 3221191 PK04_130013 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A16 compound treatment 751940.0 215000.0 0.57 577760.0 111000.0 0.3 0.6204 0.9559 3080206 PK04_130014 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A17 compound treatment 535440.0 -1800.0 0.0 483200.0 16100.0 0.04 0.0279 0.6269 3221194 PK04_130015 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N[C@@H]4[C@H](O)Cc5ccccc45 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A18 compound treatment 544680.0 7440.0 0.02 748360.0 281000.0 0.77 0.5601 0.7251 3211690 PK04_130016 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A19 compound treatment 308290.0 -229000.0 -0.61 475040.0 7970.0 0.02 -0.4169 -0.6814 3221197 PK04_130017 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3coc4ccccc4c3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A20 compound treatment 554110.0 16900.0 0.05 456640.0 -10400.0 -0.03 0.0116 0.2179 3189020 PK04_130018 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A21 compound treatment 213380.0 -324000.0 -0.87 224260.0 -243000.0 -0.67 -1.083 -0.9917 2019329 PK04_130019 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCCCCCC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A22 compound treatment 741600.0 204000.0 0.55 836530.0 369000.0 1.01 1.1032 0.9578 3080190 PK04_130020 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A23 compound treatment 241960.0 -295000.0 -0.79 306630.0 -160000.0 -0.44 -0.8691 -0.9621 3221200 PK04_130021 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 A24 compound treatment 714730.0 177000.0 0.47 467490.0 425.0 0.0 0.3361 0.7088 3211695 PK04_130022 CO[C@@H](CCO)[C@@H](O)c1ccc(O)c(F)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B01 compound treatment 740590.0 203000.0 0.54 686900.0 220000.0 0.6 0.8108 0.9986 3176327 PK04_130023 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B02 compound treatment 708710.0 171000.0 0.46 482080.0 15000.0 0.04 0.353 0.7676 3221203 PK04_130024 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B03 compound treatment 727720.0 190000.0 0.51 745880.0 279000.0 0.77 0.901 0.9803 3052745 PK04_130025 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B04 compound treatment 886610.0 349000.0 0.93 804000.0 337000.0 0.93 1.3139 1.0 3221205 PK04_130026 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B05 compound treatment 569700.0 32500.0 0.09 687770.0 221000.0 0.61 0.4898 0.8001 3176512 PK04_130027 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B06 compound treatment 652760.0 116000.0 0.31 639890.0 173000.0 0.47 0.5537 0.9783 3221207 PK04_130028 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B07 compound treatment 393410.0 -144000.0 -0.38 367810.0 -99300.0 -0.27 -0.4643 -0.9858 3176123 PK04_130029 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B08 compound treatment 551450.0 14200.0 0.04 322350.0 -145000.0 -0.4 -0.2541 -0.6366 3221209 PK04_130030 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B09 compound treatment 774110.0 237000.0 0.63 787270.0 320000.0 0.88 1.069 0.987 3052645 PK04_130031 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B10 compound treatment 756700.0 219000.0 0.59 449250.0 -17800.0 -0.05 0.3799 0.6459 3221211 PK04_130032 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B11 compound treatment 750560.0 213000.0 0.57 266880.0 -200000.0 -0.55 0.0143 0.018 3052831 PK04_130033 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B12 compound treatment 453780.0 -83500.0 -0.22 450880.0 -16200.0 -0.04 -0.189 -0.8317 3221213 PK04_130034 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B13 mock treatment 312170.0 -225000.0 -0.6 366940.0 -100000.0 -0.27 -0.6194 -0.9371 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B14 mock treatment 826820.0 290000.0 0.77 576840.0 110000.0 0.3 0.76 0.9156 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B15 compound treatment 281540.0 -256000.0 -0.68 667690.0 201000.0 0.55 -0.0934 -0.1065 3176778 PK04_130035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B16 compound treatment 644960.0 108000.0 0.29 393680.0 -73400.0 -0.2 0.061 0.1736 3221214 PK04_130036 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B17 compound treatment 277440.0 -260000.0 -0.69 783790.0 317000.0 0.87 0.1242 0.1116 3176195 PK04_130037 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B18 compound treatment 629020.0 91800.0 0.25 683770.0 217000.0 0.59 0.594 0.9232 3221216 PK04_130038 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B19 compound treatment 627420.0 90200.0 0.24 346830.0 -120000.0 -0.33 -0.0631 -0.1544 3052584 PK04_130039 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B20 compound treatment 625250.0 88000.0 0.24 649370.0 182000.0 0.5 0.5201 0.9406 3221218 PK04_130040 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B21 compound treatment 643100.0 106000.0 0.28 542430.0 75400.0 0.21 0.3463 0.9882 3176736 PK04_130041 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B22 compound treatment 417180.0 -120000.0 -0.32 313500.0 -154000.0 -0.42 -0.5249 -0.9909 3221220 PK04_130042 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B23 compound treatment 807300.0 270000.0 0.72 722470.0 255000.0 0.7 1.0059 0.9999 3052927 PK04_130043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 B24 compound treatment 551230.0 14000.0 0.04 341280.0 -126000.0 -0.35 -0.2178 -0.6269 3221222 PK04_130044 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C01 compound treatment 532480.0 -4760.0 -0.01 633250.0 166000.0 0.46 0.3136 0.6872 3221224 PK04_130045 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccc(Cl)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C02 compound treatment 391680.0 -146000.0 -0.39 582880.0 116000.0 0.32 -0.0501 -0.0997 3211914 PK04_130046 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C03 compound treatment 732260.0 195000.0 0.52 695200.0 228000.0 0.63 0.8112 0.9958 3221227 PK04_130047 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C04 compound treatment 588210.0 51000.0 0.14 477940.0 10900.0 0.03 0.1174 0.8422 3211809 PK04_130048 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C05 compound treatment 685680.0 148000.0 0.4 446440.0 -20600.0 -0.06 0.2403 0.6 2019446 PK04_130049 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C06 compound treatment 616580.0 79300.0 0.21 537730.0 70700.0 0.19 0.287 0.999 3069417 PK04_130050 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C07 compound treatment 706880.0 170000.0 0.45 321220.0 -146000.0 -0.4 0.0373 0.0616 3221230 PK04_130051 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccc(O)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C08 compound treatment 701280.0 164000.0 0.44 511710.0 44600.0 0.12 0.3965 0.8715 3080227 PK04_130052 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C09 compound treatment 484980.0 -52300.0 -0.14 531600.0 64500.0 0.18 0.0266 0.1179 3221232 PK04_130053 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C10 compound treatment 629060.0 91800.0 0.25 575520.0 108000.0 0.3 0.384 0.9954 3080226 PK04_130054 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C11 mock treatment 702240.0 165000.0 0.44 369410.0 -97700.0 -0.27 0.1221 0.2366 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C12 mock treatment 539700.0 2460.0 0.01 654520.0 187000.0 0.51 0.3686 0.7161 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C13 compound treatment 580420.0 43200.0 0.12 504750.0 37700.0 0.1 0.1547 0.9985 3221235 PK04_130055 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCCCCCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C14 compound treatment 355630.0 -182000.0 -0.49 279280.0 -188000.0 -0.52 -0.7075 -0.9995 3080272 PK04_130056 OCCC[C@H](O)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C15 mock treatment 476480.0 -60800.0 -0.16 204060.0 -263000.0 -0.72 -0.6253 -0.8449 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C16 mock treatment 339950.0 -197000.0 -0.53 295280.0 -172000.0 -0.47 -0.7061 -0.9985 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C17 compound treatment 449920.0 -87300.0 -0.23 302530.0 -165000.0 -0.45 -0.4843 -0.9527 3221238 PK04_130057 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccc(O)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C18 compound treatment 207230.0 -330000.0 -0.88 312890.0 -154000.0 -0.42 -0.9226 -0.9435 3080228 PK04_130058 OCCC[C@@H](O)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C19 compound treatment 260060.0 -277000.0 -0.74 419940.0 -47100.0 -0.13 -0.615 -0.8183 2019457 PK04_130059 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3coc4ccccc4c3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C20 compound treatment 637510.0 100000.0 0.27 464560.0 -2510.0 -0.01 0.1845 0.6887 3080205 PK04_130060 OCCC[C@@H](O)c1ccc(O)c(F)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C21 compound treatment 639490.0 102000.0 0.27 397940.0 -69100.0 -0.19 0.0589 0.1772 3221241 PK04_130061 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4cccs4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C22 compound treatment 714250.0 177000.0 0.47 353570.0 -113000.0 -0.31 0.114 0.2013 3211908 PK04_130062 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C23 compound treatment 684960.0 148000.0 0.39 389020.0 -78000.0 -0.21 0.1275 0.284 2019323 PK04_130063 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 C24 compound treatment 610750.0 73500.0 0.2 236690.0 -230000.0 -0.63 -0.3084 -0.4657 3211812 PK04_130064 C[C@@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D01 compound treatment 779840.0 243000.0 0.65 530990.0 63900.0 0.18 0.5823 0.8674 3175965 PK04_130065 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D02 compound treatment 250500.0 -287000.0 -0.77 643680.0 177000.0 0.48 -0.1987 -0.2192 3221243 PK04_130066 COc1cc2c3N(C(=O)[C@@]42O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)C(C)(C)C=C(C)c3c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D03 compound treatment 808270.0 271000.0 0.72 404170.0 -62900.0 -0.17 0.3898 0.5238 3176379 PK04_130067 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D04 compound treatment 358450.0 -179000.0 -0.48 411680.0 -55400.0 -0.15 -0.4452 -0.8883 3221245 PK04_130068 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D05 compound treatment 669550.0 132000.0 0.35 510570.0 43500.0 0.12 0.3344 0.8963 3052839 PK04_130069 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D06 compound treatment 412800.0 -124000.0 -0.33 262680.0 -204000.0 -0.56 -0.6318 -0.9688 3221246 PK04_130070 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D07 compound treatment 590270.0 53000.0 0.14 452690.0 -14400.0 -0.04 0.0723 0.4914 3176048 PK04_130071 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D08 compound treatment 690190.0 153000.0 0.41 257380.0 -210000.0 -0.58 -0.1182 -0.1674 3221248 PK04_130072 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D09 compound treatment 584710.0 47500.0 0.13 591140.0 124000.0 0.34 0.3305 0.9094 3175970 PK04_130073 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D10 compound treatment 726880.0 190000.0 0.51 317200.0 -150000.0 -0.41 0.0672 0.103 3221250 PK04_130074 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D11 mock treatment 609890.0 72700.0 0.19 582750.0 116000.0 0.32 0.3618 0.9721 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D12 mock treatment 663930.0 127000.0 0.34 778610.0 312000.0 0.86 0.8441 0.9177 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D13 compound treatment 756160.0 219000.0 0.58 393960.0 -73100.0 -0.2 0.2716 0.4392 3176675 PK04_130075 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D14 compound treatment 544050.0 6810.0 0.02 640350.0 173000.0 0.48 0.3493 0.7336 3221251 PK04_130076 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D15 mock treatment 279090.0 -258000.0 -0.69 268990.0 -198000.0 -0.54 -0.8721 -0.9931 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D16 mock treatment 414800.0 -122000.0 -0.33 402370.0 -64700.0 -0.18 -0.3568 -0.9589 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D17 compound treatment 508920.0 -28300.0 -0.08 521400.0 54300.0 0.15 0.052 0.3109 3052531 PK04_130077 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D18 compound treatment 553920.0 16700.0 0.04 404420.0 -62600.0 -0.17 -0.0901 -0.5071 3221253 PK04_130078 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D19 compound treatment 584500.0 47300.0 0.13 608020.0 141000.0 0.39 0.3629 0.8915 3052793 PK04_130079 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D20 compound treatment 402720.0 -135000.0 -0.36 582080.0 115000.0 0.32 -0.0308 -0.0643 3221255 PK04_130080 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D21 compound treatment 712400.0 175000.0 0.47 282290.0 -185000.0 -0.51 -0.0279 -0.0404 3052828 PK04_130081 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D22 compound treatment 722490.0 185000.0 0.49 413640.0 -53400.0 -0.15 0.2462 0.477 3221256 PK04_130082 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D23 compound treatment 665050.0 128000.0 0.34 444390.0 -22700.0 -0.06 0.1974 0.5688 3052592 PK04_130083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 D24 compound treatment 370780.0 -166000.0 -0.44 338780.0 -128000.0 -0.35 -0.5634 -0.9933 3221257 PK04_130084 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E01 mock treatment 827870.0 291000.0 0.78 583040.0 116000.0 0.32 0.7741 0.9225 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E02 mock treatment 778510.0 241000.0 0.64 755200.0 288000.0 0.79 1.015 0.9948 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E03 compound treatment 694260.0 157000.0 0.42 421160.0 -45900.0 -0.13 0.2075 0.4737 2019322 PK04_130085 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3N 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E04 compound treatment 676800.0 140000.0 0.37 654790.0 188000.0 0.52 0.628 0.9874 3080210 PK04_130086 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E05 compound treatment 477050.0 -60200.0 -0.16 452850.0 -14200.0 -0.04 -0.1413 -0.854 3221259 PK04_130087 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E06 compound treatment 473880.0 -63400.0 -0.17 662640.0 196000.0 0.54 0.26 0.4619 3211802 PK04_130088 OCCC[C@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E07 compound treatment 588720.0 51500.0 0.14 727520.0 260000.0 0.72 0.6029 0.8279 3221261 PK04_130089 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccc(Cl)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E08 compound treatment 586930.0 49700.0 0.13 584170.0 117000.0 0.32 0.3212 0.9234 3080219 PK04_130090 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E09 mock treatment 804990.0 268000.0 0.72 202010.0 -265000.0 -0.73 -0.0089 -0.0087 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E10 mock treatment 545940.0 8700.0 0.02 567360.0 100000.0 0.28 0.2111 0.7641 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E11 compound treatment 622140.0 84900.0 0.23 461990.0 -5080.0 -0.01 0.1505 0.6624 3221264 PK04_130091 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cc(=O)n(c3ccccc3)n2C)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E12 compound treatment 464830.0 -72400.0 -0.19 206300.0 -261000.0 -0.72 -0.643 -0.867 3069920 PK04_130092 O[C@@H](CC=C)c1ccc(O)c(F)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E13 compound treatment 791750.0 255000.0 0.68 413600.0 -53500.0 -0.15 0.3769 0.5419 3221266 PK04_130093 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4N 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E14 compound treatment 577020.0 39800.0 0.11 300830.0 -166000.0 -0.46 -0.2476 -0.5283 3211678 PK04_130094 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E15 compound treatment 428600.0 -109000.0 -0.29 401790.0 -65300.0 -0.18 -0.3319 -0.9732 3221269 PK04_130095 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCOCCOCCOCCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E16 compound treatment 221470.0 -316000.0 -0.84 184350.0 -283000.0 -0.78 -1.1452 -0.9991 3211906 PK04_130096 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E17 mock treatment 656320.0 119000.0 0.32 336650.0 -130000.0 -0.36 -0.0283 -0.059 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E18 mock treatment 246190.0 -291000.0 -0.78 261480.0 -206000.0 -0.56 -0.9488 -0.9876 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E19 compound treatment 344190.0 -193000.0 -0.52 232260.0 -235000.0 -0.64 -0.8204 -0.9939 2019458 PK04_130097 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3coc4ccccc4c3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E20 compound treatment 453220.0 -84000.0 -0.22 688680.0 222000.0 0.61 0.2715 0.4187 3211804 PK04_130098 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E21 compound treatment 355420.0 -182000.0 -0.49 244400.0 -223000.0 -0.61 -0.7757 -0.9935 3221271 PK04_130099 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E22 compound treatment 722890.0 186000.0 0.5 251880.0 -215000.0 -0.59 -0.0671 -0.087 3211680 PK04_130100 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E23 compound treatment 597380.0 60100.0 0.16 212880.0 -254000.0 -0.7 -0.3799 -0.5305 2019464 PK04_130101 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3coc4ccccc4c3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 E24 compound treatment 402260.0 -135000.0 -0.36 188500.0 -279000.0 -0.76 -0.7957 -0.9411 3211909 PK04_130102 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F01 mock treatment 819170.0 282000.0 0.75 769930.0 303000.0 0.83 1.1204 0.9988 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F02 mock treatment 495460.0 -41800.0 -0.11 467120.0 54.9 0.0 -0.0788 -0.7062 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F03 compound treatment 533300.0 -3940.0 -0.01 331570.0 -135000.0 -0.37 -0.2705 -0.7268 3176785 PK04_130103 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F04 compound treatment 573600.0 36400.0 0.1 506490.0 39400.0 0.11 0.1452 0.9985 3221273 PK04_130104 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F05 compound treatment 749360.0 212000.0 0.57 342450.0 -125000.0 -0.34 0.1587 0.2398 3176500 PK04_130105 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F06 compound treatment 346110.0 -191000.0 -0.51 766950.0 300000.0 0.82 0.2212 0.2283 3221274 PK04_130106 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F07 compound treatment 782140.0 245000.0 0.65 561130.0 94100.0 0.26 0.6452 0.9174 3052886 PK04_130107 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F08 compound treatment 762170.0 225000.0 0.6 578170.0 111000.0 0.31 0.6405 0.9506 3221275 PK04_130108 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F09 mock treatment 623270.0 86000.0 0.23 689920.0 223000.0 0.61 0.5951 0.9106 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F10 mock treatment 500480.0 -36800.0 -0.1 332330.0 -135000.0 -0.37 -0.331 -0.8648 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F11 compound treatment 364860.0 -172000.0 -0.46 337830.0 -129000.0 -0.35 -0.5764 -0.9917 3052654 PK04_130109 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F12 compound treatment 661920.0 125000.0 0.33 307200.0 -160000.0 -0.44 -0.0749 -0.1359 3221277 PK04_130110 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F13 compound treatment 784710.0 247000.0 0.66 219940.0 -247000.0 -0.68 -0.0123 -0.013 3052647 PK04_130111 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F14 compound treatment 609540.0 72300.0 0.19 770880.0 304000.0 0.83 0.7264 0.8484 3221279 PK04_130112 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F15 compound treatment 728430.0 191000.0 0.51 343760.0 -123000.0 -0.34 0.1217 0.1987 3176113 PK04_130113 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F16 compound treatment 729530.0 192000.0 0.51 515750.0 48700.0 0.13 0.4577 0.8624 3221280 PK04_130114 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F17 mock treatment 293600.0 -244000.0 -0.65 258560.0 -209000.0 -0.57 -0.8649 -0.998 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F18 mock treatment 303760.0 -233000.0 -0.62 735840.0 269000.0 0.74 0.0808 0.0837 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F19 compound treatment 302520.0 -235000.0 -0.63 307330.0 -160000.0 -0.44 -0.7534 -0.9847 3052888 PK04_130115 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F20 compound treatment 288720.0 -249000.0 -0.66 337280.0 -130000.0 -0.36 -0.7213 -0.9575 3221282 PK04_130116 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F21 compound treatment 748760.0 212000.0 0.56 435200.0 -31900.0 -0.09 0.3376 0.5906 3176499 PK04_130117 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F22 compound treatment 533120.0 -4120.0 -0.01 263110.0 -204000.0 -0.56 -0.4037 -0.7208 3221283 PK04_130118 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F23 compound treatment 509030.0 -28200.0 -0.08 451840.0 -15200.0 -0.04 -0.0828 -0.9614 3175968 PK04_130119 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 F24 compound treatment 742970.0 206000.0 0.55 265160.0 -202000.0 -0.55 -0.0034 -0.0043 3221284 PK04_130120 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G01 compound treatment 516730.0 -20500.0 -0.05 218560.0 -249000.0 -0.68 -0.5212 -0.7614 2019328 PK04_130121 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCOCCOCCOCCOCC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G02 compound treatment 360170.0 -177000.0 -0.47 219430.0 -248000.0 -0.68 -0.8152 -0.9843 3211907 PK04_130122 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G03 mock treatment 418760.0 -118000.0 -0.32 725890.0 259000.0 0.71 0.2787 0.3583 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G04 mock treatment 846960.0 310000.0 0.83 274730.0 -192000.0 -0.53 0.2116 0.2156 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G05 compound treatment 811710.0 274000.0 0.73 430670.0 -36400.0 -0.1 0.4477 0.6051 3221285 PK04_130123 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCCCCCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G06 compound treatment 232930.0 -304000.0 -0.81 697600.0 231000.0 0.63 -0.1272 -0.1235 3211815 PK04_130124 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G07 compound treatment 459360.0 -77900.0 -0.21 265180.0 -202000.0 -0.55 -0.539 -0.9105 3221287 PK04_130125 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccccc3F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G08 compound treatment 536550.0 -685.0 0.0 603150.0 136000.0 0.37 0.2629 0.7036 3211803 PK04_130126 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G09 compound treatment 427390.0 -110000.0 -0.29 349650.0 -117000.0 -0.32 -0.4354 -0.9989 3221289 PK04_130127 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCCCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G10 compound treatment 328160.0 -209000.0 -0.56 433180.0 -33900.0 -0.09 -0.4607 -0.8137 3211807 PK04_130128 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G11 compound treatment 347840.0 -189000.0 -0.51 387770.0 -79300.0 -0.22 -0.5116 -0.929 2019311 PK04_130129 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2ccc(cc2)C(=O)OC)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G12 compound treatment 255460.0 -282000.0 -0.75 315040.0 -152000.0 -0.42 -0.8273 -0.9613 3211818 PK04_130130 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G13 compound treatment 496710.0 -40500.0 -0.11 229510.0 -238000.0 -0.65 -0.5377 -0.8133 3221292 PK04_130131 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G14 compound treatment 252970.0 -284000.0 -0.76 685850.0 219000.0 0.6 -0.1122 -0.1158 3080207 PK04_130132 OCCC[C@H](O)c1ccc(O)c(F)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G15 compound treatment 320960.0 -216000.0 -0.58 490050.0 23000.0 0.06 -0.3639 -0.6261 2019470 PK04_130133 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2coc3ccccc3c2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G16 compound treatment 670830.0 134000.0 0.36 458690.0 -8380.0 -0.02 0.2361 0.6602 3080225 PK04_130134 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G17 compound treatment 191760.0 -345000.0 -0.92 208880.0 -258000.0 -0.71 -1.1537 -0.9915 3221294 PK04_130135 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4coc5ccccc5c4=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G18 compound treatment 193530.0 -344000.0 -0.92 349670.0 -117000.0 -0.32 -0.877 -0.9014 3211806 PK04_130136 CO[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G19 mock treatment 661530.0 124000.0 0.33 211260.0 -256000.0 -0.7 -0.2618 -0.3371 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G20 mock treatment 803250.0 266000.0 0.71 535640.0 68600.0 0.19 0.6355 0.8646 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G21 compound treatment 766960.0 230000.0 0.61 310820.0 -156000.0 -0.43 0.1306 0.1744 2019463 PK04_130137 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3coc4ccccc4c3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G22 compound treatment 659700.0 122000.0 0.33 214250.0 -253000.0 -0.69 -0.2595 -0.3382 3080280 PK04_130138 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G23 compound treatment 703070.0 166000.0 0.44 308970.0 -158000.0 -0.43 0.0063 0.0102 3221297 PK04_130139 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 G24 compound treatment 538110.0 875.0 0.0 284000.0 -183000.0 -0.5 -0.3537 -0.7038 3211912 PK04_130140 C[C@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H01 compound treatment 801050.0 264000.0 0.7 474720.0 7650.0 0.02 0.5131 0.7279 3052931 PK04_130141 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H02 compound treatment 812400.0 275000.0 0.73 312210.0 -155000.0 -0.43 0.2191 0.258 3221300 PK04_130142 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H03 mock treatment 528540.0 -8700.0 -0.02 757690.0 291000.0 0.8 0.5478 0.6862 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H04 mock treatment 773540.0 236000.0 0.63 754560.0 287000.0 0.79 1.0044 0.9939 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H05 compound treatment 316740.0 -220000.0 -0.59 448900.0 -18200.0 -0.05 -0.4517 -0.7642 3176330 PK04_130143 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H06 compound treatment 450910.0 -86300.0 -0.23 562180.0 95100.0 0.26 0.0216 0.062 3221301 PK04_130144 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H07 compound treatment 492800.0 -44400.0 -0.12 592840.0 126000.0 0.35 0.1602 0.4389 3176685 PK04_130145 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H08 compound treatment 739720.0 202000.0 0.54 332990.0 -134000.0 -0.37 0.1221 0.1867 3221302 PK04_130146 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H09 compound treatment 799400.0 262000.0 0.7 494150.0 27100.0 0.07 0.5477 0.7778 3052879 PK04_130147 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H10 compound treatment 328800.0 -208000.0 -0.56 294310.0 -173000.0 -0.47 -0.729 -0.9968 3221303 PK04_130148 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H11 compound treatment 711450.0 174000.0 0.47 741280.0 274000.0 0.75 0.8614 0.9733 3176775 PK04_130149 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H12 compound treatment 197560.0 -340000.0 -0.91 222280.0 -245000.0 -0.67 -1.1167 -0.9891 3221305 PK04_130150 COc1cc2c3N(C(=O)[C@]42O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)O)C(C)(C)C=C(C)c3c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H13 compound treatment 570250.0 33000.0 0.09 637140.0 170000.0 0.47 0.3925 0.826 3052783 PK04_130151 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H14 compound treatment 230790.0 -306000.0 -0.82 474470.0 7400.0 0.02 -0.5644 -0.6893 3221307 PK04_130152 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H15 compound treatment 803490.0 266000.0 0.71 275170.0 -192000.0 -0.53 0.1303 0.1473 3176626 PK04_130153 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H16 compound treatment 273220.0 -264000.0 -0.71 235380.0 -232000.0 -0.64 -0.9484 -0.9987 3221308 PK04_130154 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H17 compound treatment 516570.0 -20700.0 -0.06 259100.0 -208000.0 -0.57 -0.4428 -0.7719 3176501 PK04_130155 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H18 compound treatment 257790.0 -279000.0 -0.75 623380.0 156000.0 0.43 -0.2243 -0.2605 3221309 PK04_130156 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H19 mock treatment 666640.0 129000.0 0.35 312030.0 -155000.0 -0.43 -0.0566 -0.1032 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H20 mock treatment 713830.0 177000.0 0.47 270720.0 -196000.0 -0.54 -0.0476 -0.0665 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H21 compound treatment 332110.0 -205000.0 -0.55 257600.0 -209000.0 -0.58 -0.7941 -0.9997 3052741 PK04_130157 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H22 compound treatment 509200.0 -28000.0 -0.07 448330.0 -18700.0 -0.05 -0.0893 -0.9832 3221310 PK04_130158 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H23 compound treatment 343360.0 -194000.0 -0.52 413490.0 -53600.0 -0.15 -0.4702 -0.8734 3176203 PK04_130159 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 H24 compound treatment 326770.0 -210000.0 -0.56 305610.0 -161000.0 -0.44 -0.7109 -0.9931 3221312 PK04_130160 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I01 compound treatment 786500.0 249000.0 0.67 582040.0 115000.0 0.32 0.694 0.9419 3221313 PK04_130161 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I02 compound treatment 599520.0 62300.0 0.17 499680.0 32600.0 0.09 0.181 0.9578 3080209 PK04_130162 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I03 compound treatment 264640.0 -273000.0 -0.73 415730.0 -51300.0 -0.14 -0.6145 -0.8286 3221314 PK04_130163 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I04 compound treatment 465950.0 -71300.0 -0.19 497810.0 30700.0 0.08 -0.0749 -0.3599 3069956 PK04_130164 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I05 mock treatment 338080.0 -199000.0 -0.53 811130.0 344000.0 0.94 0.2918 0.2692 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I06 mock treatment 403740.0 -133000.0 -0.36 782020.0 315000.0 0.86 0.3593 0.3841 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I07 compound treatment 520280.0 -17000.0 -0.05 601130.0 134000.0 0.37 0.2282 0.6155 3221316 PK04_130165 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I08 compound treatment 586290.0 49100.0 0.13 697150.0 230000.0 0.63 0.5393 0.836 3211693 PK04_130166 CO[C@H](CCO)[C@H](O)c1ccc(O)c(F)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I09 compound treatment 388860.0 -148000.0 -0.4 512370.0 45300.0 0.12 -0.1923 -0.4629 2019335 PK04_130167 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I10 compound treatment 233460.0 -304000.0 -0.81 342150.0 -125000.0 -0.34 -0.8162 -0.9266 3080278 PK04_130168 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I11 compound treatment 375230.0 -162000.0 -0.43 794480.0 327000.0 0.9 0.3296 0.3304 3221318 PK04_130169 COc1cc2c[n+](Cc3cc4OCOc4cc3Br)ccc2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I12 compound treatment 302270.0 -235000.0 -0.63 365150.0 -102000.0 -0.28 -0.6416 -0.9338 3211911 PK04_130170 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I13 compound treatment 688750.0 152000.0 0.4 280330.0 -187000.0 -0.51 -0.0763 -0.1169 3221319 PK04_130171 COc1cc2c[n+](Cc3sc4ccccc4c3Cl)ccc2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I14 compound treatment 690970.0 154000.0 0.41 293610.0 -173000.0 -0.48 -0.0464 -0.0738 3080208 PK04_130172 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I15 compound treatment 180090.0 -357000.0 -0.95 263630.0 -203000.0 -0.56 -1.0695 -0.9675 3221320 PK04_130173 COc1cc2c[n+](Cc3ccc(o3)[N+](=O)[O-])ccc2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I16 compound treatment 254140.0 -283000.0 -0.76 458810.0 -8260.0 -0.02 -0.5507 -0.728 3080223 PK04_130174 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I17 compound treatment 445240.0 -92000.0 -0.25 792220.0 325000.0 0.89 0.4575 0.4941 3221321 PK04_130175 COc1cc2c[n+](Cc3cccc(OC(F)(F)F)c3)ccc2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I18 compound treatment 249200.0 -288000.0 -0.77 187450.0 -280000.0 -0.77 -1.0868 -1.0 3080282 PK04_130176 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I19 compound treatment 766590.0 229000.0 0.61 243890.0 -223000.0 -0.61 -1.0E-4 -1.0E-4 3221322 PK04_130177 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)CCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I20 compound treatment 581690.0 44500.0 0.12 731640.0 265000.0 0.73 0.5976 0.8119 3211594 PK04_130178 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I21 mock treatment 646980.0 110000.0 0.29 517520.0 50500.0 0.14 0.3052 0.9414 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I22 mock treatment 229120.0 -308000.0 -0.82 251420.0 -216000.0 -0.59 -1.0006 -0.9869 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I23 compound treatment 605560.0 68300.0 0.18 254370.0 -213000.0 -0.58 -0.2839 -0.464 3221324 PK04_130179 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4cccs4)CCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 I24 compound treatment 203930.0 -333000.0 -0.89 613180.0 146000.0 0.4 -0.3459 -0.3542 3211811 PK04_130180 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J01 compound treatment 805410.0 268000.0 0.72 698470.0 231000.0 0.64 0.9557 0.9982 3176788 PK04_130181 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J02 compound treatment 221730.0 -316000.0 -0.84 473150.0 6080.0 0.02 -0.5841 -0.693 3221326 PK04_130182 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J03 compound treatment 756680.0 219000.0 0.59 401760.0 -65300.0 -0.18 0.2877 0.4693 3176789 PK04_130183 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J04 compound treatment 294620.0 -243000.0 -0.65 551250.0 84200.0 0.23 -0.2948 -0.4285 3221328 PK04_130184 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J05 mock treatment 783590.0 246000.0 0.66 438490.0 -28600.0 -0.08 0.4098 0.6184 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J06 mock treatment 390020.0 -147000.0 -0.39 442720.0 -24300.0 -0.07 -0.3253 -0.8156 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J07 compound treatment 300120.0 -237000.0 -0.63 527080.0 60000.0 0.16 -0.3313 -0.5063 3052827 PK04_130185 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J08 compound treatment 267320.0 -270000.0 -0.72 174090.0 -293000.0 -0.8 -1.0785 -0.9985 3221330 PK04_130186 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J09 compound treatment 290190.0 -247000.0 -0.66 442290.0 -24800.0 -0.07 -0.5147 -0.7759 3052794 PK04_130187 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J10 compound treatment 684690.0 147000.0 0.39 682950.0 216000.0 0.59 0.6976 0.9803 3221332 PK04_130188 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J11 compound treatment 300250.0 -237000.0 -0.63 767770.0 301000.0 0.83 0.1362 0.1309 3176437 PK04_130189 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J12 compound treatment 309220.0 -228000.0 -0.61 365140.0 -102000.0 -0.28 -0.6285 -0.9378 3221334 PK04_130190 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J13 compound treatment 329040.0 -208000.0 -0.56 212690.0 -254000.0 -0.7 -0.887 -0.9936 3176038 PK04_130191 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J14 compound treatment 219870.0 -317000.0 -0.85 149330.0 -318000.0 -0.87 -1.2162 -0.9999 3221335 PK04_130192 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCC4=O)c5ccccc52)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J15 compound treatment 518040.0 -19200.0 -0.05 249550.0 -218000.0 -0.6 -0.4585 -0.765 3052796 PK04_130193 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J16 compound treatment 215360.0 -322000.0 -0.86 195760.0 -271000.0 -0.74 -1.1346 -0.9974 3221337 PK04_130194 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J17 compound treatment 511140.0 -26100.0 -0.07 270590.0 -196000.0 -0.54 -0.4307 -0.7919 3176331 PK04_130195 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J18 compound treatment 433220.0 -104000.0 -0.28 261290.0 -206000.0 -0.56 -0.5959 -0.9466 3221339 PK04_130196 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J19 compound treatment 325400.0 -212000.0 -0.57 274930.0 -192000.0 -0.53 -0.7731 -0.9994 3176671 PK04_130197 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J20 compound treatment 524320.0 -12900.0 -0.03 282500.0 -185000.0 -0.51 -0.3827 -0.7535 3221341 PK04_130198 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5ccccc5Oc6ccccc46)c7ccccc72)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J21 mock treatment 356410.0 -181000.0 -0.48 347880.0 -119000.0 -0.33 -0.5729 -0.982 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J22 mock treatment 276130.0 -261000.0 -0.7 259160.0 -208000.0 -0.57 -0.8967 -0.9951 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J23 compound treatment 252700.0 -285000.0 -0.76 290900.0 -176000.0 -0.48 -0.8794 -0.9762 3176271 PK04_130199 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 J24 compound treatment 261860.0 -275000.0 -0.74 207580.0 -259000.0 -0.71 -1.0238 -0.9999 3221343 PK04_130200 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5ccccc5Oc6ccccc46)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K01 compound treatment 252190.0 -285000.0 -0.76 225320.0 -242000.0 -0.66 -1.0077 -0.9977 3221345 PK04_130201 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)c4ccc(CO)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K02 compound treatment 674450.0 137000.0 0.37 201280.0 -266000.0 -0.73 -0.2568 -0.3145 3211905 PK04_130202 C[C@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K03 compound treatment 247200.0 -290000.0 -0.77 361410.0 -106000.0 -0.29 -0.7529 -0.9102 3221347 PK04_130203 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#Cc4ccccc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K04 compound treatment 838480.0 301000.0 0.8 677970.0 211000.0 0.58 0.9784 0.987 3211691 PK04_130204 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K05 compound treatment 335680.0 -202000.0 -0.54 605330.0 138000.0 0.38 -0.1123 -0.1704 3221348 PK04_130205 COc1cc2CCN(C)C(C#Cc3ccccc3)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K06 compound treatment 864960.0 328000.0 0.88 497760.0 30700.0 0.08 0.6786 0.7716 3211813 PK04_130206 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K07 mock treatment 800880.0 264000.0 0.7 584010.0 117000.0 0.32 0.725 0.9367 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K08 mock treatment 472220.0 -65000.0 -0.17 500160.0 33100.0 0.09 -0.0585 -0.2987 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K09 compound treatment 450480.0 -86800.0 -0.23 332000.0 -135000.0 -0.37 -0.4261 -0.9744 3221349 PK04_130207 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#Cc4ccccc4)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K10 compound treatment 65880.0 -471000.0 -1.26 105180.0 -362000.0 -0.99 -1.5928 -0.9931 3211817 PK04_130208 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K11 compound treatment 257340.0 -280000.0 -0.75 257090.0 -210000.0 -0.58 -0.9363 -0.9918 3221350 PK04_130209 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(O)cc13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K12 compound treatment 227740.0 -309000.0 -0.83 298620.0 -168000.0 -0.46 -0.9115 -0.9623 3080279 PK04_130210 C[C@@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K13 compound treatment 764400.0 227000.0 0.61 527040.0 60000.0 0.16 0.5455 0.8676 3221351 PK04_130211 COCC#CC1N(C)CCc2cc(OC)c(O)cc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K14 compound treatment 291300.0 -246000.0 -0.66 490350.0 23300.0 0.06 -0.4193 -0.6353 3080188 PK04_130212 CO[C@H](CCO)[C@H](O)c1ccc(OC)c(O)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K15 mock treatment 254350.0 -283000.0 -0.76 528840.0 61800.0 0.17 -0.4144 -0.5351 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K16 mock treatment 285660.0 -252000.0 -0.67 825040.0 358000.0 0.98 0.2198 0.1846 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K17 compound treatment 553870.0 16600.0 0.04 628800.0 162000.0 0.44 0.3454 0.774 3221353 PK04_130213 COCC#CC1N(Cc2ccc(o2)[N+](=O)[O-])CCc3cc(OC)c(O)cc13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K18 compound treatment 427910.0 -109000.0 -0.29 231680.0 -235000.0 -0.65 -0.6634 -0.9355 3080221 PK04_130214 CO[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K19 compound treatment 277400.0 -260000.0 -0.69 211160.0 -256000.0 -0.7 -0.9875 -1.0 3221354 PK04_130215 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K20 compound treatment 844800.0 308000.0 0.82 515700.0 48600.0 0.13 0.6753 0.8114 3211696 PK04_130216 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K21 compound treatment 210820.0 -326000.0 -0.87 344430.0 -123000.0 -0.34 -0.8546 -0.9144 3221356 PK04_130217 COc1cc2CCN(C)C(C#C)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K22 compound treatment 775470.0 238000.0 0.64 794780.0 328000.0 0.9 1.0861 0.9856 3211816 PK04_130218 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K23 mock treatment 442890.0 -94300.0 -0.25 271910.0 -195000.0 -0.54 -0.557 -0.9408 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 K24 mock treatment 859120.0 322000.0 0.86 240600.0 -226000.0 -0.62 0.1683 0.1586 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L01 compound treatment 738030.0 201000.0 0.54 612710.0 146000.0 0.4 0.662 0.9895 3176382 PK04_130219 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L02 compound treatment 504720.0 -32500.0 -0.09 810880.0 344000.0 0.94 0.606 0.6393 3221357 PK04_130220 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCCCC4=O)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L03 compound treatment 276230.0 -261000.0 -0.7 755910.0 289000.0 0.79 0.0678 0.0642 3176383 PK04_130221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L04 compound treatment 415600.0 -122000.0 -0.32 507440.0 40400.0 0.11 -0.1513 -0.4409 3221359 PK04_130222 C[C@H](O)C(=O)Nc1ccc2N(CC=C)C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L05 compound treatment 755210.0 218000.0 0.58 519430.0 52400.0 0.14 0.5133 0.856 3052642 PK04_130223 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L06 compound treatment 216000.0 -321000.0 -0.86 317280.0 -150000.0 -0.41 -0.8975 -0.9433 3221361 PK04_130224 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L07 mock treatment 664190.0 127000.0 0.34 779590.0 313000.0 0.86 0.8465 0.9175 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L08 mock treatment 408320.0 -129000.0 -0.34 727880.0 261000.0 0.72 0.2628 0.3308 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L09 compound treatment 429790.0 -107000.0 -0.29 387520.0 -79500.0 -0.22 -0.3574 -0.9909 3176673 PK04_130225 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L10 compound treatment 397340.0 -140000.0 -0.37 304320.0 -163000.0 -0.45 -0.5802 -0.996 3221363 PK04_130226 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L11 compound treatment 516400.0 -20800.0 -0.06 648320.0 181000.0 0.5 0.3125 0.6241 3052529 PK04_130227 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L12 compound treatment 291100.0 -246000.0 -0.66 332750.0 -134000.0 -0.37 -0.7256 -0.9626 3221365 PK04_130228 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L13 compound treatment 408010.0 -129000.0 -0.35 575710.0 109000.0 0.3 -0.0332 -0.0727 3052693 PK04_130229 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L14 compound treatment 619240.0 82000.0 0.22 200700.0 -266000.0 -0.73 -0.3622 -0.4745 3221366 PK04_130230 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L15 mock treatment 314580.0 -223000.0 -0.59 436480.0 -30600.0 -0.08 -0.4799 -0.799 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L16 mock treatment 678290.0 141000.0 0.38 663860.0 197000.0 0.54 0.6484 0.9845 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L17 compound treatment 377120.0 -160000.0 -0.43 276490.0 -191000.0 -0.52 -0.6724 -0.995 3176205 PK04_130231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L18 compound treatment 347840.0 -189000.0 -0.51 320130.0 -147000.0 -0.4 -0.643 -0.9937 3221368 PK04_130232 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCOC4=O)c5ccccc52)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L19 compound treatment 866890.0 330000.0 0.88 312510.0 -155000.0 -0.42 0.3226 0.33 3176125 PK04_130233 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L20 compound treatment 320160.0 -217000.0 -0.58 293850.0 -173000.0 -0.48 -0.7462 -0.9952 3221370 PK04_130234 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)F)c3c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L21 compound treatment 513510.0 -23700.0 -0.06 289120.0 -178000.0 -0.49 -0.3903 -0.7922 3052877 PK04_130235 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L22 compound treatment 548520.0 11300.0 0.03 201920.0 -265000.0 -0.73 -0.4934 -0.6772 3221372 PK04_130236 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(NC(=O)C)cc32)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L23 mock treatment 491260.0 -46000.0 -0.12 543710.0 76600.0 0.21 0.062 0.2543 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 L24 mock treatment 855360.0 318000.0 0.85 252640.0 -214000.0 -0.59 0.1846 0.1785 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M01 compound treatment 324560.0 -213000.0 -0.57 426970.0 -40100.0 -0.11 -0.4795 -0.8287 3221374 PK04_130237 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#C)c2cc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M02 compound treatment 767490.0 230000.0 0.62 759430.0 292000.0 0.8 1.0024 0.9914 3211810 PK04_130238 C[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M03 compound treatment 643580.0 106000.0 0.28 367650.0 -99400.0 -0.27 0.0079 0.0199 3221375 PK04_130239 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M04 compound treatment 798590.0 261000.0 0.7 689090.0 222000.0 0.61 0.9246 0.9977 3080224 PK04_130240 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M05 compound treatment 762820.0 226000.0 0.6 663420.0 196000.0 0.54 0.8072 0.9985 3221376 PK04_130241 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M06 compound treatment 642730.0 105000.0 0.28 287620.0 -179000.0 -0.49 -0.1491 -0.2627 3211820 PK04_130242 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M07 compound treatment 588510.0 51300.0 0.14 312430.0 -155000.0 -0.42 -0.2034 -0.4559 3221377 PK04_130243 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M08 compound treatment 675940.0 139000.0 0.37 661020.0 194000.0 0.53 0.6385 0.9843 3211694 PK04_130244 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M09 mock treatment 740180.0 203000.0 0.54 778400.0 311000.0 0.85 0.9877 0.9758 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M10 mock treatment 625070.0 87800.0 0.23 804100.0 337000.0 0.93 0.8202 0.8592 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M11 compound treatment 406880.0 -130000.0 -0.35 349170.0 -118000.0 -0.32 -0.4751 -0.9993 3221378 PK04_130245 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M12 compound treatment 800180.0 263000.0 0.7 499360.0 32300.0 0.09 0.5593 0.7901 3080189 PK04_130246 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M13 mock treatment 806670.0 269000.0 0.72 307170.0 -160000.0 -0.44 0.1985 0.2354 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M14 mock treatment 365440.0 -172000.0 -0.46 419840.0 -47200.0 -0.13 -0.4161 -0.8727 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M15 compound treatment 300800.0 -236000.0 -0.63 606250.0 139000.0 0.38 -0.1763 -0.2389 3221379 PK04_130247 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M16 compound treatment 709760.0 173000.0 0.46 651010.0 184000.0 0.51 0.6829 0.999 3211679 PK04_130248 CO[C@@H](CCO)[C@@H](O)c1ccc(OC)c(O)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M17 compound treatment 301730.0 -236000.0 -0.63 752880.0 286000.0 0.78 0.1101 0.1094 3221380 PK04_130249 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M18 compound treatment 413790.0 -123000.0 -0.33 584640.0 118000.0 0.32 -0.0049 -0.0106 3211808 PK04_130250 C[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M19 mock treatment 716740.0 180000.0 0.48 476960.0 9890.0 0.03 0.3582 0.746 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M20 compound treatment 628160.0 90900.0 0.24 594900.0 128000.0 0.35 0.4199 0.9838 3080271 PK04_130251 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M21 mock treatment 700710.0 163000.0 0.44 750680.0 284000.0 0.78 0.8593 0.9626 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M22 compound treatment 451600.0 -85600.0 -0.23 257620.0 -209000.0 -0.58 -0.5683 -0.9184 3211910 PK04_130252 C[C@@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M23 mock treatment 520400.0 -16800.0 -0.04 363080.0 -104000.0 -0.29 -0.2337 -0.8085 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 M24 compound treatment 462470.0 -74800.0 -0.2 335950.0 -131000.0 -0.36 -0.3957 -0.9614 3211692 PK04_130253 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N01 compound treatment 760710.0 223000.0 0.6 739200.0 272000.0 0.75 0.9504 0.9938 3176433 PK04_130254 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N02 compound treatment 231040.0 -306000.0 -0.82 286460.0 -181000.0 -0.5 -0.9289 -0.9712 3221382 PK04_130255 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N03 compound treatment 645620.0 108000.0 0.29 742600.0 276000.0 0.76 0.7396 0.9131 3175967 PK04_130256 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N04 compound treatment 683160.0 146000.0 0.39 770640.0 304000.0 0.83 0.8649 0.9401 3221383 PK04_130257 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N05 compound treatment 729130.0 192000.0 0.51 585120.0 118000.0 0.32 0.5916 0.9756 3052653 PK04_130258 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N06 compound treatment 689940.0 153000.0 0.41 328510.0 -139000.0 -0.38 0.0194 0.0348 3221385 PK04_130259 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N07 compound treatment 713360.0 176000.0 0.47 182150.0 -285000.0 -0.78 -0.2205 -0.2415 3052758 PK04_130260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N08 compound treatment 443850.0 -93400.0 -0.25 491800.0 24700.0 0.07 -0.1284 -0.4965 3221386 PK04_130261 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N09 mock treatment 726730.0 189000.0 0.51 725480.0 258000.0 0.71 0.8596 0.9863 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N10 mock treatment 572480.0 35200.0 0.09 755970.0 289000.0 0.79 0.6274 0.7855 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N11 compound treatment 450690.0 -86500.0 -0.23 705620.0 239000.0 0.65 0.2997 0.4314 3176332 PK04_130262 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N12 compound treatment 497280.0 -40000.0 -0.11 265870.0 -201000.0 -0.55 -0.466 -0.8284 3221388 PK04_130263 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N13 mock treatment 522580.0 -14700.0 -0.04 621380.0 154000.0 0.42 0.2719 0.6391 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N14 mock treatment 459420.0 -77800.0 -0.21 740520.0 273000.0 0.75 0.3839 0.4928 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N15 compound treatment 494160.0 -43100.0 -0.12 630930.0 164000.0 0.45 0.2368 0.5099 3176440 PK04_130264 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N16 compound treatment 514440.0 -22800.0 -0.06 433010.0 -34100.0 -0.09 -0.1092 -0.9784 3221389 PK04_130265 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5cccc6cccc4c56)c7ccccc72)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N17 compound treatment 274140.0 -263000.0 -0.7 300220.0 -167000.0 -0.46 -0.8208 -0.9785 3174818 PK04_130266 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N18 compound treatment 405980.0 -131000.0 -0.35 300900.0 -166000.0 -0.46 -0.5705 -0.9915 3221391 PK04_130267 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N19 compound treatment 650330.0 113000.0 0.3 502840.0 35800.0 0.1 0.283 0.8911 3052539 PK04_130268 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N20 compound treatment 301000.0 -236000.0 -0.63 184070.0 -283000.0 -0.78 -0.9956 -0.9947 3221392 PK04_130269 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N(C=O)c5ccccc5)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N21 compound treatment 367170.0 -170000.0 -0.45 697860.0 231000.0 0.63 0.1268 0.1627 3052582 PK04_130270 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N22 compound treatment 322120.0 -215000.0 -0.57 521250.0 54200.0 0.15 -0.3011 -0.5073 3221394 PK04_130271 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@@]3(O[C@@H](CCO)[C@@H]([C@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N23 compound treatment 776360.0 239000.0 0.64 504450.0 37400.0 0.1 0.5242 0.8103 3052791 PK04_130272 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 N24 compound treatment 276980.0 -260000.0 -0.7 417530.0 -49500.0 -0.14 -0.5877 -0.8297 3221396 PK04_130273 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O01 mock treatment 582150.0 44900.0 0.12 582740.0 116000.0 0.32 0.3094 0.9114 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O02 compound treatment 394400.0 -143000.0 -0.38 625330.0 158000.0 0.43 0.0375 0.0648 3211913 PK04_130274 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O03 mock treatment 386410.0 -151000.0 -0.4 517440.0 50400.0 0.14 -0.1871 -0.4392 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O04 mock treatment 496420.0 -40800.0 -0.11 662580.0 196000.0 0.54 0.3025 0.5522 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O05 mock treatment 511920.0 -25300.0 -0.07 447630.0 -19400.0 -0.05 -0.0855 -0.9931 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O06 mock treatment 310050.0 -227000.0 -0.61 414440.0 -52600.0 -0.14 -0.5312 -0.8517 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O07 mock treatment 673650.0 136000.0 0.36 445980.0 -21100.0 -0.06 0.2167 0.5874 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O08 mock treatment 451850.0 -85400.0 -0.23 296090.0 -171000.0 -0.47 -0.4932 -0.945 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O09 mock treatment 527780.0 -9460.0 -0.03 286880.0 -180000.0 -0.49 -0.3677 -0.7422 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O10 mock treatment 600220.0 63000.0 0.17 352760.0 -114000.0 -0.31 -0.1029 -0.2891 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O11 mock treatment 644770.0 108000.0 0.29 374020.0 -93000.0 -0.26 0.0225 0.0585 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O12 mock treatment 707790.0 171000.0 0.46 239360.0 -228000.0 -0.63 -0.1199 -0.155 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O13 mock treatment 418090.0 -119000.0 -0.32 312800.0 -154000.0 -0.42 -0.5245 -0.9901 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O14 mock treatment 608320.0 71100.0 0.19 223910.0 -243000.0 -0.67 -0.3378 -0.4867 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O15 mock treatment 332930.0 -204000.0 -0.55 366980.0 -100000.0 -0.27 -0.5802 -0.9496 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O16 mock treatment 658910.0 122000.0 0.32 280550.0 -187000.0 -0.51 -0.1323 -0.2181 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O17 mock treatment 329790.0 -207000.0 -0.55 437540.0 -29500.0 -0.08 -0.4491 -0.802 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O18 mock treatment 429360.0 -108000.0 -0.29 373610.0 -93500.0 -0.26 -0.3852 -0.9983 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O19 mock treatment 515260.0 -22000.0 -0.06 275600.0 -191000.0 -0.53 -0.4132 -0.7812 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O20 mock treatment 537940.0 705.0 0.0 208040.0 -259000.0 -0.71 -0.5015 -0.7052 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O21 mock treatment 442720.0 -94500.0 -0.25 289200.0 -178000.0 -0.49 -0.5238 -0.9529 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O22 mock treatment 210720.0 -327000.0 -0.87 228280.0 -239000.0 -0.66 -1.0802 -0.9901 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O23 mock treatment 637570.0 100000.0 0.27 366650.0 -100000.0 -0.28 -0.0054 -0.0141 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 O24 mock treatment 503810.0 -33400.0 -0.09 500850.0 33800.0 0.09 0.0025 0.0191 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P01 compound treatment 498080.0 -39200.0 -0.1 509670.0 42600.0 0.12 0.0088 0.0558 3175838 PK04_130275 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P02 compound treatment 302000.0 -235000.0 -0.63 446610.0 -20500.0 -0.06 -0.484 -0.7672 3221398 PK04_130276 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P03 compound treatment 379250.0 -158000.0 -0.42 352510.0 -115000.0 -0.31 -0.5208 -0.9895 3052740 PK04_130277 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P04 compound treatment 246120.0 -291000.0 -0.78 207200.0 -260000.0 -0.71 -1.0543 -0.9991 3221399 PK04_130278 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P05 compound treatment 253290.0 -284000.0 -0.76 461680.0 -5390.0 -0.01 -0.5467 -0.7208 3176784 PK04_130279 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P06 compound treatment 260970.0 -276000.0 -0.74 373780.0 -93300.0 -0.26 -0.7029 -0.8999 3221400 PK04_130280 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P07 compound treatment 462110.0 -75100.0 -0.2 363230.0 -104000.0 -0.29 -0.3435 -0.9852 3052752 PK04_130281 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P08 compound treatment 301460.0 -236000.0 -0.63 375490.0 -91600.0 -0.25 -0.6231 -0.9189 3221401 PK04_130282 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P09 compound treatment 373560.0 -164000.0 -0.44 255880.0 -211000.0 -0.58 -0.7191 -0.9903 3052788 PK04_130283 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P10 compound treatment 326240.0 -211000.0 -0.56 375170.0 -91900.0 -0.25 -0.5769 -0.9343 3221402 PK04_130284 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P11 mock treatment 270100.0 -267000.0 -0.71 342830.0 -124000.0 -0.34 -0.7457 -0.9429 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P12 mock treatment 180880.0 -356000.0 -0.95 310090.0 -157000.0 -0.43 -0.9778 -0.9358 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P13 compound treatment 282950.0 -254000.0 -0.68 294150.0 -173000.0 -0.47 -0.8159 -0.9847 3052846 PK04_130285 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P14 compound treatment 222440.0 -315000.0 -0.84 235170.0 -232000.0 -0.64 -1.0447 -0.9906 3221404 PK04_130286 C[C@H](O)C(=O)Nc1cccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P15 compound treatment 271270.0 -266000.0 -0.71 268030.0 -199000.0 -0.55 -0.8887 -0.9916 3052836 PK04_130287 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P16 compound treatment 303370.0 -234000.0 -0.62 339630.0 -127000.0 -0.35 -0.6891 -0.9625 3221406 PK04_130288 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P17 compound treatment 192250.0 -345000.0 -0.92 200200.0 -267000.0 -0.73 -1.1696 -0.9935 3176730 PK04_130289 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P18 compound treatment 230200.0 -307000.0 -0.82 244580.0 -222000.0 -0.61 -1.0118 -0.9895 3221407 PK04_130290 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P19 compound treatment 203040.0 -334000.0 -0.89 326370.0 -141000.0 -0.39 -0.9043 -0.9298 3052799 PK04_130291 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P20 compound treatment 175760.0 -361000.0 -0.97 215540.0 -252000.0 -0.69 -1.171 -0.9865 3221408 PK04_130292 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P21 compound treatment 292970.0 -244000.0 -0.65 290180.0 -177000.0 -0.49 -0.8047 -0.9894 3176730 PK04_130293 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P22 compound treatment 174150.0 -363000.0 -0.97 260890.0 -206000.0 -0.57 -1.086 -0.9671 3221410 PK04_130294 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P23 compound treatment 230590.0 -307000.0 -0.82 337040.0 -130000.0 -0.36 -0.8316 -0.9307 3176786 PK04_130295 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2130 P24 compound treatment 