ASSAY_ID ASSAY PROJECT PLATE WELL WELL_TYPE RAW_VALUE_A BSUB_VALUE_A Z_SCORE_A RAW_VALUE_B BSUB_VALUE_B Z_SCORE_B COMPOSITE_Z REPRODUCIBILITY CHEMBANK_ID VIRTUAL_ID SMILES RAW_VALUE_C BSUB_VALUE_C Z_SCORE_C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A01 compound treatment 106990.0 -370000.0 -3.15 132030.0 -388000.0 -3.29 -4.5529 -0.9997 3186889 PK04_093001 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A02 compound treatment 167650.0 -309000.0 -2.63 178850.0 -341000.0 -2.9 -3.9071 -0.9988 3067555 PK04_093002 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A03 compound treatment 395070.0 -81600.0 -0.69 352530.0 -168000.0 -1.42 -1.4973 -0.9455 3186890 PK04_093003 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A04 compound treatment 242980.0 -234000.0 -1.99 373480.0 -147000.0 -1.25 -2.2866 -0.9746 3186891 PK04_093004 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A05 compound treatment 247040.0 -230000.0 -1.95 386720.0 -134000.0 -1.13 -2.1827 -0.9665 3067558 PK04_093005 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A06 compound treatment 257870.0 -219000.0 -1.86 250450.0 -270000.0 -2.29 -2.935 -0.9947 3186892 PK04_093006 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A07 compound treatment 222310.0 -254000.0 -2.16 239570.0 -281000.0 -2.38 -3.2141 -0.9989 3067559 PK04_093007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A08 compound treatment 410170.0 -66500.0 -0.57 423210.0 -97100.0 -0.82 -0.9825 -0.9832 3186893 PK04_093008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A09 compound treatment 388680.0 -88000.0 -0.75 414420.0 -106000.0 -0.9 -1.1645 -0.9959 3186894 PK04_093009 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A10 compound treatment 208930.0 -268000.0 -2.28 257510.0 -263000.0 -2.23 -3.187 -0.9999 3067560 PK04_093010 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A11 compound treatment 338280.0 -138000.0 -1.18 409450.0 -111000.0 -0.94 -1.4975 -0.9938 3186895 PK04_093011 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A12 compound treatment 348000.0 -129000.0 -1.09 400230.0 -120000.0 -1.02 -1.4944 -0.9994 3186896 PK04_093012 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A13 mock treatment 294290.0 -182000.0 -1.55 404800.0 -116000.0 -0.98 -1.79 -0.9754 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A14 mock treatment 367420.0 -109000.0 -0.93 431150.0 -89200.0 -0.76 -1.1921 -0.9948 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A15 compound treatment 191940.0 -285000.0 -2.42 225730.0 -295000.0 -2.5 -3.4798 -0.9999 3067562 PK04_093013 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A16 compound treatment 207160.0 -270000.0 -2.29 249190.0 -271000.0 -2.3 -3.2476 -1.0 3186897 PK04_093014 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A17 compound treatment 403610.0 -73100.0 -0.62 351360.0 -169000.0 -1.43 -1.453 -0.9301 3067564 PK04_093015 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A18 compound treatment 314950.0 -162000.0 -1.38 305200.0 -215000.0 -1.82 -2.2632 -0.9903 3186898 PK04_093016 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A19 compound treatment 167520.0 -309000.0 -2.63 228970.0 -291000.0 -2.47 -3.6073 -0.9995 3186899 PK04_093017 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A20 compound treatment 335480.0 -141000.0 -1.2 364990.0 -155000.0 -1.32 -1.7811 -0.9989 3067604 PK04_093018 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A21 compound treatment 433630.0 -43000.0 -0.37 278970.0 -241000.0 -2.05 -1.7066 -0.8206 3186900 PK04_093019 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A22 compound treatment 411280.0 -65400.0 -0.56 304770.0 -216000.0 -1.83 -1.6863 -0.8823 3067607 PK04_093020 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A23 compound treatment 439230.0 -37400.0 -0.32 391070.0 -129000.0 -1.1 -1.0005 -0.8763 3186901 PK04_093021 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 A24 compound treatment 212690.0 -264000.0 -2.25 391600.0 -129000.0 -1.09 -2.3601 -0.9451 3186902 PK04_093022 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B01 compound treatment 315570.0 -161000.0 -1.37 366520.0 -154000.0 -1.3 -1.8916 -0.9997 3067612 PK04_093023 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B02 compound treatment 469700.0 -6980.0 -0.06 507280.0 -13000.0 -0.11 -0.1202 -0.9575 3186903 PK04_093024 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B03 compound treatment 414320.0 -62400.0 -0.53 358910.0 -161000.0 -1.37 -1.3433 -0.9148 3067614 PK04_093025 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B04 compound treatment 427240.0 -49400.0 -0.42 441650.0 -78700.0 -0.67 -0.7692 -0.9752 3186904 PK04_093026 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B05 compound treatment 346270.0 -130000.0 -1.11 216540.0 -304000.0 -2.58 -2.6066 -0.9291 3186905 PK04_093027 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B06 compound treatment 414530.0 -62100.0 -0.53 416800.0 -104000.0 -0.88 -0.9948 -0.9705 3068180 PK04_093028 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B07 compound treatment 375260.0 -101000.0 -0.86 271480.0 -249000.0 -2.11 -2.1026 -0.9221 3186906 PK04_093029 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B08 compound treatment 179840.0 -297000.0 -2.53 246500.0 -274000.0 -2.32 -3.428 -0.9991 3186992 PK04_093030 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B09 compound treatment 358050.0 -119000.0 -1.01 464360.0 -56000.0 -0.47 -1.0492 -0.9408 3068181 PK04_093031 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B10 compound treatment 238920.0 -238000.0 -2.02 285210.0 -235000.0 -1.99 -2.8405 -1.0 3186993 PK04_093032 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B11 compound treatment 349290.0 -127000.0 -1.08 292740.0 -228000.0 -1.93 -2.1313 -0.9627 3068182 PK04_093033 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B12 compound treatment 342830.0 -134000.0 -1.14 414020.0 -106000.0 -0.9 -1.4427 -0.9933 3186994 PK04_093034 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B13 mock treatment 484450.0 7770.0 0.07 541560.0 21200.0 0.18 0.1742 0.9074 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B14 mock treatment 453000.0 -23700.0 -0.2 549640.0 29300.0 0.25 0.0335 0.1045 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B15 compound treatment 469600.0 -7080.0 -0.06 480930.0 -39400.0 -0.33 -0.2788 -0.8213 3068183 PK04_093035 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B16 compound treatment 324220.0 -152000.0 -1.3 336430.0 -184000.0 -1.56 -2.0201 -0.9958 3186995 PK04_093036 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B17 compound treatment 232900.0 -244000.0 -2.07 256820.0 -263000.0 -2.24 -3.047 -0.9993 3186996 PK04_093037 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B18 compound treatment 416390.0 -60300.0 -0.51 420450.0 -99900.0 -0.85 -0.9617 -0.9711 3068184 PK04_093038 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B19 compound treatment 375630.0 -101000.0 -0.86 382880.0 -137000.0 -1.17 -1.4322 -0.9888 3186997 PK04_093039 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B20 compound treatment 309540.0 -167000.0 -1.42 282970.0 -237000.0 -2.01 -2.4291 -0.9855 3186998 PK04_093040 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B21 compound treatment 324000.0 -153000.0 -1.3 432420.0 -87900.0 -0.75 -1.4457 -0.9653 3068185 PK04_093041 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B22 compound treatment 396530.0 -80100.0 -0.68 466780.0 -53500.0 -0.45 -0.8032 -0.9805 3186999 PK04_093042 CN(C)C(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B23 compound treatment 411450.0 -65200.0 -0.55 319420.0 -201000.0 -1.7 -1.5974 -0.8913 3068186 PK04_093043 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 B24 compound treatment 341470.0 -135000.0 -1.15 287640.0 -233000.0 -1.97 -2.209 -0.967 3187000 PK04_093044 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C01 compound treatment 70400.0 -406000.0 -3.46 79800.0 -441000.0 -3.74 -5.0863 -0.9992 3187001 PK04_093045 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C02 compound treatment 204720.0 -272000.0 -2.31 254240.0 -266000.0 -2.26 -3.2319 -0.9999 3068187 PK04_093046 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C03 compound treatment 318560.0 -158000.0 -1.35 334530.0 -186000.0 -1.58 -2.0655 -0.9969 3187002 PK04_093047 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C04 compound treatment 342510.0 -134000.0 -1.14 356900.0 -163000.0 -1.39 -1.7873 -0.9953 3068188 PK04_093048 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C05 compound treatment 354840.0 -122000.0 -1.04 333920.0 -186000.0 -1.58 -1.851 -0.979 3187003 PK04_093049 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C06 compound treatment 280480.0 -196000.0 -1.67 338680.0 -182000.0 -1.54 -2.2697 -0.9992 3187004 PK04_093050 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C07 compound treatment 379430.0 -97200.0 -0.83 455300.0 -65000.0 -0.55 -0.975 -0.9806 3068189 PK04_093051 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C08 compound treatment 380260.0 -96400.0 -0.82 371970.0 -148000.0 -1.26 -1.4698 -0.9785 3187005 PK04_093052 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C09 compound treatment 424900.0 -51800.0 -0.44 406490.0 -114000.0 -0.97 -0.9942 -0.9368 3187006 PK04_093053 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C10 compound treatment 194560.0 -282000.0 -2.4 276610.0 -244000.0 -2.07 -3.1589 -0.9972 3068190 PK04_093054 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C11 mock treatment 431680.0 -45000.0 -0.38 451070.0 -69200.0 -0.59 -0.686 -0.9785 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C12 mock treatment 410410.0 -66300.0 -0.56 433950.0 -86400.0 -0.73 -0.9167 -0.9916 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C13 compound treatment 213180.0 -263000.0 -2.24 263700.0 -257000.0 -2.18 -3.1243 -0.9999 3187007 PK04_093055 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C14 compound treatment 241240.0 -235000.0 -2.0 332730.0 -188000.0 -1.59 -2.5415 -0.9935 3068191 PK04_093056 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C15 mock treatment 410900.0 -65800.0 -0.56 459480.0 -60800.0 -0.52 -0.7606 -0.9992 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C16 mock treatment 434590.0 -42100.0 -0.36 471330.0 -49000.0 -0.42 -0.547 -0.9973 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C17 compound treatment 205860.0 -271000.0 -2.3 313920.0 -206000.0 -1.75 -2.8671 -0.9908 3187008 PK04_093057 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C18 compound treatment 234530.0 -242000.0 -2.06 365770.0 -155000.0 -1.31 -2.3836 -0.9762 3068193 PK04_093058 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C19 compound treatment 212080.0 -265000.0 -2.25 283540.0 -237000.0 -2.01 -3.0119 -0.9984 3187009 PK04_093059 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C20 compound treatment 311630.0 -165000.0 -1.4 276210.0 -244000.0 -2.07 -2.457 -0.9821 3187010 PK04_093060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C21 compound treatment 355080.0 -122000.0 -1.03 388580.0 -132000.0 -1.12 -1.5217 -0.9993 3068197 PK04_093061 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C22 compound treatment 381890.0 -94800.0 -0.81 394930.0 -125000.0 -1.06 -1.3223 -0.9907 3187011 PK04_093062 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C23 compound treatment 407240.0 -69400.0 -0.59 451300.0 -69000.0 -0.59 -0.8317 -1.0 3068199 PK04_093063 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 C24 compound treatment 391850.0 -84800.0 -0.72 386840.0 -133000.0 -1.13 -1.3109 -0.9763 3187012 PK04_093064 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCCCC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D01 compound treatment 385460.0 -91200.0 -0.78 471310.0 -49000.0 -0.42 -0.8427 -0.9572 3187091 PK04_093065 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D02 compound treatment 379120.0 -97600.0 -0.83 394320.0 -126000.0 -1.07 -1.3426 -0.9922 3068202 PK04_093066 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D03 compound treatment 425200.0 -51500.0 -0.44 485380.0 -34900.0 -0.3 -0.5192 -0.9819 3187092 PK04_093067 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D04 compound treatment 328880.0 -148000.0 -1.26 267240.0 -253000.0 -2.15 -2.4071 -0.9675 3187093 PK04_093068 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D05 compound treatment 410240.0 -66400.0 -0.57 272510.0 -248000.0 -2.1 -1.886 -0.8665 3068220 PK04_093069 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D06 compound treatment 220800.0 -256000.0 -2.18 217470.0 -303000.0 -2.57 -3.3558 -0.9966 3187094 PK04_093070 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D07 compound treatment 429180.0 -47500.0 -0.4 520760.0 446.0 0.0 -0.2831 -0.7005 3068223 PK04_093071 COC(=O)[C@H]1COC(=N1)c2ccc(OCCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D08 compound treatment 109600.0 -367000.0 -3.12 214110.0 -306000.0 -2.6 -4.0449 -0.9958 3187095 PK04_093072 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D09 compound treatment 296970.0 -180000.0 -1.53 380290.0 -140000.0 -1.19 -1.9209 -0.9922 3068225 PK04_093073 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D10 compound treatment 514780.0 38100.0 0.32 579270.0 59000.0 0.5 0.5828 0.978 3187096 PK04_093074 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D11 mock treatment 496450.0 19800.0 0.17 560160.0 39800.0 0.34 0.3579 0.9481 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D12 mock treatment 439860.0 -36800.0 -0.31 546470.0 26200.0 0.22 -0.0646 -0.1683 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D13 compound treatment 342450.0 -134000.0 -1.14 418340.0 -102000.0 -0.87 -1.4191 -0.9906 3187097 PK04_093075 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D14 compound treatment 298360.0 -178000.0 -1.52 333080.0 -187000.0 -1.59 -2.1958 -0.9997 3068228 PK04_093076 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D15 mock treatment 467410.0 -9270.0 -0.08 527680.0 7370.0 0.06 -0.0116 -0.115 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D16 mock treatment 462730.0 -13900.0 -0.12 546630.0 26300.0 0.22 0.0739 0.2925 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D17 compound treatment 435370.0 -41300.0 -0.35 493600.0 -26700.0 -0.23 -0.4087 -0.9775 3187098 PK04_093077 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D18 compound treatment 362530.0 -114000.0 -0.97 402680.0 -118000.0 -1.0 -1.3923 -0.9999 3187099 PK04_093078 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D19 compound treatment 451590.0 -25100.0 -0.21 348450.0 -172000.0 -1.46 -1.1818 -0.8021 3068229 PK04_093079 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D20 compound treatment 419700.0 -57000.0 -0.48 451060.0 -69300.0 -0.59 -0.7582 -0.9954 3187100 PK04_093080 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D21 compound treatment 392320.0 -84400.0 -0.72 383560.0 -137000.0 -1.16 -1.3277 -0.9734 3068232 PK04_093081 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D22 compound treatment 418590.0 -58100.0 -0.49 481040.0 -39300.0 -0.33 -0.585 -0.9816 3187101 PK04_093082 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D23 compound treatment 406810.0 -69900.0 -0.59 380680.0 -140000.0 -1.18 -1.2579 -0.9491 3187102 PK04_093083 COC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 D24 compound treatment 321650.0 -155000.0 -1.32 353930.0 -166000.0 -1.41 -1.9306 -0.9994 3068234 PK04_093084 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E01 mock treatment 304210.0 -172000.0 -1.47 340030.0 -180000.0 -1.53 -2.1189 -0.9998 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E02 mock treatment 496960.0 20300.0 0.17 476670.0 -43600.0 -0.37 -0.1398 -0.3422 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E03 compound treatment 425280.0 -51400.0 -0.44 455530.0 -64800.0 -0.55 -0.6978 -0.9936 3187103 PK04_093085 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E04 compound treatment 212800.0 -264000.0 -2.24 232360.0 -288000.0 -2.44 -3.3146 -0.9991 3187104 PK04_093086 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E05 compound treatment 549280.0 72600.0 0.62 559700.0 39400.0 0.33 0.673 0.9584 3068237 PK04_093087 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E06 compound treatment 432330.0 -44300.0 -0.38 495520.0 -24800.0 -0.21 -0.4155 -0.9619 3187105 PK04_093088 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E07 compound treatment 333890.0 -143000.0 -1.21 290400.0 -230000.0 -1.95 -2.238 -0.974 3068240 PK04_093089 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E08 compound treatment 287590.0 -189000.0 -1.61 302890.0 -217000.0 -1.84 -2.4416 -0.9977 3187106 PK04_093090 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E09 mock treatment 491010.0 14300.0 0.12 553410.0 33100.0 0.28 0.2847 0.9303 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E10 mock treatment 541600.0 64900.0 0.55 585210.0 64900.0 0.55 0.7798 1.0 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E11 compound treatment 384370.0 -92300.0 -0.79 433230.0 -87100.0 -0.74 -1.0776 -0.9995 3068242 PK04_093091 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E12 compound treatment 322940.0 -154000.0 -1.31 307690.0 -213000.0 -1.8 -2.2002 -0.9875 3187107 PK04_093092 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E13 compound treatment 404030.0 -72600.0 -0.62 482450.0 -37900.0 -0.32 -0.6641 -0.9535 3068264 PK04_093093 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E14 compound treatment 322850.0 -154000.0 -1.31 321060.0 -199000.0 -1.69 -2.1205 -0.992 3187108 PK04_093094 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E15 compound treatment 415680.0 -61000.0 -0.52 421610.0 -98700.0 -0.84 -0.959 -0.9735 3187109 PK04_093095 COC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E16 compound treatment 263960.0 -213000.0 -1.81 404970.0 -115000.0 -0.98 -1.9715 -0.9583 3068267 PK04_093096 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E17 mock treatment 391970.0 -84700.0 -0.72 468540.0 -51800.0 -0.44 -0.8201 -0.9718 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E18 mock treatment 485440.0 8760.0 0.07 556960.0 36600.0 0.31 0.2725 0.8525 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E19 compound treatment 500060.0 23400.0 0.2 565930.0 45600.0 0.39 0.4143 0.9522 3187110 PK04_093097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E20 compound treatment 358000.0 -119000.0 -1.01 254240.0 -266000.0 -2.26 -2.3099 -0.9342 3187111 PK04_093098 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E21 compound treatment 474470.0 -2210.0 -0.02 506290.0 -14000.0 -0.12 -0.0974 -0.8088 3068269 PK04_093099 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E22 compound treatment 379430.0 -97200.0 -0.83 306420.0 -214000.0 -1.81 -1.868 -0.9367 3187184 PK04_093100 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E23 compound treatment 406690.0 -70000.0 -0.6 286350.0 -234000.0 -1.98 -1.8244 -0.8805 3068272 PK04_093101 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 E24 compound treatment 397380.0 -79300.0 -0.67 310420.0 -210000.0 -1.78 -1.736 -0.9118 3187185 PK04_093102 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F01 mock treatment 456210.0 -20500.0 -0.17 496850.0 -23500.0 -0.2 -0.2639 -0.9978 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F02 mock treatment 468250.0 -8430.0 -0.07 502040.0 -18300.0 -0.16 -0.1603 -0.9386 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F03 compound treatment 332010.0 -145000.0 -1.23 425400.0 -94900.0 -0.81 -1.4396 -0.9788 3068274 PK04_093103 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F04 compound treatment 330720.0 -146000.0 -1.24 279740.0 -241000.0 -2.04 -2.321 -0.9716 3187186 PK04_093104 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F05 compound treatment 208990.0 -268000.0 -2.28 232440.0 -288000.0 -2.44 -3.337 -0.9994 3068276 PK04_093105 COC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F06 compound treatment 416030.0 -60600.0 -0.52 439220.0 -81100.0 -0.69 -0.8513 -0.99 3187187 PK04_093106 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F07 compound treatment 396100.0 -80600.0 -0.69 437880.0 -82400.0 -0.7 -0.9792 -1.0 3187188 PK04_093107 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F08 compound treatment 434350.0 -42300.0 -0.36 327590.0 -193000.0 -1.63 -1.4106 -0.8427 3068278 PK04_093108 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F09 mock treatment 540710.0 64000.0 0.54 521960.0 1650.0 0.01 0.3951 0.725 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F10 mock treatment 541290.0 64600.0 0.55 561550.0 41200.0 0.35 0.636 0.9762 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F11 compound treatment 424640.0 -52000.0 -0.44 413170.0 -107000.0 -0.91 -0.9557 -0.9454 3187189 PK04_093109 COC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F12 compound treatment 456750.0 -19900.0 -0.17 455360.0 -65000.0 -0.55 -0.5095 -0.8838 3068280 PK04_093110 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F13 compound treatment 317280.0 -159000.0 -1.36 307010.0 -213000.0 -1.81 -2.2383 -0.9899 3187190 PK04_093111 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F14 compound treatment 328500.0 -148000.0 -1.26 415160.0 -105000.0 -0.89 -1.5221 -0.9857 3187191 PK04_093112 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F15 compound treatment 237490.0 -239000.0 -2.03 304070.0 -216000.0 -1.83 -2.7359 -0.9987 3068282 PK04_093113 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F16 compound treatment 305540.0 -171000.0 -1.46 393890.0 -126000.0 -1.07 -1.7878 -0.9887 3187192 PK04_093114 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F17 mock treatment 479650.0 2970.0 0.03 552280.0 32000.0 0.27 0.2096 0.7697 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F18 mock treatment 542370.0 65700.0 0.56 527520.0 7210.0 0.06 0.4384 0.7798 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F19 compound treatment 226160.0 -251000.0 -2.13 293060.0 -227000.0 -1.93 -2.8701 -0.9987 3187193 PK04_093115 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F20 compound treatment 541660.0 65000.0 0.55 465640.0 -54700.0 -0.46 0.063 0.0872 3068312 PK04_093116 NC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F21 compound treatment 429660.0 -47000.0 -0.4 356710.0 -164000.0 -1.39 -1.2642 -0.8753 3068314 PK04_093117 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F22 compound treatment 540000.0 63300.0 0.54 534140.0 13800.0 0.12 0.4638 0.8413 3187194 PK04_093118 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F23 compound treatment 284130.0 -193000.0 -1.64 311840.0 -208000.0 -1.77 -2.4088 -0.9993 3187195 PK04_093119 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 F24 compound treatment 370400.0 -106000.0 -0.9 489160.0 -31200.0 -0.26 -0.8262 -0.8771 3068317 PK04_093120 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G01 compound treatment 406630.0 -70000.0 -0.6 444120.0 -76200.0 -0.65 -0.8784 -0.9992 3187196 PK04_093121 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G02 compound treatment 462330.0 -14300.0 -0.12 420420.0 -99900.0 -0.85 -0.6855 -0.8007 3068319 PK04_093122 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCCCC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G03 mock treatment 494960.0 18300.0 0.16 512550.0 -7760.0 -0.07 0.0634 0.3754 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G04 mock treatment 519970.0 43300.0 0.37 438040.0 -82300.0 -0.7 -0.2331 -0.2954 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G05 compound treatment 511090.0 34400.0 0.29 481150.0 -39200.0 -0.33 -0.0279 -0.063 3187197 PK04_093123 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G06 compound treatment 395420.0 -81300.0 -0.69 235900.0 -284000.0 -2.41 -2.1948 -0.8745 3187198 PK04_093124 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G07 compound treatment 501500.0 24800.0 0.21 519680.0 -634.0 -0.01 0.1455 0.6889 3068323 PK04_093125 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G08 compound treatment 468480.0 -8200.0 -0.07 444020.0 -76300.0 -0.65 -0.5069 -0.7788 3187199 PK04_093126 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G09 compound treatment 485540.0 8860.0 0.08 373020.0 -147000.0 -1.25 -0.8302 -0.6632 3068325 PK04_093127 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G10 compound treatment 304000.0 -173000.0 -1.47 352250.0 -168000.0 -1.43 -2.0468 -0.9999 3187200 PK04_093128 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G11 compound treatment 451750.0 -24900.0 -0.21 389010.0 -131000.0 -1.11 -0.9375 -0.8269 3187201 PK04_093129 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G12 compound treatment 182120.0 -295000.0 -2.51 270160.0 -250000.0 -2.12 -3.2724 -0.9966 3068327 PK04_093130 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G13 compound treatment 333870.0 -143000.0 -1.21 351930.0 -168000.0 -1.43 -1.8691 -0.9968 3187202 PK04_093131 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G14 compound treatment 477790.0 1110.0 0.01 487260.0 -33100.0 -0.28 -0.1916 -0.6829 3187203 PK04_093132 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G15 compound treatment 457560.0 -19100.0 -0.16 540330.0 20000.0 0.17 0.005 0.0215 3068330 PK04_093133 COC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G16 compound treatment 333920.0 -143000.0 -1.21 330430.0 -190000.0 -1.61 -1.9977 -0.9903 3068332 PK04_093134 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G17 compound treatment 441310.0 -35400.0 -0.3 491000.0 -29300.0 -0.25 -0.3886 -0.9955 3187278 PK04_093135 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G18 compound treatment 369360.0 -107000.0 -0.91 357440.0 -163000.0 -1.38 -1.6225 -0.9798 3187279 PK04_093136 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G19 mock treatment 535840.0 59200.0 0.5 559370.0 39100.0 0.33 0.5902 0.9794 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G20 mock treatment 485250.0 8570.0 0.07 395580.0 -125000.0 -1.06 -0.6966 -0.6568 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G21 compound treatment 507630.0 31000.0 0.26 582170.0 61900.0 0.52 0.5572 0.9491 3187280 PK04_093137 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G22 compound treatment 299790.0 -177000.0 -1.5 376810.0 -144000.0 -1.22 -1.9249 -0.9945 3068361 PK04_093138 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G23 compound treatment 392560.0 -84100.0 -0.72 500900.0 -19400.0 -0.16 -0.6225 -0.8477 3187281 PK04_093139 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 G24 compound treatment 327890.0 -149000.0 -1.27 312540.0 -208000.0 -1.76 -2.1413 -0.9868 3187282 PK04_093140 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H01 compound treatment 218120.0 -259000.0 -2.2 170040.0 -350000.0 -2.97 -3.6564 -0.989 3068365 PK04_093141 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H02 compound treatment 347290.0 -129000.0 -1.1 376900.0 -143000.0 -1.22 -1.6386 -0.9988 3187283 PK04_093142 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H03 mock treatment 554800.0 78100.0 0.66 459720.0 -60600.0 -0.51 0.1065 0.1267 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H04 mock treatment 449210.0 -27500.0 -0.23 558720.0 38400.0 0.33 0.0651 0.1624 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H05 compound treatment 333290.0 -143000.0 -1.22 347560.0 -173000.0 -1.47 -1.8988 -0.9958 3068368 PK04_093143 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H06 compound treatment 448010.0 -28700.0 -0.24 451750.0 -68600.0 -0.58 -0.5837 -0.9255 3187284 PK04_093144 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H07 compound treatment 359690.0 -117000.0 -1.0 283040.0 -237000.0 -2.01 -2.127 -0.9473 3187285 PK04_093145 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H08 compound treatment 501990.0 25300.0 0.22 485290.0 -35000.0 -0.3 -0.0578 -0.1576 3068370 PK04_093146 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H09 compound treatment 262020.0 -215000.0 -1.83 426260.0 -94100.0 -0.8 -1.8554 -0.9311 3187286 PK04_093147 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H10 compound treatment 379680.0 -97000.0 -0.83 345350.0 -175000.0 -1.48 -1.633 -0.9616 3187287 PK04_093148 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H11 compound treatment 417240.0 -59400.0 -0.51 319290.0 -201000.0 -1.71 -1.5633 -0.879 3068373 PK04_093149 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H12 compound treatment 399790.0 -76900.0 -0.65 432760.0 -87600.0 -0.74 -0.9877 -0.998 3187288 PK04_093150 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H13 compound treatment 377800.0 -98900.0 -0.84 405630.0 -115000.0 -0.97 -1.2827 -0.9974 3187289 PK04_093151 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H14 compound treatment 290920.0 -186000.0 -1.58 280160.0 -240000.0 -2.04 -2.5579 -0.9921 3068375 PK04_093152 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H15 compound treatment 277980.0 -199000.0 -1.69 408830.0 -111000.0 -0.95 -1.864 -0.9623 3187290 PK04_093153 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CC=C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H16 compound treatment 369220.0 -107000.0 -0.91 414950.0 -105000.0 -0.89 -1.2784 -0.9999 3187291 PK04_093154 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H17 compound treatment 419960.0 -56700.0 -0.48 440000.0 -80300.0 -0.68 -0.8229 -0.9857 3068378 PK04_093155 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H18 compound treatment 447580.0 -29100.0 -0.25 570130.0 49800.0 0.42 0.1238 0.2527 3187292 PK04_093156 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H19 mock treatment 538650.0 62000.0 0.53 570560.0 50200.0 0.43 0.6742 0.9944 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H20 mock treatment 514800.0 38100.0 0.32 578200.0 57900.0 0.49 0.5765 0.9797 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H21 compound treatment 285020.0 -192000.0 -1.63 269390.0 -251000.0 -2.13 -2.658 -0.9913 3187293 PK04_093157 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H22 compound treatment 341950.0 -135000.0 -1.15 327680.0 -193000.0 -1.63 -1.9659 -0.9849 3068380 PK04_093158 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H23 compound treatment 342310.0 -134000.0 -1.14 318170.0 -202000.0 -1.71 -2.0208 -0.9806 3068402 PK04_093159 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 H24 compound treatment 266620.0 -210000.0 -1.79 246530.0 -274000.0 -2.32 -2.9058 -0.9916 3187294 PK04_093160 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I01 compound treatment 335250.0 -141000.0 -1.2 428160.0 -92200.0 -0.78 -1.4035 -0.9782 3068406 PK04_093161 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I02 compound treatment 230080.0 -247000.0 -2.1 306020.0 -214000.0 -1.82 -2.7688 -0.9975 3187295 PK04_093162 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I03 compound treatment 446010.0 -30700.0 -0.26 450030.0 -70300.0 -0.6 -0.6061 -0.9313 3068409 PK04_093163 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I04 compound treatment 432920.0 -43800.0 -0.37 323780.0 -197000.0 -1.67 -1.4421 -0.8442 3187296 PK04_093164 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I05 mock treatment 483360.0 6680.0 0.06 488960.0 -31400.0 -0.27 -0.1479 -0.5437 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I06 mock treatment 502410.0 25700.0 0.22 562850.0 42500.0 0.36 0.4099 0.9713 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I07 compound treatment 296670.0 -180000.0 -1.53 306270.0 -214000.0 -1.82 -2.3667 -0.9964 3187297 PK04_093165 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I08 compound treatment 502340.0 25700.0 0.22 360690.0 -160000.0 -1.35 -0.8031 -0.5855 3068413 PK04_093166 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I09 compound treatment 524000.0 47300.0 0.4 480340.0 -40000.0 -0.34 0.0449 0.0853 3187298 PK04_093167 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I10 compound treatment 374660.0 -102000.0 -0.87 359400.0 -161000.0 -1.36 -1.5789 -0.9761 3187366 PK04_093168 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I11 compound treatment 508200.0 31500.0 0.27 526730.0 6420.0 0.05 0.2281 0.8336 3068416 PK04_093169 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I12 compound treatment 348820.0 -128000.0 -1.09 237860.0 -282000.0 -2.4 -2.4634 -0.9362 3187367 PK04_093170 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I13 compound treatment 513030.0 36400.0 0.31 566470.0 46200.0 0.39 0.4955 0.9932 3068419 PK04_093171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I14 compound treatment 414880.0 -61800.0 -0.53 365780.0 -155000.0 -1.31 -1.2987 -0.9195 3187368 PK04_093172 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I15 compound treatment 537560.0 60900.0 0.52 556210.0 35900.0 0.3 0.5815 0.9679 3068421 PK04_093173 COC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I16 compound treatment 291750.0 -185000.0 -1.57 365160.0 -155000.0 -1.32 -2.0431 -0.9961 3187369 PK04_093174 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I17 compound treatment 497550.0 20900.0 0.18 580820.0 60500.0 0.51 0.4885 0.8994 3068423 PK04_093175 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I18 compound treatment 536540.0 59900.0 0.51 503230.0 -17100.0 -0.14 0.2576 0.4866 3187370 PK04_093176 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I19 compound treatment 321350.0 -155000.0 -1.32 334030.0 -186000.0 -1.58 -2.0518 -0.996 3187371 PK04_093177 COC(=O)[C@H]1N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I20 compound treatment 302190.0 -174000.0 -1.48 344960.0 -175000.0 -1.49 -2.1015 -1.0 3068425 PK04_093178 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I21 mock treatment 533950.0 57300.0 0.49 529180.0 8870.0 0.08 0.3977 0.8067 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I22 mock treatment 488980.0 12300.0 0.1 527640.0 7330.0 0.06 0.1179 0.969 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I23 compound treatment 367450.0 -109000.0 -0.93 386400.0 -134000.0 -1.14 -1.4603 -0.995 3187372 PK04_093179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3N=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 I24 compound treatment 229940.0 -247000.0 -2.1 417850.0 -102000.0 -0.87 -2.0989 -0.9238 3068456 PK04_093180 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J01 compound treatment 181800.0 -295000.0 -2.51 309700.0 -211000.0 -1.79 -3.0372 -0.9862 3187373 PK04_093181 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J02 compound treatment 220020.0 -257000.0 -2.18 222320.0 -298000.0 -2.53 -3.3314 -0.9973 3187374 PK04_093182 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J03 compound treatment 255000.0 -222000.0 -1.89 222030.0 -298000.0 -2.53 -3.1227 -0.9895 3068460 PK04_093183 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(CC=C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J04 compound treatment 504500.0 27800.0 0.24 456640.0 -63700.0 -0.54 -0.2146 -0.3639 3187375 PK04_093184 COCCCNC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J05 mock treatment 520800.0 44100.0 0.38 494920.0 -25400.0 -0.22 0.1131 0.2613 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J06 mock treatment 507590.0 30900.0 0.26 504800.0 -15500.0 -0.13 0.0929 0.3159 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J07 compound treatment 337790.0 -139000.0 -1.18 301760.0 -219000.0 -1.85 -2.1464 -0.9763 3187376 PK04_093185 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J08 compound treatment 346360.0 -130000.0 -1.11 442640.0 -77700.0 -0.66 -1.2498 -0.9691 3068463 PK04_093186 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J09 compound treatment 457210.0 -19500.0 -0.17 419280.0 -101000.0 -0.86 -0.7231 -0.8284 3187377 PK04_093187 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J10 compound treatment 301040.0 -176000.0 -1.49 429440.0 -90900.0 -0.77 -1.6016 -0.9526 3068465 PK04_093188 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J11 compound treatment 433220.0 -43500.0 -0.37 486800.0 -33500.0 -0.28 -0.4625 -0.9916 3187378 PK04_093189 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J12 compound treatment 475890.0 -789.0 -0.01 431460.0 -88900.0 -0.75 -0.5377 -0.7134 3068467 PK04_093190 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J13 compound treatment 311720.0 -165000.0 -1.4 213470.0 -307000.0 -2.6 -2.8328 -0.958 3187379 PK04_093191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J14 compound treatment 253120.0 -224000.0 -1.9 320760.0 -200000.0 -1.69 -2.5418 -0.9983 3187380 PK04_093192 COCCCNC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J15 compound treatment 424640.0 -52000.0 -0.44 526160.0 5850.0 0.05 -0.278 -0.624 3068470 PK04_093193 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J16 compound treatment 388400.0 -88300.0 -0.75 489200.0 -31100.0 -0.26 -0.7177 -0.9016 3187381 PK04_093194 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J17 compound treatment 450570.0 -26100.0 -0.22 509650.0 -10700.0 -0.09 -0.221 -0.9216 3187382 PK04_093195 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J18 compound treatment 318510.0 -158000.0 -1.35 400420.0 -120000.0 -1.02 -1.6706 -0.9905 3068473 PK04_093196 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J19 compound treatment 524800.0 48100.0 0.41 507150.0 -13200.0 -0.11 0.2105 0.4961 3187383 PK04_093197 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J20 compound treatment 351410.0 -125000.0 -1.07 352650.0 -168000.0 -1.42 -1.7592 -0.9899 3068475 PK04_093198 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J21 mock treatment 527790.0 51100.0 0.43 520690.0 376.0 0.0 0.3097 0.7123 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J22 mock treatment 494990.0 18300.0 0.16 528880.0 8570.0 0.07 0.1615 0.9397 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J23 compound treatment 392130.0 -84500.0 -0.72 428960.0 -91400.0 -0.77 -1.0566 -0.9993 3187384 PK04_093199 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(CCS(=O)(=O)c6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 J24 compound treatment 240590.0 -236000.0 -2.01 186130.0 -334000.0 -2.83 -3.4247 -0.9858 3068477 PK04_093200 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K01 compound treatment 503360.0 26700.0 0.23 539640.0 19300.0 0.16 0.2764 0.9872 3187385 PK04_093201 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K02 compound treatment 325150.0 -152000.0 -1.29 361280.0 -159000.0 -1.35 -1.8654 -0.9997 3187386 PK04_093202 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K03 compound treatment 324840.0 -152000.0 -1.29 319360.0 -201000.0 -1.7 -2.1188 -0.9906 3187447 PK04_093203 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K04 compound treatment 228890.0 -248000.0 -2.11 334330.0 -186000.0 -1.58 -2.6062 -0.9898 3068500 PK04_093204 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K05 compound treatment 408030.0 -68600.0 -0.58 420200.0 -100000.0 -0.85 -1.0135 -0.9833 3187448 PK04_093205 COC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K06 compound treatment 236720.0 -240000.0 -2.04 334490.0 -186000.0 -1.58 -2.5581 -0.9918 3187449 PK04_093206 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K07 mock treatment 538010.0 61300.0 0.52 621450.0 101000.0 0.86 0.9756 0.9716 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K08 mock treatment 474760.0 -1920.0 -0.02 601350.0 81000.0 0.69 0.4745 0.6901 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K09 compound treatment 540600.0 63900.0 0.54 575300.0 55000.0 0.47 0.7143 0.9971 3068503 PK04_093207 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K10 compound treatment 464560.0 -12100.0 -0.1 476000.0 -44300.0 -0.38 -0.3387 -0.869 3187450 PK04_093208 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K11 compound treatment 466410.0 -10300.0 -0.09 407950.0 -112000.0 -0.95 -0.7358 -0.7687 3068506 PK04_093209 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K12 compound treatment 228540.0 -248000.0 -2.11 370130.0 -150000.0 -1.27 -2.3935 -0.9708 3187451 PK04_093210 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K13 compound treatment 489670.0 13000.0 0.11 531970.0 11700.0 0.1 0.1481 0.9985 3187452 PK04_093211 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K14 compound treatment 412250.0 -64400.0 -0.55 490980.0 -29300.0 -0.25 -0.5635 -0.9362 3068509 PK04_093212 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K15 mock treatment 536920.0 60200.0 0.51 553510.0 33200.0 0.28 0.5615 0.9602 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K16 mock treatment 545870.0 69200.0 0.59 568120.0 47800.0 0.41 0.703 0.9835 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K17 compound treatment 509170.0 32500.0 0.28 524160.0 3850.0 0.03 0.2185 0.7851 3187453 PK04_093213 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K18 compound treatment 494850.0 18200.0 0.15 473810.0 -46500.0 -0.39 -0.1696 -0.4004 3187454 PK04_093214 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K19 compound treatment 407730.0 -68900.0 -0.59 285510.0 -235000.0 -1.99 -1.8232 -0.8781 3068511 PK04_093215 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K20 compound treatment 277390.0 -199000.0 -1.7 511520.0 -8790.0 -0.07 -1.2516 -0.7375 3187455 PK04_093216 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K21 compound treatment 551090.0 74400.0 0.63 498080.0 -22200.0 -0.19 0.3143 0.4758 3068513 PK04_093217 COC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K22 compound treatment 417090.0 -59600.0 -0.51 323550.0 -197000.0 -1.67 -1.5387 -0.8821 3187456 PK04_093218 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K23 mock treatment 481070.0 4390.0 0.04 556020.0 35700.0 0.3 0.2406 0.7883 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 K24 mock treatment 488390.0 11700.0 0.1 551880.0 31600.0 0.27 0.2598 0.9093 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L01 compound treatment 165070.0 -312000.0 -2.65 179610.0 -341000.0 -2.89 -3.9181 -0.9991 3187457 PK04_093219 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L02 compound treatment 164230.0 -312000.0 -2.66 289830.0 -230000.0 -1.96 -3.262 -0.9886 3068516 PK04_093220 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L03 compound treatment 178010.0 -299000.0 -2.54 198560.0 -322000.0 -2.73 -3.7266 -0.9994 3187458 PK04_093221 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L04 compound treatment 159110.0 -318000.0 -2.7 239520.0 -281000.0 -2.38 -3.5946 -0.998 3187459 PK04_093222 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L05 compound treatment 264600.0 -212000.0 -1.8 235530.0 -285000.0 -2.42 -2.984 -0.9897 3068518 PK04_093223 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L06 compound treatment 186250.0 -290000.0 -2.47 296320.0 -224000.0 -1.9 -3.0907 -0.9916 3187460 PK04_093224 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L07 mock treatment 438750.0 -37900.0 -0.32 529650.0 9340.0 0.08 -0.1722 -0.5182 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L08 mock treatment 419540.0 -57100.0 -0.49 515430.0 -4880.0 -0.04 -0.373 -0.7646 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L09 compound treatment 446730.0 -29900.0 -0.25 329780.0 -191000.0 -1.62 -1.323 -0.8086 3068520 PK04_093225 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(CC=C)C1=O)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L10 compound treatment 451640.0 -25000.0 -0.21 391200.0 -129000.0 -1.1 -0.9251 -0.8291 3187461 PK04_093226 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L11 compound treatment 305680.0 -171000.0 -1.45 320800.0 -200000.0 -1.69 -2.2254 -0.9972 3187462 PK04_093227 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L12 compound treatment 413140.0 -63500.0 -0.54 425640.0 -94700.0 -0.8 -0.9501 -0.9814 3187463 PK04_093228 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L13 compound treatment 282090.0 -195000.0 -1.66 391570.0 -129000.0 -1.09 -1.9428 -0.9796 3068543 PK04_093229 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L14 compound treatment 195520.0 -281000.0 -2.39 335250.0 -185000.0 -1.57 -2.8014 -0.9791 3187464 PK04_093230 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L15 mock treatment 502920.0 26200.0 0.22 567100.0 46800.0 0.4 0.4385 0.963 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L16 mock treatment 482750.0 6070.0 0.05 530740.0 10400.0 0.09 0.0991 0.9672 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L17 compound treatment 450400.0 -26300.0 -0.22 464490.0 -55800.0 -0.47 -0.4929 -0.9413 3068545 PK04_093231 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L18 compound treatment 270580.0 -206000.0 -1.75 471780.0 -48500.0 -0.41 -1.5309 -0.85 3187465 PK04_093232 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L19 compound treatment 451570.0 -25100.0 -0.21 493550.0 -26800.0 -0.23 -0.3116 -0.9995 3187466 PK04_093233 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L20 compound treatment 457190.0 -19500.0 -0.17 487690.0 -32600.0 -0.28 -0.3129 -0.97 3068547 PK04_093234 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L21 compound treatment 423740.0 -52900.0 -0.45 444320.0 -76000.0 -0.64 -0.7743 -0.9846 3187467 PK04_093235 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(CC=C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L22 compound treatment 328400.0 -148000.0 -1.26 420920.0 -99400.0 -0.84 -1.4882 -0.9808 3068549 PK04_093236 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L23 mock treatment 443950.0 -32700.0 -0.28 538650.0 18300.0 0.16 -0.0869 -0.2725 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 L24 mock treatment 429620.0 -47100.0 -0.4 442200.0 -78100.0 -0.66 -0.7516 -0.9709 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M01 compound treatment 191920.0 -285000.0 -2.42 174050.0 -346000.0 -2.94 -3.7899 -0.9954 3187528 PK04_093237 COC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M02 compound treatment 193190.0 -283000.0 -2.41 253140.0 -267000.0 -2.27 -3.3079 -0.9995 3187529 PK04_093238 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M03 compound treatment 234660.0 -242000.0 -2.06 425130.0 -95200.0 -0.81 -2.0268 -0.9165 3068551 PK04_093239 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M04 compound treatment 329200.0 -147000.0 -1.25 476930.0 -43400.0 -0.37 -1.1474 -0.8775 3187530 PK04_093240 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M05 compound treatment 407530.0 -69100.0 -0.59 510630.0 -9680.0 -0.08 -0.4741 -0.7981 3068553 PK04_093241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M06 compound treatment 339710.0 -137000.0 -1.17 352480.0 -168000.0 -1.42 -1.8306 -0.9951 3187531 PK04_093242 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M07 compound treatment 484410.0 7730.0 0.07 481520.0 -38800.0 -0.33 -0.1862 -0.5548 3187532 PK04_093243 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M08 compound treatment 365280.0 -111000.0 -0.95 294280.0 -226000.0 -1.92 -2.0259 -0.9472 3068555 PK04_093244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M09 mock treatment 496640.0 20000.0 0.17 534960.0 14600.0 0.12 0.2079 0.9882 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M10 mock treatment 480750.0 4070.0 0.03 458920.0 -61400.0 -0.52 -0.3438 -0.6586 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M11 compound treatment 471010.0 -5670.0 -0.05 532360.0 12000.0 0.1 0.0382 0.3377 3187533 PK04_093245 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M12 compound treatment 341970.0 -135000.0 -1.15 483320.0 -37000.0 -0.31 -1.0322 -0.8688 3187534 PK04_093246 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M13 mock treatment 427120.0 -49600.0 -0.42 559840.0 39500.0 0.34 -0.061 -0.1133 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M14 mock treatment 483280.0 6600.0 0.06 561140.0 40800.0 0.35 0.2846 0.8112 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M15 compound treatment 491440.0 14800.0 0.13 466470.0 -53800.0 -0.46 -0.2342 -0.4944 3068558 PK04_093247 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M16 compound treatment 524840.0 48200.0 0.41 321770.0 -199000.0 -1.68 -0.9012 -0.5199 3187535 PK04_093248 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M17 compound treatment 466400.0 -10300.0 -0.09 495230.0 -25100.0 -0.21 -0.2123 -0.9228 3068560 PK04_093249 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M18 compound treatment 289070.0 -188000.0 -1.6 480420.0 -39900.0 -0.34 -1.3679 -0.8384 3187536 PK04_093250 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M19 compound treatment 516510.0 39800.0 0.34 558820.0 38500.0 0.33 0.4706 0.9998 3187537 PK04_093251 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M20 compound treatment 481250.0 4570.0 0.04 464160.0 -56200.0 -0.48 -0.3093 -0.6472 3068562 PK04_093252 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)N3CCOCC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M21 compound treatment 453560.0 -23100.0 -0.2 498250.0 -22100.0 -0.19 -0.2714 -0.9997 3068586 PK04_093253 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M22 compound treatment 408280.0 -68400.0 -0.58 494580.0 -25700.0 -0.22 -0.5658 -0.9104 3187538 PK04_093254 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M23 compound treatment 89080.0 -388000.0 -3.3 177720.0 -343000.0 -2.91 -4.3866 -0.998 3068589 PK04_093255 COC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 M24 compound treatment 269760.0 -207000.0 -1.76 327250.0 -193000.0 -1.64 -2.4028 -0.9993 3187539 PK04_093256 NC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N01 compound treatment 168600.0 -308000.0 -2.62 227900.0 -292000.0 -2.48 -3.6072 -0.9996 3187540 PK04_093257 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N02 compound treatment 307540.0 -169000.0 -1.44 220040.0 -300000.0 -2.55 -2.8186 -0.9635 3187541 PK04_093258 CN(C)C(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N03 compound treatment 156050.0 -321000.0 -2.73 252320.0 -268000.0 -2.27 -3.5362 -0.9959 3068594 PK04_093259 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(CC=C)C3=O)[C@@H](O2)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N04 compound treatment 325830.0 -151000.0 -1.28 510510.0 -9800.0 -0.08 -0.9662 -0.7514 3187542 PK04_093260 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N05 compound treatment 221540.0 -255000.0 -2.17 430500.0 -89800.0 -0.76 -2.0735 -0.9014 3068597 PK04_093261 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(CC=C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N06 compound treatment 428380.0 -48300.0 -0.41 234180.0 -286000.0 -2.43 -2.0068 -0.8152 3187543 PK04_093262 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N07 compound treatment 318990.0 -158000.0 -1.34 347160.0 -173000.0 -1.47 -1.9872 -0.999 3187544 PK04_093263 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(CC=C)C3=O)[C@H](O2)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N08 compound treatment 239870.0 -237000.0 -2.01 325330.0 -195000.0 -1.65 -2.5941 -0.9952 3068600 PK04_093264 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N09 mock treatment 477200.0 521.0 0.0 537720.0 17400.0 0.15 0.1075 0.728 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N10 mock treatment 479710.0 3030.0 0.03 506910.0 -13400.0 -0.11 -0.0622 -0.5332 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N11 compound treatment 81950.0 -395000.0 -3.36 112960.0 -407000.0 -3.46 -4.8179 -0.9999 3187545 PK04_093265 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N12 compound treatment 372440.0 -104000.0 -0.89 254250.0 -266000.0 -2.26 -2.223 -0.9167 3187546 PK04_093266 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N13 mock treatment 497670.0 21000.0 0.18 537570.0 17300.0 0.15 0.2298 0.9951 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N14 mock treatment 499580.0 22900.0 0.19 551630.0 31300.0 0.27 0.3256 0.9884 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N15 compound treatment 294130.0 -183000.0 -1.55 319690.0 -201000.0 -1.7 -2.3015 -0.999 3068603 PK04_093267 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(CCS(=O)(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N16 compound treatment 382500.0 -94200.0 -0.8 469660.0 -50700.0 -0.43 -0.8704 -0.9573 3187547 PK04_093268 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N17 compound treatment 374240.0 -102000.0 -0.87 363650.0 -157000.0 -1.33 -1.5559 -0.9791 3068605 PK04_093269 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N18 compound treatment 329280.0 -147000.0 -1.25 405210.0 -115000.0 -0.98 -1.5771 -0.9923 3187548 PK04_093270 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N19 compound treatment 325350.0 -151000.0 -1.29 377790.0 -143000.0 -1.21 -1.7652 -0.9995 3068607 PK04_093271 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(CC=C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N20 compound treatment 371780.0 -105000.0 -0.89 423040.0 -97300.0 -0.83 -1.2145 -0.9992 3186297 PK04_093272 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N21 compound treatment 355400.0 -121000.0 -1.03 377400.0 -143000.0 -1.21 -1.5868 -0.9968 3186298 PK04_093273 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CC=C)C3=O)[C@@H](O2)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N22 compound treatment 442100.0 -34600.0 -0.29 476050.0 -44300.0 -0.38 -0.4735 -0.9927 3068610 PK04_093274 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N23 compound treatment 232650.0 -244000.0 -2.08 262660.0 -258000.0 -2.19 -3.0134 -0.9997 3068635 PK04_093275 CC(=O)N1Cc2ccccc2C[C@]3(N=C(O[C@@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 N24 compound treatment 251570.0 -225000.0 -1.92 397760.0 -123000.0 -1.04 -2.0893 -0.9588 3186299 PK04_093276 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O01 compound treatment 205680.0 -271000.0 -2.31 211870.0 -308000.0 -2.62 -3.4803 -0.998 3068638 PK04_093277 COC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O02 compound treatment 111110.0 -366000.0 -3.11 170460.0 -350000.0 -2.97 -4.2976 -0.9997 3186300 PK04_093278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O03 compound treatment 140570.0 -336000.0 -2.86 122650.0 -398000.0 -3.37 -4.4071 -0.9966 3068640 PK04_093279 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O04 compound treatment 260000.0 -217000.0 -1.84 371740.0 -149000.0 -1.26 -2.1946 -0.9828 3186301 PK04_093280 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O05 compound treatment 362900.0 -114000.0 -0.97 377500.0 -143000.0 -1.21 -1.5411 -0.9938 3068642 PK04_093281 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O06 compound treatment 341650.0 -135000.0 -1.15 326080.0 -194000.0 -1.65 -1.9773 -0.9845 3186302 PK04_093282 COCCCNC(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O07 compound treatment 404030.0 -72600.0 -0.62 481490.0 -38800.0 -0.33 -0.6699 -0.9566 3186303 PK04_093283 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O08 compound treatment 218800.0 -258000.0 -2.19 169780.0 -351000.0 -2.97 -3.6539 -0.9888 3068645 PK04_093284 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O09 compound treatment 97280.0 -379000.0 -3.23 77920.0 -442000.0 -3.75 -4.9359 -0.9972 3186304 PK04_093285 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O10 compound treatment 252730.0 -224000.0 -1.91 267280.0 -253000.0 -2.15 -2.8649 -0.9982 3186305 PK04_093286 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O11 mock treatment 428640.0 -48000.0 -0.41 309440.0 -211000.0 -1.79 -1.5538 -0.8468 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O12 mock treatment 428200.0 -48500.0 -0.41 436480.0 -83800.0 -0.71 -0.7945 -0.9664 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O13 compound treatment 282970.0 -194000.0 -1.65 396710.0 -124000.0 -1.05 -1.9067 -0.9762 3068648 PK04_093287 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O14 compound treatment 310020.0 -167000.0 -1.42 372120.0 -148000.0 -1.26 -1.8914 -0.9982 3186306 PK04_093288 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O15 compound treatment 348910.0 -128000.0 -1.09 423140.0 -97200.0 -0.82 -1.3515 -0.9907 3068650 PK04_093289 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O16 compound treatment 264820.0 -212000.0 -1.8 282400.0 -238000.0 -2.02 -2.7015 -0.9984 3186307 PK04_093290 CN(C)C(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O17 compound treatment 368320.0 -108000.0 -0.92 404340.0 -116000.0 -0.98 -1.3475 -0.9995 3186308 PK04_093291 COC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O18 compound treatment 258690.0 -218000.0 -1.85 245810.0 -275000.0 -2.33 -2.9579 -0.9936 3068652 PK04_093292 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O19 compound treatment 307610.0 -169000.0 -1.44 294720.0 -226000.0 -1.91 -2.3702 -0.9901 3186309 PK04_093293 COC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O20 compound treatment 317540.0 -159000.0 -1.35 287520.0 -233000.0 -1.97 -2.3537 -0.983 3068654 PK04_093294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O21 compound treatment 139950.0 -337000.0 -2.86 121510.0 -399000.0 -3.38 -4.4177 -0.9966 3186310 PK04_093295 COC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O22 compound treatment 217000.0 -260000.0 -2.21 334570.0 -186000.0 -1.58 -2.6762 -0.9863 3186311 PK04_093296 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O23 compound treatment 251840.0 -225000.0 -1.91 271040.0 -249000.0 -2.11 -2.8477 -0.9987 3068656 PK04_093297 COC(=O)[C@@H]1N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 O24 compound treatment 82040.0 -395000.0 -3.36 196960.0 -323000.0 -2.74 -4.3135 -0.995 3186312 PK04_093298 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P01 compound treatment 70960.0 -406000.0 -3.45 103650.0 -417000.0 -3.53 -4.9399 -0.9999 3186313 PK04_093299 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(CCS(=O)(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P02 compound treatment 74350.0 -402000.0 -3.42 74780.0 -446000.0 -3.78 -5.0926 -0.9988 3186314 PK04_093300 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P03 compound treatment 104230.0 -372000.0 -3.17 75810.0 -445000.0 -3.77 -4.9067 -0.9963 3067960 PK04_093301 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P04 compound treatment 47600.0 -429000.0 -3.65 38330.0 -482000.0 -4.09 -5.4722 -0.9984 3186315 PK04_093302 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P05 compound treatment 94970.0 -382000.0 -3.25 130610.0 -390000.0 -3.31 -4.6337 -1.0 3186316 PK04_093303 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4N(CC=C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P06 compound treatment 75230.0 -401000.0 -3.42 146040.0 -374000.0 -3.17 -4.6599 -0.9993 3067963 PK04_093304 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P07 compound treatment 146290.0 -330000.0 -2.81 213510.0 -307000.0 -2.6 -3.8277 -0.9993 3186317 PK04_093305 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(CC=C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P08 compound treatment 134480.0 -342000.0 -2.91 190620.0 -330000.0 -2.8 -4.0361 -0.9998 3186362 PK04_093306 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P09 compound treatment 134080.0 -343000.0 -2.91 129850.0 -390000.0 -3.31 -4.403 -0.998 3067965 PK04_093307 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CCS(=O)(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P10 compound treatment 173920.0 -303000.0 -2.58 196190.0 -324000.0 -2.75 -3.7654 -0.9995 3186363 PK04_093308 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P11 mock treatment 283050.0 -194000.0 -1.65 326040.0 -194000.0 -1.65 -2.3301 -1.0 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P12 mock treatment 320830.0 -156000.0 -1.33 293360.0 -227000.0 -1.93 -2.2988 -0.9834 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P13 compound treatment 134950.0 -342000.0 -2.91 128320.0 -392000.0 -3.33 -4.4069 -0.9978 3186364 PK04_093309 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(CCS(=O)(=O)c6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P14 compound treatment 239900.0 -237000.0 -2.01 204710.0 -316000.0 -2.68 -3.3174 -0.9902 3067968 PK04_093310 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P15 compound treatment 108550.0 -368000.0 -3.13 174300.0 -346000.0 -2.94 -4.29 -0.9995 3186365 PK04_093311 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(CC=C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P16 compound treatment 274200.0 -202000.0 -1.72 251520.0 -269000.0 -2.28 -2.8303 -0.9904 3186366 PK04_093312 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P17 compound treatment 141780.0 -335000.0 -2.85 167400.0 -353000.0 -2.99 -4.1315 -0.9997 3067970 PK04_093313 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(CC=C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P18 compound treatment 164110.0 -313000.0 -2.66 152730.0 -368000.0 -3.12 -4.0851 -0.9969 3186367 PK04_093314 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P19 compound treatment 146880.0 -330000.0 -2.81 134320.0 -386000.0 -3.27 -4.2992 -0.997 3067972 PK04_093315 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(CC=C)C3=O)[C@H](O2)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P20 compound treatment 136830.0 -340000.0 -2.89 187930.0 -332000.0 -2.82 -4.0381 -0.9999 3186368 PK04_093316 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P21 compound treatment 85170.0 -392000.0 -3.33 114730.0 -406000.0 -3.44 -4.7879 -0.9999 3067974 PK04_093317 CC(=O)N1Cc2ccccc2C[C@@]3(N=C(O[C@H]3c4ccccc4)c5ccc(OCCCO)cc5)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P22 compound treatment 256320.0 -220000.0 -1.87 286910.0 -233000.0 -1.98 -2.7256 -0.9996 3186369 PK04_093318 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P23 compound treatment 144430.0 -332000.0 -2.83 256980.0 -263000.0 -2.23 -3.5782 -0.9932 3067976 PK04_093319 CC(=O)N1Cc2ccccc2C[C@@]3(COC(=N3)c4ccc(OCCCO)cc4)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2093 P24 compound treatment 31650.0 -445000.0 -3.79 63940.0 -456000.0 -3.87 -5.4145 -0.9999 3186370 PK04_093320 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A01 compound treatment 304540.0 -233000.0 -1.98 308770.0 -192000.0 -1.63 -2.5518 -0.9952 3186371 PK04_094001 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A02 compound treatment 201180.0 -336000.0 -2.86 206140.0 -294000.0 -2.5 -3.7892 -0.9977 3067979 PK04_094002 COCCCNC(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A03 compound treatment 354010.0 -183000.0 -1.56 383390.0 -117000.0 -0.99 -1.8066 -0.9763 3068002 PK04_094003 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A04 compound treatment 433780.0 -104000.0 -0.88 424080.0 -76500.0 -0.65 -1.0827 -0.9886 3186372 PK04_094004 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A05 compound treatment 362400.0 -175000.0 -1.49 414810.0 -85800.0 -0.73 -1.5677 -0.9457 3068007 PK04_094005 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A06 compound treatment 364420.0 -173000.0 -1.47 312750.0 -188000.0 -1.59 -2.1677 -0.9992 3186373 PK04_094006 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A07 compound treatment 380640.0 -157000.0 -1.33 350590.0 -150000.0 -1.27 -1.8432 -0.9997 3186374 PK04_094007 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A08 compound treatment 369870.0 -168000.0 -1.43 333820.0 -167000.0 -1.41 -2.0086 -1.0 3068010 PK04_094008 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A09 compound treatment 500020.0 -37500.0 -0.32 299420.0 -201000.0 -1.71 -1.432 -0.8249 3186375 PK04_094009 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A10 compound treatment 330210.0 -207000.0 -1.76 282960.0 -218000.0 -1.85 -2.5522 -0.9997 3068013 PK04_094010 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A11 compound treatment 283580.0 -254000.0 -2.16 255010.0 -246000.0 -2.08 -3.0004 -0.9998 3186376 PK04_094011 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A12 compound treatment 206810.0 -331000.0 -2.81 173820.0 -327000.0 -2.77 -3.9492 -1.0 3186377 PK04_094012 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A13 mock treatment 536850.0 -623.0 -0.01 374880.0 -126000.0 -1.07 -0.7578 -0.7106 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A14 mock treatment 394240.0 -143000.0 -1.22 462560.0 -38000.0 -0.32 -1.0898 -0.8645 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A15 compound treatment 332510.0 -205000.0 -1.74 363210.0 -137000.0 -1.17 -2.057 -0.9808 3068016 PK04_094013 CN(C)C(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A16 compound treatment 420000.0 -117000.0 -1.0 266900.0 -234000.0 -1.98 -2.1084 -0.9497 3186378 PK04_094014 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A17 compound treatment 475520.0 -62000.0 -0.53 451450.0 -49100.0 -0.42 -0.6674 -0.9933 3068018 PK04_094015 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A18 compound treatment 312660.0 -225000.0 -1.91 340080.0 -161000.0 -1.36 -2.3152 -0.9861 3186379 PK04_094016 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A19 compound treatment 297850.0 -240000.0 -2.04 291420.0 -209000.0 -1.77 -2.6961 -0.9976 3186380 PK04_094017 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A20 compound treatment 434090.0 -103000.0 -0.88 294810.0 -206000.0 -1.75 -1.8562 -0.9496 3068020 PK04_094018 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A21 compound treatment 357730.0 -180000.0 -1.53 459780.0 -40800.0 -0.35 -1.3261 -0.8458 3186381 PK04_094019 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A22 compound treatment 526770.0 -10700.0 -0.09 422680.0 -77900.0 -0.66 -0.5317 -0.797 3186437 PK04_094020 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A23 compound treatment 419850.0 -118000.0 -1.0 290010.0 -211000.0 -1.79 -1.9707 -0.9625 3068021 PK04_094021 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 A24 compound treatment 426430.0 -111000.0 -0.94 434050.0 -66500.0 -0.56 -1.0671 -0.9697 3186438 PK04_094022 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B01 compound treatment 296800.0 -241000.0 -2.05 436650.0 -63900.0 -0.54 -1.8313 -0.8646 3186439 PK04_094023 CCCN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B02 compound treatment 444640.0 -92800.0 -0.79 405200.0 -95400.0 -0.81 -1.1306 -0.9999 3089331 PK04_094024 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B03 compound treatment 243360.0 -294000.0 -2.5 436370.0 -64200.0 -0.54 -2.1545 -0.8414 3068022 PK04_094025 CCCN1C(=O)[C@]2(Cc3ccccc13)N=C(O[C@@H]2c4ccccc4)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B04 compound treatment 325760.0 -212000.0 -1.8 401440.0 -99200.0 -0.84 -1.8683 -0.9399 3089332 PK04_094026 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B05 compound treatment 407610.0 -130000.0 -1.1 400090.0 -101000.0 -0.85 -1.384 -0.9918 3186440 PK04_094027 CCCN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B06 compound treatment 324640.0 -213000.0 -1.81 210460.0 -290000.0 -2.46 -3.0206 -0.9886 3000708 PK04_094028 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B07 compound treatment 375260.0 -162000.0 -1.38 330400.0 -170000.0 -1.44 -1.9967 -0.9997 3068023 PK04_094029 CN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B08 compound treatment 235920.0 -302000.0 -2.57 281680.0 -219000.0 -1.86 -3.1271 -0.9874 3089333 PK04_094030 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B09 compound treatment 503810.0 -33700.0 -0.29 328130.0 -172000.0 -1.46 -1.237 -0.8298 3186441 PK04_094031 CN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B10 compound treatment 259840.0 -278000.0 -2.36 208570.0 -292000.0 -2.48 -3.4217 -0.9997 3089654 PK04_094032 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B11 compound treatment 221760.0 -316000.0 -2.69 252880.0 -248000.0 -2.1 -3.385 -0.9926 3186442 PK04_094033 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B12 compound treatment 206690.0 -331000.0 -2.81 209880.0 -291000.0 -2.47 -3.7336 -0.9978 3089334 PK04_094034 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B13 mock treatment 550080.0 12600.0 0.11 528510.0 27900.0 0.24 0.2433 0.9358 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B14 mock treatment 492030.0 -45400.0 -0.39 512670.0 12100.0 0.1 -0.2009 -0.5024 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B15 compound treatment 383150.0 -154000.0 -1.31 360270.0 -140000.0 -1.19 -1.77 -0.9988 3068024 PK04_094035 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B16 compound treatment 270560.0 -267000.0 -2.27 179360.0 -321000.0 -2.72 -3.5324 -0.9959 3000709 PK04_094036 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@H]1OC(=O)Nc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B17 compound treatment 450180.0 -87300.0 -0.74 342100.0 -158000.0 -1.34 -1.4758 -0.9609 3186443 PK04_094037 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B18 compound treatment 158300.0 -379000.0 -3.23 78630.0 -422000.0 -3.58 -4.812 -0.9987 3089363 PK04_094038 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B19 compound treatment 376010.0 -161000.0 -1.37 225280.0 -275000.0 -2.34 -2.6227 -0.968 3068025 PK04_094039 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5N(Cc6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B20 compound treatment 187940.0 -350000.0 -2.97 194170.0 -306000.0 -2.6 -3.9406 -0.9978 3089652 PK04_094040 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B21 compound treatment 512420.0 -25100.0 -0.21 296720.0 -204000.0 -1.73 -1.3736 -0.7883 3186444 PK04_094041 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B22 compound treatment 414430.0 -123000.0 -1.05 285440.0 -215000.0 -1.83 -2.0307 -0.9652 3089653 PK04_094042 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4)[C@H]1OC(=O)Nc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B23 compound treatment 306450.0 -231000.0 -1.97 380130.0 -120000.0 -1.02 -2.1123 -0.9536 3186445 PK04_094043 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 B24 compound treatment 408430.0 -129000.0 -1.1 304420.0 -196000.0 -1.66 -1.9529 -0.9796 3089657 PK04_094044 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C01 compound treatment 487770.0 -49700.0 -0.42 401600.0 -99000.0 -0.84 -0.8928 -0.9496 3068026 PK04_094045 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C02 compound treatment 393990.0 -143000.0 -1.22 360490.0 -140000.0 -1.19 -1.7035 -0.9999 3068051 PK04_094046 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C03 compound treatment 447390.0 -90100.0 -0.77 301810.0 -199000.0 -1.69 -1.7342 -0.9363 3068052 PK04_094047 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C04 compound treatment 531680.0 -5790.0 -0.05 430590.0 -70000.0 -0.59 -0.4547 -0.7632 3068053 PK04_094048 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)N3CCOCC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C05 compound treatment 419890.0 -118000.0 -1.0 297400.0 -203000.0 -1.72 -1.9261 -0.9665 3068054 PK04_094049 COCCCNC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C06 compound treatment 375110.0 -162000.0 -1.38 330580.0 -170000.0 -1.44 -1.9965 -0.9998 3186446 PK04_094050 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C07 compound treatment 430210.0 -107000.0 -0.91 417760.0 -82800.0 -0.7 -1.1421 -0.9917 3068055 PK04_094051 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C08 compound treatment 459910.0 -77600.0 -0.66 446640.0 -54000.0 -0.46 -0.7902 -0.984 3186447 PK04_094052 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C09 compound treatment 360720.0 -177000.0 -1.5 407450.0 -93100.0 -0.79 -1.622 -0.9549 3068056 PK04_094053 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C10 compound treatment 264730.0 -273000.0 -2.32 176280.0 -324000.0 -2.75 -3.586 -0.9964 3186448 PK04_094054 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C11 mock treatment 541380.0 3910.0 0.03 466470.0 -34100.0 -0.29 -0.1812 -0.6218 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C12 mock treatment 473400.0 -64100.0 -0.55 460750.0 -39800.0 -0.34 -0.6244 -0.9736 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C13 compound treatment 552400.0 14900.0 0.13 461120.0 -39500.0 -0.33 -0.147 -0.4104 3186449 PK04_094055 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C14 compound treatment 386400.0 -151000.0 -1.29 304740.0 -196000.0 -1.66 -2.0836 -0.992 3068057 PK04_094056 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C15 mock treatment 525890.0 -11600.0 -0.1 490360.0 -10200.0 -0.09 -0.1311 -0.998 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C16 mock treatment 516320.0 -21200.0 -0.18 396010.0 -105000.0 -0.89 -0.7546 -0.8336 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C17 compound treatment 474900.0 -62600.0 -0.53 329060.0 -172000.0 -1.46 -1.4053 -0.907 3186450 PK04_094057 NC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C18 compound treatment 329760.0 -208000.0 -1.77 297240.0 -203000.0 -1.72 -2.4693 -0.9999 3186451 PK04_094058 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C19 compound treatment 549630.0 12200.0 0.1 429710.0 -70900.0 -0.6 -0.352 -0.577 3068058 PK04_094059 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C20 compound treatment 325810.0 -212000.0 -1.8 289700.0 -211000.0 -1.79 -2.5382 -1.0 3186452 PK04_094060 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C21 compound treatment 461180.0 -76300.0 -0.65 428080.0 -72500.0 -0.62 -0.8939 -0.9996 3068059 PK04_094061 NC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C22 compound treatment 481830.0 -55600.0 -0.47 408870.0 -91700.0 -0.78 -0.8849 -0.9716 3186453 PK04_094062 NC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C23 compound treatment 507730.0 -29700.0 -0.25 385920.0 -115000.0 -0.97 -0.8668 -0.8623 3186454 PK04_094063 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 C24 compound treatment 497440.0 -40000.0 -0.34 494910.0 -5680.0 -0.05 -0.2749 -0.7992 3068060 PK04_094064 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D01 compound treatment 405190.0 -132000.0 -1.13 439430.0 -61200.0 -0.52 -1.1626 -0.9382 3186455 PK04_094065 CN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D02 compound treatment 300560.0 -237000.0 -2.02 304800.0 -196000.0 -1.66 -2.5996 -0.9954 3000713 PK04_094066 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D03 compound treatment 270560.0 -267000.0 -2.27 372610.0 -128000.0 -1.09 -2.3733 -0.9429 3186456 PK04_094067 CCCN1C(=O)[C@@]2(CCC(=O)OC(C)(C)C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D04 compound treatment 343470.0 -194000.0 -1.65 245030.0 -256000.0 -2.17 -2.7 -0.9909 3089658 PK04_094068 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D05 compound treatment 372650.0 -165000.0 -1.4 345280.0 -155000.0 -1.32 -1.9231 -0.9995 3068061 PK04_094069 CCCN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D06 compound treatment 314530.0 -223000.0 -1.9 324900.0 -176000.0 -1.49 -2.395 -0.9929 3089659 PK04_094070 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D07 compound treatment 409760.0 -128000.0 -1.09 335100.0 -165000.0 -1.4 -1.7609 -0.992 3186457 PK04_094071 CCCN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D08 compound treatment 352980.0 -184000.0 -1.57 306990.0 -194000.0 -1.64 -2.2711 -0.9997 3089664 PK04_094072 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D09 compound treatment 483700.0 -53800.0 -0.46 390400.0 -110000.0 -0.93 -0.9844 -0.946 3068062 PK04_094073 CCCN1C(=O)[C@@]2(CC=C)N=C(O[C@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D10 compound treatment 230400.0 -307000.0 -2.61 193760.0 -307000.0 -2.6 -3.6877 -1.0 3000714 PK04_094074 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D11 mock treatment 527550.0 -9920.0 -0.08 500380.0 -213.0 0.0 -0.061 -0.7221 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D12 mock treatment 543920.0 6450.0 0.05 510620.0 10000.0 0.09 0.0989 0.9775 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D13 compound treatment 393010.0 -144000.0 -1.23 408230.0 -92400.0 -0.78 -1.423 -0.9764 3186504 PK04_094075 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D14 compound treatment 329520.0 -208000.0 -1.77 309140.0 -191000.0 -1.62 -2.3993 -0.9991 3089660 PK04_094076 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D15 mock treatment 512810.0 -24700.0 -0.21 445050.0 -55500.0 -0.47 -0.4815 -0.9336 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D16 mock treatment 533760.0 -3710.0 -0.03 516610.0 16000.0 0.14 0.0737 0.5286 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D17 compound treatment 326270.0 -211000.0 -1.8 326400.0 -174000.0 -1.48 -2.3153 -0.9953 3186505 PK04_094077 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(Cc5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D18 compound treatment 392740.0 -145000.0 -1.23 323040.0 -178000.0 -1.51 -1.9356 -0.995 3000715 PK04_094078 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D19 compound treatment 516800.0 -20700.0 -0.18 327300.0 -173000.0 -1.47 -1.1638 -0.7861 3068063 PK04_094079 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(Cc5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D20 compound treatment 374490.0 -163000.0 -1.39 275540.0 -225000.0 -1.91 -2.3303 -0.9877 3089662 PK04_094080 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D21 compound treatment 338730.0 -199000.0 -1.69 232920.0 -268000.0 -2.27 -2.8011 -0.9895 3186506 PK04_094081 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4N(Cc5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D22 compound treatment 350510.0 -187000.0 -1.59 293290.0 -207000.0 -1.76 -2.3681 -0.9987 3000716 PK04_094082 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D23 compound treatment 437080.0 -100000.0 -0.85 442520.0 -58100.0 -0.49 -0.9523 -0.9658 3068064 PK04_094083 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 D24 compound treatment 361280.0 -176000.0 -1.5 221850.0 -279000.0 -2.36 -2.7319 -0.9758 3000811 PK04_094084 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E01 mock treatment 550570.0 13100.0 0.11 477950.0 -22600.0 -0.19 -0.057 -0.2568 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E02 mock treatment 530930.0 -6540.0 -0.06 539200.0 38600.0 0.33 0.1922 0.5786 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E03 compound treatment 442600.0 -94900.0 -0.81 471680.0 -28900.0 -0.25 -0.7441 -0.8821 3186507 PK04_094085 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E04 compound treatment 367760.0 -170000.0 -1.44 365760.0 -135000.0 -1.14 -1.8297 -0.9933 3186508 PK04_094086 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E05 compound treatment 439200.0 -98300.0 -0.84 448770.0 -51800.0 -0.44 -0.902 -0.9549 3068065 PK04_094087 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E06 compound treatment 453950.0 -83500.0 -0.71 412540.0 -88100.0 -0.75 -1.0306 -0.9997 3186509 PK04_094088 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E07 compound treatment 248610.0 -289000.0 -2.46 211060.0 -290000.0 -2.46 -3.4743 -1.0 3068066 PK04_094089 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E08 compound treatment 374510.0 -163000.0 -1.39 329280.0 -171000.0 -1.45 -2.0079 -0.9997 3186510 PK04_094090 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3N=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E09 mock treatment 530170.0 -7300.0 -0.06 408000.0 -92600.0 -0.79 -0.5993 -0.7607 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E10 mock treatment 471060.0 -66400.0 -0.56 472750.0 -27800.0 -0.24 -0.5665 -0.9251 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E11 compound treatment 307780.0 -230000.0 -1.95 321440.0 -179000.0 -1.52 -2.4563 -0.9923 3186511 PK04_094091 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E12 compound treatment 572490.0 35000.0 0.3 477690.0 -22900.0 -0.19 0.0733 0.206 3068067 PK04_094092 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E13 compound treatment 418450.0 -119000.0 -1.01 363970.0 -137000.0 -1.16 -1.5355 -0.9977 3186512 PK04_094093 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E14 compound treatment 448970.0 -88500.0 -0.75 400690.0 -99900.0 -0.85 -1.1316 -0.9983 3068068 PK04_094094 NC(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E15 compound treatment 461600.0 -75900.0 -0.65 426720.0 -73900.0 -0.63 -0.8995 -0.9999 3186513 PK04_094095 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E16 compound treatment 523400.0 -14100.0 -0.12 410880.0 -89700.0 -0.76 -0.6228 -0.8084 3068069 PK04_094096 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E17 mock treatment 569230.0 31800.0 0.27 494300.0 -6290.0 -0.05 0.1533 0.5566 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E18 mock treatment 502350.0 -35100.0 -0.3 514960.0 14400.0 0.12 -0.1251 -0.3877 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E19 compound treatment 474140.0 -63300.0 -0.54 443840.0 -56800.0 -0.48 -0.7214 -0.9984 3186514 PK04_094097 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E20 compound treatment 378470.0 -159000.0 -1.35 236860.0 -264000.0 -2.24 -2.5384 -0.971 3186515 PK04_094098 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E21 compound treatment 318960.0 -219000.0 -1.86 179010.0 -322000.0 -2.73 -3.2434 -0.9825 3068070 PK04_094099 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E22 compound treatment 390030.0 -147000.0 -1.25 358270.0 -142000.0 -1.21 -1.7406 -0.9998 3186516 PK04_094100 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E23 compound treatment 343890.0 -194000.0 -1.65 350850.0 -150000.0 -1.27 -2.0627 -0.9918 3068071 PK04_094101 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 E24 compound treatment 233010.0 -304000.0 -2.59 240770.0 -260000.0 -2.2 -3.39 -0.9968 3186517 PK04_094102 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F01 mock treatment 315760.0 -222000.0 -1.89 447550.0 -53000.0 -0.45 -1.6519 -0.8519 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F02 mock treatment 599910.0 62400.0 0.53 441340.0 -59300.0 -0.5 0.0202 0.0276 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F03 compound treatment 504420.0 -33100.0 -0.28 402670.0 -97900.0 -0.83 -0.7862 -0.8965 3068072 PK04_094103 CN1C(=O)[C@]2(CCC(=O)OC(C)(C)C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F04 compound treatment 215930.0 -322000.0 -2.74 292640.0 -208000.0 -1.76 -3.1816 -0.9775 3000813 PK04_094104 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F05 compound treatment 363750.0 -174000.0 -1.48 398370.0 -102000.0 -0.87 -1.6582 -0.9677 3186518 PK04_094105 CN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F06 compound treatment 129890.0 -408000.0 -3.47 73810.0 -427000.0 -3.62 -5.0118 -0.9998 3000814 PK04_094106 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F07 compound treatment 186910.0 -351000.0 -2.98 274300.0 -226000.0 -1.92 -3.4662 -0.9773 3186519 PK04_094107 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F08 compound treatment 160560.0 -377000.0 -3.21 161120.0 -339000.0 -2.88 -4.3036 -0.9986 3089667 PK04_094108 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F09 mock treatment 529440.0 -8030.0 -0.07 478400.0 -22200.0 -0.19 -0.1814 -0.9059 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F10 mock treatment 591040.0 53600.0 0.46 470840.0 -29800.0 -0.25 0.1438 0.276 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F11 compound treatment 295060.0 -242000.0 -2.06 344480.0 -156000.0 -1.32 -2.3946 -0.9771 3068073 PK04_094109 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F12 compound treatment 318050.0 -219000.0 -1.87 317810.0 -183000.0 -1.55 -2.4163 -0.9957 3089654 PK04_094110 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F13 compound treatment 385650.0 -152000.0 -1.29 343520.0 -157000.0 -1.33 -1.8555 -0.9999 3186520 PK04_094111 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F14 compound treatment 217320.0 -320000.0 -2.72 40500.0 -460000.0 -3.9 -4.6856 -0.9845 3089708 PK04_094112 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F15 compound treatment 320050.0 -217000.0 -1.85 271330.0 -229000.0 -1.94 -2.6831 -0.9997 3186521 PK04_094113 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@H](O2)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F16 compound treatment 176880.0 -361000.0 -3.07 118900.0 -382000.0 -3.24 -4.4586 -0.9996 3000817 PK04_094114 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F17 mock treatment 583040.0 45600.0 0.39 504420.0 3830.0 0.03 0.2971 0.7636 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F18 mock treatment 606100.0 68600.0 0.58 497560.0 -3030.0 -0.03 0.3946 0.6753 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F19 compound treatment 360590.0 -177000.0 -1.5 295530.0 -205000.0 -1.74 -2.2941 -0.9974 3068074 PK04_094115 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(Cc6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F20 compound treatment 139710.0 -398000.0 -3.38 102580.0 -398000.0 -3.38 -4.7801 -1.0 3089709 PK04_094116 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F21 compound treatment 306880.0 -231000.0 -1.96 274370.0 -226000.0 -1.92 -2.7441 -0.9999 3186522 PK04_094117 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(Cc5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F22 compound treatment 301000.0 -236000.0 -2.01 143520.0 -357000.0 -3.03 -3.5643 -0.9802 3000821 PK04_094118 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F23 compound treatment 456160.0 -81300.0 -0.69 314310.0 -186000.0 -1.58 -1.6065 -0.9313 3186523 PK04_094119 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 F24 compound treatment 94270.0 -443000.0 -3.77 441120.0 -59500.0 -0.5 -3.0228 -0.7946 3089711 PK04_094120 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G01 compound treatment 458030.0 -79400.0 -0.68 383080.0 -118000.0 -1.0 -1.1828 -0.9821 3068075 PK04_094121 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G02 compound treatment 601520.0 64000.0 0.54 521830.0 21200.0 0.18 0.5127 0.8933 3186524 PK04_094122 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)COC(=N1)c2ccc(OCCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G03 mock treatment 564640.0 27200.0 0.23 550880.0 50300.0 0.43 0.4651 0.9586 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G04 mock treatment 474040.0 -63400.0 -0.54 524120.0 23500.0 0.2 -0.2405 -0.4179 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G05 compound treatment 481170.0 -56300.0 -0.48 388880.0 -112000.0 -0.95 -1.0088 -0.9501 3186575 PK04_094123 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G06 compound treatment 315390.0 -222000.0 -1.89 259110.0 -241000.0 -2.05 -2.7844 -0.9992 3186576 PK04_094124 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G07 compound treatment 330680.0 -207000.0 -1.76 383680.0 -117000.0 -0.99 -1.9452 -0.9632 3068110 PK04_094125 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G08 compound treatment 412170.0 -125000.0 -1.07 493170.0 -7420.0 -0.06 -0.7983 -0.7476 3186577 PK04_094126 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G09 compound treatment 335110.0 -202000.0 -1.72 302600.0 -198000.0 -1.68 -2.4049 -0.9999 3068111 PK04_094127 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G10 compound treatment 446820.0 -90700.0 -0.77 386400.0 -114000.0 -0.97 -1.2303 -0.9936 3186578 PK04_094128 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G11 compound treatment 319680.0 -218000.0 -1.85 406820.0 -93800.0 -0.8 -1.8726 -0.9287 3186579 PK04_094129 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G12 compound treatment 499330.0 -38100.0 -0.32 279910.0 -221000.0 -1.87 -1.5531 -0.8175 3068112 PK04_094130 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G13 compound treatment 509120.0 -28400.0 -0.24 529570.0 29000.0 0.25 0.0033 0.0094 3186580 PK04_094131 OCCCOc1ccc(cc1)C2=N[C@](CC=C)(CO2)C(=O)NCCN3CCOCC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G14 compound treatment 391570.0 -146000.0 -1.24 339530.0 -161000.0 -1.37 -1.8438 -0.9989 3186581 PK04_094132 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G15 compound treatment 515810.0 -21700.0 -0.18 422280.0 -78300.0 -0.66 -0.6001 -0.8704 3068113 PK04_094133 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G16 compound treatment 324700.0 -213000.0 -1.81 305780.0 -195000.0 -1.65 -2.4485 -0.999 3186582 PK04_094134 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G17 compound treatment 460650.0 -76800.0 -0.65 400850.0 -99700.0 -0.85 -1.0604 -0.9919 3186583 PK04_094135 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G18 compound treatment 462720.0 -74800.0 -0.64 379840.0 -121000.0 -1.02 -1.174 -0.9737 3068114 PK04_094136 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G19 mock treatment 561120.0 23600.0 0.2 523490.0 22900.0 0.19 0.2796 0.9998 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G20 mock treatment 574240.0 36800.0 0.31 535700.0 35100.0 0.3 0.4318 0.9997 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G21 compound treatment 522500.0 -15000.0 -0.13 533440.0 32800.0 0.28 0.107 0.3491 3186584 PK04_094137 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G22 compound treatment 462980.0 -74500.0 -0.63 500390.0 -203.0 0.0 -0.4493 -0.709 3068115 PK04_094138 COCCCNC(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G23 compound treatment 505800.0 -31700.0 -0.27 440740.0 -59900.0 -0.51 -0.5495 -0.9561 3186585 PK04_094139 CN(C)C(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 G24 compound treatment 541080.0 3610.0 0.03 488340.0 -12300.0 -0.1 -0.0518 -0.4779 3186586 PK04_094140 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H01 compound treatment 281070.0 -256000.0 -2.18 274530.0 -226000.0 -1.92 -2.8984 -0.9979 3068116 PK04_094141 CCCN1C(=O)[C@]2(Cc3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H02 compound treatment 220520.0 -317000.0 -2.7 214000.0 -287000.0 -2.43 -3.6257 -0.9987 3000914 PK04_094142 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H03 mock treatment 530490.0 -6980.0 -0.06 525670.0 25100.0 0.21 0.1084 0.4909 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H04 mock treatment 546210.0 8740.0 0.07 530880.0 30300.0 0.26 0.2342 0.8758 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H05 compound treatment 326430.0 -211000.0 -1.8 346500.0 -154000.0 -1.31 -2.1938 -0.9878 3068117 PK04_094143 CCCN1C(=O)[C@]2(CC=C)N=C(O[C@@H]2c3ccccc13)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H06 compound treatment 256960.0 -281000.0 -2.39 247090.0 -254000.0 -2.15 -3.208 -0.9986 3089723 PK04_094144 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H07 compound treatment 336930.0 -201000.0 -1.71 346090.0 -155000.0 -1.31 -2.1331 -0.9915 3186589 PK04_094145 CN1C(=O)[C@@]2(Cc3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H08 compound treatment 315910.0 -222000.0 -1.88 287720.0 -213000.0 -1.81 -2.6097 -0.9998 3089724 PK04_094146 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H09 compound treatment 463840.0 -73600.0 -0.63 295690.0 -205000.0 -1.74 -1.672 -0.905 3186590 PK04_094147 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4N(C(=O)c5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H10 compound treatment 278190.0 -259000.0 -2.21 395360.0 -105000.0 -0.89 -2.1909 -0.9207 3000917 PK04_094148 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H11 compound treatment 248410.0 -289000.0 -2.46 303000.0 -198000.0 -1.68 -2.9241 -0.9825 3068119 PK04_094149 CC(C)(C)OC(=O)CC[C@]12N=C(O[C@@H]2c3ccccc3CN(C(=O)c4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H12 compound treatment 277280.0 -260000.0 -2.21 270650.0 -230000.0 -1.95 -2.9444 -0.998 3089768 PK04_094150 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H13 compound treatment 326370.0 -211000.0 -1.8 337090.0 -164000.0 -1.39 -2.2506 -0.9918 3186593 PK04_094151 OCCCOc1ccc(cc1)C2=N[C@]3(CC=C)[C@H](O2)c4ccccc4CN(C(=O)c5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H14 compound treatment 366050.0 -171000.0 -1.46 346320.0 -154000.0 -1.31 -1.9566 -0.9985 3089763 PK04_094152 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H15 compound treatment 436750.0 -101000.0 -0.86 303450.0 -197000.0 -1.67 -1.7884 -0.9518 3186594 PK04_094153 OCCCOc1ccc(cc1)C2=N[C@@]3(CCS(=O)(=O)c4ccccc4)[C@@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H16 compound treatment 401780.0 -136000.0 -1.15 277320.0 -223000.0 -1.89 -2.1555 -0.9718 3089764 PK04_094154 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3)[C@@H]1OC(=O)Nc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H17 compound treatment 515520.0 -22000.0 -0.19 493220.0 -7370.0 -0.06 -0.1763 -0.8951 3068121 PK04_094155 OCCCOc1ccc(cc1)C2=N[C@@]3(CO2)Cc4ccccc4CN(C(=O)c5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H18 compound treatment 288400.0 -249000.0 -2.12 265210.0 -235000.0 -2.0 -2.9102 -0.9996 3000919 PK04_094156 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H19 mock treatment 588170.0 50700.0 0.43 500960.0 367.0 0.0 0.3072 0.7122 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H20 mock treatment 578880.0 41400.0 0.35 519490.0 18900.0 0.16 0.3624 0.9365 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H21 compound treatment 531580.0 -5890.0 -0.05 398490.0 -102000.0 -0.87 -0.6479 -0.7468 3068122 PK04_094157 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3N(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H22 compound treatment 256700.0 -281000.0 -2.39 233890.0 -267000.0 -2.26 -3.2887 -0.9996 3089766 PK04_094158 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4)[C@@H]1OC(=O)Nc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H23 compound treatment 437660.0 -99800.0 -0.85 393800.0 -107000.0 -0.91 -1.241 -0.9995 3068123 PK04_094159 OCCCOc1ccc(cc1)C2=N[C@@]3(CC=C)[C@@H](O2)c4ccccc4CN(Cc5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 H24 compound treatment 238770.0 -299000.0 -2.54 308070.0 -193000.0 -1.63 -2.9517 -0.9771 3089769 PK04_094160 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I01 compound treatment 463040.0 -74400.0 -0.63 469540.0 -31100.0 -0.26 -0.634 -0.9245 3186651 PK04_094161 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I02 compound treatment 386120.0 -151000.0 -1.29 500160.0 -433.0 0.0 -0.9131 -0.7091 3068124 PK04_094162 COCCCNC(=O)[C@@]1(CC=C)N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I03 compound treatment 496560.0 -40900.0 -0.35 520800.0 20200.0 0.17 -0.1249 -0.3219 3186652 PK04_094163 NC(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I04 compound treatment 322530.0 -215000.0 -1.83 369570.0 -131000.0 -1.11 -2.0789 -0.9715 3068125 PK04_094164 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I05 mock treatment 505600.0 -31900.0 -0.27 521690.0 21100.0 0.18 -0.0652 -0.2007 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I06 mock treatment 508550.0 -28900.0 -0.25 556260.0 55700.0 0.47 0.1599 0.3003 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I07 compound treatment 474440.0 -63000.0 -0.54 329680.0 -171000.0 -1.45 -1.4043 -0.9085 3186653 PK04_094165 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I08 compound treatment 568960.0 31500.0 0.27 382970.0 -118000.0 -1.0 -0.5161 -0.4996 3068126 PK04_094166 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I09 compound treatment 499870.0 -37600.0 -0.32 425600.0 -75000.0 -0.64 -0.676 -0.9494 3186654 PK04_094167 COCCCNC(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I10 compound treatment 454040.0 -83400.0 -0.71 421140.0 -79500.0 -0.67 -0.9785 -0.9997 3068572 PK04_094168 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I11 compound treatment 293820.0 -244000.0 -2.07 318680.0 -182000.0 -1.54 -2.5569 -0.9894 3186655 PK04_094169 COCCCNC(=O)[C@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I12 compound treatment 342510.0 -195000.0 -1.66 280960.0 -220000.0 -1.86 -2.4902 -0.9983 3186656 PK04_094170 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I13 compound treatment 315460.0 -222000.0 -1.89 425440.0 -75200.0 -0.64 -1.7863 -0.8961 3068573 PK04_094171 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I14 compound treatment 418050.0 -119000.0 -1.02 323380.0 -177000.0 -1.5 -1.7814 -0.9818 3186657 PK04_094172 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I15 compound treatment 411040.0 -126000.0 -1.08 411530.0 -89100.0 -0.76 -1.2948 -0.9851 3068574 PK04_094173 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I16 compound treatment 320220.0 -217000.0 -1.85 392880.0 -108000.0 -0.91 -1.953 -0.9472 3186658 PK04_094174 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I17 compound treatment 464260.0 -73200.0 -0.62 326760.0 -174000.0 -1.47 -1.4831 -0.9265 3186659 PK04_094175 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I18 compound treatment 354640.0 -183000.0 -1.56 286910.0 -214000.0 -1.81 -2.3816 -0.9971 3068575 PK04_094176 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I19 compound treatment 480910.0 -56600.0 -0.48 493300.0 -7290.0 -0.06 -0.384 -0.7915 3186660 PK04_094177 CN(C)C(=O)[C@]1(CCC(=O)OC(C)(C)C)N=C(O[C@@H]1c2ccccc2)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I20 compound treatment 404400.0 -133000.0 -1.13 434460.0 -66100.0 -0.56 -1.1972 -0.9475 3068577 PK04_094178 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I21 mock treatment 544970.0 7500.0 0.06 559250.0 58700.0 0.5 0.3969 0.7913 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I22 mock treatment 518720.0 -18800.0 -0.16 551840.0 51200.0 0.43 0.1946 0.4202 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I23 compound treatment 491400.0 -46100.0 -0.39 503970.0 3380.0 0.03 -0.2569 -0.6537 3186661 PK04_094179 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 I24 compound treatment 364320.0 -173000.0 -1.47 363310.0 -137000.0 -1.16 -1.8651 -0.9932 3186662 PK04_094180 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J01 compound treatment 184040.0 -353000.0 -3.01 243620.0 -257000.0 -2.18 -3.6675 -0.9875 3068611 PK04_094181 CN1C(=O)[C@@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J02 compound treatment 277780.0 -260000.0 -2.21 234560.0 -266000.0 -2.26 -3.1579 -0.9999 3089770 PK04_094182 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J03 compound treatment 350690.0 -187000.0 -1.59 267000.0 -234000.0 -1.98 -2.5247 -0.994 3068612 PK04_094183 OCCCOc1ccc(cc1)C2=N[C@]3(CCS(=O)(=O)c4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J04 compound treatment 305320.0 -232000.0 -1.97 376390.0 -124000.0 -1.05 -2.1415 -0.9567 3001007 PK04_094184 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J05 mock treatment 514740.0 -22700.0 -0.19 447410.0 -53200.0 -0.45 -0.4558 -0.9285 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J06 mock treatment 493800.0 -43700.0 -0.37 373440.0 -127000.0 -1.08 -1.0254 -0.8988 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J07 compound treatment 472640.0 -64800.0 -0.55 416220.0 -84400.0 -0.72 -0.8961 -0.9917 3186665 PK04_094185 CC(C)(C)OC(=O)CC[C@@]12N=C(O[C@H]2c3ccccc3CN(Cc4ccccc4)C1=O)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J08 compound treatment 310880.0 -227000.0 -1.93 316590.0 -184000.0 -1.56 -2.4668 -0.9945 3089771 PK04_094186 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J09 compound treatment 279090.0 -258000.0 -2.2 388760.0 -112000.0 -0.95 -2.2251 -0.9294 3186666 PK04_094187 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4N(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J10 compound treatment 394240.0 -143000.0 -1.22 368110.0 -132000.0 -1.12 -1.6563 -0.9992 3089776 PK04_094188 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccc4OCOc4c3)[C@H]2OC(=O)Nc5ccc6OCOc6c5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J11 compound treatment 515310.0 -22200.0 -0.19 414490.0 -86100.0 -0.73 -0.6498 -0.8614 3068615 PK04_094189 CCCN1C(=O)[C@]2(COC(=N2)c3ccc(OCCCO)cc3)Cc4ccccc14 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J12 compound treatment 320690.0 -217000.0 -1.84 250980.0 -250000.0 -2.12 -2.8013 -0.9976 3001011 PK04_094190 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J13 compound treatment 292230.0 -245000.0 -2.09 320130.0 -180000.0 -1.53 -2.5577 -0.9884 3068616 PK04_094191 OCCCOc1ccc(cc1)C2=N[C@]3(Cc4ccccc4)[C@H](O2)c5ccccc5CN(C(=O)c6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J14 compound treatment 288800.0 -249000.0 -2.12 357250.0 -143000.0 -1.22 -2.3557 -0.9654 3089772 PK04_094192 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H]1OC(=O)Nc5ccc6OCOc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J15 compound treatment 308490.0 -229000.0 -1.95 385330.0 -115000.0 -0.98 -2.0688 -0.9492 3068617 PK04_094193 OCCCOc1ccc(cc1)C2=N[C@@]3(Cc4ccccc4CN(C(=O)c5ccccc5)C3=O)[C@@H](O2)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J16 compound treatment 373500.0 -164000.0 -1.39 381650.0 -119000.0 -1.01 -1.6998 -0.9874 3089773 PK04_094194 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J17 compound treatment 318360.0 -219000.0 -1.86 223400.0 -277000.0 -2.35 -2.9807 -0.9934 3186732 PK04_094195 CN1C(=O)[C@]2(CCS(=O)(=O)c3ccccc3)N=C(O[C@@H]2c4ccccc14)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J18 compound treatment 403110.0 -134000.0 -1.14 298280.0 -202000.0 -1.72 -2.0218 -0.9805 3089774 PK04_094196 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J19 compound treatment 467070.0 -70400.0 -0.6 421820.0 -78800.0 -0.67 -0.896 -0.9985 3186733 PK04_094197 CCCN1C(=O)[C@@]2(Cc3ccccc13)N=C(O[C@H]2c4ccccc4)c5ccc(OCCCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J20 compound treatment 397920.0 -140000.0 -1.19 376090.0 -125000.0 -1.06 -1.5863 -0.9983 3089775 PK04_094198 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccc5OCOc5c4)[C@@H]1OC(=O)Nc6ccc7OCOc7c6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J21 mock treatment 415520.0 -122000.0 -1.04 562030.0 61400.0 0.52 -0.3651 -0.3145 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J22 mock treatment 555310.0 17800.0 0.15 491110.0 -9480.0 -0.08 0.0504 0.2936 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J23 compound treatment 506810.0 -30700.0 -0.26 500700.0 107.0 0.0 -0.1838 -0.7046 3068619 PK04_094199 COC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 J24 compound treatment 266500.0 -271000.0 -2.31 277050.0 -224000.0 -1.9 -2.9709 -0.9953 3089828 PK04_094200 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K01 compound treatment 331010.0 -206000.0 -1.76 404480.0 -96100.0 -0.82 -1.8185 -0.9391 3068620 PK04_094201 COCCCNC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K02 compound treatment 343220.0 -194000.0 -1.65 397540.0 -103000.0 -0.87 -1.7867 -0.9557 3186736 PK04_094202 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K03 compound treatment 310720.0 -227000.0 -1.93 361920.0 -139000.0 -1.18 -2.1958 -0.9719 3186737 PK04_094203 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K04 compound treatment 543080.0 5610.0 0.05 464170.0 -36400.0 -0.31 -0.1847 -0.5909 3068660 PK04_094204 CN(C)C(=O)[C@@]1(CCC(=O)OC(C)(C)C)N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K05 compound treatment 470770.0 -66700.0 -0.57 435630.0 -65000.0 -0.55 -0.7909 -0.9999 3186738 PK04_094205 OCCCOc1ccc(cc1)C2=N[C@@](CCS(=O)(=O)c3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K06 compound treatment 560990.0 23500.0 0.2 473850.0 -26700.0 -0.23 -0.0189 -0.0626 3068661 PK04_094206 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)(CO2)C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K07 mock treatment 497120.0 -40400.0 -0.34 531610.0 31000.0 0.26 -0.0567 -0.1311 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K08 mock treatment 594100.0 56600.0 0.48 593200.0 92600.0 0.79 0.8961 0.9724 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K09 compound treatment 374750.0 -163000.0 -1.38 510420.0 9830.0 0.08 -0.9199 -0.6633 3186739 PK04_094207 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K10 compound treatment 548260.0 10800.0 0.09 571430.0 70800.0 0.6 0.4898 0.8058 3186740 PK04_094208 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K11 compound treatment 382140.0 -155000.0 -1.32 323730.0 -177000.0 -1.5 -1.9953 -0.998 3068664 PK04_094209 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K12 compound treatment 433330.0 -104000.0 -0.89 424870.0 -75700.0 -0.64 -1.0807 -0.9875 3186741 PK04_094210 COCCCNC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K13 compound treatment 492490.0 -45000.0 -0.38 389470.0 -111000.0 -0.94 -0.9371 -0.9212 3068666 PK04_094211 CN(C)C(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K14 compound treatment 437780.0 -99700.0 -0.85 458090.0 -42500.0 -0.36 -0.8546 -0.9274 3186742 PK04_094212 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K15 mock treatment 549640.0 12200.0 0.1 548400.0 47800.0 0.41 0.3599 0.86 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K16 mock treatment 610990.0 73500.0 0.63 587440.0 86800.0 0.74 0.9632 0.9967 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K17 compound treatment 543230.0 5760.0 0.05 385940.0 -115000.0 -0.97 -0.6531 -0.6706 3186743 PK04_094213 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K18 compound treatment 504000.0 -33500.0 -0.28 373120.0 -127000.0 -1.08 -0.966 -0.8639 3068667 PK04_094214 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K19 compound treatment 548480.0 11000.0 0.09 566590.0 66000.0 0.56 0.4621 0.8141 3186744 PK04_094215 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K20 compound treatment 295450.0 -242000.0 -2.06 445930.0 -54700.0 -0.46 -1.7838 -0.8452 3186745 PK04_094216 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K21 compound treatment 372760.0 -165000.0 -1.4 329440.0 -171000.0 -1.45 -2.0174 -0.9998 3068668 PK04_094217 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K22 compound treatment 446950.0 -90500.0 -0.77 511450.0 10900.0 0.09 -0.4794 -0.6181 3186746 PK04_094218 CN(C)C(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K23 mock treatment 479940.0 -57500.0 -0.49 518000.0 17400.0 0.15 -0.2417 -0.4727 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 K24 mock treatment 483330.0 -54100.0 -0.46 541780.0 41200.0 0.35 -0.0787 -0.136 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L01 compound treatment 553010.0 15500.0 0.13 476510.0 -24100.0 -0.2 -0.051 -0.2096 3068669 PK04_094219 CCOC(=O)N1C(N=C(N1C(=O)OCC)c2ccc(OCCCO)cc2)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L02 compound treatment 302450.0 -235000.0 -2.0 287230.0 -213000.0 -1.81 -2.6936 -0.9988 3001020 PK04_094220 CCc1cccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3c4ccccc4)[C@H]2OC(=O)Nc5ccccc5c6ccccc6)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L03 compound treatment 401760.0 -136000.0 -1.15 381980.0 -119000.0 -1.01 -1.5279 -0.9977 3068670 PK04_094221 COCCCNC(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L04 compound treatment 426240.0 -111000.0 -0.95 441620.0 -59000.0 -0.5 -1.0229 -0.9556 3089829 PK04_094222 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L05 compound treatment 408270.0 -129000.0 -1.1 514570.0 14000.0 0.12 -0.6934 -0.6272 3186813 PK04_094223 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L06 compound treatment 296480.0 -241000.0 -2.05 293700.0 -207000.0 -1.76 -2.6907 -0.997 3001022 PK04_094224 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L07 mock treatment 389760.0 -148000.0 -1.26 382790.0 -118000.0 -1.0 -1.5952 -0.9936 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L08 mock treatment 571400.0 33900.0 0.29 561570.0 61000.0 0.52 0.5698 0.962 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L09 compound treatment 571490.0 34000.0 0.29 541400.0 40800.0 0.35 0.4494 0.996 3067926 PK04_094225 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L10 compound treatment 366620.0 -171000.0 -1.45 405380.0 -95200.0 -0.81 -1.5989 -0.9615 3089768 PK04_094226 CCOC(=O)c1ccc(NC(=O)O[C@@H]2[C@@H](CO)O[C@H](OC)[C@@H](OC(=O)Nc3ccccc3)[C@H]2OC(=O)Nc4ccccc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L11 compound treatment 507950.0 -29500.0 -0.25 558170.0 57600.0 0.49 0.1678 0.3055 3186815 PK04_094227 COC(=O)[C@]1(CO)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L12 compound treatment 454720.0 -82800.0 -0.7 469000.0 -31600.0 -0.27 -0.6873 -0.9124 3089830 PK04_094228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(cc2)C(F)(F)F)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L13 compound treatment 546150.0 8680.0 0.07 469890.0 -30700.0 -0.26 -0.132 -0.4875 3067927 PK04_094229 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L14 compound treatment 357150.0 -180000.0 -1.53 333860.0 -167000.0 -1.41 -2.0848 -0.9992 3089831 PK04_094230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2c(C)cccc2OC)[C@H](OC(=O)Nc3ccccc3c4ccccc4)[C@@H]1OC(=O)Nc5ccccc5c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L15 mock treatment 545970.0 8500.0 0.07 532120.0 31500.0 0.27 0.2402 0.8671 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L16 mock treatment 592480.0 55000.0 0.47 426000.0 -74600.0 -0.63 -0.1165 -0.1481 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L17 compound treatment 275520.0 -262000.0 -2.23 226440.0 -274000.0 -2.33 -3.2202 -0.9998 3067928 PK04_094231 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L18 compound treatment 303380.0 -234000.0 -1.99 416320.0 -84300.0 -0.71 -1.9137 -0.9044 3001180 PK04_094232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L19 compound treatment 589370.0 51900.0 0.44 506910.0 6320.0 0.05 0.3501 0.7872 3067929 PK04_094233 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L20 compound treatment 464730.0 -72700.0 -0.62 404700.0 -95900.0 -0.81 -1.0128 -0.9909 3001092 PK04_094234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2c3ccccc3)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L21 compound treatment 518310.0 -19200.0 -0.16 496340.0 -4250.0 -0.04 -0.1408 -0.8432 3067930 PK04_094235 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L22 compound treatment 397600.0 -140000.0 -1.19 314800.0 -186000.0 -1.58 -1.9558 -0.9904 3001093 PK04_094236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Oc3ccccc3)cc2)[C@H](OC(=O)Nc4ccccc4c5ccccc5)[C@@H]1OC(=O)Nc6ccccc6c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L23 mock treatment 556930.0 19500.0 0.17 435140.0 -65500.0 -0.56 -0.2756 -0.4756 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 L24 mock treatment 512010.0 -25500.0 -0.22 501690.0 1100.0 0.01 -0.1466 -0.6761 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M01 compound treatment 243360.0 -294000.0 -2.5 306370.0 -194000.0 -1.65 -2.9342 -0.9794 3067931 PK04_094237 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M02 compound treatment 537760.0 287.0 0.0 547060.0 46500.0 0.39 0.2804 0.7115 3186821 PK04_094238 COCCCNC(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M03 compound treatment 268180.0 -269000.0 -2.29 401350.0 -99200.0 -0.84 -2.2152 -0.9076 3067933 PK04_094239 NC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M04 compound treatment 561710.0 24200.0 0.21 531460.0 30900.0 0.26 0.3309 0.993 3186822 PK04_094240 CC(C)(C)OC(=O)CC[C@@]1(COC(=N1)c2ccc(OCCCO)cc2)C(=O)NCCN3CCOCC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M05 compound treatment 550740.0 13300.0 0.11 494000.0 -6590.0 -0.06 0.0403 0.3196 3067934 PK04_094241 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)(CO2)C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M06 compound treatment 588480.0 51000.0 0.43 543430.0 42800.0 0.36 0.5638 0.9961 3186823 PK04_094242 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M07 compound treatment 218290.0 -319000.0 -2.72 405730.0 -94900.0 -0.8 -2.4891 -0.8789 3186824 PK04_094243 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M08 compound treatment 345060.0 -192000.0 -1.64 373720.0 -127000.0 -1.08 -1.9185 -0.9793 3186825 PK04_094244 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M09 mock treatment 498320.0 -39200.0 -0.33 514810.0 14200.0 0.12 -0.1502 -0.4241 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M10 mock treatment 636640.0 99200.0 0.84 527680.0 27100.0 0.23 0.759 0.8681 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M11 compound treatment 397640.0 -140000.0 -1.19 397920.0 -103000.0 -0.87 -1.457 -0.9883 3067981 PK04_094245 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M12 compound treatment 584320.0 46800.0 0.4 485840.0 -14800.0 -0.13 0.1933 0.4628 3186826 PK04_094246 NC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M13 mock treatment 661810.0 124000.0 1.06 519890.0 19300.0 0.16 0.8637 0.8069 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M14 mock treatment 524520.0 -13000.0 -0.11 583490.0 82900.0 0.7 0.4193 0.5891 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M15 compound treatment 496760.0 -40700.0 -0.35 434880.0 -65700.0 -0.56 -0.6391 -0.9738 3067982 PK04_094247 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M16 compound treatment 369230.0 -168000.0 -1.43 381440.0 -119000.0 -1.01 -1.7268 -0.9855 3186827 PK04_094248 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M17 compound treatment 357640.0 -180000.0 -1.53 442190.0 -58400.0 -0.5 -1.4321 -0.8906 3067983 PK04_094249 CN(C)C(=O)[C@]1(Cc2ccccc2)N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M18 compound treatment 499370.0 -38100.0 -0.32 483370.0 -17200.0 -0.15 -0.3325 -0.9352 3186828 PK04_094250 NC(=O)[C@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@@H]1c3ccccc3CN=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M19 compound treatment 394720.0 -143000.0 -1.21 519080.0 18500.0 0.16 -0.7478 -0.6107 3186829 PK04_094251 CN(C)C(=O)[C@]1(CC=C)N=C(O[C@@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M20 compound treatment 464670.0 -72800.0 -0.62 444870.0 -55700.0 -0.47 -0.7722 -0.9911 3067984 PK04_094252 NC(=O)[C@@]1(Cc2ccccc2)N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M21 compound treatment 331360.0 -206000.0 -1.75 348930.0 -152000.0 -1.29 -2.1496 -0.9884 3186907 PK04_094253 OCCCOc1ccc(cc1)C2=N[C@](CCS(=O)(=O)c3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M22 compound treatment 380680.0 -157000.0 -1.33 475040.0 -25600.0 -0.22 -1.0965 -0.8114 3067985 PK04_094254 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M23 compound treatment 440320.0 -97200.0 -0.83 415290.0 -85300.0 -0.72 -1.0961 -0.9978 3186908 PK04_094255 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 M24 compound treatment 508400.0 -29100.0 -0.25 457820.0 -42800.0 -0.36 -0.4314 -0.9826 3186909 PK04_094256 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N01 compound treatment 539600.0 2130.0 0.02 500330.0 -263.0 0.0 0.0112 0.6153 3067986 PK04_094257 OCCCOc1ccc(cc1)C2=NC(ON2c3ccccc3)C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N02 compound treatment 568340.0 30900.0 0.26 511680.0 11100.0 0.09 0.2522 0.9041 3186910 PK04_094258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N03 compound treatment 471220.0 -66300.0 -0.56 479540.0 -21100.0 -0.18 -0.5248 -0.8877 3067987 PK04_094259 CN(C)C(=O)C1ON(C(=N1)c2ccc(OCCCO)cc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N04 compound treatment 574420.0 36900.0 0.31 536020.0 35400.0 0.3 0.4348 0.9997 3186911 PK04_094260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N05 compound treatment 409350.0 -128000.0 -1.09 405010.0 -95600.0 -0.81 -1.3441 -0.9894 3414052 PK04_094261 COC(=O)[C@@H]1N=C(O[C@@H]1C)c2ccc(OCCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N06 compound treatment 567490.0 30000.0 0.26 547940.0 47300.0 0.4 0.4646 0.9761 3186912 PK04_094262 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N07 compound treatment 573490.0 36000.0 0.31 449290.0 -51300.0 -0.44 -0.0911 -0.1711 3186913 PK04_094263 OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N08 compound treatment 558980.0 21500.0 0.18 338500.0 -162000.0 -1.37 -0.8429 -0.6077 1952953 PK04_094264 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N09 mock treatment 607760.0 70300.0 0.6 560230.0 59600.0 0.51 0.7805 0.9965 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N10 mock treatment 578420.0 40900.0 0.35 473780.0 -26800.0 -0.23 0.0855 0.2055 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N11 compound treatment 496840.0 -40600.0 -0.35 543040.0 42400.0 0.36 0.0102 0.0204 3068027 PK04_094265 CC(=O)OC[C@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N12 compound treatment 528750.0 -8720.0 -0.07 509560.0 8970.0 0.08 0.0013 0.0124 3186914 PK04_094266 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N13 mock treatment 577570.0 40100.0 0.34 544640.0 44000.0 0.37 0.5054 0.999 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N14 mock treatment 551520.0 14000.0 0.12 520480.0 19900.0 0.17 0.2038 0.9857 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N15 compound treatment 613760.0 76300.0 0.65 531210.0 30600.0 0.26 0.6426 0.9192 3068028 PK04_094267 CC(=O)OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N16 compound treatment 577920.0 40400.0 0.34 434530.0 -66100.0 -0.56 -0.1529 -0.2326 3186915 PK04_094268 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N17 compound treatment 609210.0 71700.0 0.61 514620.0 14000.0 0.12 0.5157 0.8294 3068029 PK04_094269 CC(=O)OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N18 compound treatment 540660.0 3190.0 0.03 480090.0 -20500.0 -0.17 -0.1038 -0.5897 1952947 PK04_094270 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@@H](Cc5ccccc5)C/C=C/C[C@H](Cc6ccccc6)C(=O)O[C@@H]14 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N19 compound treatment 564860.0 27400.0 0.23 380320.0 -120000.0 -1.02 -0.5567 -0.5319 3068030 PK04_094271 OC[C@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N20 compound treatment 385990.0 -151000.0 -1.29 352040.0 -149000.0 -1.26 -1.8023 -0.9999 3186916 PK04_094272 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N21 compound treatment 529760.0 -7710.0 -0.07 490820.0 -9770.0 -0.08 -0.105 -0.9933 3068031 PK04_094273 CC(=O)OC[C@@H](C=C)N(C(=O)OC(C)(C)C)S(=O)(=O)c1ccc(Br)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N22 compound treatment 454910.0 -82600.0 -0.7 360160.0 -140000.0 -1.19 -1.339 -0.9683 1952944 PK04_094274 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccccc4)C/C=C/C[C@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N23 compound treatment 440410.0 -97100.0 -0.83 475760.0 -24800.0 -0.21 -0.7328 -0.86 3186917 PK04_094275 CC(=O)OC[C@H](C=C)N(Cc1ccc(cc1)[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 N24 compound treatment 501390.0 -36100.0 -0.31 497530.0 -3060.0 -0.03 -0.2354 -0.7642 3413982 PK04_094276 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O01 compound treatment 138350.0 -399000.0 -3.4 253980.0 -247000.0 -2.09 -3.8802 -0.9729 3068032 PK04_094277 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4N=[N+]=[N-])C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O02 compound treatment 362640.0 -175000.0 -1.49 252000.0 -249000.0 -2.11 -2.5428 -0.9854 3186919 PK04_094278 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O03 compound treatment 409650.0 -128000.0 -1.09 448920.0 -51700.0 -0.44 -1.0789 -0.9202 3068033 PK04_094279 NC(=O)[C@@]1(CC=C)COC(=N1)c2ccc(OCCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O04 compound treatment 503040.0 -34400.0 -0.29 488270.0 -12300.0 -0.1 -0.281 -0.9036 3186920 PK04_094280 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O05 compound treatment 236550.0 -301000.0 -2.56 252480.0 -248000.0 -2.1 -3.2984 -0.9953 3068035 PK04_094281 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3CN=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O06 compound treatment 428430.0 -109000.0 -0.93 399710.0 -101000.0 -0.86 -1.2611 -0.9992 3186921 PK04_094282 CN(C)C(=O)[C@@]1(Cc2ccccc2N=[N+]=[N-])COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O07 compound treatment 264690.0 -273000.0 -2.32 370470.0 -130000.0 -1.1 -2.4214 -0.9423 3186922 PK04_094283 CN(C)C(=O)[C@]1(Cc2ccccc2N=[N+]=[N-])N=C(O[C@@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O08 compound treatment 445550.0 -91900.0 -0.78 446910.0 -53700.0 -0.46 -0.875 -0.9669 3068037 PK04_094284 CN(C)C(=O)[C@@]1(Cc2ccccc2)COC(=N1)c3ccc(OCCCO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O09 compound treatment 338640.0 -199000.0 -1.69 412200.0 -88400.0 -0.75 -1.7263 -0.933 3186923 PK04_094285 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3)([C@@H](O2)c4ccccc4CN=[N+]=[N-])C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O10 compound treatment 386720.0 -151000.0 -1.28 379330.0 -121000.0 -1.03 -1.6342 -0.994 3068038 PK04_094286 OCCCOc1ccc(cc1)C2=N[C@@](Cc3ccccc3N=[N+]=[N-])([C@@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O11 mock treatment 541070.0 3600.0 0.03 445070.0 -55500.0 -0.47 -0.3114 -0.6598 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O12 mock treatment 343270.0 -194000.0 -1.65 255140.0 -245000.0 -2.08 -2.6405 -0.9934 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O13 compound treatment 361070.0 -176000.0 -1.5 454350.0 -46200.0 -0.39 -1.3385 -0.8629 3186924 PK04_094287 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2)c3ccc(OCCCO)cc3)C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O14 compound treatment 288680.0 -249000.0 -2.12 340960.0 -160000.0 -1.35 -2.4541 -0.9767 3186925 PK04_094288 CC(C)(C)OC(=O)CC[C@@]1(N=C(O[C@H]1c2ccccc2CN=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O15 compound treatment 536290.0 -1180.0 -0.01 488380.0 -12200.0 -0.1 -0.0804 -0.7722 3187013 PK04_094289 CC(C)(C)OC(=O)CC[C@]1(N=C(O[C@@H]1c2ccccc2N=[N+]=[N-])c3ccc(OCCCO)cc3)C(=O)N 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O16 compound treatment 372980.0 -164000.0 -1.4 331680.0 -169000.0 -1.43 -2.0027 -0.9999 3068077 PK04_094290 OCCCOc1ccc(cc1)C2=N[C@@](CC=C)([C@@H](O2)c3ccccc3CN=[N+]=[N-])C(=O)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O17 compound treatment 315900.0 -222000.0 -1.88 300760.0 -200000.0 -1.7 -2.5315 -0.9986 3187014 PK04_094291 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)NCC(O)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O18 compound treatment 322080.0 -215000.0 -1.83 360520.0 -140000.0 -1.19 -2.1359 -0.978 3187015 PK04_094292 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O19 compound treatment 483290.0 -54200.0 -0.46 384900.0 -116000.0 -0.98 -1.0199 -0.9406 3068081 PK04_094293 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])(CO2)C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O20 compound treatment 476230.0 -61200.0 -0.52 359050.0 -142000.0 -1.2 -1.2174 -0.9301 3187016 PK04_094294 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3CN=[N+]=[N-])(CO2)C(=O)N4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O21 compound treatment 418140.0 -119000.0 -1.02 324340.0 -176000.0 -1.5 -1.7751 -0.9822 3187017 PK04_094295 COCCCNC(=O)[C@@]1(CCS(=O)(=O)c2ccccc2)N=C(O[C@H]1c3ccccc3)c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O22 compound treatment 389440.0 -148000.0 -1.26 260550.0 -240000.0 -2.04 -2.3303 -0.9733 3068083 PK04_094296 COCCCNC(=O)[C@@]1(Cc2ccccc2CN=[N+]=[N-])N=C(O[C@H]1c3ccccc3N=[N+]=[N-])c4ccc(OCCCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O23 compound treatment 365840.0 -172000.0 -1.46 335520.0 -165000.0 -1.4 -2.0226 -0.9998 3187018 PK04_094297 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3N=[N+]=[N-])([C@H](O2)c4ccccc4)C(=O)N5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 O24 compound treatment 187410.0 -350000.0 -2.98 152640.0 -348000.0 -2.95 -4.1929 -1.0 3068084 PK04_094298 OCCCOc1ccc(cc1)C2=N[C@](CC=C)([C@H](O2)c3ccccc3)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P01 compound treatment 243050.0 -294000.0 -2.5 273440.0 -227000.0 -1.93 -3.1336 -0.9916 3187019 PK04_094299 CC(=O)OC[C@H](C=C)N(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)c2ccc(Br)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P02 compound treatment 257380.0 -280000.0 -2.38 249440.0 -251000.0 -2.13 -3.1914 -0.9984 3413984 PK04_094300 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P03 compound treatment 251850.0 -286000.0 -2.43 317130.0 -183000.0 -1.56 -2.8186 -0.9768 3068086 PK04_094301 COc1ccc(CN([C@H](CO)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P04 compound treatment 280200.0 -257000.0 -2.19 253660.0 -247000.0 -2.09 -3.0288 -0.9998 3413986 PK04_094302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P05 compound treatment 330040.0 -207000.0 -1.76 255610.0 -245000.0 -2.08 -2.7173 -0.9967 3068087 PK04_094303 COc1cc(CN([C@@H](COC(=O)C)C=C)S(=O)(=O)c2ccc(Br)cc2)ccc1OC(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P06 compound treatment 214300.0 -323000.0 -2.75 309560.0 -191000.0 -1.62 -3.0899 -0.9682 1952975 PK04_094304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P07 compound treatment 362110.0 -175000.0 -1.49 331890.0 -169000.0 -1.43 -2.0668 -0.9998 3068088 PK04_094305 OCCCNS(=O)(=O)c1ccc(Br)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P08 compound treatment 261180.0 -276000.0 -2.35 227560.0 -273000.0 -2.32 -3.2998 -1.0 3413993 PK04_094306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4ccccc4)C/C=C/C[C@@H](Cc5ccccc5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P09 compound treatment 262890.0 -275000.0 -2.34 258520.0 -242000.0 -2.05 -3.1038 -0.9979 3068089 PK04_094307 CC[Si](CC)(CC)OC[C@@H](C=C)N(Cc1ccc(OC(=O)C)c(OC)c1)S(=O)(=O)c2ccc(Br)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P10 compound treatment 146970.0 -391000.0 -3.32 167460.0 -333000.0 -2.83 -4.3473 -0.9968 1952969 PK04_094308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5ccccc5)C/C=C/C[C@@H](Cc6ccccc6)C(=O)O[C@@H]14 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P11 mock treatment 347270.0 -190000.0 -1.62 227620.0 -273000.0 -2.32 -2.7815 -0.9846 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P12 mock treatment 331410.0 -206000.0 -1.75 258310.0 -242000.0 -2.06 -2.6928 -0.9969 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P13 compound treatment 282480.0 -255000.0 -2.17 308810.0 -192000.0 -1.63 -2.6843 -0.9899 3068090 PK04_094309 COc1cc(CO)ccc1OC(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P14 compound treatment 296350.0 -241000.0 -2.05 312320.0 -188000.0 -1.6 -2.5798 -0.9923 3068091 PK04_094310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P15 compound treatment 365350.0 -172000.0 -1.46 284800.0 -216000.0 -1.83 -2.3298 -0.9939 3187025 PK04_094311 COc1ccc(CN(C2=CC[C@@]3(C(=O)N)C(=O)C(=C(Cl)C(=O)[C@]3(C2)C#N)Cl)S(=O)(=O)c4ccc(Br)cc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P16 compound treatment 310900.0 -227000.0 -1.93 234950.0 -266000.0 -2.25 -2.9563 -0.997 3187026 PK04_094312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P17 compound treatment 336260.0 -201000.0 -1.71 235200.0 -265000.0 -2.25 -2.8023 -0.9909 3068092 PK04_094313 CC(C)(C)OC(=O)N1[C@H](COC1(C)C)C=C(Br)Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P18 compound treatment 201050.0 -336000.0 -2.86 211230.0 -289000.0 -2.45 -3.7594 -0.9971 3187027 PK04_094314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P19 compound treatment 286400.0 -251000.0 -2.14 221540.0 -279000.0 -2.37 -3.1842 -0.9987 1003211 PK04_094315 CNS(=O)(=O)c1ccc(C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P20 compound treatment 233220.0 -304000.0 -2.59 222720.0 -278000.0 -2.36 -3.497 -0.9989 3187028 PK04_094316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P21 compound treatment 236750.0 -301000.0 -2.56 320250.0 -180000.0 -1.53 -2.8907 -0.9698 3068127 PK04_094317 COc1cc(COC(=O)C)ccc1OC(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P22 compound treatment 207250.0 -330000.0 -2.81 194640.0 -306000.0 -2.6 -3.8216 -0.9992 3187029 PK04_094318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@@H](Cc4ccc5ccccc5c4)C/C=C/C[C@H](Cc6ccc7ccccc7c6)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P23 compound treatment 213770.0 -324000.0 -2.75 301040.0 -200000.0 -1.69 -3.1442 -0.9727 3068129 PK04_094319 OC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2094 P24 compound treatment 276330.0 -261000.0 -2.22 204220.0 -296000.0 -2.51 -3.3486 -0.9981 3413981 PK04_094320 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A01 compound treatment 456160.0 -87200.0 -0.74 454020.0 -74100.0 -0.63 -0.9693 -0.9966 3067957 PK04_095001 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A02 compound treatment 420970.0 -122000.0 -1.04 488990.0 -39200.0 -0.33 -0.9712 -0.8886 3187176 PK04_095002 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A03 compound treatment 441500.0 -102000.0 -0.87 331650.0 -196000.0 -1.67 -1.7915 -0.9536 3067577 PK04_095003 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A04 compound treatment 448080.0 -95300.0 -0.81 385950.0 -142000.0 -1.21 -1.4262 -0.9813 3187436 PK04_095004 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A05 compound treatment 289940.0 -253000.0 -2.16 358770.0 -169000.0 -1.44 -2.5405 -0.9805 3186425 PK04_095005 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6I)c7ccc(cc7)[N+](=O)[O-])cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A06 compound treatment 541610.0 -1770.0 -0.02 425600.0 -103000.0 -0.87 -0.6257 -0.7192 3187069 PK04_095006 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A07 compound treatment 501820.0 -41600.0 -0.35 473490.0 -54700.0 -0.46 -0.5778 -0.991 3187427 PK04_095007 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A08 compound treatment 356890.0 -186000.0 -1.59 223490.0 -305000.0 -2.58 -2.9492 -0.9726 3187515 PK04_095008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc6)c7ccc(cc7)[N+](=O)[O-])cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A09 compound treatment 426330.0 -117000.0 -1.0 480540.0 -47600.0 -0.4 -0.9897 -0.921 3187425 PK04_095009 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A10 compound treatment 411630.0 -132000.0 -1.12 470960.0 -57200.0 -0.49 -1.1356 -0.9298 3068592 PK04_095010 CCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A11 compound treatment 281360.0 -262000.0 -2.23 355620.0 -173000.0 -1.46 -2.611 -0.9792 3187517 PK04_095011 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A12 compound treatment 372830.0 -171000.0 -1.45 344120.0 -184000.0 -1.56 -2.1298 -0.9993 3187344 PK04_095012 COCCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A13 mock treatment 484200.0 -59200.0 -0.5 441050.0 -87100.0 -0.74 -0.8784 -0.9825 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A14 mock treatment 495220.0 -48200.0 -0.41 569630.0 41500.0 0.35 -0.0409 -0.0757 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A15 compound treatment 510520.0 -32900.0 -0.28 498020.0 -30100.0 -0.26 -0.3784 -0.999 3186552 PK04_095013 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A16 compound treatment 423850.0 -120000.0 -1.02 443680.0 -84500.0 -0.72 -1.2257 -0.9853 3187439 PK04_095014 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A17 compound treatment 477700.0 -65700.0 -0.56 497990.0 -30200.0 -0.26 -0.576 -0.9373 3187073 PK04_095015 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A18 compound treatment 495810.0 -47600.0 -0.4 477720.0 -50400.0 -0.43 -0.5886 -0.9996 3187272 PK04_095016 COCCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A19 compound treatment 441700.0 -102000.0 -0.86 374490.0 -154000.0 -1.3 -1.5333 -0.9802 3187508 PK04_095017 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NC3CC3)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A20 compound treatment 300010.0 -243000.0 -2.07 301450.0 -227000.0 -1.92 -2.8238 -0.9993 3186432 PK04_095018 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A21 compound treatment 398480.0 -145000.0 -1.23 460710.0 -67400.0 -0.57 -1.2761 -0.9391 3068646 PK04_095019 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A22 compound treatment 450190.0 -93200.0 -0.79 466310.0 -61800.0 -0.52 -0.9315 -0.9799 3068651 PK04_095020 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A23 compound treatment 462930.0 -80400.0 -0.68 417600.0 -111000.0 -0.94 -1.147 -0.988 3187585 PK04_095021 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 A24 compound treatment 467680.0 -75700.0 -0.64 310400.0 -218000.0 -1.85 -1.7615 -0.9005 3187430 PK04_095022 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B01 compound treatment 192130.0 -351000.0 -2.99 238030.0 -290000.0 -2.46 -3.8531 -0.9954 3187519 PK04_095023 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B02 compound treatment 526770.0 -16600.0 -0.14 553810.0 25700.0 0.22 0.054 0.2082 3186885 PK04_095024 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B03 compound treatment 342650.0 -201000.0 -1.71 522040.0 -6110.0 -0.05 -1.2441 -0.7282 3187435 PK04_095025 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B04 compound treatment 430780.0 -113000.0 -0.96 560900.0 32800.0 0.28 -0.4809 -0.4822 3186491 PK04_095026 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B05 compound treatment 352000.0 -191000.0 -1.63 500220.0 -27900.0 -0.24 -1.3188 -0.8016 3068539 PK04_095027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(F)cc(c4)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B06 compound treatment 485970.0 -57400.0 -0.49 435070.0 -93100.0 -0.79 -0.9036 -0.9733 3186559 PK04_095028 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B07 compound treatment 555280.0 11900.0 0.1 481650.0 -46500.0 -0.39 -0.2073 -0.5091 3068561 PK04_095029 CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B08 compound treatment 254460.0 -289000.0 -2.46 237640.0 -291000.0 -2.46 -3.4805 -1.0 3068322 PK04_095030 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B09 compound treatment 515310.0 -28100.0 -0.24 505950.0 -22200.0 -0.19 -0.302 -0.9931 3187432 PK04_095031 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B10 compound treatment 417950.0 -125000.0 -1.07 325310.0 -203000.0 -1.72 -1.9712 -0.9736 3068145 PK04_095032 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(F)(F)F)c5ccccc5C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B11 compound treatment 534500.0 -8880.0 -0.08 507000.0 -21100.0 -0.18 -0.1803 -0.9261 3187265 PK04_095033 CC(C)N1[C@H]([C@H](C(=O)NCCCN(C)C)c2ccccc2C1=O)c3ccc(CO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B12 compound treatment 314080.0 -229000.0 -1.95 498180.0 -30000.0 -0.25 -1.5591 -0.7926 3186629 PK04_095034 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B13 mock treatment 560270.0 16900.0 0.14 586120.0 58000.0 0.49 0.4493 0.8771 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B14 mock treatment 555430.0 12100.0 0.1 547910.0 19800.0 0.17 0.191 0.9722 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B15 compound treatment 473870.0 -69500.0 -0.59 524320.0 -3830.0 -0.03 -0.4411 -0.7448 3187269 PK04_095035 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3CCCCC3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B16 compound treatment 498080.0 -45300.0 -0.39 510410.0 -17700.0 -0.15 -0.3789 -0.9159 3186887 PK04_095036 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B17 compound treatment 524700.0 -18700.0 -0.16 528000.0 -149.0 0.0 -0.1132 -0.7127 3068417 PK04_095037 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B18 compound treatment 507360.0 -36000.0 -0.31 459520.0 -68600.0 -0.58 -0.6283 -0.9551 3067610 PK04_095038 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(C7CC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B19 compound treatment 505770.0 -37600.0 -0.32 462760.0 -65400.0 -0.55 -0.6184 -0.9658 3068639 PK04_095039 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B20 compound treatment 487760.0 -55600.0 -0.47 507430.0 -20700.0 -0.18 -0.4588 -0.9091 3068006 PK04_095040 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B21 compound treatment 567040.0 23700.0 0.2 466780.0 -61400.0 -0.52 -0.2258 -0.4045 3068601 PK04_095041 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCc4ccccc4)c5ccccc5C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B22 compound treatment 500000.0 -43400.0 -0.37 516200.0 -11900.0 -0.1 -0.3326 -0.8691 3068203 PK04_095042 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5Cl)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B23 compound treatment 533940.0 -9440.0 -0.08 517070.0 -11100.0 -0.09 -0.1232 -0.9969 3187355 PK04_095043 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCC(F)(F)F)c4ccccc4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 B24 compound treatment 505360.0 -38000.0 -0.32 543780.0 15600.0 0.13 -0.1349 -0.386 3068156 PK04_095044 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C01 compound treatment 480120.0 -63300.0 -0.54 501210.0 -26900.0 -0.23 -0.5421 -0.9272 3187590 PK04_095045 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C02 compound treatment 487050.0 -56300.0 -0.48 488510.0 -39600.0 -0.34 -0.5766 -0.985 3187180 PK04_095046 CC(C)NC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C03 compound treatment 335950.0 -207000.0 -1.76 283750.0 -244000.0 -2.07 -2.7137 -0.9968 3186493 PK04_095047 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C04 compound treatment 12390.0 -531000.0 -4.52 10830.0 -517000.0 -4.39 -6.2972 -0.9999 3186427 PK04_095048 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C05 compound treatment 358250.0 -185000.0 -1.57 444030.0 -84100.0 -0.71 -1.6182 -0.9359 3187172 PK04_095049 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C06 compound treatment 462430.0 -80900.0 -0.69 466370.0 -61800.0 -0.52 -0.8575 -0.9909 3187080 PK04_095050 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C07 compound treatment 477000.0 -66400.0 -0.56 452430.0 -75700.0 -0.64 -0.8535 -0.9979 3186988 PK04_095051 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C08 compound treatment 202120.0 -341000.0 -2.9 233940.0 -294000.0 -2.5 -3.8176 -0.9972 3068011 PK04_095052 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C09 compound treatment 443310.0 -100000.0 -0.85 474640.0 -53500.0 -0.45 -0.9229 -0.9566 3068498 PK04_095053 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C10 compound treatment 131620.0 -412000.0 -3.5 120640.0 -408000.0 -3.46 -4.9213 -1.0 3186550 PK04_095054 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C11 mock treatment 365860.0 -178000.0 -1.51 475400.0 -52700.0 -0.45 -1.3843 -0.8789 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C12 mock treatment 499230.0 -44100.0 -0.38 499000.0 -29100.0 -0.25 -0.4404 -0.9794 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C13 compound treatment 495520.0 -47900.0 -0.41 461730.0 -66400.0 -0.56 -0.6863 -0.9873 3187361 PK04_095055 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C14 compound treatment 423050.0 -120000.0 -1.02 474720.0 -53400.0 -0.45 -1.0443 -0.9328 3068504 PK04_095056 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C15 mock treatment 494500.0 -48900.0 -0.42 480000.0 -48100.0 -0.41 -0.5828 -1.0 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C16 mock treatment 530470.0 -12900.0 -0.11 470680.0 -57500.0 -0.49 -0.4223 -0.8452 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C17 compound treatment 511940.0 -31400.0 -0.27 449480.0 -78700.0 -0.67 -0.661 -0.9194 3067969 PK04_095057 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCCN(C)C)c3ccc(cc3)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C18 compound treatment 350960.0 -192000.0 -1.64 413470.0 -115000.0 -0.97 -1.8454 -0.9691 3187359 PK04_095058 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(Cc3ccc(OC(F)(F)F)cc3)C(=O)c4ccccc42)c5ccc(CO)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C19 compound treatment 482150.0 -61200.0 -0.52 501230.0 -26900.0 -0.23 -0.5298 -0.9315 3187087 PK04_095059 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C20 compound treatment 451940.0 -91400.0 -0.78 484220.0 -43900.0 -0.37 -0.8135 -0.9432 3187443 PK04_095060 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C21 compound treatment 374200.0 -169000.0 -1.44 387310.0 -141000.0 -1.19 -1.8625 -0.9957 3067571 PK04_095061 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C22 compound treatment 477380.0 -66000.0 -0.56 441830.0 -86300.0 -0.73 -0.9148 -0.9914 3187181 PK04_095062 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C23 compound treatment 434170.0 -109000.0 -0.93 343100.0 -185000.0 -1.57 -1.7669 -0.9687 3187509 PK04_095063 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)c4ccc(cc4)[N+](=O)[O-])cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 C24 compound treatment 452730.0 -90600.0 -0.77 416110.0 -112000.0 -0.95 -1.2173 -0.9946 3068474 PK04_095064 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D01 compound treatment 416190.0 -127000.0 -1.08 411680.0 -116000.0 -0.99 -1.4637 -0.999 3068587 PK04_095065 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(CC3(CC4CC5CC(C4)C3)C5)C(=O)c6ccccc26)c7ccc(CO)cc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D02 compound treatment 236190.0 -307000.0 -2.61 247040.0 -281000.0 -2.38 -3.534 -0.999 3068318 PK04_095066 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D03 compound treatment 550470.0 7090.0 0.06 515540.0 -12600.0 -0.11 -0.033 -0.2684 3187363 PK04_095067 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D04 compound treatment 580970.0 37600.0 0.32 563940.0 35800.0 0.3 0.4408 0.9997 3186486 PK04_095068 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CCN7CCOCC7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D05 compound treatment 522800.0 -20600.0 -0.18 523060.0 -5090.0 -0.04 -0.1543 -0.8558 3187179 PK04_095069 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(=O)c3ccccc23)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D06 compound treatment 266660.0 -277000.0 -2.35 272870.0 -255000.0 -2.17 -3.1958 -0.9991 3187522 PK04_095070 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D07 compound treatment 563370.0 20000.0 0.17 513820.0 -14300.0 -0.12 0.0343 0.1642 3068515 PK04_095071 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D08 compound treatment 467000.0 -76400.0 -0.65 389140.0 -139000.0 -1.18 -1.2932 -0.9606 3186872 PK04_095072 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D09 compound treatment 450680.0 -92700.0 -0.79 419950.0 -108000.0 -0.92 -1.2066 -0.9971 3068609 PK04_095073 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D10 compound treatment 251780.0 -292000.0 -2.48 268280.0 -260000.0 -2.2 -3.3129 -0.9983 3186795 PK04_095074 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D11 mock treatment 560480.0 17100.0 0.15 547480.0 19300.0 0.16 0.2188 0.9982 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D12 mock treatment 560240.0 16900.0 0.14 578680.0 50500.0 0.43 0.4045 0.895 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D13 compound treatment 518400.0 -25000.0 -0.21 445220.0 -82900.0 -0.7 -0.6477 -0.8814 3067964 PK04_095075 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D14 compound treatment 577280.0 33900.0 0.29 494430.0 -33700.0 -0.29 0.0017 0.0042 3068230 PK04_095076 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D15 mock treatment 574500.0 31100.0 0.26 495040.0 -33100.0 -0.28 -0.0114 -0.0295 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D16 mock treatment 552360.0 8980.0 0.08 541570.0 13400.0 0.11 0.1345 0.9812 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D17 compound treatment 524060.0 -19300.0 -0.16 558500.0 30400.0 0.26 0.0659 0.2156 3068595 PK04_095077 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCc3ccccc3)c4ccccc4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D18 compound treatment 406910.0 -136000.0 -1.16 476570.0 -51600.0 -0.44 -1.1303 -0.911 3186982 PK04_095078 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D19 compound treatment 525720.0 -17700.0 -0.15 461440.0 -66700.0 -0.57 -0.5063 -0.8649 3187440 PK04_095079 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D20 compound treatment 533020.0 -10400.0 -0.09 436810.0 -91300.0 -0.77 -0.6102 -0.7825 3068415 PK04_095080 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D21 compound treatment 482340.0 -61000.0 -0.52 513480.0 -14700.0 -0.12 -0.4552 -0.8524 3068596 PK04_095081 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCC(F)(F)F)c3ccccc3C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D22 compound treatment 232760.0 -311000.0 -2.64 244390.0 -284000.0 -2.41 -3.5706 -0.9989 3186713 PK04_095082 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D23 compound treatment 470210.0 -73200.0 -0.62 540870.0 12700.0 0.11 -0.3638 -0.5759 3187357 PK04_095083 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 D24 compound treatment 208400.0 -335000.0 -2.85 216800.0 -311000.0 -2.64 -3.8826 -0.9993 3068270 PK04_095084 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCCN6CCOCC6)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E01 mock treatment 558130.0 14800.0 0.13 521520.0 -6630.0 -0.06 0.049 0.3562 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E02 mock treatment 540800.0 -2580.0 -0.02 571520.0 43400.0 0.37 0.2446 0.6638 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E03 compound treatment 456820.0 -86600.0 -0.74 490240.0 -37900.0 -0.32 -0.7481 -0.931 3068636 PK04_095085 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E04 compound treatment 556690.0 13300.0 0.11 484530.0 -43600.0 -0.37 -0.1815 -0.4692 3186556 PK04_095086 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E05 compound treatment 526450.0 -16900.0 -0.14 481080.0 -47100.0 -0.4 -0.3841 -0.9051 3187587 PK04_095087 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E06 compound treatment 265440.0 -278000.0 -2.36 335150.0 -193000.0 -1.64 -2.8296 -0.9839 3186428 PK04_095088 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E07 compound treatment 360870.0 -183000.0 -1.55 497080.0 -31100.0 -0.26 -1.2842 -0.8155 3187266 PK04_095089 CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E08 compound treatment 540350.0 -3030.0 -0.03 573480.0 45300.0 0.38 0.2537 0.6583 3187351 PK04_095090 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E09 mock treatment 580180.0 36800.0 0.31 527400.0 -749.0 -0.01 0.2169 0.6926 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E10 mock treatment 593320.0 49900.0 0.42 502360.0 -25800.0 -0.22 0.1458 0.305 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E11 compound treatment 575090.0 31700.0 0.27 584580.0 56400.0 0.48 0.5293 0.9632 3068004 PK04_095091 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E12 compound treatment 531640.0 -11700.0 -0.1 426030.0 -102000.0 -0.87 -0.6831 -0.7834 3186500 PK04_095092 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E13 compound treatment 575320.0 31900.0 0.27 468050.0 -60100.0 -0.51 -0.1683 -0.2914 3187346 PK04_095093 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCN3CCOCC3)c4ccccc4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E14 compound treatment 573080.0 29700.0 0.25 525640.0 -2510.0 -0.02 0.1636 0.6453 3187262 PK04_095094 CC(C)N1[C@H]([C@H](C(=O)NCCN2CCOCC2)c3ccccc3C1=O)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E15 compound treatment 439480.0 -104000.0 -0.88 395780.0 -132000.0 -1.12 -1.419 -0.993 3067574 PK04_095095 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E16 compound treatment 568200.0 24800.0 0.21 554950.0 26800.0 0.23 0.3101 0.9993 3187350 PK04_095096 COCCCNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E17 mock treatment 546440.0 3060.0 0.03 497460.0 -30700.0 -0.26 -0.1656 -0.6332 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E18 mock treatment 583560.0 40200.0 0.34 520530.0 -7620.0 -0.06 0.196 0.5634 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E19 compound treatment 515840.0 -27500.0 -0.23 409280.0 -119000.0 -1.01 -0.8786 -0.8488 3068657 PK04_095097 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E20 compound treatment 441950.0 -101000.0 -0.86 516610.0 -11500.0 -0.1 -0.6793 -0.7823 3068140 PK04_095098 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E21 compound treatment 532560.0 -10800.0 -0.09 471420.0 -56700.0 -0.48 -0.4053 -0.8273 3186562 PK04_095099 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E22 compound treatment 557960.0 14600.0 0.12 565480.0 37300.0 0.32 0.3116 0.9163 3187591 PK04_095100 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E23 compound treatment 546900.0 3520.0 0.03 507790.0 -20400.0 -0.17 -0.1009 -0.5758 3187263 PK04_095101 CC(C)N1[C@H]([C@H](C(=O)NCc2ccccc2)c3ccccc3C1=O)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 E24 compound treatment 431360.0 -112000.0 -0.95 493340.0 -34800.0 -0.3 -0.8826 -0.8847 3068517 PK04_095102 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F01 mock treatment 562370.0 19000.0 0.16 570620.0 42500.0 0.36 0.369 0.9346 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F02 mock treatment 528500.0 -14900.0 -0.13 578190.0 50000.0 0.42 0.2107 0.4756 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F03 compound treatment 454850.0 -88500.0 -0.75 438040.0 -90100.0 -0.76 -1.073 -1.0 3187079 PK04_095103 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F04 compound treatment 432610.0 -111000.0 -0.94 408870.0 -119000.0 -1.01 -1.3818 -0.9994 3068331 PK04_095104 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F05 compound treatment 348180.0 -195000.0 -1.66 408730.0 -119000.0 -1.01 -1.8905 -0.9719 3068563 PK04_095105 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F06 compound treatment 391050.0 -152000.0 -1.3 430510.0 -97600.0 -0.83 -1.502 -0.9766 3186879 PK04_095106 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCCN6CCOCC6)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F07 compound treatment 265620.0 -278000.0 -2.36 265140.0 -263000.0 -2.23 -3.2484 -0.9996 3187523 PK04_095107 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F08 compound treatment 545620.0 2240.0 0.02 528870.0 721.0 0.01 0.0178 0.8892 3186563 PK04_095108 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F09 mock treatment 525340.0 -18000.0 -0.15 567390.0 39200.0 0.33 0.1269 0.3462 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F10 mock treatment 564640.0 21300.0 0.18 561170.0 33000.0 0.28 0.326 0.9776 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F11 compound treatment 537870.0 -5510.0 -0.05 446670.0 -81500.0 -0.69 -0.5218 -0.7533 3187257 PK04_095109 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F12 compound treatment 279270.0 -264000.0 -2.25 267680.0 -260000.0 -2.21 -3.1511 -1.0 3068241 PK04_095110 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F13 compound treatment 552060.0 8680.0 0.07 431480.0 -96700.0 -0.82 -0.5276 -0.6408 3068554 PK04_095111 COCCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F14 compound treatment 451610.0 -91800.0 -0.78 549950.0 21800.0 0.18 -0.4213 -0.5251 3068362 PK04_095112 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3)Sc4ccc(C)cc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F15 compound treatment 542650.0 -727.0 -0.01 359330.0 -169000.0 -1.43 -1.017 -0.7102 3186423 PK04_095113 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F16 compound treatment 538120.0 -5260.0 -0.04 495570.0 -32600.0 -0.28 -0.227 -0.811 3068012 PK04_095114 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)O)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F17 mock treatment 573280.0 29900.0 0.25 554160.0 26000.0 0.22 0.3359 0.9975 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F18 mock treatment 501050.0 -42300.0 -0.36 516370.0 -11800.0 -0.1 -0.3253 -0.8704 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F19 compound treatment 362890.0 -180000.0 -1.54 385680.0 -142000.0 -1.21 -1.9403 -0.993 3067568 PK04_095115 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F20 compound treatment 275540.0 -268000.0 -2.28 263160.0 -265000.0 -2.25 -3.2006 -1.0 3068266 PK04_095116 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F21 compound treatment 420510.0 -123000.0 -1.05 409440.0 -119000.0 -1.01 -1.4511 -0.9998 3186419 PK04_095117 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F22 compound treatment 257440.0 -286000.0 -2.43 240010.0 -288000.0 -2.44 -3.4484 -1.0 3187524 PK04_095118 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F23 compound treatment 558080.0 14700.0 0.13 519800.0 -8350.0 -0.07 0.0384 0.267 3068017 PK04_095119 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)O)c4ccccc4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 F24 compound treatment 414370.0 -129000.0 -1.1 370810.0 -157000.0 -1.33 -1.7198 -0.9953 3186554 PK04_095120 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G01 compound treatment 289660.0 -254000.0 -2.16 352320.0 -176000.0 -1.49 -2.5809 -0.9837 3186418 PK04_095121 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G02 compound treatment 422190.0 -121000.0 -1.03 539960.0 11800.0 0.1 -0.6582 -0.6354 3067966 PK04_095122 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCCN3CCOCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G03 mock treatment 551800.0 8420.0 0.07 428210.0 -99900.0 -0.85 -0.5488 -0.645 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G04 mock treatment 563740.0 20400.0 0.17 526440.0 -1710.0 -0.01 0.1122 0.6457 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G05 compound treatment 463150.0 -80200.0 -0.68 432960.0 -95200.0 -0.81 -1.0536 -0.9965 3068153 PK04_095123 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NC6CC6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G06 compound treatment 544660.0 1280.0 0.01 566730.0 38600.0 0.33 0.2391 0.7303 3187356 PK04_095124 COCCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G07 compound treatment 470250.0 -73100.0 -0.62 352340.0 -176000.0 -1.49 -1.4944 -0.9248 3187173 PK04_095125 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G08 compound treatment 579760.0 36400.0 0.31 494750.0 -33400.0 -0.28 0.0185 0.0442 3068514 PK04_095126 CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G09 compound treatment 511040.0 -32300.0 -0.28 603490.0 75300.0 0.64 0.2574 0.3699 3187442 PK04_095127 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G10 compound treatment 552800.0 9420.0 0.08 573000.0 44900.0 0.38 0.3257 0.8377 3068420 PK04_095128 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G11 compound treatment 548640.0 5260.0 0.04 579420.0 51300.0 0.43 0.3392 0.7758 3187434 PK04_095129 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G12 compound treatment 226780.0 -317000.0 -2.69 290530.0 -238000.0 -2.02 -3.3298 -0.9898 3186416 PK04_095130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G13 compound treatment 471130.0 -72200.0 -0.61 526100.0 -2050.0 -0.02 -0.4469 -0.7268 3068507 PK04_095131 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G14 compound treatment 546520.0 3140.0 0.03 509710.0 -18400.0 -0.16 -0.0917 -0.5778 3187162 PK04_095132 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G15 compound treatment 602580.0 59200.0 0.5 567710.0 39600.0 0.34 0.5934 0.9805 3068602 PK04_095133 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G16 compound treatment 533080.0 -10300.0 -0.09 485330.0 -42800.0 -0.36 -0.3188 -0.8532 3187426 PK04_095134 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G17 compound treatment 473800.0 -69600.0 -0.59 398730.0 -129000.0 -1.1 -1.1948 -0.958 3067567 PK04_095135 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G18 compound treatment 258800.0 -285000.0 -2.42 266340.0 -262000.0 -2.22 -3.2823 -0.9991 3187525 PK04_095136 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G19 mock treatment 527770.0 -15600.0 -0.13 474560.0 -53600.0 -0.45 -0.4153 -0.877 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G20 mock treatment 549700.0 6320.0 0.05 607600.0 79500.0 0.67 0.5146 0.7611 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G21 compound treatment 558920.0 15500.0 0.13 528000.0 -149.0 0.0 0.0926 0.7003 3187167 PK04_095137 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G22 compound treatment 528120.0 -15300.0 -0.13 567200.0 39100.0 0.33 0.1425 0.4004 3187174 PK04_095138 COc1ccccc1CN2[C@H]([C@H](C(=O)NC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G23 compound treatment 542660.0 -717.0 -0.01 479540.0 -48600.0 -0.41 -0.2959 -0.7175 3068478 PK04_095139 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 G24 compound treatment 499070.0 -44300.0 -0.38 440530.0 -87600.0 -0.74 -0.7921 -0.9505 3068471 PK04_095140 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H01 compound treatment 389200.0 -154000.0 -1.31 417550.0 -111000.0 -0.94 -1.5909 -0.9865 3068149 PK04_095141 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H02 compound treatment 274120.0 -269000.0 -2.29 246280.0 -282000.0 -2.39 -3.3104 -0.9998 3068236 PK04_095142 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H03 mock treatment 551170.0 7790.0 0.07 403040.0 -125000.0 -1.06 -0.7035 -0.6616 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H04 mock treatment 561880.0 18500.0 0.16 544920.0 16800.0 0.14 0.2119 0.9987 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H05 compound treatment 289990.0 -253000.0 -2.16 562110.0 34000.0 0.29 -1.3206 -0.6072 3187083 PK04_095143 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H06 compound treatment 249870.0 -294000.0 -2.5 266740.0 -261000.0 -2.22 -3.3336 -0.9982 3068265 PK04_095144 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H07 compound treatment 542170.0 -1210.0 -0.01 546150.0 18000.0 0.15 0.1007 0.6581 3068458 PK04_095145 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H08 compound treatment 457080.0 -86300.0 -0.73 555070.0 26900.0 0.23 -0.3576 -0.4652 3068401 PK04_095146 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H09 compound treatment 590480.0 47100.0 0.4 596250.0 68100.0 0.58 0.6918 0.984 3187071 PK04_095147 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H10 compound treatment 492160.0 -51200.0 -0.44 411120.0 -117000.0 -0.99 -1.0101 -0.9317 3068139 PK04_095148 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H11 compound treatment 637690.0 94300.0 0.8 580320.0 52200.0 0.44 0.8803 0.9607 3187589 PK04_095149 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H12 compound treatment 564280.0 20900.0 0.18 549440.0 21300.0 0.18 0.2535 1.0 3186627 PK04_095150 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H13 compound treatment 308550.0 -235000.0 -2.0 536890.0 8740.0 0.07 -1.3602 -0.6804 3187261 PK04_095151 CC(C)N1[C@H]([C@H](C(=O)NC2CC2)c3ccccc3C1=O)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H14 compound treatment 532020.0 -11400.0 -0.1 571620.0 43500.0 0.37 0.1924 0.5048 3186980 PK04_095152 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H15 compound treatment 411740.0 -132000.0 -1.12 536750.0 8600.0 0.07 -0.7403 -0.6596 3187166 PK04_095153 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H16 compound treatment 616380.0 73000.0 0.62 424490.0 -104000.0 -0.88 -0.1826 -0.1696 3186978 PK04_095154 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H17 compound treatment 551140.0 7760.0 0.07 516130.0 -12000.0 -0.1 -0.0254 -0.209 3187349 PK04_095155 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NCCCN(C)C)c3ccccc3C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H18 compound treatment 617450.0 74100.0 0.63 556400.0 28300.0 0.24 0.6151 0.9123 3068412 PK04_095156 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H19 mock treatment 560860.0 17500.0 0.15 589760.0 61600.0 0.52 0.4747 0.8737 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H20 mock treatment 518560.0 -24800.0 -0.21 574260.0 46100.0 0.39 0.1273 0.2864 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H21 compound treatment 538630.0 -4750.0 -0.04 482680.0 -45500.0 -0.39 -0.3013 -0.7769 3187512 PK04_095157 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H22 compound treatment 267700.0 -276000.0 -2.35 259780.0 -268000.0 -2.28 -3.2681 -0.9999 3186806 PK04_095158 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H23 compound treatment 509530.0 -33800.0 -0.29 499120.0 -29000.0 -0.25 -0.3777 -0.997 3068599 PK04_095159 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NC4CC4)c5ccccc5C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 H24 compound treatment 513440.0 -29900.0 -0.25 521330.0 -6820.0 -0.06 -0.221 -0.8462 3187586 PK04_095160 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I01 compound treatment 519520.0 -23900.0 -0.2 474340.0 -53800.0 -0.46 -0.4663 -0.9334 3187165 PK04_095161 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccc(OC(F)(F)F)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I02 compound treatment 470260.0 -73100.0 -0.62 517560.0 -10600.0 -0.09 -0.5034 -0.8009 3068418 PK04_095162 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I03 compound treatment 543270.0 -107.0 0.0 450340.0 -77800.0 -0.66 -0.4674 -0.7081 3187178 PK04_095163 Cc1ccc(nc1)N2[C@H]([C@H](C(=O)NCCN3CCOCC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I04 compound treatment 554810.0 11400.0 0.1 544060.0 15900.0 0.13 0.1642 0.9871 3068019 PK04_095164 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I05 mock treatment 558270.0 14900.0 0.13 502960.0 -25200.0 -0.21 -0.0615 -0.2476 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I06 mock treatment 516060.0 -27300.0 -0.23 522030.0 -6120.0 -0.05 -0.201 -0.8442 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I07 compound treatment 502740.0 -40600.0 -0.35 490430.0 -37700.0 -0.32 -0.4707 -0.9993 3068542 PK04_095165 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C3Cc4ccccc4C3)C(=O)c5ccccc25)c6ccc(CO)cc6)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I08 compound treatment 500210.0 -43200.0 -0.37 577790.0 49600.0 0.42 0.0381 0.0682 3187345 PK04_095166 CC(C)CNC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I09 compound treatment 201360.0 -342000.0 -2.91 212980.0 -315000.0 -2.67 -3.9479 -0.9991 3067971 PK04_095167 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I10 compound treatment 602430.0 59100.0 0.5 570660.0 42500.0 0.36 0.6102 0.9868 3068641 PK04_095168 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I11 compound treatment 630130.0 86800.0 0.74 583080.0 54900.0 0.47 0.8514 0.9754 3187358 PK04_095169 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I12 compound treatment 591150.0 47800.0 0.41 544710.0 16600.0 0.14 0.3867 0.8993 3068653 PK04_095170 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I13 compound treatment 554630.0 11300.0 0.1 489630.0 -38500.0 -0.33 -0.1633 -0.4798 3067962 PK04_095171 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I14 compound treatment 607450.0 64100.0 0.55 432230.0 -95900.0 -0.81 -0.1899 -0.1939 3068606 PK04_095172 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I15 compound treatment 581040.0 37700.0 0.32 578620.0 50500.0 0.43 0.5293 0.9898 3068476 PK04_095173 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I16 compound treatment 396480.0 -147000.0 -1.25 409480.0 -119000.0 -1.01 -1.5955 -0.9942 3186417 PK04_095174 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NC4CC4)c5ccc(cc5)[N+](=O)[O-])c(I)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I17 compound treatment 569200.0 25800.0 0.22 432800.0 -95300.0 -0.81 -0.4166 -0.497 3187268 PK04_095175 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I18 compound treatment 581080.0 37700.0 0.32 575360.0 47200.0 0.4 0.51 0.9939 3187264 PK04_095176 CC(C)N1[C@H]([C@H](C(=O)NCC(F)(F)F)c2ccccc2C1=O)c3ccc(CO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I19 compound treatment 534750.0 -8630.0 -0.07 567090.0 38900.0 0.33 0.1817 0.5369 3186499 PK04_095177 COCCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3OC)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I20 compound treatment 518050.0 -25300.0 -0.22 478670.0 -49500.0 -0.42 -0.4491 -0.952 3068422 PK04_095178 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I21 mock treatment 538880.0 -4500.0 -0.04 562130.0 34000.0 0.29 0.1768 0.6079 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I22 mock treatment 517280.0 -26100.0 -0.22 538940.0 10800.0 0.09 -0.0923 -0.3842 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I23 compound treatment 546410.0 3030.0 0.03 491210.0 -36900.0 -0.31 -0.2033 -0.6467 3068550 PK04_095179 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(C(C)C)C(=O)c3ccccc23)c4ccc(CO)cc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 I24 compound treatment 509000.0 -34400.0 -0.29 502400.0 -25700.0 -0.22 -0.3612 -0.9897 3187258 PK04_095180 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4Cc5ccccc5C4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J01 compound treatment 473150.0 -70200.0 -0.6 469250.0 -58900.0 -0.5 -0.7757 -0.996 3187273 PK04_095181 CC(C)CNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J02 compound treatment 510120.0 -33300.0 -0.28 484970.0 -43200.0 -0.37 -0.4591 -0.9919 3186630 PK04_095182 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J03 compound treatment 501820.0 -41600.0 -0.35 496890.0 -31300.0 -0.27 -0.4375 -0.99 3187353 PK04_095183 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(=O)c3ccccc32)c4ccc(C)cn4)c5ccc(CO)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J04 compound treatment 553510.0 10100.0 0.09 574020.0 45900.0 0.39 0.3361 0.8433 3187588 PK04_095184 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)O)c3ccccc3C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J05 mock treatment 634890.0 91500.0 0.78 443810.0 -84300.0 -0.72 0.0446 0.0422 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J06 mock treatment 584560.0 41200.0 0.35 475860.0 -52300.0 -0.44 -0.0659 -0.1166 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J07 compound treatment 233600.0 -310000.0 -2.64 333600.0 -195000.0 -1.65 -3.0304 -0.9746 3186420 PK04_095185 OCc1ccc([C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c4ccc(cc4)[N+](=O)[O-])c(I)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J08 compound treatment 283320.0 -260000.0 -2.21 236030.0 -292000.0 -2.48 -3.3166 -0.9984 3186722 PK04_095186 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J09 compound treatment 347290.0 -196000.0 -1.67 295380.0 -233000.0 -1.97 -2.5758 -0.9965 3186426 PK04_095187 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J10 compound treatment 558440.0 15100.0 0.13 509980.0 -18200.0 -0.15 -0.0184 -0.0916 3186639 PK04_095188 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J11 compound treatment 568720.0 25300.0 0.22 571690.0 43500.0 0.37 0.4136 0.9672 3187270 PK04_095189 CC(C)NC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J12 compound treatment 574990.0 31600.0 0.27 544850.0 16700.0 0.14 0.2904 0.9552 3067980 PK04_095190 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J13 compound treatment 331550.0 -212000.0 -1.8 284800.0 -243000.0 -2.06 -2.7339 -0.9977 3186421 PK04_095191 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J14 compound treatment 544700.0 1320.0 0.01 540910.0 12800.0 0.11 0.0845 0.7765 3068150 PK04_095192 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J15 compound treatment 645550.0 102000.0 0.87 565310.0 37200.0 0.32 0.8375 0.9058 3068598 PK04_095193 CCCNC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J16 compound treatment 269340.0 -274000.0 -2.33 242080.0 -286000.0 -2.43 -3.3644 -0.9998 3068324 PK04_095194 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J17 compound treatment 206240.0 -337000.0 -2.87 238920.0 -289000.0 -2.45 -3.7629 -0.997 3067973 PK04_095195 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J18 compound treatment 489760.0 -53600.0 -0.46 535200.0 7050.0 0.06 -0.2802 -0.6092 3068414 PK04_095196 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J19 compound treatment 562670.0 19300.0 0.16 573450.0 45300.0 0.38 0.3878 0.928 3187085 PK04_095197 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J20 compound treatment 533990.0 -9390.0 -0.08 558500.0 30400.0 0.26 0.1256 0.4659 3186884 PK04_095198 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J21 mock treatment 583890.0 40500.0 0.34 569060.0 40900.0 0.35 0.4891 1.0 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J22 mock treatment 551290.0 7910.0 0.07 549780.0 21600.0 0.18 0.1774 0.9074 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J23 compound treatment 509570.0 -33800.0 -0.29 502620.0 -25500.0 -0.22 -0.3565 -0.9902 3187082 PK04_095199 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 J24 compound treatment 490620.0 -52800.0 -0.45 522080.0 -6070.0 -0.05 -0.3538 -0.7831 3068227 PK04_095200 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K01 compound treatment 298360.0 -245000.0 -2.08 182160.0 -346000.0 -2.93 -3.5492 -0.9859 3187514 PK04_095201 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NC6CC6)c7ccc(cc7)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K02 compound treatment 565950.0 22600.0 0.19 513510.0 -14600.0 -0.12 0.048 0.2098 3187168 PK04_095202 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccc(OC(F)(F)F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K03 compound treatment 532120.0 -11300.0 -0.1 461730.0 -66400.0 -0.56 -0.4661 -0.8156 3068143 PK04_095203 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC5CC5)c6ccccc6C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K04 compound treatment 241600.0 -302000.0 -2.57 194730.0 -333000.0 -2.83 -3.8153 -0.9988 3187275 PK04_095204 CN(C)CCCNC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K05 compound treatment 397280.0 -146000.0 -1.24 283410.0 -245000.0 -2.08 -2.3468 -0.9699 3187271 PK04_095205 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K06 compound treatment 397870.0 -146000.0 -1.24 413030.0 -115000.0 -0.98 -1.5658 -0.9931 3186561 PK04_095206 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K07 mock treatment 511930.0 -31400.0 -0.27 586600.0 58500.0 0.5 0.1614 0.2865 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K08 mock treatment 602940.0 59600.0 0.51 546600.0 18500.0 0.16 0.469 0.8843 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K09 compound treatment 571390.0 28000.0 0.24 534950.0 6800.0 0.06 0.2093 0.8536 3068519 PK04_095207 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K10 compound treatment 420210.0 -123000.0 -1.05 543680.0 15500.0 0.13 -0.6478 -0.6134 3068466 PK04_095208 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K11 compound treatment 451250.0 -92100.0 -0.78 570570.0 42400.0 0.36 -0.2997 -0.3476 3068556 PK04_095209 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K12 compound treatment 270520.0 -273000.0 -2.32 298400.0 -230000.0 -1.95 -3.0195 -0.9962 3067978 PK04_095210 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K13 compound treatment 591960.0 48600.0 0.41 537160.0 9010.0 0.08 0.3463 0.8239 3068499 PK04_095211 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K14 compound treatment 479360.0 -64000.0 -0.54 492260.0 -35900.0 -0.3 -0.6004 -0.9622 3068588 PK04_095212 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K15 mock treatment 633030.0 89700.0 0.76 674120.0 146000.0 1.24 1.4149 0.9729 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K16 mock treatment 633600.0 90200.0 0.77 577710.0 49600.0 0.42 0.84 0.9599 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K17 compound treatment 257540.0 -286000.0 -2.43 313070.0 -215000.0 -1.82 -3.0096 -0.99 3068009 PK04_095213 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K18 compound treatment 191470.0 -352000.0 -2.99 140280.0 -388000.0 -3.29 -4.4434 -0.9989 3186498 PK04_095214 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCCN(C)C)c5ccccc5C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K19 compound treatment 527950.0 -15400.0 -0.13 592490.0 64300.0 0.55 0.2931 0.5222 3068472 PK04_095215 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K20 compound treatment 576430.0 33100.0 0.28 539240.0 11100.0 0.09 0.2654 0.8949 3187259 PK04_095216 COCCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K21 compound treatment 554510.0 11100.0 0.09 580930.0 52800.0 0.45 0.3836 0.8381 3187078 PK04_095217 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K22 compound treatment 557440.0 14100.0 0.12 437600.0 -90500.0 -0.77 -0.4585 -0.5899 3068508 PK04_095218 COc1ccccc1CN2[C@H]([C@H](C(=O)NC3CC3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K23 mock treatment 559120.0 15700.0 0.13 527550.0 -599.0 -0.01 0.0911 0.6798 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 K24 mock treatment 475570.0 -67800.0 -0.58 593630.0 65500.0 0.56 -0.0151 -0.0189 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L01 compound treatment 482620.0 -60800.0 -0.52 502560.0 -25600.0 -0.22 -0.519 -0.9257 3187175 PK04_095219 COc1ccccc1CN2[C@H]([C@H](C(=O)NCCCN(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L02 compound treatment 235330.0 -308000.0 -2.62 263130.0 -265000.0 -2.25 -3.4427 -0.9971 3186714 PK04_095220 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L03 compound treatment 395000.0 -148000.0 -1.26 474240.0 -53900.0 -0.46 -1.2159 -0.9057 3067967 PK04_095221 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCc3ccccc3)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L04 compound treatment 464990.0 -78400.0 -0.67 457600.0 -70500.0 -0.6 -0.8947 -0.9985 3186429 PK04_095222 CC(C)CN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L05 compound treatment 499290.0 -44100.0 -0.38 545690.0 17500.0 0.15 -0.16 -0.3965 3068540 PK04_095223 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L06 compound treatment 548820.0 5440.0 0.05 555710.0 27600.0 0.23 0.1981 0.831 3186551 PK04_095224 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L07 mock treatment 482790.0 -60600.0 -0.52 370900.0 -157000.0 -1.33 -1.3077 -0.9144 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L08 mock treatment 595060.0 51700.0 0.44 505010.0 -23100.0 -0.2 0.1721 0.3574 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L09 compound treatment 264800.0 -279000.0 -2.37 213350.0 -315000.0 -2.67 -3.564 -0.9982 3187518 PK04_095225 CN(C)CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L10 compound treatment 606460.0 63100.0 0.54 359520.0 -169000.0 -1.43 -0.632 -0.4137 3068144 PK04_095226 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCc5ccccc5)c6ccccc6C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L11 compound treatment 547170.0 3790.0 0.03 331440.0 -197000.0 -1.67 -1.1571 -0.6933 3187076 PK04_095227 COCCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L12 compound treatment 237930.0 -305000.0 -2.6 226960.0 -301000.0 -2.55 -3.644 -1.0 3068313 PK04_095228 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L13 compound treatment 559010.0 15600.0 0.13 505510.0 -22600.0 -0.19 -0.0417 -0.1787 3187347 PK04_095229 COc1ccc(CCNC(=O)[C@]2(C)[C@@H](N(C(C)C)C(=O)c3ccccc32)c4ccc(CO)cc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L14 compound treatment 572370.0 29000.0 0.25 551430.0 23300.0 0.2 0.3141 0.9939 3068194 PK04_095230 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(C)C)C4=O)c6ccccc6C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L15 mock treatment 399310.0 -144000.0 -1.23 588520.0 60400.0 0.51 -0.5045 -0.3798 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L16 mock treatment 538130.0 -5250.0 -0.04 376060.0 -152000.0 -1.29 -0.9438 -0.7311 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L17 compound treatment 522250.0 -21100.0 -0.18 552530.0 24400.0 0.21 0.0192 0.0699 3068510 PK04_095231 COc1ccccc1CN2[C@H]([C@H](C(=O)NCc3ccccc3)c4ccccc4C2=O)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L18 compound treatment 250570.0 -293000.0 -2.49 267300.0 -261000.0 -2.21 -3.326 -0.9983 3068263 PK04_095232 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C(C)C)[C@@H]2c3ccc(CO)cc3I)Sc4ccc(C)cc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L19 compound treatment 422080.0 -121000.0 -1.03 561280.0 33100.0 0.28 -0.5309 -0.4964 3067958 PK04_095233 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCCN4CCOCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L20 compound treatment 543070.0 -307.0 0.0 528450.0 301.0 0.0 0.0 -0.0101 3068403 PK04_095234 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L21 compound treatment 535400.0 -7980.0 -0.07 534720.0 6570.0 0.06 -0.0086 -0.0976 3187163 PK04_095235 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(F)cc(c3)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L22 compound treatment 487840.0 -55500.0 -0.47 526940.0 -1210.0 -0.01 -0.3413 -0.7223 3186433 PK04_095236 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c5ccc(cc5)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L23 mock treatment 509980.0 -33400.0 -0.28 544930.0 16800.0 0.14 -0.1002 -0.3154 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 L24 mock treatment 548360.0 4980.0 0.04 507680.0 -20500.0 -0.17 -0.0928 -0.5192 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M01 compound treatment 414030.0 -129000.0 -1.1 405210.0 -123000.0 -1.04 -1.5155 -0.9996 3187444 PK04_095237 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M02 compound treatment 536750.0 -6630.0 -0.06 513810.0 -14300.0 -0.12 -0.1259 -0.9389 3068593 PK04_095238 CC(C)N1[C@@H](c2ccc(CO)cc2)[C@@](C)(C(=O)NC3CC3)c4ccccc4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M03 compound treatment 406880.0 -136000.0 -1.16 232370.0 -296000.0 -2.51 -2.5952 -0.9387 3187441 PK04_095239 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M04 compound treatment 503550.0 -39800.0 -0.34 503520.0 -24600.0 -0.21 -0.3873 -0.973 3068649 PK04_095240 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M05 compound treatment 246890.0 -296000.0 -2.52 189480.0 -339000.0 -2.87 -3.8149 -0.9979 3068152 PK04_095241 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M06 compound treatment 354400.0 -189000.0 -1.61 500440.0 -27700.0 -0.24 -1.303 -0.802 3068655 PK04_095242 C[C@]1([C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M07 compound treatment 497720.0 -45700.0 -0.39 552650.0 24500.0 0.21 -0.1277 -0.2899 3068005 PK04_095243 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M08 compound treatment 372190.0 -171000.0 -1.46 470720.0 -57400.0 -0.49 -1.3743 -0.8949 3187084 PK04_095244 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M09 mock treatment 409010.0 -134000.0 -1.14 537370.0 9220.0 0.08 -0.753 -0.6572 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M10 mock treatment 560810.0 17400.0 0.15 576720.0 48600.0 0.41 0.3962 0.9048 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M11 compound treatment 449770.0 -93600.0 -0.8 316560.0 -212000.0 -1.79 -1.8322 -0.9331 3186422 PK04_095245 CCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5I)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M12 compound treatment 272450.0 -271000.0 -2.3 207690.0 -320000.0 -2.72 -3.5519 -0.9966 3068142 PK04_095246 CN(C)CCCNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(C3CCCCC3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M13 mock treatment 421120.0 -122000.0 -1.04 440500.0 -87600.0 -0.74 -1.2612 -0.9865 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M14 mock treatment 612550.0 69200.0 0.59 567840.0 39700.0 0.34 0.6542 0.9649 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M15 compound treatment 579480.0 36100.0 0.31 531860.0 3710.0 0.03 0.2394 0.7755 3068557 PK04_095247 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2C5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M16 compound treatment 572320.0 28900.0 0.25 431310.0 -96800.0 -0.82 -0.4067 -0.4743 3187170 PK04_095248 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2OC)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M17 compound treatment 575580.0 32200.0 0.27 587630.0 59500.0 0.5 0.5505 0.9588 3187431 PK04_095249 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M18 compound treatment 440290.0 -103000.0 -0.88 570450.0 42300.0 0.36 -0.3664 -0.3867 3187074 PK04_095250 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M19 compound treatment 569550.0 26200.0 0.22 470340.0 -57800.0 -0.49 -0.1893 -0.3515 3068552 PK04_095251 CC(C)NC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M20 compound treatment 595780.0 52400.0 0.45 581920.0 53800.0 0.46 0.6378 0.9999 3068014 PK04_095252 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)O)c5ccccc5C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M21 compound treatment 522350.0 -21000.0 -0.18 551710.0 23600.0 0.2 0.0148 0.0553 3187086 PK04_095253 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M22 compound treatment 551570.0 8190.0 0.07 496320.0 -31800.0 -0.27 -0.1416 -0.5079 3187428 PK04_095254 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NC5CC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M23 compound treatment 445320.0 -98100.0 -0.83 482720.0 -45400.0 -0.39 -0.8624 -0.9385 3187081 PK04_095255 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 M24 compound treatment 490640.0 -52700.0 -0.45 423890.0 -104000.0 -0.88 -0.9426 -0.9505 3068003 PK04_095256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N01 compound treatment 459680.0 -83700.0 -0.71 488800.0 -39300.0 -0.33 -0.7395 -0.9404 3187360 PK04_095257 C[C@]1([C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N02 compound treatment 441670.0 -102000.0 -0.87 543690.0 15500.0 0.13 -0.5186 -0.5925 3068231 PK04_095258 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N03 compound treatment 547040.0 3660.0 0.03 497200.0 -30900.0 -0.26 -0.1636 -0.6188 3068544 PK04_095259 CC(C)NC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N04 compound treatment 323590.0 -220000.0 -1.87 297820.0 -230000.0 -1.95 -2.7037 -0.9998 3187527 PK04_095260 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)O)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N05 compound treatment 551630.0 8250.0 0.07 515410.0 -12700.0 -0.11 -0.0268 -0.2077 3187260 PK04_095261 CCCNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N06 compound treatment 253760.0 -290000.0 -2.46 248660.0 -279000.0 -2.37 -3.4186 -0.9998 3186724 PK04_095262 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N07 compound treatment 545370.0 1990.0 0.02 431490.0 -96700.0 -0.82 -0.5678 -0.6923 3068501 PK04_095263 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N08 compound treatment 503100.0 -40300.0 -0.34 442720.0 -85400.0 -0.72 -0.7547 -0.9415 3186871 PK04_095264 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N09 mock treatment 566630.0 23300.0 0.2 499630.0 -28500.0 -0.24 -0.0312 -0.0998 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N10 mock treatment 539870.0 -3510.0 -0.03 542260.0 14100.0 0.12 0.0635 0.5151 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N11 compound treatment 563950.0 20600.0 0.18 558890.0 30700.0 0.26 0.3082 0.9812 3187070 PK04_095265 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N12 compound treatment 270190.0 -273000.0 -2.32 275680.0 -252000.0 -2.14 -3.1577 -0.9992 3186804 PK04_095266 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N13 mock treatment 586290.0 42900.0 0.37 520010.0 -8140.0 -0.07 0.2093 0.5634 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N14 mock treatment 559410.0 16000.0 0.14 593970.0 65800.0 0.56 0.4913 0.8547 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N15 compound treatment 301020.0 -242000.0 -2.06 315330.0 -213000.0 -1.81 -2.7344 -0.9978 3186424 PK04_095267 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCCN6CCOCC6)c7ccc(cc7)[N+](=O)[O-])c(I)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N16 compound treatment 477470.0 -65900.0 -0.56 511130.0 -17000.0 -0.14 -0.4985 -0.8611 3068226 PK04_095268 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N17 compound treatment 587310.0 43900.0 0.37 537150.0 9000.0 0.08 0.3183 0.8343 3068455 PK04_095269 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N18 compound treatment 350920.0 -192000.0 -1.64 450720.0 -77400.0 -0.66 -1.6222 -0.9195 3068137 PK04_095270 CN(C)CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N19 compound treatment 536270.0 -7110.0 -0.06 556190.0 28000.0 0.24 0.1254 0.5111 3068647 PK04_095271 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCC(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N20 compound treatment 412090.0 -131000.0 -1.12 366080.0 -162000.0 -1.37 -1.7619 -0.9947 3186492 PK04_095272 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N21 compound treatment 444270.0 -99100.0 -0.84 521340.0 -6810.0 -0.06 -0.637 -0.7538 3067959 PK04_095273 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-])cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N22 compound treatment 476480.0 -66900.0 -0.57 474090.0 -54100.0 -0.46 -0.7267 -0.9943 3187526 PK04_095274 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)O)c3ccc(cc3)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N23 compound treatment 501090.0 -42300.0 -0.36 541320.0 13200.0 0.11 -0.1754 -0.4656 3068468 PK04_095275 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 N24 compound treatment 484700.0 -58700.0 -0.5 504890.0 -23300.0 -0.2 -0.4925 -0.9175 3068222 PK04_095276 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O01 compound treatment 424230.0 -119000.0 -1.01 387360.0 -141000.0 -1.19 -1.5612 -0.9967 3068590 PK04_095277 CC(C)NC(=O)[C@H]1[C@@H](N(CC2(CC3CC4CC(C3)C2)C4)C(=O)c5ccccc15)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O02 compound treatment 198780.0 -345000.0 -2.93 149160.0 -379000.0 -3.21 -4.3462 -0.9989 3067977 PK04_095278 COCCCNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O03 compound treatment 468980.0 -74400.0 -0.63 471840.0 -56300.0 -0.48 -0.7853 -0.9904 3068512 PK04_095279 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(F)(F)F)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O04 compound treatment 480000.0 -63400.0 -0.54 334240.0 -194000.0 -1.64 -1.5443 -0.8922 3068637 PK04_095280 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O05 compound treatment 428360.0 -115000.0 -0.98 455520.0 -72600.0 -0.62 -1.1275 -0.9751 3068459 PK04_095281 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2Cc4cc(cc(c4)C(F)(F)F)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O06 compound treatment 435750.0 -108000.0 -0.92 482270.0 -45900.0 -0.39 -0.9226 -0.9274 3187520 PK04_095282 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O07 compound treatment 494100.0 -49300.0 -0.42 458400.0 -69700.0 -0.59 -0.7148 -0.9858 3186989 PK04_095283 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O08 compound treatment 475050.0 -68300.0 -0.58 440480.0 -87700.0 -0.74 -0.9369 -0.9926 3187364 PK04_095284 C[C@]1([C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O09 compound treatment 497560.0 -45800.0 -0.39 418820.0 -109000.0 -0.93 -0.9314 -0.9258 3068604 PK04_095285 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O10 compound treatment 486080.0 -57300.0 -0.49 522200.0 -5950.0 -0.05 -0.3804 -0.7762 3187362 PK04_095286 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O11 mock treatment 511090.0 -32300.0 -0.27 523000.0 -5150.0 -0.04 -0.2251 -0.8094 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O12 mock treatment 494260.0 -49100.0 -0.42 510000.0 -18100.0 -0.15 -0.4043 -0.908 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O13 compound treatment 533760.0 -9620.0 -0.08 535150.0 7000.0 0.06 -0.0159 -0.1568 3068644 PK04_095287 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O14 compound treatment 425120.0 -118000.0 -1.01 489770.0 -38400.0 -0.33 -0.9416 -0.8905 3068464 PK04_095288 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O15 compound treatment 191520.0 -352000.0 -2.99 261760.0 -266000.0 -2.26 -3.7145 -0.9904 3187516 PK04_095289 OCc1ccc(cc1)[C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCc6ccccc6)c7ccc(cc7)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O16 compound treatment 513120.0 -30300.0 -0.26 427760.0 -100000.0 -0.85 -0.7842 -0.8815 3187164 PK04_095290 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(F)cc(c5)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O17 compound treatment 502950.0 -40400.0 -0.34 525670.0 -2480.0 -0.02 -0.2581 -0.7489 3187177 PK04_095291 CC(C)CNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O18 compound treatment 304960.0 -238000.0 -2.03 376530.0 -152000.0 -1.29 -2.3436 -0.9758 3068546 PK04_095292 CN(C)CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O19 compound treatment 406280.0 -137000.0 -1.17 505660.0 -22500.0 -0.19 -0.9596 -0.812 3187256 PK04_095293 CC(C)CNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O20 compound treatment 431600.0 -112000.0 -0.95 484070.0 -44100.0 -0.37 -0.9368 -0.9168 3187088 PK04_095294 COCCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2Cl)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O21 compound treatment 419860.0 -124000.0 -1.05 454570.0 -73600.0 -0.62 -1.1844 -0.9691 3186494 PK04_095295 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCC(C)C)c5ccccc5C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O22 compound treatment 463600.0 -79800.0 -0.68 484180.0 -44000.0 -0.37 -0.7436 -0.9603 3187161 PK04_095296 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O23 compound treatment 416640.0 -127000.0 -1.08 441680.0 -86500.0 -0.73 -1.281 -0.9824 3187267 PK04_095297 CC(C)CNC(=O)[C@H]1[C@@H](N(C2CCCCC2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 O24 compound treatment 344430.0 -199000.0 -1.69 465690.0 -62500.0 -0.53 -1.5714 -0.8861 3068502 PK04_095298 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P01 compound treatment 286880.0 -256000.0 -2.18 326420.0 -202000.0 -1.71 -2.753 -0.9928 3068591 PK04_095299 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2CC4(CC5CC6CC(C5)C4)C6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P02 compound treatment 332920.0 -210000.0 -1.79 357190.0 -171000.0 -1.45 -2.2915 -0.9945 3187521 PK04_095300 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P03 compound treatment 301000.0 -242000.0 -2.06 305610.0 -223000.0 -1.89 -2.7929 -0.999 3186990 PK04_095301 COc1ccc(CCNC(=O)[C@H]2[C@@H](N(Cc3ccccc3)C(=O)c4ccccc24)c5ccc(CO)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P04 compound treatment 293380.0 -250000.0 -2.13 323800.0 -204000.0 -1.73 -2.7296 -0.9948 3186985 PK04_095302 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P05 compound treatment 203090.0 -340000.0 -2.89 181070.0 -347000.0 -2.94 -4.1289 -1.0 3067579 PK04_095303 OCc1ccc([C@H]2N(CC3(CC4CC5CC(C4)C3)C5)C(=O)C[C@@]2(C(=O)NCC(F)(F)F)c6ccc(cc6)[N+](=O)[O-])c(I)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P06 compound treatment 322080.0 -221000.0 -1.88 227910.0 -300000.0 -2.55 -3.1321 -0.9889 3186975 PK04_095304 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P07 compound treatment 401290.0 -142000.0 -1.21 363850.0 -164000.0 -1.39 -1.8402 -0.9975 3068548 PK04_095305 CC(C)CNC(=O)[C@H]1[C@@H](N(C(C)C)C(=O)c2ccccc12)c3ccc(CO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P08 compound treatment 229890.0 -313000.0 -2.67 379540.0 -149000.0 -1.26 -2.7772 -0.9415 3067563 PK04_095306 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(CCN5CCOCC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P09 compound treatment 308030.0 -235000.0 -2.0 204900.0 -323000.0 -2.74 -3.3546 -0.9881 3067961 PK04_095307 OCc1ccc(cc1)[C@H]2N(C3CCCCC3)C(=O)C[C@@]2(C(=O)NCc4ccccc4)c5ccc(cc5)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P10 compound treatment 284450.0 -259000.0 -2.2 262680.0 -265000.0 -2.25 -3.1499 -0.9999 3068015 PK04_095308 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P11 mock treatment 337030.0 -206000.0 -1.76 325520.0 -203000.0 -1.72 -2.4567 -0.9999 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P12 mock treatment 295950.0 -247000.0 -2.1 301230.0 -227000.0 -1.92 -2.8495 -0.999 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P13 compound treatment 210520.0 -333000.0 -2.83 265480.0 -263000.0 -2.23 -3.5779 -0.993 3187510 PK04_095309 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P14 compound treatment 270670.0 -273000.0 -2.32 237540.0 -291000.0 -2.47 -3.3836 -0.9995 3186495 PK04_095310 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NCCN5CCOCC5)c6ccccc6C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P15 compound treatment 290350.0 -253000.0 -2.15 306470.0 -222000.0 -1.88 -2.8518 -0.9977 3187437 PK04_095311 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P16 compound treatment 287810.0 -256000.0 -2.17 375580.0 -153000.0 -1.29 -2.4525 -0.9693 3186625 PK04_095312 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C(C)C)C4=O)c6ccccc6C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P17 compound treatment 295680.0 -248000.0 -2.11 292260.0 -236000.0 -2.0 -2.9049 -0.9997 3068541 PK04_095313 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCCN3CCOCC3)c4ccccc4C(=O)N2C5Cc6ccccc6C5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P18 compound treatment 263360.0 -280000.0 -2.38 208090.0 -320000.0 -2.71 -3.6042 -0.9979 3186878 PK04_095314 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NC6CC6)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P19 compound treatment 172320.0 -371000.0 -3.16 188200.0 -340000.0 -2.88 -4.2712 -0.999 3187513 PK04_095315 CC(C)CNC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P20 compound treatment 171080.0 -372000.0 -3.17 152550.0 -376000.0 -3.19 -4.4925 -1.0 3068271 PK04_095316 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCc6ccccc6)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P21 compound treatment 164530.0 -379000.0 -3.22 160320.0 -368000.0 -3.12 -4.4853 -0.9999 3068008 PK04_095317 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P22 compound treatment 158930.0 -384000.0 -3.27 142500.0 -386000.0 -3.27 -4.6259 -1.0 3068262 PK04_095318 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P23 compound treatment 231130.0 -312000.0 -2.66 302730.0 -225000.0 -1.91 -3.2304 -0.987 3068469 PK04_095319 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2095 P24 compound treatment 157680.0 -386000.0 -3.28 152000.0 -376000.0 -3.19 -4.5764 -0.9999 3186794 PK04_095320 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A01 compound treatment 482210.0 -60000.0 -0.51 517200.0 -43800.0 -0.37 -0.6238 -0.9879 3186490 PK04_096001 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A02 compound treatment 470160.0 -72000.0 -0.61 514600.0 -46400.0 -0.39 -0.7119 -0.9771 3186641 PK04_096002 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A03 compound treatment 217790.0 -324000.0 -2.76 237380.0 -324000.0 -2.75 -3.8929 -1.0 3068261 PK04_096003 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A04 compound treatment 482590.0 -59600.0 -0.51 289990.0 -271000.0 -2.3 -1.9844 -0.8428 3186971 PK04_096004 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A05 compound treatment 321810.0 -220000.0 -1.87 185920.0 -375000.0 -3.18 -3.5758 -0.9682 3186883 PK04_096005 COCCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A06 compound treatment 228210.0 -314000.0 -2.67 231790.0 -329000.0 -2.79 -3.8637 -0.9998 3068309 PK04_096006 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A07 compound treatment 216710.0 -325000.0 -2.77 232200.0 -329000.0 -2.79 -3.9304 -1.0 3186716 PK04_096007 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2I)Sc3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A08 compound treatment 445060.0 -97100.0 -0.83 418670.0 -142000.0 -1.21 -1.4383 -0.9829 3068367 PK04_096008 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)Sc6ccc(C)cc6)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A09 compound treatment 456970.0 -85200.0 -0.73 508360.0 -52700.0 -0.45 -0.8287 -0.9729 3068224 PK04_096009 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A10 compound treatment 348240.0 -194000.0 -1.65 460720.0 -100000.0 -0.85 -1.7685 -0.9526 3186633 PK04_096010 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5C(F)(F)F)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A11 compound treatment 467620.0 -74600.0 -0.63 499220.0 -61800.0 -0.52 -0.8194 -0.9955 3186986 PK04_096011 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A12 compound treatment 355950.0 -186000.0 -1.58 518190.0 -42800.0 -0.36 -1.3774 -0.8473 3186640 PK04_096012 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A13 mock treatment 448160.0 -94000.0 -0.8 498880.0 -62200.0 -0.53 -0.9385 -0.9795 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A14 mock treatment 540590.0 -1610.0 -0.01 504420.0 -56600.0 -0.48 -0.3493 -0.727 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A15 compound treatment 485610.0 -56600.0 -0.48 476450.0 -84600.0 -0.72 -0.8478 -0.9812 3186881 PK04_096013 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A16 compound treatment 250200.0 -292000.0 -2.48 232450.0 -329000.0 -2.79 -3.7275 -0.9984 3186790 PK04_096014 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A17 compound treatment 510910.0 -31300.0 -0.27 532640.0 -28400.0 -0.24 -0.3586 -0.9988 3186485 PK04_096015 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A18 compound treatment 223360.0 -319000.0 -2.71 216820.0 -344000.0 -2.92 -3.9827 -0.9993 3186802 PK04_096016 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A19 compound treatment 478170.0 -64000.0 -0.54 524050.0 -37000.0 -0.31 -0.607 -0.9656 3068405 PK04_096017 CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A20 compound treatment 542290.0 86.0 0.0 414840.0 -146000.0 -1.24 -0.8764 -0.7067 3068141 PK04_096018 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A21 compound treatment 457970.0 -84200.0 -0.72 501280.0 -59800.0 -0.51 -0.8651 -0.9856 3186624 PK04_096019 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5OC)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A22 compound treatment 510240.0 -32000.0 -0.27 513470.0 -47600.0 -0.4 -0.4776 -0.9816 3068200 PK04_096020 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCCN(C)C)C4=O)c6ccccc6C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A23 compound treatment 492190.0 -50000.0 -0.43 527880.0 -33200.0 -0.28 -0.4997 -0.9798 3068358 PK04_096021 CC(C)CNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 A24 compound treatment 450650.0 -91600.0 -0.78 475060.0 -86000.0 -0.73 -1.0664 -0.9995 3068371 PK04_096022 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B01 compound treatment 518410.0 -23800.0 -0.2 506400.0 -54600.0 -0.46 -0.4708 -0.931 3187511 PK04_096023 CC(C)N1[C@H](c2ccc(CO)cc2)[C@](CC1=O)(C(=O)NCC(F)(F)F)c3ccc(cc3)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B02 compound treatment 544440.0 2240.0 0.02 520030.0 -41000.0 -0.35 -0.2325 -0.6674 3187030 PK04_096024 OCCCc1cc[n+](Cc2cccc(OC(F)(F)F)c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B03 compound treatment 468860.0 -73300.0 -0.62 474500.0 -86500.0 -0.73 -0.9603 -0.9967 3187169 PK04_096025 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B04 compound treatment 529320.0 -12900.0 -0.11 490660.0 -70400.0 -0.6 -0.4996 -0.8232 3068853 PK04_096026 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B05 compound treatment 502210.0 -40000.0 -0.34 554500.0 -6540.0 -0.06 -0.2798 -0.8116 3068457 PK04_096027 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCc3ccccc3)c4ccccc4C(=O)N2Cc5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B06 compound treatment 507550.0 -34700.0 -0.29 534250.0 -26800.0 -0.23 -0.3691 -0.9917 3068854 PK04_096028 C[n+]1ccc2ccc(O)cc2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B07 compound treatment 446240.0 -96000.0 -0.82 468970.0 -92100.0 -0.78 -1.1295 -0.9998 3187352 PK04_096029 Cc1ccc(nc1)N2[C@@H](c3ccc(CO)cc3)[C@@](C)(C(=O)NCCN4CCOCC4)c5ccccc5C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B08 compound treatment 505440.0 -36800.0 -0.31 516000.0 -45000.0 -0.38 -0.4913 -0.9951 3187112 PK04_096030 COc1cc2CC[N+](=Cc2cc1O)Cc3cc4OCOc4cc3Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B09 compound treatment 474990.0 -67200.0 -0.57 502880.0 -58200.0 -0.49 -0.7532 -0.9973 3068505 PK04_096031 CC(C)NC(=O)[C@H]1[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B10 compound treatment 539240.0 -2960.0 -0.03 536480.0 -24600.0 -0.21 -0.1651 -0.787 3068855 PK04_096032 C[n+]1ccc(CCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B11 compound treatment 508160.0 -34000.0 -0.29 481530.0 -79500.0 -0.67 -0.6817 -0.9287 3068374 PK04_096033 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B12 compound treatment 428500.0 -114000.0 -0.97 397600.0 -163000.0 -1.39 -1.6643 -0.9845 3187113 PK04_096034 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C=C)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B13 mock treatment 558730.0 16500.0 0.14 560000.0 -1040.0 -0.01 0.0932 0.6617 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B14 mock treatment 488080.0 -54100.0 -0.46 569470.0 8430.0 0.07 -0.275 -0.5901 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B15 compound treatment 586150.0 43900.0 0.37 550240.0 -10800.0 -0.09 0.1996 0.5186 3187255 PK04_096035 COCCCNC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B16 compound treatment 429040.0 -113000.0 -0.96 419890.0 -141000.0 -1.2 -1.5274 -0.9942 3068856 PK04_096036 Oc1ccc2cc[n+](Cc3sc4ccccc4c3Cl)cc2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B17 compound treatment 581630.0 39400.0 0.34 524740.0 -36300.0 -0.31 0.0195 0.0428 3068608 PK04_096037 CC(C)NC(=O)[C@]1(C)[C@@H](N(Cc2ccc(OC(F)(F)F)cc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B18 compound treatment 228020.0 -314000.0 -2.67 235800.0 -325000.0 -2.76 -3.8408 -0.9999 3187114 PK04_096038 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C5CC5)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B19 compound treatment 559950.0 17700.0 0.15 578200.0 17200.0 0.15 0.2097 0.9998 3187171 PK04_096039 COc1ccccc1CN2[C@H]([C@H](C(=O)NCC(C)C)c3ccccc3C2=O)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B20 compound treatment 292640.0 -250000.0 -2.12 313490.0 -248000.0 -2.1 -2.9861 -1.0 3068857 PK04_096040 OCCCc1cc[n+](Cc2ccc(o2)[N+](=O)[O-])cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B21 compound treatment 558470.0 16300.0 0.14 538970.0 -22100.0 -0.19 -0.0345 -0.1482 3068424 PK04_096041 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B22 compound treatment 445070.0 -97100.0 -0.83 484080.0 -77000.0 -0.65 -1.0459 -0.9932 3187115 PK04_096042 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(C)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B23 compound treatment 509540.0 -32700.0 -0.28 543230.0 -17800.0 -0.15 -0.3033 -0.9589 3187072 PK04_096043 CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 B24 compound treatment 425840.0 -116000.0 -0.99 478900.0 -82100.0 -0.7 -1.1927 -0.9852 3187116 PK04_096044 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C01 compound treatment 472120.0 -70100.0 -0.6 504520.0 -56500.0 -0.48 -0.7606 -0.9942 3068218 PK04_096045 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C02 compound treatment 526760.0 -15400.0 -0.13 353200.0 -208000.0 -1.76 -1.3395 -0.7577 3186566 PK04_096046 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C03 compound treatment 448720.0 -93500.0 -0.8 412650.0 -148000.0 -1.26 -1.4524 -0.9755 3186549 PK04_096047 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C04 compound treatment 214520.0 -328000.0 -2.79 217350.0 -344000.0 -2.92 -4.0327 -0.9997 3186726 PK04_096048 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C05 compound treatment 215620.0 -327000.0 -2.78 228840.0 -332000.0 -2.82 -3.9572 -1.0 3186792 PK04_096049 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C06 compound treatment 408980.0 -133000.0 -1.13 400960.0 -160000.0 -1.36 -1.7616 -0.996 3186987 PK04_096050 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C07 compound treatment 230940.0 -311000.0 -2.65 212580.0 -348000.0 -2.96 -3.9625 -0.9985 3068275 PK04_096051 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C08 compound treatment 450440.0 -91800.0 -0.78 480350.0 -80700.0 -0.68 -1.036 -0.9978 3186560 PK04_096052 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C09 compound treatment 314170.0 -228000.0 -1.94 307520.0 -254000.0 -2.15 -2.8924 -0.9987 3068147 PK04_096053 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C10 compound treatment 400210.0 -142000.0 -1.21 488060.0 -73000.0 -0.62 -1.2919 -0.9518 3186976 PK04_096054 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C11 mock treatment 379440.0 -163000.0 -1.38 345670.0 -215000.0 -1.83 -2.2709 -0.9907 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C12 mock treatment 499290.0 -42900.0 -0.37 534770.0 -26300.0 -0.22 -0.4157 -0.9719 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C13 compound treatment 445020.0 -97200.0 -0.83 507250.0 -53800.0 -0.46 -0.9072 -0.9607 3186974 PK04_096055 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C14 compound treatment 447600.0 -94600.0 -0.8 511840.0 -49200.0 -0.42 -0.8642 -0.9532 3186876 PK04_096056 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C15 mock treatment 509090.0 -33100.0 -0.28 471110.0 -89900.0 -0.76 -0.7386 -0.9083 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C16 mock treatment 431800.0 -110000.0 -0.94 465690.0 -95300.0 -0.81 -1.236 -0.9972 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C17 compound treatment 513450.0 -28800.0 -0.24 378020.0 -183000.0 -1.55 -1.2707 -0.8085 3186553 PK04_096057 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C18 compound treatment 510480.0 -31700.0 -0.27 510850.0 -50200.0 -0.43 -0.4919 -0.9758 3186634 PK04_096058 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C19 compound treatment 378460.0 -164000.0 -1.39 523050.0 -38000.0 -0.32 -1.2129 -0.8483 3186638 PK04_096059 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(Cc5ccccc5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C20 compound treatment 503400.0 -38800.0 -0.33 506430.0 -54600.0 -0.46 -0.561 -0.9862 3068219 PK04_096060 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C21 compound treatment 389760.0 -152000.0 -1.3 467900.0 -93100.0 -0.79 -1.4757 -0.9718 3068151 PK04_096061 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C22 compound treatment 442480.0 -99700.0 -0.85 504380.0 -56700.0 -0.48 -0.9397 -0.9638 3068158 PK04_096062 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CC(F)(F)F)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C23 compound treatment 230090.0 -312000.0 -2.66 250650.0 -310000.0 -2.63 -3.7393 -1.0 3186800 PK04_096063 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 C24 compound treatment 392740.0 -149000.0 -1.27 417920.0 -143000.0 -1.21 -1.7575 -0.9997 3068376 PK04_096064 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D01 compound treatment 525310.0 -16900.0 -0.14 481350.0 -79700.0 -0.68 -0.5796 -0.8387 3068407 PK04_096065 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D02 compound treatment 300960.0 -241000.0 -2.05 287310.0 -274000.0 -2.32 -3.0931 -0.9981 3187117 PK04_096066 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D03 compound treatment 474670.0 -67500.0 -0.57 424420.0 -137000.0 -1.16 -1.2257 -0.9476 3187274 PK04_096067 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2CC5(CC6CC7CC(C6)C5)C7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D04 compound treatment 445280.0 -96900.0 -0.82 434950.0 -126000.0 -1.07 -1.3393 -0.9917 3068858 PK04_096068 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C=C)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D05 compound treatment 421220.0 -121000.0 -1.03 514590.0 -46400.0 -0.39 -1.0064 -0.9132 3187075 PK04_096069 CN(C)CCCNC(=O)[C@H]1[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D06 compound treatment 510460.0 -31700.0 -0.27 495710.0 -65300.0 -0.55 -0.5828 -0.9454 3187118 PK04_096070 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D07 compound treatment 422620.0 -120000.0 -1.02 435490.0 -126000.0 -1.06 -1.4724 -0.9997 3068634 PK04_096071 CC(C)CNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D08 compound treatment 390590.0 -152000.0 -1.29 395630.0 -165000.0 -1.4 -1.9042 -0.9991 3068859 PK04_096072 OCc1ccc(cc1)c2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D09 compound treatment 276410.0 -266000.0 -2.26 197050.0 -364000.0 -3.09 -3.7822 -0.9883 3067975 PK04_096073 CC(C)NC(=O)[C@]1(CC(=O)N(CC2(CC3CC4CC(C3)C2)C4)[C@@H]1c5ccc(CO)cc5)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D10 compound treatment 508160.0 -34000.0 -0.29 527330.0 -33700.0 -0.29 -0.407 -1.0 3068860 PK04_096074 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D11 mock treatment 555080.0 12900.0 0.11 498480.0 -62600.0 -0.53 -0.2978 -0.5496 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D12 mock treatment 526260.0 -15900.0 -0.14 566830.0 5790.0 0.05 -0.0612 -0.4239 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D13 compound treatment 515120.0 -27100.0 -0.23 487370.0 -73700.0 -0.62 -0.6048 -0.9081 3187429 PK04_096075 C[C@]1([C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4)C(=O)NCCN5CCOCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D14 compound treatment 554150.0 11900.0 0.1 404260.0 -157000.0 -1.33 -0.8685 -0.6512 3187119 PK04_096076 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D15 mock treatment 574970.0 32800.0 0.28 557290.0 -3750.0 -0.03 0.1746 0.6225 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D16 mock treatment 548400.0 6200.0 0.05 544180.0 -16900.0 -0.14 -0.0638 -0.4189 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D17 compound treatment 514000.0 -28200.0 -0.24 538680.0 -22400.0 -0.19 -0.3038 -0.9932 3187348 PK04_096077 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(C)C)C(=O)c2ccccc21)c3ccc(CO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D18 compound treatment 477600.0 -64600.0 -0.55 478790.0 -82200.0 -0.7 -0.882 -0.993 3068861 PK04_096078 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C4CC4)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D19 compound treatment 566300.0 24100.0 0.2 568770.0 7730.0 0.07 0.1913 0.889 3187354 PK04_096079 CC(C)NC(=O)[C@]1(C)[C@@H](N(C(=O)c2ccccc21)c3ccc(C)cn3)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D20 compound treatment 478680.0 -63500.0 -0.54 499680.0 -61400.0 -0.52 -0.7502 -0.9998 3187120 PK04_096080 OCc1ccc(cc1)c2cc[n+](Cc3sc4ccccc4c3Cl)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D21 compound treatment 494110.0 -48100.0 -0.41 551170.0 -9870.0 -0.08 -0.3485 -0.8345 3187433 PK04_096081 CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D22 compound treatment 538160.0 -4040.0 -0.03 536730.0 -24300.0 -0.21 -0.1701 -0.8138 3068862 PK04_096082 COc1cc2CCN(C)C(C)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D23 compound treatment 480980.0 -61200.0 -0.52 439860.0 -121000.0 -1.03 -1.0951 -0.9504 3068462 PK04_096083 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NC3CC3)c4ccccc4C(=O)N2Cc5ccccc5C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 D24 compound treatment 375200.0 -167000.0 -1.42 356490.0 -205000.0 -1.74 -2.2315 -0.9951 3187121 PK04_096084 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E01 mock treatment 524050.0 -18200.0 -0.15 544440.0 -16600.0 -0.14 -0.2087 -0.9989 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E02 mock treatment 562620.0 20400.0 0.17 559570.0 -1470.0 -0.01 0.114 0.6548 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E03 compound treatment 218930.0 -323000.0 -2.75 233150.0 -328000.0 -2.78 -3.9114 -1.0 3186708 PK04_096085 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E04 compound treatment 228970.0 -313000.0 -2.66 256680.0 -304000.0 -2.58 -3.7099 -0.9999 3186710 PK04_096086 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E05 compound treatment 440860.0 -101000.0 -0.86 489120.0 -71900.0 -0.61 -1.041 -0.9857 3186888 PK04_096087 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E06 compound treatment 519170.0 -23000.0 -0.2 262770.0 -298000.0 -2.53 -1.9276 -0.7596 3186565 PK04_096088 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(Cc7ccccc7)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E07 compound treatment 529790.0 -12400.0 -0.11 503750.0 -57300.0 -0.49 -0.4183 -0.8411 3186983 PK04_096089 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E08 compound treatment 556030.0 13800.0 0.12 434830.0 -126000.0 -1.07 -0.6738 -0.6257 3067581 PK04_096090 CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E09 mock treatment 552530.0 10300.0 0.09 559950.0 -1090.0 -0.01 0.0556 0.6296 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E10 mock treatment 547420.0 5220.0 0.04 565720.0 4680.0 0.04 0.0595 0.9985 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E11 compound treatment 269770.0 -272000.0 -2.32 260280.0 -301000.0 -2.55 -3.4428 -0.9989 3186717 PK04_096091 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E12 compound treatment 568340.0 26100.0 0.22 544820.0 -16200.0 -0.14 0.06 0.2293 3068221 PK04_096092 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E13 compound treatment 267270.0 -275000.0 -2.34 229690.0 -331000.0 -2.81 -3.6414 -0.9958 3068273 PK04_096093 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E14 compound treatment 518880.0 -23300.0 -0.2 546930.0 -14100.0 -0.12 -0.2249 -0.9707 3068377 PK04_096094 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E15 compound treatment 477920.0 -64300.0 -0.55 503390.0 -57600.0 -0.49 -0.7325 -0.9984 3068408 PK04_096095 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCc5ccccc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E16 compound treatment 537920.0 -4280.0 -0.04 555330.0 -5710.0 -0.05 -0.06 -0.9902 3186635 PK04_096096 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E17 mock treatment 536320.0 -5880.0 -0.05 581790.0 20800.0 0.18 0.0891 0.4868 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E18 mock treatment 592600.0 50400.0 0.43 553860.0 -7180.0 -0.06 0.2601 0.6007 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E19 compound treatment 230280.0 -312000.0 -2.65 274200.0 -287000.0 -2.43 -3.5969 -0.9991 3186791 PK04_096097 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E20 compound treatment 549180.0 6980.0 0.06 483840.0 -77200.0 -0.65 -0.4211 -0.6404 3068233 PK04_096098 CC(C)N1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E21 compound treatment 243150.0 -299000.0 -2.54 265390.0 -296000.0 -2.51 -3.5723 -1.0 3186719 PK04_096099 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)Sc6ccc(C)cc6)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E22 compound treatment 248640.0 -294000.0 -2.5 230500.0 -331000.0 -2.8 -3.7486 -0.9983 3186789 PK04_096100 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E23 compound treatment 247600.0 -295000.0 -2.51 222600.0 -338000.0 -2.87 -3.8022 -0.9977 3186803 PK04_096101 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 E24 compound treatment 207840.0 -334000.0 -2.84 242660.0 -318000.0 -2.7 -3.9211 -0.9997 3186711 PK04_096102 CN(C)CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F01 mock treatment 507000.0 -35200.0 -0.3 502200.0 -58800.0 -0.5 -0.5647 -0.9702 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F02 mock treatment 558370.0 16200.0 0.14 605800.0 44800.0 0.38 0.3658 0.9056 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F03 compound treatment 469920.0 -72300.0 -0.61 463530.0 -97500.0 -0.83 -1.0197 -0.9893 3068521 PK04_096103 CCCNC(=O)[C@H]1[C@@H](N(C2Cc3ccccc3C2)C(=O)c4ccccc14)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F04 compound treatment 529190.0 -13000.0 -0.11 580020.0 19000.0 0.16 0.0356 0.1821 3187122 PK04_096104 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F05 compound treatment 371000.0 -171000.0 -1.46 490490.0 -70500.0 -0.6 -1.453 -0.9228 3068461 PK04_096105 CCCNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F06 compound treatment 386400.0 -156000.0 -1.33 269950.0 -291000.0 -2.47 -2.6832 -0.9575 3068863 PK04_096106 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F07 compound treatment 535770.0 -6430.0 -0.05 337090.0 -224000.0 -1.9 -1.382 -0.7272 3187077 PK04_096107 CC(C)CNC(=O)[C@H]1[C@@H](N(Cc2ccccc2C(F)(F)F)C(=O)c3ccccc13)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F08 compound treatment 418440.0 -124000.0 -1.05 438800.0 -122000.0 -1.04 -1.4777 -1.0 3187123 PK04_096108 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CN5CCCC5)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F09 mock treatment 382110.0 -160000.0 -1.36 599060.0 38000.0 0.32 -0.735 -0.5251 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F10 mock treatment 545240.0 3040.0 0.03 552280.0 -8760.0 -0.07 -0.0343 -0.4356 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F11 compound treatment 373340.0 -169000.0 -1.44 476440.0 -84600.0 -0.72 -1.5232 -0.9486 3187438 PK04_096109 CN(C)CCCNC(=O)[C@]1(C)[C@@H](N(Cc2ccccc2)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F12 compound treatment 394720.0 -147000.0 -1.25 323630.0 -237000.0 -2.01 -2.3112 -0.9741 3187124 PK04_096110 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OC)c3ccc(CO)cc3)c4cccs4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F13 compound treatment 358130.0 -184000.0 -1.57 430420.0 -131000.0 -1.11 -1.8908 -0.9856 3068559 PK04_096111 OCc1ccc(cc1)[C@H]2[C@H](C(=O)NCC(F)(F)F)c3ccccc3C(=O)N2C4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F14 compound treatment 402180.0 -140000.0 -1.19 467760.0 -93300.0 -0.79 -1.4018 -0.9802 3068864 PK04_096112 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F15 compound treatment 264800.0 -277000.0 -2.36 266370.0 -295000.0 -2.5 -3.4362 -0.9996 3186801 PK04_096113 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F16 compound treatment 368480.0 -174000.0 -1.48 380720.0 -180000.0 -1.53 -2.1266 -0.9999 3187125 PK04_096114 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F17 mock treatment 567920.0 25700.0 0.22 537550.0 -23500.0 -0.2 0.0138 0.0467 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F18 mock treatment 591200.0 49000.0 0.42 584660.0 23600.0 0.2 0.4364 0.9437 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F19 compound treatment 256910.0 -285000.0 -2.43 217760.0 -343000.0 -2.91 -3.7752 -0.9959 3186718 PK04_096115 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NC6CC6)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F20 compound treatment 464360.0 -77800.0 -0.66 476930.0 -84100.0 -0.71 -0.9728 -0.9993 3068865 PK04_096116 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)c4cccs4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F21 compound treatment 414640.0 -128000.0 -1.09 262880.0 -298000.0 -2.53 -2.5558 -0.9286 3067569 PK04_096117 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F22 compound treatment 476160.0 -66000.0 -0.56 438890.0 -122000.0 -1.04 -1.1299 -0.9587 3187126 PK04_096118 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C=C)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F23 compound treatment 464200.0 -78000.0 -0.66 494400.0 -66600.0 -0.57 -0.8689 -0.9968 3068643 PK04_096119 COCCCNC(=O)[C@]1(C)[C@@H](N(Cc2cc(F)cc(c2)C(F)(F)F)C(=O)c3ccccc31)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 F24 compound treatment 478610.0 -63600.0 -0.54 428010.0 -133000.0 -1.13 -1.1805 -0.9433 3187127 PK04_096120 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)c5cccs5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G01 compound treatment 386720.0 -155000.0 -1.32 550030.0 -11000.0 -0.09 -1.0013 -0.7551 3186434 PK04_096121 CN(C)CCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G02 compound treatment 498410.0 -43800.0 -0.37 524820.0 -36200.0 -0.31 -0.4807 -0.9954 3067602 PK04_096122 CC(C)N1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G03 mock treatment 542680.0 476.0 0.0 586630.0 25600.0 0.22 0.1564 0.7202 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G04 mock treatment 336160.0 -206000.0 -1.75 514400.0 -46600.0 -0.4 -1.5192 -0.8454 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G05 compound treatment 277710.0 -264000.0 -2.25 268440.0 -293000.0 -2.48 -3.3461 -0.9988 3068238 PK04_096123 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)Sc5ccc(C)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G06 compound treatment 253520.0 -289000.0 -2.46 276320.0 -285000.0 -2.42 -3.4444 -1.0 3068315 PK04_096124 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G07 compound treatment 274240.0 -268000.0 -2.28 266600.0 -294000.0 -2.5 -3.378 -0.999 3186805 PK04_096125 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G08 compound treatment 249840.0 -292000.0 -2.49 283550.0 -277000.0 -2.35 -3.4231 -0.9996 3186712 PK04_096126 COCCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G09 compound treatment 530560.0 -11600.0 -0.1 591250.0 30200.0 0.26 0.1112 0.4046 3068360 PK04_096127 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G10 compound treatment 570960.0 28800.0 0.24 558270.0 -2770.0 -0.02 0.1564 0.6364 3186431 PK04_096128 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N([C@@H]3c4ccc(CO)cc24)C5CCCCC5)c6ccc(cc6)[N+](=O)[O-])cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G11 compound treatment 321080.0 -221000.0 -1.88 298500.0 -263000.0 -2.23 -2.9049 -0.9965 3186642 PK04_096129 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2I)C3CCCCC3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G12 compound treatment 358400.0 -184000.0 -1.56 378990.0 -182000.0 -1.54 -2.1976 -1.0 3068326 PK04_096130 CCCNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G13 compound treatment 394250.0 -148000.0 -1.26 523360.0 -37700.0 -0.32 -1.116 -0.8594 3186484 PK04_096131 CCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G14 compound treatment 524110.0 -18100.0 -0.15 519520.0 -41500.0 -0.35 -0.3579 -0.9311 3068146 PK04_096132 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G15 compound treatment 520900.0 -21300.0 -0.18 620640.0 59600.0 0.51 0.2294 0.427 3068195 PK04_096133 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(C6CC6)C4=O)c7ccccc7C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G16 compound treatment 278930.0 -263000.0 -2.24 272290.0 -289000.0 -2.45 -3.3157 -0.999 3068279 PK04_096134 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G17 compound treatment 521690.0 -20500.0 -0.17 547170.0 -13900.0 -0.12 -0.2066 -0.9816 3068328 PK04_096135 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCCN5CCOCC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G18 compound treatment 248690.0 -294000.0 -2.5 253000.0 -308000.0 -2.61 -3.6133 -0.9997 3068311 PK04_096136 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G19 mock treatment 566420.0 24200.0 0.21 592480.0 31400.0 0.27 0.3343 0.9919 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G20 mock treatment 589220.0 47000.0 0.4 580360.0 19300.0 0.16 0.3987 0.9224 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G21 compound treatment 266150.0 -276000.0 -2.35 256850.0 -304000.0 -2.58 -3.4852 -0.9989 3068284 PK04_096137 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G22 compound treatment 555110.0 12900.0 0.11 526010.0 -35000.0 -0.3 -0.1325 -0.4182 3186501 PK04_096138 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G23 compound treatment 529700.0 -12500.0 -0.11 534180.0 -26900.0 -0.23 -0.2363 -0.9399 3186555 PK04_096139 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 G24 compound treatment 551370.0 9170.0 0.08 416860.0 -144000.0 -1.22 -0.8097 -0.6607 3186877 PK04_096140 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H01 compound treatment 565460.0 23300.0 0.2 458000.0 -103000.0 -0.87 -0.4781 -0.5335 3186629 PK04_096141 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H02 compound treatment 487210.0 -55000.0 -0.47 502720.0 -58300.0 -0.49 -0.6806 -0.9996 3068866 PK04_096142 OCc1ccc(cc1)c2cc[n+](Cc3cc4OCOc4cc3Br)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H03 mock treatment 481760.0 -60400.0 -0.51 599770.0 38700.0 0.33 -0.1313 -0.2151 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H04 mock treatment 591060.0 48900.0 0.42 601470.0 40400.0 0.34 0.5364 0.9954 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H05 compound treatment 570560.0 28400.0 0.24 451240.0 -110000.0 -0.93 -0.488 -0.5072 3186432 PK04_096143 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(Cc5ccccc5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H06 compound treatment 472440.0 -69800.0 -0.59 411100.0 -150000.0 -1.27 -1.319 -0.9398 3068867 PK04_096144 OCc1ccc(cc1)c2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H07 compound treatment 389120.0 -153000.0 -1.3 386250.0 -175000.0 -1.48 -1.9693 -0.9979 3187128 PK04_096145 CC(C)CN1C(=O)[C@]2(CC(=O)N(CC3C4CC5CC(C4)CC3C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H08 compound treatment 498250.0 -44000.0 -0.37 515240.0 -45800.0 -0.39 -0.5391 -0.9998 3068868 PK04_096146 COc1cc2CC[N+](=Cc2cc1O)Cc3sc4ccccc4c3Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H09 compound treatment 299840.0 -242000.0 -2.06 471260.0 -89800.0 -0.76 -1.9964 -0.9083 3186637 PK04_096147 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H10 compound treatment 453490.0 -88700.0 -0.75 513760.0 -47300.0 -0.4 -0.8172 -0.9562 3187129 PK04_096148 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(C4CC4)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H11 compound treatment 569180.0 27000.0 0.23 588820.0 27800.0 0.24 0.3289 0.9999 3187130 PK04_096149 CC1(C)OB(OC1(C)C)/C=C\CC(OC(=O)c2ccncc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H12 compound treatment 513300.0 -28900.0 -0.25 516480.0 -44600.0 -0.38 -0.4411 -0.9783 3187131 PK04_096150 C[n+]1ccc(cc1)c2ccc(CO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H13 compound treatment 524900.0 -17300.0 -0.15 602620.0 41600.0 0.35 0.1453 0.3802 3068898 PK04_096151 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)C)c2ccccc2)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H14 compound treatment 491050.0 -51200.0 -0.44 451530.0 -110000.0 -0.93 -0.9646 -0.9403 3187132 PK04_096152 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H15 compound treatment 534970.0 -7230.0 -0.06 569060.0 8020.0 0.07 0.0046 0.0503 3187133 PK04_096153 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)C)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H16 compound treatment 394800.0 -147000.0 -1.25 489630.0 -71400.0 -0.61 -1.315 -0.9443 3187134 PK04_096154 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C2)c6cccs6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H17 compound treatment 558790.0 16600.0 0.14 605050.0 44000.0 0.37 0.3638 0.9114 3068899 PK04_096155 COC(=O)c1ccc(OC)c(/C=C\CC(CCc2ccccc2)OC(=O)c3ccncc3)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H18 compound treatment 542560.0 356.0 0.0 543300.0 -17700.0 -0.15 -0.1042 -0.6927 3068900 PK04_096156 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C5CC5)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H19 mock treatment 598100.0 55900.0 0.48 524360.0 -36700.0 -0.31 0.1163 0.2046 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H20 mock treatment 588350.0 46100.0 0.39 586240.0 25200.0 0.21 0.4288 0.9592 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H21 compound treatment 265240.0 -277000.0 -2.36 199680.0 -361000.0 -3.07 -3.8336 -0.9916 3187204 PK04_096157 CC(C)(C)OC(=O)COc1cccc(c1)C(=O)CCN2CCOCC2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H22 compound treatment 541920.0 -284.0 0.0 580370.0 19300.0 0.16 0.1143 0.6966 3187205 PK04_096158 OCCCc1cc[n+](Cc2cc3OCOc3cc2Br)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H23 compound treatment 494400.0 -47800.0 -0.41 423490.0 -138000.0 -1.17 -1.1126 -0.9004 3068901 PK04_096159 COc1ccc(/C=C/C(=O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 H24 compound treatment 509600.0 -32600.0 -0.28 508760.0 -52300.0 -0.44 -0.5097 -0.9745 3187206 PK04_096160 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OC)C4CC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I01 compound treatment 222080.0 -320000.0 -2.72 243970.0 -317000.0 -2.69 -3.8275 -1.0 3186796 PK04_096161 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I02 compound treatment 561830.0 19600.0 0.17 561570.0 535.0 0.0 0.1213 0.7261 3186628 PK04_096162 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4Cl)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I03 compound treatment 500220.0 -42000.0 -0.36 420280.0 -141000.0 -1.19 -1.0968 -0.8801 3186882 PK04_096163 CN(C)CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I04 compound treatment 232710.0 -309000.0 -2.63 262280.0 -299000.0 -2.53 -3.6538 -0.9998 3186797 PK04_096164 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I05 mock treatment 502160.0 -40000.0 -0.34 383480.0 -178000.0 -1.51 -1.3059 -0.8457 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I06 mock treatment 411630.0 -131000.0 -1.11 591930.0 30900.0 0.26 -0.6002 -0.5258 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I07 compound treatment 549840.0 7640.0 0.06 527270.0 -33800.0 -0.29 -0.1566 -0.5332 3186430 PK04_096165 OCc1ccc2[C@H]3N(C4CCCCC4)C(=O)C[C@@]3(C(=O)N(C5CC5)c2c1)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I08 compound treatment 483840.0 -58400.0 -0.5 519110.0 -41900.0 -0.36 -0.6026 -0.9866 3186557 PK04_096166 CC(C)CNC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I09 compound treatment 474560.0 -67600.0 -0.58 534430.0 -26600.0 -0.23 -0.5665 -0.9165 3186558 PK04_096167 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I10 compound treatment 273810.0 -268000.0 -2.28 258650.0 -302000.0 -2.57 -3.4283 -0.9983 3068320 PK04_096168 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I11 compound treatment 557970.0 15800.0 0.13 581970.0 20900.0 0.18 0.2204 0.9904 3068364 PK04_096169 COCCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I12 compound treatment 403740.0 -138000.0 -1.18 428200.0 -133000.0 -1.13 -1.6297 -0.9998 3186489 PK04_096170 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCCN6CCOCC6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I13 compound treatment 599200.0 57000.0 0.48 501160.0 -59900.0 -0.51 -0.0163 -0.0232 3186807 PK04_096171 CC(C)CNC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I14 compound treatment 278570.0 -264000.0 -2.24 288760.0 -272000.0 -2.31 -3.2191 -0.9999 3068281 PK04_096172 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I15 compound treatment 528960.0 -13200.0 -0.11 634170.0 73100.0 0.62 0.359 0.5694 3186567 PK04_096173 CN(C)CCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I16 compound treatment 549830.0 7630.0 0.06 557880.0 -3160.0 -0.03 0.0269 0.384 3068410 PK04_096174 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCC(F)(F)F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I17 compound treatment 568640.0 26400.0 0.22 553240.0 -7800.0 -0.07 0.1123 0.4789 3186973 PK04_096175 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I18 compound treatment 557510.0 15300.0 0.13 340850.0 -220000.0 -1.87 -1.2286 -0.6562 3068148 PK04_096176 CC(C)NC(=O)[C@]1(Cc2ccccc2I)[C@@H](N(Cc3ccccc3Cl)C(=O)c4ccccc41)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I19 compound treatment 360030.0 -182000.0 -1.55 375930.0 -185000.0 -1.57 -2.2062 -1.0 3068239 PK04_096177 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCC(F)(F)F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I20 compound treatment 248820.0 -293000.0 -2.5 266310.0 -295000.0 -2.5 -3.5327 -1.0 3068268 PK04_096178 CCCNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I21 mock treatment 562920.0 20700.0 0.18 568390.0 7350.0 0.06 0.1687 0.9025 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I22 mock treatment 578120.0 35900.0 0.31 598660.0 37600.0 0.32 0.4417 0.9998 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I23 compound treatment 554960.0 12800.0 0.11 561940.0 905.0 0.01 0.0822 0.7552 3186564 PK04_096179 OCc1ccc(cc1)[C@@H]2N(C3CCCCC3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 I24 compound treatment 556010.0 13800.0 0.12 457510.0 -104000.0 -0.88 -0.5379 -0.6071 3068366 PK04_096180 CC(C)CNC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4)Sc5ccc(C)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J01 compound treatment 9320.0 -533000.0 -4.53 11200.0 -550000.0 -4.66 -6.5036 -0.9999 1230870 PK04_096181 Oc1cccc(c1)C(=O)CCN2CCOCC2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J02 compound treatment 428660.0 -114000.0 -0.97 372000.0 -189000.0 -1.6 -1.8169 -0.9706 3187207 PK04_096182 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)C3CC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J03 compound treatment 561350.0 19100.0 0.16 559860.0 -1180.0 -0.01 0.1081 0.6626 3068902 PK04_096183 COc1ccc(CC[C@H](O)c2cccc(OCC(=O)OC(C)(C)C)c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J04 compound treatment 484320.0 -57900.0 -0.49 329320.0 -232000.0 -1.97 -1.7381 -0.8577 3187208 PK04_096184 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J05 mock treatment 518880.0 -23300.0 -0.2 531320.0 -29700.0 -0.25 -0.3185 -0.993 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J06 mock treatment 586280.0 44100.0 0.37 569760.0 8720.0 0.07 0.3175 0.8306 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J07 compound treatment 469130.0 -73100.0 -0.62 441810.0 -119000.0 -1.01 -1.1547 -0.9727 3187209 PK04_096185 CCCN1C(=O)[C@@H]2Cc3c([nH]c4ccccc34)[C@H](N2C1=O)c5cccc(O)c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J08 compound treatment 518240.0 -24000.0 -0.2 493060.0 -68000.0 -0.58 -0.5519 -0.9024 3068903 PK04_096186 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J09 compound treatment 528920.0 -13300.0 -0.11 603600.0 42600.0 0.36 0.1754 0.4636 1032549 PK04_096187 CCOC(=O)C1CCCCN1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J10 compound treatment 546400.0 4200.0 0.04 622310.0 61300.0 0.52 0.3928 0.7539 3187210 PK04_096188 COc1cc2CCN(C)C(C=C)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J11 compound treatment 542140.0 -64.0 0.0 544450.0 -16600.0 -0.14 -0.0999 -0.7098 3187211 PK04_096189 CCOC(=O)[C@@H]1CCCCN1C(=O)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J12 compound treatment 577610.0 35400.0 0.3 612220.0 51200.0 0.43 0.52 0.984 3187212 PK04_096190 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4ccc(CN5CCCC5)cc4)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J13 compound treatment 600120.0 57900.0 0.49 600400.0 39400.0 0.33 0.5845 0.982 3068904 PK04_096191 [O-][N+](=O)c1cc(Br)ccc1C(=O)NCc2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J14 compound treatment 557030.0 14800.0 0.13 576850.0 15800.0 0.13 0.184 0.9995 3068905 PK04_096192 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C=C)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J15 compound treatment 601280.0 59100.0 0.5 613700.0 52700.0 0.45 0.6713 0.9983 3187213 PK04_096193 CC(=O)Nc1cc(Br)ccc1C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J16 compound treatment 360000.0 -182000.0 -1.55 560350.0 -685.0 -0.01 -1.1002 -0.7098 3187214 PK04_096194 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(c5cccs5)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J17 compound treatment 584340.0 42100.0 0.36 568090.0 7050.0 0.06 0.2958 0.8139 3068906 PK04_096195 CC(=O)Nc1cc(Br)ccc1C(=O)NCc2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J18 compound treatment 571580.0 29400.0 0.25 602400.0 41400.0 0.35 0.4248 0.9862 3187215 PK04_096196 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5cccs5)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J19 compound treatment 582180.0 40000.0 0.34 390190.0 -171000.0 -1.45 -0.7843 -0.5269 3068907 PK04_096197 Brc1ccc2c(=O)oc(nc2c1)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J20 compound treatment 401320.0 -141000.0 -1.2 388130.0 -173000.0 -1.47 -1.8846 -0.995 3187216 PK04_096198 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4ccc(CN5CCCC5)cc4)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J21 mock treatment 597890.0 55700.0 0.47 605540.0 44500.0 0.38 0.6019 0.9937 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J22 mock treatment 579420.0 37200.0 0.32 616840.0 55800.0 0.47 0.5586 0.9809 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J23 compound treatment 554290.0 12100.0 0.1 576530.0 15500.0 0.13 0.1656 0.9926 3068908 PK04_096199 Nc1cc(Br)ccc1C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 J24 compound treatment 483460.0 -58700.0 -0.5 440400.0 -121000.0 -1.02 -1.077 -0.9457 3068910 PK04_096200 Oc1ccc2cc[n+](Cc3ccc(o3)[N+](=O)[O-])cc2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K01 compound treatment 439360.0 -103000.0 -0.87 561680.0 645.0 0.01 -0.6148 -0.7027 3068198 PK04_096201 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(Cc6ccccc6)C4=O)c7ccccc7C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K02 compound treatment 500270.0 -41900.0 -0.36 479760.0 -81300.0 -0.69 -0.7398 -0.953 3186870 PK04_096202 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K03 compound treatment 466910.0 -75300.0 -0.64 478810.0 -82200.0 -0.7 -0.9461 -0.9991 3068155 PK04_096203 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCC(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K04 compound treatment 562830.0 20600.0 0.18 602690.0 41700.0 0.35 0.3739 0.9478 3186875 PK04_096204 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCC(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K05 compound treatment 366510.0 -176000.0 -1.49 402660.0 -158000.0 -1.34 -2.0069 -0.9986 3068359 PK04_096205 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NC4CC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K06 compound treatment 380870.0 -161000.0 -1.37 423130.0 -138000.0 -1.17 -1.7977 -0.9968 3186626 PK04_096206 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CC(F)(F)F)C4=O)c6ccccc6C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K07 mock treatment 579250.0 37000.0 0.32 343680.0 -217000.0 -1.84 -1.0809 -0.5779 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K08 mock treatment 618350.0 76100.0 0.65 575600.0 14600.0 0.12 0.5454 0.8271 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K09 compound treatment 441920.0 -100000.0 -0.85 489190.0 -71800.0 -0.61 -1.0342 -0.9864 3186869 PK04_096207 COc1ccc(CCNC(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)Sc5ccc(C)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K10 compound treatment 456260.0 -85900.0 -0.73 554560.0 -6480.0 -0.05 -0.5558 -0.7581 3068235 PK04_096208 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K11 compound treatment 526790.0 -15400.0 -0.13 612800.0 51800.0 0.44 0.2178 0.4752 3186487 PK04_096209 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(Cc7ccccc7)c2c1)c8ccc(cc8)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K12 compound treatment 595060.0 52900.0 0.45 503110.0 -57900.0 -0.49 -0.0295 -0.0443 3068411 PK04_096210 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K13 compound treatment 473140.0 -69100.0 -0.59 476360.0 -84700.0 -0.72 -0.9234 -0.995 3068329 PK04_096211 CC(C)NC(=O)[C@]1(CC(=O)N([C@@H]1c2ccc(CO)cc2)C3CCCCC3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K14 compound treatment 612850.0 70600.0 0.6 629470.0 68400.0 0.58 0.8355 0.9998 3067608 PK04_096212 COCCCN1C(=O)[C@]2(CC(=O)N([C@@H]2c3ccc(CO)cc13)C4CCCCC4)c5ccc(cc5)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K15 mock treatment 650090.0 108000.0 0.92 644980.0 83900.0 0.71 1.1525 0.9921 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K16 mock treatment 629140.0 86900.0 0.74 547120.0 -13900.0 -0.12 0.4395 0.5868 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K17 compound treatment 538660.0 -3540.0 -0.03 616320.0 55300.0 0.47 0.3103 0.6603 3186979 PK04_096213 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K18 compound treatment 620830.0 78600.0 0.67 657230.0 96200.0 0.82 1.05 0.9951 3186636 PK04_096214 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K19 compound treatment 267570.0 -275000.0 -2.34 255890.0 -305000.0 -2.59 -3.4824 -0.9987 3186793 PK04_096215 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K20 compound treatment 621250.0 79000.0 0.67 570660.0 9620.0 0.08 0.5332 0.7872 3186637 PK04_096216 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K21 compound treatment 490240.0 -52000.0 -0.44 492480.0 -68600.0 -0.58 -0.7238 -0.9908 3067613 PK04_096217 COc1ccc(CCN2C(=O)[C@]3(CC(=O)N(CC4(CC5CC6CC(C5)C4)C6)[C@@H]3c7ccc(CO)cc27)c8ccc(cc8)[N+](=O)[O-])cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K22 compound treatment 548020.0 5820.0 0.05 601700.0 40700.0 0.34 0.2789 0.8003 3186873 PK04_096218 CCCNC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K23 mock treatment 569280.0 27100.0 0.23 585600.0 24600.0 0.21 0.3102 0.9987 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 K24 mock treatment 587200.0 45000.0 0.38 529060.0 -32000.0 -0.27 0.0789 0.1681 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L01 compound treatment 544830.0 2630.0 0.02 493640.0 -67400.0 -0.57 -0.3885 -0.679 3068940 PK04_096219 Cc1nc2cc(Br)ccc2c(=O)o1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L02 compound treatment 427360.0 -115000.0 -0.98 410880.0 -150000.0 -1.27 -1.5915 -0.9914 3187217 PK04_096220 COc1cc2CCN(Cc3cc4OCOc4cc3Br)C(c5ccc(CN6CCCC6)cc5)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L03 compound treatment 307200.0 -235000.0 -2.0 551070.0 -9970.0 -0.08 -1.4735 -0.7363 3068941 PK04_096221 CC(C)c1nc2cc(Br)ccc2c(=O)o1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L04 compound treatment 425310.0 -117000.0 -0.99 462960.0 -98100.0 -0.83 -1.2915 -0.9961 3068942 PK04_096222 COc1cc2CCN(Cc3sc4ccccc4c3Cl)C(C)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L05 compound treatment 525960.0 -16200.0 -0.14 554190.0 -6850.0 -0.06 -0.1388 -0.9258 3187218 PK04_096223 Cc1nc2cc(Br)ccc2c(=O)n1Cc3cccc(O)c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L06 compound treatment 566900.0 24700.0 0.21 585170.0 24100.0 0.2 0.2933 0.9999 3068943 PK04_096224 COc1cc2CCN(C)C(c3cccs3)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L07 mock treatment 526580.0 -15600.0 -0.13 635490.0 74500.0 0.63 0.3526 0.5463 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L08 mock treatment 542890.0 686.0 0.01 574810.0 13800.0 0.12 0.0868 0.7415 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L09 compound treatment 599810.0 57600.0 0.49 600220.0 39200.0 0.33 0.5816 0.9821 3187219 PK04_096225 Oc1cccc(CNC(=O)c2ccc(Br)cc2NC(=O)c3ccccc3)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L10 compound treatment 537510.0 -4690.0 -0.04 526560.0 -34500.0 -0.29 -0.235 -0.7963 3187220 PK04_096226 COC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OC)c4ccc(CO)cc4)C5CC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L11 compound treatment 524490.0 -17700.0 -0.15 415750.0 -145000.0 -1.23 -0.978 -0.7877 3068944 PK04_096227 Oc1cccc(Cn2c(nc3cc(Br)ccc3c2=O)c4ccccc4)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L12 compound treatment 425380.0 -117000.0 -0.99 557440.0 -3600.0 -0.03 -0.7243 -0.7285 3187221 PK04_096228 CN1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L13 compound treatment 418660.0 -124000.0 -1.05 529300.0 -31700.0 -0.27 -0.9335 -0.8604 1980253 PK04_096229 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2)/C#N)c(=O)n(c3ccccc3)n1C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L14 compound treatment 454640.0 -87600.0 -0.74 459100.0 -102000.0 -0.86 -1.1382 -0.9972 3068945 PK04_096230 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L15 mock treatment 462890.0 -79300.0 -0.67 593560.0 32500.0 0.28 -0.282 -0.3869 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L16 mock treatment 565870.0 23700.0 0.2 577840.0 16800.0 0.14 0.2432 0.9857 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L17 compound treatment 182140.0 -360000.0 -3.06 202150.0 -359000.0 -3.04 -4.3186 -1.0 3187222 PK04_096231 Cc1c(NC(=O)/C(=C/C=C/c2ccccc2[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L18 compound treatment 420120.0 -122000.0 -1.04 506930.0 -54100.0 -0.46 -1.0589 -0.9326 3187223 PK04_096232 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6cccs6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L19 compound treatment 454520.0 -87700.0 -0.75 296870.0 -264000.0 -2.24 -2.112 -0.8942 3068946 PK04_096233 Cc1c(NC(=O)/C(=C/C=C/c2ccc(cc2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L20 compound treatment 519900.0 -22300.0 -0.19 431280.0 -130000.0 -1.1 -0.9125 -0.817 3187224 PK04_096234 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5cccs5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L21 compound treatment 479010.0 -63200.0 -0.54 453440.0 -108000.0 -0.91 -1.0255 -0.9681 3068947 PK04_096235 CN(C)c1ccc(/C=C/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L22 compound treatment 527440.0 -14800.0 -0.13 521790.0 -39200.0 -0.33 -0.3242 -0.9112 3187225 PK04_096236 COc1cc2CCN(C)C(C3CC3)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L23 mock treatment 552920.0 10700.0 0.09 569470.0 8430.0 0.07 0.1151 0.9928 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 L24 mock treatment 539540.0 -2660.0 -0.02 536330.0 -24700.0 -0.21 -0.1642 -0.779 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M01 compound treatment 526180.0 -16000.0 -0.14 308230.0 -253000.0 -2.14 -1.6128 -0.7505 3186502 PK04_096237 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M02 compound treatment 518080.0 -24100.0 -0.21 544060.0 -17000.0 -0.14 -0.2469 -0.985 3186497 PK04_096238 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@@](Cc4ccccc4I)(C(=O)NC(C)C)c5ccccc5C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M03 compound treatment 534270.0 -7930.0 -0.07 535090.0 -25900.0 -0.22 -0.2034 -0.8834 3068404 PK04_096239 COCCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M04 compound treatment 211070.0 -331000.0 -2.82 272960.0 -288000.0 -2.44 -3.7199 -0.9975 3186643 PK04_096240 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NC5CC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M05 compound treatment 255800.0 -286000.0 -2.44 238620.0 -322000.0 -2.73 -3.6568 -0.9983 3186723 PK04_096241 CCCNC(=O)[C@]1(CC(=O)N(Cc2ccccc2Cl)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M06 compound treatment 536670.0 -5530.0 -0.05 527330.0 -33700.0 -0.29 -0.2355 -0.8126 3186868 PK04_096242 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3)C4CCCCC4)C(=O)NC5CC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M07 compound treatment 243010.0 -299000.0 -2.55 270500.0 -291000.0 -2.46 -3.5425 -0.9999 3186798 PK04_096243 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M08 compound treatment 249500.0 -293000.0 -2.49 252080.0 -309000.0 -2.62 -3.614 -0.9997 3186799 PK04_096244 CN(C)CCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3I)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M09 mock treatment 354520.0 -188000.0 -1.6 481850.0 -79200.0 -0.67 -1.604 -0.926 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M10 mock treatment 637600.0 95400.0 0.81 618690.0 57700.0 0.49 0.9197 0.9706 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M11 compound treatment 548330.0 6130.0 0.05 439310.0 -122000.0 -1.03 -0.6933 -0.6706 3186496 PK04_096245 COc1ccc(CCNC(=O)[C@]2(Cc3ccccc3I)[C@@H](N(Cc4ccccc4OC)C(=O)c5ccccc52)c6ccc(CO)cc6)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M12 compound treatment 584030.0 41800.0 0.36 575200.0 14200.0 0.12 0.3366 0.8962 3068379 PK04_096246 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M13 mock treatment 464290.0 -77900.0 -0.66 564490.0 3450.0 0.03 -0.448 -0.6752 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M14 mock treatment 619080.0 76900.0 0.65 595090.0 34100.0 0.29 0.6667 0.9325 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M15 compound treatment 595870.0 53700.0 0.46 529000.0 -32000.0 -0.27 0.1307 0.246 3186488 PK04_096247 CC(C)N1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M16 compound treatment 462460.0 -79700.0 -0.68 586730.0 25700.0 0.22 -0.3256 -0.4569 3186886 PK04_096248 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M17 compound treatment 581810.0 39600.0 0.34 633540.0 72500.0 0.62 0.6732 0.9599 3068154 PK04_096249 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3)C(=O)c4ccccc4[C@]2(Cc5ccccc5I)C(=O)NCc6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M18 compound treatment 566080.0 23900.0 0.2 526030.0 -35000.0 -0.3 -0.0663 -0.1844 3068369 PK04_096250 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCC(F)(F)F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M19 compound treatment 237950.0 -304000.0 -2.59 262310.0 -299000.0 -2.53 -3.6221 -0.9999 3186727 PK04_096251 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M20 compound treatment 540910.0 -1290.0 -0.01 535620.0 -25400.0 -0.22 -0.1602 -0.7422 3186984 PK04_096252 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4)Sc5ccc(C)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M21 compound treatment 359270.0 -183000.0 -1.56 456810.0 -104000.0 -0.88 -1.7256 -0.9641 3068372 PK04_096253 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4)C(=O)NC5CC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M22 compound treatment 232850.0 -309000.0 -2.63 236600.0 -324000.0 -2.75 -3.807 -0.9998 3186721 PK04_096254 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5I)C(=O)NCC(F)(F)F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M23 compound treatment 249350.0 -293000.0 -2.49 238350.0 -323000.0 -2.74 -3.6972 -0.9989 3068316 PK04_096255 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCc5ccccc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 M24 compound treatment 248560.0 -294000.0 -2.5 227260.0 -334000.0 -2.83 -3.7685 -0.9981 3068283 PK04_096256 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N01 compound treatment 564200.0 22000.0 0.19 550800.0 -10200.0 -0.09 0.0709 0.3438 1694663 PK04_096257 Cc1c(NC(=O)CC#N)c(=O)n(c2ccccc2)n1C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N02 compound treatment 479550.0 -62700.0 -0.53 366570.0 -194000.0 -1.65 -1.5433 -0.8903 3187226 PK04_096258 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C)C=C(CCCO)C=C1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N03 compound treatment 508560.0 -33600.0 -0.29 484830.0 -76200.0 -0.65 -0.6595 -0.9328 3068949 PK04_096259 Cc1ccccc1/C=C/C=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N04 compound treatment 359320.0 -183000.0 -1.56 541650.0 -19400.0 -0.16 -1.2164 -0.7775 3187227 PK04_096260 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)c2ccc(CN3CCCC3)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N05 compound treatment 564400.0 22200.0 0.19 564000.0 2960.0 0.03 0.1513 0.7943 3068950 PK04_096261 CCOc1ccc(cc1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N06 compound treatment 502720.0 -39500.0 -0.34 467700.0 -93300.0 -0.79 -0.7974 -0.9271 3187228 PK04_096262 Oc1ccc2cc[n+](Cc3cccc(OC(F)(F)F)c3)cc2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N07 compound treatment 484510.0 -57700.0 -0.49 594930.0 33900.0 0.29 -0.1438 -0.2527 3068951 PK04_096263 [O-][N+](=O)c1cccc(c1)C2SCC(=O)N2c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N08 compound treatment 536970.0 -5230.0 -0.04 471580.0 -89500.0 -0.76 -0.5681 -0.7473 3187299 PK04_096264 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4cccs4)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N09 mock treatment 450720.0 -91500.0 -0.78 627480.0 66400.0 0.56 -0.1518 -0.1579 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N10 mock treatment 604240.0 62000.0 0.53 586210.0 25200.0 0.21 0.5242 0.9207 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N11 compound treatment 393370.0 -149000.0 -1.27 530890.0 -30100.0 -0.26 -1.0761 -0.8331 3068985 PK04_096265 Cc1cc(C)cc(c1)N2C(SCC2=O)c3cccc(c3)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N12 compound treatment 549130.0 6930.0 0.06 457240.0 -104000.0 -0.88 -0.5809 -0.6583 3187300 PK04_096266 COc1cc2CCN(C)C(c3ccc(CN4CCCC4)cc3)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N13 mock treatment 585050.0 42800.0 0.36 585540.0 24500.0 0.21 0.4047 0.9645 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N14 mock treatment 625330.0 83100.0 0.71 600710.0 39700.0 0.34 0.738 0.9424 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N15 compound treatment 464560.0 -77600.0 -0.66 406160.0 -155000.0 -1.31 -1.396 -0.9494 3068986 PK04_096267 COc1ccc(/C=C/C=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N16 compound treatment 496110.0 -46100.0 -0.39 484960.0 -76100.0 -0.65 -0.7336 -0.9715 3187301 PK04_096268 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N17 compound treatment 541800.0 -404.0 0.0 524510.0 -36500.0 -0.31 -0.2215 -0.7149 3068987 PK04_096269 Cc1cccc(/C=C/C=O)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N18 compound treatment 495850.0 -46400.0 -0.39 543250.0 -17800.0 -0.15 -0.3855 -0.9131 3068988 PK04_096270 OCCCc1cc[n+](Cc2sc3ccccc3c2Cl)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N19 compound treatment 218930.0 -323000.0 -2.75 554050.0 -6990.0 -0.06 -1.9866 -0.7222 3068989 PK04_096271 Cc1ccc(/C=C/C=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N20 compound treatment 341440.0 -201000.0 -1.71 364910.0 -196000.0 -1.66 -2.3841 -0.9999 3187302 PK04_096272 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N21 compound treatment 417000.0 -125000.0 -1.07 350190.0 -211000.0 -1.79 -2.0179 -0.9693 3068990 PK04_096273 COc1cccc(/C=C/C=O)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N22 compound treatment 504200.0 -38000.0 -0.32 429760.0 -131000.0 -1.11 -1.016 -0.8762 3068991 PK04_096274 Oc1ccc2cc[n+](Cc3cc4OCOc4cc3Br)cc2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N23 compound treatment 506080.0 -36100.0 -0.31 485540.0 -75500.0 -0.64 -0.6701 -0.9434 3187303 PK04_096275 Clc1ccccc1/C=C/C=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 N24 compound treatment 536270.0 -5930.0 -0.05 496370.0 -64700.0 -0.55 -0.4236 -0.7689 3187304 PK04_096276 CN/1C(C=C(C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4ccc(CO)cc4)C5CC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O01 compound treatment 443650.0 -98600.0 -0.84 450030.0 -111000.0 -0.94 -1.2587 -0.9983 3186631 PK04_096277 CC(C)CN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(Cc4ccccc4C(F)(F)F)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O02 compound treatment 337470.0 -205000.0 -1.74 482100.0 -78900.0 -0.67 -1.7051 -0.9137 3067615 PK04_096278 OCc1ccc2[C@H]3N(CC4(CC5CC6CC(C5)C4)C6)C(=O)C[C@@]3(C(=O)N(CC(F)(F)F)c2c1)c7ccc(cc7)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O03 compound treatment 202280.0 -340000.0 -2.89 113300.0 -448000.0 -3.8 -4.7304 -0.991 3186715 PK04_096279 CC(C)N1[C@H](c2ccc(CO)cc2I)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCCCN(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O04 compound treatment 508000.0 -34200.0 -0.29 362650.0 -198000.0 -1.68 -1.3957 -0.8172 3068363 PK04_096280 CC(C)NC(=O)[C@]1(CC(=O)N(C(C)C)[C@@H]1c2ccc(CO)cc2)Sc3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O05 compound treatment 233400.0 -309000.0 -2.63 220840.0 -340000.0 -2.89 -3.8982 -0.9989 3068310 PK04_096281 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3C(F)(F)F)[C@@H]2c4ccc(CO)cc4I)C(=O)NCC(F)(F)F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O06 compound treatment 546830.0 4630.0 0.04 501970.0 -59100.0 -0.5 -0.3265 -0.6496 3068196 PK04_096282 COc1ccccc1CN2[C@@H](c3ccc(CO)cc3)[C@]4(Cc5ccccc5N(CCN6CCOCC6)C4=O)c7ccccc7C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O07 compound treatment 220390.0 -322000.0 -2.74 229170.0 -332000.0 -2.82 -3.9265 -0.9999 3068277 PK04_096283 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)Sc5ccc(C)cc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O08 compound treatment 215170.0 -327000.0 -2.78 217810.0 -343000.0 -2.91 -4.026 -0.9997 3186720 PK04_096284 CC(C)NC(=O)[C@]1(CC(=O)N(C2Cc3ccccc3C2)[C@@H]1c4ccc(CO)cc4I)Sc5ccc(C)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O09 compound treatment 504090.0 -38100.0 -0.32 489070.0 -72000.0 -0.61 -0.6609 -0.9562 3186632 PK04_096285 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3C(F)(F)F)C(=O)c4ccccc4[C@]52Cc6ccccc6N(CCN7CCOCC7)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O10 compound treatment 493500.0 -48700.0 -0.41 517240.0 -43800.0 -0.37 -0.5557 -0.9985 3068157 PK04_096286 COc1ccc(CCN2C(=O)[C@]3(Cc4ccccc24)[C@@H](N(C5CCCCC5)C(=O)c6ccccc63)c7ccc(CO)cc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O11 mock treatment 528800.0 -13400.0 -0.11 541410.0 -19600.0 -0.17 -0.1983 -0.983 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O12 mock treatment 370970.0 -171000.0 -1.46 521150.0 -39900.0 -0.34 -1.2693 -0.8487 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O13 compound treatment 454400.0 -87800.0 -0.75 535230.0 -25800.0 -0.22 -0.683 -0.8774 3186874 PK04_096287 CC(C)N1[C@H](c2ccc(CO)cc2)[C@@](CC1=O)(Sc3ccc(C)cc3)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O14 compound treatment 505280.0 -36900.0 -0.31 476000.0 -85000.0 -0.72 -0.7322 -0.9306 3068138 PK04_096288 COCCCN1C(=O)[C@]2(CC(=O)N(CC3(CC4CC5CC(C4)C3)C5)[C@@H]2c6ccc(CO)cc16)c7ccc(cc7)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O15 compound treatment 525380.0 -16800.0 -0.14 537630.0 -23400.0 -0.2 -0.2416 -0.9871 3186972 PK04_096289 CC(C)CNC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O16 compound treatment 491930.0 -50300.0 -0.43 488060.0 -73000.0 -0.62 -0.7401 -0.9837 3186981 PK04_096290 COCCCNC(=O)[C@]1(CC(=O)N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O17 compound treatment 213830.0 -328000.0 -2.79 229070.0 -332000.0 -2.82 -3.9665 -1.0 3186709 PK04_096291 Cc1ccc(S[C@@]2(CC(=O)N([C@@H]2c3ccc(CO)cc3I)C4CCCCC4)C(=O)NCc5ccccc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O18 compound treatment 231400.0 -311000.0 -2.64 231960.0 -329000.0 -2.79 -3.8435 -0.9996 3186725 PK04_096292 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3Cl)[C@@H]2c4ccc(CO)cc4I)C(=O)NCCN5CCOCC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O19 compound treatment 240710.0 -301000.0 -2.56 231290.0 -330000.0 -2.8 -3.7915 -0.9991 3068321 PK04_096293 Cc1ccc(S[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccc(CO)cc4I)C(=O)NC5CC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O20 compound treatment 513650.0 -28600.0 -0.24 485440.0 -75600.0 -0.64 -0.6252 -0.9117 3068192 PK04_096294 COCCCN1C(=O)[C@]2(Cc3ccccc13)[C@@H](N(C4CCCCC4)C(=O)c5ccccc52)c6ccc(CO)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O21 compound treatment 428370.0 -114000.0 -0.97 376960.0 -184000.0 -1.56 -1.7889 -0.9736 3068201 PK04_096295 OCc1ccc(cc1)[C@@H]2N(Cc3ccccc3Cl)C(=O)c4ccccc4[C@]52Cc6ccccc6N(C7CC7)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O22 compound treatment 496880.0 -45300.0 -0.39 429470.0 -132000.0 -1.12 -1.0618 -0.8993 3068381 PK04_096296 CC(C)NC(=O)[C@]1(CC(=O)N(Cc2ccccc2C(F)(F)F)[C@@H]1c3ccc(CO)cc3)Sc4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O23 compound treatment 356490.0 -186000.0 -1.58 413360.0 -148000.0 -1.25 -2.003 -0.9934 3186880 PK04_096297 Cc1ccc(S[C@@]2(CC(=O)N(C3Cc4ccccc4C3)[C@@H]2c5ccc(CO)cc5)C(=O)NCc6ccccc6)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 O24 compound treatment 439780.0 -102000.0 -0.87 369680.0 -191000.0 -1.62 -1.7639 -0.9575 3186977 PK04_096298 Cc1ccc(S[C@@]2(CC(=O)N(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)[C@@H]2c4ccc(CO)cc4)C(=O)NCCN5CCOCC5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P01 compound treatment 340270.0 -202000.0 -1.72 322820.0 -238000.0 -2.02 -2.6436 -0.9967 3068992 PK04_096299 Cc1c(NC(=O)/C(=C/c2cccc(c2)[N+](=O)[O-])/C#N)c(=O)n(c3ccccc3)n1C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P02 compound treatment 379870.0 -162000.0 -1.38 370260.0 -191000.0 -1.62 -2.1208 -0.9969 3187305 PK04_096300 COC(=O)C1=CN(C)C(C=C(CCCO)C=C1C(=O)OC)C2CC2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P03 compound treatment 363650.0 -179000.0 -1.52 345190.0 -216000.0 -1.83 -2.3688 -0.9957 3187306 PK04_096301 COc1cccc(/C=C(\C#N)/C(=O)Nc2c(C)n(C)n(c3ccccc3)c2=O)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P04 compound treatment 334920.0 -207000.0 -1.76 381390.0 -180000.0 -1.52 -2.3245 -0.9974 3068993 PK04_096302 COc1cc2CC[N+](=Cc2cc1O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P05 compound treatment 387540.0 -155000.0 -1.32 382150.0 -179000.0 -1.52 -2.0034 -0.9975 3068994 PK04_096303 Cc1c(NC(=O)/C(=C/c2ccccc2Cl)/C#N)c(=O)n(c3ccccc3)n1C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P06 compound treatment 336670.0 -206000.0 -1.75 368320.0 -193000.0 -1.63 -2.3923 -0.9994 3187307 PK04_096304 COc1cc2CCN(Cc3cccc(OC(F)(F)F)c3)C(c4cccs4)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P07 compound treatment 364000.0 -178000.0 -1.52 383770.0 -177000.0 -1.5 -2.1353 -1.0 3187308 PK04_096305 Cc1c(NC(=O)/C(=C/c2ccc(Cl)cc2)/C#N)c(=O)n(c3ccccc3)n1C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P08 compound treatment 344530.0 -198000.0 -1.68 353510.0 -208000.0 -1.76 -2.4339 -0.9997 3068995 PK04_096306 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3CCCO)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P09 compound treatment 276000.0 -266000.0 -2.26 289020.0 -272000.0 -2.31 -3.233 -1.0 1972122 PK04_096307 Cc1cc(C)cc(c1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)CC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P10 compound treatment 234350.0 -308000.0 -2.62 326320.0 -235000.0 -1.99 -3.2598 -0.9908 3187309 PK04_096308 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)C4CC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P11 mock treatment 255370.0 -287000.0 -2.44 314680.0 -246000.0 -2.09 -3.2032 -0.997 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P12 mock treatment 331010.0 -211000.0 -1.8 293440.0 -268000.0 -2.27 -2.8755 -0.9933 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P13 compound treatment 148550.0 -394000.0 -3.35 144120.0 -417000.0 -3.54 -4.8688 -0.9996 3068996 PK04_096309 Clc1ccc(/C=C/C=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P14 compound treatment 339860.0 -202000.0 -1.72 369320.0 -192000.0 -1.63 -2.3672 -0.9996 3187310 PK04_096310 COc1cc2CC[N+](=Cc2cc1O)Cc3cccc(OC(F)(F)F)c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P15 compound treatment 265220.0 -277000.0 -2.36 202290.0 -359000.0 -3.04 -3.818 -0.992 3068997 PK04_096311 O=C/C=C/c1ccc2OCOc2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P16 compound treatment 247250.0 -295000.0 -2.51 281450.0 -280000.0 -2.37 -3.4513 -0.9996 3187311 PK04_096312 COC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OC)c3ccc(CN4CCCC4)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P17 compound treatment 10120.0 -532000.0 -4.53 25180.0 -536000.0 -4.55 -6.4149 -1.0 3068998 PK04_096313 O=C/C=C/c1ccc(cc1)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P18 compound treatment 153290.0 -389000.0 -3.31 202400.0 -359000.0 -3.04 -4.4907 -0.9991 3187312 PK04_096314 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P19 compound treatment 241180.0 -301000.0 -2.56 192050.0 -369000.0 -3.13 -4.0241 -0.995 3187313 PK04_096315 O=C/C=C/c1ccc(\C=C\c2ccccc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P20 compound treatment 308040.0 -234000.0 -1.99 269920.0 -291000.0 -2.47 -3.1548 -0.9943 3187314 PK04_096316 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(c4cccs4)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P21 compound treatment 316030.0 -226000.0 -1.92 316550.0 -244000.0 -2.07 -2.827 -0.9993 3069028 PK04_096317 [O-][N+](=O)c1cccc(c1)C2N(C(=O)CS2(=O)=O)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P22 compound treatment 204430.0 -338000.0 -2.87 203840.0 -357000.0 -3.03 -4.1744 -0.9996 3187315 PK04_096318 COC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OC)c4ccc(CN5CCCC5)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P23 compound treatment 155950.0 -386000.0 -3.29 162770.0 -398000.0 -3.38 -4.7124 -0.9999 3069029 PK04_096319 CCOc1ccc(cc1)N2C(c3cccc(c3)[N+](=O)[O-])S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2096 P24 compound treatment 277880.0 -264000.0 -2.25 278420.0 -283000.0 -2.4 -3.2852 -0.9995 3187316 PK04_096320 COC(=O)C1=CN(C)C(C=C(C=C1C(=O)OC)c2ccc(CO)cc2)C3CC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A01 compound treatment 495260.0 -27300.0 -0.23 347360.0 -163000.0 -1.38 -1.1398 -0.8148 2141518 PK04_097001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A02 compound treatment 436650.0 -85900.0 -0.73 316540.0 -193000.0 -1.64 -1.6773 -0.9337 2141905 PK04_097002 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A03 compound treatment 306790.0 -216000.0 -1.84 282090.0 -228000.0 -1.93 -2.6651 -0.9997 2141091 PK04_097003 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A04 compound treatment 500650.0 -21900.0 -0.19 429700.0 -80300.0 -0.68 -0.6135 -0.8688 2141692 PK04_097004 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A05 compound treatment 433700.0 -88900.0 -0.76 492480.0 -17500.0 -0.15 -0.6397 -0.8302 2141533 PK04_097005 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A06 compound treatment 85870.0 -437000.0 -3.72 91040.0 -419000.0 -3.55 -5.14 -0.9998 2141714 PK04_097006 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A07 compound treatment 477090.0 -45500.0 -0.39 472800.0 -37200.0 -0.32 -0.4967 -0.9949 2141463 PK04_097007 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A08 compound treatment 499360.0 -23200.0 -0.2 458020.0 -52000.0 -0.44 -0.4514 -0.9344 2141076 PK04_097008 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A09 compound treatment 479200.0 -43400.0 -0.37 353280.0 -157000.0 -1.33 -1.2009 -0.8705 2141109 PK04_097009 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A10 compound treatment 327230.0 -195000.0 -1.66 281640.0 -228000.0 -1.94 -2.5448 -0.9971 2141546 PK04_097010 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A11 compound treatment 449250.0 -73300.0 -0.62 507390.0 -2600.0 -0.02 -0.4567 -0.7317 2141079 PK04_097011 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A12 compound treatment 354780.0 -168000.0 -1.43 339050.0 -171000.0 -1.45 -2.0347 -1.0 2141141 PK04_097012 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A13 mock treatment 324560.0 -198000.0 -1.68 371630.0 -138000.0 -1.17 -2.0211 -0.9844 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A14 mock treatment 453600.0 -69000.0 -0.59 417920.0 -92100.0 -0.78 -0.9672 -0.9901 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A15 compound treatment 349800.0 -173000.0 -1.47 372970.0 -137000.0 -1.16 -1.8612 -0.9932 2141882 PK04_097013 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A16 compound treatment 484160.0 -38400.0 -0.33 440050.0 -69900.0 -0.59 -0.6506 -0.9605 2141936 PK04_097014 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A17 compound treatment 351470.0 -171000.0 -1.46 272180.0 -238000.0 -2.02 -2.4558 -0.9872 2141372 PK04_097015 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A18 compound treatment 495460.0 -27100.0 -0.23 506500.0 -3490.0 -0.03 -0.1841 -0.7914 2141092 PK04_097016 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A19 compound treatment 470240.0 -52300.0 -0.45 419160.0 -90800.0 -0.77 -0.8597 -0.966 2141344 PK04_097017 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A20 compound treatment 499080.0 -23500.0 -0.2 396690.0 -113000.0 -0.96 -0.821 -0.8363 2141115 PK04_097018 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A21 compound treatment 394510.0 -128000.0 -1.09 340060.0 -170000.0 -1.44 -1.7897 -0.9905 2141570 PK04_097019 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A22 compound treatment 405810.0 -117000.0 -0.99 403230.0 -107000.0 -0.91 -1.3428 -0.9989 2141549 PK04_097020 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A23 compound treatment 449190.0 -73400.0 -0.62 421720.0 -88300.0 -0.75 -0.9709 -0.9959 2141876 PK04_097021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 A24 compound treatment 446080.0 -76500.0 -0.65 454080.0 -55900.0 -0.47 -0.7955 -0.9879 2141753 PK04_097022 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B01 compound treatment 479540.0 -43000.0 -0.37 472990.0 -37000.0 -0.31 -0.4808 -0.9971 2141940 PK04_097023 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B02 compound treatment 403750.0 -119000.0 -1.01 451270.0 -58700.0 -0.5 -1.067 -0.9468 2142685 PK04_097024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B03 compound treatment 478720.0 -43900.0 -0.37 462880.0 -47100.0 -0.4 -0.5464 -0.9994 2141335 PK04_097025 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B04 compound treatment 492960.0 -29600.0 -0.25 439270.0 -70700.0 -0.6 -0.6024 -0.9258 2143933 PK04_097026 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B05 compound treatment 494110.0 -28500.0 -0.24 475920.0 -34100.0 -0.29 -0.3756 -0.9961 2141445 PK04_097027 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B06 compound treatment 428350.0 -94200.0 -0.8 412870.0 -97100.0 -0.82 -1.1494 -0.9999 2144925 PK04_097028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B07 compound treatment 276480.0 -246000.0 -2.09 281560.0 -228000.0 -1.94 -2.8506 -0.9993 2141881 PK04_097029 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B08 compound treatment 422330.0 -100000.0 -0.85 501640.0 -8350.0 -0.07 -0.6531 -0.7632 2144289 PK04_097030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B09 compound treatment 359720.0 -163000.0 -1.39 344410.0 -166000.0 -1.4 -1.9729 -1.0 2141150 PK04_097031 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B10 compound treatment 284210.0 -238000.0 -2.03 432910.0 -77100.0 -0.65 -1.8963 -0.89 2144633 PK04_097032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B11 compound treatment 469310.0 -53300.0 -0.45 389250.0 -121000.0 -1.02 -1.0447 -0.9328 2141161 PK04_097033 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B12 compound treatment 544920.0 