236990.0 -300000.0 -0.8 288730.0 -178000.0 -0.49 -0.9133 -0.972 3221411 PK04_130296 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)COc5ccccc45)c6ccccc62)[Si](C)(C)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A01 compound treatment 321810.0 -196000.0 -0.52 160710.0 -232000.0 -0.64 -0.8209 -0.9952 3561840 PK04_181001 CC(C)(C)N(CC=C)C(=O)C1N(Cc2ccccc2)C(=O)C3C(C4OC13C=C4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A02 compound treatment 168190.0 -350000.0 -0.93 384530.0 -8400.0 -0.02 -0.6765 -0.7243 3561841 PK04_181002 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A03 compound treatment 207330.0 -310000.0 -0.83 206370.0 -187000.0 -0.51 -0.9484 -0.9732 3561843 PK04_181003 OC1CCC(CC1)N2C(C(=O)N(CC=C)c3ccccc3)C4(OC5C=C4)C(C5C(=O)OCC=C)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A04 compound treatment 208560.0 -309000.0 -0.83 473660.0 80700.0 0.22 -0.4272 -0.4996 2065615 PK04_181004 COc1ccc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A05 compound treatment 326410.0 -191000.0 -0.51 132280.0 -261000.0 -0.72 -0.8674 -0.9864 3561844 PK04_181005 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccco4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A06 compound treatment 393950.0 -124000.0 -0.33 342560.0 -50400.0 -0.14 -0.3316 -0.9252 3561845 PK04_181006 CCCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)c5ccccc5Cl)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A07 compound treatment 609280.0 91500.0 0.24 391880.0 -1050.0 0.0 0.1708 0.6987 3561847 PK04_181007 Cc1cccc2OC(CC(=O)c12)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A08 compound treatment 326240.0 -192000.0 -0.51 248190.0 -145000.0 -0.4 -0.6427 -0.9922 3561848 PK04_181008 CCCCCN1C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C1=O)c5ccccc5Cl)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A09 compound treatment 217810.0 -300000.0 -0.8 251300.0 -142000.0 -0.39 -0.8414 -0.9449 3561850 PK04_181009 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A10 compound treatment 354560.0 -163000.0 -0.44 193310.0 -200000.0 -0.55 -0.6957 -0.9936 3561851 PK04_181010 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A11 compound treatment 373570.0 -144000.0 -0.39 496710.0 104000.0 0.28 -0.0708 -0.1479 3561853 PK04_181011 Brc1ccc(CN(C(C(=O)NCc2ccccc2)c3ccco3)C(=O)Cc4ccccc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A12 compound treatment 323120.0 -195000.0 -0.52 573920.0 181000.0 0.5 -0.0162 -0.0226 3561854 PK04_181012 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A13 mock treatment 684260.0 167000.0 0.44 604050.0 211000.0 0.58 0.7243 0.9914 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A14 mock treatment 402880.0 -115000.0 -0.31 594470.0 202000.0 0.55 0.1743 0.2755 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A15 compound treatment 229600.0 -288000.0 -0.77 501600.0 109000.0 0.3 -0.3332 -0.4037 3561850 PK04_181013 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A16 compound treatment 373920.0 -144000.0 -0.38 641540.0 249000.0 0.68 0.211 0.2694 3561856 PK04_181014 C[C@H](C(OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@H](CN(CC=C)Cc4ccccc4)N(C(=O)[C@@H]13)C(C)(C)C)c5ccccc5)N(C)C(=O)CCC=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A17 compound treatment 679100.0 161000.0 0.43 209280.0 -184000.0 -0.5 -0.0518 -0.0781 3561858 PK04_181015 COc1ccc(CNC(=O)OCC2c3ccccc3-c4ccccc24)cc1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A18 compound treatment 652760.0 135000.0 0.36 533290.0 140000.0 0.39 0.5275 0.9995 3561856 PK04_181016 C[C@H](C(OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@H](CN(CC=C)Cc4ccccc4)N(C(=O)[C@@H]13)C(C)(C)C)c5ccccc5)N(C)C(=O)CCC=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A19 compound treatment 243520.0 -274000.0 -0.73 461040.0 68100.0 0.19 -0.3857 -0.5102 3561859 PK04_181017 CCOC(=O)C1C2OC3(C=C2)C(N(Cc4cc(OC)cc(OC)c4)C(=O)C13)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A20 compound treatment 638080.0 120000.0 0.32 327170.0 -65800.0 -0.18 0.0996 0.2702 3561860 PK04_181018 COc1ccc(CN2[C@H](C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)[C@@H]([C@H]5C(=O)O)C2=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A21 compound treatment 149350.0 -368000.0 -0.98 202120.0 -191000.0 -0.52 -1.0662 -0.9565 3561861 PK04_181019 CCOC(=O)C1C2OC3(C=C2)C(N(Cc4ccccc4)C(=O)C13)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A22 compound treatment 478050.0 -39700.0 -0.11 318900.0 -74000.0 -0.2 -0.2187 -0.954 3561862 PK04_181020 COc1cc(CN2[C@H](C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)[C@@H]([C@H]5C(=O)O)C2=O)ccc1O[SiH](C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A23 compound treatment 335100.0 -183000.0 -0.49 349860.0 -43100.0 -0.12 -0.4286 -0.8538 3561864 PK04_181021 O=C(Cc1ccccc1)OC(C(=O)NCc2ccccc2)c3ccco3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 A24 compound treatment 449120.0 -68600.0 -0.18 497640.0 105000.0 0.29 0.0737 0.2161 3561865 PK04_181022 COc1cc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)ccc1O[SiH](C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B01 compound treatment 627910.0 110000.0 0.29 391140.0 -1790.0 0.0 0.2046 0.6952 3561867 PK04_181023 OC(CC=C)c1cccc(c1)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B02 compound treatment 724370.0 207000.0 0.55 652480.0 260000.0 0.71 0.8941 0.992 1008566 PK04_181024 Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B03 compound treatment 170240.0 -348000.0 -0.93 282280.0 -111000.0 -0.3 -0.8711 -0.892 3561868 PK04_181025 CC(C)(C)OC(=O)OC(CC=C)c1ccc(cc1)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B04 compound treatment 316660.0 -201000.0 -0.54 453920.0 61000.0 0.17 -0.2614 -0.4646 3561869 PK04_181026 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)[Se]c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B05 compound treatment 356720.0 -161000.0 -0.43 649660.0 257000.0 0.7 0.1943 0.2353 3561870 PK04_181027 OC(CC1CO1)c2ccc(cc2)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B06 compound treatment 323680.0 -194000.0 -0.52 409540.0 16600.0 0.05 -0.3343 -0.6424 3561871 PK04_181028 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B07 compound treatment 632850.0 115000.0 0.31 319680.0 -73200.0 -0.2 0.0752 0.2047 3561872 PK04_181029 OC(CSc1nc(c(o1)c2ccccc2)c3ccccc3)CC(O)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B08 compound treatment 205090.0 -313000.0 -0.84 220700.0 -172000.0 -0.47 -0.9249 -0.9637 3561873 PK04_181030 CC(C)CC1CC(=O)C=C(Cl)N1C(=O)OC(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B09 compound treatment 766740.0 249000.0 0.67 564370.0 171000.0 0.47 0.8031 0.9857 3561874 PK04_181031 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B10 compound treatment 659200.0 141000.0 0.38 297880.0 -95000.0 -0.26 0.0826 0.18 3561875 PK04_181032 COC(=O)C1=C(Cl)N(C(CC(C)C)CC1=O)C(=O)OC(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B11 compound treatment 727270.0 210000.0 0.56 584440.0 192000.0 0.53 0.7675 0.9995 3561876 PK04_181033 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B12 compound treatment 307200.0 -211000.0 -0.56 273060.0 -120000.0 -0.33 -0.6304 -0.9674 3561877 PK04_181034 COC(=O)C1=C(OC)N(C(CC(C)C)CC1=O)C(=O)OC(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B13 mock treatment 646010.0 128000.0 0.34 490000.0 97100.0 0.27 0.4307 0.9923 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B14 mock treatment 476850.0 -40900.0 -0.11 283640.0 -109000.0 -0.3 -0.2894 -0.9063 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B15 compound treatment 329780.0 -188000.0 -0.5 297310.0 -95600.0 -0.26 -0.5406 -0.9543 3561878 PK04_181035 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B16 compound treatment 6480.0 -511000.0 -1.37 8490.0 -384000.0 -1.06 -1.7119 -0.9919 3561879 PK04_181036 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)I 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B17 compound treatment 653930.0 136000.0 0.36 377120.0 -15800.0 -0.04 0.2265 0.6184 3561880 PK04_181037 OC(CC1CO1)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B18 compound treatment 634400.0 117000.0 0.31 723590.0 331000.0 0.91 0.8622 0.8984 3561881 PK04_181038 CC(C)(C)OC(=O)NCC=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B19 compound treatment 594800.0 77100.0 0.21 333810.0 -59100.0 -0.16 0.0308 0.1174 3561882 PK04_181039 CN(CC(O)CC(O)c1ccccc1)Cc2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B20 compound treatment 499160.0 -18600.0 -0.05 215570.0 -177000.0 -0.49 -0.3794 -0.7752 3561883 PK04_181040 COc1ccc(CN(C(=C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B21 compound treatment 716680.0 199000.0 0.53 640860.0 248000.0 0.68 0.857 0.9925 3561884 PK04_181041 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccc(cc6)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B22 compound treatment 8510.0 -509000.0 -1.36 5930.0 -387000.0 -1.06 -1.7131 -0.9925 3561885 PK04_181042 COc1ccc(CNS(=O)(=O)c2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])c(OC)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B23 compound treatment 711390.0 194000.0 0.52 260490.0 -132000.0 -0.36 0.1086 0.1718 3561886 PK04_181043 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccncc3)CC(O2)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 B24 compound treatment 245690.0 -272000.0 -0.73 44040.0 -349000.0 -0.96 -1.1911 -0.9907 3561887 PK04_181044 Brc1ccc(cc1)S(=O)(=O)N2C[C@H]2C=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C01 compound treatment 438750.0 -79000.0 -0.21 541280.0 148000.0 0.41 0.1388 0.3026 3561889 PK04_181045 O=C(Cc1ccccc1)N2CC(=O)Oc3ccccc23 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C02 compound treatment 624680.0 107000.0 0.29 593190.0 200000.0 0.55 0.5907 0.9535 3561890 PK04_181046 CCCCCNC(=O)[C@H]1N(C(=O)[C@@H]2[C@H](C3OC12C=C3)C(=O)OCC)c4ccccc4Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C03 compound treatment 457030.0 -60700.0 -0.16 510300.0 117000.0 0.32 0.1132 0.3137 3561892 PK04_181047 CCOC(=O)C1C2OC3(C=C2)C(N(CCCCCCO)C(=O)C13)C(=O)N(CC=C)Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C04 compound treatment 688160.0 170000.0 0.46 543970.0 151000.0 0.41 0.6151 0.9989 2065568 PK04_181048 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C05 compound treatment 10890.0 -507000.0 -1.35 15520.0 -377000.0 -1.04 -1.6899 -0.9913 3561893 PK04_181049 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)OCC=C)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C06 compound treatment 599800.0 82100.0 0.22 519430.0 127000.0 0.35 0.4006 0.9754 2065566 PK04_181050 CCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C07 compound treatment 371010.0 -147000.0 -0.39 243680.0 -149000.0 -0.41 -0.5669 -0.9998 3561894 PK04_181051 CCOC(=O)C1C2OC3(C=C2)C(N(C4CCC(O)CC4)C(=O)C13)C(=O)N(CC=C)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C08 compound treatment 517530.0 -216.0 0.0 506530.0 114000.0 0.31 0.2201 0.7058 2065605 PK04_181052 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C09 compound treatment 565730.0 48000.0 0.13 448000.0 55100.0 0.15 0.1975 0.9966 3561895 PK04_181053 O=C(Cc1ccccc1)OC(COCc2ccccc2)C(=O)NCc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C10 compound treatment 558300.0 40600.0 0.11 498170.0 105000.0 0.29 0.2809 0.9103 2065603 PK04_181054 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3cccs3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C11 mock treatment 489380.0 -28400.0 -0.08 475650.0 82700.0 0.23 0.107 0.447 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C12 mock treatment 552930.0 35200.0 0.09 225040.0 -168000.0 -0.46 -0.2595 -0.5516 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C13 compound treatment 313310.0 -204000.0 -0.55 235570.0 -157000.0 -0.43 -0.6916 -0.9933 3561896 PK04_181055 CCOC(=O)C1C2OC3(C=C2)C(N(C4CCC(O)CC4)C(=O)C13)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C14 compound treatment 452890.0 -64900.0 -0.17 318880.0 -74000.0 -0.2 -0.2662 -0.9968 2065601 PK04_181056 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C15 mock treatment 485480.0 -32300.0 -0.09 599860.0 207000.0 0.57 0.3408 0.5931 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C16 mock treatment 630370.0 113000.0 0.3 331310.0 -61600.0 -0.17 0.0931 0.2697 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C17 compound treatment 195960.0 -322000.0 -0.86 197440.0 -195000.0 -0.54 -0.9872 -0.9743 3561897 PK04_181057 OC1CCC(CC1)N2C(C(=O)NCc3ccccc3)C4(OC5C=C4)C(C5C(=O)OCC=C)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C18 compound treatment 309800.0 -208000.0 -0.56 258130.0 -135000.0 -0.37 -0.6544 -0.9805 3057099 PK04_181058 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3ccco3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C19 compound treatment 297350.0 -220000.0 -0.59 228000.0 -165000.0 -0.45 -0.7364 -0.9916 3561892 PK04_181059 CCOC(=O)C1C2OC3(C=C2)C(N(CCCCCCO)C(=O)C13)C(=O)N(CC=C)Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C20 compound treatment 630200.0 112000.0 0.3 516610.0 124000.0 0.34 0.4525 0.9981 3057100 PK04_181060 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3ccco3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C21 compound treatment 710800.0 193000.0 0.52 530600.0 138000.0 0.38 0.6319 0.9883 3561898 PK04_181061 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=C[C@]42O[C@@H]5/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]4C1=O)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C22 compound treatment 600200.0 82500.0 0.22 232930.0 -160000.0 -0.44 -0.1549 -0.3152 3176076 PK04_181062 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C23 compound treatment 386720.0 -131000.0 -0.35 286370.0 -107000.0 -0.29 -0.4543 -0.996 3561899 PK04_181063 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 C24 compound treatment 387480.0 -130000.0 -0.35 207200.0 -186000.0 -0.51 -0.6066 -0.9826 2065566 PK04_181064 CCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D01 compound treatment 698640.0 181000.0 0.48 365400.0 -27500.0 -0.08 0.2882 0.5893 3561900 PK04_181065 COCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D02 compound treatment 659790.0 142000.0 0.38 326120.0 -66800.0 -0.18 0.1386 0.3289 3561901 PK04_181066 COc1cc(OC)c(CNS(=O)(=O)c2ccc(Br)cc2)c(OC)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D03 compound treatment 777410.0 260000.0 0.69 627080.0 234000.0 0.64 0.945 0.9993 3561902 PK04_181067 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D04 compound treatment 418800.0 -98900.0 -0.26 581970.0 189000.0 0.52 0.1801 0.3093 3561903 PK04_181068 COc1ccc(CN(C(COC(=O)c2cccc(OC)c2O)C=C)S(=O)(=O)c3ccc(Br)cc3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D05 compound treatment 342570.0 -175000.0 -0.47 207790.0 -185000.0 -0.51 -0.6903 -0.9991 3215593 PK04_181069 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D06 compound treatment 369680.0 -148000.0 -0.4 416830.0 23900.0 0.07 -0.2332 -0.5818 3561904 PK04_181070 COC(=O)C1CC=C(CC1C(=O)OC)N(Cc2ccc(OC)cc2)S(=O)(=O)c3ccc(Br)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D07 compound treatment 675570.0 158000.0 0.42 333960.0 -59000.0 -0.16 0.1836 0.4066 3561905 PK04_181071 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CN(C)Cc3ccccc3)CC(O2)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D08 compound treatment 408850.0 -109000.0 -0.29 359040.0 -33900.0 -0.09 -0.2715 -0.8889 3561906 PK04_181072 COc1ccc(CN([C@H](COC(=O)c2ccc(cc2)[N+](=O)[O-])C=C)S(=O)(=O)c3ccc(Br)cc3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D09 compound treatment 368760.0 -149000.0 -0.4 524190.0 131000.0 0.36 -0.0266 -0.0495 3561908 PK04_181073 OC(CSc1nc2ccccc2o1)CC(O)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D10 compound treatment 295290.0 -222000.0 -0.59 368480.0 -24400.0 -0.07 -0.4676 -0.782 3561909 PK04_181074 Brc1ccc(cc1)N2C(CN(C2=O)S(=O)(=O)c3ccc(Br)cc3)C=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D11 mock treatment 721980.0 204000.0 0.55 450080.0 57200.0 0.16 0.4967 0.875 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D12 mock treatment 706080.0 188000.0 0.5 386880.0 -6050.0 -0.02 0.344 0.6834 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D13 compound treatment 472760.0 -45000.0 -0.12 313660.0 -79300.0 -0.22 -0.2388 -0.9608 3561910 PK04_181075 COC(=O)CCCCCCC(=O)NOCc1ccccc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D14 compound treatment 323570.0 -194000.0 -0.52 309170.0 -83800.0 -0.23 -0.5293 -0.933 3561911 PK04_181076 COc1ccc(CN([C@H](CI)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D15 mock treatment 544480.0 26700.0 0.07 329440.0 -63500.0 -0.17 -0.0728 -0.3863 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D16 mock treatment 688850.0 171000.0 0.46 276810.0 -116000.0 -0.32 0.0977 0.1754 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D17 compound treatment 785570.0 268000.0 0.72 604190.0 211000.0 0.58 0.916 0.9946 3561913 PK04_181077 OC(=O)CCCCCCC(=O)NOCc1ccccc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D18 compound treatment 384500.0 -133000.0 -0.36 438690.0 45800.0 0.13 -0.1628 -0.4314 3561914 PK04_181078 COc1ccc(CN(C2=CCC3C(C2)C(=O)N(C)C3=O)S(=O)(=O)c4ccc(Br)cc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D19 compound treatment 754000.0 236000.0 0.63 197450.0 -195000.0 -0.54 0.0667 0.0805 3561915 PK04_181079 OCc1ccc(NC(=O)CCCCCCC(=O)NOCc2ccccc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D20 compound treatment 458600.0 -59100.0 -0.16 473710.0 80800.0 0.22 0.0451 0.1657 3561916 PK04_181080 COCCCN(CC(O)CO)C[C@]1(O)CCC2[C@]1(C)CCC3[C@@]4(C)CC[C@H](O)C[C@@]54C=C[C@]23C(=C5)C(=O)c6ccc(OC)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D21 compound treatment 726000.0 208000.0 0.56 600800.0 208000.0 0.57 0.7969 0.9999 3561917 PK04_181081 O=Cc1ccc(NC(=O)CCCCCCC(=O)NOCc2ccccc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D22 compound treatment 471680.0 -46100.0 -0.12 437220.0 44300.0 0.12 -0.001 -0.0059 3561918 PK04_181082 COCCCN(CC(O)CO)C[C@]1(O)CCC2C3=CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@@]21C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D23 compound treatment 426760.0 -91000.0 -0.24 359690.0 -33200.0 -0.09 -0.2364 -0.9105 3561919 PK04_181083 OC(CN=[N+]=[N-])CC(O)c1ccccc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 D24 compound treatment 308110.0 -210000.0 -0.56 242770.0 -150000.0 -0.41 -0.6874 -0.9887 3561920 PK04_181084 COCCCN(C[C@]1(O)CCC2C3=CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@@]21C)C(=O)O[C@H]5C[C@@H](C)CC[C@@H]5C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E01 mock treatment 716800.0 199000.0 0.53 679640.0 287000.0 0.79 0.9325 0.9817 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E02 mock treatment 519840.0 2090.0 0.01 652160.0 259000.0 0.71 0.5072 0.7126 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E03 compound treatment 793320.0 276000.0 0.74 326890.0 -66000.0 -0.18 0.3923 0.5175 3561899 PK04_181085 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E04 compound treatment 454640.0 -63100.0 -0.17 345760.0 -47200.0 -0.13 -0.2108 -0.9915 2065568 PK04_181086 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E05 compound treatment 798240.0 280000.0 0.75 427470.0 34500.0 0.09 0.5968 0.7903 3561899 PK04_181087 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E06 compound treatment 509920.0 -7830.0 -0.02 271360.0 -122000.0 -0.33 -0.2508 -0.7499 2065570 PK04_181088 O=C(NCc1ccccc1)C(COCc2ccccc2)OC(=O)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E07 compound treatment 430650.0 -87100.0 -0.23 439210.0 46300.0 0.13 -0.0746 -0.2816 3561899 PK04_181089 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E08 compound treatment 503320.0 -14400.0 -0.04 398960.0 6030.0 0.02 -0.0155 -0.3704 2065572 PK04_181090 COc1ccc(NC(=O)C(COCc2ccccc2)OC(=O)c3ccccc3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E09 mock treatment 740880.0 223000.0 0.6 575540.0 183000.0 0.5 0.7759 0.9963 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E10 mock treatment 478560.0 -39200.0 -0.1 559330.0 166000.0 0.46 0.249 0.5313 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E11 compound treatment 528400.0 10700.0 0.03 307300.0 -85600.0 -0.24 -0.1461 -0.617 3561921 PK04_181091 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E12 compound treatment 524800.0 7050.0 0.02 347620.0 -45300.0 -0.12 -0.0746 -0.5932 2065574 PK04_181092 CC(C)(C)NC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E13 compound treatment 333810.0 -184000.0 -0.49 350570.0 -42400.0 -0.12 -0.4296 -0.851 3561922 PK04_181093 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(Cc4ccc(OC)cc4)C(=O)[C@@H]13)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E14 compound treatment 284810.0 -233000.0 -0.62 401850.0 8920.0 0.02 -0.4226 -0.6787 2065576 PK04_181094 CCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E15 compound treatment 217500.0 -300000.0 -0.8 430920.0 38000.0 0.1 -0.4933 -0.61 3561841 PK04_181095 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E16 compound treatment 713710.0 196000.0 0.52 583520.0 191000.0 0.52 0.7401 1.0 2065599 PK04_181096 CCCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E17 mock treatment 290160.0 -228000.0 -0.61 586360.0 193000.0 0.53 -0.0543 -0.0673 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E18 mock treatment 346890.0 -171000.0 -0.46 496000.0 103000.0 0.28 -0.1226 -0.2283 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E19 compound treatment 716450.0 199000.0 0.53 260160.0 -133000.0 -0.36 0.1175 0.1826 3561841 PK04_181097 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E20 compound treatment 369250.0 -148000.0 -0.4 517280.0 124000.0 0.34 -0.0391 -0.0746 3561923 PK04_181098 CCCNC(=O)COc1ccc(C=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E21 compound treatment 274410.0 -243000.0 -0.65 277770.0 -115000.0 -0.32 -0.6831 -0.9452 3561841 PK04_181099 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E22 compound treatment 208320.0 -309000.0 -0.83 258400.0 -135000.0 -0.37 -0.8456 -0.9341 3561924 PK04_181100 CCCNC(=O)Cc1ccc(N)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E23 compound treatment 290080.0 -228000.0 -0.61 261920.0 -131000.0 -0.36 -0.6843 -0.9686 3561841 PK04_181101 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 E24 compound treatment 246780.0 -271000.0 -0.72 335360.0 -57600.0 -0.16 -0.6235 -0.8417 3561925 PK04_181102 CCOC(=O)/C=C/c1ccccc1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F01 mock treatment 820640.0 303000.0 0.81 260700.0 -132000.0 -0.36 0.3154 0.3557 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F02 mock treatment 658080.0 140000.0 0.37 235270.0 -158000.0 -0.43 -0.041 -0.0716 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F03 compound treatment 675680.0 158000.0 0.42 234440.0 -158000.0 -0.44 -0.0094 -0.0155 3561927 PK04_181103 OC(CSc1nc(c(o1)c2ccccc2)c3ccccc3)CC(O)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F04 compound treatment 429970.0 -87800.0 -0.23 401280.0 8350.0 0.02 -0.1496 -0.6349 1366116 PK04_181104 Brc1ccc2ncnc(NCC=C)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F05 compound treatment 244480.0 -273000.0 -0.73 543040.0 150000.0 0.41 -0.2247 -0.2681 3561928 PK04_181105 CN(CC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3)Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F06 compound treatment 219080.0 -299000.0 -0.8 343110.0 -49800.0 -0.14 -0.6608 -0.8164 1945167 PK04_181106 C/C(=C/C(=O)c1ccc(Cl)cc1)/Nc2cccc(O)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F07 compound treatment 497600.0 -20100.0 -0.05 563930.0 171000.0 0.47 0.2939 0.622 3561929 PK04_181107 OC(CSc1nc2ccccc2s1)CC(O)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F08 compound treatment 772160.0 254000.0 0.68 534080.0 141000.0 0.39 0.7545 0.9645 1448632 PK04_181108 Nn1cnc2-c3ccccc3CC4(CCCC4)c2c1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F09 mock treatment 335120.0 -183000.0 -0.49 472080.0 79200.0 0.22 -0.1913 -0.3582 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F10 mock treatment 267460.0 -250000.0 -0.67 367390.0 -25500.0 -0.07 -0.5223 -0.777 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F11 compound treatment 490080.0 -27700.0 -0.07 481730.0 88800.0 0.24 0.1201 0.4716 3561930 PK04_181109 OC(CSc1ccccn1)CC(O)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F12 compound treatment 255110.0 -263000.0 -0.7 489450.0 96500.0 0.26 -0.3087 -0.4116 3561931 PK04_181110 [O-][N+](=O)c1ccccc1/C=C/c2ccncc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F13 compound treatment 349710.0 -168000.0 -0.45 285920.0 -107000.0 -0.29 -0.5251 -0.9789 3561933 PK04_181111 ONC(=O)CCCCCCC(=O)NOCc1ccccc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F14 compound treatment 212640.0 -305000.0 -0.81 171880.0 -221000.0 -0.61 -1.0054 -0.9895 1679359 PK04_181112 OC(=O)CCCN1C(=O)CSC1=S 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F15 compound treatment 696370.0 179000.0 0.48 228350.0 -165000.0 -0.45 0.0179 0.0272 1020755 PK04_181113 O=C(C[n+]1ccc2ccccc2c1)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F16 compound treatment 206560.0 -311000.0 -0.83 343360.0 -49600.0 -0.14 -0.684 -0.8121 3561934 PK04_181114 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)O)C2=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F17 mock treatment 801120.0 283000.0 0.76 194080.0 -199000.0 -0.55 0.1492 0.1599 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F18 mock treatment 373230.0 -145000.0 -0.39 183400.0 -210000.0 -0.58 -0.6797 -0.9812 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F19 compound treatment 198980.0 -319000.0 -0.85 188800.0 -204000.0 -0.56 -0.9983 -0.9794 3561936 PK04_181115 Brc1c2OCOc2ccc1C[n+]3ccc4ccccc4c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F20 compound treatment 87640.0 -430000.0 -1.15 103620.0 -289000.0 -0.79 -1.374 -0.9838 3561937 PK04_181116 COc1ccc(cc1)S(=O)(=O)Nc2ccccc2/C=C/c3ccncc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F21 compound treatment 679580.0 162000.0 0.43 271440.0 -121000.0 -0.33 0.0698 0.1279 3561939 PK04_181117 CC(C)(C)[Si](C)(C)Oc1ccc2cc[n+](Cc3ccccc3Br)cc2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F22 compound treatment 558660.0 40900.0 0.11 241480.0 -151000.0 -0.42 -0.2167 -0.5041 1936946 PK04_181118 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F23 compound treatment 204160.0 -314000.0 -0.84 473410.0 80500.0 0.22 -0.436 -0.5033 3561940 PK04_181119 COc1ccc(Br)c(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 F24 compound treatment 611300.0 93600.0 0.25 247940.0 -145000.0 -0.4 -0.1048 -0.2229 3561941 PK04_181120 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)O)C2=O)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G01 compound treatment 594310.0 76600.0 0.2 645360.0 252000.0 0.69 0.6347 0.8783 3561841 PK04_181121 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G02 compound treatment 757330.0 240000.0 0.64 598300.0 205000.0 0.56 0.8512 0.998 3561943 PK04_181122 O=C1CSC(N1c2ccc(cc2)c3ccccc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G03 mock treatment 663590.0 146000.0 0.39 416640.0 23700.0 0.07 0.3215 0.814 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G04 mock treatment 769490.0 252000.0 0.67 253650.0 -139000.0 -0.38 0.2051 0.2651 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G05 compound treatment 287330.0 -230000.0 -0.62 433990.0 41100.0 0.11 -0.3555 -0.5681 PK04_181123 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G06 compound treatment 714970.0 197000.0 0.53 294570.0 -98400.0 -0.27 0.1815 0.3067 3561944 PK04_181124 CC(C)(C)c1ccc(cc1)N2C(SCC2=O)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G07 compound treatment 421480.0 -96300.0 -0.26 412410.0 19500.0 0.05 -0.144 -0.5483 PK04_181125 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G08 compound treatment 689030.0 171000.0 0.46 254240.0 -139000.0 -0.38 0.0543 0.0912 3561945 PK04_181126 CCOC(=O)/C=C(\C)/c1ccccc1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G09 compound treatment 286440.0 -231000.0 -0.62 285280.0 -108000.0 -0.3 -0.6458 -0.943 3561841 PK04_181127 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G10 compound treatment 725150.0 207000.0 0.55 376580.0 -16300.0 -0.04 0.36 0.6477 3561947 PK04_181128 CCOC(=O)/C=C/c1c(OC)cccc1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G11 compound treatment 381160.0 -137000.0 -0.36 219850.0 -173000.0 -0.48 -0.594 -0.9915 3561899 PK04_181129 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G12 compound treatment 668450.0 151000.0 0.4 539840.0 147000.0 0.4 0.5698 1.0 3561949 PK04_181130 CCCNC(=O)Cc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G13 compound treatment 587960.0 70200.0 0.19 141330.0 -252000.0 -0.69 -0.3558 -0.4971 3561950 PK04_181131 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)c6cccc(Cl)c6CO)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G14 compound treatment 395230.0 -123000.0 -0.33 502240.0 109000.0 0.3 -0.0192 -0.0432 3561952 PK04_181132 COc1cc(/C=C/CO)cc(OC)c1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G15 compound treatment 566990.0 49200.0 0.13 209790.0 -183000.0 -0.5 -0.2625 -0.5051 3561841 PK04_181133 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G16 compound treatment 362790.0 -155000.0 -0.41 562170.0 169000.0 0.46 0.0359 0.0577 3561954 PK04_181134 COc1ccccc1/C=C/CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G17 compound treatment 211210.0 -307000.0 -0.82 205170.0 -188000.0 -0.52 -0.9434 -0.9751 3561956 PK04_181135 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4cccc(Cl)c4CO)C(=O)N(CC=C)Cc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G18 compound treatment 421520.0 -96200.0 -0.26 550560.0 158000.0 0.43 0.1243 0.2469 3561958 PK04_181136 O=C1CS(=O)(=O)C(N1c2ccc(cc2)c3ccccc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G19 mock treatment 674240.0 156000.0 0.42 337860.0 -55100.0 -0.15 0.1887 0.4244 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G20 mock treatment 687000.0 169000.0 0.45 255250.0 -138000.0 -0.38 0.0524 0.0889 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G21 compound treatment 722690.0 205000.0 0.55 497890.0 105000.0 0.29 0.5908 0.9551 3561959 PK04_181137 CC(CO)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O[C@@H]([C@@H](C)N(C)C(=O)CCC=C)c5ccccc5)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G22 compound treatment 214410.0 -303000.0 -0.81 256320.0 -137000.0 -0.38 -0.8381 -0.9387 3561961 PK04_181138 CC(C)(C)c1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G23 compound treatment 384380.0 -133000.0 -0.36 393320.0 393.0 0.0 -0.2511 -0.705 3561959 PK04_181139 CC(CO)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O[C@@H]([C@@H](C)N(C)C(=O)CCC=C)c5ccccc5)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 G24 compound treatment 231260.0 -286000.0 -0.77 277120.0 -116000.0 -0.32 -0.7659 -0.9243 2093329 PK04_181140 COC(=O)/C=C/c1cc(OC)c(OC)c(OC)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H01 compound treatment 615620.0 97900.0 0.26 259580.0 -133000.0 -0.37 -0.074 -0.1645 3561962 PK04_181141 Brc1ccccc1C(=O)[n+]2ccc3ccccc3c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H02 compound treatment 451220.0 -66500.0 -0.18 174440.0 -218000.0 -0.6 -0.5498 -0.8788 3561963 PK04_181142 COc1ccccc1/C=C/2\SC(=S)N(CCCC(=O)O)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H03 mock treatment 768380.0 251000.0 0.67 195570.0 -197000.0 -0.54 0.0902 0.1048 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H04 mock treatment 844000.0 326000.0 0.87 249070.0 -144000.0 -0.39 0.3369 0.3521 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H05 compound treatment 309220.0 -209000.0 -0.56 135380.0 -258000.0 -0.71 -0.8938 -0.993 3561965 PK04_181143 COc1cc2CC[N+](=Cc2cc1O[Si](C)(C)C(C)(C)C)Cc3ccccc3Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H06 compound treatment 165370.0 -352000.0 -0.94 102950.0 -290000.0 -0.8 -1.2285 -0.9965 3561966 PK04_181144 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H07 compound treatment 903600.0 386000.0 1.03 693680.0 301000.0 0.83 1.3126 0.994 3561968 PK04_181145 COc1cc2CC[N+](=Cc2cc1OC)C(=O)c3ccccc3Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H08 compound treatment 353080.0 -165000.0 -0.44 226210.0 -167000.0 -0.46 -0.6347 -0.9998 3561969 PK04_181146 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3C4CC5CC(C4)CC3C5)C2=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H09 compound treatment 482590.0 -35200.0 -0.09 225450.0 -167000.0 -0.46 -0.3915 -0.8343 3561971 PK04_181147 Oc1ccc2CCN(Cc3ccccc3Br)C(C=C)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H10 compound treatment 530010.0 12300.0 0.03 372070.0 -20900.0 -0.06 -0.0173 -0.2627 3561972 PK04_181148 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(O)(C4)C3)C5)C2=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H11 compound treatment 467580.0 -50200.0 -0.13 497090.0 104000.0 0.29 0.1075 0.3403 3561974 PK04_181149 Brc1c[n+](Cc2ccccc2)cc3ccccc13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H12 compound treatment 601120.0 83400.0 0.22 471110.0 78200.0 0.21 0.3092 0.9998 3561975 PK04_181150 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NCC3(CC4CC5CC(C4)C3)C5)C2=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H13 compound treatment 162670.0 -355000.0 -0.95 128920.0 -264000.0 -0.72 -1.1831 -0.9912 3561977 PK04_181151 COc1ccc(Br)c(C[n+]2cc(Br)c3ccccc3c2)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H14 compound treatment 684530.0 167000.0 0.45 477500.0 84600.0 0.23 0.4792 0.9539 3561978 PK04_181152 COc1ccccc1/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H15 compound treatment 724800.0 207000.0 0.55 201600.0 -191000.0 -0.53 0.0196 0.0257 1003512 PK04_181153 C[n+]1ccc2ccccc2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H16 compound treatment 124250.0 -393000.0 -1.05 149970.0 -243000.0 -0.67 -1.2148 -0.9759 3561980 PK04_181154 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H17 compound treatment 537310.0 19600.0 0.05 180650.0 -212000.0 -0.58 -0.3751 -0.6411 1032420 PK04_181155 C(c1ccccc1)[n+]2ccc3ccccc3c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H18 compound treatment 291280.0 -226000.0 -0.6 198300.0 -195000.0 -0.53 -0.8056 -0.9981 3561982 PK04_181156 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H19 mock treatment 153920.0 -364000.0 -0.97 222470.0 -170000.0 -0.47 -1.0181 -0.9439 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H20 mock treatment 366640.0 -151000.0 -0.4 215080.0 -178000.0 -0.49 -0.6306 -0.9955 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H21 compound treatment 158850.0 -359000.0 -0.96 172670.0 -220000.0 -0.6 -1.1054 -0.9753 3561984 PK04_181157 COc1ccc(Br)c(C[n+]2ccc3ccccc3c2)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H22 compound treatment 31680.0 -486000.0 -1.3 27420.0 -366000.0 -1.0 -1.6276 -0.9919 3561985 PK04_181158 O=C1C=C[C@@H]2[C@@H]3C=C[C@H]([C@@H]2[C@]41CO4)[C@@]5(CO5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H23 compound treatment 19760.0 -498000.0 -1.33 22720.0 -370000.0 -1.02 -1.6592 -0.9912 3561987 PK04_181159 COc1ccc(Br)c(C[n+]2ccc3c(cccc3c2)[N+](=O)[O-])c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 H24 compound treatment 525830.0 8080.0 0.02 152490.0 -240000.0 -0.66 -0.4515 -0.6836 3561988 PK04_181160 CC1(C)C[C@H]2C[C@H]3C(=C[C@]2(CO1)C(=O)[C@@]43CO4)Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I01 compound treatment 549920.0 32200.0 0.09 314330.0 -78600.0 -0.22 -0.0918 -0.3953 3561956 PK04_181161 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4cccc(Cl)c4CO)C(=O)N(CC=C)Cc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I02 compound treatment 766400.0 249000.0 0.66 522030.0 129000.0 0.35 0.7203 0.9568 3561990 PK04_181162 CCCNC(=O)Cc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I03 compound treatment 381340.0 -136000.0 -0.36 409250.0 16300.0 0.04 -0.2259 -0.6155 3561991 PK04_181163 OCc1c(Cl)cccc1N2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OCC=C)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I04 compound treatment 749700.0 232000.0 0.62 253670.0 -139000.0 -0.38 0.1677 0.2304 3561993 PK04_181164 COc1ccccc1/C(=C/CO)/C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I05 mock treatment 791680.0 274000.0 0.73 289380.0 -104000.0 -0.28 0.3164 0.403 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I06 mock treatment 331850.0 -186000.0 -0.5 308980.0 -83900.0 -0.23 -0.5141 -0.9391 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I07 compound treatment 308510.0 -209000.0 -0.56 482290.0 89400.0 0.25 -0.2217 -0.3632 3561995 PK04_181165 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I08 compound treatment 659840.0 142000.0 0.38 442010.0 49100.0 0.13 0.3637 0.9029 3561996 PK04_181166 COc1ccccc1/C(=C/C=O)/C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I09 compound treatment 260160.0 -258000.0 -0.69 133560.0 -259000.0 -0.71 -0.99 -0.9999 3561998 PK04_181167 OCc1c(Cl)cccc1N2[C@@H](C(=O)NCc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)O)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I10 compound treatment 216540.0 -301000.0 -0.8 125470.0 -267000.0 -0.73 -1.0881 -0.999 2069262 PK04_181168 COc1cc(/C=C/C=O)cc(OC)c1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I11 compound treatment 171070.0 -347000.0 -0.93 643530.0 251000.0 0.69 -0.1683 -0.1459 3562000 PK04_181169 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4ccccc4Cl)C(=O)N(CC=C)Cc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I12 compound treatment 174010.0 -344000.0 -0.92 638260.0 245000.0 0.67 -0.1729 -0.1519 3562002 PK04_181170 CCOC(=O)/C=C/c1cccc(c1)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I13 compound treatment 190900.0 -327000.0 -0.87 202370.0 -191000.0 -0.52 -0.9872 -0.97 3562003 PK04_181171 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3C(=O)N(Cc4ccccc4)[C@@H]5C(=O)N(Cc6ccccc6)CC=C[C@]35O[C@@H]2/C=C/CCC(=O)N1C)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I14 compound treatment 229970.0 -288000.0 -0.77 496910.0 104000.0 0.29 -0.3417 -0.4167 3562005 PK04_181172 COc1cccc(OC)c1/C=C/CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I15 compound treatment 349000.0 -169000.0 -0.45 150760.0 -242000.0 -0.66 -0.7888 -0.9821 3562007 PK04_181173 CCCCNC(=O)[C@@H]1N(C2CCCCC2)C(=O)[C@H]3[C@@H]([C@H]4O[C@@]13C=C4)C(=O)OCC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I16 compound treatment 205190.0 -313000.0 -0.83 194010.0 -199000.0 -0.55 -0.9765 -0.9788 3562009 PK04_181174 Clc1cccc(c1)N2C(SCC2=O)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I17 compound treatment 215320.0 -302000.0 -0.81 223150.0 -170000.0 -0.47 -0.9008 -0.9659 3561995 PK04_181175 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I18 compound treatment 373920.0 -144000.0 -0.38 524360.0 131000.0 0.36 -0.0165 -0.0313 3065130 PK04_181176 Clc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I19 compound treatment 273870.0 -244000.0 -0.65 202690.0 -190000.0 -0.52 -0.8299 -0.994 3562010 PK04_181177 C[C@H]([C@H](OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4)c5ccccc5)N(C)C(=O)CCC=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I20 compound treatment 659230.0 141000.0 0.38 582400.0 189000.0 0.52 0.635 0.9877 3562012 PK04_181178 OC/C=C/c1cccc(c1)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I21 mock treatment 260490.0 -257000.0 -0.69 584370.0 191000.0 0.53 -0.1142 -0.132 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I22 mock treatment 350560.0 -167000.0 -0.45 174190.0 -219000.0 -0.6 -0.7404 -0.9894 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I23 compound treatment 497050.0 -20700.0 -0.06 254310.0 -139000.0 -0.38 -0.3082 -0.8014 3562014 PK04_181179 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3C(=O)N([C@@H]4C(=O)N(Cc5ccccc5)CC=C[C@]34O[C@@H]2/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 I24 compound treatment 663840.0 146000.0 0.39 258900.0 -134000.0 -0.37 0.0157 0.0293 3215604 PK04_181180 O=C/1N(C(c2ccccc2)S(=O)(=O)\C1=C/c3ccc4ccccc4c3)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J01 compound treatment 577540.0 59800.0 0.16 178340.0 -215000.0 -0.59 -0.3036 -0.4975 3562016 PK04_181181 COc1ccc(Br)c(C[n+]2ccccc2C)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J02 compound treatment 475090.0 -42700.0 -0.11 140440.0 -252000.0 -0.69 -0.5707 -0.8124 3562017 PK04_181182 OCCCCCCO[C@H]1C[C@H]2C(=C[C@]1(Br)C(=O)[C@@]32CO3)Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J03 compound treatment 181530.0 -336000.0 -0.9 265980.0 -127000.0 -0.35 -0.8814 -0.915 3562019 PK04_181183 COc1ccc(Br)c(C[n+]2ccc3ccccc3c2C)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J04 compound treatment 311530.0 -206000.0 -0.55 207430.0 -185000.0 -0.51 -0.7496 -0.9992 3562020 PK04_181184 OCCCCO[C@H]1C[C@H]2C(=C[C@]1(Br)C(=O)[C@@]32CO3)Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J05 mock treatment 242830.0 -275000.0 -0.73 188800.0 -204000.0 -0.56 -0.9155 -0.9911 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J06 mock treatment 178920.0 -339000.0 -0.9 168490.0 -224000.0 -0.62 -1.0756 -0.9824 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J07 compound treatment 306720.0 -211000.0 -0.56 243040.0 -150000.0 -0.41 -0.6895 -0.988 3562022 PK04_181185 Cc1[n+](Cc2ccccc2)ccc3ccccc13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J08 compound treatment 109640.0 -408000.0 -1.09 99800.0 -293000.0 -0.8 -1.3398 -0.9889 3562023 PK04_181186 BrC1=C[C@@]2(Br)[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J09 compound treatment 186400.0 -331000.0 -0.89 198510.0 -194000.0 -0.53 -1.0032 -0.9707 3562025 PK04_181187 COc1ccc(Br)c(C[n+]2cccc3cc(OC)ccc23)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J10 compound treatment 101330.0 -416000.0 -1.11 91840.0 -301000.0 -0.83 -1.371 -0.9893 3562026 PK04_181188 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@]2(Br)C(=O)[C@@]43CO4)Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J11 compound treatment 627060.0 109000.0 0.29 274920.0 -118000.0 -0.32 -0.0226 -0.0519 3562028 PK04_181189 COc1ccc(Br)c(C[N+]2=C(C)CCC2)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J12 compound treatment 336220.0 -182000.0 -0.48 248850.0 -144000.0 -0.4 -0.6225 -0.9949 3562029 PK04_181190 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccccc4)c5cc(ccc5F)[N+](=O)[O-])cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J13 compound treatment 183360.0 -334000.0 -0.89 622880.0 230000.0 0.63 -0.1851 -0.1693 3562031 PK04_181191 COc1ccc(Br)c(CN2CCc3cc(OC)c(OC)cc3C2C#Cc4ccccc4)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J14 compound treatment 575760.0 58000.0 0.15 447050.0 54100.0 0.15 0.2146 0.9998 3562032 PK04_181192 COc1ccc(CCNC(=O)[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccccc4)c5cc(ccc5F)[N+](=O)[O-])cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J15 compound treatment 183410.0 -334000.0 -0.89 172240.0 -221000.0 -0.61 -1.0599 -0.9821 3562033 PK04_181193 COC(CN(Cc1cccc(OC)c1)S(=O)(=O)c2ccc(C)cc2)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J16 compound treatment 288490.0 -229000.0 -0.61 326820.0 -66100.0 -0.18 -0.5613 -0.8789 3562034 PK04_181194 COc1ccc(CCN2C(=O)C3(CC(=O)N(Cc4ccccc4)C3c5ccccc5)c6cc(ccc26)[N+](=O)[O-])cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J17 compound treatment 275210.0 -243000.0 -0.65 161960.0 -231000.0 -0.63 -0.9065 -0.9999 3562035 PK04_181195 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J18 compound treatment 672770.0 155000.0 0.41 551250.0 158000.0 0.43 0.6001 0.9997 3562036 PK04_181196 C[C@@]1(CCc2ccccc2)C[C@@H](C[Si](C)(C)C(c3ccccc3)c4ccccc4)OO1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J19 compound treatment 546720.0 29000.0 0.08 224040.0 -169000.0 -0.46 -0.2731 -0.581 3562038 PK04_181197 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C#Cc4ccccc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J20 compound treatment 708250.0 191000.0 0.51 369120.0 -23800.0 -0.07 0.3136 0.6113 3562039 PK04_181198 CCCCCCC1C[C@]2(CC[C@@H](CC2)C(C)(C)C)OO1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J21 mock treatment 607040.0 89300.0 0.24 301990.0 -90900.0 -0.25 -0.0079 -0.0229 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J22 mock treatment 619430.0 102000.0 0.27 588530.0 196000.0 0.54 0.5718 0.9501 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J23 compound treatment 270880.0 -247000.0 -0.66 233160.0 -160000.0 -0.44 -0.7764 -0.9804 3562041 PK04_181199 COc1cc2CCN(CC=C)C(C#Cc3ccccc3)c2cc1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 J24 compound treatment 237190.0 -281000.0 -0.75 343680.0 -49200.0 -0.14 -0.6255 -0.8214 3562042 PK04_181200 Cc1ccc(cc1)C2C[C@]3(CC[C@@H](CC3)C(C)(C)C)OO2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K01 compound treatment 501720.0 -16000.0 -0.04 427790.0 34900.0 0.1 0.0374 0.3568 3562010 PK04_181201 C[C@H]([C@H](OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4)c5ccccc5)N(C)C(=O)CCC=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K02 compound treatment 817790.0 300000.0 0.8 214250.0 -179000.0 -0.49 0.2198 0.2339 3215602 PK04_181202 Cc1c(NC(=O)/C(=C/c2ccc3ccccc3c2)/C#N)c(=O)n(c4ccccc4)n1C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K03 compound treatment 204680.0 -313000.0 -0.84 393790.0 863.0 0.0 -0.5896 -0.7051 3562044 PK04_181203 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K04 compound treatment 506100.0 -11600.0 -0.03 522400.0 129000.0 0.36 0.2294 0.6428 3562046 PK04_181204 COc1cccc(OC)c1/C=C/C=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K05 compound treatment 328130.0 -190000.0 -0.51 632680.0 240000.0 0.66 0.1073 0.1292 2065615 PK04_181205 COc1ccc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K06 compound treatment 685070.0 167000.0 0.45 190530.0 -202000.0 -0.56 -0.0769 -0.1078 3562048 PK04_181206 Clc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K07 mock treatment 704700.0 187000.0 0.5 268360.0 -125000.0 -0.34 0.1113 0.1838 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K08 mock treatment 563910.0 46200.0 0.12 200270.0 -193000.0 -0.53 -0.2868 -0.5281 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K09 compound treatment 185060.0 -333000.0 -0.89 341280.0 -51600.0 -0.14 -0.7286 -0.8097 3562049 PK04_181207 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC=C)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K10 compound treatment 639690.0 122000.0 0.33 101470.0 -291000.0 -0.8 -0.3355 -0.3883 3562051 PK04_181208 Clc1cccc(c1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K11 compound treatment 234510.0 -283000.0 -0.76 205350.0 -188000.0 -0.51 -0.8991 -0.9824 3562052 PK04_181209 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K12 compound treatment 341310.0 -176000.0 -0.47 239490.0 -153000.0 -0.42 -0.6311 -0.9984 3562054 PK04_181210 O=C1CSCN1c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K13 compound treatment 386260.0 -131000.0 -0.35 132800.0 -260000.0 -0.71 -0.7533 -0.9466 3562052 PK04_181211 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K14 compound treatment 887920.0 370000.0 0.99 603460.0 211000.0 0.58 1.1078 0.9673 1951450 PK04_181212 Cc1c(N2C(SCC2=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K15 mock treatment 294990.0 -223000.0 -0.59 289150.0 -104000.0 -0.28 -0.6222 -0.9432 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K16 mock treatment 256010.0 -262000.0 -0.7 155910.0 -237000.0 -0.65 -0.9545 -0.9994 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K17 compound treatment 443960.0 -73800.0 -0.2 306480.0 -86400.0 -0.24 -0.3072 -0.9957 3562052 PK04_181213 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K18 compound treatment 710360.0 193000.0 0.51 185060.0 -208000.0 -0.57 -0.0398 -0.0517 3562055 PK04_181214 CN1C(SCC1=O)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K19 compound treatment 487000.0 -30700.0 -0.08 627160.0 234000.0 0.64 0.3966 0.6118 3562056 PK04_181215 COCOc1ccc2cc(Br)ccc2c1c3c(OCOC)ccc4cc(Br)ccc34 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K20 compound treatment 760400.0 243000.0 0.65 235280.0 -158000.0 -0.43 0.1523 0.1954 3562057 PK04_181216 O=C1CS(=O)(=O)CN1c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K21 compound treatment 320280.0 -197000.0 -0.53 183430.0 -209000.0 -0.58 -0.7796 -0.9991 3220192 PK04_181217 CC(CO)N1C2C(=O)N(Cc3ccccc3)CC=CC42OC5C=CCOC(=O)C5C4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K22 compound treatment 436290.0 -81500.0 -0.22 220860.0 -172000.0 -0.47 -0.4879 -0.9381 3562058 PK04_181218 CN1C(c2ccccc2)S(=O)(=O)CC1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K23 mock treatment 282040.0 -236000.0 -0.63 616170.0 223000.0 0.61 -0.0118 -0.0134 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 K24 mock treatment 508540.0 -9210.0 -0.02 190300.0 -203000.0 -0.56 -0.4107 -0.7376 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L01 compound treatment 532160.0 14400.0 0.04 537880.0 145000.0 0.4 0.3086 0.7719 3562059 PK04_181219 COc1cc2CC[N+](=Cc2cc1OC)Cc3ccc(Br)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L02 compound treatment 747430.0 230000.0 0.61 649220.0 256000.0 0.7 0.9313 0.9977 3562060 PK04_181220 CCOC(=O)CCC1(C)C[C@]2(CC[C@@H](CC2)C(C)(C)C)OO1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L03 compound treatment 288130.0 -230000.0 -0.61 104760.0 -288000.0 -0.79 -0.9931 -0.9921 3562062 PK04_181221 Cc1cc2ccccc2c[n+]1CCCC=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L04 compound treatment 128650.0 -389000.0 -1.04 51860.0 -341000.0 -0.94 -1.397 -0.9986 3562063 PK04_181222 CC1(CCc2ccccc2)CC(CO)OO1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L05 compound treatment 152960.0 -365000.0 -0.97 227410.0 -166000.0 -0.45 -1.0103 -0.9397 3562064 PK04_181223 COc1ccc(Br)c(C[n+]2cc3ccccc3cc2C)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L06 compound treatment 207700.0 -310000.0 -0.83 459490.0 66600.0 0.18 -0.4564 -0.5381 3562065 PK04_181224 CC(C)(C)[C@H]1CC[C@]2(CC(C)(CC(C)(C)CO)OO2)CC1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L07 mock treatment 812160.0 294000.0 0.79 493570.0 101000.0 0.28 0.7514 0.9015 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L08 mock treatment 303680.0 -214000.0 -0.57 697510.0 305000.0 0.84 0.187 0.1846 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L09 compound treatment 328340.0 -189000.0 -0.51 531720.0 139000.0 0.38 -0.0883 -0.1394 3562067 PK04_181225 CC1=[N+](C)C2C3CC=CC3C1c4ccccc24 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L10 compound treatment 171200.0 -347000.0 -0.93 286760.0 -106000.0 -0.29 -0.8606 -0.8868 3562068 PK04_181226 CC(C)(C)[C@H]1CC[C@]2(CC(C)(CCO)OO2)CC1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L11 compound treatment 569340.0 51600.0 0.14 338370.0 -54600.0 -0.15 -0.0085 -0.0416 1006359 PK04_181227 Cc1cccc[n+]1C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L12 compound treatment 242720.0 -275000.0 -0.73 180710.0 -212000.0 -0.58 -0.9314 -0.9934 3562070 PK04_181228 CC1(CCOCc2ccccc2)CC(C)(CCc3ccccc3)OO1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L13 compound treatment 720480.0 203000.0 0.54 428240.0 35300.0 0.1 0.4515 0.8207 3562071 PK04_181229 C[n+]1cc2ccccc2cc1C#N 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L14 compound treatment 371310.0 -146000.0 -0.39 246610.0 -146000.0 -0.4 -0.5606 -0.9999 3562072 PK04_181230 COc1ccc(CN/2C(C3CC3)c4ccccc4C\C2=N\P(=O)(Oc5ccccc5)Oc6ccccc6)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L15 mock treatment 321090.0 -197000.0 -0.53 536500.0 144000.0 0.39 -0.0927 -0.1412 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L16 mock treatment 515220.0 -2530.0 -0.01 328610.0 -64300.0 -0.18 -0.1296 -0.7336 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L17 compound treatment 347890.0 -170000.0 -0.45 558900.0 166000.0 0.46 0.0014 0.0022 3562074 PK04_181231 CCCCOC1CC2[N+](=C(C)C1c3ccccc23)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L18 compound treatment 359650.0 -158000.0 -0.42 262400.0 -131000.0 -0.36 -0.552 -0.9967 3562075 PK04_181232 CCCCCCC1C[C@]2(CCC[C@@H](C)C2)OO1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L19 compound treatment 348220.0 -170000.0 -0.45 481170.0 88200.0 0.24 -0.1489 -0.2899 3188663 PK04_181233 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L20 compound treatment 314400.0 -203000.0 -0.54 165760.0 -227000.0 -0.62 -0.8251 -0.9976 3562077 PK04_181234 CC1(CCO)CC(C)(CCc2ccccc2)OO1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L21 compound treatment 711390.0 194000.0 0.52 542110.0 149000.0 0.41 0.6553 0.9933 3070955 PK04_181235 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L22 compound treatment 208910.0 -309000.0 -0.82 175280.0 -218000.0 -0.6 -1.0058 -0.9875 3562078 PK04_181236 COC(=O)CC1(C)CC(C)(CCc2ccccc2)OO1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L23 mock treatment 690880.0 173000.0 0.46 671650.0 279000.0 0.77 0.8681 0.9709 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 L24 mock treatment 589350.0 71600.0 0.19 788030.0 395000.0 1.08 0.9023 0.8191 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M01 compound treatment 208980.0 -309000.0 -0.82 399700.0 6770.0 0.02 -0.57 -0.691 3562079 PK04_181237 CC(C)(C)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C\COC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M02 compound treatment 216040.0 -302000.0 -0.81 236510.0 -156000.0 -0.43 -0.8735 -0.9566 3562081 PK04_181238 Clc1ccccc1/C=C/C=C\2/C(=O)N(CS2(=O)=O)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M03 compound treatment 207560.0 -310000.0 -0.83 157980.0 -235000.0 -0.65 -1.0419 -0.9923 3562049 PK04_181239 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC=C)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M04 compound treatment 29970.0 -488000.0 -1.3 39630.0 -353000.0 -0.97 -1.6071 -0.9894 3562083 PK04_181240 CN1C(c2ccccc2)S(=O)(=O)/C(=C\C=C\c3ccccc3Cl)/C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M05 compound treatment 185310.0 -332000.0 -0.89 157780.0 -235000.0 -0.65 -1.0844 -0.9877 3562085 PK04_181241 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M06 compound treatment 380880.0 -137000.0 -0.37 621180.0 228000.0 0.63 0.1846 0.2545 1053847 PK04_181242 O=C1CSC(N1c2ccccc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M07 compound treatment 639010.0 121000.0 0.32 613620.0 221000.0 0.61 0.6575 0.957 3562085 PK04_181243 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M08 compound treatment 179550.0 -338000.0 -0.9 299840.0 -93100.0 -0.26 -0.8195 -0.8729 3562087 PK04_181244 COc1ccccc1/C=C/C=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M09 mock treatment 348670.0 -169000.0 -0.45 345080.0 -47800.0 -0.13 -0.4122 -0.8765 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M10 mock treatment 486970.0 -30800.0 -0.08 179200.0 -214000.0 -0.59 -0.473 -0.7984 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M11 compound treatment 402080.0 -116000.0 -0.31 246780.0 -146000.0 -0.4 -0.5022 -0.9917 3562085 PK04_181245 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M12 compound treatment 519080.0 1330.0 0.0 211940.0 -181000.0 -0.5 -0.3488 -0.702 3562088 PK04_181246 O=C1CS(=O)(=O)C(N1c2ccccc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M13 mock treatment 470930.0 -46800.0 -0.13 580060.0 187000.0 0.51 0.2749 0.5198 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M14 mock treatment 445530.0 -72200.0 -0.19 593180.0 200000.0 0.55 0.2524 0.4331 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M15 compound treatment 271140.0 -247000.0 -0.66 141150.0 -252000.0 -0.69 -0.9545 -0.9997 3562089 PK04_181247 CCCCCNC(=O)[C@@H]1N(C(=O)[C@H]2[C@@H]([C@H]3O[C@@]12C=C3)C(=O)OCC)c4ccccc4Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M16 compound treatment 55790.0 -462000.0 -1.23 70950.0 -322000.0 -0.88 -1.4975 -0.9866 2118235 PK04_181248 [O-][N+](=O)c1cccc(/C=C/C=O)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M17 compound treatment 265980.0 -252000.0 -0.67 448770.0 55800.0 0.15 -0.3671 -0.5322 3562089 PK04_181249 CCCCCNC(=O)[C@@H]1N(C(=O)[C@H]2[C@@H]([C@H]3O[C@@]12C=C3)C(=O)OCC)c4ccccc4Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M18 compound treatment 222410.0 -295000.0 -0.79 581440.0 189000.0 0.52 -0.1918 -0.2033 3562090 PK04_181250 CC(C)Cc1ccc(/C=C/C=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M19 compound treatment 275100.0 -243000.0 -0.65 342170.0 -50800.0 -0.14 -0.5568 -0.8399 3561852 PK04_181251 CCOC(=O)C1C2OC3(C=C2)C(N(C(=O)C13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M20 compound treatment 510410.0 -7340.0 -0.02 317440.0 -75500.0 -0.21 -0.1604 -0.7705 3215597 PK04_181252 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3cccc(c3)[N+](=O)[O-])S2(=O)=O)c4cc(C)cc(C)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M21 compound treatment 359770.0 -158000.0 -0.42 229150.0 -164000.0 -0.45 -0.6163 -0.9995 3562092 PK04_181253 O=C1C2C3C(OC42C=CCN(Cc5ccccc5)C(=O)C4N1C6CCCCC6)C=CCOC3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M22 compound treatment 663840.0 146000.0 0.39 612190.0 219000.0 0.6 0.7016 0.978 3562093 PK04_181254 CCOc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M23 compound treatment 196160.0 -322000.0 -0.86 206440.0 -186000.0 -0.51 -0.9694 -0.9694 3562094 PK04_181255 O=C1C2C3C4OC2(C=C4)C(N1C5CCCCC5)C(=O)N(Cc6ccccc6)CCCCOC3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 M24 compound treatment 220320.0 -297000.0 -0.79 637870.0 245000.0 0.67 -0.0862 -0.0828 3562095 PK04_181256 Cc1cc(C)cc(c1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N01 compound treatment 583010.0 65300.0 0.17 396480.0 3550.0 0.01 0.1302 0.7455 3188533 PK04_181257 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N02 compound treatment 653150.0 135000.0 0.36 556290.0 163000.0 0.45 0.5729 0.9943 3562096 PK04_181258 CC1(CCc2ccccc2)CC(C)(CC(=O)O)OO1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N03 compound treatment 552550.0 34800.0 0.09 743860.0 351000.0 0.96 0.747 0.7717 3562097 PK04_181259 C=C/C=C/[C@H]1[C@@H]2[C@H](Cc3ccccc3)OC(=O)[C@H](Cc4ccccc4)N2CC1=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N04 compound treatment 612420.0 94700.0 0.25 600670.0 208000.0 0.57 0.5821 0.933 3562099 PK04_181260 CC1(CCOCc2ccccc2)CC(C)(COCc3ccccc3)OO1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N05 compound treatment 718010.0 200000.0 0.53 678980.0 286000.0 0.79 0.9335 0.9825 3562100 PK04_181261 Cn1c(=O)n2[C@H]3[C@@H]4[C@H](Cc5ccccc5)OC(=O)[C@H](Cc6ccccc6)N4CC3=C[C@@H](C7CC7)n2c1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N06 compound treatment 397440.0 -120000.0 -0.32 305600.0 -87300.0 -0.24 -0.3967 -0.9896 3562102 PK04_181262 C[C@@H]1CCC[C@]2(CC(C)(CCOCc3ccccc3)OO2)C1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N07 compound treatment 646490.0 129000.0 0.34 529570.0 137000.0 0.38 0.5084 0.9991 3562104 PK04_181263 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3[C@H]1Cc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N08 compound treatment 430810.0 -86900.0 -0.23 644160.0 251000.0 0.69 0.3235 0.4445 3562106 PK04_181264 CC1(C)O[C@]2(C)CC[C@@H]1OO2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N09 mock treatment 525440.0 7690.0 0.02 513050.0 120000.0 0.33 0.2477 0.7497 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N10 mock treatment 690190.0 172000.0 0.46 307040.0 -85900.0 -0.24 0.159 0.3072 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N11 compound treatment 373120.0 -145000.0 -0.39 466320.0 73400.0 0.2 -0.1307 -0.2999 3188666 PK04_181265 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N12 compound treatment 716720.0 199000.0 0.53 665760.0 273000.0 0.75 0.9054 0.9859 3562108 PK04_181266 CC[C@]1(CC[C@@H]2OO1)OC2(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N13 mock treatment 771930.0 254000.0 0.68 397390.0 4460.0 0.01 