22300.0 0.19 523780.0 13800.0 0.12 0.2171 0.9728 2144765 PK04_097034 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B13 mock treatment 556810.0 34200.0 0.29 480220.0 -29800.0 -0.25 0.0273 0.0709 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B14 mock treatment 515360.0 -7220.0 -0.06 525310.0 15300.0 0.13 0.0485 0.3372 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B15 compound treatment 545650.0 23100.0 0.2 547040.0 37000.0 0.31 0.361 0.9743 2141135 PK04_097035 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B16 compound treatment 537510.0 14900.0 0.13 460330.0 -49700.0 -0.42 -0.2081 -0.4729 2144753 PK04_097036 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B17 compound treatment 483230.0 -39300.0 -0.33 491730.0 -18300.0 -0.15 -0.3462 -0.9387 2141225 PK04_097037 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B18 compound treatment 301050.0 -222000.0 -1.88 245920.0 -264000.0 -2.24 -2.9166 -0.9963 2144045 PK04_097038 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B19 compound treatment 531520.0 8940.0 0.08 449520.0 -60500.0 -0.51 -0.3089 -0.5957 2141420 PK04_097039 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B20 compound treatment 483200.0 -39400.0 -0.34 492770.0 -17200.0 -0.15 -0.3402 -0.9308 2144377 PK04_097040 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B21 compound treatment 561090.0 38500.0 0.33 528750.0 18800.0 0.16 0.3442 0.945 2141808 PK04_097041 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B22 compound treatment 546110.0 23500.0 0.2 476270.0 -33700.0 -0.29 -0.0607 -0.1739 2143265 PK04_097042 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B23 compound treatment 475200.0 -47400.0 -0.4 510720.0 729.0 0.01 -0.2806 -0.6962 2141931 PK04_097043 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 B24 compound treatment 467070.0 -55500.0 -0.47 455270.0 -54700.0 -0.46 -0.6621 -1.0 2142705 PK04_097044 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C01 compound treatment 429620.0 -93000.0 -0.79 357600.0 -152000.0 -1.29 -1.4733 -0.9722 2141223 PK04_097045 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C02 compound treatment 448210.0 -74400.0 -0.63 488050.0 -21900.0 -0.19 -0.579 -0.8779 2141108 PK04_097046 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C03 compound treatment 179900.0 -343000.0 -2.92 188160.0 -322000.0 -2.73 -3.9918 -0.9995 2141329 PK04_097047 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C04 compound treatment 332910.0 -190000.0 -1.61 432710.0 -77300.0 -0.66 -1.6045 -0.9213 2141703 PK04_097048 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C05 compound treatment 397170.0 -125000.0 -1.07 375300.0 -135000.0 -1.14 -1.5623 -0.9994 2065845 PK04_097049 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C06 compound treatment 420320.0 -102000.0 -0.87 468640.0 -41400.0 -0.35 -0.8632 -0.9202 2141782 PK04_097050 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C07 compound treatment 412820.0 -110000.0 -0.93 381020.0 -129000.0 -1.09 -1.4339 -0.9969 2141574 PK04_097051 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C08 compound treatment 489340.0 -33200.0 -0.28 346900.0 -163000.0 -1.38 -1.1782 -0.8344 2141856 PK04_097052 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C09 compound treatment 265050.0 -258000.0 -2.19 311530.0 -198000.0 -1.68 -2.7396 -0.9915 2141751 PK04_097053 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C10 compound treatment 488020.0 -34600.0 -0.29 456850.0 -53100.0 -0.45 -0.5266 -0.9786 2141441 PK04_097054 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C11 mock treatment 439010.0 -83600.0 -0.71 430930.0 -79100.0 -0.67 -0.9769 -0.9996 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C12 mock treatment 489610.0 -33000.0 -0.28 507700.0 -2290.0 -0.02 -0.2121 -0.7543 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C13 compound treatment 463600.0 -59000.0 -0.5 433600.0 -76400.0 -0.65 -0.813 -0.992 2141937 PK04_097055 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C14 compound treatment 164210.0 -358000.0 -3.05 185470.0 -325000.0 -2.75 -4.1023 -0.9987 2141727 PK04_097056 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C15 mock treatment 484650.0 -37900.0 -0.32 437400.0 -72600.0 -0.62 -0.6636 -0.9545 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C16 mock treatment 491840.0 -30700.0 -0.26 461510.0 -48500.0 -0.41 -0.4757 -0.9761 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C17 compound treatment 507100.0 -15500.0 -0.13 407880.0 -102000.0 -0.87 -0.7056 -0.8054 2141078 PK04_097057 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C18 compound treatment 470040.0 -52500.0 -0.45 462810.0 -47200.0 -0.4 -0.5991 -0.9985 2141467 PK04_097058 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C19 compound treatment 543690.0 21100.0 0.18 469190.0 -40800.0 -0.35 -0.1177 -0.3019 2141339 PK04_097059 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C20 compound treatment 28370.0 -494000.0 -4.2 17210.0 -493000.0 -4.18 -5.9287 -1.0 2141364 PK04_097060 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C21 compound treatment 227740.0 -295000.0 -2.51 242770.0 -267000.0 -2.27 -3.3765 -0.9987 2141370 PK04_097061 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C22 compound treatment 499950.0 -22600.0 -0.19 383530.0 -126000.0 -1.07 -0.8947 -0.8209 2141489 PK04_097062 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C23 compound treatment 307220.0 -215000.0 -1.83 356760.0 -153000.0 -1.3 -2.2146 -0.9859 2141706 PK04_097063 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 C24 compound treatment 421680.0 -101000.0 -0.86 403270.0 -107000.0 -0.91 -1.2471 -0.9996 2141172 PK04_097064 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D01 compound treatment 444280.0 -78300.0 -0.67 528250.0 18300.0 0.15 -0.3615 -0.5286 2141788 PK04_097065 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D02 compound treatment 504720.0 -17900.0 -0.15 472850.0 -37100.0 -0.32 -0.3302 -0.9441 2143973 PK04_097066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D03 compound treatment 456080.0 -66500.0 -0.57 412450.0 -97500.0 -0.83 -0.9851 -0.9828 2141854 PK04_097067 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D04 compound treatment 378720.0 -144000.0 -1.22 373860.0 -136000.0 -1.15 -1.6819 -0.9996 2141969 PK04_097068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D05 compound treatment 578450.0 55900.0 0.48 496190.0 -13800.0 -0.12 0.2533 0.5175 2141087 PK04_097069 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D06 compound treatment 351330.0 -171000.0 -1.46 341920.0 -168000.0 -1.43 -2.0383 -0.9999 2144657 PK04_097070 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D07 compound treatment 484240.0 -38300.0 -0.33 465360.0 -44600.0 -0.38 -0.4983 -0.9972 2141768 PK04_097071 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D08 compound treatment 217440.0 -305000.0 -2.6 217300.0 -293000.0 -2.48 -3.5912 -0.9998 2144733 PK04_097072 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D09 compound treatment 406560.0 -116000.0 -0.99 401600.0 -108000.0 -0.92 -1.3481 -0.9994 2141552 PK04_097073 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D10 compound treatment 285010.0 -238000.0 -2.02 253190.0 -257000.0 -2.18 -2.9695 -0.9993 2143885 PK04_097074 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D11 mock treatment 445070.0 -77500.0 -0.66 399520.0 -110000.0 -0.94 -1.1289 -0.9852 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D12 mock treatment 468410.0 -54200.0 -0.46 535710.0 25700.0 0.22 -0.1716 -0.3365 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D13 compound treatment 505880.0 -16700.0 -0.14 490110.0 -19900.0 -0.17 -0.2197 -0.9964 2141513 PK04_097075 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D14 compound treatment 522490.0 -89.2 0.0 472800.0 -37200.0 -0.32 -0.2236 -0.7088 2144449 PK04_097076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D15 mock treatment 549190.0 26600.0 0.23 450950.0 -59000.0 -0.5 -0.1941 -0.3531 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D16 mock treatment 560440.0 37900.0 0.32 470290.0 -39700.0 -0.34 -0.0104 -0.0223 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D17 compound treatment 484490.0 -38100.0 -0.32 510240.0 249.0 0.0 -0.2276 -0.7025 2141816 PK04_097077 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D18 compound treatment 388990.0 -134000.0 -1.14 443100.0 -66900.0 -0.57 -1.2048 -0.9485 2142085 PK04_097078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D19 compound treatment 551930.0 29400.0 0.25 423310.0 -86700.0 -0.74 -0.3434 -0.4422 2141432 PK04_097079 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D20 compound treatment 437170.0 -85400.0 -0.73 416070.0 -93900.0 -0.8 -1.0771 -0.9989 2144825 PK04_097080 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D21 compound treatment 238830.0 -284000.0 -2.41 375680.0 -134000.0 -1.14 -2.5125 -0.9413 2141123 PK04_097081 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D22 compound treatment 358010.0 -165000.0 -1.4 334170.0 -176000.0 -1.49 -2.0446 -0.9995 2144893 PK04_097082 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D23 compound treatment 458280.0 -64300.0 -0.55 499460.0 -10500.0 -0.09 -0.45 -0.8118 2141421 PK04_097083 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 D24 compound treatment 465310.0 -57300.0 -0.49 495150.0 -14800.0 -0.13 -0.4335 -0.8615 2143085 PK04_097084 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E01 mock treatment 454240.0 -68300.0 -0.58 525780.0 15800.0 0.13 -0.3164 -0.5303 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E02 mock treatment 558580.0 36000.0 0.31 530570.0 20600.0 0.17 0.34 0.9645 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E03 compound treatment 412450.0 -110000.0 -0.94 427920.0 -82100.0 -0.7 -1.1548 -0.9893 2141878 PK04_097085 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E04 compound treatment 511200.0 -11400.0 -0.1 413700.0 -96300.0 -0.82 -0.646 -0.7854 2141520 PK04_097086 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E05 compound treatment 421850.0 -101000.0 -0.86 279040.0 -231000.0 -1.96 -1.9912 -0.9312 2141359 PK04_097087 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E06 compound treatment 253700.0 -269000.0 -2.29 138100.0 -372000.0 -3.15 -3.8481 -0.9875 2141507 PK04_097088 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E07 compound treatment 483000.0 -39600.0 -0.34 375620.0 -134000.0 -1.14 -1.0441 -0.8785 2141863 PK04_097089 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E08 compound treatment 462640.0 -59900.0 -0.51 513730.0 3740.0 0.03 -0.3381 -0.6618 2141163 PK04_097090 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E09 mock treatment 519640.0 -2940.0 -0.03 500440.0 -9550.0 -0.08 -0.075 -0.8842 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E10 mock treatment 576100.0 53500.0 0.46 527840.0 17800.0 0.15 0.429 0.8941 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E11 compound treatment 560980.0 38400.0 0.33 468610.0 -41400.0 -0.35 -0.0172 -0.0359 2141456 PK04_097091 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E12 compound treatment 204980.0 -318000.0 -2.7 141020.0 -369000.0 -3.13 -4.1237 -0.9973 2141683 PK04_097092 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E13 compound treatment 396870.0 -126000.0 -1.07 353710.0 -156000.0 -1.33 -1.6936 -0.9943 2141357 PK04_097093 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E14 compound treatment 121620.0 -401000.0 -3.41 113170.0 -397000.0 -3.37 -4.7922 -1.0 2141366 PK04_097094 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E15 compound treatment 349130.0 -173000.0 -1.48 363360.0 -147000.0 -1.24 -1.9229 -0.9964 2141575 PK04_097095 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E16 compound treatment 509160.0 -13400.0 -0.11 502240.0 -7750.0 -0.07 -0.1272 -0.9656 2141485 PK04_097096 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E17 mock treatment 423840.0 -98700.0 -0.84 505440.0 -4550.0 -0.04 -0.6213 -0.7388 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E18 mock treatment 544190.0 21600.0 0.18 455890.0 -54100.0 -0.46 -0.1945 -0.3934 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E19 compound treatment 353610.0 -169000.0 -1.44 290760.0 -219000.0 -1.86 -2.3314 -0.9919 2141377 PK04_097097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E20 compound treatment 281020.0 -242000.0 -2.06 239870.0 -270000.0 -2.29 -3.0734 -0.9985 2141326 PK04_097098 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E21 compound treatment 322160.0 -200000.0 -1.71 237940.0 -272000.0 -2.31 -2.8374 -0.9889 2141702 PK04_097099 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E22 compound treatment 501200.0 -21400.0 -0.18 363680.0 -146000.0 -1.24 -1.0062 -0.8022 2141417 PK04_097100 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E23 compound treatment 467570.0 -55000.0 -0.47 469440.0 -40600.0 -0.34 -0.5741 -0.9885 2141167 PK04_097101 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 E24 compound treatment 538480.0 15900.0 0.14 500400.0 -9590.0 -0.08 0.0381 0.2415 2141113 PK04_097102 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F01 mock treatment 528980.0 6400.0 0.05 526410.0 16400.0 0.14 0.137 0.916 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F02 mock treatment 566680.0 44100.0 0.38 237280.0 -273000.0 -2.31 -1.3705 -0.5848 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F03 compound treatment 240000.0 -283000.0 -2.4 274910.0 -235000.0 -1.99 -3.1099 -0.9957 2141216 PK04_097103 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F04 compound treatment 434470.0 -88100.0 -0.75 348290.0 -162000.0 -1.37 -1.4999 -0.9596 2142933 PK04_097104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F05 compound treatment 323650.0 -199000.0 -1.69 223330.0 -287000.0 -2.43 -2.9161 -0.9843 2141355 PK04_097105 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F06 compound treatment 295680.0 -227000.0 -1.93 277570.0 -232000.0 -1.97 -2.759 -0.9999 2142833 PK04_097106 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F07 compound treatment 512420.0 -10200.0 -0.09 422000.0 -88000.0 -0.75 -0.5889 -0.7837 2141414 PK04_097107 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F08 compound treatment 536550.0 14000.0 0.12 520800.0 10800.0 0.09 0.1489 0.9918 2144249 PK04_097108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F09 mock treatment 506840.0 -15700.0 -0.13 511090.0 1100.0 0.01 -0.0881 -0.6563 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F10 mock treatment 481990.0 -40600.0 -0.35 514810.0 4820.0 0.04 -0.2153 -0.6191 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F11 compound treatment 278200.0 -244000.0 -2.08 284440.0 -226000.0 -1.91 -2.823 -0.9991 2141568 PK04_097109 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F12 compound treatment 304170.0 -218000.0 -1.86 263040.0 -247000.0 -2.09 -2.7951 -0.9982 2142765 PK04_097110 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F13 compound treatment 446150.0 -76400.0 -0.65 508930.0 -1060.0 -0.01 -0.4661 -0.7168 2141348 PK04_097111 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F14 compound treatment 557070.0 34500.0 0.29 477990.0 -32000.0 -0.27 0.0155 0.0389 2142645 PK04_097112 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F15 compound treatment 387840.0 -135000.0 -1.15 299460.0 -211000.0 -1.79 -2.0733 -0.977 2141505 PK04_097113 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F16 compound treatment 516500.0 -6080.0 -0.05 497730.0 -12300.0 -0.1 -0.1101 -0.948 2142977 PK04_097114 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F17 mock treatment 541520.0 18900.0 0.16 483800.0 -26200.0 -0.22 -0.0432 -0.1573 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F18 mock treatment 540240.0 17700.0 0.15 530560.0 20600.0 0.17 0.2296 0.9972 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F19 compound treatment 518400.0 -4180.0 -0.04 414290.0 -95700.0 -0.81 -0.5992 -0.7374 2141200 PK04_097115 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F20 compound treatment 467200.0 -55400.0 -0.47 448510.0 -61500.0 -0.52 -0.7019 -0.9987 2142045 PK04_097116 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F21 compound treatment 456430.0 -66100.0 -0.56 459590.0 -50400.0 -0.43 -0.7002 -0.9908 2141938 PK04_097117 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F22 compound treatment 473640.0 -48900.0 -0.42 403940.0 -106000.0 -0.9 -0.9305 -0.9387 2144373 PK04_097118 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F23 compound treatment 452670.0 -69900.0 -0.59 462140.0 -47900.0 -0.41 -0.7076 -0.9827 2141419 PK04_097119 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 F24 compound treatment 300490.0 -222000.0 -1.89 362020.0 -148000.0 -1.26 -2.2235 -0.9803 2142769 PK04_097120 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G01 compound treatment 484320.0 -38300.0 -0.33 496680.0 -13300.0 -0.11 -0.31 -0.8998 2141178 PK04_097121 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G02 compound treatment 472810.0 -49800.0 -0.42 411060.0 -98900.0 -0.84 -0.8928 -0.9498 2141487 PK04_097122 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G03 mock treatment 525180.0 2600.0 0.02 577330.0 67300.0 0.57 0.4196 0.7339 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G04 mock treatment 545040.0 22500.0 0.19 487160.0 -22800.0 -0.19 -0.0018 -0.0067 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G05 compound treatment 500530.0 -22000.0 -0.19 369330.0 -141000.0 -1.19 -0.9763 -0.8083 2141519 PK04_097123 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G06 compound treatment 522790.0 211.0 0.0 495050.0 -14900.0 -0.13 -0.0883 -0.697 2141537 PK04_097124 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G07 compound treatment 276590.0 -246000.0 -2.09 292730.0 -217000.0 -1.84 -2.7829 -0.998 2141722 PK04_097125 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G08 compound treatment 307780.0 -215000.0 -1.83 395520.0 -114000.0 -0.97 -1.9788 -0.9562 2141577 PK04_097126 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G09 compound treatment 541980.0 19400.0 0.17 512000.0 2010.0 0.02 0.1288 0.776 2141458 PK04_097127 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G10 compound treatment 535880.0 13300.0 0.11 448510.0 -61500.0 -0.52 -0.2888 -0.5411 2141190 PK04_097128 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G11 compound treatment 348560.0 -174000.0 -1.48 308900.0 -201000.0 -1.71 -2.253 -0.9975 2141333 PK04_097129 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G12 compound treatment 371010.0 -152000.0 -1.29 460910.0 -49100.0 -0.42 -1.2062 -0.8902 2141508 PK04_097130 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G13 compound treatment 417810.0 -105000.0 -0.89 502320.0 -7670.0 -0.07 -0.6763 -0.7567 2141118 PK04_097131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G14 compound treatment 339960.0 -183000.0 -1.55 308590.0 -201000.0 -1.71 -2.3066 -0.9989 2141927 PK04_097132 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G15 compound treatment 401340.0 -121000.0 -1.03 507150.0 -2840.0 -0.02 -0.7464 -0.7234 2141159 PK04_097133 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G16 compound treatment 505640.0 -16900.0 -0.14 469920.0 -40100.0 -0.34 -0.3423 -0.927 2141713 PK04_097134 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G17 compound treatment 496490.0 -26100.0 -0.22 435520.0 -74500.0 -0.63 -0.6036 -0.9015 2141795 PK04_097135 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G18 compound treatment 442440.0 -80100.0 -0.68 428370.0 -81600.0 -0.69 -0.9717 -1.0 2141553 PK04_097136 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G19 mock treatment 539560.0 17000.0 0.14 508960.0 -1030.0 -0.01 0.096 0.6631 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G20 mock treatment 583130.0 60600.0 0.52 557760.0 47800.0 0.41 0.6508 0.9929 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G21 compound treatment 477460.0 -45100.0 -0.38 452970.0 -57000.0 -0.48 -0.6134 -0.9934 2141819 PK04_097137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G22 compound treatment 520500.0 -2080.0 -0.02 528900.0 18900.0 0.16 0.1009 0.6253 2141516 PK04_097138 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G23 compound treatment 507210.0 -15400.0 -0.13 527290.0 17300.0 0.15 0.0113 0.0575 2141691 PK04_097139 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 G24 compound treatment 226680.0 -296000.0 -2.52 306080.0 -204000.0 -1.73 -3.0031 -0.9832 2141155 PK04_097140 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H01 compound treatment 477060.0 -45500.0 -0.39 540040.0 30000.0 0.25 -0.0936 -0.2019 2141157 PK04_097141 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H02 compound treatment 514350.0 -8230.0 -0.07 351780.0 -158000.0 -1.34 -0.9985 -0.743 2143037 PK04_097142 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H03 mock treatment 402260.0 -120000.0 -1.02 502820.0 -7170.0 -0.06 -0.7668 -0.7478 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H04 mock treatment 492200.0 -30400.0 -0.26 516290.0 6300.0 0.05 -0.145 -0.5493 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H05 compound treatment 284420.0 -238000.0 -2.03 271160.0 -239000.0 -2.03 -2.8652 -1.0 2141926 PK04_097143 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H06 compound treatment 390080.0 -132000.0 -1.13 530800.0 20800.0 0.18 -0.6722 -0.5892 2143177 PK04_097144 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H07 compound treatment 292890.0 -230000.0 -1.95 240520.0 -269000.0 -2.29 -2.998 -0.997 2141694 PK04_097145 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H08 compound treatment 556000.0 33400.0 0.28 555000.0 45000.0 0.38 0.471 0.9895 2143025 PK04_097146 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H09 compound treatment 257200.0 -265000.0 -2.26 195160.0 -315000.0 -2.67 -3.4848 -0.9965 2141749 PK04_097147 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H10 compound treatment 581510.0 58900.0 0.5 331650.0 -178000.0 -1.51 -0.7152 -0.4488 2143077 PK04_097148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H11 compound treatment 248820.0 -274000.0 -2.33 172240.0 -338000.0 -2.87 -3.6727 -0.9947 2141097 PK04_097149 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H12 compound treatment 506320.0 -16300.0 -0.14 418330.0 -91700.0 -0.78 -0.6476 -0.82 2142913 PK04_097150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H13 compound treatment 463610.0 -59000.0 -0.5 373030.0 -137000.0 -1.16 -1.1762 -0.9295 2141401 PK04_097151 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H14 compound treatment 504840.0 -17700.0 -0.15 403620.0 -106000.0 -0.9 -0.7447 -0.8141 2143093 PK04_097152 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H15 compound treatment 561120.0 38500.0 0.33 471880.0 -38100.0 -0.32 0.0032 0.0071 2141777 PK04_097153 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H16 compound treatment 411310.0 -111000.0 -0.95 241130.0 -269000.0 -2.28 -2.282 -0.9242 2143865 PK04_097154 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H17 compound treatment 538080.0 15500.0 0.13 536260.0 26300.0 0.22 0.2508 0.9687 2141142 PK04_097155 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H18 compound treatment 561710.0 39100.0 0.33 518480.0 8490.0 0.07 0.2863 0.8406 2143925 PK04_097156 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H19 mock treatment 546510.0 23900.0 0.2 473570.0 -36400.0 -0.31 -0.0745 -0.2014 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H20 mock treatment 580060.0 57500.0 0.49 539790.0 29800.0 0.25 0.5245 0.9528 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H21 compound treatment 573300.0 50700.0 0.43 476270.0 -33700.0 -0.29 0.1029 0.1987 2141168 PK04_097157 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H22 compound treatment 554320.0 31700.0 0.27 494880.0 -15100.0 -0.13 0.1003 0.3356 2143057 PK04_097158 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H23 compound treatment 584520.0 61900.0 0.53 519140.0 9150.0 0.08 0.4275 0.8026 2141804 PK04_097159 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 H24 compound treatment 510080.0 -12500.0 -0.11 527640.0 17600.0 0.15 0.0307 0.167 2142649 PK04_097160 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I01 compound treatment 420180.0 -102000.0 -0.87 485850.0 -24100.0 -0.2 -0.7608 -0.8502 2141890 PK04_097161 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I02 compound treatment 563630.0 41100.0 0.35 456160.0 -53800.0 -0.46 -0.0759 -0.1321 2141465 PK04_097162 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I03 compound treatment 367170.0 -155000.0 -1.32 250680.0 -259000.0 -2.2 -2.4903 -0.9703 2141772 PK04_097163 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I04 compound treatment 457930.0 -64600.0 -0.55 469180.0 -40800.0 -0.35 -0.6337 -0.9751 2141343 PK04_097164 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I05 mock treatment 547810.0 25200.0 0.21 554410.0 44400.0 0.38 0.4182 0.9644 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I06 mock treatment 544280.0 21700.0 0.18 540640.0 30600.0 0.26 0.3144 0.9859 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I07 compound treatment 258120.0 -264000.0 -2.25 457240.0 -52800.0 -0.45 -1.9073 -0.8315 2141794 PK04_097165 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I08 compound treatment 502030.0 -20500.0 -0.17 329710.0 -180000.0 -1.53 -1.205 -0.7828 2141922 PK04_097166 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I09 compound treatment 618880.0 96300.0 0.82 450520.0 -59500.0 -0.5 0.2226 0.2313 2141780 PK04_097167 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I10 compound treatment 620520.0 97900.0 0.83 469120.0 -40900.0 -0.35 0.344 0.3812 2141799 PK04_097168 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I11 compound treatment 435040.0 -87500.0 -0.74 533600.0 23600.0 0.2 -0.385 -0.4992 2141177 PK04_097169 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I12 compound treatment 379120.0 -143000.0 -1.22 187210.0 -323000.0 -2.74 -2.7991 -0.9337 2141747 PK04_097170 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I13 compound treatment 597160.0 74600.0 0.63 425010.0 -85000.0 -0.72 -0.0611 -0.0636 2141423 PK04_097171 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I14 compound treatment 539900.0 17300.0 0.15 541320.0 31300.0 0.27 0.2921 0.9613 2141775 PK04_097172 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I15 compound treatment 509630.0 -12900.0 -0.11 456110.0 -53900.0 -0.46 -0.4011 -0.8531 2141538 PK04_097173 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I16 compound treatment 542270.0 19700.0 0.17 523920.0 13900.0 0.12 0.202 0.9854 2065871 PK04_097174 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I17 compound treatment 432000.0 -90600.0 -0.77 360220.0 -150000.0 -1.27 -1.4432 -0.9713 2141729 PK04_097175 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I18 compound treatment 618910.0 96300.0 0.82 490320.0 -19700.0 -0.17 0.4615 0.5518 2141892 PK04_097176 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I19 compound treatment 567080.0 44500.0 0.38 521670.0 11700.0 0.1 0.3378 0.8631 2141687 PK04_097177 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I20 compound treatment 588800.0 66200.0 0.56 493670.0 -16300.0 -0.14 0.3005 0.5179 2141680 PK04_097178 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I21 mock treatment 564200.0 41600.0 0.35 511280.0 1290.0 0.01 0.2581 0.7286 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I22 mock treatment 612190.0 89600.0 0.76 551170.0 41200.0 0.35 0.7861 0.9374 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I23 compound treatment 546010.0 23400.0 0.2 495920.0 -14100.0 -0.12 0.0566 0.2434 2141841 PK04_097179 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 I24 compound treatment 507760.0 -14800.0 -0.13 506880.0 -3110.0 -0.03 -0.1078 -0.837 2141766 PK04_097180 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J01 compound treatment 453510.0 -69100.0 -0.59 401350.0 -109000.0 -0.92 -1.0671 -0.9764 2141705 PK04_097181 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J02 compound treatment 299480.0 -223000.0 -1.9 206040.0 -304000.0 -2.58 -3.1652 -0.9886 2143397 PK04_097182 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J03 compound treatment 567530.0 45000.0 0.38 466080.0 -43900.0 -0.37 0.007 0.0131 2141179 PK04_097183 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J04 compound treatment 539250.0 16700.0 0.14 415700.0 -94300.0 -0.8 -0.4653 -0.5728 2144337 PK04_097184 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J05 mock treatment 557400.0 34800.0 0.3 545360.0 35400.0 0.3 0.4216 1.0 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J06 mock treatment 536330.0 13800.0 0.12 552450.0 42500.0 0.36 0.3374 0.891 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J07 compound treatment 583290.0 60700.0 0.52 424130.0 -85900.0 -0.73 -0.1498 -0.1678 2141805 PK04_097185 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J08 compound treatment 292000.0 -231000.0 -1.96 475540.0 -34500.0 -0.29 -1.5937 -0.8036 2143365 PK04_097186 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J09 compound treatment 394920.0 -128000.0 -1.09 266020.0 -244000.0 -2.07 -2.2313 -0.9547 2141901 PK04_097187 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J10 compound treatment 346000.0 -177000.0 -1.5 473140.0 -36900.0 -0.31 -1.2833 -0.8363 2144881 PK04_097188 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J11 compound treatment 539400.0 16800.0 0.14 403870.0 -106000.0 -0.9 -0.5353 -0.5873 2141717 PK04_097189 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J12 compound treatment 224450.0 -298000.0 -2.54 422970.0 -87000.0 -0.74 -2.3154 -0.8765 2143405 PK04_097190 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J13 compound treatment 600000.0 77400.0 0.66 507140.0 -2850.0 -0.02 0.4486 0.6807 2141188 PK04_097191 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J14 compound treatment 574490.0 51900.0 0.44 524370.0 14400.0 0.12 0.3985 0.8698 2142929 PK04_097192 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J15 compound treatment 508370.0 -14200.0 -0.12 491470.0 -18500.0 -0.16 -0.1966 -0.9916 2141365 PK04_097193 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J16 compound treatment 602490.0 79900.0 0.68 522110.0 12100.0 0.1 0.5534 0.8049 2144325 PK04_097194 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J17 compound treatment 355400.0 -167000.0 -1.42 298840.0 -211000.0 -1.79 -2.2722 -0.9935 2141221 PK04_097195 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J18 compound treatment 593660.0 71100.0 0.6 555470.0 45500.0 0.39 0.7004 0.9764 2143377 PK04_097196 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J19 compound treatment 529490.0 6910.0 0.06 548200.0 38200.0 0.32 0.2708 0.822 2141815 PK04_097197 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J20 compound treatment 387410.0 -135000.0 -1.15 328960.0 -181000.0 -1.54 -1.899 -0.9898 2142585 PK04_097198 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J21 mock treatment 528320.0 5740.0 0.05 514480.0 4490.0 0.04 0.0615 0.9924 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J22 mock treatment 437840.0 -84700.0 -0.72 479950.0 -30000.0 -0.25 -0.6899 -0.9023 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J23 compound treatment 564830.0 42300.0 0.36 460580.0 -49400.0 -0.42 -0.0422 -0.0765 2141186 PK04_097199 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 J24 compound treatment 491870.0 -30700.0 -0.26 511060.0 1070.0 0.01 -0.1783 -0.6821 2144237 PK04_097200 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K01 compound treatment 441340.0 -81200.0 -0.69 480480.0 -29500.0 -0.25 -0.6657 -0.9056 2141164 PK04_097201 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K02 compound treatment 570350.0 47800.0 0.41 502720.0 -7270.0 -0.06 0.2438 0.593 2141443 PK04_097202 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K03 compound treatment 429140.0 -93400.0 -0.79 297980.0 -212000.0 -1.8 -1.8338 -0.9326 2141548 PK04_097203 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K04 compound treatment 352600.0 -170000.0 -1.45 249160.0 -261000.0 -2.21 -2.587 -0.9788 2141351 PK04_097204 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K05 compound treatment 275420.0 -247000.0 -2.1 369070.0 -141000.0 -1.2 -2.3321 -0.9642 2141786 PK04_097205 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K06 compound treatment 225760.0 -297000.0 -2.53 350400.0 -160000.0 -1.35 -2.7428 -0.9573 2141746 PK04_097206 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K07 mock treatment 600860.0 78300.0 0.67 566340.0 56300.0 0.48 0.8089 0.9868 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K08 mock treatment 637720.0 115000.0 0.98 552500.0 42500.0 0.36 0.9476 0.9079 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K09 compound treatment 261600.0 -261000.0 -2.22 261820.0 -248000.0 -2.11 -3.0585 -0.9996 2141350 PK04_097207 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K10 compound treatment 404890.0 -118000.0 -1.0 263900.0 -246000.0 -2.09 -2.1841 -0.9434 2141331 PK04_097208 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K11 compound treatment 564540.0 42000.0 0.36 419840.0 -90200.0 -0.76 -0.2883 -0.3416 2141806 PK04_097209 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K12 compound treatment 524330.0 1750.0 0.01 469010.0 -41000.0 -0.35 -0.2353 -0.6762 2141720 PK04_097210 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K13 compound treatment 389860.0 -133000.0 -1.13 379330.0 -131000.0 -1.11 -1.5821 -1.0 2141904 PK04_097211 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccccc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K14 compound treatment 474720.0 -47900.0 -0.41 493730.0 -16300.0 -0.14 -0.3854 -0.8966 2141222 PK04_097212 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K15 mock treatment 605490.0 82900.0 0.71 414260.0 -95700.0 -0.81 -0.0755 -0.0702 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K16 mock treatment 519490.0 -3090.0 -0.03 564160.0 54200.0 0.46 0.3063 0.6656 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K17 compound treatment 540840.0 18300.0 0.16 510030.0 39.2 0.0 0.1101 0.7086 2141773 PK04_097213 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K18 compound treatment 609150.0 86600.0 0.74 616320.0 106000.0 0.9 1.1586 0.9949 2141524 PK04_097214 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K19 compound treatment 530190.0 7610.0 0.06 454050.0 -55900.0 -0.47 -0.2898 -0.605 2141218 PK04_097215 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K20 compound treatment 603930.0 81400.0 0.69 529320.0 19300.0 0.16 0.6053 0.8511 2141861 PK04_097216 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K21 compound treatment 498590.0 -24000.0 -0.2 483620.0 -26400.0 -0.22 -0.3025 -0.999 2141117 PK04_097217 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K22 compound treatment 530880.0 8300.0 0.07 290130.0 -220000.0 -1.87 -1.2688 -0.6798 2141354 PK04_097218 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K23 mock treatment 548640.0 26100.0 0.22 495600.0 -14400.0 -0.12 0.0705 0.2784 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 K24 mock treatment 571220.0 48600.0 0.41 525280.0 15300.0 0.13 0.3843 0.8862 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L01 compound treatment 378620.0 -144000.0 -1.22 330890.0 -179000.0 -1.52 -1.9403 -0.9943 2141684 PK04_097219 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L02 compound treatment 441120.0 -81500.0 -0.69 346050.0 -164000.0 -1.39 -1.4734 -0.9483 2143489 PK04_097220 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L03 compound treatment 107120.0 -415000.0 -3.53 104880.0 -405000.0 -3.44 -4.9292 -0.9999 2141375 PK04_097221 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L04 compound treatment 385090.0 -137000.0 -1.17 482110.0 -27900.0 -0.24 -0.9943 -0.8332 2143313 PK04_097222 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L05 compound treatment 309630.0 -213000.0 -1.81 403520.0 -106000.0 -0.9 -1.9196 -0.9483 2141889 PK04_097223 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L06 compound treatment 474560.0 -48000.0 -0.41 344080.0 -166000.0 -1.41 -1.284 -0.8762 2144793 PK04_097224 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L07 mock treatment 227130.0 -295000.0 -2.51 540500.0 30500.0 0.26 -1.5943 -0.631 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L08 mock treatment 560710.0 38100.0 0.32 466030.0 -44000.0 -0.37 -0.0343 -0.0694 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L09 compound treatment 599960.0 77400.0 0.66 524090.0 14100.0 0.12 0.5501 0.8221 2141438 PK04_097225 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L10 compound treatment 591330.0 68800.0 0.58 585920.0 75900.0 0.64 0.869 0.9988 2142993 PK04_097226 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L11 compound treatment 325550.0 -197000.0 -1.68 208000.0 -302000.0 -2.56 -2.9966 -0.9789 2141185 PK04_097227 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L12 compound treatment 470820.0 -51800.0 -0.44 458880.0 -51100.0 -0.43 -0.6179 -1.0 2144653 PK04_097228 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L13 compound treatment 589720.0 67100.0 0.57 499040.0 -11000.0 -0.09 0.3382 0.5844 2141893 PK04_097229 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L14 compound treatment 551520.0 28900.0 0.25 402080.0 -108000.0 -0.92 -0.4732 -0.4992 2143417 PK04_097230 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L15 mock treatment 364670.0 -158000.0 -1.34 318130.0 -192000.0 -1.63 -2.1007 -0.9955 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L16 mock treatment 430200.0 -92400.0 -0.79 541160.0 31200.0 0.26 -0.3688 -0.4447 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L17 compound treatment 514500.0 -8080.0 -0.07 429120.0 -80900.0 -0.69 -0.5337 -0.7741 2141152 PK04_097231 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L18 compound treatment 423300.0 -99300.0 -0.84 405950.0 -104000.0 -0.88 -1.2213 -0.9998 2143325 PK04_097232 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L19 compound treatment 507430.0 -15100.0 -0.13 435810.0 -74200.0 -0.63 -0.5361 -0.8346 2141709 PK04_097233 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L20 compound treatment 376330.0 -146000.0 -1.24 315360.0 -195000.0 -1.65 -2.0472 -0.9903 2142773 PK04_097234 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L21 compound treatment 532360.0 9780.0 0.08 500820.0 -9170.0 -0.08 0.0038 0.0336 2141174 PK04_097235 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L22 compound treatment 477990.0 -44600.0 -0.38 511450.0 1460.0 0.01 -0.2595 -0.6837 2142985 PK04_097236 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L23 mock treatment 493600.0 -29000.0 -0.25 521360.0 11400.0 0.1 -0.1061 -0.4009 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 L24 mock treatment 516450.0 -6130.0 -0.05 451590.0 -58400.0 -0.5 -0.3872 -0.7772 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M01 compound treatment 259900.0 -263000.0 -2.23 468980.0 -41000.0 -0.35 -1.8262 -0.8075 2141838 PK04_097237 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M02 compound treatment 473600.0 -49000.0 -0.42 543140.0 33100.0 0.28 -0.0958 -0.1906 2141189 PK04_097238 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M03 compound treatment 295970.0 -227000.0 -1.93 448110.0 -61900.0 -0.52 -1.7344 -0.868 2141724 PK04_097239 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M04 compound treatment 251100.0 -271000.0 -2.31 303870.0 -206000.0 -1.75 -2.8695 -0.9906 2141153 PK04_097240 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M05 compound treatment 511100.0 -11500.0 -0.1 520960.0 11000.0 0.09 -0.0033 -0.0242 2141436 PK04_097241 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M06 compound treatment 382720.0 -140000.0 -1.19 460420.0 -49600.0 -0.42 -1.1387 -0.9023 2141769 PK04_097242 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M07 compound treatment 270850.0 -252000.0 -2.14 507360.0 -2630.0 -0.02 -1.5301 -0.7144 2141771 PK04_097243 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(O)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M08 compound treatment 455040.0 -67500.0 -0.57 512960.0 2970.0 0.03 -0.3885 -0.6755 2141480 PK04_097244 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M09 mock treatment 483550.0 -39000.0 -0.33 574430.0 64400.0 0.55 0.1517 0.2372 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M10 mock treatment 625790.0 103000.0 0.88 572220.0 62200.0 0.53 0.9941 0.9704 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M11 compound treatment 249470.0 -273000.0 -2.32 299930.0 -210000.0 -1.78 -2.9029 -0.9914 2141571 PK04_097245 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M12 compound treatment 269680.0 -253000.0 -2.15 277080.0 -233000.0 -1.98 -2.9184 -0.9991 2141879 PK04_097246 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M13 mock treatment 592050.0 69500.0 0.59 567740.0 57700.0 0.49 0.7643 0.9957 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M14 mock treatment 551610.0 29000.0 0.25 567290.0 57300.0 0.49 0.5183 0.9507 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M15 compound treatment 451960.0 -70600.0 -0.6 465180.0 -44800.0 -0.38 -0.6936 -0.9756 2141832 PK04_097247 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M16 compound treatment 403940.0 -119000.0 -1.01 556480.0 46500.0 0.39 -0.4348 -0.4013 2141542 PK04_097248 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M17 compound treatment 344870.0 -178000.0 -1.51 376600.0 -133000.0 -1.13 -1.8691 -0.9898 2141399 PK04_097249 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M18 compound treatment 540330.0 17800.0 0.15 531610.0 21600.0 0.18 0.2365 0.9953 2141903 PK04_097250 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M19 compound treatment 26790.0 -496000.0 -4.22 64640.0 -445000.0 -3.78 -5.6538 -0.9985 2141716 PK04_097251 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M20 compound treatment 524960.0 2380.0 0.02 412570.0 -97400.0 -0.83 -0.57 -0.6896 2141203 PK04_097252 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M21 compound treatment 506080.0 -16500.0 -0.14 429150.0 -80800.0 -0.69 -0.5842 -0.8345 2141110 PK04_097253 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M22 compound treatment 352160.0 -170000.0 -1.45 390480.0 -120000.0 -1.01 -1.742 -0.9847 2141731 PK04_097254 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M23 compound treatment 451720.0 -70900.0 -0.6 472420.0 -37600.0 -0.32 -0.6516 -0.9556 2141095 PK04_097255 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 M24 compound treatment 455230.0 -67300.0 -0.57 477410.0 -32600.0 -0.28 -0.6006 -0.9441 2141894 PK04_097256 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N01 compound treatment 492130.0 -30400.0 -0.26 547420.0 37400.0 0.32 0.0413 0.1009 2141340 PK04_097257 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N02 compound treatment 470360.0 -52200.0 -0.44 479840.0 -30200.0 -0.26 -0.495 -0.9656 2142089 PK04_097258 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N03 compound treatment 519470.0 -3110.0 -0.03 397600.0 -112000.0 -0.95 -0.6928 -0.7264 2141511 PK04_097259 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCc%10cc(OC)c(OC)cc%10C9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N04 compound treatment 410880.0 -112000.0 -0.95 528910.0 18900.0 0.16 -0.5585 -0.5795 2144305 PK04_097260 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N05 compound treatment 390760.0 -132000.0 -1.12 324340.0 -186000.0 -1.57 -1.9065 -0.9862 2141839 PK04_097261 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N06 compound treatment 346810.0 -176000.0 -1.5 487320.0 -22700.0 -0.19 -1.1933 -0.7915 2142057 PK04_097262 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N07 compound treatment 529720.0 7140.0 0.06 537410.0 27400.0 0.23 0.2074 0.8628 2141431 PK04_097263 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N08 compound treatment 458490.0 -64100.0 -0.55 518910.0 8920.0 0.08 -0.332 -0.6032 2144369 PK04_097264 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N09 mock treatment 570640.0 48100.0 0.41 567440.0 57400.0 0.49 0.6337 0.9962 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N10 mock treatment 567210.0 44600.0 0.38 539140.0 29100.0 0.25 0.4433 0.9784 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N11 compound treatment 456240.0 -66300.0 -0.56 471910.0 -38100.0 -0.32 -0.6275 -0.965 2141527 PK04_097265 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N12 compound treatment 488450.0 -34100.0 -0.29 501060.0 -8930.0 -0.08 -0.2589 -0.8627 2144009 PK04_097266 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N13 mock treatment 573820.0 51200.0 0.44 522600.0 12600.0 0.11 0.3839 0.8552 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N14 mock treatment 541980.0 19400.0 0.17 560320.0 50300.0 0.43 0.4186 0.9145 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N15 compound treatment 517300.0 -5280.0 -0.04 404260.0 -106000.0 -0.9 -0.666 -0.7416 2141907 PK04_097267 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N16 compound treatment 523100.0 521.0 0.0 475090.0 -34900.0 -0.3 -0.2062 -0.6964 2143157 PK04_097268 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N17 compound treatment 480280.0 -42300.0 -0.36 517320.0 7330.0 0.06 -0.2105 -0.5764 2141544 PK04_097269 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N18 compound treatment 530960.0 8380.0 0.07 470820.0 -39200.0 -0.33 -0.1845 -0.543 2144297 PK04_097270 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N19 compound treatment 525890.0 3310.0 0.03 516820.0 6830.0 0.06 0.0609 0.9451 2141483 PK04_097271 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N20 compound treatment 488170.0 -34400.0 -0.29 420800.0 -89200.0 -0.76 -0.742 -0.9146 2142217 PK04_097272 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N21 compound treatment 534740.0 12200.0 0.1 495040.0 -15000.0 -0.13 -0.0165 -0.101 2141887 PK04_097273 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccccc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N22 compound treatment 528650.0 6070.0 0.05 500060.0 -9930.0 -0.08 -0.023 -0.2332 2143065 PK04_097274 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N23 compound treatment 479710.0 -42900.0 -0.36 501980.0 -8010.0 -0.07 -0.3059 -0.8247 2141817 PK04_097275 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 N24 compound treatment 457050.0 -65500.0 -0.56 476480.0 -33500.0 -0.28 -0.5952 -0.9512 2144333 PK04_097276 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O01 compound treatment 503070.0 -19500.0 -0.17 447680.0 -62300.0 -0.53 -0.4911 -0.8865 2141166 PK04_097277 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O02 compound treatment 348600.0 -174000.0 -1.48 357920.0 -152000.0 -1.29 -1.9587 -0.9977 2141900 PK04_097278 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O03 compound treatment 477660.0 -44900.0 -0.38 507570.0 -2420.0 -0.02 -0.2847 -0.744 2141790 PK04_097279 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O04 compound treatment 288050.0 -235000.0 -2.0 327040.0 -183000.0 -1.55 -2.5082 -0.9923 2141883 PK04_097280 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCN(CC4)c5ncccn5)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O05 compound treatment 239240.0 -283000.0 -2.41 205760.0 -304000.0 -2.58 -3.5293 -0.9994 2141427 PK04_097281 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O06 compound treatment 408400.0 -114000.0 -0.97 402350.0 -108000.0 -0.91 -1.3325 -0.9995 2141093 PK04_097282 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@H]([C@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O07 compound treatment 413310.0 -109000.0 -0.93 411480.0 -98500.0 -0.84 -1.2482 -0.9986 2141812 PK04_097283 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O08 compound treatment 230010.0 -293000.0 -2.49 443270.0 -66700.0 -0.57 -2.1602 -0.8463 2141430 PK04_097284 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O09 compound treatment 497240.0 -25300.0 -0.22 501940.0 -8050.0 -0.07 -0.2007 -0.8876 2141454 PK04_097285 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O10 compound treatment 430780.0 -91800.0 -0.78 456280.0 -53700.0 -0.46 -0.8744 -0.9671 2141529 PK04_097286 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O11 mock treatment 424560.0 -98000.0 -0.83 474650.0 -35300.0 -0.3 -0.8016 -0.9046 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O12 mock treatment 498320.0 -24300.0 -0.21 499700.0 -10300.0 -0.09 -0.2077 -0.9267 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O13 compound treatment 333810.0 -189000.0 -1.61 439720.0 -70300.0 -0.6 -1.5571 -0.909 2141368 PK04_097287 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O14 compound treatment 492500.0 -30100.0 -0.26 459700.0 -50300.0 -0.43 -0.4826 -0.9701 2141362 PK04_097288 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O15 compound treatment 444160.0 -78400.0 -0.67 266750.0 -243000.0 -2.06 -1.9307 -0.8904 2141460 PK04_097289 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O16 compound treatment 447930.0 -74600.0 -0.64 225070.0 -285000.0 -2.42 -2.1581 -0.8636 2141860 PK04_097290 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccccc76)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O17 compound treatment 413600.0 -109000.0 -0.93 307390.0 -203000.0 -1.72 -1.8708 -0.958 2141175 PK04_097291 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O18 compound treatment 393610.0 -129000.0 -1.1 399120.0 -111000.0 -0.94 -1.4408 -0.9971 2141486 PK04_097292 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O19 compound treatment 215680.0 -307000.0 -2.61 251260.0 -259000.0 -2.19 -3.3981 -0.9963 2141156 PK04_097293 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(OCCO)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O20 compound treatment 416160.0 -106000.0 -0.91 405280.0 -105000.0 -0.89 -1.2682 -1.0 2141685 PK04_097294 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O21 compound treatment 352800.0 -170000.0 -1.44 306200.0 -204000.0 -1.73 -2.2437 -0.996 2141094 PK04_097295 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O22 compound treatment 323610.0 -199000.0 -1.69 247520.0 -262000.0 -2.23 -2.7713 -0.9909 2141379 PK04_097296 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@@H]([C@@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O23 compound treatment 247450.0 -275000.0 -2.34 241190.0 -269000.0 -2.28 -3.2674 -0.9999 2141397 PK04_097297 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccccc3OCCO)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 O24 compound treatment 287570.0 -235000.0 -2.0 319230.0 -191000.0 -1.62 -2.5579 -0.9945 2065842 PK04_097298 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P01 compound treatment 167320.0 -355000.0 -3.02 168190.0 -342000.0 -2.9 -4.1873 -0.9998 2141898 PK04_097299 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P02 compound treatment 264560.0 -258000.0 -2.2 225060.0 -285000.0 -2.42 -3.2612 -0.9988 2143305 PK04_097300 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P03 compound treatment 258300.0 -264000.0 -2.25 262200.0 -248000.0 -2.1 -3.0761 -0.9994 2141555 PK04_097301 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)[C@H]([C@H](OC4=O)c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P04 compound treatment 242830.0 -280000.0 -2.38 240280.0 -270000.0 -2.29 -3.3006 -0.9998 2144945 PK04_097302 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P05 compound treatment 88390.0 -434000.0 -3.69 97860.0 -412000.0 -3.5 -5.0839 -0.9996 2141923 PK04_097303 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P06 compound treatment 333540.0 -189000.0 -1.61 217780.0 -292000.0 -2.48 -2.8899 -0.9781 2144433 PK04_097304 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P07 compound treatment 223840.0 -299000.0 -2.54 225660.0 -284000.0 -2.41 -3.5026 -0.9997 2141482 PK04_097305 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P08 compound treatment 262160.0 -260000.0 -2.22 329520.0 -180000.0 -1.53 -2.6491 -0.9837 2143929 PK04_097306 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P09 compound treatment 315900.0 -207000.0 -1.76 262800.0 -247000.0 -2.1 -2.726 -0.9962 2141698 PK04_097307 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P10 compound treatment 267430.0 -255000.0 -2.17 324030.0 -186000.0 -1.58 -2.6503 -0.9877 2142653 PK04_097308 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P11 mock treatment 359610.0 -163000.0 -1.39 277050.0 -233000.0 -1.98 -2.3776 -0.985 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P12 mock treatment 344450.0 -178000.0 -1.52 281210.0 -229000.0 -1.94 -2.4438 -0.9925 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P13 compound treatment 346170.0 -176000.0 -1.5 317570.0 -192000.0 -1.63 -2.2154 -0.9991 2141449 PK04_097309 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P14 compound treatment 282190.0 -240000.0 -2.05 285350.0 -225000.0 -1.91 -2.7935 -0.9994 2144933 PK04_097310 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P15 compound treatment 333400.0 -189000.0 -1.61 272640.0 -237000.0 -2.01 -2.5617 -0.9938 2141416 PK04_097311 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccc(O)cc6)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P16 compound treatment 272720.0 -250000.0 -2.13 243540.0 -266000.0 -2.26 -3.1013 -0.9995 2144445 PK04_097312 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P17 compound treatment 263860.0 -259000.0 -2.2 227520.0 -282000.0 -2.4 -3.2507 -0.9991 2141453 PK04_097313 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P18 compound treatment 159440.0 -363000.0 -3.09 181440.0 -329000.0 -2.79 -4.1552 -0.9987 2142745 PK04_097314 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P19 compound treatment 197440.0 -325000.0 -2.77 228700.0 -281000.0 -2.39 -3.6431 -0.9973 2141541 PK04_097315 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P20 compound treatment 200090.0 -322000.0 -2.74 238810.0 -271000.0 -2.3 -3.5665 -0.9962 2142193 PK04_097316 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P21 compound treatment 237600.0 -285000.0 -2.42 209000.0 -301000.0 -2.55 -3.5197 -0.9997 2141134 PK04_097317 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P22 compound treatment 291580.0 -231000.0 -1.97 267710.0 -242000.0 -2.06 -2.8428 -0.9997 2142729 PK04_097318 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P23 compound treatment 230240.0 -292000.0 -2.49 248070.0 -262000.0 -2.22 -3.3296 -0.9984 2141121 PK04_097319 OC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2097 P24 compound treatment 219480.0 -303000.0 -2.58 209690.0 -300000.0 -2.55 -3.6246 -1.0 2144273 PK04_097320 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A01 compound treatment 314460.0 -201000.0 -1.71 434140.0 -87400.0 -0.74 -1.7305 -0.9303 2141696 PK04_098001 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A02 compound treatment 258410.0 -257000.0 -2.18 326000.0 -196000.0 -1.66 -2.7164 -0.9908 2144133 PK04_098002 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A03 compound treatment 316320.0 -199000.0 -1.69 378840.0 -143000.0 -1.21 -2.051 -0.9866 2141089 PK04_098003 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A04 compound treatment 390770.0 -124000.0 -1.06 398150.0 -123000.0 -1.05 -1.4874 -1.0 2142093 PK04_098004 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A05 compound treatment 270400.0 -245000.0 -2.08 218040.0 -303000.0 -2.57 -3.2918 -0.9944 2141744 PK04_098005 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A06 compound treatment 446720.0 -68300.0 -0.58 294260.0 -227000.0 -1.93 -1.7739 -0.8811 2143237 PK04_098006 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A07 compound treatment 436330.0 -78700.0 -0.67 502560.0 -18900.0 -0.16 -0.587 -0.8526 2141337 PK04_098007 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A08 compound treatment 288320.0 -227000.0 -1.93 219070.0 -302000.0 -2.57 -3.1778 -0.9901 2144129 PK04_098008 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A09 compound treatment 370930.0 -144000.0 -1.23 486330.0 -35200.0 -0.3 -1.0778 -0.8543 2141791 PK04_098009 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A10 compound treatment 508160.0 -6860.0 -0.06 499490.0 -22000.0 -0.19 -0.1733 -0.8858 2144193 PK04_098010 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A11 compound treatment 290210.0 -225000.0 -1.91 281050.0 -240000.0 -2.04 -2.7947 -0.9995 2141133 PK04_098011 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A12 compound treatment 352380.0 -163000.0 -1.38 308270.0 -213000.0 -1.81 -2.2574 -0.9912 2143993 PK04_098012 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A13 mock treatment 268500.0 -247000.0 -2.1 417810.0 -104000.0 -0.88 -2.105 -0.9256 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A14 mock treatment 423360.0 -91700.0 -0.78 338360.0 -183000.0 -1.55 -1.6499 -0.9492 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A15 compound treatment 381370.0 -134000.0 -1.14 461870.0 -59600.0 -0.51 -1.1617 -0.9335 2141695 PK04_098013 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A16 compound treatment 269180.0 -246000.0 -2.09 399780.0 -122000.0 -1.03 -2.209 -0.9471 2144913 PK04_098014 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A17 compound treatment 210100.0 -305000.0 -2.59 452880.0 -68600.0 -0.58 -2.2459 -0.8448 2141801 PK04_098015 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A18 compound treatment 319280.0 -196000.0 -1.67 296640.0 -225000.0 -1.91 -2.5263 -0.9977 2142117 PK04_098016 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A19 compound treatment 402270.0 -113000.0 -0.96 380130.0 -141000.0 -1.2 -1.5263 -0.9939 2141835 PK04_098017 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A20 compound treatment 407200.0 -108000.0 -0.92 392010.0 -129000.0 -1.1 -1.4254 -0.996 2144205 PK04_098018 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A21 compound treatment 313040.0 -202000.0 -1.72 288050.0 -233000.0 -1.98 -2.6154 -0.9975 2141920 PK04_098019 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccccc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A22 compound treatment 320480.0 -195000.0 -1.66 414690.0 -107000.0 -0.91 -1.811 -0.9598 2141945 PK04_098020 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A23 compound treatment 255750.0 -259000.0 -2.21 239230.0 -282000.0 -2.39 -3.2528 -0.9992 2141111 PK04_098021 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)O)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 A24 compound treatment 224420.0 -291000.0 -2.47 291840.0 -230000.0 -1.95 -3.1257 -0.993 2143385 PK04_098022 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B01 compound treatment 334650.0 -180000.0 -1.53 356970.0 -165000.0 -1.4 -2.072 -0.9989 2142845 PK04_098023 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B02 compound treatment 515040.0 19.2 0.0 536060.0 14600.0 0.12 0.0874 0.708 2143009 PK04_098024 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B03 compound treatment 440590.0 -74400.0 -0.63 535930.0 14400.0 0.12 -0.3612 -0.5601 2144209 PK04_098025 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B04 compound treatment 483840.0 -31200.0 -0.27 494460.0 -27000.0 -0.23 -0.3498 -0.9974 2142037 PK04_098026 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B05 compound treatment 543450.0 28400.0 0.24 257730.0 -264000.0 -2.24 -1.4112 -0.627 2144313 PK04_098027 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B06 compound treatment 272960.0 -242000.0 -2.06 259720.0 -262000.0 -2.22 -3.0264 -0.9993 2143245 PK04_098028 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B07 compound treatment 484510.0 -30500.0 -0.26 395960.0 -126000.0 -1.06 -0.9366 -0.8544 2144661 PK04_098029 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B08 compound treatment 491200.0 -23800.0 -0.2 342400.0 -179000.0 -1.52 -1.2176 -0.7944 2143409 PK04_098030 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B09 compound treatment 497060.0 -18000.0 -0.15 414360.0 -107000.0 -0.91 -0.7507 -0.8145 2144745 PK04_098031 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B10 compound treatment 554850.0 39800.0 0.34 539740.0 18200.0 0.15 0.349 0.9369 2143049 PK04_098032 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B11 compound treatment 466130.0 -48900.0 -0.42 524680.0 3170.0 0.03 -0.2751 -0.66 2143257 PK04_098033 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B12 compound treatment 347810.0 -167000.0 -1.42 450620.0 -70900.0 -0.6 -1.4311 -0.9266 2141502 PK04_098034 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B13 mock treatment 549020.0 34000.0 0.29 538590.0 17100.0 0.14 0.307 0.9489 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B14 mock treatment 521330.0 6310.0 0.05 577630.0 56100.0 0.48 0.3746 0.7819 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B15 compound treatment 376450.0 -139000.0 -1.18 388090.0 -133000.0 -1.13 -1.6338 -0.9998 2142113 PK04_098035 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B16 compound treatment 464400.0 -50600.0 -0.43 450850.0 -70700.0 -0.6 -0.7283 -0.9868 2141859 PK04_098036 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccccc54)[C@@H]([C@@H](OC2=O)c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B17 compound treatment 356320.0 -159000.0 -1.35 336000.0 -186000.0 -1.57 -2.0674 -0.9971 2144033 PK04_098037 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B18 compound treatment 442840.0 -72200.0 -0.61 541860.0 20400.0 0.17 -0.3121 -0.4893 2141540 PK04_098038 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B19 compound treatment 511760.0 -3260.0 -0.03 514490.0 -7020.0 -0.06 -0.0617 -0.9396 2144437 PK04_098039 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B20 compound treatment 170260.0 -345000.0 -2.93 202520.0 -319000.0 -2.71 -3.9873 -0.9992 2144725 PK04_098040 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B21 compound treatment 448960.0 -66100.0 -0.56 425120.0 -96400.0 -0.82 -0.9755 -0.9833 2143413 PK04_098041 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B22 compound treatment 518450.0 3430.0 0.03 433180.0 -88300.0 -0.75 -0.5092 -0.6791 2141509 PK04_098042 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccc(OCCO)cc6)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCN(CC9)c%10ncccn%10)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B23 compound treatment 429180.0 -85800.0 -0.73 456160.0 -65300.0 -0.55 -0.9084 -0.9908 2142009 PK04_098043 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 B24 compound treatment 513800.0 -1220.0 -0.01 530760.0 9250.0 0.08 0.0482 0.6082 2141342 PK04_098044 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C01 compound treatment 473570.0 -41500.0 -0.35 471000.0 -50500.0 -0.43 -0.5523 -0.9953 2141145 PK04_098045 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C02 compound treatment 228350.0 -287000.0 -2.44 403300.0 -118000.0 -1.0 -2.4335 -0.9229 2143097 PK04_098046 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C03 compound treatment 425640.0 -89400.0 -0.76 292910.0 -229000.0 -1.94 -1.9089 -0.9164 2141834 PK04_098047 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C04 compound treatment 204390.0 -311000.0 -2.64 217830.0 -304000.0 -2.58 -3.6901 -0.9999 2142605 PK04_098048 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C05 compound treatment 363150.0 -152000.0 -1.29 222260.0 -299000.0 -2.54 -2.7085 -0.9509 2141398 PK04_098049 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C06 compound treatment 275330.0 -240000.0 -2.04 450080.0 -71400.0 -0.61 -1.8703 -0.8792 2143013 PK04_098050 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C07 compound treatment 411070.0 -104000.0 -0.88 465540.0 -56000.0 -0.47 -0.961 -0.9575 2141793 PK04_098051 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CCCO)cc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C08 compound treatment 499320.0 -15700.0 -0.13 475810.0 -45700.0 -0.39 -0.3686 -0.8989 2143277 PK04_098052 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C09 compound treatment 345190.0 -170000.0 -1.44 293220.0 -228000.0 -1.94 -2.3909 -0.9896 2141681 PK04_098053 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NC[C@H](O)c9ccccc9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C10 compound treatment 193310.0 -322000.0 -2.74 372450.0 -149000.0 -1.26 -2.8294 -0.9385 2144125 PK04_098054 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C11 mock treatment 464400.0 -50600.0 -0.43 328680.0 -193000.0 -1.64 -1.4611 -0.8638 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C12 mock treatment 461120.0 -53900.0 -0.46 515130.0 -6380.0 -0.05 -0.3625 -0.7851 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C13 compound treatment 298040.0 -217000.0 -1.85 223160.0 -298000.0 -2.53 -3.0948 -0.988 2141376 PK04_098055 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C14 compound treatment 525440.0 10400.0 0.09 506160.0 -15300.0 -0.13 -0.0294 -0.1866 2143897 PK04_098056 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C15 mock treatment 442400.0 -72600.0 -0.62 489800.0 -31700.0 -0.27 -0.627 -0.9306 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C16 mock treatment 482800.0 -32200.0 -0.27 387400.0 -134000.0 -1.14 -0.9982 -0.8531 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C17 compound treatment 534960.0 19900.0 0.17 513660.0 -7850.0 -0.07 0.0729 0.3999 2141461 PK04_098057 O[C@@H](CNC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(O)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C18 compound treatment 493560.0 -21500.0 -0.18 494450.0 -27100.0 -0.23 -0.2914 -0.9936 2143145 PK04_098058 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C19 compound treatment 215930.0 -299000.0 -2.54 259800.0 -262000.0 -2.22 -3.369 -0.9977 2141551 PK04_098059 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C20 compound treatment 384800.0 -130000.0 -1.11 426090.0 -95400.0 -0.81 -1.3557 -0.9881 2144941 PK04_098060 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C21 compound treatment 355400.0 -160000.0 -1.36 257190.0 -264000.0 -2.24 -2.5456 -0.9711 2141535 PK04_098061 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C22 compound treatment 316740.0 -198000.0 -1.69 291740.0 -230000.0 -1.95 -2.571 -0.9974 2142185 PK04_098062 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C23 compound treatment 473860.0 -41200.0 -0.35 432640.0 -88900.0 -0.75 -0.7807 -0.9392 2141425 PK04_098063 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 C24 compound treatment 488110.0 -26900.0 -0.23 536910.0 15400.0 0.13 -0.0695 -0.2637 2144353 PK04_098064 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D01 compound treatment 487540.0 -27500.0 -0.23 455770.0 -65700.0 -0.56 -0.5596 -0.9255 2143317 PK04_098065 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D02 compound treatment 253380.0 -262000.0 -2.23 319170.0 -202000.0 -1.72 -2.7876 -0.9918 2144805 PK04_098066 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D03 compound treatment 494480.0 -20500.0 -0.17 516490.0 -5020.0 -0.04 -0.1537 -0.8544 2142937 PK04_098067 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D04 compound treatment 508770.0 -6250.0 -0.05 386240.0 -135000.0 -1.15 -0.849 -0.7391 2141997 PK04_098068 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D05 compound treatment 435400.0 -79600.0 -0.68 360480.0 -161000.0 -1.37 -1.4448 -0.9476 2144781 PK04_098069 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D06 compound treatment 196250.0 -319000.0 -2.71 230040.0 -291000.0 -2.47 -3.6659 -0.9989 2144025 PK04_098070 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D07 compound treatment 362180.0 -153000.0 -1.3 227460.0 -294000.0 -2.49 -2.6832 -0.9539 2144817 PK04_098071 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D08 compound treatment 469120.0 -45900.0 -0.39 482990.0 -38500.0 -0.33 -0.5072 -0.9961 2144197 PK04_098072 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D09 compound treatment 448910.0 -66100.0 -0.56 466050.0 -55500.0 -0.47 -0.7303 -0.9961 2144761 PK04_098073 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D10 compound treatment 337760.0 -177000.0 -1.51 336800.0 -185000.0 -1.57 -2.1742 -0.9998 2142125 PK04_098074 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D11 mock treatment 470480.0 -44500.0 -0.38 464340.0 -57200.0 -0.48 -0.6108 -0.9926 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D12 mock treatment 554250.0 39200.0 0.33 545120.0 23600.0 0.2 0.3776 0.9702 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D13 compound treatment 474850.0 -40200.0 -0.34 429390.0 -92100.0 -0.78 -0.7942 -0.9312 2143225 PK04_098075 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D14 compound treatment 511600.0 -3420.0 -0.03 522300.0 792.0 0.01 -0.0158 -0.53 2144233 PK04_098076 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D15 mock treatment 572220.0 57200.0 0.49 492480.0 -29000.0 -0.25 0.17 0.3117 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D16 mock treatment 542040.0 27000.0 0.23 484600.0 -36900.0 -0.31 -0.0588 -0.1515 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D17 compound treatment 517960.0 2940.0 0.03 551080.0 29600.0 0.25 0.1951 0.7738 2143045 PK04_098077 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D18 compound treatment 512840.0 -2180.0 -0.02 482080.0 -39400.0 -0.33 -0.2496 -0.7452 2142013 PK04_098078 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D19 compound treatment 466740.0 -48300.0 -0.41 397190.0 -124000.0 -1.05 -1.0361 -0.9155 2142213 PK04_098079 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D20 compound treatment 521490.0 6470.0 0.06 612040.0 90500.0 0.77 0.5819 0.7558 2141447 PK04_098080 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D21 compound treatment 372480.0 -143000.0 -1.21 375770.0 -146000.0 -1.24 -1.7316 -1.0 2143393 PK04_098081 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D22 compound treatment 518790.0 3770.0 0.03 346620.0 -175000.0 -1.48 -1.0263 -0.6917 2065844 PK04_098082 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D23 compound treatment 434300.0 -80700.0 -0.69 484440.0 -37100.0 -0.31 -0.7079 -0.9373 2144185 PK04_098083 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 D24 compound treatment 399520.0 -116000.0 -0.98 497790.0 -23700.0 -0.2 -0.8371 -0.8346 2141197 PK04_098084 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E01 mock treatment 552960.0 37900.0 0.32 532480.0 11000.0 0.09 0.294 0.8753 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E02 mock treatment 518820.0 3800.0 0.03 552850.0 31300.0 0.27 0.2108 0.7873 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E03 compound treatment 425890.0 -89100.0 -0.76 369990.0 -152000.0 -1.29 -1.445 -0.9683 2141526 PK04_098085 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccc(C#CCCO)cc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E04 compound treatment 536000.0 21000.0 0.18 340980.0 -181000.0 -1.53 -0.9566 -0.6205 2142637 PK04_098086 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E05 compound treatment 525360.0 10300.0 0.09 461480.0 -60000.0 -0.51 -0.2979 -0.5764 2141181 PK04_098087 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(OCCO)cc5)[C@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E06 compound treatment 339950.0 -175000.0 -1.49 340750.0 -181000.0 -1.53 -2.1374 -0.9999 2142777 PK04_098088 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E07 compound treatment 518320.0 3300.0 0.03 475290.0 -46200.0 -0.39 -0.2574 -0.6548 2141090 PK04_098089 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E08 compound treatment 423550.0 -91500.0 -0.78 399360.0 -122000.0 -1.04 -1.2829 -0.99 2144801 PK04_098090 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E09 mock treatment 517130.0 2110.0 0.02 560800.0 39300.0 0.33 0.2484 0.7441 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E10 mock treatment 565390.0 50400.0 0.43 564060.0 42600.0 0.36 0.5582 0.9964 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E11 compound treatment 437790.0 -77200.0 -0.66 453080.0 -68400.0 -0.58 -0.875 -0.9981 2141328 PK04_098091 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)N9CCCCCCC9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E12 compound treatment 200530.0 -314000.0 -2.68 213280.0 -308000.0 -2.61 -3.7407 -0.9999 2144117 PK04_098092 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E13 compound treatment 336640.0 -178000.0 -1.52 298400.0 -223000.0 -1.89 -2.4113 -0.994 2141750 PK04_098093 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8=CCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E14 compound treatment 474560.0 -40500.0 -0.34 492320.0 -29200.0 -0.25 -0.4185 -0.9869 2142133 PK04_098094 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E15 compound treatment 375770.0 -139000.0 -1.18 436040.0 -85500.0 -0.73 -1.3503 -0.9722 2141837 PK04_098095 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E16 compound treatment 509820.0 -5200.0 -0.04 503450.0 -18100.0 -0.15 -0.1396 -0.8756 2143333 PK04_098096 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E17 mock treatment 565480.0 50500.0 0.43 529840.0 8330.0 0.07 0.3535 0.8126 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E18 mock treatment 535130.0 20100.0 0.17 549960.0 28500.0 0.24 0.2916 0.9858 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E19 compound treatment 267300.0 -248000.0 -2.11 373720.0 -148000.0 -1.25 -2.3766 -0.9692 2141392 PK04_098097 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E20 compound treatment 495610.0 -19400.0 -0.17 386450.0 -135000.0 -1.15 -0.9269 -0.8008 2144457 PK04_098098 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E21 compound treatment 528030.0 13000.0 0.11 448540.0 -73000.0 -0.62 -0.3594 -0.5716 2141783 PK04_098099 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E22 compound treatment 454560.0 -60500.0 -0.51 476480.0 -45000.0 -0.38 -0.6338 -0.9893 2142073 PK04_098100 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E23 compound treatment 365600.0 -149000.0 -1.27 372960.0 -149000.0 -1.26 -1.7899 -1.0 2141929 PK04_098101 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccccc5OCCO)[C@@]36C(=O)Nc7ccccc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 E24 compound treatment 415140.0 -99900.0 -0.85 536870.0 15400.0 0.13 -0.5087 -0.5917 2141993 PK04_098102 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F01 mock treatment 545760.0 30700.0 0.26 494720.0 -26800.0 -0.23 0.0242 0.0699 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F02 mock treatment 494740.0 -20300.0 -0.17 522640.0 1130.0 0.01 -0.1152 -0.6667 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F03 compound treatment 440860.0 -74200.0 -0.63 463840.0 -57700.0 -0.49 -0.792 -0.9921 2142917 PK04_098103 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F04 compound treatment 548000.0 33000.0 0.28 201380.0 -320000.0 -2.72 -1.7218 -0.6307 2142953 PK04_098104 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F05 compound treatment 239450.0 -276000.0 -2.34 410560.0 -111000.0 -0.94 -2.3232 -0.9196 2144897 PK04_098105 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F06 compound treatment 542210.0 27200.0 0.23 462400.0 -59100.0 -0.5 -0.191 -0.3459 2144329 PK04_098106 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F07 compound treatment 411640.0 -103000.0 -0.88 222780.0 -299000.0 -2.53 -2.4137 -0.8999 2144721 PK04_098107 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F08 compound treatment 309930.0 -205000.0 -1.74 273480.0 -248000.0 -2.1 -2.7215 -0.9957 2143969 PK04_098108 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F09 mock treatment 563850.0 48800.0 0.42 524210.0 2700.0 0.02 0.3099 0.745 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F10 mock treatment 562080.0 47100.0 0.4 409720.0 -112000.0 -0.95 -0.3874 -0.3764 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F11 compound treatment 456390.0 -58600.0 -0.5 374020.0 -147000.0 -1.25 -1.2374 -0.9187 2141973 PK04_098109 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F12 compound treatment 352880.0 -162000.0 -1.38 243010.0 -278000.0 -2.36 -2.6459 -0.9672 2141515 PK04_098110 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(OCCO)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F13 compound treatment 359120.0 -156000.0 -1.33 320700.0 -201000.0 -1.7 -2.1423 -0.9923 2144053 PK04_098111 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F14 compound treatment 396680.0 -118000.0 -1.01 456240.0 -65300.0 -0.55 -1.1034 -0.9603 2143249 PK04_098112 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F15 compound treatment 262480.0 -253000.0 -2.15 245010.0 -276000.0 -2.35 -3.1777 -0.999 2144873 PK04_098113 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F16 compound treatment 484410.0 -30600.0 -0.26 320800.0 -201000.0 -1.7 -1.388 -0.8059 2141199 PK04_098114 NC(=O)[C@H]1[C@H]2N([C@@H](c3ccc(OCCO)cc3)[C@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@@H]([C@@H](OC2=O)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F17 mock treatment 522880.0 7860.0 0.07 572320.0 50800.0 0.43 0.3521 0.8071 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F18 mock treatment 553570.0 38500.0 0.33 505960.0 -15500.0 -0.13 0.1386 0.3922 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F19 compound treatment 270080.0 -245000.0 -2.08 204320.0 -317000.0 -2.69 -3.376 -0.992 2142825 PK04_098115 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F20 compound treatment 516550.0 1530.0 0.01 414640.0 -107000.0 -0.91 -0.6318 -0.6969 2144217 PK04_098116 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F21 compound treatment 338080.0 -177000.0 -1.51 360350.0 -161000.0 -1.37 -2.0311 -0.9988 2144057 PK04_098117 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F22 compound treatment 488750.0 -26300.0 -0.22 484480.0 -37000.0 -0.31 -0.3801 -0.9861 2141689 PK04_098118 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F23 compound treatment 205310.0 -310000.0 -2.63 185440.0 -336000.0 -2.85 -3.8789 -0.9992 2144037 PK04_098119 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 F24 compound treatment 466740.0 -48300.0 -0.41 527270.0 5760.0 0.05 -0.2559 -0.6186 2141464 PK04_098120 Oc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)Nc4nc5ccccc5s4)[C@@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@H]([C@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G01 compound treatment 116170.0 -399000.0 -3.39 168480.0 -353000.0 -2.99 -4.5168 -0.9981 2141573 PK04_098121 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(OCCO)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G02 compound treatment 258680.0 -256000.0 -2.18 315240.0 -206000.0 -1.75 -2.7793 -0.994 2144113 PK04_098122 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G03 mock treatment 559420.0 44400.0 0.38 464400.0 -57100.0 -0.48 -0.0755 -0.1228 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G04 mock treatment 540770.0 25700.0 0.22 509050.0 -12500.0 -0.11 0.0802 0.3296 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G05 compound treatment 282450.0 -233000.0 -1.98 417120.0 -104000.0 -0.89 -2.0252 -0.9343 2141531 PK04_098123 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G06 compound treatment 141620.0 -373000.0 -3.18 85620.0 -436000.0 -3.7 -4.8608 -0.9971 2143985 PK04_098124 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G07 compound treatment 300690.0 -214000.0 -1.82 273220.0 -248000.0 -2.11 -2.7786 -0.9974 2065843 PK04_098125 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G08 compound treatment 265280.0 -250000.0 -2.12 292830.0 -229000.0 -1.94 -2.874 -0.999 2144713 PK04_098126 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7ccccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G09 compound treatment 528190.0 13200.0 0.11 581150.0 59600.0 0.51 0.437 0.8433 2141779 PK04_098127 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G10 compound treatment 433720.0 -81300.0 -0.69 502610.0 -18900.0 -0.16 -0.6024 -0.8485 2142633 PK04_098128 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G11 compound treatment 24360.0 -491000.0 -4.17 37040.0 -484000.0 -4.11 -5.8575 -1.0 2141711 PK04_098129 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G12 compound treatment 301930.0 -213000.0 -1.81 454430.0 -67100.0 -0.57 -1.6842 -0.8864 2142689 PK04_098130 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G13 compound treatment 324580.0 -190000.0 -1.62 571570.0 50100.0 0.42 -0.8453 -0.5047 2141802 PK04_098131 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G14 compound treatment 438910.0 -76100.0 -0.65 431850.0 -89700.0 -0.76 -0.9956 -0.9968 2142905 PK04_098132 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G15 compound treatment 527390.0 12400.0 0.11 421540.0 -100000.0 -0.85 -0.5252 -0.6146 2141192 PK04_098133 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCc9cc(OC)c(OC)cc9C8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G16 compound treatment 174790.0 -340000.0 -2.89 421410.0 -100000.0 -0.85 -2.6471 -0.8776 2142129 PK04_098134 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G17 compound treatment 296030.0 -219000.0 -1.86 313570.0 -208000.0 -1.76 -2.5646 -0.9996 2141728 PK04_098135 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CC8(O)CCCCCC8)cc76)C(=O)O[C@@H]([C@@H]3c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G18 compound treatment 437540.0 -77500.0 -0.66 335300.0 -186000.0 -1.58 -1.583 -0.9249 2144641 PK04_098136 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G19 mock treatment 508560.0 -6460.0 -0.05 595010.0 73500.0 0.62 0.402 0.6423 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G20 mock treatment 567520.0 52500.0 0.45 542300.0 20800.0 0.18 0.4405 0.9174 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G21 compound treatment 321840.0 -193000.0 -1.64 284480.0 -237000.0 -2.01 -2.5838 -0.995 2141885 PK04_098137 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G22 compound treatment 482430.0 -32600.0 -0.28 555150.0 33600.0 0.29 0.0057 0.0144 2144357 PK04_098138 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G23 compound treatment 500520.0 -14500.0 -0.12 449760.0 -71700.0 -0.61 -0.5176 -0.8335 2141361 PK04_098139 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccccc5OCCO)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCCCCCC8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 G24 compound treatment 389760.0 -125000.0 -1.07 544750.0 23200.0 0.2 -0.6141 -0.5667 2142625 PK04_098140 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H01 compound treatment 333760.0 -181000.0 -1.54 343740.0 -178000.0 -1.51 -2.1567 -0.9999 2142737 PK04_098141 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H02 compound treatment 318730.0 -196000.0 -1.67 234720.0 -287000.0 -2.43 -2.901 -0.9831 2144017 PK04_098142 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H03 mock treatment 591360.0 76300.0 0.65 496960.0 -24500.0 -0.21 0.312 0.4574 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H04 mock treatment 454330.0 -60700.0 -0.52 380340.0 -141000.0 -1.2 -1.2118 -0.9293 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H05 compound treatment 378880.0 -136000.0 -1.16 276180.0 -245000.0 -2.08 -2.2905 -0.9617 2143493 PK04_098143 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H06 compound treatment 466880.0 -48100.0 -0.41 510830.0 -10700.0 -0.09 -0.3536 -0.8431 2141857 PK04_098144 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccccc65)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H07 compound treatment 450560.0 -64500.0 -0.55 331540.0 -190000.0 -1.61 -1.5272 -0.8972 2143497 PK04_098145 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H08 compound treatment 521650.0 6630.0 0.06 518590.0 -2920.0 -0.02 0.0224 0.3633 2141183 PK04_098146 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(OCCO)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NCC=C)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H09 compound treatment 272050.0 -243000.0 -2.07 550250.0 28700.0 0.24 -1.2892 -0.6194 2143289 PK04_098147 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H10 compound treatment 405240.0 -110000.0 -0.93 282040.0 -239000.0 -2.03 -2.0968 -0.9378 2142033 PK04_098148 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H11 compound treatment 312340.0 -203000.0 -1.72 436700.0 -84800.0 -0.72 -1.7279 -0.9249 2143345 PK04_098149 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H12 compound treatment 333680.0 -181000.0 -1.54 278800.0 -243000.0 -2.06 -2.5467 -0.9899 2141965 PK04_098150 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H13 compound treatment 572910.0 57900.0 0.49 507580.0 -13900.0 -0.12 0.2647 0.5226 2142053 PK04_098151 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H14 compound treatment 416680.0 -98300.0 -0.84 568190.0 46700.0 0.4 -0.3116 -0.3366 2143285 PK04_098152 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H15 compound treatment 364330.0 -151000.0 -1.28 355600.0 -166000.0 -1.41 -1.9016 -0.9989 2143953 PK04_098153 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H16 compound treatment 373410.0 -142000.0 -1.2 293390.0 -228000.0 -1.94 -2.2202 -0.974 2142849 PK04_098154 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H17 compound treatment 473630.0 -41400.0 -0.35 363840.0 -158000.0 -1.34 -1.1947 -0.8638 2142197 PK04_098155 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H18 compound treatment 313940.0 -201000.0 -1.71 355530.0 -166000.0 -1.41 -2.2052 -0.9953 2141678 PK04_098156 COc1ccc(C#Cc2ccc3NC(=O)[C@]4([C@@H]([C@@H]5N([C@@H]4c6ccccc6OCCO)[C@H]([C@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)NCC=C)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H19 mock treatment 542040.0 27000.0 0.23 554900.0 33400.0 0.28 0.3628 0.9946 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H20 mock treatment 521450.0 6430.0 0.05 499260.0 -22200.0 -0.19 -0.0948 -0.4823 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H21 compound treatment 436850.0 -78200.0 -0.67 493320.0 -28200.0 -0.24 -0.6393 -0.9047 2142657 PK04_098157 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H22 compound treatment 266530.0 -248000.0 -2.11 326340.0 -195000.0 -1.66 -2.6655 -0.9927 2141194 PK04_098158 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NCC=C)[C@@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@H]([C@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H23 compound treatment 386440.0 -129000.0 -1.09 302490.0 -219000.0 -1.86 -2.0872 -0.9681 2142665 PK04_098159 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 H24 compound treatment 508770.0 -6250.0 -0.05 507970.0 -13500.0 -0.11 -0.1188 -0.9388 2141813 PK04_098160 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I01 compound treatment 225650.0 -289000.0 -2.46 147750.0 -374000.0 -3.17 -3.9826 -0.9922 2141395 PK04_098161 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I02 compound treatment 369150.0 -146000.0 -1.24 213520.0 -308000.0 -2.61 -2.7249 -0.9421 2144813 PK04_098162 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I03 compound treatment 295760.0 -219000.0 -1.87 161930.0 -360000.0 -3.05 -3.4758 -0.9722 2141107 PK04_098163 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)O)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I04 compound treatment 297520.0 -218000.0 -1.85 319950.0 -202000.0 -1.71 -2.5174 -0.9992 2142597 PK04_098164 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I05 mock treatment 567650.0 52600.0 0.45 584770.0 63300.0 0.54 0.6961 0.9959 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I06 mock treatment 459430.0 -55600.0 -0.47 470830.0 -50700.0 -0.43 -0.6384 -0.9989 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I07 compound treatment 590600.0 75600.0 0.64 514820.0 -6690.0 -0.06 0.4145 0.6422 2141144 PK04_098165 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I08 compound treatment 470400.0 -44600.0 -0.38 432160.0 -89300.0 -0.76 -0.8043 -0.9489 2142693 PK04_098166 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I09 compound treatment 517560.0 2540.0 0.02 442400.0 -79100.0 -0.67 -0.4592 -0.684 2141896 PK04_098167 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccccc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I10 compound treatment 389570.0 -125000.0 -1.07 501440.0 -20100.0 -0.17 -0.875 -0.8097 2141957 PK04_098168 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I11 compound treatment 472580.0 -42400.0 -0.36 404880.0 -117000.0 -0.99 -0.9549 -0.9067 2141394 PK04_098169 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I12 compound treatment 248000.0 -267000.0 -2.27 381440.0 -140000.0 -1.19 -2.4464 -0.9543 2142049 PK04_098170 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I13 compound treatment 390730.0 -124000.0 -1.06 528510.0 7000.0 0.06 -0.7057 -0.6663 2141346 PK04_098171 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccccc5OCCO)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I14 compound treatment 346130.0 -169000.0 -1.44 306040.0 -215000.0 -1.83 -2.3084 -0.9929 2143477 PK04_098172 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I15 compound treatment 137860.0 -377000.0 -3.21 192960.0 -329000.0 -2.79 -4.2395 -0.9975 2141373 PK04_098173 OCCOc1ccccc1[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I16 compound treatment 337220.0 -178000.0 -1.51 452490.0 -69000.0 -0.59 -1.4836 -0.9147 2144645 PK04_098174 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8ccccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I17 compound treatment 568050.0 53000.0 0.45 567860.0 46400.0 0.39 0.597 0.9977 2141116 PK04_098175 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I18 compound treatment 298360.0 -217000.0 -1.84 294290.0 -227000.0 -1.93 -2.6662 -0.9998 2142097 PK04_098176 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I19 compound treatment 499960.0 -15100.0 -0.13 547490.0 26000.0 0.22 0.0652 0.2559 2141442 PK04_098177 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)Nc8nc9ccccc9s8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I20 compound treatment 546430.0 31400.0 0.27 572550.0 51000.0 0.43 0.4951 0.9731 2142005 PK04_098178 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I21 mock treatment 563490.0 48500.0 0.41 546050.0 24500.0 0.21 0.4388 0.9499 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I22 mock treatment 541650.0 26600.0 0.23 478980.0 -42500.0 -0.36 -0.0949 -0.2228 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I23 compound treatment 382080.0 -133000.0 -1.13 398190.0 -123000.0 -1.05 -1.5394 -0.9992 2141137 PK04_098179 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 I24 compound treatment 328030.0 -187000.0 -1.59 384220.0 -137000.0 -1.16 -1.9483 -0.9882 2144905 PK04_098180 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J01 compound treatment 246030.0 -269000.0 -2.29 237390.0 -284000.0 -2.41 -3.3223 -0.9997 2142853 PK04_098181 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J02 compound treatment 426650.0 -88400.0 -0.75 440800.0 -80700.0 -0.68 -1.0157 -0.9989 2141434 PK04_098182 COc1cc2CCN(Cc2cc1OC)C(=O)[C@H]3[C@H]4N([C@@H](c5ccc(O)cc5)[C@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@@H]([C@@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J03 compound treatment 403920.0 -111000.0 -0.95 217860.0 -304000.0 -2.58 -2.4897 -0.9074 2142925 PK04_098183 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#Cc8ccc(OC)cc8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J04 compound treatment 524030.0 9010.0 0.08 393790.0 -128000.0 -1.08 -0.7119 -0.6554 2141810 PK04_098184 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CC6(O)CCCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J05 mock treatment 396800.0 -118000.0 -1.01 527940.0 6430.0 0.05 -0.6726 -0.6678 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J06 mock treatment 579220.0 64200.0 0.55 316760.0 -205000.0 -1.74 -0.8419 -0.4624 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J07 compound treatment 435360.0 -79700.0 -0.68 301700.0 -220000.0 -1.86 -1.7977 -0.9061 2143253 PK04_098185 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J08 compound treatment 284960.0 -230000.0 -1.96 209310.0 -312000.0 -2.65 -3.2566 -0.9889 2141219 PK04_098186 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)NC[C@H](O)c4ccccc4)[C@@]25C(=O)Nc6ccc(C#CC7=CCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J09 compound treatment 419700.0 -95300.0 -0.81 306720.0 -215000.0 -1.82 -1.8617 -0.9335 2142945 PK04_098187 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J10 compound treatment 477810.0 -37200.0 -0.32 606160.0 84700.0 0.72 0.2839 0.3618 2141450 PK04_098188 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J11 compound treatment 528430.0 13400.0 0.11 577030.0 55500.0 0.47 0.4137 0.8537 2144285 PK04_098189 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J12 compound treatment 263680.0 -251000.0 -2.14 208720.0 -313000.0 -2.65 -3.3881 -0.9943 2141139 PK04_098190 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)O)[C@]24C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J13 compound treatment 442740.0 -72300.0 -0.61 295860.0 -226000.0 -1.91 -1.7883 -0.8895 2143473 PK04_098191 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J14 compound treatment 354030.0 -161000.0 -1.37 393770.0 -128000.0 -1.08 -1.7346 -0.9933 2144013 PK04_098192 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J15 compound treatment 146720.0 -368000.0 -3.13 312700.0 -209000.0 -1.77 -3.468 -0.9635 2142837 PK04_098193 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CC9=CCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J16 compound treatment 449760.0 -65300.0 -0.56 471840.0 -49700.0 -0.42 -0.6905 -0.9907 2141784 PK04_098194 NC(=O)NCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N8CCN(CC8)c9ncccn9)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J17 compound treatment 344830.0 -170000.0 -1.45 347520.0 -174000.0 -1.48 -2.0674 -1.0 2144425 PK04_098195 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J18 compound treatment 275080.0 -240000.0 -2.04 304960.0 -217000.0 -1.84 -2.7423 -0.9986 2141332 PK04_098196 COc1ccc(C#Cc2ccc3NC(=O)[C@@]4([C@H]([C@H]5N([C@H]4c6ccccc6OCCO)[C@@H]([C@@H](OC5=O)c7ccccc7)c8ccccc8)C(=O)Nc9nc%10ccccc%10s9)c3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J19 compound treatment 300650.0 -214000.0 -1.82 351960.0 -170000.0 -1.44 -2.3065 -0.9931 2143957 PK04_098197 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J20 compound treatment 587110.0 72100.0 0.61 615330.0 93800.0 0.8 0.9964 0.9917 2141933 PK04_098198 Oc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)N4CCCCCCC4)[C@]25C(=O)Nc6ccccc65)C(=O)O[C@@H]([C@@H]3c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J21 mock treatment 352040.0 -163000.0 -1.39 584560.0 63100.0 0.53 -0.6022 -0.4052 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J22 mock treatment 558190.0 43200.0 0.37 570780.0 49300.0 0.42 0.5552 0.9979 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J23 compound treatment 326880.0 -188000.0 -1.6 389010.0 -132000.0 -1.12 -1.9265 -0.985 2144049 PK04_098199 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 J24 compound treatment 424920.0 -90100.0 -0.77 421720.0 -99800.0 -0.85 -1.1406 -0.9988 2141196 PK04_098200 OCCOc1ccc(cc1)[C@@H]2N3[C@H]([C@H](C(=O)N4CCCCCCC4)[C@@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@H]([C@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K01 compound treatment 482890.0 -32100.0 -0.27 443200.0 -78300.0 -0.66 -0.663 -0.923 2141522 PK04_098201 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(OCCO)cc5)[C@@]36C(=O)Nc7ccc(C#CCNC(=O)N)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K02 compound treatment 541320.0 26300.0 0.22 396160.0 -125000.0 -1.06 -0.5937 -0.5464 2142617 PK04_098202 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K03 compound treatment 568400.0 53400.0 0.45 579050.0 57500.0 0.49 0.6663 0.9993 2141439 PK04_098203 OCCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K04 compound treatment 459310.0 -55700.0 -0.47 282880.0 -239000.0 -2.02 -1.7665 -0.8497 2143329 PK04_098204 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K05 compound treatment 191320.0 -324000.0 -2.75 167360.0 -354000.0 -3.0 -4.0715 -0.9991 2141725 PK04_098205 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NC[C@H](O)c4ccccc4)[C@]25C(=O)Nc6ccc(C#CC7(O)CCCCCC7)cc65)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K06 compound treatment 368530.0 -146000.0 -1.25 322560.0 -199000.0 -1.69 -2.0746 -0.9889 2142973 PK04_098206 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K07 mock treatment 567760.0 52700.0 0.45 541120.0 19600.0 0.17 0.4349 0.9088 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K08 mock treatment 585730.0 70700.0 0.6 475680.0 -45800.0 -0.39 0.1505 0.2101 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K09 compound treatment 207880.0 -307000.0 -2.61 356590.0 -165000.0 -1.4 -2.8368 -0.9571 2141136 PK04_098207 COC(=O)C(CC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccccc5OCCO)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K10 compound treatment 572020.0 57000.0 0.48 615520.0 94000.0 0.8 0.9068 0.9716 2143005 PK04_098208 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K11 compound treatment 235610.0 -279000.0 -2.38 242610.0 -279000.0 -2.37 -3.3537 -1.0 2141925 PK04_098209 NC(=O)[C@@H]1[C@@H]2N([C@H](c3ccccc3OCCO)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K12 compound treatment 408570.0 -106000.0 -0.91 435770.0 -85700.0 -0.73 -1.1546 -0.9941 2144741 PK04_098210 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K13 compound treatment 266330.0 -249000.0 -2.12 391070.0 -130000.0 -1.11 -2.2784 -0.9543 2141147 PK04_098211 OC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccc(C#CC6=CCCCC6)cc54)[C@H]([C@H](OC2=O)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K14 compound treatment 535840.0 20800.0 0.18 413450.0 -108000.0 -0.92 -0.5229 -0.5601 2143465 PK04_098212 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K15 mock treatment 377440.0 -138000.0 -1.17 554500.0 33000.0 0.28 -0.6297 -0.5233 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K16 mock treatment 627840.0 113000.0 0.96 535010.0 13500.0 0.11 0.7597 0.7859 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K17 compound treatment 593040.0 78000.0 0.66 497540.0 -24000.0 -0.2 0.3256 0.469 2141530 PK04_098213 OCCOc1ccc(cc1)[C@H]2N3[C@@H]([C@@H](C(=O)Nc4nc5ccccc5s4)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K18 compound treatment 509780.0 -5240.0 -0.04 548550.0 27000.0 0.23 0.1307 0.5592 2143169 PK04_098214 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K19 compound treatment 367380.0 -148000.0 -1.26 448570.0 -72900.0 -0.62 -1.3256 -0.9468 2141707 PK04_098215 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)N4CCN(CC4)c5ncccn5)[C@]26C(=O)Nc7ccc(C#CCCO)cc76)C(=O)O[C@@H]([C@@H]3c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K20 compound treatment 466510.0 -48500.0 -0.41 499150.0 -22400.0 -0.19 -0.4259 -0.9378 2143073 PK04_098216 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K21 compound treatment 597600.0 82600.0 0.7 537220.0 15700.0 0.13 0.591 0.8265 2141428 PK04_098217 NC(=O)NCC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)NC[C@H](O)c8ccccc8)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K22 compound treatment 241010.0 -274000.0 -2.33 262080.0 -259000.0 -2.2 -3.2044 -0.9996 2142725 PK04_098218 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K23 mock treatment 512530.0 -2490.0 -0.02 553080.0 31600.0 0.27 0.1744 0.6491 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 K24 mock treatment 481700.0 -33300.0 -0.28 534760.0 13300.0 0.11 -0.121 -0.3966 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L01 compound treatment 419310.0 -95700.0 -0.81 513070.0 -8440.0 -0.07 -0.6264 -0.7663 2143889 PK04_098219 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L02 compound treatment 305060.0 -210000.0 -1.79 456860.0 -64600.0 -0.55 -1.6508 -0.8835 2141700 PK04_098220 OCCOc1ccccc1[C@H]2N3[C@@H]([C@@H](C(=O)NCC=C)[C@]24C(=O)Nc5ccc(C#CCCO)cc54)C(=O)O[C@@H]([C@@H]3c6ccccc6)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L03 compound treatment 28040.0 -487000.0 -4.14 53030.0 -468000.0 -3.97 -5.7395 -0.9998 2142733 PK04_098221 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L04 compound treatment 480870.0 -34200.0 -0.29 436210.0 -85300.0 -0.72 -0.7171 -0.9197 2141934 PK04_098222 O[C@@H](CNC(=O)[C@@H]1[C@@H]2N([C@H](c3ccc(O)cc3)[C@@]14C(=O)Nc5ccccc54)[C@H]([C@H](OC2=O)c6ccccc6)c7ccccc7)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L05 compound treatment 388320.0 -127000.0 -1.08 508360.0 -13100.0 -0.11 -0.841 -0.7761 2143873 PK04_098223 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L06 compound treatment 474080.0 -40900.0 -0.35 468670.0 -52800.0 -0.45 -0.5632 -0.9922 2141797 PK04_098224 COc1cc2CCN(Cc2cc1OC)C(=O)[C@@H]3[C@@H]4N([C@H](c5ccc(O)cc5)[C@@]36C(=O)Nc7ccc(C#CCCO)cc76)[C@H]([C@H](OC4=O)c8ccccc8)c9ccccc9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L07 mock treatment 354880.0 -160000.0 -1.36 501520.0 -20000.0 -0.17 -1.0832 -0.789 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L08 mock treatment 538760.0 23700.0 0.2 567470.0 46000.0 0.39 0.4185 0.9531 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L09 compound treatment 488800.0 -26200.0 -0.22 349760.0 -172000.0 -1.46 -1.1879 -0.806 2142957 PK04_098225 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L10 compound treatment 468020.0 -47000.0 -0.4 626520.0 105000.0 0.89 0.3471 0.3555 3413983 PK04_098226 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L11 compound treatment 199600.0 -315000.0 -2.68 241860.0 -280000.0 -2.37 -3.5748 -0.9981 2142717 PK04_098227 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L12 compound treatment 550630.0 35600.0 0.3 308130.0 -213000.0 -1.81 -1.0657 -0.5807 3413985 PK04_098228 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L13 compound treatment 470530.0 -44500.0 -0.38 515400.0 -6110.0 -0.05 -0.3043 -0.7965 2143357 PK04_098229 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L14 compound treatment 495290.0 -19700.0 -0.17 526330.0 4820.0 0.04 -0.0898 -0.5196 3413987 PK04_098230 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L15 mock treatment 550640.0 35600.0 0.3 442720.0 -78800.0 -0.67 -0.2583 -0.352 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L16 mock treatment 497890.0 -17100.0 -0.15 485300.0 -36200.0 -0.31 -0.3202 -0.942 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L17 compound treatment 565060.0 50000.0 0.43 557480.0 36000.0 0.31 0.5168 0.9867 2143089 PK04_098231 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10(O)CCCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L18 compound treatment 533080.0 18100.0 0.15 326720.0 -195000.0 -1.65 -1.0597 -0.6386 3413990 PK04_098232 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L19 compound treatment 480750.0 -34300.0 -0.29 415090.0 -106000.0 -0.9 -0.8445 -0.8902 2144137 PK04_098233 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L20 compound treatment 526080.0 11100.0 0.09 548070.0 26600.0 0.23 0.2259 0.925 3413992 PK04_098234 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L21 compound treatment 492610.0 -22400.0 -0.19 423380.0 -98100.0 -0.83 -0.7234 -0.8471 2143369 PK04_098235 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L22 compound treatment 441440.0 -73600.0 -0.63 470590.0 -50900.0 -0.43 -0.748 -0.9836 3413998 PK04_098236 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@@H]4OC(=O)[C@H](Cc5cccc(Br)c5)C/C=C/C[C@@H](Cc6cccc(Br)c6)C(=O)O[C@@H]14 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L23 mock treatment 492160.0 -22900.0 -0.19 513120.0 -8390.0 -0.07 -0.1878 -0.907 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 L24 mock treatment 494830.0 -20200.0 -0.17 544990.0 23500.0 0.2 0.0194 0.0737 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M01 compound treatment 513880.0 -1140.0 -0.01 329200.0 -192000.0 -1.63 -1.1604 -0.7113 2141977 PK04_098237 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M02 compound treatment 533690.0 18700.0 0.16 560700.0 39200.0 0.33 0.3474 0.9428 2144277 PK04_098238 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M03 compound treatment 381280.0 -134000.0 -1.14 456810.0 -64700.0 -0.55 -1.1926 -0.9441 2143353 PK04_098239 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M04 compound treatment 320910.0 -194000.0 -1.65 298890.0 -223000.0 -1.89 -2.503 -0.9978 2142753 PK04_098240 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9(O)CCCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M05 compound treatment 194880.0 -320000.0 -2.72 255130.0 -266000.0 -2.26 -3.5236 -0.9957 2142713 PK04_098241 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M06 compound treatment 264100.0 -251000.0 -2.13 411560.0 -110000.0 -0.93 -2.1689 -0.9311 2143893 PK04_098242 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M07 compound treatment 246580.0 -268000.0 -2.28 427230.0 -94300.0 -0.8 -2.1803 -0.9011 2143173 PK04_098243 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M08 compound treatment 428660.0 -86400.0 -0.73 297360.0 -224000.0 -1.9 -1.864 -0.9144 2143913 PK04_098244 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M09 mock treatment 540550.0 25500.0 0.22 585760.0 64300.0 0.55 0.539 0.9186 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M10 mock treatment 506290.0 -8730.0 -0.07 571520.0 50000.0 0.42 0.2475 0.5746 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M11 compound treatment 272240.0 -243000.0 -2.07 195410.0 -326000.0 -2.77 -3.4165 -0.9896 2143965 PK04_098245 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCCO)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M12 compound treatment 380430.0 -135000.0 -1.15 242240.0 -279000.0 -2.37 -2.4847 -0.9444 2144453 PK04_098246 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M13 mock treatment 267200.0 -248000.0 -2.11 534470.0 13000.0 0.11 -1.413 -0.6693 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M14 mock treatment 600500.0 85500.0 0.73 595170.0 73700.0 0.62 0.956 0.9971 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M15 compound treatment 452320.0 -62700.0 -0.53 572640.0 51100.0 0.43 -0.0705 -0.1025 2142065 PK04_098247 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M16 compound treatment 513620.0 -1400.0 -0.01 564450.0 42900.0 0.36 0.2491 0.6836 2143293 PK04_098248 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M17 compound treatment 307480.0 -208000.0 -1.77 345670.0 -176000.0 -1.49 -2.3032 -0.9965 2142857 PK04_098249 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M18 compound treatment 565760.0 50700.0 0.43 520340.0 -1170.0 -0.01 0.2982 0.6907 2142613 PK04_098250 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M19 compound treatment 400360.0 -115000.0 -0.98 480160.0 -41300.0 -0.35 -0.9378 -0.9047 2142697 PK04_098251 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M20 compound treatment 439120.0 -75900.0 -0.65 557120.0 35600.0 0.3 -0.243 -0.3408 2144821 PK04_098252 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M21 compound treatment 597080.0 82100.0 0.7 525540.0 4030.0 0.03 0.5178 0.7409 2142965 PK04_098253 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M22 compound treatment 445640.0 -69400.0 -0.59 517820.0 -3690.0 -0.03 -0.4395 -0.7435 2144777 PK04_098254 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M23 compound treatment 579410.0 64400.0 0.55 510960.0 -10500.0 -0.09 0.3241 0.5839 2141143 PK04_098255 OCCC#Cc1ccc2NC(=O)[C@]3([C@@H]([C@@H]4N([C@@H]3c5ccc(O)cc5)[C@H]([C@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)O)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 M24 compound treatment 400710.0 -114000.0 -0.97 508170.0 -13300.0 -0.11 -0.7676 -0.7841 2144937 PK04_098256 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N01 compound treatment 429340.0 -85700.0 -0.73 452180.0 -69300.0 -0.59 -0.9313 -0.9943 2144901 PK04_098257 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N02 compound treatment 401780.0 -113000.0 -0.96 447170.0 -74300.0 -0.63 -1.1271 -0.9789 3413999 PK04_098258 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N03 compound treatment 406720.0 -108000.0 -0.92 397960.0 -124000.0 -1.05 -1.3926 -0.9979 2143297 PK04_098259 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N04 compound treatment 321890.0 -193000.0 -1.64 295060.0 -226000.0 -1.92 -2.5201 -0.997 3414005 PK04_098260 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@@H]3OC(=O)[C@H](Cc4cccc(Br)c4)C/C=C/C[C@@H](Cc5cccc(Br)c5)C(=O)O[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N05 compound treatment 448640.0 -66400.0 -0.56 492910.0 -28600.0 -0.24 -0.5709 -0.9288 2142017 PK04_098261 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N06 compound treatment 554560.0 39500.0 0.34 547040.0 25500.0 0.22 0.391 0.9773 3188747 PK04_098262 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)CCc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N07 compound treatment 510040.0 -4980.0 -0.04 466770.0 -54700.0 -0.46 -0.3583 -0.7684 2143017 PK04_098263 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N08 compound treatment 492970.0 -22100.0 -0.19 286950.0 -235000.0 -1.99 -1.5396 -0.7704 3188748 PK04_098264 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N09 mock treatment 550100.0 35100.0 0.3 587390.0 65900.0 0.56 0.6062 0.9568 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N10 mock treatment 546170.0 31100.0 0.26 600520.0 79000.0 0.67 0.6613 0.9176 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N11 compound treatment 495520.0 -19500.0 -0.17 523770.0 2260.0 0.02 -0.1037 -0.6212 2144265 PK04_098265 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N12 compound treatment 449870.0 -65200.0 -0.55 498450.0 -23100.0 -0.2 -0.5302 -0.9021 3069249 PK04_098266 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)c3c(OC)cccc3OC)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N13 mock treatment 337450.0 -178000.0 -1.51 525470.0 3960.0 0.03 -1.0444 -0.6912 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N14 mock treatment 619910.0 105000.0 0.89 577720.0 56200.0 0.48 0.9681 0.9569 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N15 compound treatment 481050.0 -34000.0 -0.29 398160.0 -123000.0 -1.05 -0.9442 -0.8698 2143165 PK04_098267 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N16 compound treatment 519650.0 4630.0 0.04 424720.0 -96800.0 -0.82 -0.5527 -0.6724 3188751 PK04_098268 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccccc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N17 compound treatment 575330.0 60300.0 0.51 469010.0 -52500.0 -0.45 0.0479 0.0705 2144365 PK04_098269 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N18 compound treatment 403960.0 -111000.0 -0.94 369730.0 -152000.0 -1.29 -1.5785 -0.9884 3188752 PK04_098270 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3cccc(F)c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N19 compound treatment 365610.0 -149000.0 -1.27 400880.0 -121000.0 -1.02 -1.6223 -0.9942 2142105 PK04_098271 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N20 compound treatment 439520.0 -75500.0 -0.64 462120.0 -59400.0 -0.5 -0.8104 -0.9928 3068687 PK04_098272 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(OC)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N21 compound treatment 357780.0 -157000.0 -1.34 505330.0 -16200.0 -0.14 -1.0429 -0.7756 2144245 PK04_098273 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCNC(=O)N)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N22 compound treatment 347130.0 -168000.0 -1.43 299200.0 -222000.0 -1.89 -2.3434 -0.9906 3068689 PK04_098274 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc4OCOc4c3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N23 compound treatment 457120.0 -57900.0 -0.49 505160.0 -16300.0 -0.14 -0.4464 -0.8723 2143153 PK04_098275 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CC9=CCCCC9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 N24 compound treatment 282530.0 -232000.0 -1.98 328510.0 -193000.0 -1.64 -2.5562 -0.9956 3188876 PK04_098276 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(Br)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O01 compound treatment 315710.0 -199000.0 -1.7 425440.0 -96100.0 -0.81 -1.7752 -0.9436 2143373 PK04_098277 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCC(C(=O)OC)C(=O)OC)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O02 compound treatment 428800.0 -86200.0 -0.73 424660.0 -96800.0 -0.82 -1.0996 -0.9984 2142209 PK04_098278 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CC%10=CCCCC%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O03 compound treatment 425150.0 -89900.0 -0.76 415100.0 -106000.0 -0.9 -1.1789 -0.9966 2144345 PK04_098279 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8(O)CCCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O04 compound treatment 290560.0 -224000.0 -1.91 383640.0 -138000.0 -1.17 -2.1772 -0.9723 2142673 PK04_098280 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCCO)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O05 compound treatment 433600.0 -81400.0 -0.69 367870.0 -154000.0 -1.3 -1.4113 -0.9563 2143977 PK04_098281 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O06 compound treatment 367590.0 -147000.0 -1.25 546630.0 25100.0 0.21 -0.7362 -0.5787 2142077 PK04_098282 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O07 compound treatment 382400.0 -133000.0 -1.13 269690.0 -252000.0 -2.14 -2.3082 -0.9555 2141985 PK04_098283 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O08 compound treatment 170820.0 -344000.0 -2.93 225360.0 -296000.0 -2.51 -3.8469 -0.9971 2143485 PK04_098284 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CC8=CCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O09 compound treatment 422680.0 -92300.0 -0.79 401810.0 -120000.0 -1.02 -1.2735 -0.992 2144665 PK04_098285 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O10 compound treatment 353150.0 -162000.0 -1.38 462170.0 -59300.0 -0.5 -1.3297 -0.9069 2143273 PK04_098286 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#CCNC(=O)N)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O11 mock treatment 378310.0 -137000.0 -1.16 526020.0 4510.0 0.04 -0.7953 -0.6835 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O12 mock treatment 437450.0 -77600.0 -0.66 336000.0 -186000.0 -1.57 -1.5793 -0.9256 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O13 compound treatment 518510.0 3490.0 0.03 569700.0 48200.0 0.41 0.3101 0.7565 2144773 PK04_098287 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7ccccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O14 compound treatment 336070.0 -179000.0 -1.52 356060.0 -165000.0 -1.4 -2.0689 -0.9992 2143945 PK04_098288 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCCO)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O15 compound treatment 550900.0 35900.0 0.31 512160.0 -9350.0 -0.08 0.1598 0.5066 2144317 PK04_098289 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCC(C(=O)OC)C(=O)OC)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O16 compound treatment 403100.0 -112000.0 -0.95 248340.0 -273000.0 -2.32 -2.3118 -0.9228 2143905 PK04_098290 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O17 compound treatment 515910.0 889.0 0.01 441830.0 -79700.0 -0.68 -0.4726 -0.6991 2143917 PK04_098291 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCNC(=O)N)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O18 compound treatment 356540.0 -158000.0 -1.35 426120.0 -95400.0 -0.81 -1.5255 -0.9702 2144253 PK04_098292 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O19 compound treatment 366330.0 -149000.0 -1.26 403430.0 -118000.0 -1.0 -1.6027 -0.9933 2144105 PK04_098293 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CC8=CCCCC8)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O20 compound treatment 323140.0 -192000.0 -1.63 435890.0 -85600.0 -0.73 -1.6678 -0.9335 2144293 PK04_098294 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O21 compound treatment 376840.0 -138000.0 -1.18 513880.0 -7630.0 -0.06 -0.877 -0.7449 2142997 PK04_098295 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O22 compound treatment 264200.0 -251000.0 -2.13 345500.0 -176000.0 -1.49 -2.5646 -0.9847 2144737 PK04_098296 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O23 compound treatment 469300.0 -45700.0 -0.39 441920.0 -79600.0 -0.68 -0.7524 -0.9657 2141452 PK04_098297 COC(=O)C(CC#Cc1ccc2NC(=O)[C@@]3([C@H]([C@H]4N([C@H]3c5ccc(O)cc5)[C@@H]([C@@H](OC4=O)c6ccccc6)c7ccccc7)C(=O)N)c2c1)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 O24 compound treatment 313600.0 -201000.0 -1.71 210760.0 -311000.0 -2.64 -3.0756 -0.9782 2142677 PK04_098298 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NC[C@H](O)c7ccccc7)c8cc(C#CCCO)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P01 compound treatment 211650.0 -303000.0 -2.58 96160.0 -425000.0 -3.61 -4.3763 -0.9865 2144005 PK04_098299 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N)c7cc(C#CCC(C(=O)OC)C(=O)OC)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P02 compound treatment 86240.0 -429000.0 -3.65 78820.0 -443000.0 -3.76 -5.2347 -0.9999 3068772 PK04_098300 CCOC(=O)[C@H]1C/C=C/C[C@H](C(=O)OCC)C(=O)O[C@H]2[C@H](OC(=O)Nc3ccc(C#N)cc3)[C@@H](CO)O[C@H](OC)[C@@H]2OC1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P03 compound treatment 216240.0 -299000.0 -2.54 181820.0 -340000.0 -2.88 -3.8348 -0.998 2142593 PK04_098301 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccccc4OCCO)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P04 compound treatment 379910.0 -135000.0 -1.15 219360.0 -302000.0 -2.56 -2.6251 -0.9345 3000699 PK04_098302 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)CCc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P05 compound treatment 307860.0 -207000.0 -1.76 263640.0 -258000.0 -2.19 -2.7929 -0.9943 2144921 PK04_098303 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8ccccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P06 compound treatment 254370.0 -261000.0 -2.22 212080.0 -309000.0 -2.62 -3.424 -0.9965 3000700 PK04_098304 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P07 compound treatment 355200.0 -160000.0 -1.36 230340.0 -291000.0 -2.47 -2.7079 -0.9605 2143937 PK04_098305 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccccc4OCCO)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P08 compound treatment 314670.0 -200000.0 -1.7 257380.0 -264000.0 -2.24 -2.7895 -0.9909 3000701 PK04_098306 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)c2c(OC)cccc2OC)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P09 compound treatment 335140.0 -180000.0 -1.53 242770.0 -279000.0 -2.36 -2.754 -0.9778 2144785 PK04_098307 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9ccccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P10 compound treatment 371760.0 -143000.0 -1.22 299000.0 -223000.0 -1.89 -2.1964 -0.9776 3089322 PK04_098308 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccccc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P11 mock treatment 209120.0 -306000.0 -2.6 285070.0 -236000.0 -2.01 -3.2584 -0.9917 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P12 mock treatment 354680.0 -160000.0 -1.36 377080.0 -144000.0 -1.23 -1.8308 -0.9986 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P13 compound treatment 255650.0 -259000.0 -2.21 330610.0 -191000.0 -1.62 -2.7053 -0.9884 2144213 PK04_098309 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCN(CC7)c8ncccn8)c9cc(C#Cc%10ccc(OC)cc%10)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P14 compound treatment 299840.0 -215000.0 -1.83 234360.0 -287000.0 -2.44 -3.0168 -0.9901 3089323 PK04_098310 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2cccc(F)c2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P15 compound treatment 331580.0 -183000.0 -1.56 243900.0 -278000.0 -2.35 -2.7686 -0.98 2144225 PK04_098311 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(O)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)NCC=C)c7cc(C#CCNC(=O)N)ccc17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P16 compound treatment 303040.0 -212000.0 -1.8 272530.0 -249000.0 -2.11 -2.7686 -0.9969 3000703 PK04_098312 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(OC)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P17 compound treatment 224710.0 -290000.0 -2.47 186300.0 -335000.0 -2.84 -3.757 -0.9975 2141953 PK04_098313 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(OCCO)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P18 compound treatment 256610.0 -258000.0 -2.2 210830.0 -311000.0 -2.64 -3.418 -0.9959 3000704 PK04_098314 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc3OCOc3c2)[C@H](OC(=O)c4cc5ccccc5[nH]4)[C@H]1OC(=O)c6cc7ccccc7[nH]6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P19 compound treatment 264800.0 -250000.0 -2.13 311440.0 -210000.0 -1.78 -2.7652 -0.9961 2143337 PK04_098315 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCc8cc(OC)c(OC)cc8C7)c9cc(C#CCCO)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P20 compound treatment 253510.0 -262000.0 -2.22 248680.0 -273000.0 -2.31 -3.2096 -0.9998 3089326 PK04_098316 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(Br)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P21 compound treatment 202130.0 -313000.0 -2.66 243040.0 -278000.0 -2.36 -3.5525 -0.9982 2143233 PK04_098317 COCCOC(=O)N1C(=O)[C@]2([C@@H]([C@@H]3N([C@@H]2c4ccc(OCCO)cc4)[C@H]([C@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)N7CCCCCCC7)c8cc(C#Cc9ccc(OC)cc9)ccc18 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P22 compound treatment 304480.0 -211000.0 -1.79 312450.0 -209000.0 -1.77 -2.5205 -1.0 3089328 PK04_098318 CO[C@H]1O[C@H](CO)[C@@H](OC(=O)Nc2ccc(C#N)cc2)[C@H](OC(=O)c3cc4ccccc4[nH]3)[C@H]1OC(=O)c5cc6ccccc6[nH]5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P23 compound treatment 194240.0 -321000.0 -2.73 296560.0 -225000.0 -1.91 -3.279 -0.9847 2142969 PK04_098319 COCCOC(=O)N1C(=O)[C@@]2([C@H]([C@H]3N([C@H]2c4ccc(O)cc4)[C@@H]([C@@H](OC3=O)c5ccccc5)c6ccccc6)C(=O)Nc7nc8ccccc8s7)c9cc(C#CCNC(=O)N)ccc19 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2098 P24 compound treatment 250240.0 -265000.0 -2.25 215040.0 -306000.0 -2.6 -3.4311 -0.9975 3189006 PK04_098320 CC(C)[Si](OCCCNS(=O)(=O)c1ccc(Br)cc1)(C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A01 compound treatment 281220.0 -255000.0 -2.17 487480.0 -54100.0 -0.46 -1.8588 -0.8381 3052787 PK04_100001 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A02 compound treatment 530960.0 -5330.0 -0.05 318180.0 -223000.0 -1.9 -1.372 -0.7238 3052649 PK04_100002 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A03 compound treatment 510650.0 -25600.0 -0.22 527130.0 -14400.0 -0.12 -0.2409 -0.9628 3176622 PK04_100003 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A04 compound treatment 283610.0 -253000.0 -2.15 525730.0 -15800.0 -0.13 -1.615 -0.7499 3175961 PK04_100004 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A05 compound treatment 541640.0 5350.0 0.05 529040.0 -12500.0 -0.11 -0.043 -0.3716 3176556 PK04_100005 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A06 compound treatment 571200.0 34900.0 0.3 419290.0 -122000.0 -1.04 -0.5235 -0.4851 3176630 PK04_100006 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A07 compound treatment 571650.0 35400.0 0.3 542720.0 1140.0 0.01 0.2196 0.7295 3175901 PK04_100007 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A08 compound treatment 417220.0 -119000.0 -1.01 487520.0 -54100.0 -0.46 -1.0405 -0.9358 3176729 PK04_100008 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A09 compound treatment 318180.0 -218000.0 -1.86 399860.0 -142000.0 -1.2 -2.1621 -0.9779 3052580 PK04_100009 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A10 compound treatment 379210.0 -157000.0 -1.34 497090.0 -44500.0 -0.38 -1.2117 -0.8727 3176731 PK04_100010 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A11 compound treatment 373830.0 -162000.0 -1.38 288110.0 -253000.0 -2.15 -2.4976 -0.9772 3176633 PK04_100011 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A12 compound treatment 554760.0 18500.0 0.16 467460.0 -74100.0 -0.63 -0.3334 -0.5145 3176445 PK04_100012 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A13 mock treatment 592080.0 55800.0 0.47 513020.0 -28600.0 -0.24 0.1643 0.3084 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A14 mock treatment 521480.0 -14800.0 -0.13 477140.0 -64400.0 -0.55 -0.4756 -0.8478 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A15 compound treatment 448700.0 -87600.0 -0.75 413930.0 -128000.0 -1.08 -1.2925 -0.9834 3175963 PK04_100013 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A16 compound treatment 489440.0 -46800.0 -0.4 512380.0 -29200.0 -0.25 -0.4569 -0.9738 3052785 PK04_100014 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A17 compound treatment 511170.0 -25100.0 -0.21 523100.0 -18500.0 -0.16 -0.2619 -0.9884 3052837 PK04_100015 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A18 compound treatment 556520.0 20200.0 0.17 520120.0 -21500.0 -0.18 -0.007 -0.0279 3176262 PK04_100016 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A19 compound treatment 530240.0 -6050.0 -0.05 465020.0 -76600.0 -0.65 -0.4956 -0.7607 3176686 PK04_100017 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A20 compound treatment 498480.0 -37800.0 -0.32 316060.0 -226000.0 -1.91 -1.5801 -0.8146 3176371 PK04_100018 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A21 compound treatment 369850.0 -166000.0 -1.42 512680.0 -28900.0 -0.25 -1.1745 -0.8174 3052829 PK04_100019 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A22 compound treatment 455370.0 -80900.0 -0.69 560410.0 18800.0 0.16 -0.3738 -0.5289 3052833 PK04_100020 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A23 compound treatment 500540.0 -35700.0 -0.3 537640.0 -3940.0 -0.03 -0.2386 -0.7801 3052878 PK04_100021 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 A24 compound treatment 478400.0 -57900.0 -0.49 445760.0 -95800.0 -0.81 -0.9229 -0.9712 3052694 PK04_100022 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B01 compound treatment 514040.0 -22200.0 -0.19 575640.0 34100.0 0.29 0.0705 0.2041 3052928 PK04_100023 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B02 compound treatment 551530.0 15200.0 0.13 570970.0 29400.0 0.25 0.268 0.9536 3052800 PK04_100024 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B03 compound treatment 521370.0 -14900.0 -0.13 565780.0 24200.0 0.21 0.0554 0.2297 3052842 PK04_100025 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B04 compound treatment 347310.0 -189000.0 -1.61 586020.0 44400.0 0.38 -0.8702 -0.527 3176782 PK04_100026 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B05 compound treatment 561680.0 25400.0 0.22 545210.0 3630.0 0.03 0.1746 0.7999 3175971 PK04_100027 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B06 compound treatment 543050.0 6760.0 0.06 536540.0 -5040.0 -0.04 0.0105 0.1462 3176561 PK04_100028 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B07 compound treatment 578760.0 42500.0 0.36 488340.0 -53200.0 -0.45 -0.0638 -0.1103 3176369 PK04_100029 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B08 compound treatment 480200.0 -56100.0 -0.48 521310.0 -20300.0 -0.17 -0.459 -0.9049 3176441 PK04_100030 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B09 compound treatment 541570.0 5280.0 0.04 385650.0 -156000.0 -1.32 -0.9035 -0.6827 3052641 PK04_100031 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B10 compound treatment 522120.0 -14200.0 -0.12 575650.0 34100.0 0.29 0.1192 0.3805 3176555 PK04_100032 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B11 compound treatment 396930.0 -139000.0 -1.19 543230.0 1650.0 0.01 -0.8284 -0.6987 3176554 PK04_100033 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B12 compound treatment 490950.0 -45300.0 -0.39 511110.0 -30500.0 -0.26 -0.4555 -0.981 3052747 PK04_100034 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B13 mock treatment 558480.0 22200.0 0.19 531220.0 -10400.0 -0.09 0.0714 0.3428 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B14 mock treatment 610580.0 74300.0 0.63 609440.0 67900.0 0.58 0.854 0.9989 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B15 compound treatment 486200.0 -50100.0 -0.43 424480.0 -117000.0 -0.99 -1.0037 -0.9286 3052707 PK04_100035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B16 compound treatment 558370.0 22100.0 0.19 511090.0 -30500.0 -0.26 -0.05 -0.1565 3176447 PK04_100036 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B17 compound treatment 480600.0 -55700.0 -0.47 532390.0 -9190.0 -0.08 -0.3901 -0.8125 3176194 PK04_100037 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B18 compound treatment 572190.0 35900.0 0.31 405060.0 -137000.0 -1.16 -0.6029 -0.5034 3176504 PK04_100038 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B19 compound treatment 512100.0 -24200.0 -0.21 433070.0 -109000.0 -0.92 -0.7963 -0.8443 3176439 PK04_100039 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B20 compound treatment 513980.0 -22300.0 -0.19 546400.0 4820.0 0.04 -0.1053 -0.5422 3176678 PK04_100040 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B21 compound treatment 602590.0 66300.0 0.56 566400.0 24800.0 0.21 0.5478 0.9098 3176260 PK04_100041 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B22 compound treatment 467490.0 -68800.0 -0.59 492960.0 -48600.0 -0.41 -0.7055 -0.9853 3176621 PK04_100042 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B23 compound treatment 534530.0 -1760.0 -0.01 575910.0 34300.0 0.29 0.1954 0.6699 3176370 PK04_100043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 B24 compound treatment 419150.0 -117000.0 -1.0 457720.0 -83900.0 -0.71 -1.2076 -0.9863 3176636 PK04_100044 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C01 compound treatment 512100.0 -24200.0 -0.21 479910.0 -61700.0 -0.52 -0.5154 -0.9169 3052532 PK04_100045 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C02 compound treatment 510560.0 -25700.0 -0.22 524120.0 -17500.0 -0.15 -0.2595 -0.9819 3052638 PK04_100046 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C03 compound treatment 489280.0 -47000.0 -0.4 521990.0 -19600.0 -0.17 -0.4003 -0.9243 3052540 PK04_100047 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C04 compound treatment 501040.0 -35200.0 -0.3 386160.0 -155000.0 -1.32 -1.1442 -0.8463 3052751 PK04_100048 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C05 compound treatment 547970.0 11700.0 0.1 496930.0 -44600.0 -0.38 -0.1975 -0.5044 3052702 PK04_100049 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C06 compound treatment 549440.0 13200.0 0.11 544480.0 2900.0 0.02 0.0965 0.8426 3176680 PK04_100050 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C07 compound treatment 557940.0 21700.0 0.18 486430.0 -55100.0 -0.47 -0.2005 -0.3988 3052743 PK04_100051 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C08 compound treatment 520220.0 -16100.0 -0.14 446900.0 -94700.0 -0.8 -0.6645 -0.8157 3176043 PK04_100052 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C09 compound treatment 541830.0 5540.0 0.05 501250.0 -40300.0 -0.34 -0.2085 -0.6039 3052925 PK04_100053 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C10 compound treatment 472500.0 -63800.0 -0.54 520520.0 -21100.0 -0.18 -0.51 -0.8927 3176324 PK04_100054 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C11 mock treatment 534730.0 -1560.0 -0.01 474050.0 -67500.0 -0.57 -0.4144 -0.7233 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C12 mock treatment 475320.0 -61000.0 -0.52 545560.0 3980.0 0.03 -0.3429 -0.6596 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C13 compound treatment 435400.0 -101000.0 -0.86 488050.0 -53500.0 -0.45 -0.9279 -0.9557 3176376 PK04_100055 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C14 compound treatment 452580.0 -83700.0 -0.71 443390.0 -98200.0 -0.83 -1.0925 -0.997 3176324 PK04_100056 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C15 mock treatment 404600.0 -132000.0 -1.12 497520.0 -44100.0 -0.37 -1.0564 -0.8945 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C16 mock treatment 508800.0 -27500.0 -0.23 472680.0 -68900.0 -0.58 -0.5786 -0.9192 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C17 compound treatment 491420.0 -44900.0 -0.38 407360.0 -134000.0 -1.14 -1.0749 -0.8952 3052884 PK04_100057 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C18 compound treatment 540910.0 4620.0 0.04 505920.0 -35700.0 -0.3 -0.1861 -0.61 3176562 PK04_100058 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C19 compound treatment 531050.0 -5240.0 -0.04 457410.0 -84200.0 -0.71 -0.5363 -0.7498 3176124 PK04_100059 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C20 compound treatment 539400.0 3110.0 0.03 482820.0 -58800.0 -0.5 -0.3337 -0.6686 3052784 PK04_100060 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C21 compound treatment 508100.0 -28200.0 -0.24 374450.0 -167000.0 -1.42 -1.172 -0.8151 3052792 PK04_100061 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C22 compound treatment 509820.0 -26500.0 -0.23 535090.0 -6490.0 -0.06 -0.1981 -0.8547 3052749 PK04_100062 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C23 compound treatment 451200.0 -85100.0 -0.72 490130.0 -51400.0 -0.44 -0.8204 -0.9707 3176204 PK04_100063 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 C24 compound treatment 467810.0 -68500.0 -0.58 520000.0 -21600.0 -0.18 -0.5413 -0.8865 3176041 PK04_100064 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D01 compound treatment 519530.0 -16800.0 -0.14 472690.0 -68900.0 -0.58 -0.514 -0.8545 3052926 PK04_100065 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D02 compound treatment 454560.0 -81700.0 -0.7 543040.0 1460.0 0.01 -0.4828 -0.6944 3176201 PK04_100066 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D03 compound treatment 495950.0 -40300.0 -0.34 552210.0 10600.0 0.09 -0.1789 -0.5041 3052885 PK04_100067 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D04 compound treatment 547840.0 11600.0 0.1 542850.0 1270.0 0.01 0.0771 0.7802 3176377 PK04_100068 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D05 compound treatment 483470.0 -52800.0 -0.45 531590.0 -9990.0 -0.08 -0.3776 -0.8259 3052790 PK04_100069 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D06 compound treatment 499330.0 -37000.0 -0.31 565280.0 23700.0 0.2 -0.0801 -0.2147 3052881 PK04_100070 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D07 compound treatment 431770.0 -105000.0 -0.89 521920.0 -19700.0 -0.17 -0.7466 -0.8253 3052536 PK04_100071 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D08 compound treatment 530800.0 -5490.0 -0.05 527770.0 -13800.0 -0.12 -0.1158 -0.9187 3052923 PK04_100072 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D09 compound treatment 408270.0 -128000.0 -1.09 515550.0 -26000.0 -0.22 -0.9262 -0.8335 3052690 PK04_100073 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D10 compound treatment 541500.0 5210.0 0.04 563610.0 22000.0 0.19 0.1635 0.8513 3052841 PK04_100074 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D11 mock treatment 536480.0 194.0 0.0 539910.0 -1670.0 -0.01 -0.0088 -0.6205 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D12 mock treatment 556020.0 19700.0 0.17 540020.0 -1560.0 -0.01 0.1094 0.6495 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D13 compound treatment 469060.0 -67200.0 -0.57 462740.0 -78800.0 -0.67 -0.8773 -0.997 3176624 PK04_100075 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D14 compound treatment 554560.0 18300.0 0.16 506370.0 -35200.0 -0.3 -0.1012 -0.3007 3176375 PK04_100076 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D15 mock treatment 561940.0 25700.0 0.22 544100.0 2520.0 0.02 0.1695 0.7728 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D16 mock treatment 544870.0 8580.0 0.07 532760.0 -8820.0 -0.07 -0.0012 -0.0119 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D17 compound treatment 515200.0 -21100.0 -0.18 512490.0 -29100.0 -0.25 -0.3013 -0.9877 3176503 PK04_100077 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D18 compound treatment 525400.0 -10900.0 -0.09 544980.0 3400.0 0.03 -0.0451 -0.4646 3052543 PK04_100078 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D19 compound treatment 573570.0 37300.0 0.32 529570.0 -12000.0 -0.1 0.1523 0.4571 3052538 PK04_100079 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D20 compound treatment 566730.0 30400.0 0.26 554670.0 13100.0 0.11 0.2617 0.9286 3052705 PK04_100080 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D21 compound treatment 505550.0 -30700.0 -0.26 482110.0 -59500.0 -0.5 -0.5416 -0.9532 3052691 PK04_100081 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D22 compound treatment 494840.0 -41400.0 -0.35 498510.0 -43100.0 -0.37 -0.5076 -0.9998 3052534 PK04_100082 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D23 compound treatment 460480.0 -75800.0 -0.64 431050.0 -111000.0 -0.94 -1.119 -0.9833 3176202 PK04_100083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 D24 compound treatment 513040.0 -23200.0 -0.2 537840.0 -3740.0 -0.03 -0.1622 -0.8101 3176197 PK04_100084 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E01 mock treatment 571640.0 35400.0 0.3 545160.0 3580.0 0.03 0.2342 0.7746 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E02 mock treatment 581390.0 45100.0 0.38 581610.0 40000.0 0.34 0.5115 0.9981 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E03 compound treatment 545640.0 9350.0 0.08 529650.0 -11900.0 -0.1 -0.0153 -0.1186 3176672 PK04_100085 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E04 compound treatment 537640.0 1350.0 0.01 510970.0 -30600.0 -0.26 -0.1754 -0.6751 3052883 PK04_100086 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E05 compound treatment 559160.0 22900.0 0.19 439940.0 -102000.0 -0.86 -0.472 -0.5341 3176126 PK04_100087 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E06 compound treatment 550110.0 13800.0 0.12 477800.0 -63800.0 -0.54 -0.2994 -0.5408 3052533 PK04_100088 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E07 compound treatment 511420.0 -24900.0 -0.21 327440.0 -214000.0 -1.82 -1.434 -0.7842 3175839 PK04_100089 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E08 compound treatment 515930.0 -20400.0 -0.17 547140.0 5560.0 0.05 -0.0891 -0.4963 3052695 PK04_100090 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E09 mock treatment 598240.0 62000.0 0.53 523570.0 -18000.0 -0.15 0.2647 0.4823 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E10 mock treatment 525150.0 -11100.0 -0.09 552170.0 10600.0 0.09 -0.0034 -0.0264 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E11 compound treatment 417120.0 -119000.0 -1.01 462190.0 -79400.0 -0.67 -1.193 -0.9803 3176568 PK04_100091 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E12 compound treatment 548800.0 12500.0 0.11 526090.0 -15500.0 -0.13 -0.0176 -0.1042 3176044 PK04_100092 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E13 compound treatment 431740.0 -105000.0 -0.89 522030.0 -19500.0 -0.17 -0.7461 -0.8247 3052753 PK04_100093 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E14 compound treatment 510880.0 -25400.0 -0.22 532190.0 -9390.0 -0.08 -0.2091 -0.9079 3175962 PK04_100094 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E15 compound treatment 509090.0 -27200.0 -0.23 517970.0 -23600.0 -0.2 -0.3052 -0.9974 3176325 PK04_100095 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E16 compound treatment 522010.0 -14300.0 -0.12 525230.0 -16300.0 -0.14 -0.1839 -0.9978 3052542 PK04_100096 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E17 mock treatment 544750.0 8460.0 0.07 598650.0 57100.0 0.48 0.3933 0.8034 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E18 mock treatment 519150.0 -17100.0 -0.15 538760.0 -2820.0 -0.02 -0.12 -0.8121 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E19 compound treatment 470420.0 -65900.0 -0.56 418920.0 -123000.0 -1.04 -1.1319 -0.9578 3052746 PK04_100097 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E20 compound treatment 569220.0 32900.0 0.28 549340.0 7760.0 0.07 0.2447 0.8502 3176676 PK04_100098 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E21 compound treatment 405760.0 -131000.0 -1.11 503930.0 -37600.0 -0.32 -1.011 -0.875 3052756 PK04_100099 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E22 compound treatment 561760.0 25500.0 0.22 502590.0 -39000.0 -0.33 -0.0806 -0.2039 3176560 PK04_100100 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E23 compound treatment 517180.0 -19100.0 -0.16 454050.0 -87500.0 -0.74 -0.6399 -0.842 3052487 PK04_100101 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 E24 compound treatment 542140.0 5850.0 0.05 584270.0 42700.0 0.36 0.2913 0.7968 3176563 PK04_100102 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F01 mock treatment 481200.0 -55100.0 -0.47 567200.0 25600.0 0.22 -0.1777 -0.3439 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F02 mock treatment 506500.0 -29800.0 -0.25 559780.0 18200.0 0.15 -0.07 -0.2359 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F03 compound treatment 587970.0 51700.0 0.44 539940.0 -1640.0 -0.01 0.3011 0.6844 3176684 PK04_100103 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F04 compound treatment 501480.0 -34800.0 -0.3 501280.0 -40300.0 -0.34 -0.4511 -0.9974 3176121 PK04_100104 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F05 compound treatment 489170.0 -47100.0 -0.4 547300.0 5720.0 0.05 -0.2491 -0.6169 3176435 PK04_100105 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F06 compound treatment 392760.0 -144000.0 -1.22 516570.0 -25000.0 -0.21 -1.0134 -0.8177 3176627 PK04_100106 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F07 compound treatment 445230.0 -91100.0 -0.77 550090.0 8510.0 0.07 -0.4967 -0.6384 3176774 PK04_100107 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F08 compound treatment 618110.0 81800.0 0.7 583860.0 42300.0 0.36 0.7458 0.9525 3174822 PK04_100108 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F09 mock treatment 577320.0 41000.0 0.35 550620.0 9040.0 0.08 0.3011 0.8424 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F10 mock treatment 614320.0 78000.0 0.66 513560.0 -28000.0 -0.24 0.3014 0.4274 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F11 compound treatment 596040.0 59800.0 0.51 535040.0 -6540.0 -0.06 0.3202 0.6263 3176192 PK04_100109 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F12 compound treatment 492500.0 -43800.0 -0.37 528210.0 -13400.0 -0.11 -0.3436 -0.8824 3052594 PK04_100110 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F13 compound treatment 446360.0 -89900.0 -0.77 539150.0 -2430.0 -0.02 -0.5555 -0.7259 3052748 PK04_100111 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F14 compound treatment 525920.0 -10400.0 -0.09 547680.0 6100.0 0.05 -0.0257 -0.2518 3176567 PK04_100112 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F15 compound treatment 485200.0 -51100.0 -0.43 498600.0 -43000.0 -0.36 -0.5651 -0.9962 3052759 PK04_100113 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F16 compound treatment 486760.0 -49500.0 -0.42 482990.0 -58600.0 -0.5 -0.6493 -0.9966 3176780 PK04_100114 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F17 mock treatment 592000.0 55700.0 0.47 463850.0 -77700.0 -0.66 -0.1311 -0.1614 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F18 mock treatment 603040.0 66800.0 0.57 367040.0 -175000.0 -1.48 -0.6453 -0.407 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F19 compound treatment 442740.0 -93500.0 -0.8 457070.0 -84500.0 -0.72 -1.0696 -0.9986 3176625 PK04_100115 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F20 compound treatment 618660.0 82400.0 0.7 508640.0 -32900.0 -0.28 0.298 0.395 3052750 PK04_100116 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F21 compound treatment 402110.0 -134000.0 -1.14 520050.0 -21500.0 -0.18 -0.9363 -0.8099 3052889 PK04_100117 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F22 compound treatment 489280.0 -47000.0 -0.4 568270.0 26700.0 0.23 -0.1227 -0.2669 3052696 PK04_100118 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F23 compound treatment 482450.0 -53800.0 -0.46 428280.0 -113000.0 -0.96 -1.0034 -0.9425 3176674 PK04_100119 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 F24 compound treatment 494150.0 -42100.0 -0.36 520050.0 -21500.0 -0.18 -0.3826 -0.951 3176436 PK04_100120 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G01 compound treatment 541440.0 5150.0 0.04 375440.0 -166000.0 -1.41 -0.9655 -0.6848 3052845 PK04_100121 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G02 compound treatment 572960.0 36700.0 0.31 475850.0 -65700.0 -0.56 -0.1736 -0.2718 3052835 PK04_100122 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G03 mock treatment 497780.0 -38500.0 -0.33 542630.0 1050.0 0.01 -0.2253 -0.6876 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G04 mock treatment 561090.0 24800.0 0.21 569670.0 28100.0 0.24 0.3177 0.9982 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G05 compound treatment 606500.0 70200.0 0.6 589890.0 48300.0 0.41 0.7122 0.9831 3176502 PK04_100123 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G06 compound treatment 595300.0 59000.0 0.5 553000.0 11400.0 0.1 0.4235 0.8283 3176265 PK04_100124 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G07 compound treatment 541960.0 5670.0 0.05 518880.0 -22700.0 -0.19 -0.102 -0.5139 3052742 PK04_100125 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G08 compound treatment 566090.0 29800.0 0.25 296430.0 -245000.0 -2.08 -1.2911 -0.6163 3052639 PK04_100126 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G09 compound treatment 608160.0 71900.0 0.61 606930.0 65400.0 0.55 0.8244 0.9988 3176200 PK04_100127 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G10 compound treatment 612160.0 75900.0 0.65 589450.0 47900.0 0.41 0.7436 0.9751 3052650 PK04_100128 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G11 compound treatment 537880.0 1590.0 0.01 616840.0 75300.0 0.64 0.461 0.722 3176683 PK04_100129 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G12 compound treatment 560720.0 24400.0 0.21 497990.0 -43600.0 -0.37 -0.1145 -0.2698 3176631 PK04_100130 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G13 compound treatment 531720.0 -4570.0 -0.04 478680.0 -62900.0 -0.53 -0.4047 -0.7566 3176045 PK04_100131 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G14 compound treatment 492440.0 -43800.0 -0.37 510750.0 -30800.0 -0.26 -0.4487 -0.9849 3176196 PK04_100132 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G15 compound treatment 559840.0 23600.0 0.2 360520.0 -181000.0 -1.54 -0.9443 -0.6097 3176446 PK04_100133 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G16 compound treatment 549180.0 12900.0 0.11 524890.0 -16700.0 -0.14 -0.0225 -0.1258 3052834 PK04_100134 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G17 compound treatment 400560.0 -136000.0 -1.15 460130.0 -81400.0 -0.69 -1.305 -0.9698 3052640 PK04_100135 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G18 compound treatment 561790.0 25500.0 0.22 476480.0 -65100.0 -0.55 -0.237 -0.3995 3176727 PK04_100136 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G19 mock treatment 503840.0 -32400.0 -0.28 543160.0 1580.0 0.01 -0.1857 -0.6719 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G20 mock treatment 577450.0 41200.0 0.35 533400.0 -8180.0 -0.07 0.1986 0.5563 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G21 compound treatment 455840.0 -80400.0 -0.68 536320.0 -5260.0 -0.04 -0.5155 -0.7516 3176272 PK04_100137 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G22 compound treatment 531050.0 -5240.0 -0.04 489130.0 -52400.0 -0.44 -0.3461 -0.774 3176261 PK04_100138 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G23 compound treatment 557280.0 21000.0 0.18 510970.0 -30600.0 -0.26 -0.0573 -0.1818 3176513 PK04_100139 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 G24 compound treatment 566650.0 30400.0 0.26 382510.0 -159000.0 -1.35 -0.7715 -0.5615 3052924 PK04_100140 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H01 compound treatment 556040.0 19800.0 0.17 534880.0 -6700.0 -0.06 0.0787 0.4435 3176557 PK04_100141 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H02 compound treatment 418080.0 -118000.0 -1.01 615780.0 74200.0 0.63 -0.266 -0.2242 3052875 PK04_100142 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H03 mock treatment 342960.0 -193000.0 -1.64 553630.0 12100.0 0.1 -1.0907 -0.6619 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H04 mock treatment 479110.0 -57200.0 -0.49 392000.0 -150000.0 -1.27 -1.2411 -0.9134 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H05 compound treatment 446720.0 -89600.0 -0.76 263240.0 -278000.0 -2.36 -2.2083 -0.8901 3052652 PK04_100143 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H06 compound treatment 585730.0 49400.0 0.42 581540.0 40000.0 0.34 0.5371 0.9943 3052786 PK04_100144 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H07 compound treatment 408920.0 -127000.0 -1.08 477720.0 -63900.0 -0.54 -1.1492 -0.9487 3176328 PK04_100145 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H08 compound treatment 575800.0 39500.0 0.34 594110.0 52500.0 0.45 0.5528 0.9903 3176321 PK04_100146 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H09 compound treatment 524680.0 -11600.0 -0.1 437970.0 -104000.0 -0.88 -0.6913 -0.7816 3176735 PK04_100147 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H10 compound treatment 360020.0 -176000.0 -1.5 554360.0 12800.0 0.11 -0.9837 -0.6543 3175969 PK04_100148 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H11 compound treatment 552440.0 16200.0 0.14 208800.0 -333000.0 -2.82 -1.8989 -0.6719 3176193 PK04_100149 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H12 compound treatment 432390.0 -104000.0 -0.88 434470.0 -107000.0 -0.91 -1.2674 -0.9999 3176050 PK04_100150 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H13 compound treatment 501450.0 -34800.0 -0.3 367320.0 -174000.0 -1.48 -1.2548 -0.8323 3176569 PK04_100151 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H14 compound treatment 555540.0 19300.0 0.16 474750.0 -66800.0 -0.57 -0.285 -0.483 3052874 PK04_100152 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H15 compound treatment 474560.0 -61700.0 -0.53 349120.0 -192000.0 -1.63 -1.5257 -0.8897 3052832 PK04_100153 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H16 compound treatment 523370.0 -12900.0 -0.11 485490.0 -56100.0 -0.48 -0.4141 -0.8481 3176267 PK04_100154 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H17 compound treatment 569830.0 33500.0 0.29 456080.0 -85500.0 -0.73 -0.311 -0.3991 3176378 PK04_100155 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H18 compound treatment 537010.0 724.0 0.01 393650.0 -148000.0 -1.25 -0.8829 -0.7036 3176322 PK04_100156 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H19 mock treatment 541410.0 5120.0 0.04 524060.0 -17500.0 -0.15 -0.0742 -0.4795 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H20 mock treatment 627390.0 91100.0 0.78 559960.0 18400.0 0.16 0.6583 0.8327 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H21 compound treatment 560880.0 24600.0 0.21 537980.0 -3600.0 -0.03 0.1264 0.5977 3052801 PK04_100157 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H22 compound treatment 538920.0 2630.0 0.02 558510.0 16900.0 0.14 0.1174 0.8076 3176726 PK04_100158 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H23 compound treatment 467300.0 -69000.0 -0.59 474400.0 -67200.0 -0.57 -0.8179 -0.9999 3176558 PK04_100159 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 H24 compound treatment 473530.0 -62800.0 -0.53 536640.0 -4940.0 -0.04 -0.4071 -0.7602 3052704 PK04_100160 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I01 compound treatment 621560.0 85300.0 0.73 525120.0 -16500.0 -0.14 0.4143 0.5608 3052648 PK04_100161 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I02 compound treatment 578600.0 42300.0 0.36 597280.0 55700.0 0.47 0.5887 0.991 3176506 PK04_100162 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I03 compound treatment 519380.0 -16900.0 -0.14 443080.0 -98500.0 -0.84 -0.6925 -0.8168 3176274 PK04_100163 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I04 compound treatment 593380.0 57100.0 0.49 595630.0 54100.0 0.46 0.6677 0.9996 3176679 PK04_100164 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I05 mock treatment 596090.0 59800.0 0.51 609600.0 68000.0 0.58 0.7678 0.998 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I06 mock treatment 489460.0 -46800.0 -0.4 596530.0 55000.0 0.47 0.0479 0.0782 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I07 compound treatment 523360.0 -12900.0 -0.11 517810.0 -23800.0 -0.2 -0.2203 -0.9594 3052930 PK04_100165 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I08 compound treatment 581760.0 45500.0 0.39 561550.0 20000.0 0.17 0.3934 0.9314 3176444 PK04_100166 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I09 compound treatment 587440.0 51200.0 0.44 623490.0 81900.0 0.69 0.7991 0.9746 3052697 PK04_100167 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I10 compound treatment 616680.0 80400.0 0.68 597340.0 55800.0 0.47 0.8181 0.9838 3176731 PK04_100168 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I11 compound treatment 502980.0 -33300.0 -0.28 557680.0 16100.0 0.14 -0.1038 -0.3299 3052535 PK04_100169 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I12 compound treatment 418560.0 -118000.0 -1.0 532290.0 -9290.0 -0.08 -0.7639 -0.7604 3176198 PK04_100170 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I13 compound treatment 539330.0 3040.0 0.03 501840.0 -39700.0 -0.34 -0.22 -0.6509 3176119 PK04_100171 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I14 compound treatment 585250.0 49000.0 0.42 605080.0 63500.0 0.54 0.6755 0.9919 3176442 PK04_100172 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I15 compound treatment 563760.0 27500.0 0.23 540120.0 -1460.0 -0.01 0.1565 0.6688 3176566 PK04_100173 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I16 compound treatment 584260.0 48000.0 0.41 572320.0 30700.0 0.26 0.473 0.9766 3052844 PK04_100174 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I17 compound treatment 511780.0 -24500.0 -0.21 584440.0 42900.0 0.36 0.1097 0.2617 3176781 PK04_100175 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I18 compound treatment 641380.0 105000.0 0.89 599390.0 57800.0 0.49 0.979 0.96 3052891 PK04_100176 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I19 compound treatment 516800.0 -19500.0 -0.17 589070.0 47500.0 0.4 0.1677 0.3848 3052840 PK04_100177 OC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I20 compound treatment 600710.0 64400.0 0.55 562300.0 20700.0 0.18 0.5119 0.8893 3174821 PK04_100178 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I21 mock treatment 619870.0 83600.0 0.71 570670.0 29100.0 0.25 0.6773 0.8999 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I22 mock treatment 450720.0 -85600.0 -0.73 472830.0 -68700.0 -0.58 -0.9271 -0.994 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I23 compound treatment 527750.0 -8540.0 -0.07 549390.0 7810.0 0.07 -0.0045 -0.0456 3176670 PK04_100179 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 I24 compound treatment 511930.0 -24400.0 -0.21 552960.0 11400.0 0.1 -0.0782 -0.3422 3176728 PK04_100180 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J01 compound treatment 380480.0 -156000.0 -1.33 526400.0 -15200.0 -0.13 -1.0283 -0.7721 3176783 PK04_100181 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J02 compound treatment 469760.0 -66500.0 -0.57 483790.0 -57800.0 -0.49 -0.7468 -0.9974 3176448 PK04_100182 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J03 compound treatment 498160.0 -38100.0 -0.32 570080.0 28500.0 0.24 -0.0584 -0.1443 3176047 PK04_100183 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J04 compound treatment 361570.0 -175000.0 -1.49 398260.0 -143000.0 -1.22 -1.9107 -0.995 3176269 PK04_100184 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J05 mock treatment 470970.0 -65300.0 -0.56 640060.0 98500.0 0.84 0.1978 0.1972 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J06 mock treatment 613560.0 77300.0 0.66 617890.0 76300.0 0.65 0.9226 1.0 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J07 compound treatment 586430.0 50100.0 0.43 595810.0 54200.0 0.46 0.6269 0.9993 3176635 PK04_100185 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J08 compound treatment 594620.0 58300.0 0.5 567540.0 26000.0 0.22 0.5066 0.9332 3176114 PK04_100186 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J09 compound treatment 605130.0 68800.0 0.59 595860.0 54300.0 0.46 0.7397 0.9929 3175966 PK04_100187 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J10 compound treatment 576040.0 39800.0 0.34 612230.0 70700.0 0.6 0.6629 0.9633 3052757 PK04_100188 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J11 compound treatment 563210.0 26900.0 0.23 617690.0 76100.0 0.65 0.6185 0.9028 3174819 PK04_100189 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J12 compound treatment 598680.0 62400.0 0.53 571150.0 29600.0 0.25 0.5527 0.9415 3176738 PK04_100190 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J13 compound treatment 590510.0 54200.0 0.46 623270.0 81700.0 0.69 0.8162 0.9804 3176380 PK04_100191 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J14 compound treatment 459840.0 -76400.0 -0.65 606510.0 64900.0 0.55 -0.0704 -0.0826 3176199 PK04_100192 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J15 compound treatment 594840.0 58600.0 0.5 585140.0 43600.0 0.37 0.6135 0.9892 3176623 PK04_100193 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J16 compound treatment 507840.0 -28400.0 -0.24 531890.0 -9690.0 -0.08 -0.2292 -0.8969 3176632 PK04_100194 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J17 compound treatment 632640.0 96400.0 0.82 390370.0 -151000.0 -1.28 -0.3273 -0.215 3052795 PK04_100195 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J18 compound treatment 560060.0 23800.0 0.2 604220.0 62600.0 0.53 0.5188 0.9124 3052636 PK04_100196 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J19 compound treatment 462320.0 -74000.0 -0.63 466910.0 -74700.0 -0.63 -0.8928 -1.0 3052591 PK04_100197 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J20 compound treatment 563840.0 27600.0 0.23 614490.0 72900.0 0.62 0.6031 0.9118 3176629 PK04_100198 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J21 mock treatment 500480.0 -35800.0 -0.3 502840.0 -38700.0 -0.33 -0.4477 -0.9993 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J22 mock treatment 570520.0 34200.0 0.29 563700.0 22100.0 0.19 0.3386 0.9774 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J23 compound treatment 539090.0 2800.0 0.02 543970.0 2390.0 0.02 0.0312 0.9968 3176776 PK04_100199 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 J24 compound treatment 517280.0 -19000.0 -0.16 405650.0 -136000.0 -1.15 -0.9296 -0.7985 3052544 PK04_100200 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K01 compound treatment 549120.0 12800.0 0.11 556670.0 15100.0 0.13 0.1677 0.9969 3176739 PK04_100201 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K02 compound treatment 627230.0 90900.0 0.77 590670.0 49100.0 0.42 0.8416 0.9578 3176042 PK04_100202 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K03 compound treatment 603100.0 66800.0 0.57 573460.0 31900.0 0.27 0.5932 0.9423 3052528 PK04_100203 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K04 compound treatment 581780.0 45500.0 0.39 570880.0 29300.0 0.25 0.4494 0.9771 3176564 PK04_100204 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K05 compound treatment 410010.0 -126000.0 -1.07 647550.0 106000.0 0.9 -0.124 -0.0885 3176329 PK04_100205 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K06 compound treatment 546310.0 10000.0 0.09 396270.0 -145000.0 -1.23 -0.8113 -0.6566 3052588 PK04_100206 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K07 mock treatment 561180.0 24900.0 0.21 369710.0 -172000.0 -1.46 -0.8811 -0.5981 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K08 mock treatment 511470.0 -24800.0 -0.21 621090.0 79500.0 0.67 0.3277 0.4636 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K09 compound treatment 445880.0 -90400.0 -0.77 595540.0 54000.0 0.46 -0.2202 -0.246 3176733 PK04_100207 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K10 compound treatment 597540.0 61300.0 0.52 334510.0 -207000.0 -1.76 -0.8735 -0.4768 3052589 PK04_100208 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K11 compound treatment 556340.0 20100.0 0.17 398140.0 -143000.0 -1.22 -0.7397 -0.6021 3052651 PK04_100209 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K12 compound treatment 368900.0 -167000.0 -1.42 464230.0 -77300.0 -0.66 -1.4709 -0.9381 3176507 PK04_100210 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K13 compound treatment 432560.0 -104000.0 -0.88 573760.0 32200.0 0.27 -0.4309 -0.4665 3052706 PK04_100211 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K14 compound treatment 643040.0 107000.0 0.91 488680.0 -52900.0 -0.45 0.3249 0.3207 3175959 PK04_100212 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K15 mock treatment 537050.0 764.0 0.01 593870.0 52300.0 0.44 0.3183 0.7174 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K16 mock treatment 441240.0 -95000.0 -0.81 635840.0 94300.0 0.8 -0.0063 -0.0056 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K17 compound treatment 605380.0 69100.0 0.59 605300.0 63700.0 0.54 0.7979 0.9991 3174817 PK04_100213 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K18 compound treatment 605200.0 68900.0 0.59 617970.0 76400.0 0.65 0.8728 0.9988 3176725 PK04_100214 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K19 compound treatment 665200.0 129000.0 1.1 592840.0 51300.0 0.43 1.083 0.918 3052537 PK04_100215 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K20 compound treatment 596020.0 59700.0 0.51 596760.0 55200.0 0.47 0.6903 0.9992 3052596 PK04_100216 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K21 compound treatment 441300.0 -95000.0 -0.81 592390.0 50800.0 0.43 -0.2666 -0.2911 3176049 PK04_100217 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K22 compound treatment 585180.0 48900.0 0.42 589670.0 48100.0 0.41 0.5826 1.0 3052637 PK04_100218 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K23 mock treatment 554950.0 18700.0 0.16 563750.0 22200.0 0.19 0.2453 0.9964 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 K24 mock treatment 562980.0 26700.0 0.23 597760.0 56200.0 0.48 0.4976 0.9425 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L01 compound treatment 605730.0 69400.0 0.59 580260.0 38700.0 0.33 0.6498 0.9615 3052595 PK04_100219 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L02 compound treatment 577730.0 41400.0 0.35 599160.0 57600.0 0.49 0.5947 0.9872 3176046 PK04_100220 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L03 compound treatment 564450.0 28200.0 0.24 494470.0 -47100.0 -0.4 -0.1131 -0.2428 3052585 PK04_100221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L04 compound treatment 342490.0 -194000.0 -1.65 548990.0 7410.0 0.06 -1.1213 -0.6796 3176734 PK04_100222 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L05 compound treatment 600560.0 64300.0 0.55 516170.0 -25400.0 -0.22 0.2343 0.3986 3176688 PK04_100223 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L06 compound treatment 371250.0 -165000.0 -1.4 430740.0 -111000.0 -0.94 -1.6576 -0.981 3176372 PK04_100224 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L07 mock treatment 347640.0 -189000.0 -1.6 529290.0 -12300.0 -0.1 -1.2085 -0.7514 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L08 mock treatment 588190.0 51900.0 0.44 590040.0 48500.0 0.41 0.6029 0.9994 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L09 compound treatment 576240.0 40000.0 0.34 626450.0 84900.0 0.72 0.7494 0.9413 3176559 PK04_100225 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L10 compound treatment 492490.0 -43800.0 -0.37 603140.0 61600.0 0.52 0.1058 0.1649 3052527 PK04_100226 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L11 compound treatment 498330.0 -38000.0 -0.32 563390.0 21800.0 0.19 -0.0975 -0.2619 3176432 PK04_100227 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L12 compound treatment 287370.0 -249000.0 -2.12 480390.0 -61200.0 -0.52 -1.8644 -0.8551 3176326 PK04_100228 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L13 compound treatment 284250.0 -252000.0 -2.14 452400.0 -89200.0 -0.76 -2.051 -0.9021 3176737 PK04_100229 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L14 compound treatment 479650.0 -56600.0 -0.48 549020.0 7440.0 0.06 -0.296 -0.6092 3175964 PK04_100230 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L15 mock treatment 472980.0 -63300.0 -0.54 540220.0 -1360.0 -0.01 -0.389 -0.722 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L16 mock treatment 430410.0 -106000.0 -0.9 555790.0 14200.0 0.12 -0.5516 -0.607 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L17 compound treatment 549470.0 13200.0 0.11 574740.0 33200.0 0.28 0.2782 0.9187 3176787 PK04_100231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L18 compound treatment 628400.0 92100.0 0.78 594560.0 53000.0 0.45 0.8719 0.9652 3175960 PK04_100232 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L19 compound treatment 589880.0 53600.0 0.46 581510.0 39900.0 0.34 0.5619 0.9893 3176273 PK04_100233 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L20 compound treatment 547290.0 11000.0 0.09 590660.0 49100.0 0.42 0.3606 0.845 3052882 PK04_100234 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L21 compound treatment 478400.0 -57900.0 -0.49 557870.0 16300.0 0.14 -0.2505 -0.4897 3176053 PK04_100235 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L22 compound treatment 566110.0 29800.0 0.25 507900.0 -33700.0 -0.29 -0.0226 -0.0591 3052696 PK04_100236 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L23 mock treatment 513500.0 -22800.0 -0.19 556230.0 14700.0 0.12 -0.0492 -0.2135 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 L24 mock treatment 482370.0 -53900.0 -0.46 477400.0 -64200.0 -0.54 -0.7093 -0.9964 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M01 compound treatment 567650.0 31400.0 0.27 571840.0 30300.0 0.26 0.3702 0.9998 3176052 PK04_100237 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M02 compound treatment 540160.0 3870.0 0.03 526600.0 -15000.0 -0.13 -0.0665 -0.5069 3176323 PK04_100238 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M03 compound treatment 523090.0 -13200.0 -0.11 572160.0 30600.0 0.26 0.1041 0.3681 3176206 PK04_100239 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M04 compound treatment 535440.0 -846.0 -0.01 569190.0 27600.0 0.23 0.1605 0.685 3052883 PK04_100240 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M05 compound treatment 562840.0 26600.0 0.23 451430.0 -90100.0 -0.76 -0.381 -0.4778 3052744 PK04_100241 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M06 compound treatment 552360.0 16100.0 0.14 527650.0 -13900.0 -0.12 0.0132 0.0728 3176505 PK04_100242 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M07 compound treatment 597370.0 61100.0 0.52 418400.0 -123000.0 -1.04 -0.3714 -0.3182 3176434 PK04_100243 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M08 compound treatment 581600.0 45300.0 0.39 467200.0 -74400.0 -0.63 -0.1735 -0.2347 3176729 PK04_100244 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M09 mock treatment 641120.0 105000.0 0.89 625370.0 83800.0 0.71 1.1332 0.9937 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M10 mock treatment 588400.0 52100.0 0.44 514340.0 -27200.0 -0.23 0.1501 0.3003 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M11 compound treatment 398720.0 -138000.0 -1.17 481600.0 -60000.0 -0.51 -1.1873 -0.9304 3052590 PK04_100245 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M12 compound treatment 575870.0 39600.0 0.34 503140.0 -38400.0 -0.33 0.0076 0.0162 3176565 PK04_100246 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M13 mock treatment 462800.0 -73500.0 -0.63 565120.0 23500.0 0.2 -0.3008 -0.4584 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M14 mock treatment 592360.0 56100.0 0.48 547380.0 5800.0 0.05 0.3721 0.776 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M15 compound treatment 493310.0 -43000.0 -0.37 556560.0 15000.0 0.13 -0.1687 -0.4357 3176508 PK04_100247 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M16 compound treatment 628740.0 92500.0 0.79 589090.0 47500.0 0.4 0.8412 0.9518 3052587 PK04_100248 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M17 compound treatment 580580.0 44300.0 0.38 543850.0 2270.0 0.02 0.2801 0.7423 3052643 PK04_100249 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M18 compound treatment 545400.0 9110.0 0.08 593360.0 51800.0 0.44 0.3654 0.8192 3176777 PK04_100250 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M19 compound treatment 598880.0 62600.0 0.53 564320.0 22700.0 0.19 0.513 0.9057 3052583 PK04_100251 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M20 compound treatment 553340.0 17100.0 0.15 540820.0 -756.0 -0.01 0.0981 0.6752 3052586 PK04_100252 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M21 compound treatment 534970.0 -1320.0 -0.01 557360.0 15800.0 0.13 0.0868 0.6457 3052593 PK04_100253 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M22 compound treatment 554990.0 18700.0 0.16 523080.0 -18500.0 -0.16 0.0016 0.007 3176374 PK04_100254 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M23 compound treatment 529410.0 -6880.0 -0.06 604930.0 63400.0 0.54 0.3386 0.6264 3052699 PK04_100255 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 M24 compound treatment 556160.0 19900.0 0.17 536180.0 -5400.0 -0.05 0.0872 0.4978 3176628 PK04_100256 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N01 compound treatment 553690.0 17400.0 0.15 502340.0 -39200.0 -0.33 -0.1307 -0.3587 3052530 PK04_100257 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N02 compound treatment 525960.0 -10300.0 -0.09 556720.0 15100.0 0.13 0.0287 0.1845 3176510 PK04_100258 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N03 compound treatment 507300.0 -29000.0 -0.25 552060.0 10500.0 0.09 -0.1115 -0.4253 3052646 PK04_100259 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N04 compound treatment 589560.0 53300.0 0.45 587770.0 46200.0 0.39 0.5976 0.9974 3176040 PK04_100260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N05 compound treatment 569610.0 33300.0 0.28 565780.0 24200.0 0.21 0.3456 0.9875 3052838 PK04_100261 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N06 compound treatment 588000.0 51700.0 0.44 594080.0 52500.0 0.45 0.626 1.0 3176263 PK04_100262 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N07 compound treatment 506260.0 -30000.0 -0.26 582350.0 40800.0 0.35 0.0639 0.1487 3176511 PK04_100263 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N08 compound treatment 588820.0 52500.0 0.45 597630.0 56100.0 0.48 0.6522 0.9995 3052644 PK04_100264 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N09 mock treatment 614320.0 78000.0 0.66 582440.0 40900.0 0.35 0.7145 0.9541 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N10 mock treatment 545970.0 9680.0 0.08 586840.0 45300.0 0.38 0.3298 0.8397 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N11 compound treatment 481410.0 -54900.0 -0.47 596560.0 55000.0 0.47 -3.0E-4 -5.0E-4 3052880 PK04_100265 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N12 compound treatment 584740.0 48500.0 0.41 532710.0 -8870.0 -0.08 0.2383 0.5687 3176732 PK04_100266 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N13 mock treatment 614320.0 78000.0 0.66 598940.0 57400.0 0.49 0.8135 0.9883 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N14 mock treatment 587220.0 50900.0 0.43 630170.0 88600.0 0.75 0.8378 0.9658 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N15 compound treatment 605720.0 69400.0 0.59 510840.0 -30700.0 -0.26 0.2333 0.3614 3052703 PK04_100267 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N16 compound treatment 576800.0 40500.0 0.34 413790.0 -128000.0 -1.08 -0.5228 -0.4596 3176120 PK04_100268 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N17 compound treatment 620900.0 84600.0 0.72 599690.0 58100.0 0.49 0.8576 0.983 3052843 PK04_100269 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N18 compound treatment 574240.0 38000.0 0.32 592810.0 51200.0 0.43 0.5356 0.9893 3176116 PK04_100270 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N19 compound treatment 580800.0 44500.0 0.38 549090.0 7510.0 0.06 0.3128 0.8147 3176319 PK04_100271 NCCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N20 compound treatment 591720.0 55400.0 0.47 544370.0 2790.0 0.02 0.3502 0.7417 3052797 PK04_100272 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N21 compound treatment 571740.0 35500.0 0.3 525920.0 -15700.0 -0.13 0.1194 0.3622 3052581 PK04_100273 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N22 compound treatment 507940.0 -28300.0 -0.24 513670.0 -27900.0 -0.24 -0.3379 -1.0 3176118 PK04_100274 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N23 compound treatment 550000.0 13700.0 0.12 557070.0 15500.0 0.13 0.1754 0.9982 3176207 PK04_100275 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 N24 compound treatment 510790.0 -25500.0 -0.22 505600.0 -36000.0 -0.31 -0.3692 -0.986 3176266 PK04_100276 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O01 compound treatment 548400.0 12100.0 0.1 523930.0 -17600.0 -0.15 -0.033 -0.1814 3176687 PK04_100277 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O02 compound treatment 468660.0 -67600.0 -0.58 522140.0 -19400.0 -0.16 -0.5234 -0.8745 3176323 PK04_100278 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O03 compound treatment 554850.0 18600.0 0.16 554480.0 12900.0 0.11 0.1891 0.984 3176438 PK04_100279 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O04 compound treatment 403700.0 -133000.0 -1.13 520750.0 -20800.0 -0.18 -0.9225 -0.808 3176117 PK04_100280 C[N+](C)(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O05 compound treatment 255950.0 -280000.0 -2.38 454370.0 -87200.0 -0.74 -2.2095 -0.8848 3176384 PK04_100281 NCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O06 compound treatment 543420.0 7130.0 0.06 539520.0 -2060.0 -0.02 0.0306 0.4843 3052695 PK04_100282 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O07 compound treatment 443680.0 -92600.0 -0.79 407290.0 -134000.0 -1.14 -1.3626 -0.9838 3052929 PK04_100283 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O08 compound treatment 510950.0 -25300.0 -0.22 564290.0 22700.0 0.19 -0.0162 -0.0559 3052798 PK04_100284 C[N+](C)(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O09 compound treatment 485300.0 -51000.0 -0.43 526210.0 -15400.0 -0.13 -0.3989 -0.8807 3176509 PK04_100285 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O10 compound treatment 514050.0 -22200.0 -0.19 541440.0 -136.0 0.0 -0.1346 -0.7114 3176681 PK04_100286 C[N+](C)(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O11 mock treatment 479450.0 -56800.0 -0.48 555450.0 13900.0 0.12 -0.2587 -0.5198 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O12 mock treatment 494800.0 -41500.0 -0.35 560320.0 18700.0 0.16 -0.1371 -0.3543 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O13 compound treatment 548340.0 12100.0 0.1 533980.0 -7600.0 -0.06 0.0269 0.2225 3176682 PK04_100287 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O14 compound treatment 589720.0 53400.0 0.45 477360.0 -64200.0 -0.54 -0.0637 -0.0898 3176320 PK04_100288 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O15 compound treatment 459630.0 -76700.0 -0.65 439070.0 -103000.0 -0.87 -1.076 -0.9899 3176268 PK04_100289 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O16 compound treatment 518130.0 -18200.0 -0.15 469500.0 -72100.0 -0.61 -0.5415 -0.8588 3176373 PK04_100290 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O17 compound treatment 483560.0 -52700.0 -0.45 471740.0 -69800.0 -0.59 -0.7361 -0.9906 3052700 PK04_100291 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O18 compound treatment 430580.0 -106000.0 -0.9 415680.0 -126000.0 -1.07 -1.391 -0.9963 3176275 PK04_100292 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O19 compound treatment 510880.0 -25400.0 -0.22 473440.0 -68100.0 -0.58 -0.5615 -0.91 3052887 PK04_100293 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O20 compound treatment 438510.0 -97800.0 -0.83 515730.0 -25800.0 -0.22 -0.7432 -0.864 3176039 PK04_100294 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O21 compound treatment 514470.0 -21800.0 -0.19 519400.0 -22200.0 -0.19 -0.2643 -1.0 3176637 PK04_100295 OC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O22 compound treatment 478640.0 -57600.0 -0.49 480800.0 -60800.0 -0.52 -0.7113 -0.9997 3176115 PK04_100296 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O23 compound treatment 430970.0 -105000.0 -0.9 532480.0 -9100.0 -0.08 -0.6881 -0.7652 3052755 PK04_100297 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 O24 compound treatment 439730.0 -96600.0 -0.82 470720.0 -70900.0 -0.6 -1.0058 -0.9882 3176443 PK04_100298 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P01 compound treatment 388490.0 -148000.0 -1.26 418680.0 -123000.0 -1.04 -1.6262 -0.9957 3052698 PK04_100299 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P02 compound treatment 359960.0 -176000.0 -1.5 437510.0 -104000.0 -0.88 -1.6849 -0.968 3176634 PK04_100300 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccc(I)cc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P03 compound treatment 403640.0 -133000.0 -1.13 442930.0 -98600.0 -0.84 -1.3896 -0.9892 3174820 PK04_100301 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P04 compound treatment 283460.0 -253000.0 -2.15 294020.0 -248000.0 -2.1 -3.0058 -0.9999 3052597 PK04_100302 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P05 compound treatment 288600.0 -248000.0 -2.11 277960.0 -264000.0 -2.24 -3.0712 -0.9996 3176270 PK04_100303 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P06 compound treatment 214080.0 -322000.0 -2.74 440960.0 -101000.0 -0.85 -2.5418 -0.8854 3176677 PK04_100304 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P07 compound treatment 372320.0 -164000.0 -1.39 374080.0 -167000.0 -1.42 -1.991 -1.0 3176122 PK04_100305 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@@H]6N7[C@H]([C@H](C(=O)OCC=C)[C@@]68C(=O)Nc9ccccc98)C(=O)O[C@H]([C@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P08 compound treatment 403610.0 -133000.0 -1.13 352220.0 -189000.0 -1.61 -1.9339 -0.9851 3052701 PK04_100306 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P09 compound treatment 403800.0 -132000.0 -1.13 373970.0 -168000.0 -1.42 -1.8023 -0.9934 3175972 PK04_100307 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P10 compound treatment 445630.0 -90700.0 -0.77 443840.0 -97700.0 -0.83 -1.1316 -0.9993 3052830 PK04_100308 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P11 mock treatment 374460.0 -162000.0 -1.38 368880.0 -173000.0 -1.46 -2.0093 -0.9995 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P12 mock treatment 378400.0 -158000.0 -1.34 462600.0 -79000.0 -0.67 -1.4235 -0.9484 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P13 compound treatment 280190.0 -256000.0 -2.18 366280.0 -175000.0 -1.49 -2.592 -0.9827 3052541 PK04_100309 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P14 compound treatment 213760.0 -323000.0 -2.74 308890.0 -233000.0 -1.97 -3.3359 -0.9869 3052545 PK04_100310 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P15 compound treatment 374920.0 -161000.0 -1.37 398600.0 -143000.0 -1.21 -1.8283 -0.9981 3176381 PK04_100311 CN(C)CCCCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P16 compound treatment 315100.0 -221000.0 -1.88 382490.0 -159000.0 -1.35 -2.2848 -0.9867 3052789 PK04_100312 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P17 compound treatment 389970.0 -146000.0 -1.24 392530.0 -149000.0 -1.26 -1.7742 -1.0 3052890 PK04_100313 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P18 compound treatment 291130.0 -245000.0 -2.09 389600.0 -152000.0 -1.29 -2.3863 -0.9733 3176779 PK04_100314 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P19 compound treatment 232380.0 -304000.0 -2.59 253690.0 -288000.0 -2.44 -3.555 -0.9996 3052876 PK04_100315 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P20 compound treatment 353690.0 -183000.0 -1.55 390850.0 -151000.0 -1.28 -2.0025 -0.9953 3176264 PK04_100316 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCCCCCNC(=O)CS 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P21 compound treatment 334880.0 -201000.0 -1.71 327600.0 -214000.0 -1.82 -2.495 -0.9996 3052692 PK04_100317 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCN 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P22 compound treatment 254460.0 -282000.0 -2.4 307630.0 -234000.0 -1.98 -3.0986 -0.9956 3176051 PK04_100318 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P23 compound treatment 336320.0 -200000.0 -1.7 404810.0 -137000.0 -1.16 -2.0233 -0.9826 3052754 PK04_100319 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@@H]5N6[C@H]([C@H](C(=O)OCC=C)[C@@]57C(=O)Nc8ccccc87)C(=O)O[C@H]([C@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2100 P24 compound treatment 258970.0 -277000.0 -2.36 361780.0 -180000.0 -1.53 -2.7467 -0.9777 3176127 PK04_100320 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A01 compound treatment 498630.0 -29600.0 -0.25 330330.0 -149000.0 -1.26 -1.0705 -0.8317 3189007 PK04_101001 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A02 compound treatment 428040.0 -100000.0 -0.85 463630.0 -15500.0 -0.13 -0.6956 -0.8067 3069619 PK04_101002 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A03 compound treatment 485030.0 -43200.0 -0.37 396360.0 -82800.0 -0.7 -0.7562 -0.9543 3189008 PK04_101003 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A04 compound treatment 480860.0 -47300.0 -0.4 411860.0 -67300.0 -0.57 -0.6884 -0.9854 3189009 PK04_101004 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A05 compound treatment 305230.0 -223000.0 -1.9 503430.0 24300.0 0.21 -1.1956 -0.6266 3069620 PK04_101005 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A06 compound treatment 484050.0 -44200.0 -0.38 384370.0 -94800.0 -0.8 -0.8341 -0.94 3189010 PK04_101006 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A07 compound treatment 499130.0 -29100.0 -0.25 423200.0 -55900.0 -0.47 -0.5104 -0.9539 3189011 PK04_101007 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A08 compound treatment 506810.0 -21400.0 -0.18 347310.0 -132000.0 -1.12 -0.9194 -0.8115 3069621 PK04_101008 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A09 compound treatment 504320.0 -23900.0 -0.2 495850.0 16700.0 0.14 -0.0434 -0.1753 3189120 PK04_101009 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A10 compound treatment 489220.0 -39000.0 -0.33 509240.0 30100.0 0.26 -0.054 -0.1289 3069622 PK04_101010 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A11 compound treatment 488230.0 -40000.0 -0.34 426580.0 -52600.0 -0.45 -0.5557 -0.9911 3189121 PK04_101011 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A12 compound treatment 410340.0 -118000.0 -1.0 421390.0 -57700.0 -0.49 -1.0554 -0.9457 3069678 PK04_101012 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A13 mock treatment 461840.0 -66400.0 -0.56 330350.0 -149000.0 -1.26 -1.2917 -0.9342 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A14 mock treatment 469560.0 -58600.0 -0.5 500160.0 21000.0 0.18 -0.2267 -0.4279 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A15 compound treatment 422170.0 -106000.0 -0.9 439100.0 -40000.0 -0.34 -0.878 -0.9109 3189122 PK04_101013 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A16 compound treatment 352000.0 -176000.0 -1.5 494190.0 15100.0 0.13 -0.9697 -0.6445 3069679 PK04_101014 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A17 compound treatment 410350.0 -118000.0 -1.0 471240.0 -7900.0 -0.07 -0.7563 -0.7527 3189123 PK04_101015 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A18 compound treatment 521830.0 -6370.0 -0.05 405720.0 -73400.0 -0.62 -0.4787 -0.7658 3189124 PK04_101016 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A19 compound treatment 514970.0 -13200.0 -0.11 450260.0 -28900.0 -0.24 -0.2528 -0.9378 3069680 PK04_101017 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A20 compound treatment 431840.0 -96400.0 -0.82 436000.0 -43100.0 -0.37 -0.8384 -0.9339 3189125 PK04_101018 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A21 compound treatment 436390.0 -91800.0 -0.78 379870.0 -99300.0 -0.84 -1.1477 -0.9993 3069681 PK04_101019 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A22 compound treatment 469090.0 -59100.0 -0.5 354720.0 -124000.0 -1.06 -1.1019 -0.9425 3189126 PK04_101020 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A23 compound treatment 462570.0 -65600.0 -0.56 407130.0 -72000.0 -0.61 -0.8267 -0.999 3189127 PK04_101021 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 A24 compound treatment 340640.0 -188000.0 -1.6 419580.0 -59600.0 -0.51 -1.4855 -0.8876 3069682 PK04_101022 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B01 compound treatment 560230.0 32000.0 0.27 513460.0 34300.0 0.29 0.3985 0.9995 3189128 PK04_101023 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B02 compound treatment 526530.0 -1670.0 -0.01 502160.0 23000.0 0.2 0.128 0.6538 3189129 PK04_101024 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B03 compound treatment 552380.0 24200.0 0.21 475370.0 -3770.0 -0.03 0.1228 0.5901 3069683 PK04_101025 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B04 compound treatment 518580.0 -9620.0 -0.08 533410.0 54300.0 0.46 0.2676 0.5724 3189130 PK04_101026 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B05 compound treatment 499530.0 -28700.0 -0.24 477310.0 -1830.0 -0.02 -0.1835 -0.7506 3069684 PK04_101027 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B06 compound treatment 543490.0 15300.0 0.13 461360.0 -17800.0 -0.15 -0.0147 -0.0738 3189131 PK04_101028 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B07 compound treatment 465600.0 -62600.0 -0.53 458460.0 -20700.0 -0.18 -0.5006 -0.8928 3189132 PK04_101029 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B08 compound treatment 526740.0 -1460.0 -0.01 500750.0 21600.0 0.18 0.1208 0.6576 3069685 PK04_101030 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B09 compound treatment 558600.0 30400.0 0.26 496900.0 17800.0 0.15 0.2894 0.9669 3189133 PK04_101031 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B10 compound treatment 556390.0 28200.0 0.24 513380.0 34200.0 0.29 0.3749 0.9955 3189129 PK04_101032 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B11 compound treatment 497600.0 -30600.0 -0.26 504090.0 25000.0 0.21 -0.0344 -0.1026 3189134 PK04_101033 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B12 compound treatment 524390.0 -3810.0 -0.03 501600.0 22500.0 0.19 0.1118 0.5784 3069686 PK04_101034 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B13 mock treatment 451060.0 -77100.0 -0.66 535280.0 56100.0 0.48 -0.1273 -0.157 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B14 mock treatment 569770.0 41600.0 0.35 521150.0 42000.0 0.36 0.502 1.0 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B15 compound treatment 534350.0 6150.0 0.05 516480.0 37300.0 0.32 0.261 0.8128 3189135 PK04_101035 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B16 compound treatment 388880.0 -139000.0 -1.19 417360.0 -61800.0 -0.52 -1.2087 -0.9327 3069686 PK04_101036 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B17 compound treatment 459700.0 -68500.0 -0.58 419040.0 -60100.0 -0.51 -0.7726 -0.9978 3189136 PK04_101037 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B18 compound treatment 510890.0 -17300.0 -0.15 509550.0 30400.0 0.26 0.0783 0.2634 3069687 PK04_101038 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B19 compound treatment 355130.0 -173000.0 -1.47 490740.0 11600.0 0.1 -0.9716 -0.6584 3189137 PK04_101039 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B20 compound treatment 528590.0 386.0 0.0 537040.0 57900.0 0.49 0.3496 0.7118 3069688 PK04_101040 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B21 compound treatment 498570.0 -29600.0 -0.25 528690.0 49600.0 0.42 0.119 0.2427 3189138 PK04_101041 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B22 compound treatment 537050.0 8850.0 0.08 525890.0 46800.0 0.4 0.3336 0.8265 3189139 PK04_101042 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B23 compound treatment 526470.0 -1730.0 -0.01 543570.0 64400.0 0.55 0.376 0.6878 3069689 PK04_101043 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 B24 compound treatment 531400.0 3200.0 0.03 555090.0 76000.0 0.64 0.4748 0.7363 3189140 PK04_101044 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C01 compound treatment 419890.0 -108000.0 -0.92 506040.0 26900.0 0.23 -0.4902 -0.5164 3189247 PK04_101045 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C02 compound treatment 484210.0 -44000.0 -0.37 432320.0 -46800.0 -0.4 -0.5455 -0.9996 3069724 PK04_101046 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C03 compound treatment 319490.0 -209000.0 -1.78 454960.0 -24200.0 -0.21 -1.4006 -0.7836 3189248 PK04_101047 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C04 compound treatment 514470.0 -13700.0 -0.12 398310.0 -80800.0 -0.69 -0.5674 -0.8158 3189249 PK04_101048 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C05 compound treatment 514050.0 -14200.0 -0.12 449980.0 -29200.0 -0.25 -0.26 -0.9453 3069725 PK04_101049 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C06 compound treatment 432160.0 -96000.0 -0.82 424480.0 -54700.0 -0.46 -0.9056 -0.964 3189250 PK04_101050 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C07 compound treatment 458430.0 -69800.0 -0.59 392070.0 -87100.0 -0.74 -0.942 -0.9941 3069726 PK04_101051 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C08 compound treatment 399490.0 -129000.0 -1.1 431530.0 -47600.0 -0.4 -1.0599 -0.9081 3189251 PK04_101052 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C09 compound treatment 493130.0 -35100.0 -0.3 444850.0 -34300.0 -0.29 -0.4167 -0.9999 3189252 PK04_101053 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C10 compound treatment 467690.0 -60500.0 -0.51 401250.0 -77900.0 -0.66 -0.8312 -0.9924 3069727 PK04_101054 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C11 mock treatment 439250.0 -89000.0 -0.76 375360.0 -104000.0 -0.88 -1.1576 -0.9972 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C12 mock treatment 492200.0 -36000.0 -0.31 452520.0 -26600.0 -0.23 -0.3762 -0.9888 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C13 compound treatment 449200.0 -79000.0 -0.67 383890.0 -95200.0 -0.81 -1.0466 -0.9958 3189253 PK04_101055 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C14 compound treatment 489680.0 -38500.0 -0.33 418240.0 -60900.0 -0.52 -0.597 -0.9759 3069728 PK04_101056 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C15 mock treatment 482350.0 -45900.0 -0.39 455170.0 -24000.0 -0.2 -0.4196 -0.9539 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C16 mock treatment 517120.0 -11100.0 -0.09 472320.0 -6820.0 -0.06 -0.1076 -0.9725 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C17 compound treatment 500640.0 -27600.0 -0.23 427040.0 -52100.0 -0.44 -0.4783 -0.956 3189254 PK04_101057 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C18 compound treatment 438680.0 -89500.0 -0.76 416980.0 -62200.0 -0.53 -0.9114 -0.9839 3189255 PK04_101058 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C19 compound treatment 458720.0 -69500.0 -0.59 385000.0 -94100.0 -0.8 -0.9826 -0.989 3069729 PK04_101059 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C20 compound treatment 351600.0 -177000.0 -1.5 351680.0 -127000.0 -1.08 -1.8269 -0.987 3189256 PK04_101060 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C21 compound treatment 410350.0 -118000.0 -1.0 439520.0 -39600.0 -0.34 -0.9466 -0.8952 3189257 PK04_101061 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C22 compound treatment 505340.0 -22900.0 -0.19 484480.0 5340.0 0.05 -0.1055 -0.5283 3069730 PK04_101062 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C23 compound treatment 437280.0 -90900.0 -0.77 423010.0 -56100.0 -0.48 -0.8836 -0.9728 3189258 PK04_101063 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 C24 compound treatment 423040.0 -105000.0 -0.89 428770.0 -50400.0 -0.43 -0.9347 -0.9428 3069731 PK04_101064 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D01 compound treatment 491370.0 -36800.0 -0.31 511080.0 31900.0 0.27 -0.03 -0.0724 3189259 PK04_101065 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D02 compound treatment 539940.0 11700.0 0.1 424270.0 -54900.0 -0.47 -0.2585 -0.5431 3069687 PK04_101066 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5ccc(CCO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D03 compound treatment 547890.0 19700.0 0.17 478340.0 -799.0 -0.01 0.1136 0.6779 3189260 PK04_101067 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D04 compound treatment 524130.0 -4070.0 -0.03 441800.0 -37300.0 -0.32 -0.2485 -0.7798 3069688 PK04_101068 OCCc1ccc(cc1)N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D05 compound treatment 492570.0 -35600.0 -0.3 438260.0 -40900.0 -0.35 -0.4596 -0.9978 3069732 PK04_101069 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D06 compound treatment 570420.0 42200.0 0.36 475840.0 -3300.0 -0.03 0.2342 0.65 3189139 PK04_101070 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D07 compound treatment 507260.0 -20900.0 -0.18 511310.0 32200.0 0.27 0.067 0.2055 3189261 PK04_101071 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D08 compound treatment 580500.0 52300.0 0.44 494900.0 15800.0 0.13 0.4091 0.8807 3069733 PK04_101072 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D09 compound treatment 548850.0 20600.0 0.18 492800.0 13700.0 0.12 0.2061 0.9796 3189262 PK04_101073 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D10 compound treatment 503910.0 -24300.0 -0.21 497880.0 18700.0 0.16 -0.0337 -0.1294 3069733 PK04_101074 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4ccc(CCO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D11 mock treatment 585460.0 57300.0 0.49 434900.0 -44200.0 -0.38 0.0791 0.1286 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D12 mock treatment 420270.0 -108000.0 -0.92 432000.0 -47100.0 -0.4 -0.932 -0.9306 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D13 compound treatment 480930.0 -47300.0 -0.4 516680.0 37500.0 0.32 -0.0592 -0.1154 3189263 PK04_101075 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D14 compound treatment 542180.0 14000.0 0.12 494910.0 15800.0 0.13 0.1787 0.9983 3069734 PK04_101076 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D15 mock treatment 607200.0 79000.0 0.67 494320.0 15200.0 0.13 0.5663 0.8275 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D16 mock treatment 588330.0 60100.0 0.51 478720.0 -419.0 0.0 0.3592 0.7022 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D17 compound treatment 510560.0 -17600.0 -0.15 449030.0 -30100.0 -0.26 -0.2867 -0.9679 3189264 PK04_101077 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D18 compound treatment 576420.0 48200.0 0.41 475710.0 -3430.0 -0.03 0.2695 0.6553 3069734 PK04_101078 CC(C)(C)N(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D19 compound treatment 524060.0 -4140.0 -0.04 521220.0 42100.0 0.36 0.2275 0.6342 3069735 PK04_101079 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D20 compound treatment 567610.0 39400.0 0.34 533600.0 54500.0 0.46 0.5637 0.9876 3189265 PK04_101080 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D21 compound treatment 531040.0 2840.0 0.02 536270.0 57100.0 0.48 0.3597 0.7414 3189266 PK04_101081 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D22 compound treatment 543040.0 14800.0 0.13 505920.0 26800.0 0.23 0.2499 0.9615 3189265 PK04_101082 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCOCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D23 compound treatment 483420.0 -44800.0 -0.38 468730.0 -10400.0 -0.09 -0.3318 -0.8485 3069736 PK04_101083 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 D24 compound treatment 498560.0 -29600.0 -0.25 513050.0 33900.0 0.29 0.0251 0.0656 3189267 PK04_101084 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E01 mock treatment 456010.0 -72200.0 -0.61 523560.0 44400.0 0.38 -0.1678 -0.2329 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E02 mock treatment 575570.0 47400.0 0.4 474570.0 -4570.0 -0.04 0.2575 0.6362 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E03 compound treatment 505480.0 -22700.0 -0.19 486240.0 7100.0 0.06 -0.0941 -0.4647 3189373 PK04_101085 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E04 compound treatment 453920.0 -74300.0 -0.63 487240.0 8100.0 0.07 -0.3983 -0.6265 3189374 PK04_101086 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E05 compound treatment 564160.0 36000.0 0.31 278270.0 -201000.0 -1.7 -0.9886 -0.571 3069761 PK04_101087 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E06 compound treatment 535550.0 7350.0 0.06 465170.0 -14000.0 -0.12 -0.0396 -0.2956 3189375 PK04_101088 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E07 compound treatment 533890.0 5690.0 0.05 480130.0 991.0 0.01 0.0401 0.8177 3189376 PK04_101089 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E08 compound treatment 494750.0 -33500.0 -0.28 499740.0 20600.0 0.17 -0.0777 -0.2326 3069762 PK04_101090 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E09 mock treatment 496350.0 -31900.0 -0.27 449480.0 -29700.0 -0.25 -0.3695 -0.9993 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E10 mock treatment 514840.0 -13400.0 -0.11 504700.0 25600.0 0.22 0.0729 0.2979 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E11 compound treatment 477490.0 -50700.0 -0.43 499080.0 19900.0 0.17 -0.1855 -0.4002 3189377 PK04_101091 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E12 compound treatment 531100.0 2900.0 0.02 524640.0 45500.0 0.39 0.2903 0.7507 3069763 PK04_101092 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E13 compound treatment 516160.0 -12000.0 -0.1 476330.0 -2810.0 -0.02 -0.0893 -0.8489 3189378 PK04_101093 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E14 compound treatment 543090.0 14900.0 0.13 481280.0 2140.0 0.02 0.1024 0.8003 3189379 PK04_101094 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E15 compound treatment 400770.0 -127000.0 -1.08 494930.0 15800.0 0.13 -0.6719 -0.6151 3069764 PK04_101095 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E16 compound treatment 456920.0 -71300.0 -0.61 333310.0 -146000.0 -1.24 -1.3035 -0.9462 3189380 PK04_101096 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E17 mock treatment 492270.0 -35900.0 -0.31 552110.0 73000.0 0.62 0.2215 0.3209 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E18 mock treatment 516860.0 -11300.0 -0.1 458140.0 -21000.0 -0.18 -0.1942 -0.9586 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E19 compound treatment 551810.0 23600.0 0.2 540610.0 61500.0 0.52 0.5107 0.914 3069765 PK04_101097 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E20 compound treatment 471580.0 -56600.0 -0.48 521400.0 42300.0 0.36 -0.0871 -0.1451 3189381 PK04_101098 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E21 compound treatment 489990.0 -38200.0 -0.33 489480.0 10300.0 0.09 -0.1679 -0.4985 3189382 PK04_101099 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E22 compound treatment 460580.0 -67600.0 -0.58 465350.0 -13800.0 -0.12 -0.4895 -0.8338 3069730 PK04_101100 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E23 compound treatment 467530.0 -60700.0 -0.52 484490.0 5350.0 0.05 -0.3329 -0.6424 3069766 PK04_101101 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 E24 compound treatment 504600.0 -23600.0 -0.2 486840.0 7700.0 0.07 -0.0958 -0.4537 3069731 PK04_101102 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F01 mock treatment 555450.0 27200.0 0.23 522690.0 43600.0 0.37 0.4251 0.9748 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F02 mock treatment 559360.0 31200.0 0.27 437950.0 -41200.0 -0.35 -0.0596 -0.136 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F03 compound treatment 487070.0 -41100.0 -0.35 481250.0 2110.0 0.02 -0.2348 -0.67 3189383 PK04_101103 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F04 compound treatment 527080.0 -1120.0 -0.01 467790.0 -11300.0 -0.1 -0.0748 -0.7735 3189267 PK04_101104 OCCOCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F05 compound treatment 500800.0 -27400.0 -0.23 468890.0 -10200.0 -0.09 -0.2263 -0.9096 3189384 PK04_101105 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F06 compound treatment 543810.0 15600.0 0.13 305020.0 -174000.0 -1.48 -0.9505 -0.641 3069767 PK04_101106 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F07 compound treatment 524800.0 -3400.0 -0.03 507450.0 28300.0 0.24 0.1493 0.6174 3189385 PK04_101107 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F08 compound treatment 571200.0 43000.0 0.37 501930.0 22800.0 0.19 0.3954 0.9556 3069767 PK04_101108 CCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F09 mock treatment 496800.0 -31400.0 -0.27 529620.0 50500.0 0.43 0.1139 0.2256 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F10 mock treatment 598200.0 70000.0 0.6 413790.0 -65300.0 -0.55 0.0291 0.0358 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F11 compound treatment 363130.0 -165000.0 -1.4 466760.0 -12400.0 -0.11 -1.0673 -0.7579 3069768 PK04_101109 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F12 compound treatment 368250.0 -160000.0 -1.36 294570.0 -185000.0 -1.57 -2.0693 -0.9976 3189386 PK04_101110 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F13 compound treatment 440320.0 -87900.0 -0.75 434880.0 -44300.0 -0.38 -0.7941 -0.9492 3189387 PK04_101111 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F14 compound treatment 467840.0 -60400.0 -0.51 419110.0 -60000.0 -0.51 -0.7232 -1.0 3189386 PK04_101112 CCCCCN(CC=C)C(=O)C1N(CCOCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F15 compound treatment 525040.0 -3160.0 -0.03 425150.0 -54000.0 -0.46 -0.3429 -0.7474 3069769 PK04_101113 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F16 compound treatment 488880.0 -39300.0 -0.33 371490.0 -108000.0 -0.91 -0.8823 -0.9072 3189388 PK04_101114 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F17 mock treatment 537650.0 9450.0 0.08 503790.0 24700.0 0.21 0.2047 0.9137 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F18 mock treatment 479160.0 -49000.0 -0.42 501080.0 21900.0 0.19 -0.1634 -0.3577 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F19 compound treatment 490240.0 -38000.0 -0.32 450910.0 -28200.0 -0.24 -0.3977 -0.9892 3189389 PK04_101115 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F20 compound treatment 532750.0 4550.0 0.04 523250.0 44100.0 0.37 0.2919 0.7761 3189388 PK04_101116 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F21 compound treatment 482770.0 -45400.0 -0.39 387130.0 -92000.0 -0.78 -0.8252 -0.9475 3069770 PK04_101117 OCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F22 compound treatment 516890.0 -11300.0 -0.1 439040.0 -40100.0 -0.34 -0.3086 -0.8729 3189390 PK04_101118 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F23 compound treatment 479420.0 -48800.0 -0.42 401230.0 -77900.0 -0.66 -0.7608 -0.9749 3189391 PK04_101119 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 F24 compound treatment 508800.0 -19400.0 -0.17 506580.0 27400.0 0.23 0.0479 0.1678 3189390 PK04_101120 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)C(C)(C)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G01 compound treatment 415040.0 -113000.0 -0.96 393030.0 -86100.0 -0.73 -1.1972 -0.9907 3189392 PK04_101121 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G02 compound treatment 527870.0 -334.0 0.0 497460.0 18300.0 0.16 0.1079 0.6941 3189374 PK04_101122 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G03 mock treatment 333250.0 -195000.0 -1.66 566530.0 87400.0 0.74 -0.6486 -0.357 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G04 mock treatment 566300.0 38100.0 0.32 476280.0 -2860.0 -0.02 0.212 0.6524 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G05 compound treatment 333070.0 -195000.0 -1.66 429980.0 -49200.0 -0.42 -1.4687 -0.8581 3069794 PK04_101123 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G06 compound treatment 560960.0 32800.0 0.28 491200.0 12100.0 0.1 0.2694 0.9075 3189375 PK04_101124 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G07 compound treatment 503450.0 -24800.0 -0.21 537570.0 58400.0 0.5 0.2016 0.3743 3189393 PK04_101125 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G08 compound treatment 578200.0 50000.0 0.43 520260.0 41100.0 0.35 0.5474 0.9952 3069762 PK04_101126 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G09 compound treatment 525930.0 -2270.0 -0.02 511760.0 32600.0 0.28 0.182 0.6561 3069795 PK04_101127 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G10 compound treatment 498560.0 -29600.0 -0.25 535650.0 56500.0 0.48 0.1606 0.2966 3069763 PK04_101128 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G11 compound treatment 524130.0 -4070.0 -0.03 413760.0 -65400.0 -0.55 -0.4167 -0.7498 3189504 PK04_101129 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G12 compound treatment 416160.0 -112000.0 -0.95 407070.0 -72100.0 -0.61 -1.1063 -0.977 3189379 PK04_101130 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G13 compound treatment 477600.0 -50600.0 -0.43 420840.0 -58300.0 -0.49 -0.6541 -0.9976 3069796 PK04_101131 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G14 compound treatment 477770.0 -50400.0 -0.43 526520.0 47400.0 0.4 -0.0192 -0.0326 3189380 PK04_101132 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G15 compound treatment 473450.0 -54800.0 -0.47 485640.0 6500.0 0.06 -0.2904 -0.6191 3189505 PK04_101133 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G16 compound treatment 395540.0 -133000.0 -1.13 432850.0 -46300.0 -0.39 -1.0757 -0.9002 3189381 PK04_101134 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G17 compound treatment 470240.0 -58000.0 -0.49 484060.0 4920.0 0.04 -0.3192 -0.6449 3189506 PK04_101135 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G18 compound treatment 506900.0 -21300.0 -0.18 549960.0 70800.0 0.6 0.2966 0.4727 3069797 PK04_101136 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G19 mock treatment 591580.0 63400.0 0.54 493390.0 14300.0 0.12 0.4667 0.8447 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G20 mock treatment 581850.0 53600.0 0.46 488890.0 9750.0 0.08 0.3812 0.8219 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G21 compound treatment 527790.0 -414.0 0.0 395060.0 -84100.0 -0.71 -0.5068 -0.7106 3189507 PK04_101137 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G22 compound treatment 501470.0 -26700.0 -0.23 503360.0 24200.0 0.21 -0.0155 -0.0507 3189508 PK04_101138 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G23 compound treatment 505600.0 -22600.0 -0.19 473810.0 -5330.0 -0.05 -0.1679 -0.8502 3069798 PK04_101139 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 G24 compound treatment 482030.0 -46200.0 -0.39 473000.0 -6140.0 -0.05 -0.3146 -0.7939 3189509 PK04_101140 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H01 compound treatment 520320.0 -7880.0 -0.07 438640.0 -40500.0 -0.34 -0.2903 -0.8295 3069799 PK04_101141 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H02 compound treatment 599810.0 71600.0 0.61 375150.0 -104000.0 -0.88 -0.193 -0.18 3189510 PK04_101142 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H03 mock treatment 626500.0 98300.0 0.84 482820.0 3680.0 0.03 0.6134 0.733 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H04 mock treatment 561320.0 33100.0 0.28 535080.0 55900.0 0.47 0.5348 0.969 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H05 compound treatment 545060.0 16900.0 0.14 430340.0 -48800.0 -0.41 -0.1913 -0.4367 3189511 PK04_101143 OCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H06 compound treatment 572090.0 43900.0 0.37 322920.0 -156000.0 -1.33 -0.673 -0.4889 3069800 PK04_101144 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H07 compound treatment 550120.0 21900.0 0.19 376380.0 -103000.0 -0.87 -0.4845 -0.5436 3189512 PK04_101145 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H08 compound treatment 574900.0 46700.0 0.4 552640.0 73500.0 0.62 0.7218 0.9763 3069800 PK04_101146 CCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H09 compound treatment 499100.0 -29100.0 -0.25 349920.0 -129000.0 -1.1 -0.9502 -0.8455 3189513 PK04_101147 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H10 compound treatment 246990.0 -281000.0 -2.39 535880.0 56700.0 0.48 -1.3513 -0.5537 3189510 PK04_101148 CC(C)(CO)N1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H11 compound treatment 480480.0 -47700.0 -0.41 473330.0 -5810.0 -0.05 -0.3219 -0.7872 3069801 PK04_101149 OCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H12 compound treatment 535840.0 7640.0 0.06 341280.0 -138000.0 -1.17 -0.781 -0.6668 3189514 PK04_101150 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H13 compound treatment 449400.0 -78800.0 -0.67 376420.0 -103000.0 -0.87 -1.0902 -0.9916 3189515 PK04_101151 OCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H14 compound treatment 541010.0 12800.0 0.11 353280.0 -126000.0 -1.07 -0.6779 -0.6317 3189514 PK04_101152 CCCCCN(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)C(C)(C)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H15 compound treatment 466650.0 -61600.0 -0.52 400200.0 -78900.0 -0.67 -0.8438 -0.9926 3069802 PK04_101153 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H16 compound treatment 566560.0 38400.0 0.33 451120.0 -28000.0 -0.24 0.0627 0.1552 3189516 PK04_101154 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H17 compound treatment 416980.0 -111000.0 -0.95 438420.0 -40700.0 -0.35 -0.9133 -0.9067 3189517 PK04_101155 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H18 compound treatment 518940.0 -9260.0 -0.08 491200.0 12100.0 0.1 0.0166 0.1287 3189516 PK04_101156 CC(C)(C)N(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H19 mock treatment 578080.0 49900.0 0.42 360230.0 -119000.0 -1.01 -0.4132 -0.3776 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H20 mock treatment 590360.0 62200.0 0.53 361640.0 -117000.0 -1.0 -0.3309 -0.2933 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H21 compound treatment 464240.0 -64000.0 -0.54 284160.0 -195000.0 -1.65 -1.5543 -0.8927 3069803 PK04_101157 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H22 compound treatment 539040.0 10800.0 0.09 438580.0 -40600.0 -0.34 -0.1781 -0.5 3189518 PK04_101158 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H23 compound treatment 519090.0 -9110.0 -0.08 452370.0 -26800.0 -0.23 -0.2154 -0.8977 3069804 PK04_101159 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 H24 compound treatment 541130.0 12900.0 0.11 487580.0 8440.0 0.07 0.1284 0.9784 3189518 PK04_101160 COc1ccc(cc1)N(CC=C)C(=O)C2N(CCCCCCO)C(=O)C3C(C4OC23C=C4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I01 compound treatment 539900.0 11700.0 0.1 433120.0 -46000.0 -0.39 -0.2057 -0.5105 3189519 PK04_101161 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I02 compound treatment 523770.0 -4430.0 -0.04 445860.0 -33300.0 -0.28 -0.2263 -0.7945 3189520 PK04_101162 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I03 compound treatment 557920.0 29700.0 0.25 402100.0 -77000.0 -0.65 -0.2833 -0.4044 3069839 PK04_101163 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I04 compound treatment 488550.0 -39700.0 -0.34 537600.0 58500.0 0.5 0.1121 0.1869 3189521 PK04_101164 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I05 mock treatment 566040.0 37800.0 0.32 425370.0 -53800.0 -0.46 -0.0949 -0.17 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I06 mock treatment 568450.0 40200.0 0.34 527760.0 48600.0 0.41 0.5337 0.9957 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I07 compound treatment 400580.0 -128000.0 -1.09 508840.0 29700.0 0.25 -0.5896 -0.529 3069840 PK04_101165 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I08 compound treatment 330880.0 -197000.0 -1.68 490260.0 11100.0 0.09 -1.1203 -0.6663 3189522 PK04_101166 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I09 compound treatment 586750.0 58500.0 0.5 365510.0 -114000.0 -0.96 -0.3294 -0.3036 3189523 PK04_101167 OCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I10 compound treatment 591360.0 63200.0 0.54 487960.0 8820.0 0.07 0.4328 0.7979 3069841 PK04_101168 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I11 compound treatment 590010.0 61800.0 0.53 470900.0 -8240.0 -0.07 0.3224 0.6078 3189524 PK04_101169 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I12 compound treatment 545180.0 17000.0 0.14 422210.0 -56900.0 -0.48 -0.2393 -0.4749 3189640 PK04_101170 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I13 compound treatment 329980.0 -198000.0 -1.69 467730.0 -11400.0 -0.1 -1.2609 -0.7465 3069842 PK04_101171 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I14 compound treatment 528030.0 -174.0 0.0 494880.0 15700.0 0.13 0.0934 0.6992 3189641 PK04_101172 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I15 compound treatment 474400.0 -53800.0 -0.46 513710.0 34600.0 0.29 -0.1163 -0.2139 3069843 PK04_101173 OCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I16 compound treatment 446350.0 -81900.0 -0.7 399080.0 -80100.0 -0.68 -0.9726 -0.9999 3189642 PK04_101174 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I17 compound treatment 461920.0 -66300.0 -0.56 518210.0 39100.0 0.33 -0.1644 -0.2513 3069844 PK04_101175 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I18 compound treatment 570460.0 42300.0 0.36 450500.0 -28600.0 -0.24 0.0824 0.1899 3189643 PK04_101176 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I19 compound treatment 557630.0 29400.0 0.25 380810.0 -98300.0 -0.83 -0.4128 -0.474 3069845 PK04_101177 OCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I20 compound treatment 530590.0 2390.0 0.02 516260.0 37100.0 0.31 0.237 0.7511 3189644 PK04_101178 CC(C)C(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I21 mock treatment 557440.0 29200.0 0.25 458450.0 -20700.0 -0.18 0.0518 0.1701 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I22 mock treatment 496000.0 -32200.0 -0.27 465370.0 -13800.0 -0.12 -0.2763 -0.9278 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I23 compound treatment 511410.0 -16800.0 -0.14 506130.0 27000.0 0.23 0.0609 0.2256 3189645 PK04_101179 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 I24 compound treatment 357120.0 -171000.0 -1.46 478980.0 -159.0 0.0 -1.0301 -0.7078 3069846 PK04_101180 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J01 compound treatment 429800.0 -98400.0 -0.84 499860.0 20700.0 0.18 -0.4677 -0.5467 3189646 PK04_101181 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J02 compound treatment 570200.0 42000.0 0.36 539680.0 60500.0 0.51 0.6158 0.9843 3189647 PK04_101182 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J03 compound treatment 453290.0 -74900.0 -0.64 351790.0 -127000.0 -1.08 -1.2145 -0.9683 3069847 PK04_101183 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J04 compound treatment 500800.0 -27400.0 -0.23 488180.0 9040.0 0.08 -0.1106 -0.4507 3189647 PK04_101184 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)O)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J05 mock treatment 551320.0 23100.0 0.2 376160.0 -103000.0 -0.87 -0.4786 -0.5345 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J06 mock treatment 371040.0 -157000.0 -1.34 438620.0 -40500.0 -0.34 -1.1885 -0.8609 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J07 compound treatment 450720.0 -77500.0 -0.66 465020.0 -14100.0 -0.12 -0.5508 -0.8221 3189648 PK04_101185 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J08 compound treatment 607590.0 79400.0 0.68 287590.0 -192000.0 -1.62 -0.6714 -0.3816 3189649 PK04_101186 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J09 compound treatment 349160.0 -179000.0 -1.52 356480.0 -123000.0 -1.04 -1.8128 -0.9827 3069848 PK04_101187 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J10 compound treatment 572930.0 44700.0 0.38 501440.0 22300.0 0.19 0.4028 0.948 3189649 PK04_101188 CCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J11 compound treatment 427460.0 -101000.0 -0.86 399710.0 -79400.0 -0.67 -1.0825 -0.9929 3189650 PK04_101189 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J12 compound treatment 517400.0 -10800.0 -0.09 295880.0 -183000.0 -1.55 -1.1642 -0.7476 3189651 PK04_101190 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J13 compound treatment 332390.0 -196000.0 -1.67 520860.0 41700.0 0.35 -0.9277 -0.5447 3069849 PK04_101191 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J14 compound treatment 536820.0 8620.0 0.07 489600.0 10500.0 0.09 0.1146 0.9955 3189651 PK04_101192 CCCCCN(CC=C)C(=O)C1N(CCCCCCO)C(=O)C2C(C3OC12C=C3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J15 compound treatment 501150.0 -27100.0 -0.23 540060.0 60900.0 0.52 0.2027 0.3583 3189652 PK04_101193 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J16 compound treatment 370440.0 -158000.0 -1.34 382660.0 -96500.0 -0.82 -1.5277 -0.9719 3069850 PK04_101194 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J17 compound treatment 540020.0 11800.0 0.1 500160.0 21000.0 0.18 0.1972 0.9632 3189653 PK04_101195 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J18 compound treatment 597770.0 69600.0 0.59 424960.0 -54200.0 -0.46 0.0935 0.1248 3069850 PK04_101196 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J19 compound treatment 516490.0 -11700.0 -0.1 529600.0 50500.0 0.43 0.2322 0.5284 3189654 PK04_101197 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J20 compound treatment 530250.0 2050.0 0.02 509340.0 30200.0 0.26 0.1935 0.7534 3069851 PK04_101198 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J21 mock treatment 578400.0 50200.0 0.43 499770.0 20600.0 0.18 0.4257 0.9224 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J22 mock treatment 562370.0 34200.0 0.29 501760.0 22600.0 0.19 0.3412 0.9797 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J23 compound treatment 441570.0 -86600.0 -0.74 456960.0 -22200.0 -0.19 -0.6542 -0.86 3189655 PK04_101199 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 J24 compound treatment 499270.0 -28900.0 -0.25 526140.0 47000.0 0.4 0.1079 0.2302 3069851 PK04_101200 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2c(Cl)cccc2CO)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K01 compound treatment 439630.0 -88600.0 -0.75 583280.0 104000.0 0.88 0.0918 0.0791 3189656 PK04_101201 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K02 compound treatment 576640.0 48400.0 0.41 570740.0 91600.0 0.78 0.8408 0.956 3189657 PK04_101202 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K03 compound treatment 571840.0 43600.0 0.37 502750.0 23600.0 0.2 0.4041 0.9581 3069890 PK04_101203 CC(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K04 compound treatment 609600.0 81400.0 0.69 408930.0 -70200.0 -0.6 0.0685 0.075 3189658 PK04_101204 CC(C)C(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K05 compound treatment 488550.0 -39700.0 -0.34 463900.0 -15200.0 -0.13 -0.3299 -0.9133 3069891 PK04_101205 CCCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K06 compound treatment 514920.0 -13300.0 -0.11 255490.0 -224000.0 -1.9 -1.4214 -0.7479 3189659 PK04_101206 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(CO)C(C)C)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K07 mock treatment 524000.0 -4200.0 -0.04 469040.0 -10100.0 -0.09 -0.0859 -0.9249 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K08 mock treatment 331450.0 -197000.0 -1.67 552900.0 73800.0 0.63 -0.7412 -0.4148 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K09 compound treatment 551300.0 23100.0 0.2 498240.0 19100.0 0.16 0.2535 0.9954 3187684 PK04_101207 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCOC(=O)[C@@H]6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K10 compound treatment 611270.0 83100.0 0.71 496000.0 16900.0 0.14 0.6008 0.8333 3069892 PK04_101208 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K11 compound treatment 514190.0 -14000.0 -0.12 324800.0 -154000.0 -1.31 -1.0101 -0.7683 3187685 PK04_101209 CCCCN1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K12 compound treatment 463860.0 -64300.0 -0.55 495840.0 16700.0 0.14 -0.2869 -0.5074 3187686 PK04_101210 CC(C)C(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K13 compound treatment 414940.0 -113000.0 -0.96 570020.0 90900.0 0.77 -0.1362 -0.1104 3069893 PK04_101211 CC(C)(C)N1CC=CC23O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K14 compound treatment 542250.0 14000.0 0.12 279440.0 -200000.0 -1.69 -1.1133 -0.6556 3187687 PK04_101212 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K15 mock treatment 673600.0 145000.0 1.24 588640.0 110000.0 0.93 1.5314 0.99 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K16 mock treatment 596440.0 68200.0 0.58 490210.0 11100.0 0.09 0.4769 0.811 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K17 compound treatment 586880.0 58700.0 0.5 487250.0 8110.0 0.07 0.4016 0.797 3069894 PK04_101213 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K18 compound treatment 560160.0 32000.0 0.27 513760.0 34600.0 0.29 0.3999 0.9993 3187688 PK04_101214 CC(C)C(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K19 compound treatment 484430.0 -43800.0 -0.37 487380.0 8240.0 0.07 -0.2139 -0.5645 3069895 PK04_101215 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K20 compound treatment 506800.0 -21400.0 -0.18 571780.0 92600.0 0.79 0.4269 0.5292 3187689 PK04_101216 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(CO)C(C)C)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K21 compound treatment 566590.0 38400.0 0.33 568550.0 89400.0 0.76 0.7672 0.9291 3187690 PK04_101217 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCOC(=O)[C@@H]4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K22 compound treatment 478000.0 -50200.0 -0.43 436520.0 -42600.0 -0.36 -0.5576 -0.9966 3069896 PK04_101218 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K23 mock treatment 530170.0 1970.0 0.02 543520.0 64400.0 0.55 0.398 0.7284 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 K24 mock treatment 537620.0 9420.0 0.08 387410.0 -91700.0 -0.78 -0.4936 -0.631 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L01 compound treatment 470040.0 -58200.0 -0.49 360640.0 -118000.0 -1.01 -1.0607 -0.9467 3187691 PK04_101219 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L02 compound treatment 543380.0 15200.0 0.13 519540.0 40400.0 0.34 0.3336 0.911 3187692 PK04_101220 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L03 compound treatment 520120.0 -8080.0 -0.07 507760.0 28600.0 0.24 0.123 0.4876 3069897 PK04_101221 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L04 compound treatment 379130.0 -149000.0 -1.27 452660.0 -26500.0 -0.22 -1.0556 -0.8196 3187693 PK04_101222 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L05 compound treatment 553720.0 25500.0 0.22 491210.0 12100.0 0.1 0.2259 0.9412 3187694 PK04_101223 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L06 compound treatment 536040.0 7840.0 0.07 528290.0 49200.0 0.42 0.342 0.8099 3187693 PK04_101224 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L07 mock treatment 601070.0 72900.0 0.62 327930.0 -151000.0 -1.28 -0.4686 -0.329 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L08 mock treatment 458880.0 -69300.0 -0.59 542340.0 63200.0 0.54 -0.0379 -0.0476 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L09 compound treatment 492330.0 -35900.0 -0.31 449620.0 -29500.0 -0.25 -0.3929 -0.9952 3069898 PK04_101225 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L10 compound treatment 627280.0 99100.0 0.84 558690.0 79600.0 0.67 1.0732 0.9939 3187692 PK04_101226 OCc1cccc(Cl)c1N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L11 compound treatment 445470.0 -82700.0 -0.7 283430.0 -196000.0 -1.66 -1.6716 -0.927 3187695 PK04_101227 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L12 compound treatment 569350.0 41100.0 0.35 297140.0 -182000.0 -1.54 -0.8441 -0.5332 3187696 PK04_101228 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L13 compound treatment 515360.0 -12800.0 -0.11 315880.0 -163000.0 -1.38 -1.0565 -0.7605 3069899 PK04_101229 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@@H]3C2C(=O)O1)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L14 compound treatment 524450.0 -3750.0 -0.03 506290.0 27200.0 0.23 0.1403 0.6033 3187696 PK04_101230 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1c(Cl)cccc1CO)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L15 mock treatment 447700.0 -80500.0 -0.68 490400.0 11300.0 0.1 -0.4167 -0.6026 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L16 mock treatment 553020.0 24800.0 0.21 488450.0 9310.0 0.08 0.2051 0.91 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L17 compound treatment 538760.0 10600.0 0.09 485310.0 6170.0 0.05 0.1005 0.967 3187697 PK04_101231 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L18 compound treatment 523700.0 -4500.0 -0.04 539440.0 60300.0 0.51 0.3346 0.6523 3187698 PK04_101232 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L19 compound treatment 511780.0 -16400.0 -0.14 379950.0 -99200.0 -0.84 -0.6938 -0.8134 3069900 PK04_101233 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L20 compound treatment 541250.0 13000.0 0.11 430560.0 -48600.0 -0.41 -0.2129 -0.4989 3187698 PK04_101234 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L21 compound treatment 449280.0 -78900.0 -0.67 480410.0 1270.0 0.01 -0.4671 -0.6957 3187699 PK04_101235 CC1CC/C=C\[C@H]2OC34C=CCN(Cc5ccccc5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L22 compound treatment 475290.0 -52900.0 -0.45 516800.0 37700.0 0.32 -0.0924 -0.1674 3187700 PK04_101236 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L23 mock treatment 528710.0 506.0 0.0 531380.0 52200.0 0.44 0.3164 0.7139 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 L24 mock treatment 436410.0 -91800.0 -0.78 441760.0 -37400.0 -0.32 -0.7764 -0.9212 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M01 compound treatment 524860.0 -3340.0 -0.03 393860.0 -85300.0 -0.72 -0.5316 -0.7343 3187701 PK04_101237 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCOC(=O)[C@@H]5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M02 compound treatment 524610.0 -3590.0 -0.03 569610.0 90500.0 0.77 0.521 0.6784 3069926 PK04_101238 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M03 compound treatment 355450.0 -173000.0 -1.47 524590.0 45500.0 0.39 -0.7666 -0.5045 3187702 PK04_101239 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M04 compound treatment 539200.0 11000.0 0.09 519300.0 40200.0 0.34 0.307 0.8691 3069927 PK04_101240 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M05 compound treatment 550960.0 22800.0 0.19 547680.0 68500.0 0.58 0.548 0.8943 3187703 PK04_101241 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M06 compound treatment 485150.0 -43100.0 -0.37 466160.0 -13000.0 -0.11 -0.3368 -0.8807 3187824 PK04_101242 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCC(C)OC(=O)C6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M07 compound treatment 520670.0 -7530.0 -0.06 390330.0 -88800.0 -0.75 -0.578 -0.7645 3069928 PK04_101243 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M08 compound treatment 311450.0 -217000.0 -1.84 396130.0 -83000.0 -0.7 -1.8018 -0.9128 3187825 PK04_101244 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M09 mock treatment 543140.0 14900.0 0.13 536450.0 57300.0 0.49 0.4336 0.8629 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M10 mock treatment 546440.0 18200.0 0.16 579920.0 101000.0 0.85 0.7142 0.822 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M11 compound treatment 476100.0 -52100.0 -0.44 519970.0 40800.0 0.35 -0.0685 -0.1218 3187826 PK04_101245 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M12 compound treatment 375330.0 -153000.0 -1.3 506600.0 27500.0 0.23 -0.7549 -0.5714 3069929 PK04_101246 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M13 mock treatment 357000.0 -171000.0 -1.46 523260.0 44100.0 0.37 -0.7652 -0.5089 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M14 mock treatment 559880.0 31700.0 0.27 499550.0 20400.0 0.17 0.313 0.9771 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M15 compound treatment 577920.0 49700.0 0.42 506570.0 27400.0 0.23 0.4636 0.9604 3187827 PK04_101247 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M16 compound treatment 500980.0 -27200.0 -0.23 517210.0 38100.0 0.32 0.0646 0.1625 3187828 PK04_101248 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M17 compound treatment 585460.0 57300.0 0.49 457190.0 -21900.0 -0.19 0.2128 0.408 3069930 PK04_101249 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M18 compound treatment 545060.0 16900.0 0.14 449600.0 -29500.0 -0.25 -0.0758 -0.2625 3187829 PK04_101250 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M19 compound treatment 534080.0 5880.0 0.05 498010.0 18900.0 0.16 0.1485 0.8857 3069931 PK04_101251 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M20 compound treatment 570300.0 42100.0 0.36 488420.0 9280.0 0.08 0.3089 0.8424 3187830 PK04_101252 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M21 compound treatment 525340.0 -2860.0 -0.02 500640.0 21500.0 0.18 0.1117 0.6073 3187831 PK04_101253 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M22 compound treatment 516070.0 -12100.0 -0.1 517050.0 37900.0 0.32 0.1544 0.4572 3069932 PK04_101254 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M23 compound treatment 496070.0 -32100.0 -0.27 515430.0 36300.0 0.31 0.0244 0.0592 3187832 PK04_101255 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 M24 compound treatment 473860.0 -54300.0 -0.46 435060.0 -44100.0 -0.37 -0.5913 -0.9945 3187833 PK04_101256 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N01 compound treatment 355790.0 -172000.0 -1.47 516160.0 37000.0 0.31 -0.8151 -0.5434 3069933 PK04_101257 CC(C)N1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N02 compound treatment 549180.0 21000.0 0.18 560330.0 81200.0 0.69 0.6132 0.8619 3187700 PK04_101258 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c2ccc(CCO)cc2)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N03 compound treatment 573760.0 45600.0 0.39 521480.0 42300.0 0.36 0.528 0.9993 3187834 PK04_101259 CCCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N04 compound treatment 577650.0 49400.0 0.42 522400.0 43300.0 0.37 0.5569 0.9977 3069934 PK04_101260 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N05 compound treatment 490350.0 -37900.0 -0.32 485530.0 6390.0 0.05 -0.1894 -0.5799 3187835 PK04_101261 CC1CC/C=C\[C@H]2OC34C=CCN(Cn5nnc6ccccc56)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N06 compound treatment 541460.0 13300.0 0.11 532090.0 53000.0 0.45 0.3974 0.858 3069934 PK04_101262 OCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N07 compound treatment 543070.0 14900.0 0.13 502840.0 23700.0 0.2 0.2316 0.975 3187836 PK04_101263 CCCCN1CC=CC23O[C@@H]4/C=C\CCC(C)OC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N08 compound treatment 542720.0 14500.0 0.12 551120.0 72000.0 0.61 0.5191 0.8333 3069935 PK04_101264 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N09 mock treatment 586980.0 58800.0 0.5 321130.0 -158000.0 -1.34 -0.5942 -0.4154 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N10 mock treatment 503850.0 -24400.0 -0.21 596340.0 117000.0 0.99 0.5565 0.548 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N11 compound treatment 532550.0 4350.0 0.04 497540.0 18400.0 0.16 0.1365 0.8511 3187837 PK04_101265 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N12 compound treatment 597240.0 69000.0 0.59 533290.0 54200.0 0.46 0.7401 0.9926 3069935 PK04_101266 CCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N13 mock treatment 534420.0 6220.0 0.05 555710.0 76600.0 0.65 0.4967 0.7622 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N14 mock treatment 572730.0 44500.0 0.38 529760.0 50600.0 0.43 0.5715 0.998 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N15 compound treatment 551630.0 23400.0 0.2 556800.0 77700.0 0.66 0.6067 0.8816 3069936 PK04_101267 CC1CC/C=C\[C@H]2OC34C=CCN(CCN5CCOCC5)C(=O)[C@H]4N(CCCCCCO)C(=O)[C@@H]3C2C(=O)O1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N16 compound treatment 580330.0 52100.0 0.44 508320.0 29200.0 0.25 0.4886 0.9621 3187838 PK04_101268 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N17 compound treatment 554350.0 26100.0 0.22 499490.0 20400.0 0.17 0.2794 0.9921 3187839 PK04_101269 CC1CC/C=C\[C@H]2OC34C=CCN(C(=O)[C@H]4N(CCCCCCO)C(=O)[C@]3(C)C2C(=O)O1)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N18 compound treatment 598360.0 70200.0 0.6 498570.0 19400.0 0.16 0.5386 0.8698 3187838 PK04_101270 CCCCCN(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)c1ccc(CCO)cc1)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N19 compound treatment 504930.0 -23300.0 -0.2 521840.0 42700.0 0.36 0.1161 0.2813 3187840 PK04_101271 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCC(C)OC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N20 compound treatment 548570.0 20400.0 0.17 552640.0 73500.0 0.62 0.5634 0.8706 3187841 PK04_101272 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N21 compound treatment 505990.0 -22200.0 -0.19 477290.0 -1850.0 -0.02 -0.1447 -0.7632 3069973 PK04_101273 OCCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N22 compound treatment 397710.0 -130000.0 -1.11 518330.0 39200.0 0.33 -0.5499 -0.4745 3187841 PK04_101274 CC(C)(C)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N23 compound treatment 533480.0 5280.0 0.04 488370.0 9230.0 0.08 0.0871 0.9651 3187842 PK04_101275 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 N24 compound treatment 463130.0 -65100.0 -0.55 512990.0 33900.0 0.29 -0.1884 -0.3021 3187843 PK04_101276 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O01 compound treatment 474080.0 -54100.0 -0.46 407120.0 -72000.0 -0.61 -0.7576 -0.9903 3069974 PK04_101277 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O02 compound treatment 476740.0 -51500.0 -0.44 469120.0 -10000.0 -0.08 -0.3697 -0.8289 3187957 PK04_101278 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O03 compound treatment 464200.0 -64000.0 -0.54 487360.0 8220.0 0.07 -0.3357 -0.6116 3187958 PK04_101279 OCCCCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O04 compound treatment 400610.0 -128000.0 -1.09 343460.0 -136000.0 -1.15 -1.5814 -0.9996 3069975 PK04_101280 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O05 compound treatment 451450.0 -76800.0 -0.65 517440.0 38300.0 0.32 -0.232 -0.3181 3187959 PK04_101281 CC(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O06 compound treatment 501830.0 -26400.0 -0.22 493010.0 13900.0 0.12 -0.0755 -0.2978 3187960 PK04_101282 CC(CO)N1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O07 compound treatment 436930.0 -91300.0 -0.78 442680.0 -36500.0 -0.31 -0.7678 -0.9186 3069976 PK04_101283 CCCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O08 compound treatment 443260.0 -84900.0 -0.72 296600.0 -183000.0 -1.55 -1.6059 -0.9398 3187961 PK04_101284 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(C(C)CO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O09 compound treatment 453680.0 -74500.0 -0.63 421390.0 -57700.0 -0.49 -0.7947 -0.9919 3069977 PK04_101285 OCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6C=CCCOC(=O)C6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O10 compound treatment 447550.0 -80700.0 -0.69 423150.0 -56000.0 -0.47 -0.821 -0.9839 3187962 PK04_101286 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O11 mock treatment 472930.0 -55300.0 -0.47 536420.0 57300.0 0.49 0.0111 0.0164 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O12 mock treatment 565290.0 37100.0 0.32 362260.0 -117000.0 -0.99 -0.478 -0.4594 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O13 compound treatment 264760.0 -263000.0 -2.24 449570.0 -29600.0 -0.25 -1.7621 -0.7814 3187963 PK04_101287 CCCCN1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O14 compound treatment 480770.0 -47400.0 -0.4 432610.0 -46500.0 -0.39 -0.5644 -0.9999 3069978 PK04_101288 CC(CO)N1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O15 compound treatment 535550.0 7350.0 0.06 338650.0 -140000.0 -1.19 -0.7985 -0.6691 3187964 PK04_101289 CC(C)(C)N1CC=CC23O[C@@H]4C=CCCOC(=O)C4[C@H]3C(=O)N(CCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O16 compound treatment 494520.0 -33700.0 -0.29 429940.0 -49200.0 -0.42 -0.4977 -0.9832 3187965 PK04_101290 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O17 compound treatment 457890.0 -70300.0 -0.6 415360.0 -63800.0 -0.54 -0.8055 -0.9987 3069979 PK04_101291 OCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5C=CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O18 compound treatment 462560.0 -65600.0 -0.56 405120.0 -74000.0 -0.63 -0.8389 -0.9983 3187966 PK04_101292 CC(CO)N1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@@]3(C)C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O19 compound treatment 492160.0 -36000.0 -0.31 432160.0 -47000.0 -0.4 -0.4986 -0.9916 3187967 PK04_101293 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O20 compound treatment 470530.0 -57700.0 -0.49 427080.0 -52100.0 -0.44 -0.6592 -0.9986 3069980 PK04_101294 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(C(C)CO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O21 compound treatment 470960.0 -57200.0 -0.49 499060.0 19900.0 0.17 -0.2249 -0.4362 3187968 PK04_101295 OCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4C=CCCOC(=O)C4[C@H]3C1=O)c5ccc(Cl)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O22 compound treatment 402340.0 -126000.0 -1.07 447100.0 -32000.0 -0.27 -0.9493 -0.8593 3069981 PK04_101296 OCCN1[C@@H]2C(=O)N(Cc3ccccc3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O23 compound treatment 498180.0 -30000.0 -0.26 476050.0 -3090.0 -0.03 -0.1991 -0.7756 3187969 PK04_101297 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5C=CCCOC(=O)C5[C@H]4C(=O)N(CCCCCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 O24 compound treatment 363380.0 -165000.0 -1.4 345220.0 -134000.0 -1.14 -1.7948 -0.9945 3187970 PK04_101298 CC(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P01 compound treatment 353350.0 -175000.0 -1.49 329760.0 -149000.0 -1.27 -1.9478 -0.9968 3069982 PK04_101299 CCCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P02 compound treatment 374370.0 -154000.0 -1.31 284490.0 -195000.0 -1.65 -2.0929 -0.9934 3187843 PK04_101300 COc1ccc(cc1)N(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P03 compound treatment 267780.0 -260000.0 -2.22 273720.0 -205000.0 -1.74 -2.7987 -0.9929 3187971 PK04_101301 OCCCCCCN1[C@@H]2C(=O)N(Cn3nnc4ccccc34)CC=CC52O[C@@H]6/C=C\CCCOC(=O)C6[C@H]5C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P04 compound treatment 418670.0 -110000.0 -0.93 371680.0 -107000.0 -0.91 -1.3035 -0.9999 3069983 PK04_101302 OCCOCCN(C(C(=O)N(CC=C)Cc1ccccc1)c2cccs2)C(=O)/C=C\C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P05 compound treatment 336410.0 -192000.0 -1.63 297530.0 -182000.0 -1.54 -2.2431 -0.9996 3187972 PK04_101303 CCCCN1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P06 compound treatment 410080.0 -118000.0 -1.0 364490.0 -115000.0 -0.97 -1.3983 -0.9999 3187973 PK04_101304 OCCOCCc1ccc(cc1)N(C(C(=O)N(CC=C)Cc2ccccc2)c3cccs3)C(=O)/C=C\C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P07 compound treatment 268120.0 -260000.0 -2.21 325920.0 -153000.0 -1.3 -2.4836 -0.9678 3069985 PK04_101305 CC(C)(C)N1CC=CC23O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C(=O)N(CCCCCCO)[C@@H]2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P08 compound treatment 290040.0 -238000.0 -2.03 373550.0 -106000.0 -0.9 -2.066 -0.9326 3187974 PK04_101306 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P09 compound treatment 398830.0 -129000.0 -1.1 207060.0 -272000.0 -2.31 -2.4102 -0.9426 3187975 PK04_101307 OCCCCCCN1[C@@H]2C(=O)N(CCN3CCOCC3)CC=CC42O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P10 compound treatment 387490.0 -141000.0 -1.2 303640.0 -175000.0 -1.49 -1.8991 -0.9942 3187974 PK04_101308 CCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P11 mock treatment 380160.0 -148000.0 -1.26 221020.0 -258000.0 -2.19 -2.4388 -0.9655 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P12 mock treatment 248640.0 -280000.0 -2.38 258650.0 -220000.0 -1.87 -3.0043 -0.9929 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P13 compound treatment 198330.0 -330000.0 -2.81 187200.0 -292000.0 -2.48 -3.7355 -0.9981 3069986 PK04_101309 OCCCCCCN1[C@@H]2C(=O)N(CC=CC32O[C@@H]4/C=C\CCCOC(=O)C4[C@H]3C1=O)c5ccc6ccccc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P14 compound treatment 313300.0 -215000.0 -1.83 274650.0 -204000.0 -1.73 -2.5193 -0.9997 3069301 PK04_101310 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P15 compound treatment 294830.0 -233000.0 -1.99 322180.0 -157000.0 -1.33 -2.3453 -0.9811 3187976 PK04_101311 C[C@]12C3[C@H](OC24C=CCN(C(=O)[C@H]4N(CCCCCCO)C1=O)c5ccc(Cl)cc5)/C=C\CCCOC3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P16 compound treatment 367630.0 -161000.0 -1.37 247540.0 -232000.0 -1.96 -2.3551 -0.9842 3069301 PK04_101312 CCCCCN(CC=C)C(=O)C(N(CCOCCO)C(=O)/C=C\C(=O)O)c1cccs1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P17 compound treatment 265630.0 -263000.0 -2.23 293290.0 -186000.0 -1.58 -2.6943 -0.9854 3187977 PK04_101313 CCN(CC)c1ccc(cc1)N2CC=CC34O[C@@H]5/C=C\CCCOC(=O)C5[C@H]4C(=O)N(CCCCCCO)[C@@H]3C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P18 compound treatment 312110.0 -216000.0 -1.84 399160.0 -80000.0 -0.68 -1.7797 -0.9082 3069302 PK04_101314 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P19 compound treatment 196800.0 -331000.0 -2.82 372700.0 -106000.0 -0.9 -2.632 -0.8891 3189130 PK04_101315 CC(C)(C)N(CC=C)C(=O)C1N(C(=O)C2C(C3OC12C=C3)C(=O)O)c4c(Cl)cccc4CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P20 compound treatment 370720.0 -157000.0 -1.34 406510.0 -72600.0 -0.62 -1.383 -0.9379 3069302 PK04_101316 CC(C)(C)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c1cccs1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P21 compound treatment 334570.0 -194000.0 -1.65 272850.0 -206000.0 -1.75 -2.4022 -0.9995 3189131 PK04_101317 COc1ccc(cc1)N(CC=C)C(=O)C2N(C(=O)C3C(C4OC23C=C4)C(=O)O)c5c(Cl)cccc5CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P22 compound treatment 327120.0 -201000.0 -1.71 333050.0 -146000.0 -1.24 -2.0859 -0.9875 3069303 PK04_101318 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P23 compound treatment 318440.0 -210000.0 -1.78 231220.0 -248000.0 -2.1 -2.7489 -0.9967 3069685 PK04_101319 OCc1cccc(Cl)c1N2C(C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)C(C5C(=O)O)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2101 P24 compound treatment 296830.0 -231000.0 -1.97 203680.0 -275000.0 -2.34 -3.0441 -0.9964 3069303 PK04_101320 COc1ccc(cc1)N(CC=C)C(=O)C(N(C(=O)/C=C\C(=O)O)C(C)(C)CO)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A01 compound treatment 249470.0 -212000.0 -1.81 329440.0 -110000.0 -0.93 -1.9369 -0.9528 3188092 PK04_102001 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A02 compound treatment 136000.0 -326000.0 -2.77 111640.0 -328000.0 -2.78 -3.9259 -1.0 3188093 PK04_102002 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A03 compound treatment 333460.0 -128000.0 -1.09 168650.0 -271000.0 -2.3 -2.3961 -0.9421 3069304 PK04_102003 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccccc43 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A04 compound treatment 172590.0 -289000.0 -2.46 191170.0 -248000.0 -2.11 -3.2287 -0.997 3188094 PK04_102004 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A05 compound treatment 367240.0 -94500.0 -0.8 363520.0 -75900.0 -0.64 -1.024 -0.994 3069305 PK04_102005 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A06 compound treatment 390720.0 -71000.0 -0.6 253300.0 -186000.0 -1.58 -1.5439 -0.9131 3188095 PK04_102006 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A07 compound treatment 190590.0 -271000.0 -2.31 320360.0 -119000.0 -1.01 -2.3456 -0.9314 3069306 PK04_102007 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A08 compound treatment 109160.0 -353000.0 -3.0 120860.0 -319000.0 -2.7 -4.032 -0.9986 3188096 PK04_102008 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A09 compound treatment 308910.0 -153000.0 -1.3 352000.0 -87500.0 -0.74 -1.444 -0.9646 3188097 PK04_102009 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A10 compound treatment 175040.0 -287000.0 -2.44 152640.0 -287000.0 -2.43 -3.4451 -1.0 3069307 PK04_102010 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A11 compound treatment 459210.0 -2540.0 -0.02 401610.0 -37900.0 -0.32 -0.2423 -0.7529 3188098 PK04_102011 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A12 compound treatment 152260.0 -309000.0 -2.63 186290.0 -253000.0 -2.15 -3.3803 -0.9949 3069308 PK04_102012 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A13 mock treatment 403910.0 -57800.0 -0.49 335590.0 -104000.0 -0.88 -0.971 -0.9621 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A14 mock treatment 478130.0 16400.0 0.14 395490.0 -44000.0 -0.37 -0.1652 -0.4149 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A15 compound treatment 280760.0 -181000.0 -1.54 221250.0 -218000.0 -1.85 -2.3976 -0.9958 3188099 PK04_102013 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A16 compound treatment 273210.0 -189000.0 -1.6 249120.0 -190000.0 -1.61 -2.2759 -1.0 3188100 PK04_102014 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A17 compound treatment 159470.0 -302000.0 -2.57 182770.0 -257000.0 -2.18 -3.3581 -0.9966 3069309 PK04_102015 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@]5(O[C@H](CCO)[C@H]([C@@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A18 compound treatment 159800.0 -302000.0 -2.57 210630.0 -229000.0 -1.94 -3.189 -0.9905 3188101 PK04_102016 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A19 compound treatment 147290.0 -314000.0 -2.68 204340.0 -235000.0 -1.99 -3.3019 -0.9895 3069310 PK04_102017 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A20 compound treatment 172230.0 -290000.0 -2.46 201940.0 -238000.0 -2.01 -3.1663 -0.995 3188102 PK04_102018 COc1ccc(cc1)C(=O)Nc2ccc3N(Cc4ccccc4)C(=O)[C@@]5(O[C@@H](CCO)[C@@H]([C@H]5C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A21 compound treatment 279760.0 -182000.0 -1.55 456570.0 17100.0 0.15 -0.9921 -0.638 3188103 PK04_102019 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A22 compound treatment 111290.0 -350000.0 -2.98 136020.0 -303000.0 -2.57 -3.9283 -0.9973 3069311 PK04_102020 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(NC(=O)[C@H](C)O)cc4)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A23 compound treatment 424050.0 -37700.0 -0.32 433760.0 -5700.0 -0.05 -0.261 -0.8047 3188104 PK04_102021 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 A24 compound treatment 331080.0 -131000.0 -1.11 210240.0 -229000.0 -1.94 -2.161 -0.9648 3188105 PK04_102022 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCOC7=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B01 compound treatment 442630.0 -19100.0 -0.16 438410.0 -1050.0 -0.01 -0.1213 -0.7449 3069350 PK04_102023 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B02 compound treatment 218990.0 -243000.0 -2.07 246350.0 -193000.0 -1.64 -2.6186 -0.9934 3188106 PK04_102024 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B03 compound treatment 449940.0 -11800.0 -0.1 386850.0 -52600.0 -0.45 -0.3866 -0.8451 3069351 PK04_102025 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCCCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B04 compound treatment 443120.0 -18600.0 -0.16 342090.0 -97400.0 -0.83 -0.6961 -0.8277 3188107 PK04_102026 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B05 compound treatment 431560.0 -30200.0 -0.26 433280.0 -6180.0 -0.05 -0.2187 -0.8343 3188221 PK04_102027 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B06 compound treatment 412800.0 -48900.0 -0.42 241930.0 -198000.0 -1.68 -1.4793 -0.8568 3069352 PK04_102028 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B07 compound treatment 362900.0 -98800.0 -0.84 319840.0 -120000.0 -1.01 -1.3121 -0.9956 3188222 PK04_102029 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B08 compound treatment 431370.0 -30400.0 -0.26 257010.0 -182000.0 -1.55 -1.2771 -0.8139 3069353 PK04_102030 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B09 compound treatment 497440.0 35700.0 0.3 383050.0 -56400.0 -0.48 -0.1237 -0.2182 3188223 PK04_102031 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B10 compound treatment 391290.0 -70500.0 -0.6 273960.0 -166000.0 -1.4 -1.4166 -0.928 3188224 PK04_102032 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B11 compound treatment 465330.0 3580.0 0.03 455760.0 16300.0 0.14 0.1193 0.8428 3069354 PK04_102033 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B12 compound treatment 300530.0 -161000.0 -1.37 256650.0 -183000.0 -1.55 -2.0664 -0.9981 3188225 PK04_102034 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B13 mock treatment 480480.0 18700.0 0.16 416810.0 -22700.0 -0.19 -0.0232 -0.0929 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B14 mock treatment 474210.0 12500.0 0.11 440190.0 726.0 0.01 0.0793 0.7469 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B15 compound treatment 366890.0 -94900.0 -0.81 257480.0 -182000.0 -1.54 -1.6622 -0.9542 3188226 PK04_102035 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B16 compound treatment 268960.0 -193000.0 -1.64 381830.0 -57600.0 -0.49 -1.5054 -0.8796 3069355 PK04_102036 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B17 compound treatment 309920.0 -152000.0 -1.29 369780.0 -69700.0 -0.59 -1.3313 -0.9372 3188227 PK04_102037 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B18 compound treatment 321860.0 -140000.0 -1.19 313780.0 -126000.0 -1.07 -1.5954 -0.9985 3069356 PK04_102038 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(I)c5)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B19 compound treatment 476200.0 14500.0 0.12 408320.0 -31100.0 -0.26 -0.0999 -0.3427 3188228 PK04_102039 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B20 compound treatment 414400.0 -47300.0 -0.4 386760.0 -52700.0 -0.45 -0.6009 -0.9986 3188229 PK04_102040 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B21 compound treatment 402670.0 -59100.0 -0.5 464430.0 25000.0 0.21 -0.2056 -0.377 3069357 PK04_102041 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B22 compound treatment 362750.0 -99000.0 -0.84 320930.0 -119000.0 -1.01 -1.3065 -0.9961 3188230 PK04_102042 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(I)c6)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B23 compound treatment 272960.0 -189000.0 -1.61 381670.0 -57800.0 -0.49 -1.4823 -0.8827 3069358 PK04_102043 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 B24 compound treatment 385490.0 -76300.0 -0.65 473180.0 33700.0 0.29 -0.2565 -0.3618 3188231 PK04_102044 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(I)cc5)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C01 compound treatment 414400.0 -47300.0 -0.4 442730.0 3270.0 0.03 -0.2652 -0.6569 3188232 PK04_102045 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C02 compound treatment 154600.0 -307000.0 -2.61 183720.0 -256000.0 -2.17 -3.3817 -0.9957 3069359 PK04_102046 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C03 compound treatment 309190.0 -153000.0 -1.3 313700.0 -126000.0 -1.07 -1.6721 -0.9953 3188233 PK04_102047 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C04 compound treatment 426660.0 -35100.0 -0.3 361060.0 -78400.0 -0.67 -0.6813 -0.9346 3188234 PK04_102048 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C05 compound treatment 399580.0 -62200.0 -0.53 366330.0 -73100.0 -0.62 -0.8126 -0.9968 3069360 PK04_102049 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C06 compound treatment 9490.0 -452000.0 -3.85 5690.0 -434000.0 -3.68 -5.3224 -0.9998 3188235 PK04_102050 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C07 compound treatment 437720.0 -24000.0 -0.2 287370.0 -152000.0 -1.29 -1.0568 -0.809 3069393 PK04_102051 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C08 compound treatment 339920.0 -122000.0 -1.04 337920.0 -102000.0 -0.86 -1.3419 -0.9958 3188236 PK04_102052 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C09 compound treatment 329600.0 -132000.0 -1.12 269240.0 -170000.0 -1.44 -1.816 -0.9923 3069394 PK04_102053 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C10 compound treatment 92960.0 -369000.0 -3.14 104130.0 -335000.0 -2.84 -4.2298 -0.9988 3188352 PK04_102054 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C11 mock treatment 432680.0 -29100.0 -0.25 408640.0 -30800.0 -0.26 -0.3597 -0.9996 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C12 mock treatment 409440.0 -52300.0 -0.44 382790.0 -56700.0 -0.48 -0.6546 -0.9993 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C13 compound treatment 416320.0 -45400.0 -0.39 423860.0 -15600.0 -0.13 -0.3669 -0.8981 3188353 PK04_102055 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C14 compound treatment 72180.0 -390000.0 -3.31 135230.0 -304000.0 -2.58 -4.1683 -0.9923 3069395 PK04_102056 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C15 mock treatment 392380.0 -69400.0 -0.59 429030.0 -10400.0 -0.09 -0.4799 -0.8042 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C16 mock treatment 408320.0 -53400.0 -0.45 399890.0 -39600.0 -0.34 -0.5588 -0.9889 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C17 compound treatment 207360.0 -254000.0 -2.16 109510.0 -330000.0 -2.8 -3.5094 -0.9919 3188354 PK04_102057 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C18 compound treatment 243400.0 -218000.0 -1.86 187300.0 -252000.0 -2.14 -2.826 -0.9975 3069396 PK04_102058 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C19 compound treatment 72860.0 -389000.0 -3.31 89290.0 -350000.0 -2.97 -4.4398 -0.9986 3188355 PK04_102059 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C20 compound treatment 125570.0 -336000.0 -2.86 129710.0 -310000.0 -2.63 -3.8802 -0.9991 3188356 PK04_102060 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C21 compound treatment 215160.0 -247000.0 -2.1 247200.0 -192000.0 -1.63 -2.6366 -0.9923 3069397 PK04_102061 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C22 compound treatment 247740.0 -214000.0 -1.82 205920.0 -234000.0 -1.98 -2.6882 -0.9991 3188357 PK04_102062 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)COc7ccccc67 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C23 compound treatment 196640.0 -265000.0 -2.26 231840.0 -208000.0 -1.76 -2.8401 -0.9925 3188358 PK04_102063 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 C24 compound treatment 203890.0 -258000.0 -2.19 180810.0 -259000.0 -2.19 -3.1026 -1.0 3069398 PK04_102064 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D01 compound treatment 264480.0 -197000.0 -1.68 336010.0 -103000.0 -0.88 -1.8072 -0.9543 3188359 PK04_102065 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D02 compound treatment 217380.0 -244000.0 -2.08 292580.0 -147000.0 -1.25 -2.351 -0.97 3069399 PK04_102066 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(I)cc6)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D03 compound treatment 297640.0 -164000.0 -1.4 395490.0 -44000.0 -0.37 -1.251 -0.8657 3188360 PK04_102067 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D04 compound treatment 413290.0 -48500.0 -0.41 411700.0 -27800.0 -0.24 -0.458 -0.9647 3188361 PK04_102068 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D05 compound treatment 424510.0 -37200.0 -0.32 329960.0 -110000.0 -0.93 -0.8808 -0.8975 3069400 PK04_102069 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D06 compound treatment 353480.0 -108000.0 -0.92 312480.0 -127000.0 -1.08 -1.413 -0.997 3188362 PK04_102070 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D07 compound treatment 511870.0 50100.0 0.43 497070.0 57600.0 0.49 0.6471 0.9977 3188363 PK04_102071 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D08 compound treatment 468530.0 6780.0 0.06 450350.0 10900.0 0.09 0.1061 0.9744 3069401 PK04_102072 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D09 compound treatment 337760.0 -124000.0 -1.05 321120.0 -118000.0 -1.0 -1.4557 -0.9997 3188364 PK04_102073 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D10 compound treatment 404530.0 -57200.0 -0.49 421170.0 -18300.0 -0.16 -0.4539 -0.8885 3069402 PK04_102074 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D11 mock treatment 493570.0 31800.0 0.27 415040.0 -24400.0 -0.21 0.0449 0.1318 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D12 mock treatment 483000.0 21300.0 0.18 391760.0 -47700.0 -0.4 -0.1583 -0.3571 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D13 compound treatment 473550.0 11800.0 0.1 400870.0 -38600.0 -0.33 -0.1605 -0.4686 3069403 PK04_102075 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D14 compound treatment 289810.0 -172000.0 -1.46 212960.0 -227000.0 -1.92 -2.3929 -0.9909 3188365 PK04_102076 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D15 mock treatment 438950.0 -22800.0 -0.19 467370.0 27900.0 0.24 0.0303 0.0989 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D16 mock treatment 416260.0 -45500.0 -0.39 451400.0 11900.0 0.1 -0.202 -0.5051 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D17 compound treatment 363460.0 -98300.0 -0.84 390970.0 -48500.0 -0.41 -0.8821 -0.9466 3188366 PK04_102077 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D18 compound treatment 351310.0 -110000.0 -0.94 324600.0 -115000.0 -0.97 -1.3533 -0.9998 3069404 PK04_102078 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D19 compound treatment 413120.0 -48600.0 -0.41 288860.0 -151000.0 -1.28 -1.1959 -0.8905 3188367 PK04_102079 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D20 compound treatment 30850.0 -431000.0 -3.67 56360.0 -383000.0 -3.25 -4.89 -0.9982 3069405 PK04_102080 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D21 compound treatment 406880.0 -54900.0 -0.47 244120.0 -195000.0 -1.66 -1.5018 -0.8723 3188368 PK04_102081 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D22 compound treatment 354030.0 -108000.0 -0.92 374650.0 -64800.0 -0.55 -1.0367 -0.9701 3069440 PK04_102082 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D23 compound treatment 282990.0 -179000.0 -1.52 375520.0 -63900.0 -0.54 -1.4589 -0.9036 3188485 PK04_102083 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 D24 compound treatment 349240.0 -113000.0 -0.96 402590.0 -36900.0 -0.31 -0.898 -0.8918 3069441 PK04_102084 O[C@H](CC=C)c1ccc(O)c(F)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E01 mock treatment 504250.0 42500.0 0.36 453560.0 14100.0 0.12 0.3402 0.8934 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E02 mock treatment 473920.0 12200.0 0.1 354560.0 -84900.0 -0.72 -0.436 -0.5993 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E03 compound treatment 466740.0 4990.0 0.04 350590.0 -88900.0 -0.75 -0.503 -0.6662 3069442 PK04_102085 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(c6ccccc63)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E04 compound treatment 194320.0 -267000.0 -2.28 203960.0 -236000.0 -2.0 -3.0213 -0.9979 3188486 PK04_102086 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E05 compound treatment 290900.0 -171000.0 -1.45 270940.0 -169000.0 -1.43 -2.0386 -1.0 3188487 PK04_102087 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(c6ccccc63)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E06 compound treatment 389760.0 -72000.0 -0.61 312830.0 -127000.0 -1.07 -1.1926 -0.9645 3069443 PK04_102088 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E07 compound treatment 291930.0 -170000.0 -1.44 204000.0 -235000.0 -2.0 -2.4339 -0.9874 3188488 PK04_102089 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(c5ccccc53)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E08 compound treatment 265440.0 -196000.0 -1.67 143750.0 -296000.0 -2.51 -2.9546 -0.9805 3188489 PK04_102090 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E09 mock treatment 455700.0 -6050.0 -0.05 453150.0 13700.0 0.12 0.0457 0.3601 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E10 mock treatment 484210.0 22500.0 0.19 470620.0 31200.0 0.26 0.322 0.9873 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E11 compound treatment 342180.0 -120000.0 -1.02 294680.0 -145000.0 -1.23 -1.5877 -0.9956 3069444 PK04_102091 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E12 compound treatment 153230.0 -309000.0 -2.62 168810.0 -271000.0 -2.3 -3.4793 -0.9978 3188490 PK04_102092 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E13 compound treatment 325620.0 -136000.0 -1.16 258730.0 -181000.0 -1.53 -1.9029 -0.9904 3069445 PK04_102093 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E14 compound treatment 188280.0 -273000.0 -2.33 167680.0 -272000.0 -2.31 -3.2753 -1.0 3188491 PK04_102094 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N(C=O)c5ccccc5)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E15 compound treatment 311010.0 -151000.0 -1.28 276440.0 -163000.0 -1.38 -1.8846 -0.9993 3188492 PK04_102095 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E16 compound treatment 462320.0 575.0 0.0 432420.0 -7040.0 -0.06 -0.0388 -0.6471 3069446 PK04_102096 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E17 mock treatment 450990.0 -10800.0 -0.09 460810.0 21300.0 0.18 0.0633 0.3122 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E18 mock treatment 417340.0 -44400.0 -0.38 387300.0 -52200.0 -0.44 -0.58 -0.9969 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E19 compound treatment 311940.0 -150000.0 -1.27 276810.0 -163000.0 -1.38 -1.8768 -0.9992 3188493 PK04_102097 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E20 compound treatment 430960.0 -30800.0 -0.26 360070.0 -79400.0 -0.67 -0.6614 -0.9153 3188494 PK04_102098 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E21 compound treatment 214250.0 -247000.0 -2.11 218370.0 -221000.0 -1.88 -2.815 -0.9983 3069448 PK04_102099 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E22 compound treatment 221640.0 -240000.0 -2.04 350610.0 -88900.0 -0.75 -1.9773 -0.9082 3188495 PK04_102100 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E23 compound treatment 162000.0 -300000.0 -2.55 156000.0 -283000.0 -2.4 -3.5034 -0.9996 3069450 PK04_102101 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCOC5=O)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 E24 compound treatment 227050.0 -235000.0 -2.0 260680.0 -179000.0 -1.52 -2.4842 -0.9908 3188496 PK04_102102 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F01 mock treatment 477720.0 16000.0 0.14 418340.0 -21100.0 -0.18 -0.0306 -0.1361 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F02 mock treatment 492760.0 31000.0 0.26 250480.0 -189000.0 -1.6 -0.947 -0.5829 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F03 compound treatment 443620.0 -18100.0 -0.15 350680.0 -88800.0 -0.75 -0.6416 -0.8346 3188497 PK04_102103 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F04 compound treatment 208830.0 -253000.0 -2.15 149120.0 -290000.0 -2.46 -3.263 -0.9977 3069264 PK04_102104 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F05 compound treatment 415050.0 -46700.0 -0.4 319920.0 -120000.0 -1.01 -0.9979 -0.9163 3069265 PK04_102105 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F06 compound treatment 210200.0 -252000.0 -2.14 117200.0 -322000.0 -2.73 -3.4462 -0.9927 3188498 PK04_102106 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F07 compound treatment 159000.0 -303000.0 -2.58 189460.0 -250000.0 -2.12 -3.3208 -0.9953 3188499 PK04_102107 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCC5=O)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F08 compound treatment 417180.0 -44600.0 -0.38 330780.0 -109000.0 -0.92 -0.92 -0.9229 3069441 PK04_102108 O[C@H](CC=C)c1ccc(O)c(F)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F09 mock treatment 455590.0 -6160.0 -0.05 519790.0 80300.0 0.68 0.4448 0.6508 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F10 mock treatment 480970.0 19200.0 0.16 472480.0 33000.0 0.28 0.3137 0.9672 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F11 compound treatment 368570.0 -93200.0 -0.79 352420.0 -87000.0 -0.74 -1.0826 -0.9994 3188500 PK04_102109 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F12 compound treatment 492960.0 31200.0 0.27 395390.0 -44100.0 -0.37 -0.0766 -0.167 3069270 PK04_102110 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F13 compound treatment 392040.0 -69700.0 -0.59 229240.0 -210000.0 -1.78 -1.6803 -0.8941 3188501 PK04_102111 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F14 compound treatment 398080.0 -63700.0 -0.54 375680.0 -63800.0 -0.54 -0.7656 -1.0 3188502 PK04_102112 CSc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F15 compound treatment 455680.0 -6070.0 -0.05 329980.0 -109000.0 -0.93 -0.6932 -0.7452 3188623 PK04_102113 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F16 compound treatment 416520.0 -45200.0 -0.38 292910.0 -147000.0 -1.24 -1.1511 -0.8846 3069312 PK04_102114 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F17 mock treatment 479250.0 17500.0 0.15 348000.0 -91500.0 -0.78 -0.4433 -0.5611 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F18 mock treatment 444970.0 -16800.0 -0.14 514150.0 74700.0 0.63 0.3471 0.5344 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F19 compound treatment 358360.0 -103000.0 -0.88 379840.0 -59600.0 -0.51 -0.9796 -0.9655 3188624 PK04_102115 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F20 compound treatment 337290.0 -124000.0 -1.06 495140.0 55700.0 0.47 -0.4147 -0.3577 3069314 PK04_102116 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F21 compound treatment 389190.0 -72600.0 -0.62 403640.0 -35800.0 -0.3 -0.6513 -0.9467 3069316 PK04_102117 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7CCC7=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F22 compound treatment 254850.0 -207000.0 -1.76 204060.0 -235000.0 -2.0 -2.6566 -0.998 3188625 PK04_102118 O[C@@H](CC=C)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F23 compound treatment 325540.0 -136000.0 -1.16 409160.0 -30300.0 -0.26 -1.0011 -0.8435 3188626 PK04_102119 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 F24 compound treatment 419380.0 -42400.0 -0.36 266030.0 -173000.0 -1.47 -1.2951 -0.855 3069318 PK04_102120 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G01 compound treatment 241040.0 -221000.0 -1.88 221280.0 -218000.0 -1.85 -2.6364 -1.0 3069320 PK04_102121 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO)nn2)/C=C/C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G02 compound treatment 410020.0 -51700.0 -0.44 298830.0 -141000.0 -1.19 -1.1547 -0.9081 3188627 PK04_102122 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G03 mock treatment 349660.0 -112000.0 -0.95 252670.0 -187000.0 -1.58 -1.7947 -0.9705 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G04 mock treatment 503080.0 41300.0 0.35 422210.0 -17300.0 -0.15 0.1452 0.3811 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G05 compound treatment 220330.0 -241000.0 -2.05 370460.0 -69000.0 -0.59 -1.8661 -0.8738 3069321 PK04_102123 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G06 compound treatment 168800.0 -293000.0 -2.49 155240.0 -284000.0 -2.41 -3.4671 -0.9999 3188628 PK04_102124 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G07 compound treatment 211680.0 -250000.0 -2.13 238130.0 -201000.0 -1.71 -2.7119 -0.9941 3069362 PK04_102125 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4ccccc43 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G08 compound treatment 247640.0 -214000.0 -1.82 221940.0 -218000.0 -1.85 -2.5927 -1.0 3188629 PK04_102126 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCOC6=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G09 compound treatment 251620.0 -210000.0 -1.79 169330.0 -270000.0 -2.29 -2.8843 -0.9925 3188630 PK04_102127 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G10 compound treatment 372640.0 -89100.0 -0.76 286310.0 -153000.0 -1.3 -1.4547 -0.9671 3188631 PK04_102128 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G11 compound treatment 222520.0 -239000.0 -2.04 168920.0 -271000.0 -2.29 -3.0619 -0.9982 3069365 PK04_102129 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(C)c4c3cc(C)cc4Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G12 compound treatment 453760.0 -7990.0 -0.07 403100.0 -36400.0 -0.31 -0.2662 -0.8426 3188632 PK04_102130 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G13 compound treatment 278880.0 -183000.0 -1.56 226040.0 -213000.0 -1.81 -2.3802 -0.9971 3069368 PK04_102131 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccccc43 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G14 compound treatment 200340.0 -261000.0 -2.22 148100.0 -291000.0 -2.47 -3.3202 -0.9986 3069370 PK04_102132 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G15 compound treatment 244850.0 -217000.0 -1.85 273760.0 -166000.0 -1.41 -2.2987 -0.991 3188633 PK04_102133 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)/C=C/C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G16 compound treatment 243810.0 -218000.0 -1.85 254800.0 -185000.0 -1.57 -2.4187 -0.9965 3188634 PK04_102134 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G17 compound treatment 133380.0 -328000.0 -2.79 125660.0 -314000.0 -2.66 -3.8576 -0.9997 3188635 PK04_102135 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G18 compound treatment 295400.0 -166000.0 -1.42 422020.0 -17400.0 -0.15 -1.1053 -0.7768 3069408 PK04_102136 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCOC6=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G19 mock treatment 435520.0 -26200.0 -0.22 450120.0 10700.0 0.09 -0.0938 -0.3898 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G20 mock treatment 470130.0 8380.0 0.07 434620.0 -4840.0 -0.04 0.0214 0.2597 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G21 compound treatment 201600.0 -260000.0 -2.21 223200.0 -216000.0 -1.83 -2.8621 -0.9957 3188636 PK04_102137 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G22 compound treatment 258510.0 -203000.0 -1.73 212390.0 -227000.0 -1.93 -2.5846 -0.9985 3188637 PK04_102138 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G23 compound treatment 261390.0 -200000.0 -1.7 387940.0 -51500.0 -0.44 -1.5143 -0.8606 3069412 PK04_102139 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c3c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 G24 compound treatment 255710.0 -206000.0 -1.75 341860.0 -97600.0 -0.83 -1.8249 -0.9414 3188638 PK04_102140 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H01 compound treatment 286210.0 -176000.0 -1.49 225040.0 -214000.0 -1.82 -2.3421 -0.9952 3188639 PK04_102141 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H02 compound treatment 322240.0 -140000.0 -1.19 330530.0 -109000.0 -0.92 -1.4926 -0.9923 3069414 PK04_102142 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H03 mock treatment 430660.0 -31100.0 -0.26 464900.0 25400.0 0.22 -0.0344 -0.1009 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H04 mock treatment 502560.0 40800.0 0.35 451970.0 12500.0 0.11 0.3205 0.8829 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H05 compound treatment 320090.0 -142000.0 -1.21 282900.0 -157000.0 -1.33 -1.7912 -0.9988 3188755 PK04_102143 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H06 compound treatment 333800.0 -128000.0 -1.09 315930.0 -124000.0 -1.05 -1.5106 -0.9998 3188362 PK04_102144 C[C@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H07 compound treatment 366150.0 -95600.0 -0.81 231360.0 -208000.0 -1.77 -1.8233 -0.9381 3188756 PK04_102145 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCCCC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H08 compound treatment 257510.0 -204000.0 -1.74 252270.0 -187000.0 -1.59 -2.3514 -0.999 3069452 PK04_102146 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H09 compound treatment 406140.0 -55600.0 -0.47 307440.0 -132000.0 -1.12 -1.1264 -0.9265 3188757 PK04_102147 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCOC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H10 compound treatment 147750.0 -314000.0 -2.67 125870.0 -314000.0 -2.66 -3.7699 -1.0 3069454 PK04_102148 COc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H11 compound treatment 319130.0 -143000.0 -1.21 181680.0 -258000.0 -2.19 -2.4041 -0.9614 3188758 PK04_102149 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H12 compound treatment 358560.0 -103000.0 -0.88 308000.0 -131000.0 -1.12 -1.4093 -0.993 3069456 PK04_102150 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H13 compound treatment 365450.0 -96300.0 -0.82 378910.0 -60600.0 -0.51 -0.9425 -0.9747 3188759 PK04_102151 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H14 compound treatment 67310.0 -394000.0 -3.36 9050.0 -430000.0 -3.65 -4.9545 -0.9991 3069458 PK04_102152 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H15 compound treatment 348250.0 -113000.0 -0.97 348890.0 -90600.0 -0.77 -1.226 -0.9936 3188760 PK04_102153 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H16 compound treatment 445090.0 -16700.0 -0.14 406400.0 -33100.0 -0.28 -0.2985 -0.95 3069460 PK04_102154 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H17 compound treatment 256480.0 -205000.0 -1.75 267800.0 -172000.0 -1.46 -2.2645 -0.9959 3188761 PK04_102155 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H18 compound treatment 43090.0 -419000.0 -3.56 52890.0 -387000.0 -3.28 -4.8372 -0.9991 3069461 PK04_102156 COc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H19 mock treatment 386650.0 -75100.0 -0.64 449970.0 10500.0 0.09 -0.3887 -0.6026 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H20 mock treatment 400450.0 -61300.0 -0.52 436530.0 -2930.0 -0.02 -0.3863 -0.74 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H21 compound treatment 427080.0 -34700.0 -0.29 267040.0 -172000.0 -1.46 -1.2428 -0.8329 3188762 PK04_102157 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H22 compound treatment 331210.0 -131000.0 -1.11 224410.0 -215000.0 -1.82 -2.0752 -0.9717 3069504 PK04_102158 O[C@H](CC=C)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H23 compound treatment 289030.0 -173000.0 -1.47 258040.0 -181000.0 -1.54 -2.1272 -0.9997 3188763 PK04_102159 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 H24 compound treatment 487960.0 26200.0 0.22 362240.0 -77200.0 -0.66 -0.3055 -0.4415 3069401 PK04_102160 CO[C@H](C=C)[C@H](O)c1ccc(OC)c(O)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I01 compound treatment 376420.0 -85300.0 -0.73 388740.0 -50700.0 -0.43 -0.8175 -0.9688 3069507 PK04_102161 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I02 compound treatment 276040.0 -186000.0 -1.58 198670.0 -241000.0 -2.04 -2.5615 -0.9919 3188764 PK04_102162 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7ccccc7Oc8ccccc68 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I03 compound treatment 342610.0 -119000.0 -1.01 312690.0 -127000.0 -1.08 -1.4771 -0.9996 3188765 PK04_102163 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I04 compound treatment 112160.0 -350000.0 -2.97 55090.0 -384000.0 -3.26 -4.4085 -0.9989 3069594 PK04_102164 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(NC(=O)C)c4)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I05 mock treatment 478500.0 16800.0 0.14 365280.0 -74200.0 -0.63 -0.3442 -0.5334 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I06 mock treatment 535700.0 74000.0 0.63 428550.0 -10900.0 -0.09 0.3794 0.5966 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I07 compound treatment 500450.0 38700.0 0.33 444240.0 4780.0 0.04 0.2615 0.7882 3188766 PK04_102165 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)/C=C/C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I08 compound treatment 387120.0 -74600.0 -0.63 357360.0 -82100.0 -0.7 -0.9414 -0.9989 3188767 PK04_102166 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I09 compound treatment 476970.0 15200.0 0.13 459220.0 19800.0 0.17 0.2101 0.9919 3069598 PK04_102167 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I10 compound treatment 348550.0 -113000.0 -0.96 183170.0 -256000.0 -2.17 -2.2182 -0.9329 3188768 PK04_102168 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I11 compound treatment 292220.0 -170000.0 -1.44 255870.0 -184000.0 -1.56 -2.121 -0.9993 3188769 PK04_102169 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(I)cc43 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I12 compound treatment 167040.0 -295000.0 -2.51 167060.0 -272000.0 -2.31 -3.4068 -0.9992 3069636 PK04_102170 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I13 compound treatment 353400.0 -108000.0 -0.92 262020.0 -177000.0 -1.51 -1.7161 -0.9723 3188770 PK04_102171 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I14 compound treatment 96740.0 -365000.0 -3.11 81490.0 -358000.0 -3.04 -4.3429 -0.9999 3188771 PK04_102172 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I15 compound treatment 412440.0 -49300.0 -0.42 402990.0 -36500.0 -0.31 -0.5154 -0.9888 3069640 PK04_102173 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I16 compound treatment 267780.0 -194000.0 -1.65 191150.0 -248000.0 -2.11 -2.6562 -0.9927 3188888 PK04_102174 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I17 compound treatment 284660.0 -177000.0 -1.51 239550.0 -200000.0 -1.7 -2.2644 -0.9983 3069645 PK04_102175 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I18 compound treatment 484800.0 23100.0 0.2 362830.0 -76600.0 -0.65 -0.321 -0.4727 3188889 PK04_102176 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I19 compound treatment 169410.0 -292000.0 -2.49 148800.0 -291000.0 -2.47 -3.502 -1.0 3069647 PK04_102177 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I20 compound treatment 242270.0 -219000.0 -1.87 236500.0 -203000.0 -1.72 -2.5377 -0.9992 3188890 PK04_102178 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I21 mock treatment 487590.0 25800.0 0.22 497210.0 57700.0 0.49 0.5018 0.9347 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I22 mock treatment 459700.0 -2050.0 -0.02 495800.0 56300.0 0.48 0.3256 0.6809 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I23 compound treatment 363860.0 -97900.0 -0.83 259140.0 -180000.0 -1.53 -1.6705 -0.9591 3188891 PK04_102179 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 I24 compound treatment 289600.0 -172000.0 -1.46 350000.0 -89500.0 -0.76 -1.5722 -0.9532 3069706 PK04_102180 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N(C=O)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J01 compound treatment 267760.0 -194000.0 -1.65 197390.0 -242000.0 -2.05 -2.6189 -0.9941 3188892 PK04_102181 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J02 compound treatment 390430.0 -71300.0 -0.61 374160.0 -65300.0 -0.55 -0.8207 -0.999 3069707 PK04_102182 CSc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J03 compound treatment 185050.0 -277000.0 -2.35 245120.0 -194000.0 -1.65 -2.8302 -0.9848 3188893 PK04_102183 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J04 compound treatment 432900.0 -28800.0 -0.25 401840.0 -37600.0 -0.32 -0.3992 -0.9916 3069711 PK04_102184 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J05 mock treatment 435050.0 -26700.0 -0.23 435680.0 -3780.0 -0.03 -0.1833 -0.7991 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J06 mock treatment 487930.0 26200.0 0.22 377920.0 -61500.0 -0.52 -0.2116 -0.3729 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J07 compound treatment 424900.0 -36800.0 -0.31 354400.0 -85100.0 -0.72 -0.7319 -0.9303 3188894 PK04_102185 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J08 compound treatment 165850.0 -296000.0 -2.52 8860.0 -431000.0 -3.65 -4.3628 -0.9835 3069714 PK04_102186 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J09 compound treatment 354300.0 -107000.0 -0.91 255840.0 -184000.0 -1.56 -1.7478 -0.9677 3188895 PK04_102187 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J10 compound treatment 473080.0 11300.0 0.1 462290.0 22800.0 0.19 0.2051 0.9482 3069716 PK04_102188 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J11 compound treatment 346400.0 -115000.0 -0.98 264830.0 -175000.0 -1.48 -1.7414 -0.98 3188896 PK04_102189 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J12 compound treatment 188860.0 -273000.0 -2.32 100520.0 -339000.0 -2.88 -3.6746 -0.9944 3069744 PK04_102190 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J13 compound treatment 349210.0 -113000.0 -0.96 247380.0 -192000.0 -1.63 -1.8291 -0.9679 3188897 PK04_102191 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J14 compound treatment 483240.0 21500.0 0.18 448540.0 9080.0 0.08 0.1837 0.9261 3069746 PK04_102192 OCCOc1ccc(cc1)[C@@H](O)CC=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J15 compound treatment 342240.0 -120000.0 -1.02 291440.0 -148000.0 -1.26 -1.6068 -0.9945 3069749 PK04_102193 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J16 compound treatment 446620.0 -15100.0 -0.13 396570.0 -42900.0 -0.36 -0.3483 -0.9024 3188898 PK04_102194 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J17 compound treatment 361400.0 -100000.0 -0.85 327900.0 -112000.0 -0.95 -1.2728 -0.9987 3188899 PK04_102195 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N5CCC[C@H]5CO)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J18 compound treatment 257990.0 -204000.0 -1.73 266030.0 -173000.0 -1.47 -2.266 -0.9967 3069504 PK04_102196 O[C@H](CC=C)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J19 compound treatment 447110.0 -14600.0 -0.12 433200.0 -6260.0 -0.05 -0.1256 -0.9279 3188900 PK04_102197 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J20 compound treatment 286960.0 -175000.0 -1.49 215520.0 -224000.0 -1.9 -2.3947 -0.9927 3069264 PK04_102198 C[C@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J21 mock treatment 439550.0 -22200.0 -0.19 402030.0 -37400.0 -0.32 -0.3581 -0.9692 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J22 mock treatment 442910.0 -18800.0 -0.16 486970.0 47500.0 0.4 0.1716 0.3958 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J23 compound treatment 281540.0 -180000.0 -1.53 303630.0 -136000.0 -1.15 -1.8988 -0.9901 3069786 PK04_102199 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 J24 compound treatment 428010.0 -33700.0 -0.29 419960.0 -19500.0 -0.17 -0.3199 -0.9658 3188901 PK04_102200 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K01 compound treatment 367800.0 -93900.0 -0.8 376240.0 -63200.0 -0.54 -0.9444 -0.9812 3069787 PK04_102201 COc1ccc(cc1)[Si](C)(C)[C@@H](CCn2cc(CCO)nn2)/C=C/C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K02 compound treatment 170430.0 -291000.0 -2.48 239590.0 -200000.0 -1.7 -2.9513 -0.9829 3188902 PK04_102202 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K03 compound treatment 427310.0 -34400.0 -0.29 448000.0 8540.0 0.07 -0.1559 -0.5168 3188903 PK04_102203 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K04 compound treatment 244960.0 -217000.0 -1.84 157280.0 -282000.0 -2.39 -2.9967 -0.9917 3069790 PK04_102204 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K05 compound treatment 490010.0 28300.0 0.24 339410.0 -100000.0 -0.85 -0.4301 -0.4876 3188904 PK04_102205 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K06 compound treatment 183680.0 -278000.0 -2.37 57520.0 -382000.0 -3.24 -3.9637 -0.9881 3189012 PK04_102206 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K07 mock treatment 535110.0 73400.0 0.62 376190.0 -63300.0 -0.54 0.0618 0.0751 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K08 mock treatment 503490.0 41700.0 0.36 413120.0 -26300.0 -0.22 0.0931 0.2219 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K09 compound treatment 388850.0 -72900.0 -0.62 437190.0 -2270.0 -0.02 -0.4521 -0.7288 3069821 PK04_102207 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K10 compound treatment 379200.0 -82500.0 -0.7 340960.0 -98500.0 -0.84 -1.0874 -0.9963 3189013 PK04_102208 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)C)cc43 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K11 compound treatment 270370.0 -191000.0 -1.63 246280.0 -193000.0 -1.64 -2.31 -1.0 3069825 PK04_102209 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K12 compound treatment 358970.0 -103000.0 -0.87 311200.0 -128000.0 -1.09 -1.3876 -0.9941 3189014 PK04_102210 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K13 compound treatment 489720.0 28000.0 0.24 493680.0 54200.0 0.46 0.4935 0.953 3189015 PK04_102211 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5c3cc(C)cc5Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K14 compound treatment 191130.0 -271000.0 -2.3 190830.0 -249000.0 -2.11 -3.1193 -0.999 3069831 PK04_102212 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCOC5=O)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K15 mock treatment 503170.0 41400.0 0.35 463730.0 24300.0 0.21 0.3947 0.9672 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K16 mock treatment 504100.0 42400.0 0.36 472010.0 32500.0 0.28 0.45 0.9914 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K17 compound treatment 355780.0 -106000.0 -0.9 259850.0 -180000.0 -1.52 -1.7148 -0.9686 3189016 PK04_102213 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)COc6ccccc56 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K18 compound treatment 247840.0 -214000.0 -1.82 256400.0 -183000.0 -1.55 -2.3848 -0.9969 3069867 PK04_102214 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K19 compound treatment 267320.0 -194000.0 -1.65 252710.0 -187000.0 -1.58 -2.2898 -0.9998 3189017 PK04_102215 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K20 compound treatment 264360.0 -197000.0 -1.68 248640.0 -191000.0 -1.62 -2.332 -0.9998 3069873 PK04_102216 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c3c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K21 compound treatment 257320.0 -204000.0 -1.74 234880.0 -205000.0 -1.74 -2.4569 -1.0 3189018 PK04_102217 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5C(=O)c6cccc7cccc5c67)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K22 compound treatment 318240.0 -144000.0 -1.22 339240.0 -100000.0 -0.85 -1.4644 -0.9844 3189019 PK04_102218 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(CCO)nn5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K23 mock treatment 491390.0 29600.0 0.25 482040.0 42600.0 0.36 0.4337 0.9846 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 K24 mock treatment 479580.0 17800.0 0.15 434370.0 -5090.0 -0.04 0.0767 0.4864 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L01 compound treatment 377000.0 -84700.0 -0.72 358400.0 -81100.0 -0.69 -0.996 -0.9997 3069879 PK04_102219 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L02 compound treatment 400870.0 -60900.0 -0.52 233240.0 -206000.0 -1.75 -1.6032 -0.8787 3189020 PK04_102220 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L03 compound treatment 256720.0 -205000.0 -1.74 341480.0 -98000.0 -0.83 -1.8211 -0.9425 3189021 PK04_102221 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L04 compound treatment 379900.0 -81800.0 -0.7 484110.0 44600.0 0.38 -0.2246 -0.2833 3069907 PK04_102222 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L05 compound treatment 261440.0 -200000.0 -1.7 267170.0 -172000.0 -1.46 -2.2384 -0.9971 3189022 PK04_102223 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L06 compound treatment 351390.0 -110000.0 -0.94 344480.0 -95000.0 -0.81 -1.2336 -0.9971 3069909 PK04_102224 C[C@@H](C=C)[C@@H](O)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L07 mock treatment 491750.0 30000.0 0.26 490120.0 50700.0 0.43 0.4843 0.9691 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L08 mock treatment 486300.0 24600.0 0.21 480640.0 41200.0 0.35 0.3947 0.9698 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L09 compound treatment 255370.0 -206000.0 -1.76 236280.0 -203000.0 -1.72 -2.4602 -1.0 3189023 PK04_102225 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L10 compound treatment 423050.0 -38700.0 -0.33 435360.0 -4100.0 -0.03 -0.2574 -0.7776 3069912 PK04_102226 COc1ccc(NC(=O)O[C@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L11 compound treatment 414270.0 -47500.0 -0.4 414170.0 -25300.0 -0.21 -0.4373 -0.9562 3189024 PK04_102227 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L12 compound treatment 501890.0 40100.0 0.34 424320.0 -15100.0 -0.13 0.1507 0.4129 3069746 PK04_102228 OCCOc1ccc(cc1)[C@@H](O)CC=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L13 compound treatment 387370.0 -74400.0 -0.63 256590.0 -183000.0 -1.55 -1.5443 -0.9218 3069917 PK04_102229 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCC5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L14 compound treatment 428190.0 -33600.0 -0.29 322240.0 -117000.0 -0.99 -0.905 -0.8748 3069920 PK04_102230 O[C@@H](CC=C)c1ccc(O)c(F)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L15 mock treatment 458940.0 -2810.0 -0.02 498720.0 59300.0 0.5 0.3386 0.6728 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L16 mock treatment 500000.0 38300.0 0.33 485010.0 45500.0 0.39 0.5033 0.9964 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L17 compound treatment 480730.0 19000.0 0.16 456860.0 17400.0 0.15 0.2185 0.999 3189025 PK04_102231 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCOC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L18 compound treatment 474420.0 12700.0 0.11 502560.0 63100.0 0.54 0.4547 0.8328 3069953 PK04_102232 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L19 compound treatment 245280.0 -216000.0 -1.84 175210.0 -264000.0 -2.24 -2.8872 -0.9952 3189026 PK04_102233 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L20 compound treatment 412990.0 -48800.0 -0.41 493280.0 53800.0 0.46 0.0295 0.0478 3069956 PK04_102234 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L21 compound treatment 465440.0 3690.0 0.03 424430.0 -15000.0 -0.13 -0.068 -0.5173 3189027 PK04_102235 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L22 compound treatment 470630.0 8880.0 0.08 440540.0 1080.0 0.01 0.0599 0.7868 3069961 PK04_102236 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L23 mock treatment 420320.0 -41400.0 -0.35 473600.0 34100.0 0.29 -0.0444 -0.0974 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 L24 mock treatment 465670.0 3920.0 0.03 451390.0 11900.0 0.1 0.0951 0.8931 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M01 compound treatment 303870.0 -158000.0 -1.34 323050.0 -116000.0 -0.99 -1.648 -0.9886 3069962 PK04_102237 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(c5ccccc53)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M02 compound treatment 176370.0 -285000.0 -2.43 172360.0 -267000.0 -2.27 -3.3188 -0.9994 3188628 PK04_102238 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M03 compound treatment 409930.0 -51800.0 -0.44 262990.0 -176000.0 -1.5 -1.3702 -0.878 3189028 PK04_102239 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6c3cc(C)cc6Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M04 compound treatment 393920.0 -67800.0 -0.58 324040.0 -115000.0 -0.98 -1.1003 -0.9682 3189141 PK04_102240 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCCCC5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M05 compound treatment 314560.0 -147000.0 -1.25 198110.0 -241000.0 -2.05 -2.3331 -0.9722 3069277 PK04_102241 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M06 compound treatment 263010.0 -199000.0 -1.69 217840.0 -222000.0 -1.88 -2.5248 -0.9986 3189142 PK04_102242 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(CCO)nn5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M07 compound treatment 390250.0 -71500.0 -0.61 245150.0 -194000.0 -1.65 -1.5956 -0.9082 3189143 PK04_102243 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N4c5c3cc(OC)cc5C(=CC4(C)C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M08 compound treatment 217970.0 -244000.0 -2.07 215520.0 -224000.0 -1.9 -2.8097 -0.999 3069284 PK04_102244 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)[C@H](C)O)cc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M09 mock treatment 502650.0 40900.0 0.35 471130.0 31700.0 0.27 0.436 0.9918 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M10 mock treatment 510300.0 48600.0 0.41 508960.0 69500.0 0.59 0.7089 0.9849 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M11 compound treatment 429200.0 -32500.0 -0.28 460520.0 21100.0 0.18 -0.0695 -0.2109 3189144 PK04_102245 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(C)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M12 compound treatment 469210.0 7460.0 0.06 362130.0 -77300.0 -0.66 -0.419 -0.6357 3189145 PK04_102246 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M13 mock treatment 508030.0 46300.0 0.39 437320.0 -2140.0 -0.02 0.2656 0.6737 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M14 mock treatment 482030.0 20300.0 0.17 483100.0 43600.0 0.37 0.3838 0.9397 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M15 compound treatment 449940.0 -11800.0 -0.1 342850.0 -96600.0 -0.82 -0.6505 -0.7879 3189146 PK04_102247 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M16 compound treatment 438190.0 -23600.0 -0.2 357070.0 -82400.0 -0.7 -0.6359 -0.8746 3189147 PK04_102248 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M17 compound treatment 142290.0 -319000.0 -2.72 150580.0 -289000.0 -2.45 -3.6545 -0.9987 3069327 PK04_102249 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M18 compound treatment 394880.0 -66900.0 -0.57 282080.0 -157000.0 -1.34 -1.3463 -0.9277 3189148 PK04_102250 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5CCOC5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M19 compound treatment 437210.0 -24500.0 -0.21 437380.0 -2080.0 -0.02 -0.1601 -0.7643 3069330 PK04_102251 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M20 compound treatment 360100.0 -102000.0 -0.86 325500.0 -114000.0 -0.97 -1.295 -0.9985 3189149 PK04_102252 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCCCC5=O)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M21 compound treatment 176350.0 -285000.0 -2.43 174340.0 -265000.0 -2.25 -3.3071 -0.9993 3189150 PK04_102253 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)c6ccccc6Oc7ccccc57)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M22 compound treatment 366300.0 -95400.0 -0.81 431290.0 -8170.0 -0.07 -0.6232 -0.7647 3189151 PK04_102254 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCOC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M23 compound treatment 241660.0 -220000.0 -1.87 350720.0 -88700.0 -0.75 -1.8562 -0.9198 3189152 PK04_102255 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 M24 compound treatment 248130.0 -214000.0 -1.82 281310.0 -158000.0 -1.34 -2.2337 -0.9888 3069375 PK04_102256 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)c5ccc(OC)cc5)c6ccccc36)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N01 compound treatment 264700.0 -197000.0 -1.68 380800.0 -58700.0 -0.5 -1.5372 -0.8791 3189153 PK04_102257 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N02 compound treatment 434670.0 -27100.0 -0.23 380500.0 -59000.0 -0.5 -0.5166 -0.938 3069379 PK04_102258 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N03 compound treatment 354480.0 -107000.0 -0.91 409390.0 -30100.0 -0.26 -0.8257 -0.8714 3189154 PK04_102259 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6ccc(cc6)N7CCC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N04 compound treatment 507300.0 45600.0 0.39 247280.0 -192000.0 -1.63 -0.8787 -0.5244 3069716 PK04_102260 CO[C@@H](C=C)[C@@H](O)c1ccc(O)c(F)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N05 compound treatment 434600.0 -27100.0 -0.23 293600.0 -146000.0 -1.24 -1.0382 -0.8248 3069403 PK04_102261 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6CCC6=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N06 compound treatment 445860.0 -15900.0 -0.14 354280.0 -85200.0 -0.72 -0.6065 -0.825 3069417 PK04_102262 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N07 compound treatment 431730.0 -30000.0 -0.26 350660.0 -88800.0 -0.75 -0.7132 -0.8967 3189155 PK04_102263 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CC(=O)N(CCO)Cc5ccccc5)[C@H]([C@@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N08 compound treatment 450890.0 -10900.0 -0.09 484330.0 44900.0 0.38 0.2038 0.5204 3069421 PK04_102264 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N09 mock treatment 482930.0 21200.0 0.18 448880.0 9420.0 0.08 0.1839 0.933 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N10 mock treatment 478030.0 16300.0 0.14 496280.0 56800.0 0.48 0.4388 0.8749 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N11 compound treatment 365970.0 -95800.0 -0.81 360000.0 -79500.0 -0.67 -1.0528 -0.9956 3189156 PK04_102265 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5Cc6ccccc6C[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c7ccc(OC)cc7)c8ccccc38)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N12 compound treatment 311800.0 -150000.0 -1.28 333390.0 -106000.0 -0.9 -1.5383 -0.9854 3069424 PK04_102266 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N13 mock treatment 480960.0 19200.0 0.16 442520.0 3060.0 0.03 0.1339 0.8091 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N14 mock treatment 462650.0 905.0 0.01 476570.0 37100.0 0.31 0.228 0.7242 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N15 compound treatment 414890.0 -46900.0 -0.4 449020.0 9560.0 0.08 -0.2245 -0.552 3189268 PK04_102267 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)c8cccc9cccc7c89)c%10ccccc%103 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N16 compound treatment 447220.0 -14500.0 -0.12 430400.0 -9060.0 -0.08 -0.1417 -0.9739 3069404 PK04_102268 C[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N17 compound treatment 457340.0 -4410.0 -0.04 504870.0 65400.0 0.55 0.3658 0.6578 3069428 PK04_102269 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6CCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N18 compound treatment 436370.0 -25400.0 -0.22 456640.0 17200.0 0.15 -0.0496 -0.1905 3189269 PK04_102270 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N19 compound treatment 407370.0 -54400.0 -0.46 428700.0 -10800.0 -0.09 -0.3917 -0.8307 3070277 PK04_102271 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N5CCC[C@H]5CO)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N20 compound treatment 455640.0 -6110.0 -0.05 470770.0 31300.0 0.27 0.1511 0.5582 3069270 PK04_102272 CO[C@@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N21 compound treatment 282770.0 -179000.0 -1.52 289650.0 -150000.0 -1.27 -1.9753 -0.996 3070278 PK04_102273 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5CCC5=O)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N22 compound treatment 240890.0 -221000.0 -1.88 292290.0 -147000.0 -1.25 -2.2113 -0.9803 3070279 PK04_102274 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N23 compound treatment 403910.0 -57800.0 -0.49 431910.0 -7550.0 -0.06 -0.3932 -0.7925 3070280 PK04_102275 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 N24 compound treatment 447420.0 -14300.0 -0.12 467840.0 28400.0 0.24 0.084 0.3115 3189270 PK04_102276 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O01 compound treatment 403310.0 -58400.0 -0.5 396860.0 -42600.0 -0.36 -0.6071 -0.9877 3189271 PK04_102277 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(c5ccccc53)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O02 compound treatment 189070.0 -273000.0 -2.32 174460.0 -265000.0 -2.25 -3.2298 -0.9999 3070281 PK04_102278 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N(C=O)c5ccccc5)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O03 compound treatment 364870.0 -96900.0 -0.82 375550.0 -63900.0 -0.54 -0.9661 -0.9794 3189272 PK04_102279 COc1ccc(cc1)[Si](C)(C)[C@@H](CC(=O)N2CCC[C@H]2CO)/C=C/C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O04 compound treatment 290910.0 -171000.0 -1.45 209920.0 -230000.0 -1.95 -2.4045 -0.9896 3189273 PK04_102280 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(NC(=O)[C@H](C)O)c4)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O05 compound treatment 168640.0 -293000.0 -2.49 160770.0 -279000.0 -2.36 -3.4349 -0.9996 3070282 PK04_102281 COc1ccc(cc1)[Si](C)(C)[C@H](CC(=O)N(CCO)Cc2ccccc2)/C=C/C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O06 compound treatment 120340.0 -341000.0 -2.9 111230.0 -328000.0 -2.78 -4.0226 -0.9998 3189274 PK04_102282 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6cccc7cccc5c67 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O07 compound treatment 286030.0 -176000.0 -1.49 271260.0 -168000.0 -1.43 -2.0659 -0.9997 3070283 PK04_102283 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O08 compound treatment 215200.0 -247000.0 -2.1 169070.0 -270000.0 -2.29 -3.105 -0.999 3189275 PK04_102284 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N(C=O)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O09 compound treatment 329220.0 -133000.0 -1.13 348840.0 -90600.0 -0.77 -1.3408 -0.9826 3189276 PK04_102285 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(C)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O10 compound treatment 224380.0 -237000.0 -2.02 244670.0 -195000.0 -1.65 -2.5963 -0.995 3070284 PK04_102286 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O11 mock treatment 480360.0 18600.0 0.16 356820.0 -82600.0 -0.7 -0.3837 -0.5339 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O12 mock treatment 474300.0 12600.0 0.11 428710.0 -10800.0 -0.09 0.011 0.0784 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O13 compound treatment 329000.0 -133000.0 -1.13 345530.0 -93900.0 -0.8 -1.362 -0.9854 3189277 PK04_102287 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(C)c4ccccc43 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O14 compound treatment 313170.0 -149000.0 -1.26 391200.0 -48300.0 -0.41 -1.1833 -0.8906 3189278 PK04_102288 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(NC(=O)[C@H](C)O)cc43 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O15 compound treatment 299610.0 -162000.0 -1.38 253480.0 -186000.0 -1.58 -2.0909 -0.9978 3070285 PK04_102289 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(c4ccccc43)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O16 compound treatment 334610.0 -127000.0 -1.08 249410.0 -190000.0 -1.61 -1.9048 -0.9811 3189279 PK04_102290 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@]4(O[C@H](CCn5cc(nn5)[C@H](O)c6ccccc6)[C@H]([C@@H]4C)[Si](C)(C)c7ccc(OC)cc7)c3c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O17 compound treatment 442560.0 -19200.0 -0.16 406650.0 -32800.0 -0.28 -0.3122 -0.9676 3070286 PK04_102291 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(CC=C)c6ccc(cc63)N7C(=O)c8cccc9cccc7c89 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O18 compound treatment 313370.0 -148000.0 -1.26 313470.0 -126000.0 -1.07 -1.6483 -0.9966 3189280 PK04_102292 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCCCC6=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O19 compound treatment 222740.0 -239000.0 -2.03 305550.0 -134000.0 -1.14 -2.241 -0.9622 3189281 PK04_102293 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O20 compound treatment 178450.0 -283000.0 -2.41 197170.0 -242000.0 -2.06 -3.1575 -0.9969 3070287 PK04_102294 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccc(cc4)N5CCCCC5=O)c6ccccc63 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O21 compound treatment 231620.0 -230000.0 -1.96 254040.0 -185000.0 -1.57 -2.4965 -0.9941 3189282 PK04_102295 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4cccc(c4)N5C(=O)COc6ccccc56)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O22 compound treatment 360370.0 -101000.0 -0.86 284970.0 -154000.0 -1.31 -1.5365 -0.9794 3070288 PK04_102296 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(CC=C)c4ccc(cc43)N5C(=O)c6ccccc6Oc7ccccc57 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O23 compound treatment 299420.0 -162000.0 -1.38 245040.0 -194000.0 -1.65 -2.1427 -0.9961 3189283 PK04_102297 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(CC=C)c5ccc(cc53)N6C(=O)c7cccc8cccc6c78 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 O24 compound treatment 240910.0 -221000.0 -1.88 190560.0 -249000.0 -2.11 -2.8214 -0.9983 3189284 PK04_102298 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCO)C(=O)N(Cc4ccc(NC(=O)C)cc4)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P01 compound treatment 163520.0 -298000.0 -2.54 176930.0 -263000.0 -2.23 -3.3687 -0.9979 3070289 PK04_102299 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(CCO)nn4)C(=O)N(Cc5ccc(cc5)N6CCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P02 compound treatment 349940.0 -112000.0 -0.95 306600.0 -133000.0 -1.13 -1.4695 -0.9964 3069953 PK04_102300 CO[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P03 compound treatment 209410.0 -252000.0 -2.15 154300.0 -285000.0 -2.42 -3.2284 -0.9982 3189285 PK04_102301 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4Cc5ccccc5C[C@H]4CO)C(=O)N(Cc6cccc(c6)N7C(=O)COc8ccccc78)c9ccccc93 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P04 compound treatment 176570.0 -285000.0 -2.43 168120.0 -271000.0 -2.3 -3.3431 -0.9997 3070290 PK04_102302 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P05 compound treatment 288010.0 -174000.0 -1.48 111810.0 -328000.0 -2.78 -3.0104 -0.9563 3189394 PK04_102303 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(CCO)nn4)C(=O)N(C)c5c3cc(C)cc5Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P06 compound treatment 273600.0 -188000.0 -1.6 325530.0 -114000.0 -0.97 -1.8152 -0.9708 3069907 PK04_102304 C[C@H](C=C)[C@@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P07 compound treatment 351480.0 -110000.0 -0.94 334780.0 -105000.0 -0.89 -1.2912 -0.9996 3189395 PK04_102305 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(Cc6cccc(c6)N7CCC7=O)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P08 compound treatment 354590.0 -107000.0 -0.91 324800.0 -115000.0 -0.97 -1.3324 -0.9995 3069314 PK04_102306 CO[C@H](C=C)[C@H](O)c1ccc(O)c(F)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P09 compound treatment 299710.0 -162000.0 -1.38 202030.0 -237000.0 -2.01 -2.3989 -0.9829 3070291 PK04_102307 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6CCCCC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P10 compound treatment 282280.0 -179000.0 -1.53 253780.0 -186000.0 -1.58 -2.1934 -0.9999 3189396 PK04_102308 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P11 mock treatment 305350.0 -156000.0 -1.33 349570.0 -89900.0 -0.76 -1.48 -0.9651 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P12 mock treatment 369640.0 -92100.0 -0.78 237760.0 -202000.0 -1.71 -1.7639 -0.9373 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P13 compound treatment 276340.0 -185000.0 -1.58 200870.0 -239000.0 -2.02 -2.5465 -0.9924 3189397 PK04_102309 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N(CCO)Cc4ccccc4)C(=O)N(Cc5cccc(c5)N6C(=O)c7cccc8cccc6c78)c9ccccc93 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P14 compound treatment 274130.0 -188000.0 -1.6 269480.0 -170000.0 -1.44 -2.1482 -0.9987 3070292 PK04_102310 OCCOc1ccc(cc1)[C@H](O)CC=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P15 compound treatment 270740.0 -191000.0 -1.62 263060.0 -176000.0 -1.5 -2.2071 -0.9992 3070293 PK04_102311 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@@]4(O[C@@H](CC(=O)N(CCO)Cc5ccccc5)[C@@H]([C@H]4C)[Si](C)(C)c6ccc(OC)cc6)c7ccccc37)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P16 compound treatment 261440.0 -200000.0 -1.7 260030.0 -179000.0 -1.52 -2.2812 -0.9984 3070292 PK04_102312 OCCOc1ccc(cc1)[C@H](O)CC=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P17 compound treatment 295480.0 -166000.0 -1.41 217080.0 -222000.0 -1.89 -2.3341 -0.9899 3189398 PK04_102313 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5ccc(cc5)N6CCOC6=O)c7ccccc73 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P18 compound treatment 232640.0 -229000.0 -1.95 229180.0 -210000.0 -1.78 -2.6395 -0.999 3070294 PK04_102314 CO[C@@H](C=C)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P19 compound treatment 215720.0 -246000.0 -2.09 211060.0 -228000.0 -1.94 -2.85 -0.9993 3189399 PK04_102315 COc1ccc(cc1)[Si](C)(C)[C@@H]2[C@@H](C)[C@@]3(O[C@H]2CC(=O)N4CCC[C@H]4CO)C(=O)N(Cc5cccc(c5)N6C(=O)COc7ccccc67)c8ccccc83 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P20 compound treatment 168040.0 -294000.0 -2.5 194640.0 -245000.0 -2.08 -3.2353 -0.9958 3070290 PK04_102316 C[C@@H](C=C)[C@H](O)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P21 compound treatment 161240.0 -301000.0 -2.56 101240.0 -338000.0 -2.87 -3.8364 -0.9983 3189400 PK04_102317 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccc(cc53)N6CCC6=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P22 compound treatment 240390.0 -221000.0 -1.88 284580.0 -155000.0 -1.31 -2.2606 -0.9845 3070295 PK04_102318 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P23 compound treatment 244650.0 -217000.0 -1.85 185780.0 -254000.0 -2.15 -2.8276 -0.9971 3189401 PK04_102319 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCn4cc(nn4)[C@H](O)c5ccccc5)C(=O)N(C)c6c3cc(C)cc6Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2102 P24 compound treatment 234280.0 -227000.0 -1.94 205560.0 -234000.0 -1.98 -2.7713 -0.9999 3414053 PK04_102320 OCCCOc1ccc(cc1)C2=N[C@](Cc3ccccc3)([C@H](O2)c4ccccc4)C(=O)NO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A01 compound treatment 334790.0 -95400.0 -0.81 230980.0 -170000.0 -1.44 -1.5909 -0.9634 3221174 PK04_130001 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N[C@@H]3[C@H](O)Cc4ccccc34 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A02 compound treatment 372320.0 -57900.0 -0.49 424480.0 24000.0 0.2 -0.2045 -0.3839 3211805 PK04_130002 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A03 compound treatment 427080.0 -3130.0 -0.03 418440.0 17900.0 0.15 0.0887 0.5746 3221177 PK04_130003 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccccc4F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A04 compound treatment 466080.0 35900.0 0.31 452960.0 52400.0 0.44 0.5303 0.9831 3080218 PK04_130004 OCCC[C@@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A05 compound treatment 433650.0 3440.0 0.03 423710.0 23200.0 0.2 0.1598 0.8036 3221180 PK04_130005 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A06 compound treatment 201680.0 -229000.0 -1.94 291000.0 -110000.0 -0.93 -2.0317 -0.9429 3211801 PK04_130006 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A07 compound treatment 397330.0 -32900.0 -0.28 417300.0 16800.0 0.14 -0.0971 -0.3095 3221183 PK04_130007 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A08 compound treatment 214750.0 -215000.0 -1.83 286960.0 -114000.0 -0.96 -1.9773 -0.9549 3080220 PK04_130008 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A09 compound treatment 207380.0 -223000.0 -1.9 200120.0 -200000.0 -1.7 -2.5425 -0.9985 3221185 PK04_130009 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccc(O)cc2)c3coc4ccccc4c3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A10 compound treatment 339360.0 -90800.0 -0.77 405460.0 4940.0 0.04 -0.5169 -0.6678 3080222 PK04_130010 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A11 compound treatment 207040.0 -223000.0 -1.9 279850.0 -121000.0 -1.02 -2.0663 -0.958 3221188 PK04_130011 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3coc4ccccc4c3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A12 compound treatment 339750.0 -90500.0 -0.77 431840.0 31300.0 0.27 -0.3563 -0.4377 3211814 PK04_130012 C[C@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A13 mock treatment 309840.0 -120000.0 -1.02 477180.0 76700.0 0.65 -0.2643 -0.2179 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A14 mock treatment 472500.0 42300.0 0.36 436330.0 35800.0 0.3 0.4692 0.9964 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A15 compound treatment 302160.0 -128000.0 -1.09 253820.0 -147000.0 -1.24 -1.6502 -0.9978 3221191 PK04_130013 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A16 compound treatment 327580.0 -103000.0 -0.87 261600.0 -139000.0 -1.18 -1.4506 -0.9891 3080206 PK04_130014 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A17 compound treatment 393710.0 -36500.0 -0.31 470960.0 70400.0 0.6 0.2029 0.3014 3221194 PK04_130015 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N[C@@H]4[C@H](O)Cc5ccccc45 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A18 compound treatment 360320.0 -69900.0 -0.59 391570.0 -8950.0 -0.08 -0.4741 -0.791 3211690 PK04_130016 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A19 compound treatment 202260.0 -228000.0 -1.94 197130.0 -203000.0 -1.73 -2.5912 -0.9983 3221197 PK04_130017 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3coc4ccccc4c3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A20 compound treatment 314530.0 -116000.0 -0.98 281380.0 -119000.0 -1.01 -1.4105 -0.9999 3189020 PK04_130018 C[C@@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A21 compound treatment 268810.0 -161000.0 -1.37 209970.0 -191000.0 -1.62 -2.1139 -0.9967 2019329 PK04_130019 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCCCCCC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A22 compound treatment 395680.0 -34500.0 -0.29 449700.0 49200.0 0.42 0.0873 0.1711 3080190 PK04_130020 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A23 compound treatment 355870.0 -74300.0 -0.63 393810.0 -6710.0 -0.06 -0.4874 -0.7677 3221200 PK04_130021 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 A24 compound treatment 373280.0 -56900.0 -0.48 287390.0 -113000.0 -0.96 -1.021 -0.9498 3211695 PK04_130022 CO[C@@H](CCO)[C@@H](O)c1ccc(O)c(F)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B01 compound treatment 419240.0 -11000.0 -0.09 455040.0 54500.0 0.46 0.261 0.5533 3176327 PK04_130023 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B02 compound treatment 449310.0 19100.0 0.16 481540.0 81000.0 0.69 0.6009 0.8509 3221203 PK04_130024 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B03 compound treatment 483590.0 53400.0 0.45 467290.0 66800.0 0.57 0.7216 0.994 3052745 PK04_130025 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B04 compound treatment 469770.0 39600.0 0.34 420490.0 20000.0 0.17 0.3578 0.9495 3221205 PK04_130026 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B05 compound treatment 447300.0 17100.0 0.15 418560.0 18000.0 0.15 0.211 0.9997 3176512 PK04_130027 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B06 compound treatment 440440.0 10200.0 0.09 392110.0 -8410.0 -0.07 0.0111 0.0986 3221207 PK04_130028 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B07 compound treatment 427840.0 -2370.0 -0.02 297020.0 -104000.0 -0.88 -0.6351 -0.7231 3176123 PK04_130029 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B08 compound treatment 471600.0 41400.0 0.35 384800.0 -15700.0 -0.13 0.1547 0.4108 3221209 PK04_130030 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B09 compound treatment 429010.0 -1200.0 -0.01 456640.0 56100.0 0.48 0.3294 0.6918 3052645 PK04_130031 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B10 compound treatment 415840.0 -14400.0 -0.12 403860.0 3340.0 0.03 -0.0664 -0.5293 3221211 PK04_130032 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B11 compound treatment 470150.0 39900.0 0.34 393050.0 -7470.0 -0.06 0.1955 0.5654 3052831 PK04_130033 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B12 compound treatment 423760.0 -6450.0 -0.05 266490.0 -134000.0 -1.14 -0.8427 -0.7404 3221213 PK04_130034 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B13 mock treatment 465040.0 34800.0 0.3 391240.0 -9280.0 -0.08 0.1539 0.5018 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B14 mock treatment 513150.0 82900.0 0.71 372130.0 -28400.0 -0.24 0.3286 0.4408 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B15 compound treatment 510620.0 80400.0 0.68 363570.0 -37000.0 -0.31 0.2621 0.3483 3176778 PK04_130035 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B16 compound treatment 465680.0 35500.0 0.3 383550.0 -17000.0 -0.14 0.1116 0.3337 3221214 PK04_130036 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B17 compound treatment 398150.0 -32100.0 -0.27 265570.0 -135000.0 -1.14 -1.0023 -0.8517 3176195 PK04_130037 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B18 compound treatment 347700.0 -82500.0 -0.7 467730.0 67200.0 0.57 -0.0932 -0.1031 3221216 PK04_130038 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B19 compound treatment 400770.0 -29400.0 -0.25 458840.0 58300.0 0.49 0.1727 0.3115 3052584 PK04_130039 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B20 compound treatment 296880.0 -133000.0 -1.13 325150.0 -75400.0 -0.64 -1.2541 -0.9632 3221218 PK04_130040 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B21 compound treatment 363540.0 -66700.0 -0.57 433880.0 33400.0 0.28 -0.201 -0.3171 3176736 PK04_130041 CN(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B22 compound treatment 349440.0 -80800.0 -0.69 363540.0 -37000.0 -0.31 -0.7077 -0.9369 3221220 PK04_130042 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B23 compound treatment 451410.0 21200.0 0.18 386590.0 -13900.0 -0.12 0.044 0.2039 3052927 PK04_130043 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 B24 compound treatment 246350.0 -184000.0 -1.56 420910.0 20400.0 0.17 -0.9837 -0.6251 3221222 PK04_130044 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C01 compound treatment 421600.0 -8610.0 -0.07 355940.0 -44600.0 -0.38 -0.3192 -0.8286 3221224 PK04_130045 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccc(Cl)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C02 compound treatment 432870.0 2660.0 0.02 379490.0 -21000.0 -0.18 -0.1101 -0.6124 3211914 PK04_130046 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C03 compound treatment 374010.0 -56200.0 -0.48 422050.0 21500.0 0.18 -0.2089 -0.4083 3221227 PK04_130047 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C04 compound treatment 429470.0 -736.0 -0.01 379120.0 -21400.0 -0.18 -0.1328 -0.7311 3211809 PK04_130048 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C05 compound treatment 445440.0 15200.0 0.13 339330.0 -61200.0 -0.52 -0.2754 -0.5148 2019446 PK04_130049 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2coc3ccccc3c2=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C06 compound treatment 369220.0 -61000.0 -0.52 378830.0 -21700.0 -0.18 -0.497 -0.9028 3069417 PK04_130050 C[C@H](C=C)[C@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C07 compound treatment 392640.0 -37600.0 -0.32 388840.0 -11700.0 -0.1 -0.2961 -0.8848 3221230 PK04_130051 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccc(O)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C08 compound treatment 401470.0 -28700.0 -0.24 381230.0 -19300.0 -0.16 -0.2886 -0.981 3080227 PK04_130052 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C09 compound treatment 388640.0 -41600.0 -0.35 370240.0 -30300.0 -0.26 -0.4317 -0.9877 3221232 PK04_130053 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C10 compound treatment 404040.0 -26200.0 -0.22 319890.0 -80600.0 -0.68 -0.6411 -0.8912 3080226 PK04_130054 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C11 mock treatment 438880.0 8670.0 0.07 380190.0 -20300.0 -0.17 -0.0698 -0.372 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C12 mock treatment 341510.0 -88700.0 -0.75 381310.0 -19200.0 -0.16 -0.6488 -0.8405 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C13 compound treatment 312100.0 -118000.0 -1.0 399970.0 -553.0 0.0 -0.7138 -0.7104 3221235 PK04_130055 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCCCCCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C14 compound treatment 307360.0 -123000.0 -1.05 247580.0 -153000.0 -1.3 -1.6564 -0.9943 3080272 PK04_130056 OCCC[C@H](O)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C15 mock treatment 395170.0 -35000.0 -0.3 325710.0 -74800.0 -0.63 -0.6595 -0.9406 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C16 mock treatment 397880.0 -32300.0 -0.28 324000.0 -76500.0 -0.65 -0.6535 -0.9269 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C17 compound treatment 431290.0 1080.0 0.01 263880.0 -137000.0 -1.16 -0.8131 -0.7015 3221238 PK04_130057 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccc(O)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C18 compound treatment 234920.0 -195000.0 -1.66 201190.0 -199000.0 -1.69 -2.3704 -1.0 3080228 PK04_130058 OCCC[C@@H](O)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C19 compound treatment 280250.0 -150000.0 -1.28 263770.0 -137000.0 -1.16 -1.7223 -0.9989 2019457 PK04_130059 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3coc4ccccc4c3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C20 compound treatment 377120.0 -53100.0 -0.45 296830.0 -104000.0 -0.88 -0.9413 -0.952 3080205 PK04_130060 OCCC[C@@H](O)c1ccc(O)c(F)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C21 compound treatment 326640.0 -104000.0 -0.88 347410.0 -53100.0 -0.45 -0.9416 -0.9515 3221241 PK04_130061 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4cccs4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C22 compound treatment 358600.0 -71600.0 -0.61 355970.0 -44600.0 -0.38 -0.698 -0.9736 3211908 PK04_130062 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C23 compound treatment 416320.0 -13900.0 -0.12 346090.0 -54400.0 -0.46 -0.41 -0.8603 2019323 PK04_130063 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 C24 compound treatment 346400.0 -83800.0 -0.71 380020.0 -20500.0 -0.17 -0.6271 -0.8545 3211812 PK04_130064 C[C@@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D01 compound treatment 470830.0 40600.0 0.35 438890.0 38400.0 0.33 0.4745 0.9995 3175965 PK04_130065 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccc(I)cc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D02 compound treatment 442400.0 12200.0 0.1 329770.0 -70800.0 -0.6 -0.351 -0.5763 3221243 PK04_130066 COc1cc2c3N(C(=O)[C@@]42O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)C(C)(C)C=C(C)c3c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D03 compound treatment 439050.0 8840.0 0.08 333330.0 -67200.0 -0.57 -0.3498 -0.6085 3176379 PK04_130067 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D04 compound treatment 454750.0 24500.0 0.21 261350.0 -139000.0 -1.18 -0.6871 -0.5732 3221245 PK04_130068 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(C)c3ccccc32)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D05 compound treatment 373410.0 -56800.0 -0.48 318810.0 -81700.0 -0.69 -0.8318 -0.9844 3052839 PK04_130069 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D06 compound treatment 391800.0 -38400.0 -0.33 294470.0 -106000.0 -0.9 -0.8672 -0.906 3221246 PK04_130070 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D07 compound treatment 458820.0 28600.0 0.24 337550.0 -63000.0 -0.53 -0.2056 -0.3502 3176048 PK04_130071 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D08 compound treatment 428590.0 -1620.0 -0.01 364410.0 -36100.0 -0.31 -0.2263 -0.7381 3221248 PK04_130072 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D09 compound treatment 467680.0 37500.0 0.32 410210.0 9690.0 0.08 0.2835 0.8612 3175970 PK04_130073 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCN(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D10 compound treatment 456980.0 26800.0 0.23 438460.0 37900.0 0.32 0.3886 0.9857 3221250 PK04_130074 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D11 mock treatment 441200.0 11000.0 0.09 474110.0 73600.0 0.62 0.5075 0.8041 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D12 mock treatment 379900.0 -50300.0 -0.43 334720.0 -65800.0 -0.56 -0.6973 -0.9914 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D13 compound treatment 456090.0 25900.0 0.22 331450.0 -69100.0 -0.59 -0.2586 -0.4132 3176675 PK04_130075 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D14 compound treatment 392700.0 -37500.0 -0.32 256290.0 -144000.0 -1.22 -1.0908 -0.8627 3221251 PK04_130076 C[C@@H]1[C@H]([C@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D15 mock treatment 454900.0 24700.0 0.21 378040.0 -22500.0 -0.19 0.0137 0.0482 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D16 mock treatment 416890.0 -13300.0 -0.11 393920.0 -6600.0 -0.06 -0.1197 -0.9473 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D17 compound treatment 473980.0 43800.0 0.37 376420.0 -24100.0 -0.2 0.1187 0.2795 3052531 PK04_130077 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D18 compound treatment 470980.0 40800.0 0.35 342510.0 -58000.0 -0.49 -0.1027 -0.1706 3221253 PK04_130078 C[C@H]1[C@@H]([C@@H](CCn2cc(CCO)nn2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D19 compound treatment 308160.0 -122000.0 -1.04 282950.0 -118000.0 -1.0 -1.4394 -0.9998 3052793 PK04_130079 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D20 compound treatment 347040.0 -83200.0 -0.71 306790.0 -93700.0 -0.8 -1.0625 -0.9983 3221255 PK04_130080 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D21 compound treatment 416280.0 -13900.0 -0.12 371270.0 -29300.0 -0.25 -0.2592 -0.9428 3052828 PK04_130081 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D22 compound treatment 381440.0 -48800.0 -0.41 406660.0 6140.0 0.05 -0.2565 -0.6136 3221256 PK04_130082 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D23 compound treatment 393950.0 -36300.0 -0.31 422590.0 22100.0 0.19 -0.0857 -0.2376 3052592 PK04_130083 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 D24 compound treatment 337050.0 -93200.0 -0.79 353720.0 -46800.0 -0.4 -0.8411 -0.9489 3221257 PK04_130084 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(C)c3c2cc(C)cc3Br)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E01 mock treatment 499450.0 69200.0 0.59 443750.0 43200.0 0.37 0.6758 0.974 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E02 mock treatment 498900.0 68700.0 0.58 338690.0 -61800.0 -0.52 0.0423 0.0539 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E03 compound treatment 427170.0 -3040.0 -0.03 397760.0 -2760.0 -0.02 -0.0348 -0.9988 2019322 PK04_130085 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)Nc3ccccc3N 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E04 compound treatment 472370.0 42200.0 0.36 365330.0 -35200.0 -0.3 0.0425 0.0912 3080210 PK04_130086 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E05 compound treatment 443270.0 13100.0 0.11 240970.0 -160000.0 -1.35 -0.8784 -0.6469 3221259 PK04_130087 OCCCCCCNC(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E06 compound treatment 434800.0 4590.0 0.04 411450.0 10900.0 0.09 0.0932 0.9263 3211802 PK04_130088 OCCC[C@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E07 compound treatment 410910.0 -19300.0 -0.16 377470.0 -23100.0 -0.2 -0.2544 -0.9962 3221261 PK04_130089 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)NCc4ccc(Cl)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E08 compound treatment 317630.0 -113000.0 -0.96 446080.0 45600.0 0.39 -0.404 -0.3911 3080219 PK04_130090 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E09 mock treatment 443920.0 13700.0 0.12 461730.0 61200.0 0.52 0.4496 0.8449 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E10 mock treatment 474600.0 44400.0 0.38 338080.0 -62400.0 -0.53 -0.1075 -0.1652 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E11 compound treatment 472080.0 41900.0 0.36 441300.0 40800.0 0.35 0.4965 0.9999 3221264 PK04_130091 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cc(=O)n(c3ccccc3)n2C)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E12 compound treatment 351480.0 -78700.0 -0.67 394110.0 -6410.0 -0.05 -0.5121 -0.762 3069920 PK04_130092 O[C@@H](CC=C)c1ccc(O)c(F)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E13 compound treatment 505090.0 74900.0 0.64 404160.0 3640.0 0.03 0.4723 0.7405 3221266 PK04_130093 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4N 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E14 compound treatment 293470.0 -137000.0 -1.16 427240.0 26700.0 0.23 -0.6623 -0.5588 3211678 PK04_130094 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E15 compound treatment 443150.0 12900.0 0.11 411310.0 10800.0 0.09 0.1426 0.9958 3221269 PK04_130095 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCOCCOCCOCCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E16 compound treatment 105800.0 -324000.0 -2.76 118240.0 -282000.0 -2.39 -3.6447 -0.9975 3211906 PK04_130096 CSc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E17 mock treatment 434850.0 4640.0 0.04 291130.0 -109000.0 -0.93 -0.6282 -0.6764 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E18 mock treatment 387760.0 -42400.0 -0.36 395590.0 -4930.0 -0.04 -0.2849 -0.7838 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E19 compound treatment 361760.0 -68400.0 -0.58 319250.0 -81300.0 -0.69 -0.8992 -0.9965 2019458 PK04_130097 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)Nc2ccccc2O)c3coc4ccccc4c3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E20 compound treatment 359160.0 -71000.0 -0.6 276970.0 -124000.0 -1.05 -1.1685 -0.9658 3211804 PK04_130098 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E21 compound treatment 345470.0 -84700.0 -0.72 423640.0 23100.0 0.2 -0.3711 -0.4967 3221271 PK04_130099 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccccc2F)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E22 compound treatment 432700.0 2490.0 0.02 431330.0 30800.0 0.26 0.1998 0.762 3211680 PK04_130100 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OC)c(O)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E23 compound treatment 288420.0 -142000.0 -1.21 331920.0 -68600.0 -0.58 -1.2644 -0.9441 2019464 PK04_130101 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCCCCCC2)c3coc4ccccc4c3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 E24 compound treatment 307920.0 -122000.0 -1.04 337470.0 -63100.0 -0.53 -1.1138 -0.9522 3211909 PK04_130102 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F01 mock treatment 441170.0 11000.0 0.09 455160.0 54600.0 0.46 0.3937 0.8327 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F02 mock treatment 455370.0 25200.0 0.21 378280.0 -22200.0 -0.19 0.018 0.0629 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F03 compound treatment 396480.0 -33700.0 -0.29 363230.0 -37300.0 -0.32 -0.4266 -0.9988 3176785 PK04_130103 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F04 compound treatment 404880.0 -25300.0 -0.22 273490.0 -127000.0 -1.08 -0.9143 -0.832 3221273 PK04_130104 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5c4cc(C)cc5Br)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F05 compound treatment 437920.0 7710.0 0.07 289120.0 -111000.0 -0.95 -0.6218 -0.6564 3176500 PK04_130105 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F06 compound treatment 447040.0 16800.0 0.14 204980.0 -196000.0 -1.66 -1.0716 -0.6437 3221274 PK04_130106 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(CC=C)c4ccccc43)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F07 compound treatment 417680.0 -12500.0 -0.11 320060.0 -80500.0 -0.68 -0.558 -0.8077 3052886 PK04_130107 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F08 compound treatment 482440.0 52200.0 0.44 336970.0 -63600.0 -0.54 -0.067 -0.0959 3221275 PK04_130108 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F09 mock treatment 356640.0 -73600.0 -0.63 432000.0 31500.0 0.27 -0.2537 -0.3729 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F10 mock treatment 430740.0 534.0 0.0 441760.0 41200.0 0.35 0.2506 0.7162 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F11 compound treatment 398530.0 -31700.0 -0.27 415330.0 14800.0 0.13 -0.1017 -0.3422 3052654 PK04_130109 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F12 compound treatment 447770.0 17600.0 0.15 409500.0 8980.0 0.08 0.1595 0.9511 3221277 PK04_130110 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F13 compound treatment 430680.0 474.0 0.0 438130.0 37600.0 0.32 0.2284 0.716 3052647 PK04_130111 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F14 compound treatment 243210.0 -187000.0 -1.59 407610.0 7090.0 0.06 -1.0824 -0.6799 3221279 PK04_130112 C[C@H]1[C@@H]([C@@H](CC(=O)N2Cc3ccccc3C[C@H]2CO)O[C@]14C(=O)N(C)c5ccccc54)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F15 compound treatment 379840.0 -50400.0 -0.43 246590.0 -154000.0 -1.31 -1.2263 -0.8923 3176113 PK04_130113 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F16 compound treatment 245600.0 -185000.0 -1.57 270320.0 -130000.0 -1.1 -1.8915 -0.9852 3221280 PK04_130114 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F17 mock treatment 351780.0 -78400.0 -0.67 432160.0 31600.0 0.27 -0.282 -0.3922 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F18 mock treatment 465330.0 35100.0 0.3 289060.0 -111000.0 -0.95 -0.4573 -0.4612 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F19 compound treatment 310610.0 -120000.0 -1.02 424670.0 24100.0 0.2 -0.5746 -0.5536 3052888 PK04_130115 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F20 compound treatment 253360.0 -177000.0 -1.5 286940.0 -114000.0 -0.96 -1.7451 -0.9768 3221282 PK04_130116 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(c3ccccc32)c4ccccc4)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F21 compound treatment 432320.0 2110.0 0.02 467530.0 67000.0 0.57 0.4146 0.7291 3176499 PK04_130117 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F22 compound treatment 437440.0 7230.0 0.06 288090.0 -112000.0 -0.95 -0.6309 -0.6601 3221283 PK04_130118 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F23 compound treatment 431090.0 884.0 0.01 455090.0 54600.0 0.46 0.3326 0.7185 3175968 PK04_130119 CC(=O)NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 F24 compound treatment 408740.0 -21500.0 -0.18 396320.0 -4200.0 -0.04 -0.1543 -0.8295 3221284 PK04_130120 C[C@@H]1[C@H]([C@H](CC(=O)N2CCC[C@H]2CO)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G01 compound treatment 469830.0 39600.0 0.34 311650.0 -88900.0 -0.75 -0.2947 -0.3569 2019328 PK04_130121 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)N3CCOCCOCCOCCOCC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G02 compound treatment 224880.0 -205000.0 -1.75 114080.0 -286000.0 -2.43 -2.9533 -0.9869 3211907 PK04_130122 COc1ccc(NC(=O)O[C@@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G03 mock treatment 477460.0 47300.0 0.4 320260.0 -80300.0 -0.68 -0.1972 -0.2494 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G04 mock treatment 463750.0 33500.0 0.29 350340.0 -50200.0 -0.43 -0.0992 -0.1936 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G05 compound treatment 460180.0 30000.0 0.25 370460.0 -30100.0 -0.26 0.0 0.0 3221285 PK04_130123 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCCCCCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G06 compound treatment 425070.0 -5140.0 -0.04 350120.0 -50400.0 -0.43 -0.3332 -0.7753 3211815 PK04_130124 COc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G07 compound treatment 413730.0 -16500.0 -0.14 278880.0 -122000.0 -1.03 -0.8288 -0.7959 3221287 PK04_130125 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)NCc3ccccc3F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G08 compound treatment 431850.0 1640.0 0.01 361150.0 -39400.0 -0.33 -0.2263 -0.6769 3211803 PK04_130126 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G09 compound treatment 478760.0 48600.0 0.41 387680.0 -12800.0 -0.11 0.215 0.5034 3221289 PK04_130127 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)N4CCCCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G10 compound treatment 458810.0 28600.0 0.24 406810.0 6290.0 0.05 0.2098 0.8421 3211807 PK04_130128 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G11 compound treatment 324480.0 -106000.0 -0.9 408960.0 8440.0 0.07 -0.5854 -0.6488 2019311 PK04_130129 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2ccc(cc2)C(=O)OC)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G12 compound treatment 340880.0 -89300.0 -0.76 404710.0 4190.0 0.04 -0.5122 -0.6733 3211818 PK04_130130 COc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G13 compound treatment 350590.0 -79600.0 -0.68 394630.0 -5890.0 -0.05 -0.5143 -0.7572 3221292 PK04_130131 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)Nc4ccccc4O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G14 compound treatment 445320.0 15100.0 0.13 328740.0 -71800.0 -0.61 -0.3397 -0.5458 3080207 PK04_130132 OCCC[C@H](O)c1ccc(O)c(F)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G15 compound treatment 383810.0 -46400.0 -0.39 334720.0 -65800.0 -0.56 -0.6738 -0.9856 2019470 PK04_130133 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)O)c2coc3ccccc3c2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G16 compound treatment 383390.0 -46800.0 -0.4 265610.0 -135000.0 -1.14 -1.0909 -0.9002 3080225 PK04_130134 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G17 compound treatment 283120.0 -147000.0 -1.25 299000.0 -102000.0 -0.86 -1.4938 -0.9834 3221294 PK04_130135 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c4coc5ccccc5c4=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G18 compound treatment 343930.0 -86300.0 -0.73 346210.0 -54300.0 -0.46 -0.8448 -0.9748 3211806 PK04_130136 CO[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G19 mock treatment 446240.0 16000.0 0.14 370560.0 -30000.0 -0.25 -0.0833 -0.2887 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G20 mock treatment 393820.0 -36400.0 -0.31 402760.0 2240.0 0.02 -0.2055 -0.6625 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G21 compound treatment 364900.0 -65300.0 -0.56 334320.0 -66200.0 -0.56 -0.79 -1.0 2019463 PK04_130137 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)N2CCOCCOCCOCCOCC2)c3coc4ccccc4c3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G22 compound treatment 397140.0 -33100.0 -0.28 381960.0 -18600.0 -0.16 -0.3103 -0.9624 3080280 PK04_130138 COc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G23 compound treatment 462880.0 32700.0 0.28 434880.0 34400.0 0.29 0.4026 0.9997 3221297 PK04_130139 Cn1c(cc(=O)n1c2ccccc2)[C@@H]3C[C@H](OCCCCO)OC(=C3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 G24 compound treatment 238840.0 -191000.0 -1.63 383760.0 -16800.0 -0.14 -1.2517 -0.766 3211912 PK04_130140 C[C@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H01 compound treatment 444070.0 13900.0 0.12 413880.0 13400.0 0.11 0.1635 0.9998 3052931 PK04_130141 NCCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H02 compound treatment 399920.0 -30300.0 -0.26 249850.0 -151000.0 -1.28 -1.086 -0.8329 3221300 PK04_130142 C[C@@H]1[C@H]([C@H](CCn2cc(CCO)nn2)O[C@@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H03 mock treatment 468040.0 37800.0 0.32 219040.0 -181000.0 -1.54 -0.861 -0.5474 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H04 mock treatment 377850.0 -52400.0 -0.45 407610.0 7090.0 0.06 -0.2724 -0.6062 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H05 compound treatment 368120.0 -62100.0 -0.53 297870.0 -103000.0 -0.87 -0.9892 -0.9713 3176330 PK04_130143 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H06 compound treatment 464160.0 34000.0 0.29 353060.0 -47500.0 -0.4 -0.0804 -0.1623 3221301 PK04_130144 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(c4ccccc43)c5ccccc5)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H07 compound treatment 368060.0 -62100.0 -0.53 375610.0 -24900.0 -0.21 -0.5233 -0.9191 3176685 PK04_130145 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H08 compound treatment 417310.0 -12900.0 -0.11 427080.0 26600.0 0.23 0.0817 0.3261 3221302 PK04_130146 C[C@H]1[C@@H]([C@@H](CC(=O)N2CCC[C@H]2CO)O[C@]13C(=O)N(C)c4ccccc43)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H09 compound treatment 383730.0 -46500.0 -0.4 428990.0 28500.0 0.24 -0.1088 -0.2349 3052879 PK04_130147 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H10 compound treatment 450480.0 20300.0 0.17 387640.0 -12900.0 -0.11 0.0447 0.2188 3221303 PK04_130148 C[C@H]1[C@@H]([C@@H](CC(=O)N(CCO)Cc2ccccc2)O[C@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H11 compound treatment 421940.0 -8270.0 -0.07 425470.0 24900.0 0.21 0.0999 0.448 3176775 PK04_130149 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H12 compound treatment 438090.0 7880.0 0.07 373120.0 -27400.0 -0.23 -0.1169 -0.4834 3221305 PK04_130150 COc1cc2c3N(C(=O)[C@]42O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)O)C(C)(C)C=C(C)c3c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H13 compound treatment 315760.0 -114000.0 -0.97 362340.0 -38200.0 -0.32 -0.9175 -0.8942 3052783 PK04_130151 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H14 compound treatment 337870.0 -92300.0 -0.79 236420.0 -164000.0 -1.39 -1.5398 -0.9633 3221307 PK04_130152 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(CC=C)c5ccccc54)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H15 compound treatment 407680.0 -22500.0 -0.19 381790.0 -18700.0 -0.16 -0.2479 -0.9957 3176626 PK04_130153 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)NCc5ccc(F)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H16 compound treatment 328810.0 -101000.0 -0.86 316480.0 -84000.0 -0.71 -1.1141 -0.9955 3221308 PK04_130154 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccccc32)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H17 compound treatment 402530.0 -27700.0 -0.24 407700.0 7180.0 0.06 -0.1234 -0.5076 3176501 PK04_130155 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCCCN(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H18 compound treatment 427490.0 -2720.0 -0.02 377760.0 -22800.0 -0.19 -0.1529 -0.7861 3221309 PK04_130156 C[C@@H]1[C@H]([C@H](CC(=O)N(CCO)Cc2ccccc2)O[C@@]13C(=O)N(C)c4c3cc(C)cc4Br)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H19 mock treatment 418520.0 -11700.0 -0.1 446160.0 45600.0 0.39 0.2034 0.509 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H20 mock treatment 472030.0 41800.0 0.36 405230.0 4710.0 0.04 0.2798 0.7815 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H21 compound treatment 386660.0 -43500.0 -0.37 440700.0 40200.0 0.34 -0.021 -0.0417 3052741 PK04_130157 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H22 compound treatment 256060.0 -174000.0 -1.48 293390.0 -107000.0 -0.91 -1.6902 -0.9725 3221310 PK04_130158 C[C@@H]1[C@H]([C@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H23 compound treatment 402650.0 -27600.0 -0.23 332180.0 -68300.0 -0.58 -0.5757 -0.9206 3176203 PK04_130159 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 H24 compound treatment 375160.0 -55000.0 -0.47 344180.0 -56300.0 -0.48 -0.6691 -0.9999 3221312 PK04_130160 C[C@H]1[C@@H]([C@@H](CCn2cc(nn2)[C@H](O)c3ccccc3)O[C@]14C(=O)N(c5ccccc54)c6ccccc6)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I01 compound treatment 435160.0 4950.0 0.04 429840.0 29300.0 0.25 0.2056 0.8153 3221313 PK04_130161 OCCCCO[C@H]1C[C@H](C=C(O1)C(=O)NCc2ccc(Cl)cc2)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I02 compound treatment 393980.0 -36200.0 -0.31 360320.0 -40200.0 -0.34 -0.4591 -0.9987 3080209 PK04_130162 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(O)c(F)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I03 compound treatment 440260.0 10100.0 0.09 334750.0 -65800.0 -0.56 -0.334 -0.5918 3221314 PK04_130163 Nc1ccccc1NC(=O)C2=C[C@@H](C[C@H](OCCCCO)O2)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I04 compound treatment 452690.0 22500.0 0.19 375970.0 -24600.0 -0.21 -0.012 -0.0425 3069956 PK04_130164 CO[C@@H](C=C)[C@@H](O)c1ccc(OC)c(O)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I05 mock treatment 465980.0 35800.0 0.3 299230.0 -101000.0 -0.86 -0.3924 -0.4305 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I06 mock treatment 451040.0 20800.0 0.18 287000.0 -114000.0 -0.96 -0.5556 -0.5674 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I07 compound treatment 370000.0 -60200.0 -0.51 372360.0 -28200.0 -0.24 -0.5311 -0.9397 3221316 PK04_130165 COC(CN(C)C(=O)C1=C[C@@H](C[C@H](OCCCCO)O1)c2cccs2)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I08 compound treatment 466620.0 36400.0 0.31 325930.0 -74600.0 -0.63 -0.2284 -0.3242 3211693 PK04_130166 CO[C@H](CCO)[C@H](O)c1ccc(O)c(F)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I09 compound treatment 441810.0 11600.0 0.1 375550.0 -25000.0 -0.21 -0.08 -0.3423 2019335 PK04_130167 COC(=O)c1ccc(cc1)[C@@H]2C[C@H](OCCCCO)OC(=C2)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I10 compound treatment 417920.0 -12300.0 -0.1 392480.0 -8040.0 -0.07 -0.1222 -0.9786 3080278 PK04_130168 CSc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I11 compound treatment 491890.0 61700.0 0.52 266850.0 -134000.0 -1.13 -0.4307 -0.3447 3221318 PK04_130169 COc1cc2c[n+](Cc3cc4OCOc4cc3Br)ccc2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I12 compound treatment 419970.0 -10200.0 -0.09 416600.0 16100.0 0.14 0.0349 0.2154 3211911 PK04_130170 COc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I13 compound treatment 459080.0 28900.0 0.25 470290.0 69800.0 0.59 0.5922 0.9242 3221319 PK04_130171 COc1cc2c[n+](Cc3sc4ccccc4c3Cl)ccc2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I14 compound treatment 450440.0 20200.0 0.17 437980.0 37500.0 0.32 0.3464 0.9586 3080208 PK04_130172 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I15 compound treatment 449610.0 19400.0 0.17 421920.0 21400.0 0.18 0.2451 0.9989 3221320 PK04_130173 COc1cc2c[n+](Cc3ccc(o3)[N+](=O)[O-])ccc2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I16 compound treatment 480170.0 50000.0 0.43 494340.0 93800.0 0.8 0.8633 0.9568 3080223 PK04_130174 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(OC)cc1)c2ccc(OCCO)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I17 compound treatment 430160.0 -46.5 0.0 404760.0 4240.0 0.04 0.0251 0.6993 3221321 PK04_130175 COc1cc2c[n+](Cc3cccc(OC(F)(F)F)c3)ccc2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I18 compound treatment 123550.0 -307000.0 -2.61 114720.0 -286000.0 -2.42 -3.559 -0.9993 3080282 PK04_130176 CSc1ccc(NC(=O)O[C@H]([C@H](C)C=C)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I19 compound treatment 361070.0 -69100.0 -0.59 301960.0 -98600.0 -0.84 -1.0071 -0.9852 3221322 PK04_130177 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)CCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I20 compound treatment 428380.0 -1830.0 -0.02 404370.0 3850.0 0.03 0.0121 0.3344 3211594 PK04_130178 CO[C@H](C=C)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I21 mock treatment 371900.0 -58300.0 -0.5 398840.0 -1680.0 -0.01 -0.3608 -0.7272 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I22 mock treatment 456400.0 26200.0 0.22 442080.0 41600.0 0.35 0.4068 0.9755 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I23 compound treatment 387800.0 -42400.0 -0.36 308650.0 -91900.0 -0.78 -0.8062 -0.9387 3221324 PK04_130179 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4cccs4)CCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 I24 compound treatment 367060.0 -63100.0 -0.54 353440.0 -47100.0 -0.4 -0.6623 -0.9893 3211811 PK04_130180 CSc1ccc(NC(=O)O[C@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J01 compound treatment 434840.0 4630.0 0.04 398960.0 -1560.0 -0.01 0.0185 0.4447 3176788 PK04_130181 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J02 compound treatment 421440.0 -8770.0 -0.07 215010.0 -186000.0 -1.57 -1.1655 -0.7398 3221326 PK04_130182 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J03 compound treatment 367680.0 -62500.0 -0.53 306450.0 -94100.0 -0.8 -0.9404 -0.9806 3176789 PK04_130183 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J04 compound treatment 436910.0 6700.0 0.06 267060.0 -133000.0 -1.13 -0.7602 -0.6706 3221328 PK04_130184 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J05 mock treatment 435680.0 5470.0 0.05 316030.0 -84500.0 -0.72 -0.4739 -0.6598 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J06 mock treatment 347900.0 -82300.0 -0.7 346810.0 -53700.0 -0.46 -0.8173 -0.9783 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J07 compound treatment 278210.0 -152000.0 -1.29 219390.0 -181000.0 -1.54 -2.0008 -0.9963 3052827 PK04_130185 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J08 compound treatment 342930.0 -87300.0 -0.74 187390.0 -213000.0 -1.81 -1.8034 -0.9227 3221330 PK04_130186 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J09 compound treatment 477390.0 47200.0 0.4 378140.0 -22400.0 -0.19 0.1496 0.3368 3052794 PK04_130187 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J10 compound treatment 448700.0 18500.0 0.16 411480.0 11000.0 0.09 0.177 0.9685 3221332 PK04_130188 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J11 compound treatment 375570.0 -54600.0 -0.46 378880.0 -21600.0 -0.18 -0.4585 -0.9174 3176437 PK04_130189 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J12 compound treatment 238240.0 -192000.0 -1.63 277920.0 -123000.0 -1.04 -1.8902 -0.9763 3221334 PK04_130190 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCOC4=O)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J13 compound treatment 484580.0 54400.0 0.46 296580.0 -104000.0 -0.88 -0.2964 -0.2977 3176038 PK04_130191 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J14 compound treatment 232480.0 -198000.0 -1.68 176440.0 -224000.0 -1.9 -2.5335 -0.9981 3221335 PK04_130192 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCC4=O)c5ccccc52)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J15 compound treatment 404020.0 -26200.0 -0.22 464800.0 64300.0 0.55 0.228 0.3871 3052796 PK04_130193 Oc1ccc(cc1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@H](Cc4ccccc4)NC3=O)C(=O)NCc5ccc(F)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J16 compound treatment 248750.0 -181000.0 -1.54 215700.0 -185000.0 -1.57 -2.2002 -1.0 3221337 PK04_130194 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J17 compound treatment 433710.0 3500.0 0.03 424320.0 23800.0 0.2 0.1638 0.8028 3176331 PK04_130195 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J18 compound treatment 290940.0 -139000.0 -1.18 251520.0 -149000.0 -1.26 -1.7315 -0.9995 3221339 PK04_130196 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J19 compound treatment 429060.0 -1150.0 -0.01 458090.0 57600.0 0.49 0.3384 0.6928 3176671 PK04_130197 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J20 compound treatment 387130.0 -43100.0 -0.37 236800.0 -164000.0 -1.39 -1.2412 -0.8641 3221341 PK04_130198 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5ccccc5Oc6ccccc46)c7ccccc72)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J21 mock treatment 415700.0 -14500.0 -0.12 384000.0 -16500.0 -0.14 -0.1864 -0.998 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J22 mock treatment 420100.0 -10100.0 -0.09 399680.0 -843.0 -0.01 -0.0659 -0.7633 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J23 compound treatment 344870.0 -85300.0 -0.73 359690.0 -40800.0 -0.35 -0.7583 -0.9427 3176271 PK04_130199 OCCOc1cccc(c1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 J24 compound treatment 334440.0 -95800.0 -0.81 277530.0 -123000.0 -1.04 -1.3138 -0.9925 3221343 PK04_130200 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5ccccc5Oc6ccccc46)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K01 compound treatment 487010.0 56800.0 0.48 374160.0 -26400.0 -0.22 0.1836 0.3448 3221345 PK04_130201 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3cccs3)c4ccc(CO)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K02 compound treatment 372840.0 -57400.0 -0.49 317360.0 -83200.0 -0.71 -0.8439 -0.9838 3211905 PK04_130202 C[C@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K03 compound treatment 450010.0 19800.0 0.17 232690.0 -168000.0 -1.42 -0.8876 -0.6191 3221347 PK04_130203 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#Cc4ccccc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K04 compound treatment 430190.0 -16.5 0.0 383760.0 -16800.0 -0.14 -0.1006 -0.7078 3211691 PK04_130204 CSc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c(F)c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K05 compound treatment 416970.0 -13200.0 -0.11 416100.0 15600.0 0.13 0.0138 0.0795 3221348 PK04_130205 COc1cc2CCN(C)C(C#Cc3ccccc3)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K06 compound treatment 393070.0 -37100.0 -0.32 424750.0 24200.0 0.21 -0.0781 -0.2072 3211813 PK04_130206 CSc1ccc(NC(=O)O[C@@H]([C@@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K07 mock treatment 451420.0 21200.0 0.18 420640.0 20100.0 0.17 0.2483 0.9996 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K08 mock treatment 510240.0 80000.0 0.68 417890.0 17400.0 0.15 0.5856 0.8406 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K09 compound treatment 293790.0 -136000.0 -1.16 300010.0 -101000.0 -0.85 -1.4235 -0.9885 3221349 PK04_130207 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#Cc4ccccc4)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K10 compound treatment 178080.0 -252000.0 -2.14 232980.0 -168000.0 -1.42 -2.5216 -0.98 3211817 PK04_130208 CSc1ccc(NC(=O)O[C@H](CC=C)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K11 compound treatment 317490.0 -113000.0 -0.96 275540.0 -125000.0 -1.06 -1.4277 -0.9987 3221350 PK04_130209 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(O)cc13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K12 compound treatment 391480.0 -38700.0 -0.33 351580.0 -48900.0 -0.42 -0.5265 -0.9934 3080279 PK04_130210 C[C@@H](CCO)[C@@H](O)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K13 compound treatment 388320.0 -41900.0 -0.36 438730.0 38200.0 0.32 -0.0228 -0.0473 3221351 PK04_130211 COCC#CC1N(C)CCc2cc(OC)c(O)cc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K14 compound treatment 516690.0 86500.0 0.74 406990.0 6470.0 0.05 0.559 0.7577 3080188 PK04_130212 CO[C@H](CCO)[C@H](O)c1ccc(OC)c(O)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K15 mock treatment 458670.0 28500.0 0.24 491440.0 90900.0 0.77 0.7166 0.8865 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K16 mock treatment 491440.0 61200.0 0.52 514200.0 114000.0 0.96 1.0502 0.9582 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K17 compound treatment 436480.0 6270.0 0.05 411480.0 11000.0 0.09 0.1035 0.9653 3221353 PK04_130213 COCC#CC1N(Cc2ccc(o2)[N+](=O)[O-])CCc3cc(OC)c(O)cc13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K18 compound treatment 427540.0 -2670.0 -0.02 385770.0 -14800.0 -0.13 -0.1045 -0.8219 3080221 PK04_130214 CO[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K19 compound treatment 286940.0 -143000.0 -1.22 306040.0 -94500.0 -0.8 -1.4286 -0.9793 3221354 PK04_130215 COc1ccc(CN2CCc3cc(OC)c(O)cc3C2C#C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K20 compound treatment 483240.0 53000.0 0.45 443940.0 43400.0 0.37 0.5794 0.9949 3211696 PK04_130216 CO[C@@H](CCO)[C@@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K21 compound treatment 341870.0 -88300.0 -0.75 317390.0 -83100.0 -0.71 -1.03 -0.9995 3221356 PK04_130217 COc1cc2CCN(C)C(C#C)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K22 compound treatment 431210.0 1000.0 0.01 430030.0 29500.0 0.25 0.183 0.7308 3211816 PK04_130218 COc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K23 mock treatment 444390.0 14200.0 0.12 462170.0 61600.0 0.52 0.4551 0.848 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 K24 mock treatment 503880.0 73700.0 0.63 453600.0 53100.0 0.45 0.7616 0.9868 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L01 compound treatment 467540.0 37300.0 0.32 436000.0 35500.0 0.3 0.4374 0.9996 3176382 PK04_130219 CN(C)CCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L02 compound treatment 496000.0 65800.0 0.56 367520.0 -33000.0 -0.28 0.1978 0.3161 3221357 PK04_130220 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCCCC4=O)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L03 compound treatment 438420.0 8210.0 0.07 443000.0 42500.0 0.36 0.3042 0.8288 3176383 PK04_130221 NCCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L04 compound treatment 402770.0 -27400.0 -0.23 274530.0 -126000.0 -1.07 -0.9208 -0.8417 3221359 PK04_130222 C[C@H](O)C(=O)Nc1ccc2N(CC=C)C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L05 compound treatment 404480.0 -25700.0 -0.22 407630.0 7110.0 0.06 -0.1121 -0.4939 3052642 PK04_130223 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)[C@@H]4CCCN4C3=O)C(=O)OCCOc5ccc(cc5)[C@H]6N7[C@@H]([C@@H](C(=O)OCC=C)[C@]68C(=O)Nc9ccccc98)C(=O)O[C@@H]([C@@H]7c%10ccccc%10)c%11ccccc%11 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L06 compound treatment 342670.0 -87500.0 -0.74 363910.0 -36600.0 -0.31 -0.7462 -0.9248 3221361 PK04_130224 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L07 mock treatment 481050.0 50800.0 0.43 425120.0 24600.0 0.21 0.4534 0.9441 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L08 mock treatment 463730.0 33500.0 0.29 459610.0 59100.0 0.5 0.5561 0.9643 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L09 compound treatment 454280.0 24100.0 0.2 353140.0 -47400.0 -0.4 -0.1394 -0.309 3176673 PK04_130225 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L10 compound treatment 307310.0 -123000.0 -1.05 249020.0 -152000.0 -1.29 -1.648 -0.9948 3221363 PK04_130226 COc1ccc(cc1)C(=O)Nc2cccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L11 compound treatment 395540.0 -34700.0 -0.29 402400.0 1880.0 0.02 -0.1973 -0.668 3052529 PK04_130227 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L12 compound treatment 507770.0 77600.0 0.66 321140.0 -79400.0 -0.67 -0.0096 -0.0101 3221365 PK04_130228 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N(C=O)c4ccccc4)c5ccccc52)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L13 compound treatment 401370.0 -28800.0 -0.25 342810.0 -57700.0 -0.49 -0.5196 -0.949 3052693 PK04_130229 CN(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L14 compound treatment 344660.0 -85500.0 -0.73 226500.0 -174000.0 -1.48 -1.5584 -0.9469 3221366 PK04_130230 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L15 mock treatment 478470.0 48300.0 0.41 465060.0 64500.0 0.55 0.6774 0.99 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L16 mock treatment 456960.0 26800.0 0.23 454900.0 54400.0 0.46 0.4871 0.947 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L17 compound treatment 456020.0 25800.0 0.22 405190.0 4670.0 0.04 0.1833 0.8213 3176205 PK04_130231 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L18 compound treatment 332120.0 -98100.0 -0.83 272740.0 -128000.0 -1.08 -1.3565 -0.9916 3221368 PK04_130232 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCOC4=O)c5ccccc52)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L19 compound treatment 464290.0 34100.0 0.29 382410.0 -18100.0 -0.15 0.0964 0.2937 3176125 PK04_130233 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L20 compound treatment 391200.0 -39000.0 -0.33 312010.0 -88500.0 -0.75 -0.7656 -0.9326 3221370 PK04_130234 COc1ccc(cc1)C(=O)Nc2ccc3N(CC=C)C(=O)[C@@]4(O[C@@H](CCO)[C@@H]([C@H]4C)[Si](C)(C)F)c3c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L21 compound treatment 433440.0 3230.0 0.03 323410.0 -77100.0 -0.65 -0.4431 -0.6768 3052877 PK04_130235 Oc1ccc(cc1)[C@H]2[C@H](C[C@@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L22 compound treatment 301800.0 -128000.0 -1.09 206080.0 -194000.0 -1.65 -1.9387 -0.98 3221372 PK04_130236 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(NC(=O)C)cc32)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L23 mock treatment 507440.0 77200.0 0.66 345570.0 -55000.0 -0.47 0.135 0.1676 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 L24 mock treatment 338990.0 -91200.0 -0.78 456320.0 55800.0 0.47 -0.214 -0.2355 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M01 compound treatment 306950.0 -123000.0 -1.05 317690.0 -82800.0 -0.7 -1.2383 -0.981 3221374 PK04_130237 COc1cc2CCN(Cc3ccc(o3)[N+](=O)[O-])C(C#C)c2cc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M02 compound treatment 513890.0 83700.0 0.71 287490.0 -113000.0 -0.96 -0.1746 -0.1462 3211810 PK04_130238 C[C@@H](CCO)[C@@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M03 compound treatment 467160.0 37000.0 0.31 461940.0 61400.0 0.52 0.5907 0.9707 3221375 PK04_130239 CC(C)C(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M04 compound treatment 445020.0 14800.0 0.13 442780.0 42300.0 0.36 0.3426 0.9016 3080224 PK04_130240 COc1ccc(NC(=O)O[C@@H]([C@H](C)CCO)c2ccc(OCCO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M05 compound treatment 480410.0 50200.0 0.43 422150.0 21600.0 0.18 0.4317 0.9288 3221376 PK04_130241 COCC(=C=CC[C@@H](O)c1ccc(OCCO)cc1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M06 compound treatment 432320.0 2110.0 0.02 348070.0 -52500.0 -0.44 -0.3019 -0.678 3211820 PK04_130242 COc1ccc(NC(=O)O[C@@H](CCCO)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M07 compound treatment 417280.0 -12900.0 -0.11 445360.0 44800.0 0.38 0.1912 0.4829 3221377 PK04_130243 CCCCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M08 compound treatment 433120.0 2910.0 0.02 386790.0 -13700.0 -0.12 -0.0648 -0.5445 3211694 PK04_130244 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(O)c(F)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M09 mock treatment 495360.0 65200.0 0.55 464680.0 64200.0 0.54 0.7768 1.0 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M10 mock treatment 482640.0 52400.0 0.45 486640.0 86100.0 0.73 0.832 0.972 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M11 compound treatment 399800.0 -30400.0 -0.26 396730.0 -3790.0 -0.03 -0.2057 -0.789 3221378 PK04_130245 CC(C)C(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M12 compound treatment 450880.0 20700.0 0.18 476770.0 76200.0 0.65 0.5817 0.8679 3080189 PK04_130246 CO[C@H](CCO)[C@H](OC(=O)Nc1ccc(SC)cc1)c2ccc(OC)c(O)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M13 mock treatment 466810.0 36600.0 0.31 476590.0 76100.0 0.65 0.6765 0.9442 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M14 mock treatment 420060.0 -10100.0 -0.09 433790.0 33300.0 0.28 0.1385 0.4693 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M15 compound treatment 459410.0 29200.0 0.25 436670.0 36100.0 0.31 0.3925 0.9946 3221379 PK04_130247 COCC(=C=CC[C@@H](O)c1cccc(OCCO)c1)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M16 compound treatment 417810.0 -12400.0 -0.11 493800.0 93300.0 0.79 0.4849 0.6075 3211679 PK04_130248 CO[C@@H](CCO)[C@@H](O)c1ccc(OC)c(O)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M17 compound treatment 446280.0 16100.0 0.14 414880.0 14400.0 0.12 0.1828 0.9983 3221380 PK04_130249 CCCCC(=C=CC[C@@H](O)c1ccccc1OCCO)C[C@@H](O)c2cc(Cl)cc(Cl)c2O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M18 compound treatment 454350.0 24100.0 0.21 407900.0 7380.0 0.06 0.1895 0.8825 3211808 PK04_130250 C[C@H](CCO)[C@H](O)c1ccc(OCCO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M19 mock treatment 427310.0 -2900.0 -0.02 435840.0 35300.0 0.3 0.1944 0.6468 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M20 compound treatment 407730.0 -22500.0 -0.19 348030.0 -52500.0 -0.45 -0.4501 -0.9287 3080271 PK04_130251 CSc1ccc(NC(=O)O[C@H](CCCO)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M21 mock treatment 448700.0 18500.0 0.16 355330.0 -45200.0 -0.38 -0.1598 -0.3857 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M22 compound treatment 413730.0 -16500.0 -0.14 423080.0 22600.0 0.19 0.0362 0.1526 3211910 PK04_130252 C[C@@H](CCO)[C@H](O)c1ccc(O)c2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M23 mock treatment 388800.0 -41400.0 -0.35 428640.0 28100.0 0.24 -0.0804 -0.1891 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 M24 compound treatment 353290.0 -76900.0 -0.65 367960.0 -32600.0 -0.28 -0.658 -0.9264 3211692 PK04_130253 COc1ccc(NC(=O)O[C@@H](CC=C)c2ccc(O)c(F)c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N01 compound treatment 424810.0 -5400.0 -0.05 317440.0 -83100.0 -0.7 -0.5308 -0.7516 3176433 PK04_130254 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N02 compound treatment 282510.0 -148000.0 -1.26 220200.0 -180000.0 -1.53 -1.9701 -0.9952 3221382 PK04_130255 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCCCC5=O)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N03 compound treatment 469120.0 38900.0 0.33 461280.0 60800.0 0.52 0.5985 0.9771 3175967 PK04_130256 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N04 compound treatment 466530.0 36300.0 0.31 483610.0 83100.0 0.7 0.7169 0.9315 3221383 PK04_130257 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N05 compound treatment 355200.0 -75000.0 -0.64 466720.0 66200.0 0.56 -0.0541 -0.0637 3052653 PK04_130258 OCCOc1cccc(c1)[C@@H]2[C@@H](C[C@H]3N2C(=O)CNC3=O)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N06 compound treatment 453700.0 23500.0 0.2 437790.0 37300.0 0.32 0.3649 0.9755 3221385 PK04_130259 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(CC=C)c3ccc(cc32)N4C(=O)c5cccc6cccc4c56)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N07 compound treatment 459270.0 29100.0 0.25 441980.0 41500.0 0.35 0.4235 0.9851 3052758 PK04_130260 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCCN(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N08 compound treatment 383900.0 -46300.0 -0.39 366560.0 -34000.0 -0.29 -0.4823 -0.9882 3221386 PK04_130261 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N09 mock treatment 391280.0 -38900.0 -0.33 517310.0 117000.0 0.99 0.4663 0.4465 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N10 mock treatment 469570.0 39400.0 0.33 490420.0 89900.0 0.76 0.776 0.9317 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N11 compound treatment 443640.0 13400.0 0.11 457790.0 57300.0 0.49 0.4243 0.8502 3176332 PK04_130262 CN(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N12 compound treatment 417880.0 -12300.0 -0.1 390890.0 -9630.0 -0.08 -0.1319 -0.9924 3221388 PK04_130263 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N13 mock treatment 482560.0 52400.0 0.45 476570.0 76000.0 0.65 0.7711 0.9836 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N14 mock treatment 500580.0 70400.0 0.6 449240.0 48700.0 0.41 0.7155 0.9836 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N15 compound treatment 495930.0 65700.0 0.56 464860.0 64300.0 0.55 0.7813 0.9999 3176440 PK04_130264 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCc4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N16 compound treatment 449990.0 19800.0 0.17 481640.0 81100.0 0.69 0.6056 0.8549 3221389 PK04_130265 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4C(=O)c5cccc6cccc4c56)c7ccccc72)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N17 compound treatment 490400.0 60200.0 0.51 432120.0 31600.0 0.27 0.5516 0.9544 3174818 PK04_130266 CN(C)CCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3cccc(OCCO)c3)C(=O)[C@H](CCCCNC(=O)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N18 compound treatment 300200.0 -130000.0 -1.11 280760.0 -120000.0 -1.02 -1.5004 -0.9991 3221391 PK04_130267 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCOC5=O)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N19 compound treatment 476130.0 45900.0 0.39 491300.0 90800.0 0.77 0.8208 0.9505 3052539 PK04_130268 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)NCCCCCCN(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N20 compound treatment 267120.0 -163000.0 -1.39 221540.0 -179000.0 -1.52 -2.0546 -0.999 3221392 PK04_130269 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N(C=O)c5ccccc5)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N21 compound treatment 445760.0 15600.0 0.13 426960.0 26400.0 0.22 0.2521 0.9683 3052582 PK04_130270 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N22 compound treatment 389120.0 -41100.0 -0.35 246150.0 -154000.0 -1.31 -1.1731 -0.8655 3221394 PK04_130271 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@@]3(O[C@@H](CCO)[C@@H]([C@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N23 compound treatment 426620.0 -3590.0 -0.03 422920.0 22400.0 0.19 0.1128 0.586 3052791 PK04_130272 CC(C)C[C@@H]1NC(=O)[C@@H]2C[C@@H]([C@@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 N24 compound treatment 210590.0 -220000.0 -1.87 365040.0 -35500.0 -0.3 -1.534 -0.8106 3221396 PK04_130273 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O01 mock treatment 415910.0 -14300.0 -0.12 327360.0 -73200.0 -0.62 -0.5248 -0.8299 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O02 compound treatment 322040.0 -108000.0 -0.92 365880.0 -34600.0 -0.29 -0.8585 -0.8887 3211913 PK04_130274 CSc1ccc(NC(=O)O[C@H]([C@H](C)CCO)c2ccc(O)c3ccccc23)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O03 mock treatment 385440.0 -44800.0 -0.38 454660.0 54100.0 0.46 0.0554 0.0929 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O04 mock treatment 439390.0 9180.0 0.08 451840.0 51300.0 0.44 0.3631 0.8209 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O05 mock treatment 432260.0 2050.0 0.02 423840.0 23300.0 0.2 0.1522 0.7666 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O06 mock treatment 370320.0 -59900.0 -0.51 366260.0 -34300.0 -0.29 -0.5658 -0.9646 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O07 mock treatment 461660.0 31500.0 0.27 428890.0 28400.0 0.24 0.3594 0.9986 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O08 mock treatment 406590.0 -23600.0 -0.2 431330.0 30800.0 0.26 0.0427 0.1296 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O09 mock treatment 425460.0 -4750.0 -0.04 344740.0 -55800.0 -0.47 -0.3632 -0.7647 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O10 mock treatment 426290.0 -3920.0 -0.03 438520.0 38000.0 0.32 0.2044 0.6307 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O11 mock treatment 394080.0 -36100.0 -0.31 373490.0 -27000.0 -0.23 -0.3795 -0.9896 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O12 mock treatment 476730.0 46500.0 0.4 454560.0 54000.0 0.46 0.604 0.9973 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O13 mock treatment 444270.0 14100.0 0.12 429370.0 28800.0 0.24 0.2576 0.9458 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O14 mock treatment 448800.0 18600.0 0.16 388450.0 -12100.0 -0.1 0.0394 0.2093 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O15 mock treatment 371680.0 -58500.0 -0.5 391170.0 -9350.0 -0.08 -0.4082 -0.8096 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O16 mock treatment 439880.0 9670.0 0.08 366620.0 -33900.0 -0.29 -0.1452 -0.4853 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O17 mock treatment 377920.0 -52300.0 -0.44 378650.0 -21900.0 -0.19 -0.4457 -0.9248 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O18 mock treatment 440810.0 10600.0 0.09 383680.0 -16800.0 -0.14 -0.0372 -0.2204 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O19 mock treatment 384820.0 -45400.0 -0.39 440260.0 39700.0 0.34 -0.0347 -0.0677 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O20 mock treatment 452800.0 22600.0 0.19 418620.0 18100.0 0.15 0.2445 0.9938 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O21 mock treatment 390320.0 -39900.0 -0.34 408850.0 8330.0 0.07 -0.19 -0.5482 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O22 mock treatment 413600.0 -16600.0 -0.14 338790.0 -61700.0 -0.52 -0.4702 -0.8669 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O23 mock treatment 420920.0 -9290.0 -0.08 339520.0 -61000.0 -0.52 -0.4218 -0.8057 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 O24 mock treatment 340640.0 -89600.0 -0.76 372800.0 -27700.0 -0.24 -0.7051 -0.8842 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P01 compound treatment 324600.0 -106000.0 -0.9 337920.0 -62600.0 -0.53 -1.0108 -0.9685 3175838 PK04_130275 NCCCCCNC(=O)[C@H]1C[C@@H]2N([C@H]1c3ccc(O)cc3)C(=O)[C@H](CCCCN)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P02 compound treatment 379120.0 -51100.0 -0.43 350780.0 -49700.0 -0.42 -0.6057 -0.9999 3221398 PK04_130276 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccc(cc3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P03 compound treatment 333760.0 -96400.0 -0.82 357380.0 -43100.0 -0.37 -0.839 -0.9338 3052740 PK04_130277 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3cccc(OCCO)c3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P04 compound treatment 295710.0 -134000.0 -1.14 254130.0 -146000.0 -1.24 -1.6872 -0.9992 3221399 PK04_130278 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(NC(=O)C)c3)c4ccccc42)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P05 compound treatment 284160.0 -146000.0 -1.24 284160.0 -116000.0 -0.99 -1.5765 -0.9935 3176784 PK04_130279 C[N+](C)(C)CCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)OCCOc4ccc(cc4)[C@H]5N6[C@@H]([C@@H](C(=O)OCC=C)[C@]57C(=O)Nc8ccccc87)C(=O)O[C@@H]([C@@H]6c9ccccc9)c%10ccccc%10 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P06 compound treatment 336490.0 -93700.0 -0.8 363790.0 -36700.0 -0.31 -0.7841 -0.916 3221400 PK04_130280 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5C(=O)c6ccccc6Oc7ccccc57)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P07 compound treatment 352560.0 -77600.0 -0.66 333930.0 -66600.0 -0.56 -0.8665 -0.997 3052752 PK04_130281 CC(=O)NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P08 compound treatment 324800.0 -105000.0 -0.9 354050.0 -46500.0 -0.39 -0.9128 -0.9319 3221401 PK04_130282 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3ccccc3)c4ccc(cc42)N5CCC5=O)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P09 compound treatment 228500.0 -202000.0 -1.72 308320.0 -92200.0 -0.78 -1.7664 -0.9367 3052788 PK04_130283 CC(C)C[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)NCCCC[N+](C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P10 compound treatment 277540.0 -153000.0 -1.3 281400.0 -119000.0 -1.01 -1.6329 -0.9923 3221402 PK04_130284 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P11 mock treatment 316600.0 -114000.0 -0.97 246150.0 -154000.0 -1.31 -1.6094 -0.9888 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P12 mock treatment 270850.0 -159000.0 -1.36 304160.0 -96400.0 -0.82 -1.5366 -0.9707 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P13 compound treatment 295090.0 -135000.0 -1.15 294360.0 -106000.0 -0.9 -1.4496 -0.9927 3052846 PK04_130285 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)CNC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P14 compound treatment 209200.0 -221000.0 -1.88 176230.0 -224000.0 -1.9 -2.6748 -1.0 3221404 PK04_130286 C[C@H](O)C(=O)Nc1cccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P15 compound treatment 319260.0 -111000.0 -0.94 173140.0 -227000.0 -1.93 -2.0313 -0.9459 3052836 PK04_130287 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@@H]4CCCN4C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P16 compound treatment 254660.0 -176000.0 -1.49 217350.0 -183000.0 -1.55 -2.1547 -0.9998 3221406 PK04_130288 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4CCCCC4=O)c5ccccc52)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P17 compound treatment 288640.0 -142000.0 -1.2 268540.0 -132000.0 -1.12 -1.6433 -0.9993 3176730 PK04_130289 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P18 compound treatment 186010.0 -244000.0 -2.08 178090.0 -222000.0 -1.89 -2.8032 -0.9988 3221407 PK04_130290 C[C@H](O)C(=O)Nc1ccc(CN2C(=O)[C@]3(O[C@H](CCO)[C@H]([C@@H]3C)[Si](C)(C)F)c4ccccc24)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P19 compound treatment 284960.0 -145000.0 -1.24 264390.0 -136000.0 -1.15 -1.6903 -0.9994 3052799 PK04_130291 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P20 compound treatment 114730.0 -315000.0 -2.68 137890.0 -263000.0 -2.23 -3.4731 -0.9957 3221408 PK04_130292 COc1ccc(cc1)C(=O)Nc2ccc(CN3C(=O)[C@]4(O[C@H](CCO)[C@H]([C@@H]4C)[Si](C)(C)F)c5ccccc35)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P21 compound treatment 234330.0 -196000.0 -1.67 246910.0 -154000.0 -1.3 -2.0997 -0.9926 3176730 PK04_130293 C[N+](C)(C)CCCCNC(=O)[C@@H]1C[C@H]2N([C@@H]1c3ccc(O)cc3)C(=O)[C@H](CCCC[N+](C)(C)C)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P22 compound treatment 166110.0 -264000.0 -2.25 131160.0 -269000.0 -2.28 -3.2044 -1.0 3221410 PK04_130294 C[C@@H]1[C@H]([C@H](CCO)O[C@@]12C(=O)N(CC=C)c3ccc(cc32)N4CCC4=O)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P23 compound treatment 176850.0 -253000.0 -2.16 218260.0 -182000.0 -1.55 -2.6173 -0.9867 3176786 PK04_130295 NCCCC[C@@H]1NC(=O)[C@H]2C[C@H]([C@H](N2C1=O)c3ccc(O)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2130 P24 compound treatment 169090.0 -261000.0 -2.22 156720.0 -244000.0 -2.07 -3.0331 -0.9994 3221411 PK04_130296 C[C@H]1[C@@H]([C@@H](CCO)O[C@]12C(=O)N(Cc3cccc(c3)N4C(=O)COc5ccccc45)c6ccccc62)[Si](C)(C)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A01 compound treatment 100240.0 -257000.0 -2.19 263910.0 -46800.0 -0.4 -1.8264 -0.822 3561840 PK04_181001 CC(C)(C)N(CC=C)C(=O)C1N(Cc2ccccc2)C(=O)C3C(C4OC13C=C4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A02 compound treatment 269640.0 -87600.0 -0.75 226800.0 -83900.0 -0.71 -1.03 -0.9997 3561841 PK04_181002 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A03 compound treatment 164280.0 -193000.0 -1.64 172070.0 -139000.0 -1.18 -1.9921 -0.9866 3561843 PK04_181003 OC1CCC(CC1)N2C(C(=O)N(CC=C)c3ccccc3)C4(OC5C=C4)C(C5C(=O)OCC=C)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A04 compound treatment 227380.0 -130000.0 -1.1 125650.0 -185000.0 -1.57 -1.8909 -0.9852 2065615 PK04_181004 COc1ccc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A05 compound treatment 351730.0 -5510.0 -0.05 131520.0 -179000.0 -1.52 -1.1077 -0.7286 3561844 PK04_181005 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccco4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A06 compound treatment 225120.0 -132000.0 -1.12 238640.0 -72000.0 -0.61 -1.2268 -0.959 3561845 PK04_181006 CCCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)c5ccccc5Cl)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A07 compound treatment 383130.0 25900.0 0.22 135360.0 -175000.0 -1.49 -0.8958 -0.5959 3561847 PK04_181007 Cc1cccc2OC(CC(=O)c12)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A08 compound treatment 291270.0 -66000.0 -0.56 298020.0 -12600.0 -0.11 -0.4727 -0.8273 3561848 PK04_181008 CCCCCN1C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C1=O)c5ccccc5Cl)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A09 compound treatment 139000.0 -218000.0 -1.86 128440.0 -182000.0 -1.55 -2.4059 -0.9959 3561850 PK04_181009 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A10 compound treatment 217630.0 -140000.0 -1.19 263080.0 -47600.0 -0.4 -1.1253 -0.897 3561851 PK04_181010 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A11 compound treatment 192960.0 -164000.0 -1.4 162030.0 -149000.0 -1.26 -1.8798 -0.9987 3561853 PK04_181011 Brc1ccc(CN(C(C(=O)NCc2ccccc2)c3ccco3)C(=O)Cc4ccccc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A12 compound treatment 304800.0 -52400.0 -0.45 278610.0 -32100.0 -0.27 -0.5077 -0.9718 3561854 PK04_181012 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A13 mock treatment 215280.0 -142000.0 -1.21 203810.0 -107000.0 -0.91 -1.4949 -0.99 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A14 mock treatment 440020.0 82800.0 0.7 219260.0 -91400.0 -0.78 -0.0503 -0.048 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A15 compound treatment 209340.0 -148000.0 -1.26 331420.0 20800.0 0.18 -0.7652 -0.6023 3561850 PK04_181013 O=C(Cc1ccccc1)N(Cc2ccccc2)C(C(=O)NCc3ccccc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A16 compound treatment 413190.0 56000.0 0.48 375090.0 64400.0 0.55 0.723 0.9976 3561856 PK04_181014 C[C@H](C(OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@H](CN(CC=C)Cc4ccccc4)N(C(=O)[C@@H]13)C(C)(C)C)c5ccccc5)N(C)C(=O)CCC=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A17 compound treatment 423040.0 65800.0 0.56 360050.0 49400.0 0.42 0.692 0.9898 3561858 PK04_181015 COc1ccc(CNC(=O)OCC2c3ccccc3-c4ccccc24)cc1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A18 compound treatment 268350.0 -88900.0 -0.76 221090.0 -89600.0 -0.76 -1.072 -1.0 3561856 PK04_181016 C[C@H](C(OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@H](CN(CC=C)Cc4ccccc4)N(C(=O)[C@@H]13)C(C)(C)C)c5ccccc5)N(C)C(=O)CCC=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A19 compound treatment 413070.0 55800.0 0.47 387170.0 76500.0 0.65 0.7947 0.9882 3561859 PK04_181017 CCOC(=O)C1C2OC3(C=C2)C(N(Cc4cc(OC)cc(OC)c4)C(=O)C13)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A20 compound treatment 330880.0 -26400.0 -0.22 242650.0 -68000.0 -0.58 -0.5665 -0.9152 3561860 PK04_181018 COc1ccc(CN2[C@H](C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)[C@@H]([C@H]5C(=O)O)C2=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A21 compound treatment 131040.0 -226000.0 -1.92 75540.0 -235000.0 -1.99 -2.771 -0.9998 3561861 PK04_181019 CCOC(=O)C1C2OC3(C=C2)C(N(Cc4ccccc4)C(=O)C13)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A22 compound treatment 433980.0 76700.0 0.65 324280.0 13600.0 0.12 0.5433 0.8195 3561862 PK04_181020 COc1cc(CN2[C@H](C(=O)N(CC=C)Cc3ccccc3)C4(OC5C=C4)[C@@H]([C@H]5C(=O)O)C2=O)ccc1O[SiH](C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A23 compound treatment 349760.0 -7480.0 -0.06 378340.0 67700.0 0.57 0.3609 0.6249 3561864 PK04_181021 O=C(Cc1ccccc1)OC(C(=O)NCc2ccccc2)c3ccco3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 A24 compound treatment 330310.0 -26900.0 -0.23 172000.0 -139000.0 -1.18 -0.9937 -0.8292 3561865 PK04_181022 COc1cc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)ccc1O[SiH](C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B01 compound treatment 390530.0 33300.0 0.28 410910.0 100000.0 0.85 0.8015 0.8943 3561867 PK04_181023 OC(CC=C)c1cccc(c1)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B02 compound treatment 444320.0 87100.0 0.74 402790.0 92100.0 0.78 1.0764 0.9996 1008566 PK04_181024 Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B03 compound treatment 195200.0 -162000.0 -1.38 169470.0 -141000.0 -1.2 -1.8217 -0.9975 3561868 PK04_181025 CC(C)(C)OC(=O)OC(CC=C)c1ccc(cc1)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B04 compound treatment 386260.0 29000.0 0.25 320640.0 9970.0 0.08 0.2344 0.8981 3561869 PK04_181026 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)[Se]c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B05 compound treatment 279050.0 -78200.0 -0.67 376230.0 65600.0 0.56 -0.0771 -0.0889 3561870 PK04_181027 OC(CC1CO1)c2ccc(cc2)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B06 compound treatment 374350.0 17100.0 0.15 156100.0 -155000.0 -1.31 -0.8242 -0.6248 3561871 PK04_181028 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B07 compound treatment 396050.0 38800.0 0.33 306360.0 -4310.0 -0.04 0.2076 0.625 3561872 PK04_181029 OC(CSc1nc(c(o1)c2ccccc2)c3ccccc3)CC(O)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B08 compound treatment 246350.0 -111000.0 -0.94 189370.0 -121000.0 -1.03 -1.3946 -0.9991 3561873 PK04_181030 CC(C)CC1CC(=O)C=C(Cl)N1C(=O)OC(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B09 compound treatment 450720.0 93500.0 0.8 326900.0 16200.0 0.14 0.6597 0.8174 3561874 PK04_181031 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B10 compound treatment 439390.0 82200.0 0.7 346440.0 35800.0 0.3 0.7088 0.9302 3561875 PK04_181032 COC(=O)C1=C(Cl)N(C(CC(C)C)CC1=O)C(=O)OC(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B11 compound treatment 473020.0 116000.0 0.98 368500.0 57800.0 0.49 1.0434 0.9482 3561876 PK04_181033 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B12 compound treatment 213500.0 -144000.0 -1.22 170990.0 -140000.0 -1.18 -1.7025 -0.9999 3561877 PK04_181034 COC(=O)C1=C(OC)N(C(CC(C)C)CC1=O)C(=O)OC(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B13 mock treatment 320560.0 -36700.0 -0.31 349380.0 38700.0 0.33 0.0116 0.0255 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B14 mock treatment 468970.0 112000.0 0.95 152080.0 -159000.0 -1.35 -0.2791 -0.1694 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B15 compound treatment 177130.0 -180000.0 -1.53 254880.0 -55800.0 -0.47 -1.4181 -0.8843 3561878 PK04_181035 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2CC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)OC(O2)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B16 compound treatment 4610.0 -353000.0 -3.0 4040.0 -307000.0 -2.6 -3.9605 -0.9975 3561879 PK04_181036 CC(C)CC1CC(=O)C(=C(Cl)N1C(=O)OC(C)(C)C)I 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B17 compound treatment 373690.0 16500.0 0.14 230880.0 -79800.0 -0.68 -0.3796 -0.5493 3561880 PK04_181037 OC(CC1CO1)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B18 compound treatment 459360.0 102000.0 0.87 353130.0 42500.0 0.36 0.869 0.924 3561881 PK04_181038 CC(C)(C)OC(=O)NCC=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B19 compound treatment 418030.0 60800.0 0.52 229050.0 -81600.0 -0.69 -0.1239 -0.1433 3561882 PK04_181039 CN(CC(O)CC(O)c1ccccc1)Cc2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B20 compound treatment 409330.0 52100.0 0.44 235520.0 -75100.0 -0.64 -0.1374 -0.177 3561883 PK04_181040 COc1ccc(CN(C(=C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B21 compound treatment 457120.0 99900.0 0.85 378810.0 68100.0 0.58 1.0096 0.9824 3561884 PK04_181041 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccc(cc6)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B22 compound treatment 6080.0 -351000.0 -2.99 5320.0 -305000.0 -2.59 -3.9439 -0.9975 3561885 PK04_181042 COc1ccc(CNS(=O)(=O)c2ccc(cc2[N+](=O)[O-])[N+](=O)[O-])c(OC)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B23 compound treatment 472360.0 115000.0 0.98 419100.0 108000.0 0.92 1.3429 0.9995 3561886 PK04_181043 OC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccncc3)CC(O2)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 B24 compound treatment 58640.0 -299000.0 -2.54 26650.0 -284000.0 -2.41 -3.4998 -0.9996 3561887 PK04_181044 Brc1ccc(cc1)S(=O)(=O)N2C[C@H]2C=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C01 compound treatment 383810.0 26600.0 0.23 368800.0 58100.0 0.49 0.5085 0.9374 3561889 PK04_181045 O=C(Cc1ccccc1)N2CC(=O)Oc3ccccc23 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C02 compound treatment 403680.0 46400.0 0.4 359580.0 48900.0 0.41 0.5728 0.9997 3561890 PK04_181046 CCCCCNC(=O)[C@H]1N(C(=O)[C@@H]2[C@H](C3OC12C=C3)C(=O)OCC)c4ccccc4Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C03 compound treatment 344700.0 -12500.0 -0.11 359200.0 48500.0 0.41 0.2157 0.5072 3561892 PK04_181047 CCOC(=O)C1C2OC3(C=C2)C(N(CCCCCCO)C(=O)C13)C(=O)N(CC=C)Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C04 compound treatment 421950.0 64700.0 0.55 350170.0 39500.0 0.34 0.6262 0.9717 2065568 PK04_181048 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C05 compound treatment 98780.0 -258000.0 -2.2 21670.0 -289000.0 -2.45 -3.2882 -0.9985 3561893 PK04_181049 OCCCCCCN1C(C(=O)N(CC=C)Cc2ccccc2)C3(OC4C=C3)C(C4C(=O)OCC=C)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C06 compound treatment 393140.0 35900.0 0.31 341400.0 30700.0 0.26 0.4003 0.9969 2065566 PK04_181050 CCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C07 compound treatment 377010.0 19800.0 0.17 328350.0 17700.0 0.15 0.225 0.9984 3561894 PK04_181051 CCOC(=O)C1C2OC3(C=C2)C(N(C4CCC(O)CC4)C(=O)C13)C(=O)N(CC=C)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C08 compound treatment 382470.0 25200.0 0.21 306490.0 -4180.0 -0.04 0.1267 0.5825 2065605 PK04_181052 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C09 compound treatment 357850.0 612.0 0.01 282190.0 -28500.0 -0.24 -0.1671 -0.6917 3561895 PK04_181053 O=C(Cc1ccccc1)OC(COCc2ccccc2)C(=O)NCc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C10 compound treatment 321540.0 -35700.0 -0.3 286850.0 -23800.0 -0.2 -0.3576 -0.9804 2065603 PK04_181054 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3cccs3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C11 mock treatment 415050.0 57800.0 0.49 335360.0 24700.0 0.21 0.4959 0.9276 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C12 mock treatment 373130.0 15900.0 0.14 304020.0 -6650.0 -0.06 0.0557 0.3804 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C13 compound treatment 447260.0 90000.0 0.77 273470.0 -37200.0 -0.32 0.3184 0.3844 3561896 PK04_181055 CCOC(=O)C1C2OC3(C=C2)C(N(C4CCC(O)CC4)C(=O)C13)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C14 compound treatment 412410.0 55200.0 0.47 305440.0 -5230.0 -0.04 0.3005 0.6375 2065601 PK04_181056 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C15 mock treatment 346930.0 -10300.0 -0.09 299540.0 -11100.0 -0.09 -0.1288 -0.9993 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C16 mock treatment 396640.0 39400.0 0.34 211060.0 -99600.0 -0.84 -0.3604 -0.3965 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C17 compound treatment 167380.0 -190000.0 -1.62 148170.0 -162000.0 -1.38 -2.1168 -0.9969 3561897 PK04_181057 OC1CCC(CC1)N2C(C(=O)NCc3ccccc3)C4(OC5C=C4)C(C5C(=O)OCC=C)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C18 compound treatment 193560.0 -164000.0 -1.39 108510.0 -202000.0 -1.71 -2.1972 -0.9947 3057099 PK04_181058 O=C(NCc1ccccc1)C(OC(=O)c2ccccc2)c3ccco3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C19 compound treatment 272560.0 -84700.0 -0.72 275470.0 -35200.0 -0.3 -0.7205 -0.924 3561892 PK04_181059 CCOC(=O)C1C2OC3(C=C2)C(N(CCCCCCO)C(=O)C13)C(=O)N(CC=C)Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C20 compound treatment 353970.0 -3270.0 -0.03 310790.0 123.0 0.0 -0.0189 -0.6802 3057100 PK04_181060 COc1ccc(NC(=O)C(OC(=O)c2ccccc2)c3ccco3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C21 compound treatment 327080.0 -30200.0 -0.26 318240.0 7570.0 0.06 -0.136 -0.5142 3561898 PK04_181061 CC(CO)N1[C@@H]2C(=O)N(Cc3ccccc3)CC=C[C@]42O[C@@H]5/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]4C1=O)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C22 compound treatment 395170.0 37900.0 0.32 333250.0 22600.0 0.19 0.3636 0.969 3176076 PK04_181062 CC(C)(C)NC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C23 compound treatment 439790.0 82600.0 0.7 314250.0 3580.0 0.03 0.5181 0.737 3561899 PK04_181063 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 C24 compound treatment 345480.0 -11800.0 -0.1 353310.0 42600.0 0.36 0.185 0.4931 2065566 PK04_181064 CCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D01 compound treatment 394340.0 37100.0 0.32 374650.0 64000.0 0.54 0.607 0.9667 3561900 PK04_181065 COCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D02 compound treatment 436110.0 78900.0 0.67 365660.0 55000.0 0.47 0.8043 0.9842 3561901 PK04_181066 COc1cc(OC)c(CNS(=O)(=O)c2ccc(Br)cc2)c(OC)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D03 compound treatment 307590.0 -49600.0 -0.42 326400.0 15700.0 0.13 -0.2043 -0.4612 3561902 PK04_181067 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D04 compound treatment 417550.0 60300.0 0.51 339910.0 29200.0 0.25 0.5382 0.9444 3561903 PK04_181068 COc1ccc(CN(C(COC(=O)c2cccc(OC)c2O)C=C)S(=O)(=O)c3ccc(Br)cc3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D05 compound treatment 215520.0 -142000.0 -1.21 154630.0 -156000.0 -1.32 -1.7885 -0.9989 3215593 PK04_181069 OCCSCC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)NO)cc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D06 compound treatment 345990.0 -11200.0 -0.1 387570.0 76900.0 0.65 0.3936 0.597 3561904 PK04_181070 COC(=O)C1CC=C(CC1C(=O)OC)N(Cc2ccc(OC)cc2)S(=O)(=O)c3ccc(Br)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D07 compound treatment 437730.0 80500.0 0.68 277550.0 -33100.0 -0.28 0.2856 0.3858 3561905 PK04_181071 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CN(C)Cc3ccccc3)CC(O2)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D08 compound treatment 356740.0 -498.0 0.0 339840.0 29200.0 0.25 0.172 0.6949 3561906 PK04_181072 COc1ccc(CN([C@H](COC(=O)c2ccc(cc2)[N+](=O)[O-])C=C)S(=O)(=O)c3ccc(Br)cc3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D09 compound treatment 364810.0 7570.0 0.06 291930.0 -18700.0 -0.16 -0.0668 -0.3897 3561908 PK04_181073 OC(CSc1nc2ccccc2o1)CC(O)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D10 compound treatment 420050.0 62800.0 0.53 157490.0 -153000.0 -1.3 -0.5409 -0.385 3561909 PK04_181074 Brc1ccc(cc1)N2C(CN(C2=O)S(=O)(=O)c3ccc(Br)cc3)C=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D11 mock treatment 465930.0 109000.0 0.92 379260.0 68600.0 0.58 1.0653 0.9751 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D12 mock treatment 375750.0 18500.0 0.16 310720.0 52.7 0.0 0.1117 0.7091 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D13 compound treatment 420840.0 63600.0 0.54 332930.0 22300.0 0.19 0.5161 0.9006 3561910 PK04_181075 COC(=O)CCCCCCC(=O)NOCc1ccccc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D14 compound treatment 433730.0 76500.0 0.65 200820.0 -110000.0 -0.93 -0.1987 -0.1749 3561911 PK04_181076 COc1ccc(CN([C@H](CI)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D15 mock treatment 376920.0 19700.0 0.17 377370.0 66700.0 0.57 0.5185 0.8787 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D16 mock treatment 451300.0 94100.0 0.8 411730.0 101000.0 0.86 1.172 0.9994 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D17 compound treatment 404830.0 47600.0 0.4 281120.0 -29500.0 -0.25 0.1091 0.229 3561913 PK04_181077 OC(=O)CCCCCCC(=O)NOCc1ccccc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D18 compound treatment 247360.0 -110000.0 -0.93 171170.0 -139000.0 -1.18 -1.4977 -0.9932 3561914 PK04_181078 COc1ccc(CN(C2=CCC3C(C2)C(=O)N(C)C3=O)S(=O)(=O)c4ccc(Br)cc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D19 compound treatment 401380.0 44100.0 0.38 372700.0 62000.0 0.53 0.6376 0.9863 3561915 PK04_181079 OCc1ccc(NC(=O)CCCCCCC(=O)NOCc2ccccc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D20 compound treatment 248900.0 -108000.0 -0.92 172260.0 -138000.0 -1.17 -1.4819 -0.9928 3561916 PK04_181080 COCCCN(CC(O)CO)C[C@]1(O)CCC2[C@]1(C)CCC3[C@@]4(C)CC[C@H](O)C[C@@]54C=C[C@]23C(=C5)C(=O)c6ccc(OC)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D21 compound treatment 382450.0 25200.0 0.21 305440.0 -5230.0 -0.04 0.1203 0.5493 3561917 PK04_181081 O=Cc1ccc(NC(=O)CCCCCCC(=O)NOCc2ccccc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D22 compound treatment 326720.0 -30500.0 -0.26 376080.0 65400.0 0.55 0.2088 0.3408 3561918 PK04_181082 COCCCN(CC(O)CO)C[C@]1(O)CCC2C3=CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@@]21C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D23 compound treatment 361960.0 4720.0 0.04 183070.0 -128000.0 -1.08 -0.7369 -0.6804 3561919 PK04_181083 OC(CN=[N+]=[N-])CC(O)c1ccccc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 D24 compound treatment 370100.0 12900.0 0.11 319860.0 9190.0 0.08 0.1325 0.9862 3561920 PK04_181084 COCCCN(C[C@]1(O)CCC2C3=CC=C4C[C@@H](O)CC[C@]4(C)C3CC[C@@]21C)C(=O)O[C@H]5C[C@@H](C)CC[C@@H]5C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E01 mock treatment 434840.0 77600.0 0.66 241710.0 -69000.0 -0.58 0.0532 0.0603 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E02 mock treatment 475120.0 118000.0 1.0 413720.0 103000.0 0.87 1.3273 0.9977 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E03 compound treatment 459200.0 102000.0 0.87 375410.0 64700.0 0.55 1.0017 0.9757 3561899 PK04_181085 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E04 compound treatment 434890.0 77700.0 0.66 215570.0 -95100.0 -0.81 -0.1033 -0.0991 2065568 PK04_181086 CCCCCNC(=O)C(OC(=O)c1ccccc1)c2ccco2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E05 compound treatment 410450.0 53200.0 0.45 356440.0 45800.0 0.39 0.5947 0.9971 3561899 PK04_181087 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E06 compound treatment 404350.0 47100.0 0.4 268760.0 -41900.0 -0.36 0.032 0.0598 2065570 PK04_181088 O=C(NCc1ccccc1)C(COCc2ccccc2)OC(=O)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E07 compound treatment 390960.0 33700.0 0.29 240540.0 -70100.0 -0.59 -0.2178 -0.3298 3561899 PK04_181089 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E08 compound treatment 365780.0 8540.0 0.07 292380.0 -18300.0 -0.16 -0.0583 -0.3404 2065572 PK04_181090 COc1ccc(NC(=O)C(COCc2ccccc2)OC(=O)c3ccccc3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E09 mock treatment 301610.0 -55600.0 -0.47 400450.0 89800.0 0.76 0.2039 0.2274 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E10 mock treatment 266400.0 -90800.0 -0.77 223710.0 -87000.0 -0.74 -1.068 -0.9997 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E11 compound treatment 301180.0 -56100.0 -0.48 277040.0 -33600.0 -0.29 -0.5389 -0.9698 3561921 PK04_181091 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E12 compound treatment 402650.0 45400.0 0.39 345360.0 34700.0 0.29 0.4813 0.991 2065574 PK04_181092 CC(C)(C)NC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E13 compound treatment 337300.0 -19900.0 -0.17 292040.0 -18600.0 -0.16 -0.2317 -0.9994 3561922 PK04_181093 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(Cc4ccc(OC)cc4)C(=O)[C@@H]13)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E14 compound treatment 442690.0 85500.0 0.73 335970.0 25300.0 0.21 0.6658 0.8784 2065576 PK04_181094 CCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E15 compound treatment 254610.0 -103000.0 -0.87 349920.0 39300.0 0.33 -0.3819 -0.4087 3561841 PK04_181095 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E16 compound treatment 365850.0 8610.0 0.07 364000.0 53300.0 0.45 0.3717 0.8111 2065599 PK04_181096 CCCCCNC(=O)C(COCc1ccccc1)OC(=O)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E17 mock treatment 406520.0 49300.0 0.42 355920.0 45300.0 0.38 0.5679 0.999 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E18 mock treatment 223750.0 -133000.0 -1.14 370150.0 59500.0 0.5 -0.4462 -0.3591 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E19 compound treatment 291110.0 -66100.0 -0.56 331370.0 20700.0 0.18 -0.2736 -0.4643 3561841 PK04_181097 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E20 compound treatment 427760.0 70500.0 0.6 367850.0 57200.0 0.49 0.7672 0.9944 3561923 PK04_181098 CCCNC(=O)COc1ccc(C=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E21 compound treatment 300480.0 -56800.0 -0.48 211870.0 -98800.0 -0.84 -0.934 -0.9657 3561841 PK04_181099 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E22 compound treatment 392110.0 34900.0 0.3 402990.0 92300.0 0.78 0.7635 0.9117 3561924 PK04_181100 CCCNC(=O)Cc1ccc(N)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E23 compound treatment 383000.0 25800.0 0.22 350830.0 40200.0 0.34 0.3959 0.9772 3561841 PK04_181101 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 E24 compound treatment 429440.0 72200.0 0.61 336710.0 26000.0 0.22 0.5905 0.9047 3561925 PK04_181102 CCOC(=O)/C=C/c1ccccc1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F01 mock treatment 324420.0 -32800.0 -0.28 446110.0 135000.0 1.15 0.615 0.5201 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F02 mock treatment 294880.0 -62400.0 -0.53 193320.0 -117000.0 -1.0 -1.079 -0.9566 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F03 compound treatment 349890.0 -7350.0 -0.06 279370.0 -31300.0 -0.27 -0.2319 -0.8503 3561927 PK04_181103 OC(CSc1nc(c(o1)c2ccccc2)c3ccccc3)CC(O)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F04 compound treatment 294530.0 -62700.0 -0.53 227600.0 -83100.0 -0.7 -0.8755 -0.9906 1366116 PK04_181104 Brc1ccc2ncnc(NCC=C)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F05 compound treatment 454300.0 97100.0 0.83 382420.0 71800.0 0.61 1.0143 0.9887 3561928 PK04_181105 CN(CC1CC(OC(O1)c2ccc(NC(=O)CCCCCCC(=O)O)cc2)c3ccccc3)Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F06 compound treatment 316700.0 -40500.0 -0.34 249680.0 -61000.0 -0.52 -0.6097 -0.9806 1945167 PK04_181106 C/C(=C/C(=O)c1ccc(Cl)cc1)/Nc2cccc(O)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F07 compound treatment 326510.0 -30700.0 -0.26 372990.0 62300.0 0.53 0.189 0.3204 3561929 PK04_181107 OC(CSc1nc2ccccc2s1)CC(O)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F08 compound treatment 382880.0 25600.0 0.22 386340.0 75700.0 0.64 0.6082 0.897 1448632 PK04_181108 Nn1cnc2-c3ccccc3CC4(CCCC4)c2c1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F09 mock treatment 322100.0 -35100.0 -0.3 343780.0 33100.0 0.28 -0.0128 -0.0311 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F10 mock treatment 356800.0 -438.0 0.0 375200.0 64500.0 0.55 0.3844 0.7023 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F11 compound treatment 266840.0 -90400.0 -0.77 343900.0 33200.0 0.28 -0.3445 -0.4205 3561930 PK04_181109 OC(CSc1ccccn1)CC(O)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F12 compound treatment 293760.0 -63500.0 -0.54 324480.0 13800.0 0.12 -0.299 -0.5411 3561931 PK04_181110 [O-][N+](=O)c1ccccc1/C=C/c2ccncc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F13 compound treatment 189320.0 -168000.0 -1.43 162580.0 -148000.0 -1.26 -1.8984 -0.9979 3561933 PK04_181111 ONC(=O)CCCCCCC(=O)NOCc1ccccc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F14 