0.4887 0.7198 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N14 mock treatment 754000.0 236000.0 0.63 672190.0 279000.0 0.77 0.9883 0.9953 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N15 compound treatment 298030.0 -220000.0 -0.59 176230.0 -217000.0 -0.59 -0.8356 -1.0 3188536 PK04_181267 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N16 compound treatment 450850.0 -66900.0 -0.18 725190.0 332000.0 0.91 0.5187 0.558 3562110 PK04_181268 CCC[C@]1(CC[C@@H]2OO1)OC2(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N17 compound treatment 556100.0 38400.0 0.1 276120.0 -117000.0 -0.32 -0.1543 -0.4584 3188535 PK04_181269 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N18 compound treatment 189780.0 -328000.0 -0.88 388160.0 -4770.0 -0.01 -0.6287 -0.7176 3562112 PK04_181270 CC1(C)O[C@]2(CCc3ccccc3)CC[C@@H]1OO2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N19 compound treatment 287490.0 -230000.0 -0.62 237610.0 -155000.0 -0.43 -0.7364 -0.984 3070940 PK04_181271 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N20 compound treatment 196910.0 -321000.0 -0.86 170810.0 -222000.0 -0.61 -1.0372 -0.9861 3562114 PK04_181272 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N21 compound treatment 184410.0 -333000.0 -0.89 289380.0 -104000.0 -0.28 -0.8306 -0.8887 3188534 PK04_181273 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N22 compound treatment 428930.0 -88800.0 -0.24 469320.0 76400.0 0.21 -0.0194 -0.0614 3562115 PK04_181274 CC(C)(C)[C@H]1CC[C@]2(CC(C[Si](C)(C)C)OO2)CC1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N23 compound treatment 523630.0 5880.0 0.02 588720.0 196000.0 0.54 0.3912 0.7275 3562117 PK04_181275 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@H](C4CC4)n5n([C@@H]3[C@H]2[C@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 N24 compound treatment 416210.0 -102000.0 -0.27 298990.0 -93900.0 -0.26 -0.3741 -0.9997 1004341 PK04_181276 c1ccc2cnccc2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O01 compound treatment 399090.0 -119000.0 -0.32 370960.0 -22000.0 -0.06 -0.2667 -0.8268 3562118 PK04_181277 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)c4cccc(Cl)c4CO)C(=O)NCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O02 compound treatment 127940.0 -390000.0 -1.04 166720.0 -226000.0 -0.62 -1.1754 -0.9695 3562120 PK04_181278 CCOc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O03 compound treatment 583410.0 65700.0 0.18 496260.0 103000.0 0.28 0.3246 0.9733 3562122 PK04_181279 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O04 compound treatment 129710.0 -388000.0 -1.04 108240.0 -285000.0 -0.78 -1.2855 -0.9903 3562124 PK04_181280 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3cccc(c3)[N+](=O)[O-])S2(=O)=O)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O05 compound treatment 535080.0 17300.0 0.05 240720.0 -152000.0 -0.42 -0.2627 -0.6249 3562122 PK04_181281 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O06 compound treatment 120930.0 -397000.0 -1.06 169070.0 -224000.0 -0.61 -1.184 -0.9664 3562126 PK04_181282 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3ccccc3)S2(=O)=O)c4cc(C)cc(C)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O07 compound treatment 94840.0 -423000.0 -1.13 92510.0 -300000.0 -0.82 -1.3819 -0.9881 3562128 PK04_181283 CCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)C(C)(C)C)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O08 compound treatment 122790.0 -395000.0 -1.05 189210.0 -204000.0 -0.56 -1.1414 -0.956 3215600 PK04_181284 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3ccccc3)S2(=O)=O)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O09 compound treatment 17830.0 -500000.0 -1.34 72030.0 -321000.0 -0.88 -1.5671 -0.9796 3562128 PK04_181285 CCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)C(C)(C)C)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O10 compound treatment 356990.0 -161000.0 -0.43 429070.0 36100.0 0.1 -0.2335 -0.5297 3562130 PK04_181286 OCCSCC(O)CC(O)c1ccccc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O11 mock treatment 363390.0 -154000.0 -0.41 483950.0 91000.0 0.25 -0.1148 -0.2382 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O12 mock treatment 264590.0 -253000.0 -0.68 189450.0 -203000.0 -0.56 -0.8731 -0.9955 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O13 compound treatment 628450.0 111000.0 0.3 523860.0 131000.0 0.36 0.4633 0.9953 3561848 PK04_181287 CCCCCN1C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C1=O)c5ccccc5Cl)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O14 compound treatment 386260.0 -131000.0 -0.35 314180.0 -78700.0 -0.22 -0.4012 -0.9728 3562131 PK04_181288 OC(CSc1ccncc1)CC(O)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O15 compound treatment 258750.0 -259000.0 -0.69 467040.0 74100.0 0.2 -0.3453 -0.4788 3562132 PK04_181289 C[C@H](C(O)c1ccccc1)N(C)C(=O)CCC=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O16 compound treatment 351640.0 -166000.0 -0.44 297470.0 -95500.0 -0.26 -0.499 -0.9685 3562134 PK04_181290 COC(=O)CCCCCCC(=O)Nc1ccc(C=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O17 compound treatment 213730.0 -304000.0 -0.81 267280.0 -126000.0 -0.34 -0.8181 -0.9273 3562132 PK04_181291 C[C@H](C(O)c1ccccc1)N(C)C(=O)CCC=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O18 compound treatment 608120.0 90400.0 0.24 568860.0 176000.0 0.48 0.5122 0.9486 3562135 PK04_181292 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccccn3)CC(O2)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O19 compound treatment 366570.0 -151000.0 -0.4 259470.0 -133000.0 -0.37 -0.5446 -0.9988 3561921 PK04_181293 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O20 compound treatment 428110.0 -89600.0 -0.24 290030.0 -103000.0 -0.28 -0.369 -0.9966 3562136 PK04_181294 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc4ccccc4s3)CC(O2)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O21 compound treatment 275200.0 -243000.0 -0.65 257080.0 -136000.0 -0.37 -0.7218 -0.9656 3561921 PK04_181295 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O22 compound treatment 229300.0 -288000.0 -0.77 367760.0 -25200.0 -0.07 -0.5936 -0.7674 3562137 PK04_181296 OC(CC=C)c1ccc(cc1)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O23 compound treatment 220600.0 -297000.0 -0.79 432600.0 39700.0 0.11 -0.4842 -0.6044 3561921 PK04_181297 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 O24 compound treatment 293720.0 -224000.0 -0.6 325930.0 -67000.0 -0.18 -0.5532 -0.8837 3562138 PK04_181298 CC(C)(C)OC(=O)OC(CC=C)c1ccccc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P01 compound treatment 185410.0 -332000.0 -0.89 216670.0 -176000.0 -0.48 -0.9698 -0.9593 3562139 PK04_181299 COC(=O)C1(CCCCC1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P02 compound treatment 332550.0 -185000.0 -0.49 456020.0 63100.0 0.17 -0.2273 -0.4337 1015751 PK04_181300 Cc1ccncc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P03 compound treatment 341120.0 -177000.0 -0.47 180690.0 -212000.0 -0.58 -0.7456 -0.9945 3562141 PK04_181301 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@H](/C=C/C3CC3)[C@@H](O)Cc4ccccc4)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P04 compound treatment 358200.0 -160000.0 -0.43 538430.0 146000.0 0.4 -0.0189 -0.0323 3562143 PK04_181302 COc1cc2CCN(=Cc2cc1OC)Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P05 compound treatment 303200.0 -215000.0 -0.57 311690.0 -81200.0 -0.22 -0.5629 -0.9154 3562144 PK04_181303 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=CCCC=C[C@H]4[C@@H]3[C@@H](O)Cc5ccccc5)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P06 compound treatment 288800.0 -229000.0 -0.61 521300.0 128000.0 0.35 -0.1832 -0.2596 1024512 PK04_181304 COc1cc2CCN=C(C)c2cc1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P07 compound treatment 217070.0 -301000.0 -0.8 203910.0 -189000.0 -0.52 -0.9348 -0.9777 3562146 PK04_181305 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3C51CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P08 compound treatment 222970.0 -295000.0 -0.79 357800.0 -35100.0 -0.1 -0.6249 -0.7878 3562148 PK04_181306 COc1cc2CC(C)N(=Cc2cc1OC)Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P09 compound treatment 209370.0 -308000.0 -0.82 237020.0 -156000.0 -0.43 -0.8851 -0.9535 3562149 PK04_181307 COC(=O)C1(CCCC1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P10 compound treatment 193600.0 -324000.0 -0.87 263280.0 -130000.0 -0.36 -0.8639 -0.9229 1003512 PK04_181308 C[n+]1ccc2ccccc2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P11 mock treatment 257920.0 -260000.0 -0.69 356070.0 -36900.0 -0.1 -0.5623 -0.8017 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P12 mock treatment 225240.0 -293000.0 -0.78 235160.0 -158000.0 -0.43 -0.8587 -0.9613 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P13 compound treatment 174150.0 -344000.0 -0.92 183520.0 -209000.0 -0.57 -1.0555 -0.9746 3562151 PK04_181309 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3C[C@](C)(OC)O[C@@H](Cc4ccccc4)[C@H]3/C=C/C5CC5)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P14 compound treatment 193710.0 -324000.0 -0.87 311640.0 -81300.0 -0.22 -0.7698 -0.8613 1009497 PK04_181310 Cc1cc[n+](C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P15 compound treatment 151840.0 -366000.0 -0.98 200210.0 -193000.0 -0.53 -1.0652 -0.9585 3562153 PK04_181311 COC(=O)[C@@H]1N[C@H](SC1(C)C)[C@@H]2N(CC#C)[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P16 compound treatment 167600.0 -350000.0 -0.94 227640.0 -165000.0 -0.45 -0.9822 -0.9449 1023898 PK04_181312 COc1cc2CC[N+](=Cc2cc1OC)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P17 compound treatment 204390.0 -313000.0 -0.84 173250.0 -220000.0 -0.6 -1.0183 -0.9871 3562155 PK04_181313 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC(=C[C@@H]3[C@@H](O)Cc4ccccc4)/C=C/C5CC5)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P18 compound treatment 198280.0 -319000.0 -0.85 332530.0 -60400.0 -0.17 -0.7206 -0.829 1071838 PK04_181314 COc1cc2CC[N+](=C(C)c2cc1OC)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P19 compound treatment 237700.0 -280000.0 -0.75 267280.0 -126000.0 -0.34 -0.7728 -0.9382 3562157 PK04_181315 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)C41CCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P20 compound treatment 251330.0 -266000.0 -0.71 232340.0 -161000.0 -0.44 -0.8149 -0.9735 1023900 PK04_181316 COc1cc2CC(C)[N+](=Cc2cc1OC)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P21 compound treatment 200250.0 -317000.0 -0.85 251250.0 -142000.0 -0.39 -0.8747 -0.9375 3562159 PK04_181317 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=C[C@@H](C5CC5)n6n(C4[C@@H]3[C@@H](O)Cc7ccccc7)c(=O)n(C)c6=O)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P22 compound treatment 200840.0 -317000.0 -0.85 200180.0 -193000.0 -0.53 -0.9727 -0.9744 1107245 PK04_181318 COc1ccc(C[n+]2ccc3ccccc3c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P23 compound treatment 204590.0 -313000.0 -0.84 214930.0 -178000.0 -0.49 -0.937 -0.9672 3562161 PK04_181319 CC(=CCc1cc(/C=C/2\OC(=O)C(=C2O)c3cc4CCC(C)(C)Oc4cc3O)ccc1O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2181 P24 compound treatment 193700.0 -324000.0 -0.87 211470.0 -181000.0 -0.5 -0.9643 -0.9656 3562163 PK04_181320 COc1ccc(C[n+]2ccc(C)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A01 compound treatment 204480.0 -299000.0 -0.8 152800.0 -367000.0 -1.01 -1.2779 -0.9933 1952677 BCB03_000001 CCCCCCC#Cc1c(C(CC(=O)C)c2ccccc2)c(=O)oc3ccccc13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A02 compound treatment 203210.0 -300000.0 -0.8 241950.0 -278000.0 -0.76 -1.1072 -0.9997 3092787 BCB03_000002 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A03 compound treatment 707370.0 204000.0 0.54 766030.0 246000.0 0.68 0.8624 0.9943 1952679 BCB03_000003 Clc1ccc2oc(=O)cc(Sc3ccccc3)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A04 compound treatment 149160.0 -354000.0 -0.95 253210.0 -267000.0 -0.73 -1.1874 -0.992 3092788 BCB03_000004 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccc2C(F)(F)F)c3ccccc3C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A05 compound treatment 406000.0 -97500.0 -0.26 202000.0 -318000.0 -0.87 -0.8017 -0.8797 1952690 BCB03_000005 COC(=O)CC(C(=O)OC)c1ccccc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A06 compound treatment 166560.0 -337000.0 -0.9 256000.0 -264000.0 -0.73 -1.1491 -0.9943 3001175 BCB03_000006 CON(C)C(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A07 compound treatment 435110.0 -68400.0 -0.18 221280.0 -299000.0 -0.82 -0.7093 -0.844 1952707 BCB03_000007 CCCCSc1cc(=O)oc2cc(OC)ccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A08 compound treatment 270620.0 -233000.0 -0.62 499280.0 -20800.0 -0.06 -0.4803 -0.7688 3001176 BCB03_000008 CC(C)OC(=O)CC(=O)CC(O)c1ccc(cc1)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A09 compound treatment 611890.0 108000.0 0.29 317480.0 -203000.0 -0.56 -0.1887 -0.3009 1952793 BCB03_000009 FC(F)(F)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A10 compound treatment 268380.0 -235000.0 -0.63 186140.0 -334000.0 -0.92 -1.0925 -0.983 3001249 BCB03_000010 CC(C)OC(=O)CC(=O)CC(O)c1cccc(c1)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A11 compound treatment 399720.0 -104000.0 -0.28 354080.0 -166000.0 -0.46 -0.5184 -0.9716 1952795 BCB03_000011 COC(=O)/C=C/c1cc(OC)cc(C#Cc2ccc(Oc3ccccc3)c(OC)c2)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A12 compound treatment 199250.0 -304000.0 -0.81 202200.0 -318000.0 -0.87 -1.1918 -0.9994 3001250 BCB03_000012 CC(C)OC(=O)CC(=O)CC(O)c1cccc(C#N)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A13 mock treatment 602100.0 98600.0 0.26 514130.0 -5960.0 -0.02 0.1746 0.6618 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A14 mock treatment 406840.0 -96700.0 -0.26 698420.0 178000.0 0.49 0.1635 0.2955 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A15 compound treatment 282450.0 -221000.0 -0.59 577540.0 57400.0 0.16 -0.3061 -0.5007 1952801 BCB03_000013 Oc1ccccc1C#Cc2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A16 compound treatment 613650.0 110000.0 0.29 279040.0 -241000.0 -0.66 -0.26 -0.359 3001251 BCB03_000014 CC(C)OC(=O)CC(=O)CC(O)c1ccc(C#N)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A17 compound treatment 376730.0 -127000.0 -0.34 262760.0 -257000.0 -0.71 -0.7391 -0.9433 1952761 BCB03_000015 COc1ccc(cc1)C(=C2C(=O)Oc3ccccc23)c4ccc(OC)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A18 compound treatment 352250.0 -151000.0 -0.4 448480.0 -71600.0 -0.2 -0.4248 -0.9452 3001252 BCB03_000016 COC(=O)C1=CCC(CC1)(C=C)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A19 compound treatment 259810.0 -244000.0 -0.65 510850.0 -9240.0 -0.03 -0.4783 -0.7341 1952804 BCB03_000017 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCCCC2)c1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A20 compound treatment 559100.0 55600.0 0.15 278960.0 -241000.0 -0.66 -0.3632 -0.5353 3001253 BCB03_000018 COC(=O)/C=C(/CC(O)c1cccc(Cl)c1)\OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A21 compound treatment 393120.0 -110000.0 -0.29 539270.0 19200.0 0.05 -0.1713 -0.5718 1952805 BCB03_000019 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(cc2c(coc12)C(O)(c3ccccc3)c4ccccc4)c5cc(I)cc(I)c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A22 compound treatment 238670.0 -265000.0 -0.71 317280.0 -203000.0 -0.56 -0.894 -0.993 3001254 BCB03_000020 OC(C/C(=C/C(=O)OCCF)/OCCF)c1cccc(Cl)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A23 compound treatment 302990.0 -201000.0 -0.54 392180.0 -128000.0 -0.35 -0.6271 -0.979 1952808 BCB03_000021 CCCCCc1cc2ccccc2o1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 A24 compound treatment 314830.0 -189000.0 -0.5 447730.0 -72400.0 -0.2 -0.4969 -0.9171 3001255 BCB03_000022 CCO/C(=C\C(=O)OC)/CC(O)c1cccc(Cl)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B01 compound treatment 832170.0 329000.0 0.88 762900.0 243000.0 0.67 1.092 0.9908 3000770 BCB03_000023 Cc1ccc(cc1)S(=O)(=O)N2C[C@H]([C@@H](C[C@H]2c3ccccc3)Sc4ccccc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B02 compound treatment 319760.0 -184000.0 -0.49 242350.0 -278000.0 -0.76 -0.8863 -0.9773 3070361 BCB03_000024 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B03 compound treatment 769980.0 266000.0 0.71 834090.0 314000.0 0.86 1.1128 0.9955 3000771 BCB03_000025 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B04 compound treatment 285600.0 -218000.0 -0.58 567100.0 47000.0 0.13 -0.3204 -0.5373 3189527 BCB03_000026 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B05 compound treatment 263740.0 -240000.0 -0.64 453870.0 -66200.0 -0.18 -0.5815 -0.8733 3092495 BCB03_000027 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B06 compound treatment 493130.0 -10400.0 -0.03 315410.0 -205000.0 -0.56 -0.417 -0.7412 3189528 BCB03_000028 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B07 compound treatment 378990.0 -125000.0 -0.33 270470.0 -250000.0 -0.69 -0.7198 -0.9449 3092496 BCB03_000029 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B08 compound treatment 817050.0 314000.0 0.84 753930.0 234000.0 0.64 1.0461 0.9914 3189529 BCB03_000030 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3c5ccc(CO)cc5)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B09 compound treatment 332740.0 -171000.0 -0.46 274620.0 -245000.0 -0.67 -0.7991 -0.9819 3000773 BCB03_000031 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B10 compound treatment 237030.0 -267000.0 -0.71 743060.0 223000.0 0.61 -0.0705 -0.0751 3070364 BCB03_000032 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4ccc(CN5CCCC5)cc4)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B11 compound treatment 320000.0 -184000.0 -0.49 389480.0 -131000.0 -0.36 -0.6002 -0.9882 3000774 BCB03_000033 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B12 compound treatment 454780.0 -48800.0 -0.13 337600.0 -182000.0 -0.5 -0.4464 -0.8623 3189532 BCB03_000034 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4cccs4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B13 mock treatment 306510.0 -197000.0 -0.53 687400.0 167000.0 0.46 -0.0473 -0.0678 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B14 mock treatment 774280.0 271000.0 0.72 519520.0 -574.0 0.0 0.5102 0.7056 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B15 compound treatment 562590.0 59000.0 0.16 326950.0 -193000.0 -0.53 -0.2634 -0.4762 3000775 BCB03_000035 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B16 compound treatment 736820.0 233000.0 0.62 410770.0 -109000.0 -0.3 0.2284 0.3302 3189533 BCB03_000036 CC1C=C(CCCO)C/C(=N/P(=O)(Oc2ccccc2)Oc3ccccc3)/N1Cc4cccc(OC(F)(F)F)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B17 compound treatment 225600.0 -278000.0 -0.74 358030.0 -162000.0 -0.44 -0.8396 -0.97 3092507 BCB03_000037 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B18 compound treatment 206850.0 -297000.0 -0.79 168030.0 -352000.0 -0.97 -1.2438 -0.9951 3189534 BCB03_000038 CN1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B19 compound treatment 260530.0 -243000.0 -0.65 450000.0 -70100.0 -0.19 -0.595 -0.8789 3092508 BCB03_000039 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B20 compound treatment 364230.0 -139000.0 -0.37 282790.0 -237000.0 -0.65 -0.7238 -0.9647 3070367 BCB03_000040 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B21 compound treatment 447360.0 -56200.0 -0.15 225410.0 -295000.0 -0.81 -0.6782 -0.8242 3000857 BCB03_000041 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B22 compound treatment 372260.0 -131000.0 -0.35 400420.0 -120000.0 -0.33 -0.4803 -0.9995 3189537 BCB03_000042 CN1C(=O)C2C(C3C(N(C)C2C=C3c4ccc(CO)cc4)c5cccs5)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B23 compound treatment 245520.0 -258000.0 -0.69 621440.0 101000.0 0.28 -0.2906 -0.391 3000858 BCB03_000043 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(Cl)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 B24 compound treatment 510720.0 7180.0 0.02 351890.0 -168000.0 -0.46 -0.313 -0.6772 3189538 BCB03_000044 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C01 compound treatment 704440.0 201000.0 0.54 691420.0 171000.0 0.47 0.712 0.9978 1952809 BCB03_000045 CC(=O)Oc1ccccc1C#Cc2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C02 compound treatment 548750.0 45200.0 0.12 162130.0 -358000.0 -0.98 -0.6095 -0.6156 3092872 BCB03_000046 FCCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C03 compound treatment 698760.0 195000.0 0.52 421650.0 -98400.0 -0.27 0.1776 0.3024 1952811 BCB03_000047 CC(C)(C)[Si](C)(C)Oc1ccc(C#C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C04 compound treatment 244000.0 -260000.0 -0.69 205820.0 -314000.0 -0.86 -1.1003 -0.9941 3000746 BCB03_000048 CC(C)OC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C05 compound treatment 234450.0 -269000.0 -0.72 274780.0 -245000.0 -0.67 -0.9845 -0.9995 1952813 BCB03_000049 OCCCC#Cc1cc(O)cc(Cl)c1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C06 compound treatment 665440.0 162000.0 0.43 352750.0 -167000.0 -0.46 -0.0191 -0.0303 3000748 BCB03_000050 CCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C07 compound treatment 237920.0 -266000.0 -0.71 293450.0 -227000.0 -0.62 -0.9417 -0.9979 1952814 BCB03_000051 CC(=O)Cc1c(Cl)cc(cc1I)C(=O)NCCO[Si](C)(C)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C08 compound treatment 272550.0 -231000.0 -0.62 338830.0 -181000.0 -0.5 -0.7882 -0.9943 3000750 BCB03_000052 COC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C09 compound treatment 659520.0 156000.0 0.42 326720.0 -193000.0 -0.53 -0.0808 -0.1197 1952821 BCB03_000053 CC(C)(C)[Si](C)(C)COCNC(=O)C1CC2C3C(OC2C(Cl)C1)C4(CCCC4)OC3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C10 compound treatment 624260.0 121000.0 0.32 597250.0 77200.0 0.21 0.3778 0.9792 2065163 BCB03_000054 CCOC(=O)/C=C/c1ccccc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C11 mock treatment 320060.0 -183000.0 -0.49 533440.0 13300.0 0.04 -0.3206 -0.6524 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C12 mock treatment 210560.0 -293000.0 -0.78 698890.0 179000.0 0.49 -0.2062 -0.2233 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C13 compound treatment 389080.0 -114000.0 -0.31 462470.0 -57600.0 -0.16 -0.328 -0.953 1952823 BCB03_000055 C#Cc1ccccc1Oc2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C14 compound treatment 504320.0 777.0 0.0 270240.0 -250000.0 -0.69 -0.4836 -0.705 3000752 BCB03_000056 CCOC(=O)/C=C/c1cc(F)ccc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C15 mock treatment 455060.0 -48500.0 -0.13 398680.0 -121000.0 -0.33 -0.3273 -0.9152 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C16 mock treatment 676800.0 173000.0 0.46 235440.0 -285000.0 -0.78 -0.2254 -0.2481 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C17 compound treatment 684320.0 181000.0 0.48 202740.0 -317000.0 -0.87 -0.2747 -0.2757 1952825 BCB03_000057 CCCC(C)(O)C#Cc1cc(cc(C(=O)NCCO[Si](C)(C)C(C)(C)C)c1OC(=O)C)c2cc(F)cc(F)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C18 compound treatment 288340.0 -215000.0 -0.57 597940.0 77800.0 0.21 -0.2553 -0.4163 3000753 BCB03_000058 CCOC(=O)/C=C/c1cc(ccc1O)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C19 compound treatment 41710.0 -462000.0 -1.23 47550.0 -473000.0 -1.3 -1.7896 -0.9997 1952828 BCB03_000059 CCc1cc(OC)c(O)c(C#CC(O)c2ccccc2)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C20 compound treatment 654750.0 151000.0 0.4 232640.0 -287000.0 -0.79 -0.2725 -0.3073 3000754 BCB03_000060 CCOC(=O)/C=C/c1cccc(OC)c1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C21 compound treatment 707270.0 204000.0 0.54 305130.0 -215000.0 -0.59 -0.0325 -0.0405 1952829 BCB03_000061 O=C(/C(=C\c1ccccc1)/c2cccc(c2)S(=O)=O)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C22 compound treatment 543140.0 39600.0 0.11 447260.0 -72800.0 -0.2 -0.0666 -0.2945 3000755 BCB03_000062 CCOC(=O)/C=C/c1cccc(C)c1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C23 compound treatment 314090.0 -189000.0 -0.51 524050.0 3960.0 0.01 -0.3501 -0.6918 1952832 BCB03_000063 CCc1cc(OC)c(O)c(C#CC(C)(O)C=C)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 C24 compound treatment 230520.0 -273000.0 -0.73 335050.0 -185000.0 -0.51 -0.8749 -0.9844 3000762 BCB03_000064 CCOC(=O)/C=C/c1ccccc1OC(=O)C#CC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D01 compound treatment 201400.0 -302000.0 -0.81 444000.0 -76100.0 -0.21 -0.7184 -0.8617 3000859 BCB03_000065 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D02 compound treatment 308410.0 -195000.0 -0.52 458190.0 -61900.0 -0.17 -0.4887 -0.8915 3189665 BCB03_000066 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5ccc(CN6CCCC6)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D03 compound treatment 749170.0 246000.0 0.66 482980.0 -37100.0 -0.1 0.3919 0.5902 3092513 BCB03_000067 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D04 compound treatment 755460.0 252000.0 0.67 300810.0 -219000.0 -0.6 0.0501 0.0555 3189666 BCB03_000068 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D05 compound treatment 669530.0 166000.0 0.44 252960.0 -267000.0 -0.73 -0.2051 -0.2393 3092514 BCB03_000069 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc3ccccc23)S(=O)(=O)c4ccc(C)cc4)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D06 compound treatment 599420.0 95900.0 0.26 220340.0 -300000.0 -0.82 -0.4008 -0.4651 3189668 BCB03_000070 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D07 compound treatment 267460.0 -236000.0 -0.63 364750.0 -155000.0 -0.43 -0.7475 -0.9819 3000861 BCB03_000071 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(F)(F)F)S(=O)(=O)c3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D08 compound treatment 338770.0 -165000.0 -0.44 728720.0 209000.0 0.57 0.0938 0.1299 3189669 BCB03_000072 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D09 compound treatment 692080.0 189000.0 0.5 232700.0 -287000.0 -0.79 -0.2018 -0.2156 3092596 BCB03_000073 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(C)C)S(=O)(=O)c3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D10 compound treatment 605040.0 101000.0 0.27 785220.0 265000.0 0.73 0.7064 0.9094 3189670 BCB03_000074 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D11 mock treatment 401540.0 -102000.0 -0.27 818470.0 298000.0 0.82 0.3866 0.4478 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D12 mock treatment 279120.0 -224000.0 -0.6 572390.0 52300.0 0.14 -0.3223 -0.5229 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D13 compound treatment 308130.0 -195000.0 -0.52 622180.0 102000.0 0.28 -0.1709 -0.2885 3000869 BCB03_000075 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccccc2F)S(=O)(=O)c3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D14 compound treatment 617570.0 114000.0 0.3 245120.0 -275000.0 -0.75 -0.3184 -0.3912 3070434 BCB03_000076 NC(=O)N1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D15 mock treatment 412730.0 -90800.0 -0.24 372340.0 -148000.0 -0.41 -0.4584 -0.9698 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D16 mock treatment 349050.0 -154000.0 -0.41 694370.0 174000.0 0.48 0.0465 0.0737 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D17 compound treatment 334400.0 -169000.0 -0.45 300530.0 -220000.0 -0.6 -0.7457 -0.9899 3000870 BCB03_000077 CCOC(=O)C1=C[C@@H](CC)N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D18 compound treatment 396410.0 -107000.0 -0.29 629600.0 110000.0 0.3 0.0102 0.0247 3189673 BCB03_000078 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D19 compound treatment 274730.0 -229000.0 -0.61 241500.0 -279000.0 -0.76 -0.973 -0.9938 3092599 BCB03_000079 CCOC(=O)C1=CCN(C1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D20 compound treatment 331130.0 -172000.0 -0.46 285400.0 -235000.0 -0.64 -0.7812 -0.9864 3189674 BCB03_000080 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)CC2)c4cccs4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D21 compound treatment 660800.0 157000.0 0.42 484660.0 -35400.0 -0.1 0.2282 0.5293 3092600 BCB03_000081 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)OCC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D22 compound treatment 297340.0 -206000.0 -0.55 247240.0 -273000.0 -0.75 -0.9191 -0.9886 3070436 BCB03_000082 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D23 compound treatment 380960.0 -123000.0 -0.33 372260.0 -148000.0 -0.41 -0.5185 -0.9943 3092601 BCB03_000083 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 D24 compound treatment 554600.0 51100.0 0.14 357140.0 -163000.0 -0.45 -0.2199 -0.4702 3070437 BCB03_000084 CN1CCC(=CC1C2CC2)CCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E01 mock treatment 418880.0 -84700.0 -0.23 825710.0 306000.0 0.84 0.4334 0.4987 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E02 mock treatment 816040.0 312000.0 0.83 798210.0 278000.0 0.76 1.1301 0.999 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E03 mock treatment 794110.0 291000.0 0.78 367150.0 -153000.0 -0.42 0.2519 0.2854 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E04 compound treatment 517530.0 14000.0 0.04 729090.0 209000.0 0.57 0.4321 0.7516 3093836 BCB03_000085 CCOC(=O)[C@H]1CC=C2[C@@H]1c3ccccc3OC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E05 compound treatment 382050.0 -121000.0 -0.32 808330.0 288000.0 0.79 0.3301 0.3859 1952837 BCB03_000086 COCCNC(=O)c1ccc(c(C#CC(C)(O)CC(C)C)c1O)c2cc(F)cc(F)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E06 compound treatment 317080.0 -186000.0 -0.5 801310.0 281000.0 0.77 0.1938 0.2109 3000764 BCB03_000087 CCOC(=O)[C@H]1CC=C2[C@@H]1c3cc(Br)ccc3OC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E07 compound treatment 439420.0 -64100.0 -0.17 751040.0 231000.0 0.63 0.3272 0.4982 1952838 BCB03_000088 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCC3C2CC4Cc5cc(O)ccc5C43)c1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E08 compound treatment 585700.0 82200.0 0.22 246880.0 -273000.0 -0.75 -0.3752 -0.4801 3000765 BCB03_000089 CCOC(=O)/C=C/c1cc(Br)ccc1OC(=O)C#CC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E09 mock treatment 339520.0 -164000.0 -0.44 604280.0 84200.0 0.23 -0.1464 -0.2955 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E10 mock treatment 553600.0 50100.0 0.13 492160.0 -27900.0 -0.08 0.0403 0.2615 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E11 compound treatment 281680.0 -222000.0 -0.59 573600.0 53500.0 0.15 -0.3152 -0.5162 1952839 BCB03_000090 Oc1ccccc1C#CC#Cc2ccccc2O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E12 compound treatment 182680.0 -321000.0 -0.86 402970.0 -117000.0 -0.32 -0.8334 -0.9104 3000766 BCB03_000091 O=c1oc2ccccc2cc1C#C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E13 compound treatment 267840.0 -236000.0 -0.63 686440.0 166000.0 0.46 -0.1222 -0.1572 1952842 BCB03_000092 COC(=O)Cc1cc(cc(I)c1O)c2cc(F)cc(I)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E14 compound treatment 345090.0 -158000.0 -0.42 694470.0 174000.0 0.48 0.0393 0.0614 3000767 BCB03_000093 Cn1c2C3NC(C(=O)c2c4ccccc14)C(C)(C=C3)C(=O)OCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E15 compound treatment 179630.0 -324000.0 -0.87 313140.0 -207000.0 -0.57 -1.0135 -0.9792 2065685 BCB03_000094 CCOCOc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OCOCC)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E16 compound treatment 454330.0 -49200.0 -0.13 434960.0 -85100.0 -0.23 -0.2582 -0.9629 3000768 BCB03_000095 [O-][N+](=O)c1ccccc1S(=O)(=O)N2C3CC=C(C2C(=O)c4c3[nH]c5ccccc45)C(=O)OCc6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E17 mock treatment 720380.0 217000.0 0.58 718820.0 199000.0 0.55 0.7953 0.9996 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E18 mock treatment 574360.0 70800.0 0.19 294080.0 -226000.0 -0.62 -0.305 -0.4702 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E19 compound treatment 395100.0 -108000.0 -0.29 271760.0 -248000.0 -0.68 -0.6869 -0.9273 2065729 BCB03_000096 CCOCOc1cc(OCOCC)c2C(=O)CC(Oc2c1)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E20 compound treatment 281880.0 -222000.0 -0.59 443040.0 -77100.0 -0.21 -0.5682 -0.9038 3093843 BCB03_000097 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E21 compound treatment 733200.0 230000.0 0.61 413290.0 -107000.0 -0.29 0.2264 0.333 1952773 BCB03_000098 CCCNC(=O)c1cc(cc2c3C(=O)OC4(CCCC4)c3oc12)c5cc(F)cc(F)c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E22 compound treatment 211360.0 -292000.0 -0.78 506400.0 -13700.0 -0.04 -0.5784 -0.7403 3000776 BCB03_000099 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(CC)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E23 compound treatment 261400.0 -242000.0 -0.65 303900.0 -216000.0 -0.59 -0.877 -0.9991 1952780 BCB03_000100 COc1cccc(c1)c2c(oc3ccccc23)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 E24 compound treatment 604390.0 101000.0 0.27 442890.0 -77200.0 -0.21 0.0406 0.1184 3000848 BCB03_000101 CCOC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(CC)C2=O)Sc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F01 mock treatment 490880.0 -12700.0 -0.03 314960.0 -205000.0 -0.56 -0.4221 -0.7482 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F02 mock treatment 497360.0 -6180.0 -0.02 649250.0 129000.0 0.35 0.2391 0.6734 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F03 compound treatment 363200.0 -140000.0 -0.37 514900.0 -5190.0 -0.01 -0.2751 -0.7335 3000874 BCB03_000102 Cc1ccc(cc1)[C@@H]2N(CC=C2C(=O)O)S(=O)(=O)c3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F04 compound treatment 742920.0 239000.0 0.64 290030.0 -230000.0 -0.63 0.0055 0.0061 3187712 BCB03_000103 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4ccc(CN5CCCC5)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F05 compound treatment 310560.0 -193000.0 -0.52 332850.0 -187000.0 -0.51 -0.728 -1.0 3092602 BCB03_000104 C[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F06 compound treatment 522460.0 18900.0 0.05 211240.0 -309000.0 -0.85 -0.5639 -0.6638 3187713 BCB03_000105 CN1C(C2CC2)C3C4C(C1C=C3c5ccc(CO)cc5)C(=O)N(C(=O)N)C4=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F07 compound treatment 467680.0 -35900.0 -0.1 551280.0 31200.0 0.09 -0.0072 -0.056 3092680 BCB03_000106 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F08 compound treatment 670990.0 167000.0 0.45 328970.0 -191000.0 -0.52 -0.0548 -0.0794 3187714 BCB03_000107 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)CC1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F09 mock treatment 272330.0 -231000.0 -0.62 303810.0 -216000.0 -0.59 -0.8566 -0.9998 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F10 mock treatment 707580.0 204000.0 0.54 509300.0 -10800.0 -0.03 0.3644 0.6677 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F11 compound treatment 568840.0 65300.0 0.17 177150.0 -343000.0 -0.94 -0.5424 -0.5665 3092681 BCB03_000108 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F12 compound treatment 277340.0 -226000.0 -0.6 636970.0 117000.0 0.32 -0.2003 -0.2928 3070498 BCB03_000109 CC1C=C(CCCO)CCN1Cc2cccc(OC(F)(F)F)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F13 compound treatment 775200.0 272000.0 0.73 237000.0 -283000.0 -0.78 -0.0365 -0.0343 3000959 BCB03_000110 CC(C)[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F14 compound treatment 191810.0 -312000.0 -0.83 243640.0 -276000.0 -0.76 -1.1254 -0.9989 3070499 BCB03_000111 CN1CCC(=CC1c2cccs2)c3ccc(CO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F15 compound treatment 330910.0 -173000.0 -0.46 683840.0 164000.0 0.45 -0.0082 -0.0127 3092683 BCB03_000112 Cc1ccc(cc1)[C@@H]2N([C@@H](C=C2C(=O)O)C(C)(C)C)S(=O)(=O)c3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F16 compound treatment 704020.0 200000.0 0.54 370340.0 -150000.0 -0.41 0.0879 0.1302 3187718 BCB03_000113 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4cccs4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F17 mock treatment 266370.0 -237000.0 -0.63 343680.0 -176000.0 -0.48 -0.7904 -0.9912 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F18 mock treatment 294400.0 -209000.0 -0.56 334880.0 -185000.0 -0.51 -0.7546 -0.9989 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F19 compound treatment 715360.0 212000.0 0.57 669120.0 149000.0 0.41 0.6894 0.9873 3092684 BCB03_000114 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F20 compound treatment 273820.0 -230000.0 -0.61 327780.0 -192000.0 -0.53 -0.8072 -0.9972 3187719 BCB03_000115 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)CC1)c4ccc(CN5CCCC5)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F21 compound treatment 271890.0 -232000.0 -0.62 256690.0 -263000.0 -0.72 -0.9489 -0.997 3000962 BCB03_000116 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F22 compound treatment 390590.0 -113000.0 -0.3 203850.0 -316000.0 -0.87 -0.8273 -0.9 3187720 BCB03_000117 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)CC2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F23 compound treatment 225830.0 -278000.0 -0.74 257600.0 -262000.0 -0.72 -1.0341 -0.9999 3092686 BCB03_000118 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 F24 compound treatment 479890.0 -23700.0 -0.06 562840.0 42700.0 0.12 0.0383 0.2874 3070502 BCB03_000119 CN1C(C2C3C(C1C=C2c4ccc(CO)cc4)C(=O)N(C(=O)N)C3=O)c5cccs5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G01 compound treatment 395750.0 -108000.0 -0.29 539700.0 19600.0 0.05 -0.1655 -0.5651 3107406 BCB03_000120 COC(=O)/C=C/c1cc(OC)c2oc(c(C)c2c1)c3ccccc3.c1ccsc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G02 compound treatment 653200.0 150000.0 0.4 548870.0 28800.0 0.08 0.3385 0.8308 3000850 BCB03_000121 OC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G03 mock treatment 478720.0 -24800.0 -0.07 432260.0 -87800.0 -0.24 -0.2174 -0.8693 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G04 mock treatment 748290.0 245000.0 0.65 255100.0 -265000.0 -0.73 -0.0522 -0.0534 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G05 compound treatment 308800.0 -195000.0 -0.52 681120.0 161000.0 0.44 -0.0552 -0.0809 1952785 BCB03_000122 CCc1cc(OC)c2oc(c(C(=O)c3ccccc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G06 compound treatment 874440.0 371000.0 0.99 359970.0 -160000.0 -0.44 0.3897 0.3595 3092501 BCB03_000123 OC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3)Sc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G07 compound treatment 596510.0 93000.0 0.25 730980.0 211000.0 0.58 0.585 0.9286 1952788 BCB03_000124 CCc1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G08 compound treatment 730280.0 227000.0 0.61 762410.0 242000.0 0.67 0.8986 0.9989 3092502 BCB03_000125 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G09 compound treatment 626320.0 123000.0 0.33 215300.0 -305000.0 -0.84 -0.3598 -0.4003 2065776 BCB03_000126 Cc1ccc(SC2(CC(=O)N(Cc3ccccc3)C2c4ccccc4I)C(=O)NCc5ccccc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G10 compound treatment 628100.0 125000.0 0.33 345760.0 -174000.0 -0.48 -0.1032 -0.177 3000853 BCB03_000127 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G11 compound treatment 775330.0 272000.0 0.73 283560.0 -237000.0 -0.65 0.0541 0.0556 1034979 BCB03_000128 c1c(cn2ccccc12)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G12 compound treatment 155680.0 -348000.0 -0.93 154650.0 -365000.0 -1.0 -1.3664 -0.9993 3000854 BCB03_000129 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G13 compound treatment 160980.0 -343000.0 -0.91 194490.0 -326000.0 -0.89 -1.2791 -0.9999 2065809 BCB03_000130 COC(=O)Cc1cn[nH]c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G14 compound treatment 257240.0 -246000.0 -0.66 183470.0 -337000.0 -0.92 -1.1187 -0.9861 3000855 BCB03_000131 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G15 compound treatment 471260.0 -32300.0 -0.09 379000.0 -141000.0 -0.39 -0.3349 -0.8439 2065826 BCB03_000132 CC(C(=O)O)c1ccccc1C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G16 compound treatment 253920.0 -250000.0 -0.67 192700.0 -327000.0 -0.9 -1.107 -0.9892 3000862 BCB03_000133 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2C)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G17 compound treatment 296200.0 -207000.0 -0.55 286030.0 -234000.0 -0.64 -0.846 -0.9973 2065840 BCB03_000134 CCOC(=O)CC(CC(=O)OCC)(C(=O)OCC)c1cccnc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G18 compound treatment 380530.0 -123000.0 -0.33 441720.0 -78400.0 -0.22 -0.3845 -0.9789 3000863 BCB03_000135 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)C[Si](C)(C)C)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G19 mock treatment 604260.0 101000.0 0.27 526670.0 6580.0 0.02 0.203 0.7529 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G20 mock treatment 362110.0 -141000.0 -0.38 623490.0 103000.0 0.28 -0.0664 -0.1405 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G21 compound treatment 441290.0 -62300.0 -0.17 234240.0 -286000.0 -0.78 -0.6725 -0.8383 2065855 BCB03_000136 CCOC(=O)CC(C(=O)OCC)c1cccnc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G22 compound treatment 511890.0 8350.0 0.02 256160.0 -264000.0 -0.72 -0.4966 -0.685 3092589 BCB03_000137 CCOC(=O)C1=CC[C@H](N([C@H]1/C=C/c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G23 compound treatment 30560.0 -473000.0 -1.26 39940.0 -480000.0 -1.32 -1.8254 -0.9998 2065872 BCB03_000138 CCOC(=O)/C(=C/1\NSc2ccccc12)/C#N 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 G24 compound treatment 625600.0 122000.0 0.33 386510.0 -134000.0 -0.37 -0.0288 -0.0587 3092590 BCB03_000139 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4cccc(Cl)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H01 compound treatment 634900.0 131000.0 0.35 600770.0 80700.0 0.22 0.4047 0.9754 3092687 BCB03_000140 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H02 compound treatment 385300.0 -118000.0 -0.32 319680.0 -200000.0 -0.55 -0.6124 -0.9653 3187850 BCB03_000141 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)CC1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H03 mock treatment 333930.0 -170000.0 -0.45 793920.0 274000.0 0.75 0.2112 0.2407 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H04 mock treatment 770880.0 267000.0 0.71 225120.0 -295000.0 -0.81 -0.0677 -0.0627 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H05 compound treatment 253340.0 -250000.0 -0.67 306200.0 -214000.0 -0.59 -0.8878 -0.9979 3092697 BCB03_000142 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H06 compound treatment 624350.0 121000.0 0.32 694780.0 175000.0 0.48 0.5673 0.9814 3187852 BCB03_000143 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4ccc(CN5CCCC5)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H07 compound treatment 194160.0 -309000.0 -0.83 421240.0 -98900.0 -0.27 -0.7762 -0.8924 3092698 BCB03_000144 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccco3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H08 compound treatment 483610.0 -19900.0 -0.05 359480.0 -161000.0 -0.44 -0.3494 -0.7868 3187853 BCB03_000145 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C(=O)N)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H09 compound treatment 712650.0 209000.0 0.56 168830.0 -351000.0 -0.96 -0.287 -0.2575 3092699 BCB03_000146 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H10 compound treatment 692530.0 189000.0 0.5 739690.0 220000.0 0.6 0.7832 0.9961 3070552 BCB03_000147 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)CC1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H11 compound treatment 450510.0 -53000.0 -0.14 348160.0 -172000.0 -0.47 -0.4339 -0.8805 3092700 BCB03_000148 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(Br)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H12 compound treatment 225060.0 -278000.0 -0.74 227640.0 -292000.0 -0.8 -1.0937 -0.9993 3070553 BCB03_000149 CN1CCC(=CC1c2cccs2)CCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H13 compound treatment 553120.0 49600.0 0.13 339840.0 -180000.0 -0.49 -0.2563 -0.5003 3000975 BCB03_000150 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)C(C)C)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H14 compound treatment 293480.0 -210000.0 -0.56 617360.0 97300.0 0.27 -0.2079 -0.3346 3187856 BCB03_000151 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H15 compound treatment 207200.0 -296000.0 -0.79 426160.0 -93900.0 -0.26 -0.742 -0.8914 3000976 BCB03_000152 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](C=C([C@@H]2c3ccccc3)C(=O)O)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H16 compound treatment 159220.0 -344000.0 -0.92 768390.0 248000.0 0.68 -0.1683 -0.147 3187857 BCB03_000153 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H17 compound treatment 824970.0 321000.0 0.86 199370.0 -321000.0 -0.88 -0.0156 -0.0126 3092773 BCB03_000154 CC(C)[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H18 compound treatment 404540.0 -99000.0 -0.26 271620.0 -248000.0 -0.68 -0.6693 -0.9149 3070555 BCB03_000155 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)CC2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H19 mock treatment 321410.0 -182000.0 -0.49 309840.0 -210000.0 -0.58 -0.7522 -0.9964 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H20 mock treatment 224730.0 -279000.0 -0.74 255620.0 -264000.0 -0.73 -1.04 -0.9999 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H21 compound treatment 776810.0 273000.0 0.73 503370.0 -16700.0 -0.05 0.4836 0.6613 3092774 BCB03_000156 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H22 compound treatment 464710.0 -38800.0 -0.1 271690.0 -248000.0 -0.68 -0.5556 -0.8054 3070556 BCB03_000157 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H23 compound treatment 372340.0 -131000.0 -0.35 474290.0 -45800.0 -0.13 -0.3367 -0.9044 3092783 BCB03_000158 CCC[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 H24 compound treatment 271200.0 -232000.0 -0.62 309660.0 -210000.0 -0.58 -0.8473 -0.9994 3070597 BCB03_000159 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I01 compound treatment 294590.0 -209000.0 -0.56 841080.0 321000.0 0.88 0.2285 0.219 2065633 BCB03_000160 CCOC(=O)CC(C#N)(C(=O)OCC)c1nsc2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I02 compound treatment 727390.0 224000.0 0.6 522950.0 2860.0 0.01 0.4283 0.7163 3000865 BCB03_000161 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2I)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I03 compound treatment 276660.0 -227000.0 -0.61 557720.0 37600.0 0.1 -0.3555 -0.5782 2065650 BCB03_000162 [O-][N+](=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(I)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I04 compound treatment 181720.0 -322000.0 -0.86 338430.0 -182000.0 -0.5 -0.9605 -0.9665 3000866 BCB03_000163 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I05 mock treatment 595900.0 92400.0 0.25 515310.0 -4780.0 -0.01 0.1651 0.6685 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I06 mock treatment 475840.0 -27700.0 -0.07 791520.0 271000.0 0.75 0.4746 0.6338 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I07 compound treatment 351810.0 -152000.0 -0.41 279880.0 -240000.0 -0.66 -0.7529 -0.9727 1065064 BCB03_000164 [O-][N+](=O)c1ccc(CBr)c(I)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I08 compound treatment 277630.0 -226000.0 -0.6 365120.0 -155000.0 -0.43 -0.7275 -0.9854 3000867 BCB03_000165 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I09 compound treatment 312390.0 -191000.0 -0.51 454080.0 -66000.0 -0.18 -0.4892 -0.9029 2065874 BCB03_000166 COC(=O)C(C(=O)OC)c1ccc(cc1I)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I10 compound treatment 891090.0 388000.0 1.04 567360.0 47300.0 0.13 0.8237 0.7896 3092595 BCB03_000167 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(SC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCc5ccccc5)c(OC)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I11 compound treatment 710560.0 207000.0 0.55 766880.0 247000.0 0.68 0.8701 0.9949 BCB03_000168 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I12 compound treatment 304810.0 -199000.0 -0.53 261870.0 -258000.0 -0.71 -0.8766 -0.9898 3000949 BCB03_000169 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4cccc(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I13 compound treatment 5640.0 -498000.0 -1.33 4120.0 -516000.0 -1.42 -1.942 -0.9995 3107360 BCB03_000170 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I14 compound treatment 608440.0 105000.0 0.28 609870.0 89800.0 0.25 0.3724 0.998 3000951 BCB03_000171 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I15 compound treatment 573000.0 69500.0 0.19 576400.0 56300.0 0.15 0.2405 0.9959 1952728 BCB03_000172 Cc1ccc2oc(=O)cc(c3cccs3)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I16 compound treatment 347920.0 -156000.0 -0.42 245230.0 -275000.0 -0.75 -0.8275 -0.9605 3000952 BCB03_000173 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I17 compound treatment 485440.0 -18100.0 -0.05 764960.0 245000.0 0.67 0.4412 0.6546 1952730 BCB03_000174 O=c1cc(Cc2ccccc2)c3ccccc3o1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I18 compound treatment 447520.0 -56000.0 -0.15 480740.0 -39400.0 -0.11 -0.1822 -0.9872 3092606 BCB03_000175 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(F)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I19 compound treatment 172250.0 -331000.0 -0.88 124240.0 -396000.0 -1.09 -1.3942 -0.9948 1952746 BCB03_000176 Cc1ccc(cc1)c2cc(=O)oc3ccccc23 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I20 compound treatment 329000.0 -175000.0 -0.47 321850.0 -198000.0 -0.54 -0.7145 -0.997 3092607 BCB03_000177 CCOC(=O)[C@@H]1N([C@@H](CC=C1C(=O)OCC)c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I21 mock treatment 290960.0 -213000.0 -0.57 360100.0 -160000.0 -0.44 -0.7121 -0.992 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I22 mock treatment 412000.0 -91500.0 -0.24 594240.0 74100.0 0.2 -0.029 -0.091 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I23 compound treatment 317950.0 -186000.0 -0.5 345070.0 -175000.0 -0.48 -0.6903 -0.9999 3005760 BCB03_000178 CCOP(=O)(O)OCC.Cc1cc(=O)oc2ccc(Cl)cc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 I24 compound treatment 585000.0 81500.0 0.22 455890.0 -64200.0 -0.18 0.0292 0.1043 3000954 BCB03_000179 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J01 compound treatment 786400.0 283000.0 0.76 657700.0 138000.0 0.38 0.8014 0.9487 3092784 BCB03_000180 CCS[C@@H]1[C@@H](CC)N([C@H]([C@@H]1C(=O)O)c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J02 compound treatment 626180.0 123000.0 0.33 521130.0 1040.0 0.0 0.2336 0.7132 3187985 BCB03_000181 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J03 compound treatment 263770.0 -240000.0 -0.64 752080.0 232000.0 0.64 -0.0025 -0.0028 3092785 BCB03_000182 CCOC1=C2C(N(CC2C3C(C1)C(=O)N(C3=O)c4ccccc4)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J04 compound treatment 759860.0 256000.0 0.68 271310.0 -249000.0 -0.68 0.0011 0.0012 3187986 BCB03_000183 CN1CCC(=CC1c2ccc(CN3CCCC3)cc2)CCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J05 mock treatment 464160.0 -39400.0 -0.11 221920.0 -298000.0 -0.82 -0.6532 -0.7915 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J06 mock treatment 607200.0 104000.0 0.28 510560.0 -9530.0 -0.03 0.1773 0.6374 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J07 compound treatment 827280.0 324000.0 0.86 353130.0 -167000.0 -0.46 0.2873 0.2936 3001173 BCB03_000184 CCOC1=C2C(N(CC2n3n(C1)c(=O)n(c4ccccc4)c3=O)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J08 compound treatment 358590.0 -145000.0 -0.39 437980.0 -82100.0 -0.23 -0.4332 -0.9669 3070607 BCB03_000185 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3ccc(CN4CCCC4)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J09 compound treatment 567770.0 64200.0 0.17 497450.0 -22600.0 -0.06 0.0773 0.4239 3001174 BCB03_000186 Cc1ccc(cc1)C2C3C(CN2S(=O)(=O)c4ccc(C)cc4)C5C(CC3=O)C(=O)N(C5=O)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J10 compound treatment 216850.0 -287000.0 -0.77 589380.0 69300.0 0.19 -0.407 -0.5158 3070608 BCB03_000187 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4cccs4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J11 compound treatment 880380.0 377000.0 1.01 426210.0 -93900.0 -0.26 0.5295 0.5096 3092789 BCB03_000188 CCN1C(=O)C2CC(=O)C3C(N(CC3C2C1=O)S(=O)(=O)c4ccc(C)cc4)c5ccc(C)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J12 compound treatment 811470.0 308000.0 0.82 210160.0 -310000.0 -0.85 -0.0201 -0.017 3070609 BCB03_000189 CN1CCC(=CC1C2CC2)c3ccc(CO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J13 compound treatment 786970.0 283000.0 0.76 253620.0 -266000.0 -0.73 0.018 0.0171 3092790 BCB03_000190 CC[C@@H]1[C@@H]2[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J14 compound treatment 462100.0 -41400.0 -0.11 461800.0 -58300.0 -0.16 -0.1914 -0.9838 3187991 BCB03_000191 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J15 compound treatment 600420.0 96900.0 0.26 487590.0 -32500.0 -0.09 0.1199 0.4379 3092866 BCB03_000192 CC[C@@H]1[C@H]2[C@@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J16 compound treatment 239900.0 -264000.0 -0.7 392090.0 -128000.0 -0.35 -0.7464 -0.9484 3187992 BCB03_000193 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J17 compound treatment 665150.0 162000.0 0.43 411200.0 -109000.0 -0.3 0.0938 0.1787 3092867 BCB03_000194 CCOC(=O)C1=CC[C@H](N([C@H]1CC)S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J18 compound treatment 400960.0 -103000.0 -0.27 687410.0 167000.0 0.46 0.1311 0.245 3187993 BCB03_000195 CN1C(C2CC2)C3C4C(C1C=C3CCCO)C(=O)N(C(=O)N)C4=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J19 compound treatment 532580.0 29000.0 0.08 480640.0 -39500.0 -0.11 -0.0218 -0.1633 3092868 BCB03_000196 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J20 compound treatment 334400.0 -169000.0 -0.45 268990.0 -251000.0 -0.69 -0.8069 -0.979 3187994 BCB03_000197 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C3CC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J21 mock treatment 364410.0 -139000.0 -0.37 391930.0 -128000.0 -0.35 -0.5116 -0.9996 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J22 mock treatment 730670.0 227000.0 0.61 371550.0 -149000.0 -0.41 0.1406 0.1923 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J23 compound treatment 345970.0 -158000.0 -0.42 390190.0 -130000.0 -0.36 -0.5498 -0.9966 3092869 BCB03_000198 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 J24 compound treatment 307000.0 -197000.0 -0.52 649070.0 129000.0 0.35 -0.1208 -0.1908 3070656 BCB03_000199 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)CCCO)C(=O)OCCS(=O)(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K01 compound treatment 663470.0 160000.0 0.43 524000.0 3910.0 0.01 0.3096 0.7246 3005761 BCB03_000200 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K02 compound treatment 657410.0 154000.0 0.41 790650.0 271000.0 0.74 0.8158 0.961 3000955 BCB03_000201 CCOC(=O)C1=CC[C@H](N([C@H]1C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K03 compound treatment 634420.0 131000.0 0.35 581360.0 61300.0 0.17 0.3661 0.9438 1952748 BCB03_000202 O=Cc1cccc(c1)c2cc(=O)oc3ccccc23 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K04 compound treatment 702090.0 199000.0 0.53 558570.0 38500.0 0.11 0.4497 0.8316 3092688 BCB03_000203 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccncc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K05 compound treatment 202690.0 -301000.0 -0.8 98830.0 -421000.0 -1.16 -1.386 -0.9842 1107217 BCB03_000204 Cc1cccnc1I 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K06 compound treatment 486520.0 -17000.0 -0.05 614250.0 94200.0 0.26 0.1506 0.5739 3000965 BCB03_000205 CCOC(=O)C1=CC[C@H](N([C@H]1C=C(C)C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K07 mock treatment 459520.0 -44000.0 -0.12 704480.0 184000.0 0.51 0.2748 0.5288 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K08 mock treatment 556760.0 53200.0 0.14 532660.0 12600.0 0.03 0.1249 0.8539 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K09 compound treatment 760210.0 257000.0 0.69 731420.0 211000.0 0.58 0.895 0.9966 3005761 BCB03_000206 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K10 compound treatment 472180.0 -31400.0 -0.08 752800.0 233000.0 0.64 0.3925 0.6092 3000966 BCB03_000207 CCOC(=O)C1=CC[C@H](N([C@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K11 compound treatment 702340.0 199000.0 0.53 822040.0 302000.0 0.83 0.9616 0.9768 1952755 BCB03_000208 C=C(c1ccccc1)c2cc(=O)oc3ccccc23 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K12 compound treatment 757440.0 254000.0 0.68 467940.0 -52200.0 -0.14 0.3783 0.5458 3092692 BCB03_000209 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K13 compound treatment 275970.0 -228000.0 -0.61 227680.0 -292000.0 -0.8 -0.9975 -0.9906 1952760 BCB03_000210 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(c2cc(F)cc(F)c2)c3oc4c(C(=O)OC4(c5ccccc5)c6ccccc6)c3c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K14 compound treatment 638720.0 135000.0 0.36 257550.0 -263000.0 -0.72 -0.2544 -0.3155 3092693 BCB03_000211 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K15 mock treatment 299320.0 -204000.0 -0.55 724540.0 204000.0 0.56 0.0112 0.0143 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K16 mock treatment 395400.0 -108000.0 -0.29 701470.0 181000.0 0.5 0.1479 0.2569 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K17 compound treatment 709840.0 206000.0 0.55 495650.0 -24400.0 -0.07 0.3422 0.6164 1952770 BCB03_000212 O=C/1Oc2ccccc2C\C1=C(/c3ccccc3)\c4ccc5ccccc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K18 compound treatment 285470.0 -218000.0 -0.58 200000.0 -320000.0 -0.88 -1.0333 -0.9801 3000969 BCB03_000213 CCOC(=O)C1=CC[C@H](N([C@H]1C=C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K19 compound treatment 547100.0 43600.0 0.12 354080.0 -166000.0 -0.46 -0.24 -0.5103 3000871 BCB03_000214 O=c1cccc(o1)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K20 compound treatment 335370.0 -168000.0 -0.45 580720.0 60600.0 0.17 -0.1999 -0.4174 3001047 BCB03_000215 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(c(OC)c4)c5ccc(OCc6ccccc6)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K21 compound treatment 558020.0 54500.0 0.15 534270.0 14200.0 0.04 0.1304 0.8658 3000872 BCB03_000216 COc1cccc(c1)c2cccc(=O)o2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K22 compound treatment 636020.0 132000.0 0.35 510080.0 -10000.0 -0.03 0.2308 0.6502 3001048 BCB03_000217 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K23 mock treatment 294400.0 -209000.0 -0.56 319040.0 -201000.0 -0.55 -0.7853 -1.0 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 K24 mock treatment 640690.0 137000.0 0.37 718930.0 199000.0 0.55 0.645 0.9812 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L01 compound treatment 270240.0 -233000.0 -0.62 421300.0 -98800.0 -0.27 -0.6324 -0.9306 3092870 BCB03_000218 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L02 compound treatment 446170.0 -57400.0 -0.15 679210.0 159000.0 0.44 0.2005 0.4332 3188115 BCB03_000219 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4cccs4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L03 compound treatment 843160.0 340000.0 0.91 534800.0 14700.0 0.04 0.67 0.7378 3092871 BCB03_000220 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(Br)c2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCC=C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L04 compound treatment 675680.0 172000.0 0.46 392760.0 -127000.0 -0.35 0.0779 0.1349 3188116 BCB03_000221 CC1C=C(CCCO)C=C(C(=O)OCCS(=O)(=O)C)C(=CN1Cc2cccc(OC(F)(F)F)c2)C(=O)OCCS(=O)(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L05 compound treatment 574590.0 71000.0 0.19 769600.0 250000.0 0.69 0.6186 0.8702 3092774 BCB03_000222 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L06 compound treatment 230530.0 -273000.0 -0.73 636700.0 117000.0 0.32 -0.2893 -0.3632 3188117 BCB03_000223 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L07 mock treatment 741920.0 238000.0 0.64 247960.0 -272000.0 -0.75 -0.0781 -0.0795 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L08 mock treatment 513340.0 9800.0 0.03 691710.0 172000.0 0.47 0.3517 0.7452 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L09 compound treatment 463390.0 -40200.0 -0.11 478170.0 -41900.0 -0.12 -0.1572 -0.9994 3187870 BCB03_000224 COC(=O)C[C@H]1O[C@@H](CCc2ccccc2)[C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L10 compound treatment 422330.0 -81200.0 -0.22 258800.0 -261000.0 -0.72 -0.6606 -0.8815 3188119 BCB03_000225 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L11 compound treatment 661760.0 158000.0 0.42 920260.0 400000.0 1.1 1.0757 0.9138 3071511 BCB03_000226 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(I)cc52 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L12 compound treatment 497340.0 -6200.0 -0.02 481780.0 -38300.0 -0.11 -0.0861 -0.8085 3188120 BCB03_000227 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3cccs3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L13 compound treatment 635420.0 132000.0 0.35 423690.0 -96400.0 -0.26 0.0619 0.1405 3187872 BCB03_000228 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc52 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L14 compound treatment 615380.0 112000.0 0.3 339480.0 -181000.0 -0.5 -0.1394 -0.2408 3188122 BCB03_000229 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CO)cc3)c4cccs4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L15 mock treatment 525920.0 22400.0 0.06 354270.0 -166000.0 -0.46 -0.2797 -0.609 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L16 mock treatment 511850.0 8310.0 0.02 400070.0 -120000.0 -0.33 -0.2173 -0.658 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L17 compound treatment 798080.0 295000.0 0.79 452390.0 -67700.0 -0.19 0.4249 0.5256 3414061 BCB03_000230 COC(=O)C[C@@H]1C[C@H](C)[C@]2(O1)C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L18 compound treatment 369120.0 -134000.0 -0.36 448290.0 -71800.0 -0.2 -0.3933 -0.9601 3188123 BCB03_000231 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L19 compound treatment 508430.0 4890.0 0.01 720910.0 201000.0 0.55 0.3991 0.7236 3071513 BCB03_000232 CC(C)[Si](OCC[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)O)C(=O)N(Cc3ccccc3)c4ccccc42)(C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L20 compound treatment 164960.0 -339000.0 -0.9 220220.0 -300000.0 -0.82 -1.2216 -0.9989 3188124 BCB03_000233 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L21 compound treatment 504160.0 617.0 0.0 438050.0 -82000.0 -0.23 -0.1581 -0.7019 3071514 BCB03_000234 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccccc53 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L22 compound treatment 410920.0 -92600.0 -0.25 487430.0 -32700.0 -0.09 -0.2383 -0.9058 3188125 BCB03_000235 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L23 mock treatment 522150.0 18600.0 0.05 697070.0 177000.0 0.49 0.3787 0.7754 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 L24 mock treatment 453730.0 -49800.0 -0.13 743440.0 223000.0 0.61 0.3395 0.5411 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M01 compound treatment 675550.0 172000.0 0.46 822680.0 303000.0 0.83 0.9123 0.961 1984103 BCB03_000236 Cc1ccc(cc1)c2cccc(=O)o2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M02 compound treatment 556450.0 52900.0 0.14 586910.0 66800.0 0.18 0.2296 0.9917 3001049 BCB03_000237 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M03 compound treatment 622880.0 119000.0 0.32 569930.0 49800.0 0.14 0.3221 0.9287 3000873 BCB03_000238 Clc1cccc(c1)c2cccc(=O)o2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M04 compound treatment 832170.0 329000.0 0.88 856770.0 337000.0 0.92 1.2743 0.9997 3092778 BCB03_000239 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(CC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M05 compound treatment 658460.0 155000.0 0.41 731320.0 211000.0 0.58 0.7026 0.9863 3000875 BCB03_000240 Clc1ccccc1c2cccc(=O)o2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M06 compound treatment 493780.0 -9760.0 -0.03 751000.0 231000.0 0.63 0.4298 0.6774 3001168 BCB03_000241 CCOC(=O)C1=C(N([C@@H](CC1)c2ccccc2)S(=O)(=O)CC[Si](C)(C)C)C(=O)OCC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M07 compound treatment 416320.0 -87200.0 -0.23 640770.0 121000.0 0.33 0.0695 0.1717 3000956 BCB03_000242 CCCc1cccc(=O)o1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M08 compound treatment 832560.0 329000.0 0.88 420160.0 -99900.0 -0.27 0.4274 0.4643 3092780 BCB03_000243 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4cc(Cl)ccc4Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M09 mock treatment 692320.0 189000.0 0.5 453760.0 -66300.0 -0.18 0.2278 0.4249 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M10 mock treatment 881830.0 378000.0 1.01 701990.0 182000.0 0.5 1.0676 0.9472 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M11 compound treatment 882950.0 379000.0 1.01 643160.0 123000.0 0.34 0.9555 0.8945 3000957 BCB03_000244 Fc1ccc(cc1)c2cccc(=O)o2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M12 compound treatment 849360.0 346000.0 0.92 292920.0 -227000.0 -0.62 0.2121 0.1903 3092781 BCB03_000245 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M13 mock treatment 521710.0 18200.0 0.05 358940.0 -161000.0 -0.44 -0.2785 -0.6258 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M14 mock treatment 584380.0 80800.0 0.22 511480.0 -8610.0 -0.02 0.136 0.6259 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M15 compound treatment 883120.0 380000.0 1.01 385830.0 -134000.0 -0.37 0.4562 0.4229 3000958 BCB03_000246 O=c1cccc(o1)c2ccc(C#N)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M16 compound treatment 277440.0 -226000.0 -0.6 219360.0 -301000.0 -0.83 -1.0109 -0.9882 3001177 BCB03_000247 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccco3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M17 compound treatment 476750.0 -26800.0 -0.07 421030.0 -99100.0 -0.27 -0.2429 -0.8638 3092682 BCB03_000248 FC(F)(F)c1ccc(cc1)c2cccc(=O)o2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M18 compound treatment 290680.0 -213000.0 -0.57 410530.0 -110000.0 -0.3 -0.6147 -0.9557 3001178 BCB03_000249 CCOC(=O)C1=CC[C@H](N([C@@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M19 compound treatment 683750.0 180000.0 0.48 529440.0 9350.0 0.03 0.3585 0.7437 3000960 BCB03_000250 FC(F)(F)c1ccccc1c2cccc(=O)o2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M20 compound treatment 734460.0 231000.0 0.62 596160.0 76100.0 0.21 0.5838 0.8965 3001179 BCB03_000251 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)CC[Si](C)(C)C)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M21 compound treatment 344370.0 -159000.0 -0.43 361410.0 -159000.0 -0.44 -0.6087 -0.9999 3000961 BCB03_000252 O=c1cccc(o1)c2ccc3ccccc3c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M22 compound treatment 227260.0 -276000.0 -0.74 221000.0 -299000.0 -0.82 -1.1024 -0.9986 3001245 BCB03_000253 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccn3C(=O)OC(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M23 compound treatment 626520.0 123000.0 0.33 450590.0 -69500.0 -0.19 0.0973 0.2562 3092685 BCB03_000254 O=c1cccc(o1)c2ccco2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 M24 compound treatment 439910.0 -63600.0 -0.17 629440.0 109000.0 0.3 0.0921 0.267 3001246 BCB03_000255 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N01 compound treatment 344540.0 -159000.0 -0.42 793090.0 273000.0 0.75 0.2297 0.2666 3071515 BCB03_000256 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(C)cc3)C(=O)N(C)c4ccccc42 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N02 compound treatment 796690.0 293000.0 0.78 763910.0 244000.0 0.67 1.027 0.997 3188247 BCB03_000257 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)CCCO)C(=O)OCCS(=O)(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N03 compound treatment 290250.0 -213000.0 -0.57 787270.0 267000.0 0.73 0.1158 0.1247 3071516 BCB03_000258 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(C)c4ccccc42 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N04 compound treatment 622490.0 119000.0 0.32 717920.0 198000.0 0.54 0.6087 0.9674 3188248 BCB03_000259 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N05 compound treatment 734450.0 231000.0 0.62 643770.0 124000.0 0.34 0.6762 0.9605 3414062 BCB03_000260 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccccc3)C(=O)N(C)c4ccccc42 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N06 compound treatment 537950.0 34400.0 0.09 381950.0 -138000.0 -0.38 -0.2032 -0.5207 3188250 BCB03_000261 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N07 compound treatment 405530.0 -98000.0 -0.26 740090.0 220000.0 0.6 0.242 0.3676 3188927 BCB03_000262 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)F)C(=O)N(C)c3ccccc32 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N08 compound treatment 224430.0 -279000.0 -0.75 699100.0 179000.0 0.49 -0.1796 -0.2012 3188251 BCB03_000263 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CN4CCCC4)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N09 mock treatment 634490.0 131000.0 0.35 610360.0 90300.0 0.25 0.4226 0.9858 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N10 mock treatment 646970.0 143000.0 0.38 864060.0 344000.0 0.94 0.9386 0.9211 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N11 compound treatment 440930.0 -62600.0 -0.17 696210.0 176000.0 0.48 0.2236 0.4371 3071435 BCB03_000264 COC(=O)C[C@H]1O[C@@]2(C[C@@H]1[Si](C)(C)C)C(=O)N(C)c3ccccc32 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N12 compound treatment 748370.0 245000.0 0.65 794720.0 275000.0 0.75 0.9955 0.9975 3188252 BCB03_000265 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N13 mock treatment 871380.0 368000.0 0.98 888450.0 368000.0 1.01 1.4098 0.9999 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N14 mock treatment 516330.0 12800.0 0.03 783050.0 263000.0 0.72 0.5346 0.7397 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N15 compound treatment 548450.0 44900.0 0.12 848190.0 328000.0 0.9 0.7218 0.7943 3188929 BCB03_000266 COC(=O)C/C=C/C[C@]1(O)C(=O)N(C)c2ccccc21 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N16 compound treatment 771710.0 268000.0 0.72 494720.0 -25400.0 -0.07 0.4572 0.6353 3188253 BCB03_000267 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)c3ccc(CO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N17 compound treatment 601020.0 97500.0 0.26 741960.0 222000.0 0.61 0.6148 0.9281 3188930 BCB03_000268 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO[Si](C(C)C)(C(C)C)C(C)C)nn2)/C=C/C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N18 compound treatment 752130.0 249000.0 0.66 290910.0 -229000.0 -0.63 0.0246 0.0269 3188254 BCB03_000269 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2ccc(CN3CCCC3)cc2)CCCO)C(=O)OCCS(=O)(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N19 compound treatment 811430.0 308000.0 0.82 529920.0 9830.0 0.03 0.6006 0.7299 3071465 BCB03_000270 CCCCNC(=O)c1ccc(C#CC(C)(C)C)c(OC(=O)C)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N20 compound treatment 296880.0 -207000.0 -0.55 283890.0 -236000.0 -0.65 -0.8489 -0.9968 3188255 BCB03_000271 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)CCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N21 compound treatment 700760.0 197000.0 0.53 646290.0 126000.0 0.35 0.6175 0.9793 1952196 BCB03_000272 CCCCNC(=O)c1ccc(C#C[Si](C)(C)C)c(OC(=O)C)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N22 compound treatment 394760.0 -109000.0 -0.29 448130.0 -72000.0 -0.2 -0.3452 -0.9823 3188256 BCB03_000273 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2sc3ccccc3c2Cl)c4ccc(CN5CCCC5)cc4)CCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N23 compound treatment 394200.0 -109000.0 -0.29 592480.0 72400.0 0.2 -0.066 -0.1868 3071510 BCB03_000274 CCCCNC(=O)c1ccc(C#C[Si](C(C)C)(C(C)C)C(C)C)c(OC(=O)C)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 N24 compound treatment 692640.0 189000.0 0.51 603210.0 83100.0 0.23 0.5185 0.9355 3188257 BCB03_000275 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)CCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O01 compound treatment 324770.0 -179000.0 -0.48 269970.0 -250000.0 -0.69 -0.8232 -0.9842 3000963 BCB03_000276 O=c1cccc(CCc2ccccc2)o1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O02 compound treatment 587390.0 83800.0 0.22 283320.0 -237000.0 -0.65 -0.3013 -0.4382 3001247 BCB03_000277 CCOC(=O)C1=CCC(NC1)c2cc3ccccc3[nH]2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O03 compound treatment 497530.0 -6010.0 -0.02 739540.0 219000.0 0.6 0.4147 0.688 3000971 BCB03_000278 [O-][N+](=O)c1ccc(cc1)c2cccc(=O)o2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O04 compound treatment 291000.0 -213000.0 -0.57 259240.0 -261000.0 -0.72 -0.9078 -0.9934 3001248 BCB03_000279 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccccc2[N+](=O)[O-])c3cc4ccccc4[nH]3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O05 compound treatment 414660.0 -88900.0 -0.24 681600.0 162000.0 0.44 0.1457 0.2896 3000972 BCB03_000280 O=c1cccc(/C=C/c2ccccc2)o1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O06 compound treatment 508970.0 5430.0 0.01 469330.0 -50800.0 -0.14 -0.0883 -0.6302 3000756 BCB03_000281 CCOC(=O)C1=CCC(N(CCN2CC(=CCC2c3cc4ccccc4[nH]3)C(=O)OCC)C1)c5cc6ccccc6[nH]5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O07 compound treatment 235460.0 -268000.0 -0.72 268220.0 -252000.0 -0.69 -0.9953 -0.9998 3000973 BCB03_000282 O=c1cccc(o1)c2cccc3ccccc23 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O08 compound treatment 363760.0 -140000.0 -0.37 253700.0 -266000.0 -0.73 -0.7812 -0.9513 3000757 BCB03_000283 CC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O09 compound treatment 321840.0 -182000.0 -0.49 329170.0 -191000.0 -0.52 -0.7138 -0.9993 3000974 BCB03_000284 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O10 compound treatment 517540.0 14000.0 0.04 264480.0 -256000.0 -0.7 -0.4698 -0.6685 3093828 BCB03_000285 Cc1ccc(cc1)[C@@H]2C[C@@H](Sc3ccccc3)[C@@H](CN2S(=O)(=O)c4ccc(C)cc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O11 mock treatment 500370.0 -3170.0 -0.01 488820.0 -31300.0 -0.09 -0.0667 -0.7731 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O12 mock treatment 485120.0 -18400.0 -0.05 339840.0 -180000.0 -0.49 -0.3847 -0.7736 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O13 compound treatment 246210.0 -257000.0 -0.69 331910.0 -188000.0 -0.52 -0.8513 -0.9901 3092701 BCB03_000286 CCOC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)[N+](=O)[O-])c3cccc(c3)[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O14 compound treatment 763930.0 260000.0 0.7 423840.0 -96300.0 -0.26 0.3049 0.4098 3093829 BCB03_000287 Cc1ccc(cc1)C2CC=C(CN2S(=O)(=O)c3ccc(C)cc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O15 compound treatment 316450.0 -187000.0 -0.5 273480.0 -247000.0 -0.68 -0.8321 -0.9888 3092771 BCB03_000288 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccn2)c3ccccn3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O16 compound treatment 402830.0 -101000.0 -0.27 624540.0 104000.0 0.29 0.0125 0.0319 3093830 BCB03_000289 Cc1ccc(cc1)S(=O)(=O)N2CC(=CCC2c3ccccc3)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O17 compound treatment 497480.0 -6060.0 -0.02 535740.0 15600.0 0.04 0.0189 0.4122 3092772 BCB03_000290 COC(=O)c1cccc(c1)[C@@H]2C/C(=C\C(=O)OC(C)C)/O[C@@H](O2)c3cccc(c3)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O18 compound treatment 534110.0 30600.0 0.08 565130.0 45000.0 0.12 0.1452 0.9797 3000760 BCB03_000291 Cc1ccc(cc1)[C@@H]2CC=C([C@@H](N2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O19 compound treatment 404680.0 -98900.0 -0.26 554190.0 34100.0 0.09 -0.1205 -0.4302 3000977 BCB03_000292 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc(C#N)cc2)c3ccc(C#N)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O20 compound treatment 534760.0 31200.0 0.08 544870.0 24800.0 0.07 0.1071 0.9949 3093833 BCB03_000293 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O21 compound treatment 482570.0 -21000.0 -0.06 440920.0 -79200.0 -0.22 -0.1933 -0.8612 3092782 BCB03_000294 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O22 compound treatment 585450.0 81900.0 0.22 434940.0 -85200.0 -0.23 -0.0106 -0.0331 3093834 BCB03_000295 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(C#N)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O23 compound treatment 645660.0 142000.0 0.38 439620.0 -80500.0 -0.22 0.1122 0.2554 3092786 BCB03_000296 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 O24 compound treatment 502290.0 -1250.0 0.0 659930.0 140000.0 0.38 0.2691 0.7009 3093844 BCB03_000297 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P01 compound treatment 490740.0 -12800.0 -0.03 571140.0 51000.0 0.14 0.0749 0.5193 3071725 BCB03_000298 COC(=O)[C@H](Cc1ccc(O)cc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P02 compound treatment 303290.0 -200000.0 -0.53 331200.0 -189000.0 -0.52 -0.7449 -0.9999 3188381 BCB03_000299 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)c3ccc(CO)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P03 compound treatment 234470.0 -269000.0 -0.72 370120.0 -150000.0 -0.41 -0.7993 -0.9651 3188399 BCB03_000300 COC(=O)[C@H](Cc1ccc(O)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P04 compound treatment 341050.0 -162000.0 -0.43 252540.0 -268000.0 -0.73 -0.8263 -0.9685 3070118 BCB03_000301 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)CCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P05 compound treatment 176890.0 -327000.0 -0.87 286970.0 -233000.0 -0.64 -1.0695 -0.9884 3188400 BCB03_000302 COC(=O)[C@H](Cc1ccc(OCC#C)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P06 compound treatment 276430.0 -227000.0 -0.61 394910.0 -125000.0 -0.34 -0.672 -0.9638 3070119 BCB03_000303 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cccc(OC(F)(F)F)c3)CCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P07 compound treatment 228670.0 -275000.0 -0.73 345320.0 -175000.0 -0.48 -0.8584 -0.9787 3188401 BCB03_000304 Oc1ccc(C[C@@H]2N(CC#C)[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P08 compound treatment 296670.0 -207000.0 -0.55 324860.0 -195000.0 -0.54 -0.7697 -0.9999 3188385 BCB03_000305 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3ccc(CN4CCCC4)cc3)CCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P09 compound treatment 265250.0 -238000.0 -0.64 232360.0 -288000.0 -0.79 -1.0086 -0.9943 3188402 BCB03_000306 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccc(OCC#C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P10 compound treatment 213990.0 -290000.0 -0.77 143880.0 -376000.0 -1.03 -1.2772 -0.9898 3188386 BCB03_000307 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P11 mock treatment 325770.0 -178000.0 -0.47 278290.0 -242000.0 -0.66 -0.8052 -0.9865 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P12 mock treatment 428690.0 -74900.0 -0.2 212480.0 -308000.0 -0.84 -0.7385 -0.851 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P13 compound treatment 231130.0 -272000.0 -0.73 155730.0 -364000.0 -1.0 -1.2218 -0.9878 3070937 BCB03_000308 COC(=O)[C@H](Cc1ccc(O)cc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P14 compound treatment 300650.0 -203000.0 -0.54 288640.0 -231000.0 -0.64 -0.8325 -0.9969 3188387 BCB03_000309 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)CCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P15 compound treatment 257400.0 -246000.0 -0.66 208680.0 -311000.0 -0.85 -1.0694 -0.9916 3188528 BCB03_000310 Oc1ccc(C[C@@H]2N3CC4=CCCC=C[C@@H]4[C@H]3[C@@H](Cc5ccccc5)OC2=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P16 compound treatment 261200.0 -242000.0 -0.65 323160.0 -197000.0 -0.54 -0.84 -0.996 3070122 BCB03_000311 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2ccc(CN3CCCC3)cc2)CCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P17 compound treatment 235150.0 -268000.0 -0.72 394720.0 -125000.0 -0.34 -0.7503 -0.9435 3188529 BCB03_000312 COC(=O)[C@H](Cc1ccccc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P18 compound treatment 224500.0 -279000.0 -0.75 185500.0 -335000.0 -0.92 -1.1766 -0.9946 3188390 BCB03_000313 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P19 compound treatment 202100.0 -301000.0 -0.81 262320.0 -258000.0 -0.71 -1.0697 -0.9979 3188530 BCB03_000314 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P20 compound treatment 254730.0 -249000.0 -0.66 464570.0 -55500.0 -0.15 -0.5777 -0.8473 3188503 BCB03_000315 COP(=O)(OC)/N=C\1/CC(=CC(C)N1Cc2cccc(OC(F)(F)F)c2)CCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P21 compound treatment 95520.0 -408000.0 -1.09 55690.0 -464000.0 -1.27 -1.6722 -0.9969 3070940 BCB03_000316 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P22 compound treatment 248010.0 -256000.0 -0.68 341880.0 -178000.0 -0.49 -0.8286 -0.9867 3070124 BCB03_000317 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4ccc(CN5CCCC5)cc4)CCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P23 compound treatment 290640.0 -213000.0 -0.57 266820.0 -253000.0 -0.7 -0.8938 -0.995 3188533 BCB03_000318 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2281 P24 compound treatment 70790.0 -433000.0 -1.16 55130.0 -465000.0 -1.28 -1.72 -0.9988 3188506 BCB03_000319 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)c5ccc(CO)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A01 compound treatment 370520.0 -91900.0 -0.25 741660.0 329000.0 0.9 0.4656 0.4971 3188507 BCB03_000320 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(o3)c4ccc(Cl)c(Cl)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A02 compound treatment 314970.0 -147000.0 -0.39 789530.0 377000.0 1.04 0.4536 0.4095 3071186 BCB03_000321 COc1ccc(cc1)[C@H]2OC[C@@H]3CCC(=O)N23 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A03 compound treatment 211250.0 -251000.0 -0.67 186110.0 -226000.0 -0.62 -0.9137 -0.9993 3070126 BCB03_000322 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A04 compound treatment 269560.0 -193000.0 -0.52 213570.0 -199000.0 -0.55 -0.7503 -0.9996 3071252 BCB03_000323 COc1cccc(C[C@H]2C[C@@H](CO)NC2=O)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A05 compound treatment 361770.0 -101000.0 -0.27 196510.0 -216000.0 -0.59 -0.6093 -0.9361 3070127 BCB03_000324 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A06 compound treatment 213630.0 -249000.0 -0.66 293380.0 -119000.0 -0.33 -0.701 -0.9466 3071181 BCB03_000325 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@]4(O[C@@]23[C@H]5[C@@H]4C(=O)N(C)C5=O)C(=O)C)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A07 compound treatment 211040.0 -251000.0 -0.67 246280.0 -166000.0 -0.46 -0.7973 -0.9822 3070128 BCB03_000326 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3CO[Si](C(C)C)(C(C)C)c31 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A08 compound treatment 440640.0 -21800.0 -0.06 242510.0 -170000.0 -0.47 -0.371 -0.7892 3189172 BCB03_000327 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@@]4(O[C@]23[C@@H]5[C@H]4C(=O)N(C)C5=O)C(=O)C)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A09 compound treatment 267220.0 -195000.0 -0.52 794400.0 382000.0 1.05 0.3729 0.3184 3070129 BCB03_000328 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C3CC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A10 compound treatment 262440.0 -200000.0 -0.53 233360.0 -179000.0 -0.49 -0.7253 -0.9991 3071185 BCB03_000329 COc1ccc(cc1)[C@H]2OC[C@@H]3CC4(CC=CC4)C(=O)N23 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A11 compound treatment 759530.0 297000.0 0.79 423100.0 10700.0 0.03 0.5819 0.7328 3188514 BCB03_000330 CCCCCCc1nc(c2ccc(o2)c3ccc(Cl)c(Cl)c3)c(C)c4CO[Si](C(C)C)(C(C)C)c41 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A12 compound treatment 211970.0 -250000.0 -0.67 196550.0 -216000.0 -0.59 -0.8921 -0.9982 3189173 BCB03_000331 NC(=N)NCc1cn(CCc2c[nH]c3ccccc23)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A13 mock treatment 363230.0 -99200.0 -0.26 194120.0 -218000.0 -0.6 -0.6111 -0.9327 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A14 mock treatment 349330.0 -113000.0 -0.3 464910.0 52500.0 0.14 -0.1117 -0.3337 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A15 compound treatment 496180.0 33700.0 0.09 394340.0 -18100.0 -0.05 0.0286 0.2784 3070178 BCB03_000332 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A16 compound treatment 430760.0 -31700.0 -0.08 255260.0 -157000.0 -0.43 -0.3649 -0.83 3071253 BCB03_000333 COC(=O)c1c(CC[C@@H](CO)NC(=O)N(C)Cc2ccccc2)oc(C(=O)OCC=C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A17 compound treatment 269780.0 -193000.0 -0.51 578360.0 166000.0 0.46 -0.0417 -0.0607 3070179 BCB03_000334 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A18 compound treatment 313610.0 -149000.0 -0.4 736120.0 324000.0 0.89 0.3473 0.3568 3071184 BCB03_000335 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@@H](Cc4ccccc4)C(=O)N23 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A19 compound treatment 276590.0 -186000.0 -0.5 651450.0 239000.0 0.66 0.113 0.1374 3070180 BCB03_000336 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A20 compound treatment 674480.0 212000.0 0.57 187050.0 -225000.0 -0.62 -0.037 -0.0441 3071183 BCB03_000337 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@H](Cc4ccccc4)C(=O)N23 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A21 compound treatment 237190.0 -225000.0 -0.6 360660.0 -51800.0 -0.14 -0.5259 -0.8507 3070181 BCB03_000338 CCCCCCc1nc(C2CC2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A22 compound treatment 750990.0 289000.0 0.77 558310.0 146000.0 0.4 0.8282 0.9535 3189417 BCB03_000339 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(COC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A23 compound treatment 351570.0 -111000.0 -0.3 629810.0 217000.0 0.6 0.2126 0.3192 3188651 BCB03_000340 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 A24 compound treatment 403040.0 -59400.0 -0.16 303360.0 -109000.0 -0.3 -0.3239 -0.9559 3070196 BCB03_000341 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccn2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B01 compound treatment 289890.0 -173000.0 -0.46 335010.0 -77400.0 -0.21 -0.4761 -0.9382 3188662 BCB03_000342 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@@H]2[C@@H](O)Cc3ccccc3)/C=C/C4CC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B02 compound treatment 516430.0 54000.0 0.14 521410.0 109000.0 0.3 0.3136 0.944 3071724 BCB03_000343 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@]4(CO4)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B03 compound treatment 413860.0 -48600.0 -0.13 491610.0 79200.0 0.22 0.062 0.2449 3188663 BCB03_000344 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B04 compound treatment 709830.0 247000.0 0.66 596600.0 184000.0 0.51 0.8248 0.9913 3071727 BCB03_000345 C[C@]12COC[C@@]2(C=C(Br)[C@@H]3C1)C(=O)[C@@]43CO4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B05 compound treatment 791010.0 329000.0 0.88 196440.0 -216000.0 -0.59 0.2013 0.1901 3070955 BCB03_000346 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B06 compound treatment 660420.0 198000.0 0.53 551850.0 139000.0 0.38 0.6446 0.9874 3071766 BCB03_000347 CCCCC[C@H]1OC[C@@]2(C=C(Br)[C@@H]3CC12)C(=O)[C@@]43CO4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B07 compound treatment 296840.0 -166000.0 -0.44 422610.0 10200.0 0.03 -0.293 -0.661 3188666 BCB03_000348 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B08 compound treatment 535300.0 72900.0 0.19 578570.0 166000.0 0.46 0.4602 0.9279 3071767 BCB03_000349 CC1(C)OC[C@@]2(C=C(Br)[C@@H]3C[C@H]12)C(=O)[C@@]43CO4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B09 compound treatment 553300.0 90900.0 0.24 209370.0 -203000.0 -0.56 -0.2226 -0.3661 3188667 BCB03_000350 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4ccccc4Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B10 compound treatment 491460.0 29000.0 0.08 574460.0 162000.0 0.44 0.3694 0.818 3071770 BCB03_000351 BrC1=C[C@]23COCC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B11 compound treatment 727930.0 265000.0 0.71 216890.0 -196000.0 -0.54 0.1219 0.137 3188668 BCB03_000352 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/c2ccccc2)[C@@H](O)Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B12 compound treatment 90890.0 -372000.0 -0.99 17280.0 -395000.0 -1.08 -1.4688 -0.999 3071774 BCB03_000353 C=CCC1=C[C@H]2[C@H]([C@H]3C=C[C@]2(CC=C)C(=O)[C@@]43CO4)[C@@]5(CO5)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B13 mock treatment 383880.0 -78600.0 -0.21 361370.0 -51000.0 -0.14 -0.2475 -0.9807 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B14 mock treatment 363570.0 -98900.0 -0.26 219610.0 -193000.0 -0.53 -0.561 -0.9484 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B15 compound treatment 236370.0 -226000.0 -0.6 328320.0 -84100.0 -0.23 -0.5902 -0.913 3070996 BCB03_000354 O[C@@H](Cc1ccccc1)[C@@H](/C=C/c2ccccc2)N(CC#C)Cc3ccccc3Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B16 compound treatment 13620.0 -449000.0 -1.2 15700.0 -397000.0 -1.09 -1.6178 -0.9989 3188527 BCB03_000355 CC1=C[C@]2(CO)C(=O)[C@]3(CO3)[C@H]1[C@@H]4[C@@]5(CO5)C(=O)C(=C[C@@]42C)CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B17 compound treatment 136580.0 -326000.0 -0.87 339800.0 -72600.0 -0.2 -0.7564 -0.8471 3070997 BCB03_000356 CCCC/C=C/[C@H]([C@@H](O)Cc1ccccc1)N(CC#Cc2ccccc2)Cc3ccccc3Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B18 compound treatment 250890.0 -212000.0 -0.57 441440.0 29000.0 0.08 -0.3432 -0.6014 3070938 BCB03_000357 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B19 compound treatment 591040.0 129000.0 0.34 189470.0 -223000.0 -0.61 -0.1899 -0.2706 3071055 BCB03_000358 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B20 compound treatment 183430.0 -279000.0 -0.75 208610.0 -204000.0 -0.56 -0.9226 -0.99 3070939 BCB03_000359 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)c4ccccc4)C2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B21 compound treatment 212520.0 -250000.0 -0.67 276550.0 -136000.0 -0.37 -0.7358 -0.9622 3188794 BCB03_000360 O[C@@H](Cc1ccccc1)[C@H](NCc2cccc(Cl)c2)/C=C/C3CC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B22 compound treatment 246470.0 -216000.0 -0.58 245070.0 -167000.0 -0.46 -0.7328 -0.9936 3188531 BCB03_000361 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Oc4ccccc4)cc3)C2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B23 compound treatment 448590.0 -13800.0 -0.04 578980.0 167000.0 0.46 0.2972 0.6478 3188796 BCB03_000362 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4cccc(Cl)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 B24 compound treatment 675890.0 213000.0 0.57 292740.0 -120000.0 -0.33 0.1708 0.2596 3188532 BCB03_000363 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)C(F)(F)F)C2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C01 compound treatment 751780.0 289000.0 0.77 711050.0 299000.0 0.82 1.1262 0.9996 3070235 BCB03_000364 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4cc(C)c(OC)c(C)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C02 compound treatment 623430.0 161000.0 0.43 665150.0 253000.0 0.69 0.7947 0.9735 3189039 BCB03_000365 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C03 compound treatment 515640.0 53200.0 0.14 626650.0 214000.0 0.59 0.5164 0.8534 3070236 BCB03_000366 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(OC)nc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C04 compound treatment 391770.0 -70700.0 -0.19 555240.0 143000.0 0.39 0.1438 0.3305 3070086 BCB03_000367 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(CCCNC(=N)N)nn2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C05 compound treatment 570850.0 108000.0 0.29 272320.0 -140000.0 -0.38 -0.0672 -0.1396 3188655 BCB03_000368 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3[C@@H](O[Si](C(C)C)(C(C)C)c31)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C06 compound treatment 644520.0 182000.0 0.49 346290.0 -66100.0 -0.18 0.2155 0.4152 3070191 BCB03_000369 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(Cc3ccccc3)nn2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C07 compound treatment 308290.0 -154000.0 -0.41 454360.0 41900.0 0.12 -0.2097 -0.4905 3188656 BCB03_000370 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)C4CC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C08 compound treatment 323430.0 -139000.0 -0.37 243040.0 -169000.0 -0.46 -0.5913 -0.9938 3071180 BCB03_000371 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccn3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C09 compound treatment 630040.0 168000.0 0.45 235480.0 -177000.0 -0.49 -0.0269 -0.0408 3188772 BCB03_000372 CCCCCCc1nc(CCCc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)c4ccccc4)cc5[C@@H](O[Si](C(C)C)(C(C)C)c51)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C10 compound treatment 684650.0 222000.0 0.59 241190.0 -171000.0 -0.47 0.0873 0.1153 3070134 BCB03_000373 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)C3(O)CCCCC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C11 mock treatment 417300.0 -45100.0 -0.12 352480.0 -59900.0 -0.16 -0.2016 -0.9883 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C12 mock treatment 292970.0 -169000.0 -0.45 482950.0 70500.0 0.19 -0.1831 -0.372 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C13 compound treatment 703680.0 241000.0 0.64 356530.0 -55900.0 -0.15 0.3471 0.5241 3070242 BCB03_000374 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C14 compound treatment 305370.0 -157000.0 -0.42 238440.0 -174000.0 -0.48 -0.6344 -0.9979 3070089 BCB03_000375 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C15 mock treatment 365040.0 -97400.0 -0.26 722360.0 310000.0 0.85 0.4178 0.4695 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C16 mock treatment 705140.0 243000.0 0.65 354010.0 -58400.0 -0.16 0.345 0.5166 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C17 compound treatment 423870.0 -38600.0 -0.1 377220.0 -35200.0 -0.1 -0.1412 -0.9995 3070245 BCB03_000376 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C18 compound treatment 394260.0 -68200.0 -0.18 323290.0 -89100.0 -0.24 -0.3018 -0.9894 3071179 BCB03_000377 CC(C)[C@@H](C(=O)O)n1cc(nn1)C2(O)CCCCC2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C19 compound treatment 274910.0 -188000.0 -0.5 443270.0 30900.0 0.08 -0.2943 -0.5793 3070527 BCB03_000378 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)cc(OC)c1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C20 compound treatment 519010.0 56600.0 0.15 229650.0 -183000.0 -0.5 -0.2479 -0.4732 3414058 BCB03_000379 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C21 compound treatment 465600.0 3170.0 0.01 460680.0 48300.0 0.13 0.0997 0.7507 3070530 BCB03_000380 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)C4CC4)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C22 compound treatment 757770.0 295000.0 0.79 267150.0 -145000.0 -0.4 0.2758 0.312 3189555 BCB03_000381 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C23 compound treatment 422080.0 -40400.0 -0.11 278160.0 -134000.0 -0.37 -0.3368 -0.8772 3070081 BCB03_000382 CC(C)[Si]1(OCc2c1c(nc(c3ccc(o3)c4ccc(Cl)c(Cl)c4)c2C)c5ccccc5)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 C24 compound treatment 359650.0 -103000.0 -0.27 547840.0 135000.0 0.37 0.0688 0.1488 3189558 BCB03_000383 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D01 compound treatment 677390.0 215000.0 0.57 516960.0 105000.0 0.29 0.6089 0.9487 3071060 BCB03_000384 O[C@@H](Cc1ccccc1)[C@H](NCc2ccccc2Br)/C=C/c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D02 compound treatment 535530.0 73100.0 0.2 635440.0 223000.0 0.61 0.571 0.8885 3070941 BCB03_000385 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4[nH]ccc4c3)C2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D03 compound treatment 213840.0 -249000.0 -0.66 265040.0 -147000.0 -0.4 -0.7556 -0.9718 3188797 BCB03_000386 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC=C3CN2Cc4cccc(Cl)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D04 compound treatment 352450.0 -110000.0 -0.29 240820.0 -172000.0 -0.47 -0.5408 -0.9742 3070942 BCB03_000387 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3cccc4[nH]ccc34)C2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D05 compound treatment 252960.0 -209000.0 -0.56 203680.0 -209000.0 -0.57 -0.8008 -0.9999 3188798 BCB03_000388 COC1(C)CN(Cc2ccccc2Br)[C@H](/C=C/c3ccccc3)[C@H](Cc4ccccc4)O1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D06 compound treatment 160250.0 -302000.0 -0.81 713620.0 301000.0 0.83 0.014 0.0121 3070943 BCB03_000389 CC(C)Oc1ccc(cc1)C(=O)N2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D07 compound treatment 345700.0 -117000.0 -0.31 500640.0 88200.0 0.24 -0.0492 -0.1246 3188799 BCB03_000390 CN1C(=O)C2C3[C@H]([C@@H](O)Cc4ccccc4)N(Cc5cccc(Cl)c5)CC3=CC(C6CC6)C2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D08 compound treatment 279040.0 -183000.0 -0.49 216870.0 -196000.0 -0.54 -0.726 -0.999 3188537 BCB03_000391 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Br)cc3)C2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D09 compound treatment 748000.0 286000.0 0.76 454880.0 42500.0 0.12 0.6218 0.8058 3071066 BCB03_000392 O[C@@H](Cc1ccccc1)[C@H](N(CC#C)CC2=CCCCC2)c3ccccc3Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D10 compound treatment 314720.0 -148000.0 -0.39 269230.0 -143000.0 -0.39 -0.5569 -1.0 3070952 BCB03_000393 CC(C)Cc1ccc(CN2CC[C@@H](N)C2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D11 mock treatment 802100.0 340000.0 0.91 339750.0 -72700.0 -0.2 0.5005 0.5388 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D12 mock treatment 200330.0 -262000.0 -0.7 543110.0 131000.0 0.36 -0.2413 -0.3067 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D13 compound treatment 313120.0 -149000.0 -0.4 446000.0 33600.0 0.09 -0.2168 -0.5296 3071068 BCB03_000394 O=C(Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4ccccc4)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D14 compound treatment 286270.0 -176000.0 -0.47 255570.0 -157000.0 -0.43 -0.6372 -0.999 3070953 BCB03_000395 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccccc3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D15 mock treatment 249490.0 -213000.0 -0.57 284910.0 -128000.0 -0.35 -0.6497 -0.9728 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D16 mock treatment 273360.0 -189000.0 -0.51 501230.0 88800.0 0.24 -0.1847 -0.3293 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D17 compound treatment 165440.0 -297000.0 -0.79 241280.0 -171000.0 -0.47 -0.8931 -0.9687 3071112 BCB03_000396 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4cccc(Cl)c4)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D18 compound treatment 449970.0 -12500.0 -0.03 190720.0 -222000.0 -0.61 -0.4539 -0.7447 3070954 BCB03_000397 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)c3ccccc3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D19 compound treatment 247280.0 -215000.0 -0.57 206090.0 -206000.0 -0.57 -0.8069 -1.0 3188804 BCB03_000398 Clc1cccc(CN2CC3=CCCC=CC3[C@@H]2[C@H](Cc4ccccc4)OC(=O)C=C)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D20 compound treatment 211420.0 -251000.0 -0.67 15950.0 -396000.0 -1.09 -1.2437 -0.9729 3188664 BCB03_000399 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)Nc3ccccc3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D21 compound treatment 151130.0 -311000.0 -0.83 114180.0 -298000.0 -0.82 -1.1669 -1.0 3071454 BCB03_000400 CCC1=C2CN(Cc3ccccc3Br)[C@@H]([C@@H](O)Cc4ccccc4)C2C=CCC1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D22 compound treatment 392520.0 -69900.0 -0.19 344020.0 -68400.0 -0.19 -0.2648 -1.0 3188665 BCB03_000401 CC(C)Oc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D23 compound treatment 332770.0 -130000.0 -0.35 193920.0 -218000.0 -0.6 -0.6691 -0.9659 3071455 BCB03_000402 CCC1=C2CN(Cc3ccccc3)[C@H](C2C=CCC1)C(=O)Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 D24 compound treatment 329150.0 -133000.0 -0.36 313050.0 -99400.0 -0.27 -0.4446 -0.9914 3070994 BCB03_000403 CC(C)Oc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E01 mock treatment 626000.0 164000.0 0.44 509680.0 97300.0 0.27 0.4977 0.9721 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E02 mock treatment 802370.0 340000.0 0.91 569220.0 157000.0 0.43 0.9464 0.9419 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E03 compound treatment 822120.0 360000.0 0.96 207550.0 -205000.0 -0.56 0.2816 0.253 3189040 BCB03_000404 COc1c(C)cc(cc1C)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E04 compound treatment 630300.0 168000.0 0.45 296130.0 -116000.0 -0.32 0.0913 0.1659 3189560 BCB03_000405 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H]5CCCN5C2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E05 compound treatment 752960.0 291000.0 0.78 305480.0 -107000.0 -0.29 0.3411 0.4112 3189041 BCB03_000406 COc1ccc(cn1)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E06 compound treatment 229690.0 -233000.0 -0.62 566780.0 154000.0 0.42 -0.1399 -0.186 3189559 BCB03_000407 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H]5CCCN5C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E07 compound treatment 784870.0 322000.0 0.86 506250.0 93800.0 0.26 0.7911 0.8801 3189042 BCB03_000408 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E08 compound treatment 605570.0 143000.0 0.38 581400.0 169000.0 0.46 0.5984 0.9954 3189043 BCB03_000409 N[C@@H](Cc1ccccc1)Cn2cc(nn2)C3(O)CCCCC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E09 mock treatment 343570.0 -119000.0 -0.32 253710.0 -159000.0 -0.44 -0.5326 -0.9879 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E10 mock treatment 559200.0 96800.0 0.26 657860.0 245000.0 0.67 0.6592 0.9134 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E11 compound treatment 720420.0 258000.0 0.69 300500.0 -112000.0 -0.31 0.27 0.3579 3070137 BCB03_000410 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E12 compound treatment 230140.0 -232000.0 -0.62 199890.0 -213000.0 -0.58 -0.8513 -0.9995 3070143 BCB03_000411 N[C@@H](Cc1ccccc1)Cn2cc(nn2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E13 compound treatment 225660.0 -237000.0 -0.63 784170.0 372000.0 1.02 0.2745 0.2286 3189044 BCB03_000412 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E14 compound treatment 563360.0 101000.0 0.27 423940.0 11500.0 0.03 0.213 0.7847 3189695 BCB03_000413 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E15 compound treatment 782520.0 320000.0 0.85 301220.0 -111000.0 -0.31 0.3887 0.4281 3189045 BCB03_000414 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)C4CC4)c5ccccc5)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E16 compound treatment 322010.0 -140000.0 -0.38 300690.0 -112000.0 -0.31 -0.4821 -0.995 3071393 BCB03_000415 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cnnn3C[C@H](Cc4ccccc4)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E17 mock treatment 293870.0 -169000.0 -0.45 524030.0 112000.0 0.31 -0.1017 -0.1867 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E18 mock treatment 234240.0 -228000.0 -0.61 293410.0 -119000.0 -0.33 -0.662 -0.9573 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E19 compound treatment 243200.0 -219000.0 -0.59 476960.0 64500.0 0.18 -0.2888 -0.472 3189046 BCB03_000416 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E20 compound treatment 776660.0 314000.0 0.84 483370.0 71000.0 0.19 0.7312 0.8487 3071396 BCB03_000417 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](C)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E21 compound treatment 269810.0 -193000.0 -0.51 292640.0 -120000.0 -0.33 -0.5963 -0.9766 3189047 BCB03_000418 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E22 compound treatment 577600.0 115000.0 0.31 740760.0 328000.0 0.9 0.8549 0.8976 3187595 BCB03_000419 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](NC2=O)C(C)C)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E23 compound treatment 429570.0 -32900.0 -0.09 403450.0 -8960.0 -0.02 -0.0795 -0.8717 3189169 BCB03_000420 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 E24 compound treatment 814740.0 352000.0 0.94 249830.0 -163000.0 -0.45 0.3498 0.3358 3187594 BCB03_000421 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F01 mock treatment 827000.0 365000.0 0.97 244820.0 -168000.0 -0.46 0.3632 0.3372 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F02 mock treatment 246250.0 -216000.0 -0.58 335590.0 -76800.0 -0.21 -0.5574 -0.9068 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F03 compound treatment 209630.0 -253000.0 -0.68 376290.0 -36100.0 -0.1 -0.5476 -0.8024 3071456 BCB03_000422 C/C=C\[C@@H](NCc1ccccc1Br)[C@@H](O)Cc2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F04 compound treatment 525690.0 63300.0 0.17 392800.0 -19600.0 -0.05 0.0814 0.459 3070995 BCB03_000423 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4OCOc4c3)C2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F05 compound treatment 365160.0 -97300.0 -0.26 205460.0 -207000.0 -0.57 -0.5855 -0.9371 3071457 BCB03_000424 CC(=CCN[C@H](CO)c1ccccc1)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F06 compound treatment 560050.0 97600.0 0.26 209350.0 -203000.0 -0.56 -0.2098 -0.341 2133134 BCB03_000425 CCCCC(=O)N(CCN1CCOCC1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F07 compound treatment 306290.0 -156000.0 -0.42 303220.0 -109000.0 -0.3 -0.5069 -0.9869 3071458 BCB03_000426 CC(=CCN(CC#C)[C@H](CO)c1ccccc1)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F08 compound treatment 390400.0 -72000.0 -0.19 393360.0 -19100.0 -0.05 -0.173 -0.8678 2133147 BCB03_000427 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCCO4)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F09 mock treatment 777930.0 315000.0 0.84 783150.0 371000.0 1.02 1.3156 0.9956 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F10 mock treatment 485340.0 22900.0 0.06 463480.0 51100.0 0.14 0.1424 0.9309 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F11 compound treatment 202370.0 -260000.0 -0.69 122160.0 -290000.0 -0.8 -1.0546 -0.9977 3187737 BCB03_000428 CC(=CCN(CC#Cc1ccccc1)[C@H](CO)c2ccccc2)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F12 compound treatment 625940.0 164000.0 0.44 185510.0 -227000.0 -0.62 -0.1317 -0.1731 3188671 BCB03_000429 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCCc3c[nH]c4ccccc34)[C@@H]2O)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F13 compound treatment 147200.0 -315000.0 -0.84 249940.0 -162000.0 -0.45 -0.9108 -0.9559 3071460 BCB03_000430 O=C1OC[C@@H](c2ccccc2)n3cc(/C=C/c4ccccc4)cc13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F14 compound treatment 597250.0 135000.0 0.36 193840.0 -219000.0 -0.6 -0.1697 -0.2425 2129060 BCB03_000431 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCC3CCCCC3)[C@@H]2O)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F15 compound treatment 304180.0 -158000.0 -0.42 213330.0 -199000.0 -0.55 -0.6854 -0.9919 3071461 BCB03_000432 CC(=C)C/1CN([C@H](CO)c2ccccc2)C(=O)\C1=C/c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F16 compound treatment 189250.0 -273000.0 -0.73 362120.0 -50300.0 -0.14 -0.6136 -0.8262 2129057 BCB03_000433 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC[C@@H]3CCCO3)[C@@H]2O)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F17 mock treatment 230950.0 -231000.0 -0.62 192860.0 -220000.0 -0.6 -0.8634 -0.9999 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F18 mock treatment 319200.0 -143000.0 -0.38 519740.0 107000.0 0.29 -0.0622 -0.1287 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F19 compound treatment 540760.0 78300.0 0.21 303130.0 -109000.0 -0.3 -0.0642 -0.1756 3071462 BCB03_000434 OCC(/C=C/c1ccccc1)N(CC#C)C(C(=O)O)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F20 compound treatment 267210.0 -195000.0 -0.52 180070.0 -232000.0 -0.64 -0.8198 -0.995 2129061 BCB03_000435 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC3CCCCCC3)[C@@H]2O)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F21 compound treatment 236550.0 -226000.0 -0.6 260360.0 -152000.0 -0.42 -0.7218 -0.9838 3071463 BCB03_000436 C/C=C/CN([C@H](CO[Si](C)(C)C(C)(C)C)c1ccccc1)C(=O)C#Cc2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F22 compound treatment 298360.0 -164000.0 -0.44 259200.0 -153000.0 -0.42 -0.6073 -0.9998 2129067 BCB03_000437 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccccc3F)[C@@H]2O)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F23 compound treatment 598810.0 136000.0 0.36 282420.0 -130000.0 -0.36 0.0052 0.0102 3071464 BCB03_000438 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 F24 compound treatment 167090.0 -295000.0 -0.79 197450.0 -215000.0 -0.59 -0.9751 -0.9898 2129068 BCB03_000439 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccc(F)cc3)[C@@H]2O)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G01 compound treatment 522370.0 59900.0 0.16 266820.0 -146000.0 -0.4 -0.1694 -0.3935 3189170 BCB03_000440 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)cc(OC)c1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G02 compound treatment 588000.0 126000.0 0.34 278010.0 -134000.0 -0.37 -0.0238 -0.0477 3187594 BCB03_000441 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G03 mock treatment 377040.0 -85400.0 -0.23 356960.0 -55500.0 -0.15 -0.2689 -0.9807 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G04 mock treatment 886850.0 424000.0 1.13 201710.0 -211000.0 -0.58 0.3925 0.3084 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G05 compound treatment 227590.0 -235000.0 -0.63 228420.0 -184000.0 -0.51 -0.8007 -0.9942 3189171 BCB03_000442 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G06 compound treatment 462640.0 205.0 0.0 610040.0 198000.0 0.54 0.384 0.7078 3187597 BCB03_000443 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](NC2=O)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G07 compound treatment 271710.0 -191000.0 -0.51 565710.0 153000.0 0.42 -0.0626 -0.0948 3071182 BCB03_000444 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G08 compound treatment 749310.0 287000.0 0.77 687170.0 275000.0 0.75 1.0752 1.0 3189696 BCB03_000445 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G09 compound treatment 148520.0 -314000.0 -0.84 428990.0 16600.0 0.05 -0.5607 -0.6677 3189286 BCB03_000446 CC(C)[Si]1(O[C@H](c2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G10 compound treatment 603720.0 141000.0 0.38 385840.0 -26600.0 -0.07 0.2153 0.56 3187593 BCB03_000447 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G11 compound treatment 128920.0 -334000.0 -0.89 341520.0 -70900.0 -0.19 -0.7675 -0.8417 3189287 BCB03_000448 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G12 compound treatment 191200.0 -271000.0 -0.72 195120.0 -217000.0 -0.6 -0.9341 -0.9953 3414059 BCB03_000449 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(Cc5ccccc5)C2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G13 compound treatment 379160.0 -83300.0 -0.22 116000.0 -296000.0 -0.81 -0.7327 -0.8685 3189288 BCB03_000450 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G14 compound treatment 196980.0 -265000.0 -0.71 175790.0 -237000.0 -0.65 -0.9607 -0.999 3414060 BCB03_000451 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(nn4)C5(CCCCC5)NC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G15 compound treatment 144610.0 -318000.0 -0.85 134080.0 -278000.0 -0.76 -1.1406 -0.9986 3189289 BCB03_000452 COc1cc(Cc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5)cc(OC)c1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G16 compound treatment 608800.0 146000.0 0.39 450140.0 37700.0 0.1 0.3497 0.8646 3189561 BCB03_000453 CN1Cc2cn(C[C@H](Cc3ccccc3)NC(=O)c4cc(c(CC[C@@H](CO)NC1=O)o4)S(=O)(=O)c5ccc(C)cc5)nn2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G17 compound treatment 419950.0 -42500.0 -0.11 364490.0 -47900.0 -0.13 -0.1733 -0.9973 3189171 BCB03_000454 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G18 compound treatment 511630.0 49200.0 0.13 202000.0 -210000.0 -0.58 -0.3156 -0.5327 3189290 BCB03_000455 COc1ccc(cc1)[C@H]2OC[C@@H]3CC(CC=C)(CC=C)C(=O)N23 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G19 mock treatment 509930.0 47500.0 0.13 338570.0 -73800.0 -0.2 -0.0536 -0.2243 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G20 mock treatment 192880.0 -270000.0 -0.72 200490.0 -212000.0 -0.58 -0.9205 -0.9944 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G21 compound treatment 403170.0 -59300.0 -0.16 255580.0 -157000.0 -0.43 -0.4164 -0.9077 3071182 BCB03_000456 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G22 compound treatment 326570.0 -136000.0 -0.36 263960.0 -148000.0 -0.41 -0.5448 -0.9983 3071255 BCB03_000457 NC(=N)NCC#C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G23 compound treatment 239610.0 -223000.0 -0.6 445040.0 32600.0 0.09 -0.3575 -0.594 3188910 BCB03_000458 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)c5ccc(o5)c6ccc(Cl)c(Cl)c6)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 G24 compound treatment 612120.0 150000.0 0.4 202130.0 -210000.0 -0.58 -0.1255 -0.1787 3189419 BCB03_000459 OC(=O)CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H01 compound treatment 238360.0 -224000.0 -0.6 242100.0 -170000.0 -0.47 -0.7538 -0.9925 3071464 BCB03_000460 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H02 compound treatment 543560.0 81100.0 0.22 516700.0 104000.0 0.29 0.3557 0.9906 3071064 BCB03_000461 CCCC(=O)N(CCc1c[nH]c2ccccc12)[C@@H]3CC(=C[C@H](Oc4c(I)cc(CO)cc4OC)[C@H]3O)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H03 mock treatment 264180.0 -198000.0 -0.53 271680.0 -141000.0 -0.39 -0.6476 -0.988 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H04 mock treatment 811390.0 349000.0 0.93 158440.0 -254000.0 -0.7 0.166 0.1426 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H05 compound treatment 321050.0 -141000.0 -0.38 320040.0 -92400.0 -0.25 -0.4464 -0.9812 3071517 BCB03_000462 CC(=C)C1C(=C)CN([C@H](CO)c2ccccc2)C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H06 compound treatment 260830.0 -202000.0 -0.54 480480.0 68100.0 0.19 -0.2486 -0.4362 2133032 BCB03_000463 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4ccc(cc4)C(F)(F)F)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H07 compound treatment 285130.0 -177000.0 -0.47 235600.0 -177000.0 -0.49 -0.6781 -0.9999 3187880 BCB03_000464 CC(C)(C)OC(=O)N(CC#C)[C@H](CO)c1ccccc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H08 compound treatment 250050.0 -212000.0 -0.57 698650.0 286000.0 0.79 0.1545 0.1595 2133035 BCB03_000465 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H09 compound treatment 135940.0 -326000.0 -0.87 28390.0 -384000.0 -1.05 -1.3621 -0.9956 3071519 BCB03_000466 CC(=CCN([C@H](CO)c1ccccc1)C(=O)C#Cc2ccccc2)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H10 compound treatment 470080.0 7650.0 0.02 387520.0 -24900.0 -0.07 -0.0339 -0.4751 2133267 BCB03_000467 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(Cc3ccc(F)cc3)C(=O)C4CCCO4)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H11 compound treatment 191870.0 -271000.0 -0.72 386400.0 -26000.0 -0.07 -0.5615 -0.7732 3071520 BCB03_000468 OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H12 compound treatment 144730.0 -318000.0 -0.85 231850.0 -181000.0 -0.5 -0.9506 -0.9672 2133153 BCB03_000469 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCOC4)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H13 compound treatment 652580.0 190000.0 0.51 220400.0 -192000.0 -0.53 -0.0136 -0.0186 3071521 BCB03_000470 CC(C)(C)[Si](C)(C)OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H14 compound treatment 337950.0 -124000.0 -0.33 512730.0 100000.0 0.28 -0.0404 -0.0935 2132929 BCB03_000471 CC/C=C/C(=O)N(C[C@@H]1CCCO1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H15 compound treatment 159040.0 -303000.0 -0.81 361170.0 -51200.0 -0.14 -0.6725 -0.8176 3071522 BCB03_000472 O=C1OC[C@H](N2CC(=CC21)/C=C/c3ccccc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H16 compound treatment 605180.0 143000.0 0.38 257660.0 -155000.0 -0.42 -0.0308 -0.054 2133065 BCB03_000473 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(C3CCCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H17 compound treatment 671250.0 209000.0 0.56 391220.0 -21200.0 -0.06 0.3532 0.6299 3071523 BCB03_000474 OCC(/C=C/c1ccccc1)N(CC#C)Cc2ccccc2Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H18 compound treatment 339680.0 -123000.0 -0.33 740540.0 328000.0 0.9 0.4052 0.4226 2133224 BCB03_000475 CCCCC(=O)N(Cc1ccccc1F)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H19 mock treatment 440750.0 -21700.0 -0.06 380980.0 -31400.0 -0.09 -0.102 -0.9812 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H20 mock treatment 468010.0 5580.0 0.01 676220.0 264000.0 0.72 0.5227 0.7215 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H21 compound treatment 321290.0 -141000.0 -0.38 217070.0 -195000.0 -0.54 -0.6458 -0.9851 3071524 BCB03_000476 OCC1C=C(CN1Cc2ccccc2Br)/C=C/c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H22 compound treatment 222310.0 -240000.0 -0.64 296800.0 -116000.0 -0.32 -0.678 -0.9474 2133510 BCB03_000477 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCc3cccc(F)c3)C(=O)CCC4CCCC4)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H23 compound treatment 376350.0 -86100.0 -0.23 205320.0 -207000.0 -0.57 -0.5646 -0.9206 3414064 BCB03_000478 O=S1(=O)N2CCC[C@@H]2[C@@H](Oc3ccccc31)C#C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 H24 compound treatment 229960.0 -232000.0 -0.62 312590.0 -99800.0 -0.27 -0.6329 -0.9324 2128988 BCB03_000479 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H]3O[C@@H]32)C(=O)NCCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I01 compound treatment 799200.0 337000.0 0.9 548030.0 136000.0 0.37 0.8993 0.9238 3070742 BCB03_000480 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I02 compound treatment 171520.0 -291000.0 -0.78 595260.0 183000.0 0.5 -0.1945 -0.2102 3189420 BCB03_000481 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@](Cc4ccccc4)(C(=O)OCC=C)C(=O)N23 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I03 compound treatment 202990.0 -259000.0 -0.69 495970.0 83600.0 0.23 -0.3278 -0.4491 3070750 BCB03_000482 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I04 compound treatment 813520.0 351000.0 0.94 470460.0 58000.0 0.16 0.7758 0.8156 1035256 BCB03_000483 C#CCNCc1ccccc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I05 mock treatment 458280.0 -4150.0 -0.01 437800.0 25400.0 0.07 0.0414 0.5871 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I06 mock treatment 289840.0 -173000.0 -0.46 378520.0 -33900.0 -0.09 -0.3918 -0.833 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I07 compound treatment 155070.0 -307000.0 -0.82 542030.0 130000.0 0.36 -0.3289 -0.3676 3188915 BCB03_000484 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I08 compound treatment 655050.0 193000.0 0.51 