compound treatment 388820.0 31600.0 0.27 210400.0 -100000.0 -0.85 -0.4114 -0.4613 1679359 PK04_181112 OC(=O)CCCN1C(=O)CSC1=S 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F15 compound treatment 420420.0 63200.0 0.54 331120.0 20500.0 0.17 0.5028 0.8901 1020755 PK04_181113 O=C(C[n+]1ccc2ccccc2c1)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F16 compound treatment 455640.0 98400.0 0.84 369050.0 58400.0 0.5 0.9421 0.9686 3561934 PK04_181114 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)O)C2=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F17 mock treatment 375140.0 17900.0 0.15 358140.0 47500.0 0.4 0.3924 0.9115 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F18 mock treatment 225670.0 -132000.0 -1.12 217250.0 -93400.0 -0.79 -1.3518 -0.9857 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F19 compound treatment 157030.0 -200000.0 -1.7 243930.0 -66700.0 -0.57 -1.6047 -0.894 3561936 PK04_181115 Brc1c2OCOc2ccc1C[n+]3ccc4ccccc4c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F20 compound treatment 104760.0 -252000.0 -2.15 82000.0 -229000.0 -1.94 -2.8904 -0.9987 3561937 PK04_181116 COc1ccc(cc1)S(=O)(=O)Nc2ccccc2/C=C/c3ccncc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F21 compound treatment 409760.0 52500.0 0.45 339460.0 28800.0 0.24 0.4887 0.9596 3561939 PK04_181117 CC(C)(C)[Si](C)(C)Oc1ccc2cc[n+](Cc3ccccc3Br)cc2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F22 compound treatment 342810.0 -14400.0 -0.12 240040.0 -70600.0 -0.6 -0.5104 -0.8346 1936946 PK04_181118 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F23 compound treatment 235720.0 -122000.0 -1.03 194790.0 -116000.0 -0.98 -1.4261 -0.9997 3561940 PK04_181119 COc1ccc(Br)c(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 F24 compound treatment 422560.0 65300.0 0.56 356130.0 45500.0 0.39 0.6656 0.9841 3561941 PK04_181120 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)O)C2=O)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G01 compound treatment 414840.0 57600.0 0.49 427540.0 117000.0 0.99 1.0475 0.9472 3561841 PK04_181121 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G02 compound treatment 464240.0 107000.0 0.91 387680.0 77000.0 0.65 1.1056 0.9868 3561943 PK04_181122 O=C1CSC(N1c2ccc(cc2)c3ccccc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G03 mock treatment 347750.0 -9490.0 -0.08 328730.0 18100.0 0.15 0.0513 0.296 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G04 mock treatment 369060.0 11800.0 0.1 305410.0 -5260.0 -0.04 0.0396 0.3598 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G05 compound treatment 293680.0 -63600.0 -0.54 289720.0 -20900.0 -0.18 -0.508 -0.8925 PK04_181123 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G06 compound treatment 252110.0 -105000.0 -0.89 353330.0 42700.0 0.36 -0.3765 -0.3902 3561944 PK04_181124 CC(C)(C)c1ccc(cc1)N2C(SCC2=O)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G07 compound treatment 389830.0 32600.0 0.28 157160.0 -154000.0 -1.3 -0.7247 -0.5443 PK04_181125 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G08 compound treatment 429160.0 71900.0 0.61 354360.0 43700.0 0.37 0.6947 0.9712 3561945 PK04_181126 CCOC(=O)/C=C(\C)/c1ccccc1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G09 compound treatment 382490.0 25300.0 0.21 332340.0 21700.0 0.18 0.2819 0.997 3561841 PK04_181127 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G10 compound treatment 437990.0 80800.0 0.69 345140.0 34500.0 0.29 0.6925 0.9276 3561947 PK04_181128 CCOC(=O)/C=C/c1c(OC)cccc1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G11 compound treatment 347010.0 -10200.0 -0.09 250240.0 -60400.0 -0.51 -0.424 -0.8155 3561899 PK04_181129 CC(CO)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G12 compound treatment 364050.0 6810.0 0.06 273950.0 -36700.0 -0.31 -0.1793 -0.5658 3561949 PK04_181130 CCCNC(=O)Cc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G13 compound treatment 401450.0 44200.0 0.38 335380.0 24700.0 0.21 0.4142 0.9619 3561950 PK04_181131 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)c6cccc(Cl)c6CO)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G14 compound treatment 382140.0 24900.0 0.21 317600.0 6930.0 0.06 0.1914 0.8705 3561952 PK04_181132 COc1cc(/C=C/CO)cc(OC)c1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G15 compound treatment 284570.0 -72700.0 -0.62 257920.0 -52700.0 -0.45 -0.7535 -0.9874 3561841 PK04_181133 COc1ccc(CN2[C@@H]3C(=O)N(Cc4ccccc4)CC=C[C@]53O[C@@H]6/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]6[C@H]5C2=O)c7ccccc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G16 compound treatment 406750.0 49500.0 0.42 346840.0 36200.0 0.31 0.5148 0.9879 3561954 PK04_181134 COc1ccccc1/C=C/CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G17 compound treatment 368050.0 10800.0 0.09 365510.0 54800.0 0.47 0.394 0.8308 3561956 PK04_181135 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4cccc(Cl)c4CO)C(=O)N(CC=C)Cc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G18 compound treatment 312720.0 -44500.0 -0.38 239370.0 -71300.0 -0.6 -0.6955 -0.9746 3561958 PK04_181136 O=C1CS(=O)(=O)C(N1c2ccc(cc2)c3ccccc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G19 mock treatment 230880.0 -126000.0 -1.07 231000.0 -79700.0 -0.68 -1.238 -0.975 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G20 mock treatment 405130.0 47900.0 0.41 344850.0 34200.0 0.29 0.4931 0.9861 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G21 compound treatment 397280.0 40000.0 0.34 350590.0 39900.0 0.34 0.4803 1.0 3561959 PK04_181137 CC(CO)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O[C@@H]([C@@H](C)N(C)C(=O)CCC=C)c5ccccc5)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G22 compound treatment 376060.0 18800.0 0.16 288000.0 -22700.0 -0.19 -0.0227 -0.0909 3561961 PK04_181138 CC(C)(C)c1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G23 compound treatment 200200.0 -157000.0 -1.34 156040.0 -155000.0 -1.31 -1.8722 -1.0 3561959 PK04_181139 CC(CO)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O[C@@H]([C@@H](C)N(C)C(=O)CCC=C)c5ccccc5)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 G24 compound treatment 431870.0 74600.0 0.63 230280.0 -80400.0 -0.68 -0.0332 -0.0357 2093329 PK04_181140 COC(=O)/C=C/c1cc(OC)c(OC)c(OC)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H01 compound treatment 479040.0 122000.0 1.04 429040.0 118000.0 1.0 1.4427 0.9999 3561962 PK04_181141 Brc1ccccc1C(=O)[n+]2ccc3ccccc3c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H02 compound treatment 474360.0 117000.0 1.0 414970.0 104000.0 0.88 1.3302 0.9982 3561963 PK04_181142 COc1ccccc1/C=C/2\SC(=S)N(CCCC(=O)O)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H03 mock treatment 496000.0 139000.0 1.18 183590.0 -127000.0 -1.08 0.0725 0.0454 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H04 mock treatment 330730.0 -26500.0 -0.23 205980.0 -105000.0 -0.89 -0.7874 -0.8594 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H05 compound treatment 301660.0 -55600.0 -0.47 192130.0 -119000.0 -1.01 -1.0453 -0.9408 3561965 PK04_181143 COc1cc2CC[N+](=Cc2cc1O[Si](C)(C)C(C)(C)C)Cc3ccccc3Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H06 compound treatment 246370.0 -111000.0 -0.94 108280.0 -202000.0 -1.72 -1.8809 -0.9602 3561966 PK04_181144 COc1cccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H07 compound treatment 310420.0 -46800.0 -0.4 389280.0 78600.0 0.67 0.1899 0.2445 3561968 PK04_181145 COc1cc2CC[N+](=Cc2cc1OC)C(=O)c3ccccc3Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H08 compound treatment 306180.0 -51100.0 -0.43 153660.0 -157000.0 -1.33 -1.2489 -0.8915 3561969 PK04_181146 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3C4CC5CC(C4)CC3C5)C2=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H09 compound treatment 147900.0 -209000.0 -1.78 146360.0 -164000.0 -1.39 -2.2448 -0.9926 3561971 PK04_181147 Oc1ccc2CCN(Cc3ccccc3Br)C(C=C)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H10 compound treatment 284680.0 -72600.0 -0.62 217450.0 -93200.0 -0.79 -0.9956 -0.9925 3561972 PK04_181148 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(O)(C4)C3)C5)C2=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H11 compound treatment 309960.0 -47300.0 -0.4 209840.0 -101000.0 -0.86 -0.8892 -0.9408 3561974 PK04_181149 Brc1c[n+](Cc2ccccc2)cc3ccccc13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H12 compound treatment 312900.0 -44300.0 -0.38 213120.0 -97500.0 -0.83 -0.8518 -0.9367 3561975 PK04_181150 COc1ccc(/C=C/2\SC(=S)N(CCCC(=O)NCC3(CC4CC5CC(C4)C3)C5)C2=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H13 compound treatment 139200.0 -218000.0 -1.85 107040.0 -204000.0 -1.73 -2.533 -0.9994 3561977 PK04_181151 COc1ccc(Br)c(C[n+]2cc(Br)c3ccccc3c2)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H14 compound treatment 234640.0 -123000.0 -1.04 124320.0 -186000.0 -1.58 -1.8552 -0.9796 3561978 PK04_181152 COc1ccccc1/C=C/2\SC(=S)N(CCCC(=O)NC3(CC4CC5CC(C4)C3)C5)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H15 compound treatment 410200.0 53000.0 0.45 407280.0 96600.0 0.82 0.8981 0.9603 1003512 PK04_181153 C[n+]1ccc2ccccc2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H16 compound treatment 145400.0 -212000.0 -1.8 193760.0 -117000.0 -0.99 -1.9756 -0.9604 3561980 PK04_181154 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H17 compound treatment 400340.0 43100.0 0.37 353860.0 43200.0 0.37 0.5184 1.0 1032420 PK04_181155 C(c1ccccc1)[n+]2ccc3ccccc3c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H18 compound treatment 307860.0 -49400.0 -0.42 232650.0 -78000.0 -0.66 -0.765 -0.9759 3561982 PK04_181156 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H19 mock treatment 449200.0 92000.0 0.78 314120.0 3450.0 0.03 0.5739 0.7331 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H20 mock treatment 411680.0 54400.0 0.46 367740.0 57100.0 0.48 0.6698 0.9998 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H21 compound treatment 157540.0 -200000.0 -1.7 139470.0 -171000.0 -1.45 -2.2282 -0.997 3561984 PK04_181157 COc1ccc(Br)c(C[n+]2ccc3ccccc3c2)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H22 compound treatment 9630.0 -348000.0 -2.96 10840.0 -300000.0 -2.54 -3.8895 -0.9972 3561985 PK04_181158 O=C1C=C[C@@H]2[C@@H]3C=C[C@H]([C@@H]2[C@]41CO4)[C@@]5(CO5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H23 compound treatment 3280.0 -354000.0 -3.01 2570.0 -308000.0 -2.61 -3.9773 -0.9975 3561987 PK04_181159 COc1ccc(Br)c(C[n+]2ccc3c(cccc3c2)[N+](=O)[O-])c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 H24 compound treatment 220220.0 -137000.0 -1.17 328960.0 18300.0 0.16 -0.7145 -0.6076 3561988 PK04_181160 CC1(C)C[C@H]2C[C@H]3C(=C[C@]2(CO1)C(=O)[C@@]43CO4)Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I01 compound treatment 173970.0 -183000.0 -1.56 212060.0 -98600.0 -0.84 -1.6939 -0.9574 3561956 PK04_181161 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4cccc(Cl)c4CO)C(=O)N(CC=C)Cc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I02 compound treatment 434670.0 77400.0 0.66 419260.0 109000.0 0.92 1.1172 0.9865 3561990 PK04_181162 CCCNC(=O)Cc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I03 compound treatment 436830.0 79600.0 0.68 190800.0 -120000.0 -1.02 -0.2402 -0.1966 3561991 PK04_181163 OCc1c(Cl)cccc1N2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OCC=C)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I04 compound treatment 426170.0 68900.0 0.59 360340.0 49700.0 0.42 0.7126 0.9869 3561993 PK04_181164 COc1ccccc1/C(=C/CO)/C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I05 mock treatment 163160.0 -194000.0 -1.65 251640.0 -59000.0 -0.5 -1.5215 -0.8819 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I06 mock treatment 451580.0 94300.0 0.8 330760.0 20100.0 0.17 0.688 0.8386 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I07 compound treatment 275520.0 -81700.0 -0.7 113770.0 -197000.0 -1.67 -1.6726 -0.9245 3561995 PK04_181165 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I08 compound treatment 436680.0 79400.0 0.68 164820.0 -146000.0 -1.24 -0.3969 -0.2816 3561996 PK04_181166 COc1ccccc1/C(=C/C=O)/C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I09 compound treatment 334740.0 -22500.0 -0.19 330530.0 19900.0 0.17 -0.0162 -0.0635 3561998 PK04_181167 OCc1c(Cl)cccc1N2[C@@H](C(=O)NCc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)O)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I10 compound treatment 140710.0 -217000.0 -1.84 149450.0 -161000.0 -1.37 -2.2695 -0.9892 2069262 PK04_181168 COc1cc(/C=C/C=O)cc(OC)c1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I11 compound treatment 410890.0 53700.0 0.46 312610.0 1940.0 0.02 0.3344 0.7322 3562000 PK04_181169 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)c4ccccc4Cl)C(=O)N(CC=C)Cc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I12 compound treatment 473440.0 116000.0 0.99 396600.0 85900.0 0.73 1.2145 0.9888 3562002 PK04_181170 CCOC(=O)/C=C/c1cccc(c1)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I13 compound treatment 220380.0 -137000.0 -1.16 225440.0 -85200.0 -0.72 -1.3345 -0.9737 3562003 PK04_181171 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3C(=O)N(Cc4ccccc4)[C@@H]5C(=O)N(Cc6ccccc6)CC=C[C@]35O[C@@H]2/C=C/CCC(=O)N1C)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I14 compound treatment 288480.0 -68800.0 -0.58 376120.0 65500.0 0.56 -0.021 -0.0261 3562005 PK04_181172 COc1cccc(OC)c1/C=C/CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I15 compound treatment 282270.0 -75000.0 -0.64 155060.0 -156000.0 -1.32 -1.3843 -0.9443 3562007 PK04_181173 CCCCNC(=O)[C@@H]1N(C2CCCCC2)C(=O)[C@H]3[C@@H]([C@H]4O[C@@]13C=C4)C(=O)OCC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I16 compound treatment 273190.0 -84000.0 -0.72 369680.0 59000.0 0.5 -0.1516 -0.1737 3562009 PK04_181174 Clc1cccc(c1)N2C(SCC2=O)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I17 compound treatment 145440.0 -212000.0 -1.8 222560.0 -88100.0 -0.75 -1.8026 -0.9241 3561995 PK04_181175 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I18 compound treatment 264230.0 -93000.0 -0.79 292320.0 -18300.0 -0.16 -0.6695 -0.8303 3065130 PK04_181176 Clc1ccc(cc1)N2C(SCC2=O)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I19 compound treatment 292210.0 -65000.0 -0.55 181770.0 -129000.0 -1.09 -1.1643 -0.9502 3562010 PK04_181177 C[C@H]([C@H](OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4)c5ccccc5)N(C)C(=O)CCC=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I20 compound treatment 350760.0 -6480.0 -0.06 363950.0 53300.0 0.45 0.2806 0.6163 3562012 PK04_181178 OC/C=C/c1cccc(c1)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I21 mock treatment 390350.0 33100.0 0.28 354930.0 44300.0 0.38 0.4647 0.99 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I22 mock treatment 459000.0 102000.0 0.87 237970.0 -72700.0 -0.62 0.1761 0.1657 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I23 compound treatment 325370.0 -31900.0 -0.27 321170.0 10500.0 0.09 -0.1287 -0.451 3562014 PK04_181179 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3C(=O)N([C@@H]4C(=O)N(Cc5ccccc5)CC=C[C@]34O[C@@H]2/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 I24 compound treatment 230750.0 -126000.0 -1.08 199230.0 -111000.0 -0.95 -1.4293 -0.9979 3215604 PK04_181180 O=C/1N(C(c2ccccc2)S(=O)(=O)\C1=C/c3ccc4ccccc4c3)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J01 compound treatment 404640.0 47400.0 0.4 292850.0 -17800.0 -0.15 0.1783 0.414 3562016 PK04_181181 COc1ccc(Br)c(C[n+]2ccccc2C)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J02 compound treatment 246450.0 -111000.0 -0.94 268200.0 -42500.0 -0.36 -0.9212 -0.913 3562017 PK04_181182 OCCCCCCO[C@H]1C[C@H]2C(=C[C@]1(Br)C(=O)[C@@]32CO3)Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J03 compound treatment 134880.0 -222000.0 -1.89 308440.0 -2230.0 -0.02 -1.351 -0.7141 3562019 PK04_181183 COc1ccc(Br)c(C[n+]2ccc3ccccc3c2C)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J04 compound treatment 141440.0 -216000.0 -1.84 142810.0 -168000.0 -1.42 -2.305 -0.9921 3562020 PK04_181184 OCCCCO[C@H]1C[C@H]2C(=C[C@]1(Br)C(=O)[C@@]32CO3)Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J05 mock treatment 130560.0 -227000.0 -1.93 186970.0 -124000.0 -1.05 -2.1056 -0.9591 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J06 mock treatment 441220.0 84000.0 0.71 114490.0 -196000.0 -1.66 -0.6715 -0.3708 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J07 compound treatment 293160.0 -64100.0 -0.55 250840.0 -59800.0 -0.51 -0.7443 -0.9994 3562022 PK04_181185 Cc1[n+](Cc2ccccc2)ccc3ccccc13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J08 compound treatment 95700.0 -262000.0 -2.22 67520.0 -243000.0 -2.06 -3.0317 -0.9993 3562023 PK04_181186 BrC1=C[C@@]2(Br)[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J09 compound treatment 301970.0 -55300.0 -0.47 231520.0 -79100.0 -0.67 -0.8072 -0.9848 3562025 PK04_181187 COc1ccc(Br)c(C[n+]2cccc3cc(OC)ccc23)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J10 compound treatment 67440.0 -290000.0 -2.47 59960.0 -251000.0 -2.13 -3.2471 -0.9973 3562026 PK04_181188 COc1ccc(cc1OC)[C@H]2C[C@H]3C(=C[C@]2(Br)C(=O)[C@@]43CO4)Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J11 compound treatment 251050.0 -106000.0 -0.9 346880.0 36200.0 0.31 -0.4216 -0.4418 3562028 PK04_181189 COc1ccc(Br)c(C[N+]2=C(C)CCC2)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J12 compound treatment 137960.0 -219000.0 -1.87 202450.0 -108000.0 -0.92 -1.9682 -0.9467 3562029 PK04_181190 COc1ccc(CCNC(=O)[C@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccccc4)c5cc(ccc5F)[N+](=O)[O-])cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J13 compound treatment 250800.0 -106000.0 -0.91 293990.0 -16700.0 -0.14 -0.7403 -0.8078 3562031 PK04_181191 COc1ccc(Br)c(CN2CCc3cc(OC)c(OC)cc3C2C#Cc4ccccc4)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J14 compound treatment 377310.0 20100.0 0.17 310080.0 -587.0 0.0 0.1172 0.6862 3562032 PK04_181192 COc1ccc(CCNC(=O)[C@@]2(CC(=O)N(Cc3ccccc3)[C@@H]2c4ccccc4)c5cc(ccc5F)[N+](=O)[O-])cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J15 compound treatment 204480.0 -153000.0 -1.3 218420.0 -92200.0 -0.78 -1.4722 -0.9705 3562033 PK04_181193 COC(CN(Cc1cccc(OC)c1)S(=O)(=O)c2ccc(C)cc2)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J16 compound treatment 301410.0 -55800.0 -0.47 233330.0 -77300.0 -0.66 -0.7997 -0.9874 3562034 PK04_181194 COc1ccc(CCN2C(=O)C3(CC(=O)N(Cc4ccccc4)C3c5ccccc5)c6cc(ccc26)[N+](=O)[O-])cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J17 compound treatment 248520.0 -109000.0 -0.92 349130.0 38500.0 0.33 -0.4233 -0.4316 3562035 PK04_181195 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J18 compound treatment 369530.0 12300.0 0.1 391700.0 81000.0 0.69 0.56 0.8054 3562036 PK04_181196 C[C@@]1(CCc2ccccc2)C[C@@H](C[Si](C)(C)C(c3ccccc3)c4ccccc4)OO1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J19 compound treatment 164530.0 -193000.0 -1.64 200480.0 -110000.0 -0.93 -1.8202 -0.9645 3562038 PK04_181197 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C#Cc4ccccc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J20 compound treatment 343520.0 -13700.0 -0.12 361290.0 50600.0 0.43 0.2211 0.4969 3562039 PK04_181198 CCCCCCC1C[C@]2(CC[C@@H](CC2)C(C)(C)C)OO1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J21 mock treatment 309290.0 -47900.0 -0.41 220520.0 -90100.0 -0.76 -0.8292 -0.9567 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J22 mock treatment 357460.0 222.0 0.0 332980.0 22300.0 0.19 0.1352 0.7141 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J23 compound treatment 216000.0 -141000.0 -1.2 288480.0 -22200.0 -0.19 -0.9827 -0.808 3562041 PK04_181199 COc1cc2CCN(CC=C)C(C#Cc3ccccc3)c2cc1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 J24 compound treatment 315360.0 -41900.0 -0.36 258910.0 -51800.0 -0.44 -0.5624 -0.9946 3562042 PK04_181200 Cc1ccc(cc1)C2C[C@]3(CC[C@@H](CC3)C(C)(C)C)OO2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K01 compound treatment 415810.0 58600.0 0.5 300960.0 -9710.0 -0.08 0.2941 0.5824 3562010 PK04_181201 C[C@H]([C@H](OC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(C(=O)[C@@H]13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4)c5ccccc5)N(C)C(=O)CCC=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K02 compound treatment 250620.0 -107000.0 -0.91 281920.0 -28700.0 -0.24 -0.8138 -0.8664 3215602 PK04_181202 Cc1c(NC(=O)/C(=C/c2ccc3ccccc3c2)/C#N)c(=O)n(c4ccccc4)n1C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K03 compound treatment 277690.0 -79500.0 -0.68 244660.0 -66000.0 -0.56 -0.8744 -0.9956 3562044 PK04_181203 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)O)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K04 compound treatment 377730.0 20500.0 0.17 157360.0 -153000.0 -1.3 -0.7963 -0.6069 3562046 PK04_181204 COc1cccc(OC)c1/C=C/C=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K05 compound treatment 172970.0 -184000.0 -1.57 276250.0 -34400.0 -0.29 -1.3149 -0.8246 2065615 PK04_181205 COc1ccc(CN2[C@H]3C(=O)N(Cc4ccccc4)C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]5[C@H]6O[C@]3(C=C6)[C@H]5C2=O)c7ccccc7)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K06 compound treatment 376800.0 19600.0 0.17 224400.0 -86300.0 -0.73 -0.3998 -0.5327 3562048 PK04_181206 Clc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K07 mock treatment 210880.0 -146000.0 -1.25 447570.0 137000.0 1.16 -0.0593 -0.0348 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K08 mock treatment 421570.0 64300.0 0.55 394030.0 83400.0 0.71 0.887 0.992 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K09 compound treatment 266370.0 -90900.0 -0.77 184230.0 -126000.0 -1.07 -1.305 -0.9871 3562049 PK04_181207 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC=C)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K10 compound treatment 415040.0 57800.0 0.49 392500.0 81800.0 0.69 0.8386 0.9857 3562051 PK04_181208 Clc1cccc(c1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K11 compound treatment 304960.0 -52300.0 -0.44 173710.0 -137000.0 -1.16 -1.136 -0.9132 3562052 PK04_181209 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K12 compound treatment 389520.0 32300.0 0.27 222640.0 -88000.0 -0.75 -0.3338 -0.4196 3562054 PK04_181210 O=C1CSCN1c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K13 compound treatment 402720.0 45500.0 0.39 307040.0 -3630.0 -0.03 0.2518 0.6488 3562052 PK04_181211 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K14 compound treatment 483840.0 127000.0 1.08 391010.0 80300.0 0.68 1.2435 0.9756 1951450 PK04_181212 Cc1c(N2C(SCC2=O)c3ccccc3)c(=O)n(c4ccccc4)n1C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K15 mock treatment 417180.0 59900.0 0.51 267640.0 -43000.0 -0.36 0.1025 0.1634 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K16 mock treatment 209760.0 -147000.0 -1.25 415940.0 105000.0 0.89 -0.2557 -0.1661 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K17 compound treatment 270720.0 -86500.0 -0.74 263840.0 -46800.0 -0.4 -0.8013 -0.9581 3562052 PK04_181213 CCCCCCN1[C@@H](C(=O)Nc2ccc(OC)cc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K18 compound treatment 359040.0 1800.0 0.02 209030.0 -102000.0 -0.86 -0.5988 -0.6944 3562055 PK04_181214 CN1C(SCC1=O)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K19 compound treatment 372760.0 15500.0 0.13 285390.0 -25300.0 -0.21 -0.0582 -0.2313 3562056 PK04_181215 COCOc1ccc2cc(Br)ccc2c1c3c(OCOC)ccc4cc(Br)ccc34 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K20 compound treatment 385520.0 28300.0 0.24 259240.0 -51400.0 -0.44 -0.1383 -0.2777 3562057 PK04_181216 O=C1CS(=O)(=O)CN1c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K21 compound treatment 232960.0 -124000.0 -1.06 275040.0 -35600.0 -0.3 -0.9613 -0.8742 3220192 PK04_181217 CC(CO)N1C2C(=O)N(Cc3ccccc3)CC=CC42OC5C=CCOC(=O)C5C4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K22 compound treatment 173540.0 -184000.0 -1.56 422920.0 112000.0 0.95 -0.4317 -0.2359 3562058 PK04_181218 CN1C(c2ccccc2)S(=O)(=O)CC1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K23 mock treatment 191770.0 -165000.0 -1.41 403540.0 92900.0 0.79 -0.4383 -0.2717 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 K24 mock treatment 340560.0 -16700.0 -0.14 343300.0 32600.0 0.28 0.0954 0.3067 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L01 compound treatment 332450.0 -24800.0 -0.21 344420.0 33800.0 0.29 0.0533 0.15 3562059 PK04_181219 COc1cc2CC[N+](=Cc2cc1OC)Cc3ccc(Br)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L02 compound treatment 477760.0 121000.0 1.03 244090.0 -66600.0 -0.56 0.3257 0.2782 3562060 PK04_181220 CCOC(=O)CCC1(C)C[C@]2(CC[C@@H](CC2)C(C)(C)C)OO1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L03 compound treatment 256600.0 -101000.0 -0.86 231550.0 -79100.0 -0.67 -1.08 -0.9927 3562062 PK04_181221 Cc1cc2ccccc2c[n+]1CCCC=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L04 compound treatment 45020.0 -312000.0 -2.66 40220.0 -270000.0 -2.29 -3.5004 -0.9973 3562063 PK04_181222 CC1(CCc2ccccc2)CC(CO)OO1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L05 compound treatment 216440.0 -141000.0 -1.2 216640.0 -94000.0 -0.8 -1.411 -0.9805 3562064 PK04_181223 COc1ccc(Br)c(C[n+]2cc3ccccc3cc2C)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L06 compound treatment 412560.0 55300.0 0.47 321140.0 10500.0 0.09 0.3956 0.826 3562065 PK04_181224 CC(C)(C)[C@H]1CC[C@]2(CC(C)(CC(C)(C)CO)OO2)CC1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L07 mock treatment 294950.0 -62300.0 -0.53 221330.0 -89300.0 -0.76 -0.9106 -0.9847 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L08 mock treatment 431970.0 74700.0 0.64 234600.0 -76100.0 -0.65 -0.0067 -0.0074 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L09 compound treatment 426120.0 68900.0 0.59 208170.0 -102000.0 -0.87 -0.2004 -0.1912 3562067 PK04_181225 CC1=[N+](C)C2C3CC=CC3C1c4ccccc24 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L10 compound treatment 205880.0 -151000.0 -1.29 123460.0 -187000.0 -1.59 -2.0334 -0.9946 3562068 PK04_181226 CC(C)(C)[C@H]1CC[C@]2(CC(C)(CCO)OO2)CC1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L11 compound treatment 446930.0 89700.0 0.76 303630.0 -7040.0 -0.06 0.4973 0.6498 1006359 PK04_181227 Cc1cccc[n+]1C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L12 compound treatment 199530.0 -158000.0 -1.34 240800.0 -69900.0 -0.59 -1.3678 -0.9325 3562070 PK04_181228 CC1(CCOCc2ccccc2)CC(C)(CCc3ccccc3)OO1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L13 compound treatment 369120.0 11900.0 0.1 375750.0 65100.0 0.55 0.4619 0.8229 3562071 PK04_181229 C[n+]1cc2ccccc2cc1C#N 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L14 compound treatment 363620.0 6380.0 0.05 209120.0 -102000.0 -0.86 -0.5707 -0.6612 3562072 PK04_181230 COc1ccc(CN/2C(C3CC3)c4ccccc4C\C2=N\P(=O)(Oc5ccccc5)Oc6ccccc6)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L15 mock treatment 432360.0 75100.0 0.64 344580.0 33900.0 0.29 0.6553 0.935 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L16 mock treatment 329600.0 -27600.0 -0.24 365520.0 54900.0 0.47 0.1628 0.3122 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L17 compound treatment 344270.0 -13000.0 -0.11 233660.0 -77000.0 -0.65 -0.5399 -0.815 3562074 PK04_181231 CCCCOC1CC2[N+](=C(C)C1c3ccccc23)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L18 compound treatment 385880.0 28600.0 0.24 353440.0 42800.0 0.36 0.4289 0.9812 3562075 PK04_181232 CCCCCCC1C[C@]2(CCC[C@@H](C)C2)OO1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L19 compound treatment 331100.0 -26100.0 -0.22 142430.0 -168000.0 -1.43 -1.1664 -0.8075 3188663 PK04_181233 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L20 compound treatment 178730.0 -179000.0 -1.52 104610.0 -206000.0 -1.75 -2.3098 -0.9975 3562077 PK04_181234 CC1(CCO)CC(C)(CCc2ccccc2)OO1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L21 compound treatment 383890.0 26700.0 0.23 391680.0 81000.0 0.69 0.6463 0.8931 3070955 PK04_181235 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L22 compound treatment 90570.0 -267000.0 -2.27 54310.0 -256000.0 -2.17 -3.1418 -0.9998 3562078 PK04_181236 COC(=O)CC1(C)CC(C)(CCc2ccccc2)OO1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L23 mock treatment 396350.0 39100.0 0.33 400960.0 90300.0 0.77 0.7769 0.9303 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 L24 mock treatment 352920.0 -4320.0 -0.04 328670.0 18000.0 0.15 0.082 0.5221 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M01 compound treatment 329440.0 -27800.0 -0.24 332240.0 21600.0 0.18 -0.0378 -0.1265 3562079 PK04_181237 CC(C)(C)N1[C@H]2C(=O)N(Cc3ccccc3)C/C=C\COC(=O)[C@@H]4[C@H]5O[C@]2(C=C5)[C@H]4C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M02 compound treatment 352860.0 -4380.0 -0.04 204680.0 -106000.0 -0.9 -0.6621 -0.7358 3562081 PK04_181238 Clc1ccccc1/C=C/C=C\2/C(=O)N(CS2(=O)=O)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M03 compound treatment 167380.0 -190000.0 -1.62 120640.0 -190000.0 -1.61 -2.2819 -1.0 3562049 PK04_181239 CC(C)(C)N1[C@@H](C(=O)N(CC=C)Cc2ccccc2)[C@]3(O[C@H]4C=C3)[C@H]([C@@H]4C(=O)OCC=C)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M04 compound treatment 6370.0 -351000.0 -2.98 4280.0 -306000.0 -2.6 -3.9484 -0.9976 3562083 PK04_181240 CN1C(c2ccccc2)S(=O)(=O)/C(=C\C=C\c3ccccc3Cl)/C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M05 compound treatment 346240.0 -11000.0 -0.09 138580.0 -172000.0 -1.46 -1.0984 -0.7509 3562085 PK04_181241 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M06 compound treatment 366090.0 8850.0 0.08 341440.0 30800.0 0.26 0.2378 0.8754 1053847 PK04_181242 O=C1CSC(N1c2ccccc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M07 compound treatment 384160.0 26900.0 0.23 225150.0 -85500.0 -0.73 -0.351 -0.4614 3562085 PK04_181243 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M08 compound treatment 217700.0 -140000.0 -1.19 229760.0 -80900.0 -0.69 -1.3247 -0.9661 3562087 PK04_181244 COc1ccccc1/C=C/C=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M09 mock treatment 442910.0 85700.0 0.73 398460.0 87800.0 0.74 1.042 0.9999 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M10 mock treatment 450340.0 93100.0 0.79 357300.0 46600.0 0.4 0.8398 0.9485 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M11 compound treatment 332560.0 -24700.0 -0.21 189450.0 -121000.0 -1.03 -0.8755 -0.8343 3562085 PK04_181245 CCOC(=O)[C@@H]1[C@H]2O[C@@]3(C=C2)[C@@H](N(CCCCCCO)C(=O)[C@@H]13)C(=O)NCc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M12 compound treatment 314350.0 -42900.0 -0.36 310780.0 113.0 0.0 -0.2573 -0.7053 3562088 PK04_181246 O=C1CS(=O)(=O)C(N1c2ccccc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M13 mock treatment 314110.0 -43100.0 -0.37 290520.0 -20100.0 -0.17 -0.3803 -0.9396 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M14 mock treatment 258610.0 -98600.0 -0.84 244930.0 -65700.0 -0.56 -0.9876 -0.9803 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M15 compound treatment 227420.0 -130000.0 -1.1 197350.0 -113000.0 -0.96 -1.4606 -0.9976 3562089 PK04_181247 CCCCCNC(=O)[C@@H]1N(C(=O)[C@H]2[C@@H]([C@H]3O[C@@]12C=C3)C(=O)OCC)c4ccccc4Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M16 compound treatment 28870.0 -328000.0 -2.79 13970.0 -297000.0 -2.52 -3.755 -0.9986 2118235 PK04_181248 [O-][N+](=O)c1cccc(/C=C/C=O)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M17 compound treatment 213920.0 -143000.0 -1.22 169280.0 -141000.0 -1.2 -1.7102 -1.0 3562089 PK04_181249 CCCCCNC(=O)[C@@H]1N(C(=O)[C@H]2[C@@H]([C@H]3O[C@@]12C=C3)C(=O)OCC)c4ccccc4Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M18 compound treatment 434620.0 77400.0 0.66 239420.0 -71200.0 -0.6 0.0381 0.0427 3562090 PK04_181250 CC(C)Cc1ccc(/C=C/C=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M19 compound treatment 375200.0 18000.0 0.15 294360.0 -16300.0 -0.14 0.0102 0.0497 3561852 PK04_181251 CCOC(=O)C1C2OC3(C=C2)C(N(C(=O)C13)C(C)(C)C)C(=O)N(CC=C)Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M20 compound treatment 254480.0 -103000.0 -0.87 161970.0 -149000.0 -1.26 -1.5101 -0.984 3215597 PK04_181252 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3cccc(c3)[N+](=O)[O-])S2(=O)=O)c4cc(C)cc(C)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M21 compound treatment 402300.0 45100.0 0.38 314830.0 4160.0 0.04 0.296 0.769 3562092 PK04_181253 O=C1C2C3C(OC42C=CCN(Cc5ccccc5)C(=O)C4N1C6CCCCC6)C=CCOC3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M22 compound treatment 417120.0 59900.0 0.51 248180.0 -62500.0 -0.53 -0.0146 -0.0198 3562093 PK04_181254 CCOc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M23 compound treatment 185680.0 -172000.0 -1.46 80010.0 -231000.0 -1.96 -2.4155 -0.9896 3562094 PK04_181255 O=C1C2C3C4OC2(C=C4)C(N1C5CCCCC5)C(=O)N(Cc6ccccc6)CCCCOC3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 M24 compound treatment 437810.0 80600.0 0.69 316650.0 5980.0 0.05 0.5206 0.7574 3562095 PK04_181256 Cc1cc(C)cc(c1)N2C(c3ccccc3)S(=O)(=O)CC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N01 compound treatment 425640.0 68400.0 0.58 178720.0 -132000.0 -1.12 -0.38 -0.3012 3188533 PK04_181257 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N02 compound treatment 425640.0 68400.0 0.58 356480.0 45800.0 0.39 0.6863 0.9807 3562096 PK04_181258 CC1(CCc2ccccc2)CC(C)(CC(=O)O)OO1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N03 compound treatment 396910.0 39700.0 0.34 422400.0 112000.0 0.95 0.9088 0.9033 3562097 PK04_181259 C=C/C=C/[C@H]1[C@@H]2[C@H](Cc3ccccc3)OC(=O)[C@H](Cc4ccccc4)N2CC1=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N04 compound treatment 409150.0 51900.0 0.44 197760.0 -113000.0 -0.96 -0.365 -0.346 3562099 PK04_181260 CC1(CCOCc2ccccc2)CC(C)(COCc3ccccc3)OO1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N05 compound treatment 427970.0 70700.0 0.6 382690.0 72000.0 0.61 0.8575 1.0 3562100 PK04_181261 Cn1c(=O)n2[C@H]3[C@@H]4[C@H](Cc5ccccc5)OC(=O)[C@H](Cc6ccccc6)N4CC3=C[C@@H](C7CC7)n2c1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N06 compound treatment 408890.0 51700.0 0.44 348220.0 37600.0 0.32 0.536 0.9875 3562102 PK04_181262 C[C@@H]1CCC[C@]2(CC(C)(CCOCc3ccccc3)OO2)C1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N07 compound treatment 349850.0 -7390.0 -0.06 289380.0 -21300.0 -0.18 -0.1721 -0.9003 3562104 PK04_181263 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3[C@H]1Cc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N08 compound treatment 378770.0 21500.0 0.18 406770.0 96100.0 0.82 0.706 0.8449 3562106 PK04_181264 CC1(C)O[C@]2(C)CC[C@@H]1OO2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N09 mock treatment 397610.0 40400.0 0.34 323250.0 12600.0 0.11 0.3183 0.8851 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N10 mock treatment 427530.0 70300.0 0.6 393470.0 82800.0 0.7 0.9195 0.9968 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N11 compound treatment 313840.0 -43400.0 -0.37 316270.0 5600.0 0.05 -0.2275 -0.611 3188666 PK04_181265 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N12 compound treatment 493280.0 136000.0 1.16 386920.0 76300.0 0.65 1.2757 0.9622 3562108 PK04_181266 CC[C@]1(CC[C@@H]2OO1)OC2(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N13 mock treatment 353530.0 -3710.0 -0.03 367090.0 56400.0 0.48 0.3161 0.6591 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N14 mock treatment 364430.0 7190.0 0.06 235170.0 -75500.0 -0.64 -0.4096 -0.6367 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N15 compound treatment 423370.0 66100.0 0.56 357200.0 46500.0 0.39 0.6769 0.985 3188536 PK04_181267 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N16 compound treatment 427220.0 70000.0 0.6 389570.0 78900.0 0.67 0.8943 0.9983 3562110 PK04_181268 CCC[C@]1(CC[C@@H]2OO1)OC2(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N17 compound treatment 374110.0 16900.0 0.14 295140.0 -15500.0 -0.13 0.0084 0.0429 3188535 PK04_181269 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N18 compound treatment 424680.0 67400.0 0.57 308770.0 -1900.0 -0.02 0.3943 0.687 3562112 PK04_181270 CC1(C)O[C@]2(CCc3ccccc3)CC[C@@H]1OO2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N19 compound treatment 386130.0 28900.0 0.25 225290.0 -85400.0 -0.72 -0.3383 -0.4423 3070940 PK04_181271 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N20 compound treatment 190300.0 -167000.0 -1.42 149810.0 -161000.0 -1.36 -1.9691 -0.9998 3562114 PK04_181272 ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc(c(o3)c4ccccc4)c5ccccc5)CC(O2)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N21 compound treatment 331200.0 -26000.0 -0.22 249500.0 -61200.0 -0.52 -0.5235 -0.928 3188534 PK04_181273 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N22 compound treatment 188240.0 -169000.0 -1.44 344450.0 33800.0 0.29 -0.814 -0.5552 3562115 PK04_181274 CC(C)(C)[C@H]1CC[C@]2(CC(C[Si](C)(C)C)OO2)CC1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N23 compound treatment 276920.0 -80300.0 -0.68 155480.0 -155000.0 -1.32 -1.414 -0.9534 3562117 PK04_181275 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@H](C4CC4)n5n([C@@H]3[C@H]2[C@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 N24 compound treatment 426350.0 69100.0 0.59 387490.0 76800.0 0.65 0.8765 0.9987 1004341 PK04_181276 c1ccc2cnccc2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O01 compound treatment 232680.0 -125000.0 -1.06 294560.0 -16100.0 -0.14 -0.8459 -0.7917 3562118 PK04_181277 CCOC(=O)[C@H]1C2OC3(C=C2)[C@H](N(C(=O)[C@H]13)c4cccc(Cl)c4CO)C(=O)NCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O02 compound treatment 209520.0 -148000.0 -1.26 80180.0 -230000.0 -1.96 -2.2711 -0.9772 3562120 PK04_181278 CCOc1ccc(cc1)N2C(c3ccccc3)S(=O)(=O)/C(=C\C=C\c4ccccc4OC)/C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O03 compound treatment 284180.0 -73100.0 -0.62 165240.0 -145000.0 -1.23 -1.3118 -0.9496 3562122 PK04_181279 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O04 compound treatment 102600.0 -255000.0 -2.17 169550.0 -141000.0 -1.2 -2.3782 -0.9609 3562124 PK04_181280 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3cccc(c3)[N+](=O)[O-])S2(=O)=O)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O05 compound treatment 376170.0 18900.0 0.16 339290.0 28600.0 0.24 0.2856 0.9801 3562122 PK04_181281 C[C@@H]1[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C(=O)N(Cc5ccccc5)C/C=C/CCC(=O)N1C)C(C)(C)C)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O06 compound treatment 170080.0 -187000.0 -1.59 161600.0 -149000.0 -1.26 -2.02 -0.9935 3562126 PK04_181282 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3ccccc3)S2(=O)=O)c4cc(C)cc(C)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O07 compound treatment 67520.0 -290000.0 -2.46 90660.0 -220000.0 -1.87 -3.0625 -0.9906 3562128 PK04_181283 CCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)C(C)(C)C)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O08 compound treatment 92920.0 -264000.0 -2.25 136880.0 -174000.0 -1.47 -2.6324 -0.979 3215600 PK04_181284 COc1ccccc1/C=C/C=C\2/C(=O)N(C(c3ccccc3)S2(=O)=O)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O09 compound treatment 103520.0 -254000.0 -2.16 89220.0 -221000.0 -1.88 -2.8545 -0.9976 3562128 PK04_181285 CCCCN1CC=C[C@@]23O[C@@H]4/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]4[C@H]3C(=O)N([C@@H]2C1=O)C(C)(C)C)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O10 compound treatment 402000.0 44800.0 0.38 230130.0 -80500.0 -0.68 -0.2138 -0.2734 3562130 PK04_181286 OCCSCC(O)CC(O)c1ccccc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O11 mock treatment 259040.0 -98200.0 -0.84 378720.0 68100.0 0.58 -0.1825 -0.1797 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O12 mock treatment 334270.0 -23000.0 -0.2 324050.0 13400.0 0.11 -0.0579 -0.2562 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O13 compound treatment 402440.0 45200.0 0.38 351390.0 40700.0 0.35 0.5162 0.9986 3561848 PK04_181287 CCCCCN1C/C=C/CCC(=O)N(C)[C@H](C)[C@H](OC(=O)[C@@H]2[C@H]3O[C@]4(C=C3)[C@H]2C(=O)N([C@H]4C1=O)c5ccccc5Cl)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O14 compound treatment 382290.0 25100.0 0.21 321330.0 10700.0 0.09 0.2147 0.9272 3562131 PK04_181288 OC(CSc1ccncc1)CC(O)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O15 compound treatment 348400.0 -8840.0 -0.08 299010.0 -11700.0 -0.1 -0.1231 -0.9909 3562132 PK04_181289 C[C@H](C(O)c1ccccc1)N(C)C(=O)CCC=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O16 compound treatment 300600.0 -56600.0 -0.48 239560.0 -71100.0 -0.6 -0.7672 -0.9938 3562134 PK04_181290 COC(=O)CCCCCCC(=O)Nc1ccc(C=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O17 compound treatment 272690.0 -84500.0 -0.72 215540.0 -95100.0 -0.81 -1.0792 -0.9984 3562132 PK04_181291 C[C@H](C(O)c1ccccc1)N(C)C(=O)CCC=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O18 compound treatment 412100.0 54900.0 0.47 259250.0 -51400.0 -0.44 0.0216 0.0338 3562135 PK04_181292 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3ccccn3)CC(O2)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O19 compound treatment 268320.0 -88900.0 -0.76 221620.0 -89000.0 -0.76 -1.069 -1.0 3561921 PK04_181293 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O20 compound treatment 207420.0 -150000.0 -1.27 215410.0 -95300.0 -0.81 -1.4726 -0.9758 3562136 PK04_181294 COC(=O)CCCCCCC(=O)Nc1ccc(cc1)C2OC(CSc3nc4ccccc4s3)CC(O2)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O21 compound treatment 181500.0 -176000.0 -1.5 196730.0 -114000.0 -0.97 -1.7406 -0.9777 3561921 PK04_181295 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O22 compound treatment 280610.0 -76600.0 -0.65 301920.0 -8750.0 -0.07 -0.5134 -0.7825 3562137 PK04_181296 OC(CC=C)c1ccc(cc1)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O23 compound treatment 287550.0 -69700.0 -0.59 243280.0 -67400.0 -0.57 -0.8234 -0.9998 3561921 PK04_181297 COc1ccc(CN2[C@@H](C(=O)N(CC=C)Cc3ccccc3)[C@]4(O[C@H]5C=C4)[C@H]([C@@H]5C(=O)OC([C@@H](C)N(C)C(=O)CCC=C)c6ccccc6)C2=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 O24 compound treatment 320710.0 -36500.0 -0.31 205920.0 -105000.0 -0.89 -0.848 -0.9009 3562138 PK04_181298 CC(C)(C)OC(=O)OC(CC=C)c1ccccc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P01 compound treatment 149640.0 -208000.0 -1.77 130080.0 -181000.0 -1.53 -2.332 -0.9975 3562139 PK04_181299 COC(=O)C1(CCCCC1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P02 compound treatment 299050.0 -58200.0 -0.5 261280.0 -49400.0 -0.42 -0.6463 -0.9966 1015751 PK04_181300 Cc1ccncc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P03 compound treatment 193330.0 -164000.0 -1.39 152320.0 -158000.0 -1.34 -1.9358 -0.9998 3562141 PK04_181301 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@H](/C=C/C3CC3)[C@@H](O)Cc4ccccc4)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P04 compound treatment 270900.0 -86300.0 -0.73 239600.0 -71100.0 -0.6 -0.9456 -0.9952 3562143 PK04_181302 COc1cc2CCN(=Cc2cc1OC)Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P05 compound treatment 207930.0 -149000.0 -1.27 264360.0 -46300.0 -0.39 -1.1759 -0.8845 3562144 PK04_181303 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=CCCC=C[C@H]4[C@@H]3[C@@H](O)Cc5ccccc5)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P06 compound treatment 279840.0 -77400.0 -0.66 253170.0 -57500.0 -0.49 -0.8105 -0.9891 1024512 PK04_181304 COc1cc2CCN=C(C)c2cc1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P07 compound treatment 192560.0 -165000.0 -1.4 160180.0 -150000.0 -1.28 -1.8933 -0.9989 3562146 PK04_181305 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3C51CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P08 compound treatment 227640.0 -130000.0 -1.1 249230.0 -61400.0 -0.52 -1.1481 -0.9415 3562148 PK04_181306 COc1cc2CC(C)N(=Cc2cc1OC)Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P09 compound treatment 213440.0 -144000.0 -1.22 239000.0 -71700.0 -0.61 -1.2949 -0.9479 3562149 PK04_181307 COC(=O)C1(CCCC1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P10 compound treatment 210270.0 -147000.0 -1.25 183570.0 -127000.0 -1.08 -1.6464 -0.9973 1003512 PK04_181308 C[n+]1ccc2ccccc2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P11 mock treatment 202050.0 -155000.0 -1.32 227200.0 -83500.0 -0.71 -1.4342 -0.9573 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P12 mock treatment 211390.0 -146000.0 -1.24 173960.0 -137000.0 -1.16 -1.6974 -0.9994 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P13 compound treatment 201530.0 -156000.0 -1.32 190120.0 -121000.0 -1.02 -1.6597 -0.9918 3562151 PK04_181309 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3C[C@](C)(OC)O[C@@H](Cc4ccccc4)[C@H]3/C=C/C5CC5)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P14 compound treatment 245220.0 -112000.0 -0.95 158240.0 -152000.0 -1.29 -1.5881 -0.9887 1009497 PK04_181310 Cc1cc[n+](C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P15 compound treatment 178910.0 -178000.0 -1.52 157240.0 -153000.0 -1.3 -1.993 -0.9971 3562153 PK04_181311 COC(=O)[C@@H]1N[C@H](SC1(C)C)[C@@H]2N(CC#C)[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P16 compound treatment 197850.0 -159000.0 -1.36 154990.0 -156000.0 -1.32 -1.8926 -0.9999 1023898 PK04_181312 COc1cc2CC[N+](=Cc2cc1OC)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P17 compound treatment 111040.0 -246000.0 -2.09 161320.0 -149000.0 -1.27 -2.3768 -0.971 3562155 PK04_181313 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC(=C[C@@H]3[C@@H](O)Cc4ccccc4)/C=C/C5CC5)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P18 compound treatment 242880.0 -114000.0 -0.97 214630.0 -96000.0 -0.81 -1.264 -0.9961 1071838 PK04_181314 COc1cc2CC[N+](=C(C)c2cc1OC)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P19 compound treatment 203390.0 -154000.0 -1.31 238560.0 -72100.0 -0.61 -1.358 -0.94 3562157 PK04_181315 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)C41CCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P20 compound treatment 202500.0 -155000.0 -1.32 152860.0 -158000.0 -1.34 -1.8774 -1.0 1023900 PK04_181316 COc1cc2CC(C)[N+](=Cc2cc1OC)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P21 compound treatment 198000.0 -159000.0 -1.35 157790.0 -153000.0 -1.3 -1.8749 -0.9998 3562159 PK04_181317 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=C[C@@H](C5CC5)n6n(C4[C@@H]3[C@@H](O)Cc7ccccc7)c(=O)n(C)c6=O)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P22 compound treatment 152640.0 -205000.0 -1.74 223330.0 -87300.0 -0.74 -1.7546 -0.9276 1107245 PK04_181318 COc1ccc(C[n+]2ccc3ccccc3c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P23 compound treatment 299800.0 -57400.0 -0.49 228650.0 -82000.0 -0.7 -0.8375 -0.9851 3562161 PK04_181319 CC(=CCc1cc(/C=C/2\OC(=O)C(=C2O)c3cc4CCC(C)(C)Oc4cc3O)ccc1O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2181 P24 compound treatment 214790.0 -142000.0 -1.21 213920.0 -96700.0 -0.82 -1.4372 -0.982 3562163 PK04_181320 COc1ccc(C[n+]2ccc(C)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A01 compound treatment 252920.0 -212000.0 -1.8 259720.0 -209000.0 -1.77 -2.5274 -1.0 1952677 BCB03_000001 CCCCCCC#Cc1c(C(CC(=O)C)c2ccccc2)c(=O)oc3ccccc13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A02 compound treatment 458090.0 -6340.0 -0.05 475640.0 6680.0 0.06 0.0019 0.0248 3092787 BCB03_000002 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A03 compound treatment 410370.0 -54100.0 -0.46 456040.0 -12900.0 -0.11 -0.4027 -0.8518 1952679 BCB03_000003 Clc1ccc2oc(=O)cc(Sc3ccccc3)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A04 compound treatment 460320.0 -4110.0 -0.03 416580.0 -52400.0 -0.44 -0.3389 -0.7604 3092788 BCB03_000004 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccc2C(F)(F)F)c3ccccc3C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A05 compound treatment 403740.0 -60700.0 -0.52 271320.0 -198000.0 -1.68 -1.5506 -0.8839 1952690 BCB03_000005 COC(=O)CC(C(=O)OC)c1ccccc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A06 compound treatment 254330.0 -210000.0 -1.79 208820.0 -260000.0 -2.21 -2.8242 -0.9945 3001175 BCB03_000006 CON(C)C(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A07 compound treatment 280350.0 -184000.0 -1.57 455970.0 -13000.0 -0.11 -1.1853 -0.755 1952707 BCB03_000007 CCCCSc1cc(=O)oc2cc(OC)ccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A08 compound treatment 360120.0 -104000.0 -0.89 478430.0 9470.0 0.08 -0.5707 -0.6405 3001176 BCB03_000008 CC(C)OC(=O)CC(=O)CC(O)c1ccc(cc1)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A09 compound treatment 355010.0 -109000.0 -0.93 380000.0 -89000.0 -0.75 -1.1918 -0.9946 1952793 BCB03_000009 FC(F)(F)c1ccc(cc1)C(=O)Oc2ccccc2C#Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A10 compound treatment 472060.0 7630.0 0.06 425680.0 -43300.0 -0.37 -0.2137 -0.5732 3001249 BCB03_000010 CC(C)OC(=O)CC(=O)CC(O)c1cccc(c1)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A11 compound treatment 529870.0 65400.0 0.56 448680.0 -20300.0 -0.17 0.272 0.4668 1952795 BCB03_000011 COC(=O)/C=C/c1cc(OC)cc(C#Cc2ccc(Oc3ccccc3)c(OC)c2)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A12 compound treatment 440710.0 -23700.0 -0.2 303400.0 -166000.0 -1.4 -1.1357 -0.8005 3001250 BCB03_000012 CC(C)OC(=O)CC(=O)CC(O)c1cccc(C#N)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A13 mock treatment 432330.0 -32100.0 -0.27 450720.0 -18200.0 -0.15 -0.3025 -0.9638 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A14 mock treatment 342830.0 -122000.0 -1.03 506790.0 37800.0 0.32 -0.5046 -0.4659 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A15 compound treatment 477250.0 12800.0 0.11 317160.0 -152000.0 -1.29 -0.8334 -0.6449 1952801 BCB03_000013 Oc1ccccc1C#Cc2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A16 compound treatment 488180.0 23800.0 0.2 504370.0 35400.0 0.3 0.3553 0.9814 3001251 BCB03_000014 CC(C)OC(=O)CC(=O)CC(O)c1ccc(C#N)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A17 compound treatment 477860.0 13400.0 0.11 465850.0 -3110.0 -0.03 0.0621 0.5299 1952761 BCB03_000015 COc1ccc(cc1)C(=C2C(=O)Oc3ccccc23)c4ccc(OC)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A18 compound treatment 348010.0 -116000.0 -0.99 414200.0 -54800.0 -0.46 -1.0288 -0.9404 3001252 BCB03_000016 COC(=O)C1=CCC(CC1)(C=C)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A19 compound treatment 306400.0 -158000.0 -1.34 328450.0 -141000.0 -1.19 -1.7934 -0.9982 1952804 BCB03_000017 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCCCC2)c1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A20 compound treatment 281930.0 -182000.0 -1.55 390560.0 -78400.0 -0.67 -1.5681 -0.9284 3001253 BCB03_000018 COC(=O)/C=C(/CC(O)c1cccc(Cl)c1)\OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A21 compound treatment 373400.0 -91000.0 -0.77 372640.0 -96300.0 -0.82 -1.1253 -0.9996 1952805 BCB03_000019 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(cc2c(coc12)C(O)(c3ccccc3)c4ccccc4)c5cc(I)cc(I)c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A22 compound treatment 447690.0 -16700.0 -0.14 476320.0 7360.0 0.06 -0.0565 -0.3637 3001254 BCB03_000020 OC(C/C(=C/C(=O)OCCF)/OCCF)c1cccc(Cl)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A23 compound treatment 442720.0 -21700.0 -0.18 381620.0 -87300.0 -0.74 -0.6545 -0.8571 1952808 BCB03_000021 CCCCCc1cc2ccccc2o1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 A24 compound treatment 295390.0 -169000.0 -1.44 373470.0 -95500.0 -0.81 -1.5896 -0.9631 3001255 BCB03_000022 CCO/C(=C\C(=O)OC)/CC(O)c1cccc(Cl)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B01 compound treatment 512480.0 48100.0 0.41 481400.0 12400.0 0.11 0.3637 0.8614 3000770 BCB03_000023 Cc1ccc(cc1)S(=O)(=O)N2C[C@H]([C@@H](C[C@H]2c3ccccc3)Sc4ccccc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B02 compound treatment 354970.0 -109000.0 -0.93 265360.0 -204000.0 -1.73 -1.8797 -0.958 3070361 BCB03_000024 CN1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B03 compound treatment 489490.0 25100.0 0.21 499200.0 30200.0 0.26 0.3321 0.9958 3000771 BCB03_000025 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B04 compound treatment 421800.0 -42600.0 -0.36 511710.0 42800.0 0.36 0.0 0.0 3189527 BCB03_000026 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B05 compound treatment 430350.0 -34100.0 -0.29 469920.0 960.0 0.01 -0.1992 -0.687 3092495 BCB03_000027 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B06 compound treatment 306480.0 -158000.0 -1.34 330560.0 -138000.0 -1.17 -1.7803 -0.9977 3189528 BCB03_000028 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)/C(=N\P(=O)(Oc6ccccc6)Oc7ccccc7)/C2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B07 compound treatment 388680.0 -75700.0 -0.64 458880.0 -10100.0 -0.09 -0.5161 -0.794 3092496 BCB03_000029 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B08 compound treatment 498100.0 33700.0 0.29 429250.0 -39700.0 -0.34 -0.0356 -0.0806 3189529 BCB03_000030 CN1C(=O)C2C(C3C(C4CC4)N(C)C2C=C3c5ccc(CO)cc5)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B09 compound treatment 503520.0 39100.0 0.33 392190.0 -76800.0 -0.65 -0.2253 -0.3081 3000773 BCB03_000031 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B10 compound treatment 446130.0 -18300.0 -0.16 433700.0 -35300.0 -0.3 -0.3216 -0.9537 3070364 BCB03_000032 CN1C(=O)C2C(C3C(N(C)C2C=C3CCCO)c4ccc(CN5CCCC5)cc4)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B11 compound treatment 371230.0 -93200.0 -0.79 366080.0 -103000.0 -0.87 -1.1777 -0.9989 3000774 BCB03_000033 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B12 compound treatment 389490.0 -74900.0 -0.64 406180.0 -62800.0 -0.53 -0.8274 -0.996 3189532 BCB03_000034 CN/1C(C=C(CCCO)C\C1=N\P(=O)(Oc2ccccc2)Oc3ccccc3)c4cccs4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B13 mock treatment 514420.0 50000.0 0.43 467560.0 -1400.0 -0.01 0.2923 0.6871 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B14 mock treatment 432520.0 -31900.0 -0.27 456080.0 -12900.0 -0.11 -0.2692 -0.92 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B15 compound treatment 503620.0 39200.0 0.33 419560.0 -49400.0 -0.42 -0.0606 -0.1131 3000775 BCB03_000035 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B16 compound treatment 395840.0 -68600.0 -0.58 523050.0 54100.0 0.46 -0.0882 -0.1188 3189533 BCB03_000036 CC1C=C(CCCO)C/C(=N/P(=O)(Oc2ccccc2)Oc3ccccc3)/N1Cc4cccc(OC(F)(F)F)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B17 compound treatment 445700.0 -18700.0 -0.16 426790.0 -42200.0 -0.36 -0.3656 -0.9336 3092507 BCB03_000037 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B18 compound treatment 301460.0 -163000.0 -1.39 412640.0 -56300.0 -0.48 -1.3182 -0.8989 3189534 BCB03_000038 CN1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B19 compound treatment 460800.0 -3630.0 -0.03 375520.0 -93400.0 -0.79 -0.5823 -0.7341 3092508 BCB03_000039 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B20 compound treatment 378170.0 -86300.0 -0.73 386310.0 -82600.0 -0.7 -1.0146 -0.9997 3070367 BCB03_000040 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B21 compound treatment 205250.0 -259000.0 -2.2 419320.0 -49600.0 -0.42 -1.8569 -0.8272 3000857 BCB03_000041 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(F)cc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B22 compound treatment 429440.0 -35000.0 -0.3 388120.0 -80800.0 -0.69 -0.6954 -0.9302 3189537 BCB03_000042 CN1C(=O)C2C(C3C(N(C)C2C=C3c4ccc(CO)cc4)c5cccs5)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B23 compound treatment 462760.0 -1670.0 -0.01 364700.0 -104000.0 -0.88 -0.6354 -0.7184 3000858 BCB03_000043 CCOC(=O)C1=C[C@H](N([C@H]1c2ccc(Cl)c(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 B24 compound treatment 278140.0 -186000.0 -1.58 202610.0 -266000.0 -2.26 -2.7182 -0.985 3189538 BCB03_000044 CN1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C01 compound treatment 465880.0 1450.0 0.01 446990.0 -22000.0 -0.19 -0.123 -0.6588 1952809 BCB03_000045 CC(=O)Oc1ccccc1C#Cc2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C02 compound treatment 434610.0 -29800.0 -0.25 371390.0 -97600.0 -0.83 -0.7646 -0.8833 3092872 BCB03_000046 FCCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C03 compound treatment 434880.0 -29500.0 -0.25 406140.0 -62800.0 -0.53 -0.5546 -0.9412 1952811 BCB03_000047 CC(C)(C)[Si](C)(C)Oc1ccc(C#C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C04 compound treatment 288840.0 -176000.0 -1.49 359840.0 -109000.0 -0.93 -1.7108 -0.9735 3000746 BCB03_000048 CC(C)OC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C05 compound treatment 429240.0 -35200.0 -0.3 310600.0 -158000.0 -1.34 -1.1616 -0.844 1952813 BCB03_000049 OCCCC#Cc1cc(O)cc(Cl)c1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C06 compound treatment 450790.0 -13600.0 -0.12 445780.0 -23200.0 -0.2 -0.2211 -0.9683 3000748 BCB03_000050 CCOC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C07 compound treatment 440580.0 -23800.0 -0.2 420830.0 -48100.0 -0.41 -0.4322 -0.9479 1952814 BCB03_000051 CC(=O)Cc1c(Cl)cc(cc1I)C(=O)NCCO[Si](C)(C)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C08 compound treatment 431900.0 -32500.0 -0.28 435000.0 -34000.0 -0.29 -0.3994 -0.9998 3000750 BCB03_000052 COC(=O)C1=CCC(O1)c2cccc(Cl)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C09 compound treatment 444660.0 -19800.0 -0.17 456040.0 -12900.0 -0.11 -0.1964 -0.9785 1952821 BCB03_000053 CC(C)(C)[Si](C)(C)COCNC(=O)C1CC2C3C(OC2C(Cl)C1)C4(CCCC4)OC3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C10 compound treatment 382050.0 -82400.0 -0.7 408820.0 -60100.0 -0.51 -0.8563 -0.9878 2065163 BCB03_000054 CCOC(=O)/C=C/c1ccccc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C11 mock treatment 480640.0 16200.0 0.14 363520.0 -105000.0 -0.89 -0.5349 -0.5911 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C12 mock treatment 473820.0 9390.0 0.08 481820.0 12900.0 0.11 0.1336 0.9883 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C13 compound treatment 267600.0 -197000.0 -1.67 335040.0 -134000.0 -1.14 -1.9873 -0.9821 1952823 BCB03_000055 C#Cc1ccccc1Oc2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C14 compound treatment 364020.0 -100000.0 -0.85 435360.0 -33600.0 -0.29 -0.8056 -0.8946 3000752 BCB03_000056 CCOC(=O)/C=C/c1cc(F)ccc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C15 mock treatment 453160.0 -11300.0 -0.1 461310.0 -7650.0 -0.06 -0.1137 -0.9819 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C16 mock treatment 385230.0 -79200.0 -0.67 384000.0 -85000.0 -0.72 -0.986 -0.9994 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C17 compound treatment 381880.0 -82500.0 -0.7 401610.0 -67300.0 -0.57 -0.9006 -0.9948 1952825 BCB03_000057 CCCC(C)(O)C#Cc1cc(cc(C(=O)NCCO[Si](C)(C)C(C)(C)C)c1OC(=O)C)c2cc(F)cc(F)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C18 compound treatment 484160.0 19700.0 0.17 438720.0 -30200.0 -0.26 -0.0627 -0.2045 3000753 BCB03_000058 CCOC(=O)/C=C/c1cc(ccc1O)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C19 compound treatment 21980.0 -442000.0 -3.76 40760.0 -428000.0 -3.63 -5.23 -0.9998 1952828 BCB03_000059 CCc1cc(OC)c(O)c(C#CC(O)c2ccccc2)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C20 compound treatment 434240.0 -30200.0 -0.26 413630.0 -55300.0 -0.47 -0.5135 -0.9597 3000754 BCB03_000060 CCOC(=O)/C=C/c1cccc(OC)c1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C21 compound treatment 452270.0 -12200.0 -0.1 433530.0 -35400.0 -0.3 -0.2857 -0.8987 1952829 BCB03_000061 O=C(/C(=C\c1ccccc1)/c2cccc(c2)S(=O)=O)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C22 compound treatment 453330.0 -11100.0 -0.09 434190.0 -34800.0 -0.29 -0.2753 -0.889 3000755 BCB03_000062 CCOC(=O)/C=C/c1cccc(C)c1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C23 compound treatment 424570.0 -39900.0 -0.34 407480.0 -61500.0 -0.52 -0.6085 -0.9783 1952832 BCB03_000063 CCc1cc(OC)c(O)c(C#CC(C)(O)C=C)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 C24 compound treatment 287040.0 -177000.0 -1.51 308880.0 -160000.0 -1.36 -2.0273 -0.9986 3000762 BCB03_000064 CCOC(=O)/C=C/c1ccccc1OC(=O)C#CC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D01 compound treatment 270240.0 -194000.0 -1.65 483520.0 14600.0 0.12 -1.0808 -0.6524 3000859 BCB03_000065 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc(Cl)c2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D02 compound treatment 314340.0 -150000.0 -1.28 372320.0 -96600.0 -0.82 -1.4825 -0.9771 3189665 BCB03_000066 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)/C(=N\P(=O)(Oc3ccccc3)Oc4ccccc4)/C1)c5ccc(CN6CCCC6)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D03 compound treatment 494410.0 30000.0 0.26 448520.0 -20400.0 -0.17 0.0578 0.1873 3092513 BCB03_000067 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2Cl)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D04 compound treatment 475390.0 11000.0 0.09 280000.0 -189000.0 -1.6 -1.0675 -0.6648 3189666 BCB03_000068 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)/C(=N\P(=O)(Oc5ccccc5)Oc6ccccc6)/C1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D05 compound treatment 307890.0 -157000.0 -1.33 436800.0 -32200.0 -0.27 -1.1346 -0.8346 3092514 BCB03_000069 CCOC(=O)C1=C[C@H](N([C@H]1c2cccc3ccccc23)S(=O)(=O)c4ccc(C)cc4)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D06 compound treatment 299700.0 -165000.0 -1.4 361200.0 -108000.0 -0.91 -1.6373 -0.9786 3189668 BCB03_000070 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)/C(=N\P(=O)(Oc4ccccc4)Oc5ccccc5)/C1)c6ccc(CN7CCCC7)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D07 compound treatment 318300.0 -146000.0 -1.24 410880.0 -58100.0 -0.49 -1.2274 -0.9179 3000861 BCB03_000071 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(F)(F)F)S(=O)(=O)c3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D08 compound treatment 451220.0 -13200.0 -0.11 406620.0 -62300.0 -0.53 -0.4534 -0.8386 3189669 BCB03_000072 CN1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D09 compound treatment 440360.0 -24100.0 -0.2 479450.0 10500.0 0.09 -0.0819 -0.3667 3092596 BCB03_000073 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccc(cc2)C(C)C)S(=O)(=O)c3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D10 compound treatment 430010.0 -34400.0 -0.29 468390.0 -570.0 0.0 -0.2105 -0.7187 3189670 BCB03_000074 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D11 mock treatment 510720.0 46300.0 0.39 444440.0 -24500.0 -0.21 0.1314 0.295 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D12 mock treatment 402750.0 -61700.0 -0.52 439760.0 -29200.0 -0.25 -0.5462 -0.9413 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D13 compound treatment 423650.0 -40800.0 -0.35 464200.0 -4760.0 -0.04 -0.2739 -0.7841 3000869 BCB03_000075 CCOC(=O)C1=C[C@@H](C(C)C)N([C@H]1c2ccccc2F)S(=O)(=O)c3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D14 compound treatment 337890.0 -127000.0 -1.08 476610.0 7650.0 0.06 -0.7153 -0.6633 3070434 BCB03_000076 NC(=O)N1C(=O)C2C(C3C(N(Cc4sc5ccccc5c4Cl)C2C=C3CCCO)c6ccc(CN7CCCC7)cc6)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D15 mock treatment 490450.0 26000.0 0.22 341570.0 -127000.0 -1.08 -0.6076 -0.5508 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D16 mock treatment 399360.0 -65100.0 -0.55 461970.0 -6990.0 -0.06 -0.4333 -0.7784 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D17 compound treatment 363680.0 -101000.0 -0.86 443700.0 -25300.0 -0.21 -0.7576 -0.8575 3000870 BCB03_000077 CCOC(=O)C1=C[C@@H](CC)N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D18 compound treatment 377040.0 -87400.0 -0.74 384670.0 -84300.0 -0.72 -1.0313 -0.9998 3189673 BCB03_000078 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5cccs5)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D19 compound treatment 374240.0 -90200.0 -0.77 345010.0 -124000.0 -1.05 -1.286 -0.988 3092599 BCB03_000079 CCOC(=O)C1=CCN(C1c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D20 compound treatment 356320.0 -108000.0 -0.92 416260.0 -52700.0 -0.45 -0.9664 -0.9451 3189674 BCB03_000080 OCc1ccc(cc1)C2=CC(N(Cc3cccc(OC(F)(F)F)c3)CC2)c4cccs4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D21 compound treatment 319450.0 -145000.0 -1.23 384340.0 -84600.0 -0.72 -1.3797 -0.9668 3092600 BCB03_000081 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)OCC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D22 compound treatment 226400.0 -238000.0 -2.02 230320.0 -239000.0 -2.02 -2.8633 -1.0 3070436 BCB03_000082 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3c7ccc(CO)cc7)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D23 compound treatment 382940.0 -81500.0 -0.69 412290.0 -56700.0 -0.48 -0.8301 -0.984 3092601 BCB03_000083 CCOC(=O)C1=C[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 D24 compound treatment 425120.0 -39300.0 -0.33 481120.0 12200.0 0.1 -0.1635 -0.4673 3070437 BCB03_000084 CN1CCC(=CC1C2CC2)CCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E01 mock treatment 526280.0 61900.0 0.53 506940.0 38000.0 0.32 0.5999 0.9723 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E02 mock treatment 504390.0 40000.0 0.34 433940.0 -35000.0 -0.3 0.0303 0.0672 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E03 mock treatment 504570.0 40100.0 0.34 514160.0 45200.0 0.38 0.5126 0.9983 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E04 compound treatment 502290.0 37900.0 0.32 414200.0 -54800.0 -0.46 -0.1007 -0.1782 3093836 BCB03_000085 CCOC(=O)[C@H]1CC=C2[C@@H]1c3ccccc3OC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E05 compound treatment 505250.0 40800.0 0.35 504030.0 35100.0 0.3 0.4559 0.997 1952837 BCB03_000086 COCCNC(=O)c1ccc(c(C#CC(C)(O)CC(C)C)c1O)c2cc(F)cc(F)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E06 compound treatment 456690.0 -7740.0 -0.07 421870.0 -47100.0 -0.4 -0.329 -0.8127 3000764 BCB03_000087 CCOC(=O)[C@H]1CC=C2[C@@H]1c3cc(Br)ccc3OC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E07 compound treatment 500120.0 35700.0 0.3 483090.0 14100.0 0.12 0.2995 0.9174 1952838 BCB03_000088 COc1cc(CO[Si](C)(C)C(C)(C)C)cc(C#CC2(O)CCC3C2CC4Cc5cc(O)ccc5C43)c1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E08 compound treatment 436290.0 -28100.0 -0.24 371280.0 -97700.0 -0.83 -0.7552 -0.8756 3000765 BCB03_000089 CCOC(=O)/C=C/c1cc(Br)ccc1OC(=O)C#CC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E09 mock treatment 496910.0 32500.0 0.28 505040.0 36100.0 0.31 0.4118 0.9987 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E10 mock treatment 492720.0 28300.0 0.24 520060.0 51100.0 0.43 0.4767 0.9615 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E11 compound treatment 486290.0 21900.0 0.19 453300.0 -15700.0 -0.13 0.0376 0.1644 1952839 BCB03_000090 Oc1ccccc1C#CC#Cc2ccccc2O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E12 compound treatment 276640.0 -188000.0 -1.6 247100.0 -222000.0 -1.88 -2.4604 -0.9967 3000766 BCB03_000091 O=c1oc2ccccc2cc1C#C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E13 compound treatment 487690.0 23300.0 0.2 449320.0 -19600.0 -0.17 0.0221 0.0855 1952842 BCB03_000092 COC(=O)Cc1cc(cc(I)c1O)c2cc(F)cc(I)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E14 compound treatment 344740.0 -120000.0 -1.02 315760.0 -153000.0 -1.3 -1.6389 -0.9927 3000767 BCB03_000093 Cn1c2C3NC(C(=O)c2c4ccccc14)C(C)(C=C3)C(=O)OCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E15 compound treatment 209640.0 -255000.0 -2.17 179560.0 -289000.0 -2.45 -3.2686 -0.9981 2065685 BCB03_000094 CCOCOc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OCOCC)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E16 compound treatment 364900.0 -99500.0 -0.85 298620.0 -170000.0 -1.44 -1.6205 -0.9676 3000768 BCB03_000095 [O-][N+](=O)c1ccccc1S(=O)(=O)N2C3CC=C(C2C(=O)c4c3[nH]c5ccccc45)C(=O)OCc6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E17 mock treatment 455680.0 -8750.0 -0.07 393450.0 -75500.0 -0.64 -0.5055 -0.784 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E18 mock treatment 414650.0 -49800.0 -0.42 389550.0 -79400.0 -0.67 -0.7758 -0.975 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E19 compound treatment 349980.0 -114000.0 -0.97 315530.0 -153000.0 -1.3 -1.6088 -0.9898 2065729 BCB03_000096 CCOCOc1cc(OCOCC)c2C(=O)CC(Oc2c1)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E20 compound treatment 370440.0 -94000.0 -0.8 440230.0 -28700.0 -0.24 -0.7377 -0.8825 3093843 BCB03_000097 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E21 compound treatment 441720.0 -22700.0 -0.19 354370.0 -115000.0 -0.97 -0.8239 -0.8314 1952773 BCB03_000098 CCCNC(=O)c1cc(cc2c3C(=O)OC4(CCCC4)c3oc12)c5cc(F)cc(F)c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E22 compound treatment 363000.0 -101000.0 -0.86 402500.0 -66500.0 -0.56 -1.0088 -0.9787 3000776 BCB03_000099 CCOC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(CC)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E23 compound treatment 294400.0 -170000.0 -1.45 364200.0 -105000.0 -0.89 -1.6512 -0.9726 1952780 BCB03_000100 COc1cccc(c1)c2c(oc3ccccc23)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 E24 compound treatment 217520.0 -247000.0 -2.1 372230.0 -96700.0 -0.82 -2.0655 -0.9159 3000848 BCB03_000101 CCOC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(CC)C2=O)Sc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F01 mock treatment 352850.0 -112000.0 -0.95 492500.0 23500.0 0.2 -0.53 -0.5464 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F02 mock treatment 477680.0 13300.0 0.11 435230.0 -33700.0 -0.29 -0.1226 -0.3987 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F03 compound treatment 532120.0 67700.0 0.58 503590.0 34600.0 0.29 0.6149 0.9512 3000874 BCB03_000102 Cc1ccc(cc1)[C@@H]2N(CC=C2C(=O)O)S(=O)(=O)c3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F04 compound treatment 417170.0 -47300.0 -0.4 455870.0 -13100.0 -0.11 -0.3628 -0.8698 3187712 BCB03_000103 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4ccc(CN5CCCC5)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F05 compound treatment 324720.0 -140000.0 -1.19 438640.0 -30300.0 -0.26 -1.0223 -0.8407 3092602 BCB03_000104 C[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F06 compound treatment 481710.0 17300.0 0.15 483560.0 14600.0 0.12 0.1915 0.9964 3187713 BCB03_000105 CN1C(C2CC2)C3C4C(C1C=C3c5ccc(CO)cc5)C(=O)N(C(=O)N)C4=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F07 compound treatment 488720.0 24300.0 0.21 519630.0 50700.0 0.43 0.4501 0.9437 3092680 BCB03_000106 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F08 compound treatment 452810.0 -11600.0 -0.1 454310.0 -14600.0 -0.12 -0.1578 -0.9936 3187714 BCB03_000107 OCCCC1=CC(C2CC2)N(Cc3cc4OCOc4cc3Br)CC1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F09 mock treatment 317350.0 -147000.0 -1.25 465700.0 -3260.0 -0.03 -0.9043 -0.7226 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F10 mock treatment 441180.0 -23200.0 -0.2 420320.0 -48600.0 -0.41 -0.4316 -0.9433 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F11 compound treatment 397410.0 -67000.0 -0.57 439910.0 -29000.0 -0.25 -0.5774 -0.9296 3092681 BCB03_000108 CCC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F12 compound treatment 398990.0 -65400.0 -0.56 474450.0 5490.0 0.05 -0.3607 -0.6457 3070498 BCB03_000109 CC1C=C(CCCO)CCN1Cc2cccc(OC(F)(F)F)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F13 compound treatment 523370.0 58900.0 0.5 433670.0 -35300.0 -0.3 0.1429 0.2447 3000959 BCB03_000110 CC(C)[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F14 compound treatment 299320.0 -165000.0 -1.4 445350.0 -23600.0 -0.2 -1.1348 -0.7998 3070499 BCB03_000111 CN1CCC(=CC1c2cccs2)c3ccc(CO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F15 compound treatment 487420.0 23000.0 0.2 531720.0 62800.0 0.53 0.5148 0.9076 3092683 BCB03_000112 Cc1ccc(cc1)[C@@H]2N([C@@H](C=C2C(=O)O)C(C)(C)C)S(=O)(=O)c3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F16 compound treatment 464110.0 -319.0 0.0 301020.0 -168000.0 -1.42 -1.0093 -0.7085 3187718 BCB03_000113 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4cccs4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F17 mock treatment 426610.0 -37800.0 -0.32 422420.0 -46500.0 -0.39 -0.5067 -0.9948 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F18 mock treatment 315360.0 -149000.0 -1.27 469250.0 290.0 0.0 -0.895 -0.7057 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F19 compound treatment 450880.0 -13500.0 -0.12 462170.0 -6790.0 -0.06 -0.1222 -0.9486 3092684 BCB03_000114 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccccc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F20 compound treatment 274090.0 -190000.0 -1.62 316580.0 -152000.0 -1.29 -2.059 -0.9938 3187719 BCB03_000115 OCCCC1=CC(N(Cc2sc3ccccc3c2Cl)CC1)c4ccc(CN5CCCC5)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F21 compound treatment 436160.0 -28300.0 -0.24 393940.0 -75000.0 -0.64 -0.62 -0.9114 3000962 BCB03_000116 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F22 compound treatment 241060.0 -223000.0 -1.9 278100.0 -191000.0 -1.62 -2.4885 -0.9968 3187720 BCB03_000117 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4sc5ccccc5c4Cl)CC2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F23 compound treatment 428160.0 -36300.0 -0.31 439450.0 -29500.0 -0.25 -0.3952 -0.9946 3092686 BCB03_000118 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 F24 compound treatment 343900.0 -121000.0 -1.03 314130.0 -155000.0 -1.31 -1.6537 -0.9925 3070502 BCB03_000119 CN1C(C2C3C(C1C=C2c4ccc(CO)cc4)C(=O)N(C(=O)N)C3=O)c5cccs5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G01 compound treatment 384450.0 -80000.0 -0.68 494720.0 25800.0 0.22 -0.3266 -0.457 3107406 BCB03_000120 COC(=O)/C=C/c1cc(OC)c2oc(c(C)c2c1)c3ccccc3.c1ccsc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G02 compound treatment 496490.0 32100.0 0.27 513120.0 44200.0 0.37 0.4577 0.9878 3000850 BCB03_000121 OC(=O)C1=CC[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G03 mock treatment 524960.0 60500.0 0.51 431040.0 -37900.0 -0.32 0.1367 0.2251 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G04 mock treatment 506560.0 42100.0 0.36 525950.0 57000.0 0.48 0.5953 0.9892 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G05 compound treatment 422670.0 -41800.0 -0.36 480730.0 11800.0 0.1 -0.1806 -0.4894 1952785 BCB03_000122 CCc1cc(OC)c2oc(c(C(=O)c3ccccc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G06 compound treatment 498400.0 34000.0 0.29 509360.0 40400.0 0.34 0.4467 0.9964 3092501 BCB03_000123 OC(=O)[C@H]1[C@H](C[C@@H]2[C@H]1C(=O)N(C2=O)c3ccccc3)Sc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G07 compound treatment 511170.0 46700.0 0.4 517600.0 48600.0 0.41 0.5729 0.9998 1952788 BCB03_000124 CCc1cc(OC)c2oc(c(C(=O)c3ccc(OC)cc3)c2c1)c4ccc(Oc5ccccc5)c(OC)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G08 compound treatment 469520.0 5090.0 0.04 497570.0 28600.0 0.24 0.2022 0.8203 3092502 BCB03_000125 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G09 compound treatment 417120.0 -47300.0 -0.4 504550.0 35600.0 0.3 -0.0711 -0.1413 2065776 BCB03_000126 Cc1ccc(SC2(CC(=O)N(Cc3ccccc3)C2c4ccccc4I)C(=O)NCc5ccccc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G10 compound treatment 480390.0 16000.0 0.14 478690.0 9730.0 0.08 0.1544 0.9715 3000853 BCB03_000127 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G11 compound treatment 412390.0 -52000.0 -0.44 500320.0 31400.0 0.27 -0.1249 -0.2419 1034979 BCB03_000128 c1c(cn2ccccc12)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G12 compound treatment 458790.0 -5640.0 -0.05 468580.0 -380.0 0.0 -0.0362 -0.7529 3000854 BCB03_000129 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G13 compound treatment 301650.0 -163000.0 -1.38 513390.0 44400.0 0.38 -0.7127 -0.4966 2065809 BCB03_000130 COC(=O)Cc1cn[nH]c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G14 compound treatment 425840.0 -38600.0 -0.33 475810.0 6850.0 0.06 -0.191 -0.573 3000855 BCB03_000131 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G15 compound treatment 506760.0 42300.0 0.36 473690.0 4730.0 0.04 0.283 0.7811 2065826 BCB03_000132 CC(C(=O)O)c1ccccc1C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G16 compound treatment 400430.0 -64000.0 -0.54 452480.0 -16500.0 -0.14 -0.4838 -0.8607 3000862 BCB03_000133 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2C)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G17 compound treatment 500180.0 35800.0 0.3 482490.0 13500.0 0.11 0.2962 0.9112 2065840 BCB03_000134 CCOC(=O)CC(CC(=O)OCC)(C(=O)OCC)c1cccnc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G18 compound treatment 458880.0 -5550.0 -0.05 313830.0 -155000.0 -1.32 -0.9639 -0.732 3000863 BCB03_000135 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)C[Si](C)(C)C)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G19 mock treatment 471940.0 7510.0 0.06 400850.0 -68100.0 -0.58 -0.3633 -0.6251 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G20 mock treatment 511200.0 46800.0 0.4 446620.0 -22300.0 -0.19 0.1474 0.3344 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G21 compound treatment 413990.0 -50400.0 -0.43 462300.0 -6660.0 -0.06 -0.3434 -0.7934 2065855 BCB03_000136 CCOC(=O)CC(C(=O)OCC)c1cccnc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G22 compound treatment 350080.0 -114000.0 -0.97 399360.0 -69600.0 -0.59 -1.1053 -0.9714 3092589 BCB03_000137 CCOC(=O)C1=CC[C@H](N([C@H]1/C=C/c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G23 compound treatment 14080.0 -450000.0 -3.83 13240.0 -456000.0 -3.87 -5.4426 -1.0 2065872 BCB03_000138 CCOC(=O)/C(=C/1\NSc2ccccc12)/C#N 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 G24 compound treatment 424270.0 -40200.0 -0.34 342080.0 -127000.0 -1.08 -1.0026 -0.8879 3092590 BCB03_000139 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4cccc(Cl)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H01 compound treatment 340810.0 -124000.0 -1.05 516420.0 47500.0 0.4 -0.459 -0.4076 3092687 BCB03_000140 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H02 compound treatment 447170.0 -17300.0 -0.15 478880.0 9920.0 0.08 -0.0443 -0.2619 3187850 BCB03_000141 OCCCC1=CC(C2CC2)N(Cc3cccc(OC(F)(F)F)c3)CC1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H03 mock treatment 478800.0 14400.0 0.12 514280.0 45300.0 0.38 0.3583 0.8882 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H04 mock treatment 551360.0 86900.0 0.74 554960.0 86000.0 0.73 1.0388 1.0 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H05 compound treatment 412450.0 -52000.0 -0.44 517870.0 48900.0 0.41 -0.0193 -0.0318 3092697 BCB03_000142 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H06 compound treatment 374140.0 -90300.0 -0.77 472730.0 3770.0 0.03 -0.5205 -0.6771 3187852 BCB03_000143 CN1C(C2C3C(C1C=C2CCCO)C(=O)N(C(=O)N)C3=O)c4ccc(CN5CCCC5)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H07 compound treatment 319690.0 -145000.0 -1.23 404910.0 -64000.0 -0.54 -1.2549 -0.9324 3092698 BCB03_000144 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccco3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H08 compound treatment 346000.0 -118000.0 -1.01 419060.0 -49900.0 -0.42 -1.0117 -0.9258 3187853 BCB03_000145 CC1C2C3C(C(C=C2CCCO)N1Cc4cccc(OC(F)(F)F)c4)C(=O)N(C(=O)N)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H09 compound treatment 533500.0 69100.0 0.59 500600.0 31600.0 0.27 0.6053 0.937 3092699 BCB03_000146 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H10 compound treatment 454970.0 -9460.0 -0.08 531250.0 62300.0 0.53 0.3167 0.5926 3070552 BCB03_000147 OCCCC1=CC(C2CC2)N(Cc3sc4ccccc4c3Cl)CC1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H11 compound treatment 457050.0 -7380.0 -0.06 515040.0 46100.0 0.39 0.232 0.586 3092700 BCB03_000148 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(Br)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H12 compound treatment 414750.0 -49700.0 -0.42 236600.0 -232000.0 -1.97 -1.6926 -0.8396 3070553 BCB03_000149 CN1CCC(=CC1c2cccs2)CCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H13 compound treatment 423520.0 -40900.0 -0.35 513120.0 44200.0 0.37 0.0188 0.0368 3000975 BCB03_000150 CC[C@@H]1C=C([C@@H](N1S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)C(C)C)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H14 compound treatment 268340.0 -196000.0 -1.67 481860.0 12900.0 0.11 -1.1022 -0.6593 3187856 BCB03_000151 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H15 compound treatment 447850.0 -16600.0 -0.14 446570.0 -22400.0 -0.19 -0.234 -0.9893 3000976 BCB03_000152 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](C=C([C@@H]2c3ccccc3)C(=O)O)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H16 compound treatment 401330.0 -63100.0 -0.54 400400.0 -68600.0 -0.58 -0.7908 -0.9992 3187857 BCB03_000153 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3CCCO)c5ccc(CN6CCCC6)cc5)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H17 compound treatment 407680.0 -56700.0 -0.48 272200.0 -197000.0 -1.67 -1.5216 -0.8757 3092773 BCB03_000154 CC(C)[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H18 compound treatment 356730.0 -108000.0 -0.92 386770.0 -82200.0 -0.7 -1.1409 -0.9909 3070555 BCB03_000155 OCc1ccc(cc1)C2=CC(C3CC3)N(Cc4cc5OCOc5cc4Br)CC2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H19 mock treatment 368480.0 -95900.0 -0.82 477700.0 8740.0 0.07 -0.5248 -0.6402 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H20 mock treatment 484000.0 19600.0 0.17 417640.0 -51300.0 -0.44 -0.1901 -0.4079 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H21 compound treatment 406250.0 -58200.0 -0.49 470290.0 1330.0 0.01 -0.342 -0.6908 3092774 BCB03_000156 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H22 compound treatment 326720.0 -138000.0 -1.17 313570.0 -155000.0 -1.32 -1.7605 -0.9983 3070556 BCB03_000157 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5sc6ccccc6c5Cl)C2C=C3CCCO)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H23 compound treatment 305520.0 -159000.0 -1.35 377500.0 -91500.0 -0.78 -1.5045 -0.9652 3092783 BCB03_000158 CCC[C@@H]1[C@@H](Sc2ccccc2)[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 H24 compound treatment 285130.0 -179000.0 -1.53 362490.0 -106000.0 -0.9 -1.7172 -0.9687 3070597 BCB03_000159 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3c7ccc(CO)cc7)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I01 compound treatment 407680.0 -56700.0 -0.48 489860.0 20900.0 0.18 -0.216 -0.42 2065633 BCB03_000160 CCOC(=O)CC(C#N)(C(=O)OCC)c1nsc2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I02 compound treatment 512210.0 47800.0 0.41 512760.0 43800.0 0.37 0.5502 0.999 3000865 BCB03_000161 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2I)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I03 compound treatment 331210.0 -133000.0 -1.13 529800.0 60800.0 0.52 -0.4365 -0.3505 2065650 BCB03_000162 [O-][N+](=O)c1ccc(OS(=O)(=O)C(F)(F)F)c(I)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I04 compound treatment 517870.0 53400.0 0.45 494720.0 25800.0 0.22 0.476 0.9436 3000866 BCB03_000163 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I05 mock treatment 544030.0 79600.0 0.68 525990.0 57000.0 0.48 0.8209 0.9864 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I06 mock treatment 488700.0 24300.0 0.21 540600.0 71600.0 0.61 0.5757 0.897 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I07 compound treatment 215300.0 -249000.0 -2.12 229540.0 -239000.0 -2.03 -2.9347 -0.9998 1065064 BCB03_000164 [O-][N+](=O)c1ccc(CBr)c(I)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I08 compound treatment 401830.0 -62600.0 -0.53 469520.0 560.0 0.0 -0.3732 -0.7008 3000867 BCB03_000165 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I09 compound treatment 490670.0 26200.0 0.22 410770.0 -58200.0 -0.49 -0.1912 -0.3529 2065874 BCB03_000166 COC(=O)C(C(=O)OC)c1ccc(cc1I)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I10 compound treatment 338610.0 -126000.0 -1.07 466600.0 -2360.0 -0.02 -0.771 -0.7202 3092595 BCB03_000167 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(SC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCc5ccccc5)c(OC)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I11 compound treatment 505870.0 41400.0 0.35 481340.0 12400.0 0.11 0.3236 0.8795 BCB03_000168 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I12 compound treatment 442240.0 -22200.0 -0.19 397880.0 -71100.0 -0.6 -0.5598 -0.8861 3000949 BCB03_000169 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(cc2)[N+](=O)[O-])S(=O)(=O)c3ccc(C)cc3)c4cccc(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I13 compound treatment 4860.0 -460000.0 -3.91 5120.0 -464000.0 -3.93 -5.5468 -1.0 3107360 BCB03_000170 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I14 compound treatment 517920.0 53500.0 0.46 468040.0 -920.0 -0.01 0.3163 0.6949 3000951 BCB03_000171 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I15 compound treatment 360800.0 -104000.0 -0.88 364180.0 -105000.0 -0.89 -1.2519 -1.0 1952728 BCB03_000172 Cc1ccc2oc(=O)cc(c3cccs3)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I16 compound treatment 458970.0 -5460.0 -0.05 405240.0 -63700.0 -0.54 -0.415 -0.765 3000952 BCB03_000173 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc4ccccc34 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I17 compound treatment 489880.0 25500.0 0.22 450080.0 -18900.0 -0.16 0.0399 0.148 1952730 BCB03_000174 O=c1cc(Cc2ccccc2)c3ccccc3o1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I18 compound treatment 507800.0 43400.0 0.37 457960.0 -11000.0 -0.09 0.1949 0.5122 3092606 BCB03_000175 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(F)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I19 compound treatment 108540.0 -356000.0 -3.03 124880.0 -344000.0 -2.92 -4.2047 -0.9998 1952746 BCB03_000176 Cc1ccc(cc1)c2cc(=O)oc3ccccc23 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I20 compound treatment 416090.0 -48300.0 -0.41 432430.0 -36500.0 -0.31 -0.5099 -0.9903 3092607 BCB03_000177 CCOC(=O)[C@@H]1N([C@@H](CC=C1C(=O)OCC)c2ccccc2)S(=O)(=O)c3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I21 mock treatment 459530.0 -4900.0 -0.04 493320.0 24400.0 0.21 0.1166 0.5534 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I22 mock treatment 341710.0 -123000.0 -1.04 352750.0 -116000.0 -0.99 -1.4353 -0.9996 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I23 compound treatment 497870.0 33400.0 0.28 476960.0 8000.0 0.07 0.2492 0.8519 3005760 BCB03_000178 CCOP(=O)(O)OCC.Cc1cc(=O)oc2ccc(Cl)cc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 I24 compound treatment 350610.0 -114000.0 -0.97 394800.0 -74200.0 -0.63 -1.1295 -0.9782 3000954 BCB03_000179 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OC)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J01 compound treatment 513000.0 48600.0 0.41 292280.0 -177000.0 -1.5 -0.7676 -0.4937 3092784 BCB03_000180 CCS[C@@H]1[C@@H](CC)N([C@H]([C@@H]1C(=O)O)c2ccc(C)cc2)S(=O)(=O)c3ccc(C)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J02 compound treatment 418720.0 -45700.0 -0.39 453280.0 -15700.0 -0.13 -0.369 -0.8979 3187985 BCB03_000181 NC(=O)N1C(=O)C2C(C3C(N(Cc4cc5OCOc5cc4Br)C2C=C3CCCO)c6cccs6)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J03 compound treatment 226050.0 -238000.0 -2.03 327930.0 -141000.0 -1.2 -2.2799 -0.9683 3092785 BCB03_000182 CCOC1=C2C(N(CC2C3C(C1)C(=O)N(C3=O)c4ccccc4)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J04 compound treatment 372050.0 -92400.0 -0.79 492970.0 24000.0 0.2 -0.4117 -0.5071 3187986 BCB03_000183 CN1CCC(=CC1c2ccc(CN3CCCC3)cc2)CCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J05 mock treatment 529370.0 64900.0 0.55 436550.0 -32400.0 -0.27 0.1963 0.318 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J06 mock treatment 434880.0 -29500.0 -0.25 472710.0 3750.0 0.03 -0.1553 -0.6127 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J07 compound treatment 512000.0 47600.0 0.4 490740.0 21800.0 0.18 0.4168 0.9369 3001173 BCB03_000184 CCOC1=C2C(N(CC2n3n(C1)c(=O)n(c4ccccc4)c3=O)S(=O)(=O)c5ccc(C)cc5)c6ccc(C)cc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J08 compound treatment 345020.0 -119000.0 -1.02 211170.0 -258000.0 -2.19 -2.2646 -0.9392 3070607 BCB03_000185 OCCCC1=CC(N(Cc2cccc(OC(F)(F)F)c2)CC1)c3ccc(CN4CCCC4)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J09 compound treatment 433510.0 -30900.0 -0.26 398360.0 -70600.0 -0.6 -0.6095 -0.9318 3001174 BCB03_000186 Cc1ccc(cc1)C2C3C(CN2S(=O)(=O)c4ccc(C)cc4)C5C(CC3=O)C(=O)N(C5=O)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J10 compound treatment 450470.0 -14000.0 -0.12 477880.0 8920.0 0.08 -0.0305 -0.2163 3070608 BCB03_000187 OCCCC1=CC(N(Cc2cc3OCOc3cc2Br)CC1)c4cccs4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J11 compound treatment 501640.0 37200.0 0.32 406400.0 -62600.0 -0.53 -0.1514 -0.245 3092789 BCB03_000188 CCN1C(=O)C2CC(=O)C3C(N(CC3C2C1=O)S(=O)(=O)c4ccc(C)cc4)c5ccc(C)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J12 compound treatment 444770.0 -19700.0 -0.17 350260.0 -119000.0 -1.01 -0.8302 -0.8134 3070609 BCB03_000189 CN1CCC(=CC1C2CC2)c3ccc(CO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J13 compound treatment 485930.0 21500.0 0.18 453680.0 -15300.0 -0.13 0.0377 0.1681 3092790 BCB03_000190 CC[C@@H]1[C@@H]2[C@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J14 compound treatment 408200.0 -56200.0 -0.48 401680.0 -67300.0 -0.57 -0.7418 -0.9961 3187991 BCB03_000191 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cc6OCOc6cc5Br)C2C=C3CCCO)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J15 compound treatment 515600.0 51200.0 0.44 446760.0 -22200.0 -0.19 0.1747 0.3683 3092866 BCB03_000192 CC[C@@H]1[C@H]2[C@@H]([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)CC5C2C(=O)N(CC)C5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J16 compound treatment 472680.0 8250.0 0.07 470980.0 2020.0 0.02 0.0618 0.8546 3187992 BCB03_000193 NC(=O)N1C(=O)C2C(C3C(C4CC4)N(Cc5cccc(OC(F)(F)F)c5)C2C=C3CCCO)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J17 compound treatment 521290.0 56900.0 0.48 414970.0 -54000.0 -0.46 0.0182 0.0273 3092867 BCB03_000194 CCOC(=O)C1=CC[C@H](N([C@H]1CC)S(=O)(=O)c2ccc(C)cc2)c3ccc(OC)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J18 compound treatment 462350.0 -2080.0 -0.02 318890.0 -150000.0 -1.27 -0.9127 -0.7169 3187993 BCB03_000195 CN1C(C2CC2)C3C4C(C1C=C3CCCO)C(=O)N(C(=O)N)C4=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J19 compound treatment 337300.0 -127000.0 -1.08 401600.0 -67400.0 -0.57 -1.1688 -0.9555 3092868 BCB03_000196 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J20 compound treatment 262400.0 -202000.0 -1.72 351090.0 -118000.0 -1.0 -1.9223 -0.9668 3187994 BCB03_000197 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C3CC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J21 mock treatment 416120.0 -48300.0 -0.41 484730.0 15800.0 0.13 -0.196 -0.4535 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J22 mock treatment 348360.0 -116000.0 -0.99 427060.0 -41900.0 -0.36 -0.9495 -0.9048 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J23 compound treatment 437620.0 -26800.0 -0.23 396750.0 -72200.0 -0.61 -0.5944 -0.9094 3092869 BCB03_000198 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccc(Cl)c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 J24 compound treatment 376640.0 -87800.0 -0.75 392820.0 -76100.0 -0.65 -0.9848 -0.9974 3070656 BCB03_000199 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)CCCO)C(=O)OCCS(=O)(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K01 compound treatment 530730.0 66300.0 0.56 532000.0 63000.0 0.53 0.777 0.9996 3005761 BCB03_000200 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K02 compound treatment 512430.0 48000.0 0.41 365050.0 -104000.0 -0.88 -0.3345 -0.3444 3000955 BCB03_000201 CCOC(=O)C1=CC[C@H](N([C@H]1C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K03 compound treatment 460320.0 -4110.0 -0.03 536910.0 68000.0 0.58 0.3829 0.663 1952748 BCB03_000202 O=Cc1cccc(c1)c2cc(=O)oc3ccccc23 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K04 compound treatment 484740.0 20300.0 0.17 436590.0 -32400.0 -0.27 -0.072 -0.2219 3092688 BCB03_000203 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccncc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K05 compound treatment 93620.0 -371000.0 -3.15 61670.0 -407000.0 -3.45 -4.6736 -0.999 1107217 BCB03_000204 Cc1cccnc1I 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K06 compound treatment 358400.0 -106000.0 -0.9 448160.0 -20800.0 -0.18 -0.7626 -0.8297 3000965 BCB03_000205 CCOC(=O)C1=CC[C@H](N([C@H]1C=C(C)C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K07 mock treatment 434790.0 -29600.0 -0.25 498050.0 29100.0 0.25 -0.0038 -0.0108 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K08 mock treatment 494600.0 30200.0 0.26 534930.0 66000.0 0.56 0.5772 0.9375 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K09 compound treatment 549210.0 84800.0 0.72 441830.0 -27100.0 -0.23 0.3473 0.4587 3005761 BCB03_000206 Cc1ccc(cc1)S(=O)(=O)O.Cc1cc(=O)oc2ccc(Cl)cc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K10 compound treatment 439840.0 -24600.0 -0.21 465620.0 -3340.0 -0.03 -0.1679 -0.7956 3000966 BCB03_000207 CCOC(=O)C1=CC[C@H](N([C@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K11 compound treatment 402040.0 -62400.0 -0.53 456000.0 -13000.0 -0.11 -0.453 -0.8358 1952755 BCB03_000208 C=C(c1ccccc1)c2cc(=O)oc3ccccc23 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K12 compound treatment 561490.0 97100.0 0.83 529470.0 60500.0 0.51 0.9468 0.9738 3092692 BCB03_000209 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(OC)c2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K13 compound treatment 566500.0 102000.0 0.87 480590.0 11600.0 0.1 0.6838 0.7824 1952760 BCB03_000210 CC(C)(C)[Si](C)(C)OCCNC(=O)c1cc(c2cc(F)cc(F)c2)c3oc4c(C(=O)OC4(c5ccccc5)c6ccccc6)c3c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K14 compound treatment 589670.0 125000.0 1.07 568050.0 99100.0 0.84 1.3478 0.9931 3092693 BCB03_000211 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(C#N)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K15 mock treatment 553710.0 89300.0 0.76 513210.0 44300.0 0.38 0.8025 0.9472 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K16 mock treatment 483360.0 18900.0 0.16 530400.0 61400.0 0.52 0.4824 0.8844 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K17 compound treatment 464490.0 61.2 0.0 434820.0 -34100.0 -0.29 -0.2044 -0.7058 1952770 BCB03_000212 O=C/1Oc2ccccc2C\C1=C(/c3ccccc3)\c4ccc5ccccc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K18 compound treatment 515300.0 50900.0 0.43 513040.0 44100.0 0.37 0.5704 0.9973 3000969 BCB03_000213 CCOC(=O)C1=CC[C@H](N([C@H]1C=C)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K19 compound treatment 427050.0 -37400.0 -0.32 417800.0 -51200.0 -0.43 -0.5317 -0.9883 3000871 BCB03_000214 O=c1cccc(o1)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K20 compound treatment 471920.0 7490.0 0.06 455050.0 -13900.0 -0.12 -0.0384 -0.2861 3001047 BCB03_000215 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(c(OC)c4)c5ccc(OCc6ccccc6)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K21 compound treatment 424230.0 -40200.0 -0.34 464040.0 -4920.0 -0.04 -0.2713 -0.7876 3000872 BCB03_000216 COc1cccc(c1)c2cccc(=O)o2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K22 compound treatment 532540.0 68100.0 0.58 227170.0 -242000.0 -2.05 -1.0406 -0.4882 3001048 BCB03_000217 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccccc2)S(=O)(=O)c3ccc(C)cc3)c4ccc(cc4)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K23 mock treatment 408070.0 -56400.0 -0.48 528160.0 59200.0 0.5 0.0161 0.0231 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 K24 mock treatment 430730.0 -33700.0 -0.29 398950.0 -70000.0 -0.59 -0.6226 -0.9442 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L01 compound treatment 372250.0 -92200.0 -0.78 475560.0 6600.0 0.06 -0.5149 -0.655 3092870 BCB03_000218 CCOC(=O)C1=CC[C@H](N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L02 compound treatment 502400.0 38000.0 0.32 389930.0 -79000.0 -0.67 -0.2456 -0.3301 3188115 BCB03_000219 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4cccs4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L03 compound treatment 484160.0 19700.0 0.17 530720.0 61800.0 0.52 0.4891 0.8891 3092871 BCB03_000220 CCOC(=O)C1=CC[C@H](N([C@H]1c2cccc(Br)c2)S(=O)(=O)c3ccc(C)cc3)c4ccc(OCC=C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L04 compound treatment 465280.0 851.0 0.01 432800.0 -36200.0 -0.31 -0.2118 -0.6902 3188116 BCB03_000221 CC1C=C(CCCO)C=C(C(=O)OCCS(=O)(=O)C)C(=CN1Cc2cccc(OC(F)(F)F)c2)C(=O)OCCS(=O)(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L05 compound treatment 548230.0 83800.0 0.71 527300.0 58300.0 0.49 0.854 0.9841 3092774 BCB03_000222 CC[C@@H]1C(Sc2ccccc2)C([C@@H](N1S(=O)(=O)c3ccc(C)cc3)c4ccc(C)cc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L06 compound treatment 452760.0 -11700.0 -0.1 478000.0 9040.0 0.08 -0.016 -0.1273 3188117 BCB03_000223 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L07 mock treatment 455610.0 -8820.0 -0.08 497150.0 28200.0 0.24 0.116 0.463 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L08 mock treatment 559150.0 94700.0 0.81 501950.0 33000.0 0.28 0.7677 0.8999 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L09 compound treatment 532590.0 68200.0 0.58 510920.0 42000.0 0.36 0.6617 0.9725 3187870 BCB03_000224 COC(=O)C[C@H]1O[C@@H](CCc2ccccc2)[C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L10 compound treatment 447750.0 -16700.0 -0.14 460980.0 -7980.0 -0.07 -0.1482 -0.9427 3188119 BCB03_000225 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L11 compound treatment 520260.0 55800.0 0.47 492770.0 23800.0 0.2 0.4787 0.9274 3071511 BCB03_000226 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(I)cc52 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L12 compound treatment 419810.0 -44600.0 -0.38 425120.0 -43800.0 -0.37 -0.5314 -0.9999 3188120 BCB03_000227 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3cccs3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L13 compound treatment 419380.0 -45000.0 -0.38 446320.0 -22600.0 -0.19 -0.4068 -0.949 3187872 BCB03_000228 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(Cc4ccccc4)c5ccc(NC(=O)C)cc52 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L14 compound treatment 454930.0 -9500.0 -0.08 455200.0 -13800.0 -0.12 -0.1397 -0.9839 3188122 BCB03_000229 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CO)cc3)c4cccs4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L15 mock treatment 548210.0 83800.0 0.71 492090.0 23100.0 0.2 0.6427 0.8694 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L16 mock treatment 538240.0 73800.0 0.63 530130.0 61200.0 0.52 0.8109 0.9955 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L17 compound treatment 509770.0 45300.0 0.39 512580.0 43600.0 0.37 0.5344 0.9998 3414061 BCB03_000230 COC(=O)C[C@@H]1C[C@H](C)[C@]2(O1)C(=O)N(Cc3ccccc3)c4ccc(NC(=O)C)cc42 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L18 compound treatment 505600.0 41200.0 0.35 406140.0 -62800.0 -0.53 -0.1291 -0.2025 3188123 BCB03_000231 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2cccs2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L19 compound treatment 510980.0 46600.0 0.4 529490.0 60500.0 0.51 0.6431 0.9918 3071513 BCB03_000232 CC(C)[Si](OCC[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)O)C(=O)N(Cc3ccccc3)c4ccccc42)(C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L20 compound treatment 324250.0 -140000.0 -1.19 323810.0 -145000.0 -1.23 -1.7139 -0.9999 3188124 BCB03_000233 CS(=O)(=O)CCOC(=O)C1=CN(Cc2sc3ccccc3c2Cl)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L21 compound treatment 486280.0 21900.0 0.19 479470.0 10500.0 0.09 0.1945 0.9434 3071514 BCB03_000234 COc1ccc(cc1)[Si](C)(C)[C@H]2[C@H](C)[C@]3(O[C@@H]2CCO)C(=O)N(Cc4ccccc4)c5ccccc53 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L22 compound treatment 469630.0 5200.0 0.04 413920.0 -55000.0 -0.47 -0.2988 -0.6372 3188125 BCB03_000235 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CN5CCCC5)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L23 mock treatment 443590.0 -20800.0 -0.18 484750.0 15800.0 0.13 -0.0306 -0.1379 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 L24 mock treatment 468580.0 4150.0 0.04 442840.0 -26100.0 -0.22 -0.1317 -0.587 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M01 compound treatment 484810.0 20400.0 0.17 507680.0 38700.0 0.33 0.3549 0.9554 1984103 BCB03_000236 Cc1ccc(cc1)c2cccc(=O)o2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M02 compound treatment 429690.0 -34700.0 -0.3 427970.0 -41000.0 -0.35 -0.4548 -0.9967 3001049 BCB03_000237 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(cc3)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M03 compound treatment 501940.0 37500.0 0.32 470560.0 1600.0 0.01 0.2353 0.7365 3000873 BCB03_000238 Clc1cccc(c1)c2cccc(=O)o2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M04 compound treatment 515840.0 51400.0 0.44 521070.0 52100.0 0.44 0.6218 1.0 3092778 BCB03_000239 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(CC)cc2)S(=O)(=O)c3ccc(C)cc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M05 compound treatment 524600.0 60200.0 0.51 549540.0 80600.0 0.68 0.8453 0.9898 3000875 BCB03_000240 Clc1ccccc1c2cccc(=O)o2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M06 compound treatment 453620.0 -10800.0 -0.09 444110.0 -24800.0 -0.21 -0.2141 -0.9309 3001168 BCB03_000241 CCOC(=O)C1=C(N([C@@H](CC1)c2ccccc2)S(=O)(=O)CC[Si](C)(C)C)C(=O)OCC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M07 compound treatment 496600.0 32200.0 0.27 578960.0 110000.0 0.93 0.8533 0.8775 3000956 BCB03_000242 CCCc1cccc(=O)o1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M08 compound treatment 480960.0 16500.0 0.14 510370.0 41400.0 0.35 0.3478 0.9193 3092780 BCB03_000243 CCOC(=O)C1=CC[C@H](N([C@H]1c2ccc(OC)cc2)S(=O)(=O)c3ccc(C)cc3)c4cc(Cl)ccc4Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M09 mock treatment 517920.0 53500.0 0.46 498740.0 29800.0 0.25 0.5004 0.9614 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M10 mock treatment 515730.0 51300.0 0.44 529870.0 60900.0 0.52 0.674 0.9965 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M11 compound treatment 548910.0 84500.0 0.72 512360.0 43400.0 0.37 0.7685 0.9517 3000957 BCB03_000244 Fc1ccc(cc1)c2cccc(=O)o2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M12 compound treatment 563100.0 98700.0 0.84 510270.0 41300.0 0.35 0.8414 0.9249 3092781 BCB03_000245 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(cc2)[N+](=O)[O-])c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M13 mock treatment 533080.0 68700.0 0.58 566720.0 97800.0 0.83 0.9994 0.9853 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M14 mock treatment 481000.0 16600.0 0.14 530650.0 61700.0 0.52 0.4697 0.8667 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M15 compound treatment 519410.0 55000.0 0.47 553780.0 84800.0 0.72 0.8395 0.9782 3000958 BCB03_000246 O=c1cccc(o1)c2ccc(C#N)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M16 compound treatment 220450.0 -244000.0 -2.08 243370.0 -226000.0 -1.91 -2.8208 -0.9992 3001177 BCB03_000247 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccco3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M17 compound treatment 525240.0 60800.0 0.52 520320.0 51400.0 0.44 0.6739 0.9963 3092682 BCB03_000248 FC(F)(F)c1ccc(cc1)c2cccc(=O)o2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M18 compound treatment 512710.0 48300.0 0.41 448290.0 -20700.0 -0.18 0.1665 0.3727 3001178 BCB03_000249 CCOC(=O)C1=CC[C@H](N([C@@H]1C#N)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M19 compound treatment 515520.0 51100.0 0.43 497860.0 28900.0 0.25 0.4807 0.9633 3000960 BCB03_000250 FC(F)(F)c1ccccc1c2cccc(=O)o2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M20 compound treatment 426130.0 -38300.0 -0.33 475590.0 6630.0 0.06 -0.1906 -0.5765 3001179 BCB03_000251 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)CC[Si](C)(C)C)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M21 compound treatment 476800.0 12400.0 0.11 386880.0 -82100.0 -0.7 -0.4179 -0.5935 3000961 BCB03_000252 O=c1cccc(o1)c2ccc3ccccc3c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M22 compound treatment 283760.0 -181000.0 -1.54 274300.0 -195000.0 -1.65 -2.2544 -0.9994 3001245 BCB03_000253 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3cccn3C(=O)OC(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M23 compound treatment 509520.0 45100.0 0.38 411080.0 -57900.0 -0.49 -0.0759 -0.1219 3092685 BCB03_000254 O=c1cccc(o1)c2ccco2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 M24 compound treatment 411170.0 -53300.0 -0.45 494310.0 25400.0 0.22 -0.1683 -0.3356 3001246 BCB03_000255 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccc(C#N)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N01 compound treatment 442670.0 -21800.0 -0.19 431160.0 -37800.0 -0.32 -0.3576 -0.9659 3071515 BCB03_000256 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(C)cc3)C(=O)N(C)c4ccccc42 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N02 compound treatment 463700.0 -729.0 -0.01 486530.0 17600.0 0.15 0.101 0.6771 3188247 BCB03_000257 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)CCCO)C(=O)OCCS(=O)(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N03 compound treatment 493540.0 29100.0 0.25 493090.0 24100.0 0.2 0.3199 0.9955 3071516 BCB03_000258 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccc(OC)cc3)C(=O)N(C)c4ccccc42 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N04 compound treatment 460280.0 -4150.0 -0.04 489000.0 20000.0 0.17 0.0952 0.5486 3188248 BCB03_000259 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)C4CC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N05 compound treatment 484960.0 20500.0 0.17 396120.0 -72800.0 -0.62 -0.3134 -0.4881 3414062 BCB03_000260 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)c3ccccc3)C(=O)N(C)c4ccccc42 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N06 compound treatment 368960.0 -95500.0 -0.81 360540.0 -108000.0 -0.92 -1.2246 -0.9981 3188250 BCB03_000261 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cc3OCOc3cc2Br)C(C=C(C=C1C(=O)OCCS(=O)(=O)C)c4ccc(CO)cc4)C5CC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N07 compound treatment 349300.0 -115000.0 -0.98 453210.0 -15700.0 -0.13 -0.787 -0.7962 3188927 BCB03_000262 COC(=O)C[C@H]1O[C@@]2([C@@H](C)[C@@H]1[Si](C)(C)F)C(=O)N(C)c3ccccc32 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N08 compound treatment 452770.0 -11700.0 -0.1 477880.0 8920.0 0.08 -0.0166 -0.1333 3188251 BCB03_000263 CS(=O)(=O)CCOC(=O)C1=CN(Cc2cccc(OC(F)(F)F)c2)C(C=C(CCCO)C=C1C(=O)OCCS(=O)(=O)C)c3ccc(CN4CCCC4)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N09 mock treatment 533690.0 69300.0 0.59 476500.0 7540.0 0.06 0.4619 0.7793 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N10 mock treatment 537480.0 73100.0 0.62 518750.0 49800.0 0.42 0.7381 0.9823 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N11 compound treatment 514280.0 49900.0 0.42 512840.0 43900.0 0.37 0.5631 0.9979 3071435 BCB03_000264 COC(=O)C[C@H]1O[C@@]2(C[C@@H]1[Si](C)(C)C)C(=O)N(C)c3ccccc32 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N12 compound treatment 476730.0 12300.0 0.1 503140.0 34200.0 0.29 0.279 0.9052 3188252 BCB03_000265 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1C2CC2)c3ccc(CO)cc3)C(=O)OCCS(=O)(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N13 mock treatment 467310.0 2880.0 0.02 502420.0 33500.0 0.28 0.218 0.7653 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N14 mock treatment 555040.0 90600.0 0.77 518150.0 49200.0 0.42 0.8401 0.9585 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N15 compound treatment 530520.0 66100.0 0.56 516680.0 47700.0 0.4 0.6838 0.987 3188929 BCB03_000266 COC(=O)C/C=C/C[C@]1(O)C(=O)N(C)c2ccccc21 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N16 compound treatment 470240.0 5810.0 0.05 517930.0 49000.0 0.42 0.3287 0.7857 3188253 BCB03_000267 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)c3ccc(CO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N17 compound treatment 493210.0 28800.0 0.24 445320.0 -23600.0 -0.2 0.0313 0.099 3188930 BCB03_000268 COc1ccc(cc1)[Si](C)(C)[C@H](CCn2cc(CCO[Si](C(C)C)(C(C)C)C(C)C)nn2)/C=C/C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N18 compound treatment 444770.0 -19700.0 -0.17 463400.0 -5560.0 -0.05 -0.1516 -0.8725 3188254 BCB03_000269 CN1C=C(C(=O)OCCS(=O)(=O)C)C(=CC(=CC1c2ccc(CN3CCCC3)cc2)CCCO)C(=O)OCCS(=O)(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N19 compound treatment 449730.0 -14700.0 -0.13 485510.0 16600.0 0.14 0.0109 0.0577 3071465 BCB03_000270 CCCCNC(=O)c1ccc(C#CC(C)(C)C)c(OC(=O)C)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N20 compound treatment 332340.0 -132000.0 -1.12 364960.0 -104000.0 -0.88 -1.4184 -0.9928 3188255 BCB03_000271 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)CCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N21 compound treatment 501510.0 37100.0 0.32 453160.0 -15800.0 -0.13 0.1283 0.3743 1952196 BCB03_000272 CCCCNC(=O)c1ccc(C#C[Si](C)(C)C)c(OC(=O)C)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N22 compound treatment 378750.0 -85700.0 -0.73 374970.0 -94000.0 -0.8 -1.0792 -0.999 3188256 BCB03_000273 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2sc3ccccc3c2Cl)c4ccc(CN5CCCC5)cc4)CCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N23 compound treatment 470600.0 6170.0 0.05 387520.0 -81400.0 -0.69 -0.4514 -0.6515 3071510 BCB03_000274 CCCCNC(=O)c1ccc(C#C[Si](C(C)C)(C(C)C)C(C)C)c(OC(=O)C)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 N24 compound treatment 379840.0 -84600.0 -0.72 475300.0 6340.0 0.05 -0.4708 -0.6524 3188257 BCB03_000275 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2cccs2)CCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O01 compound treatment 242150.0 -222000.0 -1.89 294450.0 -175000.0 -1.48 -2.3839 -0.9927 3000963 BCB03_000276 O=c1cccc(CCc2ccccc2)o1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O02 compound treatment 388730.0 -75700.0 -0.64 396440.0 -72500.0 -0.62 -0.8904 -0.9997 3001247 BCB03_000277 CCOC(=O)C1=CCC(NC1)c2cc3ccccc3[nH]2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O03 compound treatment 482900.0 18500.0 0.16 409280.0 -59700.0 -0.51 -0.2469 -0.4657 3000971 BCB03_000278 [O-][N+](=O)c1ccc(cc1)c2cccc(=O)o2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O04 compound treatment 395160.0 -69300.0 -0.59 382040.0 -86900.0 -0.74 -0.9381 -0.9938 3001248 BCB03_000279 CCOC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccccc2[N+](=O)[O-])c3cc4ccccc4[nH]3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O05 compound treatment 461880.0 -2550.0 -0.02 429120.0 -39800.0 -0.34 -0.2543 -0.7509 3000972 BCB03_000280 O=c1cccc(/C=C/c2ccccc2)o1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O06 compound treatment 460560.0 -3870.0 -0.03 415780.0 -53200.0 -0.45 -0.3423 -0.7567 3000756 BCB03_000281 CCOC(=O)C1=CCC(N(CCN2CC(=CCC2c3cc4ccccc4[nH]3)C(=O)OCC)C1)c5cc6ccccc6[nH]5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O07 compound treatment 466080.0 1650.0 0.01 366980.0 -102000.0 -0.87 -0.6018 -0.6955 3000973 BCB03_000282 O=c1cccc(o1)c2cccc3ccccc23 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O08 compound treatment 335300.0 -129000.0 -1.1 339710.0 -129000.0 -1.1 -1.552 -1.0 3000757 BCB03_000283 CC(=O)C1=CCC(N(C1)S(=O)(=O)c2ccc(C)cc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O09 compound treatment 443840.0 -20600.0 -0.18 487060.0 18100.0 0.15 -0.0153 -0.0656 3000974 BCB03_000284 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(Cl)c2)c3cccc(Cl)c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O10 compound treatment 470820.0 6390.0 0.05 434120.0 -34800.0 -0.3 -0.1705 -0.5675 3093828 BCB03_000285 Cc1ccc(cc1)[C@@H]2C[C@@H](Sc3ccccc3)[C@@H](CN2S(=O)(=O)c4ccc(C)cc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O11 mock treatment 505600.0 41200.0 0.35 462160.0 -6800.0 -0.06 0.2069 0.5828 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O12 mock treatment 458530.0 -5900.0 -0.05 512580.0 43600.0 0.37 0.2262 0.6057 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O13 compound treatment 461390.0 -3040.0 -0.03 419730.0 -49200.0 -0.42 -0.3136 -0.7494 3092701 BCB03_000286 CCOC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)[N+](=O)[O-])c3cccc(c3)[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O14 compound treatment 478840.0 14400.0 0.12 460590.0 -8370.0 -0.07 0.0365 0.2576 3093829 BCB03_000287 Cc1ccc(cc1)C2CC=C(CN2S(=O)(=O)c3ccc(C)cc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O15 compound treatment 470360.0 5930.0 0.05 361220.0 -108000.0 -0.91 -0.6106 -0.6671 3092771 BCB03_000288 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccccn2)c3ccccn3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O16 compound treatment 457950.0 -6480.0 -0.06 491200.0 22200.0 0.19 0.0944 0.4804 3093830 BCB03_000289 Cc1ccc(cc1)S(=O)(=O)N2CC(=CCC2c3ccccc3)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O17 compound treatment 363000.0 -101000.0 -0.86 433220.0 -35700.0 -0.3 -0.8245 -0.9015 3092772 BCB03_000290 COC(=O)c1cccc(c1)[C@@H]2C/C(=C\C(=O)OC(C)C)/O[C@@H](O2)c3cccc(c3)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O18 compound treatment 411220.0 -53200.0 -0.45 451360.0 -17600.0 -0.15 -0.4256 -0.893 3000760 BCB03_000291 Cc1ccc(cc1)[C@@H]2CC=C([C@@H](N2S(=O)(=O)c3ccc(C)cc3)c4ccccc4)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O19 compound treatment 440170.0 -24300.0 -0.21 407710.0 -61200.0 -0.52 -0.5133 -0.9182 3000977 BCB03_000292 CC(C)OC(=O)/C=C\1/C[C@H](O[C@H](O1)c2ccc(C#N)cc2)c3ccc(C#N)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O20 compound treatment 437140.0 -27300.0 -0.23 424350.0 -44600.0 -0.38 -0.4317 -0.9725 3093833 BCB03_000293 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O21 compound treatment 415650.0 -48800.0 -0.41 384800.0 -84200.0 -0.71 -0.7982 -0.9667 3092782 BCB03_000294 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2ccc(cc2)C(F)(F)F)c3ccc(cc3)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O22 compound treatment 462570.0 -1860.0 -0.02 432930.0 -36000.0 -0.31 -0.2273 -0.7427 3093834 BCB03_000295 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(C#N)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O23 compound treatment 392210.0 -72200.0 -0.61 389800.0 -79200.0 -0.67 -0.9093 -0.999 3092786 BCB03_000296 CC(C)OC(=O)/C=C/1\C[C@H](O[C@H](O1)c2cccc(c2)C(F)(F)F)c3cccc(c3)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 O24 compound treatment 330520.0 -134000.0 -1.14 387810.0 -81100.0 -0.69 -1.2923 -0.9709 3093844 BCB03_000297 Cc1ccc(cc1)S(=O)(=O)N2[C@@H](CC=C([C@@H]2c3ccccc3)C(=O)O)c4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P01 compound treatment 300320.0 -164000.0 -1.4 309710.0 -159000.0 -1.35 -1.9424 -0.9999 3071725 BCB03_000298 COC(=O)[C@H](Cc1ccc(O)cc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P02 compound treatment 277720.0 -187000.0 -1.59 331910.0 -137000.0 -1.16 -1.9452 -0.9882 3188381 BCB03_000299 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)c3ccc(CO)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P03 compound treatment 359430.0 -105000.0 -0.89 310180.0 -159000.0 -1.35 -1.584 -0.9801 3188399 BCB03_000300 COC(=O)[C@H](Cc1ccc(O)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P04 compound treatment 273690.0 -191000.0 -1.62 311450.0 -158000.0 -1.34 -2.0922 -0.9953 3070118 BCB03_000301 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)CCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P05 compound treatment 309840.0 -155000.0 -1.32 336960.0 -132000.0 -1.12 -1.7217 -0.9968 3188400 BCB03_000302 COC(=O)[C@H](Cc1ccc(OCC#C)cc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P06 compound treatment 257000.0 -207000.0 -1.76 279630.0 -189000.0 -1.61 -2.3834 -0.9989 3070119 BCB03_000303 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cccc(OC(F)(F)F)c3)CCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P07 compound treatment 281670.0 -183000.0 -1.55 278340.0 -191000.0 -1.62 -2.2428 -0.9998 3188401 BCB03_000304 Oc1ccc(C[C@@H]2N(CC#C)[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P08 compound treatment 144660.0 -320000.0 -2.72 176730.0 -292000.0 -2.48 -3.6764 -0.9989 3188385 BCB03_000305 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cccc(OC(F)(F)F)c2)c3ccc(CN4CCCC4)cc3)CCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P09 compound treatment 278330.0 -186000.0 -1.58 314350.0 -155000.0 -1.31 -2.0469 -0.9956 3188402 BCB03_000306 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccc(OCC#C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P10 compound treatment 227490.0 -237000.0 -2.02 214610.0 -254000.0 -2.16 -2.951 -0.9994 3188386 BCB03_000307 NC(=O)N1C(=O)C2C(C3C(N(Cc4cccc(OC(F)(F)F)c4)C2C=C3c5ccc(CO)cc5)c6cccs6)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P11 mock treatment 346900.0 -118000.0 -1.0 340890.0 -128000.0 -1.09 -1.4752 -0.9991 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P12 mock treatment 412490.0 -51900.0 -0.44 341480.0 -127000.0 -1.08 -1.0771 -0.922 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P13 compound treatment 254120.0 -210000.0 -1.79 248210.0 -221000.0 -1.87 -2.5892 -0.9997 3070937 BCB03_000308 COC(=O)[C@H](Cc1ccc(O)cc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P14 compound treatment 248430.0 -216000.0 -1.84 231600.0 -237000.0 -2.01 -2.7231 -0.999 3188387 BCB03_000309 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1C)CCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P15 compound treatment 193150.0 -271000.0 -2.31 238040.0 -231000.0 -1.96 -3.017 -0.9967 3188528 BCB03_000310 Oc1ccc(C[C@@H]2N3CC4=CCCC=C[C@@H]4[C@H]3[C@@H](Cc5ccccc5)OC2=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P16 compound treatment 271380.0 -193000.0 -1.64 298660.0 -170000.0 -1.44 -2.1828 -0.998 3070122 BCB03_000311 COP(=O)(OC)/N=C\1/CC(=CC(N1C)c2ccc(CN3CCCC3)cc2)CCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P17 compound treatment 350190.0 -114000.0 -0.97 286520.0 -182000.0 -1.55 -1.7815 -0.9749 3188529 BCB03_000312 COC(=O)[C@H](Cc1ccccc1)N[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P18 compound treatment 167080.0 -297000.0 -2.53 174250.0 -295000.0 -2.5 -3.5564 -1.0 3188390 BCB03_000313 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3cc4OCOc4cc3Br)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P19 compound treatment 285370.0 -179000.0 -1.52 239450.0 -230000.0 -1.95 -2.4538 -0.9926 3188530 BCB03_000314 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@@H](/C=C/C2CC2)[C@H](O)Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P20 compound treatment 200750.0 -264000.0 -2.24 172530.0 -296000.0 -2.51 -3.3642 -0.9984 3188503 BCB03_000315 COP(=O)(OC)/N=C\1/CC(=CC(C)N1Cc2cccc(OC(F)(F)F)c2)CCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P21 compound treatment 49570.0 -415000.0 -3.53 64970.0 -404000.0 -3.43 -4.9188 -0.9999 3070940 BCB03_000316 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@H]2[C@H](O)Cc3ccccc3)/C=C/C4CC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P22 compound treatment 220110.0 -244000.0 -2.08 253360.0 -216000.0 -1.83 -2.7629 -0.998 3070124 BCB03_000317 COP(=O)(OC)/N=C\1/CC(=CC(N1Cc2cc3OCOc3cc2Br)c4ccc(CN5CCCC5)cc4)CCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P23 compound treatment 233790.0 -231000.0 -1.96 230480.0 -238000.0 -2.02 -2.8179 -0.9999 3188533 BCB03_000318 O=C1O[C@@H](Cc2ccccc2)[C@@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2281 P24 compound treatment 109940.0 -354000.0 -3.02 96690.0 -372000.0 -3.16 -4.3654 -0.9997 3188506 BCB03_000319 COP(=O)(OC)/N=C\1/CC(=CC(C2CC2)N1Cc3sc4ccccc4c3Cl)c5ccc(CO)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A01 compound treatment 437940.0 -13900.0 -0.12 379920.0 -48900.0 -0.41 -0.3768 -0.8734 3188507 BCB03_000320 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(o3)c4ccc(Cl)c(Cl)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A02 compound treatment 424800.0 -27000.0 -0.23 437230.0 8390.0 0.07 -0.1121 -0.4662 3071186 BCB03_000321 COc1ccc(cc1)[C@H]2OC[C@@H]3CCC(=O)N23 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A03 compound treatment 171000.0 -281000.0 -2.39 469120.0 40300.0 0.34 -1.4476 -0.5999 3070126 BCB03_000322 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A04 compound treatment 522110.0 70300.0 0.6 478900.0 50100.0 0.42 0.7232 0.9859 3071252 BCB03_000323 COc1cccc(C[C@H]2C[C@@H](CO)NC2=O)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A05 compound treatment 297190.0 -155000.0 -1.32 449710.0 20900.0 0.18 -0.8049 -0.6065 3070127 BCB03_000324 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A06 compound treatment 409080.0 -42700.0 -0.36 461600.0 32800.0 0.28 -0.0605 -0.1322 3071181 BCB03_000325 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@]4(O[C@@]23[C@H]5[C@@H]4C(=O)N(C)C5=O)C(=O)C)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A07 compound treatment 400730.0 -51100.0 -0.43 265890.0 -163000.0 -1.38 -1.2846 -0.8866 3070128 BCB03_000326 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3CO[Si](C(C)C)(C(C)C)c31 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A08 compound treatment 410470.0 -41300.0 -0.35 450720.0 21900.0 0.19 -0.1174 -0.2952 3189172 BCB03_000327 COc1cccc(C[C@H]2C[C@@H](CO[Si](C(C)C)(C(C)C)C(C)C)N3C(=O)[C@@]4(O[C@]23[C@@H]5[C@H]4C(=O)N(C)C5=O)C(=O)C)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A09 compound treatment 499880.0 48100.0 0.41 440740.0 11900.0 0.1 0.3606 0.8559 3070129 BCB03_000328 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C3CC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A10 compound treatment 483200.0 31400.0 0.27 316280.0 -113000.0 -0.95 -0.4863 -0.4904 3071185 BCB03_000329 COc1ccc(cc1)[C@H]2OC[C@@H]3CC4(CC=CC4)C(=O)N23 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A11 compound treatment 353190.0 -98600.0 -0.84 393450.0 -35400.0 -0.3 -0.8055 -0.904 3188514 BCB03_000330 CCCCCCc1nc(c2ccc(o2)c3ccc(Cl)c(Cl)c3)c(C)c4CO[Si](C(C)C)(C(C)C)c41 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A12 compound treatment 297940.0 -154000.0 -1.31 415300.0 -13500.0 -0.11 -1.0068 -0.7662 3189173 BCB03_000331 NC(=N)NCc1cn(CCc2c[nH]c3ccccc23)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A13 mock treatment 378260.0 -73500.0 -0.63 297130.0 -132000.0 -1.12 -1.2324 -0.9624 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A14 mock treatment 490040.0 38200.0 0.33 410630.0 -18200.0 -0.15 0.1208 0.3354 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A15 compound treatment 370790.0 -81000.0 -0.69 442030.0 13200.0 0.11 -0.4082 -0.5847 3070178 BCB03_000332 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3cc(C)c(OC)c(C)c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A16 compound treatment 374020.0 -77800.0 -0.66 299110.0 -130000.0 -1.1 -1.246 -0.9704 3071253 BCB03_000333 COC(=O)c1c(CC[C@@H](CO)NC(=O)N(C)Cc2ccccc2)oc(C(=O)OCC=C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A17 compound treatment 488550.0 36800.0 0.31 427940.0 -901.0 -0.01 0.2157 0.6896 3070179 BCB03_000334 CCCCCCc1nc(c(C)c2CO[Si](C(C)C)(C(C)C)c21)c3ccc(OC)nc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A18 compound treatment 454580.0 2780.0 0.02 417200.0 -11600.0 -0.1 -0.0531 -0.5229 3071184 BCB03_000335 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@@H](Cc4ccccc4)C(=O)N23 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A19 compound treatment 342720.0 -109000.0 -0.93 392340.0 -36500.0 -0.31 -0.8751 -0.8946 3070180 BCB03_000336 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A20 compound treatment 358820.0 -93000.0 -0.79 455530.0 26700.0 0.23 -0.3992 -0.4852 3071183 BCB03_000337 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@H](Cc4ccccc4)C(=O)N23 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A21 compound treatment 401200.0 -50600.0 -0.43 464220.0 35400.0 0.3 -0.0922 -0.1756 3070181 BCB03_000338 CCCCCCc1nc(C2CC2)c(C)c3CO[Si](C(C)C)(C(C)C)c31 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A22 compound treatment 261850.0 -190000.0 -1.62 287690.0 -141000.0 -1.2 -1.9893 -0.9891 3189417 BCB03_000339 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(COC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A23 compound treatment 337950.0 -114000.0 -0.97 458840.0 30000.0 0.25 -0.5049 -0.5042 3188651 BCB03_000340 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 A24 compound treatment 422150.0 -29600.0 -0.25 447260.0 18400.0 0.16 -0.0679 -0.2288 3070196 BCB03_000341 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccn2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B01 compound treatment 285230.0 -167000.0 -1.42 309230.0 -120000.0 -1.01 -1.7195 -0.9866 3188662 BCB03_000342 COC(=O)[C@H](Cc1ccccc1)N2CC(=C[C@@H]2[C@@H](O)Cc3ccccc3)/C=C/C4CC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B02 compound treatment 362340.0 -89500.0 -0.76 337120.0 -91700.0 -0.78 -1.0883 -0.9999 3071724 BCB03_000343 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@]4(CO4)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B03 compound treatment 452450.0 651.0 0.01 413250.0 -15600.0 -0.13 -0.0896 -0.6769 3188663 BCB03_000344 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B04 compound treatment 373960.0 -77800.0 -0.66 378750.0 -50100.0 -0.42 -0.7687 -0.977 3071727 BCB03_000345 C[C@]12COC[C@@]2(C=C(Br)[C@@H]3C1)C(=O)[C@@]43CO4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B05 compound treatment 507610.0 55800.0 0.47 474280.0 45400.0 0.39 0.6083 0.9946 3070955 BCB03_000346 COC(=O)[C@H](Cc1ccccc1)N2CC(C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B06 compound treatment 355590.0 -96200.0 -0.82 360440.0 -68400.0 -0.58 -0.989 -0.9858 3071766 BCB03_000347 CCCCC[C@H]1OC[C@@]2(C=C(Br)[C@@H]3CC12)C(=O)[C@@]43CO4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B07 compound treatment 432890.0 -18900.0 -0.16 388250.0 -40600.0 -0.34 -0.3572 -0.9399 3188666 BCB03_000348 COC(=O)[C@H](Cc1ccccc1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B08 compound treatment 344070.0 -108000.0 -0.92 378430.0 -50400.0 -0.43 -0.9504 -0.9398 3071767 BCB03_000349 CC1(C)OC[C@@]2(C=C(Br)[C@@H]3C[C@H]12)C(=O)[C@@]43CO4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B09 compound treatment 459720.0 7920.0 0.07 374890.0 -54000.0 -0.46 -0.276 -0.5966 3188667 BCB03_000350 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4ccccc4Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B10 compound treatment 337230.0 -115000.0 -0.97 360160.0 -68700.0 -0.58 -1.1012 -0.9697 3071770 BCB03_000351 BrC1=C[C@]23COCC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B11 compound treatment 437720.0 -14100.0 -0.12 485120.0 56300.0 0.48 0.2529 0.5138 3188668 BCB03_000352 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/c2ccccc2)[C@@H](O)Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B12 compound treatment 7960.0 -444000.0 -3.78 9190.0 -420000.0 -3.56 -5.1871 -0.9996 3071774 BCB03_000353 C=CCC1=C[C@H]2[C@H]([C@H]3C=C[C@]2(CC=C)C(=O)[C@@]43CO4)[C@@]5(CO5)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B13 mock treatment 437040.0 -14800.0 -0.13 446170.0 17300.0 0.15 0.0152 0.0784 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B14 mock treatment 440360.0 -11400.0 -0.1 473720.0 44900.0 0.38 0.2004 0.51 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B15 compound treatment 296560.0 -155000.0 -1.32 386570.0 -42300.0 -0.36 -1.1874 -0.8677 3070996 BCB03_000354 O[C@@H](Cc1ccccc1)[C@@H](/C=C/c2ccccc2)N(CC#C)Cc3ccccc3Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B16 compound treatment 4580.0 -447000.0 -3.8 4830.0 -424000.0 -3.6 -5.2336 -0.9996 3188527 BCB03_000355 CC1=C[C@]2(CO)C(=O)[C@]3(CO3)[C@H]1[C@@H]4[C@@]5(CO5)C(=O)C(=C[C@@]42C)CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B17 compound treatment 436370.0 -15400.0 -0.13 280190.0 -149000.0 -1.26 -0.9845 -0.7765 3070997 BCB03_000356 CCCC/C=C/[C@H]([C@@H](O)Cc1ccccc1)N(CC#Cc2ccccc2)Cc3ccccc3Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B18 compound treatment 289670.0 -162000.0 -1.38 277710.0 -151000.0 -1.28 -1.8818 -0.9993 3070938 BCB03_000357 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B19 compound treatment 455400.0 3600.0 0.03 406080.0 -22800.0 -0.19 -0.1149 -0.5876 3071055 BCB03_000358 CCC#CCN(Cc1ccccc1Br)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B20 compound treatment 362720.0 -89100.0 -0.76 419860.0 -8980.0 -0.08 -0.5897 -0.7743 3070939 BCB03_000359 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)c4ccccc4)C2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B21 compound treatment 263070.0 -189000.0 -1.61 253170.0 -176000.0 -1.49 -2.189 -0.9993 3188794 BCB03_000360 O[C@@H](Cc1ccccc1)[C@H](NCc2cccc(Cl)c2)/C=C/C3CC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B22 compound treatment 400410.0 -51400.0 -0.44 370130.0 -58700.0 -0.5 -0.6613 -0.9979 3188531 BCB03_000361 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Oc4ccccc4)cc3)C2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B23 compound treatment 445530.0 -6270.0 -0.05 456960.0 28100.0 0.24 0.131 0.5358 3188796 BCB03_000362 O[C@@H](Cc1ccccc1)[C@@H](/C=C/C2CC2)N(CC#Cc3ccccc3)Cc4cccc(Cl)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 B24 compound treatment 342100.0 -110000.0 -0.93 359860.0 -69000.0 -0.59 -1.0737 -0.9747 3188532 BCB03_000363 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(cc3)C(F)(F)F)C2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C01 compound treatment 467910.0 16100.0 0.14 437300.0 8460.0 0.07 0.1477 0.9544 3070235 BCB03_000364 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4cc(C)c(OC)c(C)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C02 compound treatment 508860.0 57100.0 0.49 415600.0 -13200.0 -0.11 0.2638 0.5295 3189039 BCB03_000365 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C03 compound treatment 380640.0 -71200.0 -0.61 444320.0 15500.0 0.13 -0.3352 -0.5412 3070236 BCB03_000366 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)c4ccc(OC)nc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C04 compound treatment 445010.0 -6790.0 -0.06 424480.0 -4360.0 -0.04 -0.067 -0.9768 3070086 BCB03_000367 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(CCCNC(=N)N)nn2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C05 compound treatment 311050.0 -141000.0 -1.2 395040.0 -33800.0 -0.29 -1.0494 -0.8523 3188655 BCB03_000368 CCCCCCc1nc(Cc2cc(OC)c(OC)c(OC)c2)cc3[C@@H](O[Si](C(C)C)(C(C)C)c31)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C06 compound treatment 357130.0 -94700.0 -0.81 350410.0 -78400.0 -0.67 -1.0399 -0.9955 3070191 BCB03_000369 N[C@@H](Cc1ccccc1)C(=O)NCc2cn(Cc3ccccc3)nn2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C07 compound treatment 420880.0 -30900.0 -0.26 398990.0 -29900.0 -0.25 -0.365 -0.9998 3188656 BCB03_000370 CCCCCCc1nc(cc2[C@@H](O[Si](C(C)C)(C(C)C)c21)c3ccccc3)C4CC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C08 compound treatment 453120.0 1320.0 0.01 457920.0 29100.0 0.25 0.1824 0.7386 3071180 BCB03_000371 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)c3ccccn3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C09 compound treatment 426450.0 -25300.0 -0.22 404240.0 -24600.0 -0.21 -0.3 -0.9999 3188772 BCB03_000372 CCCCCCc1nc(CCCc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCCCCC)n2)c4ccccc4)cc5[C@@H](O[Si](C(C)C)(C(C)C)c51)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C10 compound treatment 438790.0 -13000.0 -0.11 424160.0 -4680.0 -0.04 -0.1063 -0.9044 3070134 BCB03_000373 OC(=O)[C@H](Cc1ccccc1)n2cc(nn2)C3(O)CCCCC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C11 mock treatment 453510.0 1710.0 0.01 436000.0 7160.0 0.06 0.0532 0.8525 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C12 mock treatment 421230.0 -30600.0 -0.26 388520.0 -40300.0 -0.34 -0.4257 -0.9909 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C13 compound treatment 436250.0 -15500.0 -0.13 391260.0 -37600.0 -0.32 -0.319 -0.9241 3070242 BCB03_000374 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C14 compound treatment 441140.0 -10700.0 -0.09 357200.0 -71600.0 -0.61 -0.4938 -0.8037 3070089 BCB03_000375 CC(C)[C@@H](C(=O)O)n1cc(nn1)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C15 mock treatment 419800.0 -32000.0 -0.27 411130.0 -17700.0 -0.15 -0.2987 -0.9608 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C16 mock treatment 342340.0 -109000.0 -0.93 360020.0 -68800.0 -0.58 -1.0713 -0.9747 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C17 compound treatment 423130.0 -28700.0 -0.24 408730.0 -20100.0 -0.17 -0.2931 -0.9847 3070245 BCB03_000376 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C18 compound treatment 388080.0 -63700.0 -0.54 348970.0 -79900.0 -0.68 -0.8624 -0.9939 3071179 BCB03_000377 CC(C)[C@@H](C(=O)O)n1cc(nn1)C2(O)CCCCC2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C19 compound treatment 421370.0 -30400.0 -0.26 328930.0 -99900.0 -0.85 -0.7823 -0.8828 3070527 BCB03_000378 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)cc(OC)c1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C20 compound treatment 394350.0 -57400.0 -0.49 383480.0 -45400.0 -0.38 -0.6177 -0.993 3414058 BCB03_000379 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C21 compound treatment 331060.0 -121000.0 -1.03 396130.0 -32700.0 -0.28 -0.9225 -0.867 3070530 BCB03_000380 CC(C)[Si]1(OCc2cc(nc(c21)c3ccccc3)C4CC4)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C22 