174600.0 -238000.0 -0.65 -0.0979 -0.1178 3071258 BCB03_000485 CC(C)[C@H](N=[N+]=[N-])C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I09 compound treatment 342200.0 -120000.0 -0.32 441540.0 29100.0 0.08 -0.1705 -0.5153 3070808 BCB03_000486 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)c6ccccc6)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I10 compound treatment 303680.0 -159000.0 -0.42 254170.0 -158000.0 -0.43 -0.607 -0.9999 3189550 BCB03_000487 COc1cccc(C[C@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I11 compound treatment 273370.0 -189000.0 -0.5 223950.0 -188000.0 -0.52 -0.7229 -0.9999 3070078 BCB03_000488 CC[C@@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccc(Oc4ccccc4)cc3)c5cc(C)c(OC)c(C)c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I12 compound treatment 160590.0 -302000.0 -0.81 241190.0 -171000.0 -0.47 -0.9025 -0.967 3189551 BCB03_000489 COc1cccc(C[C@@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I13 compound treatment 303330.0 -159000.0 -0.42 552900.0 140000.0 0.39 -0.0278 -0.0484 3070690 BCB03_000490 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C(=C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I14 compound treatment 360770.0 -102000.0 -0.27 743130.0 331000.0 0.91 0.45 0.4748 3071267 BCB03_000491 CN(C)S(=O)(=O)NCC#C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I15 compound treatment 613150.0 151000.0 0.4 277040.0 -135000.0 -0.37 0.0219 0.0399 3071259 BCB03_000492 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#Cc4ccccc4)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I16 compound treatment 224800.0 -238000.0 -0.63 239680.0 -173000.0 -0.47 -0.7841 -0.9897 3189556 BCB03_000493 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I17 compound treatment 441760.0 -20700.0 -0.06 434240.0 21800.0 0.06 0.0033 0.0408 3071266 BCB03_000494 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCc4ccccc4)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I18 compound treatment 363740.0 -98700.0 -0.26 298470.0 -114000.0 -0.31 -0.4076 -0.9964 3188911 BCB03_000495 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I19 compound treatment 729920.0 267000.0 0.71 522240.0 110000.0 0.3 0.7184 0.9264 3189415 BCB03_000496 CCCCCCC#C[Si](O[C@@H](C#C)c1ccccc1)(C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I20 compound treatment 624120.0 162000.0 0.43 460810.0 48400.0 0.13 0.3993 0.8838 3188912 BCB03_000497 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](C)Cn3cc(CN(C)C2=O)nn3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I21 mock treatment 422320.0 -40100.0 -0.11 357550.0 -54900.0 -0.15 -0.1823 -0.9861 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I22 mock treatment 785190.0 323000.0 0.86 314930.0 -97500.0 -0.27 0.4203 0.4657 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I23 compound treatment 293120.0 -169000.0 -0.45 217280.0 -195000.0 -0.54 -0.6986 -0.9964 3189416 BCB03_000498 CCCCCCC#C[Si](OCC#CC)(C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 I24 compound treatment 431840.0 -30600.0 -0.08 263680.0 -149000.0 -0.41 -0.3465 -0.8321 3188913 BCB03_000499 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J01 compound treatment 447710.0 -14700.0 -0.04 314120.0 -98300.0 -0.27 -0.2186 -0.8017 3071594 BCB03_000500 O=S1(=O)N2CCC[C@H]2[C@H](Oc3ccccc31)C#C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J02 compound treatment 457640.0 -4790.0 -0.01 309290.0 -103000.0 -0.28 -0.2092 -0.7383 3187871 BCB03_000501 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)N(Cc3ccco3)C(=O)Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J03 compound treatment 357640.0 -105000.0 -0.28 327790.0 -84600.0 -0.23 -0.3622 -0.9957 3071530 BCB03_000502 CCOC(=O)[C@H]1C[C@H]2O[C@]32C[C@H]1C(=O)N4CCCC4[C@@H]3O[Si](C)(C)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J04 compound treatment 211680.0 -251000.0 -0.67 236010.0 -176000.0 -0.48 -0.816 -0.9873 2129008 BCB03_000503 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)NCc3ccc(F)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J05 mock treatment 410200.0 -52200.0 -0.14 202200.0 -210000.0 -0.58 -0.5067 -0.8535 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J06 mock treatment 313170.0 -149000.0 -0.4 484270.0 71900.0 0.2 -0.1424 -0.3202 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J07 compound treatment 593760.0 131000.0 0.35 188870.0 -224000.0 -0.61 -0.1859 -0.263 3071528 BCB03_000504 CCOC(=O)[C@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@@H]2O[Si](C)(C)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J08 compound treatment 372960.0 -89500.0 -0.24 296800.0 -116000.0 -0.32 -0.3934 -0.9902 3187877 BCB03_000505 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC(=O)[C@@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J09 compound treatment 283490.0 -179000.0 -0.48 694450.0 282000.0 0.77 0.2096 0.2303 3071529 BCB03_000506 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J10 compound treatment 433930.0 -28500.0 -0.08 498030.0 85600.0 0.24 0.1124 0.4548 3188005 BCB03_000507 CC(C)C[C@@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J11 compound treatment 506880.0 44400.0 0.12 337120.0 -75300.0 -0.21 -0.0622 -0.261 3071527 BCB03_000508 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J12 compound treatment 422560.0 -39900.0 -0.11 340480.0 -71900.0 -0.2 -0.215 -0.958 3188007 BCB03_000509 CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J13 compound treatment 173460.0 -289000.0 -0.77 507800.0 95400.0 0.26 -0.3606 -0.4424 3071654 BCB03_000510 [O-][N+](=O)c1ccccc1S(=O)(=O)N2CCC[C@@H]2[C@H]3OCC=C3C(=C)C=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J14 compound treatment 516240.0 53800.0 0.14 598950.0 187000.0 0.51 0.4637 0.8719 3188008 BCB03_000511 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CC\C=C\CNC(=O)[C@@H]5CCCN5C(=O)[C@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J15 compound treatment 182510.0 -280000.0 -0.75 111450.0 -301000.0 -0.83 -1.1129 -0.9988 3071597 BCB03_000512 Cc1ccc(cc1)S(=O)(=O)NC/C=C\C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J16 compound treatment 609650.0 147000.0 0.39 433560.0 21100.0 0.06 0.3191 0.8028 3188142 BCB03_000513 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J17 compound treatment 491400.0 29000.0 0.08 351490.0 -60900.0 -0.17 -0.0636 -0.3449 3071598 BCB03_000514 Cc1ccc(cc1)S(=O)(=O)NC/C=C/C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J18 compound treatment 523370.0 60900.0 0.16 406490.0 -5920.0 -0.02 0.1036 0.6333 3188271 BCB03_000515 CC(C)C[C@H]1NC(=O)CNC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J19 compound treatment 245660.0 -217000.0 -0.58 167520.0 -245000.0 -0.67 -0.8848 -0.9972 3188138 BCB03_000516 Cc1ccc(cc1)S(=O)(=O)N(CCC=C)CC#C[C@H]2Oc3ccccc3S(=O)(=O)N4CCC[C@@H]24 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J20 compound treatment 461690.0 -745.0 0.0 480960.0 68500.0 0.19 0.1317 0.6996 3188272 BCB03_000517 CC(C)C[C@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J21 mock treatment 316320.0 -146000.0 -0.39 608260.0 196000.0 0.54 0.1042 0.1569 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J22 mock treatment 426990.0 -35400.0 -0.09 573220.0 161000.0 0.44 0.2452 0.5431 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J23 compound treatment 290370.0 -172000.0 -0.46 300160.0 -112000.0 -0.31 -0.5429 -0.9811 3071656 BCB03_000518 CN1C(=C)C2CC3C4C(C5CO[C@H]([C@H]6CCCN6S(=O)(=O)c7ccccc7[N+](=O)[O-])C5=C3CC2C1=O)C(=O)N(C)C4=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 J24 compound treatment 402830.0 -59600.0 -0.16 384740.0 -27700.0 -0.08 -0.1663 -0.9427 3188275 BCB03_000519 CC(C)C[C@H]1NC(=O)[C@H](C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K01 compound treatment 445810.0 -16600.0 -0.04 432410.0 20000.0 0.05 0.0074 0.1051 3071254 BCB03_000520 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccccc2)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K02 compound treatment 722720.0 260000.0 0.7 356430.0 -56000.0 -0.15 0.3829 0.5378 3220747 BCB03_000521 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCCC2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K03 compound treatment 821680.0 359000.0 0.96 217120.0 -195000.0 -0.54 0.2994 0.2724 3189418 BCB03_000522 CC#CCO[Si](C#Cc1ccccc1)(C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K04 compound treatment 363270.0 -99200.0 -0.26 270840.0 -142000.0 -0.39 -0.4621 -0.9825 3220749 BCB03_000523 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCC(C)C)oc(C(=O)Cc2ccccc2)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K05 compound treatment 499520.0 37100.0 0.1 204060.0 -208000.0 -0.57 -0.3344 -0.5761 3071256 BCB03_000524 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccc(Oc3ccccc3)cc2)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K06 compound treatment 275800.0 -187000.0 -0.5 771880.0 359000.0 0.99 0.3453 0.3123 3220751 BCB03_000525 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2ccc(OC)cc2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K07 mock treatment 225180.0 -237000.0 -0.63 352260.0 -60200.0 -0.17 -0.5649 -0.8626 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K08 mock treatment 249360.0 -213000.0 -0.57 351400.0 -61000.0 -0.17 -0.5209 -0.878 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K09 compound treatment 499140.0 36700.0 0.1 342350.0 -70100.0 -0.19 -0.0667 -0.3089 3071257 BCB03_000526 CC[C@@H](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)C#C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K10 compound treatment 203840.0 -259000.0 -0.69 707210.0 295000.0 0.81 0.0839 0.0788 3220772 BCB03_000527 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCc2c[nH]c3ccccc23)oc(C(=O)Cc4ccccc4)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K11 compound treatment 291260.0 -171000.0 -0.46 365760.0 -46700.0 -0.13 -0.4139 -0.8716 3189421 BCB03_000528 CC(C)[Si](Oc1ccccc1Br)(C#CCCCC#N)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K12 compound treatment 550080.0 87600.0 0.23 246010.0 -166000.0 -0.46 -0.1575 -0.3068 3220775 BCB03_000529 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2nc[nH]n2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K13 compound treatment 177700.0 -285000.0 -0.76 475410.0 63000.0 0.17 -0.4155 -0.5327 3189422 BCB03_000530 CC[C@@H](O[Si](C#CCCCC#N)(C(C)C)C(C)C)C#C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K14 compound treatment 628800.0 166000.0 0.44 590990.0 179000.0 0.49 0.6609 0.9988 3220649 BCB03_000531 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K15 mock treatment 334110.0 -128000.0 -0.34 194770.0 -218000.0 -0.6 -0.6649 -0.9652 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K16 mock treatment 467940.0 5510.0 0.01 192130.0 -220000.0 -0.6 -0.4172 -0.6897 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K17 compound treatment 400090.0 -62300.0 -0.17 573540.0 161000.0 0.44 0.195 0.4127 3189552 BCB03_000532 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K18 compound treatment 758880.0 296000.0 0.79 654720.0 242000.0 0.67 1.0303 0.9962 3220651 BCB03_000533 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4cncn4C)oc(C(=O)C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K19 compound treatment 629450.0 167000.0 0.45 422850.0 10400.0 0.03 0.3357 0.751 3189553 BCB03_000534 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K20 compound treatment 423220.0 -39200.0 -0.1 217620.0 -195000.0 -0.53 -0.4522 -0.8298 3220653 BCB03_000535 CCCCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K21 compound treatment 455370.0 -7060.0 -0.02 154400.0 -258000.0 -0.71 -0.5142 -0.7257 3189554 BCB03_000536 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(Cc2cccc(Cl)c2)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K22 compound treatment 322240.0 -140000.0 -0.37 483790.0 71400.0 0.2 -0.1262 -0.2986 3220655 BCB03_000537 CCOC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K23 mock treatment 570610.0 108000.0 0.29 729610.0 317000.0 0.87 0.8201 0.8938 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 K24 mock treatment 501940.0 39500.0 0.11 343420.0 -69000.0 -0.19 -0.0593 -0.2736 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L01 compound treatment 402660.0 -59800.0 -0.16 448560.0 36100.0 0.1 -0.0427 -0.2273 3071655 BCB03_000538 CN1C(=O)C2CC=C(CC2C1=O)C3=CCO[C@@H]3[C@H]4CCCN4S(=O)(=O)c5ccccc5[N+](=O)[O-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L02 compound treatment 244720.0 -218000.0 -0.58 491730.0 79300.0 0.22 -0.2572 -0.4142 3188392 BCB03_000539 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)CNC4=O)[C@@H]6O[C@@]61C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L03 compound treatment 726370.0 264000.0 0.7 375610.0 -36800.0 -0.1 0.427 0.5996 3188141 BCB03_000540 C=CC(=C)[C@H]1Oc2ccccc2S(=O)(=O)N3CCC[C@@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L04 compound treatment 590650.0 128000.0 0.34 241830.0 -171000.0 -0.47 -0.089 -0.1534 3188274 BCB03_000541 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L05 compound treatment 397700.0 -64700.0 -0.17 362240.0 -50200.0 -0.14 -0.2197 -0.9937 3071592 BCB03_000542 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L06 compound treatment 266900.0 -196000.0 -0.52 530610.0 118000.0 0.32 -0.1398 -0.2274 3070931 BCB03_000543 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L07 mock treatment 536750.0 74300.0 0.2 164540.0 -248000.0 -0.68 -0.3408 -0.4808 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L08 mock treatment 790040.0 328000.0 0.88 724830.0 312000.0 0.86 1.2252 1.0 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L09 compound treatment 247840.0 -215000.0 -0.57 757280.0 345000.0 0.95 0.2642 0.2387 3071592 BCB03_000544 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L10 compound treatment 331220.0 -131000.0 -0.35 429540.0 17100.0 0.05 -0.2146 -0.6068 3070933 BCB03_000545 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L11 compound treatment 425880.0 -36600.0 -0.1 241040.0 -171000.0 -0.47 -0.4017 -0.836 3071581 BCB03_000546 O=C1C2CC=C(CC2C(=O)c3ccccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L12 compound treatment 341380.0 -121000.0 -0.32 614490.0 202000.0 0.55 0.1637 0.2549 3188523 BCB03_000547 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L13 compound treatment 701120.0 239000.0 0.64 223200.0 -189000.0 -0.52 0.0835 0.1015 3071582 BCB03_000548 O=C1c2ccccc2C(=O)c3cc(ccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L14 compound treatment 353120.0 -109000.0 -0.29 549030.0 137000.0 0.38 0.0588 0.1236 3188524 BCB03_000549 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L15 mock treatment 197160.0 -265000.0 -0.71 207040.0 -205000.0 -0.56 -0.8997 -0.9936 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L16 mock treatment 555950.0 93500.0 0.25 416480.0 4070.0 0.01 0.1845 0.738 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L17 compound treatment 348360.0 -114000.0 -0.3 331770.0 -80600.0 -0.22 -0.372 -0.9877 3071529 BCB03_000550 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L18 compound treatment 524380.0 61900.0 0.17 354370.0 -58000.0 -0.16 0.0043 0.0188 3188525 BCB03_000551 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L19 compound treatment 766400.0 304000.0 0.81 383960.0 -28500.0 -0.08 0.5189 0.6361 3071527 BCB03_000552 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L20 compound treatment 410730.0 -51700.0 -0.14 429930.0 17500.0 0.05 -0.0636 -0.4352 3188526 BCB03_000553 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@@H](CCc6ccccc6)O1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L21 compound treatment 272980.0 -189000.0 -0.51 302470.0 -110000.0 -0.3 -0.5713 -0.9695 3071531 BCB03_000554 CCOC(=O)[C@@H]1[C@@H]2CN(CCC2=C[C@@H]3[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]4CCCN4C(=O)[C@@H]13)S(=O)(=O)c5ccc(C)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L22 compound treatment 534240.0 71800.0 0.19 448200.0 35800.0 0.1 0.2051 0.9517 3188538 BCB03_000555 CCCC[C@H]1OB(O)C[C@H]2C1=C(C)Cn3n2c(=O)n(c4ccccc4)c3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L23 mock treatment 607040.0 145000.0 0.39 685070.0 273000.0 0.75 0.8024 0.9526 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 L24 mock treatment 595580.0 133000.0 0.36 269510.0 -143000.0 -0.39 -0.026 -0.049 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M01 compound treatment 794750.0 332000.0 0.89 412480.0 67.3 0.0 0.6278 0.7073 3071269 BCB03_000556 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](C)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M02 compound treatment 627040.0 165000.0 0.44 428070.0 15700.0 0.04 0.3413 0.7726 3220657 BCB03_000557 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)c3ccccn3)oc(C(=O)C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M03 compound treatment 261050.0 -201000.0 -0.54 363110.0 -49300.0 -0.14 -0.4761 -0.8583 3189557 BCB03_000558 CCCC#C[Si](O[C@H](CC)c1cn(Cc2ccccc2)nn1)(C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M04 compound treatment 499040.0 36600.0 0.1 619840.0 207000.0 0.57 0.4718 0.8166 3220659 BCB03_000559 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCCC3)oc(C(=O)C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M05 compound treatment 506310.0 43900.0 0.12 296230.0 -116000.0 -0.32 -0.1427 -0.4199 3071329 BCB03_000560 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M06 compound treatment 610880.0 148000.0 0.4 645120.0 233000.0 0.64 0.7321 0.9737 3220661 BCB03_000561 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M07 compound treatment 304290.0 -158000.0 -0.42 389220.0 -23200.0 -0.06 -0.3437 -0.8046 3071331 BCB03_000562 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](C)c2ccccc2)(C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M08 compound treatment 530840.0 68400.0 0.18 406270.0 -6140.0 -0.02 0.1173 0.6391 3220665 BCB03_000563 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(Cc3ccccc3)nn2)C(C)C)oc(C(=O)C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M09 mock treatment 459520.0 -2910.0 -0.01 284840.0 -128000.0 -0.35 -0.2532 -0.7226 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M10 mock treatment 920480.0 458000.0 1.22 455960.0 43500.0 0.12 0.9496 0.7725 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M11 compound treatment 410430.0 -52000.0 -0.14 272340.0 -140000.0 -0.38 -0.3701 -0.9053 3071332 BCB03_000564 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M12 compound treatment 649880.0 187000.0 0.5 619840.0 207000.0 0.57 0.7567 0.9979 3220667 BCB03_000565 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)C3(O)CCCCC3)C(C)C)oc(C(=O)C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M13 mock treatment 411260.0 -51200.0 -0.14 684360.0 272000.0 0.75 0.4313 0.5682 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M14 mock treatment 750680.0 288000.0 0.77 565190.0 153000.0 0.42 0.841 0.9592 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M15 compound treatment 700020.0 238000.0 0.63 437310.0 24900.0 0.07 0.4971 0.7788 3189692 BCB03_000566 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M16 compound treatment 523160.0 60700.0 0.16 419560.0 7150.0 0.02 0.1286 0.7869 3220669 BCB03_000567 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3cncn3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M17 compound treatment 809790.0 347000.0 0.93 728400.0 316000.0 0.87 1.2695 0.9994 3189693 BCB03_000568 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M18 compound treatment 871810.0 409000.0 1.09 361700.0 -50700.0 -0.14 0.6747 0.6121 3414054 BCB03_000569 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M19 compound treatment 649990.0 188000.0 0.5 379780.0 -32600.0 -0.09 0.2909 0.5716 3189694 BCB03_000570 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M20 compound treatment 489720.0 27300.0 0.07 283120.0 -129000.0 -0.35 -0.1995 -0.5504 3414055 BCB03_000571 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(Cc4ccccc4)nn3)oc(C(=O)C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M21 compound treatment 616120.0 154000.0 0.41 223850.0 -189000.0 -0.52 -0.0758 -0.1147 3071395 BCB03_000572 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M22 compound treatment 646560.0 184000.0 0.49 604890.0 192000.0 0.53 0.7214 0.9994 3414056 BCB03_000573 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M23 compound treatment 305180.0 -157000.0 -0.42 505760.0 93300.0 0.26 -0.1158 -0.2353 3189697 BCB03_000574 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 M24 compound treatment 684390.0 222000.0 0.59 437030.0 24600.0 0.07 0.467 0.7826 3414057 BCB03_000575 CCCCc1cn(C[C@@H]2CCCN2C(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N01 compound treatment 696430.0 234000.0 0.62 440970.0 28600.0 0.08 0.4974 0.7896 3071585 BCB03_000576 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N02 compound treatment 583480.0 121000.0 0.32 825470.0 413000.0 1.13 1.0305 0.8739 3215882 BCB03_000577 CCCC[C@H]1OB(O)C[C@H]2C1=C(COC)Cn3n2c(=O)n(c4ccccc4)c3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N03 compound treatment 276930.0 -186000.0 -0.5 276010.0 -136000.0 -0.37 -0.6152 -0.9905 3188130 BCB03_000578 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N04 compound treatment 430530.0 -31900.0 -0.09 394750.0 -17700.0 -0.05 -0.0945 -0.9643 3215880 BCB03_000579 CCCC[C@H]1OB(O)C[C@H]2C1=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N05 compound treatment 497450.0 35000.0 0.09 298250.0 -114000.0 -0.31 -0.1555 -0.4754 3071587 BCB03_000580 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N06 compound treatment 369440.0 -93000.0 -0.25 434080.0 21700.0 0.06 -0.1336 -0.523 3188542 BCB03_000581 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N07 compound treatment 514040.0 51600.0 0.14 331330.0 -81100.0 -0.22 -0.0599 -0.2289 3071588 BCB03_000582 BrC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N08 compound treatment 236420.0 -226000.0 -0.6 395280.0 -17100.0 -0.05 -0.4601 -0.7599 3071661 BCB03_000583 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N09 mock treatment 361200.0 -101000.0 -0.27 587300.0 175000.0 0.48 0.1483 0.2691 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N10 mock treatment 733920.0 271000.0 0.73 330050.0 -82400.0 -0.23 0.3529 0.4645 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N11 compound treatment 304690.0 -158000.0 -0.42 179580.0 -233000.0 -0.64 -0.7499 -0.9795 3071589 BCB03_000584 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N12 compound treatment 228820.0 -234000.0 -0.62 240850.0 -172000.0 -0.47 -0.7743 -0.9904 3188543 BCB03_000585 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N13 mock treatment 829000.0 367000.0 0.98 517310.0 105000.0 0.29 0.896 0.8779 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N14 mock treatment 842010.0 380000.0 1.01 625070.0 213000.0 0.58 1.1297 0.9656 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N15 compound treatment 305210.0 -157000.0 -0.42 367840.0 -44600.0 -0.12 -0.3835 -0.8767 3071590 BCB03_000586 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N16 compound treatment 244640.0 -218000.0 -0.58 269410.0 -143000.0 -0.39 -0.689 -0.9817 3070948 BCB03_000587 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)C=CC3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N17 compound treatment 275690.0 -187000.0 -0.5 281350.0 -131000.0 -0.36 -0.6071 -0.9872 3071591 BCB03_000588 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N18 compound treatment 185920.0 -277000.0 -0.74 163640.0 -249000.0 -0.68 -1.0052 -0.9992 3070949 BCB03_000589 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)C=CC3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N19 compound treatment 175250.0 -287000.0 -0.77 182590.0 -230000.0 -0.63 -0.9886 -0.9953 3188261 BCB03_000590 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3cccc(C)c3)C(=O)[C@@]42CO4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N20 compound treatment 254880.0 -208000.0 -0.55 147000.0 -265000.0 -0.73 -0.9073 -0.9909 3070950 BCB03_000591 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)C=CC3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N21 compound treatment 286410.0 -176000.0 -0.47 391890.0 -20500.0 -0.06 -0.3723 -0.7862 3071600 BCB03_000592 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(OC)C(=O)[C@@]43CO4)Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N22 compound treatment 295440.0 -167000.0 -0.45 268240.0 -144000.0 -0.4 -0.5953 -0.9982 3070951 BCB03_000593 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)C=CC3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N23 compound treatment 586020.0 124000.0 0.33 612120.0 200000.0 0.55 0.6211 0.9705 3071601 BCB03_000594 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 N24 compound treatment 637480.0 175000.0 0.47 544750.0 132000.0 0.36 0.5875 0.9922 3071664 BCB03_000595 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O01 compound treatment 601720.0 139000.0 0.37 632650.0 220000.0 0.6 0.6906 0.9728 3187592 BCB03_000596 CC(C)[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O02 compound treatment 572960.0 111000.0 0.3 505920.0 93500.0 0.26 0.3903 0.9976 3220705 BCB03_000597 CCc1oc(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCCC3)c(C(=O)OC)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O03 compound treatment 503240.0 40800.0 0.11 594270.0 182000.0 0.5 0.4301 0.8416 3071397 BCB03_000598 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O04 compound treatment 496170.0 33700.0 0.09 257540.0 -155000.0 -0.43 -0.2369 -0.5452 3220708 BCB03_000599 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O05 compound treatment 395650.0 -66800.0 -0.18 326420.0 -86000.0 -0.24 -0.2931 -0.9904 3071398 BCB03_000600 CC(C)[Si](O[C@H](C)c1cn(Cc2ccccc2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O06 compound treatment 674450.0 212000.0 0.57 451360.0 38900.0 0.11 0.476 0.826 3220711 BCB03_000601 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O07 compound treatment 510610.0 48200.0 0.13 359440.0 -53000.0 -0.15 -0.0118 -0.061 3071399 BCB03_000602 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O08 compound treatment 443400.0 -19000.0 -0.05 580010.0 168000.0 0.46 0.2894 0.6252 3220713 BCB03_000603 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4N)oc(C(=O)C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O09 compound treatment 304060.0 -158000.0 -0.42 429400.0 17000.0 0.05 -0.2661 -0.6254 3187596 BCB03_000604 CC(C)[Si](O[C@H](C)c1cn(Cc2cccc(Cl)c2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O10 compound treatment 281060.0 -181000.0 -0.48 632520.0 220000.0 0.6 0.0847 0.1094 3220715 BCB03_000605 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O11 mock treatment 484280.0 21800.0 0.06 523490.0 111000.0 0.3 0.2569 0.8274 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O12 mock treatment 328380.0 -134000.0 -0.36 388220.0 -24200.0 -0.07 -0.3002 -0.8242 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O13 compound treatment 358810.0 -104000.0 -0.28 380410.0 -32000.0 -0.09 -0.2578 -0.8879 3071400 BCB03_000606 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](C)c2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O14 compound treatment 327360.0 -135000.0 -0.36 330560.0 -81900.0 -0.22 -0.414 -0.974 3220717 BCB03_000607 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O15 compound treatment 384600.0 -77800.0 -0.21 474600.0 62200.0 0.17 -0.0263 -0.0977 3070694 BCB03_000608 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O16 compound treatment 419390.0 -43000.0 -0.11 451280.0 38900.0 0.11 -0.0058 -0.0373 3220739 BCB03_000609 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O17 compound treatment 368290.0 -94100.0 -0.25 663380.0 251000.0 0.69 0.3094 0.4218 3070746 BCB03_000610 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O18 compound treatment 630200.0 168000.0 0.45 736040.0 324000.0 0.89 0.9451 0.9498 3220741 BCB03_000611 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCC4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O19 compound treatment 264900.0 -198000.0 -0.53 233600.0 -179000.0 -0.49 -0.7202 -0.9994 3188534 BCB03_000612 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O20 compound treatment 437720.0 -24700.0 -0.07 602940.0 191000.0 0.52 0.3232 0.613 3220743 BCB03_000613 COCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)N4CCOCC4)c(C(=O)OC)c3C(=O)OC)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O21 compound treatment 222140.0 -240000.0 -0.64 310420.0 -102000.0 -0.28 -0.6518 -0.9309 3188535 BCB03_000614 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O22 compound treatment 312390.0 -150000.0 -0.4 447040.0 34600.0 0.1 -0.2162 -0.5248 3188660 BCB03_000615 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O23 compound treatment 293490.0 -169000.0 -0.45 368660.0 -43800.0 -0.12 -0.404 -0.8652 3188536 BCB03_000616 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 O24 compound treatment 557500.0 95100.0 0.25 500920.0 88500.0 0.24 0.3514 0.9998 3188661 BCB03_000617 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P01 compound treatment 270040.0 -192000.0 -0.51 237610.0 -175000.0 -0.48 -0.7027 -0.9994 3071602 BCB03_000618 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P02 compound treatment 280550.0 -182000.0 -0.49 238740.0 -174000.0 -0.48 -0.6807 -1.0 3071666 BCB03_000619 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(Cc4ccccc4)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P03 compound treatment 486980.0 24500.0 0.07 250720.0 -162000.0 -0.44 -0.2675 -0.5962 3071603 BCB03_000620 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P04 compound treatment 314460.0 -148000.0 -0.4 269540.0 -143000.0 -0.39 -0.5568 -1.0 3071711 BCB03_000621 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(Cc4ccccc4)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P05 compound treatment 165280.0 -297000.0 -0.79 360400.0 -52000.0 -0.14 -0.6622 -0.8211 3071604 BCB03_000622 CCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P06 compound treatment 185870.0 -277000.0 -0.74 609300.0 197000.0 0.54 -0.1401 -0.1531 3071776 BCB03_000623 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(Cc5ccccc5)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P07 compound treatment 172740.0 -290000.0 -0.77 345380.0 -67000.0 -0.18 -0.6773 -0.8515 3071651 BCB03_000624 IC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P08 compound treatment 309650.0 -153000.0 -0.41 227960.0 -184000.0 -0.51 -0.6466 -0.9943 3188405 BCB03_000625 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P09 compound treatment 201980.0 -260000.0 -0.7 288890.0 -124000.0 -0.34 -0.7317 -0.9455 3071652 BCB03_000626 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P10 compound treatment 328710.0 -134000.0 -0.36 214370.0 -198000.0 -0.54 -0.637 -0.9792 3070929 BCB03_000627 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(C)C4=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P11 mock treatment 215000.0 -247000.0 -0.66 366760.0 -45700.0 -0.13 -0.5559 -0.8265 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P12 mock treatment 201490.0 -261000.0 -0.7 324640.0 -87800.0 -0.24 -0.6632 -0.8993 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P13 compound treatment 223610.0 -239000.0 -0.64 161440.0 -251000.0 -0.69 -0.9383 -0.9993 3071653 BCB03_000628 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P14 compound treatment 235200.0 -227000.0 -0.61 195570.0 -217000.0 -0.6 -0.8501 -1.0 3188406 BCB03_000629 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)COc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P15 compound treatment 413540.0 -48900.0 -0.13 211940.0 -200000.0 -0.55 -0.4815 -0.8513 3188268 BCB03_000630 CCCCO[C@H]1C[C@H]2C(=C[C@]1(CO)C(=O)[C@@]32CO3)Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P16 compound treatment 218520.0 -244000.0 -0.65 210560.0 -202000.0 -0.55 -0.8525 -0.9968 3070998 BCB03_000631 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P17 compound treatment 160550.0 -302000.0 -0.81 175210.0 -237000.0 -0.65 -1.0306 -0.9944 3071714 BCB03_000632 OC[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P18 compound treatment 189510.0 -273000.0 -0.73 238140.0 -174000.0 -0.48 -0.8538 -0.9791 3188793 BCB03_000633 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P19 compound treatment 209760.0 -253000.0 -0.67 189370.0 -223000.0 -0.61 -0.9102 -0.9988 3071715 BCB03_000634 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P20 compound treatment 283550.0 -179000.0 -0.48 252340.0 -160000.0 -0.44 -0.6486 -0.9991 3071118 BCB03_000635 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P21 compound treatment 230080.0 -232000.0 -0.62 220280.0 -192000.0 -0.53 -0.8118 -0.9967 3071717 BCB03_000636 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P22 compound treatment 232480.0 -230000.0 -0.61 215390.0 -197000.0 -0.54 -0.8168 -0.998 3071120 BCB03_000637 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P23 compound treatment 354080.0 -108000.0 -0.29 176000.0 -236000.0 -0.65 -0.6636 -0.9338 3071720 BCB03_000638 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2282 P24 compound treatment 353990.0 -108000.0 -0.29 218260.0 -194000.0 -0.53 -0.5817 -0.9589 3188808 BCB03_000639 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A01 compound treatment 239430.0 -347000.0 -0.93 812960.0 247000.0 0.68 -0.1756 -0.1529 3188923 BCB03_000640 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A02 compound treatment 391860.0 -194000.0 -0.52 395950.0 -170000.0 -0.47 -0.6972 -0.9986 3563114 BCB03_000641 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)c3ccccc3C=C1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A03 compound treatment 795930.0 210000.0 0.56 595620.0 29700.0 0.08 0.4536 0.8015 3071127 BCB03_000642 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)CCc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A04 compound treatment 455770.0 -131000.0 -0.35 350020.0 -216000.0 -0.59 -0.6657 -0.968 3563115 BCB03_000643 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C)c4ccccc24 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A05 compound treatment 333870.0 -252000.0 -0.67 329610.0 -236000.0 -0.65 -0.9355 -0.9998 3071425 BCB03_000644 CCCC[C@@H](O)C1=C(C)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A06 compound treatment 306560.0 -280000.0 -0.75 367530.0 -198000.0 -0.54 -0.9135 -0.9879 3563116 BCB03_000645 COc1ccc(CN/2C(C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A07 compound treatment 803650.0 217000.0 0.58 267120.0 -299000.0 -0.82 -0.1696 -0.1687 3215868 BCB03_000646 CCCC[C@@H](O)C1=C(COC)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A08 compound treatment 297330.0 -289000.0 -0.77 551090.0 -14900.0 -0.04 -0.5746 -0.7434 3563118 BCB03_000647 COc1ccc(CN2CCc3ccccc3C2C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A09 compound treatment 305920.0 -280000.0 -0.75 330420.0 -236000.0 -0.65 -0.9867 -0.9973 3215866 BCB03_000648 CCCC[C@@H](O)C1=C(COc2ccccc2)Cn3n([C@H]1CO)c(=O)n(c4ccccc4)c3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A10 compound treatment 334510.0 -252000.0 -0.67 550970.0 -15000.0 -0.04 -0.5046 -0.7489 3563119 BCB03_000649 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)c3ccccc3C=C1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A11 compound treatment 304970.0 -281000.0 -0.75 612720.0 46800.0 0.13 -0.4405 -0.5779 3070999 BCB03_000650 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A12 compound treatment 586520.0 238.0 0.0 485010.0 -80900.0 -0.22 -0.1567 -0.7051 3563120 BCB03_000651 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C=C)c4ccccc24 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A13 mock treatment 612800.0 26500.0 0.07 339440.0 -227000.0 -0.62 -0.3896 -0.6225 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A14 mock treatment 452160.0 -134000.0 -0.36 530440.0 -35500.0 -0.1 -0.3222 -0.868 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A15 compound treatment 564990.0 -21300.0 -0.06 321280.0 -245000.0 -0.67 -0.5152 -0.7642 3071000 BCB03_000652 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)CCc3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A16 compound treatment 482090.0 -104000.0 -0.28 602040.0 36100.0 0.1 -0.1267 -0.429 3563121 BCB03_000653 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A17 compound treatment 444410.0 -142000.0 -0.38 302040.0 -264000.0 -0.72 -0.7803 -0.9543 3188676 BCB03_000654 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A18 compound treatment 762150.0 176000.0 0.47 624580.0 58600.0 0.16 0.446 0.8981 3563123 BCB03_000655 COc1ccc(CN2CCc3ccccc3C2C=C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A19 compound treatment 714260.0 128000.0 0.34 363890.0 -202000.0 -0.55 -0.1505 -0.231 3188677 BCB03_000656 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A20 compound treatment 467230.0 -119000.0 -0.32 569770.0 3820.0 0.01 -0.2174 -0.6834 3563124 BCB03_000657 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C3CC3)c4ccccc4C=C1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A21 compound treatment 768370.0 182000.0 0.49 382880.0 -183000.0 -0.5 -0.0115 -0.0164 3188788 BCB03_000658 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(Cc4ccccc4)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A22 compound treatment 729390.0 143000.0 0.38 388400.0 -178000.0 -0.49 -0.0744 -0.1201 3563125 BCB03_000659 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C4CC4)c5ccccc25 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A23 compound treatment 669150.0 82900.0 0.22 521920.0 -44000.0 -0.12 0.071 0.2817 3071005 BCB03_000660 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 A24 compound treatment 764160.0 178000.0 0.48 540250.0 -25700.0 -0.07 0.2861 0.5956 3563121 BCB03_000661 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B01 compound treatment 733140.0 147000.0 0.39 796260.0 230000.0 0.63 0.7245 0.9736 3216005 BCB03_000662 CN1C(=O)[C@@H]2C[C@]/3(C)OC[C@H]([C@@H]2C1=O)\C3=C/c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B02 compound treatment 821600.0 235000.0 0.63 771140.0 205000.0 0.56 0.8428 0.9985 3614372 BCB03_000663 CCCNc1ncnc2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B03 compound treatment 539840.0 -46400.0 -0.12 467470.0 -98500.0 -0.27 -0.2789 -0.9376 3216013 BCB03_000664 CN1C(=O)[C@@H]2C[C@]/3(COc4ccccc4)OC[C@H]([C@@H]2C1=O)\C3=C/c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B04 compound treatment 657600.0 71300.0 0.19 588560.0 22600.0 0.06 0.1786 0.8914 3614373 BCB03_000665 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B05 compound treatment 379960.0 -206000.0 -0.55 720920.0 155000.0 0.43 -0.0888 -0.1276 3614374 BCB03_000666 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCc6cccc(Cl)c6)c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B06 compound treatment 706100.0 120000.0 0.32 618760.0 52800.0 0.14 0.3288 0.9359 3614376 BCB03_000667 CC(C)(C)OC(=O)NCCOCCOCCNC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B07 compound treatment 301780.0 -285000.0 -0.76 445050.0 -121000.0 -0.33 -0.772 -0.931 3614378 BCB03_000668 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCC#C)c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B08 compound treatment 678530.0 92200.0 0.25 709820.0 144000.0 0.39 0.4535 0.9742 3614380 BCB03_000669 Oc1ccc2ncnc(NCc3ccccc3)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B09 compound treatment 789360.0 203000.0 0.54 763320.0 197000.0 0.54 0.7667 1.0 3614381 BCB03_000670 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B10 compound treatment 220110.0 -366000.0 -0.98 203720.0 -362000.0 -0.99 -1.3948 -1.0 3614383 BCB03_000671 ONC(=O)/C=C/c1ccc(OCCc2cccs2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B11 compound treatment 313140.0 -273000.0 -0.73 668170.0 102000.0 0.28 -0.3174 -0.4061 3614385 BCB03_000672 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B12 compound treatment 397930.0 -188000.0 -0.5 346620.0 -219000.0 -0.6 -0.7815 -0.996 3614386 BCB03_000673 ONC(=O)/C=C/c1ccc(OCc2ccc-3c(Cc4ccccc43)c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B13 mock treatment 307650.0 -279000.0 -0.74 536970.0 -29000.0 -0.08 -0.5825 -0.7783 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B14 mock treatment 377960.0 -208000.0 -0.56 725390.0 159000.0 0.44 -0.0839 -0.1185 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B15 compound treatment 470400.0 -116000.0 -0.31 287880.0 -278000.0 -0.76 -0.7587 -0.921 3614388 BCB03_000674 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B16 compound treatment 215080.0 -371000.0 -0.99 236480.0 -329000.0 -0.9 -1.3407 -0.999 3614389 BCB03_000675 ONC(=O)/C=C/c1ccc(OCc2ccccc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B17 compound treatment 270820.0 -315000.0 -0.84 216670.0 -349000.0 -0.96 -1.2739 -0.9979 3614391 BCB03_000676 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B18 compound treatment 216760.0 -370000.0 -0.99 201800.0 -364000.0 -1.0 -1.4048 -1.0 3614392 BCB03_000677 ONC(=O)/C=C/c1ccc(OCc2ccc(Cl)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B19 compound treatment 820000.0 234000.0 0.62 625920.0 60000.0 0.16 0.5578 0.8641 3556401 BCB03_000678 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B20 compound treatment 271280.0 -315000.0 -0.84 221120.0 -345000.0 -0.95 -1.2644 -0.9983 3614394 BCB03_000679 Nc1cccc(COc2ccc(/C=C/C(=O)NO)cc2)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B21 compound treatment 786040.0 200000.0 0.53 578820.0 12900.0 0.04 0.4023 0.7523 3556405 BCB03_000680 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B22 compound treatment 244090.0 -342000.0 -0.91 221800.0 -344000.0 -0.94 -1.3144 -0.9999 3614396 BCB03_000681 ONC(=O)/C=C/c1ccc(OCCCc2ccccc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B23 compound treatment 392870.0 -193000.0 -0.52 785040.0 219000.0 0.6 0.06 0.0757 3556409 BCB03_000682 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 B24 compound treatment 217230.0 -369000.0 -0.99 139910.0 -426000.0 -1.17 -1.5241 -0.9964 3614398 BCB03_000683 ONC(=O)/C=C/c1ccc(OCCCCc2ccccc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C01 compound treatment 746350.0 160000.0 0.43 710490.0 145000.0 0.4 0.5829 0.9993 3188790 BCB03_000684 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C02 compound treatment 554610.0 -31700.0 -0.08 705870.0 140000.0 0.38 0.2118 0.5385 3563126 BCB03_000685 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)C=C(C)C=C1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C03 compound treatment 752770.0 166000.0 0.44 623690.0 57700.0 0.16 0.4265 0.9035 3188791 BCB03_000686 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C04 compound treatment 596860.0 10600.0 0.03 219130.0 -347000.0 -0.95 -0.6533 -0.6858 3563127 BCB03_000687 COc1ccc(CN/2C(C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C05 compound treatment 463410.0 -123000.0 -0.33 518500.0 -47400.0 -0.13 -0.3242 -0.9181 3071437 BCB03_000688 OB1OC(CCc2ccccc2)CC=C1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C06 compound treatment 708860.0 123000.0 0.33 742930.0 177000.0 0.49 0.5751 0.9815 3563129 BCB03_000689 COc1ccc(CN2C(C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C07 compound treatment 702410.0 116000.0 0.31 661080.0 95100.0 0.26 0.404 0.9963 3071483 BCB03_000690 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)c2ccncc2)c3ccccc3)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C08 compound treatment 731590.0 145000.0 0.39 719200.0 153000.0 0.42 0.5719 0.9992 3563130 BCB03_000691 COc1ccc(CN2CCC(=CC2C)C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C09 compound treatment 718660.0 132000.0 0.35 634400.0 68500.0 0.19 0.3829 0.9563 3071486 BCB03_000692 CC(=O)OC(C/C=C\B1OC(C)(C)C(C)(C)O1)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C10 compound treatment 619370.0 33100.0 0.09 325800.0 -240000.0 -0.66 -0.4037 -0.6069 3563131 BCB03_000693 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)C=C(C)C=C1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C11 mock treatment 665350.0 79100.0 0.21 434930.0 -131000.0 -0.36 -0.105 -0.2518 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C12 mock treatment 589010.0 2730.0 0.01 613390.0 47400.0 0.13 0.0973 0.7455 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C13 compound treatment 13390.0 -573000.0 -1.53 13780.0 -552000.0 -1.52 -2.1539 -1.0 3188011 BCB03_000694 O=C1C=C(C(=O)c2ccc(cc12)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C14 compound treatment 573140.0 -13100.0 -0.04 301120.0 -265000.0 -0.73 -0.5389 -0.7404 3563132 BCB03_000695 COc1ccc(CN/2C(C=C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C15 mock treatment 678080.0 91800.0 0.25 445760.0 -120000.0 -0.33 -0.0599 -0.1458 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C16 mock treatment 707290.0 121000.0 0.32 358520.0 -207000.0 -0.57 -0.1741 -0.2659 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C17 compound treatment 32500.0 -554000.0 -1.48 17560.0 -548000.0 -1.51 -2.1105 -1.0 3071579 BCB03_000696 O=C1C=C(C(=O)C2=C1CC(=CC2)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C18 compound treatment 309610.0 -277000.0 -0.74 333290.0 -233000.0 -0.64 -0.9742 -0.9974 3563134 BCB03_000697 COc1ccc(CN2C(C=C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C19 compound treatment 223200.0 -363000.0 -0.97 149060.0 -417000.0 -1.14 -1.495 -0.9966 3070932 BCB03_000698 OCC(NC(=O)OCC1c2ccccc2-c3ccccc13)C=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C20 compound treatment 603210.0 16900.0 0.05 377170.0 -189000.0 -0.52 -0.3345 -0.643 3563135 BCB03_000699 COc1ccc(CN2CCC(=CC2C=C)C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C21 compound treatment 612800.0 26500.0 0.07 152000.0 -414000.0 -1.14 -0.7535 -0.6618 3188522 BCB03_000700 COc1ccc(CN([C@H](COC(=O)OC(C)(C)C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C22 compound treatment 687630.0 101000.0 0.27 286660.0 -279000.0 -0.77 -0.3508 -0.4314 1025568 BCB03_000701 COc1cc2CCN(C)C(C)c2cc1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C23 compound treatment 492190.0 -94100.0 -0.25 616180.0 50200.0 0.14 -0.0802 -0.2797 3070934 BCB03_000702 CC(=O)OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 C24 compound treatment 633630.0 47300.0 0.13 505240.0 -60700.0 -0.17 -0.0284 -0.1359 3563136 BCB03_000703 COc1cc2CCN(C)C(C=C)c2cc1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D01 compound treatment 834310.0 248000.0 0.66 728910.0 163000.0 0.45 0.7848 0.9817 3556407 BCB03_000704 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D02 compound treatment 140850.0 -445000.0 -1.19 142850.0 -423000.0 -1.16 -1.6626 -0.9999 3614403 BCB03_000705 ONC(=O)/C=C/c1ccc(OCCn2c3ccccc3c4ccccc24)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D03 compound treatment 748530.0 162000.0 0.43 723230.0 157000.0 0.43 0.6118 1.0 3556412 BCB03_000706 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D04 compound treatment 718610.0 132000.0 0.35 610360.0 44400.0 0.12 0.3361 0.899 3614405 BCB03_000707 Cc1cccc(Cl)c1NC(=O)C2=CC=C(Cl)C2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D05 compound treatment 722090.0 136000.0 0.36 678470.0 113000.0 0.31 0.4749 0.9968 3614406 BCB03_000708 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D06 compound treatment 171690.0 -415000.0 -1.11 147600.0 -418000.0 -1.15 -1.5952 -0.9998 3614408 BCB03_000709 COc1ccc(CN(C(=O)C2=CC=C(Cl)C2)c3c(C)cccc3Cl)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D07 compound treatment 617450.0 31200.0 0.08 571680.0 5730.0 0.02 0.07 0.8262 3614409 BCB03_000710 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D08 compound treatment 346020.0 -240000.0 -0.64 449340.0 -117000.0 -0.32 -0.6801 -0.9484 3614410 BCB03_000711 COc1ccc(CN(C(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3)c4c(C)cccc4Cl)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D09 compound treatment 779750.0 193000.0 0.52 397660.0 -168000.0 -0.46 0.0387 0.0558 3614411 BCB03_000712 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D10 compound treatment 420690.0 -166000.0 -0.44 418900.0 -147000.0 -0.4 -0.5982 -0.999 3614412 BCB03_000713 Cc1cccc(Cl)c1NC(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D11 mock treatment 755850.0 170000.0 0.45 572430.0 6480.0 0.02 0.3328 0.7343 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D12 mock treatment 715910.0 130000.0 0.35 308980.0 -257000.0 -0.71 -0.254 -0.3232 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D13 compound treatment 725840.0 140000.0 0.37 687290.0 121000.0 0.33 0.4991 0.9984 3614413 BCB03_000714 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D14 compound treatment 162190.0 -424000.0 -1.13 282290.0 -284000.0 -0.78 -1.3516 -0.9833 3614414 BCB03_000715 Cc1cccc(Cl)c1NC(=O)c2cnc(Nc3cc(nc(C)n3)N4CCN(CCO)CC4)s2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D15 mock treatment 675040.0 88800.0 0.24 518630.0 -47300.0 -0.13 0.0758 0.2803 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D16 mock treatment 660220.0 73900.0 0.2 718940.0 153000.0 0.42 0.4367 0.9408 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D17 compound treatment 394560.0 -192000.0 -0.51 277510.0 -288000.0 -0.79 -0.922 -0.9777 3556423 BCB03_000716 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D18 compound treatment 443900.0 -142000.0 -0.38 306780.0 -259000.0 -0.71 -0.772 -0.9569 3614415 BCB03_000717 COC(=O)C1(CCCC1)C2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)CCO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D19 compound treatment 730330.0 144000.0 0.38 551870.0 -14100.0 -0.04 0.2447 0.6329 3556419 BCB03_000718 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D20 compound treatment 615970.0 29700.0 0.08 435640.0 -130000.0 -0.36 -0.1969 -0.5373 3614418 BCB03_000719 Cn1c(=O)n2[C@H]3[C@@H]4[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc5ccccc5)N4CC3=C[C@@H](C6CC6)n2c1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D21 compound treatment 628910.0 42600.0 0.11 449240.0 -117000.0 -0.32 -0.1461 -0.4295 3614420 BCB03_000720 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D22 compound treatment 418020.0 -168000.0 -0.45 277060.0 -289000.0 -0.79 -0.8786 -0.9638 3614421 BCB03_000721 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CCCC=C[C@H]4[C@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D23 compound treatment 277310.0 -309000.0 -0.83 317410.0 -249000.0 -0.68 -1.066 -0.9955 3614424 BCB03_000722 COC(=O)c1cn(CC(=O)N2CCC3(CC2)N(CNC3=O)c4ccccc4)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 D24 compound treatment 38420.0 -548000.0 -1.46 23520.0 -542000.0 -1.49 -2.0877 -1.0 3614425 BCB03_000723 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E01 mock treatment 826820.0 241000.0 0.64 721550.0 156000.0 0.43 0.7564 0.9803 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E02 mock treatment 565970.0 -20300.0 -0.05 792930.0 227000.0 0.62 0.4023 0.6431 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E03 compound treatment 743200.0 157000.0 0.42 504990.0 -61000.0 -0.17 0.178 0.3945 3070935 BCB03_000724 O=C(CCCCCCC(=O)Nc1ccccc1)N/N=C/c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E04 compound treatment 817840.0 232000.0 0.62 796420.0 230000.0 0.63 0.8848 0.9999 3563137 BCB03_000725 COc1cc2CCN(C)C(C3CC3)c2cc1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E05 compound treatment 761960.0 176000.0 0.47 776580.0 211000.0 0.58 0.7407 0.9946 3070936 BCB03_000726 C/C(=N\O)/C(=O)NCCCCCNC(=O)OCc1ccccc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E06 compound treatment 809620.0 223000.0 0.6 631710.0 65800.0 0.18 0.5495 0.8816 3563138 BCB03_000727 COCC#CC1N(C)CCc2cc(OC)c(OC)cc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E07 compound treatment 643620.0 57300.0 0.15 638910.0 73000.0 0.2 0.2499 0.9912 3070944 BCB03_000728 O/N=C(\Cc1ccccc1)/C(=O)NCCCCCNC(=O)OCc2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E08 compound treatment 817220.0 231000.0 0.62 720220.0 154000.0 0.42 0.7357 0.9832 3562035 BCB03_000729 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E09 mock treatment 765120.0 179000.0 0.48 825080.0 259000.0 0.71 0.8408 0.9812 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E10 mock treatment 497520.0 -88800.0 -0.24 724090.0 158000.0 0.43 0.1394 0.2817 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E11 compound treatment 647240.0 61000.0 0.16 678280.0 112000.0 0.31 0.3332 0.9554 3188539 BCB03_000730 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccccc4)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E12 compound treatment 325920.0 -260000.0 -0.7 265450.0 -300000.0 -0.82 -1.0751 -0.9964 3563139 BCB03_000731 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E13 compound treatment 621730.0 35400.0 0.09 593280.0 27300.0 0.08 0.12 0.9934 3188540 BCB03_000732 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccccc4)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E14 compound treatment 296070.0 -290000.0 -0.78 250760.0 -315000.0 -0.87 -1.16 -0.9985 3563140 BCB03_000733 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C=C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E15 compound treatment 788550.0 202000.0 0.54 495360.0 -70600.0 -0.19 0.245 0.4268 3188541 BCB03_000734 C[C@@H]1ON([C@@H]([C@H]1C(=O)O)c2ccccc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E16 compound treatment 221610.0 -365000.0 -0.97 245440.0 -321000.0 -0.88 -1.3109 -0.9987 3563141 BCB03_000735 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C4CC4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E17 mock treatment 710850.0 125000.0 0.33 713200.0 147000.0 0.4 0.5211 0.9953 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E18 mock treatment 759850.0 174000.0 0.46 200580.0 -365000.0 -1.0 -0.3815 -0.3452 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E19 compound treatment 536450.0 -49800.0 -0.13 666630.0 101000.0 0.28 0.1013 0.3303 3070947 BCB03_000736 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E20 compound treatment 384160.0 -202000.0 -0.54 343060.0 -223000.0 -0.61 -0.8144 -0.998 3563142 BCB03_000737 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E21 compound treatment 294560.0 -292000.0 -0.78 229240.0 -337000.0 -0.92 -1.2046 -0.9964 3188544 BCB03_000738 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E22 compound treatment 738180.0 152000.0 0.41 663130.0 97200.0 0.27 0.4755 0.9793 3563143 BCB03_000739 COc1cc2CCN(C)C(C)(C)c2cc1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E23 compound treatment 430750.0 -156000.0 -0.42 520710.0 -45200.0 -0.12 -0.3816 -0.88 3188657 BCB03_000740 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5cccc(c5)C(=O)OC(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 E24 compound treatment 517200.0 -69100.0 -0.18 498490.0 -67500.0 -0.19 -0.2614 -1.0 3563144 BCB03_000741 COc1cc2CCN(C)C(C)(C=C)c2cc1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F01 mock treatment 847210.0 261000.0 0.7 857570.0 292000.0 0.8 1.0589 0.9976 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F02 mock treatment 464160.0 -122000.0 -0.33 936080.0 370000.0 1.02 0.4879 0.4572 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F03 compound treatment 394520.0 -192000.0 -0.51 307840.0 -258000.0 -0.71 -0.8632 -0.9873 3614432 BCB03_000742 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F04 compound treatment 762400.0 176000.0 0.47 742080.0 176000.0 0.48 0.6746 0.9999 3614434 BCB03_000743 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)CCN=[N+]=[N-] 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F05 compound treatment 828050.0 242000.0 0.65 757290.0 191000.0 0.53 0.8281 0.9948 3614437 BCB03_000744 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)c3ccccc3)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F06 compound treatment 487630.0 -98700.0 -0.26 788720.0 223000.0 0.61 0.2461 0.3696 3614440 BCB03_000745 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N(CC#C)[C@@H]1/C=C/C3CC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F07 compound treatment 534960.0 -51300.0 -0.14 217050.0 -349000.0 -0.96 -0.7742 -0.8001 3614442 BCB03_000746 COC(=O)c1cn(CCCNC(=S)Nc2ccc(cc2)[N+](=O)[O-])nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F08 compound treatment 497010.0 -89300.0 -0.24 386040.0 -180000.0 -0.49 -0.5179 -0.9442 3614443 BCB03_000747 C=C/C=C/[C@H]1[C@@H]2[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc3ccccc3)N2CC1=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F09 mock treatment 649940.0 63700.0 0.17 762820.0 197000.0 0.54 0.5024 0.8867 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F10 mock treatment 614410.0 28100.0 0.08 768390.0 202000.0 0.56 0.4461 0.7955 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F11 compound treatment 787730.0 201000.0 0.54 384340.0 -182000.0 -0.5 0.0279 0.0381 3614446 BCB03_000748 COC(=O)c1cn(CCCNC(=O)Nc2ccccc2)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F12 compound treatment 189320.0 -397000.0 -1.06 245140.0 -321000.0 -0.88 -1.3725 -0.9957 3614447 BCB03_000749 COC(=O)[C@H](Cc1ccccc1)N2C[C@](C)(OC(C)C)O[C@@H](CCN=[N+]=[N-])[C@H]2/C=C/C3CC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F13 compound treatment 756880.0 171000.0 0.46 782020.0 216000.0 0.59 0.7417 0.9915 3614451 BCB03_000750 COC(=O)c1cn(CCNC(=O)Nc2ccccc2)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F14 compound treatment 302080.0 -284000.0 -0.76 279420.0 -287000.0 -0.79 -1.093 -0.9998 3614452 BCB03_000751 COC(=O)C1(CCCC1)C2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)CCO)c(=O)n(C)c5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F15 compound treatment 520770.0 -65500.0 -0.17 513120.0 -52800.0 -0.15 -0.2263 -0.9956 3614455 BCB03_000752 COC(=O)c1cn(CCCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F16 compound treatment 171210.0 -415000.0 -1.11 212870.0 -353000.0 -0.97 -1.4694 -0.9978 3614458 BCB03_000753 OCC[C@@H]1OC(=O)C2(CCCC2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F17 mock treatment 604710.0 18400.0 0.05 713510.0 148000.0 0.41 0.3213 0.7872 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F18 mock treatment 787230.0 201000.0 0.54 719380.0 153000.0 0.42 0.6774 0.9928 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F19 compound treatment 285920.0 -300000.0 -0.8 452800.0 -113000.0 -0.31 -0.7869 -0.9147 3614462 BCB03_000754 COC(=O)c1cn(CCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F20 compound treatment 696280.0 110000.0 0.29 548070.0 -17900.0 -0.05 0.173 0.5809 3563105 BCB03_000755 COC(=O)C1=CN(C)C(C=C)c2ccccc2C=C1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F21 compound treatment 316490.0 -270000.0 -0.72 754890.0 189000.0 0.52 -0.1428 -0.1608 3614464 BCB03_000756 COC(=O)c1cn(CCNC(=O)[C@@H](NS(=O)(=O)c2ccc(C)cc2)C(C)C)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F22 compound treatment 764060.0 178000.0 0.47 230610.0 -335000.0 -0.92 -0.3152 -0.3043 3563108 BCB03_000757 COC(=O)C1=CN(C)C(C2CC2)c3ccccc3C=C1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F23 compound treatment 668320.0 82000.0 0.22 628000.0 62100.0 0.17 0.2754 0.9923 3614467 BCB03_000758 COC(=O)c1cn(C[C@@H]2CCCN2S(=O)(=O)c3ccc(C)cc3)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 F24 compound treatment 734240.0 148000.0 0.4 254760.0 -311000.0 -0.85 -0.3247 -0.3449 3188926 BCB03_000759 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(nc5)C(F)(F)F)C(C)(C)C4CC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G01 compound treatment 701660.0 115000.0 0.31 887230.0 321000.0 0.88 0.8416 0.9008 3188658 BCB03_000760 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G02 compound treatment 493440.0 -92800.0 -0.25 799140.0 233000.0 0.64 0.2774 0.404 3563145 BCB03_000761 COCC#CC1(C)N(C)CCc2cc(OC)c(OC)cc21 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G03 mock treatment 498670.0 -87600.0 -0.23 808510.0 243000.0 0.67 0.3054 0.4327 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G04 mock treatment 403230.0 -183000.0 -0.49 842830.0 277000.0 0.76 0.1918 0.2122 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G05 compound treatment 568850.0 -17400.0 -0.05 699570.0 134000.0 0.37 0.2265 0.6124 3188659 BCB03_000762 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4cccc(NC(=O)OCC5c6ccccc6-c7ccccc57)c4)c8ccc(I)cc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G06 compound treatment 449470.0 -137000.0 -0.37 261510.0 -304000.0 -0.84 -0.8494 -0.9312 3563146 BCB03_000763 COc1ccc(C[N+]2=C(C)c3cc(OC)c(OC)cc3CC2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G07 compound treatment 486650.0 -99600.0 -0.27 326160.0 -240000.0 -0.66 -0.6537 -0.9206 3188672 BCB03_000764 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(OC(=O)OC(C)(C)C)cc4)c5ccc(I)cc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G08 compound treatment 678720.0 92400.0 0.25 269990.0 -296000.0 -0.81 -0.4 -0.471 3563147 BCB03_000765 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G09 compound treatment 473440.0 -113000.0 -0.3 334560.0 -231000.0 -0.64 -0.6623 -0.942 3188673 BCB03_000766 COC(=O)CCCCCCC(=O)Nc1ccc(NC(=O)CCCC[P+](c2ccccc2)(c3ccccc3)c4ccccc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G10 compound treatment 413510.0 -173000.0 -0.46 549700.0 -16200.0 -0.04 -0.3579 -0.7719 3563148 BCB03_000767 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C=C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G11 compound treatment 637790.0 51500.0 0.14 666640.0 101000.0 0.28 0.2928 0.9481 3188674 BCB03_000768 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H]2[C@@H](C)ON([C@@H]2c3ccccc3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G12 compound treatment 252070.0 -334000.0 -0.89 249710.0 -316000.0 -0.87 -1.2451 -0.9999 3563149 BCB03_000769 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C4CC4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G13 compound treatment 595520.0 9240.0 0.02 419540.0 -146000.0 -0.4 -0.2668 -0.6625 3188675 BCB03_000770 CC(C)[C@@H](CO)NC(=O)[C@@H]1[C@@H](C)ON([C@@H]1c2ccccc2)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G14 compound treatment 420800.0 -165000.0 -0.44 508760.0 -57200.0 -0.16 -0.4236 -0.903 3563150 BCB03_000771 COCC#CC1(C)N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc31 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G15 compound treatment 599300.0 13000.0 0.03 732510.0 167000.0 0.46 0.3479 0.7587 3071001 BCB03_000772 COC(=O)[C@@H]1N[C@H]2[C@@H](COc3ccccc23)[C@@H]1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G16 compound treatment 223250.0 -363000.0 -0.97 705680.0 140000.0 0.38 -0.4144 -0.3974 3563151 BCB03_000773 COc1cc2CC(C)N(C)C(C)c2cc1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G17 compound treatment 508340.0 -77900.0 -0.21 236320.0 -330000.0 -0.9 -0.7871 -0.8476 3071002 BCB03_000774 OCC1CC(=NO1)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G18 compound treatment 346090.0 -240000.0 -0.64 255160.0 -311000.0 -0.85 -1.057 -0.9901 3563152 BCB03_000775 COc1cc2CC(C)N(C)C(C=C)c2cc1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G19 mock treatment 830110.0 244000.0 0.65 589440.0 23500.0 0.06 0.5061 0.7734 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G20 mock treatment 611000.0 24700.0 0.07 620070.0 54100.0 0.15 0.1518 0.9333 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G21 compound treatment 320550.0 -266000.0 -0.71 174790.0 -391000.0 -1.07 -1.2612 -0.9798 3071004 BCB03_000776 O[C@H](C=C)[C@H]1CC(=NO1)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G22 compound treatment 714800.0 129000.0 0.34 639100.0 73200.0 0.2 0.3847 0.9674 3563153 BCB03_000777 COc1cc2CC(C)N(C)C(C3CC3)c2cc1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G23 compound treatment 704600.0 118000.0 0.32 287640.0 -278000.0 -0.76 -0.3168 -0.3832 3414065 BCB03_000778 O[C@@H]([C@H]1CC(=NO1)c2ccccc2)[C@@H]3CC(=NO3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 G24 compound treatment 761000.0 175000.0 0.47 650560.0 84600.0 0.23 0.4942 0.9481 3563154 BCB03_000779 COCC#CC1N(C)C(C)Cc2cc(OC)c(OC)cc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H01 compound treatment 664360.0 78100.0 0.21 542790.0 -23200.0 -0.06 0.1025 0.4702 3614478 BCB03_000780 COC(=O)c1cn(CC(=O)N2CCN(C)CC2)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H02 compound treatment 351270.0 -235000.0 -0.63 515400.0 -50500.0 -0.14 -0.542 -0.8431 3061928 BCB03_000781 COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H03 mock treatment 699720.0 113000.0 0.3 815840.0 250000.0 0.69 0.6994 0.9325 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H04 mock treatment 592960.0 6680.0 0.02 838240.0 272000.0 0.75 0.5412 0.7238 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H05 compound treatment 269190.0 -317000.0 -0.85 730240.0 164000.0 0.45 -0.2799 -0.2917 3614479 BCB03_000782 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)Cn2cc(nn2)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H06 compound treatment 238620.0 -348000.0 -0.93 197880.0 -368000.0 -1.01 -1.3712 -0.9991 3614483 BCB03_000783 COCCOc1cc2ncnc(Nc3cccc(C#C)c3)c2cc1OCCOC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H07 compound treatment 248960.0 -337000.0 -0.9 310770.0 -255000.0 -0.7 -1.1325 -0.9923 3614485 BCB03_000784 COC(=O)[C@@H](NC(=O)Cn1cc(nn1)C(=O)OC)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H08 mock treatment 619840.0 33600.0 0.09 249350.0 -317000.0 -0.87 -0.5512 -0.6308 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H09 compound treatment 296490.0 -290000.0 -0.77 666420.0 100000.0 0.28 -0.3523 -0.4287 3614488 BCB03_000785 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(nn3)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H10 mock treatment 414850.0 -171000.0 -0.46 290880.0 -275000.0 -0.76 -0.8578 -0.9713 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H11 compound treatment 408120.0 -178000.0 -0.48 490750.0 -75200.0 -0.21 -0.4825 -0.9301 3614492 BCB03_000786 COC(=O)c1cn(nn1)c2cccc(N)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H12 mock treatment 215390.0 -371000.0 -0.99 819370.0 253000.0 0.7 -0.2085 -0.1723 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H13 compound treatment 666580.0 80300.0 0.21 573830.0 7880.0 0.02 0.167 0.7745 3614494 BCB03_000787 COC(=O)c1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H14 mock treatment 259310.0 -327000.0 -0.87 655100.0 89200.0 0.24 -0.4445 -0.4901 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H15 compound treatment 290480.0 -296000.0 -0.79 203220.0 -363000.0 -1.0 -1.2628 -0.9934 3614495 BCB03_000788 COC(=O)c1cn(CC(=O)N2CCOCC2)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H16 mock treatment 630040.0 43800.0 0.12 785960.0 220000.0 0.6 0.5098 0.8286 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H17 compound treatment 778050.0 192000.0 0.51 405170.0 -161000.0 -0.44 0.0501 0.074 3614498 BCB03_000789 COC(=O)c1cn(CC(=O)Nc2ccc(OC)c(OC)c2)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H18 mock treatment 869930.0 284000.0 0.76 327890.0 -238000.0 -0.65 0.0736 0.0735 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H19 mock treatment 418510.0 -168000.0 -0.45 742160.0 176000.0 0.48 0.0252 0.0382 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H20 mock treatment 358320.0 -228000.0 -0.61 240110.0 -326000.0 -0.89 -1.0631 -0.9824 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H21 compound treatment 506910.0 -79400.0 -0.21 388020.0 -178000.0 -0.49 -0.4953 -0.9302 3614499 BCB03_000790 COC(=O)c1cn(CC(=O)Nc2cc(OC)ccc2OC)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H22 mock treatment 295410.0 -291000.0 -0.78 209280.0 -357000.0 -0.98 -1.2418 -0.9934 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H23 compound treatment 768000.0 182000.0 0.49 799300.0 233000.0 0.64 0.7962 0.9906 3614501 BCB03_000791 COC(=O)c1cn(CC(=O)Nc2nccs2)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 H24 mock treatment 680890.0 94600.0 0.25 348490.0 -217000.0 -0.6 -0.2435 -0.3756 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I01 compound treatment 416870.0 -169000.0 -0.45 770260.0 204000.0 0.56 0.0767 0.1064 3071008 BCB03_000792 CC[C@H](C)C(=O)O[C@H]1CC[C@@]2(C)C(CCC3=C2CC[C@]4(C)[C@H](CC[C@@]34C)[C@H](C)CCCC(C)C)C1(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I02 compound treatment 822740.0 236000.0 0.63 875720.0 310000.0 0.85 1.048 0.9893 3563155 BCB03_000793 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I03 compound treatment 325520.0 -261000.0 -0.7 477820.0 -88100.0 -0.24 -0.6636 -0.9 3188792 BCB03_000794 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)CCl)C(C)(C)C4CC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I04 compound treatment 255250.0 -331000.0 -0.88 430820.0 -135000.0 -0.37 -0.8875 -0.9256 3563156 BCB03_000795 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I05 mock treatment 870490.0 284000.0 0.76 794180.0 228000.0 0.63 0.9798 0.9955 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I06 mock treatment 776810.0 191000.0 0.51 804060.0 238000.0 0.65 0.8221 0.9923 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I07 compound treatment 345290.0 -241000.0 -0.64 769780.0 204000.0 0.56 -0.0595 -0.0697 3188805 BCB03_000796 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)C(C)(C)C)C(C)(C)C4CC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I08 compound treatment 254830.0 -331000.0 -0.89 262470.0 -303000.0 -0.83 -1.2151 -0.9995 3563157 BCB03_000797 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C=C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I09 compound treatment 506940.0 -79300.0 -0.21 319200.0 -247000.0 -0.68 -0.6289 -0.886 3188806 BCB03_000798 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccccc5)C(C)(C)C4CC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I10 compound treatment 207280.0 -379000.0 -1.01 205040.0 -361000.0 -0.99 -1.4164 -0.9999 3563158 BCB03_000799 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C4CC4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I11 compound treatment 657390.0 71100.0 0.19 369860.0 -196000.0 -0.54 -0.2464 -0.4316 3188807 BCB03_000800 COc1ccc(cc1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I12 compound treatment 197170.0 -389000.0 -1.04 278400.0 -288000.0 -0.79 -1.2931 -0.9908 3563159 BCB03_000801 COCC#CC1N(Cc2ccc(OC)cc2)C(C)Cc3cc(OC)c(OC)cc13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I13 compound treatment 688320.0 102000.0 0.27 710080.0 144000.0 0.4 0.4725 0.9834 3071124 BCB03_000802 COc1cccc(c1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I14 compound treatment 220920.0 -365000.0 -0.98 290910.0 -275000.0 -0.76 -1.224 -0.992 3614506 BCB03_000803 CCCCOc1ccc(/C=C/C(=O)NO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I15 compound treatment 436120.0 -150000.0 -0.4 327310.0 -239000.0 -0.66 -0.7469 -0.9723 3188924 BCB03_000804 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(Br)cc5)C(C)(C)C4CC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I16 compound treatment 201070.0 -385000.0 -1.03 182320.0 -384000.0 -1.05 -1.4723 -0.9999 3614510 BCB03_000805 ONC(=O)/C=C/c1ccc(OC2CCCCC2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I17 compound treatment 780920.0 195000.0 0.52 796720.0 231000.0 0.63 0.8156 0.9952 3188925 BCB03_000806 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(N)cc5)C(C)(C)C4CC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I18 compound treatment 399520.0 -187000.0 -0.5 302080.0 -264000.0 -0.72 -0.865 -0.9834 3614513 BCB03_000807 COc1ccc(/C=C/C(=O)NO)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I19 compound treatment 349390.0 -237000.0 -0.63 698720.0 133000.0 0.36 -0.1897 -0.2597 3614517 BCB03_000808 COC(=O)[C@H](Cc1ccccc1)N(CC#C)O[C@@H](/C=C/[C@@H](O)Cc2ccccc2)C3CC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I20 compound treatment 284480.0 -302000.0 -0.81 204180.0 -362000.0 -0.99 -1.2723 -0.9946 3614521 BCB03_000809 ONC(=O)/C=C/c1ccc(O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I21 mock treatment 647080.0 60800.0 0.16 727230.0 161000.0 0.44 0.4279 0.9073 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I22 mock treatment 808050.0 222000.0 0.59 377990.0 -188000.0 -0.52 0.054 0.0687 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I23 compound treatment 653760.0 67500.0 0.18 187230.0 -379000.0 -1.04 -0.6078 -0.5759 3614524 BCB03_000810 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 I24 compound treatment 295320.0 -291000.0 -0.78 235690.0 -330000.0 -0.91 -1.1907 -0.9971 3614525 BCB03_000811 ONC(=O)/C=C/c1ccc(OCCc2ccccc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J01 compound treatment 823750.0 237000.0 0.63 584840.0 18900.0 0.05 0.4852 0.7624 3614528 BCB03_000812 COC(=O)c1cn(CC(=O)Nc2ccon2)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J02 mock treatment 271890.0 -314000.0 -0.84 266950.0 -299000.0 -0.82 -1.1742 -0.9999 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J03 compound treatment 268330.0 -318000.0 -0.85 225890.0 -340000.0 -0.93 -1.2607 -0.9989 3614530 BCB03_000813 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J04 mock treatment 477410.0 -109000.0 -0.29 209340.0 -357000.0 -0.98 -0.8979 -0.8792 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J05 mock treatment 216220.0 -370000.0 -0.99 369020.0 -197000.0 -0.54 -1.0812 -0.9597 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J06 mock treatment 775470.0 189000.0 0.51 679590.0 114000.0 0.31 0.5779 0.9731 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J07 compound treatment 352660.0 -234000.0 -0.62 281540.0 -284000.0 -0.78 -0.9934 -0.9938 3614532 BCB03_000814 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCN(CC4)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J08 mock treatment 426440.0 -160000.0 -0.43 333190.0 -233000.0 -0.64 -0.7537 -0.9808 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J09 compound treatment 459520.0 -127000.0 -0.34 800840.0 235000.0 0.64 0.2166 0.2974 3614534 BCB03_000815 NC(=N)NCc1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J10 mock treatment 576160.0 -10100.0 -0.03 496960.0 -69000.0 -0.19 -0.153 -0.7999 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J11 compound treatment 413760.0 -173000.0 -0.46 231000.0 -335000.0 -0.92 -0.9761 -0.949 3614535 BCB03_000816 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCN(CC3)c4ccccc4)nn2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J12 mock treatment 371380.0 -215000.0 -0.57 479090.0 -86900.0 -0.24 -0.5745 -0.9243 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J13 compound treatment 393540.0 -193000.0 -0.51 516500.0 -49400.0 -0.14 -0.46 -0.864 3614536 BCB03_000817 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCOCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J14 mock treatment 416270.0 -170000.0 -0.45 343710.0 -222000.0 -0.61 -0.7525 -0.9894 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J15 compound treatment 483950.0 -102000.0 -0.27 633880.0 67900.0 0.19 -0.0614 -0.1855 3614537 BCB03_000818 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCOCC3)nn2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J16 mock treatment 343170.0 -243000.0 -0.65 316440.0 -250000.0 -0.69 -0.9435 -0.9996 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J17 compound treatment 652520.0 66200.0 0.18 274000.0 -292000.0 -0.8 -0.4417 -0.5381 3556424 BCB03_000819 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J18 mock treatment 475410.0 -111000.0 -0.3 251160.0 -315000.0 -0.86 -0.8205 -0.8981 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J19 compound treatment 336700.0 -250000.0 -0.67 628030.0 62100.0 0.17 -0.3509 -0.5099 3614538 BCB03_000820 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCn3cc(nn3)c4ccccc4N 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J20 mock treatment 291040.0 -295000.0 -0.79 787000.0 221000.0 0.61 -0.1285 -0.1291 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J21 mock treatment 292960.0 -293000.0 -0.78 737060.0 171000.0 0.47 -0.2218 -0.2428 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J22 mock treatment 631270.0 45000.0 0.12 623960.0 58000.0 0.16 0.1976 0.9903 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J23 compound treatment 613760.0 27500.0 0.07 292710.0 -273000.0 -0.75 -0.4785 -0.6349 3614540 BCB03_000821 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCn3cc(nn3)c4ccccc4N 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 J24 mock treatment 727430.0 141000.0 0.38 319460.0 -246000.0 -0.68 -0.2119 -0.2736 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K01 compound treatment 5240.0 -581000.0 -1.55 5690.0 -560000.0 -1.54 -2.185 -1.0 3614545 BCB03_000822 COC(=O)[C@H](Cc1ccccc1)N2CC3=CC(=O)[C@H](C4CC4)[C@H]3[C@@H]2[C@@H](O)Cc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K02 compound treatment 216420.0 -370000.0 -0.99 380360.0 -186000.0 -0.51 -1.0588 -0.9526 3614548 BCB03_000823 COc1ccc(CCCOc2ccc(/C=C/C(=O)NO)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K03 compound treatment 6100.0 -580000.0 -1.55 6460.0 -559000.0 -1.54 -2.1819 -1.0 3614553 BCB03_000824 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)[C@@H]3Cc6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K04 compound treatment 509810.0 -76500.0 -0.2 394780.0 -171000.0 -0.47 -0.4767 -0.9304 3614558 BCB03_000825 ONC(=O)/C=C/c1ccc(OCCc2ccccn2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K05 compound treatment 188500.0 -398000.0 -1.06 145330.0 -421000.0 -1.15 -1.5678 -0.9991 3614560 BCB03_000826 COC(=O)C1(CCCC1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K06 compound treatment 278040.0 -308000.0 -0.82 267330.0 -299000.0 -0.82 -1.1619 -1.0 3614562 BCB03_000827 ONC(=O)/C=C/c1ccc(OCCNCc2ccccc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K07 mock treatment 365710.0 -221000.0 -0.59 587160.0 21200.0 0.06 -0.3754 -0.6341 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K08 mock treatment 889040.0 303000.0 0.81 849540.0 284000.0 0.78 1.1224 0.9998 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K09 compound treatment 389450.0 -197000.0 -0.53 834410.0 268000.0 0.74 0.1494 0.165 3614565 BCB03_000828 C=C/C=C/[C@H]1[C@@H]2[C@H](Cc3ccccc3)OC(=O)C4(CCCC4)N2CC1=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K10 compound treatment 316570.0 -270000.0 -0.72 366450.0 -199000.0 -0.55 -0.8967 -0.9909 1065487 BCB03_000829 ONC(=O)CCCc1ccccc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K11 compound treatment 459910.0 -126000.0 -0.34 314080.0 -252000.0 -0.69 -0.7276 -0.9456 3614570 BCB03_000830 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3C51CCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K12 compound treatment 684280.0 98000.0 0.26 518400.0 -47500.0 -0.13 0.0928 0.3172 3614573 BCB03_000831 CCCC(CCC)C(=O)NO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K13 compound treatment 770610.0 184000.0 0.49 773240.0 207000.0 0.57 0.7506 0.9974 3614575 BCB03_000832 COC(=O)C1(CCCC1)N2CC3=C[C@@H]([C@@H](O)Cc4ccccc4)n5n([C@@H]3[C@H](O2)C6CC6)c(=O)n(C)c5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K14 compound treatment 789560.0 203000.0 0.54 857180.0 291000.0 0.8 0.9493 0.9822 3614578 BCB03_000833 Oc1ccc2ncnc(NCC=C)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K15 mock treatment 713140.0 127000.0 0.34 389760.0 -176000.0 -0.48 -0.1024 -0.1735 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K16 mock treatment 630790.0 44500.0 0.12 662330.0 96400.0 0.26 0.2712 0.9348 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K17 compound treatment 738240.0 152000.0 0.41 536320.0 -29600.0 -0.08 0.2295 0.5544 3614579 BCB03_000834 COC(=O)C1(CCCC1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K18 compound treatment 850560.0 264000.0 0.71 787220.0 221000.0 0.61 0.9287 0.9972 3614582 BCB03_000835 CCCNc1ncnc2ccc(O)cc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K19 compound treatment 340830.0 -245000.0 -0.66 519080.0 -46900.0 -0.13 -0.5546 -0.8301 3614584 BCB03_000836 COC(=O)C1(CCCC1)N2C[C@](C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K20 compound treatment 243560.0 -343000.0 -0.92 720210.0 154000.0 0.42 -0.3478 -0.3448 2065681 BCB03_000837 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K21 compound treatment 714210.0 128000.0 0.34 284480.0 -281000.0 -0.77 -0.3048 -0.3607 3614590 BCB03_000838 COC(=O)C1(CCCC1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K22 compound treatment 657760.0 71500.0 0.19 458560.0 -107000.0 -0.29 -0.0735 -0.2092 3216001 BCB03_000839 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K23 mock treatment 778090.0 192000.0 0.51 289350.0 -277000.0 -0.76 -0.1747 -0.1907 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 K24 mock treatment 835680.0 249000.0 0.67 324030.0 -242000.0 -0.66 0.0014 0.0015 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L01 compound treatment 779370.0 193000.0 0.52 835880.0 270000.0 0.74 0.8887 0.9843 3614594 BCB03_000840 Nc1ccccc1c2cn(CC(=O)Nc3nccs3)nn2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L02 mock treatment 831430.0 245000.0 0.65 885990.0 320000.0 0.88 1.0843 0.9895 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L03 compound treatment 830400.0 244000.0 0.65 750140.0 184000.0 0.51 0.8186 0.9921 3614596 BCB03_000841 Nc1ccccc1c2cn(CC(=O)Nc3ccon3)nn2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L04 mock treatment 350690.0 -236000.0 -0.63 824000.0 258000.0 0.71 0.056 0.0591 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L05 compound treatment 412450.0 -174000.0 -0.46 843120.0 277000.0 0.76 0.2098 0.2353 3556414 BCB03_000842 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L06 mock treatment 648520.0 62200.0 0.17 801780.0 236000.0 0.65 0.5754 0.8607 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L07 mock treatment 562250.0 -24000.0 -0.06 681380.0 115000.0 0.32 0.1787 0.5527 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L08 mock treatment 739230.0 153000.0 0.41 486170.0 -79800.0 -0.22 0.134 0.2891 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L09 compound treatment 416480.0 -170000.0 -0.45 527360.0 -38600.0 -0.11 -0.3956 -0.8494 3556416 BCB03_000843 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L10 mock treatment 350560.0 -236000.0 -0.63 360590.0 -205000.0 -0.56 -0.8439 -0.9985 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L11 compound treatment 701760.0 115000.0 0.31 482040.0 -83900.0 -0.23 0.0552 0.1434 3614599 BCB03_000844 CN1C(=O)[C@@H]2[C@H](C1=O)[C@]34COC[C@@H](N4C(=O)[C@@]2(O3)C(=O)C)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L12 mock treatment 776640.0 190000.0 0.51 758500.0 193000.0 0.53 0.7333 0.9998 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L13 compound treatment 640710.0 54400.0 0.15 560690.0 -5260.0 -0.01 0.0926 0.6338 3614605 BCB03_000845 Cc1ccc(cc1)S(=O)(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L14 mock treatment 737120.0 151000.0 0.4 750720.0 185000.0 0.51 0.6436 0.9935 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L15 mock treatment 758940.0 173000.0 0.46 390180.0 -176000.0 -0.48 -0.0151 -0.0227 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L16 mock treatment 596520.0 10200.0 0.03 474410.0 -91500.0 -0.25 -0.1584 -0.6265 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L17 compound treatment 631230.0 44900.0 0.12 738840.0 173000.0 0.47 0.4205 0.8589 3614607 BCB03_000846 CN1C(=O)[C@H]2[C@@H](C1=O)[C@@]34COC[C@@H](N4C(=O)[C@]2(O3)C(=O)C)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L18 mock treatment 562990.0 -23300.0 -0.06 577470.0 11500.0 0.03 -0.0216 -0.3098 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L19 compound treatment 849800.0 264000.0 0.7 811530.0 246000.0 0.67 0.9745 0.9998 3614609 BCB03_000847 CC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L20 mock treatment 416570.0 -170000.0 -0.45 758560.0 193000.0 0.53 0.0534 0.0767 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L21 compound treatment 714850.0 129000.0 0.34 647320.0 81400.0 0.22 0.4008 0.9783 3614611 BCB03_000848 CC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L22 mock treatment 775390.0 189000.0 0.51 738530.0 173000.0 0.47 0.6922 0.9995 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L23 mock treatment 605720.0 19400.0 0.05 282320.0 -284000.0 -0.78 -0.5139 -0.6585 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 L24 mock treatment 718460.0 132000.0 0.35 819370.0 253000.0 0.7 0.7416 0.9505 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M01 compound treatment 8840.0 -577000.0 -1.54 8340.0 -558000.0 -1.53 -2.1731 -1.0 3614612 BCB03_000849 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@@H]3[C@@H](O)Cc6ccccc6)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M02 compound treatment 798600.0 212000.0 0.57 720540.0 155000.0 0.42 0.7011 0.9898 3215997 BCB03_000850 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M03 compound treatment 264960.0 -321000.0 -0.86 742450.0 177000.0 0.48 -0.2642 -0.2681 3614614 BCB03_000851 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC(=C)[C@@H](/C=C/C=C)[C@@H]3[C@@H](O)Cc4ccccc4)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M04 compound treatment 480720.0 -106000.0 -0.28 409210.0 -157000.0 -0.43 -0.5036 -0.979 3216003 BCB03_000852 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M05 compound treatment 17770.0 -569000.0 -1.52 21630.0 -544000.0 -1.49 -2.1304 -1.0 3614616 BCB03_000853 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)C63CCCC6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M06 compound treatment 473720.0 -113000.0 -0.3 633990.0 68000.0 0.19 -0.0805 -0.2274 3215999 BCB03_000854 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(C)C3=O)c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M07 compound treatment 313930.0 -272000.0 -0.73 340710.0 -225000.0 -0.62 -0.9516 -0.9967 3614620 BCB03_000855 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M08 compound treatment 517020.0 -69300.0 -0.18 306180.0 -260000.0 -0.71 -0.6351 -0.862 3215995 BCB03_000856 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)COc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M09 mock treatment 669570.0 83300.0 0.22 716770.0 151000.0 0.41 0.4501 0.9576 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M10 mock treatment 579740.0 -6540.0 -0.02 781810.0 216000.0 0.59 0.4067 0.686 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M11 compound treatment 356000.0 -230000.0 -0.62 369300.0 -197000.0 -0.54 -0.8167 -0.9979 3614624 BCB03_000857 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M12 compound treatment 701200.0 115000.0 0.31 649730.0 83800.0 0.23 0.3797 0.9899 3215892 BCB03_000858 CC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M13 mock treatment 665280.0 79000.0 0.21 528580.0 -37400.0 -0.1 0.0767 0.3267 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M14 mock treatment 726430.0 140000.0 0.37 769950.0 204000.0 0.56 0.6607 0.9808 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M15 compound treatment 483360.0 -103000.0 -0.27 345510.0 -220000.0 -0.61 -0.6223 -0.9362 3614627 BCB03_000859 O[C@@H](Cc1ccccc1)[C@H]2O[C@@H](Cc3ccccc3)[C@@H](/C=C/C4CC4)N2CC#C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M16 compound treatment 716050.0 130000.0 0.35 331770.0 -234000.0 -0.64 -0.2095 -0.2869 3215890 BCB03_000860 COCC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M17 compound treatment 386080.0 -200000.0 -0.53 724900.0 159000.0 0.44 -0.0695 -0.1008 3562141 BCB03_000861 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@H](/C=C/C3CC3)[C@@H](O)Cc4ccccc4)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M18 compound treatment 584050.0 -2230.0 -0.01 563540.0 -2410.0 -0.01 -0.0089 -0.9987 3215888 BCB03_000862 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@H](O1)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M19 compound treatment 620640.0 34400.0 0.09 462690.0 -103000.0 -0.28 -0.1356 -0.455 3614632 BCB03_000863 O=C1O[C@H](C2CCCCC2)[C@H](/C=C/C3CC3)N(CC#C)C1Cc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M20 compound treatment 401460.0 -185000.0 -0.49 716740.0 151000.0 0.41 -0.0563 -0.0874 3215943 BCB03_000864 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M21 compound treatment 583410.0 -2870.0 -0.01 694370.0 128000.0 0.35 0.2439 0.6916 3614636 BCB03_000865 O=C1O[C@@H]([C@@H]2[C@H]3C=CCCC=C3CN2C1Cc4ccccc4)C5CCCCC5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M22 compound treatment 370080.0 -216000.0 -0.58 377120.0 -189000.0 -0.52 -0.7749 -0.9986 3215941 BCB03_000866 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M23 compound treatment 802580.0 216000.0 0.58 398240.0 -168000.0 -0.46 0.0829 0.1123 3614641 BCB03_000867 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3[C@H](/C=C/C4CC4)[C@H](Cc5ccccc5)OC3=O)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 M24 compound treatment 385340.0 -201000.0 -0.54 194360.0 -372000.0 -1.02 -1.1009 -0.955 3215939 BCB03_000868 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)c6ccccc6C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N01 compound treatment 651680.0 65400.0 0.17 871800.0 306000.0 0.84 0.7173 0.8363 3614646 BCB03_000869 C=CCOC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N02 mock treatment 815200.0 229000.0 0.61 900770.0 335000.0 0.92 1.0823 0.9804 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N03 compound treatment 839360.0 253000.0 0.68 743170.0 177000.0 0.49 0.822 0.987 3614650 BCB03_000870 C=CCOC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N04 mock treatment 837370.0 251000.0 0.67 358340.0 -208000.0 -0.57 0.0712 0.0809 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N05 compound treatment 472640.0 -114000.0 -0.3 400520.0 -165000.0 -0.45 -0.5358 -0.9808 3614652 BCB03_000871 O=C(NCc1ccccc1)[C@@]2(O[C@@]34COC[C@@H](N4C2=O)c5ccccc5)[C@H]6[C@@H]3C(=O)N(C6=O)c7ccccc7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N06 mock treatment 772190.0 186000.0 0.5 541000.0 -24900.0 -0.07 0.3027 0.6039 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N07 compound treatment 666460.0 80200.0 0.21 793680.0 228000.0 0.63 0.5935 0.8981 3614656 BCB03_000872 O=C(NCCc1c[nH]c2ccccc12)[C@@]3(O[C@@]45COC[C@@H](N5C3=O)c6ccccc6)[C@H]7[C@@H]4C(=O)N(C7=O)c8ccccc8 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N08 mock treatment 701600.0 115000.0 0.31 772060.0 206000.0 0.57 0.6179 0.9591 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N09 mock treatment 602640.0 16400.0 0.04 793280.0 227000.0 0.62 0.4722 0.7548 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N10 mock treatment 798320.0 212000.0 0.57 795160.0 229000.0 0.63 0.8454 0.9986 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N11 compound treatment 624480.0 38200.0 0.1 810950.0 245000.0 0.67 0.5478 0.8052 3614660 BCB03_000873 COC(=O)c1c(COC[C@@H](NC(=O)N(C)Cc2ccccc2)c3ccccc3)oc(C(=O)OCC=C)c1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N12 mock treatment 841760.0 255000.0 0.68 457440.0 -109000.0 -0.3 0.2719 0.3651 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N13 mock treatment 655750.0 69500.0 0.19 511620.0 -54300.0 -0.15 0.0257 0.1081 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N14 mock treatment 516880.0 -69400.0 -0.19 798160.0 232000.0 0.64 0.3197 0.4816 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N15 compound treatment 786590.0 200000.0 0.54 846090.0 280000.0 0.77 0.9222 0.9843 3614664 BCB03_000874 COc1cc(/C=C(\C#N)/C(=O)Nc2nnc(s2)C(F)(F)F)ccc1OCc3ccc(cc3C(F)(F)F)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N16 mock treatment 831740.0 245000.0 0.66 474560.0 -91400.0 -0.25 0.2862 0.4077 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N17 compound treatment 610670.0 24400.0 0.07 579620.0 13700.0 0.04 0.0726 0.9657 1917883 BCB03_000875 O/N=C/1\C2(CCCCC2)C(=O)N(O)C31CCCC=C3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N18 mock treatment 481120.0 -105000.0 -0.28 514420.0 -51500.0 -0.14 -0.2986 -0.9496 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N19 compound treatment 501570.0 -84700.0 -0.23 457830.0 -108000.0 -0.3 -0.3699 -0.991 3614668 BCB03_000876 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)c9cc%10ccccc%10s9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N20 mock treatment 801210.0 215000.0 0.57 436490.0 -129000.0 -0.36 0.1546 0.229 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N21 compound treatment 603550.0 17300.0 0.05 551300.0 -14600.0 -0.04 0.0042 0.0683 3614669 BCB03_000877 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)C9CCCCC9 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N22 mock treatment 700320.0 114000.0 0.3 315420.0 -251000.0 -0.69 -0.271 -0.3602 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N23 compound treatment 642150.0 55900.0 0.15 682240.0 116000.0 0.32 0.3313 0.94 3614671 BCB03_000878 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)C(=O)N)C(=C5)C(=O)c7ccc(F)c(F)c7 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 N24 mock treatment 483540.0 -103000.0 -0.27 735520.0 170000.0 0.47 0.1351 0.2501 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O01 compound treatment 607120.0 20800.0 0.06 575160.0 9210.0 0.03 0.0572 0.9363 3614673 BCB03_000879 COC(=O)[C@H](Cc1ccccc1)N2[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O02 compound treatment 744660.0 158000.0 0.42 676690.0 111000.0 0.3 0.5141 0.9869 2065712 BCB03_000880 CC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O03 compound treatment 780570.0 194000.0 0.52 452070.0 -114000.0 -0.31 0.1459 0.2408 3614677 BCB03_000881 COC(=O)C1(CCCC1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O04 compound treatment 341070.0 -245000.0 -0.65 772110.0 206000.0 0.57 -0.0629 -0.0727 3215981 BCB03_000882 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O05 compound treatment 356970.0 -229000.0 -0.61 429960.0 -136000.0 -0.37 -0.6971 -0.9718 3614680 BCB03_000883 COC(=O)[C@H](Cc1ccccc1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O06 compound treatment 303520.0 -283000.0 -0.76 694460.0 129000.0 0.35 -0.2846 -0.3414 3215977 BCB03_000884 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)c3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O07 compound treatment 484000.0 -102000.0 -0.27 749280.0 183000.0 0.5 0.1627 0.2841 3563099 BCB03_000885 COC(=O)C1=CN(C)C(C)c2ccccc2C=C1C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O08 compound treatment 575360.0 -10900.0 -0.03 565870.0 -77.3 0.0 -0.0208 -0.7122 2065737 BCB03_000886 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O09 compound treatment 499930.0 -86400.0 -0.23 480320.0 -85600.0 -0.24 -0.3293 -1.0 3563100 BCB03_000887 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@H](C)c3ccccc23 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O10 compound treatment 561970.0 -24300.0 -0.06 607780.0 41800.0 0.11 0.0353 0.2675 3215979 BCB03_000888 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O11 mock treatment 627580.0 41300.0 0.11 665160.0 99200.0 0.27 0.2706 0.9208 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O12 mock treatment 651200.0 64900.0 0.17 533030.0 -32900.0 -0.09 0.0587 0.3002 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O13 compound treatment 620130.0 33800.0 0.09 462560.0 -103000.0 -0.28 -0.1368 -0.4592 3563102 BCB03_000889 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C)c3ccccc23 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O14 compound treatment 408730.0 -178000.0 -0.47 466690.0 -99300.0 -0.27 -0.528 -0.9654 3215975 BCB03_000890 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O15 compound treatment 727300.0 141000.0 0.38 646720.0 80800.0 0.22 0.4231 0.9681 3563103 BCB03_000891 CC1N(C)/C(=N\P(=O)(Oc2ccccc2)Oc3ccccc3)/Cc4ccccc14 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O16 compound treatment 597120.0 10800.0 0.03 553530.0 -12400.0 -0.03 -0.0036 -0.0813 3215878 BCB03_000892 CC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O17 compound treatment 678650.0 92400.0 0.25 759520.0 194000.0 0.53 0.5502 0.9391 3563106 BCB03_000893 CN/1C(C=C)c2ccccc2C\C1=N\P(=O)(Oc3ccccc3)Oc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O18 compound treatment 486560.0 -99700.0 -0.27 683760.0 118000.0 0.32 0.0404 0.0963 3215876 BCB03_000894 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O19 compound treatment 616700.0 30400.0 0.08 593180.0 27200.0 0.07 0.1103 0.9991 3563109 BCB03_000895 CCOC(=O)C1=C2[C@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O20 compound treatment 293920.0 -292000.0 -0.78 469180.0 -96800.0 -0.27 -0.74 -0.8972 3215874 BCB03_000896 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O21 compound treatment 655750.0 69500.0 0.19 748280.0 182000.0 0.5 0.4852 0.9088 3563111 BCB03_000897 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O22 compound treatment 235640.0 -351000.0 -0.94 290090.0 -276000.0 -0.76 -1.1978 -0.9944 3216007 BCB03_000898 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O23 compound treatment 781160.0 195000.0 0.52 768570.0 203000.0 0.56 0.7614 0.9994 3563112 BCB03_000899 CN/1C(C2CC2)c3ccccc3C\C1=N\P(=O)(Oc4ccccc4)Oc5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 O24 compound treatment 602290.0 16000.0 0.04 310770.0 -255000.0 -0.7 -0.4651 -0.6627 3216011 BCB03_000900 COC[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P01 compound treatment 282080.0 -304000.0 -0.81 437550.0 -128000.0 -0.35 -0.8238 -0.9301 3614688 BCB03_000901 COc1ccc(cc1OC2CCCC2)C3=NOC(C3)C(=O)NO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P02 mock treatment 647070.0 60800.0 0.16 620500.0 54600.0 0.15 0.2207 0.9992 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P03 compound treatment 408990.0 -177000.0 -0.47 316860.0 -249000.0 -0.68 -0.8184 -0.9839 3614690 BCB03_000902 CC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P04 mock treatment 355210.0 -231000.0 -0.62 454560.0 -111000.0 -0.31 -0.6527 -0.9475 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P05 compound treatment 438560.0 -148000.0 -0.39 384560.0 -181000.0 -0.5 -0.6311 -0.9934 3614693 BCB03_000903 COC(=O)c1cn(CC(=O)O)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P06 mock treatment 409480.0 -177000.0 -0.47 470190.0 -95800.0 -0.26 -0.5198 -0.9618 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P07 compound treatment 415560.0 -171000.0 -0.46 572840.0 6890.0 0.02 -0.3091 -0.6772 3614695 BCB03_000904 COC(=O)c1cn(CCC(=O)O)nn1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P08 mock treatment 406730.0 -180000.0 -0.48 470680.0 -95300.0 -0.26 -0.5241 -0.9593 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P09 compound treatment 326840.0 -259000.0 -0.69 331580.0 -234000.0 -0.64 -0.945 -0.9993 1366116 BCB03_000905 Brc1ccc2ncnc(NCC=C)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P10 mock treatment 399880.0 -186000.0 -0.5 449380.0 -117000.0 -0.32 -0.5783 -0.9772 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P11 mock treatment 396710.0 -190000.0 -0.51 572980.0 7030.0 0.02 -0.3444 -0.6796 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P12 mock treatment 384230.0 -202000.0 -0.54 353350.0 -213000.0 -0.58 -0.7943 -0.9992 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P13 compound treatment 309850.0 -276000.0 -0.74 364000.0 -202000.0 -0.55 -0.9141 -0.99 1263689 BCB03_000906 Brc1ccc2ncnc(NCc3ccccc3)c2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P14 mock treatment 467940.0 -118000.0 -0.32 425160.0 -141000.0 -0.39 -0.4968 -0.995 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P15 compound treatment 342450.0 -244000.0 -0.65 334630.0 -231000.0 -0.64 -0.9096 -0.9999 1385097 BCB03_000907 CCCNc1ncnc2ccc(Br)cc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P16 mock treatment 258160.0 -328000.0 -0.88 291110.0 -275000.0 -0.75 -1.1533 -0.9972 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P17 compound treatment 265680.0 -321000.0 -0.86 269010.0 -297000.0 -0.82 -1.182 -0.9997 3614697 BCB03_000908 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccc(Br)cc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P18 mock treatment 261250.0 -325000.0 -0.87 440690.0 -125000.0 -0.34 -0.857 -0.9178 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P19 compound treatment 518680.0 -67600.0 -0.18 291360.0 -275000.0 -0.75 -0.6607 -0.8524 3614698 BCB03_000909 CCOc1ncnc2ccc(Br)cc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P20 mock treatment 277950.0 -308000.0 -0.82 212680.0 -353000.0 -0.97 -1.2681 -0.9967 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P21 compound treatment 504970.0 -81300.0 -0.22 236010.0 -330000.0 -0.91 -0.7941 -0.8525 1985613 BCB03_000910 C=CCNc1ncnc2ccccc12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P22 mock treatment 397280.0 -189000.0 -0.5 253200.0 -313000.0 -0.86 -0.9641 -0.9679 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P23 compound treatment 327360.0 -259000.0 -0.69 269870.0 -296000.0 -0.81 -1.0638 -0.9968 1412880 BCB03_000911 C(Nc1ncnc2ccccc12)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2283 P24 mock treatment 514530.0 -71800.0 -0.19 341030.0 -225000.0 -0.62 -0.5721 -0.8849 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A01 mock treatment 232340.0 -330000.0 -0.88 310080.0 -226000.0 -0.62 -1.063 -0.9852 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A02 compound treatment 652340.0 89600.0 0.24 577920.0 41600.0 0.11 0.2502 0.9428 3555546 CMLD3_000001 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A03 mock treatment 297950.0 -265000.0 -0.71 262410.0 -274000.0 -0.75 -1.0317 -0.9995 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A04 compound treatment 669060.0 106000.0 0.28 651860.0 116000.0 0.32 0.4253 0.9985 3555566 CMLD3_000002 COc1ccc2C(=O)[C@@H](OC(=O)NCCOc3ccccc3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A05 compound treatment 368640.0 -194000.0 -0.52 724720.0 188000.0 0.52 -7.0E-4 -9.0E-4 3555570 CMLD3_000003 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A06 compound treatment 398500.0 -164000.0 -0.44 332730.0 -204000.0 -0.56 -0.7052 -0.9928 3555574 CMLD3_000004 COc1ccc2O[C@H]([C@H](O)C(=O)c2c1)c3ccc(OC)c(Br)c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A07 mock treatment 511150.0 -51500.0 -0.14 554310.0 18000.0 0.05 -0.0623 -0.426 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A08 compound treatment 448290.0 -114000.0 -0.31 317350.0 -219000.0 -0.6 -0.6411 -0.9508 3555579 CMLD3_000005 COc1ccc2O[C@H]([C@H](OC(=O)NCCOc3ccccc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A09 compound treatment 702000.0 139000.0 0.37 435480.0 -101000.0 -0.28 0.0674 0.1454 3555584 CMLD3_000006 Brc1ccc2O[C@H]([C@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc6OCOc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A10 compound treatment 680130.0 117000.0 0.31 420640.0 -116000.0 -0.32 -0.0027 -0.006 3555589 CMLD3_000007 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@@H]1Cc2cc(Br)ccc2O[C@H]1c3cccc(OC)c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A11 mock treatment 538690.0 -24000.0 -0.06 377690.0 -159000.0 -0.44 -0.3532 -0.8026 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A12 compound treatment 525940.0 -36800.0 -0.1 349620.0 -187000.0 -0.51 -0.4318 -0.8275 3555594 CMLD3_000008 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A13 mock treatment 606740.0 44000.0 0.12 665390.0 129000.0 0.35 0.3338 0.8939 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A14 mock treatment 570790.0 8100.0 0.02 723650.0 187000.0 0.51 0.3791 0.7362 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A15 compound treatment 239010.0 -324000.0 -0.86 328670.0 -208000.0 -0.57 -1.0144 -0.9796 3555598 CMLD3_000009 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)c2cc(C)cc(C)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A16 compound treatment 790250.0 228000.0 0.61 606340.0 70100.0 0.19 0.5658 0.8875 3555600 CMLD3_000010 Cc1cc(C)cc(/C=C/[C@H]2OC[C@@H](O)[C@H]2Oc3ccc(cc3)C4CCCC4)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A17 compound treatment 275410.0 -287000.0 -0.77 200850.0 -335000.0 -0.92 -1.1937 -0.9959 3555605 CMLD3_000011 COc1ccc(C#C[C@H]2O[C@H](CO)[C@@H](Oc3cc(C)cc(C)c3)C=C2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A18 compound treatment 19380.0 -543000.0 -1.45 19310.0 -517000.0 -1.42 -2.0297 -0.9999 3555609 CMLD3_000012 CC(C)(C)OC(=O)C1=NOC2(C1)C=CC(=O)C=C2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A19 compound treatment 556050.0 -6640.0 -0.02 788820.0 253000.0 0.69 0.4777 0.6888 3555611 CMLD3_000013 COC(=O)N[C@@H](c1ccccc1)[C@@]2(CCCC2=O)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A20 compound treatment 632800.0 70100.0 0.19 491240.0 -45000.0 -0.12 0.045 0.2005 3555615 CMLD3_000014 CCCCCCCC#Cc1ccccc1C(NC(=O)OC)C(C(=O)OC)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A21 compound treatment 665120.0 102000.0 0.27 530240.0 -6030.0 -0.02 0.1817 0.6631 3555617 CMLD3_000015 CC(C)(C)OC1C2C3C2C4C1C3CC=CC4(O)CC=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A22 compound treatment 616250.0 53600.0 0.14 757680.0 221000.0 0.61 0.531 0.8503 3555619 CMLD3_000016 COCn1c2ccccc2c3nnc(nc13)C(=O)O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A23 compound treatment 403410.0 -159000.0 -0.43 290670.0 -246000.0 -0.67 -0.7776 -0.9753 3555621 CMLD3_000017 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2cccs2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 A24 compound treatment 479770.0 -82900.0 -0.22 268230.0 -268000.0 -0.74 -0.677 -0.8809 3555626 CMLD3_000018 CC(=CCC/C(=C/C=C/C1=CC2(C)CC1(C)C(CC2=O)\C=C(/C)\CCC=C(C)C)/C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B01 compound treatment 599370.0 36700.0 0.1 826930.0 291000.0 0.8 0.6335 0.788 3555630 CMLD3_000019 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B02 compound treatment 262560.0 -300000.0 -0.8 179160.0 -357000.0 -0.98 -1.2601 -0.995 3555635 CMLD3_000020 COc1ccc2C(=O)[C@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B03 compound treatment 755520.0 193000.0 0.52 629630.0 93400.0 0.26 0.5454 0.9481 3555639 CMLD3_000021 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B04 compound treatment 763530.0 201000.0 0.54 731460.0 195000.0 0.54 0.7582 1.0 3555643 CMLD3_000022 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@@H](Oc2c1)c5ccc6OCOc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B05 compound treatment 634130.0 71400.0 0.19 709090.0 173000.0 0.47 0.4704 0.9199 3555647 CMLD3_000023 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3ccc4OCOc4c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B06 compound treatment 609620.0 46900.0 0.13 551210.0 14900.0 0.04 0.1176 0.8919 3555651 CMLD3_000024 COc1ccc2C(=O)[C@H](O)[C@H](Oc2c1)c3ccc4OCOc4c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B07 compound treatment 416810.0 -146000.0 -0.39 503560.0 -32700.0 -0.09 -0.339 -0.8479 3555653 CMLD3_000025 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B08 compound treatment 738110.0 175000.0 0.47 647230.0 111000.0 0.3 0.5467 0.9783 3555657 CMLD3_000026 COc1ccc2C(=O)[C@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@H](Oc2c1)c5ccc6OCOc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B09 compound treatment 682330.0 120000.0 0.32 524280.0 -12000.0 -0.03 0.2027 0.6309 3555659 CMLD3_000027 COc1ccc2C(=O)[C@H](OC(=O)N[C@H](C)C3CCCCC3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B10 compound treatment 742360.0 180000.0 0.48 709280.0 173000.0 0.47 0.6752 1.0 3555663 CMLD3_000028 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B11 compound treatment 517530.0 -45200.0 -0.12 430470.0 -106000.0 -0.29 -0.2907 -0.9242 3555666 CMLD3_000029 COc1ccc2O[C@H]([C@H](OC(=O)Nc3ccc(C)c(Br)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B12 compound treatment 710960.0 148000.0 0.4 700960.0 165000.0 0.45 0.5997 0.9978 3555670 CMLD3_000030 COc1ccc2C(=O)[C@H](OC(=O)NCCOc3ccccc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B13 mock treatment 519260.0 -43400.0 -0.12 664320.0 128000.0 0.35 0.1665 0.4499 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B14 mock treatment 477470.0 -85200.0 -0.23 556850.0 20600.0 0.06 -0.121 -0.516 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B15 compound treatment 576070.0 13400.0 0.04 276390.0 -260000.0 -0.71 -0.4792 -0.6709 3555672 CMLD3_000031 CC(=O)c1ccc(cc1)[C@H]2O[C@H](CO)[C@@H](Oc3ccc(cc3)c4ccccc4)C=C2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B16 compound treatment 591700.0 29000.0 0.08 547100.0 10800.0 0.03 0.0758 0.9135 3555676 CMLD3_000032 CC(C)(C)c1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccccc3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B17 compound treatment 303130.0 -260000.0 -0.69 244480.0 -292000.0 -0.8 -1.0567 -0.9974 3555680 CMLD3_000033 CC(=O)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(Br)cc3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B18 compound treatment 587360.0 24700.0 0.07 464010.0 -72300.0 -0.2 -0.0937 -0.4482 3555686 CMLD3_000034 COc1ccc(/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4ccc(OC)cc4)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B19 compound treatment 567910.0 5220.0 0.01 303560.0 -233000.0 -0.64 -0.4419 -0.6915 3555689 CMLD3_000035 COC(=O)N[C@H](CC(=O)C)c1ccc2OCOc2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B20 mock treatment 336320.0 -226000.0 -0.6 766490.0 230000.0 0.63 0.0194 0.0222 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B21 compound treatment 710080.0 147000.0 0.39 674720.0 138000.0 0.38 0.5471 0.9998 3555694 CMLD3_000036 COCO[C@@H]1[C@@H](C)C(=O)N2[C@@H]1[C@@H](Oc3ccc(OC)cc23)/C=C/C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B22 compound treatment 283110.0 -280000.0 -0.75 461550.0 -74700.0 -0.21 -0.6731 -0.8692 3555700 CMLD3_000037 C[C@@H]1C=CCCO[C@H]1c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B23 compound treatment 821950.0 259000.0 0.69 774960.0 239000.0 0.66 0.953 0.9996 3555703 CMLD3_000038 CCCCCCCC#Cc1ccccc1/C=N/S(=O)c2ccc(C)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 B24 compound treatment 744270.0 182000.0 0.48 693290.0 157000.0 0.43 0.6478 0.9983 3555707 CMLD3_000039 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)c3ccccn3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C01 compound treatment 476850.0 -85800.0 -0.23 630530.0 94300.0 0.26 0.0209 0.0603 3555711 CMLD3_000040 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3[C@H](O)[C@H]2O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C02 compound treatment 678650.0 116000.0 0.31 601050.0 64800.0 0.18 0.3448 0.9653 3555810 CMLD3_000041 COc1ccc2C(=O)[C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C03 compound treatment 765970.0 203000.0 0.54 510460.0 -25800.0 -0.07 0.3338 0.6096 3555814 CMLD3_000042 CCOC(=O)CNC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C04 compound treatment 705690.0 143000.0 0.38 565920.0 29600.0 0.08 0.3276 0.839 3555817 CMLD3_000043 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2[C@H](Oc3ccc(OC)cc3C2=O)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C05 compound treatment 426130.0 -137000.0 -0.36 303480.0 -233000.0 -0.64 -0.7098 -0.9646 3555820 CMLD3_000044 COc1ccc2O[C@@H]([C@@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C06 compound treatment 598660.0 36000.0 0.1 666130.0 130000.0 0.36 0.32 0.8667 3555823 CMLD3_000045 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C07 compound treatment 692550.0 130000.0 0.35 706500.0 170000.0 0.47 0.5757 0.9892 3555825 CMLD3_000046 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3cccc(OC)c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C08 compound treatment 597330.0 34600.0 0.09 595940.0 59700.0 0.16 0.1813 0.9634 3555829 CMLD3_000047 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NC4CCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C09 compound treatment 470460.0 -92200.0 -0.25 620230.0 84000.0 0.23 -0.0112 -0.0332 3555833 CMLD3_000048 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2[C@H](Oc3cc(OC)ccc3C2=O)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C10 compound treatment 527410.0 -35300.0 -0.09 513550.0 -22700.0 -0.06 -0.1107 -0.9799 3555837 CMLD3_000049 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C11 mock treatment 604160.0 41500.0 0.11 507610.0 -28700.0 -0.08 0.0227 0.1669 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C12 mock treatment 499000.0 -63700.0 -0.17 674350.0 138000.0 0.38 0.1478 0.3556 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C13 compound treatment 568640.0 5950.0 0.02 205200.0 -331000.0 -0.91 -0.6315 -0.6946 3555841 CMLD3_000050 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2Cc3cc(OC)ccc3O[C@H]2c4cccc(OC)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C14 compound treatment 578750.0 16100.0 0.04 324580.0 -212000.0 -0.58 -0.3806 -0.6531 3555844 CMLD3_000051 CC(=O)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccc(Cl)cc3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C15 mock treatment 542450.0 -20200.0 -0.05 351260.0 -185000.0 -0.51 -0.3974 -0.778 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C16 mock treatment 644570.0 81900.0 0.22 537300.0 1030.0 0.0 0.1566 0.7162 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C17 compound treatment 217810.0 -345000.0 -0.92 188570.0 -348000.0 -0.95 -1.3264 -0.9998 3555848 CMLD3_000052 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2cccc(c2)N(C)C)C#Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C18 compound treatment 634880.0 72200.0 0.19 674340.0 138000.0 0.38 0.4044 0.9508 3555853 CMLD3_000053 COC(=O)C1(CC2(CCC3C4C5C41)OCCO2)C3C5OCc6ccccc6 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C19 compound treatment 532100.0 -30600.0 -0.08 262440.0 -274000.0 -0.75 -0.5894 -0.7794 3555855 CMLD3_000054 COc1cccc(/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4cccc(OC)c4)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C20 compound treatment 296640.0 -266000.0 -0.71 236670.0 -300000.0 -0.82 -1.0841 -0.9973 3555859 CMLD3_000055 COC(=O)[C@@H]1[C@H]([C@H]2C(=O)c3c(OC)cc(OC)cc3O[C@@]12c4ccc(OC)cc4)c5ccccc5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C21 compound treatment 96440.0 -466000.0 -1.25 100480.0 -436000.0 -1.2 -1.7266 -0.9998 831758 CMLD3_000056 Oc1ccc(/C=C/C(=O)c2ccc(O)cc2O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C22 compound treatment 603140.0 40400.0 0.11 408320.0 -128000.0 -0.35 -0.172 -0.468 3555865 CMLD3_000057 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1cccc(C)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C23 compound treatment 695680.0 133000.0 0.36 285800.0 -250000.0 -0.69 -0.2351 -0.3037 3555869 CMLD3_000058 COC(=O)N[C@H](CC(=O)C)c1ccc(F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 C24 compound treatment 318560.0 -244000.0 -0.65 663600.0 127000.0 0.35 -0.2139 -0.2891 3555873 CMLD3_000059 CCCCCCCC1=CC2=CC(=O)C(C)(O)C(=O)C2=CN1CCCC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D01 compound treatment 325830.0 -237000.0 -0.63 526260.0 -10000.0 -0.03 -0.4668 -0.7371 3555876 CMLD3_000060 Cc1ccc(cc1)S(=O)(=O)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D02 compound treatment 368000.0 -195000.0 -0.52 344000.0 -192000.0 -0.53 -0.741 -1.0 3555884 CMLD3_000061 COc1ccc2C(=O)[C@@H](OC(=O)NC3CCCC3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D03 compound treatment 704550.0 142000.0 0.38 791150.0 255000.0 0.7 0.7627 0.9585 3555888 CMLD3_000062 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D04 mock treatment 560970.0 -1720.0 0.0 603760.0 67500.0 0.19 0.1278 0.6893 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D05 compound treatment 740870.0 178000.0 0.48 556270.0 20000.0 0.05 0.3753 0.7835 3555892 CMLD3_000063 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D06 compound treatment 654990.0 92300.0 0.25 510840.0 -25400.0 -0.07 0.1249 0.4876 3555896 CMLD3_000064 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D07 compound treatment 407580.0 -155000.0 -0.41 385190.0 -151000.0 -0.41 -0.5863 -1.0 3555901 CMLD3_000065 COc1ccc2C(=O)[C@@H](OC(=O)NC3CCCC3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D08 mock treatment 685790.0 123000.0 0.33 524930.0 -11300.0 -0.03 0.2105 0.6373 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D09 compound treatment 696930.0 134000.0 0.36 520960.0 -15300.0 -0.04 0.2238 0.6199 3555905 CMLD3_000066 COc1cc(NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4)cc(OC)c1OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D10 compound treatment 401150.0 -162000.0 -0.43 365650.0 -171000.0 -0.47 -0.6363 -0.9992 3555908 CMLD3_000067 COc1ccc2O[C@@H]([C@@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D11 mock treatment 700660.0 138000.0 0.37 600270.0 64000.0 0.18 0.3848 0.9426 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D12 mock treatment 535270.0 -27400.0 -0.07 268070.0 -268000.0 -0.74 -0.5725 -0.7736 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D13 mock treatment 279300.0 -283000.0 -0.76 670000.0 134000.0 0.37 -0.2756 -0.3276 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D14 compound treatment 389510.0 -173000.0 -0.46 642240.0 106000.0 0.29 -0.1214 -0.2221 3555912 CMLD3_000068 CN(C)c1cccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D15 mock treatment 383960.0 -179000.0 -0.48 360920.0 -175000.0 -0.48 -0.678 -1.0 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D16 mock treatment 598110.0 35400.0 0.09 763280.0 227000.0 0.62 0.5076 0.8052 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D17 compound treatment 486330.0 -76400.0 -0.2 581700.0 45400.0 0.12 -0.056 -0.2344 3555916 CMLD3_000069 OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C=O)cc2)C#Cc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D18 compound treatment 543240.0 -19500.0 -0.05 237380.0 -299000.0 -0.82 -0.617 -0.7504 3555921 CMLD3_000070 COc1ccccc1/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4ccccc4OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D19 compound treatment 20030.0 -543000.0 -1.45 15440.0 -521000.0 -1.43 -2.036 -1.0 3555925 CMLD3_000071 CCC/C=C/C1C(CO)C2(OCC(CC)(CC)CO2)[C@@H]3O[C@@H]3C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D20 compound treatment 646600.0 83900.0 0.22 449210.0 -87100.0 -0.24 -0.0105 -0.0322 3555929 CMLD3_000072 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)C(F)(F)F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D21 compound treatment 509120.0 -53600.0 -0.14 461520.0 -74800.0 -0.21 -0.2463 -0.9845 3555933 CMLD3_000073 COc1ccc(cc1)C(=O)CC(=O)c2c(O)cc(OC)cc2OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D22 compound treatment 434730.0 -128000.0 -0.34 536290.0 16.3 0.0 -0.2416 -0.707 3555935 CMLD3_000074 COC(=O)N[C@@H](c1ccco1)[C@@]2(CCCC2=O)C(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D23 mock treatment 583100.0 20400.0 0.05 336320.0 -200000.0 -0.55 -0.3496 -0.6338 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 D24 compound treatment 556670.0 -6020.0 -0.02 505440.0 -30800.0 -0.08 -0.0712 -0.8267 3555939 CMLD3_000075 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1cccc(F)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E01 mock treatment 739740.0 177000.0 0.47 855220.0 319000.0 0.88 0.9536 0.9582 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E02 mock treatment 886600.0 324000.0 0.87 715280.0 179000.0 0.49 0.9593 0.9641 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E03 mock treatment 789640.0 227000.0 0.61 613670.0 77400.0 0.21 0.5789 0.9012 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E04 compound treatment 376000.0 -187000.0 -0.5 667800.0 132000.0 0.36 -0.0973 -0.158 3555943 CMLD3_000076 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E05 compound treatment 252720.0 -310000.0 -0.83 401670.0 -135000.0 -0.37 -0.8467 -0.9339 3555945 CMLD3_000077 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E06 compound