compound treatment 437990.0 -13800.0 -0.12 416110.0 -12700.0 -0.11 -0.1594 -0.9991 3189555 BCB03_000381 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C23 compound treatment 345200.0 -107000.0 -0.91 299610.0 -129000.0 -1.1 -1.4164 -0.9956 3070081 BCB03_000382 CC(C)[Si]1(OCc2c1c(nc(c3ccc(o3)c4ccc(Cl)c(Cl)c4)c2C)c5ccccc5)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 C24 compound treatment 302830.0 -149000.0 -1.27 226560.0 -202000.0 -1.72 -2.1095 -0.9889 3189558 BCB03_000383 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D01 compound treatment 433220.0 -18600.0 -0.16 408880.0 -20000.0 -0.17 -0.2315 -0.9994 3071060 BCB03_000384 O[C@@H](Cc1ccccc1)[C@H](NCc2ccccc2Br)/C=C/c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D02 compound treatment 273810.0 -178000.0 -1.51 233490.0 -195000.0 -1.66 -2.2425 -0.999 3070941 BCB03_000385 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4[nH]ccc4c3)C2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D03 compound treatment 369550.0 -82200.0 -0.7 264480.0 -164000.0 -1.39 -1.4806 -0.9492 3188797 BCB03_000386 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC=C3CN2Cc4cccc(Cl)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D04 compound treatment 328240.0 -124000.0 -1.05 293930.0 -135000.0 -1.14 -1.5525 -0.9991 3070942 BCB03_000387 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3cccc4[nH]ccc34)C2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D05 compound treatment 510890.0 59100.0 0.5 484340.0 55500.0 0.47 0.6884 0.9995 3188798 BCB03_000388 COC1(C)CN(Cc2ccccc2Br)[C@H](/C=C/c3ccccc3)[C@H](Cc4ccccc4)O1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D06 compound treatment 390430.0 -61400.0 -0.52 465360.0 36500.0 0.31 -0.1501 -0.2473 3070943 BCB03_000389 CC(C)Oc1ccc(cc1)C(=O)N2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D07 compound treatment 368720.0 -83100.0 -0.71 359200.0 -69600.0 -0.59 -0.9175 -0.996 3188799 BCB03_000390 CN1C(=O)C2C3[C@H]([C@@H](O)Cc4ccccc4)N(Cc5cccc(Cl)c5)CC3=CC(C6CC6)C2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D08 compound treatment 467840.0 16000.0 0.14 385950.0 -42900.0 -0.36 -0.1608 -0.4137 3188537 BCB03_000391 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc(Br)cc3)C2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D09 compound treatment 476510.0 24700.0 0.21 401010.0 -27800.0 -0.24 -0.0183 -0.0578 3071066 BCB03_000392 O[C@@H](Cc1ccccc1)[C@H](N(CC#C)CC2=CCCCC2)c3ccccc3Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D10 compound treatment 323700.0 -128000.0 -1.09 285170.0 -144000.0 -1.22 -1.6324 -0.9984 3070952 BCB03_000393 CC(C)Cc1ccc(CN2CC[C@@H](N)C2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D11 mock treatment 467690.0 15900.0 0.14 477810.0 49000.0 0.42 0.3893 0.8912 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D12 mock treatment 412890.0 -38900.0 -0.33 465640.0 36800.0 0.31 -0.0133 -0.0293 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D13 compound treatment 453460.0 1660.0 0.01 471620.0 42800.0 0.36 0.2666 0.7341 3071068 BCB03_000394 O=C(Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4ccccc4)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D14 compound treatment 297960.0 -154000.0 -1.31 298720.0 -130000.0 -1.1 -1.7059 -0.9964 3070953 BCB03_000395 CC(C)Cc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3ccccc3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D15 mock treatment 481990.0 30200.0 0.26 357850.0 -71000.0 -0.6 -0.2442 -0.373 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D16 mock treatment 441500.0 -10300.0 -0.09 456040.0 27200.0 0.23 0.1012 0.41 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D17 compound treatment 253470.0 -198000.0 -1.69 218660.0 -210000.0 -1.78 -2.4538 -0.9996 3071112 BCB03_000396 O[C@@H](Cc1ccccc1)[C@H]2C3C=CCCC(=C3CN2Cc4cccc(Cl)c4)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D18 compound treatment 408050.0 -43700.0 -0.37 285130.0 -144000.0 -1.22 -1.1252 -0.8828 3070954 BCB03_000397 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)c3ccccc3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D19 compound treatment 278720.0 -173000.0 -1.47 349340.0 -79500.0 -0.67 -1.518 -0.9373 3188804 BCB03_000398 Clc1cccc(CN2CC3=CCCC=CC3[C@@H]2[C@H](Cc4ccccc4)OC(=O)C=C)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D20 compound treatment 65160.0 -387000.0 -3.29 18560.0 -410000.0 -3.48 -4.7868 -0.9996 3188664 BCB03_000399 CC(C)Cc1ccc(CN2CC[C@H](C2)NC(=O)Nc3ccccc3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D21 compound treatment 104700.0 -347000.0 -2.95 81480.0 -347000.0 -2.95 -4.1715 -1.0 3071454 BCB03_000400 CCC1=C2CN(Cc3ccccc3Br)[C@@H]([C@@H](O)Cc4ccccc4)C2C=CCC1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D22 compound treatment 239490.0 -212000.0 -1.81 234680.0 -194000.0 -1.65 -2.4418 -0.9989 3188665 BCB03_000401 CC(C)Oc1ccc(CN2CC[C@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D23 compound treatment 260110.0 -192000.0 -1.63 346480.0 -82400.0 -0.7 -1.6471 -0.9284 3071455 BCB03_000402 CCC1=C2CN(Cc3ccccc3)[C@H](C2C=CCC1)C(=O)Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 D24 compound treatment 300610.0 -151000.0 -1.29 234490.0 -194000.0 -1.65 -2.0752 -0.9925 3070994 BCB03_000403 CC(C)Oc1ccc(CN2CC[C@@H](C2)NS(=O)(=O)c3cc(F)ccc3C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E01 mock treatment 469980.0 18200.0 0.15 433180.0 4340.0 0.04 0.1354 0.8516 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E02 mock treatment 471300.0 19500.0 0.17 436110.0 7270.0 0.06 0.1609 0.9092 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E03 compound treatment 462670.0 10900.0 0.09 439140.0 10300.0 0.09 0.1272 0.9996 3189040 BCB03_000404 COc1c(C)cc(cc1C)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E04 compound treatment 519410.0 67600.0 0.58 440350.0 11500.0 0.1 0.4758 0.8155 3189560 BCB03_000405 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H]5CCCN5C2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E05 compound treatment 483170.0 31400.0 0.27 433020.0 4180.0 0.04 0.2138 0.7941 3189041 BCB03_000406 COc1ccc(cn1)c2nc(c3c(CO[Si]3(C(C)C)C(C)C)c2C)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E06 compound treatment 472000.0 20200.0 0.17 404000.0 -24800.0 -0.21 -0.0275 -0.1011 3189559 BCB03_000407 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cnnn4C[C@@H]5CCCN5C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E07 compound treatment 470630.0 18800.0 0.16 467230.0 38400.0 0.33 0.3435 0.9466 3189042 BCB03_000408 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E08 compound treatment 485170.0 33400.0 0.28 362580.0 -66300.0 -0.56 -0.1967 -0.3124 3189043 BCB03_000409 N[C@@H](Cc1ccccc1)Cn2cc(nn2)C3(O)CCCCC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E09 mock treatment 491680.0 39900.0 0.34 455130.0 26300.0 0.22 0.3976 0.9793 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E10 mock treatment 484800.0 33000.0 0.28 439280.0 10400.0 0.09 0.2611 0.8871 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E11 compound treatment 303620.0 -148000.0 -1.26 467280.0 38400.0 0.33 -0.6608 -0.5075 3070137 BCB03_000410 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E12 compound treatment 266280.0 -186000.0 -1.58 291870.0 -137000.0 -1.16 -1.9376 -0.9887 3070143 BCB03_000411 N[C@@H](Cc1ccccc1)Cn2cc(nn2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E13 compound treatment 489120.0 37300.0 0.32 365000.0 -63800.0 -0.54 -0.1584 -0.2524 3189044 BCB03_000412 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(n2)c4ccccc4)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E14 compound treatment 351280.0 -101000.0 -0.86 395430.0 -33400.0 -0.28 -0.8051 -0.8937 3189695 BCB03_000413 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cn(C[C@H](Cc4ccccc4)NC2=O)nn3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E15 compound treatment 414670.0 -37100.0 -0.32 440680.0 11800.0 0.1 -0.1523 -0.4596 3189045 BCB03_000414 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccccc3)C4CC4)c5ccccc5)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E16 compound treatment 468580.0 16800.0 0.14 415570.0 -13300.0 -0.11 0.0213 0.1174 3071393 BCB03_000415 COC(=O)c1nc2oc1CC[C@@H](CO)NC(=O)N(C)Cc3cnnn3C[C@H](Cc4ccccc4)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E17 mock treatment 377410.0 -74400.0 -0.63 474680.0 45800.0 0.39 -0.1725 -0.2323 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E18 mock treatment 431580.0 -20200.0 -0.17 467320.0 38500.0 0.33 0.1092 0.2959 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E19 compound treatment 336230.0 -116000.0 -0.98 322650.0 -106000.0 -0.9 -1.3322 -0.999 3189046 BCB03_000416 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E20 compound treatment 326240.0 -126000.0 -1.07 462620.0 33800.0 0.29 -0.5527 -0.4998 3071396 BCB03_000417 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](C)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E21 compound treatment 424890.0 -26900.0 -0.23 441640.0 12800.0 0.11 -0.0851 -0.3359 3189047 BCB03_000418 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E22 compound treatment 453640.0 1840.0 0.02 361410.0 -67400.0 -0.57 -0.3934 -0.6875 3187595 BCB03_000419 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](NC2=O)C(C)C)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E23 compound treatment 382610.0 -69200.0 -0.59 391720.0 -37100.0 -0.31 -0.6389 -0.957 3189169 BCB03_000420 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 E24 compound treatment 474360.0 22600.0 0.19 306500.0 -122000.0 -1.04 -0.5981 -0.5667 3187594 BCB03_000421 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F01 mock treatment 513850.0 62100.0 0.53 383540.0 -45300.0 -0.38 0.1015 0.1555 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F02 mock treatment 445140.0 -6660.0 -0.06 424370.0 -4470.0 -0.04 -0.0669 -0.981 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F03 compound treatment 429690.0 -22100.0 -0.19 251610.0 -177000.0 -1.5 -1.1961 -0.7894 3071456 BCB03_000422 C/C=C\[C@@H](NCc1ccccc1Br)[C@@H](O)Cc2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F04 compound treatment 393350.0 -58400.0 -0.5 265460.0 -163000.0 -1.39 -1.3316 -0.9044 3070995 BCB03_000423 Cc1ccc(F)cc1S(=O)(=O)N[C@@H]2CCN(Cc3ccc4OCOc4c3)C2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F05 compound treatment 443170.0 -8630.0 -0.07 424230.0 -4610.0 -0.04 -0.0796 -0.9566 3071457 BCB03_000424 CC(=CCN[C@H](CO)c1ccccc1)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F06 compound treatment 461690.0 9890.0 0.08 374620.0 -54200.0 -0.46 -0.2657 -0.5683 2133134 BCB03_000425 CCCCC(=O)N(CCN1CCOCC1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F07 compound treatment 469790.0 18000.0 0.15 449010.0 20200.0 0.17 0.2292 0.9985 3071458 BCB03_000426 CC(=CCN(CC#C)[C@H](CO)c1ccccc1)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F08 compound treatment 440000.0 -11800.0 -0.1 429780.0 939.0 0.01 -0.0653 -0.649 2133147 BCB03_000427 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCCO4)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F09 mock treatment 312840.0 -139000.0 -1.18 349500.0 -79300.0 -0.67 -1.3118 -0.9643 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F10 mock treatment 443090.0 -8710.0 -0.07 441680.0 12800.0 0.11 0.0246 0.1869 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F11 compound treatment 200640.0 -251000.0 -2.14 202210.0 -227000.0 -1.92 -2.8702 -0.9986 3187737 BCB03_000428 CC(=CCN(CC#Cc1ccccc1)[C@H](CO)c2ccccc2)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F12 compound treatment 337600.0 -114000.0 -0.97 358200.0 -70600.0 -0.6 -1.1107 -0.973 3188671 BCB03_000429 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCCc3c[nH]c4ccccc34)[C@@H]2O)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F13 compound treatment 426770.0 -25000.0 -0.21 324430.0 -104000.0 -0.89 -0.7768 -0.8528 3071460 BCB03_000430 O=C1OC[C@@H](c2ccccc2)n3cc(/C=C/c4ccccc4)cc13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F14 compound treatment 342370.0 -109000.0 -0.93 438370.0 9530.0 0.08 -0.6011 -0.6433 2129060 BCB03_000431 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCC3CCCCC3)[C@@H]2O)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F15 compound treatment 396010.0 -55800.0 -0.47 330330.0 -98500.0 -0.84 -0.9265 -0.9641 3071461 BCB03_000432 CC(=C)C/1CN([C@H](CO)c2ccccc2)C(=O)\C1=C/c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F16 compound treatment 401600.0 -50200.0 -0.43 319420.0 -109000.0 -0.93 -0.9583 -0.9379 2129057 BCB03_000433 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC[C@@H]3CCCO3)[C@@H]2O)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F17 mock treatment 454460.0 2660.0 0.02 502280.0 73400.0 0.62 0.4565 0.7323 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F18 mock treatment 344910.0 -107000.0 -0.91 433380.0 4540.0 0.04 -0.6158 -0.6766 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F19 compound treatment 297450.0 -154000.0 -1.31 363940.0 -64900.0 -0.55 -1.3178 -0.9255 3071462 BCB03_000434 OCC(/C=C/c1ccccc1)N(CC#C)C(C(=O)O)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F20 compound treatment 181850.0 -270000.0 -2.3 178800.0 -250000.0 -2.12 -3.1237 -0.9992 2129061 BCB03_000435 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NC3CCCCCC3)[C@@H]2O)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F21 compound treatment 310470.0 -141000.0 -1.2 329280.0 -99600.0 -0.84 -1.4474 -0.9851 3071463 BCB03_000436 C/C=C/CN([C@H](CO[Si](C)(C)C(C)(C)C)c1ccccc1)C(=O)C#Cc2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F22 compound treatment 394330.0 -57500.0 -0.49 333920.0 -94900.0 -0.81 -0.9151 -0.9714 2129067 BCB03_000437 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccccc3F)[C@@H]2O)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F23 compound treatment 442720.0 -9080.0 -0.08 397370.0 -31500.0 -0.27 -0.2434 -0.8758 3071464 BCB03_000438 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 F24 compound treatment 225990.0 -226000.0 -1.92 230480.0 -198000.0 -1.68 -2.5482 -0.9978 2129068 BCB03_000439 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H](NCc3ccc(F)cc3)[C@@H]2O)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G01 compound treatment 447080.0 -4720.0 -0.04 380960.0 -47900.0 -0.41 -0.3156 -0.7732 3189170 BCB03_000440 COc1cc(Cc2cc3CO[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)cc(OC)c1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G02 compound treatment 464840.0 13000.0 0.11 453480.0 24600.0 0.21 0.2262 0.9561 3187594 BCB03_000441 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G03 mock treatment 523740.0 71900.0 0.61 406080.0 -22800.0 -0.19 0.2962 0.4616 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G04 mock treatment 398240.0 -53600.0 -0.46 429540.0 699.0 0.01 -0.318 -0.6978 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G05 compound treatment 458250.0 6450.0 0.05 520250.0 91400.0 0.78 0.5871 0.7553 3189171 BCB03_000442 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G06 compound treatment 478880.0 27100.0 0.23 475790.0 46900.0 0.4 0.4445 0.9661 3187597 BCB03_000443 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](NC2=O)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G07 compound treatment 474240.0 22400.0 0.19 444690.0 15800.0 0.13 0.2301 0.9853 3071182 BCB03_000444 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G08 compound treatment 503380.0 51600.0 0.44 511060.0 82200.0 0.7 0.8035 0.9751 3189696 BCB03_000445 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G09 compound treatment 440280.0 -11500.0 -0.1 380540.0 -48300.0 -0.41 -0.359 -0.8522 3189286 BCB03_000446 CC(C)[Si]1(O[C@H](c2cc(nc(CCc3ccccc3)c21)c4ccc(o4)c5ccc(Cl)c(Cl)c5)c6ccccc6)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G10 compound treatment 534480.0 82700.0 0.7 406320.0 -22500.0 -0.19 0.3623 0.4971 3187593 BCB03_000447 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)NC3(CCCCC3)c4cnnn4C[C@@H](Cc5ccccc5)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G11 compound treatment 390340.0 -61500.0 -0.52 406400.0 -22400.0 -0.19 -0.5043 -0.9064 3189287 BCB03_000448 COc1c(C)cc(cc1C)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G12 compound treatment 467490.0 15700.0 0.13 355330.0 -73500.0 -0.62 -0.3465 -0.5434 3414059 BCB03_000449 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(Cc5ccccc5)C2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G13 compound treatment 399360.0 -52400.0 -0.45 415390.0 -13500.0 -0.11 -0.3961 -0.8603 3189288 BCB03_000450 COc1ccc(cn1)c2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G14 compound treatment 458130.0 6330.0 0.05 437140.0 8300.0 0.07 0.0879 0.9913 3414060 BCB03_000451 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(nn4)C5(CCCCC5)NC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G15 compound treatment 275840.0 -176000.0 -1.5 229440.0 -199000.0 -1.69 -2.2545 -0.9981 3189289 BCB03_000452 COc1cc(Cc2cc3[C@@H](O[Si](C(C)C)(C(C)C)c3c(CCc4ccccc4)n2)c5ccccc5)cc(OC)c1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G16 compound treatment 460230.0 8430.0 0.07 358000.0 -70800.0 -0.6 -0.3742 -0.6183 3189561 BCB03_000453 CN1Cc2cn(C[C@H](Cc3ccccc3)NC(=O)c4cc(c(CC[C@@H](CO)NC1=O)o4)S(=O)(=O)c5ccc(C)cc5)nn2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G17 compound treatment 307730.0 -144000.0 -1.23 393190.0 -35700.0 -0.3 -1.0805 -0.8559 3189171 BCB03_000454 CC(C)[Si]1(OCc2cc(nc(CCc3ccccc3)c21)C4CC4)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G18 compound treatment 335270.0 -117000.0 -0.99 411490.0 -17400.0 -0.15 -0.8051 -0.8033 3189290 BCB03_000455 COc1ccc(cc1)[C@H]2OC[C@@H]3CC(CC=C)(CC=C)C(=O)N23 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G19 mock treatment 349020.0 -103000.0 -0.87 402680.0 -26200.0 -0.22 -0.7752 -0.8593 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G20 mock treatment 395000.0 -56800.0 -0.48 414800.0 -14000.0 -0.12 -0.4259 -0.8558 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G21 compound treatment 346610.0 -105000.0 -0.89 380080.0 -48800.0 -0.41 -0.9252 -0.9385 3071182 BCB03_000456 CC(C)[Si]1(OCc2cc(CCCc3cc4CO[Si](C(C)C)(C(C)C)c4c(CCc5ccccc5)n3)nc(CCc6ccccc6)c21)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G22 compound treatment 243480.0 -208000.0 -1.77 312290.0 -117000.0 -0.99 -1.9523 -0.962 3071255 BCB03_000457 NC(=N)NCC#C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G23 compound treatment 401310.0 -50500.0 -0.43 349360.0 -79500.0 -0.67 -0.7805 -0.9763 3188910 BCB03_000458 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)c5ccc(o5)c6ccc(Cl)c(Cl)c6)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 G24 compound treatment 439690.0 -12100.0 -0.1 300290.0 -129000.0 -1.09 -0.8439 -0.7705 3189419 BCB03_000459 OC(=O)CCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H01 compound treatment 381280.0 -70500.0 -0.6 245540.0 -183000.0 -1.55 -1.5237 -0.9142 3071464 BCB03_000460 O=C1OC[C@H](N(CC#C)C1/C=C/c2ccccc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H02 compound treatment 370930.0 -80900.0 -0.69 359370.0 -69500.0 -0.59 -0.9032 -0.997 3071064 BCB03_000461 CCCC(=O)N(CCc1c[nH]c2ccccc12)[C@@H]3CC(=C[C@H](Oc4c(I)cc(CO)cc4OC)[C@H]3O)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H03 mock treatment 477140.0 25300.0 0.22 271100.0 -158000.0 -1.34 -0.7937 -0.5856 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H04 mock treatment 325080.0 -127000.0 -1.08 438900.0 10100.0 0.09 -0.7019 -0.6491 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H05 compound treatment 499060.0 47300.0 0.4 431870.0 3030.0 0.03 0.3025 0.7508 3071517 BCB03_000462 CC(=C)C1C(=C)CN([C@H](CO)c2ccccc2)C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H06 compound treatment 515110.0 63300.0 0.54 475610.0 46800.0 0.4 0.6614 0.9887 2133032 BCB03_000463 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4ccc(cc4)C(F)(F)F)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H07 compound treatment 529510.0 77700.0 0.66 368040.0 -60800.0 -0.52 0.1028 0.1226 3187880 BCB03_000464 CC(C)(C)OC(=O)N(CC#C)[C@H](CO)c1ccccc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H08 compound treatment 464590.0 12800.0 0.11 436000.0 7160.0 0.06 0.1199 0.962 2133035 BCB03_000465 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CC3CCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H09 compound treatment 53470.0 -398000.0 -3.39 11360.0 -417000.0 -3.54 -4.9003 -0.9998 3071519 BCB03_000466 CC(=CCN([C@H](CO)c1ccccc1)C(=O)C#Cc2ccccc2)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H10 compound treatment 460530.0 8730.0 0.07 488050.0 59200.0 0.5 0.4077 0.8029 2133267 BCB03_000467 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(Cc3ccc(F)cc3)C(=O)C4CCCO4)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H11 compound treatment 421810.0 -30000.0 -0.26 268170.0 -161000.0 -1.36 -1.1441 -0.8251 3071520 BCB03_000468 OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H12 compound treatment 435840.0 -16000.0 -0.14 452930.0 24100.0 0.2 0.0485 0.1976 2133153 BCB03_000469 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCN3CCOCC3)C(=O)C4CCOC4)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H13 compound treatment 478880.0 27100.0 0.23 456820.0 28000.0 0.24 0.3307 0.9999 3071521 BCB03_000470 CC(C)(C)[Si](C)(C)OC[C@@H](N(C/C=C/c1ccccc1)CC#C)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H14 compound treatment 460900.0 9100.0 0.08 469560.0 40700.0 0.35 0.299 0.8447 2132929 BCB03_000471 CC/C=C/C(=O)N(C[C@@H]1CCCO1)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H15 compound treatment 445880.0 -5920.0 -0.05 381130.0 -47700.0 -0.4 -0.3218 -0.789 3071522 BCB03_000472 O=C1OC[C@H](N2CC(=CC21)/C=C/c3ccccc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H16 compound treatment 444220.0 -7580.0 -0.06 388570.0 -40300.0 -0.34 -0.2871 -0.826 2133065 BCB03_000473 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(C3CCCCCC3)C(=O)c4cc5ccccc5oc4=O)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H17 compound treatment 438970.0 -12800.0 -0.11 435790.0 6950.0 0.06 -0.0355 -0.2861 3071523 BCB03_000474 OCC(/C=C/c1ccccc1)N(CC#C)Cc2ccccc2Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H18 compound treatment 512280.0 60500.0 0.51 482200.0 53400.0 0.45 0.6839 0.998 2133224 BCB03_000475 CCCCC(=O)N(Cc1ccccc1F)[C@@H]2CC(=C[C@H](Oc3c(I)cc(CO)cc3OC)[C@H]2O)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H19 mock treatment 392000.0 -59800.0 -0.51 437170.0 8330.0 0.07 -0.3098 -0.6031 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H20 mock treatment 363550.0 -88200.0 -0.75 460800.0 32000.0 0.27 -0.3392 -0.4249 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H21 compound treatment 360960.0 -90800.0 -0.77 315230.0 -114000.0 -0.96 -1.2279 -0.994 3071524 BCB03_000476 OCC1C=C(CN1Cc2ccccc2Br)/C=C/c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H22 compound treatment 384110.0 -67700.0 -0.58 284130.0 -145000.0 -1.23 -1.2752 -0.9405 2133510 BCB03_000477 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@H]([C@@H]2O)N(CCc3cccc(F)c3)C(=O)CCC4CCCC4)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H23 compound treatment 428710.0 -23100.0 -0.2 391970.0 -36900.0 -0.31 -0.3601 -0.9749 3414064 BCB03_000478 O=S1(=O)N2CCC[C@@H]2[C@@H](Oc3ccccc31)C#C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 H24 compound treatment 357840.0 -94000.0 -0.8 223470.0 -205000.0 -1.74 -1.7971 -0.9376 2128988 BCB03_000479 COc1cc(CO)cc(I)c1O[C@H]2C=C(C[C@@H]3O[C@@H]32)C(=O)NCCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I01 compound treatment 497820.0 46000.0 0.39 437530.0 8690.0 0.07 0.329 0.8257 3070742 BCB03_000480 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I02 compound treatment 522880.0 71100.0 0.6 443120.0 14300.0 0.12 0.5132 0.8322 3189420 BCB03_000481 COc1ccc(cc1)[C@H]2OC[C@@H]3C[C@](Cc4ccccc4)(C(=O)OCC=C)C(=O)N23 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I03 compound treatment 467090.0 15300.0 0.13 321200.0 -108000.0 -0.91 -0.5537 -0.6003 3070750 BCB03_000482 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(n2)c4ccc(Oc5ccccc5)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I04 compound treatment 524180.0 72400.0 0.62 463720.0 34900.0 0.3 0.6446 0.9436 1035256 BCB03_000483 C#CCNCc1ccccc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I05 mock treatment 450620.0 -1180.0 -0.01 502160.0 73300.0 0.62 0.4327 0.6956 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I06 mock treatment 491000.0 39200.0 0.33 395360.0 -33500.0 -0.28 0.035 0.0799 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I07 compound treatment 477860.0 26100.0 0.22 408550.0 -20300.0 -0.17 0.0351 0.1249 3188915 BCB03_000484 CC(C)[Si]1(OCc2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I08 compound treatment 473130.0 21300.0 0.18 444980.0 16100.0 0.14 0.2251 0.9903 3071258 BCB03_000485 CC(C)[C@H](N=[N+]=[N-])C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC#C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I09 compound treatment 497280.0 45500.0 0.39 484740.0 55900.0 0.47 0.6089 0.9949 3070808 BCB03_000486 CC(C)[Si]1(O[C@H](c2cc(nc(c21)c3ccc(Oc4ccccc4)cc3)C5CC5)c6ccccc6)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I10 compound treatment 513310.0 61500.0 0.52 455430.0 26600.0 0.23 0.5295 0.9292 3189550 BCB03_000487 COc1cccc(C[C@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I11 compound treatment 478820.0 27000.0 0.23 397170.0 -31700.0 -0.27 -0.0274 -0.0776 3070078 BCB03_000488 CC[C@@H]1O[Si](C(C)C)(C(C)C)c2c1cc(nc2c3ccc(Oc4ccccc4)cc3)c5cc(C)c(OC)c(C)c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I12 compound treatment 514770.0 63000.0 0.54 427250.0 -1590.0 -0.01 0.3693 0.6891 3189551 BCB03_000489 COc1cccc(C[C@@]2(C[C@@H](CO)NC2=O)C(=O)OCc3ccccc3)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I13 compound treatment 506090.0 54300.0 0.46 439470.0 10600.0 0.09 0.3903 0.8295 3070690 BCB03_000490 CCCCCCc1nc(cc2CO[Si](C(C)C)(C(C)C)c21)C(=C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I14 compound treatment 454020.0 2220.0 0.02 457950.0 29100.0 0.25 0.188 0.759 3071267 BCB03_000491 CN(C)S(=O)(=O)NCC#C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I15 compound treatment 458910.0 7110.0 0.06 224800.0 -204000.0 -1.73 -1.1811 -0.682 3071259 BCB03_000492 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#Cc4ccccc4)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I16 compound treatment 315310.0 -136000.0 -1.16 361370.0 -67500.0 -0.57 -1.2258 -0.9469 3189556 BCB03_000493 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N(Cc3ccccc3)Cc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I17 compound treatment 433830.0 -18000.0 -0.15 383590.0 -45300.0 -0.38 -0.3795 -0.9185 3071266 BCB03_000494 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCc4ccccc4)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I18 compound treatment 427200.0 -24600.0 -0.21 459070.0 30200.0 0.26 0.0333 0.1007 3188911 BCB03_000495 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I19 compound treatment 486880.0 35100.0 0.3 364230.0 -64600.0 -0.55 -0.1765 -0.2828 3189415 BCB03_000496 CCCCCCC#C[Si](O[C@@H](C#C)c1ccccc1)(C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I20 compound treatment 353210.0 -98600.0 -0.84 398670.0 -30200.0 -0.26 -0.774 -0.8827 3188912 BCB03_000497 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](C)Cn3cc(CN(C)C2=O)nn3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I21 mock treatment 466920.0 15100.0 0.13 434620.0 5780.0 0.05 0.1256 0.9126 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I22 mock treatment 370420.0 -81400.0 -0.69 374210.0 -54600.0 -0.46 -0.8172 -0.9809 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I23 compound treatment 448000.0 -3800.0 -0.03 306730.0 -122000.0 -1.04 -0.7553 -0.7288 3189416 BCB03_000498 CCCCCCC#C[Si](OCC#CC)(C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 I24 compound treatment 455730.0 3930.0 0.03 397120.0 -31700.0 -0.27 -0.1666 -0.6145 3188913 BCB03_000499 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)Cn4cc(CN(C)C2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J01 compound treatment 462930.0 11100.0 0.09 348320.0 -80500.0 -0.68 -0.416 -0.6033 3071594 BCB03_000500 O=S1(=O)N2CCC[C@H]2[C@H](Oc3ccccc31)C#C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J02 compound treatment 388230.0 -63600.0 -0.54 225160.0 -204000.0 -1.73 -1.6041 -0.886 3187871 BCB03_000501 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)N(Cc3ccco3)C(=O)Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J03 compound treatment 414880.0 -36900.0 -0.31 497710.0 68900.0 0.58 0.191 0.288 3071530 BCB03_000502 CCOC(=O)[C@H]1C[C@H]2O[C@]32C[C@H]1C(=O)N4CCCC4[C@@H]3O[Si](C)(C)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J04 compound treatment 369530.0 -82300.0 -0.7 369880.0 -59000.0 -0.5 -0.8486 -0.9864 2129008 BCB03_000503 OCCNC(=O)C1=C[C@H](Oc2ccccc2I)[C@@H](O)[C@@H](C1)NCc3ccc(F)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J05 mock treatment 399940.0 -51900.0 -0.44 364210.0 -64600.0 -0.55 -0.6996 -0.9942 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J06 mock treatment 540400.0 88600.0 0.75 420410.0 -8430.0 -0.07 0.4824 0.6372 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J07 compound treatment 459040.0 7240.0 0.06 398590.0 -30300.0 -0.26 -0.1379 -0.5225 3071528 BCB03_000504 CCOC(=O)[C@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@@H]2O[Si](C)(C)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J08 compound treatment 359060.0 -92700.0 -0.79 359050.0 -69800.0 -0.59 -0.9765 -0.99 3187877 BCB03_000505 CC(C)C[C@@H]1NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC(=O)[C@@H](C)NC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J09 compound treatment 509760.0 58000.0 0.49 445680.0 16800.0 0.14 0.4497 0.8759 3071529 BCB03_000506 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J10 compound treatment 386680.0 -65100.0 -0.55 315790.0 -113000.0 -0.96 -1.0698 -0.966 3188005 BCB03_000507 CC(C)C[C@@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J11 compound treatment 501790.0 50000.0 0.43 458280.0 29400.0 0.25 0.4773 0.9678 3071527 BCB03_000508 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J12 compound treatment 376700.0 -75100.0 -0.64 359760.0 -69100.0 -0.59 -0.8661 -0.9991 3188007 BCB03_000509 CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/CC\C=C\CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J13 compound treatment 439090.0 -12700.0 -0.11 349610.0 -79200.0 -0.67 -0.5517 -0.8104 3071654 BCB03_000510 [O-][N+](=O)c1ccccc1S(=O)(=O)N2CCC[C@@H]2[C@H]3OCC=C3C(=C)C=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J14 compound treatment 369880.0 -81900.0 -0.7 373770.0 -55100.0 -0.47 -0.8231 -0.9811 3188008 BCB03_000511 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/CC\C=C\CNC(=O)[C@@H]5CCCN5C(=O)[C@H](Cc6ccccc6)NC4=O)[C@@H]7O[C@@]71C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J15 compound treatment 140910.0 -311000.0 -2.64 106240.0 -323000.0 -2.74 -3.8052 -0.9999 3071597 BCB03_000512 Cc1ccc(cc1)S(=O)(=O)NC/C=C\C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J16 compound treatment 370090.0 -81700.0 -0.7 319920.0 -109000.0 -0.92 -1.1449 -0.9902 3188142 BCB03_000513 C[C@@H](OCc1ccccc1)C2NC(=O)[C@@]3(C4[C@H](Cc5ccccc5)NC3=O)C(/C=C/C\C=C/CNC(=O)[C@@H](C)NC2=O)[C@@H]6O[C@]6(C)[C@H]4C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J17 compound treatment 380170.0 -71600.0 -0.61 225550.0 -203000.0 -1.72 -1.6503 -0.9023 3071598 BCB03_000514 Cc1ccc(cc1)S(=O)(=O)NC/C=C/C(=C)[C@H](O)[C@H]2CCCN2S(=O)(=O)c3ccccc3[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J18 compound treatment 357970.0 -93800.0 -0.8 349480.0 -79400.0 -0.67 -1.0405 -0.9964 3188271 BCB03_000515 CC(C)C[C@H]1NC(=O)CNC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J19 compound treatment 242850.0 -209000.0 -1.78 126420.0 -302000.0 -2.57 -3.0709 -0.9839 3188138 BCB03_000516 Cc1ccc(cc1)S(=O)(=O)N(CCC=C)CC#C[C@H]2Oc3ccccc3S(=O)(=O)N4CCC[C@@H]24 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J20 compound treatment 336800.0 -115000.0 -0.98 297730.0 -131000.0 -1.11 -1.4782 -0.998 3188272 BCB03_000517 CC(C)C[C@H]1NC(=O)C(NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C)[C@@H](C)OCc6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J21 mock treatment 445130.0 -6670.0 -0.06 377440.0 -51400.0 -0.44 -0.3484 -0.7924 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J22 mock treatment 398900.0 -52900.0 -0.45 304180.0 -125000.0 -1.06 -1.066 -0.9275 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J23 compound treatment 356200.0 -95600.0 -0.81 252130.0 -177000.0 -1.5 -1.635 -0.9587 3071656 BCB03_000518 CN1C(=C)C2CC3C4C(C5CO[C@H]([C@H]6CCCN6S(=O)(=O)c7ccccc7[N+](=O)[O-])C5=C3CC2C1=O)C(=O)N(C)C4=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 J24 compound treatment 301930.0 -150000.0 -1.27 294090.0 -135000.0 -1.14 -1.7098 -0.9985 3188275 BCB03_000519 CC(C)C[C@H]1NC(=O)[C@H](C)NC(=O)[C@@]2(C3[C@H](Cc4ccccc4)NC2=O)C(/C=C/C\C=C/CNC1=O)[C@@H]5O[C@]5(C)[C@H]3C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K01 compound treatment 267440.0 -184000.0 -1.57 203470.0 -225000.0 -1.91 -2.4608 -0.9952 3071254 BCB03_000520 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccccc2)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K02 compound treatment 474810.0 23000.0 0.2 317600.0 -111000.0 -0.94 -0.5288 -0.5487 3220747 BCB03_000521 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCCC2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K03 compound treatment 515690.0 63900.0 0.54 427470.0 -1370.0 -0.01 0.3761 0.6918 3189418 BCB03_000522 CC#CCO[Si](C#Cc1ccccc1)(C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K04 compound treatment 490140.0 38300.0 0.33 431570.0 2730.0 0.02 0.247 0.7554 3220749 BCB03_000523 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCC(C)C)oc(C(=O)Cc2ccccc2)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K05 compound treatment 401240.0 -50600.0 -0.43 399840.0 -29000.0 -0.25 -0.4781 -0.9649 3071256 BCB03_000524 CC(C)[Si](O[C@@H](C#C)c1ccccc1)(C#Cc2ccc(Oc3ccccc3)cc2)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K06 compound treatment 520480.0 68700.0 0.58 404250.0 -24600.0 -0.21 0.2657 0.4282 3220751 BCB03_000525 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2ccc(OC)cc2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K07 mock treatment 445350.0 -6450.0 -0.05 509160.0 80300.0 0.68 0.443 0.6481 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K08 mock treatment 479620.0 27800.0 0.24 500040.0 71200.0 0.6 0.5944 0.9164 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K09 compound treatment 465090.0 13300.0 0.11 331200.0 -97600.0 -0.83 -0.5057 -0.605 3071257 BCB03_000526 CC[C@@H](O[Si](C#Cc1ccc(Oc2ccccc2)cc1)(C(C)C)C(C)C)C#C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K10 compound treatment 504850.0 53100.0 0.45 466280.0 37400.0 0.32 0.5437 0.9852 3220772 BCB03_000527 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCc2c[nH]c3ccccc23)oc(C(=O)Cc4ccccc4)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K11 compound treatment 504660.0 52900.0 0.45 447840.0 19000.0 0.16 0.4319 0.9042 3189421 BCB03_000528 CC(C)[Si](Oc1ccccc1Br)(C#CCCCC#N)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K12 compound treatment 522050.0 70300.0 0.6 469520.0 40700.0 0.35 0.6666 0.9659 3220775 BCB03_000529 COC(=O)c1c(CC[C@@H](CO)NC(=O)Nc2nc[nH]n2)oc(C(=O)Cc3ccccc3)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K13 compound treatment 338100.0 -114000.0 -0.97 283360.0 -145000.0 -1.23 -1.5566 -0.9927 3189422 BCB03_000530 CC[C@@H](O[Si](C#CCCCC#N)(C(C)C)C(C)C)C#C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K14 compound treatment 494400.0 42600.0 0.36 497600.0 68800.0 0.58 0.6687 0.9738 3220649 BCB03_000531 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K15 mock treatment 574920.0 123000.0 1.05 504720.0 75900.0 0.64 1.1958 0.9727 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K16 mock treatment 568250.0 116000.0 0.99 414520.0 -14300.0 -0.12 0.6146 0.6158 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K17 compound treatment 550580.0 98800.0 0.84 435360.0 6520.0 0.06 0.6333 0.752 3189552 BCB03_000532 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K18 compound treatment 547650.0 95900.0 0.82 531740.0 103000.0 0.87 1.1938 0.9994 3220651 BCB03_000533 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4cncn4C)oc(C(=O)C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K19 compound treatment 447620.0 -4180.0 -0.04 403680.0 -25200.0 -0.21 -0.1761 -0.8137 3189553 BCB03_000534 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](CO)Cc2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K20 compound treatment 466030.0 14200.0 0.12 482150.0 53300.0 0.45 0.4054 0.8659 3220653 BCB03_000535 CCCCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K21 compound treatment 526440.0 74600.0 0.63 406170.0 -22700.0 -0.19 0.313 0.4718 3189554 BCB03_000536 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(Cc2cccc(Cl)c2)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K22 compound treatment 416740.0 -35100.0 -0.3 376160.0 -52700.0 -0.45 -0.5269 -0.9807 3220655 BCB03_000537 CCOC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K23 mock treatment 493790.0 42000.0 0.36 428530.0 -311.0 0.0 0.2507 0.7019 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 K24 mock treatment 441700.0 -10100.0 -0.09 404710.0 -24100.0 -0.2 -0.2055 -0.9257 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L01 compound treatment 448900.0 -2900.0 -0.02 480660.0 51800.0 0.44 0.2934 0.6664 3071655 BCB03_000538 CN1C(=O)C2CC=C(CC2C1=O)C3=CCO[C@@H]3[C@H]4CCCN4S(=O)(=O)c5ccccc5[N+](=O)[O-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L02 compound treatment 321510.0 -130000.0 -1.11 329760.0 -99100.0 -0.84 -1.3781 -0.9907 3188392 BCB03_000539 C[C@H]1C2[C@H](Cc3ccccc3)NC(=O)[C@@]24C(/C=C/C\C=C/CNC(=O)[C@@H]5CCCN5C(=O)CNC4=O)[C@@H]6O[C@@]61C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L03 compound treatment 434080.0 -17700.0 -0.15 428910.0 68.9 0.0 -0.1062 -0.7044 3188141 BCB03_000540 C=CC(=C)[C@H]1Oc2ccccc2S(=O)(=O)N3CCC[C@@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L04 compound treatment 465810.0 14000.0 0.12 448370.0 19500.0 0.17 0.2014 0.987 3188274 BCB03_000541 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L05 compound treatment 511840.0 60000.0 0.51 496770.0 67900.0 0.58 0.7686 0.9982 3071592 BCB03_000542 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L06 compound treatment 456100.0 4300.0 0.04 417980.0 -10900.0 -0.09 -0.0393 -0.3962 3070931 BCB03_000543 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L07 mock treatment 528860.0 77100.0 0.66 480590.0 51700.0 0.44 0.774 0.981 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L08 mock treatment 473360.0 21600.0 0.18 440800.0 12000.0 0.1 0.2014 0.961 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L09 compound treatment 481380.0 29600.0 0.25 514200.0 85400.0 0.72 0.6899 0.9001 3071592 BCB03_000544 CN1C(=O)C2CC=C(CC2C1=O)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L10 compound treatment 468330.0 16500.0 0.14 411420.0 -17400.0 -0.15 -0.0051 -0.0248 3070933 BCB03_000545 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L11 compound treatment 441290.0 -10500.0 -0.09 405820.0 -23000.0 -0.2 -0.2013 -0.9373 3071581 BCB03_000546 O=C1C2CC=C(CC2C(=O)c3ccccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L12 compound treatment 402840.0 -49000.0 -0.42 358480.0 -70400.0 -0.6 -0.7166 -0.9845 3188523 BCB03_000547 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L13 compound treatment 461830.0 10000.0 0.09 406920.0 -21900.0 -0.19 -0.0711 -0.3477 3071582 BCB03_000548 O=C1c2ccccc2C(=O)c3cc(ccc13)[C@H]4Oc5ccccc5S(=O)(=O)N6CCC[C@@H]46 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L14 compound treatment 544250.0 92500.0 0.79 451040.0 22200.0 0.19 0.6893 0.8523 3188524 BCB03_000549 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L15 mock treatment 542480.0 90700.0 0.77 453550.0 24700.0 0.21 0.6937 0.8678 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L16 mock treatment 533070.0 81300.0 0.69 475860.0 47000.0 0.4 0.7709 0.9658 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L17 compound treatment 440390.0 -11400.0 -0.1 396860.0 -32000.0 -0.27 -0.2605 -0.904 3071529 BCB03_000550 CCOC(=O)[C@@H]1CC2O[C@@]32C[C@@H]1C(=O)N4CCC[C@@H]4[C@H]3O[Si](C)(C)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L18 compound treatment 355580.0 -96200.0 -0.82 467080.0 38200.0 0.32 -0.3494 -0.3969 3188525 BCB03_000551 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2n4n(C1)c(=O)n(c5ccccc5)c4=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L19 compound treatment 461920.0 10100.0 0.09 411890.0 -17000.0 -0.14 -0.0408 -0.2434 3071527 BCB03_000552 CCOC(=O)[C@@H]1CC=C2CC1C(=O)N3CCC[C@@H]3[C@H]2O[Si](C)(C)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L20 compound treatment 432760.0 -19000.0 -0.16 384800.0 -44000.0 -0.37 -0.3787 -0.93 3188526 BCB03_000553 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@@H](CCc6ccccc6)O1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L21 compound treatment 433770.0 -18000.0 -0.15 248660.0 -180000.0 -1.53 -1.1892 -0.7742 3071531 BCB03_000554 CCOC(=O)[C@@H]1[C@@H]2CN(CCC2=C[C@@H]3[C@@H](O[Si](C(C)C)(C(C)C)C(C)C)[C@@H]4CCCN4C(=O)[C@@H]13)S(=O)(=O)c5ccc(C)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L22 compound treatment 458310.0 6510.0 0.06 330490.0 -98400.0 -0.83 -0.5508 -0.6587 3188538 BCB03_000555 CCCC[C@H]1OB(O)C[C@H]2C1=C(C)Cn3n2c(=O)n(c4ccccc4)c3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L23 mock treatment 479380.0 27600.0 0.23 450460.0 21600.0 0.18 0.2956 0.9926 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 L24 mock treatment 402480.0 -49300.0 -0.42 429300.0 459.0 0.0 -0.2939 -0.7005 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M01 compound treatment 471080.0 19300.0 0.16 465130.0 36300.0 0.31 0.3337 0.9566 3071269 BCB03_000556 CC[C@@H](O[Si](C#C[Si](C(C)C)(C(C)C)C(C)C)(C(C)C)C(C)C)c1cn(nn1)[C@H](C)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M02 compound treatment 484960.0 33200.0 0.28 508100.0 79300.0 0.67 0.6749 0.9256 3220657 BCB03_000557 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)c3ccccn3)oc(C(=O)C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M03 compound treatment 465170.0 13400.0 0.11 396960.0 -31900.0 -0.27 -0.1108 -0.3776 3189557 BCB03_000558 CCCC#C[Si](O[C@H](CC)c1cn(Cc2ccccc2)nn1)(C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M04 compound treatment 475710.0 23900.0 0.2 496960.0 68100.0 0.58 0.5524 0.9018 3220659 BCB03_000559 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCCC3)oc(C(=O)C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M05 compound treatment 477160.0 25400.0 0.22 437050.0 8210.0 0.07 0.2018 0.8901 3071329 BCB03_000560 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M06 compound treatment 497530.0 45700.0 0.39 466720.0 37900.0 0.32 0.5023 0.9955 3220661 BCB03_000561 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](C)Cn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M07 compound treatment 473890.0 22100.0 0.19 412960.0 -15900.0 -0.13 0.0376 0.1628 3071331 BCB03_000562 CCCC#C[Si](O[C@H](CC)c1cn(nn1)[C@H](C)c2ccccc2)(C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M08 compound treatment 482410.0 30600.0 0.26 424860.0 -3980.0 -0.03 0.1603 0.6103 3220665 BCB03_000563 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(Cc3ccccc3)nn2)C(C)C)oc(C(=O)C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M09 mock treatment 503120.0 51300.0 0.44 489410.0 60600.0 0.51 0.672 0.9967 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M10 mock treatment 533660.0 81900.0 0.7 495130.0 66300.0 0.56 0.8901 0.9944 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M11 compound treatment 472380.0 20600.0 0.18 458270.0 29400.0 0.25 0.3003 0.9849 3071332 BCB03_000564 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M12 compound treatment 466510.0 14700.0 0.13 439780.0 10900.0 0.09 0.1541 0.9892 3220667 BCB03_000565 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)C3(O)CCCCC3)C(C)C)oc(C(=O)C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M13 mock treatment 499440.0 47600.0 0.41 470640.0 41800.0 0.35 0.5373 0.9978 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M14 mock treatment 498160.0 46400.0 0.39 481140.0 52300.0 0.44 0.5926 0.9983 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M15 compound treatment 492580.0 40800.0 0.35 439010.0 10200.0 0.09 0.3063 0.8568 3189692 BCB03_000566 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M16 compound treatment 489620.0 37800.0 0.32 449030.0 20200.0 0.17 0.3486 0.9564 3220669 BCB03_000567 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cn2cc(nn2)c3cncn3C)C(C)C)oc(C(=O)C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M17 compound treatment 452960.0 1160.0 0.01 476270.0 47400.0 0.4 0.2915 0.7243 3189693 BCB03_000568 CCCCCCC#C[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M18 compound treatment 536000.0 84200.0 0.72 508160.0 79300.0 0.67 0.9823 0.9995 3414054 BCB03_000569 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M19 compound treatment 453360.0 1560.0 0.01 408820.0 -20000.0 -0.17 -0.1107 -0.6498 3189694 BCB03_000570 CCCCCCC#C[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M20 compound treatment 405310.0 -46500.0 -0.4 481220.0 52400.0 0.44 0.0345 0.058 3414055 BCB03_000571 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(Cc4ccccc4)nn3)oc(C(=O)C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M21 compound treatment 462270.0 10500.0 0.09 410240.0 -18600.0 -0.16 -0.0486 -0.2681 3071395 BCB03_000572 CC(C)[Si](O[C@@H](c1cn(Cc2ccccc2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M22 compound treatment 433450.0 -18300.0 -0.16 429000.0 159.0 0.0 -0.1094 -0.701 3414056 BCB03_000573 COC(=O)c1c(CC[C@@H](CO)NC(=O)N2CCC[C@H]2Cn3cc(nn3)C4(O)CCCCC4)oc(C(=O)C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M23 compound treatment 381400.0 -70400.0 -0.6 424540.0 -4300.0 -0.04 -0.4493 -0.7488 3189697 BCB03_000574 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](CO)Cc2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 M24 compound treatment 462720.0 10900.0 0.09 426610.0 -2230.0 -0.02 0.0523 0.5517 3414057 BCB03_000575 CCCCc1cn(C[C@@H]2CCCN2C(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N01 compound treatment 410620.0 -41200.0 -0.35 350530.0 -78300.0 -0.66 -0.7174 -0.9553 3071585 BCB03_000576 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N02 compound treatment 463940.0 12100.0 0.1 459700.0 30900.0 0.26 0.2581 0.9173 3215882 BCB03_000577 CCCC[C@H]1OB(O)C[C@H]2C1=C(COC)Cn3n2c(=O)n(c4ccccc4)c3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N03 compound treatment 431720.0 -20100.0 -0.17 391470.0 -37400.0 -0.32 -0.3449 -0.9579 3188130 BCB03_000578 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N04 compound treatment 477490.0 25700.0 0.22 327160.0 -102000.0 -0.86 -0.4554 -0.5118 3215880 BCB03_000579 CCCC[C@H]1OB(O)C[C@H]2C1=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N05 compound treatment 454140.0 2340.0 0.02 432390.0 3550.0 0.03 0.0354 0.9799 3071587 BCB03_000580 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N06 compound treatment 327420.0 -124000.0 -1.06 286560.0 -142000.0 -1.21 -1.6016 -0.9978 3188542 BCB03_000581 CC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N07 compound treatment 348040.0 -104000.0 -0.88 311450.0 -117000.0 -1.0 -1.3283 -0.9982 3071588 BCB03_000582 BrC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N08 compound treatment 413690.0 -38100.0 -0.32 410240.0 -18600.0 -0.16 -0.3408 -0.9452 3071661 BCB03_000583 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(Cc5ccccc5)C4=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N09 mock treatment 475780.0 24000.0 0.2 447900.0 19100.0 0.16 0.2586 0.9934 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N10 mock treatment 511170.0 59400.0 0.51 494320.0 65500.0 0.56 0.7499 0.9989 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N11 compound treatment 328800.0 -123000.0 -1.05 305000.0 -124000.0 -1.05 -1.4827 -1.0 3071589 BCB03_000584 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N12 compound treatment 258410.0 -193000.0 -1.65 242490.0 -186000.0 -1.58 -2.2811 -0.9998 3188543 BCB03_000585 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)C=CC4=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N13 mock treatment 507860.0 56100.0 0.48 480510.0 51700.0 0.44 0.6472 0.9991 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N14 mock treatment 518680.0 66900.0 0.57 498680.0 69800.0 0.59 0.8212 0.9998 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N15 compound treatment 395550.0 -56200.0 -0.48 298190.0 -131000.0 -1.11 -1.122 -0.9295 3071590 BCB03_000586 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N16 compound treatment 352020.0 -99800.0 -0.85 331260.0 -97600.0 -0.83 -1.1855 -0.9999 3070948 BCB03_000587 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)C=CC3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N17 compound treatment 347360.0 -104000.0 -0.89 278340.0 -151000.0 -1.28 -1.531 -0.9843 3071591 BCB03_000588 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N18 compound treatment 248480.0 -203000.0 -1.73 181550.0 -247000.0 -2.1 -2.7064 -0.9954 3070949 BCB03_000589 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)C=CC3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N19 compound treatment 264320.0 -187000.0 -1.59 309780.0 -119000.0 -1.01 -1.8419 -0.9757 3188261 BCB03_000590 CO[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3cccc(C)c3)C(=O)[C@@]42CO4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N20 compound treatment 210560.0 -241000.0 -2.05 173940.0 -255000.0 -2.16 -2.9801 -0.9997 3070950 BCB03_000591 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)C=CC3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N21 compound treatment 294180.0 -158000.0 -1.34 336670.0 -92200.0 -0.78 -1.501 -0.967 3071600 BCB03_000592 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(OC)C(=O)[C@@]43CO4)Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N22 compound treatment 301930.0 -150000.0 -1.27 228820.0 -200000.0 -1.7 -2.1013 -0.9901 3070951 BCB03_000593 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)C=CC3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N23 compound treatment 343560.0 -108000.0 -0.92 388480.0 -40400.0 -0.34 -0.8932 -0.9092 3071601 BCB03_000594 OCCOCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 N24 compound treatment 416800.0 -35000.0 -0.3 298190.0 -131000.0 -1.11 -0.9942 -0.8664 3071664 BCB03_000595 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@@H](CCc4ccccc4)O1)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O01 compound treatment 321130.0 -131000.0 -1.11 350160.0 -78700.0 -0.67 -1.258 -0.9702 3187592 BCB03_000596 CC(C)[Si](O[C@@H](c1cn(Cc2cccc(Cl)c2)nn1)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O02 compound treatment 419040.0 -32800.0 -0.28 461830.0 33000.0 0.28 8.0E-4 0.0021 3220705 BCB03_000597 CCc1oc(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCCC3)c(C(=O)OC)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O03 compound treatment 443750.0 -8050.0 -0.07 393440.0 -35400.0 -0.3 -0.2608 -0.8466 3071397 BCB03_000598 CC(C)[Si](O[C@@H](c1cn(nn1)[C@H](C)c2ccccc2)c3ccccc3)(C#CCCCC#N)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O04 compound treatment 409660.0 -42100.0 -0.36 412570.0 -16300.0 -0.14 -0.3511 -0.914 3220708 BCB03_000599 COC(=O)c1c(CC[C@@H](CO)NC(=O)NCCn2cc(nn2)C3(O)CCCC3)oc(C(=O)C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O05 compound treatment 428060.0 -23700.0 -0.2 431150.0 2310.0 0.02 -0.129 -0.6355 3071398 BCB03_000600 CC(C)[Si](O[C@H](C)c1cn(Cc2ccccc2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O06 compound treatment 491100.0 39300.0 0.33 377350.0 -51500.0 -0.44 -0.0724 -0.1317 3220711 BCB03_000601 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O07 compound treatment 424070.0 -27700.0 -0.24 429140.0 299.0 0.0 -0.165 -0.6995 3071399 BCB03_000602 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](CO)Cc2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O08 compound treatment 463490.0 11700.0 0.1 454630.0 25800.0 0.22 0.225 0.9364 3220713 BCB03_000603 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4N)oc(C(=O)C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O09 compound treatment 454340.0 2540.0 0.02 400870.0 -28000.0 -0.24 -0.1525 -0.64 3187596 BCB03_000604 CC(C)[Si](O[C@H](C)c1cn(Cc2cccc(Cl)c2)nn1)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O10 compound treatment 443840.0 -7960.0 -0.07 446040.0 17200.0 0.15 0.0553 0.3437 3220715 BCB03_000605 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)C)c(C(=O)OC)c3C(=O)OC)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O11 mock treatment 467600.0 15800.0 0.13 421760.0 -7080.0 -0.06 0.0526 0.3571 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O12 mock treatment 513330.0 61500.0 0.52 409760.0 -19100.0 -0.16 0.2557 0.4667 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O13 compound treatment 481030.0 29200.0 0.25 423080.0 -5760.0 -0.05 0.1413 0.5575 3071400 BCB03_000606 CC(C)[Si](O[C@H](C)c1cn(nn1)[C@H](C)c2ccccc2)(C#C[Si](C(C)C)(C(C)C)C(C)C)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O14 compound treatment 449210.0 -2590.0 -0.02 345340.0 -83500.0 -0.71 -0.5164 -0.7287 3220717 BCB03_000607 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccc4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O15 compound treatment 454600.0 2800.0 0.02 404990.0 -23900.0 -0.2 -0.1262 -0.6195 3070694 BCB03_000608 COc1ccc(cn1)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O16 compound treatment 462400.0 10600.0 0.09 382880.0 -46000.0 -0.39 -0.2119 -0.5296 3220739 BCB03_000609 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)c4ccccn4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O17 compound treatment 408260.0 -43500.0 -0.37 430450.0 1610.0 0.01 -0.2523 -0.6806 3070746 BCB03_000610 COc1c(C)cc(cc1C)c2cc3CO[Si](C(C)C)(C(C)C)c3c(Cc4ccccc4)n2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O18 compound treatment 460850.0 9050.0 0.08 426910.0 -1930.0 -0.02 0.0429 0.5445 3220741 BCB03_000611 COC(=O)c1c(CC[C@@H](CO)NC(=O)N[C@@H](Cc2ccccc2)Cn3cc(nn3)C4(O)CCCC4)oc(C(=O)N5CCOCC5)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O19 compound treatment 347360.0 -104000.0 -0.89 277660.0 -151000.0 -1.28 -1.5351 -0.9839 3188534 BCB03_000612 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@@H]3[C@H]2[C@H](O)Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O20 compound treatment 427680.0 -24100.0 -0.21 367370.0 -61500.0 -0.52 -0.5138 -0.9169 3220743 BCB03_000613 COCc1cn(C[C@H](Cc2ccccc2)NC(=O)N[C@H](CO)CCc3oc(C(=O)N4CCOCC4)c(C(=O)OC)c3C(=O)OC)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O21 compound treatment 282050.0 -170000.0 -1.44 253610.0 -175000.0 -1.49 -2.0722 -0.9999 3188535 BCB03_000614 COC(=O)[C@H](Cc1ccccc1)N2CC(=C)[C@H](/C=C/C=C)[C@H]2[C@H](O)Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O22 compound treatment 373690.0 -78100.0 -0.66 380800.0 -48000.0 -0.41 -0.758 -0.9725 3188660 BCB03_000615 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O23 compound treatment 394850.0 -56900.0 -0.48 346900.0 -81900.0 -0.7 -0.8341 -0.9844 3188536 BCB03_000616 O=C1O[C@H](Cc2ccccc2)[C@H](/C=C/C3CC3)N(CC#C)[C@H]1Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 O24 compound treatment 255090.0 -197000.0 -1.67 304240.0 -125000.0 -1.06 -1.9307 -0.9754 3188661 BCB03_000617 COC(=O)[C@H](Cc1ccccc1)N(CC#C)[C@H](/C=C/C2CC2)[C@@H](O)Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P01 compound treatment 278000.0 -174000.0 -1.48 230560.0 -198000.0 -1.68 -2.2348 -0.9979 3071602 BCB03_000618 OCCCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P02 compound treatment 318610.0 -133000.0 -1.13 315710.0 -113000.0 -0.96 -1.4798 -0.9966 3071666 BCB03_000619 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)C)C(=O)N(Cc4ccccc4)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P03 compound treatment 273250.0 -179000.0 -1.52 237080.0 -192000.0 -1.63 -2.2243 -0.9994 3071603 BCB03_000620 OCCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P04 compound treatment 296540.0 -155000.0 -1.32 317470.0 -111000.0 -0.94 -1.602 -0.9865 3071711 BCB03_000621 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COC)C(=O)N(Cc4ccccc4)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P05 compound treatment 215680.0 -236000.0 -2.01 264280.0 -165000.0 -1.4 -2.4075 -0.9842 3071604 BCB03_000622 CCCCO[C@H]1C[C@H]2C(=C[C@@H]1C(=O)[C@@]32CO3)I 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P06 compound treatment 258260.0 -194000.0 -1.65 294000.0 -135000.0 -1.14 -1.973 -0.9842 3071776 BCB03_000623 CCCC[C@H]1OB(O)C[C@@H]2[C@H]3[C@@H](CC(=C12)COc4ccccc4)C(=O)N(Cc5ccccc5)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P07 compound treatment 158500.0 -293000.0 -2.5 149920.0 -279000.0 -2.37 -3.4374 -0.9996 3071651 BCB03_000624 IC1=C[C@H]2[C@H](C[C@@H]1[C@@]3(CO3)C2=O)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P08 compound treatment 306250.0 -146000.0 -1.24 224090.0 -205000.0 -1.74 -2.1037 -0.9862 3188405 BCB03_000625 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P09 compound treatment 202630.0 -249000.0 -2.12 183560.0 -245000.0 -2.08 -2.9701 -1.0 3071652 BCB03_000626 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P10 compound treatment 300960.0 -151000.0 -1.28 236650.0 -192000.0 -1.63 -2.0602 -0.993 3070929 BCB03_000627 COCC1=C2[C@@H](CCc3ccccc3)OB(O)C[C@@H]2[C@H]4[C@@H](C1)C(=O)N(C)C4=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P11 mock treatment 364260.0 -87500.0 -0.74 264320.0 -165000.0 -1.4 -1.5134 -0.9567 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P12 mock treatment 344010.0 -108000.0 -0.92 345250.0 -83600.0 -0.71 -1.1498 -0.9919 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P13 compound treatment 134800.0 -317000.0 -2.7 124750.0 -304000.0 -2.58 -3.7309 -0.9998 3071653 BCB03_000628 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@@H]2C(=O)[C@@]43CO4)I 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P14 compound treatment 244340.0 -207000.0 -1.76 228500.0 -200000.0 -1.7 -2.4497 -0.9998 3188406 BCB03_000629 CN1C(=O)[C@@H]2CC(=C3[C@@H](CCc4ccccc4)OB(O)C[C@@H]3[C@@H]2C1=O)COc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P15 compound treatment 220290.0 -232000.0 -1.97 204860.0 -224000.0 -1.9 -2.7361 -0.9998 3188268 BCB03_000630 CCCCO[C@H]1C[C@H]2C(=C[C@]1(CO)C(=O)[C@@]32CO3)Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P16 compound treatment 286590.0 -165000.0 -1.41 282910.0 -146000.0 -1.24 -1.8691 -0.998 3070998 BCB03_000631 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P17 compound treatment 91050.0 -361000.0 -3.07 96080.0 -333000.0 -2.82 -4.1661 -0.9991 3071714 BCB03_000632 OC[C@@]1(C=C(Br)[C@@H]2C[C@@H]1c3ccccc3)C(=O)[C@@]42CO4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P18 compound treatment 243200.0 -209000.0 -1.77 235170.0 -194000.0 -1.64 -2.4165 -0.9993 3188793 BCB03_000633 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P19 compound treatment 150040.0 -302000.0 -2.57 142640.0 -286000.0 -2.43 -3.5319 -0.9996 3071715 BCB03_000634 Cc1cccc(c1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P20 compound treatment 184020.0 -268000.0 -2.28 244640.0 -184000.0 -1.56 -2.7157 -0.9831 3071118 BCB03_000635 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(C)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P21 compound treatment 157150.0 -295000.0 -2.51 163680.0 -265000.0 -2.25 -3.363 -0.9985 3071717 BCB03_000636 COc1ccc(cc1)[C@H]2C[C@H]3C(=C[C@]2(CO)C(=O)[C@@]43CO4)Br 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P22 compound treatment 146560.0 -305000.0 -2.6 269390.0 -159000.0 -1.35 -2.7926 -0.9538 3071120 BCB03_000637 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P23 compound treatment 114170.0 -338000.0 -2.87 87540.0 -341000.0 -2.9 -4.0782 -1.0 3071720 BCB03_000638 BrC1=C[C@]23COC[C@H]3C[C@@H]1[C@@]4(CO4)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2282 P24 compound treatment 210410.0 -241000.0 -2.05 280700.0 -148000.0 -1.26 -2.3407 -0.9722 3188808 BCB03_000639 CC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A01 compound treatment 438730.0 18400.0 0.16 428090.0 28900.0 0.25 0.2843 0.9768 3188923 BCB03_000640 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A02 compound treatment 284580.0 -136000.0 -1.15 451100.0 51900.0 0.44 -0.505 -0.4087 3563114 BCB03_000641 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)c3ccccc3C=C1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A03 compound treatment 295840.0 -124000.0 -1.06 336320.0 -62900.0 -0.53 -1.1257 -0.9496 3071127 BCB03_000642 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)CCc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A04 compound treatment 440290.0 20000.0 0.17 417980.0 18800.0 0.16 0.233 0.9995 3563115 BCB03_000643 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C)c4ccccc24 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A05 compound treatment 435040.0 14800.0 0.13 221280.0 -178000.0 -1.51 -0.9784 -0.6461 3071425 BCB03_000644 CCCC[C@@H](O)C1=C(C)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A06 compound treatment 323420.0 -96900.0 -0.82 306940.0 -92300.0 -0.78 -1.1361 -0.9997 3563116 BCB03_000645 COc1ccc(CN/2C(C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A07 compound treatment 212880.0 -207000.0 -1.76 240160.0 -159000.0 -1.35 -2.2016 -0.9912 3215868 BCB03_000646 CCCC[C@@H](O)C1=C(COC)Cn2n([C@H]1CO)c(=O)n(c3ccccc3)c2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A08 compound treatment 299100.0 -121000.0 -1.03 365860.0 -33300.0 -0.28 -0.9289 -0.8689 3563118 BCB03_000647 COc1ccc(CN2CCc3ccccc3C2C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A09 compound treatment 376410.0 -43900.0 -0.37 358800.0 -40400.0 -0.34 -0.5062 -0.9991 3215866 BCB03_000648 CCCC[C@@H](O)C1=C(COc2ccccc2)Cn3n([C@H]1CO)c(=O)n(c4ccccc4)c3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A10 compound treatment 320800.0 -99500.0 -0.85 238530.0 -161000.0 -1.36 -1.5622 -0.9737 3563119 BCB03_000649 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)c3ccccc3C=C1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A11 compound treatment 437120.0 16800.0 0.14 422490.0 23300.0 0.2 0.241 0.9875 3070999 BCB03_000650 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A12 compound treatment 417760.0 -2530.0 -0.02 267370.0 -132000.0 -1.12 -0.8059 -0.7206 3563120 BCB03_000651 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C=C)c4ccccc24 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A13 mock treatment 404320.0 -16000.0 -0.14 192850.0 -206000.0 -1.75 -1.3337 -0.7597 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A14 mock treatment 258990.0 -161000.0 -1.37 305480.0 -93700.0 -0.79 -1.5324 -0.9663 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A15 compound treatment 245280.0 -175000.0 -1.49 321050.0 -78100.0 -0.66 -1.5215 -0.9336 3071000 BCB03_000652 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)CCc3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A16 compound treatment 372590.0 -47700.0 -0.41 340070.0 -59100.0 -0.5 -0.6416 -0.9945 3563121 BCB03_000653 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A17 compound treatment 428240.0 7950.0 0.07 408730.0 9540.0 0.08 0.105 0.996 3188676 BCB03_000654 CCCC[C@@H](O)C1=C(C)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A18 compound treatment 401280.0 -19000.0 -0.16 335390.0 -63800.0 -0.54 -0.497 -0.8799 3563123 BCB03_000655 COc1ccc(CN2CCc3ccccc3C2C=C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A19 compound treatment 384480.0 -35800.0 -0.3 402740.0 3550.0 0.03 -0.1941 -0.6342 3188677 BCB03_000656 CCCC[C@@H](O)C1=C(COC)C[C@@H]2[C@H]([C@H]1CO)C(=O)N(Cc3ccccc3)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A20 compound treatment 385850.0 -34400.0 -0.29 292560.0 -107000.0 -0.9 -0.8468 -0.8906 3563124 BCB03_000657 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C3CC3)c4ccccc4C=C1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A21 compound treatment 273570.0 -147000.0 -1.25 362410.0 -36800.0 -0.31 -1.1032 -0.8575 3188788 BCB03_000658 CCCC[C@@H](O)C1=C(COc2ccccc2)C[C@@H]3[C@H]([C@H]1CO)C(=O)N(Cc4ccccc4)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A22 compound treatment 366640.0 -53600.0 -0.46 280870.0 -118000.0 -1.0 -1.0324 -0.9364 3563125 BCB03_000659 CCOC(=O)C1=C2C(ON1)N(Cc3ccc(OC)cc3)C(C4CC4)c5ccccc25 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A23 compound treatment 347480.0 -72800.0 -0.62 330720.0 -68500.0 -0.58 -0.8487 -0.9995 3071005 BCB03_000660 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 A24 compound treatment 349210.0 -71100.0 -0.6 304370.0 -94800.0 -0.8 -0.9963 -0.9901 3563121 BCB03_000661 COc1ccc(CN/2C(C=C)c3ccccc3C\C2=N\P(=O)(Oc4ccccc4)Oc5ccccc5)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B01 compound treatment 422080.0 1790.0 0.02 445160.0 46000.0 0.39 0.2865 0.7342 3216005 BCB03_000662 CN1C(=O)[C@@H]2C[C@]/3(C)OC[C@H]([C@@H]2C1=O)\C3=C/c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B02 compound treatment 419390.0 -897.0 -0.01 409250.0 10100.0 0.09 0.0549 0.6413 3614372 BCB03_000663 CCCNc1ncnc2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B03 compound treatment 401940.0 -18300.0 -0.16 280570.0 -119000.0 -1.01 -0.8219 -0.8071 3216013 BCB03_000664 CN1C(=O)[C@@H]2C[C@]/3(COc4ccccc4)OC[C@H]([C@@H]2C1=O)\C3=C/c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B04 compound treatment 404920.0 -15400.0 -0.13 423810.0 24600.0 0.21 0.0552 0.2241 3614373 BCB03_000665 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B05 compound treatment 392070.0 -28200.0 -0.24 382440.0 -16800.0 -0.14 -0.2702 -0.9687 3614374 BCB03_000666 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCc6cccc(Cl)c6)c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B06 compound treatment 365600.0 -54700.0 -0.47 380700.0 -18500.0 -0.16 -0.4399 -0.896 3614376 BCB03_000667 CC(C)(C)OC(=O)NCCOCCOCCNC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B07 compound treatment 357600.0 -62700.0 -0.53 336040.0 -63200.0 -0.54 -0.7559 -1.0 3614378 BCB03_000668 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5cccc(COC(=O)NCC#C)c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B08 compound treatment 412510.0 -7780.0 -0.07 395120.0 -4070.0 -0.03 -0.0712 -0.9541 3614380 BCB03_000669 Oc1ccc2ncnc(NCc3ccccc3)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B09 compound treatment 496060.0 75800.0 0.64 341760.0 -57400.0 -0.49 0.1113 0.1378 3614381 BCB03_000670 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B10 compound treatment 160680.0 -260000.0 -2.21 168870.0 -230000.0 -1.95 -2.9432 -0.9981 3614383 BCB03_000671 ONC(=O)/C=C/c1ccc(OCCc2cccs2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B11 compound treatment 459680.0 39400.0 0.34 469410.0 70200.0 0.6 0.6581 0.963 3614385 BCB03_000672 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B12 compound treatment 244320.0 -176000.0 -1.5 219430.0 -180000.0 -1.52 -2.1368 -1.0 3614386 BCB03_000673 ONC(=O)/C=C/c1ccc(OCc2ccc-3c(Cc4ccccc43)c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B13 mock treatment 454960.0 34700.0 0.29 453600.0 54400.0 0.46 0.5349 0.9766 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B14 mock treatment 420190.0 -97.4 0.0 382650.0 -16500.0 -0.14 -0.0998 -0.7113 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B15 compound treatment 414310.0 -5980.0 -0.05 368570.0 -30600.0 -0.26 -0.2196 -0.8298 3614388 BCB03_000674 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B16 compound treatment 127210.0 -293000.0 -2.49 139460.0 -260000.0 -2.2 -3.3209 -0.9981 3614389 BCB03_000675 ONC(=O)/C=C/c1ccc(OCc2ccccc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B17 compound treatment 431200.0 10900.0 0.09 248960.0 -150000.0 -1.27 -0.8355 -0.6539 3614391 BCB03_000676 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@@H](CO)NC(=O)N[C@@H](Cc7ccccc7)c8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B18 compound treatment 125530.0 -295000.0 -2.51 165190.0 -234000.0 -1.98 -3.1767 -0.9933 3614392 BCB03_000677 ONC(=O)/C=C/c1ccc(OCc2ccc(Cl)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B19 compound treatment 397960.0 -22300.0 -0.19 468800.0 69600.0 0.59 0.2832 0.4566 3556401 BCB03_000678 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B20 compound treatment 143390.0 -277000.0 -2.36 148920.0 -250000.0 -2.12 -3.1669 -0.9987 3614394 BCB03_000679 Nc1cccc(COc2ccc(/C=C/C(=O)NO)cc2)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B21 compound treatment 451430.0 31100.0 0.26 401080.0 1890.0 0.02 0.1987 0.7485 3556405 BCB03_000680 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B22 compound treatment 151740.0 -269000.0 -2.28 156500.0 -243000.0 -2.06 -3.0712 -0.9986 3614396 BCB03_000681 ONC(=O)/C=C/c1ccc(OCCCc2ccccc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B23 compound treatment 371360.0 -48900.0 -0.42 459940.0 60700.0 0.52 0.0701 0.1058 3556409 BCB03_000682 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 B24 compound treatment 159710.0 -261000.0 -2.22 172820.0 -226000.0 -1.92 -2.9253 -0.9974 3614398 BCB03_000683 ONC(=O)/C=C/c1ccc(OCCCCc2ccccc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C01 compound treatment 391220.0 -29100.0 -0.25 392560.0 -6630.0 -0.06 -0.2146 -0.8464 3188790 BCB03_000684 COCC1=C([C@H](O)CCc2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C02 compound treatment 377000.0 -43300.0 -0.37 388680.0 -10500.0 -0.09 -0.3235 -0.8537 3563126 BCB03_000685 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C)C=C(C)C=C1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C03 compound treatment 376800.0 -43500.0 -0.37 390360.0 -8830.0 -0.07 -0.3146 -0.8334 3188791 BCB03_000686 CN1C(=O)[C@@H]2CC(=C([C@H](O)CCc3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C04 compound treatment 398880.0 -21400.0 -0.18 396200.0 -2990.0 -0.03 -0.1467 -0.7979 3563127 BCB03_000687 COc1ccc(CN/2C(C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C05 compound treatment 398170.0 -22100.0 -0.19 323100.0 -76100.0 -0.65 -0.5895 -0.8767 3071437 BCB03_000688 OB1OC(CCc2ccccc2)CC=C1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C06 compound treatment 394110.0 -26200.0 -0.22 401170.0 1980.0 0.02 -0.1456 -0.652 3563129 BCB03_000689 COc1ccc(CN2C(C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C07 compound treatment 437540.0 17300.0 0.15 414200.0 15000.0 0.13 0.1938 0.9975 3071483 BCB03_000690 COC(=O)c1ccc(OC)c(/C=C\CC(OC(=O)c2ccncc2)c3ccccc3)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C08 compound treatment 455090.0 34800.0 0.3 399360.0 168.0 0.0 0.2104 0.7105 3563130 BCB03_000691 COc1ccc(CN2CCC(=CC2C)C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C09 compound treatment 428190.0 7900.0 0.07 341960.0 -57200.0 -0.49 -0.2958 -0.6034 3071486 BCB03_000692 CC(=O)OC(C/C=C\B1OC(C)(C)C(C)(C)O1)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C10 compound treatment 363700.0 -56600.0 -0.48 356870.0 -42300.0 -0.36 -0.5943 -0.9896 3563131 BCB03_000693 COC(=O)C1=CN(Cc2ccc(OC)cc2)C(C=C)C=C(C)C=C1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C11 mock treatment 433890.0 13600.0 0.12 424060.0 24900.0 0.21 0.231 0.96 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C12 mock treatment 419600.0 -687.0 -0.01 227420.0 -172000.0 -1.46 -1.0345 -0.7099 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C13 compound treatment 5120.0 -415000.0 -3.53 4800.0 -394000.0 -3.35 -4.8631 -0.9996 3188011 BCB03_000694 O=C1C=C(C(=O)c2ccc(cc12)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C14 compound treatment 382320.0 -38000.0 -0.32 269350.0 -130000.0 -1.1 -1.0072 -0.8775 3563132 BCB03_000695 COc1ccc(CN/2C(C=C)C=C(C)C\C2=N\P(=O)(Oc3ccccc3)Oc4ccccc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C15 mock treatment 355040.0 -65200.0 -0.56 328200.0 -71000.0 -0.6 -0.8183 -0.9992 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C16 mock treatment 376550.0 -43700.0 -0.37 319280.0 -79900.0 -0.68 -0.7424 -0.9601 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C17 compound treatment 7890.0 -412000.0 -3.51 9760.0 -389000.0 -3.3 -4.8167 -0.9995 3071579 BCB03_000696 O=C1C=C(C(=O)C2=C1CC(=CC2)[C@H]3Oc4ccccc4S(=O)(=O)N5CCC[C@@H]35)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C18 compound treatment 400800.0 -19500.0 -0.17 391080.0 -8110.0 -0.07 -0.1659 -0.9242 3563134 BCB03_000697 COc1ccc(CN2C(C=C)C3C4C(C2C=C3C)C(=O)N(C)C4=O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C19 compound treatment 212420.0 -208000.0 -1.77 249660.0 -150000.0 -1.27 -2.1474 -0.9867 3070932 BCB03_000698 OCC(NC(=O)OCC1c2ccccc2-c3ccccc13)C=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C20 compound treatment 342240.0 -78000.0 -0.66 341450.0 -57700.0 -0.49 -0.8158 -0.9888 3563135 BCB03_000699 COc1ccc(CN2CCC(=CC2C=C)C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C21 compound treatment 353350.0 -66900.0 -0.57 391890.0 -7300.0 -0.06 -0.4465 -0.7794 3188522 BCB03_000700 COc1ccc(CN([C@H](COC(=O)OC(C)(C)C)C=C)S(=O)(=O)c2ccc(Br)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C22 compound treatment 438790.0 18500.0 0.16 399360.0 168.0 0.0 0.1123 0.7135 1025568 BCB03_000701 COc1cc2CCN(C)C(C)c2cc1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C23 compound treatment 407520.0 -12800.0 -0.11 406950.0 7760.0 0.07 -0.0303 -0.2384 3070934 BCB03_000702 CC(=O)OCC(NS(=O)(=O)c1ccc(Br)cc1)C=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 C24 compound treatment 393120.0 -27200.0 -0.23 375360.0 -23800.0 -0.2 -0.3064 -0.9978 3563136 BCB03_000703 COc1cc2CCN(C)C(C=C)c2cc1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D01 compound treatment 403690.0 -16600.0 -0.14 443250.0 44100.0 0.37 0.1644 0.4116 3556407 BCB03_000704 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D02 compound treatment 86410.0 -334000.0 -2.84 91400.0 -308000.0 -2.61 -3.8547 -0.9991 3614403 BCB03_000705 ONC(=O)/C=C/c1ccc(OCCn2c3ccccc3c4ccccc24)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D03 compound treatment 444990.0 24700.0 0.21 431300.0 32100.0 0.27 0.3412 0.9918 3556412 BCB03_000706 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D04 compound treatment 324410.0 -95900.0 -0.82 210450.0 -189000.0 -1.6 -1.7089 -0.951 3614405 BCB03_000707 Cc1cccc(Cl)c1NC(=O)C2=CC=C(Cl)C2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D05 compound treatment 457480.0 37200.0 0.32 358980.0 -40200.0 -0.34 -0.0175 -0.0375 3614406 BCB03_000708 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D06 compound treatment 135700.0 -285000.0 -2.42 135580.0 -264000.0 -2.24 -3.2931 -0.9992 3614408 BCB03_000709 COc1ccc(CN(C(=O)C2=CC=C(Cl)C2)c3c(C)cccc3Cl)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D07 compound treatment 400380.0 -19900.0 -0.17 302240.0 -97000.0 -0.82 -0.7013 -0.8352 3614409 BCB03_000710 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D08 compound treatment 312380.0 -108000.0 -0.92 307600.0 -91600.0 -0.78 -1.1985 -0.9966 3614410 BCB03_000711 COc1ccc(CN(C(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3)c4c(C)cccc4Cl)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D09 compound treatment 411540.0 -8750.0 -0.07 441620.0 42400.0 0.36 0.2019 0.5493 3614411 BCB03_000712 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D10 compound treatment 252170.0 -168000.0 -1.43 238400.0 -161000.0 -1.36 -1.9758 -0.9997 3614412 BCB03_000713 Cc1cccc(Cl)c1NC(=O)C2=CC=C(C2)Nc3cc(Cl)nc(C)n3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D11 mock treatment 380820.0 -39500.0 -0.34 425560.0 26400.0 0.22 -0.0793 -0.1965 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D12 mock treatment 409150.0 -11100.0 -0.09 335300.0 -63900.0 -0.54 -0.4502 -0.8183 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D13 compound treatment 380830.0 -39500.0 -0.34 441630.0 42400.0 0.36 0.0172 0.0349 3614413 BCB03_000714 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC(=O)c6oc(CC[C@H](CO)NC(=O)N[C@@H](Cc7ccccc7)C(=O)NCc8cn(C[C@H](Cc9ccccc9)NC2=O)nn8)c(C(=O)OC)c6C(=O)OC)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D14 compound treatment 164970.0 -255000.0 -2.17 139120.0 -260000.0 -2.21 -3.0958 -1.0 3614414 BCB03_000715 Cc1cccc(Cl)c1NC(=O)c2cnc(Nc3cc(nc(C)n3)N4CCN(CCO)CC4)s2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D15 mock treatment 402950.0 -17300.0 -0.15 431760.0 32600.0 0.28 0.0911 0.2907 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D16 mock treatment 442460.0 22200.0 0.19 423130.0 23900.0 0.2 0.277 0.9993 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D17 compound treatment 411690.0 -8600.0 -0.07 363940.0 -35300.0 -0.3 -0.2632 -0.8549 3556423 BCB03_000716 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D18 compound treatment 231100.0 -189000.0 -1.61 180600.0 -219000.0 -1.85 -2.4492 -0.9975 3614415 BCB03_000717 COC(=O)C1(CCCC1)C2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)CCO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D19 compound treatment 381390.0 -38900.0 -0.33 379520.0 -19700.0 -0.17 -0.352 -0.9498 3556419 BCB03_000718 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D20 compound treatment 337710.0 -82600.0 -0.7 264690.0 -135000.0 -1.14 -1.3035 -0.9729 3614418 BCB03_000719 Cn1c(=O)n2[C@H]3[C@@H]4[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc5ccccc5)N4CC3=C[C@@H](C6CC6)n2c1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D21 compound treatment 389760.0 -30500.0 -0.26 270680.0 -129000.0 -1.09 -0.9545 -0.8517 3614420 BCB03_000720 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D22 compound treatment 286770.0 -134000.0 -1.14 245150.0 -154000.0 -1.31 -1.7272 -0.9976 3614421 BCB03_000721 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CCCC=C[C@H]4[C@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D23 compound treatment 235410.0 -185000.0 -1.57 211080.0 -188000.0 -1.6 -2.2405 -1.0 3614424 BCB03_000722 COC(=O)c1cn(CC(=O)N2CCC3(CC2)N(CNC3=O)c4ccccc4)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 D24 compound treatment 7810.0 -412000.0 -3.51 8120.0 -391000.0 -3.32 -4.827 -0.9996 3614425 BCB03_000723 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E01 mock treatment 469550.0 49300.0 0.42 477920.0 78700.0 0.67 0.7686 0.9748 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E02 mock treatment 457150.0 36900.0 0.31 406660.0 7470.0 0.06 0.2665 0.8331 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E03 compound treatment 443520.0 23200.0 0.2 434730.0 35500.0 0.3 0.3529 0.979 3070935 BCB03_000724 O=C(CCCCCCC(=O)Nc1ccccc1)N/N=C/c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E04 compound treatment 392160.0 -28100.0 -0.24 289060.0 -110000.0 -0.93 -0.8298 -0.8604 3563137 BCB03_000725 COc1cc2CCN(C)C(C3CC3)c2cc1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E05 compound treatment 439210.0 18900.0 0.16 309760.0 -89400.0 -0.76 -0.4226 -0.5449 3070936 BCB03_000726 C/C(=N\O)/C(=O)NCCCCCNC(=O)OCc1ccccc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E06 compound treatment 458010.0 37700.0 0.32 436380.0 37200.0 0.32 0.45 1.0 3563138 BCB03_000727 COCC#CC1N(C)CCc2cc(OC)c(OC)cc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E07 compound treatment 452350.0 32100.0 0.27 441290.0 42100.0 0.36 0.4454 0.9912 3070944 BCB03_000728 O/N=C(\Cc1ccccc1)/C(=O)NCCCCCNC(=O)OCc2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E08 compound treatment 426500.0 6210.0 0.05 348710.0 -50500.0 -0.43 -0.2654 -0.6152 3562035 BCB03_000729 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E09 mock treatment 457370.0 37100.0 0.32 484960.0 85800.0 0.73 0.7375 0.93 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E10 mock treatment 477080.0 56800.0 0.48 444500.0 45300.0 0.38 0.6134 0.9936 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E11 compound treatment 336530.0 -83800.0 -0.71 260570.0 -139000.0 -1.18 -1.3353 -0.9712 3188539 BCB03_000730 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccccc4)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E12 compound treatment 232830.0 -187000.0 -1.59 277640.0 -122000.0 -1.03 -1.8568 -0.9777 3563139 BCB03_000731 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E13 compound treatment 447680.0 27400.0 0.23 340000.0 -59200.0 -0.5 -0.1903 -0.3437 3188540 BCB03_000732 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccccc4)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E14 compound treatment 222160.0 -198000.0 -1.69 209120.0 -190000.0 -1.61 -2.3319 -0.9998 3563140 BCB03_000733 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C=C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E15 compound treatment 392400.0 -27900.0 -0.24 430190.0 31000.0 0.26 0.0182 0.0513 3188541 BCB03_000734 C[C@@H]1ON([C@@H]([C@H]1C(=O)O)c2ccccc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E16 compound treatment 184730.0 -236000.0 -2.0 191810.0 -207000.0 -1.76 -2.6609 -0.9979 3563141 BCB03_000735 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2C4CC4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E17 mock treatment 468400.0 48100.0 0.41 366910.0 -32300.0 -0.27 0.0958 0.1945 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E18 mock treatment 431040.0 10800.0 0.09 340530.0 -58700.0 -0.5 -0.2872 -0.5676 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E19 compound treatment 394960.0 -25300.0 -0.22 377770.0 -21400.0 -0.18 -0.2809 -0.9964 3070947 BCB03_000736 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E20 compound treatment 375040.0 -45200.0 -0.38 441470.0 42300.0 0.36 -0.0186 -0.0353 3563142 BCB03_000737 COCC#CC1N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E21 compound treatment 334620.0 -85700.0 -0.73 422850.0 23700.0 0.2 -0.3734 -0.494 3188544 BCB03_000738 C[C@H]1ON([C@H]([C@@H]1C(=O)N2[C@H](COC2=O)c3ccccc3)c4ccc(O)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E22 compound treatment 360640.0 -59600.0 -0.51 363370.0 -35800.0 -0.3 -0.5737 -0.9699 3563143 BCB03_000739 COc1cc2CCN(C)C(C)(C)c2cc1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E23 compound treatment 433540.0 13300.0 0.11 447320.0 48100.0 0.41 0.3684 0.8698 3188657 BCB03_000740 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5cccc(c5)C(=O)OC(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 E24 compound treatment 338880.0 -81400.0 -0.69 329000.0 -70200.0 -0.6 -0.9107 -0.9972 3563144 BCB03_000741 COc1cc2CCN(C)C(C)(C=C)c2cc1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F01 mock treatment 478630.0 58300.0 0.5 421360.0 22200.0 0.19 0.4839 0.9118 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F02 mock treatment 467050.0 46800.0 0.4 400170.0 978.0 0.01 0.2872 0.7217 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F03 compound treatment 392170.0 -28100.0 -0.24 402910.0 3720.0 0.03 -0.1468 -0.6086 3614432 BCB03_000742 COC(=O)c1cn(C[C@@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F04 compound treatment 394200.0 -26100.0 -0.22 271690.0 -128000.0 -1.08 -0.9217 -0.8348 3614434 BCB03_000743 COC(=O)[C@H](Cc1ccccc1)N[C@H](/C=C/C2CC2)[C@@H](O)CCN=[N+]=[N-] 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F05 compound treatment 411630.0 -8660.0 -0.07 432060.0 32900.0 0.28 0.1451 0.5031 3614437 BCB03_000744 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)c3ccccc3)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F06 compound treatment 329560.0 -90700.0 -0.77 215620.0 -184000.0 -1.56 -1.6469 -0.9476 3614440 BCB03_000745 [N-]=[N+]=NCC[C@@H]1OC(=O)[C@H](Cc2ccccc2)N(CC#C)[C@@H]1/C=C/C3CC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F07 compound treatment 361230.0 -59100.0 -0.5 412860.0 13700.0 0.12 -0.2733 -0.53 3614442 BCB03_000746 COC(=O)c1cn(CCCNC(=S)Nc2ccc(cc2)[N+](=O)[O-])nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F08 compound treatment 448480.0 28200.0 0.24 466740.0 67500.0 0.57 0.5748 0.9253 3614443 BCB03_000747 C=C/C=C/[C@H]1[C@@H]2[C@H](CCN=[N+]=[N-])OC(=O)[C@H](Cc3ccccc3)N2CC1=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F09 mock treatment 493000.0 72700.0 0.62 322250.0 -76900.0 -0.65 -0.0241 -0.0268 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F10 mock treatment 424400.0 4110.0 0.03 437150.0 38000.0 0.32 0.2524 0.7794 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F11 compound treatment 455170.0 34900.0 0.3 330010.0 -69200.0 -0.59 -0.2051 -0.3119 3614446 BCB03_000748 COC(=O)c1cn(CCCNC(=O)Nc2ccccc2)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F12 compound treatment 372380.0 -47900.0 -0.41 280350.0 -119000.0 -1.01 -1.001 -0.9206 3614447 BCB03_000749 COC(=O)[C@H](Cc1ccccc1)N2C[C@](C)(OC(C)C)O[C@@H](CCN=[N+]=[N-])[C@H]2/C=C/C3CC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F13 compound treatment 361680.0 -58600.0 -0.5 274960.0 -124000.0 -1.05 -1.0977 -0.9416 3614451 BCB03_000750 COC(=O)c1cn(CCNC(=O)Nc2ccccc2)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F14 compound treatment 361350.0 -58900.0 -0.5 334080.0 -65100.0 -0.55 -0.7451 -0.9988 3614452 BCB03_000751 COC(=O)C1(CCCC1)C2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)CCO)c(=O)n(C)c5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F15 compound treatment 355850.0 -64400.0 -0.55 352320.0 -46900.0 -0.4 -0.6688 -0.9876 3614455 BCB03_000752 COC(=O)c1cn(CCCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F16 compound treatment 148120.0 -272000.0 -2.32 138080.0 -261000.0 -2.21 -3.2034 -0.9998 3614458 BCB03_000753 OCC[C@@H]1OC(=O)C2(CCCC2)N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@H]13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F17 mock treatment 411260.0 -9030.0 -0.08 441150.0 42000.0 0.36 0.1974 0.5421 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F18 mock treatment 438910.0 18600.0 0.16 387070.0 -12100.0 -0.1 0.0393 0.2082 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F19 compound treatment 288210.0 -132000.0 -1.12 422320.0 23100.0 0.2 -0.6558 -0.5749 3614462 BCB03_000754 COC(=O)c1cn(CCNC(=O)[C@H](Cc2ccccc2)NS(=O)(=O)c3ccc(C)cc3)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F20 compound treatment 410180.0 -10100.0 -0.09 342210.0 -57000.0 -0.48 -0.4026 -0.82 3563105 BCB03_000755 COC(=O)C1=CN(C)C(C=C)c2ccccc2C=C1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F21 compound treatment 407920.0 -12400.0 -0.11 352290.0 -46900.0 -0.4 -0.3557 -0.8644 3614464 BCB03_000756 COC(=O)c1cn(CCNC(=O)[C@@H](NS(=O)(=O)c2ccc(C)cc2)C(C)C)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F22 compound treatment 446560.0 26300.0 0.22 314490.0 -84700.0 -0.72 -0.35 -0.4652 3563108 BCB03_000757 COC(=O)C1=CN(C)C(C2CC2)c3ccccc3C=C1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F23 compound treatment 435910.0 15600.0 0.13 367630.0 -31600.0 -0.27 -0.0953 -0.319 3614467 BCB03_000758 COC(=O)c1cn(C[C@@H]2CCCN2S(=O)(=O)c3ccc(C)cc3)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 F24 compound treatment 355070.0 -65200.0 -0.55 423290.0 24100.0 0.2 -0.2478 -0.419 3188926 BCB03_000759 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(nc5)C(F)(F)F)C(C)(C)C4CC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G01 compound treatment 430990.0 10700.0 0.09 511690.0 112000.0 0.95 0.7392 0.7711 3188658 BCB03_000760 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(Br)cc4)c5ccc(cc5)C(=O)OC(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G02 compound treatment 433440.0 13200.0 0.11 461500.0 62300.0 0.53 0.4529 0.8382 3563145 BCB03_000761 COCC#CC1(C)N(C)CCc2cc(OC)c(OC)cc21 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G03 mock treatment 423310.0 3020.0 0.03 473510.0 74300.0 0.63 0.464 0.7353 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G04 mock treatment 455730.0 35400.0 0.3 450840.0 51600.0 0.44 0.523 0.9834 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G05 compound treatment 420370.0 82.6 0.0 338160.0 -61000.0 -0.52 -0.3656 -0.7061 3188659 BCB03_000762 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4cccc(NC(=O)OCC5c6ccccc6-c7ccccc57)c4)c8ccc(I)cc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G06 compound treatment 434320.0 14000.0 0.12 450580.0 51400.0 0.44 0.3926 0.8688 3563146 BCB03_000763 COc1ccc(C[N+]2=C(C)c3cc(OC)c(OC)cc3CC2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G07 compound treatment 395920.0 -24400.0 -0.21 358590.0 -40600.0 -0.34 -0.3901 -0.9705 3188672 BCB03_000764 C[C@@H]1ON([C@@H]([C@H]1C(=O)N2[C@H](Cc3ccccc3)COC2=O)c4ccc(OC(=O)OC(C)(C)C)cc4)c5ccc(I)cc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G08 compound treatment 400390.0 -19900.0 -0.17 448080.0 48900.0 0.41 0.1735 0.3874 3563147 BCB03_000765 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G09 compound treatment 464640.0 44400.0 0.38 468530.0 69300.0 0.59 0.6827 0.977 3188673 BCB03_000766 COC(=O)CCCCCCC(=O)Nc1ccc(NC(=O)CCCC[P+](c2ccccc2)(c3ccccc3)c4ccccc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G10 compound treatment 433440.0 13200.0 0.11 419200.0 20000.0 0.17 0.1991 0.9796 3563148 BCB03_000767 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C=C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G11 compound treatment 419610.0 -677.0 -0.01 350640.0 -48600.0 -0.41 -0.2953 -0.7169 3188674 BCB03_000768 CC(C)[C@H]1COC(=O)N1C(=O)[C@@H]2[C@@H](C)ON([C@@H]2c3ccccc3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G12 compound treatment 243110.0 -177000.0 -1.51 150780.0 -248000.0 -2.11 -2.5558 -0.9865 3563149 BCB03_000769 COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2(C)C4CC4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G13 compound treatment 360730.0 -59600.0 -0.51 258110.0 -141000.0 -1.2 -1.2045 -0.9268 3188675 BCB03_000770 CC(C)[C@@H](CO)NC(=O)[C@@H]1[C@@H](C)ON([C@@H]1c2ccccc2)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G14 compound treatment 458270.0 38000.0 0.32 391280.0 -7910.0 -0.07 0.181 0.5485 3563150 BCB03_000771 COCC#CC1(C)N(Cc2ccc(OC)cc2)CCc3cc(OC)c(OC)cc31 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G15 compound treatment 398650.0 -21600.0 -0.18 361560.0 -37600.0 -0.32 -0.3559 -0.9658 3071001 BCB03_000772 COC(=O)[C@@H]1N[C@H]2[C@@H](COc3ccccc23)[C@@H]1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G16 compound treatment 421300.0 1010.0 0.01 416610.0 17400.0 0.15 0.1106 0.7471 3563151 BCB03_000773 COc1cc2CC(C)N(C)C(C)c2cc1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G17 compound treatment 415600.0 -4690.0 -0.04 382930.0 -16300.0 -0.14 -0.1257 -0.8757 3071002 BCB03_000774 OCC1CC(=NO1)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G18 compound treatment 392380.0 -27900.0 -0.24 389930.0 -9260.0 -0.08 -0.2234 -0.8935 3563152 BCB03_000775 COc1cc2CC(C)N(C)C(C=C)c2cc1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G19 mock treatment 450560.0 30300.0 0.26 398740.0 -452.0 0.0 0.1794 0.6965 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G20 mock treatment 304690.0 -116000.0 -0.98 416010.0 16800.0 0.14 -0.5945 -0.5983 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G21 compound treatment 446050.0 25800.0 0.22 361350.0 -37800.0 -0.32 -0.072 -0.1853 3071004 BCB03_000776 O[C@H](C=C)[C@H]1CC(=NO1)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G22 compound treatment 390440.0 -29800.0 -0.25 340230.0 -59000.0 -0.5 -0.5332 -0.9506 3563153 BCB03_000777 COc1cc2CC(C)N(C)C(C3CC3)c2cc1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G23 compound treatment 450010.0 29700.0 0.25 378160.0 -21000.0 -0.18 0.0526 0.1701 3414065 BCB03_000778 O[C@@H]([C@H]1CC(=NO1)c2ccccc2)[C@@H]3CC(=NO3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 G24 compound treatment 404530.0 -15800.0 -0.13 340600.0 -58600.0 -0.5 -0.4462 -0.8668 3563154 BCB03_000779 COCC#CC1N(C)C(C)Cc2cc(OC)c(OC)cc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H01 compound treatment 477970.0 57700.0 0.49 486600.0 87400.0 0.74 0.8713 0.9799 3614478 BCB03_000780 COC(=O)c1cn(CC(=O)N2CCN(C)CC2)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H02 compound treatment 353950.0 -66300.0 -0.56 320070.0 -79100.0 -0.67 -0.8736 -0.9963 3061928 BCB03_000781 COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H03 mock treatment 491430.0 71100.0 0.61 409890.0 10700.0 0.09 0.4921 0.8041 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H04 mock treatment 478800.0 58500.0 0.5 274880.0 -124000.0 -1.05 -0.3937 -0.3376 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H05 compound treatment 220060.0 -200000.0 -1.7 214980.0 -184000.0 -1.56 -2.3094 -0.9991 3614479 BCB03_000782 CCOC(=O)[C@H](Cc1ccccc1)NC(=O)Cn2cc(nn2)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H06 compound treatment 243780.0 -177000.0 -1.5 184400.0 -215000.0 -1.82 -2.3502 -0.9954 3614483 BCB03_000783 COCCOc1cc2ncnc(Nc3cccc(C#C)c3)c2cc1OCCOC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H07 compound treatment 365230.0 -55100.0 -0.47 398310.0 -882.0 -0.01 -0.3365 -0.7183 3614485 BCB03_000784 COC(=O)[C@@H](NC(=O)Cn1cc(nn1)C(=O)OC)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H08 mock treatment 482800.0 62500.0 0.53 409220.0 10000.0 0.09 0.4362 0.8099 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H09 compound treatment 423550.0 3260.0 0.03 392090.0 -7100.0 -0.06 -0.023 -0.3463 3614488 BCB03_000785 CCOC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn3cc(nn3)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H10 mock treatment 273130.0 -147000.0 -1.25 376800.0 -22400.0 -0.19 -1.0195 -0.8052 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H11 compound treatment 486800.0 66500.0 0.57 403380.0 4190.0 0.04 0.4252 0.75 3614492 BCB03_000786 COC(=O)c1cn(nn1)c2cccc(N)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H12 mock treatment 442630.0 22300.0 0.19 170890.0 -228000.0 -1.94 -1.235 -0.6347 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H13 compound treatment 439320.0 19000.0 0.16 352750.0 -46400.0 -0.39 -0.1641 -0.3852 3614494 BCB03_000787 COC(=O)c1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H14 mock treatment 389480.0 -30800.0 -0.26 348960.0 -50200.0 -0.43 -0.4866 -0.9728 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H15 compound treatment 354210.0 -66100.0 -0.56 466080.0 66900.0 0.57 0.0037 0.0046 3614495 BCB03_000788 COC(=O)c1cn(CC(=O)N2CCOCC2)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H16 mock treatment 361710.0 -58600.0 -0.5 486530.0 87300.0 0.74 0.1715 0.1921 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H17 compound treatment 431840.0 11600.0 0.1 475630.0 76400.0 0.65 0.528 0.8051 3614498 BCB03_000789 COC(=O)c1cn(CC(=O)Nc2ccc(OC)c(OC)c2)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H18 mock treatment 399600.0 -20700.0 -0.18 406330.0 7140.0 0.06 -0.0816 -0.4386 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H19 mock treatment 437940.0 17700.0 0.15 426080.0 26900.0 0.23 0.2675 0.9794 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H20 mock treatment 451420.0 31100.0 0.26 450560.0 51400.0 0.44 0.4954 0.9715 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H21 compound treatment 384030.0 -36300.0 -0.31 433990.0 34800.0 0.3 -0.0094 -0.022 3614499 BCB03_000790 COC(=O)c1cn(CC(=O)Nc2cc(OC)ccc2OC)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H22 mock treatment 317880.0 -102000.0 -0.87 348500.0 -50700.0 -0.43 -0.9201 -0.947 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H23 compound treatment 433220.0 12900.0 0.11 433290.0 34100.0 0.29 0.2823 0.9123 3614501 BCB03_000791 COC(=O)c1cn(CC(=O)Nc2nccs2)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 H24 mock treatment 326410.0 -93900.0 -0.8 326000.0 -73200.0 -0.62 -1.0037 -0.9922 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I01 compound treatment 305840.0 -114000.0 -0.97 413940.0 14700.0 0.13 -0.6 -0.6112 3071008 BCB03_000792 CC[C@H](C)C(=O)O[C@H]1CC[C@@]2(C)C(CCC3=C2CC[C@]4(C)[C@H](CC[C@@]34C)[C@H](C)CCCC(C)C)C1(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I02 compound treatment 460750.0 40500.0 0.34 473600.0 74400.0 0.63 0.6897 0.9593 3563155 BCB03_000793 COc1ccc(C[N+]2=Cc3cc(OC)c(OC)cc3CC2C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I03 compound treatment 284960.0 -135000.0 -1.15 309550.0 -89600.0 -0.76 -1.3518 -0.9797 3188792 BCB03_000794 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)CCl)C(C)(C)C4CC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I04 compound treatment 384890.0 -35400.0 -0.3 318670.0 -80500.0 -0.68 -0.6959 -0.9323 3563156 BCB03_000795 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I05 mock treatment 377130.0 -43200.0 -0.37 338160.0 -61000.0 -0.52 -0.6257 -0.9858 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I06 mock treatment 441410.0 21100.0 0.18 376000.0 -23200.0 -0.2 -0.012 -0.0452 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I07 compound treatment 448720.0 28400.0 0.24 453840.0 54600.0 0.46 0.4988 0.954 3188805 BCB03_000796 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)C(C)(C)C)C(C)(C)C4CC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I08 compound treatment 218840.0 -201000.0 -1.71 204680.0 -195000.0 -1.65 -2.3785 -0.9998 3563157 BCB03_000797 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C=C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I09 compound treatment 382820.0 -37500.0 -0.32 425560.0 26400.0 0.22 -0.0672 -0.1726 3188806 BCB03_000798 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccccc5)C(C)(C)C4CC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I10 compound treatment 190080.0 -230000.0 -1.96 195490.0 -204000.0 -1.73 -2.6067 -0.9981 3563158 BCB03_000799 COc1ccc(CN2C(C)Cc3cc(OC)c(OC)cc3C2C4CC4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I11 compound treatment 403840.0 -16400.0 -0.14 511280.0 112000.0 0.95 0.5734 0.5966 3188807 BCB03_000800 COc1ccc(cc1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I12 compound treatment 267250.0 -153000.0 -1.3 212090.0 -187000.0 -1.59 -2.0429 -0.9952 3563159 BCB03_000801 COCC#CC1N(Cc2ccc(OC)cc2)C(C)Cc3cc(OC)c(OC)cc13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I13 compound treatment 431740.0 11500.0 0.1 368820.0 -30400.0 -0.26 -0.1133 -0.4113 3071124 BCB03_000802 COc1cccc(c1)C(=O)O[C@H]2CC[C@@]3(C)C(CCC4=C3CC[C@]5(C)[C@H](CC[C@@]45C)[C@H](C)CCCC(C)C)C2(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I14 compound treatment 313980.0 -106000.0 -0.9 279950.0 -119000.0 -1.01 -1.3547 -0.9984 3614506 BCB03_000803 CCCCOc1ccc(/C=C/C(=O)NO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I15 compound treatment 431860.0 11600.0 0.1 443090.0 43900.0 0.37 0.3329 0.8644 3188924 BCB03_000804 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(Br)cc5)C(C)(C)C4CC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I16 compound treatment 170780.0 -250000.0 -2.12 177010.0 -222000.0 -1.88 -2.8336 -0.9982 3614510 BCB03_000805 ONC(=O)/C=C/c1ccc(OC2CCCCC2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I17 compound treatment 457460.0 37200.0 0.32 443470.0 44300.0 0.38 0.4892 0.9963 3188925 BCB03_000806 CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]4(C)CC[C@H](OC(=O)c5ccc(N)cc5)C(C)(C)C4CC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I18 compound treatment 282590.0 -138000.0 -1.17 263280.0 -136000.0 -1.15 -1.6436 -1.0 3614513 BCB03_000807 COc1ccc(/C=C/C(=O)NO)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I19 compound treatment 445020.0 24700.0 0.21 365930.0 -33300.0 -0.28 -0.0507 -0.1441 3614517 BCB03_000808 COC(=O)[C@H](Cc1ccccc1)N(CC#C)O[C@@H](/C=C/[C@@H](O)Cc2ccccc2)C3CC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I20 compound treatment 239880.0 -180000.0 -1.53 256090.0 -143000.0 -1.21 -1.9436 -0.9933 3614521 BCB03_000809 ONC(=O)/C=C/c1ccc(O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I21 mock treatment 400830.0 -19500.0 -0.17 447800.0 48600.0 0.41 0.1745 0.3928 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I22 mock treatment 409950.0 -10300.0 -0.09 291530.0 -108000.0 -0.91 -0.708 -0.7716 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I23 compound treatment 233510.0 -187000.0 -1.59 193660.0 -206000.0 -1.74 -2.3564 -0.9989 3614524 BCB03_000810 COC(=O)[C@H](Cc1ccccc1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 I24 compound treatment 217520.0 -203000.0 -1.73 169690.0 -230000.0 -1.95 -2.5964 -0.9982 3614525 BCB03_000811 ONC(=O)/C=C/c1ccc(OCCc2ccccc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J01 compound treatment 428000.0 7710.0 0.07 445460.0 46300.0 0.39 0.3239 0.814 3614528 BCB03_000812 COC(=O)c1cn(CC(=O)Nc2ccon2)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J02 mock treatment 424030.0 3740.0 0.03 452650.0 53500.0 0.45 0.3432 0.7549 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J03 compound treatment 405000.0 -15300.0 -0.13 389070.0 -10100.0 -0.09 -0.1527 -0.9797 3614530 BCB03_000813 COC(=O)c1cn(C[C@H](Cc2ccccc2)NC(=O)Nc3ccccc3)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J04 mock treatment 250330.0 -170000.0 -1.45 284540.0 -115000.0 -0.97 -1.7101 -0.9814 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J05 mock treatment 213060.0 -207000.0 -1.76 194000.0 -205000.0 -1.74 -2.4774 -1.0 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J06 mock treatment 490530.0 70200.0 0.6 256450.0 -143000.0 -1.21 -0.4336 -0.3212 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J07 compound treatment 336580.0 -83700.0 -0.71 361890.0 -37300.0 -0.32 -0.7273 -0.9333 3614532 BCB03_000814 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCN(CC4)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J08 mock treatment 441760.0 21500.0 0.18 400890.0 1700.0 0.01 0.1394 0.7605 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J09 compound treatment 278240.0 -142000.0 -1.21 354400.0 -44800.0 -0.38 -1.1232 -0.8866 3614534 BCB03_000815 NC(=N)NCc1cn(CC(=O)N2CCN(CC2)c3ccccc3)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J10 mock treatment 472660.0 52400.0 0.45 435310.0 36100.0 0.31 0.5317 0.9833 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J11 compound treatment 464410.0 44100.0 0.38 370340.0 -28900.0 -0.24 0.0924 0.2061 3614535 BCB03_000816 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCN(CC3)c4ccccc4)nn2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J12 mock treatment 394110.0 -26200.0 -0.22 493600.0 94400.0 0.8 0.4088 0.4918 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J13 compound treatment 476750.0 56500.0 0.48 453570.0 54400.0 0.46 0.6658 0.9998 3614536 BCB03_000817 O=C(Cn1cc(nn1)C2(CCCCC2)NC(=O)Nc3ccccc3)N4CCOCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J14 mock treatment 440590.0 20300.0 0.17 475540.0 76300.0 0.65 0.5801 0.8654 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J15 compound treatment 377680.0 -42600.0 -0.36 429070.0 29900.0 0.25 -0.0771 -0.1743 3614537 BCB03_000818 CC(=O)Nc1ccccc1c2cn(CC(=O)N3CCOCC3)nn2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J16 mock treatment 480810.0 60500.0 0.51 394360.0 -4830.0 -0.04 0.3351 0.6488 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J17 compound treatment 426040.0 5750.0 0.05 382320.0 -16900.0 -0.14 -0.0666 -0.4403 3556424 BCB03_000819 COC(=O)c1c(C(=O)OC)c2oc1CC[C@H](CO)NC(=O)N[C@@H](Cc3ccccc3)C(=O)NCc4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J18 mock treatment 395110.0 -25200.0 -0.21 384350.0 -14800.0 -0.13 -0.2405 -0.9679 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J19 compound treatment 437680.0 17400.0 0.15 325630.0 -73600.0 -0.62 -0.3366 -0.5249 3614538 BCB03_000820 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCCn3cc(nn3)c4ccccc4N 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J20 mock treatment 479760.0 59500.0 0.51 376580.0 -22600.0 -0.19 0.2221 0.4105 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J21 mock treatment 443200.0 22900.0 0.19 333540.0 -65700.0 -0.56 -0.256 -0.4338 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J22 mock treatment 337250.0 -83000.0 -0.71 412080.0 12900.0 0.11 -0.4222 -0.5906 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J23 compound treatment 350690.0 -69600.0 -0.59 298490.0 -101000.0 -0.85 -1.0227 -0.984 3614540 BCB03_000821 Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)NCCn3cc(nn3)c4ccccc4N 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 J24 mock treatment 459550.0 39300.0 0.33 349860.0 -49300.0 -0.42 -0.0597 -0.1115 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K01 compound treatment 2560.0 -418000.0 -3.55 3390.0 -396000.0 -3.36 -4.887 -0.9996 3614545 BCB03_000822 COC(=O)[C@H](Cc1ccccc1)N2CC3=CC(=O)[C@H](C4CC4)[C@H]3[C@@H]2[C@@H](O)Cc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K02 compound treatment 192130.0 -228000.0 -1.94 188710.0 -210000.0 -1.79 -2.635 -0.9991 3614548 BCB03_000823 COc1ccc(CCCOc2ccc(/C=C/C(=O)NO)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K03 compound treatment 4960.0 -415000.0 -3.53 3520.0 -396000.0 -3.36 -4.8717 -0.9997 3614553 BCB03_000824 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)[C@@H]3Cc6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K04 compound treatment 308600.0 -112000.0 -0.95 280040.0 -119000.0 -1.01 -1.3866 -0.9995 3614558 BCB03_000825 ONC(=O)/C=C/c1ccc(OCCc2ccccn2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K05 compound treatment 212640.0 -208000.0 -1.77 111430.0 -288000.0 -2.44 -2.9752 -0.9874 3614560 BCB03_000826 COC(=O)C1(CCCC1)N2CC3=CCCC=C[C@H]3[C@@H]2[C@@H](O)Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K06 compound treatment 157860.0 -262000.0 -2.23 171260.0 -228000.0 -1.93 -2.9458 -0.9974 3614562 BCB03_000827 ONC(=O)/C=C/c1ccc(OCCNCc2ccccc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K07 mock treatment 539240.0 119000.0 1.01 515140.0 116000.0 0.98 1.411 0.9999 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K08 mock treatment 501440.0 81200.0 0.69 459240.0 60000.0 0.51 0.8484 0.9888 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K09 compound treatment 465760.0 45500.0 0.39 350990.0 -48200.0 -0.41 -0.0156 -0.0277 3614565 BCB03_000828 C=C/C=C/[C@H]1[C@@H]2[C@H](Cc3ccccc3)OC(=O)C4(CCCC4)N2CC1=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K10 compound treatment 407430.0 -12900.0 -0.11 380920.0 -18300.0 -0.15 -0.1869 -0.9854 1065487 BCB03_000829 ONC(=O)CCCc1ccccc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K11 compound treatment 344200.0 -76100.0 -0.65 258680.0 -141000.0 -1.19 -1.3005 -0.9588 3614570 BCB03_000830 O=C1O[C@@H](Cc2ccccc2)[C@H]3[C@@H]4C=CCCC=C4CN3C51CCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K12 compound treatment 432240.0 12000.0 0.1 334900.0 -64300.0 -0.55 -0.3137 -0.5655 3614573 BCB03_000831 CCCC(CCC)C(=O)NO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K13 compound treatment 459240.0 39000.0 0.33 460500.0 61300.0 0.52 0.6021 0.9763 3614575 BCB03_000832 COC(=O)C1(CCCC1)N2CC3=C[C@@H]([C@@H](O)Cc4ccccc4)n5n([C@@H]3[C@H](O2)C6CC6)c(=O)n(C)c5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K14 compound treatment 471360.0 51100.0 0.43 466660.0 67500.0 0.57 0.7119 0.9908 3614578 BCB03_000833 Oc1ccc2ncnc(NCC=C)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K15 mock treatment 433730.0 13400.0 0.11 458440.0 59200.0 0.5 0.4362 0.8464 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K16 mock treatment 462240.0 42000.0 0.36 447680.0 48500.0 0.41 0.5432 0.9975 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K17 compound treatment 450430.0 30100.0 0.26 424290.0 25100.0 0.21 0.3319 0.9957 3614579 BCB03_000834 COC(=O)C1(CCCC1)N2CC3=C[C@@H](C4CC4)n5n([C@H]3[C@@H]2[C@@H](O)Cc6ccccc6)c(=O)n(C)c5=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K18 compound treatment 476480.0 56200.0 0.48 442840.0 43600.0 0.37 0.5998 0.992 3614582 BCB03_000835 CCCNc1ncnc2ccc(O)cc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K19 compound treatment 465400.0 45100.0 0.38 462280.0 63100.0 0.54 0.6498 0.9867 3614584 BCB03_000836 COC(=O)C1(CCCC1)N2C[C@](C)(OC)O[C@@H](Cc3ccccc3)[C@H]2/C=C/C4CC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K20 compound treatment 415170.0 -5120.0 -0.04 263580.0 -136000.0 -1.15 -0.8442 -0.7333 2065681 BCB03_000837 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K21 compound treatment 325890.0 -94400.0 -0.8 329390.0 -69800.0 -0.59 -0.9865 -0.9888 3614590 BCB03_000838 COC(=O)C1(CCCC1)N2CC(=C)[C@@H](/C=C/C=C)[C@@H]2[C@@H](O)Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K22 compound treatment 397330.0 -23000.0 -0.2 323200.0 -76000.0 -0.64 -0.5939 -0.8818 3216001 BCB03_000839 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K23 mock treatment 481360.0 61100.0 0.52 384710.0 -14500.0 -0.12 0.2805 0.5254 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 K24 mock treatment 398370.0 -21900.0 -0.19 404820.0 5630.0 0.05 -0.0981 -0.5096 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L01 compound treatment 270990.0 -149000.0 -1.27 434110.0 34900.0 0.3 -0.6887 -0.528 3614594 BCB03_000840 Nc1ccccc1c2cn(CC(=O)Nc3nccs3)nn2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L02 mock treatment 392750.0 -27500.0 -0.23 360820.0 -38400.0 -0.33 -0.3958 -0.987 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L03 compound treatment 449320.0 29000.0 0.25 399280.0 87.9 0.0 0.1752 0.7092 3614596 BCB03_000841 Nc1ccccc1c2cn(CC(=O)Nc3ccon3)nn2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L04 mock treatment 370970.0 -49300.0 -0.42 393000.0 -6190.0 -0.05 -0.3338 -0.7895 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L05 compound treatment 443400.0 23100.0 0.2 413620.0 14400.0 0.12 0.2256 0.974 3556414 BCB03_000842 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L06 mock treatment 501400.0 81100.0 0.69 299650.0 -99500.0 -0.84 -0.1091 -0.1001 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L07 mock treatment 481570.0 61300.0 0.52 433220.0 34000.0 0.29 0.5728 0.9611 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L08 mock treatment 453160.0 32900.0 0.28 490910.0 91700.0 0.78 0.7479 0.9046 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L09 compound treatment 388450.0 -31800.0 -0.27 352080.0 -47100.0 -0.4 -0.4741 -0.982 3556416 BCB03_000843 COC(=O)c1c(C(=O)OC)c2oc1CC[C@@H](CO)NC(=O)N[C@H](Cc3ccccc3)c4cn(C[C@H](Cc5ccccc5)NC2=O)nn4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L10 mock treatment 491740.0 71500.0 0.61 458180.0 59000.0 0.5 0.7836 0.9953 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L11 compound treatment 464500.0 44200.0 0.38 500930.0 102000.0 0.86 0.8762 0.9307 3614599 BCB03_000844 CN1C(=O)[C@@H]2[C@H](C1=O)[C@]34COC[C@@H](N4C(=O)[C@@]2(O3)C(=O)C)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L12 mock treatment 395490.0 -24800.0 -0.21 386300.0 -12900.0 -0.11 -0.2265 -0.9532 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L13 compound treatment 488020.0 67700.0 0.58 450650.0 51500.0 0.44 0.7161 0.9906 3614605 BCB03_000845 Cc1ccc(cc1)S(=O)(=O)N2CCC[C@H]2Cn3cc(nn3)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L14 mock treatment 474320.0 54000.0 0.46 476500.0 77300.0 0.66 0.7887 0.9849 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L15 mock treatment 480970.0 60700.0 0.52 446290.0 47100.0 0.4 0.6475 0.992 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L16 mock treatment 486020.0 65700.0 0.56 474080.0 74900.0 0.64 0.8446 0.998 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L17 compound treatment 440000.0 19700.0 0.17 427560.0 28400.0 0.24 0.2887 0.9844 3614607 BCB03_000846 CN1C(=O)[C@H]2[C@@H](C1=O)[C@@]34COC[C@@H](N4C(=O)[C@]2(O3)C(=O)C)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L18 mock treatment 476360.0 56100.0 0.48 422570.0 23400.0 0.2 0.4775 0.9244 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L19 compound treatment 504980.0 84700.0 0.72 417440.0 18200.0 0.15 0.6189 0.8399 3614609 BCB03_000847 CC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L20 mock treatment 450090.0 29800.0 0.25 311920.0 -87300.0 -0.74 -0.3442 -0.4399 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L21 compound treatment 433120.0 12800.0 0.11 398080.0 -1110.0 -0.01 0.0705 0.6436 3614611 BCB03_000848 CC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L22 mock treatment 455760.0 35500.0 0.3 438850.0 39700.0 0.34 0.4513 0.9985 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L23 mock treatment 464850.0 44600.0 0.38 397170.0 -2020.0 -0.02 0.2559 0.6744 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 L24 mock treatment 446010.0 25700.0 0.22 442880.0 43700.0 0.37 0.4168 0.9684 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M01 compound treatment 4130.0 -416000.0 -3.54 3040.0 -396000.0 -3.36 -4.8796 -0.9997 3614612 BCB03_000849 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC4=CC(=O)[C@H](C5CC5)[C@H]4[C@@H]3[C@@H](O)Cc6ccccc6)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M02 compound treatment 431840.0 11600.0 0.1 283760.0 -115000.0 -0.98 -0.6229 -0.633 3215997 BCB03_000850 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)N(Cc6ccccc6)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M03 compound treatment 444410.0 24100.0 0.21 422190.0 23000.0 0.2 0.2831 0.9997 3614614 BCB03_000851 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3CC(=C)[C@@H](/C=C/C=C)[C@@H]3[C@@H](O)Cc4ccccc4)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M04 compound treatment 463690.0 43400.0 0.37 414830.0 15600.0 0.13 0.3549 0.9045 3216003 BCB03_000852 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M05 compound treatment 17180.0 -403000.0 -3.43 17920.0 -381000.0 -3.23 -4.7119 -0.9996 3614616 BCB03_000853 O=C1C=C2CN3[C@H]([C@@H]2[C@H]1C4CC4)[C@H](Cc5ccccc5)OC(=O)C63CCCC6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M06 compound treatment 380320.0 -40000.0 -0.34 375140.0 -24100.0 -0.2 -0.3847 -0.9702 3215999 BCB03_000854 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)N(C)C3=O)c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M07 compound treatment 482350.0 62100.0 0.53 368960.0 -30200.0 -0.26 0.192 0.3271 3614620 BCB03_000855 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M08 compound treatment 444800.0 24500.0 0.21 421480.0 22300.0 0.19 0.2811 0.9988 3215995 BCB03_000856 CN1C(=O)[C@@H]2CC(=C3[C@H](OB(O)C[C@@H]3[C@@H]2C1=O)c4ccccc4)COc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M09 mock treatment 434030.0 13700.0 0.12 419010.0 19800.0 0.17 0.2015 0.9842 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M10 mock treatment 469760.0 49500.0 0.42 457280.0 58100.0 0.49 0.646 0.9969 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M11 compound treatment 454410.0 34100.0 0.29 298730.0 -100000.0 -0.85 -0.3973 -0.4413 3614624 BCB03_000857 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@@H](/C=C/C3CC3)[C@H](O)Cc4ccccc4)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M12 compound treatment 474130.0 53800.0 0.46 264550.0 -135000.0 -1.14 -0.4837 -0.3931 3215892 BCB03_000858 CC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M13 mock treatment 412420.0 -7870.0 -0.07 450880.0 51700.0 0.44 0.2627 0.5923 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M14 mock treatment 502360.0 82100.0 0.7 497520.0 98300.0 0.83 1.0835 0.9961 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M15 compound treatment 383170.0 -37100.0 -0.32 248900.0 -150000.0 -1.27 -1.1248 -0.8564 3614627 BCB03_000859 O[C@@H](Cc1ccccc1)[C@H]2O[C@@H](Cc3ccccc3)[C@@H](/C=C/C4CC4)N2CC#C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M16 compound treatment 429280.0 8990.0 0.08 301920.0 -97300.0 -0.83 -0.5294 -0.6388 3215890 BCB03_000860 COCC1=C2[C@H](OB(O)C[C@@H]2n3n(C1)c(=O)n(c4ccccc4)c3=O)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M17 compound treatment 477760.0 57500.0 0.49 392070.0 -7120.0 -0.06 0.303 0.6151 3562141 BCB03_000861 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N(CC#C)[C@H](/C=C/C3CC3)[C@@H](O)Cc4ccccc4)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M18 compound treatment 366240.0 -54000.0 -0.46 357460.0 -41700.0 -0.35 -0.5754 -0.9917 3215888 BCB03_000862 OB1C[C@H]2C(=C(COc3ccccc3)Cn4n2c(=O)n(c5ccccc5)c4=O)[C@H](O1)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M19 compound treatment 449790.0 29500.0 0.25 353440.0 -45800.0 -0.39 -0.097 -0.2098 3614632 BCB03_000863 O=C1O[C@H](C2CCCCC2)[C@H](/C=C/C3CC3)N(CC#C)C1Cc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M20 compound treatment 422880.0 2590.0 0.02 295370.0 -104000.0 -0.88 -0.6071 -0.6892 3215943 BCB03_000864 CC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M21 compound treatment 398520.0 -21800.0 -0.19 327460.0 -71700.0 -0.61 -0.5612 -0.8823 3614636 BCB03_000865 O=C1O[C@@H]([C@@H]2[C@H]3C=CCCC=C3CN2C1Cc4ccccc4)C5CCCCC5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M22 compound treatment 332280.0 -88000.0 -0.75 264010.0 -135000.0 -1.15 -1.3403 -0.9787 3215941 BCB03_000866 COCC1=C2[C@H](OB(O)C[C@@H]2[C@H]3[C@@H](C1)C(=O)c4ccccc4C3=O)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M23 compound treatment 428360.0 8070.0 0.07 325120.0 -74100.0 -0.63 -0.3957 -0.6261 3614641 BCB03_000867 COC(=O)[C@@H]1N2[C@H](SC1(C)C)[C@H](N3[C@H](/C=C/C4CC4)[C@H](Cc5ccccc5)OC3=O)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 M24 compound treatment 379040.0 -41200.0 -0.35 266020.0 -133000.0 -1.13 -1.0469 -0.885 3215939 BCB03_000868 OB1C[C@@H]2[C@H]3[C@@H](CC(=C2[C@H](O1)c4ccccc4)COc5ccccc5)C(=O)c6ccccc6C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N01 compound treatment 461600.0 41300.0 0.35 321090.0 -78100.0 -0.66 -0.22 -0.2933 3614646 BCB03_000869 C=CCOC(=O)[C@@]1(O[C@@]23COC[C@@H](N3C1=O)c4ccccc4)[C@H]5[C@@H]2C(=O)N(C5=O)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N02 mock treatment 459360.0 39100.0 0.33 475950.0 76800.0 0.65 0.6955 0.9513 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N03 compound treatment 474190.0 53900.0 0.46 422500.0 23300.0 0.2 0.4641 0.9293 3614650 BCB03_000870 C=CCOC(=O)[C@]1(O[C@]23COC[C@@H](N3C1=O)c4ccccc4)[C@@H]5[C@H]2C(=O)N(C5=O)c6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N04 mock treatment 506080.0 85800.0 0.73 400160.0 968.0 0.01 0.5219 0.715 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N05 compound treatment 403650.0 -16600.0 -0.14 300370.0 -98800.0 -0.84 -0.6928 -0.815 3614652 BCB03_000871 O=C(NCc1ccccc1)[C@@]2(O[C@@]34COC[C@@H](N4C2=O)c5ccccc5)[C@H]6[C@@H]3C(=O)N(C6=O)c7ccccc7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N06 mock treatment 432250.0 12000.0 0.1 483010.0 83800.0 0.71 0.5747 0.8002 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N07 compound treatment 444480.0 24200.0 0.21 452740.0 53500.0 0.45 0.4667 0.9359 3614656 BCB03_000872 O=C(NCCc1c[nH]c2ccccc12)[C@@]3(O[C@@]45COC[C@@H](N5C3=O)c6ccccc6)[C@H]7[C@@H]4C(=O)N(C7=O)c8ccccc8 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N08 mock treatment 460160.0 39900.0 0.34 474400.0 75200.0 0.64 0.691 0.9563 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N09 mock treatment 509660.0 89400.0 0.76 447530.0 48300.0 0.41 0.8276 0.958 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N10 mock treatment 482690.0 62400.0 0.53 458450.0 59300.0 0.5 0.7308 0.9996 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N11 compound treatment 483570.0 63300.0 0.54 485280.0 86100.0 0.73 0.8971 0.9888 3614660 BCB03_000873 COC(=O)c1c(COC[C@@H](NC(=O)N(C)Cc2ccccc2)c3ccccc3)oc(C(=O)OCC=C)c1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N12 mock treatment 498430.0 78100.0 0.66 341940.0 -57300.0 -0.49 0.1267 0.1539 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N13 mock treatment 523540.0 103000.0 0.88 479470.0 80300.0 0.68 1.1026 0.9921 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N14 mock treatment 464160.0 43900.0 0.37 428200.0 29000.0 0.25 0.4379 0.9796 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N15 compound treatment 432960.0 12700.0 0.11 464210.0 65000.0 0.55 0.4662 0.8296 3614664 BCB03_000874 COc1cc(/C=C(\C#N)/C(=O)Nc2nnc(s2)C(F)(F)F)ccc1OCc3ccc(cc3C(F)(F)F)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N16 mock treatment 397340.0 -22900.0 -0.2 458080.0 58900.0 0.5 0.2152 0.4012 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N17 compound treatment 459700.0 39400.0 0.34 462910.0 63700.0 0.54 0.6193 0.9736 1917883 BCB03_000875 O/N=C/1\C2(CCCCC2)C(=O)N(O)C31CCCC=C3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N18 mock treatment 360360.0 -59900.0 -0.51 461500.0 62300.0 0.53 0.0132 0.018 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N19 compound treatment 393540.0 -26700.0 -0.23 354980.0 -44200.0 -0.38 -0.4261 -0.9713 3614668 BCB03_000876 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)c9cc%10ccccc%10s9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N20 mock treatment 433680.0 13400.0 0.11 427290.0 28100.0 0.24 0.2491 0.9429 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N21 compound treatment 300050.0 -120000.0 -1.02 380480.0 -18700.0 -0.16 -0.8355 -0.8072 3614669 BCB03_000877 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)n7c(=O)[nH]c8ccccc78)C(=C5)C(=O)C9CCCCC9 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N22 mock treatment 408610.0 -11700.0 -0.1 385830.0 -13400.0 -0.11 -0.1504 -0.9978 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N23 compound treatment 401760.0 -18500.0 -0.16 367260.0 -31900.0 -0.27 -0.303 -0.9668 3614671 BCB03_000878 C[C@@]12CCC3[C@@]4(C)CC[C@H](O)CC54C=CC3(C2CC[C@@]1(O)CN6CCC(CC6)C(=O)N)C(=C5)C(=O)c7ccc(F)c(F)c7 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 N24 mock treatment 456770.0 36500.0 0.31 402410.0 3220.0 0.03 0.2388 0.7663 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O01 compound treatment 204740.0 -216000.0 -1.83 330980.0 -68200.0 -0.58 -1.7058 -0.8871 3614673 BCB03_000879 COC(=O)[C@H](Cc1ccccc1)N2[C@@H](/C=C/C3CC3)[C@@H](Cc4ccccc4)OC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O02 compound treatment 476740.0 56500.0 0.48 412280.0 13100.0 0.11 0.4181 0.8482 2065712 BCB03_000880 CC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O03 compound treatment 387780.0 -32500.0 -0.28 435600.0 36400.0 0.31 0.0228 0.0551 3614677 BCB03_000881 COC(=O)C1(CCCC1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O04 compound treatment 454960.0 34700.0 0.29 439210.0 40000.0 0.34 0.4486 0.9976 3215981 BCB03_000882 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(Cc4ccccc4)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O05 compound treatment 287140.0 -133000.0 -1.13 341090.0 -58100.0 -0.49 -1.1495 -0.9305 3614680 BCB03_000883 COC(=O)[C@H](Cc1ccccc1)N2[C@H](/C=C/C3CC3)[C@H](Cc4ccccc4)OC2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O06 compound treatment 419130.0 -1160.0 -0.01 454590.0 55400.0 0.47 0.3253 0.6921 3215977 BCB03_000884 OC[C@@H]1[C@H]2[C@@H](CC(=C1[C@H](O)c3ccccc3)COc4ccccc4)C(=O)N(Cc5ccccc5)C2=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O07 compound treatment 456480.0 36200.0 0.31 430740.0 31500.0 0.27 0.4069 0.9976 3563099 BCB03_000885 COC(=O)C1=CN(C)C(C)c2ccccc2C=C1C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O08 compound treatment 417090.0 -3200.0 -0.03 371290.0 -27900.0 -0.24 -0.1866 -0.7832 2065737 BCB03_000886 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O09 compound treatment 418690.0 -1600.0 -0.01 455220.0 56000.0 0.48 0.3265 0.6866 3563100 BCB03_000887 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@H](C)c3ccccc23 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O10 compound treatment 399410.0 -20900.0 -0.18 392450.0 -6740.0 -0.06 -0.166 -0.8898 3215979 BCB03_000888 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)[C@H]3[C@@H](C1)C(=O)N(C)C3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O11 mock treatment 431850.0 11600.0 0.1 388450.0 -10700.0 -0.09 0.0051 0.0382 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O12 mock treatment 389010.0 -31300.0 -0.27 410190.0 11000.0 0.09 -0.1222 -0.4333 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O13 compound treatment 453220.0 32900.0 0.28 432580.0 33400.0 0.28 0.3984 1.0 3563102 BCB03_000889 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C)c3ccccc23 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O14 compound treatment 343520.0 -76800.0 -0.65 280960.0 -118000.0 -1.0 -1.171 -0.9784 3215975 BCB03_000890 CN1C(=O)[C@@H]2CC(=C([C@H](O)c3ccccc3)[C@H](CO)[C@@H]2C1=O)COc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O15 compound treatment 449390.0 29100.0 0.25 363840.0 -35400.0 -0.3 -0.037 -0.0951 3563103 BCB03_000891 CC1N(C)/C(=N\P(=O)(Oc2ccccc2)Oc3ccccc3)/Cc4ccccc14 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O16 compound treatment 446500.0 26200.0 0.22 386330.0 -12900.0 -0.11 0.0805 0.3244 3215878 BCB03_000892 CC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O17 compound treatment 403700.0 -16600.0 -0.14 438780.0 39600.0 0.34 0.1377 0.378 3563106 BCB03_000893 CN/1C(C=C)c2ccccc2C\C1=N\P(=O)(Oc3ccccc3)Oc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O18 compound treatment 396650.0 -23600.0 -0.2 421440.0 22200.0 0.19 -0.0087 -0.0317 3215876 BCB03_000894 COCC1=C([C@H](O)c2ccccc2)[C@H](CO)n3n(C1)c(=O)n(c4ccccc4)c3=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O19 compound treatment 418330.0 -1960.0 -0.02 414510.0 15300.0 0.13 0.0801 0.6115 3563109 BCB03_000895 CCOC(=O)C1=C2[C@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O20 compound treatment 354280.0 -66000.0 -0.56 396960.0 -2230.0 -0.02 -0.4105 -0.7305 3215874 BCB03_000896 OC[C@H]1C(=C(COc2ccccc2)Cn3n1c(=O)n(c4ccccc4)c3=O)[C@H](O)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O21 compound treatment 383910.0 -36400.0 -0.31 439270.0 40100.0 0.34 0.0216 0.0469 3563111 BCB03_000897 CCOC(=O)C1=C2[C@@H](ON1)N(C)[C@@H](C3CC3)c4ccccc24 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O22 compound treatment 352530.0 -67800.0 -0.58 311540.0 -87700.0 -0.74 -0.9334 -0.9921 3216007 BCB03_000898 C[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O23 compound treatment 434450.0 14200.0 0.12 404800.0 5610.0 0.05 0.1188 0.9174 3563112 BCB03_000899 CN/1C(C2CC2)c3ccccc3C\C1=N\P(=O)(Oc4ccccc4)Oc5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 O24 compound treatment 359850.0 -60400.0 -0.51 359790.0 -39400.0 -0.33 -0.5999 -0.9782 3216011 BCB03_000900 COC[C@]1(C[C@@H]2[C@H]([C@H]/3CO1)C(=O)N(Cc4ccccc4)C2=O)\C3=C\c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P01 compound treatment 279270.0 -141000.0 -1.2 225070.0 -174000.0 -1.48 -1.8927 -0.9947 3614688 BCB03_000901 COc1ccc(cc1OC2CCCC2)C3=NOC(C3)C(=O)NO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P02 mock treatment 346600.0 -73700.0 -0.63 370810.0 -28400.0 -0.24 -0.6135 -0.9136 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P03 compound treatment 298720.0 -122000.0 -1.03 273610.0 -126000.0 -1.07 -1.4846 -0.9999 3614690 BCB03_000902 CC(=O)c1ccc(NC(=S)Nc2ccc(Nc3ccccc3)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P04 mock treatment 344820.0 -75500.0 -0.64 374310.0 -24900.0 -0.21 -0.6032 -0.8926 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P05 compound treatment 341480.0 -78800.0 -0.67 385000.0 -14200.0 -0.12 -0.5592 -0.8209 3614693 BCB03_000903 COC(=O)c1cn(CC(=O)O)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P06 mock treatment 354620.0 -65700.0 -0.56 350990.0 -48200.0 -0.41 -0.6842 -0.9882 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P07 compound treatment 292580.0 -128000.0 -1.09 263150.0 -136000.0 -1.15 -1.5842 -0.9995 3614695 BCB03_000904 COC(=O)c1cn(CCC(=O)O)nn1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P08 mock treatment 292450.0 -128000.0 -1.09 303210.0 -96000.0 -0.81 -1.3447 -0.9898 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P09 compound treatment 273880.0 -146000.0 -1.25 250470.0 -149000.0 -1.26 -1.7728 -1.0 1366116 BCB03_000905 Brc1ccc2ncnc(NCC=C)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P10 mock treatment 294460.0 -126000.0 -1.07 319540.0 -79700.0 -0.68 -1.2347 -0.9754 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P11 mock treatment 326030.0 -94300.0 -0.8 275320.0 -124000.0 -1.05 -1.31 -0.9911 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P12 mock treatment 238530.0 -182000.0 -1.55 349600.0 -49600.0 -0.42 -1.3908 -0.8679 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P13 compound treatment 192400.0 -228000.0 -1.94 166680.0 -233000.0 -1.97 -2.7655 -1.0 1263689 BCB03_000906 Brc1ccc2ncnc(NCc3ccccc3)c2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P14 mock treatment 281280.0 -139000.0 -1.18 330850.0 -68300.0 -0.58 -1.2461 -0.9462 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P15 compound treatment 235970.0 -184000.0 -1.57 255370.0 -144000.0 -1.22 -1.9714 -0.9923 1385097 BCB03_000907 CCCNc1ncnc2ccc(Br)cc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P16 mock treatment 312180.0 -108000.0 -0.92 328320.0 -70900.0 -0.6 -1.0754 -0.9788 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P17 compound treatment 186640.0 -234000.0 -1.99 196830.0 -202000.0 -1.72 -2.6193 -0.9973 3614697 BCB03_000908 CC(C)(C)OC(=O)NCCOCCOCCNc1ncnc2ccc(Br)cc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P18 mock treatment 333920.0 -86400.0 -0.73 303360.0 -95800.0 -0.81 -1.0944 -0.9987 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P19 compound treatment 275360.0 -145000.0 -1.23 279730.0 -119000.0 -1.01 -1.5884 -0.9953 3614698 BCB03_000909 CCOc1ncnc2ccc(Br)cc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P20 mock treatment 270280.0 -150000.0 -1.28 327430.0 -71800.0 -0.61 -1.3328 -0.9427 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P21 compound treatment 294810.0 -125000.0 -1.07 237140.0 -162000.0 -1.37 -1.7268 -0.9922 1985613 BCB03_000910 C=CCNc1ncnc2ccccc12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P22 mock treatment 288800.0 -131000.0 -1.12 335930.0 -63300.0 -0.54 -1.1704 -0.9434 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P23 compound treatment 257630.0 -163000.0 -1.38 269280.0 -130000.0 -1.1 -1.7577 -0.9936 1412880 BCB03_000911 C(Nc1ncnc2ccccc12)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2283 P24 mock treatment 256520.0 -164000.0 -1.39 211890.0 -187000.0 -1.59 -2.1086 -0.9979 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A01 mock treatment 436740.0 16300.0 0.14 455050.0 30600.0 0.26 0.2813 0.9567 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A02 compound treatment 414240.0 -6230.0 -0.05 402140.0 -22300.0 -0.19 -0.1714 -0.8716 3555546 CMLD3_000001 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A03 mock treatment 439360.0 18900.0 0.16 452480.0 28000.0 0.24 0.2816 0.9818 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A04 compound treatment 276320.0 -144000.0 -1.23 404960.0 -19500.0 -0.17 -0.9842 -0.7953 3555566 CMLD3_000002 COc1ccc2C(=O)[C@@H](OC(=O)NCCOc3ccccc3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A05 compound treatment 460660.0 40200.0 0.34 467610.0 43100.0 0.37 0.5005 0.9994 3555570 CMLD3_000003 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A06 compound treatment 233120.0 -187000.0 -1.59 276040.0 -148000.0 -1.26 -2.0173 -0.9932 3555574 CMLD3_000004 COc1ccc2O[C@H]([C@H](O)C(=O)c2c1)c3ccc(OC)c(Br)c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A07 mock treatment 201070.0 -219000.0 -1.87 376320.0 -48100.0 -0.41 -1.6086 -0.8419 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A08 compound treatment 380170.0 -40300.0 -0.34 323890.0 -101000.0 -0.85 -0.8457 -0.9198 3555579 CMLD3_000005 COc1ccc2O[C@H]([C@H](OC(=O)NCCOc3ccccc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A09 compound treatment 330470.0 -90000.0 -0.77 415090.0 -9380.0 -0.08 -0.5977 -0.7764 3555584 CMLD3_000006 Brc1ccc2O[C@H]([C@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc6OCOc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A10 compound treatment 477140.0 56700.0 0.48 411200.0 -13300.0 -0.11 0.2613 0.5278 3555589 CMLD3_000007 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@@H]1Cc2cc(Br)ccc2O[C@H]1c3cccc(OC)c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A11 mock treatment 379620.0 -40900.0 -0.35 252020.0 -172000.0 -1.46 -1.2801 -0.8514 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A12 compound treatment 356530.0 -63900.0 -0.54 381410.0 -43100.0 -0.37 -0.6429 -0.9812 3555594 CMLD3_000008 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A13 mock treatment 456590.0 36100.0 0.31 477660.0 53200.0 0.45 0.5363 0.9825 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A14 mock treatment 454400.0 33900.0 0.29 279210.0 -145000.0 -1.23 -0.6672 -0.5272 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A15 compound treatment 298610.0 -122000.0 -1.04 318480.0 -106000.0 -0.9 -1.3688 -0.9975 3555598 CMLD3_000009 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)c2cc(C)cc(C)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A16 compound treatment 441840.0 21400.0 0.18 389550.0 -34900.0 -0.3 -0.0809 -0.2328 3555600 CMLD3_000010 Cc1cc(C)cc(/C=C/[C@H]2OC[C@@H](O)[C@H]2Oc3ccc(cc3)C4CCCC4)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A17 compound treatment 117080.0 -303000.0 -2.58 142330.0 -282000.0 -2.39 -3.5174 -0.9993 3555605 CMLD3_000011 COc1ccc(C#C[C@H]2O[C@H](CO)[C@@H](Oc3cc(C)cc(C)c3)C=C2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A18 compound treatment 11230.0 -409000.0 -3.48 10720.0 -414000.0 -3.51 -4.9436 -1.0 3555609 CMLD3_000012 CC(C)(C)OC(=O)C1=NOC2(C1)C=CC(=O)C=C2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A19 compound treatment 403330.0 -17100.0 -0.15 368800.0 -55700.0 -0.47 -0.437 -0.8843 3555611 CMLD3_000013 COC(=O)N[C@@H](c1ccccc1)[C@@]2(CCCC2=O)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A20 compound treatment 389040.0 -31400.0 -0.27 267090.0 -157000.0 -1.33 -1.1331 -0.8322 3555615 CMLD3_000014 CCCCCCCC#Cc1ccccc1C(NC(=O)OC)C(C(=O)OC)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A21 compound treatment 404990.0 -15500.0 -0.13 373440.0 -51000.0 -0.43 -0.3992 -0.8823 3555617 CMLD3_000015 CC(C)(C)OC1C2C3C2C4C1C3CC=CC4(O)CC=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A22 compound treatment 423950.0 3480.0 0.03 395490.0 -29000.0 -0.25 -0.1529 -0.6176 3555619 CMLD3_000016 COCn1c2ccccc2c3nnc(nc13)C(=O)O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A23 