treatment 397780.0 -165000.0 -0.44 329310.0 -207000.0 -0.57 -0.7132 -0.9921 3555948 CMLD3_000078 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E07 compound treatment 503000.0 -59700.0 -0.16 611710.0 75400.0 0.21 0.0337 0.129 3555952 CMLD3_000079 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H](C)C3CCCCC3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E08 compound treatment 728810.0 166000.0 0.44 683840.0 148000.0 0.41 0.6002 0.999 3555954 CMLD3_000080 COc1ccc2O[C@@H]([C@@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc(OC)c(Br)c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E09 mock treatment 726030.0 163000.0 0.44 746430.0 210000.0 0.58 0.7165 0.9905 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E10 mock treatment 608410.0 45700.0 0.12 811000.0 275000.0 0.75 0.6197 0.811 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E11 compound treatment 297760.0 -265000.0 -0.71 289860.0 -246000.0 -0.68 -0.9787 -0.9997 3555958 CMLD3_000081 Brc1ccc2O[C@H]([C@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E12 compound treatment 537480.0 -25200.0 -0.07 480670.0 -55600.0 -0.15 -0.1556 -0.9323 3555962 CMLD3_000082 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E13 compound treatment 660410.0 97700.0 0.26 439710.0 -96600.0 -0.27 -0.0029 -0.0078 3555964 CMLD3_000083 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E14 compound treatment 427850.0 -135000.0 -0.36 703970.0 168000.0 0.46 0.0709 0.1213 3555968 CMLD3_000084 CCOC(=O)OC[C@H]1O[C@H](CCc2ccccc2)CC[C@@H]1Oc3ccc(OC)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E15 compound treatment 240390.0 -322000.0 -0.86 179200.0 -357000.0 -0.98 -1.3019 -0.9979 3555972 CMLD3_000085 CC(C)(C)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E16 compound treatment 153880.0 -409000.0 -1.09 288130.0 -248000.0 -0.68 -1.2538 -0.9742 3555975 CMLD3_000086 CC(C)(C)c1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccccc3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E17 mock treatment 756120.0 193000.0 0.52 744980.0 209000.0 0.57 0.7705 0.9987 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E18 mock treatment 785920.0 223000.0 0.6 685960.0 150000.0 0.41 0.7122 0.9835 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E19 compound treatment 740890.0 178000.0 0.48 210560.0 -326000.0 -0.89 -0.2958 -0.292 3555978 CMLD3_000087 C[C@H](O)CCCCCCC/C=C/C=C/C(=O)N 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E20 compound treatment 754630.0 192000.0 0.51 696650.0 160000.0 0.44 0.6738 0.9971 3555982 CMLD3_000088 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cccc3c4ccccc4oc23)c5cccc6c7ccccc7oc56)C(O)(c8cccc9c%10ccccc%10oc89)c%11cccc%12c%13ccccc%13oc%11%12 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E21 mock treatment 379360.0 -183000.0 -0.49 395740.0 -141000.0 -0.39 -0.6191 -0.993 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E22 compound treatment 213300.0 -349000.0 -0.93 525500.0 -10800.0 -0.03 -0.6808 -0.7292 3555987 CMLD3_000089 COC(=O)N[C@@H](c1cccc(C)c1)[C@@]2(CCCC2=O)C(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E23 compound treatment 640930.0 78200.0 0.21 275880.0 -260000.0 -0.71 -0.3577 -0.4803 3555990 CMLD3_000090 CC1(CC2(C)C(CC1=O)c3ccc(cc3)C(F)(F)F)C=C2/C=C/c4ccc(cc4)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 E24 mock treatment 389960.0 -173000.0 -0.46 243880.0 -292000.0 -0.8 -0.8939 -0.9654 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F01 mock treatment 402320.0 -160000.0 -0.43 757380.0 221000.0 0.61 0.1263 0.1701 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F02 mock treatment 549230.0 -13500.0 -0.04 514620.0 -21700.0 -0.06 -0.0675 -0.971 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F03 compound treatment 702480.0 140000.0 0.37 581860.0 45600.0 0.13 0.3525 0.8952 3555993 CMLD3_000091 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F04 compound treatment 613920.0 51200.0 0.14 719390.0 183000.0 0.5 0.4522 0.868 3555995 CMLD3_000092 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F05 compound treatment 328490.0 -234000.0 -0.63 257990.0 -278000.0 -0.76 -0.9826 -0.9951 3555997 CMLD3_000093 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F06 mock treatment 782660.0 220000.0 0.59 205160.0 -331000.0 -0.91 -0.2273 -0.21 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F07 compound treatment 742250.0 180000.0 0.48 701150.0 165000.0 0.45 0.6592 0.9996 3555999 CMLD3_000094 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3cc(OC)ccc3C2=O)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F08 compound treatment 330780.0 -232000.0 -0.62 318530.0 -218000.0 -0.6 -0.8607 -0.9998 3556000 CMLD3_000095 COc1ccc2O[C@@H]([C@@H](OC(=O)N[C@H]3CCCc4ccccc34)C(=O)c2c1)c5ccc(OC)c(Br)c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F09 mock treatment 501800.0 -60900.0 -0.16 483750.0 -52500.0 -0.14 -0.217 -0.9982 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F10 mock treatment 611390.0 48700.0 0.13 475110.0 -61200.0 -0.17 -0.0268 -0.126 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F11 mock treatment 530950.0 -31700.0 -0.08 242670.0 -294000.0 -0.81 -0.6299 -0.7772 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F12 compound treatment 253480.0 -309000.0 -0.83 160840.0 -375000.0 -1.03 -1.3128 -0.994 3556002 CMLD3_000096 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCc4ccco4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F13 compound treatment 282400.0 -280000.0 -0.75 279470.0 -257000.0 -0.71 -1.0279 -0.9996 3556004 CMLD3_000097 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F14 compound treatment 77120.0 -486000.0 -1.3 20530.0 -516000.0 -1.42 -1.9183 -0.999 3556006 CMLD3_000098 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(Br)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F15 compound treatment 290750.0 -272000.0 -0.73 197810.0 -338000.0 -0.93 -1.1707 -0.9926 3556008 CMLD3_000099 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(F)cc3F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F16 compound treatment 712500.0 150000.0 0.4 605450.0 69200.0 0.19 0.4172 0.942 3556010 CMLD3_000100 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccc(F)cc3F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F17 mock treatment 492040.0 -70700.0 -0.19 266740.0 -270000.0 -0.74 -0.6567 -0.8599 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F18 mock treatment 748160.0 185000.0 0.5 251840.0 -284000.0 -0.78 -0.2019 -0.2183 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F19 compound treatment 338400.0 -224000.0 -0.6 632060.0 95800.0 0.26 -0.2377 -0.3633 3556012 CMLD3_000101 COc1ccccc1/C=C/C(O)C(=C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F20 compound treatment 508660.0 -54000.0 -0.14 604810.0 68500.0 0.19 0.031 0.1307 3556014 CMLD3_000102 COCn1c2ccccc2c3nnc(nc13)C(=O)OC(C)C#C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F21 compound treatment 391200.0 -171000.0 -0.46 230990.0 -305000.0 -0.84 -0.9165 -0.9596 3556015 CMLD3_000103 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C3(CCCC3=O)C(=O)OCC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F22 compound treatment 290420.0 -272000.0 -0.73 288650.0 -248000.0 -0.68 -0.9949 -0.9994 1952239 CMLD3_000104 O=C1/C(=C/c2ccccc2)/Oc3ccccc13 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F23 compound treatment 716160.0 153000.0 0.41 560580.0 24300.0 0.07 0.337 0.8115 3556016 CMLD3_000105 Cc1c2OCOc2ccc1O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 F24 compound treatment 754560.0 192000.0 0.51 316550.0 -220000.0 -0.6 -0.0642 -0.0811 3556017 CMLD3_000106 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1ccc2ccccc2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G01 compound treatment 833680.0 271000.0 0.72 798320.0 262000.0 0.72 1.0205 1.0 3556019 CMLD3_000107 COc1ccc2O[C@H]([C@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G02 mock treatment 823470.0 261000.0 0.7 772260.0 236000.0 0.65 0.9506 0.9993 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G03 mock treatment 880960.0 318000.0 0.85 749170.0 213000.0 0.58 1.0144 0.9833 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G04 mock treatment 664390.0 102000.0 0.27 755650.0 219000.0 0.6 0.618 0.9353 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G05 compound treatment 710450.0 148000.0 0.39 515860.0 -20400.0 -0.06 0.2394 0.6007 3556020 CMLD3_000108 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G06 compound treatment 805120.0 242000.0 0.65 439040.0 -97200.0 -0.27 0.2691 0.3842 3556022 CMLD3_000109 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G07 compound treatment 743910.0 181000.0 0.48 411880.0 -124000.0 -0.34 0.1008 0.1701 3556024 CMLD3_000110 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G08 mock treatment 803010.0 240000.0 0.64 463080.0 -73200.0 -0.2 0.3118 0.4636 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G09 compound treatment 494670.0 -68000.0 -0.18 727520.0 191000.0 0.53 0.2428 0.437 3556025 CMLD3_000111 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G10 compound treatment 379130.0 -184000.0 -0.49 327720.0 -209000.0 -0.57 -0.7516 -0.997 3556027 CMLD3_000112 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G11 mock treatment 431290.0 -131000.0 -0.35 771040.0 235000.0 0.64 0.2076 0.2828 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G12 compound treatment 226440.0 -336000.0 -0.9 570780.0 34500.0 0.09 -0.5681 -0.629 3556029 CMLD3_000113 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G13 compound treatment 746080.0 183000.0 0.49 264180.0 -272000.0 -0.75 -0.1819 -0.2036 3556031 CMLD3_000114 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1Cc2cc(OC)ccc2O[C@H]1c3cccc(OC)c3)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G14 compound treatment 517210.0 -45500.0 -0.12 233140.0 -303000.0 -0.83 -0.6744 -0.8018 3556033 CMLD3_000115 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(Br)cc3)c(c1)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G15 compound treatment 225510.0 -337000.0 -0.9 257440.0 -279000.0 -0.77 -1.1781 -0.9967 3556035 CMLD3_000116 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(cc3)C(C)(C)C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G16 compound treatment 286090.0 -277000.0 -0.74 223460.0 -313000.0 -0.86 -1.1297 -0.9972 3556037 CMLD3_000117 COc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccc(F)cc3F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G17 mock treatment 672000.0 109000.0 0.29 563360.0 27100.0 0.07 0.259 0.8598 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G18 compound treatment 100560.0 -462000.0 -1.23 126950.0 -409000.0 -1.12 -1.6674 -0.9989 3556038 CMLD3_000118 CC(=C)C(O)/C=C/C=C/c1ccccc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G19 mock treatment 681800.0 119000.0 0.32 362980.0 -173000.0 -0.48 -0.1115 -0.1947 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G20 mock treatment 279840.0 -283000.0 -0.76 718500.0 182000.0 0.5 -0.1805 -0.1992 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G21 compound treatment 354030.0 -209000.0 -0.56 337170.0 -199000.0 -0.55 -0.7806 -1.0 3556040 CMLD3_000119 COC(=O)N[C@H](CC(=O)C)c1ccc(Cl)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G22 compound treatment 552060.0 -10600.0 -0.03 195000.0 -341000.0 -0.94 -0.6826 -0.7282 3556042 CMLD3_000120 CCCCCCCC1=CC2=CC(=O)C(C)(OC(=O)C)C(=O)C2=CN1CCc3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G23 compound treatment 210040.0 -353000.0 -0.94 259630.0 -277000.0 -0.76 -1.2031 -0.9943 3556043 CMLD3_000121 CCCCCCC(=O)Cc1cc(OC)c(OC)cc1C=C(C(=O)OCC)C(=O)OCC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 G24 compound treatment 505230.0 -57500.0 -0.15 215730.0 -321000.0 -0.88 -0.7308 -0.8181 3556044 CMLD3_000122 CCCCCCC(=O)Cc1cc(OC)c(OC)cc1/C=C(/C(=O)C)\C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H01 compound treatment 755530.0 193000.0 0.52 472670.0 -63600.0 -0.17 0.2407 0.4426 3556046 CMLD3_000123 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H02 compound treatment 672740.0 110000.0 0.29 511790.0 -24500.0 -0.07 0.1603 0.5317 3556048 CMLD3_000124 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H03 mock treatment 754100.0 191000.0 0.51 818800.0 283000.0 0.78 0.91 0.9795 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H04 mock treatment 795370.0 233000.0 0.62 846930.0 311000.0 0.85 1.0425 0.9879 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H05 compound treatment 313340.0 -249000.0 -0.67 652350.0 116000.0 0.32 -0.2456 -0.3326 3556050 CMLD3_000125 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H](C)C3CCCCC3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H06 compound treatment 551520.0 -11200.0 -0.03 494820.0 -41500.0 -0.11 -0.1016 -0.8633 3556052 CMLD3_000126 COC(=O)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H07 compound treatment 554800.0 -7890.0 -0.02 271550.0 -265000.0 -0.73 -0.5288 -0.7273 3556054 CMLD3_000127 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccco3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H08 compound treatment 800260.0 238000.0 0.63 254400.0 -282000.0 -0.77 -0.0985 -0.0984 3556056 CMLD3_000128 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H09 compound treatment 507240.0 -55500.0 -0.15 319860.0 -216000.0 -0.59 -0.5249 -0.8571 3556058 CMLD3_000129 Brc1ccc2O[C@H]([C@H](OC(=O)NCCOc3ccccc3)C(=O)c2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H10 compound treatment 315310.0 -247000.0 -0.66 291590.0 -245000.0 -0.67 -0.9422 -1.0 3556060 CMLD3_000130 Fc1ccc(cc1)S(=O)(=O)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H11 compound treatment 327290.0 -235000.0 -0.63 790610.0 254000.0 0.7 0.0491 0.0523 3556062 CMLD3_000131 COc1ccc2C(=O)[C@@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H12 compound treatment 317330.0 -245000.0 -0.66 466880.0 -69400.0 -0.19 -0.5981 -0.8764 3556064 CMLD3_000132 COc1ccc2C(=O)[C@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H13 mock treatment 476960.0 -85700.0 -0.23 648020.0 112000.0 0.31 0.055 0.1437 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H14 compound treatment 11170.0 -552000.0 -1.47 8340.0 -528000.0 -1.45 -2.0665 -1.0 3556065 CMLD3_000133 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(cc2)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H15 compound treatment 756320.0 194000.0 0.52 301630.0 -235000.0 -0.64 -0.0898 -0.1087 3556067 CMLD3_000134 Cc1cc(C)cc(C#C[C@H]2O[C@H](CO)[C@@H](Oc3ccc(cc3)C4CCCC4)C=C2)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H16 compound treatment 730360.0 168000.0 0.45 316670.0 -220000.0 -0.6 -0.1096 -0.146 3556069 CMLD3_000135 Cc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccc(cc3)C(C)(C)C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H17 compound treatment 266000.0 -297000.0 -0.79 380640.0 -156000.0 -0.43 -0.8625 -0.958 3556071 CMLD3_000136 CC(=O)c1ccc(cc1)[C@H]2O[C@H](CO)[C@@H](Oc3ccc(F)cc3C)C=C2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H18 compound treatment 289700.0 -273000.0 -0.73 763940.0 228000.0 0.63 -0.0736 -0.0767 3556073 CMLD3_000137 Clc1cc2nc3-c4ccccc4OC(CC=C)(c5ccccc5)c3nc2cc1Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H19 mock treatment 286720.0 -276000.0 -0.74 444030.0 -92200.0 -0.25 -0.7003 -0.8985 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H20 mock treatment 366580.0 -196000.0 -0.52 305890.0 -230000.0 -0.63 -0.8176 -0.9956 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H21 compound treatment 13140.0 -550000.0 -1.47 15200.0 -521000.0 -1.43 -2.0495 -0.9999 3556074 CMLD3_000138 CCCc1cc2C(=O)[C@H]3O[C@H]3[C@H](O)c2c(=O)o1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H22 compound treatment 266350.0 -296000.0 -0.79 249160.0 -287000.0 -0.79 -1.1171 -1.0 3556076 CMLD3_000139 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccc2ccccc2c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H23 mock treatment 604670.0 42000.0 0.11 260190.0 -276000.0 -0.76 -0.4567 -0.596 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 H24 compound treatment 502850.0 -59800.0 -0.16 317650.0 -219000.0 -0.6 -0.5374 -0.8653 3556078 CMLD3_000140 COC(=O)N[C@@H](c1cccc(F)c1)[C@@]2(CCCC2=O)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I01 compound treatment 768030.0 205000.0 0.55 857340.0 321000.0 0.88 1.0111 0.9739 3556080 CMLD3_000141 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I02 compound treatment 494940.0 -67800.0 -0.18 494580.0 -41700.0 -0.11 -0.2089 -0.9756 3556082 CMLD3_000142 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccco3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I03 compound treatment 727300.0 165000.0 0.44 774840.0 239000.0 0.65 0.774 0.9812 3555962 CMLD3_000143 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I04 mock treatment 507860.0 -54800.0 -0.15 835080.0 299000.0 0.82 0.4765 0.5718 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I05 mock treatment 209330.0 -353000.0 -0.94 822820.0 287000.0 0.79 -0.1111 -0.0904 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I06 mock treatment 744020.0 181000.0 0.48 759400.0 223000.0 0.61 0.7756 0.9932 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I07 compound treatment 646900.0 84200.0 0.22 616960.0 80700.0 0.22 0.3157 1.0 3556084 CMLD3_000144 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccc4OCOc4c3)[C@@H](Oc2c1)c5ccc6OCOc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I08 compound treatment 722400.0 160000.0 0.43 330820.0 -205000.0 -0.56 -0.0972 -0.1375 3556086 CMLD3_000145 Brc1ccc2O[C@H]([C@H](OC(=O)NC3CCCC3)C(=O)c2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I09 compound treatment 613550.0 50900.0 0.14 718490.0 182000.0 0.5 0.4498 0.8677 3556088 CMLD3_000146 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I10 compound treatment 264110.0 -299000.0 -0.8 642270.0 106000.0 0.29 -0.3582 -0.4219 3556090 CMLD3_000147 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1Cc2cc(Br)ccc2O[C@H]1c3cccc(OC)c3)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I11 compound treatment 597680.0 35000.0 0.09 614840.0 78600.0 0.22 0.2186 0.9299 3556092 CMLD3_000148 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCc4ccco4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I12 compound treatment 313610.0 -249000.0 -0.67 480750.0 -55500.0 -0.15 -0.5782 -0.8472 3556094 CMLD3_000149 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I13 compound treatment 89530.0 -473000.0 -1.26 140510.0 -396000.0 -1.09 -1.6619 -0.9972 3011535 CMLD3_000150 COCOc1cc(OC)ccc1C(=O)/C=C/c2ccc3OCOc3c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I14 compound treatment 118320.0 -444000.0 -1.19 101760.0 -435000.0 -1.19 -1.6828 -1.0 3556096 CMLD3_000151 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(C)cc2C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I15 compound treatment 209230.0 -353000.0 -0.94 180580.0 -356000.0 -0.98 -1.3581 -0.9999 3556098 CMLD3_000152 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(cc2)c3ccccc3)c4ccc(cc4)C(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I16 compound treatment 487710.0 -75000.0 -0.2 188600.0 -348000.0 -0.95 -0.8166 -0.8372 3556100 CMLD3_000153 Cc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccc(cc3)C(C)(C)C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I17 compound treatment 561760.0 -932.0 0.0 766510.0 230000.0 0.63 0.4452 0.7043 3556101 CMLD3_000154 Cc1cc(F)ccc1O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I18 compound treatment 336540.0 -226000.0 -0.6 283840.0 -252000.0 -0.69 -0.9172 -0.9977 3556103 CMLD3_000155 COC(=O)N(CCc1ccc(OC)c(OC)c1)/C=C/c2ccc(OC)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I19 compound treatment 377700.0 -185000.0 -0.49 468290.0 -68000.0 -0.19 -0.4814 -0.9114 3556105 CMLD3_000156 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)C)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I20 compound treatment 176800.0 -386000.0 -1.03 375150.0 -161000.0 -0.44 -1.0416 -0.9287 3556106 CMLD3_000157 CC(C)(C)OC1C2C3C2C(CC(O)CC=C)C1C3CC(O)CC=C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I21 mock treatment 263570.0 -299000.0 -0.8 384480.0 -152000.0 -0.42 -0.8596 -0.954 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I22 mock treatment 447070.0 -116000.0 -0.31 409860.0 -126000.0 -0.35 -0.4638 -0.9983 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I23 compound treatment 186910.0 -376000.0 -1.0 184330.0 -352000.0 -0.97 -1.393 -0.9998 2119115 CMLD3_000158 COc1ccc(/C=C/C(=O)c2ccc(OC)cc2O)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 I24 compound treatment 264100.0 -299000.0 -0.8 393500.0 -143000.0 -0.39 -0.8411 -0.9465 3556107 CMLD3_000159 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccc(Cl)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J01 compound treatment 739080.0 176000.0 0.47 363850.0 -172000.0 -0.47 -0.0016 -0.0024 3556109 CMLD3_000160 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J02 compound treatment 219620.0 -343000.0 -0.92 482810.0 -53500.0 -0.15 -0.7517 -0.81 3556112 CMLD3_000161 CCOC(=O)CNC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J03 compound treatment 786080.0 223000.0 0.6 301850.0 -234000.0 -0.64 -0.0332 -0.0378 3556115 CMLD3_000162 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4cccc(OC)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J04 mock treatment 877870.0 315000.0 0.84 449600.0 -86700.0 -0.24 0.427 0.4881 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J05 mock treatment 807750.0 245000.0 0.65 431140.0 -105000.0 -0.29 0.2587 0.3617 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J06 mock treatment 441090.0 -122000.0 -0.32 493000.0 -43300.0 -0.12 -0.3137 -0.907 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J07 compound treatment 430800.0 -132000.0 -0.35 224060.0 -312000.0 -0.86 -0.8552 -0.9228 3556117 CMLD3_000163 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCCOc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J08 compound treatment 622240.0 59500.0 0.16 403650.0 -133000.0 -0.36 -0.145 -0.3649 3556119 CMLD3_000164 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J09 compound treatment 484290.0 -78400.0 -0.21 673810.0 138000.0 0.38 0.1189 0.2754 3556123 CMLD3_000165 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J10 compound treatment 268490.0 -294000.0 -0.79 309470.0 -227000.0 -0.62 -0.9959 -0.9934 3556129 CMLD3_000166 COc1ccc2O[C@H]([C@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J11 compound treatment 209820.0 -353000.0 -0.94 206560.0 -330000.0 -0.91 -1.3065 -0.9998 3556130 CMLD3_000167 COc1ccc2O[C@@H]([C@@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J12 compound treatment 259620.0 -303000.0 -0.81 222720.0 -314000.0 -0.86 -1.1811 -0.9995 3556132 CMLD3_000168 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCc4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J13 compound treatment 3410.0 -559000.0 -1.49 9560.0 -527000.0 -1.45 -2.0788 -0.9999 3556134 CMLD3_000169 COCOc1ccc(OC)cc1C(=O)/C=C/c2ccc(OC)c(Br)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J14 compound treatment 41470.0 -521000.0 -1.39 40160.0 -496000.0 -1.36 -1.9475 -0.9999 3556136 CMLD3_000170 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(F)cc2F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J15 compound treatment 201780.0 -361000.0 -0.96 206310.0 -330000.0 -0.91 -1.3222 -0.9995 3556138 CMLD3_000171 CCOC(=O)OC[C@H]1O[C@@H]([C@@H](C=C1)c2cc(ccc2O)c3ccccc3)c4ccc(cc4)C(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J16 mock treatment 749920.0 187000.0 0.5 364270.0 -172000.0 -0.47 0.0197 0.0286 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J17 compound treatment 16360.0 -546000.0 -1.46 22560.0 -514000.0 -1.41 -2.0291 -0.9999 3556140 CMLD3_000172 COC(=O)C1(CC(=CCc2ccccc2C1C[N+](=O)[O-])C=C)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J18 mock treatment 565320.0 2630.0 0.01 306240.0 -230000.0 -0.63 -0.4416 -0.6992 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J19 compound treatment 373660.0 -189000.0 -0.5 229870.0 -306000.0 -0.84 -0.9518 -0.9702 3556141 CMLD3_000173 COc1cccc(/C=C/C(O)C(=C)C)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J20 compound treatment 712020.0 149000.0 0.4 519050.0 -17200.0 -0.05 0.2486 0.6189 3556143 CMLD3_000174 COC(=O)N1CCc2cc(OC)c(OC)cc2C1Cc3ccc(OC)cc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J21 mock treatment 420570.0 -142000.0 -0.38 240640.0 -296000.0 -0.81 -0.8423 -0.9401 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J22 mock treatment 600930.0 38200.0 0.1 440410.0 -95900.0 -0.26 -0.1139 -0.4034 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J23 compound treatment 472800.0 -89900.0 -0.24 224860.0 -311000.0 -0.85 -0.7743 -0.872 3556144 CMLD3_000175 CCOC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)OC)c2cccc(C)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 J24 compound treatment 317480.0 -245000.0 -0.65 370130.0 -166000.0 -0.46 -0.7857 -0.9844 3556146 CMLD3_000176 OC[C@@H]1CCCN1C(=O)/C=C/c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K01 compound treatment 937820.0 375000.0 1.0 877560.0 341000.0 0.94 1.371 0.9994 3556148 CMLD3_000177 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NC4CCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K02 compound treatment 831730.0 269000.0 0.72 410090.0 -126000.0 -0.35 0.2632 0.3299 3556150 CMLD3_000178 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3cccc(c3)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K03 compound treatment 296410.0 -266000.0 -0.71 803840.0 268000.0 0.73 0.0165 0.0161 3556152 CMLD3_000179 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccc4OCOc4c3)[C@@H](Oc2c1)c5cccc(c5)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K04 mock treatment 586240.0 23500.0 0.06 504690.0 -31600.0 -0.09 -0.0168 -0.1572 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K05 compound treatment 490020.0 -72700.0 -0.19 429060.0 -107000.0 -0.29 -0.3454 -0.9796 3011485 CMLD3_000180 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3cccc(c3)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K06 compound treatment 492070.0 -70600.0 -0.19 314020.0 -222000.0 -0.61 -0.5648 -0.8844 3556154 CMLD3_000181 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K07 mock treatment 828160.0 265000.0 0.71 808160.0 272000.0 0.75 1.0292 0.9997 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K08 mock treatment 797620.0 235000.0 0.63 592660.0 56400.0 0.15 0.5532 0.8559 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K09 compound treatment 314630.0 -248000.0 -0.66 578210.0 41900.0 0.12 -0.3871 -0.5756 3556156 CMLD3_000182 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K10 compound treatment 237600.0 -325000.0 -0.87 331840.0 -204000.0 -0.56 -1.0109 -0.9777 3556158 CMLD3_000183 COc1ccc2O[C@H]([C@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K11 compound treatment 456340.0 -106000.0 -0.28 302890.0 -233000.0 -0.64 -0.6539 -0.933 3556159 CMLD3_000184 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCCc4ccc(OC)c(OC)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K12 compound treatment 423530.0 -139000.0 -0.37 313830.0 -222000.0 -0.61 -0.6947 -0.9717 3556161 CMLD3_000185 COc1ccc2O[C@H]([C@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc(OC)c(Br)c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K13 mock treatment 580800.0 18100.0 0.05 764640.0 228000.0 0.63 0.4775 0.7594 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K14 compound treatment 286350.0 -276000.0 -0.74 768430.0 232000.0 0.64 -0.0712 -0.073 3556162 CMLD3_000186 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)c2cc(C)cc(C)c2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K15 mock treatment 600380.0 37700.0 0.1 694720.0 158000.0 0.44 0.3788 0.8483 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K16 mock treatment 859970.0 297000.0 0.79 462660.0 -73600.0 -0.2 0.4186 0.5108 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K17 compound treatment 279530.0 -283000.0 -0.76 184480.0 -352000.0 -0.97 -1.2177 -0.9927 3556164 CMLD3_000187 COC(=O)N[C@H](CC(=O)C)c1cccc(C)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K18 compound treatment 694450.0 132000.0 0.35 853770.0 317000.0 0.87 0.8652 0.9204 3556166 CMLD3_000188 COC(=O)N[C@H](CC(=O)C)c1ccco1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K19 compound treatment 762620.0 200000.0 0.53 488960.0 -47300.0 -0.13 0.2857 0.5199 3556168 CMLD3_000189 COc1ccc(OC)c(c1)[C@@H]2OCCC=C[C@H]2C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K20 compound treatment 605230.0 42500.0 0.11 628500.0 92200.0 0.25 0.2594 0.9346 3556170 CMLD3_000190 CC1=C(C)CC(C(C1)C(=O)c2ccccc2O)c3ccccc3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K21 mock treatment 383520.0 -179000.0 -0.48 703520.0 167000.0 0.46 -0.0137 -0.0207 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K22 compound treatment 441950.0 -121000.0 -0.32 339370.0 -197000.0 -0.54 -0.6103 -0.9695 3556171 CMLD3_000191 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)C)C(=O)OCC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K23 mock treatment 528650.0 -34000.0 -0.09 770240.0 234000.0 0.64 0.3899 0.601 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 K24 mock treatment 697180.0 134000.0 0.36 579520.0 43200.0 0.12 0.338 0.8933 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L01 mock treatment 740000.0 177000.0 0.47 521600.0 -14700.0 -0.04 0.3064 0.6446 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L02 compound treatment 465600.0 -97100.0 -0.26 446040.0 -90200.0 -0.25 -0.3585 -0.9997 3556172 CMLD3_000192 COc1ccc2O[C@H]([C@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L03 mock treatment 569370.0 6680.0 0.02 255250.0 -281000.0 -0.77 -0.5329 -0.6906 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L04 mock treatment 769410.0 207000.0 0.55 814770.0 278000.0 0.76 0.9311 0.9872 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L05 compound treatment 366560.0 -196000.0 -0.52 299170.0 -237000.0 -0.65 -0.8307 -0.9942 3556173 CMLD3_000193 O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L06 compound treatment 702450.0 140000.0 0.37 650670.0 114000.0 0.31 0.486 0.9963 3556175 CMLD3_000194 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L07 mock treatment 328040.0 -235000.0 -0.63 524900.0 -11400.0 -0.03 -0.4653 -0.7414 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L08 mock treatment 755440.0 193000.0 0.51 713760.0 177000.0 0.49 0.7086 0.9996 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L09 compound treatment 328190.0 -235000.0 -0.63 397890.0 -138000.0 -0.38 -0.7115 -0.9713 3556177 CMLD3_000195 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L10 compound treatment 398190.0 -165000.0 -0.44 279000.0 -257000.0 -0.71 -0.8101 -0.9739 3556179 CMLD3_000196 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L11 compound treatment 342830.0 -220000.0 -0.59 518270.0 -18000.0 -0.05 -0.4502 -0.7639 3556181 CMLD3_000197 COC(=O)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L12 compound treatment 348400.0 -214000.0 -0.57 313180.0 -223000.0 -0.61 -0.8378 -0.9994 3556182 CMLD3_000198 COc1ccc2C(=O)[C@H](OC(=O)NCc3ccc4OCOc4c3)[C@H](Oc2c1)c5ccc6OCOc6c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L13 compound treatment 14310.0 -548000.0 -1.46 14560.0 -522000.0 -1.43 -2.0485 -0.9999 3556183 CMLD3_000199 CCCCCCC#C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L14 compound treatment 9720.0 -553000.0 -1.48 14030.0 -522000.0 -1.43 -2.0582 -0.9999 3556185 CMLD3_000200 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(cc2)C(C)(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L15 mock treatment 378340.0 -184000.0 -0.49 690760.0 154000.0 0.42 -0.0483 -0.0743 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L16 mock treatment 318720.0 -244000.0 -0.65 430530.0 -106000.0 -0.29 -0.6661 -0.9337 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L17 compound treatment 132890.0 -430000.0 -1.15 229130.0 -307000.0 -0.84 -1.408 -0.9885 3556187 CMLD3_000201 COC(=O)CC1=CO[C@@H](O)[C@H]2[C@@H]1CC=C2CO 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L18 compound treatment 119080.0 -444000.0 -1.18 154570.0 -382000.0 -1.05 -1.5788 -0.9981 3556189 CMLD3_000202 COC(=O)C1=NOC2(C1)C=C(Br)C(=C(Br)C2=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L19 compound treatment 261390.0 -301000.0 -0.8 528210.0 -8060.0 -0.02 -0.5847 -0.7263 3556190 CMLD3_000203 O=C1OC(=NC21CC2)C3=CCCCC3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L20 mock treatment 473040.0 -89700.0 -0.24 443520.0 -92800.0 -0.25 -0.3494 -0.9995 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L21 compound treatment 740320.0 178000.0 0.47 483370.0 -52900.0 -0.15 0.2328 0.4691 3556191 CMLD3_000204 CCCCCCC1Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)OCC)C(=O)OCC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L22 compound treatment 403150.0 -160000.0 -0.43 748480.0 212000.0 0.58 0.1106 0.1533 3556192 CMLD3_000205 COC(=O)[C@@H](OCc1ccccc1)/C=C/[C@H](C)Cc2cc(Br)cc(OCc3ccccc3)c2OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L23 mock treatment 257830.0 -305000.0 -0.81 338630.0 -198000.0 -0.54 -0.9595 -0.9805 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 L24 mock treatment 256990.0 -306000.0 -0.82 521760.0 -14500.0 -0.04 -0.6055 -0.7407 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M01 mock treatment 753440.0 191000.0 0.51 500490.0 -35800.0 -0.1 0.2908 0.5604 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M02 compound treatment 484490.0 -78200.0 -0.21 805600.0 269000.0 0.74 0.3751 0.4883 3556194 CMLD3_000206 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M03 compound treatment 358910.0 -204000.0 -0.54 287650.0 -249000.0 -0.68 -0.8675 -0.9937 3556196 CMLD3_000207 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M04 compound treatment 694880.0 132000.0 0.35 768640.0 232000.0 0.64 0.7008 0.9611 3556198 CMLD3_000208 COc1ccc2C(=O)[C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M05 compound treatment 638400.0 75700.0 0.2 356210.0 -180000.0 -0.49 -0.2066 -0.3868 3556199 CMLD3_000209 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M06 compound treatment 618670.0 56000.0 0.15 246880.0 -289000.0 -0.79 -0.4561 -0.5641 3556201 CMLD3_000210 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M07 compound treatment 397690.0 -165000.0 -0.44 312880.0 -223000.0 -0.61 -0.7453 -0.9869 3556203 CMLD3_000211 COc1ccc2C(=O)[C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M08 compound treatment 568380.0 5690.0 0.02 654090.0 118000.0 0.32 0.2395 0.7395 3556205 CMLD3_000212 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(OC)cc3C2=O)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M09 mock treatment 668020.0 105000.0 0.28 546370.0 10100.0 0.03 0.2185 0.773 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M10 mock treatment 685370.0 123000.0 0.33 677520.0 141000.0 0.39 0.5059 0.9965 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M11 compound treatment 398110.0 -165000.0 -0.44 427120.0 -109000.0 -0.3 -0.5227 -0.9826 3556206 CMLD3_000213 COc1ccc2O[C@@H]([C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M12 compound treatment 466790.0 -95900.0 -0.26 618080.0 81800.0 0.22 -0.0223 -0.0655 2060493 CMLD3_000214 COc1ccc2c(=O)c(coc2c1)c3ccc4OCOc4c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M13 mock treatment 455580.0 -107000.0 -0.29 764210.0 228000.0 0.63 0.2402 0.3491 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M14 mock treatment 737720.0 175000.0 0.47 675800.0 140000.0 0.38 0.6014 0.9951 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M15 mock treatment 360490.0 -202000.0 -0.54 435800.0 -100000.0 -0.28 -0.5769 -0.9514 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M16 mock treatment 301600.0 -261000.0 -0.7 655560.0 119000.0 0.33 -0.2615 -0.3395 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M17 compound treatment 672580.0 110000.0 0.29 666080.0 130000.0 0.36 0.4595 0.9954 3556208 CMLD3_000215 COC(=O)N[C@@H](c1ccccc1)[C@@]2(CCCC2=O)C(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M18 compound treatment 648390.0 85700.0 0.23 256120.0 -280000.0 -0.77 -0.382 -0.476 3556210 CMLD3_000216 COc1ccc(/C=C/NC(=O)Cc2ccc(OC)c(OC)c2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M19 compound treatment 251710.0 -311000.0 -0.83 480350.0 -55900.0 -0.15 -0.6959 -0.8239 3556212 CMLD3_000217 CCOP(=O)(CC(C(O)c1ccccc1)C(=O)C)OCC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M20 compound treatment 222850.0 -340000.0 -0.91 270660.0 -266000.0 -0.73 -1.1575 -0.9941 3556213 CMLD3_000218 CCOC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)OC)/C=C/c2ccco2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M21 compound treatment 204480.0 -358000.0 -0.96 680230.0 144000.0 0.4 -0.3971 -0.3836 3556215 CMLD3_000219 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(O)(c4cc(cc(c4)C(F)(F)F)C(F)(F)F)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M22 compound treatment 565760.0 3070.0 0.01 482670.0 -53600.0 -0.15 -0.0983 -0.6667 3556217 CMLD3_000220 COC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)O/C=C/C)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M23 compound treatment 706750.0 144000.0 0.38 308350.0 -228000.0 -0.63 -0.1704 -0.232 3556219 CMLD3_000221 CC1(O)C(=O)C=C2C=C(CCCCOCc3ccccc3)OC=C2C1=O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 M24 compound treatment 250310.0 -312000.0 -0.83 314810.0 -221000.0 -0.61 -1.0199 -0.9879 3556220 CMLD3_000222 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N01 compound treatment 760180.0 197000.0 0.53 525290.0 -11000.0 -0.03 0.3517 0.6656 3556222 CMLD3_000223 COc1ccc2C(=O)[C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N02 mock treatment 763560.0 201000.0 0.54 555920.0 19600.0 0.05 0.4175 0.7743 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N03 compound treatment 763260.0 201000.0 0.54 783290.0 247000.0 0.68 0.8583 0.9932 3556224 CMLD3_000224 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N04 compound treatment 254610.0 -308000.0 -0.82 207960.0 -328000.0 -0.9 -1.2192 -0.999 3556226 CMLD3_000225 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3[C@H](O)[C@H]2O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N05 compound treatment 230630.0 -332000.0 -0.89 345040.0 -191000.0 -0.53 -0.9984 -0.9687 3556228 CMLD3_000226 COc1ccc2O[C@@H]([C@@H](O)C(=O)c2c1)c3ccc(OC)c(Br)c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N06 compound treatment 549940.0 -12800.0 -0.03 383540.0 -153000.0 -0.42 -0.3206 -0.762 3556229 CMLD3_000227 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(OC)cc3C2=O)c4cccc(OC)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N07 compound treatment 558240.0 -4450.0 -0.01 748680.0 212000.0 0.58 0.4039 0.6925 3556231 CMLD3_000228 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCCc4ccc(OC)c(OC)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N08 compound treatment 325760.0 -237000.0 -0.63 615490.0 79200.0 0.22 -0.2937 -0.4389 3556233 CMLD3_000229 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCCOc4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N09 mock treatment 736830.0 174000.0 0.47 814680.0 278000.0 0.76 0.8694 0.9716 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N10 mock treatment 815390.0 253000.0 0.67 641660.0 105000.0 0.29 0.6819 0.9285 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N11 mock treatment 805920.0 243000.0 0.65 706240.0 170000.0 0.47 0.7893 0.9868 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N12 compound treatment 265820.0 -297000.0 -0.79 289130.0 -247000.0 -0.68 -1.0405 -0.997 3556235 CMLD3_000230 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NCc4ccco4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N13 mock treatment 707410.0 145000.0 0.39 296960.0 -239000.0 -0.66 -0.1913 -0.2509 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N14 mock treatment 762730.0 200000.0 0.53 278350.0 -258000.0 -0.71 -0.1229 -0.1385 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N15 compound treatment 651270.0 88600.0 0.24 569400.0 33100.0 0.09 0.2316 0.9137 3556237 CMLD3_000231 CC(=O)c1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/c3ccc(Cl)cc3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N16 compound treatment 71230.0 -491000.0 -1.31 69190.0 -467000.0 -1.28 -1.835 -0.9999 3556239 CMLD3_000232 CCCCC#C[C@H]1O[C@H](CO)[C@@H](Oc2ccc(OC)cc2)C=C1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N17 compound treatment 386310.0 -176000.0 -0.47 292800.0 -243000.0 -0.67 -0.8058 -0.9853 3556241 CMLD3_000233 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1cccc(c1)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N18 compound treatment 281230.0 -281000.0 -0.75 712640.0 176000.0 0.48 -0.1892 -0.2116 3556243 CMLD3_000234 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1cccs1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N19 compound treatment 788560.0 226000.0 0.6 291740.0 -245000.0 -0.67 -0.0481 -0.0533 3556191 CMLD3_000235 CCCCCCC1Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)OCC)C(=O)OCC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N20 compound treatment 604530.0 41800.0 0.11 246180.0 -290000.0 -0.8 -0.4841 -0.602 3556245 CMLD3_000236 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)C)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N21 mock treatment 402580.0 -160000.0 -0.43 235910.0 -300000.0 -0.82 -0.8855 -0.9533 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N22 compound treatment 674100.0 111000.0 0.3 421120.0 -115000.0 -0.32 -0.0131 -0.0303 3556247 CMLD3_000237 CCC1(CC2(CC)C(CC1=O)c3ccccc3)C=C2/C=C/c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N23 compound treatment 389050.0 -174000.0 -0.46 522040.0 -14200.0 -0.04 -0.3556 -0.764 3556249 CMLD3_000238 CC1(CC2(C)C(CC1=O)c3ccc(F)cc3)C=C2/C=C/c4ccc(F)cc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 N24 mock treatment 808770.0 246000.0 0.66 827100.0 291000.0 0.8 1.0293 0.9953 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O01 compound treatment 452960.0 -110000.0 -0.29 606290.0 70000.0 0.19 -0.0713 -0.2035 3556251 CMLD3_000239 COc1ccc2O[C@@H]([C@@H](OC(=O)N[C@H](C)C3CCCCC3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O02 compound treatment 757020.0 194000.0 0.52 761600.0 225000.0 0.62 0.8045 0.9962 3556253 CMLD3_000240 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O03 compound treatment 668660.0 106000.0 0.28 712610.0 176000.0 0.48 0.5425 0.9673 3556254 CMLD3_000241 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@@H](Oc2c1)c5cccc(c5)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O04 compound treatment 569280.0 6590.0 0.02 528720.0 -7550.0 -0.02 -0.0022 -0.0817 3556256 CMLD3_000242 COc1ccc2C(=O)[C@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O05 compound treatment 244040.0 -319000.0 -0.85 303240.0 -233000.0 -0.64 -1.0542 -0.9901 3131449 CMLD3_000243 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O06 compound treatment 575230.0 12500.0 0.03 215080.0 -321000.0 -0.88 -0.5999 -0.6798 3556257 CMLD3_000244 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O07 mock treatment 605280.0 42600.0 0.11 532480.0 -3790.0 -0.01 0.0731 0.6397 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O08 mock treatment 697000.0 134000.0 0.36 395550.0 -141000.0 -0.39 -0.0195 -0.037 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O09 mock treatment 522530.0 -40200.0 -0.11 538050.0 1780.0 0.0 -0.0724 -0.6743 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O10 compound treatment 623290.0 60600.0 0.16 587940.0 51700.0 0.14 0.2148 0.9978 3556259 CMLD3_000245 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O11 mock treatment 596000.0 33300.0 0.09 437310.0 -99000.0 -0.27 -0.1292 -0.452 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O12 mock treatment 528250.0 -34400.0 -0.09 534660.0 -1610.0 0.0 -0.0682 -0.7403 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O13 compound treatment 118410.0 -444000.0 -1.19 105650.0 -431000.0 -1.18 -1.6751 -1.0 3556261 CMLD3_000246 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O14 compound treatment 98010.0 -465000.0 -1.24 96370.0 -440000.0 -1.21 -1.7316 -0.9999 3556263 CMLD3_000247 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(C)cc2C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O15 compound treatment 429320.0 -133000.0 -0.36 347470.0 -189000.0 -0.52 -0.6184 -0.9833 3556265 CMLD3_000248 CC(=O)c1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/c3ccc(Cl)cc3)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O16 compound treatment 58970.0 -504000.0 -1.35 47200.0 -489000.0 -1.34 -1.9008 -1.0 3556008 CMLD3_000249 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(F)cc3F)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O17 compound treatment 364440.0 -198000.0 -0.53 307080.0 -229000.0 -0.63 -0.8194 -0.9963 3556266 CMLD3_000250 CC(=CCC1(CC=C(C)C)C(=O)C(=C2OC(C)(C)CCC2(CC=C(C)C)C1=O)C(=O)c3ccccc3)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O18 compound treatment 287700.0 -275000.0 -0.73 297760.0 -239000.0 -0.65 -0.9824 -0.9984 3556267 CMLD3_000251 CC1(CC2(C)C(CC1=O)/C=C/c3ccccc3)C=C2/C=C/C=C/c4ccccc4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O19 compound treatment 343200.0 -219000.0 -0.59 367590.0 -169000.0 -0.46 -0.742 -0.9932 1125649 CMLD3_000252 CNc1ccccc1C(=O)OCC(=O)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O20 mock treatment 316190.0 -247000.0 -0.66 282590.0 -254000.0 -0.7 -0.958 -0.9996 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O21 mock treatment 452480.0 -110000.0 -0.29 434770.0 -102000.0 -0.28 -0.4052 -0.9996 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O22 compound treatment 278920.0 -284000.0 -0.76 326130.0 -210000.0 -0.58 -0.9439 -0.9909 3556269 CMLD3_000253 CNc1ccccc1C(=O)OCC(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O23 compound treatment 272400.0 -290000.0 -0.78 343840.0 -192000.0 -0.53 -0.9218 -0.9825 3556270 CMLD3_000254 COc1ccc(/C=C/NC(=O)c2ccc(OC)cc2)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 O24 compound treatment 336800.0 -226000.0 -0.6 353290.0 -183000.0 -0.5 -0.7819 -0.9959 3556272 CMLD3_000255 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2ccc(Cl)cc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P01 compound treatment 248060.0 -315000.0 -0.84 526610.0 -9660.0 -0.03 -0.613 -0.7291 3556274 CMLD3_000256 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3cccc(c3)C(F)(F)F)C(C)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P02 mock treatment 214900.0 -348000.0 -0.93 442720.0 -93600.0 -0.26 -0.8385 -0.87 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P03 mock treatment 260020.0 -303000.0 -0.81 479960.0 -56300.0 -0.15 -0.681 -0.8273 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P04 compound treatment 212130.0 -351000.0 -0.94 370520.0 -166000.0 -0.46 -0.9839 -0.9451 3556276 CMLD3_000257 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3ccc(C)c(Br)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P05 compound treatment 353450.0 -209000.0 -0.56 217030.0 -319000.0 -0.88 -1.0149 -0.9764 3011477 CMLD3_000258 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2O 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P06 compound treatment 347110.0 -216000.0 -0.58 315010.0 -221000.0 -0.61 -0.8367 -0.9996 3556277 CMLD3_000259 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3cccc(OC)c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P07 compound treatment 482480.0 -80200.0 -0.21 414130.0 -122000.0 -0.34 -0.3886 -0.9766 3556279 CMLD3_000260 COc1ccc2O[C@H]([C@H](OC(=O)NCCc3ccc(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P08 compound treatment 318320.0 -244000.0 -0.65 313540.0 -223000.0 -0.61 -0.8939 -0.9995 3556280 CMLD3_000261 COc1ccc2C(=O)[C@@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P09 mock treatment 373190.0 -190000.0 -0.51 444960.0 -91300.0 -0.25 -0.5352 -0.9475 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P10 compound treatment 383730.0 -179000.0 -0.48 387740.0 -149000.0 -0.41 -0.6263 -0.9969 3556282 CMLD3_000262 COc1ccc2C(=O)[C@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P11 mock treatment 484270.0 -78400.0 -0.21 397230.0 -139000.0 -0.38 -0.418 -0.9601 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P12 mock treatment 348970.0 -214000.0 -0.57 318400.0 -218000.0 -0.6 -0.8266 -0.9997 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P13 compound treatment 314780.0 -248000.0 -0.66 307740.0 -229000.0 -0.63 -0.9119 -0.9996 3556284 CMLD3_000263 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)c2ccccc2 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P14 compound treatment 72750.0 -490000.0 -1.31 79040.0 -457000.0 -1.26 -1.813 -0.9998 3556286 CMLD3_000264 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(F)cc2F 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P15 compound treatment 576210.0 13500.0 0.04 556480.0 20200.0 0.06 0.0648 0.9784 3556288 CMLD3_000265 Cc1cc(C)cc(/C=C/[C@@H]2OC[C@@H](O)[C@H]2Oc3ccc(cc3)C4CCCC4)c1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P16 compound treatment 252860.0 -310000.0 -0.83 367210.0 -169000.0 -0.46 -0.9134 -0.9626 3556289 CMLD3_000266 Cc1cc(F)ccc1O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccc4OCOc4c3 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P17 compound treatment 173700.0 -389000.0 -1.04 444160.0 -92100.0 -0.25 -0.9135 -0.8543 3556073 CMLD3_000267 Clc1cc2nc3-c4ccccc4OC(CC=C)(c5ccccc5)c3nc2cc1Cl 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P18 compound treatment 339360.0 -223000.0 -0.6 205050.0 -331000.0 -0.91 -1.0648 -0.9791 3556291 CMLD3_000268 COc1ccc(cc1)C(=O)Oc2cc(OC)cc(OC)c2C(=O)C 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P19 compound treatment 311040.0 -252000.0 -0.67 296000.0 -240000.0 -0.66 -0.9417 -1.0 3556292 CMLD3_000269 CC(=C)C(O)/C=C/c1ccc(Br)cc1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P20 mock treatment 339450.0 -223000.0 -0.6 243370.0 -293000.0 -0.8 -0.9902 -0.9892 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P21 compound treatment 232280.0 -330000.0 -0.88 131380.0 -405000.0 -1.11 -1.4101 -0.9935 3556294 CMLD3_000270 COC(=O)N[C@@H](/C=C/c1ccco1)[C@@]2(CCCC2=O)C(=O)OC 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P22 compound treatment 398600.0 -164000.0 -0.44 209400.0 -327000.0 -0.9 -0.9445 -0.9457 3556296 CMLD3_000271 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cc(F)c(F)c(F)c2)c3cc(F)c(F)c(F)c3)C(O)(c4cc(F)c(F)c(F)c4)c5cc(F)c(F)c(F)c5 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P23 compound treatment 289930.0 -273000.0 -0.73 307370.0 -229000.0 -0.63 -0.9595 -0.9973 3556298 CMLD3_000272 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccco1 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.2284 P24 mock treatment 262990.0 -300000.0 -0.8 326210.0 -210000.0 -0.58 -0.9738 -0.9871 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A01 mock treatment 814330.0 199000.0 0.53 776130.0 81100.0 0.22 0.947 0.9557 790000.0 241968.307291667 0.560470072039365 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A02 mock treatment 855360.0 240000.0 0.64 856720.0 162000.0 0.44 0.5025 0.481 319320.0 -228711.692708333 -0.529763836939066 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A03 mock treatment 801880.0 187000.0 0.5 890180.0 195000.0 0.54 0.1068 0.1096 285920.0 -262111.692708333 -0.607128102597007 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A04 mock treatment 161320.0 -454000.0 -1.21 848080.0 153000.0 0.42 0.2225 0.1433 815300.0 267268.307291667 0.619072345127565 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A05 mock treatment 617330.0 2200.0 0.01 569280.0 -126000.0 -0.35 -0.7093 -0.8131 389450.0 -158581.692708333 -0.36732204201118 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A06 mock treatment 174560.0 -441000.0 -1.18 369500.0 -326000.0 -0.89 -1.2421 -0.7257 706830.0 158798.307291667 0.367823785369576 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A07 mock treatment 755890.0 141000.0 0.38 485320.0 -210000.0 -0.58 -0.6959 -0.6397 289400.0 -258631.692708333 -0.599067394678156 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A08 mock treatment 581540.0 -33600.0 -0.09 960900.0 266000.0 0.73 -0.0511 -0.0544 308430.0 -239601.692708333 -0.554988293616161 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A09 mock treatment 803840.0 189000.0 0.5 348520.0 -347000.0 -0.95 0.0321 0.0253 486090.0 -61941.692708333 -0.143475256586527 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A10 mock treatment 717160.0 102000.0 0.27 918920.0 224000.0 0.61 -0.0136 -0.0145 388320.0 -159711.692708333 -0.369939455789428 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A11 mock treatment 536370.0 -78800.0 -0.21 953720.0 259000.0 0.71 -0.0017 -0.0018 589230.0 41198.307291667 0.0954274488014971 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A12 mock treatment 741300.0 126000.0 0.34 246840.0 -448000.0 -1.23 -0.5818 -0.3932 711040.0 163008.307291667 0.377575388915083 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A13 mock treatment 310990.0 -304000.0 -0.81 225320.0 -470000.0 -1.29 -1.4541 -0.883 296850.0 -251181.692708333 -0.581810994104753 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A14 mock treatment 902730.0 288000.0 0.77 899750.0 205000.0 0.56 0.7837 0.7268 453290.0 -94741.692708333 -0.21944974501708 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A15 mock treatment 734810.0 120000.0 0.32 423270.0 -272000.0 -0.75 -0.4118 -0.4746 499520.0 -48511.692708333 -0.112367409646822 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A16 mock treatment 298950.0 -316000.0 -0.84 757810.0 62700.0 0.17 -0.5763 -0.5807 553070.0 5038.30729166698 0.0116702078975708 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A17 mock treatment 335380.0 -280000.0 -0.75 242910.0 -452000.0 -1.24 -1.1031 -0.757 495560.0 -52471.692708333 -0.121539939347584 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A18 mock treatment 326910.0 -288000.0 -0.77 832830.0 138000.0 0.38 0.0775 0.0699 486750.0 -61281.692708333 -0.1419465016364 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A19 mock treatment 305390.0 -310000.0 -0.83 808480.0 113000.0 0.31 0.0351 0.032 521800.0 -26231.692708333 -0.0607603486031421 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A20 mock treatment 597470.0 -17700.0 -0.05 738410.0 43300.0 0.12 0.272 0.3701 845930.0 297898.307291667 0.690020472585731 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A21 mock treatment 716520.0 101000.0 0.27 551490.0 -144000.0 -0.39 -0.1967 -0.3391 571200.0 23168.307291667 0.053664643118483 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A22 mock treatment 599360.0 -15800.0 -0.04 363050.0 -332000.0 -0.91 -0.5441 -0.5801 459450.0 -88581.692708333 -0.205181365482562 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A23 mock treatment 509640.0 -105000.0 -0.28 490210.0 -205000.0 -0.56 -0.2681 -0.401 594980.0 46948.307291667 0.108746147230634 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base A24 mock treatment 588450.0 -26700.0 -0.07 555280.0 -140000.0 -0.38 -0.6333 -0.8091 262340.0 -285691.692708333 -0.661746347633361 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B01 mock treatment 514250.0 -101000.0 -0.27 713360.0 18300.0 0.05 0.5777 0.5624 787520.0 239488.307291667 0.554725659499494 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B02 mock treatment 389340.0 -226000.0 -0.6 915480.0 220000.0 0.61 0.8024 0.5654 889970.0 341938.307291667 0.792030121076022 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B03 mock treatment 737240.0 122000.0 0.33 440040.0 -255000.0 -0.7 0.4641 0.3845 863000.0 314968.307291667 0.729559634704924 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B04 mock treatment 891590.0 276000.0 0.74 956440.0 261000.0 0.72 0.9338 0.7068 873510.0 325478.307291667 0.753903899138007 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B05 mock treatment 833000.0 218000.0 0.58 807540.0 112000.0 0.31 0.4669 0.4583 794280.0 246248.307291667 0.5703838162614 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B06 mock treatment 326370.0 -289000.0 -0.77 389670.0 -305000.0 -0.84 -0.1364 -0.0918 802350.0 254318.307291667 0.589076319969771 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B07 mock treatment 304560.0 -311000.0 -0.83 957390.0 262000.0 0.72 -0.1423 -0.1094 300430.0 -247601.692708333 -0.573518656648003 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B08 mock treatment 830240.0 215000.0 0.57 840640.0 146000.0 0.4 1.0104 0.979 824760.0 276728.307291667 0.640984499412719 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B09 mock treatment 675070.0 59900.0 0.16 525090.0 -170000.0 -0.47 0.1105 0.1724 610930.0 62898.307291667 0.145691058525369 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B10 mock treatment 471890.0 -143000.0 -0.38 957460.0 262000.0 0.72 0.3066 0.2936 417570.0 -130461.692708333 -0.302187815954255 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B11 mock treatment 440280.0 -175000.0 -0.47 903330.0 208000.0 0.57 0.5931 0.5574 796160.0 248128.307291667 0.574738451573883 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B12 mock treatment 772480.0 157000.0 0.42 704880.0 9810.0 0.03 0.3809 0.6439 723010.0 174978.307291667 0.405301444601477 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B13 mock treatment 809550.0 194000.0 0.52 588650.0 -106000.0 -0.29 -0.1349 -0.1826 361280.0 -186751.692708333 -0.432572082837054 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B14 mock treatment 641800.0 26700.0 0.07 870560.0 175000.0 0.48 0.245 0.3348 700660.0 152628.307291667 0.353532242881268 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B15 mock treatment 392500.0 -223000.0 -0.59 887700.0 193000.0 0.53 0.2657 0.2939 699960.0 151928.307291667 0.351910836115982 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B16 mock treatment 482770.0 -132000.0 -0.35 691580.0 -3490.0 -0.01 0.0581 0.0934 768480.0 220448.307291667 0.51062339548371 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B17 mock treatment 435070.0 -180000.0 -0.48 898890.0 204000.0 0.56 0.4771 0.4822 806120.0 258088.307291667 0.597808753548527 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B18 mock treatment 810410.0 195000.0 0.52 879250.0 184000.0 0.51 0.1084 0.1045 516180.0 -31851.692708333 -0.0737779286330112 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B19 mock treatment 776670.0 162000.0 0.43 793710.0 98600.0 0.27 0.2975 0.3238 757220.0 209188.307291667 0.484541909516392 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B20 mock treatment 751290.0 136000.0 0.36 594130.0 -101000.0 -0.28 0.0118 0.0197 416090.0 -131941.692708333 -0.305615933115146 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B21 mock treatment 389920.0 -225000.0 -0.6 987810.0 293000.0 0.8 0.4369 0.3877 751360.0 203328.307291667 0.470968418595567 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B22 mock treatment 373780.0 -241000.0 -0.64 848320.0 153000.0 0.42 0.4428 0.4017 761920.0 213888.307291667 0.495428497797599 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B23 mock treatment 848120.0 233000.0 0.62 829550.0 134000.0 0.37 0.0678 0.0718 369760.0 -178271.692708333 -0.412929898023301 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base B24 mock treatment 698260.0 83100.0 0.22 596080.0 -99000.0 -0.27 -0.3884 -0.5779 468480.0 -79551.692708333 -0.18426521821037 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C01 mock treatment 516800.0 -98300.0 -0.26 824220.0 129000.0 0.35 0.4071 0.6018 717550.0 169518.307291667 0.392654471832245 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C02 mock treatment 338510.0 -277000.0 -0.74 866250.0 171000.0 0.47 -0.0413 -0.038 780960.0 232928.307291667 0.539530761813383 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C03 mock treatment 563720.0 -51400.0 -0.14 793510.0 98400.0 0.27 0.4001 0.6848 642030.0 93998.307291667 0.217727844811655 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C04 mock treatment 428170.0 -187000.0 -0.5 603110.0 -92000.0 -0.25 -0.2254 -0.3758 624070.0 76038.307291667 0.17612717980517 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C05 mock treatment 703110.0 88000.0 0.24 841320.0 146000.0 0.4 0.1124 0.1193 692960.0 144928.307291667 0.33569676846312 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C06 mock treatment 696550.0 81400.0 0.22 795370.0 100000.0 0.28 0.6088 0.9794 696580.0 148548.307291667 0.344081757735029 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C07 mock treatment 770730.0 156000.0 0.42 531930.0 -163000.0 -0.45 -0.0697 -0.0744 740480.0 192448.307291667 0.445767124872262 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C08 mock treatment 421000.0 -194000.0 -0.52 862240.0 167000.0 0.46 0.4037 0.4362 745760.0 197728.307291667 0.457997164473278 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C09 mock treatment 735100.0 120000.0 0.32 544600.0 -150000.0 -0.41 0.211 0.3312 656000.0 107968.307291667 0.250086491256009 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C10 mock treatment 620320.0 5190.0 0.01 771740.0 76700.0 0.21 0.1412 0.2797 700090.0 152058.307291667 0.352211954515249 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C11 mock treatment 696410.0 81300.0 0.22 529600.0 -165000.0 -0.45 0.1742 0.2387 774720.0 226688.307291667 0.525077078648546 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C12 mock treatment 498920.0 -116000.0 -0.31 634740.0 -60300.0 -0.17 -0.3296 -0.7901 564320.0 16288.307291667 0.0377285309110988 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C13 mock treatment 435200.0 -180000.0 -0.48 889440.0 194000.0 0.53 0.1725 0.23 591110.0 43078.307291667 0.09978208411398 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C14 mock treatment 795120.0 180000.0 0.48 614020.0 -81100.0 -0.22 -0.318 -0.351 240690.0 -307341.692708333 -0.711894142588284 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C15 mock treatment 508390.0 -107000.0 -0.29 356550.0 -339000.0 -0.93 -1.1117 -0.8825 441570.0 -106461.692708333 -0.246596726858729 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C16 mock treatment 730720.0 116000.0 0.31 703400.0 8330.0 0.02 0.1031 0.2333 428670.0 -119361.692708333 -0.276476937247574 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C17 mock treatment 385970.0 -229000.0 -0.61 581120.0 -114000.0 -0.31 -0.7776 -0.8768 308290.0 -239741.692708333 -0.555312574969218 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C18 mock treatment 776640.0 162000.0 0.43 617480.0 -77600.0 -0.21 0.2345 0.427 542150.0 -5881.69270833302 -0.0136237376408937 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C19 mock treatment 709210.0 94100.0 0.25 593120.0 -102000.0 -0.28 -0.1964 -0.2474 271040.0 -276991.692708333 -0.641594577836233 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C20 mock treatment 738780.0 124000.0 0.33 684560.0 -10500.0 -0.03 0.3455 0.7842 604320.0 56288.307291667 0.130380346070309 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C21 mock treatment 772000.0 157000.0 0.42 503310.0 -192000.0 -0.53 -0.4043 -0.4766 352560.0 -195471.692708333 -0.452770178541762 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C22 mock treatment 352480.0 -263000.0 -0.7 609060.0 -86000.0 -0.24 -0.6973 -0.8199 368040.0 -179991.692708333 -0.416913926075148 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C23 mock treatment 253210.0 -362000.0 -0.97 615360.0 -79700.0 -0.22 -1.0085 -0.8468 460320.0 -87711.692708333 -0.203166188502849 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base C24 mock treatment 628160.0 13000.0 0.03 748420.0 53300.0 0.15 -0.5539 -0.5981 289560.0 -258471.692708333 -0.598696787417519 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D01 mock treatment 827170.0 212000.0 0.57 805300.0 110000.0 0.3 0.952 0.9734 743390.0 195358.307291667 0.452507544425095 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D02 mock treatment 743710.0 129000.0 0.34 872380.0 177000.0 0.49 0.7634 0.9703 653700.0 105668.307291667 0.244759011884355 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D03 mock treatment 830030.0 215000.0 0.57 696290.0 1220.0 0.0 0.6811 0.8427 679150.0 131118.307291667 0.303708729279403 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D04 mock treatment 780580.0 165000.0 0.44 752530.0 57500.0 0.16 0.7251 0.897 649950.0 101918.307291667 0.236072904213179 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D05 mock treatment 354500.0 -261000.0 -0.7 883310.0 188000.0 0.52 0.3653 0.3336 688640.0 140608.307291667 0.325690372425925 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D06 mock treatment 607320.0 -7810.0 -0.02 854880.0 160000.0 0.44 0.6168 0.8289 775360.0 227328.307291667 0.526559507691094 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D07 mock treatment 828770.0 214000.0 0.57 903680.0 209000.0 0.57 0.945 0.9774 694030.0 145998.307291667 0.338175204518629 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D08 mock treatment 490420.0 -125000.0 -0.33 870240.0 175000.0 0.48 0.3775 0.5155 709210.0 161178.307291667 0.373336568371549 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D09 mock treatment 554980.0 -60100.0 -0.16 444730.0 -250000.0 -0.69 0.0058 0.0061 666050.0 118018.307291667 0.273365259814761 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D10 mock treatment 846370.0 231000.0 0.62 900800.0 206000.0 0.56 1.0548 0.9878 778640.0 230608.307291667 0.534156956534149 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D11 mock treatment 794240.0 179000.0 0.48 877670.0 183000.0 0.5 0.564 0.4971 852350.0 304318.307291667 0.704891088918784 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D12 mock treatment 603010.0 -12100.0 -0.03 634080.0 -61000.0 -0.17 0.1716 0.3459 584690.0 36658.307291667 0.0849114677809267 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D13 mock treatment 491300.0 -124000.0 -0.33 954750.0 260000.0 0.71 -0.4423 -0.3709 286780.0 -261251.692708333 -0.605136088571084 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D14 mock treatment 781330.0 166000.0 0.44 714720.0 19600.0 0.05 0.6615 0.8922 755550.0 207518.307291667 0.480673696233495 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D15 mock treatment 780210.0 165000.0 0.44 664770.0 -30300.0 -0.08 0.4209 0.7427 668320.0 120288.307291667 0.278623250325046 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D16 mock treatment 545760.0 -69400.0 -0.19 758780.0 63700.0 0.17 0.3148 0.4068 861340.0 313308.307291667 0.725714584375817 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D17 mock treatment 744280.0 129000.0 0.34 840040.0 145000.0 0.4 0.2992 0.4503 636520.0 88488.307291667 0.204965057273474 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D18 mock treatment 691860.0 76700.0 0.2 798510.0 103000.0 0.28 -0.1473 -0.2232 355050.0 -192981.692708333 -0.447002603048101 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D19 mock treatment 442300.0 -173000.0 -0.46 748720.0 53600.0 0.15 -0.1001 -0.2034 582600.0 34568.307291667 0.080070410438858 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D20 mock treatment 545670.0 -69500.0 -0.19 662970.0 -32100.0 -0.09 -0.7565 -0.8259 228660.0 -319371.692708333 -0.739759175997417 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D21 mock treatment 489870.0 -125000.0 -0.33 844180.0 149000.0 0.41 -0.0362 -0.0412 727690.0 179658.307291667 0.416141706975105 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D22 mock treatment 338000.0 -277000.0 -0.74 429630.0 -265000.0 -0.73 -0.6916 -0.6647 569600.0 21568.307291667 0.0499585705121146 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D23 mock treatment 675300.0 60200.0 0.16 586240.0 -109000.0 -0.3 -0.6584 -0.7116 227890.0 -320141.692708333 -0.741542723439232 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base D24 mock treatment 372640.0 -242000.0 -0.65 463680.0 -231000.0 -0.64 -1.1069 -0.9522 252930.0 -295101.692708333 -0.683542687149566 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E01 mock treatment 773240.0 158000.0 0.42 768980.0 73900.0 0.2 0.269 0.2671 257700.0 -290331.692708333 -0.67249395819183 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E02 mock treatment 823360.0 208000.0 0.56 925920.0 231000.0 0.63 0.4571 0.3882 732210.0 184178.307291667 0.426611362088095 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E03 mock treatment 868270.0 253000.0 0.68 644680.0 -50400.0 -0.14 0.9416 0.7973 803090.0 255058.307291667 0.590790378550216 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E04 mock treatment 879880.0 265000.0 0.71 794480.0 99400.0 0.27 0.3618 0.4642 490450.0 -57581.692708333 -0.133376208734173 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E05 mock treatment 740550.0 125000.0 0.34 861440.0 166000.0 0.46 0.7984 0.9942 723730.0 175698.307291667 0.406969177274343 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E06 mock treatment 479890.0 -135000.0 -0.36 971580.0 277000.0 0.76 0.6644 0.6194 780160.0 232128.307291667 0.537677725510199 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E07 mock treatment 840320.0 225000.0 0.6 690160.0 -4910.0 -0.01 0.8601 0.8555 819640.0 271608.307291667 0.62912506707234 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E08 mock treatment 444840.0 -170000.0 -0.45 793780.0 98700.0 0.27 0.3005 0.3904 737030.0 188998.307291667 0.43777590581478 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E09 mock treatment 488590.0 -127000.0 -0.34 723720.0 28600.0 0.08 0.0615 0.0981 494280.0 -53751.692708333 -0.124504797432679 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E10 mock treatment 769770.0 155000.0 0.41 802930.0 108000.0 0.3 0.1232 0.1966 397620.0 -150411.692708333 -0.348397908764911 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E11 mock treatment 456800.0 -158000.0 -0.42 806450.0 111000.0 0.31 0.3722 0.4556 781130.0 233098.307291667 0.53992453202781 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E12 mock treatment 908090.0 293000.0 0.78 740640.0 45600.0 0.13 0.8042 0.7318 875840.0 327808.307291667 0.759300867371031 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E13 mock treatment 805230.0 190000.0 0.51 1006760.0 312000.0 0.86 0.4092 0.3297 236720.0 -311311.692708333 -0.721089835242836 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E14 mock treatment 811400.0 196000.0 0.52 609610.0 -85500.0 -0.23 -0.2474 -0.2804 264200.0 -283831.692708333 -0.657438038228458 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E15 mock treatment 799060.0 184000.0 0.49 692920.0 -2150.0 -0.01 0.4898 0.8076 674830.0 126798.307291667 0.293702333242208 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E16 mock treatment 905660.0 291000.0 0.78 616160.0 -78900.0 -0.22 0.2927 0.3525 492370.0 -55661.692708333 -0.128928921606531 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E17 mock treatment 592590.0 -22500.0 -0.06 935200.0 240000.0 0.66 0.1411 0.2015 491060.0 -56971.692708333 -0.131963268552995 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E18 mock treatment 491130.0 -124000.0 -0.33 865290.0 170000.0 0.47 0.0652 0.0961 435780.0 -112251.692708333 -0.260008077103024 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E19 mock treatment 719850.0 105000.0 0.28 938340.0 243000.0 0.67 0.3544 0.3996 348910.0 -199121.692708333 -0.46122465667504 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E20 mock treatment 420120.0 -195000.0 -0.52 686280.0 -8790.0 -0.02 -0.8881 -0.872 255920.0 -292111.692708333 -0.676616963966415 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E21 mock treatment 733860.0 119000.0 0.32 814620.0 120000.0 0.33 -0.1713 -0.2052 329450.0 -218581.692708333 -0.506299764749996 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E22 mock treatment 670770.0 55600.0 0.15 603680.0 -91400.0 -0.25 -0.6468 -0.7139 241400.0 -306631.692708333 -0.710249572869208 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E23 mock treatment 714570.0 99400.0 0.27 543570.0 -152000.0 -0.42 -0.4401 -0.6071 352190.0 -195841.692708333 -0.453627207831985 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base E24 mock treatment 407760.0 -207000.0 -0.55 504800.0 -190000.0 -0.52 -1.257 -0.983 283080.0 -264951.692708333 -0.613706381473311 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F01 mock treatment 433830.0 -181000.0 -0.48 528990.0 -166000.0 -0.46 -0.4291 -0.5273 423720.0 -124311.692708333 -0.287942599373526 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F02 mock treatment 809700.0 195000.0 0.52 748080.0 53000.0 0.15 0.0669 0.1013 452540.0 -95491.692708333 -0.221186966551315 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F03 mock treatment 534400.0 -80700.0 -0.22 622250.0 -72800.0 -0.2 -0.1215 -0.1657 383680.0 -164351.692708333 -0.380687066347896 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F04 mock treatment 523600.0 -91500.0 -0.24 490760.0 -204000.0 -0.56 -0.9909 -0.9573 315970.0 -232061.692708333 -0.53752342645865 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F05 mock treatment 609720.0 -5410.0 -0.01 455560.0 -240000.0 -0.66 -0.7765 -0.7779 485800.0 -62231.692708333 -0.144146982246432 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F06 mock treatment 499630.0 -115000.0 -0.31 555370.0 -140000.0 -0.38 -0.3625 -0.3696 799810.0 251778.307291667 0.583192929707161 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F07 mock treatment 867600.0 252000.0 0.67 613120.0 -82000.0 -0.22 -0.2155 -0.2191 441600.0 -106431.692708333 -0.246527237997359 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F08 mock treatment 786560.0 171000.0 0.46 801170.0 106000.0 0.29 0.6598 0.8113 809080.0 261048.307291667 0.604664987870308 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F09 mock treatment 679630.0 64500.0 0.17 490530.0 -205000.0 -0.56 -0.5203 -0.6908 438180.0 -109851.692708333 -0.254448968193472 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F10 mock treatment 896490.0 281000.0 0.75 651360.0 -43700.0 -0.12 0.7564 0.7452 814800.0 266768.307291667 0.617914197438075 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F11 mock treatment 776290.0 161000.0 0.43 596560.0 -98500.0 -0.27 0.1113 0.1794 453920.0 -94111.692708333 -0.217990478928322 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F12 mock treatment 357120.0 -258000.0 -0.69 586090.0 -109000.0 -0.3 -1.1394 -0.9485 334830.0 -213201.692708333 -0.493838095611082 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F13 mock treatment 457490.0 -158000.0 -0.42 721930.0 26900.0 0.07 0.0045 0.0056 814000.0 265968.307291667 0.616061161134891 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F14 mock treatment 453860.0 -161000.0 -0.43 760010.0 64900.0 0.18 0.3385 0.3678 884340.0 336308.307291667 0.778989378092363 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F15 mock treatment 729220.0 114000.0 0.3 988880.0 294000.0 0.81 0.728 0.743 501400.0 -46631.692708333 -0.108012774334339 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F16 mock treatment 607760.0 -7370.0 -0.02 845540.0 150000.0 0.41 0.7532 0.8311 734530.0 186498.307291667 0.43198516736733 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F17 mock treatment 357890.0 -257000.0 -0.69 607910.0 -87200.0 -0.24 -0.7489 -0.6905 212370.0 -335661.692708333 -0.777491627721005 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F18 mock treatment 738520.0 123000.0 0.33 934560.0 239000.0 0.66 -0.2615 -0.201 253630.0 -294401.692708333 -0.68192128038428 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F19 mock treatment 381350.0 -234000.0 -0.62 642240.0 -52800.0 -0.15 -0.5816 -0.7165 337060.0 -210971.692708333 -0.488672756915956 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F20 mock treatment 597210.0 -17900.0 -0.05 845930.0 151000.0 0.41 -0.2719 -0.3102 481120.0 -66911.692708333 -0.154987244620059 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F21 mock treatment 374950.0 -240000.0 -0.64 421320.0 -274000.0 -0.75 -0.4215 -0.3925 618010.0 69978.307291667 0.162090429808549 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F22 mock treatment 379400.0 -236000.0 -0.63 579430.0 -116000.0 -0.32 -0.693 -0.7197 276970.0 -271061.692708333 -0.62785894623888 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F23 mock treatment 416440.0 -199000.0 -0.53 526530.0 -169000.0 -0.46 -0.6704 -0.8888 438330.0 -109701.692708333 -0.254101523886625 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base F24 mock treatment 344260.0 -271000.0 -0.72 646050.0 -49000.0 -0.13 -0.5306 -0.513 721700.0 173668.307291667 0.402267097655013 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G01 mock treatment 616650.0 1520.0 0.0 906610.0 212000.0 0.58 0.914 0.8604 857830.0 309798.307291667 0.717584387595596 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G02 mock treatment 557190.0 -57900.0 -0.15 1037780.0 343000.0 0.94 0.3225 0.3117 398740.0 -149291.692708333 -0.345803657940453 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G03 mock treatment 901360.0 286000.0 0.76 993760.0 299000.0 0.82 1.3154 0.9436 660100.0 112068.307291667 0.259583302309828 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G04 mock treatment 818440.0 203000.0 0.54 843720.0 149000.0 0.41 0.8894 0.8892 862030.0 313998.307291667 0.727312828187313 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G05 mock treatment 760420.0 145000.0 0.39 750740.0 55700.0 0.15 0.7128 0.8559 848350.0 300318.307291667 0.695625907402863 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G06 mock treatment 923310.0 308000.0 0.82 857840.0 163000.0 0.45 1.2576 0.9783 815720.0 267688.307291667 0.620045189186737 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G07 mock treatment 909780.0 295000.0 0.79 889140.0 194000.0 0.53 0.6378 0.5062 286120.0 -261911.692708333 -0.606664843521211 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G08 mock treatment 508750.0 -106000.0 -0.28 858560.0 163000.0 0.45 0.2806 0.3623 484360.0 -63671.692708333 -0.147482447592163 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G09 mock treatment 681540.0 66400.0 0.18 639780.0 -55300.0 -0.15 -0.3615 -0.5668 468400.0 -79631.692708333 -0.184450521840688 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G10 mock treatment 457020.0 -158000.0 -0.42 883900.0 189000.0 0.52 -0.2513 -0.263 582260.0 34228.307291667 0.0792828700100047 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G11 mock treatment 847620.0 232000.0 0.62 940510.0 245000.0 0.67 0.6609 0.7107 601990.0 53958.307291667 0.124983377837285 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G12 mock treatment 396060.0 -219000.0 -0.59 945250.0 250000.0 0.69 -0.1243 -0.0989 728880.0 180848.307291667 0.418898098476091 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G13 mock treatment 843730.0 229000.0 0.61 922490.0 227000.0 0.62 0.9532 0.8495 534040.0 -13991.692708333 -0.0324088931644236 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G14 mock treatment 567220.0 -47900.0 -0.13 774240.0 79200.0 0.22 -0.1796 -0.2806 602400.0 54368.307291667 0.125933058942667 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G15 mock treatment 565240.0 -49900.0 -0.13 742430.0 47400.0 0.13 0.6068 0.6889 820110.0 272078.307291667 0.630213725900461 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G16 mock treatment 285090.0 -330000.0 -0.88 692690.0 -2380.0 -0.01 -0.0511 -0.0478 791460.0 243428.307291667 0.563851863292676 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G17 mock treatment 553050.0 -62100.0 -0.17 768960.0 73900.0 0.2 -0.1351 -0.202 657510.0 109478.307291667 0.25358409727827 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G18 mock treatment 426430.0 -189000.0 -0.5 758890.0 63800.0 0.18 -0.2429 -0.344 651210.0 103178.307291667 0.238991436390694 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G19 mock treatment 500530.0 -115000.0 -0.31 493990.0 -201000.0 -0.55 -0.9002 -0.8534 185920.0 -362111.692708333 -0.838757640495033 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G20 mock treatment 671530.0 56400.0 0.15 673280.0 -21800.0 -0.06 -0.4651 -0.5784 231590.0 -316441.692708333 -0.732972430537005 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G21 mock treatment 270600.0 -345000.0 -0.92 776120.0 81000.0 0.22 -0.3181 -0.3219 475770.0 -72261.692708333 -0.167379424897604 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G22 mock treatment 673620.0 58500.0 0.16 771130.0 76100.0 0.21 -0.4751 -0.4914 277440.0 -270591.692708333 -0.626770287410759 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G23 mock treatment 669350.0 54200.0 0.14 573080.0 -122000.0 -0.33 -0.2206 -0.4167 389950.0 -158081.692708333 -0.36616389432169 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base G24 mock treatment 328000.0 -287000.0 -0.77 833090.0 138000.0 0.38 -0.109 -0.1168 476850.0 -71181.692708333 -0.164877825888305 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H01 mock treatment 336910.0 -278000.0 -0.74 663000.0 -32100.0 -0.09 -1.0782 -0.8943 299840.0 -248191.692708333 -0.574885270921602 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H02 mock treatment 297130.0 -318000.0 -0.85 933940.0 239000.0 0.66 0.6922 0.447 898940.0 350908.307291667 0.812807290625475 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H03 mock treatment 479410.0 -136000.0 -0.36 925720.0 231000.0 0.63 0.8201 0.662 921290.0 373258.307291667 0.864576492345684 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H04 mock treatment 599960.0 -15200.0 -0.04 931580.0 237000.0 0.65 0.1654 0.1636 259520.0 -288511.692708333 -0.668278300602086 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H05 mock treatment 240960.0 -374000.0 -1.0 707960.0 12900.0 0.04 -0.8696 -0.751 442080.0 -105951.692708333 -0.245415416215449 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H06 mock treatment 418120.0 -197000.0 -0.53 941200.0 246000.0 0.68 0.1153 0.0912 282460.0 -265571.692708333 -0.615142484608279 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H07 mock treatment 551970.0 -63200.0 -0.17 891310.0 196000.0 0.54 0.3054 0.3537 407450.0 -140581.692708333 -0.325628725189535 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H08 mock treatment 360800.0 -254000.0 -0.68 386740.0 -308000.0 -0.85 -0.7847 -0.5261 226400.0 -321631.692708333 -0.744994003553912 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H09 mock treatment 493860.0 -121000.0 -0.32 665760.0 -29300.0 -0.08 -0.0412 -0.0601 786720.0 238688.307291667 0.55287262319631 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H10 mock treatment 617760.0 2630.0 0.01 853020.0 158000.0 0.43 -0.0765 -0.1227 467680.0 -80351.692708333 -0.186118254513554 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H11 mock treatment 145700.0 -469000.0 -1.25 325850.0 -369000.0 -1.01 -1.6466 -0.9291 288640.0 -259391.692708333 -0.60082777916618 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H12 mock treatment 193380.0 -422000.0 -1.13 327680.0 -367000.0 -1.01 -1.0789 -0.5934 234960.0 -313071.692708333 -0.725166515109841 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H13 mock treatment 873870.0 259000.0 0.69 910330.0 215000.0 0.59 -0.1304 -0.0917 196800.0 -351231.692708333 -0.813556346771728 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H14 mock treatment 264980.0 -350000.0 -0.94 970790.0 276000.0 0.76 0.1465 0.1017 430800.0 -117231.692708333 -0.271543228090346 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H15 mock treatment 320710.0 -294000.0 -0.79 649990.0 -45100.0 -0.12 -0.5968 -0.6794 391460.0 -156571.692708333 -0.36266628829943 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H16 mock treatment 381870.0 -233000.0 -0.62 962150.0 267000.0 0.73 -0.0305 -0.0249 738600.0 190568.307291667 0.441412489559779 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H17 mock treatment 708100.0 93000.0 0.25 732050.0 37000.0 0.1 -0.2952 -0.3972 285300.0 -262731.692708333 -0.608564205731975 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H18 mock treatment 637120.0 22000.0 0.06 810940.0 116000.0 0.32 -0.1807 -0.1856 619260.0 71228.307291667 0.164985799032274 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H19 mock treatment 841340.0 226000.0 0.6 467550.0 -228000.0 -0.62 0.4035 0.383 760250.0 212218.307291667 0.491560284514702 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H20 mock treatment 865070.0 250000.0 0.67 767240.0 72200.0 0.2 -0.0798 -0.0749 433830.0 -114201.692708333 -0.264524853092036 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H21 mock treatment 493920.0 -121000.0 -0.32 583380.0 -112000.0 -0.31 -0.9948 -0.9386 262950.0 -285081.692708333 -0.660333407452184 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H22 mock treatment 348660.0 -266000.0 -0.71 721920.0 26800.0 0.07 -0.1832 -0.1739 377920.0 -170111.692708333 -0.394028927730822 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H23 mock treatment 697360.0 82200.0 0.22 780570.0 85500.0 0.23 -0.0796 -0.0866 642650.0 94618.307291667 0.219163947946623 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base H24 mock treatment 527290.0 -87800.0 -0.23 793550.0 98500.0 0.27 -0.1021 -0.1247 277440.0 -270591.692708333 -0.626770287410759 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I01 mock treatment 789890.0 175000.0 0.47 735650.0 40600.0 0.11 -0.0779 -0.1058 326430.0 -221601.692708333 -0.513294976794516 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I02 mock treatment 668640.0 53500.0 0.14 961600.0 267000.0 0.73 0.8778 0.8982 705760.0 157728.307291667 0.365345349314067 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I03 mock treatment 352320.0 -263000.0 -0.7 816800.0 122000.0 0.33 0.4584 0.3831 838770.0 290738.307291667 0.673435797672232 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I04 mock treatment 916580.0 301000.0 0.81 459160.0 -236000.0 -0.65 0.1317 0.1269 587840.0 39808.307291667 0.0922077982247146 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I05 mock treatment 461120.0 -154000.0 -0.41 397050.0 -298000.0 -0.82 -0.5843 -0.431 866010.0 317978.307291667 0.736531683795655 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I06 mock treatment 573680.0 -41400.0 -0.11 593480.0 -102000.0 -0.28 -0.9168 -0.8606 251000.0 -297031.692708333 -0.688013137230998 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I07 mock treatment 601550.0 -13600.0 -0.04 859910.0 165000.0 0.45 -0.0012 -0.0019 343630.0 -204401.692708333 -0.473454696276056 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I08 mock treatment 849450.0 234000.0 0.63 1005070.0 310000.0 0.85 0.8886 0.8245 606240.0 58208.307291667 0.134827633197951 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I09 mock treatment 892650.0 278000.0 0.74 664480.0 -30600.0 -0.08 -0.1137 -0.1139 424560.0 -123471.692708333 -0.285996911255183 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I10 mock treatment 896570.0 281000.0 0.75 886170.0 191000.0 0.52 0.5407 0.4529 276260.0 -271771.692708333 -0.629503515957956 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I11 mock treatment 543730.0 -71400.0 -0.19 819900.0 125000.0 0.34 0.0436 0.0427 246970.0 -301061.692708333 -0.697347807608288 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I12 mock treatment 667070.0 51900.0 0.14 602480.0 -92600.0 -0.25 0.0132 0.0148 322480.0 -225551.692708333 -0.522444343541488 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I13 mock treatment 581160.0 -34000.0 -0.09 757770.0 62700.0 0.17 0.28 0.4484 800110.0 252078.307291667 0.583887818320855 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I14 mock treatment 799360.0 184000.0 0.49 702510.0 7440.0 0.02 0.8555 0.8499 736810.0 188778.307291667 0.437266320831405 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I15 mock treatment 623310.0 8180.0 0.02 712750.0 17700.0 0.05 -0.3978 -0.6276 313930.0 -234101.692708333 -0.54224866903177 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I16 mock treatment 540330.0 -74800.0 -0.2 630430.0 -64600.0 -0.18 -0.2392 -0.2226 209210.0 -338821.692708333 -0.784811121118583 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I17 mock treatment 885120.0 270000.0 0.72 869050.0 174000.0 0.48 0.8864 0.9256 652550.0 104518.307291667 0.242095272198528 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I18 mock treatment 847400.0 232000.0 0.62 880010.0 185000.0 0.51 0.7091 0.6646 405000.0 -143031.692708333 -0.331303648868037 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I19 mock treatment 873440.0 258000.0 0.69 705650.0 10600.0 0.03 -0.27 -0.2388 305160.0 -242871.692708333 -0.562562579505427 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I20 mock treatment 747110.0 132000.0 0.35 574990.0 -120000.0 -0.33 -0.1856 -0.2716 342240.0 -205791.692708333 -0.476674346852838 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I21 mock treatment 449340.0 -166000.0 -0.44 514460.0 -181000.0 -0.5 -0.3945 -0.3896 349450.0 -198581.692708333 -0.459973857170391 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I22 mock treatment 349470.0 -266000.0 -0.71 464590.0 -230000.0 -0.63 -0.2701 -0.244 724880.0 176848.307291667 0.40963291696017 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I23 mock treatment 579420.0 -35700.0 -0.1 613130.0 -81900.0 -0.22 -0.8972 -0.8183 302090.0 -245941.692708333 -0.569673606318896 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base I24 mock treatment 609540.0 -5590.0 -0.01 625390.0 -69700.0 -0.19 0.0853 0.2039 708570.0 160538.307291667 0.371854139329002 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J01 mock treatment 400120.0 -215000.0 -0.57 890740.0 196000.0 0.54 0.6862 0.5376 892480.0 344448.307291667 0.797844022477262 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J02 mock treatment 754050.0 139000.0 0.37 825780.0 131000.0 0.36 0.3095 0.3648 728240.0 180208.307291667 0.417415669433544 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J03 mock treatment 525080.0 -90000.0 -0.24 703710.0 8640.0 0.02 -0.2933 -0.3299 219520.0 -328511.692708333 -0.760930115761296 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J04 mock treatment 865960.0 251000.0 0.67 321720.0 -373000.0 -1.03 0.1444 0.1066 795560.0 247528.307291667 0.573348674346495 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J05 mock treatment 841930.0 227000.0 0.61 527390.0 -168000.0 -0.46 0.4669 0.4928 745700.0 197668.307291667 0.457858186750539 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J06 mock treatment 484560.0 -131000.0 -0.35 632450.0 -62600.0 -0.17 -0.1981 -0.2184 326150.0 -221881.692708333 -0.513943539500631 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J07 mock treatment 799060.0 184000.0 0.49 902820.0 208000.0 0.57 0.8379 0.8205 844320.0 296288.307291667 0.686291237025573 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J08 mock treatment 617570.0 2440.0 0.01 536700.0 -158000.0 -0.43 0.2321 0.2447 911290.0 363258.307291667 0.841413538555881 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J09 mock treatment 701230.0 86100.0 0.23 375470.0 -320000.0 -0.88 -0.3818 -0.3295 304220.0 -243811.692708333 -0.564739897161668 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J10 mock treatment 861230.0 246000.0 0.66 817680.0 123000.0 0.34 1.0676 0.9751 780640.0 232608.307291667 0.53878954729211 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J11 mock treatment 583580.0 -31500.0 -0.08 577840.0 -117000.0 -0.32 -0.1334 -0.1714 790730.0 242698.307291667 0.56216096766602 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J12 mock treatment 647740.0 32600.0 0.09 975610.0 281000.0 0.77 0.3107 0.2524 784640.0 236608.307291667 0.548054728808031 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J13 mock treatment 806960.0 192000.0 0.51 684160.0 -10900.0 -0.03 0.2495 0.3275 723380.0 175348.307291667 0.4061584738917 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J14 mock treatment 629250.0 14100.0 0.04 475160.0 -220000.0 -0.6 -0.2347 -0.3575 643940.0 95908.307291667 0.222151968985507 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J15 mock treatment 671720.0 56600.0 0.15 645390.0 -49700.0 -0.14 -0.0021 -0.0031 344480.0 -203551.692708333 -0.471485845203923 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J16 mock treatment 809440.0 194000.0 0.52 698940.0 3870.0 0.01 0.2595 0.2836 775720.0 227688.307291667 0.527393374027527 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J17 mock treatment 808800.0 194000.0 0.52 897050.0 202000.0 0.55 0.5638 0.4145 904530.0 356498.307291667 0.825755381793974 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J18 mock treatment 850900.0 236000.0 0.63 848260.0 153000.0 0.42 0.7275 0.8851 592010.0 43978.307291667 0.101866749955062 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J19 mock treatment 805790.0 191000.0 0.51 586690.0 -108000.0 -0.3 -0.5829 -0.5084 291530.0 -256501.692708333 -0.594133685520928 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J20 mock treatment 387960.0 -227000.0 -0.61 609050.0 -86000.0 -0.24 -1.1533 -0.937 275270.0 -272761.692708333 -0.631796648383147 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J21 mock treatment 698240.0 83100.0 0.22 627950.0 -67100.0 -0.18 0.5215 0.6769 743230.0 195198.307291667 0.452136937164458 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J22 mock treatment 563590.0 -51500.0 -0.14 756980.0 61900.0 0.17 -0.3568 -0.5673 306580.0 -241451.692708333 -0.559273440067275 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J23 mock treatment 751110.0 136000.0 0.36 716870.0 21800.0 0.06 0.1269 0.1488 279600.0 -268431.692708333 -0.621767089392162 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base J24 mock treatment 344010.0 -271000.0 -0.72 409470.0 -286000.0 -0.78 -0.8072 -0.6893 670360.0 122328.307291667 0.283348492898166 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K01 mock treatment 903700.0 289000.0 0.77 751230.0 56200.0 0.15 1.0423 0.8605 926720.0 378688.307291667 0.877153976253547 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K02 mock treatment 911100.0 296000.0 0.79 653500.0 -41600.0 -0.11 1.0634 0.8156 830610.0 282578.307291667 0.654534827379753 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K03 mock treatment 777250.0 162000.0 0.43 417650.0 -277000.0 -0.76 0.5809 0.4201 925550.0 377518.307291667 0.87444391066014 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K04 mock treatment 866280.0 251000.0 0.67 398730.0 -296000.0 -0.81 -0.1456 -0.1006 214560.0 -333471.692708333 -0.772418940841038 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K05 mock treatment 745070.0 130000.0 0.35 524350.0 -171000.0 -0.47 0.7719 0.5859 935770.0 387738.307291667 0.898116449433318 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K06 mock treatment 260960.0 -354000.0 -0.95 731840.0 36800.0 0.1 -1.1356 -0.8183 221510.0 -326521.692708333 -0.756320687957126 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K07 mock treatment 218110.0 -397000.0 -1.06 1019480.0 324000.0 0.89 0.7647 0.4168 893360.0 345328.307291667 0.799882362410765 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K08 mock treatment 526190.0 -88900.0 -0.24 973890.0 279000.0 0.77 0.3369 0.2887 836400.0 288368.307291667 0.667946177624049 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K09 mock treatment 604590.0 -10500.0 -0.03 621670.0 -73400.0 -0.2 0.5856 0.5531 754590.0 206558.307291667 0.478450052669674 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K10 mock treatment 880440.0 265000.0 0.71 838130.0 143000.0 0.39 1.0889 0.9745 815040.0 267008.307291667 0.618470108329031 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K11 mock treatment 339750.0 -275000.0 -0.74 479260.0 -216000.0 -0.59 -0.5322 -0.4944 752010.0 203978.307291667 0.472474010591905 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K12 mock treatment 208210.0 -407000.0 -1.09 221480.0 -474000.0 -1.3 -1.1969 -0.6165 835840.0 287808.307291667 0.66664905221182 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K13 mock treatment 937980.0 323000.0 0.86 232090.0 -463000.0 -1.27 -0.1514 -0.0864 827230.0 279198.307291667 0.6467057489988 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K14 mock treatment 684320.0 69200.0 0.18 912880.0 218000.0 0.6 0.6747 0.7391 508500.0 -39531.692708333 -0.0915670771435796 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K15 mock treatment 594400.0 -20700.0 -0.06 351460.0 -344000.0 -0.94 -0.3628 -0.2653 311040.0 -236991.692708333 -0.548942762677023 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K16 mock treatment 791400.0 176000.0 0.47 1065360.0 370000.0 1.02 0.5912 0.477 629920.0 81888.307291667 0.189677507772204 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K17 mock treatment 931520.0 316000.0 0.85 992720.0 298000.0 0.82 1.424 0.9843 776750.0 228718.307291667 0.529779158267876 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K18 mock treatment 912030.0 297000.0 0.79 360380.0 -335000.0 -0.92 0.8345 0.4735 890480.0 342448.307291667 0.793211431719302 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K19 mock treatment 417680.0 -197000.0 -0.53 826010.0 131000.0 0.36 -0.0406 -0.0423 785090.0 237058.307291667 0.549097061728572 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K20 mock treatment 517290.0 -97800.0 -0.26 419310.0 -276000.0 -0.76 -0.8447 -0.9004 438650.0 -109381.692708333 -0.253360309365351 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K21 mock treatment 907840.0 293000.0 0.78 619630.0 -75400.0 -0.21 0.1977 0.2235 611770.0 63738.307291667 0.147636746643712 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K22 mock treatment 441990.0 -173000.0 -0.46 528970.0 -166000.0 -0.46 -0.3005 -0.3178 814820.0 266788.307291667 0.617960523345655 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K23 mock treatment 571050.0 -44100.0 -0.12 807720.0 113000.0 0.31 0.35 0.4647 482840.0 -65191.692708333 -0.151003216568213 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base K24 mock treatment 386020.0 -229000.0 -0.61 535560.0 -160000.0 -0.44 -0.6742 -0.8564 512550.0 -35481.692708333 -0.0821860808587095 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L01 mock treatment 776640.0 162000.0 0.43 952900.0 258000.0 0.71 1.1748 0.9587 896730.0 348698.307291667 0.807688277837928 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L02 mock treatment 340360.0 -275000.0 -0.73 729970.0 34900.0 0.1 -0.2945 -0.3215 394250.0 -153781.692708333 -0.356203824192075 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L03 mock treatment 857760.0 243000.0 0.65 918510.0 223000.0 0.61 1.194 0.9979 782500.0 234468.307291667 0.543097856697013 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L04 mock treatment 798940.0 184000.0 0.49 897860.0 203000.0 0.56 -0.2647 -0.1964 253410.0 -294621.692708333 -0.682430865367655 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L05 mock treatment 464820.0 -150000.0 -0.4 506800.0 -188000.0 -0.52 -0.6098 -0.5811 241210.0 -306821.692708333 -0.710689668991214 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L06 mock treatment 713360.0 98200.0 0.26 714960.0 19900.0 0.05 0.5072 0.7445 816450.0 268418.307291667 0.621736084813393 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L07 mock treatment 530080.0 -85000.0 -0.23 624960.0 -70100.0 -0.19 -0.5551 -0.8391 297440.0 -250591.692708333 -0.580444379831154 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L08 mock treatment 768230.0 153000.0 0.41 666240.0 -28800.0 -0.08 0.335 0.4501 794850.0 246818.307291667 0.571704104627419 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L09 mock treatment 822120.0 207000.0 0.55 884330.0 189000.0 0.52 0.7176 0.7024 432740.0 -115291.692708333 -0.267049615055124 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L10 mock treatment 597290.0 -17800.0 -0.05 910640.0 216000.0 0.59 0.0257 0.0338 539710.0 -8321.69270833302 -0.0192754983656055 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L11 mock treatment 368490.0 -247000.0 -0.66 465630.0 -229000.0 -0.63 0.1062 0.0754 824230.0 276198.307291667 0.639756862861859 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L12 mock treatment 385060.0 -230000.0 -0.61 346900.0 -348000.0 -0.96 -0.575 -0.4707 741250.0 193218.307291667 0.447550672314077 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L13 mock treatment 926470.0 311000.0 0.83 620930.0 -74100.0 -0.2 0.0098 0.0101 459610.0 -88421.692708333 -0.204810758221925 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L14 mock treatment 383040.0 -232000.0 -0.62 563270.0 -132000.0 -0.36 -0.5874 -0.6667 356120.0 -191911.692708333 -0.444524166992592 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L15 mock treatment 788990.0 174000.0 0.46 890350.0 195000.0 0.54 0.3809 0.384 291200.0 -256831.692708333 -0.594898062995991 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L16 mock treatment 403380.0 -212000.0 -0.57 931040.0 236000.0 0.65 0.0267 0.0247 741120.0 193088.307291667 0.44724955391481 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L17 mock treatment 821480.0 206000.0 0.55 626670.0 -68400.0 -0.19 -0.4276 -0.4076 327150.0 -220881.692708333 -0.511627244121651 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L18 mock treatment 791140.0 176000.0 0.47 661640.0 -33400.0 -0.09 0.5741 0.6617 568750.0 20718.307291667 0.0479897194399813 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L19 mock treatment 866720.0 252000.0 0.67 780970.0 85900.0 0.24 0.5752 0.744 675850.0 127818.307291667 0.296064954528768 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L20 mock treatment 668320.0 53200.0 0.14 737960.0 42900.0 0.12 0.1764 0.2213 332260.0 -215771.692708333 -0.499790974735061 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L21 mock treatment 865130.0 250000.0 0.67 884420.0 189000.0 0.52 0.7437 0.7624 745990.0 197958.307291667 0.458529912410443 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L22 mock treatment 518360.0 -96800.0 -0.26 650400.0 -44700.0 -0.12 -0.3961 -0.8358 385600.0 -162431.692708333 -0.376239779220254 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L23 mock treatment 742730.0 128000.0 0.34 474720.0 -220000.0 -0.6 0.3455 0.346 828500.0 280468.307291667 0.649647444130105 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base L24 mock treatment 548680.0 -66400.0 -0.18 617490.0 -77600.0 -0.21 0.0144 0.024 502620.0 -45411.692708333 -0.105186893971984 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M01 mock treatment 512750.0 -102000.0 -0.27 879720.0 185000.0 0.51 0.7302 0.6736 720990.0 172958.307291667 0.400622527935937 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M02 mock treatment 826640.0 212000.0 0.56 601980.0 -93100.0 -0.26 0.6684 0.6998 767040.0 219008.307291667 0.507287930137978 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M03 mock treatment 752410.0 137000.0 0.37 804580.0 110000.0 0.3 0.4832 0.552 397440.0 -150591.692708333 -0.348814841933128 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M04 mock treatment 805280.0 190000.0 0.51 888680.0 194000.0 0.53 0.976 0.9643 824280.0 276248.307291667 0.639872677630808 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M05 mock treatment 790440.0 175000.0 0.47 881880.0 187000.0 0.51 0.3143 0.3346 649500.0 101468.307291667 0.235030571292638 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M06 mock treatment 268120.0 -347000.0 -0.93 746110.0 51000.0 0.14 -0.8154 -0.7215 302930.0 -245101.692708333 -0.567727918200553 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M07 mock treatment 721410.0 106000.0 0.28 798930.0 104000.0 0.29 0.5209 0.8658 559370.0 11338.307291667 0.0262628687851465 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M08 mock treatment 887470.0 272000.0 0.73 902240.0 207000.0 0.57 1.0705 0.9284 836090.0 288058.307291667 0.667228126056565 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M09 mock treatment 670580.0 55500.0 0.15 585250.0 -110000.0 -0.3 0.0422 0.0523 817380.0 269348.307291667 0.623890239515844 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M10 mock treatment 643840.0 28700.0 0.08 749040.0 54000.0 0.15 0.3312 0.486 820680.0 272648.307291667 0.631534014266479 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M11 mock treatment 801440.0 186000.0 0.5 662560.0 -32500.0 -0.09 0.8232 0.814 806730.0 258698.307291667 0.599221693729705 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M12 mock treatment 916820.0 302000.0 0.81 934050.0 239000.0 0.66 0.8615 0.5991 902610.0 354578.307291667 0.821308094666332 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M13 mock treatment 463740.0 -151000.0 -0.4 794350.0 99300.0 0.27 -0.0136 -0.0256 511040.0 -36991.692708333 -0.0856836868809697 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M14 mock treatment 860910.0 246000.0 0.66 348830.0 -346000.0 -0.95 -0.3744 -0.3092 398930.0 -149101.692708333 -0.345363561818447 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M15 mock treatment 434980.0 -180000.0 -0.48 736960.0 41900.0 0.12 0.1533 0.2085 612660.0 64628.307291667 0.149698249531005 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M16 mock treatment 742400.0 127000.0 0.34 803640.0 109000.0 0.3 0.523 0.6513 453670.0 -94361.692708333 -0.218569552773068 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M17 mock treatment 773970.0 159000.0 0.42 833990.0 139000.0 0.38 0.7827 0.8259 549330.0 1298.30729166698 0.0030072631801846 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M18 mock treatment 802150.0 187000.0 0.5 685540.0 -9530.0 -0.03 0.0886 0.1003 271280.0 -276751.692708333 -0.641038666945278 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M19 mock treatment 906440.0 291000.0 0.78 817860.0 123000.0 0.34 0.4843 0.4431 724410.0 176378.307291667 0.408544258132049 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M20 mock treatment 560320.0 -54800.0 -0.15 885480.0 190000.0 0.52 0.063 0.0675 268560.0 -279471.692708333 -0.647338990376104 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M21 mock treatment 965540.0 350000.0 0.94 896160.0 201000.0 0.55 0.3018 0.2391 312610.0 -235421.692708333 -0.545306178932024 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M22 mock treatment 918480.0 303000.0 0.81 617240.0 -77800.0 -0.21 0.5829 0.5416 836500.0 288468.307291667 0.668177807161947 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M23 mock treatment 813990.0 199000.0 0.53 764230.0 69200.0 0.19 0.4086 0.3898 837730.0 289698.307291667 0.671026850478093 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base M24 mock treatment 419090.0 -196000.0 -0.52 632060.0 -63000.0 -0.17 0.2689 0.2604 815880.0 267848.307291667 0.620415796447374 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N01 mock treatment 505480.0 -110000.0 -0.29 887040.0 192000.0 0.53 0.5595 0.6436 747230.0 199198.307291667 0.461402118680379 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N02 mock treatment 851130.0 236000.0 0.63 413960.0 -281000.0 -0.77 0.2576 0.1976 903520.0 355488.307291667 0.823415923461204 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N03 mock treatment 690880.0 75800.0 0.2 841050.0 146000.0 0.4 0.9706 0.9267 832000.0 283968.307291667 0.657754477956536 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N04 mock treatment 665140.0 50000.0 0.13 646450.0 -48600.0 -0.13 -0.0256 -0.0424 711800.0 163768.307291667 0.379335773403108 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N05 mock treatment 645660.0 30500.0 0.08 499840.0 -195000.0 -0.54 0.3492 0.3548 827750.0 279718.307291667 0.64791022259587 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N06 mock treatment 639880.0 24800.0 0.07 323240.0 -372000.0 -1.02 -0.2267 -0.1855 829120.0 281088.307291667 0.651083547265073 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N07 mock treatment 834120.0 219000.0 0.58 830830.0 136000.0 0.37 1.0297 0.9816 819800.0 271768.307291667 0.629495674332977 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N08 mock treatment 732030.0 117000.0 0.31 894690.0 200000.0 0.55 0.4234 0.5327 692720.0 144688.307291667 0.335140857572165 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N09 mock treatment 866650.0 252000.0 0.67 733210.0 38100.0 0.1 0.4909 0.5383 412200.0 -135831.692708333 -0.314626322139379 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N10 mock treatment 812750.0 198000.0 0.53 941880.0 247000.0 0.68 1.0388 0.9168 612000.0 63968.307291667 0.148169494580878 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N11 mock treatment 870370.0 255000.0 0.68 966000.0 271000.0 0.74 1.1021 0.8767 560730.0 12698.307291667 0.0294130305005596 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N12 mock treatment 885710.0 271000.0 0.72 609560.0 -85500.0 -0.23 0.1246 0.126 682490.0 134458.307291667 0.311445155845197 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N13 mock treatment 806770.0 192000.0 0.51 612640.0 -82400.0 -0.23 -0.3592 -0.3953 303090.0 -244941.692708333 -0.567357310939916 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N14 mock treatment 868320.0 253000.0 0.68 867420.0 172000.0 0.47 0.8864 0.9472 678760.0 130728.307291667 0.3028053740816 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N15 mock treatment 861670.0 247000.0 0.66 872990.0 178000.0 0.49 0.1172 0.1055 467310.0 -80721.692708333 -0.186975283803777 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N16 mock treatment 899650.0 285000.0 0.76 872280.0 177000.0 0.49 1.1661 0.944 675680.0 127648.307291667 0.295671184314341 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N17 mock treatment 848290.0 233000.0 0.62 773800.0 78700.0 0.22 0.5236 0.5377 378840.0 -169191.692708333 -0.391897935982161 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N18 mock treatment 582030.0 -33100.0 -0.09 648570.0 -46500.0 -0.13 0.3929 0.54 782000.0 233968.307291667 0.541939709007523 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N19 mock treatment 641010.0 25900.0 0.07 688840.0 -6230.0 -0.02 -0.2189 -0.4079 319050.0 -228981.692708333 -0.530389236691391 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N20 mock treatment 844710.0 230000.0 0.61 566850.0 -128000.0 -0.35 0.2167 0.272 479530.0 -68501.692708333 -0.158670154272638 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N21 mock treatment 801400.0 186000.0 0.5 706720.0 11600.0 0.03 0.315 0.4811 441960.0 -106071.692708333 -0.245693371660926 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N22 mock treatment 380220.0 -235000.0 -0.63 712160.0 17100.0 0.05 -0.2257 -0.2402 787130.0 239098.307291667 0.553822304301691 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N23 mock treatment 715890.0 101000.0 0.27 832990.0 138000.0 0.38 0.9378 0.933 874760.0 326728.307291667 0.756799268361732 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base N24 mock treatment 722750.0 108000.0 0.29 643040.0 -52000.0 -0.14 0.3511 0.6892 678080.0 130048.307291667 0.301230293223894 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O01 mock treatment 749710.0 135000.0 0.36 840110.0 145000.0 0.4 0.4224 0.6272 444000.0 -104031.692708333 -0.240968129087807 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O02 mock treatment 432960.0 -182000.0 -0.49 810650.0 116000.0 0.32 0.0447 0.0623 487950.0 -60081.692708333 -0.139166947181624 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O03 mock treatment 474730.0 -140000.0 -0.37 825470.0 130000.0 0.36 -0.2384 -0.2658 648960.0 100928.307291667 0.233779771787988 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O04 mock treatment 498080.0 -117000.0 -0.31 711770.0 16700.0 0.05 -0.671 -0.7886 381470.0 -166561.692708333 -0.385806079135443 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O05 mock treatment 799780.0 185000.0 0.49 769570.0 74500.0 0.2 0.4579 0.597 756440.0 208408.307291667 0.482735199120787 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O06 mock treatment 779390.0 164000.0 0.44 604540.0 -90500.0 -0.25 -0.4784 -0.5003 315650.0 -232381.692708333 -0.538264640979924 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O07 mock treatment 558750.0 -56400.0 -0.15 765180.0 70100.0 0.19 -0.059 -0.0995 352390.0 -195641.692708333 -0.453163948756189 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O08 mock treatment 565250.0 -49900.0 -0.13 810480.0 115000.0 0.32 0.0996 0.1111 298510.0 -249521.692708333 -0.577965943775645 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O09 mock treatment 713660.0 98500.0 0.26 627160.0 -67900.0 -0.19 -0.4323 -0.5484 261540.0 -286491.692708333 -0.663599383936546 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O10 mock treatment 770670.0 156000.0 0.42 534460.0 -161000.0 -0.44 -0.0951 -0.121 363840.0 -184191.692708333 -0.426642366666865 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O11 mock treatment 789250.0 174000.0 0.47 312710.0 -382000.0 -1.05 -0.6114 -0.4801 506880.0 -41151.692708333 -0.0953194756575276 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O12 mock treatment 414170.0 -201000.0 -0.54 287130.0 -408000.0 -1.12 -1.2779 -0.8904 456650.0 -91381.692708333 -0.211666992543706 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O13 mock treatment 834080.0 219000.0 0.58 690460.0 -4610.0 -0.01 0.2377 0.2261 793120.0 245088.307291667 0.567696913621783 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O14 mock treatment 807760.0 193000.0 0.51 801940.0 107000.0 0.29 0.0604 0.0785 377200.0 -170831.692708333 -0.395696660403688 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O15 mock treatment 506080.0 -109000.0 -0.29 929150.0 234000.0 0.64 -0.3106 -0.3144 359840.0 -188191.692708333 -0.435907548182786 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O16 mock treatment 261790.0 -353000.0 -0.94 605880.0 -89200.0 -0.24 -0.931 -0.8328 484840.0 -63191.692708333 -0.146370625810253 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O17 mock treatment 850520.0 235000.0 0.63 763550.0 68500.0 0.19 0.0476 0.0565 349860.0 -198171.692708333 -0.459024176065009 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O18 mock treatment 748280.0 133000.0 0.36 521760.0 -173000.0 -0.48 -0.1696 -0.2006 678140.0 130108.307291667 0.301369270946632 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O19 mock treatment 620660.0 5530.0 0.01 804240.0 109000.0 0.3 -0.0261 -0.0519 563000.0 14968.307291667 0.0346710210108448 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O20 mock treatment 814330.0 199000.0 0.53 828220.0 133000.0 0.37 0.2369 0.2995 561960.0 13928.307291667 0.0322620738167053 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O21 mock treatment 709960.0 94800.0 0.25 888350.0 193000.0 0.53 -0.1531 -0.1568 276220.0 -271811.692708333 -0.629596167773115 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O22 mock treatment 818620.0 203000.0 0.54 717830.0 22800.0 0.06 0.2483 0.2429 261880.0 -286151.692708333 -0.662811843507692 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O23 mock treatment 693870.0 78700.0 0.21 691120.0 -3950.0 -0.01 -0.3721 -0.4506 478210.0 -69821.692708333 -0.161727664172892 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base O24 mock treatment 516680.0 -98400.0 -0.26 575280.0 -120000.0 -0.33 -0.6906 -0.9834 397600.0 -150431.692708333 -0.348444234672491 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P01 mock treatment 262300.0 -353000.0 -0.94 498280.0 -197000.0 -0.54 -1.2585 -0.9564 285320.0 -262711.692708333 -0.608517879824395 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P02 mock treatment 292880.0 -322000.0 -0.86 524930.0 -170000.0 -0.47 -0.6446 -0.6507 511840.0 -36191.692708333 -0.0838306505777855 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P03 mock treatment 449990.0 -165000.0 -0.44 271770.0 -423000.0 -1.16 -0.9009 -0.7019 417440.0 -130591.692708333 -0.302488934353522 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P04 mock treatment 282630.0 -332000.0 -0.89 342670.0 -352000.0 -0.97 -1.192 -0.8376 556450.0 8418.30729166698 0.0194992862785241 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P05 mock treatment 225880.0 -389000.0 -1.04 418360.0 -277000.0 -0.76 -0.7804 -0.5993 570360.0 22328.307291667 0.0517189550001396 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P06 mock treatment 280160.0 -335000.0 -0.89 664760.0 -30300.0 -0.08 -0.6527 -0.6756 395200.0 -152831.692708333 -0.354003343582044 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P07 mock treatment 359490.0 -256000.0 -0.68 289130.0 -406000.0 -1.11 -1.5514 -0.9683 290720.0 -257311.692708333 -0.596009884777902 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P08 mock treatment 246080.0 -369000.0 -0.99 689180.0 -5890.0 -0.02 -0.7521 -0.6431 281160.0 -266871.692708333 -0.618153668600953 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P09 mock treatment 269400.0 -346000.0 -0.92 350030.0 -345000.0 -0.95 -1.557 -0.9731 220980.0 -327051.692708333 -0.757548324507985 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P10 mock treatment 236160.0 -379000.0 -1.01 292050.0 -403000.0 -1.11 -1.6034 -0.9512 319120.0 -228911.692708333 -0.530227096014862 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P11 mock treatment 313480.0 -302000.0 -0.81 279270.0 -416000.0 -1.14 -1.7865 -0.9869 180800.0 -367231.692708333 -0.850617072835412 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P12 mock treatment 320610.0 -295000.0 -0.79 338790.0 -356000.0 -0.98 -1.5413 -0.9849 242180.0 -305851.692708333 -0.708442862473604 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P13 mock treatment 330890.0 -284000.0 -0.76 373280.0 -322000.0 -0.88 -1.0842 -0.7722 223840.0 -324191.692708333 -0.750923719724102 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P14 mock treatment 444000.0 -171000.0 -0.46 355840.0 -339000.0 -0.93 -0.9813 -0.8488 329760.0 -218271.692708333 -0.505581713182512 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P15 mock treatment 258680.0 -356000.0 -0.95 272700.0 -422000.0 -1.16 -1.8419 -0.9859 226260.0 -321771.692708333 -0.745318284906969 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P16 mock treatment 225760.0 -389000.0 -1.04 420680.0 -274000.0 -0.75 -1.5691 -0.9818 267100.0 -280931.692708333 -0.650720781629415 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P17 mock treatment 217830.0 -397000.0 -1.06 387570.0 -308000.0 -0.84 -1.4412 -0.9407 390970.0 -157061.692708333 -0.36380127303513 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P18 mock treatment 334740.0 -280000.0 -0.75 320390.0 -375000.0 -1.03 -1.5862 -0.9846 228860.0 -319171.692708333 -0.739295916921621 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P19 mock treatment 270580.0 -345000.0 -0.92 287580.0 -407000.0 -1.12 -1.5267 -0.9429 357550.0 -190481.692708333 -0.44121186460065 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P20 mock treatment 411070.0 -204000.0 -0.55 396070.0 -299000.0 -0.82 -1.3158 -0.988 261920.0 -286111.692708333 -0.662719191692533 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P21 mock treatment 246250.0 -369000.0 -0.99 270760.0 -424000.0 -1.16 -1.7615 -0.9739 239160.0 -308871.692708333 -0.715438074518124 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P22 mock treatment 262660.0 -352000.0 -0.94 256800.0 -438000.0 -1.2 -1.7731 -0.9706 289790.0 -258241.692708333 -0.598164039480353 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P23 mock treatment 411800.0 -203000.0 -0.54 425010.0 -270000.0 -0.74 -1.0693 -0.8932 219200.0 -328831.692708333 -0.76167133028257 1001.0080 CellTiterGlo(1001.0080) MODYPatientCellProfiling 1001.0080.Base P24 mock treatment 228420.0 -387000.0 -1.03 379150.0 -316000.0 -0.87 -1.3262 -0.903 314190.0 -233841.692708333 -0.541646432233235