compound treatment 260270.0 -160000.0 -1.36 267690.0 -157000.0 -1.33 -1.9041 -0.9999 3555621 CMLD3_000017 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2cccs2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 A24 compound treatment 424020.0 3550.0 0.03 368640.0 -55800.0 -0.47 -0.3135 -0.6607 3555626 CMLD3_000018 CC(=CCC/C(=C/C=C/C1=CC2(C)CC1(C)C(CC2=O)\C=C(/C)\CCC=C(C)C)/C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B01 compound treatment 440960.0 20500.0 0.17 488530.0 64100.0 0.54 0.5075 0.8893 3555630 CMLD3_000019 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B02 compound treatment 204740.0 -216000.0 -1.84 246250.0 -178000.0 -1.51 -2.3667 -0.9954 3555635 CMLD3_000020 COc1ccc2C(=O)[C@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B03 compound treatment 446840.0 26400.0 0.22 452640.0 28200.0 0.24 0.3276 0.9995 3555639 CMLD3_000021 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B04 compound treatment 443110.0 22600.0 0.19 448430.0 24000.0 0.2 0.2799 0.9996 3555643 CMLD3_000022 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@@H](Oc2c1)c5ccc6OCOc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B05 compound treatment 417880.0 -2590.0 -0.02 400640.0 -23800.0 -0.2 -0.1585 -0.7796 3555647 CMLD3_000023 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3ccc4OCOc4c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B06 compound treatment 354420.0 -66100.0 -0.56 411760.0 -12700.0 -0.11 -0.4736 -0.8277 3555651 CMLD3_000024 COc1ccc2C(=O)[C@H](O)[C@H](Oc2c1)c3ccc4OCOc4c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B07 compound treatment 463680.0 43200.0 0.37 400020.0 -24400.0 -0.21 0.1133 0.2684 3555653 CMLD3_000025 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B08 compound treatment 464400.0 43900.0 0.37 437490.0 13000.0 0.11 0.3424 0.8786 3555657 CMLD3_000026 COc1ccc2C(=O)[C@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@H](Oc2c1)c5ccc6OCOc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B09 compound treatment 281300.0 -139000.0 -1.18 285460.0 -139000.0 -1.18 -1.671 -1.0 3555659 CMLD3_000027 COc1ccc2C(=O)[C@H](OC(=O)N[C@H](C)C3CCCCC3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B10 compound treatment 449440.0 29000.0 0.25 486490.0 62000.0 0.53 0.5463 0.9403 3555663 CMLD3_000028 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B11 compound treatment 461040.0 40600.0 0.35 453830.0 29400.0 0.25 0.4202 0.9872 3555666 CMLD3_000029 COc1ccc2O[C@H]([C@H](OC(=O)Nc3ccc(C)c(Br)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B12 compound treatment 388390.0 -32100.0 -0.27 309130.0 -115000.0 -0.98 -0.8848 -0.8711 3555670 CMLD3_000030 COc1ccc2C(=O)[C@H](OC(=O)NCCOc3ccccc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B13 mock treatment 438240.0 17800.0 0.15 338050.0 -86400.0 -0.73 -0.4115 -0.5497 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B14 mock treatment 458190.0 37700.0 0.32 454910.0 30400.0 0.26 0.4095 0.9942 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B15 compound treatment 360860.0 -59600.0 -0.51 314160.0 -110000.0 -0.94 -1.0202 -0.9586 3555672 CMLD3_000031 CC(=O)c1ccc(cc1)[C@H]2O[C@H](CO)[C@@H](Oc3ccc(cc3)c4ccccc4)C=C2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B16 compound treatment 349850.0 -70600.0 -0.6 326210.0 -98300.0 -0.83 -1.0142 -0.9871 3555676 CMLD3_000032 CC(C)(C)c1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccccc3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B17 compound treatment 269230.0 -151000.0 -1.29 213600.0 -211000.0 -1.79 -2.1746 -0.9869 3555680 CMLD3_000033 CC(=O)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(Br)cc3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B18 compound treatment 348890.0 -71600.0 -0.61 335580.0 -88900.0 -0.75 -0.9638 -0.9944 3555686 CMLD3_000034 COc1ccc(/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4ccc(OC)cc4)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B19 compound treatment 463640.0 43200.0 0.37 365530.0 -58900.0 -0.5 -0.0938 -0.1513 3555689 CMLD3_000035 COC(=O)N[C@H](CC(=O)C)c1ccc2OCOc2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B20 mock treatment 413020.0 -7450.0 -0.06 434600.0 10100.0 0.09 0.0159 0.1493 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B21 compound treatment 360040.0 -60400.0 -0.51 377600.0 -46900.0 -0.4 -0.6447 -0.9919 3555694 CMLD3_000036 COCO[C@@H]1[C@@H](C)C(=O)N2[C@@H]1[C@@H](Oc3ccc(OC)cc23)/C=C/C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B22 compound treatment 417960.0 -2510.0 -0.02 412390.0 -12100.0 -0.1 -0.0876 -0.8366 3555700 CMLD3_000037 C[C@@H]1C=CCCO[C@H]1c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B23 compound treatment 288000.0 -132000.0 -1.13 372050.0 -52400.0 -0.44 -1.1113 -0.9173 3555703 CMLD3_000038 CCCCCCCC#Cc1ccccc1/C=N/S(=O)c2ccc(C)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 B24 compound treatment 357840.0 -62600.0 -0.53 377760.0 -46700.0 -0.4 -0.6569 -0.9894 3555707 CMLD3_000039 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)c3ccccn3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C01 compound treatment 368020.0 -52500.0 -0.45 380000.0 -44500.0 -0.38 -0.5823 -0.9965 3555711 CMLD3_000040 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3[C@H](O)[C@H]2O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C02 compound treatment 394650.0 -25800.0 -0.22 421360.0 -3110.0 -0.03 -0.174 -0.7863 3555810 CMLD3_000041 COc1ccc2C(=O)[C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C03 compound treatment 419950.0 -523.0 0.0 446740.0 22300.0 0.19 0.1305 0.6903 3555814 CMLD3_000042 CCOC(=O)CNC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C04 compound treatment 286890.0 -134000.0 -1.14 412040.0 -12400.0 -0.11 -0.8781 -0.7694 3555817 CMLD3_000043 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2[C@H](Oc3ccc(OC)cc3C2=O)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C05 compound treatment 264040.0 -156000.0 -1.33 277830.0 -147000.0 -1.24 -1.8206 -0.9994 3555820 CMLD3_000044 COc1ccc2O[C@@H]([C@@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C06 compound treatment 406200.0 -14300.0 -0.12 339920.0 -84500.0 -0.72 -0.593 -0.8152 3555823 CMLD3_000045 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C07 compound treatment 448820.0 28300.0 0.24 387550.0 -36900.0 -0.31 -0.0509 -0.1288 3555825 CMLD3_000046 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3cccc(OC)c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C08 compound treatment 383840.0 -36600.0 -0.31 421060.0 -3410.0 -0.03 -0.2408 -0.7694 3555829 CMLD3_000047 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NC4CCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C09 compound treatment 420860.0 387.0 0.0 377840.0 -46600.0 -0.4 -0.2773 -0.7012 3555833 CMLD3_000048 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2[C@H](Oc3cc(OC)ccc3C2=O)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C10 compound treatment 350650.0 -69800.0 -0.59 417280.0 -7190.0 -0.06 -0.4631 -0.7756 3555837 CMLD3_000049 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C11 mock treatment 415870.0 -4600.0 -0.04 467140.0 42700.0 0.36 0.2283 0.627 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C12 mock treatment 422620.0 2150.0 0.02 418080.0 -6390.0 -0.05 -0.0254 -0.4441 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C13 compound treatment 425760.0 5290.0 0.04 385770.0 -38700.0 -0.33 -0.2003 -0.6046 3555841 CMLD3_000050 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]2Cc3cc(OC)ccc3O[C@H]2c4cccc(OC)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C14 compound treatment 420820.0 347.0 0.0 404060.0 -20400.0 -0.17 -0.1203 -0.6949 3555844 CMLD3_000051 CC(=O)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccc(Cl)cc3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C15 mock treatment 390430.0 -30000.0 -0.26 341480.0 -83000.0 -0.7 -0.6785 -0.906 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C16 mock treatment 416500.0 -3970.0 -0.03 424430.0 -36.7 0.0 -0.0241 -0.7136 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C17 compound treatment 246260.0 -174000.0 -1.48 211960.0 -213000.0 -1.8 -2.3226 -0.9953 3555848 CMLD3_000052 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2cccc(c2)N(C)C)C#Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C18 compound treatment 390980.0 -29500.0 -0.25 381820.0 -42600.0 -0.36 -0.4332 -0.984 3555853 CMLD3_000053 COC(=O)C1(CC2(CCC3C4C5C41)OCCO2)C3C5OCc6ccccc6 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C19 compound treatment 336560.0 -83900.0 -0.71 274560.0 -150000.0 -1.27 -1.404 -0.9627 3555855 CMLD3_000054 COc1cccc(/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4cccc(OC)c4)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C20 compound treatment 195070.0 -225000.0 -1.92 218600.0 -206000.0 -1.75 -2.5908 -0.9989 3555859 CMLD3_000055 COC(=O)[C@@H]1[C@H]([C@H]2C(=O)c3c(OC)cc(OC)cc3O[C@@]12c4ccc(OC)cc4)c5ccccc5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C21 compound treatment 35630.0 -385000.0 -3.27 33200.0 -391000.0 -3.32 -4.6619 -1.0 831758 CMLD3_000056 Oc1ccc(/C=C/C(=O)c2ccc(O)cc2O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C22 compound treatment 324550.0 -95900.0 -0.82 389160.0 -35300.0 -0.3 -0.7888 -0.9074 3555865 CMLD3_000057 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1cccc(C)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C23 compound treatment 387170.0 -33300.0 -0.28 377600.0 -46900.0 -0.4 -0.4815 -0.9862 3555869 CMLD3_000058 COC(=O)N[C@H](CC(=O)C)c1ccc(F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 C24 compound treatment 384160.0 -36300.0 -0.31 365000.0 -59500.0 -0.5 -0.5751 -0.9723 3555873 CMLD3_000059 CCCCCCCC1=CC2=CC(=O)C(C)(O)C(=O)C2=CN1CCCC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D01 compound treatment 430350.0 9880.0 0.08 447290.0 22800.0 0.19 0.1963 0.9302 3555876 CMLD3_000060 Cc1ccc(cc1)S(=O)(=O)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D02 compound treatment 394880.0 -25600.0 -0.22 298410.0 -126000.0 -1.07 -0.9101 -0.834 3555884 CMLD3_000061 COc1ccc2C(=O)[C@@H](OC(=O)NC3CCCC3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D03 compound treatment 404520.0 -16000.0 -0.14 466560.0 42100.0 0.36 0.1565 0.4097 3555888 CMLD3_000062 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D04 mock treatment 462840.0 42400.0 0.36 474530.0 50100.0 0.42 0.5552 0.9967 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D05 compound treatment 417870.0 -2600.0 -0.02 415860.0 -8610.0 -0.07 -0.0673 -0.8819 3555892 CMLD3_000063 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D06 compound treatment 418400.0 -2070.0 -0.02 370500.0 -54000.0 -0.46 -0.3362 -0.7338 3555896 CMLD3_000064 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D07 compound treatment 287400.0 -133000.0 -1.13 283940.0 -141000.0 -1.19 -1.6434 -0.9997 3555901 CMLD3_000065 COc1ccc2C(=O)[C@@H](OC(=O)NC3CCCC3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D08 mock treatment 359390.0 -61100.0 -0.52 475460.0 51000.0 0.43 -0.0616 -0.0911 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D09 compound treatment 435100.0 14600.0 0.12 311560.0 -113000.0 -0.96 -0.5892 -0.6101 3555905 CMLD3_000066 COc1cc(NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4)cc(OC)c1OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D10 compound treatment 319430.0 -101000.0 -0.86 327150.0 -97300.0 -0.83 -1.1916 -0.9998 3555908 CMLD3_000067 COc1ccc2O[C@@H]([C@@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D11 mock treatment 495080.0 74600.0 0.63 460360.0 35900.0 0.3 0.6641 0.9434 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D12 mock treatment 405190.0 -15300.0 -0.13 456640.0 32200.0 0.27 0.101 0.3343 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D13 mock treatment 418110.0 -2360.0 -0.02 392290.0 -32200.0 -0.27 -0.2072 -0.7571 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D14 compound treatment 357920.0 -62600.0 -0.53 371220.0 -53200.0 -0.45 -0.6957 -0.9967 3555912 CMLD3_000068 CN(C)c1cccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D15 mock treatment 401450.0 -19000.0 -0.16 453700.0 29200.0 0.25 0.0609 0.2057 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D16 mock treatment 451650.0 31200.0 0.27 461300.0 36800.0 0.31 0.4085 0.9967 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D17 compound treatment 390530.0 -29900.0 -0.25 472990.0 48500.0 0.41 0.1109 0.2292 3555916 CMLD3_000069 OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(C=O)cc2)C#Cc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D18 compound treatment 271220.0 -149000.0 -1.27 393690.0 -30800.0 -0.26 -1.0824 -0.835 3555921 CMLD3_000070 COc1ccccc1/C=C/C2=CC3(C)CC2(C)C(CC3=O)c4ccccc4OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D19 compound treatment 5490.0 -415000.0 -3.53 5510.0 -419000.0 -3.55 -5.0093 -1.0 3555925 CMLD3_000071 CCC/C=C/C1C(CO)C2(OCC(CC)(CC)CO2)[C@@H]3O[C@@H]3C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D20 compound treatment 438680.0 18200.0 0.15 375000.0 -49500.0 -0.42 -0.1872 -0.4185 3555929 CMLD3_000072 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)C(F)(F)F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D21 compound treatment 388980.0 -31500.0 -0.27 378630.0 -45800.0 -0.39 -0.4644 -0.9835 3555933 CMLD3_000073 COc1ccc(cc1)C(=O)CC(=O)c2c(O)cc(OC)cc2OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D22 compound treatment 419130.0 -1340.0 -0.01 400730.0 -23700.0 -0.2 -0.1505 -0.746 3555935 CMLD3_000074 COC(=O)N[C@@H](c1ccco1)[C@@]2(CCCC2=O)C(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D23 mock treatment 352660.0 -67800.0 -0.58 291400.0 -133000.0 -1.13 -1.2061 -0.9514 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 D24 compound treatment 392000.0 -28500.0 -0.24 444130.0 19700.0 0.17 -0.0533 -0.1814 3555939 CMLD3_000075 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1cccc(F)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E01 mock treatment 480840.0 60400.0 0.51 473780.0 49300.0 0.42 0.6589 0.9948 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E02 mock treatment 437780.0 17300.0 0.15 469880.0 45400.0 0.39 0.3765 0.913 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E03 mock treatment 466040.0 45600.0 0.39 463860.0 39400.0 0.33 0.5104 0.9973 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E04 compound treatment 346000.0 -74500.0 -0.63 431360.0 6890.0 0.06 -0.4066 -0.6391 3555943 CMLD3_000076 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E05 compound treatment 250520.0 -170000.0 -1.45 260960.0 -164000.0 -1.39 -2.0031 -0.9998 3555945 CMLD3_000077 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E06 compound treatment 302340.0 -118000.0 -1.0 319330.0 -105000.0 -0.89 -1.3413 -0.9982 3555948 CMLD3_000078 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E07 compound treatment 228850.0 -192000.0 -1.63 374330.0 -50100.0 -0.43 -1.4534 -0.8627 3555952 CMLD3_000079 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H](C)C3CCCCC3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E08 compound treatment 461400.0 40900.0 0.35 493720.0 69300.0 0.59 0.6616 0.9688 3555954 CMLD3_000080 COc1ccc2O[C@@H]([C@@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc(OC)c(Br)c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E09 mock treatment 452130.0 31700.0 0.27 421760.0 -2710.0 -0.02 0.1742 0.6445 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E10 mock treatment 468340.0 47900.0 0.41 486090.0 61600.0 0.52 0.6576 0.9924 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E11 compound treatment 285610.0 -135000.0 -1.15 252960.0 -172000.0 -1.45 -1.84 -0.9931 3555958 CMLD3_000081 Brc1ccc2O[C@H]([C@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E12 compound treatment 360880.0 -59600.0 -0.51 407520.0 -16900.0 -0.14 -0.4601 -0.8732 3555962 CMLD3_000082 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E13 compound treatment 371690.0 -48800.0 -0.42 486840.0 62400.0 0.53 0.0807 0.12 3555964 CMLD3_000083 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E14 compound treatment 428640.0 8170.0 0.07 403840.0 -20600.0 -0.17 -0.0746 -0.3962 3555968 CMLD3_000084 CCOC(=O)OC[C@H]1O[C@H](CCc2ccccc2)CC[C@@H]1Oc3ccc(OC)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E15 compound treatment 204880.0 -216000.0 -1.83 189520.0 -235000.0 -1.99 -2.7062 -0.9991 3555972 CMLD3_000085 CC(C)(C)c1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccccc3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E16 compound treatment 308670.0 -112000.0 -0.95 275080.0 -149000.0 -1.27 -1.5686 -0.99 3555975 CMLD3_000086 CC(C)(C)c1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccccc3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E17 mock treatment 417340.0 -3130.0 -0.03 389320.0 -35100.0 -0.3 -0.2297 -0.7673 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E18 mock treatment 434180.0 13700.0 0.12 283940.0 -141000.0 -1.19 -0.7604 -0.6349 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E19 compound treatment 402030.0 -18400.0 -0.16 393690.0 -30800.0 -0.26 -0.2955 -0.9703 3555978 CMLD3_000087 C[C@H](O)CCCCCCC/C=C/C=C/C(=O)N 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E20 compound treatment 433980.0 13500.0 0.11 429220.0 4750.0 0.04 0.1098 0.9013 3555982 CMLD3_000088 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cccc3c4ccccc4oc23)c5cccc6c7ccccc7oc56)C(O)(c8cccc9c%10ccccc%10oc89)c%11cccc%12c%13ccccc%13oc%11%12 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E21 mock treatment 415040.0 -5430.0 -0.05 309980.0 -114000.0 -0.97 -0.7194 -0.7399 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E22 compound treatment 426780.0 6310.0 0.05 401050.0 -23400.0 -0.2 -0.1025 -0.4982 3555987 CMLD3_000089 COC(=O)N[C@@H](c1cccc(C)c1)[C@@]2(CCCC2=O)C(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E23 compound treatment 385120.0 -35400.0 -0.3 406980.0 -17500.0 -0.15 -0.3176 -0.9469 3555990 CMLD3_000090 CC1(CC2(C)C(CC1=O)c3ccc(cc3)C(F)(F)F)C=C2/C=C/c4ccc(cc4)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 E24 mock treatment 385760.0 -34700.0 -0.3 439070.0 14600.0 0.12 -0.1212 -0.3785 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F01 mock treatment 411950.0 -8520.0 -0.07 466740.0 42300.0 0.36 0.2023 0.5529 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F02 mock treatment 446160.0 25700.0 0.22 413530.0 -10900.0 -0.09 0.0889 0.3746 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F03 compound treatment 399120.0 -21400.0 -0.18 410370.0 -14100.0 -0.12 -0.213 -0.9794 3555993 CMLD3_000091 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F04 compound treatment 323360.0 -97100.0 -0.83 361620.0 -62800.0 -0.53 -0.9612 -0.9775 3555995 CMLD3_000092 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F05 compound treatment 322090.0 -98400.0 -0.84 410160.0 -14300.0 -0.12 -0.6776 -0.8013 3555997 CMLD3_000093 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(C)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F06 mock treatment 398330.0 -22100.0 -0.19 437000.0 12500.0 0.11 -0.058 -0.2682 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F07 compound treatment 249280.0 -171000.0 -1.46 446960.0 22500.0 0.19 -0.8949 -0.6093 3555999 CMLD3_000094 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3cc(OC)ccc3C2=O)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F08 compound treatment 449850.0 29400.0 0.25 410660.0 -13800.0 -0.12 0.0939 0.3402 3556000 CMLD3_000095 COc1ccc2O[C@@H]([C@@H](OC(=O)N[C@H]3CCCc4ccccc34)C(=O)c2c1)c5ccc(OC)c(Br)c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F09 mock treatment 509380.0 88900.0 0.76 496320.0 71900.0 0.61 0.9658 0.9943 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F10 mock treatment 338940.0 -81500.0 -0.69 348640.0 -75800.0 -0.64 -0.9453 -0.9993 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F11 mock treatment 486480.0 66000.0 0.56 291490.0 -133000.0 -1.13 -0.4005 -0.3179 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F12 compound treatment 274800.0 -146000.0 -1.24 354720.0 -69700.0 -0.59 -1.2947 -0.9428 3556002 CMLD3_000096 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCc4ccco4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F13 compound treatment 359200.0 -61300.0 -0.52 450670.0 26200.0 0.22 -0.2114 -0.3731 3556004 CMLD3_000097 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F14 compound treatment 44880.0 -376000.0 -3.2 31380.0 -393000.0 -3.33 -4.6172 -0.9998 3556006 CMLD3_000098 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(Br)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F15 compound treatment 220970.0 -200000.0 -1.7 285200.0 -139000.0 -1.18 -2.0355 -0.9843 3556008 CMLD3_000099 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(F)cc3F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F16 compound treatment 324440.0 -96000.0 -0.82 317980.0 -106000.0 -0.9 -1.2164 -0.9987 3556010 CMLD3_000100 COc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccc(F)cc3F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F17 mock treatment 347780.0 -72700.0 -0.62 462680.0 38200.0 0.32 -0.2081 -0.298 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F18 mock treatment 449120.0 28600.0 0.24 394530.0 -29900.0 -0.25 -0.0072 -0.0206 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F19 compound treatment 395250.0 -25200.0 -0.21 421930.0 -2540.0 -0.02 -0.1669 -0.7741 3556012 CMLD3_000101 COc1ccccc1/C=C/C(O)C(=C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F20 compound treatment 442510.0 22000.0 0.19 492410.0 67900.0 0.58 0.5401 0.8912 3556014 CMLD3_000102 COCn1c2ccccc2c3nnc(nc13)C(=O)OC(C)C#C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F21 compound treatment 267060.0 -153000.0 -1.31 348680.0 -75800.0 -0.64 -1.3774 -0.9468 3556015 CMLD3_000103 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C3(CCCC3=O)C(=O)OCC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F22 compound treatment 325920.0 -94600.0 -0.8 336690.0 -87800.0 -0.74 -1.0953 -0.9993 1952239 CMLD3_000104 O=C1/C(=C/c2ccccc2)/Oc3ccccc13 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F23 compound treatment 422320.0 1850.0 0.02 341250.0 -83200.0 -0.71 -0.488 -0.6912 3556016 CMLD3_000105 Cc1c2OCOc2ccc1O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 F24 compound treatment 424680.0 4210.0 0.04 443860.0 19400.0 0.16 0.1416 0.8413 3556017 CMLD3_000106 COC(=O)N[C@H](C(C(=O)C)C(=O)OC)c1ccc2ccccc2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G01 compound treatment 309660.0 -111000.0 -0.94 490910.0 66400.0 0.56 -0.2681 -0.2441 3556019 CMLD3_000107 COc1ccc2O[C@H]([C@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G02 mock treatment 463360.0 42900.0 0.36 468900.0 44400.0 0.38 0.5245 0.9999 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G03 mock treatment 477380.0 56900.0 0.48 454170.0 29700.0 0.25 0.5205 0.9537 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G04 mock treatment 267330.0 -153000.0 -1.3 354250.0 -70200.0 -0.6 -1.3424 -0.9371 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G05 compound treatment 401440.0 -19000.0 -0.16 391080.0 -33400.0 -0.28 -0.3148 -0.9648 3556020 CMLD3_000108 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G06 compound treatment 438350.0 17900.0 0.15 459540.0 35100.0 0.3 0.3179 0.9515 3556022 CMLD3_000109 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G07 compound treatment 482840.0 62400.0 0.53 427650.0 3180.0 0.03 0.3943 0.7421 3556024 CMLD3_000110 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G08 mock treatment 417150.0 -3320.0 -0.03 444070.0 19600.0 0.17 0.0976 0.5786 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G09 compound treatment 453990.0 33500.0 0.29 446930.0 22500.0 0.19 0.3364 0.9808 3556025 CMLD3_000111 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G10 compound treatment 397920.0 -22600.0 -0.19 372640.0 -51800.0 -0.44 -0.4465 -0.9309 3556027 CMLD3_000112 COc1ccc2C(=O)[C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G11 mock treatment 431470.0 11000.0 0.09 341250.0 -83200.0 -0.71 -0.433 -0.6081 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G12 compound treatment 275360.0 -145000.0 -1.23 225180.0 -199000.0 -1.69 -2.0683 -0.9881 3556029 CMLD3_000113 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G13 compound treatment 445540.0 25100.0 0.21 330560.0 -93900.0 -0.8 -0.4125 -0.5002 3556031 CMLD3_000114 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1Cc2cc(OC)ccc2O[C@H]1c3cccc(OC)c3)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G14 compound treatment 268540.0 -152000.0 -1.29 245640.0 -179000.0 -1.52 -1.9866 -0.9968 3556033 CMLD3_000115 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(Br)cc3)c(c1)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G15 compound treatment 273470.0 -147000.0 -1.25 231560.0 -193000.0 -1.64 -2.0414 -0.9912 3556035 CMLD3_000116 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(cc3)C(C)(C)C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G16 compound treatment 309860.0 -111000.0 -0.94 346050.0 -78400.0 -0.67 -1.1358 -0.9856 3556037 CMLD3_000117 COc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccc(F)cc3F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G17 mock treatment 366290.0 -54200.0 -0.46 454920.0 30500.0 0.26 -0.1433 -0.2711 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G18 compound treatment 82610.0 -338000.0 -2.87 94270.0 -330000.0 -2.8 -4.013 -0.9999 3556038 CMLD3_000118 CC(=C)C(O)/C=C/C=C/c1ccccc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G19 mock treatment 433530.0 13100.0 0.11 378680.0 -45800.0 -0.39 -0.1961 -0.4854 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G20 mock treatment 443150.0 22700.0 0.19 423040.0 -1430.0 -0.01 0.1279 0.6614 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G21 compound treatment 377120.0 -43400.0 -0.37 368160.0 -56300.0 -0.48 -0.5985 -0.9918 3556040 CMLD3_000119 COC(=O)N[C@H](CC(=O)C)c1ccc(Cl)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G22 compound treatment 382670.0 -37800.0 -0.32 425280.0 813.0 0.01 -0.2225 -0.6918 3556042 CMLD3_000120 CCCCCCCC1=CC2=CC(=O)C(C)(OC(=O)C)C(=O)C2=CN1CCc3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G23 compound treatment 412000.0 -8470.0 -0.07 442970.0 18500.0 0.16 0.06 0.3475 3556043 CMLD3_000121 CCCCCCC(=O)Cc1cc(OC)c(OC)cc1C=C(C(=O)OCC)C(=O)OCC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 G24 compound treatment 348570.0 -71900.0 -0.61 426260.0 1790.0 0.02 -0.4218 -0.6893 3556044 CMLD3_000122 CCCCCCC(=O)Cc1cc(OC)c(OC)cc1/C=C(/C(=O)C)\C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H01 compound treatment 428360.0 7890.0 0.07 475760.0 51300.0 0.44 0.3551 0.8066 3556046 CMLD3_000123 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H02 compound treatment 387470.0 -33000.0 -0.28 449830.0 25400.0 0.22 -0.0464 -0.1312 3556048 CMLD3_000124 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H03 mock treatment 434600.0 14100.0 0.12 413840.0 -10600.0 -0.09 0.0212 0.1414 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H04 mock treatment 266990.0 -153000.0 -1.31 432960.0 8490.0 0.07 -0.8723 -0.6671 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H05 compound treatment 321620.0 -98900.0 -0.84 440550.0 16100.0 0.14 -0.4982 -0.5847 3556050 CMLD3_000125 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H](C)C3CCCCC3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H06 compound treatment 287040.0 -133000.0 -1.14 377460.0 -47000.0 -0.4 -1.0846 -0.9015 3556052 CMLD3_000126 COC(=O)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H07 compound treatment 296970.0 -124000.0 -1.05 282620.0 -142000.0 -1.2 -1.5938 -0.9977 3556054 CMLD3_000127 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccco3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H08 compound treatment 493370.0 72900.0 0.62 463200.0 38700.0 0.33 0.6708 0.9559 3556056 CMLD3_000128 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H09 compound treatment 399200.0 -21300.0 -0.18 408060.0 -16400.0 -0.14 -0.2264 -0.9916 3556058 CMLD3_000129 Brc1ccc2O[C@H]([C@H](OC(=O)NCCOc3ccccc3)C(=O)c2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H10 compound treatment 430030.0 9560.0 0.08 400160.0 -24300.0 -0.21 -0.0883 -0.3984 3556060 CMLD3_000130 Fc1ccc(cc1)S(=O)(=O)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H11 compound treatment 362770.0 -57700.0 -0.49 417090.0 -7380.0 -0.06 -0.3914 -0.7908 3556062 CMLD3_000131 COc1ccc2C(=O)[C@@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H12 compound treatment 276510.0 -144000.0 -1.22 449780.0 25300.0 0.21 -0.7142 -0.5744 3556064 CMLD3_000132 COc1ccc2C(=O)[C@H](OC(=O)Nc3ccc(OC(F)F)cc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H13 mock treatment 436160.0 15700.0 0.13 312000.0 -112000.0 -0.95 -0.5802 -0.6023 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H14 compound treatment 5460.0 -415000.0 -3.53 9960.0 -415000.0 -3.52 -4.9828 -1.0 3556065 CMLD3_000133 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(cc2)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H15 compound treatment 461030.0 40600.0 0.35 456740.0 32300.0 0.27 0.4376 0.9934 3556067 CMLD3_000134 Cc1cc(C)cc(C#C[C@H]2O[C@H](CO)[C@@H](Oc3ccc(cc3)C4CCCC4)C=C2)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H16 compound treatment 419680.0 -793.0 -0.01 410560.0 -13900.0 -0.12 -0.0882 -0.7463 3556069 CMLD3_000135 Cc1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/C#Cc3ccc(cc3)C(C)(C)C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H17 compound treatment 316130.0 -104000.0 -0.89 316430.0 -108000.0 -0.92 -1.2757 -0.9999 3556071 CMLD3_000136 CC(=O)c1ccc(cc1)[C@H]2O[C@H](CO)[C@@H](Oc3ccc(F)cc3C)C=C2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H18 compound treatment 448890.0 28400.0 0.24 442920.0 18500.0 0.16 0.2816 0.9779 3556073 CMLD3_000137 Clc1cc2nc3-c4ccccc4OC(CC=C)(c5ccccc5)c3nc2cc1Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H19 mock treatment 386430.0 -34000.0 -0.29 415290.0 -9180.0 -0.08 -0.2598 -0.8664 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H20 mock treatment 415420.0 -5050.0 -0.04 369530.0 -54900.0 -0.47 -0.3599 -0.7691 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H21 compound treatment 5340.0 -415000.0 -3.53 6770.0 -418000.0 -3.54 -5.0027 -1.0 3556074 CMLD3_000138 CCCc1cc2C(=O)[C@H]3O[C@H]3[C@H](O)c2c(=O)o1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H22 compound treatment 403460.0 -17000.0 -0.14 401730.0 -22700.0 -0.19 -0.2387 -0.99 3556076 CMLD3_000139 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccc2ccccc2c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H23 mock treatment 402600.0 -17900.0 -0.15 456660.0 32200.0 0.27 0.0856 0.2738 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 H24 compound treatment 384880.0 -35600.0 -0.3 406590.0 -17900.0 -0.15 -0.3213 -0.9489 3556078 CMLD3_000140 COC(=O)N[C@@H](c1cccc(F)c1)[C@@]2(CCCC2=O)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I01 compound treatment 408880.0 -11600.0 -0.1 505130.0 80700.0 0.68 0.4141 0.599 3556080 CMLD3_000141 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4cc(OC)c(OC)c(OC)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I02 compound treatment 241790.0 -179000.0 -1.52 287310.0 -137000.0 -1.16 -1.8976 -0.9913 3556082 CMLD3_000142 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccco3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I03 compound treatment 385160.0 -35300.0 -0.3 485940.0 61500.0 0.52 0.1563 0.2597 3555962 CMLD3_000143 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I04 mock treatment 440060.0 19600.0 0.17 478900.0 54400.0 0.46 0.4443 0.9052 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I05 mock treatment 368320.0 -52200.0 -0.44 499280.0 74800.0 0.63 0.135 0.1744 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I06 mock treatment 349950.0 -70500.0 -0.6 453380.0 28900.0 0.25 -0.2508 -0.387 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I07 compound treatment 355520.0 -65000.0 -0.55 431940.0 7470.0 0.06 -0.3459 -0.6219 3556084 CMLD3_000144 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccc4OCOc4c3)[C@@H](Oc2c1)c5ccc6OCOc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I08 compound treatment 407610.0 -12900.0 -0.11 376910.0 -47600.0 -0.4 -0.3626 -0.8676 3556086 CMLD3_000145 Brc1ccc2O[C@H]([C@H](OC(=O)NC3CCCC3)C(=O)c2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I09 compound treatment 274120.0 -146000.0 -1.25 438430.0 14000.0 0.12 -0.7966 -0.637 3556088 CMLD3_000146 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I10 compound treatment 433710.0 13200.0 0.11 492960.0 68500.0 0.58 0.4905 0.8287 3556090 CMLD3_000147 CC[C@H](C)[C@@H](NC(=O)O[C@@H]1Cc2cc(Br)ccc2O[C@H]1c3cccc(OC)c3)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I11 compound treatment 290560.0 -130000.0 -1.11 427520.0 3050.0 0.03 -0.7632 -0.6903 3556092 CMLD3_000148 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCc4ccco4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I12 compound treatment 290640.0 -130000.0 -1.1 282010.0 -142000.0 -1.21 -1.6355 -0.999 3556094 CMLD3_000149 CCOC(=O)CNC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I13 compound treatment 80060.0 -340000.0 -2.9 76540.0 -348000.0 -2.95 -4.1347 -1.0 3011535 CMLD3_000150 COCOc1cc(OC)ccc1C(=O)/C=C/c2ccc3OCOc3c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I14 compound treatment 23790.0 -397000.0 -3.37 19260.0 -405000.0 -3.44 -4.8168 -1.0 3556096 CMLD3_000151 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(C)cc2C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I15 compound treatment 410420.0 -10100.0 -0.09 307420.0 -117000.0 -0.99 -0.7625 -0.7652 3556098 CMLD3_000152 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1Oc2ccc(cc2)c3ccccc3)c4ccc(cc4)C(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I16 compound treatment 368050.0 -52400.0 -0.45 476320.0 51900.0 0.44 -0.0043 -0.0069 3556100 CMLD3_000153 Cc1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/C#Cc3ccc(cc3)C(C)(C)C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I17 compound treatment 371930.0 -48500.0 -0.41 476900.0 52400.0 0.44 0.0225 0.0371 3556101 CMLD3_000154 Cc1cc(F)ccc1O[C@H]2C=C[C@@H](CC=C)O[C@@H]2CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I18 compound treatment 423700.0 3230.0 0.03 447390.0 22900.0 0.19 0.1569 0.799 3556103 CMLD3_000155 COC(=O)N(CCc1ccc(OC)c(OC)c1)/C=C/c2ccc(OC)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I19 compound treatment 389500.0 -31000.0 -0.26 394720.0 -29700.0 -0.25 -0.3647 -0.9998 3556105 CMLD3_000156 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)C)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I20 compound treatment 355040.0 -65400.0 -0.56 413190.0 -11300.0 -0.1 -0.4613 -0.8166 3556106 CMLD3_000157 CC(C)(C)OC1C2C3C2C(CC(O)CC=C)C1C3CC(O)CC=C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I21 mock treatment 374150.0 -46300.0 -0.39 434820.0 10400.0 0.09 -0.2166 -0.5364 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I22 mock treatment 450670.0 30200.0 0.26 368570.0 -55900.0 -0.47 -0.1536 -0.2849 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I23 compound treatment 218730.0 -202000.0 -1.72 218180.0 -206000.0 -1.75 -2.4509 -1.0 2119115 CMLD3_000158 COc1ccc(/C=C/C(=O)c2ccc(OC)cc2O)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 I24 compound treatment 436340.0 15900.0 0.13 452050.0 27600.0 0.23 0.2609 0.9658 3556107 CMLD3_000159 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccc(Cl)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J01 compound treatment 408800.0 -11700.0 -0.1 389660.0 -34800.0 -0.3 -0.279 -0.8956 3556109 CMLD3_000160 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J02 compound treatment 209760.0 -211000.0 -1.79 329760.0 -94700.0 -0.8 -1.8356 -0.9345 3556112 CMLD3_000161 CCOC(=O)CNC(=O)O[C@@H]1[C@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J03 compound treatment 257020.0 -163000.0 -1.39 449710.0 25200.0 0.21 -0.8318 -0.5912 3556115 CMLD3_000162 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(Br)cc3C2=O)c4cccc(OC)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J04 mock treatment 327010.0 -93500.0 -0.8 464000.0 39500.0 0.34 -0.3251 -0.3767 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J05 mock treatment 339230.0 -81200.0 -0.69 454310.0 29800.0 0.25 -0.3097 -0.4208 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J06 mock treatment 254200.0 -166000.0 -1.41 353880.0 -70600.0 -0.6 -1.4236 -0.9268 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J07 compound treatment 372860.0 -47600.0 -0.41 260080.0 -164000.0 -1.39 -1.2724 -0.8763 3556117 CMLD3_000163 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCCOc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J08 compound treatment 366580.0 -53900.0 -0.46 433890.0 9420.0 0.08 -0.2677 -0.5751 3556119 CMLD3_000164 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J09 compound treatment 474090.0 53600.0 0.46 443680.0 19200.0 0.16 0.4378 0.9038 3556123 CMLD3_000165 CC[C@H](C)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J10 compound treatment 381250.0 -39200.0 -0.33 341150.0 -83300.0 -0.71 -0.7357 -0.9413 3556129 CMLD3_000166 COc1ccc2O[C@H]([C@H](OC(=O)NS(=O)(=O)c3ccc(F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J11 compound treatment 300270.0 -120000.0 -1.02 338880.0 -85600.0 -0.73 -1.2365 -0.9859 3556130 CMLD3_000167 COc1ccc2O[C@@H]([C@@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J12 compound treatment 335300.0 -85200.0 -0.72 293150.0 -131000.0 -1.11 -1.3 -0.9783 3556132 CMLD3_000168 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCc4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J13 compound treatment 6520.0 -414000.0 -3.52 4090.0 -420000.0 -3.57 -5.0117 -1.0 3556134 CMLD3_000169 COCOc1ccc(OC)cc1C(=O)/C=C/c2ccc(OC)c(Br)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J14 compound treatment 40450.0 -380000.0 -3.23 44000.0 -380000.0 -3.23 -4.5682 -1.0 3556136 CMLD3_000170 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)C#Cc2ccc(F)cc2F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J15 compound treatment 318170.0 -102000.0 -0.87 288190.0 -136000.0 -1.16 -1.4328 -0.9902 3556138 CMLD3_000171 CCOC(=O)OC[C@H]1O[C@@H]([C@@H](C=C1)c2cc(ccc2O)c3ccccc3)c4ccc(cc4)C(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J16 mock treatment 402800.0 -17700.0 -0.15 440320.0 15900.0 0.13 -0.0112 -0.0556 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J17 compound treatment 19110.0 -401000.0 -3.41 17720.0 -407000.0 -3.45 -4.8542 -1.0 3556140 CMLD3_000172 COC(=O)C1(CC(=CCc2ccccc2C1C[N+](=O)[O-])C=C)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J18 mock treatment 454080.0 33600.0 0.29 420160.0 -4310.0 -0.04 0.1763 0.6118 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J19 compound treatment 440330.0 19900.0 0.17 452290.0 27800.0 0.24 0.2863 0.9866 3556141 CMLD3_000173 COc1cccc(/C=C/C(O)C(=C)C)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J20 compound treatment 431860.0 11400.0 0.1 453490.0 29000.0 0.25 0.2426 0.9169 3556143 CMLD3_000174 COC(=O)N1CCc2cc(OC)c(OC)cc2C1Cc3ccc(OC)cc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J21 mock treatment 464340.0 43900.0 0.37 432750.0 8280.0 0.07 0.3136 0.8257 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J22 mock treatment 358900.0 -61600.0 -0.52 443370.0 18900.0 0.16 -0.257 -0.4692 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J23 compound treatment 478960.0 58500.0 0.5 393250.0 -31200.0 -0.26 0.1646 0.292 3556144 CMLD3_000175 CCOC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)OC)c2cccc(C)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 J24 compound treatment 351780.0 -68700.0 -0.58 333930.0 -90500.0 -0.77 -0.9563 -0.9909 3556146 CMLD3_000176 OC[C@@H]1CCCN1C(=O)/C=C/c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K01 compound treatment 444830.0 24400.0 0.21 444800.0 20300.0 0.17 0.2685 0.9958 3556148 CMLD3_000177 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NC4CCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K02 compound treatment 368540.0 -51900.0 -0.44 514670.0 90200.0 0.77 0.2287 0.2588 3556150 CMLD3_000178 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3cccc(c3)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K03 compound treatment 478760.0 58300.0 0.5 502490.0 78000.0 0.66 0.8186 0.9899 3556152 CMLD3_000179 COc1ccc2C(=O)[C@@H](OC(=O)NCc3ccc4OCOc4c3)[C@@H](Oc2c1)c5cccc(c5)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K04 mock treatment 406720.0 -13800.0 -0.12 502740.0 78300.0 0.66 0.3868 0.5737 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K05 compound treatment 349810.0 -70700.0 -0.6 434400.0 9930.0 0.08 -0.3655 -0.6021 3011485 CMLD3_000180 COc1ccc2C(=O)[C@@H](O)[C@@H](Oc2c1)c3cccc(c3)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K06 compound treatment 378350.0 -42100.0 -0.36 401440.0 -23000.0 -0.2 -0.3915 -0.9593 3556154 CMLD3_000181 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K07 mock treatment 430760.0 10300.0 0.09 521700.0 97200.0 0.82 0.6451 0.7778 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K08 mock treatment 405120.0 -15400.0 -0.13 533520.0 109000.0 0.93 0.5618 0.6013 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K09 compound treatment 422200.0 1730.0 0.01 420800.0 -3670.0 -0.03 -0.0116 -0.3373 3556156 CMLD3_000182 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K10 compound treatment 381370.0 -39100.0 -0.33 409050.0 -15400.0 -0.13 -0.3277 -0.9168 3556158 CMLD3_000183 COc1ccc2O[C@H]([C@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K11 compound treatment 373830.0 -46600.0 -0.4 343200.0 -81300.0 -0.69 -0.768 -0.9656 3556159 CMLD3_000184 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCCc4ccc(OC)c(OC)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K12 compound treatment 356160.0 -64300.0 -0.55 349960.0 -74500.0 -0.63 -0.8338 -0.9974 3556161 CMLD3_000185 COc1ccc2O[C@H]([C@H](OC(=O)NCc3ccc4OCOc4c3)C(=O)c2c1)c5ccc(OC)c(Br)c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K13 mock treatment 436600.0 16100.0 0.14 498250.0 73800.0 0.63 0.5396 0.8421 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K14 compound treatment 498670.0 78200.0 0.67 514190.0 89700.0 0.76 1.0086 0.9977 3556162 CMLD3_000186 CC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)C)c2cc(C)cc(C)c2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K15 mock treatment 433370.0 12900.0 0.11 517210.0 92700.0 0.79 0.6339 0.798 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K16 mock treatment 417640.0 -2830.0 -0.02 494720.0 70300.0 0.6 0.4044 0.678 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K17 compound treatment 477320.0 56800.0 0.48 398460.0 -26000.0 -0.22 0.186 0.3499 3556164 CMLD3_000187 COC(=O)N[C@H](CC(=O)C)c1cccc(C)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K18 compound treatment 526080.0 106000.0 0.9 501680.0 77200.0 0.65 1.0984 0.9879 3556166 CMLD3_000188 COC(=O)N[C@H](CC(=O)C)c1ccco1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K19 compound treatment 461720.0 41200.0 0.35 476900.0 52400.0 0.44 0.5626 0.9931 3556168 CMLD3_000189 COc1ccc(OC)c(c1)[C@@H]2OCCC=C[C@H]2C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K20 compound treatment 410240.0 -10200.0 -0.09 464340.0 39900.0 0.34 0.1776 0.5085 3556170 CMLD3_000190 CC1=C(C)CC(C(C1)C(=O)c2ccccc2O)c3ccccc3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K21 mock treatment 487770.0 67300.0 0.57 424200.0 -267.0 0.0 0.4032 0.7043 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K22 compound treatment 350760.0 -69700.0 -0.59 378920.0 -45500.0 -0.39 -0.6926 -0.9784 3556171 CMLD3_000191 CCCCCCC1=Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)C)C(=O)OCC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K23 mock treatment 383040.0 -37400.0 -0.32 438740.0 14300.0 0.12 -0.1396 -0.4097 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 K24 mock treatment 457310.0 36800.0 0.31 398100.0 -26400.0 -0.22 0.0634 0.1648 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L01 mock treatment 346050.0 -74400.0 -0.63 457390.0 32900.0 0.28 -0.2502 -0.3616 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L02 compound treatment 296420.0 -124000.0 -1.06 469860.0 45400.0 0.39 -0.474 -0.4219 3556172 CMLD3_000192 COc1ccc2O[C@H]([C@H](OC(=O)NCc3ccco3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L03 mock treatment 478190.0 57700.0 0.49 455880.0 31400.0 0.27 0.5356 0.9588 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L04 mock treatment 437960.0 17500.0 0.15 360930.0 -63500.0 -0.54 -0.2759 -0.4935 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L05 compound treatment 332160.0 -88300.0 -0.75 409440.0 -15000.0 -0.13 -0.6214 -0.8154 3556173 CMLD3_000193 O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3ccc4OCOc4c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L06 compound treatment 439090.0 18600.0 0.16 396990.0 -27500.0 -0.23 -0.0528 -0.1874 3556175 CMLD3_000194 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)Nc4ccc(OC(F)F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L07 mock treatment 450630.0 30200.0 0.26 433560.0 9090.0 0.08 0.236 0.8808 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L08 mock treatment 458930.0 38500.0 0.33 403050.0 -21400.0 -0.18 0.1029 0.2749 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L09 compound treatment 434570.0 14100.0 0.12 460450.0 36000.0 0.31 0.3006 0.9167 3556177 CMLD3_000195 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NS(=O)(=O)c4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L10 compound treatment 429280.0 8810.0 0.07 491380.0 66900.0 0.57 0.4543 0.7936 3556179 CMLD3_000196 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)Nc4ccc(C)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L11 compound treatment 409710.0 -10800.0 -0.09 405670.0 -18800.0 -0.16 -0.1775 -0.9653 3556181 CMLD3_000197 COC(=O)[C@@H](NC(=O)O[C@@H]1[C@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L12 compound treatment 428520.0 8050.0 0.07 415760.0 -8710.0 -0.07 -0.0038 -0.0379 3556182 CMLD3_000198 COc1ccc2C(=O)[C@H](OC(=O)NCc3ccc4OCOc4c3)[C@H](Oc2c1)c5ccc6OCOc6c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L13 compound treatment 15110.0 -405000.0 -3.45 31140.0 -393000.0 -3.34 -4.7977 -0.9999 3556183 CMLD3_000199 CCCCCCC#C[C@H]1O[C@H](COC(=O)C)[C@@H](OC(=O)C)C=C1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L14 compound treatment 34100.0 -386000.0 -3.29 39420.0 -385000.0 -3.27 -4.6338 -1.0 3556185 CMLD3_000200 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(cc2)C(C)(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L15 mock treatment 490340.0 69900.0 0.59 333170.0 -91300.0 -0.77 -0.1273 -0.1304 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L16 mock treatment 454790.0 34300.0 0.29 427450.0 2980.0 0.03 0.2243 0.7655 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L17 compound treatment 305560.0 -115000.0 -0.98 253780.0 -171000.0 -1.45 -1.7151 -0.9817 3556187 CMLD3_000201 COC(=O)CC1=CO[C@@H](O)[C@H]2[C@@H]1CC=C2CO 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L18 compound treatment 73620.0 -347000.0 -2.95 58880.0 -366000.0 -3.1 -4.2794 -0.9997 3556189 CMLD3_000202 COC(=O)C1=NOC2(C1)C=C(Br)C(=C(Br)C2=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L19 compound treatment 360740.0 -59700.0 -0.51 420760.0 -3710.0 -0.03 -0.3816 -0.7494 3556190 CMLD3_000203 O=C1OC(=NC21CC2)C3=CCCCC3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L20 mock treatment 458600.0 38100.0 0.32 482300.0 57800.0 0.49 0.5763 0.9798 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L21 compound treatment 449090.0 28600.0 0.24 452720.0 28300.0 0.24 0.3416 1.0 3556191 CMLD3_000204 CCCCCCC1Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)OCC)C(=O)OCC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L22 compound treatment 368760.0 -51700.0 -0.44 431460.0 6990.0 0.06 -0.2691 -0.6063 3556192 CMLD3_000205 COC(=O)[C@@H](OCc1ccccc1)/C=C/[C@H](C)Cc2cc(Br)cc(OCc3ccccc3)c2OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L23 mock treatment 406320.0 -14200.0 -0.12 471150.0 46700.0 0.4 0.1949 0.4708 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 L24 mock treatment 471850.0 51400.0 0.44 458240.0 33800.0 0.29 0.5116 0.979 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M01 mock treatment 431000.0 10500.0 0.09 485680.0 61200.0 0.52 0.4305 0.817 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M02 compound treatment 452760.0 32300.0 0.27 496570.0 72100.0 0.61 0.6267 0.9347 3556194 CMLD3_000206 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3ccc(OC)c(Br)c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M03 compound treatment 451970.0 31500.0 0.27 455280.0 30800.0 0.26 0.3743 0.9999 3556196 CMLD3_000207 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2ccc(Br)cc2C1=O)c3cccc(OC)c3)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M04 compound treatment 467200.0 46700.0 0.4 452390.0 27900.0 0.24 0.4486 0.9694 3556198 CMLD3_000208 COc1ccc2C(=O)[C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M05 compound treatment 456520.0 36000.0 0.31 481340.0 56900.0 0.48 0.558 0.9761 3556199 CMLD3_000209 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M06 compound treatment 413870.0 -6600.0 -0.06 417500.0 -6970.0 -0.06 -0.0815 -0.9997 3556201 CMLD3_000210 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)N[C@H](C)C4CCCCC4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M07 compound treatment 496920.0 76400.0 0.65 427320.0 2850.0 0.02 0.477 0.7329 3556203 CMLD3_000211 COc1ccc2C(=O)[C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)[C@@H](Oc2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M08 compound treatment 508900.0 88400.0 0.75 493250.0 68800.0 0.58 0.9445 0.9921 3556205 CMLD3_000212 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(OC)cc3C2=O)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M09 mock treatment 486830.0 66400.0 0.56 504690.0 80200.0 0.68 0.8804 0.9957 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M10 mock treatment 515870.0 95400.0 0.81 517300.0 92800.0 0.79 1.1307 0.9999 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M11 compound treatment 455700.0 35200.0 0.3 500800.0 76300.0 0.65 0.6698 0.9387 3556206 CMLD3_000213 COc1ccc2O[C@@H]([C@@H](OC(=O)NCCc3ccc(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M12 compound treatment 412270.0 -8200.0 -0.07 453570.0 29100.0 0.25 0.1252 0.4881 2060493 CMLD3_000214 COc1ccc2c(=O)c(coc2c1)c3ccc4OCOc4c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M13 mock treatment 483930.0 63500.0 0.54 500980.0 76500.0 0.65 0.8407 0.9958 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M14 mock treatment 498010.0 77500.0 0.66 443740.0 19300.0 0.16 0.582 0.8564 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M15 mock treatment 509640.0 89200.0 0.76 463390.0 38900.0 0.33 0.7699 0.9306 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M16 mock treatment 504120.0 83600.0 0.71 466260.0 41800.0 0.35 0.7539 0.9482 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M17 compound treatment 475720.0 55200.0 0.47 508920.0 84500.0 0.72 0.8389 0.9791 3556208 CMLD3_000215 COC(=O)N[C@@H](c1ccccc1)[C@@]2(CCCC2=O)C(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M18 compound treatment 339110.0 -81400.0 -0.69 458680.0 34200.0 0.29 -0.2842 -0.3787 3556210 CMLD3_000216 COc1ccc(/C=C/NC(=O)Cc2ccc(OC)c(OC)c2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M19 compound treatment 405210.0 -15300.0 -0.13 456490.0 32000.0 0.27 0.1003 0.333 3556212 CMLD3_000217 CCOP(=O)(CC(C(O)c1ccccc1)C(=O)C)OCC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M20 compound treatment 417220.0 -3250.0 -0.03 392930.0 -31500.0 -0.27 -0.2087 -0.7761 3556213 CMLD3_000218 CCOC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)OC)/C=C/c2ccco2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M21 compound treatment 450310.0 29800.0 0.25 462560.0 38100.0 0.32 0.408 0.9929 3556215 CMLD3_000219 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(O)(c4cc(cc(c4)C(F)(F)F)C(F)(F)F)c5cc(cc(c5)C(F)(F)F)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M22 compound treatment 413620.0 -6850.0 -0.06 432690.0 8220.0 0.07 0.0081 0.0891 3556217 CMLD3_000220 COC(=O)[C@]1(CCCC1=O)[C@@H](NC(=O)O/C=C/C)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M23 compound treatment 409600.0 -10900.0 -0.09 409710.0 -14800.0 -0.13 -0.1539 -0.9889 3556219 CMLD3_000221 CC1(O)C(=O)C=C2C=C(CCCCOCc3ccccc3)OC=C2C1=O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 M24 compound treatment 388730.0 -31700.0 -0.27 397480.0 -27000.0 -0.23 -0.3528 -0.9966 3556220 CMLD3_000222 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N01 compound treatment 339150.0 -81300.0 -0.69 439900.0 15400.0 0.13 -0.3966 -0.5633 3556222 CMLD3_000223 COc1ccc2C(=O)[C@@H](OC(=O)Nc3cc(OC)c(OC)c(OC)c3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N02 mock treatment 406850.0 -13600.0 -0.12 453340.0 28900.0 0.24 0.0912 0.3367 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N03 compound treatment 490290.0 69800.0 0.59 468160.0 43700.0 0.37 0.6821 0.9742 3556224 CMLD3_000224 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3ccc(OC(F)F)cc3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N04 compound treatment 197310.0 -223000.0 -1.9 209130.0 -215000.0 -1.83 -2.6341 -0.9998 3556226 CMLD3_000225 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3[C@H](O)[C@H]2O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N05 compound treatment 292680.0 -128000.0 -1.09 299270.0 -125000.0 -1.06 -1.5197 -0.9999 3556228 CMLD3_000226 COc1ccc2O[C@@H]([C@@H](O)C(=O)c2c1)c3ccc(OC)c(Br)c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N06 compound treatment 494660.0 74200.0 0.63 470650.0 46200.0 0.39 0.7233 0.9737 3556229 CMLD3_000227 COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@H]2[C@@H](Oc3ccc(OC)cc3C2=O)c4cccc(OC)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N07 compound treatment 482400.0 61900.0 0.53 452570.0 28100.0 0.24 0.5411 0.9357 3556231 CMLD3_000228 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)NCCc4ccc(OC)c(OC)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N08 compound treatment 468080.0 47600.0 0.41 486400.0 61900.0 0.53 0.6579 0.9917 3556233 CMLD3_000229 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2OC(=O)NCCOc4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N09 mock treatment 405980.0 -14500.0 -0.12 387890.0 -36600.0 -0.31 -0.3066 -0.9183 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N10 mock treatment 484080.0 63600.0 0.54 489130.0 64700.0 0.55 0.7705 1.0 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N11 mock treatment 451850.0 31400.0 0.27 506650.0 82200.0 0.7 0.6817 0.9132 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N12 compound treatment 424890.0 4420.0 0.04 462490.0 38000.0 0.32 0.2546 0.7842 3556235 CMLD3_000230 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2OC(=O)NCc4ccco4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N13 mock treatment 493600.0 73100.0 0.62 485160.0 60700.0 0.51 0.804 0.9956 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N14 mock treatment 496750.0 76300.0 0.65 509360.0 84900.0 0.72 0.9681 0.9986 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N15 compound treatment 503520.0 83000.0 0.71 501400.0 76900.0 0.65 0.961 0.9992 3556237 CMLD3_000231 CC(=O)c1ccc(O[C@@H]2[C@H](O)CO[C@@H]2/C=C/c3ccc(Cl)cc3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N16 compound treatment 110520.0 -310000.0 -2.64 146000.0 -278000.0 -2.36 -3.5348 -0.9985 3556239 CMLD3_000232 CCCCC#C[C@H]1O[C@H](CO)[C@@H](Oc2ccc(OC)cc2)C=C1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N17 compound treatment 460660.0 40200.0 0.34 394270.0 -30200.0 -0.26 0.0606 0.1419 3556241 CMLD3_000233 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1cccc(c1)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N18 compound treatment 459040.0 38600.0 0.33 459770.0 35300.0 0.3 0.4438 0.999 3556243 CMLD3_000234 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1cccs1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N19 compound treatment 457320.0 36800.0 0.31 482490.0 58000.0 0.49 0.5697 0.9763 3556191 CMLD3_000235 CCCCCCC1Cc2cc(OC)c(OC)cc2C(O1)C(C(=O)OCC)C(=O)OCC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N20 compound treatment 380230.0 -40200.0 -0.34 413880.0 -10600.0 -0.09 -0.3056 -0.8634 3556245 CMLD3_000236 COc1ccc(/C=C/N(CCc2ccc(OC)c(OC)c2)C(=O)C)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N21 mock treatment 466410.0 45900.0 0.39 438560.0 14100.0 0.12 0.3609 0.883 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N22 compound treatment 431870.0 11400.0 0.1 454270.0 29800.0 0.25 0.2473 0.9134 3556247 CMLD3_000237 CCC1(CC2(CC)C(CC1=O)c3ccccc3)C=C2/C=C/c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N23 compound treatment 394090.0 -26400.0 -0.22 433340.0 8870.0 0.08 -0.1055 -0.4456 3556249 CMLD3_000238 CC1(CC2(C)C(CC1=O)c3ccc(F)cc3)C=C2/C=C/c4ccc(F)cc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 N24 mock treatment 456410.0 35900.0 0.31 421550.0 -2920.0 -0.02 0.1987 0.6478 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O01 compound treatment 469930.0 49500.0 0.42 458160.0 33700.0 0.29 0.4996 0.9822 3556251 CMLD3_000239 COc1ccc2O[C@@H]([C@@H](OC(=O)N[C@H](C)C3CCCCC3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O02 compound treatment 367770.0 -52700.0 -0.45 430730.0 6260.0 0.05 -0.2795 -0.619 3556253 CMLD3_000240 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3ccc4OCOc4c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O03 compound treatment 253620.0 -167000.0 -1.42 426690.0 2220.0 0.02 -0.9904 -0.6977 3556254 CMLD3_000241 COc1ccc2C(=O)[C@@H](OC(=O)N[C@H]3CCCc4ccccc34)[C@@H](Oc2c1)c5cccc(c5)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O04 compound treatment 293970.0 -127000.0 -1.08 442100.0 17600.0 0.15 -0.6552 -0.603 3556256 CMLD3_000242 COc1ccc2C(=O)[C@H](OC(=O)Nc3ccc(C)c(Br)c3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O05 compound treatment 291370.0 -129000.0 -1.1 296570.0 -128000.0 -1.08 -1.5438 -1.0 3131449 CMLD3_000243 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O06 compound treatment 396540.0 -23900.0 -0.2 425460.0 993.0 0.01 -0.138 -0.6773 3556257 CMLD3_000244 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C(=O)[C@H]2OC(=O)N[C@H]4CCCc5ccccc45 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O07 mock treatment 393620.0 -26900.0 -0.23 384190.0 -40300.0 -0.34 -0.4031 -0.9808 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O08 mock treatment 322900.0 -97600.0 -0.83 435610.0 11100.0 0.09 -0.5201 -0.6226 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O09 mock treatment 420210.0 -263.0 0.0 473980.0 49500.0 0.42 0.2954 0.7033 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O10 compound treatment 458640.0 38200.0 0.32 429920.0 5450.0 0.05 0.2623 0.7998 3556259 CMLD3_000245 COc1cccc(c1)[C@@H]2Oc3ccc(OC)cc3C[C@H]2O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O11 mock treatment 417850.0 -2620.0 -0.02 355210.0 -69300.0 -0.59 -0.4312 -0.7334 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O12 mock treatment 440490.0 20000.0 0.17 466600.0 42100.0 0.36 0.3731 0.9425 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O13 compound treatment 20740.0 -400000.0 -3.4 31590.0 -393000.0 -3.33 -4.7612 -0.9999 3556261 CMLD3_000246 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O14 compound treatment 21130.0 -399000.0 -3.4 20560.0 -404000.0 -3.43 -4.825 -1.0 3556263 CMLD3_000247 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(C)cc2C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O15 compound treatment 420570.0 97.3 0.0 407330.0 -17100.0 -0.15 -0.1022 -0.7031 3556265 CMLD3_000248 CC(=O)c1ccc(O[C@@H]2[C@H](O)CO[C@H]2/C=C/c3ccc(Cl)cc3)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O16 compound treatment 114340.0 -306000.0 -2.6 137860.0 -287000.0 -2.43 -3.5607 -0.9994 3556008 CMLD3_000249 COc1ccc(O[C@H]2C=C[C@H](O[C@@H]2CO)C#Cc3ccc(F)cc3F)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O17 compound treatment 419680.0 -793.0 -0.01 416480.0 -7990.0 -0.07 -0.0527 -0.7737 3556266 CMLD3_000250 CC(=CCC1(CC=C(C)C)C(=O)C(=C2OC(C)(C)CCC2(CC=C(C)C)C1=O)C(=O)c3ccccc3)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O18 compound treatment 370510.0 -50000.0 -0.43 350760.0 -73700.0 -0.63 -0.7427 -0.9823 3556267 CMLD3_000251 CC1(CC2(C)C(CC1=O)/C=C/c3ccccc3)C=C2/C=C/C=C/c4ccccc4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O19 compound treatment 401840.0 -18600.0 -0.16 429810.0 5340.0 0.05 -0.08 -0.4855 1125649 CMLD3_000252 CNc1ccccc1C(=O)OCC(=O)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O20 mock treatment 447850.0 27400.0 0.23 424420.0 -46.7 0.0 0.1644 0.7059 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O21 mock treatment 397600.0 -22900.0 -0.19 416330.0 -8140.0 -0.07 -0.1864 -0.9028 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O22 compound treatment 439470.0 19000.0 0.16 408830.0 -15600.0 -0.13 0.0205 0.098 3556269 CMLD3_000253 CNc1ccccc1C(=O)OCC(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O23 compound treatment 388410.0 -32100.0 -0.27 339880.0 -84600.0 -0.72 -0.7002 -0.9122 3556270 CMLD3_000254 COc1ccc(/C=C/NC(=O)c2ccc(OC)cc2)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 O24 compound treatment 364190.0 -56300.0 -0.48 367370.0 -57100.0 -0.48 -0.681 -1.0 3556272 CMLD3_000255 COC(=O)N[C@H](/C(=C(\C)/NCc1ccccc1)/C(=O)OC)c2ccc(Cl)cc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P01 compound treatment 201890.0 -219000.0 -1.86 362300.0 -62200.0 -0.53 -1.6878 -0.8732 3556274 CMLD3_000256 COC(=O)[C@@H](NC(=O)O[C@H]1[C@@H](Oc2cc(OC)ccc2C1=O)c3cccc(c3)C(F)(F)F)C(C)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P02 mock treatment 224290.0 -196000.0 -1.67 357290.0 -67200.0 -0.57 -1.5831 -0.8977 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P03 mock treatment 341780.0 -78700.0 -0.67 368640.0 -55800.0 -0.47 -0.8082 -0.9856 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P04 compound treatment 242600.0 -178000.0 -1.51 298000.0 -126000.0 -1.07 -1.8286 -0.9858 3556276 CMLD3_000257 COc1ccc2O[C@@H]([C@@H](OC(=O)Nc3ccc(C)c(Br)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P05 compound treatment 214400.0 -206000.0 -1.75 201060.0 -223000.0 -1.9 -2.5797 -0.9992 3011477 CMLD3_000258 COc1cccc(c1)[C@@H]2Oc3ccc(Br)cc3C(=O)[C@H]2O 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P06 compound treatment 304050.0 -116000.0 -0.99 340990.0 -83500.0 -0.71 -1.2011 -0.9865 3556277 CMLD3_000259 COC(=O)[C@H](COC(C)(C)C)NC(=O)O[C@H]1[C@@H](Oc2ccc(OC)cc2C1=O)c3cccc(OC)c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P07 compound treatment 366520.0 -54000.0 -0.46 276880.0 -148000.0 -1.25 -1.2098 -0.9073 3556279 CMLD3_000260 COc1ccc2O[C@H]([C@H](OC(=O)NCCc3ccc(OC)c(OC)c3)C(=O)c2c1)c4ccc(OC)c(Br)c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P08 compound treatment 241120.0 -179000.0 -1.53 268070.0 -156000.0 -1.33 -2.017 -0.9976 3556280 CMLD3_000261 COc1ccc2C(=O)[C@@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)[C@@H](Oc2c1)c4cccc(c4)C(F)(F)F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P09 mock treatment 338100.0 -82400.0 -0.7 317050.0 -107000.0 -0.91 -1.1398 -0.9916 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P10 compound treatment 266160.0 -154000.0 -1.31 375770.0 -48700.0 -0.41 -1.2204 -0.8867 3556282 CMLD3_000262 COc1ccc2C(=O)[C@H](OC(=O)NS(=O)(=O)c3ccc(C)cc3)[C@H](Oc2c1)c4ccc5OCOc5c4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P11 mock treatment 290670.0 -130000.0 -1.1 287360.0 -137000.0 -1.16 -1.6032 -0.9997 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P12 mock treatment 333320.0 -87200.0 -0.74 341320.0 -83100.0 -0.71 -1.023 -0.9997 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P13 compound treatment 186000.0 -234000.0 -1.99 326090.0 -98400.0 -0.83 -2.0006 -0.9252 3556284 CMLD3_000263 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)c2ccccc2 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P14 compound treatment 17060.0 -403000.0 -3.43 13330.0 -411000.0 -3.49 -4.8928 -1.0 3556286 CMLD3_000264 CCOC(=O)OC[C@H]1O[C@@H](C=C[C@@H]1OC(=O)OCC)C#Cc2ccc(F)cc2F 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P15 compound treatment 317440.0 -103000.0 -0.88 401310.0 -23200.0 -0.2 -0.7587 -0.8446 3556288 CMLD3_000265 Cc1cc(C)cc(/C=C/[C@@H]2OC[C@@H](O)[C@H]2Oc3ccc(cc3)C4CCCC4)c1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P16 compound treatment 195250.0 -225000.0 -1.92 277370.0 -147000.0 -1.25 -2.2372 -0.9784 3556289 CMLD3_000266 Cc1cc(F)ccc1O[C@H]2C=C[C@H](O[C@@H]2CO)c3ccc4OCOc4c3 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P17 compound treatment 352280.0 -68200.0 -0.58 326690.0 -97800.0 -0.83 -0.9967 -0.9847 3556073 CMLD3_000267 Clc1cc2nc3-c4ccccc4OC(CC=C)(c5ccccc5)c3nc2cc1Cl 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P18 compound treatment 247230.0 -173000.0 -1.47 354010.0 -70500.0 -0.6 -1.4648 -0.921 3556291 CMLD3_000268 COc1ccc(cc1)C(=O)Oc2cc(OC)cc(OC)c2C(=O)C 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P19 compound treatment 313440.0 -107000.0 -0.91 309280.0 -115000.0 -0.98 -1.3348 -0.9994 3556292 CMLD3_000269 CC(=C)C(O)/C=C/c1ccc(Br)cc1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P20 mock treatment 330770.0 -89700.0 -0.76 309410.0 -115000.0 -0.98 -1.2297 -0.9926 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P21 compound treatment 231360.0 -189000.0 -1.61 268580.0 -156000.0 -1.32 -2.0727 -0.9953 3556294 CMLD3_000270 COC(=O)N[C@@H](/C=C/c1ccco1)[C@@]2(CCCC2=O)C(=O)OC 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P22 compound treatment 240720.0 -180000.0 -1.53 217360.0 -207000.0 -1.76 -2.3236 -0.9976 3556296 CMLD3_000271 CC1(C)O[C@H]([C@@H](O1)C(O)(c2cc(F)c(F)c(F)c2)c3cc(F)c(F)c(F)c3)C(O)(c4cc(F)c(F)c(F)c4)c5cc(F)c(F)c(F)c5 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P23 compound treatment 263840.0 -157000.0 -1.33 273120.0 -151000.0 -1.28 -1.85 -0.9998 3556298 CMLD3_000272 COC(=O)N[C@H](C(C(=O)C)C(=O)OCC=C)c1ccco1 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.2284 P24 mock treatment 334410.0 -86100.0 -0.73 267860.0 -157000.0 -1.33 -1.4571 -0.9606 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A01 mock treatment 484930.0 -57500.0 -0.49 450770.0 -90900.0 -0.77 -0.3186 -0.2689 395440.0 -20018.505434783 -0.121738798714694 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A02 mock treatment 517040.0 -25400.0 -0.22 480410.0 -61300.0 -0.52 -0.9646 -0.7588 406400.0 -9058.505434783 -0.0550876074826694 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A03 mock treatment 504890.0 -37500.0 -0.32 495430.0 -46300.0 -0.39 -1.4002 -0.8926 226000.0 -189458.505434783 -1.15215648506089 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A04 mock treatment 554240.0 11800.0 0.1 311320.0 -230000.0 -1.95 -0.472 -0.2271 457670.0 42211.494565217 0.256701313545242 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A05 mock treatment 512720.0 -29700.0 -0.25 567120.0 25400.0 0.22 -1.028 -0.6029 148160.0 -267298.505434783 -1.62552589432191 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A06 mock treatment 588090.0 45700.0 0.39 558810.0 17100.0 0.15 0.3538 0.7921 416820.0 1361.494565217 0.00827967469230296 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A07 mock treatment 480010.0 -62400.0 -0.53 433660.0 -108000.0 -0.92 -0.7084 -0.6189 367540.0 -47918.505434783 -0.291407433329063 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A08 mock treatment 548120.0 5700.0 0.05 385660.0 -156000.0 -1.32 -0.5142 -0.3752 471400.0 55941.494565217 0.340197741977331 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A09 mock treatment 540670.0 -1750.0 -0.01 534120.0 -7570.0 -0.06 -0.1031 -0.1507 483490.0 68031.494565217 0.413720816976891 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A10 mock treatment 560580.0 18200.0 0.15 494910.0 -46800.0 -0.4 -0.0506 -0.0807 479290.0 63831.494565217 0.388179302088706 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A11 mock treatment 348960.0 -193000.0 -1.65 391090.0 -151000.0 -1.28 -1.4957 -0.7075 451150.0 35691.494565217 0.217051152337869 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A12 mock treatment 558910.0 16500.0 0.14 558570.0 16900.0 0.14 0.1832 0.7328 438270.0 22811.494565217 0.138723840014103 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A13 mock treatment 551970.0 9550.0 0.08 630210.0 88500.0 0.75 -0.579 -0.3312 169150.0 -246308.505434783 -1.49787913301167 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A14 mock treatment 549020.0 6600.0 0.06 556920.0 15200.0 0.13 -0.5285 -0.594 312330.0 -103128.505434783 -0.627156727847319 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A15 mock treatment 433820.0 -109000.0 -0.92 584840.0 43200.0 0.37 -0.1972 -0.1893 395160.0 -20298.505434783 -0.123441566373906 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A16 mock treatment 546020.0 3600.0 0.03 523700.0 -18000.0 -0.15 -0.4295 -0.5548 418910.0 3451.494565217 0.0209896190057091 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A17 mock treatment 485940.0 -56500.0 -0.48 476810.0 -64900.0 -0.55 -0.0986 -0.1043 496480.0 81021.494565217 0.492717073738205 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A18 mock treatment 502360.0 -40100.0 -0.34 371620.0 -170000.0 -1.44 -0.8693 -0.551 481880.0 66421.494565217 0.40392990293642 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A19 mock treatment 536610.0 -5810.0 -0.05 536170.0 -5520.0 -0.05 0.1009 0.4557 440080.0 24621.494565217 0.149731016668297 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A20 mock treatment 509850.0 -32600.0 -0.28 507580.0 -34100.0 -0.29 -0.4328 -0.4461 490610.0 75151.494565217 0.457019766025433 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A21 mock treatment 442270.0 -100000.0 -0.85 507550.0 -34100.0 -0.29 -0.1662 -0.1522 454780.0 39321.494565217 0.239126318776943 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A22 mock treatment 531250.0 -11200.0 -0.1 326400.0 -215000.0 -1.83 -0.5881 -0.3089 469600.0 54141.494565217 0.329251378453823 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A23 mock treatment 420410.0 -122000.0 -1.04 505630.0 -36100.0 -0.31 -0.4625 -0.4087 467010.0 51551.494565217 0.313500777606109 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base A24 mock treatment 507900.0 -34500.0 -0.29 319450.0 -222000.0 -1.89 -1.0246 -0.5165 488340.0 72881.494565217 0.443215185359676 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B01 mock treatment 558880.0 16500.0 0.14 547070.0 5380.0 0.05 0.2812 0.8695 459140.0 43681.494565217 0.265640843756106 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B02 mock treatment 573940.0 31500.0 0.27 488020.0 -53700.0 -0.46 0.2884 0.3808 472390.0 56931.494565217 0.34621824191526 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B03 mock treatment 573670.0 31200.0 0.27 609310.0 67600.0 0.57 0.4224 0.6044 450490.0 35031.494565217 0.213037485712583 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B04 mock treatment 589280.0 46900.0 0.4 543130.0 1440.0 0.01 0.6787 0.8675 485040.0 69581.494565217 0.423146852233245 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B05 mock treatment 559780.0 17400.0 0.15 491540.0 -50100.0 -0.43 0.1811 0.2828 462270.0 46811.494565217 0.284675353660872 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B06 mock treatment 551200.0 8780.0 0.07 526930.0 -14800.0 -0.13 -0.0252 -0.1527 406400.0 -9058.505434783 -0.0550876074826694 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B07 mock treatment 579700.0 37300.0 0.32 498830.0 -42900.0 -0.36 0.209 0.3563 446720.0 31261.494565217 0.190110935443903 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B08 mock treatment 575440.0 33000.0 0.28 567040.0 25400.0 0.22 0.4463 0.6864 502470.0 87011.494565217 0.529144139019211 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B09 mock treatment 553760.0 11300.0 0.1 503680.0 -38000.0 -0.32 0.1975 0.331 492540.0 77081.494565217 0.46875670024786 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B10 mock treatment 574260.0 31800.0 0.27 562080.0 20400.0 0.17 0.5207 0.9113 489170.0 73711.494565217 0.448262675206626 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B11 mock treatment 539360.0 -3060.0 -0.03 538560.0 -3130.0 -0.03 0.2456 0.379 399680.0 -15778.505434783 -0.0959540313037648 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B12 mock treatment 585760.0 43300.0 0.37 420920.0 -121000.0 -1.02 -0.6848 -0.4994 433920.0 18461.494565217 0.112270128165626 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B13 mock treatment 573500.0 31100.0 0.26 545370.0 3680.0 0.03 0.4167 0.8283 437120.0 21661.494565217 0.131730329985195 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B14 mock treatment 578260.0 35800.0 0.3 545500.0 3810.0 0.03 -0.308 -0.4158 335360.0 -80098.505434783 -0.487104087877107 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B15 mock treatment 575160.0 32700.0 0.28 566340.0 24700.0 0.21 0.3904 0.9628 438200.0 22741.494565217 0.1382981480993 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B16 mock treatment 575520.0 33100.0 0.28 585300.0 43600.0 0.37 0.6876 0.969 493530.0 78071.494565217 0.474777200185789 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B17 mock treatment 507640.0 -34800.0 -0.3 590670.0 49000.0 0.42 0.1944 0.3178 470020.0 54561.494565217 0.331805529942642 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B18 mock treatment 529190.0 -13200.0 -0.11 493290.0 -48400.0 -0.41 0.2548 0.3013 498080.0 82621.494565217 0.502447174647989 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B19 mock treatment 510050.0 -32400.0 -0.28 560280.0 18600.0 0.16 -0.6452 -0.7242 310570.0 -104888.505434783 -0.637859838848082 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B20 mock treatment 548660.0 6240.0 0.05 520190.0 -21500.0 -0.18 -0.2578 -0.3335 464820.0 49361.494565217 0.300182701985842 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B21 mock treatment 571470.0 29000.0 0.25 414670.0 -127000.0 -1.08 -0.0188 -0.015 459940.0 44481.494565217 0.270505894210999 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B22 mock treatment 564660.0 22200.0 0.19 492410.0 -49300.0 -0.42 -0.0426 -0.0748 464480.0 49021.494565217 0.298115055542512 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B23 mock treatment 571400.0 29000.0 0.25 513820.0 -27900.0 -0.24 0.0868 0.1312 364390.0 -51068.505434783 -0.310563569495202 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base B24 mock treatment 532690.0 -9730.0 -0.08 504360.0 -37300.0 -0.32 -0.1593 -0.3497 458350.0 42891.494565217 0.2608366064319 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C01 mock treatment 495250.0 -47200.0 -0.4 531590.0 -10100.0 -0.09 -0.2197 -0.3889 374370.0 -41088.505434783 -0.24987206507042 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C02 mock treatment 483520.0 -58900.0 -0.5 505280.0 -36400.0 -0.31 -0.0855 -0.1118 446110.0 30651.494565217 0.186401334472048 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C03 mock treatment 523530.0 -18900.0 -0.16 551400.0 9710.0 0.08 0.3988 0.5867 462580.0 47121.494565217 0.286560560712143 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C04 mock treatment 526790.0 -15600.0 -0.13 479800.0 -61900.0 -0.52 0.09 0.1093 463150.0 47691.494565217 0.290026909161254 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C05 mock treatment 524640.0 -17800.0 -0.15 528290.0 -13400.0 -0.11 0.1724 0.3646 470740.0 55281.494565217 0.336184075352045 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C06 mock treatment 531010.0 -11400.0 -0.1 513320.0 -28400.0 -0.24 -0.0197 -0.0523 460350.0 44891.494565217 0.272999232569131 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C07 mock treatment 491950.0 -50500.0 -0.43 520010.0 -21700.0 -0.18 0.0186 0.0268 442600.0 27141.494565217 0.165055925601208 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C08 mock treatment 513620.0 -28800.0 -0.25 402410.0 -139000.0 -1.18 -0.5341 -0.4314 431760.0 16301.494565217 0.0991344919374169 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C09 mock treatment 529930.0 -12500.0 -0.11 524560.0 -17100.0 -0.15 0.1211 0.3077 458950.0 43491.494565217 0.264485394273069 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C10 mock treatment 479920.0 -62500.0 -0.53 502830.0 -38900.0 -0.33 -0.3697 -0.5773 437840.0 22381.494565217 0.136108875394598 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C11 mock treatment 526280.0 -16100.0 -0.14 521300.0 -20400.0 -0.17 0.0826 0.1867 433160.0 17701.494565217 0.107648330233478 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C12 mock treatment 533290.0 -9130.0 -0.08 510080.0 -31600.0 -0.27 0.0489 0.1105 435540.0 20081.494565217 0.122121855336783 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C13 mock treatment 540900.0 -1520.0 -0.01 503330.0 -38400.0 -0.33 -0.3882 -0.7418 348260.0 -67198.505434783 -0.408655149291968 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C14 mock treatment 548390.0 5970.0 0.05 541480.0 -206.0 0.0 -0.2539 -0.3754 306010.0 -109448.505434783 -0.665590626440968 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C15 mock treatment 514670.0 -27800.0 -0.24 524360.0 -17300.0 -0.15 -0.2582 -0.6695 433560.0 18101.494565217 0.110080855460925 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C16 mock treatment 513380.0 -29000.0 -0.25 486440.0 -55200.0 -0.47 -0.1676 -0.2816 450640.0 35181.494565217 0.213949682672875 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C17 mock treatment 515200.0 -27200.0 -0.23 517290.0 -24400.0 -0.21 -0.3212 -0.8919 385710.0 -29748.505434783 -0.180909974872322 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C18 mock treatment 473840.0 -68600.0 -0.58 512090.0 -29600.0 -0.25 -0.3238 -0.4978 436180.0 20721.494565217 0.126013895700697 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C19 mock treatment 515850.0 -26600.0 -0.23 470040.0 -71600.0 -0.61 -0.3946 -0.5308 376980.0 -38478.505434783 -0.233999837961334 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C20 mock treatment 553460.0 11000.0 0.09 533370.0 -8320.0 -0.07 0.1611 0.6156 451680.0 36221.494565217 0.220274248264235 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C21 mock treatment 551280.0 8860.0 0.08 506280.0 -35400.0 -0.3 -0.0228 -0.0667 422150.0 6691.494565217 0.040693073348023 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C22 mock treatment 493780.0 -48600.0 -0.41 512160.0 -29500.0 -0.25 -0.4012 -0.8031 395060.0 -20398.505434783 -0.124049697680768 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C23 mock treatment 521780.0 -20600.0 -0.18 503680.0 -38000.0 -0.32 -0.4193 -0.7642 425720.0 10261.494565217 0.0624033610029799 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base C24 mock treatment 494850.0 -47600.0 -0.4 487320.0 -54400.0 -0.46 -0.2893 -0.4362 456320.0 40861.494565217 0.248491540902611 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D01 mock treatment 592210.0 49800.0 0.42 481660.0 -60000.0 -0.51 0.3342 0.3915 468640.0 53181.494565217 0.323413317907952 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D02 mock treatment 573300.0 30900.0 0.26 533830.0 -7860.0 -0.07 0.4 0.7751 453190.0 37731.494565217 0.229457030997845 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D03 mock treatment 552580.0 10200.0 0.09 487680.0 -54000.0 -0.46 0.2169 0.287 461820.0 46361.494565217 0.281938762779995 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D04 mock treatment 577200.0 34800.0 0.3 588090.0 46400.0 0.39 0.8619 0.9745 508580.0 93121.494565217 0.566300961868451 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D05 mock treatment 572670.0 30200.0 0.26 503720.0 -38000.0 -0.32 0.0893 0.1999 434610.0 19151.494565217 0.116466234182971 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D06 mock treatment 549090.0 6670.0 0.06 549290.0 7600.0 0.06 0.0537 0.0873 485160.0 69701.494565217 0.423876609801479 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D07 mock treatment 587720.0 45300.0 0.39 587140.0 45500.0 0.39 0.307 0.5026 373230.0 -42228.505434783 -0.256804761968642 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D08 mock treatment 547770.0 5350.0 0.05 551160.0 9470.0 0.08 0.2644 0.4038 380890.0 -34568.505434783 -0.210221903863048 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D09 mock treatment 450240.0 -92200.0 -0.78 567270.0 25600.0 0.22 0.1571 0.1531 481340.0 65881.494565217 0.400645993879368 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D10 mock treatment 489920.0 -52500.0 -0.45 556130.0 14400.0 0.12 -0.0066 -0.0117 414600.0 -858.505434783001 -0.0052208403200232 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D11 mock treatment 569610.0 27200.0 0.23 592850.0 51200.0 0.43 0.1235 0.1425 456570.0 41111.494565217 0.250011869169765 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D12 mock treatment 627450.0 85000.0 0.72 557460.0 15800.0 0.13 0.7883 0.8406 507400.0 91941.494565217 0.559125012447485 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D13 mock treatment 569440.0 27000.0 0.23 531440.0 -10200.0 -0.09 0.2131 0.6544 447410.0 31951.494565217 0.194307041461248 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D14 mock treatment 554880.0 12500.0 0.11 548730.0 7040.0 0.06 -0.0259 -0.0585 443750.0 28291.494565217 0.172049435630115 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D15 mock treatment 580720.0 38300.0 0.33 522530.0 -19200.0 -0.16 0.4891 0.6943 461780.0 46321.494565217 0.281695510257251 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D16 mock treatment 538430.0 -3990.0 -0.03 585860.0 44200.0 0.37 0.1219 0.3105 417790.0 2331.494565217 0.0141785483688599 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D17 mock treatment 532560.0 -9860.0 -0.08 541980.0 294.0 0.0 0.1676 0.2994 504210.0 88751.494565217 0.539725623758602 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D18 mock treatment 470020.0 -72400.0 -0.62 567740.0 26100.0 0.22 0.1251 0.1543 485330.0 69871.494565217 0.424910433023143 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D19 mock treatment 527470.0 -15000.0 -0.13 539110.0 -2580.0 -0.02 -0.0124 -0.0612 440810.0 25351.494565217 0.154170375208386 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D20 mock treatment 568400.0 26000.0 0.22 540990.0 -696.0 -0.01 0.4228 0.8495 466190.0 50731.494565217 0.308514100889845 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D21 mock treatment 580830.0 38400.0 0.33 473820.0 -67900.0 -0.58 -0.0762 -0.1142 418660.0 3201.494565217 0.0194692907385553 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D22 mock treatment 479640.0 -62800.0 -0.53 549380.0 7690.0 0.07 -0.3502 -0.5177 440110.0 24651.494565217 0.149913456060355 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D23 mock treatment 519090.0 -23300.0 -0.2 526510.0 -15200.0 -0.13 -0.2552 -0.5313 446620.0 31161.494565217 0.189502804137042 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base D24 mock treatment 495520.0 -46900.0 -0.4 511400.0 -30300.0 -0.26 -0.4085 -0.5492 467480.0 52021.494565217 0.316358994748359 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E01 mock treatment 569120.0 26700.0 0.23 503740.0 -37900.0 -0.32 0.3783 0.5165 469500.0 54041.494565217 0.328643247146962 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E02 mock treatment 420900.0 -122000.0 -1.03 534620.0 -7070.0 -0.06 -0.9179 -0.5668 223160.0 -192298.505434783 -1.16942741417575 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E03 mock treatment 559680.0 17300.0 0.15 452400.0 -89300.0 -0.76 0.2104 0.1979 506750.0 91291.494565217 0.555172158952885 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E04 mock treatment 644690.0 102000.0 0.87 607740.0 66100.0 0.56 0.7703 0.641 354080.0 -61378.505434783 -0.373261907232627 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E05 mock treatment 570040.0 27600.0 0.23 582020.0 40300.0 0.34 0.7639 0.9634 501470.0 86011.494565217 0.523062825950596 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E06 mock treatment 576160.0 33700.0 0.29 566450.0 24800.0 0.21 0.7897 0.9352 507620.0 92161.494565217 0.56046290132258 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E07 mock treatment 506790.0 -35600.0 -0.3 608690.0 67000.0 0.57 -0.3201 -0.2496 235720.0 -179738.505434783 -1.09304612203394 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E08 mock treatment 580910.0 38500.0 0.33 550500.0 8810.0 0.07 0.334 0.752 463110.0 47651.494565217 0.289783656638509 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E09 mock treatment 562080.0 19700.0 0.17 572750.0 31100.0 0.26 0.6453 0.8181 440360.0 24901.494565217 0.151433784327509 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E10 mock treatment 549780.0 7360.0 0.06 525700.0 -16000.0 -0.14 0.3994 0.6174 472340.0 56881.494565217 0.345914176261829 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E11 mock treatment 523120.0 -19300.0 -0.16 557490.0 15800.0 0.13 0.533 0.6549 520570.0 105111.494565217 0.63921590556115 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E12 mock treatment 539910.0 -2510.0 -0.02 510040.0 -31600.0 -0.27 0.5005 0.5259 523300.0 107841.494565217 0.65581789023847 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E13 mock treatment 584990.0 42600.0 0.36 597290.0 55600.0 0.47 0.8963 0.9891 504650.0 89191.494565217 0.542401401508793 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E14 mock treatment 565280.0 22900.0 0.19 582880.0 41200.0 0.35 0.8933 0.9247 521660.0 106201.494565217 0.64584453680594 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E15 mock treatment 588320.0 45900.0 0.39 551060.0 9370.0 0.08 0.744 0.9037 495810.0 80351.494565217 0.488642593982233 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E16 mock treatment 540000.0 -2420.0 -0.02 602560.0 60900.0 0.52 -0.1987 -0.1804 256070.0 -159388.505434783 -0.969291401087621 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E17 mock treatment 581170.0 38700.0 0.33 533000.0 -8690.0 -0.07 -0.0556 -0.0821 446470.0 31011.494565217 0.188590607176749 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E18 mock treatment 572400.0 30000.0 0.26 606410.0 64700.0 0.55 0.215 0.2669 438270.0 22811.494565217 0.138723840014103 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E19 mock treatment 598850.0 56400.0 0.48 540820.0 -866.0 -0.01 0.6498 0.8544 474450.0 58991.494565217 0.358745746836608 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E20 mock treatment 572350.0 29900.0 0.25 520480.0 -21200.0 -0.18 0.3669 0.6442 458020.0 42561.494565217 0.258829773119257 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E21 mock treatment 576800.0 34400.0 0.29 553670.0 12000.0 0.1 -0.8944 -0.5642 257640.0 -157818.505434783 -0.959743739569895 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E22 mock treatment 490080.0 -52300.0 -0.45 562320.0 20600.0 0.18 0.1216 0.1947 477550.0 62091.494565217 0.377597817349316 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E23 mock treatment 514310.0 -28100.0 -0.24 529440.0 -12200.0 -0.1 -0.1738 -0.3146 471710.0 56251.494565217 0.342082949028602 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base E24 mock treatment 500760.0 -41700.0 -0.35 521800.0 -19900.0 -0.17 -0.4572 -0.4594 484640.0 69181.494565217 0.420714327005799 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F01 mock treatment 532860.0 -9560.0 -0.08 474880.0 -66800.0 -0.57 -0.3632 -0.4903 463290.0 47831.494565217 0.29087829299086 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F02 mock treatment 557170.0 14700.0 0.13 570490.0 28800.0 0.24 0.7063 0.8658 476160.0 60701.494565217 0.36914479218394 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F03 mock treatment 335930.0 -206000.0 -1.76 530100.0 -11600.0 -0.1 -0.5222 -0.2819 472440.0 56981.494565217 0.346522307568691 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F04 mock treatment 599430.0 57000.0 0.48 530020.0 -11700.0 -0.1 0.5894 0.7343 514560.0 99101.494565217 0.602667214018771 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F05 mock treatment 578620.0 36200.0 0.31 526500.0 -15200.0 -0.13 -0.0436 -0.084 434180.0 18721.494565217 0.113851269563466 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F06 mock treatment 573920.0 31500.0 0.27 568480.0 26800.0 0.23 -0.9079 -0.4968 139560.0 -275898.505434783 -1.677825186712 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F07 mock treatment 496350.0 -46100.0 -0.39 565020.0 23300.0 0.2 -0.0888 -0.1198 486300.0 70841.494565217 0.4308093066997 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F08 mock treatment 496450.0 -46000.0 -0.39 555870.0 14200.0 0.12 0.3409 0.431 501510.0 86051.494565217 0.52330607847334 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F09 mock treatment 587680.0 45300.0 0.39 588870.0 47200.0 0.4 0.3168 0.5194 429520.0 14061.494565217 0.0855123506637184 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F10 mock treatment 586990.0 44600.0 0.38 545290.0 3600.0 0.03 0.4072 0.5749 387740.0 -27718.505434783 -0.168564909343033 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F11 mock treatment 544690.0 2270.0 0.02 400380.0 -141000.0 -1.2 -0.6263 -0.5175 391080.0 -24378.505434783 -0.148253323693857 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F12 mock treatment 525720.0 -16700.0 -0.14 515330.0 -26400.0 -0.22 0.0758 0.1672 453280.0 37821.494565217 0.23000434917402 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F13 mock treatment 564980.0 22600.0 0.19 649190.0 108000.0 0.91 1.0208 0.8765 518120.0 102661.494565217 0.624316688543042 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F14 mock treatment 543940.0 1520.0 0.01 571620.0 29900.0 0.25 -0.3458 -0.4493 367090.0 -48368.505434783 -0.29414402420994 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F15 mock treatment 544810.0 2390.0 0.02 550100.0 8410.0 0.07 0.4224 0.739 499940.0 84481.494565217 0.513758416955614 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F16 mock treatment 502960.0 -39500.0 -0.34 468190.0 -73500.0 -0.62 -0.4856 -0.6077 457520.0 42061.494565217 0.255789116584949 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F17 mock treatment 559470.0 17000.0 0.15 546030.0 4340.0 0.04 0.4325 0.7795 498160.0 82701.494565217 0.502933679693479 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F18 mock treatment 624180.0 81800.0 0.7 584900.0 43200.0 0.37 0.4011 0.341 493540.0 78081.494565217 0.474838013316476 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F19 mock treatment 490100.0 -52300.0 -0.45 572120.0 30400.0 0.26 0.1292 0.1756 403080.0 -12378.505434783 -0.0752775668704725 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F20 mock treatment 613780.0 71400.0 0.61 605120.0 63400.0 0.54 0.7437 0.8093 402030.0 -13428.505434783 -0.0816629455925186 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F21 mock treatment 528770.0 -13700.0 -0.12 564610.0 22900.0 0.19 -0.603 -0.6329 330560.0 -84898.505434783 -0.516294390606461 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F22 mock treatment 538850.0 -3570.0 -0.03 440090.0 -102000.0 -0.86 -0.3137 -0.3542 428210.0 12751.494565217 0.0775458305438322 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F23 mock treatment 537120.0 -5300.0 -0.05 492960.0 -48700.0 -0.41 0.0197 0.0356 445120.0 29661.494565217 0.180380834534118 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base F24 mock treatment 509930.0 -32500.0 -0.28 513600.0 -28100.0 -0.24 0.026 0.0439 434610.0 19151.494565217 0.116466234182971 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G01 mock treatment 529440.0 -13000.0 -0.11 531080.0 -10600.0 -0.09 0.3811 0.5376 478640.0 63181.494565217 0.384226448594106 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G02 mock treatment 520270.0 -22200.0 -0.19 565660.0 24000.0 0.2 0.275 0.3942 399410.0 -16048.505434783 -0.097595985832291 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G03 mock treatment 485300.0 -57100.0 -0.49 563250.0 21600.0 0.18 0.4167 0.4352 513510.0 98051.494565217 0.596281835296725 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G04 mock treatment 585950.0 43500.0 0.37 552820.0 11100.0 0.09 0.0369 0.0411 472110.0 56651.494565217 0.344515474256048 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G05 mock treatment 614040.0 71600.0 0.61 493380.0 -48300.0 -0.41 -0.1577 -0.1431 458800.0 43341.494565217 0.263573197312777 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G06 mock treatment 533130.0 -9290.0 -0.08 544450.0 2760.0 0.02 0.0195 0.0208 531850.0 116391.494565217 0.707813116975131 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G07 mock treatment 559000.0 16600.0 0.14 552350.0 10700.0 0.09 -0.1259 -0.1174 259200.0 -156258.505434783 -0.950256891182855 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G08 mock treatment 593400.0 51000.0 0.43 602400.0 60700.0 0.52 0.8709 0.9903 471940.0 56481.494565217 0.343481651034383 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G09 mock treatment 532730.0 -9690.0 -0.08 552600.0 10900.0 0.09 -0.2958 -0.2427 233990.0 -181468.505434783 -1.10356679364265 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G10 mock treatment 525520.0 -16900.0 -0.14 542240.0 554.0 0.0 0.2873 0.5057 448820.0 33361.494565217 0.202881692887995 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G11 mock treatment 486120.0 -56300.0 -0.48 617610.0 75900.0 0.64 0.3538 0.3688 501780.0 86321.494565217 0.524948033001866 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G12 mock treatment 438810.0 -104000.0 -0.88 453340.0 -88300.0 -0.75 -0.2893 -0.21 493410.0 77951.494565217 0.474047442617556 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G13 mock treatment 595250.0 52800.0 0.45 631520.0 89800.0 0.76 1.096 0.9748 499260.0 83801.494565217 0.509623124068956 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G14 mock treatment 602430.0 60000.0 0.51 630120.0 88400.0 0.75 0.9144 0.9171 473400.0 57941.494565217 0.352360368114562 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G15 mock treatment 549460.0 7040.0 0.06 596330.0 54600.0 0.46 0.1409 0.2059 450260.0 34801.494565217 0.211638783706802 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G16 mock treatment 558400.0 16000.0 0.14 577600.0 35900.0 0.3 -0.284 -0.3568 319000.0 -96458.505434783 -0.586594369679654 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G17 mock treatment 562760.0 20300.0 0.17 541990.0 304.0 0.0 0.4025 0.8338 475420.0 59961.494565217 0.364644620513165 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G18 mock treatment 592670.0 50200.0 0.43 562080.0 20400.0 0.17 -0.0641 -0.0724 419880.0 4421.494565217 0.0268884926822661 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G19 mock treatment 601570.0 59100.0 0.5 569200.0 27500.0 0.23 0.564 0.822 413440.0 -2018.505434783 -0.0122751634796171 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G20 mock treatment 599120.0 56700.0 0.48 533940.0 -7750.0 -0.07 -0.2496 -0.2966 366590.0 -48868.505434783 -0.297184680744248 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G21 mock treatment 621600.0 79200.0 0.67 518760.0 -22900.0 -0.19 0.2607 0.2966 357400.0 -58058.505434783 -0.353071947844823 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G22 mock treatment 507370.0 -35100.0 -0.3 372400.0 -169000.0 -1.44 -1.4955 -0.8496 266000.0 -149458.505434783 -0.90890396231627 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G23 mock treatment 511920.0 -30500.0 -0.26 532130.0 -9560.0 -0.08 -0.4479 -0.841 397230.0 -18228.505434783 -0.110853248321873 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base G24 mock treatment 530960.0 -11500.0 -0.1 475890.0 -65800.0 -0.56 -0.8865 -0.694 227240.0 -188218.505434783 -1.1446156568558 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H01 mock treatment 343380.0 -199000.0 -1.69 587580.0 45900.0 0.39 -0.163 -0.0855 453180.0 37721.494565217 0.229396217867159 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H02 mock treatment 595360.0 52900.0 0.45 576080.0 34400.0 0.29 0.5393 0.5688 356540.0 -58918.505434783 -0.358301877083833 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H03 mock treatment 545450.0 3030.0 0.03 532800.0 -8890.0 -0.08 -0.1356 -0.5061 373720.0 -41738.505434783 -0.25382491856502 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H04 mock treatment 539010.0 -3410.0 -0.03 548900.0 7210.0 0.06 -0.3917 -0.2667 191520.0 -223938.505434783 -1.36184015966674 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H05 mock treatment 638360.0 95900.0 0.82 587520.0 45800.0 0.39 1.2137 0.9518 544820.0 129361.494565217 0.786687747475073 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H06 mock treatment 630880.0 88500.0 0.75 472520.0 -69200.0 -0.59 -0.0813 -0.061 493140.0 77681.494565217 0.472405488089029 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H07 mock treatment 607360.0 64900.0 0.55 493340.0 -48300.0 -0.41 -0.0432 -0.0479 461920.0 46461.494565217 0.282546894086857 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H08 mock treatment 588560.0 46100.0 0.39 571220.0 29500.0 0.25 -0.0208 -0.0204 448110.0 32651.494565217 0.198563960609278 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H09 mock treatment 600660.0 58200.0 0.5 647780.0 106000.0 0.9 0.5496 0.4223 301450.0 -114008.505434783 -0.693321414033855 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H10 mock treatment 610690.0 68300.0 0.58 577970.0 36300.0 0.31 0.9376 0.9767 490400.0 74941.494565217 0.455742690281023 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H11 mock treatment 503680.0 -38700.0 -0.33 659110.0 117000.0 1.0 -0.2117 -0.1605 350500.0 -64958.505434783 -0.39503300801827 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H12 mock treatment 453210.0 -89200.0 -0.76 501210.0 -40500.0 -0.34 -1.5228 -0.9372 227680.0 -187778.505434783 -1.14193987910561 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H13 mock treatment 533920.0 -8500.0 -0.07 500990.0 -40700.0 -0.35 -0.8169 -0.7522 380760.0 -34698.505434783 -0.211012474561968 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H14 mock treatment 600770.0 58300.0 0.5 665550.0 124000.0 1.05 -0.0864 -0.0504 312590.0 -102868.505434783 -0.625575586449479 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H15 mock treatment 514950.0 -27500.0 -0.23 494930.0 -46800.0 -0.4 -0.3788 -0.7581 385000.0 -30458.505434783 -0.185227707151039 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H16 mock treatment 558470.0 16000.0 0.14 368290.0 -173000.0 -1.47 -0.5441 -0.3526 483380.0 67921.494565217 0.413051872539343 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H17 mock treatment 554720.0 12300.0 0.1 596660.0 55000.0 0.47 -0.0506 -0.0349 211040.0 -204418.505434783 -1.24313292856737 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H18 mock treatment 602330.0 59900.0 0.51 613240.0 71600.0 0.61 0.9211 0.9432 446080.0 30621.494565217 0.186218895079989 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H19 mock treatment 630740.0 88300.0 0.75 626660.0 85000.0 0.72 0.8706 0.8177 451040.0 35581.494565217 0.216382207900322 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H20 mock treatment 613840.0 71400.0 0.61 602660.0 61000.0 0.52 0.7672 0.8373 489240.0 73781.494565217 0.448688367121429 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H21 mock treatment 474350.0 -68100.0 -0.58 588170.0 46500.0 0.39 -0.4425 -0.3514 250670.0 -164788.505434783 -1.00213049165814 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H22 mock treatment 478580.0 -63800.0 -0.54 486190.0 -55500.0 -0.47 -0.9574 -0.7445 440820.0 25361.494565217 0.154231188339072 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H23 mock treatment 533500.0 -8920.0 -0.08 570340.0 28700.0 0.24 -1.0178 -0.6323 197530.0 -217928.505434783 -1.32529146812437 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base H24 mock treatment 500530.0 -41900.0 -0.36 443880.0 -97800.0 -0.83 -1.2624 -0.949 277400.0 -138058.505434783 -0.839576993334055 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I01 mock treatment 622980.0 80600.0 0.69 523240.0 -18400.0 -0.16 0.7671 0.745 469440.0 53981.494565217 0.328278368362845 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I02 mock treatment 603120.0 60700.0 0.52 536930.0 -4760.0 -0.04 -0.0445 -0.0449 455650.0 40191.494565217 0.244417061146639 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I03 mock treatment 523890.0 -18500.0 -0.16 590630.0 48900.0 0.42 -0.3295 -0.1746 140520.0 -274938.505434783 -1.67198712616613 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I04 mock treatment 474830.0 -67600.0 -0.58 569400.0 27700.0 0.24 -0.4903 -0.3473 225120.0 -190338.505434783 -1.15750804056127 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I05 mock treatment 431700.0 -111000.0 -0.94 562530.0 20800.0 0.18 0.052 0.0454 471950.0 56491.494565217 0.343542464165069 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I06 mock treatment 548760.0 6340.0 0.05 510160.0 -31500.0 -0.27 -0.4941 -0.6102 413410.0 -2048.505434783 -0.0124576028716755 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I07 mock treatment 590650.0 48200.0 0.41 615050.0 73400.0 0.62 0.8726 0.9636 485950.0 70491.494565217 0.428680847125685 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I08 mock treatment 584700.0 42300.0 0.36 600240.0 58600.0 0.5 0.5465 0.752 393950.0 -21508.505434783 -0.130799955186931 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I09 mock treatment 633360.0 90900.0 0.77 597800.0 56100.0 0.48 0.9861 0.9448 468280.0 52821.494565217 0.321224045203251 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I10 mock treatment 604420.0 62000.0 0.53 595700.0 54000.0 0.46 0.4353 0.5481 363140.0 -52318.505434783 -0.318165210830971 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I11 mock treatment 601920.0 59500.0 0.51 564280.0 22600.0 0.19 0.128 0.09 230610.0 -184848.505434783 -1.12412163181457 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I12 mock treatment 539570.0 -2850.0 -0.02 622580.0 80900.0 0.69 -0.7467 -0.4239 173600.0 -241858.505434783 -1.47081728985633 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I13 mock treatment 593960.0 51500.0 0.44 585150.0 43500.0 0.37 0.5125 0.8357 415280.0 -178.505434783001 -0.00108554743336474 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I14 mock treatment 660100.0 118000.0 1.0 654310.0 113000.0 0.96 1.079 0.7543 470720.0 55261.494565217 0.336062449090672 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I15 mock treatment 646100.0 104000.0 0.88 642830.0 101000.0 0.86 1.1266 0.855 492610.0 77151.494565217 0.469182392162663 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I16 mock treatment 557520.0 15100.0 0.13 588010.0 46300.0 0.39 0.6083 0.923 489760.0 74301.494565217 0.451850649917109 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I17 mock treatment 613440.0 71000.0 0.6 574280.0 32600.0 0.28 0.1682 0.1544 460530.0 45071.494565217 0.274093868921482 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I18 mock treatment 571620.0 29200.0 0.25 625480.0 83800.0 0.71 1.0885 0.9445 499320.0 83861.494565217 0.509988002853073 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I19 mock treatment 521570.0 -20900.0 -0.18 617830.0 76100.0 0.65 0.4672 0.5501 406670.0 -8788.505434783 -0.0534456529541432 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I20 mock treatment 643800.0 101000.0 0.86 574050.0 32400.0 0.27 0.8828 0.8529 494280.0 78821.494565217 0.479338184987251 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I21 mock treatment 584580.0 42200.0 0.36 573670.0 32000.0 0.27 0.174 0.2551 337350.0 -78108.505434783 -0.475002274870562 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I22 mock treatment 289230.0 -253000.0 -2.15 513150.0 -28500.0 -0.24 -1.8247 -0.7173 427970.0 12511.494565217 0.0760863154073645 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I23 mock treatment 548170.0 5750.0 0.05 550240.0 8550.0 0.07 -0.1201 -0.1222 275860.0 -139598.505434783 -0.848942215459722 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base I24 mock treatment 458920.0 -83500.0 -0.71 415900.0 -126000.0 -1.07 -1.3258 -0.9063 304160.0 -111298.505434783 -0.676841055617907 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J01 mock treatment 535170.0 -7250.0 -0.06 486660.0 -55000.0 -0.47 -0.8218 -0.5243 176100.0 -239358.505434783 -1.45561400718479 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J02 mock treatment 402970.0 -139000.0 -1.19 516890.0 -24800.0 -0.21 -1.1792 -0.5962 172030.0 -243428.505434783 -1.48036495137406 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J03 mock treatment 493120.0 -49300.0 -0.42 599060.0 57400.0 0.49 -0.2812 -0.2109 238150.0 -177308.505434783 -1.07826853127721 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J04 mock treatment 516740.0 -25700.0 -0.22 548870.0 7180.0 0.06 -0.4335 -0.3111 208260.0 -207198.505434783 -1.26003897889812 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J05 mock treatment 509690.0 -32700.0 -0.28 509840.0 -31800.0 -0.27 -0.2516 -0.5132 453840.0 38381.494565217 0.233409884492445 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J06 mock treatment 585600.0 43200.0 0.37 462210.0 -79500.0 -0.67 -0.2753 -0.3192 436520.0 21061.494565217 0.128081542144026 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J07 mock treatment 402400.0 -140000.0 -1.19 509030.0 -32700.0 -0.28 -1.1924 -0.7497 431200.0 15741.494565217 0.0957289566189923 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J08 mock treatment 574460.0 32000.0 0.27 597890.0 56200.0 0.48 0.9556 0.9628 500220.0 84761.494565217 0.515461184614826 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J09 mock treatment 571780.0 29400.0 0.25 584290.0 42600.0 0.36 0.4624 0.8811 462440.0 46981.494565217 0.285709176882537 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J10 mock treatment 581370.0 38900.0 0.33 657440.0 116000.0 0.98 0.7585 0.7225 422130.0 6671.494565217 0.0405714470866507 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J11 mock treatment 621460.0 79000.0 0.67 617600.0 75900.0 0.64 1.0328 0.95 498650.0 83191.494565217 0.5059135230971 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J12 mock treatment 567540.0 25100.0 0.21 572750.0 31100.0 0.26 -0.0354 -0.0365 466020.0 50561.494565217 0.30748027766818 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J13 mock treatment 499600.0 -42800.0 -0.36 628670.0 87000.0 0.74 0.1213 0.1392 436250.0 20791.494565217 0.1264395876155 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J14 mock treatment 502580.0 -39800.0 -0.34 617330.0 75600.0 0.64 0.5037 0.5096 421120.0 5661.494565217 0.0344293208873491 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J15 mock treatment 582050.0 39600.0 0.34 596280.0 54600.0 0.46 0.7787 0.9907 484070.0 68611.494565217 0.417247978556688 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J16 mock treatment 597970.0 55500.0 0.47 584480.0 42800.0 0.36 0.7542 0.9792 483400.0 67941.494565217 0.413173498800716 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J17 mock treatment 603220.0 60800.0 0.52 516600.0 -25100.0 -0.21 -0.0109 -0.0151 343090.0 -72368.505434783 -0.44009553785671 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J18 mock treatment 583630.0 41200.0 0.35 556040.0 14400.0 0.12 -0.3696 -0.3919 300320.0 -115138.505434783 -0.70019329780139 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J19 mock treatment 610040.0 67600.0 0.58 521990.0 -19700.0 -0.17 -0.3986 -0.3701 348100.0 -67358.505434783 -0.409628159382947 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J20 mock treatment 534800.0 -7620.0 -0.06 565830.0 24100.0 0.2 0.394 0.7535 453440.0 37981.494565217 0.230977359264999 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J21 mock treatment 529120.0 -13300.0 -0.11 542680.0 994.0 0.01 -0.1577 -0.8411 399200.0 -16258.505434783 -0.0988730615767002 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J22 mock treatment 448030.0 -94400.0 -0.8 515070.0 -26600.0 -0.23 -0.9937 -0.7369 431330.0 15871.494565217 0.0965195273179123 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J23 mock treatment 501240.0 -41200.0 -0.35 528220.0 -13500.0 -0.11 -0.2928 -0.6143 439220.0 23761.494565217 0.144501087429288 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base J24 mock treatment 505120.0 -37300.0 -0.32 390780.0 -151000.0 -1.28 -0.4813 -0.3386 434960.0 19501.494565217 0.118594693756986 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K01 mock treatment 593000.0 50600.0 0.43 573830.0 32100.0 0.27 1.1561 0.9259 539680.0 124221.494565217 0.75542979830239 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K02 mock treatment 627420.0 85000.0 0.72 485330.0 -56400.0 -0.48 0.6061 0.5314 461730.0 46271.494565217 0.28139144460382 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K03 mock treatment 603440.0 61000.0 0.52 511440.0 -30200.0 -0.26 0.9723 0.7345 559370.0 143911.494565217 0.875170852623427 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K04 mock treatment 608290.0 65900.0 0.56 455210.0 -86500.0 -0.73 0.3717 0.3059 438240.0 22781.494565217 0.138541400622045 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K05 mock treatment 634960.0 92500.0 0.79 633560.0 91900.0 0.78 0.7808 0.6024 493280.0 77821.494565217 0.473256871918636 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K06 mock treatment 475750.0 -66700.0 -0.57 563150.0 21500.0 0.18 -1.3496 -0.7301 153120.0 -262338.505434783 -1.59536258150158 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K07 mock treatment 623550.0 81100.0 0.69 401370.0 -140000.0 -1.19 0.2276 0.1485 491370.0 75911.494565217 0.46164156395758 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K08 mock treatment 627730.0 85300.0 0.73 603070.0 61400.0 0.52 0.6355 0.6503 371420.0 -44038.505434783 -0.267811938622836 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K09 mock treatment 613710.0 71300.0 0.61 593000.0 51300.0 0.44 0.9024 0.9698 462880.0 47421.494565217 0.288384954632728 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K10 mock treatment 585060.0 42600.0 0.36 662890.0 121000.0 1.03 0.1609 0.1186 360800.0 -54658.505434783 -0.332395483411531 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K11 mock treatment 554080.0 11700.0 0.1 500290.0 -41400.0 -0.35 -0.0334 -0.0714 461200.0 45741.494565217 0.278168348677454 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K12 mock treatment 539360.0 -3060.0 -0.03 546280.0 4590.0 0.04 -0.2088 -0.4638 418240.0 2781.494565217 0.0169151392497368 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K13 mock treatment 604570.0 62100.0 0.53 597630.0 55900.0 0.47 0.1886 0.2229 349730.0 -65728.505434783 -0.399715619081103 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K14 mock treatment 589030.0 46600.0 0.4 570990.0 29300.0 0.25 0.8266 0.9384 524030.0 108571.494565217 0.660257248778559 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K15 mock treatment 546170.0 3750.0 0.03 657330.0 116000.0 0.98 0.1112 0.0953 316480.0 -98978.505434783 -0.601919278612565 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K16 mock treatment 611050.0 68600.0 0.58 648540.0 107000.0 0.91 1.3711 0.9827 521350.0 105891.494565217 0.64395932975467 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K17 mock treatment 624610.0 82200.0 0.7 609080.0 67400.0 0.57 1.0253 0.8998 430400.0 14941.494565217 0.0908639061641 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K18 mock treatment 674720.0 132000.0 1.13 676350.0 135000.0 1.14 1.1335 0.5956 534580.0 119121.494565217 0.724415101652451 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K19 mock treatment 562970.0 20500.0 0.17 618080.0 76400.0 0.65 0.8081 0.8989 504810.0 89351.494565217 0.543374411599771 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K20 mock treatment 649770.0 107000.0 0.91 677890.0 136000.0 1.16 1.5641 0.9341 471000.0 55541.494565217 0.337765216749885 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K21 mock treatment 552960.0 10500.0 0.09 603880.0 62200.0 0.53 0.9421 0.8574 479640.0 64181.494565217 0.390307761662722 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K22 mock treatment 555520.0 13100.0 0.11 559370.0 17700.0 0.15 0.5213 0.8703 463770.0 48311.494565217 0.293797323263795 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K23 mock treatment 541870.0 -552.0 0.0 552660.0 11000.0 0.09 0.3438 0.7536 481120.0 65661.494565217 0.399308105004273 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base K24 mock treatment 493920.0 -48500.0 -0.41 547110.0 5420.0 0.05 -0.2458 -0.2303 291300.0 -124158.505434783 -0.755046741680301 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L01 mock treatment 573080.0 30700.0 0.26 476720.0 -65000.0 -0.55 -0.8296 -0.6917 344810.0 -70648.505434783 -0.429635679378691 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L02 mock treatment 534020.0 -8400.0 -0.07 531150.0 -10500.0 -0.09 -0.2728 -0.706 354830.0 -60628.505434783 -0.368700922431165 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L03 mock treatment 510160.0 -32300.0 -0.27 542640.0 954.0 0.01 0.2704 0.419 467470.0 52011.494565217 0.316298181617672 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L04 mock treatment 594950.0 52500.0 0.45 566490.0 24800.0 0.21 0.7058 0.7963 418520.0 3061.494565217 0.0186179069089491 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L05 mock treatment 335520.0 -207000.0 -1.76 478100.0 -63600.0 -0.54 -1.1961 -0.5854 305060.0 -110398.505434783 -0.671367873856153 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L06 mock treatment 330240.0 -212000.0 -1.81 441640.0 -100000.0 -0.85 -1.1296 -0.5463 502370.0 86911.494565217 0.52853600771235 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L07 mock treatment 480850.0 -61600.0 -0.52 211060.0 -331000.0 -2.8 -2.0638 -0.6758 457980.0 42521.494565217 0.258586520596512 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L08 mock treatment 442370.0 -100000.0 -0.85 317240.0 -224000.0 -1.9 -1.5979 -0.6636 244040.0 -171418.505434783 -1.04244959730306 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L09 mock treatment 553510.0 11100.0 0.09 593670.0 52000.0 0.44 0.4247 0.7159 404650.0 -10808.505434783 -0.0657299053527463 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L10 mock treatment 597320.0 54900.0 0.47 646730.0 105000.0 0.89 1.2427 0.9681 506030.0 90571.494565217 0.550793613543482 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L11 mock treatment 541640.0 -782.0 -0.01 611600.0 69900.0 0.59 -0.0823 -0.09 406110.0 -9348.505434783 -0.0568511882725679 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L12 mock treatment 544070.0 1650.0 0.01 616410.0 74700.0 0.63 0.5205 0.7486 455360.0 39901.494565217 0.24265348035674 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L13 mock treatment 594570.0 52100.0 0.44 531480.0 -10200.0 -0.09 -0.0445 -0.0401 490620.0 75161.494565217 0.457080579156119 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L14 mock treatment 599210.0 56800.0 0.48 621440.0 79800.0 0.68 0.6306 0.7403 403900.0 -11558.505434783 -0.0702908901542079 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L15 mock treatment 532070.0 -10400.0 -0.09 549930.0 8240.0 0.07 -0.1462 -0.5932 404820.0 -10638.505434783 -0.0646960821310817 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L16 mock treatment 579050.0 36600.0 0.31 504760.0 -36900.0 -0.31 0.0663 0.1208 462760.0 47301.494565217 0.287655197064494 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L17 mock treatment 624700.0 82300.0 0.7 629030.0 87300.0 0.74 1.2746 0.9874 519910.0 104451.494565217 0.635202238935863 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L18 mock treatment 506150.0 -36300.0 -0.31 670910.0 129000.0 1.1 0.2416 0.1824 315880.0 -99578.505434783 -0.605568066453734 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L19 mock treatment 592230.0 49800.0 0.42 598360.0 56700.0 0.48 0.5639 0.6856 490880.0 75421.494565217 0.458661720553959 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L20 mock treatment 561450.0 19000.0 0.16 519090.0 -22600.0 -0.19 0.5301 0.6504 515000.0 99541.494565217 0.605342991768962 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L21 mock treatment 608540.0 66100.0 0.56 619440.0 77800.0 0.66 0.2318 0.163 468400.0 52941.494565217 0.321953802771485 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L22 mock treatment 583160.0 40700.0 0.35 551900.0 10200.0 0.09 0.3709 0.5484 502610.0 87151.494565217 0.529995522848817 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L23 mock treatment 552420.0 10000.0 0.09 570470.0 28800.0 0.24 0.3973 0.9462 457700.0 42241.494565217 0.2568837529373 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base L24 mock treatment 501280.0 -41100.0 -0.35 508650.0 -33000.0 -0.28 -0.3637 -0.7681 391640.0 -23818.505434783 -0.144847788375433 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M01 mock treatment 339370.0 -203000.0 -1.73 559150.0 17500.0 0.15 -1.3361 -0.5778 172070.0 -243388.505434783 -1.48012169885131 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M02 mock treatment 552750.0 10300.0 0.09 581550.0 39900.0 0.34 0.7305 0.8673 474080.0 58621.494565217 0.35649566100122 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M03 mock treatment 429460.0 -113000.0 -0.96 554050.0 12400.0 0.1 -0.636 -0.4298 255520.0 -159938.505434783 -0.972636123275359 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M04 mock treatment 556590.0 14200.0 0.12 482800.0 -58900.0 -0.5 -0.4472 -0.302 217280.0 -198178.505434783 -1.20518553501921 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M05 mock treatment 418720.0 -124000.0 -1.05 431380.0 -110000.0 -0.94 -1.2911 -0.6759 224700.0 -190758.505434783 -1.16006219205009 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M06 mock treatment 588280.0 45900.0 0.39 621120.0 79400.0 0.67 0.5732 0.6974 452090.0 36631.494565217 0.222767586622368 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M07 mock treatment 588690.0 46300.0 0.39 570010.0 28300.0 0.24 -0.1437 -0.1714 369490.0 -45968.505434783 -0.279548872845263 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M08 mock treatment 560250.0 17800.0 0.15 566690.0 25000.0 0.21 0.203 0.3916 366940.0 -48518.505434783 -0.295056221170233 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M09 mock treatment 567540.0 25100.0 0.21 632770.0 91100.0 0.77 0.8316 0.8775 490020.0 74561.494565217 0.453431791314949 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M10 mock treatment 586240.0 43800.0 0.37 629450.0 87800.0 0.74 0.6495 0.6956 477200.0 61741.494565217 0.3754693577753 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M11 mock treatment 581330.0 38900.0 0.33 639450.0 97800.0 0.83 0.8383 0.7824 512100.0 96641.494565217 0.587707183869977 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M12 mock treatment 510110.0 -32300.0 -0.27 627390.0 85700.0 0.73 0.3431 0.4225 415310.0 -148.505434783001 -9.03108041306274E-4 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M13 mock treatment 541160.0 -1260.0 -0.01 601810.0 60100.0 0.51 -0.3041 -0.3053 364450.0 -51008.505434783 -0.310198690711085 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M14 mock treatment 592510.0 50100.0 0.43 577470.0 35800.0 0.3 0.3006 0.5023 436960.0 21501.494565217 0.130757319894217 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M15 mock treatment 594400.0 52000.0 0.44 622850.0 81200.0 0.69 0.1268 0.0982 434240.0 18781.494565217 0.114216148347583 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M16 mock treatment 635390.0 93000.0 0.79 643430.0 102000.0 0.86 1.2496 0.9507 485360.0 69901.494565217 0.425092872415202 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M17 mock treatment 567610.0 25200.0 0.21 601950.0 60300.0 0.51 0.3364 0.4984 366560.0 -48898.505434783 -0.297367120136307 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M18 mock treatment 570650.0 28200.0 0.24 576530.0 34800.0 0.3 0.7317 0.9293 516290.0 100831.494565217 0.613187885627476 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M19 mock treatment 599860.0 57400.0 0.49 544250.0 2560.0 0.02 0.6281 0.8489 496960.0 81501.494565217 0.49563610401114 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M20 mock treatment 556720.0 14300.0 0.12 588160.0 46500.0 0.39 -0.0768 -0.0966 417220.0 1761.494565217 0.0107121999197491 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M21 mock treatment 552180.0 9760.0 0.08 543680.0 1990.0 0.02 -0.0897 -0.2454 358080.0 -57378.505434783 -0.348936654958165 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M22 mock treatment 537660.0 -4760.0 -0.04 566770.0 25100.0 0.21 -0.0308 -0.0398 480360.0 64901.494565217 0.394686307072125 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M23 mock treatment 537300.0 -5120.0 -0.04 560650.0 19000.0 0.16 0.1527 0.3081 482930.0 67471.494565217 0.410315281658466 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base M24 mock treatment 479780.0 -62600.0 -0.53 504810.0 -36900.0 -0.31 -0.2191 -0.3114 428670.0 13211.494565217 0.0803432345553953 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N01 mock treatment 504410.0 -38000.0 -0.32 569440.0 27800.0 0.24 -0.4001 -0.4045 269540.0 -145918.505434783 -0.887376114053372 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N02 mock treatment 554730.0 12300.0 0.1 512500.0 -29200.0 -0.25 0.2644 0.4654 452320.0 36861.494565217 0.224166288628149 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N03 mock treatment 584190.0 41800.0 0.36 555600.0 13900.0 0.12 0.5376 0.8534 432980.0 17521.494565217 0.106553693881128 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N04 mock treatment 514670.0 -27800.0 -0.24 532810.0 -8880.0 -0.08 0.0083 0.0146 495300.0 79841.494565217 0.485541124317239 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N05 mock treatment 562360.0 19900.0 0.17 556590.0 14900.0 0.13 0.1894 0.6091 447860.0 32401.494565217 0.197043632342125 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N06 mock treatment 572180.0 29800.0 0.25 368980.0 -173000.0 -1.47 -1.2267 -0.6945 270050.0 -145408.505434783 -0.884274644388378 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N07 mock treatment 552220.0 9800.0 0.08 575300.0 33600.0 0.29 0.2972 0.8812 434160.0 18701.494565217 0.113729643302094 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N08 mock treatment 601280.0 58900.0 0.5 600710.0 59000.0 0.5 0.5704 0.7856 412200.0 -3258.505434783 -0.0198159916847001 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N09 mock treatment 560740.0 18300.0 0.16 604440.0 62800.0 0.53 0.8853 0.929 490350.0 74891.494565217 0.455438624627592 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N10 mock treatment 605380.0 63000.0 0.54 590300.0 48600.0 0.41 0.7217 0.8648 416450.0 991.494565216999 0.00602958885691527 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N11 mock treatment 576710.0 34300.0 0.29 652640.0 111000.0 0.94 0.7321 0.6177 360270.0 -55188.505434783 -0.335618579337897 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N12 mock treatment 614810.0 72400.0 0.62 554410.0 12700.0 0.11 0.3168 0.4955 421760.0 6301.494565217 0.038321361251263 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N13 mock treatment 569500.0 27100.0 0.23 576230.0 34500.0 0.29 0.4194 0.9627 437530.0 22071.494565217 0.134223668343328 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N14 mock treatment 572270.0 29800.0 0.25 602780.0 61100.0 0.52 0.386 0.57 456640.0 41181.494565217 0.250437561084568 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N15 mock treatment 607400.0 65000.0 0.55 610400.0 68700.0 0.58 0.8139 0.8705 494100.0 78641.494565217 0.4782435486349 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N16 mock treatment 602880.0 60500.0 0.51 574830.0 33100.0 0.28 0.9073 0.9661 515330.0 99871.494565217 0.607349825081605 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N17 mock treatment 565920.0 23500.0 0.2 615810.0 74100.0 0.63 0.3714 0.558 415890.0 431.494565216999 0.00262405353849065 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N18 mock treatment 597200.0 54800.0 0.47 540600.0 -1090.0 -0.01 0.573 0.7995 500330.0 84871.494565217 0.516130129052374 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N19 mock treatment 604000.0 61600.0 0.52 540040.0 -1650.0 -0.01 0.596 0.8277 483840.0 68381.494565217 0.415849276550906 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N20 mock treatment 550770.0 8350.0 0.07 545970.0 4280.0 0.04 0.4407 0.7941 484380.0 68921.494565217 0.419133185607959 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N21 mock treatment 536530.0 -5890.0 -0.05 512540.0 -29100.0 -0.25 -0.0012 -0.0036 433000.0 17541.494565217 0.1066753201425 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N22 mock treatment 550680.0 8260.0 0.07 583280.0 41600.0 0.35 0.5166 0.9147 472400.0 56941.494565217 0.346279055045946 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N23 mock treatment 531230.0 -11200.0 -0.1 574400.0 32700.0 0.28 0.1652 0.3204 475380.0 59921.494565217 0.36440136799042 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base N24 mock treatment 510740.0 -31700.0 -0.27 508600.0 -33100.0 -0.28 -0.7974 -0.9535 335220.0 -80238.505434783 -0.487955471706713 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O01 mock treatment 485760.0 -56700.0 -0.48 464520.0 -77200.0 -0.65 -0.9583 -0.6924 237990.0 -177468.505434783 -1.07924154136819 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O02 mock treatment 486030.0 -56400.0 -0.48 537140.0 -4550.0 -0.04 -0.5428 -0.4914 263040.0 -152418.505434783 -0.926904648999372 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O03 mock treatment 477820.0 -64600.0 -0.55 536130.0 -5560.0 -0.05 -0.6006 -0.8244 390100.0 -25358.505434783 -0.1542130105011 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O04 mock treatment 521720.0 -20700.0 -0.18 481130.0 -60600.0 -0.51 -1.0224 -0.8897 265920.0 -149538.505434783 -0.909390467361759 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O05 mock treatment 360020.0 -182000.0 -1.55 421440.0 -120000.0 -1.02 -1.9403 -0.9139 255460.0 -159998.505434783 -0.973001002059476 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O06 mock treatment 497800.0 -44600.0 -0.38 472070.0 -69600.0 -0.59 -0.3134 -0.4218 444960.0 29501.494565217 0.17940782444314 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O07 mock treatment 446360.0 -96100.0 -0.82 327310.0 -214000.0 -1.82 -1.2886 -0.6459 426980.0 11521.494565217 0.0700658154694353 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O08 mock treatment 489830.0 -52600.0 -0.45 488800.0 -52900.0 -0.45 -0.7074 -0.965 377040.0 -38418.505434783 -0.233634959177217 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O09 mock treatment 490450.0 -52000.0 -0.44 488450.0 -53200.0 -0.45 -0.4037 -0.6313 413690.0 -1768.505434783 -0.0107548352124632 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O10 mock treatment 473040.0 -69400.0 -0.59 496500.0 -45200.0 -0.38 -0.3801 -0.5121 411870.0 -3588.505434783 -0.0218228249973432 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O11 mock treatment 486750.0 -55700.0 -0.47 494580.0 -47100.0 -0.4 -0.8246 -0.7309 262520.0 -152938.505434783 -0.930066931795052 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O12 mock treatment 495000.0 -47400.0 -0.4 574190.0 32500.0 0.28 -0.0474 -0.0957 409600.0 -5858.505434783 -0.0356274056631001 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O13 mock treatment 430830.0 -112000.0 -0.95 452960.0 -88700.0 -0.75 -0.8671 -0.6848 455560.0 40101.494565217 0.243869742970463 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O14 mock treatment 514180.0 -28200.0 -0.24 559170.0 17500.0 0.15 -0.0764 -0.2285 430660.0 15201.494565217 0.0924450475619399 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O15 mock treatment 520990.0 -21400.0 -0.18 526430.0 -15300.0 -0.13 -0.0208 -0.0406 388870.0 -26588.505434783 -0.161693025575497 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O16 mock treatment 501930.0 -40500.0 -0.34 544480.0 2790.0 0.02 -0.8359 -0.799 333470.0 -81988.505434783 -0.49859776957679 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O17 mock treatment 496520.0 -45900.0 -0.39 497840.0 -43800.0 -0.37 -0.5055 -0.6244 327840.0 -87618.505434783 -0.532835562153094 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O18 mock treatment 479730.0 -62700.0 -0.53 496560.0 -45100.0 -0.38 -0.941 -0.9776 316230.0 -99228.505434783 -0.603439606879719 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O19 mock treatment 467420.0 -75000.0 -0.64 503710.0 -38000.0 -0.32 -0.8172 -0.9458 349440.0 -66018.505434783 -0.401479199871002 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O20 mock treatment 489150.0 -53300.0 -0.45 497370.0 -44300.0 -0.38 -1.1231 -0.9432 329060.0 -86398.505434783 -0.525416360209384 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O21 mock treatment 442650.0 -99800.0 -0.85 494560.0 -47100.0 -0.4 -0.7493 -0.7513 361350.0 -54108.505434783 -0.329050761223793 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O22 mock treatment 473550.0 -68900.0 -0.59 492090.0 -49600.0 -0.42 -1.1252 -0.9886 317920.0 -97538.505434783 -0.593162187793759 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O23 mock treatment 421280.0 -121000.0 -1.03 496740.0 -44900.0 -0.38 -1.6773 -0.9535 256960.0 -158498.505434783 -0.963879032456553 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base O24 mock treatment 448970.0 -93500.0 -0.8 429280.0 -112000.0 -0.95 -1.0332 -0.8039 417830.0 2371.494565217 0.0144218008916045 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P01 mock treatment 305940.0 -236000.0 -2.01 310490.0 -231000.0 -1.96 -2.3229 -0.8105 324640.0 -90818.505434783 -0.552295763972664 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P02 mock treatment 398400.0 -144000.0 -1.23 392900.0 -149000.0 -1.26 -2.1784 -0.9895 269860.0 -145598.505434783 -0.885430093871415 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P03 mock treatment 274080.0 -268000.0 -2.28 380590.0 -161000.0 -1.37 -2.5361 -0.8909 285480.0 -129978.505434783 -0.790439983739642 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P04 mock treatment 369390.0 -173000.0 -1.47 362360.0 -179000.0 -1.52 -2.033 -0.9003 303200.0 -112258.505434783 -0.682679116163778 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P05 mock treatment 384900.0 -158000.0 -1.34 265920.0 -276000.0 -2.34 -2.5454 -0.8848 311770.0 -103688.505434783 -0.630562263165744 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P06 mock treatment 372540.0 -170000.0 -1.45 352800.0 -189000.0 -1.6 -2.1589 -0.9222 295720.0 -119738.505434783 -0.728167337917021 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P07 mock treatment 351850.0 -191000.0 -1.62 321440.0 -220000.0 -1.87 -2.8667 -0.9526 155710.0 -259748.505434783 -1.57961198065386 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P08 mock treatment 390520.0 -152000.0 -1.29 399740.0 -142000.0 -1.2 -1.9361 -0.9417 255700.0 -159758.505434783 -0.971541486923009 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P09 mock treatment 339110.0 -203000.0 -1.73 322890.0 -219000.0 -1.86 -2.7632 -0.9518 217510.0 -197948.505434783 -1.20378683301343 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P10 mock treatment 373800.0 -169000.0 -1.43 284880.0 -257000.0 -2.18 -2.3489 -0.8581 289090.0 -126368.505434783 -0.768486443561941 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P11 mock treatment 291380.0 -251000.0 -2.14 342820.0 -199000.0 -1.69 -2.6807 -0.9053 239900.0 -175558.505434783 -1.06762623340713 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P12 mock treatment 362880.0 -180000.0 -1.53 383920.0 -158000.0 -1.34 -2.4892 -0.9874 242240.0 -173218.505434783 -1.05339596082657 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P13 mock treatment 299240.0 -243000.0 -2.07 421880.0 -120000.0 -1.02 -2.47 -0.9314 261960.0 -153498.505434783 -0.933472467113476 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P14 mock treatment 275440.0 -267000.0 -2.27 369460.0 -172000.0 -1.46 -2.4762 -0.8724 299320.0 -116138.505434783 -0.706274610870005 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P15 mock treatment 382180.0 -160000.0 -1.36 271630.0 -270000.0 -2.29 -2.906 -0.9247 160760.0 -254698.505434783 -1.54890134965735 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P16 mock treatment 238400.0 -304000.0 -2.59 391380.0 -150000.0 -1.28 -3.1332 -0.9358 212010.0 -203448.505434783 -1.23723405489081 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P17 mock treatment 248700.0 -294000.0 -2.5 323940.0 -218000.0 -1.85 -2.893 -0.8844 287230.0 -128228.505434783 -0.779797685869565 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P18 mock treatment 394960.0 -147000.0 -1.25 207200.0 -334000.0 -2.84 -3.014 -0.8747 185200.0 -230258.505434783 -1.40027405826039 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P19 mock treatment 362560.0 -180000.0 -1.53 348390.0 -193000.0 -1.64 -2.714 -0.9722 176080.0 -239378.505434783 -1.45573563344617 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P20 mock treatment 328010.0 -214000.0 -1.82 285870.0 -256000.0 -2.17 -3.1719 -0.9625 193160.0 -222298.505434783 -1.35186680623422 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P21 mock treatment 308230.0 -234000.0 -1.99 280750.0 -261000.0 -2.21 -2.9528 -0.916 243300.0 -172158.505434783 -1.04694976897384 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P22 mock treatment 238480.0 -304000.0 -2.59 146050.0 -396000.0 -3.36 -3.9771 -0.8874 210920.0 -204538.505434783 -1.24386268613561 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P23 mock treatment 314940.0 -227000.0 -1.94 207250.0 -334000.0 -2.84 -3.2399 -0.89 278840.0 -136618.505434783 -0.830819902515248 1001.0079 CellTiterGlo(1001.0079) MODYPatientCellProfiling 1001.0079.Base P24 mock treatment 255600.0 -287000.0 -2.44 193600.0 -348000.0 -2.95 -3.8219 -0.9178 187580.0 -227878.505434783 -1.38580053315709